Risks, Possible Side Effects or Adverse Reactions HRT is generally well tolerated. The most common undesirable side effect is abnormal uterine bleeding, which usually diminishes in time. Notify your doctor if it does occur. Swollen feet or legs. Breast tenderness or pain.
Medical studies indicate no increased risk of breast cancer with hormone replacement therapy.
The usual dosages of hormone replacement therapy for menopausal symptoms are kept low and less likely to cause side effects or adverse reactions as are the higher doses used in oral contraceptives or used to treat some cancers. Follow-Up Examinations Women taking hormones should have an annual pelvic examination including a Pap smear test, and a mammogram. If You or a family member has symptoms of menopause and is interested in hormone replacement therapy. Following treatment, unexpected side effects occur. Any of the symptoms of a blood clot occur.