Major role in wound contraction. TEM shows an external lamina. Macrophage Usually irregular in shape with vacuolated cytoplasm. The macrophage is difficult to distinguish from a fibroblast without the presence of phagocytosed material. A relatively large cell frequently found near blood vessels.
Numerous granules show metachromasia with some stains.
Releases histamine, heparin, slow-reacting substance of anaphylaxis and eosinophil chemotactic factor. Plasma Cell Eccentrically placed nucleus with round shape. Negative Golgi and basophilic cytoplasm are evident. Formed from B-lymphocyte. Synthesizes and secretes antibodies.