Follow all instructions on the label. It is labeled for use on range, permanent pasture, fallow cropland, non-crop areas, and Conservation Reserve Program acreage. Apply at bud to bloom stage or in the fall. Follow all label instructions and precautions. Always read the label before buying and again before applying any pesticide.
Russian knapweed is successful because it out competes most other broadleaf plants and many grasses.
It is often found in a dense, single species patch because it releases a chemical into the soil that prevents other species from germinating. An important part of any control program is to get rid of this chemical by tilling the soil. Following tillage, seeding with a competitive grass seed is recommended. Grasses are better than clovers or alfalfa because a broadleaf herbicide can be sprayed if the knapweed reappears. CSU recommends smooth brome, streambank wheatgrass, thickspike wheatgrass, crested wheatgrass, and Russian wildrye.