Reactive lymphocytes in the peripheral blood may also be found. Special molecular tests are necessary to confirm this disease and may take one week to get the results back. Giving T-lymphocytes from the donor to the patient is often curative and is done most often. Higher doses of ganciclovir, alpha-interferon and daily immune globulin may be given. Surgical resection of the tumors and radiation to localized areas are rarely indicated.
Prevention is easier than treatment.
Intranasal and IV amphotericin-B and fluconazole are used prophylactically to prevent fungal infections. Sometimes exposure occurs prior to transplant but causes no problems until after the ablative therapy has decreased the patients ability to fight infection. The special hepafilters in the BMT unit are designed to filter the air clean and prevent aspergillus from being acquired during the early time period following the transplant. Depends upon the organs involved. Pulmonary aspergillosis may present with fever, cough or sinusitis.