Read Salyers, Chapter 8. The global problem of infectious diseases 1. The appearance of new and potentially dangerous infections. There now exists strains of bacterial pathogens resistant to all known antibiotics. Here lies the essence and challenge of bacterial pathogenesis.
True understanding requires an appreciation of a wide variety of methods and systems.
We will focus on model bacterial systems for much of this class. The field has been recently named cellular microbiology . Leads to studies of evolution of disease, minimal genome, etc. Also of note, it that the sequence of the mouse genome will be completed soon. Disease is a state where damage has occurred to the host.