The papule ultimately ulcerates. The ulcer has raised edges with surrounding dusky red skin. The ulcers can be moist or open with seropurulent exudate or dry with a crusted scab. Sores usually are found on exposed areas of skin, especially the extremities and face. Regional adenopathy, satellite lesions, and subcutaneous nodules can be present.
Untreated sores can leave depigmented, retracted scars.
Mucocutaneous leishmaniasis Cutaneous lesions can be single or multiple. Mucosal lesions often develop after the primary lesion has healed. They can progress to involve the entire nasal mucosa and the hard and soft palates. Without treatment, the entire nasal mucosa and palates will become deformed with ulceration and erosion of the nasal septum, lips, and palate. Pancytopenia is common.