The secrete to this agent is understanding how to control it. RNA virus, family Coronaviridae, Genus Coronavirus. Mice are susceptible to experimental infection, but natural infection has not been reported for this species. SDAV is one of the most common viruses in laboratory rats. It is highly contagious, spreading rapidly within rooms of susceptible rats by contact and aerosol.
Transmission is primarily by infected nasal secretions or saliva.
It is not transmitted vertically. The virus is present in tissues of infected rats for only about 7 days, and there is no carrier state. Less susceptible rat strains include WI, SD, LE, and F344. Occasionally, exudate causes the eyelids to adhere together. Signs of this form of disease usually are mild and subtle, escaping detection by most observers.