Precautions Use in pregnancy.
Some transitory redness and swelling may occur at the site of injection. A small lump, due to the slowly absorbed mineral carrier, may be felt in the subcutaneous tissues for some weeks, especially if the injection has been given too superficially. The container should be thoroughly shaken before use to ensure adequate dispersion of the mineral carrier. The recommended primary or basic course consists of three doses of 0.5 mL at intervals of 6 to 12 weeks between the first and second doses, and 6 to 12 months between the second and third doses. The vaccine should be injected intramuscularly as soon as possible after the syringe is filled.