Metabolic Therapy has been proved to be a very safe procedure. Amino acids are already in our body. The pool of free amino acids is between 100 and 200 grams in an adult, a 14-kg child about 50 grams. So when we introduce additional amino acids they are not foreign to our bodies, we just change the pool of free amino acids by a few percent. - Secondly . Potentially any chemical substance, which is taken, can be dangerous.
Safety depends on a dose within the therapeutic range.
Therapeutic range is the difference between the dose we use for treatment and a higher dose, which could result in an adverse effect. The distance between these two levers is wider than less risk of the drug application and vice versa. For some drugs the therapeutic range can be several milligrams. The therapeutic range of amino acids is extremely wide. For amino acids adverse effect was established only on animal models which was equal to a very high dose intake for humans over a long time period of time.