To date, the agreement remains uncompleted and unsigned. The main cause for the decline of the Flat-tailed Horned Lizard is conversion of habitat to urban and agricultural uses. The various uses include crops, cities, off highway recreational use, geothermal leases, military maneuvers, gravel pits, highways, etc. In 1907, flood waters broke through dams creating the Salton Sea in California and covering habitat in water. Other factors responsible for the decline of this species include the use of pesticides on crops to control beat leafhoppers.
Pesticide drift is thought to affect ant populations in adjacent habitat.
It is unknown what the effect of pesticides is on lizards themselves. References Bryant, Harold C. 1911. The horned lizards of California and Nevada of the genera Phrynosoma and Anota. Ditmars, Raymond L. 1949. In The reptiles of North America.