Some are cultivated.
Many species possess grapnel or stinging hairs.
Some cultivated forms, some previously known as Caiophora or Loasa , have irritant properties. Caiophora 65 species are native to South America. Cevallia One species is found in the south-western United States and Mexico. Eucnide Ten species are found in the south-western United States and Mexico. Gronovia Two species, native to Mexico, Venezuela and Ecuador possess grapnel or stinging hairs.