Berwick campus is about one hour's drive from Melbourne, in the south-east growth corridor of Victoria. The campus is adjacent to the railway station and within five minutes walk of the Berwick town centre. Caulfield campus is located on Dandenong Road about nine kilometres south-east of the city. This campus is a modern high-density campus and incorporates a shopping plaza. The campus is adjacent to the Caulfield railway station on the Frankston and Dandenong lines.
Trams run past the campus to the city and surrounding suburbs, and bus lines are nearby.
Clayton campus is Monash's original and largest campus, located about 20 kilometres south-east of the city. The campus is set in 100 hectares of parkland and is almost a city unto itself with on-campus cafes and bistros, a cinema, a post office, and shops including a general store, hairdresser, computer store, health food store, chemist, newsagency, banks, and an amusement arcade. Clayton campus has several bus services, most of which stop in the on-campus bus loop. The buses connect with the nearest railway stations - Clayton, Huntingdale, Syndal, Oakleigh and Ormond. Gippsland campus is located at Churchill in the Latrobe Valley about 168 kilometres east of Melbourne or about two hours along divided highway by car from the city.