Altered binding of 125 I-labeled calmodulin to a 46.5 kilodalton protein in skin fibroblasts cultured from patients with cystic fibrosis. Bryostatins activate protein kinase C in intact human platelets. Phosphorylation fails to activate chloride channels from cystic fibrosis airway cells. Processing of angiotensin peptides by NG108-15 neuroblastoma X glioma hybrid cell line. The non-peptide angiotensin II antagonist DuP 753 is a potent stimulus for prostacyclin synthesis.
Human astrocytes contain two distinct angiotensin receptor subtypes.
Subtype 2 angiotensin receptors mediate prostaglandin synthesis in human astrocytes. Identification and regulation of angiotensin II receptor subtypes on NG108-15 cells. Characterization of angiotensin receptors mediating prostaglandin synthesis in C6 glioma cells. Alterations in prostaglandin production in spontaneously hypertensive rat smooth muscle cells. Differential regulation of prostaglandin synthesis by angiotensin peptides in porcine aortic smooth muscle cells.