This can lead to up to an order of magnitude improvement in computational efficiency. The program allows visualisation and manipulation of both protein and DNA sequences. Verbumculus - A tool for the fast discovery and visualization of unusual words in genetic sequences. ESPript - ESPript is a utility, whose output is a PostScript file of aligned sequences with graphical enhancements. Its main input is an ascii file of pre-aligned sequences.
Optional files allow further rendering.
The program calculates a similarity score for each residue of the aligned sequences. Data generated can be as simple as a single sample of random individuals with a single normally distributed trait or as complex as thousands of samples of extended families with multiple traits based on a linear combination of major locus, polygenic, common sibship environment and covariate components. Traits can be generated based on a number of user specified components, and components can be unique to a single trait or shared by multiple traits. Only two loci can be handled at a time, for example, a disease locus and a marker locus. In addition, it can be used to obtain estimated breeding values and fixed effects solutions.