Hallucinations such as hearing voices, disordered paranoid thoughts. A few studies used American Veterans with schizophrenia as participants comparing brain abnormalities with state hospital patients or healthy men. Gray matter volume deficits and enlarges 3rd and lateral ventricles affecting cerebral cortex as a whole may be due to neurodevelopment displacement of neurons in white matter of schizophrenic patients. This may also be the reason for white matter surplus. Enlarged ventricals and reduced mass of cortical gray matter is an early neurodevelopment structure lesionprogressing with normal age-related changes.
Schizophrenia has a many contributing biological factors to the great amount of disability involved.
Many therapists have tried to identified this disease as an environmental outcome of stress. Yet, the abnormal brain strucutres found among many studies imply that schizophrenia is indeed a result of biological determinants. This gives researchers that ability to determine more appropriate treatments for such a devistating disease. Unfortunately, very little studies have been aplied to women with schizophrenia. It is important to find relationships with the disease and gender-related brain strucutes, to obtain the optimal pharmecutic therapy.