This is the basis for immunity. Characteristics of the Immune System Specificity is the property of reacting with only one antigen. Each specific T cell or B cell only recognizes one type of antigen. Specific immunoglobulins recognize specific antigens. Characteristics of the Immune System Self-recognition is the ability to distinguish between self and nonself.
Tolerance is a state of unresponsiveness to a specific, known antigen.
Self-tolerance is gained during fetal development. Bone Marrow Bone marrow is the soft tissue in the hollow shafts of long bones. Like all other blood cells, lymphocytes are produced in the bone marrow. Thymus Located in the mediastinum. Both B and T cells are stored in the lymph nodes.