Obviously this is an invasive procedure. Fortunately, Leptospira interrogans is sensitive to penicillin , a readily available antibiotic. After penicillin has been used to stop leptospire reproduction and limit bloodstream infection, tetracycline derivatives are used to clear leptospires from the kidneys. Intravenous fluids are crucial to support blood flow through the damaged kidneys so that recovery is possible. Any areas at home that have been contaminated with urine should be disinfected with an iodine based product and gloves should be warn in cleaning up any urine.
Prognosis is guarded depending on the extent of organ damage.
Dogs having moderate to severe elevations tended to receive hemodialysis. In short, dogs with the most severe renal toxin build up probably need referral to a critical care facility that supports hemodialysis. Obviously, there is some overlap. Vaccination options Vaccination against Leptospira interrogans is only available for the serovars called canicola, grippotyphosa, pomona and icterohaemorragiae. . As a result of long standing use of this vaccine, it is hard to assess how important it is to vaccinate against leptospirosis.