The PL-PSDA is an integrated, automated system for the rapid determination of particle size distribution of colloidal dispersions. The automated features and user friendly software combine to deliver remarkable ease of operation which, together with the high resolution of the technique, provide an instrument suitable for both quality control and research applications.
Particle size can have a fundamental effect on the physical properties of colloidal dispersions.
Fractionation techniques, including packed column HDC, offer advantages over non-fractionation techniques for particle sizing in that the method produces information about the average particle size and the distribution of particle size. An autosampler enables multiple sample vials to be loaded and sampled for continuous, unattended operation. The sample under investigation, and a small molecule marker solution, are introduced into the system via a two position, electrically actuated valve such that the eluent flow is not interrupted. The PL-PSDA contains a separating 'cartridge'. The UV detector response is used to calculate the concentration of particles of different size present in the sample.