It is always associated with one of several uncommon tumors of the immunologic or blood systems. Pemphigoid was differentiated from pemphigus in the 1950s. It commonly involves large, itchy areas, large blisters and hive-like rashes. Treatment for pemphigoid involves blocking the inflammation factors. There are numerous medicines which are effective.
Treatment usually includes steroids.
Tetracycline and niacinamide may work instead of steroids in mild cases. It is not life-threatening in most cases. It needs to be treated aggressively with steroids. Dr. Anhalt's second presentation was on the treatment of pemphigus. Some of the problems in treating pemphigus arise from a lack of scientific studies due to the small patient populations which preclude traditional double-blind crossover trials.