The carrier state may be suspected by decreased RBC pyruvate kinase activity in the red blood cell. In newborns with dangerous levels of jaundice , an exchange transfusion may be recommended. If a splenectomy was done, the person should receive pneumococcal vaccine at recommended intervals. The outcome varies. Some people have few or no symptoms, others have severe symptoms.
Treatment is usually successful in reducing the severity of symptoms.
Call you health care provider ANY time that jaundice develops. Call for an appointment with your health care provider if you have a family history of this disorder and you plan to have children.