It is important to understand exactly which medication is being prescribed. Physicians prescribing progesterone have several dosage forms to choose between. The tablet produces consistent blood levels, which is critical for symptom management in PMS or menopause, and to avoid drowsiness, erratic menstrual cycles or breakthrough bleeding. Physicians often start patients out on rectal suspension because it allows them to titrate the dose to each woman s needs. The liquid suspension is administered rectally using a small syringe with applicator.
Suppositories also provide consistent, even absorption.
When used vaginally, many women complain of leakage that occurs. When used rectally, some patients report bowel stimulation. To Remember Patients and physicians should keep in mind that progesterone replacement therapy must be individualized for each patient. For cycling women, typical recommended dosing is two times per day, days 14-28, based on a 28 day cycle. For women no longer cycling or post-hysterectomy, dosing is daily.