In Canada it occurs mainly in Ontario. The main growing region used to be the Ohio Valley before it became victim to deforestation. In 1991 goldenseal was officially recognized as an endangered species, due to the fact that deforestation destroyed most of the Goldenseal's natural habitat. Other common names include seal-all, grand raspberry, golden thread, yellow root, Indian dye eye root and Jaundice root. Roots, stems, and leaves.
Many herbalists consider it one of the most powerful herbs.
It is one of the most effective remedies for inflamed and catarrhal conditions of the mucas mambranes. Recently, goldenseal has gained a reputation as a herbal antibiotic and immune system enhancer. Also, over use could result in nausea, vomiting, diarrhea, a sensation of burning skin, convulsion, respiratory failure, paralysis and death. However, it has not been scientifically studied yet to confirm this use.