The conveyance and processing of pharmaceutical materials is significantly influenced by such factors as crystal habit, surface and mechanical properties. In partnership with Professor J.N. Sherwood, fundamental studies of the crystal growth of materials such as paracetamol are being carried out in relation to growth conditions. Growth mechanisms directly influence morphology and the surface properties of individual crystals, so a more basic understanding is of crucial importance. Microindentation techniques are also being employed to identify the mechanisms involved in deformation. Work on aspects of the crystal growth of racemic and single enantiomer ibuprofen has highlighted the role of solvent in crystallisation.
Research is still ongoing to provide a more detailed understanding of the mechanisms involved.
National meeting, Chicago,1990.