cssi/SciSciGPT-SciSciNet huggingface dataset:
Resonant response of harbours: an equivalent-circuit analysis

The surface-wave response of a harbour to a prescribed, incident wave is calculated on the hypotheses of shallow-water theory, an ideal fluid, and a narrow mouth, M. An equivalent electrical circuit is constructed, in which the incidentwave displacement in M appears as the input voltage and the flow through M appears as the input current. This circuit contains a radiation impedance, ZM, which comprises resistive and inductive terms, and a harbour impedance, ZH, which comprises an infinite sequence of parallel combinations of inductance and capacitance that bear a one-to-one correspondence with the natural modes of the closed harbour, together with a single capacitor, which corresponds to the degenerate mode of uniform displacement and dominates the response of the harbour as a Helmholtz resonator. Variational approximations to ZH and ZM are developed. The equivalent circuit exhibits parallel resonance at the resonant frequencies of the closed harbour, ωn, and series resonance at a second set of frequencies, corresponds to the Helmholtz mode. A narrow canal between the coastline and the harbour is represented by a four-terminal network between ZM and ZH. It is shown that narrowing the harbour mouth and/or increasing the length of the canal does not affect the mean response of the harbour to a broad-band, random input except in the Helmholtz mode, but that it does increase significantly the response in that mode, which may dominate tsunami response. The general results are applied to circular and rectangular harbours. The numerical calculation of ZH for an arbitrarily shaped harbour is discussed.
Population structure and dynamics of big brown bats (Eptesicus fuscus) hibernating in buildings in Indiana.

Abstract We monitored 63 buildings in Indiana serving as hibernacula for big brown bats for up to six winters. Fidelity of individuals to roosts averaged 21.4% in buildings with maternity colonies and 33.3% in buildings without maternity colonies, although this difference was not significant. There was much turnover, both within and among years, some bats being present one year, absent for a year or two and then returning. The sex ratio of hibernating bats was male biased (65.6% males) in buildings with maternity colonies and female biased in buildings lacking maternity colonies (65.2% female). Most big brown bats in Indiana hibernate in heated buildings rather than in caves or mines.
Race and Rally Effects: Black Voting Behavior in Response to Attacks on Barack Obama

There are numerous popular examples of blacks rallying around besieged black celebrities and politicians. Do voters behave similarly if they believe that President Obama is being attacked because of his race? I answer this question using a survey embedded experiment. The findings could shed light on predicted black voting behavior in the 2012 presidential election.
Evolutionary Design of Low Molecular Weight Organic Anolyte Materials for Applications in Nonaqueous Redox Flow Batteries

The integration of renewable energy sources into the electric grid requires low-cost energy storage systems that mediate the variable and intermittent flux of energy associated with most renewables. Nonaqueous redox-flow batteries have emerged as a promising technology for grid-scale energy storage applications. Because the cost of the system scales with mass, the electroactive materials must have a low equivalent weight (ideally 150 g/(mol·e−) or less), and must function with low molecular weight supporting electrolytes such as LiBF4. However, soluble anolyte materials that undergo reversible redox processes in the presence of Li-ion supports are rare. We report the evolutionary design of a series of pyridine-based anolyte materials that exhibit up to two reversible redox couples at low potentials in the presence of Li-ion supporting electrolytes. A combination of cyclic voltammetry of anolyte candidates and independent synthesis of their corresponding charged-states was performed to rapidly screen for t...
Gastric Cancer and Helicobacter pylori

Chronic atrophic gastritis has been identified as a precursor of gastric cancer [1]. Since Helicobacter pylori is a cause of chronic gastritis [2], the possible role of H. pylori infection in gastric carcinogenesis deserves attention. This has been investigated in populations with different risks of gastric cancer in Colombia and New Orleans (USA).
Smoldering Multiple Myeloma: Emerging Concepts and Therapeutics

Smoldering multiple myeloma (SMM) is a pre-malignant condition with an inherent risk for progression to multiple myeloma (MM). The 2014 IMWG guidelines define smoldering multiple myeloma as a monoclonal gammopathy disorder with serum monoclonal protein (IgG or IgA) ≥30 g/L or urinary monoclonal protein ≥500 mg per 24 h and/or clonal bone marrow plasma cells 10-60 % without any myeloma-defining events or amyloidosis. The risk for progression of SMM to MM vary based on clinical, laboratory, imaging, and molecular characteristics. Observation, with periodic monitoring is the current standard of care for SMM. Over last few years, research advances in SMM have led to the delineation of newer risk factors for progression and identification of a "high-risk" group that would potentially benefit from early treatment. This review focuses on advances in the SMM risk-stratification model and recent clinical trials in this patient population.
The Tradition of Probabilism and the Moral Status of the Early Embryo

WITHIN THE PAST few decades, a number of Catholic theologians have raised questions about the moral status of the human zygote and early embryo. Richard McCormick describes the embryo during the first two weeks as "nascent human life" but does not consider it an "individual human life" until later; Charles Curran concurs, stating that "truly human life" comes into being two to three weeks after fertilization; Albert Di Ianni proposes that the bodily continuity of a human existence begins only several weeks after conception; and Karl Rahner asserts that during the first few weeks the existence of a human subject is seriously doubtful. Such speculations have arisen within the context of an authoritative Church teaching: the Catholic Church, in its official magisterium, asserts that human life must be given equal protection at all stages from fertilization through adulthood. In raising questions about this authoritative teaching, theologians rely on three types of material. They examine the history of Catholic teaching on prenatal life, a tradition which is somewhat less uniform than is often recognized. They investigate the implications of philosophical theories of human nature, especially the Thomistic anthropology which is traditional in the Church and believed to be most consistent with its doctrinal position. And they study the relevance of the biological facts uncovered by contemporary scientific research, some of which appear to raise problems for the Church's current position. Theologians have found good reasons for calling present Church teaching into question, and hence appear to be justified in their speculations.
Core tunneling: Variation-aware voltage noise mitigation in GPUs

Voltage noise and manufacturing process variation represent significant reliability challenges for modern microprocessors. Voltage noise is caused by rapid changes in processor activity that can lead to timing violations and errors. Process variation is caused by manufacturing challenges in low-nanometer technologies and can lead to significant heterogeneity in performance and reliability across the chip. To ensure correct execution under worst-case conditions, chip designers generally add operating margins that are often unnecessarily conservative for most use cases, which results in wasted energy. This paper investigates the combined effects of process variation and voltage noise on modern GPU architectures. A distributed power delivery and process variation model at functional unit granularity was developed and used to simulate supply voltage behavior in a multicore GPU system. We observed that, just like in CPUs, large changes in power demand can lead to significant voltage droops. We also note that process variation makes some cores much more vulnerable to noise than others in the same GPU. Therefore, protecting the chip against large voltage droops by using fixed and uniform voltage guardbands is costly and inefficient. This paper presents core tunneling, a variation-aware solution for dynamically reducing voltage margins. The system relies on hardware critical path monitors to detect voltage noise conditions and quickly reacts by clock-gating vulnerable cores to prevent timing violations. This allows a substantial reduction in voltage margins. Since clock gating is enabled infrequently and only on the most vulnerable cores, the performance impact of core tunneling is very low. On average, core tunneling reduces energy consumption by 15%.
The network renovation experience and summary for Regional health of Yuhua district

Nanjing city Yuhuatai district successfully built in electronic health records as the core of the regional health informatization construction,before the old network mode is dated,through the upgrading,realize the district health information center, community health service centers,community health service station of the three network interconnection,data sharing.Yuhuatai health information center of internal network by radio and communication lines are formed in a ring network,each belonging to a medical institutions use this project has put its network all transformed into network professional network architecture
The Activation of Unconscious Fantasies in Behavioral Treatments

The learning of new responses and the deconditioning of maladaptive behaviors are identified as the principal mutative factors in behavioral treatments in most discussions found in the behavior therapy literature. In this chapter a different perspective will be offered; behavioral treatments will be discussed from the vantage point of a theoretical construct that is traditionally associated with psychoanalysis—the unconscious fantasy. The discussion will proceed as follows: A rationale for considering alternative or additional ways of accounting for behavior change in the behavior therapies will be presented. The thesis will be advanced that the construct unconscious fantasy, as it is used by psychoanalytic theorists, refers to many of the same phenomena that commonly employed constructs such as nonspecific effects, cognitive mediation, expectancies, and relationship variables do when they are discussed in the behavioral/experimental literature.
Creative Discomfort: The Culture of the Gelfand Seminar at Moscow University

Israel Gelfand’s weekly seminar at Moscow State University, which ran continuously from 1943 to 1989, has gained a legendary status in the Russian mathematics community. It evokes a mixture of admiration and revulsion. Did the style of the seminar merely reflect the eccentric personality of its leader, or did it indicate some broader cultural patterns? Did the seminar thrive despite its offensive style, or was the style part of the enigma? How does today’s perspective of the memoirists differ from the contemporary perceptions of the seminar? To start answering these questions, we will place the Gelfand seminar in the social context of postwar Soviet mathematics.
The Individual and Society

Underlying the differences in approach between Carlyle and Tennyson is their basic disagreement about man himself, the one ultimately despairing, the other ultimately hopeful. Murray Baumgarten has said of Carlyle: ‘He believed democracy could never control itself, for he had no faith in rationality or mediating institutions. Therefore for him we cannot be democratic and rational individuals; we must be individuals in the imperialist Calvinist mode, each man his own hero, each woman perhaps her own heroine.’1 Since Carlyle ultimately came to believe that most men and women were ‘unheroic’ and needed to be shown and told what to do, his message soon became largely ignored and he himself sank into the despair of his old age. Tennyson, on the other hand, while obviously not a champion of democracy (he was active in the cause of Governor Eyre), did have faith both in the ability of men and women to be ‘rational’ and in mediating institutions, the most important of which were church and family.
Confirmation of high prevalence of BAP1 inactivation in mesothelioma.

7564 Background: Efforts to elucidate tumorigenic mutations in mesothelioma are essential to advance therapy. Prior efforts to characterize the molecular heterogeneity of this disease have been limited by sample condition and testing platforms. Herein, we describe efforts to prospectively test patients using next-generation sequencing with matched patient germline controls. Methods: Sequential mesothelioma patients were approached for consent to our IRB protocol NCT01775072 to perform MSK-IMPACT (Integrated Mutation Profiling of Actionable Cancer Targets), a comprehensive molecular profiling platform based on solution-phase exon capture and next generation sequencing to detect somatic genetic alterations in FFPE tumor specimens. MSK-IMPACT involves hybridization capture and deep sequencing of all protein-coding exons of 341 key cancer-associated genes, including all genes that are druggable by approved therapies or are targets of experimental therapies being investigated in clinical trials at MSKCC. Resul...
Computational methods for identifying and characterizing the human gene regulatory regions and cis-elements

The identification of functional regulatory regions and cis-elements is a preliminary step toward the reconstruction of gene regulatory networks. Comparative genomics has been demonstrated to be a powerful approach for motif discovery. However, the accurate alignment of complex genomic sequences, especially those of mammalians, remains a computational challenge. In chapter 2, we propose a novel pairwise alignment system, ACANA, to improve the alignment quality of genomic sequences. Compared with top competing alignment tools, ACANA achieves better alignment quality in aligning divergent sequences for both local and global alignments. When applied to the upstream sequences of human-mouse orthologs, ACANA is able to reliably detect the conserved functional regions containing most cis-elements. Statistical motif modeling is another fundamental computational approach for motif prediction in large genome sequence. In chapter 3, we introduce the mixture of optimized Markov models to reduce false motif discovery rate in large genomic sequences. Our model is not only able to incorporate most dependency information within a motif by optimizing the arrangement of motif positions, but also flexible for adjusting model complexity limited by the size of training data. We implement the mixture model in our OMiMa system. Using OMiMa, we demonstrate that our model can improve motif prediction accuracy. Although the reconstruction of complete human gene regulatory networks, at present, remains a distant hope, it is still possible to infer some distinct features of the networks from the available data. In chapter 4, we present an example of inferring major evolutionary features of human gene regulatory networks by combining information from both gene sequence data and functional annotations. We systematically analyze the association between gene function and upstream region conservation for human-rodent orthologs. Our study shows that upstream regulatory regions of developmental transcription regulators, such as Hox genes, are extremely conserved while those of catalytic enzymes are significantly less conserved. We suggest that developmental and other important regulators constitute the central hub of human gene regulatory networks.
PREDICTION OF GLYCOSYLATION SITE-OCCUPANCY USING ARTIFICIAL NEURAL NETWORKS

Abstract A novel neural network-based model was developed to predict N -linked glycosylation site-occupancy characteristics. The model classified potential glycosylation sites as displaying variable site-occupancy or robust glycosylation when produced by CHO cell cultures under normal growth conditions. The term variable site-occupancy describes heterogeneous glycan attachment to a specified protein site. This phenomenon results in a heterogeneous mixture of glycosylated and unglycosylated proteins when produced in mammalian cell culture. The model input consists of amino acid residues around the site of glycosylation. Simulation of the model strongly correlated with previously published experimental results by Kasturi et al. (1997) and Mellquist et al. (1998).
Low grade b-cell non-Hodgkin lymphomas (NHL) involving the central nervous system (CNS): An analysis from the National Cancer Database (NCDB).

e13083Background: CNS involvement from low grade B-cell NHL is rare and has only been reported as case series. The distribution, demographics and outcomes of patients with low grade B-cell CNS NHLs...
Safety of currently licensed hepatitis B surface antigen vaccines in the United States, Vaccine Adverse Event Reporting System (VAERS), 2005-2015.

Abstract Introduction Currently four recombinant hepatitis B (HepB) vaccines are in use in the United States. HepB vaccines are recommended for infants, children and adults. We assessed adverse events (AEs) following HepB vaccines reported to the Vaccine Adverse Event Reporting System (VAERS), a national spontaneous reporting system. Methods We searched VAERS for reports of AEs following single antigen HepB vaccine and HepB-containing vaccines (either given alone or with other vaccines), from January 2005 - December 2015. We conducted descriptive analyses and performed empirical Bayesian data mining to assess disproportionate reporting. We reviewed serious reports including reports of special interest. Results VAERS received 20,231 reports following HepB or HepB-containing vaccines: 10,291 (51%) in persons 18 years; for 1485 (7.3%) age was missing. Dizziness and nausea (8.4% each) were the most frequently reported AEs following a single antigen HepB vaccine: fever (23%) and injection site erythema (11%) were most frequent following Hep-containing vaccines. Of the 4444 (22%) reports after single antigen HepB vaccine, 303 (6.8%) were serious, including 45 deaths. Most commonly reported cause of death was Sudden Infant Death Syndrome (197). Most common non-death serious reports following single antigen HepB vaccines among infants aged 18 years. Most common vaccination error following single antigen HepB was incorrect product storage. Conclusions Review current U.S.-licensed HepB vaccines administered alone or in combination with other vaccines did not reveal new or unexpected safety concerns. Vaccination errors were identified which indicate the need for training and education of providers on HepB vaccine indications and recommendations.
Heavy neutral leptons at FASER

We study the prospects for discovering heavy neutral leptons at Forward Search Experiment (FASER), the newly proposed detector at the LHC. Previous studies showed that a relatively small detector with $\ensuremath{\sim}10\text{ }\text{ }\mathrm{m}$ length and $\ensuremath{\lesssim}1\text{ }\text{ }{\mathrm{m}}^{2}$ cross sectional area can probe large unconstrained parts of parameter space for dark photons and dark Higgs bosons. In this work, we show that FASER will also be sensitive to heavy neutral leptons that have mixing angles with the active neutrinos that are up to an order of magnitude lower than current bounds. In particular, this is true for heavy neutral leptons produced dominantly in $B$-meson decays, in which case FASER's discovery potential is comparable to the proposed SHiP detector. We also illustrate how the search for heavy neutral leptons at FASER will be complementary to ongoing searches in high-${p}_{T}$ experiments at the LHC and can shed light on the nature of dark matter and the process of baryogenesis in the early Universe.
Informational masking of calm speech targets by emotional speech maskers

Recent research suggests that some types of emotional speech are more intelligible than others when presented in background noise (Dupuis & Pichora-Fuller, 2015). Yet, emotional speech can often be present as the background noise itself. Attentional mechanisms and auditory stream segregation capabilities likely impact target word recognition in these situations with emotional speech maskers. The present study examined calm target sentences in masking background combinations of four emotions (calm, sad, happy, and angry) and two masker types (2-talker babble and speech-shaped noise). The emotion categories differ from one another on perceptual dimensions of activation (low to high) and pleasantness (unpleasant to pleasant). Speech-shaped noise maskers were spectrally and temporally similar to the 2-talker babble maskers. Performance was compared between the two masker type conditions to quantify the amount of informational masking induced by different emotional speech maskers. Furthermore, the number of ta...
Deactivation Studies of the Cs/Cu/ZnO And Alkali/MoS2 Alcohol Synthesis Catalysts

Abstract Cu/ZnO and MoS 2 catalysts promoted by heavy alkali have been shown to produce alcohol mixtures consisting of isobutanol/methanol and ethanol/methanol, respectively, as the major products. The two catalyst systems exhibit contrasting behavior upon exposure to iron-carbonyl containing CO-rich synthesis gas. While the molybdenum-based catalysts remain active, the copper-based catalysts exhibit selectivity changes and deactivation proportional to the iron deposition rates. The iron centers function as Fischer-Tropsch sites for the synthesis of linear high molecular weight hydrocarbons, and the wax-like materials produced lead to fouling of the catalyst. Alternative deactivation mechanisms, including catalyst sintering and loss of the alkali promoter, have been addressed and found to be less significant than that caused by iron-generated hydrocarbons.
CHAPTER 4 – RESEARCH-SCALE EXPERIMENTATION ON THE PRODUCTION AND PURIFICATION OF SPALLOGENIC 68Ge AT LOS ALAMOS FOR NUCLEAR MEDICINE APPLICATIONS

Abstract The 68Ge-68Ga generator system is of current interest in diagnostic nuclear medicine for positron emission tomography. The parent isotope is produced in high yield at LAMPF by the spallation of RbBr targets with medium-energy protons, and laboratory-scale experiments to develop a procedure for the recovery and decontamination of radiogermanium have been conducted. Following target dissolution, distillation, and solvent extraction techniques, purified 68Ge has been quantitatively obtained at microcurie activity levels. Initial experience in the hot-cell processing of production targets is also presented.
Ataxia in long term survivors of lung cancer after whole brain radiation therapy (WBRT).

e20656Background: Ataxia is a delayed neurological adverse effect of whole brain radiation therapy (WBRT). It has not been well studied in lung cancer survivors due to the short survival after brai...
Ductal Carcinoma In Situ: Risk Factor or Cancer

Ductal carcinoma in situ (DCIS) is considered a preinvasive breast cancer because the cells have yet to breach the ductal wall. DCIS progresses to invasive cancer at a rate of 30–50%. There remains great debate as to whether DCIS truly is cancer or simply a marker of cancer risk. With that there is also controversy about the need for therapy for DCIS. The outcome of patients with DCIS is in general favorable, but even following treatment, patients with DCIS can recur, even leading to death in some cases. In this chapter, we review the data regarding whether DCIS is a marker of cancer risk or early cancer. While there is survival benefit with surgery and radiotherapy, treatment needs to be personalized, and better predictors of outcome need to be developed and tested in clinical trials to better implement therapeutic decision-making.
The Pivot: Neoconservatives, the Philippines, and the Democracy Agenda

This chapter locates the origins of the post-Cold War neoconservative democracy agenda in Reagan administration policy toward the Philippines. Neoconservatives such as Paul Wolfowitz concluded the repressive Marcos dictatorship fueled the rise of communism in the archipelago. They played a key role in shifting Reagan administration policy from support for authoritarianism toward encouragement for democratic reform. In so doing, the neoconservatives had articulated and implemented a new foreign policy vision that posited democratization as the best inoculant against instability and claimed to cohere realism and idealism. By excavating the contingent, contested articulation of the neoconservative democracy agenda in the Reagan administration, this chapter reveals the period as a key turning point in the history of US democracy promotion.
An update of cyclooxygenase (COX)-inhibitors in epilepsy disorders.

Introduction: Neuroinflammation has a critical role in brain disorders. Cyclooxygenase (COX) is one of the principal drug targets for the reduction of neuroinflammation; however, studies have yield...
Mindsets: A View From Two Eras:

A growth mindset is the belief that human capacities are not fixed but can be developed over time, and mindset research examines the power of such beliefs to influence human behavior. This article offers two personal perspectives on mindset research across two eras. Given recent changes in the field, the authors represent different generations of researchers, each focusing on different issues and challenges, but both committed to "era-bridging" research. The first author traces mindset research from its systematic examination of how mindsets affect challenge seeking and resilience, through the ways in which mindsets influence the formation of judgments and stereotypes. The second author then describes how mindset research entered the era of field experiments and replication science, and how researchers worked to create reliable interventions to address underachievement-including a national experiment in the United States. The authors conclude that there is much more to learn but that the studies to date illustrate how an era-bridging program of research can continue to be generative and relevant to new generations of scholars.
Ease of EVs: Exploring factors that influence battery consumption

Battery electric vehicles (BEVs) are becoming increasingly popular, showing annual sales growth, yet adoption is still limited. Maximizing distance driven between charges can improve user perceptio...
Elimination of Sestrin 2 Compromises Viability in Extracellular Matrix-Detached SKOV3 Ovarian Cancer Cells

Epithelial ovarian carcinoma (EOC) is considered the deadliest gynecological cancer, largely due to the fact that it is often diagnosed once the cancer has already metastasized, thus making the disease more difficult to treat. Throughout metastasis, ovarian epithelial cancer cells must overcome many feats, including surviving in extracellular matrix (ECM) detachment. ECM-detached cancer cells must evade a number of insults, including increased intracellular reactive oxygen species (ROS). Recent evidence suggests ECM-detached cancer cells rely on antioxidant enzymes to combat these increasing levels of ROS to promote survival; however, the specific antioxidant enzymes involved in this process have yet to be fully elucidated. Sestrin 2 (SESN2) is a multi-functional protein that has been found to be instrumental in many different signaling pathways; notably, it has been recognized to play a critical role in eliminating ROS. Here, we show that SESN2 plays a unique role in maintaining the viability of ECM-detached metastatic ovarian epithelial cancer cells, and elimination of this critical protein results in compromised viability. Thus, these data identify SESN2 as a potentially interesting therapeutic target for treating this deadly metastatic disease.
Smoothing Using Orthogonal Functions

In this chapter we will study an approach to nonparametric curve estimation based on orthogonal functions. We begin with a brief introduction to the theory of orthogonal functions, then we turn to density estimation and regression.
Effects of an H7 Highly Pathogenic and Related Low Pathogenic Avian Influenza Virus on Chicken Egg Production, Viability, and Virus Contamination of Egg Contents and Surfaces

Both highly pathogenic (HP) and low pathogenic (LP) avian influenza virus (AIV) can cause decreases or even cessation of egg production in chickens and turkeys. Production of abnormal eggs (deformed, thin-shelled, soft-shelled) can also be caused by AIV infection. Additionally, egg surfaces and contents may also be contaminated with virus. Because data quantifying these effects are lacking, white Plymouth Rock hens were inoculated with HP or LP AIV while in production. No decreases in egg production or abnormal eggs were observed with LPAIV-infected hens. No lesions or viral antigen staining in ovary and oviduct were observed in LPAIV-infected hens 3 days postchallenge. LPAIV RNA was detected on eggs collected from 12 hr to 11 days postinoculation (PI) and was on or in 6.4% (15/234) of the eggs. Titer equivalents of LPAIV ranged from 1.3-2.5 log10 50% egg infectious doses (EID50). No virus was detected in embryo tissue from eggs laid by LPAIV-infected hens. In contrast, egg production by HPAIV-inoculated hens decreased at 72 hr PI and 18.4% (16/87) of the eggs were abnormal. However, viability was similar to that of the sham inoculates. HPAIV RNA was detected in or on 11.1% (9/81) of the eggs from 36 hr through 96 hr PI, when the hens were euthanatized. HPAIV RNA was detected on 6.2% of eggshells, in 4.2% of albumin/yolk samples, and in 8.3% of embryo tissue. Forty percent of the abnormal eggs were positive for HPAIV RNA. Titer equivalents on or in HPAIV-contaminated eggs ranges from 1.0-4.0 log10 EID50. Lesions and viral antigen staining were present in the ovary and all sections of the oviduct of infected hens 3 days postchallenge. These data will inform models using production-based triggers for LPAIV monitoring and for risk assessments to determine the disposition of eggs from flocks infected with LPAIV or HPAIV.
Ruptured abdominal aortic aneurysm. Logistical and surgical considerations.

Summary o 1. From a total of nineteen cases of ruptured abdominal aortic aneurysm, a consecutive series of twelve cases has been subjected to review of various logistical and clinical features. 2. Two of the twelve patients failed to survive. Factors believed to be responsible for this mortality include delay in diagnosis, severely elevated blood pressure, and extension of the aneurysm above the renal arteries with a high rupture site. 3. Ten of twelve patients survived despite various degrees of shock, long transport distances, and advanced age. Factors contributing to survival include the avoidance of blood pressure elevation prior to operating room control and expediency of management.
Beyond Behaviorism: Engaging Students in the Age of Neoliberalism

Moving beyond behaviorism and neoliberalism in the classroom starts by recognizing how they have affected instructors and students in higher education. More specifically, this chapter describes how behaviorism affects both how instructors teach and how student learn. We take a closer look into how faculty members who do not move beyond behaviorism continue to be the holders of knowledge while students continue to regurgitate information without using inquiry, critical thinking, or problem-solving skills. This chapter seeks to discuss the importance of equity and social justice in higher education and how these two tenets are critical to the success of all students. Finally, this chapter provides applications of Engaged Pedagogy throughout, reinforcing why moving beyond behavioral-based teaching is not only warranted, but necessary to improve student engagement, performance, and experiences in higher education.
Efficient near-infrared luminescence from bis-cyclometalated iridium( iii ) complexes with rigid quinoline-derived ancillary ligands

Five new near-infrared (NIR) phosphorescent bis-cyclometalated iridium(iii) complexes, partnering highly conjugated cyclometalating ligands with quinoline-derived ancillary ligands, have been developed. These complexes have peak NIR luminescence wavelengths from 711 to 729 nm, with photoluminescence quantum yields ranging from 0.042 to 0.36.
Single-mode Er/Yb fiber MOPA at 1562nm with 302W power and 56% optical efficiency

We have demonstrated a new record of 302W single-mode power from an Er/Yb co-doped fiber master oscillator power amplifier (MOPA) with a record optical efficiency of 56%. This single-mode power is a new record for any lasers in this wavelength range. The previous record of single-mode power from an Er/Yb fiber laser pumped by a 9xx nm diode was 207 W at 1560 nm. The new optical efficiency of 56%, very close to the quantum-limited efficiency of 58.6%, is also a new record for Er/Yb fiber lasers. This new result is made possible mainly due to new fiber development from Nufern and off-resonant pumping of the Er/Yb fiber, which demonstrates further power-scaling potentials of Er/Yb fiber lasers pumped by widely available 9xx nm diodes. We also show that further power scaling is no longer limited by Yb3+ parasitic lasing near 1.06μm, but by fiber fuse in the Er/Yb fiber. The Yb3+ amplified spontaneous emission (ASE) was found to be negligible in all the cases we tested. Nonetheless, our numerical investigation shows that off-resonance pumping at 915 nm or 940 nm only plays a small role in the above-mentioned negligible ASE. We believe that the major cause may be the high Er3+ doping level in the Nufern Er/Yb co-doped fiber. Our results provide significant new insights and will stimulate further power scaling of Er/Yb fiber lasers and amplifiers.
Cannabinoids Decrease the K+ M-Current in Hippocampal CA1 Neurons

Cannabinoid effects on sustained conductances that control neuronal excitability have not been investigated in brain. Here, intracellular voltage-clamp recordings were performed using the rat hippocampal slice preparation to study the postsynaptic effect of cannabinoid agonists on CA1 pyramidal neurons. Superfusion of the cannabimimetics WIN55212–2 or methanandamide onto CA1 neurons elicited an inward steady-state current that reversed near the equilibrium potential for K+ and voltage-dependently activated from a threshold of approximately −70 mV. The cannabinoid receptor (CB1) antagonist SR141716 did not alter membrane properties but prevented this effect. Further investigation revealed that the inward current elicited by cannabinoids was caused by a decrease of the noninactivating voltage-dependent K+ M-current (IM). Cannabinoids had no effect in slices pretreated with the M-channel blocker linopirdine. Assessment of the IM relaxation indicated that cannabinoids decreased IM in a concentration-dependent manner, with a maximum inhibition of 45 ± 3% with WIN55212–2 (EC50 of 0.6 μm) and 41 ± 5% with methanandamide (EC50 of 1 μm). Cannabinoids did not affect the inwardly rectifying cationic h-current (Ih). The cannabinoid-induced IM decrease was prevented by SR141716 but remained unaffected by the muscarinic receptor antagonist atropine. Conversely, the cholinergic agonist carbamylcholine decreased IM in the presence of SR141716, indicating that cannabinoid and muscarinic receptor activation independently diminish IM. It is concluded that cannabinoids may postsynaptically augment the excitability of CA1 pyramidal neurons by specifically decreasing the persistent voltage-dependent IM.
tert‐Butyl Hypochlorite

tert-butyl hypochlorite product: tert-Butyl hypochlorite Keywords: halogenation, chlorination; tert-butyl hypochlorite, sensitive to light; flow meter; flow-rate-indicating fluid, (arochlors)
Clinical diagnosis of congenital heart murmurs by means of the symballophone

Summary The technique for the use of the symballophone in the differentiation of four of the common cardiovascular lesions has been described. These methods are of particular value in the study of congenital cardiovascular lesions.
Principles of Speculative Run-Time Parallelization

Current parallelizing compilers cannot identify a significant fraction of parallelizable loops because they have complex or statically insufficiently defined access patterns. We advocate a novel framework for the identification of parallel loops. It speculatively executes a loop as a doall and applies a fully parallel data dependence test to check for any unsatisfied data dependencies; if the test fails, then the loop is re-executed serially. We will present the principles of the design and implementation of a compiler that employs both run-time and static techniques to parallelize dynamic applications. Run-time optimizations always represent a tradeoff between a speculated potential benefit and a certain (sure) overhead that must be paid. We will introduce techniques that take advantage of classic compiler methods to reduce the cost of run-time optimization thus tilting the outcome of speculation in favor of significant performance gains. Experimental results from the PERFECT, SPEC and NCSA Benchmark suites show that these techniques yield speedups not obtainable by any other known method.
Concept and analytical basis for revistas - A fast, flexible computer/graphic system for generating periodic satellite coverage patterns

The generation of satellite coverage patterns is facilitated by three basic strategies: use of a simplified physical model, permitting rapid closed-form calculation; separation of earth rotation and nodal precession from initial geometric analyses; and use of symmetries to construct traces of indefinite length by repetitive transposition of basic one-quadrant elements. The complete coverage patterns generated consist of a basic nadir trace plus a number of associated off-nadir traces, one for each sensor swath edge to be delineated. Each trace is generated by transposing one or two of the basic quadrant elements into a circle on a nonrotating earth model sphere, after which the circle is expanded into the actual 'helical' pattern by adding rotational displacements to the longitude coordinates. The procedure adapts to the important periodic coverage cases by direct insertion of the characteristic integers N and R (days and orbital revolutions, respectively, per coverage period).
The pelagic distribution of marine birds in a heterogeneous environment

In this paper I review recent, small-scale, process-oriented studies of the pelagic distribution of marine birds. I examine the roles played by a variety of hydrographic features, including steep flow gradients (fronts) and water column stratification, in determining the abundance or availability of avian prey. The ice edge/marginal ice zone is a frontal area of particular interest in polar regions. In most oceanic systems we have examples of avian use of a feature, hut only poor information on the importance of the feature for supporting the population as a whole. I review recent studies of the spatial and numerical concordance of marine birds and their prey, and find that these studies have yielded mixed results, with correlations stronger for piscivorous birds, particularly murres foraging on capelin, than for planktivores. Review of investigations of multispecies interactions during foraging shows that flock foraging has both beneficial and negative aspects. Interspecific facilitation of foraging occurs in numerous interactions involving both other species of birds and marine mammals. However, co-occurrence of predators may occur because both seek the same prey, and caution must be used in assessing mutualistic interactions between predatory species.
Pointwise fourier inversion and related eigenfunction expansions

Necessary and sufficient conditions are found for the convergence at a pre-assigned point of the spherical partial sums (resp. integrals) of the Fourier series (resp. integral) in the class of piecewise smooth functions on Euclidean space. These results carry over unchanged to spherical harmonic expansions, Fourier transforms on hyperbolic space, and Dirichlet eigenfunction expansions with respect to the Laplace operator on a class of Riemannian manifolds. © 1994 John Wiley & Sons, Inc.
Catheter-related deep venous thrombosis in children with hemophilia

Central venous catheters (CVCs) are a common adjunct to hemophilia therapy, but the risk of CVC-related deep venous thrombosis (DVT) in hemophiliacs is not well defined. In a previous study, 13 patients with CVCs had no radiographic evidence of DVT. However, recent abstracts and case studies demonstrate that DVT does occur. Therefore, this study sought to determine the frequency of DVT in children with hemophilia and long-term CVCs and to correlate venographic findings with clinical features. All hemophilia patients with tunneled subclavian CVCs in place for 12 months or more were candidates for evaluation. Patients were examined for physical signs of DVT and questioned about catheter dysfunction. Contrast venograms were obtained to identify DVT. Fifteen boys with severe hemophilia were evaluated, including 9 from the initially studied group of 13. Eight patients had evidence of DVT, 5 of whom previously had normal venograms. Five of 15 patients had clinical problems related to the CVC, all of whom had DVT. Four of 15 patients had suggestive physical signs; 3 had DVT. The mean duration of catheter placement for all patients was 57.5 months (range, 12-102 months). For patients with DVT, the mean duration was 66.6 +/- 7.5 months, compared to 49.5 +/- 7.2 months for patients without DVT (P =.06). No patient whose CVC was in place fewer than 48 months had an abnormal venogram. Many hemophilia patients with CVCs develop DVT of the upper venous system, and the risk increases with duration of catheter placement.
Wholesalers as Global Marketers

ABSTRACT The notion of wholesalers as global marketers is almost an oxymoron in marketing thought. Yet, in fact, wholesalers as an institutional type have for thousands of years been involved in what today we refer to as global marketing. Wholesalers of many types have performed numerous activities or functions that have always been necessary for connecting distant buyers and sellers so that transactions can be consummated across international boundaries. In fact, by performing many distribution tasks or functions, wholesaling intermediaries of all types create the channel flows that link buyers and sellers together on a global scale. These flows, of which there are eight (product, ownership, promotion, negotiation, financing, risking, ordering, and payment), do not automatically appear out of thin air. Rather, the eight flows are created and sustained by many types of organizations that perform all of the myriad distribution tasks needed to connect sellers and buyers. Wholesale distributive institutions ...
Evaluation of Industrial Hearing Conservation Programs: a Review and Analysis

In 1981, a large scale review of the literature concerning the effects of noise on hearing was initiated by the National Institute of Neurological and Communicative Diseases and Stroke. This review concentrated on the information published in the decade of the 1970's and underscored the importance of evaluating the effectiveness of industrial hearing conservation programs. Published information on this topic was scanty prior to 1970. Investigations of the application and utility of methods for this evaluation have only recently begun to appear in the literature. The status of evaluating hearing conservation programs is the subject of the present review. Three evaluation methods are considered in detail: use of various proposed criteria for significant threshold shift; methods used by Pell at DuPont; and more recent methods developed by Royster. The condition and availability of data do not permit selection of the optimum evaluation procedure. Systematic collection and analysis of data from industrial prog...
Great Lakes research – Important human health findings and their impact on ATSDR's Superfund research program

The Agency for Toxic Substances and Disease Registry (ATSDR) was created by the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) of 1980, commonly known as Superfund. ATSDR is the principal United States federal public health agency involved with issues of public health and applied science concerning the human health impact of living in the vicinity of a hazardous waste site, or emergencies resulting from unplanned releases of hazardous substances into community environments. In pursuing these mandates, ATSDR's mission is to prevent exposure and adverse human health effects and diminished quality of life associated with exposure to hazardous substances from waste sites, unplanned releases, and other sources of pollution present in the environment. There are more than 2,000 toxic substances found at hazardous waste sites in the United States. ATSDR has developed a prioritized list of 275 substances that pose the greatest hazard to human health. In conducting its work ATSDR has identified data gaps in knowledge about the toxicity of various hazardous substances as well as gaps in human exposure characterization. As part of its mandate, ATSDR initiated a Substance-Specific Applied Research Program (SSARP) to address these data gaps. The ATSDR Great Lakes Human Health Effects Research Program (GLHHERP) is a congressionally-mandated research program that characterizes exposure to persistent toxic substances and investigates the potential for adverse health outcome in at-risk populations. The research findings from this program in the areas of exposure, sociodemographic data, and health effects have significant public health implications for ATSDR's Superfund research activities.
Validation of criteria for psychiatric hospitalization checklist

In a retrospective study, an attempt was made to assess the utility of a 12-item psychiatric hospitalization checklist. Significantly higher scores were obtained from a hospitalized as opposed to an outpatient sample. Patients who obtained higher scores on this checklist also exhibited significantly greater psychopathology as measured by the MMPI. The assets and liabilities of the checklist are discussed.
Low Prevalence of Influenza Vaccination Among People with Cardiovascular Disease—BRFSS

Background People with cardiovascular disease are at high risk of complication from influenza. However, little is known about influenza vaccine coverage among this population. Methods Using 2002 Behavioral Risk Factor Surveillance System data, the authors studied the prevalence of influenza vaccination in the previous 12 months among participants aged ≥18 years with cardiovascular disease or hypertension. Results After adjustment for age, gender, race/ethnicity, and education, the prevalence of influenza vaccination ranged from 35.9% to 42.6%. The prevalence was particularly low among participants with cardiovascular disease aged 18–49 years (range, 23.9% to 42.2%). The prevalence of influenza vaccination varied considerably between states among people with hypertension (range, from 30.2% to 45.9%) and those with other cardiovascular diseases (range, from 37.0% to 51.5%). Conclusions Influenza vaccination levels are low among people with cardiovascular disease, especially those less than 50 years old. They should be encouraged to receive an annual influenza vaccination to avoid cardiovascular complications from influenza.