That is why intensive insulin therapy is not for everybody. Patients unaware of symptoms of hypoglycemia. Patients with advanced diabetic complications such as kidney di sease, eye disease or nerve disease. Patients with coronary heart disease. Children under 13 years of age.
Many patients require an additional insulin injection at bedtime.
In some patients, bedtime NPH can be injected at dinner time along with Regular or Humalog thus reducing the number of injections to three per day. In some patients, Ultralente is given twice a day, before breakfast and before dinner. Humalog Humalog is the preferred short acting insulin in most patients as it starts working within 30 minutes so that you do not have to wait 30-45 minutes after the insulin shot before you can eat as is the case with Regular insulin. Humalog has another advantage in that it is out of your system in about 4-5 hours compared to Regular insulin which hangs around in the body for about 8 hours. Regular insulin at dinner time is usually responsible for low blood sugar in the middle of the night.