The illustration shows a normal cell is dying. In dying cells, the phospholipids inside flip to the outside. When something is abnormal with the antibody or the b 2-glycoprotein 1, a blood clot develops. What happens most frequently in APS is blood clotting. Pregnancies are lost because blood clots form in the placenta and starve the baby of nutrition.
Treatment is the use of anticoagulation.
In pregnancy, heparin is used. However, pregnancies are not normal. Normal pregnancy is 40 weeks. Heparin protects placenta partially, but not fully so that the baby gets enough nutrition to survive longer in the mother. Once born, the babies do fine.