The winter weather is not too severe, but storms come in spells. Summer, on the other hand, is often oppressively hot and humid. Swimming holes on Potomac, visible from the rock, may reduce climbing to a secondary objective. Spring and fall offer the best climbing and the most reliable weather. While Bradt, Hubbard, and Moore didn't have to worry about what routes had been climbed in 1939, the current visitor is presented quite a confusing array.
Routes vary in both type and difficulty.
I would recommend the following as some of the most enjoyable and classic climbs on the crag. Eastern rockclimbers have always been noted for the imagination they put into route names. This imagination is particularly evident at Seneca Rock, as a quick review will demonstrate. The easiest route to the summit of anything is the Old Ladies' Route. Only at Seneca has this become the official nomenclature.