I really don t want to wait that long without the protection. It is remotely possible that vitamin E was the cause of the swelling in your lower leg. I agree with you that vitamin E has many positive benefits for diabetes patients, and that you should be getting daily supplements of it. The only way we will know is to have you start taking vitamin E again to see if the swelling and blisters return. I would start with a vitamin E dose of 200 mg. to see what happens.
Many people take much larger doses of vitamin E without problems.
I hope that the vitamin E is not the cause of your problems. A weight loss of 10 percent is a cause for concern if it was unintentional and undesirable. I would use your height to determine a healthy body weight for yourself. Weight loss becomes dangerous if your weight drops below the ideal. You are losing weight, in part, because of your high blood sugars.