This should be taken with meals, and those taking it should avoid foods and medications that are known to interact negatively with MAO inhibiting drugs. Never mix St. John's wort with prescription anti-depressants, and consult your physician before changing treatments you may already be on. St. John's wort may also cause photosensitivity in certain individuals at high doses. Then I add it to the hot water, stir, then add one tsp. It is important to remember that the effectiveness of herbs is directly related to personal sleep habits, nutrition, and exercise.
Many herbs take a while to get into the system before they start to work.
St. John's wort in particular, may require as long as 3 months of regular usage before benefits may be seen. The way I see it, it took a long time for my body to get in the shape it's in now, and it's certainly worth a bit of patience on my part, knowing that this time I am being healed the way my body was designed, and with God's own medicine. I cannot stress enough the importance of knowing what goes on with, and into our bodies. Herbs were put here by God for us to use as food and medicine, but when used incorrectly can be just as harmful as anything else on this planet. This is the regimen that I currently use, the basis of which I credit for helping me avoid the the liver transplant that my doctor believed I'd need within a year- back in 1994.