Signs and symptoms of acute exposure to endrin may be severe and include headache, dizziness, deafness, agitation, nervousness, tremors, frothing of the mouth, seizures, and coma. Convulsive episodes may alternate with periods of severe central nervous system depression. Nausea, vomiting, and diarrhea are common. Respiratory depression may lead to respiratory arrest. Contact with the skin, eyes, and mucous membranes may result in redness and irritation.
Victims often have an elevated temperature.
Acute exposure to endrin may require decontamination and life support for the victims. Emergency personnel should wear protective clothing appropriate to the type and degree of contamination. Rescue vehicles should carry supplies such as plastic sheeting and disposable plastic bags to assist in preventing spread of contamination. Move victims to fresh air. Emergency personnel should avoid self-exposure to endrin.