The Lloqueta is a small river in the Andes Mountains. Its watershed covers an area of about 100 square kilometers at altitudes up to 5300 meters. The Lloqueta lies within the Cadena de condos volcanicos part of the high Puna plateau. While the Andes are dominantly compressive, this area is characterised by neutral or extensional stresses. Soils within the valley are primarily alluvium and colluvium originating from late Cretaceous to early Tertiary volcanic rocks.
Vegetation cover is sparse, with only short grasses and mosses lying near drainage channels.
Land use in the Rio Lloqueta basin is seasonal and limited to grazing alpacas and llamas on the grasses near the quebradas. During the dry season herders occupy six remote estancias in the basin, and the animals are corralled at the estancias during the night. The pass above the Lloqueta is used as a trade route between Cailloma, a mining center to the north, and Lari, a pueblo in the Rio Colca valley. The search for the most distant extent of the Amazon river system has been a subject of interest for centuries. The first published discussion of the source of the Rio Amazonas appears in 1641.