This is one of the explanations of the paradox of oxidant ozone serving as antioxidant therapy. By improving tissue oxygenation, ozone diminishes oxidosis. Ozone tightens arteries. Ozone opens up arteries. That makes ozone a vasoconstrictor.
Ozone commonly creates a flush effect if given rapidly.
That indicates opening up of blood vessels, and not tightening them up. That makes ozone a vasodilator. Many of my patients report a desirable sense of warmth in their tissues after ozone therapy. This is another explanation of the paradox of oxidant ozone serving as antioxidant therapy. By improving tissue blood supply, ozone counters anoxia and oxidosis.