Neurones communicate through specialised structures called synapses.
Far from being static, synapses experience morphological and functional changes. One aspect of this is the production of new molecular components and removal of spent ones. We are interested in the properties of these channels, and how they produce a synaptic current of a particular magnitude and time course. One important focus of the research is the mechanism that produces different molecular versions of these channels, and how each channel version affect synaptic function. Coupling of electrical activity to gene expression of acetylcholine receptors .