Professor Brown's biostatistics research has included the development of methodologies for the design and the analysis of experiments in all phases of medical research, from the bench to the community. The research is stimu lated by problems brought to the Division of Biostatistics for consultation by faculty and students from all departments in the School of Medicine.
Research methods involve both mathematical work and computer simulation.
A Biomedical Introduction. The crossover experiment for clinical trials. A computer program for designing cancer clinical trials that allows arbitrary specification of survival functions and use of either the log rank or generalized Wilcoxon test. A computer program for designing clinical trials with arbitrary survival curves and group sequential testing. Technical Report No. 143, Division of Biostatistics, Stanford University, June 1991.