Manuscripts reporting advances in basic biomedical science, especially in cell biology, molecular biology, genetics, pharmacology, immunology, and physiology, are welcome. We encourage submission of papers reporting discoveries that enhance understanding of the pathogenesis, etiology, natural history, underlying mechanisms, and molecular basis of disease, as well as studies that present innovative applications of new technologies, such as bioinformatics, pharmacogenetics, proteomics, functional imaging, and surrogate markers. Dose-escalation studies involving new drugs or efficacy studies of novel therapeutic agents, approaches, or interventions are of interest. We also invite scholarly papers discussing opportunities, challenges, and ethical issues related to basic science and translational research. We look forward to receiving manuscripts for consideration for publication in this theme issue.
Submitted manuscripts are subject to our usual rigorous editorial evaluation and peer review.
High-quality manuscripts not accepted by JAMA may, with the authors' permission, be referred to one of the Archives specialty journals for further consideration for publication. Authors are encouraged to consult the JAMA Instructions for Authors 6 for guidelines on manuscript preparation and submission. We welcome manuscripts on basic science and translational research in the spirit of advancing the best science into the best patient care. We look forward to sharing this experience and this important information with authors, readers, and the biomedical research and scientific community. Dr Fontanarosa is Executive Deputy Editor and Dr DeAngelis is Editor, JAMA .