cssi/SciSciGPT-SciSciNet huggingface dataset:
Long‐Term Follow Up of Secundum Atrial Septal Defect Closure with the Amplatzer Septal Occluder

Background. During the past 15 years, closure of a secundum atrial septal defect (ASD) has moved from a surgical to a percutaneous transcatheter approach. Few long-term studies of the efficacy and safety of closure of an ASD by an Amplatzer septal occluder (ASO) exist. Methods. To examine the long-term results of secundum ASD closure using the ASO, data on 94 patients who underwent secundum ASD closure with the ASO between 1998 and 2002 were available and reviewed. Data regarding residual shunt, chest pain, palpitations, arrhythmias, headaches, transient ischemic attacks, cerebrovascular accidents, and mortality were collected. Results. Seven (7.4%) subjects had residual shunts immediately following ASO placement. During follow-up, 4 residual shunts closed for a complete closure rate of 97%. Eighteen (19%) patients reported chest pain during the follow-up period. Twenty-three patients (24%) reported palpitations during the follow up period, 7 were documented arrhythmias, including supraventricular tachycardia, atrial fibrillation, and premature ventricular beats. Migraine headaches were new-onset in 4 patients. Migraine cessation occurred in 2 patients after secundum ASD closure. One child died from a cerebral vascular event 18 months following device placement. Only 1 patient developed mild aortic insufficiency. Conclusion. These data indicate that for up to 120 months of patient follow-up, the ASO continues to be a safe device. Residual shunts and arrhythmias have low incidence post-ASO placement. Given the mortality in one high-risk patient, further investigation into anti-platelet therapy after device placement is warranted.
Couch the Bricoleur: Using Ethnographic and Laboratory Traditions to Establish Data Careers

Carl Couch reinvigorated the Iowa School of Symbolic Interaction by combining the theoretical and methodological tenets of ethnography and laboratory science. He thus resembled a bricoleur, or researcher who masters several seemingly diverse practices in order to create a seamless whole. Couch’s new Iowa School also produced a bricolage, or a sum total of research findings, that I call a data career. This article pays tribute to Couch the bricoleur and his bricolage by elaborating on his data career and discussing how he created ethnographies in the laboratory. I further link the notions of bricoleur, data careers, and ethnographies in the laboratory with Couch’s democratic vision. I contextualize this vision in light of a particular representative-constituent study (RCS) which served as a metaphor for Couch’s pragmatic outlook.
Early changes in material properties of rabbit articular cartilage after meniscectomy

We have correlated early material and biochemical changes in articular cartilage in a surgical model for cartilage degeneration. Medial meniscectomy was performed on the left knee of 17 adult, female New Zealand white rabbits. The equilibrium Young's modulus of cartilage was assessed by an indentation test in situ at defined sites on the medial and lateral tibial plateaus of the operated and control knees; the cartilage was then excised and analyzed biochemically. Focal changes were consistently observed in the medial surface of the operated knee. The equilibrium modulus and the glycosaminoglycan content fell rapidly, reaching a minimum by 2 weeks after surgery; the lateral tibial surface was essentially unaffected. Six months after surgery, the glycosaminoglycan content had returned to normal and the modulus to near normal. Independent measurements on cored plugs from the medial surface 2 weeks after surgery revealed a significant decrease in both the dynamic stiffness and the streaming potential in the operated knee compared with the control. The findings suggest that normal ambulatory loads in vivo will deform the affected medial cartilage much more than normal. It remains to be seen if altered mechanical stresses are solely responsible for initiating and sustaining matrix remodeling by the chondrocytes.
Anterograde Transvenous Balloon Angioplasty of Recurrent Coarctation in Infancy

Balloon angioplasty of a severe recurrent coarctation was performed in a 4-month-old infant using an anterograde approach not previously described for this lesion. The entire procedure was performed transvenously. After transseptal entry into the left atrium, the transseptal sheath was placed across the mitral valve and the angioplasty catheter advanced across the recurrent coarctation. Angioplasty reduced the systolic gradient from 65 mmHg to 22 mmHg, without acute complications. We feel that the anterograde transvenous approach should be considered as an alternative to retrograde transarterial angioplasty in infancy, since femoral artery injury is avoided. (J Interven Cardiol 1988:1:2)
Effect of a non-thermal, atmospheric-pressure, plasma brush on conversion of model self-etch adhesive formulations compared to conventional photo-polymerization.

Objective To determine the effectiveness and efficiency of non-thermal, atmospheric plasmas for inducing polymerization of model dental self-etch adhesives.
Hospital - Based Accelerator for Proton Radiotherapy

The rationale for designing a dedicated hospital-based proton accelerator for therapy is reviewed and the specifications for such a machine are given. The main parameters of a suitable conventional proton synchrotron are listed, and certain aspects (main magnet, choice of lattice, choice of proton source and RF system) are discussed in somewhat more detail. Important areas of the design, such as the extraction system, remain to be finished, but there is reason to hope that such a machine could be designed to sell for a few million dollars. This would make protons available to complement photons in radiotherapy.
Photoinduced electron transfer from Ru am(m)ine compounds with low-lying ligand field excited states to nanocrystalline TiO2

Abstract The coordination compounds [Ru(NH 3 ) 5 (eina)](PF 6 ) 2 , [Ru(NH 3 ) 4 (deeb)](PF 6 ) 2 and [Ru(en) 2 (deeb)](PF 6 ) 2 , where eina is ethyl isonicotinate, deeb is 4,4′-(CO 2 CH 2 CH 3 ) 2 -2,2′-bipyridine and en is ethylenediamine, were synthesized and characterized. [Ru(NH 3 ) 4 (deeb)](PF 6 ) 2 ·2CH 3 COCH 3 and [Ru(en) 2 (deeb)](PF 6 ) 2 ·CH 3 COCH 3 single crystals were characterized by X-ray crystallography. Near-infrared photoluminescence was observed after photoexcitation of [Ru(en) 2 (deeb)](PF 6 ) 2 in butyronitrile at 77 K. The excited states of these compounds were found to be short-lived in fluid solution and when anchored to mesoporous nanocrystalline (anatase) TiO 2 thin films immersed in CH 3 CN at room temperature, consistent with excited-state lifetimes 2 films immersed in CH 3 CN resulted in a loss of the metal-to-ligand charge transfer (MLCT) absorption that was attributed to ligand-field photochemistry. Pulsed 532 nm light excitation of the compounds anchored to TiO 2 thin films yielded an interfacial charge-separated state, i.e. Ru III /TiO 2 (e − ), that formed within 10 ns and returned cleanly to the initial Ru II /TiO 2 state on a micro- to milli-second time scale. Quantum yields for formation of this state determined by comparative actinometry were excitation wavelength dependent suggesting the involvement of “hot” MLCT excited states. The quantum yields were also dependent on acid/base pre-treatments of the TiO 2 surface. Photoelectrochemical performances of [Ru(NH 3 ) 4 (deeb)](PF 6 ) 2 and [Ru(en) 2 (deeb)](PF 6 ) 2 on TiO 2 in regenerative solar cells were consistent with excitation-wavelength-dependent electron injection.
Secretion Rates of Thyroxine and Triiodothyronine in Dairy Cattle

Abstract Thyroid hormone secretion rates (TSR) were determined in 7 lactating dairy cows by the substitution method (suppression of thyroidal 131 I release) and averaged .21mg L-thyroxine (L-T 4 ) equivalents per 45.4kg body weight per day. In the same animals, TSR for thyroxine (T 4 SR) and for triiodothyronine (T 3 SR) were determined separately by the radioiodine labelled hormone pool turnover method. Pool sizes in the 7 cows were 36.9 liters (8.27% of body size) for L-T 4 and 107.1 liters (22.1% of body size) for l-triiodothyronine (L-T 3 ) when no goitrogen was given but were increased to 56.0 liters (12.2% of body size) for L-T 4 and 201.0 liters (41.5% of body size) for L-T 3 when the goitrogen methimazole (tapazole) was given orally at 4g per 454kg body weight per day (P 4 and L-T 3 in the absence of goitrogen and 1.59 and 1.02 with goitrogen. Concentration of L-T 4 in the plasma pool was 7.49 μ g per 100ml without the goitrogen and 6.18 μ g per 100ml with it while the concentration of L-T 3 in the plasma pool, measured in the absence of goitrogen treatment only, was .149 μ g per 100ml. Mean T 4 SR in the 7 cows was .143mg per 45.4kg body weight per day without a goitrogen and .148mg in the presence of the goitrogen; T 3 SR was .0139mg without methimazole and .0193 with it. If L-T 3 is 2.1 times as effective as L-T 4 in suppressing 131 I release by the thyroid, the combined TSR of L-T 3 and L-T 4 without a goitrogen would be .172mg of L-T 4 equivalents per 45.4kg body weight per day and .189mg with the goitrogen. On this basis the substitution method overestimates TSR in cattle by 12 to 22%. Correlation coefficients for TSR with milk production were positive but low and nonsignificant, varying from .64 to zero and being .30 in 39 comparisons.
Heart rate changes in convulsive and nonconvulsive neonatal apnea

One hundred twelve apneic spells of at least 4 seconds' duration were monitored in 15 neonates; 77 episodes were associated with convulsive discharges on the electroencephalogram and 35 were not. Convulsive apnea did not occur in conjunction with bradycardia. Nonconvulsive apnea of less than 20 seconds' duration occurred in the presence of variable heart rates, but nonconvulsive apnea of 20 seconds or longer was nearly always associated with bradycardia.
Integrated Sibling-Parent Group Intervention to Improve Sibling Knowledge and Adjustment to Chronic Illness and Disability

Objective: To evaluate an integrated group intervention for siblings and parents designed to increase sibling understanding of and adjustment to chronic illness and developmental disability (CI/DD). Methods: Fifty-four well siblings (ages 8‐13 years) and their parents were recruited through hospital-based and community agencies serving children with CI/DD. Measures of sibling knowledge, sibling adjustment to the disorder, sibling connectedness, and sibling global behavioral functioning were collected before and after the intervention. A subsample of 20 families completed a 3-month follow-up to assess maintenance of results. Results: Sibling knowledge of the child’s disorder and sibling connectedness increased, while sibling reports of negative adjustment to the disorder and parent reports of sibling global behavioral functioning decreased significantly from pre- to posttreatment for both boys and girls, regardless of the type of diagnostic condition. Improvements in sibling knowledge, connectedness, and behavioral problems maintained at 3-month follow-up. Parent satisfaction with the program was high. Conclusions: Results support the future conduct of more controlled evaluation of the integrated sibling and parent group intervention model to improve sibling knowledge of and adjustment to CI/DD.
Ecological factors underlying the adrenocortical response to capture stress in arctic-breeding shorebirds.

Birds breeding in the Arctic must carefully balance survival and reproduction because of the often extreme environmental conditions and the very brief breeding season. Acute elevation of plasma corticosterone is one mechanism that birds apparently use to alter the balance in favor of survival at the expense of reproduction when faced with stressors such as storms, predators, or low food availability. To examine this relationship, we applied a standardized stressor, capture and handling, to four species of shorebirds (Scolopacidae) during their breeding season in the Arctic and measured the increase in corticosterone between 3 min and 30 min after capture (hereafter called the stress response). We tested two hypotheses in an effort to explain the individual variation observed in the stress response. The first hypothesis states that individuals most responsible for parental care have a lower stress response than individuals less responsible for parental care. In species with uniparental care (Pectoral Sandpiper Calidris melanotos, Red Phalarope Phalaropus fulicaria), the caregivers had a lower stress response than the opposite sex, although in the latter species the difference was not significant (P = 0.016 and P = 0.102, respectively). In a species with equal biparental care (Semipalmated Sandpiper C. pusilla), the stress response did not differ between the sexes (P = 0.99, Barrow population). In a species with unequal biparental care (Western Sandpiper C. mauri), the more parental sex (males) had a much lower stress response than the less parental sex (P = 0.002). The second hypothesis states that individuals breeding in the high Arctic have a lower stress response than individuals breeding in the low Arctic. The stress response in a low-Arctic population of Semipalmated Sandpipers (Nome) was higher than that in a high-Arctic population (Barrow, P 0.05). Taken together, these results provide evidence of a mechanism that birds may use to breed in environments with a brief breeding season and under conditions that might be perceived as stressful, if not for their reduced sensitivity to potential stressors.
LOSS OF GREEN COLOR OF REFRIGERATED AND NONREFRIGERATED SOUTHERN PEAS

Southern pea quality is judged commercially according to USDA grading standards. The presence of green color determines USDA grades of Southern peas. Since USDA testing procedures are subjective in nature and the objective of this investigation was to provide commercial Southern pea processors a practical means of preserving pea color, it was determined that measurements should be made subjectively to give validity to the results. This study shows that Grade A peas can be maintained by hydrocooling and holding them under refrigeration subsequent to the harvesting and shelling operations.
Malignant gliomas: strategies to increase the effectiveness of targeted molecular treatment

Recently, there has been increasing interest in the use of targeted molecular agents for the treatment of malignant gliomas. These agents are generally well tolerated but have demonstrated only modest activity. In this article, the current status of targeted molecular agents for malignant gliomas will be reviewed and strategies to improve their effectiveness will be discussed.
The Value of Pelvioradiography in the Management of Dystocia

Summary A series of 280 obstetric cases in which dystocia was expected were studied by pelvioradiography as an aid in determining the obstetrical prognosis and treatment. The cases were classified in four groups: no disproportion, borderline, relative, and absolute disproportion; and the prognosis was good, fair, guarded and poor, respectively. Treatment recommended was based on the above considerations. 1. The roentgen prognosis was correct in 97.9 per cent. 2. As the prognosis became worse the incidence of operative deliveries increased. 3. Cesarean section was necessary for good results when poor prognosis was given by x-ray pelvimetry. 4. In 52 cases in which cesarean was considered likely, it was performed in 41 and should have been performed in 7 more as indicated by disastrous results following vaginal delivery. 5. The conservative influence of pelvioradiography in a dystocia series was shown by the fact that only 114 or 40 per cent required operative delivery. 6. The android and platypelloid pelves were frequently found among the cases in which poor prognosis was given. 7. he anthropoid pelves were all given a favorable prognosis, and subsequent events proved this confidence justified. 8. The gynecoid pelvis was the most difficult to evaluate correctly and the size of the pelvis was often the chief guide. There was an increase in operative deliveries in the following order: anthropoid, gynecoid, platypelloid and android. 9. Half of the stillbirths could have been avoided if the radiologic advice had been followed. 10. The cesarean operation was more accurately limited to those cases in which it was essential.
A Note on REIT Returns and the Case-Shiller Home Price Index

In this note, we examine the relationship between real estate investment trust (REIT) returns and the Case-Shiller Home Price Index using panel data on 159 unique REITs over the 25-year period of 1...
Application of analytical methods to computing numerical flux Jacobians

Overview This paper compares the accuracy, convergence, and performance of two different methods for determining numerical flux jacobians for the ideal MHD (magnet ohydrodynamic) equations. This paper's algorithm is a Roe approximate Riemann solver. The numerical flux jacobian is the derivative of the flux with respect to the conserved variables. Implicit solvers, which use a form of Newton iteration, use numerical flux jacobians to find the correct solution. This paper uses two methods to formulate the numerical flux jacobian. The limit formulation perturbs each conserved variable and measures the change in the flux. The analytic formulation evaluates the analytic derivative for the numerical flux. A similar comparison for the Navier-Stokes equations has been published by Orkwis and Venden, that paper suggests that the analytic formulation may be futile effort. This paper reassesses this judgement. The accuracy and convergence of the two methods are identical. The analytical formulation requires less computational time than the limit formulation. This paper describes the algorithm and theory involved. It presents the results from a solver that implements both methods.
"Fit Between CEAI Measures, Strategic, and External Factors"

The Corporate Entrepreneurship Assessment Instrument (CEAI) has four dimensions that have been shown to be valid measures of the internal antecedents of corporate entrepreneurship. Previous researc...
Landscape as Cartography in Early Christian Pilgrimage Narratives

L'A. s'interesse a la geographie des pelerinages chretiens en destination de la Terre Sainte : pour ce faire, il se fonde sur les recits de voyage laisses par les pelerins tout au long de l'histoire (a partir du IV e siecle). Il prend l'exemple du pelerin de Bordeaux en premiere partie. La seconde partie est consacree au recit d'Egeria (380 en Terre Sainte). Les recits de Jerome occupent la partie suivante. Apres l'examen d'un dernier temoignage l'A. tire des considerations generales pour conclure
Bullying behind bars: a preliminary study of human resources professionals and workplace bullying in corrections

Purpose – The purpose of this paper is to investigate the prevalence of workplace bullying reported to human resources (HR) professionals in corrections. It compared the prevalence of bullying reported to HR professionals to the prevalence of self-reported workplace bullying found in the study by Einarsen et al. (2009). Design/methodology/approach – In total, 75 HR professionals completed the modified version of the Negative Acts Questionnaire – Revised (The Bergen Bullying Research Group, 2009) that consists of three subscales measuring work-related bullying, person-related bullying, and physically intimidating bullying. Participants indicated how often certain types of workplace bullying were reported to them. The prevalence of bullying reported to HR professionals was then compared to the prevalence of self-reported workplace bullying found in the comparison study. Findings – The findings of the study were statistically significant and demonstrated that more workplace bullying was reported to HR profes...
Sound Therapy-Based Treatment to Expand the Auditory Dynamic Range.

I am excited to introduce you to this unique edition of Seminars in Hearing. Rather than a group of articles on a topic, you will find a comprehensive article outlining a recently completed study by Dr. Formby and his colleagues. This is the first study to be produced that provides a randomized placebo-controlled clinical trial investigating sound therapy–based intervention to expand the auditory dynamic range. At a time when we continue to see very few randomized controlled trials in audiology, we are pleased to be able to provide you with this comprehensive report. Dr. Formby and his colleagues have used the Seminars in Hearing format so they can provide extensive details about the study including how the placebo sound generator was envisioned and created. There is an entire appendix devoted to the specifics of the placebo condition for those interested or in a position to replicate or continue this important work.
Recurrent adult myofibromatosis. A case report.

Myofibromatosis generally is regarded as a fibrous proliferative disease of neonates and children that, even when multicentric, has an excellent prognosis and a propensity for spontaneous involution. Reported is a case of solitary, locally recurrent myofibromatosis in the ear canal of an adult patient. It was initially thought to be a leiomyoma. The diagnosis of myofibromatosis was made on the basis of its histologic appearance and corrob orated by immunohistochemical stains. Clinicians and pathologists should be aware that myofibromatosis may occur in adults in unusual locations, with a potential for local recurrence. Furthermore, its histologic appearance may mimic that of other mesenchymal neoplasms.
Analysis on the epidemiological characteristics of measles,Weifang city,2013-2014

Objective To understand the epidemic situation of measles in Weifang city,so as to provide scientific basis for the measles elimination strategies. Methods Descriptive epidemiology method was applied to explore the epidemic regularity of measles in Weifang city,2013-2014. Results During 2013-2014,a total of 346 cases of confirmed measles were reported in Weifang city,with the annual average incidence rate of 1.87/105,without death cases.The epidemic peaks of measles were from March to August,accounting for 94.80%(328/346)of the total cases.Most cases were concentrated in Anqiu,Kuiwen,Shouguang,and Fangzi cities(districts),accounting for 65.90%(228/346)of all cases.The age of these patients ranged from 3months to 62 years,in which a great majority were children between 0-5years old and adults aged 20-50 years old,accounting for 39.60%(137/346)and 52.31%(181/346)of the total cases respectively.Most occupations of measles patients were scattered children,farmers,and worker,accounting for 37.57%(130/346),24.57%(85/346),and7.51%(26/346)of the total cases respectively.61 cases had the history of measles vaccine immunization,48 cases had no immunization history,and 237 cases had unknown history.2 measles outbreaks were in Anqiu and Shouguang cities,respectively. Conclusion The incidence rate of measles has a gradual upward trend in Weifang city,2013-2014.Most cases are children aged 0-5years old and adults aged 20-50 years old.
ON THE ARCUATE STRUCTURES AND THEIR ORE-CONTROLLING SIGNIFICANCE

Arcuate structures belong to rather special geological structure type resulted from rotation and shearing movement, which are occurred in the special gradual variation stress field. They have clear deformational zonation, rock and ore controling function and can provide the boundary condition of homothetic metallogenesis as a macroscopic formation mechanism of the large superlarge ore deposit. Some problems about rock and ore controlling function of arcuate structures and metallogenetic prognosis concerned, especially in the "Three River"area of Southwest China, are discussed in this paper.
Complete hematologic remissions induced by 2-chlorodeoxyadenosine in children with newly diagnosed acute myeloid leukemia

The majority of children with acute myeloid leukemia (AML) who are treated exclusively with chemotherapy die of progressive disease. Improvement in outcome will likely require new active drugs capable of eradicating resistant blast cells early in the clinical course. We therefore assessed the cytoreductive potential of 2-chlorodeoxyadenosine (2-CdA), a halogenated purine analogue, in 22 consecutive children with newly diagnosed AML. The drug was administered as a single 120-hour continuous infusion (8.9 mg/m2 of body surface area per day) before the introduction of standard remission induction therapy. Six patients (27%) had complete hematologic remissions by a median of 21 days after treatment with the nucleoside (range, 14 to 33 days). Seven others had partial responses, yielding a total response rate of 59%. The drug also eliminated leukemic cells from cerebrospinal fluid in 4 of the 6 patients tested. Concentrations of 2-CdA in cerebrospinal fluid on day 5 after the initiation of treatment ranged from 12.4% to 38.0% (mean, 22.7%) of the steady-state plasma concentrations. Severe but reversible myelosuppression and thrombocytopenia developed in all patients. Analysis of factors that may have influenced the complete remission rate suggested a better outcome in patients with myeloblastic leukemia (M0-M2 subtypes in the revised French-American-British classification system). These results demonstrate clinically significant activity by 2-CdA against previously untreated AML in children, including leukemic blast cells in the central nervous system. Its use in combination chemotherapy may improve the outlook for patients with this often fatal hematologic cancer.
The effect of physical training on the serum iron levels of college-age women.

Physical training in women has been found to be associated with a significant decrease in serum iron levels suggesting a state of deteriorating iron stores. To further study this phenomenon, seventeen women, aged 19 to 23 years, volunteered to participate in a 10-week physical training program to study the effect of training on serum iron levels. The training consisted of three 20-25 minute exercise bouts per week on a bicycle ergometer with individual workloads equivalent to approximately 70% of each subject's maximum aerobic capacity. Additionally, eight women, aged 19 to 28, volunteered to act as a control group. Assessments of hemoglobin (Hb), hematocrit (Hct), serum iron (SeFe), and maximum oxygen uptake (Vo2 max) were made on both groups prior to and at the conclusion of the training period. Upon completion of training, Vo2 max (ml/kg/min) increased by eleven percent (p less than .05) whereas Gb and Hct showed no significant changes for the trainign group with respect to the control group. Se Fe levels (microgram/100ml) in the training group did not differ significantly from those of the control group in both pre-training (128.8 +/- 7.6 vs 103.7 +/- 13.7, X +/- SE) and post-training (126.6 +/- 7.9 vs. 120.9 +/- 16.3, X +/- SE) conditions. Neither day of menstrual cycle nor use of oral contraceptives nor use of iron supplements was found to have any systematic effect on SeFe levels. The results suggest that short term physical training in college-age women does not significantly lower SeFe levels.
Ankle Morel-Lavallée lesion in a recreational racquetball player

Unilateral ankle swelling is a relatively common presenting complaint among athletes and non-athletes. Due to its broad differential diagnosis, a comprehensive evaluation beginning with history and physical examination are recommended. Imaging including plain radiography, ultrasound (US), and magnetic resonance imaging (MRI) are preferred modalities. Aspiration of a local fluctuating mass may help with the diagnosis and management of some of these conditions. Morel-Lavallee lesion (MLL) is a rare condition consisting of a closed degloving injury caused by forces of pressure and shear stress between the subcutaneous tissue and the superficial fascia or bone. Most commonly MLL is found over the greater trochanter and sacrum, but in rare cases can be found in other regions of the body. In most cases concurrent severe injury mechanisms like motor vehicle accidents are present. MLL due to sports injuries are rare. Depending on the stage and type of MLL, therapeutic strategies may vary from compression wraps and aspiration to surgical evacuation. We present a case of a 65-year-old gentleman with ankle MLL with no known history of a major trauma as a result of playing racquetball 6 weeks earlier. Physical examination revealed a transilluminating lesion in the lateral aspect of his left ankle which was successfully treated with one time aspiration of a serosanguinous fluid. We propose less aggressive methods for management of low-impact sports-related MLL.
Has market concentration fostered on-time performance? A case study of seventy-two U.S. airports

Abstract The study compares a multivariate with a quantile regression model to determine whether utilized airport capacity, departure and airborne delays, departure and arrival demand, and market structure explained variations in on-time gate arrivals and arrival delays. In both models, airport departure delays, arrival and departure demand explained variations in the two response variables in prioritized and non-prioritized metroplexes, holding other variables constant. After 2008, the consolidation of the airline industry through mergers coincided with the implementation of NextGen programs, which may have contributed to improvements in on-time performance, especially at prioritized metroplexes where airspace was redesigned.
Bottom-up proteomics analysis of the secretome of murine islets of Langerhans in elevated glucose levels.

Glucotoxicity is a causative agent of type-2 diabetes, where high glucose levels damage the islets of Langerhans resulting in oxidative damage and endoplasmic reticulum stress. We evaluated the secretomes of healthy CD-1 murine islets. Three experimental conditions were investigated in biological triplicate: a control incubated with 11 mM glucose, 1-day incubation with 25 mM glucose, and 2-day incubation with 25 mM glucose. An SDS-based, filter-aided sample preparation protocol was used to prepare secretomes for analysis. A total of 428 protein groups were identified across the nine samples. Each condition generated between 328–349 protein IDs and intracondition protein overlap was between 66–90% for the biological triplicates. 232 protein groups were identified in all three conditions with 184 quantified at least once in each condition. Significant expression changes were observed for proteins associated with the unfolded protein response, such as proteases, chaperones, and elongation factors, as well as proteins associated with peptide hormone processing and small molecule metabolism.
Electrically Pumped Photonic Crystal Lasers

Visible electrically pumped 2-D photonic crystal lasers were fabricated within membranes of InGaP /InGaAlP quantum well material which has the PIN diode structure incorporated. They're the first current driven lasers with ultrasmall mode volumes.
Compliance with research standards within gynecologic oncology fellowship: A Gynecologic Oncology Fellowship Research Network (GOFRN) study

Abstract Objectives Participation in clinical and basic science research is emphasized in gynecologic oncology training. We sought to identify trends in adherence to expected research practices and reasons for non-adherence among gynecologic oncology fellows. Methods An anonymous 31-question online survey assessing academic behaviors, including IRB compliance, authorship assignment, data sharing, and potential barriers to non-adherence was distributed to all SGO gynecologic oncology fellow members in July 2016. Descriptive statistics and univariate analyses were performed. Results Of 190 members, 35.3% (n=67) responded. 73% (n=49) of respondents reported personal non-compliance and 79.1% (n=53) reported having witnessed others being non-complaint with at least one expected research practice. Areas of compliance failure included changing a research question without appropriate IRB amendment (20%; n=14), conducting research under a nonspecific IRB (13.9%; n=9), and performing research without IRB approval (6.1%; n=4). Longer institutional time for IRB approval was significantly associated with IRB non-adherence (p 1000 patients. Thirty respondents (45.5%) assigned authorship to someone who failed to meet ICMJE criteria and twelve (18.5%) accepted authorship without meeting ICMJE criteria. Most commonly cited reasons for non-adherence were: cumbersome IRB processes (80.3%), pressure from senior authors (78.8%), fear of someone else publishing first, (74.2%) and lack of support navigating appropriate research practices (71.2%). Conclusions Fellow non-compliance with expected research practices is high, particularly with regards to secure storage of PHI and appropriate authorship assignment. Time-consuming and cumbersome IRB procedures, perceived pressure from senior authors, and lack of research support contribute to non-adherence. Further support and education of gynecologic oncology fellows is needed in order to help address these barriers.
A 127mW 1.63TOPS sparse spatio-temporal cognitive SoC for action classification and motion tracking in videos

A sparse spatio-temporal (ST) cognitive SoC is designed to extract ST features from videos for action classification and motion tracking. The SoC core is a sparse ST convolutional auto-encoder that implements recurrence using a 3-layer network. High sparsity is enforced in each layer of processing, reducing the complexity of ST convolution by two orders of magnitude and allowing all multiply-accumulates (MAC) to be replaced by select-adds (SA). The design is demonstrated in a 3.98mm2 40nm CMOS SoC with an OpenRISC processor providing software-defined control and classification. ST kernel compression is applied to reduce memory by 43%. At 0.9V and 240MHz, the SoC achieves 1.63TOPS to meet the 60fps 1920×1080 HD video data rate, dissipating 127mW.
Exposure to light-emitting diodes may be more damaging to the sensory properties of fat-free milk than exposure to fluorescent light

ABSTRACT Light exposure can damage the sensory properties of milk, leading to adverse consumer responses. This is presumed to be through the action of photosensitive compounds such as riboflavin, present in milk and capable of releasing energy when irradiated, leading to damage of proteins and fats in the milk. Light-emitting diode (LED) lighting is assumed to be less damaging to milk due to lower inherent power consumption. In this study, fat-free milk was exposed to LED and fluorescent light at 2,000 lx to compare the sensory thresholds of exposure, the flavor profile of milk produced by these exposures, and resultant consumer acceptance of the samples. Additionally, the effectiveness of light-protective packaging and supplementation with antioxidants was evaluated. The sensory threshold from LED exposure was no longer than from fluorescence, whereas with antioxidants (tocopherols and ascorbic acid), the majority of the panelists failed to discriminate milk exposed to LED light even at 48 h of exposure. Trained panelists described light-exposed milk as significantly higher in cardboard, old oil, and plastic, with LED exposure resulting in a marginally more plastic aroma, and fluorescent marginally more cardboard. Consumers reported higher liking for fluorescent-exposed samples versus those exposed to LED. The antioxidant-supplemented samples, and those exposed to LED light engineered to eliminate wavelengths below 480 nm (thus most of riboflavin's absorption peaks), resulted in significantly higher old oil aroma; however, the former received higher liking scores than LED-exposed samples. Light-protective packaging offered near-complete protection from LED exposure, with a similar flavor profile as unexposed milk, and the best liking scores of any treatment. Nevertheless, consumers disliked its appearance, due to unfamiliarity, suggesting some consumer education may be needed if this were to be an efficient protective strategy.
Student Video Viewing Habits in an Online Mechanics of Materials Engineering Course

This paper investigated the video viewing habits of students in a sophomore-level, online Mechanics of Materials (MoM) course offered in Spring 2017 and how those habits affected student course grades. Data on student engagement and viewership were collected from a MoM course through a learning management system. This data was compared with length of videos, video content, and video types. With viewership being the focus of the study, it was determined that student engagement decreased over the semester, the content of a video affected its viewership, and viewing rates fluctuated depending on the exam. The other finding was that an increase in viewership tended to indicate an improvement in students’ grades. While the videos are an effective means of improving students’ course grade, changes could be made to improve the videos and increase engagement.
Abstract 1868: Real-Time Three-Dimensional Echocardiographic Evaluation of Prosthetic Valves: Initial Experience with a Matrix Transesophageal Transducer

Background. Echocardiographic evaluation of prosthetic valves may be confounded by the inability to obtain en-face views with optimal resolution. 2D scanning with a multiplane probe and subsequent ...
An Historical Perspective on ‘Linguistic Relativity’

What is now commonly called the “principle of linguistic relativity” asserts a correlation between language and thinking either with regard to the specifics, the structure, the categories, or some other generalities of each. In its stronger form, it postulates that in some way the language of any given culture is the causal determinant of the patterns of thinking in that culture. In still another variation, “linguistic relativity calls attention to differences in cultural pattern, and to their importance for linguistic experience and.behavior” (Hymes, 1966, p. 114), or language and culture are viewed as reciprocally or co-determined. The principle is now best known from the works of Edward Sapir [1884–1939], professor of anthropology and linguistics in the Universities of Pennsylvania, Chicago, and Yale, and Benjamin Lee Whorf [1897–1941], a fire-prevention engineer in Hartford, Connecticut, by profession and a linguist by passionate avocation. The pertinent works were composed mainly during the 1920s and 1930s, and the hypothesis reached a broader audience through publication of collected essays by both men during the 1950s. It was then that the position received more extensive discussion, criticism, and evaluation by anthropologists, linguists, psychologists, and philosophers. Similar hypotheses have been recurrent in the history of the philosophy of language since the eighteenth century
Do Estimates of Treatment Risk Based on Clinical Vignettes Differ by Physician Gender

Background Clinical vignettes are frequently used as instructional and evaluative instruments for physicians. Physicians’ gender is a source of unconscious bias in treatment recommendations. This study assessed whether interpretation of information in clinical vignettes differed by physicians’ gender as a possible source of unconscious bias. Methods Thoracic surgeons and physicians in cardiothoracic surgical training were asked to provide estimates of major complication rates for lung resection on the basis of anonymized clinical vignettes of patients undergoing lung resection. Vignettes were categorized as low, average, and high risk by using a sum of Charlson Comorbidity Index (possible range, 0 to 37) and a combined physiologic score, EVAD (forced expiratory volume in 1 second, diffusing capacity of lung for carbon monoxide, age; possible range, 0 to 12); participants were not aware of the risk scores or vignette categories. Generalized estimating equation linear regression models were fit with risk scores treated as a continuous independent variable. Results A total of 247 physicians (105 practicing surgeons, 142 trainees; 203 men, 44 women) participated in one or more of the studies. Nearly all (103; 98%) of the practicing surgeons rated themselves as competent or expert in lung resection compared with 77 (54%) of the trainees (p Conclusions Unconscious bias related to physicians’ gender is not associated with differential use of information in clinical vignettes. Any possible bias may arise from face-to-face interactions with patients. Research into physicians’ and patients’ gender differences during such interactions is warranted.
Water retention measurement for soils.

A method for rapidly obtaining water retention data for soils is presented. A variation of the Richard’s pressure cell is used in which equilibrium at a particular water content is achieved by adjustment of the outflow pressure, rather than by permitting equilibrium to be reached at a fixed increment of water pressure. On the wetting cycle, water is added directly to the sample rather than being imbibed through the capillary barrier. The result is that data on both wetting and drying cycles can be obtained in a small fraction of the time needed for conventional procedures. Consistent data which fit on a smooth curve have been obtained. The results are thought to be comparable to those determined by the Richards procedure except, possibly, in a range of water contents greater than that at which an interconnected air phase exists.
Dosimetric study on learning-based cone-beam CT correction in adaptive radiation therapy

Abstract Introduction Cone-beam CT (CBCT) image quality is important for its quantitative analysis in adaptive radiation therapy. However, due to severe artifacts, the CBCTs are primarily used for verifying patient setup only so far. We have developed a learning-based image quality improvement method which could provide CBCTs with image quality comparable to planning CTs (pCTs). The accuracy of dose calculations based on these CBCTs is unknown. In this study, we aim to investigate the dosimetric accuracy of our corrected CBCT (CCBCT) in brain stereotactic radiosurgery (SRS) and pelvic radiotherapy. Materials and Methods We retrospectively investigated a total of 32 treatment plans from 22 patients, each of whom with both original treatment pCTs and CBCTs acquired during treatment setup. The CCBCT and original CBCT (OCBCT) were registered to the pCT for generating CCBCT-based and OCBCT-based treatment plans. The original pCT-based plans served as ground truth. Clinically-relevant dose volume histogram (DVH) metrics were extracted from the ground truth, OCBCT-based and CCBCT-based plans for comparison. Gamma analysis was also performed to compare the absorbed dose distributions between the pCT-based and OCBCT/CCBCT-based plans of each patient. Results CCBCTs demonstrated better image contrast and more accurate HU ranges when compared side-by-side with OCBCTs. For pelvic radiotherapy plans, the mean dose error in DVH metrics for planning target volume (PTV), bladder and rectum was significantly reduced, from 1% to 0.3%, after CBCT correction. The gamma analysis showed the average pass rate increased from 94.5% before correction to 99.0% after correction. For brain SRS treatment plans, both original and corrected CBCT images were accurate enough for dose calculation, though CCBCT featured higher image quality. Conclusion CCBCTs can provide a level of dose accuracy comparable to traditional pCTs for brain and prostate radiotherapy planning and the correction method proposed here can be useful in CBCT-guided adaptive radiotherapy.
An Energy-Efficient Intrusion Detection System for MANET

In the present scenario, the technology of wireless ad hoc networks has gained a lot of importance. Mobile ad hoc network (MANET) is an area that belongs to ad hoc wireless network. Nodes in mobile network have small batteries with limited power. The huge numbers of mobile nodes in MANET makes it impractical to replace sensor node batteries. Along with that, it has open medium and wide distribution of nodes that make MANET open to various types of attacks. Thus, to handle these various types of attacks, it is essential to make a competent and secure network in MANET. Thus, the lifetime of Mobile nodes is a significant attribute of wireless ad hoc networks with proper security norms. In this paper, an energy-efficient Cluster-based Game IDS Protocol for routing over MANET is proposed. In the field of network security, various techniques have been proposed but having disadvantages over power consumption. In order to overcome all these disadvantages of the proposed, Cluster-based game theory for IDS has been proposed that integrates the Game theory and K-means. In the proposed methodology, game theory is used to calculate reliability score, where K-means provide scope of reliability score up to a cluster with specific cluster head. This approach helps to enhance security with network survival. The simulation results also provide the enhanced outcome on comparison with the previous applied techniques.
Toward Coherent Control of Single Yb 3 + Ions in a Nanophotonic Cavity

We report on detection and coherent optical driving of single Yb3+ ions coupled to a nanophotonic resonator fabricated in the YVO 4 host crystal and outline a path toward control of single 171 Yb3+ spins. © 2019 The Author(s)
Hamstring Muscle Activity After Primary Anterior Cruciate Ligament Reconstruction—A Protective Mechanism in Those Who Do Not Sustain a Secondary Injury? A Preliminary Study:

Background:Individuals who experience a subsequent ipsilateral anterior cruciate ligament (ACL) reinjury may use hazardous muscle activation strategies after primary ACL reconstruction (ACLR). The ...
Clinical Manifestations of Insulin Resistance in Youth

The ongoing obesity epidemic places about a third of American youth at risk for developing obesity-related insulin resistance. This is manifested by reduced multiorgan effects of insulin, leading to elevated insulin concentrations and, in some cases, inappropriately elevated glucose and lipid concentrations. Many risk factors for insulin resistance—including genetics, epigenetics, obesity, diet, and lifestyle—are in common between adolescents and adults. However, adolescents have a unique risk factor in the physiologic insulin resistance of puberty, which along with obesity can pose a “double hit” to the beta-cell, causing increased burden for insulin secretion.
Heterogeneity in Risk and Protection Among Alaska Native/American Indian and Non-Native Children

Currently, little is known about patterns of co-occurring risk and protective factors among young children. Understanding variations in co-occurring risk and protective factors among children in Alaska is important as experiences of collective trauma may contribute to differences in the intersection of risk and protective factors between Alaska Native/American Indian (AN/AI) and non-Native children. Using data from the Alaska Longitudinal Child Abuse and Neglect Linkage (ALCANLink) project, a linkage of the 2009–2011 Alaska Pregnancy Risk Assessment Monitoring System survey and administrative data sources, and the 2012–2014 Childhood Understanding Behaviors Survey, we conducted latent class analysis to identify classes of AN/AI (N = 593) and non-Native (N = 1018) children in terms of seven risk factors (poverty, maternal depression, maternal binge drinking, parental incarceration, intimate partner violence exposure, other violence exposure, child maltreatment) and four protective factors (father figure involvement, reading by adults, family meals, peer interactions) experienced prior to age 3 years. We identified two classes among AN/AI children: (1) high risk-moderate protection (29.1%) and (2) low socioeconomic status-high protection (70.9%). We identified two classes among non-Native children: (1) moderate risk-high protection (32.9%) and (2) low risk-high protection (67.1%). A test of invariance revealed that risk and protective factor probabilities differed significantly for corresponding classes of AN/AI and non-Native children. Overall, results demonstrate heterogeneity within and between AN/AI and non-Native children in early experiences of risk and protection and suggest that interventions will be more effective if tailored to the experiences and developmental needs of specific groups of Alaska children.