Similarly, aquatic reptiles and mammals are not strongly effected by Rotenone because they have no gills. Rotenone is used in the agricultural arena as an insecticide. It is regularly applied foliarly to crops of potatoes, tomatoes, pears, and apples before the harvest. Application is usually accomplished by dusting or spraying, with the intent of protecting crops against crawling and flying insect pests. The effects of Rotenone can be reversed by Methyl Blue, but it is not done very often.
Rotenone is fairly unstable, with a half life of under a week.
Miyano, J., Journal of the American Chemical Society.