Visual problems progressing to blindness may be the first symptom. Genetic counseling is recommended for prospective parents with a family history of Krabbe disease. Carrier states may be recognized by decreased galactocerebroside beta-galactosidase levels in their white blood cells or skin fibroblasts. Prenatal diagnosis is possible by measuring galactocerebroside beta-galactosidase levels in cultured amniotic fluid cells or from cultured chorionic villi cells. There may be signs of deafness .
Treatment lies in prevention.
The outcome is likely to be poor. Call your health care provider if your child develops symptoms of this disorder. Seizures and change in muscle tone are emergency symptoms, as is a loss of consciousness or abnormal posturing .