The annotation consists of promoter regions predicted by PromoterInspector . GPR predicts approximately every second pol II promoter. GPR contains close to 10 times more promoters than published in the EMBL database. The GPR contains both CpG island and non CpG island promoters.
Promoters are the final processors of transcription signals.
They are responsible for Tissue-specificity Signal transduction Locating promoters in the genome is a prerequisite for all further analyses. GPR application GPR is the most important genomic annotation next to coding regions. GPR can enhance in silico gene finding . GPR allows systematic detection of regulatory SNPs . GPR allows to assess regulatory networks on molecular level.