Once the TSH is adequately lowered to 1.0 or 0.50, and, once a patient has gotten symptom relief with an antidepressant, if necessary, and still has residual fatigue, or anergia, then a psychostimulant trial is offered as an additional treatment. Stimulants are very safe, compared to many non-controlled drugs. Carbohydrate binging is associated with some depressive syndromes. L-tryptophan is the precursor to serotonin, known to us now as a major neurotransmitter in the brain, particularly in regards to mood and sleep functions. The antidepressants used these days, although worlds better than their predecessors, cause some side effects.
Weight gain is one commonly seen with a number of the antidepressants prescribed currently.
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