3TC is also available in Combivir and Trizivir. Trizivir contains AZT, 3TC, and abacavir. For more information, see Fact Sheet 426 on Combivir or Fact Sheet 427 on Trizivir . These side effects usually get better or disappear over time. The most common side effects of 3TC are nausea, vomiting, fatigue, and headaches.
Some people have trouble sleeping.
There have been rare cases of hair loss. 3TC is more effective if taken with other antiviral drugs. Blood levels of 3TC may be increased by bactrim or septra. See Fact Sheet 535 for more information on these drugs.