One of the simplest methods of determining this is still the most effective. Sit down with a pad of paper and draw a line down the middle. Consider not only salary and benefits, but the attractiveness of the position to you, the company, and your potential supervisor and coworkers. Consider the relative importance of each item. First, you have to determine the most important considerations for you.
Most employers still prefer a mailed resume on good quality resume paper to e-mailed resumes.
You should always research an organization before applying for a position. You should not discuss salary until the employer has extended an offer to you. An interview should be followed up with a thank you note within no more than 24 hours after the interview.