cssi/SciSciGPT-SciSciNet huggingface dataset:
Nonlinear stress relaxation in palladium(II) complexes with triblock copolymers of styrene and butadiene

Above 200% strain, the mechanical response of triblock copolymers which contain styrene and butadiene is modified significantly by complexation with dichlorobis(acetonitrile)palladium(II). This pseudosquare-planar transition metal salt forms π-complexes with, and catalyzes the dimerization of, alkene groups in the main chain and the side group of Kraton's butadiene midblock. Between 10 and 100% strain, the plastic flow regime is similar for undiluted Kraton™ and its Pd2+ complexes, but the level of engineering stress is approximately twofold larger for the complex that contains 4 mol % palladium(II) [Pd(II)]. Nonlinear stress relaxation measurements in the plastic flow regime (i.e., beyond the yield point but before the large upturn in stress) are analyzed at several different levels of strain. Transient relaxation moduli were modeled by a three-parameter biexponential decay with two viscoelastic time constants. The longer relaxation time for Kraton™ increases at higher strain, and in the presence of 4 mol % palladium chloride. A phenomenological model is proposed to describe the effect of strain on relaxation times. This model is consistent with the fact that greater length scales are required for cooperative segmental reorganization at larger strain. The resistance Ω to conformational reorganization during stress relaxation is estimated via integration of the normalized relaxation modulus versus time data. This resistance increases at higher initial jump strain because conformational rearrangements are influenced strongly by knots and entanglements at larger strain. The effect of strain on Ω is analyzed in terms of time-strain separability of the relaxation modulus. Linear behavior is observed for Ω versus inverse strain (i.e., 1/e), and the magnitude of the slope [i.e., −dΩ/d(1/e)] is threefold larger in the absence of PdCl2(CH3CN)2. © 2004 Wiley Periodicals, Inc. J Appl Polym Sci 93: 1329–1336, 2004
Charge and spin transport through a metallic ferromagnetic-paramagnetic-ferromagnetic junction

Using a pair of weakly coupled drift-diffusion equations for spin-up and spin-down electrons, we compute the signal of recent spin-injection experiments by Johnson on ferromagnetic-paramagnetic-ferromagnetic films. In the limit of large junction resistance, our results coincide with those of earlier calculations. As the junction resistance decreases, there are correction terms which provide a cutoff to the size of the signal for films much thinner than the spin-diffusion length. The physical origin of this cutoff is the leakage of nonequilibrium magnetization out of the paramagnet into the current and voltage probes. Although our calculation can explain the sample thickness dependence of the experiments, it cannot account for the large magnitude of the signal observed.
Mechanisms for reduction of impulse strength resulting from small water trees

The impulse strength of TR-XLPE cable has been reported to drop to a greater degree than the AC strength as a function of time during service aging. In this contribution, we discuss the mechanisms by which the impulse strength can degrade to a much greater degree than the AC strength. Three frequency dependent mechanisms have been identified which include electro-thermal, electro-mechanical, and electrical.
Do Trehalose and Trehalase Function in Renal Glucose Transport

Maximum catalytic capacity for renal trehalase varied from 20 micromoles (of glucose produced per minute per gram of fresh tissue) for the armadillo down to zero for the rat, the cat, most turtles, fishes, and all birds and snakes investigated. Labeled trehalose could not be demonstrated in the kidney of the rabbit and the rat after injection with labeled glucose. These data do not support the hypothesis that trehalase and trehalose function in the transport of glucose through the kidney.
Generating Resources and Energizing Frameworks Through Inclusive Public Management

ABSTRACT Resources are generally considered important for the practice of management. Potential resources, however, have to be put into use in order to fulfill their potential. In this paper, we use ethnographic research on the city budgeting cycle in Grand Rapids, Michigan, to explore the process of putting potential resources into use to energize desired frameworks as part of the practice of inclusive management.
Generalized fiducial inference

Generalized Fiducial Inference provides a recipe for constructing confidence intervals as well as tools for establishing the asymptotically correct coverage of many of these intervals. Confidence intervals based on the generalized fiducial framework have been applied to a wide range of problems, many of which lack exact pivots, and these intervals have exhibited excellent asymptotic and small sample performance. Generalized fiducial inference has also been used for model selection and simultaneous inference. In this article, the generalized fiducial framework is presented along with important results and applications. In the process, simple examples are used to illustrate the intuition behind and the application of the framework and its tools. WIREs Comput Stat 2014, 6:132–143. doi: 10.1002/wics.1291 For further resources related to this article, please visit the WIREs website. Conflict of interest: The authors have declared no conflicts of interest for this article.
Orthogonal array design for minimizing loss of vitamin B9 in bread

Purpose – The purpose of this paper is to study and minimize loss of vitamin B9 in bread during warming protocol.Design/methodology/approach – In this study, warming intensity, warming time, warming device, and bread storage method were selected as the most effective factors on B9 loss in bread. The variation of B9 in bread and its loss were studied with orthogonal array design (OAD) using the L9 optimization matrix.Findings – With a calculated per cent of contribution (P%) of error of 0.38 per cent and according to the analysis of variance, ANOVA, of the fluorescence data, 86 per cent of B9 was saved by using toaster as the warming device, a bread warming temperature of <200○F and a warming time of <10min. Fluorescence method evaluated warming intensity and warming device as the most powerful factors affecting the B9 concentration in bread with corresponding P% of 42.28 per cent and 41.72 per cent, respectively.Practical implications – In conclusion, heat destroyed significant portion of B9 in bread duri...
Tool wear condition monitoring in drilling operations using hidden Markov models (HMMs)

Monitoring of tool wear condition for drilling is a very important economical consideration in automated manufacturing. Two techniques are proposed in this paper for the on-line identification of tool wear based on the measurement of cutting forces and power signals. These techniques use hidden Markov models (HMMs), commonly used in speech recognition. In the first method, bargraph monitoring of the HMM probabilities is used to track the progress of tool wear during the drilling operation. In the second method, sensor signals that correspond to various types of wear status, e.g., sharp, workable and dull, are classified using a multiple modeling method. Experimental results demonstrate the effectiveness of the proposed methods. Although this work focuses on on-line tool wear condition monitoring for drilling operations, the HMM monitoring techniques introduced in this paper can be applied to other cutting processes.
The relation between velocity dispersion and central galaxy density in clusters of galaxies.

A correlation between cluster velocity dispersion and average central galaxy density is reported. The correlation covers the range from rich clusters to small groups of galaxies, or, in terms of velocity dispersion, from v sub r approximately 1500 to approximately 100 km/s. This result is useful for estimating unknown velocity dispersions in clusters with the aid of the relatively easily determined 0.5 Mpc central galaxy density parameter. When combined with the virial theorem, the above relation also suggests that the mass-to-light ratio of galaxy systems increases with the system's velocity dispersion.
Lymphadenopathy and Jaundice.

A Hispanic man in his 20swith no knownmedical history presented with worsening abdominal pain over 5 days, persistent pruritus, and scleral icterus. The patient noted swelling on the right side of the neck and a 5-kgweight loss over thepast 2months.He reported a history of moderate alcohol consumption, drinking 1 beer per day during the week and approximately 5 to 8 beers over the weekend, but denied any use of nutritional supplements or illicit drugs. Therewasno recent travel outside thestate.Human immunodeficiency virus test results on admission were negative. Physical examination revealed scleral icterus, jaundice, and a fixed right supraclavicular lymphnode conglomerate measuring 6 × 3 cm. Therewas no cervical, left supraclavicular, axillary, or inguinal lymphadenopathy. Computed tomography of the neck, chest, abdomen, and pelvis demonstrated a large right supraclavicular lymph node, extensivemediastinal lymphadenopathy, a large extracardiac mass abutting the left atrium, hepatomegaly, and multiple splenic lesions. Laboratory evaluation demonstrated a total serumbilirubin level of 10.5mg/dLwith a direct component of 8.4 mg/dL (to convert to micromoles per liter, multiply by 17.104). Renal function was normal. Mild leukopenia and slight thrombocytopenia in the absence of associatedanemiawasnotedon initial completebloodcell count. A liver biopsywasperformed, with results shown in Figure 1. Quiz at jamaoncology.com WHAT IS YOURDIAGNOSIS?
A comprehensive trainable error model for sung music queries

We propose a model for errors in sung queries, a variant of the hidden Markov model (HMM). This is a solution to the problem of identifying the degree of similarity between a (typically error-laden) sung query and a potential target in a database of musical works, an important problem in the field of music information retrieval. Similarity metrics are a critical component of "query-by-humming" (QBH) applications which search audio and multimedia databases for strong matches to oral queries. Our model comprehensively expresses the types of error or variation between target and query: cumulative and noncumulative local errors, transposition, tempo and tempo changes, insertions, deletions and modulation. The model is not only expressive, but automatically trainable, or able to learn and generalize from query examples. We present results of simulations, designed to assess the discriminatory potential of the model, and tests with real sung queries, to demonstrate relevance to real-world applications.
System identification of instrumented bridge systems

Several recorded motions for seven bridge systems in California during recent earthquakes were analysed using parametric and non-parametric system identification (SI) methods. The bridges were selected considering the availability of an adequate array of accelerometers and accounting for different structural systems, materials, geometry and soil types. The results of the application of SI methods included identification of modal frequencies and damping ratios. Excellent fits of the recorded motion in the time domain were obtained using parametric methods. The multi-input/single-output SI method was a suitable approach considering the instrumentation layout for these bridges. Use of the constructed linear filters for prediction purposes was also demonstrated for three bridge systems. Reasonable prediction results were obtained considering the various limitations of the procedure. Finally, the study was concluded by identifying the change of the modal frequencies and damping of a particular bridge system in time using recursive filters. Copyright © 2003 John Wiley & Sons, Ltd.
Business models for Internet-based e-procurement systems and B2B electronic markets: an exploratory assessment

Information technology (IT) has long been applied to support the exchange of goods, services and information between organizations. It is with the advent of Internet-based e-procurement systems and business-to-business (B2B) electronic markets that the real opportunities for online transactions have opened up across space and over time. The authors draw on IS and economics theory to investigate the motivation for the various online business models, and the adoption requirements of purchasing firms, through the examination of a set of mini-cases. Our exploratory study finds that private aggregating and negotiating mechanisms are being adopted for large quantity business supply purchases, while public market mechanisms are more often adopted when firms face uncertain and high variance demand. Moreover, market facilitation, expertise sharing and collaboration are gradually attracting more attention, and call for future investigation.
Sidney and RDS: an evaluation of two persistent storage systems

Comparative experimentation is increasingly important in computer science, but performing such experiments can be challenging. The paper presents a set of experiments that compare the performance of two persistent storage managers, and answer the question of whether the safer storage manager has performance comparable to the less safe one. This comparison was difficult for a number of reasons, among them: relatively few programs using either storage manager existed and no established benchmarks existed, and the two techniques are incompatible at the source code level, thus making a direct comparison impossible. In particular one storage manager used a malloc-and-free style of dynamic storage allocation, while the other used a high performance concurrent garbage collector. A number of approaches were used to overcome this difficulty. The most novel approach involved tracing the memory management of a production program that used the malloc-and-free based storage manager and then replaying the trace in an environment that allowed garbage collection and malloc-and-free to be compared. The study represents the most extensive study of a garbage collected persistent storage system to date.
Hearing Stories That Violate Expectations Leads to Emotional Broadcasting

Emotional Broadcaster Theory (EBT) proposes that the need to disclose turns people into news broadcasters whose stories inform others of major events. The present research tested whether the discrepancy theory of emotion explains emotional broadcasting. Study 1 showed that hearers anticipated being more strongly affected by and more likely to retell unusual stories (per discrepancy theory) than stories conveyed by a distressed teller (per emotional contagion theory). Study 2 tested whether the same unusual event (violence) would be disclosed more by people for whom violence is unexpected. As predicted, people with minimal exposure to violence regarded violence as more disturbing and as more likely to be disclosed than did those with extensive exposure to violence. Study 3 replicated Study 2, and showed that violence exposure moderated anticipated emotional arousal and disclosure only for violent events but not for unusual nonviolent events. Neither violence seeking nor social desirability confounded these results.
Strategies in Motor Stroke Rehabilitation

To the Editor: We read with interest the report by Woldag et al about increased corticomotoneuronal excitability targeting muscles in the paretic hand of chronic stroke patients during voluntary contraction of the healthy hand.1 The authors interpreted their results as supportive of the concept that use of the unaffected hand may exert a beneficial effect on paretic hand function. We raise your attention to 2 issues that impact on this interpretation. First, measurements of corticomotoneuronal excitability provide mechanistic information on brain activity but do not represent a surrogate marker of paretic hand function. This report carefully describes changes in excitability. In the absence of measures of motor function, it is difficult to assess the functional relevance of these results on neurorehabilitation. For example, …
Effect of chronic caloric restriction on the circadian regulation of physiological and behavioral variables in old male B6C3F1 mice.

The circadian rhythms of food and water consumption, the number of feeding and drinking episodes, oxygen consumption, carbon dioxide production, respiratory quotient, gross motor activity, and body temperature were measured in male B6C3F, mice that were fed ad libitum (AL) or fed a caloric-restricted diet (CR). The CR regimen (60% of the normal AL consumption) was fed to mice during the daytime (5 hr after lights on). CR animals exhibited fewer feeding episodes but consumed more food per feeding bout and spent more total time feeding than AL mice. It appears that CR caused mice to change from their normal “nibbling behavior” to meal feeding. Compared to AL animals, the mean body temperature was reduced in CR animals, while the amplitude of the body temperature rhythm was increased. Spans of reduced activity, metabolism, and body temperature (torpor) occurred in CR mice for several hours immediately before feeding, during times of high fatty acid metabolism (low RQ). The acute availability of exogenous sub...
Grade Validity of Online Quantitative Courses.

Are prospective employers getting “quality” educated degreed applicants and are academic institutions that offer online degree programs ensuring the quality control of the courses/programs offered? The issue specifically addressed in this paper is not with all institutions offering degrees through online programs or even with all online courses. The concern is with those online courses where the means to ensure the validity of course grades is not guaranteed by measures of technology or academic rigor employed. More specifically, the practical measures to reduce or eliminate doubts about a student’s acquired knowledge in quantitative online courses need evaluation and thought to arrive at a more circumspect solution. Is the grade earned truly indicative of a student’s competency and level of acquired knowledge and understanding in an online quantitative course or merely an indication that the student somehow just satisfied proscribed evaluative criteria set by the faculty member without adequate measures of assessment?
A human factors design investigation of a computerized layout system of text-graphic technical materials

In converting task listings into multiple pages of documentation for job aids or training, the two major problems are deciding how much material should go on each page and how text and graphics should be laid out on the page. A questionnaire study was used to collect input from 14 human factors personnel in order to design algorithms for page splitting and page layout. From the rules or heuristics used for page splitting, an algorithm was devised that closely matched human page-splitting results. Layout of individual pages was automated with an algorithm based on the (significant) consensus among the subjects on questions of graphics positioning and label ordering. The two algorithms have been combined in a computer-aided design procedure that automatically pages task lists and lays out individual pages.
heroic: 3D general relativistic radiative post-processor with comptonization for black hole accretion discs

We describe HEROIC, an upgraded version of the relativistic radiative postprocessor code HERO described in a previous paper, but which now Includes Comptonization. HEROIC models Comptonization via the Kompaneets equation, using a quadratic approximation for the source function in the short characteristics radiation solver. It employs a simple form of accelerated lambda iteration to handle regions of high scattering opacity. In addition to solving for the radiation eld, HEROIC also solves for the gas temperature by applying the condition of radiative equilibrium. We present benchmarks and tests of the Comptonization module in HEROIC with simple 1D and 3D scattering problems. We also test the ability of the code to handle various relativistic eects using model atmospheres and accretion
Water quality change in the Mississippi River, including a warming river, explains decades of wetland plant biomass change within its Balize delta

Abstract Ecosystem properties of riverine wetlands are known for high inter-annual variability. This multi-decadal study within the wetland complex of the Mississippi River’s Balize Delta, USA assesses how river parameters (temperature, discharge, and sediment load) impact wetland plant biomass over time and space. The Mississippi River’s annual temperature has increased 0.9 °C/decade, while discharge and sediment load has varied without trend over the same period. End-of-season herbaceous biomass increased 14 g/m 2 /year between 1988 and 2008, extrapolating to large (m-ton) area-wide increases. The river’s temperature, discharge and sediment impacted the Delta’s biomass in two ways: the increase in temperature had a positive impact on the growing season length which increased biomass; whereas discharge and load had negative impacts affecting the inter-annual variation without a temporal trend. The results explain natural variability in ecosystem processes in a dynamic deltaic system and likely trace a signal related to both climate warming and land use change within the drainage of the Mississippi River. The discovered decadal increase in herbaceous biomass has implications on carbon storage in the inshore and offshore receiving basins of the world’s riverine wetlands experiencing longer growing seasons.
The Hydnaceae of Iowa. I. The Genera Grandinia and Oxydontia

The fungi here described were all collected in Iowa with the single exception of Grandinia granulosa Fries. These have more than local interest since the occurrence of several species has ap? parently not previously been reported from the United States. The published records of resupinate species of the Hydnaceae in this country, however, are not believed to be a fair index of their frequency or distribution. Many of the little known species are common in Iowa. The vast collections of undetermined material
Sclerosing carcinoma of the hepatic bile ducts.

Although sclerosing carcinoma of the bile ducts has frequently been a well differentiated tumor which has remained localized without evidence of metastasis for long periods of time, the delays in diagnosis, the problems in surgical approach and removal of the tumors, and the associated complications have continued to give this lesion a grave prognosis.
Conclusion: The Politics of Emotions, Campaigns, and Looking Ahead

The concluding chapter examines and reviews the importance of studying emotions in political contexts and the important contributions made by the research on emotions across three presidential election cycles. The research suggests there are discernible contexts in which negative emotions are associated with retrospective voting appraisals and, by the same measure, specific political environments in which positive emotions are associated with prospective voting appraisals. On the eve of the 2016 presidential election, this chapter looks ahead and provides a brief survey of the elements that will shape the political context and campaign narratives framing the choices for voters.
Motivation in caring labor: Implications for the well-being and employment outcomes of nurses

For nurses and other caregivers there is a strong emphasis on prosocial forms of motivation, or doing the job because you want to help others, even in formal, institutionalized care settings. This emphasis is based in gendered assumptions that altruistic motivations are the "right" reasons for being a nurse and lead to the best outcomes for workers and patients. Other motivations for pursuing care work, particularly extrinsic motivation, depart from the prosocial model of care and may be indicative of substandard outcomes, but little research has examined variation in care workers' motivations for doing their jobs. In this study, we use survey data collected from 730 acute care hospital nurses working within one health care system in the Midwestern United States to examine whether different sources of motivation for being a nurse are related to nurse job burnout, negative physical symptoms, and turnover intentions. Our findings suggest that nurses who have high intrinsic and extrinsic motivation actually have better perceived health and employment outcomes (i.e., less likely to say that they will leave, lower burnout, fewer negative physical symptoms) than those with high prosocial motivation, who are more likely to report job burnout.
Unphysical divergences in response theory

Transition densities between excited states are key for nonlinear theoretical spectroscopy and multi-state non-adiabatic molecular dynamics (NAMD) simulations. In the framework of response theory, these transition densities are accessible from poles of the quadratic response function. It was shown recently that the thus obtained transition densities within time-dependent Hartree-Fock (TDHF) and adiabatic time-dependent density functional theory (TDDFT) exhibit unphysical divergences when the difference in excitation energy of the two states of interest matches another excitation energy. This unphysical behavior is a consequence of spurious poles in the quadratic response function. We show that the incorrect pole structure of the quadratic response is not limited to TDHF and adiabatic TDDFT, but is also present in many other approximate many-electron response functions, including those from coupled cluster and multiconfigurational self-consistent field response theory. The divergences appear in regions of the potential energy surface where the ground state is perfectly well behaved, and they are frequently encountered in NAMD simulations of photochemical reactions. The origin of the divergences is traced to an incorrect instantaneous time-dependence of the effective Hamiltonian. The implications for computations of frequency-dependent response properties are considerable and call into question the validity of conventional approximate many-electron response theories beyond linear response.
Relation of Left Atrial Size to Atrial Fibrillation in Patients Aged ≤22 Years.

Left atrial (LA) dilation has been shown to be associated with atrial fibrillation (AF) in the adult population, with some studies indicating that larger LAs are more prone to AF recurrence. The relation of LA size to AF in the pediatric and young adult population has not been investigated. In this study, all pediatric patients (aged ≤22 years) who presented to Boston Children's Hospital from January 2002 to December 2012 with AF were reviewed. Patients with significant congenital heart disease, cardiomyopathies, proven channelopathies, previous cardiac surgery, end-stage renal disease, or severe lung disease/cystic fibrosis were excluded. LA measurements were taken using the echocardiogram performed at the initial presentation. In total, 48 patients with AF were identified. The median age at presentation was 17.1 years (range 3.7 to 22.9 years); 38 patients (79%) were men. Eleven patients (23%) had at least 1 recurrence of their AF. There was no difference in body mass index, prevalence of systemic hypertension, alcohol, stimulant, or illicit drug use between those who had an isolated episode of AF and those who had a recurrence. There was no significant difference in LA dimension Z -scores between groups, with only 2 patients (1 isolated AF, 1 recurrent AF) having Z -scores >2. In conclusion, AF in the young without underlying heart disease is not associated with LA dilation.
Dermal and Subcutaneous Chronic Graft-Versus-Host Disease

Dermal and subcutaneous chronic graft-versus-host disease (cGVHD) is a severely restricting form of cGVHD, which may begin insidiously before progressing to ulcerations, limb movement limitations, and even restrictive lung disease. Multiple studies have demonstrated the use of total body irradiation and mobilized stem cells as risks for this form of cGVHD. As more peripheral blood-based hematopoietic stem cell transplants (HSCT) are performed, the incidence of this form of cGVHD is likely to increase. Several unique clinical signs can help to identify early disease.
Influences on patient satisfaction in healthcare centers: a semi-quantitative study over 5 years.

Knowledge of ambulatory patients’ satisfaction with clinic visits help improve communication and delivery of healthcare. The goal was to examine patient satisfaction in a primary care setting, identify how selected patient and physician setting and characteristics affected satisfaction, and determine if feedback provided to medical directors over time impacted patient satisfaction. A three-phase, semi-quantitative analysis was performed using anonymous, validated patient satisfaction surveys collected from 889 ambulatory outpatients in 6 healthcare centers over 5-years. Patients’ responses to 21 questions were analyzed by principal components varimax rotated factor analysis. Three classifiable components emerged: Satisfaction with Physician, Availability/Convenience, and Orderly/Time. To study the effects of several independent variables (location of clinics, patients’ and physicians’ age, education level and duration at the clinic), data were subjected to multivariate analysis of variance (MANOVA).. Changes in the healthcare centers over time were not significantly related to patient satisfaction. However, location of the center did affect satisfaction. Urban patients were more satisfied with their physicians than rural, and inner city patients were less satisfied than urban or rural on Availability/Convenience and less satisfied than urban patients on Orderly/Time. How long a patient attended a center most affected satisfaction, with patients attending >10 years more satisfied in all three components than those attending 60 years old. Patients were significantly more satisfied with their 30–40 year-old physicians compared with those over 60. On Orderly/Time, patients were more satisfied with physicians who were in their 50′s than physicians >60. Improvement in patient satisfaction includes a need for immediate, specific feedback. Although Medical Directors received feedback yearly, we found no significant changes in patient satisfaction over time. Our results suggest that, to increase satisfaction, patients with lower education, those who are sicker, and those who are new to the center likely would benefit from additional high quality interactions with their physicians.
Unit-bar migration and bar-trough deposition: impacts on hydraulic conductivity and grain size heterogeneity in a sandy streambed

The hydrologic function of riverbeds is greatly dependent upon the spatiotemporal distribution of hydraulic conductivity and grain size. Vertical hydraulic conductivity (K v) is highly variable in space and time, and controls the rate of stream–aquifer interaction. Links between sedimentary processes, deposits, and K v heterogeneity have not been well established from field studies. Unit bars are building blocks of fluvial deposits and are key to understanding controls on heterogeneity. This study links unit bar migration to K v and grain size variability in a sand-dominated, low-sinuosity stream in Nebraska (USA) during a single 10-day hydrologic event. An incipient bar formed parallel to the thalweg and was highly permeable and homogenous. During high flow, this bar was submerged under 10–20 cm of water and migrated ~ 100 m downstream and toward the channel margin, where it became markedly heterogeneous. Low-K v zones formed in the subsequent heterogeneous bar downstream of the original 15–40-cm-thick bar front and past abandoned bridge pilings. These low-K v zones correspond to a discontinuous 1-cm layer of fine sand and silt deposited in the bar trough. Findings show that K v heterogeneity relates chiefly to the deposition of suspended materials in low-velocity zones downstream of the bar and obstructions, and to their subsequent burial by migration of the bar during high flow. Deposition of the unit bar itself, although it emplaced the vast majority of the sediment volume, was secondary to bar-trough deposition as a control on the overall pattern of heterogeneity.
Replacing Recycling Rates with Life-Cycle Metrics as Government Materials Management Targets

In Florida, the passing of the Energy, Climate Change, and Economic Security Act of 2008 established a statewide mass-based municipal solid waste recycling rate goal of 75% by 2020. In this study, we describe an alternative approach to tracking performance of materials management systems that incorporates life-cycle thinking. Using both greenhouse gas (GHG) emissions and energy use as life-cycle indicators, we create two different materials management baselines based on a hypothetical 75% recycling rate in Florida in 2008. GHG emission and energy use footprints resulting from various 2020 materials management strategies are compared to these baselines, with the results normalized to the same mass-based 75% recycling rate. For most scenarios, LCI-normalized recycling rates are greater than mass-based recycling rates. Materials management strategies that include recycling of curbside-collected materials such as metal, paper, and plastic result in the largest GHG- and energy-normalized recycling rates. Waste...
Writing-Intensive Courses

Writing about the performing arts generally refers not only to other written artifacts but also to bodies in motion, images, and sounds. The case studies in this chapter present writing assignments that deal directly with the problem of representing the non-verbal in writing and with the challenge of writing for a non-academic audience. K. Dawn Grapes’ case study outlines a sequence of program notes writing assignments requiring incorporated research, critical thinking, and adherence to style guidelines, with the goal of successfully preparing students for longer, more in-depth writing projects. James Brock details his discovery that the introduction of practices from theatre could help creative writing students to discover that they are polyvocal performers, and that they have many voices.
Association of MRI Measurements with Cognitive Outcomes After STN‐DBS in Parkinson's Disease

Objectives Subthalamic nucleus deep brain stimulation (STN-DBS) is an effective treatment for improving the motor symptoms of Parkinson's disease (PD). Overall, cognitive function remains stable after STN-DBS in most patients. However, cognitive decline, specifically in the verbal fluency domain, is seen in a subset of STN-DBS patients. Currently, predictors of cognitive decline in PD patients treated with STN-DBS are not well known. Thus, identification of presurgical predictors might provide an important clinical tool for better risk-to-benefit assessment. This study explores whether whole brain white matter lesion (WML) volume, or hippocampal and forebrain volumes, measured quantitatively on MRI, are associated with cognitive changes following STN-DBS in PD patients. Methods We conducted a retrospective study using presurgical, and ≥ 6-month postsurgical neuropsychological (NP) evaluation scores from 43 PD patients with STN-DBS. Mean pre/post NP test scores for measures of executive function, attention, verbal fluency, memory, and visuospatial function were analyzed and correlated with WML volume, and brain volumetric data. Results Although cognitive measures of verbal fluency, executive function, attention, memory, and visuospatial function showed declines following STN-DBS, we observed limited evidence that white matter lesion burden or cortical atrophy contributed to cognitive change following STN-DBS. Conclusions These results suggest that post-STN-DBS cognitive changes may be unrelated to presurgical WML burden and presence of cortical atrophy.
Colorectal cancer gene expression profiling using nanostring nCounter analysis.

3555 Background: A more accurate method of identifying stage 2 and 3 colorectal cancer (CRC) patients at highest risk for recurrence after surgical resection is needed. Gene expression signatures utilizing microarray-derived gene expression data from fresh frozen primary CRCs to predict risk of recurrence have been developed by us and others. Advances in technology platforms for gene expression measurements and their applicability to formalin-fixed, paraffin-embedded (FFPE) specimens offer new opportunity to develop clinically useful diagnostics based on molecular profiles. Methods: 58 patient FFPE samples of all stages stored from 1-12 years were collected from the Vanderbilt GI SPORE Translational Pathology and Imaging Core and annotated with appropriate clinicopathologic data. 414 genes were selected from our 34-gene prognostic classifier and other published CRC gene signatures, as well as gene elements associated with intestinal stem cell biology and epithelial-to-mesenchymal transition (EMT). RNA was...
DeepTrain: A Programmable Embedded Platform for Training Deep Neural Networks

This paper presents, DeepTrain, an embedded platform for high-performance and energy-efficient training of deep neural network (DNN). The key architectural concept of DeepTrain is to develop a spatially homogeneous computing (and memory) fabric with temporally heterogeneous programmable data flows to optimize memory mapping and data reuse during different phases of training operation.The DeepTrain is demonstrated as an in-memory accelerator integrated in the logic layer of a 3-D memory module. A programming model and supporting architecture utilizes the flexible data flow to efficiently accelerate training of various types of DNNs. The cycle level simulation and synthesized design in 15 nm FinFET shows power efficiency of 500 GFLOPS/W, and almost similar throughput for a wide range of DNNs, including convolutional, recurrent, and mixed (CNN+RNN) networks.
Physician volume and discontinuation of rituximab during lymphoma treatment.

6593Background: Despite the high complexity of cancer therapies, studies evaluating provider-level volume and outcomes of systemic treatments are lacking. As rituximab was the first approved monocl...
SketchFix: a tool for automated program repair approach using lazy candidate generation

Manually locating and removing bugs in faulty program is often tedious and error-prone. A common automated program repair approach called generate-and-validate (G&V) iteratively creates candidate fixes, compiles them, and runs these candidates against the given tests. This approach can be costly due to a large number of re-compilations and re-executions of the program. To tackle this limitation, recent work introduced the SketchFix approach that tightly integrates the generation and validation phases, and utilizes runtime behaviors to substantially prune a large amount of repair candidates. This tool paper describes our Java implementation of SketchFix, which is an open-source library that we released on Github. Our experimental evaluation using Defects4J benchmark shows that SketchFix can significantly reduce the number of re-compilations and re-executions compared to other approaches and work particularly well in repairing expression manipulation at the AST node-level granularity.The demo video is at: https://youtu.be/AO-YCH8vGzQ.
Development of working memory in the male adolescent rat.

Working memory develops over the course of adolescence, and neuroimaging studies find development-associated changes in the activity of prefrontal cortical brain regions. Establishment of a rodent model of working memory development would permit more comprehensive studies of the molecular and circuit basis for working memory development in health and disease. Thus, in this study, working memory performance was compared between adolescent and adult male Sprague-Dawley rats using an operant-based, delay-match-to-sample working memory task. Adolescent and adult rats showed similar rates of learning the task and similar performance at a low cognitive load (delays ≤ 6 s). However, when the cognitive load increased, adolescents exhibited impaired working memory performance relative to adults, until postnatal day 50 when performance was not significantly different. Despite evidence that cannabinoids disrupt working memory, we found no effect of acute treatment with the cannabinoid receptor agonist, WIN55212,2, at either age. Moreover, expression of glutamate and GABA receptor subunits was examined in the prelimbic and infralimbic prefrontal cortex across development. NMDA receptor subunit GluN2B expression significantly decreased with age in parallel with improvements in working memory. Thus, we show evidence that rats can be used as a model to study the molecular underpinnings of working memory development.
IMPACT OF PATIENT FRAILTY ON ONE-YEAR MORTALITY ACROSS CHA2DS2-VASC SCORES: FROM THE TREAT-AF STUDY

The CHA2DS2-VASc score, validated in older and morbid cohorts, guides treatment decisions in patients with atrial fibrillation (AF). We previously found a claims-based frailty phenotype was associated with the CHA2DS2-VASc score and theorize that frailty may be an important driver of outcomes across
TCTAP C-134 How to Deal with Wire Induced Coronary Intramural Hematoma

### Patient Initials or Identifier Number ABM ### Relevant Clinical History and Physical Exam A 56 years old, diabetic, hypertensive, active smoker, presented with chest pain for 4 days. He had a history of percutaneous coronary intervention to Left anterior descending (LAD) and right coronary
Small mammals and paleovironmental context of the terminal pleistocene and early holocene human occupation of central Alaska

American Philosophical Society; University of Alaska Museum of the North; School of Anthropology, University of Arizona; Alaska State Historic Preservation Office; National Science FoundationNational Science Foundation (NSF) [BCS-1504654, PLR-1138811, PLR-0540235, PLR-1107631, PLR-1223119]
El ángel monstruoso: sobre la figura de Mignon en "Los años de Aprendizaje de Wilhem Meister" de Goethe

espanolEste articulo situa la figura de Mignon en los Anos de aprendizaje de Wilhelm Meister de Goethe en el contexto de la emergencia de un nuevo concepto hermeneutico de la “vida” –la “vida” entendida como una fuerza invisible que da forma a las criaturas vivas desde dentro– al final del siglo XVIII. Presentada de forma explicita como un “enigma”, el personaje de Mignon encarna problemas de diferenciacion –hombre/mujer, vivo/mecanico, espiritu/letra– creados por el intento por parte del vitalismo de concebir la naturaleza y la cultura como manifestaciones de una sola “vida”. El articulo propone que la funcion de Mignon no es la de simbolizar un ideal estetico o politico-moral mas elevado, sino delinear los limites de la forma biologica y social en la novela de Goethe. El ensayo concluye con unas reflexiones criticas sobre el intento de Goethe de convertir la excentricidad normativa de Mignon en la fuente de fascinacion estetica. EnglishThe article places the figure of Mignon in Goethe’s Wilhelm Meisters Lehrjahre in the context of the emergence of a new hermeneutic concept of “life” –“life” understood as an invisible force that shapes living creatures from within– at the end of the eighteenth century. Explicitly introduced as a “riddle”, Mignon’s enigmatic character is shown to embody problems of differentiation –man/woman, living/mechanical, spirit/letter– created by vitalism’s attempt to conceive of nature and culture as manifestations of a single “life”. The article suggests that Mignon’s function is not to symbolize a higher aesthetic or moral-political ideal but to mark out the limits of biological and social form in Goethe’s novel. The essay ends with critical reflections on Goethe’s attempt to turn Mignon’s normative eccentricity into the source of aesthetic fascination.
Protein and Antibody Delivery into Difficult-to-Transfect Cells by Polymeric Peptide Mimics

Intracellular protein delivery using simple noncovalent carriers is an emerging field advancing the study of intracellular pathways and novel therapeutics. Here, we directly compare green fluoresce...
Expression of lysine-mediated neuropeptide hormones controlling satiety and appetite in broiler chickens.

Abstract Lysine is the second most limiting amino acid after methionine and is considered the most limiting amino acid for growth in poultry. Lysine requirement for broiler chickens has changed over the years. Leptin and adiponectin represent 2 adipokines that mediate metabolism by eliciting satiety effects whereas ghrelin peptide hormone influences appetite. We hypothesize that this affects growth performance of chicks. This study evaluates the effect of varying dietary lysine homeostasis on performance of broiler chickens through satiety- and appetite-mediating hormones. In 3 replications, 270 one-day-old chicks were reared for 8 wk feeding on diets comprising 0.85, 1.14, and 1.42% lysine during the starter period and 0.75, 1.00, and 1.25% lysine during the grower period. These concentrations of lysine represent 75% (low lysine), 100% (control), and 125% (high lysine) of National Research Council recommendation for broiler chickens. Feed and water were provided for ad libitum consumption. At 8 wk of age, liver, pancreas, brain, and hypothalamus tissues were collected from 18 birds randomly selected from each treatment, snap frozen in liquid nitrogen, and stored at −80°C until use. Total RNA was extracted, and cDNA was synthesized for quantitative real-time PCR assays. Low lysine concentration caused slow growth and high mortality. There was significant upregulation of ghrelin in the hypothalamus and pancreas, and leptin and adiponectin in the hypothalamus and liver, and downregulation of ghrelin in the intestines. At low lysine concentrations, adiponectin was not expressed in both pancreas and intestines. High lysine concentration exhibited increased growth, upregulation of ghrelin in the liver, and downregulation of ghrelin in the intestines, and both adiponectin and leptin in the liver. The expression of ghrelin was negatively correlated with the expression of adiponectin and leptin (P
Economic Strain Deteriorates While Education Fails to Protect Black Older Adults Against Depressive Symptoms, Pain, Self-rated Health, Chronic Disease, and Sick Days

Background A large body of empirical evidence on Minorities' Diminished Returns (MDRs) suggests that educational attainment shows smaller health effects for Blacks compared to Whites. At the same time, economic strain may operate as a risk factor for a wide range of undesired mental and physical health outcomes in Black communities. Aim The current study investigated the combined effects of education and economic strain on the following five health outcomes in Black older adults in underserved areas of South Los Angeles: depressive symptoms, number of chronic diseases, pain intensity, self-rated health, and sick days. Methods This cross-sectional study included 619 Black older adults residing in South Los Angeles. Data on demographic factors (age and gender), socioeconomic characteristics, economic strain, health insurance, living arrangement, marital status, health behaviors, depressive symptoms, pain intensity, number of chronic diseases, sick days, and self-rated health were collected. Five linear regressions were used to analyze the data. Results Although high education was associated with less economic strain, it was the economic strain, not educational attainment, which was universally associated with depressive symptoms, pain intensity, self-rated health, chronic diseases, and sick days, independent of covariates. Similar patterns emerged for all health outcomes suggesting that the risk associated with economic strain and lack of health gain due to educational attainment are both robust and independent of type of health outcome. Conclusion In economically constrained urban environments, economic strain is a more salient social determinant of health of Black older adults than educational attainment. While education loses some of its protective effects, economic strain deteriorates health of Black population across domains. There is a need for bold economic and social policies that increase access of Black communities to cash at times of emergency. There is also a need to improve the education quality in the Black communities.