Measles - Rubeola. Serious illness characterized by high fever and rash. Virus enters via nose, mouth or conjunctiva. Koplik spots appear on the buccal mucosa 2-3 days before the rash and fever. Rash is caused by T cells killing virus in capillaries - but if this doesn't happen, virus becomes disseminated and causes encephalitis, or lung or kidney damage.
Rubeola can be fatal.
Fig 21.13 Recent epidemics of measles in college students may be because immunity isn't lifelong, or immunization took place too early. Evidently they once were protected by maternal Ab, but mothers who got vaccine rather than the illness don't have Ab that lasts as long. But the vaccine itself can't be given until around 12 months or it isn't effective. Problem of complacency - parents not getting children immunized 3. Fig 21.10 a.