Driving from San Diego and Mexico, I-5 is the obvious choice. As in the rest of the US, driving is done on the right. A free bus runs between the terminals and deposits you at the LAX Transit Center, where you can swap to a city bus. Free shuttles also run to the Metro Green Line Aviation Station, where you can catch a train headed in the direction of Redondo or Norwalk. You can also try one of the many car rental agencies at the airport, where rates are the most competitive in town.
Taxis are convenient but expensive.
Shuttles, limos and taxis serve the area's other airports. In addition, the Burbank Airport has Metro and Amtrak connections. You can find several major car rental agencies at all the region's airports. Although LA is definitely built for cars, it is possible to get around on public transport. Metro Rail trains run between downtown and Long Beach, Union Station and Western Ave, and Norwalk and Redondo Beach.