LCIS is characterized microscopically by a solid proliferation of small cells. Since there is a reported risk of bilaterally in this disease, some investigators have recommended treatment with bilateral simple mastectomy with immediate breast reconstruction. If watchful waiting is elected, lifetime observation is mandatory since the increased risk of breast cancer persists indefinitely. Tubular carcinoma is also known as a well-differentiated carcinoma. The prognosis is considerably better than for invasive ductal carcinoma.
Medullary carcinoma is characterized by a prominent lymphocyte infiltrate.
Patients with medullary carcinoma tend to be younger than those with other types of breast cancer. The prognosis is also believed to be better than for invasive ductal cancer. Inflammatory Breast Carcinoma is characterized by diffuse skin edema, skin and breast redness, and firmness of the underlying tissue without a palpable mass. Inflammatory breast cancer carries a poor prognosis. Paget's disease of the nipple is a rare form of breast cancer that is characterized clinically by eczematoid changes of the nipple.