The fewer things you have to keep track of and the easier it is for you to handle it, the less likely they will find you distracted. If you're traveling around, no one will know you wear the same clothes day after day. If you're not, then take clothes that mix and match so they look different. Comfortable, no-wrinkle, easy to wash out clothes are ideal. Misplaced luggage usually does arrive, but it might take a day or even two.
Some experienced travelers travel light enough that all of their luggage is carry-on.
Now you're on your way. Try not to look like a tourist , or at least not like a rich tourist. If you're with a group or at a conference, remove your name tag before going out on the street. Studying a map is a sign of a tourist. Try to do it in yourhotel room or at a restaurant table.