They have really revolutionized HIV disease in children in that they provoke a very profound suppression of virus load and when used adequately with good compliance they can stop the disease progress altogether and actually help restore immunity. They really have been excellent drugs. The first one to be licensed was ritonavir. For children, the ones with pediatric formulations include ritonavir and nelfinavir and Denavir only comes in capsules. Saquinavir has two forms, it s Fortovase and Invirase.
Doses vary but it also only comes in capsules.
You will use two nucleoside analog reverse transcriptase inhibitors in combination with one protease inhibitor. AZT, 3TC, nevirapine. Four drug regimens are also acceptable and they can consist also of two drugs of the class of AZT plus one drug like nevirapine and a protease inhibitor. You do whatever it takes to decrease the Of course the more drugs you give the more toxicity you have. These are the main toxicities of these drugs.