You have determined that the first step is either activation of a G protein coupled receptor or a receptor tyrosine kinase. Outline the signal transduction pathway that leads to LTP in the hippocampus. What would happen if nitric oxide synthase was defective. Outline a signal transduction pathway by which activation of a GPCR leads to both the opening of an ion channel and an increase in the total number of ion channels 9. Outline a signal transduction pathway by which activation of receptor tyrosine kinase leads to both changes in the cytoskeleton and changes in gene expression.
Nitric oxide plays an important role in the regulation of blood pressure.
Outline the signal transduction pathway that mediates this interaction. If you wanted to treat high blood pressure by making this interaction more effective, what molecules would you target with drugs. You are studying the effects of potential anti-cancer drugs on the actin cytoskeleton of cells in culture. You notice that factor X causes the actin fibers to completely depolymerize. Factor Y causes large crosslinked networks of fibers to form .