Guilt is the same thing on a relational level. It's your heart's way of telling you something is wrong which needs to be fixed. Nobody likes to feel guilty, but if you become so insensitive, if you are numb to the people around you, you won't even know you're doing damaging. You won't even realize you're killing off the very relationships that give you life. Listen, salvation comes by relationship.
Some people run from guilt, because of the shame they feel.
They can't admit they've done wrong because it makes them feel so bad about themselves, and they already feel so bad about themselves, they can't take any more. So they blame somebody else. Or they plead extenuating circumstances. Or they accuse the other of doing worse to them. Anything to escape the guilt they feel, anything that is, except taking responsibility, making amends, and refusing to do wrong again.