Symptoms include intermittent hypoglycemia and metabolic acidosis, sometimes resulting in coma. Fatty changes in the liver may also occur. Treatment involves prevention of prolonged fasting to prevent symptoms. G6PD deficiency is the most common genetic enzyme deficiency, occurring most often in tropical and subtropical Asia, tropical Africa, areas of the Mediterranean, the Middle East, and New Guinea. Severity of the condition is extremely variable.
Treatment involves restricting exposure to pathogens that cause a reaction.
Incidence in newborns varies according to viral status of the mother. Initially, HIV is asymptomatic. Young children, however, have a much shorter incubation period and generally develop symptoms within two years. Symptoms include wasting, fatigue, fever, oral thrush, rashes, and superinfection with opportunistic organisms. Treatment involves chronic use of antiviral drugs to slow progression of the virus and allow the immune system to recover.