This was determined using antisense oligonucleotides directed against notch and a retrovirus vector transducing activated notch in vivo. In a parallel approach, cDNA libraries have been constructed from the retina at different points in the developmental program. They are being screened by polymerase chain reaction and by using hybridization with a variety of probes from other systems. Many novel and known receptor tyrosine kinases have also been identified. Altshuler, D., Lo Turco, J., Rush, J. and Cepko, C. L. 1993.
Taurine promotes the differentiation of a vertebrate retinal cell type in vivo.
Walsh, C. and C.L. Cepko. Cell lineage defined by a retroviral library method does not specify functional neocortical areas. Nirenberg,S. and C.L. Cepko. 1993. Targeted ablation of diverse cell classes in the nervous system in vivo. Austin, C. A., Feldman, D., Ida, J., and Cepko, C.L. 1995.