The reason DataBin makes binary files, but stops short of producing an instant MIDI file from the data, is to give the ability to use the data for other parameters in addition to the obvious one of pitch. With creative mapping of the data, including using it to affect other parameters such as Volume, Modulation, Pan, etc., you will discover data sonification can produce highly listenable music - music that has extra layers of depth added by the data you have chosen to sonify. Other than that, there are very few limitations. If you read a file that is not text, or that has no line feed characters in it to separate the lines, it will appear as unreadable garbage or as an empty page. This is your clue that the data file format is not useable by DataBin.
Some data files are very large - up to several megabytes.
You can read and process these, but it will take extra time. Usually it will be better to break up the really large files into smaller ones, but there is no requirement to do so. DataBin treats the source data file as Read Only. That is, it never alters the source data file. If you make any changes, they only affect a temporary copy.