Symptoms and ailments We'll focus this discussion on symptoms, since that is where most people begin when they suspect that their guinea pig is ill. Again, this is not intended to be a replacement for competent veterinary care, but rather as an introduction to common afflictions. Some sneezing is actually normal for guinea pigs, though excessive sneezing could be the sign of a respiratory complaint. Certainly, any time you see discharges from the nose, or the guinea pig regularly wiping its nose, it is most likely related to a respiratory or sinus infection. It is also possible to have a fungal infection in the nasal passages, but this is more rare.
Some guinea pigs are even allergic to certain hays, including timothy.
Coughing Like sneezing, some coughing is normal in guinea pigs. Most of the time, coughing is brought about by a minor irritation in the windpipe, possibly caused by inhaling dusty hay or something similar. More serious would be constant coughing, which could be the sign of an infection or illness. Kennel Cough, in particular, is a rather serious illness in guinea pigs, and can actually be transmitted between species, including dogs, rabbits and guinea pigs. If any coughing is accompanied by other respiratory problems, particularly wheezing, then it is most likely a sign of a respiratory infection.