However, unlike what happens in primary adrenal insufficiency, the adrenal glands will continue to produce aldosterone. The symptoms of Addison's disease usually come on gradually. There is fatigue, muscle weakness, loss of appetite, and weight loss. As the condition worsens, patients often experience nausea, vomiting and diarrhea. As blood pressure falls, patients will feel lightheaded or dizzy, especially while standing.
Skin changes are also common.
There is increased pigmentation or dark tanning of the skin on both exposed and unexposed parts of the body. This is most noticeable on scars, skin folds, and pressure points as well as on the lips and mucous membranes. Addison's disease may also cause irritability and depression. Because of salt loss, patients often crave salty foods. Because Addison's disease tends to come on slowly, it is frequently ignored until a stressful event such as an illness or accident causes a sudden and dramatic worsening of symptoms.