The voice or cry is often described as high-pitched and soft, hoarse or squeaky. Feeding difficulties are usually present, e.g., poor appetite, chronic vomiting. Recurrent infections are common and usually involve the ears, urinary tract, and upper respiratory tract. Cleft uvula, which is a separation in the projection that hangs from the palate in the back of the mouth, is occasionally present. Club foot, flat feet, or feet that are outwardly angled are seen.
Various allergies are common.