Diabetes most commonly occurs in middle age to older dogs and cats, but occasionally occurs in young animals. When diabetes occurs in young animals, it is often genetic and may occur in related animals. Diabetes mellitus occurs more commonly in female dogs and in male cats. Certain conditions predispose a dog or cat to developing diabetes. Animals that are overweight or those with inflammation of the pancreas are predisposed to developing diabetes.
Some drugs can interfere with insulin, leading to diabetes.
Glucocorticoids, which are cortisone-type drugs, and hormones used for heat control are drugs that are most likely to cause diabetes. These are commonly used drugs and only a small percentage of animals receiving these drugs develop diabetes after long term use. The body needs insulin to use sugar, fat and protein from the diet for energy. Without insulin, sugar accumulates in the blood and spills into the urine. Sugar in the urine causes the pet to pass large amounts of urine and to drink lots of water.