Click to see large image. The nigrostriatal dopaminergic system with cell bodies located in the substantia nigra. Projections are to the putamen and caudate. Click to see large image. The tuberoinfundibular dopaminergic system with cell bodies located in the arcuate nucleus of the hypothalamus.
Projections are to the pituitary stalk.
Comprehension of the dopaminergic hypothesis of schizophrenia also requires knowledge of dopaminergic transmission. Guidance in arriving at an understanding of these concepts is also provided below. The potential sites of drug action are shown in Figure 6. Essential elements of dopaminergic transmission. Potential sites of drug action on dopaminergic terminals and postsynaptic membranes.