This is called practising the Dhamma until wisdom arises. When wisdom appears, Ignorance is eliminated. Dependent Origination can be broken up into different forms and subsequently analysed for meditators to understand and gain wisdom. They have to contemplate each step in turn in the Cycle. Extinction therefore takes place consecutively.
Wisdom arises followed by a clear comprehension in the Cycle of Existence.
There is no doubt left concerning birth, old age, disease and death. The vision of Truth will appear. The true nature of Suffering will be understood and this is followed by a weariness of birth, old age, disease and death. This realization will free one from the Cycle. The defilements, craving and attachment will be eliminated.