For an image demonstrating this project, click here . This is a collaborative project with Profs. Peter So and Roger Kamm of the MIT Center for Biomedical Engineering. For updated information on our single cell signaling project, see MIT graduate student Hayden Huang's home page . Small mechanical strains selectively suppress matrix metalloproteinase-1 expression by human vascular smooth muscle cells.
Mechanical strain suppresses inducible nitric oxide synthase in cardiac myocytes.
Matrix metalloproteinase inhibition attenuates early left ventricular enlargement after experimental myocardial infarction in mice. The transcriptional profile of mechanically-induced genes in human vascular smooth muscle cells. Am J Path 2000 in press.