Prior Dacarbazine is permitted. This outpatient treatment will be administered orally, twice a day for 5 days per week during a twenty-eight day cycle. Soft tissue sarcoma distantly metastatic, unresectable locally advanced or recurrent disease. Received one but not more than two prior chemotherapy regimens. Outpatient intravenous chemotherapy.
Trial is under development at the present time.
Patients will be evaluated by both the medical oncologist and transplant team. In most cases patients will be treated with three courses of chemotherapy prior to transplantation. Soft tissue sarcoma unresectable primary or metastatic disease. Patients must have received no prior gemcitabine. Prior adjuvant chemotherapy so long as relapse has not occurred within 6 months of the last dose of adjuvant chemotherapy.