Local recurrences were operated on in 13 patients. Extension to the vena cava was not considered as a contra indication even in cases of massive extension. In this group, some patients may have benefited from mitotane. Further studies are mandatory to appreciate the benefit of adjuvant therapy with mitotane and palliative chemotherapy. Adrenocortical cancers are relatively rare endocrine tumors that usually present when hormonally active or after they have become large and metastasis has occurred.
Surgical removal remains the only form of therapy proven to prolong survival.
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