This causes further cartilage destruction. Bones begin to thicken or change shape and joint spaces narrow, causing inflammation and pain. In severe cases, all of the cushioning cartilage may be destroyed. Bone comes in direct contact with other bone, causing pain and limiting movement in the joint. Symptoms you may notice Pain is the major symptom of osteoarthritis and cartilage loss.
Some people also experience swelling and inflammation.
Others may feel no pain, even though X-rays show joint damage. Doctors find that the amount of joint damage isn't always connected to the amount of pain a person feels. Osteoarthritis usually affects the joints of the knees, hips, hands, neck, and lower back. Laboratory tests may rule out other diseases that call for aggressive treatment, such as infectious arthritis or rheumatoid arthritis . But some conditions can increase your risk of getting it earlier or making it worse.