The ability to treat more plasma volume with reduced risk of depletion syndromes. The monitor controls the flow of plasma, buffer, and eluant through the columns and monitors fluids and pressures for patient safely. The operator can calibrate and continuously monitor the treatment course by means of a display and keyboard, that gives ongoing information about the various treatment steps. The monitor receives citrated plasma from, and returns treated plasma to the cell separator, which in turn delivers the treated plasma to the patient. When plasma is passed through the column, the adsorbent selectively binds immunoglobulins.
Monitor uses two adsorption columns working alternately.
Plasma is passed through one column at a time. After each cycle, plasma is directed from the first to the second column, and the adsorbent in the first column is automatically regenerated. This procedure can be repeated indefinitely until the immunoglobulin level has been sufficiently lowered. ACD-A is used for anticoagulation. Protein A Column is being rinsed with a pH 2.2 eluant solution to remove adsorbed immunoglobulins.