All of them are killers - vicious destroyers of human life. But they have a good side, too. All are useful medications, used wisely. Alcohol has many curative properties and has wide applications in industry and science. Even when abused, these substances offer some relief to the abuser, however fleeting and false that relief may be.
Nicotine offers nothing to humanity whatsoever.
Nicotine addicts experience no fleeting escape from a world of worry. Most smokers smoke a cigarette because their body and mind require them too. The smoker is in the grip of what I believe is the most vicious and least rewarding addiction human beings can fall victim too. I shall not list here all the illnesses, many of them fatal, which nicotine and smoking cause. There are hundreds.