Don't spill it on healthy areas. I have a large yard in a mobile home park that is most unusual. What concerns me are three mulberry trees close to the front of the home and another in the back yard. One has roots very close to the home. They have grown considerably.
Roots are a problem if they are visible near the house foundation or have invaded the sewer lines.
When the trees receive deep, infrequent watering, surface roots may not be a problem. Large leathery leaves may eventually mold if left lying on the lawn or ground. Consult an allergist to determine if the mold could contribute to allergies. Before relocating them, they produced roses. Since then, neither has produced any roses.