Spraying the outside foundation and the soil next to it with diazinon insecticide may keep unwanted invaders out. Be sure to read and follow all label directions. Once in the home most spiders can be scooped up and gently deposited outdoors by the designated spider remover. Or can be removed by vacuuming. Also move and dust often behind and under furniture, stored materials, wall hangings and ceiling corners to discourage spider establishment.
Spiders are good guys.