Isoxaben, a relatively new broadleaf preemergent herbicide, has been effective in limiting germination of plantain in turfgrass. For established plants, 2,4-D works best while triclopyr, MCPA, and mecoprop will only reduce its vigor. Best control is achieved from a fall application. Repeat applications are needed to kill weakened perennial weeds and new germinating seedlings. There are few options for the control of plantain in ornamental plantings.
Prevention is very important.
Hand-removal or spot treating of solitary plants with glyphosate will save time and money in the long run. Pulling or hand-hoeing is helpful if done periodically during the year. However, regrowth from the extensive crown system limits the effectiveness of this method. Mulching with landscape fabrics can be effective for controlling seedlings of both species. Even established broadleaf plantain can be controlled if the fabric is overlapped and no light is allowed to penetrate to the soil.