Some are quite specialized. All are designed to seal some gap or space where energy is leaking away most often around doors and windows. Since there are so many choices, I recommend the following for ease of installation and durability. First however, there are a couple of things to keep in mind when applying weatherstripping to doors and windows.
Wooden thresholds add warmth in appearance as well, but are a bit more costly than aluminum.
Bronze and stainless steel are used but are considerably more expensive. Choose your threshold to match your floor. And take great care in measuring for a replacement. Both wood and aluminum are sold in different lengths for standard door widths. Replacing a Wooden Threshold 1.