Oftentimes, their doctors confidently tell them that if they are re-exposed to HIV their disease will progress more quickly. Other sexually transmitted diseases can threaten your health on their own or they can result in an upregulation of HIV replication and higher viral loads. No one knows. The lack of real data on the risk of reinfection may also be threatening efforts to keep negative people negative.
Some negative men think if they get infected, they can finally do away with condoms.
Dr. Bernard Branson, a researcher at the CDC and one of the founders of a community-based AIDS service organization in Maryland, has done comprehensive research on what's known, and not known, about the potential for reinfection. Unfortunately, the research findings are contradictory and inconclusive. One partner was infected by blood transfusion, and passed this infection to her partner sexually. They continued to have unprotected sexual contact. Analysis of the genetic sequences in this couple over time showed that the virus diverged separately in each individual.