The mechanism resembles an irritative and toxic type of eczema except for the absence of leisions.
Smoking is an established aggravating factor.
No immunological mechanism has been demonstrated. The acrylate family can be divided into resins ans glues. Methyl methacrylate is the monomer for acrylic resin polymers. Inhalation of cyanoacrylate glues may provoke an asthmatic attack. Recurrent eczema may be observed.