Trizivir is taken twice daily, one tablet in the morning and one tablet in the evening, either on an empty stomach or with food. Because Trizivir combines a single dose of three drugs into one pill, it might be easier for people living with HIV to take. Trizivir should not be any more or less effective than AZT, 3TC, and abacavir taken together. Trizivir has been studied in clinical trials involving people who had never taken AZT, 3TC, or abacavir in the past. The side effects of Trizivir will likely be the same as those seen in other patients taking AZT, 3TC, and abacavir in combination.
Some patients are allergic to abacavir.
If you develop a rash, fever, or respiratory problems while taking Trizivir, inform the research nurse or medical investigator of the study you are participating in immediately. Also be sure to tell your own doctor if any of these, or other, side effects occur. You may not be able to take Trizivir, or you may require a lower dose or special monitoring during treatment if you have any of the conditions listed above. You may not be able to take Trizivir if you have a history of pancreatitis. Do not take Trizivir if you have ever had an allergic reaction to it in the past.