copenlu/druid huggingface dataset:
Claim: “Mayo Clinic study shows Pfizer vaccine dropped to 42% effective.” (Instagram posts, 2021-08-12)
Evidence (2021-08-13): Researchers from the Mayo Clinic in Minnesota, US, found that the Pfizer-BioNTech vaccine was only 42 per cent effective against infection in July, while the Moderna vaccine was only 76 percent effective, the Daily Mail reported. "Comparing rates of infection between matched individuals fully vaccinated with mRNA-1273 (Moderna Covid vaccine) versus BNT162b2 (Pfizer Covid vaccine) across Mayo Clinic Health System sites in multiple states (Minnesota, Wisconsin, Arizona, Florida, and Iowa). mRNA-1273 conferred a two-fold risk reduction against breakthrough infection compared to BNT162b2," the researchers wrote in the study, not yet peer reviewed, and published on pre-printer server medRxiv.org. [...] Last month, Pfizer published data which showed that its vaccine's efficacy drops to 86 percent after six months.
Claim: “Mayo Clinic study shows Pfizer vaccine dropped to 42% effective.” (Instagram posts, 2021-08-12)
Evidence (2021-08-12): - The study found Pfizer effectiveness dropped to 42% when Delta became the dominant strain. [...] Pfizer's coronavirus vaccine may not be as good at preventing infection with the Delta variant as Moderna's, according to a new preprint from the Mayo Clinic and analytics company nference. [...] During that month in Minnesota, Pfizer's effectiveness against COVID-19 infection dropped to 42% while Moderna's dropped less dramatically to 76% effectiveness.
Claim: “Mayo Clinic study shows Pfizer vaccine dropped to 42% effective.” (Instagram posts, 2021-08-12)
Evidence (2021-08-12): - It found Pfizer's effectiveness dropped to 42% in Minnesota in July, when Delta became dominant. [...] Pfizer's coronavirus vaccine might not be as good at preventing infection of the Delta variant as Moderna's, according to a new preprint from the Mayo Clinic and the analytics company Nference. [...] During that month in Minnesota, Pfizer's effectiveness against COVID-19 infection dropped to 42%, while Moderna's dropped less dramatically to 76%.
Claim: “Mayo Clinic study shows Pfizer vaccine dropped to 42% effective.” (Instagram posts, 2021-08-12)
Evidence (2024-09-12): In December 2020, the Pfizer-BioNTech COVID-19 vaccine two-dose series was found to be both safe and effective in preventing COVID-19 infection in people age 18 and older. This data helped predict how well the vaccines would work for younger people. The effectiveness varied by age. Since 2020, the vaccine has been updated yearly to better protect against the strains of COVID-19 spreading in the community. The currently approved vaccine is Pfizer-BioNTech COVID-19 vaccine 2024-2025 formula. The Pfizer-BioNTech vaccine is approved under the name Comirnaty for people age 12 and older. The FDA authorized the vaccine for people age 6 months to 11 years. The number of shots in this vaccination series varies based on a person's age and COVID-19 vaccination history. [...] But vaccines are not 100% effective. So taking other action to lower your risk of getting COVID-19 still helps protect you and others from the virus. These steps are even more important when you're in an area with a high number of people with COVID-19 in the hospital. Protection also is important as time passes since your last vaccination.
Claim: “Mayo Clinic study shows Pfizer vaccine dropped to 42% effective.” (Instagram posts, 2021-08-12)
Evidence (2021-08-11): A new preprint study published in medRxiv suggests mRNA vaccines' efficacy against infection—particularly the Pfizer-BioNTech vaccine—has dropped significantly since the delta variant became widespread, although the vaccines' protection against hospitalization and death remain strong. [...] However, during the month of July, the vaccines' efficacy against infection appeared to decline in Minnesota, where the prevalence of the delta variant had increased from 0.7% in January to 70% in July. Specifically, the researchers found that during July, the Moderna vaccine appeared to have an estimated efficacy of 76% against infection, while the Pfizer-BioNTech vaccine had an estimated efficacy of 42% against infection. [...] However, Venky Soundararajan, a lead author on the study, said based on the data compiled so far, the vaccines' reduced efficacy likely stems from "a combination" of both reduced efficacy over time and reduced efficacy against the delta variant. "The Moderna vaccine is likely—very likely—more effective than the Pfizer vaccine in areas where delta is the dominant strain, and the Pfizer vaccine appears to have a lower durability of effectiveness," he said.
Claim: “Mayo Clinic study shows Pfizer vaccine dropped to 42% effective.” (Instagram posts, 2021-08-12)
Evidence (2024-01-01): Are vaccines becoming less effective at preventing Covid infection?
Claim: “Mayo Clinic study shows Pfizer vaccine dropped to 42% effective.” (Instagram posts, 2021-08-12)
Evidence (2021-08-11): What they're saying: The study found the Pfizer vaccine was only 42% effective against infection in July, when the Delta variant was dominant. "If that's not a wakeup call, I don't know what is," a senior Biden official told Axios. Driving the news: The study, conducted by nference and the Mayo Clinic, compared the effectiveness of the Pfizer and Moderna vaccines in the Mayo Clinic Health System over time from January to July. [...] Moderna was 76% effective against infection, and Pfizer was only 42% effective.
Claim: “Mayo Clinic study shows Pfizer vaccine dropped to 42% effective.” (Instagram posts, 2021-08-12)
Evidence (2021-08-12): "BREAKING: Biden Admin Concerned as Mayo Clinic Study Shows Pfizer Vaccine Dropped to 42% Effective." [...] An Instagram post claims: "Mayo Clinic study shows Pfizer vaccine dropped to 42% effective." [...] Human Events, "Biden Admin Concerned as Mayo Clinic Study Shows Pfizer Vaccine Dropped to 42% Effective," Aug. 11, 2021
Claim: “Mayo Clinic study shows Pfizer vaccine dropped to 42% effective.” (Instagram posts, 2021-08-12)
Evidence (2021-09-24): In presenting their rationale for the decision on Aug. 18, health officials pointed to multiple recent studies conducted in the U.S. that have suggested a decline in the real-world effectiveness of the Pfizer/BioNTech or Moderna vaccines in preventing any kind of lab-confirmed infection. [...] An unpublished study of patients in the Mayo Clinic Health System compared the two mRNA vaccines and found the Pfizer/BioNTech vaccine began with an effectiveness of 76% against any kind of PCR-confirmed infection in January that fell to 42% in July. The drop for Moderna was smaller, from 86% to 76%. [...] Notably, however, officials said there was not much evidence that the vaccines were working less well in protecting against severe disease. The New York study, for example, found that vaccine protection against hospitalization remained at 90% or higher for each week analyzed. And another MMWR report, which drew on hospital information from 18 states, found the Pfizer/BioNTech and Moderna vaccines stayed 84% to 86% effective in preventing hospitalization for 24 weeks.
Claim: “Mayo Clinic study shows Pfizer vaccine dropped to 42% effective.” (Instagram posts, 2021-08-12)
Evidence (2021-08-19): They cited three new studies, released by the Centers for Disease Control and Prevention, that showed their protection against Covid diminished over several months. One study in New York from May 3 through July 25 showed that vaccine protection against infection dropped from around 92% to 80%. Another study by the Mayo Clinic showed that Pfizer's vaccine efficacy fell from around 76% to 42% while Moderna's declined from 86% to 76%. "Taken together, you can see that while the exact percentage of vaccine effectiveness over time differs depending on the cohort and settings study, the data consistently demonstrate a reduction of vaccine effectiveness against infection over time," Walensky told reporters during a White House Covid press briefing. [...] Israel, a country U.S. officials have also cited in their push for boosters, has begun giving out third doses to the elderly after new data showed a reduction in the effectiveness of Pfizer's Covid vaccine against severe illness among people 65 and older who were fully vaccinated in January or February.
Claim: “Mayo Clinic study shows Pfizer vaccine dropped to 42% effective.” (Instagram posts, 2021-08-12)
Evidence (2021-08-17): "Factors that may decrease vaccine response among immunocompromised populations include older age, primary immune deficiency, lower lymphocyte counts, decreased kidney function, being on immunosuppressive drugs or high dose corticosteroids and current or recent cancer treatment," she said. "For example, a study looking at mRNA vaccine effectiveness in immunocompromised populations found 59–71% effectiveness against infection for immunocompromised people versus 90–94% overall.
Claim: “Mayo Clinic study shows Pfizer vaccine dropped to 42% effective.” (Instagram posts, 2021-08-12)
Evidence (2021-08-18): The effectiveness of the vaccines declined from about 92% to 80% in reducing cases, the study, which was published by the CDC, showed. [...] Another study, conducted by the Mayo Clinic, analyzed vaccine effectiveness for both the Pfizer and Moderna vaccines among more than 80,000 people across all ages using data through July 16, Walensky said, adding, "Like we saw in the New York data, vaccine effectiveness against infection declined over time." The Mayo Clinic study found that effectiveness fell from 76% to 42% among those who received the Pfizer vaccine and from 86% to 76% among those who received the Moderna vaccine. "These data are currently available on a pre-print server," Walensky said.
Claim: “Mayo Clinic study shows Pfizer vaccine dropped to 42% effective.” (Instagram posts, 2021-08-12)
Evidence (2021-08-11): Mayo Clinic research finds both inoculations have dropped in efficacy, but Pfizer’s decline has been much steeper; both remain highly effective against severe illness [...] However, one was still far more effective than the other — while Moderna was down to 76 percent, Pfizer was down to 42%. The study was conducted among over 50,000 patients. [...] The Mayo Clinic study found that across multiple states, those inoculated with Pfizer were twice as likely to experience a breakthrough infection despite being vaccinated, as compared to Moderna.
Claim: “Mayo Clinic study shows Pfizer vaccine dropped to 42% effective.” (Instagram posts, 2021-08-12)
Evidence (2021-08-12): Early findings posted ahead of rigorous peer review suggested the Pfizer COVID-19 vaccine declined to 42% effectiveness against infection amid sweeping spread of the delta variant, with the Moderna vaccine declining to 76%. [...] While results indicated the Pfizer and Moderna vaccines were highly effective against COVID-19 infection (76%, 86%, respectively) and hospitalization (85%, 91.6%) the effectiveness against infection dropped by July to 42% and 76%, respectively. [...] Study authors suggested several factors behind the differences observed among the Pfizer and Moderna vaccines, including the dosing, meaning "each mRNA-1273 [Moderna] dose provides three times more mRNA copies of the Spike protein than BNT162b2 [Pfizer], which could result in more effective priming of the immune response."
Claim: “Mayo Clinic study shows Pfizer vaccine dropped to 42% effective.” (Instagram posts, 2021-08-12)
Evidence (2021-08-08): Although clinical trials and real-world studies have affirmed the effectiveness and safety of the FDA-authorized COVID-19 vaccines, reports of breakthrough infections and persistent emergence of new variants highlight the need to vigilantly monitor the effectiveness of these vaccines. Here we compare the effectiveness of two full-length Spike protein-encoding mRNA vaccines from Moderna (mRNA-1273) and Pfizer/BioNTech (BNT162b2) in the Mayo Clinic Health System over time from January to July 2021, during which either the Alpha or Delta variant was highly prevalent. We defined cohorts of vaccinated and unvaccinated individuals from Minnesota (n = 25,589 each) matched on age, sex, race, history of prior SARS-CoV-2 PCR testing, and date of full vaccination. Both vaccines were highly effective during this study period against SARS-CoV-2 infection (mRNA-1273: 86%, 95%CI: 81-90.6%; BNT162b2: 76%, 95%CI: 69-81%) and COVID-19 associated hospitalization (mRNA-1273: 91.6%, 95% CI: 81-97%; BNT162b2: 85%, 95% CI: 73-93%). However, in July, the effectiveness against infection was considerably lower for mRNA-1273 (76%, 95% CI: 58-87%) with an even more pronounced reduction in effectiveness for BNT162b2 (42%, 95% CI: 13-62%).
Claim: “Mayo Clinic study shows Pfizer vaccine dropped to 42% effective.” (Instagram posts, 2021-08-12)
Evidence (2021-08-17): First, some background to help put this in context. Operation Warp Speed led to the development of two novel mRNA vaccines (Pfizer and Moderna), one adenovirus vaccine (Johnson and Johnson) and others not available in the USA at this time. The mRNA vaccines produced remarkable results with protection against COVID in the 94-95% range. The J&J vaccine was in the 70% range, which is similar to what we see for annual flu shots. Over time, it was expected that the protective benefits of the vaccine would decrease as they do for all vaccines. Indeed, a Mayo clinic study shows that in July 2021 Moderna protection had decreased to 76% and Pfizer had dropped to 42%. However, both remained highly effective at protecting against severe illness that can result in hospitalizations, placement in Intensive Care Units or death. Those who are immunocompromised – including people being actively treated for cancers or who have received an organ transplant and are taking medicine to suppress their immune system – do not get the same robust response to the vaccine. After receiving their series of Pfizer or Moderna vaccines, they are protected in the range of 59% compared to the 94-95% range for the population at large. Studies have shown that a third dose can increase the number of antibodies and offer additional protection against the COVID virus.
Claim: “Mayo Clinic study shows Pfizer vaccine dropped to 42% effective.” (Instagram posts, 2021-08-12)
Evidence (2021-08-24): Pfizer CEO Albert Bourla was confident in June about the ability of his company’s vaccine to protect against the highly contagious delta variant, as it marched across the globe and filled U.S. hospitals with patients. [...] Just weeks later, Pfizer said it would seek authorization for a booster shot, after early trial results showed a third dose potentially increased protection. At the end of July, Pfizer and BioNTech announced findings that four to six months after a second dose, their vaccine’s efficacy dropped to about 84%. [...] Yet the effectiveness of the Pfizer vaccine against variants is still under debate. This month a new preprint study by the Mayo Clinic found that the product’s effectiveness against infection dropped to 42% from January to July ― as the delta variant’s prevalence markedly increased.
Claim: “Mayo Clinic study shows Pfizer vaccine dropped to 42% effective.” (Instagram posts, 2021-08-12)
Evidence (2021-08-12): Mayo Clinic researchers are reporting a "pronounced reduction" this summer in the effectiveness of the Pfizer COVID-19 vaccine at preventing coronavirus infections, but still a high level of protection against severe illnesses and hospitalizations. [...] Examining records for 25,000 vaccinated and unvaccinated Mayo patients in Minnesota, the researchers reported 76% effectiveness in the Pfizer vaccine protecting them from infection this year, but only 42% effectiveness in July amid the emergence of a more transmissible delta variant. The comparable effectiveness of the Moderna vaccine declined from 86% to 76%. [...] The effectiveness of the Pfizer and Moderna vaccines at preventing hospitalizations was 85% and 91%, respectively, during the entire year, so their performance in July alone was slightly worse.
Claim: “Mayo Clinic study shows Pfizer vaccine dropped to 42% effective.” (Instagram posts, 2021-08-12)
Evidence (2021-08-11): The mRNA vaccine from Pfizer and BioNTech may be less effective than Moderna's against the Delta variant of the coronavirus, according to two reports posted on medRxiv on Sunday ahead of peer review. In a study of more than 50,000 patients in the Mayo Clinic Health System, researchers found the effectiveness of Moderna's vaccine against infection had dropped to 76% in July - when the Delta variant was predominant - from 86% in early 2021. Over the same period, the effectiveness of the Pfizer/BioNTech vaccine had fallen to 42% from 76%, researchers said. While both vaccines remain effective at preventing COVID hospitalization, a Moderna booster shot may be necessary soon for anyone who got the Pfizer or Moderna vaccines earlier this year, said Dr. Venky Soundararajan of Massachusetts data analytics company nference, who led the Mayo study. (Aug. 9) [...] New research offers encouraging evidence about how the Johnson & Johnson vaccine stacks up against its competitors — and the delta variant — according to infectious-disease specialists. However, there are still lingering questions about booster shots. Earlier clinical trials showed the Johnson & Johnson vaccine was 66 percent effective overall in preventing moderate to severe disease four weeks after the shot, with effectiveness varying depending on location. Its competitors from Pfizer and Moderna, on the other hand, recorded 90 percent-plus effectiveness against the coronavirus. Anthony S. Fauci, the nation’s leading infectious-disease expert, has said all three vaccines are effective. (Beachum, Bever and Iati, 8/10)
Claim: Joe Biden "already has what is the most progressive platform of any major party nominee in history." (Barack Obama, 2020-04-14)
Evidence (2020-04-14): This is a complicated assertion to evaluate, because the nature of liberalism changes over time, making candidate-to-candidate comparisons difficult. If you compare Biden’s platform to an absolute concept of liberalism, it is the most progressive. Tracking shifts within his party, Biden has moved to the left compared with where Obama and some previous Democratic nominees stood. In his own time, though, Biden is hardly in his party’s ideological vanguard, at least compared with previous nominees such as George McGovern.
Claim: Joe Biden "already has what is the most progressive platform of any major party nominee in history." (Barack Obama, 2020-04-14)
Evidence (2024-06-07): The "shock" is the gift that keeps giving progressives an excuse to socialize the economy through government "partnerships." While denouncing "tax breaks" for "Big Pharma" and "Big Oil," Biden (notes the Cato Institute’s Chris Edwards) favors trillions of dollars for "Big Semiconductor, Big Wind, Big Solar, Big Battery, Big Automaker, Big Utility." [...] Biden says, more earnestly than grammatically, "Every American willing to work hard should be able to get a job no matter where they are … and keep their roots where they grew up." So, government planning will render geographic mobility, hitherto a source of national vitality and modernity, optional: Stasis is an entitlement. Already Americans are only half as likely to move between states as they were in 1980.
Claim: Joe Biden "already has what is the most progressive platform of any major party nominee in history." (Barack Obama, 2020-04-14)
Evidence (2024-08-26): Sanders still wants to tax billionaires, level the economic playing field, and push a left-wing platform.
Claim: Joe Biden "already has what is the most progressive platform of any major party nominee in history." (Barack Obama, 2020-04-14)
Evidence (2020-07-08): Throughout the Democratic primary, Biden stuck to a more moderate platform, while Sanders, Massachusetts Sen. Elizabeth Warren and much of the rest of the crowded field courted progressives and advocated for broader structural changes. But as the United States faces a growing pandemic and unemployment rates at the highest levels in generations, Biden has been talking more and more about a presidency that approaches Franklin Delano Roosevelt's, with bold progressive ambitions. [...] "The goals of the task force were to move the Biden campaign into as progressive a direction as possible, and I think we did that," Sanders told NPR. "On issue after issue, whether it was education, the economy, health care, climate, immigration, criminal justice, I think there was significant movement on the part of the Biden campaign." [...] Sanders hopes this document will get more progressives excited about the goals, not just the existence, of a Biden administration. "When I talked to Joe a while back, he said that he wants to be the most progressive president since FDR," Sanders said. "Do I believe that Biden believes that now is the time for bold action to protect the working class and lower-income people in this country? Yes, I do believe that's the case."
Claim: Joe Biden "already has what is the most progressive platform of any major party nominee in history." (Barack Obama, 2020-04-14)
Evidence (2020-09-21): The reality of Biden’s policy proposals stands in sharp contrast to a campaign that has positioned him as a centrist Democrat. His platform reflects the triumph of the progressive left and would mark a substantial increase in the size and scope of the federal government. If Biden is elected and signs into law even a fraction of what he’s proposed, he would govern as an unabashed progressive and would be one of the most liberal presidents in American history. [...] It’s fair to argue that Biden’s plans aren’t as progressive as those proposed by some of his competitors for the Democratic nomination (Warren backed $30 trillion in tax hikes), or by some progressives in Congress. But the size and scope of his proposals dwarf those of recent Democratic nominees for president. His budget is one of the most progressive in recent campaign history and more than double the one proposed by Hillary Clinton in 2016. [...] It’s easy to ignore policy discussions during a presidential campaign, particularly when so much mudslinging is going on. But a closer look at Joe Biden’s platform reveals some important indicators of the progressive policies he will pursue, if elected. Those who think they’ll get a moderate in the White House should think again.
Claim: Joe Biden "already has what is the most progressive platform of any major party nominee in history." (Barack Obama, 2020-04-14)
Evidence (2024-04-11): Progressive Democrats already have identified a list of issues where they hope to influence the party platform, including calling for filibuster reform in the Senate, declaring a national climate emergency and ending private funding of elections. But the war in the Gaza Strip and potential conditions on future U.S. military assistance to Israel is poised to be the most contentious as Democrats prepare for their convention this August. [...] In 2012, the DNC members debated taking steps toward including language endorsing same-sex marriage before President Obama had taken that position publicly, though he ultimately did that well before the convention. In 2016, Sanders leveraged his significant tranche of delegates to pressure Hillary Clinton on a wide range of progressive policy priorities, from climate change to student debt to international trade treaties, resulting in the most progressive platform in the parties’ history. [...] In 2020, the Biden team largely headed off a platform fight by creating so-called Unity Task Forces, composed of both Biden and Sanders surrogates, which produced draft language for the party platform signed off by both camps. Those recommendations ultimately telegraphed a more robust, progressive policy agenda that went beyond what Biden had proposed in his primary campaign.