Ribosome reaches stop codon and releases polypeptide. Signal Sequence binds to translocon. Some components same as co-translational translocon. BiP is important in translocation. Cleaves signal sequence during translocation. - Oligosaccharyltransferase.
Transfers sugars to the protein during translocation.
Its a chaperone. Usually have a transmembrane domain, inserted into lipid bilayer. Orientation determined by transmembrane domain Questions 1. Describe the mechanism of co-translational translocation of ER proteins.