Left foot only just before the ball of the foot down from the toe next to the pinky. Exercise, proper diet and releasing stress. Salt hardens the arterial wall. Cholesterol imbalances or excesses corrode the inside of the arterial wall restricting blood flow. High Blood Pressure in time can weaken and enlarge the heart and weaken the arterial wall.
Tobacco causes the small and large blood vessels to constrict which adds stress to the heart.
Not enough oxygen from the lungs deprives all tissue including the heart. Being overweight puts more demands on the heart. The strep germ left gone too long in the body can cause Rheumatic fever and severely weaken and enlarge the heart. Difficulty in breathing. Swollen extremities, blue lips, fingernails and skin.