Surgically removing the tumor is the only way to eliminate the pain permanently. Rather than undergo surgery, some people prefer to take aspirin indefinitely. Giant cell tumors usually occur in people in their 20s and 30s. These tumors most commonly originate in the ends of bones and may extend into adjacent tissue. They usually cause pain.
Treatment depends on the tumor's size.
A tumor can be surgically removed, and the hole can be filled with a bone graft or a synthetic bone cement to preserve the bone's structure. Occasionally, very extensive tumors may require removal of the affected segment of bone. About 10 percent of the tumors recur after surgery. Rarely, these tumors become cancerous. Primary Cancerous Bone Tumors Multiple myeloma, the most common type of primary cancerous bone tumor, originates in the bone marrow cells that produce blood cells.