Deep skin incisional biopsies are required to adequately sample the subcutaneous tissue. Findings are localized to the subcutaneous tissue. The classic features of CP on histopathology predominantly are a lobular panniculitis with scattered lymphohistiocytic and eosinophilic infiltrates. The deposition of mucin is a special finding. In most instances, CP is a self-limiting disorder and requires only symptomatic relief.
Many patients recover if slow rewarming is achieved.
CP is a self-limiting disorder. The prognosis is excellent because most cases resolve without adverse affects. Educate patients about avoiding exposure to cold. Exclude other significant underlying diseases. Equestrian cold panniculitis in women.