Be sure to check the instructions carefully. Do not take azithromycin at the same time as antacids that contain aluminum or magnesium. They will reduce the amount of azithromycin in your blood. The side effects of azithromycin mostly affect the digestive system. They include diarrhea, nausea, and pain in the abdomen.
Some people get very sensitive to sunlight.
Others may get headaches, be dizzy or sleepy, or have some problems hearing. Very few people who take azithromycin get these side effects. However, most anti-HIV medications also cause problems in the digestive system. Azithromycin could make those problems worse. Antibiotics kill some helpful bacteria that normally live in the digestive system.