I frequently use antidepresants, with no problems. Remember that depression is a chemical derrangement in the brain conductors, and is almost always aggravated by the INF.Many patients may need analgesics and ocass. You need to be followed closely for anemia and neutropenia, that can be severe. Finally, you cannot assume that all your symtoms are related to the treatment. For example, rectal bleeding and anal pain is a different problem,that should be evaluated.
Some patients draw benefits of support groups.
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