Then cross your fingers. The last agent on her long, alphabetized list agreed, and sold the novel within a week. It's easier to publish nonfiction. Every publisher and agent will tell you the same thing. It used to be traditional that more fiction was sold than nonfiction.
Most aspiring authors dream about publishing novels.
Her first book was a biography of Ruth Graham, wife of evangelist Billy Graham. Take one step at a time. This can include both subject matter and publisher. Janet Evanovich wanted to write funny mainstream novels, but couldn't find an agent or publisher willing to take a chance on her. So she began writing romance novels, which is perhaps the easiest genre for aspiring writers to break into.