Tobacco smoke contains toxic chemicals including carbon monoxide, cyanide, and polonium.
These chemicals have many adverse effects , including on reproduction, menopause, and in terms of causing impotence. Here is a summary of pertinent information, and some medical book and journal references for further reading. Note that the medically-alert King of Turkey, Sultan Murad IV, thereupon banned tobacco. Roth and Mitchell in the laboratories of the Battle Creek Sanitarium has shown that tobacco smoke destroys the power of reproduction in rats, affecting both males and females. The female has been found to be more easily affected than males.