Viral antigen localizes immunogistochemical to dendrites and axons. Neurofibrillary tanges are seen late in symptomatic patients. Some patients' symptoms stabilize in Stage III for up to 2 years. Nonetheless, almost all patients die within 10 years of the initial symptoms. The incidence of SSPE varies throughout the world.
Regional disparity is most likely due to variable early childhood rubeola immunization.
Yalaz, K., B. Anlar, F. Oktem, et al.