Book big-ticket items like travel, accommodations and vehicle rentals well in advance with a travel agent to ensure having choices. Expect that some plans awry. Getting lost can lead to memorable experiences if you remain calm. If you can't carry all your bags, you're taking too much. Leave the cell phone, pager and laptop at home.
Vacations are about detaching from work.
Don't overbook your itinerary. Everything takes longer in a strange place. Allow time for vegging out, even on an active vacation. Research prices at your destination, especially if going abroad. Ask your travel agent.