Antacids decrease blood levels and decrease the effect of sulindac. It may increase the risk of light sensitivity and reactions with other photosensitizing medications. May increase the risk of hypoglycemia with insulin or oral hypoglycemic medications. The maximum dosage is 400 mg per day. Tinnitus, blurred vision.
Underlines indicates most frequent.
Monitor patient for rhinitis, asthma and articaria. Assess patient for pain and ROM before and 1-2 weeks after therapy. CBC and liver function tests should be periodically evaluated when receiving chronic therapy. Bleeding time may be prolonged for 1 day after discontinuation of therapy. Administering sulindac in higher doses than recommended does not provide increased effectiveness but may cause increased side effects.