Chemotherapy followed by surgery followed by adjuvant chemotherapy. Clinical trials are evaluating new methods of giving chemotherapy and new schedules of treatment. The use of radiation therapy is also under study. Chemotherapy followed by surgery to remove the cancer followed by adjuvant chemotherapy. Surgery to remove the cancer followed by adjuvant chemotherapy.
Surgery often includes removal of cancer that has spread to the lungs.
Recurrent osteosarcoma Treatment depends on where the cancer recurred, what kind of treatment was given before, as well as other factors. A clinical trial may be a reasonable treatment option. If the cancer has come back only in the lungs, treatment may be surgery to remove the cancer in the lungs with or without chemotherapy. If the cancer has come back in other places besides the lungs, treatment may be combination chemotherapy. Clinical trials are evaluating new chemotherapy drugs.