The college maintains a high standard of behavior for Canisius faculty. Finally, the Jesuit presence on campus is in itself a daily reminder of the values represented by the order and its founders. A Mass of the Holy Spirit initiates the academic year and offers students spiritual support and inspiration in their scholarly pursuits. The Campus Ministry Office sponsors religious services and activities in which students can worship, become involved in volunteer work, or learn more about social justice issues. Religious services, including a Sunday evening Mass, are scheduled regularly in the college's Christ the King Chapel.
Students have the opportunity to serve as lectors, sacristans, and Eucharistic ministers.
Each semester, students may take part in weekend retreats that offer spiritual renewal. Campus Ministry staff are available to counsel students individually and help them explore the religious and spiritual dimensions of their lives. Students regularly prepare and serve meals at local soup kitchens, help build and renovate homes through their chapter of Habitat for Humanity, and tutor children and refugees. They volunteer at a local runaway shelter, visit the elderly, and raise money for charitable groups. Incoming Canisius students attend mandatory orientation programming regarding the risks of drug use, followed by peer education programs throughout the academic year.