The nonceliac food-induced enteropathy has been less frequent and less severe in the last 25 years. Cases more recently described tend to present with patchy intestinal lesions. Usually, the syndrome affects infants in the first months of life. For gluten-sensitive enteropathy, refer to celiac disease . Protein-losing enteropathy is a common finding in children with cow s milk protein intolerance.
Some infants can present with pronounced protein-losing symptoms after introduction of cow's milk.
Food-induced proctocolitis usually occurs in the first few months of life. Symptoms include diarrhea and blood in the stools. Affected infants generally appear healthy and have normal weight gain. The onset of bleeding is gradual and initially erratic over several days, then progresses to streaks of blood in most stools that can elicit suspicion of an internal anal tear. Bowel lesions generally are confined to the distal large bowel.