The average adult length is about 2.2 inches. Males are slightly smaller than females. The dorsal surface of the body has rounded warts. The warts size is between those of the Great Plains toad and the boreal toad. The cranial crests fuse medially to form an elongated boss, a ridge with a median groove, or paired ridges.
Postorbital ridges are instinct or absent.
The tympanum is round, smaller than the eye. Background color is gray, dark brown or greenish with small dark blotches and an indistinct median line. Some toads have well defined light lateral strips. Males have a darker throat and the belly is usually spotted. The Wyoming toad is morphologically and genetically distinct from other toads.