Usually it is self-limiting, meaning that is resolves on its own or does not progress. Many cases require no treatment. Sometimes, however, it progresses to the point of fibrosis, the formation of scar-like fibrous tissue, which pernamently impairs the ability of the affected organ to function. Corticosteroids are the mainstay of therapy. They help suppress the inflammation and prevent granulomas and fibrosis from forming.
Sarcoidosis is characterized by the formation of what are known as granulomas.
A granuloma is a small, granular inflammatory lesion. Granulomas are characterized by a nodular appearance and a unique cellular pattern that can be seen through the microscope. They can form on nearly any part of the body, internal or external. There are many different types of granulomatous diseases, from Crohn's disease to tuberculosis. The cells that make up a granuloma are from the immune system.