This interest was first aroused because of the growing use of X-rays. Two researchers, Dr. C.E. Collins and his son, Creston, began to investigate aloe as a means to cure X-ray dermatitis. This initial research prompted more research. During the early 1990s, articles published in the Journal of the American Podiatric Medical Association pointed to aloe as having antibacterial, anti-inflammatory, and antiseptic properties. A University of Texas research team discovered that aloe may penetrate injured tissue, relieve pain, and dilate capillaries.
Research also points to the value of mucopolysaccharides, one of the constituents of aloe vera.
Many studies suggest that mucopolysaccharides are responsible for aloe's wound-healing activity because they act as a growth factor. Acting synergistically, aloe vera may keep the wound moist, and, at the same time, allow oxygen to penetrate the wound, adding to regeneration. This is further confirmation of case reports by El Zawahry, et al. Because aloe penetrates deeply into the skin, it is possible that the aloe could carry harmful substances into your skin if it is not clean. Shelf life is 3 years, unopened.