My research interests are focused on clinicopathologic studies in gynecologic pathology. Recent and ongoing studies are aimed at investigating primary and metastatic mucinous neoplasms involving the ovaries utilizing both traditional clinicopathologic methods and immunohistochemical and molecular techniques. Other areas of interest include gynecologic cytopathology and diagnostic immunohistochemistry. A clinicopathologic analysis of 109 cases with emphasis on distinguishing pathologic features, site of origin, prognosis, and relationship to pseudomyxoma peritonei. Molecular genetic evidence supporting the appendiceal origin of pseudomyxoma peritonei in women.
Translational research has unlimited potential in cytopathology.
My goal in general is to be active in this exciting frontier, extending the diagnostic capabilities from the established morphologic criteria to include more specific and sophisticated tools such as molecular assays and other ancillary studies. One ancillary technique that exemplifies the combined modality approach is the addition of flow cytometry to the cytomorphologic evaluation of lymph node fine needle aspirations. I recently received a small grant for the use of culdocentesis to obtain cytologic material in women with adnexal masses, potentially facilitating early diagnosis and management of ovarian tumors. The Accuracy of Combined Cytopathologic and Flow Cytometric Analysis in Lymph Node Diagnoses. AutoCyte Processing of Non-Gynecologic Material.