It may be linked to hereditary tendencies, and typical gene abnormalities are seen in persons with the tumor. Neuroblastoma is most commonly diagnosed in children before age 5. The disorder occurs in approximately 1 out of 100,000 people. It is slightly more common in boys. Pepper's syndrome is a neuroblastoma that originates in the adrenal gland and usually metastasizes to the liver.
Symptoms vary depending on the site of the tumor .
Signs vary depending on the location of the tumor . The liver may be enlarged if the tumor has spread to the liver. Adrenal gland tumor often causes high blood pressure and a fast heart rate . CBC showing anemia or other abnormality. Surgery is usually indicated.