Unlike ova which are ready made and only maturing within the ovary, sperm cells are continually being produced by cell division, and dividing cells are the ones most likely to be affected by carcinogens. Carcinogens would also be expected to have effects on the dividing cells of the fetus, but it may be that the predominant effect would be to cause very early spontaneous abortion and reabsorption of the fetus. Also there might be metabolic inactivation of the carcinogens in the placenta. There is evidently much that is still unknown about this finding. Treatment comprised preoperative chemotherapy, surgery, and postoperative chemotherapy.
Many regimens produce undesirable sedative effects or side reactions.
No child had persistent behavioral abnormalities and all had amnesia for the procedures done.