This is a serious condition caused by infection of trapped red blood cells in the lungs. This results in fast or difficult breathing, chest pain, and coughing. Bone Necrosis - Degradation of bone tissue which can lead to hip replacements and other complications. The risk of infection is increased because the spleen does not function properly. The spleen is the organ that filters blood.
Rapid enlargement can result due to entrapment of sickled cells in the spleen.
This condition can be fatal. Stroke - Occurs when sickled cells create a blockage within the brain. Signs include seizure, weakness in the arms and legs, speech problems, and loss of consciousness. There is no universal cure for sickle cell disease. Research in gene therapy, the ultimate universal cure, is currently underway which hope to offer a permanant and effective cure for this disorder.