The grant involves a series of interactive research projects focused on expanding our understanding of the pathogenetic significance of these molecules in breast cancer progression, and exploiting this information to develop effective new strategies for breast cancer prevention and treatment. Prognostic factors and therapies involving these breast cancer gene products are utilized in preclinical and clinical studies. The five shared resources supporting this program include a tumor bank of fresh and frozen breast tumor materials, a transgenic mouse facility, a repository of breast cancer cell lines, clinical breast cancer research resources, and a serum and plasma bank. The goal of the program includes the development of individuals having the capability to move basic research findings into applied research settings with patients and populations.
Postdoctoral positions are immediately available.
Successful applicants will have the opportunity to choose a mentor from among an interactive group of peer reviewed and funded investigators who are currently committed to breast cancer research. Research programs cover the development of novel anticancer therapies, evaluation of prognostic indicators, dissemination of the genetic and molecular mechanisms that underlie the malignant progression, prevention models, loss of estrogen sensitivity, and increased metastatic potential of breast cancer cells. Complete descriptions of individual research programs are available upon request. Salary is competitive and commensurate with qualifications and experience. Applications from women and minorities are encouraged.