Relationship with the administration of indapamide has not been proved in all cases. There have been no reports of overdosage. Based on the pharmacological activities of indapamide, overdosage may lead to excessive diuresis with electrolyte depletion. In cirrhotic patients, overdosage might precipitate hepatic coma. There is no specific antidote.
Treatment is symptomatic and supportive.
Induce emesis or perform gastric lavage. Correct dehydration, electrolyte imbalance, hepatic coma and hypotension by established procedures. Instead a non-diuretic antihypertensive agent should be added to the drug regimen. Alternatively if in the opinion of the physician, an important diuretic effect is desirable for the patient's control, a different diuretic which allows for dose titration could be tried instead of indapamide. Blister-packs of 30 and 100.