Ecstasy has been involved in deaths due to severe dehydration and heat exhaustion, abnormal heart rhythms and liver failure. Ravers can reduce these risks by taking breaks and drinking plenty of non-alcoholic beverages. There is evidence that high doses of Ecstasy can damage brain cells. Effects of Long-term Use Using Ecstasy for a long time may also cause permanent chemical changes in your brain. These changes can mean that your mood and your sleep are disturbed for a long time after you stop using.
Some regular users become irritable, paranoid, or depressed.
They may experience flashbacks or psychosis. Repeated use can damage your liver. If you use drugs often, you can develop serious personal problems. Using drugs can become more important than your family and friends. You may continue using even when your job or schoolwork is suffering, or when you run into financial, spiritual or legal problems.