More studies need to be conducted in order to understand more fully how genes come into play in determining smoking behavior and its link to depression. Nicotine has been implicated as the primary culprit in the physical dependence on cigarettes. Currently under investigation is whether smokers use this potent drug to self-medicate their depression. The Artificial Passion discusses the unique appeal of nicotine. Mr. Krogh states that the average person might find it more attractive to be slightly rather than dramatically altered by a drug.
Nicotine enables the smoker to remain useful and functional during a normal day.
In individuals prone to depression, such a neutral emotional state is highly desired and, perhaps, only achieved through the use of drugs. Nicotine dependence in the smoker with a history of depression may be particularly difficult to combat. Depression hampers smoking cessation When an individual attempts to quit smoking, mood changes are one symptom of tobacco withdrawal. For individuals who are currently depressed or are more susceptible to depressive symptoms, such mood disturbances may be more severe. These factors may help explain why smoking cessation success rates are significantly lower among individuals with a history of major depressive symptoms.