It also prevents the body from relying solely on the process of glycolysis, which produces a net of two ATP molecules, but has the byproduct of lactic acid. These two studies together seem to imply that creatine is a largely anaerobic process. However, research remains to be done on this subject. Although creatine is generally used as a supplement for short, intense activity, athletes to increase muscle mass often use it. It is also suggests that this increase in muscle mass may be attributable to increased protein or increased water in muscle.
Research reveals that individual response to creatine varies.
For example, those with restricted meat intake or who are vegetarians will see the most dramatic results. It is also noted that females posses higher levels of creatine, and older individuals possess less. These results suggest that response to creatine supplementation is relative and depends on how much creatine is in one system prior to ingestion of creatine. Stout et al. Subjects had not ingested creatine or any other supplements for a minimum of 12 weeks before the study, and were asked to abstain from the use of such products for the duration of the study reveal that creatine loading delayed the onset of neuromuscular fatigue.