Critical Care University of Chicago Chicago, Ill 1. Pharmacologic treatment of cancer pain. N Engl J Med. J Pain Symptom Manage. Methylnaltrexone for reversal of constipation due to chronic methadone use.
Oral naloxone antagonizes loperamide-induced delay of orocecal transit.
Dig Dis Sci. Oral naloxone in opioid-associated constipation. Methylnaltrexone was originally formulated and subsequently modified by faculty at the University of Chicago. The University of Chicago and Drs Yuan and Foss stand to benefit financially from the further development of methylnaltrexone. All rights reserved.