Tumor is to the right and renal parenchyma is on the left. The stage and the presence of anaplasia, which tends to occur in older, nonwhite patients, affect the prognosis of the disease. Other prognostic factors are large tumor, capsule penetration, and spillage of tumor into the abdominal cavity. The tumor is sensitive to both radiation and chemotherapy. Combined surgical resection, radiotherapy and chemotherapy have improved prognosis dramatically.
Patients dying of the tumor almost always do so within the first two years.