Pour the mixture into the enema bag. Administer the enema high. Repeat every 6 hours until good results are achieved. Managing bowel elimination problems in patients with cancer. Nausea may occur with or without vomiting.
Tolerance usually develops to nausea after several days of opioid therapy.
Vomiting accompanies nausea more often when constipation is not well-controlled. Any complaint of nausea or vomiting warrants a thorough bowel assessment and intervention as described. It may be necessary to use this antiemetic therapy on a scheduled basis for the first week of opioid therapy, after which it can be discontinued if nausea disappears or used on an as needed basis. Sedation may occur at the onset of therapy but usually disappears after a few days. It seems to elicit an overreaction by physicians when it occurs in their patients and is often the reason cited by the patient for abandoning the drug.