Tissues move tremendous distances within the early embryo to generate the vertebrate body plan.
Cells and tissues accomplish this feat through the use of patterned cell motility. To answer these questions involve the application of several different techniques from high resolution imaging of cell behaviors using low-light digital microscopy, conventional and multiphoton timelapse confocal microscopy coordinated with the measurement of tissue stiffness and force generation. Several approaches to understanding biomechanics in embryonic tissues. Histowiggling tissues to measure stiffness and force generation.