Ensure that he's accountable for his actions, especially homework and commitments to friends. Let him see that adults feel vulnerable too. Catch him doing smart things whenever you can. Tell him he's special and that you love him just the way he is. When he does something courageous, tell him you're proud of him.
Role play ways to handle tough situations at school.
Explore realistic career options with him. Be available when he wants to talk and validate his feelings of being different. Provide a safety net for him so that he feels secure enough to take risks like trying out for team sports, looking after a neighbour's pet, or spending two months' allowance on a toy he's been wanting. Make sure he understands his rights and responsibilities. Let him experience the joy of helping someone else.