Some proteins fold and unfold via single-exponential kinetics.
Such simple kinetics is usually interpreted in terms of Arrhenius or Eyring diagrams, and in terms of a transition state. But transition-state barriers explain why processes are slow, not why they are fast. The problem with proteins is to explain why they are fast. Using simple statistical mechanical models, we find that single-exponential kinetics is also explainable in terms of acceleration processes, rather than barriers. Handouts used at the event can be provided in alternative accessible formats upon request.