NCM has also occured in those with only a few satellite nevi. Most moles are harmless, but some moles do have a greater chance to develop melanoma. These include larger moles, very dark moles, and moles with varying colors. Changes in growth, in color, in surface texture, pain, bleeding, or itching are all of concern. Any such changes should be evaluated medically if they last longer than 2 weeks.
Pregnancy increases the production of melanin in the body.
There is currently no evidence that pregnancy increases the risk of melanoma for women with large nevi. For unknown reasons, melanoma has so far never occurred in the satellite moles of someone with a large nevus. Because of this, removal of satellites is often cosmetic only. Coarse hair sprouting from a satellite can persist even after excision of the satellite because the hair root is very deep. Two have hydrocephalus with or without seizures.