Because of their pronounced biological effects, MAs III and DMAs III may become sensitive biomarkers of arsenic toxicity in humans. Metabolism and toxicity of arsenicals in cultured cells. Comparative toxicity of trivalent and pentavalent inorganic and methylated arsenicals in human cells. Arsenicals inhibit thioredoxin reductase in cultured rat hepatocytes. Vega L, Styblo M, Patterson R, Cullen W, Wang C, Germolec D. Differential effects of trivalent and pentavalent arsenicals on cell proliferation and cytokine secretion in normal human epidermal keratinocytes.
Selenium modifies the metabolism and toxicity of arsenic in primary rat hepatocytes.
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