Attenuated androgens such as danazol and stanozol are effective and relatively safe and can be used for long term control. Papular Urticaria Index Papular urticaria is a term used to describe crops of grouped, itchy, erythematous papules or small blisters. The pathogenesis is unknown but it is known to be caused by insect bites. The usual offending insects are fleas or mites on domestic cat and dogs, but the human flea, bedbug mosquito and dog louse are sometimes incriminated. Worldwide fleas and bedbugs are the most common causes.
Papular urticaria is rare in the first year of life.
It afflicts predominantly children between the ages of 2 and 7 years, but may occur in adults. The incidence decreases with age, presumably due to specific hyposensitization by repeated bites. The condition is frequently seasonal, especially in temperate climates where they are worst in the summer. It may also be perennial. The eruption consists of wheals or firm papules, or of wheals surmounted by papules.