5.4 months for anterior uveal metastases. 9.3 months for orbital metastases Treatment Observation, resection, enucleation, chemotherapy, radiotherapy, and hormonal therapy. Enucleation for blind, painful eyes, solitary and low grade tumors, diagnostics. Most tumors are sensitive to radiation. Treatment is palliative.
Treatment is by external beam radiation or plaque radiotherapy.
30 Gy over 2-3 weeks is suggested course, but higher doses are common . Plaque radiotherapy results in lower overall dose of radiation. Reserved for solitary uveal metastases. At 1 to 3 months, regression occurs, typically without radiation side effects to retina, lens, or optic nerve. Time and sequelae of therapy relative to likely survival time is major consideration.