Pepsin is an enzyme that controls the hydrolysis of proteins into peptides. The stomach also mechanically churns the food. Chyme, the mix of acid and food in the stomach, leaves the stomach and enters the small intestine. Scanning electron micrograph of the stomach lining of a mammal, X2000. Pepsinogen is an enzyme that starts protein digestion.
Pepsinogen is produced in cells that line the gastric pits .
It is activated by cleaving off a portion of the molecule, producing the enzyme pepsin that splits off fragments of peptides from a protein molecule during digestion in the stomach. Carbohydrate digestion, begun by salivary amylase in the mouth, continues in the bolus as it passes to the stomach. The bolus is broken down into acid chyme in the lower third of the stomach, allowing the stomach's acidity to inhibit further carbohydrate breakdown. Protein digestion by pepsin begins. Alcohol and aspirin are absorbed through the stomach lining into the blood.