Drug-induced lupus may develop after taking certain prescription medications. Symptoms generally disappear after the drug is discontinued. Some people will have only a few symptoms, others may have them all. Discoid Lupus is confined to the skin, whereas systemic lupus may involve any organ system in the body, as well as the skin. However, this can't be predicted or prevented from happening.
Systemic lupus is irreversible, whereas drug-induced lupus generally is reversible.
There are other drugs which might possibly be associated with drug-induced lupus, but as yet there is no definite proof. Most of the drugs associated with drug-induced lupus can be safely used in people with SLE or discoid lupus if there are no suitable alternatives. Drug-induced lupus requires months to years of frequent use of a drug before symptoms appear. Usually symptoms disappear after six months after stopping the drug, but it could be days r weeks, it varies. The ANA may remain positive for years.