Each Combivir tablet contains lamivudine 150mg and zidovudine 300mg. The dose of lamivudine may be lowered if you have serious kidney problems. If you do miss a single dose of lamivudine, take the missed dose immediately . Then, take the next dose at the scheduled time. Side effects include headache, nausea, fatigue, and decreased appetite.
Some people have difficulty sleeping.
These side effects are likely to get better or even disappear over time. Lamivudine may help suppress the hepatitis B virus. If you are infected with hepatitis B, it is very important that you avoid abruptly stopping lamivudine because this may allow hepatitis B to multiply and damage your liver.