In contact with the human skin, these caterpillars produce a burning similar to that produced by any other caterpillar. From 2 to 72 h after the burning, hematomas, ecchymosis, hematuria, gingival bleeding, headache and pallor appear. Lonomia venom is believed to have fibrinolytic action, as well as an action similar to disseminated intravascular coagulation. Consumption of coagulation factors and acute renal failure begin as a complication of hemorrhagic problems. Osteoarticular manifestations occur mainly among rubber tappers in the Amazon region as they touch caterpillars of the genus Premolis .
Skin reaction consists of pain, itching and erythema.
Subsequent and continuous accidents lead to chronic deforming arthritis. Anesthetic blockade as well as application of local heat greatly reduce clinical symptoms. Systemic analgesics, antiinflammatories and corticosteroids help relieve pain and inflammation. Patients with hemorrhagic syndrome must be hospitalized. They should receive replacement of fresh plasma, blood derivatives and special attention to internal hemorrhage.