An experimental laser treatment for small, localized breast cancer tumors could become a less-invasive alternative to lumpectomy for some patients, researchers reported today. It would be a much simpler procedure to do, with a lower risk of complications, and no hospital admission required in patients who are otherwise generally fit. Before the laser treatment, patients have a diagnostic MRI scan. Then, under image guidance, thin needles threaded with optic fibers are inserted into the tumor via the skin, followed by the delivery of low-power laser light to gently heat and kill the tumor tissue. After the laser treatment, patients have a second MRI scan, at which time the researchers assess whether any areas of cancer can still be detected.
Patients then undergo conventional surgery to remove the entire cancer area in the breast.
Following surgery, excised tissue is examined under a microscope and compared with the MRI images. Dr. Bown and his colleagues found good correlation between the post-laser MRI images to see if the imaging picked up any areas of cancer not adequately treated with the laser. In the study's next stage, which is just getting under way, patient volunteers will receive only the experimental laser treatment without subsequent surgical lumpectomy, but with close MRI follow up. According to the researchers, laser treatment could be a suitable alternative to lumpectomy only for carefully selected patients with small, localized breast tumors. Since 1992, the BCRP has been working to prevent and cure breast cancer by fostering new directions in research, addressing underserved populations and issues, encouraging the work of new and young scientists and inviting the voice of breast cancer survivors to be heard in all aspects of the program.