It is theorized that the allergen sticks to clothing of individuals who live with a pet, and transfer the allergen to furnishings at their place of work or school. Thus, children without at pet at home may be sensitized and symptomatic from this passive transfer of allergen. The source of the pet's allergen varies among species. The major cat allergen, Fel d1, is found primarily in the cat's epidermis, but is also present in saliva, and to some extent, in the urine. Can F 1, is largely secreted through the skin to the fur.
Rodent urine is usually the main source of allergen.
Both cat and dog allergens can remain airborne for long periods of time because of their aerodynamic and small particle size. Reducing indoor cat, dog and other pet allergen levels is challenging. Ideally the pet should be kept outdoors, but certainly out of the patient's bedroom. If possible, the vents to the bedroom should be closed as well. At least weekly laundry of the patient's bedding and clothing will remove this water-soluble allergen.