While investigating the cause, anti-histamines are prescribed for symptomatic relief. Antihistamines, when taken orally, take about 90 minutes to relieve an already formed hive. They work best if taken on a regular basic to prevent the formation of hives. Antihistamine creams are ineffective. Elimination diets are not helpful unless a particular food is suspected.
Skin tests are generally of no use.
Blood and urine test are sometimes carried out to exclude infection as a cause of chronic urticaria.