In puppies, it can contribute to severe disease when combined with other intestinal infections, leading to diarrhea , dehydration and possibly death. It is characterized by diarrhea , fever, seizures, skin lesions, lethargy and watery discharge from the eyes and nose.
Parvovirus normally infects the dog's intestines, lymphoid tissue and bone marrow.
The result is vomiting , diarrhea and severe dehydration. Signs of infection include a dry, hacking cough or coughing spasms followed by retching or gagging. Toy breeds and geriatric dogs are at especially high risk for chronic respiratory disease. Most adult dogs can recover from hepatitis, but puppies often can't. Adenovirus type-1 can cause fever, diarrhea and severe liver, kidney and eye damage.