News Finding: Tissues from equine cadaver ligaments up to 72 hours of post-mortem: a promising reservoir of stem cells.
Paper Finding: This study demonstrated that a viable stem cell population can be isolated and expanded from equine cadaver ligaments up to 72 hours post-mortem.
News Context: Tissues from equine cadaver ligaments up to 72 hours of post-mortem: a promising reservoir of stem cells. Phase contrast microscopy revealed that cells with fibroblast-like appearance were predominant in the culture. Differentiation assays proved that EC-MSCs are able to differentiate towards mesodermal lineages (osteogenic, adipogenic, chondrogenic).
Paper Context: These observations are also in accordance with another study on ultrastructural changes of MSCs during neuronal induction . This study demonstrated that a viable stem cell population can be isolated and expanded from equine cadaver ligaments up to 72 hours post-mortem. Differentiation assays, flow cytometry, immunofluorescence and TEM analyses confirmed the stemness of these cells.