This guideline is an update of the 1979 Canadian Task Force recommendations on blood group incompatibility in pregnancy. This phenomenon is not dangerous to the fetus unless there is an incompatibility between the mother and her fetus with respect to the D antigen of the red blood cells. Once isoimmunization has occurred, the severity of fetal hemolysis varies.
Options Screening for D blood type is done using hemagglutination.
C Poor evidence regarding inclusion or exclusion of the condition in a PHE, but recommendations may be made on other grounds. Evidence from well-designed controlled trials without randomization. Evidence from comparisons between times or places with or without the intervention. Dramatic results in uncontrolled experiments could also be included here. III Opinions of respected authorities, based on clinical experience, descriptive studies or reports of expert committees.