Then, the effect of chlorine substitution on cyclohexane was studied with chlorocyclohexane. These compounds were selected to be studied given their vapor pressures and their potential energy barriers. The philosophical component includes sections on what constitutes seeing with instruments, the relationship between theory and instrumentation, and assessing the progress of science by tracking the progress of instrumentation. In the section on seeing with instruments, the issue of seeing with the NMR is discussed against the backdrop of the debates on seeing with microscopes, and then a new definition of seeing is proposed. In the next section first the debates on the relationship between theory and instrumentation are outlined, and then a new relationship is proposed.
Solvent effects have a significant influence on the rate of rotation.
The solvent effects on the rotational barrier of DIPA were studied using dynamic Nuclear Magnetic Resonance Spectroscopy. Standard 1D and a 2D COSY spectra of DIPA were used to completely characterize its chemical shifts and coupling constants, and determine how protons were coupled to one another. The experimental data corresponding to the methyl region of the DIPA spectrum was imported from the JEOL NMR spectrometer, and loaded into a customized Microsoft Excel spreadsheet. This Excel spreadsheet calculates a simulated NMR lineshape assuming the DIPA methyl resonances to be an uncoupled A3B3 two-site exchange system. Using the Eyring equation, D G s for the barrier to the C-N internal rotation of DIPA were calculated.