Palms of the hands, and soles of the feet. VesPro Gesterone can be applied to the same capillary beds for as long as needed. The cream is readily absorbed and leaves no trace after a few minutes. During absorption, the progesterone bypasses the liver and goes to specific receptor sites. Everyone is different.
Some women require more progesterone cream to help alleviate symptoms, while others can use less.
For the first 3 months, use one 2 oz. Next try cutting back on the amount of VesPro Gesterone each month until estrogen dominate symptoms occur. Then return to the last dosage used without symptoms. Start applying cream 10 days after first day of your period and stop on day 28. If your period begins before day 28, discontinue use.