You must rediscover yourself and define a new context in which to place your idea of what it is to exist. This process is lifelong. You must wake everyday and look at yourself and the world anew. Now, this isn't to say you never decide upon certain beliefs. It doesn't mean you have to relearn how to drink out of a straw every time you get a Coke at McDonalds.
Simple assumptions come easy.
Rather, in a practical sense you make you're best guesses about the questions you ask yourself and go on about your daily routine. At the same time you remember that all you believe is conjecture. You keep yourself on the lookout for different ways to view each and everything you believe. You try on different beliefs to see how they work and what uses they might have. You remember all concepts are tools and you remind yourself not to hang on too tightly to one idea or another.