Typographical or Grammatical Errors Seems obvious, yet many, many Web pages contain common spelling and grammatical errors. Use spelling and grammar checkers to make sure your copy is first-rate. These are self-serving words that turn off readers. Many older browsers don't support frames. Many search engines don't index them properly.
Many frames require scrolling to read the text and activate links.
Frame scrolling bars take up precious real estate. It just wastes their time and could possibly frustrate or annoy them. Every page on your site should have a purpose or reason why it's there. This should be obvious, but broken links are all too frequent. Broken links are annoying, frustrating and unprofessional.