Muscle movement occurs on both sides, i.e., both legs move during the clonic phase. Consciousness may be impaired. Generalized Tonic-clonic Seizures Formerly called Grand Mal. The first part of the seizure is the tonic phase, during which there is sustained contraction of all muscles. The second phase is the clonic phase during which there is rythmic contraction of muscles which is manifested as paddling or jerking of the limbs and chewing movements.
Some animals suffer milder generalized tonic-clonic seizures in which consciousness is maintained.
Grain A unit of measure which is approximately 65 mg. Some pharmaceutical companies distribute Phenobarbital using Grains instead of milligrams. A term which was used in the past to describe a generalized tonic-clonic seizure. The time it takes for one half of the original dose of a medication to leave the body. Hepatic Of, relating to, affecting, associated with, supplying or draining the liver.