Return to top Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue using Differin. Side effects are most likely to occur during the first 2 to 4 weeks and usually diminish with continued treatment. If side effects are severe, your doctor may advise you to reduce the frequency of use or discontinue the drug entirely.
Side effects disappear when the drug is stopped.
Return to top Do not use Differin if you are sensitive to adapalene or any other components of the gel. If you have an allergic reaction or severe irritation, stop using the medication and call your doctor. Remember that Differin increases sensitivity to sunlight. Take measures to protect yourself from overexposure. Wind and cold weather may also be irritating.