Radiation therapy is used for incomplete excision, post-op recurrences, and nonsurgical candidates. Most commonly squamous cell cancer, arising from the turbinates, followed by nasal septum, floor, and vestibule with frequent involvement of lymph nodes. A destructive lesion with extension through palate and facial soft tissues. It is usually localized to airway and upper aerodigestive tract and may remain histologically benign or evolve into polymorphic reticulosis. Impairment of delayed hypersensitivity often seen.
Treatment is with radiation therapy.
This is a systemic disease usually occurring with abnormal findings on chest x-ray. Biopsy reveals noncaseating epithelioid granulomas in the lymphoreticular tissue. Treatment includes surgery, systemic steroids, and possibly methotrexate.