It makes antibodies against it and can severely damage or even destroy the organ. Diseases such as lupus, hypothyroidism, rheumatoid arthritis and the type of diabetes that requires insulin, are examples. The stomach lining also may be attacked by the immune system leading to loss of the stomach cells. This causes acute and chronic inflammation which can result in a condition called pernicious anemia. The anemia occurs because the body no longer can absorb vitamin B12 due to a lack of a key stomach factor, destroyed by the chronic inflammation.
Stomach cancer can even occur later in life.
Along with aspirin, they reduce a protective substance in the stomach called prostaglandin. These drugs usually cause no problems when taken for the short-term. However, regular use can lead to a gastritis as well as a more serious ulcer condition. Alcohol Alcohol and certain other chemicals can cause inflammation and injury to the stomach. This is strictly dose related in that a lot of alcohol is usually needed to cause gastritis.