1995, Lawrence HJ, Sauvageau G, Ahmadi N, Lau T, LeBeau MM, Link M, Humphries K, Largman C. Stage and lineage-specific expression of the HOXA10 homeobox gene in normal and leukemic hematopoietic cells. Over-expression of HOXB4 in hematopoietic cells causes the selective expansion of more primitive populations. 1995, Sauvageau G., Thorsteinsdottir, U., Eaves C.J., Lawrence H.J., Largman C., Lansdorp P.M., Humphries R.K. Over-expression of HOXB4 in hematopoietic cells causes the selective expansion of more primitive populations in vitro and in vivo. 1996, Helgason C.D., Sauvageau G., Lawrence H.J., Largman C., Humphries R.K. Overexpression of HOXB4 enhances the hematopoietic potential of embryonic stem cells differentiated in vitro. R.K. Overexpression of HOXA10 in murine hematopoietic cells perturbs both myeloid and lymphoid differentiation and leads to acute myeloid leukemia.
T lymphocytes an progressive myeloproliferation.
1997, Magli, M.C., Largman, C., Lawrence, H.J. Effects of HOX homeobox genes in blood cell differentiation. Stelnecki, E.J., Komuves, L.G., Kwong, A.O., Holmes, D., Klein, P., Rozenfeld, S., Lawrence, H.J., Adzick, N.S., Harrison, M., Largman, C. HOX homeobox genes exhibit spatial and temporal changes in expression during human skin development. All Rights Reserved.