They are manufactured in the bone marrow. When bleeding occurs, platelets clump together at the site, swell, and stick to the injured area, acting as a plug to reduce the bleeding. In particular, the difference between the response to ristocetin and the other products is important, because ristocetin triggers aggregation through a different mechanism than the other products. Obtaining a blood sample from some people may be more difficult than from others. Stored platelets after blood donation.
Platelets are a very important component of blood.
These tiny particles plug small holes in capillaries and vessels caused by the damage of everyday living. Platelets can be separated from blood and given to individuals who have low platelet counts and are at risk for serious bleeding.