To be eligible, volunteers must not be taking medication to control their blood sugar. Participants will receive a physical exam, study tablets and relevant laboratory tests at no cost. Individuals whose diabetes is poorly controlled by pills may require insulin therapy. Volunteers must be between the ages of 30 and 70 to participate. They will receive a physical exam, study medications and relevant laboratory tests at no cost.
Monetary compensation is provided.
Volunteers must be postmenopausal women age 35 and older who are at increased risk for developing breast cancer. In STAR, the drugs tamoxifen and raloxifene will be compared for their effectiveness in reducing the occurrence of breast cancer in postmenopausal women. Participants will receive either tamoxifen or raloxifene for five years. Anemia Volunteers are needed to participate in a study to evaluate the effectiveness, ability to improve the quality of life, and the safety of the drug Procrit when taken once a week for the treatment of anemia of chronic disease in the elderly. Procrit is a drug approved by the FDA but is investigational in this setting.