Altered phenotypes discussed later. RNA and DNA viruses may transform cells. Malignant - no contact inhibition 3. Plasma membrane changes 7. Signal transduction in normal cells - signal perceived at surface of cell transduced to nucleus.
Tyrosine kinase phosphorylates tyrosine of target protein.
Effect - transcriptional activation 5. 7.9 kb genome, not cultured. Most have oncogenes 1. Particle morphologies - C, B, D types based upon nuclear location inside virion 2. Dominant vs recessive oncogenesis 1.