Red wolves are not a threat to humans. A healthy wolf has never attacked a human in America. The red wolf is shy. They usually run away when sighted. Unless a person has a specific allergy, neither venom is life threatening.
Timber rattlers are more poisonous, but bites are rare since they rattles before attacking.
Copperhead bites occasionally occur, but the bite is mild. Both snakes are more active at night. To avoid these snakes stay on the trail and do not disturb wood or rock piles, stone fences, and old buildings. The most serious animal hazard is to people allergic to bees. If you have this condition, carry appropriate medication, and do not travel alone.