Your transplant team will determine your proper dosage based on your weight, blood levels, other laboratory tests, and the possible side effects of Prograf. On a day when your Prograf level is to be measured, do not take your morning dose until your blood has been drawn. Prograf is usually taken with other immunosuppressant medications such as prednisone, azathioprine, or mycophenolate mofetil. Many commonly used medications interact with Prograf. Check with your transplant team before starting any new medications.
Prednisone is a corticosteroid that helps prevent and treat rejection of a transplanted organ.
Another corticosteroid, Solumedrol, may be given at higher doses by vein to treat rejection. Some patients may be taken off prednisone but other patients may be required to take it for their entire lifetime. Prednisone can be hard on the stomach. If prednisone is taken once a day, it is best to take it at the same time each morning. Your transplant team will determine the proper dosage for you according to your weight, how well your transplant is functioning, and the length of time since your transplant.