Additionally, it has been reported that fumonisin toxicity in sensitive cells was prevented by IAP, an inhibitor of TNF a pathway. The TNF a can also stimulate cell proliferation in certain circumstances. We are therefore attempting to investigate the role TNF a plays in mediating the toxic effects of fumonisins. The downstream signaling processes involved in the TNF a -induced cellular operations are being investigated. It is expected that these investigations would provide the mechanisms involved in tissue and species variability observed in fumonisin toxicity.
Salary is competitive and commensurate with qualifications and experience.
Qualified candidates may be considered for non-tenure faculty positions at a later date. Candidates are encouraged to contact the undersigned with any questions. For examples of recent articles on this and other research projects from this laboratory, see details in the faculty listing of the undersigned in the Department of Physiology and Pharmacology.