In this paper the question is analyzed, how it is possible to reconstruct classical space-time from the net of local observables of a quantum field theory. To this end different aspects of space-time structure are considered separately.
Special attention is drawn to the topological and the causal structure of space-time.
Within the scope of causality the differences between causal spaces introduced by Kronheimer and Penrose and causal disjointness relations used in algebraic quantum field theory are considered.