In two days, he would be depressed and lose his appetite. By three days, he would probably not be able to get up. There may be additional symptoms such as trembling, hyperactivity, increased water consumption and urination, and diarrhea. There are several other diseases that can cause these same, or very similar, symptoms. Laboratory tests are needed to rule these out, and help confirm the diagnosis.
Prompt treatment is critical.
In one dog, treatment was begun within30 minutes, and in another, within 8 hours, and both survived. The second dog required a much longer and more expensive course of treatment. A third dog was not seen until 3 days after ingesting calcipotriene and that dog died in spite of treatment. Treatment involves first making the dog vomit to get rid of anything remaining in the stomach. Then large doses of activated charcoal and a laxative are given by stomach tube.