Recessive - multiple vertebral segmentation defects iv. Prominant or bulging forehead with widely spaced eyes iii. Short, upturned nose with anteverted nostrils and flat nasal bridge iv. One parent is carrier of a dominant gene that produces the syndrome ii. Children born with the recessive version have more marked dwarfism, radial head dislocation, shorter limbs, shorter fingers and toes and spinal segmentation defects.
Recessive cases appear to have more of the skeletal abnormalities.
A. Urinary i. Psychosocial problems related to appearance are an issue. Normal to borderline adult height in dominant forms. Recessive forms will have more marked dwarfism. C. Procreation Fertility and reproduction have been documented in females with both forms of the syndrome.