Results are most accurate with failure of early regimens. These are compared in Table 2-3. Interpretation requires knowledge of mutational changes, eg, expertise. Technician experience influences results. Assesses total effect, including mutations, mutational interactions.
Reproducibility is good.
Assays vary considerably based on cost, the number of mutations tested, and simplicity and accuracy of reporting. The table indicates the amino acids and corresponding letter codes used to describe mutations in genotype analyses. The 75 mutation is rarely seen in vitro . Instead, mutations listed for AZT should probably be viewed as primary and secondary d4T mutations, as well. Occurs with or without TAMs.