Inflammatory reactions within the dermis consist of lymphocytes and a small number of plasma cells. These are all nonspecific dermotopathologic features that may be found in many pathological vulvar conditions as. The recent change in the nomenclature points out to describe squamous cell hyperplasia when other causes of hyperplastic epithelial changes are excluded on the basis of specific anatomical-clinical features. The relief of itching seems therefore the first aim of any therapy. If symptoms of anxiety and irritability re present, oral tranquillizers may be used, especially at bedtime.
Topical corticosteroids are the mainstay of therapy for squamous cell hyperplasia.
The fluorinated compounds in cream or ointment vehicles, applied twice daily will generally cure the lesion. If the vulva is extremely thickened and a large area is involved with squamous cell hyperplasia, a Class 1 topical steroid may be required. Generally though, squamous cell hyperplasia can be treated with a short term Class IV steroid. If an antihistamine is added, the antipruritic effect will be improved. Rarely it is necessary to inject triamcinolone acetonide .