You can use tables to organize your material. In particular, you can use tables to put material into columns, lists or boxes without using frames. This lets you present clear pages that load quickly. The UT Homepage is a great example of the use of tables to organize content. You can also put tables within tables.
Tables can also have their own background color or images.
Because FrontPage has its own quirks, use the Help system. Back to contents. There has been a lot written on this point, so I'll be brief. Assume your audience will skim or scan your document. Think in terms of good newspaper or advertising design.