As the nucleus increase in size, the number of neutrons also increases because there are a greater number of protons to aid this process. If the size of nucleus increases excessively, the energy of the protons cannot be distributed evenly and therefore the nucleus will become unstable. Neutrons on the outer regions of the nucleus will become unstable a decay with the emission of an electron. The nucleus will increase its charge by one. The exact composition of space now becomes relevant to the study.
Space is a matterenergy field and therefore contains matter.
Since space is made up of matter, it must posses inertial properties associated with matter. The space between objects with no subatomic entities present possesses properties associated with inertial mass. Stepping back in history may shed light on the answer to this question. The people of the fifteenth century did not realize that the Earth was spherical because its curvature was small compared with their scope of vision. However, the shadow of the earth on the moon during a lunar eclipse gave an opportunity to view the spherical shape of the earth from a distance.