Phase III Researchers compare the results of a new treatment with the results of a standard treatment. Phase III trials seek to determine whether the standard or the experimental treatment group has better survival rates or fewer side effects. Phase III trials may include hundreds of people nationwide with a particular type of cancer. People are often assigned randomly to receive either the new treatment or the standard treatment, thereby avoiding bias in the results. The goal of clinical trials is to establish the safety and effectiveness of treatments.
Treatments proven effective during trials often become new standard treatments.
Comparing similar groups of people taking different treatments for the same type and stage of cancer helps establish that any benefits are due to the treatment rather than chance or other factors. By comparing standard treatments and new treatments, Phase III trials ensure that no one in the study is left untreated. Protocol Clinical trials follow a scientific protocol or action plan. The protocol details what will be done in the study and why. It also outlines who and how many people will take part, the type and frequency of tests, and the treatment plan.