Krumm A, Hickey LB, Groudine M. Promoter-proximal pausing of RNA polymerase II defines a general rate limiting step after transcription initiation.
Transcriptional enhancers act in cis to suppress position effect variegation.
Proc Natl Acad Sci USA, in press. The immunoglobulin heavy chain LCR increases histone acetylation along linked c- myc genes. LCR is not necessary for an open chromatin structure or developmentally regulated transcription of the native mouse b -globin locus. Molecular Cell, in press. Bender M, Reik A, Close J, Telling A, Epner E, Fiering S, Hardison R, Groudine M. Description and targeted deletion of 5' HS 5 and 6 of the mouse b -globin locus control region.