Dr. David Biller of Kansas State University has recently completed studies and published results showing PKD to be an Autosomal Dominant inherited trait. Published results are in the Journal of Heredity. As a quick review of genetics, an autosomal dominant gene is one which shows itself if it is present, even if inherited only from one parent. This means that a PKD free cat is also genetically PKD free. There is no specific treatment for this disease.
Treatment is similar to treatment of chronic kidney failure of any cause.
This treatment includes moderate dietary protein restriction using high biological value protein, dietary phosphorus restriction, providing fresh drinking water at all times, use of phosphate binders, and treatment of the anemia if necessary. Much more work needs to be done on polycystic kidney disease in cats to understand its underlying causes and devise effective treatment strategies. As PKD is the result of an autosomal dominant gene, it is relatively easy to track and eliminate. All breeding animals need to have an ultrasound to detect the presence of kidney cysts. It takes a few minutes with little or no sedation needed.