Profit will be possible wherever revenues exceed costs. Revenues, of course, vary from place to place, as do costs. Somewhere there is a location where the difference between revenues and costs will be at a maximum, and that may be the optimal location for a given business. The spatial range of profitability is very narrow for some types of business. Some need to be near their source of materials.
Mushroom caning, copper smelting, and a sawmill are examples.
The manufacture of mobile homes, newspaper printing, a gourmet restaurant and most forms of retailing come to mind. Other businesses, especially services that deal with information which can be transported via new communication technologies to almost any place in the world, have a large spatial range of profitability. Examples may include business consulting, investment management, and certain types of computer programming.