Ash DV TI - Erythroplasia of Queyrat treated by topical aminolaevulinic acid photodynamic therapy.
Treatment is often difficult and is associated with significant recurrence rates.
It has been used successfully to treat benign, premalignant and malignant skin diseases. Two further patients with more extensive disease achieved a significant improvement, allowing easier treatment by laser vaporization. Although topical ALA PDT offers the advantages of tumour specificity, preservation of function and a good cosmetic result, more extensive EQ appears less responsive to this new therapeutic modality using current treatment parameters. To explore the possibility of reducing the margin of clearance at surgery for carcinoma of the penis without causing an increase in the incidence of local tumour recurrence, so that the functional and cosmetic compromise associated with penectomy might be minimized. Sixty-four patients underwent partial or total penectomy based on the extent of tumour.