Usually the cofactor and substrate are found at the active site. The B group and C vitamins are water soluble. Pyridoxal phosphate Functions.
Structure is a complex organic acid.
Egg white contains avidin, a protein that binds biotin tightly, leading to problems on consumption of quantities of raw eggs. This binding is the basis for many enzyme assays through linking the analyte to biotin artificially. Note the partial flavin structure 1. DHF reductase is an essential enzyme in DNA biosynthesis. Co-A has an SH group.