Adults may produce several broods. Scorpions use the pincers to capture and hold prey. This species occurs under rocks, under boards, and in debris. Centruroides are active foragers and do not burrow. It is common for them to climb, and many reports in homes are associated with attics.
Scorpions remain sheltered in the daytime and become active at night.
Their bodies are covered with a waxy cuticle which also helps reduce water loss. For reasons yet unknown, the scorpion cuticle fluoresces under ultraviolet light i.e., a blacklight. Reaction to the bite may vary based on sensitivity of the individual. Deaths attributed to this species are not well substantiated. There are no scorpions in Texas that are considered lethal to man.