The topics within Bioscience Engineering are purification of biomolecules , processing of new biological entities and environmental engineering . This enables purifications to be performed without prior removal of cells or broken cell debris. Following pioneering work within the Department, this process is now used commercially.
Work continues in understanding the process in detail and improving performance.
Professor Howard Chase Adsorbents and contactors. Work has been carried out on modifying solid surfaces and the use of liquid perfluorocarbons to enhance separations by chromatographic methods. Professor Howard Chase Continuous Chromatographic Separations. In conjunction with an Austrian company, Dr Anton Middelberg is investigating the use of continuous chromatography to purify and process fusion proteins and peptides, and to improve the refolding of proteins. Cell disruption and permeabilisation.