Break the dominance of the car and think of the project as a compound of structures, each with indoor and outdoor living spaces. An ideal location for a house is partway up the slope of rolling land, open to the south, partially protected on the east and west, and sheltered from the north. Homes have always been built in such transition zones. Build on dry, well-drained soil with no history of flooding or instability. Don't build too close to the road.
Money spent on a longer drive is a good investment in privacy and leads to higher resale value.
Build a curve into the entry drive even if a straight one would be shorter. This will give variety to the entry process, increase privacy and make the property feel larger. On a non-view site, clearing to the south of the house will bring in the sun. Your large window areas can then face this south view and focus on the landscaping and activities of this outdoor area.