The liver surface of this case shows granular change, suggesting the presence of a fine nodular formation in liver histology. Wilson's disease The liver in the non-cirrhotic stage of Wilson's disease is usually enlarged, and shows the characteristic spotty pigmentation. These spots are believed to be caused by cupper deposition in liver parenchyma. The magnified laparoscopic picture of liver surface observed in the case presented above. A terminal portal branch is seen in the middle of the picture.
Spotty pigmentation is obvious at the left upper corner.
Coarsely nudular liver surface with blue-gray color spots is characteristic in the cirrhotic stage of Wilson's disease.