DOI,instance_id,News Finding,Paper Finding,News Context,Paper Context,scores,field,split,final_score,source,News URL 10.1145/2702123.2702397,Computer_Science_1,"The final analysis shows that the mixed-reality game improved learning by almost five times more than the screen-only alternatives, both in the mouse-controlled and physically controlled conditions.",The overall improvement from pre to post was 11.3 % in the mixed-reality conditions and 2.4 % in the virtual conditions.,"A game that combined real-world experiments with interactions on a computer tablet improved learning by almost five times more than screen-only alternatives. The final analysis shows that the mixed-reality game improved learning by almost five times more than the screen-only alternatives, both in the mouse-controlled and physically controlled conditions. Not only that, but students enjoyed the game more in the mixed-reality conditions.","The overall results (including both the prediction and explanation items) indicated that there was a significant effect of media-type (F(1,91)=8.2, p<0.01, d=0.37). The overall improvement from pre to post was 11.3 % in the mixed-reality conditions and 2.4 % in the virtual conditions. Thus, the mixed-reality game improved learning by 4.8 times compared to the screen-only alternatives.","[3.0, 4.0, 3.0, 4.0, 4.0]",Computer_Science,test,3.6,news,http://www.theepochtimes.com/n3/1354229-why-tablets-cant-replace-real-world-schools/ 10.1126/science.aao4408,Computer_Science_10,"They found that the refugees' eventual economic self-sufficiency depended on a combination of their individual characteristics, such as education level and knowledge of English, and where they were resettled within the country.",Various mapping functions can be used.,"They found that the refugees' eventual economic self-sufficiency depended on a combination of their individual characteristics, such as education level and knowledge of English, and where they were resettled within the country. It turned out that refugees with particular backgrounds or skills achieved better outcomes in some locations than others. The algorithm assigned placements for refugees that they project would increase their chances of finding employment by roughly 40 to 70 percent compared with how the refugees actually fared, according to the new study, published in Science.","A separate model was fit for subgroups of refugees assigned to each location, thus yielding different models for each location and allowing for the discovery of refugee/location synergies. Various mapping functions can be used. Our preferred case-level metric was the predicted probability that at least one refugee in the case would find employment at the location in question.","[1.0, 1.0, 1.0, 1.0, 1.0]",Computer_Science,test,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/ycYLqg96qto/ 10.1126/science.aao4408,Computer_Science_101,"The algorithm assigned placements for refugees that they project would increase their chances of finding employment by roughly 40 to 70 percent compared with how the refugees actually fared, according to the new study in Science.","Our approach led to gains of roughly 40 to 70%, on average, in refugees' employment outcomes relative to current assignment practices.","In 2016 alone, about 65.6 million people were forced to flee their homes. The algorithm assigned placements for refugees that they project would increase their chances of finding employment by roughly 40 to 70 percent compared with how the refugees actually fared, according to the new study in Science. The group, from Stanford and ETH Zurich, says the algorithm, which could be implemented at virtually no cost, could help resource-constrained governments and resettlement agencies find the best places for refugees to relocate.","Our approach led to gains of roughly 40 to 70%, on average, in refugees' employment outcomes relative to current assignment practices. This approach can provide governments with a practical and cost-efficient policy tool that can be immediately implemented within existing institutional structures. It is also one of the most consequential in maximizing refugees' economic integration and self-sufficiency as a first step toward a more comprehensive integration into society (7-9).","[5.0, 5.0, 5.0, 5.0]",Computer_Science,test,5.0,news,http://www.futurity.org/refugee-resettlement-algorithm-1658522-2/ 10.1126/science.aao4408,Computer_Science_106,"They found that the refugees' eventual economic self-sufficiency depended on a combination of their individual characteristics, such as education level and knowledge of English, and where they were resettled within the country.","In addition, refugees with certain characteristics, such as language and educational skills, are more likely to succeed economically regardless of the resettlement location to which they are sent (Fig.","They found that the refugees' eventual economic self-sufficiency depended on a combination of their individual characteristics, such as education level and knowledge of English, and where they were resettled within the country. It turned out that refugees with particular backgrounds or skills achieved better outcomes in some locations than others. The algorithm assigned placements for refugees that they project would increase their chances of finding employment by roughly 40 to 70 percent compared with how the refugees actually fared, according to the new study, published in Science.","It is also one of the most consequential in maximizing refugees' economic integration and self-sufficiency as a first step toward a more comprehensive integration into society (7) (8) (9) . In addition, refugees with certain characteristics, such as language and educational skills, are more likely to succeed economically regardless of the resettlement location to which they are sent (Fig. Finally, the expected employment returns associated with personal characteristics can vary across different resettlement locations (Fig.","[5.0, 5.0, 4.0, 5.0]",Computer_Science,test,4.75,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/ycYLqg96qto/ 10.1145/2702123.2702397,Computer_Science_109,"Not only that, but students enjoyed the game more in the mixed-reality conditions.","On the other hand, integrating simple physical controls such as shaking the tablet has little effect.","The final analysis shows that the mixed-reality game improved learning by almost five times more than the screen-only alternatives, both in the mouse-controlled and physically controlled conditions. Not only that, but students enjoyed the game more in the mixed-reality conditions. They also determined that simple physical controls like shaking the tablet or pushing the earthquake button did little to improve either learning or enjoyment of the game.","We provided evidence that experiencing physical phenomena accompanied by interactive feedback via depth camera sensing in the real world improves learning (by approximately 5 times compared to a solely screen-based environment), while also enhancing enjoyment significantly. On the other hand, integrating simple physical controls such as shaking the tablet has little effect. Thus, mixed-reality games that support physical observation in the real world have a great potential to enhance learning and enjoyment for young children.","[3.0, 1.0, 1.0]",Computer_Science,test,1.6666666666666667,news,http://www.theepochtimes.com/n3/1354229-why-tablets-cant-replace-real-world-schools/ 10.1126/science.aao4408,Computer_Science_11,"The algorithm assigned placements for refugees that they project would increase their chances of finding employment by roughly 40 to 70 percent compared with how the refugees actually fared, according to the new study in Science.",Various mapping functions can be used.,"In 2016 alone, about 65.6 million people were forced to flee their homes. The algorithm assigned placements for refugees that they project would increase their chances of finding employment by roughly 40 to 70 percent compared with how the refugees actually fared, according to the new study in Science. The group, from Stanford and ETH Zurich, says the algorithm, which could be implemented at virtually no cost, could help resource-constrained governments and resettlement agencies find the best places for refugees to relocate.","A separate model was fit for subgroups of refugees assigned to each location, thus yielding different models for each location and allowing for the discovery of refugee/location synergies. Various mapping functions can be used. Our preferred case-level metric was the predicted probability that at least one refugee in the case would find employment at the location in question.","[1.0, 1.0, 1.0, 1.0, 1.0]",Computer_Science,test,1.0,news,http://www.futurity.org/refugee-resettlement-algorithm-1658522-2/ 10.1126/science.aao4408,Computer_Science_111,They predicted the employment rate would have been 73 percent higher among asylum seekers who arrived in 2013 if they had been assigned to the places the algorithm identified as optimal.,Various mapping functions can be used.,"The group found that if the algorithm had selected locations for refugees' resettlement, the average employment rate among those refugees would have been roughly 41 percent higher. They predicted the employment rate would have been 73 percent higher among asylum seekers who arrived in 2013 if they had been assigned to the places the algorithm identified as optimal. In Vaud, employment prospects are higher for anyone who speaks French.","A separate model was fit for subgroups of refugees assigned to each location, thus yielding different models for each location and allowing for the discovery of refugee/location synergies. Various mapping functions can be used. Our preferred case-level metric was the predicted probability that at least one refugee in the case would find employment at the location in question.","[1.0, 1.0, 4.0, 1.0]",Computer_Science,test,1.0,news,http://www.futurity.org/refugee-resettlement-algorithm-1658522-2/ 10.1145/2702123.2702397,Computer_Science_112,"[related] The final analysis shows that the mixed-reality game improved learning by almost five times more than the screen-only alternatives, both in the mouse-controlled and physically controlled conditions.","These results show that mixed-reality led to more learning than screen only, for both the mousecontrol and physical-control conditions ( Figure 10 ).","[related] The final analysis shows that the mixed-reality game improved learning by almost five times more than the screen-only alternatives, both in the mouse-controlled and physically controlled conditions. Not only that, but students enjoyed the game more in the mixed-reality conditions. They also determined that simple physical controls like shaking the tablet or pushing the earthquake button did little to improve either learning or enjoyment of the game.","There was no effect of control type and no interaction effects. These results show that mixed-reality led to more learning than screen only, for both the mousecontrol and physical-control conditions ( Figure 10 ). We can consider what choice improves learning most over a typical virtual, mouse-control game (#1 in Figure 10 ).","[4.0, 4.0, 5.0, 5.0]",Computer_Science,test,4.5,news,http://www.futurity.org/tablets-real-world-learning-917682/ 10.1145/2702123.2702397,Computer_Science_118,"""Mixed-reality games that support physical observation in the real world have a great potential to enhance learning and enjoyment for young children,"" the researchers say.","showed that children used more meaningful gestures while explaining their predictions when they observed physical blocks in a mixed-reality game, compared to a screen-only version of the same game.","They also determined that simple physical controls like shaking the tablet or pushing the earthquake button did little to improve either learning or enjoyment of the game. ""Mixed-reality games that support physical observation in the real world have a great potential to enhance learning and enjoyment for young children,"" the researchers say. They plan to extend their mixed-reality game to different content areas to create a new educational system that bridges the advantages of physical and virtual worlds to improve children's science learning, understanding and enjoyment in a collaborative way.","Experiencing physical phenomena in real life may help people perceive and mentally visualize the physical objects in 3D in their minds, make connections with objects they are familiar with, and as a result remember the concepts better. showed that children used more meaningful gestures while explaining their predictions when they observed physical blocks in a mixed-reality game, compared to a screen-only version of the same game. This result suggests that children may be having more meaningful mental visualizations (demonstrated by the gestures they use) when they interact with 3D objects .","[3.0, 2.0, 3.0, 2.0]",Computer_Science,test,2.5,news,http://www.theepochtimes.com/n3/1354229-why-tablets-cant-replace-real-world-schools/ 10.1126/science.aao4408,Computer_Science_125,"The group found that if the algorithm had selected locations for refugees' resettlement, the average employment rate among those refugees would have been roughly 41 percent higher.","Finally, the expected employment returns associated with personal characteristics can vary across different resettlement locations (Fig.","The group, from Stanford and ETH Zurich, says the algorithm, which could be implemented at virtually no cost, could help resource-constrained governments and resettlement agencies find the best places for refugees to relocate. The group found that if the algorithm had selected locations for refugees' resettlement, the average employment rate among those refugees would have been roughly 41 percent higher. They predicted the employment rate would have been 73 percent higher among asylum seekers who arrived in 2013 if they had been assigned to the places the algorithm identified as optimal.","In addition, refugees with certain characteristics, such as language and educational skills, are more likely to succeed economically regardless of the resettlement location to which they are sent (Fig. Finally, the expected employment returns associated with personal characteristics can vary across different resettlement locations (Fig. This indicates that there are synergies between places and people; certain characteristics will make a refugee a better match for a particular location.","[4.0, 3.0, 4.0, 2.0]",Computer_Science,test,3.25,news,http://www.futurity.org/refugee-resettlement-algorithm-1658522-2/ 10.1126/science.aao4408,Computer_Science_127,It turned out that refugees with particular backgrounds or skills achieved better outcomes in some locations than others.,This indicates that there are synergies between places and people; certain characteristics will make a refugee a better match for a particular location.,"They found that the refugees' eventual economic self-sufficiency depended on a combination of their individual characteristics, such as education level and knowledge of English, and where they were resettled within the country. It turned out that refugees with particular backgrounds or skills achieved better outcomes in some locations than others. In 2016 alone, about 65.6 million people were forced to flee their homes.","Finally, the expected employment returns associated with personal characteristics can vary across different resettlement locations (Fig. This indicates that there are synergies between places and people; certain characteristics will make a refugee a better match for a particular location. In Switzerland, for example, we find that the ability to speak French (i.e., among French-speaking African refugees) results in a larger payoff for refugees assigned to Frenchspeaking cantons than for those assigned to German-speaking cantons ( fig.","[5.0, 4.0, 5.0, 4.0, 4.0]",Computer_Science,test,4.4,news,http://www.futurity.org/refugee-resettlement-algorithm-1658522-2/ 10.1126/science.aao4408,Computer_Science_129,It turned out that refugees with particular backgrounds or skills achieved better outcomes in some locations than others.,"In addition, refugees with certain characteristics, such as language and educational skills, are more likely to succeed economically regardless of the resettlement location to which they are sent (Fig.","They found that the refugees' eventual economic self-sufficiency depended on a combination of their individual characteristics, such as education level and knowledge of English, and where they were resettled within the country. It turned out that refugees with particular backgrounds or skills achieved better outcomes in some locations than others. In 2016 alone, about 65.6 million people were forced to flee their homes.","It is also one of the most consequential in maximizing refugees' economic integration and self-sufficiency as a first step toward a more comprehensive integration into society (7-9). In addition, refugees with certain characteristics, such as language and educational skills, are more likely to succeed economically regardless of the resettlement location to which they are sent (Fig. Finally, the expected employment returns associated with personal characteristics can vary across different resettlement locations (Fig.","[4.0, 3.0, 2.0, 5.0]",Computer_Science,test,3.5,news,http://www.futurity.org/refugee-resettlement-algorithm-1658522-2/ 10.1145/2702123.2702397,Computer_Science_130,"""Mixed-reality games that support physical observation in the real world have a great potential to enhance learning and enjoyment for young children,"" the researchers say.",The overall improvement from pre to post was 11.3 % in the mixed-reality conditions and 2.4 % in the virtual conditions.,"They also determined that simple physical controls like shaking the tablet or pushing the earthquake button did little to improve either learning or enjoyment of the game. ""Mixed-reality games that support physical observation in the real world have a great potential to enhance learning and enjoyment for young children,"" the researchers say. They plan to extend their mixed-reality game to different content areas to create a new educational system that bridges the advantages of physical and virtual worlds to improve children's science learning, understanding and enjoyment in a collaborative way.","The overall results (including both the prediction and explanation items) indicated that there was a significant effect of media-type (F(1,91)=8.2, p<0.01, d=0.37). The overall improvement from pre to post was 11.3 % in the mixed-reality conditions and 2.4 % in the virtual conditions. Thus, the mixed-reality game improved learning by 4.8 times compared to the screen-only alternatives.","[4.0, 2.0, 1.0, 2.0, 2.0]",Computer_Science,test,2.2,news,http://www.theepochtimes.com/n3/1354229-why-tablets-cant-replace-real-world-schools/ 10.1126/science.aao4408,Computer_Science_138,"They found that the refugees' eventual economic self-sufficiency depended on a combination of their individual characteristics, such as education level and knowledge of English, and where they were resettled within the country.","Our approach led to gains of roughly 40 to 70%, on average, in refugees' employment outcomes relative to current assignment practices.","They found that the refugees' eventual economic self-sufficiency depended on a combination of their individual characteristics, such as education level and knowledge of English, and where they were resettled within the country. It turned out that refugees with particular backgrounds or skills achieved better outcomes in some locations than others. The algorithm assigned placements for refugees that they project would increase their chances of finding employment by roughly 40 to 70 percent compared with how the refugees actually fared, according to the new study, published in Science.","Our approach led to gains of roughly 40 to 70%, on average, in refugees' employment outcomes relative to current assignment practices. This approach can provide governments with a practical and cost-efficient policy tool that can be immediately implemented within existing institutional structures. It is also one of the most consequential in maximizing refugees' economic integration and self-sufficiency as a first step toward a more comprehensive integration into society (7-9).","[2.0, 3.0, 4.0, 3.0]",Computer_Science,test,3.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/ycYLqg96qto/ 10.1145/2702123.2702397,Computer_Science_144,"Not only that, but students enjoyed the game more in the mixed-reality conditions.",The overall improvement from pre to post was 11.3 % in the mixed-reality conditions and 2.4 % in the virtual conditions.,"The final analysis shows that the mixed-reality game improved learning by almost five times more than the screen-only alternatives, both in the mouse-controlled and physically controlled conditions. Not only that, but students enjoyed the game more in the mixed-reality conditions. They also determined that simple physical controls like shaking the tablet or pushing the earthquake button did little to improve either learning or enjoyment of the game.","The overall results (including both the prediction and explanation items) indicated that there was a significant effect of media-type (F(1,91)=8.2, p<0.01, d=0.37). The overall improvement from pre to post was 11.3 % in the mixed-reality conditions and 2.4 % in the virtual conditions. Thus, the mixed-reality game improved learning by 4.8 times compared to the screen-only alternatives.","[2.0, 1.0, 2.0]",Computer_Science,test,1.6666666666666667,news,http://www.theepochtimes.com/n3/1354229-why-tablets-cant-replace-real-world-schools/ 10.1145/2702123.2702397,Computer_Science_157,"The final analysis shows that the mixed-reality game improved learning by almost five times more than the screen-only alternatives, both in the mouse-controlled and physically controlled conditions.","Our experimental results provide evidence that observing physical phenomena in the context of an interactive mixedreality game plays an important role for learning and enjoyment, while adding simple physical controls such as having the kids shake the tablet in a screen-only game or press the physical switch in a mixed-reality game does not have an effect on learning or enjoyment.","A game that combined real-world experiments with interactions on a computer tablet improved learning by almost five times more than screen-only alternatives. The final analysis shows that the mixed-reality game improved learning by almost five times more than the screen-only alternatives, both in the mouse-controlled and physically controlled conditions. Not only that, but students enjoyed the game more in the mixed-reality conditions.","This suggests that having a character in the game made it more engaging and memorable for children. Our experimental results provide evidence that observing physical phenomena in the context of an interactive mixedreality game plays an important role for learning and enjoyment, while adding simple physical controls such as having the kids shake the tablet in a screen-only game or press the physical switch in a mixed-reality game does not have an effect on learning or enjoyment. The results revealed that even for this subset there was still a significant effect of mixed reality (over virtual) on learning (p<0.01).","[4.0, 4.0, 3.0, 2.0, 3.0]",Computer_Science,test,3.2,news,http://www.theepochtimes.com/n3/1354229-why-tablets-cant-replace-real-world-schools/ 10.1126/science.aao4408,Computer_Science_159,"The algorithm assigned placements for refugees that they project would increase their chances of finding employment by roughly 40 to 70 percent compared with how the refugees actually fared, according to the new study in Science.","In addition, refugees with certain characteristics, such as language and educational skills, are more likely to succeed economically regardless of the resettlement location to which they are sent (Fig.","In 2016 alone, about 65.6 million people were forced to flee their homes. The algorithm assigned placements for refugees that they project would increase their chances of finding employment by roughly 40 to 70 percent compared with how the refugees actually fared, according to the new study in Science. The group, from Stanford and ETH Zurich, says the algorithm, which could be implemented at virtually no cost, could help resource-constrained governments and resettlement agencies find the best places for refugees to relocate.","It is also one of the most consequential in maximizing refugees' economic integration and self-sufficiency as a first step toward a more comprehensive integration into society (7) (8) (9) . In addition, refugees with certain characteristics, such as language and educational skills, are more likely to succeed economically regardless of the resettlement location to which they are sent (Fig. Finally, the expected employment returns associated with personal characteristics can vary across different resettlement locations (Fig.","[3.0, 3.0, 2.0]",Computer_Science,test,2.6666666666666665,news,http://www.futurity.org/refugee-resettlement-algorithm-1658522-2/ 10.1145/2702123.2702397,Computer_Science_167,"[related] The final analysis shows that the mixed-reality game improved learning by almost five times more than the screen-only alternatives, both in the mouse-controlled and physically controlled conditions.",It is important to isolate the factors that are important for learning in mixed-reality environments.,"[related] The final analysis shows that the mixed-reality game improved learning by almost five times more than the screen-only alternatives, both in the mouse-controlled and physically controlled conditions. Not only that, but students enjoyed the game more in the mixed-reality conditions. They also determined that simple physical controls like shaking the tablet or pushing the earthquake button did little to improve either learning or enjoyment of the game.","Since creating such affordances in the real world is technically challenging, it is tempting to hope that integrating easier-to-develop physical controls into a screen-based environment may improve enjoyment and learning just as well. It is important to isolate the factors that are important for learning in mixed-reality environments. Piaget and Bruner showed that children had an easier time while solving problems when given concrete materials to work .","[2.0, 2.0, 2.0, 2.0]",Computer_Science,test,2.0,news,http://www.futurity.org/tablets-real-world-learning-917682/ 10.1126/science.aao4408,Computer_Science_174,It turned out that refugees with particular backgrounds or skills achieved better outcomes in some locations than others.,"Our approach led to gains of roughly 40 to 70%, on average, in refugees' employment outcomes relative to current assignment practices.","They found that the refugees' eventual economic self-sufficiency depended on a combination of their individual characteristics, such as education level and knowledge of English, and where they were resettled within the country. It turned out that refugees with particular backgrounds or skills achieved better outcomes in some locations than others. In 2016 alone, about 65.6 million people were forced to flee their homes.","Our approach led to gains of roughly 40 to 70%, on average, in refugees' employment outcomes relative to current assignment practices. This approach can provide governments with a practical and cost-efficient policy tool that can be immediately implemented within existing institutional structures. It is also one of the most consequential in maximizing refugees' economic integration and self-sufficiency as a first step toward a more comprehensive integration into society (7-9).","[2.0, 2.0, 2.0]",Computer_Science,test,2.0,news,http://www.futurity.org/refugee-resettlement-algorithm-1658522-2/ 10.1145/2702123.2702397,Computer_Science_18,"They plan to extend their mixed-reality game to different content areas to create a new educational system that bridges the advantages of physical and virtual worlds to improve children's science learning, understanding and enjoyment in a collaborative way.","On the other hand, integrating simple physical controls such as shaking the tablet has little effect.","They also determined that simple physical controls like shaking the tablet or pushing the earthquake button did little to improve either learning or enjoyment of the game. ""Mixed-reality games that support physical observation in the real world have a great potential to enhance learning and enjoyment for young children,"" the researchers say. They plan to extend their mixed-reality game to different content areas to create a new educational system that bridges the advantages of physical and virtual worlds to improve children's science learning, understanding and enjoyment in a collaborative way.","We provided evidence that experiencing physical phenomena accompanied by interactive feedback via depth camera sensing in the real world improves learning (by approximately 5 times compared to a solely screen-based environment), while also enhancing enjoyment significantly. On the other hand, integrating simple physical controls such as shaking the tablet has little effect. Thus, mixed-reality games that support physical observation in the real world have a great potential to enhance learning and enjoyment for young children.","[1.0, 2.0, 3.0, 1.0, 1.0]",Computer_Science,test,1.6,news,http://www.theepochtimes.com/n3/1354229-why-tablets-cant-replace-real-world-schools/ 10.1145/2702123.2702397,Computer_Science_182,A game that combined real-world experiments with interactions on a computer tablet improved learning by almost five times more than screen-only alternatives.,The overall improvement from pre to post was 11.3 % in the mixed-reality conditions and 2.4 % in the virtual conditions.,"A game that combined real-world experiments with interactions on a computer tablet improved learning by almost five times more than screen-only alternatives. The final analysis shows that the mixed-reality game improved learning by almost five times more than the screen-only alternatives, both in the mouse-controlled and physically controlled conditions. Not only that, but students enjoyed the game more in the mixed-reality conditions.","The overall results (including both the prediction and explanation items) indicated that there was a significant effect of media-type (F(1,91)=8.2, p<0.01, d=0.37). The overall improvement from pre to post was 11.3 % in the mixed-reality conditions and 2.4 % in the virtual conditions. Thus, the mixed-reality game improved learning by 4.8 times compared to the screen-only alternatives.","[4.0, 5.0, 2.0, 4.0, 1.0]",Computer_Science,test,4.0,news,http://www.theepochtimes.com/n3/1354229-why-tablets-cant-replace-real-world-schools/ 10.1145/2702123.2702397,Computer_Science_194,"The final analysis shows that the mixed-reality game improved learning by almost five times more than the screen-only alternatives, both in the mouse-controlled and physically controlled conditions.",It is important to isolate the factors that are important for learning in mixed-reality environments.,"A game that combined real-world experiments with interactions on a computer tablet improved learning by almost five times more than screen-only alternatives. The final analysis shows that the mixed-reality game improved learning by almost five times more than the screen-only alternatives, both in the mouse-controlled and physically controlled conditions. Not only that, but students enjoyed the game more in the mixed-reality conditions.","Since creating such affordances in the real world is technically challenging, it is tempting to hope that integrating easier-to-develop physical controls into a screen-based environment may improve enjoyment and learning just as well. It is important to isolate the factors that are important for learning in mixed-reality environments. Piaget and Bruner showed that children had an easier time while solving problems when given concrete materials to work .","[3.0, 3.0, 4.0, 5.0]",Computer_Science,test,3.75,news,http://www.theepochtimes.com/n3/1354229-why-tablets-cant-replace-real-world-schools/ 10.1126/science.aao4408,Computer_Science_199,"After all, having more refugees employed can also ease the financial burden on the Swiss government, cantons, and municipalities.""","In Switzerland, for example, we find that the ability to speak French (i.e., among French-speaking African refugees) results in a larger payoff for refugees assigned to Frenchspeaking cantons than for those assigned to German-speaking cantons ( fig.","He adds that it could also be updated at any time if the composition of refugees and labor market were to change. After all, having more refugees employed can also ease the financial burden on the Swiss government, cantons, and municipalities."" ""The employment gains that we're projecting are quite substantial, and these are gains that could be achieved with almost no additional cost to the governments or resettlement agencies,"" adds Kirk Bansak, a lead author of the study and a political science PhD student at Stanford.","This indicates that there are synergies between places and people; certain characteristics will make a refugee a better match for a particular location. In Switzerland, for example, we find that the ability to speak French (i.e., among French-speaking African refugees) results in a larger payoff for refugees assigned to Frenchspeaking cantons than for those assigned to German-speaking cantons ( fig. A separate model was fit for subgroups of refugees assigned to each location, thus yielding different models for each location and allowing for the discovery of refugee/location synergies.","[1.0, 3.0, 2.0]",Computer_Science,test,2.0,news,http://www.futurity.org/refugee-resettlement-algorithm-1658522-2/ 10.1145/2702123.2702397,Computer_Science_2,"[related] The final analysis shows that the mixed-reality game improved learning by almost five times more than the screen-only alternatives, both in the mouse-controlled and physically controlled conditions.",The overall improvement from pre to post was 11.3 % in the mixed-reality conditions and 2.4 % in the virtual conditions.,"[related] The final analysis shows that the mixed-reality game improved learning by almost five times more than the screen-only alternatives, both in the mouse-controlled and physically controlled conditions. Not only that, but students enjoyed the game more in the mixed-reality conditions. They also determined that simple physical controls like shaking the tablet or pushing the earthquake button did little to improve either learning or enjoyment of the game.","The overall results (including both the prediction and explanation items) indicated that there was a significant effect of media-type (F(1,91)=8.2, p<0.01, d=0.37). The overall improvement from pre to post was 11.3 % in the mixed-reality conditions and 2.4 % in the virtual conditions. Thus, the mixed-reality game improved learning by 4.8 times compared to the screen-only alternatives.","[5.0, 4.0, 5.0, 5.0, 5.0]",Computer_Science,test,4.8,news,http://www.futurity.org/tablets-real-world-learning-917682/ 10.1126/science.aao4408,Computer_Science_20,"The more successful refugees are where they settle, the more welcoming locals are likely to be in the future.","In addition, refugees with certain characteristics, such as language and educational skills, are more likely to succeed economically regardless of the resettlement location to which they are sent (Fig.","Aside from improving individual lives, machine matching also has the potential of helping refugees overall. The more successful refugees are where they settle, the more welcoming locals are likely to be in the future. The researchers' team is in talks with resettlement agencies in both the US and Switzerland to test the algorithm in pilot programs with actual cases.","It is also one of the most consequential in maximizing refugees' economic integration and self-sufficiency as a first step toward a more comprehensive integration into society (7-9). In addition, refugees with certain characteristics, such as language and educational skills, are more likely to succeed economically regardless of the resettlement location to which they are sent (Fig. Finally, the expected employment returns associated with personal characteristics can vary across different resettlement locations (Fig.","[4.0, 4.0, 4.0, 4.0, 4.0]",Computer_Science,test,4.0,news,http://ct.moreover.com/?a=33043872014&p=1pl&v=1&x=ioHTDQjI3HcfKMxGI9-OBQ 10.1126/science.aao4408,Computer_Science_210,"And that could be done at a relatively low cost, a big concern given the surge in the number of global refugees.","In addition, the algorithmic assignment yielded higher employment rates in almost every location, including locations that had higher and lower baseline employment rates.","Unlike other efforts to integrate refugees, such as language lessons or job training, the algorithm could be inserted in the resettlement process pretty seamlessly--it could eventually become a piece of software installed in the computers of the officers' already making the decisions, says Ferwerda. And that could be done at a relatively low cost, a big concern given the surge in the number of global refugees. Aside from improving individual lives, machine matching also has the potential of helping refugees overall.","Our optimized assignment increased the probability of finding employment across the entire distribution of refugees, including those who were least likely and most likely to find work. In addition, the algorithmic assignment yielded higher employment rates in almost every location, including locations that had higher and lower baseline employment rates. On average, the employment rate was 34% under the actual assignment and 48% under the optimized assignment, which means that the optimized assignment would increase the employment rate above the baseline by roughly 41%.","[2.0, 2.0, 1.0, 2.0]",Computer_Science,test,1.75,news,http://ct.moreover.com/?a=33043872014&p=1pl&v=1&x=ioHTDQjI3HcfKMxGI9-OBQ 10.1126/science.aao4408,Computer_Science_211,"""Our approach preserves the ability of policy-makers to set their own parameters and priorities,"" the researchers write.","On average, the employment rate was 34% under the actual assignment and 48% under the optimized assignment, which means that the optimized assignment would increase the employment rate above the baseline by roughly 41%.","A simple change The researchers are not advocating for the algorithm to replace the decision-making of resettlement officials. ""Our approach preserves the ability of policy-makers to set their own parameters and priorities,"" the researchers write. ""For instance, in a computer-assisted assignment process, the algorithm might provide several recommendations, and placement officers could use their own discretion to determine the final assignment or override any suggestions.""","In addition, the algorithmic assignment yielded higher employment rates in almost every location, including locations that had higher and lower baseline employment rates. On average, the employment rate was 34% under the actual assignment and 48% under the optimized assignment, which means that the optimized assignment would increase the employment rate above the baseline by roughly 41%. Our algorithmic assignment considerably increased expected refugee employment over the status quo assignment (Fig.","[3.0, 2.0, 1.0, 1.0, 1.0]",Computer_Science,test,1.6,news,http://www.futurity.org/refugee-resettlement-algorithm-1658522-2/ 10.1145/2702123.2702397,Computer_Science_216,"[related] The final analysis shows that the mixed-reality game improved learning by almost five times more than the screen-only alternatives, both in the mouse-controlled and physically controlled conditions.","We can consider what choice improves learning most over a typical virtual, mouse-control game (#1 in Figure 10 ).","[related] The final analysis shows that the mixed-reality game improved learning by almost five times more than the screen-only alternatives, both in the mouse-controlled and physically controlled conditions. Not only that, but students enjoyed the game more in the mixed-reality conditions. They also determined that simple physical controls like shaking the tablet or pushing the earthquake button did little to improve either learning or enjoyment of the game.","These results show that mixed-reality led to more learning than screen only, for both the mousecontrol and physical-control conditions ( Figure 10 ). We can consider what choice improves learning most over a typical virtual, mouse-control game (#1 in Figure 10 ). The mixed-reality, mouse-control condition (#2) is significantly better (p<0.05), but the virtual, physicalcontrol condition (#3) is not.","[2.0, 3.0, 3.0]",Computer_Science,test,2.6666666666666665,news,http://www.futurity.org/tablets-real-world-learning-917682/ 10.1126/science.aao4408,Computer_Science_218,They predicted the employment rate would have been 73 percent higher among asylum seekers who arrived in 2013 if they had been assigned to the places the algorithm identified as optimal.,Our preferred case-level metric was the predicted probability that at least one refugee in the case would find employment at the location in question.,"The group found that if the algorithm had selected locations for refugees' resettlement, the average employment rate among those refugees would have been roughly 41 percent higher. They predicted the employment rate would have been 73 percent higher among asylum seekers who arrived in 2013 if they had been assigned to the places the algorithm identified as optimal. In Vaud, employment prospects are higher for anyone who speaks French.",Various mapping functions can be used. Our preferred case-level metric was the predicted probability that at least one refugee in the case would find employment at the location in question. Our algorithm is flexible and can accommodate multiple criteria and constraints.,"[2.0, 3.0, 3.0]",Computer_Science,test,2.6666666666666665,news,http://www.futurity.org/refugee-resettlement-algorithm-1658522-2/ 10.1126/science.aao4408,Computer_Science_226,"They found that the refugees' eventual economic self-sufficiency depended on a combination of their individual characteristics, such as education level and knowledge of English, and where they were resettled within the country.","A separate model was fit for subgroups of refugees assigned to each location, thus yielding different models for each location and allowing for the discovery of refugee/location synergies.","They found that the refugees' eventual economic self-sufficiency depended on a combination of their individual characteristics, such as education level and knowledge of English, and where they were resettled within the country. It turned out that refugees with particular backgrounds or skills achieved better outcomes in some locations than others. The algorithm assigned placements for refugees that they project would increase their chances of finding employment by roughly 40 to 70 percent compared with how the refugees actually fared, according to the new study, published in Science.","In Switzerland, for example, we find that the ability to speak French (i.e., among French-speaking African refugees) results in a larger payoff for refugees assigned to Frenchspeaking cantons than for those assigned to German-speaking cantons ( fig. A separate model was fit for subgroups of refugees assigned to each location, thus yielding different models for each location and allowing for the discovery of refugee/location synergies. Various mapping functions can be used.","[4.0, 2.0, 4.0, 2.0, 3.0]",Computer_Science,test,3.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/ycYLqg96qto/ 10.1145/2702123.2702397,Computer_Science_234,"[related] The final analysis shows that the mixed-reality game improved learning by almost five times more than the screen-only alternatives, both in the mouse-controlled and physically controlled conditions.",This result is particularly interesting as it demonstrates better transfer of instruction involving mere physical observing (over flat screen observing) to actual physical interaction with the blocks.,"[related] The final analysis shows that the mixed-reality game improved learning by almost five times more than the screen-only alternatives, both in the mouse-controlled and physically controlled conditions. Not only that, but students enjoyed the game more in the mixed-reality conditions. They also determined that simple physical controls like shaking the tablet or pushing the earthquake button did little to improve either learning or enjoyment of the game.","Thus, the kids in the tangible condition were improving more on building stable towers than those in the virtual condition, for both the mousecontrol and physical-control conditions ( Figure 14 ). This result is particularly interesting as it demonstrates better transfer of instruction involving mere physical observing (over flat screen observing) to actual physical interaction with the blocks. Comparing the scores of the children in different conditions, we saw that the students who were in the mixed-reality condition said they liked the game significantly more than those in the virtual condition (F(1,92)=6.7, p=0.01, d=0.55).","[2.0, 3.0, 2.0]",Computer_Science,test,2.333333333333333,news,http://www.futurity.org/tablets-real-world-learning-917682/ 10.1126/science.aao4408,Computer_Science_240,"The group found that if the algorithm had selected locations for refugees' resettlement, the average employment rate among those refugees would have been roughly 41 percent higher.","A separate model was fit for subgroups of refugees assigned to each location, thus yielding different models for each location and allowing for the discovery of refugee/location synergies.","The group, from Stanford and ETH Zurich, says the algorithm, which could be implemented at virtually no cost, could help resource-constrained governments and resettlement agencies find the best places for refugees to relocate. The group found that if the algorithm had selected locations for refugees' resettlement, the average employment rate among those refugees would have been roughly 41 percent higher. They predicted the employment rate would have been 73 percent higher among asylum seekers who arrived in 2013 if they had been assigned to the places the algorithm identified as optimal.","In Switzerland, for example, we find that the ability to speak French (i.e., among French-speaking African refugees) results in a larger payoff for refugees assigned to Frenchspeaking cantons than for those assigned to German-speaking cantons ( fig. A separate model was fit for subgroups of refugees assigned to each location, thus yielding different models for each location and allowing for the discovery of refugee/location synergies. Various mapping functions can be used.","[2.0, 2.0, 4.0, 3.0, 4.0]",Computer_Science,test,3.0,news,http://www.futurity.org/refugee-resettlement-algorithm-1658522-2/ 10.1073/pnas.1719233115,Computer_Science_242,"""If one has a large number of relationships, it must mean that they are almost all superficial.""","More interestingly, it predicts that when the number of available relationships is small, this structure is inverted, having more close relationships than acquaintances.","""It is impossible to have relationships with 150 people and for them all to be intimate,"" explains co-author Ignacio Tamarit. ""If one has a large number of relationships, it must mean that they are almost all superficial."" The researchers predicted this effect using a mathematical theory and then found that it held true in actual data gathered on the personal networks of isolated immigrant communities in Spain.","Of itself, this distribution yields no structure whatsoever but it is a reasonable More interestingly, it predicts that when the number of available relationships is small, this structure is inverted, having more close relationships than acquaintances. We provide evidence of the existence of both regimes in real communities and analyze the consequences of these findings in our understanding of social groups.","[4.0, 3.0, 4.0, 2.0]",Computer_Science,test,3.25,news,http://ct.moreover.com/?a=34615793773&p=1pl&v=1&x=B9OeehCkV4Axi__oIw0XTg 10.1126/science.aao4408,Computer_Science_247,"""Our approach preserves the ability of policy-makers to set their own parameters and priorities,"" the researchers write.","On average, the thirdyear employment rate was 15% under the actual assignment and 26% under the optimized assignment.","A simple change The researchers are not advocating for the algorithm to replace the decision-making of resettlement officials. ""Our approach preserves the ability of policy-makers to set their own parameters and priorities,"" the researchers write. ""For instance, in a computer-assisted assignment process, the algorithm might provide several recommendations, and placement officers could use their own discretion to determine the final assignment or override any suggestions.""","Similar to the U.S. context, our algorithm increased the predicted probability of finding employment across the entire distribution of refugees. On average, the thirdyear employment rate was 15% under the actual assignment and 26% under the optimized assignment. These results suggest that the data-driven assignment has the potential to increase third-year employment in the Swiss context by about 73%.","[1.0, 1.0, 2.0, 3.0, 1.0]",Computer_Science,test,1.6,news,http://www.futurity.org/refugee-resettlement-algorithm-1658522-2/ 10.1145/2702123.2702397,Computer_Science_258,They also determined that simple physical controls like shaking the tablet or pushing the earthquake button did little to improve either learning or enjoyment of the game.,"showed that children used more meaningful gestures while explaining their predictions when they observed physical blocks in a mixed-reality game, compared to a screen-only version of the same game.","Not only that, but students enjoyed the game more in the mixed-reality conditions. They also determined that simple physical controls like shaking the tablet or pushing the earthquake button did little to improve either learning or enjoyment of the game. ""Mixed-reality games that support physical observation in the real world have a great potential to enhance learning and enjoyment for young children,"" the researchers say.","Experiencing physical phenomena in real life may help people perceive and mentally visualize the physical objects in 3D in their minds, make connections with objects they are familiar with, and as a result remember the concepts better. showed that children used more meaningful gestures while explaining their predictions when they observed physical blocks in a mixed-reality game, compared to a screen-only version of the same game. This result suggests that children may be having more meaningful mental visualizations (demonstrated by the gestures they use) when they interact with 3D objects .","[2.0, 1.0, 1.0, 3.0]",Computer_Science,test,1.75,news,http://www.theepochtimes.com/n3/1354229-why-tablets-cant-replace-real-world-schools/ 10.1145/2702123.2702397,Computer_Science_26,"[related] The final analysis shows that the mixed-reality game improved learning by almost five times more than the screen-only alternatives, both in the mouse-controlled and physically controlled conditions.",This suggests that having a character in the game made it more engaging and memorable for children.,"[related] The final analysis shows that the mixed-reality game improved learning by almost five times more than the screen-only alternatives, both in the mouse-controlled and physically controlled conditions. Not only that, but students enjoyed the game more in the mixed-reality conditions. They also determined that simple physical controls like shaking the tablet or pushing the earthquake button did little to improve either learning or enjoyment of the game.","In addition, children mentioned that they liked the gorilla character in the game, telling their friends about their gorilla friend. This suggests that having a character in the game made it more engaging and memorable for children. Our experimental results provide evidence that observing physical phenomena in the context of an interactive mixedreality game plays an important role for learning and enjoyment, while adding simple physical controls such as having the kids shake the tablet in a screen-only game or press the physical switch in a mixed-reality game does not have an effect on learning or enjoyment.","[3.0, 2.0, 2.0, 2.0]",Computer_Science,test,2.25,news,http://www.futurity.org/tablets-real-world-learning-917682/ 10.1145/2702123.2702397,Computer_Science_263,"[related] The final analysis shows that the mixed-reality game improved learning by almost five times more than the screen-only alternatives, both in the mouse-controlled and physically controlled conditions.","Our 2x2 experiment found no evidence that adding simple forms of hands-on control enhances learning, while demonstrating a large impact of physical observation.","[related] The final analysis shows that the mixed-reality game improved learning by almost five times more than the screen-only alternatives, both in the mouse-controlled and physically controlled conditions. Not only that, but students enjoyed the game more in the mixed-reality conditions. They also determined that simple physical controls like shaking the tablet or pushing the earthquake button did little to improve either learning or enjoyment of the game.","Immersing children in the real world with computer vision-based feedback appears to evoke embodied cognition that enhances learning. Our 2x2 experiment found no evidence that adding simple forms of hands-on control enhances learning, while demonstrating a large impact of physical observation. A general implication for educational game design is that affording physical observation in the real world accompanied by real-time interactive feedback may be more important than affording simple hands-on control on a tablet.","[3.0, 2.0, 1.0, 1.0]",Computer_Science,test,1.75,news,http://www.futurity.org/tablets-real-world-learning-917682/ 10.1073/pnas.1719233115,Computer_Science_267,"For example, people working in small startups might have a larger number of intense relationships than those in the wider corporate world.","More interestingly, it predicts that when the number of available relationships is small, this structure is inverted, having more close relationships than acquaintances.","You could probably extrapolate this effect out to relationships within large or small companies for those of us whose social lives largely overlap with our careers. For example, people working in small startups might have a larger number of intense relationships than those in the wider corporate world. But the bottom line here is that having more close relationships in your life should be possible at any time, but it's going to mean putting in the work, which will probably come at the expense of losing some less intimate relationships.","Of itself, this distribution yields no structure whatsoever but it is a reasonable More interestingly, it predicts that when the number of available relationships is small, this structure is inverted, having more close relationships than acquaintances. We provide evidence of the existence of both regimes in real communities and analyze the consequences of these findings in our understanding of social groups.","[3.0, 5.0, 4.0]",Computer_Science,test,4.0,news,http://ct.moreover.com/?a=34615793773&p=1pl&v=1&x=B9OeehCkV4Axi__oIw0XTg 10.1126/science.aao4408,Computer_Science_269,"The algorithm takes into account a variety of factors that resettlement agencies usually don't, from age to English proficiency to the size of the immigrant community from a refugee's country in any given location.",Our preferred case-level metric was the predicted probability that at least one refugee in the case would find employment at the location in question.,"But what kind of life that will be largely depends on where they end up. The algorithm takes into account a variety of factors that resettlement agencies usually don't, from age to English proficiency to the size of the immigrant community from a refugee's country in any given location. But by weighing in specific details about the refugees and the communities where they are headed, the algorithm can place them where their skills are the most marketable.",Various mapping functions can be used. Our preferred case-level metric was the predicted probability that at least one refugee in the case would find employment at the location in question. Our algorithm is flexible and can accommodate multiple criteria and constraints.,"[3.0, 2.0, 1.0, 1.0]",Computer_Science,test,1.75,news,http://ct.moreover.com/?a=33043872014&p=1pl&v=1&x=ioHTDQjI3HcfKMxGI9-OBQ 10.1145/2702123.2702397,Computer_Science_270,They also determined that simple physical controls like shaking the tablet or pushing the earthquake button did little to improve either learning or enjoyment of the game.,There was no effect of control type and no interaction effects.,"Not only that, but students enjoyed the game more in the mixed-reality conditions. They also determined that simple physical controls like shaking the tablet or pushing the earthquake button did little to improve either learning or enjoyment of the game. ""Mixed-reality games that support physical observation in the real world have a great potential to enhance learning and enjoyment for young children,"" the researchers say.","The average score on the posttests (both the prediction and explanation items) was 45% across the mixed-reality conditions and 39% across the virtual conditions. There was no effect of control type and no interaction effects. These results show that mixed-reality led to more learning than screen only, for both the mousecontrol and physical-control conditions ( Figure 10 ).","[1.0, 3.0, 1.0]",Computer_Science,test,1.6666666666666667,news,http://www.theepochtimes.com/n3/1354229-why-tablets-cant-replace-real-world-schools/ 10.1126/science.aao4408,Computer_Science_28,"They found that the refugees' eventual economic self-sufficiency depended on a combination of their individual characteristics, such as education level and knowledge of English, and where they were resettled within the country.",This indicates that there are synergies between places and people; certain characteristics will make a refugee a better match for a particular location.,"They found that the refugees' eventual economic self-sufficiency depended on a combination of their individual characteristics, such as education level and knowledge of English, and where they were resettled within the country. It turned out that refugees with particular backgrounds or skills achieved better outcomes in some locations than others. The algorithm assigned placements for refugees that they project would increase their chances of finding employment by roughly 40 to 70 percent compared with how the refugees actually fared, according to the new study, published in Science.","Finally, the expected employment returns associated with personal characteristics can vary across different resettlement locations (Fig. This indicates that there are synergies between places and people; certain characteristics will make a refugee a better match for a particular location. In Switzerland, for example, we find that the ability to speak French (i.e., among French-speaking African refugees) results in a larger payoff for refugees assigned to Frenchspeaking cantons than for those assigned to German-speaking cantons ( fig.","[3.0, 2.0, 5.0, 2.0]",Computer_Science,test,3.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/ycYLqg96qto/ 10.1126/science.aao4408,Computer_Science_29,"The algorithm assigned placements for refugees that they project would increase their chances of finding employment by roughly 40 to 70 percent compared with how the refugees actually fared, according to the new study in Science.",This indicates that there are synergies between places and people; certain characteristics will make a refugee a better match for a particular location.,"In 2016 alone, about 65.6 million people were forced to flee their homes. The algorithm assigned placements for refugees that they project would increase their chances of finding employment by roughly 40 to 70 percent compared with how the refugees actually fared, according to the new study in Science. The group, from Stanford and ETH Zurich, says the algorithm, which could be implemented at virtually no cost, could help resource-constrained governments and resettlement agencies find the best places for refugees to relocate.","Finally, the expected employment returns associated with personal characteristics can vary across different resettlement locations (Fig. This indicates that there are synergies between places and people; certain characteristics will make a refugee a better match for a particular location. In Switzerland, for example, we find that the ability to speak French (i.e., among French-speaking African refugees) results in a larger payoff for refugees assigned to Frenchspeaking cantons than for those assigned to German-speaking cantons ( fig.","[4.0, 2.0, 3.0, 2.0]",Computer_Science,test,2.75,news,http://www.futurity.org/refugee-resettlement-algorithm-1658522-2/ 10.1145/2702123.2702397,Computer_Science_291,"""Mixed-reality games that support physical observation in the real world have a great potential to enhance learning and enjoyment for young children,"" the researchers say.","These results show that mixed-reality led to more learning than screen only, for both the mousecontrol and physical-control conditions ( Figure 10 ).","They also determined that simple physical controls like shaking the tablet or pushing the earthquake button did little to improve either learning or enjoyment of the game. ""Mixed-reality games that support physical observation in the real world have a great potential to enhance learning and enjoyment for young children,"" the researchers say. They plan to extend their mixed-reality game to different content areas to create a new educational system that bridges the advantages of physical and virtual worlds to improve children's science learning, understanding and enjoyment in a collaborative way.","There was no effect of control type and no interaction effects. These results show that mixed-reality led to more learning than screen only, for both the mousecontrol and physical-control conditions ( Figure 10 ). We can consider what choice improves learning most over a typical virtual, mouse-control game (#1 in Figure 10 ).","[4.0, 3.0, 4.0, 4.0]",Computer_Science,test,3.75,news,http://www.theepochtimes.com/n3/1354229-why-tablets-cant-replace-real-world-schools/ 10.1145/2702123.2702397,Computer_Science_3,"[related] The final analysis shows that the mixed-reality game improved learning by almost five times more than the screen-only alternatives, both in the mouse-controlled and physically controlled conditions.",There was no effect of control type and no interaction effects.,"[related] The final analysis shows that the mixed-reality game improved learning by almost five times more than the screen-only alternatives, both in the mouse-controlled and physically controlled conditions. Not only that, but students enjoyed the game more in the mixed-reality conditions. They also determined that simple physical controls like shaking the tablet or pushing the earthquake button did little to improve either learning or enjoyment of the game.","The average score on the posttests (both the prediction and explanation items) was 45% across the mixed-reality conditions and 39% across the virtual conditions. There was no effect of control type and no interaction effects. These results show that mixed-reality led to more learning than screen only, for both the mousecontrol and physical-control conditions ( Figure 10 ).","[2.0, 2.0, 3.0, 1.0, 1.0]",Computer_Science,test,1.8,news,http://www.futurity.org/tablets-real-world-learning-917682/ 10.1126/science.aao4408,Computer_Science_300,"""For instance, in a computer-assisted assignment process, the algorithm might provide several recommendations, and placement officers could use their own discretion to determine the final assignment or override any suggestions.""",This approach can provide governments with a practical and cost-efficient policy tool that can be immediately implemented within existing institutional structures.,"""Our approach preserves the ability of policy-makers to set their own parameters and priorities,"" the researchers write. ""For instance, in a computer-assisted assignment process, the algorithm might provide several recommendations, and placement officers could use their own discretion to determine the final assignment or override any suggestions."" Yet in contrast to more expensive policy interventions, such as job or language training for refugees, the results of the algorithm, the code of which is available for free to any organization or government, are promising, the researchers say.","Our approach led to gains of roughly 40 to 70%, on average, in refugees' employment outcomes relative to current assignment practices. This approach can provide governments with a practical and cost-efficient policy tool that can be immediately implemented within existing institutional structures. It is also one of the most consequential in maximizing refugees' economic integration and self-sufficiency as a first step toward a more comprehensive integration into society (7) (8) (9) .","[5.0, 1.0, 3.0, 2.0, 1.0]",Computer_Science,test,2.0,news,http://www.futurity.org/refugee-resettlement-algorithm-1658522-2/ 10.1126/science.aao4408,Computer_Science_307,"The group found that if the algorithm had selected locations for refugees' resettlement, the average employment rate among those refugees would have been roughly 41 percent higher.","Our approach led to gains of roughly 40 to 70%, on average, in refugees' employment outcomes relative to current assignment practices.","The group, from Stanford and ETH Zurich, says the algorithm, which could be implemented at virtually no cost, could help resource-constrained governments and resettlement agencies find the best places for refugees to relocate. The group found that if the algorithm had selected locations for refugees' resettlement, the average employment rate among those refugees would have been roughly 41 percent higher. They predicted the employment rate would have been 73 percent higher among asylum seekers who arrived in 2013 if they had been assigned to the places the algorithm identified as optimal.","For the algorithm to obtain reliable predictions, it is important that the historical assignment process not be determined by unobserved refugee characteristics. Our approach led to gains of roughly 40 to 70%, on average, in refugees' employment outcomes relative to current assignment practices. This approach can provide governments with a practical and cost-efficient policy tool that can be immediately implemented within existing institutional structures.","[4.0, 3.0, 4.0, 3.0]",Computer_Science,test,3.5,news,http://www.futurity.org/refugee-resettlement-algorithm-1658522-2/ 10.1126/science.aao4408,Computer_Science_31,"In the US, chances of finding work rose to 50% with the algorithm, for the median refugee.",Various mapping functions can be used.,"But by weighing in specific details about the refugees and the communities where they are headed, the algorithm can place them where their skills are the most marketable. In the US, chances of finding work rose to 50% with the algorithm, for the median refugee. Location Actual With algorithm 1 0% 75% 2 0% 4% 3 0% 10% 4 0% 15% 5 0% 36% 6 6% 62% 7 6% 59% 8 9% 39% 9 9% 54% 10 17% 20% 11 21% 52% 12 21% 47% 13 24% 43% 14 25% 47% 15 26% 31% 16 26% 41% 17 28% 12% 18 29% 41% 19 29% 42% 20 31% 70% 21 31% 65% 22 32% 46% 23 38% 35% 24 40% 76% 25 40% 42% 26 48% 71% 27 48% 58% 28 48% 69% 29 50% 48% 30 50% 40% 31 50% 86% 32 52% 44% 33 56% 58% 34 62% 69% 35 93% 62% In Switzerland, the algorithm would have increased refugees' employment chances to 26% from 15%.","A separate model was fit for subgroups of refugees assigned to each location, thus yielding different models for each location and allowing for the discovery of refugee/location synergies. Various mapping functions can be used. Our preferred case-level metric was the predicted probability that at least one refugee in the case would find employment at the location in question.","[1.0, 1.0, 1.0, 1.0, 1.0]",Computer_Science,test,1.0,news,http://ct.moreover.com/?a=33043872014&p=1pl&v=1&x=ioHTDQjI3HcfKMxGI9-OBQ 10.1126/science.aao4408,Computer_Science_313,They predicted the employment rate would have been 73 percent higher among asylum seekers who arrived in 2013 if they had been assigned to the places the algorithm identified as optimal.,The results from these tests all show considerable gains.,"The group found that if the algorithm had selected locations for refugees' resettlement, the average employment rate among those refugees would have been roughly 41 percent higher. They predicted the employment rate would have been 73 percent higher among asylum seekers who arrived in 2013 if they had been assigned to the places the algorithm identified as optimal. In Vaud, employment prospects are higher for anyone who speaks French.","These results suggest that the data-driven assignment has the potential to increase third-year employment in the Swiss context by about 73%. The results from these tests all show considerable gains. Our analysis demonstrated large potential improvements, but we did not test the algorithm prospectively.","[3.0, 1.0, 1.0, 2.0, 4.0]",Computer_Science,test,2.2,news,http://www.futurity.org/refugee-resettlement-algorithm-1658522-2/ 10.1126/science.aao4408,Computer_Science_319,"Canton Actual With algorithm OW 0% 40% TI 4% 32% FR 4% 15% LU 7% 18% VS 7% 14% VD 8% 8% BL 11% 12% AG 11% 21% GE 13% 23% ZH 15% 7% BE 16% 35% JU 17% 21% SG 17% 28% SH 20% 51% UR 20% 48% ZG 20% 61% GL 22% 42% BS 25% 25% NE 25% 11% SO 25% 64% GR 29% 64% NW 29% 45% SZ 29% 18% TG 30% 33% AR 33% 46% Here's roughly how the algorithm works: The process starts with a series of models trained to predict where a certain type of refugee is likely to fare best based on previous cases.","In Switzerland, for example, we find that the ability to speak French (i.e., among French-speaking African refugees) results in a larger payoff for refugees assigned to Frenchspeaking cantons than for those assigned to German-speaking cantons ( fig.","Location Actual With algorithm 1 0% 75% 2 0% 4% 3 0% 10% 4 0% 15% 5 0% 36% 6 6% 62% 7 6% 59% 8 9% 39% 9 9% 54% 10 17% 20% 11 21% 52% 12 21% 47% 13 24% 43% 14 25% 47% 15 26% 31% 16 26% 41% 17 28% 12% 18 29% 41% 19 29% 42% 20 31% 70% 21 31% 65% 22 32% 46% 23 38% 35% 24 40% 76% 25 40% 42% 26 48% 71% 27 48% 58% 28 48% 69% 29 50% 48% 30 50% 40% 31 50% 86% 32 52% 44% 33 56% 58% 34 62% 69% 35 93% 62% In Switzerland, the algorithm would have increased refugees' employment chances to 26% from 15%. Canton Actual With algorithm OW 0% 40% TI 4% 32% FR 4% 15% LU 7% 18% VS 7% 14% VD 8% 8% BL 11% 12% AG 11% 21% GE 13% 23% ZH 15% 7% BE 16% 35% JU 17% 21% SG 17% 28% SH 20% 51% UR 20% 48% ZG 20% 61% GL 22% 42% BS 25% 25% NE 25% 11% SO 25% 64% GR 29% 64% NW 29% 45% SZ 29% 18% TG 30% 33% AR 33% 46% Here's roughly how the algorithm works: The process starts with a series of models trained to predict where a certain type of refugee is likely to fare best based on previous cases. In other words, the locations and the number of refugees remain the same, they are just matched more precisely and systematically.","This indicates that there are synergies between places and people; certain characteristics will make a refugee a better match for a particular location. In Switzerland, for example, we find that the ability to speak French (i.e., among French-speaking African refugees) results in a larger payoff for refugees assigned to Frenchspeaking cantons than for those assigned to German-speaking cantons ( fig. A separate model was fit for subgroups of refugees assigned to each location, thus yielding different models for each location and allowing for the discovery of refugee/location synergies.","[2.0, 1.0, 1.0, 1.0]",Computer_Science,test,1.25,news,http://ct.moreover.com/?a=33043872014&p=1pl&v=1&x=ioHTDQjI3HcfKMxGI9-OBQ 10.1145/2702123.2702397,Computer_Science_320,A game that combined real-world experiments with interactions on a computer tablet improved learning by almost five times more than screen-only alternatives.,Another student cited that she thought this was like the next version of smart boards.,"A game that combined real-world experiments with interactions on a computer tablet improved learning by almost five times more than screen-only alternatives. The final analysis shows that the mixed-reality game improved learning by almost five times more than the screen-only alternatives, both in the mouse-controlled and physically controlled conditions. Not only that, but students enjoyed the game more in the mixed-reality conditions.","Another girl said: ""I never thought something we do at school could be so much fun"", while another stated: ""I wish all our science classes were fun like this."" Another student cited that she thought this was like the next version of smart boards. Many kids made comments indicating that the experience of seeing what actually happens in real life was better than having a computer tell them what is going to happen, which suggests that observing physical phenomena in the real world might be more believable, leading to more learning.","[5.0, 2.0, 1.0, 4.0]",Computer_Science,test,2.0,news,http://www.theepochtimes.com/n3/1354229-why-tablets-cant-replace-real-world-schools/ 10.1126/science.aao4408,Computer_Science_349,"They found that the refugees' eventual economic self-sufficiency depended on a combination of their individual characteristics, such as education level and knowledge of English, and where they were resettled within the country.",Our preferred case-level metric was the predicted probability that at least one refugee in the case would find employment at the location in question.,"They found that the refugees' eventual economic self-sufficiency depended on a combination of their individual characteristics, such as education level and knowledge of English, and where they were resettled within the country. It turned out that refugees with particular backgrounds or skills achieved better outcomes in some locations than others. The algorithm assigned placements for refugees that they project would increase their chances of finding employment by roughly 40 to 70 percent compared with how the refugees actually fared, according to the new study, published in Science.",Various mapping functions can be used. Our preferred case-level metric was the predicted probability that at least one refugee in the case would find employment at the location in question. Our algorithm is flexible and can accommodate multiple criteria and constraints.,"[5.0, 1.0, 2.0, 2.0, 2.0]",Computer_Science,test,2.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/ycYLqg96qto/ 10.1126/science.aao4408,Computer_Science_350,"The group, from Stanford and ETH Zurich, says the algorithm, which could be implemented at virtually no cost, could help resource-constrained governments and resettlement agencies find the best places for refugees to relocate.",It is also one of the most consequential in maximizing refugees' economic integration and self-sufficiency as a first step toward a more comprehensive integration into society (7) (8) (9) .,"The algorithm assigned placements for refugees that they project would increase their chances of finding employment by roughly 40 to 70 percent compared with how the refugees actually fared, according to the new study in Science. The group, from Stanford and ETH Zurich, says the algorithm, which could be implemented at virtually no cost, could help resource-constrained governments and resettlement agencies find the best places for refugees to relocate. The group found that if the algorithm had selected locations for refugees' resettlement, the average employment rate among those refugees would have been roughly 41 percent higher.","This approach can provide governments with a practical and cost-efficient policy tool that can be immediately implemented within existing institutional structures. It is also one of the most consequential in maximizing refugees' economic integration and self-sufficiency as a first step toward a more comprehensive integration into society (7) (8) (9) . In addition, refugees with certain characteristics, such as language and educational skills, are more likely to succeed economically regardless of the resettlement location to which they are sent (Fig.","[4.0, 3.0, 3.0, 1.0]",Computer_Science,test,2.75,news,http://www.futurity.org/refugee-resettlement-algorithm-1658522-2/ 10.1145/2702123.2702397,Computer_Science_36,"""Mixed-reality games that support physical observation in the real world have a great potential to enhance learning and enjoyment for young children,"" the researchers say.",showed that children observing physical towers in a mixed-reality game learned physics principles better and showed higher levels of enjoyment compared to students interacting with a solely virtual game on a laptop .,"They also determined that simple physical controls like shaking the tablet or pushing the earthquake button did little to improve either learning or enjoyment of the game. ""Mixed-reality games that support physical observation in the real world have a great potential to enhance learning and enjoyment for young children,"" the researchers say. They plan to extend their mixed-reality game to different content areas to create a new educational system that bridges the advantages of physical and virtual worlds to improve children's science learning, understanding and enjoyment in a collaborative way.","Factoring out the potential contributions to learning of physical observation versus physical control is not only of scientific interest (e.g., when can embodied cognition be evoked --with or without physical activity), but is also of practical importance. showed that children observing physical towers in a mixed-reality game learned physics principles better and showed higher levels of enjoyment compared to students interacting with a solely virtual game on a laptop . This result suggests that observing physical phenomena (along with mixed reality feedback on whether child predictions and physical results match) may enhance learning and enjoyment.","[5.0, 3.0, 2.0, 4.0]",Computer_Science,test,3.5,news,http://www.theepochtimes.com/n3/1354229-why-tablets-cant-replace-real-world-schools/ 10.1126/science.aao4408,Computer_Science_376,"""The employment gains that we're projecting are quite substantial, and these are gains that could be achieved with almost no additional cost to the governments or resettlement agencies,"" said Kirk Bansak, a lead author of the study and a political science PhD student.",Our algorithm is flexible and can accommodate multiple criteria and constraints.,"They predicted the employment rate would have been 73 percent higher among asylum seekers who arrived in 2013 if they had been assigned to the places the algorithm identified as optimal. ""The employment gains that we're projecting are quite substantial, and these are gains that could be achieved with almost no additional cost to the governments or resettlement agencies,"" said Kirk Bansak, a lead author of the study and a political science PhD student. ""By improving an existing process using existing data, our algorithm avoids many of the financial and administrative hurdles that can often impede other policy innovations.""","Our preferred case-level metric was the predicted probability that at least one refugee in the case would find employment at the location in question. Our algorithm is flexible and can accommodate multiple criteria and constraints. For the algorithm to obtain reliable predictions, it is important that the historical assignment process not be determined by unobserved refugee characteristics.","[2.0, 3.0, 2.0, 1.0]",Computer_Science,test,2.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/ycYLqg96qto/ 10.1145/2702123.2702397,Computer_Science_380,"Not only that, but students enjoyed the game more in the mixed-reality conditions.","These results show that mixed-reality led to more learning than screen only, for both the mousecontrol and physical-control conditions ( Figure 10 ).","The final analysis shows that the mixed-reality game improved learning by almost five times more than the screen-only alternatives, both in the mouse-controlled and physically controlled conditions. Not only that, but students enjoyed the game more in the mixed-reality conditions. They also determined that simple physical controls like shaking the tablet or pushing the earthquake button did little to improve either learning or enjoyment of the game.","There was no effect of control type and no interaction effects. These results show that mixed-reality led to more learning than screen only, for both the mousecontrol and physical-control conditions ( Figure 10 ). We can consider what choice improves learning most over a typical virtual, mouse-control game (#1 in Figure 10 ).","[2.0, 1.0, 1.0, 3.0, 3.0]",Computer_Science,test,2.0,news,http://www.theepochtimes.com/n3/1354229-why-tablets-cant-replace-real-world-schools/ 10.1145/2702123.2702397,Computer_Science_387,"They plan to extend their mixed-reality game to different content areas to create a new educational system that bridges the advantages of physical and virtual worlds to improve children's science learning, understanding and enjoyment in a collaborative way.",Another student cited that she thought this was like the next version of smart boards.,"They also determined that simple physical controls like shaking the tablet or pushing the earthquake button did little to improve either learning or enjoyment of the game. ""Mixed-reality games that support physical observation in the real world have a great potential to enhance learning and enjoyment for young children,"" the researchers say. They plan to extend their mixed-reality game to different content areas to create a new educational system that bridges the advantages of physical and virtual worlds to improve children's science learning, understanding and enjoyment in a collaborative way.","Another girl said: ""I never thought something we do at school could be so much fun"", while another stated: ""I wish all our science classes were fun like this."" Another student cited that she thought this was like the next version of smart boards. Many kids made comments indicating that the experience of seeing what actually happens in real life was better than having a computer tell them what is going to happen, which suggests that observing physical phenomena in the real world might be more believable, leading to more learning.","[3.0, 3.0, 2.0, 1.0, 1.0]",Computer_Science,test,2.0,news,http://www.theepochtimes.com/n3/1354229-why-tablets-cant-replace-real-world-schools/ 10.1145/2702123.2702397,Computer_Science_4,"The final analysis shows that the mixed-reality game improved learning by almost five times more than the screen-only alternatives, both in the mouse-controlled and physically controlled conditions.",There was no effect of control type and no interaction effects.,"A game that combined real-world experiments with interactions on a computer tablet improved learning by almost five times more than screen-only alternatives. The final analysis shows that the mixed-reality game improved learning by almost five times more than the screen-only alternatives, both in the mouse-controlled and physically controlled conditions. Not only that, but students enjoyed the game more in the mixed-reality conditions.","The average score on the posttests (both the prediction and explanation items) was 45% across the mixed-reality conditions and 39% across the virtual conditions. There was no effect of control type and no interaction effects. These results show that mixed-reality led to more learning than screen only, for both the mousecontrol and physical-control conditions ( Figure 10 ).","[2.0, 1.0, 1.0, 1.0, 1.0]",Computer_Science,test,1.2,news,http://www.theepochtimes.com/n3/1354229-why-tablets-cant-replace-real-world-schools/ 10.1038/s41746-018-0045-1,Computer_Science_412,"Compared with routine inspections performed by the health department, it had a higher precision rate of identifying unsafe restaurants.",We used this information to focus restaurant inspections in two cities and demonstrated that FINDER improves the accuracy of health inspections; restaurants identified by FINDER are 3.1 times as likely to be deemed unsafe during the inspection as restaurants identified by existing methods.,"The researchers noted that Chicago has one of the most advanced monitoring programs in the nation and already employs social media mining techniques, yet this new model proved more precise in identifying restaurants that had food safety violations. Compared with routine inspections performed by the health department, it had a higher precision rate of identifying unsafe restaurants. When the researchers compared the model with routine inspections by health departments in Las Vegas and Chicago, they found that the overall rate across both cities of unsafe restaurants detected by the model was 52.3%, whereas the overall rate of detection of unsafe restaurants via routine inspections across the two cities was 22.7%.","We used this information to focus restaurant inspections in two cities and demonstrated that FINDER improves the accuracy of health inspections; restaurants identified by FINDER are 3.1 times as likely to be deemed unsafe during the inspection as restaurants identified by existing methods. Additionally, FINDER enables us to ascertain previously intractable epidemiological information, for example, in 38% of cases the restaurant potentially causing food poisoning was not the last one visited, which may explain the lower precision of complaint-based inspections. We found that FINDER is able to reliably identify restaurants that have an active lapse in food safety, allowing for implementation of corrective actions that would prevent the potential spread of foodborne illness.","[4.0, 5.0, 5.0, 2.0]",Computer_Science,test,5.0,news,http://ct.moreover.com/?a=37608429734&p=1pl&v=1&x=DQHTVVIaGMnCSIl1jSYnFw 10.1140/epjds/s13688-017-0110-z,Computer_Science_418,"""This is preliminary work, and it needs to be more thoroughly tested, vetted and replicated before we can safely claim that an algorithm can truly identify markers of depression in Instagram posts,"" Reece said.","Our results supported Hypothesis , that markers of depression are observable in Instagram user behavior, and Hypothesis , that these depressive signals are detectable in posts made even before the date of first diagnosis.","However, Reece warned that the program still needs a lot more fine tuning. ""This is preliminary work, and it needs to be more thoroughly tested, vetted and replicated before we can safely claim that an algorithm can truly identify markers of depression in Instagram posts,"" Reece said. The real promise held by this line of research could be in suicide prevention, Galynker said.","The modest positive correlation of human-rated happiness with the presence and number of faces in a photograph was the only exception to this trend. Our results supported Hypothesis , that markers of depression are observable in Instagram user behavior, and Hypothesis , that these depressive signals are detectable in posts made even before the date of first diagnosis. Human ratings proved capable of distinguishing between Instagram posts made by depressed and healthy individuals (Hypothesis a), but showed little or no correlation with most computational features (Hypothesis b).","[5.0, 4.0, 4.0, 3.0, 2.0]",Computer_Science,test,3.6,news,http://healthmedicinet.com/news/instagram-photos-may-offer-snapshot-of-mental-health/ 10.1145/2702123.2702397,Computer_Science_43,"""Mixed-reality games that support physical observation in the real world have a great potential to enhance learning and enjoyment for young children,"" the researchers say.",This result suggests that observing physical phenomena (along with mixed reality feedback on whether child predictions and physical results match) may enhance learning and enjoyment.,"They also determined that simple physical controls like shaking the tablet or pushing the earthquake button did little to improve either learning or enjoyment of the game. ""Mixed-reality games that support physical observation in the real world have a great potential to enhance learning and enjoyment for young children,"" the researchers say. They plan to extend their mixed-reality game to different content areas to create a new educational system that bridges the advantages of physical and virtual worlds to improve children's science learning, understanding and enjoyment in a collaborative way.","showed that children observing physical towers in a mixed-reality game learned physics principles better and showed higher levels of enjoyment compared to students interacting with a solely virtual game on a laptop . This result suggests that observing physical phenomena (along with mixed reality feedback on whether child predictions and physical results match) may enhance learning and enjoyment. After all, it is intuitive to attribute potential benefits of tangible computing to physical interaction rather than physical observation.","[5.0, 4.0, 2.0, 5.0, 3.0]",Computer_Science,test,3.8,news,http://www.theepochtimes.com/n3/1354229-why-tablets-cant-replace-real-world-schools/ 10.1145/3290605.3300790,Computer_Science_430,The model predicts the players' task success rate when latency is added to the gaming environment.,The new model built on these assumptions accurately predicts the effect of end-to-end latency on user error rate for the task.,"This cognitive model is capable of predicting the success rate of a user when there is latency in a 'moving target selection' task which requires button input in a time constrained situation. The model predicts the players' task success rate when latency is added to the gaming environment. In fact, this research succeeded in modifying the pillar heights of the Flappy Bird game, allowing the players to maintain their gaming performance regardless of the added latency.","For a moving-target selection task with zero latency, a model for predicting the user's error rate already exists . The new model built on these assumptions accurately predicts the effect of end-to-end latency on user error rate for the task. When geometric compensation is applied, the model can predict the corresponding error rate, thereby facilitating control of game difficulty level when latency exists.","[3.0, 3.0, 5.0, 5.0]",Computer_Science,test,4.0,news,http://ct.moreover.com/?a=39534036089&p=1pl&v=1&x=94vcJSTaVeuHBl3fGvnKHg 10.1287/orsc.2014.0900,Computer_Science_441,"Additional surveys revealed that people who claimed to have experienced ostracism were significantly more likely to report a degraded sense of workplace belonging and commitment, a stronger intention to quit their job, and a larger proportion of health problems.","We believe a sense of belonging will at least partially mediate the relationship between ostracism and employee outcomes because ostracism threatens other psychosocial needs, even if the need to belong is the most fundamental and directly affected of these (cf.","First they determined that people consistently rate workplace ostracism as less socially inappropriate, less psychologically harmful and less likely to be prohibited than workplace harassment. Additional surveys revealed that people who claimed to have experienced ostracism were significantly more likely to report a degraded sense of workplace belonging and commitment, a stronger intention to quit their job, and a larger proportion of health problems. ""There is a tremendous effort underway to counter bullying in workplaces and schools, which is definitely important.","Employees' sense of belonging at least partially mediates the relationships between ostracism and their (a) personal well-being, (b) work-related attitudes, and (c) turnover. We believe a sense of belonging will at least partially mediate the relationship between ostracism and employee outcomes because ostracism threatens other psychosocial needs, even if the need to belong is the most fundamental and directly affected of these (cf. A total of 146 participants opened the link to the survey, of which 100 were completed (44% male; mean age in years = 32.64, S.D.","[4.0, 4.0, 2.0, 3.0, 3.0]",Computer_Science,test,3.2,news,http://www.sciencedaily.com/releases/2014/05/140529100715.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29 10.1038/s41467-018-06930-7,Computer_Science_449,"The analysis also revealed that bots amplify a message's volume and visibility until it's more likely to be shared broadly, despite only representing a small fraction of the accounts that spread viral messages.",Relatively few accounts are responsible for a large share of the traffic that carries misinformation.,"The brief length of this time -- two to 10 seconds -- highlights the challenges of countering the spread of misinformation online. ""This study finds that bots significantly contribute to the spread of misinformation online -- as well as shows how quickly these messages can spread,"" said Filippo Menczer, a professor in the IU School of Informatics, Computing and Engineering, who led the study. The analysis also revealed that bots amplify a message's volume and visibility until it's more likely to be shared broadly, despite only representing a small fraction of the accounts that spread viral messages.","Our analysis provides quantitative empirical evidence of the key role played by social bots in the viral spread of fake news online. Relatively few accounts are responsible for a large share of the traffic that carries misinformation. These accounts are likely bots, and we uncovered several manipulation strategies they use.","[3.0, 4.0, 4.0, 4.0, 4.0]",Computer_Science,test,3.8,news,http://ct.moreover.com/?a=37758732647&p=1pl&v=1&x=xhXZa1BARkQuUbzD5r3XtQ 10.1126/science.aao4408,Computer_Science_45,"The group found that if the algorithm had selected locations for refugees' resettlement, the average employment rate among those refugees would have been roughly 41 percent higher.",Various mapping functions can be used.,"The group, from Stanford and ETH Zurich, says the algorithm, which could be implemented at virtually no cost, could help resource-constrained governments and resettlement agencies find the best places for refugees to relocate. The group found that if the algorithm had selected locations for refugees' resettlement, the average employment rate among those refugees would have been roughly 41 percent higher. They predicted the employment rate would have been 73 percent higher among asylum seekers who arrived in 2013 if they had been assigned to the places the algorithm identified as optimal.","A separate model was fit for subgroups of refugees assigned to each location, thus yielding different models for each location and allowing for the discovery of refugee/location synergies. Various mapping functions can be used. Our preferred case-level metric was the predicted probability that at least one refugee in the case would find employment at the location in question.","[2.0, 1.0, 3.0]",Computer_Science,test,2.0,news,http://www.futurity.org/refugee-resettlement-algorithm-1658522-2/ 10.1073/pnas.1717729115,Computer_Science_456,"They found that assembly members on the political left used novel ways of speaking, some of which caught on and gained influence, while more conservative members used familiar word combinations to delay change.",Our analysis reveals clear differences between how the left-and right-wing figures created and transmitted patterns of language use.,"By analyzing word patterns from the French Revolution Digital Archive to determine how novel they were and whether they persisted or disappeared, the researchers provided evidence for the argument that debates in the assembly produced the revolution's ideals and principles. They found that assembly members on the political left used novel ways of speaking, some of which caught on and gained influence, while more conservative members used familiar word combinations to delay change. Members who were charismatic and made their case in new ways were more effective in getting their proposals accepted.","This provides a new window into qualitative analyses, which usually focus on analyzing the logic of particular ideas and arguments over time . Our analysis reveals clear differences between how the left-and right-wing figures created and transmitted patterns of language use. Conservatives may indeed ""stand athwart history, yelling Stop"" ; our results show that here they did so less by redirecting conversation from one set of patterns to another than by maintaining the alreadyestablished patterns of the conversations in which they participated.","[5.0, 4.0, 4.0, 5.0, 5.0]",Computer_Science,test,4.6,news,http://ct.moreover.com/?a=33824214512&p=1pl&v=1&x=NeMlYOii7Rvv8K9BlEPk-A 10.1126/science.aao4408,Computer_Science_46,"But by weighing in specific details about the refugees and the communities where they are headed, the algorithm can place them where their skills are the most marketable.",The results from these tests all show considerable gains.,"The algorithm takes into account a variety of factors that resettlement agencies usually don't, from age to English proficiency to the size of the immigrant community from a refugee's country in any given location. But by weighing in specific details about the refugees and the communities where they are headed, the algorithm can place them where their skills are the most marketable. In the US, chances of finding work rose to 50% with the algorithm, for the median refugee.","These results suggest that the data-driven assignment has the potential to increase third-year employment in the Swiss context by about 73%. The results from these tests all show considerable gains. Our analysis demonstrated large potential improvements, but we did not test the algorithm prospectively.","[1.0, 1.0, 1.0, 2.0, 1.0]",Computer_Science,test,1.2,news,http://ct.moreover.com/?a=33043872014&p=1pl&v=1&x=ioHTDQjI3HcfKMxGI9-OBQ 10.1126/scirobotics.aau3038,Computer_Science_485,It is also able to perform 180-degree turns on horizontal surfaces.,"In addition, we verified that the robot still retained horizontal locomotion capabilities comparable with HAMR-VI.","It walked at speeds comparable to other small climbing robots on inverted surfaces and slightly slower than other climbing robots on vertical surfaces, but was significantly faster than other robots on horizontal surfaces, making it a good candidate for exploring environments that have a variety of surfaces in different arrangements in space. It is also able to perform 180-degree turns on horizontal surfaces. HAMR-E also successfully maneuvered around a curved, inverted section of a jet engine while staying attached, and its passive ankle joints and adhesive foot pads were able to accommodate the rough and uneven features of the engine surface simply by increasing the electroadhesion voltage.","Gravitational forces acting against the direction of motion reduced the effective stride length during vertical locomotion to about 75% of forward displacement achieved during inverted locomotion ( fig. In addition, we verified that the robot still retained horizontal locomotion capabilities comparable with HAMR-VI. Specifically, it achieved forward velocities of 7.5 to 140.4 mm s −1 with the trot gait over stride frequencies ranging from 2 to 65 Hz.","[2.0, 4.0, 1.0, 1.0]",Computer_Science,test,1.0,news,http://ct.moreover.com/?a=38033830057&p=1pl&v=1&x=4ODK2QNV_6TMrwSAULqg3g 10.7717/peerj-cs.38,Computer_Science_489,"The other datasets, which contained identifiers, enabled the scientists to confirm that information access behavior at the community level reflected the behavior of individual users.","While we wish to ultimately understand the biases experienced by individuals, the diversity measurements based on anonymous traffic data do not distinguish between users, and therefore they reveal a collective social bubble, as illustrated in Fig.","""These results suggest the conflation of these previously distinct activities may be contributing to a growing 'bubble effect' in information consumption."" The other datasets, which contained identifiers, enabled the scientists to confirm that information access behavior at the community level reflected the behavior of individual users. ""Compared to a baseline of information-seeking activities, this evidence shows, empirically, that social media does in fact expose communities and individuals to a significantly narrower range of news sources, despite the many information channels on the medium,"" Nikolov said.","4 illustrates the top targets of traffic from search and social media on a typical week. While we wish to ultimately understand the biases experienced by individuals, the diversity measurements based on anonymous traffic data do not distinguish between users, and therefore they reveal a collective social bubble, as illustrated in Fig. It is at first sight unclear whether the collective bubble implies individual bubbles, or tells us anything at all about individual exposure.","[4.0, 2.0, 4.0, 3.0, 1.0]",Computer_Science,test,2.8,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/-DwO-braayI/ 10.1126/science.aao4408,Computer_Science_50,"In the US, chances of finding work rose to 50% with the algorithm, for the median refugee.","Finally, the expected employment returns associated with personal characteristics can vary across different resettlement locations (Fig.","But by weighing in specific details about the refugees and the communities where they are headed, the algorithm can place them where their skills are the most marketable. In the US, chances of finding work rose to 50% with the algorithm, for the median refugee. Location Actual With algorithm 1 0% 75% 2 0% 4% 3 0% 10% 4 0% 15% 5 0% 36% 6 6% 62% 7 6% 59% 8 9% 39% 9 9% 54% 10 17% 20% 11 21% 52% 12 21% 47% 13 24% 43% 14 25% 47% 15 26% 31% 16 26% 41% 17 28% 12% 18 29% 41% 19 29% 42% 20 31% 70% 21 31% 65% 22 32% 46% 23 38% 35% 24 40% 76% 25 40% 42% 26 48% 71% 27 48% 58% 28 48% 69% 29 50% 48% 30 50% 40% 31 50% 86% 32 52% 44% 33 56% 58% 34 62% 69% 35 93% 62% In Switzerland, the algorithm would have increased refugees' employment chances to 26% from 15%.","In addition, refugees with certain characteristics, such as language and educational skills, are more likely to succeed economically regardless of the resettlement location to which they are sent (Fig. Finally, the expected employment returns associated with personal characteristics can vary across different resettlement locations (Fig. This indicates that there are synergies between places and people; certain characteristics will make a refugee a better match for a particular location.","[3.0, 1.0, 2.0]",Computer_Science,test,2.0,news,http://ct.moreover.com/?a=33043872014&p=1pl&v=1&x=ioHTDQjI3HcfKMxGI9-OBQ 10.1016/j.neuroimage.2013.05.090,Computer_Science_500,"However, they say that this is the first imaging study to search for differences associated with breastfeeding in the brains of very young, healthy children.","While the exact mechanism(s) that underlie these observed VF M differences remain unclear, our results lend support to the hypothesis that the docosahexaenoic and arachidonic acids present in breast milk promote preferential neural growth and white matter development.","The results of their study are detailed online in the journal NeuroImage. However, they say that this is the first imaging study to search for differences associated with breastfeeding in the brains of very young, healthy children. ""We show that they're there almost right off the bat.""","We have also shown extended breastfeeding is positively associated with increased VF M in somatosensory, auditory and language areas and, in turn, with increased language performance, visual reception and motor control performance. While the exact mechanism(s) that underlie these observed VF M differences remain unclear, our results lend support to the hypothesis that the docosahexaenoic and arachidonic acids present in breast milk promote preferential neural growth and white matter development. For example, the high cholesterol content of breast milk may provide a ready supply from which oligodendrocytes can develop myelin membranes.","[2.0, 3.0, 3.0, 4.0]",Computer_Science,test,3.0,news,http://www.redorbit.com/news/health/1112868118/breastfeeding-boosts-baby-brain-060713/ 10.1126/science.aao4408,Computer_Science_51,"Location Actual With algorithm 1 0% 75% 2 0% 4% 3 0% 10% 4 0% 15% 5 0% 36% 6 6% 62% 7 6% 59% 8 9% 39% 9 9% 54% 10 17% 20% 11 21% 52% 12 21% 47% 13 24% 43% 14 25% 47% 15 26% 31% 16 26% 41% 17 28% 12% 18 29% 41% 19 29% 42% 20 31% 70% 21 31% 65% 22 32% 46% 23 38% 35% 24 40% 76% 25 40% 42% 26 48% 71% 27 48% 58% 28 48% 69% 29 50% 48% 30 50% 40% 31 50% 86% 32 52% 44% 33 56% 58% 34 62% 69% 35 93% 62% In Switzerland, the algorithm would have increased refugees' employment chances to 26% from 15%.",Various mapping functions can be used.,"In the US, chances of finding work rose to 50% with the algorithm, for the median refugee. Location Actual With algorithm 1 0% 75% 2 0% 4% 3 0% 10% 4 0% 15% 5 0% 36% 6 6% 62% 7 6% 59% 8 9% 39% 9 9% 54% 10 17% 20% 11 21% 52% 12 21% 47% 13 24% 43% 14 25% 47% 15 26% 31% 16 26% 41% 17 28% 12% 18 29% 41% 19 29% 42% 20 31% 70% 21 31% 65% 22 32% 46% 23 38% 35% 24 40% 76% 25 40% 42% 26 48% 71% 27 48% 58% 28 48% 69% 29 50% 48% 30 50% 40% 31 50% 86% 32 52% 44% 33 56% 58% 34 62% 69% 35 93% 62% In Switzerland, the algorithm would have increased refugees' employment chances to 26% from 15%. Canton Actual With algorithm OW 0% 40% TI 4% 32% FR 4% 15% LU 7% 18% VS 7% 14% VD 8% 8% BL 11% 12% AG 11% 21% GE 13% 23% ZH 15% 7% BE 16% 35% JU 17% 21% SG 17% 28% SH 20% 51% UR 20% 48% ZG 20% 61% GL 22% 42% BS 25% 25% NE 25% 11% SO 25% 64% GR 29% 64% NW 29% 45% SZ 29% 18% TG 30% 33% AR 33% 46% Here's roughly how the algorithm works: The process starts with a series of models trained to predict where a certain type of refugee is likely to fare best based on previous cases.","A separate model was fit for subgroups of refugees assigned to each location, thus yielding different models for each location and allowing for the discovery of refugee/location synergies. Various mapping functions can be used. Our preferred case-level metric was the predicted probability that at least one refugee in the case would find employment at the location in question.","[1.0, 1.0, 1.0]",Computer_Science,test,1.0,news,http://ct.moreover.com/?a=33043872014&p=1pl&v=1&x=ioHTDQjI3HcfKMxGI9-OBQ 10.1016/j.specom.2015.11.001,Computer_Science_510,"If we read the same paragraph, he would need to fix about 8% of the transcription and I'd need to fix 21%.","Otherwise, the percent errors are less than 10 percent and the absolute errors are largely constrained to be less than f o /4.","He might get 92% accuracy and I would get 79% accuracy. If we read the same paragraph, he would need to fix about 8% of the transcription and I'd need to fix 21%. My mixed-race female friend, Jada, is likely to get 10% lower accuracy than me.","These errors occur for the same reasons discussed in regard to the simulations in Fig. Otherwise, the percent errors are less than 10 percent and the absolute errors are largely constrained to be less than f o /4. The spectrographic display based on the LP algorithm (bottom row) also provides a fairly clear visual representation of the formants in the first simulation (left panel), except around 0.7 s where the f o is rapidly decreasing.","[1.0, 1.0, 4.0, 1.0, 1.0]",Computer_Science,test,1.0,news,http://ct.moreover.com/?a=39193964299&p=1pl&v=1&x=vsMkHWnrhl_lIRRPl8ZFbg 10.1007/s00799-012-0092-1,Computer_Science_513,"Considering your own data So yes, the internet is rotting, but archivists and digital librarians like myself knew it was rotten already, as did anyone who ever got a ""404 File Not Found"" error.",Relevance of the developed cost model to the reality of the archiving practices in the organisation ensures understanding of the model by employees and managers.,"Budgeting models suggest a 10-year preservation expense of around $2.50 per gigabyte, or $2,500 per terabyte, or $625,000 for the files MySpace failed to preserve. Considering your own data So yes, the internet is rotting, but archivists and digital librarians like myself knew it was rotten already, as did anyone who ever got a ""404 File Not Found"" error. Where there is economic incentive to keep and use data--such as user information, profiles, or browsing history--it may exist for quite a long time.","Of major importance are also characteristics like relevance, accuracy and usability. Relevance of the developed cost model to the reality of the archiving practices in the organisation ensures understanding of the model by employees and managers. They all have added much to our understanding of the factors affecting a cost model in this field .","[1.0, 1.0, 1.0, 1.0]",Computer_Science,test,1.0,news,http://ct.moreover.com/?a=39269137564&p=1pl&v=1&x=lH46e_XHXsFu51T44Iy_VA 10.1007/s13278-018-0503-4,Computer_Science_521,"Also Read: ZTE Woes May Boost Network Rivals Ericsson And Nokia It constructs a link prediction classifier that can estimate, with high accuracy, the probability of a link existing between two users.",3.2.,"Also Read: Netflix to Soon Have Its Own Movie Theater Chain: Report ""Overall, the results demonstrated that in a real-life friendship scenario we can detect people who have the strongest friendship ties as well as malicious users, even on Twitter,"" the researchers said. Also Read: ZTE Woes May Boost Network Rivals Ericsson And Nokia It constructs a link prediction classifier that can estimate, with high accuracy, the probability of a link existing between two users. ""We tested our algorithm on simulated and real-world data sets on 10 different social networks and it performed well on both,"" Kagan said.","Vertices that have a small number of neighbors are less relevant, since there is not enough information to determine their behavior ). 3.2. Delitsch found that there were 12 outliers out of 53 students, which Heidler et al.","[1.0, 1.0, 1.0, 1.0]",Computer_Science,test,1.0,news,http://ct.moreover.com/?a=33843844856&p=1pl&v=1&x=Uf3QxlXcvVq85hmt3_EYnA 10.1038/nature15693,Computer_Science_528,The Purkinje cells appear to be organized based on a preference for error in only a small part of the task space.,"We found that if we organized the simple spikes of the Purkinje cells based on each cell's complex-spike properties, additional features of the population activity were unmasked.","For example, Shadmehr found that when the monkeys missed the target by 3 degrees of distance, a complex spike appeared after 100 milliseconds, and if the monkeys missed by 8 degrees, a complex spike appeared in 120 milliseconds. The Purkinje cells appear to be organized based on a preference for error in only a small part of the task space. When you experience an error to the right, it causes learning by engaging Purkinje cells that register that error.","The input from the olive produces complex spikes in the Purkinje cells. We found that if we organized the simple spikes of the Purkinje cells based on each cell's complex-spike properties, additional features of the population activity were unmasked. Figure 3b shows the change in population response from the baseline level when a saccade was made in the same direction as CS-off.","[3.0, 3.0, 3.0, 3.0]",Computer_Science,test,3.0,news,http://ct.moreover.com/?a=33963927340&p=1pl&v=1&x=CrMfYdpoMsy2moacs_aNBQ 10.1145/3178876.3186141,Computer_Science_529,It's possible these communities just naturally foster heated debate among different subreddits.,"While these interactions are initiated by the highly active users of the source community, the attackers and defenders who actually get mobilized to participate in the negative mobilization are much less active than them-a finding that dovetails with psychological studies showing that peripheral group members are more likely to This is calculated using comments made in past 30 days.","Others, like r/nintendoswitch and r/hearthstone, are surprising to see on this list. It's possible these communities just naturally foster heated debate among different subreddits. The study's authors didn't speculate about why these communities were so controversial.","Overall, we find that negative mobilizations are initiated by a handful of communities that attack highly similar communities. While these interactions are initiated by the highly active users of the source community, the attackers and defenders who actually get mobilized to participate in the negative mobilization are much less active than them-a finding that dovetails with psychological studies showing that peripheral group members are more likely to This is calculated using comments made in past 30 days. ), and interestingly we see this effect even on Reddit, which is pseudonymous.","[2.0, 3.0, 3.0, 3.0, 1.0]",Computer_Science,test,2.4,news,http://ct.moreover.com/?a=33574570615&p=1pl&v=1&x=3VxA8QsfOdrEeuflPumJLg 10.1038/s41586-018-0200-5,Computer_Science_530,Picking up the pace on quantum technology is important if we're to overcome the numerous obstacles in the way of making quantum computing a practicality.,The states output from such a black-box will have a fidelity with a Bell state of,"Which is why this latest experiment is so exciting. This rapid fire, trial-and-error method is combined with ways to ensure the quantum state is protected from outside interference, meaning for the first time entanglement can be created faster than it's lost. Picking up the pace on quantum technology is important if we're to overcome the numerous obstacles in the way of making quantum computing a practicality.","This protocol allows entangled states to be delivered at specified times, but with a finite probability of success. The states output from such a black-box will have a fidelity with a Bell state of The maximum achievable fidelity F max det of this deterministic state delivery protocol, found by optimising p succ , is also only determined by the quantum link efficiency η link .","[4.0, 1.0, 1.0, 1.0, 1.0]",Computer_Science,test,1.0,news,http://ct.moreover.com/?a=34316423366&p=1pl&v=1&x=Zges5312Qgs8-RxzKPGbXw 10.1073/pnas.1405698111,Computer_Science_535,"It was very puzzling.""","These results, consistently found by sampling over 20 cells, confirm the prediction from simulations: while all the bacteria point in the same direction (outward), the bulk microswimmers move overall in a backward fashion, opposite to the boundary layer motion.","But there was no intuitive way to explain what was happening with the dual-motion vortex. It was very puzzling."" Those simulations showed that when individuals swimming in random trajectories start bumping into each other in a confined circular space, they tend to orient each other to the same angle relative to the circular boundary.","Yet, the relation between the flagella position and the mean membrane position and the flagella bundling at the rear of the bacteria reveal that the cell is pointing to the topleft corner, in a direction opposite to its motion. These results, consistently found by sampling over 20 cells, confirm the prediction from simulations: while all the bacteria point in the same direction (outward), the bulk microswimmers move overall in a backward fashion, opposite to the boundary layer motion. As shown in previous sections, experiments and simulations with both steric and hydrodynamical interactions are in qualitative agreement on both micro-and macroscopic scales.","[1.0, 1.0, 1.0, 1.0, 1.0]",Computer_Science,test,1.0,news,http://www.sciencedaily.com/releases/2014/06/140623154757.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29 10.1145/2702123.2702397,Computer_Science_54,"""Mixed-reality games that support physical observation in the real world have a great potential to enhance learning and enjoyment for young children,"" the researchers say.",This suggests that having a character in the game made it more engaging and memorable for children.,"They also determined that simple physical controls like shaking the tablet or pushing the earthquake button did little to improve either learning or enjoyment of the game. ""Mixed-reality games that support physical observation in the real world have a great potential to enhance learning and enjoyment for young children,"" the researchers say. They plan to extend their mixed-reality game to different content areas to create a new educational system that bridges the advantages of physical and virtual worlds to improve children's science learning, understanding and enjoyment in a collaborative way.","In addition, children mentioned that they liked the gorilla character in the game, telling their friends about their gorilla friend. This suggests that having a character in the game made it more engaging and memorable for children. Our experimental results provide evidence that observing physical phenomena in the context of an interactive mixedreality game plays an important role for learning and enjoyment, while adding simple physical controls such as having the kids shake the tablet in a screen-only game or press the physical switch in a mixed-reality game does not have an effect on learning or enjoyment.","[2.0, 3.0, 2.0, 2.0]",Computer_Science,test,2.25,news,http://www.theepochtimes.com/n3/1354229-why-tablets-cant-replace-real-world-schools/ 10.1126/science.aal2014,Computer_Science_542,The best solution didn't appear in any single model.,"1, D and E).","It took a crowd to solve this problem. The best solution didn't appear in any single model. ""A DREAM Challenge is more like hitting a pinata at a party than a normal research project: Everyone swings, and even if your algorithms don't break it open, you still contribute to the solution,"" Meyer says.","I n vision and hearing, the wavelength of light and frequency of sound are highly predictive of color and tone. 1, D and E). This yielded a number of strong positive interactions, including those between ""garlic"" and ""fish""; ""musky"" and ""sweaty""; and ""sweet"" and ""bakery""; and among ""fruit,"" ""acid,"" and ""urinous""; and a negative interaction between pleasantness and ""decayed"" (Fig.","[1.0, 1.0, 1.0, 1.0]",Computer_Science,test,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/mtsEPluNN2E/ 10.1145/2702123.2702397,Computer_Science_55,"[related] The final analysis shows that the mixed-reality game improved learning by almost five times more than the screen-only alternatives, both in the mouse-controlled and physically controlled conditions.","On the other hand, integrating simple physical controls such as shaking the tablet has little effect.","[related] The final analysis shows that the mixed-reality game improved learning by almost five times more than the screen-only alternatives, both in the mouse-controlled and physically controlled conditions. Not only that, but students enjoyed the game more in the mixed-reality conditions. They also determined that simple physical controls like shaking the tablet or pushing the earthquake button did little to improve either learning or enjoyment of the game.","We provided evidence that experiencing physical phenomena accompanied by interactive feedback via depth camera sensing in the real world improves learning (by approximately 5 times compared to a solely screen-based environment), while also enhancing enjoyment significantly. On the other hand, integrating simple physical controls such as shaking the tablet has little effect. Thus, mixed-reality games that support physical observation in the real world have a great potential to enhance learning and enjoyment for young children.","[3.0, 1.0, 3.0, 1.0, 2.0]",Computer_Science,test,2.0,news,http://www.futurity.org/tablets-real-world-learning-917682/ 10.1126/scirobotics.aau0307,Computer_Science_555,"These scattered lights are symmetric when compared to the location of the sun, which is why ants can use them to get their orientation while navigating.",AntBot's navigation performances involved a very small number of pixels in comparison with traditional engineering solutions (up to several megapixels in the case of both OF sensors and celestial compasses).,"This helps AntBot get a read of where it is and where it needs to go, just like how early mariners used celestial compasses. These scattered lights are symmetric when compared to the location of the sun, which is why ants can use them to get their orientation while navigating. Aside from using its light sensors, AntBot can also measure the number of steps it has already taken to determine its movement rate relative to where the sun is.","The stride information can also be used to reliably determine the robot's heading (modes PI-OF-ST and PI-ST-FUSE). AntBot's navigation performances involved a very small number of pixels in comparison with traditional engineering solutions (up to several megapixels in the case of both OF sensors and celestial compasses). Because of the robot's walking and turning limitations (maximum walking stride, 8.2 cm; maximum turning stride, 10.9°), this criterion was a fair compromise between AntBot's possibilities and the requirements of the homing task.","[4.0, 3.0, 4.0, 4.0, 1.0]",Computer_Science,test,3.2,news,http://ct.moreover.com/?a=39344349534&p=1pl&v=1&x=BFijlzCLzbVSdYcufLXxTA 10.1126/sciadv.1500047,Computer_Science_563,This means that it will detect planets that don't take long to orbit their stars and so will produce several transits while TESS is looking at them.,"One path forward is to continue the modeling approach with biofluxes as free ranging parameters and detailed photochemistry models while considering planets more and more different from Earth, no matter how vast the parameter space of imagined scenarios might be.","It should find the small, rocky planets that Kepler proved are abundant but find them orbiting stars that are bright enough for us to study their atmospheres with JWST. This means that it will detect planets that don't take long to orbit their stars and so will produce several transits while TESS is looking at them. Planets with short orbits are located close to their stars, meaning that most planets TESS finds will be too hot for liquid water.","There are two separate but related paths forward. One path forward is to continue the modeling approach with biofluxes as free ranging parameters and detailed photochemistry models while considering planets more and more different from Earth, no matter how vast the parameter space of imagined scenarios might be. This exhaustive modeling endeavor has inadvertently begun for O 2 , with the resurgent consideration of false positives and different possibilities in terms of atmospheric mantle, surface and atmospheric chemistry, and photochemistry scenarios.","[3.0, 3.0, 1.0, 2.0, 1.0]",Computer_Science,test,2.0,news,http://ct.moreover.com/?a=33796665656&p=1pl&v=1&x=xyKLzFVIssMlBOJCXUIWwg 10.1073/pnas.1800083115,Computer_Science_564,"From 1950 onward, however, artists appeared to return to ordered ideals, embracing clean lines and neat grids to an extent surpassing that of their Renaissance and Romanticism predecessors.","By calculating two complexity measures associated with the local order of the pixel arrangement in these artworks, we observe a clear and robust temporal evolution.","The final data pool spanned more than 2,000 artists and 100 styles. From 1950 onward, however, artists appeared to return to ordered ideals, embracing clean lines and neat grids to an extent surpassing that of their Renaissance and Romanticism predecessors. Paintings with highly variable patterns were viewed as more complex, while those with relative uniformity were deemed less complex.","and showed also that the same quantity can be used to capture information about artistic styles. By calculating two complexity measures associated with the local order of the pixel arrangement in these artworks, we observe a clear and robust temporal evolution. This evolution is characterized with transitions that agree with different art periods.","[3.0, 3.0, 2.0, 4.0]",Computer_Science,test,3.0,news,http://ct.moreover.com/?a=38738214972&p=1pl&v=1&x=cspTabP7hhsez5Htg_hY0A 10.26615/978-954-452-049-6_045,Computer_Science_570,Ghulati insisted that the data wouldn't be biased towards a platform or a brand--it would simply provide the information for investors or advertisers to make up their own minds.,"We can see that, among the hand-crafted features, the lexical features yield the best results, i.e., words are the most indicative features.","When advertising platforms were inadvertently creating an incentive for made-up content by allowing anyone to make money from adverts on content regardless of whether it was made up, it made sense to fix that unintended consequence."" Ghulati insisted that the data wouldn't be biased towards a platform or a brand--it would simply provide the information for investors or advertisers to make up their own minds. Babakar said that this could be a realistic way of limiting distribution of very low quality content, by acting as a ""spam filter.""","SVMs have proven to perform well in different classification settings, including in the case of small and noisy datasets. We can see that, among the hand-crafted features, the lexical features yield the best results, i.e., words are the most indicative features. The good results of the stylometric features indicate that the intricacies of language use are highly discriminative.","[2.0, 2.0, 2.0, 2.0]",Computer_Science,test,2.0,news,http://ct.moreover.com/?a=34341934035&p=1pl&v=1&x=CSmSqTTBxUqzhgQ8EmFx2A 10.1145/2702123.2702397,Computer_Science_59,"The final analysis shows that the mixed-reality game improved learning by almost five times more than the screen-only alternatives, both in the mouse-controlled and physically controlled conditions.",This suggests that having a character in the game made it more engaging and memorable for children.,"A game that combined real-world experiments with interactions on a computer tablet improved learning by almost five times more than screen-only alternatives. The final analysis shows that the mixed-reality game improved learning by almost five times more than the screen-only alternatives, both in the mouse-controlled and physically controlled conditions. Not only that, but students enjoyed the game more in the mixed-reality conditions.","In addition, children mentioned that they liked the gorilla character in the game, telling their friends about their gorilla friend. This suggests that having a character in the game made it more engaging and memorable for children. Our experimental results provide evidence that observing physical phenomena in the context of an interactive mixedreality game plays an important role for learning and enjoyment, while adding simple physical controls such as having the kids shake the tablet in a screen-only game or press the physical switch in a mixed-reality game does not have an effect on learning or enjoyment.","[1.0, 1.0, 1.0, 2.0]",Computer_Science,test,1.25,news,http://www.theepochtimes.com/n3/1354229-why-tablets-cant-replace-real-world-schools/ 10.1073/pnas.1309160110,Computer_Science_593,"If you're reading this article, you are almost certainly a user of the decimal system.","And second, even in a preliterate society like Mangareva, the frequent exchange of goods by way of tributes and redistribution within 14, and beyond island boundaries generates a need for the aforementioned operations at least to some extent.","Perhaps far older than the invention of computers or even the invention of binary math in the West. If you're reading this article, you are almost certainly a user of the decimal system. Some Australian aboriginal groups may have used base-5.","First, addition and multiplication are already inherent in number word construction. And second, even in a preliterate society like Mangareva, the frequent exchange of goods by way of tributes and redistribution within 14, and beyond island boundaries generates a need for the aforementioned operations at least to some extent. Once this sequence is in place, abbreviation strategies lead almost automatically to certain types of basic arithmetic.","[1.0, 1.0, 1.0, 1.0]",Computer_Science,test,1.0,news,http://news.sciencemag.org/archaeology/2013/12/polynesians-may-have-invented-binary-math 10.1145/2702123.2702397,Computer_Science_66,"The final analysis shows that the mixed-reality game improved learning by almost five times more than the screen-only alternatives, both in the mouse-controlled and physically controlled conditions.","On the other hand, integrating simple physical controls such as shaking the tablet has little effect.","A game that combined real-world experiments with interactions on a computer tablet improved learning by almost five times more than screen-only alternatives. The final analysis shows that the mixed-reality game improved learning by almost five times more than the screen-only alternatives, both in the mouse-controlled and physically controlled conditions. Not only that, but students enjoyed the game more in the mixed-reality conditions.","We provided evidence that experiencing physical phenomena accompanied by interactive feedback via depth camera sensing in the real world improves learning (by approximately 5 times compared to a solely screen-based environment), while also enhancing enjoyment significantly. On the other hand, integrating simple physical controls such as shaking the tablet has little effect. Thus, mixed-reality games that support physical observation in the real world have a great potential to enhance learning and enjoyment for young children.","[2.0, 3.0, 2.0, 1.0, 4.0]",Computer_Science,test,2.4,news,http://www.theepochtimes.com/n3/1354229-why-tablets-cant-replace-real-world-schools/ 10.1126/science.aao4408,Computer_Science_71,"But by weighing in specific details about the refugees and the communities where they are headed, the algorithm can place them where their skills are the most marketable.",Various mapping functions can be used.,"The algorithm takes into account a variety of factors that resettlement agencies usually don't, from age to English proficiency to the size of the immigrant community from a refugee's country in any given location. But by weighing in specific details about the refugees and the communities where they are headed, the algorithm can place them where their skills are the most marketable. In the US, chances of finding work rose to 50% with the algorithm, for the median refugee.","A separate model was fit for subgroups of refugees assigned to each location, thus yielding different models for each location and allowing for the discovery of refugee/location synergies. Various mapping functions can be used. Our preferred case-level metric was the predicted probability that at least one refugee in the case would find employment at the location in question.","[1.0, 1.0, 1.0, 1.0, 1.0]",Computer_Science,test,1.0,news,http://ct.moreover.com/?a=33043872014&p=1pl&v=1&x=ioHTDQjI3HcfKMxGI9-OBQ 10.1145/2702123.2702397,Computer_Science_73,"They plan to extend their mixed-reality game to different content areas to create a new educational system that bridges the advantages of physical and virtual worlds to improve children's science learning, understanding and enjoyment in a collaborative way.","In future work, we aim to explore the role of combining more handson activities while maintaining the vision-based interactive learning feedback.","They also determined that simple physical controls like shaking the tablet or pushing the earthquake button did little to improve either learning or enjoyment of the game. ""Mixed-reality games that support physical observation in the real world have a great potential to enhance learning and enjoyment for young children,"" the researchers say. They plan to extend their mixed-reality game to different content areas to create a new educational system that bridges the advantages of physical and virtual worlds to improve children's science learning, understanding and enjoyment in a collaborative way.","Children's comments and our survey data suggest that having more building activities integrated into the game can make it more enjoyable for children. In future work, we aim to explore the role of combining more handson activities while maintaining the vision-based interactive learning feedback. We also aim to expand our mixed-reality game for different content areas in education (e.g., using a balance scale rather than earthquake table) to test the generalizability of our results.","[3.0, 4.0, 4.0, 2.0]",Computer_Science,test,3.25,news,http://www.theepochtimes.com/n3/1354229-why-tablets-cant-replace-real-world-schools/ 10.1145/2702123.2702397,Computer_Science_74,A game that combined real-world experiments with interactions on a computer tablet improved learning by almost five times more than screen-only alternatives.,A general implication for educational game design is that affording physical observation in the real world accompanied by real-time interactive feedback may be more important than affording simple hands-on control on a tablet.,"A game that combined real-world experiments with interactions on a computer tablet improved learning by almost five times more than screen-only alternatives. The final analysis shows that the mixed-reality game improved learning by almost five times more than the screen-only alternatives, both in the mouse-controlled and physically controlled conditions. Not only that, but students enjoyed the game more in the mixed-reality conditions.","Our 2x2 experiment found no evidence that adding simple forms of hands-on control enhances learning, while demonstrating a large impact of physical observation. A general implication for educational game design is that affording physical observation in the real world accompanied by real-time interactive feedback may be more important than affording simple hands-on control on a tablet. Utilizing computer-vision technology to provide welldesigned interactive feedback to children while they interact with physical objects in their everyday environment may be an engaging and powerful way to learn .","[3.0, 3.0, 2.0, 4.0]",Computer_Science,test,3.0,news,http://www.theepochtimes.com/n3/1354229-why-tablets-cant-replace-real-world-schools/ 10.1126/science.aao4408,Computer_Science_77,It turned out that refugees with particular backgrounds or skills achieved better outcomes in some locations than others.,The results from these tests all show considerable gains.,"They found that the refugees' eventual economic self-sufficiency depended on a combination of their individual characteristics, such as education level and knowledge of English, and where they were resettled within the country. It turned out that refugees with particular backgrounds or skills achieved better outcomes in some locations than others. The algorithm assigned placements for refugees that they project would increase their chances of finding employment by roughly 40 to 70 percent compared with how the refugees actually fared, according to the new study, published in Science.","These results suggest that the data-driven assignment has the potential to increase third-year employment in the Swiss context by about 73%. The results from these tests all show considerable gains. Our analysis demonstrated large potential improvements, but we did not test the algorithm prospectively.","[1.0, 4.0, 2.0, 1.0]",Computer_Science,test,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/ycYLqg96qto/ 10.1126/science.aao4408,Computer_Science_78,"They found that the refugees' eventual economic self-sufficiency depended on a combination of their individual characteristics, such as education level and knowledge of English, and where they were resettled within the country.",The results from these tests all show considerable gains.,"They found that the refugees' eventual economic self-sufficiency depended on a combination of their individual characteristics, such as education level and knowledge of English, and where they were resettled within the country. It turned out that refugees with particular backgrounds or skills achieved better outcomes in some locations than others. The algorithm assigned placements for refugees that they project would increase their chances of finding employment by roughly 40 to 70 percent compared with how the refugees actually fared, according to the new study, published in Science.","These results suggest that the data-driven assignment has the potential to increase third-year employment in the Swiss context by about 73%. The results from these tests all show considerable gains. Our analysis demonstrated large potential improvements, but we did not test the algorithm prospectively.","[3.0, 1.0, 1.0, 2.0, 1.0]",Computer_Science,test,1.6,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/ycYLqg96qto/ 10.1126/science.aao4408,Computer_Science_86,"In other words, the locations and the number of refugees remain the same, they are just matched more precisely and systematically.",This indicates that there are synergies between places and people; certain characteristics will make a refugee a better match for a particular location.,"Canton Actual With algorithm OW 0% 40% TI 4% 32% FR 4% 15% LU 7% 18% VS 7% 14% VD 8% 8% BL 11% 12% AG 11% 21% GE 13% 23% ZH 15% 7% BE 16% 35% JU 17% 21% SG 17% 28% SH 20% 51% UR 20% 48% ZG 20% 61% GL 22% 42% BS 25% 25% NE 25% 11% SO 25% 64% GR 29% 64% NW 29% 45% SZ 29% 18% TG 30% 33% AR 33% 46% Here's roughly how the algorithm works: The process starts with a series of models trained to predict where a certain type of refugee is likely to fare best based on previous cases. In other words, the locations and the number of refugees remain the same, they are just matched more precisely and systematically. ""It's really hard for a human to juggle all of those.""","Finally, the expected employment returns associated with personal characteristics can vary across different resettlement locations (Fig. This indicates that there are synergies between places and people; certain characteristics will make a refugee a better match for a particular location. In Switzerland, for example, we find that the ability to speak French (i.e., among French-speaking African refugees) results in a larger payoff for refugees assigned to Frenchspeaking cantons than for those assigned to German-speaking cantons ( fig.","[5.0, 4.0, 2.0, 4.0, 5.0]",Computer_Science,test,4.0,news,http://ct.moreover.com/?a=33043872014&p=1pl&v=1&x=ioHTDQjI3HcfKMxGI9-OBQ 10.1126/science.aao4408,Computer_Science_91,"The more successful refugees are where they settle, the more welcoming locals are likely to be in the future.",This indicates that there are synergies between places and people; certain characteristics will make a refugee a better match for a particular location.,"Aside from improving individual lives, machine matching also has the potential of helping refugees overall. The more successful refugees are where they settle, the more welcoming locals are likely to be in the future. The researchers' team is in talks with resettlement agencies in both the US and Switzerland to test the algorithm in pilot programs with actual cases.","Finally, the expected employment returns associated with personal characteristics can vary across different resettlement locations (Fig. This indicates that there are synergies between places and people; certain characteristics will make a refugee a better match for a particular location. In Switzerland, for example, we find that the ability to speak French (i.e., among French-speaking African refugees) results in a larger payoff for refugees assigned to Frenchspeaking cantons than for those assigned to German-speaking cantons ( fig.","[3.0, 2.0, 5.0, 5.0, 2.0]",Computer_Science,test,3.0,news,http://ct.moreover.com/?a=33043872014&p=1pl&v=1&x=ioHTDQjI3HcfKMxGI9-OBQ 10.1126/science.aao4408,Computer_Science_94,"The algorithm assigned placements for refugees that they project would increase their chances of finding employment by roughly 40 to 70 percent compared with how the refugees actually fared, according to the new study in Science.",The results from these tests all show considerable gains.,"In 2016 alone, about 65.6 million people were forced to flee their homes. The algorithm assigned placements for refugees that they project would increase their chances of finding employment by roughly 40 to 70 percent compared with how the refugees actually fared, according to the new study in Science. The group, from Stanford and ETH Zurich, says the algorithm, which could be implemented at virtually no cost, could help resource-constrained governments and resettlement agencies find the best places for refugees to relocate.","These results suggest that the data-driven assignment has the potential to increase third-year employment in the Swiss context by about 73%. The results from these tests all show considerable gains. Our analysis demonstrated large potential improvements, but we did not test the algorithm prospectively.","[2.0, 1.0, 2.0, 1.0, 2.0]",Computer_Science,test,1.6,news,http://www.futurity.org/refugee-resettlement-algorithm-1658522-2/ 10.1145/2702123.2702397,Computer_Science_95,"[related] The final analysis shows that the mixed-reality game improved learning by almost five times more than the screen-only alternatives, both in the mouse-controlled and physically controlled conditions.","Our experimental results provide evidence that observing physical phenomena in the context of an interactive mixedreality game plays an important role for learning and enjoyment, while adding simple physical controls such as having the kids shake the tablet in a screen-only game or press the physical switch in a mixed-reality game does not have an effect on learning or enjoyment.","[related] The final analysis shows that the mixed-reality game improved learning by almost five times more than the screen-only alternatives, both in the mouse-controlled and physically controlled conditions. Not only that, but students enjoyed the game more in the mixed-reality conditions. They also determined that simple physical controls like shaking the tablet or pushing the earthquake button did little to improve either learning or enjoyment of the game.","This suggests that having a character in the game made it more engaging and memorable for children. Our experimental results provide evidence that observing physical phenomena in the context of an interactive mixedreality game plays an important role for learning and enjoyment, while adding simple physical controls such as having the kids shake the tablet in a screen-only game or press the physical switch in a mixed-reality game does not have an effect on learning or enjoyment. The results revealed that even for this subset there was still a significant effect of mixed reality (over virtual) on learning (p<0.01).","[4.0, 4.0, 3.0, 4.0]",Computer_Science,test,3.75,news,http://www.futurity.org/tablets-real-world-learning-917682/ 10.1007/s00799-012-0092-1,Computer_Science_tweet_103,DANS has been analysing it’s costs to understand what to charge and how - #eudatc2 #jiscmrd #ukdcc,Relevance of the developed cost model to the reality of the archiving practices in the organisation ensures understanding of the model by employees and managers.,DANS has been analysing it’s costs to understand what to charge and how - #eudatc2 #jiscmrd #ukdcc,"Of major importance are also characteristics like relevance, accuracy and usability. Relevance of the developed cost model to the reality of the archiving practices in the organisation ensures understanding of the model by employees and managers. They all have added much to our understanding of the factors affecting a cost model in this field .","[2.0, 2.0, 2.0, 1.0]",Computer_Science,test,1.75,tweets,395475567429963778 10.1287/isre.1100.0339,Computer_Science_tweet_109,"RT @username: ""Social Networks & diffusion of User-Generated Content: Evidence from YouTube"" latest issue of ISR. ","If the process of information transmission does not depend on user tastes or homophily, we should observe that the impact of the originating channel's position in the friend network and subscriber networks should be similar throughout the diffusion process.","RT @username: ""Social Networks & diffusion of User-Generated Content: Evidence from YouTube"" latest issue of ISR. ","Within-group friends' influence is greater friend networks, creating a social multiplier effect that magnifies the impact of user tastes through social preferences such as conformity. If the process of information transmission does not depend on user tastes or homophily, we should observe that the impact of the originating channel's position in the friend network and subscriber networks should be similar throughout the diffusion process. We also find that the impact of nonlocal ties is stronger in the process of diffusion than that of within-group ties.","[1.0, 3.0, 3.0, 1.0]",Computer_Science,test,2.0,tweets,180064896338243584 10.1073/pnas.1405698111,Computer_Science_tweet_116,Bacteria’s tail spins make water droplets swirl ,"These results, consistently found by sampling over 20 cells, confirm the prediction from simulations: while all the bacteria point in the same direction (outward), the bulk microswimmers move overall in a backward fashion, opposite to the boundary layer motion.",Bacteria’s tail spins make water droplets swirl ,"Yet, the relation between the flagella position and the mean membrane position and the flagella bundling at the rear of the bacteria reveal that the cell is pointing to the topleft corner, in a direction opposite to its motion. These results, consistently found by sampling over 20 cells, confirm the prediction from simulations: while all the bacteria point in the same direction (outward), the bulk microswimmers move overall in a backward fashion, opposite to the boundary layer motion. As shown in previous sections, experiments and simulations with both steric and hydrodynamical interactions are in qualitative agreement on both micro-and macroscopic scales.","[1.0, 5.0, 2.0, 4.0]",Computer_Science,test,3.0,tweets,481508077103874048 10.1126/science.aao4408,Computer_Science_tweet_12,Machine learning improves refugee integration ,This indicates that there are synergies between places and people; certain characteristics will make a refugee a better match for a particular location.,Machine learning improves refugee integration ,"Finally, the expected employment returns associated with personal characteristics can vary across different resettlement locations (Fig. This indicates that there are synergies between places and people; certain characteristics will make a refugee a better match for a particular location. In Switzerland, for example, we find that the ability to speak French (i.e., among French-speaking African refugees) results in a larger payoff for refugees assigned to Frenchspeaking cantons than for those assigned to German-speaking cantons ( fig.","[3.0, 3.0, 5.0]",Computer_Science,test,3.6666666666666665,tweets,954103046635737090 10.1287/orsc.2014.0900,Computer_Science_tweet_131,Is it worse to receive negative attention than none at all? Ostracised workers fare worse than harassed workers ,"We believe a sense of belonging will at least partially mediate the relationship between ostracism and employee outcomes because ostracism threatens other psychosocial needs, even if the need to belong is the most fundamental and directly affected of these (cf.",Is it worse to receive negative attention than none at all? Ostracised workers fare worse than harassed workers ,"Employees' sense of belonging at least partially mediates the relationships between ostracism and their (a) personal well-being, (b) work-related attitudes, and (c) turnover. We believe a sense of belonging will at least partially mediate the relationship between ostracism and employee outcomes because ostracism threatens other psychosocial needs, even if the need to belong is the most fundamental and directly affected of these (cf. A total of 146 participants opened the link to the survey, of which 100 were completed (44% male; mean age in years = 32.64, S.D.","[4.0, 2.0, 4.0, 5.0, 1.0]",Computer_Science,test,4.0,tweets,453111296863395840 10.1126/science.aao4408,Computer_Science_tweet_142,Interesting--machine learning algorithm to assist with refugee resettlement. ,"Finally, the expected employment returns associated with personal characteristics can vary across different resettlement locations (Fig.",Interesting--machine learning algorithm to assist with refugee resettlement. ,"In addition, refugees with certain characteristics, such as language and educational skills, are more likely to succeed economically regardless of the resettlement location to which they are sent (Fig. Finally, the expected employment returns associated with personal characteristics can vary across different resettlement locations (Fig. This indicates that there are synergies between places and people; certain characteristics will make a refugee a better match for a particular location.","[1.0, 3.0, 2.0, 2.0]",Computer_Science,test,2.0,tweets,954100198241984514 10.1038/s41467-018-06930-7,Computer_Science_tweet_150,The spread of fake news by social bots ,Relatively few accounts are responsible for a large share of the traffic that carries misinformation.,The spread of fake news by social bots ,"Our analysis provides quantitative empirical evidence of the key role played by social bots in the viral spread of fake news online. Relatively few accounts are responsible for a large share of the traffic that carries misinformation. These accounts are likely bots, and we uncovered several manipulation strategies they use.","[2.0, 5.0, 3.0, 4.0]",Computer_Science,test,3.5,tweets,894737009989648384 10.1038/nature15693,Computer_Science_tweet_165,Only combined activity of Cerebellar burst and pause cells predicts saccadic eye movements: ,"We found that if we organized the simple spikes of the Purkinje cells based on each cell's complex-spike properties, additional features of the population activity were unmasked.",Only combined activity of Cerebellar burst and pause cells predicts saccadic eye movements: ,"The input from the olive produces complex spikes in the Purkinje cells. We found that if we organized the simple spikes of the Purkinje cells based on each cell's complex-spike properties, additional features of the population activity were unmasked. Figure 3b shows the change in population response from the baseline level when a saccade was made in the same direction as CS-off.","[2.0, 2.0, 2.0, 2.0]",Computer_Science,test,2.0,tweets,654664621542928384 10.1126/scirobotics.aat5643,Computer_Science_tweet_178,Microhydraulic actuators consist of thin layers of solid sheets separated by fluidic drops and move these layers relative to each other by internally modifying surface energy with electrowetting. They borrow in form and... ,This results in a quadratic increase in force density as dimensions are reduced.,Microhydraulic actuators consist of thin layers of solid sheets separated by fluidic drops and move these layers relative to each other by internally modifying surface energy with electrowetting. They borrow in form and... ,"Scaling to smaller dimensions: Force, power, and efficiency Increasing the power density of microhydraulic actuators is straightforward: Decreasing droplet pitch and height reduces the droplet mass per width quadratically, whereas force per droplet width stays constant, at approximately the surface tension. This results in a quadratic increase in force density as dimensions are reduced. The actuation velocity stays roughly constant, because the increased force is counterbalanced by increased viscous losses.","[5.0, 4.0, 1.0, 2.0, 1.0]",Computer_Science,test,1.0,tweets,1042773003589697536 10.1073/pnas.1309160110,Computer_Science_tweet_181,"Mangarevan #invention of #binary steps for easier #calculation #Beller and #Bender on #PNAS ","And second, even in a preliterate society like Mangareva, the frequent exchange of goods by way of tributes and redistribution within 14, and beyond island boundaries generates a need for the aforementioned operations at least to some extent.","Mangarevan #invention of #binary steps for easier #calculation #Beller and #Bender on #PNAS ","First, addition and multiplication are already inherent in number word construction. And second, even in a preliterate society like Mangareva, the frequent exchange of goods by way of tributes and redistribution within 14, and beyond island boundaries generates a need for the aforementioned operations at least to some extent. Once this sequence is in place, abbreviation strategies lead almost automatically to certain types of basic arithmetic.","[2.0, 2.0, 2.0, 1.0]",Computer_Science,test,1.75,tweets,437204160971558912 10.1073/pnas.1719233115,Computer_Science_tweet_193,"Finally! Our paper on how our cognitive capabilities structure our friendships is out in @username (Open Access). With special thanks to @username, who provided the data on inmigrant communities that confirmed the new regime predicted by our theory! ","More interestingly, it predicts that when the number of available relationships is small, this structure is inverted, having more close relationships than acquaintances.","Finally! Our paper on how our cognitive capabilities structure our friendships is out in @username (Open Access). With special thanks to @username, who provided the data on inmigrant communities that confirmed the new regime predicted by our theory! ","Of itself, this distribution yields no structure whatsoever but it is a reasonable More interestingly, it predicts that when the number of available relationships is small, this structure is inverted, having more close relationships than acquaintances. We provide evidence of the existence of both regimes in real communities and analyze the consequences of these findings in our understanding of social groups.","[4.0, 4.0, 1.0, 3.0, 1.0]",Computer_Science,test,1.0,tweets,1022736157342347270 10.1073/pnas.1719233115,Computer_Science_tweet_199,"Further (subjective, but suggestive) evidence supporting our ""inverted regime"" of friendship distribution (most very good friends, but not many overall) predicted in our paper … from @username writing in @username … ","Since these technologies reduce the effective cost of maintaining some relationships, it should be easier for individuals to establish larger networks and this should promote the standard regime.","Further (subjective, but suggestive) evidence supporting our ""inverted regime"" of friendship distribution (most very good friends, but not many overall) predicted in our paper … from @username writing in @username … ","More interestingly, perhaps, our model predicts how the increasing availability of online social networks may affect the way we handle our relationships. Since these technologies reduce the effective cost of maintaining some relationships, it should be easier for individuals to establish larger networks and this should promote the standard regime. However, if online relationships are cheaper to maintain because they obviate the costly business of physically meeting up with an alter , it follows that any increase in online network size will be associated with a reduction in average tie strength.","[4.0, 1.0, 3.0, 2.0]",Computer_Science,test,2.5,tweets,1024204407473405952 10.1145/2702123.2702397,Computer_Science_tweet_200,'Physical observation + interactive feedback improved children’s learning by 5x' via Nesra Yannier @username ,"These results show that mixed-reality led to more learning than screen only, for both the mousecontrol and physical-control conditions ( Figure 10 ).",'Physical observation + interactive feedback improved children’s learning by 5x' via Nesra Yannier @username ,"There was no effect of control type and no interaction effects. These results show that mixed-reality led to more learning than screen only, for both the mousecontrol and physical-control conditions ( Figure 10 ). We can consider what choice improves learning most over a typical virtual, mouse-control game (#1 in Figure 10 ).","[5.0, 2.0, 1.0]",Computer_Science,test,4.0,tweets,611294107672125442 10.1098/rsif.2014.0623,Computer_Science_tweet_243,"First Bitcoin paper out! My first paper as last author, too. Cool. Warning: may contain crazy stats","The VAR reveals the following feedback cycles: -'social' cycle: search volume increases with price (f P,S ¼ 0.386), word of mouth increases with search volume (f S,W ¼ 0.243), and price increases with word of mouth (f W,P ¼ 0.1).","First Bitcoin paper out! My first paper as last author, too. Cool. Warning: may contain crazy stats","In this statistical model, the change in each variable on a given day fDU t , DP t , DS t , DW t g is a linear combination of the changes in all variables fDU t21 , DP t21 , DS t21 , DW t21 g on the previous day, including a deterministic, a periodic and an error term . The VAR reveals the following feedback cycles: -'social' cycle: search volume increases with price (f P,S ¼ 0.386), word of mouth increases with search volume (f S,W ¼ 0.243), and price increases with word of mouth (f W,P ¼ 0.1). Simultaneously accounting for all dependencies between the four variables emphasizes the influence of word of mouth on price, revealing a stronger relation than cannot be observed with pairwise correlation analysis (more details in the electronic supplementary material, §S3).","[1.0, 1.0, 1.0]",Computer_Science,test,1.0,tweets,497033403137802240 10.1038/srep04001,Computer_Science_tweet_281,"The emergence and role of strong ties in time-varying communication networks ","In the long run the system always reaches an equilibrium state where all spreaders have turned into stiflers, ∂ t i(t) = 0, and ∂ t r(t) = 0.","The emergence and role of strong ties in time-varying communication networks ","We assume that only their ratio matters for the spreading behaviour (supporting results are summarized in SM). In the long run the system always reaches an equilibrium state where all spreaders have turned into stiflers, ∂ t i(t) = 0, and ∂ t r(t) = 0. Different parameters provide different penetration of the rumor in the network.","[1.0, 3.0, 2.0]",Computer_Science,test,2.0,tweets,316600252348133376 10.1073/pnas.1800083115,Computer_Science_tweet_284,Great to see more humanities-related studies in places like PNAS! ,"By calculating two complexity measures associated with the local order of the pixel arrangement in these artworks, we observe a clear and robust temporal evolution.",Great to see more humanities-related studies in places like PNAS! ,"and showed also that the same quantity can be used to capture information about artistic styles. By calculating two complexity measures associated with the local order of the pixel arrangement in these artworks, we observe a clear and robust temporal evolution. This evolution is characterized with transitions that agree with different art periods.","[1.0, 1.0, 2.0, 1.0]",Computer_Science,test,1.25,tweets,1036257283246833664 10.1140/epjds/s13688-017-0110-z,Computer_Science_tweet_289,How interesting: Instagram photos reveal early signs of #depression #DataScience,"Our results supported Hypothesis , that markers of depression are observable in Instagram user behavior, and Hypothesis , that these depressive signals are detectable in posts made even before the date of first diagnosis.",How interesting: Instagram photos reveal early signs of #depression #DataScience,"The modest positive correlation of human-rated happiness with the presence and number of faces in a photograph was the only exception to this trend. Our results supported Hypothesis , that markers of depression are observable in Instagram user behavior, and Hypothesis , that these depressive signals are detectable in posts made even before the date of first diagnosis. Human ratings proved capable of distinguishing between Instagram posts made by depressed and healthy individuals (Hypothesis a), but showed little or no correlation with most computational features (Hypothesis b).","[4.0, 4.0, 5.0]",Computer_Science,test,4.333333333333333,tweets,898528515720654849 10.1140/epjds/s13688-017-0110-z,Computer_Science_tweet_296,"Machine learns to diagnose depression better than doctors…based on patients' Instagram photos. ","Our results supported Hypothesis , that markers of depression are observable in Instagram user behavior, and Hypothesis , that these depressive signals are detectable in posts made even before the date of first diagnosis.","Machine learns to diagnose depression better than doctors…based on patients' Instagram photos. ","The modest positive correlation of human-rated happiness with the presence and number of faces in a photograph was the only exception to this trend. Our results supported Hypothesis , that markers of depression are observable in Instagram user behavior, and Hypothesis , that these depressive signals are detectable in posts made even before the date of first diagnosis. Human ratings proved capable of distinguishing between Instagram posts made by depressed and healthy individuals (Hypothesis a), but showed little or no correlation with most computational features (Hypothesis b).","[3.0, 3.0, 1.0]",Computer_Science,test,2.333333333333333,tweets,899583907577901056 10.1126/scirobotics.aau0275,Computer_Science_tweet_31,New #robotic #origami by @username researchers mimics dual softness and stiffness of insect wings: ,"Furthermore, in addition to load bearing and crash resilience, the compliant origami also stored elastic energy that can be leveraged for self-deployment of the drone from a folded configuration.",New #robotic #origami by @username researchers mimics dual softness and stiffness of insect wings: ,"The origami structure described here achieved similar performance with a scalable, rapid, and cost-effective manufacturing process. Furthermore, in addition to load bearing and crash resilience, the compliant origami also stored elastic energy that can be leveraged for self-deployment of the drone from a folded configuration. When the arms buckle due to a horizontal flexural load, the apex angle collapsed, and the arm can be wrapped around the main frame by folding along the transversal folds (Fig.","[2.0, 5.0, 4.0, 3.0, 2.0]",Computer_Science,test,3.2,tweets,1022191156430610433 10.1287/mnsc.2014.2115,Computer_Science_tweet_5,"Researchers say 120,000 deaths a yr may be from stress related to the way U.S. companies manage their work forces: ","We find that more than 120,000 deaths per year and approximately 5-8% of annual healthcare costs are associated with and may be attributable to how U.S. companies manage their work force.","Researchers say 120,000 deaths a yr may be from stress related to the way U.S. companies manage their work forces: ","Specifically, the model separately derives optimistic and conservative estimates of the effect of multiple workplace exposures on health, and uses optimization to calculate upper and lower bounds around each estimate, which accounts for the correlation between exposures. We find that more than 120,000 deaths per year and approximately 5-8% of annual healthcare costs are associated with and may be attributable to how U.S. companies manage their work force. Our results suggest that more attention should be paid to management practices as important contributors to health outcomes and costs in the U.S..","[5.0, 4.0, 5.0, 5.0]",Computer_Science,test,4.75,tweets,582940664285044736 10.1145/2702123.2702397,Computer_Science_tweet_50,"Mixed reality variations improve learning, over screen-only options. CMU researchers. ",The overall improvement from pre to post was 11.3 % in the mixed-reality conditions and 2.4 % in the virtual conditions.,"Mixed reality variations improve learning, over screen-only options. CMU researchers. ","The overall results (including both the prediction and explanation items) indicated that there was a significant effect of media-type (F(1,91)=8.2, p<0.01, d=0.37). The overall improvement from pre to post was 11.3 % in the mixed-reality conditions and 2.4 % in the virtual conditions. Thus, the mixed-reality game improved learning by 4.8 times compared to the screen-only alternatives.","[2.0, 5.0, 3.0]",Computer_Science,test,5.0,tweets,602858114749177856 10.1126/science.aao4408,Computer_Science_tweet_52,"""We developed a flexible data-driven algorithm that assigns refugees across resettlement locations."" ""This approach can provide governments with a practical and cost-efficient policy tool that can be immediately implemented within existing institutional structures."" ",Our preferred case-level metric was the predicted probability that at least one refugee in the case would find employment at the location in question.,"""We developed a flexible data-driven algorithm that assigns refugees across resettlement locations."" ""This approach can provide governments with a practical and cost-efficient policy tool that can be immediately implemented within existing institutional structures."" ",Various mapping functions can be used. Our preferred case-level metric was the predicted probability that at least one refugee in the case would find employment at the location in question. Our algorithm is flexible and can accommodate multiple criteria and constraints.,"[2.0, 2.0, 3.0, 3.0]",Computer_Science,test,2.5,tweets,954181740905431040 10.1126/science.aao4408,Computer_Science_tweet_54,"Interesting to see how the local communities react to this algorithm, esp given that refugees are thought to be increasing competition over jobs. ","Our approach led to gains of roughly 40 to 70%, on average, in refugees' employment outcomes relative to current assignment practices.","Interesting to see how the local communities react to this algorithm, esp given that refugees are thought to be increasing competition over jobs. ","Our approach led to gains of roughly 40 to 70%, on average, in refugees' employment outcomes relative to current assignment practices. This approach can provide governments with a practical and cost-efficient policy tool that can be immediately implemented within existing institutional structures. It is also one of the most consequential in maximizing refugees' economic integration and self-sufficiency as a first step toward a more comprehensive integration into society (7-9).","[2.0, 3.0, 3.0]",Computer_Science,test,2.6666666666666665,tweets,954075502498676736 10.1126/science.aao4408,Computer_Science_tweet_55,"“Harnessing Big Data to Improve Refugee Resettlement” by @username @username The underlying research in @username: via @username","In addition, refugees with certain characteristics, such as language and educational skills, are more likely to succeed economically regardless of the resettlement location to which they are sent (Fig.","“Harnessing Big Data to Improve Refugee Resettlement” by @username @username The underlying research in @username: via @username","It is also one of the most consequential in maximizing refugees' economic integration and self-sufficiency as a first step toward a more comprehensive integration into society (7) (8) (9) . In addition, refugees with certain characteristics, such as language and educational skills, are more likely to succeed economically regardless of the resettlement location to which they are sent (Fig. Finally, the expected employment returns associated with personal characteristics can vary across different resettlement locations (Fig.","[2.0, 2.0, 5.0]",Computer_Science,test,2.0,tweets,954093751533817858 10.1126/science.aao4408,Computer_Science_tweet_56,"New Science paper from @username on a tool to improve integration of #refugees by optimally placing them, ","A separate model was fit for subgroups of refugees assigned to each location, thus yielding different models for each location and allowing for the discovery of refugee/location synergies.","New Science paper from @username on a tool to improve integration of #refugees by optimally placing them, ","In Switzerland, for example, we find that the ability to speak French (i.e., among French-speaking African refugees) results in a larger payoff for refugees assigned to Frenchspeaking cantons than for those assigned to German-speaking cantons ( fig. A separate model was fit for subgroups of refugees assigned to each location, thus yielding different models for each location and allowing for the discovery of refugee/location synergies. Various mapping functions can be used.","[3.0, 3.0, 4.0, 3.0]",Computer_Science,test,3.25,tweets,954183062526492672 10.1073/pnas.1719233115,Computer_Science_tweet_62," the existence of a heterogeneous cost to relationships (in terms of time or cognitive investment), together with a limitation in the total capacity an individual has to invest in them, can naturally explain the existence of layers in social networks","Finally, from a socio-centric perspective, our model suggests a way to identify whether an interconnected set of individuals (i.e., a community in the technical network analysis sense) is ""small"" or not, namely according to the regime of their ego networks."," the existence of a heterogeneous cost to relationships (in terms of time or cognitive investment), together with a limitation in the total capacity an individual has to invest in them, can naturally explain the existence of layers in social networks","This would incentivize weak relationships, which might well be another reason why the inverse regime has remained largely unnoticed until now. Finally, from a socio-centric perspective, our model suggests a way to identify whether an interconnected set of individuals (i.e., a community in the technical network analysis sense) is ""small"" or not, namely according to the regime of their ego networks. In such a setting we find that the change of regime happens at a network size of 88 and that there is a maximum network size of 220 [a value close to the maximum observed network size of ∼250 ].","[1.0, 2.0, 2.0, 3.0, 1.0]",Computer_Science,test,1.8,tweets,1027135117360332805 10.1038/s41746-018-0045-1,Computer_Science_tweet_66,Interesting approach for targeting food inspections ,We used this information to focus restaurant inspections in two cities and demonstrated that FINDER improves the accuracy of health inspections; restaurants identified by FINDER are 3.1 times as likely to be deemed unsafe during the inspection as restaurants identified by existing methods.,Interesting approach for targeting food inspections ,"We used this information to focus restaurant inspections in two cities and demonstrated that FINDER improves the accuracy of health inspections; restaurants identified by FINDER are 3.1 times as likely to be deemed unsafe during the inspection as restaurants identified by existing methods. Additionally, FINDER enables us to ascertain previously intractable epidemiological information, for example, in 38% of cases the restaurant potentially causing food poisoning was not the last one visited, which may explain the lower precision of complaint-based inspections. We found that FINDER is able to reliably identify restaurants that have an active lapse in food safety, allowing for implementation of corrective actions that would prevent the potential spread of foodborne illness.","[3.0, 4.0, 3.0, 4.0]",Computer_Science,test,3.5,tweets,1059843420712263680 10.1145/2702123.2702397,Computer_Science_tweet_87,"@username There's stuff on educational games, and how mixed-reality games > touchscreen, but TV? Can't find it. ","Our experimental results provide evidence that observing physical phenomena in the context of an interactive mixedreality game plays an important role for learning and enjoyment, while adding simple physical controls such as having the kids shake the tablet in a screen-only game or press the physical switch in a mixed-reality game does not have an effect on learning or enjoyment.","@username There's stuff on educational games, and how mixed-reality games > touchscreen, but TV? Can't find it. ","This suggests that having a character in the game made it more engaging and memorable for children. Our experimental results provide evidence that observing physical phenomena in the context of an interactive mixedreality game plays an important role for learning and enjoyment, while adding simple physical controls such as having the kids shake the tablet in a screen-only game or press the physical switch in a mixed-reality game does not have an effect on learning or enjoyment. The results revealed that even for this subset there was still a significant effect of mixed reality (over virtual) on learning (p<0.01).","[3.0, 3.0, 3.0, 5.0, 3.0]",Computer_Science,test,3.4,tweets,840284663528726528 10.1126/scirobotics.aau0307,Computer_Science_tweet_89,@username @username Ant-like polarization and optical flow would be a great addition to Tesla navigation due to it's decentralized and low resource aspect. And doesn't depend on landmark recognition. ,AntBot's navigation performances involved a very small number of pixels in comparison with traditional engineering solutions (up to several megapixels in the case of both OF sensors and celestial compasses).,@username @username Ant-like polarization and optical flow would be a great addition to Tesla navigation due to it's decentralized and low resource aspect. And doesn't depend on landmark recognition. ,"The stride information can also be used to reliably determine the robot's heading (modes PI-OF-ST and PI-ST-FUSE). AntBot's navigation performances involved a very small number of pixels in comparison with traditional engineering solutions (up to several megapixels in the case of both OF sensors and celestial compasses). Because of the robot's walking and turning limitations (maximum walking stride, 8.2 cm; maximum turning stride, 10.9°), this criterion was a fair compromise between AntBot's possibilities and the requirements of the homing task.","[3.0, 3.0, 4.0, 1.0, 3.0]",Computer_Science,test,2.8,tweets,1095773165567979520 10.1126/sciadv.1500047,Computer_Science_tweet_96,Biosignatures Key to Search for Life on Exoplanets via @username @username,"One path forward is to continue the modeling approach with biofluxes as free ranging parameters and detailed photochemistry models while considering planets more and more different from Earth, no matter how vast the parameter space of imagined scenarios might be.",Biosignatures Key to Search for Life on Exoplanets via @username @username,"There are two separate but related paths forward. One path forward is to continue the modeling approach with biofluxes as free ranging parameters and detailed photochemistry models while considering planets more and more different from Earth, no matter how vast the parameter space of imagined scenarios might be. This exhaustive modeling endeavor has inadvertently begun for O 2 , with the resurgent consideration of false positives and different possibilities in terms of atmospheric mantle, surface and atmospheric chemistry, and photochemistry scenarios.","[3.0, 2.0, 3.0, 3.0, 3.0]",Computer_Science,test,2.8,tweets,573926504205271040 10.1073/pnas.1719233115,Computer_Science_easy_1,Some of the most intense friendships I've had to date were during the few years that I lived in an isolated village in rural Alaska.,"1) , and this in turn depends on the total number of social relationships that an individual has.","This is a notion the researchers point out that I can vouch for from personal experience. Some of the most intense friendships I've had to date were during the few years that I lived in an isolated village in rural Alaska. I doubt that I was interacting with over 100 people on a regular basis, but there were at least ten people there that were like family to me at the time.","Hence, which regime an individual belongs to depends on the ratio S /L (Fig. 1) , and this in turn depends on the total number of social relationships that an individual has. If L is large, this structure will be standard.",[1],Computer_Science,test,1.0,news,http://ct.moreover.com/?a=34615793773&p=1pl&v=1&x=B9OeehCkV4Axi__oIw0XTg 10.1073/pnas.1719233115,Computer_Science_easy_2,You could probably extrapolate this effect out to relationships within large or small companies for those of us whose social lives largely overlap with our careers.,2 and 3 ).,"That's probably double what that number has been at any other time in my life. You could probably extrapolate this effect out to relationships within large or small companies for those of us whose social lives largely overlap with our careers. For example, people working in small startups might have a larger number of intense relationships than those in the wider corporate world.","Furthermore, the remaining 25% present values of µ very close to 0, significantly lower than in the case of the community of students (compare Figs. 2 and 3 ). The case of the Bulgarians (Fig.",[1],Computer_Science,test,1.0,news,http://ct.moreover.com/?a=34615793773&p=1pl&v=1&x=B9OeehCkV4Axi__oIw0XTg 10.1145/2702123.2702397,Computer_Science_easy_14,"They plan to extend their mixed-reality game to different content areas to create a new educational system that bridges the advantages of physical and virtual worlds to improve children's science learning, understanding and enjoyment in a collaborative way.","On the other hand, looking at only those interacting with the virtual game, control-type did not have any effect.","They also determined that simple physical controls like shaking the tablet or pushing the earthquake button did little to improve either learning or enjoyment of the game. ""Mixed-reality games that support physical observation in the real world have a great potential to enhance learning and enjoyment for young children,"" the researchers say. They plan to extend their mixed-reality game to different content areas to create a new educational system that bridges the advantages of physical and virtual worlds to improve children's science learning, understanding and enjoyment in a collaborative way.","Thus the physical switch in the mixedreality game was increasing enjoyment slightly. On the other hand, looking at only those interacting with the virtual game, control-type did not have any effect. Children seemed to be very much engaged during the game.",[1],Computer_Science,test,1.0,news,http://www.theepochtimes.com/n3/1354229-why-tablets-cant-replace-real-world-schools/ 10.1073/pnas.1719233115,Computer_Science_easy_15,The same effect can also be found in small communities where are simply fewer options for people to interact with.,This regime is expected to arise when the ratio S /L is particularly large.,The researchers predicted this effect using a mathematical theory and then found that it held true in actual data gathered on the personal networks of isolated immigrant communities in Spain. The same effect can also be found in small communities where are simply fewer options for people to interact with. This is a notion the researchers point out that I can vouch for from personal experience.,"Therefore, a second, as yet unnoticed, regime is predicted in which the structure is reversed-the more demanding the layers, the more populated they are. This regime is expected to arise when the ratio S /L is particularly large. That would be the case, for instance, of individuals living in small populations or within limited social environments.",[1],Computer_Science,test,1.0,news,http://ct.moreover.com/?a=34615793773&p=1pl&v=1&x=B9OeehCkV4Axi__oIw0XTg 10.1126/science.aao4408,Computer_Science_easy_36,They predicted the employment rate would have been 73 percent higher among asylum seekers who arrived in 2013 if they had been assigned to the places the algorithm identified as optimal.,"In Switzerland, for example, we find that the ability to speak French (i.e., among French-speaking African refugees) results in a larger payoff for refugees assigned to Frenchspeaking cantons than for those assigned to German-speaking cantons ( fig.","The group found that if the algorithm had selected locations for refugees' resettlement, the average employment rate among those refugees would have been roughly 41 percent higher. They predicted the employment rate would have been 73 percent higher among asylum seekers who arrived in 2013 if they had been assigned to the places the algorithm identified as optimal. In Vaud, employment prospects are higher for anyone who speaks French.","This indicates that there are synergies between places and people; certain characteristics will make a refugee a better match for a particular location. In Switzerland, for example, we find that the ability to speak French (i.e., among French-speaking African refugees) results in a larger payoff for refugees assigned to Frenchspeaking cantons than for those assigned to German-speaking cantons ( fig. A separate model was fit for subgroups of refugees assigned to each location, thus yielding different models for each location and allowing for the discovery of refugee/location synergies.",[1],Computer_Science,test,1.0,news,http://www.futurity.org/refugee-resettlement-algorithm-1658522-2/ 10.1126/science.aao4408,Computer_Science_easy_48,They predicted the employment rate would have been 73 percent higher among asylum seekers who arrived in 2013 if they had been assigned to the places the algorithm identified as optimal.,"Our approach led to gains of roughly 40 to 70%, on average, in refugees' employment outcomes relative to current assignment practices.","The group found that if the algorithm had selected locations for refugees' resettlement, the average employment rate among those refugees would have been roughly 41 percent higher. They predicted the employment rate would have been 73 percent higher among asylum seekers who arrived in 2013 if they had been assigned to the places the algorithm identified as optimal. In Vaud, employment prospects are higher for anyone who speaks French.","For the algorithm to obtain reliable predictions, it is important that the historical assignment process not be determined by unobserved refugee characteristics. Our approach led to gains of roughly 40 to 70%, on average, in refugees' employment outcomes relative to current assignment practices. This approach can provide governments with a practical and cost-efficient policy tool that can be immediately implemented within existing institutional structures.",[1],Computer_Science,test,1.0,news,http://www.futurity.org/refugee-resettlement-algorithm-1658522-2/ 10.1126/science.aao4408,Computer_Science_easy_64,"The algorithm takes into account a variety of factors that resettlement agencies usually don't, from age to English proficiency to the size of the immigrant community from a refugee's country in any given location.","In Switzerland, for example, we find that the ability to speak French (i.e., among French-speaking African refugees) results in a larger payoff for refugees assigned to Frenchspeaking cantons than for those assigned to German-speaking cantons ( fig.","But what kind of life that will be largely depends on where they end up. The algorithm takes into account a variety of factors that resettlement agencies usually don't, from age to English proficiency to the size of the immigrant community from a refugee's country in any given location. But by weighing in specific details about the refugees and the communities where they are headed, the algorithm can place them where their skills are the most marketable.","This indicates that there are synergies between places and people; certain characteristics will make a refugee a better match for a particular location. In Switzerland, for example, we find that the ability to speak French (i.e., among French-speaking African refugees) results in a larger payoff for refugees assigned to Frenchspeaking cantons than for those assigned to German-speaking cantons ( fig. A separate model was fit for subgroups of refugees assigned to each location, thus yielding different models for each location and allowing for the discovery of refugee/location synergies.",[1],Computer_Science,test,1.0,news,http://ct.moreover.com/?a=33043872014&p=1pl&v=1&x=ioHTDQjI3HcfKMxGI9-OBQ 10.1126/science.aao4408,Computer_Science_easy_67,"""The fact that we are able to generate such significant gains because of a simple change to the resettlement process is a demonstration of just how important it is to bring data-driven insights to policy-making processes,"" Weinstein says.","Our approach led to gains of roughly 40 to 70%, on average, in refugees' employment outcomes relative to current assignment practices.","Yet in contrast to more expensive policy interventions, such as job or language training for refugees, the results of the algorithm, the code of which is available for free to any organization or government, are promising, the researchers say. ""The fact that we are able to generate such significant gains because of a simple change to the resettlement process is a demonstration of just how important it is to bring data-driven insights to policy-making processes,"" Weinstein says. The group says they still need to confirm the algorithm's predictions through prospective tests that implement this approach in real time.","Our approach led to gains of roughly 40 to 70%, on average, in refugees' employment outcomes relative to current assignment practices. This approach can provide governments with a practical and cost-efficient policy tool that can be immediately implemented within existing institutional structures. It is also one of the most consequential in maximizing refugees' economic integration and self-sufficiency as a first step toward a more comprehensive integration into society (7-9).",[1],Computer_Science,test,1.0,news,http://www.futurity.org/refugee-resettlement-algorithm-1658522-2/ 10.1073/pnas.1719233115,Computer_Science_easy_110,"I doubt that I was interacting with over 100 people on a regular basis, but there were at least ten people there that were like family to me at the time.","Note that the name generator used with the groups of immigrants had a limit of 30 names (Materials and Methods), and we nonetheless found both standard and inverse regimes.","Some of the most intense friendships I've had to date were during the few years that I lived in an isolated village in rural Alaska. I doubt that I was interacting with over 100 people on a regular basis, but there were at least ten people there that were like family to me at the time. That's probably double what that number has been at any other time in my life.","This is because imposing a cutoff on a standard network does not change it into an inverse structure: This is clear from Fig. Note that the name generator used with the groups of immigrants had a limit of 30 names (Materials and Methods), and we nonetheless found both standard and inverse regimes. The inverse regime is precisely what we would have expected to emerge in this setting.",[1],Computer_Science,test,1.0,news,http://ct.moreover.com/?a=34615793773&p=1pl&v=1&x=B9OeehCkV4Axi__oIw0XTg 10.1126/science.aao4408,Computer_Science_easy_118,"""The employment gains that we're projecting are quite substantial, and these are gains that could be achieved with almost no additional cost to the governments or resettlement agencies,"" adds Kirk Bansak, a lead author of the study and a political science PhD student at Stanford.","Our approach led to gains of roughly 40 to 70%, on average, in refugees' employment outcomes relative to current assignment practices.","After all, having more refugees employed can also ease the financial burden on the Swiss government, cantons, and municipalities."" ""The employment gains that we're projecting are quite substantial, and these are gains that could be achieved with almost no additional cost to the governments or resettlement agencies,"" adds Kirk Bansak, a lead author of the study and a political science PhD student at Stanford. ""By improving an existing process using existing data, our algorithm avoids many of the financial and administrative hurdles that can often impede other policy innovations.""","For the algorithm to obtain reliable predictions, it is important that the historical assignment process not be determined by unobserved refugee characteristics. Our approach led to gains of roughly 40 to 70%, on average, in refugees' employment outcomes relative to current assignment practices. This approach can provide governments with a practical and cost-efficient policy tool that can be immediately implemented within existing institutional structures.",[1],Computer_Science,test,1.0,news,http://www.futurity.org/refugee-resettlement-algorithm-1658522-2/ 10.1073/pnas.1719233115,Computer_Science_easy_151,Some of the most intense friendships I've had to date were during the few years that I lived in an isolated village in rural Alaska.,Which option an individual opts for may depend on his or her personality [introverts opting for smaller networks ] or on the size of the community he or she happens to be a member of (as seems to be the case here with the immigrant communities where opportunities for social A B C D interaction seem to be restricted to a small number of individuals by social exclusion).,"This is a notion the researchers point out that I can vouch for from personal experience. Some of the most intense friendships I've had to date were during the few years that I lived in an isolated village in rural Alaska. I doubt that I was interacting with over 100 people on a regular basis, but there were at least ten people there that were like family to me at the time.",These inverse structure networks are associated with smaller than usual networks and seem to imply that individuals have a (more or less) fixed quantity of cognitive capital (indexed as time available for investing in alters) which they can spread either thinly among many alters or thickly among fewer alters. Which option an individual opts for may depend on his or her personality [introverts opting for smaller networks ] or on the size of the community he or she happens to be a member of (as seems to be the case here with the immigrant communities where opportunities for social A B C D interaction seem to be restricted to a small number of individuals by social exclusion). Note that all distributions ( Fig.,[1],Computer_Science,test,1.0,news,http://ct.moreover.com/?a=34615793773&p=1pl&v=1&x=B9OeehCkV4Axi__oIw0XTg 10.1126/science.aao4408,Computer_Science_easy_182,"""Our approach preserves the ability of policy-makers to set their own parameters and priorities,"" the researchers write.",Our algorithm is flexible and can accommodate multiple criteria and constraints.,"A simple change The researchers are not advocating for the algorithm to replace the decision-making of resettlement officials. ""Our approach preserves the ability of policy-makers to set their own parameters and priorities,"" the researchers write. ""For instance, in a computer-assisted assignment process, the algorithm might provide several recommendations, and placement officers could use their own discretion to determine the final assignment or override any suggestions.""","Our preferred case-level metric was the predicted probability that at least one refugee in the case would find employment at the location in question. Our algorithm is flexible and can accommodate multiple criteria and constraints. For the algorithm to obtain reliable predictions, it is important that the historical assignment process not be determined by unobserved refugee characteristics.",[1],Computer_Science,test,1.0,news,http://www.futurity.org/refugee-resettlement-algorithm-1658522-2/ 10.1073/pnas.1719233115,Computer_Science_easy_234,"But the bottom line here is that having more close relationships in your life should be possible at any time, but it's going to mean putting in the work, which will probably come at the expense of losing some less intimate relationships.","Since these technologies reduce the effective cost of maintaining some relationships, it should be easier for individuals to establish larger networks and this should promote the standard regime.","You could probably extrapolate this effect out to relationships within large or small companies for those of us whose social lives largely overlap with our careers. For example, people working in small startups might have a larger number of intense relationships than those in the wider corporate world. But the bottom line here is that having more close relationships in your life should be possible at any time, but it's going to mean putting in the work, which will probably come at the expense of losing some less intimate relationships.","More interestingly, perhaps, our model predicts how the increasing availability of online social networks may affect the way we handle our relationships. Since these technologies reduce the effective cost of maintaining some relationships, it should be easier for individuals to establish larger networks and this should promote the standard regime. However, if online relationships are cheaper to maintain because they obviate the costly business of physically meeting up with an alter , it follows that any increase in online network size will be associated with a reduction in average tie strength.",[1],Computer_Science,test,1.0,news,http://ct.moreover.com/?a=34615793773&p=1pl&v=1&x=B9OeehCkV4Axi__oIw0XTg 10.1145/2702123.2702397,Computer_Science_easy_247,"They plan to extend their mixed-reality game to different content areas to create a new educational system that bridges the advantages of physical and virtual worlds to improve children's science learning, understanding and enjoyment in a collaborative way.","The mixed-reality, mouse-control condition (#2) is significantly better (p<0.05), but the virtual, physicalcontrol condition (#3) is not.","They also determined that simple physical controls like shaking the tablet or pushing the earthquake button did little to improve either learning or enjoyment of the game. ""Mixed-reality games that support physical observation in the real world have a great potential to enhance learning and enjoyment for young children,"" the researchers say. They plan to extend their mixed-reality game to different content areas to create a new educational system that bridges the advantages of physical and virtual worlds to improve children's science learning, understanding and enjoyment in a collaborative way.","We can consider what choice improves learning most over a typical virtual, mouse-control game (#1 in Figure 10 ). The mixed-reality, mouse-control condition (#2) is significantly better (p<0.05), but the virtual, physicalcontrol condition (#3) is not. In other words, facilitating physical observation was more powerful than facilitating physical control through shaking the tablet.",[1],Computer_Science,test,1.0,news,http://www.theepochtimes.com/n3/1354229-why-tablets-cant-replace-real-world-schools/ 10.1126/science.aao4408,Computer_Science_easy_259,"""For instance, in a computer-assisted assignment process, the algorithm might provide several recommendations, and placement officers could use their own discretion to determine the final assignment or override any suggestions.""","Our approach led to gains of roughly 40 to 70%, on average, in refugees' employment outcomes relative to current assignment practices.","""Our approach preserves the ability of policy-makers to set their own parameters and priorities,"" the researchers write. ""For instance, in a computer-assisted assignment process, the algorithm might provide several recommendations, and placement officers could use their own discretion to determine the final assignment or override any suggestions."" Yet in contrast to more expensive policy interventions, such as job or language training for refugees, the results of the algorithm, the code of which is available for free to any organization or government, are promising, the researchers say.","Our approach led to gains of roughly 40 to 70%, on average, in refugees' employment outcomes relative to current assignment practices. This approach can provide governments with a practical and cost-efficient policy tool that can be immediately implemented within existing institutional structures. It is also one of the most consequential in maximizing refugees' economic integration and self-sufficiency as a first step toward a more comprehensive integration into society (7-9).",[1],Computer_Science,test,1.0,news,http://www.futurity.org/refugee-resettlement-algorithm-1658522-2/ 10.1126/science.aao4408,Computer_Science_easy_285,"The algorithm assigned placements for refugees that they project would increase their chances of finding employment by roughly 40 to 70 percent compared with how the refugees actually fared, according to the new study in Science.","On average, the employment rate was 34% under the actual assignment and 48% under the optimized assignment, which means that the optimized assignment would increase the employment rate above the baseline by roughly 41%.","In 2016 alone, about 65.6 million people were forced to flee their homes. The algorithm assigned placements for refugees that they project would increase their chances of finding employment by roughly 40 to 70 percent compared with how the refugees actually fared, according to the new study in Science. The group, from Stanford and ETH Zurich, says the algorithm, which could be implemented at virtually no cost, could help resource-constrained governments and resettlement agencies find the best places for refugees to relocate.","In addition, the algorithmic assignment yielded higher employment rates in almost every location, including locations that had higher and lower baseline employment rates. On average, the employment rate was 34% under the actual assignment and 48% under the optimized assignment, which means that the optimized assignment would increase the employment rate above the baseline by roughly 41%. Our algorithmic assignment considerably increased expected refugee employment over the status quo assignment (Fig.",[1],Computer_Science,test,1.0,news,http://www.futurity.org/refugee-resettlement-algorithm-1658522-2/ 10.1073/pnas.1719233115,Computer_Science_easy_294,"For example, people working in small startups might have a larger number of intense relationships than those in the wider corporate world.","where = ( 1, 2, .","You could probably extrapolate this effect out to relationships within large or small companies for those of us whose social lives largely overlap with our careers. For example, people working in small startups might have a larger number of intense relationships than those in the wider corporate world. But the bottom line here is that having more close relationships in your life should be possible at any time, but it's going to mean putting in the work, which will probably come at the expense of losing some less intimate relationships.","We provide evidence of the existence of both regimes in real communities and analyze the consequences of these findings in our understanding of social groups. where = ( 1, 2, . Urns are initially all alike, so without loss of generality we can sort them by decreasing costs, s1 > s2 > · · · > sr .",[1],Computer_Science,test,1.0,news,http://ct.moreover.com/?a=34615793773&p=1pl&v=1&x=B9OeehCkV4Axi__oIw0XTg 10.1073/pnas.1719233115,Computer_Science_easy_349,"""If one has a large number of relationships, it must mean that they are almost all superficial.""","Therefore, a second, as yet unnoticed, regime is predicted in which the structure is reversed-the more demanding the layers, the more populated they are.","""It is impossible to have relationships with 150 people and for them all to be intimate,"" explains co-author Ignacio Tamarit. ""If one has a large number of relationships, it must mean that they are almost all superficial."" The researchers predicted this effect using a mathematical theory and then found that it held true in actual data gathered on the personal networks of isolated immigrant communities in Spain.","However, in the inverse regime (µ < 0) χ k quickly approaches 1 as k increases, implying that most links are within the innermost circle. Therefore, a second, as yet unnoticed, regime is predicted in which the structure is reversed-the more demanding the layers, the more populated they are. This regime is expected to arise when the ratio S /L is particularly large.",[1],Computer_Science,test,1.0,news,http://ct.moreover.com/?a=34615793773&p=1pl&v=1&x=B9OeehCkV4Axi__oIw0XTg 10.1073/pnas.1719233115,Computer_Science_easy_361,The theory also works in reverse.,The data from the community of students can be found at dx.doi.org/10.1371/journal.pone.0151588.,"So having, say, eight very close friends instead of four probably means you have less time for second or third-tier friends. The theory also works in reverse. Perhaps 150 friends seems like a ridiculously small number of people.","Try to use pseudonyms, but be sure you can recognize them later."" The data from the community of students can be found at dx.doi.org/10.1371/journal.pone.0151588. The model presents singularities when all of the relationships happen to be in either the first layer [then f(µ) = 0, which holds for µ → −∞] or the last layer [then f(µ) = 1, which holds for µ → +∞].",[1],Computer_Science,test,1.0,news,http://ct.moreover.com/?a=34615793773&p=1pl&v=1&x=B9OeehCkV4Axi__oIw0XTg 10.1073/pnas.1719233115,Computer_Science_easy_363,Perhaps 150 friends seems like a ridiculously small number of people.,"Finally, from a socio-centric perspective, our model suggests a way to identify whether an interconnected set of individuals (i.e., a community in the technical network analysis sense) is ""small"" or not, namely according to the regime of their ego networks.",The theory also works in reverse. Perhaps 150 friends seems like a ridiculously small number of people. Odds are that all that digital friending came at the expense of more intimate relationships.,"This would incentivize weak relationships, which might well be another reason why the inverse regime has remained largely unnoticed until now. Finally, from a socio-centric perspective, our model suggests a way to identify whether an interconnected set of individuals (i.e., a community in the technical network analysis sense) is ""small"" or not, namely according to the regime of their ego networks. In such a setting we find that the change of regime happens at a network size of 88 and that there is a maximum network size of 220 [a value close to the maximum observed network size of ∼250 ].",[1],Computer_Science,test,1.0,news,http://ct.moreover.com/?a=34615793773&p=1pl&v=1&x=B9OeehCkV4Axi__oIw0XTg 10.1145/2702123.2702397,Computer_Science_easy_384,A game that combined real-world experiments with interactions on a computer tablet improved learning by almost five times more than screen-only alternatives.,"Why do you think this tower fell first?""","A game that combined real-world experiments with interactions on a computer tablet improved learning by almost five times more than screen-only alternatives. The final analysis shows that the mixed-reality game improved learning by almost five times more than the screen-only alternatives, both in the mouse-controlled and physically controlled conditions. Not only that, but students enjoyed the game more in the mixed-reality conditions.","Why do you think this tower fell first?"" Why do you think this tower fell first?"" This scenario is repeated for different contrasting cases targeting height, wide base, symmetry and center of mass principles ( Figure 3) .",[1],Computer_Science,test,1.0,news,http://www.theepochtimes.com/n3/1354229-why-tablets-cant-replace-real-world-schools/ 10.1126/sciadv.1601114,Computer_Science_easy_403,"The computational modeling revealed that the input pattern closest to the stored pattern exhibits the fastest convergence time to the stable synchronization behavior, and is the most effective at recognizing patterns.",The results of the modeling show that the input pattern closest to the stored pattern exhibits the fastest convergence time to stable synchronization behavior.,"""For the first time, we have been able to show how these materials would perform the computations for pattern recognition."" The computational modeling revealed that the input pattern closest to the stored pattern exhibits the fastest convergence time to the stable synchronization behavior, and is the most effective at recognizing patterns. However, Dr. Yashin notes that the results are similar to nature, which moves at a ""snail's pace.""","We show that the network of coupled, synchronizing BZ-PZ oscillators can perform pattern recognition. The results of the modeling show that the input pattern closest to the stored pattern exhibits the fastest convergence time to stable synchronization behavior. In this way, networks of coupled BZ-PZ oscillators achieve pattern recognition.",[5],Computer_Science,test,5.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/W3wVoi1u1zA/ 10.1038/s41598-018-36809-y,Computer_Science_easy_446,"Ms. Cathey, who plans to attend medical school after taking a gap year, said doing research gave her a more comprehensive understanding of the engineering principles she was studying.",6e ).,"""The best part about my experience was teaching myself new skills and applying them to improve an important research method,"" he said. Ms. Cathey, who plans to attend medical school after taking a gap year, said doing research gave her a more comprehensive understanding of the engineering principles she was studying. ""This project been a good learning experience to see what kind of commitment it takes to make an meaningful contribution to the field,"" she said.","The close proximity to the heart and secure placement of the electrodes results in a higher quality signal with less noise and an approximately 35% increase in amplitude. 6e ). This approach also allows easy customization and rapid, inexpensive prototyping, providing both optical mappers and other investigators an alternative that mitigates the overall cost of optical mapping systems and catalyzes new study protocol development.",[1],Computer_Science,test,1.0,news,http://ct.moreover.com/?a=38768191657&p=1pl&v=1&x=vuF8xNUDu8imX8EinJ4Sow 10.1073/pnas.1219068110,Computer_Science_easy_458,"Regardless, the newly discovered crane fly fossils are noteworthy for their incredible detail alone.",S3C and S4 ).,"""This is important because trilobites are some of the earliest organisms known with complex eyes, and their function is immensely important when assessing the evolution of compound eyes."" Regardless, the newly discovered crane fly fossils are noteworthy for their incredible detail alone. It's rare enough to find bone fossils, let alone be able to look into the eyes of an insect that lived and died so long ago.","To avoid spatial aliasing or blind spots in the visual field, the acceptance angle Δρ of each ommatidium must closely approach the interommatidial angle Δφ (1, 24) (Fig. S3C and S4 ). 3 A and D shows representative examples of ASFs measured along a single row and a single column, respectively.",[1],Computer_Science,test,1.0,news,http://ct.moreover.com/?a=39947725636&p=1pl&v=1&x=AehSyvOrKImgsSb4gQbSnA 10.1287/isre.1100.0339,Computer_Science_easy_462,Thatas because they overestimated their motivation to work out.,"If the process of information transmission does not depend on user tastes or homophily, we should observe that the impact of the originating channel's position in the friend network and subscriber networks should be similar throughout the diffusion process.",Thatas because they overestimated their motivation to work out. Hyperbolic discounting is just one challenge of operating in a creative industry. Itas equally challenging to decide the timing.,"Within-group friends' influence is greater friend networks, creating a social multiplier effect that magnifies the impact of user tastes through social preferences such as conformity. If the process of information transmission does not depend on user tastes or homophily, we should observe that the impact of the originating channel's position in the friend network and subscriber networks should be similar throughout the diffusion process. We also find that the impact of nonlocal ties is stronger in the process of diffusion than that of within-group ties.",[1],Computer_Science,test,1.0,news,http://ct.moreover.com/?a=38408878498&p=1pl&v=1&x=M50upELvsk8xhx-O0-2ZYA 10.1145/3243734.3243846,Computer_Science_easy_470,"As Basin's team determined, data protection will be improved significantly with the new protocol in comparison with 3G and 4G technologies.","5.2.5,6.12].","""It is therefore possible for a poor implementation of the current standard to result in users being charged for the mobile phone usage of a third party."" As Basin's team determined, data protection will be improved significantly with the new protocol in comparison with 3G and 4G technologies. In addition, 3GPP succeeded in closing a gap with the new standard that had previously been exploited by IMSI catchers.","In 5G, the SUPI is considered sensitive and must remain secret since it uniquely identifies users [TS 33.501, Sec. 5.2.5,6.12]. Indeed, an attacker who obtains this value can identify a subscriber, leading to classical user location attacks (see [TS 133 .102, Sec.",[1],Computer_Science,test,1.0,news,http://ct.moreover.com/?a=37349386607&p=1pl&v=1&x=c2Aua66v-t5SCZShWqKiXg 10.1016/j.compedu.2017.08.007,Computer_Science_easy_473,"(Finland, of course, is ahead of the curve on this front, having jettisoned the idea of teaching by subjects in favor of showing students to make connections between math, history, economics, and language under umbrella topics like ""The European Union."")",Z=1.49) .,"First, there's interdisciplinary academic intelligence, the ability to tie subjects together rather than studying them in silos. (Finland, of course, is ahead of the curve on this front, having jettisoned the idea of teaching by subjects in favor of showing students to make connections between math, history, economics, and language under umbrella topics like ""The European Union."") This is something humans can excel at; robots, not so much.","K= 0.55, HSch. Z=1.49) . The low IV values can be achieved if students continue their level of physical interactivity for longer periods of times, rather than having frequent changes in their interactivity.",[1],Computer_Science,test,1.0,news,http://ct.moreover.com/?a=34624602793&p=1pl&v=1&x=kCuYBFj1SKvsfceSHywniw 10.1126/scirobotics.aau0275,Computer_Science_easy_495,"You could be forgiven for thinking that the toughest, most durable robot would be some sort of ultra-hard, metal alloy skeleton like the Terminator, but sometimes soft and flexible is the way to go.","Furthermore, in addition to load bearing and crash resilience, the compliant origami also stored elastic energy that can be leveraged for self-deployment of the drone from a folded configuration.","You could be forgiven for thinking that the toughest, most durable robot would be some sort of ultra-hard, metal alloy skeleton like the Terminator, but sometimes soft and flexible is the way to go. But, the researchers tell Inverse, with one key difference: The design, a new composite thatas flexible enough to absorb damage, but rigid enough to remain aerodynamic, and was inspired by the material properties of insect wings. aWhat theyave done with regard to tailoring the athreshold forcea a the threshold at which the switch from rigid to soft occurs a I think thatas pretty key for structures that need to withstand impacts.a At the core of the Swiss groupas innovation is a stretched-out elastic layer, sort of like a rubber band that desperately wants to return back to form.","The origami structure described here achieved similar performance with a scalable, rapid, and cost-effective manufacturing process. Furthermore, in addition to load bearing and crash resilience, the compliant origami also stored elastic energy that can be leveraged for self-deployment of the drone from a folded configuration. When the arms buckle due to a horizontal flexural load, the apex angle collapsed, and the arm can be wrapped around the main frame by folding along the transversal folds (Fig.",[1],Computer_Science,test,1.0,news,http://ct.moreover.com/?a=34656802818&p=1pl&v=1&x=q1dI-Su0Ci1nNp4RIJY6xg 10.1126/scirobotics.aat5643,Computer_Science_easy_504,Look around and you'll likely see something that runs on an electric motor.,This results in a quadratic increase in force density as dimensions are reduced.,"Look around and you'll likely see something that runs on an electric motor. But these qualities change for the worse when such motors are shrunk down to sizes smaller than a cubic centimeter. The actuators move with a level of precision, efficiency, and power that has not yet been possible at the microscale.","Scaling to smaller dimensions: Force, power, and efficiency Increasing the power density of microhydraulic actuators is straightforward: Decreasing droplet pitch and height reduces the droplet mass per width quadratically, whereas force per droplet width stays constant, at approximately the surface tension. This results in a quadratic increase in force density as dimensions are reduced. The actuation velocity stays roughly constant, because the increased force is counterbalanced by increased viscous losses.",[1],Computer_Science,test,1.0,news,http://news.mit.edu/2018/using-electricity-and-water-new-motor-can-slide-microrobots-into-motion-1119 10.1073/pnas.1802103115,Computer_Science_easy_517,"It is an important step toward general artificial intelligence systems -- computers that learn on their own, are intuitive, make decisions based on reasoning and interact with humans in a more human-like way.","Such templates, however, do not constitute detailed object prototypes of the kind illustrated in Fig.","It is an important step toward general artificial intelligence systems -- computers that learn on their own, are intuitive, make decisions based on reasoning and interact with humans in a more human-like way. Computers, of course, also cannot explain their rationale for determining what the object in a photo represents: AI-based systems do not build an internal picture or a common-sense model of learned objects the way humans do. ""That contextual learning is a key feature of our brains, and it helps us build robust models of objects that are part of an integrated worldview where everything is functionally connected.""","Note that the ingenious Poselets approach is based on processing manually tagged data to generate hundreds of distinctive templates (and associated classifiers obtained through extensive supervised training) that have exemplars with various views/poses and scales embedded in them. Such templates, however, do not constitute detailed object prototypes of the kind illustrated in Fig. 1 .The slightly lower recall rate in our model is to be expected as the weak kNN classifer misses many of the viewlets that are otherwise present in an image.",[1],Computer_Science,test,1.0,news,http://ct.moreover.com/?a=38047476615&p=1pl&v=1&x=1Og_Fr_sTcGeYgIUL-JQFQ 10.1126/scirobotics.aat0430,Computer_Science_easy_522,"Such a mission would require that the robots be able to determine, on their own, which tasks to perform and in what order to perform them; for instance, there is no use attempting to pull a victim out of rubble if the rubble has not yet been cleared.",The results show that the two assumptions of Mark I can be overcome (Figs.,"Such a mission would require that the robots be able to determine, on their own, which tasks to perform and in what order to perform them; for instance, there is no use attempting to pull a victim out of rubble if the rubble has not yet been cleared. The results of their research are published in Science Robotics this Wednesday, July 18. This study demonstrates, for the first time, that robots are able to collectively determine a sequence of actions whose required order was previously unknown.","The exploration of the permutation tree is distributed. The results show that the two assumptions of Mark I can be overcome (Figs. 4, D and E, and 7): The task sequencing problem can be solved even if no immediate feedback is received by the robots, and the tasks are more than three.",[1],Computer_Science,test,1.0,news,http://ct.moreover.com/?a=34582615850&p=1pl&v=1&x=FeeMrtBFz8BSWvLbS6ubMQ 10.1016/j.trc.2018.02.005,Computer_Science_easy_526,That's cheaper than downtown parking - and often more efficient than driving a few miles to park in a cheaper area.,"The second wave is also damped by the control law, but its presence for a period of the active control accounts for the difference relative to the period where no waves occurred in the uncontrolled period at the start of the experiment.","Creating a traffic jam and moving very slowly in it would cost at little as $0.29 an hour in San Francisco, Millard-Ball's model showed; moving at 8.7 miles per hour, the average for the evening rush hour in that city in 2017, would imply a cost of $1.98 per hour. That's cheaper than downtown parking - and often more efficient than driving a few miles to park in a cheaper area. Millard-Ball calculated that cruising while waiting for the owner-passenger would be the most cost-effective option for 40 percent of trips to downtown San Francisco.","By examining the trajectories ( Figure 5 ), it is apparent that the control law is able to eliminate the initially present wave, but another wave is generated during the control period. The second wave is also damped by the control law, but its presence for a period of the active control accounts for the difference relative to the period where no waves occurred in the uncontrolled period at the start of the experiment. To conclude, these experiments demonstrate that traffic flow control via low penetration rate automated vehicles is in fact possible.",[1],Computer_Science,test,1.0,news,http://ct.moreover.com/?a=38474455319&p=1pl&v=1&x=IqN4qjKRoK_oUuABIl0bAg 10.1093/bioinformatics/btu831,Computer_Science_easy_530,"It can remain inside the body, reproducing, for decades.",The non-linear SVM is used in QDREC as the default classifier because it exhibited less parameter sensitivity and more reliable convergence than the linear SVM.,"The software is now available for parasitologists, biologists and other drug developers around the world to use -- free of charge -- in the quest to find a cure for schistosomiasis. It can remain inside the body, reproducing, for decades. While a drug, called praziquantel, does exist to treat the disease, Singh pointed out, using a single drug to treat millions of people across a large area over decades carries a high risk of the parasite building resistance.","Classification accuracy and the mean and standard deviation of NRMSE, correlation and log 10 (P-value) are shown for 12 drugs (atorvastatin, fluvastatin, lovastatin, pravastatin, rosuvastatin, simvastatin, closantel, ibandronate, K11777, niclosamide, praziquantel and sorafenib). The non-linear SVM is used in QDREC as the default classifier because it exhibited less parameter sensitivity and more reliable convergence than the linear SVM. All results are for two-stage classification using parasite and control feature vector tuples.",[1],Computer_Science,test,1.0,news,http://www.sciencedaily.com/releases/2015/01/150113111623.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29 10.1093/nar/gkw1133,Computer_Science_easy_533,"""There's going to need to be some cultural reckoning with some of the earned mistrust that's happened in the biomedical establishment and in law enforcement,"" she said.","The full GWAS Catalog is also available in OWL/RDF format, allowing users to install their own triple store and run their own version of the diagram generation software as well as query the GWAS Catalog in SPARQL or another graph querying language.","Creating diverse genetic datasets will require a large systemic change, said Martin. ""There's going to need to be some cultural reckoning with some of the earned mistrust that's happened in the biomedical establishment and in law enforcement,"" she said. ""These are not easy issues to change, but in general we need much more diverse representation to have equitable use of this type of genetic technology.""","The redevelopment of the diagram generation software using a Virtuoso triplestore to represent the underlying data, has led to more than 1000-fold improvement in diagram generation time, and diagram and data releases are now synchronized weekly. The full GWAS Catalog is also available in OWL/RDF format, allowing users to install their own triple store and run their own version of the diagram generation software as well as query the GWAS Catalog in SPARQL or another graph querying language. The GWAS Catalog is committed to providing support for users.",[1],Computer_Science,test,1.0,news,http://ct.moreover.com/?a=38873442105&p=1pl&v=1&x=PVR3ZGMVz9x4ZkuHA7OYWw 10.1016/j.neuroimage.2015.09.008,Computer_Science_easy_535,"aEURoeVascular compliance is a useful marker for a number of cardiovascular diseases, such as hypertension and diabetes,aEUR Wang said.",5.,"That team found that the stiffer the arteries were, the smaller the change in the arterial blood volume between the two cardiac phases, because stiff arteries are not as able to change shape or comply with the blood pressure changes as elastic arteries are, said study senior author Danny J.J. Wang, an associate professor of neurology and a researcher in the Ahmanson-Lovelace Brain Mapping Center at UCLA. aEURoeVascular compliance is a useful marker for a number of cardiovascular diseases, such as hypertension and diabetes,aEUR Wang said. The UCLA team compared stiffness measurements in young and elderly patients, and found that arterial stiffness is significantly increased in elderly patients.","A reduction of VC with age (r = − 0.52, p = 0.026) was observed, which is consistent with the finding shown in Fig. 5. 6b shows the scatter plot between global CBF measured by 3D GRASE pCASL and age across subjects, which indicates a significant trend of decreasing gray matter (GM) CBF with aging (r = −0.49, p = 0.041).",[1],Computer_Science,test,1.0,news,http://healthmedicinet.com/news/researchers-discover-method-to-measure-stiffness-of-arteries-in-the-brain/ 10.1098/rsif.2014.0623,Computer_Science_easy_544,Bitcoms do not belong to anyone.,"The VAR reveals the following feedback cycles: -'social' cycle: search volume increases with price (f P,S ¼ 0.386), word of mouth increases with search volume (f S,W ¼ 0.243), and price increases with word of mouth (f W,P ¼ 0.1).","""The big question is how such a high-performance system could be used for collaborative activities which go beyond the production of money"", comments Perony. Bitcoms do not belong to anyone. This study already outlines today the tools for accurately quantifying and analyzing the social dynamics of collaborative systems of this kind in the future.","In this statistical model, the change in each variable on a given day fDU t , DP t , DS t , DW t g is a linear combination of the changes in all variables fDU t21 , DP t21 , DS t21 , DW t21 g on the previous day, including a deterministic, a periodic and an error term . The VAR reveals the following feedback cycles: -'social' cycle: search volume increases with price (f P,S ¼ 0.386), word of mouth increases with search volume (f S,W ¼ 0.243), and price increases with word of mouth (f W,P ¼ 0.1). Simultaneously accounting for all dependencies between the four variables emphasizes the influence of word of mouth on price, revealing a stronger relation than cannot be observed with pairwise correlation analysis (more details in the electronic supplementary material, §S3).",[1],Computer_Science,test,1.0,news,http://www.redorbit.com/news/technology/1113209564/economy-of-bitcoins-study-081014/ 10.1287/mnsc.2014.2115,Computer_Science_easy_548,"Robinson also recommends taking brief respites from your day to meditate, go for a walk or go outside for lunch - ""don't be a desk potato,"" he says.","We find that more than 120,000 deaths per year and approximately 5-8% of annual healthcare costs are associated with and may be attributable to how U.S. companies manage their work force.","Be honest, particularly if your health is suffering as a result of workplace stress. By eliminating roadblocks within you, such as pessimism or a tendency to complain frequently about your problems, Robinson says you can better manage the pressure and not let your stress affect those around you. Robinson also recommends taking brief respites from your day to meditate, go for a walk or go outside for lunch - ""don't be a desk potato,"" he says.","Specifically, the model separately derives optimistic and conservative estimates of the effect of multiple workplace exposures on health, and uses optimization to calculate upper and lower bounds around each estimate, which accounts for the correlation between exposures. We find that more than 120,000 deaths per year and approximately 5-8% of annual healthcare costs are associated with and may be attributable to how U.S. companies manage their work force. Our results suggest that more attention should be paid to management practices as important contributors to health outcomes and costs in the U.S..",[1],Computer_Science,test,1.0,news,http://health.usnews.com/health-news/health-wellness/articles/2015/06/15/how-job-stress-might-be-killing-you-and-what-you-can-do-about-it 10.1016/j.future.2019.04.025,Computer_Science_easy_560,"However, in the future it's likely that image databases used for facial recognition will need to include partial images as well, so that the models can be trained correctly to recognise a face even when not all of it is visible.""",Outcomes of their experiments on four face databases demonstrated that their approach outperformed other state of the art methods at the time.,"This opens up greater possibilities for the use of the technology for security or crime prevention. ""Our experiments now need validating on a much larger dataset. However, in the future it's likely that image databases used for facial recognition will need to include partial images as well, so that the models can be trained correctly to recognise a face even when not all of it is visible.""","The TPGM method minimises a geometric and textural cost function. Outcomes of their experiments on four face databases demonstrated that their approach outperformed other state of the art methods at the time. Similarly, Cai et al.",[1],Computer_Science,test,1.0,news,http://ct.moreover.com/?a=39121294135&p=1pl&v=1&x=yGqe51nf6jBzSd9VB_eZaQ 10.1038/srep04001,Computer_Science_easy_586,So it'll be fascinating to see what other insights emerge from this kind of work.,"In the long run the system always reaches an equilibrium state where all spreaders have turned into stiflers, ∂ t i(t) = 0, and ∂ t r(t) = 0.","What's interesting about this result is that it only emerges when the time-varying nature of the network becomes visible. ""The presented results underline the subtleties inherent to the analysis of dynamical processes in time-varying networks,"" say Karsai and co. So it'll be fascinating to see what other insights emerge from this kind of work.","We assume that only their ratio matters for the spreading behaviour (supporting results are summarized in SM). In the long run the system always reaches an equilibrium state where all spreaders have turned into stiflers, ∂ t i(t) = 0, and ∂ t r(t) = 0. Different parameters provide different penetration of the rumor in the network.",[1],Computer_Science,test,1.0,news,http://www.technologyreview.com/view/512951/how-strong-social-ties-hinder-the-spread-of-rumours?nopaging=1 10.1177/2472555218773034,Computer_Science_easy_587,These principles are illustrated in the review and supported with recent examples of discovery projects against a range of potential antibiotic targets.,"In general, no particular technique can be regarded as a ""bestin-class"" solution, but it is useful to be aware of and consider all available options.","These principles are illustrated in the review and supported with recent examples of discovery projects against a range of potential antibiotic targets. Because the fragments are small, they are more likely to fit into a binding site and each fragment represents a huge number of potential compounds.","It also has high requirements for the solubility of the ligand (if titrated). In general, no particular technique can be regarded as a ""bestin-class"" solution, but it is useful to be aware of and consider all available options. Each of the techniques also has particular requirements in terms of the solubility of the protein and the solubility of the ligands screened and can robustly detect different dynamic ranges of binding affinity.",[1],Computer_Science,test,1.0,news,http://ct.moreover.com/?a=34362348449&p=1pl&v=1&x=xoYk4uWPkuPY2Dupfsnvvg 10.1140/epjds/s13688-018-0166-4,Computer_Science_easy_595,The same wasn't true for so-so thinking from major universities.,"When a set of curves are parameterized special cases of a more general function, the generic function can be identified and estimated by ""rescaling"" the individual curves so that they collapse onto each other .","When mid-level ideas began at less prestigious schools, they tended to stall, not reaching the full network. The same wasn't true for so-so thinking from major universities. ""If you start a medium- or low-quality idea at a prestigious university, it goes much farther in the network and can infect more nodes than an idea starting at a less prestigious university,"" Morgan said.","This analysis reveals that ideas originating from the lowest-prestige universities, even if they are of the highest quality, are unlikely to spread to the whole network (red line, Figure 8A ), and again reinforces the substantial structural advantage afforded to more prestigious universities. When a set of curves are parameterized special cases of a more general function, the generic function can be identified and estimated by ""rescaling"" the individual curves so that they collapse onto each other . This ansatz converts p and d into an ""effective"" transmission probability p * , and its form illustrates the exponential rescaling effect of prestige (via the decile variable d now) on the raw transmission probability p. Hence, as the prestige of the originating university decreases, in order to produce an epidemic of equivalent size, the transmission probability of the idea must increase at an exponential rate to compensate.",[1],Computer_Science,test,1.0,news,http://ct.moreover.com/?a=37611989007&p=1pl&v=1&x=-BRiMLnRXWRXnDrJvOHI2Q 10.1186/s13287-015-0250-7,Medicine_100,Tissues from equine cadaver ligaments up to 72 hours of post-mortem: a promising reservoir of stem cells.,"The present work is the first, in both animal and human, to show that tissues harvested from cadaveric ligaments up to 72 hours postmortem represent an available reservoir of specific stem cell populations.","Tissues from equine cadaver ligaments up to 72 hours of post-mortem: a promising reservoir of stem cells. Phase contrast microscopy revealed that cells with fibroblast-like appearance were predominant in the culture. Differentiation assays proved that EC-MSCs are able to differentiate towards mesodermal lineages (osteogenic, adipogenic, chondrogenic).","Taking these observations into account, fundamental and clinical research studies are now required to investigate whether MSCs isolated from equine cadavers are suitable, abundant, and readily available to be used in future clinical applications. The present work is the first, in both animal and human, to show that tissues harvested from cadaveric ligaments up to 72 hours postmortem represent an available reservoir of specific stem cell populations. SLs were confirmed free of any damage following examination of the tissues both macroscopically and microscopically.","[5.0, 5.0, 5.0, 5.0, 5.0]",Medicine,test,5.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/6X1w7O2uQ6Y/ 10.1083/jcb.201804028,Medicine_113,"And thanks to their newly-developed in vitro approach, in future it will be possible to identify other proteins that operate in the fusion process.","Thus, Nyv1 is dispensable for bulk autophagy function.","These results help to understand autophagy and its underlying molecular processes better. And thanks to their newly-developed in vitro approach, in future it will be possible to identify other proteins that operate in the fusion process. Note: material may have been edited for length and content.","Both nyv1Δ and WT cells displayed Pho8Δ60 activity ( Fig. Thus, Nyv1 is dispensable for bulk autophagy function. Furthermore, Ykt6 and Sec22 act together with the SNA RE proteins Sso1 and Sec9 in Atg9 trafficking during early steps of autophagy .","[1.0, 2.0, 1.0, 3.0, 2.0]",Medicine,test,1.8,news,http://ct.moreover.com/?a=34819790734&p=1pl&v=1&x=8aQKBEotEoZ2dQYDB6dLKA 10.1093/gerona/glv133,Medicine_119,"Understanding frailty could potentially help us extend people's quality of life into their later years.""","In conclusion, our findings support the importance of frailty in late-life health etiology.","""We would love for frailty assessment to become a standard component of assessment of older Americans. Understanding frailty could potentially help us extend people's quality of life into their later years."" Understanding frailty, and finding ways to prevent its onset or slow its progression, could improve older people's quality of life by extending their so-called robust years.","These data confirm that rapid decline is not inevitable after the mid-80s. In conclusion, our findings support the importance of frailty in late-life health etiology. They bolster evidence for deploying frailty measures as clinical tools to identify at-risk older adults in whom interventions might be targeted.","[1.0, 5.0, 5.0, 4.0]",Medicine,test,4.0,news,http://www.futurity.org/frailty-demographics-1012392/ 10.1073/pnas.1407787111,Medicine_122,"""It is particularly noteworthy that the networks we found to have lagging maturation in ADHD are linked to the very behaviors that are the symptoms of ADHD,"" he says.",Our results invite further investigation into the neurobiological mechanisms in ADHD that produce delays in development of large-scale networks.,"These networks, and the connections between them, mature throughout early childhood all the way to young adulthood. ""It is particularly noteworthy that the networks we found to have lagging maturation in ADHD are linked to the very behaviors that are the symptoms of ADHD,"" he says. ""The results of this study set the stage for the next phase of this research, which is to examine individual components of the networks that have the maturational lag,"" he says.",Our results provide strong initial evidence that these alterations arise from delays in typical maturational patterns. Our results invite further investigation into the neurobiological mechanisms in ADHD that produce delays in development of large-scale networks. We found significant and specific maturational lag in connections within default mode network (DMN) and in DMN interconnections with two task positive networks (TPNs): frontoparietal network and ventral attention network.,"[5.0, 5.0, 3.0, 3.0]",Medicine,test,4.0,news,http://www.sciencedaily.com/releases/2014/09/140915153607.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29 10.1098/rspb.2014.2335,Medicine_140,"The researchers were surprised to discover that during the winter, when the bats are hibernating, the fungus can infect nearly every bat in a colony.","The seasonal patterns of prevalence and loads of P. destructans were remarkably consistent for all six bat species, with a sharp increase in prevalence between autumn and early winter when bats began to hibernate and a peak in fungal load in late winter at the end of hibernation.","The researchers were surprised to discover that during the winter, when the bats are hibernating, the fungus can infect nearly every bat in a colony. Bats that survive the winter are able to clear the infection during summer when their body temperatures are above the growth limit of the fungus. But the remarkably high rate of infection during hibernation leads to high mortality rates at the time of year when bat populations are naturally at their lowest, before the females give birth in the summer.","Decreases in loads and prevalence over the summer did not parallel changes in colony size for M. lucifugus, which broadly overlapped and The seasonal patterns of prevalence and loads of P. destructans were remarkably consistent for all six bat species, with a sharp increase in prevalence between autumn and early winter when bats began to hibernate and a peak in fungal load in late winter at the end of hibernation. In contrast to many other systems , we found no support for the hypothesis that birth pulses drive seasonality.","[2.0, 5.0, 4.0, 3.0]",Medicine,test,3.5,news,http://www.sciencedaily.com/releases/2014/12/141203084101.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29 10.1210/en.2013-1955,Medicine_145,"If you're drinking from a water bottle or eating from a plastic container, chances are you're consuming it right now.","As previously observed (28), progressive malignancy incidence was noted over time with highest HG-PIN and cancer incidence present at 4 months.","""Our research provides the first direct evidence that exposure to BPA during development, at the levels we see in our day-to-day lives, increases the risk for prostate cancer in human prostate tissue,"" Gail Prins, a professor of physiology and lead author of the paper, said in a press release. If you're drinking from a water bottle or eating from a plastic container, chances are you're consuming it right now. According to the study authors, avoiding the chemical altogether is a next-to impossible feat.","Together, these results document that levels of bioactive BPA in the present study are similar to levels found in human umbilical cord blood and newborns in the general population . As previously observed (28), progressive malignancy incidence was noted over time with highest HG-PIN and cancer incidence present at 4 months. Examples of HG-PIN and prostate adenocarcinoma as well as benign lesions of hyperplasia and SQM are shown in Fig 5 with PSA immunostaining to confirm their human origin and lack of basal cell staining to confirm carcinoma.","[1.0, 1.0, 1.0]",Medicine,test,1.0,news,http://www.medicaldaily.com/bpa-exposure-utero-may-triple-risk-prostate-cancer-can-we-do-anything-about-it-266535 10.1210/en.2013-1955,Medicine_176,"""We believe that BPA actually reprograms the stem cells to be more sensitive to estrogen throughout life, leading to a life-long increased susceptibility to diseases including cancer,"" Prins said.","Similar to the prostasphere assay, 1-10 nM E 2, but not 100 nM, significantly increased the percentage of stem-like cells in primary cultures indicating a stimulation of their self-renewal capacity (Fig 1C) .","""The findings of adverse effects of BPA in human tissue are highly relevant and should encourage agencies like the Food & Drug Administration to re-evaluate their policies in the near future."" The amount of BPA given to the mice was equal to the levels an average person ingests. ""We believe that BPA actually reprograms the stem cells to be more sensitive to estrogen throughout life, leading to a life-long increased susceptibility to diseases including cancer,"" Prins said.","As shown in Fig 1A, (Fig 1B) . Similar to the prostasphere assay, 1-10 nM E 2, but not 100 nM, significantly increased the percentage of stem-like cells in primary cultures indicating a stimulation of their self-renewal capacity (Fig 1C) . Collectively, these findings show that estrogen stimulates human prostate epithelial stem cell self-renewal and progenitor cell amplification (prostasphere size), with greatest effects observed at lower E 2 doses.","[1.0, 1.0, 2.0, 2.0]",Medicine,test,1.5,news,http://www.scienceworldreport.com/articles/12081/20140110/fetal-exposure-to-chemicals-in-plastic-bottles-increases-risk-of-prostate-cancer-later-study-confirms.htm 10.1136/annrheumdis-2013-203804,Medicine_178,"Related Study reveals distinct forms of foot osteoarthritis The burden associated with midfoot OA was reflected in affected individuals' frequent use of health care resources: During the past year, 46% of them had consulted their primary care physicians about their foot pain, 48% had been to a podiatrist, and 19% had seen a physical therapist (Arthritis Res Ther.","In addition, after excluding inflammatory arthritis, 129 clinic attenders had disabling foot pain but did not meet criteria for radiographic foot OA.","Midfoot OA was most prevalent in women older than 75 years; however, contrary to the conventional wisdom, a history of frequently wearing high-heeled shoes posed no increased risk. Related Study reveals distinct forms of foot osteoarthritis The burden associated with midfoot OA was reflected in affected individuals' frequent use of health care resources: During the past year, 46% of them had consulted their primary care physicians about their foot pain, 48% had been to a podiatrist, and 19% had seen a physical therapist (Arthritis Res Ther. ""We found that OA affected both feet significantly more than was expected by chance, and we identified strong symmetrical patterns.","Again, the 1st MTPJ was most commonly affected (n=58), followed by the 2nd CMJ (n=52), TNJ (n=41), NCJ (n=24) and 1st CMJ (n=15). In addition, after excluding inflammatory arthritis, 129 clinic attenders had disabling foot pain but did not meet criteria for radiographic foot OA. Seventy-eight (60%) of these had grade 1 osteophyte or joint space narrowing in one or more joints in either foot.","[1.0, 4.0, 3.0, 2.0]",Medicine,test,2.5,news,http://ct.moreover.com/?a=39498153871&p=1pl&v=1&x=ABngbXsk5KufxyHrE-m2mg 10.1002/cncr.28769,Medicine_187,"""Prostate cancer has an excellent prognosis.","This idea is supported by the existence of a strong temporal effect on kidney cancer risk, with a sharp increase in risk restricted to the year immediately after the initial prostate cancer diagnosis (see online Supporting Information).","Radiation therapy is a standard treatment for prostate cancer and the researchers stress that their findings should not prohibit anyone from choosing this treatment, in particular men who are not good candidates for surgery. ""Prostate cancer has an excellent prognosis. ""Long-term survivors who have undergone treatment with radiation and their physicians should be careful to monitor for symptoms of bladder and rectal cancer.""","Conversely, the increased risk of certain cancers may be explained by enhanced surveillance and screening after a prostate cancer diagnosis, leading to detection of latent malignancies. This idea is supported by the existence of a strong temporal effect on kidney cancer risk, with a sharp increase in risk restricted to the year immediately after the initial prostate cancer diagnosis (see online Supporting Information). Our current findings suggest that patients with prostate cancer who receive radiation therapy are at an increased risk of being diagnosed with certain cancers, particularly cancers of the bladder and rectum.","[3.0, 1.0, 1.0, 1.0, 1.0]",Medicine,test,1.4,news,http://www.sciencedaily.com/releases/2014/05/140530124422.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29 10.1126/science.aao4408,Medicine_201,It turned out that refugees with particular backgrounds or skills achieved better outcomes in some locations than others.,Various mapping functions can be used.,"They found that the refugees' eventual economic self-sufficiency depended on a combination of their individual characteristics, such as education level and knowledge of English, and where they were resettled within the country. It turned out that refugees with particular backgrounds or skills achieved better outcomes in some locations than others. In 2016 alone, about 65.6 million people were forced to flee their homes.","A separate model was fit for subgroups of refugees assigned to each location, thus yielding different models for each location and allowing for the discovery of refugee/location synergies. Various mapping functions can be used. Our preferred case-level metric was the predicted probability that at least one refugee in the case would find employment at the location in question.","[3.0, 1.0, 2.0, 1.0]",Medicine,test,1.75,news,http://www.futurity.org/refugee-resettlement-algorithm-1658522-2/ 10.1136/bmjopen-2015-008566,Medicine_208,Most (77 percent) respondents said they would like their clinic to allow them to record medical encounters.,"They feared that covertly recording an encounter ""would be a breach of trust"" (interviewee 12) between the patient and clinician, and that as a patient, ""you owe the clinician an explanation"" (interviewee 13) for wanting to record.","The survey found 15 percent of respondents covertly recorded a medical encounter, with an additional 11 percent of respondents indicating they know of someone who had. Thirty-five percent of respondents said they would consider recording a medical visit with a health professional, and a further 34 percent indicated a willingness to record only requesting permission from the clinician. Most (77 percent) respondents said they would like their clinic to allow them to record medical encounters.","The majority of interviewees indicated a desire to record with permission. They feared that covertly recording an encounter ""would be a breach of trust"" (interviewee 12) between the patient and clinician, and that as a patient, ""you owe the clinician an explanation"" (interviewee 13) for wanting to record. Interviewees felt like recording and ""not asking permission would be like subterfuge"" (interviewee 1).","[2.0, 2.0, 1.0, 3.0]",Medicine,test,2.0,news,http://ct.moreover.com/?a=33741021016&p=1pl&v=1&x=JxtI4EUDwJDHNI7Kh9o-4g 10.1210/en.2013-1955,Medicine_212,"""It's very hard to avoid.""",Examples of HG-PIN and prostate adenocarcinoma as well as benign lesions of hyperplasia and SQM are shown in Fig 5 with PSA immunostaining to confirm their human origin and lack of basal cell staining to confirm carcinoma.,"According to the study authors, avoiding the chemical altogether is a next-to impossible feat. ""It's very hard to avoid."" ""The amount of BPA we fed the mice was equivalent to levels ingested by the average person,"" the authors noted.","As previously observed (28), progressive malignancy incidence was noted over time with highest HG-PIN and cancer incidence present at 4 months. Examples of HG-PIN and prostate adenocarcinoma as well as benign lesions of hyperplasia and SQM are shown in Fig 5 with PSA immunostaining to confirm their human origin and lack of basal cell staining to confirm carcinoma. As shown in Table 1 , prostate grafts from animals treated with vehicle during tissue development plus T+E exposure at maturity had an overall incidence of 26% normal grafts, 74% benign lesions and 13% malignant lesions (Note: malignant lesions always co-appeared in grafts containing 16 benign lesions).","[2.0, 1.0, 2.0, 1.0]",Medicine,test,1.5,news,http://www.medicaldaily.com/bpa-exposure-utero-may-triple-risk-prostate-cancer-can-we-do-anything-about-it-266535 10.1007/s11606-016-3760-9,Medicine_213,"Colon cancer screening rates remain suboptimal, despite decades of public health campaigns, public reporting on screening rates, and preventive service reminders in electronic health records, the researchers said, prompting a growing number of private and public health systems to promote options that do not require a face-to-face primary care visit.","The study population was also diverse with regard to sex, race, ethnicity, and insurance coverage, and cared for in four geographically and administratively distinct regional delivery systems.","Individuals don't have to come in to see a doctor to get a cancer screening test done or followed up. Colon cancer screening rates remain suboptimal, despite decades of public health campaigns, public reporting on screening rates, and preventive service reminders in electronic health records, the researchers said, prompting a growing number of private and public health systems to promote options that do not require a face-to-face primary care visit. The FIT and FOBT tests are inexpensive, easy to mail, and simple for patients to complete.","The diversity and size of our study population is also a strength. The study population was also diverse with regard to sex, race, ethnicity, and insurance coverage, and cared for in four geographically and administratively distinct regional delivery systems. The associations we report were robust after controlling for the likelihood of having a PCP visit, as well as in secondary analyses that adjusted for other patient factors known to influence screening and primary care utilization such as age, sex, race, ethnicity, education, and insurance.","[1.0, 1.0, 2.0, 1.0, 3.0]",Medicine,test,1.6,news,http://healthmedicinet.com/news/primary-care-visits-result-in-more-colon-cancer-screening-better-followups/ 10.1073/pnas.1407787111,Medicine_223,They could even see that the lags in connection development with the two task-related networks -- the frontoparietal and ventral attention networks -- were located primarily in two specific areas of the brain.,These advances raise possibilities for investigating maturational lag in ADHD in the developing ICN architecture of the brain .,"The researchers found lags in development of connection within the internally-focused network, called the default mode network or DMN, and in development of connections between DMN and two networks that process externally-focused tasks, often called task-positive networks, or TPNs. They could even see that the lags in connection development with the two task-related networks -- the frontoparietal and ventral attention networks -- were located primarily in two specific areas of the brain. The new findings mesh well with what other researchers have found by examining the physical structure of the brains of people with and without ADHD in other ways.","Our finding of maturational lag specifically in connections within and between these networks suggests a developmental etiology for the deficits proposed in these models. These advances raise possibilities for investigating maturational lag in ADHD in the developing ICN architecture of the brain . Thus, conventional seedbased strategies are likely to produce summary measures that do not capture underlying fine-grained patterns of variation or can miss trends that are detectable only when looking across large populations of connections.","[3.0, 2.0, 4.0, 3.0, 4.0]",Medicine,test,3.2,news,http://www.newswise.com/articles/slow-to-mature-quick-to-distract-adhd-brain-study-finds-slower-development-of-key-connections 10.1098/rspb.2014.2335,Medicine_227,"The variation in infection intensity observed within some North American species, such as the little brown bat, may be a hopeful sign, he said.",Infection prevalence in early autumn when bats returned to infected hibernacula to swarm was between 5% and 50% for the six species ( figure 2) .,"Their results pointed toward host resistance and did not support the other hypotheses, Hoyt said. The variation in infection intensity observed within some North American species, such as the little brown bat, may be a hopeful sign, he said. Overall, little brown bats had much higher levels of infection than Asian bats, but some individual little brown bats had relatively low fungal loads.","Serial dilutions of the DNA from 10 ng to 1000 fg were prepared and analysed with IGS qPCR, resulting in a significant curve from 17.33 to 30.74 C t (ng of P. destructans ¼ 23.348*C t þ 22.049, r 2 ¼ 0.986). Infection prevalence in early autumn when bats returned to infected hibernacula to swarm was between 5% and 50% for the six species ( figure 2) . Surprisingly, prevalence decreased during the autumn for M. lucifugus at all three sites where this species was sampled multiple times, and more limited data for other species also suggested a decline in prevalence during this season (figure 2 and the electronic supplementary material, table S1), despite high contact rate during promiscuous mating.","[2.0, 3.0, 3.0, 4.0]",Medicine,test,3.0,news,http://www.science20.com/news_articles/bats_in_asia_found_to_have_resistance_to_whitenose_syndrome_fungus-167607 10.1098/rsbl.2018.0484,Medicine_237,"""Humpback whales seemed to stop singing temporarily rather than modifying sound characteristics of their song under the noise, generated by a passenger-cargo liner,"" the authors of the PLOS ONE paper said in a statement.","Increases in ship noise, both within and below the dolphins' call bandwidth, resulted in higher dolphin whistle frequencies and a reduction in whistle contour complexity, an acoustic feature associated with individual identification.","But it's clear that the sounds are changing behaviors, the authors said. ""Humpback whales seemed to stop singing temporarily rather than modifying sound characteristics of their song under the noise, generated by a passenger-cargo liner,"" the authors of the PLOS ONE paper said in a statement. ""Ceasing vocalization and moving away could be cost-effective adaptations to the fast-moving noise source.""","Elevated ambient noise levels were mainly caused by ship noise. Increases in ship noise, both within and below the dolphins' call bandwidth, resulted in higher dolphin whistle frequencies and a reduction in whistle contour complexity, an acoustic feature associated with individual identification. Consequently, the noiseinduced simplification of dolphin whistles may reduce the information content in these acoustic signals and decrease effective communication, parent -offspring proximity or group cohesion.","[1.0, 2.0, 2.0, 2.0]",Medicine,test,1.75,news,http://ct.moreover.com/?a=37506312271&p=1pl&v=1&x=tVLYFtj8zqmMByb4LTmdbQ 10.1098/rsbl.2018.0484,Medicine_239,"In other words, the dolphins whistled more, but with much less complexity.","In addition to modifying the shape, dolphin whistles were also higher frequency during increased broadband and 2.5 kHz TOL ambient noise immediately prior to the call.","What they found was that the increases in vessel noises resulted in higher whistle frequencies with reductions in complexity. In other words, the dolphins whistled more, but with much less complexity. Analyzing the data, the researchers found that with background noise, the dolphins' typically complex whistles essentially flatlined.","The ambient noise environment could also affect vocal learning, as young animals exposed to elevated noise may hear adjusted calls from conspecifics . In addition to modifying the shape, dolphin whistles were also higher frequency during increased broadband and 2.5 kHz TOL ambient noise immediately prior to the call. Increased low-frequency ambient noise may be causing dolphins to change their vocalization behaviour to avoid or compensate for masking.","[2.0, 3.0, 5.0, 4.0, 4.0]",Medicine,test,3.6,news,http://ct.moreover.com/?a=37527595797&p=1pl&v=1&x=I3-Y0zFdrh-3KNec4pO_bg 10.1093/sysbio/syq054,Medicine_244,"This implies that for 20 million years before dinosaurs became extinct, early versions of primates also lived and evolved.","Compared with two recent molecular studies of primate divergence dates Young 2006, 2008) , the majority of our estimates are somewhat older (Fig.","Under the new estimate, Toumai would fall within the period after the human lineage split from chimpanzees, Martin said. This implies that for 20 million years before dinosaurs became extinct, early versions of primates also lived and evolved. It challenged the accepted theory that primates and other mammals didn't really thrive on the planet until dinosaurs were gone.","Thus, the relatively low (compared with other nodes) discrepancy between mean model estimate and fossil date for node t 13 (34.6%; Table 5 ) may reflect the effect of the near-total absence of a crown strepsirrhine fossil record on both dates rather than relative congruence between the two. Compared with two recent molecular studies of primate divergence dates Young 2006, 2008) , the majority of our estimates are somewhat older (Fig. In most cases, the increases suggested discrepancies between estimated divergence dates and the oldest known fossil representative of a clade.","[1.0, 4.0, 2.0, 4.0]",Medicine,test,2.0,news,http://www.usnews.com/science/articles/2010/11/08/new-statistical-model-moves-human-evolution-back-3-million-years 10.1186/1472-6785-14-23,Medicine_258,"When the creosote was a new addition to the diet of individual N.bryanti woodrats, they had different reactions.",The response of the naïve woodrat population to creosote bush was indicative of extreme physiological stress.,"We expected a huge list of genes -- instead we found very few."" When the creosote was a new addition to the diet of individual N.bryanti woodrats, they had different reactions. They exhibited signs of severe stress, showing that because they hadn't been exposed to the diet, the genes to detoxify it hadn't been switched on.","Although only one detoxification gene (an aldo-keto reductase) was induced by both experienced populations, these populations converged upon functionally equivalent strategies to biotransform the PSCs of creosote bush by constitutively expressing aldehyde and alcohol dehydrogenases, Cytochromes P450s, methyltransferases, glutathione S-transferases and sulfotransferases. The response of the naïve woodrat population to creosote bush was indicative of extreme physiological stress. Major evolutionary dietary shifts seem to be enabled by an underlying change in biotransformation enzymes .","[3.0, 5.0, 2.0, 2.0, 4.0]",Medicine,test,3.2,news,http://www.sciencedaily.com/releases/2014/08/140815102324.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29 10.1098/rstb.2018.0272,Medicine_262,"According to the study, an HRE that occurs on July 1 results in 70 percent fewer disease cases compared to an HRE that occurs on June 1.","B 374: 20180272 damming and river rerouting were a factor, other important drivers were the disruption of vector control activities and local population displacement that led to increased exposure to mosquitoes .","The study, which appears in Philosophical Transactions of the Royal Society B, finds that the risk of a disease outbreak is highest if the HRE occurs early in the transmission season, or the period of time when mosquitoes are able to pass on the virus to humans. According to the study, an HRE that occurs on July 1 results in 70 percent fewer disease cases compared to an HRE that occurs on June 1. ""The warmer it is, the faster an infected mosquito will be able to transmit the virus.","The result was a 4700% increase in the incidence of malaria in the worst affected canton over the average monthly rate for the pre-earthquake period. B 374: 20180272 damming and river rerouting were a factor, other important drivers were the disruption of vector control activities and local population displacement that led to increased exposure to mosquitoes . The evidence from flood events elsewhere underlines the importance of the combination of conditions faced by the displaced population.","[1.0, 1.0, 1.0]",Medicine,test,1.0,news,https://www.futurity.org/mosquito-borne-disease-rainfall-2054692-2/ 10.1038/nmat4357,Medicine_266,"As the cells moved, their push-pull motion caused movement in the gel as well.",Statistical analyses of these motions confirm that such a layer is solid-like and jammed.,"The videos, shown above, show that the normal cells are nearly pentagon-shaped and are jammed--they hardly move at all--while the asthmatic cells become more spindle shaped and are unjammed--they constantly move and swirl. As the cells moved, their push-pull motion caused movement in the gel as well. Next steps Now that it's known that epithelial cells in asthmatic airways are oddly shaped and are not jammed, scientists have to figure out why it's happening--whether it's asthma causing the cells to unjam, or if it's the unjamming of these cells that causes asthma.","Cellular motions are relatively small, cellular rearrangements among neighbouring cells are rare, and each cell remains virtually caged by those immediate neighbours. Statistical analyses of these motions confirm that such a layer is solid-like and jammed. 1 ) is sufficient to trigger large cellular motions and cooperative cellular rearrangements.","[3.0, 2.0, 1.0, 3.0]",Medicine,test,2.25,news,http://www.technology.org/2015/08/12/no-traffic-jams-asthmatic-cells/ 10.1098/rsbl.2018.0484,Medicine_272,The researchers found that ambient noise had a significant effect on the whistle characteristics.,"Increases in ship noise, both within and below the dolphins' call bandwidth, resulted in higher dolphin whistle frequencies and a reduction in whistle contour complexity, an acoustic feature associated with individual identification.","""Nobody wants to live in a noisy neighborhood. The researchers found that ambient noise had a significant effect on the whistle characteristics. With background noise, such as the low frequency chug-chugging of a ship's engine, their usually complex whistle signatures flatlined.","Elevated ambient noise levels were mainly caused by ship noise. Increases in ship noise, both within and below the dolphins' call bandwidth, resulted in higher dolphin whistle frequencies and a reduction in whistle contour complexity, an acoustic feature associated with individual identification. Consequently, the noiseinduced simplification of dolphin whistles may reduce the information content in these acoustic signals and decrease effective communication, parent -offspring proximity or group cohesion.","[4.0, 4.0, 4.0, 2.0, 3.0]",Medicine,test,3.4,news,http://ct.moreover.com/?a=37493457753&p=1pl&v=1&x=jtPjsr4mv_Y4URYKqaubIQ 10.1136/bmjopen-2015-008566,Medicine_278,"Out of 130 survey respondents, 128 answered questions regarding their experience and views on these covert recordings.","Of the 161 eligible respondents, 130 completed the survey.","1 in 5 patients no strangers to covertly recording medical visits Twenty-six percent of patients admitted to secretly recording their clinicians or knowing someone who did, according to a survey published in BMJ Open. Out of 130 survey respondents, 128 answered questions regarding their experience and views on these covert recordings. Here are three survey findings.","Seven were under 18 years old, and therefore ineligible. Of the 161 eligible respondents, 130 completed the survey. There were no significant differences in gender, age or educational attainment between individuals who completed the survey and those who did not.","[2.0, 4.0, 2.0, 4.0]",Medicine,test,3.0,news,http://ct.moreover.com/?a=33741021016&p=1pl&v=1&x=JxtI4EUDwJDHNI7Kh9o-4g 10.1073/pnas.1719233115,Medicine_284,The same effect can also be found in small communities where are simply fewer options for people to interact with.,"Most individuals (∼98%) have a value of µ > 0, meaning that their circles show the standard structure (Fig.",The researchers predicted this effect using a mathematical theory and then found that it held true in actual data gathered on the personal networks of isolated immigrant communities in Spain. The same effect can also be found in small communities where are simply fewer options for people to interact with. This is a notion the researchers point out that I can vouch for from personal experience.,"In this community we anticipate that most individuals will follow the standard regime, as in previous studies . Most individuals (∼98%) have a value of µ > 0, meaning that their circles show the standard structure (Fig. These values of µ ( Fig.","[1.0, 1.0, 1.0, 1.0]",Medicine,test,1.0,news,http://ct.moreover.com/?a=34615793773&p=1pl&v=1&x=B9OeehCkV4Axi__oIw0XTg 10.1002/cncr.28769,Medicine_286,"But when researchers looked at patients who received external beam radiation therapy, they found these patients were estimated to be 70 percent more likely to be diagnosed with a rectal cancer and 40 percent more likely for bladder cancer than the general public.",There were no cancers for which the relative risk estimates among white men with prostate cancer were higher than those for black men with prostate cancer.,"As a whole, men diagnosed with prostate cancer were at a lower risk of developing a second cancer. But when researchers looked at patients who received external beam radiation therapy, they found these patients were estimated to be 70 percent more likely to be diagnosed with a rectal cancer and 40 percent more likely for bladder cancer than the general public. Radiation therapy is a standard treatment for prostate cancer and the researchers stress that their findings should not prohibit anyone from choosing this treatment, in particular men who are not good candidates for surgery.","It is noteworthy that there was a reversal in the direction of the SIRs for chronic lymphocytic leukemia and colon cancer, in which black men with prostate cancer had significant increase in the risk for both cancers (SIR 5 1.27 and SIR 5 1.10, respectively) compared with the general population, whereas white men with prostate cancer had a significantly reduced risk (SIR 5 0.87 and SIR 5 0.88, respectively). There were no cancers for which the relative risk estimates among white men with prostate cancer were higher than those for black men with prostate cancer. Compared with men who did not receive radiation, men who received EBRT were significantly more likely than the general population to be diagnosed with rectal cancer (SIR radiation 5 1.70 vs SIR noradiation 5 0.74; P < .0001) and bladder cancer (SIR radiation 5 1.42 vs SIR noradiation 5 0.76; P < .0001).","[1.0, 1.0, 1.0, 1.0, 1.0]",Medicine,test,1.0,news,http://www.sciencedaily.com/releases/2014/05/140530124422.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29 10.1186/s13287-015-0250-7,Medicine_296,Phase contrast microscopy revealed that cells with fibroblast-like appearance were predominant in the culture.,"Moreover, residual bodies (lipofuscin pigment granules) were also visible within the cytoplasm of these cells (Fig.","Tissues from equine cadaver ligaments up to 72 hours of post-mortem: a promising reservoir of stem cells. Phase contrast microscopy revealed that cells with fibroblast-like appearance were predominant in the culture. Differentiation assays proved that EC-MSCs are able to differentiate towards mesodermal lineages (osteogenic, adipogenic, chondrogenic).","However, some cells at P3 and P20 appeared to have outgrowing extensions (Fig. Moreover, residual bodies (lipofuscin pigment granules) were also visible within the cytoplasm of these cells (Fig. The possibility that cadavers may represent, for tissue maintenance and regeneration, an alternative source of stem cells, is very exciting.","[1.0, 4.0, 2.0, 2.0]",Medicine,test,2.25,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/6X1w7O2uQ6Y/ 10.1073/pnas.1508431112,Medicine_299,"How brain waves entrain to music This image, taken from an MEG reading, shows a musicianaEUR(tm)s brain more strongly entraining to BeethovenaEUR(tm)s unhurried Sonata No.","As the entrainment mechanism occurs for a wide range of acoustic stimuli, we find it unlikely to be following beat or meter in music: such clear groupings do not exist in other stimulus types.","And itaEUR(tm)s not just apes that respond to song. How brain waves entrain to music This image, taken from an MEG reading, shows a musicianaEUR(tm)s brain more strongly entraining to BeethovenaEUR(tm)s unhurried Sonata No. It turns out, the answer has a lot to do with timing.","This methodological choice allows us to study the rate of the music without delving into the complexities of beat and meter, which can shift nonmonotonically with increasing overall rate (i.e., faster notes are often arranged into larger groupings). As the entrainment mechanism occurs for a wide range of acoustic stimuli, we find it unlikely to be following beat or meter in music: such clear groupings do not exist in other stimulus types. We demonstrate that cortical oscillatory activity in both low (<8 Hz) and high (15-30 Hz) frequencies is tightly coupled to behavioral performance in musical listening, in a bidirectional manner.","[2.0, 3.0, 3.0, 2.0, 2.0]",Medicine,test,2.4,news,http://healthmedicinet.com/news/the-neuroscience-of-musical-perception-bass-guitars-and-drake/ 10.1038/s41598-017-11986-4,Medicine_330,"It could be fluctuations in groundwater levels, or changes that could provide early warnings for a variety of geohazards such as permafrost thaw, sinkhole formation, and landslides.""","According to values reported in literature, the 2% limit could easily be exceeded by a variety of near-surface V S changes caused by processes such as water content variations (up to 10-15% ) and freeze-thaw transitions of unconsolidated permafrost (up to 70-80% ).","Added Dou: ""We can monitor the near surface really well by using nothing but traffic noise. It could be fluctuations in groundwater levels, or changes that could provide early warnings for a variety of geohazards such as permafrost thaw, sinkhole formation, and landslides."" In all cases, DAS proved to be comparably sensitive to earthquakes as conventional seismometers, despite its higher noise levels.","Although the resolvable depth ranges will be site-specific (depending on the local ambient-noise source field), we expect comparable time-lapse repeatability levels for the well-constrained portions of V S profiles at other locations. According to values reported in literature, the 2% limit could easily be exceeded by a variety of near-surface V S changes caused by processes such as water content variations (up to 10-15% ) and freeze-thaw transitions of unconsolidated permafrost (up to 70-80% ). Therefore, time-lapse V S imaging enabled by DAS can be a powerful tool for seismic monitoring of the near surface.","[3.0, 2.0, 3.0, 4.0]",Medicine,test,3.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/htReOCeV10Y/ 10.1038/ng.3239,Medicine_334,"The researchers discovered that the mutations disrupt the ion channel's function either by cutting the flow of potassium, leading to a loss of function; or by increasing potassium flow, leading to an excess gain of function.","These results establish KCNA2 as a new gene involved in human neurodevelopmental disorders through two different mechanisms, predicting either hyperexcitability or electrical silencing of K V 1.2-expressing neurons.","The researchers discovered that the mutations disrupt the ion channel's function either by cutting the flow of potassium, leading to a loss of function; or by increasing potassium flow, leading to an excess gain of function. Patients demonstrating a loss of function had their first epileptic seizures starting at the age of around one, but the attacks ceased during childhood or in the patient's teenage years. For patients with increased function, however, epileptic seizures began even earlier and recurred into adulthood.","They carried mutations inducing a drastic gain-of-function effect leading to permanently open channels. These results establish KCNA2 as a new gene involved in human neurodevelopmental disorders through two different mechanisms, predicting either hyperexcitability or electrical silencing of K V 1.2-expressing neurons. Therefore, potassium channel genes represent interesting candidates for neurodevelopmental disorders.","[1.0, 1.0, 2.0]",Medicine,test,1.3333333333333333,news,http://www.sciencedaily.com/releases/2015/03/150311081755.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29 10.1016/j.immuni.2017.07.015,Medicine_343,These different concentrations of interleukin 2 signaling drive the cells to turn on different gene programs and develop gene programs similar to those from either effector or memory T cells.,This creates a scenario where metabolically regulated changes in CTCF association and genome interactions might be interpreted in a cell-type-or context-dependent manner depending upon the enhancer landscape present.,"Thus, control sites used during embryo growth were also likely being used to control T cell changes after an immune challenge. These different concentrations of interleukin 2 signaling drive the cells to turn on different gene programs and develop gene programs similar to those from either effector or memory T cells. They found that adding permeable alpha-ketoglutarate to the low interleukin 2 condition induced about a third of the gene program induced by high interleukin 2 relative to low interleukin 2 in T cells, while it inhibited about 10 percent of the genes that were more highly expressed in low interleukin 2 relative to high interleukin 2 conditions.","In order for changes in CTCF binding events that influence genome organization to exert a functional outcome on gene expression, an active enhancer landscape would need to be present in that region. This creates a scenario where metabolically regulated changes in CTCF association and genome interactions might be interpreted in a cell-type-or context-dependent manner depending upon the enhancer landscape present. The IL-2-and aKG-sensitive effector genes in Th1 cells tended to contain regions of H3K27Ac in proximity to the genes that were actively expressed ( Figures 7B and S7B) .","[4.0, 3.0, 3.0, 3.0, 2.0]",Medicine,test,3.0,news,http://healthmedicinet.com/news/how-a-nutrient-glutamine-can-control-gene-programs-in-cells/ 10.1016/j.immuni.2017.07.015,Medicine_345,"They found that adding permeable alpha-ketoglutarate to the low interleukin 2 condition induced about a third of the gene program induced by high interleukin 2 relative to low interleukin 2 in T cells, while it inhibited about 10 percent of the genes that were more highly expressed in low interleukin 2 relative to high interleukin 2 conditions.","In this study, we identified a connection between IL-2-and aKGsensitive metabolic states with CTCF binding dynamics, genome organization, and gene programming events in CD4 + Th1 cells.","These different concentrations of interleukin 2 signaling drive the cells to turn on different gene programs and develop gene programs similar to those from either effector or memory T cells. They found that adding permeable alpha-ketoglutarate to the low interleukin 2 condition induced about a third of the gene program induced by high interleukin 2 relative to low interleukin 2 in T cells, while it inhibited about 10 percent of the genes that were more highly expressed in low interleukin 2 relative to high interleukin 2 conditions. Alpha-ketoglutarate thus appears to be responsible for part, but not all, of interleukin 2's impact on T cell gene programming.","Collectively, the data are suggestive that aKG-sensitive metabolic events promote an initial mechanistic step, including enhancing CTCF binding at select sites, which is subsequently translated into consequences on gene expression in a contextdependent manner. In this study, we identified a connection between IL-2-and aKGsensitive metabolic states with CTCF binding dynamics, genome organization, and gene programming events in CD4 + Th1 cells. The data suggested that aKG-sensitive metabolic events are integrated by selective changes in CTCF genomic distribution, but this is interpreted in a context-dependent manner, which in part is influenced by the enhancer landscape in the cell.","[3.0, 2.0, 3.0, 2.0, 3.0]",Medicine,test,2.6,news,http://healthmedicinet.com/news/how-a-nutrient-glutamine-can-control-gene-programs-in-cells/ 10.1038/nmat4357,Medicine_359,"The videos, shown above, show that the normal cells are nearly pentagon-shaped and are jammed--they hardly move at all--while the asthmatic cells become more spindle shaped and are unjammed--they constantly move and swirl.","When P was 30 cm H 2 O (red filled circles), the overlap decreased to 0.17. d, The four-point susceptibility","But the study showed that, in asthma, the opposite is true. The videos, shown above, show that the normal cells are nearly pentagon-shaped and are jammed--they hardly move at all--while the asthmatic cells become more spindle shaped and are unjammed--they constantly move and swirl. As the cells moved, their push-pull motion caused movement in the gel as well.","c, When P was less than 20 cm H 2 O, the relative overlap of each cell with its initial position was nearly perfect for time intervals ( t) of less than 144 min, as quantified by the ensemble average, Q( t) , close to 1. When P was 30 cm H 2 O (red filled circles), the overlap decreased to 0.17. d, The four-point susceptibility When movements are cooperative, χ 4 ( t) exhibits a peak whose position corresponds roughly to pack lifetime, and whose magnitude corresponds roughly to pack size.","[1.0, 1.0, 1.0, 1.0, 1.0]",Medicine,test,1.0,news,http://www.technology.org/2015/08/12/no-traffic-jams-asthmatic-cells/ 10.1002/cncr.28769,Medicine_361,"""Overall the incidence of these cancers is low.",Racial disparities in prostate cancer risk and mortality are established.,"""Overall the incidence of these cancers is low. As a whole, men diagnosed with prostate cancer were at a lower risk of developing a second cancer. But when researchers looked at patients who received external beam radiation therapy, they found these patients were estimated to be 70 percent more likely to be diagnosed with a rectal cancer and 40 percent more likely for bladder cancer than the general public.","For malignancies with higher incidence among men with prostate cancer, the risk among black prostate cancer survivors was even higher, (eg, bladder and kidney). Racial disparities in prostate cancer risk and mortality are established. The etiology of the racial disparity observed in our study is not evident and may reflect differences in genetic susceptibility or environmental exposures, treatment received, or some combination of these factors.","[2.0, 1.0, 4.0, 3.0]",Medicine,test,2.5,news,http://www.sciencedaily.com/releases/2014/05/140530124422.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29 10.1073/pnas.1610529113,Medicine_376,"The new device, whose design is still being refined by the team, is expected ultimately to look and function very much like existing otoscopes, the devices most doctors currently use to peer inside the ear to look for signs of infection.",Any absorption or scattering of light by the tympanic membrane inevitably decreases the amount of light that can be delivered to the middle ear structures and further decreases the reflected signal intensity as it traverses back to the detector.,"That could drastically reduce the estimated 2 million cases per year in the United States where such infections are incorrectly diagnosed and unnecessary antibiotics are prescribed. The new device, whose design is still being refined by the team, is expected ultimately to look and function very much like existing otoscopes, the devices most doctors currently use to peer inside the ear to look for signs of infection. ""If there's no fluid, there's no chance of an infection.","The enhanced transmission of SWIR light is advantageous for an otoscope, given that light must pass through the tympanic membrane after reflecting off of the middle ear structures, such as the highly reflective ossicles and the promontory, before being detected. Any absorption or scattering of light by the tympanic membrane inevitably decreases the amount of light that can be delivered to the middle ear structures and further decreases the reflected signal intensity as it traverses back to the detector. Absorption beyond 1,300 nm is also evident in the tympanic membrane attenuation spectrum due to water in the tissue.","[2.0, 1.0, 1.0, 2.0, 2.0]",Medicine,test,1.6,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/AT2n-dzqKlk/ 10.1210/en.2013-1955,Medicine_40,"""We believe that BPA actually reprograms the stem cells to be more sensitive to estrogen throughout life, leading to a life-long increased susceptibility to diseases including cancer,"" Prins said.","This implicates BPA exposure as a potential initiating event in human prostate stem-like cells, one that enables promotion by rising estrogens later in life, as occurs in aging men .","Prins found that a third of tissue samples taken from mice fed BPA had either pre-cancerous lesions or prostate cancer, compared to only 12 percent in a control group of mice fed oil. If the prostate stem cells were exposed to BPA before implantation and again as they produced prostate tissue in the mice, 45 percent of the tissue samples had pre-cancerous lesions or cancer. ""We believe that BPA actually reprograms the stem cells to be more sensitive to estrogen throughout life, leading to a life-long increased susceptibility to diseases including cancer,"" Prins said.","It is important to emphasize that the stem cells in the present study were cultured from disease-free prostates of young organ donors making it unlikely that the cells had prior initiating events. This implicates BPA exposure as a potential initiating event in human prostate stem-like cells, one that enables promotion by rising estrogens later in life, as occurs in aging men . This is similar to our previous findings in a rat model (23, 24) and provides strong evidence that these earlier rodent data are directly relevant to the human disease.","[4.0, 2.0, 3.0]",Medicine,test,3.0,news,http://www.healthcanal.com/cancers/46375-bpa-increases-risk-of-cancer-in-human-prostate-tissue.html 10.1007/s10899-015-9539-9,Medicine_405,The results showed that gamblers demonstrated more probability matching behavior and are thus obviously more likely to perceive illusory patterns.,These results suggest that gamblers are more willing to bet impulsively on perceived illusory patterns.,"Such aEUR~probability matchingaEUR(tm) only yields an expected accuracy of 55.6 percent. The results showed that gamblers demonstrated more probability matching behavior and are thus obviously more likely to perceive illusory patterns. Gamblers also scored much lower on the cognitive reflection task, which measures impulsivity.","This difference could account for the difference in probability matching between the samples. These results suggest that gamblers are more willing to bet impulsively on perceived illusory patterns. From a money-maximization perspective, most gambling is irrational: the statistical expectation of losses is greater than that of gains.","[5.0, 5.0, 4.0, 3.0, 5.0]",Medicine,test,4.4,news,http://healthmedicinet.com/news/gambling-is-all-an-illusion/ 10.1098/rsif.2017.0156,Medicine_410,"""While it's true that landing on plant surfaces following escape-induced jumps can result in very high impact forces that challenge adhesive capacity, these can be mitigated by the bending of the leaf and/or stem.""","We show that landing on plant surfaces following escapeinduced jumps can result in very high impact forces that challenge adhesive capacity, but that these are mitigated by the bending of the leaf and petiole.","""However, it is likely that it could slide along the leaf surface following impact, which would reduce the impact force experienced,"" he said. ""While it's true that landing on plant surfaces following escape-induced jumps can result in very high impact forces that challenge adhesive capacity, these can be mitigated by the bending of the leaf and/or stem."" According to Higham, one way to imagine the challenges faced by such geckos in suddenly arresting their falls would be to think of a skydiver reaching terminal velocity and then grabbing a support in mid-fall and stopping without using a parachute to slow down.","In addition to the possibility that the drag coefficient might be modulated mid-air by altering the angle of attack, T. rapicauda may be able to move horizontally, thereby adjusting its glide path to permit the selection of specific landing surfaces. We show that landing on plant surfaces following escapeinduced jumps can result in very high impact forces that challenge adhesive capacity, but that these are mitigated by the bending of the leaf and petiole. Increased understanding of how geckos interact with plant surfaces will yield new insights into how innovations facilitate and/or limit extreme behaviours.","[5.0, 5.0, 5.0, 5.0, 5.0]",Medicine,test,5.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/z-7aAIJrl2Y/ 10.1073/pnas.1503358112,Medicine_412,"When people drank fructose, the food images produced more activity in the orbitofrontal cortex than when they consumed glucose.",We show that the ingestion of fructose compared with glucose resulted in smaller increases in plasma insulin levels and greater brain responses to food cues in the visual cortex and left orbital frontal cortex.,"Fructose may instead activate pathways that increase the appeal of food. When people drank fructose, the food images produced more activity in the orbitofrontal cortex than when they consumed glucose. People who had just consumed fructose were more likely to forgo the delayed payday in favor of food compared with those who had just received glucose (Proc.",Significance Fructose compared with glucose may be a weaker suppressor of appetite. We show that the ingestion of fructose compared with glucose resulted in smaller increases in plasma insulin levels and greater brain responses to food cues in the visual cortex and left orbital frontal cortex. Ingestion of fructose versus glucose also led to greater hunger and desire for food and a greater willingness to give up long-term monetary rewards to obtain immediate high-calorie foods.,"[4.0, 1.0, 4.0, 5.0, 4.0]",Medicine,test,4.0,news,http://www.scientificamerican.com/article/fructose-may-motivate-people-to-seek-out-food/?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciam%2Fmind-and-brain+%28Topic%3A+Mind+%26+Brain%29 10.1073/pnas.1317120111,Medicine_42,"This suggests that marine top predators are important in climate regulation, although they are mostly left out of climate models, Nevitt said.",Our results imply that marine top predators play a critical role in maintaining both ocean health and global climate.,"""The data are really striking,"" said Gabrielle Nevitt, professor of neurobiology, physiology and behavior at UC Davis and co-author on the paper with graduate student Matthew Savoca. This suggests that marine top predators are important in climate regulation, although they are mostly left out of climate models, Nevitt said. ""In addition to studying how these marine top predators are responding to climate change, our data suggest that more attention should be focused on how ecological systems, themselves, impact climate.","This study demonstrates that dimethyl sulfide, a chemical cue involved in global climate regulation, mediates a tritrophic mutualistic interaction between marine apex predators and primary producers. Our results imply that marine top predators play a critical role in maintaining both ocean health and global climate. Our results highlight the need for more collaboration and discussion between micro-and macroscale biologists working on global issues in the Southern Ocean.","[5.0, 3.0, 2.0, 4.0, 5.0]",Medicine,test,3.8,news,http://www.sciencedaily.com/releases/2014/03/140320125545.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29 10.1038/s41380-018-0043-3,Medicine_420,"""In all cohorts, accumulation of pre-adult environmental hits was highly significantly associated with lifetime conviction for violent acts or high psychopathy and aggression-hostility scores as proxies of violent aggression and rule-breaking.","Together, we provide sound evidence of a disease-independent unfortunate relationship between well-defined pre-adult environmental hits and violent aggression, calling for more efficient prevention.","""Our data support the concept of a disease-independent development of violent aggression in people exposed to multiple pre-adult environmental risk factors,"" says Ehrenreich. ""In all cohorts, accumulation of pre-adult environmental hits was highly significantly associated with lifetime conviction for violent acts or high psychopathy and aggression-hostility scores as proxies of violent aggression and rule-breaking. Strikingly, we note that the composition of risk factors is interchangeable.""","Conversely, determination in peripheral blood mononuclear cells of histone-deacetylase1 mRNA as 'umbrella mediator' of epigenetic processes revealed an increase in the high-risk group, suggesting lasting epigenetic alterations. Together, we provide sound evidence of a disease-independent unfortunate relationship between well-defined pre-adult environmental hits and violent aggression, calling for more efficient prevention. Moreover, these environmental risk factors seem to contribute to abnormal behavior and to severity and onset of mental illness [1] , even though different risk factors may have different impact, dependent on the particular neuropsychiatric disease in focus.","[4.0, 5.0, 3.0, 4.0, 1.0]",Medicine,test,5.0,news,http://ct.moreover.com/?a=34142742647&p=1pl&v=1&x=9TJLMEpCdBmvZnP19MuAnw 10.1111/acer.12618,Medicine_426,"""This study has added to the existing literature by establishing the relationship between two sleep variables -- sleep difficulties and hours of sleep -- and the odds of serious alcohol- and drug-related problems in a nationally representative sample.""","However, because substance use was not a focus of the study, the relationships between sleep difficulties and a number of important substance-related problems were not analyzed.","For example, the problems may have an immediate impact of an automobile accident, or may result is a reduction of future job opportunities because of lost educational engagement. ""This study has added to the existing literature by establishing the relationship between two sleep variables -- sleep difficulties and hours of sleep -- and the odds of serious alcohol- and drug-related problems in a nationally representative sample."" Both Wong and Roehrs believe that parents can play a significant role regarding their adolescents' sleep habits.","Another study using ADD HEALTH data reported that the frequency of having trouble falling asleep or staying asleep in the last 12 months at a previous wave increased the likelihood of one or more of the following alcohol-related problems (N = 6,504) -having problems at school or with school work, having problems with friends, having problems with someone they were dating, and getting into a physical fight over the last 12 months due to their drinking at T2 and T3. However, because substance use was not a focus of the study, the relationships between sleep difficulties and a number of important substance-related problems were not analyzed. As we pointed out earlier, national data indicated that many adolescents (as much as 45%) did not get enough sleep .","[3.0, 1.0, 2.0, 3.0, 2.0]",Medicine,test,2.2,news,http://psychcentral.com/news/2015/01/19/kids-poor-sleep-can-up-risk-for-substance-abuse/80122.html 10.1001/jamapsychiatry.2018.1471,Medicine_428,"Compared with the general population, patients who lived through an opioid overdose were 130 times more likely to die of drug-use-related causes in the following year, the researchers found.","The magnitude and pattern of the premature mortality, which varied by patient sex, background level of diagnosed medical conditions, and age group, have implications for the medical and behavioral health management of adults after nonfatal opioid overdose.","Compared with the general population, patients who lived through an opioid overdose were 130 times more likely to die of drug-use-related causes in the following year, the researchers found. These ""lucky ones"" were also 45 times more likely to die of HIV, 40 times more likely to die of chronic respiratory diseases and nearly 30 times more likely to die of viral hepatitis. Risk of suicide was 25 times greater.","Diseases of the circulatory system, cancer, respiratory system, and suicide also made important contributions to the excess deaths. The magnitude and pattern of the premature mortality, which varied by patient sex, background level of diagnosed medical conditions, and age group, have implications for the medical and behavioral health management of adults after nonfatal opioid overdose. The overall increase in all-cause mortality during the first year after nonfatal overdose exceeded most prior estimates of mortality in cohorts of opioid-using or dependent adults.","[5.0, 4.0, 3.0, 1.0, 4.0]",Medicine,test,3.0,news,http://ct.moreover.com/?a=34353087866&p=1pl&v=1&x=eOCnWUGSnPoMqyD_b8Z-9A 10.1111/j.1439-0310.2008.01603.x,Medicine_437,Cuteness helps babies survive.,The baby schema response can have behavioral consequences.,"The longer a child looks at an image, the more interested it is in the object. ""This study will also lead to further research with an impact on real life, namely whether the 'cuteness' of an animal in rescue centres makes them more or less likely to be adopted."" Cuteness helps babies survive.","Cute infants are rated as more likeable, friendly, healthy and competent than the less cute infants Stephan & Langlois 1984; , an effect that may be mediated by the baby schema. The baby schema response can have behavioral consequences. For example, cute infants are looked at longer , and mothers of more attractive infants are more affectionate and playful .","[2.0, 4.0, 4.0, 1.0, 4.0]",Medicine,test,4.0,news,http://www.natureworldnews.com/articles/8157/20140721/children-adorable-dogs-cats-human-faces.htm 10.1016/j.neuroimage.2013.09.038,Medicine_455,The reasons behind the changes in IQ are not clear at this point.,"Importantly, and contrary to conclusions, the association between cortical and cognitive changes in our data was found in brain areas that are relevant for individual differences in general intelligence.","This finding should make people wary of sticking to an early IQ assessment given the role it plays in school entrance criteria, detection of the gifted, as well as in eligibility for social security disability income or even the death penalty. The reasons behind the changes in IQ are not clear at this point. Some of these may be due to programmed developmental trajectories or other factors such as nutrition and education, noted Professor Karama.","Differences between voxel and surface-based morphometry techniques, as well as other methodological differences (e.g., sample size, cognitive tests used, sample representativeness) are likely partly to account for the observed discrepancies. Importantly, and contrary to conclusions, the association between cortical and cognitive changes in our data was found in brain areas that are relevant for individual differences in general intelligence. The associations we observed in sensorimotor areas deserve further study, although they are consistent with extensive evidence showing that the sensorimotor cortex is involved in abstract reasoning, a main subcomponent of general cognitive ability.","[3.0, 3.0, 1.0, 2.0, 3.0]",Medicine,test,2.4,news,http://www.sciencedaily.com/releases/2014/03/140304141734.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29 10.1136/bmjopen-2014-004996,Medicine_456,"Findings revealed that for many, anal heterosex appeared to be ""painful, risky and coercive, particularly for women.""","Fourth, anal sex today appears to be a marker of (hetero)sexual achievement or experience, particularly for men.","Whether in a marriage or a casual fling, sex should always be consensual with respectable boundaries. Findings revealed that for many, anal heterosex appeared to be ""painful, risky and coercive, particularly for women."" Meanwhile, male partners often talked of their expectations to coerce reluctant partners.","Even Alicia's narrative contains some of the apparently coercive features of anal sex that other women report in negative terms, despite Alicia reporting enjoying anal sex. Fourth, anal sex today appears to be a marker of (hetero)sexual achievement or experience, particularly for men. The society which our interviewees inhabit seems to reward men for sexual experience per se ('every hole's a goal') and, to some extent, rewards women for compliance with sexually 'adventurous' acts (enjoyment signifying not being naive, unrelaxed, etc), although women must balance this with the risk to their reputation.","[4.0, 3.0, 4.0, 4.0]",Medicine,test,3.75,news,http://www.scienceworldreport.com/articles/16635/20140815/climate-of-coercion-study-reveals-young-mens-attempts-at-anal-sex.htm 10.1038/nn.4592,Medicine_471,Both conditions are also present in individuals with a mutated CHD8 gene.,We did not identify enrichment with genes downregulated in postmortem ASD cortex.,"""This is critical to understanding the biology of disorders like autism."" Both conditions are also present in individuals with a mutated CHD8 gene. New implications for early and lifelong brain development Analysis of data from mouse brains reveals that CHD8 gene expression peaks during the early stages of brain development.","Finally, we observed enrichment (P = 0.012) between DE upregulated genes and genes associated with immune response that were upregulated in cortex from postmortem ASD brains 24 . We did not identify enrichment with genes downregulated in postmortem ASD cortex. We observed consistent enrichment among up-and downregulated DE genes in Chd8 +/del5 forebrain and up-and downregulated DE genes identified in previous studies (Fig.","[1.0, 1.0, 1.0, 1.0, 1.0]",Medicine,test,1.0,news,http://healthmedicinet.com/news/mice-provide-insight-into-genetics-of-autism-spectrum-disorders/ 10.1016/j.celrep.2014.12.012,Medicine_476,"But this process spirals out of control in lung cancer cells, which scrap too many TIAM1 ties**.","These findings reveal a molecular mechanism by which MET/HGF signaling, whose hyperactivation is associated with invasive growth of many neoplasms, stimulates epithelial cell motility and invasion.","But this process spirals out of control in lung cancer cells, which scrap too many TIAM1 ties**. Targeting this recycling process could stop lung cancer from spreading by keeping the cells stuck firmly together. Targeting this flaw could help stop lung cancer from spreading.""","Failure to degrade TIAM1 or depletion of HUWE1 in cells results in delayed adhesion disassembly and prevents the HGF-induced stimulation of migration and invasion. These findings reveal a molecular mechanism by which MET/HGF signaling, whose hyperactivation is associated with invasive growth of many neoplasms, stimulates epithelial cell motility and invasion. Our findings here suggest that effects of HUWE1 on cell-cell adhesion and invasion via regulating TIAM1 degradation would promote epithelial tumor progression.","[1.0, 3.0, 1.0, 4.0, 2.0]",Medicine,test,2.2,news,http://www.sciencedaily.com/releases/2014/12/141225143556.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29 10.1007/s00109-014-1233-3,Medicine_483,"""But either way, mitochondrial DNA could be a very useful biomarker in the field of aging.""","Furthermore, this association was not driven by any single component of the frailty phenotype, with three out of five frailty characteristics showing statistically significant association with lower mtDNA copy number in whites (Fig.","The investigators say their findings contribute to the scientific understanding of aging and may lead to a test that could help identify at-risk individuals whose physical fitness can be improved with drugs or lifestyle changes. ""But either way, mitochondrial DNA could be a very useful biomarker in the field of aging."" On average, Arking says, subjects who met the criteria for frailty had 9 percent less mtDNA than nonfrail participants.","In a race-stratified analysis of samples from CHS, we observed a statistically significant association between lower mtDNA copy number and frailty, adjusted for age and sex, in whites (OR 0.91, 95 % CI 0.85-0.97, P = 0.005). Furthermore, this association was not driven by any single component of the frailty phenotype, with three out of five frailty characteristics showing statistically significant association with lower mtDNA copy number in whites (Fig. 1) , and a similar trend of association for the remaining characteristics.","[1.0, 2.0, 1.0, 2.0, 1.0]",Medicine,test,1.4,news,http://www.healthcanal.com/blood-heart-circulation/58483-amount-of-mitochondrial-dna-predicts-frailty-and-mortality.html 10.1038/s41467-018-06787-w,Medicine_484,"Binding of DMF prevents the activation loop of the kinase from engaging substrate, and stabilizes an auto-inhibitory aL-helix, thus pointing to an effective, allosteric mechanism of kinase inhibition.","We found that DMF leads to full inhibition of RSK2 CTKD , but at moderate efficacy with an IC 50, app.","DMFreacts covalently as a Michael acceptor to a conserved cysteine residue in the aF-helix of RSK/MSKs. Binding of DMF prevents the activation loop of the kinase from engaging substrate, and stabilizes an auto-inhibitory aL-helix, thus pointing to an effective, allosteric mechanism of kinase inhibition. Very importantly, the team found that dimethyl fumarate reacts covalently with at a specific site of the RSK2 protein, which is found in all the RSK and MSK protein kinases, and that this reaction prevents these protein kinases from becoming activated.","We find that DMF inhibits RSK/MSK kinases primarily by covalent binding to a conserved cysteine residue placed at an allosteric site, and that this interaction is likely to represent an important component of the mechanism of action of DMF as a clinical drug. We found that DMF leads to full inhibition of RSK2 CTKD , but at moderate efficacy with an IC 50, app. of 225 μM, when incubated with RSK2 CTKD prior to ERK2 activation, whereas MMF displayed no inhibition of RSK2 CTKD (Fig.","[2.0, 2.0, 1.0, 4.0, 4.0]",Medicine,test,2.0,news,http://ct.moreover.com/?a=37565454595&p=1pl&v=1&x=KGMtfHGI759cpDyCMF3XwA 10.1038/s41598-018-21604-6,Medicine_492,"Early diagnosis leads to early prevention According to Prof. Moshe Hod, the new research follows a global trend, which ""seeks to establish pregnancy tests in the first trimester, as opposed to today, when most tests are performed in the third trimester.""","These findings suggest the predictive value of circulating small non-coding RNA in the first trimester, warranting further examination, and lay the foundation for producing a novel early non-invasive diagnostic tool for preeclampsia, which could reduce the life-threatening risk for both the mother and fetus.","""These findings indicate the predictive value of circulating small RNA molecules in the first trimester, and lay the foundation for producing a novel early non-invasive diagnostic tool for preeclampsia, which could reduce the life-threatening risk for both the mother and fetus."" Early diagnosis leads to early prevention According to Prof. Moshe Hod, the new research follows a global trend, which ""seeks to establish pregnancy tests in the first trimester, as opposed to today, when most tests are performed in the third trimester."" ""Early testing or prediction will allow doctors to safeguard the health of mother and fetus alike.","Using this classification procedure, we achieved an average AUC value of 0.86. These findings suggest the predictive value of circulating small non-coding RNA in the first trimester, warranting further examination, and lay the foundation for producing a novel early non-invasive diagnostic tool for preeclampsia, which could reduce the life-threatening risk for both the mother and fetus. Therefore, although the cause of PE is yet clear, its origin is early and hence detection is feasible already at weeks 10-14 13 .","[2.0, 2.0, 4.0, 3.0, 4.0]",Medicine,test,3.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/NHoaaIv7Je0/ 10.1073/pnas.1318810111,Medicine_505,"Despite opposite treatments, amphetamine-liking SNPs reduced the risk for developing both diseases, suggesting that dopamine's role is more complex than hypothesized.",We also found that the strength of enrichment among the discordant SNPs was slightly improved in this larger meta-analysis sample (P = 0.016) compared with the results from the PCG1 schizophrenia data.,"These results provide unique genetic evidence for the role of dopamine in schizophrenia and ADHD. Despite opposite treatments, amphetamine-liking SNPs reduced the risk for developing both diseases, suggesting that dopamine's role is more complex than hypothesized. The study also offers a new direction for the analysis of a wide range of similar genetic studies, particularly ones with smaller sample sizes.","When considering only the Swedish schizophrenia sample, we observed borderline significant enrichment at the P ≤ 0.05 threshold (P = 0.067); when we performed the same analysis in the meta-analysis sample (PGC1 schizophrenia + Swedish schizophrenia), we found that the strength of enrichment improved (P = 0.021) compared with the same analysis in the PGC1 schizophrenia sample alone. We also found that the strength of enrichment among the discordant SNPs was slightly improved in this larger meta-analysis sample (P = 0.016) compared with the results from the PCG1 schizophrenia data. In this case, we did not observe a significant enrichment when using only the ADHD replication dataset (PGC2 ADHD); however, we did observe a nearly significant enrichment of discordant direction SNPs (P = 0.060).","[3.0, 3.0, 2.0, 2.0, 2.0]",Medicine,test,2.4,news,http://www.healthcanal.com/genetics-birth-defects/49546-genetic-predisposition-to-liking-amphetamine-reduces-risk-of-schizophrenia-and-adhd.html 10.1001/jamaoncol.2015.0388,Medicine_509,"Of these patients, 35 told the researchers that they use fish oil regularly and 13 used omega-3 fatty acid supplements, according to the study.","Herein we show that fish oil contains substantial levels of 16: 4(n-3), a fatty acid with potent chemotherapy-negating effects in preclinical models, and that intake of low doses of fish As can be seen by the quantities of 16:4(n-3) contained in the ingested fish portions (shown in parentheses in the panel labels), mackerel and herring contained high levels, and salmon and tuna contained low levels.","Of these patients, 35 told the researchers that they use fish oil regularly and 13 used omega-3 fatty acid supplements, according to the study. The researchers found that all tested fish oils, herring and mackerel contained a chemotherapy-negating fatty acid. ""After ingestion of these fish oils or fishes, 16:4(n-3) was rapidly taken up in the plasma of human volunteers,"" the researchers wrote.","Thus, consumption of fish rich in 16:4(n-3) enhanced plasma levels of this PIFA. Herein we show that fish oil contains substantial levels of 16: 4(n-3), a fatty acid with potent chemotherapy-negating effects in preclinical models, and that intake of low doses of fish As can be seen by the quantities of 16:4(n-3) contained in the ingested fish portions (shown in parentheses in the panel labels), mackerel and herring contained high levels, and salmon and tuna contained low levels. oil interferes with chemotherapy activity in mice.","[3.0, 2.0, 4.0, 2.0, 4.0]",Medicine,test,3.0,news,http://www.hngn.com/articles/82280/20150403/fish-oil-during-chemotherapy-actually-hinder-cancer-treatment-new-study.htm 10.1002/aur.1444,Medicine_524,aEURoeWeaEUR(tm)ve shown there is a link.,"There were only weak correlations between free BPA and free MEHP, and with % bound MEHP and % bound BPA in the ASD group (Table 4) .","The study, by researchers at Rowan University School of Osteopathic Medicine (RowanSOM) and Rutgers New Jersey Medical School (NJMS), shows that BPA is not metabolized well in children with ASD. aEURoeWeaEUR(tm)ve shown there is a link. The metabolomics analyses showed the mean number of statistically significant correlations between metabolites detected and total BPA excreted to be approximately three times greater with the ASD group than the controls, and the number of statistical significant correlations with fraction of BPA bound was approximately15 times higher in the children with ASD (p aEURoeOther studies involving rodent data have shown that BPA functions as an endocrine disruptor, but ours is the first to show this in humans and the first to associate it to autism,aEUR Stein said.","With DEHP metabolites, there were no differences in the total amount of metabolites excreted, the difference was in the fraction glucuronidated. There were only weak correlations between free BPA and free MEHP, and with % bound MEHP and % bound BPA in the ASD group (Table 4) . Some correlation is to be expected because both BPA and DEHP excretion reflect exposure to plastics in general.","[1.0, 1.0, 1.0, 3.0]",Medicine,test,1.5,news,http://healthmedicinet.com/news/new-study-links-bpa-exposure-to-autism-spectrum-disorder/ 10.1098/rstb.2011.0307,Medicine_525,"To begin, we can advocate creating a neutral space for representatives of both sides to actually meet, face to face, and listen to each other.","Models of rational behaviour predict many of society's patterns, such as favoured strategies for maximizing profit or likelihood for criminal behaviour in terms of opportunity costs .","In short, facts and figures hurt rather than helped the case. To begin, we can advocate creating a neutral space for representatives of both sides to actually meet, face to face, and listen to each other. People need to be able to articulate for themselves what is sacred.","This includes heroism in battle, and martyrdom, where prospects for personal survival are very low but somewhat higher for those in the group who may be neither kin nor kith. Models of rational behaviour predict many of society's patterns, such as favoured strategies for maximizing profit or likelihood for criminal behaviour in terms of opportunity costs . But the prospects of crippling economic burdens and huge numbers of deaths do not necessarily sway people from their positions on whether going to war, or opting for revolution or resistance, is the right or wrong choice .","[1.0, 1.0, 1.0, 1.0, 1.0]",Medicine,test,1.0,news,http://www.salon.com/2014/01/09/missing_from_the_gun_control_debate_sacred_values_partner/ 10.1038/s41591-018-0275-4,Medicine_576,The mice could no longer recognize a familiar object.,"Among 84 genes analyzed, AdFNDC5 rescued Aβ O-induced changes in expression of six genes, whose expression levels were independently validated by qPCR.","Next, the researchers showed that irisin is both necessary and sufficient for protecting memories from degradation. The mice could no longer recognize a familiar object. The irisin blocked the memory loss that was caused by the amyloid b aggregates.","Infection with AdFNDC5 led to increases in FNDC5/irisin mRNA expression and protein levels in the cortex (Fig. Among 84 genes analyzed, AdFNDC5 rescued Aβ O-induced changes in expression of six genes, whose expression levels were independently validated by qPCR. 7 ), indicating possible protective actions of FNDC5/irisin against aberrant expression of synapse-related genes.","[1.0, 1.0, 3.0, 1.0, 1.0]",Medicine,test,1.4,news,http://ct.moreover.com/?a=38200080664&p=1pl&v=1&x=uEbCXHWQUqrC2BRzf-59SQ 10.1093/hmg/ddy369,Medicine_596,Researchers now hope these new insights will be able to lead to new treatment opportunities for patients with these conditions.,The absence of altered collagen IV mRNA levels provides evidence that PBA is acting through its chemical chaperone activity.,"Research will also be developed to explore how, and if, a similar treatment strategy could be applied to humans with brain bleeding caused by these genetic alterations. Researchers now hope these new insights will be able to lead to new treatment opportunities for patients with these conditions. This work has identified a potential treatment strategy in mice and is the first step in translating this to patients.","Besides a chemical chaperone PBA can also act as a histone deacetylase inhibitor . The absence of altered collagen IV mRNA levels provides evidence that PBA is acting through its chemical chaperone activity. In addition, although PBA has been shown to be able to reduce blood pressure in hypertension (44), it did not affect blood pressure in our model, indicating its effects on ICH is independent of blood pressure.","[1.0, 1.0, 1.0, 1.0, 1.0]",Medicine,test,1.0,news,http://ct.moreover.com/?a=37810594174&p=1pl&v=1&x=Ko_VtjsLWciZ0pbglGdvxg 10.1038/s41467-018-05706-3,Medicine_599,Kepler surmised the pressure of the solar rays caused comets' tails to always point away from the sun.,"Due to its finite aperture, all detected displacements are spatially averaged by the sensor.","The breakthrough confirmed light possesses momentum, an idea first proposed by the great German astronomer Johannes Kepler in 1619. Kepler surmised the pressure of the solar rays caused comets' tails to always point away from the sun. ""We were able to trace the features of those waves back to the momentum residing in the light pulse itself, which opens the door to finally defining and modelling how light momentum exists inside materials.""","These comparisons further suggest that the surface displacement measurements are driven almost exclusively by normal radiation pressure, as opposed to absorption or shear optical forces NATURE COMMUNICATIONS | DOI: 10.1038/s41467-018-05706-3 ARTICLE picometer with a reasonably flat frequency response between 10 kHz and 5 MHz while minimizing ultrasonic and electromagnetic distortion effects. Due to its finite aperture, all detected displacements are spatially averaged by the sensor. The tip is covered by a protective nickel foil, but due to its inadequate reflectivity (R = 73% at 1064 nm) a soft gold foil (R = 99% at 1064 nm, thickness: 20 μm) was inserted between the sensor tip and the substrate to further suppress absorption of the scattered laser pulse and to provide a good contact.","[1.0, 1.0, 1.0, 1.0, 1.0]",Medicine,test,1.0,news,http://ct.moreover.com/?a=34876607083&p=1pl&v=1&x=pSgg2lVYuF5x3rMRFuPP4Q 10.1126/sciadv.1701144,Medicine_609,"It used its short tail as a rudder, and may have used its long neck to direct its swims.","FLB is only found in mammals and birds among extant amniotes, leading to the most basic inference from bone tissue type, that is, that FLB is an indicator of mammalian or avian growth rates .","Rhaetocosaurus featured strong muscles around its flippers, so that all four of them could propel it forward for speedy underwater pursuits of ancient fish. It used its short tail as a rudder, and may have used its long neck to direct its swims. And, despite their success, living in waters all over the world, they all died out after the meteor impact at the end of the Cretaceous.","Growth rate can be inferred from bone histology primarily in two ways: by bone tissue type, such as FLB versus lamellar zonal bone , and by a cyclical growth mark record . FLB is only found in mammals and birds among extant amniotes, leading to the most basic inference from bone tissue type, that is, that FLB is an indicator of mammalian or avian growth rates . The ability to lay down limited amounts of woven bone in early ontogenetic stages (fetus and neonate) cannot be equated with FLB and thus cannot serve as evidence against the hypothesis that under natural conditions, FLB requires a high basal metabolic rates for its formation.","[2.0, 1.0, 2.0, 1.0, 1.0]",Medicine,test,1.4,news,http://ct.moreover.com/?a=32782787371&p=1pl&v=1&x=A7tlQbhYOpv8EnQIBxDgaA 10.1002/cncr.28769,Medicine_69,"As a whole, men diagnosed with prostate cancer were at a lower risk of developing a second cancer.",Second primary malignancies required a minimum 2-month latency period after the primary diagnosis to exclude synchronous primary cancers.,"""Overall the incidence of these cancers is low. As a whole, men diagnosed with prostate cancer were at a lower risk of developing a second cancer. But when researchers looked at patients who received external beam radiation therapy, they found these patients were estimated to be 70 percent more likely to be diagnosed with a rectal cancer and 40 percent more likely for bladder cancer than the general public.","The SEER13 data cover 13.4% of the total US population and 11.%, and 11.3% of the total white and black US population, respectively. Second primary malignancies required a minimum 2-month latency period after the primary diagnosis to exclude synchronous primary cancers. Of these, 44,310 men (10%) developed a second primary malignancy during the observation period (Table 1) .","[2.0, 1.0, 1.0, 3.0]",Medicine,test,1.75,news,http://www.sciencedaily.com/releases/2014/05/140530124422.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29 10.1136/annrheumdis-2013-203804,Medicine_71,"Among the 557 symptomatic participants with foot x-rays, the prevalence of radiographic OA of the foot was 16.7%, or roughly one in six - underscoring that it's a common condition.",The population prevalence of symptomatic radiographic foot OA in adults aged 50 years and over was 16.7% (95% CI 15.3% to 18.0%).,"With 19 years of follow-up, Chingford is far and away the largest and longest longitudinal study of first MTP joint OA. Among the 557 symptomatic participants with foot x-rays, the prevalence of radiographic OA of the foot was 16.7%, or roughly one in six - underscoring that it's a common condition. The first MTP joint was the most commonly affected site, with a prevalence of 7.8%, followed by the second cuneometatarsal joint (CMJ) at 6.8%, the talonavicular joint (TNJ) at 5.2%, the navicular first cuneiform joint (NCJ) at 5.2%, and the first CMJ at 3.9%.","Population prevalence of symptomatic radiographic foot OA Population prevalence estimates were almost identical in the baseline responder population and the total baseline eligible mailed population, hence the latter data are presented. The population prevalence of symptomatic radiographic foot OA in adults aged 50 years and over was 16.7% (95% CI 15.3% to 18.0%). The most commonly affected joint was the 1st MTPJ (7.8%; 95% CI 6.7% to 8.9%), followed by the 2nd CMJ (6.8%; 95% CI 5.7% to 7.8%), TNJ (5.8%; 95% CI 4.8% to 6.9%), NCJ (5.2%; 95% CI 4.0% to 6.4%) and 1st CMJ (3.9%; 95% CI 2.9% to 4.9%) (table 3) .","[4.0, 5.0, 4.0, 4.0]",Medicine,test,4.25,news,http://ct.moreover.com/?a=39498153871&p=1pl&v=1&x=ABngbXsk5KufxyHrE-m2mg 10.1002/cncr.28769,Medicine_91,"As a whole, men diagnosed with prostate cancer were at a lower risk of developing a second cancer.","In the 2 to 11 months after prostate cancer diagnosis, there was an increased risk of urinary bladder, kidney, thyroid, and endocrine system cancers and of lymphoma (including both Hodgkin and non-Hodgkin lymphoma).","""Overall the incidence of these cancers is low. As a whole, men diagnosed with prostate cancer were at a lower risk of developing a second cancer. But when researchers looked at patients who received external beam radiation therapy, they found these patients were estimated to be 70 percent more likely to be diagnosed with a rectal cancer and 40 percent more likely for bladder cancer than the general public.","Because the data cover a wide period of time, during which diagnostic and Repeat analyses removing those men who had prostate cancer initially diagnosed as distant stage disease did not materially change the risk estimates (data not shown). In the 2 to 11 months after prostate cancer diagnosis, there was an increased risk of urinary bladder, kidney, thyroid, and endocrine system cancers and of lymphoma (including both Hodgkin and non-Hodgkin lymphoma). At >120 months from diagnosis, the risk was decreased for all of these malignancies among all patients (see online Supporting Information)","[2.0, 3.0, 1.0, 1.0]",Medicine,test,1.75,news,http://www.sciencedaily.com/releases/2014/05/140530124422.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29 10.1186/s13287-015-0250-7,Medicine_98,"CONCLUSIONS: Our findings raise the prospect that the tissues harvested from equine ligaments up to 72 hours of post-mortem represent an available reservoir of specific stem cells.","The present work is the first, in both animal and human, to show that tissues harvested from cadaveric ligaments up to 72 hours postmortem represent an available reservoir of specific stem cell populations.","Furthermore, TEM analysis confirmed the stemness of EC-MSCs and identified some cells with a typical neuronal morphology. CONCLUSIONS: Our findings raise the prospect that the tissues harvested from equine ligaments up to 72 hours of post-mortem represent an available reservoir of specific stem cells. EC-MSCs could be a promising alternative source for tissue engineering and stem cell therapy in equine medicine.","Taking these observations into account, fundamental and clinical research studies are now required to investigate whether MSCs isolated from equine cadavers are suitable, abundant, and readily available to be used in future clinical applications. The present work is the first, in both animal and human, to show that tissues harvested from cadaveric ligaments up to 72 hours postmortem represent an available reservoir of specific stem cell populations. SLs were confirmed free of any damage following examination of the tissues both macroscopically and microscopically.","[4.0, 4.0, 5.0, 5.0, 5.0]",Medicine,test,4.6,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/6X1w7O2uQ6Y/ 10.1001/jama.2014.7587,Medicine_tweet_112,#Endoscopy News: Initial Cholecystectomy vs Sequential Common Duct Endoscopic Assessmen... ,"Although a thorough cost analysis was beyond the scope of the present study, the significantly shorter length of hospital stay and fewer common duct investigations in the study group, coupled with the similar complication rates between the 2 groups, predicts substantial savings when using a cholecystectomy-first strategy.",#Endoscopy News: Initial Cholecystectomy vs Sequential Common Duct Endoscopic Assessmen... ,"Of note, 1-and 6-month follow-ups showed excellent quality of life and no statistically significant difference between groups. Although a thorough cost analysis was beyond the scope of the present study, the significantly shorter length of hospital stay and fewer common duct investigations in the study group, coupled with the similar complication rates between the 2 groups, predicts substantial savings when using a cholecystectomy-first strategy. Both result in similar outcomes.","[2.0, 1.0, 4.0, 3.0, 3.0]",Medicine,test,2.6,tweets,486614848394915841 10.1136/annrheumdis-2013-203804,Medicine_tweet_114,Prevalence of symptomatic radiographic foot OA in older adults: findings from the Clinical Assessment of the Foot ,"In addition, after excluding inflammatory arthritis, 129 clinic attenders had disabling foot pain but did not meet criteria for radiographic foot OA.",Prevalence of symptomatic radiographic foot OA in older adults: findings from the Clinical Assessment of the Foot ,"Again, the 1st MTPJ was most commonly affected (n=58), followed by the 2nd CMJ (n=52), TNJ (n=41), NCJ (n=24) and 1st CMJ (n=15). In addition, after excluding inflammatory arthritis, 129 clinic attenders had disabling foot pain but did not meet criteria for radiographic foot OA. Seventy-eight (60%) of these had grade 1 osteophyte or joint space narrowing in one or more joints in either foot.","[4.0, 2.0, 4.0, 3.0, 1.0]",Medicine,test,2.8,tweets,554110301021675520 10.1098/rsbl.2018.0484,Medicine_tweet_119,Noise levels in the world's oceans are on the rise and this new study found that dolphins are...... ,Ambient noise levels are likely to rise in the future as vessel traffic increases and an offshore wind energy facility is proposed.,Noise levels in the world's oceans are on the rise and this new study found that dolphins are...... ,"The study area is adjacent to the shipping lanes into Delaware Bay (electronic supplementary material, figure S1 ) and had ambient noise levels comparable to other coastal areas with frequent vessel traffic . If a vessel is located in a different direction from conspecifics, there may be a decrease in masking (spatial release from masking) , but the observed changes in the whistle signals indicate that the dolphins simplified their calls to counter the masking effects of vessel noise. Ambient noise levels are likely to rise in the future as vessel traffic increases and an offshore wind energy facility is proposed.","[3.0, 4.0, 1.0, 2.0]",Medicine,test,2.5,tweets,1055334577630265344 10.1001/jamaoncol.2015.0388,Medicine_tweet_162,"Could Fish Oil Induce Resistance to Chemotherapy? ","Herein we show that fish oil contains substantial levels of 16: 4(n-3), a fatty acid with potent chemotherapy-negating effects in preclinical models, and that intake of low doses of fish As can be seen by the quantities of 16:4(n-3) contained in the ingested fish portions (shown in parentheses in the panel labels), mackerel and herring contained high levels, and salmon and tuna contained low levels.","Could Fish Oil Induce Resistance to Chemotherapy? ","Thus, consumption of fish rich in 16:4(n-3) enhanced plasma levels of this PIFA. Herein we show that fish oil contains substantial levels of 16: 4(n-3), a fatty acid with potent chemotherapy-negating effects in preclinical models, and that intake of low doses of fish As can be seen by the quantities of 16:4(n-3) contained in the ingested fish portions (shown in parentheses in the panel labels), mackerel and herring contained high levels, and salmon and tuna contained low levels. oil interferes with chemotherapy activity in mice.","[3.0, 4.0, 4.0, 4.0, 4.0]",Medicine,test,3.8,tweets,584078234418941952 10.1016/j.annemergmed.2018.04.007,Medicine_tweet_200,"Proud to work with several members of @username on this important issue. Identification Management and Transition of Care for Patients with Opioid Use Disorder from the ED. Consider this on your next shift! @username @username","Specifically, patients who receive opioid agonist therapy as part of treatment for opioid use disorder have a decreased chance of fatal overdose compared with those who receive psychological counseling alone.","Proud to work with several members of @username on this important issue. Identification Management and Transition of Care for Patients with Opioid Use Disorder from the ED. Consider this on your next shift! @username @username","46 When buprenorphine is used as medication-assisted therapy, follow-up care can be obtained through opioid treatment programs, hospitals, health departments, and other qualified providers, as detailed below. Specifically, patients who receive opioid agonist therapy as part of treatment for opioid use disorder have a decreased chance of fatal overdose compared with those who receive psychological counseling alone. Furthermore, patients receiving maintenance buprenorphine for at least a year require fewer ED visits and hospitalizations compared with those who discontinue buprenorphine.","[4.0, 2.0, 3.0, 4.0]",Medicine,test,3.25,tweets,1004499693999550464 10.1111/acer.12618,Medicine_tweet_203,Poor sleep may lead to drug and alcohol abuse in teens #sleep,"However, because substance use was not a focus of the study, the relationships between sleep difficulties and a number of important substance-related problems were not analyzed.",Poor sleep may lead to drug and alcohol abuse in teens #sleep,"Another study using ADD HEALTH data reported that the frequency of having trouble falling asleep or staying asleep in the last 12 months at a previous wave increased the likelihood of one or more of the following alcohol-related problems (N = 6,504) -having problems at school or with school work, having problems with friends, having problems with someone they were dating, and getting into a physical fight over the last 12 months due to their drinking at T2 and T3. However, because substance use was not a focus of the study, the relationships between sleep difficulties and a number of important substance-related problems were not analyzed. As we pointed out earlier, national data indicated that many adolescents (as much as 45%) did not get enough sleep .","[2.0, 2.0, 2.0, 1.0]",Medicine,test,1.75,tweets,557508117601456128 10.1002/aur.1444,Medicine_tweet_204,"BPA exposure during pregnancy causes oxidative stress in child, mother Mmm... ","There were only weak correlations between free BPA and free MEHP, and with % bound MEHP and % bound BPA in the ASD group (Table 4) .","BPA exposure during pregnancy causes oxidative stress in child, mother Mmm... ","With DEHP metabolites, there were no differences in the total amount of metabolites excreted, the difference was in the fraction glucuronidated. There were only weak correlations between free BPA and free MEHP, and with % bound MEHP and % bound BPA in the ASD group (Table 4) . Some correlation is to be expected because both BPA and DEHP excretion reflect exposure to plastics in general.","[2.0, 2.0, 2.0, 2.0, 2.0]",Medicine,test,2.0,tweets,557643159266930688 10.1136/bmjopen-2015-008566,Medicine_tweet_207,"Research re UK pts who record by G Elwyn et al in BMJ today Maybe up to 15% of consultations now covertly recorded","They feared that covertly recording an encounter ""would be a breach of trust"" (interviewee 12) between the patient and clinician, and that as a patient, ""you owe the clinician an explanation"" (interviewee 13) for wanting to record.","Research re UK pts who record by G Elwyn et al in BMJ today Maybe up to 15% of consultations now covertly recorded","The majority of interviewees indicated a desire to record with permission. They feared that covertly recording an encounter ""would be a breach of trust"" (interviewee 12) between the patient and clinician, and that as a patient, ""you owe the clinician an explanation"" (interviewee 13) for wanting to record. Interviewees felt like recording and ""not asking permission would be like subterfuge"" (interviewee 1).","[2.0, 3.0, 2.0, 1.0, 3.0]",Medicine,test,2.2,tweets,631207880444780545 10.1001/jamapsychiatry.2014.724,Medicine_tweet_211,Troubled childhoods may prompt men to volunteer for military service ,"After adjusting for demographic information, women with a history of military service in both eras had similar patterns of elevated odds for physical abuse, household alcohol abuse, exposure to domestic violence, and emo-",Troubled childhoods may prompt men to volunteer for military service ,"Fewer differences were noted among women from the draft era, with larger proportions of women with a history of military service reporting physical abuse, exposure to domestic violence, and emotional abuse than women without a history of military service. After adjusting for demographic information, women with a history of military service in both eras had similar patterns of elevated odds for physical abuse, household alcohol abuse, exposure to domestic violence, and emo- As the largest US study, to our knowledge, to examine the prevalence of ACEs among men and women by history of military service, our study found an elevated prevalence of ACEs among men and women who have served in the military.","[3.0, 2.0, 1.0, 2.0, 3.0]",Medicine,test,2.2,tweets,492402771455668224 10.1007/s00109-014-1233-3,Medicine_tweet_217,Mitochondrial DNA copy number associated with all-cause mortality in multiethnic analysis ,"Furthermore, this association was not driven by any single component of the frailty phenotype, with three out of five frailty characteristics showing statistically significant association with lower mtDNA copy number in whites (Fig.",Mitochondrial DNA copy number associated with all-cause mortality in multiethnic analysis ,"In a race-stratified analysis of samples from CHS, we observed a statistically significant association between lower mtDNA copy number and frailty, adjusted for age and sex, in whites (OR 0.91, 95 % CI 0.85-0.97, P = 0.005). Furthermore, this association was not driven by any single component of the frailty phenotype, with three out of five frailty characteristics showing statistically significant association with lower mtDNA copy number in whites (Fig. 1) , and a similar trend of association for the remaining characteristics.","[2.0, 1.0, 3.0]",Medicine,test,2.0,tweets,559526430044717056 10.1136/annrheumdis-2013-203804,Medicine_tweet_22,#medicalresearch The population prevalence of symptomatic radiographic foot osteoarthritis in community-dwelling... ,The population prevalence of symptomatic radiographic foot OA in adults aged 50 years and over was 16.7% (95% CI 15.3% to 18.0%).,#medicalresearch The population prevalence of symptomatic radiographic foot osteoarthritis in community-dwelling... ,"Population prevalence of symptomatic radiographic foot OA Population prevalence estimates were almost identical in the baseline responder population and the total baseline eligible mailed population, hence the latter data are presented. The population prevalence of symptomatic radiographic foot OA in adults aged 50 years and over was 16.7% (95% CI 15.3% to 18.0%). The most commonly affected joint was the 1st MTPJ (7.8%; 95% CI 6.7% to 8.9%), followed by the 2nd CMJ (6.8%; 95% CI 5.7% to 7.8%), TNJ (5.8%; 95% CI 4.8% to 6.9%), NCJ (5.2%; 95% CI 4.0% to 6.4%) and 1st CMJ (3.9%; 95% CI 2.9% to 4.9%) (table 3) .","[5.0, 4.0, 3.0, 5.0]",Medicine,test,4.25,tweets,403525722738028544 10.1038/s41591-018-0275-4,Medicine_tweet_227,Irisin rescues synaptic plasticity and memory defects in Alzheimer’s models at @username ,"Among 84 genes analyzed, AdFNDC5 rescued Aβ O-induced changes in expression of six genes, whose expression levels were independently validated by qPCR.",Irisin rescues synaptic plasticity and memory defects in Alzheimer’s models at @username ,"Infection with AdFNDC5 led to increases in FNDC5/irisin mRNA expression and protein levels in the cortex (Fig. Among 84 genes analyzed, AdFNDC5 rescued Aβ O-induced changes in expression of six genes, whose expression levels were independently validated by qPCR. 7 ), indicating possible protective actions of FNDC5/irisin against aberrant expression of synapse-related genes.","[1.0, 1.0, 2.0, 1.0, 4.0]",Medicine,test,1.8,tweets,1082314686962589696 10.1093/hmg/ddy369,Medicine_tweet_257,"beneficial effect of targeting ER stress for #stroke but not #eyedisease #kidneydisease due to collagen IV. stratified medicine Thanks @username @username et al for hard work, great collaboration @username @username. ",The absence of altered collagen IV mRNA levels provides evidence that PBA is acting through its chemical chaperone activity.,"beneficial effect of targeting ER stress for #stroke but not #eyedisease #kidneydisease due to collagen IV. stratified medicine Thanks @username @username et al for hard work, great collaboration @username @username. ","Besides a chemical chaperone PBA can also act as a histone deacetylase inhibitor . The absence of altered collagen IV mRNA levels provides evidence that PBA is acting through its chemical chaperone activity. In addition, although PBA has been shown to be able to reduce blood pressure in hypertension (44), it did not affect blood pressure in our model, indicating its effects on ICH is independent of blood pressure.","[3.0, 3.0, 3.0, 2.0]",Medicine,test,2.75,tweets,1054561438839107585 10.1002/hbm.23447,Medicine_tweet_258,Neuroscience support regarding brain differences in compulsive sexual behaviour ,Whether the difference in amygdala volume is a preexisting trait predisposing individuals to CSB or related to excessive exposure remains to be established.,Neuroscience support regarding brain differences in compulsive sexual behaviour ,Such drug-related neurotoxicity is likely a highly relevant issue in SUD but less of an issue in behavioral addictions. Whether the difference in amygdala volume is a preexisting trait predisposing individuals to CSB or related to excessive exposure remains to be established. Our finding of decreased functional connectivity between amygdala and DLPFC converges with the existing literature on the connectivity in these regions.,"[3.0, 1.0, 2.0, 4.0, 1.0]",Medicine,test,2.2,tweets,792425870610890752 10.1001/jamapsychiatry.2018.1471,Medicine_tweet_26,"Bottom line: Mortality risk remains markedly elevated in the year following nonfatal opioid overdose. Beware suicide, especially amongst women. #FOAMed #FOAMtox ","The magnitude and pattern of the premature mortality, which varied by patient sex, background level of diagnosed medical conditions, and age group, have implications for the medical and behavioral health management of adults after nonfatal opioid overdose.","Bottom line: Mortality risk remains markedly elevated in the year following nonfatal opioid overdose. Beware suicide, especially amongst women. #FOAMed #FOAMtox ","Diseases of the circulatory system, cancer, respiratory system, and suicide also made important contributions to the excess deaths. The magnitude and pattern of the premature mortality, which varied by patient sex, background level of diagnosed medical conditions, and age group, have implications for the medical and behavioral health management of adults after nonfatal opioid overdose. The overall increase in all-cause mortality during the first year after nonfatal overdose exceeded most prior estimates of mortality in cohorts of opioid-using or dependent adults.","[4.0, 2.0, 2.0, 3.0, 4.0]",Medicine,test,3.0,tweets,1009575727652589569 10.1038/s41598-017-11986-4,Medicine_tweet_270,One of the many uses of distributed acoustic sensing ,This study demonstrates the efficacy of near-surface seismic monitoring using DAS-recorded ambient noise.,One of the many uses of distributed acoustic sensing ,"Our results illustrate that for the top 20 meters the V S models that is well constrained by the data, we obtain time-lapse repeatability of about 2% in the model domain-a threshold that is low enough for observing subtle near-surface changes such as water content variations and permafrost alteration. This study demonstrates the efficacy of near-surface seismic monitoring using DAS-recorded ambient noise. As a result, DAS offers new opportunities for seismic monitoring of the near surface.","[2.0, 3.0, 3.0, 2.0]",Medicine,test,2.5,tweets,939066503105740801 10.1073/pnas.1617948114,Medicine_tweet_271,Hypoxia causes economic effects on a major fishery that was once the most valuable fishery in America ,"Whether researchers can identify impacts from prices depends on the fisheries, the seafood markets, and data availability.",Hypoxia causes economic effects on a major fishery that was once the most valuable fishery in America ,"Departures from stable price relationships could reveal impacts of an ecological disturbance on other fisheries. Whether researchers can identify impacts from prices depends on the fisheries, the seafood markets, and data availability. A substantial premium for soft and peeler crabs exists (the nominal 2014 Chesapeake Bay price for soft and peeler blue crabs was $3.63 per pound compared with $1.61 per pound for hard-shell crabs), but the markets are connected.","[1.0, 3.0, 4.0, 2.0, 2.0]",Medicine,test,2.4,tweets,826842413952094213 10.1126/science.aap7999,Medicine_tweet_284,This is our review on antifungal resistance to raise awareness on the scale of the problem ,"Combining molecular modeling, combinatorial chemistry, and high-throughput screening has the potential to develop chemicals with reduced resistance risk (37) .",This is our review on antifungal resistance to raise awareness on the scale of the problem ,"This situation parallels the situation for antibiotics. Combining molecular modeling, combinatorial chemistry, and high-throughput screening has the potential to develop chemicals with reduced resistance risk (37) . Where target-site mutations confer high levels of resistance, lower doses of antifungals should be favored (40, 41) .","[2.0, 2.0, 3.0, 2.0, 1.0]",Medicine,test,2.0,tweets,997232420041654272 10.1177/0141076813486779,Medicine_tweet_31,Screening fails to lower breast cancer mortality statistics: ,"We conclude that population-based mortality statistics, at least in England, do not show a past benefit of breast cancer screening.",Screening fails to lower breast cancer mortality statistics: ,"In older age groups, a smaller percentage of breast cancer deaths are coded as the underlying cause (for example, 78% in women aged 75-84 years), and figures on breast cancer mortality based on underlying cause alone should be treated with greater caution. We conclude that population-based mortality statistics, at least in England, do not show a past benefit of breast cancer screening. While this does not rule out a benefit at the level of individual women, these effects are not large enough to be detected at the population-level.","[4.0, 5.0, 5.0, 3.0, 5.0]",Medicine,test,4.4,tweets,344498102427852802 10.1073/pnas.1503358112,Medicine_tweet_55,Fructose compared with glucose may be a weaker suppressor of #appetite. ,We show that the ingestion of fructose compared with glucose resulted in smaller increases in plasma insulin levels and greater brain responses to food cues in the visual cortex and left orbital frontal cortex.,Fructose compared with glucose may be a weaker suppressor of #appetite. ,Significance Fructose compared with glucose may be a weaker suppressor of appetite. We show that the ingestion of fructose compared with glucose resulted in smaller increases in plasma insulin levels and greater brain responses to food cues in the visual cortex and left orbital frontal cortex. Ingestion of fructose versus glucose also led to greater hunger and desire for food and a greater willingness to give up long-term monetary rewards to obtain immediate high-calorie foods.,"[1.0, 4.0, 2.0, 3.0]",Medicine,test,2.5,tweets,595611525420818433 10.1098/rsbl.2018.0484,Medicine_tweet_69,Noise levels in the world's oceans are on the rise and this new study found that dolphins are simplifying their calls to be heard over noise from recreational boats and other vessels in nearby shipping lanes ,"In addition to modifying the shape, dolphin whistles were also higher frequency during increased broadband and 2.5 kHz TOL ambient noise immediately prior to the call.",Noise levels in the world's oceans are on the rise and this new study found that dolphins are simplifying their calls to be heard over noise from recreational boats and other vessels in nearby shipping lanes ,"The ambient noise environment could also affect vocal learning, as young animals exposed to elevated noise may hear adjusted calls from conspecifics . In addition to modifying the shape, dolphin whistles were also higher frequency during increased broadband and 2.5 kHz TOL ambient noise immediately prior to the call. Increased low-frequency ambient noise may be causing dolphins to change their vocalization behaviour to avoid or compensate for masking.","[4.0, 4.0, 3.0, 4.0, 3.0]",Medicine,test,3.6,tweets,1055283670355984384 10.1093/gerona/glv133,Medicine_tweet_72,New research provides national estimates of frailty in older people (Free article via @username): ,"In conclusion, our findings support the importance of frailty in late-life health etiology.",New research provides national estimates of frailty in older people (Free article via @username): ,"These data confirm that rapid decline is not inevitable after the mid-80s. In conclusion, our findings support the importance of frailty in late-life health etiology. They bolster evidence for deploying frailty measures as clinical tools to identify at-risk older adults in whom interventions might be targeted.","[5.0, 1.0, 5.0, 4.0, 5.0]",Medicine,test,3.0,tweets,653924007511748608 10.1038/s41380-018-0043-3,Medicine_tweet_82,"A recipe for violence? Children & teenagers who grow up with one or more environmental risk factor such as urbanicity, migration, & substance abuse are more likely to become a violently aggressive adult, study suggests @username","Together, we provide sound evidence of a disease-independent unfortunate relationship between well-defined pre-adult environmental hits and violent aggression, calling for more efficient prevention.","A recipe for violence? Children & teenagers who grow up with one or more environmental risk factor such as urbanicity, migration, & substance abuse are more likely to become a violently aggressive adult, study suggests @username","Conversely, determination in peripheral blood mononuclear cells of histone-deacetylase1 mRNA as 'umbrella mediator' of epigenetic processes revealed an increase in the high-risk group, suggesting lasting epigenetic alterations. Together, we provide sound evidence of a disease-independent unfortunate relationship between well-defined pre-adult environmental hits and violent aggression, calling for more efficient prevention. Moreover, these environmental risk factors seem to contribute to abnormal behavior and to severity and onset of mental illness [1] , even though different risk factors may have different impact, dependent on the particular neuropsychiatric disease in focus.","[4.0, 4.0, 1.0, 4.0, 2.0]",Medicine,test,4.0,tweets,1001058543045357570 10.1186/s13287-015-0250-7,Medicine_easy_42,Immunofluorescence analysis showed a high percentage of positive cells for OCT-4 and SSEA-1.,Immunofluorescence analysis showed a high percentage of positive cells for OCT-4 and SSEA-1.,"Flow cytometry analysis demonstrated that EC-MSCs expressed CD90, CD105, and CD73, while being negative for the leukocyte common antigen CD45. Immunofluorescence analysis showed a high percentage of positive cells for OCT-4 and SSEA-1. Surprisingly, in absence of any stimuli, some adherent cells closely resembling neuronal and glial morphology were also observed.","Flow cytometry analysis demonstrated that EC-MSCs expressed CD90, CD105, and CD73, while being negative for the leukocyte common antigen CD45. Immunofluorescence analysis showed a high percentage of positive cells for OCT-4 and SSEA-1. Surprisingly, in absence of any stimuli, some adherent cells closely resembling neuronal and glial morphology were also observed.",[5],Medicine,test,5.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/6X1w7O2uQ6Y/ 10.1186/s13287-015-0250-7,Medicine_easy_59,Phase contrast microscopy revealed that cells with fibroblast-like appearance were predominant in the culture.,Phase contrast microscopy revealed that cells with fibroblast-like appearance were predominant in the culture.,"Tissues from equine cadaver ligaments up to 72 hours of post-mortem: a promising reservoir of stem cells. Phase contrast microscopy revealed that cells with fibroblast-like appearance were predominant in the culture. Differentiation assays proved that EC-MSCs are able to differentiate towards mesodermal lineages (osteogenic, adipogenic, chondrogenic).","Results: EC-MSCs were successfully isolated and maintained for 20 passages with high cell viability and proliferation. Phase contrast microscopy revealed that cells with fibroblast-like appearance were predominant in the culture. Differentiation assays proved that EC-MSCs are able to differentiate towards mesodermal lineages (osteogenic, adipogenic, chondrogenic).",[5],Medicine,test,5.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/6X1w7O2uQ6Y/ 10.1001/jamainternmed.2014.7657,Medicine_easy_61,"""More studies need to be conducted to clarify the best testing strategy for low-risk patients being evaluated for chest pain in the ED.",More studies need to be conducted to clarify the best testing strategy for low-risk patients being evaluated for chest pain in the ED.,"The study showed that compared with no testing, EE, MPS and CCTA were associated with higher odds of undergoing cardiac catheterization and revascularization procedures without an accompanying improvement in the odds of having a heart attack. ""More studies need to be conducted to clarify the best testing strategy for low-risk patients being evaluated for chest pain in the ED. Given today's concerns regarding health care cost growth, especially the portion attributable to noninvasive cardiac imaging, and patient safety issues related to radiation exposure as well as overdiagnosis, performing such a study should be a priority,"" the study concludes.","In addition, for every 100 000 patients who undergo CCTA instead of an initial strategy of no testing, approximately 800 individuals will have an unnecessary revascularization procedure performed. More studies need to be conducted to clarify the best testing strategy for low-risk patients being evaluated for chest pain in the ED. A randomized trial comparing a no-testing strategy with different noninvasive testing strategies with an emphasis on hard end points could definitively address this need.",[5],Medicine,test,5.0,news,http://www.sciencedaily.com/releases/2015/01/150126124608.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29 10.1001/jamainternmed.2014.7657,Medicine_easy_67,"Given today's concerns regarding health care cost growth, especially the portion attributable to noninvasive cardiac imaging, and patient safety issues related to radiation exposure as well as overdiagnosis, performing such a study should be a priority,"" the study concludes.","Given today's concerns regarding health care cost growth, especially the portion attributable to noninvasive cardiac imaging, and patient safety issues related to radiation exposure as well as overdiagnosis, performing such a study should be a priority.","""More studies need to be conducted to clarify the best testing strategy for low-risk patients being evaluated for chest pain in the ED. Given today's concerns regarding health care cost growth, especially the portion attributable to noninvasive cardiac imaging, and patient safety issues related to radiation exposure as well as overdiagnosis, performing such a study should be a priority,"" the study concludes. It is time to change our guidelines and practice for treatment of chest pain in low-risk patients.","More studies need to be conducted to clarify the best testing strategy for low-risk patients being evaluated for chest pain in the ED. A randomized trial comparing a no-testing strategy with different noninvasive testing strategies with an emphasis on hard end points could definitively address this need. Given today's concerns regarding health care cost growth, especially the portion attributable to noninvasive cardiac imaging, and patient safety issues related to radiation exposure as well as overdiagnosis, performing such a study should be a priority.",[5],Medicine,test,5.0,news,http://www.sciencedaily.com/releases/2015/01/150126124608.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29 10.1186/s13287-015-0250-7,Medicine_easy_68,"Flow cytometry analysis demonstrated that EC-MSCs expressed CD90, CD105, and CD73, while being negative for the leukocyte common antigen CD45.","Flow cytometry analysis demonstrated that EC-MSCs expressed CD90, CD105, and CD73, while being negative for the leukocyte common antigen CD45.","Differentiation assays proved that EC-MSCs are able to differentiate towards mesodermal lineages (osteogenic, adipogenic, chondrogenic). Flow cytometry analysis demonstrated that EC-MSCs expressed CD90, CD105, and CD73, while being negative for the leukocyte common antigen CD45. Immunofluorescence analysis showed a high percentage of positive cells for OCT-4 and SSEA-1.","Differentiation assays proved that EC-MSCs are able to differentiate towards mesodermal lineages (osteogenic, adipogenic, chondrogenic). Flow cytometry analysis demonstrated that EC-MSCs expressed CD90, CD105, and CD73, while being negative for the leukocyte common antigen CD45. Immunofluorescence analysis showed a high percentage of positive cells for OCT-4 and SSEA-1.",[5],Medicine,test,5.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/6X1w7O2uQ6Y/ 10.1186/s13287-015-0250-7,Medicine_easy_71,"Differentiation assays proved that EC-MSCs are able to differentiate towards mesodermal lineages (osteogenic, adipogenic, chondrogenic).","Differentiation assays proved that EC-MSCs are able to differentiate towards mesodermal lineages (osteogenic, adipogenic, chondrogenic).","Phase contrast microscopy revealed that cells with fibroblast-like appearance were predominant in the culture. Differentiation assays proved that EC-MSCs are able to differentiate towards mesodermal lineages (osteogenic, adipogenic, chondrogenic). Flow cytometry analysis demonstrated that EC-MSCs expressed CD90, CD105, and CD73, while being negative for the leukocyte common antigen CD45.","Phase contrast microscopy revealed that cells with fibroblast-like appearance were predominant in the culture. Differentiation assays proved that EC-MSCs are able to differentiate towards mesodermal lineages (osteogenic, adipogenic, chondrogenic). Flow cytometry analysis demonstrated that EC-MSCs expressed CD90, CD105, and CD73, while being negative for the leukocyte common antigen CD45.",[5],Medicine,test,5.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/6X1w7O2uQ6Y/ 10.1098/rstb.2018.0272,Medicine_easy_83,"Population displacement can also affect the spread of vector-borne disease in a few ways, the researchers found.",Data streams from these sources could be useful to quantify the level of public awareness during emergencies and may provide a useful proxy of the temporal profile of population displacement patterns away from the affected areas.,"Considering that mosquitos have an average lifespan of less than two weeks, that temperature difference can have a dramatic effect on disease outbreaks."" Population displacement can also affect the spread of vector-borne disease in a few ways, the researchers found. When people opt to leave the area, it reduces the number of local infections, while potentially increasing the number of infections elsewhere.","We do not model the latter, but note that it is potentially extremely important. Data streams from these sources could be useful to quantify the level of public awareness during emergencies and may provide a useful proxy of the temporal profile of population displacement patterns away from the affected areas. If these characteristics are correlated with mobility, and if evacuations are voluntary, we would expect Twitter data to overestimate the percentage of the population displaced.",[1],Medicine,test,1.0,news,http://ct.moreover.com/?a=39454767451&p=1pl&v=1&x=t_1mmmyJBvTAz09R9w2bgA 10.1111/desc.12179,Medicine_easy_84,"As such the study, published last week in the journal Developmental Science, opens up new avenues for research into the way language might shape the course of developmental disabilities such as ADHD, difficulties with school, and other attention-related problems.",The four experiments reported here show that hearing the name of an object improves 3-year-old children's ability to find that object in an array.,"Language, the study suggests, is transformative: More so than images, spoken language taps into children's cognitive system, enhancing their ability to learn and to navigate cluttered environments. As such the study, published last week in the journal Developmental Science, opens up new avenues for research into the way language might shape the course of developmental disabilities such as ADHD, difficulties with school, and other attention-related problems. ""If the name of the target object was also said, the children were much faster at finding it and less distracted by the other objects in the scene,"" said Vales, a graduate student in the Department of Psychological and Brain Sciences.","The pattern fits the hypothesis that labeling, by activating categoryspecific shape features of the target in visual working memory, resulted in faster performance with less repetition of the visual information. The four experiments reported here show that hearing the name of an object improves 3-year-old children's ability to find that object in an array. The effect of the object name in speeding children's performance in visual search was found in all experiments that manipulated labeling, with targets and distractors that varied in shape and color or that varied in shape alone, and when the target and distractors were of high and low discriminability.",[1],Medicine,test,1.0,news,http://www.sciencedaily.com/releases/2014/04/140417090838.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29 10.1038/s41598-019-44350-9,Medicine_easy_117,"""Our data clearly suggests that obesity and the Na/K-ATPase oxidant amplification loop plays a role in neurodegeneration,"" said first author Rebecca Pratt, a Ph.D. candidate in the department of biomedical research at Marshall University.","Our results also demonstrated a significant increase in the visceral and subcutaneous fat, liver weight, and heart weight in the mice fed a WD, which was markedly reduced with lenti-adiponectin-GFP-NaKtide treatment ( Table 1) .","The researchers were able to successfully demonstrate through decreased adiposity and an improved metabolic profile the therapeutic potential of targeting NaKtide to the adipocytes. ""Our data clearly suggests that obesity and the Na/K-ATPase oxidant amplification loop plays a role in neurodegeneration,"" said first author Rebecca Pratt, a Ph.D. candidate in the department of biomedical research at Marshall University. ""Even targeting NaKtide to adipocytes alone still showed a whole-body effect, which highlights the much larger role that adipocytes play in obesity and whole body homeostasis.""","The increase in the body weight was significantly attenuated by the transduction of lenti-adiponectin-GFP-NaKtide ( Fig. Our results also demonstrated a significant increase in the visceral and subcutaneous fat, liver weight, and heart weight in the mice fed a WD, which was markedly reduced with lenti-adiponectin-GFP-NaKtide treatment ( Table 1) . Food intake and energy intake did not differ amongst the different experimental groups (Fig.",[1],Medicine,test,1.0,news,http://ct.moreover.com/?a=39358808843&p=1pl&v=1&x=pKbzYhsPxx5njcLIUcmXsA 10.1073/pnas.1317120111,Medicine_easy_160,"This suggests that marine top predators are important in climate regulation, although they are mostly left out of climate models, Nevitt says.",(Figure credit : Allison Bruce.),"""The data are really striking,"" says Gabrielle Nevitt, professor of neurobiology, physiology, and behavior at the University of California, Davis, and co-author of the paper with graduate student Matthew Savoca. This suggests that marine top predators are important in climate regulation, although they are mostly left out of climate models, Nevitt says. ""In addition to studying how these marine top predators are responding to climate change, our data suggest that more attention should be focused on how ecological systems, themselves, impact climate.","Once attracted, the procellariiformes may benefit the phytoplankton by adding limiting nutrients via excretion. (Figure credit : Allison Bruce.) Their contribution of beneficial iron recycled to marine phytoplankton via excretion suggests a chemically mediated link between marine top predators and oceanic primary production.",[1],Medicine,test,1.0,news,http://www.theepochtimes.com/n3/576581-scent-that-guides-seabirds-keeps-climate-cool-too/ 10.1083/jcb.201804028,Medicine_easy_169,These results help to understand autophagy and its underlying molecular processes better.,"Thus, Nyv1 is dispensable for bulk autophagy function.","They also discovered the fourth necessary SNARE, now called Ykt6. These results help to understand autophagy and its underlying molecular processes better. And thanks to their newly-developed in vitro approach, in future it will be possible to identify other proteins that operate in the fusion process.","Both nyv1Δ and WT cells displayed Pho8Δ60 activity ( Fig. Thus, Nyv1 is dispensable for bulk autophagy function. Furthermore, Ykt6 and Sec22 act together with the SNA RE proteins Sso1 and Sec9 in Atg9 trafficking during early steps of autophagy .",[1],Medicine,test,1.0,news,http://ct.moreover.com/?a=34819790734&p=1pl&v=1&x=8aQKBEotEoZ2dQYDB6dLKA 10.1073/pnas.1617948114,Medicine_easy_171,"[REITs] Q2 hedge fund letters, conference, scoops etc The measured size of the dead zone, also called the hypoxic zone, is the 8th largest in the 33-year record and exceeds the 5,770-square-mile average from the past five years.",The effects of fuel prices provide supporting evidence.,"[REITs] Q2 hedge fund letters, conference, scoops etc The measured size of the dead zone, also called the hypoxic zone, is the 8th largest in the 33-year record and exceeds the 5,770-square-mile average from the past five years. With high discharge and nutrient loading this spring and summer, the models predicted a very large hypoxia zone to form during the time of the cruise. This year, the passage of Hurricane Barry prior to the research cruise helped mix the water column over the Louisiana shelf, which proved to be a temporary disruption to the hypoxic zone that had already formed.","Naive quantitybased models using treatment/control comparisons in hypoxic and nonhypoxic areas produce null results, but we find strong evidence of the hypothesized effects in the relative prices: Hypoxia increases the relative price of large shrimp compared with small shrimp. The effects of fuel prices provide supporting evidence. Consequently, analyses of price data, which rely on a market counterfactual, are able to reveal effects of the ecological disturbance that are obscured in quantity data.",[1],Medicine,test,1.0,news,http://ct.moreover.com/?a=39842867384&p=1pl&v=1&x=Z4IJCOyCDUP2xyCqpIQE_Q 10.1073/pnas.1508431112,Medicine_easy_177,"And our conscious ability to apply symbolic meaning to sounds, lyrics and song aEUR"" and to recognize when listening to music that what weaEUR(tm)re listening to is supposed to be music aEUR"" also certainly influences human musical perception.","An ANOVA using the harmonic frequencies (3, 2, and 1.5 Hz) showed a main effect of musical experience [F (1,66) = 12.46, P < 0.001], whereas frequency showed no significant modulation.","How humans perceive music is, of course, far more complicated than simply tuning in to tempo. And our conscious ability to apply symbolic meaning to sounds, lyrics and song aEUR"" and to recognize when listening to music that what weaEUR(tm)re listening to is supposed to be music aEUR"" also certainly influences human musical perception. But the work of Poeppel and others suggests that a tonal time perception hinted at in apes and more fully formed in man could be a prerequisite for discerning a song.","Although we did not predict it, musicians also showed greater tracking at harmonic rates (i.e., 3 Hz for 1.5 nps and 2 Hz for 1 nps) for all conditions but 0.7 nps. An ANOVA using the harmonic frequencies (3, 2, and 1.5 Hz) showed a main effect of musical experience [F (1,66) = 12.46, P < 0.001], whereas frequency showed no significant modulation. Multiple comparisons show significant effects in 1.5 nps (P < 0.05) and 1.0 nps (P < 0.05) but not 0.7 nps (P = 0.16).",[1],Medicine,test,1.0,news,http://healthmedicinet.com/news/the-neuroscience-of-musical-perception-bass-guitars-and-drake/ 10.1073/pnas.1617948114,Medicine_easy_191,There are a few factors at play.,[3],This year's forecasted dead zone would be 50 percent larger than the average seen in the last five years. There are a few factors at play. May 2019 capped off the wettest 12 months in U.S. history.,"Nonhypoxic zones provide counterfactuals for hypoxic zones, differencing out seasonal variation in fishing outcomes shared across hypoxic and nonhypoxic zones. [3] There are alternative-specific constants (δ j ) and covariates that vary over just time X (shrimp price, fuel price), individual and location Y (travel distance), and location and time Z (expected revenue and catch, wave height).",[1],Medicine,test,1.0,news,http://ct.moreover.com/?a=39439090562&p=1pl&v=1&x=UQyrvweU2ra3G62BAmaEDQ 10.1126/sciadv.aat6509,Medicine_easy_198,"The year 2005 was certainly the biggest year for tropical storm and hurricane numbers in the Atlantic since the 1940s and, by some measures, the biggest for at least 150 years.",This is due to the data originally used to formulate these GPIs including these short-lived TCs.,"Thus, it could serve as a tropical cyclone risk benchmark for future hurricane seasons in this basin. The year 2005 was certainly the biggest year for tropical storm and hurricane numbers in the Atlantic since the 1940s and, by some measures, the biggest for at least 150 years. The year-to-year simulated variations of these indices in the climate models were compared to total observed tropical cyclone numbers in 2005, but the models only exceeded the observed 2005 numbers rarely, about 1% of the time, and maximum index values simulated in the models were still comparable to 2005 numbers.","S6) were generally slightly poorer when compared to the observed data, and there was a slight decrease in correlations in all indices except the CGI calculated in ERA. This is due to the data originally used to formulate these GPIs including these short-lived TCs. Figures S8 and S9 show that the variations in the GPIs calculated from the models are very constrained around the mean.",[1],Medicine,test,1.0,news,http://ct.moreover.com/?a=34894577018&p=1pl&v=1&x=VxqXy1WNQjnOFbklii8AEg 10.1038/s41598-017-11986-4,Medicine_easy_210,"The technology can also be used to characterize soil quality, provide information on aquifers, and be integrated into geotechnical studies, he added.",This study demonstrates the efficacy of near-surface seismic monitoring using DAS-recorded ambient noise.,"We were able to pick up very low frequency waves from distant earthquakes as well as the higher frequencies generated by nearby vehicles,"" said Ajo-Franklin. The technology can also be used to characterize soil quality, provide information on aquifers, and be integrated into geotechnical studies, he added. With such a detailed picture of the subsurface, the technology has potential for use in time-lapse studies of soil properties, said Rodriguez Tribaldos.","Our results illustrate that for the top 20 meters the V S models that is well constrained by the data, we obtain time-lapse repeatability of about 2% in the model domain-a threshold that is low enough for observing subtle near-surface changes such as water content variations and permafrost alteration. This study demonstrates the efficacy of near-surface seismic monitoring using DAS-recorded ambient noise. As a result, DAS offers new opportunities for seismic monitoring of the near surface.",[1],Medicine,test,1.0,news,http://ct.moreover.com/?a=38453977742&p=1pl&v=1&x=26BbjL8Ip1FZBYAhXziufw 10.1038/ng.3239,Medicine_easy_220,The degree of mental disability and related problems was greater in the latter group.,Two further individuals presented with a different and more severe epileptic encephalopathy phenotype.,"For patients with increased function, however, epileptic seizures began even earlier and recurred into adulthood. The degree of mental disability and related problems was greater in the latter group. For patients whose potassium flows are too high, there is an immediate treatment option in the form of 4-aminopyridine, an approved drug which specifically blocks the relevant ion channel.",Functional studies of the two mutations associated with this phenotype showed almost complete loss of function with a dominant-negative effect. Two further individuals presented with a different and more severe epileptic encephalopathy phenotype. They carried mutations inducing a drastic gain-of-function effect leading to permanently open channels.,[1],Medicine,test,1.0,news,http://www.sciencedaily.com/releases/2015/03/150311081755.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29 10.1186/1550-2783-5-15,Medicine_easy_238,It may seem counterintuitive to put calories back into your body right after you've spent the effort to burn them off.,"However, there can be considerable differences in the responses observed depending on the intensity of the exercise performed.","A single ounce of cheese has over six grams of high-quality protein. It may seem counterintuitive to put calories back into your body right after you've spent the effort to burn them off. Of course, not all carbs and proteins are created equal; what you eat afterward is nearly as important as the workout itself.","This dependence on oxidative metabolism and involvement of a large muscle mass leads to higher rates of total substrate turnover and under certain conditions, depletion of muscle glycogen in the active muscles. However, there can be considerable differences in the responses observed depending on the intensity of the exercise performed. What is evident is that when milk is compared to carbohydrate based sports drinks, similar responses in many physiological variables are observed during the exercise.",[1],Medicine,test,1.0,news,http://ct.moreover.com/?a=33961713810&p=1pl&v=1&x=vV1InIzRXZ1GWDyDToOjJA 10.1073/pnas.1610529113,Medicine_easy_246,"""If there's no fluid, there's no chance of an infection.","In addition, SWIR light offers greater transmission through biological tissue than visible or NIR light due to decreased scattering of photons .","The new device, whose design is still being refined by the team, is expected ultimately to look and function very much like existing otoscopes, the devices most doctors currently use to peer inside the ear to look for signs of infection. ""If there's no fluid, there's no chance of an infection. But the eardrum basically becomes transparent to our device.""","Moreover, our device is easily translatable to the clinic, as the ergonomics, visual output, and operation are similar to a conventional otoscope. In addition, SWIR light offers greater transmission through biological tissue than visible or NIR light due to decreased scattering of photons . SWIR light thus provides sufficient optical penetration depth to noninvasively interrogate changes in subsurface tissue features, whereas most visible and NIR imaging is limited to superficial structures .",[1],Medicine,test,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/AT2n-dzqKlk/ 10.1038/s41467-019-08640-0,Medicine_easy_248,We found the opposite: Rates are actually higher in coastal areas.,"In that case, any biases in the quantitative measurement due to amplification biases or DNA extraction recoveries should be consistent across the samples.","Knowing where and when nitrogen fixation is occurring will help scientists better quantify coastal waters' ability to absorb and store carbon dioxide and aid in future climate predictions. We found the opposite: Rates are actually higher in coastal areas. Most of this overlooked activity is being driven by microbes known as cyanobacterial diazotrophs that live in coastal waters, the study shows.","However, while recovery of the standard may differ from recovery of natural taxa in the same sample, variation in standard recovery efficiency from sample to sample will reflect differences in starting material, losses during elution, and other processes as long as the same PCR and library preparation protocol is followed. In that case, any biases in the quantitative measurement due to amplification biases or DNA extraction recoveries should be consistent across the samples. Therefore, the 16S rRNA approach is informative when providing the spatial distribution and abundance patterns of diazotrophic taxa.",[1],Medicine,test,1.0,news,http://ct.moreover.com/?a=38604465453&p=1pl&v=1&x=V7606FErQL2Czt5nCH8wLA 10.1038/s41598-017-11986-4,Medicine_easy_263,"Lindsey added: ""Fiber has a lot of implications for earthquake detection, location, and early warning.","Time-for-distance conversion allows strain signals to be recorded at spatially localized regions of the fiber, hence transforming the cable into a densely sampled sensor array.","Additionally, fiber allows for dense spatial sampling, meaning data points are only meters apart, whereas seismometers typically are separated by many kilometers. Lindsey added: ""Fiber has a lot of implications for earthquake detection, location, and early warning. Fiber goes out in the ocean, and it's all over the land, so this technology increases the likelihood that a sensor is near the rupture when an earthquake happens, which translates into finding small events, improved earthquake locations, and extra time for early warning.""","As a result, DAS offers new opportunities for seismic monitoring of the near surface. Time-for-distance conversion allows strain signals to be recorded at spatially localized regions of the fiber, hence transforming the cable into a densely sampled sensor array. DAS generates digital waveforms that are familiar to seismic practitioners, but because DAS is a distributed sensor, waveforms obtained at each channel are not a point measurement but are strains measured over a spatial distance.",[1],Medicine,test,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/htReOCeV10Y/ 10.1002/hbm.23447,Medicine_easy_267,"When I was younger, I definitely think I had a sekh addiction of some kind, yes, that everything could be fixed by sekh.",Whether the difference in amygdala volume is a preexisting trait predisposing individuals to CSB or related to excessive exposure remains to be established.,"When I was younger, I definitely think I had a sekh addiction of some kind, yes, that everything could be fixed by sekh. ""I remember reaching a rock bottom that time I was in the house by myself, and I had those two bottles of wine and was going for the third bottle,"" she said. You might have a problem.'""",Such drug-related neurotoxicity is likely a highly relevant issue in SUD but less of an issue in behavioral addictions. Whether the difference in amygdala volume is a preexisting trait predisposing individuals to CSB or related to excessive exposure remains to be established. Our finding of decreased functional connectivity between amygdala and DLPFC converges with the existing literature on the connectivity in these regions.,[1],Medicine,test,1.0,news,http://ct.moreover.com/?a=34509277595&p=1pl&v=1&x=bD89zlOjQQk5SzDxj0ox4w 10.1111/jcpp.12015,Medicine_easy_302,"For Jill Wolfe's kids, surrogacy seems completely natural.","The SDQ discriminates well between psychiatric and nonpsychiatric samples, and evidence for concurrent validity comes from the high correlations between the total score of the SDQ and other assessments of child psychiatric disorder .","While all the children seemed to be doing well by age 10, Golombok says, the concern is, trouble could crop up later as kids hit their adolescence and are trying to find their identities and place in the world, experts say. For Jill Wolfe's kids, surrogacy seems completely natural. That, the 42-year-old Minneapolis mom says, is because she and her husband began explaining things early.","There was a significant difference between family types for number of siblings, v 2 (6) = 28.84, p < .001, reflecting a lower proportion of surrogacy, egg donation, and donor insemination children than natural conception children with siblings. The SDQ discriminates well between psychiatric and nonpsychiatric samples, and evidence for concurrent validity comes from the high correlations between the total score of the SDQ and other assessments of child psychiatric disorder . Intraclass correlation coefficients ranged from 0.50 to 0.80 .",[1],Medicine,test,1.0,news,http://www.today.com/health/new-study-tracks-emotional-health-surrogate-kids-6C10366818 10.1098/rsbl.2018.0484,Medicine_easy_307,"""They're probably also sharing less information, because they're just trying to be heard over the noise.""",Ambient noise levels are likely to rise in the future as vessel traffic increases and an offshore wind energy facility is proposed.,"""They're probably also sharing less information, because they're just trying to be heard over the noise."" Her research adds to a growing body of evidence that ocean background noise is affecting marine animals -- not just mammals, but other creatures like lobster and cod, as well. Bailey, for one, thinks new laws are in order.","The study area is adjacent to the shipping lanes into Delaware Bay (electronic supplementary material, figure S1 ) and had ambient noise levels comparable to other coastal areas with frequent vessel traffic . If a vessel is located in a different direction from conspecifics, there may be a decrease in masking (spatial release from masking) , but the observed changes in the whistle signals indicate that the dolphins simplified their calls to counter the masking effects of vessel noise. Ambient noise levels are likely to rise in the future as vessel traffic increases and an offshore wind energy facility is proposed.",[1],Medicine,test,1.0,news,http://ct.moreover.com/?a=37564450525&p=1pl&v=1&x=GPAhl021-koi6iwC470hew 10.1093/sysbio/syq054,Medicine_easy_313,It can give scientists a broader perspective for interpreting data.,We find that these age estimates are older than previously reported dates for all but one of these nodes.,"Comparing DNA among related animals can provide a clear picture of how their shared genes evolved over time, giving rise to new and separate species, Martin said. It can give scientists a broader perspective for interpreting data. Under the new estimate, Toumai would fall within the period after the human lineage split from chimpanzees, Martin said.","We find that these age estimates are older than previously reported dates for all but one of these nodes. Conditional on there being no classification or dating error, the fossil's age provides a minimum bound for the divergence time of the evolutionary lineage it represents. The pattern and variability observed in homologous sequences of DNA from different species contain traces of the history of the divergence and evolution of the phylogeny, and mathematical models of evolution can be used to combine our knowledge of genetics with the sequence data to extract information about evolutionary history, particularly divergence times.",[1],Medicine,test,1.0,news,http://www.usnews.com/science/articles/2010/11/08/new-statistical-model-moves-human-evolution-back-3-million-years 10.1001/jamainternmed.2014.7657,Medicine_easy_322,"The study showed that compared with no testing, EE, MPS and CCTA were associated with higher odds of undergoing cardiac catheterization and revascularization procedures without an accompanying improvement in the odds of having a heart attack.","Because of limitations of MarketScan, which does not capture data on mortality, we could not assess for death among our cohort.","Patients who did not undergo initial noninvasive testing were no more likely to experience MI than those who did not receive testing. The study showed that compared with no testing, EE, MPS and CCTA were associated with higher odds of undergoing cardiac catheterization and revascularization procedures without an accompanying improvement in the odds of having a heart attack. ""More studies need to be conducted to clarify the best testing strategy for low-risk patients being evaluated for chest pain in the ED.","We believe that the low rates of MI in all groups within 7 and 190 days of follow-up support our assumption that this was a uniformly lowrisk cohort. Because of limitations of MarketScan, which does not capture data on mortality, we could not assess for death among our cohort. Given the age of the cohort and the low rate of MI, it is unlikely that cardiac death would have significantly contributed to differences in follow-up events.",[1],Medicine,test,1.0,news,http://www.sciencedaily.com/releases/2015/01/150126124608.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29 10.1093/sysbio/syq054,Medicine_easy_336,"Comparing DNA among related animals can provide a clear picture of how their shared genes evolved over time, giving rise to new and separate species, Martin said.",A few observations can be made from this figure.,"Evolutionary divergence of humans from chimpanzees likely occurred some 8 million years ago rather than the 5 million year estimate widely accepted by scientists, a new statistical model suggests. Comparing DNA among related animals can provide a clear picture of how their shared genes evolved over time, giving rise to new and separate species, Martin said. It can give scientists a broader perspective for interpreting data.","Also shown are the 95% CIs of the fossil calibrations for the crown primate and crown anthropoid nodes found from the fossil analysis (gray bars). A few observations can be made from this figure. First, there is broad agreement among all the point estimates and CIs for all the calibration models.",[1],Medicine,test,1.0,news,http://www.usnews.com/science/articles/2010/11/08/new-statistical-model-moves-human-evolution-back-3-million-years 10.1073/pnas.1617948114,Medicine_easy_346,"""So there's still a history in the soil that could be washed out during a flood year,"" Rabalais said.","Whether researchers can identify impacts from prices depends on the fisheries, the seafood markets, and data availability.","That could be because the farmers used more fertilizer last year -- or, because the rains were so frequent this winter and spring. ""So there's still a history in the soil that could be washed out during a flood year,"" Rabalais said. Why it matters We'll know the final verdict on this year's dead zone in late July, when marine scientists will cruise around the Gulf shore, capturing physical observations of the hypoxic zone.","Departures from stable price relationships could reveal impacts of an ecological disturbance on other fisheries. Whether researchers can identify impacts from prices depends on the fisheries, the seafood markets, and data availability. A substantial premium for soft and peeler crabs exists (the nominal 2014 Chesapeake Bay price for soft and peeler blue crabs was $3.63 per pound compared with $1.61 per pound for hard-shell crabs), but the markets are connected.",[1],Medicine,test,1.0,news,http://ct.moreover.com/?a=39439090562&p=1pl&v=1&x=UQyrvweU2ra3G62BAmaEDQ 10.1007/s11606-016-3760-9,Medicine_easy_354,"Credit: UT Southwestern People who visit their primary care physicians are more likely to get potentially life-saving colon cancer screenings and follow up on abnormal stool blood test results - even in health systems that heavily promote mail-in home stool blood tests that don't require a doctor visit, a study involving UT Southwestern population health researchers shows.",Almost one-third of patients had at least one comorbid condition.,"Credit: UT Southwestern People who visit their primary care physicians are more likely to get potentially life-saving colon cancer screenings and follow up on abnormal stool blood test results - even in health systems that heavily promote mail-in home stool blood tests that don't require a doctor visit, a study involving UT Southwestern population health researchers shows. The results are important because screening for colon cancer - the third most common cancer and the second leading cause of cancer deaths in the United States - is underutilized in the U.S. ""These findings help underscore the continued importance and effectiveness of visits with primary care physicians in a brave new world of virtual care and population health outreach,"" said Dr. Ethan Halm, Director of UT Southwestern's Center for Patient-Centered Outcomes Research, and a member of the Harold C. Simmons Comprehensive Cancer Center.","The population was racially and ethnically diverse, with 51.7 % non-Hispanic white, 19.0 % Hispanic, 12.3 % Asian, and 8.2 % black individuals. Almost one-third of patients had at least one comorbid condition. Sociodemographic characteristics of patients differed substantially among sites, based on differences in geography and socioeconomic status of the populations served.",[1],Medicine,test,1.0,news,http://healthmedicinet.com/news/primary-care-visits-result-in-more-colon-cancer-screening-better-followups/ 10.1098/rspb.2014.2335,Medicine_easy_358,"The study provides the first description of the dynamics of fungal infection and transmission in bats, and the findings are in striking contrast to most infectious diseases, said senior author Marm Kilpatrick, associate professor of ecology and evolutionary biology at UC Santa Cruz.","A yearly birth pulse may be important in driving transmission if either colony size or acquired immunity is important, and would result in sharp increases in prevalence in mid-summer after females have given birth .","But the remarkably high rate of infection during hibernation leads to high mortality rates at the time of year when bat populations are naturally at their lowest, before the females give birth in the summer. The study provides the first description of the dynamics of fungal infection and transmission in bats, and the findings are in striking contrast to most infectious diseases, said senior author Marm Kilpatrick, associate professor of ecology and evolutionary biology at UC Santa Cruz. ""In this case, transmission is tied to hibernation and body temperature.","If colony size is the primary mechanism driving transmission, we predict that prevalence would increase faster in seasons when colonies are larger. A yearly birth pulse may be important in driving transmission if either colony size or acquired immunity is important, and would result in sharp increases in prevalence in mid-summer after females have given birth . If contact with an environmental reservoir drives transmission, then prevalence would be predicted to increase significantly as bats contact infected environments.",[1],Medicine,test,1.0,news,http://www.sciencedaily.com/releases/2014/12/141203084101.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29 10.1007/s10142-018-0639-3,Medicine_easy_366,"""El desarrollo de indicadores espectrales relacionados con cambios fisiologicos detectables en estados iniciales -previsuales- de estres nos permite monitorizar espacial y temporalmente las interacciones entre respuesta genetica y las condiciones ambientales"", indica Pablo J. Zarco-Tejada, investigador vinculado al CSIC, profesor de la Universidad de Melbourne (Australia) y responsable de las metodologias de teledeteccion utilizadas.","The close physical proximity of the chromosome 5 and 6 DHN genes, together with the phylogenetic analysis, suggests that these clusters arose through multiple rounds of duplications.","Estos avances en el conocimiento de los genes del trigo que responden a las variaciones en las condiciones ambientales permiten un nuevo enfoque para afinar los procesos de mejora y obtencion de nuevas variedades, y conseguir que en el futuro estan mejor equipadas geneticamente para hacer frente a cambios en las condiciones agroclimaticas. ""El desarrollo de indicadores espectrales relacionados con cambios fisiologicos detectables en estados iniciales -previsuales- de estres nos permite monitorizar espacial y temporalmente las interacciones entre respuesta genetica y las condiciones ambientales"", indica Pablo J. Zarco-Tejada, investigador vinculado al CSIC, profesor de la Universidad de Melbourne (Australia) y responsable de las metodologias de teledeteccion utilizadas. En concreto, los sensores hiperespectrales utilizados permiten la cuantificacion de la emision de fluorescencia clorofilica de cada parcela experimental, indicador directamente relacionado con la fotosintesis, asi como la caracterizacion de xantofilas, unos pigmentos fotosinteticos clave por su conexion con la eficiencia fotosintetica en situaciones de estres.","5a ) corresponded to CoDReG_6_581_01, which is in the same physical position as previously defined wheat drought Meta-QTLs on chromosomes 6B and 6D (MQTL53 and MQTL56 identification of this region across independent studies highlights its potential as a breeding target. The close physical proximity of the chromosome 5 and 6 DHN genes, together with the phylogenetic analysis, suggests that these clusters arose through multiple rounds of duplications. This is reminiscent of other major stress tolerance loci, such as the CBF cluster associated with cold tolerance in wheat.",[1],Medicine,test,1.0,news,http://ct.moreover.com/?a=38661668947&p=1pl&v=1&x=hHjbofo7g0MdGh1zsuzYkw 10.1038/sj.jhh.1001147,Medicine_easy_370,This isn't how it should be done naturally.,Analysis of home-measured data showed an average BP change of ؊5.0/؊2.7 mm Hg in the active treatment group and ؊1.2/؉0.9 mm Hg in the control group.,"Well, apparently if you breathe correctly you might be in for a massive surprise. This isn't how it should be done naturally. You must avoid any breathwork that activates the sympathetic nervous system while congested.","The BP change at the clinic was ؊7.5/؊4.0 mm Hg in the active treatment group, vs ؊2.9/؊1.5 mm Hg in the control group (P ‫؍‬ 0.001 for systolic BP). Analysis of home-measured data showed an average BP change of ؊5.0/؊2.7 mm Hg in the active treatment group and ؊1.2/؉0.9 mm Hg in the control group. Ten out of 18 (56%) were defined as responders in the active treatment group but only two out of (%) in the control group (P ‫؍‬ 0.02).",[1],Medicine,test,1.0,news,http://ct.moreover.com/?a=39600522308&p=1pl&v=1&x=sAOvjSCiiP_glF_cau_LaQ 10.1073/pnas.1508431112,Medicine_easy_377,"Only musicians, however, showed oscillations that synchronized with unusually slow clips.",6B shows a similar analysis (comparing hits against misses) in channel space.,"For music that is faster than one note per second, both musicians and non-musicians showed cortical oscillations that synchronized with the note rate of the clips--in other words, these oscillations were effectively employed by everyone to process the sounds they heard, although musicians' brains synchronized more to the musical rhythms. Only musicians, however, showed oscillations that synchronized with unusually slow clips. This difference, the researchers say, may suggest that non-musicians are unable to process the music as a continuous melody rather than as individual notes.",Multiple comparisons are corrected for using FDR at the 0.05 level. 6B shows a similar analysis (comparing hits against misses) in channel space. These channels are more central than those of the auditory localizer (Fig.,[1],Medicine,test,1.0,news,http://www.futurity.org/musicians-brains-rhythms-1034492-2/ 10.1001/jamapsychiatry.2014.724,Medicine_easy_400,"Women with a history of military service in both eras had similar patterns of elevated odds for physical abuse, household alcohol abuse, exposure to domestic violence and emotional abuse compared with women who had not been in the military.","After adjusting for demographic information, women with a history of military service in both eras had similar patterns of elevated odds for physical abuse, household alcohol abuse, exposure to domestic violence, and emo-","Fewer differences in ACEs were found among women with and without military service than among men. Women with a history of military service in both eras had similar patterns of elevated odds for physical abuse, household alcohol abuse, exposure to domestic violence and emotional abuse compared with women who had not been in the military. Women who served in the military during the all-volunteer era also were more likely to report being touched sexually.","Fewer differences were noted among women from the draft era, with larger proportions of women with a history of military service reporting physical abuse, exposure to domestic violence, and emotional abuse than women without a history of military service. After adjusting for demographic information, women with a history of military service in both eras had similar patterns of elevated odds for physical abuse, household alcohol abuse, exposure to domestic violence, and emo- As the largest US study, to our knowledge, to examine the prevalence of ACEs among men and women by history of military service, our study found an elevated prevalence of ACEs among men and women who have served in the military.",[5],Medicine,test,5.0,news,http://www.sciencedaily.com/releases/2014/07/140723162044.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29 10.1016/j.annemergmed.2018.04.007,Medicine_easy_443,"Specifically, patients who receive opioid agonist therapy as part of treatment for opioid use disorder have a decreased chance of fatal overdose compared with those who receive psychological counseling alone.","Specifically, patients who receive opioid agonist therapy as part of treatment for opioid use disorder have a decreased chance of fatal overdose compared with those who receive psychological counseling alone.","MAT improves long-term outcomes for patients, the authors note. Specifically, patients who receive opioid agonist therapy as part of treatment for opioid use disorder have a decreased chance of fatal overdose compared with those who receive psychological counseling alone. Patients maintained on buprenorphine have fewer emergency visits and hospitalizations.","46 When buprenorphine is used as medication-assisted therapy, follow-up care can be obtained through opioid treatment programs, hospitals, health departments, and other qualified providers, as detailed below. Specifically, patients who receive opioid agonist therapy as part of treatment for opioid use disorder have a decreased chance of fatal overdose compared with those who receive psychological counseling alone. Furthermore, patients receiving maintenance buprenorphine for at least a year require fewer ED visits and hospitalizations compared with those who discontinue buprenorphine.",[5],Medicine,test,5.0,news,http://ct.moreover.com/?a=34305589338&p=1pl&v=1&x=pmOHxI66K9n3YdPys_UENg 10.1136/jnnp-2012-303826,Medicine_easy_460,"""We are aware of the many ethical and sociopolitical considerations related to psychosurgery, but we think that such surgery is appropriate under thoughtful regulation, particularly when the disorder is chronic, intractable to non-invasive treatment modalities and when surgery is the last therapeutic option.""","We are aware of the many ethical and sociopolitical considerations related to psychosurgery, but we think that such surgery is appropriate under thoughtful regulation, particularly when the disorder is chronic, intractable to non-invasive treatment modalities and when surgery is the last therapeutic option.","Moreover, the effectiveness of the brain surgeries matched similar studies conducted on psychosurgeries for OCD. ""We are aware of the many ethical and sociopolitical considerations related to psychosurgery, but we think that such surgery is appropriate under thoughtful regulation, particularly when the disorder is chronic, intractable to non-invasive treatment modalities and when surgery is the last therapeutic option."" The researchers called for more studies, on a larger scale, to determine reliable means of predicting outcomes to treatment, which would allow doctors and patients more information when considering this last-resort option.","The efficacy of this surgery was maintained for many years (mean of 7 years), with no newly acquired side effects. We are aware of the many ethical and sociopolitical considerations related to psychosurgery, but we think that such surgery is appropriate under thoughtful regulation, particularly when the disorder is chronic, intractable to non-invasive treatment modalities and when surgery is the last therapeutic option. Moreover, large-scale controlled studies are needed to identify reliable predictors of treatment response and then optimise the risk/benefit ratio of this surgery.",[5],Medicine,test,5.0,news,http://www.medicaldaily.com/articles/16124/20130603/ocd-obsessive-compulsive-disorder-surgery-psychiatry.htm 10.1001/jama.2014.7587,Medicine_easy_462,"The researchers add that although a thorough cost analysis was beyond the scope of this study, the significantly shorter length of hospital stay and fewer common duct investigations in the study group, coupled with the similar complication rates between the 2 groups, predicts substantial savings when using a cholecystectomy-first strategy.","Although a thorough cost analysis was beyond the scope of the present study, the significantly shorter length of hospital stay and fewer common duct investigations in the study group, coupled with the similar complication rates between the 2 groups, predicts substantial savings when using a cholecystectomy-first strategy.","The authors note that overall, 60 percent of patients in the study group did not need any common duct investigation after the intraoperative cholangiogram. The researchers add that although a thorough cost analysis was beyond the scope of this study, the significantly shorter length of hospital stay and fewer common duct investigations in the study group, coupled with the similar complication rates between the 2 groups, predicts substantial savings when using a cholecystectomy-first strategy. ""If these findings are confirmed, initial cholecystectomy with intraoperative cholangiogram may be a preferred approach,"" the authors conclude.","Of note, 1-and 6-month follow-ups showed excellent quality of life and no statistically significant difference between groups. Although a thorough cost analysis was beyond the scope of the present study, the significantly shorter length of hospital stay and fewer common duct investigations in the study group, coupled with the similar complication rates between the 2 groups, predicts substantial savings when using a cholecystectomy-first strategy. Both result in similar outcomes.",[5],Medicine,test,5.0,news,http://www.sciencedaily.com/releases/2014/07/140708165723.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29 10.1111/jgs.14826,Medicine_easy_463,"In 2013, Medicare spent an estimated $15 billion on hospice, representing a 420 percent growth over the past 13 years.","10 In 2013, Medicare spent an estimated $15 billion on hospice, representing 420% growth over the past 13 years.","Expenditures for hospice care have significantly increased as use of the benefit has increased. In 2013, Medicare spent an estimated $15 billion on hospice, representing a 420 percent growth over the past 13 years. Assisted Living Facility vs. Home"" is published online ahead of print in the Journal of the American Geriatrics Society.","Indeed, hospice care is associated with higher quality end-of-life care, including less burdensome treatments near the end of life and higher family satisfaction. 10 In 2013, Medicare spent an estimated $15 billion on hospice, representing 420% growth over the past 13 years. 11 Further hospice payment reforms are being considered, including changes to payments based on site of care.",[5],Medicine,test,5.0,news,http://healthmedicinet.com/news/study-compares-hospice-care-in-nursing-homes-assisted-living-facilities-and-patient-homes/ 10.1001/jamapediatrics.2017.4083,Medicine_easy_477,"""Results suggest that the KFRE could be incorporated into the clinical care of children with CKD to aid in anticipatory guidance, timing of referral for transplant evaluation, and planning for dialysis access,"" the authors write.","Results suggest that the KFRE could be incorporated into the clinical care of children with CKD to aid in anticipatory guidance, timing of referral for transplant evaluation, and planning for dialysis access.","The researchers found that over a median observation time of 3.8 years, 144 participants (23.9 percent) developed ESRD within five years of enrollment. The predictive abilities of the four- and eight-variable KFRE scores were similar for discrimination of ESRD risk (C statistics of 0.90, 0.86, and 0.81 for the one-, two-, and five-year four-variable KFRE risk scores, respectively; 0.91, 0.87, and 0.82, respectively, for the eight-variable KFRE scores). ""Results suggest that the KFRE could be incorporated into the clinical care of children with CKD to aid in anticipatory guidance, timing of referral for transplant evaluation, and planning for dialysis access,"" the authors write.","CONCLUSIONS AND RELEVANCE The KFRE is a simple tool that provides excellent discrimination of the risk of ESRD. Results suggest that the KFRE could be incorporated into the clinical care of children with CKD to aid in anticipatory guidance, timing of referral for transplant evaluation, and planning for dialysis access. Improved estimation of when a child with CKD will experience progression to ESRD has several potentially valuable applications.",[5],Medicine,test,5.0,news,http://ct.moreover.com/?a=32814760646&p=1pl&v=1&x=s7LNbnMajjBSjhxJ1Wbz8Q 10.1038/s41598-018-34535-z,Medicine_easy_479,"""Based on our measurements on the guinea-pig heart, we conclude that real-time detection of the heartbeat of a human fetus at gestational age of 18-22 weeks, where the heart-sensor distance is estimated to be >= 5 cm, should be possible,"" say Jensen and co.","Based on our measurements on the guinea-pig heart, we conclude that real-time detection of the heartbeat of a human fetus at gestational age of 18-22 weeks, where the heart-sensor distance is estimated to be ≥ 5 cm, should be possible.","The new technique should be able to do just that. ""Based on our measurements on the guinea-pig heart, we conclude that real-time detection of the heartbeat of a human fetus at gestational age of 18-22 weeks, where the heart-sensor distance is estimated to be >= 5 cm, should be possible,"" say Jensen and co. This sets up an exciting future.","Such an improved sensitivity would also allow for real-time recordings of MCGs at larger distances. Based on our measurements on the guinea-pig heart, we conclude that real-time detection of the heartbeat of a human fetus at gestational age of 18-22 weeks, where the heart-sensor distance is estimated to be ≥ 5 cm, should be possible. We also note, that our OPM works at physiological temperatures, which would allow for probes designed for use inside the human body.",[5],Medicine,test,5.0,news,http://ct.moreover.com/?a=34512795142&p=1pl&v=1&x=fVtt4-NDZDjEm_lnyBfICA 10.1177/0141076813486779,Medicine_easy_482,They concluded that population-based mortality statistics for England do not show a past benefit of breast cancer screening.,"We conclude that population-based mortality statistics, at least in England, do not show a past benefit of breast cancer screening.","They concluded that population-based mortality statistics for England do not show a past benefit of breast cancer screening. The new research contrasts with the findings of an independent review commissioned by the Department of Health published in 2012 which concluded that there was a 20% relative reduction in mortality from breast cancer in women invited to screening. The review also found that for each breast cancer death prevented, about three over-diagnosed cases will be identified and treated.","In older age groups, a smaller percentage of breast cancer deaths are coded as the underlying cause (for example, 78% in women aged 75-84 years), and figures on breast cancer mortality based on underlying cause alone should be treated with greater caution. We conclude that population-based mortality statistics, at least in England, do not show a past benefit of breast cancer screening. While this does not rule out a benefit at the level of individual women, these effects are not large enough to be detected at the population-level.",[5],Medicine,test,5.0,news,http://www.sciencedaily.com/releases/2013/06/130611102159.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29 10.1073/pnas.1703516114,Medicine_easy_490,The entanglement is a peculiar correlation that exists only in quantum mechanics and is at the very foundation of the possible functioning of quantum computers.,"First, in the stationary state the density of thermodynamic entropy coincides with that of the entanglement entropy in (2), as it has been shown analytically for free models .","In particular, the authors have shown that if in an extended quantum system far from equilibrium we look at just one part thereof, this has an entropy that increases in time, exactly like in thermodynamics. The origin of this entropy is in the entanglement between the part we are looking at and the rest of the system. The entanglement is a peculiar correlation that exists only in quantum mechanics and is at the very foundation of the possible functioning of quantum computers.","Physically, this reflects a generalized microcanonical ensemble for quenches, in which all the microstates corresponding to the macrostate have the same probability. First, in the stationary state the density of thermodynamic entropy coincides with that of the entanglement entropy in (2), as it has been shown analytically for free models . This implies that",[1],Medicine,test,1.0,news,http://www.spacedaily.com/reports/The_role_of_the_entropy_in_a_quantum_system_999.html 10.1038/s41467-017-01285-x,Medicine_easy_494,"""Their separation was caused by the ascent of a 'mantle plume' from the deep mantle, which broke the much thinner and more fragile crust and caused the separation of the two continents.",The chosen acquisition setup represents a typical scenario for an applied tractography study and embodies a common denominator supported by the large majority of methods.,"Inside such material, the researchers discovered tiny traces of gold, the deepest ever found beneath the South American continent. ""Their separation was caused by the ascent of a 'mantle plume' from the deep mantle, which broke the much thinner and more fragile crust and caused the separation of the two continents. ""The ascent of the deep mantle plume generated a true chemical factory that enriched the mantle with metals, which would later generate the conditions for the creation of gold deposits.","7 illustrates the result of this refining procedure on the left CST. The chosen acquisition setup represents a typical scenario for an applied tractography study and embodies a common denominator supported by the large majority of methods. Since acquisitions with higher b-values, more gradient directions and fewer artifacts are beneficial for tractography, we additionally report a least upper bound tractography performance under perfect image quality conditions using a data set that directly contains ground truth fiber orientation information at high spatial resolution with no artifacts (Fig.",[1],Medicine,test,1.0,news,http://ct.moreover.com/?a=32607241264&p=1pl&v=1&x=-Nw0mLr2mLFn9Zs1_OiAEA 10.1038/s41556-018-0140-1,Medicine_easy_496,"They found that resistance to PARP inhibitors cause some cancer cells to develop vulnerabilities to alternative cancer treatments, including radiotherapy or platinum-based chemotherapy.",4a ) 33 .,"But when Shieldin levels are low, patients can develop resistance to these drugs."" Mice had low levels of Shieldin originally and didn't respond to the PARP inhibitors. They found that resistance to PARP inhibitors cause some cancer cells to develop vulnerabilities to alternative cancer treatments, including radiotherapy or platinum-based chemotherapy.","TRF2ts inactivation at higher temperatures results in deprotected chromosome ends and causes NHEJ-mediated telomere fusions ( Fig. 4a ) 33 . Strikingly, through the use of short-hairpin RNA (shRNA) mediated mRNA silencing, we found that such chromosome fusions were diminished by FAM35A or C20orf196 depletion, like that elicited by MAD2L2 depletion ( Fig.",[1],Medicine,test,1.0,news,http://ct.moreover.com/?a=34632630863&p=1pl&v=1&x=jGYZgnCY8FeDZnqhsmy1rQ 10.1002/pam.22030,Medicine_easy_506,"Based on our research, we expect that a sincere and honest attempt to enact paid family leave will likely draw wide support.","This latter specification should be expected to attenuate the results slightly, as a smaller fraction of the treated sample is eligible for leave.","Interestingly, in both states there were no significant differences across firms of different sizes, nor between firms with different proportions of part-time or female employees. That number will go up in 2020 when Washington state and Washington, D.C., implement programs as well. Based on our research, we expect that a sincere and honest attempt to enact paid family leave will likely draw wide support.","46 Specifically, the results in Table 2 hold if all fathers who have worked any positive number of weeks in the previous 12 months are included in the sample, or if all fathers with age-eligible children are included in the sample, regardless of employment status. This latter specification should be expected to attenuate the results slightly, as a smaller fraction of the treated sample is eligible for leave. However, given the high employment rate among fathers, the samples do not change dramatically, and estimated CA-PFL effects remain substantial, although slightly smaller on average than previously.",[1],Medicine,test,1.0,news,http://ct.moreover.com/?a=34325726330&p=1pl&v=1&x=G8yUaMs63u-659f67hEU6g 10.1016/j.neuron.2013.03.006,Medicine_easy_512,It sounds like a strong wind.,Latency of these components did not differ between inphase and out-of-phase stimulation (p > 0.347).,"Brown noise generally has fewer higher frequencies than white or pink noise, and tends to sound rougher, Breus says. It sounds like a strong wind. But there may be a good reason to choose pink.","Amplitude of the late negative component was slightly smaller for the out-of-phase than in-phase stimulation (p = 0.019 for comparison at Cz), which probably reflects reduced neocortical excitability when the stimulus is presented during the SO down state . Latency of these components did not differ between inphase and out-of-phase stimulation (p > 0.347). Our data indicate that an enhancement of SO activity and overnight memory consolidation by auditory stimulation depends essentially on a timing in phase with SO up states.",[1],Medicine,test,1.0,news,http://ct.moreover.com/?a=38645934720&p=1pl&v=1&x=hA1UNSZvyy-kGvPW5xwaZg 10.1038/s41467-018-06789-8,Medicine_easy_514,But it wasn't quite that simple.,"We observed bleaching of the non-oxidized samples, while oxidized nanoparticles did not bleach over tens of minutes of measurements.","(Image: IOCB Prague) A pure nanodiamond, though, doesn't reveal much about its environment. But it wasn't quite that simple. The high density of this particle shower and the use of a reactor to irradiate a much larger quantity of material mean that it is easier and far more affordable to produce dozens of grams of rare nanomaterial at once, which is approximately one thousand times more than scientists have thus far been able to obtain through comparable irradiation in accelerators.","Oxidation further improved the solubility of both irradiated and non-irradiated samples and led to stabilization of luminescence. We observed bleaching of the non-oxidized samples, while oxidized nanoparticles did not bleach over tens of minutes of measurements. Overall, our data point towards effective creation of photoluminescent point defects in cubic SiC nanoparticles and demonstrate the capability of our irradiation method for nanomaterials other than NDs.",[1],Medicine,test,1.0,news,http://ct.moreover.com/?a=37642670147&p=1pl&v=1&x=4VpoeKXALd6UTWn9fxoFsw 10.1021/acsami.8b09899,Medicine_easy_517,We believe this new understanding of roughness across scales will open the door to finally solving this age-old puzzle in surface analysis.,"Since we do not know the value of the slope ! ""","We can calculate true scale-invariant roughness parameters. We believe this new understanding of roughness across scales will open the door to finally solving this age-old puzzle in surface analysis. Dr. Jacobs breakthrough is the first step in an uphill, and very steep, battle to create and validate these models.","# , 0 . Since we do not know the value of the slope ! "" By assuming that the distribution of slopes in x-and ydirection is independent (which is true for a Gaussian distribution of slopes), we can express ! """,[1],Medicine,test,1.0,news,http://ct.moreover.com/?a=37842390940&p=1pl&v=1&x=mDOP2rqsqJtXLF4eTVfNdw 10.1007/s00125-015-3518-7,Medicine_easy_520,"""One of the advantages of DPP-4 inhibition as a treatment for diabetes is the very low risk of hypoglycaemia.",[ Fig.,"Diabetes drug could protect against low blood sugar ""If these inhibitors also prove effective in humans against low blood sugar, then this supports the idea that the area of application of these drugs could be broadened to include persons with diabetes that is difficult to control and suffer from frequent hypoglycaemias"", said Siri Malmgren, a researcher at Lund University. ""One of the advantages of DPP-4 inhibition as a treatment for diabetes is the very low risk of hypoglycaemia. Through Dr Malmgren's important work, a fundamental new principle for this has been identified.",It was found that GIR was lowered by 89.0± 3.1% in mice given vildagliptin compared with control mice (3.9 ± 1.1 vs 35.1 ± 3.1 μmol kg [ Fig. 1c] ).,[1],Medicine,test,1.0,news,http://www.healthcanal.com/metabolic-problems/diabetes/60455-diabetes-drug-could-protect-against-low-blood-sugar.html 10.1126/science.aap7999,Medicine_easy_524,"It show that there are many forms of Bd and that the fungus can mutate quickly, changing from a mild version into a deadly version almost overnight.","Combining molecular modeling, combinatorial chemistry, and high-throughput screening has the potential to develop chemicals with reduced resistance risk (37) .","Unfortunately, this research is simply bad news for those amphibian populations. It show that there are many forms of Bd and that the fungus can mutate quickly, changing from a mild version into a deadly version almost overnight. Short of developing some sort of cure and delivering it to populations of amphibians, it may simply be up to those amphibians to survive by themselves.","This situation parallels the situation for antibiotics. Combining molecular modeling, combinatorial chemistry, and high-throughput screening has the potential to develop chemicals with reduced resistance risk (37) . Where target-site mutations confer high levels of resistance, lower doses of antifungals should be favored (40, 41) .",[1],Medicine,test,1.0,news,http://ct.moreover.com/?a=34034138827&p=1pl&v=1&x=IHpVkTvYlwD40MBxQOfGXQ 10.1126/scitranslmed.aao3089,Medicine_easy_526,"Da qui deriva il suo nome che in greco significa appunto ""pelle dura"".",NET generation was reduced in the presence of BoxA (Fig.,"Cos'e la sclerodermia La sclerodermia, che colpisce soprattutto le donne tra i 30 e i 50 anni, e una malattia rara di origine autoimmune che porta all'accumulo di tessuto fibroso sulla pelle e sugli organi interni. Da qui deriva il suo nome che in greco significa appunto ""pelle dura"". A seconda degli organi che colpisce, questo ispessimento - chiamato fibrosi - puo dare origine a complicanze anche gravi, come nel caso dei polmoni.","Control-microparticles did not induce detectable NET generation. NET generation was reduced in the presence of BoxA (Fig. 2C) ; conversely, adherent neutrophils challenged with recombinant human HMGB1 and released NETs (Fig.",[1],Medicine,test,1.0,news,http://ct.moreover.com/?a=34639622685&p=1pl&v=1&x=1aR4inwkdVwA-_KXDxmmhA 10.1016/j.cell.2014.01.008,Medicine_easy_531,Researchers and health officials hope that these papers will eventually help rein in the overwhelming epidemic that currently affects more than one-third of U.S. adults.,the period(s) of hypothalamic neurocircuit development most strongly perturbed by maternal HFD feeding to impair energy and glucose homeostasis in the offspring.,"Obesity during Pregnancy The current study is the latest in growing series of efforts to illuminate the potential consequences of obesity during pregnancy. Researchers and health officials hope that these papers will eventually help rein in the overwhelming epidemic that currently affects more than one-third of U.S. adults. By pinpointing a critical moment in the child's metabolic programming, the results reveal a developmental stage where proper nutrition is more important than ever.","*p < 0.05, **p < 0.01, and ***p < 0.001 versus all other groups of offspring unless otherwise indicated. the period(s) of hypothalamic neurocircuit development most strongly perturbed by maternal HFD feeding to impair energy and glucose homeostasis in the offspring. Our study not only shows that the lactation period in rodents is most sensitive to the altered developmental environment in response to maternal HFD feeding, predisposing the offspring for metabolic diseases as described before ), but importantly demonstrates that the short exposure to HFD during this distinct developmental phase is sufficient to predispose the offspring for metabolic disorders, at least in part via impairing ARH neuronal innervation of intrahypothalamic target areas.",[1],Medicine,test,1.0,news,http://www.medicaldaily.com/obesity-during-pregnancy-rewires-childs-brain-increases-risk-metabolic-disorders-diabetes-267737 10.1016/j.vaccine.2017.05.050,Medicine_easy_536,"However, not everyone shows the same antibody responses to the vaccine.",1; Table 3 ).,"However, not everyone shows the same antibody responses to the vaccine. The results, published in Vaccine, found that women who hadn't received a flu shot in the previous year had better initial immune responses to the vaccine. For those who had received a flu shot the previous year, their peak antibody responses were weakened.","At baseline, women vaccinated the previous year had greater odds of having a higher HAI titer for A/H1N1 (p = 0.001), A/H3N2 (p = 0.04), and B/Massachusetts (p = 0.01), with a similar but non-significant trend for B/Brisbane (p = 0.12) compared to women not vaccinated the previous year ( Fig. 1; Table 3 ). Per logistic regression utilizing the same covariates, women with prior vaccination had higher seroprotection rates (i.e., titer",[1],Medicine,test,1.0,news,http://healthmedicinet.com/news/study-charts-flu-shots-impact-on-pregnant-women-and-their-babies/ 10.1038/s41559-018-0766-1,Medicine_easy_556,"""To be clear, our study does not suggest that having a particular combination of mitochondrial and nuclear genes would provide an advantage or a disadvantage,"" says Makova.",5) .,"In the future, they plan to investigate this question and also to explore the effects of discordance on other aspects of mitochondrial function and on other complex traits such as the rate of heart disease. ""To be clear, our study does not suggest that having a particular combination of mitochondrial and nuclear genes would provide an advantage or a disadvantage,"" says Makova. ""But it does tell us that we should keep investigating these differences in geographic origin between these two groups of genes.","We found a significant enrichment in Native American ancestry at high-mt genes in Puerto Ricans, and a significant enrichment in African ancestry at high-mt genes in African Americans (Fig. 5) . Because Native American mtDNA haplogroups are more frequent in Puerto Ricans and African mtDNA haplogroups are more frequent in African Americans (Fig.",[1],Medicine,test,1.0,news,https://www.futurity.org/mitochondria-genes-geography-1956072-2/ 10.1242/jeb.093658,Medicine_easy_565,"""This research is the perfect example of how a fortuitous discovery can redefine our understanding of the world around us,"" said van Doorn.",there was no constriction or emptying of the blood vessels.,"Together, these experiments show the relationship between environmental stimuli and vision, as well as highlight the interesting and complex effect blood flow patterns have on visual clarity. Future research will investigate the mechanism underlying this relationship. ""This research is the perfect example of how a fortuitous discovery can redefine our understanding of the world around us,"" said van Doorn.","During the renewal phase of the integument, spectacle blood flow was found to remain constant when the snakes were undisturbedi.e. there was no constriction or emptying of the blood vessels. When the snakes were handled or otherwise disturbed, blood flow would slow or stop for brief periods of the order of 1-10s, but the spectacle blood vessels remained fully dilated and did not empty.",[1],Medicine,test,1.0,news,http://www.sciencedaily.com/releases/2013/11/131104142424.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29 10.1038/s41467-018-07785-8,Medicine_easy_581,Pitt also noted that similar mechanisms might apply to other autoimmune diseases such as rheumatoid arthritis and Type 1 diabetes.,We found that the risk variant was not associated with a significant increase in lesion load in patients (Supplementary Fig.,"""This understanding increases the number of possible targets available for treatment moving forward."" Pitt also noted that similar mechanisms might apply to other autoimmune diseases such as rheumatoid arthritis and Type 1 diabetes.",9 ). We found that the risk variant was not associated with a significant increase in lesion load in patients (Supplementary Fig. 10 ).,[1],Medicine,test,1.0,news,http://ct.moreover.com/?a=38008356154&p=1pl&v=1&x=K9y1bC3P6A62Zi4tURR0Pg 10.1038/s41564-018-0291-7,Medicine_easy_603,"""Our results indicate that those parasites activating the expression of PfAP2-G early enough during the cycle can take the rapid route, whereas the others need to go through a replication cycle before converting into gametocytes,"" explains first author Cristina Bancells.",(Fig.,"""The point at which the parasite decides to become a gametocyte turned out to be earlier than previously thought,"" explains Cortes. ""Our results indicate that those parasites activating the expression of PfAP2-G early enough during the cycle can take the rapid route, whereas the others need to go through a replication cycle before converting into gametocytes,"" explains first author Cristina Bancells. ""This rapid route could favor the parasite's survival and transmission in a 'dangerous' situation, for example in the case of drug treatment,"" she adds.","and decreased until 30-35 h.p.i. (Fig. In addition to late schizonts, 40-45 h.p.i.",[1],Medicine,test,1.0,news,http://ct.moreover.com/?a=37805062589&p=1pl&v=1&x=BsI7ULGK_6qRes58lb7smw 10.1038/nature13898,Medicine_easy_604,"""We hope that we're at the beginning of a reawakening interest in the environment as an inducer of cancer,"" Balmain said.","These patterns confirm previous results on carcinogen-specific mutations in Kras 6,9,10 .","The results are also consistent with observations that tumors arising in human organs that are most directly exposed to environmental carcinogens--the skin, gastrointestinal system, and lungs--are more prone to point mutations than more ""protected"" organs such as the brain, breast, and prostate gland. But only a very small number of the 25 mutational signatures revealed by NGS in human tumors so far have been convincingly tied to environmental exposures, Balmain said, so there is much to learn. ""We hope that we're at the beginning of a reawakening interest in the environment as an inducer of cancer,"" Balmain said.","The vast majority of Kras mutations were validated by Sanger sequencing, although a small subset went undetected by this method ( Supplementary Table 1 ) despite confirmation by manual inspection of the alignments, suggesting a higher sensitivity afforded by WES. These patterns confirm previous results on carcinogen-specific mutations in Kras 6,9,10 . A transitions in driver genes in the adenocarcinoma samples, 15 of which passed ( Supplementary Table 8 ).",[1],Medicine,test,1.0,news,http://www.healthcanal.com/cancers/57039-environmental-carcinogens-leave-distinctive-genetic-imprints-in-tumors.html 10.1098/rsbl.2018.0484,Biology_0,"Close Researchers find a reduction in the complexity of dolphin whistles as a result of increased ship noise.","Increases in ship noise, both within and below the dolphins' call bandwidth, resulted in higher dolphin whistle frequencies and a reduction in whistle contour complexity, an acoustic feature associated with individual identification.","Close Researchers find a reduction in the complexity of dolphin whistles as a result of increased ship noise. What they found was that the increases in vessel noises resulted in higher whistle frequencies with reductions in complexity. In other words, the dolphins whistled more, but with much less complexity.","Elevated ambient noise levels were mainly caused by ship noise. Increases in ship noise, both within and below the dolphins' call bandwidth, resulted in higher dolphin whistle frequencies and a reduction in whistle contour complexity, an acoustic feature associated with individual identification. Consequently, the noiseinduced simplification of dolphin whistles may reduce the information content in these acoustic signals and decrease effective communication, parent -offspring proximity or group cohesion.","[2.0, 4.0, 3.0, 5.0, 4.0]",Biology,test,3.6,news,http://ct.moreover.com/?a=37527595797&p=1pl&v=1&x=I3-Y0zFdrh-3KNec4pO_bg 10.1098/rsbl.2018.0484,Biology_107,"""Dolphins simplified their calls to counter the masking effects of vessel noise.""","If a vessel is located in a different direction from conspecifics, there may be a decrease in masking (spatial release from masking) , but the observed changes in the whistle signals indicate that the dolphins simplified their calls to counter the masking effects of vessel noise.","'The Shortest Answer Possible' Communication Is very important for dolphins, and they rely on sounds to do so. This not just makes it difficult for them to communicate, but it masks their individual identification, and might also reduce the information in their whistles. ""Dolphins simplified their calls to counter the masking effects of vessel noise.""","The study area is adjacent to the shipping lanes into Delaware Bay (electronic supplementary material, figure S1 ) and had ambient noise levels comparable to other coastal areas with frequent vessel traffic . If a vessel is located in a different direction from conspecifics, there may be a decrease in masking (spatial release from masking) , but the observed changes in the whistle signals indicate that the dolphins simplified their calls to counter the masking effects of vessel noise. Ambient noise levels are likely to rise in the future as vessel traffic increases and an offshore wind energy facility is proposed.","[4.0, 4.0, 4.0, 5.0, 3.0]",Biology,test,4.0,news,http://ct.moreover.com/?a=37527595797&p=1pl&v=1&x=I3-Y0zFdrh-3KNec4pO_bg 10.1210/en.2013-1955,Biology_114,"""Our research provides the first direct evidence that exposure to BPA during development, at the levels we see in our day-to-day lives, increases the risk for prostate cancer in human prostate tissue,"" Prins said.",Examples of HG-PIN and prostate adenocarcinoma as well as benign lesions of hyperplasia and SQM are shown in Fig 5 with PSA immunostaining to confirm their human origin and lack of basal cell staining to confirm carcinoma.,"This is a major concern as the chemical imitated the hormone estrogen. ""Our research provides the first direct evidence that exposure to BPA during development, at the levels we see in our day-to-day lives, increases the risk for prostate cancer in human prostate tissue,"" Prins said. ""The findings of adverse effects of BPA in human tissue are highly relevant and should encourage agencies like the Food & Drug Administration to re-evaluate their policies in the near future.""","As previously observed (28), progressive malignancy incidence was noted over time with highest HG-PIN and cancer incidence present at 4 months. Examples of HG-PIN and prostate adenocarcinoma as well as benign lesions of hyperplasia and SQM are shown in Fig 5 with PSA immunostaining to confirm their human origin and lack of basal cell staining to confirm carcinoma. As shown in Table 1 , prostate grafts from animals treated with vehicle during tissue development plus T+E exposure at maturity had an overall incidence of 26% normal grafts, 74% benign lesions and 13% malignant lesions (Note: malignant lesions always co-appeared in grafts containing 16 benign lesions).","[2.0, 1.0, 2.0, 2.0, 2.0]",Biology,test,1.8,news,http://www.scienceworldreport.com/articles/12081/20140110/fetal-exposure-to-chemicals-in-plastic-bottles-increases-risk-of-prostate-cancer-later-study-confirms.htm 10.1210/en.2013-1955,Biology_134,"""Our research provides the first direct evidence that exposure to BPA during development, at the levels we see in our day-to-day lives, increases the risk for prostate cancer in human prostate tissue,"" Prins said.","Although genomic actions of BPA through EREs could not be confirmed in the present study, this activity has not been excluded as it remains possible that BPA may activate genomic ER signaling on natural promoters or over a different time frame than examined herein.","The new findings show that human prostate tissue is also susceptible. ""Our research provides the first direct evidence that exposure to BPA during development, at the levels we see in our day-to-day lives, increases the risk for prostate cancer in human prostate tissue,"" Prins said. ""The findings of adverse effects of BPA in human tissue are highly relevant and should encourage agencies like the Food & Drug Administration to re-evaluate their policies in the near future.""","BPA at doses up to 1 M did not elicit an ERE-based responses with the ERE-tk reporter (Fig 3C) . Although genomic actions of BPA through EREs could not be confirmed in the present study, this activity has not been excluded as it remains possible that BPA may activate genomic ER signaling on natural promoters or over a different time frame than examined herein. Taken together, these findings identify that both rapid membrane-initiated estrogen action and genomic ER signaling pathways are operative in human prostate progenitor cells.","[2.0, 1.0, 2.0]",Biology,test,1.6666666666666667,news,http://www.healthcanal.com/cancers/46375-bpa-increases-risk-of-cancer-in-human-prostate-tissue.html 10.1093/sysbio/syq054,Biology_153,"Evolutionary divergence of humans from chimpanzees likely occurred some 8 million years ago rather than the 5 million year estimate widely accepted by scientists, a new statistical model suggests.","Compared with two recent molecular studies of primate divergence dates Young 2006, 2008) , the majority of our estimates are somewhat older (Fig.","Evolutionary divergence of humans from chimpanzees likely occurred some 8 million years ago rather than the 5 million year estimate widely accepted by scientists, a new statistical model suggests. Comparing DNA among related animals can provide a clear picture of how their shared genes evolved over time, giving rise to new and separate species, Martin said. It can give scientists a broader perspective for interpreting data.","Thus, the relatively low (compared with other nodes) discrepancy between mean model estimate and fossil date for node t 13 (34.6%; Table 5 ) may reflect the effect of the near-total absence of a crown strepsirrhine fossil record on both dates rather than relative congruence between the two. Compared with two recent molecular studies of primate divergence dates Young 2006, 2008) , the majority of our estimates are somewhat older (Fig. In most cases, the increases suggested discrepancies between estimated divergence dates and the oldest known fossil representative of a clade.","[3.0, 3.0, 4.0, 4.0]",Biology,test,3.5,news,http://www.usnews.com/science/articles/2010/11/08/new-statistical-model-moves-human-evolution-back-3-million-years 10.1083/jcb.201804028,Biology_159,"And thanks to their newly-developed in vitro approach, in future it will be possible to identify other proteins that operate in the fusion process.","3 G) , suggesting that elevated autophagy is not required to induce the fusion signal.","These results help to understand autophagy and its underlying molecular processes better. And thanks to their newly-developed in vitro approach, in future it will be possible to identify other proteins that operate in the fusion process. Note: material may have been edited for length and content.","Finally, the fusion frequency was similar with cytosolic fractions isolated from cells grown under nutrient-rich conditions and from rapamycin-treated cells ( Fig. 3 G) , suggesting that elevated autophagy is not required to induce the fusion signal. Taken together, we show that autophagosome-vacuole fusion can be recapitulated in vitro, with ypt7Δ autophagosomes, atg15Δ vacuoles, energy, and at least one soluble cytosolic factor.","[1.0, 1.0, 1.0, 2.0]",Biology,test,1.25,news,http://ct.moreover.com/?a=34819790734&p=1pl&v=1&x=8aQKBEotEoZ2dQYDB6dLKA 10.1038/s41598-019-44350-9,Biology_169,The researchers were able to successfully demonstrate through decreased adiposity and an improved metabolic profile the therapeutic potential of targeting NaKtide to the adipocytes.,Our results showed increases in plasma leptin concentrations in mice fed a WD.,"The basis of the research examined more closely the role of the adipocyte in obesity, including how it impacts oxidative stress, inflammation, neurodegeneration and NASH. The researchers were able to successfully demonstrate through decreased adiposity and an improved metabolic profile the therapeutic potential of targeting NaKtide to the adipocytes. ""Our data clearly suggests that obesity and the Na/K-ATPase oxidant amplification loop plays a role in neurodegeneration,"" said first author Rebecca Pratt, a Ph.D. candidate in the department of biomedical research at Marshall University.",Treatment with the lenti-adiponectin-GFP-NaKtide ameliorated the increases in the plasma concentrations of these inflammatory cytokines. Our results showed increases in plasma leptin concentrations in mice fed a WD. This was attenuated by treatment with lenti-adiponectin-GFP-NaKtide ( Fig.,"[1.0, 1.0, 1.0, 3.0]",Biology,test,1.5,news,http://ct.moreover.com/?a=39358808843&p=1pl&v=1&x=pKbzYhsPxx5njcLIUcmXsA 10.1038/s41598-019-44350-9,Biology_174,The researchers were able to successfully demonstrate through decreased adiposity and an improved metabolic profile the therapeutic potential of targeting NaKtide to the adipocytes.,"Our results showed that PGC1α levels, the master regulator of mitochondrial biogenesis and adaptive thermogenesis 36 , increased upon adipocyte-targeted NaKtide expression.","The basis of the research examined more closely the role of the adipocyte in obesity, including how it impacts oxidative stress, inflammation, neurodegeneration and NASH. The researchers were able to successfully demonstrate through decreased adiposity and an improved metabolic profile the therapeutic potential of targeting NaKtide to the adipocytes. ""Our data clearly suggests that obesity and the Na/K-ATPase oxidant amplification loop plays a role in neurodegeneration,"" said first author Rebecca Pratt, a Ph.D. candidate in the department of biomedical research at Marshall University.","This highlights the importance of the Na/K-ATPase oxidant amplification loop within the adipocyte as well as the importance of adipocyte biology itself. Our results showed that PGC1α levels, the master regulator of mitochondrial biogenesis and adaptive thermogenesis 36 , increased upon adipocyte-targeted NaKtide expression. Furthermore, the expression of genes associated with mitochondrial biogenesis and ""browning"" of fat, including MFN1, MFN2, and SIRT1, were increased by NaKtide treatment.","[3.0, 4.0, 5.0, 1.0, 3.0]",Biology,test,4.0,news,http://ct.moreover.com/?a=39358808843&p=1pl&v=1&x=pKbzYhsPxx5njcLIUcmXsA 10.1186/1472-6785-14-23,Biology_179,"When the creosote was a new addition to the diet of individual N.bryanti woodrats, they had different reactions.",There were significant differences in expression related to experience with creosote between N. bryanti populations.,"We expected a huge list of genes -- instead we found very few."" When the creosote was a new addition to the diet of individual N.bryanti woodrats, they had different reactions. They exhibited signs of severe stress, showing that because they hadn't been exposed to the diet, the genes to detoxify it hadn't been switched on.","All other biotransformation transcripts across all groups exhibited inductions of 7-fold or less. There were significant differences in expression related to experience with creosote between N. bryanti populations. Although the total number of transcripts with greater expression in both the experienced and naïve was similar (199 in experienced vs. 183 naïve, [Table 2A with list of genes in Additional file 3: Table S2 ]), the experienced population expressed absolutely twice as many transcripts for biotransformation enzymes (Table 2A, Χ 2 = 14 .72, df = 1, p < 0.001).","[4.0, 2.0, 4.0, 5.0, 3.0]",Biology,test,3.6,news,http://www.sciencedaily.com/releases/2014/08/140815102324.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29 10.1038/ng.3239,Biology_180,The degree of mental disability and related problems was greater in the latter group.,"Comparing the allele frequency of the 6 KCNA2 nonsynonymous variants in our validation cohorts (6/(354 × 2); excluding the first mutation encoding p.Pro405Leu detected in the discovery cohort of 33 patients) with those of missense and nonsense variants reported in the largest available control database (ExAC; 144/122,828) showed a significant enrichment of KCNA2 variants in our patient cohorts using Fisher's exact test (P = 2.6 × 10 −4 ).","For patients with increased function, however, epileptic seizures began even earlier and recurred into adulthood. The degree of mental disability and related problems was greater in the latter group. For patients whose potassium flows are too high, there is an immediate treatment option in the form of 4-aminopyridine, an approved drug which specifically blocks the relevant ion channel.","Similarly, patient 7 carrying the de novo mutation c.890G>A (encoding p.Arg297Gln) presented with a more severe phenotype consisting of moderate intellectual disability, moderate to severe ataxia and pharmacoresistant seizures. Comparing the allele frequency of the 6 KCNA2 nonsynonymous variants in our validation cohorts (6/(354 × 2); excluding the first mutation encoding p.Pro405Leu detected in the discovery cohort of 33 patients) with those of missense and nonsense variants reported in the largest available control database (ExAC; 144/122,828) showed a significant enrichment of KCNA2 variants in our patient cohorts using Fisher's exact test (P = 2.6 × 10 −4 ). Further statistical evidence is provided in the Supplementary Note.","[3.0, 3.0, 1.0, 2.0, 2.0]",Biology,test,2.2,news,http://www.sciencedaily.com/releases/2015/03/150311081755.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29 10.1186/s13287-015-0250-7,Biology_20,Tissues from equine cadaver ligaments up to 72 hours of post-mortem: a promising reservoir of stem cells.,This study demonstrated that a viable stem cell population can be isolated and expanded from equine cadaver ligaments up to 72 hours post-mortem.,"Tissues from equine cadaver ligaments up to 72 hours of post-mortem: a promising reservoir of stem cells. Phase contrast microscopy revealed that cells with fibroblast-like appearance were predominant in the culture. Differentiation assays proved that EC-MSCs are able to differentiate towards mesodermal lineages (osteogenic, adipogenic, chondrogenic).","These observations are also in accordance with another study on ultrastructural changes of MSCs during neuronal induction . This study demonstrated that a viable stem cell population can be isolated and expanded from equine cadaver ligaments up to 72 hours post-mortem. Differentiation assays, flow cytometry, immunofluorescence and TEM analyses confirmed the stemness of these cells.","[5.0, 5.0, 5.0]",Biology,test,5.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/6X1w7O2uQ6Y/ 10.1038/ng.3239,Biology_200,"aEURoeThat is why identifying each mutation in the ion channel is important for diagnosing the individual epilepsy syndrome and finding ways of treating it,aEUR says Professor Holger Lerche, of TA 1/4 bingenaEUR(tm)s Hertie Institute for Clinical Brain Research (HIH) and medical director of Neurology and Epileptology at the TA 1/4 bingen University Hospitals.","Screening a pilot cohort of 33 patients, we identified mutations in known epilepsy-related genes in 16 cases 17 .","aEURoeThe potassium channel KCNA2 is one of many channels. aEURoeThat is why identifying each mutation in the ion channel is important for diagnosing the individual epilepsy syndrome and finding ways of treating it,aEUR says Professor Holger Lerche, of TA 1/4 bingenaEUR(tm)s Hertie Institute for Clinical Brain Research (HIH) and medical director of Neurology and Epileptology at the TA 1/4 bingen University Hospitals. The researchers discovered that the mutations disrupt the ion channelaEUR(tm)s function either by cutting the flow of potassium, leading to a loss of function; or by increasing potassium flow, leading to an excess gain of function.","Therefore, potassium channel genes represent interesting candidates for neurodevelopmental disorders. Screening a pilot cohort of 33 patients, we identified mutations in known epilepsy-related genes in 16 cases 17 . We evaluated the remaining 17 cases for mutations in candidate genes (Supplementary Note), which led to the detection of a heterozygous de novo mutation in KCNA2, c.1214C>T (encoding p.Pro405Leu), affecting the highly conserved pore domain of the voltage-gated potassium channel K V 1.2 (NM_004974, CCDS827).","[3.0, 3.0, 2.0, 3.0]",Biology,test,2.75,news,http://healthmedicinet.com/news/european-scientists-identify-gene-linked-with-certain-types-of-early-onset-epilepsy/ 10.1016/j.immuni.2017.07.015,Biology_202,"They found that adding permeable alpha-ketoglutarate to the low interleukin 2 condition induced about a third of the gene program induced by high interleukin 2 relative to low interleukin 2 in T cells, while it inhibited about 10 percent of the genes that were more highly expressed in low interleukin 2 relative to high interleukin 2 conditions.","Additionally, nearly 80% of the genes that were aKG-sensitive were also IL-2-sensitive (Figures 2A and 2B ).","These different concentrations of interleukin 2 signaling drive the cells to turn on different gene programs and develop gene programs similar to those from either effector or memory T cells. They found that adding permeable alpha-ketoglutarate to the low interleukin 2 condition induced about a third of the gene program induced by high interleukin 2 relative to low interleukin 2 in T cells, while it inhibited about 10 percent of the genes that were more highly expressed in low interleukin 2 relative to high interleukin 2 conditions. Alpha-ketoglutarate thus appears to be responsible for part, but not all, of interleukin 2's impact on T cell gene programming.","These data suggest that aKG-sensitive events play a role in both the induction and inhibition of the IL-2-sensitive gene program in CD4 + Th1 and CD8 + Tc1 cells, with aKG-sensitive activities having a greater role in promoting IL-2-inducible events. Additionally, nearly 80% of the genes that were aKG-sensitive were also IL-2-sensitive (Figures 2A and 2B ). This suggests that a substantial portion of the aKG-sensitive program in CD4 + Th1 and CD8 + Tc1 cells relates to the IL-2-sensitive program.","[2.0, 3.0, 4.0, 1.0, 3.0]",Biology,test,2.6,news,http://healthmedicinet.com/news/how-a-nutrient-glutamine-can-control-gene-programs-in-cells/ 10.1038/s41598-019-44350-9,Biology_22,"The results from this study at Marshall University demonstrate that the Na/K-ATPase oxidant amplification loop in adipocytes, or cells specialized for fat storage, when impaired, could cause adipocyte dysfunction, worsening obesity and potentially increasing the severity of related diseases.","In this study, our results showed that targeting of NaKtide specifically to adipocytes was still able to reverse WD-induced changes in metabolic profile, oxidative stress, and inflammation.","""I am very excited about the work in the current Scientific Reports article and the clinical relevance it presents for the role of adipocytes in obesity and other disease states,"" said Komal Sodhi, M.D., senior author, and associate professor of surgery and biomedical sciences at the Joan C. Edwards School of Medicine. The results from this study at Marshall University demonstrate that the Na/K-ATPase oxidant amplification loop in adipocytes, or cells specialized for fat storage, when impaired, could cause adipocyte dysfunction, worsening obesity and potentially increasing the severity of related diseases. The basis of the research examined more closely the role of the adipocyte in obesity, including how it impacts oxidative stress, inflammation, neurodegeneration and NASH.","S6 B-F. N = 12-14/group; *p < 0.05 vs. CTR, **p < 0.01 vs. CTR, # p < 0.05 vs. WD, ## p < 0.01 vs. WD. In this study, our results showed that targeting of NaKtide specifically to adipocytes was still able to reverse WD-induced changes in metabolic profile, oxidative stress, and inflammation. This highlights the importance of the Na/K-ATPase oxidant amplification loop within the adipocyte as well as the importance of adipocyte biology itself.","[4.0, 2.0, 2.0]",Biology,test,2.6666666666666665,news,http://ct.moreover.com/?a=39358808843&p=1pl&v=1&x=pKbzYhsPxx5njcLIUcmXsA 10.1098/rspb.2014.2335,Biology_226,"But the remarkably high rate of infection during hibernation leads to high mortality rates at the time of year when bat populations are naturally at their lowest, before the females give birth in the summer.","Increases in infectiousness as the fungus grows on hibernating bats may drive winter transmission, with loads increasing throughout the winter.","Bats that survive the winter are able to clear the infection during summer when their body temperatures are above the growth limit of the fungus. But the remarkably high rate of infection during hibernation leads to high mortality rates at the time of year when bat populations are naturally at their lowest, before the females give birth in the summer. The study provides the first description of the dynamics of fungal infection and transmission in bats, and the findings are in striking contrast to most infectious diseases, said senior author Marm Kilpatrick, associate professor of ecology and evolutionary biology at UC Santa Cruz.","If contact with an environmental reservoir drives transmission, then prevalence would be predicted to increase significantly as bats contact infected environments. Increases in infectiousness as the fungus grows on hibernating bats may drive winter transmission, with loads increasing throughout the winter. Phenology varies by latitude; bats in southern sites have shorter hibernation seasons, swarm later in the autumn and return to maternity colonies earlier .","[4.0, 5.0, 3.0, 4.0, 3.0]",Biology,test,3.8,news,http://www.sciencedaily.com/releases/2014/12/141203084101.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29 10.1016/j.immuni.2017.07.015,Biology_255,"They found that adding permeable alpha-ketoglutarate to the low interleukin 2 condition induced about a third of the gene program induced by high interleukin 2 relative to low interleukin 2 in T cells, while it inhibited about 10 percent of the genes that were more highly expressed in low interleukin 2 relative to high interleukin 2 conditions.","In addition, not all pathways, including the cell cycle G2M checkpoint, that were induced by strong IL-2 signaling were also regulated by aKG (Figure 1 , 2, and S2).","These different concentrations of interleukin 2 signaling drive the cells to turn on different gene programs and develop gene programs similar to those from either effector or memory T cells. They found that adding permeable alpha-ketoglutarate to the low interleukin 2 condition induced about a third of the gene program induced by high interleukin 2 relative to low interleukin 2 in T cells, while it inhibited about 10 percent of the genes that were more highly expressed in low interleukin 2 relative to high interleukin 2 conditions. Alpha-ketoglutarate thus appears to be responsible for part, but not all, of interleukin 2's impact on T cell gene programming.","Of note, not all genes that were induced by aKG in the low IL-2 condition were expressed to the same magnitude as compared to the high IL-2 condition. In addition, not all pathways, including the cell cycle G2M checkpoint, that were induced by strong IL-2 signaling were also regulated by aKG (Figure 1 , 2, and S2). There was also some divergence in the identity of the genes with defined effector functions and some variability in the magnitude for the aKG-sensitive induction of genes between CD4 + Th1 and CD8 + Tc1 cells (Figure 1 , 2, and S2).","[4.0, 3.0, 3.0]",Biology,test,3.333333333333333,news,http://healthmedicinet.com/news/how-a-nutrient-glutamine-can-control-gene-programs-in-cells/ 10.3168/jds.2015-10517,Biology_261,"""In less than 24 hours, because we'd already sequenced Chief and his carrier son, we were able to identify a 'nonsense' mutation on chromosome 5.","If available, sequence for an animal homozygous for Chief's normal haplotype could also rule out those mutations.","He and coauthor Heather Adams were able to quickly identify a candidate. ""In less than 24 hours, because we'd already sequenced Chief and his carrier son, we were able to identify a 'nonsense' mutation on chromosome 5. It was a eureka moment,"" Lewin says.","Chief, Mark, Ivanhoe Chief, and Valiant were sequenced to ~31×, 13.5×, ~50×, and ~36× coverage, respectively (Supplementary Table S1 ; http://dx.doi.org/10.3168/jds.2015-10517). If available, sequence for an animal homozygous for Chief's normal haplotype could also rule out those mutations. Analysis of Chief's DNA within the critical region revealed 3 unique SNP in exons, with the rest being intronic, intergenic, 3 UTR, and downstream regions (Table 4 ).","[1.0, 1.0, 2.0, 5.0, 1.0]",Biology,test,1.0,news,http://www.futurity.org/pawnee-farm-arlinda-chief-cows-1273492-2/ 10.1083/jcb.201804028,Biology_276,Kraft and her colleagues have now managed to confirm that the fusion of the autophagosomes and vacuoles is also a process driven by SNARE proteins and that three already-known SNAREs are operative in the fusion process.,One representative experiment out of three is shown.,"Kraft and her colleagues have now managed to confirm that the fusion of the autophagosomes and vacuoles is also a process driven by SNARE proteins and that three already-known SNAREs are operative in the fusion process. They also discovered the fourth necessary SNARE, now called Ykt6. These results help to understand autophagy and its underlying molecular processes better.","One representative experiment out of three is shown. One representative experiment out of three is shown. and Snc1/Snc2, and SNA RE proteins on late endosomes are Pep12, Syn8, Vti1, and Ykt6.","[1.0, 1.0, 1.0, 1.0, 1.0]",Biology,test,1.0,news,http://ct.moreover.com/?a=34812379595&p=1pl&v=1&x=Ob9IjFBAc2hSTNzNa1Xy9A 10.1098/rspb.2014.2335,Biology_279,"If scientists can develop an effective treatment, for example, this study indicates that the best time to apply it would probably be early winter, Langwig said.","Therefore, applying treatments that reduce or clear infection during the autumn and early winter would be most effective for reducing transmission, impacts and spread to new sites.","The study provides valuable information for planning strategies to manage white-nose syndrome. If scientists can develop an effective treatment, for example, this study indicates that the best time to apply it would probably be early winter, Langwig said. Then they plan to use the most promising bacteria as a treatment to see if it can help bats survive through the winter.","When bats first become infected with P. destructans, loads, and therefore tissue invasion and damage, are relatively low. Therefore, applying treatments that reduce or clear infection during the autumn and early winter would be most effective for reducing transmission, impacts and spread to new sites. However, if treatments offer only short-term protection, our data suggest that treated bats will probably be rapidly re-infected upon return to natural environments owing to exceedingly high infection prevalence in other hosts.","[3.0, 3.0, 5.0, 4.0, 2.0]",Biology,test,3.4,news,http://www.sciencedaily.com/releases/2014/12/141203084101.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29 10.1210/en.2013-1955,Biology_297,"If the prostate stem cells were exposed to BPA before implantation and again as they produced prostate tissue in the mice, 45 percent of the tissue samples had pre-cancerous lesions or cancer.","That these malignant lesions arose from normal prostate epithelium in the relatively short time frame of 2-4 months, as compared to decades in humans, is particularly noteworthy and highlights the potent nature of this EDC on augmenting carcinogenic susceptibility.","Prins found that a third of tissue samples taken from mice fed BPA had either pre-cancerous lesions or prostate cancer, compared to only 12 percent in a control group of mice fed oil. If the prostate stem cells were exposed to BPA before implantation and again as they produced prostate tissue in the mice, 45 percent of the tissue samples had pre-cancerous lesions or cancer. ""We believe that BPA actually reprograms the stem cells to be more sensitive to estrogen throughout life, leading to a life-long increased susceptibility to diseases including cancer,"" Prins said.","This carcinogenic rate further increased to 45% when developmental BPA exposure was extended to in vitro stem cell cultures, implicating the stem-progenitor cells as the direct BPA targets, a hypothesis supported by the in vitro studies discussed above. That these malignant lesions arose from normal prostate epithelium in the relatively short time frame of 2-4 months, as compared to decades in humans, is particularly noteworthy and highlights the potent nature of this EDC on augmenting carcinogenic susceptibility. It is important to emphasize that the stem cells in the present study were cultured from disease-free prostates of young organ donors making it unlikely that the cells had prior initiating events.","[4.0, 2.0, 3.0]",Biology,test,3.0,news,http://www.healthcanal.com/cancers/46375-bpa-increases-risk-of-cancer-in-human-prostate-tissue.html 10.1098/rspb.2014.2335,Biology_298,"Most of the mortality is in late winter, when both infection prevalence (the number of infected bats) and infection loads (the amount of fungus on individual bats) are highest.","Colony sizes among seasons broadly overlapped despite directionally opposite patterns of infection prevalence, suggesting that larger winter colony sizes are not the primary driver of differences in transmission among seasons.","When the bats start hibernating, it's almost like they become petri dishes for this fungus to grow on."" Most of the mortality is in late winter, when both infection prevalence (the number of infected bats) and infection loads (the amount of fungus on individual bats) are highest. ""The peak load in late winter is probably what's driving mortality,"" Langwig said.","Furthermore, for M. lucifugus, transmission was unrelated to seasonal changes in colony size. Colony sizes among seasons broadly overlapped despite directionally opposite patterns of infection prevalence, suggesting that larger winter colony sizes are not the primary driver of differences in transmission among seasons. Although winter colonies affected by WNS decline over the winter, colony sizes would have to be 100 times higher in early winter to alter the qualitative relationship between seasonal colony size and transmission.","[2.0, 1.0, 2.0, 2.0]",Biology,test,1.75,news,http://www.sciencedaily.com/releases/2014/12/141203084101.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29 10.1126/science.1226727,Biology_308,"The diversity of the experts working on the project is just a reflection of the diversity of the arthropods themselves,"" he says.","Reassuringly, our wellresolved estimates of tropical arthropod species richness are of the same order of magnitude as prior estimates (table S3) , adding credence to recent estimates of tropical arthropod diversity (5, 21) .","This means that in the future, scientists can accurately study the diversity of a forest the size of Manhattan by only studying an area equivalent to a few city blocks. The diversity of the experts working on the project is just a reflection of the diversity of the arthropods themselves,"" he says. This large-scale interdisciplinary effort marks a first in the field of tropical entomology, says Basset.","Because this study targeted the full spectrum of arthropods, it offers a comprehensive test of previous estimates of species richness based only on selected guilds or taxa. Reassuringly, our wellresolved estimates of tropical arthropod species richness are of the same order of magnitude as prior estimates (table S3) , adding credence to recent estimates of tropical arthropod diversity (5, 21) . Although the scope for direct comparison is limited because of regional differences in sampling effort, lowland tropical forest in Panama seems to support 2.1 to 8.4 times as many arthropod species as observed in temperate forests (table S3) .","[4.0, 2.0, 2.0, 2.0, 1.0]",Biology,test,2.2,news,http://news.nationalgeographic.com/news/2012/12/13-arthropods-rule-the-tropical-rain-forest/ 10.1126/sciadv.aat6509,Biology_309,This information is useful for risk management because the year 2005 has already been extensively studied and its tropical cyclone hazards and risks to infrastructure are well known.,"By estimating both the mean number of tropical cyclones and their possible year-to-year random variability, we find that the likelihood that the maximum number of storms in the Atlantic could be greater than the number of events observed during the 2005 season is less than 3.5%.","They found the record number of tropical cyclones that occurred in 2005 (28 storms) is close to the maximum number that might occur in this region given existing climate conditions. This information is useful for risk management because the year 2005 has already been extensively studied and its tropical cyclone hazards and risks to infrastructure are well known. Thus, it could serve as a tropical cyclone risk benchmark for future hurricane seasons in this basin.","By estimating both the mean number of tropical cyclones and their possible year-to-year random variability, we find that the likelihood that the maximum number of storms in the Atlantic could be greater than the number of events observed during the 2005 season is less than 3.5%. Using a less restrictive comparison between simulated and observed climate with the internal variability accounted for, this probability increases to 9%; however, the estimated maximum possible number of tropical cyclones does not greatly exceed the 2005 total. Hence, the 2005 season can be used as a risk management benchmark for the maximum possible number of tropical cyclones in the Atlantic.","[2.0, 3.0, 3.0, 4.0, 2.0]",Biology,test,2.8,news,http://ct.moreover.com/?a=34894577018&p=1pl&v=1&x=VxqXy1WNQjnOFbklii8AEg 10.1038/ng.3239,Biology_316,"For patients with increased function, however, epileptic seizures began even earlier and recurred into adulthood.",Two further individuals presented with a different and more severe epileptic encephalopathy phenotype.,"Patients demonstrating a loss of function had their first epileptic seizures starting at the age of around one, but the attacks ceased during childhood or in the patientaEUR(tm)s teenage years. For patients with increased function, however, epileptic seizures began even earlier and recurred into adulthood. The degree of mental disability and related problems was greater in the latter group.",Functional studies of the two mutations associated with this phenotype showed almost complete loss of function with a dominant-negative effect. Two further individuals presented with a different and more severe epileptic encephalopathy phenotype. They carried mutations inducing a drastic gain-of-function effect leading to permanently open channels.,"[4.0, 2.0, 3.0, 3.0]",Biology,test,3.0,news,http://healthmedicinet.com/news/european-scientists-identify-gene-linked-with-certain-types-of-early-onset-epilepsy/ 10.1016/j.immuni.2017.07.015,Biology_338,"They found that adding permeable alpha-ketoglutarate to the low interleukin 2 condition induced about a third of the gene program induced by high interleukin 2 relative to low interleukin 2 in T cells, while it inhibited about 10 percent of the genes that were more highly expressed in low interleukin 2 relative to high interleukin 2 conditions.","In the qRT-PCR analyses, IL-2-and aKG-sensitive genes, including Hk2, Ifng, and Hlx, were induced by 5-aza treatment to a similar extent as aKG treatment (Figure 3D ).","These different concentrations of interleukin 2 signaling drive the cells to turn on different gene programs and develop gene programs similar to those from either effector or memory T cells. They found that adding permeable alpha-ketoglutarate to the low interleukin 2 condition induced about a third of the gene program induced by high interleukin 2 relative to low interleukin 2 in T cells, while it inhibited about 10 percent of the genes that were more highly expressed in low interleukin 2 relative to high interleukin 2 conditions. Alpha-ketoglutarate thus appears to be responsible for part, but not all, of interleukin 2's impact on T cell gene programming.","The qRT-PCR analyses demonstrated that several IL-2-and aKG-sensitive target genes had decreased expression with Tet2 knockdown ( Figure S3E ). In the qRT-PCR analyses, IL-2-and aKG-sensitive genes, including Hk2, Ifng, and Hlx, were induced by 5-aza treatment to a similar extent as aKG treatment (Figure 3D ). The inhibition of DNA methylation diminished the expression of genes such as Klf2 and Sell (encodes CD62L) to a similar extent that aKG inhibited their expression.","[3.0, 2.0, 2.0, 2.0]",Biology,test,2.25,news,http://healthmedicinet.com/news/how-a-nutrient-glutamine-can-control-gene-programs-in-cells/ 10.1210/en.2013-1955,Biology_345,"If you're drinking from a water bottle or eating from a plastic container, chances are you're consuming it right now.","This carcinogenic rate further increased to 45% when developmental BPA exposure was extended to in vitro stem cell cultures, implicating the stem-progenitor cells as the direct BPA targets, a hypothesis supported by the in vitro studies discussed above.","""Our research provides the first direct evidence that exposure to BPA during development, at the levels we see in our day-to-day lives, increases the risk for prostate cancer in human prostate tissue,"" Gail Prins, a professor of physiology and lead author of the paper, said in a press release. If you're drinking from a water bottle or eating from a plastic container, chances are you're consuming it right now. According to the study authors, avoiding the chemical altogether is a next-to impossible feat.","In vivo BPA exposure during the time of stemprogenitor cell lineage commitment, differentiation and formation of glandular epithelium significantly boosted the rate of T+E driven carcinogenesis from 13% in vehicle exposed hosts to 33-36% malignancy. This carcinogenic rate further increased to 45% when developmental BPA exposure was extended to in vitro stem cell cultures, implicating the stem-progenitor cells as the direct BPA targets, a hypothesis supported by the in vitro studies discussed above. That these malignant lesions arose from normal prostate epithelium in the relatively short time frame of 2-4 months, as compared to decades in humans, is particularly noteworthy and highlights the potent nature of this EDC on augmenting carcinogenic susceptibility.","[3.0, 2.0, 1.0, 1.0]",Biology,test,1.75,news,http://www.medicaldaily.com/bpa-exposure-utero-may-triple-risk-prostate-cancer-can-we-do-anything-about-it-266535 10.1098/rsbl.2018.0484,Biology_347,"For the algorithms in the data loggers to recognize the caller's species, however, the sound source had to be closer to the devices, an issue that would affect researchers working in areas with more than one echolocating species.","Over the entire deployment period, relatively high ambient noise levels were mainly caused by vessel noise and were above 120 dB re 1 mPa 11% of the time (electronic supplementary material, figures S4 and S5).","The maximum distance a data logger captured the sounds was 566 meters (1,857 feet), though the average EDR among the data loggers was just under 200 meters (656 feet) for both real and artificial porpoise click signals. For the algorithms in the data loggers to recognize the caller's species, however, the sound source had to be closer to the devices, an issue that would affect researchers working in areas with more than one echolocating species. In this case, the algorithms' EDR for clicks correctly classified as porpoise sounds was just 72 meters (236 feet).","Increased noise in the 40 Hz, 400 Hz and 10 kHz TOLs also had significant effects on dolphin whistle characteristics (table 1) . Over the entire deployment period, relatively high ambient noise levels were mainly caused by vessel noise and were above 120 dB re 1 mPa 11% of the time (electronic supplementary material, figures S4 and S5). The dolphin whistles had a less complex contour shape during increased ambient noise in the 2.5 and 20 kHz TOLs.","[2.0, 3.0, 2.0, 1.0, 2.0]",Biology,test,2.0,news,http://ct.moreover.com/?a=37573910184&p=1pl&v=1&x=e06RfMvoJ4XWimX-jmzWKg 10.1210/en.2013-1955,Biology_349,"In tissue samples taken from a control group, the figure was 12 percent.",The incidence of prostate intraepithelial neoplasia (HG-PIN) and adenocarcinoma markedly increased from 13% in oil-fed controls to 33-36% in grafts exposed in vivo to BPA (P<0.05).,"The team found that about one-third of tissue samples taken from mice fed BPA showed signs of prostate cancer or precancerous lesion. In tissue samples taken from a control group, the figure was 12 percent. ""The findings of adverse effects of BPA in human tissue are highly relevant and should encourage agencies like the Food & Drug Administration to re-evaluate their policies in the near future,"" Prins said of the results.","Together, the present findings demonstrate that human prostate stem-progenitor cells are direct BPA targets and that developmental exposure to BPA at low-doses increases hormone dependent cancer risk in the human prostate epithelium. The incidence of prostate intraepithelial neoplasia (HG-PIN) and adenocarcinoma markedly increased from 13% in oil-fed controls to 33-36% in grafts exposed in vivo to BPA (P<0.05). Continuous developmental BPA exposure through in vitro (200 nM) plus in vivo (250 µg/kg BW) treatments increased HG-PIN/cancer incidence to 45% (P< 0.01).","[1.0, 1.0, 1.0]",Biology,test,1.0,news,http://www.medicaldaily.com/bpa-exposure-utero-may-triple-risk-prostate-cancer-can-we-do-anything-about-it-266535 10.1186/s13287-015-0250-7,Biology_35,"CONCLUSIONS: Our findings raise the prospect that the tissues harvested from equine ligaments up to 72 hours of post-mortem represent an available reservoir of specific stem cells.",This study demonstrated that a viable stem cell population can be isolated and expanded from equine cadaver ligaments up to 72 hours post-mortem.,"Furthermore, TEM analysis confirmed the stemness of EC-MSCs and identified some cells with a typical neuronal morphology. CONCLUSIONS: Our findings raise the prospect that the tissues harvested from equine ligaments up to 72 hours of post-mortem represent an available reservoir of specific stem cells. EC-MSCs could be a promising alternative source for tissue engineering and stem cell therapy in equine medicine.","These observations are also in accordance with another study on ultrastructural changes of MSCs during neuronal induction . This study demonstrated that a viable stem cell population can be isolated and expanded from equine cadaver ligaments up to 72 hours post-mortem. Differentiation assays, flow cytometry, immunofluorescence and TEM analyses confirmed the stemness of these cells.","[5.0, 5.0, 5.0, 5.0]",Biology,test,5.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/6X1w7O2uQ6Y/ 10.1038/s41559-019-0899-x,Biology_353,The special feature of the method is that only limited information is needed about the characteristics of 'predators' that hunt prey animals.,"Predators typically exert the strongest feeding pressure on prey that are 1-2 orders of magnitude smaller 1 , while weaker interaction strengths are realized with prey that are smaller or larger than this size 11 .","The special feature of the method is that only limited information is needed about the characteristics of 'predators' that hunt prey animals. These data enable researchers to determine the structure and stability of a habitat, without the need for a comprehensive examination of the relationships to other organisms. The scientists were able to confirm the value of their method using a large dataset of 220,000 interactions from 290 food webs.","The varying body-mass ratios limit which trophic interactions are realized in a community , and the strength of these interactions . Predators typically exert the strongest feeding pressure on prey that are 1-2 orders of magnitude smaller 1 , while weaker interaction strengths are realized with prey that are smaller or larger than this size 11 . Moreover, they also buffer natural communities against perturbations from global warming","[4.0, 3.0, 3.0, 2.0]",Biology,test,3.0,news,http://ct.moreover.com/?a=39271353921&p=1pl&v=1&x=B7TN33xQfGdJisQOcwCwJw 10.1186/1472-6785-14-23,Biology_354,"Dr Malenke says: ""For N. bryanti but not for N. lepida, there appears to be a hidden strategy of maintaining expression of exactly the right combination of enzymes to suit the animal's 'normal' diet and not altering that expression, even with a change in diet.",Major evolutionary dietary shifts seem to be enabled by an underlying change in biotransformation enzymes .,"They exhibited signs of severe stress, showing that because they hadn't been exposed to the diet, the genes to detoxify it hadn't been switched on. Dr Malenke says: ""For N. bryanti but not for N. lepida, there appears to be a hidden strategy of maintaining expression of exactly the right combination of enzymes to suit the animal's 'normal' diet and not altering that expression, even with a change in diet. Although very efficient, this strategy might be a disadvantage, say, in the face of a climate change event.""",The response of the naïve woodrat population to creosote bush was indicative of extreme physiological stress. Major evolutionary dietary shifts seem to be enabled by an underlying change in biotransformation enzymes . Surprisingly few alterations among myriad biotransformation enzymes are required for a change in the capacity to metabolize a new toxin.,"[1.0, 3.0, 2.0, 3.0]",Biology,test,2.25,news,http://www.sciencedaily.com/releases/2014/08/140815102324.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29 10.1038/s41598-019-44350-9,Biology_364,"""I am very excited about the work in the current Scientific Reports article and the clinical relevance it presents for the role of adipocytes in obesity and other disease states,"" said Komal Sodhi, M.D., senior author, and associate professor of surgery and biomedical sciences at the Joan C. Edwards School of Medicine.",This was prevented by lenti-adiponectin-GFP-NaKtide treatment ( Fig.,"""I am very excited about the work in the current Scientific Reports article and the clinical relevance it presents for the role of adipocytes in obesity and other disease states,"" said Komal Sodhi, M.D., senior author, and associate professor of surgery and biomedical sciences at the Joan C. Edwards School of Medicine. The results from this study at Marshall University demonstrate that the Na/K-ATPase oxidant amplification loop in adipocytes, or cells specialized for fat storage, when impaired, could cause adipocyte dysfunction, worsening obesity and potentially increasing the severity of related diseases. The basis of the research examined more closely the role of the adipocyte in obesity, including how it impacts oxidative stress, inflammation, neurodegeneration and NASH.","Expression of the α1 subunit of the Na/K-ATPase was significantly down regulated in visceral fat of mice fed a WD. This was prevented by lenti-adiponectin-GFP-NaKtide treatment ( Fig. Conversely, the up-regulated expression of the α2 subunit in mice fed a WD was significantly attenuated by lenti-adiponectin-GFP-NaKtide ( Fig.","[1.0, 2.0, 1.0]",Biology,test,1.3333333333333333,news,http://ct.moreover.com/?a=39358808843&p=1pl&v=1&x=pKbzYhsPxx5njcLIUcmXsA 10.1210/en.2013-1955,Biology_385,"""The amount of BPA we fed the mice was equivalent to levels ingested by the average person,"" Prins said.","Similar to estradiol-17 (E2), BPA increased stem-progenitor cell self-renewal and expression of stem-related genes in a dose-dependent manner.","""The findings of adverse effects of BPA in human tissue are highly relevant and should encourage agencies like the Food & Drug Administration to re-evaluate their policies in the near future."" ""The amount of BPA we fed the mice was equivalent to levels ingested by the average person,"" Prins said. ""We didn't feed them exorbitantly high doses.""","Similar to estradiol-17 (E2), BPA increased stem-progenitor cell self-renewal and expression of stem-related genes in a dose-dependent manner. Further, 10 nM BPA and E2 possessed equimolar membrane-initiated signaling with robust induction of p-Akt and p-Erk at 15 min. The incidence of prostate intraepithelial neoplasia (HG-PIN) and adenocarcinoma markedly increased from 13% in oil-fed controls to 33-36% in grafts exposed in vivo to BPA (P<0.05).","[2.0, 4.0, 3.0, 1.0, 1.0]",Biology,test,2.2,news,http://www.healthcanal.com/cancers/46375-bpa-increases-risk-of-cancer-in-human-prostate-tissue.html 10.1098/rspb.2014.2335,Biology_392,"The researchers began to detect low levels of fungal infection in the fall, probably as a result of bats coming in contact with spores of the fungus inside the hibernacula.",The rapid increase in prevalence between late autumn and early hibernation could have been caused by the large increase in loads which increased infectiousness.,"""Bats that survive the winter can clear the fungal infection once they warm up, so that by mid-summer, when the young of the year are born, almost no bats are infected any more."" The researchers began to detect low levels of fungal infection in the fall, probably as a result of bats coming in contact with spores of the fungus inside the hibernacula. ""The bats are still active then, so the infections are at a very low level and don't appear to be growing.","Fungal loads also increased substantially with the onset of hibernation. The rapid increase in prevalence between late autumn and early hibernation could have been caused by the large increase in loads which increased infectiousness. Temperatures of bats during hibernation are approximately the same as ambient temperatures of hibernacula , and are within the range of temperatures that the pathogen can grow , resulting in explosive amplification of P. destructans on hibernating bats.","[4.0, 3.0, 4.0, 2.0]",Biology,test,3.25,news,http://www.sciencedaily.com/releases/2014/12/141203084101.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29 10.1098/rstb.2018.0272,Biology_394,"Population displacement can also affect the spread of vector-borne disease in a few ways, the researchers found.","If these characteristics are correlated with mobility, and if evacuations are voluntary, we would expect Twitter data to overestimate the percentage of the population displaced.","Considering that mosquitos have an average lifespan of less than two weeks, that temperature difference can have a dramatic effect on disease outbreaks."" Population displacement can also affect the spread of vector-borne disease in a few ways, the researchers found. When people opt to leave the area, it reduces the number of local infections, while potentially increasing the number of infections elsewhere.","Data streams from these sources could be useful to quantify the level of public awareness during emergencies and may provide a useful proxy of the temporal profile of population displacement patterns away from the affected areas. If these characteristics are correlated with mobility, and if evacuations are voluntary, we would expect Twitter data to overestimate the percentage of the population displaced. More accurate data on both evacuees and emergency responders would help improve projections of disease risks.","[1.0, 1.0, 2.0]",Biology,test,1.3333333333333333,news,http://ct.moreover.com/?a=39454767451&p=1pl&v=1&x=t_1mmmyJBvTAz09R9w2bgA 10.1210/en.2013-1955,Biology_42,"""We believe that BPA actually reprograms the stem cells to be more sensitive to estrogen throughout life, leading to a life-long increased susceptibility to diseases including cancer,"" Prins said.","Together, these data contribute to the increasing body of evidence for a link between fetal exposures to EDCs and cancer .","""The findings of adverse effects of BPA in human tissue are highly relevant and should encourage agencies like the Food & Drug Administration to re-evaluate their policies in the near future."" The amount of BPA given to the mice was equal to the levels an average person ingests. ""We believe that BPA actually reprograms the stem cells to be more sensitive to estrogen throughout life, leading to a life-long increased susceptibility to diseases including cancer,"" Prins said.","The present findings provide the first evidence that exposure of the developing human prostate epithelium to BPA at relevant human exposure levels markedly increases the incidence of prostate carcinogenesis in the mature epithelium exposed to elevated estradiol. Together, these data contribute to the increasing body of evidence for a link between fetal exposures to EDCs and cancer . In vivo BPA exposure during the time of stemprogenitor cell lineage commitment, differentiation and formation of glandular epithelium significantly boosted the rate of T+E driven carcinogenesis from 13% in vehicle exposed hosts to 33-36% malignancy.","[1.0, 1.0, 4.0, 2.0]",Biology,test,1.0,news,http://www.scienceworldreport.com/articles/12081/20140110/fetal-exposure-to-chemicals-in-plastic-bottles-increases-risk-of-prostate-cancer-later-study-confirms.htm 10.1038/s41467-019-09455-9,Biology_422,"Then the team identified 27 unique bacterial features unique to the gut microbiomes, and thus stool, of people with NAFLD-cirrhosis.",This study leverages from a unique and well-characterized cohort including participants with NAFLD-cirrhosis which allows studying the specific gutmicrobiome signature of this extreme and well-defined clinical phenotype.,"In addition, they observed that people with extreme forms of NAFLD had less diverse and less stable gut microbiomes. Then the team identified 27 unique bacterial features unique to the gut microbiomes, and thus stool, of people with NAFLD-cirrhosis. The researchers were able to use this noninvasive stool test to pick out the people with known NAFLD-cirrhosis with 92 percent accuracy.","Hence, this conveniently assessed microbial biomarker could present an adjunct tool to current invasive approaches to determine stage of liver disease. This study leverages from a unique and well-characterized cohort including participants with NAFLD-cirrhosis which allows studying the specific gutmicrobiome signature of this extreme and well-defined clinical phenotype. The fundamental difference between the previous study and the present study is the clinical context of use of the gut-microbiome signature.","[2.0, 5.0, 4.0, 4.0]",Biology,test,3.75,news,http://ct.moreover.com/?a=38870549139&p=1pl&v=1&x=CJ-Fxx_sD-uG7lPfAXCKQg 10.1073/pnas.1815660115,Biology_429,"The study also demonstrates that by reducing p53, DnaK can also reduce the efficacy of anti-cancer drugs.","Eight animals were injected with nonviable mycoplasma, and none developed lymphoma up to 28 wk of age (see also Materials and Methods).","The scientists noted that the bacteria can release DnaK and the DnaK enters nearby uninfected cells. The study also demonstrates that by reducing p53, DnaK can also reduce the efficacy of anti-cancer drugs. Thus, mycoplasma infection could not only trigger events leading to the accumulation of DNA damage and oncogenesis in infected cells, but also trigger cancer-causing events in nearby uninfected cells that took up DnaK released from infected neighboring cells.","Seven animals died of wasting within 30 wk after infection, and none of the remaining animals developed lymphoma. Eight animals were injected with nonviable mycoplasma, and none developed lymphoma up to 28 wk of age (see also Materials and Methods). Uninfected spleens showed very little variation in size and were considered as references in comparing the size of spleen from infected animals.","[2.0, 1.0, 1.0]",Biology,test,1.3333333333333333,news,https://www.sciencedaily.com/releases/2018/12/181204155158.htm 10.1126/scitranslmed.3007096,Biology_432,"""The CHI3L1 is doing exactly what it is supposed to do -- it is designed to shut off cell death and decrease injury,"" said Dr. Jack A. Elias, a co-senior author of the study and dean of medicine and biological sciences at Brown University.",these observations raise the possibility that CHI3L1 might also be a useful therapeutic that could control tissue injury.,"In IPF, 70 percent of patients die within five years. ""The CHI3L1 is doing exactly what it is supposed to do -- it is designed to shut off cell death and decrease injury,"" said Dr. Jack A. Elias, a co-senior author of the study and dean of medicine and biological sciences at Brown University. ""But at the same time it is decreasing cell death it is driving the fibrosis.","n = 6 mice per group. these observations raise the possibility that CHI3L1 might also be a useful therapeutic that could control tissue injury. Its utility in this setting would be further enhanced if subsequent studies define ways to separate the antiapoptotic and fibroproliferative effects of this CLP, allowing the protective effects of the former to manifest without engendering excess scarring.","[4.0, 3.0, 3.0, 3.0]",Biology,test,3.25,news,http://www.sciencedaily.com/releases/2014/06/140611143735.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29 10.1371/journal.pgen.1006135,Biology_437,"The research team also observed that turning off autophagy in the intestine made the slow-eating, long-lived worms move around less.","Interestingly, we observed that intestinal autophagy was required for the motility of eat-2 mutants, highlighting a cell non-autonomous function of autophagy in the intestine.","""It's possible that the decline in the gut's barrier function associated with normal aging might let damaging substances or pathogens into the body."" The research team also observed that turning off autophagy in the intestine made the slow-eating, long-lived worms move around less. ""The decrease in physical activity indicates that autophagy in one organ can have a major impact on other organs, in this case probably muscle or motor neurons,"" said Hansen.","These observations suggest a longevity role for autophagy not only in the intestine but also in body-wall muscle, as suggested in WT mice [ , and indicate differences between the role of basal autophagy versus autophagy induced by DR in maintaining muscle integrity that are still to be elucidated. Interestingly, we observed that intestinal autophagy was required for the motility of eat-2 mutants, highlighting a cell non-autonomous function of autophagy in the intestine. One explanation for this observation is that intestinal inhibition of autophagy may cause deterioration of this organ, as implied by our Smurf assays.","[5.0, 5.0, 4.0, 4.0]",Biology,test,4.5,news,http://healthmedicinet.com/news/dietary-restriction-increases-lifespan-through-effects-on-the-gut/ 10.1126/scitranslmed.aap8307,Biology_455,Metarrestin potentially could be effective as part of combinational therapy after cancer surgery.,Evaluation of apoptotic index showed less than 1% of cells undergoing apoptosis in response to metarrestin treatment.,"""Targeting one thing is not sufficient to stop metastatic cancer."" Metarrestin potentially could be effective as part of combinational therapy after cancer surgery. ""This represents a new strategy for developing anti-cancer drugs,"" Huang said.",S9C ). Evaluation of apoptotic index showed less than 1% of cells undergoing apoptosis in response to metarrestin treatment. Selective inhibition of Pol II by -amanitin induces a localization shift to the cytoplasm except for PNClocalized CUGBP ( fig.,"[1.0, 3.0, 2.0, 2.0]",Biology,test,2.0,news,http://ct.moreover.com/?a=34073189807&p=1pl&v=1&x=8gtafKasCptNEaWA6tmY7Q 10.1126/scitranslmed.3007323,Biology_463,"Compared with unvaccinated lesions, the vaccinated lesions had evidence of lymphoid cell proliferation.","Within-subject increases in tissue CD8 + T cells were significantly greater than the increases we have reported previously in unvaccinated subjects followed over the same time frame (P = 0.0300, fig.","Cervical tissue after vaccination had organized lymphoid-like structures within the surrounding connecting tissue adjacent to the lesions. Compared with unvaccinated lesions, the vaccinated lesions had evidence of lymphoid cell proliferation. The researchers also detected an immune signature within the dysplastic epithelium.","These infiltrates were localized in foci of residual dysplasia, not in immediately adjacent normal mucosa. Within-subject increases in tissue CD8 + T cells were significantly greater than the increases we have reported previously in unvaccinated subjects followed over the same time frame (P = 0.0300, fig. These infiltrates included increased absolute numbers of Tbet + cells, suggestive of an effector T cell response.","[4.0, 3.0, 4.0, 1.0, 4.0]",Biology,test,3.2,news,http://www.cancernetwork.com/cervical-cancer/cancer-regression-therapeutic-hpv-vaccine 10.1111/acel.12344,Biology_465,"Indeed, using transcript analysis, the researchers found that, like cancer cells, senescent cells have increased expression of ""pro-survival networks"" that help them resist apoptosis or programmed cell death.","Similar to cancer cells, here we demonstrated that silencing EFNB ligands induces apoptosis selectively in senescent as compared to nonsenescent cells.","""It may eventually become feasible to delay, prevent, alleviate or even reverse multiple chronic diseases and disabilities as a group, instead of just one at a time."" Indeed, using transcript analysis, the researchers found that, like cancer cells, senescent cells have increased expression of ""pro-survival networks"" that help them resist apoptosis or programmed cell death. This finding provided key criteria to search for potential drug candidates.","EFNB ligands can participate in dependence networks that constrain both the cells they are located on and adjacent cells from undergoing apoptosis . Similar to cancer cells, here we demonstrated that silencing EFNB ligands induces apoptosis selectively in senescent as compared to nonsenescent cells. Silencing EFNB3 expression down-regulates AKT in cancer cells .","[4.0, 5.0, 2.0, 3.0]",Biology,test,3.5,news,http://www.sciencedaily.com/releases/2015/03/150309144823.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29 10.1038/ni.3793,Biology_475,Male animals with the reduced production of Blimp-1 showed no change in their immune system.,"The increased CTSS activity in DCs of female CKO mice led to increased diversity in the TCR repertoire of T FH cells, which was abolished by a CTSS-specific inhibitor.","This resulted in an immune system which attacked healthy cells. Male animals with the reduced production of Blimp-1 showed no change in their immune system. Though more study is required to confirm that the risk gene PRDM1 could lead to a hyperactive immune system in human females, this is a significant discovery to better understanding the causes and potential treatments for lupus.","Thus, Bimp-1 directly and indirectly regulated Ctss expression. The increased CTSS activity in DCs of female CKO mice led to increased diversity in the TCR repertoire of T FH cells, which was abolished by a CTSS-specific inhibitor. These findings suggested that an increase in CTSS expression associated with absent or low expression of Blimp-1 generated a repertoire more skewed toward self-reactivity.","[1.0, 3.0, 1.0, 1.0]",Biology,test,1.5,news,http://healthmedicinet.com/news/feinstein-institute-identifies-potential-cause-for-lupus/ 10.1016/j.ecolind.2018.11.016,Biology_478,"The indicator finds that less than 3 percent of the 7,000 evaluated species are presently classified as ""low priority"" or ""sufficiently conserved.""","While the indicator is robust in that it uses well-established taxonomic, occurrence, and eco-geographic information as inputs, and employs popular open-source software, a number of vulnerabilities of the method should be mentioned.","The indicator finds that less than 3 percent of the 7,000 evaluated species are presently classified as ""low priority"" or ""sufficiently conserved."" This is worrying, say the authors, since the indicator was designed to measure countries' progress toward ambitious conservation goals that are supposed to be met by 2020, including the Convention on Biological Diversity Aichi Target 13 and Sustainable Development Goal 2.5. ""This indicator underscores the urgency to protect the world's useful wild plants.","Therefore, it could serve as a useful complement to existing and proposed indicators for Aichi 13, GSPC 9, SDG 2.5, and Article 5 of the ITPGRFA. While the indicator is robust in that it uses well-established taxonomic, occurrence, and eco-geographic information as inputs, and employs popular open-source software, a number of vulnerabilities of the method should be mentioned. First, the quality of the results is highly dependent on the comprehensiveness and the degree of ongoing curation of the data and technologies used.","[2.0, 1.0, 3.0]",Biology,test,2.0,news,http://ct.moreover.com/?a=37765387389&p=1pl&v=1&x=zbpVQSXLPtFKPlpjt90SgQ 10.1016/j.celrep.2018.06.099,Biology_483,"""The dramatic findings of essentially normal perceptual behavior and normal (albeit rearranged) neural correlates... attest to the power of plasticity of the higher-order visual system,"" Behrmann and colleagues conclude.","In category-selective visual cortices, however, object-and sceneselective regions in the intact left hemisphere were stable early on, but regions subserving face and word recognition emerged later and evinced competition for cortical representation.","The fMRI results over the three-year followup indicated that the left side of his occipital lobe had continued to handle word processing while gradually reorganizing to pick up the slack on facial recognition--a task typically dominated by the right side of the lobe. ""The dramatic findings of essentially normal perceptual behavior and normal (albeit rearranged) neural correlates... attest to the power of plasticity of the higher-order visual system,"" Behrmann and colleagues conclude. While the surgery and reorganization was a triumph for UD--who has also been seizure free since the procedure--the researchers note his case raises a host of new questions.","showed age-appropriate intellectual performance and visuoperceptual face and object recognition skills. In category-selective visual cortices, however, object-and sceneselective regions in the intact left hemisphere were stable early on, but regions subserving face and word recognition emerged later and evinced competition for cortical representation. These findings reveal alterations in the selectivity and topography of category-selective regions when confined to a single hemisphere and provide insights into dynamic functional changes in extrastriate cortical architecture.","[3.0, 2.0, 3.0, 3.0]",Biology,test,2.75,news,http://ct.moreover.com/?a=34695794460&p=1pl&v=1&x=qwFTWEjZEgNOLj7D3fwxxw 10.1111/gcb.12404,Biology_484,"When the team put the two sets of data together, though, along with climate data from the same 150-year period, they could clearly see the link between periods of slow growth and dead trees later on.","Figure 6 shows how ring-width chronology for this old-growth site compares to a chronology computed, using identical methods, from a nearby 85-year-old site (cf.","Bond-Lamberty said this isn't surprising to see in a forest that hasn't seen a wildfire in a long time. When the team put the two sets of data together, though, along with climate data from the same 150-year period, they could clearly see the link between periods of slow growth and dead trees later on. advertisement ""We see a five-year lag between depressed growth in the tree core data and increase of deaths in mortality data,"" said Bond-Lamberty.","The length of this process varies greatly by species and the stressors involved; our 5-year estimate is consistent with a broad range (0-10+ years) reported from forests worldwide . Figure 6 shows how ring-width chronology for this old-growth site compares to a chronology computed, using identical methods, from a nearby 85-year-old site (cf. The strong cross-site correlation (r = 0.55) in Fig.","[4.0, 3.0, 2.0, 2.0]",Biology,test,2.75,news,http://www.sciencedaily.com/releases/2013/10/131002185515.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29 10.1016/j.cmet.2015.05.012,Biology_488,"When the program ended, the participants experienced a reduction of risk factors related to several illnesses including cancer, heart disease, diabetes and aging.",These concerns point to the need for dietary interventions that induce PF-like effects while minimizing the risk of adverse effects and the burden of complete food restriction.,"It provided them with around 34 percent to 54 percent of their normal calorie intake made up of 11 percent to 14 percent of proteins, 42 percent to 43 percent of carbohydrates and 44 percent to 46 percent of fat. When the program ended, the participants experienced a reduction of risk factors related to several illnesses including cancer, heart disease, diabetes and aging. ""This is arguably the first non-chronic pre-clinically and clinically tested anti-aging and healthspan-promoting intervention shown to work and to be very feasible as a doctor or dietitian-supervised intervention,"" Longo said.","In humans, IF and less-severe regimens (e.g., consumption of approximately 500 kcal/day for 2 days a week) have beneficial effects on insulin, glucose, C-reactive protein, and blood pressure . These concerns point to the need for dietary interventions that induce PF-like effects while minimizing the risk of adverse effects and the burden of complete food restriction. PF cycles extended both medium and maximum chronological lifespan (Figures 1A and 1B) and increased the number of yeast cells that survive hydrogen peroxide treatment by more than 100-fold ( Figure 1C) .","[3.0, 3.0, 2.0, 1.0]",Biology,test,2.25,news,http://www.techtimes.com/articles/62479/20150622/fake-fasting-diet-slow-down-aging-effective-for-lab-rats-effective-for-humans.htm 10.1083/jcb.201804028,Biology_49,"And thanks to their newly-developed in vitro approach, in future it will be possible to identify other proteins that operate in the fusion process.","These findings strongly suggest that solely the R-SNA RE Ykt6 is required on autophagosomes for fusion, whereas the R-SNA RE Sec22 is dispensable during the autophagosome-vacuole fusion process.","These results help to understand autophagy and its underlying molecular processes better. And thanks to their newly-developed in vitro approach, in future it will be possible to identify other proteins that operate in the fusion process. Note: material may have been edited for length and content.","Whereas vam3Δsec22ts mutant autophagosomes fused normally with vacuoles at restrictive temperature, vam3Δykt6ts autophagosomes displayed substantially reduced fusion independent of the nature of the vacuolar and cytosolic fractions (Fig. These findings strongly suggest that solely the R-SNA RE Ykt6 is required on autophagosomes for fusion, whereas the R-SNA RE Sec22 is dispensable during the autophagosome-vacuole fusion process. Taken together, our findings reveal that autophagosome-vacuole fusion requires the action of the Q-SNA REs Vam3, Vam7, and Vti1 on the vacuole and the R-SNA RE Ykt6 on the autophagosome.","[3.0, 1.0, 1.0, 1.0]",Biology,test,1.5,news,http://ct.moreover.com/?a=34819790734&p=1pl&v=1&x=8aQKBEotEoZ2dQYDB6dLKA 10.1111/ddi.12244,Biology_500,"Many species groups are affected by this issue, and modeling at finder spatial scales can only partially mitigate that, the researchers say.",The projected future convergence of priority sites for narrow-and wide-ranging amphibians may therefore echo historical processes underlying contemporary biodiversity patterns.,"That's the finding of a case study focusing on amphibians in Africa, are large number of which are on the brink of extinction. Many species groups are affected by this issue, and modeling at finder spatial scales can only partially mitigate that, the researchers say. Of those, 400 had too few existing records to allow modeling their distribution on continental scales.","These patterns are consistent with the theory that long-term climatic stability, combined with topographic complexity and geographic isolation, gives rise to, and may continue supporting, high rates of rarity and endemism . The projected future convergence of priority sites for narrow-and wide-ranging amphibians may therefore echo historical processes underlying contemporary biodiversity patterns. The 1°resolution used here is, however, too coarse to capture the variations in local climate, biotic interaction and adaptive potential that are ultimately central to species persistence under climate change .","[2.0, 4.0, 2.0, 2.0]",Biology,test,2.5,news,http://www.techtimes.com/articles/14993/20140905/threatened-amphibians-are-invisible-under-climate-change-models.htm 10.1098/rspb.2014.0298,Biology_507,"This is because nature allows for more years for growing, and because larger animals can better withstand times without food or water, and because they become more difficult to bring down by predators as they grow larger.","This suggests that being crepuscular is a poor strategy for volant species, perhaps because they are exposed to both diurnal and nocturnal predators, resulting in higher extrinsic mortality.","This is because nature allows for more years for growing, and because larger animals can better withstand times without food or water, and because they become more difficult to bring down by predators as they grow larger. In this new effort, the team in Ireland has found that there are some glaring exceptions to this rule--animals that can fly or that live in trees or in burrows live longer than other animals of the same approximate size without such benefits. On the surface, it seems pretty clear why.","Activity period was important in volant species, with crepuscular species possessing the shortest lifespans. This suggests that being crepuscular is a poor strategy for volant species, perhaps because they are exposed to both diurnal and nocturnal predators, resulting in higher extrinsic mortality. The scarcity of crepuscular volant species (n ¼ 16) in our dataset also suggests that specialization to be active between nocturnal and diurnal periods is a relatively unsuccessful strategy.","[1.0, 3.0, 2.0, 2.0]",Biology,test,2.0,news,http://www.technology.org/2014/04/17/study-shows-exception-rule-lifespan-fliers-burrowers-tree-dwellers/ 10.1098/rsbl.2018.0484,Biology_51,The authors of the dolphin study raised similar concerns.,"Increases in ship noise, both within and below the dolphins' call bandwidth, resulted in higher dolphin whistle frequencies and a reduction in whistle contour complexity, an acoustic feature associated with individual identification.","The team suggests that more research would help determine if these sounds increased the stress levels of the affected humpbacks. The authors of the dolphin study raised similar concerns. ""These whistles are really important,"" Bailey said in the statement.","Elevated ambient noise levels were mainly caused by ship noise. Increases in ship noise, both within and below the dolphins' call bandwidth, resulted in higher dolphin whistle frequencies and a reduction in whistle contour complexity, an acoustic feature associated with individual identification. Consequently, the noiseinduced simplification of dolphin whistles may reduce the information content in these acoustic signals and decrease effective communication, parent -offspring proximity or group cohesion.","[2.0, 2.0, 1.0]",Biology,test,1.6666666666666667,news,http://ct.moreover.com/?a=37506312271&p=1pl&v=1&x=tVLYFtj8zqmMByb4LTmdbQ 10.1098/rstb.2018.0272,Biology_52,"However, those individuals who are not displaced during an HRE may be at higher risk because standard measures to combat mosquito breeding (such as removing pools of stagnant water) are neglected when fewer people remain in the area.","Stagnant water left over from HREs leads to increased abundance of mosquitoes in affected regions, while the deterioration of public and private health regimes increases the likelihood that people are infected.","When people opt to leave the area, it reduces the number of local infections, while potentially increasing the number of infections elsewhere. However, those individuals who are not displaced during an HRE may be at higher risk because standard measures to combat mosquito breeding (such as removing pools of stagnant water) are neglected when fewer people remain in the area. And as people move into a disaster area to offer emergency relief -- or when they return after the event -- the number of local infections rises.","The resulting flooding led to the displacement and death of many individuals. Stagnant water left over from HREs leads to increased abundance of mosquitoes in affected regions, while the deterioration of public and private health regimes increases the likelihood that people are infected. While forecasting the extent and impact of HRE-induced epidemics is challenging, well designed and parametrized mathematical models can be used to simulate the potential trajectory and severity of outbreaks, as well as the impact of control interventions.","[4.0, 4.0, 2.0, 2.0]",Biology,test,3.0,news,http://ct.moreover.com/?a=39454767451&p=1pl&v=1&x=t_1mmmyJBvTAz09R9w2bgA 10.1016/j.psyneuen.2015.02.021,Biology_520,I wonder if we'll look back at the keyhole pout and experience similar skepticism.,"Estradiol may increase blood flow to blood vessels close to the surface of the skin, increasing skin redness .","To me, the keyhole pout seems like another blip on the timeline of women mutilating their bodies to adhere to our society's bizarre beauty standards. I wonder if we'll look back at the keyhole pout and experience similar skepticism. It's a small hole, but ample enough for the average gnat.","For example, female rhesus macaques' ) and mandrills' facial skin becomes redder during the fertile phase of their ovarian cycles, complementing findings for similar changes in the color of female hindquarter skin also become darker during the fertile phase of their ovarian cycles ( . Estradiol may increase blood flow to blood vessels close to the surface of the skin, increasing skin redness . For example, increasing red, yellow, and light skin coloration increases the perceived health of white European and black African women's faces Re et al., 2011) .","[1.0, 1.0, 1.0, 1.0]",Biology,test,1.0,news,http://ct.moreover.com/?a=40110965820&p=1pl&v=1&x=Qx0hryJzolGQFttyX4iJKw 10.1890/130352,Biology_523,"This matches very closely with our new approach to protecting the Hudson's tidal habitats.""",Dealing with rapid or unanticipated change may mean doing some things differently.,"""For example, the authors appeal for conservation organizations to start evaluating over what time period their investments in habitat protection are likely to provide conservation benefits. We must recognize that if you are in for the long term--as most conservation organizations expect to be--you are going to have to ensure that the investments you make today align with the conditions you expect for the future. This matches very closely with our new approach to protecting the Hudson's tidal habitats.""","If the organization is starting conservation planning ""from scratch"", a more general conservation planning guide or resource will be of greater use (eg . Dealing with rapid or unanticipated change may mean doing some things differently. This may require trying things out, learning what works well and what does not, and then sharing those lessons with others.","[5.0, 1.0, 2.0, 1.0, 1.0]",Biology,test,1.0,news,http://www.sciencedaily.com/releases/2015/03/150302105334.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29 10.1126/scitranslmed.aaa2406,Biology_524,Gecko Biomedical will be testing the glue product in humans later this year.,"With our catheter-based device, an elastic biodegradable adhesive can provide adequate tissue fixation that is amenable to healing and growing tissues, for instance, in the pediatric population.","Further studies will reveal the appropriate lengths of time for different circumstances. Gecko Biomedical will be testing the glue product in humans later this year. ""Our collaboration across hospitals and institutions to find new and minimally invasive applications for this glue in clinical settings is a great multi-disciplinary example,"" Karp said.","For interfacing with the clinic, the entire procedure can be visualized and monitored with two-and three-dimensional ultrasound or endoscopic guidance. With our catheter-based device, an elastic biodegradable adhesive can provide adequate tissue fixation that is amenable to healing and growing tissues, for instance, in the pediatric population. The device remains in the body for less than 5 min, and no long-term adverse device-related complications were seen in preliminary in vivo testing in rodents (100% survival rate).","[3.0, 3.0, 1.0, 2.0, 1.0]",Biology,test,2.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/xKAN1BWH9mM/ 10.1186/s13287-015-0250-7,Biology_53,"Flow cytometry analysis demonstrated that EC-MSCs expressed CD90, CD105, and CD73, while being negative for the leukocyte common antigen CD45.","EC-MSCs showed high expression for CD90 (96.3 %), moderate expression for CD105 (64.31 %), and low expression for CD73 (23.09 %) while were negative for the leukocyte common antigen CD45.","Differentiation assays proved that EC-MSCs are able to differentiate towards mesodermal lineages (osteogenic, adipogenic, chondrogenic). Flow cytometry analysis demonstrated that EC-MSCs expressed CD90, CD105, and CD73, while being negative for the leukocyte common antigen CD45. Immunofluorescence analysis showed a high percentage of positive cells for OCT-4 and SSEA-1.","Actually, while the differentiated cells die within two days after death, the MSCs reside in their hypoxic tissue niche in a state of quiescence or dormancy, and survive by adapting to a low rate of oxygen consumption with a slow Fig. EC-MSCs showed high expression for CD90 (96.3 %), moderate expression for CD105 (64.31 %), and low expression for CD73 (23.09 %) while were negative for the leukocyte common antigen CD45. Consistently, anoxia and a lack of nutrients participate in the positive selection of more robust and undifferentiated stem cells .","[4.0, 4.0, 4.0]",Biology,test,4.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/6X1w7O2uQ6Y/ 10.1016/j.immuni.2014.08.009,Biology_542,"But if it does, future vaccines could try to mimic the effect of bacteria to prompt a bigger immune response.",We found fewer TIV-specific IgG + ASCs and lower serum IgG in antibiotic-treated mice at day 5 after boost injection (Figures 3G and 3H) .,"He cautions that the group would need to expose the mice to flu after vaccination to confirm that bacterial signals influence the vaccine-induced resistance to the virus. But if it does, future vaccines could try to mimic the effect of bacteria to prompt a bigger immune response. The results also raise questions about the role of antibiotics in vaccine response, says Paul Thomas, an immunologist at St. Jude Children's Research Hospital in Memphis, Tennessee.",These results suggest that TLR5 signaling plays an important role in differentiation or function of memory B cells following vaccination with TIV. We found fewer TIV-specific IgG + ASCs and lower serum IgG in antibiotic-treated mice at day 5 after boost injection (Figures 3G and 3H) . A pairwise analysis between the corresponding serum ELISA and B cell ELISPOT samples revealed a positive correlation between the frequency of ASCs and the magnitude of TIV-specific IgG antibodies in the serum (Figure 3I ).,"[2.0, 3.0, 3.0, 3.0, 2.0]",Biology,test,2.6,news,http://news.sciencemag.org/biology/2014/09/gut-bugs-may-boost-flu-shots-effects 10.1038/s41598-017-02200-6,Biology_546,Eso no quiere decir que las frutas y los vegetales no sean fuente de nutrientes saludables.,There was no difference in indices of fecal community richness and diversity (α-diversity indices) throughout the intervention period (Supplementary Fig.,"El cuerpo humano si alberga quimicos daninos y metabolitos, pero el higado y otros sistemas defensivos hacen un gran trabajo removiendolos. Eso no quiere decir que las frutas y los vegetales no sean fuente de nutrientes saludables. Pero lo que la mayoria de personas no sabe es que los antioxidantes pueden volverse oxidantes, o moleculas daninas, si se consumen en exceso.","Linear regression analysis of data from this study showed a significant positive correlation with day 4 body weight and Firmicutes proportion (p = 0.006), and a negative correlation with Bacteroidetes (p = 0.011) ( Supplementary Fig. There was no difference in indices of fecal community richness and diversity (α-diversity indices) throughout the intervention period (Supplementary Fig. 2 ; p = 0.49).","[1.0, 1.0, 1.0]",Biology,test,1.0,news,http://ct.moreover.com/?a=32614260924&p=1pl&v=1&x=x58kqB1gETBD4UaE29QL7w 10.1038/s41558-018-0138-5,Biology_552,"Mais en fin de compte, les proprietaires sont eux-memes responsables des fondations : les frais de reparation peuvent s'elever jusqu'a 100.000 euros.","These earlier onsets also lead to increases in aridity in these regions of up to 20 mm in summer, when snowmelt is no longer a source of water.","<< Ces 83 municipalites ne sont que la partie emergee de l'iceberg >>, declare le directeur Dick de Jong du KCAF. Mais en fin de compte, les proprietaires sont eux-memes responsables des fondations : les frais de reparation peuvent s'elever jusqu'a 100.000 euros. (c) Fournis par GMGroup Les scientifiques l'ont vu venir L'annee derniere, des scientifiques nous ont mis en garde contre les consequences de longues periodes de secheresse.","Earlier onsets of snowmelt cause increases in the available soil water in the winter and spring for all of the warming levels in the Alpine North and Boreal regions (Fig. These earlier onsets also lead to increases in aridity in these regions of up to 20 mm in summer, when snowmelt is no longer a source of water. Global warming leads to significant intensification of European droughts, which confirms previous work .","[1.0, 1.0, 1.0, 1.0, 1.0]",Biology,test,1.0,news,http://ct.moreover.com/?a=38642705313&p=1pl&v=1&x=pZFPPvjcPbqWY6U9r6YODg 10.1038/nclimate3115,Biology_556,"It will take significant cuts in greenhouse gas emissions within 15 years, plus efforts to recapture some of the carbon that's already been emitted, perhaps by planting new forests.","However, the consistency of negative global yield impacts of increasing temperature quantified here at the global level should not be applied to the local or regional scale.","But they may have to move to higher and cooler latitudes, or farther up a mountainside. It will take significant cuts in greenhouse gas emissions within 15 years, plus efforts to recapture some of the carbon that's already been emitted, perhaps by planting new forests. Globally, though, wheat may not be in short supply in a warmer world.","Therefore, applying multi-method ensembles can improve reliability of the assessment of climate impacts on global food security. However, the consistency of negative global yield impacts of increasing temperature quantified here at the global level should not be applied to the local or regional scale. As previous studies have found, there were considerable large variations of increasing temperature impacts on wheat yields at the local and regional scale , and the spatial variation of temperature impacts has also been observed in the two modelling approaches here among different locations.","[1.0, 4.0, 1.0, 2.0]",Biology,test,2.0,news,http://ct.moreover.com/?a=37496373362&p=1pl&v=1&x=oDbPw9Zwcd-hgZts33YaUQ 10.1038/s41467-019-09921-4,Biology_558,"[Contact: Dawn Levy, (865) 576-6448; levyd@ornl.gov] Image: https://www.ornl.gov/sites/default/files/2019-05/Materials-Engineering_heat_transport_0.png Caption: In a perfect thermoelectric crystal, vibrational waves decompose and localize.","As is evident, increasing temperature shrinks the available phase space for scattering, which explains the anomalous sharpening of the LA linewidths.","The discovery improves understanding of thermoelectric performance and may enable unconventional heat transport in future materials. [Contact: Dawn Levy, (865) 576-6448; levyd@ornl.gov] Image: https://www.ornl.gov/sites/default/files/2019-05/Materials-Engineering_heat_transport_0.png Caption: In a perfect thermoelectric crystal, vibrational waves decompose and localize. A diagram of simulated phonon energy versus momentum reveals exactly where heat transport stops because of vibrations interfering nonlinearly--the flat band between the curved top and V-shaped bottom bands.","The phase space for this type of scattering is the surface shown in Fig. As is evident, increasing temperature shrinks the available phase space for scattering, which explains the anomalous sharpening of the LA linewidths. 1 ) suggests a transition in the anharmonic dynamics.","[2.0, 1.0, 1.0, 1.0, 1.0]",Biology,test,1.2,news,http://ct.moreover.com/?a=39376795900&p=1pl&v=1&x=MbBcpHsYAT6RSwtgQIFUoA 10.1007/s00394-017-1546-4,Biology_562,"Most of the salt in the American diet comes from processed packaged foods and restaurant meals, so do more of your own cooking using whole foods, and you'll make it easier for the gut bugs to keep your blood pressure numbers from boiling over.",There was a significant increase in diet-associated-diversity that was unique to the animal-based diet.,"Now, this doesn't mean they don't work; it's just that you shouldn't fall back on popping pills as your only source of probiotics. Go Easy on Salt It's okay to spike your water bottle with some salt to replenish sweat losses, but for the sake of your microbiome, don't treat the salt shaker like a hammer. Most of the salt in the American diet comes from processed packaged foods and restaurant meals, so do more of your own cooking using whole foods, and you'll make it easier for the gut bugs to keep your blood pressure numbers from boiling over.","Elevated DCA concentrations may have contributed to microbial disturbances in the animal-based diet, as this bile acid can inhibit the growth of members of the Bacteroidetes and Firmicutes phyla. There was a significant increase in diet-associated-diversity that was unique to the animal-based diet. This effect was reversed 2 days after this diet ended.","[1.0, 3.0, 1.0, 2.0, 2.0]",Biology,test,1.8,news,http://ct.moreover.com/?a=37668175479&p=1pl&v=1&x=_T71-ZM2wwBhLL-NxT1lBA 10.1016/j.str.2011.12.009,Biology_589,"As scientists reverse engineer phages, he suggests, they can isolate those parts that are most effective at killing bacteria and perhaps produce a new class of antibacterial agents.","Structure of Membrane-Piercing Spike polypeptide chains, which are about to be folded, in register; and it provides an increased stability to the tip structure once the protein has folded.","But the discovery of the sharp iron needle, he says, suggests that P2 and Ph92 don't need any help. Leiman notes that findings like these could lead to new ways to combat bacteria that make people sick. As scientists reverse engineer phages, he suggests, they can isolate those parts that are most effective at killing bacteria and perhaps produce a new class of antibacterial agents.","The iron ion is likely to have a dual function: it participates in the folding of gpV into a trimer by helping to keep the three Structure of Membrane-Piercing Spike polypeptide chains, which are about to be folded, in register; and it provides an increased stability to the tip structure once the protein has folded. Both phages P2 and f92 require calcium for infection.","[1.0, 1.0, 3.0]",Biology,test,1.0,news,http://news.sciencemag.org/2012/02/bacteria-killing-viruses-wield-iron-spike 10.1038/ncomms4974,Biology_600,"""We were able to show that perfectly prepared materials actually have the properties that have been theoretically predicted.""","However, typically the highest spin polarizations of Heusler compounds obtained by this method amount to 60-70% at low temperatures 15 , with a single exception of 83-89% at 2 K, which collapses to C50% at room temperature 16 However, it is not clear, whether the predicted high magnetoresistance effects were not seen because the materials are contrary to predictions not half-metals or owing to the tunnel junction properties.","""It is not merely a breakthrough in the search for new spintronic materials but also in the interplay between theory and experiment,"" remarked Jourdan. ""We were able to show that perfectly prepared materials actually have the properties that have been theoretically predicted."" ""Such a combination of electronic structure and theoretical photoemission calculations made direct comparison with the corresponding experimental data possible, which in turn was essential to interpreting the 100 percent spin polarization that was measured.""","The magnetoresistance effect of planar tunnelling junctions between ferromagnetic electrodes is often related to the spin polarization by the application of the Jullière model 13 , which is justified only if the translational symmetry in the tunnelling process is completely broken. However, typically the highest spin polarizations of Heusler compounds obtained by this method amount to 60-70% at low temperatures 15 , with a single exception of 83-89% at 2 K, which collapses to C50% at room temperature 16 However, it is not clear, whether the predicted high magnetoresistance effects were not seen because the materials are contrary to predictions not half-metals or owing to the tunnel junction properties. Especially the pronounced reduction of the magnetoresistances at room temperature is surprising, because the Curie temperatures of Heusler compounds can approach 1,000 K (for example, Co 2 MnSi 20,21 ).","[3.0, 1.0, 3.0, 1.0, 1.0]",Biology,test,1.8,news,http://www.sciencedaily.com/releases/2014/06/140613084427.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29 10.1186/s40317-015-0059-2,Biology_605,"Preparing penguin, pup, or fish carcasses before consumption happens at the surface, not down below.","In addition, 397G attempted to steal a pup but was unsuccessful.","Also, the carcasses were at a depth they wouldn't normally be unless something had placed them there. Preparing penguin, pup, or fish carcasses before consumption happens at the surface, not down below. So Krause and colleagues think it's likely that the leopard seals were eating kills theyaor another leopard sealahad previously hidden away.","One of the seven Cape Shirreff CRITTERCAM records (397G) covered 3 foraging days and contained ten successful Antarctic fur seal pup captures, six of which were stolen by at least three other adult female leopard seals. In addition, 397G attempted to steal a pup but was unsuccessful. Two of the kleptoparasitic females were identified from our study population by photo ID, both of which were longer (standard length) and heavier than 397G.","[1.0, 1.0, 1.0, 1.0, 1.0]",Biology,test,1.0,news,http://news.nationalgeographic.com/2015/08/150807-leopard-seals-antarctica-behavior-ocean-animals-science 10.1210/en.2013-1955,Biology_65,"""We believe that BPA actually reprograms the stem cells to be more sensitive to estrogen throughout life, leading to a life-long increased susceptibility to diseases including cancer,"" Prins said.","As previously observed (28), progressive malignancy incidence was noted over time with highest HG-PIN and cancer incidence present at 4 months.","Prins found that a third of tissue samples taken from mice fed BPA had either pre-cancerous lesions or prostate cancer, compared to only 12 percent in a control group of mice fed oil. If the prostate stem cells were exposed to BPA before implantation and again as they produced prostate tissue in the mice, 45 percent of the tissue samples had pre-cancerous lesions or cancer. ""We believe that BPA actually reprograms the stem cells to be more sensitive to estrogen throughout life, leading to a life-long increased susceptibility to diseases including cancer,"" Prins said.","Together, these results document that levels of bioactive BPA in the present study are similar to levels found in human umbilical cord blood and newborns in the general population . As previously observed (28), progressive malignancy incidence was noted over time with highest HG-PIN and cancer incidence present at 4 months. Examples of HG-PIN and prostate adenocarcinoma as well as benign lesions of hyperplasia and SQM are shown in Fig 5 with PSA immunostaining to confirm their human origin and lack of basal cell staining to confirm carcinoma.","[2.0, 2.0, 1.0]",Biology,test,1.6666666666666667,news,http://www.healthcanal.com/cancers/46375-bpa-increases-risk-of-cancer-in-human-prostate-tissue.html 10.1073/pnas.1317120111,Biology_66,"This suggests that marine top predators are important in climate regulation, although they are mostly left out of climate models, Nevitt says.",Our results imply that marine top predators play a critical role in maintaining both ocean health and global climate.,"""The data are really striking,"" says Gabrielle Nevitt, professor of neurobiology, physiology, and behavior at the University of California, Davis, and co-author of the paper with graduate student Matthew Savoca. This suggests that marine top predators are important in climate regulation, although they are mostly left out of climate models, Nevitt says. ""In addition to studying how these marine top predators are responding to climate change, our data suggest that more attention should be focused on how ecological systems, themselves, impact climate.","This study demonstrates that dimethyl sulfide, a chemical cue involved in global climate regulation, mediates a tritrophic mutualistic interaction between marine apex predators and primary producers. Our results imply that marine top predators play a critical role in maintaining both ocean health and global climate. Our results highlight the need for more collaboration and discussion between micro-and macroscale biologists working on global issues in the Southern Ocean.","[4.0, 4.0, 4.0]",Biology,test,4.0,news,http://www.theepochtimes.com/n3/576581-scent-that-guides-seabirds-keeps-climate-cool-too/ 10.1098/rsbl.2018.0484,Biology_81,The authors of the dolphin study raised similar concerns.,The dolphin whistles had a less complex contour shape during increased ambient noise in the 2.5 and 20 kHz TOLs.,"The team suggests that more research would help determine if these sounds increased the stress levels of the affected humpbacks. The authors of the dolphin study raised similar concerns. ""These whistles are really important,"" Bailey said in the statement.","Over the entire deployment period, relatively high ambient noise levels were mainly caused by vessel noise and were above 120 dB re 1 mPa 11% of the time (electronic supplementary material, figures S4 and S5). The dolphin whistles had a less complex contour shape during increased ambient noise in the 2.5 and 20 kHz TOLs. Since these frequencies are outside the mean range of the whistles, this suggests that the signaller responded by modifying the call as opposed to the received call losing components through masking.","[1.0, 2.0, 2.0]",Biology,test,1.6666666666666667,news,http://ct.moreover.com/?a=37506312271&p=1pl&v=1&x=tVLYFtj8zqmMByb4LTmdbQ 10.1210/en.2013-1955,Biology_84,"""We believe that BPA actually reprograms the stem cells to be more sensitive to estrogen throughout life, leading to a life-long increased susceptibility to diseases including cancer,"" Prins said.","Similar to estradiol-17 (E 2 ), BPA increased stem-progenitor cell self-renewal and expression of stem-related genes in a dose-dependent manner.","""The findings of adverse effects of BPA in human tissue are highly relevant and should encourage agencies like the Food & Drug Administration to re-evaluate their policies in the near future."" The amount of BPA given to the mice was equal to the levels an average person ingests. ""We believe that BPA actually reprograms the stem cells to be more sensitive to estrogen throughout life, leading to a life-long increased susceptibility to diseases including cancer,"" Prins said.","Together, the present findings demonstrate that human prostate stem-progenitor cells are direct BPA targets and that developmental exposure to BPA at low-doses increases hormone dependent cancer risk in the human prostate epithelium. Similar to estradiol-17 (E 2 ), BPA increased stem-progenitor cell self-renewal and expression of stem-related genes in a dose-dependent manner. Further, 10 nM BPA and E 2 possessed equimolar membrane-initiated signaling with robust induction of p-Akt and p-Erk at 15 min.","[4.0, 1.0, 4.0, 3.0, 1.0]",Biology,test,3.0,news,http://www.scienceworldreport.com/articles/12081/20140110/fetal-exposure-to-chemicals-in-plastic-bottles-increases-risk-of-prostate-cancer-later-study-confirms.htm 10.1038/s41598-019-44350-9,Biology_9,"The results from this study at Marshall University demonstrate that the Na/K-ATPase oxidant amplification loop in adipocytes, or cells specialized for fat storage, when impaired, could cause adipocyte dysfunction, worsening obesity and potentially increasing the severity of related diseases.","In particular, the increases in plasma levels of leptin and inflammatory cytokines (i.e., IL-6, TNFα, and MCP1) in mice fed a WD were dramatically attenuated by NaKtide expression in adipocytes.","""I am very excited about the work in the current Scientific Reports article and the clinical relevance it presents for the role of adipocytes in obesity and other disease states,"" said Komal Sodhi, M.D., senior author, and associate professor of surgery and biomedical sciences at the Joan C. Edwards School of Medicine. The results from this study at Marshall University demonstrate that the Na/K-ATPase oxidant amplification loop in adipocytes, or cells specialized for fat storage, when impaired, could cause adipocyte dysfunction, worsening obesity and potentially increasing the severity of related diseases. The basis of the research examined more closely the role of the adipocyte in obesity, including how it impacts oxidative stress, inflammation, neurodegeneration and NASH.","Attenuation of the NKAL in the adipocytes during exposure to the WD ameliorated oxidant stress within these cells as well as the WD-induced hypertension, dyslipidemia, and insulin resistance. In particular, the increases in plasma levels of leptin and inflammatory cytokines (i.e., IL-6, TNFα, and MCP1) in mice fed a WD were dramatically attenuated by NaKtide expression in adipocytes. This suggests a central role of the Na/K-ATPase signaling loop within adipocytes in the development of obesity and systemic oxidative stress in response to a WD.","[3.0, 2.0, 2.0, 2.0, 1.0]",Biology,test,2.0,news,http://ct.moreover.com/?a=39358808843&p=1pl&v=1&x=pKbzYhsPxx5njcLIUcmXsA 10.1098/rstb.2018.0272,Biology_97,"The study, which appears in Philosophical Transactions of the Royal Society B, finds that the risk of a disease outbreak is highest if the HRE occurs early in the transmission season, or the period of time when mosquitoes are able to pass on the virus to humans.","The risk of outbreaks is highest if an HRE occurs early in the transmission season, and lowest if it occurs late in the season.","The study, which appears in Philosophical Transactions of the Royal Society B, finds that the risk of a disease outbreak is highest if the HRE occurs early in the transmission season, or the period of time when mosquitoes are able to pass on the virus to humans. According to the study, an HRE that occurs on July 1 results in 70 percent fewer disease cases compared to an HRE that occurs on June 1. ""The warmer it is, the faster an infected mosquito will be able to transmit the virus.","We found that the primary drivers of the impact of HREs on mosquito-borne infectious disease include the timing of those events relative to the transmission season, and the proportion of the population displaced during an HRE event. The risk of outbreaks is highest if an HRE occurs early in the transmission season, and lowest if it occurs late in the season. For instance, the cumulative number of cases decreases by 70% for the scenario with an HRE occurring on 1 July relative to the scenario with an HRE occurring on 1 June in the absence of population displacement.","[3.0, 4.0, 4.0, 4.0]",Biology,test,3.75,news,https://www.futurity.org/mosquito-borne-disease-rainfall-2054692-2/ 10.1038/ng.3239,Biology_tweet_105,KCNA2; ; 13868; epileptic encephalopathy.; Monoallelic; Loss of function; ,"Screening a pilot cohort of 33 patients, we identified mutations in known epilepsy-related genes in 16 cases 17 .",KCNA2; ; 13868; epileptic encephalopathy.; Monoallelic; Loss of function; ,"Therefore, potassium channel genes represent interesting candidates for neurodevelopmental disorders. Screening a pilot cohort of 33 patients, we identified mutations in known epilepsy-related genes in 16 cases 17 . We evaluated the remaining 17 cases for mutations in candidate genes (Supplementary Note), which led to the detection of a heterozygous de novo mutation in KCNA2, c.1214C>T (encoding p.Pro405Leu), affecting the highly conserved pore domain of the voltage-gated potassium channel K V 1.2 (NM_004974, CCDS827).","[3.0, 2.0, 1.0, 1.0, 1.0]",Biology,test,1.6,tweets,586177077071769600 10.1126/science.1226727,Biology_tweet_106,"New paper in Science estimates that for every mammal species in a rainforest, there are 300 arthropod species. ","Reassuringly, our wellresolved estimates of tropical arthropod species richness are of the same order of magnitude as prior estimates (table S3) , adding credence to recent estimates of tropical arthropod diversity (5, 21) .","New paper in Science estimates that for every mammal species in a rainforest, there are 300 arthropod species. ","Because this study targeted the full spectrum of arthropods, it offers a comprehensive test of previous estimates of species richness based only on selected guilds or taxa. Reassuringly, our wellresolved estimates of tropical arthropod species richness are of the same order of magnitude as prior estimates (table S3) , adding credence to recent estimates of tropical arthropod diversity (5, 21) . Although the scope for direct comparison is limited because of regional differences in sampling effort, lowland tropical forest in Panama seems to support 2.1 to 8.4 times as many arthropod species as observed in temperate forests (table S3) .","[2.0, 5.0, 3.0, 3.0]",Biology,test,3.25,tweets,279311859184721921 10.1098/rsbl.2018.0484,Biology_tweet_130, Noise levels in the world's oceans are on the rise and this new study found that dolphins are simplifying their calls to be heard over noise from recreational boats and other vessels in nearby shipping lanes #sciencenews ,The dolphin whistles had a less complex contour shape during increased ambient noise in the 2.5 and 20 kHz TOLs., Noise levels in the world's oceans are on the rise and this new study found that dolphins are simplifying their calls to be heard over noise from recreational boats and other vessels in nearby shipping lanes #sciencenews ,"Over the entire deployment period, relatively high ambient noise levels were mainly caused by vessel noise and were above 120 dB re 1 mPa 11% of the time (electronic supplementary material, figures S4 and S5). The dolphin whistles had a less complex contour shape during increased ambient noise in the 2.5 and 20 kHz TOLs. Since these frequencies are outside the mean range of the whistles, this suggests that the signaller responded by modifying the call as opposed to the received call losing components through masking.","[4.0, 4.0, 3.0, 3.0, 3.0]",Biology,test,3.4,tweets,1055179407609004033 10.1016/j.psyneuen.2015.02.021,Biology_tweet_158,"Facial colour in women tracks their estradiol levels, gives information about reproductive cycle ","Estradiol may increase blood flow to blood vessels close to the surface of the skin, increasing skin redness .","Facial colour in women tracks their estradiol levels, gives information about reproductive cycle ","For example, female rhesus macaques' ) and mandrills' facial skin becomes redder during the fertile phase of their ovarian cycles, complementing findings for similar changes in the color of female hindquarter skin also become darker during the fertile phase of their ovarian cycles ( . Estradiol may increase blood flow to blood vessels close to the surface of the skin, increasing skin redness . For example, increasing red, yellow, and light skin coloration increases the perceived health of white European and black African women's faces Re et al., 2011) .","[5.0, 3.0, 3.0]",Biology,test,3.6666666666666665,tweets,600584109551943681 10.1016/j.str.2011.12.009,Biology_tweet_176,Bacteria-Killing Viruses Wield an Iron Spike:  A Single Iron Atom On An Amino-Acid Spike:  [image],"Structure of Membrane-Piercing Spike polypeptide chains, which are about to be folded, in register; and it provides an increased stability to the tip structure once the protein has folded.",Bacteria-Killing Viruses Wield an Iron Spike:  A Single Iron Atom On An Amino-Acid Spike:  [image],"The iron ion is likely to have a dual function: it participates in the folding of gpV into a trimer by helping to keep the three Structure of Membrane-Piercing Spike polypeptide chains, which are about to be folded, in register; and it provides an increased stability to the tip structure once the protein has folded. Both phages P2 and f92 require calcium for infection.","[1.0, 3.0, 2.0]",Biology,test,2.0,tweets,173183745791238145 10.1038/s41559-019-0899-x,Biology_tweet_177,"Super happy to present our latest paper on global food webs: Years of work on predator-prey body-mass ratios and the first use of the GATEWAy data base.","Predators typically exert the strongest feeding pressure on prey that are 1-2 orders of magnitude smaller 1 , while weaker interaction strengths are realized with prey that are smaller or larger than this size 11 .","Super happy to present our latest paper on global food webs: Years of work on predator-prey body-mass ratios and the first use of the GATEWAy data base.","The varying body-mass ratios limit which trophic interactions are realized in a community , and the strength of these interactions . Predators typically exert the strongest feeding pressure on prey that are 1-2 orders of magnitude smaller 1 , while weaker interaction strengths are realized with prey that are smaller or larger than this size 11 . Moreover, they also buffer natural communities against perturbations from global warming","[4.0, 4.0, 4.0, 2.0, 3.0]",Biology,test,3.4,tweets,1130491352024850432 10.1002/sctm.16-0492,Biology_tweet_185,"Review! Wharton’s Jelly: The Rich, but Enigmatic, Source of MSCs @username @username ","They also identified three zones: amnion, Wharton's jelly and vessel walls within the cord, and showed arterial perivascular jelly of about 650 microns depth before and after digestion.","Review! Wharton’s Jelly: The Rich, but Enigmatic, Source of MSCs @username @username ","specifically distinguished between in situ umbilical cord stromal stem cells (isUCSSC) and cultured UCSSC. They also identified three zones: amnion, Wharton's jelly and vessel walls within the cord, and showed arterial perivascular jelly of about 650 microns depth before and after digestion. Indeed, Farias et al.","[3.0, 4.0, 2.0, 3.0, 2.0]",Biology,test,2.8,tweets,862852350205100035 10.1126/scitranslmed.aap8307,Biology_tweet_197,"Metarrestin, an inhibitor of tumor metastasis, discovered thru team science @ KU, @username, @username, and @username and more. Congrats to first author Kevin Frankowski and special thanks to Udo Rudloff, Juan Maruguan, and Sui Huang. ",Evaluation of apoptotic index showed less than 1% of cells undergoing apoptosis in response to metarrestin treatment.,"Metarrestin, an inhibitor of tumor metastasis, discovered thru team science @ KU, @username, @username, and @username and more. Congrats to first author Kevin Frankowski and special thanks to Udo Rudloff, Juan Maruguan, and Sui Huang. ",S9C ). Evaluation of apoptotic index showed less than 1% of cells undergoing apoptosis in response to metarrestin treatment. Selective inhibition of Pol II by -amanitin induces a localization shift to the cytoplasm except for PNClocalized CUGBP ( fig.,"[4.0, 5.0, 4.0, 5.0, 3.0]",Biology,test,4.2,tweets,996824817880977408 10.1038/ncomms4974,Biology_tweet_198,Material of the future: Breakthrough for information technology based on Heusler materials ,"However, typically the highest spin polarizations of Heusler compounds obtained by this method amount to 60-70% at low temperatures 15 , with a single exception of 83-89% at 2 K, which collapses to C50% at room temperature 16 However, it is not clear, whether the predicted high magnetoresistance effects were not seen because the materials are contrary to predictions not half-metals or owing to the tunnel junction properties.",Material of the future: Breakthrough for information technology based on Heusler materials ,"The magnetoresistance effect of planar tunnelling junctions between ferromagnetic electrodes is often related to the spin polarization by the application of the Jullière model 13 , which is justified only if the translational symmetry in the tunnelling process is completely broken. However, typically the highest spin polarizations of Heusler compounds obtained by this method amount to 60-70% at low temperatures 15 , with a single exception of 83-89% at 2 K, which collapses to C50% at room temperature 16 However, it is not clear, whether the predicted high magnetoresistance effects were not seen because the materials are contrary to predictions not half-metals or owing to the tunnel junction properties. Especially the pronounced reduction of the magnetoresistances at room temperature is surprising, because the Curie temperatures of Heusler compounds can approach 1,000 K (for example, Co 2 MnSi 20,21 ).","[2.0, 3.0, 4.0, 3.0]",Biology,test,3.0,tweets,476748536064000000 10.1126/sciadv.aat6509,Biology_tweet_20,This is quite interesting. The 2005 hurricane season resulted in the maximum number of storms that the Atlantic could produce (under current climate conditions) ,"By estimating both the mean number of tropical cyclones and their possible year-to-year random variability, we find that the likelihood that the maximum number of storms in the Atlantic could be greater than the number of events observed during the 2005 season is less than 3.5%.",This is quite interesting. The 2005 hurricane season resulted in the maximum number of storms that the Atlantic could produce (under current climate conditions) ,"By estimating both the mean number of tropical cyclones and their possible year-to-year random variability, we find that the likelihood that the maximum number of storms in the Atlantic could be greater than the number of events observed during the 2005 season is less than 3.5%. Using a less restrictive comparison between simulated and observed climate with the internal variability accounted for, this probability increases to 9%; however, the estimated maximum possible number of tropical cyclones does not greatly exceed the 2005 total. Hence, the 2005 season can be used as a risk management benchmark for the maximum possible number of tropical cyclones in the Atlantic.","[3.0, 4.0, 3.0, 4.0]",Biology,test,3.5,tweets,1032390725885865984 10.1073/pnas.1317120111,Biology_tweet_203,Cool paper on a 'tritrophic mutualism'- phytoplankton attract seabirds to eat primary consumers ,Our results imply that marine top predators play a critical role in maintaining both ocean health and global climate.,Cool paper on a 'tritrophic mutualism'- phytoplankton attract seabirds to eat primary consumers ,"This study demonstrates that dimethyl sulfide, a chemical cue involved in global climate regulation, mediates a tritrophic mutualistic interaction between marine apex predators and primary producers. Our results imply that marine top predators play a critical role in maintaining both ocean health and global climate. Our results highlight the need for more collaboration and discussion between micro-and macroscale biologists working on global issues in the Southern Ocean.","[3.0, 1.0, 3.0, 2.0, 3.0]",Biology,test,2.4,tweets,446948274420056064 10.1007/s10142-018-0639-3,Biology_tweet_207,"Happy to see out our first articles using the @username reference sequence ","We found an average of 1.97 K-motifs, 0.87 Y-motifs, and 0.73 S-motifs per dehydrin in the wheat genome.","Happy to see out our first articles using the @username reference sequence ","The dehydrin gene family was of particular interest given its known role in the drought response and the differential expression of these genes in our RNA-Seq analyses. We found an average of 1.97 K-motifs, 0.87 Y-motifs, and 0.73 S-motifs per dehydrin in the wheat genome. The dehydrin genes were clustered on chromosomes 5 and 6 (37 of 50 mapped), with 28 dehydrin genes (46.7%) located on the long arm of group 6 chromosomes (6L).","[2.0, 4.0, 1.0, 1.0]",Biology,test,1.0,tweets,1101217465793724416 10.1098/rsbl.2018.0484,Biology_tweet_21,Noise levels in the world's oceans are on the rise and this new study found that dolphins are simplifying their cal ,"Consequently, the noiseinduced simplification of dolphin whistles may reduce the information content in these acoustic signals and decrease effective communication, parent -offspring proximity or group cohesion.",Noise levels in the world's oceans are on the rise and this new study found that dolphins are simplifying their cal ,"Increases in ship noise, both within and below the dolphins' call bandwidth, resulted in higher dolphin whistle frequencies and a reduction in whistle contour complexity, an acoustic feature associated with individual identification. Consequently, the noiseinduced simplification of dolphin whistles may reduce the information content in these acoustic signals and decrease effective communication, parent -offspring proximity or group cohesion. Vocal adjustments may compensate for increased ambient noise, but there may be constraints that limit this ability or ecological consequences to modified signals.","[4.0, 4.0, 3.0, 3.0]",Biology,test,3.5,tweets,1055251384210083840 10.1038/ng.3239,Biology_tweet_215,KCNA2 can cause epileptic encephalopathies after gain-of-function or loss-of-function mutations ,"Comparing the allele frequency of the 6 KCNA2 nonsynonymous variants in our validation cohorts (6/(354 × 2); excluding the first mutation encoding p.Pro405Leu detected in the discovery cohort of 33 patients) with those of missense and nonsense variants reported in the largest available control database (ExAC; 144/122,828) showed a significant enrichment of KCNA2 variants in our patient cohorts using Fisher's exact test (P = 2.6 × 10 −4 ).",KCNA2 can cause epileptic encephalopathies after gain-of-function or loss-of-function mutations ,"Similarly, patient 7 carrying the de novo mutation c.890G>A (encoding p.Arg297Gln) presented with a more severe phenotype consisting of moderate intellectual disability, moderate to severe ataxia and pharmacoresistant seizures. Comparing the allele frequency of the 6 KCNA2 nonsynonymous variants in our validation cohorts (6/(354 × 2); excluding the first mutation encoding p.Pro405Leu detected in the discovery cohort of 33 patients) with those of missense and nonsense variants reported in the largest available control database (ExAC; 144/122,828) showed a significant enrichment of KCNA2 variants in our patient cohorts using Fisher's exact test (P = 2.6 × 10 −4 ). Further statistical evidence is provided in the Supplementary Note.","[4.0, 3.0, 3.0, 3.0]",Biology,test,3.25,tweets,575257385675042817 10.1016/j.cub.2013.05.047,Biology_tweet_225,"Viviparous lizards can have dramatically different lives, depending on their first meal. ",We show that this single meal had an overall and long-lasting impact.,"Viviparous lizards can have dramatically different lives, depending on their first meal. ","However, environmental variations of weak intensity and short duration could be of major importance when they influence key targets or critical stages. We show that this single meal had an overall and long-lasting impact. Effects on dispersal arose within 10 days, and we found effects 1-2 months later on growth, recapture probability, and juvenile survival.","[3.0, 1.0, 4.0]",Biology,test,3.0,tweets,519476054893674496 10.1038/nclimate3115,Biology_tweet_230,1 °C global temperature increase: global wheat yield projected to decline between 4.1% and 6.4% @username,"However, the consistency of negative global yield impacts of increasing temperature quantified here at the global level should not be applied to the local or regional scale.",1 °C global temperature increase: global wheat yield projected to decline between 4.1% and 6.4% @username,"Therefore, applying multi-method ensembles can improve reliability of the assessment of climate impacts on global food security. However, the consistency of negative global yield impacts of increasing temperature quantified here at the global level should not be applied to the local or regional scale. As previous studies have found, there were considerable large variations of increasing temperature impacts on wheat yields at the local and regional scale , and the spatial variation of temperature impacts has also been observed in the two modelling approaches here among different locations.","[3.0, 2.0, 3.0]",Biology,test,2.6666666666666665,tweets,781419463803559937 10.1126/scitranslmed.aal2774,Biology_tweet_231,A time to heal - circadian fibroblast mobilization during wound healing ,"This is consistent with the migratory capacity of cells, adjacent to a nascent wound, being determined by the actin dynamical state at the circadian phase when the wound is incurred.",A time to heal - circadian fibroblast mobilization during wound healing ,"The timedependent difference in F-actin polarization was sustained for at least the first 9 hours of healing. This is consistent with the migratory capacity of cells, adjacent to a nascent wound, being determined by the actin dynamical state at the circadian phase when the wound is incurred. Accordingly, continuous recording of cellular impedance in PER2::LUC cultures revealed a CRY-dependent circadian oscillation, with greatest adhesion in phase with PER2 expression (Fig.","[2.0, 3.0, 4.0]",Biology,test,3.0,tweets,928358483057094656 10.1038/s41467-018-07175-0,Biology_tweet_232,"Hormones keep on surprising us. Wonderful collaborative effort from the lab shows that estrogen receptor signaling in the breast epithelium is much more complex than we previously thought. Time to revisit some of our models! #BriskenLab #EPFL @username ","In contrast to the present finding that ERαAF-1 0 mammary epithelia fail to develop alveoli, some of the ERαNeoKO epithelial grafts grew during pregnancy and developed alveoli .","Hormones keep on surprising us. Wonderful collaborative effort from the lab shows that estrogen receptor signaling in the breast epithelium is much more complex than we previously thought. Time to revisit some of our models! #BriskenLab #EPFL @username ","In addition to changes in the levels of the ligands the concomitant loss of PgR expression, which opposes many ERα actions may have a role to play. In contrast to the present finding that ERαAF-1 0 mammary epithelia fail to develop alveoli, some of the ERαNeoKO epithelial grafts grew during pregnancy and developed alveoli . It is conceivable that complete loss of ERα function in some MECs accounts for this; the activity of the resulting E1 ERα variant protein in the ERαNeoKO mice is animal and celltype dependent .","[2.0, 1.0, 4.0]",Biology,test,2.0,tweets,1061153324391694337 10.1038/s41598-019-44350-9,Biology_tweet_234,Now you know. The central regulator of diet induced #obesity revealed @username ,Our results showed increases in plasma leptin concentrations in mice fed a WD.,Now you know. The central regulator of diet induced #obesity revealed @username ,Treatment with the lenti-adiponectin-GFP-NaKtide ameliorated the increases in the plasma concentrations of these inflammatory cytokines. Our results showed increases in plasma leptin concentrations in mice fed a WD. This was attenuated by treatment with lenti-adiponectin-GFP-NaKtide ( Fig.,"[1.0, 1.0, 1.0, 1.0]",Biology,test,1.0,tweets,1133303440183107584 10.1038/s41467-019-08813-x,Biology_tweet_237,"Today in @username a graphene transfer approach using paraffin as a support layer to obtain wrinkle-reduced, clean, large-area graphene retaining high mobility ","Similar to previous reports, our PMMA-transferred CVD monolayer graphene on Si/SiO 2 substrate experienced compressive strain and p-doping 30 .","Today in @username a graphene transfer approach using paraffin as a support layer to obtain wrinkle-reduced, clean, large-area graphene retaining high mobility ","In Fig. Similar to previous reports, our PMMA-transferred CVD monolayer graphene on Si/SiO 2 substrate experienced compressive strain and p-doping 30 . In contrast, our paraffin-transferred CVD monolayer graphene on Si/SiO 2 substrate experienced almost zero strain and very weak p-doping, approaching that of intrinsic graphene (Fig.","[3.0, 1.0, 1.0, 4.0]",Biology,test,1.0,tweets,1098182125436760064 10.1038/s41467-019-09455-9,Biology_tweet_25,A gut microbiome signature for cirrhosis due to nonalcoholic fatty liver dise... - Caussy C et al. - #microbiome,This study leverages from a unique and well-characterized cohort including participants with NAFLD-cirrhosis which allows studying the specific gutmicrobiome signature of this extreme and well-defined clinical phenotype.,A gut microbiome signature for cirrhosis due to nonalcoholic fatty liver dise... - Caussy C et al. - #microbiome,"Hence, this conveniently assessed microbial biomarker could present an adjunct tool to current invasive approaches to determine stage of liver disease. This study leverages from a unique and well-characterized cohort including participants with NAFLD-cirrhosis which allows studying the specific gutmicrobiome signature of this extreme and well-defined clinical phenotype. The fundamental difference between the previous study and the present study is the clinical context of use of the gut-microbiome signature.","[3.0, 5.0, 3.0, 4.0]",Biology,test,3.75,tweets,1112257101324267520 10.1016/j.immuni.2014.08.009,Biology_tweet_255,Gut microbiota promote antibody responses to seasonal flu vaccine. Pulendran lab. ,We found fewer TIV-specific IgG + ASCs and lower serum IgG in antibiotic-treated mice at day 5 after boost injection (Figures 3G and 3H) .,Gut microbiota promote antibody responses to seasonal flu vaccine. Pulendran lab. ,These results suggest that TLR5 signaling plays an important role in differentiation or function of memory B cells following vaccination with TIV. We found fewer TIV-specific IgG + ASCs and lower serum IgG in antibiotic-treated mice at day 5 after boost injection (Figures 3G and 3H) . A pairwise analysis between the corresponding serum ELISA and B cell ELISPOT samples revealed a positive correlation between the frequency of ASCs and the magnitude of TIV-specific IgG antibodies in the serum (Figure 3I ).,"[3.0, 4.0, 2.0, 2.0, 1.0]",Biology,test,2.4,tweets,510221646071074816 10.1016/j.cmet.2015.05.012,Biology_tweet_289,RT jimmy23352550: RT HopefulGeek: RT allentien: Scientific evidence and thought indicates #IntermittentFasting ben… ,These concerns point to the need for dietary interventions that induce PF-like effects while minimizing the risk of adverse effects and the burden of complete food restriction.,RT jimmy23352550: RT HopefulGeek: RT allentien: Scientific evidence and thought indicates #IntermittentFasting ben… ,"In humans, IF and less-severe regimens (e.g., consumption of approximately 500 kcal/day for 2 days a week) have beneficial effects on insulin, glucose, C-reactive protein, and blood pressure . These concerns point to the need for dietary interventions that induce PF-like effects while minimizing the risk of adverse effects and the burden of complete food restriction. PF cycles extended both medium and maximum chronological lifespan (Figures 1A and 1B) and increased the number of yeast cells that survive hydrogen peroxide treatment by more than 100-fold ( Figure 1C) .","[2.0, 2.0, 3.0]",Biology,test,2.333333333333333,tweets,690714631556431872 10.1007/s00125-018-4778-9,Biology_tweet_41,"#Type2diabetes is associated with decline in verbal memory and fluency, but the effect of #diabetes on brain atrophy may begin earlier @username @username #dementia #brainhealth ","The effects of type 2 diabetes and poor metabolic health at midlife, and the impact of accrual of cerebrovascular lesions at older age, both deserve further study to inform preventative efforts against dementia.","#Type2diabetes is associated with decline in verbal memory and fluency, but the effect of #diabetes on brain atrophy may begin earlier @username @username #dementia #brainhealth ","Strengths of our study include longitudinal measurement of a wide range of cognitive tests covering different cognitive domains in conjunction with serial brain MRI scans. Conclusion and area for future research In this study, type 2 diabetes was associated with decline in verbal memory and fluency in older community-dwelling people without dementia over a period of~5 years but not with MRI markers of brain atrophy. The effects of type 2 diabetes and poor metabolic health at midlife, and the impact of accrual of cerebrovascular lesions at older age, both deserve further study to inform preventative efforts against dementia.","[1.0, 3.0, 2.0, 4.0]",Biology,test,2.5,tweets,1073517957572059136 10.1073/pnas.1815660115,Biology_tweet_42,A strain of mycoplasma promotes lymphomagenesis in an in vivo mouse model and its DnaK protein is likely implicated in the transformation process at @username ,"Eight animals were injected with nonviable mycoplasma, and none developed lymphoma up to 28 wk of age (see also Materials and Methods).",A strain of mycoplasma promotes lymphomagenesis in an in vivo mouse model and its DnaK protein is likely implicated in the transformation process at @username ,"Seven animals died of wasting within 30 wk after infection, and none of the remaining animals developed lymphoma. Eight animals were injected with nonviable mycoplasma, and none developed lymphoma up to 28 wk of age (see also Materials and Methods). Uninfected spleens showed very little variation in size and were considered as references in comparing the size of spleen from infected animals.","[3.0, 2.0, 4.0, 3.0, 2.0]",Biology,test,2.8,tweets,1070073024987234304 10.1098/rspb.2014.2335,Biology_tweet_57,Host&pathogen ecology drive seasonal dynamics of white-nose syndrome in bats. Another top paper here: ,"Increases in infectiousness as the fungus grows on hibernating bats may drive winter transmission, with loads increasing throughout the winter.",Host&pathogen ecology drive seasonal dynamics of white-nose syndrome in bats. Another top paper here: ,"If contact with an environmental reservoir drives transmission, then prevalence would be predicted to increase significantly as bats contact infected environments. Increases in infectiousness as the fungus grows on hibernating bats may drive winter transmission, with loads increasing throughout the winter. Phenology varies by latitude; bats in southern sites have shorter hibernation seasons, swarm later in the autumn and return to maternity colonies earlier .","[5.0, 3.0, 4.0, 3.0]",Biology,test,3.75,tweets,540141133662527488 10.1016/j.celrep.2018.06.099,Biology_tweet_95,"Competitive reorganization of category-selective visual cortex following ""severe anatomical perturbation"" (resection of right occipitotemporal cortex) — with intact cognitive and high-level visual function #plasticity Liu et al. in @username: ","In category-selective visual cortices, however, object-and sceneselective regions in the intact left hemisphere were stable early on, but regions subserving face and word recognition emerged later and evinced competition for cortical representation.","Competitive reorganization of category-selective visual cortex following ""severe anatomical perturbation"" (resection of right occipitotemporal cortex) — with intact cognitive and high-level visual function #plasticity Liu et al. in @username: ","showed age-appropriate intellectual performance and visuoperceptual face and object recognition skills. In category-selective visual cortices, however, object-and sceneselective regions in the intact left hemisphere were stable early on, but regions subserving face and word recognition emerged later and evinced competition for cortical representation. These findings reveal alterations in the selectivity and topography of category-selective regions when confined to a single hemisphere and provide insights into dynamic functional changes in extrastriate cortical architecture.","[4.0, 2.0, 2.0, 2.0]",Biology,test,2.5,tweets,1024354073582002176 10.1186/s13287-015-0250-7,Biology_easy_13,"Surprisingly, in absence of any stimuli, some adherent cells closely resembling neuronal and glial morphology were also observed.","Surprisingly, in absence of any stimuli, some adherent cells closely resembling neuronal and glial morphology were also observed.","Immunofluorescence analysis showed a high percentage of positive cells for OCT-4 and SSEA-1. Surprisingly, in absence of any stimuli, some adherent cells closely resembling neuronal and glial morphology were also observed. Interestingly, our results revealed that approximately 15 % of the cell populations were TUJ-1 positive, whereas GFAP expression was detected in only a few cells.","Immunofluorescence analysis showed a high percentage of positive cells for OCT-4 and SSEA-1. Surprisingly, in absence of any stimuli, some adherent cells closely resembling neuronal and glial morphology were also observed. Interestingly, our results revealed that approximately 15 % of the cell populations were TUJ-1 positive, whereas GFAP expression was detected in only a few cells.",[5],Biology,test,5.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/6X1w7O2uQ6Y/ 10.1186/s13287-015-0250-7,Biology_easy_25,"Furthermore, TEM analysis confirmed the stemness of EC-MSCs and identified some cells with a typical neuronal morphology.","Furthermore, TEM analysis confirmed the stemness of EC-MSCs and identified some cells with a typical neuronal morphology.","Interestingly, our results revealed that approximately 15 % of the cell populations were TUJ-1 positive, whereas GFAP expression was detected in only a few cells. Furthermore, TEM analysis confirmed the stemness of EC-MSCs and identified some cells with a typical neuronal morphology. CONCLUSIONS: Our findings raise the prospect that the tissues harvested from equine ligaments up to 72 hours of post-mortem represent an available reservoir of specific stem cells.","Interestingly, our results revealed that approximately 15 % of the cell populations were TUJ-1 positive, whereas GFAP expression was detected in only a few cells. Furthermore, TEM analysis confirmed the stemness of EC-MSCs and identified some cells with a typical neuronal morphology. Additionally, it is associated with pneumopericardium in the donor horse secondary to a sternal bone marrow aspiration .",[5],Biology,test,5.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/6X1w7O2uQ6Y/ 10.1186/s13287-015-0250-7,Biology_easy_29,"Interestingly, our results revealed that approximately 15 % of the cell populations were TUJ-1 positive, whereas GFAP expression was detected in only a few cells.","Interestingly, our results revealed that approximately 15 % of the cell populations were TUJ-1 positive, whereas GFAP expression was detected in only a few cells.","Surprisingly, in absence of any stimuli, some adherent cells closely resembling neuronal and glial morphology were also observed. Interestingly, our results revealed that approximately 15 % of the cell populations were TUJ-1 positive, whereas GFAP expression was detected in only a few cells. Furthermore, TEM analysis confirmed the stemness of EC-MSCs and identified some cells with a typical neuronal morphology.","Surprisingly, in absence of any stimuli, some adherent cells closely resembling neuronal and glial morphology were also observed. Interestingly, our results revealed that approximately 15 % of the cell populations were TUJ-1 positive, whereas GFAP expression was detected in only a few cells. Furthermore, TEM analysis confirmed the stemness of EC-MSCs and identified some cells with a typical neuronal morphology.",[5],Biology,test,5.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/6X1w7O2uQ6Y/ 10.1186/s13287-015-0250-7,Biology_easy_37,"Interestingly, our results revealed that approximately 15 % of the cell populations were TUJ-1 positive, whereas GFAP expression was detected in only a few cells.","Surprisingly, in our cell culture conditions, in the absence of any kind of differentiation stimuli, some cells derived from EC-MSCs displayed a typical neuronal and glial-like morphology.","Surprisingly, in absence of any stimuli, some adherent cells closely resembling neuronal and glial morphology were also observed. Interestingly, our results revealed that approximately 15 % of the cell populations were TUJ-1 positive, whereas GFAP expression was detected in only a few cells. Furthermore, TEM analysis confirmed the stemness of EC-MSCs and identified some cells with a typical neuronal morphology.","These findings confirm that a high percentage of EC-MSCs are naive and undifferentiated sharing ancestral or primitive characteristics . Surprisingly, in our cell culture conditions, in the absence of any kind of differentiation stimuli, some cells derived from EC-MSCs displayed a typical neuronal and glial-like morphology. Interestingly, immunofluorescence analysis confirmed our observations under phase contrast microscopy, showing that approximately 15 % of the cell populations were TUJ-1-positive with a fibrillar cytoplasmic staining among the cells displaying neuronal-like morphology, whereas the GFAP expression was detected in both the cytoplasm and the cytoplasmic extensions of only a few cells.",[1],Biology,test,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/6X1w7O2uQ6Y/ 10.1038/ng.3239,Biology_easy_38,"The researchers discovered that the mutations disrupt the ion channel's function either by cutting the flow of potassium, leading to a loss of function; or by increasing potassium flow, leading to an excess gain of function.",Coexpression of Pro405Leu or Ile263Thr and wild-type channel led to a significant reduction in the current amplitude in comparison to expression of wild-type channel alone (indicated by an asterisk).,"The researchers discovered that the mutations disrupt the ion channel's function either by cutting the flow of potassium, leading to a loss of function; or by increasing potassium flow, leading to an excess gain of function. Patients demonstrating a loss of function had their first epileptic seizures starting at the age of around one, but the attacks ceased during childhood or in the patient's teenage years. For patients with increased function, however, epileptic seizures began even earlier and recurred into adulthood.","A dominant-negative effect of the Pro405Leu and Ile263Thr mutants on wild-type K V 1.2 was seen when a constant amount of cRNA for the wild-type channel (amount 1 in b) was injected with either water or increasing amounts of cRNA for the mutant channels (top: Pro405Leu: ratio 1:1, n = 47; ratio 1:2, n = 40; ratio 1:4, n = 36; bottom: Ile263Thr: ratio 1:1, n = 34; ratio 1:2, n = 42; ratio 1:4, n = 38). Coexpression of Pro405Leu or Ile263Thr and wild-type channel led to a significant reduction in the current amplitude in comparison to expression of wild-type channel alone (indicated by an asterisk). Groups were statistically different (one-way ANOVA, P < 0.001; post-hoc Dunn's method, P < 0.05).",[1],Biology,test,1.0,news,http://www.sciencedaily.com/releases/2015/03/150311081755.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29 10.1038/ng.3239,Biology_easy_44,This treatment is to be applied.,Clinical genetic studies and correlation with functional investigations from additional patients with further mutations are needed to confirm this genotypephenotype relationship.,"For patients whose potassium flows are too high, there is an immediate treatment option in the form of 4-aminopyridine, an approved drug which specifically blocks the relevant ion channel. This treatment is to be applied. The researchers and doctors hope it will lead to a reduction of seizures and improve mental abilities.",This may suggest that different pathomechanisms underlie distinctive clinical symptoms. Clinical genetic studies and correlation with functional investigations from additional patients with further mutations are needed to confirm this genotypephenotype relationship. The panel used to screen the pilot cohort of 33 patients (including the index patient) comprised 485 known and putative epilepsy-related genes (Supplementary Table 1) .,[1],Biology,test,1.0,news,http://www.sciencedaily.com/releases/2015/03/150311081755.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29 10.1038/ng.3239,Biology_easy_54,"The fact that both excessive opening or entire blockage of the K v 1.2 channel can lead to epilepsy, corroborate the hypothesis that a very fine balance of potassium levels seems to be essential for proper brain functioning.","Four individuals presented with febrile and multiple afebrile, often focal seizure types, multifocal epileptiform discharges strongly activated by sleep, mild to moderate intellectual disability, delayed speech development and sometimes ataxia.","""What astonished us however, is that some patients carried mutations that caused the channel to always stay open. The fact that both excessive opening or entire blockage of the K v 1.2 channel can lead to epilepsy, corroborate the hypothesis that a very fine balance of potassium levels seems to be essential for proper brain functioning. According to Patrick May, these findings also underline the importance of Systems Biomedicine approaches.","Using next-generation sequencing, we identified four different de novo mutations in KCNA2, encoding the potassium channel K V 1.2, in six isolated patients with epileptic encephalopathy (one mutation recurred three times independently). Four individuals presented with febrile and multiple afebrile, often focal seizure types, multifocal epileptiform discharges strongly activated by sleep, mild to moderate intellectual disability, delayed speech development and sometimes ataxia. Functional studies of the two mutations associated with this phenotype showed almost complete loss of function with a dominant-negative effect.",[1],Biology,test,1.0,news,http://www.healthcanal.com/genetics-birth-defects/61151-lcsb-researchers-help-discover-new-epilepsy-gene.html 10.3168/jds.2015-10517,Biology_easy_74,"Breeders can now use diagnostic tests for the APAF1 mutation to avoid mating two carriers while still retaining the beneficial genetic contributions derived from Chief, which are estimated to be about $30 billion in increased milk production.","For example, the milk produced as a result of a successful pregnancy and the number of complete gestations in a cow's lifetime are essential to maintaining the profitability of a modern dairy operation.","A single midterm abortion could cost a dairy about $800. Breeders can now use diagnostic tests for the APAF1 mutation to avoid mating two carriers while still retaining the beneficial genetic contributions derived from Chief, which are estimated to be about $30 billion in increased milk production. Just as rapid, low-cost genotyping revolutionized dairy cattle breeding, so too will whole-genome sequencing be used to increase the accuracy of sire and dam selection,"" Lewin says.","We thus propose that the APAF1 p.Q579X nonsense mutation is the functional equivalent of the Apaf1 knockout. For example, the milk produced as a result of a successful pregnancy and the number of complete gestations in a cow's lifetime are essential to maintaining the profitability of a modern dairy operation. If reproductive performance decreases, financial losses accrue because of reduced milk production of the herd and the need for replacement animals to maintain herd size.",[1],Biology,test,1.0,news,http://www.futurity.org/pawnee-farm-arlinda-chief-cows-1273492-2/ 10.1038/s41559-019-0899-x,Biology_easy_78,"The prediction is even more precise if, in addition to body mass, additional features such as the mode of locomotion or the metabolic type are considered.","On average, interactions between relatively large predator and prey species are characterized by higher body-mass ratios than interactions between smaller species.","With the help of the data they had collected, Brose and his team were able to predict precisely which animals play a key role within a food web. The prediction is even more precise if, in addition to body mass, additional features such as the mode of locomotion or the metabolic type are considered. The analysis showed that, depending on the nature of the habitat, different species of predator maintain the equilibrium of an ecosystem.","This suggests that the body-mass ratios between predators and their prey increase with the masses of prey and predators (that is, the distance between the regression line and the dashed diagonal indicating equally sized predator-prey pairs). On average, interactions between relatively large predator and prey species are characterized by higher body-mass ratios than interactions between smaller species. The Bayesian approach also allowed us to fit mixed-effects models to the data, particularly the random effects on the intercept of the different studies (database variable, link.citation; see Supplementary Table GATEWAy metadata).",[1],Biology,test,1.0,news,http://ct.moreover.com/?a=39271353921&p=1pl&v=1&x=B7TN33xQfGdJisQOcwCwJw 10.3168/jds.2015-10517,Biology_easy_82,"""We are very confident that the APAF1 stop-gain mutation is the cause of fertility loss in Chief's lineage,"" Lewin says.","These estimates correspond to approximately 140,000 spontaneous abortions in the United States and 525,000 worldwide over a 35-yr period, the approximate time that Chief alleles appeared on both sides of the pedigree.","The severely shortened APAF1 peptide has the effect of making the genes inoperative because the critical piece is in the truncated portion. ""We are very confident that the APAF1 stop-gain mutation is the cause of fertility loss in Chief's lineage,"" Lewin says. A single midterm abortion could cost a dairy about $800.","Globally, the estimate is 15,000/yr based on a population size of 30 million. These estimates correspond to approximately 140,000 spontaneous abortions in the United States and 525,000 worldwide over a 35-yr period, the approximate time that Chief alleles appeared on both sides of the pedigree. Carrier frequency in US Holsteins exceeded 0.08 during the 1980s and 1990s but decreased to about 0.03 in 2010 .",[1],Biology,test,1.0,news,http://www.futurity.org/pawnee-farm-arlinda-chief-cows-1273492-2/ 10.1038/s41559-019-0899-x,Biology_easy_83,"These data enable researchers to determine the structure and stability of a habitat, without the need for a comprehensive examination of the relationships to other organisms.","This discrepancy arises because there is no unidirectional causal relationship between the two variables and because both have measurement errors of the same magnitude, which renders major axis regression the appropriate tool for analysing these data 31 .","The special feature of the method is that only limited information is needed about the characteristics of 'predators' that hunt prey animals. These data enable researchers to determine the structure and stability of a habitat, without the need for a comprehensive examination of the relationships to other organisms. The scientists were able to confirm the value of their method using a large dataset of 220,000 interactions from 290 food webs.","Ordinary least-squares (OLS) regressions relating these two variables generate different slopes depending on which variable is chosen as the independent variable (Fig. This discrepancy arises because there is no unidirectional causal relationship between the two variables and because both have measurement errors of the same magnitude, which renders major axis regression the appropriate tool for analysing these data 31 . The major axis regression showed that the overall allometric scaling relationship between predator and prey body mass was superlinear, exhibiting a slope higher than unity (Fig.",[1],Biology,test,1.0,news,http://ct.moreover.com/?a=39271353921&p=1pl&v=1&x=B7TN33xQfGdJisQOcwCwJw 10.1186/s13287-015-0250-7,Biology_easy_88,"Furthermore, TEM analysis confirmed the stemness of EC-MSCs and identified some cells with a typical neuronal morphology.","In addition, tight junctions were observed between these cells (Fig.","Interestingly, our results revealed that approximately 15 % of the cell populations were TUJ-1 positive, whereas GFAP expression was detected in only a few cells. Furthermore, TEM analysis confirmed the stemness of EC-MSCs and identified some cells with a typical neuronal morphology. CONCLUSIONS: Our findings raise the prospect that the tissues harvested from equine ligaments up to 72 hours of post-mortem represent an available reservoir of specific stem cells.","5c) were present in cytoplasm. In addition, tight junctions were observed between these cells (Fig. However, some cells at P3 and P20 appeared to have outgrowing extensions (Fig.",[1],Biology,test,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/6X1w7O2uQ6Y/ 10.1016/j.immuni.2017.07.015,Biology_easy_97,"When Chisolm and Weinmann tested embryonic stem cells, they found that one-third of the genes that were alpha-ketoglutarate-inducible in the embryonic stem cells were associated with the locations of alpha-ketoglutarate-inducible CTCF binding peaks in Th1 cells.","In part, this is due to a similar complement of transcription factors playing dual roles regulating both the gene expression programs associated with differentiation and specific metabolic pathways .","One interesting thing they noticed was that a subset of the genome binding sites for CTCF after alpha-ketoglutarate stimulation of T helper 1 (Th1) cells were associated with genes that were known to be expressed early in development, including in embryonic stem cells. When Chisolm and Weinmann tested embryonic stem cells, they found that one-third of the genes that were alpha-ketoglutarate-inducible in the embryonic stem cells were associated with the locations of alpha-ketoglutarate-inducible CTCF binding peaks in Th1 cells. Thus, control sites used during embryo growth were also likely being used to control T cell changes after an immune challenge.","The data collectively support a mechanism wherein CTCF serves to translate aKG-sensitive metabolic changes into context-dependent differentiation gene programs. In part, this is due to a similar complement of transcription factors playing dual roles regulating both the gene expression programs associated with differentiation and specific metabolic pathways . Metabolic reprogramming in ES cells plays a role in broadly regulating epigenetic states through the ability of metabolites to serve as donors and substrates for DNA and histone modifications, as well as co-factors for epigenetic-modifying complexes .",[1],Biology,test,1.0,news,http://healthmedicinet.com/news/how-a-nutrient-glutamine-can-control-gene-programs-in-cells/ 10.1186/s13287-015-0250-7,Biology_easy_98,"Surprisingly, in absence of any stimuli, some adherent cells closely resembling neuronal and glial morphology were also observed.","Differentiation assays, flow cytometry, immunofluorescence and TEM analyses confirmed the stemness of these cells.","Immunofluorescence analysis showed a high percentage of positive cells for OCT-4 and SSEA-1. Surprisingly, in absence of any stimuli, some adherent cells closely resembling neuronal and glial morphology were also observed. Interestingly, our results revealed that approximately 15 % of the cell populations were TUJ-1 positive, whereas GFAP expression was detected in only a few cells.","This study demonstrated that a viable stem cell population can be isolated and expanded from equine cadaver ligaments up to 72 hours post-mortem. Differentiation assays, flow cytometry, immunofluorescence and TEM analyses confirmed the stemness of these cells. Our research may benefit the development of an advantageous source of stem cells for regenerative medicine and cell therapy technologies.",[1],Biology,test,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/6X1w7O2uQ6Y/ 10.1038/s41559-019-0899-x,Biology_easy_102,"The scientists were able to confirm the value of their method using a large dataset of 220,000 interactions from 290 food webs.","The varying body-mass ratios limit which trophic interactions are realized in a community , and the strength of these interactions .","These data enable researchers to determine the structure and stability of a habitat, without the need for a comprehensive examination of the relationships to other organisms. The scientists were able to confirm the value of their method using a large dataset of 220,000 interactions from 290 food webs. ""If there is a big difference, this has a positive effect on the equilibrium of the energy flows of the food web and, by extension, on the stability of the ecosystem.""","The varying body-mass ratios limit which trophic interactions are realized in a community , and the strength of these interactions . Predators typically exert the strongest feeding pressure on prey that are 1-2 orders of magnitude smaller 1 , while weaker interaction strengths are realized with prey that are smaller or larger than this size 11 . Moreover, they also buffer natural communities against perturbations from global warming",[1],Biology,test,1.0,news,http://ct.moreover.com/?a=39271353921&p=1pl&v=1&x=B7TN33xQfGdJisQOcwCwJw 10.1038/s41598-019-44350-9,Biology_easy_126,"""Our data clearly suggests that obesity and the Na/K-ATPase oxidant amplification loop plays a role in neurodegeneration,"" said first author Rebecca Pratt, a Ph.D. candidate in the department of biomedical research at Marshall University.","Such changes were also observed in previous reports, even in a mouse strain which did not gain excessive amounts of weight 3 .","The researchers were able to successfully demonstrate through decreased adiposity and an improved metabolic profile the therapeutic potential of targeting NaKtide to the adipocytes. ""Our data clearly suggests that obesity and the Na/K-ATPase oxidant amplification loop plays a role in neurodegeneration,"" said first author Rebecca Pratt, a Ph.D. candidate in the department of biomedical research at Marshall University. ""Even targeting NaKtide to adipocytes alone still showed a whole-body effect, which highlights the much larger role that adipocytes play in obesity and whole body homeostasis.""","Specifically, animals given the WD demonstrated marked reductions in activity level and calculated energy expenditure. Such changes were also observed in previous reports, even in a mouse strain which did not gain excessive amounts of weight 3 . We found that these behavioral changes were strongly associated with changes in brain D2 receptor expression and tyrosine hydroxylase expression, confirmed through both immunofluorescence and western blot.",[1],Biology,test,1.0,news,http://ct.moreover.com/?a=39358808843&p=1pl&v=1&x=pKbzYhsPxx5njcLIUcmXsA 10.1098/rsbl.2018.0484,Biology_easy_129,"Well, they adapt, by simplifying their complex calls so they can better understand each other over the fray.","Consequently, the noiseinduced simplification of dolphin whistles may reduce the information content in these acoustic signals and decrease effective communication, parent -offspring proximity or group cohesion.","Well, they adapt, by simplifying their complex calls so they can better understand each other over the fray. ""Dolphins simplified their calls to counter the masking effects of vessel noise."" In the noisiest parts of the ocean, dolphins simplified their whistles and made them higher-frequency and more piercing--the dolphin equivalent of shortening their message while shouting it.","Increases in ship noise, both within and below the dolphins' call bandwidth, resulted in higher dolphin whistle frequencies and a reduction in whistle contour complexity, an acoustic feature associated with individual identification. Consequently, the noiseinduced simplification of dolphin whistles may reduce the information content in these acoustic signals and decrease effective communication, parent -offspring proximity or group cohesion. Vocal adjustments may compensate for increased ambient noise, but there may be constraints that limit this ability or ecological consequences to modified signals.",[1],Biology,test,1.0,news,http://ct.moreover.com/?a=37496201686&p=1pl&v=1&x=cTwtDfCjxcV6OlUnSzYNzw 10.1186/1472-6785-14-23,Biology_easy_156,"When the creosote was a new addition to the diet of individual N.bryanti woodrats, they had different reactions.","The effective gene number with greater expression in N. bryanti was 20.7, whereas the effective gene number for N. lepida was 14.4.","We expected a huge list of genes -- instead we found very few."" When the creosote was a new addition to the diet of individual N.bryanti woodrats, they had different reactions. They exhibited signs of severe stress, showing that because they hadn't been exposed to the diet, the genes to detoxify it hadn't been switched on.","The effective gene numbers also reflect this pattern. The effective gene number with greater expression in N. bryanti was 20.7, whereas the effective gene number for N. lepida was 14.4. In experienced N. bryanti, transcripts with the greatest expression were related to conjugation of metabolites with glucuronic acid (different glucuronosyltransferases) followed by those related to conjugation with glutathione (glutathione S-transferases; Table 5 ).",[1],Biology,test,1.0,news,http://www.sciencedaily.com/releases/2014/08/140815102324.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29 10.3168/jds.2015-10517,Biology_easy_158,The team found no animals with APAF1 from both parents among the 758 animals tested.,"Among all animals within the validation set, 246 unique haplotypes existed within the HH1 interval, as well as 323 heterozygous haplotype combinations.","But if it inherits copies of the mutation from both parents, the combination is fatal. The team found no animals with APAF1 from both parents among the 758 animals tested. Commercial testing of more than 246,000 Holsteins showed the same results.","These haplotypes are much shorter and different than those originally defined by the 75-marker window (derived from the 54,001 chip) spanning 7.1 Mbp that was used to find HH1. Among all animals within the validation set, 246 unique haplotypes existed within the HH1 interval, as well as 323 heterozygous haplotype combinations. Additionally, animals possessing ""haplotype 32"" (n = 11) had a small region of 40 markers in a 1-Mb region within the HH1 interval that was expected to be equivalent to haplotype 12 because haplotype 32 is a recombinant haplotype.",[1],Biology,test,1.0,news,http://www.futurity.org/pawnee-farm-arlinda-chief-cows-1273492-2/ 10.1038/ng.3239,Biology_easy_180,"""Kv1.2 channels efficiently repolarize a nerve cell following an action potential.",The panel used to screen the pilot cohort of 33 patients (including the index patient) comprised 485 known and putative epilepsy-related genes (Supplementary Table 1) .,"In six children, the researchers found so far unknown spontaneous mutations in the KCNA2gene that have not been present in the genome of their parents. ""Kv1.2 channels efficiently repolarize a nerve cell following an action potential. It is hence not so surprising that mutations that render this channel dysfunctional can lead to hyperexcitation of the brain.",Clinical genetic studies and correlation with functional investigations from additional patients with further mutations are needed to confirm this genotypephenotype relationship. The panel used to screen the pilot cohort of 33 patients (including the index patient) comprised 485 known and putative epilepsy-related genes (Supplementary Table 1) . The comparison of normalized peak areas for the test individual and the average of seven control individuals yields target amplicon doses indicating the copy number of the target amplicon (using the in house-developed MAQ software).,[1],Biology,test,1.0,news,http://www.healthcanal.com/genetics-birth-defects/61151-lcsb-researchers-help-discover-new-epilepsy-gene.html 10.1016/j.cub.2017.09.047,Biology_easy_244,"""It is very exciting to discover a new great ape species in the 21st century,"" he added.",We estimated the split time between populations north and south of Lake Toba at $3.4 Ma ( Figure 3B ; Table S5 ).,"""We were quite surprised that the skull was quite different in some characteristics from anything we had seen before."" ""It is very exciting to discover a new great ape species in the 21st century,"" he added. Their calculations show that the population appears to have been isolated from all other Sumatran populations for at least 10,000 to 20,000 years.","Our results supported a scenario in which orangutans from mainland Asia first entered Sundaland south of what is now Lake Toba on Sumatra, the most likely entry point based on paleogeographic reconstructions [32] . We estimated the split time between populations north and south of Lake Toba at $3.4 Ma ( Figure 3B ; Table S5 ). Under our best-fitting model, we found evidence for post-split gene flow across Lake Toba ($0.3-0.9 migrants per generation; Table S5 ), which is consistent with highly significant signatures of gene flow between P. abelii and P. tapanuliensis using D statistics (CK, BT, WA, Homo sapiens: D = À0.2819, p < 0.00001; WK, BT, LK, Homo sapiens: D = À0.2967, p < 0.00001).",[1],Biology,test,1.0,news,http://feedproxy.google.com/~r/BreakingScienceNews/~3/ePhHh7ZnOzA/tapanuli-orangutan-pongo-tapanuliensis-05389.html 10.1093/sysbio/syq054,Biology_easy_283,"This implies that for 20 million years before dinosaurs became extinct, early versions of primates also lived and evolved.","It is not clear whether a more sophisticated model would be possible to justify, and such a model is likely to introduce more uncertainty into the estimates of the divergence times, not less.","Under the new estimate, Toumai would fall within the period after the human lineage split from chimpanzees, Martin said. This implies that for 20 million years before dinosaurs became extinct, early versions of primates also lived and evolved. It challenged the accepted theory that primates and other mammals didn't really thrive on the planet until dinosaurs were gone.","The model used is relatively simple to code and understand, hopefully making our inference and assumptions transparent. It is not clear whether a more sophisticated model would be possible to justify, and such a model is likely to introduce more uncertainty into the estimates of the divergence times, not less. Most of the uncertainty in our final estimates comes from the uncertainty in results for the fossil calibrations and any uncertainty introduced by examining the model discrepancy (not shown here).",[1],Biology,test,1.0,news,http://www.usnews.com/science/articles/2010/11/08/new-statistical-model-moves-human-evolution-back-3-million-years 10.1007/s10142-018-0639-3,Biology_easy_292,"""Se ha analizado por primera vez como cambia la expresion de todos los genes del trigo en una situacion real de cultivo y en una hoja fundamental para el desarrollo del trigo (la denominada 'hoja bandera') en respuesta a unas condiciones de sequia producida en un momento muy importante para el cultivo (el llenado del grano), haciendo uso del genoma del trigo publicado el pasado agosto, ya que hemos utilizado la variedad de referencia"", anade Hernandez.","We found an average of 1.97 K-motifs, 0.87 Y-motifs, and 0.73 S-motifs per dehydrin in the wheat genome.","""Las medidas fisiologicas realizadas durante los episodios de sequia nos permiten caracterizar la respuesta del cultivo frente al estres hidrico y evaluar su adaptacion, lo que se relaciona con la activacion de redes especificas de genes"", explica Victoria Gonzalez Dugo, investigadora del Instituto de Agricultura Sostenible. ""Se ha analizado por primera vez como cambia la expresion de todos los genes del trigo en una situacion real de cultivo y en una hoja fundamental para el desarrollo del trigo (la denominada 'hoja bandera') en respuesta a unas condiciones de sequia producida en un momento muy importante para el cultivo (el llenado del grano), haciendo uso del genoma del trigo publicado el pasado agosto, ya que hemos utilizado la variedad de referencia"", anade Hernandez. La monitorizacion de las condiciones atmosfericas, del suelo y de la planta mediante sensores permite analizar estas situaciones y avanzar en el futuro.","The dehydrin gene family was of particular interest given its known role in the drought response and the differential expression of these genes in our RNA-Seq analyses. We found an average of 1.97 K-motifs, 0.87 Y-motifs, and 0.73 S-motifs per dehydrin in the wheat genome. The dehydrin genes were clustered on chromosomes 5 and 6 (37 of 50 mapped), with 28 dehydrin genes (46.7%) located on the long arm of group 6 chromosomes (6L).",[1],Biology,test,1.0,news,http://ct.moreover.com/?a=38661668947&p=1pl&v=1&x=hHjbofo7g0MdGh1zsuzYkw 10.1007/s10142-018-0639-3,Biology_easy_296,La integracion de estas tecnologias ha permitido determinar genes asociados a la calidad semolera del trigo duro y cuales de ellos se expresan de manera diferencial ante el estres hidrico en el campo de cultivo.,"We were able to identify putative regulatory TFs for 52 dehydrins, which included 228 TFs.","La monitorizacion de las condiciones atmosfericas, del suelo y de la planta mediante sensores permite analizar estas situaciones y avanzar en el futuro. En el segundo trabajo se han visto variaciones presentes en el germoplasma de trigo duro utilizado actualmente en la mejora y cuales son las mas favorables. La integracion de estas tecnologias ha permitido determinar genes asociados a la calidad semolera del trigo duro y cuales de ellos se expresan de manera diferencial ante el estres hidrico en el campo de cultivo.","A cluster of dehydrins was found as a result of the CoDReGs analysis (CoDReG 6_581_01), and it was studied in depth. We were able to identify putative regulatory TFs for 52 dehydrins, which included 228 TFs. We identified significantly enriched TF families that target dehydrins compared to all other downstream genes using χ 2 tests.",[1],Biology,test,1.0,news,http://ct.moreover.com/?a=38661668947&p=1pl&v=1&x=hHjbofo7g0MdGh1zsuzYkw 10.1098/rstb.2018.0272,Biology_easy_310,"The study, which was published in Philosophical Transactions of the Royal Society B, found that the risk of a disease outbreak is highest if the HRE occurs early in the transmission season, or the period of time when mosquitos are able to pass on the virus to humans.",The evidence from flood events elsewhere underlines the importance of the combination of conditions faced by the displaced population.,"The study, which was published in Philosophical Transactions of the Royal Society B, found that the risk of a disease outbreak is highest if the HRE occurs early in the transmission season, or the period of time when mosquitos are able to pass on the virus to humans. According to the study, an HRE that occurs on July 1 results in 70 percent fewer disease cases compared to an HRE that occurs on June 1. ""The warmer it is, the faster an infected mosquito will be able to transmit the virus.","B 374: 20180272 damming and river rerouting were a factor, other important drivers were the disruption of vector control activities and local population displacement that led to increased exposure to mosquitoes . The evidence from flood events elsewhere underlines the importance of the combination of conditions faced by the displaced population. Since human population displacement is not within the area affected by the HRE, and does not have implications for crowding, sanitation, nutrition or hygiene, it is risk-reducing.",[1],Biology,test,1.0,news,http://ct.moreover.com/?a=39454767451&p=1pl&v=1&x=t_1mmmyJBvTAz09R9w2bgA 10.1016/j.immuni.2017.07.015,Biology_easy_327,"Alpha-ketoglutarate thus appears to be responsible for part, but not all, of interleukin 2's impact on T cell gene programming.","(C and D) Circos plots for genomic regions surrounding Hlx (Chr1:184,000,000-187,200,000) and Cxcr4 (Chr1:128,800,000-131,040,000), indicating the probability for genomic interactions from the in situ Hi-C analysis.","These different concentrations of interleukin 2 signaling drive the cells to turn on different gene programs and develop gene programs similar to those from either effector or memory T cells. They found that adding permeable alpha-ketoglutarate to the low interleukin 2 condition induced about a third of the gene program induced by high interleukin 2 relative to low interleukin 2 in T cells, while it inhibited about 10 percent of the genes that were more highly expressed in low interleukin 2 relative to high interleukin 2 conditions. Alpha-ketoglutarate thus appears to be responsible for part, but not all, of interleukin 2's impact on T cell gene programming.","However, the boundary changed or the strength of interaction bias was increased in the high IL-2 Figure 4C . (C and D) Circos plots for genomic regions surrounding Hlx (Chr1:184,000,000-187,200,000) and Cxcr4 (Chr1:128,800,000-131,040,000), indicating the probability for genomic interactions from the in situ Hi-C analysis. The minimum probability of interaction shown is a p value of % 0.0001, with the increased weight of a line indicating a higher significance for the interaction (lower p value).",[1],Biology,test,1.0,news,http://healthmedicinet.com/news/how-a-nutrient-glutamine-can-control-gene-programs-in-cells/ 10.1210/en.2013-1955,Biology_easy_347,"According to the study authors, avoiding the chemical altogether is a next-to impossible feat.","In a similar manner, BPA exposure increased expression of some, but not all stemness genes with a significant increase in TBX3 and NANOG in response to 200 nM and a similar trend at 10 nM BPA (Fig 2B) .","If you're drinking from a water bottle or eating from a plastic container, chances are you're consuming it right now. According to the study authors, avoiding the chemical altogether is a next-to impossible feat. ""It's very hard to avoid.""","Exposure to 1 nM E 2 markedly increased expression of CD49f, TROP2, ABCG2, FOXM1, BMI1, TBX3, SOX2 and NANOG (Fig 2 A&B) . In a similar manner, BPA exposure increased expression of some, but not all stemness genes with a significant increase in TBX3 and NANOG in response to 200 nM and a similar trend at 10 nM BPA (Fig 2B) . Expression of epithelial cell differentiation genes NKX3.1, HOXB13, CK18 was at the lower limit of detection in day 7 prostaspheres and this was not influenced by E 2 or BPA exposure (Fig2C).",[1],Biology,test,1.0,news,http://www.medicaldaily.com/bpa-exposure-utero-may-triple-risk-prostate-cancer-can-we-do-anything-about-it-266535 10.1098/rsbl.2018.0484,Biology_easy_368,"""These whistles are really important,"" Bailey said in the statement.","Increases in ship noise, both within and below the dolphins' call bandwidth, resulted in higher dolphin whistle frequencies and a reduction in whistle contour complexity, an acoustic feature associated with individual identification.","The authors of the dolphin study raised similar concerns. ""These whistles are really important,"" Bailey said in the statement. ""Nobody wants to live in a noisy neighborhood.","Elevated ambient noise levels were mainly caused by ship noise. Increases in ship noise, both within and below the dolphins' call bandwidth, resulted in higher dolphin whistle frequencies and a reduction in whistle contour complexity, an acoustic feature associated with individual identification. Consequently, the noiseinduced simplification of dolphin whistles may reduce the information content in these acoustic signals and decrease effective communication, parent -offspring proximity or group cohesion.",[1],Biology,test,1.0,news,http://ct.moreover.com/?a=37506312271&p=1pl&v=1&x=tVLYFtj8zqmMByb4LTmdbQ 10.1186/1472-6785-14-23,Biology_easy_376,"But the new study identifies the genes switched on in two species of woodrat with resistance to the plant poisons, showing that the genes that they are born with play a central role in whether they feel the effects of its toxic chemicals.",Naïve N. bryanti had more than twice the number of GO terms that passed these criteria.,"But the new study identifies the genes switched on in two species of woodrat with resistance to the plant poisons, showing that the genes that they are born with play a central role in whether they feel the effects of its toxic chemicals. Being able to withstand the creosote bush's resin gives them exclusive access to the valuable food source in an area with little plant life. They found that when woodrats had been exposed to the creosote bush in the wild, a small number of similar genes were switched on by both species to detoxify the plant, despite having evolved the mechanisms at completely different times.","Significant Gene Ontology (GO) terms (within biological process) were different in the naïve versus experienced N. bryanti. Naïve N. bryanti had more than twice the number of GO terms that passed these criteria. The top terms related to responses to stimuli; many of the other terms related to stress, damage and cell death (Table 4A ).",[1],Biology,test,1.0,news,http://www.sciencedaily.com/releases/2014/08/140815102324.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29 10.1016/j.cub.2013.05.047,Biology_easy_424,The data show that this single meal had a significant and long-lasting impact.,We show that this single meal had an overall and long-lasting impact.,Their parents are no help to them when it comes to catching their first live insect or spider for dinner. The data show that this single meal had a significant and long-lasting impact. Lizards that had been fed were less likely to pick up and move.,"However, environmental variations of weak intensity and short duration could be of major importance when they influence key targets or critical stages. We show that this single meal had an overall and long-lasting impact. Effects on dispersal arose within 10 days, and we found effects 1-2 months later on growth, recapture probability, and juvenile survival.",[5],Biology,test,5.0,news,http://www.sciencedaily.com/releases/2013/07/130703140234.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29 10.1038/s41558-018-0298-3,Biology_easy_444,"However, it nonetheless represents a critical component of decision making that is likely to be important in successful policy development and implementation.""","However, it nonetheless represents a critical component of decision-making that is likely to be important in successful policy development and implementation.","Participants were also generally in favour of increasing product lifetimes and avoiding premature disposal, although some commented that this still wouldn't stop people from wanting new things. Professor Pidgeon concluded: ""While it is good news that the public is positive about potential changes to everyday goods, acceptability doesn't necessarily equate to levels of adoption. However, it nonetheless represents a critical component of decision making that is likely to be important in successful policy development and implementation.""","Public acceptability does not correspond directly to levels of adoption. However, it nonetheless represents a critical component of decision-making that is likely to be important in successful policy development and implementation. Integrating the findings from both the IOA modelling and deliberative workshops, we bring together different lines of evidence that can contribute to the debate surrounding the potential of resource-efficiency strategies for meeting climate mitigation goals.",[5],Biology,test,5.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/_OgH91q2U4M/ 10.1126/sciadv.1602326,Biology_easy_448,"In the presence of strong light attenuation, the solidification front initiates at the surface upon illumination and propagates toward the liquid side as the irradiation time increases.","In the presence of strong light attenuation, the solidification front initiates at the surface upon illumination and propagates toward the liquid side as the irradiation time increases.","""The technique is very simple."" In the presence of strong light attenuation, the solidification front initiates at the surface upon illumination and propagates toward the liquid side as the irradiation time increases. The researchers used poly(ethylene glycol) diacrylate in this demonstration, but the technique should work with a broad range of photocurable polymers.","The degree of bending can be controlled by adjusting the gray scale and the irradiation time, an easy approach for creating origami structures. In the presence of strong light attenuation, the solidification front initiates at the surface upon illumination and propagates toward the liquid side as the irradiation time increases. Here, we show that, without cumbersome processing steps, origami structures can be created using the FPP method with conventional photocurable polymers, and the origami process is almost spontaneous instead of a response to external stimulus.",[5],Biology,test,5.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/ANWnvA9moqY/ 10.1126/scitranslmed.aal2774,Biology_easy_451,"""This is consistent with the migratory capacity of cells, adjacent to a nascent wound, being determined by the actin dynamical state at the circadian phase when the wound is incurred,"" the authors explain.","This is consistent with the migratory capacity of cells, adjacent to a nascent wound, being determined by the actin dynamical state at the circadian phase when the wound is incurred.","When the cultures were scratched at different times, the wounds sustained in simulated 'night' conditions healed more slowly than those during the day, due to differing speeds of fibroblast response. ""This is consistent with the migratory capacity of cells, adjacent to a nascent wound, being determined by the actin dynamical state at the circadian phase when the wound is incurred,"" the authors explain. Experiments with live mice showed the same phenomenon, with the animals healing quicker if a cut was sustained during their waking hours than if it were imposed when they would ordinarily have been asleep.","The timedependent difference in F-actin polarization was sustained for at least the first 9 hours of healing. This is consistent with the migratory capacity of cells, adjacent to a nascent wound, being determined by the actin dynamical state at the circadian phase when the wound is incurred. Accordingly, continuous recording of cellular impedance in PER2::LUC cultures revealed a CRY-dependent circadian oscillation, with greatest adhesion in phase with PER2 expression (Fig.",[5],Biology,test,5.0,news,http://ct.moreover.com/?a=37732173358&p=1pl&v=1&x=_i4I4kpyZGdWx7L6J9SYVA 10.1007/s00125-018-4778-9,Biology_easy_454,"""The effects of type 2 diabetes and poor metabolic health at midlife, and the impact of accrual of cerebrovascular lesions at older age, both deserve further study to inform preventative efforts against dementia,"" the authors write.","The effects of type 2 diabetes and poor metabolic health at midlife, and the impact of accrual of cerebrovascular lesions at older age, both deserve further study to inform preventative efforts against dementia.","At baseline, individuals with diabetes had lower brain and greater ventricular volumes (b, -14.273 and b, 2.672, respectively); however, researchers found no evidence that brain atrophy occurred at a greater rate over time or mediated the diabetes-cognition relationship. ""The effects of type 2 diabetes and poor metabolic health at midlife, and the impact of accrual of cerebrovascular lesions at older age, both deserve further study to inform preventative efforts against dementia,"" the authors write. One author disclosed financial ties to the pharmaceutical industry.","Strengths of our study include longitudinal measurement of a wide range of cognitive tests covering different cognitive domains in conjunction with serial brain MRI scans. Conclusion and area for future research In this study, type 2 diabetes was associated with decline in verbal memory and fluency in older community-dwelling people without dementia over a period of~5 years but not with MRI markers of brain atrophy. The effects of type 2 diabetes and poor metabolic health at midlife, and the impact of accrual of cerebrovascular lesions at older age, both deserve further study to inform preventative efforts against dementia.",[5],Biology,test,5.0,news,http://ct.moreover.com/?a=37982778343&p=1pl&v=1&x=Tl77nywCdxBR24vsV1bOxA 10.1098/rsbl.2016.0402,Biology_easy_457,"""This finding demonstrates that humans are not unique in combining longer-term personality biases with shorter-term mood biases in judging stimuli,"" the researchers wrote on their paper.","Importantly, this finding demonstrates that humans are not unique in combining longer-term personality biases with shorterterm mood biases in judging stimuli .","As it turns out, the animal, known to be very intelligent, can be classified as glass half-full or half-empty creatures; optimism and pessimism are not exclusive to humans after all. ""This finding demonstrates that humans are not unique in combining longer-term personality biases with shorter-term mood biases in judging stimuli,"" the researchers wrote on their paper. Proactive pigs were likely to check the middle bowl, despite the certainty of the ""good outcome.""","Those living in a worse environment were more pessimistic and those in a better environment were more optimistic. Importantly, this finding demonstrates that humans are not unique in combining longer-term personality biases with shorterterm mood biases in judging stimuli . Optimistic and pessimistic responses can both be adaptive depending on the environment , allowing appropriate responses to reward or threat signals, respectively.",[5],Biology,test,5.0,news,http://www.natureworldnews.com/articles/32192/20161117/study-pigs-optimists-pessimists-occasional-mood-swings.htm 10.1126/sciadv.aas8772,Biology_easy_471,"Created in part to help the hearing and speech impaired, the new technology can be further explored for various potential applications, such as wearable IoT sensors and conformal health care devices.",Note that the huge enhance-ment of the SPL is not mainly attributed to the discrepancy in the thermal effusivity of the parylene NMs and PET films.,"Created in part to help the hearing and speech impaired, the new technology can be further explored for various potential applications, such as wearable IoT sensors and conformal health care devices. However, they tear easily and exhibit no electrical conductivity. He adds, ""These layers are capable of detecting sounds and vocal vibrations produced by the triboelectric voltage signals corresponding to sounds, which could be further explored for various potential applications, such as sound input/output devices.""","As a result, the change in the theoretical SPL as a function of the frequency for both loudspeakers exhibited agreement with our experimental results (Fig. Note that the huge enhance-ment of the SPL is not mainly attributed to the discrepancy in the thermal effusivity of the parylene NMs and PET films. The theoretical calculation of SPL reveals that the influence of thermal effusivity on the SPL is negligible for films with a nanoscale thickness, while the low thermal effusivity enhances the SPL in the case of a thick-film loudspeaker system ( fig.",[1],Biology,test,1.0,news,http://ct.moreover.com/?a=37138915959&p=1pl&v=1&x=tzxWiksba27aKX5sE_Irsw 10.1038/s41467-018-07175-0,Biology_easy_475,"For further information, please contact the cited source.","In contrast to the present finding that ERαAF-1 0 mammary epithelia fail to develop alveoli, some of the ERαNeoKO epithelial grafts grew during pregnancy and developed alveoli .","""This begs the question whether these ER-pseudo-negative breast cells will ultimately turn into estrogen receptor-positive or -negative breast cancers,"" says Cathrin Brisken. Note: material may have been edited for length and content. For further information, please contact the cited source.","In addition to changes in the levels of the ligands the concomitant loss of PgR expression, which opposes many ERα actions may have a role to play. In contrast to the present finding that ERαAF-1 0 mammary epithelia fail to develop alveoli, some of the ERαNeoKO epithelial grafts grew during pregnancy and developed alveoli . It is conceivable that complete loss of ERα function in some MECs accounts for this; the activity of the resulting E1 ERα variant protein in the ERαNeoKO mice is animal and celltype dependent .",[1],Biology,test,1.0,news,http://ct.moreover.com/?a=37666076275&p=1pl&v=1&x=HfBuTod7m05oYYtrbdPPBQ 10.1038/s41467-019-09259-x,Biology_easy_480,Scanning electron microscopy revealed that the cuticle (the outer most protective layer of the eggshell) was made up of very small spherules of minerals.,"An absence due to seasonal differences in plumage is unlikely-if these feathers are in fact a sexual characteristic, they would be expected to be present either year-round (as suggested by their presence in very young juveniles 69 ) or only present in the breeding plumage.","Despite being malformed, the egg is excellently preserved, including parts of the eggshell that are rarely seen in the fossil record, such as traces of the egg membrane and the cuticle, which are mostly made of proteins and other organic materials. Scanning electron microscopy revealed that the cuticle (the outer most protective layer of the eggshell) was made up of very small spherules of minerals. Finding this morphology in Avimaia also supports the hypothesis that a cuticle with protective spherules represents the ancestral condition for avian eggs.","It is possible the absence of RDFs in IVPP V25371 is preservational (as is the case in all described specimens lacking this feature), given that feathers are not well preserved in this specimen. An absence due to seasonal differences in plumage is unlikely-if these feathers are in fact a sexual characteristic, they would be expected to be present either year-round (as suggested by their presence in very young juveniles 69 ) or only present in the breeding plumage. Since IVPP V25371 was clearly breeding, the absence of RDFs in this specimen is most likely either a true absence or taphonomic artifact.",[1],Biology,test,1.0,news,http://ct.moreover.com/?a=38802959494&p=1pl&v=1&x=fwg4hgTtn3cRkWZQijb8rA 10.1098/rspb.2012.3017,Biology_easy_487,But the results of this study showed that even a little bit of light (20 times less than the intensity of a single street light) is enough to throw off the delicate ecological timing of reproductive maturity.,"¼ 38, z ¼ 23.28, p ¼ 0.001).","That month-long head-start is a big deal considering their entire breeding season only lasts three or four months total. But the results of this study showed that even a little bit of light (20 times less than the intensity of a single street light) is enough to throw off the delicate ecological timing of reproductive maturity. The ecological consequences of such a timing shift could thus be serious, especially as our world continues to urbanize at an increasing pace.","In addition, we detected within-treatment differences: in both treatment groups city birds started moult on average 13 days before forest birds (GLM, d.f. ¼ 38, z ¼ 23.28, p ¼ 0.001). Both control and treatment groups showed seasonal variation in the onset of morning song.",[1],Biology,test,1.0,news,http://blogs.discovermagazine.com/80beats/2013/02/14/urban-light-causes-birds-to-bloom-early/ 10.1007/s10886-015-0624-4,Biology_easy_489,"This work highlights that pollution from dirty vehicles is not only dangerous to people's health, but could also have an impact on our natural environment and the economy.""",Proboscis extension response (PER) assays showed that the alterations of the blend reduced the ability of honey bees to recognize it.,"""We don't think that air pollution from diesel vehicles is the main reason for this decline, but our latest work suggests that it may have a worse effect on the flower odors needed by bees than we initially thought. This work highlights that pollution from dirty vehicles is not only dangerous to people's health, but could also have an impact on our natural environment and the economy."" ""Our research highlights that a further stress could be the increasing amounts of vehicle emissions affecting air quality.","Exposure to diesel exhaust altered the blend of common flower volatiles significantly: myrcene was considerably reduced, β-ocimene became undetectable, and β-caryophyllene was transformed into its cis-isomer isocaryophyllene. Proboscis extension response (PER) assays showed that the alterations of the blend reduced the ability of honey bees to recognize it. The chemically reactive nitrogen oxides fraction of diesel exhaust gas was identified as capable of causing degradation of floral volatiles.",[1],Biology,test,1.0,news,http://www.futurity.org/diesel-bees-flowers-smell-1038462/ 10.1038/s41467-018-03162-7,Biology_easy_500,"""It got a lot of hype, and some criticism,"" she says.",1 Working principle of the MOF-801-based water harvesting device and adsorption isotherms.,"Last year's paper drew a great deal of attention, Wang says. ""It got a lot of hype, and some criticism,"" she says. Now, ""all of the questions that were raised from last time were explicitly demonstrated in this paper.",The use of OTTI aerogel is well- Fig. 1 Working principle of the MOF-801-based water harvesting device and adsorption isotherms. Passive radiative cooling lowers the MOF layer temperature below the ambient by dissipating thermal radiation to the clear cold sky to increase the effective RH for adsorption.,[1],Biology,test,1.0,news,http://ct.moreover.com/?a=33625727090&p=1pl&v=1&x=6DDRemXx0nYMh6Cku5XxKg 10.1038/ng.3517,Biology_easy_507,"The population of A. ipaensis was very small and isolated, and its closest relatives grew hundreds of miles to the north.",13 and 14) .,"However, what really caught their attention was that the genome of the other species, A. ipaensis, was found to be virtually identical to the B subgenome. The population of A. ipaensis was very small and isolated, and its closest relatives grew hundreds of miles to the north. ""Everything fit,"" Bertioli said.","They represent 82% and 86% of the genomes, respectively, when considering genome size estimates based on flow cytometry , or 95% and 98% of the genomes when using estimates derived from k-mer frequencies with k = 17 ( Supplementary Figs. 13 and 14) . Comparisons of the chromosomal pseudomolecules with 14 BAC sequences from A. duranensis and 6 BAC sequences from A. ipaensis showed collinearity of contigs and high sequence identity (≥99%) (Supplementary Fig.",[1],Biology,test,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/fAEZZR3EnSM/ 10.1534/genetics.113.149724,Biology_easy_543,"""This strategy is super cool and it works great,"" he says.","We observed a similarly dramatic reduction in GOA-1 protein levels in this strain ( Figure 4B , compare protein levels in lanes 3 and 4).","The advance should allow deeper insights into protein function, Chase says, ""because we can only get a true understanding of what that single protein does when we isolate its function in a living organism. ""This strategy is super cool and it works great,"" he says. ""We've already used it to tease apart some of the mechanisms of dopamine signaling, but the strategy can be adapted to study the function of any protein involved in any biological process.""","In stark contrast, when we restored NMD activity in smg-5 goa-1 animals to all cells that also expressed the tagged transgene, using an integrated untagged goa-1p::SMG-5 transgene, we found that the abundance of tagged transgene mRNA was reduced by .87% compared to goa-1p::GOA-1::let-858 mRNA levels in smg-5 goa-1 double mutants that did not express the untagged goa-1p::SMG rescue transgene ( Figure 4A , compare bars 3 and 4). We observed a similarly dramatic reduction in GOA-1 protein levels in this strain ( Figure 4B , compare protein levels in lanes 3 and 4). Indeed, expression of the untagged goa-1p::SMG-5 transgene reduced GOA-1 mRNA and protein expression to near null levels, which correlated well with null-like behaviors observed in this strain as shown in Figure 3 ( Figure 4A , compare bars 2 and 4 and protein levels in Figure 4B , lanes 2 and 4).",[1],Biology,test,1.0,news,http://www.sciencedaily.com/releases/2013/06/130619164341.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29 10.1002/sctm.16-0492,Biology_easy_544,"Their research indicates that stem cell therapy could pave the way to engineer the cells and provide a superior form of treatment, possibly using various types of cells to treat different symptoms of Parkinson's disease including memory loss and impaired movement.","They also identified three zones: amnion, Wharton's jelly and vessel walls within the cord, and showed arterial perivascular jelly of about 650 microns depth before and after digestion.","The authors of the study, Dr. Claire Henchcliffe and Malin Parmar, Ph.D., believe that the medical world is moving into a very exciting era for stem cell therapy. Their research indicates that stem cell therapy could pave the way to engineer the cells and provide a superior form of treatment, possibly using various types of cells to treat different symptoms of Parkinson's disease including memory loss and impaired movement. Thanks to massive strides in technology, the authors of this study also believe that cell replacement may hold the potential to alleviate all motor symptoms, if not more symptoms for Parkinson's disease, in the decades to come.","specifically distinguished between in situ umbilical cord stromal stem cells (isUCSSC) and cultured UCSSC. They also identified three zones: amnion, Wharton's jelly and vessel walls within the cord, and showed arterial perivascular jelly of about 650 microns depth before and after digestion. Indeed, Farias et al.",[1],Biology,test,1.0,news,http://ct.moreover.com/?a=38591955969&p=1pl&v=1&x=5Vu0GucDeixCMta6yIiyAQ 10.1083/jcb.201709137,Biology_easy_553,"IRE1 regulates the maturation of the XBP1 mRNA to produce the functional XBP1 transcription factor, which in turn bolsters the expression of target genes encoding for chaperone proteins that resolve the accumulation of misfolded proteins.","However, S729A mutation completely blocks IRE1's ability to further up-regulate XBP1s to respond to any of these ER stress conditions (Fig.","This process is especially important for B cells to respond to severe stress conditions and their ability to produce antibodies. IRE1 regulates the maturation of the XBP1 mRNA to produce the functional XBP1 transcription factor, which in turn bolsters the expression of target genes encoding for chaperone proteins that resolve the accumulation of misfolded proteins. IRE1 function is especially critical in B cells since the ER plays a central role in the biogenesis of antibodies.","Although Tg induces phosphorylation of IRE1 only at S729 in LPS-stimulated B cells, SubAB and DTT can induce phosphorylation at S729 and other sites in these cells (Fig. However, S729A mutation completely blocks IRE1's ability to further up-regulate XBP1s to respond to any of these ER stress conditions (Fig. 6) .",[1],Biology,test,1.0,news,http://ct.moreover.com/?a=33490837283&p=1pl&v=1&x=x-ALog72EnnJmdf6GZr3UA 10.1038/s41467-017-00798-9,Biology_easy_565,The implications are enormous.,"The 1 dB insertion loss bandwidth in S 21 and S 32 is 4.6 GHz (18.4%), and the S 31 isolation over this bandwidth ranges from −18.3 to −20.2 dB.","""This mm-wave circulator enables mm-wave wireless full-duplex communications,"" Krishnaswamy adds, ""and this could revolutionize emerging 5G cellular networks, wireless links for virtual reality, and automotive radar."" The implications are enormous. These radars inherently need to be full-duplex, and would work alongside ultra-sound and camera-based sensors in self-driving cars because they can work in all weather conditions and during both night and day.","T s =1/f s Fig. The 1 dB insertion loss bandwidth in S 21 and S 32 is 4.6 GHz (18.4%), and the S 31 isolation over this bandwidth ranges from −18.3 to −20.2 dB. This is notably wideband compared with prior art, including −20 dB S 31 isolation bandwidths of 4.2% in ref.",[1],Biology,test,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/gUNqEqN30k8/ 10.1038/s41467-019-08813-x,Biology_easy_569,"In experiments, the researchers' wax-coated graphene performed four times better than graphene made with a traditional polymer-protecting layer.","Similar to previous reports, our PMMA-transferred CVD monolayer graphene on Si/SiO 2 substrate experienced compressive strain and p-doping 30 .","Moreover, the coating can be washed away without leaving behind much residue. In experiments, the researchers' wax-coated graphene performed four times better than graphene made with a traditional polymer-protecting layer. ""This technology is very useful, because it solves two problems simultaneously: the wrinkles and polymer residues.""","In Fig. Similar to previous reports, our PMMA-transferred CVD monolayer graphene on Si/SiO 2 substrate experienced compressive strain and p-doping 30 . In contrast, our paraffin-transferred CVD monolayer graphene on Si/SiO 2 substrate experienced almost zero strain and very weak p-doping, approaching that of intrinsic graphene (Fig.",[1],Biology,test,1.0,news,http://news.mit.edu/2019/paraffin-wrinkles-manufacture-graphene-0306 10.1038/s41467-017-02571-4,Biology_easy_585,"A comprehensive understanding of microbial behavior in the ocean can inform human health, fisheries, and aquaculture, specifically through monitoring water quality.",8 ).,"The researchers' findings also provide insight into the conditions that more permanent organisms in the region face as the microbial plankton turnover. A comprehensive understanding of microbial behavior in the ocean can inform human health, fisheries, and aquaculture, specifically through monitoring water quality. ""This paper represents a significant advance in our knowledge of the forces that mediate community assembly in fluid environments, and provides a wealth of new information to support new hypothesis-driven research into the specific mechanisms that underpin this complex association,"" says Jack Gilbert, faculty director of the Microbiome Center at the University of Chicago, who was not involved in this work.","6B ), and also found that clustering of non-distributional OTUs results in a similar number of clusters, sharp transitions, and similar patterns of abundance ( Supplementary Fig. 8 ). We note that it will be important to keep in mind the potential effects of autocorrelation, especially when there is a large difference in autocorrelation between long and short time scales.",[1],Biology,test,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/iJfNrQxaLBI/ 10.1152/physiol.00020.2013,Biology_easy_592,"The lack of breathable oxygen, freezing cold, and these charming creatures, to name a few, but the huge amount of water pressure pressing down on you would definitely be the immediate threat.",and FIGURE 3D3) to areas of the medulla regulating cardiorespiratory behavior.,"Giphy If you somehow got stuck in the middle of an oceanic abyss, the deepest part of the ocean, you'd have a few things to worry about. The lack of breathable oxygen, freezing cold, and these charming creatures, to name a few, but the huge amount of water pressure pressing down on you would definitely be the immediate threat. Since your body's internal pressure is so much less than the ambient pressure, your lungs would not have the strength to push back against the water pressure.","We show numerous projections from these neurons (see Ref. and FIGURE 3D3) to areas of the medulla regulating cardiorespiratory behavior. These small neurons also probably have very small axons see (FIGURE 3D4); if they are below 1 m in diameter, they are beyond the resolution of the light microscope, which implies their identify must be obtained by other means.",[1],Biology,test,1.0,news,http://www.medicaldaily.com/breaking-point-how-much-water-pressure-can-human-body-take-347570 10.1038/s41586-019-0924-x,Biology_easy_593,"We hope that it will be possible in the future to target microglia subsets in harmful state.""","Overall, our results suggest that unique microglia subpopulations, characterized by distinct signatures, emerge under defined disease conditions.","""In MS patients, we managed to characterize microglia in a state that is specific for multiple sclerosis. We hope that it will be possible in the future to target microglia subsets in harmful state."" ""It is extremely exciting to see how flexible the microglia can be,"" says Prof. Prinz.","3d (Fig. Overall, our results suggest that unique microglia subpopulations, characterized by distinct signatures, emerge under defined disease conditions. Unbiased hierarchical clustering revealed four major clusters, hereafter referred to as healthy human clusters 1 to 4 (HHu-C1 to HHu-C4) (Extended Data Fig.",[1],Biology,test,1.0,news,http://ct.moreover.com/?a=38582531360&p=1pl&v=1&x=2zdS-C3YDiYNOcgSWR7vcQ 10.1177/1948550614537308,Psychology_103,"When it came to those who were sociosexually unrestricted, having casual sex was associated with higher self-esteem and life satisfaction and lower depression and anxiety.","Among low-SOI participants, those who had casual sex did not differ significantly from those who did not have casual sex on self-esteem (B ¼ À0.10, SE ¼ 0.07, p ¼ .168), depression (B ¼ 0.13, SE ¼ 0.08, p ¼ .104), or anxiety (B ¼ 0.11, SE ¼ 0.07, p ¼ .130).","By the end of the study, 42 percent of subjects reported having sex outside a relationship. When it came to those who were sociosexually unrestricted, having casual sex was associated with higher self-esteem and life satisfaction and lower depression and anxiety. ""Typically, sociosexually unrestricted individuals (i.e., those highly oriented toward casual sex) reported lower distress and higher thriving following casual sex, suggesting that high sociosexuality may both buffer against any potentially harmful consequences of casual sex and allow access to its potential benefits,"" the researchers write.","Simple slope analyses indicated that high-SOI participants who had casual sex over the academic year had higher self-esteem (B ¼ 0.14, SE ¼ 0.06, p ¼ .025) and marginally lower depression (B ¼ À0.12, SE ¼ 0.07, p ¼ .091) and anxiety (B ¼ À0.11, SE ¼ 0.06, p ¼ .086) than high-SOI participants who did not have casual sex (Figure 3) . Among low-SOI participants, those who had casual sex did not differ significantly from those who did not have casual sex on self-esteem (B ¼ À0.10, SE ¼ 0.07, p ¼ .168), depression (B ¼ 0.13, SE ¼ 0.08, p ¼ .104), or anxiety (B ¼ 0.11, SE ¼ 0.07, p ¼ .130). There were no significant three-way interactions with gender or main effects of sociosexuality or casual sex in either set of analyses.","[2.0, 2.0, 2.0, 2.0, 1.0]",Psychology,test,1.8,news,http://www.psmag.com/navigation/health-and-behavior/casual-sex-excellent-people-love-casual-sex-83847/ 10.1073/pnas.1407787111,Psychology_105,They could even see that the lags in connection development with the two task-related networks -- the frontoparietal and ventral attention networks -- were located primarily in two specific areas of the brain.,We found significant and specific maturational lag in connections within default mode network (DMN) and in DMN interconnections with two task positive networks (TPNs): frontoparietal network and ventral attention network.,"The researchers found lags in development of connection within the internally-focused network, called the default mode network or DMN, and in development of connections between DMN and two networks that process externally-focused tasks, often called task-positive networks, or TPNs. They could even see that the lags in connection development with the two task-related networks -- the frontoparietal and ventral attention networks -- were located primarily in two specific areas of the brain. The new findings mesh well with what other researchers have found by examining the physical structure of the brains of people with and without ADHD in other ways.","We found significant and specific maturational lag in connections within default mode network (DMN) and in DMN interconnections with two task positive networks (TPNs): frontoparietal network and ventral attention network. In particular, lag was observed within the midline core of the DMN, as well as in DMN connections with right lateralized prefrontal regions (in frontoparietal network) and anterior insula (in ventral attention network). Our finding of maturational lag specifically in connections within and between these networks suggests a developmental etiology for the deficits proposed in these models.","[5.0, 5.0, 5.0, 3.0]",Psychology,test,4.5,news,http://www.sciencedaily.com/releases/2014/09/140915153607.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29 10.1177/1948550614537308,Psychology_124,"""Sociosexual orientation is a relatively stable tendency toward or away from casual sex, determined by a combination of heritable factors, sociocultural learning, and past experiences, and reflected in three key components: motivation for, attitudes toward, and past experience with casual sex,"" the authors write.","Sociosexuality significantly predicted casual sex engagement after controlling for demographics, OR ¼ 2.06 [1.70, 2.49], p < .001; the interaction with gender was not significant, OR ¼ 1.13 [0.93, 1.36].","They lurk in our bar's backrooms, on our gym's racquetball courts, on cruises and in airplanes, and on every street in the city of Miami. ""Sociosexual orientation is a relatively stable tendency toward or away from casual sex, determined by a combination of heritable factors, sociocultural learning, and past experiences, and reflected in three key components: motivation for, attitudes toward, and past experience with casual sex,"" the authors write. The authors argue that there would be no reason to believe that this effect wouldn't extend to casual sex.","By the 9-month follow-up, two fifths (42%) reported at least one penetrative casual encounter over the academic year; percentages were similar in both sexes, w 2 (1) < 1. Sociosexuality significantly predicted casual sex engagement after controlling for demographics, OR ¼ 2.06 [1.70, 2.49], p < .001; the interaction with gender was not significant, OR ¼ 1.13 [0.93, 1.36]. Only 23% of those scoring below the median on sociosexuality engaged in casual sex compared to 62% of those scoring above the median, w 2 (1) ¼ 57.73, p < .001.","[5.0, 4.0, 2.0, 4.0, 3.0]",Psychology,test,3.6,news,http://www.psmag.com/navigation/health-and-behavior/casual-sex-excellent-people-love-casual-sex-83847/ 10.1073/pnas.1407787111,Psychology_132,"""It is particularly noteworthy that the networks we found to have lagging maturation in ADHD are linked to the very behaviors that are the symptoms of ADHD,"" he says.","These results suggest maturational lag of regulatory control networks contributes to inattention and/or impulsivity across different clinical populations, and they invite new research aimed at direct comparative investigation .","These networks, and the connections between them, mature throughout early childhood all the way to young adulthood. ""It is particularly noteworthy that the networks we found to have lagging maturation in ADHD are linked to the very behaviors that are the symptoms of ADHD,"" he says. ""The results of this study set the stage for the next phase of this research, which is to examine individual components of the networks that have the maturational lag,"" he says.","More broadly, our finding of lagged maturation of regulatory control networks in ADHD fits well with a previous study in juvenile offenders that found that relative immaturity of connectivity of motor planning regions with other brain regions, including DMN regions, predicted greater impulsivity . These results suggest maturational lag of regulatory control networks contributes to inattention and/or impulsivity across different clinical populations, and they invite new research aimed at direct comparative investigation . We also observed maturational lag in integration of the dmPFC and PCC ( Fig.","[1.0, 3.0, 3.0, 4.0, 3.0]",Psychology,test,2.8,news,http://www.sciencedaily.com/releases/2014/09/140915153607.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29 10.1073/pnas.1407787111,Psychology_138,"""The results of this study set the stage for the next phase of this research, which is to examine individual components of the networks that have the maturational lag,"" he says.",Our finding of maturational lag specifically in connections within and between these networks suggests a developmental etiology for the deficits proposed in these models.,"""It is particularly noteworthy that the networks we found to have lagging maturation in ADHD are linked to the very behaviors that are the symptoms of ADHD,"" he says. ""The results of this study set the stage for the next phase of this research, which is to examine individual components of the networks that have the maturational lag,"" he says. ""This study provides a coarse-grained understanding, and now we want to examine this phenomenon in a more fine-grained way that might lead us to a true biological marker, or neuromarker, for ADHD.""","In particular, lag was observed within the midline core of the DMN, as well as in DMN connections with right lateralized prefrontal regions (in frontoparietal network) and anterior insula (in ventral attention network). Our finding of maturational lag specifically in connections within and between these networks suggests a developmental etiology for the deficits proposed in these models. These advances raise possibilities for investigating maturational lag in ADHD in the developing ICN architecture of the brain (18).","[5.0, 3.0, 4.0, 4.0]",Psychology,test,4.0,news,http://www.sciencedaily.com/releases/2014/09/140915153607.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29 10.1073/pnas.1407787111,Psychology_141,Future studies of brain network maturation in ADHD could shed light into the neural basis for this difference.,Our results invite further investigation into the neurobiological mechanisms in ADHD that produce delays in development of large-scale networks.,"The findings are also relevant to thinking about the longitudinal course of ADHD from childhood to adulthood. Future studies of brain network maturation in ADHD could shed light into the neural basis for this difference. ""But without the database of fMRI images, and the spirit of collaboration that allowed them to be compiled and shared, we would never have reached this point.""",Our results provide strong initial evidence that these alterations arise from delays in typical maturational patterns. Our results invite further investigation into the neurobiological mechanisms in ADHD that produce delays in development of large-scale networks. We found significant and specific maturational lag in connections within default mode network (DMN) and in DMN interconnections with two task positive networks (TPNs): frontoparietal network and ventral attention network.,"[1.0, 5.0, 5.0, 3.0, 5.0]",Psychology,test,4.0,news,http://www.sciencedaily.com/releases/2014/09/140915153607.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29 10.1177/1948550614537308,Psychology_186,The researchers found that students who engaged in casual sex reported higher overall wellbeing.,These results integrate within a personality framework prior findings of more positive emotional reactions following casual sex among those with greater interest in or approval of casual sex and lower well-being among those who engage in it for nonautonomous reasons .,"Overall, 42 percent of the participants reported having casual sex. The researchers found that students who engaged in casual sex reported higher overall wellbeing. They also reported having less stress and better emotional health.","Typically, sociosexually unrestricted individuals (i.e., those highly oriented toward casual sex) reported lower distress and higher thriving following casual sex, suggesting that high sociosexuality may both buffer against any potentially harmful consequences of casual sex and allow access to its potential benefits. These results integrate within a personality framework prior findings of more positive emotional reactions following casual sex among those with greater interest in or approval of casual sex and lower well-being among those who engage in it for nonautonomous reasons . Consistent with theoretical perspectives and research emphasizing Anxiety p = .014 ns Figure 2 .","[4.0, 4.0, 4.0, 4.0]",Psychology,test,4.0,news,http://www.counselheal.com/articles/10249/20140626/casual-sex-can-be-good-study-reports.htm 10.1177/1948550614537308,Psychology_194,"""[P]ast findings on the main effects of casual sex on well-being range from negative to positive with a preponderance of nonsignificant results,"" the new study, led by sex researcher Zhana Vrangalova, notes.","self-congruency as critical for well-being across life domains , experienced authenticity in casual sex encounters was an independent predictor of well-being among those who engaged in it on a weekly basis, broadening the scope of influence of authenticity beyond behaviors considered universally healthy and socially desirable.","""[P]ast findings on the main effects of casual sex on well-being range from negative to positive with a preponderance of nonsignificant results,"" the new study, led by sex researcher Zhana Vrangalova, notes. In other words, the inconsistencies might mean that the true effect is context- and personality-dependent. All-negative or all-positive findings don't really account for the strange and nuanced spectrum of opinion about casual sex, and they especially exclude those who can't wait to engage in their next coital misadventure with a complete stranger they just met while grinding on a dance floor of a sweaty club.","Higher scores (1 to 5) indicate higher presence of variable. self-congruency as critical for well-being across life domains , experienced authenticity in casual sex encounters was an independent predictor of well-being among those who engaged in it on a weekly basis, broadening the scope of influence of authenticity beyond behaviors considered universally healthy and socially desirable. However, authenticity amplified, rather than mediated, the effect of sociosexuality, requiring future study.","[2.0, 2.0, 4.0, 4.0]",Psychology,test,3.0,news,http://www.psmag.com/navigation/health-and-behavior/casual-sex-excellent-people-love-casual-sex-83847/ 10.1073/pnas.1407787111,Psychology_205,Future studies of brain network maturation in ADHD could shed light into the neural basis for this difference.,Our finding of maturational lag specifically in connections within and between these networks suggests a developmental etiology for the deficits proposed in these models.,"The findings are also relevant to thinking about the longitudinal course of ADHD from childhood to adulthood. Future studies of brain network maturation in ADHD could shed light into the neural basis for this difference. ""But without the database of fMRI images, and the spirit of collaboration that allowed them to be compiled and shared, we would never have reached this point.""","In particular, lag was observed within the midline core of the DMN, as well as in DMN connections with right lateralized prefrontal regions (in frontoparietal network) and anterior insula (in ventral attention network). Our finding of maturational lag specifically in connections within and between these networks suggests a developmental etiology for the deficits proposed in these models. These advances raise possibilities for investigating maturational lag in ADHD in the developing ICN architecture of the brain (18).","[2.0, 3.0, 4.0, 2.0, 4.0]",Psychology,test,3.0,news,http://www.sciencedaily.com/releases/2014/09/140915153607.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29 10.1073/pnas.1508431112,Psychology_212,"aEURoeIt looks like musicians can take longer, more drawn out musical phrases and group them into a pattern of some kind,aEUR says Poeppel, aEURoethe response to what some people perceive as just a series of beeps and blips turns on much more sharply in musicians.aEUR Dr. Devin McAuley, a professor of cognitive science at Michigan State University who wasnaEUR(tm)t involved with the study says, aEURoeThese are exciting findings that fit into a broader body of work.","These questions cannot be answered within the scope of this study; however, we present several hypotheses to inspire future research.","However the musiciansaEUR(tm) brain waves buzzed in synchrony to music as slow as 0.7 notes per second. aEURoeIt looks like musicians can take longer, more drawn out musical phrases and group them into a pattern of some kind,aEUR says Poeppel, aEURoethe response to what some people perceive as just a series of beeps and blips turns on much more sharply in musicians.aEUR Dr. Devin McAuley, a professor of cognitive science at Michigan State University who wasnaEUR(tm)t involved with the study says, aEURoeThese are exciting findings that fit into a broader body of work. ItaEUR(tm)s also been shown that children with musical training have a slower preferred tempo than kids who havenaEUR(tm)t had training.aEUR The findings might help explain why aEUR"" in my completely unscientific sampling of friends and acquaintances aEUR"" musicians tend to be more tolerant of slow, ambient, droning music (my pal Kevin thrives at a dreamy 0.6 notes per second).","The entrainment effects observed here are presumably the result of one (or many) of these changes. These questions cannot be answered within the scope of this study; however, we present several hypotheses to inspire future research. These hypotheses are not mutually exclusive, and it is likely that the reality lies closer to a combination of factors.","[2.0, 2.0, 1.0, 1.0]",Psychology,test,1.5,news,http://healthmedicinet.com/news/the-neuroscience-of-musical-perception-bass-guitars-and-drake/ 10.1111/desc.12179,Psychology_218,"""What we've shown is that in 3-year-old children, words activate memories that then rapidly deploy attention and lead children to find the relevant object in a cluttered array,"" said Smith, Chancellor's Professor in the Department of Psychological and Brain Sciences.","By hypothesis, the underlying mechanism for these effects may be fundamentally the same as the one proposed here: Heard words yield representations (either expectations or biased encoding of seen things) in visual working memory and these active representations then drive where one looks in a scene.","""If the name of the target object was also said, the children were much faster at finding it and less distracted by the other objects in the scene,"" said Vales, a graduate student in the Department of Psychological and Brain Sciences. ""What we've shown is that in 3-year-old children, words activate memories that then rapidly deploy attention and lead children to find the relevant object in a cluttered array,"" said Smith, Chancellor's Professor in the Department of Psychological and Brain Sciences. ""Words call up an idea that is more robust than an image and to which we more rapidly respond.","For example, adults listening to spoken sentences look at a possible visual referent even when the visual array is irrelevant to the task (for a review see , and even look to shape-similar items when that item is clearly not the referent of the uttered word (e.g. By hypothesis, the underlying mechanism for these effects may be fundamentally the same as the one proposed here: Heard words yield representations (either expectations or biased encoding of seen things) in visual working memory and these active representations then drive where one looks in a scene. The two hypothesized approaches to search illustrated in Figure 6 differ principally in whether the target representation is active throughout search or whether it is activated upon seeing a similar enough item in the array.","[3.0, 4.0, 5.0, 4.0, 1.0]",Psychology,test,4.0,news,http://www.sciencedaily.com/releases/2014/04/140417090838.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29 10.1073/pnas.1407787111,Psychology_234,"""It is particularly noteworthy that the networks we found to have lagging maturation in ADHD are linked to the very behaviors that are the symptoms of ADHD,"" he says.","We found prominent maturational lag in DMN interconnections with VAN, with a concentration of lagged connections involving anterior insula, a key hub in VAN.","These networks, and the connections between them, mature throughout early childhood all the way to young adulthood. ""It is particularly noteworthy that the networks we found to have lagging maturation in ADHD are linked to the very behaviors that are the symptoms of ADHD,"" he says. ""The results of this study set the stage for the next phase of this research, which is to examine individual components of the networks that have the maturational lag,"" he says.","Our results thus add to this network regulation model of ADHD by suggesting a developmental explanation for the observed pattern of network and regional abnormalities. We found prominent maturational lag in DMN interconnections with VAN, with a concentration of lagged connections involving anterior insula, a key hub in VAN. These observations suggest that lagged maturation in anterior insula could contribute to several forms of inattention in ADHD.","[5.0, 2.0, 1.0, 2.0, 1.0]",Psychology,test,2.0,news,http://www.sciencedaily.com/releases/2014/09/140915153607.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29 10.1111/desc.12179,Psychology_249,"For instance, the difference between search times, with and without naming the target object, indicate a key role for a kind of brief visual memory known as working memory, that helps us remember what we just saw as we look to something new.","The present findings offer a potential pathway to understand the in-task mechanisms that lead to biased attention to object shape in naming tasks: Once a child has learned the names of a sufficient number of basic-level categories, naming -even with novel names -may lead to the biased encoding of shape and more active visual working memory representations that then guide attention in novel name learning tasks.","Vales said their research results ""begin to tell us precisely how words help, the kinds of cognitive processes words tap into to change how children behave. For instance, the difference between search times, with and without naming the target object, indicate a key role for a kind of brief visual memory known as working memory, that helps us remember what we just saw as we look to something new. Words put ideas in working memory faster than images.""","By one account, this shape bias emerges as a secondorder generalization across known names and categories and is cued by the common linguistic contexts of naming things . The present findings offer a potential pathway to understand the in-task mechanisms that lead to biased attention to object shape in naming tasks: Once a child has learned the names of a sufficient number of basic-level categories, naming -even with novel names -may lead to the biased encoding of shape and more active visual working memory representations that then guide attention in novel name learning tasks. The present findings and discussion are also relevant to a large literature on the development of working memory in children.","[2.0, 2.0, 3.0, 2.0, 4.0]",Psychology,test,2.6,news,http://www.sciencedaily.com/releases/2014/04/140417090838.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29 10.1111/desc.12179,Psychology_261,"""If the name of the target object was also said, the children were much faster at finding it and less distracted by the other objects in the scene,"" Vales, a graduate student in the Department of Psychological and Brain Sciences, said in a recent statement.","The pattern fits the hypothesis that labeling, by activating categoryspecific shape features of the target in visual working memory, resulted in faster performance with less repetition of the visual information.","Cognitive scientists Catarina Vales and Linda Smith say that their findings open up new avenues for research into the way language shapes the course of developmental disabilities such as ADHD, difficulties with school, and other attention-related problems. ""If the name of the target object was also said, the children were much faster at finding it and less distracted by the other objects in the scene,"" Vales, a graduate student in the Department of Psychological and Brain Sciences, said in a recent statement. ""What we've shown is that in 3-year-old children, words activate memories that then rapidly deploy attention and lead children to find the relevant object in a cluttered array,"" said Smith, Chancellor's Professor in the Department of Psychological and Brain Sciences.","Within the limits of our measures with 3-year-old children (for whom 36 total trials is quite demanding), the results suggest that hearing a label quickly enabled children to more rapidly find the target object amidst distractors and that repeated visual exposures to the target more incrementally led children to just as rapid search. The pattern fits the hypothesis that labeling, by activating categoryspecific shape features of the target in visual working memory, resulted in faster performance with less repetition of the visual information. The four experiments reported here show that hearing the name of an object improves 3-year-old children's ability to find that object in an array.","[3.0, 2.0, 4.0, 5.0, 5.0]",Psychology,test,3.8,news,http://www.redorbit.com/news/health/1113124549/spoken-language-helps-direct-childrens-eyes-041814/ 10.1177/1948550614537308,Psychology_264,The researchers found that students who engaged in casual sex reported higher overall wellbeing.,"Hierarchical linear models (HLM) indicated that after controlling for demographics, higher sociosexuality was linked to a significantly higher likelihood of engaging in weekly casual sex, odds ratio (OR) ¼ 2.31 [1.84, 2.89], p < .001; the interaction with gender was not significant, OR ¼ 0.91 [0.74, 1.13].","Overall, 42 percent of the participants reported having casual sex. The researchers found that students who engaged in casual sex reported higher overall wellbeing. They also reported having less stress and better emotional health.","Average proportion of weeks with casual sex was .09 (SD ¼ .18) per participant; 44% of those with at least one casual sex week reported only one such week (ranging 1-9 weeks). Hierarchical linear models (HLM) indicated that after controlling for demographics, higher sociosexuality was linked to a significantly higher likelihood of engaging in weekly casual sex, odds ratio (OR) ¼ 2.31 [1.84, 2.89], p < .001; the interaction with gender was not significant, OR ¼ 0.91 [0.74, 1.13]. Only 16% of those scoring below the median on sociosexuality engaged in casual sex over the 12 weeks compared to 55% of those scoring above the median.","[4.0, 5.0, 3.0, 2.0, 4.0]",Psychology,test,3.6,news,http://www.counselheal.com/articles/10249/20140626/casual-sex-can-be-good-study-reports.htm 10.1073/pnas.1508431112,Psychology_265,"Moreover, musicians much more accurately detected pitch distortions--as evidenced by corresponding cortical oscillations.","Recordings from nonmusicians demonstrate cortical entrainment that tracks musical stimuli over a typical range of tempi, but not at tempi below 1 note per second.","This difference, the researchers say, may suggest that non-musicians are unable to process the music as a continuous melody rather than as individual notes. Moreover, musicians much more accurately detected pitch distortions--as evidenced by corresponding cortical oscillations. Brain rhythms, they add, therefore appear to play a role in parsing and grouping sound streams into ""chunks"" that are then analyzed as speech or music.","Recordings from nonmusicians demonstrate cortical entrainment that tracks musical stimuli over a typical range of tempi, but not at tempi below 1 note per second. Importantly, the observed entrainment correlates with performance on a concurrent pitch-related behavioral task. In contrast, the data from musicians show that entrainment is enhanced by years of musical training, at all presented tempi.","[2.0, 4.0, 1.0, 3.0]",Psychology,test,2.5,news,http://www.futurity.org/musicians-brains-rhythms-1034492-2/ 10.1177/1948550614537308,Psychology_268,"By the end of the study, 42 percent of subjects reported having sex outside a relationship.","Simple slope analyses indicated that high-SOI participants who had casual sex over the academic year had higher self-esteem (B ¼ 0.14, SE ¼ 0.06, p ¼ .025) and marginally lower depression (B ¼ À0.12, SE ¼ 0.07, p ¼ .091) and anxiety (B ¼ À0.11, SE ¼ 0.06, p ¼ .086) than high-SOI participants who did not have casual sex (Figure 3) .","If you're ""sociosexually restricted,"" it might work the opposite way. By the end of the study, 42 percent of subjects reported having sex outside a relationship. When it came to those who were sociosexually unrestricted, having casual sex was associated with higher self-esteem and life satisfaction and lower depression and anxiety.","The critical interaction term was significant for all three assessed outcomes (all ps < .05). Simple slope analyses indicated that high-SOI participants who had casual sex over the academic year had higher self-esteem (B ¼ 0.14, SE ¼ 0.06, p ¼ .025) and marginally lower depression (B ¼ À0.12, SE ¼ 0.07, p ¼ .091) and anxiety (B ¼ À0.11, SE ¼ 0.06, p ¼ .086) than high-SOI participants who did not have casual sex (Figure 3) . Among low-SOI participants, those who had casual sex did not differ significantly from those who did not have casual sex on self-esteem (B ¼ À0.10, SE ¼ 0.07, p ¼ .168), depression (B ¼ 0.13, SE ¼ 0.08, p ¼ .104), or anxiety (B ¼ 0.11, SE ¼ 0.07, p ¼ .130).","[3.0, 3.0, 3.0, 1.0, 1.0]",Psychology,test,2.2,news,http://www.psmag.com/navigation/health-and-behavior/casual-sex-excellent-people-love-casual-sex-83847/ 10.1073/pnas.1508431112,Psychology_270,"Not surprisingly, the study found that musicians have more potent oscillatory mechanisms than do non-musicians--but this discovery's importance goes beyond the value of musical instruction.",ref.,"""Specifically, our findings show that the presence of these rhythms enhances our perception of music and of pitch changes."" Not surprisingly, the study found that musicians have more potent oscillatory mechanisms than do non-musicians--but this discovery's importance goes beyond the value of musical instruction. ""What this shows is we can be trained, in effect, to make more efficient use of our auditory-detection systems,"" observes study coauthor David Poeppel, a professor in psychology department and Center for Neural Science and director of the Max Planck Institute for Empirical Aesthetics in Frankfurt.","This higher-level network could generate more regular and precise temporal predictions and-through feedback connections-modulate stimulus entrainment to be more accurate (cf. ref. As musical training requires synchronous processing of somatosensory, motor, and visual areas, these areas will likely provide modulatory rhythmic input into auditory cortex, further enhancing entrainment to the musical stimulus.","[1.0, 3.0, 4.0, 1.0, 3.0]",Psychology,test,1.0,news,http://www.futurity.org/musicians-brains-rhythms-1034492-2/ 10.1073/pnas.1508431112,Psychology_279,"For music that is faster than one note per second, both musicians and non-musicians showed cortical oscillations that synchronized with the note rate of the clips--in other words, these oscillations were effectively employed by everyone to process the sounds they heard, although musicians' brains synchronized more to the musical rhythms.","This methodological choice allows us to study the rate of the music without delving into the complexities of beat and meter, which can shift nonmonotonically with increasing overall rate (i.e., faster notes are often arranged into larger groupings).","""Musicians, through their experience, are simply better at this type of processing."" For music that is faster than one note per second, both musicians and non-musicians showed cortical oscillations that synchronized with the note rate of the clips--in other words, these oscillations were effectively employed by everyone to process the sounds they heard, although musicians' brains synchronized more to the musical rhythms. Only musicians, however, showed oscillations that synchronized with unusually slow clips.","Building on effects such as these, we expect that increased entrainment and reliability in musicians' cortical responses may reflect expertise. This methodological choice allows us to study the rate of the music without delving into the complexities of beat and meter, which can shift nonmonotonically with increasing overall rate (i.e., faster notes are often arranged into larger groupings). As the entrainment mechanism occurs for a wide range of acoustic stimuli, we find it unlikely to be following beat or meter in music: such clear groupings do not exist in other stimulus types.","[1.0, 2.0, 2.0, 3.0]",Psychology,test,2.0,news,http://www.futurity.org/musicians-brains-rhythms-1034492-2/ 10.1073/pnas.1508431112,Psychology_282,"And our conscious ability to apply symbolic meaning to sounds, lyrics and song aEUR"" and to recognize when listening to music that what weaEUR(tm)re listening to is supposed to be music aEUR"" also certainly influences human musical perception.",Our data go beyond this for one key reason: the target pitch distortion had no temporally valid prediction.,"How humans perceive music is, of course, far more complicated than simply tuning in to tempo. And our conscious ability to apply symbolic meaning to sounds, lyrics and song aEUR"" and to recognize when listening to music that what weaEUR(tm)re listening to is supposed to be music aEUR"" also certainly influences human musical perception. But the work of Poeppel and others suggests that a tonal time perception hinted at in apes and more fully formed in man could be a prerequisite for discerning a song.",These studies support a dynamic attention theory (or varieties thereof) wherein attentional rhythms align to optimize processing of predicted inputs . Our data go beyond this for one key reason: the target pitch distortion had no temporally valid prediction. It was uniformly distributed throughout the clips and not tied to a particular note in the stimulus.,"[1.0, 1.0, 1.0, 1.0, 1.0]",Psychology,test,1.0,news,http://healthmedicinet.com/news/the-neuroscience-of-musical-perception-bass-guitars-and-drake/ 10.1111/jcpp.12015,Psychology_301,It might make a bigger difference to them at that point that they aren't biologically related to one or both of their parents.,This may also be true of surrogacy children who similarly have to face up to being different at an early age.,"""The friend shrugged her shoulders and they went back to looking through the book,"" she says, adding that she realizes there may be more conversations about the surrogacy as her girls grow older. It might make a bigger difference to them at that point that they aren't biologically related to one or both of their parents. ""We hope to revisit the children next year when they are 14 years-old, as issues to do with identity become important in adolescence ...","Interestingly, the adopted children's behavior problems had reduced by adolescence , as had the behavior problems of the surrogacy children in the present study by age 10. suggested that internationally adopted children struggle with identity issues earlier than domestically adopted children due to their difference in appearance from their parents. This may also be true of surrogacy children who similarly have to face up to being different at an early age. Although the sample sizes were not large and thus small differences between family types may not have been detected, an advantage of the study was that data were collected before the children were aware of their biological origins, allowing the consequences of secrecy versus openness about the nature of their birth to be examined prospectively.","[1.0, 3.0, 3.0, 3.0]",Psychology,test,2.5,news,http://www.today.com/health/new-study-tracks-emotional-health-surrogate-kids-6C10366818 10.1073/pnas.1407787111,Psychology_305,Future studies of brain network maturation in ADHD could shed light into the neural basis for this difference.,Our results provide strong initial evidence that these alterations arise from delays in typical maturational patterns.,"The findings are also relevant to thinking about the longitudinal course of ADHD from childhood to adulthood. Future studies of brain network maturation in ADHD could shed light into the neural basis for this difference. ""But without the database of fMRI images, and the spirit of collaboration that allowed them to be compiled and shared, we would never have reached this point.""","Thus, conventional seedbased strategies are likely to produce summary measures that do not capture underlying fine-grained patterns of variation or can miss trends that are detectable only when looking across large populations of connections. Our results provide strong initial evidence that these alterations arise from delays in typical maturational patterns. Our results invite further investigation into the neurobiological mechanisms in ADHD that produce delays in development of large-scale networks.","[4.0, 3.0, 5.0, 1.0]",Psychology,test,4.0,news,http://www.sciencedaily.com/releases/2014/09/140915153607.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29 10.1073/pnas.1508431112,Psychology_311,Poeppel is quick to acknowledge that his work by no means proves that entrainment equates with being a good musician.,"Building on effects such as these, we expect that increased entrainment and reliability in musicians' cortical responses may reflect expertise.","They might also explain why musicians appear to be more attuned to environmental sounds, like picking out a single voice in the din of a crowded room. Poeppel is quick to acknowledge that his work by no means proves that entrainment equates with being a good musician. aEURoeMaybe youaEUR(tm)re still a really bad piano player despite your brain rhythms locking on, but most of our musicians were conservatory trained so presumably theyaEUR(tm)re pretty good,aEUR he jokes.","Furthermore, prestimulus beta plays a role in generating accurate temporal predictions even in pure listening tasks (9). Building on effects such as these, we expect that increased entrainment and reliability in musicians' cortical responses may reflect expertise. This methodological choice allows us to study the rate of the music without delving into the complexities of beat and meter, which can shift nonmonotonically with increasing overall rate (i.e., faster notes are often arranged into larger groupings).","[3.0, 2.0, 1.0]",Psychology,test,2.0,news,http://healthmedicinet.com/news/the-neuroscience-of-musical-perception-bass-guitars-and-drake/ 10.1073/pnas.1508431112,Psychology_320,"Brain rhythms, they add, therefore appear to play a role in parsing and grouping sound streams into ""chunks"" that are then analyzed as speech or music.","Plausibly, then, music-with its inherent rhythmicity-also drives this system.","This difference, the researchers say, may suggest that non-musicians are unable to process the music as a continuous melody rather than as individual notes. Moreover, musicians much more accurately detected pitch distortions--as evidenced by corresponding cortical oscillations. Brain rhythms, they add, therefore appear to play a role in parsing and grouping sound streams into ""chunks"" that are then analyzed as speech or music.","This suggests that the primary function reflected in this neural pattern is not specific to the task. Plausibly, then, music-with its inherent rhythmicity-also drives this system. What we consider intriguing is that this sensorimotor network, with a primary function in rhythmic processing, affects performance on a nonrhythmic task.","[3.0, 3.0, 2.0, 2.0, 5.0]",Psychology,test,3.0,news,http://www.futurity.org/musicians-brains-rhythms-1034492-2/ 10.1073/pnas.1508431112,Psychology_321,"""What this shows is we can be trained, in effect, to make more efficient use of our auditory-detection systems,"" observes study coauthor David Poeppel, a professor in psychology department and Center for Neural Science and director of the Max Planck Institute for Empirical Aesthetics in Frankfurt.",New data will be required to dissociate between these interpretations.,"Not surprisingly, the study found that musicians have more potent oscillatory mechanisms than do non-musicians--but this discovery's importance goes beyond the value of musical instruction. ""What this shows is we can be trained, in effect, to make more efficient use of our auditory-detection systems,"" observes study coauthor David Poeppel, a professor in psychology department and Center for Neural Science and director of the Max Planck Institute for Empirical Aesthetics in Frankfurt. ""Musicians, through their experience, are simply better at this type of processing.""","This interpretation, although not definitive, demonstrates the temporal structure that an oscillatory mechanism might impose onto the processing of an auditory signal. New data will be required to dissociate between these interpretations. We show that cortical entrainment is enhanced with years of musical training.","[2.0, 1.0, 2.0, 2.0, 2.0]",Psychology,test,1.8,news,http://www.futurity.org/musicians-brains-rhythms-1034492-2/ 10.1073/pnas.1508431112,Psychology_326,"Or, put another way, our brains entrain more to low frequencies.",5B shows the R 2 values demonstrating that phase coherence at the note rate and neighboring frequencies correlate with years of musical training.,"Whatever it means artistically speaking, we can train our brains to respond more precisely to music in a measurable, biologic way. Or, put another way, our brains entrain more to low frequencies. The authors speculate that this could be why the rhythm sections of so many music styles around the world rely on bass, drums and lower tones, and why discordant guitar solos and blaring saxophone leads can sound just fine when off-beat bass guitar doesnaEUR(tm)t. Poeppel cautions that this research is in its early stages, but speculates that if in fact we are more likely to entrain to lower frequencies it could help explain another critical component of musical perception: movement.","Further analysis confirms the robust relationship between musical expertise and entrainment: a linear correlation is tested between ITC, averaged across time in each condition, and the number of years of musical training of each musician. 5B shows the R 2 values demonstrating that phase coherence at the note rate and neighboring frequencies correlate with years of musical training. The corresponding scatter plots (Fig.","[1.0, 2.0, 4.0, 1.0, 1.0]",Psychology,test,1.8,news,http://healthmedicinet.com/news/the-neuroscience-of-musical-perception-bass-guitars-and-drake/ 10.1073/pnas.1508431112,Psychology_329,"""Specifically, our findings show that the presence of these rhythms enhances our perception of music and of pitch changes.""",5B ) indicate a linear relationship.,"The findings also suggest musical training can enhance the functional role of brain rhythms. ""Specifically, our findings show that the presence of these rhythms enhances our perception of music and of pitch changes."" Not surprisingly, the study found that musicians have more potent oscillatory mechanisms than do non-musicians--but this discovery's importance goes beyond the value of musical instruction.","The corresponding scatter plots (Fig. 5B ) indicate a linear relationship. It should be noted that musical training is highly correlated with the age of the participants (R 2 = 0.56, P < 0.005).","[1.0, 1.0, 1.0, 2.0]",Psychology,test,1.25,news,http://www.futurity.org/musicians-brains-rhythms-1034492-2/ 10.1073/pnas.1508431112,Psychology_330,"Or, put another way, our brains entrain more to low frequencies.","We found that neural tracking was stronger above 1 nps than below [experiment 1, t (14) = 2.15, P < 0.05; experiment 2, t (11) = 4.2, P < 0.005].","Whatever it means artistically speaking, we can train our brains to respond more precisely to music in a measurable, biologic way. Or, put another way, our brains entrain more to low frequencies. The authors speculate that this could be why the rhythm sections of so many music styles around the world rely on bass, drums and lower tones, and why discordant guitar solos and blaring saxophone leads can sound just fine when off-beat bass guitar doesnaEUR(tm)t. Poeppel cautions that this research is in its early stages, but speculates that if in fact we are more likely to entrain to lower frequencies it could help explain another critical component of musical perception: movement.","The peak frequency for each stimulus type corresponded to the note rate of the stimulus except for the 0.5 nps condition, which had a peak frequency of 2 nps. We found that neural tracking was stronger above 1 nps than below [experiment 1, t (14) = 2.15, P < 0.05; experiment 2, t (11) = 4.2, P < 0.005]. These findings could suggest a lower limit of the oscillatory mechanism, in which the cortical response is constrained by the inherent temporal structure within the neural architecture.","[2.0, 4.0, 2.0, 1.0, 2.0]",Psychology,test,2.2,news,http://healthmedicinet.com/news/the-neuroscience-of-musical-perception-bass-guitars-and-drake/ 10.1073/pnas.1508431112,Psychology_332,"Moreover, musicians much more accurately detected pitch distortions--as evidenced by corresponding cortical oscillations.",Musical Training Enhances Entrainment.,"This difference, the researchers say, may suggest that non-musicians are unable to process the music as a continuous melody rather than as individual notes. Moreover, musicians much more accurately detected pitch distortions--as evidenced by corresponding cortical oscillations. Brain rhythms, they add, therefore appear to play a role in parsing and grouping sound streams into ""chunks"" that are then analyzed as speech or music.","This relationship demonstrates that faithful tracking enhances processing of the auditory stimulus, even when the task is not temporal but pitch-based. Musical Training Enhances Entrainment. As expected, we found ( Importantly, we also found a main effect of musical expertise [F (1,66) = 9.12, P < 0.005].","[3.0, 2.0, 3.0, 2.0, 1.0]",Psychology,test,2.2,news,http://www.futurity.org/musicians-brains-rhythms-1034492-2/ 10.1073/pnas.1508431112,Psychology_333,"aEURoeOur brains can lay down beats anywhere on a continuously moving visual stimulus,aEUR says McAuley.",ref.,"aEURoeRhythmic input also automatically activates your motor cortex too. aEURoeOur brains can lay down beats anywhere on a continuously moving visual stimulus,aEUR says McAuley. It seems that though we entrain accurately to an auditory beat, we appear to allow some rhythmic leeway with visual input.","This higher-level network could generate more regular and precise temporal predictions and-through feedback connections-modulate stimulus entrainment to be more accurate (cf. ref. As musical training requires synchronous processing of somatosensory, motor, and visual areas, these areas will likely provide modulatory rhythmic input into auditory cortex, further enhancing entrainment to the musical stimulus.","[1.0, 1.0, 1.0, 1.0, 1.0]",Psychology,test,1.0,news,http://healthmedicinet.com/news/the-neuroscience-of-musical-perception-bass-guitars-and-drake/ 10.1073/pnas.1508431112,Psychology_344,"Or, put another way, our brains entrain more to low frequencies.","Still, as both types of complex sounds require the same function, broadly construed-the identification of meaningful units within a continuous sound stream-it is plausible that they perform this function using the same or a similar mechanism.","Whatever it means artistically speaking, we can train our brains to respond more precisely to music in a measurable, biologic way. Or, put another way, our brains entrain more to low frequencies. The authors speculate that this could be why the rhythm sections of so many music styles around the world rely on bass, drums and lower tones, and why discordant guitar solos and blaring saxophone leads can sound just fine when off-beat bass guitar doesnaEUR(tm)t. Poeppel cautions that this research is in its early stages, but speculates that if in fact we are more likely to entrain to lower frequencies it could help explain another critical component of musical perception: movement.","Given our conjecture that this entrainment mechanism is shared between speech and music, we suppose that it would. Still, as both types of complex sounds require the same function, broadly construed-the identification of meaningful units within a continuous sound stream-it is plausible that they perform this function using the same or a similar mechanism. If musical training enhances cortical entrainment to speech for example, as has been reported for auditory brainstem responses , then it may provide an explanation for findings related to music and dyslexia.","[1.0, 1.0, 5.0, 3.0, 3.0]",Psychology,test,3.0,news,http://healthmedicinet.com/news/the-neuroscience-of-musical-perception-bass-guitars-and-drake/ 10.1073/pnas.1508431112,Psychology_345,However the musiciansaEUR(tm) brain waves buzzed in synchrony to music as slow as 0.7 notes per second.,"These findings could suggest a lower limit of the oscillatory mechanism, in which the cortical response is constrained by the inherent temporal structure within the neural architecture.","They found that the brain wave rhythms of nonmusicians didnaEUR(tm)t entrain to music with a tempo less than one note per second, or what would be considered slow music. However the musiciansaEUR(tm) brain waves buzzed in synchrony to music as slow as 0.7 notes per second. aEURoeIt looks like musicians can take longer, more drawn out musical phrases and group them into a pattern of some kind,aEUR says Poeppel, aEURoethe response to what some people perceive as just a series of beeps and blips turns on much more sharply in musicians.aEUR Dr. Devin McAuley, a professor of cognitive science at Michigan State University who wasnaEUR(tm)t involved with the study says, aEURoeThese are exciting findings that fit into a broader body of work.","We found that neural tracking was stronger above 1 nps than below [experiment 1, t (14) = 2.15, P < 0.05; experiment 2, t (11) = 4.2, P < 0.005]. These findings could suggest a lower limit of the oscillatory mechanism, in which the cortical response is constrained by the inherent temporal structure within the neural architecture. 3C shows the entrainment of the musicians to the same stimuli used in experiment 2.","[1.0, 2.0, 3.0, 1.0, 3.0]",Psychology,test,2.0,news,http://healthmedicinet.com/news/the-neuroscience-of-musical-perception-bass-guitars-and-drake/ 10.1177/1948550614537308,Psychology_349,The authors argue that there would be no reason to believe that this effect wouldn't extend to casual sex.,Average proportion of weeks with casual sex was .09 (SD ¼ .18) per participant; 44% of those with at least one casual sex week reported only one such week (ranging 1-9 weeks).,"""Sociosexual orientation is a relatively stable tendency toward or away from casual sex, determined by a combination of heritable factors, sociocultural learning, and past experiences, and reflected in three key components: motivation for, attitudes toward, and past experience with casual sex,"" the authors write. The authors argue that there would be no reason to believe that this effect wouldn't extend to casual sex. If you are ""sociosexually unrestricted,"" or you desire casual sex, you might derive psychological benefits from feeling like you're acting authentically while having it.","At least 1 week with casual sex was reported by 80 (35%) participants; these percentages were similar in both sexes, w 2 (1) < 1. Average proportion of weeks with casual sex was .09 (SD ¼ .18) per participant; 44% of those with at least one casual sex week reported only one such week (ranging 1-9 weeks). Hierarchical linear models (HLM) indicated that after controlling for demographics, higher sociosexuality was linked to a significantly higher likelihood of engaging in weekly casual sex, odds ratio (OR) ¼ 2.31 [1.84, 2.89], p < .001; the interaction with gender was not significant, OR ¼ 0.91 [0.74, 1.13].","[4.0, 4.0, 3.0, 3.0, 3.0]",Psychology,test,3.4,news,http://www.psmag.com/navigation/health-and-behavior/casual-sex-excellent-people-love-casual-sex-83847/ 10.1073/pnas.1508431112,Psychology_352,"Only musicians, however, showed oscillations that synchronized with unusually slow clips.",10 and 42).,"For music that is faster than one note per second, both musicians and non-musicians showed cortical oscillations that synchronized with the note rate of the clips--in other words, these oscillations were effectively employed by everyone to process the sounds they heard, although musicians' brains synchronized more to the musical rhythms. Only musicians, however, showed oscillations that synchronized with unusually slow clips. This difference, the researchers say, may suggest that non-musicians are unable to process the music as a continuous melody rather than as individual notes.","The fact that the beta effect is more centrally located than the auditory channels supports the hypothesis that the source of the beta oscillation is a part of a sensorimotor synchronization network (e.g., refs. 10 and 42). (It should be noted that we are unable to confirm this without source localization, which we are unable to perform due to a lack of anatomical MRI scans for the participants of this study.)","[2.0, 3.0, 1.0, 1.0, 1.0]",Psychology,test,1.6,news,http://www.futurity.org/musicians-brains-rhythms-1034492-2/ 10.1073/pnas.1508431112,Psychology_365,Poeppel is quick to acknowledge that his work by no means proves that entrainment equates with being a good musician.,"As the entrainment mechanism occurs for a wide range of acoustic stimuli, we find it unlikely to be following beat or meter in music: such clear groupings do not exist in other stimulus types.","They might also explain why musicians appear to be more attuned to environmental sounds, like picking out a single voice in the din of a crowded room. Poeppel is quick to acknowledge that his work by no means proves that entrainment equates with being a good musician. aEURoeMaybe youaEUR(tm)re still a really bad piano player despite your brain rhythms locking on, but most of our musicians were conservatory trained so presumably theyaEUR(tm)re pretty good,aEUR he jokes.","This methodological choice allows us to study the rate of the music without delving into the complexities of beat and meter, which can shift nonmonotonically with increasing overall rate (i.e., faster notes are often arranged into larger groupings). As the entrainment mechanism occurs for a wide range of acoustic stimuli, we find it unlikely to be following beat or meter in music: such clear groupings do not exist in other stimulus types. We demonstrate that cortical oscillatory activity in both low (<8 Hz) and high (15-30 Hz) frequencies is tightly coupled to behavioral performance in musical listening, in a bidirectional manner.","[2.0, 3.0, 2.0, 2.0]",Psychology,test,2.25,news,http://healthmedicinet.com/news/the-neuroscience-of-musical-perception-bass-guitars-and-drake/ 10.1073/pnas.1407787111,Psychology_385,"So, the new findings build on that understanding and add to it.",Visualization of the pattern of altered connections revealed prominent lag in segregation between anterior insula in VAN and PCC in DMN.,"The new findings mesh well with what other researchers have found by examining the physical structure of the brains of people with and without ADHD in other ways. So, the new findings build on that understanding and add to it. The findings are also relevant to thinking about the longitudinal course of ADHD from childhood to adulthood.","The odds that a strongly maturing connection was lagged (vs. being unlagged) were 2.21 to 1, which is statistically significant (P < 0.03; permutation test). Visualization of the pattern of altered connections revealed prominent lag in segregation between anterior insula in VAN and PCC in DMN. or Conners' Rating Scale, 3rd Edition (39) was available for 180 (ADHD = 77) of the 421 participants in the present analysis (other participants had either different measures of ADHD symptom severity or none at all).","[2.0, 1.0, 3.0, 1.0]",Psychology,test,1.75,news,http://www.newswise.com/articles/slow-to-mature-quick-to-distract-adhd-brain-study-finds-slower-development-of-key-connections 10.1093/geronb/gbw112,Psychology_404,"Interestingly, lower negative quality ties reported by wives exacerbated the effect of wife stress on husbands' waist circumference, says Kira Birditt, a research associate professor at ISR's Survey Research Center.","Likewise, husbands' greater chronic stress exposure was associated with increased waist circumference among wives when husbands reported higher negative marital quality.","Related Coverage How You Argue May Predict Future Health Trouble Greater negative quality ties as reported by husbands exacerbated the effects of partner stress on both husbands' and wives' waist circumference. Interestingly, lower negative quality ties reported by wives exacerbated the effect of wife stress on husbands' waist circumference, says Kira Birditt, a research associate professor at ISR's Survey Research Center. For the increased risk of obesity, 59 percent of the husbands and 64 percent of the wives were at higher risk of disease in the study's first assessment, and 66 percent of husbands and 70 percent of wives were at increased risk at the study's conclusion.","Wives' greater chronic stress exposure was associated with increased waist circumference among husbands when husbands reported higher negative marital quality. Likewise, husbands' greater chronic stress exposure was associated with increased waist circumference among wives when husbands reported higher negative marital quality. In contrast, wives' greater chronic stress exposure was associated with increased waist circumference among husbands when wives' reported lower negative marital quality.","[3.0, 2.0, 4.0, 4.0, 3.0]",Psychology,test,3.2,news,http://www.theepochtimes.com/n3/2172390-your-stress-can-add-inches-to-your-spouses-waist/ 10.1177/0956797619838762,Psychology_407,"Two more experiments indicated that the angle of the eyebrows drove this effect -- downward-tilted heads had eyebrows that appeared to take more of a V shape, even though the eyebrows had not moved from a neutral position, and this was associated with perceptions of dominance.","Finally, the indirect effect of head tilt on perceptions of dominance via eyebrow V-shape was significant, b =.16, p < .01, 95% CI [.11 to .22].","That is, participants rated downward-tilted heads as more dominant even when they could only see the eyes and eyebrows; this was not true when the rest of the face was visible and the eyes and eyebrows were obscured. Two more experiments indicated that the angle of the eyebrows drove this effect -- downward-tilted heads had eyebrows that appeared to take more of a V shape, even though the eyebrows had not moved from a neutral position, and this was associated with perceptions of dominance. ""In other words, tilting the head downward can have the same effect on social perceptions as does lowering one's eyebrows -- a movement made by the corrugator muscle, known as Action Unit 4 in the Facial Action Coding System -- but without any actual facial movement,"" say Witkower and Tracy.","The direct effect of head tilt on perceptions of dominance while controlling for eyebrow V-shape was significant but partially attenuated, b = .17, t = 3.26, p < .001, 95% CI: [.07 to .27]. Finally, the indirect effect of head tilt on perceptions of dominance via eyebrow V-shape was significant, b =.16, p < .01, 95% CI [.11 to .22]. Follow-up models outlining the a and b pathways while estimating additional random slopes and covariates, or using different analyses (e.g., repeated measures ANOVA), did not change the statistical significance or the direction of other pathways in the model (see Table 1 and SOM-U).","[5.0, 5.0, 3.0, 2.0, 4.0]",Psychology,test,3.8,news,http://ct.moreover.com/?a=39454880621&p=1pl&v=1&x=hzaP3DIbQk-evDBTq1czHA 10.1073/pnas.1415800112,Psychology_415,"Some of these personality traits were matched with particular urban characteristics: high openness to experience was found in neighborhoods with low income and employment rates, while neighborhoods with high income also had higher life satisfaction.","Openness to experience was associated with lower neighborhood income and employment rate, lower voting activity, higher crime rates, and higher proportion of people receiving income and disability support, whereas the reverse correlations with these neighborhood characteristics were observed for life satisfaction.","Central London was characterized by high openness to experience but low conscientiousness, while high levels of extraversion and emotional stability were associated with the southwest boroughs. Some of these personality traits were matched with particular urban characteristics: high openness to experience was found in neighborhoods with low income and employment rates, while neighborhoods with high income also had higher life satisfaction. Emotional stability and extraversion have previously been linked to life satisfaction, and the authors found this held true regardless of what kind of neighborhood one was in.","Emotional stability (r=0.30) and agreeableness (r=0.32) had slightly higher spatial autocorrelations than conscientiousness. Openness to experience was associated with lower neighborhood income and employment rate, lower voting activity, higher crime rates, and higher proportion of people receiving income and disability support, whereas the reverse correlations with these neighborhood characteristics were observed for life satisfaction. Higher levels of agreeableness were observed in neighborhoods with lower population density and lower housing prices, greater proportion of older people and families with children, and more land area used for domestic gardens and green spaces.","[5.0, 5.0, 4.0]",Psychology,test,4.666666666666667,news,http://arstechnica.com/science/2015/01/your-personality-influences-where-you-live-and-how-happy-youll-be-there/ 10.1152/jn.00140.2013,Psychology_419,"With the added touch sensation, also called haptic feedback, the participants made about half as many errors in the task, the researchers reported.","By assuming that 3 ϽϽ 2 Ͻ 1, the distribution will tend to quickly converge to the metastable distribution, making Eq.","It's very much like watching them move their feet as they run. With the added touch sensation, also called haptic feedback, the participants made about half as many errors in the task, the researchers reported. ""We have a pretty good understanding as to why,"" said Cowan, who has been an amateur juggler since middle school.","In fact, if the initial condition is a random variable that is drawn from the metastable distribution, Eq. By assuming that 3 ϽϽ 2 Ͻ 1, the distribution will tend to quickly converge to the metastable distribution, making Eq. The vector of MFPTs ( mfpt ) for all nonabsorbing states can be computed as Fig.","[1.0, 2.0, 1.0, 1.0]",Psychology,test,1.25,news,http://www.newswise.com/articles/no-clowning-around-juggling-sheds-light-on-how-we-run 10.1186/2044-7248-2-21,Psychology_423,"a plastic spoon is light), yoghurt seemed denser and more expensive.","There was also a significant effect of Spoon Weight on the perceived expensiveness of the yoghurt (F 1,34 = 4.413, P = .043, eta 2 p = .115, see Figure 1b ).","They found that when the weight of the cutlery confirms expectations (e.g. a plastic spoon is light), yoghurt seemed denser and more expensive. Color contrast is also an important factor: white yoghurt when eaten from a white spoon was rated sweeter, more liked, and more expensive than pink-colored yoghurt.","There was a significant effect of Spoon Weight on the perceived density of the yoghurt (F 1,34 = 4.280, P = .046, eta 2 p = .112, see Figure 1a ). There was also a significant effect of Spoon Weight on the perceived expensiveness of the yoghurt (F 1,34 = 4.413, P = .043, eta 2 p = .115, see Figure 1b ). The sampled yoghurt was rated as tasting denser and more expensive when sampled from the lighter spoons, as compared to the visually identical but heavier spoon.","[5.0, 5.0, 5.0, 5.0]",Psychology,test,5.0,news,http://www.sciencedaily.com/releases/2013/06/130626113420.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29 10.1001/jamapsychiatry.2014.1126,Psychology_431,"When researchers from Stanford University of Medicine were examining sleeping patterns in adults over a 10 year-period, 20 participants out of the group of 420 unfortunately committed suicide.","This demonstrates the importance of assessing disturbed sleep in the presence of other, well-established and robust risk factors for suicide.","This is not the first study, however, to link self-harming behaviors with lack of sleep. When researchers from Stanford University of Medicine were examining sleeping patterns in adults over a 10 year-period, 20 participants out of the group of 420 unfortunately committed suicide. Most surprisingly, though, was that this seemed to be the case despite a lack of history with depression for most of these participants.","Our results nevertheless indicated that the endorsement of higher depressive symptoms and sleep disturbances yielded greatest risk for death by suicide. This demonstrates the importance of assessing disturbed sleep in the presence of other, well-established and robust risk factors for suicide. The present study contributes to the extant literature in several ways.","[2.0, 4.0, 5.0, 4.0]",Psychology,test,3.75,news,http://www.medicaldaily.com/teenagers-poor-sleep-habits-insomnia-more-likely-self-harm-345242 10.1016/j.psyneuen.2018.11.032,Psychology_444,"Even before treatment started, levels of interleukin-10 were higher among the 18 patients who later developed long-term fatigue, suggesting the immune system may have been primed to overreact, the study authors explained.","Our study confirms and extends findings from previous longitudinal studies of post-infective fatigue syndrome, which have observed greater fatigue at initial presentation to clinics, around four weeks post-infection, in those who would go on to experience persistent fatigue VollmerConna et al., 2007) .","Those 18 patients had a much stronger immune response during treatment with interferon-alpha, with a doubling in the levels of immune system messenger molecules called interleukin-10 and interleukin-6, according to the report. Even before treatment started, levels of interleukin-10 were higher among the 18 patients who later developed long-term fatigue, suggesting the immune system may have been primed to overreact, the study authors explained. Yet, there was no difference before treatments between the groups in their levels of fatigue or in psychiatric symptoms, like depression or recent stressful events, the scientists noted.","Of note, PF is not due to worse recovery from the effects of IFN-α treatment per se, since the changes in clinical symptoms over the sixmonths post-treatment reveal a similar rate of recovery in both the PF and the RF groups. Our study confirms and extends findings from previous longitudinal studies of post-infective fatigue syndrome, which have observed greater fatigue at initial presentation to clinics, around four weeks post-infection, in those who would go on to experience persistent fatigue VollmerConna et al., 2007) . Interestingly, by adding a 'baseline' assessment before IFN-α (i.e., equivalent to a hitherto unavailable fatigue measurement before the infection), our study shows that pre-treatment levels of fatigue are not a good predictor of the development of CFS in response to an immune challenge.","[2.0, 3.0, 4.0, 4.0, 5.0]",Psychology,test,3.6,news,http://ct.moreover.com/?a=38008201392&p=1pl&v=1&x=WNe_4Xr_bjk4-tomG5DVzA 10.1007/s10071-018-1213-z,Psychology_449,"""We thought that we might find a few of these gestures -- reaching out your palm to ask for something or sticking your hand up in the air -- but we were amazed to see so many of the 'ape' gestures used by the children,"" Dr. Hobaiter said.","The single use cases would not normally be included in a gestural repertoire, see above, but are included here for completeness given the small data set.","The study authors were surprised by just how many gestures the children had in common with our ape cousins. ""We thought that we might find a few of these gestures -- reaching out your palm to ask for something or sticking your hand up in the air -- but we were amazed to see so many of the 'ape' gestures used by the children,"" Dr. Hobaiter said. The researchers found that like young apes, the young children used these gestures in a similar way: combining them together to ask for different things.","However, 7 of these were only coded as used in intentional communication on a single occasion, and the other 4 on n = 2 occasions. The single use cases would not normally be included in a gestural repertoire, see above, but are included here for completeness given the small data set. Given both the correlation between frequency of gesturing and number of gesture types used described above, and the correlation between the number of times a gesture occurred in a child's repertoire and its frequency in the data set (Pearson's correlation, r = 0.80, n = 51, P < 0.0001), the individual repertoires and the frequency with which a gesture was used by different children appear to be determinedly largely by sample size in our data.","[1.0, 3.0, 3.0, 5.0, 2.0]",Psychology,test,2.0,news,http://feedproxy.google.com/~r/BreakingScienceNews/~3/-WA96ZniGzA/infants-gestures-06405.html 10.1177/0956797618813092,Psychology_454,"Together, these findings suggest that competence and masculinity are correlated components of first impressions based on appearance.","Thus, the results show that confidence and masculinity cues are important ingredients of competence impressions-ingredients that cannot be explained as a by-product of attractiveness.","In another online experiment, the researchers discovered a clear gender bias: When participants were asked to identify faces as either male or female, they tended to rate more competent faces as male and less competent faces as female. Together, these findings suggest that competence and masculinity are correlated components of first impressions based on appearance. Again, they found a gender bias in first impressions: As male faces increased in masculinity, so did their perceived competence.","It follows that the variance in the competence impressions cannot be attributed to the halo effect of attractiveness, which is a significant natural confound of competence impressions. Thus, the results show that confidence and masculinity cues are important ingredients of competence impressions-ingredients that cannot be explained as a by-product of attractiveness. Masculinity cues are strongly related to perceptions of gender, which suggests the presence of gender biases in competence impressions.","[4.0, 3.0, 4.0, 4.0]",Psychology,test,3.75,news,http://ct.moreover.com/?a=37922950547&p=1pl&v=1&x=VKCu2NU_eWH3Z2ZWJzO7Ew 10.1111/jopy.12047,Psychology_456,"""Athletes with autonomous motives put in more effort and persisted for longer which helped them reach higher levels of performance with increasingly difficult but attainable goals.","Practitioners who aim to facilitate effective goal setting in sport, business, and educational settings would benefit from guidelines for developing autonomous motivation.","""We found autonomous motives such as enjoyment or personal importance were a double-edged sword,"" explained Professor Sedikides, a social and personality psychologist from the University of Southampton. ""Athletes with autonomous motives put in more effort and persisted for longer which helped them reach higher levels of performance with increasingly difficult but attainable goals. Yet when the goal became unachievable, they had great difficulty realising this, which led to brooding over the failure as the athletes struggled to disengage from the goal.""","Such motivation can be beneficial, behaviorally and affectively, especially when goals become increasingly difficult over time. Practitioners who aim to facilitate effective goal setting in sport, business, and educational settings would benefit from guidelines for developing autonomous motivation. To conclude, the present research supports and extends previous findings regarding the role of autonomous motivation for adaptive goal striving.","[4.0, 4.0, 4.0, 4.0, 4.0]",Psychology,test,4.0,news,http://www.sciencedaily.com/releases/2013/06/130624075854.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29 10.1002/erv.2576,Psychology_462,"They suggest that hormones primarily improves body dissatisfaction, which in turn reduces levels of perfectionism and symptoms of anxiety, and increases self-esteem.","Low self-esteem made the largest contribution to the variance, followed by high levels of perfectionism, body dissatisfaction, and symptoms of anxiety (see Table 4 ).","Professor Arcelus added: ""These findings help to clarify the mechanisms through which hormone treatment might be able to improve eating disorder symptoms in this population. They suggest that hormones primarily improves body dissatisfaction, which in turn reduces levels of perfectionism and symptoms of anxiety, and increases self-esteem. In combination, these factors then appear to alleviate eating disorder symptoms.","Overall, this model was significant and explained 25% of the total variance in bulimia (see Table 4 ). Low self-esteem made the largest contribution to the variance, followed by high levels of perfectionism, body dissatisfaction, and symptoms of anxiety (see Table 4 ). The average VIF for this model was 1.38 and the average tolerance was 0.75 indicating that there is no multicollinearity within the model .","[4.0, 4.0, 4.0, 3.0]",Psychology,test,3.75,news,http://healthmedicinet.com/news/hormone-therapy-may-reduce-eating-disorder-symptoms-in-transgender-people/ 10.1073/pnas.1302159110,Psychology_470,Babies may recognize words that they hear in the womb.,"In infancy, auditory learning implicates the formation and strengthening of neural long-term memory traces, improving discrimination skills, in particular those forming the prerequisites for speech perception and understanding.",Babies may recognize words that they hear in the womb. The team said their research showed that babies in the womb hear the words being said around them -- and they remember them too. The claim may seem incredible.,"In infancy, auditory learning implicates the formation and strengthening of neural long-term memory traces, improving discrimination skills, in particular those forming the prerequisites for speech perception and understanding. Here we demonstrate direct neural correlates of human fetal learning of speech-like auditory stimuli. We presented variants of words to fetuses; unlike infants with no exposure to these stimuli, the exposed fetuses showed enhanced brain activity (mismatch responses) in response to pitch changes for the trained variants after birth.","[3.0, 4.0, 3.0, 3.0]",Psychology,test,3.25,news,http://www.inquisitr.com/924164/babies-words-womb-study/ 10.1016/j.biopsych.2018.12.023,Psychology_496,"If these results are replicated, they imply that prioritizing policies and interventions to children who experienced adversity during those years may help reduce the long-term risk for problems like depression.""",These results suggest that the SLCMA allowed us to more effectively identify methylation differences among children with and without a history of exposure to adversity.,"""These findings suggest that the first three years of life may be an especially important period for shaping biological processes that ultimately give rise to mental health conditions. If these results are replicated, they imply that prioritizing policies and interventions to children who experienced adversity during those years may help reduce the long-term risk for problems like depression."" This is seen in both humans and animals.","Similarly, the top CpG site in the SLCMA (cg19157140), which suggested a sensitive period at age 1.75 associated with the effects of neighborhood disadvantage, was nonsignificant in the corresponding EWAS ( =0.001; p=0.0002; Figure 5 ). These results suggest that the SLCMA allowed us to more effectively identify methylation differences among children with and without a history of exposure to adversity. There was no evidence in support of compound theoretical models, whereby more than one theoretical model explained the most outcome variability.","[4.0, 2.0, 2.0, 2.0, 1.0]",Psychology,test,2.2,news,http://ct.moreover.com/?a=39129268456&p=1pl&v=1&x=idfrljRD125qrYLtqCeZVw 10.1093/cercor/bhr315,Psychology_520,It's just the way our brains work.,"One possibility is that new stimuli showed some variability in terms of conceptual processing fluency, and this fluency was sometimes attributed to repetition (oldness), leading to a selective response bias for a subset of conceptually meaningful stimuli.","In the contours and colors of the lunar surface, people can find meaningful figures for the same reason that we ""see"" the face of Elvis in a potato chip or Jesus in a grilled cheese sandwich. It's just the way our brains work. ""About half end up being meaningful, on average,"" Voss said.","Importantly, the brain activations related to the bias were highly similar to those related to conceptual fluency due to stimulus repetition (i.e., reduced activity in left inferior and superior frontal gyrus). One possibility is that new stimuli showed some variability in terms of conceptual processing fluency, and this fluency was sometimes attributed to repetition (oldness), leading to a selective response bias for a subset of conceptually meaningful stimuli. This interpretation will require additional direct evidence, but our results nonetheless suggest that the pareidolia experience might also provide a useful model for investigating mechanisms of fluency-based biases in recognition memory judgments.","[4.0, 4.0, 1.0, 2.0, 3.0]",Psychology,test,2.8,news,http://news.nationalgeographic.com/news/2014/04/140412-moon-faces-brain-culture-space-neurology/ 10.1007/s11205-018-2028-7,Psychology_532,"The researchers suggest this increase may be because part-time working mothers feel the need to work longer to compensate for the possible stigma, perceived or otherwise, attached to them by other workers, especially when their schedules do not match normal working hours.",We argue that these arrangements measure flexible working primarily aimed to enhance performance outcomes.,"Notably, though, the research also found that although full-time working mothers did not appear to increase their unpaid overtime, part-time working mothers did work more unpaid overtime, with an average of around 20 minutes more a week, which was surprising. The researchers suggest this increase may be because part-time working mothers feel the need to work longer to compensate for the possible stigma, perceived or otherwise, attached to them by other workers, especially when their schedules do not match normal working hours. It may also be that part-time working mothers have a greater ability to work unpaid overtime compared to full-time working mothers.","Understanding Society data captures workers access to and use of the arrangements specified in this legislation, including flexitime and teleworking, which we understand as arrangements aimed primarily to enhance the work-life balance of workers. We argue that these arrangements measure flexible working primarily aimed to enhance performance outcomes. Again, despite the possibility of these arrangements indirectly enabling the achievement of the other goals, we expect that the primary goals of these arrangements may shape the way they influence the outcomes.","[2.0, 3.0, 3.0, 1.0, 3.0]",Psychology,test,2.4,news,https://www.sciencedaily.com/releases/2019/01/190115132822.htm 10.1002/ejsp.2331,Psychology_537,"""This is sort of the same thing responsible for a lot of superstitions over the span of human history.","A MANOVA on the dependent variables revealed a significant multivariate effect of the manipulation, F(3, 201) = 2.64, p = .050; η 2 = .04.","If we couldn't see any patterns, we'd be doomed to make the same mistakes over and over. ""This is sort of the same thing responsible for a lot of superstitions over the span of human history. That's why we get those beliefs of good or bad luck - because we constructed a pattern based on the evidence available at the time.""","If this were true, one would expect that evaluating the structured Vasarely paintings, in which most people detect patterns, would increase these beliefs as compared to evaluating the unstructured Pollock paintings, which most people consider to be relatively chaotic and devoid of patterns. A MANOVA on the dependent variables revealed a significant multivariate effect of the manipulation, F(3, 201) = 2.64, p = .050; η 2 = .04. The univariate effect was significant for belief in existing conspiracy theories, F(1, 203) = 6.84, p = .010, η 2 = .03, and for supernatural beliefs, F(1, 203) = 3.89, p = .050; η 2 = .02, but not for belief in fictitious conspiracy theories, F(1, 203) = 1.15, p = .284.","[1.0, 2.0, 1.0, 1.0, 1.0]",Psychology,test,1.2,news,https://science.howstuffworks.com/life/inside-the-mind/human-brain/conspiracy-theorists-brains-really-are-different.htm#mkcpgn=rssnws1 10.1177/1533317514545377,Psychology_538,"A New Connection The training also helps the patient and caregiver accept new ways of communicating, scientists say.","In this analysis, the improvement amounted to 1.6 points for the patient group and 1.9 points for the caregiver group.","This is the first study to show that the caregiver and the patient both benefit from undergoing mindfulness training together. A New Connection The training also helps the patient and caregiver accept new ways of communicating, scientists say. ""The practice of mindfulness places both participants in the present and focuses on positive features of the interaction, allowing for a type of connection that may substitute for the more complex ways of communicating in the past.","In a further analysis with data from this outlier excluded, the average depression score decreased by 1.7 points (F 1,34 ¼ 11.28, P ¼ .002). In this analysis, the improvement amounted to 1.6 points for the patient group and 1.9 points for the caregiver group. Although the absolute magnitude of these effects is small, these values should be interpreted in light of the fact that 70% of the participants started out in the normal range, such that in most participants there was very little room for improvement.","[2.0, 3.0, 4.0, 2.0, 4.0]",Psychology,test,3.0,news,http://www.theepochtimes.com/n3/914345-how-mindfulness-can-ease-burden-of-dementia/ 10.1073/pnas.1407787111,Psychology_54,That lag in connection development may help explain why people with ADHD get easily distracted or struggle to stay focused.,These advances raise possibilities for investigating maturational lag in ADHD in the developing ICN architecture of the brain .,"That lag in connection development may help explain why people with ADHD get easily distracted or struggle to stay focused. What's more, the new findings, and the methods used to make them, may one day allow doctors to use brain scans to diagnose ADHD -- and track how well someone responds to treatment. The researchers found lags in development of connection within the internally-focused network, called the default mode network or DMN, and in development of connections between DMN and two networks that process externally-focused tasks, often called task-positive networks, or TPNs.","Our finding of maturational lag specifically in connections within and between these networks suggests a developmental etiology for the deficits proposed in these models. These advances raise possibilities for investigating maturational lag in ADHD in the developing ICN architecture of the brain . Thus, conventional seedbased strategies are likely to produce summary measures that do not capture underlying fine-grained patterns of variation or can miss trends that are detectable only when looking across large populations of connections.","[3.0, 4.0, 4.0, 1.0, 3.0]",Psychology,test,3.0,news,http://www.sciencedaily.com/releases/2014/09/140915153607.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29 10.1016/j.neuron.2015.03.023,Psychology_544,"In sum, the study found entirely different neural substrates at initial clinical detection that precede and underlie later good versus poor language outcome in autism.","Comparing these different classifiers based on area under the curve (AUC) values, we find that the multimodal combination of clinical intake measures plus left hemisphere superior temporal cortex activation outperformed all other classifiers (AUC = 81).","In contrast, ASD toddlers with poor language outcomes had superior temporal cortices that showed diminished or abnormal inactivity to speech. In sum, the study found entirely different neural substrates at initial clinical detection that precede and underlie later good versus poor language outcome in autism. These findings, said researchers, will open new avenues of progress towards identifying the causes and best treatment for these two very different types of autism.","In ASD Good, however, this atypical reversal was less severe when assessing the brain-outcome behavioral relationship, and this may be indicative of a different developmental process emerging in ASD Good that allows such brain-behavioral relationships to approach those seen in LD/DD. Comparing these different classifiers based on area under the curve (AUC) values, we find that the multimodal combination of clinical intake measures plus left hemisphere superior temporal cortex activation outperformed all other classifiers (AUC = 81). Classifiers that used either ADOS alone, clinical intake measures alone, or fMRI alone performed similarly in terms of near-identical AUC values (AUC ranging from 67 to 70) (see Figure 5 ).","[2.0, 1.0, 4.0]",Psychology,test,1.0,news,http://healthmedicinet.com/news/brain-imaging-explains-reason-for-good-and-poor-language-outcomes-in-asd-toddlers/ 10.1177/0956797613489890,Psychology_552,"""Our findings suggest that these social means of learning promote superior down-regulation of learned fear, as compared to the sole experiences of personal safety.""","It can be speculated that this process involves the top-down impact on the amygdala by the dorsal mPFC in concert with other prefrontal regions, including the vmPFC, and memoryrelated regions in the hippocampal complex.","The research, published in Psychological Science, a journal of the Association for Psychological Science, indicates that this type of vicarious social learning may be more effective than direct personal experience in extinguishing fear responses. ""Our findings suggest that these social means of learning promote superior down-regulation of learned fear, as compared to the sole experiences of personal safety."" Participants who watched a movie clip that included an actual person -- the social learning condition -- showed significantly less fear response to the target face than those who watched a similar clip that didn't include a person.","In our paradigm, watching the calm learning model during extinction might have imbued the CS+ with a safety value resulting in the abolished return of fear during the reinstatement-test stage. It can be speculated that this process involves the top-down impact on the amygdala by the dorsal mPFC in concert with other prefrontal regions, including the vmPFC, and memoryrelated regions in the hippocampal complex. The potency of vicarious extinction in our study is conceptually similar to earlier work in monkeys showing that observing a fearless learning model can cause latent inhibition or ""immunization"" against subsequent fear learning .","[2.0, 2.0, 3.0, 2.0, 4.0]",Psychology,test,2.6,news,http://www.sciencedaily.com/releases/2013/09/130916091220.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29 10.1002/icd.580,Psychology_570,Maybe nobody misses these things or are somehow unaware that social interactions are becoming so detached.,"Toddlerhood is an important period in the study of attention, given the significant developmental shift in the nature of attention occurring near the end of the first year, coupled with the emergence and increased consolidation of self-regulation across early childhood .","When a child sees a parent staring at a phone or screen and then they have one stuck in front of them the child learns nothing about social interaction, except that maybe it is not important. Maybe nobody misses these things or are somehow unaware that social interactions are becoming so detached. Within 10 minutes of arriving only two were talking to each other.","The findings suggest that individual differences in focused attention evidence stability early in life but can be influenced by adult socialization. Toddlerhood is an important period in the study of attention, given the significant developmental shift in the nature of attention occurring near the end of the first year, coupled with the emergence and increased consolidation of self-regulation across early childhood . The initial attentional system reflects more automatic, orienting processes, whereas the second system, emerging near the end of the first year, is more effortfully controlled.","[5.0, 1.0, 2.0, 2.0, 1.0]",Psychology,test,1.0,news,http://guardianlv.com/2013/12/christmas-brings-apple-inc-ipad-for-babies/ 10.1177/0265407514554512,Psychology_571,There's something about seeing your partner through a camera lens that helps you refocus on just how hot they really are.,"Decomposing the interaction revealed a simple effect of the taste manipulation on perception of hypothetical relationship: Experiencing a sweet taste caused uninvolved participants to evaluate a hypothetical relationship more positively, Study 1: F(1, 151) ¼ 13.32, p < .001, Z 2 ¼ .08; Study 2: F(1, 121) ¼ 6.96, p ¼ .009, Z 2 ¼ .05, as was hypothesized.","You can start by lying together under the stars and discussing your dreams for the future, and then just let the night unfold. There's something about seeing your partner through a camera lens that helps you refocus on just how hot they really are. One bit of advice, though: Make sure you negotiate what you plan to do with the photos after, to make sure they donat get leaked or misused.","Although this main effect is inconsistent across both studies, both studies revealed the same pattern of a significant interaction between the taste manipulation and rating target (see Table 2 ). Decomposing the interaction revealed a simple effect of the taste manipulation on perception of hypothetical relationship: Experiencing a sweet taste caused uninvolved participants to evaluate a hypothetical relationship more positively, Study 1: F(1, 151) ¼ 13.32, p < .001, Z 2 ¼ .08; Study 2: F(1, 121) ¼ 6.96, p ¼ .009, Z 2 ¼ .05, as was hypothesized. In contrast, the effect of the taste manipulation was not significant on evaluations of current relationship, Fs < 1, ps > .558, Z 2 s < .01.","[2.0, 1.0, 2.0, 4.0, 2.0]",Psychology,test,2.2,news,http://ct.moreover.com/?a=34369579289&p=1pl&v=1&x=iGmNpnUsFlMTbtYLVJJxqQ 10.1038/s41398-019-0439-0,Psychology_604,"(Photo: Business Wire) The research, published in Translational Psychiatry, lays the groundwork for larger research studies to use a specific kind of electrical brain stimulation called transcranial alternating current stimulation (tACS) to treat people diagnosed with major depression.","Concurrently, we found a significant reduction in alpha power over the left frontal regions in EEG after completion of the intervention for the group that received per-protocol 10 Hz-tACS (n = 26, p < 0.05).","With a weak alternating electrical current sent through electrodes attached to the scalp, UNC School of Medicine researchers successfully targeted a naturally occurring electrical pattern in a specific part of the brain and markedly improved depression symptoms in about 70 percent of participants in a clinical study. (Photo: Business Wire) The research, published in Translational Psychiatry, lays the groundwork for larger research studies to use a specific kind of electrical brain stimulation called transcranial alternating current stimulation (tACS) to treat people diagnosed with major depression. ""Now that we've documented how this kind of tACS can reduce depression symptoms, we can fine tune our approach to help many people in a relatively inexpensive, noninvasive way.""","For the primary outcome, we did not observe a significant interaction between treatment condition (10 Hz-tACS, 40 Hz-tACS, sham) and session (baseline to 4 weeks after completion of treatment); however, exploratory analyses show that 2 weeks after completion of the intervention, the 10 Hz-tACS group had more responders (MADRS and HDRS) compared with 40 HztACS and sham groups (n = 30, p = 0.026). Concurrently, we found a significant reduction in alpha power over the left frontal regions in EEG after completion of the intervention for the group that received per-protocol 10 Hz-tACS (n = 26, p < 0.05). Our data suggest that targeting oscillations with tACS has potential as a therapeutic intervention for treatment of MDD.","[2.0, 1.0, 2.0, 2.0]",Psychology,test,1.75,news,http://ct.moreover.com/?a=38739848093&p=1pl&v=1&x=cwkZuna6lhzeU324CHbQsQ 10.1016/j.jesp.2017.10.007,Psychology_608,"It's difficult to overstate the awesome, world-changing power of the smartphone.",We pre-registered our analysis plan on OSF; see http://tinyurl.com/ z7xe43d.,"It's difficult to overstate the awesome, world-changing power of the smartphone. The sum total of human knowledge now fits in your pocket, and it comes bundled with easy access to all of your favorite people, music and photographs. No one questions a smartphone's usefulness when it's used judiciously.","The participants responded to a total of 3008 ESM surveys (68.6% of surveys sent), of which 1244 were episodes when they were interacting with others face-to-face. We pre-registered our analysis plan on OSF; see http://tinyurl.com/ z7xe43d. As predicted, during episodes that included face-to-face social interactions (N = 1244), people reported feeling more distracted when they used their smartphones than when they did not, b = 0.95, SE = 0.11, t(91.98) = 8.23 p < .001 (see Table 5 for means).","[1.0, 1.0, 1.0, 1.0, 1.0]",Psychology,test,1.0,news,http://ct.moreover.com/?a=34065361832&p=1pl&v=1&x=_XTk5cpOnYulkQ2kABL4Ww 10.1073/pnas.1407787111,Psychology_7,"Pooling more fMRI data from people with these conditions, and depression, anxiety, bipolar disorder and more could boost connectomics studies in those fields.","These results suggest maturational lag of regulatory control networks contributes to inattention and/or impulsivity across different clinical populations, and they invite new research aimed at direct comparative investigation .","Sripada also notes that connectomics could be used to examine other disorders with roots in brain connectivity - including autism, which some evidence has suggested stems from over-maturation of some brain networks, and schizophrenia, which may arise from abnormal connections. Pooling more fMRI data from people with these conditions, and depression, anxiety, bipolar disorder and more could boost connectomics studies in those fields. Of note, fMRI scans do not expose a person to radiation.","More broadly, our finding of lagged maturation of regulatory control networks in ADHD fits well with a previous study in juvenile offenders that found that relative immaturity of connectivity of motor planning regions with other brain regions, including DMN regions, predicted greater impulsivity . These results suggest maturational lag of regulatory control networks contributes to inattention and/or impulsivity across different clinical populations, and they invite new research aimed at direct comparative investigation . We also observed maturational lag in integration of the dmPFC and PCC ( Fig.","[5.0, 1.0, 1.0]",Psychology,test,1.0,news,http://www.newswise.com/articles/slow-to-mature-quick-to-distract-adhd-brain-study-finds-slower-development-of-key-connections 10.1073/pnas.1508431112,Psychology_84,"The study, which appears in the Proceedings of the National Academy of Sciences, points to a newfound role the brain's cortical oscillations play in the detection of musical sequences.",The surprising result then is that this process-the divining of temporal structure within music-facilitates pitch processing and distortion detection when such detection would seemingly have a minimal relationship to the music's temporal structure.,"The study, which appears in the Proceedings of the National Academy of Sciences, points to a newfound role the brain's cortical oscillations play in the detection of musical sequences. The findings also suggest musical training can enhance the functional role of brain rhythms. ""Specifically, our findings show that the presence of these rhythms enhances our perception of music and of pitch changes.""","Therefore, the beta activity must be predicting the timing of the notes, not of the distortion. The surprising result then is that this process-the divining of temporal structure within music-facilitates pitch processing and distortion detection when such detection would seemingly have a minimal relationship to the music's temporal structure. Accurately predicting when the beginning of the next note will come actually helps listeners to detect deviations in pitch at any point in the stimulus.","[2.0, 2.0, 4.0, 1.0, 2.0]",Psychology,test,2.2,news,http://www.futurity.org/musicians-brains-rhythms-1034492-2/ 10.1073/pnas.1407787111,Psychology_88,"""It is particularly noteworthy that the networks we found to have lagging maturation in ADHD are linked to the very behaviors that are the symptoms of ADHD,"" he says.","This analysis revealed statistically significant negative correlations for all three networks [DMN-DMN (r=-0.18; P = 0.05), DMN-FPN (r=-0.14; P = 0.02), and DMN-VAN (r=-0.21; P = 0.01); all P values from permutation tests].","These networks, and the connections between them, mature throughout early childhood all the way to young adulthood. ""It is particularly noteworthy that the networks we found to have lagging maturation in ADHD are linked to the very behaviors that are the symptoms of ADHD,"" he says. ""The results of this study set the stage for the next phase of this research, which is to examine individual components of the networks that have the maturational lag,"" he says.","or Conners' Rating Scale, 3rd Edition (39) was available for 180 (ADHD = 77) of the 421 participants in the present analysis (other participants had either different measures of ADHD symptom severity or none at all). This analysis revealed statistically significant negative correlations for all three networks [DMN-DMN (r=-0.18; P = 0.05), DMN-FPN (r=-0.14; P = 0.02), and DMN-VAN (r=-0.21; P = 0.01); all P values from permutation tests]. This result supports the hypothesis that with greater severity of inattention, there is correspondingly greater lag in maturation of DMN and its interconnections with TPNs.","[1.0, 2.0, 1.0]",Psychology,test,1.3333333333333333,news,http://www.sciencedaily.com/releases/2014/09/140915153607.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29 10.1073/pnas.1407787111,Psychology_96,"Pooling more fMRI data from people with these conditions, and depression, anxiety, bipolar disorder and more could boost connectomics studies in those fields.",These advances raise possibilities for investigating maturational lag in ADHD in the developing ICN architecture of the brain (18).,"Sripada also notes that connectomics could be used to examine other disorders with roots in brain connectivity - including autism, which some evidence has suggested stems from over-maturation of some brain networks, and schizophrenia, which may arise from abnormal connections. Pooling more fMRI data from people with these conditions, and depression, anxiety, bipolar disorder and more could boost connectomics studies in those fields. Of note, fMRI scans do not expose a person to radiation.","Our finding of maturational lag specifically in connections within and between these networks suggests a developmental etiology for the deficits proposed in these models. These advances raise possibilities for investigating maturational lag in ADHD in the developing ICN architecture of the brain (18). Thus, conventional seedbased strategies are likely to produce summary measures that do not capture underlying fine-grained patterns of variation or can miss trends that are detectable only when looking across large populations of connections.","[2.0, 2.0, 1.0, 2.0, 1.0]",Psychology,test,1.6,news,http://www.newswise.com/articles/slow-to-mature-quick-to-distract-adhd-brain-study-finds-slower-development-of-key-connections 10.1073/pnas.1407787111,Psychology_tweet_0,Lag in maturation of the brain’s intrinsic functional architecture in ADHD ,These advances raise possibilities for investigating maturational lag in ADHD in the developing ICN architecture of the brain (18).,Lag in maturation of the brain’s intrinsic functional architecture in ADHD ,"Our finding of maturational lag specifically in connections within and between these networks suggests a developmental etiology for the deficits proposed in these models. These advances raise possibilities for investigating maturational lag in ADHD in the developing ICN architecture of the brain (18). Thus, conventional seedbased strategies are likely to produce summary measures that do not capture underlying fine-grained patterns of variation or can miss trends that are detectable only when looking across large populations of connections.","[4.0, 5.0, 2.0, 3.0, 4.0]",Psychology,test,3.6,tweets,992326110741397504 10.1007/s10071-014-0794-4,Psychology_tweet_102,Speaking of shiny things: magpies are the raven antagonists... ,"We suggest that humans notice when magpies occasionally pick up shiny objects because they believe the birds find them attractive, while it goes unnoticed when magpies interact with less eye-catching items.",Speaking of shiny things: magpies are the raven antagonists... ,"Instead, all objects elicited responses indicating neophobia in free-living birds. We suggest that humans notice when magpies occasionally pick up shiny objects because they believe the birds find them attractive, while it goes unnoticed when magpies interact with less eye-catching items. The folklore may therefore result from observation bias and cultural inflation of orally transmitted episodic events.","[1.0, 1.0, 2.0, 3.0, 3.0]",Psychology,test,2.0,tweets,504340466771718144 10.1007/s10071-018-1213-z,Psychology_tweet_115,"In the first study to compare the gestural repertoire of human infants to those of other apes using a directly comparable methodological approach, researchers found that 89% of the gestures used by human infants were present in the chimpanzee repertoire. ","The single use cases would not normally be included in a gestural repertoire, see above, but are included here for completeness given the small data set.","In the first study to compare the gestural repertoire of human infants to those of other apes using a directly comparable methodological approach, researchers found that 89% of the gestures used by human infants were present in the chimpanzee repertoire. ","However, 7 of these were only coded as used in intentional communication on a single occasion, and the other 4 on n = 2 occasions. The single use cases would not normally be included in a gestural repertoire, see above, but are included here for completeness given the small data set. Given both the correlation between frequency of gesturing and number of gesture types used described above, and the correlation between the number of times a gesture occurred in a child's repertoire and its frequency in the data set (Pearson's correlation, r = 0.80, n = 51, P < 0.0001), the individual repertoires and the frequency with which a gesture was used by different children appear to be determinedly largely by sample size in our data.","[3.0, 2.0, 3.0, 1.0]",Psychology,test,2.25,tweets,1039157688268189697 10.1177/1948550614537308,Psychology_tweet_117,So in other words casual sex is great if you are a hot guy who is also an asshole. Study: ,"Hierarchical linear models (HLM) indicated that after controlling for demographics, higher sociosexuality was linked to a significantly higher likelihood of engaging in weekly casual sex, odds ratio (OR) ¼ 2.31 [1.84, 2.89], p < .001; the interaction with gender was not significant, OR ¼ 0.91 [0.74, 1.13].",So in other words casual sex is great if you are a hot guy who is also an asshole. Study: ,"Average proportion of weeks with casual sex was .09 (SD ¼ .18) per participant; 44% of those with at least one casual sex week reported only one such week (ranging 1-9 weeks). Hierarchical linear models (HLM) indicated that after controlling for demographics, higher sociosexuality was linked to a significantly higher likelihood of engaging in weekly casual sex, odds ratio (OR) ¼ 2.31 [1.84, 2.89], p < .001; the interaction with gender was not significant, OR ¼ 0.91 [0.74, 1.13]. Only 16% of those scoring below the median on sociosexuality engaged in casual sex over the 12 weeks compared to 55% of those scoring above the median.","[2.0, 1.0, 3.0, 3.0, 1.0]",Psychology,test,2.0,tweets,481601168112885760 10.1073/pnas.1407787111,Psychology_tweet_12,Maturational lag in connections within and btw functional brain networks (DMN and TPN) in ADHD via @username ,Our finding of maturational lag specifically in connections within and between these networks suggests a developmental etiology for the deficits proposed in these models.,Maturational lag in connections within and btw functional brain networks (DMN and TPN) in ADHD via @username ,"In particular, lag was observed within the midline core of the DMN, as well as in DMN connections with right lateralized prefrontal regions (in frontoparietal network) and anterior insula (in ventral attention network). Our finding of maturational lag specifically in connections within and between these networks suggests a developmental etiology for the deficits proposed in these models. These advances raise possibilities for investigating maturational lag in ADHD in the developing ICN architecture of the brain (18).","[3.0, 3.0, 2.0, 3.0, 4.0]",Psychology,test,3.0,tweets,511900529182928896 10.1177/1948550614537308,Psychology_tweet_120,Thosewho were sociosexually unrestricted reported lower stress and greater overall emotional health after casual sex  ,"Simple slope analyses indicated that high-SOI participants who had casual sex over the academic year had higher self-esteem (B ¼ 0.14, SE ¼ 0.06, p ¼ .025) and marginally lower depression (B ¼ À0.12, SE ¼ 0.07, p ¼ .091) and anxiety (B ¼ À0.11, SE ¼ 0.06, p ¼ .086) than high-SOI participants who did not have casual sex (Figure 3) .",Thosewho were sociosexually unrestricted reported lower stress and greater overall emotional health after casual sex  ,"The critical interaction term was significant for all three assessed outcomes (all ps < .05). Simple slope analyses indicated that high-SOI participants who had casual sex over the academic year had higher self-esteem (B ¼ 0.14, SE ¼ 0.06, p ¼ .025) and marginally lower depression (B ¼ À0.12, SE ¼ 0.07, p ¼ .091) and anxiety (B ¼ À0.11, SE ¼ 0.06, p ¼ .086) than high-SOI participants who did not have casual sex (Figure 3) . Among low-SOI participants, those who had casual sex did not differ significantly from those who did not have casual sex on self-esteem (B ¼ À0.10, SE ¼ 0.07, p ¼ .168), depression (B ¼ 0.13, SE ¼ 0.08, p ¼ .104), or anxiety (B ¼ 0.11, SE ¼ 0.07, p ¼ .130).","[5.0, 3.0, 5.0, 4.0, 5.0]",Psychology,test,4.4,tweets,481621431529504768 10.1177/0956797618813092,Psychology_tweet_132,"oh dear, more unconscious biases .. Revealing Hidden #Gender Biases in Competence Impressions of Faces ","Thus, the results show that confidence and masculinity cues are important ingredients of competence impressions-ingredients that cannot be explained as a by-product of attractiveness.","oh dear, more unconscious biases .. Revealing Hidden #Gender Biases in Competence Impressions of Faces ","It follows that the variance in the competence impressions cannot be attributed to the halo effect of attractiveness, which is a significant natural confound of competence impressions. Thus, the results show that confidence and masculinity cues are important ingredients of competence impressions-ingredients that cannot be explained as a by-product of attractiveness. Masculinity cues are strongly related to perceptions of gender, which suggests the presence of gender biases in competence impressions.","[3.0, 3.0, 2.0, 2.0]",Psychology,test,2.5,tweets,1071368900485492741 10.1038/s41598-018-26821-7,Psychology_tweet_133,"Differentiating attention control in autistic traits and psychosis-proneness. Great work @username et al, congrats! ","Independent of task, we show that the direction of the effect of autism or psychosis traits on the suppression or rejection of a non-target item is diametrical.","Differentiating attention control in autistic traits and psychosis-proneness. Great work @username et al, congrats! ","Our capacity to attend a target while ignoring irrelevant distraction impacts our ability to successfully interact with our environment. Independent of task, we show that the direction of the effect of autism or psychosis traits on the suppression or rejection of a non-target item is diametrical. In Study 1, in which the presence of a salient non-target item hindered performance, higher autism traits were associated with better performance, while higher psychosis traits were associated with worse performance.","[4.0, 3.0, 2.0, 2.0, 4.0]",Psychology,test,3.0,tweets,1002144037153882112 10.1371/journal.pone.0073791,Psychology_tweet_139,A new scientific study reveals what words men and women use the most on Facebook. We definitely see some themes. <3 ,Gender provides a familiar and easy to understand proof of concept for open-vocabulary analysis.,A new scientific study reveals what words men and women use the most on Facebook. We definitely see some themes. <3 ,"This is not too surprising since openness exhibits the most variation across conditions of other studies (for examples, see ), and its component traits are most loosely related . Gender provides a familiar and easy to understand proof of concept for open-vocabulary analysis. All results are significant at Bonferroni-corrected pv0:001.","[2.0, 1.0, 3.0]",Psychology,test,2.0,tweets,385440869454987264 10.1177/0013916516628178,Psychology_tweet_147,Kitchen clutter and chaos linked to overeating. ,"In the context of the chaotic environment combined with an out-of-control mindset, increased cookie consumption might have been the result of depleted selfregulatory strength from managing one's emotions under such conditions.",Kitchen clutter and chaos linked to overeating. ,"Because sweet foods are generally seen as being ""forbidden"" foods , some degree of effort was perhaps needed to resist eating too many cookies. In the context of the chaotic environment combined with an out-of-control mindset, increased cookie consumption might have been the result of depleted selfregulatory strength from managing one's emotions under such conditions. Of course, future research is needed to directly test this hypothesis.","[5.0, 4.0, 4.0, 1.0]",Psychology,test,4.0,tweets,699291541081198592 10.1073/pnas.1407787111,Psychology_tweet_155,'Lag in maturation of the brain’s intrinsic functional architecture in ADHD' ,Visualization of the pattern of altered connections revealed prominent lag in segregation between anterior insula in VAN and PCC in DMN.,'Lag in maturation of the brain’s intrinsic functional architecture in ADHD' ,"The odds that a strongly maturing connection was lagged (vs. being unlagged) were 2.21 to 1, which is statistically significant (P < 0.03; permutation test). Visualization of the pattern of altered connections revealed prominent lag in segregation between anterior insula in VAN and PCC in DMN. or Conners' Rating Scale, 3rd Edition (39) was available for 180 (ADHD = 77) of the 421 participants in the present analysis (other participants had either different measures of ADHD symptom severity or none at all).","[3.0, 2.0, 2.0, 2.0]",Psychology,test,2.25,tweets,511971214219542528 10.1073/pnas.1407787111,Psychology_tweet_157,Lag in maturation of the brain’s intrinsic functional architecture in ADHD in PNAS. ,"This regression modeling yielded two comprehensive maps of effect of age and effect of ADHD, respectively.",Lag in maturation of the brain’s intrinsic functional architecture in ADHD in PNAS. ,"Our results invite further investigation into the neurobiological mechanisms in ADHD that produce delays in development of large-scale networks. This regression modeling yielded two comprehensive maps of effect of age and effect of ADHD, respectively. Examining patterns of spatial correspondence across populations of connections in these whole-cortex connectomic maps provides a powerful way to investigate the maturational lag hypothesis.","[3.0, 3.0, 2.0, 2.0]",Psychology,test,2.5,tweets,967789838752677888 10.1073/pnas.1508431112,Psychology_tweet_166,More research on entrainment/decoding that supports music-based interventions for reading ability. ,"Building on effects such as these, we expect that increased entrainment and reliability in musicians' cortical responses may reflect expertise.",More research on entrainment/decoding that supports music-based interventions for reading ability. ,"Furthermore, prestimulus beta plays a role in generating accurate temporal predictions even in pure listening tasks (9). Building on effects such as these, we expect that increased entrainment and reliability in musicians' cortical responses may reflect expertise. This methodological choice allows us to study the rate of the music without delving into the complexities of beat and meter, which can shift nonmonotonically with increasing overall rate (i.e., faster notes are often arranged into larger groupings).","[3.0, 2.0, 1.0, 2.0, 4.0]",Psychology,test,2.4,tweets,659189346445213697 10.1177/1948550614537308,Psychology_tweet_17,Casual sex is good for Health ,Average proportion of weeks with casual sex was .09 (SD ¼ .18) per participant; 44% of those with at least one casual sex week reported only one such week (ranging 1-9 weeks).,Casual sex is good for Health ,"At least 1 week with casual sex was reported by 80 (35%) participants; these percentages were similar in both sexes, w 2 (1) < 1. Average proportion of weeks with casual sex was .09 (SD ¼ .18) per participant; 44% of those with at least one casual sex week reported only one such week (ranging 1-9 weeks). Hierarchical linear models (HLM) indicated that after controlling for demographics, higher sociosexuality was linked to a significantly higher likelihood of engaging in weekly casual sex, odds ratio (OR) ¼ 2.31 [1.84, 2.89], p < .001; the interaction with gender was not significant, OR ¼ 0.91 [0.74, 1.13].","[3.0, 3.0, 2.0, 3.0]",Psychology,test,2.75,tweets,481813995460890624 10.1007/s10071-014-0832-2,Psychology_tweet_178,Are cats listening to owners? #springerlink,"However, overall, cats in the negative group were significantly more likely to gaze alternate between the screen and the fan than cats in the positive group (glm z = 3.9, P \ 0.001).",Are cats listening to owners? #springerlink,"There was no effect of phase (glm z = 1.7, P = 0.09) and no interaction (glm z = 0.46, P = 0.64) between phase and group on the likelihood of cats showing gaze alternation between the screen and the fan. However, overall, cats in the negative group were significantly more likely to gaze alternate between the screen and the fan than cats in the positive group (glm z = 3.9, P \ 0.001). Results showed no interaction between group and phase (glm Phase 2 z = 1.69, P = 0.09; Phase 3 z = 1.22, P = 0.22; Phase 4 z = 0.42, P = 0.67), but a main effect of both group (glm z = 4.43, P \ 0.001) and phase with cats alternating their gaze significantly less between the screen and the fan in Phase 4 than Phase 1 (glm Phase 4 z = 5.7 P \ 0.001; Phase 2 z = 1.7 P = 0.08; Phase 3 z = 0.02, P = 0.9), and cats in the positive group alternating their gaze between the screen and the fan significantly less than cats in the negative group.","[3.0, 1.0, 2.0, 3.0]",Psychology,test,2.25,tweets,554657182818398208 10.1111/jopy.12047,Psychology_tweet_184,"When the Going Gets Tough: The ""Why” of Goal Striving Matters. An excellent article by @username + colleagues. ","Practitioners who aim to facilitate effective goal setting in sport, business, and educational settings would benefit from guidelines for developing autonomous motivation.","When the Going Gets Tough: The ""Why” of Goal Striving Matters. An excellent article by @username + colleagues. ","Such motivation can be beneficial, behaviorally and affectively, especially when goals become increasingly difficult over time. Practitioners who aim to facilitate effective goal setting in sport, business, and educational settings would benefit from guidelines for developing autonomous motivation. To conclude, the present research supports and extends previous findings regarding the role of autonomous motivation for adaptive goal striving.","[4.0, 3.0, 3.0, 3.0, 5.0]",Psychology,test,3.6,tweets,367279875989573632 10.1073/pnas.1612881114,Psychology_tweet_191,Interesting study indicates that we're born with a basic understanding of colour. ,"There was firm support for H1 for the large red/yellow pair (7.5RP-10Y, columns 38-12), t (9) =2.84, p=.02, B=6.30E+00 and for H0 for the larger hue differences within green (7.5GY-2.5BG, columns 24-30) or blue (10BG-5PB, columns 15-21), (largest t=1.34, smallest p=0.21, largest B=0.17).",Interesting study indicates that we're born with a basic understanding of colour. ,"). There was firm support for H1 for the large red/yellow pair (7.5RP-10Y, columns 38-12), t (9) =2.84, p=.02, B=6.30E+00 and for H0 for the larger hue differences within green (7.5GY-2.5BG, columns 24-30) or blue (10BG-5PB, columns 15-21), (largest t=1.34, smallest p=0.21, largest B=0.17). We identify stimulus 10Y, 2.5Y and 7.5GY as 'yellow' here due to Munsell hue notation, although at the munsell value sampled, these hues are darker than prototypical yellow.","[3.0, 1.0, 2.0, 1.0, 3.0]",Psychology,test,2.0,tweets,861731769808289792 10.1073/pnas.1407787111,Psychology_tweet_201,"Kids w/ #ADHD have less-mature brain networks for internal, external tasks HT @username ","We found prominent maturational lag in DMN interconnections with VAN, with a concentration of lagged connections involving anterior insula, a key hub in VAN.","Kids w/ #ADHD have less-mature brain networks for internal, external tasks HT @username ","Our results thus add to this network regulation model of ADHD by suggesting a developmental explanation for the observed pattern of network and regional abnormalities. We found prominent maturational lag in DMN interconnections with VAN, with a concentration of lagged connections involving anterior insula, a key hub in VAN. These observations suggest that lagged maturation in anterior insula could contribute to several forms of inattention in ADHD.","[1.0, 4.0, 1.0]",Psychology,test,1.0,tweets,512221260479483904 10.1002/icd.580,Psychology_tweet_216,Focused Attention in Toddlers ,"Toddlerhood is an important period in the study of attention, given the significant developmental shift in the nature of attention occurring near the end of the first year, coupled with the emergence and increased consolidation of self-regulation across early childhood .",Focused Attention in Toddlers ,"The findings suggest that individual differences in focused attention evidence stability early in life but can be influenced by adult socialization. Toddlerhood is an important period in the study of attention, given the significant developmental shift in the nature of attention occurring near the end of the first year, coupled with the emergence and increased consolidation of self-regulation across early childhood . The initial attentional system reflects more automatic, orienting processes, whereas the second system, emerging near the end of the first year, is more effortfully controlled.","[3.0, 2.0, 1.0, 4.0]",Psychology,test,2.5,tweets,1072536079159451648 10.1177/1948550614537308,Psychology_tweet_22,Casual sex is good for your self-esteem. So says study. ,These results integrate within a personality framework prior findings of more positive emotional reactions following casual sex among those with greater interest in or approval of casual sex and lower well-being among those who engage in it for nonautonomous reasons .,Casual sex is good for your self-esteem. So says study. ,"Typically, sociosexually unrestricted individuals (i.e., those highly oriented toward casual sex) reported lower distress and higher thriving following casual sex, suggesting that high sociosexuality may both buffer against any potentially harmful consequences of casual sex and allow access to its potential benefits. These results integrate within a personality framework prior findings of more positive emotional reactions following casual sex among those with greater interest in or approval of casual sex and lower well-being among those who engage in it for nonautonomous reasons . Consistent with theoretical perspectives and research emphasizing Anxiety p = .014 ns Figure 2 .","[4.0, 3.0, 4.0, 3.0, 2.0]",Psychology,test,3.2,tweets,480844901848858624 10.1093/geronb/gbw112,Psychology_tweet_228,"From Journals of Gerontology: Series B: ""Chronic Stress and Negative Marital Quality Among Older Couples: ..."" ","Likewise, husbands' greater chronic stress exposure was associated with increased waist circumference among wives when husbands reported higher negative marital quality.","From Journals of Gerontology: Series B: ""Chronic Stress and Negative Marital Quality Among Older Couples: ..."" ","Wives' greater chronic stress exposure was associated with increased waist circumference among husbands when husbands reported higher negative marital quality. Likewise, husbands' greater chronic stress exposure was associated with increased waist circumference among wives when husbands reported higher negative marital quality. In contrast, wives' greater chronic stress exposure was associated with increased waist circumference among husbands when wives' reported lower negative marital quality.","[3.0, 3.0, 4.0]",Psychology,test,3.333333333333333,tweets,783846853431263232 10.1073/pnas.1407787111,Psychology_tweet_23,Lag in maturation of the brain’s intrinsic functional architecture in... ,We found significant and specific maturational lag in connections within default mode network (DMN) and in DMN interconnections with two task positive networks (TPNs): frontoparietal network and ventral attention network.,Lag in maturation of the brain’s intrinsic functional architecture in... ,"We found significant and specific maturational lag in connections within default mode network (DMN) and in DMN interconnections with two task positive networks (TPNs): frontoparietal network and ventral attention network. In particular, lag was observed within the midline core of the DMN, as well as in DMN connections with right lateralized prefrontal regions (in frontoparietal network) and anterior insula (in ventral attention network). Our finding of maturational lag specifically in connections within and between these networks suggests a developmental etiology for the deficits proposed in these models.","[4.0, 5.0, 5.0, 3.0, 2.0]",Psychology,test,3.8,tweets,517266214385893376 10.3102/0002831214544298,Psychology_tweet_238,Interesting study teasing out contradictory hypotheses within the research literature on college selectivity | ,"However, as this article shows, merely attending a more selective college does not make much of a difference for a given student's chances of graduating if all else remains the same.",Interesting study teasing out contradictory hypotheses within the research literature on college selectivity | ,"It is possible that colleges with low graduation rates can make some institutional changes to help their students stay in college and complete their studies. However, as this article shows, merely attending a more selective college does not make much of a difference for a given student's chances of graduating if all else remains the same. We find at best weak evidence that institutions raise, via academic selectivity, the graduation rates of students who otherwise would have lower chances of graduating.","[4.0, 3.0, 2.0, 3.0, 4.0]",Psychology,test,3.2,tweets,497437549845950464 10.1177/0265407514554512,Psychology_tweet_252,New Year message: A sweet taste influences your romantic perceptions! Amusing psychology paper.,"Decomposing the interaction revealed a simple effect of the taste manipulation on perception of hypothetical relationship: Experiencing a sweet taste caused uninvolved participants to evaluate a hypothetical relationship more positively, Study 1: F(1, 151) ¼ 13.32, p < .001, Z 2 ¼ .08; Study 2: F(1, 121) ¼ 6.96, p ¼ .009, Z 2 ¼ .05, as was hypothesized.",New Year message: A sweet taste influences your romantic perceptions! Amusing psychology paper.,"Although this main effect is inconsistent across both studies, both studies revealed the same pattern of a significant interaction between the taste manipulation and rating target (see Table 2 ). Decomposing the interaction revealed a simple effect of the taste manipulation on perception of hypothetical relationship: Experiencing a sweet taste caused uninvolved participants to evaluate a hypothetical relationship more positively, Study 1: F(1, 151) ¼ 13.32, p < .001, Z 2 ¼ .08; Study 2: F(1, 121) ¼ 6.96, p ¼ .009, Z 2 ¼ .05, as was hypothesized. In contrast, the effect of the taste manipulation was not significant on evaluations of current relationship, Fs < 1, ps > .558, Z 2 s < .01.","[3.0, 4.0, 2.0, 3.0, 4.0]",Psychology,test,3.2,tweets,550041326583308288 10.1016/j.biopsych.2018.12.023,Psychology_tweet_254,Even more reason to invest in #SDOH and early childhood: adverse events in the first three years of life can have profound effects on the developing brain @username,These results suggest that the SLCMA allowed us to more effectively identify methylation differences among children with and without a history of exposure to adversity.,Even more reason to invest in #SDOH and early childhood: adverse events in the first three years of life can have profound effects on the developing brain @username,"Similarly, the top CpG site in the SLCMA (cg19157140), which suggested a sensitive period at age 1.75 associated with the effects of neighborhood disadvantage, was nonsignificant in the corresponding EWAS ( =0.001; p=0.0002; Figure 5 ). These results suggest that the SLCMA allowed us to more effectively identify methylation differences among children with and without a history of exposure to adversity. There was no evidence in support of compound theoretical models, whereby more than one theoretical model explained the most outcome variability.","[2.0, 4.0, 3.0]",Psychology,test,3.0,tweets,1108761542697406465 10.1016/j.neurobiolaging.2010.10.006,Psychology_tweet_271,Dietary ketosis can improve memory ,"Should this approach prove to be effective and to have benefit beyond the period of intervention, it might be applied intermittently as a preventive strategy, an approach that would mitigate many concerns about chronic, severe carbohydrate restriction.",Dietary ketosis can improve memory ,"Also, demonstrating and distinguishing mechanisms of neural action including metabolic changes and neuroprotective factors in conjunction with neurocognitive effects will be of particular interest and should have implications for understanding the etiology of neurodegeneration. A prominent issue will be duration of the effects and whether there is persistence of benefit beyond the period of active intervention. Should this approach prove to be effective and to have benefit beyond the period of intervention, it might be applied intermittently as a preventive strategy, an approach that would mitigate many concerns about chronic, severe carbohydrate restriction.","[2.0, 4.0, 1.0, 2.0]",Psychology,test,2.25,tweets,236106592842567680 10.1016/j.neuron.2015.03.023,Psychology_tweet_278,Check out our latest work on neural mechanisms that help parse heterogeneity in early language development in #autism ,"Comparing these different classifiers based on area under the curve (AUC) values, we find that the multimodal combination of clinical intake measures plus left hemisphere superior temporal cortex activation outperformed all other classifiers (AUC = 81).",Check out our latest work on neural mechanisms that help parse heterogeneity in early language development in #autism ,"In ASD Good, however, this atypical reversal was less severe when assessing the brain-outcome behavioral relationship, and this may be indicative of a different developmental process emerging in ASD Good that allows such brain-behavioral relationships to approach those seen in LD/DD. Comparing these different classifiers based on area under the curve (AUC) values, we find that the multimodal combination of clinical intake measures plus left hemisphere superior temporal cortex activation outperformed all other classifiers (AUC = 81). Classifiers that used either ADOS alone, clinical intake measures alone, or fMRI alone performed similarly in terms of near-identical AUC values (AUC ranging from 67 to 70) (see Figure 5 ).","[2.0, 2.0, 2.0, 3.0]",Psychology,test,2.25,tweets,586231711081586688 10.1001/jamapsychiatry.2014.3039,Psychology_tweet_28,DBT for High Suicide Risk in Borderline Personality Disorder ,"Thus, all 3 versions of DBT were comparably effective at reducing suicidality among individuals at high risk for suicide.",DBT for High Suicide Risk in Borderline Personality Disorder ,"Contrary to our expectations, standard DBT was not superior to either comparison condition for any suicide-related outcome, and no significant differences were detected between DBT-S and DBT-I. Thus, all 3 versions of DBT were comparably effective at reducing suicidality among individuals at high risk for suicide. In contrast, findings suggested that DBT interventions that included DBT skills training (standard DBT and DBT-S) were more effective in reducing NSSI acts and improving other mental health problems than a DBT intervention without skills training (DBT-I).","[4.0, 4.0, 3.0, 4.0]",Psychology,test,3.75,tweets,580793363378630656 10.1126/science.1224000,Psychology_tweet_285,Oscillatory synchronization during visual working memory. ,"However, the majority of spikefield interactions involving identity selective units come from cells recorded in areas LIP, PG and to a lesser extent MIP.",Oscillatory synchronization during visual working memory. ,"(PFC unit -PPC lfp pairs were not included due to small sample sizes.) However, the majority of spikefield interactions involving identity selective units come from cells recorded in areas LIP, PG and to a lesser extent MIP. Our findings demonstrate that fronto-parietal synchronization during visual working memory is widespread, task-dependent and content specific during the delay period.","[1.0, 5.0, 1.0, 2.0, 1.0]",Psychology,test,1.0,tweets,265149987107778560 10.1177/0956797613489890,Psychology_tweet_292,"@username @username @username your guess is just right. Vicarious extinction works better as compared to direct extinction (behaviour: fMRI: ). and indeed, we could have been more generous with the space between brackets!","It can be speculated that this process involves the top-down impact on the amygdala by the dorsal mPFC in concert with other prefrontal regions, including the vmPFC, and memoryrelated regions in the hippocampal complex.","@username @username @username your guess is just right. Vicarious extinction works better as compared to direct extinction (behaviour: fMRI: ). and indeed, we could have been more generous with the space between brackets!","In our paradigm, watching the calm learning model during extinction might have imbued the CS+ with a safety value resulting in the abolished return of fear during the reinstatement-test stage. It can be speculated that this process involves the top-down impact on the amygdala by the dorsal mPFC in concert with other prefrontal regions, including the vmPFC, and memoryrelated regions in the hippocampal complex. The potency of vicarious extinction in our study is conceptually similar to earlier work in monkeys showing that observing a fearless learning model can cause latent inhibition or ""immunization"" against subsequent fear learning .","[1.0, 1.0, 1.0, 1.0]",Psychology,test,1.0,tweets,935094519909027840 10.1111/jcpp.12015,Psychology_tweet_3,"@username ""Th absence of a gestational connection to th mother may be more problematic ... than th absence of a genetic link"" ",Conclusions: The absence of a gestational connection to the mother may be more problematic for children than the absence of a genetic link.,"@username ""Th absence of a gestational connection to th mother may be more problematic ... than th absence of a genetic link"" ","However, maternal distress had a more negative impact on children who were aware of their origins. Conclusions: The absence of a gestational connection to the mother may be more problematic for children than the absence of a genetic link. When the mother's egg and father's sperm are used in IVF and the mother undergoes the pregnancy, the parents have both a genetic and gestational link to the child in the same way as parents of naturally conceived children.","[5.0, 5.0, 5.0, 5.0, 5.0]",Psychology,test,5.0,tweets,881660102633238531 10.1073/pnas.1407787111,Psychology_tweet_38,Lag in maturation of the brain’s intrinsic functional architecture in ADHD disorder ,These observations suggest that lagged maturation in anterior insula could contribute to several forms of inattention in ADHD.,Lag in maturation of the brain’s intrinsic functional architecture in ADHD disorder ,"We found prominent maturational lag in DMN interconnections with VAN, with a concentration of lagged connections involving anterior insula, a key hub in VAN. These observations suggest that lagged maturation in anterior insula could contribute to several forms of inattention in ADHD. There was also a lag in ADHD in integration of interconnections linking DMN and FPN (Fig.","[5.0, 5.0, 4.0, 3.0, 4.0]",Psychology,test,4.2,tweets,738780468573831169 10.1016/j.bbi.2011.08.007,Psychology_tweet_45,Immune dysfunction in autism. Pathophysiological pathways. ,"Furthermore, these dysfunctional immune responses are associated with increased impairments in behaviors characteristic of core features of ASD, in particular, deficits in social interactions and communication.",Immune dysfunction in autism. Pathophysiological pathways. ,"Furthermore, these dysfunctional immune responses are associated with increased impairments in behaviors characteristic of core features of ASD, in particular, deficits in social interactions and communication. This review will discuss the current state of our knowledge of immune dysfunction in ASD, how these findings may impact on underlying neuro-immune mechanisms and implicate potential areas where the manipulation of the immune response could have an impact on behavior and immunity in ASD. There is a concordance rate for ASD of 0-37% reported for dizygotic twins, while concordance rates of 44-91% are reported for monozygotic twins (Bailey et al., 1995; Constantino and Todd, 2000; Kates et al., 2004; Steffenburg et al., 1989) , suggesting that genetic composition may contribute to increased risk of developing ASD.","[3.0, 4.0, 3.0, 4.0]",Psychology,test,3.5,tweets,264799278818533376 10.1177/1948550617725152,Psychology_tweet_59,"Extraverted and conscientious adults exhibit a faster walking speed, while neurotics go slower. ","Across most samples and in a meta-analysis, lower neuroticism and higher extraversion, conscientiousness, and openness at baseline were prospectively related to faster gait speed.","Extraverted and conscientious adults exhibit a faster walking speed, while neurotics go slower. ","Across most samples and in a meta-analysis, lower neuroticism and higher extraversion, conscientiousness, and openness at baseline were prospectively related to faster gait speed. In the HRS, lower neuroticism and higher extraversion, conscientiousness, and openness were related to slower gait speed decline. This study provides robust evidence that walking speed in adulthood reflects, in part, the individual's personality.","[3.0, 4.0, 5.0, 3.0, 3.0]",Psychology,test,3.6,tweets,902458072114888704 10.1177/0956797619838762,Psychology_tweet_60,"Recent @username paper with @username now available online! Head tilt is an action unit imposter -- a downwards head tilt increases perceptions of dominance by mimicking the appearance cues associated with corrugator (AU4) activation. ","Finally, the indirect effect of head tilt on perceptions of dominance via eyebrow V-shape was significant, b =.16, p < .01, 95% CI [.11 to .22].","Recent @username paper with @username now available online! Head tilt is an action unit imposter -- a downwards head tilt increases perceptions of dominance by mimicking the appearance cues associated with corrugator (AU4) activation. ","The direct effect of head tilt on perceptions of dominance while controlling for eyebrow V-shape was significant but partially attenuated, b = .17, t = 3.26, p < .001, 95% CI: [.07 to .27]. Finally, the indirect effect of head tilt on perceptions of dominance via eyebrow V-shape was significant, b =.16, p < .01, 95% CI [.11 to .22]. Follow-up models outlining the a and b pathways while estimating additional random slopes and covariates, or using different analyses (e.g., repeated measures ANOVA), did not change the statistical significance or the direction of other pathways in the model (see Table 1 and SOM-U).","[5.0, 4.0, 4.0, 3.0, 3.0]",Psychology,test,3.8,tweets,1120854997497860096 10.1038/s41398-019-0439-0,Psychology_tweet_64,"Double-blind placebo controlled #tACS trial for treatment of major depressive disorder. Response rates: 10Hz-tACS: 78% versus 40Hz-tACS: 30%, versus sham-tACS: 20%. Significant suppression of left frontal alpha. Work by Morgan Alexander & @username. ","Concurrently, we found a significant reduction in alpha power over the left frontal regions in EEG after completion of the intervention for the group that received per-protocol 10 Hz-tACS (n = 26, p < 0.05).","Double-blind placebo controlled #tACS trial for treatment of major depressive disorder. Response rates: 10Hz-tACS: 78% versus 40Hz-tACS: 30%, versus sham-tACS: 20%. Significant suppression of left frontal alpha. Work by Morgan Alexander & @username. ","For the primary outcome, we did not observe a significant interaction between treatment condition (10 Hz-tACS, 40 Hz-tACS, sham) and session (baseline to 4 weeks after completion of treatment); however, exploratory analyses show that 2 weeks after completion of the intervention, the 10 Hz-tACS group had more responders (MADRS and HDRS) compared with 40 HztACS and sham groups (n = 30, p = 0.026). Concurrently, we found a significant reduction in alpha power over the left frontal regions in EEG after completion of the intervention for the group that received per-protocol 10 Hz-tACS (n = 26, p < 0.05). Our data suggest that targeting oscillations with tACS has potential as a therapeutic intervention for treatment of MDD.","[2.0, 3.0, 4.0, 3.0]",Psychology,test,3.0,tweets,1103041532511309825 10.1001/jamapsychiatry.2014.1126,Psychology_tweet_66,Poor #sleep quality increases chances of #suicide. ,"This demonstrates the importance of assessing disturbed sleep in the presence of other, well-established and robust risk factors for suicide.",Poor #sleep quality increases chances of #suicide. ,"Our results nevertheless indicated that the endorsement of higher depressive symptoms and sleep disturbances yielded greatest risk for death by suicide. This demonstrates the importance of assessing disturbed sleep in the presence of other, well-established and robust risk factors for suicide. The present study contributes to the extant literature in several ways.","[5.0, 5.0, 5.0, 5.0]",Psychology,test,5.0,tweets,500668324104388609 10.1073/pnas.1407787111,Psychology_tweet_75,Kids with ADHD have brains that lag in maturation. ,Our results invite further investigation into the neurobiological mechanisms in ADHD that produce delays in development of large-scale networks.,Kids with ADHD have brains that lag in maturation. ,Our results provide strong initial evidence that these alterations arise from delays in typical maturational patterns. Our results invite further investigation into the neurobiological mechanisms in ADHD that produce delays in development of large-scale networks. We found significant and specific maturational lag in connections within default mode network (DMN) and in DMN interconnections with two task positive networks (TPNs): frontoparietal network and ventral attention network.,"[3.0, 4.0, 5.0]",Psychology,test,4.0,tweets,512042206815739905 10.1111/jcpp.12015,Psychology_tweet_87,New study tracks emotional health of 'surrogate kids'   - Link to Abstract: #surrogacy,This may also be true of surrogacy children who similarly have to face up to being different at an early age.,New study tracks emotional health of 'surrogate kids'   - Link to Abstract: #surrogacy,"Interestingly, the adopted children's behavior problems had reduced by adolescence , as had the behavior problems of the surrogacy children in the present study by age 10. suggested that internationally adopted children struggle with identity issues earlier than domestically adopted children due to their difference in appearance from their parents. This may also be true of surrogacy children who similarly have to face up to being different at an early age. Although the sample sizes were not large and thus small differences between family types may not have been detected, an advantage of the study was that data were collected before the children were aware of their biological origins, allowing the consequences of secrecy versus openness about the nature of their birth to be examined prospectively.","[4.0, 4.0, 2.0, 3.0, 3.0]",Psychology,test,3.2,tweets,347365689499201536 10.1177/1948550614537308,Psychology_easy_7,"""Typically, sociosexually unrestricted individuals (i.e., those highly oriented toward casual sex) reported lower distress and higher thriving following casual sex, suggesting that high sociosexuality may both buffer against any potentially harmful consequences of casual sex and allow access to its potential benefits,"" the researchers write.","Typically, sociosexually unrestricted individuals (i.e., those highly oriented toward casual sex) reported lower distress and higher thriving following casual sex, suggesting that high sociosexuality may both buffer against any potentially harmful consequences of casual sex and allow access to its potential benefits.","When it came to those who were sociosexually unrestricted, having casual sex was associated with higher self-esteem and life satisfaction and lower depression and anxiety. ""Typically, sociosexually unrestricted individuals (i.e., those highly oriented toward casual sex) reported lower distress and higher thriving following casual sex, suggesting that high sociosexuality may both buffer against any potentially harmful consequences of casual sex and allow access to its potential benefits,"" the researchers write. Additionally, feelings of authenticity ""amplified"" the beneficial psychological effects, but did not spur them, as hypothesized.","Instead, support was found for the hypothesized interaction with sociosexuality for most well-being indicators across all analyses, suggesting the effects of casual sex depend on the extent to which this behavior is congruent with one's general personality tendencies and reproductive strategies. Typically, sociosexually unrestricted individuals (i.e., those highly oriented toward casual sex) reported lower distress and higher thriving following casual sex, suggesting that high sociosexuality may both buffer against any potentially harmful consequences of casual sex and allow access to its potential benefits. These results integrate within a personality framework prior findings of more positive emotional reactions following casual sex among those with greater interest in or approval of casual sex and lower well-being among those who engage in it for nonautonomous reasons .",[5],Psychology,test,5.0,news,http://www.psmag.com/navigation/health-and-behavior/casual-sex-excellent-people-love-casual-sex-83847/ 10.1073/pnas.1508431112,Psychology_easy_18,"Moreover, musicians much more accurately detected pitch distortions--as evidenced by corresponding cortical oscillations.","A similar effect could be occurring in musicians where training manifests structural and functional changes, presumably, to optimize processing and production of musical stimuli.","This difference, the researchers say, may suggest that non-musicians are unable to process the music as a continuous melody rather than as individual notes. Moreover, musicians much more accurately detected pitch distortions--as evidenced by corresponding cortical oscillations. Brain rhythms, they add, therefore appear to play a role in parsing and grouping sound streams into ""chunks"" that are then analyzed as speech or music.","This suggests a communication-throughcoherence mechanism in which relevant brain regions gain access to the stimulus by entraining to the parsing mechanism. A similar effect could be occurring in musicians where training manifests structural and functional changes, presumably, to optimize processing and production of musical stimuli. Further experiments will be required to dissociate between these hypotheses.",[1],Psychology,test,1.0,news,http://www.futurity.org/musicians-brains-rhythms-1034492-2/ 10.1073/pnas.1508431112,Psychology_easy_31,"This difference, the researchers say, may suggest that non-musicians are unable to process the music as a continuous melody rather than as individual notes.",This marks a stark contrast with nonmusicians and may suggest that musical training extends the frequency limit of cortical tracking.,"Only musicians, however, showed oscillations that synchronized with unusually slow clips. This difference, the researchers say, may suggest that non-musicians are unable to process the music as a continuous melody rather than as individual notes. Moreover, musicians much more accurately detected pitch distortions--as evidenced by corresponding cortical oscillations.","The musicians did show significant entrainment at 0.7 Hz for the corresponding stimuli. This marks a stark contrast with nonmusicians and may suggest that musical training extends the frequency limit of cortical tracking. However, comparing above and below 1 nps (as in experiments 1 and 2) still showed a significant increase above 1 nps (experiment 3, T = 2.44, P < 0.05), suggesting musicians were better at entraining to the higher frequencies.",[1],Psychology,test,1.0,news,http://www.futurity.org/musicians-brains-rhythms-1034492-2/ 10.1177/1948550614537308,Psychology_easy_68,"Even though these study's findings contradicted other study's findings, they explain that their study found positive effects of having casual sex for people who wanted to engage in it in the first place.","In general, self-congruency can be expected to affect both men and women.","They also reported having less stress and better emotional health. Even though these study's findings contradicted other study's findings, they explain that their study found positive effects of having casual sex for people who wanted to engage in it in the first place. The researchers added that if people do not have casual sex for the right reasons, the activity could result in negative consequences.","To the extent that casual sex represents an authentic and self-congruent pursuit for unrestricted individuals, but an unauthentic, self-discrepant pursuit for restricted individuals, casual sex would be a beneficial experience for the former, but a harmful experience for the latter. In general, self-congruency can be expected to affect both men and women. A total of 872 students completed the 35-min, online questionnaire at baseline (13.4% response rate); 560 students were reassessed at the end of the academic year (64% retention rate).",[1],Psychology,test,1.0,news,http://www.counselheal.com/articles/10249/20140626/casual-sex-can-be-good-study-reports.htm 10.1111/desc.12179,Psychology_easy_69,"For instance, the difference between search times, with and without naming the target object, indicate a key role for a kind of brief visual memory known as working memory, that helps us remember what we just saw as we look to something new.",Figure 2A depicts mean RT for the Silent and the Label conditions as a function of distractor set size.,"Vales said their research results ""begin to tell us precisely how words help, the kinds of cognitive processes words tap into to change how children behave. For instance, the difference between search times, with and without naming the target object, indicate a key role for a kind of brief visual memory known as working memory, that helps us remember what we just saw as we look to something new. Words put ideas in working memory faster than images.""","The interaction of these two factors was not significant [F(3, 90) = 1.33, p = .27]. Figure 2A depicts mean RT for the Silent and the Label conditions as a function of distractor set size. A mixed 2 9 4 analysis of variance with condition as the between-subjects factor and set size as the withinsubjects factor yielded a significant main effect of set size [F(3, 90) = 27.30, p < 0 .001], reflecting the fact that RT increased as the number of distractors increased.",[1],Psychology,test,1.0,news,http://www.sciencedaily.com/releases/2014/04/140417090838.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29 10.1111/desc.12179,Psychology_easy_72,"Language, the study suggests, is transformative: More so than images, spoken language taps into children's cognitive system, enhancing their ability to learn and to navigate cluttered environments.","In this way, and as shown in Experiments 3 and 4, the effect of labeling does not mimic the effect of target and distractor discriminability but does mimic the effect of repeated presentations of the visual target, with labeling accomplishing at the outset what repeated visual presentations accomplish only after some number of repetitions.","Language, the study suggests, is transformative: More so than images, spoken language taps into children's cognitive system, enhancing their ability to learn and to navigate cluttered environments. As such the study, published last week in the journal Developmental Science, opens up new avenues for research into the way language might shape the course of developmental disabilities such as ADHD, difficulties with school, and other attention-related problems. ""If the name of the target object was also said, the children were much faster at finding it and less distracted by the other objects in the scene,"" said Vales, a graduate student in the Department of Psychological and Brain Sciences.","Within the limits inherent to collecting RT data from 3-year-old children, the pattern to be explained is this: Labeling affected overall search time as measured by the intercept but did not affect the additional cost of each added distractor. In this way, and as shown in Experiments 3 and 4, the effect of labeling does not mimic the effect of target and distractor discriminability but does mimic the effect of repeated presentations of the visual target, with labeling accomplishing at the outset what repeated visual presentations accomplish only after some number of repetitions. Such an effect would lead to faster overall search.",[1],Psychology,test,1.0,news,http://www.sciencedaily.com/releases/2014/04/140417090838.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29 10.1111/desc.12179,Psychology_easy_76,Vales said the use of language can change how people inspect the world around them.,"The pattern fits the hypothesis that labels influence the encoding and the maintenance of the target in working memory, an idea that has broad implications for understanding how heard words affect visual processing and performance in many cognitive tasks.","The study, she said , ""is the first clear demonstration of the impact of words on the way children navigate the visual world and is a first step toward understanding the way language influences visual attention, raising new testable hypotheses about the process."" Vales said the use of language can change how people inspect the world around them. advertisement ""We also know that language will change the way people perform in a lot of different laboratory tasks,"" she said.","In conclusion, the present results document for the first time a role for object names in directing visual attention in young children in a visual search task. The results also document visual search processes in 3-yearolds that include a dissociation of the effects of labels and target-distractor discriminability, with the labels affecting the intercept of the search function but not its slope and discriminability affecting the slope but not the intercept. The pattern fits the hypothesis that labels influence the encoding and the maintenance of the target in working memory, an idea that has broad implications for understanding how heard words affect visual processing and performance in many cognitive tasks.",[1],Psychology,test,1.0,news,http://www.sciencedaily.com/releases/2014/04/140417090838.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29 10.1111/desc.12179,Psychology_easy_77,"For instance, the difference between search times, with and without naming the target object, indicate a key role for a kind of brief visual memory known as working memory, that helps us remember what we just saw as we look to something new.",This specific result thus extends those of Experiment 1 by showing that the labeling effect occurs even when targets and distractors differ only in shape.,"Vales said their research results ""begin to tell us precisely how words help, the kinds of cognitive processes words tap into to change how children behave. For instance, the difference between search times, with and without naming the target object, indicate a key role for a kind of brief visual memory known as working memory, that helps us remember what we just saw as we look to something new. Words put ideas in working memory faster than images.""","The analysis yielded a significant main effect of Labeling [F(1, 60) = 11.10, p < .01], resulting from the overall lower RT in the Label conditions -replicating the main finding from Experiment 1 that labels decrease overall search time. This specific result thus extends those of Experiment 1 by showing that the labeling effect occurs even when targets and distractors differ only in shape. The analysis also yielded a significant main effect of Discriminability [F(1, 60) = 9.86, p < .01], as participants were overall faster when the target was placed amidst distractors that were easier to discriminate from the target, and a significant main effect of distractor set size [F(2, 120 In sum, and within the limits of these measures with young children, the results of Experiment 3 support three conclusions: First, labeling the target decreases overall search time in a task in which only shape varied, a result consistent with the hypothesis that labeling the target enhances the working memory encoding and representation of category-relevant shape.",[1],Psychology,test,1.0,news,http://www.sciencedaily.com/releases/2014/04/140417090838.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29 10.1111/desc.12179,Psychology_easy_97,"Cognitive scientists Catarina Vales and Linda Smith say that their findings open up new avenues for research into the way language shapes the course of developmental disabilities such as ADHD, difficulties with school, and other attention-related problems.",The shape bias in children's noun learning does not just concern the effect of known names on categorization but also the effect of novel names on the categorization -and name generalization of novel things.,"The study, published in Developmental Science, reveals that spoken language -- more so than images -- taps into a child's cognitive system and enhances their ability to learn, as well as to navigate cluttered environments. Cognitive scientists Catarina Vales and Linda Smith say that their findings open up new avenues for research into the way language shapes the course of developmental disabilities such as ADHD, difficulties with school, and other attention-related problems. ""If the name of the target object was also said, the children were much faster at finding it and less distracted by the other objects in the scene,"" Vales, a graduate student in the Department of Psychological and Brain Sciences, said in a recent statement.","The current findings also have implications for understanding why children are more likely to group objects by shape when they are named . The shape bias in children's noun learning does not just concern the effect of known names on categorization but also the effect of novel names on the categorization -and name generalization of novel things. By one account, this shape bias emerges as a secondorder generalization across known names and categories and is cued by the common linguistic contexts of naming things .",[1],Psychology,test,1.0,news,http://www.redorbit.com/news/health/1113124549/spoken-language-helps-direct-childrens-eyes-041814/ 10.1073/pnas.1407787111,Psychology_easy_102,"These networks, and the connections between them, mature throughout early childhood all the way to young adulthood.",These observations suggest that lagged maturation in anterior insula could contribute to several forms of inattention in ADHD.,"""But without the database of fMRI images, and the spirit of collaboration that allowed them to be compiled and shared, we would never have reached this point."" These networks, and the connections between them, mature throughout early childhood all the way to young adulthood. ""It is particularly noteworthy that the networks we found to have lagging maturation in ADHD are linked to the very behaviors that are the symptoms of ADHD,"" he says.","We found prominent maturational lag in DMN interconnections with VAN, with a concentration of lagged connections involving anterior insula, a key hub in VAN. These observations suggest that lagged maturation in anterior insula could contribute to several forms of inattention in ADHD. There was also a lag in ADHD in integration of interconnections linking DMN and FPN (Fig.",[1],Psychology,test,1.0,news,http://www.sciencedaily.com/releases/2014/09/140915153607.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29 10.1073/pnas.1407787111,Psychology_easy_103,"""The results of this study set the stage for the next phase of this research, which is to examine individual components of the networks that have the maturational lag,"" he says.","This regression modeling yielded two comprehensive maps of effect of age and effect of ADHD, respectively.","""It is particularly noteworthy that the networks we found to have lagging maturation in ADHD are linked to the very behaviors that are the symptoms of ADHD,"" he says. ""The results of this study set the stage for the next phase of this research, which is to examine individual components of the networks that have the maturational lag,"" he says. ""This study provides a coarse-grained understanding, and now we want to examine this phenomenon in a more fine-grained way that might lead us to a true biological marker, or neuromarker, for ADHD.""","Our results invite further investigation into the neurobiological mechanisms in ADHD that produce delays in development of large-scale networks. This regression modeling yielded two comprehensive maps of effect of age and effect of ADHD, respectively. Examining patterns of spatial correspondence across populations of connections in these whole-cortex connectomic maps provides a powerful way to investigate the maturational lag hypothesis.",[1],Psychology,test,1.0,news,http://www.sciencedaily.com/releases/2014/09/140915153607.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29 10.1073/pnas.1508431112,Psychology_easy_109,But the work of Poeppel and others suggests that a tonal time perception hinted at in apes and more fully formed in man could be a prerequisite for discerning a song.,We suggest further that beta activity may reflect such low-level temporal regularity in the generation of temporal predictions for upcoming notes.,"And our conscious ability to apply symbolic meaning to sounds, lyrics and song aEUR"" and to recognize when listening to music that what weaEUR(tm)re listening to is supposed to be music aEUR"" also certainly influences human musical perception. But the work of Poeppel and others suggests that a tonal time perception hinted at in apes and more fully formed in man could be a prerequisite for discerning a song. Musical appreciation might begin with our brains simply staying on beat.","We demonstrate that cortical oscillatory activity in both low (<8 Hz) and high frequencies is tightly coupled to behavioral performance in musical listening, in a bidirectional manner. We suggest further that beta activity may reflect such low-level temporal regularity in the generation of temporal predictions for upcoming notes. As such, the metric, notes per second (Materials and Methods), is meant to be associated with this more general process of event chunking-which must occur in all forms of sound stream processing-and should therefore not be confused with beat, meter, and the complex cognitive processes associated with these operations.",[1],Psychology,test,1.0,news,http://healthmedicinet.com/news/the-neuroscience-of-musical-perception-bass-guitars-and-drake/ 10.1111/desc.12179,Psychology_easy_112,"""We also know that language will change the way people perform in a lot of different laboratory tasks,"" she said.","For example, adults listening to spoken sentences look at a possible visual referent even when the visual array is irrelevant to the task (for a review see , and even look to shape-similar items when that item is clearly not the referent of the uttered word (e.g.","The way language is used can change how people perceive the world around them, Vales said. ""We also know that language will change the way people perform in a lot of different laboratory tasks,"" she said. The findings ""begin to tell us precisely how words help, the kinds of cognitive processes words tap into to change how children behave.","But clearly words can have effects on visual expectations -and where one looks in an array -without a visually presented target. For example, adults listening to spoken sentences look at a possible visual referent even when the visual array is irrelevant to the task (for a review see , and even look to shape-similar items when that item is clearly not the referent of the uttered word (e.g. By hypothesis, the underlying mechanism for these effects may be fundamentally the same as the one proposed here: Heard words yield representations (either expectations or biased encoding of seen things) in visual working memory and these active representations then drive where one looks in a scene.",[1],Psychology,test,1.0,news,http://www.redorbit.com/news/health/1113124549/spoken-language-helps-direct-childrens-eyes-041814/ 10.1073/pnas.1508431112,Psychology_easy_113,The work also reveals why your musician friends are sometimes more tolerant of really boring music.,The effect is clearly right lateralized and the topography is consistent with right auditory cortex.,"It turns out, the answer has a lot to do with timing. The work also reveals why your musician friends are sometimes more tolerant of really boring music. They found that the brain wave rhythms of nonmusicians didnaEUR(tm)t entrain to music with a tempo less than one note per second, or what would be considered slow music.","4 shows the transformed correlation (Materials and Methods) between entrainment at the dominant note rate and hit rate, at the subject level. The effect is clearly right lateralized and the topography is consistent with right auditory cortex. A second cluster in the left hemisphere did not reach significance (P = 0.14).",[1],Psychology,test,1.0,news,http://healthmedicinet.com/news/the-neuroscience-of-musical-perception-bass-guitars-and-drake/ 10.1073/pnas.1508431112,Psychology_easy_116,"Or, put another way, our brains entrain more to low frequencies.",This would appear to indicate a lower limit of 1 Hz below which entrainment is not likely without training.,"Whatever it means artistically speaking, we can train our brains to respond more precisely to music in a measurable, biologic way. Or, put another way, our brains entrain more to low frequencies. The authors speculate that this could be why the rhythm sections of so many music styles around the world rely on bass, drums and lower tones, and why discordant guitar solos and blaring saxophone leads can sound just fine when off-beat bass guitar doesnaEUR(tm)t. Poeppel cautions that this research is in its early stages, but speculates that if in fact we are more likely to entrain to lower frequencies it could help explain another critical component of musical perception: movement.","In nonmusicians, we observed no tracking below 1 Hz (Fig. This would appear to indicate a lower limit of 1 Hz below which entrainment is not likely without training. As the noise in the signal increases at 1/f, there must be a limit below which it becomes impossible to recover any significant effects.",[1],Psychology,test,1.0,news,http://healthmedicinet.com/news/the-neuroscience-of-musical-perception-bass-guitars-and-drake/ 10.1073/pnas.1508431112,Psychology_easy_119,"Moreover, musicians much more accurately detected pitch distortions--as evidenced by corresponding cortical oscillations.","2 and 15), suggest a generalization: cortical low-frequency oscillations track auditory inputs, entraining to incoming acoustic events, thereby chunking the auditory signal into elementary units for further decoding.","This difference, the researchers say, may suggest that non-musicians are unable to process the music as a continuous melody rather than as individual notes. Moreover, musicians much more accurately detected pitch distortions--as evidenced by corresponding cortical oscillations. Brain rhythms, they add, therefore appear to play a role in parsing and grouping sound streams into ""chunks"" that are then analyzed as speech or music.","Such entrainment correlates with behavior in a distortion detection task. 2 and 15), suggest a generalization: cortical low-frequency oscillations track auditory inputs, entraining to incoming acoustic events, thereby chunking the auditory signal into elementary units for further decoding. In nonmusicians, we observed no tracking below 1 Hz (Fig.",[1],Psychology,test,1.0,news,http://www.futurity.org/musicians-brains-rhythms-1034492-2/ 10.1177/1948550614537308,Psychology_easy_122,"""Among men, they are also more likely to be physically strong, and especially among college men, also more sexist, manipulative, coercive and narcissistic.""","A total of 2,413 weekly reports were completed, for an average of 10.5 of 12 weeks (SD ¼ 2.53) per participant; 94% of participants completed six or more reports.","Not unexpectedly, the types of people who constantly desire casual sex sound a bit insufferable. ""Among men, they are also more likely to be physically strong, and especially among college men, also more sexist, manipulative, coercive and narcissistic."" Crucially, the study proves that casual sex is much more textured and complex than previous research has let on.","Across all assessments, Cronbach's a were .84-.85 for depression, .85-.88 for anxiety, .91-.93 for self-esteem, and .88-.89 for life satisfaction. A total of 2,413 weekly reports were completed, for an average of 10.5 of 12 weeks (SD ¼ 2.53) per participant; 94% of participants completed six or more reports. Penetrative casual encounters were reported on 204 (8.5%) weekly reports; 90% of these weeks involved only one casual partner (maximum of three).",[1],Psychology,test,1.0,news,http://www.psmag.com/navigation/health-and-behavior/casual-sex-excellent-people-love-casual-sex-83847/ 10.1111/desc.12179,Psychology_easy_126,"As any book lover will tell you, language is transformative.","Analyses of accuracy yielded a significant main effect of Labeling [F(1, 60) = 7.35, p = .009], with accuracy higher in the Label condition, and a main effect of Discriminability [F (1, 60) = 4.67, p = .03], with accuracy higher in the High Discriminability condition.","As any book lover will tell you, language is transformative. The transformative powers, however, may reach father than an emotional reaction to novels or poetry. The study, published in Developmental Science, reveals that spoken language -- more so than images -- taps into a child's cognitive system and enhances their ability to learn, as well as to navigate cluttered environments.","Accuracy was above 80% for all conditions (see Table 1 for accuracy per condition). Analyses of accuracy yielded a significant main effect of Labeling [F(1, 60) = 7.35, p = .009], with accuracy higher in the Label condition, and a main effect of Discriminability [F (1, 60) = 4.67, p = .03], with accuracy higher in the High Discriminability condition. There was an interaction between Labeling and Discriminability on accuracy [F(1, 60) = 4.34, p = .04], as the difference in accuracy between the two labeling conditions was larger for the Low Discriminability condition.",[1],Psychology,test,1.0,news,http://www.redorbit.com/news/health/1113124549/spoken-language-helps-direct-childrens-eyes-041814/ 10.1073/pnas.1508431112,Psychology_easy_137,"Whatever it means artistically speaking, we can train our brains to respond more precisely to music in a measurable, biologic way.","What we consider intriguing is that this sensorimotor network, with a primary function in rhythmic processing, affects performance on a nonrhythmic task.","aEURoeMaybe youaEUR(tm)re still a really bad piano player despite your brain rhythms locking on, but most of our musicians were conservatory trained so presumably theyaEUR(tm)re pretty good,aEUR he jokes. Whatever it means artistically speaking, we can train our brains to respond more precisely to music in a measurable, biologic way. Or, put another way, our brains entrain more to low frequencies.","Plausibly, then, music-with its inherent rhythmicity-also drives this system. What we consider intriguing is that this sensorimotor network, with a primary function in rhythmic processing, affects performance on a nonrhythmic task. We suggest two possible explanations: first, beta oscillations predict only timing, as previously suggested , and, in making accurate predictions, facilitate other mechanisms to process pitch content; or second, more provocatively, beta oscillations contain specific predictions not only of when but also of what.",[1],Psychology,test,1.0,news,http://healthmedicinet.com/news/the-neuroscience-of-musical-perception-bass-guitars-and-drake/ 10.1073/pnas.1508431112,Psychology_easy_139,The jam went surprisingly well.,New data will be required to dissociate between these interpretations.,"The jam went surprisingly well. And itaEUR(tm)s not just apes that respond to song. How brain waves entrain to music This image, taken from an MEG reading, shows a musicianaEUR(tm)s brain more strongly entraining to BeethovenaEUR(tm)s unhurried Sonata No.","This interpretation, although not definitive, demonstrates the temporal structure that an oscillatory mechanism might impose onto the processing of an auditory signal. New data will be required to dissociate between these interpretations. We show that cortical entrainment is enhanced with years of musical training.",[1],Psychology,test,1.0,news,http://healthmedicinet.com/news/the-neuroscience-of-musical-perception-bass-guitars-and-drake/ 10.1073/pnas.1508431112,Psychology_easy_148,"aEURoeListening to music doesnaEUR(tm)t just activate the auditory regions of the brain,aEUR Poeppel explains.","These findings, taken together, show that beta oscillations play an important role in musical processing and are increased with musical training.","The authors speculate that this could be why the rhythm sections of so many music styles around the world rely on bass, drums and lower tones, and why discordant guitar solos and blaring saxophone leads can sound just fine when off-beat bass guitar doesnaEUR(tm)t. Poeppel cautions that this research is in its early stages, but speculates that if in fact we are more likely to entrain to lower frequencies it could help explain another critical component of musical perception: movement. aEURoeListening to music doesnaEUR(tm)t just activate the auditory regions of the brain,aEUR Poeppel explains. aEURoeRhythmic input also automatically activates your motor cortex too.","6F ). These findings, taken together, show that beta oscillations play an important role in musical processing and are increased with musical training. To our knowledge, these data represent the first demonstration of cortical phase entrainment of delta-theta oscillations to natural music.",[1],Psychology,test,1.0,news,http://healthmedicinet.com/news/the-neuroscience-of-musical-perception-bass-guitars-and-drake/ 10.1111/desc.12179,Psychology_easy_149,"Words have a way of calling up what you know that filters the environment for you.""","Analyses of accuracy revealed no significant main effects of condition [F(1, 38) = 0.10, p = .75] or set size [F(2, 76) = 0.01, p = .99].","""Words call up an idea that is more robust than an image and to which we more rapidly respond. Words have a way of calling up what you know that filters the environment for you."" The study, she said , ""is the first clear demonstration of the impact of words on the way children navigate the visual world and is a first step toward understanding the way language influences visual attention, raising new testable hypotheses about the process.""","Mean accuracy was above 90% for both conditions (see Table 1 ). Analyses of accuracy revealed no significant main effects of condition [F(1, 38) = 0.10, p = .75] or set size [F(2, 76) = 0.01, p = .99]. The two factors did not interact [F(2, 76) = 2.72, p = .07].",[1],Psychology,test,1.0,news,http://www.sciencedaily.com/releases/2014/04/140417090838.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29 10.1073/pnas.1508431112,Psychology_easy_160,However the musiciansaEUR(tm) brain waves buzzed in synchrony to music as slow as 0.7 notes per second.,"Another alternative is that the added complexity of music engages a range of other, more complex brain functions, making it difficult to detect this specific relationship using the tools available in this study.","They found that the brain wave rhythms of nonmusicians didnaEUR(tm)t entrain to music with a tempo less than one note per second, or what would be considered slow music. However the musiciansaEUR(tm) brain waves buzzed in synchrony to music as slow as 0.7 notes per second. aEURoeIt looks like musicians can take longer, more drawn out musical phrases and group them into a pattern of some kind,aEUR says Poeppel, aEURoethe response to what some people perceive as just a series of beeps and blips turns on much more sharply in musicians.aEUR Dr. Devin McAuley, a professor of cognitive science at Michigan State University who wasnaEUR(tm)t involved with the study says, aEURoeThese are exciting findings that fit into a broader body of work.","Had the task been to detect a rhythmic distortion or to tap to the beat, one might expect more nesting between delta and beta, as has been recently shown using isochronous tones . Another alternative is that the added complexity of music engages a range of other, more complex brain functions, making it difficult to detect this specific relationship using the tools available in this study. Conclusions.",[1],Psychology,test,1.0,news,http://healthmedicinet.com/news/the-neuroscience-of-musical-perception-bass-guitars-and-drake/ 10.1177/1948550614537308,Psychology_easy_161,"Even though these study's findings contradicted other study's findings, they explain that their study found positive effects of having casual sex for people who wanted to engage in it in the first place.","Our study has several strengths, including a university-wide sample and converging evidence from longitudinal and weekly diary methodologies.","They also reported having less stress and better emotional health. Even though these study's findings contradicted other study's findings, they explain that their study found positive effects of having casual sex for people who wanted to engage in it in the first place. The researchers added that if people do not have casual sex for the right reasons, the activity could result in negative consequences.","High sociosexuality, on the other hand, may be useful for successfully navigating the greater complexities of the more intimate and involved longer casual relationships (Vrangalova, in press; . Our study has several strengths, including a university-wide sample and converging evidence from longitudinal and weekly diary methodologies. However, the initial response rate was low (13%), raising the possibility of self-selection bias, and base rates of casual sex were low leading to limited statistical power.",[1],Psychology,test,1.0,news,http://www.counselheal.com/articles/10249/20140626/casual-sex-can-be-good-study-reports.htm 10.1177/0013916516628178,Psychology_easy_169,Having a squeaky-clean countertop might also inspire you to finally cook more meals at home.,"Results suggest that an individual's mind-set can moderate the impact of a chaotic environment on food intake, particularly for sweet foods.","Small appliances like your toaster or blender should be tucked away in a cupboard. Having a squeaky-clean countertop might also inspire you to finally cook more meals at home. Well, for starters, you won't feel stressed just from stepping into your kitchen.","There were also no significant main effects or interactions involving either cracker or carrot consumption. Results suggest that an individual's mind-set can moderate the impact of a chaotic environment on food intake, particularly for sweet foods. Although a chaotic environment may be a risk factor for making unhealthy choices, one's mind-set in that environment can either trigger or buffer against that risk factor.",[1],Psychology,test,1.0,news,http://ct.moreover.com/?a=38805821479&p=1pl&v=1&x=ys7fkwVi17p1COyx6LHdrw 10.1111/desc.12179,Psychology_easy_177,The words you know are a driving force behind attention.,The principal effect of labels may be that they shortcut visual learning from repeated presentations.,"""If you don't know where to look, chances are you don't learn anything. The words you know are a driving force behind attention. ""Our results suggest that language has huge effects, not just on talking, but on attention -- which can determine how children learn, how much they learn and how well they learn,"" Vales said.","If repetitions of the visual target lead, more slowly, to robust representation of the target, then search times in the Silent condition should improve from first to second half. The principal effect of labels may be that they shortcut visual learning from repeated presentations. Ten additional children were recruited but not included in the final sample due to refusal to participate in the study (N = 5), selecting a non-target object on most test trials and thereby not meeting the criterion of at least two correct responses per distractor set size (N = 3), not finishing the familiarization phase (N = 1) and experimenter error (N = 1).",[1],Psychology,test,1.0,news,http://www.sciencedaily.com/releases/2014/04/140417090838.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29 10.1111/desc.12179,Psychology_easy_181,"This turns it around because it suggests that language may also make working memory more effective.""","In conclusion, the present results document for the first time a role for object names in directing visual attention in young children in a visual search task.","""This study changes the causal arrow a little bit. This turns it around because it suggests that language may also make working memory more effective."" ""If you don't know where to look, chances are you don't learn anything.","The present results -by implicating a role for words in the quality of visual working memory representations -may provide new paths for understanding the development and individual differences in working memory processes. In conclusion, the present results document for the first time a role for object names in directing visual attention in young children in a visual search task. The results also document visual search processes in 3-yearolds that include a dissociation of the effects of labels and target-distractor discriminability, with the labels affecting the intercept of the search function but not its slope and discriminability affecting the slope but not the intercept.",[1],Psychology,test,1.0,news,http://www.sciencedaily.com/releases/2014/04/140417090838.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29 10.1177/0013916516628178,Psychology_easy_188,"It seems to lead people to think, 'Everything else is out of control, so why shouldn't I be?'""","In the context of the chaotic environment combined with an out-of-control mindset, increased cookie consumption might have been the result of depleted selfregulatory strength from managing one's emotions under such conditions.","In total they ate 65 more calories more in 10 minutes time. It seems to lead people to think, 'Everything else is out of control, so why shouldn't I be?'"" ""I suspect the same would hold with males,"" he adds.","Because sweet foods are generally seen as being ""forbidden"" foods , some degree of effort was perhaps needed to resist eating too many cookies. In the context of the chaotic environment combined with an out-of-control mindset, increased cookie consumption might have been the result of depleted selfregulatory strength from managing one's emotions under such conditions. Of course, future research is needed to directly test this hypothesis.",[1],Psychology,test,1.0,news,http://www.science20.com/news_articles/clean_kitchens_cut_calories-164873 10.1073/pnas.1508431112,Psychology_easy_198,The findings also suggest musical training can enhance the functional role of brain rhythms.,"Recordings from nonmusicians demonstrate cortical entrainment that tracks musical stimuli over a typical range of tempi, but not at tempi below 1 note per second.","The study, which appears in the Proceedings of the National Academy of Sciences, points to a newfound role the brain's cortical oscillations play in the detection of musical sequences. The findings also suggest musical training can enhance the functional role of brain rhythms. ""Specifically, our findings show that the presence of these rhythms enhances our perception of music and of pitch changes.""","We demonstrate that cortical oscillatory activity in both low (<8 Hz) and high (15-30 Hz) frequencies is tightly coupled to behavioral performance in musical listening, in a bidirectional manner. Recordings from nonmusicians demonstrate cortical entrainment that tracks musical stimuli over a typical range of tempi, but not at tempi below 1 note per second. Importantly, the observed entrainment correlates with performance on a concurrent pitch-related behavioral task.",[1],Psychology,test,1.0,news,http://www.futurity.org/musicians-brains-rhythms-1034492-2/ 10.1073/pnas.1508431112,Psychology_easy_201,The work also reveals why your musician friends are sometimes more tolerant of really boring music.,This suggests a communication-throughcoherence mechanism in which relevant brain regions gain access to the stimulus by entraining to the parsing mechanism.,"It turns out, the answer has a lot to do with timing. The work also reveals why your musician friends are sometimes more tolerant of really boring music. They found that the brain wave rhythms of nonmusicians didnaEUR(tm)t entrain to music with a tempo less than one note per second, or what would be considered slow music.","found that cortical entrainment was selectively increased in posterior middle temporal gyrus, associated with lexical access , when sentences were intelligible. This suggests a communication-throughcoherence mechanism in which relevant brain regions gain access to the stimulus by entraining to the parsing mechanism. A similar effect could be occurring in musicians where training manifests structural and functional changes, presumably, to optimize processing and production of musical stimuli.",[1],Psychology,test,1.0,news,http://healthmedicinet.com/news/the-neuroscience-of-musical-perception-bass-guitars-and-drake/ 10.1111/desc.12179,Psychology_easy_204,"""If you don't know where to look, chances are you don't learn anything.","The two factors did not interact [F(2, 76) = 2.72, p = .07].","This turns it around because it suggests that language may also make working memory more effective."" ""If you don't know where to look, chances are you don't learn anything. The words you know are a driving force behind attention.","Analyses of accuracy revealed no significant main effects of condition [F(1, 38) = 0.10, p = .75] or set size [F(2, 76) = 0.01, p = .99]. The two factors did not interact [F(2, 76) = 2.72, p = .07]. In the first block of 18 trials, the presentation of the target name seems to have speeded up search, similar to the previous experiments.",[1],Psychology,test,1.0,news,http://www.sciencedaily.com/releases/2014/04/140417090838.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29 10.1073/pnas.1508431112,Psychology_easy_215,"Brain rhythms, they add, therefore appear to play a role in parsing and grouping sound streams into ""chunks"" that are then analyzed as speech or music.","In addition, higher-frequency activity merits scrutiny.","This difference, the researchers say, may suggest that non-musicians are unable to process the music as a continuous melody rather than as individual notes. Moreover, musicians much more accurately detected pitch distortions--as evidenced by corresponding cortical oscillations. Brain rhythms, they add, therefore appear to play a role in parsing and grouping sound streams into ""chunks"" that are then analyzed as speech or music.","Overall, the data suggest that, although cortical entrainment is necessary to support intelligibility of continuous speech-perhaps by parsing the input stream into chunks for subsequent decodingthe reverse does not hold: ""intelligibility"" is not required to drive entrainment. In addition, higher-frequency activity merits scrutiny. Furthermore, prestimulus beta plays a role in generating accurate temporal predictions even in pure listening tasks .",[1],Psychology,test,1.0,news,http://www.futurity.org/musicians-brains-rhythms-1034492-2/ 10.1177/0013916516628178,Psychology_easy_223,"""I suspect the same would hold with males,"" he adds.",It is possible that eating behavior that takes place in the midst of a chaotic environment differs from eating behavior that takes place once the individual is removed from that chaotic environment.,"It seems to lead people to think, 'Everything else is out of control, so why shouldn't I be?'"" ""I suspect the same would hold with males,"" he adds. The latter group entered the cluttered room feeling in control and ate about 100 fewer calories than those who felt out of control before entering.","Furthermore, in the present study, the eating took place after the ""chaos"" had ended, which might not be the case in many real-world situations. It is possible that eating behavior that takes place in the midst of a chaotic environment differs from eating behavior that takes place once the individual is removed from that chaotic environment. An important avenue for future research, therefore, would be to examine the time course of the chaotic-environment/food-intake association.",[1],Psychology,test,1.0,news,http://www.science20.com/news_articles/clean_kitchens_cut_calories-164873 10.1002/hbm.23447,Psychology_easy_233,Pinkett Smith says she healed on her own.,"Non-BOLD components are removed by projection, de-noising data for motion, physiological and scanner artifacts in a robust manner based on physical principles.","These addictions destroyed lives."" Pinkett Smith says she healed on her own. That's the thing about me: I can go cold turkey.","BOLD signal percent signal change is linearly dependent on TE, a characteristic of the T2* decay. Non-BOLD components are removed by projection, de-noising data for motion, physiological and scanner artifacts in a robust manner based on physical principles. Significant principal components of the signals from WM and CSF were removed.",[1],Psychology,test,1.0,news,http://ct.moreover.com/?a=34509238652&p=1pl&v=1&x=rNOM6nfRJCfJ0YdUgZsUtA 10.1111/desc.12179,Psychology_easy_239,"The study, published in Developmental Science, reveals that spoken language -- more so than images -- taps into a child's cognitive system and enhances their ability to learn, as well as to navigate cluttered environments.","There was also a reliable main effect of Block [F(1, 38) = 4.0, p = .05], as RT was overall lower on the second block.","The transformative powers, however, may reach father than an emotional reaction to novels or poetry. The study, published in Developmental Science, reveals that spoken language -- more so than images -- taps into a child's cognitive system and enhances their ability to learn, as well as to navigate cluttered environments. Cognitive scientists Catarina Vales and Linda Smith say that their findings open up new avenues for research into the way language shapes the course of developmental disabilities such as ADHD, difficulties with school, and other attention-related problems.","There was a reliable main effect of distractor set size [F(2, 76) = 39.9, p < .001], reflecting the increase in RT with increasing number of distractors. There was also a reliable main effect of Block [F(1, 38) = 4.0, p = .05], as RT was overall lower on the second block. Although there was no reliable main effect of Labeling [F(1, 38) = 0.9, p = .34], there was a significant interaction between Labeling and Block [F(1, 38) = 4.4, p < .05], suggesting that the difference between the two labeling conditions was modulated by the repetition of the visual information.",[1],Psychology,test,1.0,news,http://www.redorbit.com/news/health/1113124549/spoken-language-helps-direct-childrens-eyes-041814/ 10.1073/pnas.1508431112,Psychology_easy_240,"This difference, the researchers say, may suggest that non-musicians are unable to process the music as a continuous melody rather than as individual notes.","What we consider intriguing is that this sensorimotor network, with a primary function in rhythmic processing, affects performance on a nonrhythmic task.","Only musicians, however, showed oscillations that synchronized with unusually slow clips. This difference, the researchers say, may suggest that non-musicians are unable to process the music as a continuous melody rather than as individual notes. Moreover, musicians much more accurately detected pitch distortions--as evidenced by corresponding cortical oscillations.","Plausibly, then, music-with its inherent rhythmicity-also drives this system. What we consider intriguing is that this sensorimotor network, with a primary function in rhythmic processing, affects performance on a nonrhythmic task. We suggest two possible explanations: first, beta oscillations predict only timing, as previously suggested , and, in making accurate predictions, facilitate other mechanisms to process pitch content; or second, more provocatively, beta oscillations contain specific predictions not only of when but also of what.",[1],Psychology,test,1.0,news,http://www.futurity.org/musicians-brains-rhythms-1034492-2/ 10.1073/pnas.1508431112,Psychology_easy_241,"This difference, the researchers say, may suggest that non-musicians are unable to process the music as a continuous melody rather than as individual notes.",The entrainment effects observed here are presumably the result of one (or many) of these changes.,"Only musicians, however, showed oscillations that synchronized with unusually slow clips. This difference, the researchers say, may suggest that non-musicians are unable to process the music as a continuous melody rather than as individual notes. Moreover, musicians much more accurately detected pitch distortions--as evidenced by corresponding cortical oscillations.","24-31, 53, and 54) shows that musical training elicits a range of changes to brain structure and function. The entrainment effects observed here are presumably the result of one (or many) of these changes. These questions cannot be answered within the scope of this study; however, we present several hypotheses to inspire future research.",[1],Psychology,test,1.0,news,http://www.futurity.org/musicians-brains-rhythms-1034492-2/ 10.1111/desc.12179,Psychology_easy_247,"""We also know that language will change the way people perform in a lot of different laboratory tasks,"" she said.",There were no other significant interactions.,"The way language is used can change how people perceive the world around them, Vales said. ""We also know that language will change the way people perform in a lot of different laboratory tasks,"" she said. The findings ""begin to tell us precisely how words help, the kinds of cognitive processes words tap into to change how children behave.","Although there was no reliable main effect of Labeling [F(1, 38) = 0.9, p = .34], there was a significant interaction between Labeling and Block [F(1, 38) = 4.4, p < .05], suggesting that the difference between the two labeling conditions was modulated by the repetition of the visual information. There were no other significant interactions. An analysis of variance with the intercept as the dependent variable failed to find any significant main effects or interactions as did the corresponding analysis of the slopes.",[1],Psychology,test,1.0,news,http://www.redorbit.com/news/health/1113124549/spoken-language-helps-direct-childrens-eyes-041814/ 10.1111/desc.12179,Psychology_easy_251,Vales said the use of language can change how people inspect the world around them.,"In both cases, the objects were composed of multiple line elements and thus might be considered as instances of a conjunctive search task, as finding the target depends on attending to multiple line elements in the right configuration for the category-relevant shape (e.g.","The study, she said , ""is the first clear demonstration of the impact of words on the way children navigate the visual world and is a first step toward understanding the way language influences visual attention, raising new testable hypotheses about the process."" Vales said the use of language can change how people inspect the world around them. advertisement ""We also know that language will change the way people perform in a lot of different laboratory tasks,"" she said.","But if category name cues attention to shape because of its association with category-relevant shape properties, hearing the name of the target object should also benefit attention to category-specific shape (and not just to shape over color). In both cases, the objects were composed of multiple line elements and thus might be considered as instances of a conjunctive search task, as finding the target depends on attending to multiple line elements in the right configuration for the category-relevant shape (e.g. While the Low Discriminability condition clearly requires attending to the configural properties of multiple elements to discriminate between the distractors and the target, the High Discriminability might not as the targets and distractors could be discriminated on a single shape feature (e.g.",[1],Psychology,test,1.0,news,http://www.sciencedaily.com/releases/2014/04/140417090838.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29 10.1073/pnas.1407787111,Psychology_easy_252,"""It is particularly noteworthy that the networks we found to have lagging maturation in ADHD are linked to the very behaviors that are the symptoms of ADHD,"" he says.",These findings across imaging modalities underscore a broader point: the functional abnormalities we observed within and between DMN and TPNs are likely to be part of a larger picture of developmental delays of structural characteristics such as cortical thickness and white matter tracts (see ref.,"These networks, and the connections between them, mature throughout early childhood all the way to young adulthood. ""It is particularly noteworthy that the networks we found to have lagging maturation in ADHD are linked to the very behaviors that are the symptoms of ADHD,"" he says. ""The results of this study set the stage for the next phase of this research, which is to examine individual components of the networks that have the maturational lag,"" he says.","found diffuse maturational delay in cortical thickness in ADHD, with peak delays in medial prefrontal regions in DMN. These findings across imaging modalities underscore a broader point: the functional abnormalities we observed within and between DMN and TPNs are likely to be part of a larger picture of developmental delays of structural characteristics such as cortical thickness and white matter tracts (see ref. Joint, multimodal investigation of this ensemble of structural and functional characteristics in ADHD could provide insights into the mechanisms that produce and sustain the disorder.",[1],Psychology,test,1.0,news,http://www.newswise.com/articles/slow-to-mature-quick-to-distract-adhd-brain-study-finds-slower-development-of-key-connections 10.1111/desc.12179,Psychology_easy_262,"The transformative powers, however, may reach father than an emotional reaction to novels or poetry.",Such an effect would lead to faster overall search.,"As any book lover will tell you, language is transformative. The transformative powers, however, may reach father than an emotional reaction to novels or poetry. The study, published in Developmental Science, reveals that spoken language -- more so than images -- taps into a child's cognitive system and enhances their ability to learn, as well as to navigate cluttered environments.","In this way, and as shown in Experiments 3 and 4, the effect of labeling does not mimic the effect of target and distractor discriminability but does mimic the effect of repeated presentations of the visual target, with labeling accomplishing at the outset what repeated visual presentations accomplish only after some number of repetitions. Such an effect would lead to faster overall search. These are illustrated in Figure 6 .",[1],Psychology,test,1.0,news,http://www.redorbit.com/news/health/1113124549/spoken-language-helps-direct-childrens-eyes-041814/ 10.1111/jcpp.12015,Psychology_easy_264,"That, the 42-year-old Minneapolis mom says, is because she and her husband began explaining things early.","The European study found no differences in emotional or behavioral problems between children conceived by either sperm donation or egg donation , and comparison groups of IVF, naturally conceived and early-adopted children.","For Jill Wolfe's kids, surrogacy seems completely natural. That, the 42-year-old Minneapolis mom says, is because she and her husband began explaining things early. As proof of how normal this all seems to Eliana, now 6, Wolfe recalls the day her daughter told a friend about the surrogacy.","In the European Study of Assisted Reproduction Families, not one set of parents from a representative sample of more than 100 donor insemination families had disclosed the donor conception to their child by early school age , and less than 10% had done so by early adolescence . The European study found no differences in emotional or behavioral problems between children conceived by either sperm donation or egg donation , and comparison groups of IVF, naturally conceived and early-adopted children. However, as reported above, almost all these children were unaware of their donor conception.",[1],Psychology,test,1.0,news,http://www.today.com/health/new-study-tracks-emotional-health-surrogate-kids-6C10366818 10.1177/1948550614537308,Psychology_easy_277,"""And we need more research that will examine these various factors, and move the discourse away from the black-and-white picture often painted and toward these more useful nuances.""","Of these, 71% were also included in the 9-month sample.","Crucially, the study proves that casual sex is much more textured and complex than previous research has let on. ""This study and a previous study of mine are some of the first studies to show that hooking up is not always bad or good for everyone, that it depends on various personal, interpersonal and situational factors,"" Vrangalova says. ""And we need more research that will examine these various factors, and move the discourse away from the black-and-white picture often painted and toward these more useful nuances.""","Ten participants were excluded for reporting they were in a romantic relationship across the entire study, bringing the final weekly sample to 230 (65% female; 36% non-White; and 48% freshmen). Of these, 71% were also included in the 9-month sample. In both the weekly and 9-month samples, men (M ¼ 4.16, standard deviation [SD] ¼ 1.51, and M ¼ 3.93; SD ¼ 1.45, respectively) reported higher sociosexuality than women (M ¼ 3.54, SD ¼ 1.51, and M ¼ 3.21; SD ¼ 1.50), t(228) ¼ 2.98, p ¼ .003, and t(369) ¼ 4.47, p < .001; therefore, scores were centered within sex prior to analyses.",[1],Psychology,test,1.0,news,http://www.psmag.com/navigation/health-and-behavior/casual-sex-excellent-people-love-casual-sex-83847/ 10.1177/1948550614537308,Psychology_easy_281,"""I found that whether or not students hooked up during the course of the year was not related to their well-being at the end of the year,"" Vrangalova previously wrote according to HuffPost.","Finally, additional analyses of the 9-month follow-up indicated the moderating effect of sociosexuality may be limited to longer casual partners.","The reasons could be autonomous or non-autonomous. ""I found that whether or not students hooked up during the course of the year was not related to their well-being at the end of the year,"" Vrangalova previously wrote according to HuffPost. ""However, whether they did it for nonautonomous motives was.""","Future studies need to examine this. Finally, additional analyses of the 9-month follow-up indicated the moderating effect of sociosexuality may be limited to longer casual partners. This could be due to low power (as one-time encounters were rarer) or to substantive differences between the two types of casual sex.",[1],Psychology,test,1.0,news,http://www.counselheal.com/articles/10249/20140626/casual-sex-can-be-good-study-reports.htm 10.1073/pnas.1508431112,Psychology_easy_284,"ItaEUR(tm)s also been shown that children with musical training have a slower preferred tempo than kids who havenaEUR(tm)t had training.aEUR The findings might help explain why aEUR"" in my completely unscientific sampling of friends and acquaintances aEUR"" musicians tend to be more tolerant of slow, ambient, droning music (my pal Kevin thrives at a dreamy 0.6 notes per second).",This correlation between beta power (mean of values within dashed box in Fig.,"aEURoeIt looks like musicians can take longer, more drawn out musical phrases and group them into a pattern of some kind,aEUR says Poeppel, aEURoethe response to what some people perceive as just a series of beeps and blips turns on much more sharply in musicians.aEUR Dr. Devin McAuley, a professor of cognitive science at Michigan State University who wasnaEUR(tm)t involved with the study says, aEURoeThese are exciting findings that fit into a broader body of work. ItaEUR(tm)s also been shown that children with musical training have a slower preferred tempo than kids who havenaEUR(tm)t had training.aEUR The findings might help explain why aEUR"" in my completely unscientific sampling of friends and acquaintances aEUR"" musicians tend to be more tolerant of slow, ambient, droning music (my pal Kevin thrives at a dreamy 0.6 notes per second). They might also explain why musicians appear to be more attuned to environmental sounds, like picking out a single voice in the din of a crowded room.","No correlation is found with the alpha band (as was found in the nonmusicians accuracy contrast; Fig. This correlation between beta power (mean of values within dashed box in Fig. 6A ) is evident when examining the combined musician and nonmusician group (R 2 = 0.505, P < 0.0001; Fig.",[1],Psychology,test,1.0,news,http://healthmedicinet.com/news/the-neuroscience-of-musical-perception-bass-guitars-and-drake/ 10.1073/pnas.1508431112,Psychology_easy_293,"""What this shows is we can be trained, in effect, to make more efficient use of our auditory-detection systems,"" observes study coauthor David Poeppel, a professor in psychology department and Center for Neural Science and director of the Max Planck Institute for Empirical Aesthetics in Frankfurt.","Another alternative is that the added complexity of music engages a range of other, more complex brain functions, making it difficult to detect this specific relationship using the tools available in this study.","Not surprisingly, the study found that musicians have more potent oscillatory mechanisms than do non-musicians--but this discovery's importance goes beyond the value of musical instruction. ""What this shows is we can be trained, in effect, to make more efficient use of our auditory-detection systems,"" observes study coauthor David Poeppel, a professor in psychology department and Center for Neural Science and director of the Max Planck Institute for Empirical Aesthetics in Frankfurt. ""Musicians, through their experience, are simply better at this type of processing.""","Had the task been to detect a rhythmic distortion or to tap to the beat, one might expect more nesting between delta and beta, as has been recently shown using isochronous tones . Another alternative is that the added complexity of music engages a range of other, more complex brain functions, making it difficult to detect this specific relationship using the tools available in this study. Conclusions.",[1],Psychology,test,1.0,news,http://www.futurity.org/musicians-brains-rhythms-1034492-2/ 10.1073/pnas.1508431112,Psychology_easy_312,"They might also explain why musicians appear to be more attuned to environmental sounds, like picking out a single voice in the din of a crowded room.","As musical training requires synchronous processing of somatosensory, motor, and visual areas, these areas will likely provide modulatory rhythmic input into auditory cortex, further enhancing entrainment to the musical stimulus.","ItaEUR(tm)s also been shown that children with musical training have a slower preferred tempo than kids who havenaEUR(tm)t had training.aEUR The findings might help explain why aEUR"" in my completely unscientific sampling of friends and acquaintances aEUR"" musicians tend to be more tolerant of slow, ambient, droning music (my pal Kevin thrives at a dreamy 0.6 notes per second). They might also explain why musicians appear to be more attuned to environmental sounds, like picking out a single voice in the din of a crowded room. Poeppel is quick to acknowledge that his work by no means proves that entrainment equates with being a good musician.","ref. As musical training requires synchronous processing of somatosensory, motor, and visual areas, these areas will likely provide modulatory rhythmic input into auditory cortex, further enhancing entrainment to the musical stimulus. Last, the training effect we show could be due to recruitment of more brain regions for processing music.",[1],Psychology,test,1.0,news,http://healthmedicinet.com/news/the-neuroscience-of-musical-perception-bass-guitars-and-drake/ 10.1111/jcpp.12015,Psychology_easy_314,"For Jill Wolfe's kids, surrogacy seems completely natural.",Conclusions: The absence of a gestational connection to the mother may be more problematic for children than the absence of a genetic link.,"While all the children seemed to be doing well by age 10, Golombok says, the concern is, trouble could crop up later as kids hit their adolescence and are trying to find their identities and place in the world, experts say. For Jill Wolfe's kids, surrogacy seems completely natural. That, the 42-year-old Minneapolis mom says, is because she and her husband began explaining things early.","However, maternal distress had a more negative impact on children who were aware of their origins. Conclusions: The absence of a gestational connection to the mother may be more problematic for children than the absence of a genetic link. When the mother's egg and father's sperm are used in IVF and the mother undergoes the pregnancy, the parents have both a genetic and gestational link to the child in the same way as parents of naturally conceived children.",[1],Psychology,test,1.0,news,http://www.today.com/health/new-study-tracks-emotional-health-surrogate-kids-6C10366818 10.1073/pnas.1508431112,Psychology_easy_319,"""What this shows is we can be trained, in effect, to make more efficient use of our auditory-detection systems,"" observes study coauthor David Poeppel, a professor in psychology department and Center for Neural Science and director of the Max Planck Institute for Empirical Aesthetics in Frankfurt.","As expected, we found ( Importantly, we also found a main effect of musical expertise [F (1,66) = 9.12, P < 0.005].","Not surprisingly, the study found that musicians have more potent oscillatory mechanisms than do non-musicians--but this discovery's importance goes beyond the value of musical instruction. ""What this shows is we can be trained, in effect, to make more efficient use of our auditory-detection systems,"" observes study coauthor David Poeppel, a professor in psychology department and Center for Neural Science and director of the Max Planck Institute for Empirical Aesthetics in Frankfurt. ""Musicians, through their experience, are simply better at this type of processing.""","Musical Training Enhances Entrainment. As expected, we found ( Importantly, we also found a main effect of musical expertise [F (1,66) = 9.12, P < 0.005]. Post hoc planned comparisons showed significant differences of musical expertise for 1.5 nps (P < 0.05) and at 0.7 nps (P < 0.05).",[1],Psychology,test,1.0,news,http://www.futurity.org/musicians-brains-rhythms-1034492-2/ 10.1111/desc.12179,Psychology_easy_323,"Cognitive scientists Catarina Vales and Linda Smith say that their findings open up new avenues for research into the way language shapes the course of developmental disabilities such as ADHD, difficulties with school, and other attention-related problems.",Adults are faster when the target is labeled prior to search .,"The study, published in Developmental Science, reveals that spoken language -- more so than images -- taps into a child's cognitive system and enhances their ability to learn, as well as to navigate cluttered environments. Cognitive scientists Catarina Vales and Linda Smith say that their findings open up new avenues for research into the way language shapes the course of developmental disabilities such as ADHD, difficulties with school, and other attention-related problems. ""If the name of the target object was also said, the children were much faster at finding it and less distracted by the other objects in the scene,"" Vales, a graduate student in the Department of Psychological and Brain Sciences, said in a recent statement.","The overall pattern fits contemporary theories of how the contents of visual working memory interact with visual search and attention, and shows that even in very young children heard words affect the processing of visual information. Adults are faster when the target is labeled prior to search . Adults are also faster at finding the target when they are holding information in memory that matches the target or when they have been presented with a visual preview of the specific target .",[1],Psychology,test,1.0,news,http://www.redorbit.com/news/health/1113124549/spoken-language-helps-direct-childrens-eyes-041814/ 10.1177/0013916516628178,Psychology_easy_324,"When stressed out females were asked to wait for another person in a messy kitchen -- with newspapers on the table, dishes in the sink, and the phone ringing - they ate twice as many cookies compared to women in the same kitchen when it was organized and quiet.","This study has two key findings that are relevant to health care providers, clinical workers, and dieters.","Cluttered and chaotic environments can cause stress, which can lead us to grab more of the indulgent snacks-- twice as many cookies according to this new study! When stressed out females were asked to wait for another person in a messy kitchen -- with newspapers on the table, dishes in the sink, and the phone ringing - they ate twice as many cookies compared to women in the same kitchen when it was organized and quiet. In total they ate 65 more calories more in 10 minutes time.","Examining such characteristics could help to determine which individuals are mostly likely to be vulnerable to the negative impact that stressful situations can have on food intake, and which individuals are mostly likely to benefit from learning to modify their mindset in such situations. This study has two key findings that are relevant to health care providers, clinical workers, and dieters. First, it underscores that less cluttered, less distracting, and less chaotic environments may lead people to snack less than they would in a more cluttered and chaotic workplace.",[1],Psychology,test,1.0,news,http://www.science20.com/news_articles/clean_kitchens_cut_calories-164873 10.1073/pnas.1508431112,Psychology_easy_342,"It turns out, the answer has a lot to do with timing.",Our findings provide evidence that the role of beta in temporal predictions scales to the complex hierarchical rhythms in natural music and enhances processing of musical content.,"How brain waves entrain to music This image, taken from an MEG reading, shows a musicianaEUR(tm)s brain more strongly entraining to BeethovenaEUR(tm)s unhurried Sonata No. It turns out, the answer has a lot to do with timing. The work also reveals why your musician friends are sometimes more tolerant of really boring music.","This suggests a bidirectional relationship between behavior and cortical entrainment, a phenomenon that has not previously been reported. Our findings provide evidence that the role of beta in temporal predictions scales to the complex hierarchical rhythms in natural music and enhances processing of musical content. This study builds on important findings on brainstem plasticity and represents a compelling demonstration that cortical neural entrainment is tightly coupled to both musical training and task performance, further supporting a role for cortical oscillatory activity in music perception and cognition.",[1],Psychology,test,1.0,news,http://healthmedicinet.com/news/the-neuroscience-of-musical-perception-bass-guitars-and-drake/ 10.1073/pnas.1508431112,Psychology_easy_343,And itaEUR(tm)s not just apes that respond to song.,"6A ) is evident when examining the combined musician and nonmusician group (R 2 = 0.505, P < 0.0001; Fig.","The jam went surprisingly well. And itaEUR(tm)s not just apes that respond to song. How brain waves entrain to music This image, taken from an MEG reading, shows a musicianaEUR(tm)s brain more strongly entraining to BeethovenaEUR(tm)s unhurried Sonata No.","This correlation between beta power (mean of values within dashed box in Fig. 6A ) is evident when examining the combined musician and nonmusician group (R 2 = 0.505, P < 0.0001; Fig. We observed a similar beta-power increase that persisted beyond the target only in the left auditory channels (Fig.",[1],Psychology,test,1.0,news,http://healthmedicinet.com/news/the-neuroscience-of-musical-perception-bass-guitars-and-drake/ 10.1073/pnas.1407787111,Psychology_easy_365,The new findings mesh well with what other researchers have found by examining the physical structure of the brains of people with and without ADHD in other ways.,As illustrated in the scatter plot ( Fig.,"They could even see that the lags in connection development with the two task-related networks -- the frontoparietal and ventral attention networks -- were located primarily in two specific areas of the brain. The new findings mesh well with what other researchers have found by examining the physical structure of the brains of people with and without ADHD in other ways. So, the new findings build on that understanding and add to it.","Results for connections within DMN-DMN are shown in Fig. As illustrated in the scatter plot ( Fig. 2A) , the odds that a strongly maturing connection was lagged (vs. being unlagged) were 6.68 to 1, which is highly statistically significant (P < 0.0001; permutation test).",[1],Psychology,test,1.0,news,http://www.sciencedaily.com/releases/2014/09/140915153607.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29 10.1111/desc.12179,Psychology_easy_367,The words you know are a driving force behind attention.,"Although there was no reliable main effect of Labeling [F(1, 38) = 0.9, p = .34], there was a significant interaction between Labeling and Block [F(1, 38) = 4.4, p < .05], suggesting that the difference between the two labeling conditions was modulated by the repetition of the visual information.","""If you don't know where to look, chances are you don't learn anything. The words you know are a driving force behind attention. ""Our results suggest that language has huge effects, not just on talking, but on attention -- which can determine how children learn, how much they learn and how well they learn,"" Vales said.","There was also a reliable main effect of Block [F(1, 38) = 4.0, p = .05], as RT was overall lower on the second block. Although there was no reliable main effect of Labeling [F(1, 38) = 0.9, p = .34], there was a significant interaction between Labeling and Block [F(1, 38) = 4.4, p < .05], suggesting that the difference between the two labeling conditions was modulated by the repetition of the visual information. There were no other significant interactions.",[1],Psychology,test,1.0,news,http://www.sciencedaily.com/releases/2014/04/140417090838.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29 10.1111/desc.12179,Psychology_easy_369,"""What we've shown is that in 3-year-old children, words activate memories that then rapidly deploy attention and lead children to find the relevant object in a cluttered array,"" said Smith, Chancellor's Professor in the Department of Psychological and Brain Sciences.","Analyses of accuracy yielded a significant main effect of Labeling [F(1, 60) = 7.35, p = .009], with accuracy higher in the Label condition, and a main effect of Discriminability [F (1, 60) = 4.67, p = .03], with accuracy higher in the High Discriminability condition.","""If the name of the target object was also said, the children were much faster at finding it and less distracted by the other objects in the scene,"" Vales, a graduate student in the Department of Psychological and Brain Sciences, said in a recent statement. ""What we've shown is that in 3-year-old children, words activate memories that then rapidly deploy attention and lead children to find the relevant object in a cluttered array,"" said Smith, Chancellor's Professor in the Department of Psychological and Brain Sciences. ""Words call up an idea that is more robust than an image and to which we more rapidly respond.","Accuracy was above 80% for all conditions (see Table 1 for accuracy per condition). Analyses of accuracy yielded a significant main effect of Labeling [F(1, 60) = 7.35, p = .009], with accuracy higher in the Label condition, and a main effect of Discriminability [F (1, 60) = 4.67, p = .03], with accuracy higher in the High Discriminability condition. There was an interaction between Labeling and Discriminability on accuracy [F(1, 60) = 4.34, p = .04], as the difference in accuracy between the two labeling conditions was larger for the Low Discriminability condition.",[1],Psychology,test,1.0,news,http://www.redorbit.com/news/health/1113124549/spoken-language-helps-direct-childrens-eyes-041814/ 10.1177/0013916516628178,Psychology_easy_377,"And there aren't any ""adverse side effects"" with getting organized, so you have nothing to lose.",It is possible that eating behavior that takes place in the midst of a chaotic environment differs from eating behavior that takes place once the individual is removed from that chaotic environment.,"""This should be a fulfilling experience, not a disorienting or traumatizing one,"" said Holly. Then, when they're done physically organizing, they're more energized and excited to organize other components of their lives that they've been disregarding, like their car, email inbox, and calendar."" And there aren't any ""adverse side effects"" with getting organized, so you have nothing to lose.","Furthermore, in the present study, the eating took place after the ""chaos"" had ended, which might not be the case in many real-world situations. It is possible that eating behavior that takes place in the midst of a chaotic environment differs from eating behavior that takes place once the individual is removed from that chaotic environment. An important avenue for future research, therefore, would be to examine the time course of the chaotic-environment/food-intake association.",[1],Psychology,test,1.0,news,http://ct.moreover.com/?a=38381891709&p=1pl&v=1&x=tIWz3pUKqy0s2173JP8XBw 10.1111/jcpp.12015,Psychology_easy_388,"As proof of how normal this all seems to Eliana, now 6, Wolfe recalls the day her daughter told a friend about the surrogacy.","The SDQ discriminates well between psychiatric and nonpsychiatric samples, and evidence for concurrent validity comes from the high correlations between the total score of the SDQ and other assessments of child psychiatric disorder .","That, the 42-year-old Minneapolis mom says, is because she and her husband began explaining things early. As proof of how normal this all seems to Eliana, now 6, Wolfe recalls the day her daughter told a friend about the surrogacy. ""No, you grew in your mom's tummy - everyone does,"" the friend responded.","There was a significant difference between family types for number of siblings, v 2 (6) = 28.84, p < .001, reflecting a lower proportion of surrogacy, egg donation, and donor insemination children than natural conception children with siblings. The SDQ discriminates well between psychiatric and nonpsychiatric samples, and evidence for concurrent validity comes from the high correlations between the total score of the SDQ and other assessments of child psychiatric disorder . Intraclass correlation coefficients ranged from 0.50 to 0.80 .",[1],Psychology,test,1.0,news,http://www.today.com/health/new-study-tracks-emotional-health-surrogate-kids-6C10366818 10.1177/0022427815581858,Psychology_easy_405,"""These results suggest that processing juveniles in the adult system may not uniformly increase offending, as many scholars have thought, and may actually reduce offending in some circumstances,"" Loeffler said.",These results suggest that processing juveniles in the adult system may not uniformly increase offending and may reduce offending in some circumstances.,"The researchers attributed this finding to a combination of enhanced deterrence and incapacitation in the adult justice system. ""These results suggest that processing juveniles in the adult system may not uniformly increase offending, as many scholars have thought, and may actually reduce offending in some circumstances,"" Loeffler said. The results of Loeffler and Grunwald's study, which differed from some of the early empirical literature examining the effects of processing juveniles as adults, adds to a growing number of studies observing that offending among older juveniles is relatively insensitive to the exact legal system in which they are prosecuted.","Based on the rapid onset and limited change in size of these effects over the duration of a 4-year follow-up, and based on the concentration of the effects within a sub-group having the lowest risk of incarceration, we attribute this finding to a combination of enhanced deterrence and incapacitation in the adult justice system. These results suggest that processing juveniles in the adult system may not uniformly increase offending and may reduce offending in some circumstances. Implications for recent state-level changes to the jurisdiction of the juvenile justice system are discussed.",[5],Psychology,test,5.0,news,http://www.technology.org/2015/06/09/processing-arrested-juveniles-as-adults-has-small-effect-on-criminal-recidivism-penn-study-finds/ 10.1016/j.neurobiolaging.2010.10.006,Psychology_easy_407,"""Should this approach prove to to have benefit beyond the period of intervention, it might be applied briefly and intermittently as a prophylactic strategy, an approach that would mitigate many concerns about chronic, severe carbohydrate restriction,"" they concluded.","Should this approach prove to be effective and to have benefit beyond the period of intervention, it might be applied intermittently as a preventive strategy, an approach that would mitigate many concerns about chronic, severe carbohydrate restriction.","Discovering the mechanisms of neural action of the diet, including metabolic and neuroprotective factors in conjunction with neurocognitive effects, ""will be of particular interest and should have implications for understanding the etiology of neurodegeneration,"" they write. ""Should this approach prove to to have benefit beyond the period of intervention, it might be applied briefly and intermittently as a prophylactic strategy, an approach that would mitigate many concerns about chronic, severe carbohydrate restriction,"" they concluded. Dietary ketosis enhances memory in mild cognitive impairment.","Also, demonstrating and distinguishing mechanisms of neural action including metabolic changes and neuroprotective factors in conjunction with neurocognitive effects will be of particular interest and should have implications for understanding the etiology of neurodegeneration. A prominent issue will be duration of the effects and whether there is persistence of benefit beyond the period of active intervention. Should this approach prove to be effective and to have benefit beyond the period of intervention, it might be applied intermittently as a preventive strategy, an approach that would mitigate many concerns about chronic, severe carbohydrate restriction.",[5],Psychology,test,5.0,news,http://psychcentral.com/news/2014/12/08/dietary-ketosis-aids-memory-in-mild-cognitive-impairment/78345.html 10.1007/s10071-014-0832-2,Psychology_easy_412,Cats in the negative group were more likely to alternate their gaze between the screen and the fan than cats in the positive group.,"However, overall, cats in the negative group were significantly more likely to gaze alternate between the screen and the fan than cats in the positive group (glm z = 3.9, P \ 0.001).","The cats also ""changed their behaviour in line with the emotional message given by the owner,"" the paper reads. Cats in the negative group were more likely to alternate their gaze between the screen and the fan than cats in the positive group. The cats in the negative group also began moving sooner than those in the positive group, possibly seeking an escape route.","There was no effect of phase (glm z = 1.7, P = 0.09) and no interaction (glm z = 0.46, P = 0.64) between phase and group on the likelihood of cats showing gaze alternation between the screen and the fan. However, overall, cats in the negative group were significantly more likely to gaze alternate between the screen and the fan than cats in the positive group (glm z = 3.9, P \ 0.001). Results showed no interaction between group and phase (glm Phase 2 z = 1.69, P = 0.09; Phase 3 z = 1.22, P = 0.22; Phase 4 z = 0.42, P = 0.67), but a main effect of both group (glm z = 4.43, P \ 0.001) and phase with cats alternating their gaze significantly less between the screen and the fan in Phase 4 than Phase 1 (glm Phase 4 z = 5.7 P \ 0.001; Phase 2 z = 1.7 P = 0.08; Phase 3 z = 0.02, P = 0.9), and cats in the positive group alternating their gaze between the screen and the fan significantly less than cats in the negative group.",[5],Psychology,test,5.0,news,http://www.mnn.com/family/pets/stories/cats-look-to-their-owners-for-guidance-just-like-dogs 10.1007/s10071-014-0794-4,Psychology_easy_423,"""We suggest that humans notice when magpies occasionally pick up shiny objects because they believe the birds find them attractive, while it goes unnoticed when magpies interact with less eye-catching items,"" she added in a statement.","We suggest that humans notice when magpies occasionally pick up shiny objects because they believe the birds find them attractive, while it goes unnoticed when magpies interact with less eye-catching items.","Instead, all objects prompted responses indicating neophobia - fear of new things - in the birds,"" explained Dr. Shephard. ""We suggest that humans notice when magpies occasionally pick up shiny objects because they believe the birds find them attractive, while it goes unnoticed when magpies interact with less eye-catching items,"" she added in a statement. ""It seems likely, therefore, that the folklore surrounding them is a result of cultural generalization and anecdotes rather than evidence.""","Instead, all objects elicited responses indicating neophobia in free-living birds. We suggest that humans notice when magpies occasionally pick up shiny objects because they believe the birds find them attractive, while it goes unnoticed when magpies interact with less eye-catching items. The folklore may therefore result from observation bias and cultural inflation of orally transmitted episodic events.",[5],Psychology,test,5.0,news,http://www.redorbit.com/news/science/1113214207/magpies-do-not-like-shiny-objects-081814/ 10.1038/s41598-018-26821-7,Psychology_easy_427,"Independent of task, the researchers show that the direction of the effect of autism or psychosis traits on the suppression or rejection of a non-target item is diametrically opposite in the way I suggested above.","Independent of task, we show that the direction of the effect of autism or psychosis traits on the suppression or rejection of a non-target item is diametrical.","As these authors point out, our capacity to attend to a target while ignoring irrelevant distraction affects our ability to successfully interpret what we see. Independent of task, the researchers show that the direction of the effect of autism or psychosis traits on the suppression or rejection of a non-target item is diametrically opposite in the way I suggested above. This approach has the advantage of eliminating the confounding effects of duration of illness, active symptomatology or .","Our capacity to attend a target while ignoring irrelevant distraction impacts our ability to successfully interact with our environment. Independent of task, we show that the direction of the effect of autism or psychosis traits on the suppression or rejection of a non-target item is diametrical. In Study 1, in which the presence of a salient non-target item hindered performance, higher autism traits were associated with better performance, while higher psychosis traits were associated with worse performance.",[5],Psychology,test,5.0,news,http://ct.moreover.com/?a=34205612209&p=1pl&v=1&x=cdTGDqnd_jIObO4NnbvAhQ 10.3102/0002831214544298,Psychology_easy_429,"""Merely attending a more selective college does not make much of a difference for a given student's chance of graduating, if all else remains the same,"" said co-author Paul Attewell.","However, as this article shows, merely attending a more selective college does not make much of a difference for a given student's chances of graduating if all else remains the same.","The findings held true for all students, regardless of whether they appeared likely or unlikely to attend selective schools, as predicted by student background characteristics such as race, gender, socioeconomic status, and pre-college test scores. ""Merely attending a more selective college does not make much of a difference for a given student's chance of graduating, if all else remains the same,"" said co-author Paul Attewell. ""Our findings call into question the argument that a given student should always prefer the most academically selective school to which she can gain admission.""","It is possible that colleges with low graduation rates can make some institutional changes to help their students stay in college and complete their studies. However, as this article shows, merely attending a more selective college does not make much of a difference for a given student's chances of graduating if all else remains the same. We find at best weak evidence that institutions raise, via academic selectivity, the graduation rates of students who otherwise would have lower chances of graduating.",[5],Psychology,test,5.0,news,http://www.sciencedaily.com/releases/2014/08/140807103646.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29 10.1177/1948550617725152,Psychology_easy_438,"According to the study in Social Psychological and Personality Science, ""across most samples and in a meta-analysis, lower neuroticism and higher extraversion, conscientiousness, and openness at baseline were prospectively related to faster gait speed.""","Across most samples and in a meta-analysis, lower neuroticism and higher extraversion, conscientiousness, and openness at baseline were prospectively related to faster gait speed.","Fast Walkers Are More Outgoing Andrew Zaeh for Bustle If someone is a fast walker, there's a good chance they're highly outgoing a and they may even be more conscientious. According to the study in Social Psychological and Personality Science, ""across most samples and in a meta-analysis, lower neuroticism and higher extraversion, conscientiousness, and openness at baseline were prospectively related to faster gait speed."" Slow Walkers Are More Cautious Hannah Burton/Bustle When someone is more inclined towards walking at a slower pace, it may reveal their inner cautiousness.","Across most samples and in a meta-analysis, lower neuroticism and higher extraversion, conscientiousness, and openness at baseline were prospectively related to faster gait speed. In the HRS, lower neuroticism and higher extraversion, conscientiousness, and openness were related to slower gait speed decline. This study provides robust evidence that walking speed in adulthood reflects, in part, the individual's personality.",[5],Psychology,test,5.0,news,http://ct.moreover.com/?a=34903930767&p=1pl&v=1&x=WP_iXs8RwBIi1aTNnOal_g 10.1001/jamapsychiatry.2014.3039,Psychology_easy_439,"Thus, all three versions of DBT were comparably effective at reducing suicidality among individuals at high risk for suicide.","Thus, all 3 versions of DBT were comparably effective at reducing suicidality among individuals at high risk for suicide.","""Contrary to our expectations, standard DBT was not superior to either comparison condition for any suicide-related outcome, and no significant differences were detected between DBT-S and DBT-I. Thus, all three versions of DBT were comparably effective at reducing suicidality among individuals at high risk for suicide. ... More research is needed before strong conclusions can be made as to what is the best DBT intervention for highly suicidal individuals,"" the study concludes.","Contrary to our expectations, standard DBT was not superior to either comparison condition for any suicide-related outcome, and no significant differences were detected between DBT-S and DBT-I. Thus, all 3 versions of DBT were comparably effective at reducing suicidality among individuals at high risk for suicide. In contrast, findings suggested that DBT interventions that included DBT skills training (standard DBT and DBT-S) were more effective in reducing NSSI acts and improving other mental health problems than a DBT intervention without skills training (DBT-I).",[5],Psychology,test,5.0,news,http://www.sciencedaily.com/releases/2015/03/150325132516.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Fmost_popular+%28Most+Popular+News+--+ScienceDaily%29 10.1016/j.bbi.2011.08.007,Psychology_easy_501,SOURCE: Saxena et al.,"Furthermore, these dysfunctional immune responses are associated with increased impairments in behaviors characteristic of core features of ASD, in particular, deficits in social interactions and communication.","Since the immune system effects that Saxena and colleagues examined likely take place very early on in fetal development, the find does not seem to lend credence to the popular theory linking childhood vaccines and autism, which lacks scientific support. ""Furthermore, these dysfunctional immune responses are associated with increased impairments in behaviors characteristic of core features of [autism spectrum disorder], in particular, deficits in social interactions and communication,"" the UC Davis scientists wrote. SOURCE: Saxena et al.","Furthermore, these dysfunctional immune responses are associated with increased impairments in behaviors characteristic of core features of ASD, in particular, deficits in social interactions and communication. This review will discuss the current state of our knowledge of immune dysfunction in ASD, how these findings may impact on underlying neuro-immune mechanisms and implicate potential areas where the manipulation of the immune response could have an impact on behavior and immunity in ASD. There is a concordance rate for ASD of 0-37% reported for dizygotic twins, while concordance rates of 44-91% are reported for monozygotic twins (Bailey et al., 1995; Constantino and Todd, 2000; Kates et al., 2004; Steffenburg et al., 1989) , suggesting that genetic composition may contribute to increased risk of developing ASD.",[1],Psychology,test,1.0,news,http://www.ibtimes.com/more-evidence-immune-system-role-autism-927239 10.1037/a0018438,Psychology_easy_525,It is precisely the otherworldly spiritualism that seems to shroud so many ancient spiritual traditions that compels us to believe their assertions.,"It is important to note that whereas no other studies have reported depletion of WMC over the predeployment period, there is ample evidence of degradation in other cognitive functions as well as changes in negative and positive affect during this interval in other cohorts .","Placebo effects are both real and beneficial, and the relaxation that stems from chanting mantras may be therapeutic in and of itself. Furthermore, mindfulness meditation--a variant that stems from the Buddhist tradition and involves fostering a nonjudgmental awareness of the present moment--was found by Goyal's group to decrease anxiety and depression. It is precisely the otherworldly spiritualism that seems to shroud so many ancient spiritual traditions that compels us to believe their assertions.","These are striking, given that the intention of predeployment training is to cognitively, physically, and emotionally prepare service members for deployment. It is important to note that whereas no other studies have reported depletion of WMC over the predeployment period, there is ample evidence of degradation in other cognitive functions as well as changes in negative and positive affect during this interval in other cohorts . Although our study was concerned with exploring whether MT might provide prophylaxis from functional impairments experienced in specific military contexts, the protective effects of MT observed herein suggest that MT might be effective as a resilience training protocol more generally.",[1],Psychology,test,1.0,news,http://qz.com/191925/the-scant-science-behind-anything-that-claims-to-boost-your-brainpower/ 10.1371/journal.pone.0073791,Psychology_easy_534,"When the two genders are speaking to each other, they try to meet in the middle: ""Males use uh about 14 percent less often when talking with a female rather than a male, and females use uh about about 20 percent more often when talking with a male rather than a female,"" Liberman writes.",Gender provides a familiar and easy to understand proof of concept for open-vocabulary analysis.,"Usage of 'Uh' and 'Um' Among Men and Women Overall, he found that women say ""um"" 22 percent more than men do, but men say ""uh"" more than twice as often as women do. When the two genders are speaking to each other, they try to meet in the middle: ""Males use uh about 14 percent less often when talking with a female rather than a male, and females use uh about about 20 percent more often when talking with a male rather than a female,"" Liberman writes. (There's not nearly as much accommodation with ""um."")","This is not too surprising since openness exhibits the most variation across conditions of other studies (for examples, see ), and its component traits are most loosely related . Gender provides a familiar and easy to understand proof of concept for open-vocabulary analysis. All results are significant at Bonferroni-corrected pv0:001.",[1],Psychology,test,1.0,news,http://www.theatlantic.com/health/archive/2014/08/men-say-uh-and-women-say-um/375729/ 10.1126/science.1224000,Psychology_easy_536,"""Dr. Ingber's work was ideally suited for Trestles in that he had developed an innovative model on lab-scale computational resources, but the computational demands of his research outgrew what was possible on his local resources,"" said Glenn K. Lockwood, a user services consultant with SDSC.","However, the majority of spikefield interactions involving identity selective units come from cells recorded in areas LIP, PG and to a lesser extent MIP.","In using SDSC's Trestles cluster, Ingber was able to complete a month's worth of processing in only six hours. ""Dr. Ingber's work was ideally suited for Trestles in that he had developed an innovative model on lab-scale computational resources, but the computational demands of his research outgrew what was possible on his local resources,"" said Glenn K. Lockwood, a user services consultant with SDSC. Ultimately, Lockwood wanted to ensure that Ingber's research was not slowed by the transition from computing on lab-scale resources to using national-scale resources.","(PFC unit -PPC lfp pairs were not included due to small sample sizes.) However, the majority of spikefield interactions involving identity selective units come from cells recorded in areas LIP, PG and to a lesser extent MIP. Our findings demonstrate that fronto-parietal synchronization during visual working memory is widespread, task-dependent and content specific during the delay period.",[1],Psychology,test,1.0,news,http://www.newswise.com/articles/the-mechanism-of-short-term-memory 10.1016/j.tics.2018.01.004,Psychology_easy_549,"Facebook is in crisis mode, but the company can take major steps to fix itself - and the global community it says it wants to promote.","Maintaining beliefs and judgments that are aligned with one's political identity therefore is a higher priority than achieving accuracy, and people with the highest reasoning abilities are better able to use efficient strategies to do that, as compared to people with lowest reasoning abilities.","Facebook is in crisis mode, but the company can take major steps to fix itself - and the global community it says it wants to promote. Facebook founder, CEO and majority shareholder Mark Zuckerberg need not wait for governments to impose regulations. If he and other industry leaders wanted to, they could make meaningful changes fairly quickly.","However, their personal positions on these policies or issues have strong consequences for their social identity. Maintaining beliefs and judgments that are aligned with one's political identity therefore is a higher priority than achieving accuracy, and people with the highest reasoning abilities are better able to use efficient strategies to do that, as compared to people with lowest reasoning abilities. In the control condition, people who were strong at math were able to effectively solve an analytical problem.",[1],Psychology,test,1.0,news,http://ct.moreover.com/?a=37980457180&p=1pl&v=1&x=d_PDCoIsM57Ihhy65l8chQ 10.1177/0956797614542274,Psychology_easy_553,Five minutes three times a week is manageable.,"Additionally, the more participants rated their conversations as ordinary, the more they underestimated their curiosity, r (48)","It doesn't have to happen every day, but you should find some sort of structure. Five minutes three times a week is manageable. Four hours daily is not, unless you're making your living as a writer.","Similarly, participants' predictions of how interesting they would find the experience of reading what they had documented (M = 3.48, SD = 1.31) were lower than their actual ratings of interest at Time 2 (M = 4.66, SD = 1.58), t(47) = 4.70, p < .001, d = 0.81. Additionally, the more participants rated their conversations as ordinary, the more they underestimated their curiosity, r (48) Study 2 replicated the primary results from Study 1: Individuals underestimated the value of rediscovering current experiences in the future.",[1],Psychology,test,1.0,news,http://ct.moreover.com/?a=33973360420&p=1pl&v=1&x=NMU7Pxp1H8prxaBtkiFAmw 10.1016/j.jenvp.2013.12.006,Psychology_easy_555,"A daily reminder of our carbon output, displayed on a meter in the garage or near the back door, would make it much harder to be oblivious--and might even inspire new behaviors.","Agreement between coders was initially high (r ¼ 0.90, p < 0.001) and further discussion resolved discrepancies.","""We suggest that costs are not ignored in communications (designed to discourage energy usage),"" they write, ""but that environmental considerations should also be highlighted."" It seems like a sound idea. A daily reminder of our carbon output, displayed on a meter in the garage or near the back door, would make it much harder to be oblivious--and might even inspire new behaviors.","). Agreement between coders was initially high (r ¼ 0.90, p < 0.001) and further discussion resolved discrepancies. Exploring frequency of codes between HEC conditions showed that participants often mentioned both financial and environmental reasons, emerging as the highest category in both energy and cost conditions, see Fig.",[1],Psychology,test,1.0,news,http://www.psmag.com/navigation/nature-and-technology/much-carbon-emit-today-82635/ 10.1086/678485,Psychology_easy_593,"Meanwhile, the effect was attenuated when the new product was difficult to visualize (when they were non-runners unfamiliar with heart rate monitors, when the vacation destination was very unfamiliar, or when the less visualizable features of Google Glass were emphasized).","When participants were asked to relate the product to the past, concrete visualization aids led to marginally higher product evaluations (M concrete p 5.77 vs. M abstract p 4.91; F(1, 107) p 3.14, p p .07).","However, this effect was strongest when it was easier for consumers to visualize using a new product (when they were regular runners familiar with heart rate monitors, when they knew something about a vacation destination, or when the more visualizable features of Google Glass were emphasized). Meanwhile, the effect was attenuated when the new product was difficult to visualize (when they were non-runners unfamiliar with heart rate monitors, when the vacation destination was very unfamiliar, or when the less visualizable features of Google Glass were emphasized). When a product was highly familiar to consumers (not a new product), the effect was reversed because prior images of using the product interfered with their visualization.","Follow-up contrasts showed that when participants were asked to relate the product to the future, abstract visualization aids led to marginally higher product evaluations than concrete visualization aids (M abstract p 5.87 vs. M concrete p 5.04; F(1, 107) p 2.98, p p .08). When participants were asked to relate the product to the past, concrete visualization aids led to marginally higher product evaluations (M concrete p 5.77 vs. M abstract p 4.91; F(1, 107) p 3.14, p p .07). When the new product was positioned as relatively hard to visualize (i.e., emphasizing the weather, map, and e-mail functions), we found no interaction between time and visualization aids (F(1, 108) zation aids, and ease of visualization on product evaluations (95% CI: .1350 to 1.5681, change of three-way interaction in significance after controlling for the mediator: b p 1.45, t(214) p 1.49, p p .14 vs. b p 2.17, t(215) p 2.14, p !",[1],Psychology,test,1.0,news,http://www.sciencedaily.com/releases/2015/01/150122084348.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29 10.1016/j.trf.2015.07.016,Psychology_easy_600,"To the surprise of Thomas and Walker, who suspected that weather might make non-drivers frequently adjust their travel patterns, participants who commuted by bike or on foot showed significantly stronger habits than those who traveled by bus or car.",The group centroids are shown in Table 2 below.,"But it turns out drivers aren't the only ones whose brains get beholden to a certain manner of commuting. To the surprise of Thomas and Walker, who suspected that weather might make non-drivers frequently adjust their travel patterns, participants who commuted by bike or on foot showed significantly stronger habits than those who traveled by bus or car. On a scale from 1 to 7, with 7 being the strongest, walkers and cyclists each rated their commuting habit at roughly 5.2.","Accordingly, the discriminant function analysis here revealed 3 functions that significantly contributed to group separation. The group centroids are shown in Table 2 below. [PLEASE INSERT TABLE 2 HERE] Table 2 shows bicycling to be strongly associated with higher positivity, higher arousal and low relaxation.",[1],Psychology,test,1.0,news,http://www.citylab.com/commute/2015/09/why-cyclists-form-stronger-commuting-habits-than-drivers/403069/ 10.1186/s12888-016-1075-3,Psychology_easy_601,"O problema tambem pode se manifestar de forma aguda, sendo causada por stress, depressao, distracao na hora de dormir (como o uso de dispositivos eletronicos), gastrite, consumo de cafeina e alcool.","Australian populations, which might result from the limited number of included studies (two studies comprising 13,323 participants).","Estima-se que 10% das pessoas no mundo tenham essa variante. O problema tambem pode se manifestar de forma aguda, sendo causada por stress, depressao, distracao na hora de dormir (como o uso de dispositivos eletronicos), gastrite, consumo de cafeina e alcool. A principal causa desta manifestacao sao conflitos emocionais passageiros ou de longa duracao.","However, no statistically significant association was observed in Abbreviations: BMI body mass index, dur duration criterion, day daytime consequences criterion, F female, M male, NA not available, SES socioeconomic status, Sd sleep difficulties criterion *Study population truly or somewhat representative of a community or population-based study defined as general population, and study population was sampled from a special population (such as population from a company, register patients, data from the health insurance company or health examination organization or pregnant), which defined as non-general populations Australian populations, which might result from the limited number of included studies (two studies comprising 13,323 participants). In order to make the finding generalize to other populations, more studies are warranted to be conducted in other populations from Asia, Africa and South America.",[1],Psychology,test,1.0,news,http://ct.moreover.com/?a=37619882310&p=1pl&v=1&x=0_HNWbnV6_o0oBF3Euqp7w 10.1073/pnas.1612881114,Psychology_easy_607,"That's a pretty substantial bump.""","There was firm support for H1 for the large red/yellow pair (7.5RP-10Y, columns 38-12), t (9) =2.84, p=.02, B=6.30E+00 and for H0 for the larger hue differences within green (7.5GY-2.5BG, columns 24-30) or blue (10BG-5PB, columns 15-21), (largest t=1.34, smallest p=0.21, largest B=0.17).","""That value goes up to just under 1.5 billion euros under a new ecosystem-based management. That's a pretty substantial bump."" While it might seem counterintuitive that increased stocks of one species would drive up the capital value of another species, the predators and prey within an ecosystem have a complementary relationship.","). There was firm support for H1 for the large red/yellow pair (7.5RP-10Y, columns 38-12), t (9) =2.84, p=.02, B=6.30E+00 and for H0 for the larger hue differences within green (7.5GY-2.5BG, columns 24-30) or blue (10BG-5PB, columns 15-21), (largest t=1.34, smallest p=0.21, largest B=0.17). We identify stimulus 10Y, 2.5Y and 7.5GY as 'yellow' here due to Munsell hue notation, although at the munsell value sampled, these hues are darker than prototypical yellow.",[1],Psychology,test,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/W4tOBRM8BJs/