Two chapters deal with the computational side of obtaining a structure. The first one describes all the methods and tricks necessary to process the raw data into NMR spectra in such a way that a maximum of information is combined with a minimum of artefacts. The second explains the various approaches to calculate the structure of the protein from the available NMR data. Finally, in one chapter a case study is presented, giving an overview of the structure determination of a small protein. NMR on macromolecules has become too wide a field to be covered by a single book.
Many excellent books are available, describing for example only practical aspects or theory.
Therefore, any new book should have a clearly defined subject and public. This appears to be lacking in Protein NMR techniques. The range of subjects is rather wide and, while some chapters are concise introductions into a particular subject, others are elaborate and sometimes rather technical reviews, more suitable as a reference for specialists than as an introduction. So, the book as a whole is not very suited as an introduction into protein NMR for the biochemist who considers to take the plunge into NMR structure determination. Instead, it should be considered a collection of excellent reviews which forms a useful contribution to the book shelf in any NMR lab.