It is sometimes found unexpectedly found by a routine blood count. However, there may be unexpected weight loss, spleen enlargement, sweating or bleeding. Some CMLs are associated with an abnormal chromosome called Philadelphia, although this abnormality is genetic, it is not inherited. CML has three different periods. The chronic phase averages 3 years but can be up to 10 or more.
Treatment involves chemotherapy such as hydroxyurea, or interferon.
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