The paradigm that follows shows systematic analysis of metabolic pathways from the properties of individual reactions. After reviewing enzyme kinetics and regulation, methods for analyzing the behavior of simple enzymatic sequences will be presented. Particular emphasis will be placed on issues of kinetics and thermodynamics of multi-reaction systems. Lectures on the role of experimental tools such as DNA micro arrays and protein profiling techniques will be presented in the context of Metabolic Engineering. Tools for data visualization and data mining will also be presented.
Time is provided for group interaction among faculty and attendees.
Course participants will be provided with detailed course notes and a copy of the recently published book Metabolic Engineering .