Samples are collected no earlier than five days, nor later than six weeks after onset. Viral RNA can be detected by specific complementary DNA probes or amplified first by polymerase chain reaction. Treatment is supportive with acetaminophen rather than aspirin for fever and pain relief, bed rest, fluid replacement, and gradual convalescence. Increased capillary permeability limits the extent of fluid replacement. Pressors may be required to maintain blood pressure.
Renal failure requires dialysis.
Dengue hemorrhagic fever and shock syndrome are medical emergencies treated in intensive care settings. Rift Valley fever. W.B. Saunders Company.