cssi/SciSciGPT-SciSciNet huggingface dataset:
RETRIEVING RIVER ATTRIBUTES FROM REMOTELY SENSED DATA: AN EXPERIMENTAL EVALUATION BASED ON FIELD SPECTROSCOPY AT THE OUTDOOR STREAM LAB

This paper summarizes experiments conducted at the Outdoor Stream Lab to gain insight on the relationships between a channel's spectral characteristics and the river attributes of interest to scientists and managers. Improved understanding of these connections would advance the application of remote sensing to fluvial systems. Motivated by this objective, we examined the following: (i) interactions among local hydraulics, water surface roughness and surface reflectance; and (ii) the influence of periphyton development and streambed disturbance on bottom reflectance. These experiments could thus lead to novel methods for inferring flow velocity and substrate type, respectively, from passive optical image data. Our initial results indicate the following: (i) water surface reflectance can compromise spectrally based depth retrieval by reducing the range of useful wavelengths and weakening correlations between band ratios and depth, implying that removing the surface-reflected component of the total radiance could facilitate bathymetric mapping; (ii) water surface roughness was influenced by local hydraulics and was positively correlated with water surface reflectance, suggesting that observations of surface reflectance could be used to infer flow velocities; (iii) substrate spectral characteristics were influenced by the degree of periphyton development, implying that algal biomass might be estimated from remotely sensed data; and (iv) similarly, bottom reflectance differed significantly for intact versus disturbed substrates, suggesting that areas of streambed disturbance might be identified via remote sensing. Future work will focus on further elucidating connections between surface reflectance, water surface texture and flow velocity, and developing quantitative relationships between bottom reflectance, periphyton abundance and the degree of streambed disturbance. Copyright © 2013 John Wiley & Sons, Ltd.
TRANSNATIONAL MIGRATION AND THE GENDER POLITICS OF SCALE: INDONESIAN DOMESTIC WORKERS IN SAUDI ARABIA

Recent research has begun to explore the dynamics of transnational migration from a feminist perspective, and studies of migrant domestic workers have played a prominent role in pushing forward this work. Emerging simultaneously, but largely separately, are explicit debates within geography about the politics of scale, the social construction of scale, and the gender dimensions of scale. This article develops an analysis of the gender politics of the production of scale, specifically, the “transnationalisation” of Indonesian activist approaches to overseas migrant domestic workers’ issues. Based on fieldwork in an Indonesian community in West Java that has recently become a sending area for migrants to Saudi Arabia and interviews with activists representing Indonesian migrant women, the article examines the various gender-specific ways in which migrant women’s rights activists construct and deploy the scales of the body, the nation and the transnational. It argues that activist approaches to migrant domestic workers’ rights and the ways in which activists mobilise migrant women’s narratives represent sophisticated feminist theoretical approaches to scale. By identifying and exploring the scale theory embedded in activist strategies, the analysis highlights the imbrication of feminist theory with practice, and underscores activists’ agency in producing the meanings of specific scales. In so doing, the article is aimed more broadly at elaborating the ambivalent relationship between feminist activism/ theory and transnationalism.
Sister Chromatid Exchange Analysis in Cultured Peripheral Blood Leukocytes of the Coldwater Marine Fish, Pacific Staghorn Sculpin (Leptocottus Armatus): A Feasible System for Assessing Genotoxic Marine Pollutants

The genotoxicity of environmental contaminants and test compounds to aquatic and marine fish has primarily been assessed by in vivo techniques that require sacrifice of the test organism for analysis. The major objective of this research was to develop an in vitro sister chromatid exchange (SCE) assay which would utilize cultured peripheral blood leukocytes (PBLs) of a coldwater marine fish species. Use of PBLs in cytogenetic genotoxicity tests has several advantages, the major one being that the experimental fish need not be sacrificed for sample collection. In addition, this nondestructive method of tissue collection permits the investigator to take multiple samples from a single individual and thereby allows the use of an individual as its own control and to monitor its SCE frequency over time.
A performance comparison study of ad hoc wireless multicast protocols

In this paper we investigate the performance of multicast routing protocols in wireless mobile ad hoc networks. An ad hoc network is composed of mobile nodes without the presence of a wired support infrastructure. In this environment, routing/multicasting protocols are faced with the challenge of producing multihop routes under host mobility and bandwidth constraints. In recent years, a number of new multicast protocols of different styles have been proposed for ad hoc networks. However, systematic performance evaluations and comparative analysis of these protocols in a common realistic environment has not yet been performed. In this study, we simulate a set of representative wireless ad hoc multicast protocols and evaluate them in various network scenarios. The relative strengths, weaknesses, and applicability of each multicast protocol to diverse situations are studied and discussed.
Epidemiology of Critical Care Syndromes, Organ Failures, and Life-Support Interventions in a Suburban US Community

Background ICU services represent a significant and increasing proportion of medical care. Population-based epidemiologic studies are essential to inform physicians and policymakers about current and future ICU demands. We aimed to determine the incidence of critical care syndromes, organ failures, and life-support interventions in a defined US suburban community with unrestricted access to critical care services. Methods This population-based observational cohort from January 1 to December 31, 2006, in Olmsted County, Minnesota, included all consecutive critically ill adult residents admitted to the ICU. Main outcomes were incidence of critical care syndromes, life-support interventions, and organ failures as defined by standard criteria. Incidences are reported per 100,000 population (95% CIs) and were age adjusted to the 2006 US population. Results A total of 1,707 ICU admissions were identified from 1,461 patients. Incidences of critical care syndromes were respiratory failure, 430 (390-470); acute kidney injury, 290 (257-323); severe sepsis, 286 (253-319); all-cause shock, 194 (167-221); acute lung injury, 86 (68-105); all-cause coma, 43 (30-55); and overt disseminated intravascular coagulation, 18 (10-26). Incidence of mechanical ventilation was invasive, 310 (276-344); noninvasive, 180 (154-206); vasopressors and inotropes, 183(155-208). Renal replacement therapy incidence was 96 (77-116). Of the cohort, 1,330 patients (91%) survived to hospital discharge. Short- and long-term survival decreased by the number of failing organs. Conclusions In a suburban US community with high access to critical care services, cumulative incidences of critical care syndromes and life-support interventions were higher than previously reported. The results of this study have important implications for future planning of critical care delivery.
Process evaluation of Healthy Bodies, Healthy Souls: a church-based health intervention program in Baltimore City

Soaring obesity rates in the United States demand comprehensive health intervention strategies that simultaneously address dietary patterns, physical activity, psychosocial factors and the food environment. Healthy Bodies, Healthy Souls (HBHS) is a church-based, community-participatory, cluster-randomized health intervention trial conducted in Baltimore City to reduce diabetes risk among urban African Americans by promoting healthy dietary intake, increased physical activity and improvement to the church food environment. HBHS was organized into five 3-8-week phases: Healthy Beverages, Healthy Desserts, Healthy Cooking, Healthy Snacking and Eating Out and Physical Activity. A three-part process evaluation was adopted to evaluate implementation success: an in-church instrument to assess the reach, dose delivered and fidelity of interactive sessions; a post-intervention exposure survey to assess individual-level dose received in a sample of congregants and an evaluation form to assess the church food environment. Print materials were implemented with moderate to high fidelity and high dose. Program reach was low, which may reflect inaccuracies in church attendance rather than study implementation issues. Intervention components with the greatest dose received were giveaways (42.0-61.7%), followed by taste tests (48.7-53.7%) and posters (34.3-65.0%). The dose received of general program information was moderate to high. The results indicate successful implementation of the HBHS program.
Dynamic discovery and coordination of agent-based semantic Web services

We describe about dynamic discovery and coordination of agent-based semantic Web services. Matchmaking and brokering are multiagent coordination mechanisms for Web services. Both have performance trade-offs, but the Web Ontology Language for Semantic Web Services (OWL-S) can handle extensions that address some of the shortcomings. We focus on the broker, analyzing both its interaction protocol and reasoning tasks. We also describe OWL-S's exec extensions, detail their implementation's basic features, and explain how these features address the broker's reasoning problems.
The effect of background and illumination on color identification of real, 3D objects

For the surface reflectance of an object to be a useful cue to object identity, judgments of its color should remain stable across changes in the object's environment. In 2D scenes, there is general consensus that color judgments are much more stable across illumination changes than background changes. Here we investigate whether these findings generalize to real 3D objects. Observers made color matches to cubes as we independently varied both the illumination impinging on the cube and the 3D background of the cube. As in 2D scenes, we found relatively high but imperfect stability of color judgments under an illuminant shift. In contrast to 2D scenes, we found that background had little effect on average color judgments. In addition, variability of color judgments was increased by an illuminant shift and decreased by embedding the cube within a background. Taken together, these results suggest that in real 3D scenes with ample cues to object segregation, the addition of a background may improve stability of color identification.
Ellison's Rinehart and Count Basie's: Invisible Man and ‘Harvard Blues’

How does access to this work benefit you? Let us know! Publisher's Statement This is a pre-copyedited, author-produced PDF of an article accepted for publication in Notes & Queries following peer review. The version of record "Ellison's Rinehart and Count Basie's: Invisible Man and 'Harvard Blues.'" Notes & Queries 54:2 (2007), 181-83 is available online at: http://nq.oxfordjournals.org/content/54/2/181.extract Follow this and additional works at: http://engagedscholarship.csuohio.edu/cleng_facpub Part of the Literature in English, North America Commons
Are the Kaldor–Verdoorn Laws Applicable in the Newly Industrializing Countries?

The Kaldor‐Verdoorn “laws,” the focus of this work, are a set of stylized facts which attempt to describe growth in an economy. This paper tests these stylized facts using macroeconomic data from newly industrializing countries. Results show that high rates of growth of manufacturing do not translate to high productivity rates in Singapore, Indonesia, Thailand, and Mauritius, but they do so in South Korea. A negative relation exists for Malaysia. This work questions the operation of Kaldor’s laws in the context of globalization and suggests a revision of the laws.
Mechanism of intracellular detection of glucose through nonenzymatic and boronic acid functionalized carbon dots

The objective of the research described here is to elucidate the fundamental mechanism by which the new class of "inert" non-enzymatic and boronic acid functionalized carbon dots-based sensors facilitate intracellular detection of glucose. The study suggests that the mechanism of detection of glucose involved selective assembly and fluorescence quenching of the carbon dots with excellent dynamic response to varying concentration of glucose within the biological range (1-100 mM). The strong dynamic response was related to high selectivity to biomolecules and inertness of carbon dots. Furthermore, the functionalization of carbon dots with boronic acid was the governing factor response for the passive character of the carbon dots. The study lays the foundation for the new field of carbon-based nanochemosensors.
Coho salmon escapement and trends in migration timing to a data-poor river: estimates from a Bayesian hierarchical model

Data to inform fisheries management are often limited in remote or low economic value fisheries. Here, we use a Bayesian hierarchical modeling structure and two alternative migration timing models to estimate the annual escapement of coho salmon (Oncorhynchus kisutch) to the Chignik River (Alaska, USA) in years with little data, borrowing information from data-rich years to inform parameter estimates. Additionally, we examined trends in peak migration timing between 1922 and 2013 and relative to environmental conditions. Our analyses show that annual escapement estimates are prone to substantial errors unless daily escapement is enumerated for at least 7 days after peak migration date. Finally, peak migration date was negatively correlated with the strength of the Pacific Decadal Oscillation in May–August, and increased over time, though the significance of these associations was dependent on the specific form of the migration timing model used. The modeling approach we present here is easily adaptable to...
Alliance A091103: A multicenter phase II study of the angiopoietin-1 and -2 peptibody trebananib (AMG386) for the treatment of angiosarcoma (AS).

10568 Background: AS is a rare, aggressive, malignant endothelial cell tumor constituting 1-2% of all soft tissue sarcomas with 35% 5-yr survival. Cytotoxic agents have demonstrated ~15% response r...
Research Note: The Utilization of Recycled Sheetrock (Refined Gypsum) as a Litter Material for Broiler Houses

Abstract A study was conducted to evaluate the utilization of refined gypsum (recycled sheetrock) as a litter material on the growth performance and mortality of broiler chicks grown to market age. Broilers were placed in pens with either 13 cm fir wood shavings, 13 cm refined gypsum, or 9 cm refined gypsum topped with 4 cm fir shavings, and grown to 41 days of age. Litter material had no significant influence on chick mortality, feed conversion, condemnations, and incidences of leg abnormalities. Body weight gain was significantly lower for chicks reared on refined gypsum compared with the other litter treatments at 21 days of age, but by Day 41 no differences were observed between litter treatments. Percentage litter moisture of refined gypsum was significantly lower than either wood shaving treatments at both 21 and 41 days, although on a weight basis, the gypsum contained equal or more water. Litter material had no influence on room or brooding temperatures. Although it is quite dusty initially when placed in the house, refined gypsum may be an alternative bedding material to be utilized as a base and top-dressed with wood shavings.
Zinc Oxide, Bulk Growth of

Zinc oxide is a wide bandgap semiconductor with potential applications as a transparent transistor and a light-emitting device in the blue-to-ultraviolet region. The high quality of both hydrothermal and vapor phase-grown ZnO crystals is indicated by distinct, sharp photoluminescence peaks. The crystal color of hydrothermal ZnO is nonuniform because of its anisotropic crystal growth habit in which the growth rate of each sector depends on orientation. Slices cut from the lighter region are semi-insulating, whereas those from the dark sector are n-type conducting. Improved polishing methods result in significantly improved surface quality as measured by the photoluminescence and rocking curve widths. When properly polished, hydrothermal ZnO exhibits optical properties similar to vapor phase-grown ZnO. Therefore, proper surface preparation is necessary to evaluate the quality of ZnO substrates.
A New Method of Calculating Inheritance Factors in Mixed Prior

The effect of multivariate population from history samples and field samples on reliability evaluation in the pass-fail cases was investigated.The rationality of the mixed prior distribution was analyzed.A new method of determining the inheritance factors in the mixed prior was presented by using Kullback information.Last,their results from different methods were compared and analyzed to prove its effectiveness.
Implementation and Effect Evaluation of Obstetric Neonatal Immunization Information Management System

Objective Evaluation of obstetric neonatal immunization information management system implementation and evaluate effect,strengthen and standardize child vaccination information management system reports,improve immunization information collection timely rates and accuracy and coverage.Method By using the Browser /Server( B /S) structure,to establish obstetric neonatal vaccination information management platform and to achieve the systematic management to Hubei province's 1457maternity units inoculated users and more than 500 units of health administrative departments and disease prevention and control,and obstetric neonatal vaccination case information management system. Based on the selected units,children's immunization information automatically sent to the 1844 vaccination units in the whole province. The client download the vaccination information,complete platform and customer end of data between dynamic updates. Result After implementation the information system for two years,there were total 1,457 units of obstetric inoculation in the province,the user system coverage was 100%.There were 1,392 obstetrics which being in charge of neonatal delivery,and the coverage of establishingfile of neonatal in obstetric was 95. 54%.1,271,781 neonatal completed the immunization information. Completeness of case immunization information was 94. 02%. Timely filing rate within5 days was 87. 19%,the timely audit rate within 5days was 95. 64%. Bacilli Calmette-Guerinvaccine vaccination rate was 86. 27%,HepB1coverage was 95. 58%,timely HepB1coverage was90. 26%,mothers' hepatitis B surface antigen positive rate was 4. 12%,all neonatal hepatitis B immuno globulin coverage rate was 5. 45%. Conclusion Implementation and application of neonatal vaccination information management system in obstetric enhanced information collection timeliness,accuracy and completeness. It resolved problems,such as getting correct targeted population,repeat vaccination cards,sharing immunization information of migrant children,and inaccuracy vaccination coverage.
The long-term safety of danazol in women with hereditary angioedema*

Although the short-term safety (less than or equal to 6 months) of danazol has been established in a variety of settings, no information exists as to its long-term safety. We therefore investigated the long-term safety of danazol by performing a retrospective chart review of 60 female patients with hereditary angioedema treated with danazol for a continuous period of 6 months or longer. The mean age of the patients was 35.2 years and the mean duration of therapy was 59.7 months. Virtually all patients experienced one or more adverse reactions. Menstrual abnormalities (79%), weight gain (60%), muscle cramps/myalgias (40%), and transaminase elevations (40%) were the most common adverse reactions. The drug was discontinued due to adverse reactions in 8 patients. No patient has died or suffered any apparent long-term sequelae that were directly attributable to the drug. We conclude that, despite a relatively high incidence of adverse reactions, danazol has proven to be remarkably safe over the long-term in this group of patients.
Impact of Postreconstitution Room Temperature Storage on the Efficacy of IncobotulinumtoxinA Treatment of Dynamic Lateral Canthus Lines.

BACKGROUND: The efficacy of botulinum neurotoxin type A after prolonged storage at room temperature is currently unknown. This randomized, double-blinded, split-face study investigated the impact of postreconstitution 25°C storage for 1 week on the clinical efficacy of incobotulinumtoxinA in the treatment of lateral canthus lines. PATIENTS AND METHODS: Twenty-one participants with at least mild to moderate crow's feet at maximum contraction on the Crow's Feet Grading Scale (CFGS) underwent injection to each lateral canthus area with 10 U of freshly reconstituted and room temperature-stored product and followed for 4 months. Responders were defined as those demonstrating at least a 1-point improvement on their CFGS score. RESULTS: At each visit (2 weeks and 1, 2, 3, and 4 months), there was no statistical difference in the rate of responders between the fresh and the stored products. In addition, the percentage of responders displaying a 2-point versus a 1-point improvement and response longevity did not statistically differ between both products for the entire 4-month study duration. CONCLUSION: Prolonged storage of incobotulinumtoxinA at room temperature does not appear to significantly alter its efficacy or longevity in the treatment of dynamic lateral canthus lines.
MiHub: Wearable Management for IoT

The availability of Internet of Things (IoT)-enabled devices has resulted in a rapid increase in the number of devices a user carries with them. To support the collection of data from the set of a user's devices as well as interact with the environment around them, we present MiHub, a system architecture that dynamically manages limited resources and redundant services based on the resource availability and the dynamically changing set of a user's personal devices.For any given set of co-located user devices, a MiHub is elected, which then configures the set of services on the devices in its proximity. To provide more reliable data access, MiHub is designed around the use of more expensive primary data sources, supported by low cost secondary services that can quickly take over upon failure of the primary source. We evaluate the basic components of MiHub, highlighting its energy-efficient mechanisms to ensure IoT-enabled service availability in the face of dynamically changing groups of devices in the proximity of the user
Phospho-BRD4: transcription plasticity and drug targeting

BRD4 is an epigenetic regulator and transcription cofactor whose phosphorylation by CK2 and dephosphorylation by PP2A modulates its function in chromatin targeting, factor recruitment, and cancer progression. While the bromodomains of BET family proteins, including BRD4, BRD2, BRD3 and BRDT, have been the primary targets of small compounds such as JQ1, I-BET and MS417 that show promising anticancer effects against some hematopoietic cancer and solid tumors, drug resistance upon prolonged treatment necessitates a better understanding of alternative pathways underlying not only the resistance but also persistent BET protein dependence for identifying new targets and effective combination therapy strategies.
Optimal Operations of a Batch Enzyme Reactor: Isomerization of D-Glucose to D-Fructose

Enzymatic isomerization of D-glucose results in a mixture containing both D-glucose and D-fructose, which is approximately equivalent in sweetness to an invert sugar obtained by hydrolyzing sucrose and which can be used successfully in place of sucrose in many applications such as in beverages and baked foods. With an abundant supply of corn starch hydrolyzates available at a reasonable price many major corn processing companies and sugar refineries have entered or are entering into the business of producing high fructose mixtures from these hydrolyzates (1). This represents one of the largest industrial applications of enzymes (2), an extensive review of which has been given by Hamilton et al (3).
Scan-associated distress in lung cancer: Quantifying the impact of “scanxiety”

Abstract Objectives Diagnostic imaging may be a major source of cancer-related distress, a condition known as “scanxiety”. Scant scholarly work has been performed to evaluate scan-associated distress in cancer. We sought to characterize risk factors for scan-associated distress among patients with Non-Small Cell Lung Cancer (NSCLC), and to evaluate the impact of scan-associated distress on quality of life. Materials and methods We conducted a cross-sectional survey study of patients with recurrent/metastatic NSCLC treated at an academic medical center. Clinical and demographic variables were obtained through chart abstraction and patient self-report. We used a modified version of the Impact of Event Scale 6 (IES-6) to specifically assess distress associated with scans, and quality of life was measured using the Functional Assessment of Cancer Therapy − Lung (FACT-L). Results Among 103 participants (survey response rate 76.3%), median age was 67, 61.2% were women, and 82.5% were white. At the study visit, 72.8% of subjects discussed a recent scan, and 83% reported some scan-associated distress. Scan-associated distress was not associated with whether the patient had a recent scan, progressive disease or time from diagnosis. Scan-associated distress was associated with impaired quality of life (p = 0.004); each unit increase in IES-6 corresponded to an approximately one-unit decrease in FACT-L score. Conclusion Scan-associated distress is a common problem among patients with NSCLC, and is associated with impaired quality of life. Scan-associated distress severity was not associated with time since diagnosis or whether a recent scan was discussed at the study visit, which implies scan-associated distress may be a persistent problem.
Heterogeneous effects of norepinephrine on spontaneous and stimulus-driven activity in the male accessory olfactory bulb

Norepinephrine (NE) release has been linked to experience-dependent plasticity in many model systems and brain regions. Among these is the rodent accessory olfactory system (AOS), which is crucial for detecting and processing socially relevant environmental cues. The accessory olfactory bulb (AOB), the first site of chemosensory information processing in the AOS, receives dense centrifugal innervation by noradrenergic fibers originating in the locus coeruleus. Although NE release has been linked to behavioral plasticity through its actions in the AOB, the impacts of noradrenergic modulation on AOB information processing have not been thoroughly studied. We made extracellular single-unit recordings of AOB principal neurons in ex vivo preparations of the early AOS taken from adult male mice. We analyzed the impacts of bath-applied NE (10 μM) on spontaneous and stimulus-driven activity. In the presence of NE, we observed overall suppression of stimulus-driven neuronal activity with limited impact on spontaneous activity. NE-associated response suppression in the AOB came in two forms: one that was strong and immediate (21%) and one other that involved gradual, stimulus-dependent monotonic response suppression (47%). NE-associated changes in spontaneous activity were more modest, with an overall increase in spontaneous spike frequency observed in 25% of neurons. Neurons with increased spontaneous activity demonstrated a net decrease in chemosensory discriminability. These results reveal that noradrenergic signaling in the AOB causes cell-specific changes in chemosensory tuning, even among similar projection neurons.NEW & NOTEWORTHY Norepinephrine (NE) is released throughout the brain in many behavioral contexts, but its impacts on information processing are not well understood. We studied the impact of NE on chemosensory tuning in the mouse accessory olfactory bulb (AOB). Electrophysiological recordings from AOB neurons in ex vivo preparations revealed that NE, on balance, inhibited mitral cell responses to chemosensory cues. However, NE's effects were heterogeneous, indicating that NE signaling reshapes AOB output in a cell- and stimulus-specific manner.
A Feasibility Study of an Approach to Extend Research Footprints

Funding agencies and the National Academies of Science, Engineering, and Medicine have been promoting the importance of interdisciplinary research (IDR). Supporting team-based IDR requires the ability to discover the expertise needed to solve complex problems. Many universities have adopted expertise systems, which includes the presentation of keywords or concepts to identify experts. The efforts at University of Texas at El Paso (UTEP) have focused on building “communities of practice” that support diverse faculty who have an affinity for a particular topic and facilitate the ability to identify researchers with diverse expertise, knowledge, and skills who can contribute to new initiatives on campus. Our premise is that the university can facilitate the identification of potential contributors to communities of practice by correlating their associated ontologies to the concepts associated with researchers’ publications and proposal submissions. This paper presents the results of a preliminary study to examine the feasibility of the approach.
Reducing Stress Among Mothers in Drug Treatment: A Description of a Mindfulness Based Parenting Intervention

Background Parenting women with substance use disorder could potentially benefit from interventions designed to decrease stress and improve overall psychosocial health. In this study we assessed whether a mindfulness based parenting (MBP) intervention could be successful in decreasing general and parenting stress in a population of women who are in treatment for substance use disorder and who have infants or young children. Methods MBP participants (N = 59) attended a two-hour session once a week for 12 weeks. Within-group differences on stress outcome measures administered prior to the beginning of the MBP intervention and following the intervention period were investigated using mixed-effects linear regression models accounting for correlations arising from the repeated-measures. Scales assessed for pre-post change included the Perceived Stress Scale-10 (PSS) and the Parenting Stress Index-Short Form (PSI). Results General stress, as measured by the PSS, decreased significantly from baseline to post-intervention. Women with the highest baseline general stress level experienced the greatest change in total stress score. A significant change also occurred across the Parental Distress PSI subscale. Conclusions Findings from this innovative interventional study suggest that the addition of MBP within treatment programs for parenting women with substance use disorder is an effective strategy for reducing stress within this at risk population.
Collision rate coefficient for charged dust grains in the presence of linear shear.

Like and oppositely charged particles or dust grains in linear shear flows are often driven to collide with one another by fluid and/or electrostatic forces, which can strongly influence particle-size distribution evolution. In gaseous media, collisions in shear are further complicated because particle inertia can influence differential motion. Expressions for the collision rate coefficient have not been developed previously which simultaneously account for the influences of linear shear, particle inertia, and electrostatic interactions. Here, we determine the collision rate coefficient accounting for the aforementioned effects by determining the collision area, i.e., the area of the plane perpendicular to the shear flow defining the relative initial locations of particles which will collide with one another. Integration of the particle flux over this area yields the collision rate. Collision rate calculations are parametrized as an enhancement factor, i.e., the ratio of the collision rate considering potential interactions and inertia to the traditional collision rate considering laminar shear only. For particles of constant surface charge density, the enhancement factor is found dependent only on the Stokes number (quantifying particle inertia), the electrostatic energy to shear energy ratio, and the ratio of colliding particle radii. Enhancement factors are determined for Stokes numbers in the 0--10 range and energy ratios up to 5. Calculations show that the influences of both electrostatic interactions and inertia are significant; for inertialess ($\mathrm{St}=0$) equal-sized and oppositely charged particles, we find that even at energy ratios as low as 0.2, enhancement factors are in excess of 2. For the same situation but like-charged particles, enhancement factors fall below 0.5. Increasing the Stokes number acts to mitigate the influence of electrostatic potentials for both like and oppositely charged particles; i.e., inertia reduces the enhancement factor for oppositely charged particles and increases it for like-charged particles. Uniquely, at elevated Stokes numbers with attractive potentials we find collisionless ``pockets'' within the collision area, which are regions completely bounded by the collision area but within which collisions do not occur. Regression equations to results are provided, enabling calculation of the enhancement factor as a function of energy ratio and Stokes number. In total, this study both leads to insight into the collision dynamics of finite-inertia, charged particles in shear flows, and provides a means to simply calculate the particle-particle collision rate coefficient.
Fully Automatic, Real-Time Vehicle Tracking for Surveillance Video

We present an object tracking framework which fuses multiple unstable video-based methods and supports automatic tracker initialization and termination. To evaluate our system, we collected a large dataset of hand-annotated 5-minute traffic surveillance videos, which we are releasing to the community. To the best of our knowledge, this is the first publicly available dataset of such long videos, providing a diverse range of real-world object variation, scale change, interaction, different resolutions and illumination conditions. In our comprehensive evaluation using this dataset, we show that our automatic object tracking system often outperforms state-of-the-art trackers, even when these are provided with proper manual initialization. We also demonstrate tracking throughput improvements of 5× or more vs. the competition.
Weighted kernel deterministic annealing: A maximum-entropy principle approach for shape clustering

Kernel k-means and spectral clustering methods have both been used extensively to cluster data that are non-linearly separable in input space. While there has been significant research since their inceptions, both the methods have some drawbacks. Similar to the basic k-means algorithm, the Kernel k-means algorithm is sensitive to initialization. On the other hand, the spectral methods are based on finding eigenvectors and can be computationally prohibitive. In this paper, we propose a novel maximum-entropy principle (MEP) based weighted-kernel deterministic annealing (WKDA) algorithm, which is independent of initialization and has ability to avoid poor local minima. Additionally, we show that the WKDA approach reduces to Kernel k-means approach as a special case. Finally, we extend the proposed algorithm to include constrained-clustering and present the results for a variety of interesting data sets.
BP Measurement Techniques What They Mean for Patients with Kidney Disease

Patients with CKD typically have hypertension. Manual BP measurement in the office setting was used to define hypertension, establish eligibility, and assess BP targets in the epidemiologic studies and early randomized, controlled trials that inform current management of hypertension. Use of automated oscillometric devices has largely replaced manual BP measurement in the office and clinical trials. These newer devices may reduce the white coat effect and facilitate guideline-adherent measurement protocols. Obtaining BP measurements outside of the office with home and ambulatory BP monitoring is now more common. Out of office BPs are especially important in patients with CKD, because reduced GFR and proteinuria are associated with masked hypertension (normal office BP and elevated BP outside of the office), elevated nighttime BP, and abnormal diurnal variation in BP, all of which are associated with higher risk for target organ damage and adverse outcomes. Also, it is now feasible to routinely measure central BP and central hemodynamics. These measures are of greater importance to patients with CKD given the higher prevalence of increased sympathetic tone, arteriosclerosis, and inflammation as well as impaired sodium excretion and endothelial dysfunction, which lead to alterations in central BPs in this population. In this review, we describe various BP measurement techniques and how they apply to the care of patients with CKD.
Mood vs. Interpersonal Affect: Identifying Process and Rating Distortions in Performance Appraisal

This study was designed to simultaneously analyze the influence of mood and interpersonal affect on the performance appraisal process. Results suggest that affect consistency, as opposed to mood consistency, is likely to influence the weighting of recalled performance information and ratings subsequently assigned. Surprisingly, a mood-incongruent effect also occurred when weighting the performance information. Aside from affective influences, the raters assigned the most weight to positive performance incidents, however, the raters remembered more of the negative performance. Implications for appraisal practice and directions for future research are discussed.
Inference Progress in Missing Data Analysis from Independent to Longitudinal Setup

In the independent setup with multivariate responses, the data become incomplete when partial responses, such as responses on some variables as opposed to all variables, are available from some individuals. The main challenge here is obtaining valid inferences such as unbiased and consistent estimates of mean parameters of all response variables by using available responses. Typically, unbalanced correlation matrices are formed and moments or likelihood analysis based on the available responses are employed for such inferences. Various imputation techniques also have been used. In the longitudinal setup, when a univariate response is repeatedly collected from an individual, these repeated responses become correlated and the responses form a multivariate distribution. In this setup, it may happen that a portion of responses are not available from some individuals under study. These non-responses may be monotonic or intermittent. Also the response may be missing following a mechanism such as missing completely at random (MCAR), missing at random (MAR), or missing non-ignorably. In a longitudinal regression setup, the covariates may also be missing, but typically they are known for all time periods. Obtaining unbiased and consistent regression estimates specially when longitudinal responses are missing following MAR or ignorable mechanism becomes a challenge. This happens because one requires to accommodate both longitudinal correlations and missing mechanism to develop a proper inference tool. Over the last three decades some progress has been made toward this mainly by taking partial care of missing mechanism in developing estimation techniques. But overall, they fall short and may still produce biased and hence inconsistent estimates. The purpose of this paper is to outline these perspectives in a comprehensive manner so that real progress and challenges are understood in order to develop proper inference techniques.
Real-time cine first-pass perfusion imaging enables rapid detection of functionally significant high-grade coronary stenosis

Background Among the spectrum of patients with coronary artery disease (CAD), those suffering from high-grade stenosis are at a significantly elevated risk for adverse events [1]. Such high-grade disease may result in the so-called “coronary steal” phenomenon under vasodilator stress [2] thereby inducing wall-motion abnormalities (WMAs) in the affected territories, referred to as transient ischemic dilation. We developed a “real time” cine first-pass perfusion (FPP) CMR method for concurrent imaging of myocardial function and perfusion. We hypothesized that this method is capable of simultaneously capturing stress-induced perfusion defects and WMAs in a single ungated scan. Methods
Analysis of Acid Deposition Due to Sulfur Dioxide Emissions from Ohio

Atmospheric transport of emissions over hundreds of kilometers is termed long range transport. Examples of this phenomenon are: the continental advection of smoke generated by volcanos and forest fires, high tropospheric levels of ozone in regions where the precursors of ozone production are not found in high quantities, radioactive fallout in regions distant from the nuclear release, and the transport and deposition of sulfur and nitrous oxides from industrial sources on areas hundreds of kilometers away.
tRNA-dependent translational control of in vitro hemoglobin synthesis

Abstract A tRNA-dependent rabbit reticulocyte cell-free system has been developed which is highly active in synthesizing hemoglobin. When unfractionated tRNA is used to supplement the system, approximately equal amounts of α and β chains are produced. When tRNA fractionated by Freon reverse phase chromatography is utilized, but with a specific portion deleted, α chain production is reduced to approximately 67% of the production of β chains.
Trafficking of TRP Channels: Determinants of Channel Function

Transient receptor potential (TRP) channels are members of a relatively newly described family of cation channels that display a wide range of properties and mechanisms of activation. The exact physiological function and regulation of most of these channels have not yet been conclusively determined. Studies over the past decade have revealed important features of the channels that contribute to their function. These include homomeric interactions between TRP monomers, selective heteromeric interactions within members of the same subfamily, interactions of TRPs with accessory proteins and assembly into macromolecular signaling complexes, and regulation within functionally distinct cellular microdomains. Further, distinct constitutive and regulated vesicular trafficking mechanisms have a critical role not only in controlling the surface expression of TRP channels but also their activation in response to stimuli. A number of cellular components such as cytoskeletal and scaffolding proteins also contribute to TRP channel trafficking. Thus, mechanisms involved in the assembly and trafficking of TRP channels control their plasma membrane expression and critically impact their function and regulation.
Eratosthenes: Significant Digits and Interval Arithmetic

Eratosthenes of Cyrene was a Greek mathematician who lived during the latter part of the third century B.C. He is best known for discovering an algorithm, called the Sieve of Eratosthenes, for enumerating prime numbers. We, however, are interested in him for another reason. In about 225 B.C., more than 17 centuries before Columbus, he determined the circumference of the earth.
Macromolecular Drug Delivery

Advances in molecular biotechnology coupled with novel technologies such as combinatorial chemistry and high-throughput screening have led to the discovery of a large number of drugs with macromolecular properties. Macromolecular therapeutics encompasses a variety of approaches including recombinant proteins, genes, antisense, and small interfering RNAs, all of which have larger molecular dimensions than conventional drugs. These macromolecules have emerged as a powerful class of drugs for a wide range of therapeutic indications mainly on the basis of their site-specific activity and reduced side effects. However, these drugs present an enormous challenge for noninvasive delivery as they are poorly absorbed and rapidly metabolized in the body. To surmount these obstacles, either the other aspects of the drug may be exploited or novel delivery systems may be developed. Cost-effectiveness suggests that developing an improved delivery system for an existing drug is a better alternative than modifying the chemical structure of the drug or discovering new drug entities. This chapter focuses on macromolecular drugs and their delivery systems including liposomes, polymers, peptides, and nanoparticles.
A dormant TIL phenotype defines non-small cell lung carcinomas sensitive to immune checkpoint blockers

The biological determinants of sensitivity and resistance to immune checkpoint blockers are not completely understood. To elucidate the role of intratumoral T-cells and their association with the tumor genomic landscape, we perform paired whole exome DNA sequencing and multiplexed quantitative immunofluorescence (QIF) in pre-treatment samples from non-small cell lung carcinoma (NSCLC) patients treated with PD-1 axis blockers. QIF is used to simultaneously measure the level of CD3+ tumor infiltrating lymphocytes (TILs), in situ T-cell proliferation (Ki-67 in CD3) and effector capacity (Granzyme-B in CD3). Elevated mutational load, candidate class-I neoantigens or intratumoral CD3 signal are significantly associated with favorable response to therapy. Additionally, a “dormant” TIL signature is associated with survival benefit in patients treated with immune checkpoint blockers characterized by elevated TILs with low activation and proliferation. We further demonstrate that dormant TILs can be reinvigorated upon PD-1 blockade in a patient-derived xenograft model.
DeMiLTE: Detecting and Mitigating LTE Interference for Enterprise Wi-Fi in 5 GHz

LTE in unlicensed 5 GHz bands is being deployed by mobile operators for increased capacity. In this paper, we conduct an extensive measurement study with commodity LTE and Wi-Fi hardware to identify key coexistence challenges. Our study -- the first to include a commercial LAA base station -- confirms that LTE interference causes WiFi performance to degrade, harming 802.11ac high-throughput features. We then present DeMiLTE -- a system for commodity enterprise WiFi APs that detects, quantifies, and reacts to LTE interference. To our best knowledge, our solution is the first that achieves fair coexistence without modifying the LTE PHY/MAC, while still being fully-compliant to the 802.11ac standard. DeMiLTE's architecture is based on lightweight per-link interference detection and enables WiFi APs to mitigate LTE-induced performance degradation with minimal overhead. Our evaluation results show that DeMiLTE can provide up to 110% throughput gains and alleviate client disruption caused by LTE interference.
Reproductive decisions as mediators between education and employment of women in Kyrgyzstan.

Researchers created a large body of evidence showing that education and fertility are strong determinants of women's employment. In postsocialist economies, women's reproductive decisions have become more critical to employment opportunities. Yet the issue is not well-understood. The researchers focus on the mediating roles of reproductive decisions on the relationship between education and employment among Kyrgyzstani women. The study data come from the 2012 Demographic and Health Survey (N = 2419). Consistent with other research, more education was associated with fewer number of children and being employed. An unexpected finding was that having more children was associated with increased employment.