Other physical effects. Permanent hearing loss, especially from inhaling toluene found in paint sprays, glues and dewaxers, is a big risk for inhalant users. Irreversible damage to nerves throughout the body, a condition called polyneuropathy, is common. Among the most vulnerable nerves are those in the back and legs. Inhalants chemically attach to fatty tissues, especially the white myelin sheaths that protectively coat nerve axons, somewhat like the insulation on electrical wires, and speed nerve conduction.
Inhalants damage the myelin and destroy it.
Some of these changes are temporary, but others can produce long-lasting damage. They also sometimes interfere with blood cell production, which can result in the life-threatening condition known as aplastic anemia. Inhalants also can interfere with the normal heart rhythm and lead to cardiac arrest. Toluene Toluene is a colorless liquid with a sweet, strong odor. It is used as a solvent and in aviation gasoline, making other chemicals, perfumes, medicines, dyes, explosives, and detergents.