Pain in involved joints 2. Pain worse with activity, better with rest 3. Limitation of joint mobility with periarticular muscle atrophy 8. Joint instability B. Joints typically involved 1. May occur in younger individuals 3.
Radiographs often show changes that appear more severe than clinical findings.
Patients with primary generalized OA may have debilitating symptoms. B. Erosive inflammatory osteoarthritis 1. DIPs, PIPs, 1st CMCs, 1st MTPs 3. May be acute flares but later acts like more typical OA 5. ESR, RF, ANA negative C. Secondary OA 1.