It reduces cholesterol and cholinesterase levels. In simplest terms, the net effect of artichoke extract appears to be the result of both an activation of and an interference with cholesterol metabolism. That is, it mobilizes fat stores from the liver and other tissues such as white adipose tissue, and these fats pour into the blood from which they are subsequently excreted from the body. Cynarin decreases the rate of cholesterol synthesis in the liver, enchances biliary excretion of cholesterol, and increases conversion towards the bile acids. Not only cholesterol but other blood fats such as triglycerides can be reduced through the use of artichoke.
Scientific evidence supports the use of artichoke as a liver remedy.
Cynarin is the active ingredient contained in the plant, and its highest concentration is in the leaves. The dose tested was 250 mg and 750 mg daily. The mean serum cholesterol and triglyceride concentrations were not significantly changed within 3 months. Cynarin, administered per os, has no hypolipidaemic effect in familial Type II hyperlipoproteinaemia. Traditional medicine in health care.