You need 75 mg to 100 mg of carbidopa to inhibit the full daily supply of dopamine decarboxylase. There s not enough carbidopa in that tablet. So low dose Sinemet is somewhere between 100 and 500 mg a day. Medium dose is between 600 and 1,000 and high dose is anywhere from Sinemet. A combination of carbidopa and levodopa.
Onset of action is in a half hour.
The peak effect is in two hours and the duration of effect is three to four. It s pretty convenient to dose this three times a day, four times a day. It competes with dietary amino acids for absorption. And then Side effects. You invariably have to keep increasing peoples Sinemet.