Review of epidemiological studies on cancer showing protection by consumption of fruits and vegetables.
Mutations also accumulate with age.
DNA is oxidized in normal metabolism because antioxidant defenses, though numerous, are not perfect. As the link between diet and overall health continues to gain attention, public awareness of the benefits of fruits and vegetables has expanded. Strict vegetarians are at increased risk of developing a Vitamin B12 deficiency, which is also common in the elderly. Niacin contributes to the repair of DNA strand breaks by maintaining nicotinamide adenine dinucleotide levels, which are required for the poly ADP-ribose protective response to DNA damage. Optimizing micronutrient intake can therefore have a major impact on health.