Therapy involves reversing the initial insult. Infectious agents are common problems, especially venereal diseases. Brucellosis is a venereal disease that causes epididymitis, orchitis and azoospermia. Brucellosis is primarily a problem in cattle, sheep and dogs and usually requires euthanizing affected animals. Other bacterial infections are common in stallions and stud dogs.
Therapy is as indicated by the culture and sensitivity.
Neoplasms are rare in domestic animals except in the dog where Sertoli cell tumors and seminomas are seen. In older stud dogs, prostatic tumors are fairly common. Therapy of prostatitis, prostatic hyperplasia and prostatitic neoplasia are antibiotics, castration, and ablation, respectively. Trauma is a common problem, especially in the herd situation. This is easy to diagnose clinically and therapy involves surgical intervention or medical therapy.