We seek to understand how immunologic tolerance to self molecules is established and maintained, and when tolerance is interrupted, pathogenesis of the autoimmune diseases that ensue. A new perspective of autoantibody action. Garza, K.M., Agersborg, S.S., Baker, E., Tung, K.S.K. Persistence of physiological self antigen is requied for regulation of pathogenic autoimunity.
T cells is compatible with normal ovarian function in mice.
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