It won't affect your long term expectation one way or the other, but you're going to waste a lot of time when you could be playing. If this can be applied to video poker, I will be able to give these players a real answer. I eagerly opened to Don's article and found just about what I should have expected. The article does not address the question of when to quit playing at all. Instead, Don gives us a mathematically sound discussion about when to give up on back-counting a shoe and move to a different blackjack table.
Many people attempt to apply a similar technique to video poker and slot machines.
They watch for a machine that has been played heavily without hitting a jackpot, or they ask the bartender or change person for that information. In blackjack, the cards that have already been dealt from the shoe tell us what remains in the pack, so even though those remaining cards are dealt randomly, we have information about the changed probabilities. In video poker, however, the complete deck is shuffled before each hand, so we can not garner any information from the game's history. The probability of that machine hitting a royal on the next play is exactly the same as it was an hour ago or will be tomorrow. So, as I have said many times, there is no mathematical method to decide when to quit playing.