Matrix seems to act as an inhibitor in people who do not develop stones. However, in patients who suffer from stones, matrix appears to initiate and possibly provide the chemical framework upon which crystals develop. There are three primary types of hypercalciuria. The dissolved tissue creates excessive calcium in the blood that accumulates in the kidneys and produces calcium stones. Treatment of Hypercalciuria Resorptive hypercalciuria produces recurrent stone formation regardless of dietary restriction.
Treatment consists of treating the underlying disorder that produces bone resorption.
Absorptive Hypercalciuria Absorptive hypercalciuria is the most common form and is found in more than one-half of patients with stones. It results from an excessive intestinal response to vitamin D, causing the absorption of too much calcium from ingested foods. The diuretic furosemide, antacids, and steroids, can produce absorptive hypercalciuria. Treatment of Absorptive Hypercalciuria Diet and Hydration - Patients with absorptive hypercalciuria usually are placed on diets that restrict calcium and sodium. They are encouraged to add cereal bran to their diet because bran binds calcium in the gastrointestinal tract and helps excrete it from the body.