News Finding: "Results suggest that the KFRE could be incorporated into the clinical care of children with CKD to aid in anticipatory guidance, timing of referral for transplant evaluation, and planning for dialysis access," the authors write.
Paper Finding: Results suggest that the KFRE could be incorporated into the clinical care of children with CKD to aid in anticipatory guidance, timing of referral for transplant evaluation, and planning for dialysis access.
News Context: The researchers found that over a median observation time of 3.8 years, 144 participants (23.9 percent) developed ESRD within five years of enrollment. The predictive abilities of the four- and eight-variable KFRE scores were similar for discrimination of ESRD risk (C statistics of 0.90, 0.86, and 0.81 for the one-, two-, and five-year four-variable KFRE risk scores, respectively; 0.91, 0.87, and 0.82, respectively, for the eight-variable KFRE scores). "Results suggest that the KFRE could be incorporated into the clinical care of children with CKD to aid in anticipatory guidance, timing of referral for transplant evaluation, and planning for dialysis access," the authors write.
Paper Context: CONCLUSIONS AND RELEVANCE The KFRE is a simple tool that provides excellent discrimination of the risk of ESRD. Results suggest that the KFRE could be incorporated into the clinical care of children with CKD to aid in anticipatory guidance, timing of referral for transplant evaluation, and planning for dialysis access. Improved estimation of when a child with CKD will experience progression to ESRD has several potentially valuable applications.