Death is usually due to respiratory failure by paralysis of the intercostal muscles and diaphragm. In 1988, the World Health Assembly established the year 2000 for achieving global poliomyelitis eradication. By 1994, the Americas were certified as polio-free. All other regions are making steady progress towards this goal. The WHO reports that global eradication of poliomyelitis is still on course for the year 2000.
Many types grow very poorly in vitro.
Little consequence in itself, but predisposes to secondary bacterial infections - a major problem in infants and elderly. There is little or no cross-protection between serotypes. To view a computer generated animation of a rhinovirus particle, click here . This image is based on the real atomic co-ordinates of rhinovirus 14. The antigenic sites on the surface of this particle are highlighted in purple.