They also work together to help prevent the formation of new lesions. Vitamin A was effective in the treatment of some premalignant and malignant skin conditions. The current consensus is that it probably does not cure skin cancer, but treatment may prevent the formation of new lesions as long as therapy is continued. This was true for a variety of skin cancers ranging from malignant basal cell carcinomas to premalignant actinic keratoses lesions when treated with oral retinoids. In addition, an increase in dietary vitamin C has been shown to reduce UV-induced tumors in mice.
Wound healing is an important indicator of skin health.
To enhance wound healing, it is important that patients receive adequate amounts of each vitamin. A deficient experience diminished wound healing, which is correctable by vitamin A supplementation. Vitamin C is considered critical in wound healing because it acts as a cofactor for several enzymes, which stabilize collagen. Through its antioxidant and anti-inflammatory effects, topical vitamin E may enhance would healing, although the benefits remain controversial. More research is needed to determine if and how vitamin E supports the wound healing process.