In the past years the student body has grown from the original 199 to the present 575 and the number of alumnae to 7730. The successful achievement of Mercy's first graduating class immediately placed the high school on the list of secondary schools accredited by the University of California. In 1958, Mercy High School became a charter member among schools accredited by the Western Catholic Education Association. Mercy's dedication to excellence in education is witnessed by the approval of these regional accrediting agencies, reflecting the success of its graduates. The school is also a member of the National Catholic Education Association.
Mercy offers a four-year college preparatory program.
Advanced Placement and Honors courses in English, mathematics, science, foreign language and history are available to qualified and interested students. Special placement in various disciplines is based on student need, determined by the assistant principal for academics, department chairs and counselors. Religious education classes are an important component of the Mercy curriculum. The fine arts program is one of the most diverse in the Bay Area and the athletic and speech programs have received state level recognition. Mercy's student government program has received the highest award from the California Association of Student Councils.