Neither breed is mentioned in several recent dermatological text books. In the UK, Flat coat retrievers are predisposed to soft tissue sarcomas producing nodules. This again is not mentioned. However, there is little doubt that the Boxer and related breeds have an international reputation for skin neoplasia. Age of onset.
Some diseases have a pronounced age predisposition.
Canine juvenile cellulitis syndrome is a disease of puppies usually less than 3 months of age. Histiocytoma is more common in dogs under 2 years. History of trauma including bite wounds. Trauma is an important part of the pathogenesis of nodules in the inflammatory infectious group. Dogs of working breeds are more predisposed to penetrating injury particularly with vegetable matter and may be more likely candidates for opportunistic infections.