Our research laboratory investigates nucleocytoplasmic transport of macromolecules across the nuclear pore complex. Saccharomyces cerevisiae as a model organism.
Transport is mediated by specific shuttling receptors which belong to the importin beta superfamily.
Several export routes and NLS-independent import pathways have been identified recently. We apply a combination of molecular biology, genetics, biochemistry and cell biology techniques. Rahmen einer Diplomarbeit zu bearbeiten. The GFP fusion protein is concentrated at the nuclear envelope. Findling Tagesspiegel 2.