He completed a post-doctoral program in Neurochemistry in the School of Medicine, Indiana University, Indianapolis. He was a Lecturer in the Department of Neurochemistry at the Institute of Neurology, University of London, and an Associate Professor in the Departments of Neurology and Neurosciences, Albert Einstein College of Medicine, New York. He has special expertise in Biochemical Neurotoxicology, axonal transport, energy perturbation and myelination in the developing brain. Research Interests Dr. Sabri's research investigates the biochemical mechanisms underlying human neurological diseases of unknown etiology. He studies neurochemical mechanisms of mammalian neural dysfunction by utilizing environmental toxins known to induce primary axonal and selective neuronal degeneration in humans and animals.
Old animals appear more vulnerable than young animals.
Dr. Sabri is examining this age-dependent differential susceptibility in relation to energy generation in the brain. Dr. Sabri is also interested in excitotoxicity, free radicals, oxidative stress, glutathione system in relation to toxin induced neuronal injury in rodent brain. Since these genes are expressed early following toxin treatment, its expression can be used as a biomarker of neurotoxic exposure. Brain Res . Acrylamide alters immediate-early gene expression in rat brain.