This page has moved. Click here to view. Urticarial Vasculitis Urticarial vasculitis is a subset of vasculitis characterized clinically by urticarial skin lesions and histologically by necrotizing vasculitis. There is a spectrum of clinical and laboratory features urticarial vasculitis, urticaria, hives, urtacaria.
Many patients have minimal signs or symptoms of systemic disease.
Urticarial vasculitis plaques persist for 24 to 72 hours and may have residual changes of purpura, scaling, and hyperpigmentation. The lesions are burning and painful rather than itchy. Fragmentation of leukocytes and fibrinoid deposition occur in the walls of postcapillary venules, a pattern called leukocytoclastic vasculitis . There is an interstitial neutrophilic infiltrate of the dermis. Anti-C1q autoantibody develops in disorders characterized by Patients with hypocomplementemia may have an immunofluorescent pattern of immunoglobulins or C3 as determined by routine direct immunofluorescence.