A metaanalytic review of the data addressing the accuracy, sensitivity and specificity of CT as a mediastinal staging tool. Prospective Evaluation of Mediastinoscopy for Assessment of Carcinoma of the Lung. 53-56 One of the largest series addressing the role of routine mediastinoscopy in te evaluation of lung cancers. 1447-51 One of the rare series adressing T3 mediastinal disease as a separate group from other T3 tumors. The largest series on the topic.
Survival depends on the completeness of resection and on the nodal status.
Ginsberg RJ, et al. Lung Cancer Study Group. A Phase III prospective randomized cooperative group trial comparing lobectomy to segmentectomy and wedge resections in the management of T1N0 tumors. The experience of The Memorial Sloan Kettering Cancer Center when mediastinoscopy was not done routinely. A classic from The Toronto Thoracic Group demonstrating the value of routine mediastinoscopy in identifying a subset of N2 patients who are unlikely to benefit from resection alone.