Orthopedic consultation is indicated for pathologic fractures. A variety of medications may be required to correct various endocrine and metabolic derangements. Some of these include medroxyprogesterone acetate, testolactone, bromocriptine, propylthiouracil, ergocalciferol, and calcitonin. Therapy should be conducted by a qualified endocrinologist. Typically does not stop acute bleeding episode but produces normal bleeding episode following withdrawal.
Some agents have dopaminergic properties, which inhibit prolactin secretion.
Antithyroid agent - Used in the palliative treatment of hyperthyroidism. Can expect a higher response when serum calcium levels are high. Onset of action is approximately 2 h following injection and activity lasts for 6-8 h. Contraindications Documented hypersensitivity Interactions None reported Pregnancy B - Usually safe but benefits must outweigh the risks. Ablation of hyperfunctional endocrine tissue should be arranged early.