They usually have more pockets and internal compartments than internal frame packs and items can be strapped onto the frame in the back. Generally, try to keep the heaviest part of your load centered close to your back and shoulder blades. Each person's center of gravity is different as is each packpack. How one person loads a backpack may not be ideal for another. Some women find that putting heavier items at the bottom of the pack is best for their balance simply because a woman's center of gravity tends to be lower than a man's.
Some backpacks designed for women ride lower, with the weight concentrated near their waist.
The sleeping bag rides on top of the pack on some of these packs. Experiment to see what works best for you. Do all bathing, clothes washing and pot scrubbing well back from the shores of lakes and streams. Prevent pollution by keeping soap and detergent out of all waters. Well, first, you can't worry about staying too clean out on the trail.