These are known as the ectoderm , endoderm , and mesoderm . Derivatives of Mesoderm Mesenchyme is replaced by bone via intramembranous ossification . In fact there is very little difference between the two modes of bone formation. The stages of deposition are similar, with the removal of the cartilage model being the distinctive feature of endochondral ossification. Return to the Lecture Outline .
Modulation is a reversible form of cell division.
Osteoclasts have an active role in bone resorption and are not a product of resorption. These multinucleated cells are believed to be formed by the fusion of blood monocytes. This is an example of differentiation. Refer to any histology or anatomy textbook to view an illustration of endochondral ossification of a generic long bone. Note particularly that the process depicted in a single diagram summarises a 20-odd year process.