Every person needs to be evaluated on an individual basis. Risk in each person varies and you will need to discuss this with your doctor. Some studies have noted an increased risk, while others have found an increase in certain types of breast cancer. You need to discuss this issue with your physician. Additionally, every woman on estrogen or hormone replacement should undergo periodic breast self examinations and mammograms as determined by her physician.
Skin absorption bypasses the liver circulation and is more easily titrated.
You would need to discuss this with your physician. Estrogen keeps bones healthy and prevents osteoporosis. It may also be helpful with cardiovascular diseases, although studies in this area are less unanimous. Several large, prospective studies have yielded varying results, including increased risk for certain kinds of breast cancer, although some studies found that the total risk for breast cancer of all kinds may not be increased. This is an area that you would need to discuss carefully with your physician.