Do not use occlusive dressings. Men with pregnant or possibly pregnant sexual partners must use condoms during sexual intercourse while taking bexarotene and for at least 1 mo after taking the last dose of the drug. Begin therapy on the second or third day of a normal menstrual period. Do not give more than a 1-mo supply of the drug at a time. Contraindicated in patients with known hypersensitivity to bexarotene or any component.
Urinary excretion is a minor excretory pathway for drug.
Pharmacokinetics my be altered. Increase in plasma bexarotene concentration may occur, but adverse effects are unlikely. The information provided above is based on the manufacturer's official US labeling for this product, dated July 2000. Inc. All rights reserved.