It occurs most often between the ages of 30 to 50. It is rare in children, but has been seen in infants as young as 3 months old. Night sweats may accompany the fever. Anorexia and weight loss are common. Involvement of the sinuses and nose may produce a bloody discharge, pain, and ulcers and sores around the opening of the nose.
Skin lesions are common, but there is no one characteristic lesion associated with the disease.
Kidney disease may have no symptoms but is readily diagnosed with laboratory studies. Eye problems develop in a significant number of patients and may range from a mild conjunctivitis to severe inflammation of the eyeball and the tissues around the eyeball. With treatment, most people recover within a year, although chronic renal failure may develop. Without treatment, the disease is fatal within a few months of diagnosis. Call your health care provider if chest pain , coughing up blood , blood in the urine , or other symptoms of this disorder are present.