Tetrad analysis allows direct analysis of the products of meiosis in one cell. Mutants can be isolated in haploids or diploids. Recessive mutations are immediately recognized in haploids. If mutations are being sought in an essential process, mutagenesis can be done in diploids. The recessive mutation is identified in the haploid cells after sporulation.
Yeast cells are easy to transform.
Several plasmid vectors have been developed that allow easy growth in either yeast or bacteria. Artificial linear chromosomes allow the study of chromosome structure. Yeast chromosomes can be separated by size using pulse-field gel electrophoresis. The McGraw-Hill Companies. Any use is subject to the Terms of Use and Privacy Policy .