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Ritonavir increases blood levels of indinavir and allows for a twice daily dosing.
The study will be conducted in Vancouver, Montreal and Toronto. A total of 165 participants will be enrolled and followed over a period or three years. During this acute or primary phase of infection, the blood contains many viral particles that spread throughout the body, seeding themselves in various organs, particularly the lymphoid tissues. This acute HIV infection often passes unrecognized, but may be present as a flu-like syndrome, especially in the weeks following infection. The diagnosis is made by demonstrating the presence of the virus itself in the blood, often before any antibodies may be present.