Often severe, this results from intracranial pressure from the pituitary tumor expanding the sella turcica. One of the more frightening symptoms is a narrowing of vision, usually starting from the periphery. This results from pressure on the optic chiasma by a growing adenoma. Observable signs in other body areas can help clarify a differential diagnosis. Relatively recent growth of the feet and hands show themselves as an increase in ring size, due to the increased diameter of the carpal bones.
Patients often report a sudden increase in shoe size.
The disturbance in normal endocrine functions caused by the adenoma often starts a cascade of hormonal dysfunction. A disruption of nearly every aspect of sexual and reproductive functions may ensue. Low blood sugar, low blood pressure, weakness and fatigue are common. Visceral organs can expand, and at the same time be reduced in their functionality. A dysfunctional adrenal system can result in adrenal insufficiency, and seriously compromise the body's ability to deal with even mild stress.