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To subscribe, E-mail the words . . If the Senate approves this bill, it will effectively end government regulation of health, safety and environment. This is not an exaggeration. Therefore, nearly all regulations worth passing will be covered by this law. Where conflicts among such data appear to exist, or where animal data is used as a basis to assess human health, the significant risk assessment document shall, to the extent feasible and appropriate, include discussion of possible reconciliation of conflicting information, and as relevant, differences in study designs, comparative physiology, routes of exposure, bioavailability, pharmacokinetics, and any other relevant factor, including the sufficiency of basic data for review.