However, some very serious GI and renal complications may occur. Adults rarely can be affected. Eruptions usually last an average of 3 wk. The most common symptom is colicky abdominal pain. Large joints are most commonly involved, with pain and edema being the only symptoms.
Skin lesions consist of erythematous macules, urticarial papules and pruritic papules, and plaques.
Children under 2 y may also have upper extremity, head and trunk involvement. Typically, the rash first appears as red macules and papules, which later become purple, and then a rust color. There are usually varying stages of eruption present simultaneously. Heme positive stool is the primary GI exam finding. The abdominal exam is generally benign.