To make God's agenda your sole priority you've got to forsake your own. Abram and Sarai left what they knew for the unknown. The promise of land, a new place to call home. The promise of many descendants. The promise God would use them to benefit humankind.
Place is important.
Life takes place in a place. We are who we are due to where we've lived and where we're living. But a place, a land, is a means to an end, not an end in itself. It is possible for us to worship the land rather than the God who gave it. When that happens, instead of its flowing with milk and honey, it flows with blood.