Phase II study of irinotecan as first-line chemotherapy for patients with advanced colorectal carcinoma. Cell differentiation and chemotherapy influence p53 and Mdm2 immunoreactivity in human HT29 colon cancer cells grown in scid mice. Aberrant activation of c-kit protects colon carcinoma cells against apoptosis and enhances their invasive potential. High cancer cell death in syngeneic tumors developed in host mice deficient for the stromelysin-3 matrix metalloproteinase. Human papillomavirus 16 and 18 L1 serology compared across anogenital cancer sites.
Pouch adenomas after ileal pouch-anal anastomosis for familial adenomatous polyposis.
Harmonic scalpel in laparoscopic colorectal surgery. Adenomatous polyps develop commonly in the ileal pouch of patients with familial adenomatous polyposis. Integrating the oral fluoropyrimidines into the management of advanced colorectal cancer. Family history as a risk factor for colorectal cancer in inflammatory bowel disease. Backwash ileitis is strongly associated with colorectal carcinoma in ulcerative colitis.