We are conducting studies to determine the role of inflammatory mediators and adhesion molecules in the vasculature of the heart and lung and their role in inducing ischaemia-reperfusion injury. Studies are also underway to investigate the protective properties of anaesthetic agents during the ischaemia-reperfusion period during cardiac surgery. Hypothermic preservation of isolated rat lungs in modified bicarbonate buffer, EuroCollins solution or St Thomas Hospital cardioplegic solution. Ischemic preconditioning in immature myocardium. A clinical comparative study between crystalloid and blood-based St Thomas Hospital cardioplegic solution.
Theophylline improves functional recovery of isolated rat lungs following hypothermic preservation.
New developments in cardioprotection. Polarization and Myocardial Protection. Ischaemic preconditioning enhances recovery of isolated rat lungs following hypothermic preservation. A comparison of four phosphodiesterase inhibitors of differing isoenzyme selectivity added to St Thomas Hospital cardioplegic solution used for long-term hypothermic preservation of rat lungs. An experimental study.