Workers are tolerant of cold wet conditions, and may be observed foraging in cloud forest during inclement weather. They forage on the ground and in the canopy. Workers forage in dense columns. Raiding columns repeatedly have been observed attacking Pheidole nests. Colony emigrations are encountered with workers transporting brood and the queen traveling with the column, suggesting nomadic behavior.
Workers have small eyes, reduced to a single facet.
Nest sites are variable and reveal additional similarities to ecitonine behavior. Apparent longer-term nest sites have been observed twice, in extensive chambers in soil. In one of these observations brood were dispersed in various chambers, along with prey remains. It is unknown whether the Simopelta excavated the chambers themselves or occupied preexisting chambers, but the behavior suggests periods of stable use of one nest site, similar to the statary phase seen in Ecitoninae. Males of Simopelta are unknown.