A reasonable level is 50 mg per day. Early reports suggested St. John's wort improved depression by a mechanism similar to the action of Nardil. This theory now appears to be incorrect. Nonetheless, some doctors of natural medicine still believe it makes sense to avoid combining St. John's wort with Nardil or other monoamine oxidase inhibitors until more is known. So far, there have not been consistent reports of problems when the two are taken together.
Scotch broom is high in the chemical tyramine.
Therefore, scotch broom and Nardil and related drugs should not be combined. Pyridoxine deficiency and peripheral neuropathy associated with long-term phenelzine therapy. H lzl J, Demisch L, Gollnik B. Investigations about antidepressive and mood changing effects of Hypericum perforatum. St. John's wort, Hypericum perforatum. In American Herbal Pharmacopoeia and Therapeutic Compendium, ed.