Bone collapse and even dislocation can then occur. This is seen most The initial pain pattern of a metastasis mimics that of primary bone cancer and osteonecrosis. The symptoms are intermittent but may be sharp and severe. Pain tends to be worst at night and maybe General systemic issues are of concern in patients with skeletal metastases. Bed rest or reduced activity is frequently recommended for the bone pain of skeletal metastases.
Symptomatic relief is usually satisfactory from radiation therapy and chemotherapy.
Most patients without a fracture do not require surgery for the bone cancer. Fractures are best treated by operative internal fixation. These lesions tended to occur late in the course of disease and were purely lytic. Multiple myeloma and breast and kidney cancers healed most frequently. These lesion often occurred early in the course of disease when patients had more therapeutic options available.