They will not achieve the quantity of the large corporations, however, they will have higher quality. Computer chips could be assembled quickly with special equipment in a garage Every surface would be painted over to control dust, plastic would be hung over the walls. An airlock and a ventilator and filter will keep the air clean. Ask yourself how this will affect society. Consider carefully the affects of super weapons such as nuclear bombs.
Proliferation is unstoppable.
It may serve to stabilize governments, however, it also might serve to increase violence, especially if there are less consequences than the nuke. Pollution will affect the world. Radioactive waste has to be held safe for the rest of eternity. Many industrial chemicals are toxic and carcinogenic. Today, the government requires them to be stored safely, however if government falls, there is nothing to prevent the corporations from dumping them, preferably on other people's land.