Our group is mainly involved in research and development of new methods for sequence analysis and applying them to genomics research. These include automated and graphical tools for homology analysis, methods for analyzing protein domain families, and methods for predicting and visualizing sequence features. Some of the main projects are outlined below. However, it is possible to detect more distant relationships by comparing a sequence to features that are conserved within a protein family. A multiple alignment viewer Belvu was developed to facilitate the analysis of protein domain families.
Predictions are always subject to errors.
The best analysis is often achieved by integrating the output of several prediction methods or parameter choices into a graphical view. This allows a human expert to judge the relevance of the different pieces of evidence. A general system for displaying different types sequence features is under development. A prototype can be tested here . A system for easy extraction of orthologous relationships between two genomes is under development.