All five treatment failures occurred within 6 months of treatment. Concurrent radiation therapy and chemotherapy with local excision performed as needed, appears to be a reasonable alternative to radical vulvectomy in patients with primary squamous cell carcinoma of the vulva. Radical surgery remains a viable option for patients in whom primary therapy has failed. Epidermoid carcinoma is the most frequent neoplasia of the vulva. At other times a dangerous shyness causes considerable delays by postponing the visit to the specialist.
Many patients refuse to go to see a physician.
The existence of urinary signs and symptoms in a patient with vulvar neoplasia are indicative of urethral invasion and the advanced stage of the condition. A case is presented here of an advanced vulva carcinoma in an 82 year-old woman who come with urinary retention by urethral infiltration and perineal destruction. We review the most relevant aspects of vulvar carcinomas associated with obstructive uropathy. All PCR products were hybridized to type-specific radiolabeled probes. The association between the presence of HPV DNA and histologic, epidemiologic, and clinical characteristics was analyzed.