The draft is your first shot at showing the competition who is boss. Although it is not impossible to stink at the draft and still win the bowl, it certainly makes things much easier if you have a solid team from the start. The first step in developing a draft strategy is the same regardless of your league scoring or rules. You must be able to read your league scoring system.
Many leagues try to make all positions equal.
Some leagues have a strong QB or may make TE a lesser impact position. DL is often a less emphasized position. Keep in mind that big play guys tend to be more inconsistent. You may find a few linebackers and defensive ends who have a sack almost every game but interceptions are not predictable. In most leagues that use individual defensive players, the higher scoring players are on the offensive side of the ball.