1,2 septicemia due to line infection, tissue damage from extravasation, etc. Oral medications are less expensive than intravenous medications and have fewer hidden costs.
Oral medications require less nursing and pharmacy preparation and administration time.
Converting to an oral medication earlier in therapy may decrease the patient's length of stay. The patient's condition is improving as indicated from clinical findings. Patient is on a protocol or study which specifies the IV form of the medication. Patient has uncontrolled nausea or vomiting. Administration of oral meds by established feeding tube is not possible or advisable.