The downside is everything can and will change from time to time. There is no such thing as a typical trip. Another aspect I myself enjoy. Instead of flying the Boston-JFK run three times a day, I might go from Atlanta, to Washington, to Palm Springs. Then the next day off somewhere else.
Variety is the spice of life.
The parts I like best is that it is so varied. I'm also the one in charge. If faced with a problem, I don't call operations and have people make decisions for me. I'm really my own boss. I enjoy the challenge of the job.