I recall one offer that was never extended to a scientist due to negative comments from a secretary who felt she was snubbed by this fellow. You just never know who will have some sort of impact on the hiring decision. One of the most important pieces of analysis you should consider on interview day is the boss-subordinate relationship. Your new boss will control your destiny. Plan to ask questions about his or her management style.
Most people are happy to talk about their attitudes and philosophy regarding people management.
A recent study concluded that your greatest risk of termination is in the first 18 months of reporting to a new boss. Facts like this only point out how important it is to be able to interview well and probe well at the same time. No matter how they are introduced, assume that everyone you talk with on interview day is going to be involved in the decision to hire. The job market has changed. But, companies are still hiring and positions are out there if you really look for them.