Forni et al. Multiple Organ System Failure. Reduced tissue perfusion caused by systemic hypotension causes problems for many organs, including the brain, where cerebral edema leads to headaches, disorientation, and confusion. In a clinical setting, reduced blood volume and dehydration from diarrhea and vomiting require massive fluid replacement that eventually damages the kidneys, causing renal failure , and in some cases respiratory distress . Lack of Purulence.
Solid lines indicate known effects, broken lines indicate putative relationships.
Image created by author. A Streptococcus 1. from a sterile site 2. from a nonsterile site B. Clinical signs of severity 1. Literature Cited Bohach GA, Fast DJ, Nelson RD, Schlievert PM. 1990. Staphylococcal and streptococcal pyrogenic toxins involved in toxic shock syndrome and related illnesses. A streptococcus infections and streptococcal toxic shock syndrome.