This common, spiral-shaped bacterium can weaken the protective mucus coating of the duodenum, allowing acid and bacteria to ulcerate the sensitive lining underneath. About two-thirds of the world's population is infected with H. pylori, but most of those infected do not exhibit symptoms related to the infection. Although rare, ulcers are sometimes caused by stomach or pancreatic cancer. Duodenal ulcers are not caused by spicy foods or stress .
Duodenal ulcers occur more frequently in men than in women.
Duodenal ulcers are also associated with cigarette smoking . Check with your health-care provider about alternatives to these medications. Smokers with a history of duodenal ulcer should quit smoking. May wake the person at night. May be relieved by antacids or milk.