They will return to normal 2-3 weeks after your last dose. Platelets help to make your blood clot when you hurt yourself. You may bruise or bleed more easily than usual. Clean your nose by blowing gently, do not pick your nose. Sore mouth may occur a few days after you start taking methotrexate.
Mouth sores can occur on the tongue, the sides of the mouth or in the throat.
Mouth sores or bleeding gums can lead to an infection. Stop taking methothrexate and call your cancer doctor for advice. Brush your teeth gently after eating and at bedtime with a very soft toothbrush. If your gums bleed, use gauze or your finger instead of a brush. Make a mouthwash with teaspoon baking soda or salt in 1 cup warm water and rinse several times a day.