He fought to win his point, long after his ministers and Parliament had given up on the war, but magnanimous in defeat, George William greeted John Adams, the new U.S. Ambassador, and welcomed the United States of America as an independent power. This did not mean that George relinquished his struggle with his ministers. On the contrary, he fought for his rights as king, in constant conflict with Pitt and his ministers, as long as he occupied the throne. After the French Revolution, he achieved a strong and widespread popularity as the symbol of resistance to France. The tragedy of George's madness is known to all.
Heme is manufactured by the bone marrow and liver to carry oxygen in hemoglobin and hemoprotein.
Porphyria, of the type George had, caused neurological and intestinal symptoms as well as severe pain. Finally in 1811, after the death of Princess Amelia, his favorite child, he succumbed entirely to his madness. Parliament called for a regency, and named his eldest son, George Augustus Frederick, with whom he had a miserable relationship, Regent. George III lived for another nine years in insanity and blindness. George Augustus Frederick, the Prince Regent, was the first and only member of his line to be distinguished by wit and a taste for the arts.