Hemoptysis is rare, as is production of sputum. Lymphadenopathy is very common in sarcoidosis. Peripheral lymphadenopathy is very common, particularly the cervical, axillary, epitrochlear, and inguinal nodes. Unlike nodes in tuberculosis, they do not ulcerate. The skeletal involvement in sarcoidosis has been reported with the most common sites being the hands and feet.
Patients often complain of morning stiffness and pain and demonstrate limitation of motion.
The bone lesions are variable size cysts, osteopenia and punch out lesions. Parotitis occur in a minority of cases but should alert the clinician to the diagnosis. Cardiac involvement may be evident as a conduction defect on electrocardiogram. Central nervous system changes have been described, including diabetes insipidus and seizures. The most common presentations of neurosarciodosis relate to meningeal, hypothalamic and pituitary involvement.