cssi/SciSciGPT-SciSciNet huggingface dataset:
Personality preferences of accounting students: a longitudinal case study

Abstract As the skills needed to succeed in accounting broaden, accounting programs must develop recruiting strategies to attract and retain individuals with a broader range of personality characteristics. As a form of recruitment evaluation, this study uses the Myers–Briggs Type Indicator (MBTI) to examine the characteristics of accounting students recruited into and retained by one of the original Accounting Education Change Commission (AECC) grant programs. Results indicate that, contrary to expectations, the personality types attracted to and retained in the program have not become more diverse over the course of 8 years. These results may imply that certain requisite preferences are needed to succeed in accounting or that homogeneity has benefits not previously considered. They certainly suggest a need to further refine recruiting processes, to focus on broader perceptions of the profession, to evaluate faculty's own preferences and biases and/or to develop curriculum to help students learn to utilize their less preferred personality traits.
Age and the immune response in pediatric renal transplantation.

Because renal transplant outcome is poorer in young children when compared with older children or adults, it is reasonable to question whether immune reactivity relative to renal allograft rejection differs between young children and adults. While this hypothesis is far from established, preliminary data suggest that young children may represent an immunologically-defined subgroup distinct from adults and perhaps at high risk for renal allograft rejection. From a histocompatibility standpoint, infants may show some subtle differences in HLA typing results when compared with older children or adults. Children may also be at higher risk than adults for rejection when the transplant is performed in the presence of a historically positive, currently-negative lymphocytotoxicity crossmatch. Several non-specific tests of cellular immunity have been used to characterize the strong immunologic responder, i.e. the person who has an increased tendency to vigorously reject a renal allograft. Children in general and young children in particular may fall into this group. Children 5 years old and younger have significantly increased numbers of CD2+, CD3+, and CD4+ T lymphocytes when compared with older children. Young children also have higher than expected functional indices of cellular immune function. Taken together, these data suggest that children, and particularly young children, may have a heightened immunologic responsiveness, which may in turn represent an increased propensity for allograft rejection. Appropriate modification in imunosuppression may be indicated to optimize renal transplant outcome.
Improved survival up to four years after early coronary thrombolysis

The long-term prognosis after thrombolytic therapy in patients with acute myocardial infarction (AMI) is unknown. This question was investigated in a 4-year follow-up study of 227 patients. According to the status of reperfusion at the end of the acute catheterization, the patients were divided into a patent (n = 171) and an occluded (n = 56) group. Both hospital and 4-year mortality rates were significantly reduced in the patent group by 13 and 14%, respectively (p less than or equal to 0.005 for both). Baseline variables known to be important for prognosis did not differ between the 2 groups. Patients with a patent infarct artery who underwent early acute coronary artery bypass grafting (CABG) had a greater survival (p less than 0.10) and better left ventricular function (p less than 0.01) than did patients with a patent infarct artery who did not undergo CABG. This difference was associated with a lower frequency of fatal reinfarction and cardiogenic shock in the CABG group. Thus, survival is improved up to 4 years after successful thrombolysis and appears to be further enhanced by early CABG.
A gene in the human major histocompatibility complex class II region controlling the class I antigen presentation pathway

MAJOR histocompatibility complex (MHC) class I molecules export peptides to the cell surface for surveillance by cytotoxic T lymphocytes1-3. Intracellular peptide binding is critical for the proper assembly and transport of class I molecules4–6. This mechanism is impaired as a result of a non-functional peptide supply factor gene (PSF) in several human mutant cell lines with genomic lesions in the MHC. We have now identified PSF in the MHC class II region by deletion mapping in mutants and chromosome-walking. PSF is homologous to mammalian and bacterial ATP-dependent transport proteins, suggesting that it operates in the intracellular transport of peptides.
Density functional implementation of a Gaussian-weighted operator for spin densities

We have implemented a new Gaussian-weighted operator, developed by Rassolov and Chipman, J. Chem. Phys., 1996, 105, 1470, for the calculation of spin densities, in density functional theory (DFT). Applications to the first row atoms B–F and some diatomic and polyatomic molecules are presented. The fairly good agreement with experimental values suggests that the combination of the new operator and DFT provides a useful tool to calculate this challenging property.
Structure of a helicase–helicase loader complex reveals insights into the mechanism of bacterial primosome assembly

During the initiation of bacterial DNA replication, loader proteins transfer the hexameric helicase ring onto replication origin DNA. Liu et al. report the crystal structure of a 570-kDa prepriming complex and suggest that the release of loader proteins is associated with the transition of the helicase ring to a spiral configuration.
Evaluation of Chemical Controls and Entomopathogenic Nematodes for Control of Phyllophaga White Grubs in a Fraser Fir Production Field

The results of 2 yr of field trials evaluating various chemical and biological controls of Phyllophaga anxia (LeConte) white grubs in a Fraser fir [Abies fraseri (Pursh) Poir] Christmas tree production field are reported here. Chemical insecticides evaluated included bifenthrin, chlorantraniliprole, thiamethoxam, and time-released imidacloprid tablets (Coretect, Bayer CropScience, Research Triangle Park, NC). Entomopathogenic nematodes evaluated included Heterorhabditis bacteriophora (Poinar) and Steinernema carpocapsae (Weiser). Overall, the chemical controls provided the best root protection and grub control. Targeted treatments of an insecticide in the root zone may provide adequate tree protection and can be a way to reduce overall insecticide input compared with banded sprays. The nematode H. bacteriophora provided limited root protection and grub control, whereas S. carpocapsae did not provide effective control. Differences in efficacy and persistence of the two entomopathogenic nematode species can be attributed to the biology and environmental preferences of these organisms.
What it will take: placing adolescents on the American National Agenda for the 1990s.

Abstract At the core of our efforts to develop an adolescent health agenda and to implement the goals we have discussed today is the necessity of increasing the public visibility and greater acceptability of adolescents in the greater society. Investment in this next generation should be recognized not only as valuable in itself, but in terms of its impact on future generations of children and adolescents, who themselves will become the parents of tomorrow. While those concerned with adolescents have created a number of important bridges that link disciplines, professional organizations, and communities, the focus of our efforts must also be to widen the base of this coalition to include the active involvement of the business sector and other age groups, such as the elderly. This will clearly require a variety of strategies. These efforts will be stronger if they are concurrent and mutually reinforcing, and are viewed as the constituent parts to a greater vision for the well-being of our youth.
Dynamics and management of cytopenias associated with dasatinib therapy in patients with chronic myeloid leukemia in chronic phase after imatinib failure.

BACKGROUND: The incidence, dynamics, and management of cytopenias were investigated in patients with chronic myeloid leukemia in chronic phase (CP CML) who received dasatinib therapy after imatinib failure. METHODS: Data were analyzed from 130 patients with CP CML who were treated with dasatinib from November 2003 to March 2006 in phase 1 (n = 22) or phase 2 or 3 (n = 108) studies for the development of grade 2 to 4 cytopenia (according to the National Cancer Institute Common Terminology Criteria [version 3.0]). RESULTS: Grade 2 to 4 neutropenia and/or thrombocytopenia occurred in 94 (72%) patients during dasatinib therapy and grade 3 to 4 occurred in 67 (52%) patients. Of the 94 patients who developed grade 2 to 4 neutropenia and/or thrombocytopenia, 64 (68%) also developed at least grade 2 anemia, and 16 (17%) developed grade 3 to 4 anemia. Management of cytopenias included transient dasatinib interruption in 35 (37%) patients, filgrastim in 12 (14%) patients, recombinant erythropoietin in 29 (45%) patients, and interleukin-11 in 3 (5%) patients. Factors associated with an increased risk for developing grade 2 to 4 cytopenias were longer time from diagnosis to treatment, prior interferon or imatinib therapy, and a lower white blood cell count at the initiation of dasatinib therapy. CONCLUSIONS: Hematologic toxicity was frequent during dasatinib therapy in patients with CP CML, particularly at doses >100 mg daily. Treatment interruption and/or dose reduction as well as growth factor support were found to be safe and efficacious strategies to facilitate the continuous administration of dasatinib. Cancer 2009. © 2009 American Cancer Society.
Tyrosine kinase inhibition in the modulation of tumor microenvironment to overcome immune suppression to improve immune-based therapy

ESULTS: Treatment of carcinoid cells with TTN resulted in proressive phosphorylation of GSK-3 beta, indicating a doseependent inhibition of the GSK-3 beta signaling pathway. Imporantly, TTN significantly inhibited pancreatic and pulmonary arcinoid cellular proliferation. Furthermore, inhibition of GSK-3 eta by TTN resulted in a dose-dependent reduction in CgA and SCL1, suggesting a progressive inhibition of bioactive hormone roduction.
Family environment and shame: Is there a relationship?

This study was designed to examine the relationship between dysfunctional families in childhood and shame experienced by adults and compare feelings of guilt and shame. The results indicated that the shame young adults feel is correlated with their perceived family environment as a child. Greater feelings of shame on the Test of Self-Conscious Affect (TOSCA) were correlated with lower Family Environment Scale scores on Cohesion, Expressiveness, Intellectual-Cultural Orientation, Moral-Religious Emphasis and Organization and higher Conflict scores. Other variables were also examined. The results support the hypothesis that people coming from dysfunctional families experience more shame as adults and that guilt and shame are differentially related to dysfunctional families.
Weathering: Stress and Heart Disease in African American Women Living in Chicago

Researchers have suggested that lifelong chronic and cumulative exposure to social and economic stressors is associated with early onset of chronic illness in African American women. Recent literature has demonstrated that socioeconomic aspects of neighborhoods contribute to health disparities in heart disease morbidity and mortality. In this article, the author analyzes the stories of older African American women concerning stress and other events related to heart disease, triangulated with individual- and neighborhood-level socioeconomic and environmental data, from the perspective of the weathering conceptual framework. She conducted in-depth qualitative interviews with urban, older Black women with early-stage heart disease. Women described lifelong and recent incidents of stress that they perceived as contributing to their "bad heart." The episodes described were a mixture of chronic social, environmental, and family-related challenges. Findings reveal substantial evidence supporting the weathering conceptual framework and the Sojourner syndrome in this sample of older, chronically ill Black women.
Temporal feature induction for baseball highlight classification

Most approaches to highlight classification in the sports domain exploit only limited temporal information. This paper presents a method, called temporal feature induction, which automatically mines complex temporal information from raw video for use in highlight classification. The method exploits techniques from temporal data mining to discover a codebook of temporal patterns that encode long distance dependencies and duration information. Preliminary experiments show that using such induced temporal features significantly improves performance of a baseball highlight classification system.
Stable nickel isotopes and cosmogenic beryllium‐10 and aluminum‐26 in metallic spheroids from Meteor Crater, Arizona

— The isotopic abundances of Ni in 17 metallic spheroids from Meteor Crater, Arizona, were determined by inductively coupled plasma mass spectrometry (ICP-MS). Sixteen spheroids have normal isotopic abundances. A 17th shows a marginally detectable mass fractionation of 0.40 ± 0.14 %/AMU in favor of the heavier isotopes. The general absence of mass fractionation indicates that open system evaporation caused little loss of Ni. Variable activities of the cosmogenic radionuclides 10Be and 26Al were measured by accelerator mass spectrometry in separate suites of spheroids. Activities of 26Al in most samples and of 10Be in metal cores separated from spheroids indicate that they either (1) come from greater depths in the parent meteoroid than do hand specimens, or (2) lost Al and Be during the process of spheroid formation. One individual spheroid has 10Be and 26Al activities comparable to those of bulk specimens. This result suggests that spheroid formation may occasionally include material from the outermost meter or so of the impactor. Relatively high activities of 10Be, ∼3 dpm/kg, in the siliceous shells of Canyon Diablo spheroids very likely have a meteoric origin.
A 3-D Floquet boundary condition for time-domain finite element analysis of periodic geometries

This article presents and validates a new truncation condition that is capable of absorbing all higher-order modes. This new truncation condition that we refer to as a Floquet ABC involves infinite series that need to be truncated for practical use, and a few terms in the infinite series are often sufficient to obtain very accurate results.
Fetal intervention increases maternal T cell awareness of the foreign conceptus and can lead to immune-mediated fetal demise

Fetal interventions to diagnose and treat congenital anomalies are growing in popularity but often lead to preterm labor. The possible contribution of the maternal adaptive immune system to postsurgical pregnancy complications has not been explored. We recently showed that fetal intervention in mice increases maternal T cell trafficking into the fetus and hypothesized that this process also may lead to increased maternal T cell recognition of the foreign conceptus and subsequent breakdown in maternal-fetal tolerance. In this study, we show that fetal intervention in mice results in accumulation of maternal T cells in the uterus and that these activated cells can produce effector cytokines. In adoptive transfer experiments, maternal T cells specific for a fetal alloantigen proliferate after fetal intervention, escape apoptosis, and become enriched compared with endogenous T cells in the uterus and uterine-draining lymph nodes. Finally, we demonstrate that such activation and accumulation can have a functional consequence: in utero transplantation of hematopoietic cells carrying the fetal alloantigen leads to enhanced demise of semiallogeneic fetuses within a litter. We further show that maternal T cells are necessary for this phenomenon. These results suggest that fetal intervention enhances maternal T cell recognition of the fetus and that T cell activation may be a culprit in postsurgical pregnancy complications. Our results have clinical implications for understanding and preventing complications associated with fetal surgery such as preterm labor.
Relationship between gene expression of duodenal iron transporters and iron stores in hemochromatosis subjects

To test the hypothesis that differences in duodenal iron absorption may explain the variable phenotypic expression among HFE C282Y homozygotes, we have compared relative gene expression of duodenal...
Tension-related activity in the orbitofrontal cortex and amygdala: an fMRI study with music

Tonal music is characterized by a continuous flow of tension and resolution. This flow of tension and resolution is closely related to processes of expectancy and prediction and is a key mediator of music-evoked emotions. However, the neural correlates of subjectively experienced tension and resolution have not yet been investigated. We acquired continuous ratings of musical tension for four piano pieces. In a subsequent functional magnetic resonance imaging experiment, we identified blood oxygen level-dependent signal increases related to musical tension in the left lateral orbitofrontal cortex (pars orbitalis of the inferior frontal gyrus). In addition, a region of interest analysis in bilateral amygdala showed activation in the right superficial amygdala during periods of increasing tension (compared with decreasing tension). This is the first neuroimaging study investigating the time-varying changes of the emotional experience of musical tension, revealing brain activity in key areas of affective processing.
Computational Network Model Prediction of Hemodynamic Alterations Due to Arteriolar Remodeling in Interval Sprint Trained Skeletal Muscle

Objectives: Exercise training is known to enhance skeletal muscle blood flow capacity, with high-intensity interval sprint training (IST) primarily affecting muscles with a high proportion of fast twitch glycolytic fibers. The objective of this study was to determine the relative contributions of new arteriole formation and lumenal arteriolar remodeling to enhanced flow capacity and the impact of these adaptations on local microvascular hemodynamics deep within the muscle.Methods: The authors studied arteriolar adaptation in the white/mixed-fiber portion of gastrocnemius muscles of IST (6 bouts of running/day; 2.5 min/bout; 60 m/min speed; 15% grade; 4.5 min rest between bouts; 5 training days/wk; 10 wks total) and sedentary (SED) control rats using whole-muscle Microfil casts. Dimensional and topological data were then used to construct a series of computational hemodynamic network models that incorporated physiological red blood cell distributions and hematocrit and diameter dependent apparent viscositi...
Capillary instability in nanoimprinted polymer films

Capillary forces play an active role in defining the equilibrium structure of nanoscale patterns. This effect can be especially pronounced in soft materials such as polymers near or above their glass transition temperature (Tg) where material flow is possible. In these situations, the effect of surface tension can produce varied and complex capillary instabilities, even in relatively simple geometries such as parallel-line-space grating patterns. Here we investigate a novel capillary instability that arises upon thermal annealing of nanoimprinted polystyrene line-space gratings with an underlying residual layer. This novel instability is characterized by the development of lateral undulations of the lines, culminating in the localized coalescence of adjacent imprinted lines. An exact analytic model of this undulatory instability is not tractable, but we introduce a simple physical model for this lateral instability based on the driving force to reduce the surface energy, as in the well-known Rayleigh–Plateau instability, which is likewise surface-energy driven. Good agreement is obtained between this simplified model and our observations. Our insights into the nature of this instability have implications for controlling the thermal stability of nanoscale patterns fabricated by nanoimprint lithography or other lithography techniques.
Assessment of neuropsychological trajectories in longitudinal population-based studies of children.

This paper provides a strategy for the assessment of brain function in longitudinal cohort studies of children. The proposed strategy invokes both domain-specific and omnibus intelligence test approaches. In order to minimise testing burden and practice effects, the cohort is divided into four groups with one-quarter tested at 6-monthly intervals in the 0–2-year age range (at ages 6 months, 1.0, 1.5 and 2.0 years) and at annual intervals from ages 3–20 (one-quarter of the children at age 3, another at age 4, etc). This strategy allows investigation of cognitive development and of the relationship between environmental influences and development at each age. It also allows introduction of new domains of function when age-appropriate. As far as possible, tests are used that will provide a rich source of both longitudinal and cross-sectional data. The testing strategy allows the introduction of novel tests and new domains as well as piloting of tests when the test burden is relatively light. In addition to the recommended tests for each age and domain, alternative tests are described. Assessment methodology and knowledge about child cognitive development will change over the next 20 years, and strategies are suggested for altering the proposed test schedule as appropriate.
Purified gamma-glutamyl transpeptidases from tomato exhibit high affinity for glutathione and glutathione S-conjugates.

γ-Glutamyl transpeptidases (γGTases) are the only enzymes known to hydrolyze the unique N-terminal amide bonds of reduced glutathione (γ-l-glutamyl-cysteinyl-glycine), oxidized glutathione, and glutathione S -conjugates. Two γGTases (I and II) with K m values for glutathione of 110 and 90 μm were purified 2,977-fold and 2,152-fold, respectively, from ripe tomato ( Lycopersicon esculentum ) pericarp. Both enzymes also hydrolyze dipeptides and other tripeptides with N-terminal, γ-linked Glu and the artificial substrates γ-l-glutamyl- p -nitroanilide and γ-l-glutamyl(7-amido-4-methylcoumarin). They transfer the glutamyl moiety to water or acceptor amino acids, includingl-Met, l-Phe, l-Trp,l-Ala, or the ethylene precursor 1-aminocyclopropane-1-carboxylic acid. γGTase I and II were released from a wall and membrane fraction of a tomato fruit extract with 1.0 m NaCl, suggesting that they are peripheral membrane proteins. They were further purified by acetone precipitation, Dye Matrex Green A affinity chromatography, and hydrophobic interaction chromatography. The two γGTases were resolved by concanavalin A (Con A) affinity chromatography, indicating that they are differentially glycosylated. The native and SDS-denatured forms of both enzymes showed molecular masses of 43 kD.
Systematic Review and Meta-Analysis of Methotrexate Use and Risk of Cardiovascular Disease

Inflammation predicts risk for cardiovascular disease (CVD) events, but the relation of drugs that directly target inflammation with CVD risk is not established. Methotrexate is a disease-modifying antirheumatic drug broadly used for the treatment of chronic inflammatory disorders. A systematic review and meta-analysis of evidence of relations of methotrexate with CVD occurrence were performed. Cohorts, case-control studies, and randomized trials were included if they reported associations between methotrexate and CVD risk. Inclusions and exclusions were independently adjudicated, and all data were extracted in duplicate. Pooled effects were calculated using inverse variance–weighted meta-analysis. Of 694 identified publications, 10 observational studies in which methotrexate was administered in patients with rheumatoid arthritis, psoriasis, or polyarthritis met the inclusion criteria. Methotrexate was associated with a 21% lower risk for total CVD (n = 10 studies, 95% confidence interval [CI] 0.73 to 0.87, p
Qualifications to the Rottenberg Invariance Theorem

A total of 50 years after Simon Rottenberg's article appeared in the Journal of Political Economy, his seminal article continues to be one of the most cited studies in the field of sports economics. Although his article discusses such central concepts as the Uncertainty of Outcome Hypothesis and how territorial rights are the underlying source of monopoly power, he is perhaps best known for his Invariance Theorem. Here Rottenberg states that the allocation of talent in a sports league is invariant to the ownership of property rights. This Strong interpretation of invariance, which is widely held by the profession, is predicated on a number of fairly demanding conditions. In this article, the author explores a number of these conditions, which must apply in order that Strong invariance holds. These conditions include the Daly and Moore externality problem, the critical role of transaction costs, and the impact of player preferences. Although the author respectfully acknowledges Rottenberg's Invariance Theo...
High Temperature Fluidized Bed Reactor Kinetics With Sintering Inhibitors for Iron Oxidation

High purity hydrogen is produced through a thermochemical water splitting process that utilizes iron reduction-oxidation (redox) reactions. An iron powder bed is fluidized to improve heat and mass transfer thus improving the reaction kinetics. Inert additives which act as sintering inhibitors, such as silica (SiO2) and zirconia (ZrO2), are added to the iron powder, and their effectiveness in inhibiting sintering in the oxidation step is evaluated. The influence of particle size, composition, mass fraction and bed temperature on reaction kinetics is investigated. Incorporation of zirconia in the powder bed is done by mixing it with iron powder or by coating the iron particles with a mixture of 1-3 μm and 44 μm zirconia particles. Two different batches of silica are used for blending with iron powder. The silica powder batches include particle diameters ranging from 0-45 μm and 200-300 μm. The mixing ratios of silica to iron are 0.33, 0.5, 0.67 and 0.75 by apparent volume. Experimental studies are conducted in a bench scale experimental fluidized bed reactor at bed temperatures of 450, 550, 650,750 and 850 o C. It is verified that increasing the bed temperature and the steam residence time increases the hydrogen yield. Increasing the iron particle size reduces the specific surface area and reduces the hydrogen yield. It has been found that sintering can be completely inhibited by mixing iron with 0-45 μm silica powder and maintaining the reaction temperature below 650 o C.
Heat and Moisture Advection over Antarctic Sea Ice

Abstract Surface-level meteorological observations and upper-air soundings in the Weddell Sea provide the first in situ look at conditions over the deep Antarctic ice pack in the spring. The surface‐level temperature and humidity were relatively high, and both were positively correlated with the northerly component of the 850 mb wind vector as far as 600 km from the ice edge. Since even at its maximum extent at least 60% of the Antarctic ice pack is within 600 km of the open ocean, long‐range atmospheric transport of heat and moisture from the ocean must play a key part in Antarctic sea ice heat and mass budgets. From one case study, the magnitude of the ocean's role is inferred: at this time of year the total turbulent surface heat loss can be 100 W m−2 greater under southerly winds than under northerly ones.
Conflict Resolution and Duplicate Elimination in Heterogeneous Datasets using Unified Data Retrieval Techniques

Background/Objective: Creating queries for a single search term and identifying the viable solutions for the query are the two specific problems in retrieving the data. To resolve this issue, an effective information fusion technology should be provided to obtain effective results. This paper presents a method for resolving conflicts and eliminating duplicates with increased accuracy. Methods/Statistical Analysis: Universal wrappers are designed to retrieve the actual information from the heterogeneous data sources. The process of getting input itself is modified such that the retrieved results are relevant to the context. Ranking and duplicate eliminations are done accordingly to refine the obtained results to the user. Findings: Experimental results show that the improved accuracies of the data being fetched and with reduced conflicts and duplicates. This work uses major data sources from Google, New York Times and other offline data sources. By applying the proposed data retrieval techniques, the produced data is consistent by the help of wrappers. The proposed approach improves the data consistency which is relatively better than the existing technique. Finally, this proposed research work concludes that it is used to identify and resolve the conflict data and delivers the consistent data to the users in a ranked manner. Applications/Improvements: To create a unified repository which can be used for knowledge mining and warehouse based analysis of existing data and retrieve the result.
Meniscus Tear MRI Correlation

On MRI, the diagnostic criteria for a meniscus tear include increased signal contacting the articular surface of the meniscus or abnormal morphology. Bucket-handle tears are displaced longitudinal tears and may demonstrate a fragment in the notch, double PCL, double anterior horn, and truncated meniscal body on MRI. Longitudinal tears are usually traumatic, parallel to the circumference of the meniscus, and are often reparable. The displaced portions of horizontal flap tears may be easily missed on MRI and should be specifically sought in the medial recesses, the posterior intercondylar notch, and the popliteal hiatus.
College Depression: Causes, Duration, and Coping:

Analysis of 149 responses (based on a 15% random college sample) indicated that 90% considered they were or had been depressed at college. Depression was usually moderate and of short duration and associated with boyfriend/girlfriend difficulties, other social adjustment, and grades. These students turned to friends, themselves, and parents for help. Treatment could be provided by a college.
Solvothermal Preparation of an Electrocatalytic Metalloporphyrin MOF Thin Film and its Redox Hopping Charge-Transfer Mechanism

A thin film of a metalloporphyrin metal–organic framework consisting of [5,10,15,20-(4-carboxyphenyl)porphyrin]Co(III) (CoTCPP) struts bound by linear trinuclear CoII-carboxylate clusters has been prepared solvothermally on conductive fluorine-doped tin oxide substrates. Characterization of this mesoporous thin film material, designated as CoPIZA/FTO, which is equipped with large cavities and access to metal active sites, reveals an electrochemically active material. Cyclic voltammetry displays a reversible peak with E1/2 at −1.04 V vs ferrocyanide attributed to the (CoIII/IITCPP)CoPIZA redox couple and a quasi-reversible peak at −1.45 V vs ferrocyanide, which corresponds to the reduction of (CoII/ITCPP)CoPIZA. Analysis of the spectroelectrochemical response for the (CoII/ITCPP)CoPIZA redox couple revealed non-Nernstian reduction with a nonideality factor of 2 and an E1/2 of −1.39 V vs ferrocyanide. The film was shown to retain its structural integrity with applied potential, as was demonstrated spectroel...
Design and Development of a New 37 MW Packaged Gas Turbine Power Plant

A new 37-MW, single-shaft gas turbine power plant has been designed for electric power generation, for use in either simple-cycle or combined-cycle applications. This paper describes the evolution, design features, performance, and test program.Copyright © 1979 by ASME
A motivational interviewing-based counseling intervention to increase postabortion uptake of contraception: A pilot randomized controlled trial

Abstract Objective To determine if a counseling intervention using the principles of motivational interviewing (MI) would impact uptake of long-acting reversible contraception (LARC) after abortion. Methods We conducted a pilot randomized controlled trial comparing an MI-based contraception counseling intervention to only non-standardized counseling. Sixty women 15–29 years-old were randomized. Primary outcome: uptake of LARC within four weeks of abortion. Secondary outcomes: uptake of any effective contraceptive, contraceptive use three months after abortion and satisfaction with counseling. Bivariate analysis was used to compare outcomes. Results In the intervention arm, 65.5% of participants received a long-acting method within four weeks compared to 32.3% in the control arm (p = 0.01). Three months after the abortion, differences in LARC use endured (60.0% vs. 30.8%, p = 0.05). Uptake and use of any effective method were not statistically different. More women in the intervention arm reported satisfaction with their counseling than women in the control arm (92.0% vs. 65.4%, p = 0.04). Conclusion Twice as many women in the MI-based contraception counseling intervention initiated and continued to use LARC compared to women who received only non-standardized counseling. Practice implications A contraception counseling session using the principles and skills of motivational interviewing has the potential to impact LARC use after abortion.
Reseach Status Analysis on Flashover and the Monitoring Technology of Overhead Transmission Lines under Forest Fires

The necessity of the study on flashover mechanism of overhead transmission lines under forest fires has been introduced in this paper. Fire disaster influence factors are introduced,and the research status of flashover mechanism of Overhead Transmission Lines under Forest Fires has been summarized,including the analysis and discussion of the existing test methods. Then,the present methods to monitor forest fires applied in transmission lines and its existing problems are summarized as well,and a new idea that Laser radar technology is adopted in transmission lines to monitor forest fires has been proposed. Meanwhile,it has been indicated that the combining of Satellite remote sensing technology with traditional sensor terminal monitoring methods will improve the reliability and real- time of transmission line monitoring.
Current Trends in West Indian and African Immigration and Their Impact on Assimilation

The process of migration, figures significantly in the survival repertoire of Carribean people. For example, in Montserrat, a British West Indian Island, there is a popularly quoted proverb: “Crab no walk, e’no get fat.”
Incidence of Oropharyngeal Cancer Among Elderly Patients in the United States.

Importance An escalating incidence of human papillomavirus (HPV)-related oropharyngeal squamous cell carcinoma (OPSCC) has been reported predominantly among middle-aged adults. However, HPV infection is believed to occur many years before cancer develops, and tissue studies suggest that HPV DNA is found in the majority of OPSCC diagnosed in patients 65 years or older. Objective To update the trends in OPSCC incidence using US cancer registry data, with an emphasis on age-specific trends. Design, Setting, and Participants Data from the Surveillance, Epidemiology, and End Results (SEER) database (2000-2012) were queried to compare changes in incidence and survival trends in OPSCC with selected tobacco-related cancers (larynx, oral cavity, hypopharynx, lung) and an HPV-related cancer (anus). A total of 40 264 patients who received a diagnosis of OPSCC from 2000 to 2012 were included. Elderly patients were defined as those 65 years or older. Main Outcomes and Measures The annual percentage change in OPSCC incidence from 2000 to 2012, stratified according to age group. Results Among the 40 264 patients who received a diagnosis of OPSCC from 2000 to 2012, 13 313 (33.1%) were aged 65 years or older and 80.3% were male. Significant increases in the age-adjusted incidence of OPSCC were observed during the study period for both younger adults aged 45 to 64 years (annual percentage change [APC], 2.31; 95% CI, 1.76-2.86; P P P P = .001; hypopharynx: APC, −2.44; 95% CI, −3.01 to −1.86; P P P Conclusions and Relevance The incidence of OPSCC is increasing among elderly patients in the United States, likely driven by HPV-associated cancers. Given the unique challenges related to treating elderly patients with OPSCC, their limited enrollment in clinical trials, and the aging US population, clinical studies investigating improved therapeutic strategies for elderly patients with HPV-positive OPSCC should be performed.
Declining Admission Rates And Thirty-Day Readmission Rates Positively Associated Even Though Patients Grew Sicker Over Time

Programs from the Centers for Medicare and Medicaid Services simultaneously promote strategies to lower hospital admissions and readmissions. However, there is concern that hospitals in communities that successfully reduce admissions may be penalized, as patients that are ultimately hospitalized may be sicker and at higher risk of readmission. We therefore examined the relationship between changes from 2010 to 2013 in admission rates and thirty-day readmission rates for elderly Medicare beneficiaries. We found that communities with the greatest decline in admission rates also had the greatest decline in thirty-day readmission rates, even though hospitalized patients did grow sicker as admission rates declined. The relationship between changing admission and readmission rates persisted in models that measured observed readmission rates, risk-standardized readmission rates, and the combined rate of readmission and death. Our findings suggest that communities can reduce admission rates and readmission rates in parallel, and that federal policy incentivizing reductions in both outcomes does not create contradictory incentives.
Rayleigh scattering and the internal coupling parameter for arbitrary particle shapes

Abstract A general method for calculating the Rayleigh scattering by a particle of arbitrary shape is introduced. Although analytical solutions for Rayleigh scattering exist for spheres and ellipsoids, analytical solutions for more complicated shapes don’t exist. We find that in general the Rayleigh differential cross section goes as k 4 V 2 | α ( m ) | 2 where k = 2 π / λ and λ is the wavelength, V is the volume of the particle and α ( m ) the average volume polarizability which is dependent on the shape and the complex index of refraction, m. We use existing computational techniques, the discrete dipole approximation (DDA) and the T-matrix method, to calculate the differential scattering cross section divided by k 4 and plot it vs V 2 to determine | α ( m ) | 2 . Furthermore, we show that this leads to a general description of the internal coupling parameter ρ arbitrary ′ = 2 π k V A | α ( m ) | where A is the average projected area of the particle in the direction of incident light. It is shown that this general method makes significant changes in the analysis of scattering by particles of any size and shape.
Predatory Inclusion and Education Debt: Rethinking the Racial Wealth Gap:

Analyses of the recent surge in racial wealth inequality have tended to focus on changes in asset holdings. Debt patterns, by contrast, have remained relatively unexplored. Using 2001 to 2013 data ...
Intermittency in Precipitation: Duration, Frequency, Intensity, and Amounts Using Hourly Data

AbstractIntermittency is a core characteristic of precipitation, not well described by data and very poorly modeled. Detailed analyses are made of near-global gridded (about 1°) hourly or 3-hourly precipitation rates from two updated observational datasets [3-hourly TRMM 3B42, version 7, and hourly CMORPH, version 1.0, bias corrected (CRT)] and from special runs of CESM from January 1998 to December 2013 to obtain hourly values. The analyses explore the intermittency of precipitation: the frequency, intensity, duration, and amounts. A comparison is made for all products using several metrics with a focus on the duration of events, and a new metric is proposed based on the ratio of the frequency of precipitation at certain rates (0.2–2 mm h−1) for hourly versus 3-hourly versus daily data. For all seasons and rain rates, TRMM values are similar in pattern to CMORPH, but durations are about 80%–85%. It is mainly over land in the monsoons that CMORPH exceeds TRMM rain durations. Observed duration of precipita...
Clinical Characteristics of Pyogenic Flexor Tenosynovitis in Pediatric Patients.

Purpose To characterize the clinical presentation, common pathogens, antimicrobial susceptibility, and treatment methods associated with pyogenic flexor tenosynovitis (PFT) in pediatric patients. Methods Patients who underwent surgical treatment for PFT at a large tertiary-care children's hospital between 2001 and 2015 were identified. Descriptive summary statistics were reported on patient demographics, presenting symptoms and clinical examination features, culture results, treatment strategies, and early complications. Results Thirty-two patients (71.9% male) with a mean age of 9.5 ± 5.5 years (range, 0.8–19 years) were included. At least 3 Kanavel signs were present on presentation in 62% of the cohort, with all 4 signs identified in 34%. Three children (9%) presented with 0 to 1 Kanavel signs, with semiflexed posturing of the digit as the least commonly (41%) manifested sign. The most frequently cultured organisms were methicillin-resistant Staphylococcus aureus (MRSA) (38%), methicillin-sensitive S. aureus (22%), and Pasteurella multocida (13%). Multiple organisms were cultured in 19% of cases. Intravenous antibiotics were administered for a median duration of 4 days (range, 1–16 days) in all cases. Organisms were sensitive to the initial antibiotic regimen in 81% of cases. All methicillin-resistant S. aureus infections were sensitive to vancomycin and trimethroprim-sulfamethoxazole, and 83% were sensitive to clindamycin. Incision and drainage (I&D) was performed in all cases, with 18% of patients requiring repeat I&D. Surgical approaches included limited incision (80%), midaxial incision (13%), and Bruner incision (7%). The average length of hospitalization was 5.1 days. Infection resolved in all cases without readmission. No neurovascular complications were identified. Conclusions The presence of Kanavel signs at presentation are a meaningful indicator of PFT, but are not uniformly present on examination in children and adolescents. Owing to the prevalence of antimicrobial resistance and polymicrobial infection, empirical antibiotic therapy using broad-spectrum agents with MRSA coverage is essential. In our cohort of pediatric patients with PFT of sufficient severity to warrant surgical management, prompt I&D along with culture-guided antibiotics predictably resolves infection. Type of study/level of evidence Therapeutic IV.
Physiology and treatment of hypertension

Abstract Secondary hypertension in children is a rare but important cause of morbidity and mortality. Whilst severe hypertension can be symptomatic more often it is not and blood pressure measurement is mandatory in all children at risk. The vast majority of childhood secondary hypertension is related to renal disease and treatment is with angiotensin-converting enzyme inhibitors or angiotensin receptor blockers. Primary or essential hypertension in children is being increasingly recognised. Lifestyle factors and obesity play a significant role. If long-term morbidity is to be avoided early detection assessment and intervention is required.
Suburban Dreams: Imagining and Building the Good Life

While suburbia per se has not been an object of my research, how I research—as a concrete set of material and embodied performance practices—has long been shaped in response to the rhetorical force...
Peripheral blood detection of systemic graft-specific xeno-antibodies following transplantation of human neural progenitor cells into the porcine spinal cord.

Extensive pre-clinical and clinical studies have searched for therapeutic efficacy of cell-based therapeutics in diseases of the Central Nervous System (CNS) with no other viable options. Allogeneic cells represent the primary source of these therapies and immunosuppressive regimens have been empirically employed based on experience with solid organ transplantation, attempting to avoid immune mediated graft rejection. In this study, we aimed to 1) characterize the host immune response to stem cells transplanted into the CNS and 2) develop a non-invasive method for detecting immune response to transplanted cell grafts. Human neural progenitor cells were transplanted into the spinal cord of 10 Gottingen minipigs, of which 5 received no immunosuppression and 5 received Tacrolimus. Peripheral blood samples were collected longitudinally for flow cytometry cross match studies. Necropsy was performed at day 21 and spinal cord tissue analysis. We observed a transient increase in xeno-reactive antibodies was detected on post-operative day 7 and 14 in pigs that did not receive immunosuppression. This response was not detected in pigs that received Tacrolimus immunosuppression. No difference in graft survival was observed between the groups. Infiltration of numerous immune mediators including granulocytes, T lymphocytes, and activated microglia, and complement deposition were detected. In summary, a systemic immunologic response to stem cell grafts was detected for two weeks after transplantation using peripheral blood. This could be used as a non-invasive biomarker by investigators for detection of immunologic rejection. However, the absence of a detectable response in peripheral blood does not rule out a parenchymal immune response.
Cost-effectiveness of Cognitive Behavioral Therapy for Depressed Youth Declining Antidepressants

BACKGROUND AND OBJECTIVES: Adolescents with depression identified in primary care settings often have limited treatment options beyond antidepressant (AD) therapy. We assessed the cost-effectiveness of a brief cognitive behavioral therapy (CBT) program among depressed adolescents who declined or quickly stopped using ADs. METHODS: A total of 212 youth with depression were randomly assigned to treatment as usual (TAU) or TAU plus brief individual CBT. Clinical outcomes included depression-free days (DFDs) and estimated quality-adjusted life-years (QALYs). Costs were adjusted to 2008 US dollars. Incremental cost-effectiveness ratios (ICERs) comparing CBT to TAU were calculated over 12- and 24-month follow-up periods. RESULTS: Youth randomly assigned to CBT had 26.8 more DFDs (P = .044) and 0.067 more QALYs (P = .044) on average compared with TAU over 12 months. Total costs were $4976 less (P = .025) by the end of the 24-month follow-up among youth randomly assigned to CBT. Total costs per DFD were −$51 (ICER = −$51; 95% confidence interval [CI]: −$394 to $9) at 12 months and −$115 (ICER = −$115; 95% CI: −$1090 to −$6) at 24 months. Total costs per QALY were −$20 282 (ICER = −$20 282; 95% CI: −$156 741 to $3617) at 12 months and −$45 792 (ICER = −$45 792; 95% CI: −$440 991 to −$2731) at 24 months. CONCLUSIONS: Brief primary care CBT among youth declining AD therapy is cost-effective by widely accepted standards in depression treatment. CBT becomes dominant over TAU over time, as revealed by a statistically significant cost offset at the end of the 2-year follow-up.