The target antigens are constituents of hemi-desmosomes which hold the epidermis to the dermis. Cicatricial pemphigoid is a clinical subtype that differs from the more common bullous pemphigoid because skin blisters are not present and mucosal lesions predominate that heal with scarring . The rare variants include pemphigus herpetiformis and IgA pemphigus. A molecle derived from two or more amino acids. In the human body they can be obtained by the partial digestion of proteins.
Proteins are essential elements of all living cells.
A site on the surface of a cell which in a lock and key fashion fits into a complementary site on another cell or protein, as in the binding of an antibody to an antigen . Involving the entire system or body. Medications taken orally are systemic because they are distributed to the entire body. A type of lymphocyte involved in cell mediated immunity that matures under the influence of the thymus. T cells destroy cells marked by antibodies or expressing specific antigens.