The label is part of the registration. The label provides use directions and other pertinent information for applicators. Commercial introduction . A product must bear an EPA-approved label before the registrant can introduce it for sale in the United States. State application .
Most states require manufacturers to register all products used within that state.
Several states utilize unique registration processes similar to those of the EPA registration process. Any unexpected adverse finding, either toxicological or environmental, during product development ends the testing even if several years and several million dollars have been invested. For this reason, manufacturers are alert to recognize and acknowledge problem products early in the developmental process in order to minimize costs. On the average, only one in 35,000 chemicals survives from the chemist's laboratory to the market. The special review process is the mechanism that provides EPA the regulatory flexibility to reevaluate the registration of a pesticide.