These are multidisciplinary clinics consisting of specialists from areas involved in the patient's management. Pediatric oncologists, radiation oncologists, neurosurgeons, neurologists, developmental neuropsychologists, nurse practitioners, oncology nurses, dieticians, child life specialists and social workers are present at each comprehensive brain tumor clinic. All patients are managed by a comprehensive care team consisting of a nurse practitioner, pediatric oncologists, oncology social worker, nurse specialist, dietician, pharmacist, and oncology nurses. The program has been structured as a pediatric oncology service line providing comprehensive care across the continuum. Acute Lymphoblastic Leukemia Strategy Group and Steering Committee, Acute Myeloid Leukemia Strategy Group and Steering Committee, CCG Executive Committee, CCG Voting Body, Biology and Translational Research Program, Brain Tumor Committee, Discipline Committee, Publication Committee.
Oncologists are principal investigators on numerous studies including the relapsed ALL committee.
The Physicians and Support Staff of the Pediatric Oncology Program have an active basic, clinical and translational research program. Five of the division members have extramurally funded basic laboratory research programs with the majority of their time spent in laboratory research activities. Areas of research include N-myc promoter function and regulation of gene expression, mechanism of DNA replication, mutator phenotype, gene mutation and repair, DNA repair, chromosomal translocations in childhood cancers, hematopoietic stem cells and regulation of hematopoiesis, and use of transgenic mice for study of gene expression and induction of childhood cancers. Translational research projects are focused in high risk, relapsed and resistant acute leukemias, brain tumors and high risk and metastatic sarcomas. These include studies of gene expression, apoptosis and regulation of cellular differentiation.