Fluorescein Angiogram Photo Series Fluorescein Angiogram Fluorescein angiography has become a widely used technique to study retinal circulation and diseases involving the retina and choroid. Although the retina is readily available for study by direct and indirect ophthalmoscopy, fluorescein angiography is a valuable adjunt to these methods of clinical examination. Fluorescein angiography is made possible by the unique chemical and physical properties of fluorescein.
Fluorescein is an inexpensive, nontoxic, highly fluorescent compound.
It absorbs blue light and emits yellow-green light, and therefore only relatively simple modification of existing fundas cameras is necessary to perform angiography. Fundus photography in rapid sequence after intravenous injection of fluorescent dye provides information on the flow characteristics in the blood vessels, and on fine details of the retina and choroid that may not be appreciated by other means. Normal retinal vessels are impermeable to the dye. This allows a clear picture of the retinal vessels and assessment of their funtional integrity, since leakage from any retinal vessel is abnormal.