Each week, one of these Perspectives is selected for enhancement. Enhancements consist of hyperlinks to related web sites, either referring to specific statements within the Perspective or providing more general background information. Links to web pages of authors and their institutions are also included. The Perspective in the paper journal is a brief review, but the Enhanced Perspective on the web is a pathfinder leading the reader to web resources related to a very specific topic of current interest. Conclusions HighWire has succeeded in its mission to develop a significant web space for high-impact scientific journals published by or for professional organizations and scientific societies, and the list of journals in development suggests a high rate of growth in the future.
Significant challenges remain for web publishing.
Archival issues need to be resolved, particularly as electronic-only publication grows and the paper journal no longer serves as the archival format. Electronic-only publishing also suggests that the issue model of journal publishing may become obsolete. Electronic-only articles need to be presented in a form that can be cited and located. The diversity of pricing models for electronic publications will continue to confuse subscribers. It will be interesting to watch as HighWire moves forward on these and other issues facing electronic publishing.