Vulvar cancer is highly curable when diagnosed in an early stage.
Survival is most dependent on the pathologic status of the inguinal nodes.
A multifactorial analysis of risk factors in squamous vulvar cancer demonstrated that nodal status and primary lesion diameter, when considered together, were the only variables associated with prognosis. These discriminants were most useful within FIGO stage III disease. Vulvar cancer is primarily a disease of elderly women but has been observed in premenopausal women as well. It is most commonly squamous cell carcinoma in type, although other histologic types do occur. In many cases, the development of vulvar cancer is preceded by condyloma or squamous dysplasias.