DNA sequences and associated annotation, protein homologies and sequence motifs are obtained from the two sequence databases, one in Sanger Centre, the other in St. These contain the finished sequences of cosmids selected for analysis by the C. elegance Genome Sequencing Consortium, made up of the two laboratories. Additional DNA sequences are extracted from the EMBL database. It contains the contigs, yacs and cosmids already mapped, many of which have also been sequenced. Contents of the quarterly Worm Breeders Gazette and annual worm meetings are obtained from a worm centre in Texas run by Leon Avery.
Raw data is converted using perl scripts into a format readable by the database - ace format.
Approximately monthly, the database is dumped out to prepare a set of files containing all the information appended since the last update. These update files are placed on the Sanger ftp server and mirror sites, and notification sent to interested parties. The worm and mouse ACeDB databases are demonstrated on the General computing courses run in University vacations. Angler Information regarding Angler software is available here.