Introduction - Venlafaxine is an antidepressant that selectively inhibits serotonin reuptake and is an norepinephrine inhibitor.
Withdrawal syndromes can occur after abrupt drug discontinuation of long term regimens.
Exegesis - We report six cases of withdrawal symptoms after venlafaxine discontinuation. Conclusion - Physicians must be aware of the frequency, rapidity and potent severity of these withdrawal syndromes. The usual dosage is 75 mgs per day. This dosage can be increased to 150 mgs per day and in severe depression to 225 mgs per day. Withdrawal syndromes have been observed after abrupt discontinuation of venlafaxine.