cssi/SciSciGPT-SciSciNet huggingface dataset:
A 35–105 GHz High Image-Rejection-Ratio IQ Receiver with Integrated LO Doubler and > 40 dB IRR

This paper presents a 35–105 GHz wideband direct conversion IQ receiver and a 30–105 GHz IF receiver with integrated LO doubler in GF8HP 0.12-μm SiGe BiCMOS technology. Both receiver chips cover Q-, V-, E-, and W-bands and are flipped on a low cost RF board for connectorized measurements. The IQ receiver presents a measured flat conversion gain of 21–33 dB at 35–105 GHz and a double-sideband (DSB) noise figure (NF) of 5–12 dB. With the on-chip I/Q phase-error correction, the IQ receiver maintains better than 40 dBc image-rejection-ratio (IRR) over the entire bandwidth. The IF receiver demonstrates a measured flat conversion gain of 18–33 dB at 30–105 GHz with a similar NF as the IQ receiver. Both receivers have greater than 5 GHz IF (baseband) bandwidth. To our knowledge, this I/Q receiver achieves the state-of-the-art performance in terms of bandwidth, wideband IRR, and NF.
Beyond Hands On: Incorporating Kinesthetic Learning in an Undergraduate Paleontology Class

Hands-on learning in paleontology, and geology in general, is fairly common practice. Students regularly use rocks, fossils, and data in the classroom throughout their undergraduate career, but they typically do it sitting in a chair in a lab. Kinesthetic learning is a teaching model that requires students to be physically active while learning. Students may be involved in a physical activity during class or might be using their own bodies to model some important concept. This Element briefly discusses the theory behind kinesthetic learning and how it fits into a student-centered, active-learning classroom. It then describes in detail methods for incorporating it into student exercises on biostratigraphy, assessment of sampling completeness, and modeling evolutionary processes. Assessment data demonstrates that these exercises have led to significantly improved student learning outcomes tied to these concepts.
Does spinal anesthesia lead to postoperative urinary retention in same-day urogynecology surgery? A retrospective review.

Spinal anesthesia has been reported to be a risk factor for postoperative urinary retention (POUR) in various surgical specialties. We hypothesized that spinal anesthesia was a risk factor for POUR after outpatient vaginal surgery for pelvic organ prolapse (POP). This was a retrospective review of an urogynecology database for all outpatient POP vaginal surgeries performed in 2014 to evaluate the risk of POUR after general versus spinal anesthesia. A standardized voiding trial was performed by backfilling the bladder with 300 ml of saline. A successful trial was achieved if the patient voided two-thirds of the total volume instilled, confirmed by bladder ultrasound. Our primary outcome was to compare POUR requiring discharge with a Foley catheter between spinal and general anesthesia. Multivariate logistic regression was performed for variables with significance at p < 0.1 at the bivariate level. A total of 177 procedures were included, 126 with general and 51 with spinal anesthesia. The overall POUR rate was 48.9%. Type of anesthesia was not a risk factor for POUR. Multivariate logistic regression demonstrated that age < 55 years (adjusted odds ratio [OR] 3.73; 95% confidence interval [CI], 1.31–11.7), diabetes (adjusted OR 4.18, 95% CI 1.04–21.67), and having a cystocele ≥ stage 2 (adjusted OR 4.23, 95% CI 1.89–10) were risk factors for developing POUR. Acute urinary retention after outpatient vaginal pelvic floor surgery can vary by procedure, but overall is 48.9%. Spinal anesthesia does not contribute to POUR, but rates are higher in those women that are younger than 55 years of age, have a cystocele ≥ stage 2 preoperatively, and a history of diabetes.
The Final Years of Saturday Morning

In this chapter, O’Melia analyzes the final years of Saturday Morning in the United States. Deviating from her previous chapters’ model that focuses on a Japanese phenomenon and the popular programs that emerged around it, she concentrates on how the tropes and conventions of Japanese media as presented in the ascension of Mighty Morphin Power Rangers, Pokemon, and Yu-Gi-Oh! had become the common narrative culture of Saturday Morning. She does this by demonstrating it was these tropes and conventions that acted as the unifying force between Tai Chi Chasers, a South Korean program, and Justice League Unlimited, The Spectacular Spider-Man, and Iron Man: Armored Adventures, all American superhero programs based on intellectual properties that were not strangers to Saturday Morning scheduling.
Mating yeast cells use an intrinsic polarity site to assemble a pheromone-gradient tracking machine

The mating of budding yeast depends on chemotropism, a fundamental cellular process. The two yeast mating types secrete peptide pheromones that bind to GPCRs on cells of the opposite type. Cells find and contact a partner by determining the direction of the pheromone source and polarizing their growth toward it. Actin-directed secretion to the chemotropic growth site (CS) generates a mating projection. When pheromone-stimulated cells are unable to sense a gradient, they form mating projections where they would have budded in the next cell cycle, at a position called the default polarity site (DS). Numerous models have been proposed to explain yeast gradient sensing, but none address how cells reliably switch from the intrinsically determined DS to the gradient-aligned CS, despite a weak spatial signal. Here we demonstrate that, in mating cells, the initially uniform receptor and G protein first polarize to the DS, then redistribute along the plasma membrane until they reach the CS. Our data indicate that signaling, polarity, and trafficking proteins localize to the DS during assembly of what we call the gradient tracking machine (GTM). Differential activation of the receptor triggers feedback mechanisms that bias exocytosis upgradient and endocytosis downgradient, thus enabling redistribution of the GTM toward the pheromone source. The GTM stabilizes when the receptor peak centers at the CS and the endocytic machinery surrounds it. A computational model simulates GTM tracking and stabilization and correctly predicts that its assembly at a single site contributes to mating fidelity.
Solution of the Benchmark Control Problem by Scenario Optimization

This article introduces a scenario optimization framework for reliability-based design given measurements of the uncertain parameters. In contrast to traditional methods, scenario optimization makes direct use of the available data thereby eliminating the need for assuming a distribution class and estimating its hyper-parameters. Scenario theory provides formal bounds on the probabilistic performance of a design decision and certifies the system ability to comply with various requirements for future/unseen observations. This probabilistic certificate of correctness is non-asymptotic and distribution-free. Furthermore, chance-constrained optimization techniques are used to detect and eliminate the effects of outliers in the resulting optimal design. The proposed framework is exemplified on a benchmark robust control challenge problem having conflicting design objectives.
Connecting epistemic injustice and justified belief in health-related conspiracies

Summary In this paper, I argue that epistemic injustice in healthcare settings can contribute to patients’ rational mistrust of healthcare providers and the healthcare system, leaving these individuals vulnerable to rational belief in health-related conspiracy theories. I focus on the ways in which two kinds of epistemic injustice – testimonial injustice and hermeneutical injustice – can contribute to specifically women's rational mistrust of healthcare providers, as well as a rational mistrust of the mainstream healthcare system more generally. Once patients mistrust healthcare providers and/or the healthcare system, it seems rational for victims of these testimonial injustices seek out information from sources other than the mainstream healthcare system. This leaves them particularly vulnerable to rational belief in potentially harmful health-related conspiracy theories, especially given the easy access we all have to health-related misinformation and conspiracy via the Internet and social media. In this sense, then, experiences of epistemic injustice can contribute to individuals’ rational belief in health-related conspiracy theories.
Determination of Sample Size and Influencing Factors to Characterize Faulting in Jointed Concrete Pavements

The objective of this study is to evaluate the field variability of jointed concrete pavement (JCP) faulting and its effects on pavement performance. The standard deviation of faulting along both t...
Factors related to first-year retention rate in a public minority serving institution with nontraditional students

The authors present a comprehensive study to identify factors that affect the retention rate of first-time freshman business students in a large four-year public university. Factors include backgro...
A Review of Ethnomedicinal Plant Resources in Southern Nigeria

Background: The inadequate programs established to eradicate numerous health problems in Nigeria have led to little improvement in the health status, especially in southern Nigeria. Southern Nigeria has a high prevalence rate of malaria, typhoid, fevers, colds and chills, catarrh, flu, river blindness, respiratory disorders, eye problems and skin infections. The strain caused by the dire need to provide a financial health coverage for the family, a poorly developed health care systems and functional surveillance has led to the exploration of alternative medicine by the indigenes of southern Nigeria.This study aims at documenting information on the common plant resources employed in the ethnomedicinal practices of the indigenous people of the Southern Nigeria, and to explore ways of sensitizing genuine conservation efforts in the face of threat of genetic erosion posed to these resources due to anthropogenic activities. Materials and methods: Onsite ethnomedicinal survey in the study area was carried out between September 2019 and November 2020 to document an indigenous medicinal plant traditional knowledge. Interviews were conducted with the aid of a local language interpreter. Data were obtained using 300 semi-structured questionnaires. Consultations were made on all available information about traditional medicinal plants and ethnomedicinal surveys in Southern Nigeria. Online electronic databases including Google scholar, Research Gate, SciFinder, ScienceDirect and Open Thesis were used to search for relevant literature. Ethnomedicinal data were analyzed using the Relative frequency of citation (RFC), Fidelity level (FL), Relative popularity level (RPL), Use value (UV) and Informant Consensus Factor (ICF). Results: A total of 236 species belonging to 80 families were reported by this study. Fabaceae was the most represented family having thirty (30) plant species. The three (3) regions had varying frequencies of occurring plants species. South-Western Nigeria represented the region with the highest plant occurrence (47%) followed by South–South (31%). Leaves (42.32%) were the most common parts used in the preparation of herbal remedies. Decoctions (48.89%) were the most common method of plant preparation used in herbal remedies. Regional distribution and occurrence of ethnomedicinal plant resources of Southern Nigeria is reported here for the ﬁrst time. Conclusion: Medicinal plants play crucial role in the treatment of various ailments by the indigenous people in Southern Nigeria. This study highlights the level of species richness as well as biodiversity in the study area. Bioactivity and toxicity by in vitro and in vivo standard tests should be made on herbal drug extracts of the presented species for isolation and possible identiﬁcation of potentially active compounds
Rash after a twenty-one day unclothed African survival challenge.

A patient developed a reticulated gray-brown rash after completing a 21-day unclothed African survival challenge. During the challenge, the patient slept near a fire and inside a rock igloo. Exam and history were consistent with erythema ab igne, a rash related to heat exposure from fire or other heating sources.
Pre-breakdown arcing as proxy for DC dielectric breakdown testing of polymeric insulators

Pre-breakdown arcing is proposed as a key indicator of DC breakdown properties of polymeric dielectric materials. Voltage step-up tests were performed for films of low-density polyethylene (LDPE) at ramp rates significantly lower than is common in most studies, allowing for the observation of both breakdown and transient pre-breakdown current spikes. The distributions of the breakdowns versus applied field were compared with the more frequent pre-breakdown arcs. A strong correlation was observed for LDPE between the distribution of breakdowns in step-up tests and the distribution of pre-breakdown arcing. Pre-breakdown arcing distributions are much easier to obtain than breakdown distributions and may be an efficient indicator of the minimum field at which breakdown can occur, leading to accelerated test methods. The possible physical origins underlying pre-arcing and its relation to breakdown distributions are discussed.
A Brief History of Human Functional Brain Mapping

Publisher Summary This chapter traces a brief history of human functional brain mapping. Functional brain imaging with positron emission tomography (PET) and magnetic resonance imaging is made possible because blood flow changes locally in the brain in relation to changes in cellular activity. Even though the blood flow response is delayed somewhat in time due to a sluggish response of blood vessels to changes in neuronal activity, it is remarkable how reliable it appears to be in reflecting changes in cellular activity in the normal brain. One of the critical aspects in the emergence of PET for quantitative in vivo autoradiography in humans was the ability of the developers of the technique to take full advantage of the image reconstruction technique of filtered backprojection. The typical reaction within the scientific and industrial community to the introduction of computed tomography (CT) was that far better image reconstruction algorithms could be developed for CT and better scanners built than the ones being offered by Electrical and Musical Industries, Limited. Work on the neural correlates of human behaviors with PET began with studies of brain glucose metabolism and the tracer 18F-2-fluoro-2-deoxy-D-glucose.
LINDEMANN MELTING LAW FOR ANISENTROPIC CRYSTALS: GRAPHITE → LIQUID CARBON

The Lindemann law for the melting point of a solid has been elaborated to apply to an anisotropic system like graphite. This model is more consistent with the small value of the Gruneisen γ of graphite and the observed low pressure P,T slope of the melting line. Theoretical and experimental information is used to describe the lattice as a function of volume. To describe the overall shape of the melting line, a scaling model for liquid diamond and -graphite are used. A mixture model for the two liquids avoids an inevitable liquid-liquid phase change. The transition from the solids to the mixed liquid qualitatively reproduces the melting line indicated by experiments. Some inconsistency appears to exist between the measured (dP/dT)M for graphite and that indicated for diamond.
Synthesis of small proteoglycans substituted with keratan sulfate by rabbit articular chondrocytes.

Abstract 35S-Labeled proteoglycans produced by chondrocytes from immature and mature rabbits were fractionated on associative CsCl gradients. In all cultures, greater than 85% of the incorporated radioactivity was present in the A1 fraction (rho 1.60) as chondroitin sulfate/keratin sulfate-substituted aggregating proteoglycan monomer; the remainder was present in small proteoglycans in the A2, A3, and A4 fractions of low buoyant densities (rho 1.53, 1.45, 1.37, respectively). Detailed glycosaminoglycan analysis of the A2, A3, and A4 fractions showed dermatan sulfate-rich species were present throughout. However, in both immature and mature cultures, 30-45% of the glycosaminoglycans in the A3/A4 combined fractions were present as keratan sulfate, as shown by insensitivity to digestion with chondroitinase ABC, specific digestion with endo-beta-galactosidase, and reactivity with antibody 5D4. Immature and mature chondrocytes synthesized very similar amounts of the low buoyant density keratan sulfate proteoglycan on a per cell basis. Moreover, 51 and 37% of the total keratan sulfate produced by immature and mature chondrocytes, respectively, were present in the low buoyant density proteoglycan. Pulse-chase experiments indicated that the low buoyant density keratan sulfate was not derived from the large aggregating proteoglycan by proteolysis in the extracellular space. The small keratan sulfate proteoglycans appear to be present as a species distinct from the small dermatan sulfate proteoglycans in these cultures in that they can be separated on Q-Sepharose chromatography and sodium dodecyl sulfate-polyacrylamide gel electrophoresis. The apparent size (40-60 kDa), composition, and heterogeneity of the keratan sulfate proteoglycans suggest that they may be related to the small keratan sulfate proteoglycans of cornea.
Estrogen Receptors QUANTITATIVE STUDIES ON TRANSFER OF ESTRADIOL FROM CYTOPLASMIC TO NUCLEAR BINDING SITES

Abstract Quantitative studies were carried out on the uptake and binding of 3H-estrogen in the cytoplasm of rat uterus and the subsequent appearance of the estrogen in the nuclear fraction. At high levels of estrogen (2 x 10-8m) the 8 S binding protein in the cytosol rapidly (within 5 min) became saturated with estrogen, and within 1 hour 90% had disappeared from the cytoplasm. Concomitantly, the estrogen appeared in the nucleus. Lower concentrations of estrogen result in peaks of cytoplasmic binding at 15 to 60 min. The estrogen-binding protein extracted from the nuclear fraction was unable to bind additional estrogen, indicating that its binding sites were saturated. Movement of estrogen into the nucleus showed a straight line relationship with concentration at all levels of saturation. This strongly suggests that the native state of the estrogen-binding protein has a single estrogen binding site.
Computation of unsteady euler flows with moving boundaries and fluid-structure interactions

An algorithm for the computation of steady and unsteady inviscid, compressible, two-dimensional flows is presented. Grid generation utilizes the quadtree spatial subdivision algorithm, allowing automatic meshing of boundaries of arbitrary geometry, and allowing h-adaptivity to geometric and solution features. Internal boundaries and interfaces may move, deform, coalesce, and disintegrate arbitrarily. The flow-solver is of the High-Resolution Gudonov type. For moving boundaries, a novel feature of the algorithm is that the grid is stationary and boundaries are allowed to move across grid-lines. This is enabled by merging cells in the vicinity of boundaries to form composite cells that are topologically invariant during individual motion steps. This merging also eliminates the small-cell time-step constraint introduced by grid non-conformality. The motion of boundaries may be prescribed, or computed from aerodynamic, body, or contact forces in a coupled fashion. Two computations illustrating the capabilities of the algorithm are presented.
Equivalent forgetting rates in long-term memory for diencephalic and medial temporal lobe amnesia

Amnesia can result from damage to either the midline diencephalon or the medial temporal lobe. An important related question has been whether these two forms of amnesia result in similar or different kinds of memory impairment. Earlier studies raised the possibility that differences might exist in the rate of forgetting within long-term memory, specifically, that the forgetting rate is normal in diencephalic amnesia but abnormally rapid in medial temporal lobe amnesia. In the present study, forgetting was studied in five amnesic patients with damage to the medial temporal lobe, six amnesic patients with damage to the diencephalon, and 10 normal subjects. One hundred twenty pictures were presented to the control subjects for 1 sec each and to the amnesic patients for 8 sec each. Retention was then tested after 10 min, 2 hr, and 30-32 hr using four different procedures for testing recognition memory. The different exposure times for the pictures succeeded in matching the performance scores of both groups of amnesic patients and the control subjects at the 10 min retention interval. Both groups of amnesic patients also performed similarly to control subjects at retention delays of 2 hr and 30-32 hr. In addition, performance was nearly identical, regardless whether recognition memory was assessed by asking subjects to select the new items or the old items. The findings emphasize the similarities between medial temporal lobe and diencephalic amnesia.
Yoga and Emotion Regulation in High School Students: A Randomized Controlled Trial

Middle adolescents (15-17 years old) are prone to increased risk taking and emotional instability. Emotion dysregulation contributes to a variety of psychosocial difficulties in this population. A discipline such as yoga offered during school may increase emotion regulation, but research in this area is lacking. This study was designed to evaluate the impact of a yoga intervention on the emotion regulation of high school students as compared to physical education (PE). In addition, the potential mediating effects of mindful attention, self-compassion, and body awareness on the relationship between yoga and emotion regulation were examined. High school students were randomized to participate in a 16-week yoga intervention (n = 19) or regular PE (n = 18). Pre-post data analyses revealed that emotion regulation increased significantly in the yoga group as compared to the PE group (F (1,32) = 7.50, p = .01, and eta(2) = .19). No significant relationship was discovered between the changes in emotion regulation and the proposed mediating variables. Preliminary results suggest that yoga increases emotion regulation capacities of middle adolescents and provides benefits beyond that of PE alone.
Development and early prognosis of esophageal varices in severe chronic active liver disease (CALD) treated with prednisone.

Abstract The prevalence of gastroesophageal varices and gastrointestinal hemorrhage was determined in 124 patients with severe chronic active liver disease (CALD) receiving prednisone and followed regularly for up to 10 yr. Varices were demonstrated by contrast radiography in only 19 patients (15%). Ten had varices before therapy and nine developed them after 12–102 mo of observation (mean, 38 ± 9 mo.). The likelihood of developing varices within 5 yr after therapy was 8% in all patients and 13% after documentation of cirrhosis. Hemorrhage from varices occurred in only 1 patient, who had varices and bled once before treatment. Bleeding from other sites was commoner in the presence of varices (P
A Structure-guided Approach to Creating Covalent FGFR Inhibitors

The fibroblast growth factor receptor tyrosine kinases (FGFR1, 2, 3, and 4) represent promising therapeutic targets in a number of cancers. We have developed the first potent and selective irreversible inhibitor of FGFR1, 2, 3, and 4, which we named FIIN-1 that forms a covalent bond with cysteine 486 located in the P loop of the FGFR1 ATP binding site. We demonstrated that the inhibitor potently inhibits Tel-FGFR1-transformed Ba/F3 cells (EC(50) = 14 nM) as well as numerous FGFR-dependent cancer cell lines. A biotin-derivatized version of the inhibitor, FIIN-1-biotin, was shown to covalently label FGFR1 at Cys486. FIIN-1 is a useful probe of FGFR-dependent cellular phenomena and may provide a starting point of the development of therapeutically relevant irreversible inhibitors of wild-type and drug-resistant forms of FGFR kinases.
Ureteropelvic junction obstruction due to inflammatory pseudotumor masquerading as hydronephrosis because of a neuropathic bladder in a child with myelomeningocele

Inflammatory pseudotumors (IPTs), also known as inflammatory myofibroblastic tumors, are rare solid lesions, generally thought to be benign, which have been described in a variety of locations. We report a case of a child with a neuropathic bladder who developed a pseudotumor of the retroperitoneum that caused progressive ureteral obstruction distal to the ureteropelvic junction. Hydronephrosis as a complication of IPTs has been described with bladder and uterine IPTs; however, in our review of published reports, we found no reported cases of a retroperitoneal IPT causing proximal ureteral obstruction in a pediatric patient.
Human Low Density Lipoprotein (LDL) and Human Serum Albumin (HSA) Co‐Adsorption Onto the C18‐Silica Gradient Surface

Co-adsorption kinetics of human low density lipoprotein (LDL) and serum albumin (HSA) on hydrophilic/hydrophobic gradient silica surface were studied using Total Internal Reflection Fluorescence (TIRF) and autoradiography. Two experimental systems were examined: (1) fluorescein-labeled LDL (FITC-LDL) adsorption from a FITC-LDL + HSA solution mixture onto the octadecyldi-methylsilyl (C18)-silica gradient surface, and (2) the FITC-LDL adsorption onto the HSA pre-adsorbed on the C18-silica gradient surface. Experiments with fluorescein-labeled albumin (FITC-HSA) and unlabeled LDL have been performed in parallel. The adsorption kinetics of FITC-LDL onto the hydrophilic silica was found to be transport-limited and not affected by co-adsorption of HSA. A slower adsorption kinetics of lipoprotein onto the silica with pre-adsorbed HSA layer resulted from a slow appearance of LDL binding sites exposed by the process of HSA desorption. In the region of increasing surface density of C18 groups, the FITC-LDL adsorption rate fell below the transport-limited adsorption rate, except in the very early adsorption times. Pre-adsorption of HSA onto the C18-silica gradient region resulted in a significant decrease of both the FITC-LDL adsorption rate and adsorbed amount. The lowest FITC-LDL adsorption was found in the region of C18 self-assembled monolayer, where the pre-adsorbed HSA layer almost completely eliminated lipoprotein binding.
A probabilistic solution-generator for simulation

Abstract In a discrete-event simulation study, we are usually faced with dealing with an extremely large design space in a random environment. Our research goal in this paper is to construct a probabilistic solution generator (PSG) to generate a small candidate design set (CD). The CD should contain the solutions meeting at least a certain performance level with a high probability. The PSG is constructed using a rough-cut evaluation method rather than the simulation model in order to sift through the large design space quickly. A rough-cut evaluation of designs may be achieved through an approximate method, a heuristic approach, or a short simulation run possibly with a high error. Subsequently, the designs in the CD are to be analyzed thoroughly in the simulation model to select the best with a high degree of certainty with one of the well-known statistical comparison and selection techniques.
Long Rang Cation Order in Pb(Mg 1/3 Nb 2/3 )O 3 Complex Oxides

Long range cation order in the Pb(Mg1/3Nb2/3)O3 compound was developed through only 1 at.% cation substitution with La3+, Sc3+ or W3+. However, the dielectric/ferroelectric behavior of the chemically ordered PMN is strongly dependent on the substituting species. Generally speaking, incorporating La3+ significantly suppresses, while introducing Sc3+ moderately enhances, the ferroelectricity in PMN. The situation with the substitution with W6+ is complex due to the antiferroelectric nature of Pb(Mg1/3Nb2/3)O3.
A 512 K-bit magneto resistive memory with switched capacitor self-referencing sensing

A 512 K-bit nonvolatile magnetoresistive memory with a switched-capacitor self-referencing sensing scheme is reported. This memory is economical since it requires only one mask beyond a typical CMOS process and has rad hard, scalable, and no wear-out properties. This memory has a cell size of 2.0 mu m*10 mu m, logic buried under its cells, and a 0.3 cm/sup 2/ die. It is useful for disk caches and for replacing plated wire memories in aerospace applications. >
Longitudinal Outcomes for Victims of Child Abuse

Childhood abuse and neglect (child maltreatment) represent a common and significant public health burden. The consequences of maltreatment can be seen immediately, in the short term and in the long term. Determination of the exact prevalence of childhood maltreatment is difficult, as many cases go unreported; however in reported cases there is an estimated $124 billion annual burden on the US health-care system. The evaluation of potential maltreatment is difficult as many of the initial symptoms are subtle and can be explained with alternative illnesses or injuries. Potential immediate and short-term effects include brain injury, shaken baby syndrome and behavioral regression. The potential long-term sequelae of child maltreatment are explored in detail here and include increased risks of the development of mental health disorders, substance use disorders and chronic physical complaints during development and adulthood. Lastly, the review provides an overview of current treatment approaches for victims of childhood maltreatment.
“Crestspeak”: British Military Crested Ceramics, Military Socialization, and Collective Memory

In many parts of the world, excavations of British military sites have unearthed material reflecting lifeways in the British Empire. Specifically, studies of historical ceramics and glass have greatly advanced our understanding of status and material expression. This study highlights the current body of knowledge on British military crested ceramics, contrasting the rarity of archaeological finds with their abundance in documentary sources. An elemental stylistic analysis reveals that these crests expressed regimental affiliation as the fundamental unit of self-identification. Symbolic interpretation of these crests stresses their active role in the socialization of officers and structuring collective memory, particularly through the mess institution.
A new paradigm for serious games: Transmedia learning for more effective training and education

Abstract Serious games present a relatively new approach to training and education for international organizations such as NATO (North Atlantic Treaty Organization), non-governmental organizations (NGOs), the U.S. Department of Defense (DoD) and the U.S. Department of Homeland Security (DHS). Although serious games are often deployed as stand-alone solutions, they can also serve as entry points into a comprehensive training pipeline in which content is delivered via different media to rapidly scale immersive training and education for mass audiences. The present paper introduces a new paradigm for more effective and scalable training and education called transmedia learning. Transmedia learning leverages several new media trends including the peer communications of social media, the scalability of massively openonline course (MOOCs), and the design of transmedia storytelling used by entertainment, advertising, and commercial game industries to sustain audience engagement. Transmedia learning is defined as the scalable system of messages representing a narrative or core experience that unfolds from the use of multiple media, emotionally engaging learners by involving them personally in the story. In the present paper, we introduce the transmedia learning paradigm as offering more effective use of serious games for training and education. This approach is consistent with the goals of international organizations implementing approaches similar to those described by the Army Learning Model (ALM) to deliver training and education to Soldiers across multiple media. We discuss why the human brain is wired for transmedia learning and demonstrate how the Simulation Experience Design Method can be used to create transmedia learning story worlds for serious games. We describe how social media interactions and MOOCs may be used in transmedia learning, and how data mining social media and experience tracking can inform the development of computational learner models for transmedia learning campaigns. Examples of how the U.S. Army has utilized transmedia campaigns for strategic communication and game-based training are provided. Finally, we provide strategies the reader can use today to incorporate transmedia storytelling elements such as Internet, serious games, video, social media, graphic novels, machinima, blogs, and alternate reality gaming into a new paradigm for training and education: transmedia learning.
The Littlewood-Offord problem in high dimensions and a conjecture of Frankl and Füredi

We give a new bound on the probability that the random sum ξ1v1+…+ξnvn belongs to a ball of fixed radius, where the ξi are i.i.d. Bernoulli random variables and the vi are vectors in Rd. As an application, we prove a conjecture of Frankl and Furedi (raised in 1988), which can be seen as the high dimensional version of the classical Littlewood-Offord-Erdős theorem.
Review: Omega-3 fatty acid supplements provide no protective benefit in cardiovascular disease

Source Citation Kwak SM, Myung SK, Lee YJ, Seo HG; Korean Meta-analysis Study Group. Efficacy of omega-3 fatty acid supplements (eicosapentaenoic acid and docosahexaenoic acid) in the secondary pre...
A multi-echelon queueing model with dynamic priority scheduling

Abstract In this paper, we consider a multiple finite source queueing model with multiple servers and a nonpreemptive dynamic priority service discipline. The model consists of several classes of customers each of which calls for service at the service facility after spending a random amount of time at the source. The service facility has several servers for serving all customer classes. The service time of customers is exponentially distributed. A nonpreemptive dynamic priority service discipline is used by the servers. In this type of scheduling, a customer's priority function value increases linearly with actual waiting time in the queue. We propose a recursive algorithm that approximates the mean waiting time in the queue of each type of customer classes. Although our solution is only approximate, results from a variety of test problems indicate that the approximation is quite accurate.
Anion exchange fractionation of serum proteins versus albumin elimination.

Abstract Elimination of albumin, constituting more than 50% of total serum proteins, allows increased protein loads on immobilized pH gradient (IPG) gels and better visualization of low-abundance proteins; however, it may result in the loss of albumin-bound low-abundance proteins. In this study, we report the prefractionation of serum proteins by batch anion exchange chromatography into three fractions: one containing proteins with isoelectric points (pI values) higher than the pI of albumin, a second fraction containing proteins with pI values in the same range as the pI of albumin, and a third fraction containing proteins with pI values lower than the pI of albumin. This procedure uses common instrumentation, is carried out under denaturing conditions, and takes less than 30 min. We also report the loss of a clinically established prostate cancer serum biomarker, prostate-specific antigen (PSA), after albumin is eliminated using two commercially available albumin elimination kits: one that uses Cibacron Blue F3GA, which achieves albumin depletion through dye–ligand binding, and one that uses specific albumin antibody. The loss of PSA secondary to albumin elimination exceeded that after batch anion exchange serum sample prefractionation.
The Empirical Risk-Return Relation: A Factor Analysis Approach

A key criticism of the existing empirical literature on the risk-return relation relates to the relatively small amount of conditioning information used to model the conditional mean and conditional volatility of excess stock market returns. To the extent that financial market participants have information not reflected in the chosen conditioning variables, measures of conditional mean and conditional volatility - and ultimately the risk-return relation itself - will be misspecified and possibly highly misleading. We consider one remedy to these problems using the methodology of dynamic factor analysis for large datasets, whereby a large amount of economic information can be summarized by a few estimated factors. We find that three new factors, a volatility, risk premium, and real factor, contain important information about one-quarter ahead excess returns and volatility that is not contained in commonly used predictor variables. Moreover, the factor-augmented specifications we examine predict an unusual 16-20 percent of the one-quarter ahead variation in excess stock market returns, and exhibit remarkably stable and strongly statistically significant out-of-sample forecasting power. Finally, in contrast to several pre-existing studies that rely on a small number of conditioning variables, we find a positive conditional correlation between risk and return that is strongly statistically significant, whereas the unconditional correlation is weakly negative and statistically insignificant.
Best Practices in Managing Diversity

The views expressed by various participants at a workshop on diversity organized by the National Academy of Engineering's Committee on Diversity in the Engineering Workforce in October 2001 are summarized. A common view was that employee diversity has a positive effect on a company's bottom line in that it allows the company to meet the needs of a marketplace that itself is becoming increasingly diverse and global. The benefits that diversity confers in raising employee creativity were also cited. The key components of a successful diversity program are outlined. The need for corporations, universities, and professional associations to work together in this area is stressed.
Voluntary exercise: Effects on ethanol-induced sleep in the C57BL/6J mouse

After 5 weeks of voluntary wheel running, C57BL/6J mice were significantly resistant to the sleep-inducing effects of ethanol. Sixty-four mice, 32 males and 32 females, were assigned to wheel (free access to a running wheel in the home cage) or no-wheel conditions. At the end of the training period, the animals were removed from the exercise cages and tested for sensitivity to ethanol (3.16 g/kg, 20% w/v), assessed by loss-of-righting reflex (LORR). Exercised animals showed significantly longer latency to LORR (fall time) and shorter duration of LORR (sleep time). Exercise caused a significant decrease in body weight in male, but not female, mice. The present results suggest that exercise training may be effective in reducing ethanol-induced sleep.
Quantization of Newton's constant in certain supergravity theories☆

Abstract We show that the nonlinear sigma model can be coupled to supergravity only if Newton's constant is an integral multiple of 1/ F π 2 .
R69-22 Computation over Galois Fields Using Shiftregisters

This paper is little more than a rehash of well-known results, mostly from the paper of Bartee and Schneider (Information and Control, vol. 6, pp. 79-98, 1963) and from Elspas (IRE Trans. Circuit Theory, vol. CT-6, pp. 45-60, 1959). The former is not even referenced. Standard algebraic theorems, notably the Cayley-Hamilton theorem, and well-known results on companion matrices are (unnecessarily) demonstrated when a reference to, e. g., Birkhoff-Mac-Lane would have sufficed. Fig. 2 of this paper is identical to a figure on page 117 of W. W. Peterson, Error Correcting Codes (Cambridge, Mass.: M.I.T. Press, and New York: Wiley, 1961). One wonders why this paper was written at all, and what kind of review procedure it did (or did not) receive.
Recurrent nephrogenic adenoma in a 10-year-old boy with prune belly syndrome : a case presentation

Nephrogenic adenoma is a rare benign lesion of the urinary tract that is associated with a history of irritation or injury of the urothelium. Predisposing factors include infection, calculi, surgery, trauma, and renal transplantation. Nephrogenic adenoma commonly presents with lower urinary tract symptoms or hematuria. We present the case of recurrent nephrogenic adenoma in a 10-year-old boy with a history of prune belly syndrome and discuss management of this disease in the pediatric population. To our knowledge this represents the first reported case of recurrent nephrogenic adenoma associated with prune belly syndrome.
A Randomized Experiment of a Cognitive Strategies Approach to Text-Based Analytical Writing for Mainstreamed Latino English Language Learners in Grades 6 to 12

Abstract This study reports Year 1 findings from a multisite cluster randomized controlled trial of a cognitive strategies approach to teaching text-based analytical writing for mainstreamed Latino English language learners (ELLs) in 9 middle schools and 6 high schools. There were 103 English teachers stratified by school and grade and then randomly assigned to the Pathway Project professional development intervention or control group. The Pathway Project trains teachers to use a pretest on-demand writing assessment to improve text-based analytical writing instruction for mainstreamed Latino ELLs who are able to participate in regular English classes. The intervention draws on well-documented instructional frameworks for teaching mainstreamed ELLs. Such frameworks emphasize the merits of a cognitive strategies approach that supports these learners’ English language development. Pathway teachers participated in 46 hrs of training and learned how to apply cognitive strategies by using an on-demand writing a...
Quasi-steady shape and drag of deformable bubbles and drops

Abstract The quasi-steady shape and drag of isolated drops and bubbles are reviewed in terms of quantitative results, particularly for deformed conditions. Data in the literature were investigated to provide a comprehensive description of observed theoretical, experimental and numerical trends. New descriptions of the aspect ratio and quasi-steady drag coefficient were developed which approach the theoretical limits for creeping flow and attached thin boundary layer conditions, while representing experimental data and resolved-surface simulations at other conditions (many of which are only recently available). These relationships are novel in the sense that they are formulated in terms of the local Weber and Reynolds numbers (as well as density and viscosity ratios), as opposed to static parameters only valid at terminal velocity conditions (e.g. Bond number and Morton numbers). The results indicate that aspect ratio is a unique function of Weber number for fluid particle Reynolds numbers over 100 (especially for clean bubbles and liquid drops in a gas). This is consistent with theoretical results for small deformations. General relations were developed for minimum drag (for a sphere) maximum drag (at maximum-deformation), from which drag increments for intermediate deformation could be defined. These increments correlated especially well with Weber number for clean bubbles and liquid drops in a gas in terms of a group parameter WeRe p 0.2 . Further research is necessary to integrate these results with effects of neighboring fluid particles and/or walls.
Formal modeling of approximate relations in biochemical systems.

Aiming to satisfy the need for the formalization of semiquantitative reasoning in the analysis of biochemical systems, the O[M] formalism for reasoning with orders of magnitude and approximate relations has been developed. It is based on seven primitive relations among quantities and compound relations which are formed as implicit disjunctions of primitives. O[M] can perform inferences by using formal approximate relations, algebraic equations, inequalities, if–then rules, assumptions, and goals. The applications discussed include Michaelis–Menten kinetics, different modes of inhibition of an enzymatic reaction, analysis of fluxes in biochemical networks, and identification of rate-limiting steps of biochemical pathways. In these applications, O[M] provides a medium for acquisition and formalization of previously informal concepts, analysis of systems at the order-of-magnitude level of detail, and automation of commonsense reasoning.
Strontium in Milk. I. Removal by Means of Reverse-Flow Ion Exchange Columns

Summary Milk from two Jersey cows dosed orally with strontium 89 and calcium 45 was mechanically separated into skimmilk and cream. These radioactive isotopes were removed from the skimmilk by use of an upward-flow ion exchange resin column. Dowex 50W-X12, Dowex 50W-X4, and Duolite C-20 were used. The calcium form of ecah resin was more effective in removal of the isotopes than was the sodium form. Between 70 and 80% of the Sr 89 and Ca 45 in the skimmilk was removed from the second 100ml. passed through the column; whereas, in the tenth 100ml., 50% of each isotope was removed, using either of the Dowex resins. The Duolite resin was not as effective when used under these conditions. An experiment in which Sr 89 and Ca 45 were put directly into skimmilk and allowed to stand for 16 hr. resulted in removals which followed very closely those of the experiment with skimmilk from dosed cows. However, a higher percentage of Sr 89 was removed than from the skimmilk of dosed cows. Treated milk contained more calcium, had a lower pH, greater titratable acidity, and shorter rennet coagulation time than untreated milk. Resin preference of strontium over calcium was shown.
Cluster beam sources: Predictions and limitations of the nucleation theory

Abstract The goal here is to ascertain the range of cluster properties and the limits of the validity of the nucleation theory for the prediction of the dynamics of formation of the condensed phase in highly underexpanded, supersonic free jet sources. These sources will be discussed, very briefly, in context to other cluster sources, with the special aim of comparing the nucleation phenomena. Results are presented for a variety of free jet sources applied to the condensation of metals at low pressures with or without carrier gas. The current controversy over whether or not free jet pure metal expansions can produce clusters in the 1000 atom range from starting pressures in the 1 to 10 Torr regime will be discussed.
Effects of tissue transglutaminase on retinoic acid-induced cellular differentiation and protection against apoptosis

Retinoic acid (RA) and its various synthetic analogs affect mammalian cell growth, differentiation, and apoptosis. Whereas treatment of the human leukemia cell line HL60 with RA results in cellular differentiation, addition of the synthetic retinoid,N-(4-hydroxyphenyl) retinamide (HPR), induces HL60 cells to undergo apoptosis. Moreover, pretreatment of HL60 cells as well as other cell lines (i.e. NIH3T3 cells) with RA blocks HPR-induced cell death. In attempting to discover the underlying biochemical activities that might account for these cellular effects, we found that monodansylcadaverine (MDC), which binds to the enzyme (transamidase) active site of tissue transglutaminase (TGase), eliminated RA protection against cell death and in fact caused RA to become an apoptotic factor, suggesting that the ability of RA to protect against apoptosis is linked to the expression of active TGase. Furthermore, it was determined that expression of exogenous TGase in cells exhibited enhanced GTP binding and transamidation activities and mimicked the survival advantage imparted by RA. We tested whether the ability of this dual function enzyme to limit HPR-mediated apoptosis was a result of the ability of TGase to bind GTP and/or catalyze transamidation and found that GTP binding was sufficient for the protective effect. Moreover, excessive transamidation activity did not appear to be detrimental to cell viability. These findings, taken together with observations that the TGase is frequently up-regulated by environmental stresses, suggest that TGase may function to ensure cell survival under conditions of differentiation and cell stress.