Introduction Introduction Our research is focused on the total synthesis of biologically active compounds and on the developement of new selective synthetic methodologies.
Special attention is paid to stereoselectivity problems as well as asymmetric synthesis.
In parallel with the synthesis of molecular targets, our group has become increasingly interested in the understanding of the mechanisms of action of these compounds, in order to conceive analogues with properties useful for the pharmaceutical and agrochemical industries. The first domain encompasses more specifically catalytic asymmetric oxidations, the asymmetric alkylation via organometallics, the asymmetric cycloadditions and cyclocondensations. Intramolecular Cycloadditions of Keteniminium Salts.