Studies have shown that cisapride can heal esophageal inflammation.
Side effects are minimal and include headaches, abdominal cramping and diarrhea.
In patients who are on a variety of antibiotics, antifungal drugs and anti-histamines with cisapride abnormal heart rhythms can occur. Abnormal heart rhythms and palpitations can also occur in patients with underlying heart disease. Cisapride should not be used in these patients. Domperidone is not yet available in the United States but I was told by the pharmaceutical company that it will be marketed soon under the name Motilium. It is a peripheral dopamine antagonist.