Because of the effects of the drug they forget how much they have taken. A major problem with depressants is the availability of these drugs through a written prescription. A major problem with depressants is the availability of these drugs through a written prescription. The safe range of depressants is very narrow. The effects of barbiturates are similar to the effects of alcohol.
Small amounts produce calmness and relax muscles.
Somewhat larger doses can cause slurred speech, staggering gait, poor judgment, and slow, uncertain reflexes. These effects make it dangerous to drive a car or operate machinery. Large doses can cause unconsciousness and death.