The dose must be adjusted carefully depending on the age and size of the child. When you are taking medicine for pain, ask your doctor, nurse, or pharmacist about taking any other medications. However, some combination cold medicines contain pain relievers and it may be necessary to lower the dose of your pain medicine. Many combination medicines for colds, menstrual pain, headaches, and joint or muscle aches contain aspirin. Cancer patients are usually told to avoid aspirin, especially if they recently have been on chemotherapy.
Some pain medicine can also cause sleepiness.
Taking them together can make it dangerous to drive or to operate machinery. Before you take any nonprescription medicine, it's a good idea to read the label and seek the advice of a health professional if there's anything you don't understand.