Do not give this drug to people who have not researched it beforehand. It should not be used if you are pregnant, nursing, or not of a mature emotional level. These variables are true of all psychedelics. Personally, I have found that the best setting is at home with the lights dimmed, playing mellow music and hanging out with loved ones. Generally, the effects build for roughly 2 hours, at which point you reach the peak and gradually float down for about 4-6 hours more.
Some users report insomnia following the journey.
Cross-tolerance with LSD has also been reported. Many people have commented that at this dosage range it possesses wonderful aphrodesiac qualities. As the dosage increases past the 10mg mark, the effects become increasingly psychedelic, producing vivid visuals and mental phenomenon similar to LSD or Psilocybe mushrooms. However, even though the amount of material is quite small, the burn is quite signifigant and the taste from the post-nasal drip is extremely unpleasant. This route, like the insufflated route, offers the advantage of a shorter and less nauseous journey.