P is a blood product made from pooled human plasma. It contains Factor VIII, Von Willebrand Factor VII, human albumin, amino acetic acid, sodium chloride and sodium citrate.
P is made from human blood.
Therefore the presence of infectious agents, including unknown diseases, cannot be excluded. Their plasma is not used if any screening test is positive. P is pasteurized by heat treatment in an aqueous solution at 60 C for 10 hours. In a clinical study no cases of hepatitis B or hepatitis C transmission occurred. At present, there is no test to screen out CJD-associated donations, nor do current viral inactivation methods eliminate the abnormal prion protein.