Bile ducts contain neutrophils and are surrounded by edema. There is degeneration and necrosis of adjacent hepatocytes. Nephritis, lymphoplasmacytic, multifocal, mild. Cholangiohepatitis, neutrophilic, diffuse, mild. Gross Images 40x obj Case 21-2 .
Neurons contain granular brown perinuclear pigment.
Case 21-3 . There is diffuse centrilobular to submassive hepatocellular necrosis. Case 21-3 . There is proliferation of periportal fibroblasts and bile duct epithelial cells, with adjacent necrotic hepatocytes. Necrosis, centrilobular to submassive, with hemorrhage and intrahistiocytic light greenish-brown pigment.