A combination of faculty lectures and presentations by participating students. Advanced eukaryotic molecular genetics. Required for second year Genetics and Development students. Advanced treatment of the principles and methods of the molecular biology of eukaryotes, emphasizing the organization, expression, and evolution of eukaryotic genes. Topics include reassociation and hybridization kinetics, gene numbers, genomic organization at the DNA level, mechanisms of recombination, transposable elements, DNA rearrangements, gene amplification, oncogenes, recombinant DNA techniques, transcription and RNA splicing.
Students participate in discussions of problem sets on the current literature.
Cellular and molecular biology of cancer. I. Weinstein and staff. Required for students on the cancer training grant. Open to all students. An integrated and critical review of cancer biology, emphasizing recent research.