News Finding: The team found no animals with APAF1 from both parents among the 758 animals tested.
Paper Finding: Among all animals within the validation set, 246 unique haplotypes existed within the HH1 interval, as well as 323 heterozygous haplotype combinations.
News Context: But if it inherits copies of the mutation from both parents, the combination is fatal. The team found no animals with APAF1 from both parents among the 758 animals tested. Commercial testing of more than 246,000 Holsteins showed the same results.
Paper Context: These haplotypes are much shorter and different than those originally defined by the 75-marker window (derived from the 54,001 chip) spanning 7.1 Mbp that was used to find HH1. Among all animals within the validation set, 246 unique haplotypes existed within the HH1 interval, as well as 323 heterozygous haplotype combinations. Additionally, animals possessing "haplotype 32" (n = 11) had a small region of 40 markers in a 1-Mb region within the HH1 interval that was expected to be equivalent to haplotype 12 because haplotype 32 is a recombinant haplotype.