Neuroprotective treatment in Huntington's disease. The most promising and widely accepted theory is that the genetic defect eventually leads to a disturbed metabolism in brain cells, making them deficient in energy so that they cannot keep up their full level of functioning and constant cell repair.
Nerve cells seem to become vulnerable to stimulation - especially overstimulation.
Instead, aggressive 'free radicals' will be formed that will attack the membranes of the nerve cells. This will cause a further decrease in energy production in the nerve cells. Early malfunction of the brain can be detected and measured by somatosensory evoked potentials. Their amplitude is diminished after stimulation of the median or tibial nerve. Minimal consumption of alcohol and reduced or better no smoking.