What the world is made of isn't really all that important to science. I do not think that science will disprove God by setting limits on the material that exists in the universe. If there were a danger, it would be that mechanism would so triumph that God would truly become irrelevant. The new material is inevitably introduced as an attempt at mechanism. On the otherhand, fantasy does not need to introduce mechanism.
Science is in the business of demystifying the universe.
The means is to introduce mechanism to explain what is observed. Material is often brought into existence to provide the mechanism. Reality is fleeting at the quantum level, but science isn't troubled. Reality for science consists of mechanism, not material. The faith of science is that even where it isn't seen, mechanism exists.