Vitamin A deficiency predisposes to serious disease. Therefore pneumonia more common in developing countries - most common cause of death. Otitis media Enteritis - inportant cause of death and morbidity in developing countries. Live attenuated virus has been used 1968. In addition, some sporadic cases of measles may have occurred in persons who were not protected by the vaccine.
Rubella can cause congenital fetal defects if it infects pregnant women.
Live attenuated virus has been in use since 1969. Complications mostly in young females with transitory arthritis. Infections by these viruses are not distinctive clinically except for Hand-Foot and Mouth disease due to Coxsackie A16. This occurs in young children and is characterized by fever with vesicles in oral cavity. The rash may be accompanied by a mild febrile illness.