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Repetitive Strain Repetitive strain injury, or RSI, is a condition caused by repeatedly putting your body in positions that cause unnecessary stress. Slouching, improper lifting and poor sleeping positions can all lead to its development. All of these activities cause irritation and damage to tendons, muscles, nerves and other soft tissues. A majority of cases of chronic low back pain may be caused by abnormalities in gait, US researchers suggest. They report that the use of corrective shoe inserts appears to provide more effective back pain relief than standard therapies.