This GLP-compliant report can be critical to investigators who are preparing regulatory submissions requiring genotype validation of the animals used in their research whether the animals are Taconic models, the investigator's own transgenic strains, or other research models. It is proof and an assurance that the work has been reviewed and is in compliance with relevant SOPs. If there was the slightest discrepancy anywhere along the line, it is reported and the reponses and the corrective steps are documented. The GLP-complaint report is not a lengthy document. A sophisticated investigator can flip to portions of the report if there is concern about some detail or aspect of the animal or testing involved.
Most investigators just look at the summary, the analysis of the genotype.
The client, the investigator, is involved in the genotyping process from the onset, when he or she is asked to examine and approve the SOP to be used. The client-approved SOPs are entered into the QA's Document Control System, where they are closely tracked. Any subsequent revisions to the SOP also would be entered into the system and the client would be made aware of the revisions. Animal biopsies are tracked and monitored by a sample receipt system. This system is the starting point that enables us to track all DNA samples.