The anwser is in the opposite direction than one might think. E ven suicide cannot kill our eternal spirit - each of us are stuck with ourselves, for ever. But we can kill the negative in ourselves. And not by some long course in Eastern meditation or Western psychiatry. Not through the bottle or needle.
Self is still there at the end of all that.
The Bible makes it clear. Jesus, the son of God, was without fault. He died for us, taking on our faults and weaknesses, every one. If we have been united with him in a death like his, we will also be united with him in a resurrection like his. Death has no authority over Jesus.