The average observation time after the therapy was 83 month, with the maximum being 146 months. Complete remission was included in 5 patients, partial remission in 27, and no change in 12. Operations, selected by the results of the preoperative therapy, included transurethral resection on 28 patients, transurethral fulguration on 2, partial cystectomy on 4, resection of tumor on 4, and total cystectomy on 3. Operations were not performed on 2 patients and not allowed on 1 patient. We concluded that preoperative chemotherapy combined with radiation therapy may be effective for the treatment of bladder cancer.
Tumors can occur along the surface of the bladder or grow within the bladder.
Bladder cancer is more common in men than in women and occurs most frequently in people over 50. It has been highly associated with cigarette smoking and chronic bladder irritation and infections. These occupations include rubber workers, aniline dye workers, hair dressers, and petroleum workers. The first sign of bladder cancer may include blood or pus in the urine, painful and frequent urination, and possibly a burning sensation when urinating. A late sign may be a large mass felt upon examination.