Newton argues eloquently that science is not priesthood preserving a dogma, or a political hierarchy laying down a party line. Scientific knowledge can only be explained as the product of an open self-critical inquiry into external physical reality It is based on observation, bold hypothesis and verification or falsification by experiment. It is dynamic, open, and has given us unparalleled insights and power. In all this he makes it clear that he refers to the truth of physical science. Biology and medicine raise issues not here discussed.
Newton treads a narrow middle path between naive realism and a participatory view of reality.
His explanation of the Bell inequality and non locality is the best I have read. At each stage he shows the rigour of the chain of inference with each closer approximation to reality, while the reality itself becomes less and less certain. In this way he disposes of paranormal phenomena. The paranormal just does not fit in with the total structure of science, and is therefore outside it, and so can be ignored. This is probably fair comment.