In these persons it will aggravate the underlying cause of the constipation and cause dependence. Because the properties of this laxative herb stimulate secretions of the entire digestive system, cascara is useful in treating liver complaints, colitis, hemorrhoids due to poor bowel function, gas in the stomach, indigestion, and poor appetite. It can also stimulate flow of bile from the liver, which helps to detoxify the liver. It is also helpful in expelling parasites when used in combination with other herbs. Cascara has been used in Appalachian folk medicine to treat cancer.
Much research is needed however, before it can be used to treat leukemia.
It is generally best to take one or two capsules of cascara prior to bedtime or first thing in the morning. If intestinal cramping or diarrhea is experienced, discontinue use. It may be copied and distributed provided It is not altered in any way.