The successes of science are renowned and scarcely a week goes by without some new and important progress. The attraction of the scientific method goes beyond its tremendous power and scope to its uncompromising honesty. Every new discovery or theory is required to pass rigorous tests of approval by the scientific community before it is accepted. Of course in practice, scientists don't always follow textbook strategies. However, these are aberrations, generally science leads us to reliable knowledge.
Some scientists believe that science can explain everything, at least in principle.
It means that however successful our scientific explanations may be, they always have at least one unprovable assumption built-in. For example, a Physics explanation of some phenomenon assumes that the laws of physics are valid everywhere at once, absolutely, for all of time, and without anything escaping them. This is clearly unprovable. Because every explanation system has at least one unprovable assumption built-in, we have to accept something as a foundation on the basis of belief. Origins and goal of Physics 2500 years ago in ancient Greece, the first systematic attempt was made to establish some common rational grounds for understanding the nature of things.