The rate of graft thrombosis should not exceed 0.5 thrombotic episodes per patient year at risk. The rate of thrombosis is largely determined by the presence of unrecognized hemodynamically significant stenosis. By detecting and treating stenoses early in patients with synthetic grafts, as outlined in this set of guidelines, the Work Group believes that the rate of graft thrombosis can be reduced significantly.
Native accesses have a much lower thrombosis rate compared to prosthetic grafts.
The Work Group concluded that a thrombosis rate in native fistulae of 0.25 episodes per patient year is achievable.