Fatty foods may increase the bioavailability of albendazole up to 4-5 times. Pregnancy C - Safety for use during pregnancy has not been established. Precautions Discontinue of LFT enzymes rise. May restart when LFTs are at baseline levels. Not advised during pregnancy if avoidable.
Prevention consists of improved sanitation and education about the disease.
In endemic areas, school screening has been shown to be effective in detection and early treatment of asymptomatic carriers. Untreated intestinal obstruction may lead to bowel necrosis, peritonitis, sepsis, and death. Treatment of most cases of ascariasis with appropriate antihelminthic agents is quite successful. In 1990, Kern described a case of cerebral Ascaris infection of a woman who subsequently died of cerebral necrosis. A pitfall to be avoided is the use of an antihelminthic, such as pyrantel pamoate, that causes spastic paralysis of the worm, in a patient with suspected intestinal obstruction due to ascariasis.