You are to circle the letter of the correct answer directly on the test. Styrene is metabolize to the very toxic epoxide shown below by cytochrome P-450. The body detoxifies the epoxide by using glutathione, and the product is eliminated as a mercapturic acid. The deuterium labeled anisole shown below undergoes aromatic hydroxylation to yield a phenol. Which of the following represents a reasonable structure for the final product.
Warfarin is a widely used anticoagulant.
In determining the partition coefficient, you partition 100 mg between 5.0 ml of water and 5.0 ml ethyl acetate. Measurement of the organic phase shows that 80 mg is present. The answer cannot be calculated from the information given. Suppose you were to partition 10 mg warfarin between 1 ml of water and 1 ml of ethyl acetate. The answer cannot be calculated from the information given.