Different database systems have different strengths and weaknesses. Most of these deal with the size of the company in question. Filemaker is an extremely flexible client-based database that excels in small business applications. It is quick to develop in, and has a more advanced user interface than is available through web browser-based systems. If your company works out of a single location and has fewer than 50 employees, a Filemaker solution is likely to be an excellent fit.
Users access a central server using their web browser.
Since everything is browser-based, clients can access pertinent information as well. The number of connected users is practically unlimited, and the system can be accessed from any standard speed internet connection. Excellent scalability, a solid choice for companies that desire a strong web presence, whose employees telecommute, or that share data between locations. Cheaper than WebObjects, but less robust.