Animals carrying the virus are introduced into susceptible herds. Contaminated facilities are used to hold susceptible animals. Contaminted vehicles are used to move susceptible animals. Raw or improperly cooked garbage containing infected meat or animal byproducts is fed to susceptible animals. Susceptible animals are exposed to materials such as hay, feedstuffs, hides, or biologics contaminated with the virus.
Susceptible animals drink contaminated water.
A susceptible cow is inseminated by semen from an infected bull. Often blisters may not be observed until they have ruptured. Temperatures rise markedly, especialy in young animals, then usually fall in about 48 hours. Ruptured vesicles discharge either clear or cloudy fluid and leave raw, eroded areas surrounded by ragged fragments of loose tissue. Sticky, foamy, stringy saliva is produced.