Scientific literature indicates SAMe has numerous health and medical applications.
On a cellular level, SAMe maintains mitochondrial function, prevents DNA mutations, and restores cellular membrane fluidity so that cell receptors are better able to bind hormones and other factors. SAMe has been studied extensively in Europe and is found to protect the liver against alcohol, drugs, and possibly chronic hepatitis. Perhaps most importantly, SAMe may be one of the most effective supplements in protecting against heart disease by destroying homocysteine. It is sold in Europe as a safe and effective anti-depressant and for combating a wide range of diseases related to aging such as liver disease and osteoporosis. SAMe may work better than antidepressant drugs with fewer side effects.