In Vitro Epidemiology Alternative Methods 1. Most drug approval cannot take place without in vivo testing 1. Allows quick testing of new products using human cells and is generally less expensive. Large human populations can be studied over an extended period of time. Models can be made from existing data that combine all types or combinations of the various toxicity tests.
Most mammals share a common organ structure that permits extrapolation from one species to another.
Improves the capacity to test most pure chemicals or combinations of substances. Usually admissible as evidence. Computer simulations can solve the differential equations relating in vitro tests to in vivo results. Permits experimentation on live models in a controlled environment. Most in vitro tests are relatively simple with easily quantifiable results.