St. Andrew's was built to provide a place of worship to local residents without making them go downtown. The current St. Andrew's was completed in 1951. St. Andrew's and Lenoir-Rhyne College have had their histories intertwine. Three of the four founders of Lenoir-Rhyne College helped charter St. Andrew's congregation. Many of LR's faculty have been members of St. Andrews and all ten of LR's Presidents have been members.
Students also have exclusive privileges at the church.
St. Andrew's and LR have both benefited from one another's existence.