An unpublished study conducted by Oregon Health Sciences University showed no toxic effects. The study measured long term toxicity of MSM over a six month period. Oregon Health Sciences University has treated more than 12,000 patients with MSM at levels above 2 grams per day with no serious toxicity. The body will use what it needs and after 12 hours, will flush any excess amounts out of the body. MSM will flush what the body does not retain semi-permanently every 12 hours and because it is a free radical and foreign protein scavenger, MSM cleans the blood stream, so allergies to food and pollens go away in about 3 or 4 days.
Sulfur is critical for the synthesis of connective tissue, enzymes and immunoglobulin.
Dr. Michael Murray reported that sulfur is an essential nutrient for joint tissue where it functions in the stabilization of the connective tissue matrix of cartilage, tendons, and ligaments . He also commented that even healthy humans typically have a very low serum sulfate of 0.3 to 0.4 mm and synovial sulfur levels and even lower in persons with osteoarthritis. As far back as the 1930's, researchers demonstrated that individuals with arthritis are commonly deficient in the essential nutrient sulfur. Restoring sulfur levels brought about significant benefit to these patients. Accelerated wound healing.