Eosinophilia sometimes is present. Abdominal ultrasound may be better than barium enema to diagnose intussusception, since HSP-related intussusception more often is ileoileal instead of ileocolic as is typical in idiopathic intussusception. Doppler or radionuclide testicular scan shows normal or increased blood flow in HSP, in contrast to the decreased blood flow seen in testicular torsion. Consultation is recommended for patients with renal involvement prior to discharge from the ED and for all patients who appear acutely ill. Clinicians often use corticosteroids to treat abdominal pain, subcutaneous edema, and nephritis, but no prospective, placebo-controlled studies have demonstrated their effectiveness.
Most patients recover quickly without treatment.
Treatment in patients with severe HSP nephritis includes many different modalities, but again, no prospective controlled studies prove the efficacy of any of these treatments. Other options include flurbiprofen, ketoprofen, and naproxen. Inhibits inflammatory reactions and pain, probably by decreasing activity of enzyme cyclooxygenase, which results in inhibition of prostaglandin synthesis. Inhibits inflammatory reactions and pain by decreasing activity of enzyme cyclooxygenase, which results in decrease of prostaglandin synthesis. In addition, they modify the body's immune response to diverse stimuli.