To be effective against KS, alpha interferon has to be given intramuscularly in high doses. Alpha-interferon works best if you have a T4 cell count over 400, no prior opportunistic infections, and you do not have symptoms such as fever, night sweats, and weight loss. Alpha interferon may be effective in eliminating or controlling chronic hepatitis B infection. Nausea is common.
Side effects get worse with higher doses.
Dosage Alpha-interferon is given by injection under the skin. For controlling chronic hepatitis B infection, injections of 3 to 5 million units are given three times per week. How long it may take to work Resolution of symptoms indicates that treatment is effective. Managing side effects Side effects diminish over time and it s important to hang in through the initial fatigue and flu-like symptoms and remember it will get better. Visible improvement of KS takes many weeks and improvement can continue over many months.