Yawning, sedation and penile relaxation occurred 10-30 minutes treatment, coinciding with disappearance of crib biting. Thus, opiate antagonists have clear but short-term therapeutic effect in stereotypic disorder. The outcome of long-term opiate antagonist therapy requires further research. It is suggested that stereotypic behaviour, such as aerophagia, crib biting, hyperkinesis, self mutilation etc activates the brain's pleasure centres and other opiate centres in nervous tissues.
Many drugs act as opiate antagonists.
They include naloxone, naltrexone, nalmefene and diprenorphine. Opiate antagonists displace opiates from their receptor sites, abolishing the pleasurable effect of the opiates or their inductive behaviour. Yin-Yang theory proposes that everything has its opposite. Prolonged electro-stimulation at Earpoint Lung or the mastoid processes is highly successful in alcoholic and narcotic detoxification. A veterinary review.