Early diagnosis and timed intervention can improve the outcome for the baby. Jaundice develops two to four weeks later but may not be obvious. Symptoms resolve rapidly after delivery. Women with intrahepatic cholestasis of pregnancy, those with known family members affected or jaundice exacerbated by oral contraceptive pills should be followed closely throughout pregnancy. Some women require supplements of vitamins, particularly vitamin K1 to replace excess loss in their stools.
Maternal outcome is good.
Itching and jaundice resolve rapidly but may recur in other pregnancies and oestrogens. Many treatments have been tried to relieve the itching but should be carefully monitored during pregnancy. Close monitoring of the unborn baby can reduce the risks of premature delivery. Elevated serum levels of maternal bile acids correlate with severity of pruritus and risk of fetal distress. The birth should be planned for two to four weeks earlier than the predicted date, depending on the maturity of the baby.