She s working under the direction of Shyamal K. Majumdar, Lafayette s Marshall R. Metzgar Professor of Biology and department head.
Tumors are fast-growing, they demand lots of energy to keep growing.
If you inhibit the blood that feeds the tumor, the tumor undergoes apoptosis, or programmed cell death. Ruddy is using three techniques to determine the effects of fumigillin on cell proliferation in two cancer-cell lines, Majumdar says. One is HeLa, a human cervical-cancer cell line. The other is murine erythroleukemic, or BB-88, a line of virally transformed mouse erythroleukemic cells. She is extremely bright, competent, and reliable.