Your doctor will inject solution. During the procedure, the doctor stretches your skin tight, inserts a very thin needle directly into the spidery blood vessel, and injects the special solution. There are many types of solutions your doctor may use. Often they include a high concentration of salt, which can scar the vessel and make it close up. You may feel a small needle prick and a slight burning sensation.
Some people also get muscle cramps.
Within seconds the doctor pulls the needle out and gently massages the area to spread the solution in the vein. Then the doctor tightly tapes a cotton ball over the injection site. One injection helps only about an inch of spider vein, so you'll probably receive multiple injections in a session. A session takes anywhere from 15 minutes to 45 minutes. Often, however, the vessels need to be treated more than once.