Students should then show and explain the structure displayed by them to the neighboring team. The carbon skeletons of deaminated amino acids can be catabolized for energy or used to synthesize glucose or fatty acids for energy storage. Only a few amino acids can be deaminated directly. Glutamate Dehydrogenase catalyzes a major reaction that accomplishes net removal of N from the amino acid pool . O 2 Most terrestrial land animals convert excess nitrogen to urea , a compound less toxic than ammonia, prior to excreting it.
Urea Cycle occurs mainly in liver .
The Carbamoyl Phosphate Synthase reaction proceeds in three steps, via carbonyl phosphate and carbamate intermediates, as shown at right. Carbamoyl Phosphate Synthase is the committed step of the Urea Cycle, and is subject to regulation. The Urea Cycle is summarized in the diagram at right and on p. 621 . Argininosuccinate Synthase 3. Given the localization of enzymes, for each cycle citrulline must leave the mitochondria, and ornithine must enter the mitochondrial matrix.