The remainder showed supra-normal tracer uptake. Bone scanning can be helpful in conjunction with radiography to detect polyostotic involvement. Intense uptake of gallium is seen in the dysplastic bone. No preferential uptake of thallium or indium-labeled leukocytes is seen. A variable clinical course is seen.
Patients are often asymptomatic.
Others experience pain, pathologic fractures and bone deformity. Craniofacial fibrous dysplasias can result in impingement of the cranial nerves. An increased incidence of sarcomas is seen in dysplastic lesions, unattributable to prior radiation therapy. Associated symptoms include pain and swelling. Clinical mimics of sarcomatous degeneration are the coexistence of a secondary aneurysmal bone cyst and cystic degeneration of fibrous dysplasia.