cssi/SciSciGPT-SciSciNet huggingface dataset:
Cataract formation after initial trabeculectomy in young patients

Abstract Objective To evaluate the risk of cataract formation in young patients after initial trabeculectomy. Design Retrospective, noncomparative case series. Participants Thirty-four eyes from 27 patients undergoing initial trabeculectomy at the Glaucoma Consultation Service, Massachusetts Eye and Ear Infirmary (mean age, 43.7 years; range, 12–54 years). Intervention Follow-up averaged 42.6 months (range, 11–90 months). Methods Lens status was observed before surgery and at 3 months; 6 months; and 1, 2, 3, 4, 5, and 6 years after initial trabeculectomy. Main outcome measure The main outcome measure was defined as cataract extraction for visually significant lenticular opacifications that developed after trabeculectomy. Results The rate of cataract extraction after initial trabeculectomy was 24% (n = 8). The average time from trabeculectomy to cataract extraction was 26 months (range, 5–58 months). Progression of lenticular opacities occurred throughout the follow-up period. There was no increased rate of cataract formation in subjects with uveitic and steroid-induced glaucoma when compared with all other types of glaucoma. In the patients with both eyes in the study, the first eye was a predictor of cataract progression in the fellow eye. Conclusions Cataract is a common complication after trabeculectomy in young patients. The 24% rate of cataract extraction after trabeculectomy reported in this study is a significant risk of which young patients contemplating surgery should be aware.
Purification of Human Anti-Thyroglobulin

Human anti-thyroglobulin antibody has been partially purified from serum in good yield, using glutaraldehyde-insolubilized human thyroglobulin as a solid-phase affinity adsorbent. The final product, when labeled with 125I, was shown to bind to native and insolubilized thyroglobulin to the extent of 41% and 63%, respectively.
Single-particle Green's functions and interacting topological insulators

We study topological insulators characterized by the integer topological invariant $\mathbb{Z}$, in even and odd spatial dimensions. These are well understood in the case when there are no interactions. We extend the earlier work on this subject to construct their topological invariants in terms of their Green's functions. In this form, they can be used even if there are interactions. Specializing to one and two spatial dimensions, we further show that if two topologically distinct topological insulators border each other, the difference of their topological invariants is equal to the difference between the number of zero-energy boundary excitations and the number of zeros of the Green's function at the boundary. In the absence of interactions Green's functions have no zeros; thus, there are always edge states at the boundary, as is well known. In the presence of interactions, in principle, Green's functions could have zeros. In that case, there could be no edge states at the boundary of two topological insulators with different topological invariants. This may provide an alternative explanation to the recent results on one-dimensional interacting topological insulators.
Three Authors, One Client: A Qualitative Description of Marriage and Family Therapy Initial Case Documentation

During the client screening and initial session process at a marriage and family therapy training clinic, three types of forms are completed: a Telephone Information Form (TIF), completed by an intake coordinator; a Client Information Form (CIF), completed by the client; and a first session Progress Note (PN), completed by the therapist. The researchers examined documents from closed client files of cases seen by masters students at a university-based brief therapy training clinic. Qualitative descriptive analysis was used to explore the level of consistency in the depiction of clients’ reasons for coming to therapy within and across cases on the three forms. Findings suggest that there was a high level of consistency between and amongst cases on two of the three forms. Implications for clinical training, practice, supervision, and research are explored.
A pre-college professional development program

In this paper, we describe the results of a four-year collaborative project conducted among six higher education institutions and their partner pre-college school systems across the US. The primary goal of the project was to offer professional development to middle and high school teachers to enable those teachers to create modules and courses to excite their students about computing. The project used Alice, a software program that utilizes 3-D visualization methods, as a medium to create a high-level of interest in computer graphics, animation, and storytelling among middle and high school students, to build understanding of object-based programming. More than 100 middle and high school teachers participated in the project, with approximately 80% of those reporting that they had used what they learned during summer workshops in their classrooms during the subsequent years.
Self-induced field model for crystal twisting in spherulites

The observed twisting of crystals about the growth direction in spherulites is modeled as a response to fields generated during the crystal growth process. These fields can be compositional or mechanical. In either case, the high local field value in the melt near the interface acts to reduce the growth velocity. Twisting of the crystal about the growth direction places all portions of the growth surface in contact with melt of lower field value than would be the case for untwisted growth, thereby increasing the growth velocity. The effect of a compositional field is analyzed here, using an extension of the moving point source to compute the composition in the melt ahead of a twisting crystal. The retarding effect of the elastic twisting of the crystal is included in the analysis. Simulations using parameters for a crystallizable/uncrystallizable polyethylene blend are carried out for a crystal with thin, rectangular cross-section. The results are quantitatively and qualitatively consistent with observation. Comments on simplifications within and implications of the model are given.
Pet Obesity Management: Beyond Nutrition

Excess weight has been associated with many clinical and subclinical conditions that put a pet’s health at risk. Successful weight management programs extend beyond standard nutritional management and incorporate an understanding of human-animal interaction. Understanding the processes and dynamics of human-animal relationships can be a useful tool for practitioners in developing successful treatment plans for their clients. Obesity is a nutritional disorder requiring lifelong management; however, when veterinarians go beyond standard treatment to include an understanding of human-animal interaction, it is also one of the few conditions in veterinary medicine that is completely preventable and curable.
Texture assessment of magnetically processed iron titanate

Untextured and highly textured iron titanate specimens were produced by vacuum filtering iron titanate-ethanol suspensions in the absence and presence of a strong magnetic field, respectively, Crystallographic texture was assessed by measuring X-ray pole figures on surfaces parallel and perpendicular to the field direction for several peaks in each system, Morphological texture was assessed by measuring grain size as a function of angle to a reference direction, Results indicate that magnetic field processing imposes a strong, fiber-type texture on the order of 30 times random, with the b-axis parallel to the applied field, Additionally, morphological texturing is absent for the grain sizes studied in this work.
R x C Ecological Inference: Bounds, Correlations,Flexibility and Transparency of Assumptions

Despite its potential pitfalls, ecological inference is an unavoidable part of some quantitative settings, including US voting rights litigation. In such applications, the analyst will typically encounter two-way tables with more than two rows and columns. Although several ecological inference methods are currently available for 2 x 2 tables, there are fewer options for analysing general R x C tables, and virtually none that model counts as opposed to fractions. We propose a count R x C method that respects the bounds deterministically, that allows for complex relationships between internal cell quantities, that is easily extensible and that results from transparent assumptions. We study the method via simulation, and then apply it to an example that is drawn from the state of Texas relevant to recent redistricting litigation there.
Automatic Annotation of Planetary Surfaces With Geomorphic Labels

In this paper, we present a methodology for automatic geomorphic mapping of planetary surfaces that incorporates machine-learning techniques. Our application transforms remotely sensed topographic data gathered by orbiting satellites into semantically meaningful maps of landforms; such maps are valuable research tools for planetary science. As topographic data become increasingly available, the ability to derive geomorphic maps efficiently is becoming essential. In our proposed framework, the mapping is achieved by means of scene segmentation followed by supervised classification of segments. The two mapping steps use different sets of features derived from digital elevation models of planetary surfaces; selection of appropriate features is discussed. Using a particular set of terrain attributes relevant to annotating cratered terrain on Mars, we investigate the design choices for both segmentation and classification components. The segmentation assessment includes K-means-based agglomerative segmentation and watershed-based segmentation. The classification assessment includes three supervised learning algorithms: Naive Bayes, Bagging with decision trees, and support-vector machines (SVMs); segments are classified into the following landforms: crater floors, crater walls (concave and convex), ridges (concave and convex), and intercrater plains. The method is applied to six test sites on Mars. The analysis of the results shows that a combination of K -means-based agglomerative segmentation and either SVM with a quadratic kernel or Bagging with C4.5 yields best maps. The presented framework can be adopted to generate geomorphic maps of sites on Earth.
Contentious Pluralism: The Public Sphere and Democracy

What do peasants in eighteenth-century England, African Americans in Reconstruction-era Virginia, mothers in Nicaragua and Argentina, and contemporary transnational activists have to do with one another? They all illustrate instances where marginalized groups challenge a lack of democracy or the limitations of existing democracy. Democracy is both a process and a product of struggles against power. Both the social capital literature and literature that focuses on democracy as a product of institutions can undervalue the actions of regular people who imagine a democratic world beyond anything that actually exists. The four cases examined in this article demonstrate that marginalized groups use a variety of performative and subversive methods to uproot the public sphere from its exclusionary history as they imagine, on their own terms, democratic possibilities that did not previously exist. In so doing, they plant the seeds of a more egalitarian public politics in new times and places. This process is “contentious pluralism,” and we ask political scientists in all subfields to look to popular movements and changing political structures as they explore the promise of democracy and to rethink the gap between democracy as an ideal and the ways in which people actually experience it. The whole history of the progress of human liberty shows that all concessions yet made to her august claims have been born of earnest struggle. The conflict has been exciting, agitating, all-absorbing, and for the time being, putting all other tumults to silence. It must do this or it does nothing. If there is no struggle, there is no progress. Those who profess to favor freedom and yet deprecate agitation are men who want crops without plowing up the ground, they want rain without thunder and lightning. They want the ocean without the roar of its waters. The struggle may be a moral one, or it may be a physical one, and it may be moral and physical, but it must be a struggle. Power concedes nothing without demand. It never did and it never will. —Frederick Douglass Quotation from Dawson 2001, 259.
Adaptive filtering based on polycepstra

An adaptive filtering method is proposed for the identification of a non-Gaussian, white-noise-driven, linear, generally non-minimum-phase system. The non-minimum-phase impulse response of the system is estimated from the updated differential cepstrum parameters of the higher order cumulants (polycepstra) of the system output. The updated cepstrum parameters are obtained by utilizing higher order cumulants and an LMS (least mean squares) type algorithm. It is shown, using Monte-Carlo simulation examples, that the proposed method would perform very well at the expense of more computations. The use and effectiveness of the method in blind linear-equalization applications is demonstrated. >
The Protestant Sect Credit Machine Social Capital and the Rise of Capitalism

The new economic sociology contends that personal relationships and trust play key roles in structuring economic activity. Max Weber's 1906 essay, `Churches and Sects,' epitomizes the new economic sociology argument. The piece not only details the origins of and individual motivations behind social capital formation in sects, it also shows how congregation-based social capital facilitated the emergence of capitalism in America. I supplement Weber's work with that of contemporary scholars to provide social-capital-based explanations of capitalism in northern Italy, the Netherlands, and England, all emphasizing the significance of credit.
RNA silencing in Drosophila

RNA silencing is a highly conserved mechanism found in both the plant and animal kingdoms that is thought to protect the genome from disruption by transposons and viral integration events. Double stranded RNAs (dsRNA) produced by transposons or replicating virus result in the production of short 21-25 nucleotide double stranded RNA molecules containing a hydroxyl group on a two base-pair 3' overhang and a 5' phosphate residue. These siRNAs are the hallmark of RNA silencing, also known as post transcriptional gene silencing (PTGS) in plants, quelling in Neurospora, and RNA interference in C. elegans, Drosophila, and Dictyostelium. Remarkably these siRNAs direct the degradation of the complementary target RNA through a complicated mechanism that is just now being understood. From our studies on RNA interference in Drosophila we propose a model in which the siRNAs interact through complementarity with the target RNA and are extended by a cellular RNA-dependent RNA polymerase (RdRP) to form a critical length of dsRNA that is subsequently degraded by RNase III-related enzymes. Here, we discuss this model and the data produced in Drosophila to support it and, in turn, this model is compared to the proposed scheme for RNA silencing in mammalian systems.
A Narrative Inquiry Into Academic Experiences of Female Saudi Graduate Students at a Comprehensive Doctoral University

Saudi student enrollment in U.S. colleges and universities has nearly tripled since 2009-2010, in large part due to the King Abdullah Scholarship Program. The representation of Saudi females is also increasing due to the loosening of Saudi Arabia’s long-standing restrictions on women’s travel and acceptable fields of study and careers. This constructivist study highlights some of the academic experiences of female Saudi graduate students at a Comprehensive Doctoral University in the western United States. Challenges related to students’ insufficient English language skills, differences in their comfort levels interacting with American and Saudi men, positive relationships with both male and female faculty members, and generally positive feelings about their experiences at their university of choice emerged as themes within the data. The participants’ varied prior experiences with mixed-gendered educational environments led to differing levels of comfort with developing relationships with men.
Semantic Contract Support for E-Business Processes

Traditional business transactions are established under well-defined contracts, agreed, explicitly or implicitly, by all the parties involved. To support such transactions in the Internet (and in the Web) it is necessary to characterize all of its aspects, such as agents, contracts, roles, relationships, interactions between partners, policies, etc. This paper presents the Contract Oriented Web Services Model (COWS) - a model for an appropriate environment for E-business dialogues, implemented using Web Services. COWS is based on well-defined contracts agreed upon by all concerned parties and incorporates various levels of applicable policies. Contracts may refer to other contracts and are valid within forae, which have default global policies. A prototype web environment supporting COWS has been implemented to test the concepts that extend the discovery process. All COWS models have been specified as ontologies, using Flora- 2.
Abusive supervision and subordinate problem drinking: Taking resistance, stress and subordinate personality into account

We test hypotheses derived from two alternative perspectives regarding the association between supervisory abuse and subordinate problem drinking. Drawing from the employee resistance literature, we examine the degree to which such an association may be sensitive to variation in subordinate personality. Drawing from the stress literature, we examine the degree to which this association may be mediated by somatic stress. Multi-source data from 1473 blue-collar workers employed in 55 work units, indicates that while the main effect of abusive supervision on problem drinking is attenuated under conditions of high subordinate conscientiousness and agreeableness (consistent with a resistance-based explanation), the main effect is not mediated by somatic stress.
Peripheral estrogen receptor-α selectively modulates the waveform of GH secretory bursts in healthy women

Estradiol (E2) drives growth hormone (GH) secretion via estrogen receptors (ER) located in the hypothalamus and pituitary gland. ERα is expressed in GH releasing hormone (GHRH) neurons and GH-secre...
Active galaxies and the diffuse Gamma-Ray background

A model for the origin of relativistic particles and gamma rays in active galactic nuclei and quasars, together with recent HEAO-1 observations of the spectra of active galaxies from 2 to 165 keV, provide the basis for a reexamination of the nature of the extragalactic gamma ray background. Active galaxies account for the observed background if their X-ray spectra steepen to E.021 above 100 keV, as observed in Cen-A, together with a further steepening to E.021 as a result of absorption of gamma rays by photon-photon pair production interactions with X-ray photons. The compactness of active galaxies required to give this steepening is consistent with estimates of their typical luminosity and radius.
Lateral eye-movement responses to visual stimuli.

The association of left lateral eye-movement with emotionality or arousal of affect and of right lateral eye-movement with cognitive/interpretive operations and functions was investigated. Participants were junior and senior students enrolled in an undergraduate course in developmental psychology. There were 37 women and 13 men, ranging from 19 to 45 yr. of age. Using videotaped lateral eye-movements of 50 participants' responses to 15 visually presented stimuli (precategorized as neutral, emotional, or intellectual), content and statistical analyses supported the association between left lateral eye-movement and emotional arousal and between right lateral eye-movement and cognitive functions. Precategorized visual stimuli included items such as a ball (neutral), gun (emotional), and calculator (intellectual). The findings are congruent with existing lateral eye-movement literature and also are additive by using visual stimuli that do not require the explicit response or implicit processing of verbal ques...
Simple Rules for Designing Business Models

Innovation in business model design is attracting increasing attention from companies. This article develops a road map that will enable firms to choose from one of four types of generic business models as their primary focus and then go through a systematic process to consider multiple design configurations for their business model and use decision protocols to choose the design that has a high probability of success.
A Dynamic and Stochastic Model of Price Leadership

This paper examines the optimal output strategy of a dominant firm or a cartel attempting to maximize the present value of its stream of profits from a market with potential entry. The rate of entry into the industry is assumed to be a function of the current price only and entry is defined as an increase in output from competitors which might or might not be already in the market. In the dominant firm model, the dominant firm quotes the market price and competitors supply all they want at that price. The dominant firm then supplies the demand not met by rivals at the given price. If the barriers to entry are great, the dominant firm can produce the short run profit maximizing level of output with little fear of losing its market share. However if entry is relatively easy, the firm can increase its output to the point where the price corresponding to aggregate industry supply induces no entry. This price has been defined as the limit price.
Absence of Higher-Order Corrections in the Anomalous Axial-Vector Divergence Equation

We consider two simple field-theoretic models, (a) spinor electrodynamics and (b) the $\ensuremath{\sigma}$ model with the Polkinghorne axial-vector current, and show in each case that the axial-vector current satisfies a simple anomalous divergence equation exactly to all orders of perturbation theory. We check our general argument by an explicit calculation to second order in radiative corrections. The general argument is made tractable by introducing a cutoff, but to check the validity of this artifice, the second-order calculation is carried out entirely in terms of renormalized vertex and propagator functions, in which no cutoff appears.
Bud Dormancy in Perennial Plants: A Mechanism for Survival

Dormancy in vegetative buds of perennial plants plays an important role for surviving harsh environmental conditions. Identifying the genetic and physiological mechanisms regulating dormancy in these vegetative structures will allow manipulation of plant growth and development in both crops and weeds. Model plants have been used to study the physiological effects that photoperiod and temperature impart on dormancy regulation in perennial buds. At the molecular level, models derived through analysis of the transcriptome have shed new light on multiple cellular pathways and physiological processes associated with dormancy transitions and, in some cases, have revealed overlap with pathways regulating flowering and cold acclimation. In this chapter, we discuss proposed models based on advances to our understanding of physiological and molecular factors affecting dormancy regulation in vegetative buds of perennials.
Thoughts on “How Brains May Work”: The Truism, the Guess, and the Prediction

Glia are much more respectable than they were in the old days. Now I will try to make more respectable still another often-slighted aspect of brain function, by identifying what I think is an excellent way to search for answers to one of the most important questions about how brains work.
Alcohol Policies and Motor Vehicle Injury Fatalities Among Underage Youth in the United States

ALCOHOL POLICIES AND MOTOR VEHICLE INJURY FATALITIES AMONG UNDERAGE YOUTH IN THE UNITED STATES Scott Evan Hadland, MD, MPH, Ziming Xuan, ScD, Jason Blachette, MPH, Vishnudas Sarda, MPH, Monica H. Swahn, PhD, Timothy C. Heeren, PhD, Timothy S. Naimi, MD, MPH Boston Children's Hospital / Harvard Medical School; Boston Children's Hospital; Georgia State University; Boston University School of Public Health; Boston Medical Center
CALCIFICATION ADJACENT TO THE PISIFORM BONE

Pain over the pisiform bone and weakness of grip are the characteristic symptoms of the clinical syndrome of calcified pisiform bursitis. The calcific deposit is adjacent to the pisiform bone and is located either within the tendon of the flexor carpi ulnaris or within the bursa of the flexor carpi ulnaris muscle. The diagnosis is frequently missed because the calcification is usually demonstrated only on oblique roentgenograms of the wrist. Surgical excision of the calcification should be resorted to only if more conservative treatment fails to give relief. The majority of patients with this condition are promptly cured by local infiltration of the calcified area.
Balancing Act: Tax Reform Options for Illinois

The authors evaluate Illinois' tax system and propose reforms. Middle- and low-income Illinoisans are taxed more heavily as a share of their income than better-off citizens of the state, the authors write.
Nonlinear Dynamics of Curved Beam: Parametric Space Classification

Future hypersonic aircraft structure requires enhanced performance, reduced maintenance and shorter turn-around times for persistent strike capabilities. Such development requires further understanding of the hypersonic environment and its interaction with the vehicular structures. A study of the effect of combined harmonic and random excitation of a curved beam, representative of aircraft structure, is presented. A classification of the loading parametric space is developed to understand the trade-offs in the response of the model. Bifurcation diagrams and phase portraits are used to comprehend the complete response dynamics. Further, increased levels of random excitation in conjunction with harmonic loading are studied for its effect on the definition of the parameter space boundaries. The understanding of the representative curved structure’s response to the parameters associated with the operational environment is essential for the design of structures for hypersonic aircrafts of the future.Copyright © 2009 by ASME
The structure of NaPt3O4.

Eine mikrokristalline Platinverbindung der Formel NaPt3O4 wird beschrieben. Alle Platinatome sind gleichwertig und die Koordinationen sind die folgenden: Platin 4 O und 2 Pt; Sauerstoff: 3 Pt und 2 Na; Natrium: 8 O. Die Substanz ist ein ionischer Leiter.
The Use of University Resources in Foreign Policy Research

My purpose in these remarks is to call on the Federal Government and its various agencies-both legislative and executive-to make a major commitment to a new kind of basic research. What I am advocating is a large-scale investment in behavioral science research, centered in the universities, and concerned with foreign policy issues and foreign areas. The research would be marked by two central characteristics: (1) It would be a completely and genuinely independent effort, built on the understanding that any assumptions may be freely entertained, no matter how heretical they might appear, and any ideas may be fully pursued, no matter where they might ultimately lead. (2) It would be defined as a task for the international community of behavioral scientists, so that, to the maximum degree possible, research would be designed, reviewed, carried out, and analyzed by American scholars in collaboration with their colleagues from other parts of the world. I shall try to show why such an investment in an independent and international research effort is of crucial importance to our society. I will then proceed to point to the almost total absence of government support for such research at the present time, using Project Camelot and its aftermath as points of reference for the distance that we have yet to travel. Finally, I shall spell out some of
The Science of Freedom: Hegel's Critical Theory

I am daily ever more convinced that theoretical work accomplishes more in the world than practical work. Once the realm of representation is revolutionized, actuality will not hold out. It is a sheer obstinacy, the obstinacy which does honor to mankind, to refuse to recognize in conviction anything not ratified by thought. Hegel Both Marx, the founding father of what later came to be known as critical theory, and those who follow in his footsteps, regard critical theory as distinctive in that it will combine the critically normative dimension of traditional philosophy with the strict attentiveness to given facts (to “the real … material world”) definitive of modern empirical science. Critical theory contends that its unique fusion of science and philosophy will overcome their respective defects, correcting both the uncritical passivity of natural science and the speculative utopianism of philosophy. By so doing, it promises to give birth to a new kind of theory with emancipatory power. Critical theorists from Marx to Habermas also see a thoroughgoing critique of Hegel as decisive for a critical theory. In their view, whatever insights Hegel may otherwise have provided, his philosophy is irreparably flawed because of its methodological commitment to a speculative method which cuts theory loose from reality and leads it to a distorted, mystically idealistic view of the human condition which is at once both Utopian and quietistic. According to critical theorists, Hegel's fundamental theoretical error lay in privileging the ideal over the real; because he does that, he is unable to get reality right. Consequently, he can neither comprehend freedom properly, as a normatively critical concept, nor understand the real conditions for freedom inherent in the status quo.
Genomic data mining enhanced by symbolic manipulation of Boolean functions

Today, more and more large-scale genomic data sets are being produced by various high-throughput technologies, and genomic data mining has never been more important. Clustering is an unsupervised learning technique that has been popular in data analysis. Although there is mature statistical literature on clustering, new types of genomic data such as gene expression data have sparked development of multiple new methods. Specifically, the technique of biclustering refers to a method that performs simultaneous clustering of rows and columns in a data matrix identifying patterns that appear in the form of (possibly overlapping) submatrices. Although this method has some clear advantages over conventional clustering techniques, it has been challenging to develop an efficient biclustering algorithm, since the problem of biclustering is inherently intractable and hard to approximate. In the first part of this dissertation, a novel biclustering algorithm based upon the symbolic manipulation of Boolean functions is presented. This algorithm exploits the zero-suppressed binary decision diagrams (ZBDDs) to implicitly represent and manipulate massive intermediate data that occur in the biclustering process. Leveraged by the ZBDDs, the proposed algorithm can find all the biclusters that satisfy specific input parameters. The second part discusses the application of this algorithm to various genomic data mining tasks such as analyzing gene expression data, linking clinical traits with related genes, and predicting microRNA regulatory modules. The experimental results demonstrate that the proposed method outperforms the alternative techniques tested---in terms of response time, the number of biclusters that can be found, and more importantly, how accurately the discovered biclusters conform to the known biological knowledge.
High efficiency transfection of embryonic limb mesenchyme with plasmid DNA using square wave pulse electroporation and sucrose buffer.

Micromass cultures of primary embryonic limb mesenchyme are a valuable model system for studying cartilage formation in vitro. However, high efficiency introduction of plasmid DNA into this hard-to...
Applying Unison, a generic framework for hapto-visual application developments, to an e-commerce application

We introduce Unison, a generic framework that serves to standardize the development of hapto-visual applications by providing a fixed set of services to the developer, independently of his or her choice of graphic and haptic software and hardware. Subsequently, we introduce an e-commerce application, namely a virtual car showroom, and discuss how it is developed within Unison. Finally we analyze the pros and cons of Unison as applied to the aforementioned application and contrast the application development process within Unison to the otherwise highly unique and custom development process completed outside our generic framework.
Effect of exercise on quality of life during and after treatment for breast cancer: Results of two randomized controlled trials.

A169 Due to the combined influences of increased incidence and improved survival, there are an estimated 2.3 million breast cancer (BC) survivors in the US. Many experience unpleasant physical side effects and reduced quality of life (QOL) that may linger for several years or longer. Exercise may be a useful tool to help women rebound psychologically and physically from BC diagnosis and treatment, however, the data from the majority of studies on the effects of physical activity (PA) on psychosocial QOL in this population have limitations such as small sample sizes, non-experimental designs, short intervention periods, poor measurement of adherence, and failure to comprehensively assess QOL. Addressing these issues will allow for a better understanding of the potential role of PA in BC survivorship. PURPOSE: To examine the effect of PA on multiple dimensions of QOL and physical functioning among 125 BC survivors participating in two randomized exercise trials in CT. METHODS: The Yale Exercise and Survivorship (YES) Study is an ongoing trial of supervised PA vs. usual care among 75 BC survivors who have completed adjuvant treatment. The Increasing or Maintaining Physical Activity during Cancer Treatment (IMPACT) Study is an ongoing 6-month trial of home-based PA vs. usual care among 50 recently diagnosed BC survivors. The goal for exercise group participants in both studies is 30 minutes of moderate-intensity PA 5 days/week. Participants completed QOL measures prior to randomization and again 6 months post-randomization. RESULTS: As of Sept. 5, 2006, 59 women have completed 6 months in the YES Study and 34 women have completed 6 months in the IMPACT Study. In pooled analyses, exercisers experienced benefits in happiness (p=.08), SF-36 mental well-being (p
How to Develop a Cardio-Oncology Clinic

Cardiovascular demands to the care of cancer patients are common and important given the implications for morbidity and mortality. As a consequence, interactions with cardiovascular disease specialists have intensified to the point of the development of a new discipline termed cardio-oncology. As an additional consequence, so-called cardio-oncology clinics have emerged, in most cases staffed by cardiologists with an interest in the field. This article addresses this gap and summarizes key points in the development of a cardio-oncology clinic.
Staffing: Building Your Human Resources Capability

The Skoll World Forum on Social Entrepreneurship has been held every spring since 2004 in stately Oxford, England. The Forum is co-produced by the Skoll Foundation, which was founded by Jeff Skoll, the first President of eBay, and the Skoll Centre at the University of Oxford which was founded with an initial investment from this philanthropist. The Forum is used, in part, to announce the annual Skoll Foundation Award Winners—a group of accomplished social entrepreneurs who have been chosen to receive new, multiyear funding from the foundation. Many of the “big name” social entrepreneurs treat the Forum as a kind of “Academy Awards” event and attend every year, using it as a time to network, fundraise, and learn from one another. I have had the privilege of attending the Forum four times, and each time I have been inspired and in awe of the social entrepreneurs I have met or seen. I am convinced that the social entrepreneurs who have been chosen to attend the Forum as either award winners or speakers are a special breed. They exhibit enormous passion and excitement for what they are doing and possess the kind of magnetism and persuasion abilities that make you want follow them into “battle” as either an employee, a volunteer, or a donor.
Phonon-assisted plasmon induced transparency in graphene nanostructures

The absorption due to phonon vibrations in graphene oxide quantum dots (GO-QDs) has been modified by localized plasmons induced by Ag nanoparticles (NPS). The interference of phonons and plasmons results in coherent interaction that leads to the formation of “dark states” and “coherent population trapping” related to Fano like effect. A quantum optical theory is used to qualitatively explain the differential absorption spectra measured using pump-probe spectroscopy demonstrating the formation of dark states.
An Organizing Framework for Specifying and Maintaining Catholic Identity in American Catholic Higher Education

All Catholic institutions are increasingly involved in discussions about what constitutes Catholic identity. It is a pressing question for schools, universities, hospitals, and social service agencies. As the debate proceeds on the possible implementation of formal norms for Catholic universities according to Ex Corde Ecclesiae, the question of Catholic identity becomes a most crucial for Catholic colleges and universities. Through a content analysis of literature on Catholic higher education, the author suggests a framework for specifying the content of Catholic identity. Within a structure of three major influences which are delineated in 18 categories, Catholic identity is described as a rich and multifaceted phenomenon.
Short-term succinic acid treatment mitigates cerebellar mitochondrial OXPHOS dysfunction, neurodegeneration and ataxia in a Purkinje-specific spinocerebellar ataxia type 1 (SCA1) mouse model

Mitochondrial dysfunction plays a significant role in neurodegenerative disease including ataxias and other movement disorders, particularly those marked by progressive degeneration in the cerebellum. In this study, we investigate the role of mitochondrial oxidative phosphorylation (OXPHOS) deficits in cerebellar tissue of a Purkinje cell-driven spinocerebellar ataxia type 1 (SCA1) mouse. Using RNA sequencing transcriptomics, OXPHOS complex assembly analysis and oxygen consumption assays, we report that in the presence of mutant polyglutamine-expanded ataxin-1, SCA1 mice display deficits in cerebellar OXPHOS complex I (NADH-coenzyme Q oxidoreductase). Complex I genes are upregulated at the time of symptom onset and upregulation persists into late stage disease; yet, functional assembly of complex I macromolecules are diminished and oxygen respiration through complex I is reduced. Acute treatment of postsymptomatic SCA1 mice with succinic acid, a complex II (succinate dehydrogenase) electron donor to bypass complex I dysfunction, ameliorated cerebellar OXPHOS dysfunction, reduced cerebellar pathology and improved motor behavior. Thus, exploration of mitochondrial dysfunction and its role in neurodegenerative ataxias, and warrants further investigation.
1 Mapping Bisexual Studies: Past and Present, and Implications for the Future

This chapter begins with an examination of bisexuality studies from the perspective of some prominent sex researchers from the late nineteenth century through the mid-twentieth century with a focus on how bisexuality was conceptualized by Richard von Krafft-Ebing, Havelock Ellis, Sigmund Freud, and Alfred Kinsey. Next, the chapter turns to a discussion and analysis of current research on bisexuality, identifying some recurring themes in the body of research such as bisexual identity development, life course changes in identity, attitudes about bisexuality, and debates about definitions and terms related to bisexuality in addition to what research into health and social disparities reveals about how bisexuality is framed and studied. This chapter then turns to an analysis of how bisexuality is taught within the academy, particularly in comparison to lesbian, gay, and queer studies. Finally, this chapter concludes with mapping the future of bisexuality studies with emphases on not only making bisexuality more visible but also focusing on physical and mental health aspects in addition to social and sexual justice issues.
Paulo Freire and Liberation Philosophy of Education

Freire’s project of critical literacy, which he initiated in 1946 when he was appointed director of the Department of Education and Culture of the Social Service in the state of Penambuco, Brazil, was an immediate overturning of the traditional classroom that, along with other vestiges of colonialism, has its roots in European authoritarian pedagogies that accentuate the dichotomy between the expertise of the master (instructor) and the ignorance of the novice (student). “By giving the student formulas to receive and store, we have not offered him the means for authentic thought” (Freire P, Education for critical consciousness. Seabury Press, New York, 1973, p. 38). In sum, Freire’s is a decolonial project intent on dismantling antidemocratic, anti-dialogic, and authoritarian schooling by initiating an entirely new project of liberation education within agricultural campesino communities and beyond.
Applications of Molecular Small-Animal Imaging in Cardiology

Cardiovascular disease (CVD) is a leading cause of death in both industrialized and developing countries, claiming more than 800,000 lives in the US and millions more in the rest of the world in recent years. Despite recent reduction in age-specific CVD mortality rate, increasing longevity, urbanization and industrialization has led to a rapid increase in the prevalence of CVD in both developed and developing nations. With surging health care costs the focus is shifting from treatment to prevention of disease as well as developing cost effective diagnostic and prognostic strategies. Conventional imaging modalities such as coronary angiography, echocardiography, myocardial perfusion imaging, computed tomography (CT) and magnetic resonance imaging (MRI), have been historically used to define structure and function as well as to monitor response to therapy, relying on the contrast provided by heterogeneity of anatomy, physiology and metabolism. As such, they provide valuable anatomical and physiological information about vasculature (e.g., extent of the disease, location, presence of calcification) and the myocardium (e.g., ejection fraction, wall thickening, dilatation, viability and cardiac output). However, traditional imaging modalities have limited use in detecting molecular and cellular events that determine the course of disease and its response to therapeutic interventions. Emerging molecular imaging modalities utilizing probes targeted at relevant molecular and cellular events can advance research on pathophysiology, allow early detection of disease, assist in the design of novel therapies, facilitate monitoring disease activity and response to therapy, and provide prognostic information.
Limitations in Piaget’s Equilibration Account

This time the ball flew to the ceiling and then paused at the point of bouncing. It seemed then to hang motionless in the air. For a long second it hung there— and throughout this time the ear awaited a rustling sound that never came, the ear stretched upwards for it, a sound that should have marked the friction of the ball with its shadow, the kiss of the ball’s light fur spinning against the ceiling. But silently it hung there, spinning slowly at the peak of its momentum, slowly as though turning round for the descent, hesitating against its own dark shadow, whispering against the ceiling a soundless kiss, suspended and yet still suspended for a moment of held beauty, breathless … (how long could it hang there? Would the rustle never be heard?) … until abruptly it dropped on its straight line gravitating downwards. (Sansom, p. 18)
Chest discomfort and abnormal chest radiograph.

A 67-year-old man presented to his physician because of intermittent chest discomfort of several months' duration. The patient stated that these symptoms seemed to be related to strenuous physical activity. Radiographic findings are shown below (Figures ​(Figures11–4).
Understanding the microenvironment of a PV module for better stress testing (Conference Presentation)

An understanding of the exposure environment of any material is necessary for the use of accelerated stress testing to evaluate different designs, materials, and configurations. For photovoltaic modules there is a wide range of environments and mounting conditions, each with a unique combination of temperature and humidity profiles. This is further compounded by differences in the microenvironment within a module, e.g. the humidity in the front EVA is not the same as the humidity in the backside EVA, and the presence of seasonal and diurnal changes in water content. We demonstrate how one can model the temperature and humidity environments of representative climates and use this to estimate the amount of moisture present in a PV module. To compare the relative degradation in different environments and to compare this to indoor testing, one must consider kinetically weighted parameters to characterize an environment. With some understanding of the kinetics, better choices for stress testing conditions can be made to minimize the uncertainty in correlating chamber results to the field allowing for better rank ordering of material and better service life prediction. This more general analysis highlights the fact that within reasonable limits a single humidity can represent a given climate. Thus, when a lower representative humidity is used, one can focus testing conditions on temperature effects and/or UV radiation. This can significantly simplify testing when very little is known about the humidity dependence of degradation processes.
Injuries of the Biceps Pulley System

The biceps pulley system (BPS) consists of capsulo-ligamentous fibres that stabilize the long head of the biceps (LHB) before the tendon enters into the proximal segment of the bony bicipital groove. It is formed by conjoining parts of the superior glenohumeral ligament, the coraco-humeral ligament and supporting fibres from the subscapularis and supraspinatus tendons. Additionally, it creates the junction part of the biceps-labral complex. Numerous reasons like chronic degeneration, repetitive microtrauma as well as an acute trauma can result in a lesion of this anatomical structure. Injuries of the BPS lead to instability of the LHB and result in significant anterior shoulder pain. They are often associated with tears of the rotator cuff and biceps tendon, SLAP lesions or internal antero-superior impingement. Several classification systems describe different groups of pulley lesions depending on the anatomical structures that are involved. In rare cases conservative treatment may result in pain relief using anti-inflammatory medication and physiotherapy, but most of the lesions require proper surgical treatment. According to the literature, repair of the BPS is not an acceptable management choice. In addition to arthroscopic or open repair of the concerned structures, tenotomy and tenodesis of the LHB both seem to be consistent treatment options for most shoulder surgeons resulting in significant pain relief.
Geographies of an Imperial Power: The British World, 1688–1815, by Jeremy Black

Jeremy Black sets out to ‘probe power in the eighteenth-century British world … by looking at the spatial character and understanding of this power’. He seeks to do so by showing how the ‘quest for...