With 20 technologies in various stages of development and 6 of those in advanced stages, the center has already become a virtual pharmaceutical company, he said. In closing, Dr. Rubin reminded the guests that translating academic research into economic benefit takes resources, and he hoped that the Center proved worthy of continued support and investment. The vision is up and running. This amounts to the administration of two to four million doses a year, worldwide. A team of BNL and USB scientists has recently made significant advances in the quantitative applications of MRI CRs.
Quantitative studies treat the CR as a non-radioactive tracer.
A basic quantity pertaining to a tracer is its concentration. This requires a calibration relationship between R and the CR concentration. When studied as aqueous CR solutions in test tubes, one finds that R is a linear function of CR concentration. The assumption of the linear calibration relationship requires that this exchange be effectively infinitely fast. The dependence of R on CR concentration in vivo is distinctly non-linear.