copenlu/druid huggingface dataset:
Claim: Unapproved genetically modified organisms in the COVID-19 mRNA vaccines could permanently change our DNA (Julian Fidge, Rebekah Barnett, 2023-07-27)
Evidence (2021-06-02): RNA vaccines 2020 has witnessed unprecedented situations due to coronavirus pandemic that affected all aspects of life. The whole globe lived months of uncertainty before two companies have announced the incredible results of phase III clinical trials for two different mRNA-based vaccines. [...] Having said that, both mRNA-based vaccines represent a unique case that is considered one of the most advanced and promising achievements in the field of pharmaceutical biotechnology and biopharmaceutical formulations. More than three decades of research effort on developing gene therapy solutions for many diseases could not convey many healthcare policymakers, pharmaceutical companies, funding agencies, medicine agencies, and drug administrations to adopt gene therapy avenues as highly potential approaches to transfer the therapeutic strategies into a new era. However, these mRNA vaccines, which have been developed and approved within a few months, signify a breakthrough in the field of gene therapy, which has battled to achieve ordinary acknowledgement due to a large number of sceptical and conservative scientists and other claimed safety and translational concerns. Although these two vaccines are not the first approved drugs utilising genetic materials as active ingredients, they are believed to be a milestone in modern medical history that may forever change pharmaceutical approaches. [...] Unlike other vaccines, mRNA vaccines are flexible and adaptable; they can be modified to suit different emergent variants in a very short time with minimum effort. The lipid carriers can be used for the coming vaccines with changes in the mRNA sequence only. mRNA sequencing is not a complicated process and can be performed within weeks, according to Ugur Shahin, the CEO and co-founder of BioNtech.
Claim: Unapproved genetically modified organisms in the COVID-19 mRNA vaccines could permanently change our DNA (Julian Fidge, Rebekah Barnett, 2023-07-27)
Evidence (2022-05-01): mRNA isn’t the same as DNA, and it can’t combine with our DNA to change our genetic code. [...] Some viruses like HIV can integrate their genetic material into the DNA of their hosts, but this isn’t true of all viruses, and HIV can only do so with the help of specialised enzymes that it carries with it. MRNA vaccines don’t carry these enzymes, so there is no risk of the genetic material they contain altering our DNA. [...] So, although mRNA vaccines are a new technology, there is no reason to think that they will have a lasting effect on our biology – besides training our immune systems to prevent COVID-19 disease, that is.
Claim: Unapproved genetically modified organisms in the COVID-19 mRNA vaccines could permanently change our DNA (Julian Fidge, Rebekah Barnett, 2023-07-27)
Evidence (2020-08-17): A Facebook post shared thousands of times has claimed that "the new vaccine for Covid-19 will be the first of its kind EVER. It will be an mRNA vaccine which will literally alter your DNA. It will wrap itself into your system. You will essentially become a genetically modified human being." [...] It’s also true that mRNA vaccines are very novel, and if one were to be approved for human use for Covid-19, it would be the first of its kind. [...] It doesn’t change the body’s DNA or "wrap" itself. mRNA vaccines are generally viewed positively as they are cheap, and don’t involve using part of a virus-like some traditional vaccines.
Claim: Unapproved genetically modified organisms in the COVID-19 mRNA vaccines could permanently change our DNA (Julian Fidge, Rebekah Barnett, 2023-07-27)
Evidence (2023-10-03): NEWS EXPLAINER 03 October 2023 mRNA COVID vaccines saved lives and won a Nobel — what’s next for the technology? [...] Pioneers of mRNA COVID vaccines win medicine Nobel [...] How COVID unlocked the power of RNA vaccines
Claim: Unapproved genetically modified organisms in the COVID-19 mRNA vaccines could permanently change our DNA (Julian Fidge, Rebekah Barnett, 2023-07-27)
Evidence (2021-06-25): Both the Pfizer and Moderna vaccines are mRNA vaccines, which contain tiny fragments of the genetic material known as "messenger ribonucleic acid". And if social media is anything to go by, some people are concerned these vaccines can affect their genetic code. [...] Your genetic code is made up of a different, but related, molecule to the vaccine mRNA, known as DNA, or deoxyribonucleic acid. And mRNA can’t insert itself into your DNA for two reasons. [...] But GMOs are different to the mRNA technology used to make COVID vaccines. Unlike GMOs, which are produced by inserting DNA into the genome, vaccine mRNA will not be in our genes or passed to the next generation. It’s broken down very quickly.
Claim: Unapproved genetically modified organisms in the COVID-19 mRNA vaccines could permanently change our DNA (Julian Fidge, Rebekah Barnett, 2023-07-27)
Evidence (2023-11-17): There are no genetically modified organisms in the COVID-19 mRNA vaccines; no evidence these vaccines modify our DNA [...] In November 2023, Gentry Gevers, host of the Break Away USA podcast, posted a screenshot of a tweet by journalist Rebekah Barnett on Instagram that read "Australian GP sues Pfizer and Moderna over unapproved GMOs in mRNA Covid vaccines". It also claimed "the human genome could already be permanently altered". [...] COVID-19 mRNA vaccines don’t contain organisms. As such, the claim that they contain "unapproved GMOs" is inaccurate. One example of a COVID-19 vaccine that does contain a GMO and is regulated as such is the AstraZeneca-Oxford COVID-19 vaccine, as it uses a modified adenovirus vector to deliver the genetic material of the spike protein into cells.
Claim: Unapproved genetically modified organisms in the COVID-19 mRNA vaccines could permanently change our DNA (Julian Fidge, Rebekah Barnett, 2023-07-27)
Evidence (2024-01-03): The Surgeon General outlined concerns regarding nucleic acid contaminants in the approved Pfizer and Moderna COVID-19 mRNA vaccines, particularly in the presence of lipid nanoparticle complexes, and Simian Virus 40 (SV40) promoter/enhancer DNA. Lipid nanoparticles are an efficient vehicle for delivery of the mRNA in the COVID-19 vaccines into human cells and may therefore be an equally efficient vehicle for delivering contaminant DNA into human cells. The presence of SV40 promoter/enhancer DNA may also pose a unique and heightened risk of DNA integration into human cells. [...] On December 14, 2023, the FDA provided a written response providing no evidence that DNA integration assessments have been conducted to address risks outlined by the FDA themselves in 2007. Based on the FDA’s recognition of unique risks posed by DNA integration, the efficacy of the COVID-19 mRNA vaccine’s lipid nanoparticle delivery system, and the presence of DNA fragments in these vaccines, it is essential to human health to assess the risks of contaminant DNA integration into human DNA. The FDA has provided no evidence that these risks have been assessed to ensure safety. As such, Florida State Surgeon General Dr. Joseph A. Ladapo has released the following statement: [...] DNA integration poses a unique and elevated risk to human health and to the integrity of the human genome, including the risk that DNA integrated into sperm or egg gametes could be passed onto offspring of mRNA COVID-19 vaccine recipients. If the risks of DNA integration have not been assessed for mRNA COVID-19 vaccines, these vaccines are not appropriate for use in human beings.
Claim: Unapproved genetically modified organisms in the COVID-19 mRNA vaccines could permanently change our DNA (Julian Fidge, Rebekah Barnett, 2023-07-27)
Evidence (2023-04-18): No signs of DNA mutation or COVID-19 vaccine-induced cancer have been reported to date for the Pfizer-BioNTech COVID-19 vaccine. This refutes claims made on September 12, 2023 during a Pandemic Preparedness Listening Session hosted by the Senate Medical Affairs. During the session, the Committee heard remarks pertaining to the Pfizer-BioNTech messenger RNA (mRNA) COVID-19 vaccine, incorrectly stating that the vaccine could potentially impact a person’s DNA and be a theoretical cancer risk. There is no evidence to support these claims. [...] - Does an mRNA vaccine change your DNA? No, mRNA vaccines do not alter your DNA. In fact, they don’t interact directly with your DNA at all.9 - Did the FDA unauthorize the Pfizer-BioNTech COVID-19 vaccine?
Claim: Unapproved genetically modified organisms in the COVID-19 mRNA vaccines could permanently change our DNA (Julian Fidge, Rebekah Barnett, 2023-07-27)
Evidence (2022-04-14): Nucleic acid-based vaccines have shown remarkable potential, as manifested by recent FDA approval for emergency use of two mRNA vaccines (BNT162b2 by Pfizer/BioNTech and mRNA-1273 by Moderna) for combating the COVID-19 pandemic. Their impressive efficacy can be largely attributed to the successful LNP delivery platforms, which are used extensively for the delivery of other mRNA vaccines176,177. For example, saRNA encoding the SARS-CoV-2 spike protein encapsulated in LNPs achieved high and dose-dependent SARS-CoV-2-specific antibody titres in mouse sera, leading to neutralization of pseudotyped and wild-type virus14. The potency of mRNA vaccines could be boosted by nanoparticle-mediated co-delivery of immunostimulatory adjuvants178. Recently, lipid adjuvant-assisted mRNA vaccines were developed by high-throughput screening of ionizable or cationic lipids, which can simultaneously mediate mRNA delivery and provide adjuvant stimulation via the STING pathway or Toll-like receptor 4 pathway179. Beyond LNPs, polymeric nanoparticles and some inorganic nanoparticles have also been adopted to deliver nucleic acids for vaccination (Fig. 6c).
Claim: Unapproved genetically modified organisms in the COVID-19 mRNA vaccines could permanently change our DNA (Julian Fidge, Rebekah Barnett, 2023-07-27)
Evidence (2023-08-14): Officials have maintained that mRNA COVID vaccines do not alter our DNA, but a new case filed in the Federal Court of Australia raises difficult questions about how reliable this assurance is. Can COVID-19 vaccines alter my DNA? This question is posed on the Australian Government’s fact page about COVID vaccines. "No, COVID-19 vaccines do not alter your DNA," states the government advice. "DNA is stored in the protected centre of our cells – the nucleus. The mRNA is broken down quickly by the body. It never enters the nucleus, and cannot affect or combine with our DNA in any way to change our genetic code." [...] However, the TGA maintains that allegations put forward in the case about the potential for mRNA vaccines to alter the recipient’s DNA are unfounded. A spokesperson for the TGA told Umbrella News, "COVID-19 vaccines do not alter a person’s DNA. The mRNA in the vaccines does not enter the nucleus of cells and is not integrated into the human genome. Thus, the mRNA does not cause genetic damage or affect the offspring of vaccinated individuals."
Claim: Unapproved genetically modified organisms in the COVID-19 mRNA vaccines could permanently change our DNA (Julian Fidge, Rebekah Barnett, 2023-07-27)
Evidence (2024-09-01): Their main objective was to change the legislation’s definition of ‘gene therapy’. At present, mRNA vaccines (like the COVID-19 vaccine) are to be classified as gene therapy. However, they felt that only products that modified the genome should be classified as gene therapy. - 1.Do EMA and the Commission classify Comirnaty and Spikevax mRNA vaccines as gene therapy? If so, what are the corresponding regulatory consequences? [...] - [2] https://www.floridahealth.gov/_documents/newsroom/press-releases/2024/01/20240103-halt-use-covid19-mrna-vaccines.pr.pdf, 3 January 2024: ‘The FDA’s response does not provide data or evidence that the DNA integration assessments they recommended themselves have been performed.’ ‘DNA integration could theoretically [...] transform a healthy cell into a cancerous cell.’DNA fragments detected in monovalent and bivalent Pfizer/BioNTech and Moderna modRNA COVID-19 vaccines from Ontario, Canada:Exploratory dose response relationship with serious adverse events,David J. Speicher, Jessica Rose, L. Maria Gutschi, David Wiseman, Kevin McKernan, http://tinyurl.com/2s3npu8m: ‘All products tested exceeded the guidelines for residual DNA set by the FDA and WHO of 10 ng/dose by 188 –509-fold.’
Claim: Unapproved genetically modified organisms in the COVID-19 mRNA vaccines could permanently change our DNA (Julian Fidge, Rebekah Barnett, 2023-07-27)
Evidence (2021-07-13): AP’S ASSESSMENT: False. The posts misrepresent the court ruling. Humans cannot be patented, regardless of whether they are vaccinated or unvaccinated. COVID-19 vaccines do not alter people’s DNA. THE FACTS: An Instagram post circulating online falsely claims that mRNA vaccines against COVID-19 alter DNA, allowing humans to be patented and have their rights taken away. But COVID-19 vaccines, including those made by Pfizer and Moderna that rely on mRNA technology, do not change a person’s genetic makeup.
Claim: Unapproved genetically modified organisms in the COVID-19 mRNA vaccines could permanently change our DNA (Julian Fidge, Rebekah Barnett, 2023-07-27)
Evidence (2024-09-12): Both the Pfizer-BioNTech and the Moderna COVID-19 vaccines use genetically engineered messenger RNA (mRNA). The mRNA in the vaccine tells your cells how to make a harmless piece of virus that causes COVID-19. After you get an mRNA COVID-19 vaccine, your muscle cells begin making the protein pieces and displaying them on cell surfaces. The immune system recognizes the protein and begins building an immune response and making antibodies. After delivering instructions, the mRNA is immediately broken down. It never enters the nucleus of your cells, where your DNA is kept. [...] - FDA approves and authorizes updated mRNA COVID-19 vaccines to better protect against currently circulating variants. U.S. Food and Drug Administration. https://www.fda.gov/news-events/press-announcements/fda-approves-and-authorizes-updated-mrna-covid-19-vaccines-better-protect-against-currently. Accessed Aug. 22, 2024.
Claim: Unapproved genetically modified organisms in the COVID-19 mRNA vaccines could permanently change our DNA (Julian Fidge, Rebekah Barnett, 2023-07-27)
Evidence (2022-02-01): Both the DNA and RNA vaccines can produce B and T cell-mediated immunity, though they have different conveniences. DNA vaccines have a risk of integrating the DNA with host DNA, whereas RNA vaccines have no such type of risk. Moreover, RNA vaccines require more cold storage temperature than DNA vaccines [55]. There are ten COVID-19 vaccine candidates in the clinical, and 11 candidates are in the preclinical evaluation stage as of 13 August 2021, which are developed using the DNA platform [83]. On the other hand, three COVID-19 vaccine candidates have been employed as an emergency vaccine, and 34 more vaccine candidates in the clinical and preclinical evaluation stage developed using the RNA platform [84]. BNT162b2 (97 countries), mRNA-1273 (65 countries), and TAK-919 (Japan) are mRNA based vaccines that have been using worldwide as authorized vaccines for COVID-19 [34]. [...] Lamb YN. BNT162b2 mRNA COVID-19 vaccine: first approval. Drugs. 2021;81:495–501. https://doi.org/10.1007/s40265-021-01480-7.
Claim: Unapproved genetically modified organisms in the COVID-19 mRNA vaccines could permanently change our DNA (Julian Fidge, Rebekah Barnett, 2023-07-27)
Evidence (2024-09-17): COVID-19 vaccines do not alter DNA. Both messenger RNA (mRNA) and protein subunit COVID-19 vaccines work by delivering instructions (genetic material) to your cells to start building protection against the virus that causes COVID-19. [...] The genetic material delivered by mRNA vaccines never enters the nucleus of your cells, which is where your DNA is kept, so the vaccine does not alter your DNA.
Claim: Unapproved genetically modified organisms in the COVID-19 mRNA vaccines could permanently change our DNA (Julian Fidge, Rebekah Barnett, 2023-07-27)
Evidence (2017-11-22): The mRNA used in COVID-19 vaccines does not interfere with our genetic code. This is because: [...] COVID-19 mRNA vaccines can sometimes contain truncated (shorter) or modified mRNA molecules. These are considered impurities and are not expected to affect safety or efficacy. [...] mRNA vaccines are not genetically modified organisms (GMOs) either because they do not contain or consist of an organism.
Claim: Unapproved genetically modified organisms in the COVID-19 mRNA vaccines could permanently change our DNA (Julian Fidge, Rebekah Barnett, 2023-07-27)
Evidence (2024-07-10): FDA Approves and Authorizes Updated mRNA COVID-19 Vaccines to Better Protect Against Currently Circulating Variants Today, the U.S. Food and Drug Administration approved and granted emergency use authorization (EUA) for updated mRNA COVID-19 vaccines (2024-2025 formula) to include a monovalent (single) component that corresponds to the Omicron variant KP.2 strain of SARS-CoV-2. [...] FDA Takes Action on Updated mRNA COVID-19 Vaccines to Better Protect Against Currently Circulating Variants
Claim: Unapproved genetically modified organisms in the COVID-19 mRNA vaccines could permanently change our DNA (Julian Fidge, Rebekah Barnett, 2023-07-27)
Evidence (2024-04-03): You asked, we answered: Can mRNA vaccines alter human DNA? [...] No, the vaccines cannot change your DNA. [...] Additionally, DNA is stored in the nucleus of your cells. mRNA vaccines are designed to do their work outside of the nucleus and have not been observed to interact with the nucleus. Learn more about how mRNA vaccines work.
Claim: Unapproved genetically modified organisms in the COVID-19 mRNA vaccines could permanently change our DNA (Julian Fidge, Rebekah Barnett, 2023-07-27)
Evidence (2023-07-27): The plaintiff, Dr Julian Fidge, alleges that Pfizer and Moderna's mRNA Covid-19 vaccine products contain genetically modified organisms (GMOs)[1], for which the companies did not obtain the appropriate licence[2] before distributing the products in Australia. [...] Genomics expert Kevin McKernan has found[5] that levels of DNA cell-substrate contamination in the mRNA Covid-19 vaccines are dangerously excessive, at anywhere between 18-70 times above legal limits. McKernan's findings have been replicated by other scientists[6]. [...] "Every single person who has been injected with these products has received a GMO that has not been through the expert regulatory process in this country. The human genome could be changed permanently, and no one was informed."
Claim: COVID-19 mRNA vaccines aren’t vaccines, according to court ruling (Alex Jones, Social media users, 2024-06-17)
Evidence (2024-06-17): Vaccines stimulate immunity to infectious diseases with the purpose of reducing the risk of disease transmission, severe illness, and death. By this measure, COVID-19 mRNA vaccines are indeed vaccines. Evidence from clinical trials and real-world data show that they reduce the risk of infection, serious illness, and death from COVID-19.
Claim: COVID-19 mRNA vaccines aren’t vaccines, according to court ruling (Alex Jones, Social media users, 2024-06-17)
Evidence (2021-09-27): The United States Supreme Court has not issued any ruling related to the COVID-19 vaccines or universal vaccinations, and there is currently no case on its docket involving challenges to vaccine mandates. [...] The Supreme Court has not issued any ruling related to the COVID-19 vaccines or universal vaccinations, and there is currently no case on its docket involving challenges to vaccine mandates. There is also no "universal vaccination" rule, although the federal government and many employers and institutions are tightening vaccination requirements. [...] PolitiFact, No, COVID-19 vaccines won’t alter your DNA and control you, Nov. 18, 2020
Claim: COVID-19 mRNA vaccines aren’t vaccines, according to court ruling (Alex Jones, Social media users, 2024-06-17)
Evidence (2022-02-22): In the wake of the US Supreme Court’s COVID-19 vaccine mandate rulings, medical groups and public health organizations expressed a mixture of relief and disappointment. On one hand, the nation’s highest court had upheld the Centers for Medicare & Medicaid Services (CMS) regulation regarding vaccination requirements for health care workers. On the other hand, the justices decided that the Occupational Safety and Health Administration (OSHA) did not have the authority to require vaccination or masking and regular testing for employees outside the health care system. [...] Yet Jha pointed out that "vaccine mandates are as old as our country," noting that General George Washington required his troops to be inoculated against smallpox. "It’s hardly un-American to have mandates," he added. "I couldn’t send my kid to a public school and say, ‘Sorry, no polio vaccine for my kid.’" Now that the Supreme Court has ruled against broad COVID-19 vaccine requirements, however, Jha said he is "deeply worried" that people are going to start unwinding mandates for vaccines against polio and other infectious diseases.
Claim: COVID-19 mRNA vaccines aren’t vaccines, according to court ruling (Alex Jones, Social media users, 2024-06-17)
Evidence (2022-01-14): The Supreme Court delivered 2 decisions on vaccine rules for U.S. workers [...] Ten million health care workers across the U.S. legally have to abide by the Biden administration's vaccine mandate. The Supreme Court upheld that rule yesterday. At the same time, the court blocked the vaccine-or-test rule that had been set for 84 million workers at companies. NPR's Andrea Hsu is here with details. Andrea, what did the court have to say? ANDREA HSU, BYLINE: Well, on the vaccine-or-test rule, the vote was 6 to 3 to block it. The six conservative justices found that OSHA, the federal workplace safety agency, did not have the authority to issue something so sweeping. They sided with the challengers, who had argued that COVID is not a danger specific to the workplace; it's all over society. And the court said OSHA can regulate occupational hazards but not public health more broadly without clear authorization from Congress. Now, the three liberal justices said the court's decision hinders the federal government's ability to deal with the very serious threat that the virus still poses to workers.
Claim: COVID-19 mRNA vaccines aren’t vaccines, according to court ruling (Alex Jones, Social media users, 2024-06-17)
Evidence (2023-10-21): Experts say there’s no evidence to support Kirsch’s claim that the mRNA COVID-19 vaccines are contaminated or contain ingredients that weren’t disclosed to regulators. [...] Experts said there’s no evidence that the mRNA COVID-19 vaccines contain previously undisclosed contaminants. Pfizer said noninfectious SV40 sequences were part of the starting material for the Pfizer vaccine, and the FDA and other regulators approved the vaccine manufacturing process. [...] Health Feedback, Claim that COVID-19 mRNA vaccines contain DNA contaminants based on study of vials of "unknown provenance"; no evidence COVID-19 mRNA vaccines can alter DNA in people, June 23, 2023