Navigation can be difficult due to submerged mud flats, a meandering unmarked channel, and shallow water tidal changes. Boat launching is not permitted from the refuge. A public launching ramp is available at Shorter's Wharf. All fishing and crab lines must be attended. No special refuge permits are required, however, a valid State sport fishing license is required to fish in the Blackwater River and the Little Blackwater River.
State regulations apply while fishing and crabbing on the refuge.
The Little Blackwater is a very popular spot for the spring run of the white perch. Other species available in the waters of the refuge are carp, blue gill and pickerel. Highway Administration regulations regarding fishing from bridges since regulations are subject to change. Key Wallace Drive is often under tidal water and has no road shoulders on which to park near the bridge. Although there are no parking areas, visitors with small boats or canoes often carry them from their vehicles to the water near the bridges.