The mind and externals are just thus, the gate of liberation is open. The Third Grave Precept is honor the body - do not misuse sexuality. Honor the body of Nature. When we begin to interfere with the natural order of things, when we begin to engineer the genetics of viruses and bacteria, plants and animals, we throw the whole ecological balance off. Our technological meddling affects the totality of the universe and there are karmic consequences to that.
Nothing is desired.
Go the same way as the Buddha, do not misuse sexuality. The Fourth Grave Precept is manifest truth - do not lie. One of the very common kinds of lying that is popular these days is called green-washing. You hear Monsanto Chemical Company tell us how wonderful they are and how sensitive they are to the environment. Exxon tells us the same thing.