Sometimes when hardening of the arteries effects the vessels to the kidneys it can lead to high blood pressure. Since the kidneys get a lower amount of blood flow, it is tricked into thinking that the body's blood pressure is low and causes the blood pressure to increase causing very high blood pressure for the rest of the body. Generally, PVD would not be the reason for muscle twitching. It is more likely due to other reasons. You should consult with your primary care doctor if this is a problem.
Veins normally allow blood to go in one direction by having valves in the system.
Varicose veins can also sometimes be a result of an old DVT or blood clot in the past leading to these leaky valves. More often, varicose veins are of cosmetic concern rather than a cause for real vascular problems. There are, however, patients with varicose veins who are truly symptomatic having associated pain, heaviness, and associated leg swelling and discomfort. Surgery to the heart is usually done by a surgeon who has had specialty training in treating heart and lung problems whereas surgery done to blood vessels in the periphery is often done by surgeons trained in taking care of peripheral vascular disease. There are occasionally surgeons trained to do both.