While the nasal spray formulation has been shown to be effective in controlling bed-wetting, the nasal route of drug administration may not be ideal for all patients. Nasal congestion may impede absorption of nasal spray. For some patients, the nasal spray can be difficult to administer. A school-age child has on the average 10 upper respiratory tract infections or colds per year, as well as seasonal allergies, all of which can result in nasal congestion. Tablets may be easier and more convenient for patients and families.
Patients previously using nasal spray can begin tablet therapy the next night.
The initial recommended dose is 0.2 mg at bedtime and may be titrated to 0.6 mg to achieve the desired response. The only drug-related adverse event seen in three percent or more of patients was headache. Night-time fluids should be restricted to decrease the chance of fluid overload. Any question regarding a medical diagnosis, treatment, referral, drug availability or pricing should be directed to either a licensed physician or to the product's manufacturer.