News Finding: It show that there are many forms of Bd and that the fungus can mutate quickly, changing from a mild version into a deadly version almost overnight.
Paper Finding: Combining molecular modeling, combinatorial chemistry, and high-throughput screening has the potential to develop chemicals with reduced resistance risk (37) .
News Context: Unfortunately, this research is simply bad news for those amphibian populations. It show that there are many forms of Bd and that the fungus can mutate quickly, changing from a mild version into a deadly version almost overnight. Short of developing some sort of cure and delivering it to populations of amphibians, it may simply be up to those amphibians to survive by themselves.
Paper Context: This situation parallels the situation for antibiotics. Combining molecular modeling, combinatorial chemistry, and high-throughput screening has the potential to develop chemicals with reduced resistance risk (37) . Where target-site mutations confer high levels of resistance, lower doses of antifungals should be favored (40, 41) .