Using dynamic NMR to understand the nature of the intermediate structures on the folding and unfolding pathways and to examine proteins that are misfolded causing aberrations and diseases. Requires Ph.D. or equivalent level degree in Chemistry with focus in Fluorine NMR Spectroscopy.
Several openings exist for qualified postdoctoral fellows in the areas outlined below.
As a co-receptor for SIRPa, IAP functions as a marker of self to control and regulate phagocytosis by macrophages in a variety of settings of significance for host defense and inflammation. We are seeking to understand the molecular mechanisms of CD36 action in endothelial cells, macrophages and model cell lines as well as the structure-function relationships of CD36, an unusual membrane protein in which both the N and C termini are intracytoplasmic and the bulk of the protein is extracellular. Please attach a current CV and a brief statement of research background and interests. A good command of written and spoken English is required. Postdoctoral positions available to study the structures of proteins involved in DNA replication, signal transduction, and bacterial pathogenesis.