If not treated, muscle bleeding can lead to significant blood loss from the circulation into a muscle. This bleeding does not typically require treatment with factor replacement unless it occurs in a small space such as around the eye or in a finger or toe. Blood in the urine may occur spontaneously in persons with hemophilia. If these episodes are painless, do not cause significant blood loss, and resolve on their own, they are usually not cause for concern. If however, these episodes continue, lead to significant blood loss, are associated with pain, or recur frequently, they should be evaluated.
Nose bleeding in persons with hemophilia is unlikely to occur more frequently than for others.
If it occurs frequently, results in significant blood loss, or interferes with activities, it should be evaluated and treated. Lacerations Cuts or lacerations requiring sutures should be treated with factor replacement therapy in persons with hemophilia. During suture removal, the person with hemophilia should also receive factor replacement therapy. Even if suspected bleeding or trauma occurs to the head, immediate treatment should be sought. Some of these sites of bleeding can occur without know trauma, therefore bleeding into these areas requires treatment.