Probucol and multivitamins in the prevention of restenosis after coronary angioplasty. Subjects continued treatment for six months following angioplasty. Baseline and follow-up angiograms were used to determine the rate and severity of restenosis. Each was assessed by a blind investigator. Multivitamins had no significant effect on the rate of angiographic restenosis or on major clinical end points.
Simvastatin reduces graft vessel disease and mortality after heart transplantation.
Seventy-two heart transplant patients were randomly assigned to receive diet plus simvastatin therapy or just dietary therapy and were followed for a period of 4 years. Passive cigarette smoking and reduced HDL cholesterol levels in children with high-risk lipid profiles. One hundred three subjects were studied and information on demographics and exposure to passive smoking were obtained via mail survey and telephone survey. The first lipid clinic visit was subsequent to the mailed survey. Twenty-seven percent of subjects came from households with cigarette smokers.