With hand-printing processes such as manual screenprinting or manual lithography, a much smaller quantity of prints are made, usually no more than 100. Limited editions are usually signed but always numbered. Open editions are not limited, as many are printed as people want to buy. Obviously, limited editions generally command higher prices. Same as with the prints, above.
Original sculptures are hand-made out of clay, etc.
With the reproductions, the original is used to make a mould which is them used to make copies of the original. Again, reproductions of sculptures can be limited or open editions, just like with prints. By skilled, pipe-smoking craftsmen using some of the most sophisticated computational apparatus in the British Empire. Equipment similar to this was used to create this outstanding website.