Causes of Lupus Lupus is a complex disease whose cause is unknown. It is likely that there is no single cause but rather a combination of genetic, environmental, and possibly hormonal factors that work together to cause the disease. The exact cause may differ from one person to another. Scientists are making progress in understanding the causes of lupus. Instead, it appears that several genes may increase a person's susceptibility to the disease.
Much research is underway to discover the cause and a cure.
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