There are fewer responsibilities and restraints. New people and places. You will find these are additions to your life, not replacements, as you will also keep your family and old friends. Excitement to replace boredom. If it doesn't, rethink this lifestyle.
Travel equals education.
There is nothing quite like being there to learn about geography, history, archaeology etc. Crime rarely occurs in RV parks and campgrounds. There are basic questions which must be answered before attempting this life change. If you feel you cannot give it up the options are to rent or lease it, or to let it stand vacant. You will still have the bills and problems, but if you change your mind, you can still get it back.