1 Active ulcer recurrence is frequent.
Surgical therapy is sometimes necessary.
Death can occur in PUD from bleeding or perforation. 2,3 Helicobacter pylori has also been implicated as a putative agent in the development of gastric malignancies. 4,5 Testing methods for HP are both sensitive and specific. Epidemiologic studies have found HP to be prevalent, particularly in the elderly. Eradication of HP has been associated with both increased ulcer healing rates and markedly decreased recurrence rates.