Severe adenomyosis, diffuse and often deeper than 10 mm, resulted in therapeutic failures of endometrial ablation. Contemporary Use of GnRHa and Endometriosis Dr. Andre LeMay presented the consensus on ovarian suppression for endometriosis. Oral contraceptives are less effective. The efficacy of ovarian suppression before and after surgery for pain has not been established. The recurrence rate is proportional to the severity of the disease and the symptom-free interval is related to the degree of estrogen suppression.
Oral contraceptives are less effective.
The efficacy of ovarian suppression before and after surgery for pain has not been established. The recurrence rate is proportional to the severity of the disease and the symptom-free interval is related to the degree of estrogen suppression. Dr. S.K. Agarwal presented the underlying basis for the estrogen threshold hypothesis, which is the premise that tissues differ in their sensitivity in estrogen. Since tissue responsiveness to estrogens may vary, it may well be possible to manage endometriosis with GnRH agonists and provide estrogen add-back therapy for conservation of bone mineral density. Dr. Debra Bush presented the New Zealand Endometriosis Foundation educational program on menstrual health and endometriosis for young women age 15 to 24.