They migrate to lungs via the bloodstream. They then enter the airways where, as they make their way up the bronchi, they cause coughing . After traveling up the bronchi, the larva are swallowed. When the larvae are swallowed, they infect the small intestine and develop into adult worms. Adult worms and larvae are excreted in the feces.
Most people have no symptoms once the worms enter the intestines.
However, iron deficiency anemia caused by loss of blood may result from heavy infestation. Improvement in sanitation measures in developing countries is necessary for prevention of infection. This disease may also alter the results of a D-xylose absorption test. The objective of treatment is to cure the infestation, to treat complications of anemia , and to improve nutrition. Symptoms and complications of anemia are treated as they arise.