A positive crossmatch is a contraindication to transplant. It is performed by mixing a very small amount of the patient's serum with a small amount of cells from 60 different individuals, in separate tests. Remember the HLA are on the surface of these cells. The PRA is calculated for each monthly serum sample. In addition to determining how much or how little PRA a patient has, we need to know how specific the antibody is.
Some patients have one or two antibody specificities, while others have numerous specificities.
HLA typing Crossmatch Antibody Screening DNA typing Immunosuppressive drug monitoring. Cell surface structures recognized as foreign by one individual when exposed to tissue of another individual. These effects are Genistein concentration-specific, the latter effect, and especially the transition of normal lymphocytes from the quiescent state to actively prolifering cells, was particularly sensitive to the action of Genistein. In this regard, the possible therapeutic value of Genistein may be enhanced by very low toxicity in vitro. The aim of this study is to correlate characteristic changes in the expression of differentiation and activation markers on the surface of peripheral blood lymphocytes from kidney transplant recipients during the course of anti-rejection therapy.