Because the condition is rare it is unlikely that large scale studies of alternative treatments can be organised. Bearing this in mind it would probably be appropriate in patients under the age of 60 to consider some form of bone marrow or stem cell transplant if the disease could be brought under some form of control and the general condition of the patient was satisfactory. There is a Leukaemia Research Fund booklet on Bone Marrow and Stem Cell Transplantation . Secondary plasma cell leukaemia usually occurs late, and often as a terminal event in patients who have been on treatment for myeloma for some years. In these heavily pre-treated patients it is unlikely that even aggressive therapy would be effective against their illness.
Prognosis See above.