News Finding: This treatment is to be applied.
Paper Finding: Clinical genetic studies and correlation with functional investigations from additional patients with further mutations are needed to confirm this genotypephenotype relationship.
News Context: For patients whose potassium flows are too high, there is an immediate treatment option in the form of 4-aminopyridine, an approved drug which specifically blocks the relevant ion channel. This treatment is to be applied. The researchers and doctors hope it will lead to a reduction of seizures and improve mental abilities.
Paper Context: This may suggest that different pathomechanisms underlie distinctive clinical symptoms. Clinical genetic studies and correlation with functional investigations from additional patients with further mutations are needed to confirm this genotypephenotype relationship. The panel used to screen the pilot cohort of 33 patients (including the index patient) comprised 485 known and putative epilepsy-related genes (Supplementary Table 1) .