Welcome to GoLive CyberStudio Publications of Special Significance 109. Unfolded conformations are more stable than the native state of a -lytic protease. Salt bridge relay triggers defective LDL receptor binding by a mutant apolipoprotein. Topologically constrained phase refinement for macromolecular crystallography. A computational method for the design of enzymes with altered substrate specificity.
Structural plasticity broadens the specificity of an engineered protease.
Optical sectioning microscopy.