Prepared and published by Update Software Ltd . All rights reserved. Cochrane reviews are regularly checked and updated if necessary. Tamoxifen is an important drug for treating breast cancer. Ovarian cancer cells are known to possess receptors for hormones and may thus also respond to tamoxifen.
Tamoxifen is used to treat breast cancer in women whose tumours have oestrogen receptors.
Since ovarian cancers also commonly have oestrogen receptors, it has been suggested that tamoxifen may be of some benefit. The objective of this review was to assess the effects of tamoxifen in women with relapsed ovarian cancer. We searched the Cochrane Gynaecological Cancer Group trials register and references from relevant articles. We also contacted researchers and drug companies. Only trials involving 10 or more patients were included.