Some veterinarians require your signature on a release form before using a nonUSDA approved product so that there is a clear understanding of client responsibility in case of an adverse reaction. In addition, the drug companies that produce these flea control drugs are not liable for the product's use outside of the recommended species and should not be held responsible if a problem occurs. It is highly unlikely that any of these products will acquire official USDA approval for use in rabbits because the process is extremely time consuming and expensive. The information in this article is based on my own experience as well as that of several other exotic animal veterinarians and does not represent scientifically produced data. As mentioned, always check with your veterinarian before trying any new product to insure that it can be used safely on your individual pet.
Rabbits have very thin and sensitive skin.
This must be taken into consideration when using topical products because they can cause a localized dermatitis or be absorbed directly through the skin and cause an internal toxic reaction. In addition, if the rabbit can reach the area where the product is applied, he may lick it during grooming activities and ingest toxic amounts of the material. Whenever you use a new product on your pet, please observe him closely for 24 hours following application for signs of toxicity. If you observe any of these signs, wash the product off the rabbit immediately, using mild soap and copious amounts of water, and call your veterinarian for further instructions. Keep all flea products and soaps away from the rabbit's eyes, ears and mouth.