The goals of treatment are to cure the infection and reduce progression of the disorder. Treatment of the infection will reduce new nerve damage but will not cure existing damage. Penicillin or other antibiotics such as tetracycline or erythromycin are given to treat the infection. Treatment may be prolonged to ensure that the infection is completely cleared. A follow-up examination of the cerebrospinal fluid is required to evaluate the effectiveness of antibiotic therapy.
Symptomatic treatment is required for existing neurologic damage.
Emergency treatment of seizures may be required. Anticonvulsants such as phenytoin may be needed to control seizures. Assistance or supervision with such activities as eating and dressing may be needed if patients are unable to care for themselves. Physical therapy, occupational therapy, or other interventions may be appropriate for people with muscle weakness . Progressive disability is likely.