Complaints related to joint problems are characterized here. Pain is a significant problem and seems to become worse with time. On the other hand, instability seems to improve with age and flexion contractures and stiffness are common after 40. Hypermobile joints are essentially universal. These numbers represent the percentage of patients who have had at least one dislocation.
Most patients report multiple recurrences for a specific joint.
Cramping of muscles, particularly at night, was a very common complaint. Many patients found relief with quinine. Weakness was also very common. Bracing was somewhat effective for instability. Cutaneous manifestations varied with type.