High power view of some of the spindle cells. One of many atypical mitotic figures is seen. Medium power view from the area bounded by the ink dots. High power view of above. The orange area in the cytoplasm of the cell that is near the center of the picture may represent keratin.
Intercellular bridges are barely visible above and to the left of the orange area.
Another high power view from an area where most of the cells have epithelial characteristics. Some have vacuolated or foamy cytoplasm resembling histiocytes. Abnormal mitoses are seen. There were areas where plump spindle cells merged morphologically with cells having epithelial characteristics. Click on IPOX for the immunoperoxidase studies on this case.