A closure or obstruction in a peripheral artery, such as in a limb, which prevents oxygenated blood from reaching the tissues. Symptoms of pain in the limb with exercise, which is relieved by rest.
Symptoms lessen after a period of rest.
Symptoms of pain in the leg when at rest, with or without gangrenous ulcers. Limitation of walking. Need for surgery or re-operations. Gangrene, leading to leg amputations. Anti-platelet therapy, usually aspirin or clopidogrel or ticlodipine.