HHNS DKA HHNS Typically affects people with Type 1 diabetes Typically affects people with Type 2 diabetes Insulin deficit rapidly decreases glucose use in the cells, so glucose remains in the bloodstream. Decreased insulin gradually decreases glucose use in the cells, so glucose remains in the bloodstream. Liver converts glycogen to glucose. Liver converts glycogen to glucose. Protein breakdown increases serum urea level.
Urea level is elevated due to dehydration.
Fat breakdown triggers ketone release, ketoacidosis. Arterial pH is normal or slightly decreased. Blood and urine are negative for ketones.