Patients suffer from high blood pressure. The growth of all extremities after adult age causes also the vertebrae to extend and the spine to curve. This extension can cause pain as the nerves suffer pressure. Especially typical is the enlargement of the fingers and the dough like feeling of the palms when shaking hands. Psychologically patients suffer initially from depression, brooding and irritability, also an increase of appetite and a loss of libido.
Some patients are anxious and are lacking in self-confidence.
When the adenoma exerts pressure on the third ventricle and the optic chiasma in the brain the patients may suffer from hallucinoses. Uniformly these patients are trustworthy. Their personality is characterised by conscientiousness, reliability and industriousness. Confronting this picture of the symptomatology of acromegaly with the tradition about Muhammad one can only state the conformity. Moreover one understands some other traits of the personality of Muhammad.