It also has a tail that binds to one microtubule and two globular heads that climb the other microtubule. Many dyneins 'decorate' a microtubule and climb the other microtubule like a cat climbing a tree. Cytochalasin caps the positive end of microfilaments and therefore favors, forces disassembly into monomers. Microtubule function can be disrupted by colchicine and taxol , plant-derived toxins, which both work by inhibiting microtubule assembly. Colchicine at low concentrations can block depolymerization and at high concentrations can induce depolymerization.
Temperature can also affect polymerization dramatically.
At 4'C, microtubules depolymerize and at 37'C microtubules repolymerize. We've talked about the Central Dogma, alluded to the cell compartments and processes responsible for transcription and translation, and discussed many proteins involved in cell function. We will feature the immune system for this discussion and focus on the production of antibodies. These proteins are found in all chordates, from the shark to the human. B cells can be found resident in the lymph nodes , spleen and circulating through the body via the lymphatic system , and blood vessels .