copenlu/druid huggingface dataset:
Claim: Peanut allergies are caused by the peanut oil in vaccines (Matt Roeske, 2024-07-22)
Evidence (2021-01-01): Food allergy is a growing public health epidemic with few available treatments beyond allergen avoidance and rescue medications for accidental exposures. A major focus of therapeutic development for food allergies is allergen-specific immunotherapy (AIT) in which patients are exposed to increasing amounts of allergen in controlled dosing to induce desensitization or tolerance. The work of the past few decades has culminated in the recent FDA approval of a peanut product for oral AIT for peanut allergies. Despite these advances, current AIT protocols are cumbersome, take a long time to reach clinical benefit and often have significant side effects. Therefore, there is a great need to develop new therapeutics for food allergy. One area of research aims to improve AIT through the use of adjuvants which are substances traditionally added to vaccines to stimulate or direct a specific immune response. Adjuvants that induce Th1-polarized and regulatory immune responses while suppressing Th2 immunity have shown the most promise in animal models. The addition of adjuvants to AIT may reduce the amount and frequency of allergen required to achieve clinical benefit and may induce more long-lasting immune responses. [...] Mucosal Nanoemulsion Allergy Vaccine Suppresses Alarmin Expression and Induces Bystander Suppression of Reactivity to Multiple Food Allergens.Front Immunol. 2021 Feb 25;12:599296. doi: 10.3389/fimmu.2021.599296. eCollection 2021. Front Immunol. 2021. PMID: 33717078 Free PMC article.
Claim: Peanut allergies are caused by the peanut oil in vaccines (Matt Roeske, 2024-07-22)
Evidence (2024-07-26): Misleading: Peanut allergies and peanut oil allergies aren’t one in the same. Some people with peanut allergies may safely consume peanut oil, particularly if it’s the highly-refined variety used in cooking and frying. While peanut oil was used as a vaccine adjuvant ingredient in a clinical trial for an influenza vaccine in the 1960s, this vaccine wasn't approved for public use. [...] The reel claimed that people are "having peanut allergies because they’ve been jabbed with peanut oil", drawing an implicit link between the alleged addition of peanut oil to certain vaccines in 1961 and a subsequent rise in peanut allergies since that time. [...] Peanut oil was only briefly tested as an adjuvant ingredient in vaccines in the 1960s. It was never approved as an ingredient for public use in vaccines and isn’t an ingredient in vaccines today. Further, there isn’t evidence to support that peanut oil causes peanut allergies; rather, risk for peanut allergy may instead be linked to factors like age, genetics, and other allergies.
Claim: Peanut allergies are caused by the peanut oil in vaccines (Matt Roeske, 2024-07-22)
Evidence (2017-02-16): Though articles and individuals attempting to make this link propose a variety of mechanisms for the ways in which an inoculation could contribute to the development of peanut allergies, each relies on the false premise that vaccines (childhood and/or influenza) contain undisclosed traces of peanut oil. [...] This assertion appears to have its roots in the 2011 book The Peanut Allergy Epidemic by Heather Fraser, which has a section about the potential presence of peanut oil adjuvants in vaccines. Fraser attempts to argue that some kinds of adjuvants in injections (not specifically childhood vaccines) may have, through poorly understood mechanisms, sensitized children to peanut and other allergies. This specific chapter (and the evidence it cites) appears to be the basis for a number peanut oil claims on numerous anti-vaccine websites. [...] In case the complete and total lack of evidence supporting the claim that peanut oil can be found in vaccines convinced you that they were peanut free, anti-vaccine advocates also throw in a burden-of-proof logical fallacy to contend with: that pharmaceutical companies are doing it secretly and there is literally no way to know for sure.
Claim: Peanut allergies are caused by the peanut oil in vaccines (Matt Roeske, 2024-07-22)
Evidence (2023-04-03): Peanut allergies affect 1 in 50 children, and the most severe cases lead to a potentially deadly immune reaction called anaphylactic shock.
Claim: Peanut allergies are caused by the peanut oil in vaccines (Matt Roeske, 2024-07-22)
Evidence (2014-11-01): Recent advances in immunotherapy and vaccine development for peanut allergy - PMID: 26288733 - PMCID: PMC4530404 - DOI: 10.1177/2051013615591739 [...] Peanut allergy is a common problem and can be the cause of severe, life-threatening allergic reactions. It rarely resolves, with the majority of patients carrying the disease onto adulthood. Peanut allergy poses a significant burden on the quality of life of sufferers and their families, which results mainly from the fear of accidental peanut ingestion, but is also due to dietary and social restrictions. Current standard management involves avoidance, patient education and provision of emergency medication, for use in allergic reactions, when they occur. Efforts have been made to develop a vaccine for peanut allergy. Recent developments have also highlighted the use of immunotherapy, which has shown promise as an active form of treatment and may present a disease-modifying therapy for peanut allergy. So far, results, especially from oral immunotherapy studies, have shown good efficacy in achieving desensitization to peanut with a good safety profile. However, the capacity to induce long-term tolerance has not been demonstrated conclusively yet and larger, phase III studies are required to further investigate safety and efficacy of this intervention. Peanut immunotherapy is not currently recommended for routine clinical use or outside specialist allergy units. [...] Oral Immunotherapy for Peanut Allergy.Annu Rev Med. 2016;67:375-85. doi: 10.1146/annurev-med-061014-094943. Epub 2015 Aug 26. Annu Rev Med. 2016. PMID: 26332004 Review.
Claim: Peanut allergies are caused by the peanut oil in vaccines (Matt Roeske, 2024-07-22)
Evidence (2023-11-01): Background: Allergy to peanut is one of the leading causes of anaphylactic reactions among food allergic patients. Immunization against peanut allergy with a safe and protective vaccine holds a promise to induce durable protection against anaphylaxis caused by exposure to peanut. A novel vaccine candidate (VLP Peanut), based on virus-like particles (VLPs), is described here for the treatment of peanut allergy. Methods and results: VLP Peanut consists of two proteins: a capsid subunit derived from Cucumber mosaic virus engineered with a universal T-cell epitope (CuMVTT ) and a CuMVTT subunit fused with peanut allergen Ara h 2 (CuMVTT -Ara h 2), forming mosaic VLPs. Immunizations with VLP Peanut in both naïve and peanut-sensitized mice resulted in a significant anti-Ara h 2 IgG response. Local and systemic protection induced by VLP Peanut were established in mouse models for peanut allergy following prophylactic, therapeutic, and passive immunizations. Inhibition of FcγRIIb function resulted in a loss of protection, confirming the crucial role of the receptor in conferring cross protection against peanut allergens other than Ara h 2. [...] Vaccine against peanut allergy based on engineered virus-like particles displaying single major peanut allergens.J Allergy Clin Immunol. 2020 Apr;145(4):1240-1253.e3. doi: 10.1016/j.jaci.2019.12.007. Epub 2019 Dec 19. J Allergy Clin Immunol. 2020. PMID: 31866435 -
Claim: Peanut allergies are caused by the peanut oil in vaccines (Matt Roeske, 2024-07-22)
Evidence (2021-05-09): The world is one step closer to a vaccine against peanut allergy after UK biotech Allergy Therapeutics announced plans to test its jab in human clinical trials.
Claim: Peanut allergies are caused by the peanut oil in vaccines (Matt Roeske, 2024-07-22)
Evidence (2020-04-28): Vaccine Ingredients: Corn and Peanut Oils "My daughter has a corn allergy, do I need to worry about her getting vaccines?" "I heard the rise in peanut allergies is because peanut oils are used in vaccines. Is this true?" Both of these questions are related to the notion that oils in vaccines can cause allergic reactions in those who have food sensitivities. Indeed, if someone has a sensitivity to a vaccine component, they may be advised not to get it; however, vaccines do not contain either corn or peanut oils.
Claim: Peanut allergies are caused by the peanut oil in vaccines (Matt Roeske, 2024-07-22)
Evidence (2006-02-23): 2. Peanut oil is used in vaccines in adjuvants or as a vaccine carrier. The ingredients of adjuvants or vaccine carriers are not listed individually on the package insert. So the physician would have no way of knowing that there was peanut oil in the vaccine. The ingredients of adjuvants is considered a "trade secret" and has the protection of many governments not to be revealed. [...] 11. How pure can we make peanut oil? I assume it is highly refined but it only would take a teeny weeny bit of peanut protein in a vaccine to create a problem. That is, of course, assuming that it is ONLY the peanut protein that causes the allergy. Using my "guessing" math, only 1 shot out of 1680 would need to be contaminated to create a peanut allergy in 1 in 70 people in Great Britain.
Claim: Peanut allergies are caused by the peanut oil in vaccines (Matt Roeske, 2024-07-22)
Evidence (2020-09-29): Vaccines don't cause food allergies. Here's what parents need to know about vaccines and food allergies. [...] The fact that vaccines don't cause food allergies has been proven by several well-controlled studies. [...] Even though vaccines don't cause food allergies, some people with existing food allergies still need to be cautious about certain vaccines. If a vaccine contains a food that they are already allergic to, it may cause them to develop an allergic reaction. They might even develop anaphylaxis, a severe allergic reaction that requires immediate emergency attention.
Claim: Peanut allergies are caused by the peanut oil in vaccines (Matt Roeske, 2024-07-22)
Evidence (2020-01-31): "Peanut allergy affects approximately 1 million children in the U.S. and only 1 out of 5 of these children will outgrow their allergy. Because there is no cure, allergic individuals must strictly avoid exposure to prevent severe and potentially life-threatening reactions," said Peter Marks, M.D., Ph.D., director of the FDA’s Center for Biologics Evaluation and Research. "Even with strict avoidance, inadvertent exposures can and do occur. When used in conjunction with peanut avoidance, Palforzia provides an FDA-approved treatment option to help reduce the risk of these allergic reactions in children with peanut allergy." Peanut allergy is a condition in which the body’s immune system mistakenly identifies even small amounts of peanut as harmful. Allergic reactions to peanut are unpredictable in occurrence and in how they present, with some individuals experiencing severe reactions from even trace amounts. Physical symptoms can develop within seconds of exposure and may include skin reactions (e.g., hives, redness or swelling), digestive discomfort, or more dangerous reactions, such as constriction of the throat and airways, and loss of adequate blood flow to vital organs of the body. Antihistamines and epinephrine can be used to treat allergic reactions, but severe reactions can be fatal even with appropriate, prompt treatment. Palforzia cannot be used for the emergency treatment of allergic reactions, including anaphylaxis.
Claim: Peanut allergies are caused by the peanut oil in vaccines (Matt Roeske, 2024-07-22)
Evidence (2024-02-19): No. Vaccines available in the United States do not contain peanut products.
Claim: Peanut allergies are caused by the peanut oil in vaccines (Matt Roeske, 2024-07-22)
Evidence (2019-12-06): Peanut allergies occur when the immune system mistakenly identifies peanuts as an allergen signalling immune cells to release chemicals resulting in adverse reactions that can range from mild hives, cramps, nausea and vomiting to life threatening anaphylactic reactions that require immediate medical attention. Severe allergic reactions can include impaired breathing, swelling in the throat, a sudden drop in blood pressure, dizziness, and even death. [...] The new peanut allergy vaccine is formulated by packaging bits of peanut proteins into the Sementis Copenhagen-vectored (SCV) virus platform. SCV is a ground-breaking technology developed by Dr Paul Howley, Chief Scientific Officer, Sementis and UniSA’s Professor John Hayball, Head of UniSA’s Experimental Therapeutics Laboratory. Prof Hayball says the peanut allergy vaccine tricks the immune system into seeing peanut allergens in a new light, so that the body responds normally instead of generating an allergic reaction.
Claim: Peanut allergies are caused by the peanut oil in vaccines (Matt Roeske, 2024-07-22)
Evidence (2020-05-04): Evidence that Food Proteins in Vaccines Cause the Development of Food Allergies and Its Implications for Vaccine Policy [...] Nobel Laureate Charles Richet demonstrated over a hundred years ago that injecting a protein into animals or humans causes immune system sensitization to that protein. Subsequent exposure to the protein can result in allergic reactions or anaphylaxis. This fact has since been demonstrated over and over again in humans and animal models. The Institute of Medicine (IOM) confirmed that food proteins in vaccines cause food allergy, in its 2011 report on vaccine adverse events. The IOM’s confirmation is the latest and most authoritative since Dr. Richet’s discovery. Many vaccines and injections contain food proteins. Many studies since 1940 have demonstrated that food proteins in vaccines cause sensitization in humans. Allergens in vaccines are not fully disclosed. No safe dosage level for injected allergens has been established. As a result, allergen quantities in vaccines and injections are not regulated. Allergen quantities in vaccine excipients are also not regulated. It has been demonstrated that a smaller quantity of allergen is needed to cause sensitization than elicitation. It is well recognized that many currently approved vaccines have enough allergen to cause anaphylaxis. Therefore, they contain more than enough allergen to cause sensitization. Children today have fewer childhood infectious diseases.
Claim: Peanut allergies are caused by the peanut oil in vaccines (Matt Roeske, 2024-07-22)
Evidence (2016-11-09): In the mid-1960s, peanut oils were first introduced into vaccines because scientists hypothesized they would "prolong" immunity. It was originally used as an adjuvant (a substance that enhances the body’s immune response to an antigen). It is a complete myth that the greater the allergic response to the vaccine, the greater the immunity is conferred. The dangers of its use are well-documented, but anyone who tests this myth is referred to as anti-science, anti-vaccine and a conspiracy theorist. There is no faster way for a doctor to lose their license to practice medicine than to challenge this commandment of vaccine mythology. If they started putting peanut oil in vaccines in the 1960s, then why did the peanut allergies experience a massive upsurge in number more recently? It all started when the mandated schedule of the number and frequency of vaccines for children under age 7 doubled, and then tripled. In 1980 children received on average 20 vaccines, in 1995 it was increased to around 40 vaccines, and by 2016 we are now at approximately 70 vaccines. [...] Wells, S. D. "Severe Childhood Allergies to Peanuts, Eggs and Dairy Directly Linked to ‘trace’ Ingredients in Common Vaccines." NaturalNews. N.p., 05 Oct. 2016. Web. 27 Oct. 2016.
Claim: Peanut allergies are caused by the peanut oil in vaccines (Matt Roeske, 2024-07-22)
Evidence (2024-07-26): Factually inaccurate: Peanut oil isn’t an ingredient in vaccines. Risk factors for peanut allergies are unclear, but are commonly linked to age, genetics, and history of other allergies—not consumption of peanut oil. [...] The reel claimed that people are "having peanut allergies because they’ve been jabbed with peanut oil", drawing an implicit link between the alleged addition of peanut oil to certain vaccines in 1961 and a subsequent rise in peanut allergies since that time. [...] Peanut oil was only briefly tested as an adjuvant ingredient in vaccines in the 1960s. It was never approved as an ingredient for public use in vaccines and isn’t an ingredient in vaccines today. Further, there isn’t evidence to support that peanut oil causes peanut allergies; rather, risk for peanut allergy may instead be linked to factors like age, genetics, and other allergies.
Claim: Peanut allergies are caused by the peanut oil in vaccines (Matt Roeske, 2024-07-22)
Evidence (2024-01-01): The big change came with vaccines. Peanut oils were introduced as vaccine excipients in the mid 1960s. An article appeared in the NY Times on 18 Sept, 1964 that would never be printed today. [8] The author described how a newly patented ingredient containing peanut oil was added as an adjuvant to a new flu vaccine, in order to prolong the "immunity." The oil was reported to act as a time release capsule, and theoretically enhanced the vaccine's strength. Same mechanism as with penicillin. [...] Why was peanut allergy so violent? Adjuvant pioneer Maurice Hilleman claimed peanut oil adjuvants had all protein removed by refining. [9] The FDA disagreed. They said some peanut protein traces would always persist [10]- that even the most refined peanut oils still contained some traces of intact peanut proteins. This was the reason doctors were directed to inject vaccines intramuscular rather than intravenous -- a greater chance of absorption of intact proteins, less chance of reaction. [...] So in addition to all the other problems with vaccines delineated in our text, now we have a new one -- peanut oil excipients. Which all by themselves can cause severe, even fatal, episodes of shock, as well as chronic allergy -- irrespective of the mercury, aluminum, formaldehyde, ethylene glycol, and the attenuated pathogens which the manufacturers do admit to.
Claim: Peanut allergies are caused by the peanut oil in vaccines (Matt Roeske, 2024-07-22)
Evidence (2019-12-01): Vaccine against peanut allergy based on engineered virus-like particles displaying single major peanut allergens - PMID: 31866435 - DOI: 10.1016/j.jaci.2019.12.007 Vaccine against peanut allergy based on engineered virus-like particles displaying single major peanut allergens [...] Results: The vaccines CuMVtt-Ara R, CuMVtt-Ara h 1, and CuMVtt-Ara h 2 protected peanut-sensitized mice against anaphylaxis after intravenous challenge with the whole peanut extract. Vaccines did not cause allergic reactions in sensitized mice. CuMVtt-Ara h 1 was able to induce specific IgG antibodies, diminished local reactions after skin prick tests, and reduced the infiltration of the gastrointestinal tract by eosinophils and mast cells after oral challenge with peanut. The ability of CuMVtt-Ara h 1 to protect against challenge with the whole extract was mediated by IgG, as shown via passive IgG transfer. FcγRIIb was required for protection, indicating that immune complexes with single allergens were able to block the allergic response against the whole extract, consisting of a complex allergen mixture.
Claim: “Would you take a vaccine with a 33% death rate to feel safe from a virus with a .06% death rate?” (Facebook users, 2020-08-15)
Evidence (2020-08-15): Inaccurate: The claim that a COVID-19 vaccine has a 33% death rate is not supported by scientific evidence. This claim is likely based on a separate false claim about a nonexistent COVID-19 vaccine trial from Ukraine.
Claim: “Would you take a vaccine with a 33% death rate to feel safe from a virus with a .06% death rate?” (Facebook users, 2020-08-15)
Evidence (2024-03-18): To understand how the pandemic is evolving, it’s crucial to know how death rates from COVID-19 are affected by vaccination status. The death rate is a key metric that can accurately show how effective vaccines are against severe forms of the disease. This may change over time when there are changes in the prevalence of COVID-19 and because of factors such as waning immunity, new strains of the virus, and the use of boosters. [...] Of 50 vaccinated people, 5 died → the death rate among the vaccinated is 10%. We, therefore, see that the death rate among the vaccinated is 5 times lower than among the unvaccinated.
Claim: “Would you take a vaccine with a 33% death rate to feel safe from a virus with a .06% death rate?” (Facebook users, 2020-08-15)
Evidence (2021-07-14): One of the best ways of guarding against new variants is to continue applying tried-and-tested public health measures and rolling out vaccines. All COVID-19 vaccines approved for emergency use listing by WHO have been thoroughly tested and proven to provide a high degree of protection against serious illness and death. As stronger virus variants emerge, it’s important to take your vaccine when it’s your turn.
Claim: “Would you take a vaccine with a 33% death rate to feel safe from a virus with a .06% death rate?” (Facebook users, 2020-08-15)
Evidence (2024-09-12): Yes, COVID-19 vaccines are safe for people who have existing health conditions, including conditions that have a higher risk of getting serious illness with COVID-19.
Claim: “Would you take a vaccine with a 33% death rate to feel safe from a virus with a .06% death rate?” (Facebook users, 2020-08-15)
Evidence (2023-11-06): COVID-19 vaccination reduces the risk of death from COVID-19. Social media posts have misused survey data and adverse events reports to falsely claim that COVID-19 vaccines have killed more people than COVID-19. But serious adverse events resulting from vaccination, including deaths, are rare. [...] Furthermore, both Kirsch’s and McCullough’s conclusions are inconsistent with the other available evidence on vaccine safety. "Deaths that are directly caused by a COVID vaccine, they are vanishingly rare," Schaffner said. [...] Before getting to the questions on deaths, readers were asked: "When did you first figure out that vaccines were not safe?" According to survey responses posted by Kirsch, only nine people out of more than 10,000 respondents selected the option: "Still think vaccines are safe."
Claim: “Would you take a vaccine with a 33% death rate to feel safe from a virus with a .06% death rate?” (Facebook users, 2020-08-15)
Evidence (2024-09-27): Yes. COVID-19 vaccines approved by the FDA meet rigorous testing criteria and are safe and effective at preventing serious illness, hospitalization and death. Millions of people have received the vaccines, and the CDC continues to monitor their safety and effectiveness as well as rare adverse events.
Claim: “Would you take a vaccine with a 33% death rate to feel safe from a virus with a .06% death rate?” (Facebook users, 2020-08-15)
Evidence (2021-06-25): Bladen County, which has a vaccination rate of only 33%, is experiencing critical viral spread and increases in COVID-19 cases and hospitalizations. Today’s COVID-19 County Alert System report shows the county is now red. State health officials urge people to get vaccinated now to protect themselves and the community from serious illness and virus-related hospitalization and death.