Lead the reviewer carefully. Outline benefits that will result from these data. Show how future studies will be able to build upon the results of this study. Background Provide a good review of the relevant literature and careful summary of relevant preliminary data. Include an appropriate rationale for the study being proposed in the application.
Specific Aims Give a limited number of specific goals for the application.
These goals should be focused and should be stated concisely and precisely. Avoid vague statements and broad sweeping all-inclusive hopes. Emphasize the collection and analysis of facts or the perceptions and experiences of the study cohort, not perceptions of the applicants. Research Design Keep the presentation of the design simple and logical. Give clear definitions for terms, study parameters, inclusion criteria, etc.