Because CMV-specific IgM may be produced in low levels in reactivated CMV infection, its presence is not always indicative of primary infection. Only virus recovered from a target organ, such as the lung, provides unequivocal evidence that the current illness is caused by acquired CMV infection . If serologic tests detect a positive or high titer of IgG, this result should not automatically be interpreted to mean that active CMV infection is present. Currently, no treatment exists for CMV infection in the healthy individual. Antiviral drug therapy is now being evaluated in infants.
Vaccines are still in the research and development stage.