Sialoacryodenitis in Rats Rats are the natural host for this highly contagious viral disease. The disease is usually self-limiting in young rats. Recently weaned mice may also be affected. The disease is spread from affected individuals through respiratory aerosol or direct contact with respiratory secretions. Infected rodents carry and secrete the virus for about seven days.
Signs are variable depending on the age and immune status of the affected rat or mouse.
The most serious signs are seen in 2 to 4 week old rats with no maternal antibody protection. Initial symptoms include squinting, blinking, and rubbing of the eyes. Sneezing and swelling in the neck area develop later. Respiratory signs may be present, especially if complicated by Sendai virus or murine mycoplasmosis. Clinical signs are nonspecific, but primarily appear as ruffled fur, lethargy, hunched posture and poor appetite.