With a history of severe penicillin allergy e.g. anaphylaxis, it would be inadvisable to use a cephalosporin if a suitable alternative were available.
Oral penicillin given for ten days is equally effective.
There are numerous preparations of injectable penicillins available in the pharmacy. The six hourly regimen is usually adopted for practical reasons but the four hourly regimen is more appropriate in view of the short half life of penicillin. Infections at other sites may require higher doses of amoxycillin. This should be achieved by combining 250mg amoxycillin with 375mg co-amoxiclav thus providing 500mg amoxycillin with 125mg clavulanic acid. A composite 625mg co-amoxiclav tablet is now available in S.A. but is more expensive.