Secretin is a potent stimulus for bicarbonate secretion. Secretin also stimulates secretion of bile, release of Insulin, and release of Gastric Pepsin in the stomach. Secretin inhibits Glucagon release, intestinal motility, and prevents the uptake of water and sodium ions by the intestine. In normal patients, Secretin has little effect on Gastrin levels, but stimulates Gastrin greatly in Zollinger-Ellison patients. Secretin is also elevated in Zollinger-Ellison patients and in patients with duodenal ulcer.
Secretin levels are low in patients with pernicious anemia and achlorhydria.
Secretin secretion can be suppressed by Somatostatin, Cimetidine, and Methionine-Enkephalin. An interesting associated letter from Cyprus Autism and Secretin Autism Biomedical Information Network. Click on a list to view previous digests or to subscribe. Open to parents of children with autism and persons with autism, as well as the medical community. The list will not be censored in any way so as to promote the free flow of information between its members.