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Tamoxifen blocks the brain s use of estrogen, thus producing menopause-like symptoms.
This is good news for women at high risk of breast cancer who are considering using tamoxifen, said Lesley Fallowfield, PhD, of the University of Sussex. Much publicity has been generated by various groups who believe that the anti-estrogenic effects of tamoxifen can be damaging to a woman s health. We certainly should never underestimate the effect of menopausal symptoms on a patient s quality of life, but our results are encouraging. This explains why its overall effects on things like sexual activity may be more balanced than once thought she said.