Don't ask your viewers to take a circuitous route to find information. If you have a lot of information on the site provide a search function or, at a minimum, a content listing so that viewers can quickly find what they are looking for. Don't create gratuitous animations, blinking or scrolling text just to prove that you can. These are best used to highlight some feature or information to which you want to call attention. Use contrasting colors judiciously.
Some combinations are very hard on the eyes.
Make contact information readily available. List your name and phone number in an obvious location or add an email link. It is also a good idea to put your URL on the site. Make sure you test your site in print. Some of your viewers will want to print your information to circulate to colleagues or to keep for later review.