Hydrocephalus occurs with low incidence. Since the beige mutation causes specific types of immunodeficiencies, it is not surprising that these mice are more susceptible to infectious diseases. This mutation is a homologue of the rare human disease Chediak-Higashi syndrome. Teaching sets of glass microscope slides are also available. These can be obtained from the Pathology Program at The Jackson Laboratory.
Osteoclasts derive from hematopoietic stem cells according to marker, giant lysosomes of beige mice.
Lesions in Brangus cattle with Chediak-Higashi syndrome. Adaptive immune defects and delayed rejection of allogeneic tumor cells in beige mice. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, pp 195-206, 1990. Galli SJ, Hammel I. Unequivocal delayed hypersensitivity in mast cell-deficient and beige mice. Granulocyte function in the Chediak-Higashi syndrome of mice.