Your exposure to oestrogen may also have an effect on your risk of developing breast cancer as it attaches itself to receptors in the breast on the surface of cells and stimulates them to divide in anticipation of producing milk, it is this division of cells that is thought to cause the risk. The first two oestrogens, E1 and E2, are the most powerful they easily relieve menopausal symptoms and help the body stay healthy, however they may also be the cause of an increased risk of breast cancer and other side effects if they are given in high doses over a long period of time. The third form of oestrogen, E3 is made from a combination of E1 and E2 and is less potent. Therefore Hormone Replacement Therapy made from E3 may be more appropriate for those women who are concerned about taking HRT for health reasons. There is no standard as far as the production of oestrogen naturally is concerned.
Women vary in their needs during their lifetime.
When a woman has a hysterectomy that removes her ovaries, she will no longer produce oestrogen from them. She will continue to produce oestrogen in the adrenal gland and in fatty tissues but these are only very small amounts and are not enough even to prevent climacteric symptoms . Oestrogen is the main form of Hormone Replacement Therapy that is taken by women who have had a hysterectomy. It can be taken in many different forms and although called natural, it is manufactured.