The data from the study was presented at the 1996 Pediatric Academic Societies' Annual Meeting. The children using these techniques experienced fewer headaches. And, for the first time in a controlled study, we've shown that the same type of mast cell activation that occurs in adult migraine is also present in children. Mast cells are responsible for releasing neurotransmitters in the brain that cause changes in the vascular and autonomic systems, and result in migraine symptoms.
Scientists can determine mast cell activation by measuring an increased level of tryptase in urine.
For example, some foods believed to trigger migraine symptoms are also associated with activated mast cells. In this new study, the use of cyberphysiologic techniques practiced by children over a six month period resulted in a reduction of tryptase. The study involved 30 children, ages 5 to 12, who met the International Headache Society classification for juvenile migraines. During their first visit, the children were taught a progressive relaxation exercise, and how to focus on pleasant imagery. They were asked to practice these techniques twice a day for ten minutes.