It is advisable that the intraocular pressure be checked frequently. In those diseases causing thinning of the cornea, perforation has been known to have occurred with the use of topical steroids. If infections which are present before use do not respond promptly, the preparation should be discontinued until the infection has been adequately controlled by other measures. If new infections due to bacteria or fungi appear during therapy, appropriate measures should be taken. If sensitivity or irritation develops, discontinue use.
More prolonged treatment is permissible in patients showing progressive improvement.
If the response is inadequate, it is undesirable to persist with medical treatment to a point where surgical measures are unduly delayed. Depending upon the condition, 0.25 to 1 mg may be given 3 or 4 times daily.