Another rare, but notable adverse reaction is the formation of certain anti-bodies, including the antinuclear antibody. Other side effects include headache, runny nose and nausea. Enbrel is relatively new to the scene so long term effects are not yet known. It has not been studied in pregnancy or nursing mothers and should not be used unless absolutely necessary. Arava is taken by mouth, usually 100mgs a day for three days as a loading dose, then 20mg per day thereafter.
Most people begin to notice an improvement in as little as a month.
Arava works by inhibiting certain enzymes, dihydroorotate dehydrogenase, and has an anti inflammatory response as well. Like MTX, Arava's side effects can include liver problems, GI disturbances, and hair loss. Blood tests to monitor liver function should be done at least monthly in the beginning and then at the discretion of your doctor. Because of the risk of liver damage, Arava should not be taken by those with pre existing liver problems. Arava should never be taken during pregnancy and should be avoided by both partners prior to conception.