Our suites give you fifty percent more space than a traditional hotel room. The Residence Inn Portsmouth is adjacent to the Redhook Brewery, one mile from Fox Run Mall, two miles from Liberty Mutual and Newmarket Software and three miles from downtown Portsmouth. Online reservations and availability. Online reservations and availability. Sheraton Harborside Hotel Portsmouth Located in the heart of the downtown historic waterfront area, the Sheraton Portsmouth Hotel is within walking distance of shops, boutiques, area restaurants and regional entertainment.
Moments away are Maine and New Hampshire beaches, as well as outlet shopping, golf and tennis.
Whale watching cruises depart across from the hotel. Online reservations and availability. Online reservations and availability. Sise Inn Located in the heart of historic Portsmouth, Sise Inn was originally the home of prosperous businessman and merchant John E. Sise and his family. Guest and public rooms are decorated in Victorian style, using antiques, period reproductions and museum prints.