The cause of hemorrhage seen in these livers may be related to the more friable nature of the mineralized tissue. Metastatic calcification occurs most often in guinea pigs over 1 year of age. Dietary factors such as low magnesium and high phosphorous and calcium intake have been implicated in this syndrome. High calcium or high phosphorous diets appear to interfere with magnesium absorption and metabolism. Diet composition and mineral balance in guinea pigs.
Vomit comprises white froth which is sometimes bile stained.
Two days ago developed tender soft tissue swellings in the region of the submandibular salivary glands. Acute to subacute idiopathic salivary gland necrosis. Subtotal to total apparently ischemic necrosis of the mandibular salivary glands in the characteristic histologic finding in a sporadic disease of terrier-type dogs, notably of the Jack Russell breed. However, unlike the situation in dogs, in people necrotizing sialometaplasia generally affects the intraoral minor salivary glands and also, in our experience, ductal metaplasia has not been a distinctive feature of the canine lesion. In subtotally affected glands, the margin between affected and unaffected tissue is delineated by a band of fibro-vascular tissue accompanied by a mild infiltrate of inflammatory cells.