Trite statements that schizophrenia is a brain disease have been made since the concept of schizophrenia was established. There is a real difference between schizophrenia and cancer, which means that understanding cancer cannot be a suitable model for schizophrenia.
Psychosocial factors are integral to the causation of schizophrenia.
The suggestion that misregulation of information processing is a final common pathway for schizophrenia is a tautology that does nothing to improve understanding. Nongenetic factors may have more significance than merely influencing brain development. Such ideology is defensive and avoids personal agency. Reducing relations between people to objective connections seems to make them more manageable. However, modern psychiatry has again become so dominated by biologism that debate about the relationship between mind and brain is now rarely acknowledged, as evidenced by the bias of the editorial by Andreasen.