Investigation on iodine deficiency situation of pregnant women in various areas and effect of iodine supplementation intervention

Objective To research iodine nutrition level of four groups of pregnant women in 3 various areas(with iodine deficiency of mild,moderate and severe degrees) of Xinjiang Production and Construction Corps,and change of urine iodine before and after intervention of iodine supplementation,to analyze intervention effect.Methods The area of 3rd type with iodine deficiency and various coverage rates of iodine salt and urine iodine level were selected to investigate the urine iodine level of the pregnant women before and after taking iodinated oil soft capsules.Results Median of urine iodine of the four groups of the pregnant women before intervention was 119.90,147.20,214.00 and 167.10 μg/L,respectively,with proportion of urine iodine number 100 μg/L of 30.0%,,4.3%,42.9% and 20%,respectively.The median was 172.25,148.70,164.50 and 229.80 μg/L,with the proportion of 25.0%,22.2%,19.5% and 0 after intervention 1 month;and 150.00,103.60,176.60 and 219.60 μg/L,with the proportion of 25.0%,47.8%,13.8% and 13.8% after intervention 3 months;119.90,147.20,214.00 and 167.10 μg/L,with the proportion of 25.0%,15.4%,13.8% and 0 after intervention 6 months;173.95,185.20,208.50 and 262.21 μg/L,with the proportion of 21.9%,10.3%,26.1% and 0 after intervention 9 months.Conclusions Intervention with iodine supplementation can make median of urine iodine of pregnant women drift to high value,and significantly improve the Abstract:Objective To research iodine nutrition level of four groups of pregnant women in 3 various areas(with iodine deficiency of mild,moderate and severe degrees) of Xinjiang Production and Construction Corps,and change of urine iodine before and after intervention of iodine supplementation,to analyze intervention effect.Methods The area of 3rd type with iodine deficiency and various coverage rates of iodine salt and urine iodine level were selected to investigate the urine iodine level of the pregnant women before and after taking iodinated oil soft capsules.Results Median of urine iodine of the four groups of the pregnant women before intervention was 119.90,147.20,214.00 and 167.10 μg/L,respectively,with proportion of urine iodine number 100 μg/L of 30.0%,,4.3%,42.9% and 20%,respectively.The median was 172.25,148.70,164.50 and 229.80 μg/L,with the proportion of 25.0%,22.2%,19.5% and 0 after intervention 1 month;and 150.00,103.60,176.60 and 219.60 μg/L,with the proportion of 25.0%,47.8%,13.8% and 13.8% after intervention 3 months;119.90,147.20,214.00 and 167.10 μg/L,with the proportion of 25.0%,15.4%,13.8% and 0 after intervention 6 months;173.95,185.20,208.50 and 262.21 μg/L,with the proportion of 21.9%,10.3%,26.1% and 0 after intervention 9 months.Conclusions Intervention with iodine supplementation can make median of urine iodine of pregnant women drift to high value,and significantly improve the iodine nutrition status in iodine deficiency area.In moderate area of iodine deficiency,pregnant women taking low dose of 200 mg can meet their own needs,while in the severe areas,pregnant women taking large dose of 400 mg can meet their own demand for iodine.Particularly,the intervention obviously affects increase of urine iodine after intervention 1 month and 3 months.