For vessel entry use self contained or supplied air respirator with full facepiece. Where splash or mist potential exists, wear chemical worker's goggles and butyl or nitrile rubber gloves. Other protective equipment such as aprons, rubber boots, face shield, or rubber suit may be needed. Eye wash stations and safety showers should be readily accessible near use areas. Employees who handle dimethyl sulfide should wash their hands before eating, smoking, or using toilet facilities.
Material can react with strong oxidizing agents.
Pre-existing respiratory diseases may be aggravated by exposure. LD 50 data can be found. The greatest danger from a spill is fire. DMS is part of the natural reduced sulfur cycle and as such is not expected to cause any long term ecological damage. Small quantities of DMS can be destroyed by treatment with dilute household bleach.