Fingernails become thinner and more brittle. If exercise is not increased, some muscle tone is lost. Given a caloric intake and exercise regimen consistent with pre-hormonal treatment, one tends to gain weight, lose energy, need more sleep, and become cold more easily. Some middle-aged and older transsexuals who start or resume hormone therapy report improved memory and overall mental faculty. Internal emotions are amplified, becoming more apparent, distinguishable, and influential.
Some people report reduced anxiety and increased sense of well-being.
This could be a placebo effect. This observation is obviously completely subjective since males have no way to directly compare the experience. Non-ejeculatory orgasms become more likely for those with the predisposition to have them, if for no other reason than the fact that ejeculatory orgasms are difficult or impossible to achieve, and the need for sexual release forces a rewiring of perceptions and responses. It has been occasionally reported that sensitivity to air-born allergens decreases. Dramatically reduce facial hair growth in most people.