The alternate aim would be to control the disease in those individuals who are particularly susceptible to severe infection eg. immunization against VZV in leukaemic children and the immunization against influenza in children with chronic diseases. The safety, efficacy, volatility and the cost of the vaccine should be assessed. Serious adverse effects, however rare, may discourage parents from taking their child for immunization eg. Live vaccines should not be given to immunocompromized individuals. For universal vaccination, the vaccine should be as effective as possible as it would be impractical to test each individual for seroconversion afterwards.
Some vaccines are less stable than others and require good cold storage facilities eg.
Inadequate refrigeration facilities are thought to be one of the causes of vaccine failure in the case of the Sabin polio vaccine in third world countries. Finally the cost of the vaccine and the cost of administering the whole program should be considered. Cost would be a far more important consideration in developing countries than developed countries. The following are common childhood viral diseases for which vaccines are available or being developed. Childhood rashes Measles is a potentially severe disease with severe complications.