Alcohol has long been associated with cancers of the mouth, pharynx, larynx, and esophagus, and there may be a link with liver and breast cancer. Chewing tobacco and snuff can cause cancer wherever they contact the mouth or nose. It pointed out that benefits can outweigh the risks. Tamoxifen, made under the name Nolvadex by AstraZeneca, can increase the risk of endometrial, or uterine, cancer. But endometrial cancer is so rare that doctors say the higher risk is small.
Tamoxifen is the first drug to be shown to prevent breast cancer in some women at high risk.