My overall interest is in the field of General Pathology. Since 1973, when I joined UMass, I have been collaborating with Drs. More specifically, we have worked on mechanisms of microvascular leakage in inflammation, on arterial changes in spasm, on the pathogenesis of atherosclerosis, on the role of shear stress in intimal damage, and related topics. I am generally interested in the pathophysiology of inflammation, in the structure and function of myofibroblasts, and in cell injury and cell death.
Medical history is another major focus.