It won't happen unless somebody does it. Tolerance - we must be able to accept other visions, other paths. If some people will not walk along our path it is their choice and nothing we should worry about as long as they do not seek to hinder us. Optimism - our culture has the last decades become ever more pessimistic, careful and apathetic. To be able to develop one must dare to enjoy oneself.
Pessimism breeds apathy, optimism action.
Freedom - we need freedom, not just political and social freedom, but also freedom from material limitations. Reason - we need to let ourselves be guided by reason, by critically testing old and new ideas in order to avoid being blinded by our optimism or the pessimism of the Cassandras. Without reason we will wreck ourselves, without our visions we will lack direction. If we can combine these five elements the transhuman vision becomes feasible - and the foliage of creation will spread its branches among the stars.