Located in the Cambridge Science Park, Camitro UK enjoys close contact with the University of Cambridge and many high-tech companies. In addition, this site provides a base of support for Camitro's European customers. Absorption generally refers to the amount of drug compound that enters the portal vein following oral administration. The transfer of compound from the site of administration to the total systemic circulation and then to the various tissues of the body is called distribution .
Metabolism is the enzymatic conversion of one chemical species to another.
Elimination is the removal of compounds from the body via a number of pathways, primarily through urine and bile. Tox Profiles ADME profiles refer to the drug concentration at various sites in the body over time. The cumulative effects of rate of absorption, distribution, metabolism, and elimination determine drug concentration at the intended site. Tox profiles refer to the toxic side effect of the drug on various tissues. Combinatorial Chemistry Combinatorial chemistry is the process by which large libraries of drug-like molecules, based upon a shared chemistry, can be efficiently assembled in modular fashion using sets of individual building blocks or monomers.