The default layout background contains a grid with the corner points designated. Moving features around on the layout page results in them jumping point to point. However, minor adjustments between grids are not possible. You can type in a layout name for convenience. Go to Layout, Properties, and type in a new name.
Page Orientation Can make a big difference.
If you use one orientation but later decide the other may be better, simply select the other. The map won't change, but elements will be repositioned. Sizes may be changed, also, especially the main map feature. Explore the other Layout, Properties. Usually the main title is in all caps, though it is not required.