In the U.S., infection is characterized by a severe pulmonary syndrome with fever, generalized weakness and cough. The form of the disease that has been noted with lab animal exposure is characterized by fever, headache, generalized weakness and bleeding manifestations. Leptospirosis Leptospira interrogans Many animal species Through non-intact skin and mucous membranes. Often related to direct contact with urine or tissues of infected animals. Inhalation and ingestion may be possible routes.
Transmission can occur in utero and potentially by bite of an infected ectoparasite.
1 - 3 weeks. Influenza - like illness characterized by fever, generalized weakness and, headache. In severe cases, a discolored skin rash and enlarged lymph nodes can develop. Orf Poxvirus Wild ungulates Direct contact with virus - laden lesion exudates. Transmission by fomites or contaminated animals is possible.