Simin Liu, M.D., Sc.D., and colleagues from Brigham and Women's Hospital and Harvard Medical School conducted the study, which included 75,521 U.S. women aged 38 to 63 years without previous diagnosis of diabetes mellitus, coronary heart disease, or stroke in 1984, the year the study began. The percentage remained essentially constant, even with adjustment for CVD risk factors, including saturated fat and transfatty acids intake. The percentage also remained consistent among subgroups of women who never smoked, did not drink alcohol, did not regularly exercise, or who did not use postmenopausal hormones.
Stroke is a leading cause of serious disability and death in women.
In the United States, approximately 600,000 cases of stroke accounted for 160,000 deaths in 1997. At all ages, more women than men die of stroke. Survey data indicated that most grains consumed are processed and refined, and average intake of whole grains was only one half serving per day. Barlow and her colleagues found that the 24 genes differed widely in their expression level after the seizure. For example, the mice resistant to post-seizure neuronal death produced less of the proteins that form ion channels, important structures that allow nerve cells to send messages from one cell to another.