There's the time spent on voice mail, e-mail, reading everything she needs to know about her company and job, trying to make sure she has adequate child care and picking up and dropping off her kids. There's the cost of living in the Bay Area and knowing that she has to keep going for the higher-level job but still wanting a life. It's an excruciatingly painful situation, where the person is in some state of burnout and knows it, but doesn't see any way out. And it's topped off by some doubts about whether she even likes what she's doing. I think I see more of them.
Work is a source of physical and emotional distress on the whole person.
The range is amazing. Carpal tunnel syndrome. People with sleep problems who can't get their internal clocks working appropriately. People with behavioral problems who can't get along with others. Who's going to wash the socks and clean the dishes, not to mention the child- rearing considerations.