Amendment in the nature of a substitute as an original bill for purposes of amendment. This is done to permit second degree amendments to be offered. Otherwise, the substitute would be considered a first degree amendment, and would only be subject to further non-amendable amendments. Open rules customarily grant the Chair discretion to give priority in recognition to Members who have pre-printed their amendments in the Congressional Record. But absent this provision, the Chair would follow the custom of giving preferential recognition to Members, based on seniority, who serve on the reporting committee, alternating between the parties.
Most votes win.
A special rule may permit Members to vote on two or more amendments in the nature of a substitute to the same bill, or parts of the same bill. If more than one substitute attracts a majority of votes, the Committee of the Whole reports only the one that receives the largest number of votes.