Differentiation of the epithelium has profound effects on the arachideonicacid metabolism. Experience with molecular biology techniques required and an interest in pulmonary biology desirable. Candidates should have experience in molecular biology, cell biology, or biochemistry. The role of nuclear receptors and other mechanisms of action of retinoids. The role of nuclear receptors and other transcriptional factors in the control of gene transcription is being investigated.
Studies involve characterization of promoters of several genes.
Applicants must have experience in molecular biology techniques. Studies are aimed at understanding the mechanisms by which organisms produce mutations. This is a tenure track position to develop an independent research program in cellular and molecular mechanisms of respiratory biology and diseases. Extensive postdoctoral experience in molecular biology, developmental biology, signal transduction, or biochemical mechanisms of inflammation is required. Regulation of gene expression is studied using Northern analysis, RT-PCR, protein immunoblotting, immunohistochemistry, and in situ hybridization.