Mathematical model of a virus-neutralizing immunglobulin response. Protective immunity does not correlate with the hierarchy of virus- specific cytotoxic T cell responses to naturally processed peptides. T lymphocytes visualized using soluble tetrameric major histocompatibility complex class I-peptide complexes. The proteasome inhibitor lactacystin prevents the generation of an endoplasmic reticulum leader - derived T cell epitope. PrP expression in B lymphocytes is not required for prion neuroinvasion.
T lymphocyte responses to viruses bearing variant epitopes.
Dendritic cells efficiently induce protective antiviral immunity. Dendritic cells induce autoimmune diabetes and maintain disease via De novo formation of local lymphoid tissue. IgD can largely substitute for loss of IgM function in B cells. Effector pathways of natural killer cells.