The investigations are based on diffraction experiments with conventional X-radiation and with synchrotron and neutron radiation supplied by large national or international research laboratories.
Special interest is directed to diffraction experiments at low and ultra low temperatures.
In collaboration with drug developing groups in university or industry labs the implications of electronic properties derived from experimental charge density work to molecular design techniques are investigated. Compounds of current interest are new generation oral antidiabetics, antithrombotics and beta-lactam antibiotics. In collaboration with a number of research group in East Asia, we are working on the isolation and structural characterization of active compounds from domestic plants playing a role in traditional Asiatic medicine.