Cells are arranged in trabecular pattern. Nuclear pleomorphism is frequently seen making the diagnosis of malignancy very difficult. The diagnosis of certainty is by demonstration of metastasis. Catecholamines can be demonstrated histochemically. 8 Pheochromocytoma, Gross Image Fig.
Stress triggers the attacks.
MI, cerebral hemorrhage, and other complications may occur during paroxysms. High frequency of spontaneous regression. May involve both adrenals or be extra-adrenal. Tumors may differentiate to ganglioneuroma-Schwann cell type. Mets to retro-orbit, scalp, not infrequent.