Symptoms can include a red, itchy rash that may manifest as vesicles or blisters on the skin beginning 24-48 hours after contact. The condition can become chronic through repeated exposure. Type I hypersensitivity, also called latex allergy, is the most serious latex reaction. It results from exposure to latex proteins. The amount of exposure needed to cause this reaction is unknown.
Reactions usually begin within minutes of exposure, but can occur hours later.
Symptoms vary from mild to severe. Mild symptoms include skin redness, hives, and itching. Severe reactions may involve respiratory symptoms such as runny nose, sneezing, itchy eyes, scratchy throat, asthma and, in rare cases, shock. I hypersensitivity can occur through exposure to airborne allergens via the respiratory route. Latex proteins adhere to powder particles and become aerosolized during glove removal.