For mild inflammation, nonsterodial anti-inflammatory medications are helpful. Corticosteroids, the single most important drugs to treat SLE, must be used judiciously. Bone protection is important when steroids are used. Anti-malarials such as hydroxychloroquine reduce SLE activity and are helpful for the skin and joints. More severe SLE requires immunosuppressive drugs such as azathioprine and cyclophosphamide.
Researchers play a critical role in both basic science and clinical investigation of the disease.
Rheumatologists educate other physicians about the disease and its treatment.