A physical exam, psychiatric assessment and oral interview are used to screen participants for the study. Once included in the study, participants will begin a ten week active treatment phase. During this time, oral medication will be taken and there will be weekly appointments for behavioral therapy. Phone contact will be maintained at least weekly with participants to adjust medication dosage, assess pain levels, and monitor for any side effects of the medication. Following the active treatment phase, participants will be given a blood test and started on a three month maintenance phase.
Oral medication is continued and participants make monthly visits to the study nurse.
Possible side effects that might require medication adjustment include constipation, nausea, or drowsiness. The study medication will be adjusted for optimal pain relief with minimal side effects. Participants will be able to use over the counter drugs such as Tylenol or Ibuprofen as needed during the study. Participants are free to withdraw from the study at any time. Participants will receive free consultation and remain under close supervision throughout the study period.