Many are manufactured in skin-colored tones to help hide blemishes. Salicylic acid preparations help unclog pores and are especially effective against blackheads. Benzoyl peroxide preparations help dry acne on the skin's surface as well as underneath. Prescription topical medications Antibiotics containing clindamycin or erythromycin can help reduce inflammation by killing acne bacteria.
Sodium sulfacetamide inhibits bacterial growth.
Some combination therapies pair antibiotic and antibacterial agents. Drawbacks of prescription topical medications can include skin irritation, drying and sensitivity to sunlight. Systemic medications Oral antibiotics including tetracycline, erythromycin and minocycline can kill acne bacteria, reduce the amount of facial oil and relieve inflammation. Hormonal therapy and corticosteroid therapy are sometimes used to suppress production of male hormones in female patients who have not responded to other treatments. Drawbacks of systemic treatments can include stomach upset, skin irritation and dryness, and sun sensitivity.