MEK does not affect the blood-forming cells as lead exposure does. Finally, MEK does not cause genetic defects, nor does it cause psychomotor retardation. Remember, for any exposure, dose and duration are the critical factors for any manifestation of a toxic effect. Like any chemical or product, the first recommendation is to follow the manufacturer's recommendations on the proper personal protective equipment to use for each procedure. Beyond the manufacturer's specific recommendations, the technician must consider the basic factors of absorption, metabolism, and toxic effects.
Ventilation is the key factor to reducing the airborne concentrations.
When working with mixed solvents, be mindful that MEK can promote the effects of other solvents in the mixture. To limit both the skin and lung exposure to the mixture, use the approved shop hygiene methods. Examples include using MEK and other solvents only in a ventilated hood, opening only small quantities of the product as needed, and wearing an apron and face shield for splash protection. Finally, misuse of MEK and sloppy work methods can produce a vapor that has an irritating effect on coworkers who breathe the vapor. Throat and nasal irritation are the main clinical effects from a short term exposure.