Matthew Henry interprets this verse to mean that Satan attacks us even at our highest spiritual experience. He can distract you from hearing the Word in church. Just because you are in Bible school does not mean that he will attack you less. Even while in your prayer closet you should be on guard. Try as we might, this victory over sin will never be achieved by human means.
Wrestling requires a close-up encounter with our competitor.
We will be responsible for taking the necessary means to prepare for this battle. This is a fight to the death. The people of Ephesus had already become aware of the aggressive nature spiritual forces posed against them. Evil spirits were cast out when they came into contact with Paul s clothing. The Holy Spirit impressed upon Paul his need to visit Jerusalem.