MPS VI, or Maroteauz-Lamy syndrome, resembles Hurler syndrome. Onset is in infancy, however, intelligence is normal. Individuals may live into the second or third decade. Individuals with MPS VII, Sly disease, experience corneal clouding, skeletal irregularities, and enlargement of the liver and spleen. There is no cure for the mucopolysaccharidoses.
Treatment is symptomatic and supportive.
In several individuals, bone marrow transplants have been attempted with varying degrees of success. The prognosis for individuals with mucopolysaccharidoses varies depending on the type. Because the genes for several forms of the mucopolysaccharidoses have been found, scientists are hopeful that understanding the genetics of the disorders may lead to breakthroughs in treatment. This fact sheet is in the public domain. You may copy it.