Discovery of fold descriptions Protein shape is usually described at various levels of abstraction. At the lower levels each family of proteins contains members with high sequence similarity. At the most abstract level folds describe proteins which have similar overall shape but are very different at the sequence level. The lack of understanding of shape determination has made protein fold prediction particularly hard. However, it is intriguing that although there are around 300 known folds, around half of all known proteins are members of the 20 most populated folds.
Science is an activity of human societies.
It is our belief that computer-based scientific discovery must support strong integration into existing the social environment of human scientific communities. The discovered knowledge must add to and build on existing science. We believe that the ability to incorporate background knowledge and re-use learned knowledge together with the comprehensibility of the hypotheses, have marked out ILP as a particularly effective approach for scientific knowledge discovery. Bibliography 1 I. Bratko and S. Muggleton. Applications of inductive logic programming.