These lower life form organisms are mostly anaerobic. Doctors using the proper concentrations and correct medical protocols have achieved substantial positive clinical results with Ozone. If it wasn't safe to breathe acceptable concentrations of ozone, the military would not purify the air in our submarines with it. Other methods being explored medically are rectal insufflation, autohemotherapy, and IV infusion. When man dumps pollutants into the air, nature tries to repair the damage by sending ozone into the affected area to oxidize and clean them up.
Nature works through the balancing of differential electrical, magnetic, and chemical charges.
This explains why Ozone is always found near air pollution. Ozone is not irritating you in smog, it's the toxins like nitric acids formed that hurt people. But, because ozone is there, then the newscasters and scientists try to blame our troubles on our poor friend Ozone. By blaming nature, no one has to take responsibility for the car and factory emissions. No one ever has to develop clean energy sources.