No abnormalities developed in the laboratory tests that were monitored. All six patients experienced clinical improvement. Five went into clinical remission. This included reduction in diarrhea, abdominal pain and improved energy level. The improvement lasted five weeks to several months suggesting that additional doses might be necessary to prolong the response.
Preliminary results suggest that additional doses can be effective in prolonging the benefit.
The initial results are very encouraging, but additional clinical studies are required to establish this approach as being safe and effective. In summary, it is possible that failure to experience colonization with helminths predisposes to immune imbalance, which can lead to development of inflammatory bowel diseases and other Th1-type inflammatory conditions like multiple sclerosis and type 1 juvenile diabetes. Related articles for further reading 1. Inflammatory bowel and celiac disease. The Autoimmune Diseases, Third Edition.