Sandhoff disease is a rare, genetic, lipid storage disorder resulting in the progressive deterioration of the central nervous system. Onset of the disorder usually occurs at 6 months of age. There is no specific treatment for Sandhoff disease.
Treatment is symptomatic and supportive.
The prognosis for individuals with Sandhoff disease is poor. Death usually occurs by age 3 and is generally caused by respiratory infections. The goals of this research are to increase scientific understanding of these disorders, and to find ways to prevent, treat, and, ultimately, cure them. The Neurological Disorders, vol. II, 2nd edition, Butterworth-Heinemann, Boston, pp.