He had also been exposed for a prolonged period to carbon tetrachloride. In the last few months he became jaundiced and died from liver failure. At autopsy the liver was enlarged, and mottled yellow to red and grossly resembled chronic passive hyperemia. The kidneys were large and swollen. The liver had grossly a yellow mottled appearance.
Regeneration is minima or absent.
During the next four hours the pain became more severe and localized to the right lower quadrant of the abdomen. He became nauseated and vomited. The appendix was removed, it was enlarged and the lumen was distended. Serosal vessels were prominent and engorged with blood. The serosa was dull and covered over its distal half by a yellowish, soft, friable coating.