Second, all stain removal solutions should be applied before throwing clothes in the washing machine. If you have those kinds of stains, blot up all you can with a clean cloth and sponge with cool water. Rub the stain with heavy-duty liquid detergent and wash in the hotest water safe for the fabric. If you spill soda, immediately soak or blot the stain with cool water. Dark sodas such as coke or pepsi contain sugar and caramel.
Water is usually all that is needed to remove caramel.