At this point on, the process is known as the common pathway. Factor X is activated by both Factor IX and Factor VII and converts Factor II, called prothrombin , into thrombin . APTT is used to screen deficiencies of the clotting factors, and PT is used to evaluate the extrinsic pathway. Once the body has healed itself and the blood vessel has been repaired, the clot is removed. The body does this by the fibrinolytic mechanism known as fibrinolysis.
Plasma contains the substance called plasminogen.
It is the activation of the coagulation system to convert plasminogen to protease plasmin, which removes the clot by breaking down the fibrin into smaller pieces known as a fibrin-split products. Its the fibrinolytic system that makes the network free from fibrin clots.