Maintains plasma glucose concentrations during fasting. In muscle, glucose 6-phosphate is converted to pyruvate and lactate, which goes to liver and is converted to glucose. FFA and glycerol are converted to glucose. Occurs in adipose cells. Glycerol goes to liver and is converted to glucose.
Most organs reduce glucose utilization and use fatty acids.
Lipolysis gives glycerol and FFA's. Glycerol goes to glucose. All are released by pancreas. Insulin - promotes glucose uptake and utilization and activation of storing enzymes. Increases glycogen synthesis, triacylglycerol synthesis and protein synthesis.