Most physicians recommend one to two weeks for a washout depending on the severity of the depression. My wife is currently on Paxil and has tried twice to wean herself unsuccessfully. I would appreciate any help you can give us. Serzone is a completely different drug than Paxil. It seems to be less effective, but has much less effect on sleep and decreasing sex drive.
Some patients have less weight gain as well.
Common side effects include dry mouth, nausea, constipation, blurred vision, dizziness, confusion and sleepiness. Headache, decreased appetite, diarrhea, etc., also occur, but less frequently. My patients generally tolerate it well if started low and increased slowly. It does seem to affect sex drive less intensely than Paxil. I'm wondering if there's a medication that will relieve this symptom.