Make it attractive and easy to read. Reviewers often only have seconds to get the high points. Make the most of those few seconds. Post your resume online. This is a quickly progressing trend.
Many past students report getting jobs from online job postings.
Make sure you are active in this field. However, remember the goal is to get a job not a bunch of time consuming interviews, so try to tailor your resume to those jobs that you really want. Stick to it. Do not give up. It will often be difficult and no fun.