The most common site for Wilm s tumor to metastasize is the lungs. In a pproximately 5 to 10 percent of children with Wilm s tumor, both kidneys are involved. It is uncommon for Wilm s tumor to run in families. Less than 2 percent of cases will have an affected relative. These mutations generally arise after birth, but, in some cases, children are born with a genetic alteration that predisposes them to cancer.
Tumor suppressor genes usually suppress the growth of tumors and control cell growth.
When altered, they no longer control cell growth, and tumors may form. Tumor suppressor genes usually suppress the growth of tumors and control cell growth. When altered, they no longer control cell growth, and tumors may form. Oncogenes control cell growth, but, if mutated, uncontrolled cell growth may result. The following are the most common symptoms of a Wilm s tumor.