Narcotic analgesic which produces its effect by stimulating opioid receptors in the brain. It is erratically absorbed after intramuscular injection . Peak effect after oral administration occurs in 1-2 hours. 50 mg to 150 mg intramuscularly, subcutaneously, or orally every 3 or 4 hours as necessary. Temporary hallucinations and hypotension.
Seizures can occur after high doses due to the metabolite normeperidine.
Combination with other CNS depressants may produce excessive respiratory depression. Hypersensitivity to meperidine. Journal of Head Trauma Rehabilitation .