Spinal cord cervical roots and lumbosacral roots are affected. They become filled with neurofibroma which cannot be resected. Schwannomas, involving both eighth cell nerves often occur in association with this type. In addition, with this more central type, you are at a high risk of additional primary CNS tumors of all types. Primary tumors of other organ systems do metastasize in.
Most tumors metastasize to the lung before proceeding to the brain.
Breast, prostate, melanoma, and kidney tumors are exceptions to this rule. Breast and prostate tumors metastasize to the dura and not to the brain. Melanomas and Kidney tumors metastasize to the brain directly. Melanomas have the greatest likelihood of getting to the central nervous system. In contrast, kidney tumors often do not appear in the brain until years after the primary lesion.