Alpha GST in Human Hepatocytes Pi GST in Human Bilary Epithelium Traditional markers of liver injury respond relatively slowly to the onset and resolution of liver injury possibly leading to late initiation of therapy and its unnecessary prolongation. Therapy Monitoring Serum alpha GST levels decline rapidly following the initiation of successful anti-rejection therapy. A similar picture is seen with biliary pi GST levels. The close association between GST levels and hepatic status may enable therapy to be started and completed at more appropriate time points, reducing hepatic injury and iatrogenic injury.
Shorter hospital stay.
Less severe rejection episodes. Fewer biopsies performed. Trull A.K. et al. Platz, K.-P. et al. Determination of alpha and pi GST will improve monitoring after liver transplantation.