The Toxins Group Bacterial toxins cause many important diseases, but conversely are useful components of vaccines.
Toxins are also potent tools in eukaryotic cell biology.
The UMDS toxins group is interested in a new group of toxins that directly affect the regulation of cell growth, and also the modelling of bone. The group is funded by the Wellcome Trust and the Biotechnology and Biological Sciences Research Council. Pasteurella multocida toxin, a potent intracellularly acting mitogen, induces p125 FAK and paxillin tyrosine phosphorylation, actin stress fiber formation and focal contact assembly in Swiss 3T3 cells. Pasteurella multocida toxin is a mitogen for bone cells in primary culture. Constitutive expression of the Pasteurella multocida toxin.