I know this is hard for non-economists to believe, but orthodox economics essentially ignores technological change. But once you allow technological change into the model, you've got unpredicatble complexity. For example, even as GNP rises, changes in travel patterns like telecomuting and air travel whittle away at automobile demand. Car makers keep substituting more and more aluminum and plastic for steel. Across the economy, new technologies keep changing the relative value of alternatives.
Precise predictions become impossible.
But rather than admit that, orthodox economists choose to ignore technological change. Bionomics, by contrast, pays primary attention to technological evolution. Yes, of course, and there is a consistent pattern to these differences. There is a built-in bias toward intervention. If, on the other hand, you believe the economy is a like a rainforest, you'd be very cautious about intervening.