Epidermis and dermis. The enzimatic activity of skin is localized in the stratum granulosum which seems marked by a continuous red-brown strip. That means that th ese cells have a great production of enzyme, even if they are in their penultimate phase of life. All nucleous are stained by methil green. 1995 Vevy Europe Photoimage Skin of a 50 years old man.
Skin fold in clavear area.
Many melanocytes full of melaninic granules are disposed along the basal membrane. The presence of esterasic enzymes in the cells of the stratum granulosum is connected with their process of keratinization. 1995 Vevy Europe Photoimage Skin of a 50 years old man. Cutaneous crest, it is evident the positivity of the stratum granulosum. The layers below are not reactive for this enzyme and the stratum corneum not even.