These can have a positive or negative effect. Stress, 'mid-life crisis' and 'sandwich generation' issues can decrease a woman's interest in sex simply by being the distractions that they are. Feelings of loss of attractiveness due to aging can also affect the sex drive negatively. The Good News On the positive side, as women pass through their forties, as they approach menopause, often feel more free sexually. This may be because women worried about the risk of pregnancy in earlier years, and now that the risk is diminishing, they enjoy sex more.
Many women have surges of hormones and thus are more interested in sex at various times.
Also, don't forget that your partner of a similar age is getting older, too. There is still a tendency for women to consider themselves and be considered by their partner to be the cause of decreased frequency of sex. Both men and women will take longer to reach orgasm, and longer in between orgasms. If both partners accept this fact and change their sexual repertoire to accommodate it, sex can be enjoyed throughout this decade of life, and for many more decades beyond.