Click here to go to the Histopathology homepage. General pathology is the study of the basic reactions of cells and tissues to the abnormal stimuli that underlie all disease. The nucleus contains the nuclear chromatin and the nucleolus. The smooth endoplasmic reticulum is mainly concerned with lipid metabolism.
Mitochondria are the source of energy production by oxidative phosphorylation.
Glycogen granules act as an energy store. The lysosomes are membrane-bounded bodies that contain cocktails of enzymes. A good example would be the change that occurs in the muscle cells of weightlifters. The weightlifter's biceps is so much larger because the individual muscle fibres have undergone hypertrophy . Hypertrophy is defined as the adaptive response of increasing cellular mass to maintain viability at higher levels of metabolic activity.