Fibrosis is the deposition of connective tissue in internal organs. 5-HTP along with chronic alcoholism and liver disease caused heart fibrosis in animals. Alcohol inhibits the metabolism of 5-HTP . 5-HTP can increase the effect of tranquilizing drugs and can impair the ability to drive an automobile. In other words, it is not an absolute contraindication.
Physicians sometimes use substances which have an interaction to accentuate the effect.
This may be one of those times and should not be the subject of self-experimentation. Combine these only under the supervision of a health professional. DOSE Start with one capsule daily. Then after two weeks move to one capsule twice daily. If this is inadequate then one capsule 3 times daily may be tried.