Most people will agree that drinking that much fluid in the form of plain water is boring. So the experts have altered their recommendation, stating that any clear fluid is acceptable. Sports drinks like Gatorade are acceptable in small doses. But their sodium content may be a little high for exclusive use. Other drinks such as coffee or, carbonate and caffeine laced sodas are discouraged because the effect can have the opposite of what the patient is trying to accomplish.
Sodas can cause head aches and coffee can increase diarrhea.
For patients that are on any type of therapy, whether it be mono or combination, it is vital that they consume as much water as they can handle. The Interferon works best if it is flowing through out the body by way of hydration. It assists the toxic chemicals out of the body instead of holding on to them and making the patient feel bad. Good article I've been going around with my water glass or bottle since I was diagnosed. Its especially important for me on combo.