The resume has been prepared, you've researched all the prospective companies where you would like to work, you're networking everywhere, and responding to ads by the hundreds. Perhaps it's time to take a look inside. Just the act alone of a negative thought is enough to blow you out of the water. The universe will respond to your negative thoughts just as certain as it will respond to a positive one. Every thought creates a force of energy, be it good or bad, contributing to an end result.
Success results from attitude as much as aptitude.
That is why having the right attitude is crucial to whatever it is you seek in life. You don't need more strength, or more ability or greater opportunity. What you need is to use what you have. The golden opportunity you are seeking is in yourself. There will always be a new frontier where there is an open mind and a willing hand.