However, with time, the clear spaces become involved with opacity. This later onset opacity in the previously clear spaces is usually much more superficial than the longstanding, dense white granules. The vision declines dramatically when the clear spaces opacify. Masson s trichrome will stain deposits bright red. Masson s trichrome will stain deposits bright red.
Some physicians treat recurrent erosions with frequent antibiotic ointments while awake.
Excimer laser PTK is quite effective at removing opacities from the superficial cornea. When deep opacities are causing significant visual symptoms, corneal transplantation may be required. Excimer laser PTK will remove superficial opacities, smoothen the corneal surface, and allow the epithelium to re-adhere more tightly. If the visual acuity drops and the majority of the opacities are deep, lamellar or full thickness corneal transplantation can be performed. Although the success rate for corneal transplantation is very high, granular deposits will recur with time.