In discovery chemistry, you cannot afford to be limited by your tools. If you need to use a wide range of synthetic methodology, be sure your synthesizer will support you. The Trident system is reliable under the demanding conditions that are a part of small molecule discovery. Both solution and solid phase chemistry Solid phase chemistry has provided great advantages for parallel synthesis and purification, but you may not always be able to transfer your solution phase methods to solid phase. Plus, there are new chemical methods for speeding solution phase purification.
Trident works well for both solution phase and solid phase synthesis.
Each reaction vessel is sealed tight and no septa are used for delivery. Teflon tubes fit tightly into these ports to accurately deliver solvents and reagents. In validation experiments , no cross-over contamination has been detected between vessels. Experiments show that the delivery is reliable even with corrosive, volatile, and viscous reagents. Variable agitation Set the agitation to the appropriate level for your reaction.