Therefore, independent investigations of these cells are necessary. . . . . Reliable methods for isolation and culture of normal uveal melanocytes and uveal melanoma cells have been established in the past decade. These cells produce melanin in vitro , and serve as a good model for studying melanogenesis. Several research centers in Europe and the United States are now working actively in this field. Communications among these groups is of paramount importance, as is the ability to communicate with researchers studying epidermal melanocytes and cutaneous melanoma who communicate regularly under the aegis of the International Federation of Pigment Cell Societies.
Uveal melanoma is the second most common melanoma observed in humans.