Antiphospholipid antibody syndrome is associated with abnormal decidual vascularization and thrombosis of decidual vessels with abruption. Ascending infection leads to membrane rupture and premature delivery. Anatomic cervical incompetence can also lead to miscarriage. Estimates of the percentages of conceptions that fail to reach term has increased with the advent of early detection methods. Increasing spontaneous abortion rate with age.
Some women are habitual aborters.
Alternatively the fetus may be delivered within the amnionic sac followed by the placenta. Findings vary with etiology of the loss. Common to all is an implantation site with acute hemorrhage and inflammation. Decidualized endometrium is generally sloughed as well. The villi may show infarct or intervillositis in cases associated with euploidy.