This affects the transmission of pain signals to the brain. Neuropathy can be a minor nuisance or a disabling weakness. It usually shows up as a feeling of pins and needles, burning, stiffness, or numbness in the feet and toes. It can also be tickling sensations, pain when there's no reason for it, or sensations that seem more intense than normal.
Serious neuropathy can cause difficulty walking or standing.
But special tests may be needed to find out what is causing neuropathy. These tests measure the tiny electrical currents in nerves and muscles. With some types of neuropathy, the amount of electric signals is reduced. With others, the speed of the signals drops. The first response is to discontinue any drugs that are known to cause neuropathy.