If public transportation is both safe and reliable, you could opt to move into a home a bit further away from your job than you would have chosen had public transportation not been available. Proximity to medical care is particularly important for the increasing percentage of our baby-boomer population caring for their aging parents and relatives. So before you slide on those rose-colored glasses and close the deal, check out that neighborhood. Come back during the evening hours. Find out who frequents the neighborhood and when.
Some neighborhoods have multiple personalities and attract a different crowd at night.
Talk to your Realtor, then talk to prospective neighbors. Drive around, and do your own research. Then, and only then, can you make an informed decision about the best neighborhood for you. They would appreciate the opportunity to be of service to you.