Both UVB and UVA can produce tanning. Exactly how UV light aggravates lupus is unknown. Research suggests it alters DNA and protein in the skin. The altered DNA may act as an antigen that triggers the autoantibodies and provokes an autoimmune response in the skin. The skin reacts to these substances, becomes red, inflamed and develops a rash.
Photosensitivity reactions can also affect the internal organs.
There, they may cause inflammation in organs and lead to systemic symptoms. Injury to people with LE in the workplace can be a cause for worker's compensation and litigation. Each case must be individually studied and expert opinion obtained. There is no question that individuals who have lupus and are photosensitive should avoid excessive sun exposure. Delivering the mail, construction work, and lifeguarding are examples of occupations that may receive excessive sun exposure.