Missing the next monthly injection by a couple of days should not disrupt the overall benefits of the treatment, but maintaining a consistent schedule is an important part of your therapy. In addition, patients missing successive doses may experience breakthrough bleeding or ovulation, with the potential for conception. Because it is possible for you to become pregnant while on Lupron Depot, it is vital that you use a nonhormonal barrier contraceptive, such as a diaphragm or condom, as a preventative measure. You may experience some mild side effects such as hot flashes, headaches, and vaginal dryness during your treatment with Lupron Depot. These side effects are similar to what happens to your body during natural menopause.
Most women stop having periods during therapy.
However, some women may experience a light period or spotting, but most will have complete absence of menstruation after the second month of therapy. Periods usually return two months after you have stopped your treatment with Lupron Depot. If they have not returned within three months, you should notify your physician. The other side effects will also disappear and your estrogen level will gradually return to normal when you have finished your course of treatment with Lupron Depot. During your treatment with Lupron Depot, it is important to keep your physician informed of any symptoms you may be experiencing.