Unfortunately, they'll only drain your energy, keep you helpless, and affect your ability to think clearly. Try to drink or use only in moderation or avoid substances altogether. Relax and play. Relieving stress can improve your ability to communicate and make decisions. Physical activity can increase your sense of well-being.
Regular exercise done with others can be fun, too.
Try to eat well. Your physical health affects the way you feel as well as your ability to cope with stress. Save money and get some job skills. Knowing you have an emergency fund can help reduce your anxiety. If you have job skills, it'll be easier to avoid depending on others to get by.