Summary he purpose of this study is to evaluate the efficacy of parecoxib in patients undergoing unilateral total hip arthroplasty under spinal anesthesia. Parecoxib, a cox-2 inhibitor, is used to treat moderate to severe pain. Either the study drug, Parecoxib IV, or a placebo will be given to the patients approximately 30-45 minutes before the operation. The patient will then be asked to assess their level of comfort beginning two hours after the operation.
Patients can ask for rescue medication at any time.
The patient participation will being 30-45 minutes before surgery. Patients will complete the study 24 hours after surgery has been completed. The study will be conducted at several centers throughout the United States. All Rights Reserved. Contact the Web Development Office .