Chemotherapy is the most important measure in treatment of this disease. Surgery and removal of the uterus is indicated when there is no desire for having any more children. Surgery will shorten the duration and amount of chemotherapy. Dose and intensity of treatment is determined by the extent of the disease and the risk levels High-risk patients are treated much more aggressively. Serial blood tests must be performed during and following the completion of treatments, to assure normalization the hCG levels.
Radiation therapy is used for treatment of brain metastasis.
Contraception should be maintained during and for one year following chemotherapy. Because these patients are at increased risk of recurrence, they should e monitored with Pelvic Ultrasound during their future pregnancies.