All I can tell you is that tri-est is a natural form of the estrogens which I get from a compounding pharmacy. I don't know if these dosages vary under different circumstances. Estrone and Estradiol are the ones that may cause most of the risks associated with estrogen use. A two estrogen type of compound is called Bi-estrogen.
Natural progesterone is an important component in menopausal symptom management for many women.
The benefit of using a cream product over an oral form is that you need a much lower dose because it does not have to be metabolized by the liver. Progestins such as Provera are not natural progesterone but a synthetic version which is not chemically equivalent to the progesterone produced by the body. In my case, I have been unable to take any estrogen replacements. Now as I enter menopause, I use Chinese herbs that my doctor mixes. In my case, I have been unable to take any estrogen replacements.