If an antidepressant is prescribed, it is important to take it exactly as prescribed. Counseling and support groups may be helpful. Feelings of rage may occur in some patients on interferon. If feelings of rage occur, the treating provider should be notified. Tearfulness and wide swings of emotion may occur within the first few weeks on interferon.
Some people describe laughing or crying spells that are out of proportion to the stimulus.
This may or may not resolve without intervention. The treating provider should be informed if tearfulness or mood swings occur. Mental confusion is especially common within the first few weeks of interferon therapy. Increased intake of water, juices, sports drinks and non-caffeinated fluids may help reduce this side effect. Decreased concentration is especially common within the first few weeks of interferon therapy.