The significance of the project is that it makes the methods and data of QM readily available to the community, organizes structural information hierarchically, and provides new research tools. The new tutorial supplies training in QM, which include morphometry, stereology, and reconstruction, through use of detailed descriptions, worked examples, calculation workscreens, simulations, and toolkits. The databases include a tutorial, data entry forms, published data and query tools.
Reports allow end-users to standardize, recycle, and create new data.
A new representation of QM data, called the structural phenotype, simplifies the task of searching for structural analogies and generalizations across the literature. The project actively supports the use of QM and contributes a structural component to Biomatrix. Furthermore, the investigator will begin to port his work to the workstation environment. This proposal is being jointly supported by the Applications of Advanced Technology program in the Directorate for Education and Human Resources as well as the Computational Biology Activities program.