It can affect any organ system. No curative treatment is known. Systemic steroids are usually used. This is a disease of the skin of the nose characterized by chronic inflammation and hypertrophy, producing a large, red, violaceous nasal tip and comedones. Histology shows sebaceous gland hypertrophy, scarring, acanthosis, and frequent telangiectasia.
Treatment is surgical excision.
Venereal spirochetosis caused by Treponema pallidum. Primary syphilis of nose is rare, occurring 3-4 weeks after contact as an indurated, painless ulceration at mucocutaneous junction or septum accompanied by disproportionate adenopathy. Secondary syphilis appears as widespread erythematous papulosquamous eruptions, lesions and patches, and condylomas. Treatment is penicillin.