If you're 200 percent of your ideal body weight, your risk is probably six to eight times higher than normal. Second, that fat is in an area drained by a major vein that picks up the fat's metabolic by-products and takes them to the liver. But the liver doesn't know the message is false, so it responds by churning out an emergency ration of glucose into the bloodstream. More glucose in the blood makes the pancreas dump in more insulin. More insulin causes the liver to generate more glucose.
More glucose makes the pancreas dump more insulin.
Eventually the whole system breaks down, says Dr. Kohrt. Your body will either shut down insulin production or the muscles and organs will refuse to accept it. Either way, you've got diabetes. When Pregnancy's the Problem Pregnancy is a time of great adjustment for a woman and her body. But these same hormones can bring on diabetes in a woman who has never before been diabetic.