Medication and psychotherapy together, particularly cognitive-behavioral therapy, seems to be the most helpful treatment so far. Signs of Depression Feeling down and sad, and it doesn t seem to go away. Crying more than usual. Feeling very tired and not having much energy. Loss of self-confidence and not feeling good about yourself.
Life seems meaningless.
Difficulty concentrating and remembering things. Changes in sleeping and eating habits. Loss of interest in things that you normally like to do. Withdrawing from friends, family, and activities. Thoughts of death and dying, perhaps even suicide.