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Nitrous oxide is a most pleasant trip, giving relaxation and simple intoxication.
It is not by itself the best pain-killer, which is why dentists use novocaine in conjunction with nitrous oxide. But intoxication makes any dental procedure less tedious. Additionally, at higher doses, time passes quickly, and one's memory of events taking place is spotty. There have been rare cases of dentists having sex with patients passed out on nitrous oxide, as suggested on a Seinfeld episode. Once the gas stops, sobriety returns quickly, but relaxation may remain throughout the day.