May be prolonged in severe liver disease or acute overdose. It is considered to be compatible with breast feeding by the American Academy of Pediatrics. Children not to exceed 5 doses daily. Acetaminophen for pain relief should not be used for more than 10 days in adults or 5 days in children. It should not be used for more than 3 days for fever in all age groups.
Rectal absorption is variable.
May cause skin rash andurticaria. Chronic use of high doses has been associated with hepatotoxicity. As an antipyretic, fever would be relieved. References Clinical Handbook of Pediatrics , Wilkins and Wilkins, Philadelphia. Deglin, J. H., Vallerand, A. H., Davis's Drug Guide for Nurses , F. A. Davis Company, Philadelphia, 1997.