The first signs of the disease, which include lack of balance and slurred speech, usually occur during the first decade of life. Individuals with A-T are predisposed to leukemia and lymphoma and are extremely sensitive to radiation exposure. Many individuals with A-T have a weakened immune system, making them susceptible to recurrent respiratory infections. Children with A-T usually maintain normal or above normal intelligence. There is no cure for A-T and, currently, no way to slow the progression of the disease.
Treatment is symptomatic and supportive.
Physical and occupational therapy may help maintain flexibility. Speech therapy may also be needed. Gamma-globulin injections may be given to help supplement the weakened immune systems. High-dose vitamin regimes may also be used. The prognosis for individuals with A-T is poor.