To reduce the risk of penile cancer, men are best advised simply to use reasonable hygiene, practice responsible sexual behavior, and to avoid handling tobacco. The history of the penile cancer myth was published by Fleiss and Hodges in the British Medical Journal 30 . Post-circumcision cancer may occur at the circumcision scar. The cause is unknown. One may hypothesize that the circumcision scar tissue is less resistant to penetration of HPV which then transfers DNA to the human cell and starting the growth of the neoplasm.
More research is needed to determine the etiology of post-circumcision cancer.
American Cancer Society. The American Cancer Society issued a five part advisory statement on penile cancer in June 1999. Circumcision is not considered to be beneficial in preventing or reducing the risk of penile cancer . The ACS indentifies HPV, smoking, and phimosis as risk factors. Sexually active adult males with a non-retractable foreskin should have the phimotic condition treated.