Increasingly in recent years, scientists have recognized that some heart disease risk factors cluster together in certain people.
Many scientists think that it's genetically based.
The underlying cause isn't fully understood. People with Syndrome X are at increased risk of coronary artery disease. Syndrome X has been observed in people who are insulin-resistant. One such group is people with diabetes , who have a defect in insulin action and can't maintain a proper level of glucose in their blood. This condition is known as hyperinsulinemia .