This includes specification of the target condition, the type of patients and clinical presentations for which the guidelines are intended, and the interventions to be considered. The panel needs to also consider the setting for which the guidelines are intended, including types of providers and practice settings. This should be the principal analytic task in developing guidelines. The two principal sources of information are scientific evidence and expert opinion. The comprehensiveness of literature reviews varies in guideline development.
Panels can limit evidence to published studies or can include unpublished evidence.
Published evidence can be limited to clinical trials or can include other types of studies. Retrieval This includes literature searches, etc. This involves combining evidence from different studies to reach conclusions about the overall weight of the evidence of a particular topic. This can involve informal as well as formal analytic approaches. This involves combining evidence from different studies to reach conclusions about the overall weight of the evidence of a particular topic.