Lipophilic compounds have great potential in the discovery process.
With the introduction of new automated synthesis methods, combinatorial libraries, and high-throughput screening, the capacity for screening new drug compounds has soared. However, the ability to handle this wealth of molecules could be improved. More than likely, many potential blockbusters have been lost because of inadequate formulation strategies during different stages of evaluation. In many cases, the loss could have simply been due to solubility problems. Appropriately formulated and processed nutritional emulsions stabilized by phospholipids tend to be stable for long periods.