If a person is not sensitized, no symptoms may be evident, only a purpuric macule at the bite site. Old furniture makes an excellent home for bedbugs. They also like to hide in the seams and folds of mattresses and in bed frames and springs. Most reactions to bedbugs show a superficial and deep perivascular infiltrate containing mixed cells with eosinophils rather than neutrophils being prominent. Eosinophils may be prominent among collagen bundles, or may be absent.
Medical care depends on the clinical picture.
Bedbug bites usually do not require any treatment. Apply local antiseptic lotion or antibiotic cream or ointment if secondary infection occurs. Creams with corticosteroids and oral antihistamines may be advised in the presence of allergic reaction. The goal of pharmacotherapy is to reduce morbidity and prevent complications. They modify the body's immune response to diverse stimuli.