The rash appears as poorly defined spots of various sizes, often bright red. Fever continues to rise and fall, sometimes for as long as three weeks. Bloodshot eyes may develop, and the eyes can become sensitive to light. The palms of the hands and soles of the feet often become red, and hands and feet may swell. Occasionally, a stiff neck will develop.
Some children have abdominal pain and diarrhea.
When the fever subsides, the rash and swollen lymph glands usually disappear. The skin around the toenails and fingernails often peels painlessly, usually during the second or third week of illness. The skin on the hands or feet may peel in large pieces. The knees, hips and ankles may become swollen and painful. Occasionally joint pain and swelling persist after other symptoms have disappeared, but permanent joint damage doesn't occur.