The influence of atopy has not been discussed. Sensitization occuring during water treatment or the manufacture of the chemicals. A case of hyperthermia associated with the asthma has been described. Very dry tobacco leaves are the most dangerous. Subjects are not always atopic.
Tobacco smoking plays an aggravating role.
Subjects become sensitized by the inhalation of dried tobacco leaf debris. Rhinitis and asthma with tightness of the chest, acute, sometimes violent dyspnoea. Diagnosis References Skin prick test with a tobacco leaf extract. J. of Med. J. Ind. Med.