We use only quality organic components, biochemicals, ultrafiltered endotoxin-free water and high grade salts. The complex nature of serum makes it impossible to predictably avoid cellular adhesion artifacts , yet many investigators still report their findings with such media.
Whole serum serves as a source of adhesins, enzymes and surface modifying molecules.
TCx serum replacers were formulated to support a very broad range of cell types without added adhesins and other interfents. The quality of basal media can vary greatly from manufacturer to manufacturer. Most manufactures use inferior water and raw materials which contaminate a medium with mitogens like endotoxin. Celox set the industry standard for ultra-low endotoxin tolerance levels. Its defined formulation makes it ideal for critical studies of cytokines and other regulatory factors under controlled conditions.