Others are female and require a perfect-flowered or male cultivar for pollination. Many wild grapes are male vines and will not produce fruit. Cultivars such as Fry, Higgins, Scuppernong, and Jumbo have flowers with only female flower parts and must be planted near a perfect flowered cultivar. Additional cultivars that do well in North Carolina include Doreen, Nesbitt, Noble, Regale, Tara, and Triumph. Muscadine grapes are well adapted to the coastal plains and eastern pediment where temperatures seldom fall below 10 degrees F. Considerable injury generally occurs where winter temperatures drop below 0 degrees F. Some of the most cold-hardy cultivars include Magnolia, Carlos, and Sterling.
Muscadines have a high degree of tolerance to insect and disease problems.
Plant in full sun. Fruit set and production will be reduced if the vines are shaded for more than a few hours each day during the growing season. Muscadine grapes will survive and produce a crop on a wide range of soils as long as soil drainage is good. Plant failure can be expected in locations where water stands for even short periods after heavy rains. Soils with a hardpan should be avoided, as well as those high in organic matter.