Symptoms are usually transient and only infrequently severe.
Consider prophylactic administration of atropine prior to subsequent doses of Camptosar at discretion of physician. 5 days Can be prolonged, may lead to dehydration and electrolyte imbalance, and can be life-threatening. Patient should also be instructed to notify the physician's office if diarrhea occurs. Carefully monitor patients with Grade 3 or 4 diarrhea. If patient becomes dehydrated, give fluid and electrolyte replacement.