Such areas will get infected quickly and such infections will lead to many types of disease. In the wild, many animals which receive quills in their mouth are unable to eat and will eventually starve . Dogs which try to bite will find out porcupines aren't good eating, but only a few seem to learn from their experience. Most which get a mouthful don't seem to learn. It's not unusual to see them back at the vet's some time in the future.
Porcupines have one litter in the spring.
They almost always have one young and twins are very rare. Their gestation is long for a rodent, about seven months. Young porcupines can walk almost immediately and will climb trees within two days . At ten days, most are on their own. By their second year, they are able to reproduce.