Bettie Sue Masters' laboratory is looking for two postdoctoral fellows to pursue two areas of research, which could be adapted to suit the interests of the applicant. Dr. Masters is funded to study the structure-function relationships of the nitric oxide synthase isoforms and cytochrome P4504A systems. Dr. Masters' laboratory is also studying all three NO synthase isoforms, including endothelial NOS, and is interested in pursuing the possible relationship between these systems. Neither we nor anyone else have approached the ultimate knowledge of the structure-function relationships governing the activities of the three isoforms of nitric oxide synthase, as well as differentially processed forms found in various tissues. Her laboratory has brought many biophysical techniques to bear on this problem in order to provide insight into the structural properties that determine their individual functions.
Positions are available immediately at entry or advanced levels of postdoctoral experience.
The Cys331Ala Mutant of Neuronal Nitric Oxide Synthase is Defective in Arginine Binding. The Influence of Cofactors. Inducible Nitric Oxide Synthase Generates Superoxide from the Reductase Domain. Involving a Novel Metal Center. Stimulatory Effects of Hofmeister Ions on the Activities of Neuronal Nitric Oxide Synthase.