This data suggest slow absorption, low peak serum levels, and a long half-life. Currently research is focusing on letrazuril, an oral fluorine-based congener of diclazuril. In preclinical studies, the drug is more readily absorbed than diclazuril. Other Major Uses Veterinary uses, coccidiostat in poultry. New benzeacetonitrile with anticoccidial activity.
Treatment regimens for patients with toxoplasmic encephalitis.
Lemeteil D, Roussel F, Favennec L, Ballet JJ, Brasseur P. Assessment of candidate anticryptosporidial agents in an immunosuppressed rat model. A pre-clinical in vitro toxicological model using human lymphocytes. Soave R, Dieterich D, Kotler D, Gassyuk E, Tierney AR, Liebes L, Legendre R. Oral diclazuril therapy for cryptosporidiosis . Always watch for outdated information. This article first appeared in 1999.