White and Fenner ch. Wagner and Hewlett, Ch. 2, 3.
Pathogenesis is the ability of one organism to cause disease in another.
It could be thought of as a normal departure from the normal physiological parameters of an organism. In terms of virus infection pathogenesis results either directly from virus infection or from the response of the host to the virus Inflammation, headaches, fever and sometimes skin rash are the effect of the host response to virus invasion in the production of interferon and other cytokines. The vast majorities of virus infections are non-pathogenic and do not result in the disease state. E.g. rabies in foxes or other wild animal. Man is accidental host.