Jesus says that when we pick up the New Testament, God is speaking directly to us, to our generation and our time. When Jesus was on this earth, the earliest section of the Old Testament had been copied by hand and passed down from generation to generation for 1400 years. The Scriptures cannot be set aside by man, for they possess an authority so great that they cannot be broken, annulled or disregarded without consequence. This verse contradicts those who claim that Scriptures can be set aside if the situation demands it. Regardless of what man discovers, man will never discover a historical or scientific truth that will contradict what is found in Scripture.
Scripture never becomes irrelevant or out-dated.
Time and culture do not deprive Scripture of its authority. Every passage stands equally authoritative and equally inspired. We cannot pick and choose which Scriptures or doctrines we think are more important than others. Be impressed that Jesus is making a rather technical argument. God isn t against fine tuned arguments.