The temptation for the preacher is either to ignore it or to be preoccupied with it. I refuse to limit a discussion about sex to the lectionary of secular society. Loneliness is a huge one. Most people I've talked to who have engaged in sex outside of marriage are not promiscuous, but they are lonely. The mistake they make is thinking that sex will take care of the loneliness.
Sex just complicates their lives.
Sexual activity, for example, is fundamentally a question of choices. I've also spoken on sex as a subtheme of stewardship. The least helpful way to speak about sex is as an issue. As soon as you do that, you're in an argument with your congregation. I want to talk about it pastorally through some of these human themes, giving people relief from their struggles.