Having 2 sets of speakers helps. I suggest near field monitors pointing at you when you look at your computer screen and larger mid field monitors when you are facing your mixing desk. You switch back and forth as you build the song. Your tweeters should be at ear level. That's pretty important.
Speakers sound different off axis.
Build everything else around these considerations. Avoid putting speakers in corners. Move them a few feet out if it has to sit in a corner so you don't get an unwanted bass boost. When setting up or rearranging your studio, think of every possible angle by which you may need to access your equipment. If the jackfield is against a wall in the middle of a table, I can guarantee you you won't be repatching very often.