The 18q- syndrome is a genetic disorder characterized by deletion of a portion of the q arm of chromosome 18.
Most deletions are terminal, vary in extent, and remove a gene for myelin basic protein.
This is likely the cause of a common symptom reported in 18q- children, dysmyelination. All images were corrected for differences in system sensitivity resulting from different bandwidths per pixel. All images were axial sections with slice thickness of 5 mm and 1-mm gap. Flow compensation was used in the dual-echo sequence. All images were acquired on a 1.9 Tesla Elscint Prestige human clinical MR imaging system.