They are usually more molted than native species and have more warts. The skin on the dorsum is tuberculate and that of the venter is granular. They possess a skin fold which extends from the eye back to the tympanum . Cuban trefrogs have no stripe running through or below their eyes. They have a distinct tarsal fold extending the full length of the tarsus.
Tadpoles have a rounded body.
Cuban treefrogs are active mainly at night. During the day they hide in moist areas such as cisterns, drains, cellars, and on the trunks of plants. They thrive in altered habitats being most abundant around ornamental fish ponds and well lighted patios where they are often found on walls, glass windows, porches and potted plants waiting for insects. These were 1 specimen collected June 1951 in a low lying field of Miami, at the intersection of Red Road and NW 7th St., and 7 more specimens collected the 9th of July at a rock pit also in Miami, located at the intersection of NW 27th Ave. The Cuban treefrog is currently a common species which adapts quickly to living around homes.