In particular, her ankles were swollen and her elbows were tender. That morning she had developed a purpuric rash over her lower limbs. She was afebrile. There was no previous history of a sore throat. Answers Henoch-Sch nlein purpura.
Purpura are small circumscribed lesions caused by bleeding into the skin.
Causes may be divided into thrombocytopenia, vascular defects, coagulation abnormalities, and drugs. Abnormalities of vessels include Henoch-Sch nlein purpura, senile purpura, scurvy, uraemia, and gonococcal arthritis. Iatrogenic causes include anticoagulation or steroids therapy. Men are more commonly affected than women. The condition was first described in 1808 by Willan, but it was Eduard Heinrich Henoch, studying under Johannes Lucas Sch nlein, Professor of Medicine, in Berlin, who reported the link between gastrointestinal symptoms and a purpuric rash in 1874.