Alkylating agents damage the programs that control growth in the chromosomes of the tumour cells.
Natural products interfere with cell structure and cell division.
Hormones block the effect of oestrogen by acting on the oestrogen-receptors. Bleomycin Fever, skin reactions, nail ridging, pulmonary changes. Carboplatin Nausea, vomiting, bone-marrow suppression, nephrotoxicity, diarrhoea. Cisplatin Nausea, vomiting, diarrhoea, bone-marrow suppression, renal toxicity, neurotoxicity. Cyclophosphamide Bone-marrow suppression, hair loss, nausea, vomiting, cystitis, haematuria.