Some features of this syndrome are similar to those in Bloom and fetal alcohol syndromes. Microcephaly, micrognathia, prognathism triangular face, high sloping forehead, craniosynostosis, narrow bifrontal diameter, dolichocephaly, trigonocephaly, small face and narrow face, brachycephaly, large open fontanels, prominent occiput, prominent glabella, flat occiput, and Robin sequence.
Otitis media is frequent.
Blepharophimosis, blepharoptosis, telecanthus, hypertelorism or hypotelorism, upslanted or downslanted palpebral fissures, epicanthus, arched eyebrows, strabismus, esotropia, microphthalmia, iris coloboma, nystagmus, anisocoria, megalocornea, iris hypoplasia, oculomotor paralysis, astigmatism, blue sclera, deep optic nerve cupping, immature retinal vessels, and tortuosity of retinal vessels. Dental abnormalities, include delayed eruption, dental caries, crowded teeth, microdontia, malocclusion, malaligned teeth, diastema, conical teeth, oligodontia, macrodontia, fused teeth, doubled teeth, bifid incisors, and rotated lower incisors. Pectus excavatum, pectus carinatum, rib synostosis, and accessory nipples. Foot abnormalities include small feet, syndactyly, pes valgus, pes equinovalgus, pes planus, broad first toes, overlapping toes, diastasis of 1st and 2nd toes, short toes, wide 2nd toes, short metatarsal bones, metatarsus varus, and adducted metatarsal bones. Dermatoglyphic findings include preponderance of ulnar loops, abnormal flexor creases, interdigital loops, distal axial triradius, hypothenar pattern, preponderance of whorls, absence of c triradius, ridge dysplasia, low total ridge count, and tibial loops in hallucal areas.