Essential fatty acids must be taken in the diet as the body can not make them. No reports of toxicity, when used at recommended doses. Mixed tocopherols contain d-alpha, beta, delta and gamma tocopherols. Mixed tocopherols offer the greatest benefit. Look for natural mixed tocopherols.
Vitamin E is an antioxidant.
There were studies done in the late 1940's showing it to relieve hot flashes and postmenopausal vaginal dryness. More recent studies are lacking. There are other benefits. Vitamin E is also being studied for its effect on Alzheimer's disease and cancer. Combining vitamin E with other anti oxidants such as selenium, chromium, beta-carotene, and vitamin C may offer a synergistic effect.