Paul Thompson's Research Publications 3D Maps of Cortical Surface Variability and Sulcal Asymmetries in Schizophrenic and Normal Populations 5th International Conference on Functional Mapping of the Human Brain Narr KL, Sharma T, Moussai J, Zoumalan CI, Cannestra AF, Thompson PM, Toga AW Laboratory of Neuro Imaging, Dept. These maps are made using new mathematical and computational strategies for cortical mapping and for creating population-based brain atlases.
Neuroanatomic abnormalities are characteristic in schizophrenic populations.
Briefly, parametric meshes modeling cortical surfaces are translated from spherical tensor to planar maps retaining 3D position information encoded in color. A rectangular grid placed over each planar color map allows averaging of grid-points from the same cortical locations using a flow field. Finally, group averaged cortical models are translated back into 3D retaining information about individual cortical patterns. Variability was increased in superior extents of the temporal sulci including the Sylvian fissure. This was more extreme in right perisylvian cortices and in frontal and intraparietal sulci in patients.