There have been individual exceptions to this rule, but the routine use of steroid, based on current evidence, cannot be supported. As many as ten percent of patients will have significant residual weakness and a few patients never fully recover. There is a chronic demyelinating neuropathy which is related to Guillain-Barre, although usually not a direct outcome of it. This is known as chronic inflammatory polyradiculoneuropathy. The condition has a relapsing course and often presents with asymmetrical, painless weakness and sensory loss.
Metabolic disorders are the most common causes of neuropathy in our population.
Segmental loss of myelin and degeneration of axons both occur. Postulated causes of the neuropathy include a metabolic abnormality and diffuse microvasculopathy. Autonomic neuropathy is frequent and is manifest primarily by atonic bladder and impotence in male diabetics. Abnormal sweating and blood pressure instability are often seen. Proximal Mononeuropathies Involvement of femoral nerve and lateral femoral cutaneous nerve may produce proximal symptoms.