Proximity and alignment in 2D are used in computer interfaces to show which options belong together.
Thrones are higher than commoners' seats to show social power.
People in social situations use proximity to show how intimate they want to be with others in the space. Orientation is also used, facing someone or turning away from them. Large architectural spaces are generally felt to invoke awe, while small ones may be oppressive or cosy, depending on a number of factors. As with many applications of computing, there is benefit in intelligently applying critical ideas from other media and other technologies, rather than looking only in our own backyard. Readers might be impatient at being asked what space is.