Walleye are the primary sport fish in the reservoir. The walleye population in the reservoir is maintained through natural reproduction with high quality fishing available in the spring. Meredith Reservoir also has an excellent smallmouth bass population. Most of the reservoir is rocky habitat, which is preferred by smallmouth bass. A number of 4 pound and larger fish are caught from Meredith each year.
White bass provide an excellent fishery, especially during summer and fall.
Largemouth bass are limited in the reservoir due to limited habitat. Crappie fishing is generally good with occasional years of excellent fishing. The upper reservoir is very turbid with suspended red clay while the lower reservoir is clear. In most of the reservoir rock ledges, rock piles, and steep drop-offs provide cover for game fish. The peak period for walleye fishing is from April through June.