This treatment for male impotence called Pharmacologic Erection , has already enabled numerous patients to resume sexual intercourse without the need of surgery a penile prosthetic device or Erection Aid Devices. In erectile tissue both drugs mimic the action of natural neurotransmitter substances and cause both an increase in arterial blood inflow and a decrease in blood drainage. Thus injection of these agents into erectile tissue allows for a rigid penile erection to occur. The rigidity and duration of the erection may be dependent on the dose of the drug injected. 25 mg., and phentolamine .83 mg.
Some patients respond well to papaverine alone without phentolamine.
It has been our experience that the pharmacologic erection so achieved, may be improved in duration and rigidity with sexual stimulation. The drugs do not usually interfere with either ejaculation or orgasm. At present is a rational option for patients with neurologic impotence, whose penile tissue and blood supply are normal, but whose nerve to the penis is abnormal and some patients with mild vascular impotence. This program may be used to delay or defer indefinitely the more traditional treatment option by penile prosthesis implantation. The long term effects of repeated injections into the erectile tissue is unknown.