Neuropathic pain is difficult to manage.
To some extent, the pain can be controlled by anti-inflammatory or opioid drugs. Therefore, the the post-receptor signal inducers that lie downstream from the receptor mediated responses may be involved in the persistence of the pain. The authors showed that in mice that lack of PKC g leads to In addition, PKC g was shown to be confined to a small subset of dorsal horn neurons. These findings, provide the potential molecular pathway which is involved in the persistence of pain and which may be used as a target for its treatment. Line Name DNA Construct 1.