The phagocytes may either be in the tissue site or be recruited into the tissue from a distance. Following the initial infection immunity develops but does not fully protect against further attacks. First ailment of HSV type infections presents itself mostly in infants and small children, which may be mild and unnoticed. However, when lesions acquire the severity is usually harder than in recurrences. After an incubation period of four to five days the symptoms begin with fever, malaise, restlessness and excessive dribbling.
Vesicles appear in white patches on the tongue, throat, and palate.
Infection involving the eye may manifest as a keratoconjuctivitis, or later, choriorenitis. Splashing saliva or fluid from a vesicular lesion directly into unprotected eyes can cause an infection as well. Symptoms include fever, pain, blurring of vision, swelling, watery eyes, sensitivity to light, and secondary bacterial infection. The most common location is around a fingernail, where the breaks in the skin often appear. Contamination results from through touch with a vesicular lesion on a patient s lip or with saliva that contains viruses.