Next month, we will include Indinavir. Thank you very much. D4T, ddI and Indinavir is one of the very reasonable potent regimens. In one study called Start II, the average CD4 count increase was about 150 cells over one year. It is very possible that your wife could go as high as 300.
Resistance is very variable.
If the regimen works well, and if your wife is very careful about taking all of the doses exactly on time, it is certainly possible to go at least 3 years with no resistance. Once the viral load is undetectable, it is probably not as important to check every 3 months, as we usually recommend. However, early on it can be very important to see if there are problems with the treatment. I might suggest, if you can afford it, to test at Month 1, Month 4, Month 7 and then every 6 months. Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material.