The bacteria usually will not attack muscle or bone. In more advanced cases, major limb amputation is necessary. In addition to the tissue decay, the bacteria causes the rest of the system to go into systemic shock. This may result in respiratory failure, heart failure, low blood pressure and renal failure. Basically, every system of the body can fail as a result of the severe infection and toxicity of the system.
Prompt treatment is essential due to the speed with which the infection spreads.
No major trauma is necessary. In fact, the condition often occurs following minor trauma, or even a bruise or abrasion. As mentioned above, it can occur after surgery. In any case, the symptoms are the same. Often after treatment is sought, misdiagnosis or delayed diagnosis occurs.