In a study published in the September issue of the journal Clinical Pharmacology Therapeutics, researchers in India report similar findings with the anticonvulsant drug carbamazepine. Patients who took the drug with grapefruit juice had ''significantly increased'' concentrations in their blood, the researchers write. Similarly, older patients prescribed felodipine should avoid taking the drug with grapefruit juice, according to a study presented this week at the annual meeting of the American College of Clinical Pharmacology. Elderly patients who took the medication with grapefruit juice had blood levels of the drug that were 3.5 times higher than normal, Dr. George Dresser of the University of Western Ontario in Canada, reported. These levels can cause a more marked drop in blood pressure, which may be dangerous, Dresser said.
Nutrient increases are desirable, however, when it comes to prescription drugs, be very careful.
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