An initial increase could be expected since the production of the additives and the blending of the fuels require additional equipment and handling. Prices may vary throuqhout the marketplace. No more so than gasoline. You should take the same precautions for ventilation and fire. It will help.
Oxygenated fuels reduce carbon monoxide emissions.
The gasoline companies are aware of the volume of fuel sold in these areas and have made provisions to have an adequate supply during the winter months. MTBE is generally recommended. Ethanol may be used if specified in the owner's manual. Ask a trained automotive service technician. Besides using oxygenated fuels, there are several things you can do - car pool, organize your travel, bike, or ride the bus.