Use of vitamins, minerals, and nutritional supplements by participants in a chemoprevention trial.

Roswell Park Cancer Institute, State University ofNew York at Buffalo, Buffalo, New York.Supported in part by grants from the NationalCancer Institute (CA31946) to the Cancer and Leu-kemia Group B (Richard Schilsky, M.D., Chairman).The following institutions participated in the study:Cancer and Leukemia Group B (CALGB) StatisticalOfﬁce, Durham NC—Stephen George, Ph.D., sup-ported by CA33601; Cancer Centers of the Carolinas–Greenville Community Clinical Oncology Program(CCOP), Greenville, SC—Jeffrey K. Giguere, M.D.,supported by CA67663; Christiana Care Health Ser-vices, Inc. CCOP, Wilmington, DE—Irving M. Berko-witz, D.O., supported by CA45418; Community Hos-pital–Syracuse CCOP, Syracuse, NY—Jeffrey Kirsh-ner, M.D., supported by CA45389; Dana Farber Can-cer Institute, Boston, MA—George P Canellos, M.D.,supported by CA32291; Dartmouth Medical School,Norris Cotton Cancer Center, Lebanon, NH—L. Her-bert Maurer, M.D., supported by CA04326; DukeUniversity Medical Center, Durham, NC—JeffreyCrawford, M.D., supported by CA47577; Eastern Co-operative Oncology Group, Philadelphia, PA—RobertL. Comis, M.D., Chairman; Green Mountain OncologyGroup CCOP, Bennington, VT—H. James Wallace Jr.,M.D., supported by CA35091; M.D. Anderson CancerCenter, Houston, TX—John Mendelsohn, M.D.,Chairman; Massachusetts General Hospital, Boston,MA—Michael L. Grossbard, M.D., supported byCA12449; Mount Sinai Medical Center CCOP, Miami,Miami Beach, FL—Enrique Davila, M.D., supportedby CA45564; Mount Sinai School of Medicine, NewYork—James F. Holland, M.D., supported byCA04457; North Central Cancer Treatment Group,Rochester, MN—Michael J. O’Connell, M.D., Chair-man, supported by CA25224; North Shore UniversityHospital, Manhasset, NY—Daniel R. Budman, M.D.,supported by CA35279; Rhode Island Hospital, Prov-idence, RI—Louis A. Leone, M.D., supported byCA08025; Roswell Park Cancer Institute, Buffalo,NY—Ellis Levine, M.D., supported by CA02599;Southeast Cancer Control Consortium Inc. CCOP,Goldsboro, NC—James N. Atkins, M.D., supported byCA45808; Southern Nevada Cancer Research Foun-dation CCOP, Las Vegas, NV—John Ellerton, M.D.,supported by CA35421; SUNY Health Science Centerat Syracuse, Syracuse, NY—Stephen L. Graziano,M.D., supported by CA21060; Ohio State UniversityMedical Center, Columbus, OH—Clara D. Bloomﬁeld,M.D., supported by CA77658; University of Californiaat San Diego, San Diego, CA—Stephen L. Seagren,M.D., supported by CA11789; University of ChicagoMedical Center, Chicago, IL—Gini Fleming, M.D.,supported by CA41287; University of Illinois Minority-Based Community Clinical Oncology Program (MBC-COP), Chicago, IL—Jeffrey A. Sosman, M.D., sup-ported by CA74811; University of Iowa Hospitals,Iowa City, IA—Gerald H. Clamon, M.D., supported byCA47642; University of Maryland Cancer Center, Bal-timore, MD—David Van Echo, M.D., supported byCA31983; University of Massachusetts Medical Cen-ter, Worcester, MA—F. Marc Stewart, M.D., sup-ported by CA37135; University of Minnesota, Minne-apolis, MN—Bruce A. Peterson, M.D., supported byCA16450; University of Missouri/Ellis Fischel CancerCenter, Columbia, MO—Michael C. Perry, M.D., sup-ported by CA12046; University of Nebraska MedicalCenter, Omaha, NE—Anne Kessinger, M.D., sup-ported by CA77298; University of North Carolina atChapel Hill, Chapel Hill, NC—Thomas C. Shea, M.D.,supported by CA47559; University of TennesseeMemphis, Memphis, TN—Harvey B. Niell, M.D., sup-ported by CA47555; Vermont Cancer Center, Burling-ton, VT—Hyman B. Muss, M.D., supported byCA77406; Virginia Commonwealth University MBC-COP, Richmond, VA—John D. Roberts, M.D., sup-ported by CA52784; Wake Forest University School ofMedicine, Winston-Salem, NC—David D. Hurd, M.D.,supported by CA03927; Washington UniversitySchool of Medicine, St. Louis, MO—Nancy L. Bartlett,M.D., supported by CA77440; Weill Medical Collegeof Cornell University, New York—Michael Schuster,M.D., supported by CA07968.Address for reprints: Robert S. Sandler, M.D., CB#7080, 719 Burnett-Womack Building, University ofNorth Carolina, Chapel Hill, NC 27599-7080; Fax:(919) 966-2478; E-mail: rsandler@med.unc.eduThe contents of the articles are the sole respon-sibility of the authors and do not necessarily rep-resent the ofﬁcial view of the National CancerInstitute.Received May 16, 2000; revision received October18, 2000; accepted November 21, 2000.