A rare immunodeficiency disorder with recurrent bacterial and mycotic infections and impaired wound healing. Low serum levels of all classes of Immunoglobulins Lack of circulating B cells Lack of germinal centers and plasma cells in lymph nodes. Treatment of specific infections. Transient Hypogammaglobulinemia Of Infancy Ig synthesis particularly Ig G synthesis is delayed. Condition resolves on its own by 15 - 30 months of age.
Treatment involves administration of antibiotics or gamma - globulin or both.
Treatment of specific infections. Aggressive antibiotic therapy to control the infectious agent must be used. The basis of the developmental defect is not known. An association with maternal alcoholism is evident in some cases. Transplantation of a thymus from an aborted fetus can result in permanent reversal of the syndrome.