Many studies recommend a 10-15 minute break each hour to give yourself the recovery time you need. This needn't be a break from productive activities just a break from your keyboard. Exercises can help, too. Repeat several times. With arms outstretched in front of you, raise and lower your hands several times.
Variety is the key.
CTS occurs most frequently in workers whose motions are not only repetitious but are kept up for hours at a time. If you use a keyboard, structure your workdays to include a mix of activities each hour. For example, instead of typing all morning and filing all afternoon, mix typing and filing throughout the day. The most painful cases of CTS are those that have gone undetected or untreated over a long time. CTS can be caught easily in its early stages, however, and much of the pain and all of the disability avoided.