Simple antibiotics are effective therapy. It can occur in all parts of the world but is most associated with Asia although recent epidemics have been in South America. Cholera produces torrential diarrhea and vomiting. The disease spreads from feces to water. The patient dies from fluid loss unless Intravenous fluid replacement is given.
Vaccination can prevent it.
Maude Abbott Abnormalities of development of the heart occur during gestation due to misalignment of the vessels, cavities and septa that form in the embryo. Congenital abnormalities were first noticed in the 18th century with dissections by Farre in 1814. In these children the unsaturated venous blood is cycled into the systemic circulation. She was encouraged in her career by William Osler. Her career illustrates the handicaps that women of her generation suffered with due honour being given to them only posthumously.