In most cases, surgical excision of the primary tumour will be combined with a neck dissection. The majority of laryngeal tumours are squamous cell carcinomas. Rare tumours include minor salivary gland tumours, sarcoma and plasmacytoma. 10.1 Hyperkeratosis of the Vocal Cords Hyperkeratosis of the vocal cords should be viewed with the gravest of suspicion and all of these patients should have repeat microlaryngoscopy and excision if any abnormality persists. Simple biopsy reports may be misleading if the examination has not been sufficiently thorough.
Many dysplastic lesions progress to malignancy.
All involved physicians must be aware of the high incidence of multicentric lesions and of co-existing invasive carcinoma in the larynx of these patients. Radiation therapy is the treatment of choice for this condition. The patient has stopped smoking. There is no possibility that the patient will be lost to follow-up. Bilateral in situ disease is an absolute indication for radiation treatment.