It may also increase your risk of having seizures. Use caution when driving, operating machinery, or performing other hazardous activities. Divalproex sodium may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities. Avoid smoking cigarettes and using other tobacco products.
Nicotine decreases the effectiveness of divalproex sodium.
Other, less serious side effects may be more likely to occur. Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. Other drugs used to treat seizures may increase or decrease the effects of divalproex sodium and may themselves have increased or decreased effectiveness. Tell your doctor about any other medications that you are taking.