Always remember that tarantula species differ in their temperaments, and some species are more defensive than others. No live tarantula of any kind can be guaranteed not to bite. Several tarantula species can kick defensive hairs off the top of the abdomen. If you are sensitive to these hairs, you will usually feel a slight itching. It is always a good idea to rinse your hands and arms after handling your tarantula, and to not rub your eyes until you ve done so.
Some species cause more itching than others, and individual reactions vary from person to person.
Like all other arthropods, tarantulas molt their exoskeleton periodically. The tarantula generally stops feeding for a week or more, and then usually turns over on its back. The old exoskeleton splits, and the spider works it off and then flips upright. Finally, the new exoskeleton enlarges and hardens. It will be several days before this last part is complete, and the spider does not eat, nor should it be handled, during this time.