All of these findings are consistent with a hemolytic episode. Immune thrombocytopenia purpura generally lacks anemia and is dominated by petechial lesions and mucosal hemorrhage. Characteristic laboratory findings in PNH are anemia, leukopenia, and thrombocytopenia, also known as pancytopenia. Also, in DIC the fibrinogen is usually decreased. The presence of this fragment is an indication of fibrin clot formation and secondary clot lysis.
Thrombin time is usually prolonged.
Plasminogen is the inactive precursor of plasmin. Plasminogen may be depressed as the result of ongoing fibrinolysis. Clinical hematology and fundamentals of hemostasis. Diagnosis A diagnosis of TTP was made based on the patient's clinical presentation and the supportive laboratory data. Patients with TTP initially present with nonspecific symptoms of malaise, weakness, and fatigue.