The molecular weight is 104,000, and the pI is 4.5 - 5.5. Concanavalin A has widespread applications in carbohydrate research and cell surface research. A lies in its specific binding action with certain carbohydrate containing receptors. It agglutinates red blood cells and forms complexes with blood group substances, immunoglobulin glycopeptides and carcino-embryonic antigens. Concanavalin A exhibits mitogenic activity with lymphocytes.
Normal cells react after proteolytic treatment.
Purity is established by carbohydrate content and electrophoretic analysis. Supplied as a soluble, dialyzed, lyophilized powder. Store at 2-8 deg.