Retin-A usually begins to clear up acne in two to three weeks, although in some cases it's more than six weeks before any improvement is noticed. Therefore, those who use Retin-A should stay out of the sun as much as possible, and when in the sun should minimize its effects with sunscreens and protective clothing. Retin-A users should also avoid sun lamps because their ultraviolet rays mimic those of the sun. Another common side effect of Retin-A is drying, irritation or peeling of the skin. When this occurs, the doctor may suggest patients cut back use to two or three times a week.
Some antibiotics are effective for treating and preventing pustules and cysts of severe acne.
Tetracyclines and erythromycin are the most commonly prescribed. Treating Severe Cystic Acne For very severe, disfiguring acne unresponsive to the treatments mentioned, the doctor may prescribe isotretinoin, commonly known as Accutane. A derivative, Accutane is taken orally in capsule form. It is highly effective for treating severe cystic acne and preventing the deep pits and scars that result. Scientists do not know exactly how Accutane works, but evidence suggests that it reduces the size of the sebaceous gland and the amount of sebum secreted.