The human genomic research programme at the Sanger Centre encompasses mapping, sequencing, and structural and functional interpretation.
Some groups work on specific chromosomes.
Others are devoted to whole genome mapping, developing resources, or automation, data-handling and analysis. Additional groups are involved in discovering ways of analysing sequences, comparisons with other genomes, studying the structure and expression of genes, identifying polymorphisms, and examining chromatin structure in relation to function. These studies will contribute to the annotation of the human genome sequence and ultimately will provide a detailed and informative picture of the human chromosomes, genes and their biological function. The plan to determine the complete human sequence map by an international collaborative effort was outlined during 1995. The agreed aim is to produce the sequence chromosome by chromosome.