The doctrines of systematic materialism and reductionism depend on the fact that some scientists deliberately avert their eyes from this question. There are two dimensions of reality which intersect in ourselves. Scientific materialism taken as a dogma means that all thought and inner human experience can be reduced to a set of scientific concepts, chemical reactions, electrical circuits, or quantum states depending on what ever is the current scientific fashion. Not only does such reductionism deny the dignity and richness of our own inner experience of ourselves. Also in the strictest sense it is unscientific.
Science seeks the fullest understanding it can reach.
On a purely descriptive material level a CD of Beethoven's 9th symphony is just some scratches on a metal disc. Deciphered it is a series of 1's and 0's in a complex pattern. Properly understood and appreciated it is a superbly moving piece of music. Deciphering, understanding and appreciating are activities that can only be themselves understood in terms of our own inner experience of our own consciousness. Reductionism is therefore sawing off the branch on which it is sitting.