If modifications to a protocol are more than minor, then the proposal has to go back to the full meeting for re-approval. Bad documents often fail to include reasonably foreseeable risks. Documents should minimize the severity or likelihood of risks. Documents often fail to describe research purposes and procedures, and fail to disclose alternative procedures. The protocol should explain the consent process.
Protocols require cursory continuing review.
Marianne sugggests that review and re-approval should take place more frequently than on an annual basis.