EN should be considered as a warning signal of impending relapse in a patient with a history of Hodgkin's disease. Dental treatment and the possible presence of infectious dental foci should be considered in the differential diagnosis. EN is reported following dental treatment associated with gingival bleeding or due to infectious dental foci. There are several associated conditions that these disorders have in common. The appearance of both conditions in the same patient has been reported.
New etiologies continue to be described.
Patients with GI symptoms should have a stool culture for Y. enterocolitica , Salmonella , and Campylobacter . EN in most instances is a self-limited disease and requires only symptomatic relief with salicylates and bed rest. Cases that are recurrent, unusually painful, or long lasting require a Potassium iodide may be given in doses of 300 mg orally three times each day for 3 to 4 weeks. Relief of lesional tenderness, arthralgia, and fever may occur in 24 hours. Most lesions completely subside within 10 to 14 days.