cssi/SciSciGPT-SciSciNet huggingface dataset:
Changes in peripheral circulation in lower extremities following the Beck I operation for coronary heart disease.

HIS study was done because many patients stated that their feet were warmer after the Beck I operation for coronary heart disease.l Warming of the feet, if it occurred, would indicate a significant change in the peripheral circulation. This study was designed to document any such changes in these patients. One of the first references to a relationship between coronary heart disease and skin temperatures was made by Doret and Ferrero2 in 1951. These authors showed that the temperature was reduced over the areas of angina1 pain radiation compared to temperatures elsewhere. Van Herbert3 confirmed these observations and also showed that the temperatures rose over the area of pain radiation after cessation of pain. Hardy and Soderstrom4 recorded skin temperatures in normal patients and found that under basal conditions, the average skin temperature of the foot was 31°C and of the lower leg, 33’. Stewart and Evans? showed that the basal metabolic rate and arterial blood pressure had no effect upon skin temperatures of the foot. The true significance of skin temperatures
Optimal bayes joint decision and estimation

Many problems involve joint decision and estimation, where qualities of decision and estimation affect each other. This paper proposes an integrated approach based on a new Bayes risk, which is a generalization of those for decision and estimation separately. Theoretical results of the optimal joint decision and estimation that minimizes the new Bayes risk are presented. The power of the new approach is illustrated by applications in target tracking and classification.
Coordinate-interleaved space-time coding with rotated constellation

This paper proposes a combined method of coordinate-interleaved space-time coding and rotated constellation, also known as signal-space diversity. The merits of space-time transmit diversity are supplemented with constellation rotation, which provides another way of providing diversity. Without any loss in the advantages of each source of diversity, the diversity order can be increased by up to twice the order of space-time coding or signal-space diversity. The combination of these two diversity schemes provides complementary effects to combat fast-varying and slowly-varying channel fading.
Characteristics and Applications of Precise GPS Clock Solutions Every 30 Seconds

Using carrier phase and pseudorange data from a small network of globally distributed GPS receivers with precise time references, we are able to estimate GPS clock parameters every 30 s, with subdecimeter accuracy, in a computationally efficient manner. The accuracy obtained is a factor of 100 to 1000 times better than that of clocks in the broadcast navigation message, and allows postprocessing of high-rate single-receiver kinematic GPS data with few-centimeter-level precision when used in conjunction with precise GPS orbits. The amplitude of the daily clock variability is typically 24 m for satellites affected by Selective Availability (SA). Temporal variations are well modeled by an autocorrelation function p = exp(-d 2 /2τ 2 ) with τ = 106 s.
Offensive Motivation Strategies: The Managerial And Legal Implications

This case study focuses on corporate culture, ethics, employment law, and motivation theory and is appropriate for use in a variety of management classes, such as organizational behavior, human resource management, or ethics. It profiles a lawsuit brought against a company by one of its female employees who was subjected to a variety of “camaraderie building” exercises, including being spanked with a competitor’s metal poled yard sign. The case is based on a true story. Only the names and locations have been changed. This case includes actual descriptions of company practices and communications which are offensive and may be disturbing. However, they have been included so that the reader can appreciate the severity of the “motivational practices” that were being employed.
Cloud-Top Heights from GOES-8 and GOES-9 Stereoscopic Imagery

Abstract Operational satellite data from GOES-8 and GOES-9 were used to make stereoscopic measurements of cloud heights during the National Aeronautics and Space Administration’s Subsonic Aircraft: Contrail and Cloud Effects Special Study program. The stereoscopic data were used to differentiate between boundary layer wave clouds and cirrus in the mid- and upper troposphere. This separation was difficult to evaluate from radiometric data alone. Stereographic cloud height analysis provided a definitive result. The technique used for calculating cloud heights is described. GOES-8 and -9 data were better suited for stereoscopic measurements than data from previous satellites.
Predation of Stink Bugs (Hemiptera: Pentatomidae) by a Complex of Predators in Cotton and Adjoining Soybean Habitats in Georgia, USA

Stink bugs (Hemiptera: Pentatomidae) are economic pests of cotton and soybean. This study was conducted to examine predation on stink bugs by arthropod predators in cotton and adjoining soybean habitats. Gut-content analysis based on polymerase chain reaction (PCR) was used to detect stink bug deoxyribonucleic acid (DNA) in predators collected from both crops over a 5 wk period. Nezara viridula (L.), Euschistus servus (Say), Chinavia hilaris (Say), and Euschistus quadrator Rolston were detected on soybean and cotton. Piezodorus guildinii (Westwood) and Thyanta custator custator (F.) were detected only on soybean whereas Euschistus tristigmus (Say) was detected only on cotton. Over both crops, 13 predators screened positive for a variety of stink bug species DNA by PCR analysis: Geocoris punctipes (Say) and Geocoris uliginosus (Say) (Hemiptera: Geocoridae), Orius insidiosus (Say) (Hemiptera: Anthocoridae), Hippodamia convergens Guerin-Meneville, Harmonia axyridis (Pallas) (cotton), and Scymnus sp. (cotton) (Coleop tera: Coccinellidae), Oxyopes salticus Hentz and Peucetia viridans (Hentz) (cotton) (Araneae: Oxyopidae), Solenopsis invicta Buren (Hymenoptera: Formicidae), Podisus maculiventris (Say) (Hemiptera: Pentatomidae), Mecaphesa asperata (Hentz) (Araneae: Thomisidae), Zelus renardii Kolenati (Hemiptera: Reduviidae), and Notoxus monodon (F.) (cotton) (Coleoptera: Anthicidae). In soybean, the percentage of G. punctipes and G. uliginosus screening positive for N. viridula was high, 87.3%, whereas the percentage screening positive for E. servus was moderately high, 60.3%. In cotton, the percentage of N. viridula DNA in gut-contents of O. insidiosus was high, 91.6%. Detection of P. guildinii and/or T. c. custator DNA in predators in cotton and of E. tristigmus DNA in predators in soybean demonstrated predator dispersal between soybean and cotton. In soybean, the percentage of P. guildinii DNA in gut contents of G. punctipes, G. uliginosus, and O. insidiosus, including those individuals in cotton that dispersed from soybean, was high. We conclude that a complex of arthropod predators prey on a complex of stink bugs in both cotton and adjoining soybean while foraging in and between these crops.
Empirical Research on Employment Arbitration: Clarity Amidst the Sound and Fury

This article reviews the existing empirical research on employment arbitration and presents new findings based on analysis of data from recent American Arbitration Association employment arbitration case filings. Whereas past research often concluded based on more limited datasets that outcomes from employment arbitration were generally similar to those from litigation, results of the present study, which is based on a larger dataset focused on cases involving employer promulgated agreements, indicate that both employee win rates and damage awards in employment arbitration are significantly lower than in litigation. By contrast, results of the present study confirm previous research findings that time to hearing is generally shorter in employment arbitration than in litigation. As with past research, the present study finds evidence of a repeat player effect, though with some uncertainty as to the causal explanation for this effect. Self-representation of employees is found to be associated with significantly worse employee win rates and damage awards, particularly where the case involves by a repeat employer-arbitrator pairing. Lastly, the article reviews research indicating some positive impacts of employment arbitration on the adoption and operation of internal organizational dispute resolution procedures.
14% CdS/CdTe Thin Film Cells with ZnO:Al TCO

An Al-doped ZnO front contact was successfully used for the first time for the fabrication of high efficiency CdS/CdTe thin-film solar cells. The ZnO:Al films were deposited on aluminosilicate glass by RF sputtering from a ZnO:Al2O3 target. The ZnO:Al film has ∼95% average transmission in the visible spectrum with ∼3 ohm/square sheet resistance. The CdS and CdTe thin films were also deposited by RF sputtering and devices were completed with a vapor CdCl2 treatment and evaporated Cu/Au back contacts. The highest processing temperature was 387°C, reached during the vapor CdCl2 treatment. The devices were tested at NREL with efficiency of 14.0% which is a record for an all-sputtered CdS/CdTe solar cell. The ZnO-based cell had JSC of 23.6 mA/cm2 compared to 20.7 mA/cm2 for our recent NREL-tested 12.6% cell on a commercial soda-lime-glass/SnO2:F substrate. Other parameters of the 14% ZnO based cell are: FF = 73.25% and VOC = 814 mV. The improved performance is almost entirely due to higher current because of better optical and electrical properties of ZnO:Al TCO. We report also on relative stability between devices on SnO2:F and ZnO:Al TCO, under one-sun light soak at VOC.
Outcomes of living kidney donors with medullary sponge kidney

Background Patients with medullary sponge kidney (MSK) commonly encounter recurrent nephrolithiasis. The existing knowledge on safety of donors with MSK has not been studied. Methods We conducted a retrospective cohort study at a tertiary referral hospital to assess the outcomes of living kidney donors with MSK. All adults with MSK (N = 26) who underwent nephrectomy as living kidney donors between January 2000 and September 2014 were included. Non-donors with MSK (N = 78) were randomly selected by matching the year of birth and the comorbidity score with a ratio of 1:3 for comparison. Results The incident rates of symptomatic stone were 0.7, 0.4 and 4.9 events/100 patient-years in donors, recipients and non-donors, respectively. After adjusting for history of kidney stones and baseline estimated glomerular filtration rate (eGFR), the kidney stone-related event was significantly lower in donors than in non-donors (hazard ratio 0.14; 95% confidence interval 0.01-0.66). One recipient of MSK living donor had symptomatic stone at median follow-up time of 8.4 years (interquartile range 5.6-12.4 years). None of MSK donors had hypercalciuria, hypocitraturia or hyperoxaluria prior to kidney donation. At 5 years after the index surgery date, there was no significant difference in eGFR between donors and non-donors (76.1 versus 70.9 mL/min/1.73 m2, P = 0.12). Conclusions These findings are reassuring for the safety of MSK kidney donors with normal kidney function, low kidney stone risk and no significant comorbidity.
Color and Height Preference of the Citrus Thrips in a Navel Orange Grove

When white, yellow, blue, red, green, and black sticky traps were used to capture Scirtothrips citri (Moulton) on navel orange trees at Riverside, California, the white traps captured the significantly greater numbers. Also, activity was significantly greater on the southeast quadrant of the tree, and a significantly greater number was found 2.7 m aboveground. Other species of Thysanoptera captured included Frankliniella occidentalis (Pergande), F. minuta (Moulton), Thrips tabaci Lindeman, Scolothrips pallidus (Beach), Bregmatothrips sonorensis Stannard, and Isoneurothrips australis Bagnall.
Ideological Origin of Sun Tzu's Estimates

From the angle of the inheritation and innovation of Chinese traditional culture,this article retrospects to the theoretical origin of Sun Tzu's estimates and expounds the logic relationship among the theory of estimates and Eight Trigrams and Zhou Yi.Through the comparison,this article expounds the theoretical attribution of Sun Tzu's estimates system,the scientific connotation of the elements of estimates and the ancients' historic development from divination to estimates.Therefore,the historical position and significance of the times of Sun Tzu's estimates thinking is further exposed.
387 cAMP RESPONSE ELEMENT BINDING PROTEIN AND COLLAGEN 1 IMPACT ON VASCULAR SMOOTH MUSCLE CELL GENE REGULATION AND PHENOTYPE

Atherosclerosis is a major cause of morbidity and mortality in the U.S. In response to vascular injury, vascular smooth muscle cells (VSMC) undergo phenotypic modulation, a switch in phenotype from quiescent to active (proliferative, migratory and pro-apoptotic). Phenotypic modulation or de-differentiation of VSMC may play an important role in atherosclerotic plaque instability. Structural matrix proteins affect VSMC phenotype, but little is known about the mechanism of this effect. To better understand the impact of matrix protein on VSMC phenotype we cultivated VSMC on native Type 1 collagen fibrils (NC) or denatured collagen (DNC). Adult VSMC showed dramatic alterations in morphology from the flat, lamellar morphology of cells plated on DNC to stellate shaped cells with multiple dendritic processes on NC. We hypothesized that NC was leading to an activated VSMC phenotype by decreasing expression of key transcriptional regulators of VSMC differentiation. Our group has established that the transcriptional regulator CREB (cAMP response element binding protein) plays a key role in the maintenance of the quiescent, differentiated SMC phenotype. Other markers of VSMC differentiation are smooth muscle a-actin (SMA) and Serum Response Factor (SRF). SMA, CREB and SRF are highly expressed in quiescent cells and expressed at low levels in proliferative cells. VSMC plated on NC for 24 or 48 hours had significant decreases in SMA, CREB and SRF protein expression. The decrease in SMA involved transcriptional control, as there was also a significant reduction in SMA promoter activity. We investigated the mechanisms involved in the decreased SMA and CREB expression of adult cells on NC. Growth of adult VSMC on NC resulted in increased activation of the PI3kinase signaling cascade and AKT as compared to cells on DNC. Pharmacological disruption of AKT signaling blocked NC downregulation of SMA and CREB. We next assessed the relationship between vascular collagen 1 expression, CREB, and SRF protein content in vivo. Aortic lysates from lean and fatty Zucker rats were examined for collagen 1, CREB and SRF by Western Analysis. Collagen 1 expression increased in the fatty rats by 200% between 4-14 weeks, CREB content decreased to 60% of baseline and SRF protein decreased to 20% of baseline. Summary Collagen 1 exposure correlates with VSMC dedifferentiation in vivo and in vitro. Vascular collagen accumulation may promote atherosclerosis. Funding Source: DK19928, DK064741
Human papillomavirus deoxyribonucleic acid and ribonucleic acid in seminal plasma and sperm cells

Objective To investigate the possible presence and expression of human papillomavirus viruses (HPV) in human seminal plasma and sperm cells. Design Controlled clinical study. Setting A major medical center affiliated with a medical college. Patients Twenty-four randomly selected patients who attended Fertility Clinics at the Chang Gung Memorial Hospital. Interventions Specimens of semen were collected from volunteered patients. Main Outcome Measure The presence of HPV types 16 and 18 DNA and RNA sequences were examined by polymerase chain reaction. Results Human papillomavirus type 16 E6 and E7 DNA and RNA sequences were found in two and zero seminal plasma specimens, respectively, and in six and two sperm cells specimens, respectively. Deoxyribonucleic acid and RNA sequences of HPV type 18 were found in eight and two seminal specimens and in 11 and 5 sperm cells specimens, respectively. Conclusion These results seem to suggest that HPV cannot only infect human sperm cells, certain HPV genes are expressed actively in infected sperm cells. The virus-infected sperm cells conceivably can behave as vectors or carriers for the transmission of HPV, to sexual partner during sexual contact, to fetuses through fertilized eggs, or both.
Methods for Adenovirus-Mediated Gene Transfer to Synovium In Vivo

The synovial membrane that lines diarthrodial joints is composed of a loose layer of cells (1-4 cells in depth) that overlie the surface of articular and periarticular subsynovial tissues including connective tissue, adipose tissue, tendon, bone, and articular cartilage. Using light microscopy, the synovial lining tissue appears discontinuous and lacks a clearly defined basement membrane, although the cells appear to be retained by a reticulum. Cells present below this membrane include mast cells and endothelial cells (up to 10% of the total cell population; refs. 1,2). Ultrastructural studies of the synovium have indicated that at least two major types of cells are present within the synovial membrane. Type A cells are monocytoid in appearance and contain abundant endoplasmic reticulum with fewer vesicles, vacuoles, and mitochondria. Type B cells are fibroblastoid in appearance and contain large granules, numerous filopodia, mitochondria, and intracellular vesicles. The percentage of Type A and B cells present within adult synovium varies between species (3-5). In addition, cells with an intermediate ultrastructural appearance and morphology may exist within adult synovium (6).
Stimulation of chloride transport by cAMP in rat proximal tubules

We have previously demonstrated that formate and oxalate stimulate transcellular Cl- absorption (JCl) in the rat proximal tubule by a mechanism involving DIDS-sensitive anion exchange across the luminal membrane and diphenylamine-2-carboxylate (DPC)-sensitive Cl- channels in the basolateral membrane. Recent evidence indicates cAMP activation of Cl- channels in apical and basolateral membranes of proximal tubule cells. We therefore tested the effect of cAMP on Cl- and fluid transport in rat proximal tubule studied by luminal and capillary microperfusion in situ. The luminal perfusate contained 5 mM HCO3- and 145 mM Cl-, and the capillary perfusate contained 25 mM HCO3- and 110 mM Cl-, simulating conditions in the late proximal tubule. Addition of 0.5 mM dibutyryl cAMP markedly stimulated fluid absorption (Jv) and JCl. Similar effects resulted from addition of forskolin (10 microM) to stimulate cAMP production. The increments in Jv and JCl due to dibutyryl cAMP were abolished when the Cl- channel blocker DPC (200 microM) was added to the capillary perfusate but not when it was added to the lumen. The increments in Jv and JCl due to dibutyryl cAMP were unaffected by luminal DIDS (100 microM), which abolishes the increments in Jv and JCl induced by addition of oxalate. In contrast, the increments in Jv and JCl due to dibutyryl cAMP were abolished by luminal 5-nitro-2-(3-phenylpropylamino)benzoate (NPPB; 10 microM), another Cl- channel blocker. Luminal NPPB had no effect on baseline Jv and JCl nor on the increments in Jv and JCl induced by addition of oxalate.(ABSTRACT TRUNCATED AT 250 WORDS)
The Effects of Rapport-Building Strategies in the Online Political Science Classroom

As the prevalence of online education continues to grow, so do concerns about student success. Students in online classes tend to withdraw more often and earn lower grades, compared to in-person classes. Some explanations for this disparity point to student characteristics, while others point to things instructors can do to facilitate greater success. I hypothesize that the difficulty of establishing rapport in an online classroom makes it easier for students to forget about, not prioritize, or not feel as great of a responsibility toward, their online classes. Thus, improving rapport with online students may lead to improvements in student success. To test this hypothesis, I implemented rapport-building teaching strategies — including video updates, personal emails, handwritten electronic comments on assignments, and office hours via Skype — in two online classes (student n=51) and compared student outcomes in those classes to online classes taught without these measures (student n=324). The data indicate that rapport-building strategies do not have a significant impact on student grades or retention rates. They do, however, significantly affect the students’ views of the instructor and may hold other potential future benefits as well.
Temperature and hydrostatic pressure-dependent pathways of low-density lipoprotein transport across microvascular barrier

To further investigate the chemical and physical nature of low-density lipoprotein (LDL) transport pathways across intact microvessels, the effect of changes in temperature and microvessel hydrosta...
CR Based Video Communication Testbed with Robust Spectrum Sensing / Handoff

As radio spectrum is becoming congested, wireless communications require more efficient spectrum usage. Recently, the cognitive radio (CR) techniques have become attractive as they can utilize any unused spectrum. In this paper, we build a CR video communication test-bed, which implements spectrum sensing and spectrum handoff functionalities in USRP boards. We have implemented compressive spectrum sensing, intelligent spectrum handoff, multi-video-flow transmission, under TDMA scheduling and Raptor codes for reliable video transmissions. By using compressive sensing in spectrum sensing method, the spectrum detection accuracy is improved without much algorithm complexity, and it is also robust to the noise uncertainty due to the use of cyclostationary features. To realize intelligent spectrum handoff, we have designed a real-time jamming detection scheme, as well as synchronized spectrum switching method. We have also implemented a multi-point TDMA-based communication system, which enables any node to send out multiple video flows to different neighbors with pipelined and scheduled data transmissions. We also proposed a special rateless codes called prioritized Raptor codes for more reliable video transmission and implemented in the GNU Radio applications. The proposed CR video transmission testbed can be used for new protocol testing purpose.
Radiation Exposure by Three-Dimensional Rotational Angiography (3DRA) During Trans-catheter Melody Pulmonary Valve Procedures (TMPV) in a Pediatric Cardiac Catheterization Laboratory

This retrospective study aims to evaluate radiation exposure by three-dimensional rotational angiography (3DRA) during trans-catheter Melody pulmonary valve (TMPV) procedures. 3DRA has been reported to have added value in the management of complex congenital heart disease aiding in the performance of interventional procedures albeit with concerns of higher radiation exposure. We test the hypothesis that 3DRA does not cause additional radiation exposure during TMPV procedures. We analyzed all 81 TMPV procedures performed at St. Louis Children’s Hospital, MO, USA, from January 1, 2011 to December 31, 2014. Dose-area product (DAP), DAP indexed to body weight (DAP/BW), fluoroscopy time (FT), and weight–fluoroscopy time product of each procedure were recorded. We reviewed each procedure’s images to determine whether additional interventions were performed (e.g., pulmonary artery angioplasty or treatment of conduit pseudo-aneurysm). 3DRA was used in 36 % of the procedures. 3DRA group had a higher number of additional procedures performed. The 3DRA group did not differ from the non-3DRA group in DAP, DAP/BW, and weight–fluoroscopy time product. 3DRA does not cause greater radiation exposure during TMPV procedures.
Huygens–Fresnel wavefront tracing

Abstract We present initial results from a novel numerical method describing wave propagation in slowly non-uniform media. Following Huygens–Fresnel’s principle, we model the wavefront as an array of point sources that emit wavelets, which interfere. We then identify a set of new points where the electric field has equal phase. In fact, without losing generality, we find zeros of the electric field, by means of the bisection method. This obviously corresponds to a specific phase-advance, but is easily generalized, e.g. by phase-shifting all sources. The points found form the new wavefront, then the process is reiterated. One of the advantages of the method is that it includes diffraction. Two examples provided are diffraction around an obstacle and the finite waist of a focused Gaussian beam. Refraction is also successfully modeled, both in slowly-varying media as well as in the presence of discontinuities. The calculations were performed in two dimensions, but can be easily extended to three dimensions. We also discuss the extension to anisotropic, birefringent, absorbing media.
Typing and semantics of asynchronous arrows in JavaScript

Asynchronous programs in JavaScript using callbacks and promises are difficult to write correctly. Many programs have subtle errors due to the unwanted interaction of event handlers. To fix such errors, the programmer is burdened with explicit registration and de-registration of event handlers. This produces fragile code which is difficult to read and maintain.Arrows, a generalization of monads, are an elegant solution to asynchronous program composition. In this paper, we present the semantics of an arrow-based DSL in JavaScript which can encode asynchronous programs as a state machine where edge transitions are triggered by external events. To ensure that arrows are composed correctly, we provide an optional type checker that reports errors before the machine begins execution.
Giant Reverse Transcriptase-Encoding Transposable Elements at Telomeres

Transposable elements are omnipresent in eukaryotic genomes and have a profound impact on chromosome structure, function and evolution. Their structural and functional diversity is thought to be reasonably well-understood, especially in retroelements, which transpose via an RNA intermediate copied into cDNA by the element-encoded reverse transcriptase, and are characterized by a compact structure. Here, we report a novel type of expandable eukaryotic retroelements, which we call Terminons. These elements can attach to G-rich telomeric repeat overhangs at the chromosome ends, in a process apparently facilitated by complementary C-rich repeats at the 3'-end of the RNA template immediately adjacent to a hammerhead ribozyme motif. Terminon units, which can exceed 40 kb in length, display an unusually complex and diverse structure, and can form very long chains, with host genes often captured between units. As the principal polymerizing component, Terminons contain Athena reverse transcriptases previously described in bdelloid rotifers and belonging to the enigmatic group of Penelope-like elements, but can additionally accumulate multiple cooriented ORFs, including DEDDy 3'-exonucleases, GDSL esterases/lipases, GIY-YIG-like endonucleases, rolling-circle replication initiator (Rep) proteins, and putatively structural ORFs with coiled-coil motifs and transmembrane domains. The extraordinary length and complexity of Terminons and the high degree of interfamily variability in their ORF content challenge the current views on the structural organization of eukaryotic retroelements, and highlight their possible connections with the viral world and the implications for the elevated frequency of gene transfer.
Comparing Allinea's and Intel's performance tools for HPC

To efficiently use HPC machines, it is critical to optimize applications for high performance. To accomplish this, HPC developers must utilize performance tools to find and correct performance problems within large, complex scientific applications. Allinea and Intel offer vendor-supported performance tools that are regularly updated to capture important performance metrics on the latest hardware. In this paper, the authors evaluated and compared Allinea's MAP performance tool and Intel's performance tools to aid in application optimization. The authors found that Allinea's MAP provided useful performance metrics necessary to diagnose and fix performance problems using an intuitive, easy-to-use user interface. Intel's performance tools provided a more detailed and customizable view of application performance, at the expense of a more complicated user interface. The comparison presented in this paper will help HPC developers decide which performance tool is best for them.
Firm Resource Position, Resource Complementarity, and the Heterogeneity in Resource Value

Although what determines the value of resources is the central question in the resource-based view (RBV), both widely accepted answers to this question and empirical research testing it are lacking...
First Report of the Genus Telamoptilia from the Western Hemisphere with Descriptions of Two New Species (Gracillariidae)

ABSTRACT. The genus Telamoptilia (Acrocercopinae) is reported from the Western Hemisphere for the first time. Two new species, Telamoptilia hibiscivora, from the eastern United States, and T. pavoniae , from western Cuba, are described and illustrated. The larvae initially begin as serpentine leafminers and eventually form mostly full depth blotch leafmines on Malvaceae. Telamoptilia hibiscivora mines the leaves of Hibiscus moscheutos L. and the lavae of T. pavoniae mine Pavonia fructicosa (Mill.), Malvaceae.
Template-free synthesis of highly selective amorphous aluminosilicate catalyst for toluene alkylation

Abstract In this paper, we report a simple template-free synthetic method that produces amorphous, nanoporous aluminosilicate and highly selective catalyst for toluene alkylation. The structure and composition of the material and its corresponding control material are characterized by various techniques. The material shows excellent catalytic selectivity for alkylation of toluene by tert-butyl alcohol in temperatures between 50–150 °C under atmospheric pressure, producing exclusively 4-tert-butlytoluene (ca. 99%).
Communicating Across Diverse and Differently Literate Audiences

Oncologists and fertility specialists are often challenged when communicating to patients the complex information about cancer, risks of cancer treatment to reproduction, and the processes of fertility preservation (FP), including the probabilities for successful later conception. This has added to the already unfair burden of cancer upon certain populations of women who may have limited backgrounds or levels of literacy. A small but growing number of professionals and organizations are steadily improving access to fertility preservation information for such women. The following discussion outlines the communication barriers and presents strategies for clinicians to improve the dissemination of fertility preservation information to patients.
PREVENTION OF ELDERLY SUICIDE : PHYSICIANS' ASSESSMENT OF FIREARM AVAILABILITY

Abstract Introduction: Physicians have a unique role to play in the prevention of elder suicide, yet they may not be sufficiently attentive to the prominence of firearms in the rising trend in suicide by elderly persons. This study sought to examine the extent to which physicians inquired about firearms with their depressed and suicidal elderly patients and further identified factors associated with physicians’ likelihood of asking about firearms. Methods: A probability sample of 300 primary care physicians in Illinois was drawn from the American Medical Association Physician Masterfile. Physicians were chosen from the specialties most likely to be involved with elderly persons: internal medicine and family practice. A mailed questionnaire yielded a 63% response rate. Results: Although they were treating depressed and suicidal older patients, a sizable proportion of the respondents (42%) reported that they did not ask such patients or their family members whether they had access to a firearm. Several factors distinguished physicians who assessed for firearms from those who did not. The most salient predictors were: continuing medical education training in suicide risk assessment, expertise in geriatric mental health, confidence in diagnosing depression, having a patient mention suicide in the past year, and indicating patient reluctance as a barrier to mental health treatment. Discussion: Physicians working with depressed and suicidal elderly persons need to be informed about the prevalence of elder suicide and about the likelihood of elderly persons using firearms as a method of suicide. Effective suicide prevention will require physician training that directly addresses geriatric mental health and firearm suicide, in particular, at the student, residency, and continuing education levels.
Neurocognitive dysfunction in adult cerebellar medulloblastoma.

Objective Impaired neurocognitive function (NCF) is a well-established consequence of pediatric medulloblastoma (MB) and its treatments. However, the frequency and features of neurocognitive dysfunction in adult-onset MB patients are largely unknown. Methods Adult patients (≥ 18 years) with MB who had received formal neurocognitive evaluation (N = 27) were identified. Demographic, medical, and treatment histories were extracted from the medical record. Lesion properties on MRI were analyzed and used to evaluate lesion-symptom mapping further. Demographically adjusted z-scores were calculated for each neurocognitive test and used to assess impairment frequency. Regression analyses were conducted to identify clinical and paraclinical factors associated with impaired NCF. Results Mean age of the patient sample was 33 years (SD = 11) at the time of MB diagnosis. Prior therapy included surgical resection (89%), radiation (70%), and chemotherapy (26%). A significant proportion of patients were impaired on tests of verbal learning and memory (32%), executive function (29%), and naming (18%). Age, education, lesion size, time from surgery, and number of chemotherapy cycles had the greatest contribution to test performance in random-forest regression models. Conclusion This study identifies frequent impairment of NCF in adult patients with MB, particularly in the domains of learning and memory and executive function. Neurocognitive impairment is influenced by patients' demographic, disease, and treatment history. Further study is warranted to characterize the clinical impact of adult MB more fully.
DeepCoast: Quantifying Seagrass Distribution in Coastal Water Through Deep Capsule Networks

Seagrass is a highly valuable component of coastal ecosystems ecologically and economically, yet reliable mapping of seagrass density is not available due to the high cost of data processing and spatial mapping. This paper presents a deep learning approach for quantification of leaf area index (LAI) levels of seagrass in coastal water using high resolution multispectral satellite images. Specifically, a deep capsule network (DCN) is developed for simultaneous classification and quantification of seagrass based on the multispectral images. The DCN is jointly optimized for classification and regression, and is capable of performing end-to-end seagrass quantification. We separately validated the proposed method on three images taken in Florida coastal area and achieved better results with DCN when compared against a deep convolutional neural network (CNN) model and a linear regression model. In addition, transfer learning strategies are developed to transfer knowledge in a DCN trained at one location for seagrass quantification to different locations with minimum field observations, which saves a significant amount of time and resources in the mapping of seagrass LAI. Our experimental results show that the developed capsule network achieved superb performances in few-shot transfer learning as compared to direct linear regression and traditional CNN models.
Unbiasedness of LRT on the homogeneity of means in MANOVA under general order restrictions

Abstract In this paper a likelihood ratio test is developed through matrix projections for the hypothesis on the homogeneity of mean vectors in MANOVA. It is assumed that the mean vectors are under a general multivariate order restriction. The multivariate order relation in the restriction is a generalization of orders in real numbers. Based on the study of the structure of the acceptance region with respect to a mirror image transformation, and the properties of transformed matrix distributions, the unbiasedness of the test is established.
Response to Rachel Blass.

In her Introduction to a group of commentaries on Melanie Klein's recently published Lectures on Technique (Steiner 2017), Rachel Blass describes me as “a leading figure in American Relational psyc...
NFATc1-E2F1-LMCD1-Mediated IL-33 Expression by Thrombin Is Required for Injury-Induced Neointima Formation

Objective- IL (interleukin)-33 has been shown to play a role in endothelial dysfunction, but its role in atherosclerosis is controversial. Therefore, the purpose of this study is to examine its role in vascular wall remodeling following injury. Approach and Results- Thrombin induced IL-33 expression in a time-dependent manner in human aortic smooth muscle cells and inhibition of its activity by its neutralizing antibody suppressed thrombin induced human aortic smooth muscle cell migration but not DNA synthesis. In exploring the mechanisms, we found that Par1 (protease-activated receptor 1), Gαq/11 (Gα protein q/11), PLCβ3 (phospholipase Cβ3), NFATc1 (nuclear factor of activated T cells), E2F1 (E2F transcription factor 1), and LMCD1 (LIM and cysteine-rich domains protein 1) are involved in thrombin-induced IL-33 expression and migration. Furthermore, we identified an NFAT-binding site at -100 nt that mediates thrombin-induced IL-33 promoter activity. Interestingly, we observed that NFATc1, E2F1, and LMCD1 bind to NFAT site in response to thrombin and found that LMCD1, while alone has no significant effect, enhanced either NFATc1 or E2F1-dependent IL-33 promoter activity. In addition, we found that guidewire injury induces IL-33 expression in SMC and its neutralizing antibodies substantially reduce SMC migration and neointimal growth in vivo. Increased expression of IL-33 was also observed in human atherosclerotic lesions as compared to arteries without any lesions. Conclusions- The above findings reveal for the first time that thrombin-induced human aortic smooth muscle cell migration and injury-induced neointimal growth require IL-33 expression. In addition, thrombin-induced IL-33 expression requires LMCD1 enhanced combinatorial activation of NFATc1 and E2F1.
Determination of dose rate effects on Zircaloy oxidation using proton irradiation and oxygen transport modeling

Abstract While much of our knowledge about zirconium corrosion at high temperatures comes from out-of-pile experiments performed over the last several decades, understanding the behavior of Zr clad in light water reactor (LWR) conditions requires studying corrosion acceleration under irradiation. In-pile tests are slow and costly to perform, and only allow limited flexibility when it comes to exploring key parameters such as dose, dose rate, temperature, and alloy composition. In contrast, proton irradiations provide a good match for LWR dose rates and for the spatial uniformity of neutron irradiation, and thus constitute a very robust experimental platform from which to explore these parameters. In this work, we present an extension of a recently proposed Zr oxidation kinetic model that accounts for acceleration of oxide layer growth due to irradiation, accompanied by a set of controlled experiments carried out in a corrosion loop coupled to an accelerator beam line for parameterization and validation. The model includes radiation enhanced diffusion (RED) of oxygen in the oxide as the main effect of irradiation, and uses the experimental results of oxide layer growth as a function of dose rate to parameterize the RED coefficients. We show that these coefficients are strongly dose rate-dependent, which is quantitatively consistent with a negligible effect of RED on corrosion acceleration in the pre-transition regimes of samples irradiated under LWR conditions. We also find a smooth transition from columnar to equiaxed oxide grain growth as the proton irradiation dose rate increases.
NMR Methods to Characterize Protein-Ligand Interactions:

Structural information pertaining to the interactions between biological macromolecules and ligands is of potential significance for understanding of molecular mechanisms in key biological processe...
Neglected Parasitic Infections and the Syndemic Anemia Vaccines for Africa

Today, malaria, schistosomiasis, and human hookworm infection comprise three of the most common parasitic diseases on the African continent. These neglected parasitic infections also represent important threats to maternal–child health in sub-Saharan Africa, particularly because they cause profound anemia. Malaria, schistosomiasis, and hookworm infection each cause severe anemia, but they are also co-endemic or syndemic and produce additive effects when occurring simultaneously in a single individual, especially a child or pregnant woman. In young children, the combined anemia from these parasitic infections can lead to permanent neurologic deficits, while in pregnant women they are linked to high maternal morbidity and mortality and decreased infant survival. While mass treatments for malaria, schistosomiasis, and human hookworm infection have led to some reductions in maternal–child morbidities in Africa, it is unlikely this approach alone will remain sustainable due to high rates of post-treatment reinfections and other factors, including variable efficacies of the currently available drugs, as well as the prospect of emerging resistance. As complementary or synergistic approaches, there are ongoing efforts to develop vaccines for malaria, human hookworm infection, and schistosomiasis. These biotechnologies would represent innovative approaches to reducing or halting maternal–child health anemia in Africa. Mosquirix is the first malaria vaccine licensed for Africa, while vaccines for schistosomiasis and human hookworm infection are each entering their proof of concept for efficacy in phase 2 clinical trials. New public–private strategic alliances, including the one formed between Merck and Baylor College of Medicine and its international vaccine product development partnership (PDP), the Texas Children’s Hospital Center for Vaccine Development (Texas Children’s CVD), to advance the schistosomiasis vaccine, will be essential to help accelerate vaccine research and development for neglected and emerging infections. These types of partnerships will also require innovative financial instruments to address traditional market failures, allowing licensing and the introduction of anti-parasitic disease vaccines for Africa.
Understanding the Glenoid Avulsion of the Glenohumeral Ligaments as a Cause of Shoulder Instability: Surgical and Postsurgical Management

Abstract In adolescents and young adults, instability is a common shoulder pathology with a myriad of coexisting soft tissue and bony lesions. When evaluating a patient for the cause of instability, care must be given to assess for the infrequent lesions, including glenoid avulsion of the glenohumeral ligaments. This case example illustrates key points in the diagnosis, surgical, and postsurgical management of this less common cause of anterior shoulder instability.
The stipend student commitment to child welfare

ABSTRACTStudent stipend programs are a significant strategy to build the child welfare workforce and encompass a set of specific obligations. This includes the student’s pledge to enter the child w...
Improved work environments and staffing lead to less missed nursing care: A panel study

Aim To document how changes in the hospital work environment and nurse staffing over time are associated with changes in missed nursing care. Background Missed nursing care is considered an indicator of poorer care quality and has been associated with worse patient care experiences and health outcomes. Several systematic reviews of cross-sectional studies report that nurses in hospitals with supportive work environments and higher staffing miss less care. Causal evidence demonstrating these relationships is needed. Methods This panel study utilized secondary data from 23,650 nurses surveyed in 2006 and 14,935 surveyed in 2016 in 458 hospitals from a four-state survey of random samples of licensed nurses. Results Over the 10-year period, most hospitals exhibited improved work environments, better nurse staffing and more missed care. In hospitals with improved work environments or nurse staffing, the prevalence and frequency of missed care decreased significantly. The effect on missed care of changes in the work environment was greater than that of nurse staffing. Conclusions Changes in the hospital work environment and staffing influence missed care. Implications for nursing management Modifications in the work environment and staffing are strategies to mitigate care compromise. Nurse managers should investigate work settings in order to identify weaknesses.
Cognitive factors associated with binge and purge eating behaviors: The interaction of body dissatisfaction and body image importance

This investigation examined the association of body dissatisfaction, body image importance, and the interaction of these variables with the disordered eating behaviors of bingeing and purging. Undergraduate women (n = 311) completed the Shape and Weight Based Self-Esteem Inventory (SAWBS; J. Geller, C. Johnston, & K. Madsen, 1997) to assess body image importance, the Body Esteem Scale (BES; S. L. Franzoi & S. A. Shields, 1984) to assess body dissatisfaction, and a self-report measure of binge and purge frequency. Hierarchical multiple regressions predicting binge and purge behaviors were conducted with body mass index and neuroticism controlled first, SAWBS and BES entered next, and the interaction of SAWBS and BES entered last. A main effects model significantly predicted binge frequency (p < .05), but was not improved by the addition of the interaction term. In contrast, the interaction term made a significant contribution to the prediction of purge frequency (p < .05). These findings indicate that body image importance and body dissatisfaction are both important factors to consider in understanding bulimic behaviors, particularly purge behavior; however, the associations of these variables with binge and purge behaviors may differ.
A fractional-order compartmental model for the spread of the COVID-19 pandemic

Abstract We propose a time-fractional compartmental model (SEI A I S HRD) comprising of the susceptible, exposed, infected (asymptomatic and symptomatic), hospitalized, recovered and dead population for the COVID-19 pandemic. We study the properties and dynamics of the proposed model. The conditions under which the disease-free and endemic equilibrium points are asymptotically stable are discussed. Furthermore, we study the sensitivity of the parameters and use the data from Tennessee state (as a case study) to discuss identifiability of the parameters of the model. The non-negative parameters in the model are obtained by solving inverse problems with empirical data from California, Florida, Georgia, Maryland, Tennessee, Texas, Washington and Wisconsin. The basic reproduction number is seen to be slightly above the critical value of one suggesting that stricter measures such as the use of face-masks, social distancing, contact tracing, and even longer stay-at-home orders need to be enforced in order to mitigate the spread of the virus. As stay-at-home orders are rescinded in some of these states, we see that the number of cases began to increase almost immediately and may continue to rise until the end of the year 2020 unless stricter measures are taken.
A four-pixel single-photon pulse-position array fabricated from WSi superconducting nanowire single-photon detectors

We demonstrate a scalable readout scheme for an infrared single-photon pulse-position camera consisting of WSi superconducting nanowire single-photon detectors. For an N × N array, only 2 × N wires are required to obtain the position of a detection event. As a proof-of-principle, we show results from a 2 × 2 array.