Visual field defects may manifest as the schisis cavity extends posteriorly. The schisis cavity may remain stable or slowly progress over several years. The occurrence of SR is approximately equal in males and females. The inner layer may be transparent and difficult to visualize. In advanced cases, the leading edge of the splitting retinal layers usually elevate acutely, resulting in a bullous cystic cavity.
Scleral depression fails to collapse the inner retinal layer.
The retinoschisis rarely extends into the macular region. SR is not associated with operculated or horseshoe-shaped retinal tears. Retinal detachments secondary to inner retinal layer holes alone or combined with outer layer holes tend to be elevated and large to total detachments. SR is commonly bilateral but not necessarily symmetrical. Flat type also is termed typical degenerative retinoschisis.