Some bison cows have been documented to produce calves for 40 years. In contrast to a beef cow, bison stand facing into the wind and snow. Bison are very hardy, requiring no shade in the summer or shelter in the winter. They are very disease resistant. In fact, very few bison producers vaccinate for anything.
Parasite control is important.
Most producers report they treat with Ivomec one or more times a year. However, many producers do not treat at all. Foot rot is not considered a problem. On health issues, it is important to work with a veterinarian who is interested in buffalo. Transporting buffalo across state lines requires various paperwork and vaccinations.