Reduction of imines or amides-previously covered. Nucleophilic substitution using NH 2 or amines- only works well for making primary amines. Use an excess of ammonia. Primary amines 4. Nitrous acid is an unstable compound which is prepared just prior to use.
Nitrous acid reacts in various with all types of amines.
Some N-nitrosoamines are potent carcinogens. They may be produced in the human gut when sodium nitrite from prepare meats is injested. Primary Aliphatic Amines-produce a mess of products resulting from the carbocation formed in the reaction. Primary Arylamines form arenediazonium salts. These arenediazonium salts are very useful in forming other aromatic compounds.