It was distinguished from Wegener granulomatosis in the 1980s based on the differences in lung abnormalities. The average age of onset is 50 years, and it is very rare in children. The disease affects both sexes equally. Clinical features include constitutional symptoms such as fever, anorexia, fatigue, and weight loss. Another characteristic feature is rapidly progressive glomerulonephritis, which often affects the kidneys in the early stages of the condition.
Peripheral neuropathy occurs in about a third of patients.
Ocular lesions are seen in MPA and may include conjunctivitis, scleritis, and uveitis. The prognosis and outcome of MPA depends on the extent and severity of organ involvement. 9 Early diagnosis and prompt institution of steroids and cyclophosphamide is essential. Azathioprine can be used to maintain remission in patients who develop hemorrhagic cystitis. Our report describes MPA in an adolescent patient.