An appropriate pause makes a joke . Timing is essential when dealing with people. You don't ask for a raise when business is not going well or when things are tense around the office. You don't try to correct someone who feels threatened by you. You don't ask for a favor when someone is under a lot of stress or angry.
Timing is important in cooking.
The juicy hamburger on the grill is raw meat if cooked for too little time and a clump of charcoal if it is cooked too long. Timing is important in medicine. If you catch a problem early you will be able to treat it more effectively. You timing is important in taking medication. If you take your medicine as directed it will be helpful.