The general objective of the current project is to develop new effective and selective cancer therapeutics. Problem to overcome Cancer is the second most common cause of death in the developed world causing enormous human suffering and significant economic losses and strains both by losses of workforce and the significant resources that are spent on the care of terminally ill cancer patients. The advances of conventional medicine using aggressive combination therapies have significantly improved the survival rates among cancer patients in recent decades. However, at the present time the limits of usefulness are being approached for conventional therapies and further advances will require principally new approaches.
Skin cancer is the most common type of cancer in the Western world.
It can be divided into melanoma and nonmelanoma skin cancer. Consequently there is an increasing demand for methods for efficient treatment of skin cancer. The advances in genetics and molecular biology have made available a large body of new information on the molecular mechanisms governing tumor formation and malignant progression. Our research group has been working on uncovering molecules important for both skin cancer formation and progression. Gene therapy affects in most cases too few cells to be useful.