cssi/SciSciGPT-SciSciNet huggingface dataset:
Getting to Know the Child with Asperger Syndrome

Asperger syndrome (AS) is a disorder characterized by social skill deficits and display of repetitive behaviors. This article explores the diagnostic components of AS and describes the major school...
Reversal of optic canal stenosis in osteopetrosis after bone marrow transplant

Abstract PURPOSE: To describe a patient with infantile osteopetrosis and optic atrophy secondary to optic canal stenosis who demonstrated optic canal enlargement after bone marrow transplant. METHODS: Case report. A 3-month-old infant with infantile “malignant” osteopetrosis underwent ophthalmic examination, including visual evoked potentials, electroretinogram, and computed tomography (CT). Bone marrow transplant was performed at 8 months of age. RESULTS: Examination revealed visual loss and optic atrophy, left eye greater than right eye, secondary to optic canal stenosis. Flash visual evoked potentials revealed a normal waveform in both eyes with increased latency in the left eye. Electroretinogram was normal in both eyes. CT after bone marrow transplant showed enlargement of the optic canals. Vision remains stable 43 months after bone marrow transplant. CONCLUSIONS: Bone marrow transplant in infantile osteopetrosis may be followed by reversal of optic canal stenosis and preservation of vision.
Developing past and future selves for time travel narratives

Mental time travel requires the sense of a past and future self, which is lacking in the early years of life. Research on the development of autobiographical memory and development of self sheds light on the difference between memory in other animals and its cultural narrative basis in humans.
The practical obstacles of data transfer: why researchers still love scp

The importance of computing facilities is heralded every six months with the announcement of the new Top500 list, showcasing the world's fastest supercomputers. Unfortunately, with great computing capability does not come great long-term data storage capacity, which often means users must move their data to their local site archive, to remote sites where they may be doing future computation or analysis, or back to their home institution, else face the dreaded data purge that most HPC centers employ to keep utilization of large parallel filesystems low to manage performance and capacity. At HPC centers, data transfer is crucial to the scientific workflow and will increase in importance as computing systems grow in size. The Energy Sciences Network (ESnet) recently launched its fifth generation network, a 100 Gbps high-performance, unclassified national network connecting more than 40 DOE research sites to support scientific research and collaboration. Despite the tenfold increase in bandwidth to DOE research sites amenable to multiple data transfer streams and high throughput, in practice, researchers often under-utilize the network and resort to painfully-slow single stream transfer methods such as scp to avoid the complexity of using multiple stream tools such as GridFTP and bbcp, and contend with frustration from the lack of consistency of available tools between sites. In this study we survey and assess the data transfer methods provided at several DOE supported computing facilities, including both leadership-computing facilities, connected through ESnet. We present observed transfer rates, suggested optimizations, and discuss the obstacles the tools must overcome to receive wide-spread adoption over scp.
Effect of dietary lipid on chlorpromazine depression of 32P labeling of rat brain phospholipids

Abstract The action of chlorpromazine in depressing uptake of 32 P into rat brain phospholipids was lowest in animals fed high levels of corn oil, in comparison with rats fed beef fat, or fish oils. While this response is related to hypothermia produced by chlorpromazine, the differences in body temperature did not appear to be sufficient to account for the differences in this chlorpromazine activity among the animals fed different lipids.
Expression of Interferon-inducible RNA Adenosine Deaminase ADAR1 during Pathogen Infection and Mouse Embryo Development Involves Tissue-selective Promoter Utilization and Alternative Splicing

ADAR1 (adenosine deaminase acting on RNA) is widely expressed in adult mammals and has a critical role during embryogenesis. Two size forms of ADAR1 are known that possess adenosine-to-inosine editing activity: an interferon (IFN)-inducible ∼150-kDa protein and a constitutively expressed N-terminally truncated ∼110-kDa protein. We defined the structure of the 5′-flanking region of the mouse Adar1 gene, and we show here that mouse Adar1 transcripts possess alternative exon 1 structures (1A, 1B, and 1C) that initiate from unique promoters and are spliced to a common exon 2 junction. Exon 1A-containing transcripts encoding p150 were expressed in all tissues examined from adult mice (brain, cecum, heart, kidney, liver, lung, spleen, and Peyer's patches) and were elevated most significantly in liver but remained lowest in brain following oral infection with Salmonella. Exon 1B-containing RNA was most abundant in brain and was not increased in any tissue examined following infection. Exon 1C-containing RNA was very scarce. Exon 1A, but not exon 1B or 1C, expression was increased in fibroblast L cells treated with IFN, and a consensus ISRE element was present in the promoter driving exon 1A expression. Exon 1B, but not 1A, was detectable in embryonic day 10.5 embryos and was abundantly expressed in embryonic day 15 embryos. Furthermore, the ADAR1 p110 protein isoform was detected in embryonic tissue, whereas both p110 and the inducible p150 proteins were found in IFN-treated L cells. Finally, the presence of alternative exon 7a correlated with exon 1B-containing RNA, and alternative exon 7b correlated with exon 1A-containing RNA. These results establish that multiple promoters drive the expression of the Adar1 gene in adult mice, that the IFN inducible promoter and exon 1A-containing RNA are primarily responsible for the increased ADAR1 observed in Salmonella-infected mice, and that the constitutive exon 1B-containing transcript and encoded p110 protein product are abundantly expressed both in adult brain and during embryogenesis.
Symmetric inverse consistent nonlinear registration driven by mutual information

A nonlinear viscoelastic image registration algorithm based on the demons paradigm and incorporating inverse consistent constraint (ICC) is implemented. An inverse consistent and symmetric cost function using mutual information (MI) as a similarity measure is employed. The cost function also includes regularization of transformation and inverse consistent error (ICE). The uncertainties in balancing various terms in the cost function are avoided by alternatively minimizing the similarity measure, the regularization of the transformation, and the ICE terms. The diffeomorphism of registration for preventing folding and/or tearing in the deformation is achieved by the composition scheme. The quality of image registration is first demonstrated by constructing brain atlas from 20 adult brains (age range 30-60). It is shown that with this registration technique: (1) the Jacobian determinant is positive for all voxels and (2) the average ICE is around 0.004 voxels with a maximum value below 0.1 voxels. Further, the deformation-based segmentation on Internet Brain Segmentation Repository, a publicly available dataset, has yielded high Dice similarity index (DSI) of 94.7% for the cerebellum and 74.7% for the hippocampus, attesting to the quality of our registration method.
Diagnostic evaluation of newly arrived asymptomatic refugees with eosinophilia.

BACKGROUND Refugees may arrive for resettlement with asymptomatic parasitic infections, and eosinophilia may be the only clue to the presence of infection. Our aim was to determine the prevalence of eosinophilia and develop a standardized approach to the evaluation of asymptomatic refugees with eosinophilia. METHODS We reviewed the medical records of refugees seen from October 1998 through May 2002 at Boston Medical Center. Data examined included age, country of origin, absolute eosinophil count, results of stool ova and parasite testing, and results of serological testing for Strongyloides stercoralis, Schistosoma species, and filaria. RESULTS Eosinophilia--defined as an absolute eosinophil count of >or=450 cells/microL--was present in 266 (12%) of 2224 refugees. Patients with eosinophilia ranged in age from 2 months to 81 years and had arrived from Africa, Eastern Europe, Southeast Asia, South America, the Caribbean, and the Middle East. Absolute eosinophil counts ranged from 450 to 3224 cells/microL. Pathogens were identified in stool samples of 76 (29%) of 265 patients. Serological testing for S. stercoralis, Schistosoma species, and/or filaria was done for 120 (45%) of 266 patients. Results of serological testing were positive for S. stercoralis in 45 (39%) of 115 patients, for Schistosoma species in 15 (22%) of 67 patients, and for filaria in 18 (51%) of 35 patients. Serological evidence of parasitic infection was seen at all levels of eosinophilia and in patients with and without pathogens identified in their stool samples. CONCLUSIONS Systematic evaluation for parasites in asymptomatic, newly arrived refugees with eosinophilia should include stool ova and parasite examination, serological examination for S. stercoralis for all patients, and serological examination for Schistosoma species and filaria in patients from regions where these organisms are endemic.
Impact of flow on ligand-mediated bacterial flocculation.

To understand the adhesion–fragmentation dynamics of bacterial aggregates (i.e., flocs), we model the aggregates as two ligand-covered rigid spheres. We develop and investigate a model for the attachment/detachment dynamics in a fluid subject to a homogeneous planar shear-flow. The binding ligands on the surface of the flocs experience attractive and repulsive surface forces in an ionic medium and exhibit finite resistance to rotation (via bond tilting). For certain range of material and fluid parameters, our results predict a nonlinear or hysteretic relationship between the binding/unbinding of the floc surface and the net floc velocity (translational plus rotational velocity). We show that the surface adhesion is promoted by increased fluid flow until a critical value, beyond which the bonds starts to yield. Moreover, adhesion is not promoted in a medium with low ionic strength, or flocs with bigger size or higher binder stiffness. The numerical simulations of floc-aggregate number density studies support these findings.
Recognition of flexible objects

Vision systems typically incorporate object rigidity constraints. Such constraints are meaningful in manufacturing processes, but not in the natural visual world, where elastic objects, jointed objects, a variety of viewing geometry deformations, and variations of structure within an object class are common. This work extends the capabilities of recognition algorithms to the realm of flexible objects, discussing the development of algorithms, data structures and mathematical models for the recognition of flexible objects from a single image. >
Multi-link-speed network topology design

The authors consider the problem of selecting a link topology and sizing the link given a point-to-point traffic matrix and a cost matrix. Different speed links are permitted in the topology. An algorithm is presented for the solution to this problem, and its performance, both in terms of running time and the quality of the networks produced, is compared with that of an algorithm which only considers a single speed link. The new algorithm shows significant improvement, reducing cost by as much as 6% while increasing running time by only a constant factor. >
Use of cardiac magnetic resonance imaging in surgical ventricular restoration

Objective: Surgical ventricular restoration (SVR) is a promising modality for treatment of heart failure due to left ventricular systolic dysfunction,particularlythat dueto ischemicheart disease. Therole of MRI inimproving diagnosis, operativeplanning,and follow-up is reviewed to analyze how one examination may define a spectrum of important considerations. Methods: Proper patient selection and optimal surgical planning relies on accurate assessment of measures of ventricular volume, function, and viability, and of the mechanics of the mitral valve apparatus. A complete preoperative imaging evaluation includes assessment of the left ventricular volume (both systolic and diastolic), regional and global systolic function, viability of the target area for surgical exclusion and of the remote myocardium, determination of the adequacy of the remote myocardium remaining after proposed SVR to support circulatory function, and of the mitral annular dilatation and inter papillary muscle spacing, factors which contribute to functional mitral regurgitation. Results: Cardiac magnetic resonance imaging (MRI) allows a complete evaluation of these quantities: the ventricular systolic and diastolic volumes (and hence ejection fraction) are easily assessed reproducibly and accurately; the regional wall motion of the asynergic area and the remote myocardium can be measured by several quantitative means, including with myocardial tagging, and the presence or absence of nonviable, irreversible scar can be detected with gadolinium-based interstitial contrast agents. Furthermore, an accurate measurement of the mitral annular dimensions and the papillary muscle spacing can be easily performed using cardiac MRI, allowing planning of effective therapy for mitral regurgitation. Conclusions: The entire imaging study can be performed in less than 1 h, making cardiac MRI a truly useful and comprehensive tool in planning SVR, and for subsequently evaluating results.
SP-SDP for Fuel Consumption and Tailpipe Emissions Minimization in an EVT Hybrid

Control strategies have been developed for hybrid electric vehicles (HEV) that minimize fuel consumption while satisfying a charge sustaining constraint. Since one of the components of an HEV is typically the ubiquitous internal combustion engine, tailpipe emissions must also be considered. This paper uses shortest-path stochastic dynamic programming (SP-SDP) to address the minimization of a weighted sum of fuel consumption and tailpipe emissions for an HEV equipped with a dual mode electrically variable transmission (EVT) and a catalytic converter. The shortest path formulation of SDP is chosen to directly address the charge sustaining requirement. Using simple methods, an SP-SDP solution required more than eight thousand hours. Using linear programming and duality, an SP-SDP problem is solved in about three hours on a desktop PC. The resulting time-invariant feedback controller reduces tailpipe emissions by more than 50% when compared to a popular baseline controller.
A Defense of Modern Foreign Languages—With Reservations*

(Author's summary.-The outline of a six-year French course is followed by the defense of certain inclusions [emphasis on reading, isolation of grammar] and exclusions [daily translation, use of realia, oral work] and by the defense-with reservations-of the modern foreign languages as a secondary-school subject. A digression gives some of the writer's experiences that indicate the impossibility of learning to speak French in the classroom.)
Synthesis and Optical Properties of Anisotropic Metal Nanoparticles

In this paper we overview our recent studies of anisotropic noble metal (e.g. gold and silver) nanoparticles, in which a combination of theory and experiment has been used to elucidate the extinction spectra of the particles, as well as information related to their surface enhanced Raman spectroscopy. We used wet-chemical methods to generate several structurally well-defined nanostructures other than solid spheres, including silver nanodisks and triangular nanoprisms, and gold nanoshells and multipods. When solid spheres are transformed into one of these shapes, the surface plasmon resonances in these particles are strongly affected, typically red-shifting and even splitting into distinctive dipole and quadrupole plasmon modes. In parallel, we have developed computational electrodynamics methods based on the discrete dipole approximation (DDA) method to determine the origins of these intriguing optical features. This has resulted in considerable insight concerning the variation of plasmon wavelength with nanoparticle size, shape and dielectric environment, as well as the use of these particles for optical sensing applications.
A Virtual Test Facility for the Simulation of Dynamic Response in Materials

The Center for Simulating Dynamic Response of Materials at the California Institute of Technology is constructing a virtual shock physics facility for studying the response of various target materials to very strong shocks. The Virtual Test Facility (VTF) is an end-to-end, fully three-dimensional simulation of the detonation of high explosives (HE), shock wave propagation, solid material response to pressure loading, and compressible turbulence. The VTF largely consists of a parallel fluid solver and a parallel solid mechanics package that are coupled together by the exchange of boundary data. The Eulerian fluid code and Lagrangian solid mechanics model interact via a novel approach based on level sets. The two main computational packages are integrated through the use of Pyre, a problem solving environment written in the Python scripting language. Pyre allows application developers to interchange various computational models and solver packages without recompiling code, and it provides standardized access to several data visualization engines and data input mechanisms. In this paper, we outline the main components of the VTF, discuss their integration via Pyre, and describe some recent accomplishments in large-scale simulation using the VTF.
Local Differential Perturbations: Location Privacy under Approximate Knowledge Attackers

Location privacy research has received wide attention in the past few years owing to the growing popularity of location-based applications, and the skepticism thereof on the collection of location information. A large section of this research is directed toward mechanisms based on location obfuscation enforced using cloaking regions. The primary motivation for this engagement comes from the relatively well-researched area of database privacy. Researchers in this sibling domain have indicated multiple times that any notion of privacy is incomplete without explicit statements on the capabilities of an adversary. As a result, we have started to see some efforts to categorize the various forms of background knowledge that an adversary may possess in the context of location privacy. Along this line, we consider some preliminary forms of attacker knowledge, and explore what implication does a certain form of knowledge has on location privacy. Continuing on, we extend our insights to a form of adversarial knowledge related to the geographic uncertainty that the adversary has in correctly locating a user. We empirically demonstrate that the use of cloaking regions can adversely impact the preservation of privacy in the presence of such approximate location knowledge, and demonstrate how perturbation-based mechanisms can instead provide a well-balanced tradeoff between privacy and service accuracy.
Delayed-Onset Primary Cytomegalovirus Disease and the Risk of Allograft Failure and Mortality after Kidney Transplantation

Background. During the contemporary era of antiviral prophylaxis, the impact of delayed-onset primary cytomegalovirus (CMV) disease on the outcome of kidney transplantation is not known. We evaluated the incidence, clinical features, risk factors, and outcomes of CMV disease among high-risk kidney transplant recipients. Methods. The medical records of CMV-seronegative recipients of kidney transplants from CMV-seropositive donors were reviewed. Cox proportional hazards regression was used to identify factors associated with CMV disease and to assess its impact on allograft loss and mortality. Results. None of the 176 CMV-seronegative recipients of kidney transplants from CMV-seropositive donors developed breakthrough CMV disease during a median of 92 days (interquartile range, 90-92 days) of oral ganciclovir or valganciclovir prophylaxis. Thereafter, 51 patients (29%) developed CMV disease at a median of 61 days (interquartile range, 40-143 days) after stopping antiviral prophylaxis. Early-onset bacterial and fungal infection (hazard ratio, 3.61; 95% confidence interval, 1.78-7.33; P<.001) and a Charlson comorbidity index ≥3 (hazard ratio, 2.21; 95% confidence interval, 1.15-4.22; P =.011) were associated with a higher risk of delayed-onset primary CMV disease, and postrejection antiviral prophylaxis (hazard ratio, 0.29; 95% confidence interval, 0.09-0.94; P =.039) was associated with a lower risk of such CMV disease. A time-dependent Cox regression analysis revealed a statistically significant association between tissue-invasive CMV disease and allograft loss or mortality (hazard ratio, 2.85; 95% confidence interval, 1.22-6.67; P =.016). Conclusion. This study of a large cohort of CMV-seronegative recipients of kidney transplants from CMV-seropositive donors illustrates the ongoing challenge of delayed-onset primary CMV disease and its impact on transplantation outcomes despite antiviral prophylaxis. Better strategies for CMV disease prevention after kidney transplantation are warranted.
Combining textual and structural analysis of software artifacts for traceability link recovery

Existing methods for recovering traceability links among software documentation artifacts analyze textual similarities among these artifacts. It may be the case, however, that related documentation elements share little terminology or phrasing. This paper presents a technique for indirectly recovering these traceability links in requirements documentation by combining textual with structural information as we conjecture that related requirements share related source code elements. A preliminary case study indicates that our combined approach improves the precision and recall of recovering relevant links among documents as compared to stand-alone methods based solely on analyzing textual similarities.
Moral Leadership in Nursing

Abstract In order for the moral activity of nursing to occur, all nurses—from the board room to the patient room—must embrace the ideal of their duties and obligations related to moral leadership in nursing. Understanding the issues that affect the environment of care is a responsibility regardless of the nurses’ role—educators, administrators, clinicians, and scholars must join together to address the myriad opportunities that exist. Moral leaders embrace key concepts that promote ethical environments, creating a nursing milieu that enhances the quality and safety of patient care.
Somebody's children or nobody's children? How the sociological perspective could enliven research on foster care

Social scientists have long been concerned about how the fortunes of parents affect their children, with acute interest in the most marginalized children. Yet little sociological research considers children in foster care. In this review, we take a three-pronged approach to show why this inattention is problematic. First, we provide overviews of the history of the foster care system and how children end up in foster care, as well as an estimate of how many children ever enter foster care. Second, we review research on the factors that shape the risk of foster care placement and foster care caseloads and how foster care affects children. We close by discussing how a sociological perspective and methodological orientation—ranging from ethnographic observation to longitudinal mixed methods research, demographic methods, and experimental studies—can foster new knowledge around the foster care system and the families it affects.
Radiosensitivity in vitro of human fibroblasts derived from patients with a severe skin reaction to radiation therapy

Abstract Skin fibroblasts derived from six cancer patients who showed an unusually severe skin reaction to radiation therapy also showed enhanced radiation sensitivitv in vitro .
Filial caregiving is associated with greater neuroendocrine dysfunction: Evidence from the 2005 National Survey of Midlife in the United States

Objectives:This study examined associations between providing caregiving for a biological or adoptive parent and clinically assessed biological risk factors (allostatic load and its three subscales...
Genome-Wide Microarray Analyses Identify the Protein C Receptor as a Novel Calcineurin/Nuclear Factor of Activated T Cells–Dependent Gene in Vascular Smooth Muscle Cell Phenotypic Modulation

Objective— Calcineurin (Cn) and the nuclear factor of activated T cells (NFAT) family of transcription factors are critical in vascular smooth muscle cell (SMC) development and pathology. Here, we used a genomics approach to identify and validate NFAT gene targets activated during platelet-derived growth factor-BB (PDGF-BB)–induced SMC phenotypic modulation. Methods and Results— Genome-wide expression arrays were used to identify genes both (1) differentially activated in response to PDGF-BB and (2) whose differential expression was reduced by both the Cn inhibitor cyclosporin A and the NFAT inhibitor A-285222. The 20 most pharmacologically sensitive genes were validated by quantitative reverse transcription–polymerase chain reaction analysis of PDGF-BB-stimulated SMCs in the presence of Cn/NFAT inhibitors, including the VIVIT peptide. In all experiments, protein C receptor (PROCR) gene activation was reduced. We showed that PROCR expression was virtually absent in untreated, quiescent SMCs. PDGF-BB stimulation, however, induced significant PROCR promoter activation and downstream protein expression in a Cn/NFAT-dependent manner. Mutation of a species-conserved, NFAT binding motif significantly attenuated PDGF-BB-induced PROCR promoter activity, thereby distinguishing NFAT as the first PROCR transcriptional activator to date. Moreover, SMC PROCR expression was upregulated in the neointima as early as 7 days following acute vascular injury in rat carotid arteries. Conclusion— We hereby report PROCR as a novel, NFAT-dependent gene that may be implicated in vascular restenosis and consequent inward remodeling.
Student Reactions to the Shootings at Virginia Tech and Northern Illinois University: Does Sharing Grief and Support Over the Internet Affect Recovery?:

After the shootings at Virginia Tech and Northern Illinois University, many students gravitated to the Internet for support. Despite the fact that the Internet plays a major role in how people live their lives in contemporary society, little is known about how people use the Internet in times of tragedy and whether this use affects well-being. To address these issues, the current study assessed the types of online activities more than 200 Virginia Tech and Northern Illinois University students participated in 2 weeks after the shootings and again 6 weeks later, as well as their depressive and posttraumatic stress disorder (PTSD) symptoms. Results showed that 2 weeks after the shootings, nearly 75% of students were suffering from significant psychological distress. Additionally, students participated in numerous online activities related to the shootings. Importantly, students perceived their Internet activities as being beneficial, although there was no evidence that Internet use affected their well-being.
A cluster estimation method with extension to fuzzy model identification

We present an efficient method for estimating cluster centers of numerical data. This method can be used to determine the number of clusters and their initial values for initializing iterative optimization-based clustering algorithms such as fuzzy C-means. Here were combine this cluster estimation method with a least squares estimation algorithm to provide a fast and robust method for identifying fuzzy models from input/output data. A benchmark problem involving the prediction of a chaotic time series shows this method compares favourably with other more compositionally intensive methods. >
The time course of attentional allocation while women high and low in body dissatisfaction view self and model physiques

The purpose of this study was to examine trait levels of dissatisfaction with specific bodily regions and attentional characteristics associated with those regions among women high (HBD, n = 15) and low (LBD, n = 14) in body dissatisfaction. Separate laboratory visits were completed, during, which eye movements were recorded as participants viewed slides of self-physiques or model-physiques. Comparisons of search tendencies were made across the entire 5 s of slide presentation, and then within each of the ten 500 ms epochs that comprised the 5 s viewing period. The HBD group made initial fixations to the pelvis region proportionately more than the LBD group, and avoided looking at their own bodies relative to the LBD group. They also viewed the model's legs significantly longer than the LBD group. When considering the time course of attentional allocation, the HBD group preferentially viewed areas typical of dissatisfaction during the latter viewing periods, regardless of whether they were looking at them...
The effects of cyclo‐oxygenase inhibitors on bile‐injured and normal equine colon

A potential adverse effect of cyclo-oxygenase (COX) inhibitors (nonsteroidal anti-inflammatory drugs [NSAIDs]) in horses is colitis. In addition, we have previously shown an important role for COX-produced prostanoids in recovery of ischaemic-injured equine jejunum. It was hypothesised that the nonselective COX inhibitor flunixin would retard repair of bile-injured colon by preventing production of reparative prostaglandins, whereas the selective COX-2 inhibitor, etodolac would not inhibit repair as a result of continued COX-1 activity. Segments of the pelvic flexure were exposed to 1.5 mmol/l deoxycholate for 30 min, after which they were recovered for 4 h in Ussing chambers. Contrary to the proposed hypothesis, recovery of bile-injured colonic mucosa was not affected by flunixin or etodolac, despite significantly depressed prostanoid production. However, treatment of control tissue with flunixin led to increases in mucosal permeability, whereas treatment with etodolac had no significant effect. Therefore, although recovery from bile-induced colonic injury maybe independent of COX-elaborated prostanoids, treatment of control tissues with nonselective COX inhibitors may lead to marked increases in permeability. Alternatively, selective inhibition of COX-2 may reduce the incidence of adverse effects in horses requiring NSAID therapy.
BIOLOGY OF HYLOBIUS PALES (COLEOPTERA: CURCULIONIDAE) IN THE GEORGIA PIEDMONT

Cultural practices, temperature, and precipitation affect the population fluctuations of Hylobius pales (Herbst) in the piedmont of Georgia. Of the environmental factors, temperature appears to have the most decided influence on the seasonal activity of the weevils. Precipitation may cause some variation but has no effect on general population trends. Cultural practices affect the numbers of weevils collected but not the seasonal trends. Although weevils are long lived and oviposition and larval development occur almost continuously, there are two population peaks during the year.
Sporulation of Clostridium perfringens Type A in Vacuum-Sealed Meats

Type A strains of Clostridium perfringens inoculated into vacuum-sealed packages of hamburger, roast beef, ground beef plus cream sauce, and turkey roll produced high levels of spores.
The Search Behavior of Omnivorous Thrips Larvae is Influenced by Spider Mite Cues

The western flower thrips is an omnivorous insect that consumes both leaf tissue and spider mite eggs. For this reason, these thrips are often described as 'opportunistic predators' of spider mites. Several studies have shown that western flower thrips are often found in association with spider mites, and the development time of thrips decreases and their survivorship increases when they consume spider mite eggs. We tested the hypothesis that thrips larvae may respond to chemical cues from spider mites, and that they may modify their prey-searching behavior when these spider mite-induced cues are present. We prepared hexane extracts from: 1) webbing of spider mites isolated from maize leaves, 2) webbing produced by spider mites inside an empty glass tube to exclude any plant-derived cues from the extract, and 3) spider mite cuticle extracts. These three extracts were subsequently applied in droplets to one-half of filter papers, and hexane alone was applied in droplets to the other half. We showed that residence time of thrips larvae was higher on filter paper with spider mite webbing extract, especially when the extract originated from spider mites isolated in glass tubes. In the presence of webbing extracts, we also observed: 1) a decrease in velocity, 2) an increase of angular velocity and 3) an increase in time immobile. Extracts from spider mite cuticle only increased velocity and proportion of time immobile of the thrips larvae. Our results suggest that chemical cues from spider mite webbing induce an
Preface to: Powered by Feel: How Individuals, Teams, and Companies Excel

How do world-class performing individuals, teams, and companies do what they do? Would you like to know how to perform at your best on a regular basis? This book reveals the results of research involving interviews with hundreds of world-class performers in athletics, business, music, medicine and the military. It also includes the lessons learned from global consulting experiences, involving feel, with a wide and diverse group of corporate executives and independent contributors. Learn how to take your performance to the next level and enjoy it more in the process. Beginning with the answer to a simple question, the authors describe the role of FEEL in world-class performance and how you can make it work for you. This book goes well beyond the cliche of “you need to love what you do and have passion for your work.” Interviewees represented in the book include the following: Olympic Gold Medalists; World Champion Archer; Best-Selling Mystery Author; National Champion Swimmers; FBI Criminal Profiler; Space Shuttle Astronaut; NBA, MLB, and collegiate Coaches of the Year; Former All-Pro and Hall of Fame football player; Professional Poker Champion; Heart Surgeon; NCAA All Americans and Players of the Year; CEOs of several major corporations in services, biotech, financial services, consumer marketing and other businesses; Grammy Award Winners, and more.
A More Exact Theory for Twisted Wire Cables

This note presents a more exact expression for the contact angle between two adjacent wires in the cable. This more exact theory indicates an increase in the contact stresses.
Does Georgia Need a Unitary Tax

The author considers whether Georgia should adopt a unitary corporate income tax. He suggests that it would be better if the state curbed on the use of Delaware holding companies. He also thinks that adopting a value added tax would be preferable to adopting the unitary method.
Telehealth Measures Screening for Developmental Language Disorders in Spanish-Speaking Toddlers.

Abstract Background: This is the second of two studies that described the use of telehealth language screening measures for use with young Spanish-speaking children. Introduction: The purpose of this study was to describe the classification accuracy of individual telehealth language screening measures as well as the accuracy of combinations of measures used with Spanish-speaking toddler-age children from rural and underserved areas of the country. Materials and Methods: This study applied an asynchronous hybrid telehealth approach that implemented parent-structured play activities with a standard set of stimuli, and interaction with a My First Words e-book. These interactions were recorded with a mini camcorder. In addition, a traditional pen and paper parent questionnaire measure was collected. Sixty-two mostly Spanish-speaking preschool-age children and their parents participated. Twenty-two children had developmental language disorders (DLDs) and 40 had typical language development. Results: Although s...
Role of the dopamine transporter in the differential cocaine-induced locomotor activation of inbred long-sleep and short-sleep mice.

The locomotor-stimulant effects of cocaine, mediated through inhibition of the dopamine transporter (DAT), can be influenced by environmental factors. Previously, we found that following a short exposure to the testing environment, cocaine induces greater locomotor activation in inbred long-sleep (ILS) mice, compared to inbred short-sleep (ISS) mice. In the present study, all animals received prolonged habituation to the testing chambers prior to cocaine injection, and the results were compared with those from our previous study. When mice were tested with saline on day 1 and with either saline or cocaine (10–20 mg/kg) on day 2, we observed significant locomotor stimulation in ILS, but not ISS, mice at all tested doses of cocaine. Thus, prolonged habituation does not alter the differential responsiveness of these two strains of mice to cocaine. We found no strain differences in striatal cocaine levels. However, [3H]WIN 35,428 binding studies showed a lower number of striatal DATs in ILS, compared to ISS, mice. In vivo analysis of striatal DAT activity revealed not only that ILS mice cleared exogenously applied DA more slowly than ISS mice, but also that cocaine (10 mg/kg) decreased DA clearance selectively in ILS mice. Thus, functional differences in striatal DATs between ILS and ISS mice likely contribute to the differential behavioral activation of cocaine in these two mouse strains.
Academic Ideology and the Study of Adjudication

This paper proposes a theory about the differences in perspective that political scientists bring to bear upon their teaching, research, and writing. It also suggests a method which can be used to study such differences. The particular empirical example discussed relates to only one of the subfields of political science, but this report may encourage parallel investigations into the structure of professional academic values in other component areas of the discipline. Such a result would not merely confirm or refute the applicability of the theory as a generalization about political science; it also would enhance our present meager and unsystematized understanding of the extent to which our professional knowledge is affected by our quasi-professional (personal) biases. The development of such understanding evidently ought to be assigned a high priority in any normative schedule of goals relating to the social ecology of scientific inquiry.The phenomenon of analyst value predisposition is by no means peculiar to social science, and most certainly it is not idiosyncratic among political scientists. Psychologist Silvan S. Tomkins recently has called attention to the universality of the problem of academic ideology in all scientific work:At the growing edge of the frontier of all sciences there necessarily is a maximum of uncertainty, and what is lacking in evidence is filled by passion and faith, and hatred and scorn for the disbelievers. Science will never be free of ideology, though yesterday's ideology is today's fact or fiction.
Geochemistry of the Rare Earth Elements in Natural Terrestrial Waters:A Review of What Is Currently Known

The range of observed chemical compositions of natural terrestrial waters varies greatly especially when compared to the essentially constant global composition of the oceans. The concentrations of the REEs in natural terrestrial waters also exhibit more variation than what was reported in seawater. In terrestrial waters, pH values span the range from acid up to alkaline. In addition, terrestrial waters can range from very dilute waters through to highly concentrated brines. The REE concentrations and their behavior in natural terrestrial waters reflect these compositional ranges. Chemical weathering of rocks represents the source of the REEs to natural terrestrial waters and, consequently, the REE signature of rocks can impart their REE signature to associated waters. In addition, because of the typical low solubilities of the REEs, both surface and solution complexation can be important in fractionating REEs in aqueous solution. Both of these processes are important in all natural terrestrial waters, however, their relative importance varies as a function of the overall solution composition. In alkaline waters, for example, solution complexation of the REEs with carbonate ions appears to control their aqueous distributions whereas in acid waters, the REE signature of the labile fraction of the REEs is readily leached from the rocks. In circumneutral pH waters, both processes appear to be important and their relative significance has not yet been determined.
Redescription and Chaetotaxy of Brachychthonius lydiae Adults and Nymphs (Acarina: Oribatei)

Brachychthonius lydiae (Jacot) is redescribed fro the holotype and from specimens from soil in various forest types in Quebec, Canada, and New York and New Hampshire, U.S.A. Descriptions of the protonymph, deutonymph, and tritonymph are included. The mite is readily distinguishable, in all stages studied, by the pinnate setae on the prodorsum and notogaster. The chaetotaxy of B. lydiae is compared with that of Synchthonius elegans Forsslund, Liochthonius perpusillus (Berlese), L. australis Covarrubias , and Eobrachychthonius spp.
Undifferentiated (anaplastic) carcinoma with osteoclast-like giant cells of the pancreas: a series of 5 cases with clinicopathologic correlation and cytomorphologic characterization.

Introduction Undifferentiated carcinoma with osteoclast-like giant cells of the pancreas (UCOGCP) is a rare neoplasm involving the pancreas. Although typically diagnosed initially via endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA), cytomorphologic characterization of the neoplasm has been limited to individual cases in the literature. Materials and methods Five cases were identified in a retrospective review of our institution’s records from 2006 to 2015. Cytomorphologic, immunophenotypic, and corresponding clinical features of the neoplasm are examined and described. Results UCOGCP accounted for 0.9% of all new pancreatic neoplastic diagnoses, had a median greatest dimension of 4.3 cm, were variably located within the pancreas, and had variable features by radiologic imaging. Patients were of a median age of 78 years old at diagnosis, and had a median length of survival of 10 months. Smear-based cytomorphology and histomorphology from cell block preparations show atypical/pleomorphic mononuclear carcinomatous and bland osteoclast-like giant cellular populations. The immunophenotype of the mononuclear carcinomatous component was CD68, CD99, CK7 (variably), CKAE1/AE3 (variably), and, rarely, p40-positive. The osteoclast-like giant cells positively expressed CD68 and CD99. Conclusions Initial diagnosis of UCOGCP is frequently made via EUS-FNA of pancreas tumors, with cytomorphologic features on smears and hematoxylin and eosin stained slides prepared from cell block material being characteristic for the diagnosis. Although the cellular constituents have a consistent immunophenotype, the diagnosis can be based on the morphologic features alone. UCOGCP is an important diagnosis as it may have a distinct clinical course from undifferentiated carcinomas of the pancreas lacking osteoclast-like giant cells.
Research of Location Algorithm on TDOA With Four Satellites

Location on TDOA with multi-satellites is a good passive location architecture. It has the advantage of providing high accuracy and less equipment. An analysis for location algorithm on TDOA with four satellites is presented in this paper. In the end ,simulation result indicates the accracy of different constellation of satellites.
Spasticity: Its Physiology and Management: Part I. Neurophysiology of Spasticity: Classical Concepts

Spasticity, seen so frequently in clinical situations, presents motor signs resembling those produced experimentally by transecting the brain stem of a cat at the intercollicular level. This paper reviews experimental results which elucidate the roles of different brain regions in the genesis of classical decerebrate rigidity and demonstrate the function of the gamma motor system in the maintenance of the rigidity. Interruption of the gamma-spindle loop of a muscle (i.e. interrupting the monosynaptic reflex arc subserving the stretch reflexes) abolishes rigidity in that muscle. This reflex-mediated gamma support of decrebrate rigidity is also a prominent feature of clinical spasticity, making classical decerebrate rigidity a useful model for studying the neural mechanisms underlying spasticity. Not all rididities, however, are gamma dependent. Those rigidities surviving dorsal root rhizotomy are called alpha rigidity. Alpha rigidity results when a brain lesion disrupts descending systems which normally exert a net inhibitory effect upon alpha motoneurons.
Bilateral Spontaneous Steinstrasse and Nephrocalcinosi Associated With Distal Renal Tubular Acidosis

AbstractBilateral spontaneous steinstrasse from the ureteropelvic junction to the distal ureter complicating distal renal tubular acidosis has not been described. We report a case and discuss the clinical presentation, radiographic and metabolic findings, and treatment. Relief of obstructive uropathy with extracorporeal shock wave lithotripsy led to the resolution of the heavy steinstrasse burden.
A muscarinic receptor subtype modulates vagally stimulated bronchial contraction

An in vitro preparation was developed to study vagus nerve-stimulated (preganglionic) and field-stimulated (post-ganglionic) contraction of the rabbit main stem bronchus and to compare the inhibitory effects of muscarinic antagonists on that contraction. The maximal contractile responses (20 V, 0.5 ms, 64 Hz) for either field or vagal stimulation were completely abolished by atropine (60 nM). Hexamethonium (0.1 mM) abolished the response to vagal stimulation but did not affect the field-stimulated response. To compare the effectiveness of atropine and pirenzepine as antagonists at the nerve-smooth muscle junction, inhibition studies of field-stimulated contractions were performed. Pirenzepine was 102- to 178-fold less potent than atropine when compared at the inhibitory concentration of antagonist that produced 25, 50, and 75% inhibition (IC25, IC50, and IC75, respectively), indicating that the muscarinic receptor at the nerve-smooth muscle junction is a muscarinic receptor with low affinity for pirenzepine (M2 subtype). Atropine had similar inhibitory effects on vagal- and field-stimulated contractions. In contrast, pirenzepine was more potent in inhibiting vagally stimulated contraction than field-stimulated contraction, especially at the IC25 where pirenzepine was only 8- to 22-fold less potent than atropine in inhibiting vagally stimulated contraction. These data suggest that an M1 subtype of muscarinic receptor modulates excitatory neurotransmission through bronchial parasympathetic ganglia.
Enhanced Ionic Conductivity of a 1,2,3-Triazolium-Based Poly(siloxane ionic liquid) Homopolymer

A 1,2,3-triazolium-based poly(siloxane ionic liquid) (PSIL) is synthesized by UV-triggered thiol–ene ligation between a poly[(mercaptopropyl)methylsiloxane] and a tailor-made vinyl-functionalized triethylene glycol-based 1,2,3-triazolium ionic liquid. The quantitative nature of the thiol–ene coupling is demonstrated by 1H and 13C NMR, whereas properties of this new PSIL are discussed based on solubility, size exclusion chromatography, differential scanning calorimetry, thermogravimetric analysis, and broadband dielectric spectroscopy measurements. Besides exhibiting low glass transition temperature (Tg = −62 °C) and high thermal stability (Td10 = 284 °C), this new class of poly(1,2,3-triazolium) demonstrates the highest value of bulk anhydrous ionic conductivity reported to date for PILs (σDC = 7 × 10–5 S cm–1 at 30 °C).