Please conduct a current literature search and check the appropriate current online database for the most recent quantitative information.
Mixed cresols are also strong dermal irritants.
EPA estimates that consumption of this dose or less, over a lifetime, would not likely result in the occurrence of chronic noncancer effects. Animal studies have reported developmental effects, but only at maternally toxic doses, and no reproductive effects from oral exposure to mixed cresols. Only anecdotal information is available on the carcinogenic effects of mixed cresols in humans. Exceedance of the RfD does not imply that an adverse health effect would necessarily occur. As the amount and frequency of exposures exceeding the RfD increase, the probability of adverse health effects also increases.