This would require the runner to adjust his speed, slowing on the uphill and accelerating on the downhill. 5 beats from the target. If you are an inexperienced hill runner this means slowing more than you might normally on the uphills and running much faster on the downhills. Caveats As mentioned before, it is important to establish your personal pulse rate responses. If the numbers in the table above for your age don't seem to match your maximum pulse rate, then determine what it really is and figure your training numbers out based on your max.
Medication can affect heart rate.
If you are taking oral asthma, blood pressure, thyroid or heart regulating drugs, discuss the possible effects to resting and training pulse rates with your physician. Any unusual heart rate response should be checked out by your physician. Heart rate is affected by temperature, rising with high or low temperatures that require your body to use additional energy for temperature regulation. It is also affected by stress or illness. All these effects act like an elevated resting heart rate.