This often causes heartburn, vomiting, and esophageal irritation from stomach acid. It also causes an increased risk for aspiration pneumonia. About one-half of individuals with Lowe syndrome have constipation. Poor muscle tone may contribute significantly to this problem. Some doctors believe, however, that constipation is a specific feature in Lowe syndrome and represents a direct effect of the gene upon the intestinal muscles, causing an inability to move the stool effectively.
Treatment includes adequate amounts of fiber in the diet and plenty of water.
If dietary control is ineffective, medication may need to be considered. This should be done only under a physician's care. Enemas are not recommended because they can lead to serious metabolic imbalances that could be life threatening. Cysts, a common problem in Lowe syndrome, can occur in many places, including the mouth, kidneys, brain, and skin. Dental cysts appear to be quite common with teething but usually resolve after permanent teeth are in.