This research program has been characterizing the structures and functions of a number of ECM molecules and regulatory protein factors. It also studies the intermolecular interactions of ECM molecules.
Members focus particularly on two areas, basement membranes and cartilage.
They study the roles of basement membrane and cartilage components in normal development and disease in animal models. They have also been identifying bioactive sites on laminin. These studies are aimed towards developing reagents useful for diagnostic and therapeutic applications.