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You get up in the dark, drive to work in the dark and drive home in the dark. Often referred to as winter depression, SAD may affect as many as 10 to 25 million Americans. According to Paul Cox, medical director of the UC Davis Medical Center Outpatient Psychiatric Clinic, the symptoms of SAD differ from the symptoms of regular depression. Cox explains that with other types of depression, patients report difficulty sleeping and a loss of appetite. They usually feel more depressed in the morning and may feel better as the day progresses.