Osmosis Jones
Tags: psychedelic, violence

Plot synopsis:
Frank Detorre is a widowed slovenly zookeeper at the Sucat Memorial Zoo in Rhode Island. Much to the frustration of his young daughter, Shane , he eats compulsively unhealthy and has minimal concern for germs or disease. While trying to eat a hard-boiled egg with mayonnaise and salt, it is stolen from him by a chimpanzee. He gets it back, but not before it falls into the filth of the chimp's habitat. When Shane is disgusted by him about to eat it he uses the "ten second rule" as a justification for the unsanitary act.Inside Frank's body, Osmosis "Ozzy" Jones, an agent of the Frank PD, is an adventure-seeking white blood cell with a good sense of humor. He is a rebel cop, frequently disobeying authority to do what he thinks is right. He is often mocked by his fellow cops due to his rebellious nature. He has been relocated to the mouth to fight against germs entering the body via ingestion after he induced Frank to vomit all over Shane's science and P. E. teacher, Mrs. Boyd at the school's science fair. This was considered a false alarm because he had been the only one to suspect an incoming pathological threat from the raw oyster Frank had eaten from one of the displays. After several newcomer germs, believed to be gingivitis, hijack a "squad car" in the mouth, Osmosis and another officer in an FPD helicopter, are pulled into the lungs by a massive yawn while in pursuit. After the germs evade capture and pass into "Immunity's" jurisdiction, Osmosis disobeys direct orders as he pursues the germ on foot and accidentally triggers a major cramp in Frank's leg.Meanwhile, Mayor Phlegmming is preparing for re-election, campaigning with the promise of more junk food. His reckless policies are largely responsible for Frank's deteriorating health, but his re-election hopes are complicated by the arrival of Thrax, a deadly virus that came with the hard-boiled egg. In an attempt to cover up the severity of the situation, Phlegmming "tells" Frank to take a cold-suppressant pill. The pill, Drixenol "Drix" Koldreliff, arrives in the body and covers Frank's infected throat with a disinfectant to soothe the irritation. Osmosis is assigned as Drix's partner, much to their mutual chagrin. Later on, an influenza virus tells Osmosis and Drix about Thrax's plot to masquerade as a common cold while at the same time plotting to kill Frank with a high fever. Osmosis and Drix confront Thrax in a club in one of Frank's zits, where Drix launches a grenade of medication at Thrax and his goons, popping the skin blemish, killing nearly all of Thrax's men, and seemingly ending the virus's siege. The pop of the zit further aggravates Mrs. Boyd, when Frank comes to apologize for his earlier action of vomiting on her at the science fair.Thrax survives the explosion and after killing off his remaining henchmen, launches a lone assault on Frank's hypothalamus gland (the portion of the brain that controls the temperature) by disabling its self-regulative capabilities. There, he uses his virus-infecting claw to destroy the protoplasmic barrier around the gland and takes a DNA bead. Soon after, the mayor's secretary, Leah Estrogen, discovers his sabotage and alerts security. Thrax manages to evade them, taking Leah hostage and escapes from the brain to the mouth. Meanwhile, the temperature continues to rise, causing chaos to break out all over the City of Frank. Frank is taken to the hospital under the influence of Thrax's attack. Ozzy and Drix rescue Leah and confront Thrax, who leaves Frank's mouth after causing confusion using pollen. Osmosis and Thrax fight on one of Shane's eyeballs and end up on Shane's false eyelashes after she blinks, which she was wearing atop her natural ones on her way to a hiking trip.During the fight, Thrax threatens to kill Shane, but Ozzy causes him to knock Shane's false eyelash into a vessel of alcohol below, where he dissolves. During this time, the situation becomes even more dangerous when the temperature hits 108 degrees Fahrenheit, causing Frank to go into cardiac arrest. Just as doctors give up, Frank is revived when Ozzy returns to his body with one of Shane's tears with the missing hypothalamus chromosome. Ozzy is reinstated into "Immunity" with full privileges, he and Drix are declared heroes with the Chief of Police giving Ozzy his job back. Having survived Thrax's attack, Frank has begun to improve his diet and personal hygiene.Meanwhile, Phlegmming has lost his position as mayor and is now a janitor in the bowels. He accidentally ejects himself from the body via the rectum by touching a button that is important and marked "DO NOT TOUCH!" which triggers Frank's farting.

Review: This movie gives a very imaginative way the body works to fight infection, as if the body was a city of people just like in the real world.
You may need to have some sort of knowledge about the body to get some of the puns and jokes, maybe not very young kids will get it, but they will like the animation...this movie is even good for adults.
The humor, while funny, is still very much what you'd expect from a Farelly Brothers movie that takes place inside a very sick man, so I wouldn't recommend it to little kids or the weak of stomach.
Although when you think about it the plot-line inside Frank's body (frank is played by Bill Murray with no shame in great form) is rather routine and for me was the only thing keeping this from being really good.Still, it might be a worthwhile movie, more for kids than adults, but it it watchable for all.
Only "There's Something About Mary" stands up against "Osmosis Jones," a film that jumps between live action and cartoon animation.
Osmosis Jones (voiced by Chris Rock) is one of those white blood cells who serves as a cop and must capture various villainous germs and viruses inside Frank.
After the virus, named Thrax (voiced by Laurence Fishburne), accumulates villainous help and starts on a plan to kill Frank in a record time of forty eight hours,  Osmosis must work with a cold pill named Drix (voiced by David Hyde Pierce), to stop this monstrously powerful germ before it's too late for Frank and his daughter.The movie has some very clever material-various parts of the body represent neighborhoods in the City of Frank.
Even adults will enjoy the live action humor, as well as the film's zest, energy, and irony.In a time when summer movies are at an all time low, "Osmosis Jones" is here to save they day.
How does the body work?I've always wanted to know exactly what goes on inside my body, and I must say I had a pretty fair idea thanks to my Biology class in school.Then I saw Osmosis Jones, which completely threw me off.The way Frank's body works and the cause/effect situations in this movie are hilarious!
The creative abilities of the creators of this movie seems endless even though it is limited to Frank's body.The characters are well drawn-out, and we even learn some of Jones' background (he lived in a certain area of the body and had hardly any education).
Even the rap and R&B music fit in and didn't sound too bad.All in all, Osmosis Jones is a great movie if you like animation (especially quick-action animated fighting scenes) and imaginative adventures such as these..
It was like a peculiar yet satisfying mix between the Incredible Journey, Toy Story, and Lethal Weapon or Rush Hour (the whole loose-cannon, loner cop with a new partner bit).I found the idea rather original: the human body is like a body of government, the cop is a white blood cell, the "president" was the cell whose will was that of the man (Bill Murray), the villain is a virus who hangs out in seedy areas of the body with shady characters, the bladder is a sort of train station/airport...
The live action combined with the animation was very creative and a great way to watch the movie.
And we travel inside Frank to see white blood cell policeman Osmosis Jones (Chris Rock) battle evil virus Thrax (Laurence Fishburne) with the help of Drix (David Hyde Pierce).Bill Murray looks awful as he gets sicker and sicker.
This is meant to be a family film.Now, the stuff I do like about it; the animation is great, it's very creative, (making the stomach the airport, the brain is city hall, the armpits are the steam room, I could go on)Laurence Fishburne was fantastic as Thrax.
It is remarkable that the writers and directors of this film felt it was appropriate to mesh a lot of highly original and creative material (the "metropolis" of a human body, complete down to every nuance of its function and translated into animation) with a main character setup that is now so trite (the fast-talking, annoying inner city cop with a chip on his shoulder who plays by his own rules and doesn't follow procedure, paired unwillingly with the practical straight man or some other stereotypical partner who will get on his nerves.) Chris Rock as the mouthy, wise-cracking cop from the wrong side of the tracks..
It's an animated film (in parts) about the internal workings of a man's body.The man is played by Bill Murray during the "live action" sequences.
These are intercut with animated sequences that involve cells and amoebas and organs and so on and so forth voiced by the likes of William Shatner, Chris Rock, Laurence Fishburne, David Hyde Pierce (Niles from "Frasier"), Kid Rock and Ron Howard.The cells are all animated cartoon characters who look, talk and act like humans.
They'd just see cartoon characters fighting, and be entertained and the whole knowledge of the body would almost have no effect on the kids.This movie felt like something an 8 year old would think if they were taught what we're usually taught in Grade 8 about cells and all that other stuff.I think the largest problem with this movie is that it was made to appeal to kids under 10, but it's directed at kids 13-17.
If you can get through the zit popping, puking and other disgusting characteristics of Bill Murray's character and pay attention to David Hyde Pierce and Chris Rock's back and forth then you are bound to leave the movie having had several good belly laughs.
This is a very cool live-action/animated movie starring Bill Murray as Frank Detorre, who after eating some bad food contracted a life-threatening virus.
In the movie, the internal organs of Frank's body is an animated world known as the City of Frank, and is where a policeman white blood cell named Osmosis Jones (Chris Rock) and a cold pill Frank took named Drix (David Hyde Pierce) attempt to stop the virus known as Drax (Lawrence Fishburne) from claiming Frank's life.I thought this movie is very clever and imaginative, putting the human body into a whole new perspective.
It makes your "insides" seem like an entire and adventurous different world, where in the film the white blood cells are law enforcement officers, lymph nodes are police stations, veins are highways, blood is water/lava, stomach is a bus station, a rowdy club is a pimple, and the germs and bacteria are the criminals.Marc Hyman wrote a fun, imaginative and adventurous script for the movie, cleverly depicting (in animation) how the human body fights infections and sickness.
And, the live-acting and voice casting were great - realistic and believable.As this movie is raged PG, there is also quite a bit of bodily humor, puns and jokes, especially involving digestion, going to the restroom, passing gas, popping pimples from the face, food in the mouth..
PROS: -Creative Premise and Environment (some of the body part/city comparisons were brilliant) -Good Comedy(includes several HILARIOUS Sight Gags.) -Cool Villain -Decent Animation CONS: -The Parts with Bill Murray on camera can sometimes drag a touch.
In a very creative and funny way, the producers teach us a lot about our body through the adventure of Osmose Jones, a white blood cell, and Drix, a cold pill.
David Hyde Pierce was also great as the Cold Pill named Drix.The animation is really cool, and I guess you could sort of say it's one of the last good animated movies made, seeing as the world has been taken over with CGI (Which is not necessarily a bad thing...
The plot of the story is extremely well thought of and in hindsight i can understand why it is made by the Farrelly brothers, they have a reputation of making offbeat and skew movies, this one would fall into those categories just from the plot idea.The acting is good, Bill Murray pulls off a very believing father who doesn't give a hoot about germs and disgusting food habits, and therefore his body becomes the host of a very nasty virus named Thrax, and then the movie takes off.For those 90 minutes you will be very entertained and at some times you will close your eyes in disgust while your children will scream and laugh, i wont tell you where these things happen but rest assured, THEY WILL!
:)All in all this is a great movie and the voice cast for the main roles fits perfectly, although i have a little trouble with David Hyde Pierce lending his voice to a wannabe-hero-medicine-cold-reliever just from remembering him from Frasier, but after a little while you could not imagine anyone else giving voice.Give this film a chance in the DVD player, you will not be disappointed if you like : Original Plot idea.
I would recommend this movie to EVERYONE!It has everything for everyone:Bill Murray: (One of his funniest movies--and thats saying a lot!) Great Animation: (More than just eye candy, it puts a hilarious spin on the inside of our bodies, and funny ideas about whats going on in there!) Chris Rock: (Great how well he fit this part) William Shatner: (Perfectly Cast as the Mayor of Bill Murrays Brain) Molly Shannon: (Plays great with Bill Murray as his poor daughters teacher) BUFFALO WINGS!!
Bill Murray, who plays Frank, fans might be disappointed that all he does is make funny faces, say stupid things and be  gross to facilitate the plot but the real comedy is in Chris Rock's character  Osmosis Jones and his partner played by Fraiser's David Hyde Pierce.
"Osmosis Jones" is a very funny, entertaining and clever film brought by the Farrelly brothers, creators of comedies like "Dumb and Dumber", "There's Something About Mary" and "Me, Myself & Irene".
This last one is the main part of the film, where we find our white blood cell cop "Osmosis Jones" (Chris Rock), followed by his partner Drix (David Hyde Pierce), a cold tablet, in order to prevent the body from the attack of the evil and powerful virus Thrax (Lawrence Fishburne).
There's a major disconnect between the live action sequences with Frank (Bill Murray) in the real world (which make up perhaps 1/3 of the movie) and theanimated sequences of what's going on inside his body.
For me, this very cartoony anthropomorphic world of his internal organisms (the animation design reminds me of the Simpsons a little bit) just cannot possibly exist at all in the real world...yet we are supposed to believe that Frank's white blood cells look like Smurf/Bart Simpson hybrids and sound like Chris Rock...it was just impossible for me to suspend my disbelief as the film cuts back and forth between these two completely different universes.
The audience feels no sympathy towards Murray and that is the fatal flaw of the film.And really, I expected more of Rock...there are a couple of scenes where it looks like he was able to improvise and do his thing but for the most part the filmmakers keep him on a pretty short leash and stick to the script, and I really think that an opportunity may have been missed there.
How it functions by having a whole community run by a mayor (William Shatner) and a police force of white blood cells and a lot of real-life city stuff showcased a lot of creative effort was put into it.It centers on a white blood cells Osmosis Jones (Chris Rock) who is that kind of cop who does things his own way and the others at the police station do not approve of his ways, but he is later assigned to a new case with a partner to keep him on track, a cold pill named Drix (David Hyde Pierce).
I'll give him more credit for that.The live-action segments is the movie's biggest drawbacks with an unlikable main character and lowbrow humour as you would expect from the farelly brothers, and frankly (no pun intented) the animated segments aren't perfect and the transitions between the two don't always work.But overall Osmosis I found Osmosis Jones enjoyable, but flawed.
Chris Rock plays a lively white blood cell cop who responds when Frank eats a hard boiled egg that's home to a deadly virus, and runs all about the City Of Frank chasing it down, joined by a robotic cherry flavoured Cold Pill (David Hyde Pierce).
Good Animation, Nicely Voiced and With An Interesting Story, Osmosis Jones is a mediocre unique type of a animated movie which is good for time-pass and can entertain you with its mind-boggling but unique and satirical story about the human body along with nice Voice acting by Chris Rock(who was very good) and Lawrence Fishburne and decent effort from the directors Bobby and Peter Farrelly.The Story is quite unique about the body of Frank Detorre and what takes place in his body which is full of oily and harmful junk food which he consumes on a daily basis, and how the protective cells in the human body fight to destroy the bacteria and virus's which come into the body through the food.
The Main Character is Osmosis Jones(Chris Rock), who is a cop cell who always manages to run into trouble and harm Frank's body and he tries to become famous by defeating the harmful virus which wants to kill Frank with his partner Thrax(Fishburne).The Voice acting by the lead actors are very good and they have successfully synchronised their voices with their characters and helped in making the characters look very real!
Also, I liked the characters, Ozzy and Drix are likable and what they get up to is intriguing, fun and often unpredictable, Thrax is a great villain and the voice acting from Chris Rock, Laurence Fishburne, David Hyde Pierce, William Shatner and Bill Murray is top notch.
At the same time the mayor of Frank is doing what he can to cover it up as just a brief cold to avoid panic as the election is coming up.Osmosis Jones is a clever little movie combining animation and real life to tell the story.
This was a very clever idea, that effectively shows a live-action sequence, then presents the interior of a character's (Frank - Bill Murray) body in animation.
Our hero is a white blood cell named Osmosis Jones (Voiced well by Chris Rock, far more entertaining here than in every other movie role I've seen him in), who has to stop the evil virus before it's too late.Here is the unusual film that is actual more childish and cartoony during the live action Bill Murray scenes (which feature a fight with a monkey, an exploding zit, and flatulence) and witty and adult in the animated scenes.
Part live action, part animation, it's a spin on buddy pictures that takes place in zookeeper Bill Murray's body, where a rogue virus (the voice of Laurence Fishburne) plots to kill Murray while a disgraced police cell (no pun intended) voiced by Chris Rock teams with a cold pill (the voice of David Hyde Pierce) to defeat him.
Somewhere between "Yuck!" and "Yuk-Yuk!" falls "Osmosis Jones," a puzzling but memorable departure for the Farrelly brothers, whose previous forays into bodily functions have heretofore been WAAAY beyond PG and animated only in the sense that they were vividly and hilariously grotesque.The title character is voiced with patent hip by Chris Rock, who brings life to a white blood cell/loose cannon cop on the trail of a particularly nasty baddy named Thrax (Lawrence Fishburne).
It's about an ambitious, but sometimes a little clumsy white blood cell cop named Osmosis Jones [voiced by Chris Rock] who teams up with a wise-cracking cold tablet named Drix [voiced by David Hyde Pierce] to protect the human they live inside [Bill Murray] from an evil virus named Thrax that his making the body sick.
OSMOSIS JONES is a funny, well-animated, creative, action-packed, and entertaining family film that should please both kids and adults.
Clever enough to keep you watching, although bits of the plot were predictable and pedestrian Bill Murray was as usual terrifically watchable, and the cartoon animation was fun.The press reviews have been poor for this one, but as usual they miss the boat when it comes to kid's movies -my 8-1/2 year old daughter loved it, and still talks about it days later.
I missed it in thearters,and i forgot to rent it,but recently i saw it on a movie channel.The characters are funny and imaginative,and the animation is colourful.It all starts in a zoo,where Frank(Bill Murray) eats an egg that's been in a monkeys mouth(yes,i thought it was gross too ><).Now the animation part comes in.A white blood cell cop,Osmosis Jones(Chris Rock),and "that annoying smart guy" cold pill Drix(David Hyde Pierce)have to get rid of the virus from the egg,Thrax(Laurence Fishburne).Sounds complicated?It's not.It's just a buddy cop movie taking place inside "The City of Frank".The live action looks funny,but it is gross and just horrible.How?Hmm...let me see..Frank barfs on his daughters teacher,and his zit pops.Just pops outta nowhere,and it lands on the teacher(she must live a terrible life XD).And it's not funny!The "jokes" that were attempted never made me laugh.But if you have a young kid who likes toliet humour,knock yourself out.
That said, "Osmosis Jones" is a pretty interesting movie in that it manages to follow two separate story lines (filmed in different medium: live action and animation) fairly well.
Moving to the animated story line, Osmosis Jones (voiced by Chris Rock) is a white-blood-cell that discovers the virus and must stop him from killing Frank, and all the people (cells) in Frank's body.I found myself interested in each story line, and the transfers between live action and animation kept the movie exciting.
The way that Bill Murray lives his life in this movie is downright wrong and gross but can be pretty funny watching him go by his ten second rule in eating things.