Granular WBC come from red bone marrow and contain cytoplasmic granules. They have lobed nuclei and include neutrophils , eosinophils and basophils. Neutrophils have the greatest activity following bacterially destroyed tissue. Their primary role is phagocytosis. High neutrophil counts suggest damage due to invading bacteria.
Neutrophils have salmon pink granules and multi-lobulated nuclei.
Eosinophils in large numbers suggest allergic conditions. They are believed to combat allergens, which cause allergies. They are elevated also in cases of pork worm infection, psoriasis, Hodgkin's disease and some cancers. Numbers decrease after periods of stress. Eosinophils are about the same size as neutrophils, but have reddish-orange granules.