This page has moved. Click here to view. Schamberg's Disease and Other Nonpalpable Purpuras Nonpalpable purpuras include thrombocytopenic conditions, senile or actinic purpura, blood clotting abnormalities, Schamberg's disease, hypergammaglobulinemic conditions, and disseminated intravascular coagulation.
Minor trauma induces ecchymoses, usually on the dorsum of the hands and forearms.
The skin in these areas is thin and fragile. Topically or systemically administered steroids can induce similar purpura. Other causes of vascular fragility of the skin include amyloidosis and the Ehlers-Danlos syndrome. The lesions have the appearance of Occasionally Schamberg's disease is secondary to a drug reaction. Petechiae and purpura also occur in hypergammaglobulinemic purpura , a syndrome characterized by episodes of fever and arthralgias which appear to be the result of immune complex-mediated damage to small blood vessels.