Compared to mucous cells, serous cells have a greater ability to concentrate the 131 I. Consequently, the serous parotid gland will demonstrate a more intense radiation sialadenitis than the mucous cell-containing salivary glands. Obviously, the effect is dose related. Regardless, manifestations of injury may become apparent in succeeding cell generations with severe objective and subjective symptoms evolving. Persistent sialadenitis is not an unexpected complication. I injury, may be unilateral or bilateral.
Salivary volume decreases.
Permanent xerostomia with a caries increase can occur. Infection ensues from an ascending ductal infection facilitated by a diminished ductal ravage and an impaired gland. A small increase in salivary tumors has also been reported. Artificial saliva has not met with patient satisfaction. Aggressive fluoride therapy and oral hygiene impede caries from salivary loss.