Decreases platelet adhesiveness. Metabolized by the liver. Reversal with IM vitamin K and fresh frozen plasma. See figure 1 Aspirin Inhibits the entire prostaglandin pathway by irreversibly acetylation cyclooxygenase. This inhibits prostacyclin and thromboxane production.
Net result is that there is an increase in platelet cAMP which decrease platelet aggregation.
When used with aspirin there is an enhanced effect. Streptokinase nonenzymatic protein produced by group C beta hemolytic strep. Activate plasminogen in a two step process. Urokinase Enzymatic protein made by the human renal parenchymal cells grown in tissue cultures. Activate plasminogen directley to produce plasmin.