Researchers have found a selective absence of Glu R-2 in the ALS motor neuron population. The BIO 14.6 hamster is a model for autosomal recessive hypertrophic cardiomyopathy. These animals die from progressive myocardial necrosis and heart failure. The latter regions are homologous to human chromosome 2p13. Two prenatal methods for diagnosing CMD have been developed.
Mitochondria contain their own DNA, and a single cell can have hundreds of individual mitochondria.
Some have normal DNA, while some have mitochondria with defective DNA as a result of mutation. MH is a fulminant muscle rigidity following inhalation of some types of anesthetics or injection of depolarizing muscle relaxants during the course of surgery. Elevated core temperature, muscle breakdown, and acidosis also occur. It is one of the leading causes of death with anesthetics, usually due to heart dysrhythmia. Mutations located in a different part of the same gene have also been linked to hypokalemic periodic paralysis.