Then press the delete key. You can also drag the icon to the Recycle Bin. Press the left mouse button when your cursor is over the icon. Then hold it down and drag the icon to the Recycle Bin. When the Recycle Bin changes color, let go of the mouse button to drop the icon into the Recycle Bin.
Physical problems make it difficult to work with a mouse.
Try an alternative input device like a large track ball or a touch pad. If at all possible, visit a local computer store where you can try out a variety of devices before you buy. Today, portable computers are just about as powerful as desktop computers. Their smaller size makes them ideal for working in small spaces. But that same small size results in a smaller keyboard, screen, and input device.