One recognized aggregation, or cluster, of risk factors is commonly linked to Type 2 diabetes and CVD in adults.
Obesity is thought by some to also be a part of the syndrome.
At this time, little is known about the prevalence or development of the insulin resistance syndrome during childhood and adolescence. In addition, no studies have examined insulin resistance in youth with regard to eating habits, physical activity and maturational level, all of which can affect various risk factors, particularly those in the insulin resistance syndrome. CVD risk factors as well as aggregation of specific factors into the insulin resistance syndrome will be studied. Y outh in three cohorts, aged 8 - 18, will be evaluated annually for risk factors of CVD for 4 years or until they graduate from high school. We will also store all blood for possible future genetic studies as well as gather data from parents on the family history of CVD and their personal health habits.