However, proteins fold into distinct secondary and tertiary structures that allow amino acids that are far apart in the primary sequence to be near each other in the native protein. Prostaglandins are a class of fatty acid derivatives with a variety of extremely potent actions on vertebrate tissues. Prostaglandins are responsible for producing fever and inflammation and its associated pain. They are derived from the 20-carbon fatty acid arachidonic acid in a reaction catalyzed by the enzyme prostaglandin endoperoxide synthase. Focusing here on the first two columns, determine the V max and K M of the enzyme.
Graph paper is on the next page.
Please show all of your work and your labeled graph. You need to do a Lineweaver-Burk plot here. By inhibiting the synthesis of prostaglandins, ibuprofen reduces inflammation and pain. Using the data in the table above, determine the type of inhibition that ibuprofen exerts on prostaglandin endoperoxide synthase. Again, please show all of your work.