When beta-glucoronidase breaks the bond, the freed hormone is available to be reabsorbed back into the body instead of being excreted. As a result the body is better able to get rid of excess hormones like estrogen. The preliminary results are quite encouraging. Currently, calcium D-glucarate is being studied at the National Cancer Institute in clinical trials as a preventive measure for breast cancer. Calcium D-glucarate may emerge has a better choice for women with a history of breast cancer than the currently prescribed drug tamoxifen to block estrogen receptors.
Tamoxifen is associated with numerous side effects.
In contrast, calcium D-glucarate is completely safe and, if preliminary results hold true, it may also be more effective. The recommended daily dosage for prevention is 200 to 400 mg.