Aspirin blocks probenecid's effect. Continue colchicine for prophylaxis as above. 50 to 100 mg PO BID may be given. This is especially useful for those patients who must take aspirin. Drug that decreases production.
Side effects are rare but can be serious.
Calcium Pyrophosphate Deposition Disease Overview. A degenerative joint disease characterized by the accumulation of calcium pyrophosphate crystals in articular cartilage and periarticular tissues. May be idiopathic or associated with a variety of metabolic diseases. An acute inflammatory attack that involves one or more joints that can last for several days. Attacks can be very similar to gout, though usually not so severe.