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Risk is increased if there's a family history of colorectal cancer or polyps.
Early detection can come from a digital rectal exam and fecal occult blood test. There has been some evidence in recent studies to suggest that hormone replacement therapy and taking nonsteroidal anti-inflammatory drugs such as aspirin and ibuprofen may reduce the risk of colorectal cancer. This type of cancer is most common in women over the age of 50. Consequently, it causes more deaths than any other cancer of the female reproductive system. It often produces no symptoms in the early stages, or the symptoms are vague and easily misdiagnosed as gastrointestinal problems.