This stage has a high cure rate. Stage B1 Cancer has penetrated into but not through the muscularis propria. T2 Stage B2 Cancer has invaded the muscularis propria into the serosa or perirectal tissue. T3 Stage B3 Tumor has invaded nearby organs or tissues. No lymph node involvement N0 Stage C1 Stage B1 plus one to three regional lymph node involvement.
Studies are underway to determine if adding or using leucovorin is better.
Patients should also be considered for entry into clinical trials comparing postoperative chemotherapy, radiotherapy, or biological therapy, alone or in combination. No distant metastases. M0 Stage D Distant metastases is present. Survival rate after treatment is generally less than 5 years. For more information on the staging and classification of colon and rectal cancer from Johns Hopkins Oncology Center, click here .