Feedback from pet owners is exceedingly favorable. This is a wide range allowing for some experimentation until seizures are controlled. Bromide levels are measured via blood tests to determine the correct maintenance dose. The drug builds slowly in the blood stream so day by day adjustments will usually have no effect. This practice, however, reveals the biggest problem with potassium bromide therapy.
Potassium bromide is a salt, like sodium chloride, and can cause stomach upset.
Particularly with huge loading doses, nausea is common. There are several things that can be done to lessen the problem. First, the loading dose can be divided into several smaller doses given over the course of the first day or days. Also, large maintenance doses can also be divided and given twice daily if nausea occurs. Some benefit is often seen by giving the dose with food to absorb the initial effect on the stomach.