Depressive illness or clinical depression, can affect anyone, at any age.
Women report depression twice as often as men.
Hormones are definitely involved, as they affect neurotransmitters. Many famous, very successful women have suffered from depression. Queen Elizabeth was depressed and so was Barbara Streisand. Both Abraham Lincoln and Winston Churchill suffered from periods of depression. As many as one in five Americans will suffer at least one episode of serious depressive illness during their lifetimes.