Recent studies of the biology of prostate hyperplasia suggest that this drug might also ease the passage of urine. The study, directed by Glenn Gerber, M.D., assistant professor of surgery at the University of Chicago, will analyze the effects of the drug on BPH symptoms and on urinary flow.
Participation requires three clinic visits over the course of three months.
At the beginning and end of the trial, volunteers will undergo routine tests for assessing BPH, as well as a urodynamic study that involves inserting a thin tube through the penis into the bladder, filling the bladder with fluid and measuring the flow of the fluid as the patient urinates. Although side effects from doxazosin are uncommon, some users have complained of lightheadedness, dizziness and fatigue, symptoms which are often associated with drugs that reduce blood pressure. Side effects associated with the urodynamic study include possible irritation of the urethra and, rarely, bleeding or infection. The medication will be provided for free. The study, under the direction of Dr. Glenn Gerber, requires three clinic visits over the course of three months, routine tests for assessing BPH, as well as a urodynamic study .