Serum ASO may be elevated. Serum complement levels usually decrease. Kidney biopsy confirms post-streptococcal glomerulonephritis, but biopsy is not usually necessary. The results of an anti-DNAase B test may be abnormal. There is no specific treatment for post-streptococcal glomerulonephritis.
Treatment is focused on relief of symptoms.
Antibiotics, such as penicillin, should be used to destroy any streptococcal bacteria that remain in the body. Antihypertensive medications and diuretic medications may be needed to control swelling and high blood pressure . Corticosteroids and other anti-inflammatory medications are generally not effective. Dietary salt restriction may be necessary to control swelling and high blood pressure. In a minority of adults, it may progress to chronic renal failure .