The duration of the breast mass ranges from 1 month to 26 years with tumor diameter ranging from 0.5 cm to 14.0 cm. Hence, histologic criteria are critical in differentiating benign from malignant lesions of smooth-muscle origin. Surgical treatment of leiomyoma is local excision. This is in contrast to the management of leiomyosarcoma, which dictates that mastectomy or wide excision with radiation therapy is the preferred management. Several histopathologic characteristics allow differentiation of this lesion from the more aggressive leiomyosarcoma.
Surgical treatment is local excision.
Prognosis is excellent based on the benign nature of these lesions. Leiomyoma of the breast. Am J Obstet. Diseases of the breast. Diaz-Arias AA, Hurt MA, Loy TS, et al.