Uncommon allergic reactions can occur, otherwise no significant side effects or interactions have been observed. Quercetin serves as the backbone for other flavonoids, and is the most active of the flavonoids. Many medicinal plants have a significant quercetin content. Although human studies are limited, its physiological actions explain its use in inflammatory and allergic conditions including asthma, hay fever, rheumatoid arthritis, lupus, diabetes and cancer. Sorbitol is implicated in the development of diabetic complications including cataracts, neuropathy and retinopathy.
Studies show decreased cataract formation in the lens of diabetic animals.
Its potential influence on diabetes may also relate to enhanced insulin secretion, protection of pancreatic beta cells from free-radical damage, and inhibition of platelet aggregation. Quercitin has anti-viral action against a number of different viruses, and inhibits a number of different cancers in experimental models. Inhibition of human lens aldose reductase by flavonoids, sulindac and indomethacin. Experimental studies suggest potential benefit in arteriosclerosis, heart disease and stroke. No side effects or significant drug interactions have been reported.