I admit I have a prejudice. But while that may guide me in finding lunch, I check my prejudices at the door when I arrive to manage my department. You would be hard pressed to find anyone to disagree with the idea that workplace discrimination should be avoided at all costs. Failing to provide fair treatment can lead to poor morale, negative press, legal penalties, and financial ruin. Essentially, provide equal treatment to everyone.
Employers can usually reward employees for their experience, expertise, and loyalty to the firm.
However, a manager can't reward one employee because she's better at climbing stairs and penalize another because he uses a wheelchair. Obviously, no employer would set out to do that, but it has happened, and that's why EEO laws were put on the books. Make sure you are equal and unbiased in your dealings with employees. Remove bias in your hiring, firing, and promotion practices. Eliminate illegal screening processes in order to provide every opportunity for individuals to seek employment with your firm.