Paul Broca was able to lateralize motor speech to the right side of the brain by observing a lesion in the right frontal lobe of a patient. Scientists propose hypotheses to explain facts and they are usually correct in their predictions. Galen proposed that functions were localized to fluids contained in the ventricles of the brain. Phrenology is the study of landmarks on the brain surface believed to be associated with characters and morals.
Microglial cells are mesodermal in origin.
MAP2 and TAU are microtubule-associated proteins which stabilize the cytoskeleton. MAP2 is found in axons while TAU is found in dendrites. Albert Einstein's brain was found to contain a much higher than average number of neurons in the cerebral cortex. The cytoskeleton gives the cell its shape. Resulted in the discovery of norepinephrine as a major brain system.