According to Vedanta, our true nature is Divine. It is Sat, Chit, Ananda, or Absolute Existence, Consciousness, and Bliss. The cause of this distortion is said to be Cosmic Ignorance or Maya. Thereby, we become attached to body-mind complex and take it to be true.
Sense perception becomes the source of knowledge and sense pleasure the goal of life.
This worldly life is known as 'bound life'. In this situation, it is not possible for us to avoid sorrow, death, and miseries. Howsoever we may try, all the bodily pleasures and worldly knowledge including science and literature cannot make us happy. All these experiences are transitory. One day they are bond to vanish or lose their power.