Return to top Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Compazine. Return to top Do not take Compazine if you are sensitive to or have ever had an allergic reaction to prochlorperazine or other phenothiazine drugs such as Thorazine, Prolixin, Triavil, Mellaril, or Stelazine. Never take large amounts of alcohol, barbiturates, or narcotics when taking Compazine.
Serious problems can result.
If you suddenly stop taking Compazine, you may experience a change in appetite, dizziness, nausea, vomiting, and tremors. Follow your doctor's instructions closely when discontinuing this drug. Make sure the doctor knows if you are being treated for a brain tumor, intestinal blockage, heart disease, glaucoma, or an abnormal blood condition such as leukemia, or if you are exposed to extreme heat or pesticides. This drug may impair your ability to drive a car or operate potentially dangerous machinery. Do not participate in any activities that require full alertness if you are unsure about your ability.