Ten patients were boosted with implants or electrons and 6 others underwent local excision. The median follow-up was 34 months. Responses were determined clinically 1 month after completion of the radiation and chemotherapy. All five treatment failures occurred within 6 months of treatment. Concurrent radiation therapy and chemotherapy with local excision performed as needed, appears to be a reasonable alternative to radical vulvectomy in patients with primary squamous cell carcinoma of the vulva.
Radical surgery remains a viable option for patients in whom primary therapy has failed.
Epidermoid carcinoma is the most frequent neoplasia of the vulva. At other times a dangerous shyness causes considerable delays by postponing the visit to the specialist. Many patients refuse to go to see a physician. The existence of urinary signs and symptoms in a patient with vulvar neoplasia are indicative of urethral invasion and the advanced stage of the condition. A case is presented here of an advanced vulva carcinoma in an 82 year-old woman who come with urinary retention by urethral infiltration and perineal destruction.