Margin in skin cancer surgery, the amount of normal-appearing tissue removed around the tumor. Margin is usually measured in centimeters. The main goal is complete removal of the melanoma. See Thickness for a discussion of the relationship between tumor thickness and 5-year survival after treatment. Melanocytes cells that make the skin pigment melanin .
Melanin is made in small granules, called melanosomes, within the melanocyte.
Melanoma - a tumor that arises in melanocytes . This tumor is biologically very aggressive. It usually appears as a pink or red nodule. This lesion may also be mistaken for a cyst. It may be pigmented or non-pigmented.