Test bleeds should be done approximately 10-24 days after the boost. These are guidelines only. Absolute time frames should be dictated by the investigator's experience or pilot studies. Injection sites should be monitored 2-3 times per week. Significant granulomas or abscesses should be brought to the attention of the LAR veterinarian for treatment.
Several methods are available for blood collection.
For assistance and training, consult the LAR veterinarian. Should antibody titers not be high enough, multiple boosters may be administered. For training or assistance, consult the LAR veterinarian. Additional Guidelines for Polyclonal Antibody Production in the Rabbit 1. The animal must be appropriately restrained or sedated for injections or bleeding.