There was one day that Olivia vomited twelve times straight. The doctor took pity on us then and let her have the IV form for the next twenty four hours. Olivia did eventually learn to take Prednisone and keep it down, but she did it her way. She chewed the pills, followed by sips of Coke. Most children, and many adults have a tough time taking medication.
Prednisone does appear to be one of the more difficult pills.
Other than Olivia's method, which I don't recommend, I have seen two other successful methods of getting this drug down. One was mixing crushed Prednisone with a very tiny amount of ice cream and spoon feeding this mixture to the child, and the other was having the child chew up something strongly flavoured and then inserting the Prednisone into the mass of food. This was then swallowed. The food used in this instance was potato chips. I think the potato chips took care of some of the salt cravings brought on by the Prednisone as well as masking the taste of the drug.