One of the five has a reverse circadian rhythm. This is possibly the result of the subject's sleep wake cycle. This subject stays up very late at night and sleeps during the day. The graphs at the end of this paper reiterate the fact that manual dexterity shows a circadian rhythm. The information from these data proves very useful in several areas other than science.
Transportation is a good example.
Pilots, truckers, ship captains, etc. who must travel around the clock, run into the risk of not being able to respond fast enough to a problem at hand. As seen in the above data, it is possible to reverse the circadian rhythm of manual dexterity. Large airlines could hire pilots who have these reverse reactions so on overnight flights they would be at their peak performance. Trucking and shipping companies could do the same. Doctors and nurses who begin working the night shift for the first time are at a large risk.