The effects and stages vary depending on the drug.
Prolonged use can cause coughing, wheezing, and lung infections the same as cigarettes.
Cocaine makes the heart beat faster and increases the risk of heart failure. It also leads to physical exhaustion, poor concentration, malnutrition, and sexual dysfunction. It also increases heart rate and blood pressure, as well as causes confusion, severe depression, memory loss, and exhaustion. It also increases energy and sensual feelings, but often these are followed by headache, fever, nausea, and vomiting. Combining it with alcohol can be fatal.