EDTA anticoagulant may interfere.
Serum lipase increases with hemodialysis.
Therefore, predialysis blood samples are recommended for lipase measurement. Coexistence of increased serum amylase with normal lipase may be a helpful clue to the presence of macroamylasemia. Lipase is elevated with amylase in acute pancreatitis, but the elevation of lipase is more prolonged. Electrolytes, serum calcium, glucose, and acetone are also often needed.