I'd go nuts if I had to do the same thing forever. I'd say the hardest thing is dealing with irate fans. The community is what makes a game like AC work, but as with any person, two people don't always see eye to eye. I find it very frustrating that people can speak to me, or twist my words around without consequence, but if I speak my feelings frankly regardless of disclaimer it must reflect on the company as whole. I'm really not one for pulling punches or restraining from saying what I think, so learning when not to respond has been a real challenge for me - but a good one for me to learn from.
People expect developers to be inhuman, but complain when they get an inhuman response.
I do a lot of work in the music industry still. Mainly with The Slip and the Miracle Orchestra, but sometimes with record companies or promotion agencies. I'm pretty much the same way in that industry as I am in this one, skipping from role to role as I see fit. I'm a business advisor, internet consultant, web master, or just another fan in the crowd. I go to around 100 or so concerts a year on average, and it's as much as a family get together as it is a show.