The low buzz is sounded when a contestant runs out of time, or guesses incorrectly. These things all lead to losing. Another negative sound occurs when a contestant lands on the bankruptcy slot. This specific sound reminds me of the old roadrunner and coyote cartoons, when an anvil falls off a cliff, and lands on the coyote's head. Obviously, this is not a good sound.
Technical characteristics are an important part of any show.
Tight close-ups of Vanna and Pat are emphasized to hold the attention of the viewers. I also think this technique is used to remind the viewers of the celebrity element of the show. Another emphasized characteristic is the sounds that are used. Each buzzer and dong serve a purpose and keep the viewer informed on what is going on throughout the show. Not all characteristics are emphasized.