The research, funded by the National Institute of Child Health and Human Development, appears in two papers published in the May 1 issue of The Journal of Clinical Investigation . About 7 percent of first-time mothers and 1 to 2 percent of mothers having subsequent pregnancies develop preeclampsia. The condition occurs suddenly, without warning, and sometimes in as little as a few hours. Usually, a pregnant woman with preeclampsia develops dangerously high blood pressure and begins excreting protein in the urine. In some cases, the condition may progress to eclampsia, a series of potentially fatal seizures.
Preeclampsia is still one of the leading causes of maternal mortality.
The need to screen for and detect preeclampsia early was one of the original reasons the medical community began recommending regular prenatal visits many years ago. In cases where the condition does not progress to eclampsia, the children born to mothers with preeclampsia may be extremely small for their age or may be born prematurely. This may, in turn, place them at risk for a variety of other complications of birth. Infants born to mothers with preeclampsia may also grow more slowly during infancy than infants whose mothers do not have the condition. Although the high blood pressure accompanying preeclampsia can be treated with blood pressure lowering drugs, the only effective treatment for the condition is immediate delivery.