Subcortical dementias - Depression tends to be part of the total symptom picture, with mood alteration not solely situational and more likely to be persistant. May respond to standard interventions. Depression likely to exacerbate cognitive deficits. Often insight is preserved, so that the patient is aware of their impairment. Depression likely to exacerbate cognitive deficits.
Most cases occur in later life, with few reports in early or midlife.
A Clinical Approach . Cummings, J.L., Ed. Subcortical Dementia . Oxford University Press. Aging and Neuropsychological Assessment .