The ScanArray 3000 is a confocal laser scanner designed specifically to detect signals from dual fluorescent-labeled microarrays. Image processing and signal analysis are performed using the software package ArrayVision . The array images typically require little image processing, only basic image processing techniques are applied, such as gamma curve correction. The first step in analyzing the signal intensities is constructing a measuring grid. After a rough grid is constructed, ArrayVision performs a spot by spot alignment of the grid to the array.
Some manual alignment is necessary for spots with low intensity values.
After the grid has been constructed and properly aligned sample signals are measured and displayed. One of the main goal of our lab is to make widely available the genomic technologies and resources that we develop. Our relational database, GenMapDB, consists of a lab management component and an external component that is freely available to everyone. The lab component of the database is designed to allow lab members to track and manage data from their experiments. The external component provides information such as the genomic locations of all the mapped clones, BAC end sequences and HindIII fingerprints.