Evidence of harmful effects is based upon active ingredients. Human Health Hazards Explain the general types of hazards to humans observed with pesticides, including cancer, genotoxicity, immunotoxicity, reproductive toxicity, neurotoxicity, specific organ system toxicity. Introduce key definitions and concepts, including acute, immediate, reversible, systemic, local, and with greater emphasis on subchronic, chronic, delayed, and irreversible. Dose-Response Relationships Include general theory. Emphasize the over-reliance upon acute toxicology.
Interactions Discuss exposure to single chemicals vs exposure to several chemicals.
Exposure Explain routes of exposure, concentration, duration of exposure, and frequency of exposure. Include explanation of the nature of formulations and methods of application with an emphasis on the ability to control risks. While stressing specific chronic health effects, avoid detailed, chemical specific information. Include a definition of cancer, types of tumor, and rate of tumor formation. Discuss human cancer epidemiology the way we examine human populations and how we observe cancer.