Sera from ALS patients has not been tested previously on the calcium currents in motoneurons. We are using isolated rat motoneurons in culture with whole cell patch clamp recording to investigate any possible effects of ALS serum on the voltage dependent calcium channels. Adenosine acting at an A1 receptor decreases N-type calcium current in mouse motoneurons. Identification of different putative neuronal subtypes in hippocampus using electrophysiological parameters. Hogan, Q.H., J.B. McCallum, C. Sarantopoulos, M. Aason, M. Mynlieff, W-M. Kwok and Z.J. Bosnjak.
Painful neuropathy decreases membrane calcium current in mammalian primary afferent neurons.
Carter, T.J. and M. Mynlieff. Effect of GABA-B receptor activation on calcium channels in putatively identified neuronal subtypes of the hippocampus. 26 th Annual Society for Neuroscience Meeting, November, 2000. Schmidt, J.R. and M. Mynlieff. Effect of antibodies isolated from sporadic ALS patients on voltage-dependant calcium currents in dissociated rat motor neurons.