The efficacy of these immunological therapies will be determined by monitoring the dynamics of viral rebound upon cessation of antiviral therapy. The efficacy of these immunological therapies will be determined by monitoring the dynamics of viral rebound upon cessation of antiviral therapy. Phase Phase II A phase two trial follows phase one. It consists of a larger, randomized sample of patients. The purpose of a phase two trial is to see if the drug is effective at doing what the manufacturer claims it should do.
Researchers also watch closely for unexpected adverse reactions.
4 arms of 23 patients each. Topical corticosteroids at a site separate from IL-2 and vaccine injection sites. Maintenance therapy for opportunistic infections that develop on study treatment according to standard medical care, except for foscarnet during IL-2 administration, and rifabutin and rifampin at any time. Antibiotics for bacterial infections as clinically indicated. Medications for symptomatic treatment such as antipyretics and analgesics.