C. the RFLP actually causes the gene defect. E. the entire DNA sequence of the disease gene is known. B. Allelic heterogeneity. C. Maximum likelihood analysis from Cajun study is inconclusive. D. Locus heterogeneity E. Double crossovers occur more frequently at the CMT locus.
Melanin biosynthesis requires a number of enzymatic reactions.
Two unrelated individuals with albinism marry and have four children all with normal pigmentation. The parents are homozygous recessive, but at different genetic loci. D. Albinism is a multifactorial disorder that is controlled by genetic and environmental factors. E. This type of albinism is dominant with incomplete penetrance. Type II restriction endonucleases are useful in subcloning because A. they cut double-stranded DNA at specific sites and the resulting fragments always have blunt ends.