Two of the most important are food and asthma. The severity of an allergy often depends on the individual's immune system tolerance. In the case of food allergies, symptoms range from a minor upset stomach to sometimes death. Many types of foods can cause allergies such as milk, soy, onions,walnuts, shellfish, wheat, and even chocolate. Proteins in food are responsible for allergies.
Proteins are ubiquitous and show diverse shapes, sizes, and functions.
One of the most common types of protein allergens are those found to have intrachain disulfide bonds. The protein allergens will become less immunologically active and more digestible. Results have been obtained with a dog model using wheat flour and milk as a source of allergens. My project this summer was to compare the allergenicity of the major groups of wheat proteins between sensitized dogs and human patients having natural allergies. The wheat flour proteins can be separated based on their solubility.