First, carbon monoxide may damage the inner walls of the arteries, encouraging the buildup of fat in them. Over time, this causes the vessels to narrow and harden. Nicotine may also contribute to this process. Nicotine is rapidly eliminated by the kidneys and remains in the body for about two hours. The rate of excretion depends on the pH of the urine.
Excretion is slower if the urine is alkaline.
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