Follow-on studies could target liver diseases, abdominal surgery prophylaxis or liver transplant. An autoimmune disease where T cells stimulate the body's own skin cells. Initial preclinical and Phase I healthy adult studies reported in the literature were performed with rBPI-23. Bacteremia means the detectable presence of bacteria in the bloodstream. Meningococcemia is a septicemia caused by meningococcal bacteria.
Septic shock refers to the dangerously low blood pressure caused by sepsis.
The order in which amino acids occur in a protein or peptide. Sequences uniquely define a particular peptide or gene sequence and can sometimes be patented. In autoimmune diseases T cells mistake the body's own cells for foreign cells and attack them. Peptide molecules that bind to T cell receptors and reduce the autoimmune response have shown potential in treating autoimmune disease. Normally, a population of bacteria live harmlessly, even helpfully, inside our lower GI tracts.