News Finding: Both conditions are also present in individuals with a mutated CHD8 gene.
Paper Finding: We did not identify enrichment with genes downregulated in postmortem ASD cortex.
News Context: "This is critical to understanding the biology of disorders like autism." Both conditions are also present in individuals with a mutated CHD8 gene. New implications for early and lifelong brain development
  
  Analysis of data from mouse brains reveals that CHD8 gene expression peaks during the early stages of brain development.
Paper Context: Finally, we observed enrichment (P = 0.012) between DE upregulated genes and genes associated with immune response that were upregulated in cortex from postmortem ASD brains 24 . We did not identify enrichment with genes downregulated in postmortem ASD cortex. We observed consistent enrichment among up-and downregulated DE genes in Chd8 +/del5 forebrain and up-and downregulated DE genes identified in previous studies (Fig.