cssi/SciSciGPT-SciSciNet huggingface dataset:
Cardiac nuclear medicine in monitoring patients with coronary heart disease

Patient monitoring is a major indication for cardiac nuclear medicine procedures. Stress myocardial perfusion scintigraphy was initially used for diagnosis, but monitoring patients with coronary artery disease has become more common. Stress myocardial perfusion scintigraphy has been shown to provide a considerable amount of incremental prognostic information, which may be useful in selecting patients for therapy. In patients being considered for revascularization, fluorodeoxyglucose can be used to identify regions of dysfunctional but viable myocardium, even within regions that show fixed defects on stress perfusion imaging. It can be used to select a group of patients who will improve function with revascularization and who may have an improved outcome. Thus, cardiac nuclear medicine plays a pivotal role in monitoring patients with coronary artery disease.
SITE-DIRECTED MUTAGENESIS OF GLYCINE 99 TO ALANINE IN L-LACTATE MONOOXYGENASE FROM MYCOBACTERIUM SMEGMATIS

Abstract L-Lactate monooxygenase (LMO) from Mycobacterium smegmatis was mutated at glycine 99 to alanine, and the properties of the resulting mutant (referred to as G99A) were studied. Mutant G99A of LMO was designed to test the postulate that the smaller glycine residue in the vicinity of the α-carbon methyl group of lactate in wild-type LMO has less steric hindrance, leading to the retention and oxidative decarboxylation of pyruvate in the active site, a unique property of LMO in contrast to other members of the FMN-dependent oxidase/dehydrogenase family. G99A has been shown to be readily reduced by L-lactate at a rate similar to that of the wild-type enzyme. The binding of pyruvate to reduced G99A is 4-fold weaker than that to the wild-type enzyme. A dramatic change of this mutation is that G99A has a much lower oxygen reactivity than the wild-type enzyme. Pyruvate-bound reduced G99A reacts with O2 at a rate ∼105-fold slower than the wild-type enzyme, and free reduced G99A reacts with O2 at a rate ∼100-fold slower than the wild-type enzyme. Due to the very low oxygen reactivity of the pyruvate-bound reduced enzyme, G99A has been shown to catalyze the oxidation of L-lactate to pyruvate and hydrogen peroxide instead of acetate, carbon dioxide, and water, the normal decarboxylation products of pyruvate and hydrogen peroxide. Thus, the mutation alters the enzyme from its L-lactate monooxygenase activity to L-lactate oxidase activity. However, compared with L-lactate oxidase, G99A has a much lower reactivity toward oxygen. Our results also reveal that the small steric change around N-5 of the flavin causes a profound change in the electronic distribution in the catalytic cavity of the enzyme and imply that electrostatic interactions in the active site provide an important factor for control of O2 reactivity.
Lemierre syndrome complicating otitis externa: case report and literature review

Abstract Background: Septic thrombophlebitis of the internal jugular vein, known as Lemierre syndrome, is a rare disorder usually caused by Fusobacterium necrophorum , a Gram-negative anaerobic organism that normally inhabits the oropharynx. Lemierre syndrome usually follows primary oropharyngeal infections and affects previously healthy adolescents and young adults in a characteristic manner, often with fatal results if left untreated. There have been a significantly increasing number of reported cases of Lemierre syndrome, possibly reflecting the trend to withhold antibiotics for initially uncomplicated oropharyngeal infections. Objectives: We hope to alert the reader to a potentially fatal disease process that has recently been increasingly identified, by reporting a unique manifestation of Lemierre syndrome, and by reviewing the current literature. Case Report: A 19-year-old woman presented to our Emergency Department with a chief complaint of fever, ear pain, and generalized weakness. She was noted to be in septic shock, with left neck erythema and swelling. A computed tomography scan showed thrombosis of the left internal jugular vein (IJV), which was later excised. She recovered after a course of intravenous and oral antibiotics. Conclusion: Septic thrombophlebitis of the IJV is associated with multiple sources and organisms. This case is unique in both the organism ( Peptococcus anaerobius ) and the source (otitis externa). This disease process must be identified early and aggressively treated to avoid significant morbidity and mortality.
Anode/cathode make and break phenomena in a model of defibrillation

The goal of this simulation study is to examine, in a sheet of myocardium, the contribution of anode and cathode break phenomena in terminating a spiral wave reentry by the defibrillation shock. The tissue is represented as a homogeneous bidomain with unequal anisotropy ratios. Two case studies are presented in this article: tissue that can electroporate at high levels of transmembrane potential, and model tissue that does not support electroporation. In both cases, the spiral wave is initiated via cross-field stimulation of the bidomain sheet. The extracellular defibrillation shock is delivered via two small electrodes located at opposite tissue boundaries. Modifications in the active membrane kinetics enable the delivery of high-strength defibrillation shocks. Numerical solutions are obtained using an efficient semi-implicit predictor-corrector scheme that allows one to execute the simulations within reasonable time. The simulation results demonstrate that anode and/or cathode break excitations contribute significantly to the activity during and after the shock. For a successful defibrillation shock, the virtual electrodes and the break excitations restrict the spiral wave and render the tissue refractory so it cannot further maintain the reentry. The results also indicate that electroporation alters the anode/cathode break phenomena, the major impact being on the timing of the cathode-break excitations. Thus, electroporation results in different patterns of transmembrane potential distribution after the shock. This difference in patterns may or may not result in change of the outcome of the shock.
Deletions in Chromosome 22q11 Region in Cervical Aortic Arch

Two patients with cervical aortic arch are described, both with deletions in chromosome 22q11 region, and thymic hypofunction. This suggests that cervical aortic arch is part of the spectrum of the CATCH 22 group of defects.
Optoelectronics opportunities in local area networks

The proliferation of multimedia and Internet applications in local area networks (LANs) has greatly increased bandwidth requirements and led to faster transmission protocols. These developments point toward opportunities for cost-effective optoelectronic components for use in these new high-speed networks. If some real and perceived disadvantages to utilizing optoelectronics in LANs can be overcome, the demand for optoelectronic solutions will increase dramatically.
Detection of Symptoms of Prevalent Mental Health Disorders of Childhood with the Parent Form of the Behavioral and Emotional Screening System.

This study examined the criterion-related validity of score inferences from the Behavioral and Emotional Screening System Parent Form (BESS Parent) for the detection of symptoms of prevalent mental health disorders of childhood. The BESS Parent was administered to 99 parents of first- through fifth-grade students, along with the Child Behavior Checklist (CBCL). Correlations were computed between the BESS Parent total and researcher-calculated subscale scores, and Diagnostic and Statistical Manual (DSM)–oriented scales of the CBCL. Moderate correlations were obtained between the BESS Parent total score and CBCL DSM-oriented conduct problems, oppositional defiant, attention deficit/hyperactivity disorder, and affective problems scales, and with the CBCL externalizing, internalizing, and total problems composite scores. Results support interpreting the BESS Parent as a measure of risk and as an indicator of the potential presence of one of the common mental health disorders of childhood.
INCORPORATING RADIATION INPUTS INTO THE SNOWMELT RUNOFF MODEL

Process-based, distributed-area snowmelt runoff models operating at small scales are essential to understand subtle effects of climate change, but require data not commonly available. Temperature index models operating over large areas provide realistic simulations of basin runoff with operationally available data, but lack rigorous physically based algorithms. A compromise between the two types of models is required to provide realistic evaluations of basin response to environmental changes in cold regions. One adaptation that is uniformly required for snowmelt models is the use of remotely sensed data, either as input or in model validation. At a minimum, snowmelt forecasting models need to incorporate snowcover extent information, which is currently obtained operationally. As more remote sensing capabilities come on line, models should accept upgraded information on snow water equivalent; additional remotely sensed information on landcover, frozen soil, soil moisture, cloudiness and albedo would also be useful. Adaptations to the semi-distributed snowmelt runoff model (SRM) are underway to make it more physically based for use in large area studies. A net radiation index has been added to the model, which formerly used only a temperature (degree-day) index to melt snow from a basin's elevation zones. The addition of radiation to the SRM allows the basin to be subdivided into hydrological response units by general aspect (orientation) as well as elevation. Testing of the new radiation-based SRM with measured radiation from a small research basin is the first step towards large scale simulations. Results from the W-3 research basin in Vermont, USA are promising. In the radiation version, the factor that multiplies the degree-day index is estimated independently of model output and is held constant throughout the season, in contrast with the degree-day version, where the corresponding factor is allowed to increase throughout the season. Without calibrating or optimizing on this important parameter, the goodness-of-fit measure R 2 is improved in two out of six test years when the radiation version of the SRM is used in place of the degree-day version in melt season simulations. When the accumulation of error is eliminated with periodic updating of streamflow, more significant improvement is noted with radiation included.
Realism, instrumentalism, and the Intentional Stance*

One of Dennett's principal arguments for an instrumentalistic construal of intentional attributions (e.g., attributions of belief, etc.) is that such attributions are environment relative. I argue that one can and should adopt a realist perspective toward such attributions, but accommodate their environmental relativity by treating intentional properties as relational properties. By doing so one acquires a useful perspective on experimental cognitive psychology; in particular, one can overcome the temptation to treat ecological accounts and information processing accounts as incompatible alternatives and come to see them as mutually supportive. Treating intentional properties as relational may be counter-intuitive, but I provide examples of how other sciences have had to treat what seem to be intrinsic properties as relational.
Cytoplasmic incompatibility and mating preference in Colombian Drosophila pseudoobscura

MACRAE and ANDERSON observed a large frequency change of mitochondrial DNA (mtDNA) haplotypes in a population initiated with two allopatric strains of Drosophila pseudoobscura, BogER from Colombia and AH162 from California. They concluded that mtDNA haplotypes in D. pseudoobscura are not always selectively neutral. NIGRO and PROUT suggested, however, that a maternally transmitted incompatibility system, similar to the one they observed in two strains of D. simulans from Italy, could account for the observed mtDNA frequency changes. SINGH and HALE postulated that a mating preference between the strains BogER and AH162 in MACRAE and ANDERSON's experiment, in the form of negative assortative mating, could also account for the mtDNA frequency changes. We report two experiments designed to test the hypotheses: that a maternally transmitted cytoplasmic incompatibility system exists between D. pseudoobscura strains BogER and AH162; and, that BogER females mate preferentially with AH162 males. Our results do not support either hypothesis.
Attitudes, perceived norms, and intentions: a needs assessment study of the influenza immunization intentions of elderly citizens in Vermont.

Context Influenza and pneumonia rank among the 5 leading causes of death among persons aged 65 and over. Although immunization has been demonstrated to prevent influenza or reduce its incidence and associated complications among the elderly, it has been largely underutilized. Purpose This study examined the association of attitudes, perceived norms, and intention to obtain influenza immunization among community-dwelling rural elderly. The goal was to design an effective intervention program to increase the rate of flu immunization among the rural elderly. Methods In spring 2000, random-digit dialing selected 1,239 households in 2 rural Vermont counties. Telephone interviews were conducted with 799 persons aged 60 or older, resulting in a response rate of 65%. Findings Factor analyses revealed 2 dimensions underlying attitudes and perceived norms. Subsequent regression analyses confirmed that 1 attitude construct--perceived benefits--and both normative indices were significant predictors of immunization intention, explaining 45% of its variation. Conclusions An intervention program targeting rural elderly should emphasize the benefits and perceived side effects of immunization. The program should publicize that most elderly believe that the advantages of influenza immunization outweigh the disadvantages. These findings will inform an intervention program designed to increase immunization coverage among rural seniors in Vermont.
The Role of Protein Kinase C in Thromboxane A2-Induced Pulmonary Artery Vasoconstriction

In order to determine if protein kinase C (PKC) plays a significant role in the stimulant action of thromboxane A2 (TxA2) on pulmonary vascular smooth muscle, TxA2-induced contractile responses were measured following inhibition of PKC. Rabbits were sacrificed and segments of the main trunk of the pulmonary artery were removed and placed within a temperature-controlled (37°C) organ bath. Contractile responses that were evoked by a TxA2 mimetic (U46,619, 0.5 μM) decreased by 27 and 35% following treatment with the PKC inhibitors, calphostin C (2 μM) and staurosporine (200 nM), respectively. These results account for the effect of the vehicle, DMSO, which was also found to have a concentration-dependent inhibitory effect on the U46,619-induced contractions. The effects of DMSO alone was subsequently subtracted from the previously measured responses to PKC inhibitors that were dissolved in DMSO to obtain effects attributable to the PKC inhibitor alone. It can therefore be concluded that inhibition of PKC results in partial attenuation of U46,619-induced responses supporting the hypothesis that activation of PKC plays a partial role in TxA2-induced contraction of pulmonary arterial smooth muscle.
Blood, growth, and other characteristics of special-fed veal calves in private cooperator herds

The objectives of this study were to determine the mean values for mortality, blood, and growth traits and the correlations among blood and growth traits on privately owned farms producing special-fed veal. Mortality percentages were available on 13 groups of special-fed veal calves (n = 1403) from four farms; growth and some blood traits were available on 9 groups from four farms (n = 975). Mean mortality percentages for periods 0 to 2, 2 to 7, and 7 to 16 wk, and over 16 wk were 1.0, 1.0, 1.0, and 3.1%, respectively. Means for average daily gain for 2 to 7 wk were 1.37 +/- .008 kg and for 7 to 16 wk were 1.52 +/- .001 kg. When calves arrived at the veal farm, total plasma protein averaged 6.2 +/- .05 g/dl. Examination of total plasma protein upon arrival of calves indicated that 81% of the calves had received colostrum. The base level indicating colostral deficiency was 6.0 g/dl at arrival. Mean hemoglobin concentrations at arrival and at 2, 7, and 16 wk were 11.1 +/- .15, 10.6 +/- .18, 9.2 +/- .14, and 7.8 +/- .13 g/dl, respectively. Means for hemoglobin were generally higher than previously reported for special-fed veal calves reared in individual stalls. Hemoglobin and red blood cell counts were correlated positively with 16-wk average daily gain and body weight, and midtrial white blood cell counts were correlated negatively with average daily gain and body weight from 2 to 7 wk; there were no other significant relationships between blood traits and growth performance measures.
Political party use of radio and television in the 1960 campaign

Although only about 1% of all broadcast revenues in 1960 could be attributed to time purchased for the Presidential election campaign, the total (close to $14 million) was enough to put a very‐large dent into political party treasuries. At the same time, broadcasting stations and networks reaped a quadrennial bonanza. The following article describes and discusses the trends in party expenditures for political broadcasting, as well as the regional distribution of the amount of broadcasting time purchased by the two major parties. It is primarily an analysis of the Federal Communications Commission's 1960 Survey of Political Broadcasting.
Kerr rotations and anisotropy in (Pt/Co/Pt)/X multilayers

The link between interface sharpness and perpendicular magnetic anisotropy (K/sub /spl perp//) in Pt/Co multilayers has been exploited to yield enhanced magnetic anisotropy in related multilayer structures. These new multilayers consist of a (Pt/Co/Pt)/Pd stacking sequence where the Pt thickness is of just one atomic monolayer. The extra interfaces per period are introduced in areas where the spin polarization is still expected to be large thus resulting in extra magnetic anisotropy. K/sub /spl perp// as high as 5/spl times/10/sup 7/ erg/cm/sup 3/ was measured in Xe sputtered films with this new period. This idea was extended to (Pt/Co/Pt)X systems with X=Ag, Cu, Ni. A ten fold increase in K/sub /spl perp// is observed in these films compared to their respective Co/X counterparts. The Kerr rotation (/spl theta/K) as a function of photon wavelength is also greatly enhanced by the presence of the Pt monolayers. A strong dependence of /spl theta/K on the spacer element X in these systems is observed.
Combining dependence and data-flow analyses to optimize communication

Reducing communication overhead is crucial for improving the performance of programs on distributed-memory machines. Compilers for data-parallel languages must perform communication optimizations in order to minimize this overhead. In this paper, we show how to combine dependence analysis, traditionally used to optimize regular communication, and a data-flow analysis method originally developed to improve placement of irregular communication. Our approach allows us to perform more extensive optimizations message vectorization, elimination of redundant messages, and overlapping communication with computation. We also present preliminary experimental results that demonstrate the benefits of the proposed method. >
Eric Harris Davidson: A systems biologist who studied how genomes function.

The phrase “force of nature” has popped up repeatedly in social media responses to the announcement of Eric Davidson’s death on September 1, 2015. This sobriquet reflects his huge influence on the fields of developmental biology and evolution. His career began about the time Watson and Crick published the structure of DNA, and his contributions continued into the genomic era in which we are now immersed. But his stature wasn’t due to this timing. As Pasteur once said: “Dans les champs de l’observation le hasard ne favorise que les esprits prepares.” (“In the fields of observation chance favors only the prepared mind”). Perhaps Eric’s strong focus on the function of the genome and his great intellect also contributed to this influence. His unwavering focus on how the genome does its job must also play a role. Furthermore, he clearly took genuine delight in confronting complex biological problems, and he erected broad views of the process of nature. This point is documented in his dedication to the third edition of Gene Activity in Early Development, where he credits his father with teaching him about organizing complex perceptions. Eric Davidson was born on April 13, 1937 in New York City, New York. He is the son of Morris and Anne Davidson. His father was a renowned abstract painter of the mid-20th century who maintained a school of painting near Provincetown on Cape Cod, Massachussetts. Eric attended the University of Pennsylvania as an undergraduate, and earned a Ph.D. from Rockefeller University (then Institute). He continued at Rockefeller as a post-doc, and then as assistant professor until 1971. He then moved to the California Institute of Technology, where he remained for the remainder of his career.
Customary law as a social contract: International commercial law

Merchants broke the bonds of localized political constraints during the tenth and eleventh centuries to establish the constitutional foundations of international commercial law as we see it today. The medieval “Law Merchant” was an international legal system that governed without the centralized coercive power of the state. In order to see how this was possible, the incentives which led to the merchants community's social contract, as well as the rules and institutional arrangements that the resulting contract produced are examined and explained. A process of legal change evolved, participatory institutions were established to adjudicate disputes and effective incentives were implemented to induce compliance with the resulting judgements. The unwritten social contract established by the medieval business community remains in force to this day. International commercial law is still largely independent of nationalized legal systems, retaining many of the basic (though) modernized institutional characteristics of the medieval Law Merchant. James Buchanan suggested that “Free relations among free men—this precept of ordered anarchy can emerge as principle,” under an appropriately structured social contract. The international Law Merchant provides a historical and modern demonstration that Buchanan is indeed correct.
Photorefractive Volume Holographic Memories for Associative Storage and Processing in a Multimedia Environment

Photorefractive volume holographic memories can be used to realize fast data searches because they allow associative data recall. We have developed a prototype of a volume holographic database system and examined its potential use for a number of applications in a multimedia environment, including database management, video indexing, and interactive video. The experimental results presented in this paper demonstrate that associative recall is possible with any combination of digital (binary) and analog (image) data.
Nine cases undergoing surgical removal of subglottic hemangioma

We experienced nine female cases of infantile subglottic hemangioma during the period from 1984 to 1992. Characteristic clinical symptoms, surgical repair and postoperative courses are presented. Supraclavicular, xyphoid, as well as stridor, were the presenting symptoms in all cases. In addition, six cases had a barking cough. These symptoms developed one to two months postnatally, none having been present at birth. Five cases were treated with steroids, resulting in a marked improvement in dyspnea. Four patients also had hemangiomas in another anatomical location. Eight of the nine cases underwent surgical repair. Tracheotomy was done and the hemangioma was removed through a laryngofissure under a surgical microscope. We separated the overlying laryngeal mucosa, removed the tumor and then closed the epithelium with fibrin paste. Seven of these eight cases were successfully decannulated 20 days to 6 months later. Outcomes were good. The surgical technique employed produces no scarring, thereby avoiding laryngeal stenosis. One of the nine cases underwent tracheotomy and the hemangioma was vaporized with an Nd-YAG laser under a laryngeal microscope.
Acting with One Voice: Producing Unanimism in Algerian Reformist Theater

Scholars of democracy from Tocqueville to Habermas have long considered the proliferation of so-called voluntary associations as a sign of a flourishing civil society and as central to the rise of democratic modernity. I contend that the Algerian theatrical and musical associations of the reformist period anticipate another kind of civic history: a history of displays of unanimism in public life. I am interested in how and why Algerians learned to produce public displays of agreement for particular audiences (including themselves) at particular historical moments. I emphasize three factors that contributed to the production of unanimity: the achievement of tawḥīd or unity in the Islamic reform movement, vernacular practices of consensus-based argumentation, and French colonial legal and surveillance mechanisms. The essay engages theories of civil society, colonialism, and performance. It draws primarily on material from the French colonial archives for the city of Constantine, Algeria.
Backdoor Diplomacy in the Pacific: The Proposal for a Konoye-Roosevelt Meeting, 1941

THE prospect of maintaining peace in the Pacific in 1941 had never seemed more tenuous than it did in mid-August of that crisis-ridden year. The movement of Japanese military forces into southern Indochina in July had prompted the American government to freeze Japan's assets, thus bringing economic relations to a standstill. These events in tandem had added a new dimension of urgency to the existing political and strategic confrontation between the two countries. The diplomatic conversations that had been in progress in Washington for nearly six months were concurrently mired in complications, obscurantism, and confusion. Among the reasons for this, unappreciated at the time, was the virtually invisible but very substantial damage caused by an unusual partnership between Japan's envoy to the United States, Admiral Kichisaburo Nomura, and the "John Doe Associates"-a state department term that will be used here to allude to three individuals who were acting in concert behind the scenes: James M. Drought, the politically minded vicar general of the Catholic Foreign Mission Society of America with headquarters at Maryknoll, New York; Hideo Iwakuro, an adroit Ministry of War colonel on special assignment as an adviser to Nomura; and Tadao Paul Wikawa, a Japanese Christian from the world of banking and finance who claimed to be serving as a confidential agent for the premier of Japan and who functioned as a vital link between Iwakuro and Drought, neither of whom spoke the other's language.1
Dual-Band Perfect Absorber for Multispectral Plasmon-Enhanced Infrared Spectroscopy

Metamaterial-based perfect absorbers utilize intrinsic loss, with the aid of appropriate structural design, to achieve near unity absorption at a certain wavelength. For most of the reported absorbers, the absorption occurs only at a single wavelength where plasmon resonances are excited in the nanostructures. Here we introduce a dual-band perfect absorber based on a gold nanocross structure. Two bands of maximum absorption of 94% are experimentally accomplished by breaking the symmetry of the cross structure. Furthermore, we demonstrate the two bands can be readily tuned throughout the mid-infrared with their associated resonances giving rise to large near-field enhancements. These features are ideal for multiband surface-enhanced infrared spectroscopy applications. We experimentally demonstrate this application by simultaneously detecting two molecular vibrational modes of a 4 nm thick polymer film utilizing our proposed absorber. Furthermore, in response to variations in the interaction strength betwee...
Permissions, Ownership, and Auditing

Windows offers lots of very powerful features to prevent unauthorized access to your corporate data. The majority of these are available only when you use the New Technology File System (NTFS) that we reviewed in Chapter 2. In this chapter, we will delve further into the specifics of NTFS and focus on the features that allow you to secure your files by applying various permissions to accept or restrict access. We will provide you guidance on how to re-take ownership to gain control of orphaned files and, finally, review options for low-level fine-grained auditing of files and folders that are useful when investigating whether users are accessing (or attempting to access!) restricted files.
Pelvic Lipomatosis: 9-Year Followup in a Woman

Pelvic lipomatosis is uncommon in female subjects. The symptoms and signs are vague in all patients but radiologic studies, especially pelvic computerized tomography, should provide data for the diagnosis and obviate operative intervention. All patients should have careful followup to rule out obstructive uropathy.
Media Genealogy| As If, or, Using Media Archaeology to Reimagine Past, Present, and Future: An Interview with Lori Emerson

Jay Kirby, PhD student in the Communication, Rhetoric, and Digital Media program at North Carolina State University, conducted this interview with Associate Professor Lori Emerson to focus on her research about how interfaces and the material aspects of media devices affect our uses and relationships with those devices. Emerson, who runs the University of Colorado’s Media Archaeology Lab, explains how we can look at older technology that never became an economic success to imagine what could have been and reimagine what is and what could be. In the Media Archaeology Lab, Emerson collects still-functioning media artifacts to demonstrate these different possibilities. In this interview, Emerson draws on examples from digital computer interfaces, word processors, and other older media to show how their material aspects are bound up in cultural, commercial, and political apparatuses. By bringing these issues to light, Emerson shows how a critical eye toward our media can have far reaching implications.
Reading ‘things’ in Italian-America

Drawing from recent work in ‘thing theory’, this essay examines the significance of ‘things’ in Italian-American immigrant texts, focusing on narratives and photographs from 1880 to 1924. It explores the special importance of ‘things’ such as clothing that enable bodily transformation, constituting a vehicle through which new immigrants’ marginal racial status – their ‘probationary whiteness’ – could be negotiated. The essay reads narrative depictions of ‘things’ as means of racial and national ‘assimilation’ against counterdepictions of objects brought from ‘home’ that register how, in Peter Stallybrass’ words, ‘history, memory and desire [can be] materialized in objects that are touched and worn and loved’.
Addressing the Challenges with Global Mindset

Henson proposes a model for gaining a better understanding of global leadership. The model proposes that global leadership has certain antecedents, the most important of which are cultural intelligence (CQ), certain personality traits, cross-cultural contacts and experiences, and self-awareness. These antecedents impact the development of global leadership, which is made up of foundational requirements (organizational and business savvy, results-orientation, and integrity/ethics); global mindset dispositions (flexibility, acceptance, curiosity, and empathy); and competencies (intercultural communication skills, cultural sensitivity, and learning agility). Successful outcomes for global leaders depend on a fit between these components and the context (including organizational, developmental, and situational) in which global leadership is implemented. Outcomes for global leadership include personal, relationship, performance, and organizational. Henson then cautions against the potential perils of authentic leadership when leading cross-culturally.
The Political Economy of Health Care in Senegal

In 1978 in the city of Alma Ata of the former Soviet Union, the World Health Organization declared its intention to provide "health for all by the year 2000." In the third world, this was to be achieved through the integration of "traditional and modern medicine." In the case of Senegal, the prescription was ahistorical. It did not take into account several centuries of integration in all areas, including health care. The central argument here is that four centuries of activity have made integration an historical fact for the peoples of Senegambia. The results of that integration are manifested in the inadequacies of the current health care system which evolved through the contestations of various political economic polities for control of the Senegambian region.
Computing the Globally Optimal Frictionless Fixture in a Discrete Point Set

This paper presents an algorithm to compute the globally optimal fixture with frictionless contacts in a discrete point set on an object. The capability of a fixture to immobilize the object is evaluated by the minimum of the largest conflict of the object with the contacts over all motion directions, which can be reduced to the radius of the largest origin-centered ball contained in the convex hull of primitive contacts wrenches. All candidate fixtures (combinations of the discrete points of a certain number) are expressed in a tree structure, in which each node contains a discrete point representing a contact location and each path from the roots to a leaf represents a fixture. A preorder walk of the tree is performed to search for the optimal fixture. Necessary conditions are derived to predict whether the subtree of a node contains a better fixture. If any necessary condition is not met, then all the fixtures contained in the subtree can be simply rejected. By this means only a small portion of the tree will be traversed and the globally optimal fixture can be found more quickly. This algorithm has been tested on various three-dimensional objects and has been found to be over ten times faster than the brute-force search.
A comparison of DNA extraction methods for high-throughput DNA analyses.

The inclusion of next-generation sequencing technologies in population genetic and phylogenetic studies has elevated the need to balance time and cost of DNA extraction without compromising DNA quality. We tested eight extraction methods — ranging from low- to high-throughput techniques — and eight phyla: Annelida, Arthropoda, Cnidaria, Chordata, Echinodermata, Mollusca, Ochrophyta, and Porifera. We assessed DNA yield, purity, efficacy, and cost of each method. Extraction efficacy was quantified using the proportion of successful polymerase chain reaction (PCR) amplification of two molecular markers for metazoans (mitochondrial COI and nuclear Histone 3) and one for Ochrophyta (mitochondrial nad6) at four time points — 0.5, 1, 2, and 3 years following extraction. DNA yield and purity were quantified using NanoDrop absorbance ratios. Cost was estimated in terms of time and material expense. Results show differences in DNA yield, purity, and PCR success between extraction methods and that performance also varied by taxon. The traditional time-intensive, low-throughput CTAB phenol-chloroform extraction performed well across taxa, but other methods also performed well and provide the opportunity to reduce time spent at the bench and increase throughput. This article is protected by copyright. All rights reserved.
Vascular Anatomy of the Lower Limbs

This chapter begins with a discussion of the arterial system of the lower limb followed by a discussion of the concept of angiosomes. The chapter concludes with a description of venous drainage.
DESIGN CONSIDERATIONS IN ADVANCED GAS TURBINE COMBUSTION CHAMBERS

Publisher Summary This chapter discusses design considerations in advanced gas-turbine combustion chambers. The basic geometry of a combustion chamber is largely dictated by the need to achieve efficient combustion with the minimum of pressure loss and at overall mixture strengths that lie well outside the inflammability limits of kerosine air mixtures. However, within the limits imposed by these considerations, appreciable variations can be made in the amount of air participating in primary combustion, the size of the eddies created in the primary zone, and the degree of mixing achieved between the fuel and air. Small changes in any one of these variables can have a marked effect on combustor characteristics, and their combined effect is to allow considerable scope and flexibility in chamber design. As designers gain more confidence in exploiting these variables, the all-purpose type of combustion unit that is prevalent today will gradually disappear to be replaced by combustors that are tailor-made to meet a few specific combustion requirements.
Well-differentiated neuroendocrine tumors in skin: Terminology and diagnostic utility of cytokeratin 5/6 and p63.

Background Well-differentiated neuroendocrine tumors (WDNETs) in skin include metastases from visceral primary sites and very uncommonly, primary cutaneous carcinoid tumors. Cutaneous WDNET may present a diagnostic challenge and in particular can be mistaken for a benign skin adnexal tumor. In contrast to cutaneous adnexal tumors, metastatic adenocarcinomas to the skin are cytokeratin 5/6 (CK5/6) and p63 negative in the majority of cases. It is unclear if failure to stain with CK5/6 and p63 would be helpful in differentiating WDNETs from cutaneous adnexal neoplasms. Methods We reviewed 10 cases of cutaneous WDNETs (8 cases of metastatic disease and 2 presumed primary carcinoid tumors of the skin) and performed immunohistochemical stains for CK5/6 and p63 on all cases. Results All 10 cases were negative with both CK5/6 and p63. Conclusion Negative staining for CK5/6 and p63 can be helpful to distinguish WDNETs from cutaneous adnexal neoplasms. It is important to consider WDNETs in the differential diagnosis of cutaneous adnexal neoplasms as low-grade tumors may be the first sign of aggressive metastatic disease.
Dance on Camera at 45

This is a review of the Dance on Camera Festival that took place in January 2017 in New York City at Lincoln Center.
Diversity on Corporate Boards: How Much Difference Does Difference Make?

In recent years, increasing attention has focused on the influence of gender and racial diversity on boards of directors. Sixteen countries now require quotas to increase women's representation on boards, and many more have voluntary quotas in corporate governance codes. In the United States, support for diversity has grown in principle, but progress has lagged in practice, and controversy has centered on whether and why diversity matters. The stakes in this debate are substantial. Corporate boards affect the lives of millions of employees and consumers, and the policies and practices of the global marketplace. As recent scandals demonstrate, failures in board governance can carry an enormous cost; Enron is a notorious example. Who gains access to these boards is therefore an issue of broad social importance.This article argues that increasing diversity should be a social priority, but not for the reasons often assumed. Part II begins the discussion by reviewing the underrepresentation of women and minorities on corporate boards. Part III provides a comprehensive review of the research on board diversity, financial performance, and good governance and concludes that the "business case for diversity" is less compelling than other reasons rooted in social justice, equal opportunity, and corporate reputation. Part IV turns to the barriers to achieving greater diversity, and Part V explores strategies that could address them.
Isolation of Rab5-positive endosomes reveals a new mitochondrial degradation pathway utilized by BNIP3 and Parkin

Degradation of mitochondria is an important cellular quality control mechanism mediated by two distinct pathways: one involving Parkin-mediated ubiquitination and the other dependent on mitophagy receptors. It is known that mitochondria are degraded by the autophagy pathway; however, we recently reported that the small GTPase Rab5 and early endosomes also participate in Parkin-mediated mitochondrial clearance. Here, we have developed a protocol to isolate Rab5-positive vesicles from cells for proteomics analysis and provide additional data confirming that mitophagy regulators and mitochondrial proteins are present in these vesicles. We also demonstrate that the mitophagy receptor BNIP3 utilizes the Rab5-endosomal pathway to clear mitochondria in cells. These findings indicate that a redundancy exists in the downstream degradation pathways to ensure efficient mitochondrial clearance.
Driven By Big Data: Are Our Students Prepared? Requiring Technology Coursework in University Sales Programs: An Abstract

The challenges faced by organizations trying to adopt and implement new technologies within their sales forces continue to grow, despite the widespread attention given to them by academics and practitioners. Increasingly sophisticated advances in hardware and software are creating unprecedented expectations and requirements for not only current salespeople but future selling professionals, too. This paper suggests current university-based sales programs may not be supplying their students with the applicable knowledge and skill sets related to sales technology they will need not only for their success but their employers’ success as well.
NEEDED: A NEW SYSTEM OF INTELLECTUAL PROPERTY RIGHTS

The world's current system of intellectual property rights has in recent years become unworkable and ineffective. Designed more than 100 years ago to meet the needs of an industrial era, it is inadequate to handle the ownership and distribution of intellectual property generated by the brainpower industries that have come to dominate the world's economy. The prevailing wisdom is that minor tweaking can remedy the problem. But MIT economist Lester Thurow challenges such thinking and calls instead for a new system--one redesigned from the ground up. In making his case for why the old system doesn't work anymore, Thurow lays out the challenges the new system must meet. It must offer incentives to inventors that are strong enough to offset the decline in publicly funded research. At the same time, it must protect the public interest by keeping some intellectual property--basic scientific knowledge, for example--in the public domain. The new system must be flexible enough to deal with the fact that new technologies have created new potential forms of intellectual property rights (Can pieces of a human being be patented?) and have made old rights unenforceable (When books can be downloaded from an electronic library, what does a copyright mean?). And in an increasingly global economy, a new system must meet the needs of both "catch-up" states and "keep-ahead" states. A system that ignores the lesson of history--that every country that has caught up has done so by copying--will be an unenforceable one.
Thermal ablation versus surgical resection for localized hepatocellular carcinoma: a population study using the SEER database.

Aim To compare overall survival (OS) and liver cancer-specific survival (LCSS) in patients with localized hepatocellular carcinoma treated with surgical resection (SR) or thermal ablation (TA) using the Surveillance, Epidemiology and End Results database. Materials & methods Kaplan-Meier, competing risk and Cox regression analyses were performed after identifying patients. Propensity score matching was then applied. Results There was significantly better OS in the SR group and significantly lower probability of LCSS in the TA group. After matching, there was significantly longer OS in the SR group and a lower probability of LCSS in the TA group. Conclusion SR offered a significant survival benefit over TA for localized hepatocellular carcinoma.
Wave Momentum Flux—A GARP Problem

The energy and momentum removed from the troposphere and lower atmosphere by the breaking of large amplitude mountain lee waves may be a significant factor in the evolution and maintenance of the large-scale atmospheric circulation. A program is outlined for improving knowledge and understanding of this phenomenon and for incorporating its effects into numerical simulation and forecasting models.
Study of the I = 2 Σπ system in π + N interactions

A study of the effective-mass distributions for systems recoiling against mesons (k/sup +/) produced both in pi /sup -/ + p and pi /sup -/ + n interactions is reported. Although all the known energetically accessible resonances are produced the data show no systematic enhancement that can be identified as arising from an I = 2 Y pi resonant state. A more favorable situation exists for SIGMA /sup -/ pi /sup 0/ and SIGMA /sup 0/ pi /sup -/ systems recoi ling against mesons(k/sup +/). The effective-mass distributions for all two-body final states produced in association with mesons(k/sup +/) are plotted. (C.E.S.) perimentally observed nucleon-nucleon scattering. Requirements of unitarity were not imposed, and the dispersion relations depend only on causality and the empirical spectrum of masses, spins, parities, and coupling constants. (C.E.S.)
Experimental Analysis of UWB OFDM Software-Defined Radar Performance for Ad-Hoc Networked Systems

Radar and communication fusion for covert scenarios is a viable topic nowadays due to spectrum crowding and the desire to enhance functionality of RF systems. Software-defined OFDM systems are increasingly considered to fill the role of such multi-functional framework with a potential for covertness of operations. In our work, we introduce a simple and effective method of designing waveforms for radar and communications and describe a setup of simultaneous radar imaging and data transmission. We illustrate the method’s implementation via experimental results that demonstrate a capability of simultaneous sensing and communications between two un-synchronized platforms.
Complex dynamics in a stratified lid-driven square cavity flow

The dynamic response to shear of a fluid-filled square cavity with stable temperature stratification is investigated numerically. The shear is imposed by the constant translation of the top lid, and is quantified by the associated Reynolds number. The stratification, quantified by a Richardson number, is imposed by maintaining the temperature of the top lid at a higher constant temperature than that of the bottom, and the side walls are insulating. The Navier–Stokes equations under the Boussinesq approximation are solved, using a pseudospectral approximation, over a wide range of Reynolds and Richardson numbers. Particular attention is paid to the dynamical mechanisms associated with the onset of instability of steady state solutions, and to the complex and rich dynamics occurring beyond.
Airflow limitation more than doubles the risk for hospitalization/mortality in patients with heart failure.

Background:Comorbid chronic obstructive pulmonary disease is found in approximately one-third of patients with heart failure. Survival in patients with chronic obstructive pulmonary disease general...