Pentoxifylline inhibits mediator synthesis in an equine in vitro whole blood model of endotoxemia.
Increased phospholipid mass with decreased arachidonoyl molecular species is associated with decreased eicosanoid synthesis and increased tumor necrosis factor synthesis by thioglycollate elicted rat peritoneal macrophages. Dietary source of omega-3 fatty acids effects endotoxin induced peritoneal macrophage TNF and eicosanoid synthesis. Changes associated with diagnosis, surgery, and outcome. Vet Intern Med. Vet Med Assoc, in press.