In MG, even though there is nothing wrong with the neuromuscular junction, somehow the immune system gets triggered to attack it anyway. The antibodies bind to the muscle's membrane and initiate a series of events that destroy the membrane and prevent ACh from binding. If ACh can't bind to the muscle, the muscle won't contract. MG is sometimes associated with other autoimmune diseases, including rheumatoid arthritis and thymus abnormalities. Rheumatoid arthritis leads to chronic inflammation of the joints, especially the hands.
Most patients have other symptoms as well, in which case they have generalized myasthenia gravis.
Congenital MG is believed to have an inherited genetic basis. Find a neurologist near you. Join a live chat or threaded forum. Visit our medical store for your medical supply needs. Find neurology related clinical trials through Veritas Medicine .