In the treatment of diaper area hemangiomas early aggressive laser can eliminate the need for steroid use. Many parents would rather not treat with steroid because of the side effects. Evaluation by a physician experienced with hemangioma management or a multidisciplinary team is recommended. Some physicians prefer interlesional injection of steroid to the oral use. This technique works well in localized and small lesions.
Recent reports show no advantage of injection over oral use.
Injection in the diaper area is not the treatment of choice. Injections are extremely painful and require sedation. Injection does not reduce the side effects. A second pharmacological treatment of hemangioma is interferon. Alpha 2a interferon is an antiviral drug developed in the research of cancer treatments.