Signs and Symptoms MGUS is a chance finding in people with no symptoms. If a person has symptoms of myeloma or similar disease then the diagnosis of MGUS is ruled out. Diagnosis MGUS is often a chance finding when a person is having blood tests done either as part of a routine check-up or because of some unrelated medical problem. Often the initial finding is just of a high level of protein in the plasma. Further tests are done to find out which of the several forms of protein is increased and whether the increase is monoclonal.
Treatment See below.
As most people with MGUS will never develop any symptoms they do not require any treatment.