Each 70-mer probe is optimized by selecting regions with maximal specificity relative to all other malaria genes, biased towards the 3' end of the ORF, and melting temperature normalized. The P. falciparum genome set will allow researchers access to much-needed data about the world's most widespread tropical parasitic disease. Worldwide prevalence of the disease is estimated to be 300 to 500 million clinical cases each year, and increasing drug resistance is a major obstacle to effective treatment. Download a detailed description of this oligo set. The UniGene database automatically clusters all human Genbank sequences into a non-redundant set of genes.
Similar databases are also available for the rat and mouse genomes.
Each cluster in the UniGene database represents one unique gene. A cluster may contain many sequences, but one representative sequence has been selected based on the longest region of high-quality sequence data. The set also contains 29 controls. As more known genes become available in further releases of UniGene, additional oligo sets will become available for purchase. Download a detailed description of this oligo set.