The presence or absence of stromal heterologous elements, the types of such elements, the grade of the stromal components, and the mitotic activity of the stromal components bear no relationship to the presence or absence of metastases at surgical exploration. The type of heterologous sarcoma had no effect on the progression-free interval.
Surgery alone can be curative if the malignancy is contained within the uterus.
The value of pelvic radiation is not established. Current studies consist primarily of Phase II chemotherapy trials for advanced disease. Omura GA, Blessing JA, Major F, et al. I uterine sarcomas.