Design Prospective multicenter cohort study. Setting Fifty-two clinical centers in 17 European countries included in the EuroSIDA Study Group, from August 1996 to April 1999. All analyses were intention to treat.
Older patients are more likely to achieve virological success.
Thereafter, the higher durability of virological response is predicted by an antiretroviral-naive status and by the use of specific regimens. Lower baseline HIV-1 RNA levels and rapid maximal viral suppression seem to be other important factors in the durability of virological response. Arch Intern Med. Hospital Universitari Germans Trias i Pujol, Crta. Accepted for publication October 20, 1999.