Clinical work Research is closely integrated with clinical work at the neurosurgical clinic of the Karolinska Hospital. The clinic has 60 beds including 11 beds at the neurointensive care unit. There are about 3300 admissions a year and the yearly number of operations is about 2600. About 300 of the operations are performed with the Gamma Knife. In addition, there is a foreign patient unit closely related to the neurosurgical clinic.
P prevents occurrence of spasm.
The effect of the non-peptidergic substance P antagonists, Nk1, NK2 and NK3 in animals with an experimental SAH on CBF and metabolism is under investigation. Moreover, the relationship between CBF and metabolism during the acute phase following an SAH is studied. Electric spinal cord stimulation, SCS, is a widely used therapeutic procedure in pain states resistent to conventional therapy. The mechanism underlying the effect of SCS is unknown. The project is exploring the mechanisms both regarding the beneficial effects on microcirculation and on neuropathic pain.