RfDs can also be derived for the noncarcinogenic health effects of substances that are also carcinogens. Therefore, it is essential to refer to other sources of information concerning the carcinogenicity of this substance. If the U.S. EPA has evaluated this substance for potential human carcinogenicity, a summary of that evaluation will be contained in Section II of this file. 90-day Rat Report. Unpublished study performed by Southern Research Institute.
Mice appear to be more resistant than rats to the effects of orally administered furfural.
A 13-week study reported by Feron et al. In addition, chronic toxicity and developmental and reproductive toxicity of furfural have not been adequately investigated. A low confidence in the RfD reflects a low level of confidence in the study and the data base. In addition no studies supporting the RfD were available in the literature. Furthermore, the developmental and reproductive toxicity of furfural have not been adequately investigated.