The laboratory, under the guidance of Thomas J. Kuehl, Ph.D., is a resource and research facility focused primarily on the application of P olymerase C hain R eation technology to address difficult DNA detection problems. The focus of this laboratory is on the development of assays to detect individual copies of one or more gene sequences.
Methods typically start with nonspecific amplification of DNA from one or more cells.
Finally, the specific products are assayed for size and presence of restriction endonuclease sites. In this way we apply existing technologies and Internet resources recombinant with DNAsequence data to interesting research applications. This facility is designed with the capability of going from idea on a chalk board to product in the form of bands on gels. All rights reserved.