EMG and nerve conduction tests which exam large fibers only can also be performed. Unfortunately, the diagnosis may still be missed resulting in a misdiagnosis of hysteria or depression. Misdiagnosis of PN can lead to a vicious cycle which includes delay in seeking and procuring proper treatment. Early diagnosis is important, since the less damage that occurs the better the prospects of recovery. Once damage is stopped nerves can regenerate although complete recovery may not always occur.
Orthotic devices can help maintain strength and function.
In my case, wrist and hand splints are helping me type and operate my motorized wheelchair. Controlling pain from neuropathy is not easy. Capsaicin cream, an extract of the pepper plant, is sometimes helpful. The irritation of the pepper acts to deplete the supply of a nerve transmitter known as substance P. Neurontin, a drug originally developed as an anti-seizure medication, has also been used with some success. Topomox, another anti-seizure drug is also being used in some cases.