Some people have long periods of remission, sometimes years when they are free of symptoms. Unfortunately, the disease usually recurs at various times over an individual's lifetime. Although predicting when a flare-up may occur is not possible, early recognition of symptoms results in a better response to treatment. The treatment of ulcerative colitis depends on its severity, location and the presence of complications. It must be individualized.
Most people have mild to moderate disease and are treated with medications containing mesalamine.
These medications include sulfasalazine, Asacol , Pentasa and Dipentum . The medications are usually very well tolerated, and most have no significant side effects. Patients may experience nausea, headache and diarrhea. Diarrhea is particularly a problem with Dipentum . Mesalamine is both useful to achieve and maintain remission.