As a general rule of thumb, these values should be within normal adult ranges at weaned sales age. Factors which reduce erythropoesis will cause non-regenerative anemia. These include infectious disease, cachexia, neoplasia, and certain toxins. The most common etiologies of non-regenerative anemias in pet birds are of infectious origin. Mycoplasma infections in pet birds are not well-documented as a cause of anemia.
Viral infections can also cause non-regenerative anemia.
Cessation of NRA is characterized by increasing RBC count, increased PCV, increase in immature erythrocytes, increase in anisocytosis, and increased polychromasia. When the clinician manages treatable infectious etiologies, cessation of NRA gives an improving prognosis. Wasting diseases and neoplasia often result in anemia, due to catabolic influences. Renal failure anemia is not frequently noted. This may be partly due to difficulties in early clinical and biochemical recognition of renal dysfunction.