A chest roentgenogram showed mediastinal widening with involvement of the lung parenchyma by an infiltrative process. An abdominal CAT scan showed no lymphadenopathy. A biopsy of the left cervical lymph node was read as mixed cellularity Hodgkin's disease. Biopsy of the lung was positive for Hodgkin's. There was no disease below the diaphragm therefore this is a stage IIe,b.
Younger patients have a better prognosis than older patients.
We have already seen that the presence of symptoms correlates with a poor prognosis and that the histopathology is an important predictor of prognosis. A thirty-five year old man comes to you because of bone pain. He noticed a lump in his neck which increased in size since he first found it about three weeks ago. Lately he has been losing weight - 6 lbs. Liver function studies are grossly abnormal.