Evidence that intensive management of blood glucose reduces and may prevent development of microvascular complications of diabetes. Demonstration that antihypertensive drugs called ACE-inhibitors prevent or delay kidney failure in people with diabetes. Researchers continue to search for the cause or causes of diabetes and ways to prevent and cure the disorder. Scientists are looking for genes that may be involved in type 2 diabetes and type 1 diabetes. Some genetic markers for type 1 diabetes have been identified, and it is now possible to screen relatives of people with type 1 diabetes to see if they are at risk for diabetes.
Similar research is carried out at other medical centers throughout the world.
Transplantation of the pancreas or insulin-producing beta cells offers the best hope of cure for people with type 1 diabetes. Some pancreas transplants have been successful. However, people who have transplants must take powerful drugs to prevent rejection of the transplanted organ. These drugs are costly and may eventually cause serious health problems. Scientists are working to develop less harmful drugs and better methods of transplanting pancreatic tissue to prevent rejection by the body.