When the immune function is lowered or there is an inflammatory process present, the condition may be worse. This leaves the tissue raw and possibly ulcer-like. Research studies have shown that any stress related activities will alter the immune system. We all have stress and the way that we cope with the stress is an important factor. Python I come off it about a year ago for acne.
Mucotaneous lesions are any lesions that affect the skin or mucous membranes.
They could look like leukoplakia but could also be ulcers. They lesions should begin to disappear with discontining of the accutane. Howerver, it the person stops taking the drug and the reaction abates or disappears it should be some evidence of a cause and effect. Sometimes specimens from mouth lesions are confusing to general pathologists - you may want to have an oral pathologist look at the slides. A dental school in your area would be a good contact.