Test code links throughout this Guide refer to the corresponding test in the User's Guide.
Viral isolation is the preferred method of laboratory diagnosis.
In cases of central nervous system disease, amplification techniques are the most sensitive. In the absence of this capability, serology can be used to support a clinical diagnosis of polio. A fourfold or greater rise in titers in sera bracketing the illness is much more convincing proof of disease association. No antibody detected. In Manual of clinical laboratory immunology , 4th ed.