Don't make your work friends your life. Keep in touch with people you knew before you became a NetSlave. See a therapist. It could be Big Brothers, a charity wiring schools for the net, anything which gets you away from the office and out into the world. Reading is an excellent way to learn, enrich the experience of life and forget your problems for a while.
Education is a great way to meet people who share other concerns in life.
That way, you never have to work in an office again, see people you don't want to and can spend all day in bed with your French mistress. Buy the book or hear the authors read excerpts at MP3.COM .