Typically, older windows in homes may be the areas most likely to have lead- based paint. This should be thoroughly checked if it is of concern to you. Watch out for extraordinarily cheap thermo-pane windows in newer construction, These have been known to last only four or five years, and again are quite expensive to replace. In the New England area, there are often highly humid conditions and a large range for air and ground temperature. This can possible translate into a very high degree of condensation on concrete, and might cause interior moisture, ruin floors, or invite insects.
Slabs are also less desireable for resale.
Expect basements to be somewhat moist in New England due to the same humidity already mentioned and due to natural condensation. Dehumidifiers are sometimes necessary, and should be installed in a way that provides minimal maintenance. There may be a problem hiding. Of course, New England is prone to termite infestation. Homes should be checked periodicaly, in the spring and summer especially, for termites and other wood-boring insects to protect your investment.