A job search is a job in and of itself. Leaving it until the last minute will only make matters worse. If you are targeting start-up companies, be prepared to be the driver. As opposed to large corporations, smaller firms will not have elaborate training and recruiting programs designed. The smaller the firm, the more they will rely on you to let them know what you can do for them, rather than the other way around.
Professional persistence is required to secure a position with a start-up.
The informational, or networking, interview is an effective method of developing contacts, broadening your knowledge of an industry, and garnering position leads. Recognize, however, that informational interviews are not a quick way to find a job patience and persistence are key. Cultivating a relationship can take several interactions within a framework of no set deadlines. Be honest and professional in your approach. In most cases, people are looking for leads on jobs, career advice or industry information that will help them later in their job search.