Bring age appropriate toys and games for your children to keep them occupied. Put each child's goodies in a special knapsack of backpack with their name. Don't let them see what's in it until your on the road, the anticipation is often as exciting as the contents of the bag. Don't over pack, you can pick up necessities at local stores on your trip. Bring snacks so that your kids won't get hungry in between meals.
Most stores carry individual servings of everything from peanut butter and jelly to carrots.
Give each child a single-use camera to take their own pictures. Some of the best photos can come from the pint-sized view of what's important. Also, take advantage of the airlines' pre-boarding opportunities for traveling with small children. Lastly, let the kids help plan the trip, this way there will be places on the itinerary that they want to see. This can be done easily with a Best Western traveler's guide .