C. Reactions of Phenols as Acids 1. Effect of the aromatic ring on acidity 2. D. Other Reactions of the O-H Group in Phenols 1. Phenols in the Williamson Synthesis- Reaction of phenols with NaOH or KOH forms a nucleophilic phenoxide ion. These phenoxide salts may be used in the Williamson Synthesis 3.
Special conditions are necessary for monosubstitution.