If probe molecules are complementary to molecules bound on the sheet, double-stranded DNAs will form, thus binding the probe to the sheet. Dot and slot blots, in which the sample is spotted directly on the nylon or nitrocellulose sheet without prior separation. Northern blots in which the molecules separated by electrophoresis are RNAs instead of DNAs. Colony lifts, in which the pattern of colonies on an agar plate is reproduced as a pattern of DNA spots on a nitrocellulose or nylon sheet. Plaque lifts, similar to colony lifts except the material lifted is from a phage plating.
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