Contact Multimedia Gallery Click on the thumbnail images below to display the full-size versions. This model shows propagation of a normal wave of excitation in the model.
Membrane potential is color coded, as shown by the color bar on the left side of the image.
In this color code, red corresponds to electrically unexcited cells and blue corresponds to electrically excited cells. This ECG signals shows a portion of the normal QRS and T wave complexes. This model shows electrical propagation in a computational model of the heart in which biophysical changes occurring during heart failure are modeled. Specifically, the transient outward K current Ito1 and the instantaneous outward K current Ik1 were down-regulated. The resulting action potential prolongation produced an early after-depolarization in a region of the heart model.