The symptoms include cognitive impairment, especially of memory and concentration, depression, general fatigue, sleep disorders, headache, arthralgia, sore throat, muscle fatigue on repetitive movement, and muscle pain or tenderness. The signs can also include low-grade fever, lymphadenopathy and localized muscle group weakness.
Some patients do poorly on certain psychometric tests.
Although morbidity may be high, sometimes for many months, and relapses occur, there are no documented fatalities. There is no clear-cut associated histopathology to help document the nature of the illness. Biological samples include any biological material, such as blood, tissue, or cells, which might be infected with the NMA virus or harbor antibodies, antigens, protein, or nucleic acid fragments specific to an NMA virus. The method also detects the presence or absence of antigens specific for an NMA virus. The method detects the presence or absence of nucleic acid sequences substantially similar to those encoded by an NMA virus.