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Rabies primarily attacks the nervous system and causes an encephalitis.
The virus is transmitted in saliva from the bite of an infected animal. The virus will begin shedding in saliva a short time before clinical signs develop, usually less than 10 days. For both humans and domestic animals, the primary source of rabies is the bite of a rabid wild animal. The most common of these are skunk, raccoon, bat, and fox. Currently, the number of cats infected with rabies has surpassed that of dogs.