Because you weigh 350, it seems to me like it's probably worth figuring out how you came to be at that weight. I hope I'm not making you feel bad by saying this, but 350 seems like a weight you don't get to unless you have an eating disorder, a hormonal imbalance, or a seriously effecient metabolism. If you have an eating disorder, you will probably want to talk with a therapist as a first step. For a hormonal imbalance, you would of course see a doctor. If you want to raise your metabolism so you can burn more calories, the best way I know of to do that is lifting weights.
More muscles burn more calories.
I've learned not to set myself really restictive diet goals, because I don't stick with them. I eat as healthy as I can. I do exercises that I enjoy doing, so I keep doing them. When you get used to your new level of activity and diet, you can bump them up another notch. I may never be skinny, but I'll be a lot less fat then when I started.