It is not commonly used as a treatment for hirsutism. If the patient s major complaint is menstrual irregularity, then this can be managed by the use of progestins. Provera can be given is a dose of 5-10mgs for ten days every month. This will result in cyclic shedding of the endometrium and a reduction in the incidences of endometrial hyperplasia and adenocarcinoma. If the patient is young and taking Provera she would require another contraceptive agents such as a barrier method.
Oral contraceptives are also an excellent choice.
Finally, Glucophage may result in cycle regularity. If the patient does not wish to conceive and is taking Glucophage, she would require barrier contraception. PCOS is associated with an increase in serum triglycerides, LDL, and VLDL cholesterol. Because of obesity, dyslipidemia and insulin resistance, patients with PCOS have increased risk factors for hypertension, coronary artery disease and diabetes mellitus. Clearly there is an observed increased incidence of hypertension and diabetes.