Tamoxifen blocks the brain s use of estrogen, thus producing menopause-like symptoms.
Much publicity has been generated by various groups who believe that the anti-estrogenic effects of tamoxifen can be damaging to a woman s health. We certainly should never underestimate the effect of menopausal symptoms on a patient s quality of life, but our results are encouraging. Attribution to the Journal of Clinical Oncology is requested in all news coverage. The JCO News Digest is also distributed via email. Please let us know if you would like to be added to our email distribution list.