Burden of Suffering The most common age-related fractures are those of the distal forearm, vertebrae, and hip.
Vertebral fractures are the most common of the osteoporotic fractures.
Hip fractures are associated with more death, morbidity and medical costs than all other osteoporotic fractures combined. The incidence begins to rise after age 50 but rises dramatically after age 70. Treatment options for ERT include percutaneous estrogen, oral estrogen alone, or oral estrogen combined with progesterone. Outcomes Accuracy of tests. ERT-related outcomes include bone mineral loss, fractures, cardiovascular mortality and events, and breast and endometrial cancer.