When examined with a ophthalmoscope, the affected retina shows progressive thinning or atrophy, hence the name given to the disease. Some forms of PRA, such as that found in Irish Setters, develop very early and result in total blindness by 1 year of age. Late-onset PRA is found in Poodles, cocker Spaniels, Labrador Retrievers and other breeds. It was long thought that the form of PRA peculiar to Miniature Schnauzers is of the late-onset type but, as a result of research published in 1991, it is now believed that the PRA found in Miniature Schnauzers is actually an early onset disorder in which the clinical manifestations are uniquely delayed. The ophthalmoscopic hallmarks of PRA are not apparent until very much later in life and unlike other early-onset forms of PRA, visual function is only subtly affected in young affected animals.
Vision remains relatively normal for many months to years.
The American Miniature Schnauzer Club of American is funding research to isolate this gene which is being conducted at The Baker Institute at the College of Veterinary Medicine of Cornell University. Funds are need to continue this research. She slowly lost her sight from there over the next two years or so. Amy is loved by Rolf and Bobbi Baehr of Loveland, Colorado, USA who we express our appreciation for sharing Amy's photo with us.