Bacterial culture and antibiotic sensitivity testing help the veterinarian select an appropriate antibiotic. Unfortunately, even though the signs of infection can be relieved, the causative bacteria cannot be eliminated. Rabbits and rats harbor at least one of the bacteria known to cause pneumonia in guinea pigs. Therefore, it is wise not to house these animals with or near guinea pigs. Signs include lethargy, inappetence, and difficulty in breathing.
Numerous bacteria can cause infections of the gastrointestinal tract of guinea pigs.
Some of these bacteria are introduced on contaminated greens and vegetables or in contaminated water. Intestinal infections can manifest themselves as sudden death without prior signs, or as a more lengthy period of illness characterized by lethargy and marked weight loss. Diarrhea may or may not be noted in either case. A veterinarian will recommend aggressive antibiotic therapy and appropriate supportive care. A bacterial culture of the patient's stool and antibiotic sensitivity testing help the veterinarian select the appropriate antibiotic.