In multicellular eukaryotes, two copies of the genome are often present. Some eukaryotes such as plants have many copies of the genome in each cell. Each chromosome consists of a single DNA double helix. Ends of the chromosome, called telomeres . The minimal requirement for a chromosome to propagate itself in a cell is to have a replication origin, two telomeres, and centromere.
Replication origins are where DNA replication is initiated.
Telomeres consist of repetitive sequences that reside at the end of a linear chromosome. Telomeres protect the DNA from degradation. Bacterial circular chromosomes lack telomeres. The chromosome is attached to the cell membrane, which provides a mechanism for its proper segregation during cell division. Plasmids are not attached and partition randomly.