Cost is a crucial issue. Users' views are important. Validity of dropout rates as proxy measure of tolerability is unknown. Paper corrupts concept of evidence based medicine. Full-text article LEE S. Atypical antipsychotics in the treatment of schizophrenia.
Pragmatic considerations are important when considering which drug to prescribe.
Paper underrates patients' experience of extrapyramidal symptoms. Randomised trial of personalised computer based information for patients with schizophrenia. Wilson S. Using patient identifiable data without consent. Argument for consent may invalidate research and stigmatise some patients. People with comorbidity can fall between two stools.