The classification of transgenic tumors. The mammary tumors in transgenic mice are unique. Each transgene is associated with a different identifiable type of tumor. Back to Index 6. Neoplastic progression in PyV-MT transgenic tumors.
Some transgenic lines have a very high rate of metastasis.
The animals with the Polyoma Virus Middle T transgene form tumors and have pulmonary metastases within 6 weeks of birth. Back to Index 7. Angiogenesis in transgenic mammary tumors. Transplants of PyV-MT tumors result in very angiogenic tumors. The complexity of the microcirculation correlates to the ability to metastasize.