All participants will be given a total of 7 treatments over 30 months and followed for an additional 6 months after the last treatment. You must be willing to practice safe sex during the study period. You cannot be an IV or injection drug user. The NCI will pay for airfare for every visit except the first. This trial will study two peptide vaccines for the treatment of HIV infection.
Peptide vaccines contain fragments of genes that can prompt an immune response.
Participants will be divided into three groups. Participants must have been on highly active antiretroviral therapy for at least 4 weeks. The study lasts 15 months during which time participants will be given a total of 6 vaccinations and monitored for two hours after each one. Check with study coordinator about T4 count history. Total time on treatment is one year.