Mitochondrial morphology and distribution. Mitochondria are found distributed in the cell in an organised manner - often in order to meet the metabolic demands of the cell. Such arrangements are made by the presence of outer mitochondrial membrane proteins that somehow scaffold the organelle to the cell's cytoskeletal network. We are seeking to identify the components involved in this process and the interactions that take place. Protein complexes of the mitochondrial membranes.
Scientists now have access to the whole human genome database.
As part of this venture, it is our aim to define the population of proteins resident in the mitochondria. One approach is to identify the proteins that make up protein complexes of the mitochondria in an attempt to characterise their function more readily. Newly identified proteins will be further characterised based on their association with proteins of known function within the complex.