Don't reach into the cage to take out your rabbit, rather, open the door and let your rabbit come out on its own. Also, don't catch your rabbit and put it back into the cage or it will become a prison, not her home. Rabbits avoid this only when they feel they haven't gotten their fair share of play time outside the cage. Your rabbit should know the cage is a safe haven. Even large cages are no substitute for running time outside of the cage.
Rabbits are joyous and curious and love to run and play.
Keeping a bunny caged most of its life is cruel and will break its spirit. Just remember to never leave a bunny free to roam unsupervised unless all harmful objects are out of reach. They love to examine every inch of every room in search of things to play with, chew or jump on. They will stop at nothing to get past any barricade that impedes their access to other parts of the house. This is further evidence that rabbits crave and enjoy having freedom, something that shouldn't be denied them.