Theory and practice of use of selected algorithms for solving problems of nucleic acid structure and sequence. Seminar presentations, faculty and guest lectures, and computer lab. This course is directed toward second year and later graduate students and postdoctoral fellows. Each term an important and thriving topic is selected for discussion based on the current literature. This course emphasizes both the molecular biology and biochemistry of various RNA molecules, including mRNAs, tRNAs, and rRNAs.
Special emphasis is on synthesis, molecules affecting stability, and degradation.