Test code links throughout this Guide refer to the corresponding test in the User's Guide. The muscle relaxant succinylcholine is commonly used during anesthesia and will not be rapidly metabolized in these patients.
True cholinesterase is found in RBCs and nervous tissues.
Pseudocholinesterase is found in the plasma. True cholinesterase is responsible for inactivating the acetylcholine produced at the neuromuscular junction during neurotransmission. This is necessary to allow for subsequent repolarization of the nerve ending. True cholinesterase levels and activity are altered in organophosphate insecticide poisoning. Total whole blood cholinesterase may be used as a screening test for acute and chronic exposure.