Generally, give the patient a combination of antibiotics and folic acid for a few months. Patients who have symptoms lasting longer than 6 months may be given the combination for as long as a year. Assess patients' responses by improvement of symptoms, weight gain, and correction of anemia. The duration of treatment depends on duration of symptoms. These vitamins are required for normal erythropoiesis.
Minerals are also nutritionally essential.
Iron replacement therapy is used in patients presenting with iron deficient anemia. Antibiotics are another category of drugs that are beneficial to patients. It is possible that by early eradication of bacteria pathogens, the gut is relieved of continuing injury. They are water-soluble vitamins that are used in nucleic acid synthesis and are required for normal erythropoiesis. They correct megaloblastic anemia resulting from folate and B-12 deficiencies.