cssi/SciSciGPT-SciSciNet huggingface dataset:
Standards of Justice for Human Being and Doing in Kim Stanley Robinson’s 2312 and C. S. Friedman’s This Alien Shore

The creation of superior societies and communities in which bodies live better and thrive depends on richly detailed accounts of imagined societies including flexible theories of justice that can be used to evaluate them. Both Kim Stanley Robinson’s 2312 (2012) and C. S. Friedman’s This Alien Shore (1998) attempt to rethink what bodies can do and be, by exploring ways of living together among those with different, and differently compatible, bodies. The novels are set in future spacefaring societies away from the Earth, which nevertheless struggle with the fact of Earth’s existence. Each novel describes radical cognitive and bodily change: chosen alteration in 2312 and environmental transformation in This Alien Shore. In each novel, the body, and what bodies can do and be, is a central issue. But how might we evaluate the societies these novels describe to gauge their contributions to articulating desires for a better way of being? In this article I employ Martha Nussbaum’s ‘capabilities approach’ (encompassing life, bodily health, bodily integrity, senses, emotions, reason, affiliation, play, other species, control over environment) to think about justice in the articulation of evaluative standards. In so doing the analysis I develop addresses some key questions raised by these novels, including: Whose body will matter? Will there be bodily norms? How will communities confront different bodily abilities? How can we enhance our own thinking about how to live in and among bodies? How does (and should) the idea of the body politic change when our expectations about bodies changes?
Prevalência das complicações da diabetes mellitus no ACeS Santo Tirso/Trofa: estudo descritivo

Objectives: To estimate the prevalence of complications of diabetes in patients treated in the Santo Tirso/Trofa Group of Health Centers. Study type: A cross-sectional study. Setting: Santo Tirso/Trofa Group of Health Centers. Participants: Type 1 and 2 diabetic patients. Methods: A sample of the type 1 and 2 diabetic patients was randomly selected from the population registered in the health units of the Group of Health Centers in December of 2014 (N=9,426). Data were collected from electronic medical records of the patients selected. The following complications were studied: coronary heart disease, cerebrovascular disease, nephropathy, neuropathy, amputation of the lower limb and retinopathy. Data analysis was performed using SPSS® 21 and Excel® 2010 software. Results: Of the 1,507 diabetics studied, 95.5% were type 2, 50.7% were male and the average age was 65.7±12 years. Complications were identified in 33.6% of diabetics. Nephropathy had the highest prevalence (17.2%) and amputation (0.9%) the lowest prevalence. Type 1 diabetics had a significantly higher prevalence of nephropathy, neuropathy, retinopathy and amputation. Conclusions: The prevalence of some complications found in this study was different from that found in other studies. Interpretation of these discrepancies requires care, given the possible differences between the criteria used for the diagnosis of complications. This study has characterized this problem at local level. The results obtained may be useful for future study of complications of diabetes.
Rhenium tricarbonyl complexes of AIE active tetraarylethylene ligands: tuning luminescence properties and HSA-specific binding

The synthesis and photophysical properties of luminescent Re(i) tricarbonyl complexes prepared from bis(pyridyl)- and bis(quinolyl) tetraarylethylene (TAE) ligands are reported. Emission wavelengths of the complexes are influenced by structural variation in the tetraarylethylene ligands, and several complexes display aggregation-induced enhanced emission in aqueous solution. A Re(i) complex prepared from an indole-functionalized TAE ligand shows significant enhancement in its luminescence intensity accompanied by a remarkable blue shift (∼95 nm) upon specific binding to site II of human serum albumin.
Support of distributed ecological experiments via closed-loop environmental control

Improved understanding of the effects of climate and weather patterns on plant survival and growth is critical for improving management of wildland, rangeland, and crop ecosystems. The Southwest Experimental Garden Array (SEGA) is a distributed research instrument comprising of an array of 10 common gardens across an elevational gradient in Northern Arizona. SEGA's cyber infrastructure facilitates monitoring and control of soil moisture at experimental plots using drip irri­gation and wireless sensor/actuator nodes. This paper describes development of software-based workflows for the sensing and control of soil moisture conditions across experimental plots and gardens with different temperature and rainfall regimes, and the necessary hardware and software infrastructure to support this capability.
On left-to-right arithmetic

Doing arithmetic most significant digits first (left-to-right, or MSDF) provides opportunities to circumvent or reduce data dependencies in recursive computations. It also enables digit-level massive parallelism, and allows variable precision computations with unbiased truncation. Moreover, there are benefits at the design level: precision-independent cycle time, lower energy since digits are used only when needed, and minimal interconnection. We present a view of left-to-right arithmetic features and highlight its use in solving linear systems of equations and inner-product designs.
ASNI: Attenuated Signature Noise Injection for Low-Overhead Power Side-Channel Attack Immunity

Computationally-secure cryptographic algorithms implemented on a physical platform leak significant “ side-channel ” information through their power supplies. Correlational power attack is an efficient power side-channel attack (SCA) technique, which analyzes the statistical correlation between the estimated and the measured supply current traces to extract the secret key. The existing power SCA countermeasures are mainly based on reducing the SNR of the leaked information, power balancing, or gate-level masking, each of which introduces significant power, area or performance overheads, which calls for an efficient generic countermeasure. This paper presents ASNI: Attenuated Signature Noise Injection , which is an energy-efficient generic countermeasure, and shows SCA resistance on the AES-128 encryption as an application. ASNI uses a shunt low-drop-out (LDO) regulator to suppress the AES current signature by ${>}200 \times $ in the supply current traces. The shunt LDO has been fabricated and validated in 130 nm CMOS technology. System-level implementation of the ASNI, with the AES-128 core operating at 40 MHz, shows that the system remains secure even after 1 M encryptions, with $\sim 25 \times $ reduction in power overhead compared to that of noise addition alone.
OPERATING RESULTS FOR A SOLAR COOLING SYSTEM USING A COMBINED SINGLE-DOUBLE EFFECT ABSORPTION CHILLER

ABSTRACT In order to reduce auxiliary energy consumption in a active solar cooling system, a newly developed CSDE absorption chiller was used for an actual solar system. The operating characteristics of the CSDE chiller were tested for one year in 1984 by substituting it for an existing single effect absorption chiller that had been operating for two years in 1983 and in 1982. The results shows that the CSDE absorption chiller used only 57% of auxiliary energy required by ordinary system in 1983 and only 53% of that used in 1982. The COP of the CSDE chiller in an actual operation was 0.727 and the calculated value from the distribution of operating hours for each mode was 0.82. The actual value of COP was smaller than the calculated value, but in the improved system P.S increased to 54.1% from 38.3% in 1983 and from 29.8% in 1982.
Association Between 24-Hour Intraocular Pressure Monitored With Contact Lens Sensor and Visual Field Progression in Older Adults With Glaucoma.

Importance Twenty-four–hour intraocular pressure (IOP) patterns may provide more information regarding rates of visual field progression than office-hour measurements. However, little is known about the added value of 24-hour monitoring when stratifying glaucoma risk based on rates of progression. Objective To test the hypothesis that 24-hour IOP-related patterns recorded with a contact lens sensor (CLS) correlate with prior rates of visual field progression. Design, Setting, and Participants A multicenter, retrospective cohort study was conducted at 50 ophthalmology care centers in 13 countries. Participants included 445 patients (445 eyes) with treated, manifest open-angle glaucoma. The study was conducted from November 8, 1999, to September 17, 2016. Interventions Twenty-four–hour recordings of IOP-related patterns were prospectively collected with a CLS system. Retrospective visual field data of patients who underwent at least 3 prior reliable visual field tests were examined. Main Outcomes and Measures Association between CLS variables and rates of visual field mean deviation (MD) change. Results Of the 445 patients included, 238 (53.5%) were women and 394 (88.5%) were white. The mean (SD) age and MD values at the time of CLS recording were 68.9 (11.2) years and −9.0 (7.0) dB. The mean rate of MD change was −0.46 (0.5) dB/y in 5.2 (3) years of follow-up. After adjusting for baseline MD severity, age, and treatment, the following CLS variables were associated with fast visual field progression: mean peak ratio while awake (β = −0.021; 95% CI, −0.04 to −0.003), number of long peaks during sleep (β = 0.036; 95% CI, 0.005 to 0.067), night bursts ocular pulse frequency SD (β = 0.027; 95% CI, 0.004 to 0.051), and night bursts ocular pulse amplitude SD (β = 19.739; 95% CI, 1.333 to 38.145). Regression models including CLS variables had better fit than Goldmann IOP when testing the association with rates of progression. Conclusions and Relevance Results of this study indicate that 24-hour CLS recordings may be associated with prior rates of visual field progression of glaucoma. This association appears to be better than Goldmann mean IOP measured multiple times during office hours. Therefore, the CLS may be useful to assess the risk of future functional loss, even in situations when insufficient historical visual field information is available.
Active Background Reduction with Electron Cyclotron Resonance

To alleviate or potentially eliminate the background problem arising from stored electrons in the main spectrometer, a novel method needs to be implemented that actively reduces the background by removing the stored electrons.
Efficacy of Greater Occipital Nerve Block with or without Bupivacaine in Chronic Migraineurs (P01.089)

OBJECTIVE: We conducted a retrospective comparison of migraine patients who received greater occipital nerve block (GONB) with or without bupivacaine at a neurology community clinic. BACKGROUND: Bupivacaine is a longer acting local anesthetic as compared to lidocaine. Both these local anesthetic are routinely used in greater occipital nerve block (GONB) in patients with chronic migraineurs. DESIGN/METHODS: We conducted a retrospective analysis of chronic migraineurs who received GONB at a single community neurology clinic. Patients were grouped into Group A, those who received lidocaine 1% with triamcinolone 40 mg and Group B those who received lidocaine 1%, bupivacaine 0.25% and triamcinolone 40 mg from May 2012 to August 2012. Following data was extracted: demographics, medical history, medications, visual analogue scale (VAS) before and after the GONB, duration of pain relief immediately after GONB and side effects from GONB. RESULTS: Fifteen patients with chronic migraine had their first GONB done between May-August 2012 at our neurology clinic. Seven patients were in group A (6F;1 M; AVG Age: F- 34.8 years, M-55 years) and eight patients were in group B (5F; 3M; Avg age F :39.6 years; M 56.6 years). VAS avg prior to GONB in group A was 6.4 and 6.75 in group B. VAS avg after GONB was 6.4 in group A and 5. 87 in group B. Duration for pain relief after GONB was 23.7days (Range 1-90 days) in group A and 22.6 days (range 4-90 days) in group B. All patients tolerated the procedure fairly well except one in group A who had transient dizziness. CONCLUSIONS: Greater occipital nerve block is a safe procedure used for the treatment of migraine headache. In our preliminary data, we did not find any difference in the duration of pain relief after GONB with or without bupivacaine. Prospective studies with larger sample size are needed. Disclosure: Dr. Siddiqui has nothing to disclose. Dr. Caplinger has nothing to disclose.
Environmental Effects on the Detection of Errors in Software Systems

It is very important for software developers to thoroughly test their software. Since programs are tested in a specific environment, however, some errors are difficult, if not impossible, to detect by traditional testing methods such as path analysis. A program may contain errors that are masked by the environment in which it was developed and tested. One such element in a program’s environment is the value to which memory is initialized. Mistakes in initialization would not appear until the software is ported to an environment in which memory has a different initialization value, when the software would mysteriously stop working correctly.
Anxiety: Stress, Foreign Language Classroom Anxiety, and Enjoyment During Study Abroad in Amman, Jordan

Anxiety is among the most frequently studied emotions in second language acquisition (SLA). Study abroad (SA) researchers have examined its effects on SLA in that setting in a number of studies. The current study goes beyond previous SA research by examining how anxiety develops and connects with language proficiency development over SA. Specifically, it uses anxiety-related measures of foreign language classroom anxiety (FLCA), foreign language enjoyment (FLE), and a physiological manifestation of anxiety (hair cortisol). As far as the classroom is concerned, learners grew more comfortable, experiencing less anxiety and more enjoyment over the period of SA. However, learners showed physiological signs of overall elevated anxiety despite these increasing classroom comfort levels. Two key factors that may have influenced their anxiety levels abroad were tendency toward anxiety prior to SA and language proficiency upon departure for SA. The latter provides support for having students more proficient prior to SA, since doing so may lead to less anxiety during SA.
A First Step Towards NLP from Digitized Manuscripts: Virtual Restoration

Digitization of the documental heritage conserved in libraries and archives is a common practice, in order to ensure the preservation and fruition of this extended part of the human cultural and historical patrimony. For the most precious, fragile and difficult to read and decipher manuscripts, specialized though portable digitization equipment, such as high resolution multispectral/hyperspectral cameras, is nowadays available. Digitization made it possible the increasingly extensive use of digital image processing techniques, to perform a number of virtual restoration tasks, which constitute a first, often necessary step prior subsequent automatic analysis of the writing contents, with the ultimate goal to perform automatic transcription and/or natural language processing tasks. Here we report our experience in this field, referring, as a case study, to the problem of removing one of the most frequent and impairing degradation affecting many ancient manuscripts, i.e., the bleed-through distortion. In this case, virtual restoration gives also the immediate benefit to facilitate the work of philologists and paleographers interested in examining and transcribing the manuscript in a traditional way.
An Examination of Administrators' Nonrevenue, Olympic Program Values within NCAA Athletic Departments

The presence of the arms race in intercollegiate athletics has led to extensive spending on major, revenue-producing sports (Knight Commission, 2004). Despite the fact that only a handful of men’s basketball and football programs produce profits (NCAA, 2009), administrators continue to embrace a commercial model that has coincided with the elimination of nonrevenue, Olympic sports in National Collegiate Athletic Association (NCAA) athletic departments. With this in mind, the purpose of the study was to gain an understanding of the nonrevenue, Olympic program elements that were most highly valued by NCAA Division I, II, and III athletic administrators (N = 435) to facilitate an effort to develop strategic measures to counter program discontinuation. Despite small differences in divisional responses, the results supported the existence of institutional isomorphism when unified program values (e.g., academics, conduct, community involvement) were consistent across all NCAA divisions.
Do People Want to Be More Moral

Most people want to change some aspects of their personality, but does this phenomenon extend to moral character and to close others? Targets (n = 800) rated their personality traits and reported how much they wanted to change on each trait; well-acquainted informants (n = 958) rated targets' personality traits and how much they wanted the targets to change on those same traits. Targets and informants reported a lower desire to change more morally relevant traits (e.g., honesty, compassion, fairness) compared with less morally relevant traits (e.g., anxiety, sociability, productiveness)-even after we controlled for current trait levels. Moreover, although targets generally wanted to improve more on traits that they had less desirable levels of, and informants wanted their targets to improve more on those traits as well, targets' moral change goals were less calibrated to their current trait levels. Finally, informants wanted targets to change in similar ways, but to a lesser extent, than targets themselves did. These findings suggest that moral considerations take a back seat when it comes to self-improvement.
Perceived stress is associated with a higher symptom burden in cancer survivors

Background Although multiple co-occurring symptoms are a significant problem for cancer survivors, to the authors' knowledge little is known regarding the phenotypic characteristics associated with a higher symptom burden. The objectives of the current study were to evaluate the occurrence, severity, and distress associated with 32 symptoms and examine the phenotypic and stress characteristics associated with a higher symptom burden. Methods A total of 623 cancer survivors completed a demographic questionnaire, as well as measures of functional status, comorbidity, and global (Perceived Stress Scale) and cancer-related (Impact of Event Scale-Revised) stress. The Memorial Symptom Assessment Scale was used to evaluate symptom burden. Multiple linear regression analysis was used to determine the phenotypic characteristics associated with a higher symptom burden. Results The mean number of symptoms was 9.1 (±5.2). The most common, severe, and distressing symptoms were lack of energy, problems with sexual interest/activity, and hair loss, respectively. Poorer functional status, a higher level of comorbidity, and a history of smoking as well as higher Perceived Stress Scale and Impact of Event Scale-Revised scores were associated with a higher symptom burden. The overall model explained approximately 45.6% of the variance in symptom burden. Conclusions Although cancer survivors report a high number of co-occurring symptoms of moderate severity and distress, in the current study, no disease or treatment characteristics were found to be associated with a higher symptom burden. Clinicians need to assess for general and disease-specific stressors and provide referrals for stress management interventions. Future studies need to examine the longitudinal relationships among symptom burden, functional status, and level of comorbidity, as well as the mechanisms that underlie the associations between stress and symptom burden.
Stigma, trauma and sexuality: the experiences of women hospitalised with serious mental illness

Women with serious mental illness (SMI) occupy a social position in which their experiences are simultaneously influenced by stigmatisation, institutionalisation and gendered dimensions of trauma and power. Women with SMI are stigmatised in society, pushed to the margins and left vulnerable to victimisation and rejection, particularly if hospitalised in psychiatric institutions. Using modified labelling theory, I investigate how women hospitalised with SMI, especially those who have histories of sexual abuse and trauma, experience sexuality and perceive men and masculinity. I extend modified labelling theory by empirically analysing the role of social status and power in the labelling process. Specifically, I focus on gender, and analyse interviews with 55 women in US psychiatric hospitals, focusing on gendered experiences of trauma, stigma and attitudes about sexuality. I show how trauma increases the salience of stigma and potential for retraumatisation, both of which are amplified by the institutional setting. I find meaningful differences in the narratives of women who have experienced trauma and those who have not. Modified labelling theory helps explain how labelling can perpetuate self-stigma, which threatens women's self-esteem, safety and trust in others. The intersection of these experiences extends modified labelling theory and may have profound implications for recovery.
Barriers and facilitators to implementing changes in opioid prescribing in rural primary care clinics

Background: Opioids are more commonly prescribed for chronic pain in rural settings in the USA, yet little is known about how the rural context influences efforts to improve opioid medication management. Methods: The Six Building Blocks is an evidence-based program that guides primary care practices in making system-based improvements in managing patients using long-term opioid therapy. It was implemented at 6 rural and rural-serving organizations with 20 clinic locations over a 15-month period. To gain further insight about their experience with implementing the program, interviews and focus groups were conducted with staff and clinicians at the six organizations at the end of the 15 months and transcribed. Team members used a template analysis approach, a form of qualitative thematic analysis, to code these data for barriers, facilitators, and corresponding subcodes. Results: Facilitators to making systems-based changes in opioid management within a rural practice context included a desire to help patients and their community, external pressures to make changes in opioid management, a desire to reduce workplace stress, external support for the clinic, supportive clinic leadership, and receptivity of patients. Barriers to making changes included competing demands on clinicians and staff, a culture of clinician autonomy, inadequate data systems, and a lack of patient resources in rural areas. Discussion: The barriers and facilitators identified here point to potentially unique determinants of practice that should be considered when addressing opioid prescribing for chronic pain in the rural setting.
Direct measurement of atrioventricular valve regurgitant jets using 4D flow cardiovascular magnetic resonance is accurate and reliable for children with congenital heart disease: a retrospective cohort study.

3D-time resolved flow (4DF) cardiovascular magnetic resonance (CMR) with retrospective analysis of atrioventricular valve regurgitation (AVVR) allows for internal validation by multiple direct and indirect methods. Limited data exist on direct measurement of AVVR by 4DF CMR in pediatric congenital heart disease (CHD). We aimed to validate direct measurement of the AVVR jet as accurate and reliable compared to the volumetric method (clinical standard by 2D CMR) and as a superior method of internal validation than the annular inflow method. We identified 44 consecutive patients with diverse CHD referred for evaluation of AVVR by CMR. 1.5 T or 3 T scanners, intravenous contrast, and a combination of parallel imaging and compressed sensing were used. Four methods of measuring AVVR volume (RVol) were used: volumetric method (VOL; the clinical standard) = stroke volume by 2D balanced steady-state free precession – semilunar valve forward flow (SLFF); annular inflow method (AIM) = atrioventricular valve forward flow [AVFF] – semilunar valve net flow (SLNF); and direct measurement (JET). AVFF was measured using static and retrospective valve tracking planes. SLFF, SLNF, AVFF, and JET were measured by 4DF phase contrast. Regurgitant fraction was calculated as [RVol/(RVol+SLNF)]× 100. Statistical methods included Spearman, Wilcoxon rank sum test/Student paired t-test, Bland Altman analysis, and intra-class coefficient (ICC), where appropriate. Regurgitant fraction by JET strongly correlated with the indirect methods (VOL and AIM) (ρ = 0.73–0.80, p < 0.001) and was similar to VOL with a median difference (interquartile range) of − 1.5% (− 8.3–7.2%; p = 0.624). VOL had weaker correlations with AIM and JET (ρ = 0.69–0.73, p < 0.001). AIM underestimated RF by 3.6–6.9% compared to VOL and JET, p < 0.03. Intra- and inter- observer reliability were excellent for all methods (ICC 0.94–0.99). The mean (±standard deviation) inter-observer difference for VOL was 2.4% (±5.1%), p < 0.05. In a diverse cohort of pediatric CHD, measurement of AVVR using JET is accurate and reliable to VOL and is a superior method of internal validation compared to AIM. This study supports use of 4DF CMR for measurement of AVVR, obviating need for expert prospective prescription during image acquisition by 2D CMR.
Atraumatic, Progressive, and Painful Elbow Contracture From a Ganglion Cyst

Ganglion cysts are benign soft tissue tumors that often occur adjacent to joints or tendons. We report a case of an elbow joint ganglion cyst in a patient who presented with a painful, progressive elbow contracture. The patient was successfully treated with resection of the subbrachialis ganglion cyst combined with an anterior capsular release and an ulnar nerve decompression to recover elbow motion. This case highlights the value of advanced imaging in patients presenting with an atraumatic, painful, and progressive elbow contracture.
Coal communities and the U.S. energy transition: A policy corridors assessment

Abstract Local economies with immediate ties to coal-fired power generation face acute challenges from energy system transitions, particularly in the United States where energy policy is heavily devolved and uncoordinated. This study employs a community resilience and transition theory framework to examine how federal and state policies enable or constrain transition planning in rural, coal communities in the U.S. West. Our mixed-methods approach incorporates policy and document analysis with in-depth interviews with policy experts and practitioners. We find that the absence of a national energy transition policy exacerbates uncertainty for coal communities, and as a consequence, two distinct and diverging policy corridors emerge at the state level. According to expert interviews, existing transition assistance policies do not align with the needs and capacity of transitioning coal communities. Together, these findings highlight the need for policies that coordinate the energy transition and provide opportunities and resources that support communities navigating the social and economic impacts of transition.
Numerical solutions of the inviscid Burgers equation with the discontinuous Galerkin method

Solutions to the inviscid Burgers equation are numerically computed with the discontinuous Galerkin method with basis functions up to 16th order. Simulation results show that shock waves are effectively modeled and that in the absence of filtering, significant oscillations are observed.
Benjamin N. Cardozo: Judge, Justice, Scholar (Foreword)

On March 23-24, 2017, Touro Law Center and the Jewish Law Institute hosted a national conference: Benjamin N. Cardozo: Judge, Justice, Scholar. More than thirty judges, lawyers, and scholars, hailing from across the United States, explored topics that included: Cardozo and torts; Cardozo and contracts; Cardozo and judicial decision-making; Cardozo’s judicial style; Cardozo and the legal profession; Cardozo, law, and society; Cardozo’s jurisprudence; and Justice Cardozo. The conference proceedings also included a keynote address by Professor Andrew Kaufman, Cardozo’s biographer, and a video message from Chief Judge Janet DiFiore of the New York State Court of Appeals. The articles published in this Symposium Issue of the Touro Law Review provide a sampling of the papers presented at the conference, illustrating the variety of topics explored and the range of perspectives represented.
Chain of Values: Examining the Economic Impacts of Blockchain on the Value-Added Tax System

Blockchain technology can benefit inter-organizational activities by improving data integrity, increasing transaction transparency, and decreasing transaction costs. In this paper, we discuss the s...
Social Influence Effect on Consumers’ Intention to Adopt Mobile Banking Services

This article analyzes how the perception of risk moderates the relationships between social influence and the characteristics of personal innovativeness (PI), perceived utility (PU) and trust, lead...
Igniting Inquiry: Development and Implementation of a Novel Journal Club Curriculum in an Emergency Medicine Residency.

Abstract Background The journal club is a long-standing pillar of medical education and medical practice, although its components and format are quite variable. In addition, selecting literature for discussion must strike a delicate balance between reviewing seminal and durable articles with that of emerging evidence, all while complementing a residency curriculum. Although the critical appraisal of literature is a fundamental skill of the practicing physician, a universal curriculum has not yet been optimized to facilitate journal club. Objective We sought to design and implement a comprehensive, complementary, and evidence-based journal club curriculum that was modular in design, reproducible, and effective at generating participation. Methods Our novel curricular design incorporates many evidence-based components, including optimizing the learning environment, providing ease of access to resources, and using educational methodology that immerses learners in the experience in a structured manner. In addition, the curriculum complements, but does not duplicate, the core residency curriculum. In 2020, we analyzed our data, using descriptive and comparative statistical methods. Results We demonstrated significant improvement in common metrics used to analyze the efficacy of the journal club, including attendance and participation. Significant improvements were seen in both resident and attending participation. Conclusions Our design methods used resources easily available to our residency program and commonly available to others, with minimal time and resource cost. Further study is required to measure long-term educational outcomes.
Can I Be Who I Am? Psychological Authenticity Climate And Employee Outcomes

We propose and test the construct of psychological authenticity climate, which we define as a psychological climate where employees perceive that their organization encourages and provides a safe e...
Radiation-reprogrammed glioma stem cells generate vascular-like cells to build a trophic niche driving tumor recurrence

Abstract Treatment-refractory glioma stem and tumor cells exhibit phenotypic plasticity driving recurrence, but the underlying molecular mechanisms remain to be elucidated. Here, we employed single-cell and whole transcriptomic analyses to discover that radiation induces a dynamic shift in functional states of glioma cells allowing for acquisition of vascular endothelial-like and pericyte-like cell phenotypes. These vascular-like cells provide a trophic niche to promote proliferation of irradiated glioma cells, and their selective depletion results in reduced tumor growth post-treatment in vivo. Mechanistically, the acquisition of vascular-like phenotype is driven by increased chromatin accessibility and H3K27 acetylation in specific vascular gene regions post-treatment. Blocking P300 histone acetyltransferase activity reverses the epigenetic changes induced by radiation, and inhibits the phenotypic transition and tumor growth. Our findings highlight an important role for P300 histone acetyltransferase in treatment-induced plasticity and opens a new therapeutic avenue for preventing glioma recurrence. Significance Our study demonstrates that radiation therapy promotes glioma resistance by inducing vascular-like phenotypes in GSC that, in turn, aid in proliferation of the remaining tumor cells. This phenotype switch is mediated by P300 HAT, and inhibition of this enzyme is a potential therapeutic target for preventing glioma recurrence following radiation.
Restless Legs Syndrome

Restless legs syndrome (RLS) is a disorder that was first described by Thomas Willis in 1672. Much later, authors referred to this condition variably as “anxietas tibiarum” and “leg jitters.” On the basis of a large series of patients, Ekbom, a Swedish physician, coined the term “restless legs” in 1944 and gave the first full clinical description of RLS. Thus, RLS is sometimes referred to as “Ekbom’s syndrome.” He found that about 5% of normal subjects report occasional crawling sensations in their legs and that familial clustering occurs in some cases. He also described secondary forms due to anemia or pregnancy. Ekbom’s son later described instances of RLS after gastric surgery, presumably due to iron deficiency.
The Circumscribed Radicalism of New Deal Catholicism: Catholic Liberalism in the 1930s

This paper, a chapter in a draft book manuscript, considers American Catholic social thought in the 1930s. Particular attention is given to the manner in which the embrace of democratic liberalism both advanced yet ultimately limited the moral possibilities of Catholic political action.
An integrated testing and CAE application methodology for curtain airbag development

The Curtain Airbag (CAB) is used currently to provide head and neck protection for the front-seat and rear-seat vehicle occupants during side-impact collisions and vehicle rollovers. The coated fabric materials are used in CABs for occupant protection in side impact and rollover events. In this paper the design and development study of CABs is described by using simulation and physical tests. The mechanical properties for the airbag material are determined by uniaxial test in the fill and warp directions. Shear strength is also evaluated by using the uniaxial test, but the specimen is cut along 45° angle. These test values are used in the finite element (FE) simulations. In this paper, a methodology of the design study is discussed. A Free Motion Headform (FMH) impacting a pole with a pillow shaped airbag is used in the design study. The influences of CAB design parameters such as pressure, chamber width, impact speed and hit location are evaluated. The simulations were correlated with actual tests under various conditions such as impact speeds, hit locations and various pressures in the airbag. The simulation results were compared to the physical test by Computer Aided Engineering (CAE) model correlation grading system.
Effect of formamide additive on the chemistry of silica sol-gels: Part I: NMR of silica hydrolysis

Abstract Monolithic gels can be more easily obtained when prepared with drying control chemical additives (DCCAs). The influence of formamide DCCA on the hydrolysis and early condensation of tetramethoxysilane has been studied by 29 Si NMR. It was found that formamide decreases the hydrolysis rate by 6 × but increases the polymerization rate slightly. The rate constants for both hydrolysis and condensation reactions depend upon the concentration of formamide and solution pH.
Needs Assessment of Learning Outcome Evaluation Skills among Continuing Medical Education Providers.

In a health care environment increasingly pressured by reform efforts, the effectiveness of continuing medical education (CME) providers in designing educational methods aimed at improving physician performance and the health status of their patients, as well as in measuring the results, has been inadequate. The purpose of this study was to conduct a needs assessment of CME professionals in order to better understand these inadequacies. A 1996 survey was conducted by mail of 1600 members of the Alliance for Continuing Medical Education with a response rate of 37.5% of targeted members. There was an inverse relationship between the types of evaluation measures most frequently used (physician satisfaction with program and perceptions of enhanced professional effectiveness) and the types of evaluation measures in which professionals would like to gain new skills (physician performance and the health outcomes of their patients). Major barriers to conducting outcomes evaluations were lack of time, funding, and staffing. Barriers had been overcome by using current technology, recruiting/training staff, and securing internal or external funding. In many institutions, quality utilization review departments were also measuring educational outcomes. Few publications were reported. Identified gaps offer professional development opportunities to CME professional organizations.
Activity-Dependent β-Adrenergic Modulation of Low Frequency Stimulation Induced LTP in the Hippocampal CA1 Region

Abstract β-Adrenergic receptor activation has a central role in the enhancement of memory formation that occurs during heightened states of emotional arousal. Although β-adrenergic receptor activation may enhance memory formation by modulating long-term potentiation (LTP), a candidate synaptic mechanism involved in memory formation, the cellular basis of this modulation is not fully understood. Here, we report that, in the CA1 region of the hippocampus, β-adrenergic receptor activation selectively enables the induction of LTP during long trains of 5 Hz synaptic stimulation. Protein phosphatase inhibitors mimic the effects of β-adrenergic receptor activation on 5 Hz stimulation–induced LTP, suggesting that activation of noradrenergic systems during emotional arousal may enhance memory formation by inhibiting protein phosphatases that normally oppose the induction of LTP.
Mentoring in Early Childhood Professional Development: Evaluation of the Rhode Island Child Development Specialist Apprenticeship Program

The Quality Child Care Initiative, the federal apprenticeship program applied to the field of early care and education, has been implemented in over 40 states. This federal initiative was designed to reduce turnover, increase wages, provide a more stable environment for children, and lower the concern of parents. Rhode Island received funding in 2001 to create and implement a professional development apprenticeship program for early childhood educators known as The Rhode Island Child Development Specialist Apprenticeship Program (RICDSAP). As required in the federal call, an apprentice-mentor model served as the foundation for the RICDSAP. In this paper, we describe two studies designed to evaluate the RICDSAP. Study #1 investigated the three program goals of reduced staff turnover, increased wages, and enhanced classroom quality. Study #2 focused on apprentice-mentor relationships. Taken together, the two studies suggest that this model of professional development has benefits for several key constituent...
Review of the 2008 Annual Meeting of the Society of Urodynamics and Female Urology (SUFU) at the American Urological Association

The 2008 Meeting of the Society of Urodynamics and Female Urology at the American Urological Association is summarized with input from the presenters on key points of their respective presentations. Neurogenic bladder, often referred to as neurogenic voiding dysfunction, is an often complex condition that is occasionally encountered by urologists. An excellent overview of the pathophysiology, evaluation, and available management strategies was presented at the meeting as detailed in this article.
COMPETING FRAMES OF ENVIRONMENTAL CONTAMINATION: INFLUENCES ON GRASSROOTS COMMUNITY MOBILIZATION

This article provides an analysis of competing frames of environmental contamination in a working class neighborhood of Buffalo, New York. Through in-depth interviewing, document analysis, and participant observation, I locate and analyze emerging frames presented from local media and government sources. I argue that the most prominent frames emerged by means of local media and government, as residents referred to these most commonly as sources for their understanding of the issues facing their community. However, the information they were most likely to portray was based on resident activist and scientific reports, respectively. I argue that these frames competed in a way that challenged mobilization efforts. How do individuals work together when they may believe entirely different frameworks as explanations of the problems they seek to resolve? Framing influences which message individuals hear, which they choose to adopt, and whether they react. In this case, two prominent frames emerging from media and...
Does aspirin cause acute or chronic renal failure in experimental animals and in humans

There are conflicting reports on the ability of aspirin as a single agent to cause acute or chronic renal failure in experimental animals. Chronic administration of aspirin alone over 18 to 68 weeks in doses of 120 to 500 mg/kg/d has been reported to cause renal papillary necrosis in rats. However, some investigators have been unable to produce renal papillary necrosis in other species or in rats given lower divided doses comparable to therapeutic doses used in humans. In a variety of rat strains, aspirin administered as a single high dose intravenously or by oral gavage produces acute tubular necrosis of proximal tubules, rarely accompanied by renal papillary necrosis in susceptible strains. Several human studies have addressed the chronic nephrotoxicity of aspirin alone or relative risk of end-stage renal disease in association with aspirin use after correction for other analgesics. With the exception of one case control study demonstrating a low, but statistically significant risk of end-stage renal disease in association with aspirin use, all other case control studies and several prospective studies have been unable to identify a significant risk of chronic renal failure in patients using aspirin alone in therapeutic doses. In healthy adults, short-term aspirin administration in therapeutic doses has no effect on creatinine clearance, urine volume, osmolar clearance, or sodium and potassium excretion. However, in predisposed individuals with glomerulonephritis, cirrhosis, and chronic renal insufficiency, and in children with congestive heart failure, short-term aspirin use in therapeutic doses may precipitate reversible acute renal failure. Acute aspirin intoxication (>300 mg/kg) frequently causes acute renal failure and doses of 500 mg/kg may be lethal. Chronic salicylate intoxication has been reported to cause reversible or irreversible acute renal failure in association with a pseudosepsis syndrome.
The effects of collisional quenching on degenerate four-wave mixing

We report a theoretical and experimental investigation of the effects of collisional quenching on resonant degenerate four-wave mixing (DFWM). Using single-mode laser radiation, peak signal intensity measurements were performed on an isolated line in the A – X transition of NO. By using appropriate mixtures of N2 and CO2 as buffer gases, we varied the collisional quenching rate over several orders of magnitude while maintaining a fixed total collisional dephasing rate. The mixtures had approximately 100 Torr total pressure and were at room temperature. For I/I sat approximately equal to 0.02, DFWM intensities were found to be less affected by variations in quench rate than were laser-induced fluorescence (LIF) intensities (I and I sat are the pump laser and one-photon saturation intensities, respectively). Moreover, for I/I sat roughly equal to 0.5, DFWM intensities were observed to be nearly independent of quench rate. The results are compared to two theoretical predictions, with good agreement observed. Both theories indicate that the minimum sensitivity of DFWM to quenching occurs near I/I sat≈1.
Mechanical properties of out-of-autoclave non-crimp fabric epoxy composites for manufacturing plant elevations

Mechanical properties of a commercial out-of-autoclave non-crimp fabric epoxy prepreg (AR2527 NCF) composite were investigated in detail for the manufacturing plant elevations. To simulate the effects of elevation, the vacuum pump used for pulling vacuum from the laminate during debulking and curing was adjusted to provide two different vacuum pressures: 1) 96 kPa corresponding to 450 m elevation in Wichita KS, and 2) 84 kPa corresponding to 1550 m elevation in Denver CO. One laminate for each vacuum pressure was cured in an oven using manufacturer’s recommended cure cycle and subsequently, the laminates were machined into appropriate mechanical test coupons tested at room temperature. It was observed that the average short beam shear, combined loading compression, and flexural strength of the prepreg dropped 5%, 9%, and 12% as a result of 1100 m increase in the elevation. It was also observed that the two laminates had similar porosity (∼4%). The decrease in mechanical properties of the prepreg was attributed to the increase in resin content of the laminate.Copyright © 2014 by ASME
Non-optimal onsets in Chamicuro: an inventory maximised in coda position

The widely attested onset/coda asymmetry involves a situation in which the inventory of phonemes in syllable-final position in a particular language is a subset of those which contrast in onsets. The inverse of this pattern has been claimed to never occur (Goldsmith 1990, Beckman 1998). However, this prediction is falsified by Chamicuro, a Peruvian language in which /h/ and /[glottal plosive]/ are systematically restricted to coda position. Since no permutation of all known constraints can account for this unusual distribution, a new constraint is necessary. I propose that we invoke HAVEPLACE and subcategorise it for onsets. This positional markedness filter permits placeless (laryngeal) consonants to surface in codas, but blocks them in onsets. A beneficial side-effect of this analysis is that it preserves the onset/coda asymmetry while allowing /[glottal plosive]/ and /h/ to be the only principled exceptions to it.
Exposure to asbestiform minerals and radiographic chest abnormalities in a talc mining region of upstate New York

A radiologist in New York reported a high prevalence of pulmonary fibrosis in St. Lawrence and Jefferson counties. The New York State Department of Health responded by conducting a case history study of radiographic abnormalities found in the lung parenchyma and pleura of residents in Lawrence and Jefferson counties, where tremolitic talc has been mined for many years. During a 1-y period, all radiographs from 6 hospitals in the region were reviewed. A B-reader confirmed that 355 of 9,442 patients who were at least 40 y of age (3.8%) had a relevant abnormality; 60% of them reported occupational exposure to asbestiform minerals, and another 15% had a chest condition or injury that could have accounted for the abnormal radiograph. The results should be interpreted cautiously, but there was no evidence of widespread radiographic abnormalities resulting from ambient dust exposure. The data, however, support earlier studies that indicate that talc miners and millers experience excess parenchymal fibrosis and pleural changes. The data also suggest that individuals in the paper industry and construction trades may be at risk.
Low-cost fabrication of advanced polymeric composites by resin infusion processes

The resin infusion processes RTM, RFI, and VARTM have been identified as cost-effective fabrication techniques for the manufacture of complex-shape composite structures. Dry textile preforms are re...