Pelvic area should be avoided if possible. Stage IV Hodgkin's Disease Disease has spread to organs outside the lymph system, such as liver, lung, or bone marrow. Chemotherapy combination regimens 2. Chemotherapy with total nodal irradiation or with radiation to places with large amounts of cancer 3. A clinical trial of bone marrow transplantation Relapsed or Recurrent Hodgkin's Disease Disease has recurred after treatment either in the same area or in another part of the body.
Treatment depends on where the disease comes back and the treatment received before.
If the previous treatment was radiation therapy without chemotherapy, then chemotherapy is the usual choice. If the previous treatment was chemotherapy without radiation therapy and the cancer comes back only in the lymph nodes, then the choice may be radiation therapy to the lymph nodes with or without more chemotherapy. If the disease comes back in more than one area, the patient may receive more chemotherapy or may want to consider a clinical trial of high doses of chemotherapy with bone marrow or peripheral stem cell transplantation. All rights reserved.