These multivitamin preparations are designed to help prevent disease and to supplement the diet in cases of unusual stress and other such situations. Therapeutic multivitamin preparations are prescribed by physicians only for deficiency states and for the nutritional support of severe pathological conditions. Magnesium is an essential element in human metabolism and functions in the activities of muscles and nerves, protein synthesis, and many other reactions. Magnesium deficiency may occur in alcoholism, diabetes mellitus, pancreatitis, and renal diseases.
Prolonged deficiency can cause changes in heart and skeletal muscle.
Excessive retention of magnesium can occur in renal disease and results in muscle weakness and hypertension. The only established use of riboflavin is in the therapy or prevention of deficiency disease.