The group noted that the risk of breast cancer is increased in women using HRT and rises with increasing duration of use. The risk is reduced after discontinuation of HRT, and largely disappears after five years. The authors did note an approximate two-fold increased risk of transient ischemic attacks among women who had previously used HRT and among current users of unopposed estrogens. The Canadian Hypertension Society has released its consensus conference guidelines for the pharmacologic treatment of hypertension in pregnancy. For less severe hypertension, methyldopa is the drug of choice, with labetalol, pindolol, oxprenolol and nifedipine being second choices.
Magnesium sulfate is recommended for the prevention and treatment of seizures.