Most studies use 500 mg of hydroxyurea taken twice a day. One study tried a lower dose of 500 mg once a day, and even this low dose seemed to help ddI work better than ddI alone. If side effects are a problem, the lower dose is worth considering. Resistance is not an issue with hydroxyurea, as it is with other anti-HIV drugs. Hydroxyurea as salvage therapy .
Salvage therapy is for someone who's used up all their treatment options.
Caution should be used in using hydroxyurea in people with advanced HIV, low T4 counts and extensive treatment history because of its toxicity. One person experienced bone marrow failure and there were two deaths. Hydroxyurea is available by prescription. This information does not intend to promote or endorse any specific treatment for any health related condition.