Unsupervised, these diets can be very dangerous, and fatalities due to cardiac-related factors have been associated with them. Jaw wiring and in-hospital supervised starvation also have been used to treat this disease. Nevertheless, research continues in this area, and a recent finding suggests that the seratonin uptake inhibitors may promote weight loss in some individuals. Morbidity and mortality with this procedure are less than with the above procedure, but are still real considerations. The recidivism rate, regardless of the intervention, is high.
Exercise is essential to increasing energy expenditure and promote physical fitness.