Sevelamer hydrochloride is hydrophilic, but insoluble in water.
Each film-coated tablet of Renagel contains either 800 mg or 400 mg of sevelamer hydrochloride on an anhydrous basis. The inactive ingredients are hydroxypropyl methylcellulose, diacetylated monoglyceride, colloidal silicon dioxide, and stearic acid. The tablet imprint contains iron oxide black ink. The inactive ingredients are colloidal silicon dioxide and stearic acid. The capsule and imprint contain titanium dioxide and indigo carmine ink.