2D electron microscope images Standard technique for noise reduction in biological electron microscopy is averaging over identically reproducible structures.
Problem is the detection of structures in the images in an automated fashion.
I Alpha-subunit of Thermoplasma acidophylum , negative staining, fixation on carbon foil, diameter ca. Example III 26S proteasome of Xenopus laevis , negative staining, fixation on carbon foil, length ca. Example IV 20S proteasome of Xenopus laevis , negative staining, fixation on carbon foil, length ca.