Creatine seems to be well studied in scientific research. Scientific evidence supporting creatine is there, but while some very good results have been reported, like a 20 lbs body weight gain in 6 weeks and strength increases, others have reported no significant gains whatsoever while taking the supplement. Like all supplements, supplementing creatine is useless if your body already has enough of it. Further supplementation is then not needed and just a waste of money. If however, you do not have the optimal levels of creatine in your muscle cells, then supplementation is a good idea which can really enhance your training.
Some people get minimal or no effect from creatine.
If you take creatine monohydrate and don't notice any results in about 2 weeks it's a good bet that you're one of these people. Creatinine is usually a sign of kidney problems, but it is harmless as a side effect of creatine supplements. In other words, this is a false positive result. I ended up consulting with my personal physician and taking another blood test in order to clear this up. This is especially important to help the kidneys deal with the abundance of nutrients that bodybuilders seek to keep in their blood.