Nefazodone hydrochloride is a synthetically derived phenylpiperazine antidepressant.
The molecular formula is C 25 H 32 ClN 5 O 2 HCl, which corresponds to a molecular weight of 506.5. Nefazodone is a nonhygroscopic, white crystalline solid. It is freely soluble in chloroform, soluble in propylene glycol, and slightly soluble in polyethylene glycol and water.