Uses linear discriminant functions combining characteristics describing various contextual features of polyA sites. Based on statistical estimation of expected number of a nucleotide consensus pattern in a given sequence. Uses datafile consisting of public release of Transfac sequences and a set additional functional motifs. SCAN2 performs alignment of two multimegabyte sequences. Both programs have Java viewer for easy visualization and parsing of results.
Program is useful to check location of oligos and their uniqueness in genome.
The program is based on complex neural-network recognizers, which identify probability of he subcellular localization in Nuclear, Plasma membrane, Extracellular, Cytoplasmic, Mitochondrial, Chloroplast, Endoplasmic reticulum, Peroxisomal, Lysosomal or Golgi compartments. NY 10604 tel.