As synchronous triple malignancies are extremely rare, two gynecologic cancers seem to ascribe to the suppressing state of the immunosurveillance mechanism by viral infection. Among diffuse tumefactions, the author diseases prolapse, inguinal hernias, hematomas, oedemas, vulvar varices, abcesses of the vulva and rare cases of elephantiasis. Each case is described and management is discussed. Excision of these tumours is always recommended as is pathologic surveillance. The histological picture of severe stage dysplasia or undifferentiat- ed vulvar intraepithelial neoplasia III is similar in three clinical entities, which should be distinguished because they differ with regard to clinical characteristics, development, prognosis and treatment.
Surgical excision is required.
Bowen's papulosis in the young female, known only since the last 2 decades, is the most frequent. It is clinically highly polymorphic. Fortunately, it is rare because its risk of malignant transformation is high. Its treatment has not been fully defined but should be as conservative as possible. This clinical distinction is not accepted in the English literature but to us seems of major importance given the need to apply appropriate treatment in each case.