Many patients develop edema during pregnancy and since sodium bicarbonate will aggravate edema, it is not a good choice. Antacids can be used indefinitely if they are only taken occasionally. However, when they are necessary several times a day, medical attention is required. Excessive antacid use in the short-term may indicate an underlying disorder that needs different care. The long-term, heavy use of any antacid can produce medical problems and should not be done without a physician's input.
Most antacids produce only minor side effects, especially if they are used infrequently.
Minor side effects are usually relieved by reducing the dose or frequency. The major concern with sodium bicarbonate is the very large amount of sodium which may worsen blood pressure, heart disease or edema of the legs and feet. Antacids are one of mankind's oldest friends. If you develop occasional heartburn or indigestion, you take an antacid and get instant relief. No house should be without an antacid.