Growth factor receptors - erbB , receptor for epidermal growth factor c. These genes inhibit excess cell proliferation. Mutation of these genes leads to uncontrolled cell growth. Low level of expression b. Expression restricted to certain times during the cell cycle c.
Some viruses contain v- onc that are constitutively expressed.
C. Cancer Induction Induction of cancer is a multistep process involving loss of anti-oncogenes and activation of oncogenes. I is associated with poor prognosis. IL2 for activation than LAK cells. See Table 25-6 a. TIL cells producing high levels of TNF- are grown in culture and infused back into patient.