Age of onset from 1 to 8 years, peaking at 3 to 5 years. More prevalent in boys than girls. The maximal voltage area is usually anterior. There is disagreement as to whether polytherapy or monotherapy is better. The precise drugs used will depend on the types of fits for a particular child.
Typical drugs used include valproic acid, clonazepam, vigabatrin , felbamate and topimirate.
ACTH can be used successfully for short periods, but the child will usually regress afterwards. The ketogenic diet appears to work well with some children, although there are no useful clinical studies. The Lennox-Gastaut Syndrome Support Group was formed in 1997, in the UK, by parents of children suffering from Lennox Gastaut syndrome. The group aims to provide support and information about this debilitating condition and its consequences for the child. Membership is open to all parents of children with Lennox-Gastaut syndrome.