Stehekin is, in my opinion, almost too isolated and quiet. They look close on a map but they are not. Haven't personally hiked out of the region but it looks great. A LONG drive from Seattle to Hannegan Road yields a rapid alpine view of the north face of Mt. Shuksan and distant views into the rugged north cascade range proper. DO NOT skip hiking the peak.
Mt. Ruth is shown on the left.
As you can see, the weather crapped out on us. This shamefully unprotected region is one of the most stunning in the area. Expect HUGE crowds as a result of this combination of attributes.