The type and amount of extractables will vary with the type of liquid being filtered. Extractable components that can end up as contaminants may be minimized with sufficient preflushing. Top Binding Binding is the property of substances to have affinity for filter media or other filter components. Binding can be a desirable characteristic, as in the case of nucleic acid or protein binding on certain microporous transfer membranes, or an undesirable characteristic, as in the case of protein binding during filtration of proteinaceous solutions, sometimes leading to a loss of active ingredients during filtration. Top Thermal Stability Thermal Stability is the ability of the filter media and device components to maintain integrity and functionality at elevated temperatures.
Stability is measured by determining the maximum operating temperature under specified conditions.
Thermal stability is important when considering filter or device sterilization, such as autoclaving. Certain filtration media and devices are not autoclavable due to insufficient thermal stability. Top Flow Rate and Throughput Flow rate and throughput are two important related measures of filter media and device performance. This performance is affected by many different variables. As the filter begins to clog, upstream pressure increases and differential pressure increases.