Prairie cordgrass is often cut for hay before it becomes coarse. Cutting two or three times a year prevents coarseness. Mowing is not always feasible because high water tables may prevent the use of equipment. The root system has coarse, woody, highly branched rhizomes. Varying germination results have been reported.
Prairie cordgrass is the most abundant grass of low floodplains and wetlands in Indiana.
It occurs on most soil textures from fine clays to silt loams and is somewhat tolerant of alkaline conditions. Prairie cordgrass grows on wet banks of sluggish streams and around ponds. Prairie cordgrass forms stable communities on mesic sites, but as conditions become dry it is eventually replaced by big bluestem. Although prairie cordgrass renews growth rather late, it grows more rapidly than any of the grasses of the prairie. Prairie cordgrass has deep rhizomes which allow it to survive fires.