The peak incidence occurring at the age of 40-50. The eruption occurs mainly in the groins, axillae, submammary areas and the flexor aspect of the limbs. The face is never affected, nor are the mucous membranes. Lesions usually start off as intact pustules which dry up within a few days, forming crusts or scales. Eruption tends to group together to form clusters with advancing edge.
Skin biopsy shows the presence of subcorneal pustules.
This condition occurs in hot and humid climate when babies are wearing too many clothes. It leads to blockage of the sweat ducts. Clinically, numerous monomorphic clear vesicles without surrounding erythema are seen on the skin, usually the trunk. Typically the skin remains dry. The disease is self-limiting.