Dosages should be individualized for each patient. Treatment is contraindicated during hypoglycemic episodes and in patients with a prior hypersensitivity to insulin lispro or any of its ingredients. Glucose monitoring is recommended for all diabetic patients. No well-controlled trials have been performed in pregnant women. Reproduction studies in rats and rabbits have not shown any evidence of harm to the fetus or fertility.
Regular insulin is the drug of choice for diabetic pregnant patients and during breast- feeding.
Careful blood glucose monitoring is recommended. Careful blood glucose monitoring is recommended. Insulin needs may decrease with medications that have hypoglycemic effects. Beta-adrenergic blockers may mask the symptoms of hypoglycemia in some patients. When compared to other human insulin mixtures, no difference in adverse effect frequency was observed.