Cytologic examination of the vitreous specimen was negative for malignant cells. These four reports all describe a condition with fundus lesions that mimics POHS but with the addition of vitritis and, often , an anterior uveitis. The ages have varied from 6 to 69 years, but most patients are in their thirties. There appears to be no racial predilection. Most patients give no history of living in areas endemic for POHS nor do they have affected family members.
Patients usually present subacutely with decreased central vision or metamorphpsia.
Other less common presenting complaints include paracentral scotomata, floaters, photopsias, mild ocular discomfort, and photophobia. In POHS, the anterior chamber is notably clear. Vitritis MCP differs from POHS clinically in a number of ways , the most important being the presence of vitritis in one or both eyes. The vitritis ranges from mild to moderate and may be asymmetrical. Little vitreous debris is seen once the active inflammation quiets down.