Prednisone suppresses your immune system. This is like re-booting your computer. While prednisone helps many people with ITP, it has some significant side-effects that some patients find difficult to deal with. Most people experience bloating, weight gain, loss of muscle and tone, joint aches and irritability. Be sure to read the Physicians Desk Reference or other helpful web sites for more information.
Prednisone can promote personality changes.
The syndrome is called 'steroid psychosis'. The changes can range from irritability to more severe mood swings. It is important to be aware of the emotional side effects while taking prednisone because it s probably not a good time to make important decisions. Unfortunately if prednisone doesn t bring a sustained rise in your platelet counts, you will be asked to make some very important decisions regarding the next steps of your treatment. If possible, it is wise to begin your research of all available treatments as soon as you are diagnosed.