In Queensland, where it is notifiable, there have been no reported cases for some years. LGV is caused by specific serotypes of Chlamydia trachomatis . These serotypes differ from those implicated in other chlamydial genital infections.
Primary infection causes a small genital lesion which is usually trivial.
However the ensuing chronic infection may cause significant destruction of regional lymph nodes and perigenital tissue. Early and prolonged treatment is required to reduce the chronic phase of infection. Patients with LGV must be screened for other STIs, especially syphilis. LGV may facilitate the transmission of HIV infection. TOP OF PAGE Aetiology and epidemiology Lymphogranuloma venereum is a systemic disease caused by Chlamydia trachomatis , predominantly serotypes L1, L2 and L3.