For all the loyalty the independents offer their acts, the simple fact is that most can only afford to lose so much money before they have to close the doors. There is hope, however. Most of the current batch of indies seem to be in it for the long haul. If not profitable, they are at least breaking even, which opens the door for future releases. My long term goals are just to try my hardest to keep the label going, and it's hard, that's for sure.
Nobody can say for sure.
But they're here now, and they're putting out some of the best music on the market. It may take a bit of effort to find them, but it's time and energy well spent.