Blood Pressure and fluid regulation in heart transplant recipients. Mechanisms of steroid induced osteoporosis and skeletal muscle myopathy in solid organ transplantation recipients. Mechanisms of exercise intolerance in heart failure. Effects of cocaine in perinatal physiology, especially its effects on fetal brain metabolism and function. Also interested in prenatal and perinatal brain injury due to asphyxia.
Research program is active in both clinical and basic science areas.
Has a strong emphasis on the importance of vascular fluid volume on cardiac and renal function. Sports medicine programs seek ways to facilitate training and improve performance. Active in the mechanisms involved in producing cold hypertension. Pathophysiology of ischemic heart disease, and ventricular function coronary blood flow in relation to coronary stenosis, coronary artery spasm and unstable angina. Host tumor nutrient interaction in order to define a nutritional formula supportive of host growth while impeding tumor growth and development.