PolyGalactoseGOLD TM consists of a 20 nm gold colloid coated with multiple galactose epitopes. This reagent is taken up by hepatocytes through the ASGP-R and can be used for a variety of applications including quantifying receptor activity and distribution. In combination, these kits provide great experimental design flexibility. The samples are then sent to BioPAL for neutron activation and analysis.
Researchers can expect assay results within ten working days.
The ability to re-assay stored samples is a major advantage for pharmaceutical development. Currently, PolyGalactoseGOLD TM is only available as a gold colloid. However, BioPAL is actively developing new isotopic markers that will allow researchers to make multiple measurements in ASGP-R activity as a function of time, disease, or intervention within a single in vivo study.