This volume examines the evidence for genetic contributions. There is discussion of the data and methodological problems of disentangling genetic and environmental sources. In animals, aggression is commonly an appropriate response to environmental stimuli, and data from animal studies of the inheritance of aggressiveness are included. A heritable tendency to behave in a particular way would have significant implications for criminology. Important issues also arise from moral philosophy.
Separate chapters examine evolutionary and anthropological aspects of violence and warfare.
Considers the molecular mechanisms of gene mutation and evolution Gene mapping is proceeding rapidly, especially with the continuation of the human genome project. At the moment, however, little consideration is being given to the variation present in different human populations. This book discusses methods of analysing population genetic data and how contemporary genetic heterogeneity arises during the migration and evolution of human populations. Many different pathological conditions are currently under investigation as therapeutic targets of purines, including cardiovascular conditions, behavioural disorders, inflammation, immunoregulation and neuroendocrine function, and cancer. This book draws together research on all aspects of P2 purinoceptors and discusses their use in different therapeutic areas.