Your high school performance is what gains you admission to the college of your choice, but from the day you enter college you must begin to build your resume all over again. This resume building continues until the day you graduate. It is up to you to build that record. Internships may be done at any time. It depends on your needs and the needs of the the employer.
Opportunities are always available.
What opportunities might fit your needs depends on your major, skills, financial needs, personal desires, and where you are willing to go. Positions can be found worldwide. While some internships may be available only to sophomores and above, there are also plenty of opportunities for second semester freshmen. Internships are truly a case where the more the better. Please read it.