MSM has a significance, because sulfur compounds are found everywhere throughout the body and in nature. Sulfur has an indirect importance, because sulfur compounds play a role in many body organs and systems. Sulfur is in the hair, skin, and nails. Many amino acids, the building blocks of protein, have sulfur as a component. Many B-complex vitamins interact with or contain sulfur.
Sulfur is needed for insulin production.
One current use of MSM is for joint problems, as sulfur is found in and near osseous structures. Sulfur supports healthy muscles, tendons, and ligaments. MSM normalizes pressure inside cells and removes toxins. Oregon Health Sciences University has conducted arthritis studies with mice. The other non-MSM mice had cartilaginous degeneration.