Second-line treatment of Old World CL is topical aminosidine with methylbenzonium chloride bid for 10 days. See comments above on the promising use of oral miltefosine. Mucosal leishmaniasis is, itself, a complication. Secondary infections and associated problems are common. Culture and serologic tests are usually necessary.
Treatment is difficult and cure rates decrease with advanced disease.
Treatment is as for cutaneous leishmaniasis. Treatment of visceral leishmaniasis with amphotericin B colloidal dispersion. Practical guide for the treatment of leishmaniasis. Journal of the American Academy of Dermatology. W.B. Saunders Company.