In the case of major limb length discrepancies, serial radiographic studies including but not limited to scanograms, orthoroentgenograms, and CT scans for measurement of limb length are necessary. Clinical measurements can only guarantee measurement within 0.5-1.0 cm, whereas radiographic exams can determine exact differences to within 0.1 cm. These studies help to determine how fast a limb is growing and may help in determining proper timing for limb length equalization procedures. Prenatal diagnosis by ultrasound has been reported. Management of this syndrome can be divided into medical and surgical interventions.
Treatment is conservative and symptomatic.
Compression garments are indicated for chronic venous insufficiency, lymphedema, recurrent cellulitis and recurrent bleeding from capillary or venous malformations of the extremity. The compression garment may also protect the limb from trauma. Intermittent pneumatic compression pumps may also provide benefit. However, in some patients with absent or hypoplastic deep venous systems, elastic compression may increase venous stasis and cause discomfort. Cellulitis and thrombophlebitis can be managed with analgesics, elevation, antibiotics and corticosteroids.