Dental abnormalities include hypodontia or oligodontia, delayed eruption, malocclusion, and small teeth with dysplastic enamel. Supernumerary nipples, hypoplasia or aplasia or the clavicle, split sternum, and rib abnormalities. Scoliosis and spina bifida. Scalp and pubic hypotrichosis and absent, spooned or grooved toenails and fingernails. Hydronephrosis, bifid ureter and kidney pelvis, horseshoe kidney, hypoplasia of the labia and clitoris, and cryptorchidism.
Some cases are familial and are transmitted as an X-linked dominant trait lethal in males.