Implement barrier isolation to decrease risk of infection. IV antibiotics may be necessary to treat secondary infections. Areas of denuded skin should be managed like thermal burns, although debridement is best avoided while lesions are still progressing. Eroded areas may be bathed q1-2d with saline or Burow solution and dressed with nonadherent dressings. Discontinue use of potentially contributing drugs.
Topical corticosteroids are useful for outpatient treatment of patients with limited disease.
Consider use when recurrences are more frequent than 5 per year. Continue for 6 months. Severe cases of EM major may require treatment in an intensive care unit or burn unit. Transference to such a facility may be necessary. Avoid known or suspected predisposing medications.