Medical therapy is rarely reported. Rarely, perilymph fistulas are associated with recurrent meningitis. Complications of surgery are unusual, although symptoms may persist. Due to the difficulty in making the diagnosis, the natural history of this disorder is unknown. Significant improvement in symptoms that are presumed to be from perilymph fistula may occur with conservative treatment.
Surgery is more successful in relieving vertiginous symptoms than in improving hearing.
In head trauma cases, hearing loss with vertigo suggests a perilymph fistula syndrome until proven otherwise. The perilymph fistula syndrome defined in mild head trauma. Perilymph Fistula Pathophysiology. Medicine is a constantly changing science and not all therapies are clearly established. New research changes drug and treatment therapies daily.