Our results and the comparison with the oocyte data reveal that it is also the dimer which is the physiological opening-closing unit of the AChR in the oocyte membrane. The larger macrochannel events are multiples of the dimer or of the monomer conductances. Acetylcholine receptor reconstitution, calcium inhibition, channel cooperativity, oligochannel, single channel events. HOME Journals Catalogue Journal Cover Page Issue Contents Archives of Physiology and Biochemistry 1996, Vol. Thiamine deficiency leads to reversible and irreversible brain lesions due to impaired oxidative metabolism.
Thiamine is taken up by neuroblastoma cells through a high affinity transporter.
Most of the TDP however has a low turnover and is associated with PDH and KGDH in mitochondria. These channels are inhibited by oxythiamine from the outide. In addition to the role of TTP in the regulation of chloride channels, thiamine itself, or a presently unknown analog, may have trophic effects on neuronal cells. Chloride channels, neurotransmission, nerve conduction, thiamine, thiamine triphosphate. HOME Journals Catalogue Journal Cover Page Issue Contents Archives of Physiology and Biochemistry 1996, Vol.