The process has been well-documented in liver cancer. Free radical damage occurs first, then cirrhosis , then cancer. SAMe, or methyl factors that increase SAMe, can reverse the process. SAMe's ability to reverse cancer in animals has been shown. The above study was done on animals, and pertains only to liver cancer.
Most cancers are methionine-dependent.
Patients with cancer should never take supplemental methionine. When SAMe is used for methylation, a chemical reaction occurs where a methyl group is lost, and a by-product is created. This by-product is homocysteine. Homocysteine has gotten a lot of press recently as a culprit in heart attack and stroke. But homocysteine is not a bad thing in and of itself.