Acute lesions occur at the edge of the chronic lesion. Choroidal neovascularization may occur in these patients. Vein Occlusions Central retinal vein occlusion is a common retinal vascular abnormality usually seen in patients over 50 years of age. A thrombosis of the central retinal vein in the area of the lamina cribrosa is commonly seen on histopathologic examination. An ischemic retinal vein occlusion may progress to capillary nonperfusion, retinal neovascularization, and vitreous hemorrhage.
Neovascular glaucoma is a dreaded complication of an ischemic vein occlusion.
Nonischemic vein occlusions have a better prognosis. Macular edema may also occur in eyes with venous occlusions. The condition usually resolves within several weeks with a good prognosis. Early in the study, the lesions are hypofluorescent. Later in the study, they become hyperfluorescent.