Randomized Controlled Trial.
Vasomotor symptoms are very common among perimenopausal women, but also among orchidectomized men.
The cause of the symptoms is not the low steroid concentrations per se, but probably changes in central neuropeptide activity. Treatment was given for a total of eight weeks, twice a week during the first two weeks, and then once a week for the remaining six weeks. As recorded in logbooks kept by the participants, the frequency of flashes decreased significantly by more than 50 per cent in both groups, and remained decreased in the EA group, whereas in the SNP group it increased slightly again over the three months after treatment.