Platelets are discoid cells of the blood.
Large platelets appear to be associated with increased platelet coagulability and increased risk of heart attack and stroke. However the reliability of MPV measurement is yet to be established. Blood samples analysed at the time of venipuncture give more reliable MPV measurements then when blood analyses are delayed. In this talk two models for extrapolating MPV to the time of venipuncture will be presented. For the first model, MPV was modeled as a function of the logarithmic transformed time until the blood analysis using a linear least square approach.