Essentials of Pathophysiology for Pharmacy

CELLULAR INJURY Cellular adaptation Mechanism of cellular injury Classification of cellular injury Manifestations of cellular injury Cell death Types of cellular necrosis Tissue repair mechanisms Steps in wound healing Factors that impair wound healing CANCER Estimated number of new cancer cases Cancer terminology Characteristics of neoplasia Theories of oncogenesis Cancer causing agents Manifestations of cancer Tumor staging Cancer detection Tumor markers Treatment of cancer DISORDERS OF HEMOSTASIS AND COAGULATION Steps in hemostasis Coagulation pathways Conditions leading to decreased coagulation Anticoagulant drugs Conditions leading to increased coagulation ALTERATIONS IN HEMATOLOGIC FUNCTION AND OXYGEN TRANSPORT Hematopoiesis Analysis of blood cells Anemia Sickle cell disease Thalassemia Polycythemia IMMUNE RESPONSE AND INFLAMMATION Components of the immune system Immune cell function Antibody structure and function Cytokine actions The inflammatory reaction Hypersensitivity reactions Anaphylaxis ACQUIRED IMMUNE DEFICIENCY SYNDROME HIV structure Stages of HIV infection Opportunistic infections in AIDS Epidemiology of HIV infection Laboratory diagnosis of HIV HIV treatment and prevention HIV drug resistance DISEASES OF VASCULAR SYSTEM Arterial diseases Atherosclerosis, lipoproteins Genetic disorders of lipid metabolism Aneurysm Vasospastic conditions Arterial inflammation Diseases of the veins Varicose veins Chronic venous insufficiency Venous thrombus Embolism Anticoagulant and Thrombolytic drug therapy ALTERATIONS IN BLOOD PRESSURE Primary or essential hypertension Blood pressure measures Risk factors for hypertension Manifestations of essential hypertension Treatment of hypertension Secondary hypertension Malignant hypertension Hypotension Causes of orthostatic hypotension DISEASES OF THE HEART Diseases of the pericardium Diseases of the myocardium Diseases of the endocardium and heart valves Congenital heart defects MYOCARDIAL ISCHEMIA Myocardial oxygen balance Manifestations of myocardial ischemia, types of angina pectoris Diagnosis of myocardial ischemia Treatment of myocardial ischemia MYOCARDIAL INFARCTION Coronary blood flow and myocardial infarction Manifestations of myocardial infarction Complications of myocardial infarction Compensatory mechanisms of myocardial infarction Treatment of myocardial infarction HEART FAILURE AND SHOCK Left heart failure Right heart failure Physiologic compensation for heart failure Diagnosis of congestive heart failure Treatment of congestive heart failure Circulatory shock, types. Stages of shock Complications of shock Treatment of shock ABNORMALITIES OF CARDIAC CONDUCTION Cardiac conduction system Cardiac action potential Electrocardiography Factors contributing to the development of a cardiac arrhythmia Mechanisms of cardiac arrhythmia Types of cardiac arrhythmia Heart Block Diagnosis of cardiac arrhythmia Treatment of cardiac arrhythmia DISORDERS OF THE RESPIRATORY SYSTEM Respiratory infections Obstructive pulmonary disorders Restrictive pulmonary disorders Respiratory failure ABNORMALITIES OF THE KIDNEY AND URINARY TRACT Functions of the kidney Renal regulation of blood flow Evaluation of renal function Diseases of the kidney Renal failure Renal dialysis Disorders of the bladder and urethra GASTROINTESTINAL DISORDERS Symptoms of gastrointestinal disease Abnormalities of the esophagus Disorders of the stomach Disorders of the intestines Disorders of the gall bladder Diverticular disease Colorectal cancer DISEASE OF THE LIVER AND EXOCRINE PANCREAS Viral hepatitis Jaundice Cirrhosis Alcoholic Liver Disease Liver cancer Disorders of the exocrine pancreas ENDOCRINE DISORDERS Hypersecretion of hormones Hyposecretion of hormones Altered responsiveness to hormones Hormones of the hypothalamus Hormones of the pituitary gland Disorders of the hypothalamus/anterior pituitary gland Disorders of the posterior pituitary gland Alterations in thyroid function Disorders of the adrenal cortex Disorders of the adrenal medulla DIABETES MELLITUS Hormones of the endocrine pancreas Type I diabetes mellitus Type II diabetes mellitus Treatment of diabetes mellitus Long term complications of diabetes mellitus Gestational diabetes REFERENCES