Sinai Primary Research Interests Neurotrophic factors in the mammalian nervous system. Human brain imaging. We have been studying the localization, development, and function of neurotrophic factors in the mammalian brain. We have studied EGF, TGFalpha and FGF and have focused on the EGF family of growth factors since 1982. Experimental approaches include in situ nucleic acid hybridization, immunocytochemistry, minipump infusions, neurotoxic lesions, fluorescence histochemistry, and retrograde tracing.
Present focus is on in vivo regeneration in the brain.
Our role, based in our departmental brain imaging laboratory is to design experiments and analyze MRI and PET scans to determine localization of activity and systems analysis of brain function. Department of Anatomy and Neurobiology. All Rights Reserved.