In addition, these agents modify the body's immune response to diverse stimuli. Antihistamine - Act by competitive inhibition of histamine at the H1 receptor. Mediates, bronchial constriction, mucous secretion, smooth muscle contraction, edema, hypotension, CNS depression and cardiac arrhythmias. Usually safe but benefits must outweigh the risks. Pregnancy B - Usually safe but benefits must outweigh the risks.
Mechanism of action is unknown.
Etretinate is main metabolite and has demonstrated clinical effects close to those seen with etretinate. Mechanism of action is unknown. Vesicular and hemorrhagic lichen nitidus. Improvement of lichen nitidus after topical dinitrochlorobenzene application. Familial lichen nitidus.