Understanding and Treating Schizophrenia: Contemporary Research, Theory, and Practice

* Preface * Section I: The development, Evolution, Epidemiology, and Subsyndromes of Schizophrenia * Chapter 1. History of the Concept of Schizophrenia * The Premodern Period * The Nineteenth Century * Origins of the Concept of Schizophrenia * Emil Kraepelin * Adolph Meyer * Eugen Bleuler * Summary * Chapter 2. Evolving Diagnostic Criteria * Diagnosing Schizophrenia * DSM-I * DSM-II * Problems with Diagnostic Reliability * European Diagnostic Efforts * Research Definitions * DSM-III * DSM-IV * Reliability and Validity * Summary * Chapter 3. Epidemiology, Course, and Outcome * Prevalence and Incidence * Phases of Schizophrenia * Long-Term Outcome * Positive and Negative Symptoms * Symptom and Premorbid Predictors of Outcome * Schizophrenia and Comorbid Substance Use * The Role of Culture in Outcome: The WHO International Pilot Study of Schizophrenia (IPSS) * Summary * Chapter 4. Language, Thought, and Syndromes of Schizophrenia * Delusions? * Categories of Symptoms * Summary * Section II. Integrative Models and Level of Analysis * Chapter 5. Vulnerability-Stress Models * A "Two-Hit" Biological Model of Diathesis-Stress * Vulnerability * Stress * Summary * Chapter 6. Epistemology, General Systems Theory, and Schizophrenia * General Systems Theory * Summary * Section III. Biological Perspectives * Chapter 7. Genetics and Schizophrenia * Genetic Models * The Nature of Genetic Influence * Concordance Research * Basic Genetic Research * Summary * Chapter 8. Neurobiological Models and Research * Studies of Specific Brain Abnormalities * Neurobiological Modular Systems and Clusters of Schizophrenia Symptoms * Cognitive Dysmetria * Modular Disjunction * Dysfunctions in Interrelated Systems and Symptom Clusters * Summary * Chapter 9. Antipsychotic Medications and Neurochemical Theories * Efficacy of Typical Antipsychotics * The Dopamine Hypothesis * Atypical Antipsychotics * The Hyperdopaminergic Hypothesis and Glutamate * Schizophrenia: A Neurotransmitter Imbalance Syndrome? * Summary * Section IV. Cognitive-Behavioral, Neurocognitive, and Neurodevelopmental Research * Chapter 10. Neurocognitive and Neurodevelopmental Research * Neurocognitive Indicators of Vulnerability * Neurodevelopmental Precursors to Clinical Symptoms * Therapies for Neurocognitive Deficits * Summary * Chapter 11. Cognitive-Behavioral Approaches and Therapies * Applied Behavioral Analysis * The Cognitive-Behavioral Approach * Broad-Spectrum Cognitive Therapy * Symptom-Focused Cognitive Interventions * Social Cognition and Schizophrenia * Cognitive-Behavioral Intervention Programs Tailored to Symptom Phase * Personal Therapy (PT): A Disorder-Relevant Therapy * Summary * Section V. Psychodynamic, Phenomenological, and Family-Based Theories * Chapter 12. Psychodynamic Theories: The Role of Early Experience * Background * Sullivan's Interpersonal Theory * The Kleinian School * Margaret Mahler * Object Relations and Delusions * Robbins Hierarchical Systems/Psychoanalytical Model * Contemporary Psychodynamic Therapies * Summary * Chapter 13. Phenomenology and Schizophrenia * Delusions and the Relationship to the Outer World * The Process of Delusion Formation * Schizophrenic and Nonschizophrenic Delusions * Daseinanalysis * Summary * Chapter 14. Schizophrenia and the Family * Murray Bowen and the Washington Group * Theodore Lidz and the Yale Group * Y.O. Alanen and Finnish Family Research * The Palo Alto Group--Jackson, Bateson, Haley, Weakland, Satir, and Watzlawick * Experimental Family Studies--Mishler and Waxler * The Rochester Research Group--Wynne and Singer * Summary * Section VI. Psychodynamic, Phenomenological,