The choice of drug depends on the clinical circumstances, but one broad-spectrum antibiotic should be administered in full therapeutic doses, parenterally if possible, and preferably intravenously, and commenced at the earliest possible level of medical care. The choice of antibiotic will depend upon many factors, including the specific threat or threats, evidence or suspicion of natural antibiotic resistance among strains, and the ease with which drug resistance can be artificially engineered. Where applicable, specific guidelines are included in Annex B . Other antiviral drugs, such as amantadine, acyclovir, and azidothymidine, are restricted in their therapeutic spectrum to single virus families, and thus have little application as non-specific antiviral. Where applicable, specific guidelines are included in Annex B .
Specific antitoxins are available for certain conditions.
Where applicable, specific guidelines are included in Annex B . No broad-spectrum antitoxins currently exist. Use of Barrier Techniques. Potential Biological Hazards. In particular, materials soiled by patient secrets and excreta, as well as samples for diagnostic laboratory study, must be clearly identified as hazardous and appropriate handling procedures applied.