Many people also experience a mild loss of sensation in the limbs, fingers and toes.
Although initially felt to be one disorder, there are now thought to be numerous types of this disease that differ in clinical severity, genetic patterns of inheritance and changes noted in nerve biopsies. This type is also known as the hypertrophic type. This degeneration of the insulating material gives rise to very slow conduction impulses in the nerves. HMSN Type II, is also known as the neuronal form. There is a comparatively greater loss of muscle bulk below the knee.