The tracer that had been injected into non-acupoints diffused in a centrifugal pattern. Another researcher by the name of Mussat investigated the propagation of electical current from a single acupoint to another distal acupoint along the same channel. His work supported this theory, however, his work has not been supported by any other research. PSAC sensation also supports the channel theory. A large body of research addresses the mechanisms of acupuncture s central nervous system effects.
Opiate antagonists are able to block acupuncture analgesia.
Lab animals deficient in opiate receptors or endorphic production do not respond to acupuncture analgesia. Lack of central endorphins truncates acupuncture analgesia. Effects may be enhanced by inhibiting enzyme degradation of the endorphin molecules. Acupuncture analgesia can be evoked in the recipient of cerebrospinal fluid from an animal who received acupuncture. This effect can be blocked in the recipient animal by opiate antagonists.