The nearly 1,000,000 ampules of living cells stored in liquid nitrogen there include samples of every known type of xeroderma pigmentosum, a disease that sometimes renders patients' DNA repair machinery defective. For stories on how researchers around the world have used those samples to develop more sophisticated models of DNA repair, please see pages 14-15.
Ongoing studies explore how ribonucleases can best be used to treat cancer.
A DNA repair model in development now involves genetics, structural biology, and signal transduction. The Coriell Institute for Medical Research in Camden, N.J., houses the largest collection of living cells in the world. Beckman's Coulter's Microfuge 18 combines user-friendly features in a compact instrument. Surveys of manufacturers and distributors for current prices and specials. Chemiluminescent detection systems for reporter gene assays.