You have to have a lot of cell death in order to see a complete loss of liver function. The more necrosis you have, the more ALT and AST you see in the blood. Since collagen contracts, we might expect a cirrhotic liver to be smaller than usual. Increasing cardiac sphincter tone will worsen heartburn because swallowing will be slower. Increasing the rate of stomach emptying increases heartburn risk.
Prostaglandins inhibit mucus formation in the stomach.
Stomach acid is produced by an acid pump in the chief cells.