We are studying both aspects protein structure and interactions between proteins. We accomplish this using a variety of computational and experimental methods. Structural Bioinformatics and Experimental Studies of Protein Structure and Function.
Proteins are the cellular machinery.
Often this involves proteins interacting with one another. How these proteins recognize each other in the crowded cell environment and how they physically interact with one another are of great interest. They are involved in numerous vital processes such as cell motility, signal transduction, transcription and the immune system. This is the same conformation as adopted by a single strand of collagen. We are elucidating the physical determinants of PPII helix formation using both computational and experimental methods.