Sugar lowers the enzymes' ability to function. Sugar can cause loss of tissue elasticity and function. Sugar can cause liver cells to divide, increasing the size of the liver. Sugar can increase the amount of fat in the liver. Sugar can increase kidney size and produce pathological changes in the kidney.
Sugar can overstress the pancreas, causing damage.
Sugar can increase the body's fluid retention. Sugar can cause constipation. Sugar can compromise the lining of the capillaries. Sugar can cause hypertension. Sugar can cause headaches, including migraines.