Be sure to take some things that are familiar to your pet, such as a favorite blanket, toy as well as their regular treats to help him be comfortable in unfamiliar surroundings. Ask your vet if they know of a vet in the area you will be traveling. Keep the telephone numbers handy. Never, never, never leave your pet unattended in the car. It takes mere minutes for cars to turn into ovens.
Pets tend to drink more water while traveling, so be sure to have plenty available.
Check pet shops for travel water bowls that have a lid that prevents spilling while moving. Filling said bowl or a small cooler with ice will keep your pet with a steady water supply while the ice melts. Since pets tend to drink more while traveling, it's important to take plenty of litter when traveling with your cat. For familiarity's sake, use the same litter brand as you would at home. Pets tend to shed more when traveling, so it's a good idea to keep a lint brush handy for clothing or car seats.