Methotrexate may damage sperm and may harm the baby if used during pregnancy. It is best to use birth control while being treated with methotrexate. Tell your doctor right away if you or your partner becomes pregnant. Do not breast feed during treatment. Tell doctors or dentists that you are being treated with methotrexate before you receive any treatment from them.
Most people have little or no nausea.
Eat often in small amounts. Pain or tenderness may occur where the needle was placed. Apply warm compresses for 15-20 minutes several times a day. Numbness or tingling in your fingers, toes or face. Changes in eye sight.