Hyperthermia is receiving significant research interest, applicable to ovarian cancer. There are a large number of clinical trials which demonstrate that thermal effects can, in some cases, provide additional chemo-sensitization.
Thermal toxicities can be significant.
Clinical trials will continue investigation of this new technique. There are 5 different projects currently sponsored in hyperthermia. Links to descriptions of these projects are found here. Effective Clinical results demonstrated that hyperthermia enhances the effectiveness of chemotherapy. Results of ten studies were presented on the effectiveness of combined hyperthermia and chemotherapy treatment of a number of tumors, including breast cancer, brain tumors, ovarian cancer and colon cancer.