It contributes to the seminal fluid a secretion containing acid phosphatase, citric acid, and proteolytic enzymes, which account for the liquefaction of the coagulated semen. The rate of secretion increases greatly during sexual stimulation. Because of its position around the urethra, enlargement of the prostate quickly interferes with the normal passage of urine from the bladder.
Urination becomes increasingly difficult, and the bladder never feels completely emptied.
If left untreated, continued enlargement of the prostate eventually obstructs the bladder completely, and emergency measures become necessary to empty the bladder. If the prostate is markedly enlarged, chronic constipation may result. The usual remedy is prostatectomy. In men over 60 years of age, cancer of the prostate may occur. Prostatitis is a relatively common inflammation of the prostate and may be acute or chronic.