P. A common promoter variant of the leptin gene is associated with changes in the relationship between serum leptin and fat mass in obese girls. Genetic obesity unmasks nonlinear interactions between murine type 2 diabetes susceptibility loci. The subcutaneous lipolytic response to regional neural stimulation is reduced in obese women. Impaired capacity to lose visceral adipose tissue during weight reduction in obese postmenopausal women with the Trp64Arg beta3- adrenoceptor gene variant. Effect of dietary energy restriction on glucose production and substrate utilization in type 2 diabetes.
Obesity induced by a high-fat diet is associated with reduced brain insulin transport in dogs.
Plasminogen activator inhibitor 1, transforming growth factor-beta1, and BMI are closely associated in human adipose tissue during morbid obesity. Involvement of protein kinase C in human skeletal muscle insulin resistance and obesity. Obesity is associated with a decreased leptin transport across the blood-brain barrier in rats. Divergent regulation of Akt1 and Akt2 isoforms in insulin target tissues of obese Zucker rats. Differential brain responses to satiation in obese and lean men.