The committee's opinion about BRCA mutation screening is that population-based or even large scale implementation are not justified. The committee feels that specific management is indispensable and advocates the use of defined and evaluated procedures, and involvement in clinical trials. French physicians' attitudes towards mammographic screening and prophylactic surgery were not in complete agreement with the subsequently published French guidelines, the impact of which has now to be considered. Constantly evolving knowledge about the efficacy of preventive intervention will give practitioners new elements to integrate into their counselling. Progress report on ovarian cancer.
Tamoxifen is the most commonly prescribed adjuvant therapy for women with breast cancer.
It has agonist activity on the endometrium and is associated with an increased risk of endometrial cancer. Women with thickened endometrium underwent outpatient hysteroscopy. The remaining women all had benign features to explain the USS findings. TV USS is a poor screening tool because of the high false-positive rate. The low frequency of significant findings suggests that endometrial screening in asymptomatic women is not worthwhile.