News Finding: Double-blind placebo controlled #tACS trial for treatment of major depressive disorder. Response rates: 10Hz-tACS:  78% versus 40Hz-tACS: 30%, versus sham-tACS: 20%. Significant suppression of left frontal alpha. Work by Morgan Alexander &amp; @username. 
Paper Finding: Concurrently, we found a significant reduction in alpha power over the left frontal regions in EEG after completion of the intervention for the group that received per-protocol 10 Hz-tACS (n = 26, p < 0.05).
News Context: Double-blind placebo controlled #tACS trial for treatment of major depressive disorder. Response rates: 10Hz-tACS:  78% versus 40Hz-tACS: 30%, versus sham-tACS: 20%. Significant suppression of left frontal alpha. Work by Morgan Alexander &amp; @username. 
Paper Context: For the primary outcome, we did not observe a significant interaction between treatment condition (10 Hz-tACS, 40 Hz-tACS, sham) and session (baseline to 4 weeks after completion of treatment); however, exploratory analyses show that 2 weeks after completion of the intervention, the 10 Hz-tACS group had more responders (MADRS and HDRS) compared with 40 HztACS and sham groups (n = 30, p = 0.026). Concurrently, we found a significant reduction in alpha power over the left frontal regions in EEG after completion of the intervention for the group that received per-protocol 10 Hz-tACS (n = 26, p < 0.05). Our data suggest that targeting oscillations with tACS has potential as a therapeutic intervention for treatment of MDD.