The purpose of the tactile receptor studies is to develop an understanding of the stimulus encoder characteristics of tactile mechanoreceptors. Spectroscopic Measurement of Blood and Tissue Chemistry Applications of optical spectroscopy for the noninvasive measurement of blood and tissue chemistry, ultimately to be able to perform chemical analysis and diagnosis without removing a sample from the patient. Currently investigating the use of near infrared spectroscopy in combination with in-vivo chemometric techniques to determine tissue pH, blood hematocrit and electrolyte concentration. Also interested in the application of this technology in the triage and treatment of trauma patients and diagnosis of vulnerable plaque. The Center for Tissue Engineering at UMMS focuses on the generation of tissues for clinical applications.
Tissues studied include cartilage, bone, tendon, fascia, skin, spinal cord, liver, and pancreas.
Of specific interest is mechanical stimulation of cells and mechanisms of mechanotransduction. Particular attention is focused on determining structure-property relationships in engineered tissues. Ultrasound Measurements Applications under current investigation include detection of arteriosclerotic plaque and skin examination, for evaluating injuries, burns, and skin cancer. Doppler ultrasound is used for detection of motion, and the clinical applications include blood flow imaging and fetal heart rate monitoring. A Doppler project dealing with the detection of blood clots in the leg, a condition called deep vein thrombosis, is presently being carried out.