A rare complication of prolonged use of this and similar drugs is a condition called Pulmonary Hypertension. This condition is usually fatal and there is no effective treatment apart from heart-lung transplantation. However, these operations should only be performed at specialized centres. There are numerous medical complications as well. To view an example of the effects of weight loss, click here .
Smoking is another important factor.
However, smoking is now known to be a powerful addiction. There are a number of medical aids to quitting smoking such as nicotine replacement and drugs to decrease nicotine withdrawal symptoms. It takes persistence and determination to quit. Intervention is not usually required if a person drinks heavily on a few special occasions such as one's birthday. Again, treatment is more difficult in those who need it the most.