The efficacy of omeprazole used for longer than 8 weeks in these patients has not been established. In the rare instance of a patient not responding to 8 weeks of treatment, it may be helpful to give up to an additional 4 weeks of treatment. Maintenance of Healing of Erosive Esophagitis Omeprazole delayed-release capsules are indicated to maintain healing of erosive esophagitis. Controlled studies do not extend beyond 12 months. The recommended adult oral dose of omeprazole is 20 mg once daily.
Most patients heal within four weeks.
Some patients may require an additional four weeks of therapy. Combination therapy with clarithromycin. The recommended adult oral dose is 40 mg once a day for 4-8 weeks. The recommended adult oral dose for the treatment of patients with symptomatic GERD and no esophageal lesions is 20 mg daily for up to 4 weeks. The recommended adult oral dose is 20 mg daily.