Trying it Crystallographers seem to be rather conservative when it comes to changing the way things are done. E.g. they favour hanging drops vs. sitting drops etc. In cubo crystallization is a completely different world altogether. Newcomers may find it easier to deal with the problems you encounter when playing around with sticky materials, using solid salts as crystallants and mixing their precious membrane protein prep. This is clearly an issue of psychology.
Protein crystals form inside a lipid crystal.
That's pretty far out. You can grow crystals of membrane proteins that have never seen any detergent. Once crystals are grown you may need to remove them from the embedding matrix, the cubic phase for your experiment. In cases where the surrounding lipid does not interfere, you can rip out the crystal with a little tool. But there are cases where it is absolutely necessary to remove the lipid from the crystal.