And so a cholesterol of 800 is considered very dangerous to you - similarly the trigs of 2400 can pose some problems to your health. The former increases the risk of heart disease, while the trigs can increase the risk also of pancreatitis. And you haven't responded to the two major meds that have reports of success. It is still a judgement call as to the best way to go here. In your combo - the ritonavir is more likely to be the problem drug.
Research suggests that fortovase without the ritonavir has much less of an effect on blood fats.
And push the saquinavir dose up. Another way to get the saquinavir levels up is to use delavirdine instead of nevirapine - since delavirdine has the beneficial effect of increasing the level of these PI's like ritonavir. And may allow you to come off the ritonavir and hopefully have a better lipid profile and similar viral load control. Options to consider. Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material.