A 30 year old female has sudden onset of fever, abdominal pain, tachycardia, nausea, and jaundice. She is anemic, with Hgb 11.1, Hct 28.8, and MCV 77. The WBC count is normal, and she has marked reticulocytosis. RBC morphology shows small cells that lack central pallor.
Physical examination reveals a palpable spleen tip.