This material is highly nutritious for larvae developing in the environment but if this flea dirt is packed with lufenuron, the larvae will not be able to grow normal exoskeletons and they will die. The injectable formula for cats was designed as an alternative to the relatively unpopular oral liquid. Like the oral product, injectable Program is stored in body fat. One injection is effective for six months. Since Program works on enzymes systems which are unique to insects, no other side effects have been reported even in animals fed hundreds of times the recommended dose.
Program is therefore compatible with all other treatments.
It is important to note that with the advent of popular topspot treatments for fleas, special attention should be paid to the development of resistance to these products. Experience with other insects tells us that resistance can develop in 12-15 generations. In order to preserve these new insecticides, it is important to consider what is called integrated pest management. What this means is that insecticides should be rotated or combined with insect development inhibitors such as lufenuron or insect growth regulators like methoprene. Fleas that are resistant to the topspot treatments must not be allowed to pass on their genes for resistance.