Wool socks tend to whisk moisture away from the skin and may be helpful. Many clinicians find that topical antibiotics are effective, even without the preceding steps. They are certainly easy to use and well accepted by patients. Twice daily applications of erythromycin or clindamycin are effective. Either solutions or gel formulations may be used.
Oral erythromycin is another option.
Effective treatment of pitted keratolysis clears both the lesions and odor in 3-4 weeks. The goals of pharmacotherapy are to reduce morbidity and prevent complications. Antibiotics - Empiric antimicrobial therapy must be comprehensive and should cover all likely pathogens in the context of the clinical setting. Inhibits bacterial growth, possibly by blocking dissociation of peptidyl tRNA from ribosomes causing RNA-dependent protein synthesis to arrest. Many clinicians find topical antibiotics to be effective, even without other measures.