The abnormalities include disorders of growth and mental development, dysmorphic facies, and osteoarticular, cardiovascular, and other anomalies.
Neoplasms complicate some cases.
Microcephaly, brachycephaly, midfacial hypoplasia, wide fontanels, metopic ridging, and mild micrognathia. Umbilical or inguinal hernia. Dermatoglyphic abnormalities consist of abnormal palmar creases. Neuroblastoma, mesenchymoma, and Wilms tumor have been reported in some infants.