It is not Isaiah's prayer that God remain distant and aloof and uninvolved. How very different this is from the billboard's message. Isaiah's plea to God is my plea to God too. I look around this first Sunday of Advent, and in spite of some 2800 years between us and Isaiah, I don't think it is so different. People kill one another for simply stupid reasons.
People feel isolated, alone, empty, and full of themselves.
We live lives as if there is no God. People who love one another deeply say and do terrible things to one another and create heartache. We are in need of God's inbreaking to reshape and mold us. But instead, we are proud people. We would rather accept our familiar pain than to risk what God has in store for us.