She died 3 days later. Autopsy showed accumulated fluid in the lungs, enlarged pale liver, congested heart, spleen, and kidneys and low level of lymphocytes. Highest rate among ward aids. B.Morphology 1.Spherodal but pleomorphic. Mouse urine and droppings are full of shed viruses and passed on to humans via direact contact with excretions or by rat bite or by eating contaminated food or by breathing in aerosolized urine or when mice are prepared and eaten.
Transmission is highest in the dry season.
In most patients, it is asymptomatic but in the others, a severe multisystem disease. Infections per year estimated at 100,000 to 300,000 with 5000 deaths. Virus initially replicates at site of infection - lungs or blood from cut skin. Later the greatest amount of virus in found in spleen, lymph nodes and bone marrow. It has an incubation period of 1-3 weeks followed by fever, sore throat, weakness, and malaise.