All medicines can have some side effects, but not all people get them. Some people experience different side effects than others.
Most side effects occur in the first few hours of treatment and gradually go away.
Aspirin and ibuprofen can produce stomach irritation, so be sure to take these drugs with fluids or food. Also, high doses of aspirin can cause a ringing in the ears. To help prevent constipation, drink lots of water, juice and other liquids and eat more fruits, vegetables and foods high in fiber, such as whole wheat bread. In addition, you may want to talk to your doctor or nurse about using stool softeners or a laxative agent. Exercise, including walking, helps prevent constipation.