Treatment is most effective when initiated within six hours of exposure.
HBO 2 treatment must be predicated more on the clinical picture than the carboxyhemoglobin levels. HBO 2 hastens the disassociation of carbon monoxide from hemoglobin, myoglobin, cytochromes and other hemoproteins. At sea level, oxygen has not been shown to antagonize lipid peroxide while HBO 2 does. HBO 2 also provides tissue oxygenation via saturated plasma. A Committee Report .