We who live in the middle know that. It is our daily experience. There is disorder and decay all around us. The whole creation groans. The groanings can be heard in the earthquakes and tornadoes and storms and fires that turn order into a pile of disordered rubble.
Many creatures are no longer fruitful and nor do they multiply as they once did.
Species go extinct, and every attempt to save one destroys two more. We can't seem to step anywhere without having a negative impact on the surrounding environment. The technologies that save us time and labor also pollute our water and air. Our main form of transportation, the automobile, kills thousands of people every year. There's a big hole in the atmosphere, we are told.