Please note the brand names, Deconsal II Tablets and Deconsal L.A. Tablets have been used in this monograph where noted to avoid confusion. Each scored, light blue Deconsal L.A. Tablet provides 120 mg pseudoephedrine hydrochloride and 400 mg guaifenesin in a sustained-release formulation intended for oral administration.
Pseudoephedrine hydrochloride is a nasal decongestant.
Guaifenesin is an expectorant. It does this by vasoconstriction which results in reduction of tissue hyperemia, edema, nasal congestion, and an increase in nasal airway patency. The vasoconstriction action of pseudoephedrine is similar to that of ephedrine. In the usual dose it has minimal vasopressor effects. Pseudoephedrine is rapidly and almost completely absorbed from the gastrointestinal tract.