Yeast provides a useful system for drug testing in several ways.
First, their use for growth-based assays for various chemical screens, second as model organisms for investigation of complex eukaryotic cellular processes, and third their use as a recombinant system for analysis and validation of therapeutic target proteins from higher eukaryotes. We envisage a four-pronged approach combining genetic, molecular biology, biochemical and electrophysiological technologies in order to develop the system.