cssi/SciSciGPT-SciSciNet huggingface dataset:
The effect of power (US intensity x US duration) on shuttlebox avoidance acquisition in goldfish

A factorial arrangement of four shock intensity levels (7.5, 10, 15, or 20 V ac) by three shock durations (100, 200, or 400 msec), and NO US control was used to examine the effect of power (shock intensity x shock duration) on CAR shuttlebox acquisition in goldfish (Carassius auratus). On CAR performance, increasing power level at first increased then decreased avoidance acquisition indicating an inverted “U” function. On total activity, shuttle rates by NO US controls were high. Low levels of power produced a substantial decrease in total activity. Increasing power yielded first an increase then decrease in shuttle rates. Thus, an inverted “U” function between total activity and power, excluding the control level, is also evident. The initial effect of low power levels is to depress total activity.
Recurrent venous thromboembolism in glioblastoma.

Abstract Background Patients with glioblastoma (GBM) are at increased risk of initial and recurrent venous thromboembolism (VTE) but rates of recurrence and real-world treatment choices are incompletely understood. Objectives We aim to describe the treatment of incident VTE, report incidence and risk factors for recurrence. Patients/methods We conducted a retrospective cohort study of consecutive Cleveland Clinic patients with GBM presenting with objectively diagnosed deep vein thrombosis (DVT) or pulmonary embolism (PE) from 2007 to 2013 with at least 6-month follow-up. We collected information on patient demographics, VTE incidence, treatment and recurrence. Data were analyzed using multivariate logistic regression analysis. Results Of 450 patients with GBM, 145 (32.2%) developed VTE and comprised the study population. Of these, 11 (7.6%) experienced PE, 117 (80.7%) had DVT and 16 (11%) had DVT as well as PE. Fifty five (37.9%) VTE events occurred in the first 30 post-operative days and 56 (38.6%) during chemotherapy. Thirty one (21.4%) patients were untreated. Treatments included enoxaparin (N = 36, 24.8%), warfarin (15, 10.3%) or vena cava filters either alone (N = 39, 26.9%) or in combination with anticoagulation (N = 21, 14.5%). Recurrent VTE occurred in 39 patients (26.9%).In multivariate analysis, lack of long term anticoagulation (HR 11.2, CI 1.5–86.3, p Conclusion VTE and recurrent VTE are highly prevalent throughout the disease course among patients with GBM. Long term anticoagulation is associated with reduced risk of recurrent VTE but is often not utilized.
Microanalysis with HIM

For many users, the most important application of an SEM is its ability to identify the chemical composition of a specimen. Energy dispersive spectroscopy (EDS) of the X-rays fluoresced from samples of interest by the incident electron beam provides chemical microanalysis combining unparalleled sensitivity together with high spatial resolution for elements across the entire periodic table. This technique would therefore also be the automatic first choice for microanalysis when using ion beams if it were a viable option.
The Emergence and Development of the Power of International Courts to Determine Their Jurisdiction

Presenting the first “Draft Convention on Arbitral Procedure” to the General Assembly of the United Nations in 1952, the International Law Commission stated that Article n of that draft “lays down a general principle [and] calls for no comment.”1 This Article provided that: “The Tribunal, as the judge [Fr. maitre] of its own competence, possesses the widest powers to interpret the compromis.” Following developments proved, however, this short remark of the Commission to be mistaken. Commentators in the Sixth Committee of the General Assembly contended that this Article, in its French wording, included a “serious innovation,”2 and claimed that it diverged from the actual practice.3 Later on, when the Commission replaced its Draft Convention by a Model Draft, it substituted Article 9 for the objectionable Article 11 after a modification that removed from its French version the phrase “maitre de sa competence” (making it only “juge de sa competence”), and excluded the word “widest” as a description of the tribunal’s powers to interpret the compromise.4
Harnessing University Entrepreneurship for Economic Growth: Factors of Success Among University Spin-offs

University spin-offs are an important vehicle for knowledge dissemination and have the potential to generate jobs and economic growth. Despite their importance, little research exists on spin-off performance or impact, especially from the perspective of academic entrepreneurs. Using logit regression, this article makes a scholarly contribution by testing the relationship between spin-off success—defined here as technology commercialization—and multiple factors derived from the extant literature. Several significant variables are found to enable commercialization success within the sample, including venture capital, multiple and external licenses, outside management, joint ventures with other companies, previous faculty consulting experience, and—surprisingly—a negative relationship to post-spin-off services provided by universities. The results have important implications for public policy and management, supporting an overall “open innovation” approach to spin-off success.
Respirable Crystalline Silica Exposures During Asphalt Pavement Milling at Eleven Highway Construction Sites

ABSTRACTAsphalt pavement milling machines use a rotating cutter drum to remove the deteriorated road surface for recycling. The removal of the road surface has the potential to release respirable crystalline silica, to which workers can be exposed. This article describes an evaluation of respirable crystalline silica exposures to the operator and ground worker from two different half-lane and larger asphalt pavement milling machines that had ventilation dust controls and water-sprays designed and installed by the manufacturers.Manufacturer A completed milling for 11 days at 4 highway construction sites in Wisconsin, and Manufacturer B completed milling for 10 days at 7 highway construction sites in Indiana. To evaluate the dust controls, full-shift personal breathing zone air samples were collected from an operator and ground worker during the course of normal employee work activities of asphalt pavement milling at 11 different sites.Forty-two personal breathing zone air samples were collected over 21 day...
Alcohol Consumption and Tobacco Use Among Residents in Qidong County

Objective To investigate the behaviors of alcohol drinking and tobacco use in the residents of Qidong County,and to provide the evidence for adopting further intervention measures. Methods Residents aged over 18 years in 6 urban-communities and 18 villages were selected by stratified cluster random sampling and a household survey was conducted using questionnaire interview. Results A total of 3,756 residents,including 1,877 men and 1,879 women,were surveyed,among them 1,416 individuals came from urban areas and 2,340 from rural areas.The total smoking rate was 30.6%,and the drinking rate was 17.3%.The rates of drinking and smoking were correlated with region,sex,age,occupation,education background,and marital status(P0.05 or P0.01).The smoking rate in urban areas was lower than that in rural areas,while the drinking rate in urban areas was higher than that in rural areas.The rates of drinking and smoking in males were both higher than those of females.The occupational characteristics showed that the rates of drinking and smoking were the highest among the cadres.The drinking rate was higher in high-income group than that in other groups(P0.01),but the smoking rate was not related to income.There was a significant correlation both between duration of smoking and smoking dosage per day,and duration of drinking and drinking dosage per day(Both R=0.872,P0.01).Smoking behavior was correlated with drinking behavior(R=0.52,P0.01). Conclusions The rates of smoking and drinking are both pretty high in Qidong County.The results suggest that it is necessary to develop health education in the community residents for controlling and preventing alcohol and tobacco-related diseases.
Design of a Low Voltage and Great Current Switching Mode Power Supply

In this paper,based on the technology of active-clamp and synchronous rectification,a design of a low voltage and great current switching mode power supply is introduced.Then the characteristics of the main circuit and device selection are analyzed.Finally,the experiment result shows that the design is feasible.
Manned Lunar Vehicle Design

This paper describes the design of a possible manned lunar vehicle and some of the significant trade-offs in its design. To be discussed are propulsion trade-offs, protection against radiation, structural design tradeoffs, and other factors. The design is presented in detail and includes all elements of a manned lunar spacecraft. This includes emergency escape means for powered and outbound flight, space cabin design in cluding crew support, displays, controls and the like. Integration of propulsion, power, communications and other subsystems into the total manned lunar spacecraft will be summarized. A full scale detail mockuphas beenbuilt and is shown as part of this paper. This is the command/ re-entry vehicle for the lunar space craft and its internal features.
Virtual Sensors and Their Automotive Applications

We highlight potential of advanced signal processing algorithms for automotive problems of sensing various hard-to-measure quantities. We illustrate virtual sensor capabilities with three examples (misfire detection, torque monitor and sensorless detection of changes in tire pressure).
Organic metal challenges superconductor paradigm

According to the textbooks, superconductivity is destroyed in high magnetic fields. Even trace quantities of magnetic ions can lower the temperature at which a material loses its resistance to an electric current. So a few eyebrows were raised recently when a team of Japanese physicists found a material that becomes superconducting in a high magnetic field. Moreover, the material in question – an organic crystalline solid called λ-(BETS)2FeCl4 – contains a large concentration of magnetic ions (S Uji et al. 2001 Nature 410 908
Denitrifier community response to seven years of ground cover and nutrient management in an organic fruit tree orchard soil

Abstract Mechanisms through which microorganisms are impacted by surface application of ground cover and nutrient source in organic orchard management are not fully understood. Twelve ground cover (compost, wood chips, paper mulch, or mow-and-blow) by fertilizer (poultry litter, organic commercial, or a no-fertilizer control) treatment combinations were applied annually in April beginning in 2006, with soil collected in March 2007 and 2013 to determine the 1-year and 7-year effects of treatments on soil chemical and biological properties. Organic matter (OM) increased through time regardless of ground cover treatment averaged across fertilizers, with the greatest increase occurring with compost addition. Soil water content, microbial biomass N, ammonium-N, and nitrate-N were greater in 2013 than in 2007 at the 0–10 cm depth. Denaturing gradient gel electrophoresis analysis of denitrifying (nirK) communities revealed that fertilizers did not have a significant main effect or interaction with ground covers. Greater nirK richness and diversity coincided with clustering of the nirK community composition within compost treatments, and greater dissolved organic carbon concentrations with compost compared to wood chip or mow-and-blow treatments in 2007. By 2013 nirK communities in wood chip and compost ground covers tended to cluster together. Furthermore, soil nirK richness increased significantly from 2007 to 2013 in compost and wood chip treatments and was greatest in 2013 under those two ground covers. Diversity with wood chip addition increased from among the least in 2007 to among the greatest in 2013. Greater richness and diversity and community composition in the nirK community within a year of compost additions and gradually over time with wood chip addition indicate potential for enhanced denitrification in low OM, organic apple orchard soil receiving compost and wood chips mulches.
Resonant absorption in nanometer gold spherical particles

Resonance effects can occur upon laser absorption by micro and nanoparticles when a train of pulses is used. The pressure generated by the train of pulses may be significantly different than the pressure generated by a single pulse with the same total energy. For pulsed lasers with a gap duration between pulses that is an integer multiple of the characteristic oscillation time of the absorber, constructive interference occurs and the pressure is increased. For pulsed lasers with a gap duration between pulses that is an half integer multiple of the characteristic oscillation time of the absorber, destructive interference occurs and the pressure is significantly decreased. We present numerical computations showing the manifestation of this effect in gold particles with a radius of 100 nm. The resonance effects have implications for damage thresholds and therapeutic applications of laser radiation.
Ethnic Groups Across National Boundaries in Mainland Southeast Asia, Gehan Wijeyewardene, editor. Singapore: Institute of Southeast Asian Studies, 1990

Ethnic Groups Across National Boundaries in Mainland Southeast Asia. Gehan Wijeyewardene, editor. Singapore: Institute of Southeast Asian Studies, 1990. viii, 192 pp. Reviewed by Brian L. Foster , Dean, School of Arts and Sciences, University of Nebraska.
The Politics of Commiseration: On the Communicative Labors of “Co-Mothering” in El Alto

In El Alto, Bolivia, the communicative and affective capacities of local neighborhood women are often valorized as strategic sites for circulating governmental discourses across ethnolinguistic boundaries. Nowhere is this more evident than in the domain of public health. As this article explores, municipal health projects in El Alto increasingly cast neighborhood women in para-governmental roles, hoping to tap into the networks of community-based belonging they create and maintain through their everyday communicative labors. By focusing on the work performed by an often-overlooked genre of gendered discourse—comadreando, or “co-mothering” speech—this article calls attention to the concrete semiotic forms that mediate this kind of local governmentality. As I argue, everyday events of comadreando enact rituals of commiseration that build mutual trust and sympathy (confianza) between women and the households they head. But when figured in public health projects, they become vehicles of a broader politics of commiseration, one that aims to forge reliable channels of trust, goodwill, and sympathetic understanding between neighborhood actors and the state. However, as I also argue, the mobilization of such forms can open up such governmental strategies to unanticipated reappropriations, as the affective and communicative labors of women are diverted to more ambiguous ends.
Mechanism of Kin-Discriminatory Demarcation Line Formation between Colonies of Swarming Bacteria

Abstract Swarming bacteria use kin discrimination to preferentially associate with their clonemates for certain cooperative behaviors. Kin discrimination can manifest as an apparent demarcation line (a region lacking cells or with much lower cell density) between antagonist strains swarming toward each other. In contrast, two identical strains merge with no demarcation. Experimental studies suggest contact-dependent killing between different strains as a mechanism of kin discrimination, but it is not clear whether this killing is sufficient to explain the observed patterns. Here, we investigate the formation of demarcation line with a mathematical model. First, using data from competition experiments between kin discriminating strains of Myxococcus xanthus and Proteus mirabilis , we found the rates of killing between the strains to be highly asymmetric, i.e., one strain kills another at a much higher rate. Then, to investigate how such asymmetric interactions can lead to a stable demarcation line, we construct reaction-diffusion models for colony expansion of kin-discriminatory strains. Our results demonstrate that a stable demarcation line can form when both cell movement and cell growth cease at low nutrient levels. Further, our study suggests that, depending on the initial separation between the inoculated colonies, the demarcation line may move transiently before stabilizing. We validated these model predictions by observing dynamics of merger between two M. xanthus strains, where one strain expresses a toxin protein that kills a second strain lacking the corresponding antitoxin. Our study therefore provides a theoretical understanding of demarcation line formation between kin-discriminatory populations, and can be used for analyzing and designing future experiments.
Plasmono-magnetic material for precise photothermal heating

Noble metal nanoparticles have been extensively studied as photo-sensitive agents for photothermal cancer therapy. Precise control over the size and shape of the nanoparticles allowed strong optical absorption and efficient heat generation necessary for destroying a tumor to be achieved. However, one of the fundamental challenges of application of the nanoparticles towards photothermal cancer therapy is low specificity in the targeting tumor tissue in comparison with the healthy tissue and the resulting unfavorable biodistribution of the nanoparticles. Additional levels of control over particle distribution can be achieved by making the particles magnetic and using external magnets to control their accumulation in a tumor. Since the direct synthesis of particles with a magnetic core and a metallic shell limits the options for design and fine-tuning of plasmonic properties, the alternative approaches to the design of such materials have to be investigated. Here we propose and demonstrate a new design of a hybrid plasmono-magnetic material for photothermal heating created by grafting Au nanocages onto a surface of magnetic micro-beads. Next, we confirm its dual functionality in in vitro studies and show that individual hybrid particles can be magnetically controlled with a precision of a few micrometers and precisely destroy individual cells using plasmonic heating.
Nuclear Magnetic Resonance-Based Structural Characterization and Backbone Dynamics of Recombinant Bee Venom Melittin.

In recent years, there has been a resurgence of interest in melittin and its variants as their therapeutic potential has become increasingly evident. Melittin is a 26-residue peptide and a toxic component of honey bee venom. The versatility of melittin in interacting with various biological substrates, such as membranes, glycosaminoglycans, and a variety of proteins, has inspired a slew of studies that aim to improve our understanding of the structural basis of such interactions. However, these studies have largely focused on melittin solutions at high concentrations (>1 mM), even though melittin is generally effective at lower (micromolar) concentrations. Here we present high-resolution nuclear magnetic resonance studies in the lower-concentration regime using a novel method to produce isotope-labeled (15N and 13C) recombinant melittin. We provide residue-specific structural characterization of melittin in dilute aqueous solution and in 2,2,2-trifluoroethanol/water mixtures, which mimic melittin structur...
New Inversions, the 'Joe Frazier Left Hook,' the IRS Notice, and Pfizer

This article discusses the “New Inversions” many U.S. firms are engaging in, as illustrated by the acquisition by a newly formed Irish holding company of the stock of (1) Endo, a U.S. firm and the real acquirer, and (2) Paladin, a Canadian firm and the real target. The article shows how these transactions are rendering a “Joe Frazier Left Hook” to the Treasury’s “Killer B” regulations even after the issuance by the IRS of Notice 2014-32 on April 25, 2014. The article then explores how “Ali” (a.k.a. Treasury) and the Congress can punch back against these transactions.
Introduction to Physical Properties and Elasticity Models

Estimating the in situ methane hydrate volume from seismic surveys requires knowledge of the rock physics relations between wave speeds and elastic moduli in hydrate/sediment mixtures. The elastic moduli of hydrate/sediment mixtures depend on the elastic properties of the individual sedimentary particles and the manner in which they are arranged. In this chapter, we present some rock physics data currently available from literature. The unreferenced values in Table I were not measured directly, but were derived from other values in Tables I and II using standard relationships between elastic properties for homogeneous, isotropic material. These derivations allow us to extend the list of physical property estimates, but at the expense of introducing uncertainties due to combining property values measured under different physical conditions. This is most apparent in the case of structure II (sII) hydrate for which very few physical properties have been measured under identical conditions.
"Getting From Here to There"-Mechanisms and Limitations to the Activation of the Androgen Receptor in Castration-Resistant Prostate Cancer

Despite the clinical regression that typifies the initial response of advanced prostate cancer to gonadal testosterone depletion, tumors eventually progress. However, evidence supports the concept that signaling via the androgen receptor (AR) is important in progression to castration-resistant prostate cancer (CRPC). Steroid hormones are synthesized from cholesterol in a series of tightly regulated steps involving the cleavage of carbon-carbon bonds, the introduction of functional groups derived from activated molecular oxygen, and the oxidation and reduction of carbon-carbon and carbon-oxygen bonds. In the adrenal cortex and gonads, steroidogenesis is tightly regulated, very efficient, and highly directional. In contrast, steroid metabolism in peripheral tissues is characterized by competing enzymes and pathways, low efficiency, and great variability. Many steps are mechanistically and functionally irreversible, but some are not, and the repertoire of specific enzymes, intracellular redox state, and access to hormone precursors all contribute to steroid flux and accumulation. The investigation of steroid metabolizing enzymes in CRPC often assumes that the pathways and the patterns of metabolism mirror those defined in the adrenals and the gonads and validated by human deficiency syndromes. Unfortunately, several potential pathways using different enzymes might contribute substantially to androgen synthesis in CRPC. Finally, a number of mechanisms have been reported by which the AR is activated independent of ligand. Recent observations have suggested that AR forms with constitutive activity occur in CRPC, stimulating transcription without a requirement for ligand. This overview outlines a broad view of how the mechanisms by which the AR may be activated, whether by alternate pathways of androgen synthesis or the production of alternate forms of the AR, with an emphasis on what aspects must be accounted for when using model systems to explore the biology of human prostate cancer.
Kinetic Profile of Chicken Macrophage Immune Response upon exposure to Salmonella-derived Endotoxin

Large scale gene expression studies expedite the discovery process and provide a comprehensive view of host immune response. We used the Affymetrix GeneChip chicken genome array to determine the nature and breadth of the gene activation elicited by endotoxin from Salmonella typhimirium (ST) 798. The data obtained from this type of research are important to improve vaccine development efficacy and to enhance animal health and food safety. Our findings may contribute to elucidation of disease response pathways.
The Hospital of the Future: Evidence-Based, Data-Driven

The hospitals of the future will have command centers that will assist decision-makers with real-time electronic clinical support system and tools similar to today’s airport’s air traffic control systems, another major data-driven corporation. Digital data are the foundation of such centers, and many hospitals have already adapted these digital technologies. In 2016 the national health expenditures were estimated at $3.4 trillion with a projected increase from 17.8% to 19.9% of the GDP between 2015 and 2025. The estimate of the artificial intelligence market is poised to reach $6.6 billion by 2021 and by 2026 will annually save the US healthcare $150 billion.
Differentially expressed gene networks, biomarkers, long noncoding RNAs, and shared responses with cocaine identified in the midbrains of human opioid abusers

Opioid abuse is now the most common cause of accidental death in the US. Although opioids and most other drugs of abuse acutely increase signaling mediated by midbrain dopamine (DA)-synthesizing neurons, little is known about long-lasting changes in DA cells that may contribute to continued opioid abuse, craving, and relapse. A better understanding of the molecular and cellular bases of opioid abuse could lead to advancements in therapeutics. This study comprises, to our knowledge, the first unbiased examination of genome-wide changes in midbrain gene expression associated with human opioid abuse. Our analyses identified differentially expressed genes and distinct gene networks associated with opioid abuse, specific genes with predictive capability for subject assignment to the opioid abuse cohort, and genes most similarly affected in chronic opioid and cocaine abusers. We also identified differentially expressed long noncoding RNAs capable of regulating known drug-responsive protein-coding genes. Opioid-regulated genes identified in this study warrant further investigation as potential biomarkers and/or therapeutic targets for human substance abuse.
Multiscale Dynamics of Small, Attractive Nanoparticles and Entangled Polymers in Polymer Nanocomposites

Polymer segmental dynamics, center-of-mass chain diffusion, and nanoparticle (NP) diffusion are directly measured in a series of polymer nanocomposites (PNC) composed of very small (radius ≈ 0.9 nm...
CONFESS: A humanistic, diagnostic-prescriptive computer program to decrease person-to-person interaction time during confession

Recent Vatican interest in the effect upon laymen of the shortage of professional priests (PP) and the decreased seminary enrollment of potential priests (P'P) has led to the development of Computerized Operations (Nonretrievable) for Expediting Sinner Services (CONFESS). This program provides a viable alternative to traditional confession procedures by listing penance requirements (by sin) on a private printout to confessees appropriate to the sin committed. This eliminates one problem which frequently occurs where the confessee, because he is under extreme duress, may forget the original penance. In addition, the program provides a probability estimate of the consequence of not completing the penance associated with the given sin; for example, number of years in purgatory. Thus, full freedom of choice is given to the participant/user (PU). The program requires no PP in-
P662 Does ultrasound measured renal length and volume discrepancy predict differential function on DMSA scanning

Investigation of children with urinary tract infection (UTI) or other renal disease ofteninvolvesa combination of dimercaptosuccinic acid (DMSA) imaging and ultrasound (US) imaging to identify structural and functional defects. DMSA imaging provides information on the relative function of the right and left kidneys and is considered the gold-standard imaging modality for the detection of renal scarring. DMSA imaging requires anintravenous injection of a radioactive agent and often requires sedationin babies and young children. DMSA imaging takes more than two hours to complete and is not suitable for frequent repeat studies. US imaging provides information on renal size, parenchymal appearance and structural abnormalities such as calyceal and/or renal pelvic dilatation. US imaging is non-invasive, does not involve ionising radiation and can be performed in most children without sedation or anaesthetic. US imaging takes less than 30 minutes to complete and can be repeated easily for follow up. We have obtained ethical approval to investigate the associations between DMSA-assessed renal function discrepancy with US assessment of renal length, renal volume, renal length discrepancy and renal volume discrepancy. Image data will be captured and analysed from children who underwent both DMSA imaging and renal US imaging in our hospital between 2015 and 2018. The analytical group (n=200) has been limited to those who underwent imaging as part of investigation of UTI or other renal disease who had DMSA and ultrasound scanning within six months of each other and whose images are adequate to obtain the relevant measurements. Finding strong associations and sufficient diagnostic accuracy may mean that the non-invasive and more easily performed US examination, which does not involve ionising radiation, may reduce the need for DMSA scanning in some children.
Climate Change, the Intersectional Imperative, and the Opportunity of the Green New Deal

ABSTRACTThis article discusses why climate change communicators, including scholars and practitioners, must acknowledge and understand climate change as a product of social and economic inequities....
Experimental Verification of 3D Metal Printed Dual Circular-Polarized Horn Antenna at V-Band

In this paper, a 3D metal printed dual circular-polarized horn antenna operating in the V-band is proposed, built and tested. This antenna consists of a horn and a circular waveguide, a single groove polarizer and is side-fed by orthogonally placed rectangular waveguide ports. The groove is placed at 45° with respect to the input ports and provides a phase delay of 90° to generate right- or left-hand circular polarization (RHCP or LHCP). The proposed antenna provides symmetric patterns for all planes and exhibits polarization isolation of more than 30 dB at broadside. This antenna is analyzed to realize wide impedance matching bandwidth and wide 3dB axial ratio (AR) bandwidth. A prototype of the horn antenna has been fabricated using 3D metal printing technology. Metal material with finite surface roughness is considered when modeling this antenna.
Hermite-Hadamard Type Inequalities via Exponentially (p, h)-Convex Functions

Here we introduce new class of exponentially convex function namely exponentially $(p,h)$ -convex function. We find the Hermite-Hadamard type inequalities via exponentially $(p,h)$ -convex functions. We extend the various familar results.
Enhancing the magnetic and inductive heating properties of Fe3O4 nanoparticles via morphology control.

Fe3O4 nanoparticles (NPs) with different shapes have been prepared by a 'solventless' synthesis approach to probe shape anisotropy effects on the magnetic and inductive heating properties. Various shapes including spheres, octahedrons, cubes, rods, wires, and multipods are obtained through alterations in reaction conditions such as the ratio of precursor to surfactant content and heating rate. Magnetic and Mossbauer measurements reveal better stoichiometry in anisotropic-shaped Fe3O4 NPs than that in the spherical and multipod NPs. As a result, the magnetization value of the anisotropic-shaped NPs approaches the value for bulk material (∼86 emu g-1). More surprisingly, the Verwey transition, which is a characteristic phase transition of bulk magnetite structure, is observed near 120 K in the anisotropic-shaped NPs, which further corroborates the fact that these NPs possess better stoichiometry compared to the spherical and multipod-shaped NPs. Other than the improved magnetic properties, these anisotropic-shaped NPs are more effective for hyperthermia applications. For example, compared to the conventional spherical NPs, the nanowires show much higher SAR value up to 846 W g-1, making them a potential candidate for practical hyperthermia treatment. In particular, the octahedral NPs shows an SAR value higher than the same size spherical NPs, which demonstrates the importance of occurrence of the Verwey transition in Fe3O4 NPs for better stoichiometric and higher heating.
Personal Financial Aggregation and Social Media Mining: A New Framework for Actionable Financial Business Intelligence AFBI

Consumers have been banking and trading online for several years now. More ambitious and tech savvy consumers have also been constructing an overview of their financial life by using Personal Finance software like Quicken and online tools such as Yodlee and Mint.com. Since late 1999, Personal Financial Aggregators PFAs have started offering internet based services to automate this process of account aggregation. This web account aggregation allows individuals to log onto one Web site and view all of their online accounts in one place. Online accounts that can be aggregated include financial sites bank, credit card, brokerage, insurance, etc. as well as lifestyle-based sites travel awards, email, chat rooms, etc.. The idea behind Personal Financial Aggregation is to offer consumers their own personal portal from which they can see all their finances at a glance, balance and rebalance accounts, make investments, pay bills, etc. In addition to this Web data aggregation, consumers are relying on social media sites such as facebook, tweeter and other internet forums to get financial advice from each other and also to critique various financial products and services. As a result, many Financial Institutions FIs are using social media analysis and mining to shape their businesses. FIs include consumer banks, brokerages, insurance, wealth management firms, etc. This paper presents a framework for financial institutions that combines social media mining, web mining, online advice engines, and web aggregation. This framework can be utilized by FIs to analyze online buzz about their products/services and combine those insights with web aggregation and online advice to create different revenue streams and to offer personalized bundled products and services. The authors conducted interviews with various executives at the Global Financial institutions and insurance companies to test and validate this framework. A comprehensive review of top service providers and vendors that can enable and drive this framework is also discussed in this paper, followed by managerial implications, benefits and challenges.
10 – Relational Mapping

Publisher Summary Most database modeling tools allow entering a data model in one or more high-level notations like Entity-Relationship (ER), IDEF1X, Object-Role Modeling (ORM), and Unified Modeling Language (UML), as well as in logical-level notations (like Relational). A high-level (conceptual or semiconceptual) schema must be mapped down to a logical and then physical schema in order for the database to be populated and queried. Because of the dominance of relational database systems, the relational model is used for the logical schema. The basic procedure is discussed for mapping an ORM conceptual schema onto a relational schema. This can be easily adapted to cover mapping from other notations such as entity-relationship or the UML. Furthermore, this chapter presents advanced aspects of relational mapping including the use of conceptual annotations to override default mapping choices (that is, to control how subtypes or 1:1 associations are mapped) and the fundamental constructs in relational database schemas using a genetic notation.
Epidemiological investigation on confirmed cases of schistosomiasis in Hubei Province

Objective To grasp the distribution and epidemiology of confirmed cases of schistosomiasis in Hubei Province, so as to provide the evidence for promoting the prevention and control work. Methods The confirmed cases of schistosomiasis in Hubei Province from 2010 to 2014 were epidemiologically investigated, and the prevalence characteristics and main influencing factors were analyzed. Results A total of 10 102 confirmed cases from 2010 to 2014 were surveyed. There were 1 062 local infected patients, accounting for 10.51% and including 354 repeated infections and 17 newly infected. There were 290 foreigninfected patients, accounting for 2.87%, with 206 repeated infection cases and 84 newly infected. There were 8 750 historical patients, including 2 229 patients who leaked the former schistosomiasis investigations, accounting for 22.06%; 570 patients missed treatment, accounting for 5.64%; 3 640 patients were treated with non-standard therapy, accounting for 36.03%; 2 311 patients were treated with poor medication efficacy, accounting for 22.88%. The multivariate non-conditional Logistic regression, targeting at confirmed cases in 2014, showed that, for the leaking investigations, the potential risk factors included the age, educational level, and latrine renovation (b＞0, OR＞1), the protective factors were the times of previous treatment, cattle feeding in villager team, and Oncomelania hupensis snails in surroundings (b＜0, OR＜1); for the treatment-missing, the age, educational level, snails in the surroundings of residence were risk factors (b＜0, OR＜1); for the substandard treatment, the risk factors included the occupation and snails in the surroundings of residence (b＞0, OR＞1), and the educational level and snails in the own field were protective factors (b＜0, OR＜1). Conclusions The epidemiological investigation on the confirmed cases of schistosomiasis could grasp the epidemic factors so as to improve the management and carry out the scientific control.
T-Pack: Timed Network Security for Real Time Systems

Network communication between real-time control systems raises system vulnerability to malware attacks over the network. Such attacks not only result in alteration of system behavior but also incur timing dilation due to executing injected code or, in case of network attacks, to dropped, added, rerouted, or modified packets. This work proposes to detect intrusion based on time dilation induced by time delays within the network potentially resulting in system malfunctioning due to missed deadlines. A new method of timed packet protection, T-Pack, analyzes end-to-end transmission times of packets and detects a compromised system or network based on deviation of observed time from the expected time on end nodes, well in advance of a task's deadline. First, the Linux network stack is extended with timing information maintained within the kernel and further embedded within packets for TCP and UDP communication. Second, real-time application scenarios are analyzed in terms of their susceptibility to malware attacks. Results are evaluated on a distributed system of embedded platforms running a Preempt RT Linux kernel to demonstrate its real-time capabilities.
Fostemsavir: A Novel Attachment Inhibitor for Patients With Multidrug-Resistant HIV-1 Infection.

ObjectiveTo review the efficacy and safety of fostemsavir (FTR) for the treatment of multidrug-resistant HIV-1 infection in heavily treatment-experienced adults who are failing their current antire...
The Gospel for All Peoples and Pistis Christou: A Doctrine Only for Healing the Troubled Consciences of Western Guilt-Oriented Peoples? (Part I)

Does pistis Christou, in crucial contexts in Paul’s letters, mean “faith in Christ,” “faithfulness of Christ, or “steadfast-faith of Christ”? I choose the third of these alternatives. It correlates well with the biblical doctrine of the active and suffering obedience of Christ. Moreover, the “steadfast-faith of Christ” is not merely for guilt-oriented peoples (Rom 3:29-31). It is essential to Paul’s “gospel” and is paradigmatic for all nations (Rom 2:16). Paul was Christ’s chosen emissary and was given a message and power to proclaim that divine gospel to idol worshippers. Consequently, anyone proclaiming another gospel must be cursed (Gal 1:6-9, 2:7-8).
Adjuvant chemotherapy for pulmonary sarcomatoid carcinoma: A retrospective analysis of the National Cancer Database

Abstract Objectives Pulmonary sarcomatoid carcinoma (PSC) is a rarely occurring variant of non-small cell lung cancer with sarcoma-like features. Compared with traditional non-small cell lung cancer, PSC patients typically present later and have poorer prognoses, irrespective of stage. The standard of care is resection, but guidelines for the use of adjuvant chemotherapy have not been established. To advance the development of evidence-based management algorithms for PSC after resection, a statistical analysis on a nationwide representative sample of patients was performed. Methods A retrospective cohort study was performed by querying the National Cancer Database for patients with a diagnosis of PSC between 2004 and 2015. Patients who received complete anatomical resection with or without adjuvant chemotherapy were included. Multivariable regression was used to detect factors associated with the receipt of adjuvant chemotherapy. Multivariable Cox regression of overall survival and Kaplan-Meier survival analysis on propensity-matched groups was conducted to study the association between adjuvant chemotherapy and prognosis. Results We included 1497 patients with PSC in the final analysis. Factors associated with receiving adjuvant chemotherapy were age, histology, and receipt of adjuvant radiation. The results of multivariable Cox analysis and Kaplan-Meier analysis on propensity matched groups yielded similar trends: adjuvant chemotherapy was associated with improved 5-year overall survival for stage II and III disease, but not for stage I disease. Conclusions Multiple factors are associated with receipt of adjuvant chemotherapy for PSC, and this treatment appears to be associated with improved survival in stage II and stage III, but not stage I patients.
Honey bee (Apis mellifera) colony strength and its effects on pollination and yield in highbush blueberries (Vaccinium corymbosum).

Many pollination studies with honey bees have examined the effect of colony density on crop yield and yet overlook the effect of variation in the population size of these colonies. High colony density in northern highbush blueberry has been met with concerns from beekeepers who feel higher densities will intensify outbreaks of European foulbrood (EFB, Melissococcus plutonius, Truper and de Clari), a honey bee brood disease. The purpose of this study was to confirm the prevalence of EFB in colonies pollinating blueberries and to determine whether field-level variation in the population of adult workers in colonies explained variation in blueberry fruit set and/or yield. We addressed these objectives over the course of two production seasons at 13 commercial blueberry fields in Oregon, USA, stocked with identical densities of 10 colonies/ha. We confirmed that all colonies had negligible symptoms of EFB at the start of blueberry pollination, but 53% of colonies in 2019 and 41% in 2020 had symptoms immediately following the pollination season. We also validated a method for rapidly assessing adult honey bee colony populations, namely by counting the rate of foragers returning to colonies, and it was found to be strongly correlated to true internal adult bee population independent of year and ambient temperature at the time of evaluation. Using returning forager counts, we determined there was considerable variation in the average population of colonies at each field, ranging from an estimated 10,300 to 30,700 adult worker bees per colony. While average colony strength did not predict variation in fruit set, it was related to variation in yield, independent of year. Our linear model of flight count (as a proxy for colony strength) predicts estimated yield increases of up to 25,000 kg/ha of blueberries could be achieved by colonies stronger than the recommended six frame minimum, suggesting that higher pollination benefits could be achieved without increasing hive density if stronger colonies are promoted.
Demonstrating REACT: a Real-time Educational AI-powered Classroom Tool.

We present a demonstration of REACT, a new Real-time Educational AI-powered Classroom Tool that employs EDM techniques for supporting the decision-making process of educators. REACT is a data-driven tool with a user-friendly graphical interface. It analyzes students' performance data and provides context-based alerts as well as recommendations to educators for course planning. Furthermore, it incorporates model-agnostic explanations for bringing explainability and interpretability in the process of decision making. This paper demonstrates a use case scenario of our proposed tool using a real-world dataset and presents the design of its architecture and user interface. This demonstration focuses on the agglomerative clustering of students based on their performance (i.e., incorrect responses and hints used) during an in-class activity. This formation of clusters of students with similar strengths and weaknesses may help educators to improve their course planning by identifying at-risk students, forming study groups, or encouraging tutoring between students of different strengths.
CCM3 Loss-Induced Lymphatic Defect Is Mediated by the Augmented VEGFR3-ERK1/2 Signaling.

Objective: Cerebral cavernous malformations (CCMs) can happen anywhere in the body, although they most commonly produce symptoms in the brain. The role of CCM genes in other vascular beds outside t...
An Empirical Study of the Effect of Reducing Matching Frequency in High-Level Architecture Data Distribution Management

The High-Level Architecture (HLA) is an interoperability protocol standard and implementation architecture for distributed simulation. Using HLA, concurrently executing simulation models collaboratively simulate a scenario by exchanging messages over a network. In HLA simulations, large volumes of messages are possible, potentially limiting scalability. The HLA Data Distribution Management services are designed to reduce message volume. When using those services, the HLA software determines how to route messages by repeatedly solving a computationally expensive computational geometry problem known as “matching”: given a set of axis-parallel hyper-rectangles in a multidimensional coordinate space, find all intersecting pairs of rectangles. Much effort has been devoted to performing matching as efficiently as possible. This study investigates a different approach, namely, performing matching as seldom as possible, without compromising the simulation results. A constructive entity-level combat model, similar to production military semi-automated forces systems, was developed and verified. It was then used to experimentally assess the effect of performing matching at various frequencies. The primary metric of effect was the mean time at which battlefield entities first sighted each other. Experimental results regarding the delay of first sighting times suggest that matching frequency, and thus its computational expense, can be substantially reduced without negative effects.
The grammar of possession

The Grammar of Possession: Inalienability, incorporation and possessor ascension in Guarani , is an exhaustive study of linguistic structures in Paraguayan Guarani which are directly or indirectly associated with the semantic domain of inalienability. Constructions analyzed in the book include adnominal and predicative possessive constructions, noun incorporation, and possessor ascension. Examples are drawn from a rich data base that incorporate native speaker intuitions and resources in the construction of illustrative linguistic forms as well as the analysis of the communicative use of the forms under study. The book provides a complete picture of inalienability as a coherent integrated system of grammatical and semantic oppositions in a language that has received little attention in the theoretical linguistic literature. The analysis moves from general principles to specific details of the language while applying principles of Cognitive Grammar and Functional Linguistics. There is an explicit aim to uncover the particularities of form-meaning connections, as well as the communicative and discourse functions of the structures examined. Other approaches are also considered when appropriate, resulting in a theoretically informed study that contains a rich variety of considerations.