Delayed apoptosis increased in a UVA dose-dependent manner. Zinc is an important metal for DNA protection and has been shown to have inhibitory effects on apoptosis. In addition, zinc chloride significantly decreased UVA1-induced early and delayed apoptosis. This data shows for the first time in normal cultured skin cells that UVA1 radiation induces apoptosis. This apoptosis appears higher 18 hours after the stress.
Zinc supplementation can prevent both immediate DNA strand breakage and early and delayed apoptosis.
Thus, this suggests that zinc could be of interest for skin cell protection against UVA1 irradiation. However, no study has specifically evaluated its relation to breast cancer risk of post-menopausal women. Thus, strenuous exercise appears to reduce breast cancer risk among post-menopausal women who do not gain sizable amounts of weight during adulthood. Similarly, the Listeria infection alone produced a significant increase on NK cells activity, which was observed at 48 and 72 hours after the inoculation of Listeria. However, when CV was administered in infected animals, there was an additional increase in NK cells activity which was significantly higher than that found in the infected groups.