Due to potassium depletion, the action of cardiac glycosides may be strengthened. May antagonize antidiarrheal drugs. Thiazide diuretics, cortico-adrenal steroids and licorice root may further deplete potassium. Diarrhea, intestinal sluggishness, nausea, vomiting. Cramp-like discomfort of GI tract.
Potassium deficiency can lead to cardiac dysfunction and muscular weakness.
Habitual use may induce chronic diarrhea with weakness from excessive loss of potassium. Melanin will pigmentize the mucous membranes of the colon. Limit use to 8 days for aged bark, 2-3 days for the tea. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs, and Cosmetics, 2d ed. Castleman M. The Healing Herbs.