A first novel, however, must begin on page one. The purpose of page one is to convince the reader to read page two, and so on, and so on. You've got to build a reputation beginning in the very first sentence of your first published novel. If you seriously want to be published, thoroughly research the marketplace and determine what publishers want to buy. When you produce what a publisher wants, you'll be accepted.
Publishers cease to exist if they stop buying manuscripts.
And don't try to write like a best-selling author. Be sure to mention the title.