The voices Macbeth hears, cause him to be hyperalert and very anxious. He becomes very angry because his face must wear a mask to cover his false heart. Macbeth cannot be his real self but must be a hypocrite. Lady Macbeth cannot get her rest because of the fancies of her mind. The doctor responds that she is not sick.
Someone give that doctor a standing ovation.
Lady Macbeth finally dies, perhaps from suicide, while in her dark depression. Her remorse did nothing to save her and perhaps repentance seemed too high a price to her human pride. Macbeth, having lost his queen for whom he has murdered, decides life is meaningless. Yet Macbeth fights on, killing many in battle. He boasts he can best anyone born of a woman.