Bruce Hudson . This quenches the fluorescence of the tryptophan and is the basis for a sensitive assay for binding to the protein. Watson Lees . Small molecules might catalyze the disulfide bond rearrangement of proteins, a topic of work in our lab. Stewart Loh .
Protein folding is a multistep process.
We focus on characterizing folding intermediates. Our work includes NMR spectroscopy as well as methods in molecular biology, biochemistry, and biophysics. Jim Kallmerten . Staggered labeling like this should make it easier to interpret NMR relaxation measurements to extract information on internal and overall motion. Jim Dabrowiak and Jerry Goodisman .