Medroxyprogesterone is relatively contraindicated in patients who have progestin intolerance, major depression, thrombophlebitis, thromboembolic disease, or a history of cerebrovascular accident including cerebral hemorrhage. Medroxyprogesterone should not be used if there is a history of ectopic pregnancy, during the first four months of pregnancy, or in diagnostic tests for pregnancy. It is secreted in milk, so alternative methods to breast-feeding should be employed. These drugs should not be used together. Other adverse reactions that can occur during therapy with medroxyprogesterone are hirsutism, breast tenderness, impotence, anxiety, and diarrhea.
Medroxyprogesterone is a man-made steroid that acts like the natural hormone progesterone.
Natural progesterone is essential to normal reproductive functioning of the womb and reproductive system. Generic medroxyprogesterone tablets are not yet available. Take medroxyprogesterone tablets by mouth. Follow the directions on the prescription label. Swallow the tablets with a drink of water.