As with other anticonvulsants, psychosis has rarely been reported as a side-effect. Only a few interactions between topiramate and other drugs have been identified. Topiramate may lead to decreased effectiveness of some oral anticontraceptives. Alcohol may increase the severity of the side-effects of topiramate. The FDA has recently approved the use of topiramate in children.
Older people seem to handle topiramate similarly to younger ones.
There is little experience using topiramate for the treatment of psychiatric disorders in the elderly. There are no specific symptoms that have been described following the abrupt discontinuation of topiramate, other than the seizures that sometimes follow the rapid discontinuation of any anticonvulsant. Only when necessary because of a serious side effect, should topiramate be suddenly discontinued. There is only limited data on the effects of overdoses of topiramate. There have been no reports of deaths following an overdose.