This course provides students with an introduction to the theory and methods of DNA and protein sequence analysis.
Students receive experience with retrieving information from sequence and genomic databases.
Methods of sequence alignments including dynamic programming and statistical methods are outlined. Emphasis is also placed on calculating the statistical significance of results. Protein structural alignments and displays, and structure prediction is covered. RNA structure prediction and RNA gene finding is also discussed. Gene prediction algorithms, methods of phylogenetic analysis, and database similarity searching are also explained.