Reactive lymphocytes exhibit variable size and shape.
These cells have a round to ovoid appearance and range in size from 10 to 25 m in diameter. Platelets are blue-gray fragments of megakaryocytic cytoplasm which contain azurophilic granules and range in size from 1.5 to 3 microns in diameter. S zary cell is the preferred choice based on the clinical history and the morphologic features. S zary cells have a characteristic cerebriform, grooved or folded nucleus. The chromatin pattern is hyperchromatic with inapparent nucleoli.