Another recommended loud music with lots of thumping bass. DON'T try the 1812 Overture. When the skunks are gone, seal up the entrance securely as described above. I've seen skunks re-open old dens which are poorly sealed. A barrier can also include a wire skirt at ground level extending at least 12 inches outward.
Skunks mate in Late Feb through Early March.
Young skunks may remain in the den from Late April to Early August. Be sure all animals are out before sealing entrance . Skunk in a window well, cellar, or hole in the ground Carefully lower a cleated board into the hole to allow it to climb out and escape. Skunks will eat bees and damage beehives. I read that they're apparently not bothered by bee stings.