Consideration is given to both analytical and process validation issues that are critical to successful manufacturing. The course covers fundamental principles of downstream processing with practical examples and case studies to illustrate the problems and solutions faced by the practitioner. It is intended to provide both insight into and an overview of downstream processing for individuals actively engaged in process research and development, as well as those who manage and innovate in the biochemical process industry. Increasingly, scientists and engineers engaged in fermentation and cell culture development attend the course to better understand the context of the whole process. The course faculty have worked together for over ten years teaching this course.
Time is provided for group interaction with the faculty and other attendees.
The course begins with an introduction to the recovery problems created by fermentation, cell culture, and enzyme technology. The program is under the direction of Professor Charles L. Cooney. About the Course Director Charles L. Cooney Charles L. Cooney is Professor of Chemical and Biochemical Engineering and Executive Officer in the Department of Chemical Engineering and Co-Director of the Program on the Pharmaceutical Industry at MIT, Cambridge, Massachusetts. He obtained his Bachelor's degree in Chemical Engineering from the University of Pennsylvania in 1966, his Master's degree and PhD degree in Biochemical Engineering from MIT in 1967 and 1970, respectively. After working briefly at the Squibb Institute for Medical Research, he joined the faculty of MIT as an Assistant Professor in 1970, and has been a full Professor since 1982.