Windows in the lab are sealed. An autoclave is preferably available within the lab. A ducted air ventilation system that directs airflow into the lab through the entry area is provided. The exhaust air is not recirculated to any other area of the building. A logbook signed by all personnel indicates the date and time of entry and exit.
Personnel enter and leave the facility only through clothing change and shower rooms.
A system is set up for reporting lab accidents or illnesses. Biological materials to be removed from class III cabinets in a viable or intact state are transferred to a nonbreakable, sealed primary container and then enclosed in a nonbreakable, sealed secondary container that is removed from the facility through a disinfectant dunk tank, fumigation chamber, or an airlock designed for this purpose. No non-viable materials are to be removed unless they first have been autoclaved or decontaminated. Supplies and materials are brought in by way of double-doored autoclave, fumigation chamber, or airlock. Walls, floors, and ceilings of the facility are sealed.