It is a physico-chemical parameter that has a correlation with absorption of small molecules into physiological membranes.
P refers to the neutral form of the compound.
PrologP 5.1 is the latest version of CompuDrug's log P prediction program. A further developed version of Rekker's fragmental method, the atomic approaches of Broto et al. and Ghose et al. are applied. The predicted results of these methods are combined in order to minimize the error of the estimation. To download the PrologP manual click here Support for QSAR One advantage of the PrologP program is that it allows you to save your results into a spreadsheet format for further data processing such as QSAR calculations. For defining the organic solvent conc.