It usually shows up as tingling, numbness, or a sharp burning sensation in the feet, legs, or hands. The nerve damage is usually temporary and will go away if you stop taking ddC, or reduce the dose. If you continue to take ddC after nerve damage shows up, it may become permanent. See Fact Sheet 553 for more information. Pancreatitis is an inflammation of the pancreas, a large gland located behind the stomach.
Pancreatitis can be fatal.
If you are taking ddC and have sharp pain near your stomach, back, or sides, with nausea and vomiting, you should stop taking ddC immediately and call your doctor. Blood levels of ddC may be decreased by antacids or cimetidine. Blood levels of ddC may be increased by aminoglycosides, amphotericin B, foscarnet, or probenecid. Several other medications can make the side effects of ddC worse. Be sure your doctor knows about all the medications you are taking.