The lab work involves rats with a variety of lung injuries that are analogous to ARDS, the goal being to optimize responses to surfactant therapy using a newly designed pulmonary surfactant that is resistant to inactivation. Pediatric Research, Vol. 45, No. 4, Part 2, April 1999. Hydrophilic polymers added to surfactant enhance treatment of lung injury by reducing surfactant inactivation. 159, No. 3, Part 2, March 1999.
Nonionic polymers reverse inactivation of surfactant by meconium and other substances.
Amer J of Resp and Crit Care Med. Amer J Respir Crit Care Med.