Canes of the current season's growth are bent down and covered with earth, the tips being left uncovered. By fall the cane will be developed roots and is severed from the parent. Seedling plants can also be grafted to desirable cultivars. Bench grafting is the method commonly used. Muscadine rootstock is not suitable for American and European grapes because of compatibility problems.
Muscadine grapes are much less bothered by diseases than American and European grapes.
They are essentially immune to phylloxera, nematodes and Pierce's disease. In the West only mildew is likely to be a problem. Leaf hoppers, aphids and flea beetles are occasional insect pests. As with all grapes, birds can also be a problem. The fruit also tends to fall when ripe.