Cycle helmets appear to be effective. However, programmes which do not take financial considerations into account may have lesser impact. Car restraints work. There has been no evaluation of the impact of the 1989 legislation in Britain which made rear restraints for children under 14 compulsory. In the home environment interventions with safety devices, product design and education have met with some response.
Social factors play a significant role.
Community wide interventions have been evaluated, but are not reported as the research design is rejected by the reviewers. Report 49 concerns Ceredase in the treatment of Type 1 Gaucher's disease . Ceredase is beneficial but high cost treatment. Report 50 concerns cognitive behavioural therapy in the treatment of chronic fatigue syndrome . Recommended as an outpatient treatment for certain patients, but not as an inpatient treatment.