These factors also appear to be developmentally regulated, since the age at which a neuro-epithelial cell differentiates determines the range of neuronal phenotypes that it can express. This work involves studies of both developing and regenerating retina, including both in vivo and in vitro experimental approaches. Basic fibroblast growth factor induces retinal pigment epithelium to generate neural retina in vitro. Cellular interactions determine neuronal phenotypes in rodent retinal cultures. Perspectives in Dev.
Retinoic acid promotes photoreceptor differentiation in rat retinal cell cultures.