cssi/SciSciGPT-SciSciNet huggingface dataset:
Abstract 58: The Quality of Prearrival Cardiopulmonary Resuscitation: A Performance Review of Regional Dispatchers and Bystanders

Background: Emergency Medical Service (EMS) dispatchers and bystanders play key roles in EMS pre-arrival cardiopulmonary resuscitation (CPR). There is, however, no standardized review process for evaluating the performance of dispatchers and bystanders. Method: We conducted a performance review of pre-arrival CPR in Nara city (276.8km2, 364,000 residents). Dispatch instruction for CPR was defined as ‘Complete Instruction’ (dispatchers recognized first compression) or ‘Incomplete Instruction’ (dispatchers failed to recognize first compression). Based on evaluation by EMS at the scene, bystander CPR continuing until EMS arrival was classified as ‘Continuous Compression’. Bystander CPR with hard and fast chest compressions was classified as ‘Good Compression’. Results: We reviewed 197 cardiac arrest calls between Nov. 2013 and Mar. 2014. CPR was already in progress in 51 cases. In the remaining 146 cases, CPR need was recognized in 129. Due to barriers preventing CPR instruction, dispatchers provided instruction in 106 cases and bystanders performed CPR in 51 cases. Among these, dispatchers provided ‘Complete Instruction’ in 33 cases and ‘Incomplete Instruction’ in 18 cases. ‘Continuous Compression’ was performed in 37 cases and significantly more often in the ‘Complete Instruction’ than the ‘Incomplete Instruction’ group (28/33[84.8%] vs 9/18[50.0%], Chi-square test p=0.008*). The median elapsed time before first compression was 145 seconds in the ‘Continuous Compression’ with ‘Complete Instruction’ group (N=28). ‘Good Compression’ was performed in only 15 cases. Conclusion: Our performance review found that ‘Complete Instruction’ was strongly associated with immediate and continuous bystander CPR until EMS arrival. Unfortunately, ‘Good Compression’ was not frequently provided. Performance reviews of both dispatchers and bystanders can yield useful information for improving the quality of pre-arrival CPR.
Screening for diabetes in an African American community: identifying characteristics associated with abnormal blood glucose readings.

Abstract Objective To identify characteristics associated with abnormal blood glucose readings among African Americans and to determine the potential value of a more targeted approach to community-based screenings for type 2 diabetes. Methods Data were collected from 7113 participants with no previous diagnosis of diabetes at mobile screening events in Detroit, Michigan. Data collected included gender, race, age, self-reported height and weight, total diabetes risk score, blood pressure, and random capillary blood glucose. Results Nearly 9% of participants had abnormal random plasma glucose readings (RPG > 160 mg/dL). Results indicated that higher age, elevated blood pressure, and body mass index (BMI) were significantly associated with abnormal glucose readings. Conclusion These findings suggest that community-based screenings for diabetes that are targeted to adults aged more than 50 years who have high blood pressure or a BMI of at least 25 may enhance detection of abnormal glucose levels among African Americans.
Asymptotic prime ideals of S2-filtrations

Abstract Let A be a noetherian ring with total ring of fractions Q ( A ) and S = ⊕ n ∈ Z I n t n a noetherian graded ring such that A [ t − 1 ] ⊆ S ⊆ Q ( A ) [ t , t − 1 ] and S satisfies the ( S 2 ) property of Serre. Under mild conditions on the ring A, we study the behavior of the sets of associated prime ideals Ass ( A / I n ∩ A ) for n ≥ 1 . In particular, we consider the case when S is the S 2 -ification of the extended Rees algebra of an ideal I. As applications, we obtain several results regarding the asymptotic behavior of Ass ( A / I n ) for certain ideals of analytic deviation one. We also prove several consequences about the symbolic powers of a prime ideal.
TYW1: A Radical SAM Enzyme Involved in the Biosynthesis of Wybutosine Bases.

Abstract Transfer RNA is extensively modified by the actions of a variety of enzymes. The radical S-adenosyl- l -methionine enzyme TYW1 modifies tRNAPhe forming the characteristic tricyclic ring via the condensation of carbons 2 and 3 of pyruvate. This chapter details methods that are required for studies of TYW1.
Multicriteria Optimization of ABS Control Algorithms Using a Quasi-Monte Carlo Method

The Quasi-Random Weighted Criteria method is proposed for multicriteria design optimization. This quasi-Monte Carlo method features increased computational efficiency and is particularly suitable for exploring alternative design configurations. A quasi-random sequence generates a set of candidate solutions representative of the range of available solutions for each design alternative. The method can be used recursively to produce more detailed Pareto surface descriptions near selected points.
Doppler Shift Frequency to Voltage Conversion Techniques

Three methods of converting the Doppler signal to voltage proportional to mean velocity are compared. The traditional zero crosser is simple and reliable, however, erroneous readings are obtained in the presence of noise and broad band Doppler signals. The more complicated analog processor technique computes the true normalized first moment of the power spectrum and offers superior performance at low velocities and in the presence of noise. A new high frequency offset technique attempts to combine the simplicity of the zero crosser and the linearity of the analog processor. The signal is shifted to a high offset (100 KC typical) where the zero crossing rate becomes an excellent approximation to the first moment.
Energy Transduction in Mitochondrial Respiration by the Proton-Motive Q-Cycle Mechanism of the Cytochrome bc1 Complex

The cytochrome bc 1 complex is an oligomeric electron transfer enzyme located in the inner membrane of mitochondria, where it participates in respiration, and the plasma membrane of bacteria, where it participates in respiration, denitrification, and nitrogen fixation (Trumpower and Gennis, 1994). The cytochrome bc 1 complex transfers electrons from ubiquinol to cytochrome c and links this electron transfer to translocation of protons across the membrane in which it resides, thus converting the available free energy of the oxidation-reduction reaction into an electrochemical proton gradient. The relationship between the cytochrome bc 1 complex, the cytochrome c oxidase complex, and some of the dehydrogenases that form the ubiquinol substrate for the cytochrome bc 1 complex is shown in Fig. 1.
Enabling Social Play: A Framework for Design and Evaluation

This chapter focuses on evaluation and design for successful social play in digital games. It includes an overview of published work in this area and best practices gleaned from professional discussions and descriptions and presents a framework for thinking about an effective evaluation and iteration process. The framework includes issues such as identifying play subgroups and how they differ, interpersonal dynamics that can and should be leveraged and looked for in multiplayer play, hardware factors in supporting social play, and issues of external validity in evaluation of social play. It includes key challenges and work that remains to be done in this area.
Xenophobia as a determinant of health: an integrative review

Though xenophobia has become increasingly relevant in today's political climate, little is known about the impact of xenophobia on health. While some studies have shown that xenophobia, in local contexts, may contribute to worse mental health outcomes, none have attempted to review the published literature to integrate these findings. This integrative scoping review examines the strength of these publications, then synthesizes their findings to provide a global perspective on xenophobia. The results show that it is not merely a political threat, but also has real, negative impact on the health of individuals and their communities. Given the multiple negative effects on individual and community health, xenophobia warrants more attention from both a public health and political perspective. Policies that promote cultural integration and understanding are essential to improving community health.
SM 01-2343 Darpi: envisioning data in a new light

The Statistics, Programming, and Economics Branch (SPEB) includes teams for Programming, Statistics, Health Economics, and Informatics. This branch is responsible for advanced economic and statistical collaborations across NCIPC programs, support for IT system development and management, center IT security compliance, and the development and maintenance of online web tools and databases. Recently, SPEB has added an interactive data visualization application and a child maltreatment return on investment calculator to the center’s Web-based Injury Statistics Query and Reporting System (WISQARS), built an online portal for secure and efficient exchange of information with external partners, and led economic and statistical analyses on key center priorities. In the future, SPEB plans to continue to modernize the IT infrastructure of WISQARS as well as increase the platform’s capacity to host additional data and tools, expand the use of the cloud for data processing and analysis, and address critical gaps in economic and data science.
Evaluating the explanatory power of theoretical frameworks on intention to comply with information security policies in higher education

Abstract Higher education institutions have invested heavily in their high-tech infrastructure to ensure the security and integrity of their information. Incompliance with information technology policies has shown to lead to mass information leaks, reputational damage and potential litigation. Little research has been conducted on the subject of employees’ compliance with such sensitive protocols. This paper presents a comprehensive theoretical model based on Theory of Planned Behavior, Protection Motivation Theory, General Deterrence Theory and Organizational Theory for predicting intentions of higher education employees' compliance with information security policies. Utilizing a survey instrument and using Structural Equation Modeling-Partial Least Squares method, this study found that perceived vulnerability, response efficacy and response cost to be the most predictive indicators that are positively associated with intentions of information security compliance among university staff and faculty. But, little support was found for the General Deterrence Theory, Theory of Planned Behavior and Organizational Theory in explaining the variance of higher education staff intentions to comply with information security policies. Results indicated that the Protection Motivation Theory provides the best theoretical framework to understand higher education employees’ behavior with respect to compliance with information security. Such results confirmed earlier empirical investigations attempting to understand the basic question of why do employees differ with respect to compliance with information security. Consistent with the prior research, severe sanctions, close management supervision, peers’ pressure and attitudes towards information security do not matter as much as perceived vulnerability and response efficacy in ensuring higher levels of intentions to comply with ISPs in organizations. The study recommends universities and colleges to invest in applied information security training for their staff, as well as for the university overall community.
MEDICAL EDUCATION; IMMERSION LEARNING; EMPATHY; NURSING HOME CARE

Introduction: At the University of New England College of Osteopathic Medicine (UNECOM), a medical student’s ability to both empathize with and understand older adults living in nursing homes is limited without first-hand experience. This case study research project required to answer the question: “What is it like for me to live the life of an older resident?” This article presents one student doctor’s experiences. Methods: Ethnographic/auto-biographic research designs were applied. A 23-year-old male osteopathic medical student was admitted into a nursing home for 10 days with a diagnosis. He was wheelchair reliant, bathed, toileted, fed pureed foods, and cared for by staff as a resident. Data were in journal format for pre-fieldwork, fieldwork, and post-fieldwork including subjective and objective reporting of observations, experiences, and resident encounters. Analyses included journal review and thematic categorization and coding through content analysis. Results: Three significant themes were identified: (1) Adaptation; (2) Communication; and (3) Loss. Being immersed in a nursing home, the student experienced the losses and challenges faced by older nursing home residents and gained perspective on creating community. This process provided the student with meaningful skills and empathy to engage with older adults with functional limitations. The data were integrated into the larger study. Conclusion: This experience imparted knowledge and challenged the student doctor’s attitudes about aging, loss, and the critical role of making meaningful connections in order to adapt to challenging circumstances. These insights provided an understanding of osteopathic care gained through immersion learning that is person-centered, comprehensive, and empathic.
The relationship between occupational physical activity and self-reported vs measured total physical activity

Abstract Introduction Despite the well-established benefits of physical activity (PA), a large portion of U.S. adults are not meeting recommended health-based guidelines. Although PA occurs in several domains, population-based studies tend to focus on leisure-time PA, with few studies examining occupational activity (OA) level as a separate determinant of overall PA. Methods Data were obtained from the 2014–2016 Survey of Health of Wisconsin (SHOW). Currently employed SHOW participants (n = 822) were categorized into OA level categories. Bivariate analyses and multinomial logistic regression analyses were used to identify predictors and to test associations between OA and odds of meeting total PA guidelines using both self-reported and accelerometer-based data. Results Individuals with high OA level jobs tended to be males (p Conclusions Correlations between low, intermediate, and high OA and levels of overall PA varied by measurement type. Further research is needed to improve PA measurements within subdomains such as OA and to examine the tradeoffs between OA and leisure-time PA and relationships with health.
Polarization of core orbitals and computation of nuclear quadrupole coupling constants using Gaussian basis sets

Most standard Gaussian basis sets for first row atoms, even large sets designed to converge on a ‘complete basis set’ limit, systematically overestimate the electric field gradient at nuclear sites for first row atoms, resulting in errors of up to 15% in the computation of nuclear quadrupole coupling constants. This error results from a failure to include tight d functions, which permit the core 1s orbitals to distort under the influence of the field of the nuclear quadrupole. Augmentation of standard basis sets with a single set of single-exponent d functions, matched to the reciprocal square of the nominal 1s radius, reduces these errors by up to 90%.
Survey of the Monitoring and Control Practices for Arthropod Pests by the Nursery Industry in Pennsylvania

Abstract The effort to encourage the nursery industry to adopt IPM practices has met with varied success. In 2000, a survey was conducted to assess the monitoring and control practices for arthropo...
Congenital Eyelid Malpositions and Anomalies

A variety of eyelid anomalies can be present at the time of birth, seen as an isolated finding or in association with systemic syndromes. These anomalies can be broadly grouped as abnormalities of eyelid division, eyelid tissue defects (colobomas), congenital eyelid malpositions, and congenital eyelid lesions. Knowledge of basic embryology of the eyelid affords a better understanding of abnormalities, especially failures of eyelid development or palpebral fissure division such as cryptophthalmos and ankyloblepharon. Colobomatous eyelids must be considered from the standpoint of their potential for syndromic association, as well as for the challenges that can be involved in repairing these tissue defects. Congenital eyelid malpositions are often functionally and cosmetically significant, requiring effective management early in life. Finally, certain eyelid lesions may be apparent at birth or manifest in the weeks or months thereafter. Lesions with amblyogenic potential must be addressed in a timelier fashion.
Between Comparison and Normativity: Scriptural Reasoning and Religious Ethics

Scriptural Reasoning (SR) is a form of interfaith dialogue that understands the logic of scriptural interpretation as a process of applying religious insights to their appropriate contexts, a process that is enhanced when members of different faith traditions interpret each other’s sacred texts together. In this chapter, I examine SR in relation to religious ethics, part of a larger project of imagining how scriptural text shapes reflection on morality. I argue that SR provides logical resources whose applications extend beyond the parameters of its own practices. SR provides what I call “logical resources,” which are certain strategies for reading texts. Such strategies not only clarify a text’s content at a surface level; they also navigate seemingly contradictory interpretations, explicate implicit background assumptions that went into the text’s composition or guide its prescriptions, and, above all, identify contexts that mediate between the text and some community of readers. These strategies can be applied to a range of texts, including scholarly works, official social and doctrinal teaching texts, as well as the Bible itself, which is the scriptural foundation for Christian ethics. In broad terms, the logic from SR that I identify can be positioned between comparison and normativity, contributing to a religious ethics that has the capacity to describe moral worlds both within and across communities, compare these worlds, identify their distinct normativities, and apply normativity itself in diagnosing and repairing the problems it uncovers.
A Reinforcement Learning Based Network Scheduler for Deadline-Driven Data Transfers

We consider a science network that runs applications requiring data transfers to be completed within a given deadline. The underlying network is a software defined network (SDN) that supports fine grain real-time network telemetry. Deadline-aware data transfer requests are made to a centralized network controller that schedules the flows by setting pacing rates of the deadline flows and metering the background traffic at the ingress routers. The goal of the scheduling algorithm is to maximize the number of flows that meet the deadline while maximizing the network utilization. In this paper, we develop a Reinforcement Learning (RL) agent based network controller and compare its performance with well-known heuristics. For a network consisting of a single bottleneck link, we show that the RL-agent based network controller performs as well as Earliest Deadline First (EDF), which is known to be optimal. We also show that the RL-agent performs significantly better than an idealized TCP protocol in which the bottleneck link capacity is equally shared among the competing flows. We also study the sensitivity of the RL-agent controller for different parameter settings and reward functions.
4 – Flame Phenomena in Premixed Combustible Gases

Publisher Summary Given a premixed fuel-oxidizer system at room temperature and ambient pressure, the mixture is essentially unreactive. However, if an ignition source applied locally raises the temperature substantially, a region of explosive reaction can propagate through the gaseous mixture. Still the condition is that the composition of the mixture is within certain limits. These limits, called flammability limits, are discussed in this chapter. When a premixed gaseous fuel-oxidizer mixture within the flammability limits is contained in a long tube, a combustion wave will propagate down the tube if an ignition source is applied at one end. In this propagating combustion wave, subsequent reaction, after the ignition source is removed, is induced in the layer of gas ahead of the flame front. This is done by two mechanisms that are closely analogous to the thermal and chain branching mechanisms. This combustion wave is normally referred to as a flame; and since it can be treated as a flow entity, it may also be called a deflagration. The chapter also discusses laminar flame structure, the laminar flame speeds, and stability limits of laminar flames. Moreover, stirred reactor theory is described here.
Keypoints for management of neonatal cytomegalovirus infection

Congenital infection of cytomegalovirus (CMV) of neonates and perinatal infection in preterm infants could be hazardous, especially for very low birth weight (VLBW) infants.Some permanent sequelae might occur in most symptomatic congenital infection and severe perinatal infection cases.However, most of the CMV infection in neonates is subclinical.It is still important to take appropriate measures to deal with different neonatal CMV infection situations.This article was focused on the epidemiology of neonatal CMV infection, clinical characteristics after infection, diagnosis of the pathogen, indications for treatment and the methods for processing the breast milk with virus. Key words: Cytomegalovirus; Infant, newborn; Very low birth weight infant; Treatment
Subtotal Gastrectomy with D2 Lymphadenectomy

Gastric cancer requires 5 cm margins when surgical resection is feasible. Only distal gastric cancers can be treated with a subtotal gastrectomy. Lymph node dissection is essential for staging and risk stratification. While there is controversy between the stations of lymph nodes that need to be removed, the present chapter describes a D2 lymphadenectomy.
Slowed Compensation Responses to Altered Auditory Feedback in Post-Stroke Aphasia: Implications for Speech Sensorimotor Integration

Developing a clearer understanding of impairments that underlie the behavioral characteristics of aphasia is essential for the development of targeted treatments and will help inform theories of speech motor control. Impairments in sensorimotor integration of speech in individuals with conduction aphasia have previously been implicated in their repetition deficits. However, much less is known about the extent to which these integrative deficits occur outside of conduction aphasia and how this manifests behaviorally in areas other than speech repetition. In this study, we aimed to address these issues by examining the behavioral correlates of speech sensorimotor impairment under altered auditory feedback (AAF) and their relationship with the impaired ability to independently correct for online errors during picture naming in people with aphasia. We found that people with aphasia generate slower vocal compensation response to pitch-shift AAF stimuli compared with controls. However, when the timing of responses was controlled for, no significant difference in the magnitude of vocal pitch compensation was observed between aphasia and control groups. Moreover, no relationship was found between self-correction of naming errors and the timing and magnitude of vocal compensation responses to AAF. These findings suggest that slowed compensation is a potential behavioral marker of impaired sensorimotor integration in aphasia.
Automated and Distributed Monte Carlo Generation for GlueX

MCwrapper is a set of systems that manages the entire Monte Carlo production workflow for GlueX and provides standards for how that Monte Carlo is produced. MCwrapper was designed to be able to utilize a variety of batch systems in a way that is relatively transparent to the user, thus enabling users to quickly and easily produce valid simulated data at home institutions worldwide. Additionally, MCwrapper supports an autonomous system that takes user’s project submissions via a custom web application. The system then atomizes the project into individual jobs, matches these jobs to resources, and monitors the jobs status. The entire system is managed by a database which tracks almost all facets of the systems from user submissions to the individual jobs themselves. Users can interact with their submitted projects online via a dashboard or, in the case of testing failure, can modify their project requests from a link contained in an automated email. Beginning in 2018 the GlueX Collaboration began to utilize the Open Science Grid (OSG) to handle a bulk of simulation tasks; these tasks are currently being performed on the OSG automatically via MCwrapper. This talk will outline the entire system of MCwrapper, its use cases, and the unique challenges facing the system.
Lynn Margulis and Boris Kozo-Polyansky: How the Symbiogenesis was translated from Russian.

Abstract This contribution details the complex history of the early work by Boris Kozo-Polyansky (1924) that became available in English translation 86 years after it was published in Russian. The great American naturalist Lynn Margulis—whose serial endosymbiosis theory was presciently predated by Kozo-Polyansky by four decades—was instrumental in organizing this resurrection and ‘horizontal transfer’ of knowledge, forgotten by that time even in Russia.
Anatomy of the posterolateral spinal epidural ligaments.

Background The epidural ligaments (ELs) (of Hofmann) were described as fibrous bands interconnecting the ventrolateral spinal dura and the posterior longitudinal ligament below L1. They are hardly ever discussed in the literature or considered in hypothesis-driven basic science experiments or spine biomechanical models. Methods Intraoperative photographs were obtained to illustrate a group of posterolateral spinal ELs. In addition, electronic database searches (PubMed, Ovid Embase, and SCOPUS) were utilized to summarize the anatomy, and relevant clinical and surgical factors impacting these ELs. Results ELs attach circumferentially at most spinal levels. They anchor the nerve root sleeves ventrally, and therefore, may play a role in the some idiopathic neurologic deficits (e.g., postoperative radiculopathies, C5 palsies) in patients without radiological compression. The posterolateral ELs originate on the dura dorsal to the nerve root sleeves and insert on the ipsilateral lamina, interlaminar ligament, and facet capsule. They appear to be continuous with the peridural membrane, a fibrovascular sheath that surrounds the thecal sac and serves as a scaffold for the internal vertebral venous plexus of Batson and epidural fat. Conclusion The spinal ELs should be divided sharply during surgery to prevent durotomies, especially in patients with advanced spondylosis and facet arthropathy. Disconnecting these ligaments releases the thecal sac laterally and ventrally, allowing for medial mobilization when performing discectomies or for working in the ventral epidural space.
Recurrent Inguinal Hernia

Hernia recurrence is an important complication of inguinal hernia repair. A complete evaluation should include information on prior repair technique and risk factors for recurrence. When the diagnosis is uncertain, imaging including ultrasound and cross-sectional modalities can be especially helpful. It is important to differentiate recurrence from other potential causes of postoperative groin symptoms. Operative approach depends on initial repair approach and technique as well as surgeon experience and expertise. In general, it is advisable to approach the hernia through a non-scarred surgical field whenever possible.
Hepatocellular carcinoma with biliary and neuroendocrine differentiation: A case report.

BACKGROUND Liver tumors with dual differentiations [combined hepatocellular carcinoma (HCC) and cholangiocarcinoma] are common. However, liver tumors that exhibit hepatocellular, biliary, and neuroendocrine differentiation are exceedingly rare, with only three previous case reports in the literature. CASE SUMMARY A 65-year-old female with a previous history of hepatitis C and a distant history of low grade, well-differentiated rectal neuroendocrine tumor was found to have two liver lesions in segment 4 and segment 7 on imaging. Serum alpha-fetoprotein and chromogranin A were elevated. Biopsy of the larger lesion in segment 4 revealed a high-grade tumor, with morphologic and immunohistochemical features of a neuroendocrine tumor. Given the previous history of rectal neuroendocrine tumor, imaging investigation, serologic markers, and biopsy findings, metastatic neuroendocrine tumor was considered. Subsequent regional resection of these hepatic lesions revealed the segment 4 lesion to be a HCC with additional biliary and neuroendocrine differentiation and the segment 7 lesion to be a cholangiocarcinoma with neuroendocrine differentiation. Follow-up of the patient revealed disease recurrence in the dome of the liver and metastasis in retro-pancreatic lymph nodes. The patient eventually expired due to complications of chemotherapy. CONCLUSION HCC cases with additional biliary and neuroendocrine differentiation are exceedingly rare, posing a diagnostic challenge for clinicians and pathologists.
Thirty-day hospital readmission rate, reasons, and risk factors after acute inpatient cancer rehabilitation.

OBJECTIVES To evaluate the 30-day hospital readmission rate, reasons, and risk factors for patients with cancer who were discharged to home setting after acute inpatient rehabilitation. DESIGN, SETTING, AND PARTICIPANTS This was a secondary retrospective analysis of participants in a completed prospective survey study that assessed the continuity of care and functional safety concerns upon discharge and 30 days after discharge in adults. Patients were enrolled from September 5, 2018, to February 7, 2020, at a large academic quaternary cancer center with National Cancer Institute Comprehensive Cancer Center designation. MAIN OUTCOMES AND MEASURES Thirty-day hospital readmission rate, descriptive summary of reasons for readmissions, and statistical analyses of risk factors related to readmission. RESULTS Fifty-five (21%) of the 257 patients were readmitted to hospital within 30 days of discharge from acute inpatient rehabilitation. The reasons for readmissions were infection (20, 7.8%), neoplasm (9, 3.5%), neurological (7, 2.7%), gastrointestinal disorder (6, 2.3%), renal failure (3, 1.1%), acute coronary syndrome (3, 1.1%), heart failure (1, 0.4%), fracture (1, 0.4%), hematuria (1, 0.4%), wound (1, 0.4%), nephrolithiasis (1, 0.4%), hypervolemia (1, 0.4%), and pain (1, 0.4%). Multivariate logistic regression modeling indicated that having a lower locomotion score (OR = 1.29; 95% CI, 1.07-1.56; p = 0.007) at discharge, having an increased number of medications (OR = 1.12; 95% CI, 1.01-1.25; p = 0.028) at discharge, and having a lower hemoglobin at discharge (OR = 1.31; 95% CI, 1.03-1.66; p = 0.031) were independently associated with 30-day readmission. CONCLUSION AND RELEVANCE Among adult patients with cancer discharged to home setting after acute inpatient rehabilitation, the 30-day readmission rate of 21% was higher than that reported for other rehabilitation populations but within the range reported for patients with cancer who did not undergo acute inpatient rehabilitation.
Abstract A29: A tale of two diverse Qualtrics samples: Information for online survey researchers

Background: Online recruitment and sampling can be particularly effective in targeting specific groups. The use of quota sampling (i.e., the nonrandom sampling of individuals belonging to a specific subgroup) in online panel research can help researchers obtain survey participants matching a specific condition of interest to the researcher. Despite the advantages of online samples, many researchers are either unaware of or skeptical about the use of online panels for sample acquisition. Purpose: The purpose of this study was to describe the recruitment and respondent characteristics of two disparate samples derived from online panels for survey research. This information is needed to inform researchers on what to expect when administering an online survey and recruiting participants through a commercial research platform. Methods: A commercial survey sampling and administration company, Qualtrics, was contracted to recruit participants and implement two Internet-based surveys. The first survey targeted adults aged 50-75 years old. This survey utilized sampling quotas to obtain a sample that was diverse with respect to household income and race. The comparison study focused on women aged 18-49 years and used quota sampling to help achieve a geographically balanced sample. The two surveys were approximately equivalent in terms of survey duration and participant remuneration. Results: Although each survey recruited the desired number of respondents within a relatively short period of time, differences in the participant flow were observed between studies. Recruitment of the older adult sample took longer than the study focused on young adult women. Differences in the variables related to sampling quotas were also significant. Furthermore, the proportions of respondents who initiated, completed, screened out, failed a quality check, and failed to complete the survey were inconsistent across studies. Conclusion: Results of this novel research have important implications for the development of future online surveys using samples recruited from online panels. Conclusions provide practical guidance related to Internet survey design and recruitment procedures. Citation Format: Carrie A. Miller, Jeanine Guidry. A tale of two diverse Qualtrics samples: Information for online survey researchers [abstract]. In: Proceedings of the AACR Special Conference on Modernizing Population Sciences in the Digital Age; 2019 Feb 19-22; San Diego, CA. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2020;29(9 Suppl):Abstract nr A29.
Exercise intervention decreases acute and late doxorubicin-induced cardiotoxicity

Background Doxorubicin (Dox) is one of the most effective chemotherapy agents used to treat adolescent and young adult sarcoma patients. Unfortunately, Dox causes cardiotoxicities that compromise long-term survival. We investigated whether exercise prevented cardiotoxicity and increased survival following myocardial infarction. Methods Juvenile mice received Dox, Dox + exercise (Exer), Dox then exercise or were exercised during and after Dox. Mice were evaluated by echocardiography and histology immediately after therapy and 12 weeks later. Mice subjected to permanent ligation of the left anterior descending artery 90 days after therapy were assessed for survival at 45 and 100 days. Results Mice treated with Dox, but not Dox + Exer, had decreased ejection fraction (EF) and fractional shortening (FS) immediately after Dox therapy, which continued to deteriorate over 12 weeks with the development of diastolic failure and fibrosis. Acute Dox-induced cardiotoxicity was documented by induction of autophagy and abnormal mitochondria and vascular architecture with decreased pericytes. These abnormalities persisted 12 weeks after therapy. These acute and late changes were not seen in the Dox + Exer group. Initiating exercise after Dox therapy promoted recovery of EF and FS with no functional or histologic evidence of Dox-induced damage 12 weeks after therapy. Survival rates at 100 days after MI were 67% for control mice, 22% for mice that received Dox alone, and 56% for mice that received Dox + Exer. Conclusions Exercise inhibited both early and late Dox-induced cardiotoxicity and increased recovery from an ischemic event. Exercise interventions have the potential to decrease Dox-induced cardiac morbidity.
The Brothers Grimm and the Making of German Nationalism

In the first comprehensive English-language portrait of Jacob and Wilhelm Grimm as political thinkers and actors, Jakob Norberg reveals how history's two most famous folklorists envisioned the role of literary and linguistic scholars in defining national identity. Convinced of the political relevance of their folk tale collections and grammatical studies, the Brothers Grimm argued that they could help disentangle language groups from one another, redraw the boundaries of states in Europe, and counsel kings and princes on the proper extent and character of their rule. They sought not only to recover and revive a neglected native culture for a contemporary audience, but also to facilitate a more harmonious and enduring relationship between the traditional political elite and an emerging national collective. Through close historical analysis, Norberg reconstructs how the Grimms wished to mediate between sovereigns and peoples, politics and culture.
Nanosecond fluorescence resonance energy transfer‐fluorescence lifetime imaging microscopy to localize the protein interactions in a single living cell

Visualizing and quantifying protein-protein interactions is a recent trend in biomedical imaging. The current advances in fluorescence microscopy, coupled with the development of new fluorescent probes such as green fluorescent proteins, allow fluorescence resonance energy transfer (FRET) to be used to study protein interactions in living specimens. Intensity-based FRET microscopy is limited by spectral bleed-through and fluorophore concentration. Fluorescence lifetime imaging (FLIM) microscopy and lifetime measurements are independent of change in fluorophore concentration or excitation intensity, and the combination of FRET and FLIM provides high spatial (nanometre) and temporal (nanoseconds) resolution. Because only the donor fluorophore lifetime is measured, spectral bleed-through is not an issue in FRET-FLIM imaging. In this paper we describe the development of a nanosecond FRET-FLIM microscopy instrumentation to acquire the time-resolved images of donor in the presence and the absence of the acceptor. Software was developed to process the acquired images for single and double exponential decays. Measurement of donor lifetime in two different conditions allowed us to calculate accurately the distance between the interacting proteins. We used this approach to quantify the dimerization of the transcription factor CAATT/enhancer binding protein alpha in living pituitary cells. The one- and two-component analysis of the donor molecule lifetime in the presence of acceptor demonstrates the distance distribution between interacting proteins.
Hazard analysis and critical control point programs for raw oyster processing and handling.

Abstract: Bivalve molluscs such as oysters destined for raw consumption share the common problem of potential microbial and chemical contamination of the edible portion of the product due to the natural filtration of surrounding waters that provide essential oxygen and food. This chapter reviews SSOP and HACCP programs for the safe handling of raw oysters
Education, Families, and Workplace Policies

ECONOMISTS, cliche that the United States is in the midst of transitioning from an industrial economy to one that is knowledge-based. The general argument is that for the United States to compete and maintain high standards of living in a global economy, it needs a welleducated, motivated, and innovative workforce that is employed in organizations that treat workers' knowledge and skills as assets and sources of competitive advantage rather than just as costs to be controlled. Comparing families that got ahead to those that did not in recent years demonstrates that this transition is more than a cliche. What is
Sweet's syndrome without granulocytosis

Background Sweet's syndrome (SS), acute febrile neutrophilic dermatosis, has been linked to hematologic malignancies and presents with characteristic edematous dermal plaques. Peripheral blood neutrophilia is frequently seen in association with SS and is one of the diagnostic criteria. Objective To report the clinical, laboratory, and hematologic data of four patients with myeloid leukemia who developed SS after chemotherapy. Three of these patients were neutropenic. Methods A retrospective study of four patients with SS and hematologic malignancies was undertaken. Three patients had de novo acute myelogenous leukemia and one was in the acute blast crisis of chronic myelogenous leukemia. ResultsSweet's syndrome was not originally suspected in these patients because of the low peripheral white blood cell counts caused by chemotherapy. All of the patients presented with fevers, arthralgias, and an eruption. They had been treated with antibiotics because of a presumed infection. Once the correct diagnosis was made and oral prednisolone was started, a rapid response followed. ConclusionsSweet's syndrome should be considered in the differential diagnosis when acute myeloid leukemic patients develop skin lesions and unexplained fevers regardless of the peripheral blood counts.
Balance Conditions in the Earth'S Climate System

Publisher Summary This chapter elaborates the balance conditions in the earth's climate system. The oceans play a central role in handing over angular momentum from the atmosphere to the land masses. A useful way of diagnosing the climatic system is through the analysis of the cycles of angular momentum, water substance, and energy. It is found that through the analysis of the pathways of these three central and very distinct physical quantities, the inter-relationships among the various climatic subsystems become clearer. The observed cycle of relative angular momentum computed from direct wind observations in the atmosphere is presented in this chapter. Westerly angular momentum is extracted from the Earth's surface in the tropics, transported upward in the tropical Hadley cells, then transported poleward in the upper troposphere, and finally returned down to the Earth's surface in the middle latitudes. The energy balance in the terrestrial branch of a latitudinal belt extending throughout the depth of the ocean is also examined.
Obstacle avoidance using neural networks

A neural network that limits the closest point of approach of an autonomous underwater vehicle (AUV) with respect to a navigation obstacle is described. Neural network inputs consist of beam outputs from a forward-looking sonar, and differences between current and desired values for AUV course and speed are inputs to normal navigation and control. The neural network outputs are AUV rudder angle and propulsion power: basic vehicle maneuvering characteristics are incorporated in the model. Obstacle avoidance is accomplished using a proximity detector for avoiding static obstacles and a rate detector for avoiding moving obstacles. The detections are made using 2D masked binary filters implemented as multilayer neural networks in the classification mode. Adaptive training is not used: instead. neuron weights are defined by the desired AUV response. The AUV simulation successfully avoided collision with all obstacles during test runs. >
Privilege or Punish: Criminal Justice and the Challenge of Family Ties

Introduction Part I: The Challenge of Family Ties Benefits Intersections Between Family and the State's Criminal Justice System A Framework for Analyzing Family Ties Benefits Applying the Spartan Presumption to Family Ties Benefits Part II: The Challenge of Family Taxes Sites of Familial Taxes A Framework For Family Taxes Evaluating the Case Against Family Taxes Index
Explaining Legislative Productivity: Evaluating the Effects of Polarization and Divided Government In a Cross-Sectional Study of State Legislatures

Despite a wealth of literature on the causes of gridlock in Congress, there is a lack of comparative work at the state level exploring whether lawmaking in state legislatures functions similarly. Operating under a theoretical framework assuming polarization and divided government are the primary obstacles to legislative success, and controlling for majority seat share, I test the determinants of legislative productivity with an original dataset consisting of 31 states. I operationalize legislative productivity using a content analysis of editorials from each state during the 2009-2010 legislative sessions to identify pressing political issues, and then determine how many of these issues were addressed in some form of legislation during this period. Utilizing an improved measure of legislative productivity that weights issues by salience, I find that polarization's effects on productivity are conditioned by the presence or absence of divided government; during instances of unified government, polarization increases productivity, while this effect is negated under divided government. INTRODUCTION In recent years, much has been written about the failure of the political system to simply get things done. The high profile government shutdown of 20 13, budgetary fighting and delays in state legislatures, and an increasingly hostile partisan atmosphere have all contributed to what has been characterized in the media as a political crisis. As a 2013 op-ed in the New York Times puts it, "the legislature has ceased to function" and claims that "what we're losing in the process isn't government -it's democracy". 1 While such claims might appear to be dramatized, they do point to a current lack of understanding about when and why government is successfully able to pass laws. What makes some legislatures effective and leaves others mired in gridlock? Political science literature has grappled with this question for almost 130 years, dating back to Woodrow Wilson's critical examination of the nation's primary legislature, Congressional Government. Despite the passage of time, a consensus has failed to emerge on the causes of political gridlock, despite a wealth of recent literature attempting to tackle the topic at the national level. 2 There are numerous potential explanations, which include the effects of increasing polarization, 1 Reich 2013, A23 2 Mayhew 1991; Fiorina 1992; Binder 1999; Jones 2001; Edwards et al. 1997; McCarty et al. 2007; Ilderton 2008
Acute cocaine-induced hepatotoxicity with features of shock liver

Background: Cocaine-induced toxicity has been described to be associated with severe adverse clinical health outcomes, affecting multiple organs systems with very limited clinical recommendations or guidelines for management of some of its associated complications. Case report: We present a case of middle-aged female with acute severe hepatotoxicity after ingestion of alcohol and non-intravenous cocaine. She had markedly elevated liver enzymes and lactate dehydrogenase suggestive of shock liver but with minimal overt systemic manifestations. Patient was managed conservatively with intravenous fluids and treatment of con-current co-morbidities and liver enzymes and lactate dehydrogenase declined rapidly over a 5-day hospital course. Discussion: We hypothesize that cocaine may play a role in diminishing hepatic perfusion, mimicking an ischemic hepatitis type clinical presentation and suggest that similar management, based on volume resuscitation, will potentially be more helpful than harmful for patient’s presenting with acute cocaine-induced liver injury.