Development of the Major Pathways for Neurite Outgrowth in the Chick Hindlimb . The pattern of motoneuron outgrowth is dictated by pathways that allow for growth cone advancement. It was found that neurite-neurite interactions were the predominant contacts that help direct neurite pattern formation. Growth is also controlled by interactions between the neurites and their environment. Areas of high cell packing density greatly define neurite outgrowth.
Neurons prefer to grow in lower cell density areas.
These areas allow growth cone advancement. These areas also dictate neurite outgrowth patterns. Muscle Sensory Innervation Patterns in Embryonic Chick Hindlimbs Following Dorsal Root Ganglion Reversal . Sensory neurons grow along with the motoneurons for that area, but they travel a little behind the motoneurons. The rostrocaudal order of dorsal root ganglions were reversed by rotating the neural crest.