Know how arboviruses are transmitted . The disease syndromes caused by groups of arboviruses and their transmission. How arboviruses get to the brain. The virulence characteristics of arboviruses and the host response. The pathogenesis of antibody mediated enhancement.
Flaviviruses have different tissue tropism.
They all cause hemorrhagic fever. They all cause meningoencephalitis. They all infect endothelial cells. They all cause hepatitis. A vector is not always necessary for human arboviral disease.