My research program focuses on the neuroendocrine regulation of vertebrate reproduction and reproductive behaviors. Overall, we concentrate on the interaction of neuropeptides such as arginine vasotocin and gonadotropin-releasing hormone with gonadal and adrenal steroids. We use amphibians as model systems because of their simplified nervous systems and the sensitivity of their behaviors to neuropeptide modulation. We use a combination of techniques ranging from field experiments on behavior to molecular cloning of neuropeptide genes. We currently have four lines of investigation.
Vocal behavior is a critical component of the social behavior of frogs and toads.
We investigate how vocalizations are controlled by examining the sites and mechanisms of action of vasotocin and the gonadal steroids testosterone, dihydrotestosterone, and estradiol in the brain. Caecilian amphibians are unique in that most species are viviparous. Viviparity is rare in other amphibians. We are examining the neural and endocrine control of reproduction in caecilians to discover how they differ. This work includes study of brain, pituitary, gonadal, and fetal physiology.