Usually it occurs in children younger than 2 years old and in elderly patients and commonly in the first 6 months of the treatment. If these symptoms occur, contact your doctor immediately. Depakote can reduce the body's ability to manufacture certain blood cells which are important to fight infections and prevent bleeding. A reduction in these cells can cause fever, sore throat and ulcers in the mouth, or unusual bleeding and easy bruising. If these symptoms occur, contact your doctor immediately.
Skin rash can occur.
Because rash can indicate a more serious medical condition, contact your doctor immediately if you develop a rash, fever, or swollen glands. This risk increases in women taking more than one anti-epileptic drug. Discuss this with your doctor. It is very important to take your medication regularly since a stable blood level helps to reduce seizures. Therefore, the medication does not work when taken on an as needed basis.