Also assault aberrant cells that could form tumors. Are not phagocytic, but attack the membrane, causing cell lysis. 1.The inflammatory response is triggered by damage to tissues caused by physical injury or by microbes. Small blood vessels near the injured site dilate and become leakier, causing the redness, heat and swelling associated with infection. Migration of phagocytic white blood cells is enhanced.
Neutrophils arrive first, followed by monocytes that develop into macrophages.
3.Clotting proteins pass into the interstitial fluid to seal off the infected area and begin the repair process. 4.Injured cells emit substances that aid in the inflammatory response. Histamine induces dilation of neighboring blood vessels. Leukocytosis-inducing factor stimulates release of neutrophils from bone marrow. 5.The inflammatory response may include systemic reactions.