In extreme cases, open sores or pus-filled sacks can develop on the genitals. The disease also can erode holes through the vagina or rectum walls. They generally confirm this with a blood test, enabling them to rule-out or check for other STDs, such as herpes, syphilis, chancroid or gonorrhea. A sample of the discharge for a culture test may also be taken. Treatment LGV is persistent.
Penicillins are ineffective, tending to suppress the bacterium without killing it.
Surgery may be needed to repair the scars and erosions, internal as well as external, that result from advanced infection. The only sure way to prevent infection is to limit one's sexual relationship to a single, uninfected partner. Latex condoms are generally effective at preventing infection, if they are put on before sex and worn until the penis is withdrawn. Washing, douching or urinating after sex does not prevent STDs. People with signs or symptoms of LGV are best advised to abstain from sex until the infection is cured.