Lu-Ann Murdoch, B.Sc. Erosive esophagitis is a chronic disorder. The 15 mg and 30 mg doses were comparable in maintaining healing and in preventing the recurrence of moderate to severe daytime and nighttime heartburn. A recent report describes three who developed osteopathy while receiving low-dose oral methotrexate for psoriasis or rheumatoid arthritis. The cumulative dose of methotrexate received by the three patients ranged from 0.67 to 3.5 g.
Drug discontinuation is necessary for resolution of symptoms.
Stretch marks in the active initial phase are pink or violet in colour without any noticeable depression of the surface. Drug and surgical therapy for stretch marks have been unsatisfactory. Topical tretinoin has produced variable results in clinical studies of patients with permanent stretch marks. The authors suggest that to be effective, therapy for stretch marks must be started during the active stage, before permanent scarring has occurred. This is believed to be the result of many purported benefits, even though the efficacy of these supplements is not yet proven.