Even the most brilliant act of human genius, in the final analysis, is an act of trial and error. Error, whether random or deliberate, must become an integral part of any process of creation. Evolution can be thought of as systematic error management. A complicated structure has many masters and none of them can be served exclusively. So vast are the mingled drives in any complex entity that it is impossible to unravel the actual causes of its survival.
Survival is a many-pointed goal.
Most living organisms are so many-pointed they are blunt variations that happen to work, rather than precise renditions of proteins, genes, and organs. Equilibrium is death. Yet unless a system stabilizes to an equilibrium point, it is no better than an explosion, and just as soon dead. A Nothing, then, is both equilibrium and disequilibrium. Honing in on that liquid threshold is the still mysterious holy grail of creation and the quest of all amateur gods.