The usual duration if treatment is seven to ten days. Topical administration must be accompanied by systemic administration. Sulfonamide solutions darken on prolonged standing and exposure to heat and light. Do not use if solution has darkened. Yellowishness does not affect activity.
Sodium sulfacetamide is a sulfonamide with antibacterial activity.
Sodium sulfacetamide is readily absorbed from the gastrointestinal tract when taken orally and excreted in the urine, largely unchanged. The biological half-life has been reported to be between 7 to 13 hours. Hypersensitivity reactions may occur when a sulfonamide is readministered, irrespective of the route of administration. Sensitivity reactions have been reported in individuals with no prior history of sulfonamide hypersensitivity. The overall prevalence of sulfite sensitivity in the general population is unknown and probably low.