cssi/SciSciGPT-SciSciNet huggingface dataset:
Near-field dipole radiation dynamics through FDTD modeling

We use finite-difference time-domain (FDTD) numerical simulations to study horizontal dipole radiation mechanisms and patterns near half-space interfaces. Time snapshots illustrating propagation of wavefronts at an instance in time are included with antenna patterns to provide a visualization tool for understanding antenna radiation properties. Near-field radiation patterns are compared with far-field asymptotic solutions and the effects of electrical properties, antenna height, and observation distance are investigated through numerical simulations. Numerical simulations show excellent agreement with measured data collected over a water-filled tank. Near-field H-plane radiation patterns are broader and contain radiation maxima beyond the critical angle predicted by far-field solutions. A large amplitude E-plane radiation lobe is located directly below the antenna in all simulations, while the two large amplitude sidelobes are less distinct and occur at larger incidence angles than predicted by far-field solutions. Radiation patterns resemble far-field solutions by a distance of 10 wavelengths, except near the critical angle where H-plane radiation maxima and E-plane sidelobes occur at larger incidence angles than predicted by far-field solutions.
Glycoprotein degradation: Glycosidases in fibroblasts transformed by oncogenic viruses

Abstract Fibroblasts transformed by oncogenic viruses were found to have greater enzymic activities of 7 glycosidases on a cell or protein basis than two non-transformed cell lines. Two glycosidases studied (α- d -fucosidase and β- d -xylosidase) were not found in any of the fibroblast cells or HeLa cells. The glycosidase with the greatest activity in all the cells studied was N -acetyl-β- d -glucosaminidase. The most pronounced differences were found with α- d -glucosidase in which increases in activity in the transformed cells ranged from 3.1 to 4.5 fold over the non-transformed cell lines.
Electron microscopic observations on the normal and denervated adrenal medulla of the rat.

Mulon (1905) first observed that adrenal medullary cells when fixed with osmic acid exhibit intracellular osmiophile granules. Assuming these bodies to be comparable with the chromaffin granules of Hultgen and Anderson (1899) and Kohn (1902), he claimed that the osmic acid staining reaction was a specific histochemical test for adrenalin. Bennett (1941) disputed such an absolute specificity on the grounds that, besides adrenaline itself, other reducing substances (many of them polyphenol precursors of adrenaline) were blackened by osmic acid. Since osmic acid has recently proved effective as a tissue fixative for electron microscopic study (Porter, Claude and Fullam 1945: Palade 1952: Dalton 1955), it seemed especially relevant to examine the adrenal medulla by this method. MATERIAL AND METHODS The Normal Medulla. During the electron microscopic study of the rat adrenal cortex (Lever (a) in press) the medulla was concurrently examined in some 25 animals. In addition 12 more normal glands were obtained as ...
Disability Outcomes Following Inpatient Rehabilitation for Stroke

The Uniform Data System for Medical Rehabilitation and the Functional Independence Measure have been utilized to evaluate outcomes of patients undergoing initial comprehensive inpatient medical rehabilitation for stroke. The Functional Independence Measure total, domain, subscale, and item scores were used to monitor patients during and following rehabilitation. The benchmark function values and times from stroke onset were reported, and the functional areas of physical therapy participation were noted. It is expected that these benchmarks may serve as a baseline for future study of the extent and rate of functional return following stroke and for strengthening the scientific basis of rehabilitation practice, leading to improved effectiveness and efficiency of rehabilitation therapy.
Carbohydrate versus fat intake: differing patterns of macronutrient selection in two inbred mouse strains

As a first step toward developing a mouse model to characterize genetic factors linked to the preferential intake of dietary carbohydrate or fat, we have identified two mouse strains that exhibit distinctly different patterns of macronutrient selection. Macronutrient selection was evaluated in AKR/J and SWR/J mice, two strains that have been characterized previously for their sensitivity to high-fat dietary obesity. Mice were adapted to a self-selection protocol in which separate carbohydrate, fat, and protein sources were simultaneously available. AKR/J mice ate 30% more calories than the SWR/J mice. Furthermore, strain comparisons revealed a significantly higher proportion of fat intake by the AKR/J mice (69 vs. 28%), and in the SWR/J mice a significantly higher intake of carbohydrate (62 vs. 24%). The mice were then returned to a standard chow diet for 10 wk. These mice subsequently were allowed to self-select from two composite energy diets (carbohydrate and protein, or fat and protein). Once again, AKR/J mice selected a greater proportion of energy from the fat/protein diet (85%) than did the SWR/J strain (32%). These findings suggest a possible relationship between sensitivity to dietary obesity and fat selection.
Looking Back at the Land: Discourses of Agrarian Morality in Telugu Popular Cinema and Information Technology Labor

This article takes Anand Pandian's notion of “agrarian civility” as a lens through which we can begin to understand the discourses of morality, merit, and exclusivity that color both popular Telugu film and Telugu IT workers' understanding of their technologically enabled work. Popular Telugu film binds visual qualities of the landscape and depictions of heroic technological proficiency to protagonists' internal dispositions and moralities. I examine the portrayal of the landscape and of technology in two Telugu films: Dhee…kotti chudu, and Nuvvostanante Nenoddantana, in order to more clearly discern the nature of this agrarian civility and—more importantly for thinking about Telugu IT workers— to make explicit its attribution of morality to “merit” and to technological proficiency.
Metabolic properties of quinidine; effects of quinidine sulfate on anaerobic carbohydrate metabolism of rat diaphragm.

Summary1. Quinidine sulfate at a concentration of 1 × 10-3 M strongly inhibits the uptake of glucose and fructose by intact rat diaphragm under anaerobic conditions. 2. Quinidine is without effect on endogenous anaerobic lactic acid production by rat diaphragm. 3. Glucose at a concentration of 1 mg/ml or 4 mg/ml markedly stimulates anaerobic glycolysis while fructose at a concentration of 5 mg/ml produces only a slight stimulation. 4. Stimulation of glycolysis by glucose or fructose is abolished by 1 × 10-3 M quinidine and partially inhibited by 5 × 10-4 M quinidine. 5. It is suggested that quinidine inhibits glucose or fructose uptake prior to the step at which these sugars and glycogen share a common metabolic pathway.
PROMOTING MODULARITY IN EVOLUTIONARY DESIGN

Evolutionary design systems apply principles inspired from biological evolution to automate machine design. These systems have been shown to generate simple designs for simple tasks – but their practical ability to scale up to higher complexities remains questioned. One of the keys to accomplishing higher-level evolutionary design is the ability of the process to identify and reuse knowledge discovered at lower levels, thus scaling its search capacity. One way to capture this knowledge is in the form of reusable building blocks – modules. In this paper we define modularity and discuss several approaches to promoting modularity in evolutionary design systems. In particular, we propose a new mechanism that can enhance modularization. This mechanism is based on the observation that designs that exhibit modularity have higher adaptability and consequently have better survival rates under changing requirements. Contrary to other techniques, this is a weak (indirect) formulation that does not require representation of partial solutions or definition of a genotype from which a design is developed. We demonstrate this principle on an
COMPARATIVE ASPECTS OF AFRICANA PHILOSOPHY AND THE CONTINENTAL-ANALYTIC DIVIDE

Critical engagement involving philosophers trained in continental and analytic traditions often takes its purpose to be a reconciliation of tensions arising from differences in style, or method. Critical engagement in Africana philosophy, however, is rarely focused on method, style, or orientation because philosophic research in this field, regardless of orientation, has had to accommodate its empirical grounding in disciplines outside of philosophy. I focus primarily on the comparative dimensions of three important strands of this research: (1) a history of ideas, (2) a problem-orientation, and (3) a sub-area specialization, to indicate why a need to reconcile tensions between continental and analytic orientations has very little currency in Africana philosophy. Socio-economic problems faced by African-descended people require multiple perspectives to accommodate the wide variety of diasporic social contexts for a given proposal. I employ a selection of cases to illustrate how Africana philosophy benefits from an interplay of many intersecting factors and that, as an interdisciplinary area of research with a commitment to the incorporation of multiple perspectives, it fosters cross-pollination and hybridization of continental and analytic traditions.
What constitutes liver failure after transjugular intrahepatic portosystemic shunt creation? A proposed definition and grading system.

ABSTRACT ABSTRACT ABSTRACT Background and rationale for the study Background and rationale for the study Background and rationale for the study Background and rationale for the study Background and rationale for the study. There is currently no definition of post-transjugular intrahepatic portosystemic shunt (TIPS) liver failure (PTLF), which constitutes a barrier to standardization of TIPS results reporting and limits the ability to compare liver failure incidence across clinical studies. This descriptive study proposes and preliminarily tests the performance of a PTLF defi- nition and grading system. Results.PTLF was defined by ≥ 3-fold bilirubin and/or ≥ 2-fold INR elevation associated with clinical outcomes of prolonged hospitalization/increase in care level (grade 1), TIPS reduction or liver transplantation (grade 2), or death (grade 3) within 30-days of TIPS. PTLF incidence was 20% (grades 1, 2, 3: 10%, 3%, 8%) among 270 TIPS cases, and the sche- me identified patients at increased risk for morbidity and mortality with a statistically significant difference in clinical outcomes bet- ween PTLF and non-PTLF groups (P<0.0001). Conclusions. Conclusions. Conclusions. Conclusions.In conclusion, the PTLF definition and classification scheme put forth distributes patients into unique risk groups. PTLF grading may thus be useful for standardization of TIPS results reporting.
Refining Statin Prescribing in Lower-Risk Individuals: Informing Risk/Benefit Decisions.

Abstract Guidelines from the American College of Cardiology/American Heart Association, as well as those from the Veterans Affairs/Department of Defense and the Joint British Societies all recommended treating more people with statins than previous guidelines. In each guideline, the decision-making process began with an assessment of overall cardiovascular risk. Each group proposed updated treatment thresholds, and all of them lowered the threshold compared with earlier guidelines. Since release of these new guidelines in 2013 and 2014, additional evidence has emerged to suggest a rationale for extending statin consideration to an even larger proportion of asymptomatic adults—even those with a 10-year atherosclerotic cardiovascular disease risk below 7.5%. This review discusses new findings since 2013 and proposes strategies emanating from the current guidelines to help clinicians and patients make more informed decisions about long-term statin use, especially pertinent to lower-risk patients.
Plan for the Future: Advancing Ecological Engineering Through Science, Conceptual Design, and Community Resilience Building

By the latter part of the twenty-first century, the globe and all societies present will be faced with compelling environmental and climatic circumstances requiring hard choices and tradeoffs to maintain standards of living and viable environmental conditions. One opportunity to shift this reality is through greater understanding of the services and benefits provided by ecosystems as a cost effective means of regulating the impacts of natural disasters and climatic change. This will require broad, collaborative exploration of the science, policy, economics, and funding needed to mainstream the use of nature-based solutions via ecological engineering and design. Clearly there is unprecedented global interest and demand for resilience to disasters and climate change that recognizes the contribution ecosystems can and are making to reduce risk at all scales. The comprehensive overview, conceptual framework, recommendations, and supportive case studies presented herein are intended to move the emerging field of ecological engineering and design forward as an imperative for humanity.
4-H Afterschool – Making an Impact

4-H Afterschool is making a positive impact on youth, families, and their communities. Utah State University Extension has implemented a 4-H Afterschool club at four elementary schools in low-income neighborhoods. At each of the sites, 4-H offers sixteen different project clubs. Survey results indicate that the 4-H Afterschool program is building positive social skills in the youth, providing positive alternatives to idleness and antisocial behavior, and supporting parents in the primary role of care giving. The Afterschool clubs incorporate project activities, a service learning component, and a final showcase for the parents. Youth development professionals, using the experiential learning model of 4-H, can affect positive change within their communities by implementing a 4-H Afterschool program.
Metadata provide insights on patterns of epiparasitism in mistletoes (Santalales), an overlooked topic in forest biology1

Mistletoes are aerial-branch parasites belonging to one of five families in the Santalales. Usually, mistletoe hosts are autotrophic, but if the hosts themselves are parasitic, the plant parasitizi...
Treatment of Adults with Idiopathic Recurrent Pericarditis: Novel Use of Immunotherapy

Idiopathic recurrent pericarditis (IRP) can be challenging to treat. Even after guideline-directed first-line treatment consisting of aspirin (ASA) or a nonsteroidal antiinflammatory drug (NSAID) in combination with colchicine therapy, recurrences still occur in greater than 20% of patients. Many patients then require treatment with long-term corticosteroids, which is not a favorable option due to their short- and long-term adverse effects. Because it is theorized that the pathophysiology of IRP may possess autoimmune sequelae, the use of immunotherapy for the treatment of IRP has emerged. In this review, we describe the literature associated with immunotherapy used to treat IRP in an adult population as well as provide an overview of the safety and monitoring parameters for each agent. The most common immunotherapies used after patients have had multiple recurrences of IRP are anakinra, intravenous immunoglobulin (IVIG), and azathioprine. In most cases, these immunotherapies are adjunctive therapy, with the goal of tapering and discontinuing immunosuppressive corticosteroids. After reviewing the data, anakinra resulted in more patients discontinuing corticosteroids and prevented further recurrences of pericarditis. IVIG resulted in symptom resolution and no further recurrences in most of the patients. Azathioprine was associated with more than half of patients becoming recurrence free; however, many patients required a restart of corticosteroids due to recurrence. Clinicians should be aware of the adverse effects of immunotherapy, ranging from mild gastrointestinal events to risk of infection and serious blood dyscrasias that may require diligent monitoring. The use of immunotherapy for the treatment of adults with IRP should be restricted to patients who have multiple recurrences. Ideally, immunotherapy would be adjunctive to first-line combination therapy with ASA/NSAID plus colchicine, with the goal of tapering and discontinuing immunosuppressive corticosteroids. Furthermore, clinicians should consider cost, drug-drug and drug-disease interactions, and safety, as well as the quality of the retrospective evidence before considering any immunotherapy.
Web-based, multi-platform, centralized, offline-compatible supply chain management system for emergency responses

The efficiency of humanitarian aid supply chains is critical to effective emergency response. In addition, a sustainable supply chain network facilitates the rapid recovery of devastated areas and provides relief for the affected populations. Thus, an efficient, reliable and sustainable emergency supply chain management system plays a critical role in the humanitarian relief operations. Currently, a typical NGO ERP (enterprise resource planning) system does not address the specific needs of emergency humanitarian relief functions. Without an emergency supply chain management system, the lack of coordination and potential human errors will cause unnecessary delays and wastes in resources, which jeopardizes the safety, and sometimes survival, of affected people. In addition, tracking relief materials from donor resources all the way to distribution to target beneficiaries is important for accountability and transparency. In this project, Purdue University and Catholic Relief Services (CRS) are co-designing a web-based, multi-platform, centralized, offline-compatible electrical emergency response system. This system is capable of connecting all global warehouses across different country programs, requesting and approving relief materials, checking inventory levels, tracking relief materials from donors to beneficiaries, and automatically generating accounting and beneficiary reports. This application will help NGOs form efficient, reliable and sustainable distribution plans for emergency responses with the most updated information.
Assessment of Methods for the Measurement of Wood Fuel Compositions

The composition of processed wood fuels, such as pellets, is important, since large quantities of pellets are used to heat buildings and generate electricity. Prior work identified heavy metal contaminants in pellets as a result of waste wood being part of the input materials. Preparation methods for the analysis of the elemental composition of wood fuels with ICP-MS were evaluated using standard reference materials (SRM) and real wood pellet samples. The effect of different degrees of grinding (10–20 μm and 60–100 μm) on the homogeneity of the resulting samples was investigated. The finer-ground samples (particle size 10–20 μm) demonstrated good homogeneity. The amount of mass required for digestion was evaluated based on the relative mean error (%) for the elemental analyses for both direct HNO3-H2O2 and Ash-HNO3-H2O2 digestion methods. Well ground, larger pellet samples (10–20 μm and ∼1.0 g) demonstrated good agreement between two digestion methods. The precision of the analysis with ICP-MS was evaluat...
Effect of an Advanced Pharmacy Practice Experience on Medication Therapy Management Services in a Centralized Retail Pharmacy Program

BACKGROUND: Medication therapy management (MTM) delivery is increasingly important in managed care. Successful delivery positively affects patient health and improves Centers for Medicare & Medicaid Services star ratings, a measure of health plan quality. As MTM services continue to grow, there is an increased need for efficient and effective care models. The primary objectives of this project were to describe the delivery of MTM services by fourth-year Advanced Pharmacy Practice Experience (APPE) students in a centralized retail pharmacy system and to evaluate and quantify the clinical and financial contributions of the students. The secondary objective was to describe the engagement needed to complete comprehensive medication reviews (CMRs) and targeted interventions. PROGRAM DESCRIPTION: From May 2015 to December 2015, thirty-five APPE students from the University of Colorado Skaggs School of Pharmacy provided MTM services at Albertsons Companies using the OutcomesMTM and Mirixa platforms. Students del...
Geometric Q Charts for High Quality Processes

The geometric distribution based on the inverse binomial method of sampling is used to define Q statistics for the case when the process fallout p is known and when it is not known in advance of sampling. The effectiveness to detect shifts in p of four ..
You’ve Been Tricked! A User Study of the Effectiveness of Typosquatting Techniques

The deceitful practice of Typosquatting involves deliberately registering Internet domain names containing typographical errors that primarily target popular domain names, in an effort to redirect users to unintended destinations or steal traffic for monetary gain. Typosquatting has existed for well over two decades and continues to be a credible threat to this day. While much of the prior work has examined various typosquatting techniques and how they change over time, none have considered how effective they are in deceiving users. In this paper, we attempt to fill in this gap by conducting a user study that exposes subjects to several uniform resource locators (URLs) in an attempt to determine the effectiveness of several typosquatting techniques that are prevalent in the wild. We also attempt to determine if the security education and awareness of cybercrimes such as typosquatting will affect the behavior of Internet users.
Feminist men?: examining men’s feminist self-identification, activism and the impact of language

Men’s participation is essential to achieving gender equality. This study addresses research gaps in the under-studied area of men’s participation in gender equality activism. We demonstrate, among...
A REMARK ON ULRICH AND ACM BUNDLES

Abstract I show that on any smooth, projective ordinary curve of genus at least two and a projective embedding, there is a natural example of a stable Ulrich bundle for this embedding: namely the sheaf B X 1 of locally exact differentials twisted by O X ( 1 ) given by this embedding and in particular there exist ordinary varieties of any dimension which carry Ulrich bundles. In higher dimensions, assuming X is Frobenius split variety I show that B X 1 is an ACM bundle and if X is also a Calabi–Yau variety and p > 2 then B X 1 is not a direct sum of line bundles. In particular I show that B X 1 is an ACM bundle on any ordinary Calabi–Yau variety. I also prove a characterization of projective varieties with trivial canonical bundle such that B X 1 is ACM (for some projective embedding datum): all such varieties are Frobenius split (with trivial canonical bundle).
How and Why Sex Differences Evolve, with Spatial Ability as a Paradigm Example

When articulated in genetic terms, Darwin’s (1859) theory of evolution by natural selection is the most powerful tool we have for explaining why living things are as they are (Fisher, 1958; Dawkins, 1982). The theory is powerful because its prerequisite conditions are minimal and its implications ubiquitous. Natural selection will be at work anywhere entities make imperfect copies of themselves. For the kinds of organisms we know well, the imperfections of interest are mutations. These chance errors in gene copying create gene variants -alleles- at each chromosomal locus, alleles that are inevitably in competition with one another. An allele will win the competition, eventually replacing its competitors, if it has effects that cause it to be copied at a higher rate than any of its allelic alternatives. In this way genes that most favorably affect their own copying rates become common. The manifest traits of organisms are simply the allelic effects that led to maximal rates of gene copying.1
Practice Patterns of Dentist Anesthesiologists in North America

This study provides trends in the discipline of dental anesthesiology. A questionnaire-based survey was sent to 338 members of the American Society of Dentist Anesthesiologists to evaluate practice...
Good intentions are not enough: how informatics interventions can worsen inequality

Health informatics interventions are designed to help people avoid, recover from, or cope with disease and disability, or to improve the quality and safety of healthcare. Unfortunately, they pose a risk of producing intervention-generated inequalities (IGI) by disproportionately benefiting more advantaged people. In this perspective paper, we discuss characteristics of health-related interventions known to produce IGI, explain why health informatics interventions are particularly vulnerable to this phenomenon, and describe safeguards that can be implemented to improve health equity. We provide examples in which health informatics interventions produced inequality because they were more accessible to, heavily used by, adhered to, or effective for those from socioeconomically advantaged groups. We provide a brief outline of precautions that intervention developers and implementers can take to guard against creating or worsening inequality through health informatics. We conclude by discussing evaluation approaches that will ensure that IGIs are recognized and studied.
Sister Chromatid Exchanges

Sister chromatid exchanges (SCEs) represent the interchange of DNA replication products at apparently homologous loci. These exchanges presumably involve DNA breakage and reunion, although little is known about the molecular basis of sister chromatid exchange formation, and information about the biological significance of exchanges is largely circumstantial. In spite of these uncertainties, analysis of sister chromatid exchange formation in cytological systems has already provided information about chromosome structure and has been used to detect the effects of clastogens and to differentiate between chromosome fragility diseases.
Enriching Communicative Environments: Leveraging Advances in Neuroplasticity for Improving Outcomes in Neurogenic Communication Disorders

Purpose Research manipulating the complexity of housing environments for healthy and brain-damaged animals has offered strong, well-replicated evidence for the positive impacts in animal models of ...
Going Live and Conclusions

User training usually requires a phased approach paralleling the life cycle of the new product. Some parts of training can take place early, but a huge portion will likely occur as the system approaches the go-live phase. Training may also need to be repetitive and completed among different management and staff users. Training can be shared, that is, some being done by internal users, others by the third-party vendors or by the product company. There is also the concept of “train-the-trainer,” where third-party trainers, train internal users to take on the major parts of training among the user staffs. This chapter also covers documentation, which is often considered a part of the training process. The contribution of the organization’s IT department is always one of debate. Many organizations consider the IT department as the “owner” of the effort and expect that IT personnel will act as the main department handling every aspect of the implementation. Other organizations adapt a user-controlled effort, where the IT department is essentially used to accomplish specific tasks. The later approach has a major advantage in that the business becomes the owner, and effectively should be since they are the beneficiaries of the application software product. In yet another approach, the IT executive takes on a leadership role, where IT is responsible from an executive level, but the business department still owns the responsibility to get the product implemented and absorbed by the organization. This chapter represents the pinnacle of the project completion. Sections cover key issues to be coordinated among the stakeholders, business partners, and vendors to ensure that everything is ready for production. The go-live step should also consider the handling of problems, including application bugs that need to be fixed or worked around (finding an alternative way of doing something in the system). The go-live phase must also address final sign off with vendors and stakeholders.
Automatically identifying social isolation from clinical narratives for patients with prostate Cancer.

Social isolation is an important social determinant that impacts health outcomes and mortality among patients. The National Academy of Medicine recently recommended that social isolation be documented in electronic health records (EHR). However, social isolation usually is not recorded or obtained as coded data but rather collected from patient self-report or documented in clinical narratives. This study explores the feasibility and effectiveness of natural language processing (NLP) strategy for identifying patients who are socially isolated from clinical narratives. We used data from the Medical University of South Carolina (MUSC) Research Data Warehouse. Patients 18 years-of-age or older who were diagnosed with prostate cancer between January 1, 2014 and May 31, 2017 were eligible for this study. NLP pipelines identifying social isolation were developed via extraction of notes on progress, history and physical, consult, emergency department provider, telephone encounter, discharge summary, plan of care, and radiation oncology. Of 4195 eligible prostate cancer patients, we randomly sampled 3138 patients (75%) as a training dataset. The remaining 1057 patients (25%) were used as a test dataset to evaluate NLP algorithm performance. Standard performance measures for the NLP algorithm, including precision, recall, and F-measure, were assessed by expert manual review using the test dataset. A total of 55,516 clinical notes from 3138 patients were included to develop the lexicon and NLP pipelines for social isolation. Of those, 35 unique patients (1.2%) had social isolation mention(s) in 217 notes. Among 24 terms relevant to social isolation, the most prevalent were “lack of social support,” “lonely,” “social isolation,” “no friends,” and “loneliness”. Among 1057 patients in the test dataset, 17 patients (1.6%) were identified as having social isolation mention(s) in 40 clinical notes. Manual review identified four false positive mentions of social isolation and one false negatives in 154 notes from randomly selected 52 controls. The NLP pipeline demonstrated 90% precision, 97% recall, and 93% F-measure. The major reasons for a false positive included the ambiguities of the experiencer of social isolation, negation, and alternate meaning of words. Our NLP algorithms demonstrate a highly accurate approach to identify social isolation.
Microwave Absorption of Magnetic Antidot Arrays

Three antidot arrays with FeNi alloy thickness of 20, 50 and 100 nm have been patterned using magnetron sputtering followed by the electron-beam lithography and lift-off technique. Ferromagnetic resonance technique was used to study dynamic properties of the antidot arrays. These results were compared with the measurements of continuous films with the same composition and thickness. Two distinct resonant fields have been observed for the bias field aligned with the edges of the square holes. Resonance peaks shifted towards each other and eventually merged when the in-plane bias field was rotated towards diagonal of the squares. This dependence has been explained in terms of magnetostatic energy associated with the square holes. The magnitude of this effect was decreasing for the arrays with the reduced thickness. The perpendicular and lateral quantized standing spin wave modes were detected in the reference films and the antidot arrays due to the perpendicular and lateral dimensional confinements.
Surviving the storm: Avoidant coping, helping behavior, resilience and affective symptoms around a major hurricane-flood.

Abstract Background As extreme weather events increasingly affect the global population, it is valuable to understand their impacts on mental health. Extending upon previous theory and research, the current study examined a hypothesized framework of direct and indirect pathways. Exposure and psychosocial resource factors at the time of the hurricane/flood were expected to help explain post-disaster behavioral responses, such as avoidant coping, positive coping, and helping behaviors, which, in turn, would help account for post-traumatic stress symptoms (PTSS) and depressive symptoms (DS). Methods Survey data were collected from adult survivors (n = 801) of Hurricane Harvey 1–3 months post-disaster. PTSS, DS, and needing help were common, and loss/disruption and helping behavior were widespread. Structural equation modeling was used to examine the hypothesized framework. Results Models accounted for substantial variance in PTSS (70%) and DS (61%), with immediate loss/disruption, low self-reported resilience, and avoidant coping showing the strongest associations with symptoms. As predicted, results provided support for several modeled indirect pathways through avoidant coping to PTSS and DS. Further, helping behavior was consistently associated with increased PTSS, but not DS. Limitations Cross-sectional design and online data collection methods precluded testing of causal directionality and confirming clinical diagnoses. Conclusions The current study represents a step toward elucidating potential mediators of avoidant coping and how helping behavior might relate to post-disaster psychopathology. Individuals in heavily hurricane/flood-exposed areas who have low psychosocial resources (social support and resilience) might be most vulnerable and most in need of intervention.
Cefepime-induced Non-convulsive Status Epilepticus (P2.5-022)

Objective: To highlight the importance of recognizing Non-Convulsive Status Epilepticus (NCSE) as a serious complication in patients with encephalopathy while being treated with Cefepime. Background: Cefepime is a 4th generation cephalosporin which is widely used to treat Gram-positive and Gram-negative bacterial infections and is frequently used during hospital admissions. Impaired renal function increases the risk for Cefepime-induced neurotoxicity and symptoms range from disorientation, aphasia, myoclonus, status epilepticus, to coma and death. A 60-year-old female (with hypertensive emergency and respiratory failure requiring intubation) was transferred to the Neuroscience intensive care unit (NSICU) due refractory NCSE. She was being treated with Cefepime 2 gm three times a day for sepsis in a community hospital despite renal impairment. Due to persistent altered consciousness (Glasgow coma scale 6), she had undergone electroencephalographs (EEGs) which were suggestive of NCSE for which levetiracetam, lacosamide and fosphenytoin were sequentially started, however, cefepime was continued, patient was considered refractory to treatment and was transferred to our NSICU. Continuous EEG at the NSICU revealed 2–2.5 Hz generalized periodic discharges (GPDs) indicative of cefepime-induced NCSE. Cefepime was discontinued, all antiepileptics except Levetiracetam were held and continuous renal replacement therapy was initiated. Over the course of the next 6 hours, GPDs were noted to dissipate on continuous EEG and were replaced with diffuse background slowing and generalized rhythmic delta activity (GRDA). Mental status gradually improved over the next 3 days with more wakefulness and patient being able to follow simple 1-step commands crossing midline. Patient eventually was extubated and transferred to the neurology floor. Design/Methods: Not applicable Results: Not applicable Conclusions: NCSEis an under-recognized complication of cefepime toxicity. Dose adjustment or avoidance of cefepime is of utmost importance when managing patients with end stagerenal disease. Early recognition is vital to improve outcome. Disclosure: Dr. Hollen has nothing to disclose. Dr. Muzammil has nothing to disclose. Dr. Dayyoub has nothing to disclose.
Reported Court Structuring Bills

Measures that were reported out from the judiciary committee that structure the federal judiciary are analyzed. Similar to the court curbing chapter, a historical and quantitative analysis is undertaken to determine the potential causes of judicial structuring. Separation of powers explanations are also explored. The historical account suggests that structuring may be caused by attempts to “stack the deck” with such measures being reported out during ideologically divisive times with the Court. An alternate explanation is that Congress may add judges and/or courts based on the administrative needs of the federal judiciary. The quantitative results support the ideological/partisan explanation.
Cancer immunotherapy comes of age and looks for maturity.

As Nature Communications celebrates a 10-year anniversary, the field has witnessed the transition of cancer immunotherapy from a pipe dream to an established powerful cancer treatment modality. Here we discuss the opportunities and challenges for the future.
Design, construction and utilization of a university plasma laboratory

We present the elements required to construct two devices used in an undergraduate plasma physics laboratory. The materials and construction costs of the sources, the vacuum systems and probe drives and electrical circuits are presented in detail in the text and the first appendix. We also provide the software for probe motion and data acquisition as well as the electrical schematics for key components. Experiments which have been performed are listed and two (resonance cones and whistler waves) are described in greater detail. The machines are flexible and original research is possible.
Correction to : Estimating measurement uncertainty on stress-strain curves from SHPB

Equation (12) in the original article [1] gives the strain from the measured voltage on a full bridge configuration of the four strain gages. The full-bridge is intended to measure tension-compression strain (type III full-bridge), the correct equation is therefore [2]
Common Fungal Infections

Fungal infections of the lung are commonly seen by practicing pathologists. Typically caused by inhalation of fungal organisms (spores or hyphae), these infections can be broadly classified into two categories: endemic fungi, which typically infect immunocompetent hosts (but may also infect immunocompromised patients), and opportunistic fungi, which only infect immunocompromised patients. This chapter reviews six of the most common lung fungal infections seen in North America.
Association of Highly Restrictive State Abortion Policies With Abortion Rates, 2000-2014.

Importance Although abortion is common in the United States, patients face substantial barriers to obtaining an abortion. Recently enacted abortion restrictions pose such barriers. Objectives To assess the association between a state legislative climate that is highly restrictive toward abortion provision and the abortion rate and to evaluate whether distance to a facility providing abortion care mediates the association between legislative climate and the abortion rate. Design, setting, and participants This cohort study examined county-of-residence abortion rates from all states that publicly provided them and used data on abortion restrictions, facility locations, and county demographic characteristics for the years 2000 to 2014. The association between legislative climate and abortion rates was evaluated using propensity score-weighted, linear regression difference-in-difference analysis. All models included state and year fixed effects and standard errors adjusted for state-level clustering. Exposures Highly restrictive legislative climate, defined as having at least 3 of 4 types of abortion restrictions; distance to a high-volume facility providing abortion care (ie, performing ≥395 abortions per year) in miles. Main outcomes and measures County-level abortion rate, defined as abortions per 1000 women per year. Results Abortion rate data were obtained from 1178 counties in 18 states for a median of 12.5 years (range, 5-14). The median abortion rate was 2.89 per 1000 women (interquartile range, 1.71-4.46 per 1000 women). A highly restrictive legislative climate, when compared with a less restrictive one, was associated with 0.48 fewer abortions per 1000 women (95% CI, -0.92 to -0.04 abortions per 1000 women; P = .03). Adjusted for distance to a facility providing abortion care, a highly restrictive legislative climate was associated with 0.44 fewer abortions per 1000 women (95% CI, -0.85 to -0.03; P = .04). Each mile to a facility was associated with 0.02 fewer abortions per 1000 women (95% CI, -0.03 to -0.01 abortions per 1000 women; P = .003). Legislative climate was not significantly associated with distance to a facility providing abortion care (change in distance associated with highly restrictive climate, -2.73 [95% CI, -6.02 to 0.57] miles; P = .10). Conclusions and relevance This study provides evidence that a state legislative climate that is highly restrictive toward abortion provision is associated with a lower abortion rate. The cumulative effect of restrictive policies may pose a barrier to abortion access.
First-Order Learning Models With the GDINA: Estimation With the EM Algorithm and Applications:

In learning environments, understanding the longitudinal path of learning is one of the main goals. Cognitive diagnostic models (CDMs) for measurement combined with a transition model for mastery m...
University Faculty Salaries: Comparing Patterns of Gender Inequity to Those in the General Workforce

Patterns of gender inequity seen in the general workforce also occur among university faculty, despite faculty having strong similarities in education and job description. Identifying causes for these patterns and eliminating barriers for women in academia could set the example and promote gender equity in the general population.
Circadian rhythms and the gut microbiome synchronize the host’s metabolic response to diet

The molecular circadian clock and symbiotic host-microbe relationships both evolved as mechanisms that enhance metabolic responses to environmental challenges. The gut microbiome benefits the host by breaking down diet-derived nutrients indigestible by the host and generating microbiota-derived metabolites that support host metabolism. Similarly, cellular circadian clocks optimize organismal physiology to the environment by influencing the timing and coordination of metabolic processes. Host-microbe interactions are influenced by dietary quality and timing, as well as daily light/dark cycles that entrain circadian rhythms in the host. Together, the gut microbiome and the molecular circadian clock play a coordinated role in neural processing, metabolism, adipogenesis, inflammation, and disease initiation and progression. This review examines the bidirectional interactions between the circadian clock, gut microbiota, and host metabolic systems and their effects on obesity and energy homeostasis. Directions for future research and the development of therapies that leverage these systems to address metabolic disease are highlighted.
Afghanistan and the Great Powers in Regional Geopolitics, Economics and Security

Afghanistan occupies a point of convergence of great power interests in a new Great Game across a region dealing with such issues as terrorist and criminal activity, narcotics trafficking and porous borders. The great powers have also in recent years importantly converged in their trying to promote an Afghan peace process. A promising future for Afghanistan depends as well on a better-integrated region economically and substantial progress toward political reconciliation among the neighboring states. Afghanistan occupies a place in a region where rivalries play out usually to its detriment. At present, the security-driven agendas of its neighbors, particularly the enmity between India and Pakistan, strongly encumber the trans-regional movement of goods and services on which Afghanistan depends so heavily. In turn, the armed struggle in Afghanistan challenges the well being of the region. The country’s long history of instability and armed conflict threatens the region’s ability to realize its potentials for economic growth through economic connectivity and regional political cooperation. The appropriate means for resolving the Afghan conflict and regional disagreements is generally thought to be the exercise of diplomacy. Yet spoilers, domestic and foreign, have demonstrated their ability to impede negotiations with which they feel uncomfortable. Russia, China and the US, with their perceived stakes in the region and in pursuit of their own strategic objectives, have at times exacerbated the differences among the region’s states. But these powers are also in a position to encourage integration and thus further regional peace and stability. In Afghanistan, the future lies ultimately with the Afghans themselves, but the actions of the regional powers and the international community, most of all the great powers, figure prominently in the country’s economic survival and hopes for security.
RAS Nanoclusters Selectively Sort Distinct Lipid Headgroups and Acyl Chains

RAS proteins are lipid-anchored small GTPases that switch between the GTP-bound active and GDP-bound inactive states. RAS isoforms, including HRAS, NRAS and splice variants KRAS4A and KRAS4B, are some of the most frequently mutated proteins in cancer. In particular, constitutively active mutants of KRAS comprise ∼80% of all RAS oncogenic mutations and are found in 98% of pancreatic, 45% of colorectal and 31% of lung tumors. Plasma membrane (PM) is the primary location of RAS signaling in biology and pathology. Thus, a better understanding of how RAS proteins localize to and distribute on the PM is critical to better comprehend RAS biology and to develop new strategies to treat RAS pathology. In this review, we discuss recent findings on how RAS proteins sort lipids as they undergo macromolecular assembly on the PM. We also discuss how RAS/lipid nanoclusters serve as signaling platforms for the efficient recruitment of effectors and signal transduction, and how perturbing the PM biophysical properties affect the spatial distribution of RAS isoforms and their functions.
Motion, and Patient-Reported Outcomes

Objectives:Patients with irreparable rotator cuff tears (RCT) exhibit functional limitations believed to be caused by superior migration of the humerus1,2. One viable treatment is superior capsule ...
COVID-19 Raises a Health & Human Rights Imperative to Advance a UN Convention on the Rights of Older Persons (preprint)

The COVID-19 pandemic has revealed the inequitable health harms and human rights violations faced by older persons, raising a need to support healthy ageing policy as a human rights imperative. However, international human rights law has long neglected the health-related human rights of older persons. Drawing from evolving advocacy efforts to advance the rights of older persons through the United Nations (UN), tentative initial steps have been taken at the regional level, with States in the Americas codifying intersectional rights obligations underlying health through the Inter-American Convention on Protecting the Human Rights of Older Persons. These international and regional efforts provide a foundation to advance the right to health for older persons. Amid an ongoing demographic transition and an inequitable pandemic response, the prospective UN Convention on the Rights of Older Persons provides a crucial opportunity to elaborate and uphold the international legal obligations necessary to facilitate healthy ageing.