In the 1970's, the medical community had largely concluded that all estrogens were alike, i.e., they could be used interchangeably and all would affect the various tissues of the body in similar manners.
Studies suggest that effects vary significantly across estrogen therapy types.
Additionally, even when a single estrogen is used in an individual patient, the effects of will vary from tissue to tissue. Thus, future research will likely focus on the development of estrogens that target certain types of receptors. This targeting will allow specific organs and tissue types to be the focus of an estrogen medication. Restoring neurologic functioning through hormone replacement therapy Estrogen appears to have many positive effects on the brain, including maintenance of neurological functioning. Thus as the population ages, the rates of AD and other neurological diseases are expected to increase dramatically if current trends continue, particularly among the female population.