This leads to symptoms such as perosis in chicks and crooked calf. The latter are usually associated with the ingestion of range lupine by cows. Lupine contains substance interfere with Mn absorption. Mn metabolism is very similar to Fe metabolism. It should not be a surprise to you that excessive Mn in diet can induce Fe deficiency.
Selenium is a component of glutathione peroxidase, an enzyme for removal of lipid peroxides.
Se is also a component of two other selenoproteins. Midpiece of sperm requires selenoprotein. Microbes in the rumen replace S with Se in their S-containing amino acid synthesis. They are absorbed in duodenum as amino acids. White muscle disease, exudative diathesis are two Se deficiency symptoms, which can be treated with both vitamin E and Se.