Weight loss appears to be an effective method for primary prevention of hypertension.
However, the long-term effects of weight loss on blood pressure have not been extensively studied. Multicenter, randomized clinical trial testing the efficacy of lifestyle interventions for reducing blood pressure over 3 to 4 years. Participants in TOHP II were randomly assigned to one of four groups. The weight loss intervention included a 3-year program of group meetings and individual counseling focused on dietary change, physical activity, and social support. Mean weight change from baseline in the intervention group was 4.4 kg at 6 months, 2.0 kg at 18 months, and 0.2 kg at 36 months.