You and your doctor should consider your T-cell count, your viral load, any symptoms you are having, and your attitude about taking HIV medications. Some mutations can keep multiplying even when you are taking an antiviral drug. When this happens, the drug will stop working. However, when you take more than one antiviral drug at the same time, HIV mutates much more slowly and it takes much longer for resistance to develop. Sometimes, if you develop resistance to one drug, you will also have resistance to other antiviral drugs.
Resistance can develop quickly.
The recommended dose of delavirdine for adults is 400 mg three times a day. This would be a daily total of 6 of the 200 mg pills, or 12 of the 100 mg pills. Delavirdine can be taken with or without food. These side effects usually get better or disappear over time. The most common side effect of delavirdine is a skin rash, which develops in about 25 percent of people taking the drug.