But there is no glucose in the urine, so insulin isn't the problem. Osmoreceptors in the hypothalamus send a signal to stimulate ADH release. ADH stimulates water retention, which serves to dilute body fluids, ie, decrease osmolarity, so you'd expect the stimulus for ADH secretion to be an increase in osmolarity. 1200 mOsm, the concentration seen in the inner depths of the medulla, is way above what would ever normally be seen in the hypothalamus. Neutrophils are white blood cells that, like monocytes, are able to leave the blood and travel through the tissues.
Neutrophils have vesicles that contain collagenase, lactoferrin, histamine and lysosomal enzymes.
Neutrophils can express on their surface cell adhesion molecules, receptors for IgG and receptors for complement. The connective tissue outside the blood is made of a matrix which is very high in collagen and elastin. By secreting collagenase, the neutrophils can break down that collagen and make a pathway for themselves to move through the connective tissue. We discussed how the liver sequesters iron, making it less available to bacteria, which require iron to grow and reproduce. Explain how it works .