The course is usually fluctuating and chronic, with worsening during stress. Consequently, the benzodiazepine should be tapered slowly rather than stopped abruptly, if it is to be discontinued. The relief obtained usually outweighs any mild adverse effects and the possibility of drug dependence. Buspirone is also effective for some patients, although its onset of effect takes about 2 wk, whereas benzodiazepines work within minutes. Buspirone does not cause dependency.
Some antidepressants are also effective.
The benefits of behavior therapy are limited because specifying anxiety triggers to which the person can be exposed is difficult. Relaxation and biofeedback may be of some help, although few studies have documented their efficacy. Insight-oriented psychotherapy has not been systematically studied in this disorder. All rights reserved.