Davis Alzheimer's Disease Center in Martinez are seeking healthy male volunteers to participate in a study evaluating the safety and effectiveness of a medication on a type of memory known as working memory. Neither the participants nor the staff will know which type of medication the participant is taking.
Researchers hope to determine how well the medication is tolerated, absorbed and metabolized.
Potential adverse effects include headache, dizziness, nausea, fatigue and increased heart rate. To participate, male volunteers must be aged 18 to 40 and be free of any significant medical or psychiatric history, including history of head injury or substance abuse. Participants will be required to visit the Alzheimer's Disease Center at 150 Muir Road five to six times. Each clinic visit will include a urine test for drug screening purposes. Blood also will be drawn at most visits, and psychological and memory tests will be given at three of the clinic visits.