This Publication Is Searchable The Merck Manual of Diagnosis and Therapy Section 1. Nutritional Disorders Chapter 3. The first symptoms are anorexia, nausea, and vomiting, followed by polyuria, polydipsia, weakness, nervousness, and pruritus.
Renal function is impaired, as evidenced by low sp gr urine, proteinuria, casts, and azotemia.
Metastatic calcifications may occur, particularly in the kidneys. A history of excessive vitamin D intake is critical for differentiating this condition from all other hypercalcemic states. Williams syndrome consists of transient hypercalcemia in infancy with the triad of supravalvular aortic stenosis, mental retardation, and elfin facies. 2 D 3 during the hypercalcemic phase are 8 to 10 times normal. Most cases are due to an unidentified defect in vitamin D metabolism rather than to excessive intake.