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Unstable angina is a serious condition that can lead to a heart attack.
An estimated 1.5 million people worldwide were diagnosed with unstable angina in 1994, the last year for which figures are available. The condition is characterized by severe chest pain that signals the patient is at increased risk of heart attack and death. It is caused by a decrease in blood and oxygen to the heart muscle, and can occur when the patient is at rest or during minimal exertion. We found that 14 days after their last anginal episode, patients treated with Lovenox were less likely to suffer heart attack, death or recurring chest pain than patients administered unfractionated intravenous heparin. At 14 days, patients in the Lovenox group had a 16 percent relative reduction in death, heart attack or recurrent angina compared to the group given standard heparin.