As the name implies, loose connective tissue consists of a loosely woven mix of fibers, cells, and ground substance. Loose connective tissue therefore possesses randomly arranged protein fibers with abundant intercellular spaces. Fibroblasts can often be seen adhering to newly formed fibers . Most are neutrophils or lymphocytes .
Plasma cells are highly efficient producers of antibodies.
Although most are located in lymphatic tissues like lymph nodes, they do occur in loose c.t. areas. Plasma cells, like lymphocytes, possess a well-defined, spherical shape with rounded nuclei . Mast cells release histamine and heparin. These chemical agents induce the vascular responses that cause inflammation. Mast cells are fragile, granular cells that can rupture during tissue preparation and staining.