The excretion of protein in the urine is not as severe as with nephrotic syndrome . Urine specific gravity and osmolality show there is a failure to concentrate urine even when water intake is restricted. Arterial blood gases and blood chemistry may show metabolic acidosis . BUN and creatinine levels are used to assess level of kidney functioning. A kidney biopsy confirms the diagnosis of interstitial nephritis and is used to evaluate the extent of damage to the kidney.
Treatment focuses on treating underlying causes and relieving symptoms.
Avoiding the suspect medications may cause the symptoms to go away quickly. If dialysis is necessary, it usually is required for only a short time. Corticosteroids or anti-inflammatory medications may be of benefit in some cases. On rare occasions it may cause permanent damage including chronic renal failure . Call your health care provider if symptoms indicate interstitial nephritis may be present.