Cefmetazole is needed for Bacteroides fragilis coverage if the uterus may be contaminated by vaginal contents. For penicillin allergic patients. Some clinicians use clindamycin in penicillin- allergic patients. Hip fractures have a high incidence of morbidity with wound infections. Use vancomycin only for severe penicillin allergy.
Some clinicians use clindamycin in penicillin- allergic patients.
The most important measure for prevention of sepsis secondary to TURP is assuring that urine is sterile at the time of surgery. If urine is sterile the role of perioperative prophylaxis is probably of marginal benefit. Continuing antibiotic prophylaxis post TURP is strongly discouraged and will greatly increase the risk of nosocomial UTI with enterococci, resistant gram-negative bacilli, and candida. Organisms may vary depending on source of injury. If wound has been massively contaminated by soil, manure or dirty water, a regimen with activity against P. aeruginosa, S. aureus , and other gram-negative bacilli is recommended.