Non-allergic OR caused by corrosive chemical gases such as ammonia, chlorine, acids and vinyl chloride can cause significant inflammation and permanent damage. Some non-allergic forms of OR may occur at first exposure to a substance, whereas allergic OR may occur only after weeks or years of exposure and symptoms may not be present at the job site. SBS is mucous membrane irritation caused by inadequate air handling equipment in new, energy-efficient office buildings. People with this condition experience symptoms only in the affected building. Chemicals that may cause SBS symptoms include carbonless copy paper, photocopier fumes, cleaning agents, and solvents.
Medication is most effective for allergic OR and includes antihistamines and decongestants.