A case of phrynoderma with perforating folliculitis, reported by Neill et al., responded to 50,000 units of vitamin A daily for 1 month, followed by 2000 units per day. Hurwitz found that a combination of antistaphylococcal therapy, phototherapy and a topical corticosteroid lotion was helpful in controlling the condition in patients with chronic renal failure. Despite the one negative result with aromatic retinoids, such agents may play a role in the treatment of some cases of perforating folliculitis. However, there is not sufficient experience with these agents to allow recommendation of a particular dosage schedule. Inpatient care is not required for this cutaneous condition.
Skin lesions can improve or clear, either spontaneously or with therapy.
Hopefully, further therapeutic experience will permit development of specific treatment guidelines. Typical appearance of lesions of perforating folliculitis, consisting of keratotic follicular papules. I. Clinical findings in five cases and review of literature. The evolution of perforating folliculitis in patients with chronic renal failure. Perforating folliculitis and psoriasis.