The incidence is high in Japan where the disease was first described and is now more frequently recognized in the United States.
Risk factors are unknown.
Kawasaki's disease is a poorly understood illness. The disorder affects the mucus membranes, lymph nodes, lining of the blood vessels and the heart. The cardiac involvement and complications are, by far, the most important aspect of the disease. Kawasaki disease often begins with a high and persistent fever that is not very responsive to normal doses of acetaminophen . The fever may persist steadily for up to two weeks.