In addition we have identified polar amino acids important in activity of the mammalian protein. We also have a great interest in pH regulation and ion movements in yeast. This protein functions in osmotolerance in yeast and plants. We have examined amino acids important in cation binding and transport in this protein. Our long-term goal is to understand how ions and coordinated and transported in membrane proteins.
Many new projects are underway.
We are always interested in recruiting high quality personnel so please contact me if you are interested in this area. For more information on Dr. Fliegel's research, also see the Community of Science database. Identification and localization of the sod2 gene product in fission yeast. Role of a Poly T rich region in Regulation of Expression of the NHE1 Promoter.