Dr. Thompson cited advanced molecular genetics techniques that can determine whether a tumor will become more aggressive. The amplification of a particular gene signals this. That gene can then be targeted with monoclonal antibodies, which will destroy only the cancer cells. Much genetic testing, however, occurs in the absence of disease. It may be done in an attempt to detect a familial predisposition for breast, ovarian or colon cancer.
Testing creates a new group of patients.
They're healthy, they don't have cancer, they may not ever get cancer, but they have a mutation that puts them at risk for getting cancer. The Cancer Genetics Screening Program began six months ago. Only a handful of patients have been tested so far, although the center has received many inquiries. This is mainly because initial counseling, which includes a close examination of the individual's family medical history, determines that either risks are lower than initially thought or the cancer in question does not have a genetic marker. A critical component of genetic counseling is presenting patients with the facts about testing, helping them decide if this is information they truly want, and what actions they will take once they have it.