A live hungry adult mouse left in the cage with any captive python may attack and damage or even kill the python. Shedding Freckled pythons generally have few problems shedding their skin. When a snake incompletely sheds, and a portion of the skin is left adhered to the snake, the snake should be soaked in pure or slightly-soapy shallow water for several hours, after which the adhered shed typically comes off very easily. Small patches of skin that remain adhered to the snake are not expected to have any deleterious effect and it is at the option of the keeper to arrange for the removal. It's probably best to see that skin is not left on the face and eyes.
Some hatchling freckled pythons are ferociously nippy for the first few months of their life.
Not to worry. The snakes are small and the bites are harmless. Feed them lots of food and get them growing. Once they're about 4-6 months old, they begin to settle down. Adults are typically very good-natured.