Methanol is used as an extractant in chemical processes and as a denaturant in ethanol. In the industrial setting, therefore, inhalation of methanol fumes is a risk. In addition, there have been reports of poisoning in beverages resulting in large outbreaks. Alcoholics commonly consume methanol as a substitute for ethanol. The excessive consumption of methanol then leads to intoxication.
Suicide attempts using methanol are uncommon.
Any cause of altered mental status with acidosis and potential cardiovascular collapse. Renal profile Significant methanol ingestion leads to metabolic acidosis, which is manifest by a low serum bicarbonate level. An increased anion gap is seen secondary to high lactate and ketone levels. This is probably due to formic acid accumulation. Serum osmolality Methanol results in an elevated osmolar gap.