In addition, patients should receive routine pediatric care, including immunizations. Perform ongoing evaluations for the development of valvular cardiac disease. Such evaluations include annual echocardiograms. Many patients have evidence for obstructive airway disease. Conduct ongoing assessments for the development of clinically significant hypoventilation.
Patients typically have contractures and hand deformities.
A program of physical therapy may be beneficial in maintaining optimal function. Patients who develop clinically significant valvular heart disease may require valve replacement. Those with obstructive airway disease sometimes benefit from tonsillectomy and adenoidectomy. Corneal transplants have been successful in restoring vision to those with corneal clouding, though storage in the transplanted cornea will recur over time. Refer all patients suspected of having an MPS to a medical geneticist.