Screening's age of insecurity May 2001, Vol. The data are fruitful and multiplying. Many crucial target systems have been well characterized, and druglike behavior is better understood. Yet the pace of research remains frenetic, and the competitive landscape cutthroat. That's because organizations have little to show for all of the innovations of the 1990s, at least in terms of new chemical entities.
Screeners seem confident in their programs' ability to generate data.
But they are less sure about whether they and their organizations are doing the best things with data generated. We have more than ever to choose from in terms of targets, compounds, and options for what we should be doing next. But we're discovering that all the data around us isn't making the answers come any easier. In the beginning, there was screening. Then came the 96-well plate and the concept of increasing throughput.