Although there is no precise scientific definition, we all know it when we have it. There are numerous changes in the balance of hormones, neurotransmitters and other biological substances in the body. This neurobiological imbalance leads not only to the symptoms described above, but also in a rapid heart rate and increased work load on the heart. The latter is responsible for increased cardiac mortality. There is a diffuse slowing of the brain waves as seen on EEG several hours 16 hours after all alcohol has cleared the body.
Neuromuscular performance is also impaired long after alcohol is undetectable in blood.
Socioeconomic Consequences Alcohol hangovers are not just a nuisance, and their socio-economic impact is not insignificant. Contrary to popular misconception, light to moderate drinkers account for the most work related costs. Causes of Hangover Hangovers are a poorly understood clinical entity despite their existence since ancient times. Scientists now believe the cause is multi-factorial and their occurrence is not solely related to the amount of alcohol consumed. Other factors include empty stomach, lack of sleep, psychosocial factors, increased physical activity while drinking, and dehydration.