Heavy chronic abuse may culminate in deafness, tremors, and dementia. Similar to toluene, but may also cause hallucinations. In addition to the hydrocarbons, toxicity by gasoline includes metals and other chemicals in the gasoline. Symptoms of gasoline abuse include insomnia, tremors, anorexia, and paralysis. First time users of these substances report the occurrence of panic attacks.
Tolerance usually develops rapidly to the desired effects of the substance.
Chronic use may also alter blood cells and suppress the immune system. Another aspect of the abuse of these substances is their purported ability to enhance sexual performance. One unique danger of inhaling nitrous oxide is when the substance in used directly from the storage tank. The gas is pressurised and often at a temperature much lower than room temperature. Inhalation directly from the take may fast-freeze tips of the nose, vocal cords, and lung tissue.