These findings suggest that NO acts as an essential negative regulator of cell number during development by controlling the balance between cell proliferation and cell differentiation. We are now focusing on genetic and molecular interactions of NO with systems that control cell division and cell differentiation in the developing and adult organism. Selected Publications Peunova, N. and G. Enikolopov. 1993. Amplification of calcium-induced gene transcription by nitric oxide in neuronal cells. Peunova, N. and G. Enikolopov.
Nitric oxide triggers a switch to growth arrest during differentiation of neuronal cells.
Kuzin, B., I. Roberts, N. Peunova, and G. Enikolopov. Nitric oxide regulates cell proliferation during Drosophila development. Enikolopov, G., J. Banerji, and B. Kuzin. Nitric oxide and Drosophila development. Cell Death and Dif .