Our major research effort is to develop small molecules with neurotrophic action which has therapeutic potential in the treatment of human neurodegenerative disease. Methods used include molecular modelling, peptide synthesis, and neuronal cell culture. The goal is to develop methods of early detection and better treatment for diseases such as stroke, asthma, irritable bowel syndrome, and cystitis. Development of novel pharmacological assays both in vivo and in vitro , and exploratory research projects with opportunities for research training are available. The role of T, L and N-type calcium channels, and agents stimulating angiogenesis and collateral development, are of current interest.
Studies also involve cannabinoid receptors and 'N'-type calcium channels in chronic pain.
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