I usually go straight through a book, and in each chapter I ask the Holy Spirit to show me how the passage can apply to me. After meditating on my bible passage, I turn to prayer. I like the way Paul explains the work of the Holy Spirit in prayer. That means I am not alone in my praying. The Holy Spirit is interpreting the mind of God to me, and helping me put it into words.
Words are important.
I have a room where I can pray out loud. That helps me to be specific. It also gives me more confidence to be able to pray with others. I have various circles that are important to me, and I begin with my family and close friends. I don't just pray for their health and safety, but I express my concerns for them to enjoy all the good things that God has for them.