The genetic code was completed and confirmed through Khorana s chemical synthesis of polynucleotides with specified repeating sequences. The Nature of the Genetic Code Table 26-1 1. The code is highly degenerate. 1 codon 2. The arrangement of the genetic code table is nonrandom.
Most synonyms differ in their third nucleotide.
The degeneracy of the genetic code creates a built-in protection against mutation. As G and C appeared, they were incorporated into RNA and could specify additional amino acids.