This is accomplished by proposal applications from the investigator which are approved, with or without limitations, or disapproved. Experimental design, while not a specific focus of protocol review, should be considered to assure valid results from research animals. Formal documentation following the visit should categorize any deficiencies as minor or significant. Chapter I, Subchapter A of the Code of Federal Regulations as the standard. Minimum cage sizes and adequate materials, environmental factors, and accurate identification and record keeping are important.
Occupational health is also important.
The program involves pre-employment physical exams, periodic exams, education, medical care, and consultation with professional staff. An investigation is done, with suspension of a project upon verification of a violation. The persons assigned this job must be knowledgeable of both federal requirements and the institution's animal care program. Institutions and funding organizations may also establish additional husbandry, record-keeping and reporting requirements. Federal agency heads develop internal policies, but must report to USDA annually.