Try our On-Line Version of LogKow to examine the program's estimation ability and experimental database retrieval. The octanol-water partition coefficient is a physical property used extensively to describe a chemical's lipophilic or hydrophobic properties. P database retrieval system to predict water solubilities and dermal permeability coefficients, respectively. Enhanced features of the Windows version include batch-mode data entry and an expanded database of experimental values.
Users can see the structure that's being estimated.
Using a training set of 2,410 chemicals with 175 groups and 280 correction factors, a correlation coefficient of 0.98 was found between the experimental and estimated log K ow values. The method has been evaluated using a validation set of experimental values for 10,550 chemicals other than those included in the training set with a resulting correlation coefficient of 0.94 and a mean error of 0.35. Additional information concerning KowWin's accuracy is illustrated below. The figures below illustrate the LogKow program's ability to estimate accurate log P values.