By inhibiting platelet adhesion and activitation, myointimal proliferation is reduced. Inhibition of platelet aggregation mediated by thromboxane may also be a factor in reducing the amount of thrombosis. Corticosteroids have been used to treat eosinophilic pneumonitis, pulmonary infiltrates and pulmonary granulomas before and after adulticide therapy. Ivermectin is not approved for use as a microfilaricide but it is the most effective and practical agent. The dog should be observed in the hospital for the day and then discharged.
Reactions can begin within hours and signs include vomiting, diarrhea and lethargy.
Severe reactions can be life-threatening and include tachycardia, tachypnea, weakness, pale mucous membranes and hypotension. Treatment includes rapid-acting corticosteroids and IV crystalloid fluid administration. Prevention Environmental Control Avoid mosquito infested areas, and high mosquito times such as early morning and evening. Protection of dog's quarters from mosquitoes, staying indoors - indoor dogs usually show much lower incidence of infection. Insect repellents - most are safe if not applied too heavily, but must be applied frequently and consistently to be effective.