The side effects reported tended to be mild. Gastrointestinal irritations accounted for 0.6 percent, allergic reactions for 0.5 percent, tiredness for 0.4 percent, and restlessness for 0.3 percent. Hypericum's side effects went away soon after the patients stopped taking it. If you are having suicidal thoughts, and you think you even may act upon them, please get emergency medical help at once. Call a suicide hotline, your physician, your therapist, your religious counselor, or 911.
Suicidal thoughts are a natural part of depression.
Any plan to act on these thoughts is a danger signal that you must get help at once. If you are taking prescription antidepressants, do not alter your dosage or combine with hypericum without first consulting your doctor. Do not take hypericum if you are taking an MAO inhibitor. If you have a preexisting medical or psychiatric condition, please consult your doctor before taking hypericum. If you are taking an oral contraceptive or medication to treat HIV, be aware that your medication's effectiveness may be significantly reduced.