Biopsy is performed if the clinical diagnosis is uncertain. Skin tags may be removed for cosmetic reasons by using scissors to clip the pedunculate lesions at the base. A dermatofibromatous lesion may occur, for example, after an insect bite on an extremity. A solitary lesion is most common, though multiple or eruptive histiocytomas have been reported. It may be necessary to perform a biopsy when the diagnosis is uncertain.
Treatment is necessary only for cosmetic reasons.
In the final phases of wound healing, fibroblasts degrade and produce bundles of collagen fibers. These bundles become thicker and are aligned along the lines of tension to which the tissues are exposed. As a result of these changes, wound tensile strength gradually increases. The resulting scar is relatively acellular and has fewer macrophages, blood vessels, and fibroblasts than the unwounded tissue. Scars may be normotrophic, atrophic, hypertrophic, or keloidal.