An autosomal dominant disease.
Polyps start to appear in the second to third decades of life.
Prophylatic colectomy is the method of choice for preventing development of adencarcinoma of colon. Grossly, there are numerous adenomatous polyps in the colon. Microscopically, the adenomatous polyps show the same morphology as any other adenomatous polyp. Each polyp has a fibroconnective core and is lined by glands and a surface epithelium.