Although it is relatively safe, it is expensive and not without risks. Its effects in children who are not GH deficient are less well established. Studies have shown that it is effective in stimulating growth in girls with Turner syndrome and children with chronic renal insufficiency, but there is less information about long-term effects of treatment in these children. GH therapy requires a long-term commitment by the child and family in order'to achieve the best possible response. The medication is given by injection, with the prescribed dose divided into between three and seven shots per week.
Treatment usually continues until the child has completed puberty or has stopped responding.
Responsibility within the family for giving the medication may change from time to time, but it must be clearly defined. The child's response to GH therapy should be monitored closely by a pediatric endocrinologist. This usually means visits to the doctor every three to four months with periodic laboratory and X-ray evaluations and dose changes. GH therapy is expensive. Reimbursement may be available from health insurance, Medicaid or state children's health programs.