cssi/SciSciGPT-SciSciNet huggingface dataset:
Flexible chiral pyrazolate-based metal–organic framework containing saddle-type CuI4(pyrazolate)4units

The syntheses and crystal structures of [CuI2(phbpz)]·MeOH (lp-CFA-9, lp = large-pore) and [CuI2(phbpz)] (np-CFA-9, np = narrow-pore; H2-phbpz = 3,3′,5,5′-tetraphenyl-1H,1′H-4,4′-bipyrazole) are described. The copper(I)-containing metal–organic framework (termed oordination ramework ugsburg University-9, lp-CFA-9) crystallizes in the trigonal crystal system, within the chiral space group P3221 (no. 154) and with the following unit cell parameters: a =18.2348(6), c = 16.3950(4) A, and V = 4721.1(2) A3. Lp-CFA-9 features a 3-D microporous framework structure of Cu4pz4 (pz = pyrazolate) SBUs with the D2d (= 2m) symmetry connected by single bonds creating one-dimensional channels expanding in the c-direction of the crystal lattice. The framework flexibility of CFA-9 has been demonstrated by single-crystal and powder X-ray analyses as well as by sorption measurements. CFA-9 exhibits weak binding of carbon monoxide on Cu(I) centers. The reactivity of CFA-9 towards oxidizing agents, such as H2O2, t-BuOOH and Br2 was also investigated. Additionally, CFA-9 shows luminescence upon exposure to UV radiation.
AAV: An Overview of Unanswered Questions

AAV has been studied for 55 years and has been developed as a vector for about 35 years. By now, there is a fairly good idea of the dimensions of what would be useful to know to employ AAV optimally as a vector, but there are still many unanswered questions within the system. As with all biological systems, each good experiment raises further questions to answer. This article provides an overview of those areas in which unknown information can be identified and of those questions that have not yet been recognized. Some of these are touched on in the six review articles in this issue of Human Gene Therapy.
Unilateral vestibular schwannoma and meningiomas in a patient with PIK3CA-related segmental overgrowth: Co-occurrence of mosaicism for 2 rare disorders.

A 28-year-old female with PIK3CA-related segmental overgrowth presented with headaches. She also had a unilateral vestibular schwannoma (VS), as well as 3 small ( A (p.Gly914Arg) mutation, confirming the diagnosis of PIK3CA-related overgrowth, but no mutations in NF2 were detected. Although VS has not previously been reported in PIK3CA-related segmental overgrowth, meningiomas have, raising the question of whether this patient's VS and meningiomas represent coincidental NF2 or phenotypic extension of her overgrowth syndrome. Genetic analysis of the VS revealed a heterozygous NF2 mutation c.784C>T (p.Arg262Ter) and loss of a portion of 22q, including NF2, SMARCB1, and LZTR1 genes. These results suggest that the patient has 2 different mosaic disorders, NF2 and PIK3CA-related overgrowth. The PIK3CA mutation was also present in the VS. Confirmation of the clinical diagnosis of mosaic NF2 in this patient has implications for monitoring and highlights the possibility of co-occurrence of mosaicism for multiple rare disorders in a single patient.
Radiographic study of the maxillary canine tooth of four mesaticephalic cats.

The radiopaque and radiolucent anatomical structures that are superimposed over the root of the maxillary canine tooth in mesaticephalic cats were identified on digital radiographs made at various angles. The vomer bone, the nasal bone, the palatine fissure, and the infraorbital foramen were not superimposed over the root of the canine tooth in the range of angles examined. Superimposition with the palatine sulcus (which is rarely visible clinically because of silhouetting of the soft tissues) only occurred at extreme horizontal (cross-sectional arc) angles. The second premolar tooth was superimposed at a cross-sectional angle of 80° and 90°. The structures of concern in the interpretation of radiographs of the maxillary canine tooth in mesaticephalic cats are the conchal crest, the line of conjunction between the vertical body of the maxilla and its palatine process, the incisivomaxillary canal (which is rarely visible on radiographic images), and the lachrymal canal. Because of their anatomical vicinity...
A lack of response of irrigated soybean (Glycine max L. Merr.) in rotation with cotton (Gossypium hirsutum L.) in the Mississippi Delta, USA

The effects of cotton (Gossypium hirsutum L.): soybean [Glycine max (L.) Merr.] rotations on the respective crops are limited. This manuscript discusses the response of irrigated soybean in crop rotation with cotton. An irrigated soybean: cotton rotation experiment was conducted from the year 2012 through 2015 near Elizabeth, MS. The crop rotation sequences were included continuous soybean (SSSS), continuous cotton (CCCC), cotton followed by soybean (SCSC), soybean followed by cotton (CSCS), soybean followed by two year of cotton (SCCS), and cotton followed by two year of soybean (CSSC). The rotations were grown under two production systems conventional and transgenetic with respect to weed control. During this study, a weed control treatment of (pendimethalin pre-emergence vs. glyphosate post-emergence) as included on the soybean plots was used. The soybean yields across rotations within a year were not significantly different. The means yields differed among years (3655.1, 3023.6, 3500.6 and 2600.3 Kg ha-1 for the year 2012, 2013, 2014 and 2015, respectively) and appear related to difference in rainfall/irrigation amounts. The results revealed that the weights of 100 seed samples averaged 13.9g in the year 2015 which differed from the previous years (16.2, 15.6, and 16.2g; 2012, 2013 and 2014, respectively). Therefore, the rotations of cotton with soybean appear to have neither a beneficial or negative effect on soybean yield.
Case Report: Hypertrophic Pachymeningitis (HP) from IgG4–RD (related disease) – A rare presentation or its most common cause? (P5.416)

Objective: Stress upon IgG4-RD as the commonest cause of “idiopathic” HP and the need for more inclusive diagnostic criteria Background: Identified in 2001 IgG4-RD is being recognised as the commonest cause of HP. Current concensus guidelines [Boston (2012)] require all 3 major criteria: [1]2 of 3 histopathologic features (lymphoplasmacytic infilterate(LPI), storiform fibrosis(SF) and obliterative phlebitis(OP)) [2] >10 IgG4+ cells/hpf and [3]IgG4+/IgG ratio of >40%. However for less studied meningeal and cutaneous disease a definite diagnosis could be made with presence of 1 of 2 minor criteria: [a] Serum IgG4 of >135mg/dl or [b]radiographic/histopathologic evidence of other organ involvement. Design/Methods: Case Report Results: A 62-year-old Caucassian man presented with 5 months of painless progressive vision loss and was found to have left optic nerve(ON) head atrophy, diffuse HP and retroperitoneal fibrosis. Serum and CSF studies were unremarkable, which prompted a meningeal biopsy that showed a diffuse LPI and >30 IgG4+ cells/hpf with a IgG4+/IgG ratio of >50%. His serum IgG4 returned elevated at 108. IgG4 RD-HP was diagnosed ( 2 major and 1 minor criteria met) and started on immunosupressive therapy. Conclusions: HP can be infectious, rheumatologic and neoplastic in etiology, but many remain “idiopathic”. 66% of these cases were identified as IgG4-RD in a recent review of idiopathic HP. They also identified IgG4-RD as the commonest overall cause of HP. Though LPI and SF were observed in all, 50% of their meningeal biopsies did not show OP. Our case did not show SF or OP, thus failed to meet a major criterion. Both SF/OP are uncommon in lacrimal and salivary gland disease; and rare in lymph node disease. We thus demonstrate the need for further study of the prevalence of SF/OP in histo-pathological specimens of IGG4-HP and propose liberalization of the current consensus criteria, with inclusion of the above described minor criteria. Disclosure: Dr. Topiwala has nothing to disclose. Dr. Hampton has nothing to disclose. Dr. Waitzman has nothing to disclose. Dr. Boland has nothing to disclose.
Multi-spectral frequency selective mid-infrared microbolometers.

Frequency selective detection of low energy photons is a scientific challenge using natural materials. A hypothetical surface which functions like a light funnel with very low thermal mass in order to enhance photon collection and suppress background thermal noise is the ideal solution to address both low temperature and frequency selective detection limitations of present detection systems. Here, we present a cavity-coupled quasi-three dimensional plasmonic crystal which induces impedance matching to the free space giving rise to extraordinary transmission through the sub-wavelength aperture array like a “light funnel” in coupling low energy incident photons resulting in frequency selective perfect (~100%) absorption of the incident radiation and zero back reflection. The peak wavelength of absorption of the incident light is almost independent of the angle of incidence and remains within 20% of its maximum (100%) up to θi≤45˚. This perfect absorption results from the incident light-driven localized edge “micro-plasma” currents on the lossy metallic surfaces. The wide-angle light funneling is validated with experimental measurements. Further, a super-lattice based electronic biasing circuit converts the absorbed narrow linewidth (Δλ/λ0< 0.075) photon energy inside the sub-wavelength thick film (< λ/100) to voltage output with high signal to noise ratio close to the theoretical limit. Such artificial plasmonic surfaces enable flexible scaling of light funneling response to any wavelength range by simple dimensional changes paving the path towards room temperature frequency selective low energy photon detection.
Utilization of a handheld telemedicine device in postoperative pediatric surgical care

Abstract Purpose The purpose of this study was to assess the utilization of a handheld telemedicine (TM) device in the postoperative care of pediatric surgical patients. Methods We performed postoperative TM evaluations using an advanced medical tablet immediately prior to seeing the patients in clinic as well as at two different time points from their home. The caregivers and physicians were surveyed about their overall satisfaction. Results Twenty-four postoperative patients who underwent a variety of general surgical operations were included. There were no changes to the TM plan of care following “in person” evaluations (n = 12) and no complications, missed diagnoses, emergency department visits, or additional clinic visits in those who only had TM postoperative evaluations (n = 12). Caregiver satisfaction ratings were 3.92 ± 0.28 out of 4 (4 = very satisfied). Ninety-two percent of caregivers responded that they would be comfortable with a TM-only postoperative evaluation in the future. The physician was able to formulate an accurate assessment and plan using the device. The average travel distance saved was 44.7 ± 45.5 miles (range = 10–150 miles). Conclusions These preliminary data suggest safe and effective care with high caregiver and physician satisfaction can be provided by utilizing TM in the postoperative care of pediatric surgical patients. Level of evidence IV.
How Does Nonverbal Reasoning Affect Sentence Recognition in Adults with Cochlear Implants and Normal-Hearing Peers?

Background Previous research has demonstrated an association of scores on a visual test of nonverbal reasoning, Raven's Progressive Matrices (RPM), with scores on open-set sentence recognition in quiet for adult cochlear implant (CI) users as well as for adults with normal hearing (NH) listening to noise-vocoded sentence materials. Moreover, in that study, CI users demonstrated poorer nonverbal reasoning when compared with NH peers. However, it remains unclear what underlying neurocognitive processes contributed to the association of nonverbal reasoning scores with sentence recognition, and to the poorer scores demonstrated by CI users. Objectives Three hypotheses were tested: (1) nonverbal reasoning abilities of adult CI users and normal-hearing (NH) age-matched peers would be predicted by performance on more basic neurocognitive measures of working memory capacity, information-processing speed, inhibitory control, and concentration; (2) nonverbal reasoning would mediate the effects of more basic neurocognitive functions on sentence recognition in both groups; and (3) group differences in more basic neurocognitive functions would explain the group differences previously demonstrated in nonverbal reasoning. Method Eighty-three participants (40 CI and 43 NH) underwent testing of sentence recognition using two sets of sentence materials: sentences produced by a single male talker (Harvard sentences) and high-variability sentences produced by multiple talkers (Perceptually Robust English Sentence Test Open-set, PRESTO). Participants also completed testing of nonverbal reasoning using a visual computerized RPM test, and additional neurocognitive assessments were collected using a visual Digit Span test and a Stroop Color-Word task. Multivariate regression analyses were performed to test our hypotheses while treating age as a covariate. Results In the CI group, information processing speed on the Stroop task predicted RPM performance, and RPM scores mediated the effects of information processing speed on sentence recognition abilities for both Harvard and PRESTO sentences. In contrast, for the NH group, Stroop inhibitory control predicted RPM performance, and a trend was seen towards RPM scores mediating the effects of inhibitory control on sentence recognition, but only for PRESTO sentences. Poorer RPM performance in CI users than NH controls could be partially attributed to slower information processing speed. Conclusions Neurocognitive functions contributed differentially to nonverbal reasoning performance in CI users as compared with NH peers, and nonverbal reasoning appeared to partially mediate the effects of these different neurocognitive functions on sentence recognition in both groups, at least for PRESTO sentences. Slower information processing speed accounted for poorer nonverbal reasoning scores in CI users. Thus, it may be that prolonged auditory deprivation contributes to cognitive decline through slower information processing.
Lipid Profiles at Birth Predict Teacher-Rated Child Emotional and Social Development 5 Years Later:

The fetal environment has been increasingly implicated in later psychological health, but the role of lipids is unknown. Drawing on the ethnically diverse Born in Bradford (BiB) birth cohort, the current study related levels of high-density lipoprotein (HDL), very-low-density lipoprotein (VLDL), and triglycerides in umbilical cord blood to 1,369 children's teacher-rated psychosocial competence approximately 5 years later. Results of ordinal logistic regressions indicated that low levels of HDL, high levels of VLDL, and high levels of triglycerides predicted greater likelihood of being rated as less competent in domains of emotion regulation, self-awareness, and interpersonal functioning. Furthermore, these results generalized across ethnic background and children's sex and were not accounted for by variables reflecting mothers' psychological or physical health, children's physical health, or children's special education status. Together, these results identify fetal exposure to anomalous lipid levels as a possible contributor to subsequent psychological health and social functioning.
Pleiotrophin: Activity and Mechanism

Pleiotrophin (PTN) is a potent mitogenic cytokine with a high affinity for the polysaccharide glycosaminoglycan (GAG). Although it is most strongly associated with neural development during embryogenesis and the neonatal period, its expression has also been linked to a plethora of other physiological events including cancer metastasis, angiogenesis, bone development, and inflammation. A considerable amount of research has been carried out to understand the mechanisms by which PTN regulates these events. In particular, PTN has now been shown to bind a diverse collection of receptors including many GAG-containing proteoglycans. These interactions lead to the activation of many intracellular kinases and, ultimately, activation and transformation of cells. Structural studies of PTN in complex with both GAG and domains from its non-proteoglycan receptors reveal a binding mechanism that relies on electrostatic interactions and points to PTN-induced receptor oligomerization as one of the possible ways PTN uses to control cellular functions.
INFRARED SPECTRA AND STRUCTURE OF POLYALDEHYDES

Abstract The infrared spectra of ten polymers of aliphatic aldehydes have been investigated. They show that the polyaldehydes are substituted polyoxymethylenes of the general formula HO —(CHR—O—)nH. The number of monomer units in the repeat unit and possible chain configurations of some of the polymers are discussed.
The Athlete Gratitude Group (TAGG): Effects of coach participation in a positive psychology intervention with youth athletes

Learning how to cultivate gratitude can be a valuable skill for life and sport, allowing one to reframe negative situations, enhance interpersonal relationships, and build resilience. While one-tim...
Investigating the Manifestations of Bias in Professional Noticing of Mathematical Thinking among Preservice Teachers.

This study examines potential bias with respect to perceived gender and ethnicity in preservice teachers’ professional noticing of children’s mathematical thinking. The goal of the study was to explore how, and to what extent bias emerges within pre-service teachers’ professional noticing of children of differing perceived races and genders. Our findings suggest that bias tends to emerge in the interpreting phase of professional noticing; however, such emergence did not appear to vary in conjunction with the perceived ethnicity and gender of the student. Further, our findings suggest that the inclusion of visual imagery (i.e. photos) influence the manifestation of bias among preservice teachers to some degree when professionally noticing in the context of a written case.
Research on DC Line Fault Recovery Sequence of Yongren-Funing HVDC Project

Basic design of DC line fault restart principle of Yongren-Funing HVDC project is firstly introduced. Then the protection configuration and response characteristics of DC fault recovery is theoretically analyzed. Subsequently, a simulation model of Yongren-Funing HVDC is built in RTDS real-time environment. Simulation of the DC line fault and corresponding fault recovery is performed. Responses of the typical electrical quantities such as voltage, current and power in the rectifier and inverter side are analyzed. In addition, field experiments results are compared with the ones gets from the simulation. This comparison study validates the effectiveness of the control and protection system. Moreover, the fault restart principle meets the design requirement. as a result, the fault restart principle and protection configuration provide in this paper is useful to the design and operation of other newly-built HVDC projects.
Evolution of Cyber-Security Research in an Industrial Setting

The software that increasingly undergirds our daily lives, national infrastructure, and defense systems continues to grow in size and complexity, incorporating far-reaching networks of open-source components and third-party dependencies. The task of analyzing and protecting these bloated and sprawling software systems is qualitatively more difficult than it was just a decade ago. We are also faced with a growing need to protect against cyber threats that continue to increase in frequency and sophistication.The primary goal of industrial research in our field is to develop and transition promising solutions to cyber-security problems into real-world settings. This process is a race against the growing complexity of the software that we seek to protect. Winning this race requires novel solutions to the challenges of scalability, precision, and the dearth of human cyber-security expertise.In recent years, we found ourselves revisiting old solutions to program representation, vulnerability detection, and reverse engineering. Such rethinking is most successful when it isolates limiting factors and addresses them by shifting into domains in which powerful new computational resources and techniques provide order-of-magnitude increases in computational and developer productivity.In this talk, I will start by reviewing some of the relevant technology trends and then give examples of reinvented solutions, enabled by new paradigms and computational resources.
A New Algorithm for Estimating Surface Roughness Using Interferometric Synthetic Aperture Radar (InSAR) Data

In this study, we developed a new SAR/InSAR-based land-cover classification algorithm for estimating surface roughness, a key parameter that is critical for accurate compound flood modeling. We successfully classified the Greater Houston area and New Orleans into nine classes with distinct surface roughness using L-band ALOS PALSAR-1 data. The ALOS-derived surface roughness estimates show an excellent agreement with those derived from NOAA's Coastal Change Analysis Program (C-CAP, 2010) land-cover classification data acquired around the same time. The new algorithm allows us to fill the temporal gaps in the existing surface roughness database. The radar-derived surface roughness estimates will be fed into the the Advanced Circulation (AD-CIRC) modeling framework to understand the compound flood risk associated with rapid land-cover changes due to urban expansion over the last decade.
Crystal structure of metronidazolium tetra-chlorido-aurate(III).

Metronidazole (MET) [systematic names: 1-(2-hy­droxy­eth­yl)-2-methyl-5-nitro-1H-imidazole and 2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethanol] is a medication that is used to treat infections from a variety of anaerobic organisms. As with other imidazole derivatives, metronidazole is also susceptible to protonation. However, there are few reports of the structures of metronidazolium derivatives. In the title compound, (C6H10N3O3)[AuCl4] [systematic name: 1-(2-hy­droxy­eth­yl)-2-methyl-5-nitro-1H-imidazol-3-ium tetra­chlorido­aur­ate(III)], the asymmetric unit consists of a metronidazolium cation, [H(MET)]+, and a tetra­chlorido­aurate(III) anion, [AuCl4]−, in which the AuIII ion is in a slightly distorted square-planar coordination environment. In the cation, the nitro group is essentially coplanar with the imidazole ring, as indicated by an O N—C=C torsion angle of −0.2 (4)°, while the hy­droxy­ethyl group is in a coiled conformation, with an O(H)—C—C—N torsion angle of 62.3 (3)°. In the crystal, the anion and cation are linked by an inter­molecular O—H⋯Cl hydrogen bond. In addition, the N—H group of the metronidazolium ion serves as a hydrogen-bond donor to the O atom of the hy­droxy­ethyl group of a symmetry-related mol­ecule, leading to the formation of chains along [010].
The GC box and TATA transcription control elements in the P38 promoter of the minute virus of mice are necessary and sufficient for transactivation by the nonstructural protein NS1.

Abstract To further define the transcriptional regulation of the P38 promoter in the minute virus of mice (MVM) genome, we constructed a series of internal deletion and linker scanning mutations. The mutant P38 constructs were assayed for transcriptional activity in vitro by primer extension analysis with nuclear extracts from murine A92L fibroblasts. Mutations which disrupted the GC box and TATA box severely reduced transcription in vitro. DNase I footprinting analysis confirmed that the murine transcription factor Sp1 bound to the GC box; however, no factors were observed interacting with a putative transcriptional activation regulatory element, termed the TAR element. The linker scanning mutations were analyzed in vivo by using a chloramphenicol acetyltransferase expression assay system, in both the presence and absence of constructs expressing the viral nonstructural protein, NS1. The ability of NS1 to transactivate the P38 promoter (up to 1,000-fold) depended entirely on the presence of intact GC and TATA box sequences. Disruption of the TAR element by either linker insertion mutations or an internal deletion did not inhibit transactivation of the P38 promoter. These results suggest that NS1 transactivates the P38 promoter indirectly by interacting with one or more components of the P38 core-transcription complex.
The Theory of Large-Scale Ocean Circulation: Reduced Equations for Large-Scale Motion

Scaling As a model of the fluid motion and thermodynamics of the Earth's oceans, the basic equations (1.15)–(1.19) include a formidable array of distinct types of physical processes, from divergence of molecular diffusive fluxes on scales of millimeters to coherent fluid flow on the scales of the Earth's circumference, a range of space scales of order 10 10 . This range of scales is comparable to that between the molecular scale and the scale of a mammal's body. Thus, in a rough sense, the problem of using these equations to understand the large-scale structure of the ocean is comparable in difficulty to using numerical computations of molecular interactions to simulate the behavior of a mammal. Numerical solution of this full set of equations is thus well beyond current computational capacities and will remain so for the foreseeable futuremore. Furthermore, these equations are sufficiently challenging that fundamental mathematical properties, such as the existence and uniqueness of solutions, are not established. Some of these basic properties remain a subject of mathematical research even for the incompressible Navier-Stokes equations, a simplified set of four equations that may be obtained from (1.15) and (1.16) by replacing the density variable ρ with a constant value ρ 0 . Despite these formidable challenges, it is possible to make progress by using a combination of mathematical and physical reasoning to derive simplified, or reduced, equation sets that describe motions on the largest space and time scales of interest.
Energy Technology R & D and the Greenhouse Effect

Global warming from rising atmospheric CO{sub 2} concentrations is linked to fossil fuel use, which, in turn, is directly linked to energy end-use needs and what technologies we employ to meet those needs. None of the nonfossil options are ready yet to displace fossil fuels on the scale necessary to stop this rise. What do heat pumps have to do with the greenhouse warming effect First, heat pumps represent one technology that can be used to increase the efficiency of energy use, which is the best near to mid-term strategy for reducing the rate of greenhouse warming. Also, chlorofluorocarbons (CFCs) used in heat pump, air conditioning, and refrigeration equipment have emerged as potential greenhouse gases.'' Future heat pump technology development therefore faces a complex set of trade-offs between direct atmospheric effects from CFC substitutes, indirect effects associated with energy efficiency and CO{sub 2} emissions, and providing options which can be used in the developing nations. Industrialized nations must recognize that solutions to these global environmental problems require international cooperation and worldwide participation. 12 refs., 7 figs., 3 tabs.
A meta-language for systems architecting

The aim of this research is to design an executable meta-language that supports system architects' modeling process by automating certain model construction, manipulation and simulation tasks. This language specifically addresses the needs in systematically communicating architects' intent with a wide range of stakeholders and to organize knowledge from various domains. Our investigation into existing architecting approaches and technologies has pointed out the need to develop a simple and intuitive, yet formal language that expresses multiple layers of abstractions, provides reflexive knowledge about the models, mechanizes data exchange and manipulation, while allow integration with legacy infrastructures. A small set of linguistic primitives, stateful objects and processes that transform them, were identified as both required and sufficient building blocks of the meta-language, specified as an Object-Process Network (OPN). To demonstrate the applicability of OPN, a software environment has been developed and applied to define meta-models of large-scale complex system architectures such as space transportation systems. OPN provides three supporting aspects of architectural modeling. As a declarative language, OPN provides a diagrammatic formal language to help architects specify the space of architectural options. As an imperative language, OPN automates the process of creating architectural option instances and computes associated performance metrics for those instances. As a simulation language, OPN uses a function-algebraic model to subsume and compose discrete, continuous, and probabilistic events within one unified execution engine. To demonstrate its practical value in large-scale engineering systems, the research applied OPN to two space exploration programs and one aircraft design problem. In our experiments, OPN was able to significantly change the modeling and architectural reasoning process by automating a number of manual model construction, manipulation, and simulation tasks. (Copies available exclusively from MIT Libraries, Rm. 14-0551, Cambridge, MA 02139-4307. Ph. 617-253-5668; Fax 617-253-1690.)
Silicon photonic crystals and photonic wires circuits

We will review the latest results on development of submicron silicon-on-insulator waveguiding structures - photonic crystals and single-mode strip waveguides (photonic wires)
Evaluation techniques for quantum mechanical integrals

The nullity of quantum-mechanical integrals can often be deduced by examining the orthogonal properties of the polynomial components in the integrand. Where the integral is nonzero, Gaussian quadratures are simple, direct and accurate, and often obviate the need for expanding the components in orthogonal polynomials [1]. On the other hand, the summation-orthogonal expansion coefficients associated with Gaussian quadratures can provide information on quadrature accuracy. The usual convergence test comparing results from two different formulas often yields false convergence signals, but can be strengthened by comparing these expansion coefficients also [2].
Selenium and Vitamin E Influence upon the in vitro Uptake of Se75 By Ovine Blood Cells.

Whole blood from ewes being fed a purified diet containing urea as the sole nitrogen source was used to determine the in vitro uptake of selenium by ovine blood cells. Selenium-75 as selenite moved into the ovine blood cell in vitro via an oxygen-dependent transport mechanism. The magnitude of this influx was inversely proportional to the dietary intake of selenium, but was not affected by dietary vitamin E. The uptake of sulfur, zinc, or cesium was not influenced by dietary selenium level. (auth)
Plasminogen activator inhibitor type 2: an intracellular keratinocyte differentiation product that is incorporated into the cornified envelope.

Human epidermal keratinocytes synthesize a complex plasminogen activator proteolytic cascade, consisting of two plasminogen activating enzymes and two inhibitors, that is thought to play a role in epidermal migration and differentiation as well as in several cutaneous diseases. Quantification of the plasminogen activator cascade proteins in keratinocytes reveals that plasminogen activator inhibitor type 2 (PAI-2) is distinct from the other components (i.e., urokinase and tissue-type plasminogen activators and inhibitor type 1) in several respects: (i) PAI-2 remains mostly cell-associated, rather than secreted; (ii) The level of cell-associated PAI-2 is at least 50-fold greater than that of the other components; (iii) PAI-2 is the only component whose level is enhanced upon elevation of the Ca2+ concentration, which is well known to induce a more differentiated phenotype in keratinocyte culture. Immunocytochemical localization experiments reveal that most keratinocytes contain PAI-2, which in a subpopulation of more differentiated cells is resistant to detergent extraction. Additional immunocytochemical localization and immunoblot experiments demonstrate that some of the PAI-2 becomes incorporated into the cornified envelope during terminal differentiation of the keratinocyte. These studies raise the possibility that PAI-2 may have an intracellular role associated with the terminal stage of keratinocyte differentiation.
The face of multiculturalism in Korea: Media ritual as framing in news coverage of Jasmine Lee:

In 2012, Jasmine Lee, a minor media celebrity of Filipino origin, became the first non-Korean appointed to national office in the Republic of Korea. To understand the media’s framing of the meanings of this unprecedented event within the cultural context of South Korean race ideology, we analyzed all news and editorial coverage by the nation’s three largest English-language media outlets: The Korea Herald, the Korea JoongAng Daily, and The Korea Times. Using Victor Turner’s social drama theory as a methodology for this critical framing analysis, we focused on the use of on-line news sources by all three outlets. Explicating the framing process surrounding Jasmine Lee allowed us to understand the hegemonic role played by Korean journalism in the reproduction of the ongoing process of multiculturalism, as well as the media’s reproduction of its own powerful role in that cultural, ideological, economic, and legal process.
Five independent loci each control monogenic resistance to gummy stem blight in melon (Cucumis melo L.)

Inheritance and segregation analysis demonstrated that five independent genes in melon confer monogenic resistance to foliar infection by the fungal pathogen Didymella bryoniae, resulting in the disease known as gummy stem blight (GSB). In this study, two new monogenic sources of GSB resistance were characterized. Resistance in Cucumis melo PI 482398 was monogenic dominant based on segregation analysis of F1, F2 and backcross populations, while resistance in C. melo PI 482399 showed monogenic recessive inheritance. Four accessions, PI 482398, PI 157082, PI 511890, and PI 140471, each previously known to carry monogenic dominant resistance to GSB, were intercrossed to determine genetic relationships among these resistance sources. Recovery of susceptible individuals in F2 populations confirmed that these accessions possess different resistance genes. Resistance loci were designated Gsb-1 (formerly Mc, monogenic dominant resistance from PI 140471), Gsb-2 (monogenic dominant resistance from PI 157082), Gsb-3 (monogenic dominant resistance from PI 511890), Gsb-4 (monogenic dominant resistance from PI 482398) and gsb-5 (monogenic recessive resistance from PI 482399).
Inhibition by nifedipine of the indirectly induced contractile response of the rat diaphragm

Abstract The effects of nifedipine (30 ug/ml) on isometric force production of in-vitro rat diaphragm were studied during direct and indirect modes of muscle activation. During direct muscle stimulation, nifedipine potentiated isometric force during twitch and unfused tetanic stimulation. Indirectly elicited responses, evoked by stimulation of the phrenic nerve, were uniformly depressed following nifedipine. Inhibition of indirect force production increased with time, while force potentiation with direct activation remained constant. We conclude that inhibitory effects of nifedipine on the phrenic nerve-diaphragm preparation are specific for nerve or neuromuscular junction.
The (d, n) reaction on 24Mg and 28Si

Abstract The reactions 24 Mg(d, n) 25 Al and 28 Si(d, n) 29 P were studied. The J -dependent effects similar to those observed in (d, p) reactions were seen. Pronounced differences in neutron distributions resulting from I p = 2 transitions to the 1.36( 3 2 + ) and 1.96( 5 2 + ) MeV states in 29 P and to the ground state ( 5 2 + ) and 0.95 MeV state ( 3 2 + ) in 25 Al were noted. These differences were observed at incident deuteron energies of 7.0, 9.0 and 10.0 MeV. Absolute differential cross sections were determined for transitions to the states at 0, 0.45, 0.95, 1.79, 2.48, 2.68 and 3.06 MeV in 25 Al. Relative cross sections were determined for the states at 0, 1.36, 1.96 and 3.43 MeV in 29 P. The data were analysed by use of DWBA calculations and spectroscopic factors obtained for most of the above transitions. The results are compared with structure in the mirror nuclei 25 Mg and 29 Si.
Intermediating knowledge exchange between universities and businesses

Abstract The forging of links between universities and businesses is viewed increasingly as an important means of stimulating knowledge development that can lead to commercial innovation. Achieving effective knowledge exchange, however, requires the midwifery of different kinds of intermediaries often working in concert. Active and many faceted intermediation for the purposes of knowledge sharing and commercialization is essential when the knowledge is tacit or uncodified. The papers in this special section describe and discuss various intermediary mechanisms that assist universities in transferring knowledge and aiding the process of innovation. No single recipe is clearly superior but examining a variety of experiences helps to highlight the strengths of specific intermediary processes and to identify some of their shortcomings.
Octagonal washer DC SQUIDs and integrated susceptometers fabricated in a planarized sub- mu m Nb-AlO/sub x/-Nb technology

The authors have designed, fabricated, and measured a number of Nb-AlO/sub x/-Nb octagonal washer DC superconducting quantum interference devices (SQUIDs) and miniature DC SQUID susceptometers having minimum feature size down to 0.5 mu m. With SQUID inductance values on the order of 100 pH, typical noise performance is better than 1 mu Phi /sub 0// square root Hz. The small minimum feature size of input coils and pickup loop structures will facilitate tight coupling to a wide variety of systems ranging from submicron particles and structures to conventional approximately mu H input circuits. A single-washer SQUID with an 80-turn 0.5- mu m-linewidth, 630-nH input coil has user-friendly V- Phi (voltage-flux) curves and a coupled energy sensitivity of 20 h at 4.2 K. Susceptometers with pickup loops ranging from 20- mu m to 0.8- mu m across have very user-friendly V- Phi curves and a resolution of order 100 mu /sub B// square root Hz at 4.2 K for devices with the smallest loops. >
STAC-A2 on intel architecture: from scalar code to heterogeneous application

STAC-A2™ is compute and memory intensive industry benchmark in the field of market risk analysis. The benchmark specifications were created by the Securities Technology Analysis Center (aka STAC®) and are based on inputs collected from the leading trading companies, universities, and high performance computing vendors. The specifications describe the models which represent realistic market risk analysis workloads.In this paper we discuss the development steps that lead to competitive performance of the STAC-A2 benchmark executed on systems consisting of Intel® Xeon® processor(s) and an Intel® Xeon Phi™ coprocessor. We show the importance of utilization of all parallel resources available on Intel architectures to achieve maximum performance. We demonstrate that the offload extension supported by Intel® Composer XE minimizes the efforts required to create accelerated applications by using only C/C++ language.With Intel's latest implementation of the STAC-A2 benchmark we were able to achieve a significant (800%) performance gain by using a heterogeneous approach running on two Intel Xeon E5-2699 v3 processors and a single Intel® Xeon Phi™ 7120A card, compared to earlier version running on only two Intel Xeon E5-2697 v2 processors. This implementation outperforms Nvidia's implementation based on an Intel Xeon processor based server with two NVIDIA* K20Xm cards.
Echocardiographic features of combined membranous subaortic stenosis and acquired calcific aortic valvulopathy.

Summary The M-mode echocardiographic features of aortic valve structure and motion in a 45-year-old male with combined congenital subaortic diaphragm and acquired deformity of the aortic valve are described. Clinical, hemodynamic, and angiographic studies suggested calcific aortic valve disease with stenosis and insufficiency, but the additional presence of a subaortic diaphragm was not appreciated. Cardiac ultrasonography demonstrated multiple, central diastolic aortic valve cusp echoes consistent with a thickened, calcified, tricuspid aortic valve. Despite calcification of the cusps, however, enough systolic cusp excursion remained to demonstrate an early systolic, rapid movement toward closure of the right coronary cusp—a finding suggestive of fixed subvalvular obstruction. Surgery confirmed a discrete subaortic diaphragm and a tricuspid, thickened, mildly calcified aortic valve with fusion of the cusp commissures at their origins and rolling back of the cusp edges. The value of echocardiography in the evaluation of the left ventricular outflow tract and aortic valve is emphasized.
Commuting pairs of linear ordinary differential operators of orders four and six

Abstract We give an elementary and explicit description of all commuting linear ordinary differential operators of orders four and six. Our analysis gives an independent derivation of the results of Krichever and Novikov in the “rank two” case.
Prostate field cancerization: deregulated expression of macrophage inhibitory cytokine 1 (MIC-1) and platelet derived growth factor A (PDGF-A) in tumor adjacent tissue

Prostate field cancerization denotes molecular alterations in histologically normal tissues adjacent to tumors. Such alterations include deregulated protein expression, as we have previously shown for the key transcription factor early growth response 1 (EGR-1) and the lipogenic enzyme fatty acid synthase (FAS). Here we add the two secreted factors macrophage inhibitory cytokine 1 (MIC-1) and platelet derived growth factor A (PDGF-A) to the growing list of protein markers of prostate field cancerization. Expression of MIC-1 and PDGF-A was measured quantitatively by immunofluorescence and comprehensively analyzed using two methods of signal capture and several groupings of data generated in human cancerous (n = 25), histologically normal adjacent (n = 22), and disease-free (n = 6) prostate tissues. A total of 208 digitized images were analyzed. MIC-1 and PDGF-A expression in tumor tissues were elevated 7.1x to 23.4x and 1.7x to 3.7x compared to disease-free tissues, respectively (p<0.0001 to p = 0.08 and p<0.01 to p = 0.23, respectively). In support of field cancerization, MIC-1 and PDGF-A expression in adjacent tissues were elevated 7.4x to 38.4x and 1.4x to 2.7x, respectively (p<0.0001 to p<0.05 and p<0.05 to p = 0.51, respectively). Also, MIC-1 and PDGF-A expression were similar in tumor and adjacent tissues (0.3x to 1.0x; p<0.001 to p = 0.98 for MIC-1; 0.9x to 2.6x; p<0.01 to p = 1.00 for PDGF-A). All analyses indicated a high level of inter- and intra-tissue heterogeneity across all types of tissues (mean coefficient of variation of 86.0%). Our data shows that MIC-1 and PDGF-A expression is elevated in both prostate tumors and structurally intact adjacent tissues when compared to disease-free specimens, defining field cancerization. These secreted factors could promote tumorigenesis in histologically normal tissues and lead to tumor multifocality. Among several clinical applications, they could also be exploited as indicators of disease in false negative biopsies, identify areas of repeat biopsy, and add molecular information to surgical margins.
Do community colleges really divert students from earning bachelor's degrees?

Abstract This paper provides new estimates of the ‘diversion effect’ argument advanced by critics of community colleges. As emphasized by Rouse (J. Business Econ. Statist. 13 (1995) 217), information on students' desired level of schooling is essential to properly measure the diversion effect of community colleges as well as their ‘democratization effect’ increasing access to higher education. Using information on desired years of schooling from early waves of the NLSY, we find that the choice between alternative postsecondary education tracks including the choice of community college students between transfer and terminal programs is highly sensitive to years of desired schooling. Diversion effect estimates are also found to depend on whether we condition on desired schooling. For individuals who express a desire to complete at least 16 years of schooling, our diversion effect estimates lie between −0.7 and −1.0 years. These estimates are clearly dominated by positive democratization effect estimates. On balance, therefore, we find for individuals desiring a bachelor's degree that community colleges increase average educational attainment by between 0.4 and 1.0 years.
Transmission Characteristics of Suspension Seats in Multi-Axis Vibration Environments

Abstract The multi-axis vibration transmission characteristics of selected suspension seats were investigated in the laboratory. Subjects were exposed to a flat acceleration spectrum and two low frequency signals extracted from multi-axis acceleration data recorded at the floor of a passenger locomotive. Triaxial accelerations were measured at the floor of the vibration table and at the interfaces between the subject and mounted seat (seat pan and seat back). The transmission ratios between the overall seat pan and seat back accelerations and floor accelerations provided an effective tool for evaluating the effects of measurement site, vibration direction, and posture among the selected seating systems. The results showed that the system transfer matrix, estimated using a multiple-input/single-output model, would be less than ideal for predicting low frequency operational seat vibration when using suspension seats. The Seat Effective Amplitude Transmissibility (SEAT), estimated for the tested locomotive seats, was used to predict the weighted seat pan accelerations and Vibration Total Values for assessing a 1-h operational exposure in accordance with ISO 2631-1: 1997. Relevance to industry Multi-axis SEAT values can be estimated for seating systems tested in the laboratory using representative operational exposures. These values can be applied to monitored vehicle floor accelerations to target potentially harmful vibration in accordance with ISO 2631-1: 1997, assuming the operational exposures have similar frequency and magnitude characteristics. The transmission at the seat back should be considered when substantial low frequency multi-axis vibration is present.
Certification by the Karl Fischer method of the water content in SRM 2890, Water Saturated 1-Octanol, and the analysis of associated interlaboratory bias in the measurement process

The calibration of Karl Fischer instruments and reagents and the compensation for instrumental bias are essential to the accurate measurement of trace levels of water in organic and inorganic chemicals. A stable, non-hygroscopic standard, Water Saturated Octanol, which is compatible with the Karl Fischer reagents, has been prepared. This material, Standard Reference Material (SRM) 2890, is homogeneous and is certified to contain 39.24 ± 0.85 mg water/mL (expanded uncertainty) of solution (47.3 ± 1.0 mg water/g solution, expanded uncertainty) at 21.5 °C. The solubility of water in 1-octanol has been shown to be nearly constant between 10 °C and 30 °C (i.e., within 1% of the value at 21.5 °C). The results of an interlaboratory comparison exercise illustrate the utility of SRM 2890 in assessing the accuracy and bias of Karl Fischer instruments and measurements.
Fragment production in noncentral collisions of intermediate-energy heavy ions

The defining characteristics of fragment emission resulting from the non-central collision of 114Cd ions with 92Mo target nuclei at E/A = 50 MeV are presented. Charge correlations and average relative velocities for mid-velocity fragment emission exhibit significant differences when compared to standard statistical decay. These differences associated with similar velocity dissipation are indicative of the influence of the entrance channel dynamics on the fragment production process.