No specific staging system exists for macroglobulinemia as it does for other diseases. However, most studies suggest that the level of the blood hemoglobin at diagnosis, your age, and the presence of weight loss have an impact on outcome. Your doctor will discuss with you aspects of your case and how that might affect the future. Treatment Symptomatic Waldenstr m's macroglobulinemia requires chemotherapy. Chemotherapy is the administration of medicines that specifically attack the abnormal cells to reduce the impact they have on the normal healthy bone marrow and reduce the level of the abnormal protein produced.
Treatment can be by pill or by vein.
Ongoing research into possible combinations of different medications are underway, as is research into the possibility of nonchemotherapy treatments for the disorder. If you have chemotherapy treatment, the level of the abnormal protein in your blood and urine will be closely monitored, and periodic bone marrows may be obtained to assess the number of abnormal lymphocytes in the bone marrow. This information helps your physician monitor your progress and make adjustments to your treatment. A drop in the level of the abnormal protein usually means the treatment is effective. A stable protein level indicates that the disease is stable.