The drug doses, that are described here, represent those commonly prescribed. However, drug doses, in individual patients, may differ from those listed here and depend on the patient's clinical situation and the prescribing doctor's preferences. Decisions on the treatment of individual patients with ITP are the sole responsibility of the treating physician. Rarely, patients with chronic ITP will have severe and potentially life-threatening bleeding. The results with each treatment are similar.
Most patients respond within several hours by increasing their platelet count to safe levels.
Usually 50 to 100 grams is given intravenously daily for 1-2 days. Usually 1 gram of methylprednisolone is given intravenously daily for 3 days. An equivalent dose of another corticosteroid may also be used. Rarely, in extreme circumstances, both treatments are given together. In addition to one of the above treatments, platelet transfusions are given as often as necessary until bleeding has stopped.