They are useful in high doses early in the reaction, but morbidity and mortality actually may increase in association with corticosteroid use. Saline compresses may be applied to the eyelids, lips, and nose. Careful daily inspection is necessary to monitor for secondary superinfections. Prophylactic systemic antibiotics are not useful, especially in the current era of multiple-drug resistance. Antimicrobials are indicated in cases of urinary tract or cutaneous infections, either of which may lead to bacteremia.
Some authors recommend daily follow-up.
Some patients may require the services of a burn unit. Transfer criteria would be the same as for patients with thermal burns. Recurrences are possible. The majority of patients recover without sequelae. Development of serious sequelae, such as respiratory failure, renal failure, and blindness, determines prognosis in those affected.