Early linear erosions are present in the oesophagus. In some cases, a proliferative and eczematous lesion of the skin may also develop. During the course of infection viraemia develops and may persist for up to two weeks. Virus persists in a variety of tissues for up to several weeks after experimental infection. There is extensive necrosis and ulceration of glossal epithelium.
Underlying tissue is reddened due to inflammatory hyperaemia.
From a 7 year old Pug bitch with uraemia. The specimen is one of serveral pieces of shining nodular gum tissue removed from the lingual and labial side of the upper carnassial teeth of a 9-years old Labrador dog. Lesions of this kind are common in the older dog. They are covered by stretched gingival epithelium and consist predominantly of dense fibrous connective tissue. They are essentially benign nodules but may be removed surgically because the larger examples cause a degree of oral discomfort.