Through the P2 Framework, OPPT is presenting these screening models to industry and other stakeholders in the hopes that use of these models early in the research and development process will result in safer chemicals entering commerce. The P2 Framework models should be used for priority setting and to produce additional information so that choices can be made o the chemicals being evaluated. Other chemical screening methodologies have been developed and are in use by chemical companies and other stakeholders. The Agency recognizes that other models are available and that these models can also be of value in chemical screening efforts. Screening models predict data with an inherent degree of uncertainty, and should never be used to replace measured data from well designed studies.
Measured data are always preferred over predicted data.
If measured data is not available, measured data on close analogs can be used. If no analog data are available, screening level models, such as the P2 Framework, may be used for priority setting and to predict values that can be used to indicate which chemicals may need further testing or evaluation. A simple to read and use P2 Framework Manual was developed which describes the models integrated into the P2 Framework and explains what each model does and what is needed to use it. P2 Workshops and Presentations have been conducted to present the P2 models to industry and other stakeholders. Kodak's success using the P2 Models provided the impetus for OPPT to conduct nation-wide workshops to introduce the models to other industry sectors.