In a person who already has a mental illness, cannabis can trigger psychotic episodes. Tolerance and dependence With regular use, people can develop a mild tolerance to cannabis. This means they need to take more and more to get the same effect. Dependence on a drug can be psychological or physical or both. This means that using cannabis becomes far more important than other activities in their life.
Some people crave the drug and find it very difficult to stop using it.
The body gets used to functioning with the drug present. Heavy and frequent use of cannabis can cause physical dependence. Withdrawal Abrupt termination of cannabis use can produce a mild withdrawal syndrome. Symptoms include sleep disturbance, irritability, loss of appetite and consequent weight loss, nervousness, anxiety, sweating and upset stomach. Sometimes chills, increased body temperature and tremors occur.