In OI, a person has either less collagen or a poorer quality of collagen. Collagen testing, which is done through a skin biopsy, is used to determine the amount of collagen present and its structure. Because of the complexity of the test, as well as the limited number of laboratories that are qualified to do the testing, it may take 3 to 6 months before test results are known. Inheritance factors OI can be dominantly or recessively inherited and can also occur as a mutation. Therefore, individuals with OI and parents of children with OI are strongly encouraged to seek genetic counseling to determine the likelihood of OI recurring in their families.
Treatment is directed toward preventing or correcting the symptoms.
Care of fractures, extensive surgical and dental procedures, and physical therapy are often recommended for persons with OI Wheelchairs, braces, and other custom-made equipment are often necessary. Individuals are encouraged to seek out medical centers where all aspects of OI, including biochemical, orthopaedic, dental, and hearing problems can be treated. This treatment involves inserting metal rods through the length, of the long bones to strengthen them and prevent deformities. Medication to treat OI is now being tested in many centers. Shriners Hospitals is doing this on an experimental basis.