Iron deficiency cannot be overcome by increasing dietary intake alone. Iron supplements are always required. Oral iron supplements are in the form of ferrous sulfate. The best absorption of iron is on an empty stomach, but many people are unable to tolerate this and may need to take it with food. Milk and antacids may interfere with absorption of iron and should not be taken at the same time as iron supplements.
Vitamin C can increase absorption and is essential in the production of hemoglobin .
Supplemental iron is needed during pregnancy and lactation because normal dietary intake cannot supply the required amount. The hematocrit should return to normal after 2 months of iron therapy, but the iron should be continued for another 6 to 12 months to replenish the body's iron stores, contained mostly in the bone marrow. Intravenous or intramuscular iron is available for patients when iron taken orally is not tolerated. Prognosis With treatment, the outcome is likely to be good. In most cases the blood counts will return to normal in 2 months.