The complexity of development and its array of dynamic interactions is a formidable challenge to new investigators who wish to study developmental toxicology. Key to this is the use of appropriate experimental protocols that recognize the specificity of developmental damage with respect to timing and location within the embryo. In situ hybridization for localization of sites of expression of specific mRNA species. The Microanatomy Facility Core occupies a recently remodeled 300 sq.
Separate rooms house the laser capture microscope and incubators.
Wild MZ6 stereomicroscope equipped with a color CCT camera, jazdrive and screen for displaying, recording and distributing images. There is a Leica 2135 Microtome and Reichert-Jung cryostat for making tissue sections. For in situ hybridization procedures, sections are provided to the Microanatomy Facility Core, which then carries out the rest of the procedure. The benefit provided to Center investigators through the Microanatomy Facility Core include specialized procedures and technologies that are not generally affordable, accessible or maintainable within individual labs. The expert staff supported through the EHS Center greatly facilitates the ability to efficiently and consistently obtain high quality results.