It is more prevalent in men and is highly associated with the HLA-B27 genotype. The age of onset is between 20 and 40 years. It is usually acute in onset, and symptoms include pain, photophobia, and redness. Recurrent episodes may eventually lead to cataracts and glaucoma.
Treatment consists of topical and oral steroids.
Periocular steroid injections, cycloplegia and mydriatics may be used. Phenylbutazone can be substituted when indomethacin is not effective.