This is not a complete read-through. Skip straight to the pages their advice applies to. Perfect your first three chapters. You're going to send these out while you finish polishing up your manuscript. You'll be amazed at everything you didn't catch on the screen.
Many writers also like to read aloud.
I do both. The final read. On the computer, read the second to the last chapter first, and proceed backward to chapter one. After chapter one, read your final chapter. Reading this way you'll be amazed at how obvious the characters' growth is.