It rapidly distributes to tissues and is about 10-times as potent as diazepam. The depressive effects last from 8 to 12 hours. There are anecdotal reports of it being smoked. Drowsiness, dizziness, ataxia, nightmares, headache, and memory impairment have occurred following the administration of flunitrazepam. Symptoms of overdose include somnolence, confusion, respiratory depression, impaired coordination, slurred speech and seizures.
Treatment includes supportive measures, but flumazenil can reverse the sedative effects.
Flunitrazepam is commonly abused with alcohol. Taking flunitrazepam with other CNS depressants is extremely dangerous. Education is the best way to prevent disasters due to drug abuse. Health professionals should be part of the solution. Refferences Bond A, Seijas D, Dawling S, et al.