If this is not your name, click here. Other Ophthalmic Surgery Organ Transplantation Orthopaedics Other Osteoarthritis Osteoporosis Otitis Otorhino. In both groups, patients were also allowed to receive standard treatment recommended for the management of cystic fibrosis, which may have included oral or intravenous antibiotics. Tobi has shown us that inhaled antibiotics work and that has tremendous implications for future treatment of cystic fibrosis.
Pulmonary function is the best predictor of disease progression in people with cystic fibrosis.
Tobi patients also were 36 percent less likely to require intravenous antipseudomonal antibiotics than patients taking placebo. Overall adverse events were comparable but less severe in the Tobi group than in the placebo group. It was transient and appeared mild or moderate in severity. Four patients in the placebo group and none in the Tobi group died during the studies. Additional data showed greatest benefit in teenagers and females.