3.Death results from volume depletion, electrolyte imbalance, infection, and cardiac arrhythmias. 4.Treatment is best carried out in an intensive care unit if available. Intravenous dextrose and saline should be given at a rate adequate to replace fluid losses and maintain blood pressure. In cases of circulatory collapse, pressors may be needed. F. c. Parenteral thiamine 100 mg per day should be continued at least until normal diet is resumed.
Sedation helps diminish autonomic symptoms and agitation.
Parenteral administration is best because most patients would not be able to take anything by mouth. Diazepam 5 to 10 mg intravenously can be given every 15 to 20 minutes until sedation is achieved. Repeat doses should be given as needed. All severely agitated or combative patients should be restrained. Restraint should be carefully managed in order to avoid decubitus ulcers and nerve compression or traction injuries.