Many infections are milder diarrhea or asymptomatic.
Etiologic Agent Vibrio cholerae serogroup O1 or O139 that produces cholera toxin. Incidence 0-5 cases per year in the United States. A major cause of epidemic diarrhea throughout the developing world. Ongoing global pandemic in Asia, Africa and Latin America for the last four decades. Transmission Contaminated drinking water or food.