Postmortem examination was not permitted by the family. The findings in this newborn are compatible with the diagnosis of cryptophthalmos syndrome according to the diagnostic criteria proposed by Thomas et al. The diagnosis is suggested if the patient has at least two major criteria and one minor criterion, or one major criterion and four minor criteria. The major criteria are cryptoph- Figure 1. Complete cryptophthalmos in the right side, partial cryptophthalmos in the left eye and the broad and depressed nasal bridge.
Soft tissue syndactyly of all fingers.
In this report, the baby had all the major criteria, in addition to congenital malformation of the nose, larynx, and unilateral renal agenesis as minor criteria. The baby was diagnosed to have total anomalous pulmonary venous return, which was a new finding in this syndrome. The pericardial effusion could be part of the hydrops fetalis. The exact mechanism of the association of cardiac anomalies and Fraser syndrome is not understood. However, there was an association between airway abnormalities, in our case a laryngeal stenosis, and pulmonary vessel abnormalities, despite the difference in their early development.