In such a case, the man's female hormone level may be inordinately high, resulting in a low sex drive and reduced sexual performance. Marijuana Research suggests that long-term use of marijuana lowers the sperm count, interferes with sperm motility, and causes sperm to develop abnormally. In addition, some findings suggest that marihuana may reduce blood testosterone levels. Marijuana use, like alcohol use, has been associated with the development of gynecomastia. These effects may be temporary, but also may lead to permanent infertility.
Many prescription medicines can harm sperm or otherwise impair sperm production or quality.
Therefore, men who are trying to conceive a child with their partners should check with their doctors before using any prescription drugs. Although chemotherapeutic agents are constantly being improved and can successfully treat a wide variety of cancers, such agents pose many fertility concerns. Chemotherapeutic drugs often exert prolonged, toxic effects upon gonadal function. In addition, hormonal function of the testes may be impaired. Germ cell toxicity is especially noticeable following treatment with chemotherapeutic drugs known as alkylating agents.