University of Iowa Crohn's Disease Crohn's disease is an inflammatory disease of the intestines.
Most cases start in the small intestine.
Alternating states of flare-ups and remissions can last a lifetime. There is no cure for Crohn's disease. Treatments work to control the disease and relieve symptoms. Anti-inflammatory drugs, such as steroids or medicines that suppress the immune system may be given. A well-balanced diet with supplemental fiber is an important part of treatment.