The information on this site is subject to a disclaimer and a copyright notice . The definition of the SCF lists is given in the Appendix. The opinion of the Committee on each of the substances is shown in the same table.
Toxicity profiles similar to methaldehyde.
The reports on nasal carcinogenicity after inhalation were considered without relevance for effects from oral intake of smaller doses. In first instance, in vivo mouse bone marrow micronucleus assay or rodent bone marrow metaphase analysis assay. The applicant did not demonstrate the absence of potential for bioaccumulation. The SCF concluded that due to its restricted use, the exposure will be minimal and therefore the question of potential bioaccumulation is not considered relevant. Since high migration into fat has been demonstrated, the SCF recommends that the Commission take the necessary measures, so that the restriction proposed is not exceeded.