Histologically, it resembles plexiform vascular network, a mixture of stellate and spindle-shaped mesenchymal, and lipoblasts. The CT images demonstrate a relatively homogeneous or cyst-like mass with relatively sparse fat attenuation. Round cell and pleomorphic types are poorly differentiated tumors of high-grade sarcoma. Histologically, round cell has sheets of round cells and lipoblasts. They often do not contain fat.
Pleomorphic form has large lipoblastic multinucleated cells.
The CT and MR imaging characteristics are difficult to distinguish from each other, but they usually appear as heterogeneous and lack the fat component which is common to well-differentiated and myxoid types. Liposarcoma may present with mixed histologic types within in the same lesion. Characterizing the various types determine the prognosis and surgical planning. On a high-grade tumor such as round or pleomorphic types, amputation or chemotherapy is preferred therapy. Two distinct masses with heterogenous soft tissue and fatty attenutations.