The stronger the negative charge on a protein, the faster it migrates. The separated proteins appear as distinct bands. The most prominent of these and the one that moves closest to the positive electrode is serum albumin . Serum albumin is made in the liver binds many small molecules for transport through the blood helps maintain the osmotic pressure of the blood The other proteins are the various serum globulins. Gamma globulins are the least negatively-charged serum proteins.
Most antibodies are gamma globulins.
Therefore gamma globulins become more abundant following infections or immunizations. Discussion of the 5 classes of antibody molecules. Because such preparations of immune globulin contain antibodies against most common infectious diseases, the patient gains temporary protection against the disease. Because of their relationship to cardiovascular disease, the analysis of serum lipids has become an important health measure. A cardiac risk ratio greater than 7 is considered a warning.