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Some drugs are hepatically metabolized and possess a high extraction ratio.
D only 5. A loading dose of 300 mg is administered over 30 minutes. 3.50 hours 4. 6.00 hours 5. Gentamicin pharmacokinetics can be described using a 1 compartment model, undergoes first order metabolism, and is entirely cleared from the body unchanged by the kidneys. D only 5.