Serum phosphorus is decreased. Serum alkaline phosphatase may be increased. Bone X-ray shows bone reabsorption or fractures . Imaging of the kidneys or ureters shows calcification or obstruction. ECG may show abnormalities.
Treatment depends upon the severity and cause of the condition.
Mild hypercalcemia may be followed medically unless impaired renal function, bone demineralization, or high blood pressure is present. For symptomatic , severe hypercalcemia, hospitalization may be required. Rehydration using intravenous fluids may be started. The outcome is best for a mild case. The disease is usually progressive unless the parathyroid glands are removed.