In my own clinical experience, I get better results mixing it. I asked Dr. Kronberg about this. Of course, it will be the transplant. Heredity, disease, stress, and various drugs can cause thinning of hair. Diagnosing such hair loss often requires considerable sleuthing.
Pregnancy can also cause hair thinning.
Hashimoto thyroiditis, an inflammatory disease of the thyroid, can cause thinning that resembles male pattern baldness. You have to specifically look for antibodies. If you just do a thyroid screening, you won't pick it up until the thyroid is burned out. That can cause hair loss over a period of years. Many surgeons and clinics claim to provide a new hair-transplantation method of their own invention, but there is nothing new in this field except improved technology.