When growth is required, a complex series of reactions turns it on. So far, so good. With its three-dimensional structure now known, researchers can see how this happens. Diagrams published last month in the British scientific journal Nature , look like four crumpled curls of crepe tied together with string. Two of the curls, or lobes, are responsible for catalyzing growth.
More research needs to be done to determine how the switch stays on.
Keep in mind, this whole molecular machine is too small and quick-changing to be viewed in the most powerful microscope. The researchers had to crystallize the protein to hold it in one position. It's exciting and satisfying to see it finally. To enable the structure of other proteins and molecules on which life depends to be seen in the same way, the Medical School has created the Center for Structural Biology. It supports structural research in all parts of the University and its affiliated hospitals.