Wisdom is a perfect knowledge. This fact tells us immediately that in knowledge there are degrees of perfection. When we have the Faith, and we thank God if we do, we know some tremendous truths - e.g. the truths we proclaim in the Apostles Creed which we recite daily to start the Rosary. We know these truths with absolute certainty, and yet the knowledge of Faith is not as perfect as the beatific knowledge of the blessed in heaven. It is said of St. Teresa of Avila, to take one example, that she almost had the Beatific Vision, that in her mystical life there remained just one thin veil keeping her knowledge of Faith from becoming the full and perfect knowledge of vision.
Wisdom is the most perfect knowledge of the most important truths.
This lets us know that there is a hierarchy in the order of the sciences and the whole realm of knowledge. Our Church is hierarchical, and as Catholics we know that our universe is also hierarchical, and that there is a hierarchy of value in all things. All knowledge is good and desirable, but there is a knowledge of trivialities and a knowledge of very important matters. There are very important truths revealed by God that we must accept on the authority of God revealing and the Church teaching in His name. All these truths and many others, especially those pertaining to the Blessed Virgin Mary, Her Immaculate Conception, Her Assumption into Heaven, etc. could never be known by men if God had not revealed them.