Experiments A Few Sample Projects 1. Students are asked to synthesize C 14 labeled methyl esters of several aromatic acids and to study their methanolysis. While ester synthesis is straightforward this synthesis requires some thought and trial experimentation since it must be done on a small scale in order to conserve expensive C 14 labeled methanol.
Student follow the methanolysis using a scintillation counter.
Each student group works on a different ester synthesis. We then summarize the class results and students correlate them using a linear free energy relationship. The P represents a phenyl group. . Alkylate the product with any alkylating agent that your group chooses. Consider the problem of C versus O alkylation.