News Finding: It can remain inside the body, reproducing, for decades.
Paper Finding: The non-linear SVM is used in QDREC as the default classifier because it exhibited less parameter sensitivity and more reliable convergence than the linear SVM.
News Context: The software is now available for parasitologists, biologists and other drug developers around the world to use -- free of charge -- in the quest to find a cure for schistosomiasis. It can remain inside the body, reproducing, for decades. While a drug, called praziquantel, does exist to treat the disease, Singh pointed out, using a single drug to treat millions of people across a large area over decades carries a high risk of the parasite building resistance.
Paper Context: Classification accuracy and the mean and standard deviation of NRMSE, correlation and log 10 (P-value) are shown for 12 drugs (atorvastatin, fluvastatin, lovastatin, pravastatin, rosuvastatin, simvastatin, closantel, ibandronate, K11777, niclosamide, praziquantel and sorafenib). The non-linear SVM is used in QDREC as the default classifier because it exhibited less parameter sensitivity and more reliable convergence than the linear SVM. All results are for two-stage classification using parasite and control feature vector tuples.