Cisplatin is a chemotherapy drug used to treat some forms of cancer. Preliminary evidence has shown that glutathione injections may protect nerve tissue during cisplatin therapy without reducing cisplatin's anti-tumor activity. There is no evidence that glutathione taken by mouth has the same benefits. Magnesium and Potassium Cisplatin may cause excessive loss of magnesium and potassium in the urine. Two case reports and one review article suggest that both potassium and magnesium supplementation may be necessary to increase low potassium levels.
Some doctors suggest monitoring the level of magnesium in red blood cells rather than in serum.
They believe the red blood cell test may be more sensitive in diagnosing magnesium deficiency. The level of selenium used in this study is potentially toxic and should only be used under the supervision of a doctor. Sodium Cisplatin may cause depletion of sodium due to kidney damage. Threlkeld DS, ed. In Facts and Comparisons Drug Information.