The soil should dry completely between waterings. For this reason clay pots are better suited for growing Desert Rose than plastic pots. Water sparingly during winter months. Desert Rose can be grown from seed or cuttings. The best time for either method is in the spring.
Seeds germinate easily, and seedlings grow without any special attention.
Propagation by cutting is easy. Cut end shoots and let dry for a day or two. Be careful of the toxic sap. Stick shoots into a pot of moist soil, and provide bottom heat. Keep soil moist.