This week's artwork was donated by Lonny, a pediatric cancer patient who received treatment at The Children's Hospital of Philadelphia . Numb chin syndrome as the initial manifestation of HIV infection. There will thus likely be a continued rise in the incidence and prevalence of ARM in the long term, even if effective antiretroviral and other AIDS-related therapies reduce their appearance in the short term. There are presently no curative regimens for the common ARM, with the possible exception of some lymphomas.
Survival is shortened by most, and treatment is often toxic and poorly tolerated.
Although some gene therapy strategies may work well in the HIV setting, the chronic viral infection, immunodeficient status of the host, the tendency for HIV-infected individuals to have altered drug metabolism and an increased rate of adverse drug reactions will likely present special challenges. Centro di Riferimento Oncologico, Aviano, Italy. No statistical differences were found in the general characteristics of the two groups at the time that BL was diagnosed. The data from this study show that patients with BL with and without HIV infection share similar clinicopathologic characteri- stics at presentation. Although the median overall survival is significantly shorter for patients with HIV infection, the DFS is identical for both groups.