Use Leave No Trace guidelines to minimize your impacts. Backcountry permits for camping and hiking are not required, however there are rules and regulations governing one's behavior in all national park areas. Become familiar with them. Resist the urge to take, shape or alter the wilderness around you. A further caution then, take it upon yourself to be extremely knowledgeable and prepared.
Weather can often be uncooperative.
Adventures such as these demand self-sufficiency and advanced backcountry skills. Assistance maybe days away. Travelers should also be prepared for the possibility of inclement weather delaying scheduled pick-up, again by perhaps several days. There are rivers to ford, mires to avoid, weather to sit out and experiences of a life time to be found here. As varied as Lake Clark National Park and Preserve is, so is its hiking.