Dalmation toadflax is adapted to a wide range of soil and environmental conditions, but thrives on coarse textured well-drained soils in open areas along roadsides and in rangelands and some cropping systems. Disturbance appears to be closely related to the invasion potential of dalmation toadflax. Initially, seedlings are poor competitors and establishment is difficult where competitive vegetation is present. However, established plants compete very strongly for limiting resources. Dense stands reduce grazing capacity and may displace native plants.
Seeds are very small and are adapted for wind dispersal.
Dalmation toadflax has an extensive underground network of lateral roots with numerous dormant root buds. Complete removal of the root system is generally infeasible. Mowing generally provides very limited control of dalmation toadflax. Mowing may prevent seed production, but does not appear to significantly deplete root carbohydrate reserves. Mowing also reduces the competitive effects of surrounding vegetation.