Be sure to use real quotation marks, not neutral ones. The same goes for apostrophes, of course. Underlining is the work of Satan. Or at least of typewriters. Just say no.
Italics look so much nicer.
And let's not even talk about abominations like outline or shadow. Em and en hyphens. Spaces after periods. When typesetting always put one space only after a period. That putting two spaces after a period thing is another typewriter abomination.