What causes the problem is this. About half our body fat is stored in individual cells just under the skin, and as more fat is packed into the cells, they swell. When these compartments get large enough, they become visible through the skin. Also, as our skin gets thinner and less flexible with age, the puffed up fat cells are easier to see. Typically, the effect is more noticeable in women than in men since women have a greater concentration of stored fat around the hips, thighs and buttocks.
Men also tend to have less total fat, and they have a thicker skin to cover the swollen cells.
The only help here is weight loss, with diet and exercise. No exercise can remove fat exclusively or principally from one part of the body, as some product pitches suggest. Until more research on Cellasene is done, peer reviewed, and published , save your money.