cssi/SciSciGPT-SciSciNet huggingface dataset:
Paulus im ‘Zwischenzustand’: Phil 1.23 und die Ambivalenz des Sterbens als Provokation

Das von Paulus in Phil 1.23 angesprochene ‘mit Christus Sein’ beschreibt eine unmittelbar postmortale, jenseitige Christusgemeinschaft, die im Vergleich mit sonstigen Aussagen des Paulus zur Totenerweckung erst bei der endzeitlichen Parusie Christi auffallig wird. Daraus ergibt sich die Frage, auf welchem religionsgeschichtlichen Hintergrund Paulus bzw. seine Leserinnen und Leser diese Vorstellung erfassen konnten. Die hellenistische Literatur bietet dabei lediglich Sprachparallelen (abwagender Vergleich von Leben und Tod) sowie gewisse formale (Synkrisis) und inhaltliche (Suizid-Diskussion der Antike) Analogien; es bleiben weite Differenzen bestehen. Ertragreicher erweist sich die Suche in Texten des Fruhjudentums, deren Aussagen sich in drei Theorien bundeln lassen: Das Vorbild der Martyrer bzw. der ‘Gerechten’ als sogleich mit dem Tod zu Gott erhobenen Gruppen wird verschiedentlich in der Forschung vertreten, eine Orientierung an den Vatern Israels wird als Alternative dazu im vorliegenden Aufsatz neu entwickelt, so dass die Denkmoglichkeit der paulinischen Aussage plausibel gemacht werden kann. Dies mundet in eine pragmatische Analyse der spezifischen Aussagegestalt von Phil 1.18b–26, die den Text hinsichtlich einer potentiellen und intendierten Wirkung auf die Adressatinnen und Adressaten deutet.
Popplet for Higher Education: Supporting Organization and Collaboration

This article shares an innovative, technology-based approach to teaching using an old tool, the graphic organizer, in a web-based platform. Popplet is a Web 2.0 tool that allows users to quickly and simply create visually appealing graphic organizers that integrate text, image, video, and Internet resources to organize and present information. Popplet also supports collaboration as multiple users may develop a graphic organizer together and comment on each other’s work. Strategies for using Popplet in higher education as a means of supporting Universal Design for Learning principles are provided.
Successfully applying software metrics

The word success is very powerful. It creates strong, but widely varied, images that may range from the final seconds of an athletic contest to a graduation ceremony to the loss of 10 pounds. Success makes us feel good; it's cause for celebration. All these examples of success are marked by a measurable end point, whether externally or self-created. Most of us who create software approach projects with some similar idea of success. Our feelings from project start to end are often strongly influenced by whether we spent any early time describing this success and how we might measure progress. Software metrics measure specific attributes of a software product or a software development process. In other words, they are measures of success. It's convenient to group the ways that we apply metrics to measure success into four areas. What do you need to measure and analyze to make your project a success? We show examples from many projects and Hewlett Packard divisions which may help you chart your course. >
Who was Elizabeth Dodderidge Thorp Powell and Why is the Fact She Took Her Former Father-in-Law to Court in 1693 Important?

This article began with a retirement gift from Lurie's department in 2010. Knowing of her special interest in New Jerseycolonial history, the department gave her a 1693 court writ from theEast Jersey colony. Lurie found this an intriguing but challengingdocument. Who were the people involved in this suit? Why wasa woman suing a man over a property dispute? The article revealsmuch about equity and fairness in the colonial courts and socialmatters of inheritance and property during colonial times. Lurietakes us along on a historical journey that shows us how initialquestions lead to dead-ends because of lack of documentationand how new lines of research developed as she uncovered ne
Canstatin, a novel matrix-derived inhibitor of angiogenesis and tumor growth

We isolated and identified an endogenous 24-kDa human basement membrane-derived inhibitor of angiogenesis and tumor growth, termed canstatin. Canstatin, a fragment of the alpha2 chain of type IV collagen, was produced as a recombinant molecule in Escherichia coli and 293 embryonic kidneys cells. Canstatin significantly inhibited human endothelial cell migration and murine endothelial cell tube formation. Additionally, canstatin potently inhibited 10% fetal bovine serum-stimulated endothelial cell proliferation and induced apoptosis, with no inhibition of proliferation or apoptosis observed on non-endothelial cells. Inhibition of endothelial proliferation was not concomitant with a change in extracellular signal-regulated kinase activation. We demonstrate that apoptosis induced by canstatin was associated with a down-regulation of the anti-apoptotic protein, FLIP. Canstatin also suppressed in vivo growth of large and small size tumors in two human xenograft mouse models with histology revealing decreased CD31-positive vasculature. Collectively, these results suggest that canstatin is a powerful therapeutic molecule for suppressing angiogenesis.
Commentary on an article by Dino Samartzis, DSc, et al.: "A population-based study of juvenile disc degeneration and its association with overweight and obesity, low back pain, and diminished functional status".

Samartzis and his colleagues report on a cross-sectional study of Chinese youth, aged thirteen to twenty years. Out of a larger cohort of 1989 Southern Chinese volunteers, they identified eighty-three individuals in this particular age group who did not have spinal deformity. Fifty-four of them, twenty-two males and thirty-two females, had no evidence of disc degeneration on a T2-weighted sagittal magnetic resonance imaging (MRI) of the lumbar spine. Twenty-nine, sixteen males and thirteen females, did exhibit MRI evidence of juvenile disc degeneration. Statistical analysis showed no significant difference in age or sex between the two groups. However, weight, height, and body-mass index (BMI) were all significantly higher in the group with juvenile disc degeneration. The odds ratio for having disc degeneration was 14.19 (95% confidence interval [CI], 1.44 to 140.40) if an individual was overweight or obese compared with underweight. Interestingly, it was a remarkable 11.70 (95% CI, 1.34 to 102.37) even if the BMI was normal; again, note that the risk was relative to being underweight. The broad confidence intervals are also important to note. The odds ratio for having juvenile disc degeneration was 6.57 (95% CI, 1.96 to 22.02) …
Modulated-Beam Cathode-Ray Phase Meter

This paper describes a phase meter developed to measure the phase-shift characteristics of amplifiers used in vibration-measurement work. It employs a cathode-ray tube, in conjunction with a circuit establishing a circular time base on the screen of the tube, and a "clipper" circuit fed in turn by the two voltages, the phase difference of which it is desired to measure. The change in angular position of the semicircle obtained on the screen is the phase difference in the voltages. The method possesses several distinct advantages, including indication of the sense of the phase difference and accurate operation at subaudible frequencies.
Photoexcited structural dynamics of an azobenzene analog 4-nitro-4′-dimethylamino-azobenzene from femtosecond stimulated Raman

Azobenzenes are used in many applications because of their robust and reversible light induced trans cis isomerization about the NN bond, but the mechanism of this ultrafast reaction has not been conclusively defined. Addressing this problem we have used Femtosecond Stimulated Raman Spectroscopy (FSRS) to determine the structural transients in the trans → cis photoisomerization of the azobenzene derivative, 4-nitro-4′-dimethylamino-azobenzene (NDAB). Key marker modes, such as the 1570/1590 cm−1 NO2 stretch and the 1630 cm−1 C–N(Me)2 stretch, enable the separation and analysis of distinct trans and cis photoproduct dynamics revealing the 400 fs Frank-Condon relaxation, the 800 fs timescale of the cis product formation and the 2 ps emergence and 8 ps relaxation of the unsuccessful ground state trans species. Based on these observations, we propose a reaction mechanism, including initial dilation of the CNN bend later joined by quick movement along the CCNN, CNNC and NNCC torsional coordinates that constitutes a mixed inversion-rotation mechanism.
ADMA and hyperhomocysteinemia

Hyperhomocysteinemia is a risk factor for cardiovascular disease and stroke. Like many other cardiovascular risk factors, hyperhomocysteinemia produces endothelial dysfunction due to impaired bioavailability of endothelium-derived nitric oxide (NO). The molecular mechanisms responsible for decreased NO bioavailability in hyperhomocysteinemia are incompletely understood, but emerging evidence suggests that asymmetric dimethylarginine (ADMA), an endogenous inhibitor of NO synthase, may be a key mediator. Homocysteine is produced during the synthesis of ADMA and can alter ADMA metabolism by inhibiting dimethylarginine dimethylaminohydrolase (DDAH). Several animal and clinical studies have demonstrated a strong association between plasma total homocysteine, plasma ADMA, and endothelial dysfunction. These observations suggest a model in which elevation of ADMA may be a unifying mechanism for endothelial dysfunction during hyperhomocysteinemia. The recent development of transgenic mice with altered ADMA metabolism should provide further mechanistic insights into the role of ADMA in hyperhomocysteinemia.
DISTRIBUTED PARALLEL PROCESSING TECHNIQUES FOR ADAPTIVE SONAR BEAMFORMING

Quiet submarine threats and high clutter in the littoral environment increase computation and communication demands on beamforming arrays, particularly for applications that require in-array autonomous operation. By coupling each transducer node in a distributed array with a microprocessor, and networking them together, embedded parallel processing for adaptive beamformers can glean advantages in execution speed, fault tolerance, scalability, power, and cost. In this paper, a novel set of techniques for the parallelization of adaptive beamforming algorithms is introduced for in-array sonar signal processing. A narrowband, unconstrained, Minimum Variance Distortionless Response (MVDR) beamformer is used as a baseline to investigate the efficiency and effectiveness of this method in an experimental fashion. Performance results are also included, among them execution times, parallel efficiencies, and memory requirements, using a distributed system testbed comprised of a cluster of workstations connected by a conventional network.
A viral epitope that mimics a self antigen can accelerate but not initiate autoimmune diabetes

We document here that infection of prediabetic mice with a virus expressing an H-2Kb-restricted mimic ligand to a self epitope present on beta cells accelerates the development of autoimmune diabetes. Immunization with the mimic ligand expanded autoreactive T cell populations, which was followed by their trafficking to the islets, as visualized in situ by tetramer staining. In contrast, the mimic ligand did not generate sufficient autoreactive T cells in naive mice to initiate disease. Diabetes acceleration did not occur in H-2Kb-deficient mice or in mice tolerized to the mimic ligand. Thus, arenavirus-expressed mimics of self antigens accelerate a previously established autoimmune process. Sequential heterologous viral infections might therefore act in concert to precipitate clinical autoimmune disease, even if single exposure to a viral mimic does not always cause sufficient tissue destruction.
Cafecitos y Nostalgia: Building Transnational Landscapes in the Cuban Diaspora

: [in focus, place, transnational landscape, cuba, Miami Cuban, Cuban American, diaspora]
Role of toll-like receptor signalling in Aβ uptake and clearance

Deposits of amyloid beta-protein (Abeta) in neuritic plaques and cerebral vessels are a pathological hallmark of Alzheimer's disease. Fibrillar Abeta deposits are closely associated with inflammatory responses such as activated microglia in brain with this disease. Increasing lines of evidence support the hypothesis that activated microglia, innate immune cells in the CNS, play a pivotal role in the progression of the disease: either clearing Abeta deposits by phagocytic activity or releasing cytotoxic substances and pro-inflammatory cytokines. Toll-like receptors (TLRs) are a family of pattern-recognition receptors in the innate immune system. Exogenous and endogenous TLR ligands activate microglia. To investigate the role of TLR4 in the amyloidogenesis in vivo, we determined the amounts of cerebral Abeta in Alzheimer's disease mouse models with different genotypes of TLR4 using three distinct methods. We show that mouse models (Mo/Hu APPswe PS1dE9 mice) homozygous for a destructive mutation of TLR4 (Tlr(Lps-d)/Tlr(Lps-d)) had increases in diffuse and fibrillar Abeta deposits by immunocytochemistry, fibrillar Abeta deposits by thioflavine-S staining and buffer-soluble and insoluble Abeta by ELISA in the cerebrum, as compared with TLR4 wild-type mouse models. Although the differences in these parameters were less significant, mouse models heterozygous for the mutation (Tlr(Lps-d)/) showed co-dominant phenotypes. Consistent with these observations in vivo, cultured microglia derived from Tlr(Lps-d)/Tlr(Lps-d) mice failed to show an increase in Abeta uptake after stimulation with a TLR4 ligand but not with a TLR9 ligand in vitro. Furthermore, activation of microglia (BV-2 cell) with a TLR2, TLR4 or TLR9 ligand, markedly boosted ingestion of Abeta in vitro. These results suggest that TLR signalling pathway(s) may be involved in clearance of Abeta-deposits in the brain and that TLRs can be a therapeutic target for Alzheimer's disease.
Use of Pricing Schemes for Differentiating Information Goods

Information goods vendors offer different pricing schemes such as per user pricing and site licensing. Why do competing sellers adopt different pricing schemes for the same information good? Pricing schemes affect buyers' usage levels and thus the revenue generated from different segments of buyers. This can allow competing firms in a duopoly to differentiate themselves by offering different pricing schemes. Such strategic use of pricing schemes can allow undifferentiated sellers to earn substantial profits in a friction-free market for a commoditized information good. These conditions would otherwise lead to the Bertrand equilibrium and zero profits. We show that adopting asymmetric pricing schemes can be a Nash equilibrium for information goods with negligible marginal cost of production. We extend our model to the case of information goods that are horizontally differentiated and show that sellers will offer a single-pricing scheme that is different from competitors when the sellers are weakly differentiated. When the sellers are strongly differentiated, each seller will offer multiple pricing schemes. We show that it can be optimal for a seller to offer multiple pricing schemes---metered and flat fee pricing schemes, even in the absence of transactions costs.
Effect of DMT1 knockdown on iron, cadmium, and lead uptake in Caco-2 cells.

DMT1 (divalent metal transporter 1) is a hydrogen-coupled divalent metal transporter with a substrate preference for iron, although the protein when expressed in frog oocytes transports a broad ran...
Cinacalcet: An oral calcimimetic agent for the management of hyperparathyroidism.

Abstract Background: Uncontrolled hyperparathyroidism (HPT), particularly HPT resulting from chronic kidney disease (CKD), is associated with significant morbidity and cardiovascular mortality. Traditional medical therapy (eg, vitamin D sterols, calcium, phosphate binders) has been inadequate for the management of HPT and its vascular and skeletal complications. Objective: The goal of this article was to reviewthe efficacy and safety profile of cinacalcet, a second-generation calcimimetic, in the management of HPT secondary to CKD, primary HPT, and parathyroid carcinoma. Methods: MEDLINE, Web of Science, and InternationalPharmaceutical Abstracts were searched from 1995 to July 2005 using the terms cinacalcet, AMG 073, KRN 1493, calcimimetics, bypercalcemia , and byperparatbyroidism . Results: Compared with placebo, cinacalcet significantly reduced parathyroid hormone levels within 2 to 4 hours after administration ( P P Conclusions: Based on the available evidence,cinacalcet is effective and well tolerated in the treatment of secondary HPT and refractory parathyroid carcinoma. Its use in primary HPT appears promising. Further investigations are needed to determine if cinacalcet can prevent the long-term complications of HPT and reduce mortality.
Neuropathology of Schizophrenia: Cortex, Thalamus, Basal Ganglia, and Neurotransmitter-specific Projection Systems

This article reviews neuropathological studies in the search for an anatomical correlate of schizophrenia. Replication of many results has proven to be difficult. A consistent finding is the lack of significant gliosis in the neocortex. Intriguing findings that need further corroboration include decreased volume and cell number of the mediodorsal thalamic nucleus, cytoarchitectural alterations of the prefrontal cortex and upper layers of the anterior cingulate gyrus, and superior temporal gyrus abnormalities. Most neuropathological studies investigate regional brain volume and cell density. Highly variable shrinkage of brain tissue postmortem makes these estimates prone to bias and often not comparable across studies. So far, no strong clinicopathological correlations and no pathological criteria to diagnose schizophrenia have been established.
floating. No gears shifting.

It is impressive how, in Prasenjit Duara's essay, Asian regions are understood and presented—in the breadth of the world, not as objects with sharp edges, or compact entities of cultures, economies, and politics, not as blocks of which the present and the global so often are still thought to be made. Reading Duara's essay, I was made to think of the celebrated Japanese architect Fumihiko Maki's current grand plan for Singapore, the epitome of Asia today, a design conceived not as a space made of buildings, offices, and flats, not of blocks, but of flows—bridges and flyovers, “links,” as Maki calls them. These links are there as the most powerful part of the whole, making the city-state space by cutting through it, over the blocks, and along them. The links are empowered to make everything in the city-state to face the open, and to move into the open. A skeptic, of course, may ask, “into what open?” Indeed, the “links” of Singapore, at least those already in action, often lead from offices, flats, and blocks into one mega-supermarket and then into another.
Gait Evaluation of a Novel Hip Constraint Orthosis With Implication for Walking in Paraplegia

The aim of this study was to determine the effects of a newly developed reciprocal gait orthosis (RGO) with a variable constraint hip mechanism (VCHM) on the kinematics and kinetics of normal gait. The VCHM was compared with the isocentric reciprocating gait orthosis (IRGO) for walking after paraplegia. Both the VCHM and the IRGO were evaluated with able-bodied volunteers with the hip reciprocating mechanisms coupled and uncoupled. The VCHM was further evaluated with context-dependent coupling based on a finite-state control algorithm utilizing information from brace-mounted sensors. Walking performance for each brace condition was also compared to normal walking without an orthosis. Without the hip controller, the VCHM affected the kinematics of the hip joint in a similar manner as the IRGO, regardless of whether the hip reciprocator was coupled or uncoupled. With the controller active, hip kinematics with the VCHM were closer to normal gait than with the IRGO or any other condition tested (Intraclass correlation coefficient, ICC=0.96). The effects of the braces on the knee and ankle angles were not as prominent as their effects on the hip angles. In terms of kinetics, the VCHM with controller active allowed the generation of joint moments that were closer to normal (ICC=0.80) than the IRGO with hips coupled (ICC= 0.68). There was no statistically significant difference between the various conditions tested in terms of step-length ( p <; 0.01) and no statistically significant difference in the preferred walking speed between the IRGO and normal walking, whether or not the hips were coupled. However, there was a 25% reduction in walking speed with the VCHM when compared to normal, and the relative magnitudes of the EMG activity of three muscles (tibialis anterior, quadriceps, and hamstrings) were also higher with the VCHM than with either the IRGO or normal gait, likely due to the additional weight of the mechanism. Overall, the VCHM with controller active provided smooth control of the hip joints via context-dependent coupling and allowed for increased hip flexion relative to the IRGO. The results suggest that the VCHM with controlled joint coupling may eventually be a valuable component of a hybrid system combining functional electrical stimulation (FES) with orthotics.
Comparison of a recurrent neural network PV system model with a traditional component-based PV system model

Photovoltaic (PV) system modeling is used throughout the photovoltaic industry for the prediction of PV system output under a given set of weather conditions. PV system modeling has a wide range of uses including: pre-purchase comparisons of PV system components, system health monitoring, and estimation of payback (return on investment) times. In order to adequately model a PV system, the system must be characterized to establish the relationship between given weather inputs (e.g., irradiance, spectrum, temperature) and desired system outputs (e.g., AC power, module temperature). Traditional approaches to system characterization involve characterizing and modeling each component in a PV system and forming a system model by successively using component models. This paper compares a traditional modeling approach using the Sandia Photovoltaic Array Performance Model [1] to a new method of characterization using a recurrent neural network (RNN). The Sandia model predicts system performance from given weather data and individual component characterizations using a defined set of equations, while the RNN “learns” the input/output relationships by training on concurrent weather and performance data. The comparison of a traditional modeling technique and the new RNN method serves to validate the accuracy of the new method in comparison to a widely accepted modeling technique. Modeling using an RNN may be advantageous when component models are not available for the components in a PV system, when the components of a PV system are unknown to the modeler, or when system components are installed or altered in such a fashion that their model parameters are no longer applicable.
Further Studies on Hormone Excretion During the Menstrual Cycle

Summary Day-by-day assays, for both estrin and gonadotropin, during a total of 29 cycles, of 5 subjects, have been made. The results were as follows: 1. As regards time of ovulation: Of the 29 eyeles, 25 gave evidence of ovulation occurring between the twelfth and sixteenth days preceding the onset of the next menstruation; the other 4 were considered anovulatory. 2. As regards hormone excretion levels: The amount of gonadotropin produced during peaks of activity was equivalent to from 4 to 16 I. U. Some evidence was obtained supporting the view of hypophyseal activity at other times than the mid-interval. The excretion of estrin took place in two waves, the daily output at the peak being approximately 800 1. 1:". Some degree of estrin excretion may take place at other times during tfiv cycle except during the first week. 3. As regards time relationship of hormone excretion: Invariably the ovarian activity, as indicated by increasing estrin excretion, precedes hypophyseal activity, as indicated by the gonadotropin peak. On the basis of this finding a theory of the mechanism controlling ovulation is tentatively suggested.
Comparison of the wear rates of twenty-eight and thirty-two-millimeter femoral heads on cross-linked polyethylene acetabular cups in a wear simulator.

Background: The use of larger femoral head sizes in total hip arthroplasty has been shown to reduce the rate of dislocation and to increase the range of motion; however, such components have been associated with unacceptably high polyethylene wear rates. Studies have shown dramatic differences in wear rates between nominally cross-linked polyethylene (i.e., polyethylene that is cross-linked during radiation sterilization) and elevated cross-linked polyethylene (i.e., polyethylene that is cross-linked to a higher degree than that obtained by radiation sterilization alone). The aim of this study was to test the effect of increased cross-linking and of increased head size on polyethylene wear rates. Methods: Four groups of acetabular liners obtained from a single manufacturer, including 28-mm-diameter nominally cross-linked, 32-mm-diameter nominally cross-linked, 28-mm-diameter elevated cross-linked, and 32-mm-diameter elevated cross-linked polyethylene liners, were tested. Three implants from each group were tested in a twelve-station hip wear simulator with use of 90% bovine serum as a lubricant. The liners were articulated with the appropriately sized cobalt-chromium femoral head. Additional liners from each design were subjected only to the same load without motion to serve as load-soak controls to account for any weight gain due to fluid absorption. Gravimetric analysis was performed every 500,000 cycles for a total of five million cycles. Results: Nominally cross-linked liners demonstrated mean wear rates of 14.97 and 16.92 mg per million cycles for the 28-mm and 32-mm head sizes, respectively. Both of the elevated cross-linked liners had significantly lower wear rates than the nominally cross-linked liners, with a mean of 1.51 and 2.57 mg per million cycles for the 28-mm and 32-mm head sizes, respectively (p < 0.001). Conclusion and Clinical Relevance: The dramatic reduction in wear rates with polyethylene cross-linking, even with the larger head size, may increase the potential for use of 32-mm head components in total hip arthroplasty.
Interactive Visualization of Netflow Traffic

We introduce a novel tool for visualizing netflow traffic on enterprise networks called 3D Parallel Coordinate Planes (3DPCP). This tool provides operators with the ability to manipulate the visual flow of network traffic information by arranging two-dimensional planes along a vertical time axis in 3D space.
Competition Law in the United States

In one sense, U.S. competition law is very easy. U.S. antitrust lawyers usually worry about only three statutory provisions: Sherman Act Section 1, Sherman Act Section 2, and Clayton Act Section 7. The first prohibits agreements in restraint of trade, the second monopolization and attempts and conspiracies to monopolize, and the last mergers and acquisitions that may substantially lessen competition. With a few exceptions, that is all the statutory law one needs to know. In another sense, U.S. competition law is very hard. Those few important statutory provisions answer few questions. The courts treat competition law as a kind of common law, freely changing legal standards from time to time without Congressional guidance. Legal standards are informed by economics, moreover, so as economics evolves the law may evolve with it. Two federal enforcement agencies and numerous state attorneys general enforce the law and participate actively in trying to shape its evolution, while the strong majority of lawsuits are filed by private parties. This chapter reviews the history of US antitrust law and considers how it is enforced. It then sets out important highlights of much of substantive antitrust law. Any antitrust system - indeed, any legal system - is the product of interaction between substance and procedure. One of the glories of the U.S. system, while also one of its challenges, is the leading role played by private enforcement (especially treble damages enforcement). The legal rules that comprise American antitrust are clearer and more reliable because they have to be. This overview shows that U.S. competition law is the product of legal evolution, informed by changes in economic understanding. The antitrust agencies play critical roles not just by filing lawsuits but also by participating in the antitrust conversation by filing amicus briefs, issuing guidelines, giving speeches, doing studies, and conducting hearings and workshops. That evolution continues to this day; indeed, an Antitrust Modernization Commission has been charged formally with considering whether to propose changes.
High Thermoelectric Performance SnTe-In2Te3 Solid Solutions Enabled by Resonant Levels and Strong Vacancy Phonon Scattering

Herein, we report a significantly improved thermoelectric figure of merit ZT of ∼1.1 at ∼923 K in p-type SnTe through In2Te3 alloying and iodine doping. We propose that the introduction of indium at Sn sites in SnTe creates resonant levels inside the valence bands, thereby considerably increasing the Seebeck coefficients and power factors in the low-to-middle temperature range. Unlike SnTe–InTe, the SnTe–In2Te3 system displays much lower lattice thermal conductivity. Utilizing a model for point defect scattering, we analyze the origin of the low thermal conductivity in SnTe–In2Te3 and attribute it mainly to the strong vacancy originated phonon scattering between Sn atoms and the vacancies introduced by In2Te3 alloying and partly to the interfacial scattering by In-rich nanoprecipitates present in SnTe matrix. By alloying only In2Te3 with SnTe, a ZT value of ∼0.9 at 923 K was achieved. ZT can be further increased to ∼1.1 at 923 K through adjusting the charge carriers by iodine doping at Te sites.
Tuberculosis in free-ranging, semi free-ranging and captive cervids.

Summary: Cervids were one of the earliest sources of food for humans. Evidence exists of some degree of human management of cervids in Norway over 50,000 years ago. Cervids are popular wild animals for viewing in National Parks and Wildlife Reserves; they have also become popular as an alternative livestock species, and are being farmed and ranched commercially. Confinement of animals and the resultant increase in population density have increased the likelihood of infectious and parasitic diseases. Cervids are susceptible to tuberculosis caused by Mycobacterium spp. (M. bovis, M. tuberculosis, M. avium). Tuberculosis has affected the cervid industry, causing concern among wildlife managers and regulatory agencies in countries where attempts are being made to eradicate tuberculosis. The author discusses the epizootiology of tuberculosis in the various existing management situations. Husbandry practices which either favour or inhibit the potential occurrence of tuberculosis are described.
HEMAGGLUTINATION AND HEMAGGLUTINATION-INHIBITION WITH ADENOVIRUS TYPE 12.

SummaryHemagglutmation has been demonstrated with the prototype Huie strain and two nonprototype strains of adenovirus type 12. This viral type resembles those classified in Group 3 in that hemagglutination occurred with rat cells in the presence of hetero-typic immune serum. Hemagglutination was specifically inhibited by immune serum to adenovirus type 12, but not immune serum to other adenoviruses. The identity of the hemagglutinating virus as adenovirus type 12 was confirmed by both hemagglutination–inhibition and neutralization tests with reference immune sera prepared in other laboratories.
Complementary detection of prostate-specific antigen using In2O3 nanowires and carbon nanotubes.

We report complementary detection of prostate-specific antigen (PSA) using n-type In2O3 nanowires and p-type carbon nanotubes. Our innovation involves developing an approach to covalently attach antibodies to In2O3 NW surfaces via the onsite surface synthesis of phosphonic acid−succinylimide ester. Electronic measurements under dry conditions revealed complementary response for In2O3 NW and SWNT devices after the binding of PSA. Real-time detection in solution has also been demonstrated for PSA down to 5 ng/mL, a benchmark concentration significant for clinical diagnosis of prostate cancer, which is the most frequently diagnosed cancer.
Winking and Giggling at Creeping Death: Thanatophobia and the Rhetoric of Save the Ta-Tas

This article offers an examination of the rhetoric of Save the Ta-Tas, a breast cancer awareness and fund-raising organization whose breast cancer advocacy products are highly sexualized, flirtatious, cheeky, and irreverent, especially in contrast to traditional discourses about breast cancer that have tended to render the afflicted as brave warriors or infantile and docile. Reading the organization’s range of merchandise as a discourse, I argue for a post-Marxist perspective that understands these texts as part of an important moment where breast cancer advocacy is disarticulated from the specter of death in order to appeal to a thanatophobic public.
The germination ecology of Helonias bullata L. (swamp pink) with respect to dry, saturated, and flooded conditions

Abstract Poor sexual recruitment is a major conservation concern for the rare obligate wetland plant Helonias bullata L. (swamp pink). Helonias predominately occurs in forested wetlands amongst hummock-hollow topography where water levels fluctuate spatially and temporally, creating a wide variety of moisture microsite conditions for germination. To determine how moisture conditions affect the germination response of Helonias seeds, germination percentages and rates were compared after seeds were exposed to dry, saturated (stream margin), and flooded (floating and submerged) conditions in a growth chamber and field for 1–35 days. Helonias final germination percentages were greater than 50% after exposure of all conditions, except dry conditions in the growth chamber. Moisture availability at the time of seed arrival was the main factor that influenced the germination of Helonias. Helonias seeds exposed to saturated and flooded conditions germinated within a short time frame (10-30 days). Rapid germination may be important for Helonias plants in forested wetlands where variable moisture conditions can create a narrow window for regeneration. For both the growth chamber and field experiment, final germination percentages were significantly higher (p
The influence of early age mastectomy and unilateral ovariectomy on reproductive performance of the bovine.

The effects of mastectomy and unilateral ovariectomy and their interaction during the postpartum period were examined in 26 Angus heifers. At birth, the animals were assigned to a 2 x 2 factorial arrangement of treatments: mastectomy and unilateral ovariectomy, mastectomy, unilateral ovariectomy and unoperated suckled control. Surgeries were performed at approximately 2 months of age, and animals were observed through three consecutive postpartum intervals (PP1, PP2, and PP3). There were no significant influences of mastectomy or ovariectomy on age at puberty, age at first conception or services required for first conception. Mastectomy reduced the number of days from parturition to ovulation (PP1, 32.1 vs 52.5, P less than .01; PP2, 21.6 vs 59.9, P less than .01; PP3, 20.6 vs 46.7, P less than .01) The interval from parturition to first estrus was shorter for heifers in the mastectomized group (PP1, 45.3 vs 76.2, P less than .05; PP2, 28.7 vs 69.9, P less than .01; PP3, 32.4 vs 62.3, P less than .05) as was the interval from parturition to conception during PP2 (60.0 vs 104.9, P less than .05). The interval between calvings was shorter for heifers in the mastectomized group than for controls, but the difference was significant only between the second and third parturitions: 338.5 vs 399.2 (P less than .01). Mastectomy reduced the standard deviation for the interval between parturition 2 and parturition 3 (55.9 vs 15.9; P less than .01), the interval between parturition and return to estrus in PP2 (56.3 vs 11.4; P less than .01) and the interval from calving to conception PP1 (92.2 vs 31.4; P less than .01). Unilateral ovariectomy did not have a significant influence on any of the postpartum intervals, nor were there any significant interactions.
Developing children's cultural awareness and empathy through games and fairy tales

This article explores how computer games can be developed to engage young children in critical discussions of cultural awareness and empathy in or out of classrooms. In order to answer the question "How can we expose children to different cultures and help them develop cultural awareness and empathy?" we are building a computer game for young children (5 to 7 years old) based on a Russian traditional fairy tale "The Magic Swan Geese." As a framework for designing the game, we draw on research on computer game design, early childhood development, and fairy tales literature. Through creating a pilot game we will test the feasibility of translating the theory of the design framework for into practice. This paper presents the design framework, the design of the game, and data from this on-going research and development project.
Education and continuing training for art librarianship: A North American Perspective

There are 58 universities in the US and Canada which offer graduate degrees in library and information science. At 33 of these, students can take elective courses in subject areas such as art history, but only eight of them provide a special course focussing on art librarianship. There are, however, numerous courses and work study oportunities which allow a student to prepare for jobs in this field. An annual survey conducted by ARLIS/NA reveals some interesting facts regarding educational opportunities, and these facts illustrate a tendency towards intermixing generalist and specialist aspects of professional education. The College of Library and Information Services, University of Maryland, offers a course in ‘Literature and Research in the Arts’, enabling library science students to explore the ‘bibliography’ of art (including electronic sources) as one element in a broader program of study.
The multiple conformational charge states of zinc(II) coordination by 2His-2Cys oligopeptide investigated by ion mobility-mass spectrometry, density functional theory and theoretical collision cross sections.

Whether traveling wave ion mobility-mass spectrometry (IM-MS), B3LYP/LanL2DZ density functional theory, and ion size scaled Lennard-Jones (LJ) collision cross sections (CCS) from the B3LYP optimized structures could be used to determine the type of Zn(II) coordination by the oligopeptide acetyl-His1 -Cys2 -Gly3 -Pro4 -Tyr5 -His6 -Cys7 (amb5 ) was investigated. The IM-MS analyses of a pH titration of molar equivalents of Zn(II):amb5 showed that both negatively and positively charged complexes formed and coordination of Zn(II) increased as the His and Cys deprotonated near their pKa values. The B3LYP method was used to generate a series of alternative coordination structures to compare with the experimental results. The method predicted that the single negatively charged complex coordinated Zn(II) in a distorted tetrahedral geometry via the 2His-2Cys substituent groups, whereas, the double negatively charged and positively charged complexes coordinated Zn(II) via His, carbonyl oxygens and the C-terminus. The CCS of the B3LYP complexes were calculated using the LJ method and compared with those measured by IM-MS for the various charge state complexes. The LJ method provided CCS that agreed with five of the alternative distorted tetrahedral and trigonal bipyramidal coordinations for the doubly charged complexes, but provided CCS that were 15 to 31 A2 larger than those measured by IM-MS for the singly charged complexes. Collision-induced dissociation of the Zn(II) complexes and a further pH titration study of amb5B , which included amidation of the C-terminus, suggested that the 2His-2Cys coordination was more significant than coordinations that included the C-terminus. Copyright © 2016 John Wiley & Sons, Ltd.
Manufacturing challenges and method of fabrication of on-chip capacitive digital isolators

A robust and innovative method of fabrication of on-chip capacitive digital isolators integrated in a high precision analog CMOS process is presented in this paper. Several dielectric materials such as TEOS, HDP, silicon nitride, silicon oxynitride, with different film stresses were evaluated for this capacitor in order to achieve the high breakdown voltage (RMS and surge) requirements of the isolation capacitor while ensuring wafer manufacturability. Impact of various integration schemes and combinations of the dielectric layers on the capacitor breakdown voltage performance along with a package and wafer-level reliability assessment of these integration schemes is discussed.
Immunologic Responder Groups.

Abstract Abstract SCI-47 Transfusion medicine has long recognized that there is significant variation in the human immune response to red blood cell (RBC) transfusions.1 All allogeneic RBC transfusions expose the recipient to multiple foreign antigens, but very few RBC transfusions induce a detectable humoral immune response. Using statistical analyses of antibody responses among transfused patient populations, we found that the response closely approximates a geometric distribution that would be predicted by a random memory-less (stochastic) process. These statistical analyses demonstrate that most patients fail to mount immune responses to RBC transfusions but a distinct group of patients, termed potential responders, is capable of mounting an immune response to blood transfusions. Potential responders comprise approximately 13% of the transfused population and this proportion does not depend on pathologic diagnoses, age, gender or racial group. The only group that has a higher rate of potential responders are pregnant women, but those patients have a second route of antibody exposure. Although the ability to immunologically respond to blood transfusions appears to be limited to the relatively small population of potential responders, even potential responders do not mount an immune response to most RBC transfusions. Additionally, the specific antibodies that patients make are not completely independent of each other. Indeed, patients who have made some specific antibodies are more likely to subsequently make one set of anti-erythrocyte antibodies and less likely to make another set of anti-erythrocyte antibodies. This suggests that the potential immune repertoire differs between patients and the difference in potential repertoire is not solely explained by the antigens expressed on the patients' erythrocytes. Moreover, the potential repertoire is influenced by the age of the patient. Younger patients have a more diverse immune response producing antibodies against a broad spectrum of RBC antigens. As patients get older, the immune response becomes more limited and usually only responds against the most immunogenic RBC antigens. In summary, these results suggest that potential responders to intravenous administration of RBCs comprise a genetically distinct group and that additional factors determine which transfusion will induce an immune response in potential responders. The factors that cause a person to be a potential responder and the factors that cause a potential responder actually respond to a specific transfusion are subjects of ongoing research. In the meantime, transfusion services may consider minimizing immunologic stimuli to patients who are clearly responders. 1. Higgins JM, Sloan SR. Stochastic modeling of human RBC alloimmunization: evidence for a distinct population of immunologic responders. Blood. 2008;112:2546-2553. Disclosures No relevant conflicts of interest to declare.
Universal fibers for data center applications

In this paper, we present a new type of optical fiber, called universal fiber, which can be used for both multimode and single mode transmissions. The fiber is a multimode fiber that has an LP01 mode field diameter approximately matched to that of standard single mode fiber. First, we will present the universal fiber design concept and discuss design tradeoffs for both single mode and multimode operations. Then we will show characterizations of a preliminary experimental fiber and present system testing results with 110 m, 150 m and 2700 m system reach using 100G SR4, 40G sWDM multimode and 100G CWDM4 single mode transceivers, respectively, which demonstrate both multimode and single mode transmission capabilities of universal fiber.
Recipient vessels for microsurgical flaps to the abdomen: A systematic review.

Background Large soft tissue defects of the abdominal wall resulting from various reasons may require free tissue transfer. Methods A literature search of PubMed and Cochrane electronic databases was conducted to identify articles involving abdominal wall reconstruction (AWR) with microsurgical flap. Number of cases, etiology, and reconstruction site, type of microsurgical flap and recipient vessels were analyzed. Results Thirty-eight articles published between 1983 and 2016 reported on 149 patients undergoing free flap AWR. TFL was used in 43 patients (28.8%), LAD in 43 (28.8%), and ALT in 28 (18.7%). Conjoined ALT and TFL flap was reported in 24 patients (16.1%). The inferior epigastric artery/vein were the most commonly utilized recipient vessels (n = 43 patients). Intraperitoneal vessels were used in 18 cases, the gastroepiploic vessels being the most common (n = 9). Femoral vessels were used directly or along with a vein graft in 14 patients. AV loop or vein graft was reported in 46 patients. Great saphenous vein rerouting was used in 8 cases. DLCF vessels were used in 2 patients to support an AV loop or directly the pedicle of a microsurgical flap. The internal thoracic vessels were used in only 3 patients. Conclusions The current review analyzed articles on AWR using microsurgical flaps with a special emphasis on the recipient vessels. The literature review demonstrated that there is no standard approach to repair a complex abdominal defect given the diversity of patient population. The choice of microsurgical flap and selection of recipient vessels should be tailored to the individual patient's circumstances.
Semantic Web Identity of Academic Libraries

AbstractSemantic Web Identity (SWI) is proposed as the condition in which search engines recognize the existence and nature of entities. The display of a Knowledge Graph Card in Google search results is an indicator of SWI, as it demonstrates that Google has gathered verifiable facts about the entity. Such recognition is likely to improve the accuracy and relevancy of Google's referrals to that entity. This article summarizes part of the research conducted for a recent doctoral dissertation, showing that SWI is poor for ARL libraries. The study hypothesizes that the failure to populate records in appropriate Linked Open Data and proprietary Semantic Web knowledge bases contributes to poor SWI.
Measuring erosion rates on exposed limestone residuum using erosion pins: a 10-year record

AbstractErosion rates in residual limestone soils in a humid climate were measured for 10 years at one site, and for 4 years at another site, using erosion pins. Erosion pins were placed in gully floors and on convex divides between adjacent gullies, on abandoned land where vegetation had been removed. We measured an average erosion rate of 20 mm yr−1 over 10 years at one site and only 5 mm yr−1 over 4 years at another site where chert gravel was common on the surface. The 10-year average erosion rate of divides (26 mm yr−1) was significantly greater than the average erosion rate of gullies (14 mm yr−1), suggesting control by different processes, some of which may be seasonal. In winter, it was observed that frost action produced a thin layer of loose soil on the surface of divides. In summer, a hardpan developed on divides, as the soil loosened by winter frosts was transported to gullies, likely by rainsplash or dry ravel. The diffusive processes of frost action, rainsplash, and dry ravel appear to shape...