Ergotamine can be taken under the tongue. When combined with caffeine it is taken orally. It is also available as a suppository in combination with caffeine. Do not use this drug more often or in higher doses than your physician recommends. Ergotamine should not be taken more than 2 days a week, and at least 5 days apart.
Overuse can lead to more headaches.
Dihydroergotamine is given as an intravenous or can be taken as a nasal spray for emergency treatment of migraine. Call your physician immediately if you experience confusion or anxiety, vision changes, chest pain, increased blood pressure, arm, leg, foot, or back pain, cold or blistered hands or feet. Also, tell your physician if your migraines became more frequent or intense since you started taking the drug, or if it no longer works as well as it did at first. Do not try to make the drug work better by increasing the dose. If you are also receiving injectable epinephrine or other ergot drugs, your physician may need to adjust your dosage of ergotamine.