Hemorrhage and inflammation are rarely seen. The optimal treatment has not been established and prognosis is poor even with high doses of combinations of ganciclovir, foscarnet, both intravenously and intravitreally, and acyclovir. Patients often develop retinal detachments. Ocular toxoplasmosis Ocular toxoplasmosis may present with single or multiple lesions white to cream in color. There may be significant vitritis, which can partially obscure the view of the fundus.
Retinal hemorrhage is rare.
In contrast to ocular toxoplasmosis in immunocompetent individuals, AIDS patients do not usually have pigmented lesions suggestive of prior retinal infection. Central nervous system evaluation for toxoplasmosis is recommended in patients with ocular toxoplasmosis. Therapy for ocular toxoplasmosis should be the current regimen for systemic toxoplasmosis. Atovaquone can be considered for patients who fail standard therapy. Maintenance treatment should be continued or lesions will relapse.