Coming from a Central or South American country it is necessary to use one of national airlines. Quito Quito , population 1.2 million, is situated on the Andean altiplano at an altitude of 2850 meters. It is only 22kms south of the equator but enjoys a temperate climate. It is a great place for tourists and backpackers, with heaps to see and very economical. Quito is one of my favorite South American cities.
Tour agencies are everywhere.
The country is safe for DIY travellers. Cuenca is about 300kms south of Quito. It is Ecuador's third largest city and the most beautiful. The city center is a delight with Spanish colonial buildings and cobblestone streets. Accommodation I stayed in two places that I fully recommend.