The advent of newer azole agents provides a significant and favorable impact on disease prognosis. Some of the patients develop overt disease 30 or more years after leaving the endemic regions. Approximate distribution of the disease in North, Central, and South America, based on case reports. In situ localization of T lymphocyte subsets in human paracoccidioidomycosis. Medicine is a constantly changing science and not all therapies are clearly established.
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