Lymphocytes are made up of two major types of cells, T cells and B cells. Each is responsible for recognition of specific antigens. Phagocytes include neutrophils, eosinophils and mononuclear phagocytes. The macrophage or big eater is the most known of all the phagocytes. Imagine the macrophage as the Pac Man of our immune army.
Phagocytes initiate our nonspecific immune response.
This nonspecific response is incredibly important to our first line of internal defense from foreign substances like viruses, bacteria fungi and cancer. There is considerable interaction between phagocytes and lymphocytes. Of all the cells mentioned, the macrophage is the most ubiquitous or ever present. For example, macrophages exist in all tissues, organs, blood, and lymph. If the appropriate response is not clear, they attack and internalize or eat the entity.