Some have defined functions while for others no definitive function has been established. Some also have androgenic activity. The glucocorticoids have great pharmacologic value in their anti-inflammatory and immunosuppressive activities. Topical Steroids Topical steroids are anti-inflammatory drugs that are applied directly to a specific area of the skin . They are used to treat many inflammatory skin diseases, and are available in a variety of forms, such as lotions, creams, ointments, nasal sprays, or solutions.
Topical steroids suppress the inflammatory response.
This is due to the thickness of the skin in that area. However, absorption is increased where natural barriers have been decreased or destroyed. For example, absorption of topical steroids increases where the skin is inflamed at wound sites, and in other areas where the skin is not intact or is thin. The majority of these drugs have similar side effects, including dry, irritated skin, and unusual growth of hair on the face or body after prolonged use. Others may have additional side effects.