The caretaker's job can be exhausting. Common AD changes in behavior include agitation, disrupted sleep, delusions, aggression, depression and wandering. Caregivers are advised to reduce household clutter, create a calming environment, encourage a regular schedule, and to use very specific, brief repetitive directions when making requests. Adult day-care centers provide needed respite for the caregiver and appropriate care and management for AD patients. There is no firm evidence that AD can be prevented by lifestyle measures, yet prevention advice proliferates for seniors.
Physical exercise is also important, to keep oxygen flowing to the brain.
Researchers are optimistic. A month rarely goes by now without the discovery of a new gene, protein or chemical process that contributes to the understanding of the disease. Scientists are testing other new drugs for AD at many large teaching hospitals and universities. The possible benefits of vitamin E and ginkgo biloba are also under investigation. Early diagnosis techniques have become much more accurate and make it possible to begin interventions earlier, and doctors today are better informed about aging.