Use caution crossing US ALT 27, a 4 lane, divided highway and the nearby railroad tracks. The final 6 miles into Manatee Springs State Park are also becoming more congested. Stay alert to traffic. The route is over mostly rural roads with few stores available. High Springs and Chiefland are the biggest towns.
Numerous restaurants including vegetarian, grocery and hardware stores are in High Springs.
Convenience store locations are at the intersection with SR 47 and between Chiefland and the state park. The route does go directly behind the Chiefland Regional Shopping Center, just before heading toward Manatee Springs. Directions from O'Leno State Park to Manatee Springs State Park 0.0 Park Entrance Station. 0.3 Turn left onto frontage road. 0.5 Turn left onto US 441.