Radiculoneuritis, mononeuritis multiplex. Diffuse peripheral sensorimotor neuropathy. Myopericarditis with ST-segment changes, arrhythmias. Syncope, presyncope or palpitations. Valvular involvement rare.
Onset can be weeks to years after tick bite.
Varies from migratory musculoskeletal pain to overt inflammatory arthritis. Asymmetric oligoarticular intermittent pain and swelling, usually of large joints, such as knee. Later manifestations years after tick bite. Acrodermatitis chronica atrophicans. Mild axonal polyneuropathy.