Extralymphatic disease presents confusing problems in staging. For example, a patient with disease in the chest and neck, with systemic symptoms, and a negative lymphangiogram, might be found at laparotomy to have involvement of the spleen, liver, and bone marrow. Dudgeon DL, Kelly R, Ghory MJ, et al. The efficacy of lymphangiography in the staging of pediatric Hodgkin's disease. Azizkhan RG, Dudgeon DL, Buck JR, et al.
Pulmonary function is compromised in children with mediastinal lymphoma.
Prospective evaluation by computed tomography and pulmonary function tests of children with mediastinal masses. Mediastinal mass and tracheal obstruction during general anesthesia. Management of stage I-II Hodgkin's disease in children. Hays DM, Fryer CJ, Pringle KC, et al. Hays DM, Ternberg JL, Chen TT, et al.