Indomethacin is an anti-inflammatory drug which is indicated for the treatment of moderate to severe rheumatoid arthritis, gout, bursitis, andosteoarthritis. It acts in the body by inhibiting the synthesis of a group of compounds called prostaglandins.
Prostaglandins are a part of a cascade of factors leading to inflammation.
Should you notice your stools suddenly become darker in color please contact your physician immediately. Diflunisal andprobenacid which increase the blood level of indomethacin and its side effects. Indomethacin may potentiate the effects of methotrexate, lithium and cyclosporin and increase side effects of those compounds. Occasionally, indomethacin may increase the blood levels and side effects of digoxin. Do not use with diuretic triamterene.