Bleeding is mostly internal. The deficiency in clotting factors is associated with a wide range of bleeding episodes, usually into the joints or muscles. Bleeding can be stopped by infusion of the appropriate clotting factor by intravenous injection. If internal bleeding is not quickly stopped with treatment, it will result in pain, swelling and damage to the tissues. Clinical severity within an individual may vary with time.
Severity also varies between individuals with the same level of coagulation factor.
The nature of the disorder can also lead to problems of a social nature.