cssi/SciSciGPT-SciSciNet huggingface dataset:
Anterior electrophysiological asymmetries, emotion, and depression: Conceptual and methodological conundrums

Two reports in the last issue of this journal attempted to replicate aspects of our previous studies on anterior electroencephalogram (EEG) asymmetry, affective style, and depression. In this commentary, an overview is provided of our model of anterior asymmetries, affective style, and psychopathology. Emphasis is placed on conceptualizing the prefrontal and anterior temporal activation patterns within a circuit that includes cortical and subcortical structures. The causal status of individual differences in asymmetric activation in the production of affective style and psychopathology is considered. Major emphasis is placed on EEG methods, particularly the need for multiple assessments to obtain estimates of asymmetric activation that better reflect an individual's true score. Issues specific to each of the two articles are also considered. Each of the articles has more consistency with our previously published data than the authors themselves suggest. Recommendations are made for future research to resolve some of the outstanding issues.
Linking research and policy: The case of Ghana's rice trade policy

Agricultural trade policies, in particular import tariffs to protect domestic production, constitute a highly contested field of agricultural policy. In view of the recent focus on âevidence-based policy makingâ in the international development debate, the question arises as to which extent research-based evidence is used in such policy decisions, and which role research plays as compared to other political factors. Against this background, this paper seeks to examine and explain research-policy linkages in the case of rice tariff reform in Ghana. It is based on literature reviews and 70 interviews. The paper uses a historical cultural political economy approach, and reveals that in order to understand the actions of Ghanaâs policy makers, there is a need to go beyond currently used approaches to understanding politics in order to reveal the complex factors that underlie such policy decisions. The paper starts by locating the study in the framework of the recent interest of the international development community in agriculture on the one hand, and in evidence-based policy-making on the other. The paper then reviews the recent literature on then links between research and policy making. After briefly describing the studyâs conceptual framework and methodology, the paper gives an overview of Ghanaâs governance, political dynamics, socio-economic trends, agricultural policies, which provide the setting for research-policy linkages. The presentation of the findings of the study starts with a general description of the links between research and policy that have been observed in agricultural policy-making in Ghana. In order to discover the underlying factors in linking research and policy requires examining particular conceptual lenses (âdiscoursesâ) in Ghana, as well the intricate politics of elections, nationalism, external pressure, and rifts with civic campaigners. To see whether or not the nature of linkages is unique to the rice sector, the report also contrasts the case of rice with on the case of agricultural mechanization.
The Importance of Temporal Dynamics in the Transition From Suicidal Thought to Behavior

May and Klonsky's (2016) meta-analysis highlights a critical limitation of suicide-focused research, the conflation of risk factors for suicide ideation with risk factors for suicidal behavior, and calls for new research aimed at predicting which suicidal individuals will transition to suicide attempts. A critical limitation of existing models of suicide is the lack of attention to nonlinear change processes among relevant risk variables, which could conceal the true nature of the transition from suicidal thought to action. The fluid vulnerability of theory of suicide provides a working model for conceptualizing static versus dynamic aspects of suicide risk over time. Future research focused on understanding the transition from suicidal thought to action should incorporate theoretical models and analytic methods capable of quantifying and describing nonlinear change processes.
Large-Scale Measurement of Absolute Protein Glycosylation Stoichiometry

Protein glycosylation is one of the most important protein modifications. Glycosylation site occupancy alteration has been implicated in human diseases and cancers. However, current glycoproteomic methods focus on the identification and quantification of glycosylated peptides and glycosylation sites but not glycosylation occupancy or glycoform stoichiometry. Here we describe a method for large-scale determination of the absolute glycosylation stoichiometry using three independent relative ratios. Using this method, we determined 117 absolute N-glycosylation occupancies in OVCAR-3 cells. Finally, we investigated the possible functions and the determinants for partial glycosylation.
Atom Probe Tomography – A High Throughput Screening Tool for Atomic Scale Chemistry

The objective of this paper is to examine the challenges and opportunities in high throughput screening of atomic scale chemistry via a technique known as atom probe tomography. While there are numerous methods that exist in the field of throughput screening, even at the nanoscale, most of the effort is on screening properties , rather than chemistry and/or structure. In this overview, we discuss the role atom probe tomography can have as a high throughput screening tool of atomic scale chemistry. Particular emphasis on the study of organic/ biological materials is given along with the needs and challenges to make atom probe tomography more widespread in the field of combinatorial chemistry.
AN EXPERIMENTAL STUDY OF DROPLET BREAKUP IN SUPERSONIC FLOW: THE EFFECT OF LONG-RANGE INTERACTIONS

The paper presents an experimental study of droplet breakup in a rarefied supersonic flow (M = 3) for Weber number over a range from 24 to 450. The work is a continuation of a previous study, in which regimes of aerobreakup in rarefied supersonic flow were identified and shown to differ significantly from those observed in subsonic flow for the same Weber numbers. The emphasis of the present work is to investigate the effect of a foreign object on breakup of a droplet downstream. Remarkable differences are observed and reported in the paper. We discuss the long-range effect of compressible flow pressure field in supersonic flow downstream a cylindrical rod on droplet deformation and breakup.
A Fracture Mechanics Analysis of Underfill Delamination in Flip Chip Packages

Flip chip technology offers a number of advantages over conventional packaging techniques such as smaller size and efficient high-speed signal transmission. However, when assembled on organic substrates, the flip chip needs to be underfilled with a suitable adhesive to enhance the thermo-mechanical reliability of its solder bumps. When such flip chip assemblies are subjected to thermal excursions, the underfill material may delaminate resulting in premature solder bump fatigue failure. Available open literature has extensively focused on underfill delamination propagation due to monotonic loading conditions. However, the information on underfill fatigue delamination propagation is limited. This paper presents an experimental and modeling study on the underfill delamination under monotonic as well as fatigue loading conditions. In this work, the fracture toughness of the passivation-underfill interface has been characterized using the single leg bending test. In addition, a fatigue delamination propagation experiment has been done, and a Paris law type model for delamination propagation has been developed. In parallel, numerical models have been developed to determine the available energy release rate under monotonic loading conditions as well as the range of energy release rate range under thermal cycling conditions. The mode mixity calculations have been carried out using Crack Surface Displacement (CSD) method. Using the models and the experimental data, guidelines against the delamination of the underfill material are developed.© 2005 ASME
Overlapping Mechanisms of Stress-Induced Relapse to Opioid Use Disorder and Chronic Pain: Clinical Implications

Over the past two decades, a steeply growing number of persons with chronic non-cancer pain have been using opioid analgesics chronically to treat it, accompanied by a markedly increased prevalence of individuals with opioid-related misuse, opioid use disorders, emergency department visits, hospitalizations, admissions to drug treatment programs, and drug overdose deaths. This opioid misuse and overdose epidemic calls for well-designed randomized-controlled clinical trials into more skillful and appropriate pain management and for developing effective analgesics that have lower abuse liability and are protective against stress induced by chronic non-cancer pain. However, incomplete knowledge regarding effective approaches to treat various types of pain has been worsened by an under-appreciation of overlapping neurobiological mechanisms of stress, stress-induced relapse to opioid use, and chronic non-cancer pain in patients presenting for care for these conditions. This insufficient knowledge base has unfortunately encouraged common prescription of conveniently available opioid pain-relieving drugs with abuse liability, as opposed to treating underlying problems using team-based multidisciplinary, patient-centered, collaborative-care approaches for addressing pain and co-occurring stress and risk for opioid use disorder. This paper reviews recent neurobiological findings regarding overlapping mechanisms of stress-induced relapse to opioid misuse and chronic non-cancer pain, and then discusses these in the context of key outstanding evidence gaps and clinical-treatment research directions that may be pursued to fill these gaps. Such research directions, if conducted through well-designed randomized-controlled trials, may substantively inform clinical practice in general medical settings on how to effectively care for patients presenting with pain-related distress and these common co-occurring conditions.
Novel polyimide printed circuit boards

Printed circuit boards using polyimide or modified polyimide matrices have been under exploratory study for most of the past decade. The major driving force behind this work has been the need for improved service reliability in the field along with the harsh economic necessity to cut scrap losses in the manufacturer's plant. As a polymer class the polyimides offered improved thermal stability and chemical resistance versus the standard epoxy systems. Thus, it was expected that boards using polyimide matrices would show less change in electrical and physical properties during the manufacturing cycle and also in their daily use. For example, short term exposure of epoxy boards to soldering temperatures can cause the breakdown of the matrix with a resulting change in the physical and electrical properties of the board at that particular spot. Drilling is another manufacturing process where boards are subjected to high temperatures for short terms. Again physical changes such as smearing will occur and the extent of these changes depends primarily on the properties of the polymer matrix; thus, the search for polymer systems having thermal stability both short and long term.
Pediatrics at Mount Sinai

The Department of Pediatrics at The Mount Sinai Hospital was founded more than 120 years ago. During the ensuing years it had five outstanding leaders, Drs. Abraham Jacobi, Henry Koplik, Bela Schick, Horace Hodes, and Kurt Hirschhorn. The evolution of its beginning as a "small" clinic to its present position as one of the outstanding pediatric centers in this country reflects its interest in and devotion to the care of children.
Intrinsic hepatocyte dedifferentiation is accompanied by upregulation of mesenchymal markers, protein sialylation and core alpha 1,6 linked fucosylation

Alterations in N-linked glycosylation have long been associated with cancer but for the most part, the reasons why have remained poorly understood. Here we show that increased core fucosylation is associated with de-differentiation of primary hepatocytes and with the appearance of markers indicative of a transition of cells from an epithelial to a mesenchymal state. This increase in core fucosylation was associated with increased levels of two enzymes involved in α-1,6 linked fucosylation, GDP-mannose 4, 6-dehydratase (Gmds) and to a lesser extent fucosyltransferase 8 (Fut8). In addition, the activation of cancer-associated cellular signaling pathways in primary rat hepatocytes can increase core fucosylation and induce additional glycoform alterations on hepatocyte proteins. Specifically, we show that increased levels of protein sialylation and α-1,6-linked core fucosylation are observed following activation of the β-catenin pathway. Activation of the Akt signaling pathway or induction of hypoxia also results in increased levels of fucosylation and sialylation. We believe that this knowledge will help in the better understanding of the genetic factors associated with altered glycosylation and may allow for the development of more clinically relevant biomarkers.
The Roles of Stereotypes and Group Norms on Perceptions of Bodily Attractiveness

Research on social stereotypes has enjoyed a long history in psychology and related fields. Although many definitions of a stereotype exist, researchers generally believe that ‘stereotypes are qualities perceived to be associated with particular groups or categories of people’ (Schneider, 2004: 24). Many have used stereotypes to understand the impact of attractiveness on social situations or personality (Eagly, Ashmore, Makhijani, & Longo, 1991;Feingold, 1992). The overwhelming majority of research on the attractiveness stereotype has focused on how individuals perceive attractive people or how well attractiveness correlates with a range of traits or behaviours. However, the social processes that contribute to attractiveness stereotyping are of equal theoretical importance.
Innovation and the Profitability Imperative: Consequences on the Formation of the Firm’s Knowledge Capital

In neoclassical economics, the firm is seen as a ‘black box’, i.e. an entity receiving flows of raw materials and turning out flows of processed or finished products. The purpose of such an entity is to maximize its profit, being limited only by its resources. However, since the 1960s, this restrictive vision of the firm’s goals has been largely questioned and has been commonly replaced by a more complex spectrum of objectives.
Cartographic Japan: A History in Maps

Karen Wigen, Sugimoto Fumiko, and Cary Karacas, eds. Chicago, IL: University of Chicago Press, 2016. xii and 269 pp., maps, illustrations, table, notes, bibliography, index. $45.00 cloth (ISBN 978-...
Winter bikesharing in US: User willingness, and operator’s challenges and best practices

Abstract Bikesharing is an emerging sustainable transportation alternative which is gaining attention and demand since the launch of the third-generation bikeshare system in the United States in 2007. As of 2015, there were 74 U.S. cities operating bikeshare programs. More than half of these programs are seasonal, meaning they shut down their operations for winter. This study focuses on gathering more knowledge and information relating to winter bikesharing for the United States in terms of understanding users’ willingness to use bikeshare programs in harsh winters, and operators’ strategies, challenges and best practices for providing bikeshare operations without interruption in cold U.S. cities. Great Rides Bikeshare users in Fargo, North Dakota, were surveyed in October 2015 to understand their willingness to use the bikeshare program in winter and determine factors influencing their ridership. Based on 654 returned survey responses, significant number (70%–95%) of regular, occasional, and infrequent bikeshare users expressed their willingness to use bikeshare program in winter; further, the willingness increased among users in situations when bike paths and sidewalks could be cleared of snow and ice. A second survey was conducted in February 2016 with bikeshare program operators located in other cold U.S. cities that expect snow events, freezing temperatures, and other adverse winter weather conditions and were operational for the 2015–2016 winter. Expected ridership for bikeshare program during the winter has been observed anywhere between 10 and 30% of peak summer ridership. Winter bikeshare operational strategies, challenges, and best practices were gathered from 10 out of 14 bikeshare programs that were operated through 2015–2016 winter. Results from this study can be useful to researchers, and bikeshare operators who want to implement year-round bikeshare operations in cold cities with winter conditions.
In Reply: Submassive pulmonary embolism.

We thank Dr. Katyal for his thoughtful comments. Dr. Katyal points out that the grade of recommendation for thrombolysis in patients with massive pulmonary embolism was upgraded from 2C to 2B in the 2016 American College of Chest Physicians (ACCP) guidelines[1][1] compared with the 2012 guidelines[
High-resolution direct printing of molten-metal using electrohydrodynamic jet plotting

Abstract In this paper, a high-resolution direct printing process was developed for molten metal using Electrohydrodynamic (EHD) printing technology. The effect of the critical printing conditions, such as voltage and printing speed, on the printing process was characterized. Compared with direct extrusion using pneumatic pressure, the EHD printing can effectively reduce the dimension of the printed filament down to less than 50 μm with better quality of the printed features. We successfully applied EHD printing to print high-resolution 2D patterns and some high aspect-to-ratio 3D structures, which demonstrated the potential capabilities of EHD printing process in producing fine metal structures.
Constitutive expression of IL-22 in the human intervertebral disc and its reduction by exposure to pro-inflammatory cytokines in vitro.

The importance of cytokines in disc degeneration is well recognized. Little is known about IL-22 expression in the human intervertebral disc. We investigated IL-22 immuno-localization in disc tissu...
Addressing the Communication and Other Needs of Persons With Severe Disabilities Through Engaged Interprofessional Teams: Introduction to a Clinical Forum.

Purpose Interprofessional collaborative practice (IPCP) is introduced as a viable and preferred clinical methodology for speech-language pathologists and others serving persons with severe disabili...
Effect of the meropenem MIC on the killing activity of meropenem and polymyxin B in combination against KPC-producing Klebsiella pneumoniae

Effect of the meropenem MIC on the killing activity of meropenem and polymyxin B in combination against KPC-producing Klebsiella pneumoniae
Choosing a Cantilever for In Situ Atomic Force Microscopy

What is the best cantilever for intermittent contact mode (often called Tapping Mode™) atomic force microscope (AFM) imaging under water? This is a question I hear often and one that recently generated some interesting discussion on an AFM newsgroup (more on the newsgroup below). The ability of the AFM to image samples En physiologically relevant environments has made it a popular technique in the biological sciences. However, because scanning the AFM tip in contact mode easily perturbs many biological samples, it was the advent of intermittent contact modes that lead to AFM's widespread use in biology.
Reconfigurable reflectarray antenna for microwave detection and imaging

This paper presents a design of a reconfigurable reflectarray antenna. A reconfigurable unit cell element based on varactor diode is first designed, fabricated and tested at X-band. Measured reflection phase range equal to 305° is obtained by tuning the diode biasing voltage. A reconfigurable reflectarray antenna of 10 × 10 elements is designed based on the proposed unit cell element. A prototype of the reflectarray antenna is fabricated and tested to validate the ability of pattern control. This reflectarray is used in a prototype compressive sensing detection system to detect threat objects in shoes.
"Workplace Bullying, Psychopathy, and Businesspersons’ Ethical Issue Recognition"

Workplace bullying can potentially spiral into numerous counterproductive behaviors and negative work outcomes in organizations. Therefore, the purpose of this study was to determine the degree to ...
Reducing diabetes risk at an early age.

A large retrospective study involving 62,565 Danish men shows that those who have been overweight in childhood have a lower risk of having type 2 diabetes in adulthood if they had remission of overweight before 13 years of age.
Effects of Mutation for ALS-Inhibitor Resistance on ALS Activity in Resistant and Susceptible Near-Isonuclear Lactuca Lines

The biochemical and physiological effects of target site mutation for ALS-inhibitor resistance were evaluated using chlorsulfuron-resistant (R) and chlorsulfuronsusceptible (S) near isonuclear ‘Bibb’ lettuce (Lactuca sativa L.) lines. The near isonuclear lines (isolines) were developed by backcrossing the resistance allele from a chlorsulfuronresistant prickly lettuce (Lactuca serriola L.) biotype into Bibb lettuce. The specific activity of ALS from the R Bibb isoline was 46% of the specific activity of ALS isolated from the S Bibb isoline, suggesting that there are detrimental effects of the mutation for resistance on enzyme function, expression, or stability. The Km (pyruvate) values of ALS isolated from R Bibb and S Bibb were similar, 7.3 and 11.1 mM, respectively, suggesting that the mutation for resistance did not alter pyruvate binding on the ALS enzyme. ALS activity from both R and S Bibb isolines was inhibited by valine, leucine, and isoleucine. However, ALS from R plants was less sensitive to feedback inhibition by the individual amino acids than ALS from S plants. Concentrations of valine, leucine, and isoleucine were about 1.5 times higher in R seed than in S seed, and concentrations of valine and leucine in R Bibb lettuce leaves were 1.3 and 1.6 times higher, respectively, than in leaves of the S isoline. Therefore, mutation for resistance to ALS-inhibiting herbicides may alter regulation of branched chain amino acid synthesis.
Abstract WP320: Blood Pressure Reduction During Endovascular Stroke Therapy is Associated With Poor Functional Outcome

Background: Endovascular therapy (EVT) has been demonstrated to be beneficial regardless of baseline blood pressure (BP). However, questions concerning optimal BP management during EVT remain unans...
Autonomous Indoor Pathfinding Using Neural Network in Complex Scenes

Navigation to a specific destination indoors can be a challenge due to different reasons such as visual impairment, unknown environments, etc. There has been much work done to solve this issue such as indoor positioning systems, navigation using sensors and even using a robotic guide. In this paper, a novel and straightforward method of path planning (including object avoidance) is presented as a way of navigating to a desired location within a complex environment. The system proposed uses the combination of depth information from an RGB-D camera and the object information from a Neural Network based object identification technique, to efficiently calculate and plan a path in real-time, to a pre-specified destination. Persons to be helped are identified using object detection, and the most practical path to the desired destination is calculated. The path information would be sent to the handheld device of the person being helped in the suitable form of interface, such as visual, audio, etc. The surveillance type nature of the system enables it to help multiple persons in the same area. The model was tested in a controlled environment with one individual person being guided to nearby specified locations. While the testing showed promising results, strong conclusions are yet to be made with the current system.
A pedagogical approach to estimating the CO2 budget of magmas

On a planetary scale, the carbon cycle describes the movement of carbon between the atmosphere and the deep Earth. Carbon species are involved in diverse Earth processes, ranging from sedimentary, metamorphic and igneous petrology to the long-term viability of life at the Earth9s surface. Volcanoes, and their associated magmatic systems, represent the interface through which carbon is transferred from the deep Earth to the surface. Thus, quantifying the CO2 budget of volcanic systems is necessary for understanding the deep carbon cycle and, concomitantly, the CO2 budget of the near surface, including the atmosphere. In this review, Kilauea volcano (Hawaii) is used as a case study to illustrate simple calculations that can account for processes that affect the amount and distribution of CO2 in this relatively well-studied volcanic system. These processes include methods to estimate the concentration of CO2 in a melt derived by partial melting of a source material, enrichment of CO2 in the melt during fractional crystallization, exsolution of CO2 from a fluid-saturated melt, trapping and post-entrapment modification of melt inclusions, and outgassing from the volcanic edifice. Our goal in this review is to provide straightforward example calculations that can be used to derive first-order estimates regarding processes that control the CO2 budgets of magmas and that can be incorporated into global carbon cycle models.
Characteristics and Outcomes of Patients With Aortic Stenosis and Chronic Kidney Disease.

Background We sought to study longer term survival in patients with aortic stenosis (AS) and nondialysis chronic kidney disease (CKD). Methods and Results We studied 839 patients (aged 78±9 years a...
Alcohol Use Problems, Posttraumatic Stress Disorder, and Suicide Risk Among Trauma-Exposed Firefighters.

Alcohol use problems are associated with suicidal desire and may provide an avenue to suicidal ideation and behavior. However, the influence of posttraumatic stress disorder (PTSD) on the nature of the relationship between alcohol use problems and suicide risk is not well understood. In particular, the potential for PTSD to moderate the association between alcohol use problems and suicide risk remains unexplored. The present study investigated the main and interactive effects of alcohol use problems (Alcohol Use Disorders Identification Test) and PTSD symptoms (PTSD Checklist for DSM-5) on suicide risk (Suicide Behaviors Questionnaire-Revised) in a sample of 632 trauma-exposed firefighters (93.5% men; Mage = 38.44 years, SD = 8.59). Hierarchical logistic regression analyses evaluated whether the main and interactive effects of PTSD symptom severity and alcohol use disorders were significantly related to suicide risk, above and beyond age and cumulative trauma. The main effects of PTSD symptom severity (odds ratio, 1.76; p 0.05). A secondary, exploratory aim demonstrated that all PTSD symptom clusters significantly positively predicted suicide risk (p's 0.05). Theoretical and clinical implications are discussed as they relate to the importance of screening for PTSD and alcohol use disorder among firefighter populations.
P123 A Qualitative Investigation into Nutrition Literacy Assessment in Outpatient Clinics

Background Nutrition literacy is a unique subset of health literacy, a leading predictor of poor health outcomes. Understanding a patient's nutrition literacy may help dietitians provide interventions tailored to a patient's nutrition knowledge weaknesses. While tools exist to evaluate nutrition literacy, it is unclear whether dietitians currently assess patients for nutrition literacy. Objective To examine nutrition literacy assessment among practicing outpatient dietitians, barriers to implementing a nutrition literacy survey into clinical practice, and possible solutions to these barriers. Study Design, Settings, Participants Semi-structured interviews, divided into four sampling frames, with dietitians (n = 28) from multiple outpatient settings were conducted across two Midwestern states. Similar interviews were conducted with outpatient clinic managers (n = 7), providing a wider viewpoint. Measurable Outcome/Analysis Questions addressed clinic work flow, assessing nutrition literacy, and barriers to implementing a survey into practice. All interviews were transcribed, coded, and analyzed by trained study personnel. Results All dietitians stated they use no nutrition literacy assessment tools in clinical practice; subjective assessments are used. Barriers to survey implementation included time to complete the survey (79%/n = 22 of interviewees), logistics in administering the survey (75%/n = 21), patient motivation (75%/n = 21), literacy levels of patients (54%/n = 15), and clinic staff support (32/n = 9). Clinic managers stated barriers to survey implementation included patient motivation (86%/n = 6), devoting staff to a non-revenue generating task (71%/n = 5), logistics in administering the survey (71%/n = 5), and time to complete the survey (57%/n = 4). Solutions include survey administration prior to the patient's appointment (79% of dietitians/n = 22, 86% of managers/n = 6), motivating patients to complete the survey prior to their visit (29%/n = 8, 100%/n = 7), and reducing survey length (21%/n = 6, 43%/n = 3). Conclusion While multiple barriers to evaluating nutrition literacy in clinical settings exist, potential solutions to these barriers exist. Further research on the implementation of nutrition literacy assessment in the outpatient clinic setting is needed.
Beyond balance and mobility, contributions of cognitive function to falls in older adults with cardiovascular disease.

Objectives Older adults with cardiovascular disease (CVD) are at risk for cognitive impairment. Cognitive function is associated with falls in older adults however it is unknown if a relationship exists between cognitive function and falls in CVD. The aim of this study was to examine the contributions of cognitive function on falls in older adults with CVD. Methods A secondary analysis was performed on data from the Health and Retirement Study cohort 2010 (N=3413) of older adults with CVD. Group assignment was based on falls history (yes/no) within the two years prior to the survey. Demographic (age, education, gender, marital status), physical (strength, balance, physical activity, and mobility) and cognitive (immediate and delayed recall, orientation, semantic verbal fluency, numeracy) information was extracted to characterize the sample. Comparisons between groups were completed for all of these variables. Logistic regression was performed to examine associations between each of the cognitive variables and falls while controlling for age, gender, marital status, education, and BMI. Results Demographic (age, gender, marital status, and education), physical (grip strength, tandem stance time, and gait speed), and cognitive (orientation, immediate and delayed recall) variables differed by falls history (p<0.05). After controlling for confounding, immediate recall was the only significant predictor of falls (OR=1.09, 95% CI=1.01-1.17) (Nagelkerke R2=0.037, χ2=35.14, p<0.05) with correctly classifying 65.9% of cases. Conclusions In older adults with CVD, cognitive and physical functions are more impaired in those with a falls history. Screening for cognitive function, specifically immediate recall, should be a part of the management of falls in this population.
Mycotoxin Occurrence in Oak Acorn Species Native to Tennessee

Agricultural plants and domestic animals are subject to mycotoxin contamination or infection, respectively, during unusually wet or dry growing seasons. This study was designed to assay mycotoxin levels in a major wildlife food source. Acorn and corn samples were collected at the Ames Plantation in Grand Junction, Tennessee, from both bottomland and upland regions. Samples were gathered during Fall 1998 after adroughty summer. Forty-eight acorn samples were tested, using thin-layer chromatography, for six different toxins at the Animal Disease Diagnostic Laboratory at Purdue University. This determined the concentrations and types of mycotoxins present in each sample. Two of the six toxins showed up regularly and at fairly high concentrations throughout the samples. Acorn samples closer to cornfields yielded higher frequencies of one of the toxins. Wildlife that eat these acorns are receiving levels of mycotoxins at least twice that of the recommended levels for any domestic animal. Further research needs to be conducted during a year when there is little or no environmental stress to see if the 1998 acorn samples showed unusually high levels of toxins. These toxins can pose a threat to wildlife, and more research should be carried out to test the extent to which wildlife are exposed to and damaged by these toxins.
The ocean-going noni, or Indian Mulberry (Morinda citrifolia, Rubiaceae) and some of its “colorful” relatives

The genus Morinda embraces about 80 species, mostly of Old World origin.M. citrifolia L. (southern Asia Australia), noted as a source of dye and edible leaves, has buoyant seeds that float for many months and commonly appears in the Pacific and also in tropical America where M. royoc L., pina de raton, is indigenous, inhabits inland hammocks and pinelands as well as seacoasts, and is also one of the floating-seed morindas. There are brief references to its use for dyeing in the Cayman Islands and Yucatan. BothM. citrifolia andM. royoc have sundry folk-remedy uses.M. parvifolia Bartl. has antitumor/antileukemic activity. High intake of selenium byM. reticulata Benth. has poisoned horses in Australia. In the Philippines, there is new interest in the wood ofM. citrifolia. It is hard and of beautiful grain.
Therapeutic remodeling of CBP transcription factor complex controls oncogenic gene expression in acute myeloid leukemia

Dysregulated gene expression is one of the most prevalent features in human cancers. Here, we show that most subtypes of acute myeloid leukemia (AML) depend on the aberrant assembly of the MYB transcriptional co-activator complex. By rapid and selective peptidomimetic interference with the binding of CBP/P300 to MYB, but not CREB or MLL, we find that the leukemic functions of MYB are mediated by CBP/P300-mediated co-activation of a distinct set of transcriptional factor complexes that are aberrantly assembled with MYB in AML cells. This therapeutic remodeling is accompanied by dynamic redistribution of CBP/P300 complexes to genes that control cellular differentiation and growth. We propose that convergently organized transcription factor complexes in AML cells control oncogenic gene expression programs. These findings establish a compelling strategy for pharmacologic reprogramming of oncogenic gene expression that supports its targeting for leukemias and possibly other human cancers caused by dysregulated gene control.
The effect of the chosen distribution form on reaction probability estimates from drop-weight impact results

The consequences of choosing one distribution form in the analysis of drop-weight impact results were explored, and the importance of reporting both the L50 and the distribution spread-parameter fo...
Publication productivity (H-Index) among pediatric dermatologists in the United States.

BACKGROUND/OBJECTIVE The h-index is a measure of research achievement. Individuals with similar h-indices should be equivalent in terms of scientific impact. However, this value is inherently biased toward fields with higher visibility and readership. To utilize the power of h-indices in predicting future research success and as a benchmark for academic advancement, niche fields like pediatric dermatology must be examined independently. METHODS Publicly available data were examined. A list of current pediatric dermatologists were obtained from the Society for Pediatric Dermatology's member directory. The following demographic information was obtained: fellowship certification year, PhD status, prior pediatric residency training, state/region, practice setting, academic appointment, number of publications, and h-index. Descriptive and analytic statistics were calculated. RESULTS A total of 317 pediatric dermatologists were included. Practice setting distribution was as follows: 54.3% academic, 32.5% non-academic, and 13.3% combined. H-index differed significantly based on pediatric dermatology certification year (P < .001), increasing as time from certification increased. Those in academics had higher h-indices than those in both non-academic and combined practice settings (P < .001 and .007, respectively). Professors (25.0) had higher h-indices than associate professors (11.0), who had higher h-indices than assistant professors (4.4) (P < .001). CONCLUSIONS H-index increased with increasing academic rank and was highest among those working in academics. For pediatric dermatologists considering application for promotion, the h-index for each level can serve as a useful benchmark to guide decision-making.
Longitudinal changes in blood-based biomarkers in chronic moderate to severe traumatic brain injury: preliminary findings.

Objectives: This longitudinal study aims at 1) providing preliminary evidence of changes in blood-based biomarkers across time in chronic TBI and 2) relating these changes to outcome measures and c...
State emotion modulation and loss-of-control eating in individuals with obesity: A preliminary ecological momentary assessment study

Abstract There is ample evidence linking broad trait emotion regulation deficits and negative affect with loss-of-control (LOC)-eating among individuals with obesity and binge eating, however, few studies have examined emotion regulation at the state-level. Within and across day fluctuations in the ability to modulate emotion (or regulate emotional and behavioral responses), one facet of state emotion regulation, may be a more robust momentary predictor of LOC-eating than momentary negative affect and trait emotion regulation ability. As such, the current study tested if daily emotion modulation, and daily variability in emotion modulation differed on days with and without LOC-eating episodes, and if momentary emotion modulation was associated with subsequent LOC-eating episodes. For two weeks individuals (N = 14) with obesity and binge eating completed surveys as part of an ecological momentary assessment study. Participants reported on current ability to modulate emotion, LOC-eating, and current negative affect. On LOC-eating days compared to non-LOC-eating days, ability to modulate emotion was poorer (β =0.10, p
Quantum Hall Ground States and Regular Graph

We introduce and develop a methodology to construct and characterize model fractional qunatum Hall ground states via regular graphs. In particular, we show that every quantum Hall ground state is essentially a superposition of regular graphs. The model FQH ground states we construct will all automatically have a $(k,r)$ clustering property. For a subclass of the construction, a model Hamiltonian is provided which is a finer modification of Haldane's pseudopotential.
Sustaining curiosity: Reggio-Emilia inspired learning

In many contexts, early educators are pressured to adopt narrow, skill-based curricular approaches and accompanying standards and measures of accountability. Alternatively, other educators infuse h...
Review of The Litigator's Guide to Expert Witnesses

This book is written by a partner in the prestigious Toronto law firm of McCarthy TCrault and a partner in the well-known accounting firm of Arthur Anderson. Mr. Freiman, the senior author, holds a Ph.D. from Stanford University in English, a subject he taught for a number of years at the university level in England, the United States and Canada. Mr. Berenblut graduated from the London School of Economics and has been an expert witness, an arbitrator in connection with many issues involving economic damage quantification. Dr. Freiman and Mr. Berenblut are the editors of this multi-authored book and they also have contributed two major chapters. The book consists of 23 chapters covering general principles of expert testimony, from accounting to psychiatry.
Sperm production in boars after nine generations of selection for increased weight of testis

Body, testis, and epididymis weights were recorded and homogenization-resistant sperm nuclei were counted to determine daily sperm production and the number of sperm stored within the cauda epididymis (CAUDASP) in 145 boars of a control line (C) and 128 boars of a line selected for increased predicted weight of testis (TS) at 150 d of age. Random samples of boars were evaluated at five ages between 70 and 450 d in Generation 8 and 15 ages between 70 and 296 d in Generation 9. Data were analyzed using an animal model that included the fixed effect of line and the linear, quadratic, and cubic effects of age. Variance components were estimated using a DFREML algorithm. Boars of the TS and C line did not differ in body weight (P > .05) in Generation 8. In Generation 9, boars of line TS were heavier between 118 and 198 d of age (P .05). The increase in organ weights for the testes and epididymides between 70 and 160 d of age were greater (P < .01) for boars of line TS in each generation, and differences between the lines in testis weights established around puberty were maintained at 450 d of age. Daily sperm production and CAUDASP increased more rapidly at younger ages and plateaued at greater values (P < .05) in boars of line TS. At ages less than 200 d, boars of line TS produced more sperm per gram of parenchyma than control boars.(ABSTRACT TRUNCATED AT 250 WORDS)
Fano resonance structural color in patterned dielectric surfaces

Fano resonance is used to generate structural color in microscopically structured dielectric materials that can be tuned through the visible spectrum.
Pregnancy complicated by spontaneous suprarenal and ovarian venous hemorrhage

An 1%year-old primigravida was hospitalized in the thirty-eighth week of pregnancy at 9:30 A.M., Sept. 30, 1956. The prenatal course had been uneventful until September 29. Then the patient experienced transitory, sharp pain in the right costovertebral angle. Since it disappeared quickly, she disregarded it. Approximately 24 hours later the excruciating pain reappeared suddenly as she sat down in a chair. Nearly two hours later, when hospitalized, the blood pressure was 110/90, the pulse 60 per minute, and the temperature 98.6” F. The skin was dry with goocl turgor. The mucous membranes were moderately pale. The head, neck, chest, heart, and lungs appeared essentially normal. The uterine fundus was soft, nontender, and within 4 cm. of the xiphoid process. The baby presented by the vertex. One observer thought the fetal heartbeat was faint for a short time. Light pressure over the right kitlney posteriorly reproducecl much discomfort. The cervix was long, uneffaced, and closed. Rectal examination added no information. There was no etlema of the extremities. The tentative diagnosis was renal colic with obstruction due to a stone, versus torsion or rupture of a viacus as a seconll choice.
An integrated hydrologic Bayesian multimodel combination framework: Confronting input, parameter, and model structural uncertainty in hydrologic prediction

[1] The conventional treatment of uncertainty in rainfall-runoff modeling primarily attributes uncertainty in the input-output representation of the model to uncertainty in the model parameters without explicitly addressing the input, output, and model structural uncertainties. This paper presents a new framework, the Integrated Bayesian Uncertainty Estimator (IBUNE), to account for the major uncertainties of hydrologic rainfall-runoff predictions explicitly. IBUNE distinguishes between the various sources of uncertainty including parameter, input, and model structural uncertainty. An input error model in the form of a Gaussian multiplier has been introduced within IBUNE. These multipliers are assumed to be drawn from an identical distribution with an unknown mean and variance which were estimated along with other hydrological model parameters by a Monte Carlo Markov Chain (MCMC) scheme. IBUNE also includes the Bayesian model averaging (BMA) scheme which is employed to further improve the prediction skill and address model structural uncertainty using multiple model outputs. A series of case studies using three rainfall-runoff models to predict the streamflow in the Leaf River basin, Mississippi, are used to examine the necessity and usefulness of this technique. The results suggest that ignoring either input forcings error or model structural uncertainty will lead to unrealistic model simulations and incorrect uncertainty bounds.
The political economy of urban ruins: Redeveloping Shanghai

This essay analyzes the political economy of the urban ruins captured in Greg Girard's photo album Phantom Shanghai. Rather than being marginal, irrelevant or merely objects for nostalgia, the ruins of buildings produced by real estate speculation offer crucial insights into the workings of the urban political economy and reflect wider trends of urban governance. Examining how building ruins come about in the first place and how they are represented in visual media can help us better understand the processes of urbanization and place making, and the central role of destruction in contemporary Chinese urbanism. This essay illustrates this point by analyzing the economic function, political legitimation and cultural significance of demolitions and ruins in urban China.
International Organizations: Introduction to international organizations

All international organizations exists in the conceptual and legal space between state sovereignty and legal obligation. They are created by the commitments made by sovereign states, and their purpose is to bind those states to their commitments. This chapter examines three forces in world politics: the commitments states make to international organizations, the choices states make regarding compliance and non-compliance with those commitments, and the powers of enforcement held by each international organization. Some international organizations are able to coerce their member states into complying with their commitments: for instance, the UN Security Council has a military component and the IMF has coercive leverage over its borrowers. But far more commonly they are left to find ways to cajole or induce compliance from their members. In each organization, the particular relationship between obligation, compliance, and enforcement is different, and these differences create interesting patterns of politics. The main problems of international economics and international politics are at some level also problems of international organization. As interdependence increases, the importance of international organizations increases with it. We find international organizations in one form or another at the heart of all of the political and economic challenges of the twenty-first century. From international credit markets to endangered species to torture, today's leading controversies all involve some measure of international cooperation and commitment, managed through a formalized international organization (IO). Some IOs work well and some work hardly at all; some need reform, some need abolishing, and some need strengthening.