We also have an interest in the relationship between nutrition and reproduction and investigate the molecular basis of leptin's action on the reproductive endocrine system. We use various animal models including the rat, mouse, various transgenically altered mice, and monkey, and we employ techniques including in situ hybridization, neuroanatomical mapping, gene cloning and targeting, and radioimmunoassays to explore these topics.
Serotonergic neurons are targets for leptin in the monkey.
Distribution of Galanin messenger RNA-expressing cells in murine brain and their regulation by leptin in regions of the hypothalamus. Perspectives on Leptin's Role as a Metabolic Signal for the Onset of Puberty. Galanin's functional significance in the regulation of the neuroendocrine reproductive axis of the monkey. Differential role of melanocortins in mediating leptin's central effect on feeding and reproduction .