They are very heat and drought tolerant once established, and will grow especially well in seaside gardens, tolerating salt spray and wind.
Oleanders generally grow best in the coastal areas of South Carolina.
Most cultivars will be damaged or killed by winter cold in the Midlands and Piedmont. In some protected areas mature plants may reach up to 20 feet tall. Some dwarf cultivars stay as low as 3 to 5 feet. Established plants that have been damaged by cold will regrow very quickly from the base. Their quick growth rate and thick multi-stemmed habit makes them ideal for use as a screen or informal hedge.