Hot flashes were somewhat increased in the SERM group and decreased in the HRT group relative to placebo. In another study, the SERM did not significantly stimulate the endometrium, whereas estrogen alone did. Osteoporosis is an important cause of morbidity in women. Screening consists of assessment of clinical risk and measurement of bone mineral density. Several treatment options are now available for post menopausal women.
Many issues involving prevention and management of osteoporosis remain unresolved.
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