An alternative is natural progesterone. Only certain full service pharmacies are capable of providing this type of progesterone. Estrogen, alone, may increase a women's risk of endometrial cancer. Progestin Taken with Estrogen Reduces Risk of Endometrial Cancer. Progestin is almost always prescribed as part of hormone replacement therapy.
Progestin helps prepare the lining of the uterus for a potentially fertilized egg.
Women who take both progestin and estrogen have a lower risk of endometrial cancer than those women who take no hormones. Some women will not want to take hormone replacement therapy due to medical contraindications, side effects, or a desire not to take medication for a natural life cycle phase. The data supporting these claims is still in its early stage and further research is needed to measure the benefits. Dietary Sources of Phytoestrogens Soy Soy is a rich source of phytoestrogens. These are small seeds similar in appearance to sesame seeds.