Blister formation usually requires thick and rather immobile epidermis, as is found in these areas. In addition, blisters form more easily on moist skin than on dry or soaked skin, and warm conditions assist blister formation. To prevent blisters, you need to minimize friction. For the feet, this begins with shoe selection. Shoes should fit comfortably, with about a thumb's width between your longest toe and the end of the shoe.
Narrow shoes can cause blisters on the big toe and little toe.
A shallow toe box can lead to blisters on the tops of the toes, while loose shoes can create blisters on the tips of the toes. Buy shoes specific for a sport. When trying on shoes, be sure to wear the same socks, insoles, or orthotic inserts that you wear when playing or working out. Try on shoes in the afternoon or evening, because feet tend to swell during the day. Walk or jog around the store before buying them and then wear the shoes around the house for 1 to 2 hours to identify any areas of discomfort.