This sets the stage for the development of diabetes, hypertension, and heart problems. The body has an almost limitless capacity to store fat. Not only can each fat cell balloon to more than 10 times its original size, but should the available cells get filled to the brim, new ones will propagate. As the body stores more fat, weight and girth increase. A number of studies show that genetics may be the most important determinant of how much you weigh.
Some people are more prone to weight gain than others are even when caloric intake is the same.
Research indicates that obesity may be linked to the proportion of fat in the diet rather than to the amount of calories consumed. It is likely that a number of genetic mechanisms exert influence on weight, among them genes that dictate metabolism and appetite. If too much LPL is produced, the body will be especially efficient at storing calories. In women, fat cells in the hips, thighs, and breasts secrete LPL, while in men the enzyme is produced by fat cells in the midriff region. Fat cells in the abdominal area release their contents for quick energy, while fat in the thighs and buttocks is used for long-term energy storage.