Test code links throughout this Guide refer to the corresponding test in the User's Guide.
Rodents are the primarily reservoir.
Clinically, infection usually presents as an acute influenza-like illness. Symptoms develop 5-10 days after exposure. Some patients may experience sore throat. Symptoms may improve after five days to three weeks, but some suffer relapse with meningeal symptoms. The CF test is often used to screen aseptic meningitis specimens against a battery of antigens and a CF antigen is often appropriately included in this battery.