Through loss of nitrogen, diazomethane forms a carbene which posesses a highly electrophilic double free radical. The clinical symptoms appearing in the work place are the only means of diagnosis. Significant amongst exposed subjects. IgE type allergy. Debris and dust from the breeding areas may also contain the allergen.
Sensitization is associated with humid environments.
Both the larvae and adult insects are source of allergens. Rhinitis and asthma linked to work. J. Allergy Clin. Occupational asthma caused by hypersensitivity to ground bugs. J. Allergy Clin.