Although there is no cure for Lewy Body disease it is sometimes possible to treat some of the symptoms of this disease. The depression which accompanies this disease for example will usually respond to antidepressant therapy. This disease may be of senile or pre-senile onset. There is loss of cells in the speech areas of the frontal lobe. The disease is difficult to distinguish from Pick's disease during life.
Mental impairment occurs late in the course of the disease but some patients lose language early.
Post mortem changes include fronto-parietal atrophy and subcortical loss. There are swollen cells similar to Pick cells but no Pick bodies. This disease usually affects people in their 60's to 80's. Males and females are equally affected. A disease affecting the brain stem.