The number of people needing transplants is increasing, each year.
Rejection is the body's natural reaction to transplanted organs and tissues.
This threatens each patient with the loss of the new organ or even loss of life. There are several underserved populations, receiving fewer transplants than expected from their numbers on waiting lists. Moving scientific discoveries from the laboratory bench to the bedside requires special efforts and careful planning to translate science into improved medical practice. Prevent graft rejection by learning the processes used by the body not only to recognize transplants as foreign but also to reject them. Identify and develop ways to overcome the biological barriers to transplantation that put certain groups of patients at a disadvantage.