The Number of Active Brain Lesions Brain lesion load can be measured in a crude fashion by grading the size of the lesion by their largest diameter. Lesion area can be measured more precisely by outlining them manually on a computerized image. More fully automated lesion area measurement techniques, such as Thresholding and Edge Detection have been developed. The accuracy of Lesion Load Measurement will also be increased by thinner slices, which reduce partial volume errors. MRI monitoring helps make this distinction.
Sequences are the current method of choice.
Minimizing scan time is important for both reducing cost and improving patient comfort. The appearances of SE and FSE sequences are very similar, and they are equally sensitive in detecting MS Lesions. Other MR techniques are needed that specifically identify the pathological features most likely to result in disability, namely DeMyelination and Axonal Loss. MR Spectroscopy are two techniques that show promise in this regard. The macromolecular structure of Myelin is the physical basis of MT, by using off-resonance irradiation, macromolecular protons can be saturated.