It is sometimes called coke, toot, and nose candy. In its free-base form it is sometimes called rock, crack, or base. The effects of the drug begin within minutes after entering the system and start with a brief intense euphoric feeling of well-being, which peaks within 15 to 20 minutes and is followed by depression. Cocaine over stimulates the circulatory, respiratory, and central nervous systems. Cocaine interferes with the natural chemical in the brain that stimulate and regulate the firing of nerve cells.
Muscle spasms in various parts of the body can occur.
Over stimulation of the nervous system can cause convulsions which can lead to respiratory collapse and death. This is a question that has had a long history.