You want your publication to be easy to read and look professional. Most books use a serif typeface because it is easier to read. If you are printing the manuscript yourself, you will also want to insure that the typeface is large enough to read. The body of your text should not be any smaller than 10 points and preferably no larger than 12, unless writing for small children or older adults. Finally you must select the type of binding.
Most books use either saddle-stitching or perfect binding.
This option is limited according to the size of the book printed. This is the standard glued-on cover seen in mass paperback books. The pages are separated into groups of 16, the ends roughened, stacked together and then the cover is glued on. This type of binding has the advantage of providing a squared-off spine for printing of the book title and author. Finally you will need to choose the price of your book.