Pay attention to your suitcases, briefcase, laptop, and handbag during check-in. Alert thieves have been known to blithely scoop up the unattended, quickly handing purloined items off to fleet-footed accomplices. Ground floor rooms should be refused because they allow easy access to potential thieves. The especially security conscious will seek rooms far distant from stairwells on upper floors, believing that thieves or invaders will generally strike at rooms only within a certain distance of the planned escape route. If at all concerned about the walk to your room, ask that a security guard accompany you.
Thieves generally work during the day, when most guests are off doing other things.
Most thieves just want to grab loot and skedaddle and thus bend over backwards to avoid potential confrontation with the victim. By contrast, invaders generally work at night, at a time when most folks will be found in their rooms. The key to avoiding becoming the victim of such a crime is to not open your door to it.