It is the most serious of the upper respiratory diseases in cats, and, in advanced stages, produces a discharge from both the eyes and nose. Rhinotracheitis can be fatal to kittens and can become chronic. Signs of infection are similar, but cats with calicivirus may also have ulcers on the tongue. Death is uncommon. Signs are similar to rhinotracheitis and calicivirus.
Symptoms sometimes appear in only one eye.
Infection can be transient and recoverable or permanent and fatal, depending on the situation. Signs of possible infection are continuing poor health or frequent illness or fever. Feline leukemia virus, as its name suggests, can also cause leukemia and other cancers of white blood cells. Clinical signs may include fever, weight loss , poor appetite or a swollen abdomen. Vaccination is done through nose drops instead of shots, targeting the initial replication site of the virus.