The main role of UNEP and the partner agencies is to promote and facilitate implementation of the Global Programme of Action at the national, regional and international level, keeping in mind paragraphs 74-79 of the Programme of Action. The need to harmonize national actions in case of enclosed or semi-enclosed seas is evident, although the arguments in favour of global harmonization are equally strong. Cooperation on global and regional levels will highlight the importance of identifying those regional and global issues which, because of their transboundary and primarily international impact, rarely attain high place on national agendas. An example for such a regional issue is the issue of eutrophication.
POPs are a more global issue with a more complex but equally valid economic arguments.