The mind is alienated and becomes an enemy of God by wicked works. Wicked works poison the mind toward God. Wicked works turn the mind away from and make the mind hostile to God. Sin is not a passive plaything that you can take up in your hands. Sin is a power that seeks to control the mind, how you think, your attitude, and fundamentally how you think and your attitude toward God.
Sin is the great mind-distorter.
Wicked works do not leave you. They do not stay behind you in the bar, in the movie house, in the bedroom. But they infiltrate your thinking toward God. They want to turn you in hostility against God. A man who takes a mistress does not return to his wife the same, but is alienated in his mind toward her.