Symptoms include shortness of breath, a non productive cough and fever. Lung toxicity is treated with steroids, but with limited success Eyes.- Long term use of busulphan may cause cataracts. This is seen in patients taking busulphan for more than 2-3 years. Neurological.- High dose therapy, such as that used in bone marrow transplant regimes, is associated with seizures. These patients are treated with anti-convulsant medications.
Seizures are rare in standard doses.
Gastrointestinal.-Diarrhoea and abdominal pain may occur with bone marrow transplant regimes. In these circumstances, dietary intake may need to be reduced. Avoid dairy products and maintain a good fluid intake. Nausea and vomiting is rare even at high doses. CanCare has been prepared for educational purposes only and is not designed to provide medical advice or professional services.