Biopsy is often performed to rule out other conditions. The histologic features of lichen sclerosus characteristically show inflammatory changes at all levels of the skin. An estimated 5 percent of cases of lichen sclerosus in women progress to vulval squamous cell carcinoma. Treatment with potent topical steroids provides relief of symptoms. Clobetasol proprionate 0.05 percent may be used twice daily for up to three months, then tapered, depending on patient response.
Patients also require significant information and support services.
Analgesic and other symptomatic treatments, such as stool softeners, local emollients and lubricants, may also be indicated. Male and female patients may require surgery to correct scarring deformities, and all patients should be continuously monitored because of their risk of developing malignancy. M.D. Powell JJ, Wojnarowska F. Lichen sclerosus. A person viewing it online may make one printout of the material and may use that printout only for his or her personal, non-commercial reference.