A randomized controlled trial. Infants seen by the health visitor nurses, who fulfilled the diagnostic criteria for infantile colic. One group received spinal manipulation for 2 weeks, the other was treated with the drug dimethicone for 2 weeks. Changes in daily hours of crying as registered in a colic diary. From trial day 5 onward the manipulation group did significantly better that the dimethicone group.
Spinal manipulation is effective in relieving infantile colic.