He observed changes in neuromuscular development, timing of puberty, accessory reproductive organs, liver enzymes, and socio-sexual behaviors. J. Guillette , University of Florida, Gainesville, summarized reproductive and endocrine abnormalities found in wildlife species exposed to various pesticides or metabolites. In ovo exposure of alligator embryos to EDCs, produced female neonates with ovaries that produce elevated testosterone and develop larger clitori compared to controls. Mixtures of estrogenic and anti-estrogenic contaminants produced intermediate, mixed gender individuals. J. Pete Myers , W. Alton Jones Foundation, Charlottesville, Virginia, discussed recent efforts being taken by the EPA to screen for EDCs.
Research funded by industry routinely fails to confirm academic results.
Their attempts to reproduce the work also failed to reproduce the positive controls. Simultaneous to the EDC symposium were presentations by C.M. Olsen, L.A. Fowler, N.J. Place, A. Cheek, N.C. Noriega, E.F. Orlando, and K.L. Howdeshell. The following are summaries of observed papers. However, PCBs do bind to the transport protein transthyretin with the same affinity as the natural ligand. She concluded that disruption of thyroid homeostasis by OH-PCB or DDT is more likely to occur via interference with serum transport than receptor interaction.