Unfortunately, it will take a lot more study to see if these subgroups of reflux really exist. The genetic study is, however, a good first step in that direction. Currently, the diagnostic process relies heavily on medical suspicion and invasive tests such as acidity probes, barium swallow, scintigraphy and endoscopy. These tests, while not painful, are often quite traumatic for children. In order to accomplish this, more families that have a strong history of reflux need to be identified and studied.
Researchers hope to have a commercially available test for genetic reflux within a few years.
At this point, researchers can't tell patients if they carry the genetic mutation associated with reflux. It is also remains to be seen whether the inherited form of reflux has a better or worse prognosis than non-inherited forms. But reflux patients can help researchers now by providing very valuable information about their symptoms and history of disease. If your family has a history of acid reflux, you are encouraged to learn more about the study being conducted at Allegheny General Hospital , Center for Genomic Sciences. You do not need to travel to participate.