A specially shaped collection channel around the outer perimeter of the Rotor collects the eluting mobile phase. The entire collection vessel is angled so that gravity drains the eluent to the exit port where it can be collected. The design of the vessel preserves the integrity of the sample bands so as to prevent remixing of the sample component bands. The CycloGraph centrifugal chromatography system combines the advantages of both preparative TLC and Column Chromatography. It delivers fast, efficient separations.
Most separations occur in twenty minutes or less.
Fast separations are a result of the centrifugal action of the spinning Rotor driving the mobile phase through the adsorbent layer. The velocity of the mobile phase enables the use of smaller particle adsorbents. This smaller particle bed versus the 35-75 micron cut typical of low pressure column chromatography allows a higher degree of separation efficiency. Centrifugal action combined with the use of a solvent pump to apply the mobile phase allow complete control of solvent velocity profile. Tight bands mean eluted fractions can be collected in a minimum volume of solvent.