Coal and diamonds are both carbon solids, yet their entropy is very different. I don't know the numbers, but this does not seem right. I think of molecules larger and more complex than CH2. A simple sugar has 5 or 6 carbons. Amino acids vary having 2 - 9 or so carbons each.
Nucleotides have several carbons.
Ultimately they become our fossil fuels. We learned how to calculate this in freshman chemistry. I could try to revisit this. My gut tells me these reactions are both entropically and enthalpically driven. Maybe you know better.