Frequently, facial nerve paralysis occurs in severe cases. Biopsy of the ear canal is necessary to differentiate the granulation tissue typical of this condition from a malignant neoplasm. Osteomyelitis spreads along the base of the skull and may cross the midline. Treatment Surgery is usually not helpful or necessary. IV therapy with a fluoroquinolone or with a combination of an aminoglycoside and a semisynthetic penicillin results in complete resolution in most cases.
Longer therapy is required for extensive bone disease.
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