Acne Management Acne is a disorder of the sebaceous follicles. The sebaceous glands normally produce sebum, an oily substance that is secreted into the hair follicles.
Sebaceous glands are largest and most fully developed on the face, scalp, chest, and back.
The comedo is the primary lesion of acne. At times, acne may indicate a serious systemic disorder. Excess androgen production may be associated with acne in women. Benign hypersecretory states such as congenital adrenal hyperplasia should be considered, though polycystic ovaries are far more common. Severe, scarring, or unresponsive Isotretinoin administeredunder close guidance of a dermatologist Two topical retinoids, tretinoin and adapalene, are the most widely used comedolytic agents.