The most frequently reported side effects for both Denavir and placebo were headache and mild skin irritation. Denavir should be initiated at the first symptom, such as tingling, or first sign, such as swelling. It is the first topical antiviral treatment to convincingly affect the clinical course of recurrent cold sores. After 25 years of research into the management of cold sores, now there is a product that clearly impacts this disease. Cold sores affect an estimated 40 million Americans each year with a rate of frequency which varies from rare episodes to 12 or more recurrences per year.
Most sufferers experience one to three attacks annually.
Cold sores generally appear around the mouth and on the lips. The signs and symptoms of cold sores usually begin with tingling discomfort or itching leading to lesions which eventually rupture and then begin to dry, forming a thin yellowish crust. Healing of the blisters is usually complete by 8 to 10 days after onset if untreated. Any question regarding a medical diagnosis, treatment, referral, drug availability or pricing should be directed to either a licensed physician or to the product's manufacturer.