PCP can trigger psychosis in people with no previous history of mental illness, leading to accidents, suicides and violence. This inaccuracy often leads to overdose. Some people store PCP in fatty tissue, where it can be released months or even years later, causing actual chemical flashbacks. In the event of PCP overdose, users require immediate medical attention. Included in this group are the drugs MDA, MDMA, PMA and ketamine.
Some users report a sense of peacefulness.
Heavy use of MDMA causes a prolonged increase in body temperature and dehydration. Users have also experienced severe depression and feelings of suicide after this drug's effects subside. MDMA impacts dopamine production, which can lead to motor coordination disturbances. PMA strongly stimulates the CNS, and at higher doses can lead to convulsions, coma and death. Ketamine was developed primarily for use in veterinary medicine, though it is also used as a pain killer in humans.