Frequency of application should correspond with severity of infection. Treatment of uveitis requires use of topical, periocular, or systemic corticosteroids. The mainstay of this treatment for anterior uveitis is topical prednisolone acetate. This often is combined with mydriatic-cycloplegic and analgesic agents. Other ocular conditions, such as serous retinal detachment, optic neuritis, and cranial neuropathies, are presumed to be due to immune factors.
Treatment is directed toward the underlying infection and resultant inflammation.
Improvement of environmental sanitation, including water supplies and sewage disposal, will sharply reduce the incidence of typhoid fever. Travelers to developing countries should avoid consuming untreated water, drinks served with ice, peeled fruits, and other food not served hot. However, vaccinated persons should exercise dietary precautions. Bleeding usually is noted after the second week of illness, but perforation may occur unexpectedly after the patient has started to improve. Other complications include pneumonia, myocarditis, acute cholecystitis, and acute meningitis.