Radiation treatment for metastasis is usually directed to just one area. Any side effects will be related to the area being treated. In general, nausea, fatigue, and skin irritation can result. More serious effects, like bone marrow suppression or secondary cancers, are possible. Chemotherapy and immunotherapy have many side effects, depending on the drugs used.
Side effects can be mild, such as nausea, temporary hair loss, and fatigue.
More severe nausea and fatigue can be treated with new medications. Side effects can also be life-threatening, with severe infections, secondary tumors, severe blood clots, or organ toxicity. Some treatments have late complications and people need continued medical care. The person is watched for any recurrence of metastases. Physical exams, blood tests, and tests for tumor markers are done.