If neutrophil function were controlled by a single signaling system, a defect would stop all aspects of activation. The activities of neutrophils are usually beneficial and protective but they can cause extensive tissue necrosis under certain conditions. There are some circumstances in which neutrophils play a pathogenic role. This role is accomplished through a deregulated control of their effector functions or through their continuous activation. Many studies have shown , neutrophil oxidants and proteases working together or as individuals appear to be responsible for much of the tissue injury occurring under the above conditions.
Neutrophils are complex cells that are needed for mammalian life.
As you can see the cell s morphology plays an important role to the cell s complex function, phagocytosis. Neutrophils help keep invading pathogens from harming the body through this process. Phagocytosis is regulated through many different steps to insure that no harm is done to the host s tissues. Even though there may be harm to the host s body due to neutrophils, without them disease would be uncontrollable. Demaurex, N., G.P Downey, T.K Waddell, and S. Grinstein.