Homepage CBE Research Integration Tangibly connecting all projects together is the requirement for computational analysis, mathematical modeling, and scale-up of specific biofilm processes. In order for industry to begin to understand and ultimately control complex biological systems, a methodology is required for extrapolating phenomenological data obtained at the microscale to macroscale practice.
Models provide the framework for integration and synthesis.
Scientists and engineers from all Center research projects work in collaboration to create new, or to modify existing, conceptual models for biofilm processes. For each model, quantitative characteristics are associated with each model component, whenever quantification is possible. The conceptual model is converted into mathematical expressions, then into computer code. The models are evaluated by comparing model predictions to real data. The CAS group includes computer scientists, mathematicians, engineers, and statisticians, who provide technical assistance to Center researchers.