It acts just like the spellcheck on your computer. So this is the molecular equivalent of spellcheck. MDM2 is the net, and p53 is the globular form. There's no cell suicide, no arrest, no repair. Uncontrolled cell proliferation happens.
More mutations creep into the information, the situation gets worse and worse, and a cancer arises.
The p53 gene watches over us. These mutations are found in 55 percent of all human cancers. They get cancer at a very young age, just as we predicted they should, and there are multiple cancers in families. So that's the inherited form. But there is another way to inactivate p53 .