Everybody pretends to be happy. Outwardly people live in a paradise by virtue of cultural achievements and civilization. But inwardly people live in fear and doubt under Satan's rule. It is remarkable to know the fact that each time the civilization rose up to its peak, the world was utterly corrupted and the people became ungodly. As a result, people do not know how to pray.
Prayer is, in essence, spiritual breathing.
In prayer we lay all our anxiety and burden of sin on Jesus. In prayer we can rejoice in God, believing that he will care for us. But those who do not pray are all like asthma patients. Modern times are full of asthma patients or mental patients. Look at verse 24.