Hyper IgM is a rare, genetic combined immunodeficiency that usually becomes apparent in the first or second year of life. People with Hyper IgM are susceptible recurrent bacterial and opportunistic infections.
Treatment is with high doses of immunoglobulin and the aggressive management of infections.
Some Physicians recommend Bone Marrow Transplantation. The Hyper IgM listserv is an email discussion forum, for people with Hyper IgM and their families, as well as doctors, nurses and reserchers interested in the condition. The listserv aims to promote the exchange of experiences and knowledge about the condition.