The primary source of ethylene glycol is from antifreeze used in car engines and sometimes in toliets to prevent freezing. Species vary in susceptibility. Despite species differences, most animals find the chemical to be palatable and will consume large quantities, if available.
Metabolism takes place primarily in liver and to a lesser degree, in the kidneys.
This is the rate limiting step in metabolism. Metabolism continues to glycolate, then to glyoxylate, then to glycine and oxalate. The glycine is later converted to hippuric acid. Oxalate binds to calcium. EG itself is not very toxic, most is excreted by the kidneys unchanged.