It is believed that in depression, the neurotransmitters do not function as they should, interfering with communication between cells at important sites in the brain. 19 Antidepressant medications are thought to work by restoring neurotransmitter functions to normal. Lack of interest in sex can be a symptom of depression. 7 Healthcare professionals may ask questions about your level of interest in sex, and if your interest has recently decreased. If you or a loved one have started taking an antidepressant and you find that your interest in sex has diminished, that you are not physically able to become sexually excited, or that you no longer enjoy sex, talk to your healthcare professional.
Some antidepressants are more likely than others to interfere with sexual function.
13 Many people with depression are also prone to substance abuse. But after the initial intoxication, drugs such as alcohol worsen the depression. Healthcare professionals may ask about alcohol use to determine what part, if any, it plays in one's depressive illness. If you, a loved one, or a friend has symptoms of depression, it is very important that you or they speak with a healthcare professional. There are several places to turn for help and support.