Although there is no convincing evidence documenting adverse effects of inactivated poliomyelitis vaccine on the pregnant woman or the developing fetus, it is prudent on theoretical grounds to avoid vaccinating pregnant women. However, the systemic reactivity associated with administration of DPT Adsorbed in previous clinical trials would tend toindicate that the DPT Adsorbed was the major contributory factor. In infancy the primary schedule is usually integrated with DPT Adsorbed immunization, beginning at 8 to 12 weeks of age. 8 weeks apart, followed by a third dose of 0.5 mL, approximately 12 months after the second dose. Further recall doses of 0.5 mL should be given every 10 years thereafter.
Most adults are already immune and have a very small risk of exposure to poliomyelitis.
Therefore, prior to use of the live, oral poliovirus vaccine for immunization of a family member, some health care personnel recommend that adults who have never received any polio vaccine should be given at least 2 doses of Inactivated Poliomyelitis Vaccine a month apart, or preferably,the full primary series. The vaccine should be administered by s.c. injection. The injection may conveniently be made into the s.c. The site of injection should be prepared with a suitable antiseptic. A separate sterile syringe and needle should be used for each individual patient to prevent transmission of hepatitis viruses and other infectious agents.