Neuroblastoma is most commonly diagnosed in children before age 5. The disorder occurs in approximately 1 out of 100,000 people. It is slightly more common in boys. Pepper's syndrome is a neuroblastoma that originates in the adrenal gland and usually metastasizes to the liver. Symptoms vary depending on the site of the tumor .
Signs vary depending on the location of the tumor .
The liver may be enlarged if the tumor has spread to the liver. Adrenal gland tumor often causes high blood pressure and a fast heart rate . CBC showing anemia or other abnormality. Surgery is usually indicated. This includes removal of all or part of the tumor and surrounding lymph nodes.