Effective contraception is required for women going on Accutane. Before starting Accutane, two pregnancy tests will be performed. If you choose to go on Accutane, either you must abstain from sex or you must use two methods of birth control, for example, the birth control pill plus condoms. The most common side-effect of Accutane is dryness. The lips, nasal membranes, eyes, and skin become very dry.
Nosebleeds occur when the nasal lining dries out.
For prevention, you may coat nasal surfaces with petrolatum or Aquaphor. The backs of the hands frequently develop a minor rash that can be controlled with hydrocortisone ointment. Your skin will be more sensitive to sunlight so sunblock is necessary. Many patients experience minor eye irritation, contact lens intolerance, and occasional pink eye infections that may require medical attention. In a few cases, dry eyes have been a real problem.