Mules can bray like donkeys or whinny like horses. A mule's foot is more elastic, upright, and boxlike than a horse's. A healthy mule foot on a horse would appear to be a very contracted foot. A mule's hoof is more supple and less likely to chip than a horse's. Some mule hooves grow continuously, without wearing down or chipping, which can be crippling if not trimmed.
Mules require the same vaccinations and parasite control as horses.
Regular dental care, as well as hoof care, is needed to maintain health and soundness. The difference between horses and mules is in their care and feeding. The most common problem is overfeeding. Mules need less protein than horses and show ill side effects if fed too much. Grass hay with a small ration of a complete vitamin and mineral feed is the best diet.