Align screens first then use the micro Align the screens as close as you can first and clamp them down tightly. Next, use the micro adjust to fine-tune them. If the micros have been centered you have a fair amount of movement each way to bring the job into register. Double check the screens after registering them On some presses the screen arm will shift slightly when the screen is brought up and down. After you have a screen set-up, bring it up and down a couple of times to see where it will sit when you are doing the actual printing.
Some presses have a fairly weak center arm that allows downward deflection when the print is made.
This can cause a design to print slightly off register if you apply too much squeegee pressure that in turn deflects the arm. If this seems confusing just bring a screen down on the board and lean on the arm to see what happens to the registration of the print. The more the shirtboards get covered with lint and spray, the more imperfections you get in the prints. Clean your boards often with a little paint thinner and a scraper. Have all the tools at hand Get ready to make the print and get the job done.