In some individuals, the body will not allow such self-reactive antibodies to exist, because they are harmful to the body, and destroys them. This is known as an anergy reaction. A full spectrum of reactions. In practice, mycobacteriosis patients seldom exhibit the extreme contained or aggressive forms described above, but exhibit a form that is a hybrid of the two. Immunology research, where researchers seek to measure the bodies immune response to various bacterial antigens, are highly specific.
Most research looks for an humoral response or for a CMI response.
Statistical analysis of results of such searches, without first dividing the patients into two groups that represent the different forms, will yield random results.