The pattern of this illness establishes itself very early, although there are some fluctuations. Most people with the syndrome do eventually get better, and we have not seen anyone deteriorate to a more physically devastating, or terminal, illness. I think I have the syndrome. There is no definitive blood test or other diagnostic test. Rheumatologists, immunologists, specialists in infectious diseases, psychologists and allergists all have their own interpretations, but the facts aren't all in yet, and we have no objective test.
Some patients do have palpitations.
But we don't find that the palpitations typically require antiarrhythmic drugs or other medication. To answer the second part of your question, many people with the syndrome complain of running higher or lower temperatures than normal. As part of our acyclovir study, we took thousands of measurements of body temperature and found no significant abnormalities. A. Shortness of breath can occur in anyone who is severely deconditioned and then tries to do even light exercise. But abnormal lung function or low concentration of oxygen in the blood at rest are not a feature of the syndrome.