Two different types of macular dystrophy exist based on the absence or presence of keratan sulfate within the corneal stroma. Light microscopy reveals glycosaminoglycan deposits within stromal keratocytes. Deposits in macular dystrophy are composed of glycosaminoglycans, which stain with Alcian blue and colloidal iron. Light microscopy demonstrates glycosaminoglycan deposits within stromal keratocytes. Two different types of macular dystrophy are based on the absence or presence of keratan sulfate within the corneal stroma.
Sunglasses are often helpful for severe glare symptoms.
PTK works best when the opacities are superficial. The excimer laser removes superficial corneal opacities, smoothens the corneal surface, and allows the epithelium to re-adhere more tightly. If visual acuity drops and opacities are deep, lamellar or full-thickness corneal transplantation can be performed. Although the success rate for corneal transplantation is very high, macular dystrophy deposits can recur with time. Lubrication also may help prevent further corneal erosions.