However, MRS measures the metabolites in the body, whereas, MRI gives anatomical information. We are using MRS in cardiac studies, in evaluating brain function, and in monitoring therapy. The MS student would have the opportunity to learn this new technique, and to work in an interdisciplinary environment. I have a Ph. D. student and a post-doc working with me. Metabolic Determinants of Endogenous Nitric Oxide Expression .
Nitric oxide is produced in vivo enzymatically from the guanidino group on L-arginine.
Overproduction of nitric oxide can occur following stimulation from septicemia, hemorrhagic shock, and other causes. Our laboratory is involved in evaluating how endogenous expression of nitric oxide is regulated. Nitric Oxide Inhalation Therapy. Nitric oxide inhalation therapy is rapidly evolving into a standard means of lowering pulmonary vascular resistance and improving ventilation perfusion abnormalities in critically ill patients. The clinical research arm of our laboratory recently has been involved in studies of the physiologic effects of nitric oxide delivery to preterm infants.