Postthrombotic syndrome is an important late complication after deep vein thrombosis in pregnancy.
Thrombolytic agents are more efficient in preventing this condition but are rarely used in pregnant women. After application of a heparin bolus, systemic streptokinase lysis was performed. Low-dose heparin therapy was continued for the remainder of the, otherwise unremarkable, pregnancy. Spontaneous delivery of a healthy girl was without complications and thromboprophylaxis with low-molecular heparin was continued. Thrombolysis in pregnancy is possible and may help to prevent severe long-term sequelae of thrombosis in young women.