The FDA says that approved generic substitutes should render the same therapeutic benefit. Some patients, however, insist they can tell the difference. Generic drugs, if approved by the FDA, are by and large safe and effective. They do help to curb the spiraling cost of healthcare. The therapeutic interchange is more bothersome.
Most physicians are familiar with the drugs which they use frequently.
Health plans insist that exceptions can often be made if the physician calls or writes to them. In practice, however, such application imposes undue hardship on the busy physician. A simple urine test is a simple approach to making the correct diagnosis, but the test underutilized test by most physicians surveyed. Since E. Coli diarrhea in the early stages may present like any other forms of diarrhea, it is important not to use any antimobility or absorbent medications for children with acute diarrhea. Another reason not to use antimobility drugs in children is that the therapeutic dose and toxic dose of these drugs can be very close and may therefore be dangerous.