There are four major areas of research in Dr. Nephew s lab.
Tamoxifen is the most common treatment for breast cancer.
In addition, the drug will prevent breast cancer development in healthy, cancer free women. However, because tamoxifen acts like the hormone estrogen in some tissues, the drug has side effects, including increasing a women s risk for uterine endometrial cancer. One project involves understanding the uterine effects of tamoxifen at the molecular level. Epithelial ovarian cancer. In the U.S, some 25,400 women will develop ovarian cancer and 14,500 will die from it in 1999.