cssi/SciSciGPT-SciSciNet huggingface dataset:
The Society of Thoracic Surgeons Congenital Heart Surgery Database: 2018 Update on Outcomes and Quality

The Society of Thoracic Surgeons Congenital Heart Surgery Database is a comprehensive registry of clinical outcomes that captures almost all pediatric cardiac surgical operations in the United States. It is the platform for all activities of The Society of Thoracic Surgeons related to the analysis of outcomes and the improvement of quality in this subspecialty. This article summarizes current aggregate national outcomes in congenital and pediatric cardiac surgery and reviews related activities in the areas of quality measurement, performance improvement, and transparency. The reported data about aggregate national outcomes are exemplified by an analysis of 10 benchmark operation groups performed from January 2013 through December 2016. This analysis documents the overall aggregate Operative Mortality (interquartile range among all participating programs) for the following procedural groups: off-bypass coarctation repair, 1.3% (0.0% to 1.4%%); ventricular septal defect repair, 0.6% (0.0% to 0.9%); tetralogy of Fallot repair, 1.1% (0.0% to 2.0%); complete atrioventricular canal repair, 2.7% (0.0% to 4.4%); arterial switch operation, 2.2% (0.0% to 2.9%); arterial switch operation and ventricular septal defect repair, 5.1% (0.0% to 8.3%); Glenn/HemiFontan, 2.1% (0.0% to 3.1%); Fontan operation, 1.1% (0.0% to 0.0%); truncus arteriosus repair, 10.1% (0.0% to 15.4%); and Norwood procedure, 15.8% (9.0% to 25.0%).
EFFECT OF TOOTH POSITION AND CBCT SETTINGS ON IMAGE ARTIFACT AND CONTRAST-TO-NOISE RATIO GENERATED BY 4 TYPES OF ROOT-END FILLING MATERIALS

Background After endodontic surgery, radiographic assessment is the method of choice to monitor bone defect healing. Cone beam computed tomography (CBCT) scans are useful to identify the cause of surgical intervention failure or to confirm healing; however, the artifacts generated by some root-end filling material might compromise this objective. Objective(s) The aim of this study was to compare the artifact and contrast-to-noise ratios generated by four root-end filling materials at multiple CBCT exposure settings and positions within the field of view (FOV). Study Design Twelve central incisors were endodontically treated, obturated, and then retrograde-filled using amalgam, Biodentine, SuperEBA (ethoxy benzoic acid), and mineral trioxide aggregate (MTA). A phantom was created; then, tooth samples were inserted and scanned in the center and periphery of a 4 × 4 mm field of view (FOV) using a Morita MCT-1 F8 (at multiple kV and degree acquisition settings). Image J was used to determine the artifact and contrast-to-noise generated at the same relative slice image of each tooth. Results Artifacts FOV position: periphery had less artifact than central (P value CNR FOV position: Periphery had higher contrast-to-noise ratio (CNR) than central (P value Discussion/Conclusions Biodentine, MTA, and SuperEBA are biomechanically adequate for retrograde obturation because they generated significantly less artifact compared with amalgam. The use of the 360° image slice acquisition mode generated significantly less artifact than the 180o setting for all materials. Finally, a periphery position led to lower artifact and higher CNR compared with the central position, a finding that was contrary to previous findings in the literature.
On Latin American Populism, And Its Echoes Around the World

In this article, I discuss the ways in which populist experiments have evolved historically. Populists are charismatic leaders who use a fiery rhetoric to pitch the interests of "the people" against those of banks, large firms, multinational companies, the International Monetary Fund, and immigrants. Populists implement redistributive policies that violate the basic laws of economics, and in particular budget constraints. Most populist experiments go through five distinct phases that span from euphoria to collapse. Historically, the vast majority of populist episodes end up badly; incomes of the poor and middle class tend to be lower than when the experiment was launched. I argue that many of the characteristics of traditional Latin American populism are present in more recent manifestations from around the globe.
Measurement of antibacterial properties of foil-backed electrospun nanofibers

Current methodologies for evaluation of antibacterial properties of traditional textiles are not applicable to foil-backed, poorly-absorbent electrospun nanofiber materials, since existing test methods require absorbent fabrics. Since electrospun nanofibers are adhered to the foil backing only by electrostatic interactions, methods used to evaluate antibacterial properties of surfaces cannot be used because these protocols cause the nanofibers to lift from the foil backing. Therefore, a novel method for measurement of the antibacterial properties of electrospun metallic foil-backed nanofiber materials was developed. This method indicated that acetate-based nanofibers manufactured to contain 5 to 30 weight percent of cold-pressed hemp seed oil or full-spectrum hemp extract inhibited the growth of Staphylococcus aureus in a dose-dependent manner, from 85.3% (SEM = 2.2) inhibition to 99.3% (SEM = 0.15) inhibition, respectively. This testing method represents an advanced manufacturing prototype procedure for assessment of antibacterial properties of novel electrospun, metallic foil-backed nanofiber materials.
El tributo a la Triple Alianza

Los tributos enviados a las capitales de la Triple Alianza contribuyeron sustancialmente a la expansion del imperio, al crecimiento y la estabilidad economica de esas capitales, y a la suntuosidad de palacios reales, eventos politicos y ceremonias religiosas. Conforme el imperio prospero, las exigencias del tributo se hicieron mas gravosas y se puso mas enfasis en los bienes suntuarios
A survey of fiber laser technology in light of laser particle accelerator

Fiber laser technology and related performance and maturity are surveyed with the perspectives of laser acceleration. Advantageous fiber attributes allow high efficiencies in energy-conversion and ...
The Inadequacy of Husserlian Formal Mereology for the Regional Ontology of Chemical Wholes

In his book, History as a Science and the System of the Sciences, Thomas Seebohm articulates the view that history can serve to mediate between the sciences of explanation and the sciences of interpretation, that is, between the natural sciences and the human sciences. Among other things, Seebohm analyzes history from a phenomenological perspective to reveal the material foundations of the historical human sciences in the lifeworld. As a preliminary to his analyses, Seebohm examines the formal and material presuppositions of phenomenological epistemology, as well as the emergence of the human sciences and the traditional distinctions and divisions that are made between the natural and the human sciences.
A MALIGNANT IMAGING COURSE OF A BENIGN MASS

Precise diagnosis requires a multimodality imaging approach, which can dramatically change treatment course. 75-year-old female with history of bypass grafts to the left coronary system and residual intermediate stenosis of right coronary artery (RCA) was evaluated for stable angina with stress
1001-P: Do-It-Yourself (DIY) Loop Is Associated with Psychosocial Benefits

Loop is a DIY app for automated insulin delivery using an iPhone and commercial continuous glucose monitor (CGM) and insulin pump. An ongoing observational study evaluates glycemic control, adverse event rates, and patient-reported outcomes (PROs) among adults with type 1 diabetes (T1D). This abstract presents PROs data for the first 3 months using Loop. Participants were recruited through online postings and packaging of the Loop RileyLink. Device data were collected via the Tidepool Mobile App, including available CGM data at enrollment. PROs evaluated diabetes distress, technology attitudes and problem solving, hypoglycemia fears and confidence, and sleep quality with validated surveys. There were 290 new users who started Loop within the past 7 days. Complete data were available for 254; 5 stopped using Loop and 31 did not complete PROs at 3 months. Demographic and clinical characteristics are in the Table. t tests and effect sizes showed statistically (p This is the first study to systematically measure PROs in people using a DIY system, with new users voicing high satisfaction and across the board positive PRO scores. Disclosure K.K. Hood: Research Support; Self; Dexcom, Inc. Speaker’s Bureau; Self; LifeScan, Inc., MedIQ. J.J. Wong: None. S. Hanes: None. R. Bailey: None. P. Calhoun: Stock/Shareholder; Self; Dexcom, Inc. R. Beck: None. V.R. Barnes-Lomen: None. J.W. Lum: None. B. Arbiter: Employee; Self; Tidepool. Stock/Shareholder; Self; Abbott Laboratories, Dexcom, Inc., Tandem Diabetes Care. D. Naranjo: None. Funding The Leona M. and Harry B. Helmsley Charitable Trust
Fecundity is impaired in a mouse model of osteogenesis imperfecta

Osteogenesis imperfecta (OI), or brittle bone disease, is most often caused by mutations in genes encoding type I collagen or proteins that process it. Women with OI have a small, but significant increase in risk of serious pregnancy complications including uterine rupture. Here, the OI mouse, Col1a2oim/oim , was used to examine the effects of collagen mutation on establishment and maintenance of pregnancy. Picrosirius birefringence was faint in Col1a2oim/oim uteri, indicating diminished collagen in the myometrium and endometrium. There was some evidence of increased uterine gland number (p = .055) and size (p = .12) in (p = .055) virgin uteri, though the they were not significantly different than controls. There were no differences in the number of corpora lutea, or the time from pairing to delivery of pups between Col1a2oim/oim and control dams, suggesting that ovulation and conception occur normally. However, when examined at Gestation Day 6.5 (postimplantation), gestation Day 10.5 (midpregnancy), and Postnatal Days 1-2, Col1a2oim/oim dams had significantly fewer viable pups than controls overall. In pairwise comparisons, the loss was only significant in the postnatal group, suggesting the gradual loss of pups over time. Overall, the Col1a2oim/oim mouse data suggest that OI impairs uterine function in pregnancy in a way that affects a small but significant number of fetuses.
Exploring the association between compliance with measures to prevent the spread of COVID-19 and big five traits with Bayesian generalized linear model

Research has examined the association between people's compliance with measures to prevent the spread of COVID-19 and personality traits. However, previous studies were conducted with relatively small-size datasets and employed frequentist analysis that does not allow data-driven model exploration. To address the limitations, a large-scale international dataset, COVIDiSTRESS Global Survey dataset, was explored with Bayesian generalized linear model that enables identification of the best regression model. The best regression models predicting participants' compliance with Big Five traits were explored. The findings demonstrated first, all Big Five traits, except extroversion, were positively associated with compliance with general measures and distancing. Second, neuroticism, extroversion, and agreeableness were positively associated with the perceived cost of complying with the measures while conscientiousness showed negative association. The findings and the implications of the present study were discussed.
Association of operative approach with outcomes in neonates with esophageal atresia and tracheoesophageal fistula.

Abstract Purpose: We sought to evaluate the impact of thoracoscopic repair on perioperative outcomes in infants with esophageal atresia and tracheoesophageal fistula (EA/TEF). Methods: The American College of Surgeons National Surgical Quality Improvement Program pediatric database from 2014 to 2018 was queried for all neonates who underwent operative repair of EA/TEF. Operative approach based on intention to treat was correlated with perioperative outcomes, including 30-day postoperative adverse events, in logistic regression models. Results: Among 855 neonates, initial thoracoscopic repair was performed in 133 (15.6%) cases. Seventy (53%) of these cases were converted to open. Those who underwent thoracoscopic repair were more likely to be full-term (p = 0.03) when compared to those in the open repair group. There were no significant differences in perioperative outcome measures based on surgical approach except for operative time (thoracoscopic: 217 min vs. open: 180 min, p Conclusions: Thoracoscopic neonatal repair of EA/TEF continues to be used sparingly, is associated with high conversion rates, and has similar perioperative outcomes when compared to open repair. Level of evidence: III
Decline in prenatal buprenorphine/naloxone fills during the COVID-19 pandemic in the United States

Background and Aims: Pregnancy provides a critical opportunity to engage women with substance use disorder in care. Buprenorphine/naloxone treatment is associated with improved pregnancy and fetal outcomes, but prior to the COVID-19 pandemic, there were multiple barriers to accessing buprenorphine/naloxone during pregnancy. Care disruptions during the pandemic may have further exacerbated these already existing barriers. To quantify these changes, we examined trends in the number of individuals filling prescriptions for prenatal buprenorphine/naloxone prescriptions during the COVID-19 pandemic. Methods: We estimated an interrupted time series model using linked national pharmacy claims and medical claims data from May 2019 to December 2020. We estimated changes in the level and trend in the monthly number of individuals filling prescriptions for prenatal buprenorphine/naloxone during the COVID-19 pandemic. We then stratified our analyses by payer. Results: We identified 2,947 pregnant patients filling buprenorphine/naloxone prescriptions. Before the pandemic, there was positive growth in the monthly number of individuals filling prescriptions for prenatal buprenorphine/naloxone (4.83% (95% confidence interval (CI): 3.40% to 6.26%). During the pandemic, the monthly growth rate in individuals filling prescriptions for prenatal buprenorphine/naloxone declined for both patients on commercial insurance and patients on Medicaid (all payers: -5.53% (95% CI: -7.28% to -3.78%); Medicaid: -7.66% (95% CI: -10.42% to -4.90%); Commercial: -3.59% (95% CI: -5.53% to -1.66%)). Conclusion: The number of pregnant individuals filling buprenorphine/naloxone prescriptions was increasing prior to the pandemic, but this growth has been lost during the pandemic.
Time-course of recovery of peak oxygen uptake after exercise-induced muscle damage

VO2 peak has been shown to be reduced 48 h following exercise-induced muscle damage (EIMD), but it is unclear how long this reduction may persist. In this study eight endurance trained participants (21.5 ± 1.1 years old) performed a maximal exercise tests over 10-days followings EIMD. Cardiorespiratory variables were collected via open-circuit spirometry and soreness, maximal strength (MVC), motor-unit recruitment, and contractile properties were assessed prior to each test. MVC was reduced for up to 4-days (p ≤ 0.05) and soreness was evident for 10-days in the quadriceps (p 0.05). EIMD resulted in small, but prolonged reductions in VO2peak. Our findings suggest mechanisms aside from force loss and soreness are primarily responsible for the reductions in VO2peak after EIMD.
Further results on blind equalization and estimation of SIMO time-varying channels

Blind estimation of SIMO (single-input multiple-output) rapidly time-varying communications channels is considered using only the second-order statistics of the data. The time-varying channel is assumed to be described by a complex exponential basis expansion model (CE-BEM). Recently we extended the linear prediction error (including multistep linear prediction) method for blind estimation of time-invariant channels to time-varying channels represented by a CE-BEM where all active frequencies in CE-BEM were assumed to be known a priori. In this paper we present an approach where we only need to know the set of all possible frequencies in the CE-BEM, and precise knowledge of the active frequencies is not needed. A simulation example is presented to illustrate the proposed approach.
Differential effect of aminopterin on the action of estradiol and progesterone in monkeys.

Abstract The influence of Aminopterin (4-amino pteroylglutamic acid) on the action of estradiol and progesterone on the reproductive tract was tested in twelve sexually mature Rhesus monkeys. The animals were castrated and given 10 μg estradiol daily for twenty days after which each received Aminopterin daily beginning with doses of 100 μg and increased after each succeeding ten days to 200 μg, 500 μg, and 1 mg., depending upon the symptoms of vitamin deficiency. During the Aminopterin treatment, six animals were given 10 μg estradiol daily, three received 10 μg estradiol and 1.5 or 2 mg. progesterone, and three 1.5 or 2 mg. progesterone. Three of the six animals on estrogen menstruated during treatment while bleeding did not occur in those receiving progesterone. The endometria of animals given progesterone showed full progestational development. Aminopterin inhibited the action of estrogen on the vagina, had no detectable influence on the response of the cervix to estrogen, and did not modify the response of these structures to progesterone. Therefore, under these conditions, Aminopterin showed a differential action on the effects of estrogen and progesterone on the female reproductive tracts of monkeys.
Bone morphogenetic protein 7 regulates reactive gliosis in retinal astrocytes and Müller glia

Purpose The focus of this study was to determine whether bone morphogenetic proteins (BMPs) trigger reactive gliosis in retinal astrocytes and/or Muller glial cells.
Absence of endo-beta-N-acetylglucosaminidase activity in the kidneys of sheep, cattle and pig.

The kidneys of man, sheep, cattle and pig were all found to contain 1-aspartamido-beta-acetylglucosamine amidohydrolase activity. However, among these, only human kidney was found to contain endo-beta-N-acetylglucosaminidase activity. The absence of this enzyme in the kidneys of sheep and cattle explains why the oligosaccharides accumulated in, and excreted by, sheep and cattle afflicted with disorders of glycoprotein catabolism (i.e. alpha-mannosidosis and beta-mannosidosis) contain two N-acetylglucosamine residues at the reducing terminus instead of one, as is the case for human patients afflicted with similar disorders.
Evidence for the association of RNA with the ciliary basal bodies of Tetrahymena.

SUMMARY A new procedure for isolating pellicles from TetraJiymena yields stable whole pellicles in good yield. Electron microscopy of fixed pellicles showed inner membranes and basal bodies but no mitochondria. Sucrose gradient sedimentation of pellicle extracts labelled with [ s H]uridine showed an increase in the ratio 17 s RNA to 25 s RNA and little 4 s RNA. The method of long term labelling presumably excluded messenger RNA. The technique of RNA/DNA hybridization in the presence of competing RNA showed that 35 % of the pellicle RNA which could hybridize (Cot 2-3) to DNA did not contain sequences in common with ribosomal RNA. It is proposed that a stable RNA which is not mitochondrial RNA, transfer RNA or ribosomal RNA is associated with the pellicle. Fixed pellicles stained with acridine orange showed brilliant yellow-green fluorescence at the basal bodies. RNase reduced or abolished fluorescence; DNase, histone, and lysozyme had no effect. Mercaptoethanol changed the colour of the fluorescence of basal bodies from yellow-green to orange, while not changing yellow nuclear fluorescence. Fluorescence of basal bodies was seen in pellicles isolated from log-phase cells and also in synchronized cells. It is proposed that basal bodies contain, or are associated with, singlestranded RNA held in a rigid configuration by protein. The implications of this proposal are discussed.
One framework, two systems: flexible abductive methods in the problem-space paradigm applied to antibody identification and biopsy interpretation

Abstract Our goal is to build flexible knowledge-based systems which can use a variety of problem-solving methods and additional task knowledge, without altering the method or task representation. For this purpose, we use a problem-space architecture which allows opportunistic adaptation of problem-solving methods based on the particular goal, situation and knowledge available. Within this framework, we have developed an opportunistic problem-solving method for flexible abductive problem solving. The basic method was specified in terms of potential subgoals and preferences regarding the order of subgoals. This technique avoids specification of any unnecessary procedural commitments, making the resulting method very general and robust. We then developed two systems using this basic abductive method with additional domain-dependent search-control and task knowledge. The additional knowledge alters/overrides some of the minimal knowledge provided by the basic method. Behavior of these systems can change quite dramatically depending on the added increments of knowledge. Knowledge available at runtime shapes the method and hence the behavior. Moreover, even in the absence of strong domain knowledge, due to the wide coverage of the basic abductive method and the general architecture it is based on, the systems are always able to perform some problem solving — they are not brittle. The specific systems implemented are RedSoar and LiverSoar in the domain of red blood cell antibody identification and liver biopsy interpretation, respectively. We discuss the designs, implementations and evaluations of these systems, emphasizing the role the flexible abductive problem-solving method plays.
Prospects for improving economically significant Lactobacillus strains by ‘genetic technology’

Abstract Members of the genus Lactobacillus are used in a number of economically significant food and industrial fermentations. New developments in molecular cloning and genetic exchange systems may lead to improved starter cultures that have new and unusual properties.
Learning-Based Preference Modeling in Engineering Design Decision-Making

Focusing on the efforts towards a consistent preference representation in decision based engineering design, this paper presents a learning-based comparison and preference modeling process. Through effective integration of a deductive reasoning-based on designer's outcome ranking in a lottery questions-based elicitation process, this work offers a reliable framework for formulating utility functions that reflect designer's priorities accurately and consistently. It is expected that this integrated approach will reduce designer's cognitive burden, and lead to accurate and consistent preference representation. Salient features of this approach include a linear programming based dynamic preference learning method and a logical analysis of preference inconsistencies. The development of this method and its utilization in engineering design are presented in the context of a mechanism design problem and the results are discussed.
RADIATION-ANNEAL HARDENING IN NIOBIUM: AN EFFECT OF POST-IRRADIATION ANNEALING ON THE YIELD STRESS.

The effect of low-temperature annealing on the yield stress of niobium following neutron irradiation was studied. The initial increase in yield stress upon irradiation was sensitive to the interstitial carbon content. A further increase in the yield stress (“radiation-anneal hardening”) was observed after two-hour anneals near 150 and 300 °C. When the annealing temperature was raised above 400 °C, the yield stress gradually recovered toward the preirradiation value. Changes in the density and size of the radiation-produced defect clusters were determined by transmission electron microscopy following post-irradiation anneals. An analysis of the observed hardening based on a dispersed barrier model and the density and size of defect clusters indicated that post-irradiation annealing strengthened the clusters as barriers to dislocation motion by as much as a factor of two. Previous resistivity and internal friction measuremements have shown that interstitial oxygen and carbon in irradiated niobium migrate to the defect clusters at the temperatures near 150 and 300 °C, respectively. Thus, the radiation-anneal-hardening peaks at these temperatures are attributed to the trapping of oxygen and carbon, respectively, at defect clusters. There is a reduced tendency for dislocation channeling (i.e., defect cluster removal by slip dislocations) in radiation-anneal-hardened niobium, suggesting that indeed the clusters have been strengthened.
SCOUR AND DEPOSITION IN LOWER GRANITE RESERVOIR, SNAKE AND CLEARWATER RIVERS NEAR LEWISTON, IDAHO, U.S.A.

Calculation of the final levee grades for Lower Granite Reservoir at Lewiston, Idaho, required adjustment to the streambed to account for sediment deposits during the 50-year life of the project. Since the backwater reach of the reservoir behaves like a sediment trap during low flow and re-entrains material during high flow, both deposition and scour influence the final bed profile with the coarser material playing a dominant role. The simulation technique used to distribute sediment deposits (computer program known as “Scour and Deposition in Rivers and Reservoirs”) required data on inflowing sediment load, gradation of the load, gradation of material on the streambed, water-discharge hydrographs, and operating policies for the reservoir. Sediment data were lacking, so a collection program was initiated to satisfy two objectives: (1) to provide sediment-inflow data for the study, and (2) to calibrate the simulation technique. The field data, including bedload-transport rates, provide one of the most comp...
A Qualitative Study of the Long Term Impact of Welfare Reform on Cambodian American Families

Many Cambodian American families have struggled on the economic margins since their arrival to the U.S. in the 1980s. To raise families in poverty Cambodians created family survival strategies to buffer themselves against economic uncertainty and the vagaries of the social welfare system. They combine public assistance with formal and informal work activities of family members, including teenagers and young adults, to survive. With the passage of the Personal Responsibility and Work Opportunity Act of 1996 or Welfare Reform, Cambodians lost vital economic resources. Based upon a longitudinal qualitative study from 1998-2007, this article looks back on how first generation Cambodians adjusted to changes in welfare policy practices and how the loss of vital resources impacted the youth (15-19 years old) coming of age in these families. The research findings and family case histories presented in this article illustrate the shared struggle of Cambodian family members in poverty. It reveals the significant challenges second generation Cambodian Americans face to achieve higher education goals when welfare policies systematically undercut family survival strategies.
Laser-Induced Damage Mechanisms of Kevlar 49-Epoxy Composites

Influence du taux de contrainte de la temperature, des impuretes des fibres, de la matiere chimique des produits de degradation et de la teneur en humiditie
The effects of motoric action and organization on children's memory

Abstract Two experiments are reported which examine the effects of motoric activities on children's memory performance. In the first experiment, preschool, first-grade, and third-grade children were required to remember a series of color-shape pairs. The pairs were either presented as unitary configurations (i.e., colored shapes) or as non-unitary configurations (i.e., color and shape presented separately on the stimulus card). Half of the children at each grade level drew the color-shape pairs, while the remaining half simply looked at the stimulus cards. The findings revealed that the different organizations affected memory performance; however, drawing the configurations enhanced the effect of the unitary organization. The second experiment examined the effects of changing the activity during encoding from drawing to that of reconstructing replicas of the stimuli. The findings revealed that this different activity enhanced the children's memory for both unitary and non-unitary stimuli. These findings suggest that processing organizational information in memory is mediated by the specific aspects of motoric action.
A spatial analysis of FedEx and UPS: hubs, spokes, and network structure

Abstract Despite their importance to the US economy and their rapidly increasing internationalization, relatively little has been published on the geography of Federal Express and United Parcel Service. This article assesses the evolution of the two firms’ airline networks. Their hubs in the US and abroad are analyzed with attention given to location factors such as market centrality and intermediacy, supporting ground transportation networks, and competing and complementary airline networks. Their overall networks are compared with each other and with the networks of American Airlines and Southwest Airlines using several graph theory measures. FedEx and UPS are found to operate networks with a very high concentration of activity at their principal hubs (Memphis and Louisville, respectively), despite the proliferation of hubs and spokes in recent years. Finally, the future outlook for the two package express firms is examined. Key influences on their future spatial elaboration include aircraft technology and the uneven landscape of airline industry liberalization.
Three-body correlations in the ground-state decay of 26 O

Background: Theoretical calculations have shown that the energy and angular correlations in the three-body decay of the two-neutron unbound $^{26}\mathrm{O}$ can provide information on the ground-state wave function, which has been predicted to have a dineutron configuration and $2n$ halo structure.Purpose: To use the experimentally measured three-body correlations to gain insight into the properties of $^{26}\mathrm{O}$, including the decay mechanism and ground-state resonance energy.Method: $^{26}\mathrm{O}$ was produced in a one-proton knockout reaction from $^{27}\mathrm{F}$ and the $^{24}\mathrm{O}\phantom{\rule{4pt}{0ex}}+n+n$ decay products were measured using the MoNA-Sweeper setup. The three-body correlations from the $^{26}\mathrm{O}$ ground-state resonance decay were extracted. The experimental results were compared to Monte Carlo simulations in which the resonance energy and decay mechanism were varied.Results: The measured three-body correlations were well reproduced by the Monte Carlo simulations but were not sensitive to the decay mechanism due to the experimental resolutions. However, the three-body correlations were found to be sensitive to the resonance energy of $^{26}\mathrm{O}$. A $1\ensuremath{\sigma}$ upper limit of 53 keV was extracted for the ground-state resonance energy of $^{26}\mathrm{O}$.Conclusions: Future attempts to measure the three-body correlations from the ground-state decay of $^{26}\mathrm{O}$ will be very challenging due to the need for a precise measurement of the $^{24}\mathrm{O}$ momentum at the reaction point in the target.
The Thermodynamics of Liquid Helium on the Basis of the Two-Fluid Theory

The thermodynamics of liquid helium is developed in the light of the two-fluid theory, which says that below the $\ensuremath{\lambda}$-point liquid helium consists of two "phases," one a superfluid phase and one a phase of normal fluid; and the thermodynamic consequences of assuming these phases to be in equilibrium with each other are worked out. It is pointed out that there is some evidence that these phases are separated not only in momentum space, as in London's theory based on the Bose-Einstein gas, but also in ordinary space. The specific heat just above the $\ensuremath{\lambda}$-point is considered on the assumption that in this region superfluid is beginning to appear in the form of small globules; it is estimated that these globules contain around 60 to 80 helium atoms. The thermodynamic properties below the $\ensuremath{\lambda}$-point are used to estimate the entropy of mixing of the two fluids in this region. The results suggest that in this region the superfluid forms a "partially condensed system," having possibly a fibroid structure. The nature of the second-order transition at the $\ensuremath{\lambda}$-point is considered in the light of this picture. A new relation is derived for the change of the $\ensuremath{\lambda}$-point with pressure, and the change with concentration of ${\mathrm{He}}^{3}$ is also considered. The thermodynamic results, though discussed in the light of the hypothesis that the two phases separate in ordinary space as well as momentum space, depend for the most part only on pure thermodynamics and the mere existence of two phases.
Targeted quantitative proteomics for the analysis of 14 UGT1As and -2Bs in human liver using NanoUPLC-MS/MS with selected reaction monitoring

Targeted quantitative proteomics using heavy isotope dilution techniques is increasingly being utilized to quantify proteins, including UGT enzymes, in biological matrices. Here we present a multiplexed method using nanoLC-MS/MS and multiple reaction monitoring (MRM) to quantify 14 UGT1As and UGT2Bs in liver matrices. Where feasible, we employ two or more proteotypic peptides per protein, with only four proteins quantified with only one proteotypic peptide. We apply the method to analysis of a library of 60 human liver microsome (HLM) and matching S9 samples. Ten of the UGT isoforms could be detected in liver, and the expression of each was consistent with mRNA expression reported in the literature. UGT2B17 was unusual in that ∼30% of liver microsomes had no or little (<0.5 pmol/mg protein) content, consistent with a known common polymorphism. Liver S9 UGT concentrations were approximately 10-15% those of microsomes. The method was robust, precise, and reproducible and provides novel UGT expression data in human liver that will benefit rational approaches to evaluate metabolism in drug development.
Investigating the Thrust Production of a Myliobatoid-Inspired Oscillating Wing

Myliobatidae is a family of large pelagic rays including cownose, eagle and manta rays. They are extremely efficient swimmers, can cruise at high speeds and can perform turn-on-a-dime maneuvering, making these fishes excellent inspiration for an autonomous underwater vehicle. Myliobatoids have been studied extensively from a biological perspective; however the fluid mechanisms that produce thrust for their large-amplitude oscillatory-style pectoral fin flapping are unknown. An experimental robotic flapping wing has been developed that closely matches the camber and planform shapes of myliobatoids. The wing can produce significant spanwise curvature, phase delays down the span, and oscillating frequencies of up to 1 Hz, capturing the dominant kinematic modes of flapping for myliobatoids. This paper uses dye flow visualization to qualitatively characterize the fluid mechanisms at work during steady-state oscillation. It is shown that oscillatory swimming uses fundamentally different fluid mechanisms than undulatory swimming by the generation of leading-edge vortices. Lessons are distilled from studying the fluid dynamics of myliobatoids that can be applied to the design of biomimetic underwater vehicles using morphing wing technology.
On one-sided densities of arcs of positive two-dimensional measure

1. Let AB be a plane simple arc, which, considered as a point-set, has a positive two-dimensional measure. If x be a point of AB , a point x′ ≠ x is said to be to the left or to the right from x according as it belongs to the arc Ax or xB . The upper and the lower limits of the ratio [ m 2 { Ax C ( x, r )}]/π r 2 , where C ( x, r ) denotes the closed disc with centre x and radius r , as r → 0 define the upper and the lower left densities at the point x . When the two densities are equal their common value defines the left density . The right densities are defined similarly.
The impact of workplace attire on employee self‐perceptions

This study examined employee preferences for different styles of workplace attire and how wearing various styles of clothing affected their self-perceptions. Respondents felt most authoritative, trustworthy, and competent when wearing formal business attire but friendliest when wearing casual or business casual attire. Significant two-way interactions were found between dress preference and mode of dress worn on self-perceptions of productivity, trustworthiness, creativity, and friendliness. Suggestions for future research and implications for HRD professionals are proposed.
Analysis of methodology for measurement of intramyocardial pressure

We critically evaluated the major techniques for measurement of intramyocardial pressure (IMP (closed, perfusion, open, microtransducer). Each technique demonstrates a gradient in systolic IMP increasing with depth from the epicardium. The estimated magnitude of this gradient varies with the technique employed. Indirect methods (closed, perfusion) estimate a higher value for the systolic IMP gradient. The open and microtransducer methods, which measure a direct hydrostatic pressure within the myocardium, are less invasive and reflect more reliably the magnitude of IMP. The results for the open and microtransducer methods were comparable and indicate that normalized systolic IMP increases linearly from the epicardium. In the inner half of the myocardium systolic IMP approaches the level of systolic LVP and in the subendocardial layer it exceeds the systolic LVP by about 8%. A reverse IMP gradient occurred in late diastole ranging from 5 mm Hg in the subendocardial region K 25 mm Hg in the subepicardium.
Elderly Homeless: A Comparison of Older and Younger Adult Emergency Shelter Seekers in Bakersfield, California

This research report compares characteristics of older homeless adults (age 55 and older) with younger homeless and examines gender differences within each age group. Data are drawn from intake int...
Cluster of clusters (C2) model for electron counting of supracluster based on smaller cluster units

Abstract High nuclearity metal clusters are often based on vertex-, edge-, or face-sharing of small cluster units. Understanding of the bonding in these clusters in general, and their ligand requirements in particular, is a prerequisite to the design of even larger clusters. We describe here a new ‘cluster of clusters’ (C2) model which is a simple but useful approach to electron counting of high nuclearity clusters based on smaller clusters as building blocks. Specifically, the C2 model provides a simple means to calculate the number of skeletal as well as topological electron pairs of a supracluster based on its constituents (building blocks).
Survival and habitat use in translocated and resident greater prairie-chickens

Abstract Translocation, or the purposeful movement of organisms from one location to another for conservation, is currently being used to bolster populations of the endangered greater prairie-chicken (Tympanuchus cupido). We used radiotelemetry to compare survival between 58 resident birds and 54 newly translocated greater prairie-chickens that were sourced from a location more than 325 km away. Model averaged survival estimates were lower in translocated birds (0.42; 95% CI: 0.17–0.66) than in resident prairie-chickens (0.65; 95% CI: 0.46–0.79) through the breeding season. Habitat, sex and year were each included in at least 1 of the top 4 models, but the model averaged confidence intervals for each parameter encompassed zero. Survival of both resident and translocated prairie-chickens increased throughout the breeding season. Both translocated and resident prairie-chickens selected for core prairie habitat over agriculture, and birds tended to avoid surrounding private grasslands and wooded areas. We suggest that future translocation projects account for reduced survival of translocated birds when determining the appropriate release cohort sizes and sex ratios. We also recommend that future management for greater prairie-chicken habitat focus on the expansion of core protected patches of prairie to promote elevated survival and better chances of conservation success.
Basement Membrane Zone Type XV Collagen Is a Disulfide-bonded Chondroitin Sulfate Proteoglycan in Human Tissues and Cultured Cells

Type XV collagen has a widespread distribution in human tissues, but a nearly restricted localization in basement membrane zones. The alpha1(XV) chain contains a highly interrupted collagenous region of 577 residues, and noncollagenous amino- and carboxyl-terminal domains of 530 and 256 residues, respectively. Cysteines are present in each domain and consensus sequences for O-linked glycosaminoglycans are situated in the amino terminus and in two large, noncollagenous interruptions. We now report that type XV collagen is a chondroitin sulfate proteoglycan in human tissues and cultured cells, and that the alpha chains are covalently linked by interchain disulfide bonds only between the two cysteines in the collagenous region. Western blotting of tissue extracts revealed a diffuse smear with a mean size >/=400 kDa, which after chondroitinase digestion resolved into a 250-kDa band in umbilical cord, and 250- and 225-kDa bands in placenta, lung, colon, and skeletal muscle. The latter two bands were also directly visualized by alcian blue/silver staining of a purified placenta extract. In a human rhabdomyosarcoma cell line, almost all of the newly synthesized type XV collagen was secreted into the medium and upon chondroitinase digestion just the 250-kDa alpha chain was generated. Chondroitinase plus collagenase digestion of tissue and medium proteins followed by Western blotting using domain-specific antibodies revealed a 135-kDa amino-terminal fragment containing glycosaminoglycan chains and a 27-kDa fragment representing the intact carboxyl terminus. However, a truncated carboxyl peptide of approximately 8-kDa was also evident in tissue extracts containing the 225-kDa form. Our data suggest that the 225-kDa form arises from differential carboxyl cleavage of the 250-kDa form, and could explain the approximately 19-kDa endostatin-related fragments (John, H., Preissner, K. T., Forssmann, W.-G., and Standker, L. (1999) Biochemistry 38, 10217-10224), which may be liberated from the alpha1(XV) chain.
Defective lactose utilization by a mutant of Escherichia coli energy-uncoupled for lactose transport. The advantages of active transport versus facilitated diffusion.

Abstract 1. 1. The lactose operon of an Escherichia coli mutant (X71-54), energy-uncoupled for lactose transport, was transduced into an inducible β-galactosidase negative recipient. A transductant was isolated which was inducible (i + ) and possessed both β-galactosidase (z + ) and the uncoupled transport property (y UN ). 2. 2. This inducible energy-uncoupled transductant (54-41) and the constitutive mutant from which it was derived (X71-54) were defective in energy-dependent accumulation of thiogalactosides, but showed no loss of carrier-mediated transport, as compared to their respective parents. 3. 3. A striking feature of the inducible mutant 54-41 was its inability to grow on lactose in minimal medium. The addition of the gratuitous inducer thioisopropyl-β- d -galactopyranoside permitted normal growth of these cells on lactose. 4. 4. In the energy-uncoupled transductant the rate of induction of β-galactosidase by lactose and by low concentrations of thioisopropyl-β- d -galactopyranoside was much slower than that of the parental cell. 5. 6. The data are consistent with the hypothesis that for normal growth of inducible cells of lactose or melibiose, carrier-mediated entry (facilitated diffusion) of substrates is inadequate; the membrane carriers must also be capable of accumulating the sugars.
Controlled Synthesis and Assembly of Nanostructured ZnO Architectures by a Solvothermal Soft Chemistry Process

Controlled synthesis and organization of nanostructured materials using simple and low-cost methods is important in order to exploit their unique properties for practical applications. We describe the results of a systematic study of the solvothermal soft chemical synthesis of novel nanostructured ZnO architectures. Various ZnO nanostructured microspheres and microrod aggregates have been synthesized using Zn(CH3COO)2·2H2O in ethylenediamine in the presence of HAuCl4·4H2O. In the absence of HAuCl4·4H2O, fibrous and coral-like ZnO rod aggregates are obtained. The morphologies and structures of the obtained ZnO architectures can be tuned by manipulating the relative amounts and the addition sequence of Zn(CH3COO)2·2H2O and HAuCl4·4H2O. The Au(ethylenediamine)23+ complex, formed from Au3+ by combining with two ethylenediamine molecules, plays a key structure-directing role in controlling the morphology and structure of the obtained ZnO architectures. All of the nanostructured ZnO architectures can be indexed...
Design of Factor XIII V34X activation peptides to control ability to interact with thrombin mutants.

Abstract Thrombin helps to activate Factor XIII (FXIII) by hydrolyzing the R37-G38 peptide bond. The resultant transglutaminase introduces cross-links into the fibrin clot. With the development of therapeutic coagulation factors, there is a need to better understand interactions involving FXIII. Such knowledge will help predict ability to activate FXIII and thus ability to promote/hinder the generation of transglutaminase activity. Kinetic parameters have been determined for a series of thrombin species hydrolyzing the FXIII (28–41) V34X activation peptides (V34, V34L, V34F, and V34P). The V34P substitution introduces PAR4 character into the FXIII, and the V34F exhibits important similarities to the cardioprotective V34L. FXIII activation peptides containing V34, V34L, or V34P could each be accommodated by alanine mutants of thrombin lacking either the W60d or Y60a residue in the 60-insertion loop. By contrast, FXIII V34F AP could be cleaved by thrombin W60dA but not by Y60aA. FXIII V34P is highly reliant on the thrombin W215 platform for its strong substrate properties whereas FXIII V34F AP becomes the first segment that can maintain its K m upon loss of the critical thrombin W215 residue. Interestingly, FXIII V34F AP could also be readily accommodated by thrombin L99A and E217A. Hydrolysis of FXIII V34F AP by thrombin W217A/E217A (WE) was similar to that of FXIII V34L AP whereas WE could not effectively cleave FXIII V34P AP. FXIII V34F and V34P AP show promise for designing FXIII activation systems that are either tolerant of or greatly hindered by the presence of anticoagulant thrombins.