A very complex series of reactions activate the clotting process. However, in CFS, FMS, MPS and other chronic conditions, continuous generation of low levels of thrombin can occur. Genetic coagulation defects can lead to hypercoagulation. Chemical exposure can result in changes that trigger the coagulation process. The fibrin coating the capillaries and producing thick blood can make viruses and bacteria less accessible to treatment.
Thicker blood is harder to pump.
By depriving the gut of proper nourishment, hypercoagulation may be a major factor in Irritable Bowel Disease. If the bowel is deprived of blood, it will sluff off its contents. The endothelial cells lining the capillaries are the source of heparans, the body's natural blood thinners. When fibrin coats these cells, the heparans cannot be released, reducing the body's ability to dissolve the fibrin. Five substances are measured, and abnormal results on any two are considered a positive test result.