Nucleases are phosphoidesterases with a tremendous variability in their substrate requirements.
Some endonucleases comprise site-specificity and require distinct sequences for cleavage others require helper proteins to find their targets. The development of phage T4 depends on a series of self coded DNAses. 49- DNA suggested that the packaging process was physically interrupted by frequently ocuring branches as they were made during replication or recombination earlier during the infection cycle. Homepage B.Kemper , Inst.