Lymph node Extranodal lymphoid tissue, eg gut, submucosa, skin Rarely begins in unusual site such as brain Lymphomas spread to adjacent nodes, liver, spleen and eventually organ. Rx because of ability to control overt and occult metastases. Clinical presentation asymptomatic renal mass or hematuria. Metastases most likely to lung. Radiotherapy very rarely used.
Prognosis depends on histology, site of disease and staging.
Autologous bone marrow transplantation for recurrent disease now being tried.