Any caseous matter or spongy masses could be a sign of stomatitis and the animal should be taken to a veterinarian for diagnosis and treatment. External parasites such as ticks or mites may plague some specimens, especially imports. Ticks feed off a host be drawing blood and nutrients which would otherwise go towards the growth and repair of the host's cells and body. Carefully remove the ticks by using a pair of sterile tweezers or forceps to gently pull the parasite from the basilisk's body. Betadine solution can be applied to decrease risk of infection.
Some basilisks can also harbor internal parasites such as protozoa and nematodes.
Imports tend to be at greater risk of parasite infestation, but captive specimens exposed to parasites may also become infested. Characterized by loose, runny stools and weight loss, parasitic infestation can be diagnosed via fecal sample examination by a veterinarian and treated accordingly. While basilisks are susceptible to these problems, if treated early they can recover and be enjoyed by the advanced hobbyist. Green and Brown Basilisks especially make beautiful additions to a collection. Trends indicate that captive-bred specimens will continue to be available through private breeders.