Recent work in our lab has documented that this response occurs on a cellular level under in vitro conditions. The impact of PGS on the cytoskeleton of GI cells has not been fully elaborated. A rotation in this laboratory would examine these issues by exploring the effects of PGS on cellular microtubules, actin and intermediate filaments. The student will be exposed to standard immunohistocytochemistry and advanced microscope techniques including epifluorescent microscopy and confocal laser imaging microscopy.
Time is variable.
All work to be conducted in the Surgical Research Institute or Pediatric Research Institute.