No specific interactions.
Marked hypotension is seen in patients requiring hemodialysis.
3 I.V. bolus injections of 5 mg each, at 2-min intervals. If hemodynamically stable, give 50 mg P.O. q6h starting 15 min after last I.V. bolus and continue for 48 hr. Continue for at least 3 months. Effects of metoprolol may be elevated when used concomitantly with histamine antagonists, hydralazine, monoamine oxidase inhibitors, and propafenone. Metoprolol may increase the effects of benzodiazepines.