Triggers production of local prostaglandins that promote vascular changes that cause follicle to swell, increases secretion of digestive enzymes which digest away intercellular materials of follicle wall 4. Causes luteinization of theca and granulosa cells following ovulation. This causes both FSH and LH surges just before ovulation. LH surge lasts for only one to two days Gradual rise in estrogen in early antral stages of follicle growth inhibit LH secretion. Secreted by follicles into antral fluid, and blood.
Most estrone is formed in peripheral tissue from androgens secreted by ad.
Estriol is primarily from metabolism of estradiol and estrone in liver. The 12 plus follicles that start to develop each month during the reproductive years of the female are a critical and necessary source of estrogens. Thus it forms a fern- like pattern when spread on a glass slide. This is particularly true when LH is present. Only minute amounts of estrogens secreted during childhood See Guyton, page 1024 for comments on intracellular processes.