Neurotrophin mutants and chimeras triNGF , rat NGF with Lys32, Lys34 and Glu35 simultaneously replaced into Ala. Click here to view the entire set available. For references, go to our Structure-Function Relationships Homepage. To request any of the knock-out mice strains listed below, please refer to Patrik Ernfors . Please enclose with your request a brief outline of the proposed research.
Mice lacking brain-derived neurotrophic factor develop with sensory deficits.
Lack of neurotrophin-3 leads to deficiences in the peripheral nervous system and loss of limb proprioceptive afferents. Overexpressors NT4 overexpressor , uses NT4 minigene to amplify NT4 expression in tissues with endogenous expression. For requests, please contact Madis Metsis . Reporter genes under the control of neurotrophin gene promoters To request any of the mice strains listed below, please refer to Madis Metsis . Please enclose with your request a brief outline of the proposed research.