Usually offered in even years. Applications of these methods to interesting biologically relevant problems will be discussed. Usually offered in odd years. This course will include lectures and student seminars and is open to senior and graduate students. The course will focus on the structure and mechanisms of redox enzymes.
Organisms use three different classes of redox centers in enzymes.
All three kinds of enzymes will be discussed. Usually offered in even years. Many important biological phenomena depend on the binding of specific DNA sequences by regulatory proteins. The course will survey work on the structure of sequence-specific DNA binding proteins and their complexes with DNA, to study the mechanisms of specific DNA binding. The biological significance of different binding mechanisms will also be discussed.