Six subjects continued on the ephedrine, caffeine and aspirin supplements, and after five months average weight loss in five of these six subjects was 11.44 pounds. The sixth subject experienced an astounding loss of 145 pounds after 13 months by self-imposed caloric restriction. In all studies, no significant changes in heart rate, blood pressure, blood glucose, insulin, and cholesterol levels were found. The doctors concluded that supplements containing ephedrine, caffeine and aspirin in these doses are well-tolerated in otherwise healthy obese subjects, and supports modest, sustained weight loss even without prescribed caloric restriction. Further, they conclude that the combination may be more effective in conjunction with restriction of food intake.
T here is also some indication that ephedrine can lessen the weight-gain symptoms of diabetes.
Mean weight loss in these diabetic patients was 16.3 pounds over the course of the treatment. Peripheral edema secondary to diabetic neuropathy is poorly understood and difficult to treat. It may have gone the way of most fads. But it appears that the concept of thermogenesis that stimulates energy expenditure within the body does, indeed, work, and safely with the proper supplements. Always, however, consult your physician, and observe the caveats at the right.