Signs develop between four and ten months of age, although the disease may the may be subclinical. The pattern of lameness depends on the joint that is affected and whether the problem is unilateral or bilateral. Joints in both the fore- and hind limbs may be involved. Dogs with mild clinical signs may show only stiffness on rising that improves with exercise. The dog may adopt a characteristic posture, i.e. extended hocks, if these joints are involved, or there may be external rotation of the front feet if the elbows are affected.
Pain is present in manipulation, usually extension of the affected joint.
Pain may be elicited by direct pressure over the affected area of the joint, i.e. shoulder joint. There may be swelling of the affected joint and loss of muscle size if the affected leg. Treatment of affected joints may be surgical or conservative. The optimum treatment for some joints remains controversial. Nutriceuticals are also warranted i.e. glucosamines, MSM, and omega 3 fatty acids.