Binding of NT to receptors lead to opening or closing of ion channels in the post-synaptic neuron. The resulting ion fluxes change the memb. There are two major classes of NT receptors, ionotropic and metabotropic receptors.
Receptor molecule is also an ion channel.
Fast post-synaptic responses. Responses last only for a few milliseconds. Also called Ligand-gated ion channels E.g. Each subunit crosses the memb. The second transmemb.