No further evaluation is required if renal function begins to improve within several days. Glomeruli usually are normal. The earliest finding is interstitial edema, typically followed by interstitial infiltration with lymphocytes, plasma cells, eosinophils, and few PMNs. The presence of noncaseating granulomas suggests sarcoidosis. Immunofluorescence or electron microscopy seldom reveals any pathognomonic changes.
Treatment is recommended for severe prolonged oliguria.
Recovery, however, may be incomplete, with persistent azotemia above baseline. All rights reserved.