Food neutralises the acid. This secretion is also stimulated by vegas nerve. Whenever we feel hungry, see or smell food, or we become anxious or angry, impulses transmitted by this nerve stimulate stomach secretion. It is secreted through out the day. In absence of food this excess secretion may work on stomach and duodenal mucosa and digest it and form peptic ulcer.
Peptic ulcer is a chronic condition.
Spontaneous relapse and remission of ulcer last for decades. Recurrent abdominal pain. Epigastric pain - Pain is referred to the epigastrium and is sharply localised. Hunger pain - Pain occurs when the stomach is empty and relieved by eating. Night pain - Pain wakes the patient from sleep and may then be relieved by food, drink, milk or antacid.