If your stools become darker than normal or you notice unusual bruising, tell your doctor or nurse. These can be signs of internal bleeding. People rarely have any side effects from the usual dose of acetaminophen. How, ever, liver or kidney damage may result from using large doses of this drug every day for a long time or drinking large amounts of alcohol with the usual dose. Serious side effects from ibuprofen are uncommon.
Some people notice that it upsets the stomach.
When it is used for long periods of time or when it is used by patients taking steroid medications, there is an increased risk of stomach bleeding. If you have kidney problems, ibuprofen may make them worse. And, because it may interfere with the ability of blood to clot, it may be dangerous for patients with low platelet counts. The doses of these pain relievers are different for different people. Some people get the best pain relief when they take a small dose every 3 hours.