Our work provides insight into these diseases. Our recent work has been on the oxygenation of the cat retina, a good model for the human retina in many respects. We use oxygen-sensitive microelectrodes that measure oxygen levels with excellent spatial resolution. Simultaneously we measure local neural activity to provide an index of retinal function. The focus of our current work is to understand the relationships between oxidative and glycolytic metabolism in the retina, and to work on animal model for diseases such as retinal vascular occlusion, diabetic retinopathy, and photoreceptor degenerations.
Perfluorocarbon emulsion improves oxygenation of the cat primary visual cortex.
J. Applied Physiol. Oxygenation of the cat primary visual cortex. J. Applied Physiol. Retinal hypoxia in long term diabetic cats. Effects of adaptation level and hypoglycemia on function of the cat retina during hypoxemia.