As a complement to item 1, a pre-conjugate vaccine incidence baseline would be established if disease surveillance were established prior to availability of pneumococcal conjugate vaccine for infants. Individual case information is then obtained by local health department and infection control nurses on an ISDH provided data collection form. Fifty-four cases had S. pneumoniae isolated from two separate sterile sites. The following report describes the cases and isolates from both the 1999 and 2000 dataset. As can be seen in Figure 1, pneumococcal disease has a seasonal pattern of high incidence in the winter and early spring months.
Pneumococcal disease is a disease of the very young and the elderly.
Specimen Source Isolates were obtained from nine different sterile sites in 1999-2000. Figure 3 shows the percentage from each site based on the 745 sterile sites from which S. pneumoniae was isolated in 1999 and the 475 sites in 2000. Drug Resistance Drug Resistance has become an emerging world problem in the treatment of S. pneumoniae invasive disease. In the U.S., drug resistance has increased substantially in the last 15 years. As can be seen in Figure 4, numerous reports have been received from many counties, while reports have not been as forthcoming from other counties.