Identification of specific epitopes would be helpful. Since sialylated polysaccharides are suspect, a probe to detect the presence of sialyl transferase may be helpful in identifying GBS-associated strains. The mechanism of immune mediated nerve damage is poorly understood. Why gangliosides on nerves are particularly targeted or sensitive when compared to the same molecules found on other tissues is not known. Studies should be done to try to understand the variations noted in seasonality, or lack thereof, of GBS, and of the basis for the differences noted in the serotypes of C. jejuni that have been associated with the onset of GBS in different studies and in different regions of the world.
More research is needed with the aim of developing improved therapies.
The ability to send such information to an Internet address, for example, that would be widely accessible was discussed. Posting of interesting new observations, information, or questions would facilitate research efforts by all involved. Information on DNA sequences, availability of new strains or reagents, new techniques, reservoirs of infection, structures of LPS or proteins, new typing methods, antibiotic resistance patterns, frequency of isolation of particular serotypes associated with GBS, epidemiology, etc. could be included in such an exchange.