We know that we can get the health benefits of protection from osteoporosis and heart disease, and relieve symptoms of menopause with this product. For convenience, Premarin is also now available in combination products that contain progesterone in one tablet. PremPro contains Premarin, plus a small dose of progesterone in each tablet. PremPhase contains the same two ingredients, but it has varying amounts of progesterone throughout the month. PremPhase more closely matches the cycles our body would have produced, but PremPro is not as likely to cause breakthrough bleeding.
Some women object to taking Premarin tablets because of the way it is manufactured.
Premarin contains a combination of estrogens that are extracted from pregnant horse urine. If you find this objectionable, there are a variety of other products available that do not require animals for production. Examples include Estrace, Estratab, or Ogen. Newer combination products include Ortho-Prefest and Femhrt. Estrogen is also available as a patch.