Lenders like to see low debt and cash reserves in the bank. You can order your own credit report, which most credit card companies offer you to view for free a couple of times a year. Take them up on it. Be an informed buyer and check with your real estate agent about each of the potential neighborhoods that may be of interest to you. All of these items are very important.
Many properties have inspections right up front.
The seller will have them readily available in the house for a buyer to review. This is very helpful, so you know the condition of the property up front, but never be afraid to ask questions. There is a lot of information to take in, so don't be shy. Your realtor does not know what you do and don't know. Constant communication is of paramount importance.