Free radical generation superoxide, nitric oxide, peroxynitrite, endocytosis, exocytosis, nitrite reductase, nitrate reductase, human milk, bovine milk, antibacterial activity, flow cytometry, confocal microscopy, Cell biology, Endothelium, Endothelial cell isolation and culture. Millar, T., Stevens, CR, and Blake, DR. 1997. Xanthine oxidase can generate nitric oxide from nitrate in ischaemia. Human endothelial cells can bind xanthine oxidase as assessed by flow cytometry. A role in nitrate tolerance.
Xanthine oxidase generates nitric oxide from nitrates and nitrite in hypoxia.
Xanthine oxidoreductase catalyses the reduction of nitrates and nitrite to nitric oxide under hypoxic conditions. O'Byrne, S., Shirodaria, C, Millar, T, Stevens, C, Blake, D, and Benjamin, N. 2000. Inhibition of platelet aggregation with glyceryl trinitrate and xanthine oxidoreductase. Winrow, V., Millar, TM, and Blake, DR. 1997. Redox modulation of haem oxygenase-1 transcription in endothelial cells.