Anything that contradicts that must be viewed as false. Such makes no sense whatever. It is entirely inconsistent. It hardly goes without saying that countries who have adopted this mode of thinking generally are some of the most disadvantaged in the world. According to the biblical record, this is because there is a divine law from God, and the breaking of that law is an act of spiritual criminality.
Sin is demonstrated in a variety of ways.
Man is totally without the ability to provide a remedy for his sin. He is, therefore, desperately in need of a Savior. In contradistinction, Eastern thought does not see man as one who has departed from his Maker. Karma is thus viewed as neither good nor bad. It simply is.