cssi/SciSciGPT-SciSciNet huggingface dataset:
A Delphi Study of RFID Applicable Business Processes and Value Chain Activities in Retail

For this research we use Delphi technique to identify the key business processes and value chain activities that are improved by RFID. Our Delphi study involves 74 experts from different domains such as consulting, retail, academia, and third party service providers. We also explored whether there is any difference in expert perceptions about RFID applicable business processes and value chain activities across different business associations.
IDEA: Interactive Display for Evolutionary Analyses

Background The availability of complete genomic sequences for hundreds of organisms promises to make obtaining genome-wide estimates of substitution rates, selective constraints and other molecular evolution variables of interest an increasingly important approach to addressing broad evolutionary questions. Two of the programs most widely used for this purpose are codeml and baseml, parts of the PAML (Phylogenetic Analysis by Maximum Likelihood) suite. A significant drawback of these programs is their lack of a graphical user interface, which can limit their user base and considerably reduce their efficiency.
Raman spectrum and lattice parameters of MgB 2 as a function of pressure

We report Raman spectra and synchrotron x-ray diffraction measurements of lattice parameters of polycrystalline ${\mathrm{MgB}}_{2}$ under hydrostatic pressure conditions up to 15 GPa. An anomalously broadened Raman band at $620{\mathrm{cm}}^{\ensuremath{-}1}$ is observed that exhibits a large linear pressure shift of its frequency. The large mode damping and Gr\"uneisen parameter indicate the vibration is highly anharmonic, broadly consistent with theoretical predictions for the ${E}_{2g}$ in-plane boron stretching mode. The results obtained may provide additional constraints on the electron-phonon coupling in the system.
MAJOR FACTORS IN THE GOVERNMENT BOND MARKET (Discussion)

IN THESE PAPERS this morning we have had three quite searching examinations of various aspects of the environment in which Treasury financing operates. My remarks have been framed largely in consideration of Mr. Piser's paper, "Major Factors and Trends in the Government Bond Market." In his presentation, Mr. Piser sets forth a concise and generally unexceptionable review of 1952 developments in the government market. Looking ahead, he makes a pointed appraisal of what are considered the alternative probabilities for 1953. He describes the 1952 bond market as one "with no outstanding trend," and continues with the statement that "the natural forces that influence the market have been working toward a closer balance." The fluctuations in bond prices are noted, but viewed as a range of "normal" magnitude in the light of the record in past years. In the 1952 market, of course, the demand for long-term funds has been heavy. A preliminary estimate might put the net increase in mortgage debt and long-term debt of corporations and state and local governments close to one-fifth greater than in 1951. In addition, during 1952, gross sales of government securities for new money (excluding savings bonds) totaled some $9 billion, double the previous year's volume. Balancing this rising demand in the market has been an increased flow of institutional investable funds. For 1953, however, I read Mr. Piser's paper as implying either a zero or negative rate of increase in net new market demands for funds. On the supply side, in contrast, an equally sharp drop in the rate of increase seems more difficult to support. The contractual nature of, and the secularly rising trend in, some major forms of liquid saving will cushion any dwindling in the rate at which net new funds are supplied. In the process of balancing these flows, there appears a reasonable possibility for a gentle change in the underlying trend of price movements in the long-term market between 1952 and 1953. One cannot discuss such tendencies apart from market expectations. It can well be argued that trends toward lower bond prices in late 1952, and toward higher bond prices in early 1953, have
A low-loss 1.8GHz monolithic thin-film piezoelectric-on-substrate filter

A 1.8 GHz thin-film piezoelectric-on-substrate (TPoS) filter with insertion loss of less than 4 dB and bandwidth of 18 MHz (50Omega termination) is presented in this paper. Such filters are alternatives to conventional ladder-type filters working in the frequency range of up to a few GHz. A monolithic TPoS filter is a coupled mode system based on a single composite resonant structure, with a thin piezoelectric layer deposited on a high acoustic velocity, low loss substrate layer. An interdigitated top electrode structure is used that eliminates the spurious modes and provides a mechanism for adjusting the bandwidth.
Robust adaptive flow control in high speed telecommunication networks

We consider a single controlled traffic source, sharing a bottleneck node with other (higher priority) sources, whose traffic is modeled by an ARMA process. The controlled source adapts dynamically its transmission rate to the remaining available bandwidth. We focus in this paper on the case when the ARMA parameters are unknown. We use an H/sup /spl infin// approach, and design a controller which combines identification (of the ARMA parameters) with the control in a novel way.
Amorphous-Silicon Thin-Film Transistors Fabricated at 300 $^{\circ}\hbox{C}$ on a Free-Standing Foil Substrate of Clear Plastic

We have made hydrogenated amorphous-silicon thin-film transistors (TFTs) at a process temperature of 300degC on free-standing clear-plastic foil substrates. The key to the achievement of flat and smooth samples was to design the mechanical stresses in the substrate passivation and transistor layers, allowing us to obtain functional transistors over the entire active surface. Back-channel-passivated TFTs made at 300 degC on glass substrates and plastic substrates have identical electrical characteristics and gate-bias-stress stability. These results suggest that free-standing clear-plastic foil can replace display glass as a substrate from the points of process temperature, substrate and device integrity, and TFT performance and stability.
Vincristine and vinblastine lower plasma cholesterol concentrations in rhesus monkeys.

3–4 days after a single clinical dose of vincristine or vinblastine in rhesus monkeys there was a marked decrease in plasma low-density lipoprotein cholesterol concentrations. There was also a concomittant increase in plasma triacylglycerol concentrations. Plasma lipid levels returned to normal concentrations within 7–10 days after injection. Plasma high-density lipoprotein cholesterol concentrations were unaltered by the drugs. Electron micrographs of the hepatocytes from monkeys treated with vincristine or vinblastine showed an accumulation of glycogen particles and proliferation of smooth endoplasmic reticulum, which was accompanied by an increase in the number of lipoprotein-containing vesicles. These results indicate that vincristine and vinblastine alter plasma cholesterol and triacylglycerol concentrations in part by interfering with hepatic lipid and lipoprotein metabolism. These studies further suggest the possibility that other less cytotoxic alkaloids from Catharanthus species with clinically useful hypocholesterolemic activity may be discovered.
Problem and Pathological Gambling among College Students.

This chapter examines problem and pathological gambling among college students and reports on prevalence rate, risk and protective factors, prevention and intervention, and recommendations for college student personnel and other university administrators.
The proximal signaling network of the BCR-ABL1 oncogene shows a modular organization

BCR-ABL1 is a fusion tyrosine kinase, which causes multiple types of leukemia. We used an integrated proteomic approach that includes label-free quantitative protein complex and phosphorylation profiling by mass spectrometry to systematically characterize the proximal signaling network of this oncogenic kinase. The proximal BCR-ABL1 signaling network shows a modular and layered organization with an inner core of three leukemia transformation-relevant adaptor protein complexes (Grb2/Gab2/Shc1 complex, CrkI complex and Dok1/ Dok2 complex). We introduced an ‘interaction directionality’ analysis, which annotates static protein networks with information on the directionality of phosphorylationdependent interactions. In this analysis, the observed network structure was consistent with a step-wise phosphorylation-dependent assembly of the Grb2/Gab2/ Shc1 and the Dok1/Dok2 complexes on the BCR-ABL1 core. The CrkI complex demonstrated a different directionality, which supports a candidate assembly on the Nedd9 (Hef1, CasL) scaffold. As adaptor protein family members can compensate for each other in leukemic transformation, we compared members of the Dok and Crk protein families and found both overlapping and differential binding patterns. We identified an additional level of regulation for the CrkII protein via binding to 14-3-3 proteins, which was independent from its inhibitory phosphorylation. We also identified novel components of the inner core complexes, including the kinases Pragmin (Sgk223) and Lrrk1 (Lrrk2 paralog). Pragmin was found as a component of the CrkI complex and is a potential link between BCR-ABL1/CrkI and RhoA signaling. Lrrk1 is an unusual kinase with a GTPase domain. We detected Lrrk1 as a component of the Grb2/Gab2/Shc1 complex and found that it functionally interacts with the regulator of small GTPases Arap1 (Centd2) and possibly participates in the mitogenactivated protein kinase response to cellular stresses. This modular and phosphorylation-driven interaction network provides a framework for the integration of pleiotropic signaling effects of BCR-ABL1 toward leukemic transformation.
Stratiform Precipitation, Vertical Heating Profiles, and the Madden Julian Oscillation

Abstract The observed profile of heating through the troposphere in the Madden–Julian oscillation (MJO) is found to be very top heavy: more so than seasonal-mean heating and systematically more so than all of the seven models for which intraseasonal heating anomaly profiles have been published. Consistently, the Tropical Rainfall Measuring Mission (TRMM) precipitation radar shows that stratiform precipitation (known to heat the upper troposphere and cool the lower troposphere) contributes more to intraseasonal rainfall variations than it does to seasonal-mean rainfall. Stratiform rainfall anomalies lag convective rainfall anomalies by a few days. Reasons for this lag apparently include increased wind shear and middle–upper tropospheric humidity, which also lag convective (and total) rainfall by a few days. A distinct rearward tilt is seen in anomalous heating time–height sections, in both the strong December 1992 MJO event observed by the Tropical Ocean Global Atmosphere Coupled Ocean–Atmosphere Response ...
Integrating Declarative Programming and Probabilistic Planning for Robots

Mobile robots deployed in complex real-world domains typically find it difficult to process all sensor inputs or operate without substantial domain knowledge. At the same time, humans may not have the time and expertise to provide elaborate and accurate knowledge or feedback. The architecture described in this paper combines declarative programming and probabilistic sequential decision-making to address these challenges. Specifically, Answer Set Programming (ASP), a declarative programming paradigm, is combined with hierarchical partially observable Markov decision processes (POMDPs), enabling robots to: (a) represent and reason with incomplete domain knowledge, revising existing knowledge using information extracted from sensor inputs; (b) probabilistically model the uncertainty in sensor input processing and navigation; and (c) use domain knowledge to revise probabilistic beliefs, exploiting positive and negative observations to identify situations in which the assigned task can no longer be pursued. All algorithms are evaluated in simulation and on mobile robots locating target objects in indoor domains.
The Organizational Structures at the Grassroots Level: Theoretical Overview

This Article presents a range of definitions and descriptions from recent sources and elaborates on the concept of decentralization, again drawn from secondary sources. Thus it elaborates on decentralization in the context of alternative services delivery an area of increasing application world-wide and presents a preliminary assessment of the strengths and weaknesses of the definitions. It elaborates on selected aspects of decentralization. Several different ways of classifying forms of decentralization have been promoted over the past few decades by those making a clear distinction between centralization and decentralization. What is common to these classification systems is that they recognize the need for a definition that is grounded on more than legal concerns. Six forms of approaches can be identified in the literature.
SONIC FATIGUE DESIGN AND NONLINEAR PANEL RESPONSE TO FLIGHT NONWHITE PRESSURE FLUCTUATIONS

In stochastic structural dynamics, majority of the analyses have dealt with linear structures under stationary Gaussian and band-limited white-noise excitation (WN). Recorded B-1B flight acoustic pressure fluctuations have shown: (i) the high levels of acoustic excitation that may drive the surface panels to nonlinear large deflection response, and (ii) the nonwhite power spectral density (PSD) characteristic which may affect panel response and fatigue life. This paper presents the nonlinear response and fatigue life estimation of isotropic and composite panels subjected to nonwhite acoustic excitation. An efficient finite element time domain modal formulation is employed to determine the panel response, and the Palmgren-Miner cumulative damage theory and the rainflow counting cycles method are used to estimate the panel fatigue life. To assess the effects of nonwhite PSD characteristic, an equivalent band-limited white noise excitation (EWN), which has the same acoustic power within the bandwidth as the B-1B flight data, is simulated. Nonlinear response and fatigue life are determined for the identical panel subjected to EWN. Results showed that the actual flight data with nonwhite PSD give higher stress characteristics and shorter fatigue life than the corresponding EWN.
Implementation of standardized dosing units for i.v. medications

Purpose The implementation of standardized dosing units for six i.v. medications at an academic medical center is described. Summary During the implementation of an electronic health record system at an academic medical center, it was noticed that providers could order some i.v. medications in multiple dosing units, including epinephrine, isoproterenol, midazolam, nitroglycerin, norepinephrine, and phenylephrine. Possible options to standardize i.v. medications along with their pros and cons were presented for discussion to key providers in all of the intensive care units. Once the providers agreed on a solution, the information was presented to the pharmacy and therapeutics committee for final approval. A nursing education plan was created and administered before the standardization of dosing units was implemented. A nursing survey was conducted before and after implementation of dosing-unit standardization to determine the effectiveness of nursing education on compliance with the standardization of the dosing units for the listed medications. The survey was designed to evaluate, when given a choice, what dosing units nurses would use to administer epinephrine, isoproterenol, midazolam, nitroglycerin, norepinephrine, and phenylephrine. The decision was made by the key providers to use weight-based dosing—micrograms per kilograms per minute—to allow for consistency of use of these medications for pediatric and adult patients. Nursing education was completed to ensure that nurses were aware of how to safely administer these medications using the new dosing units. Conclusion Dosing-unit standardization for dose-adjustable i.v. infusions can provide improved consistency and decrease the potential for dosing errors when administering epinephrine, isoproterenol, midazolam, nitroglycerin, norepinephrine, and phenylephrine.
A Nondiapausing Strain of Pink Bollworm from Southern India

A strain of the pink bollworm, Pectinophora gossypiella (Saunders), collected near Mandya (Mysore Province) in southern India (12°N, 77°E) was tested in the laboratory for evidence of ability to diapause. The strain failed to undergo diapause when exposed to environmental conditions that induced 94–98% diapause in a native (Arizona) strain. When the India strain was crossed with the Arizona strain, the F1 hybrid showed approximately 50% reduction in diapause response. It was concluded that the India strain lacks the capability for diapause and will be useful for studying the genetics of diapause in this species.
ENVIRONMENTAL REVIEWS AND CASE STUDIES: “Environmental Protection Bureau, 2.0”: China's Environmental Courts as Enforcement Institutions

This article examines the impact of environmental courts on environmental enforcement in China. Situating the environmental courts within the long arcs of environmental lawmaking and environmental enforcement in China, where a fractured bureaucratic state increasingly drives patterns of experimentation, this article argues that Chinese environmental courts are best understood as “Environmental Protection Bureaus 2.0.” That is, rather than courts in the traditional legal understanding of the term, it is more productive to think of China's environmental courts as another bureaucratic actor. The courts' entrance into an increasingly crowded environmental enforcement hierarchy increases competition and collaboration with traditional and newly created enforcement institutions. This in turn results in institutional feedback that could heighten environmental protection outcomes. The article concludes by briefly examining what these dynamics mean for environmental federalism in China.Environmental Practice 15:441–461 (2013)
Fungal septal abscess complicating maxillary sinus fungus balls in an immunocompetent host.

Background Fungal infections of the nasal cavity can be destructive entities that are typically seen in immunocompromised hosts. We present a case of a localized fungal abscess of the nasal septum in an immunocompetent host after endoscopic treatment of maxillary sinus fungus balls. Method A 51-year-old woman with a history of asthma and recent treatment with oral steroids presented with bilateral maxillary sinus mycetomas. She underwent endoscopic sinus surgery. The postoperative course was complicated by an asthma flare, which required oral steroids. The patient returned with nasal obstruction, and results of a physical examination were consistent with a nasal septal abscess. Drainage was attempted, and cultures showed fungal elements. The abscess reaccumulated, and the patient was referred to our institution. Operative drainage was performed with placement of a catheter in the septal abscess cavity. Forty-eight hours of amphotericin irrigations were performed through this site. The patient was started on oral antifungal therapy. Results of an immune workup, including testing for human immunodeficiency virus and assessing immunoglobulin levels, were negative. Final fungal cultures grew Scedosporium apiospermum sensitive to voriconazole. The patient completed therapy without further recurrence. Follow-up at 6 months demonstrated no further recurrence of her fungal septal infection. Conclusion Sinonasal fungal infections rarely occur in immunocompetent hosts. The septum may have been seeded during the endoscopic sinus surgery. The use of oral steroids may have been a risk factor for the development of an aggressive nasal septal fungal abscess in this patient. This is the first reported case of a nasal septal abscess in an otherwise immunocompetent host with S. apiospermum.
Dysplasia discrimination in intestinal-type neoplasia of the esophagus and colon via digital image analysis

Determining gastrointestinal tract dysplasia level is clinically important but can be difficult, and given this challenge, we investigated colonic and esophageal dysplastic progression using digital image analysis (IA). Whole slide images were obtained for colonic normal mucosa (NCM), hyperplastic polyps (HP), conventional tubular adenomas (TA), and adenomas with high-grade dysplasia (HGD), and esophageal intestinal metaplasia negative for dysplasia (IM), indefinite for dysplasia (IFD), low-grade dysplasia (LGD), and HGD. Characteristic nuclei were circumscribed, and parameters discriminating groups included nuclear circumference (μm), area (μm2), and 15 positive pixel count (PPC) algorithm IA measurements. In colon polyps and esophageal lesions, average nuclear area and circumference ranged 30–108.6 μm2 and 27.5–48.9 μm, respectively. Differences for average nuclear area and circumference met statistical significance (p < 0.05) between diagnostic groups in the esophagus and colon, except for IM versus IFD nuclear area. Pixel intensity (brightness) separated lesions within both groups with statistical significance except for colonic TAs versus HPs and esophageal LGD versus IM. HGD nuclei in both groups demonstrated more pixel staining heterogeneity than other lesions. Hierarchical clustering and principal component analysis demonstrated that lesions with similar diagnoses tended to cluster together on a low- to high-grade spectrum. Our results confirm that quantitative IA is an effective adjunct reflecting dysplasia in colon polyps and Barrett esophagus lesions. Nuclear area, circumference, and PPC algorithm findings distinguished lesions in a statistically significant manner. This suggests utility for future studies on similar methods, which may provide an adjunctive ancillary technique for pathologists and enhance patient care.
Effects of Inequity on Human Free-Operant Cooperative Responding: A Validation Study

The effect of disparities in reinforcement frequency on human free-operant cooperative responding was examined. Points exchangeable for money maintained responding. Two schedule components alternated during a session. A random interval (Rl) 60-s schedule of point additions was in effect during the first component and a concurrent RI 60-s RI 60-s schedule was in effect during the second component. Subjects were instructed that the second component was initiated by another subject and that they had the option of earning points by working with, or independently of, the other subject. Independent responses earned points added to a counter marked “YOUR EARNINGS.” Cooperative responses earned points added simultaneously to a counter marked “YOUR EARNINGS” and “OTHERS EARNINGS.” Disparities of reinforcement were produced during the first component by increasing the frequency of point additions to either the subject’s or the fictitious other person’s counter. Disparities benefiting the fictitious other subject reduced cooperative responding, decreased independent responding, and had no effect on nonsocial responding during the first component. Disparities benefiting the subject increased cooperative responding in one subject.
Investigating dominant characteristics of fires across the Amazon during 2005–2014 through satellite data synthesis of combustion signatures

Estimates of fire emissions remain uncertain due to limited constraints on the variations in fire characteristics. Here we demonstrate the utility of space-based observations of smoke constituents in addressing this limitation. We introduce a satellite-derived smoke index (SI) as an indicator of the dominant phase of large-scale fires. This index is calculated as the ratio of the geometric mean of observed fractional enhancements (due to fire) in carbon monoxide and aerosol optical depth to that of nitrogen dioxide. We assess the usefulness of this index on fires in the Amazon. We analyze the seasonal, regional, and interannual joint distribution of SI and fire radiative power (FRP) in relation to fire hotspots, land cover, drought severity index, and deforestation rate estimates. We also compare this index with an analogous quantity derived from field data or emission inventories. Our results show that SI changes from low (more flaming) to high (more smoldering) during the course of a fire season, which is consistent with the changes in observed maximum FRPs from high to low. We also find that flaming combustion is more dominant in areas where deforestation fires dominate, while smoldering combustion has a larger influence during drought years when understory fires are more likely enhanced. Lastly, we find that the spatiotemporal variation in SI is inconsistent with current emission inventories. Although we recognize some limitations of this approach, our results point to the utility of SI as a proxy for overall combustion efficiency in the parameterization of fire emission models.
Association of decline in serum Ca19-9 after neoadjuvant therapy with improved survival among borderline resectable pancreatic cancer patients.

e15082 Background: Serum Ca19-9 (19-9) decline in response to therapy has been associated with an increased overall survival in metastatic pancreatic cancer patients (pts). However, the prognostic ...
Toward individualized treatment for substance abuse.

Clinical observation and research discovery each can give rise to treatments that prove effective in clinical trials and, accordingly, are considered evidence-based. For example, motivational interviewing draws on, and addresses, clinicians’ recognition of patient ambivalence, and contingency management emerged from research on the effects of rewards on human behavior. Whether they originate in the clinic or the research setting, evidence-based treatments provide clinicians with tools to treat patients more effectively while still treating each as a unique individual. Thus, motivational interviewing, by moving clients past ambivalence, clears the way to addressing other issues that are particular to the individual. Contingency management, similarly, can increase clinicians’ ability to address clients’ individual issues by motivating attendance in sessions and other desirable behaviors. The future of substance abuse treatment is the development of an increasing array of evidence-based treatments that clinicians will use to address patients’ varied strengths, needs, and circumstances. We have already begun to see the emergence of evidence-based treatments for patients with certain co-dependencies and co-occurring disorders. Research reviewed in this issue of Addiction Science & Clinical Practice suggests that interventions might be developed for patients in specific stages of addiction, with different types and degrees of cognitive impairment, or with particular genotypes. Far from reducing the role of clinicians and the importance of the therapeutic relationship, evidence-based treatments rely heavily on clinical skills and empathy. Increasingly, clinicians will need to be familiar with the variety of available evidence-based treatments, to identify the right one—or combination or sequence—for each patient and to administer a range of assessments and interventions with fidelity. For substance abuse clinicians, the tools, the challenges, and the potential for success increase in concert.
What Good are Partial Autopsies

Partial autopsies are performed for a variety of reasons. They are regarded as safer in higher risk cases involving blood-borne pathogens. They can be completed more quickly - the examination of th...
KNOWLEDGE DEVELOPMENT FOR AGE-FRIENDLY COMMUNITY INITIATIVES

AbstractThis paper will provide an introduction to “age-friendly” as an emerging international field of research, policy, and practice. The presenters will provide a history of the age-friendly movement, including the World Health Organization’s initiative and how age-friendly efforts have emerged across diverse national contexts over the past decade. The presenters will then describe knowledge development concerning age-friendly community initiatives, noting that much of what has been written in this area has been published in the “gray” literature. While peer-reviewed publications on age-friendly efforts are growing in number, many remain descriptive or theoretical. Based on a review of the literature, this paper will identify opportunities for researchers to employ both qualitative and quantitative research methodologies to deepen systematic knowledge building concerning age-friendly community initiatives. The authors will describe how such knowledge development has the potential to strengthen age-friendly policies and practices, while also making meaningful advances to gerontological research more broadly.
Myoglobin Saturation and Calculated PO2 in Single Cells of Resting Gracilis Muscles

Use of myoglobin (Mb) as an indicator of intracellular PO2 has been dormant for half a century, chiefly because of difficulty in differentiating Mb from hemoglobin (Hb) when both are illuminated. We recently devised a microspectrophotometer with which light can be collected exclusively from either Hb or Mb. Spatial resolution is 2–5 μ. Since freezing arrests chemical reaction, saturation measurements on a large cell population can be interpreted as though all the measurements had been made simultaneously. In this way the purely spatial uniformity of O2 delivery can be evaluated. Measurements can be made at several loci within one cell, at various loci in a cell cluster, or in cells selected at random from grossly different regions of the muscle. The method offers the further advantage that the contribution of local capillary recruitment to O2 delivery can be evaluated.
Evaluating the determinants of sugary beverage consumption among overweight and obese adults: An application of the integrative model of behavioural prediction

Objective:The objective of this study was to evaluate the determinants of sugary drink consumption among overweight and obese adults attempting to lose weight using the Integrative Model of Behavioural Prediction (IMB).Design:Cross-sectional design.Method:Determinants of behavioural intentions (attitudes, perceived norms and perceived behavioural control [PBC]) and sugary drink consumption (intentions, skills/abilities, environment and PBC) were evaluated using data collected at a weight loss clinic in a southwestern US city (n = 338). Determinants of attitudes, injunctive norms, descriptive norms and PBC were evaluated using salient beliefs, which were derived from an elicitation study.Results:Using structural equation modelling, two separate models were evaluated. Both models had good fit (combined model – Comparative Fit Index [CFI] = .970, Tucker–Lewis Index [TLI] = .921, Root Mean Square Error of Approximation [RMSEA] = .062; expanded model – CFI = .966, TLI = .911, RMSEA = .060) and accounted for a ...
Entr’acte at the Theatre: Marriage, Money, and Feeling in Love Among the Artists

In the middle of Love Among the Artists—in an interval or “entr’acte” beginning in a theatre box before a pair of marriages occur and the prospects of other romantic attachments are dashed—Shaw provides a kind of precis not just of this novel, but of the larger material psychology that informs his fiction and much of his later work as well. Given the fact that this is the only one of Shaw’s novels lacking any introductory commentary—for, although not preceded by a substantial preface, even An Unsocial Socialist has a brief “Foreword”—my reading of this scene at the theatre and the one immediately following it might be considered, much as Shaw’s prefaces are, as a distillation of its themes. Moreover, after the lengthy treatment of Immaturity and The Irrational Knot in the previous chapter and the sustained examination of blushing and feeling in Cashel Byron’s Profession that follows, this brief essay might also serve, like an interval at the theatre, as a salutary respite from the lengthy interpretive action that surrounds it.
Ajulemic acid: potential treatment for chronic inflammation

Ajulemic acid (AJA, CT-3, IP-751, JBT-101, anabasum) is a first-in-class, synthetic, orally active, cannabinoid-derived drug that preferentially binds to the CB2 receptor and is nonpsychoactive. In preclinical studies, and in Phase 1 and 2 clinical trials, AJA showed a favorable safety, tolerability, and pharmacokinetic profile. It also demonstrated significant efficacy in preclinical models of inflammation and fibrosis. It suppresses tissue scarring and stimulates endogenous eicosanoids that resolve chronic inflammation and fibrosis without causing immunosuppression. AJA is currently being developed for use in 4 separate but related indications including systemic sclerosis (SSc), cystic fibrosis, dermatomyositis (DM), and systemic lupus erythematosus. Phase 2 clinical trials in the first 3 targets demonstrated that it is safe, is a potential treatment for these orphan diseases and appears to be a potent inflammation-resolving drug with a unique mechanism of action, distinct from the nonsteroidal anti-inflammatory drug (NSAID), and will be useful for treating a wide range of chronic inflammatory diseases. It may be considered to be a disease-modifying drug unlike most NSAIDs that only provide symptomatic relief. AJA is currently being evaluated in 24-month open-label extension studies in SSc and in skin-predominant DM. A Phase 3 multicenter trial to demonstrate safety and efficacy in SSc has recently been initiated.
Hyperventilation syndrome: a diagnosis begging for recognition.

Refer to: Magarian G J, Middaugh DA, Linz DH: Hyperventilation syndrome: A diagnosis begging for recognition (Topics in Primary Care Medicine). West J Med 1983 May; 138:733-736. From Ambulatory Care and Medical Services, Veterans Administration Medical Center, and the Division of General Medicine, Department of Medicine, Oregon Health Sciences University, Portland. Supported in part by HEW grant No. 1-028-PE10051-02. Reprint requests to Gregory J. Magarian, MD, Ambulatory Care Service (llC), Veterans Administration Medical Center, Portland, OR 97207.
Design Issues for a Light Ion Beam LMF Driver

The U.S. Department of Energy is conducting a preliminary study of a Laboratory Microfusion Facility (LMF). A major goal of the LMF is the development of high-gain ICF targets in a laboratory envir...
A Strategy for Geomedical Surveillance Using the Hawkeye Knowledge Discovery System

An approach for the coordination of epidemiologic surveillance within local hospitals as well as across multiple hospital sites, which use the Hawkeye knowledge discovery system, is presented. It is proposed that this coordination be supported by agent-based collaboration technology. This framework meets important criteria recommended by ProMED such as a strongly horizontal decentralized structure.
SEIZURES | Autonomic Consequences of Seizures, Including Sudden Unexpected Death in Epilepsy

Seizure activity that spreads through limbic and neocortical regions also spreads into hypothalamic and medullary brain regions, and finally into the periphery via the autonomic nervous system. The autonomic consequences of seizures include cardiovascular effects that can be life-threatening. Studies of epilepsy patients and various animal models have contributed to a deeper understanding of the autonomic impact of seizure activity, but many features of autonomic involvement, including the mechanisms for sudden unexpected death in epilepsy, are still poorly understood. As our understanding grows, specific autonomic monitoring techniques may become prevalent tools for setting an alert system in seizure patients and for defining patients’ risk for severe cardiovascular consequences.
Can A Low Cost Sensing System Be Exploited For High Precision Machining

Abstract The aim of the present study is the assessment of the integration of a low cost optical measurement device into a high-precision machine tool for micro manufacturing applications. The measurement system can be effectively integrated into the working volume of different types of machines allowing both tool and workpiece measurements and avoiding its disassembly from the machine stage for off-line measurements and, consequently, reference losses. The fast measurements of tool and workpiece during the machining contribute to increase the accuracy and reduce the overall machining-measurement iterations. The assessment is achieved by a test case where a low cost USB microscope is applied to a micro-EDM machine. The low cost device has been applied for tool electrode measurements and tool wear evaluation after an accuracy enhanced calibration procedure and high performance image processing algorithms, which effectively reduce the lack of the hardware performance. The measurement performance gives a feedback on the deviations of the machined features from nominal geometry and allows their compensations by an adequate machining strategy.
Impact of road grade on real driving emissions from two Euro 5 diesel vehicles

Abstract On-road real driving emissions (RDE) testing was used to study the effects of many parameters not taken into account by laboratory testing but which can greatly influence vehicle pollutant emissions. Among these, road grade plays a key role. This paper investigates the effects of positive and negative road grades on the exhaust emissions of two Euro 5 diesel vehicles. Both vehicles were tested in the laboratory on the chassis dynamometer and on the road along a mixed route in Naples (Italy). The circuit includes urban, extra-urban and motorway driving in order to comply with Euro 6 RDE requirements. Laboratory testing aimed to assess emissions during current type approval driving cycles; on-road tests using portable analysers were used to determine real emissions as a function of road gradient. Vehicle Specific Power (VSP) analysis revealed that with respect to positive road grades, negative ones explain a higher share of total VSP. For −4% to +5% road gradients, the percentage variation of carbon dioxide emissions is linearly correlated with variations in slope. The same correlation for nitrogen oxides is vehicle dependent and well explained by a second-order polynomial function.
Shrinking local autonomy: corporate coalitions and the subnational state

Using focus groups and government finance data, we explore three areas of US state rescaling at the subnational level: revenue tools, expenditure responsibilities and policy authority. Expenditure responsibilities, especially social welfare, have been devolved to the subnational level, while local revenue tools and policy authority are preempted. This decoupling of responsibility and power is cracking the foundations of fiscal federalism. At the behest of corporate-legislative coalitions, subnational state governments are shrinking local capacity and authority to govern. This is not state shrinkage; it is a fundamental reshaping of the subnational state to the detriment of democracy and the social contract.
Author Correction: Epigenetic regulation in psychiatric disorders.

In part c of Figure 1 in this article, the orientation of the tail of histone 3 with respect to the core region of this molecule was incorrect, and the amino acid residue K79 should not have been depicted in the tail. The corrected figure is shown below. The authors and editors thank T. Brown, R. Lober and C. Waker for bringing this error to our attention. Note that the present affiliation of the corresponding author and their current email address have been added to the correction notice.
Evaluating Measures of Pausing for Second Language Fluency Research

Dans les ecrits sur la fluidite en L2, la meilleure facon de definir les pauses de maniere operationnelle et de determiner quel est le lien entre les differentes mesures des pauses et la maitrise d...
The Faint End of the Luminosity Function of Galaxies in Hickson Groups

We study the luminosity function of galaxies in Hickson groups using our recent redshift survey of galaxies in and around 17 of these groups. We find that the galaxies in these regions have a luminosity function with M∗ = −19.5 + 5logh, and α = −1.0, where M∗ and α are the usual parameters in the standard Schechter form of the luminosity function, and the magnitudes are measured in the B band. The formal 95% confidence intervals for M∗ and α range from (-19.3,-0.8), to (-19.7,-1.2) and are highly correlated as is usual for these fits. This luminosity function for galaxies in our Hickson group sample is very similar from that found in large surveys covering a range of environments. These values are also consistent with our earlier estimates based on a photometric analysis with statistical background correction, and do not support previous suggestions of an underabundance of intrinsically faint galaxies in compact groups. We confirm our earlier finding that the fainter galaxies are more diffusely distributed within individual groups than the brighter ones. This can be interpreted either as evidence for mass segregation within the groups or as the result of the selection procedure for Hickson groups. Subject headings: galaxies: clusters – galaxies: interactions – galaxies: luminosity function – galaxies: statistics Hubble Fellow e-mail:zepf@astro.yale.edu
Postoperative penile prosthesis pain: is it worse in diabetic patients?

Inflatable penile prosthesis (IPP) surgery is an effective, safe and satisfactory treatment option for medication-refractory erectile dysfunction. Postoperative complications include infection, mechanical failure, erosion, and pain. Current literature suggests the need for a better approach to postoperative pain management after IPP surgery. Clinical studies have demonstrated that postoperative pain is different in diabetic patients. We sought to determine if there is a difference in pain after IPP placement in diabetics. This is a single-institution retrospective review. The main outcome measure was the number of 30-day postoperative visits for pain. The secondary outcome included differences in how pain was managed. The top HbA1c quartile was compared with the other HbA1c quartiles. Diabetes was present in 92 (54.4%) patients and 96% of these had HbA1c > 8. Significant postoperative pain was more common in patients with HbA1c > 8 (41% vs 13%, p = 0.047) and resulted in more unplanned visits (27% vs 11%, p = 0.042). Patients with HbA1c > 8 with significant postoperative pain were more likely to be managed with opioids and gabapentin (30% vs 14%, p = 0.05). There were no statistical differences in age between diabetics and non-diabetics (mean 59 vs 61, p = 0.193). Hispanic and African-American patients represented 87% of the poorly controlled diabetics compared with only 13% of white patients (p 8 was predictive of an unplanned visit for pain with an OR of 2.83 (p = 0.04). Significant pain after IPP surgery was higher in diabetics with HbA1c > 8, which resulted in more unplanned 30-day postoperative visits. Patients with significant postoperative pain were managed with a combination of opioids and gabapentin. Future studies are required to optimize pain management in diabetics following IPP placement.
Photolithography Solution That Overcomes Significant Die Placement Error For Advanced Packaging

The requirement for smaller features and tighter die in advanced wafer level packaging (WLP) and advanced panel level packaging (PLP) makes it essential to develop more capable lithography systems. Nowadays, the requirements for advanced packaging systems with high yield goes beyond the simple inherent lens overlay, more advanced features, such as magnification (mag) and rotation(theta) correction is needed for the mismatch between the feature (or die) position/size on substrate and the reticle pattern. This paper describes the newly developed site-by-site mag and theta correction solution by adjusting the reticle chuck position in a 2X reduction photolithography system. This technology actively mitigates symmetric mag errors within a job for up to +/-400ppm, and theta errors up to +/-1.65mrad. Experimental results in this work prove that site by site mag and theta correction worked on the wafer. What is more compelling is that there is no throughput penalty to enable this capability.
Assessing coastal carbon variability in two Delaware tidal marshes

Coastal wetlands provide numerous ecosystem services, including the ability to sequester and store carbon. Recent initiatives, such as the U.S. Climate Alliance’s National Working Lands Challenge, have sought to better understand and quantify this ‘blue carbon’ storage as a land management approach to maintain, or potentially offset, atmospheric carbon emissions. To build on this effort locally, loss on ignition and elemental analyses were used to assess sediment organic matter, dry bulk density, and carbon density variability within the root zone of a mesohaline and oligohaline tidal marsh in Delaware. Additionally, we assessed sediment carbon variability at depth greater than one meter and quantified the black carbon fraction in the mesohaline tidal marsh. Organic matter concentrations ranged between 11.85 ± 1.19% and 23.12 ± 6.15% and sediment carbon density ranged from 0.03 ± 0.01 g cm−3 to 0.06 ± 0.02 g cm−3 with both found to significantly differ between the mesohaline and oligohaline tidal marsh systems. Significant differences between dominant vegetation types were also found. We used these data to further estimate and valuate the carbon stock at the mesohaline tidal marsh to be 350 ± 310 metric tons of soil carbon accumulation per year with a social carbon value of $40,000 ± $35,000. This work improves our knowledge of Delaware-specific carbon stocks, and it may further facilitate broad estimates of carbon storage in under-sampled areas, and thereby enable better quantification of economic and natural benefits of tidal wetland systems by land managers.
Bio-LSTM: A Biomechanically Inspired Recurrent Neural Network for 3D Pedestrian Pose and Gait Prediction

In applications such as autonomous driving, it is important to understand, infer, and anticipate the intention and future behavior of pedestrians. This ability allows vehicles to avoid collisions and improve ride safety and quality. This paper proposes a biomechanically inspired recurrent neural network (Bio-LSTM) that can predict the location and 3D articulated body pose of pedestrians in a global coordinate frame, given 3D poses and locations estimated in prior frames with inaccuracy. The proposed network is able to predict poses and global locations for multiple pedestrians simultaneously, for pedestrians up to 45 meters from the cameras (urban intersection scale). The outputs of the proposed network are full-body 3D meshes represented in Skinned Multi-Person Linear (SMPL) model parameters. The proposed approach relies on a novel objective function that incorporates the periodicity of human walking (gait), the mirror symmetry of the human body, and the change of ground reaction forces in a human gait cycle. This paper presents prediction results on the PedX dataset, a large-scale, in-the-wild data set collected at real urban intersections with heavy pedestrian traffic. Results show that the proposed network can successfully learn the characteristics of pedestrian gait and produce accurate and consistent 3D pose predictions.