You can't give up if the chemistry doesn't feel right at the first meeting. We suggest a minimum of one meeting per month. It's important to touch base regularly - by email, by phone. Some people meet at the gym for a workout. I've taken my protege to a baseball game.
Nothing kills trust in a mentoring relationship faster than a breach of confidence.
You need to pick up on cultural and gender differences. If you're paired with someone who differs from you in either race or gender, or both, be sensitive to these differences. You're in this to learn, whether you're a protege or a mentor. Do a little homework.