In addition to being uncomfortable, constipation can interfere with uptake of drugs such as levodopa. Eating a diet high in fiber and fluids reduces constipation. This condition is especially dangerous in PD, where falling is more common because of gait and balance impairment. Adequate intake of calcium and vitamin D help prevent loss of bone density. See your doctor for specific recommendations regarding your need for vitamin or calcium supplementation, if any.
Vitamin D reduces fracture risk .
This competition may prevent full absorption of levodopa, and reduce the efficacy of levodopa therapy, especially late in the disease. Dietary recommendations may include reducing excess protein in the diet, or consuming most of the day's protein at the evening meal. See your doctor for specific recommendations. Some evidence indicates that, at least in the test tube, antioxidants can reduce the cellular damage caused by free radicals . While there are no studies indicating that taking antioxidants such as vitamins A, C, and E will prevent or slow the disease, there is also no research suggesting that these vitamins are harmful at recommended dosages.