Influenza, common cold, low back and neck pain, dysmenorrhea, headache, toothache, sprains and strains, fractures, myositis, neuralgia, synovitis, arthritis, bursitis, burns, injuries, following surgical and dental procedures. Patients who had a bronchospastic reaction to ASA or nonsteroidal anti-inflammatory drugs. Today, ASA is one of the most frequent causes of accidental poisoning in toddlers and infants. ASA containing preparations should therefore be kept well out of the reach of all children. Salicylates should be administered with caution to patients with asthma and other allergic conditions, with bleeding tendencies, or with hypoprothrombinemia.
Salicylates can produce changes in the thyroid function tests.
ASA has been found to delay parturition in rats. This effect has also been described with nonsteroidal anti-inflammatory agents which inhibit prostaglandin synthesis. Because of possible adverse effects on the neonate and the potential for increased maternal blood loss, ASA should be avoided during the last 3 months of pregnancy. Although a direct causal relationship has not been established, it is recommended that salicylates be avoided when possible in children, teenagers and young adults with influenza or varicella until the nature of the possible association between ASA and Reye's Syndrome has been clarified. Salicylates increase the effects of oral anticoagulants.