Bases are complementary and can bind with their counterpart in a process known as base-pairing. These compounds suppress retroviral replication by interfering with the reverse transcriptase enzyme. The defective synthetic nucleosides cause premature termination of the viral DNA chain. Nucleoside analogs are prodrugs that are converted into active agents by phosphorylation. The defective synthetic nucleotide interferes with viral replication by causing premature termination of the viral DNA chain.
Nutrients act as cofactors in many vital physiological processes.