With the exception of even more rare disorders such as epidermolysis bullosa, for all intents and purposes there are few other common considerations for chronic multiple ulcers in an otherwise healthy individual. Additional studies and indirect immunofluorescence may also be required. Other mucosal sites may be involved and the patient should be examined by an ophthalmologist to determine conjunctival disease. Treatment for all three disorders requires systemic prednisone or a combination of DMDs such as imuran, dapsone, and cyclophosphamide. More aggressive treatment may be required for patients with recalcitrant disease and consultation with a dermatologist or immunologist is advised.
References used by author are available upon request.