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Trazodone is a weak serotonin reuptake inhibitor drug with other effects on brain neurotransmitters.
It is used to treat people with depression . It is also used to treat people during cocaine withdrawal. Trazodone was associated with increased serum digoxin levels in one case report. No interactions between trazodone and digitalis have been reported. Until more is known, trazodone and digitalis-containing products should be used only under the direct supervision of a doctor trained in their use.