We are currently seeking participants for the following studies on bipolar disorder. The purpose of this study is to assess whether changes in particular brain regions occur as a result of different mood states. Previous studies suggest that variations in brain function exist in patients with mania, hypomania, or depression. Study participation consists of two one-hour scan procedures, the first being performed while in a mood state, and the second after recovering from the mood episode. The purpose of this study is to assess whether changes in particular brain regions occur as a result of different mood states.
Previous studies suggest that variations in brain function exist in patients with depression.
Study participation consists of two one-hour scan procedures, the first being performed while depressed, and the second after recovering from the depressive episode. This research study is being conducted by Natalie Rasgon, M.D., Ph.D. in the Department of Psychiatry. We will follow women for two years to determine if the use of medications used to treat bipolar disorder change reproductive function, or are associated with a high rate of polycystic ovarian disease. If it is discovered that PCO is more frequent in women who take valproate for bipolar affective disorder than in women who take other medications for bipolar affective disorder, then prescriptions may be changed and this in turn, could benefit women. No treatment is offered in this study, it is an evaluation study.