In symptomatic patients surgical excision, curettage, cryotherapy, or cautery may be used to ablate the lesions. A severe anterior uveitis has been described secondary to rifabutin therapy. This responds to topical cycloplegics and topical steroids. A non-specific uveitis associated with HIV infection and possibly responsive to AZT has been described. Neurological evaluation, neuroimaging studies, and further evaluation by appropriate specialists are recommended in cases of orbital and CNS opportunistic infections and malignancies.
Orbital lymphoma can produce proptosis and visual loss through a mass effect.
When the tumor is more indolent, pain and diplopia may be the first signs of lymphoma. CNS lymphoma, depending on its location, may produce visual field abnormalities, ocular motility disturbances, or uveitis. B. Orbital aspergillosis Orbital infection with Aspergillus organisms can produce proptosis and may involve the adjacent sinuses. D. Central nervous system toxoplasmosis Central nervous system toxoplasmosis, depending on its location, may produce visual field abnormalities or ocular motility disturbances. E. Cryptococcal meningitis Cryptococcal meningitis can cause papilledema.