One can go along army roads from Dushanbe to Pakistan through China and along the Karakoram highway. Some of the most ancient routes of our planet that Marco Polo ascended are being rebuilt and used. The route from Bishkek to Kashgar through Naryn is very active with lots of trade. The trade traffic is dominated by Xinjiang. Han Chinese who are using this route are seen as hard bargainers.
Trade is a big factor in Kyrgyz balance sheet.
This border crossing is alive and well and plays an important role in the economies of both countries. We hear about the reopening the Great Silk road. Everyone is involved in this throughout Central Asia. But in actuality, Afghanistan is at the center of it all. It is likely that hopes and Silk road dreams are not going to be fulfilled to the extent that everyone hopes because the east west routes that go across Central Asia have to cross the Caspian and the Black Sea.