Precise monitoring of pH shifts may provide fundamental information on certain aspects of corneal metabolism, physiology, and morphology. Therefore, pH measurements may provide information on the etiology of these changes as well as methods to clinically monitor the changes. These studies concentrate on obtaining more fundamental information about the ocular response to extended wear of contact lenses. We have obtained considerable knowledge about the types and ranges of responses, and important information on the etiology and clinical management of some of these corneal changes. Clinical assessment of corneal hydration control in Fuchs' Dystrophy.
Stromal acidosis affects corneal hydration control.
Stromal acidosis modulates corneal swelling.