The National Multiple Sclerosis Society sponsors an MS genetic repository which should serve the identification and analysis of MS relevant genes. The MSDB is the central infrastructure facility that provides genomic DNA of Multiplex MS families and supports research assignments for qualified investigators. You may also contact us at our email address .
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MSDB Repository Multiplex MS families are located by reference to the MS registry at UCSF, by physician referrals, by collaborative arrangements with other MS centers in the United States, and by advertisements in MS newsletters and at MS functions. After initial contact with the propositus, a brief telephone interview is used to help determine eligibility for the study. A detailed family history is then obtained using a family history questionnaire. At the time of blood drawing, each family member is interviewed in detail, with a focus on family history of neurologic and other medical disorders. Diagnostic uncertainties are more important in MS than in most other neurological disorders.