In fluorescein angiography acute lesions hyperfluoresce early and leak lately. Old scars typically act as window defects with early hyperfluorescence and late fading. Visual field testing may reveal blind spot enlargement, scotomata corresponding to the chorioretinal lesions, or large temporal field defects which do not necessarily have corresponding fundus lesions. Clinical course MCP tends to be a chronic disorder lasting several months to years. Recurrent bouts of inflammation are the rule and may occur in one or both eyes, either separately or simultaneously.
New lesions can occur anywhere in the fundus.
CNVM's may be present initially or develop late in the follow-up. Because of the chronic and recurrent nature of MCP, patients need to be followed closely. The visual prognosis in MCP is guarded, mostly due to choroidal CNVM's which occur in about one third of the patients. The cause of MCP is not fully understood. Moreover, patients with MCP do not have systemic signs of chronic EBV infection.