With its rich, fertile land, Audrain is one of Missouri's leading agricultural counties. Its main crops are soybeans, corn, grain sorghum and wheat. Once a national center for saddle horses and mules, it now produces mainly hogs and cattle. Of major importance to the county is the refractories industry. In addition, the county claims several small manufacturing firms and service industries, along with many small businesses.
Residents enjoy an economic climate marked by variety and progress.
Education and related pursuits have long held an honored position in the county. Three consolidated public school districts serve most of its children. It has a number of other educational institutions and is home to one of the nation's Exemplary Private Schools, Missouri Military Academy. Mexico's Vocational and Technical School and its Advanced Technology Center, now being built, offer students many opportunities. The Mexico-Audrain County Library District serves residents through its main building at Mexico and four branches across the county.