The different sentry modes that you can set a character to range from neutral to trigger-happy and depending on the setting, the character will act accordingly. Taking a specific shot takes more action points and the percentage of a hit is reduced. Distance, lighting, perception, and gun familiarity play a big part in deciding if you will get a hit or not. The story unfolds itself at every mission. Following a linear path, more weapons of greater power become available as well as new and more dangerous enemies.
Tactics do play a big part in the game as the levesl do become increasingly more difficult.
In single-player mode you can only play as humans, but in multiplayer they range from mutants to ghouls. You can go about and frag friends in a slower skirmish network game. Overall the game was very enjoyable. The music, controls, movies and briefings only enhanced overall game play. The core of the series was a solid base to build from and this game really reflected that.