Improving recovery time and decreasing the need for dialysis also has not been shown.
Urine output is increased which aids in clinical management.
However, there is one prospective, randomized, double blinded, placebo-controlled trial. Patients with prerenal disease, obstructive uropathy, glomerulonephritis, chronic renal failure, and systemic disease with renal involvement were excluded in all the studies. The three groups were similar. Patients were followed for 21 days. No significant improvement in mortality, length of renal disease, or need for dialysis.