N.Vouilloz and A.Martinez Arias. Nicole Vouilloz and Alfonso Martinez Arias Dpt. The Notch gene encodes a single transmembrane receptor involved in cell interactions during development. The best characterized function of Notch is in the process of cell fate suppression termed lateral inhibition, which restricts cell fates to a few cells from within a population of cells competent to express that fate. Analysis of this function has revealed a role for Notch in the establishment of planar and tissue polarity which will be presented and discussed.
Notch is required for wingless signalling in the epidermis of Drosophila .
A functional analysis of Notch mutations in Drosophila .