Only 2 patients completed 24 weeks of therapy. There were no significant beneficial effects on any of the measured outcome measurements of infection severity. Many patients complain that their eye drop bottles don't last as long as they should. The problem is that eye drops are hard to use. Patients often squeeze out too much, or miss the eye and have to redose.
Some patients think more is better.
Patients especially complain about Timoptic XE and Xalatan . Here are some hints to help. Timoptlc-XE 5 ml should last about 60 days when patients use just one drop in each eye once a day. The bottle has to be shaken once before using to make the drops more fluid and easier to dispense. Patients should also be told to stop squeezing the bottle as soon as the drop falls and to continue to hold it upside down for a second or two.