News Finding: Tissues from equine cadaver ligaments up to 72 hours of post-mortem: a promising reservoir of stem cells.
Paper Finding: The present work is the first, in both animal and human, to show that tissues harvested from cadaveric ligaments up to 72 hours postmortem represent an available reservoir of specific stem cell populations.
News Context: Tissues from equine cadaver ligaments up to 72 hours of post-mortem: a promising reservoir of stem cells. Phase contrast microscopy revealed that cells with fibroblast-like appearance were predominant in the culture. Differentiation assays proved that EC-MSCs are able to differentiate towards mesodermal lineages (osteogenic, adipogenic, chondrogenic).
Paper Context: Taking these observations into account, fundamental and clinical research studies are now required to investigate whether MSCs isolated from equine cadavers are suitable, abundant, and readily available to be used in future clinical applications. The present work is the first, in both animal and human, to show that tissues harvested from cadaveric ligaments up to 72 hours postmortem represent an available reservoir of specific stem cell populations. SLs were confirmed free of any damage following examination of the tissues both macroscopically and microscopically.