Some might suggest methylprednisolone in a regimen similar to traumatic spinal cord injury, or another regimen of steroid for the acute syndrome. For penetrating trauma, steroids have not shown significant benefit. Surgery is controversial. The timing of decompression is controversial, with immediate, early, and late surgical decompression showing varying results. Early consultation regarding the use of steroids and any specific regimen is encouraged.
Steroids have anti-inflammatory properties and cause profound and varied metabolic effects.
In addition, these agents modify the body's immune response to diverse stimuli. They may decrease edema around nerve root segments. One possible regimen might be the dose employed in traumatic spinal cord injuries, but no studies exist to support this over any other regimen. Ideally, the admitting physician or service should examine the patient at the time of admission. Patients with CES should be considered for transfer if appropriate subspecialty care is not available.