There is a need to include high risk pregnancies, those with limited access to health care, and women in the first 6-8 weeks of pregnancies. Confidentiality approach should reflect balance between maximum confidentiality and data utility and legal obligations, e.g., reporting child abuse. Time, cost, burden, etc. should be considered in selection. Need models to predict exposure, dose and target tissue dose. Technology-Outcome Outcomes should also be examined by life stage.
Special expertise is needed to complete the matrix.
Also, new data analysis techniques should be considered, e.g., new statistical methodologies, use of multiple, linked computers for analyzing large data sets, and GIS methods. Need valid diagnostic criteria and screening methods to identify subgroups for more detailed measures. Outcome measurements should be standardized- nomenclature, protocols, methods, and archives. Archiving specimens is especially important. Need to measure both short-term immediate outcomes, as well as precursors of chronic conditions that may occur later in life.