Otherwise, try to be a detective and help your doctor find a cause when you discuss treatment. Keep track of when the hives come, how much Benadryl you are taking and when, and any other symptoms. Usually, treatment is effective. Sometimes, the cause isn't found. Mike, sarcoid varies quite a bit.
Some people do very well with steroids.
I don't know of any other commonly used treatment, and a quick review of some literature indicates that a few other drugs have been tried, but none that are well studied. They include some drugs used to treat malaria, viral infections, and inflammation. I've been to the doctor serveral times but he has not been able to diagnose my problem. The pain at this time is present most of the time. It wakes me at night and keeps me from performing my job because I can't bear the pain.