Studies range from the molecular to the clinical.
We are interested in host cell-mediated immune responses to HIV and their role in both protection and immunopathology. We study mechanisms of resistance to current antivirals and combination therapy strategies to overcome resistance. Studies on lymphocyte expansion and immune reconstitution of subjects infected with HIV-1 are also underway. Merrill, D.P., Moonis, M., Chou, T.C., Hirsch, M.S. 1996. Oh, M.D., Merrill, D.P., Sutton, L., Hirsch, M.S. 1997.