It is dependent upon the amount and kind of radiation used, total dose administered, and field size and fractionation. In patients with osteoradionecrosis involving the mandible or facial bones, surgical debridement may be disfiguring, and reconstruction efforts may be futile unless tissue oxygenation is improved prior to surgery. Oral toxicity of chemotherapeutic agents. Periodontal infection in patients with acute nonlymphocytic leukemia. Stomatotoxic manifestations of cancer chemotherapy.
Mouth care for mucositis due to radiation therapy.
Jansma J, Vissink A, Bouma J, et al. A survey of prevention and treatment regimens for oral sequelae resulting from head and neck radiotherapy used in Dutch radiotherapy institutes. Description and incidence of oral complications. A new concept in the treatment of osteoradionecrosis. Hyperbaric oxygen as an adjunct in the treatment of osteoradionecrosis of the mandible.