The test is based upon extraction followed by reverse phase HPLC with UV detection. It quantitates approximately 6 antioxidants such as BHT, Irganox products, and Tinuvin. The preferred leachate liquid is water, saline, or acetonitrile. The preferred leachate liquid is water or dilute sodium hydroxide. The preferred leachate liquid is water or saline.
Silicones are common in containers and medical devices.
While such silicones are generally very insoluble in water, lipophilic components may leach low molecular weight fractions of the silicone. Also, some water soluble silicones such as Simethicone, are used as surfactants and anti-gas additives. The preferred leachate liquid is water or saline. The preferred leachate liquid is water. This test includes over 60 elements.