For instance, if friends get silly and laugh after smoking marijuana, chances are you will respond the same way. There is an expectation of the effect. The mood you are in before taking the drug will also impact how you are effected. If your body is accustomed to ingesting a drug, you may need more to get the same effect. This is called tolerance and your body has adjusted to need more of the same drug to reach the previous effect.
Some drug interactions are deadly.
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