So he pursues the pleasures and vanities of the world. Or someone forgets that El-Shaddai sees all things and knows all things. So he pursues sex outside of the marriage relationship. Or someone forgets that God is the husband of the widow and the father of the fatherless. So she becomes desperate, depressed, lonely, bitter, and suicidal.
Someone becomes sick.
Loved ones forget that God gives food to the hungry and sight to the blind. So they resort to desperate measures with quack doctors and pretend treatments. Problems and sin are always the result when our God is too small. So come to God. Ask to know Him.