Chronic priapism, male pattern of hair loss, epididymitis and bladder irritability have been reported. Hirsutism, hoarseness or deepening of the voice, clitoral enlargement, alteration of libido, menstrual irregularities and male-pattern baldness may occur. The voice change and clitoral enlargement are usually irreversible even after prompt discontinuance of therapy. The use of estrogens in combination with androgens will not prevent virilization in females. Fasting blood sugar and glucose tolerance test.
Free thyroxine is usually normal.
Altered tests usually persist for 2 to 3 weeks after stopping anabolic therapy. Increased or decreased serum cholesterol. Supression of clotting factors II, V, VII, and X. Increased creatine and creatinine excretion lasting up to 2 weeks after discontinuing therapy. Decreased 17-ketosteroid excretion. Remission may not occur before 3 to 6 months of therapy.