This information is often buried within the paper. Databases generally keyword search for words or phrases in the title, abstract, or descriptor. The painful procedures are sometimes, but not often, mentioned in those categories. Therefore, a broader view is needed to see if the study's ultimate objectives can be met with alternative methods. Beside the legal aspect, there are many other benefits of the alternatives search.
Many researchers run literature searches when designing a study.
Such searches can easily be tailored to address alternatives. It may provide more meaningful data by avoiding confounding factors in the experimental design such as distress in the animal model. Hopefully, with a little patience and understanding, researchers will see the alternatives search as a valuable tool for improving the quality of research and not a dreaded Federal mandate. The Principles of Humane Experimental Technique . AWIC tips for searching for alternatives to animal research and testing.