Although entropion can be corrected surgically, affected dogs are more likely to produce affected offspring, and this condition occurs in some bloodlines of Anatolians. This is a disease with multiple, wide-ranging effects on a dog's health. Individual dogs that are afflicted can be treated with thyroid medication, but the treatment is a lifelong proposition. Some breeders have started testing their breeding stock for normal thyroid function. Finally, there is some evidence that Anatolians are slow to build up immunity to parvovirus.
Some breeders use special vaccination schedules for their breeding stock and young puppies.
Reputable breeders guarantee their puppies against any inherited health defects.