DFMO is known to work by inhibiting or stopping an enzyme that helps tumors grow.
Patients have an equal chance of receiving either one.
All patients who enroll in this study will need to take their study medication, by mouth, once a day for 1 year. Blood will be drawn to monitor patients' blood counts. Potential side effects include nausea and vomiting, loss of appetite, diarrhea, abdominal pain, ringing in the ears, headaches, or generally not feeling well. DFMO may cause some blood cell counts to be lowered. At doses 15-100 times higher than the dose used in this study, a slight reduction in hearing frequency was noted.