Yes, it is remote yet easily accessible. The town is under native rule and dry by law. Remember to bring any alcoholic beverages you may desire. Iliamna is located about 200 miles southwest of Anchorage and about an hour flight. There are many lodges in this area with each offering something a little different.
Some lodges lease parts of or entire streams for private and unbelievable fishing.
Make sure the lodge has a catch and release only policy on rainbows. A lodge that is able to take one to a variety of streams will have float planes and jet boats for best accessibility to prime spots. Float trips are a fantastic way to fish these streams and may be something to look for. Your lodge should have backup fishing trips in case the weather does not permit flying. The Complete Guide by Rene Limeres and Gunnar Pedersen.