News Finding: KCNA2; ; 13868; epileptic encephalopathy.; Monoallelic; Loss of function; 
Paper Finding: Screening a pilot cohort of 33 patients, we identified mutations in known epilepsy-related genes in 16 cases 17 .
News Context: KCNA2; ; 13868; epileptic encephalopathy.; Monoallelic; Loss of function; 
Paper Context: Therefore, potassium channel genes represent interesting candidates for neurodevelopmental disorders. Screening a pilot cohort of 33 patients, we identified mutations in known epilepsy-related genes in 16 cases 17 . We evaluated the remaining 17 cases for mutations in candidate genes (Supplementary Note), which led to the detection of a heterozygous de novo mutation in KCNA2, c.1214C>T (encoding p.Pro405Leu), affecting the highly conserved pore domain of the voltage-gated potassium channel K V 1.2 (NM_004974, CCDS827).