This can only be used in females. A water pill called spironolactone can also be effective. Abnormal and excessive sloughing of the cells that form the inner lining of the gland. Isotretinoin also decreases the sloughing of cells and can be quite effective. Oral antibiotics also have an indirect effect on improving this problem.
Topical medication is quite effective in decreasing the sloughing of cells.
Proliferation of bacteria called Propionibacterium Acnes. This results in an inflammatory reaction and makes the acne appear very red and sometimes swollen. Oral medications for this include tetracycline, erythromycin, minocycline, doxycycline, Bactrim, clindamycin and isotretinoin. Topical medications to reduce the bacteria include erythromycin, clindamycin, benzyol peroxide and azelaic acid. A combination of benzyol peroxide and erythromycin is extremely effective and goes by the brand name of Benzamycin.