Make plans to be with someone. If worse comes to worst, at least use the phone to make contact with others. Again, remember others are lonely on holidays when they can't be with their families. If you can't find ways to relieve the depression, don't hesitate to seek professional help. If possible, try to find someone that has some understanding of the special needs of the physically ill patient.
Nobody wants to be in the hospital for a holiday.
However, if it's necessary, make the most out of a distressing situation. Decorate your room. Have your family help. Arrange for your family to visit and perhaps share a holiday meal with you. If you're on I.V.'s and can't eat, use your imaginations and sense of humor and pretend it's your turkey dinner.