This is a somewhat fancy phrase for feeling that you don't care, that life is too much, that you don't have the energy to confront your next task.
Nothing seems to matter very much.
You are bored. You don't want to listen to another person, attend another meeting, fly off to yet another conference. Things seem stale, so what is the point of more discussion, you may ask yourself. It feels as if you are in an endless tunnel, performing the same tasks over and over, that there is no reason for what you do nor no end in sight. It feels hard to care about anything or anyone.