Fucose binding protein Localized to apical region of sperm head 75 . An integral plasma membrane protein was purified using wheat germ agglutinin lectin chromatography. Zonadhesin Zona binding protein containing mucin- like domains and prepro von Willebrand factor domains 82 . Rabbit Rabbit sperm antigens Family of intrinsic membrane glycoproteins with lectin-like zona binding activity, whose members share amino acid and carbohydrate similarities. Residues include xylose and sialic acid, with glucosamine as the only detectable amino sugar 83-85 .
Purified antigen blocks sperm-egg binding in humans.
Periodate Schiff positive. Binds Lens culinaris and Concanavalin A. also contains phosphorylatable tyrosines. Many zona pellucida binding proteins have been identified in the pig. A family of low molecular weight, sperm associated carbohydrate and zona binding proteins, the spermadhesins, have also been characterized. Members of this family include AWN-1, a broad specificity sperm surface lectin, which also contains soybean trypsin inhibitor and heparin binding sites.