Research Overview Discovery and translational research are core values of the Department of Medicine. The Department has experienced substantial growth in research activities over the last 15 years and currently is ranked 16 th among departments of medicine in terms of funding from the National Institutes of Health. The breadth of this research activity is exceptional, ranging from medical informatics and health services research, through a very active clinical trials program, including one of three NIH sponsored Vector Laboratories for preparation of clinical-grade retroviruses, to basic cellular and molecular biology and genetics. Nationally recognized programs in pancreato-biliary diseases and cholangiocyte biology, and a very large group of investigators participating in an Alcohol Research Center. Recent award of a comprehensive Cancer Center.
Plans are underway for expanding programs in breast, prostate and lymphoma research.
Establishment of an advanced technology imaging center for the study of epithelial tissues within the Division of Nephrology and their Program Project on Cytoskeletan abnormalities in Renal Ischemas. Well-funded programs on the interactions of pathogens with the alveolar cells and the immunology of lung transplantation. Direction of a national trial of doxycycline in the treatment of osteoarthritis, and the application of an animal model of osteoarthritis. An established division of Clinical Pharmacology involved in studies on drug disposition in the elderly, drug interactions at the level of cytochrome P450s, and the use of chiral drugs. An Aging Center within the Division of General Internal Medicine coordinating aging research activities across the campus.