The litter box is a place of refuge and contentment for your rabbit. They love to lie in them, roll over and snooze. It is vital to their health that this container be kept clean and changed as frequently as is needed. Please stay away from any litterbox fillers that contain cedar oil or are comprised of wood. Also, when they ingest the clay litter itself, it can adversely affect their gastro-intestinal tract.
Wood shavings react with the rabbit's urine to create a toxin which can build up in their liver.
If the rabbit needed to undergo surgery, their chances of recovering from the anesthesia are very much compromised. Vinegar is the only cleaner that you will need for your rabbit. Simply mix in a spray bottle one-half cup of white vinegar and fill the rest of the bottle with water. The vinegar neutralizes the ammonia in the rabbit urine. You can also pour a little vinegar in the rabbit's litter box when your rinse it out.