The cause is unknown, but may be related to a dysfunction of the immune system . Typically seen in elderly individuals, bullous pemphigoid may manifest as large fluid-filled blisters located on the arms, legs, or trunk. Itching, mouth sores, and bleeding gums may also be seen. The blisters tend to remit and recur.
Topical corticosteroids are the treatment of choice.
Other medications such as chemotherapeutic agents and antibiotics have also been used in select cases. Complications include bacterial infection of the blisters.