And just like other stimulants, the drug can also trigger impulsive, erratic behavior by increasing the action of two neurotransmitters, norepinephrine and dopamine. At higher dosages, or with chronic use, feelings of heightened confidence and arousal can quickly spin off into paranoia, irritability, and severe depression. First synthesized in 1928 and tested as both a diet drug and antidepressant, methcathinone's dangers were thought to outweigh its potential value and it was never distributed commercially in the United States. Physical side effects include loss of appetite, profuse sweating, dehydration, elevated heart rate and body temperature, and uncontrolled shaking. Psychological effects include anxiety and irritability.
Tolerance often develops rapidly as does dependence.
Early withdrawal symptoms of anxiety and profuse sweating can precede convulsions, hallucinations, and severe depression. I controlled substance by the Drug Enforcement Administration in 1993. Since then, hundreds of cat labs have been seized throughout the Midwest. All rights reserved. It Now Foundation.