Please refer to SWOG-9205 for details. All patients must have prestudy PSA within 28 days prior to registration. All patients must have had a CT scan of the abdomen and pelvis within 28 days prior to registration. Patients must also have had a bone scan within 42 days prior to registration. Patients must have received prior hormonal therapy.
Patients treated with orchiectomy are eligible.
At least 28 days must have elapsed since the completion of radiation therapy and the patient must have recovered from side effects. Soft tissue disease which has been radiated in the prior two months is not assessable as measurable disease. Patients may have received prior surgery. However, at least 21 days must have elapsed since completion of surgery and patient must have recovered from all side effects. Prior therapy must not have included estramustine, taxanes, or anthracyclines, or mitoxantrone.