Cardiovascular and heart diseases are currently one of the the leading causes of death in all industrialized countries. Cardiovascular diseases are associated with several phenotypes, such as hypertension, thrombosis, and restenosis, which may need to be treated as separate diseases. Genset's comprehensive approach to gene discovery is particularly suited to understanding the genetic causes of these diseases and their complications. Approximately one-third of prostate cancer cases in Caucasians can be attributed to the three genes. Patent applications have been filed on all of these genes.
Prostate cancer is the most common cancer occurring among men.
The American Cancer Society estimates that approximately 185,000 new cases of prostate cancer and more then 39,000 deaths associated with the disease occur in the United States each year. Prostate cancer is a complex common disease and several factors have been implicated, including genetics, diet and certain chemicals. Genset's rapid discovery of genes associated with prostate cancer was a first illustration of the efficiency of our comprehensive approach in gene discovery programs for complex diseases.