The lessons below are somewhat graphics intensive and will be disappointing if your browser is not Java-enabled . The pancreas is divided into lobules by connective tissue septae. Lobules are composed largely of grape-like clusters of exocrine cells called acini , which secrete digestive enzymes. Exocrine secretions from acini flow successively through intercalated ducts , intralobular ducts , interlobular ducts and finally into the duodenum through the main pancreatic duct . Embedded within the pancreatic exocrine tissue are Islets of Langerhans , the endocrine component of the pancreas.
Islets contain several cell types and are richly vascularized.