Care should be taken when antispastic drugs are used in combination with other CNS depressants because drowsiness and sedation may be enhanced. This increases the risk of baclofen toxicity, which presents as confusion, bradycardia, disorientation, and blurred vision. Patients with spasticity may seek the advice of the pharmacist in the treatment of concomitant problems such as constipation. Their condition may also demand the use of an appropriate formulation. For example, a patient with MS living alone may be unable to open blisters.
Pharmacists have a unique contribution to make in the care of patients with spasticity.
They have the potential to improve patients' quality of life. Kirsty Todd is a pharmacist at South Manchester University Hospitals Trust.