The moderate-fat reduction diet is optimal for ensuring adequate nutritional intake. These diets are high in saturated fat and cholesterol. Metabolic Parameters Low-CHO diets result in ketosis, and may cause a significant increase in blood uric acid concentrations. However, the macronutrient and fatty acid composition of energy-restricted diets can exert substantial effects on blood lipids. There are significantly greater decreases in LDL cholesterol during active weight loss when diets are low in saturated fatty acids.
Many factors influence hunger, appetite, and subsequent food intake.
Macronutrient content of the diet is one, and it may not be the most important. However long-term body weight regulation appears to be controlled by hormonal signals from the endocrine pancreas and adipose tissue, i.e., insulin and leptin. All fat-restricted diets provide a high degree of satiety. These diets, high in fiber and water content are low in caloric density . However, it is not clear that restricting fat provides any advantage over restricting carbohydrates.