Before or after opening, Karo syrup may be stored at room temperature.
Storage conditions affect product quality.
Light corn syrup may turn slightly yellow with age, but this is normal and not harmful. Karo syrup is safe to eat for an indefinite period of time whether it has been opened or not opened. Bottles may be refrigerated after opening, however, the syrup will be thicker and slower to pour. Corn syrup serves different functions in different types of recipes and in products you purchase. It controls sugar crystallization in candy, prevents the formation of ice crystals in frozen desserts, enhances fresh fruit flavor in jams and preserves, sweetens and thickens relishes.