P stimulates osteogenesis in vitro.
Shih, C . and Bernard, G.W., Calcitonin gene related peptide enhances bone colony development in vitro. Shih, C., Bernard, G.W., Peripheral blood mononuclear cells develop into multi-nucleated osteoclasts in tissue culture. In vitro comparison of aged and young osteogenic and hemopoietic bone marrow stem cells and their derivative colonies. Dr. Bernard's research is involved with embryogenesis and wound healing of bone. He has investigated neuropeptides such as Calcitonin Gene Related Protein alpha, Substance P and the extracellular matrix protein BMP-2 as osteogenic substrates both in vitro and in vivo.