An inheritable disorder characterized by skin lesions , varying degrees of mental retardation , and seizures . Tuberous sclerosis is inherited as an autosomal dominant trait. The disease is named after the typical brain lesion which is called a tuber. Later seizures tend to be myoclonic.
Mental retardation becomes evident as infants begin to miss their normal developmental milestones .
Several different skin lesions are common in tuberous sclerosis. Prevention Genetic counseling is recommended for prospective parents with a family history of tuberous sclerosis. Prenatal diagnosis is not yet available. Tuberous sclerosis can appear as a new mutation. These cases are not preventable.