Nephritis is a general term for inflammation of the kidneys. There are several hereditary forms of nephritis. The disorder causes chronic glomerulonephritis with destruction of the glomeruli. The cause of AS is a mutation in a gene for collagen. The disorder is uncommon, affecting about 2 out of 10,000 people.
Treatment requires medication, and often, kidney transplant.
This is the same type of information that is available to physicians and other health care professionals. Clinical aspects, pathology, molecular biology and extracellular matrix studies. 2000 Alport syndrome. An inherited disorder of renal, ocular, and cochlear basement membranes. 1999 Alport syndrome.