Use with caution in clients with impaired liver function, reduced hepatic blood flow, or impaired renal function. Initial increase in frequency, duration, or severity of angina. Pedal edema, flushing, increased angina, palpitations, tachycardia, other edema, abnormal ECG, hypotension, postural hypotension, syncope, MI, AV block ventricular extrasystoles, peripheral vascular disease. Dizziness, headache, somnolence, malaise, nervousness, insomnia, abnormal dreams, vertigo, depression, confusion, amnesia, anxiety, weakness, psychoses, hallucinations, paranoia. Asthenia, myalgia, paresthesia, hyperkinesia, arthralgia.
Treatment is supportive.
Monitor cardiac and respiratory function. If client is seen soon after ingestion, emetics or gastric lavage should be considered, followed by cathartics. IV calcium, dopamine, isoproterenol, metaraminol, or norepinephrine. Also, provide IV fluids. Place client in Trendelenburg position.