These Physl 341 notes are modified from Bio 303 lecture notes , originally prepared by Dr. Paul Patton. Even though no visible IPSP is produced, the net effect is still inhibitory if the reversal potential is less than spike threshold. Inhibition without a visible IPSP is called silent inhibition or shunting inhibition . Usually mediated by Cl - channels. Presynaptic inhibition Inhibitory synapse onto presynaptic terminal of excitatory synapse Post-synaptic inhibition momentarily reduces ability of cell to respond to excitatory input, Presynaptic inhibition specific to particular input, without affecting response to others.
Vesicles are site of neurotransmitter storage and release into synaptic cleft.