In fact, any coherent explanation will be taken as non-sensical and sensible at the same time, as the disease forces a major reshuffling of idea bases every once in a while in the patient. At this point, the patient is prone to believing anything. The amount of meaning that can be conveyed to the patient is enormous. In fact, the situation is very similar to a gedanken experiment, where a normal sane person comes into contact with a source that explains everything. The explanations and meanings do not have any coherent meaning to the outside world, yet to the patient are very important.
Some patients stop speaking altogether.
Others isolate themselves and don't care about anything. Others become monks or priests. There is a huge percentage of priests coming from this realm, without realizing that they in fact suffer from a very serious disease. They take it as 'the voice of God'. From the patient's perspective, there is a huge conspiracy on them.