Play time continually decreases. When ferrets are severely hypoglycemic they may become very weak and show signs of muscle weakness particularly in the hind end. Sometimes they will be sitting still and appear to be staring off into space for many seconds - you might notice some bobbing of the head. Continual weight loss and dull shabby coat. Obviously, the fifth warning sign is the most severe.
Seizures happen when the body is deprived of sugar for too long a period of time.
Typical seizures consist of the ferret laying outstretched on its side, excessive drooling to foaming at the mouth, twitching and shaking and may be unresponsive to outside stimulations. If you think your ferret is having a seizure from low blood sugar, you must give something sugary immediately to raise the blood sugar level. A seizuring ferret will not be able to swallow liquids so it would be best to rub something thicker such as Karo syrup, honey or maple syrup on the ferret's gums with a q-tip. He or she has additional injectable medications that may help to stop the seizure. Usually applying the sugary substance to the gums will temporarily control or eliminate the seizure activity.