Cocaine is known to affect the function of the adult dopaminergic system. However, little is known about the impact of cocaine on the development of the fetal nervous system. This project represents an extension of the core project into a research area concerned with the consequences of perinatal drug exposure. Developmental Brain Res. J. Pharmacology Exp.
Prenatal haloperidol reduces the number of active midbrain dopamine neurons in rat offspring.
Neurotoxicology and Teratology , in press. An electrophysiological evaluation of serotonergic dorsal raphe neurons in Maudsley rats, Life Sciences , in press. Society for Neuroscience, 25th Annual Meeting, San Diego, November, 1995. Ibotenic acid lesions of the ventral hippocampus increases the proportion of bursting midbrain dopamine neurons in the A10 area of the rat. Society for Neuroscience, 25th Annual Meeting, San Diego, November, 1995.