Both make such huge demands on your time and psyche. Without good, full-time child care, the two are almost irreconcilable. The combination is especially tough on women. Research shows that women entrepreneurs invest far more time in child care and domestic life than male entrepreneurs with similar responsibilities. Probably your first step is to ask yourself if that's a realistic goal.
Toddlers sense when their mothers are in crisis and become even more demanding.
Something has to give here. Next, pace yourself. Thought at a Time. Don't relinquish that. If you're running on empty hour after hour, you can't do your best work.