The basic technique is simple and straight forward. Start by quilting the layers together, then slash all but the bottom layer with scissors and bloom the fabric by machine-washing and drying the stitched fabric. The resulting appearance will differ each time a layer is changed in order of placement or coloration. For best results, experiment with sample blocks until you create a combination you like. While my first vest was a bit time consuming the second vest was a snap.
Simple patterns work best.
If you'd like to start with a slightly less ambitious project, a vest is a great first project. Choose a loose fitting, dartless vest pattern. Small prints appear to be solid colours and large prints with dramatic colours are striking. You can use multiple layers of the same fabric, or combine different fabrics, depending on your test sample results. While rayon is a man-made fiber, it is created from cellulose and has many of the same properties as cotton.