Vaccine development is one of the great successes of animal research. Because of animal research, only 1 in 10,000,000 vaccinations fail. In Canada and most other countries, the law requires that every batch of vaccines be tested for safety and efficacy. Animals such as dogs, cats and primates are used only for special or compelling reasons. Research with these animals is much more costly than research using fish or rodents.
Stringent regulations govern lab animal care.
In addition to humane considerations. Over 135 million people in the world suffer from diabetes. Half of these people would die an agonizing death if it were not for insulin. With insulin these people lead relatively normal lives. Insulin also benefits many dogs which suffer from diabetes.