That's why people still do research. They just don't explain a problem away with a supernatural answer. The difference here lies in the ability to not explain or evvision away this could evolve in a gradualistic fashion. If you examine the pathway closely, you will see that it could not have, unless by chance several enzymes all appeared spontaneously at the same time.
Similar problems abound in other physiological systems.
Many evolutionists have come to see this problem as real. In Darwin's time , all that was known were the anatomical observations of eyes or other organs. Now, we have come to understand the underlying mechanisms of these systems. And this is where Darwinism fails, at explaining the origins of molecular systems, the foundation on which all life rests. You are the one who says supernatural causes are invoked by me, which is not what my point is about.