It appears to take about two weeks for this cycle to normalize where onset of sleep returns to the normal. If you are obese, you will note a decrease in weight over time. However, if you are not obese, you will probably gain a few pounds. This is because your lean body mass will increase and weights more than the body fat that you are loosing. However, clothes will fit better and you will look like you have been loosing weight.
Most people also note a change in facial and body contour.
It may prevent you from getting optimal results. The body knows what it needs and it definitely does NOT need to have the delicate hormonal balance disrupted. So it's better to just leave the individual hormone levels alone. Also, smokers don't get as good a response. Chronically ill people seem to show a negative change initially, similar to a detoxification treatment course, but within two or three weeks, they also show significant positive changes.