It is spread via genital, oral, and anal sex. A painless sore usually appears at the point of sexual contact. Sometimes the sore is unnoticed.
Swollen glands can develop about a week after the sore appears.
If not treated, the sore will disappear, but the infection still lives in the body. Approximately six weeks after the sore first appears, the infected person will enter the second stage of the disease. A rash will appear on any part of the body. Other symptoms include fatigue, fever, sore throat, headache, loss of appetite, and swollen glands. These will last 2-6 weeks, and disappear if not noticed.