It may take some adjustments to find the best amount or right drug for you. High blood pressure drugs work in various ways. Often, two or more drugs work better than one drug. This reduces the amount of fluid in the blood. And since sodium is flushed out of blood vessel walls, the vessels open wider.
Pressure goes down.
There are different types of diuretics. They are often used with other high blood pressure drugs. Blood pressure drops and the heart works less hard. They shield blood vessels from a hormone called angiotensin II, which normally causes vessels to narrow. As a result, the vessels are wider and pressure is lower.