Go one block on Byberry to the next light, then follow above from the asterisk. The Marriott's web site has maps available. The map page has a detail of center city showing the Marriott and some landmarks on the street map. Driving instructions are also available through this page. Numerous parking lots line the adjacent streets, including a lot immediately across from the Marriott.
Valet parking is available as well.
The page has more directions, although not to our specific building. A map of the campus is also available. Follow that street until you get to Cooper Street. Turn right onto Cooper and go to 3rd Street. Make a left onto 7th, which is the bridge over Rte.