Do not use with Seldane, Hismanal, Propulsid, Halcion, Versed, Cordarone, ergot derivatives, quinidine or rifampin. When taken along with rifabutin, its dose will need to be adjusted by half. Viracept also decreases the blood levels of hormonal contraception so it may decrease the effectiveness of some oral contraceptives or DepoProvera. The most common side effects are nausea, diarrhea, stomach discomfort, liver toxicity, diabetes, and an increase in cholesterol. Drink at least 1.5 quarts of water daily to reduce the chances of kidney stones.
Some folks also experience nausea, abdominal discomfort, and bloating.
Increased bilirubin occurs but only infrequently as a result of decreased liver function. Rarely, rapid breakdown of red blood cells can occur and some with hemophilia have increased bleeding. Nausea, diarrhea and vomiting. Monitor liver enzymes. Risk of liver problems increases with preexisting liver disease.