All the respondents we are looking at here agree with Parmenides that there is no unqualified change. There is change, but all of it has to do with changing arrangements of or relations among the basic entities. Seemingly not, since a genuine mixture is a new entity in which the composing elements exist no longer in their own right but only through the powers with which they endow the composite mixture. The atoms are indivisible, imperishable, eternal, homogeneous. The atoms have shape, motion, and weight, and differ from one another in these properties.
Motion takes place in the void.
Acknowledge that animals, plants, etc. are really real and try to show how unqualified change is after all possible. Retain reductionism, but conceive of the basic entities in such a way that they have the above properties. In every macro-entity one or more particular kind of seed dominates. Oh, by the way, natural processes are governed by Nous .