An excerpt is reproduced here for your convenience. Significant Difference A difference of clinical or public health importance based on substantial scientific data. This definition differs from the commonly used one, which refers to statistical significance. Subpopulations For each minority group, subpopulations are further defined by geographic origins, national origins, or cultural differences. There are different ways of defining and reporting subpopulation data.
People assign themselves to a subpopulation through self-reporting.
Mixed racial or ethnic descent also applies to subpopulations, and such combinations may have biomedical or cultural implications for the scientific question under study. An unbiased assessment that generally yields the correct estimate of the difference in outcomes between two groups of subjects and that should be conducted for both small and large studies. A valid analysis does not need to have a high statistical power for detecting an effect. See also analysis . White A person having origins in any of the original peoples of Europe, the Middle East, or North Africa.