Two histological stages of chronic liver disease are fibrosis and cirrhosis. Fibrosis is seen as scar formation in the patient s liver. The scars occur as the liver tries to repair damaged tissue. Cirrhosis is a condition where the liver becomes permanently scarred. Cirrhosis interferes with normal liver function, and many times, the patient is symptomatic.
Necrosis is dead liver cells.
Fibrosis Fibrosis is an accumulation of fibrous tissue resulting from an imbalance between several types of liver cells. As liver cell structures change, the function of the liver is altered. Fibrosis is common to several chronic liver diseases, as it is a sign of hepatic injury. A diagnosis of fibrosis is usually determined with a liver biopsy. The clinical feature that is most apparent with fibrosis is portal hypertension.