There is a chapter on Photoshop Techniques that will guide you through a myriad of Photoshop attributes. I will not labor on them here, but suffice it to say there is an explanation of such techniques as using the layers palette, transparency, using Illustrator, removing dust and scratches and noise, etc. Not only does this book explain the nuances between these choices, but also explains in what circumstance you would want to use one over the other. In addition, the author provides detailed graphs showing the significance of saving one version over the other on various graphic types. You can then not only see the results on the image, but on the resulting size of the image's file.
Most people are aware that using blurring can improve compression.
Unfortunately, the appearance of a Gaussian Blur can be detrimental to the image's quality. A Smart Blur, however, can decrease the size of the image and not damage the sharpness of the image. There are two chapters devoted to ImageReady, mostly focusing on how to perform slices, rollovers, and animated GIFs. Likewise, there is a chapter on GoLive covering a wide amount of techniques, few of which deal with graphics. Rather, there is information on backgrounds with tables and grids and aligning Foregrounds with the backgrounds, working with text, CSS, external CSS, Dynamic fonts, and stationary and components.