A cytochrome of the a type containing copper. The reduction of O 2 to water is accompanied by the extrusion of four protons from the intramitochondrial compartment.
Several bacteria appear to contain analogous oxidases.
E.F. Cytochrome oxidase. E.F. Cytochrome and cytochrome oxidase. Wainio, W.W., Eichel, B. and Gould, A. Ion and pH optimum for the oxidation of ferrocytochrome c by cytochrome c oxidase in air. Yonetani, T. Studies on cytochrome oxidase. Steady state properties.