However, many people disagree with the common practice of performing the surgery at a very early age, and prefer to wait until the ferret is at least six months old. There's debate about whether descenting ferrets is necessary or useful, and some belief that it's harmful. It's bad for a ferret's health to descent it before 6 or 7 weeks of age, and it may be somewhat harmful when done at any age. Note that, like a skunk, a ferret will use its scent if it's greatly distressed or feeling amorous, but ferrets can't spray their scent as effectively as a skunk, it doesn't smell as bad, and it dissipates in just a few seconds. How often a ferret sprays and how bad it smells depend on the individual ferret, and different people have different tolerances for the scent, so if given the option you may want to wait and see if you think descenting is necessary in your particular case.
Most pet stores sell neutered and descented kits.
Many breeders sell kits which have been neutered but not descented. Ferrets have nails like dogs, not cats. Claws are used for walking, as well as, balancing themselves. They should NOT be declawed. Annual distemper and rabies vaccinations are state required.