Osseous defects and congenital dislocations . These lesions all relate to neurofibromas near or within the affected bone. Oral Pathology . Endocrine disorders . Gastrointestinal involvement .
Secondary hypertension is a frequent finding in adults with neurofibromatosis.
The cause may either be renovascular, or pheochromocytoma, or both. In affected patients under eighteen years of age, renovascular hypertension is a seven times more likely cause of hypertension than pheochromocytoma. Medical and endovascular treatments have, to date, had poor long-term outcomes. Surgical reconstruction remains the therapy of choice. Vascular anomalies .