Unfortunately, many of these patients developed dry eye later on in life. It was soon discovered that the nictitans gland was an important organ involved in proper tear production which needed to be preserved. KCS can also be caused by a reaction to medications. Sulfonamide antibiotics have been implicated as contributors to this condition. Previous eye surgeries or genetic predisposition may influence the manifestation of the syndrome.
Most cases are controllable with regular treatment.
Except for some instances of drug or allergic reactions, KCS generally requires lifelong management.