Comment on both enzymes and what they act on. Describe the role of telomerase in telomere formation. Trisomy 13 is known as Patau syndrome. The following pair of chromosomes is present in an inversion heterozygote.
X marks the placement of the centromere.
Illustrate each by sequence and describe the chromosome. Contrast the functional differences between an oncogene and a tumor-suppressor gene. Some XY individuals phenotypically present as females and some XX individuals as males. Describe tautomerism and the way in which this chemical event may lead to mutation. Explain briefly the yeast two-hybrid method and how it relates to transcriptional regulation.