Use the same keywords in both the META tags and the body of your document. This will help prevent search engines from interpreting your site as spamming certain keywords. Many search engines won't follow refresh tags to load the next document. If your site uses a splash page that opens the main home page, submit your main home page instead of the splash page. Shuffle the sequence of META tag keywords across different pages and in ALT tags.
Some search engines implement spam-detection software that works by looking for long string matches.
Avoid words used by adult sites or spam sites. Consider every page on your site as a potential entry point. Search engines constantly change their indexing algorithms, which can cause pages you never thought to be important to suddenly show up in the listings. Include navigation links on every page so that visitors can quickly find the rest of your site. Use questions in your documents.