Follow the path until you hits the Western Karanas zone. Be careful of the rabid gizzly's that sometimes happen upon the path. Western Karanas to Northern Karanas Ok, now the fun begins. The Karanas are a vast plain upon which some very nasty stuff hangs out. Once you enter this zone you have two choices, path or river.
Paths are extremely dangerous.
Lots of nasty things spawn near them, hang out on them, or cross them. However the river is on the edge of the zone and as you will see exploiting the edge is the best way to go. Head south to the river and turn left keeping the river on your right. Follow the edge of the river. This is where you can put your character on autorun and make a few minor course adjustments from time to time.