The signs and symptoms of this form of the disease vary greatly from one person to another. The most common symptom is an enlarged spleen, which is generally painless. Other symptoms may include an enlarged liver, frequent nosebleeds, bruising, bone pain, and a lack of energy. Some people may experience only a few of these symptoms, while others may have many. One person may have bone problems, while another may have only an enlarged spleen.
Symptoms can be present in any combination.
In addition, children with Type I Gaucher disease may be shorter than their peers and have delayed puberty. Type II is much less common than type I. Symptoms usually appear in an infant several months after birth. The disease affects the infant's nervous system, resulting in an inability to support the head and difficulty breathing. Infants with this type of disease usually die by the time they are 2 years old. This form of the disease affects the person's central nervous system.