The researcher, John W. Dean III, D.D.S., Ph.D., is an associate professor in the UConn dental school Department of Periodontology. His investigations are part of a pair of national studies.
Periodontal disease is a progressive disease affecting the gums and the jawbone.
If left untreated, periodontal disease will eventually cause the teeth to be lost. Treatment involves deep cleaning or root planing by a professional, and regular flossing and brushing of the teeth and gums thereafter. The first of Dr. Dean's investigations is helping to determine if a small dose of antibiotics may inhibit the production of an enzyme that contributes to periodontal disease. Collagen allows the gums and jaw bone to hold the teeth. Thirty-five patients are involved in Dr. Dean's investigation with Periostat, which will run for nine months.