Immunochemical quantitation of clotting and fibrinolytic enzymes, and their complexes with inhibitors. Kinetics of the activation of clotting factors. Kinetics of the inhibition of clotting and fibrinolytic proteases by their natural and synthetic inhibitors. Signal transduction mediated by thrombin binding to cells. Heparin and low molecular weight heparin inhibits prothrombinase formation but not its activity in plasma.
Plasmin accelerates platelet-dependent prothrombinase assembly without activating the platelets.