The pulmonic valve separates the right ventricle from the pulmonary artery. With pulmonic stenosis there is increased pressure in the right ventricle. With pulmonic regurgitation there is volume overload of the right ventricle. Either way, the right ventricle can ultimately fail. The mitral valve separates the left atrium from the left ventricle.
Mitral stenosis causes damming up of blood in the left atrium, and ultimately in the lungs.
Mitral regurgitation causes dilation of both the left atrium and left ventricle, and can lead to failure of both cardiac chambers. MVP often involves at least mild regurgitation. Click here for a complete discussion of MVP . The aortic valve The aortic valve separates the left ventricle from the aorta. Aortic stenosis causes increased pressure in the left ventricle.