In children, the symptoms begin to be expressed by around 4 years old. Wilson's disease causes the body to absorb and retain excessive amounts of copper. The copper deposits in the liver, brain, kidneys, and the eyes. Eye movement may be restricted. Serum ceruloplasmin is low.
Urine copper is high.
CBC may show hemolytic anemia or decreased white blood cell count . Serum uric acid levels are low. A head MRI or head CT scan may be abnormal but nonspecific. An abdominal X-ray , abdominal MRI , or CT scan of the abdomen may indicate liver disease or other abnormality. A liver biopsy or biopsy of the kidneys or other suspect tissue shows deposits of copper, and shows tissue changes that indicate damage to the tissues.