cssi/SciSciGPT-SciSciNet huggingface dataset:
Optimization of Device Deairing and Airless Connection Techniques for Cleveland Clinic Continuous-Flow Artificial Heart

Purpose Prevention of air introduction during mechanical circulatory support device implant is critical for a successful outcome. A substantial amount of air may be introduced into the circulation during pump to outflow port connection, which may become detrimental for optimal pump function and long-term survival. In this study, we evaluated techniques of seamless, airless connection of double-ended centrifugal pump (continuous-flow total artificial heart [CFTAH]) in vivo. Methods The airless CFTAH connection techniques were evaluated in acute in vivo (n=2) CFTAH implants (Jersey calves, weight: 77.8 and 80.8 kg). Techniques consisted of pump priming with normal saline (Fig. 1 A) and application of specifically designed connection sleeve (Fig 1B). The silicone sleeve (0.3-0.5 mm thick) was prototyped using multilayer dip-coating technique over a 3D-printed mandrel. A suture line was added along the long axis, to enable easy removal. Deairing sleeve was pre-placed on each outflow port (conduit) and proximal port (port) ends (Fig.1 C). The present air was evacuated upward from an open line. The conduit and pump ports were connected within the sleeve (Fig.1 D), with air being fully excluded from circuit. The CFTAH was started at the minimum speed (2,200 rpm) after connection. Results The CFTAH pump were successfully primed with saline prior to implant to remove entrapped air. The completely seamless pump connection and exclusion of air from pump and outflow grafts has been found feasible. There were no clinical signs of air embolism in the pulmonary or systemic circulation observed during the experiment. Conclusion The seamless connection of CFTAH to outflow grafts using specifically designed connection sleeve and its easy removal was demonstrated to be feasible. Device development is ongoing and will aim to address optimal geometry, size and material selection.
Cotton Fiber-Based Sorbents for Treating Crude Oil Spills

Wood and plant fibers have been studied as natural sorbent materials for treating aquatic oil spills; however, the effectiveness of these materials is limited by their tendency to absorb water as w...
Integrating Advanced Practice Providers into value based care strategies: One organization's journey to achieve success through interprofessional collaboration

Abstract As the landscape of healthcare is shifting from volume-based to value-based practice, organizations are challenged to develop models that promote such changes with current resources while enriching the patient experience. A critical component to be successful, is utilizing an interprofessional team approach. An urban academic pediatric hospital developed such strategies by enhancing the use of Advanced Practice Providers (APPs) to optimize care. Through a series of tactics beginning with the strategic plan, results included an increase in volume, APP productivity, and enhanced satisfaction scores for both providers/patients, and an increase in access to pediatric specialty care.
Wettability alteration by Smart Water multi-ion exchange in carbonates: A molecular dynamics simulation study

Abstract Smart Water ions (Ca2+, Mg2+, and SO42−) have been found to alter the wettability of oil-wet calcite surfaces, however, the widely proposed multi-ion exchange mechanism has never been understood on a molecular scale. In this work, a new model calcite surface with steps and locally charged sites was developed, and its properties were studied by quantum chemical calculations and molecular dynamics simulations to investigate the origin of the oil-wetness and its reversal by the Smart Water ions at temperatures ranging from 300 to 400 K. The simulation results using the proposed surface model are consistent with experimental results reported in the literature, including the Smart Water ions acting as the potential determining ions, and the oil carboxylate adsorption causing oil-wetness. The wettability alteration involves initial surface binding of Ca2+, which facilitates adsorption of SO42−. The latter enables the detachment of the Ca2+-carboxylate complexes at elevated temperatures (>350 K) where the ionic hydration shells are weakened as suggested by the increased interaction energy from less than −100 to over −400 kJ/mol between Ca2+ and SO42−, rationalizing the observed temperature dependence of the Smart Water effect. Overall, the presented simulations with the newly developed model calcite surface provide important new insights into wettability alteration effect of Smart Water ions, which has important implications for the optimization of the injection brines for enhanced oil recovery.
Mechanisms and inhibitors of nicotinamide N-methyltransferase

Nicotinamide N-methyltransferase (NNMT) plays an important role in diverse biological processes by regulating methylation potential and the degradation of nicotinamide. Meanwhile, the aberrant expression of NNMT has been implicated in multiple cancers, metabolic and liver diseases. Therefore, there has been an emerging interest in assessing NNMT as a potential therapeutic target and discovering NNMT inhibitors over the past 5 years. Herein, we focus on the recognition, mechanism, and inhibitors of NNMT with emphasis on key advancements in the field. We also discuss future directions for the development of NNMT inhibitors.
Elimination of Low Yield with 3–9 O’clock Signature through Optimization of CMP Cleaner unit Brush Gap

Tungsten Chemical and Mechanical Polishing (CMP) is a necessary process in the ever-shrinking technology for the next generation semiconductor devices fabrication. In a manufacturing environment it is not only critical to control the wafer planarization removal rate and uniformity but also to evaluate the post process performance by examining the polished wafer surface for defects, micro-scratches, contamination, oxide erosions and dishing issues. It is an on-going challenge to improve wafer yield by eliminating these inline issues and introducing continuous improvement program (CIP) to detect and resolve them in order to reduce or eliminate the exposure to customers.In this paper we will delve into the thought process on how the low yield issue associated with the tungsten process step was resolved by enhancing the detection method both inline and following the tungsten CMP scan step, and by optimizing of the tool’s cleaner module unit brush gap to resolve the line streak signature. The subsequent elimination of the 3–9 o’clock low yield signatures only manage to unravel after an improvement sensor was installed to detect the actual wafer rpm at the brush unit during cleaning step.
Telehealth Increases Access to Brief Behavioral Interventions in Orofacial Pain Clinic during COVID-19 Pandemic: A Retrospective Study.

OBJECTIVE: Aim of the study was to test if orofacial pain patients were more likely to start and complete a brief psychological intervention for managing certain chronic orofacial pain conditions (physical self-regulation, PSR) via telehealth (during the COVID-19 pandemic) vs. in-person (prior to the COVID-19 pandemic). Exploratory aim was to describe demographic factors that may influence the patients to start and complete PSR. METHODS: Retrospective medical charts of all patients seen at a university-affiliated tertiary orofacial pain clinic between July-December 2019 (in person, pre-pandemic) and July-December 2020 (telehealth, during pandemic) were reviewed. Charts were examined for demographic information and to compare the number of patients who started and completed PSR during each study period (chi-squared test). RESULTS: Of 248 new patients seen in the clinic during 2019 period, 25 started PSR in-person (10.08%). Of 252 new patients seen during 2020 period, 53 started PSR via telehealth (21.03%). Patients were more likely to start PSR (OR = 6.21, p<.001, CI = 2.499 to 15.435) and more likely to complete all three sessions of PSR (OR = 5.69, p<.001, CI = 2.352 to 13.794) when it was offered via telehealth than in-person. Among those who started PSR via telehealth, patients from metropolitan areas were more likely to start the intervention than those from non-metropolitan areas (p=.045). CONCLUSIONS: Offering brief psychological pain interventions via telehealth in tertiary orofacial pain clinics has demonstrated feasibility and may improve willingness to participate in psychological treatments. Results need to be replicated with prospective data as modality was confounded with pandemic in the current study.
Generation of Organozinc Nucleophiles Based on the Biomass-Derived Platform Molecule 5-(Chloromethyl)furfural

5-(Chloromethyl)furfural (CMF) is a cellulose derivative of increasing appeal as a renewable platform molecule. Although its role as an electrophile has been broadly studied, little is known about ...
Thucydides and the Philosophical Origins of History

This book addresses the question of how and why history begins with the work of Thucydides. The History of the Peloponnesian War is distinctive in that it is a prose narrative, meant to be read rather than performed. It focuses on the unfolding of contemporary great power politics to the exclusion of almost all other elements of human life, including the divine. The power of Thucydides' text has never been attributed either to the charm of its language or to the entertainment value of its narrative, or to some personal attribute of the author. In this study, Darien Shanske analyzes the difficult language and structure of Thucydides' History and argues that the text has drawn in so many readers into its distinctive world view precisely because of its kinship to the contemporary language and structure of Classical Tragedy. This kinship is not merely a matter of shared vocabulary or even aesthetic sensibility. Rather, it is grounded in a shared philosophical position, in particular on the polemical metaphysics of Heraclitus.
Structure-activity relationship of reversibly lipidized peptides: studies of fatty acid-desmopressin conjugates.

Purpose. To synthesize a series of reversible fatty acid-desmopressin (DDAVP) conjugates and to study their structure-activity relationship as anti-diuretic drugs.
Abl and Cell Death

The Abl tyrosine kinase contains nuclear-import and -export signals and undergoes nucleo-cytoplasmic shuttling in proliferating cells. The nuclear Abl is activated by DNA damage or tumor necrosis factor to promote cell death through transcription-dependent and -independent mechanisms. The oncogenic BCR-ABL tyrosine kinase is defective in nuclear import and functions as an inhibitor of apoptosis in the cytoplasm. If allowed to function in the nucleus, BCR-ABL also induces cell death. Abl interacts with several different types of death effectors. However, the precise mechanism by which Abl tyrosine kinase regulates cell death remains to be determined.
Explorations in image databases

This dissertation proposes Visual Computing and Perceptual search in databases as a new discipline, largely independent on the field of computer vision on which it rests. Computer vision tries to build anthropomorphic systems that carry out some specific perceptual task in a largely independent manner. Perceptual databases, on the other hand, are social systems, whose operation only makes sense in connection with a user that guides the system and validates the results. This dissertation shows that this difference has important repercussions on all aspects of the design of an image database, from the data representation to the interface design. The second part of the dissertation proposes a mathematical model of image similarity suitable for application to "social" databases. The model is based on frames generated by discrete subgroup of a Lie group. The metric of Lie group is studied, as well as the metric of the color space in which images take values. This leads to the formulation of a theory in which image features are extremely general, and similarity criteria can be generated on the fly as a result of interaction with the user. The generality of the similarity model could overwhelm the user, and needs to be harnessed by a suitable interface design. The third part of this dissertation proposes guidelines for interface design and the design of an interface for a general purpose image database. The interface is based on the idea that the user should explore the image space looking for interesting regions, rather than asking a query and expecting a meaningful response.
The Consequences Of Information Revealed In Auctions

This paper considers the ramifications of post-auction competition on bidding behavior under different bid announcement policies. In equilibrium, players attempt to signal information to their post-auction competitors through their bids. Thus, an auctioneer can take advantage of these attempts by strategically selecting which bids to announce and which to conceal. Revenue and efficiency implications of various announcement policies are examined and used to explain the prevalence of certain auction procedures in the world today.
Numerical Modeling of Probe Velocity Effects for Electromagnetic NDE Methods

A major advantage of electromagnetic NDE methods, particularly those associated with eddy current or flux leakage inspection, is that the probe does not need to contact the testing specimen. Thus, it allows for rapid moving inspection. However, since the output NDE signals are generated by a moving probe, they are affected by the resulting motionally induced currents and may result in a false interpretation. For this reason, it is necessary to include such velocity effects in numerical field/defect interaction models.
Management of Infants Whose Mothers Have Measles

Mothers of young children occasionally develop measles.1 Because these mothers were susceptible to measles at the time their children were born, they did not transmit passive measles antibodies to their infants and the infants are also susceptible to measles. Infants whose mothers have measles are at high risk of developing severe complications because of their young age and the intense exposure; these factors have been associated with high case fatality rates in several studies.2-5 The Committee on Infectious Diseases of the American Academy of Pediatrics and the Advisory Committee on Immunization Practices of the United States Public Health Service recommend that unvaccinated household contacts of people with measles should receive immune globulin.6-7
Parental interest in comprehensive care for children with attentional concerns

Many families seek natural therapies for children. We describe what families want when they seek consultation for natural therapies for children with attention deficit hyperactivity disorder (ADHD). Our objective was to: a) describe the kinds of problems and therapies used by patients presenting with a concern about ADHD; b) assess interest in counselling about health promotion; and c) describe physician recommendations at the initial consultation about conventional and CAM therapies. We reviewed intake forms, physician reports and laboratory studies for new patients seen in an integrative paediatric clinic between January 2010 and June 2011. Of the 75 new patients, 23 (31%) families had concerns about ADHD. Of these, 70% were boys; the average age was 11.2 ± 3.1 years, and 80% received care from specialists. Eleven patients (48%) were taking a prescription medication, but only three (13%) were taking medicine for ADHD; dietary supplements were taken by 12 patients (52%). Most families were interested in health promotion information about diet (87%), exercise (78%), stress management (74%), and sleep (74%). Of 11 patients tested, 82% had low ferritin. Recommendations focused on health promotion (100%), dietary supplements, such as multivitamins/minerals (71%) and omega-3 fatty acids (82%), and specialist referrals (30%). Families seeking natural therapies for children with ADHD have needs for health promotion and care coordination, which are well addressed using tools and skills already present in the medical home.
Partial γ-Ray Cross Sections for the Reaction 239Pu(n,2nγi) and the 239Pu(n,2n) Cross Section

Absolute partial γ-ray cross sections for discrete γ-ray production in the 239Pu(n,2nγi)238Pu reaction have been measured. The experiments were performed at LANSCE/WNR on the 60R neutron flight path. Reaction γ-rays were measured using the large-scale Compton-suppressed array of Ge detectors, GEANIE. The motivation for this experiment, an overview of the partial γ-ray cross-section measurement, and an introduction to the main experimental issues will be presented. The energy resolution of the Ge detectors allowed identification of reaction γ rays above the background of sample radioactivity and fission γ rays. The use of planar Ge detectors with their reduced sensitivity to neutron interactions and improved line shape was also important to the success of this experiment. Absolute partial γ-ray cross sections are presented for the 61+ → 41+ member of the ground state rotational band in 238Pu, together with miscellaneous other γ-ray partial cross sections. The n,2n reaction cross section shape and magnitude...
Fast Photoinduced Electron Transfer from Polyalkyl- to Polyfluoro-Metalloporphyrins in Lipid Bilayer Membranes

Direct electrochemical evidence shows that photoinduced electron transfer from excited Mg−octaethylporphyrin (MgOEP) to a Mg (or Zn) complex of tetrakis(pentafluorophenyl)porphyrin (TFPP) in lipid bilayers occurs with a second-order rate constant ≥108 M-1 s-1. This reaction is ∼100 fold faster than the reported intermolecular rate between porphyrins, and occurs even under aerobic conditions. Electron transfer from the ground state of MgOEP to excited ZnTFPP is observable under anaerobic conditions, but the rate is ∼10-fold slower. Time-resolved photoconductivity of the lipid bilayer with the mixed metalloporphyrins suggests that the charge recombination times (τ) of the geminate ion pairs in the MgTFPP−MgOEP and ZnTFPP−MgOEP systems are 20 and 38 μs, respectively. The MgTFPP- anion reduces O2 with a second-order rate constant of ∼107 M-1 s-1, but the oxidation of ZnTFPP- anions by O2 is very slow. The differences between the two systems may arise from different redox potentials of ZnTFPP and MgTFPP. These...
Toward a Mechanistic Understanding of Human Decision Making Contributions of Functional Neuroimaging

This article considers the contribution of functional neuroimaging toward understanding the computational underpinnings of human decision making. We outline the main processes likely underlying the capacity to make simple choices and describe their associated neural substrates. Relevant processes include the ability to encode a representation of the expected value or utility associated with each option in a decision problem, to learn such expectations through experience, and to modify action selection in order to choose those actions leading to the greatest reward. We provide several examples of how functional neuroimaging data have helped to shape and inform theories of decision making over and above results available from traditional behavioral measures.
Anhydroretinol, a retinoid active in preventing mammary cancer induced in rats by N-methyl-N-nitrosourea

As determined by in vitro tests, anhydroretinol, a metabolic product of retinol, was bound specifically by serum retinol-binding protein and by cellular retinol-binding protein but not by cellular retinoic acid-binding protein or the nuclear receptors, RARs and RXRs. For rats dosed with the mammary carcinogen, N-methyl-N-nitrosourea (45 mg/kg body weight) and given diets containing either the retinoid vehicle, anhydroretinol (67, 134, 268, or 536 mg/kg of diet), or retinyl acetate (328 mg/kg of diet), there were, over a 90-day observation period, no significant differences in body weights. The compound did not accumulate in liver tissue or cause an increase in hepatic levels of retinyl palmitate (potential problems observed with other retinoids). The numbers of mammary cancers were as follows: no retinoid, 4.5/rat; retinyl acetate, 2.1/rat; and increasing doses of anhydroretinol, 2.9, 3.3, 3.0, and 1.7/rat, respectively. Thus, anhydroretinol, at non-toxic levels, was effective as a preventive agent in this experimental model of breast cancer.
Mitotic hyperploidy for chromosomes VIII and III in Saccharomyces cerevisiae

The arg4–8 and cup1s markers comprise a copy-number-dependent signal device in the yeast Saccharomyces cerevisiae. These alleles permit reliable discrimination between euploid and disomic haploids as well as between euploid and trisomic diploids. To investigate and compare inherent inter-chromosomal differences as regards propensity for hyperploidy, we transplaced arg4–8 and cup1s by deleting them from chromosome VIII and then re-introducing them at the leu2 locus on chromosome III. The rate of chromosome gain was significantly greater for the chromosome III construct compared to the native chromosome VIII, in both diploid and haploid strains. In addition, more coincident aneuploidy for other chromosomes was found among chromosome VIII hyperploids compared to chromosome III hyperploids.
Rootless cones on Mars indicating the presence of shallow equatorial ground ice in recent times

High resolution Mars Orbiter Camera (MOC) images have revealed the existence of clusters of small cones in the Cerberus plains, Marte Valles, and Amazonis Planitia, Mars. These cones are similar in both morphology and planar dimensions to the larger of Icelandic rootless cones, which form due to explosive interactions between surficial lavas and near-surface groundwater. Impact crater size-frequency relationships indicate that surfaces upon which the cones sit are no older than 10 Ma. If martian cones form in the same manner as terrestrial rootless cones, then equatorial ground ice or ground water must have been present near the surface in geologically recent times.
Research nurse manager perceptions about research activities performed by non-nurse clinical research coordinators.

Abstract Objectives There has been limited research to document differences in roles between nurses and non-nurses who assume clinical research coordination and management roles. Several authors have suggested that there is no acknowledged guidance for the licensure requirements for research study coordinators and that some non-nurse research coordinators may be assuming roles that are outside of their legal scopes of practice. There is a need for further research on issues related to the delegation of clinical research activities to non-nurses. Methods This study used nominal group process focus groups to identify perceptions of experienced research nurse managers at an academic health science center in the Southern United States about the clinical research activities that are being performed by non-nurse clinical research coordinators without supervision that they believed should only be performed by a nurse or under the supervision of a nurse. Results A total of 13 research nurse managers volunteered to be contacted about the study. Of those, 8 participated in two separate nominal group process focus group sessions. The group members initially identified 22 activities that they felt should only be performed by a nurse or under the direct supervision of a nurse. Conclusions After discussion and clarification of results, activities were combined into 12 categories of clinical research activities that participants believed should only be performed by a nurse or under the direct supervision of a nurse.
Latino Mobilization and Vote Choice in the 2000 Presidential Election

Previous scholarship on Latino politics has demonstrated that mobilization has a statistically significant effect on voter turnout, suggesting the importance of get-out-the-vote campaigns to increase Latino political participation. Although nonpartisan organizations exist to mobilize Latino voters, most of the phone calls are made by political parties and candidates. I argue that the real test of effectiveness for partisan mobilization is vote choice. Using data from the 2000 presidential election, I model vote choice to determine whether or not Latinos who were contacted by Democrats and Republicans were more likely to vote for Al Gore and George W. Bush. I find that party mobilization by other Latinos is crucial to influencing vote choice. Specifically, Latinos who were contacted by Latino Republicans were significantly more likely to prefer Bush, whereas Latinos who were contacted by non-Latino Republicans were significantly less likely to prefer Bush. Several models are explored.
Cloning of the Epstein-Barr Virus-Related Rhesus Lymphocryptovirus as a Bacterial Artificial Chromosome: a Loss-of-Function Mutation of the rhBARF1 Immune Evasion Gene

Rhesus macaques are naturally infected with a gammaherpesvirus which is in the same lymphocryptovirus (LCV) genus as and closely related to Epstein-Barr virus (EBV). The rhesus macaque LCV (rhLCV) contains a repertoire of genes identical to that of EBV, and experimental rhLCV infection of naive rhesus macaques accurately models acute and persistent EBV infection of humans. We cloned the LCL8664 rhLCV strain as a bacterial artificial chromosome to create recombinant rhLCV for investigation in this animal model system. A recombinant rhLCV (clone 16 rhLCV) carrying a mutation in the putative immune evasion gene rhBARF1 was created along with a rescued wild-type (rWT) rhLCV in which the rhBARF1 open reading frame (ORF) was repaired. The rWT rhLCV molecular clone demonstrated viral replication and B-cell immortalization properties comparable to those of the naturally derived LCL8664 rhLCV. Qualitatively, clone 16 rhLCV carrying a mutated rhBARF1 was competent for viral replication and B-cell immortalization, but quantitative assays showed that clone 16 rhLCV immortalized B cells less efficiently than LCL8664 and rWT rhLCV. Functional studies showed that rhBARF1 could block CSF-1 cytokine signaling as well as EBV BARF1, whereas the truncated rhBARF1 from clone 16 rhLCV was a loss-of-function mutant. These recombinant rhLCV can be used in the rhesus macaque animal model system to better understand how a putative viral immune evasion gene contributes to the pathogenesis of acute and persistent EBV infection. The development of a genetic system for making recombinant rhLCV constitutes a major advance in the study of EBV pathogenesis in the rhesus macaque animal model.
Virtual Agent Perception in Multi-agent Based Simulation Systems

In this paper we discuss a modular multi-sense perception system for DIVAs virtual agents. It is based on the idea that local environmental in???uences are constantly sensed by one or more of an agent’s senses (sight, hearing, smell, etc.). The perception system is extensible and modifiable and allows users to dynamically modify how an agent perceives its environment at execution time. This paper focuses on the modularity of the agent perception architecture rather than the perception algorithms themselves.
Synthesis and characterization of ion separated MU2(OBut)9 species where MNBun4, PPh4, Ph3PMe and K-dibenzo-18-crown-6

Abstract Reaction of the molecular species KU2(OBut)9 with bromide salts of non-coordinating counter-cations, MBr (M=NBun4, PPh4 and Ph3PMe)in THF solution results in the precipitation of KBr and the formation of the ion separated MU2(OBut)9 salts. The potassium cation can also be removed from the coordination sphere of the dinuclear uranium anion by reaction with dibenzo-18-crown-6 ether in THF. These compounds have been characterized by 1H NMR and electronic absorption spectroscopy. 1H NMR indicates that the dinuclear face- shared bioctahedral structure of the U2(OBut)9 anion is retained in the ion separated species. Comparison of the electronic absorption spectra of KU2(OBut)9 with the dinuclear U2(OBut)9 anion in solution also supports this conclusion.
Onsite Basic Health Screening and Brief Health Counseling of Chronic Medical Conditions for Veterans in Methadone Maintenance Treatment

Background In order to improve the delivery of health services for chronic medical conditions in our methadone clinic, we added an onsite health screening and brief health counseling to the treatment plans for patients receiving methadone maintenance treatment at the Atlanta Veterans Affairs Medical Center (VAMC). We then conducted a follow up retrospective chart review to assess whether this intervention improved health outcome for those patients.
Social Studies Research and the Interests of Children.

(1997). Social Studies Research and the Interests of Children. Theory & Research in Social Education: Vol. 25, No. 4, pp. 500-505.
Evaluation of Obstructive Sleep Apnea by Polysomnography Prior to Pediatric Adenotonsillectomy

Sleep-related breathing disorders range in disease severity from primary or simple snoring through upper airway resistance syndrome (UARS) and, at the severe end of the spectrum, obstructive sleep apnea syndrome (OSAS). Typical nighttime signs of a sleep-related breathing disorder include snoring, pauses in the breathing (apneic episodes), gasping, restless sleep, and, sometimes, enuresis. Daytime symptoms may include excessive daytime somnolence, but, in children, unlike adults, this is not a hallmark of a sleep-related breathing disorder. Some children have nonspecific behavioral difficulties, such as hyperactivity, developmental delay, rebelliousness, and aggressive behavior. In severe cases, children may grow poorly and can develop hypertrophy of the right side of the heart and cor pulmonale. Adenotonsillar hypertrophy is the most common cause of a sleeprelated breathing disorder in an otherwise healthy child. Tonsillectomy and adenoidectomy (T&A) is the most common treatment, with well-recognized resolution of the symptoms. The diagnosis of a significant sleep-related breathing disorder in childhood may be challenging due to the variety of presenting symptoms. Polysomnography (PSG) is recognized as the most useful laboratory test to assess the presence and severity of this condition. This article examines whether every child with the symptoms and signs of a sleep-related breathing disorder should undergo PSG to confirm the diagnosis of OSAS prior to T&A.
Promoter sequences from a maize pollen-specific gene direct tissue-specific transcription in tobacco.

A set of 5′ promoter deletions from Zmgl3, a genomic clone of a pollen-specific gene of maize, has been transcriptionally fused to a β-glucuronidase (GUS) reporter gene in the binary vector pBI101. Tobacco leaf disks were transformed and mature plants analyzed for GUS activity directed by the Zmg13 promoter constructs. Transgenic plants containing the 375 by Zmg13 sequence from −314 to +61 relative to the transcription start site transcribed GUS RNA and expressed active GUS enzyme in mature pollen but not in leaves. Plants transformed with a 35S CaMV promoter-GUS transcriptional fusion expressed GUS RNA in leaves but not in pollen. Neither GUS RNA or active enzyme could be detected in pollen or leaves from plants containing a 124 by Zmg13-GUS transcriptional fusion missing the putative Zmg13 TATA box. No GUS RNA or enzyme expression was not detected in non-transformed tobacco. RNA and GUS histochemical analysis of the T1 generation confirmed that the temporal expression pattern of Zmg13-GUS transcription in tobacco followed that of the native gene in maize and that the Zmg13 promoter sequences from the maize gene are able correctly to direct genetically stable, tissue-specific gene expression in transgenic tobacco plants.
The Hodge Structure on a Filtered Boolean Algebra

Let Δ(Bn) be the order complex of the Boolean algebra and let B(n, k) be the part of Δ(Bn) where all chains have a gap at most k between each set. We give an action of the symmetric group Sl on the l-chains that gives B(n, k) a Hodge structure and decomposes the homology under the action of the Eulerian idempontents. The Sn action on the chains induces an action on the Hodge pieces and we derive a generating function for the cycle indicator of the Hodge pieces. The Euler characteristic is given as a corollary. We then exploit the connection between chains and tabloids to give various special cases of the homology. Also an upper bound is obtained using spectral sequence methods. Finally we present some data on the homology of B(n, k).
Electromagnetic Pulse Penetration Through Small Apertures

The electromagnetic field penetration through small apertures is discussed for general aperture shapes. Approximnate analytical expressions are obtained for the penetration fields. In particular the fields that penetrate a small aperture into the region between two parallel, perfectly conducting plates are determined and some numerical results are obtained.
Relating Weather Types to Asthma-Related Hospital Admissions in New York State

Many previous studies have looked into the relationship between asthma and individual weather variables, but comparatively few have looked at this relationship using holistic weather types (WTs). Utilizing the Spatial Synoptic Classification, this research considers up to 6 days of lag time while investigating the asthma-to-WT relationship in two age groups (under 18 and 18 and over) throughout New York State. Results indicate that a cold and dry WT in autumn corresponds to increased asthma admissions and spike days in admissions in New York City (NYC) for the school-aged population, while hot and dry WTs in summer correspond to spike days in asthma admissions in both age groups. However, results vary considerably for other regions, seasons and WTs, and spike day analysis yields clearer results than the analysis of total anomalous admissions. When stratified by multiple regions and age groups, the sample size of daily asthma admissions is a limiting factor outside of NYC.
Amplification, attenuation, and dispersion of sound in inhomogeneous flows

First order effects of gradients in nonuniform potential flows of a compressible gas are included in a dispersion relation for sound waves. Three nondimensional numbers, the ratio of the change in the kinetic energy in one wavelength to the thermal energy of the gas, the ratio of the change in the total energy in one wavelength to the thermal energy, and the ratio of the dillatation frequency (the rate of expansion per unit volume) to the acoustic frequency, play a role in the separation of the effects of flow gradients into isotropic and anisotropic effects. Dispersion and attenuation (or amplification) of sound are found to be proportional to the wavelength for small wavelength, and depend on the direction of wave propagation relative to flow gradients. Modification of ray acoustics for the effects of flow gradients is suggested, and conditions for amplification and attenuation of sound are discussed.
Elemental and/or cation ratio efficiency of corn hybrids grown on an infertile soil inadequate in magnesium

Abstract Magnesium deficiency in corn (Zea mays L.) is often attributed to the low levels of Mg in soils. This study was conducted to determine elemental and/or cation balance efficiency of corn hybrids grown on a soil low in available Mg, Among the 15 hybrids tested, no differential efficiency in ear leaf concentration of P was found at two planting dates. Leaf concentrations of Zn and Fe were influenced by planting date for all hybrids but interactions between hybrids and planting date were found only for K, Ca, Mg concentrations and the sum of the Meq Ca + Mg/100 g, the Meq K + Ca + Mg/100 g, and the K/Ca and K/Ca + Mg ratios. Planting dates did not Influence the K/Mg ratio among hybrids. Large differences in efficiency of K, Ca, and Mg were found but these cations were found to have large Interactions. Data show that Ca and Mg efficient hybrids are less efficient in K than Ca and Mg inefficient hybrids. It should be possible to breed corn hybrids for better cation balance efficiency for use on inferti...
Noise suppression now

Noise control in the Department of Defense is discussed in terms of the Noise Control Act of 1972.
"Mental imbalance" and the prediction of recurrent delinquent behavior.

Cognitive and personality patterns of 84 court-referred adolescents were examined to identify predictors of recurrent delinquent behavior. Continued behavioral problems at follow-up were more likely in adolescents with discrepancies between Verbal and Performance IQ or large differences between "neurotic" and "psychotic" scale elevations on the MMPI. Positive outcomes were most likely for adolescents who could be described as "mildly neurotic." Combining the discrepancy scores from the intelligence and personality tests with other background variables in a Bayesian conditional probability model resulted in accurate predictions of later behavior for 81% of the sample. These findings suggest that imbalances in cognitive and personality development may limit a delinquent adolescent's ability to interact appropriately with the environment.
Direct ionization of zeolites by far-UV light following electron trapping by charge balancing cation clusters

Abstract The direct excitation of Na + -zeolites such as Na + -X, -A, -Y and -sodalite by UV light of wavelengths 193 and 185 nm (6.4 and 6.7 eV) ionizes the zeolites and produces electrons trapped in ionic clusters. The process with the 185 nm light exhibits a single-photon ionization. The threshold of ionization lies between 4.9 and 6.4 eV. With this far-UV light, more trapped electron species were observed in NaX compared to γ-irradiation and fast electron (Febetron) radiolysis.
Kappa reliabilities for continuous behaviors and events

Cohen's kappa for measuring agreement between two observers using a discrete nominal scale is extended to measuring agreement over time for continuous nominal scales. The continuous kappa coefficient avoids problems encountered by the arbitrary division of real time durations into presence/absence frequencies in discrete intervals. The extension is simple but issues of independence and number of observations pose problems for significance testing.
The invasion and population outbreak of Psylloides napi (Coleoptera : Chrysomelidae) on yellow rocket (Barbarea vulgaris) in New York.

Recently we published an account on the invertebrate fauna associated with the apparently introduced cruciferous weed, Barbarea vulgaris , known as yellow rocket or winter cress (Root and Tahvanainen 1969). Since the field work for our previous study was completed, a new flea beetle, Psylloides napi (F.), of European origin has become an important component of the Barbarea fauna. To our knowledge, this invading species has not been previously reported in North America. Our identification of P. napi has been verified by Dr. A. S. Aslam at the British Museum (Natural History). A re-examination of all our collections taken from crucifers near Ithaca, N. Y., during the past 4 years has revealed that the 1st specimens of P. napi were captured in July 1966; one on a collard, Brassica oleracea , and one on B. vulgaris . Two more specimens were collected on B. vulgaris in 1967. During 1968, P. napi was relatively abundant in the vicinity of Ithaca, N. Y. R. Wills Flowers (personal communication) also found this species on B. vulgaris in Berkshire Co., Mass, in early June 1968. During 1969, P. napi reached the level of a serious infestation in upstate New York and presently it is the most common and constant herbivore feeding on B. vulgaris . We started a quantitative study of this species in 1969. This work is being continued.2
Imperium in Imperio and the Political Origins of the American Labor Conspiracy Doctrine

Many political essayists and judges writing in the early republic sought to circumscribe actions deemed oppressive and otherwise interfering with civil liberty. Associations seeking to advance a set of narrow interests at the expense of the public posed a threat to civil liberty. The way that threat was interpreted in the specific case of labor associations is the subject of this article. It was not the economic power of such entities that gave rise to indictments. Rather the political significance of “private confederacies” acting as an “imperium in imperio” was cited as the key threat to the new political order. Thus, Judge Levy in granting legitimacy to the American labor conspiracy laws did not cite common law precedent but his concern that “a new legislature consisting of journeymen shoemakers” would usurp the legitimate power “of our state legislatures.”
Prevalence of roll-over protective structure (ROPS)-equipped tractors on Hispanic-operated farms in the United States

ABSTRACT Roll-over protective structures (ROPS) are known to prevent tractor overturn deaths, but not enough tractors are equipped with them in the United States to reduce the rate of these deaths to levels seen in several European countries. Recent literature has defined the use of ROPS on US farms in general, but little is known about ROPS use on Hispanic farm operations. Data from a national survey for the calendar year 2003 were used to assess the prevalence of ROPS use on Hispanic-operated farms. Farm characteristics previously identified to be associated with low ROPS prevalence rates on other farming operations were examined for these Hispanic farming operations. The overall ROPS prevalence rate on Hispanic farms was 52.2%. Adjusted odds ratios of potential risk factors found that the region where the farm was located and the acreage of the farm appeared to be the most significant indicators of the prevalence of ROPS on Hispanic farms. In addition, the age of the farm operator, the farm status as a...
Low-level mercury in children: associations with sleep duration and cytokines TNF-α and IL-6.

There is a sizeable literature suggesting that mercury (Hg) exposure affects cytokine levels in humans. In addition to their signaling role in the immune system, some cytokines are also integrally associated with sleep behavior. In this cross-sectional study of 9–11 year old children (N=100), we measured total blood Hg in whole blood, serum levels of tumor necrosis factor α (TNF-α) and interleukin 6 (IL-6), and objectively measured sleep and activity using actigraphy. Increasing blood Hg was associated with significantly shorter sleep duration and lower levels of TNF-α. IL-6 was not associated with sleep or blood Hg. This study is the first to document an association between total blood Hg and sleep (albeit a small effect), and the first to consider the associations of total blood Hg with cytokines TNF-α and IL-6 in a pediatric sample. Further research using alternative designs (e.g., time-series) is necessary to determine if there is a causal pathway linking low-level Hg exposure to sleep restriction and reduced cytokines.
Incidence and types of preventable adverse events in elderly patients: population based review of medical records

Abstract Objectives: To determine the incidence and types of preventable adverse events in elderly patients. Design: Review of random sample of medical records in two stage process by nurses and physicians to detect adverse events. Two study investigators then judged preventability. Setting: Hospitals in US states of Utah and Colorado, excluding psychiatric and Veterans Administration hospitals. Subjects: 15 000 hospitalised patients discharged in 1992. Main outcome measures: Incidence of preventable adverse events (number of preventable events per 100 discharges) in elderly patients (65 years old) and non-elderly patients (16-64 years). Results: When results were extrapolated to represent all discharges in 1992 in both states, non-elderly patients had 8901 adverse events (incidence 2.80% (SE 0.18%)) compared with 7419 (5.29% (0.37%)) among elderly patients (P=0.001). Non-elderly patients had 5038 preventable adverse events (incidence 1.58% (0.14%)) compared with 4134 (2.95% (0.28%)) in elderly patients (P=0.001). Elderly patients had a higher incidence of preventable events related to medical procedures (such as thoracentesis, cardiac catheterisation) (0.69% (0.14%) v 0.13% (0.04%)), preventable adverse drug events (0.63% (0.14%) v 0.17% (0.05%)), and preventable falls (0.10% (0.06%) v 0.01% (0.02%)). In multivariate analyses, adjusted for comorbid illnesses and case mix, age was not an independent predictor of preventable adverse events. Conclusion: Preventable adverse events were more common among elderly patients, probably because of the clinical complexity of their care rather than age based discrimination. Preventable adverse drug events, events related to medical procedures, and falls were especially common in elderly patients and should be targets for efforts to prevent errors.
Convenient approach to the quantum mechanics of quantum-well devices

Cette approche est appliquee aux problemes des impuretes hydrogeniques entre deux plans et d'une impurete hydrogenique sur l'axe d'un fil quantique
Behavioral assessment of eating patterns and blood glucose in diabetes using the Self-Monitoring Analysis System

The Self-Monitoring Analysis System is a set of microcomputer programs that were developed to remove clinical judgment from the task of behavioral assessment using self-monitoring diaries. The program is written in Turbo Pascal and runs on MS-DOS (16-bit) or CP/M (8-bit) microcomputer systems. The program allows the user to custom design data bases with hundreds of binary, categorical, integral, and real variables. Full-screen data-entry forms can be custom designed, and random access files allow for flexible data entry and editing. The program makes extensive utilization of Pascal’s very flexible data structure capabilities. Dynamic allocation of memory allows the program to maximize its use of available RAM. Data from a patient with diabetes is presented as a case study illustrating the system’s utility.
Graphical analysis of mortgage payments

Abstract This paper presents a computer package that performs graphical analysis of mortgage. In the computational procedure, the program calculates the monthly payment, the unpaid balance, interest charge, and equity payment for each of the months of the mortgage term. Plots of unpaid balance and total equity versus time are made for a visual analysis. The program, named GAMPS, is equally applicable to any cash flow situation involving equal periodic installments. Of particular importance is the “equity break-even point” which the program also calculates. This break-even point indicates that point in time when the unpaid balance equals the cumulative equity.
Phorbol Ester-induced G1 Phase Arrest Selectively Mediated by Protein Kinase Cδ-dependent Induction of p21

Although protein kinase C (PKC) has been widely implicated in the positive and negative control of proliferation, the underlying cell cycle mechanisms regulated by individual PKC isozymes are only partially understood. In this report, we show that PKCδ mediates phorbol ester-induced G1 arrest in lung adenocarcinoma cells and establish an essential role for this novel PKC in controlling the expression of the cell cycle inhibitor p21. Activation of PKC with phorbol 12-myristate 13-acetate (PMA) in early G1 phase impaired progression of lung adenocarcinoma cells into S phase, an effect that was completely abolished by specific depletion of PKCδ, but not PKCα. Although the PKC effect was unrelated to the inhibition of cyclin D1 expression, PKC activation significantly up-regulated p21 and down-regulated Rb hyperphosphorylation and cyclin A expression. Elevations in p21 mRNA and protein by PMA were mediated by PKCδ but not PKCα. Studies using luciferase reporters also revealed an essential role for PKCδ in the PMA-induced inhibition of Rb-dependent cyclin A promoter activity. Finally, we showed that the cell cycle inhibitory effect of PKCδ is greatly attenuated by RNA interference-mediated knock-down of p21. Our results identify a novel link between PKCδ and G1 arrest via p21 up-regulation and highlight the complexities in the downstream effectors of PKC isozymes in the context of cell cycle progression and proliferation.