There are many excellent anti-spam resources, and I've placed their URLs at the end of this page. This is what I'm doing as of May 2001. I use SpamCop for my public email addresses, and I route my older email addresses to it. I use spam filters in my Eudora email package. In particular, I now use positive filtering .
Potential spam goes into a spam box for rapid deletion.
This is the one approach that really seems to work. The secret is to have at least two email addresses. The other is your private, unlisted , address. Ideally your unlisted address is one you intend to keep for life. The best choice, I think, is a college or university alumni email address.