Like alcoholic drinks, you should also avoid mixing your medications. Painkillers, cold remedies and antihistamines are probably the most frequently misused drugs. Painkillers Pain is a symptom, not an illness - if it persists, you need a diagnosis from a doctor. Try rest for headaches, gentle exercise for backache and a hot water bottle for period pains. Don't exceed the dose - it can cause ringing in the ears and stomach pain.
Many people find it upsets their stomachs anyway.
Don't take it with alcohol, which makes it even more irritating to the stomach. Don't take it five days before an operation because it can increase bleeding. People often exceed the dose, which is only eight tablets of 500mg a day. Overdose causes liver damage and has occurred with 10 tablets. Some people mix it with caffeine to treat headaches which can either work or make it worse - it's an individual thing.