It has thus a role in the homeostasis of the intraganglionic compartment. The ganglia are richly vascularized particularly where the nerve cell bodies are located. Unlike the blood vessels in the central nervous system the ganglionic vessels are permeable to dyes and serum proteins, like albumin and globulins, i.e. ganglia are located outside the blood-brain barrier. Fenestrations are present in the endothelial cells through which diffusion of substances can take place. The presence of macrophages in the ganglia is most like of great importance in such conditions since they pick up and try to degradate abnormal substances which have passed into ganglia from the circulation.
Injuries develop only when the protective capacity of the macrophages has been exceeded.
Acta Univ Upsaliensis.