Georgios Blatzas Abstract Adrenal involvement is a relatively frequent event in systemic histoplasmosis.
Most cases involve bilateral, homogeneous enlargement of the glands.
The present case had a unique clinical presentation as a unilateral cystic adrenal mass. To the authors' knowledge, this type of lesion has not been associated with adrenal histoplasmosis before. The diagnosis was confirmed at histopathology.