copenlu/druid huggingface dataset:
Claim: Any form of vaccination after COVID19 vaccination can be life threatening (Social Media Users, 2021-07-13)
Evidence (2022-11-01): Intervention: Any type of COVID-19 vaccine. We included the following types of COVID-19 vaccines: BNT162b2 ("Pfizer/BioNTech"), AZD1222 ("Oxford-AstraZeneca"), mRNA-1273 ("Moderna"), and Ad26.COV2.S ("Janssen"). Vaccine doses can be administered before or after SARS-CoV-2 acute infection. [...] The second topic is to know if COVID-19 vaccines represent a risk for those individuals with ongoing long-COVID symptomatology. We identified eleven level III studies of moderate to high methodological quality investigating the impact of vaccine on individuals who had previously suffered from COVID-19 and developed long-COVID (infection-long COVID-vaccine design). The results here were less consistent, since 63% of the studies (n=7/11) found that vaccination improved ongoing symptoms of long-COVID, whereas 36% (n=4/11) reported small changes or even worsening in some patients. Again, the definition of long-COVID among the studies was inconsistent. This heterogeneity in the response against vaccines of individuals with long-COVID could be related to the complexity of this condition. For instance, Tsuchida et al.24 identified that people experiencing a worsening of long-COVID symptoms after vaccination are those also showing excessive immune response to vaccination, with higher increased rate of antibody titers. On the contrary, Peghin et al.24 observed that COVID-19 vaccines did not produce an altered humoral response in individuals with current long-COVID. Discrepancies between these studies could be related to the fact that numerous autoantibodies may be produced after SARS-CoV-2 infection43 and, accordingly, COVID-19 vaccines effects could be dependent on the host immune response. [...] Symptoms after COVID-19 vaccination in patients with post-acute sequelae of SARS-CoV-2
Claim: Any form of vaccination after COVID19 vaccination can be life threatening (Social Media Users, 2021-07-13)
Evidence (2021-12-01): These findings suggest that some individuals experience more adverse effects after COVID-19 vaccination, but serious adverse effects are rare. [...] The objectives of this study were to describe adverse effects and identify factors associated with adverse effects after COVID-19 vaccination in participants in an online cohort study. In addition, the study sought to identify factors associated with more severe adverse effects. These results may help the public gain a greater understanding of the real-world experience of adverse effects after COVID-19 vaccination. [...] In this study, people with prior COVID-19 had greater odds of adverse effects and more severe adverse effects after COVID-19 vaccination. Data from randomized clinical trials were not conclusive with regard to the association between prior COVID-19 and adverse effects after vaccination.5 Other smaller real-world reports have also reported increased adverse effects in people with prior COVID-19.22 In this study, which included 895 participants with prior COVID-19, there was a strong association between prior COVID-19 and vaccine adverse effects.
Claim: Any form of vaccination after COVID19 vaccination can be life threatening (Social Media Users, 2021-07-13)
Evidence (2022-06-01): Conclusions The study provides reassuring data on low rates of AEs after COVID-19 vaccination. Differences in reactogenicity-type AE profiles between ChAdOx1 and BNT162b2 and between first and second doses of these vaccines were observed. [...] VAC4COVID (SARS-CoV-2 Vaccination for COVID-19 Disease Safety Study) is an independent academic UK-wide web-based study designed to collect patient-reported adverse medical events before and after vaccination. The study design also allows clinical validation of any serious or non-serious adverse events of special interest (AESIs).10 We present an interim analysis of AR data collected between 2 February 2021 and 5 October 2021 in the VAC4COVID study. [...] The two most commonly used COVID-19 vaccines in the UK, ChAdOx1 and BNT162b2, are well tolerated. The majority of vaccine recipients in this study reported no adverse health events after vaccination, and most reported events were of mild or moderate severity. Furthermore, a high proportion of participants reported subjective improvements in overall health and well-being after vaccination. These data should be reassuring to people contemplating vaccination. However, there are differences between the reactogenicity-related symptom profiles of the vaccines that should be considered in planning future vaccination programmes. The ongoing VAC4COVID remote active surveillance system is designed to monitor vaccine safety and effectiveness by combining participant-reported data with linked health and administrative data; the flexible design would allow data collection in any country for which there is a suitable translated MedDRA dictionary. As well as providing comparative COVID-19 vaccine AE data, the system may also be adapted to monitor new non-COVID vaccines and other medications.
Claim: Any form of vaccination after COVID19 vaccination can be life threatening (Social Media Users, 2021-07-13)
Evidence (2024-10-03): Study reveals lower cardiovascular risks after COVID-19 vaccination, despite increased myocarditis and pericarditis in younger males. [...] Existing evidence does not indicate that COVID-19 vaccination increases the risk of MI, whereas the risk of atrial fibrillation (AF) is extremely low. Furthermore, individual-level data has not suggested an increased risk of stroke after vaccination. [...] The current study reports reduced risks of several serious cardiovascular outcomes following COVID-19 vaccination in a cohort of Swedish individuals, which could be attributed to protection conferred by the vaccine against severe disease. Nevertheless, an increased risk of extrasystoles, TIA, myocarditis, and pericarditis was observed after COVID-19 mRNA vaccination.
Claim: Any form of vaccination after COVID19 vaccination can be life threatening (Social Media Users, 2021-07-13)
Evidence (2023-12-05): Yes, all WHO emergency-use listed or prequalified COVID-19 vaccines provide protection against severe disease and death from circulating COVID-19 variants. Any of the approved COVID-19 vaccines can be used either for the initial series or revaccination. [...] People who get COVID-19 after being vaccinated are much more likely to only experience mild symptoms as effectiveness against serious illness and death remains high. Vaccine effectiveness wanes over time, so it’s important to stay updated with your shots as recommended by your health care provider. [...] Like with any vaccine, some people will experience mild to moderate side effects after being vaccinated against COVID-19. This is a normal sign that the body is developing protection.
Claim: Any form of vaccination after COVID19 vaccination can be life threatening (Social Media Users, 2021-07-13)
Evidence (2024-09-30): Background and aims: While the rationale for coronavirus disease 2019 (COVID-19) vaccination is to reduce complications and overall mortality, some cardiovascular complications from the vaccine itself have been demonstrated. Myocarditis and pericarditis are recognized as rare acute adverse events after mRNA vaccines in young males, while evidence regarding other cardiovascular events remains limited and inconsistent. This study assessed the risks of several cardiovascular and cerebrovascular events in a Swedish nationwide register-based cohort. [...] Results: For most studied outcomes, decreased risks of cardiovascular events post-vaccination were observed, especially after dose three (HRs for dose three ranging from .69 to .81), while replicating the increased risk of myocarditis and pericarditis 1-2 weeks after COVID-19 mRNA vaccination. Slightly increased risks, similar across vaccines, were observed for extrasystoles [HR 1.17 (95% CI 1.06-1.28) for dose one and HR 1.22 (95% CI 1.10-1.36) for dose two, stronger in elderly and males] but not for arrhythmias and for transient ischaemic attack [HR 1.13 (95% CI 1.05-1.23), mainly in elderly] but not for stroke. Conclusions: Risk of myopericarditis (mRNA vaccines only), extrasystoles, and transient ischaemic attack was transiently increased after COVID-19 vaccination, but full vaccination substantially reduced the risk of several more severe COVID-19-associated cardiovascular outcomes, underscoring the protective benefits of complete vaccination.
Claim: Any form of vaccination after COVID19 vaccination can be life threatening (Social Media Users, 2021-07-13)
Evidence (2022-02-26): Risk of infection, hospitalisation, and death up to 9 months after a second dose of COVID-19 vaccine: a retrospective, total population cohort study in Sweden aDepartment of Community Medicine and Rehabilitation, Unit of Geriatric Medicine, Umeå University, Umeå, Sweden bDepartment of Public Health and Clinical Medicine, Section of Sustainable Health, Umeå University, Umeå, Sweden cSchool of Sport Sciences, UiT the Arctic University of Norway, Tromsø, Norway [...] The different results in recent studies might relate to several factors, such as the evaluations of vaccines that might have different long-lasting effects,16,18–20 different age of the participants,18 varying and relatively short follow-up times,15,16,22 different patterns of risk compensation in the populations, different severities and definitions of infections included as outcomes, and variations in infection pressure and variant exposure during follow-up. Collectively, vaccine effectiveness beyond 6 months remains incompletely understood. In this study, we investigated the effectiveness of COVID-19 vaccination against the risk of infection, hospitalisation, and death during the first 9 months after vaccination for the total population of Sweden.
Claim: Any form of vaccination after COVID19 vaccination can be life threatening (Social Media Users, 2021-07-13)
Evidence (2023-05-01): Protection of COVID-19 vaccination and previous infection against omicron BA.1, BA.2 and delta SARS-CoV-2 infections [...] Association of COVID-19 vaccination with symptomatic SARS-CoV-2 infection by time since vaccination and delta variant predominance [...] Protection against SARS-CoV-2 after COVID-19 vaccination and previous infection
Claim: Any form of vaccination after COVID19 vaccination can be life threatening (Social Media Users, 2021-07-13)
Evidence (2024-08-05): Key Points - Anaphylaxis, an acute and potentially life-threatening allergic reaction, has been reported rarely following COVID-19 vaccination. [...] Anaphylaxis, an acute and potentially life-threatening allergic reaction, has been reported rarely following COVID-19 vaccination. These interim considerations provide recommendations on assessment and potential management of anaphylaxis following COVID-19 vaccination. Detailed information on CDC recommendations for vaccination, including contraindications and precautions to vaccination, can be found in the Interim Clinical Considerations for Use of COVID-19 Vaccines in the United States. Patients should be screened prior to receipt of each vaccine dose, and those with a contraindication should not be vaccinated. Resources from Immunize.org are available to help providers determine if a contraindication or precaution exists for all routinely recommended vaccines for adults and children and teens, including COVID-19 vaccines. [...] Anyone can report any adverse events, including anaphylaxis, that occur in a recipient following COVID-19 vaccination, to the Vaccine Adverse Event Reporting System (VAERS). Reporting is encouraged for any clinically significant adverse event, even if it is uncertain whether the vaccine caused the event. For detailed reporting requirements for VAERS, please see Clinical Guidance for COVID-19 Vaccination | CDC. Refer to the VAERS website or call 1-800-822-7967 for more information on how to submit a report to VAERS.
Claim: Any form of vaccination after COVID19 vaccination can be life threatening (Social Media Users, 2021-07-13)
Evidence (2023-05-17): Concern has continued to grow over a small, but growing number of cases of a rare, but serious blood clotting disorders associated with the Johnson & Johnson coronavirus vaccine. In May, the Food and Drug Administration (FDA) put new restrictions on who can get the J&J vaccine, based on a fresh review of data on the life-threatening blood clots that have been associated with the vaccine. This was five months after the Centers for Disease Control and Prevention (CDC) endorsed a decision to give a preferential recommendation to the Pfizer-BioNTech and Moderna vaccines. [...] The Pfizer-BioNTech and Moderna COVID-19 vaccines, both of which are mRNA vaccines and use a different method to protect against the virus, have not been linked to blood clots at this time. [...] While the risk for a rare blood clot is low, anyone who still gets the Johnson & Johnson vaccine should know about early symptoms of the disorder. The CDC recommends seeking immediate medical care if you develop any of the following symptoms after getting the shot, especially if you are a woman aged 50 or younger:
Claim: Any form of vaccination after COVID19 vaccination can be life threatening (Social Media Users, 2021-07-13)
Evidence (2021-03-16): Following implementation of vaccination, cases of anaphylaxis after administration of the Pfizer-BioNTech and Moderna vaccines began to be reported.3,4 Anaphylaxis is a life-threatening allergic reaction that can occur after vaccination, with onset typically within minutes to hours.5 The initial estimated reporting rates for anaphylaxis in the US were 11.1 cases per million doses administered of the Pfizer-BioNTech vaccine (December 14-23, 2020) and 2.5 cases per million doses administered of the Moderna vaccine (December 21, 2020-January 10, 2021).3,4 Since these early estimates were generated, millions more doses of both vaccines have been administered and safety monitoring has detected additional cases of anaphylaxis. This analysis updates the reporting rates of anaphylaxis in individuals following receipt of either the Pfizer-BioNTech or Moderna vaccine. [...] Continued safety monitoring of mRNA COVID-19 vaccines in the US has confirmed that anaphylaxis following vaccination is a rare event, with rates of 4.7 cases/million Pfizer-BioNTech vaccine doses administered and 2.5 cases/million Moderna vaccine doses administered, based on information through January 18, 2021. When considered in the context of morbidity and mortality from COVID-19,9 the benefits of vaccination far outweigh the risk of anaphylaxis, which is treatable. Because of the acute, life-threatening nature of anaphylaxis, immediate epinephrine administration is indicated for all cases. CDC guidance on use of mRNA COVID-19 vaccines8 and management of anaphylaxis is available.10 All facilities administering COVID-19 vaccines should have the necessary supplies and trained medical personnel available to manage anaphylaxis. [...] N. Allergic reactions including anaphylaxis after receipt of the first dose of Pfizer-BioNTech COVID-19 vaccine.
Claim: Any form of vaccination after COVID19 vaccination can be life threatening (Social Media Users, 2021-07-13)
Evidence (2024-10-02): For claims associated with the COVID-19 vaccine or other COVID-19 related countermeasures, please file your Request for Benefits with the Countermeasures Injury Compensation Program. Vaccines save lives by preventing disease. Most people who get vaccines have no serious problems. Vaccines, like any medicines, can cause side effects, but most are very rare and very mild. Some health problems that follow vaccinations are not caused by vaccines.
Claim: Any form of vaccination after COVID19 vaccination can be life threatening (Social Media Users, 2021-07-13)
Evidence (2024-10-02): Your SMART Health Card will only contain COVID-19 vaccinations that have been entered into the Arkansas immunization information system, WebIZ. If you believe there are COVID-19 vaccinations missing from your COVID-19 SMART Health Card, you may reach out to the site where you received the vaccination to have it added to the WebIZ system. If you received COVID-19 vaccinations in another state, you may provide your vaccination information to your health care provider for a local health unit and the information will be added to your Arkansas WebIZ record. The COVID-19 SMART Health Care QR Code is not connected to the WebIZ. Each time you receive an additional dose of COVID-19 vaccine, you will need to obtain a new COVID-19 SMART Health Card to ensure all vaccinations are included on your card and in your QR code. [...] Vaccines are the safest way to protect you, your children, and your community from a long list of serious and potentially life-threatening illnesses. Vaccine-preventable diseases can be very serious, may require hospitalization, or even be deadly – especially in infants and young children.
Claim: Any form of vaccination after COVID19 vaccination can be life threatening (Social Media Users, 2021-07-13)
Evidence (2023-06-22): As with all medicines, COVID-19 vaccines have side effects, but these are far outweighed by the benefits in terms of protection against severe disease and death. [...] Events of hypersensitivity and anaphylaxis have been reported following COVID-19 vaccination. [...] Very rare events of TTS may occur after vaccination with COVID-19 vaccines Vaxzevria (previously COVID-19 Vaccine AstraZeneca) and Jcovden (previously COVID-19 Vaccine Janssen).
Claim: Any form of vaccination after COVID19 vaccination can be life threatening (Social Media Users, 2021-07-13)
Evidence (2022-07-05): - COVID-19 vaccines lower the risk of life-threatening heart problems and other serious health issues. [...] It’s important to remember that any vaccine can cause side effects. These are normal signs that your body is making protective antibodies. Side effects of COVID-19 vaccination are generally mild — discomfort at the injection site, fatigue, and muscle aches — and go away in a few days. Many people have no side effects at all. Serious side effects are very uncommon. Myocarditis has been linked with other vaccines, such as those that prevent influenza (flu), smallpox, and shingles.6 [...] Only about 1 out of 100 cases of heart inflammation linked with COVID-19 vaccines is life-threatening.5 An analysis of 627 cases of vaccine-linked myocarditis worldwide showed that 626 fully recovered — and one fatality.7
Claim: Any form of vaccination after COVID19 vaccination can be life threatening (Social Media Users, 2021-07-13)
Evidence (2024-10-03): COVID-19 vaccination is an important part of protecting yourself if you're at increased risk of getting seriously ill from COVID-19. [...] You may still get or spread COVID-19 even if you have a vaccine, so it's important to follow advice about how to avoid catching and spreading COVID-19. [...] There have been rare cases of inflammation of the heart (myocarditis) reported after COVID-19 vaccination. Most people who had this recovered following rest and simple treatments.
Claim: Any form of vaccination after COVID19 vaccination can be life threatening (Social Media Users, 2021-07-13)
Evidence (2024-01-01): Mild-to-moderate constitutional symptoms such as fever, fatigue, headache, or muscle aches are common in the first 24 to 48 hours following vaccination and are not suggestive of VITT. Patients with severe, recurrent, or persistent symptoms from 4 to 42 days following COVID-19 vaccination, including intense headache, abdominal pain, back pain, nausea and vomiting, vision changes, change in mental status, shortness of breath, leg pain and swelling, and/or bleeding/petechiae, should be evaluated urgently by a medical provider, and consideration given to underlying VITT. The peak time period for initial symptoms is days 6 to 14. [...] - See I et al. US Case Reports of Cerebral Venous Sinus Thrombosis With Thrombocytopenia After Ad26.COV2.S Vaccination, March 2 to April 21, 2021. JAMA. 2021 Jun 22;325(24):2448-2456. doi: 10.1001/jama.2021.7517. PMID: 33929487; PMCID: PMC8087975. [...] - Schultz NH et al. Thrombosis and thrombocytopenia after ChAdOx1 nCoV-19 vaccination. DOI: 10.1056/NEJMoa2104882.
Claim: Any form of vaccination after COVID19 vaccination can be life threatening (Social Media Users, 2021-07-13)
Evidence (2020-11-20): Post-authorization vaccine safety monitoring is a federal government responsibility shared primarily by FDA and the U.S. Centers for Disease Control and Prevention (CDC), along with other agencies involved in healthcare delivery. Post-authorization safety monitoring during the COVID-19 pandemic vaccination program will aim to continuously monitor the safety of COVID-19 vaccines to rapidly detect safety problems if they exist. There will be multiple, complementary systems in place with validated analytic methods that can rapidly detect signals for possible vaccine safety problems. The U.S. government has a well-established post-authorization/post-approval vaccine safety monitoring infrastructure that will be scaled up to meet the needs of a large-scale COVID-19 vaccination program. The U.S. government – in partnership with health systems, academic centers, and private sector partners – will use multiple existing vaccine safety monitoring systems to monitor COVID-19 vaccines in the post-authorization/approval period. Some of these systems are the Vaccine Adverse Event Reporting System (VAERS), the Vaccine Safety Datalink (VSD), the Biologics Effectiveness and Safety (BEST) Initiative, and Medicare claims data.
Claim: Any form of vaccination after COVID19 vaccination can be life threatening (Social Media Users, 2021-07-13)
Evidence (2024-08-08): In rare cases, people have experienced serious health events after COVID-19 vaccination. An adverse event (any side effect or health problem after vaccination that is concerning to you, even if you are not sure if the vaccine caused the event) can be caused by the vaccine or be a coincidental event that is not related to the vaccine, such as an unrelated fever, that happened following vaccination. [...] To date, the systems in place to monitor the safety of these vaccines have found two serious types of adverse events following COVID-19 vaccination. The two serious adverse events following COVID-19 vaccination currently used in the United States are anaphylaxis and myocarditis or pericarditis. [...] Multiple factors contribute to reports of death after COVID-19 vaccination, including heightened public awareness of COVID-19 vaccines, requirements under FDA authorization for COVID-19 vaccines that healthcare providers report any death after COVID-19 vaccination to VAERS (even if it is unclear whether the vaccine was the cause), and reporting requirements in CDC vaccine provider agreements. People receiving COVID-19 vaccines are less likely to die from COVID-19 and its complications and are at no greater risk of death from non-COVID causes, than unvaccinated people.27282930
Claim: Any form of vaccination after COVID19 vaccination can be life threatening (Social Media Users, 2021-07-13)
Evidence (2024-08-22): - Has had an allergic reaction after a previous dose of COVID-19 vaccine or an ingredient in the COVID-19 vaccine, or has any severe, life-threatening allergies - Has had myocarditis (inflammation of the heart muscle) or pericarditis (inflammation of the lining outside of the heart) [...] - Myocarditis (inflammation of the heart muscle) or pericarditis (inflammation of the lining outside the heart) have been seen rarely after COVID-19 vaccination. This risk has been observed most commonly in males 12 through 39 years of age. The chance of this occurring is low. [...] Seek medical attention right away if the vaccinated person experiences chest pain, shortness of breath, or feelings of having a fast-beating, fluttering, or pounding heart after COVID-19 vaccination. These could be symptoms of myocarditis or pericarditis.