Changes caused by the influence of cathodic polarization were not statistically probable. A conclusion about the possibility of the use of anodic polarization in influencing cholinergic processes in the higher parts of the central nervous system is made. In addition, the thrombocyte ultrastructure of venous blood of 7 patients suffering from MI was studied. It was revealed that thrombocytes adhere to swollen or injured vascular endothelia and form aggregates which lead to microhaemodynamic disturbances. Adhesion of thrombocyte aggregates and microthrombi to the injured arteriole wall causes proliferation of encompassing connective tissue.
Thrombocytes play a decisive role in thrombogenesis.
Thrombocyte activation by connective tissue elements of the arteriole wall or neutrophil leukocytes triggers off this process. Thrombocyte degranulation leads to arteriole vasoconstriction and damage, as well as to blood stagnation and coagulation in the region beneath the obturation. By preventing thrombocyte aggregation and thrombi formation, antithrombocyte and anticoagulant drugs reduce surrounding connective tissue proliferation as well as the narrowing and obliteration of arteriole lumen. Light, electron and immunofluorescence microscopy was used. FGN in most cases was caused by antibiotics and nonsteroidal anti-inflammatory drugs.