Visual problems progressing to blindness may be the first symptom. Genetic counseling is recommended for prospective parents with a family history of Krabbe disease. Carrier states may be recognized by decreased galactocerebroside beta-galactosidase levels in their white blood cells or skin fibroblasts. Prenatal diagnosis is possible by measuring galactocerebroside beta-galactosidase levels in cultured amniotic fluid cells or from cultured chorionic villi cells. There may be signs of deafness .
Treatment lies in prevention.
The outcome is likely to be poor. Seizures and change in muscle tone are emergency symptoms, as is a loss of consciousness or abnormal posturing . The information provided herein should not be used for diagnosis or treatment of any medical condition. A licensed physician should be consulted for diagnosis and treatment of any and all medical conditions. Inc. Any duplication or distribution of the information contained herein is strictly prohibited.