Specific hepatitis B immunoglobulin and hepatitis B vaccine are given together in post-exposure prophylaxis. Specific tetanus immunoglobulin and tetanus toxoid are given together in post-exposure prophylaxis. Do not give live vaccines for 6 months after stopping antineoplastic drugs. Oral typhoid vaccine is inactivated by certain antibiotics. BCG is inactivated by antituberculous drugs.
Rabies vaccine is affected by mefloquine and chloroquine.
Try to complete the rabies immunisation schedule 1 or 2 months before malaria prophylaxis is needed. Varicella vaccine is inactivated by acyclovir. Other drugs Influenza vaccine may potentiate the effects of phenytoin, theophylline derivatives and warfarin. Any suggestion of either of these demands admission to hospital and parenteral treatment - seek expert advice early. Shingles in the pregnant mother does not confer any risk on the fetus.