Impaired capacity to lose visceral adipose tissue during weight reduction in obese postmenopausal women with the Trp64Arg beta3- adrenoceptor gene variant. Effect of dietary energy restriction on glucose production and substrate utilization in type 2 diabetes. Obesity induced by a high-fat diet is associated with reduced brain insulin transport in dogs. Plasminogen activator inhibitor 1, transforming growth factor-beta1, and BMI are closely associated in human adipose tissue during morbid obesity. Involvement of protein kinase C in human skeletal muscle insulin resistance and obesity.
Obesity is associated with a decreased leptin transport across the blood-brain barrier in rats.
Divergent regulation of Akt1 and Akt2 isoforms in insulin target tissues of obese Zucker rats. Differential brain responses to satiation in obese and lean men. Effects of troglitazone on blood concentrations of plasminogen activator inhibitor 1 in patients with type 2 diabetes and in lean and obese normal subjects. Abstract Related articles SHAO J, Catalano PM, Yamashita H, et al. Prolonged elevation of plasma free fatty acids impairs pancreatic beta- cell function in obese nondiabetic humans but not in individuals with type 2 diabetes.