Generally done from a literature review, a meta-analysis is more a review than an analysis, properly speaking. A synthetic narcotic with a very long half-life, used in the treatment of narcotic addiction. Methadone is also sometimes used for relief of intractable pain. An amino acid under investigation as a possible neuropathy treatment. A cytotoxic anti-cancer chemotherapy, also used to treat psiorasis.
Methotrexate interferes with folate synthesis.
An approved cardiac drug that is under investigation as a possible treatment for peripheral neuropathy. The smallest amount of a substance, when diluted, which kill pathogens or stop them from reproducing. Usually means concentration required to achieve ED90. An infectious skin condition characterized by small whitish papules, generally on the face or the trunk. The boundaries will be used as a basis for stopping the trial when developed in conjunction with a sequential design, but not necessarily when used in conjunction with a fixed sample size design.