Cell-free virus would likely be reabsorbed with the cerebrospinal fluid back into blood. These drain directly into the cervical nodes. This provides a pathway by which virus or infected immune cells could travel directly from the CNS to lymph nodes without having to be exposed to blood-borne antivirals. References Use the Back button in your browser to continue reading the article. J Neuropathol Exp Neurol 54, 497-503.
Serum proteins bypass the blood-brain barrier for extracellular entry to the central nervous system.
Morphological aspects of the barriers. Sensory circumventricular organs and brain homeostatic pathways. J Acquir Immune Defic Syndr Hum Retrovirol 9, 99. Immunobiology of the blood-brain barrier. J Neurovirol 5, 570-578.