PyKDE advocates generally claim it's zippy, easy, and powerful. In early 2000, Python bindings for Qt and KDE have become quite capable. Pythonwin Pythonwin is available only for Windows. Its IDE is itself written in Pythonwin, and is impressive. Tkinter Tkinter 's the standard GUI toolkit for Python.
Many people protest that, and in fact have, for years.
It remains true. Those with an interest in Tkinter will want to read Fredrik Lundh's notes on Tkinter 3000, accessible through his Tkinter home page and Pythonware product page . Under UNIX, though, there are tons of impressive VTK examples that use python. It is built on wxPython, wxWindows and Python. Boa Constructor was inspired by and aspires to Delphi.