Test A test used for evaluation of the extrinsic and common coagulation pathway and for monitoring oral anticoagulant therapy. Reagent Substance employed to produce a chemical reaction in order to measure quantities, pertaining to other substances. Stability Ability of a system, when kept under specified conditions, to maintain a stated property value within specified limits for a specified period of time. Systematic Error of Measurement Mean result of a large number of repeated measurements of the same measurable quality minus a true value of the measurable quantity. A potent coagulation enzyme, formed from prothrombin, which circulates in the blood.
Thrombin reacts with fibrinogen during the clotting process.
A test used to evaluate the final steps of the coagulation pathway. The TT is the time in seconds required for a fibrin clot to form in a sample after a known amount of thrombin has been added. Thrombus A clot in a vein or an artery that obstructs the free flow of blood. Thrombosis in a coronary artery, which supplies the heart, results in a myocardial infarction. If this process occurs in the brain, the patient experiences a stroke.