Since all fatty acids enter systemic circulation from the liver, an oil like cetyl myristoleate would begin its systemic circulation from the liver also. It is speculated that cetyl myristoleate stimulates the production of immunoglobulins and series 1 and 3 prostaglandins, which could be one explanation for why cetyl myristoleate has such potent effects in auto-immune and inflammatory conditions. Clinical experience has shown that glucosamine sulfate is far superior when compared to cartilage extracts, such as sea cucumber, hydrolized bovine cartilage, and shark cartilage. This is due to the increased absorption and utilization of glucosamine sulfate compared to these sources of chrondroitin sulfates, which are very large molecules and difficult to digest. One of the reasons that glucosamine sulfate is more effective in rebuilding cartilage when compared to other sources of glucosamine, including the N-acetyl and hydrochloride forms, is that it provides bioavailable dietary sulfur.
Sulfur helps provide the protein links necessary for cartilage matrix repair.
MSM is found in most natural unprocessed foods. Because of its volatility, MSM is lost when fresh food is cooked, processed, or stored. As with any oil, cetyl myristoleate requires lipase to be digested. Lipases are pancreatic enzymes that play a key role in the digestion of fats ond fat soluble vitamins. If lipase is absent or deficient, cetyl myristoleate will be poorly absorbed, if at all.