We have substituted the use of 7 day Streamline Catheters instead of pic lines or midline catheters. This has greatly reduced the cost and risks associated with these types of catheters. After three infusion rounds, three of the five participants have seen dramatic increases of CD-4 counts at the 12 day after infusion point. It is too soon to comment of the functionality of the cells. Based on this small group of highly motivated patients, CIV infusion therapy with IL-2 is possible, and safe to do on an out patient basis.
Side effects are manageable.
Most of the cost is attributable to the IL-2.