A Model for the Chromatin Fiber Dan Beard Department of Chemistry NYU Making effective use of the emerging flood of data on sequences and structures of biomolecules requires strategies for distilling detailed information into a minimal representation which captures the important features of a given system. This way, atomic-level details of a biomolecule are efficiently integrated into an accurate biophysical description of a system too large to treat on the atomic scale. Predicted small angle X-ray scattering profiles from oriented and solution samples and computed translational diffusion coefficients serve as criteria for judging the validity of our predicted structures.
Simulations reveal salt-dependent condensation analogous to the chromatin fiber.