Research published in 1999 demonstrates that in the lab, a natural parasite of frogs can cause some types of deformities and may be a cause in the field of deformities in some places, particularly along the US west coast. There are many other examples of synergistic interactions in the scientific literature. And health risks of endocrine disrupting chemicals are of concern with or without synergistic interactions among chemicals. Both phytoestrogens and xenobiotic estrogens can can cause harm. Sperm count has clearly fallen in some geographic areas, and not in others.
Studies demonstrate that people have been affected by endocrine disruption.
Industry's failure here tells more about the incompetency of their attempts than the value of vom Saal's research. Moreover, vom Saal's research has now been confirmed by two separate laboratories. These studies, moreover, say nothing about whether weakly estrogenic contaminants cause breast cancer.