Compare the bioregional map with a congressional map overlay. See for yourself. See in what political structural context 'accidents' and health issues are at their worst. This should appeal to any Green, any independent swing voter, and even any Democrat or Republican who are disgusted with their unrepresentative parties on the ground and want democratic competition between the parties. As well as someone who can tell them why their children who are born without belonging to any political party, are born with brain cancer.
Most bioregional strategies are entirely local.
They require a way to extrapolate how to organize larger levels of politics on this secure base of geographic representation, dealing with the sociology of risk and pollution, etc. Organize the watershed.