Contrary to what many would have hoped for, there was no definitive regimen to recommend for people who have exhausted available treatment options. The good news is that, since hydroxyurea doesn't work on an HIV-specific enzyme, but rather on a human cellular enzyme, the possibility of HIV resistance developing is indeed minimal. However, watch for possible declines in white blood counts when this drug is used. Ultra Sensitive May Become Ultra Important Several studies validated the use of viral load as an important marker. Several ultra sensitive assays have already been developed, but an important question remains.
Today there are only eleven approved anti-HIV drugs.
I doubt that clinicians will do so in the near future. Pathogenetic Insights Evidence was presented to support the evolving notion that the earlier HIV is detected and treated, the better the prospect for long years of reasonable health. How late is too late remains to be discovered. A working group, consisting of representation from the CDC, NIH, FDA, HRSA and DHHS, anticipate releasing a preliminary statement on PEP this spring. There is also evidence of markedly improved survival rates from PML, an opportunistic brain infection, just from placing patients on triple therapy.