Social engineering is typically employed to trick a recipient into executing the malicious file. The best advice with regard to malicious files is to avoid executing them in the first place. The virus can cause your system to be unstable until it is repaired. The system might be unstable and not work properly until the virus is removed from the computer. Please be careful of viruses at all times, but especially during the Holiday season when people might send you attachments which are supposed to be interesting or decorative.
Most packages have a way to automate the virus update process.
Your department's technical staff can help you check your software and plan for any renewals if needed. You know the name of the attachment. You know exactly what the attachment does when opened. If you receive unsolicited attachments, please do not open them. If you are unsure what the attachment does, contact your departments' technical staff or contact the Computer Services Help Desk.