For you folks who are really opposed to medicating your pet, be assured that the medications are very helpful in providing the least amount of stress on your cat while it is going through an experience it finds horrific and unexplainable. Medication may be a very humane choice for your kitty. One of the most dangerous and embarrassing events you will encounter with your cat is trying to retrieve it from the rafters of the building you are in. And the odds are overwhelming stacked in favor of someone innocently opening the front door of the animal hospital just at the moment your kitty spies the tallest pine tree across the parking lot of the animal hospital. It can be dangerous, too, in the enclosed exam room when the veterinarian opens the crate or travel container.
Some cats are wound as tight as a miser just waiting for their chance to escape.
It may be best to open the crate or container and allow the cat to amble out on its own. A healthy cat may not move an inch for six to eight hours at a time. Allow a little food and water but don't expect the cat to even glance at the feast you've provided. At your motel sometime during the night, when everyone is sound asleep, the kitty will use the litter box and have a private banquet on its own terms. Your cat may use the litter box once, eat once e and drink once every twenty-four hours when on a long trip.