Lack of lubrication tends to be a more common problem with aging, particularly during and after menopause. Estrogen replacement therapy often reduces the problem and helps to maintain the viability of the vagina as well. It is possible to use artificial lubricants such as various commercially sold jellies and creams to assist in achieving adequate lubrication. Water-based lubricants are more easily absorbed by and are less irritating to the delicate tissues in and around the genitals. Individuals who engage in anal intercourse, in which the penis is inserted into the partner's anus, should use artificial lubrication because of the lack of lubricating glands in the anus.
Many males also use artificial lubricants to facilitate masturbation.