In the most extensive clinical trial to date a high dose of 75 milligrams of Melatonin per day was given to 1400 women in the Netherlands for up to four years with no ill effects. Melatonin should only be taken at nighttime, usually about thirty minutes prior to going to bed. Take it at the same time every evening. I am currently working on the snail mail newsletter which is due out in June. All Rights Reserved.
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