Epigastric distress, anorexia , nausea , vomiting, diarrhea, constipation , abdominal cramps. Thickening of bronchial secretions, tightness of chest and wheezing , nasal stuffiness, respiratory difficulty. There is no information to indicate that abuse or dependency occurs with azatadine maleate. Pseudoephedrine, like other central nervous system stimulants, has been abused. At high doses, subjects commonly experience an elevation of mood, a sense of increased energy and alertness, and decreased appetite.
Some individuals become anxious, irritable , and loquacious.
In addition to the marked euphoria , the user experiences a sense of markedly enhanced physical strength and mental capacity. With continued use, tolerance develops, the user increases the dose, and toxic signs and symptoms appear. Depression may follow rapid withdrawal. Concomitant use of antihistamines with alcohol , tricyclic antidepressants, barbiturates, or other central nervous system depressants may have an additive effect. When sympathomimetic drugs are given to patients receiving monoamine oxidase inhibitors, hypertensive reactions, including hypertensive crises, may occur.