Serotonin is thought to play an important part in shaping mood, thought processes, sleeping patterns, eating patterns, reaction to external stimuli and control of motor activity. Many medical experts believe that low levels are associated with depression. The chemical is produced by one neuron and released into the synapses, transmitting information to another neuron before being absorbed back into the first in a process known as reuptake. An MDMA pill takes effect after 30 to 45 minutes, starting with little rushes of exhilaration. These are sometimes accompanied by feelings of nausea and disorientation.
Some users also find their stomach starts churning.
Others experience a mild panic, especially if they're unfamiliar with the drug. Such negative effects don't usually persist for long, though. The peak effects of MDMA are felt 60 to 90 minutes after ingestion and last for two to four hours, followed by a gradual comedown. MDMA enhances physical sensations. The sense of touch is heightened, food may smell and taste different to normal, and many people say that music sounds better.