Yet, there are significant differences. CS molecules are at least fifty to three hundred times larger than glucosamine sulfate molecules. Due to this, most researchers argue that CS molecules are too large to be absorbed effectively by the body. In fact, the absorption rate of GS is estimated to be ninety to ninety-eight percent, while CS is approximately zero to thirteen percent. Certain researchers further explain that any benefit received is due to the body s ability to breakdown CS to smaller molecules, such as GS, which is one of its building blocks.
Studies offer conflicting results.
Improvement was seen after 3 months of treatment and became more marked after 12 months. This supports the theory that CS molecules are too large to be effectively absorbed. Researchers continue to investigate and debate the effectiveness of chondroitin sulfate. At this time, glucosamine sulfate is the preferred nutrient as a primary treatment against osteoarthritis. It is possible that chondroitin sulfate may augment glucosamine sulfate s potency.