The process by which organic tissue becomes hardened by a deposit of calcium salts within its substance. The escape of blood from the vessels. A local defect or excavation, of the surface of an organ or tissue, which is produced by the sloughing of inflammatory necrotic tissue. The formation, development or presence of a thrombus. An aggregation of blood factors, primarily platelets and fibrin with entrapment of cellular elements, frequently causing vascular obstruction at the point of its formation.
Some authorities thus differentiate thrombus formation from simple coagulation or clot formation.