The amino acid Arginine, in addition to causing the release of growth hormone, increases nitric oxide levels in a way similar to how Viagra works. Any redundancy of supplementation places a load on the liver, and an energy drain can result. Too much firepower can overtax the liver and make the body sluggish. Too little stimulation can have the same effect. The recommended dosage must be tailored to fit each individual depending on age, body weight and overall health.
Some experimentation is usually necessary to discover the optimal dosage.
As age increases, metabolic rate and detoxifying ability are lessened, so a lower dosage is required. Increased body weight usually requires a larger dose. General health level is also an important factor when considering the right dosage. The healthier a person is, the larger the amount that can be tolerated. Nutritional supplements that support the Endocrine Axis should be taken in the morning with a meal, to prevent overstimulation and possible insomnia.