The complex nature of tumorigenesis, which may be controlled by multiple genetic defects, probably will not be halted by altering a single gene. Also, as of yet, a systematic method to administer the normal p53 gene is not possible, and many patients succumb to distant metastases. The role of gene therapy in head and neck cancer is important, however, to improve our understanding of this disease and to make progress toward an effective treatment in the future. Interstitial iodine 125 in advanced recurrent squamous cell carcinoma of the head and neck with follow-up evaluation of carotid artery by ultrasound. Medicine is a constantly changing science and not all therapies are clearly established.
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