Recurrent VVC does not appear to be the result of resistant vaginal yeast. Male partner should be examined for the presence of penile colonization of candida although it has not been confirmed that treatment of men prevents recurrence in women. In recurrent VVC, long-term maintenance with a suppressive prophylactic regimen may be required. Immunocompromised patients are prone to candida infection. Oral candidiasis and VVC is common in patients with HIV infection.
Systemic antifungal is required if topical therapy fails.
Systemic antifungal agents is required for the treatment.