Symptomatic patients should be referred to the appropriate specialist depending on the organ system involved. In cases with familial occurrence, patients should be referred for genetic counseling. New GI lesions may continue to occur, so patients need periodic GI and hematologic surveillance studies. Rarely, acute GI hemorrhage or CNS involvement may result in death. The prognosis depends on the extent of visceral organ involvement.
Most patients have a normal life span.
Spinal cord compression in blue rubber bleb nevus syndrome. MR imaging of blue rubber bleb nevus syndrome. Orthopaedic dysfunction in the blue rubber-bleb nevus syndrome. Tender bluish papules on the trunk and extremities. Blue rubber-bleb nevus syndrome.