Does not cause paralysis of the worms. Administration over 3 days lessens the risk of worm bolus formation. Pregnancy C - Safety for use during pregnancy has not been established. Because this agent causes flaccid paralysis, less likelihood exists of worm bolus formation and development of complete obstruction. Causes flaccid paralysis of the helminth by blocking response of ascaris muscle to acetylcholine.
Main advantage is ability to administer as a single dose.
Poorly absorbed from the GI tract and partially metabolized in the liver. Systemic Antihelminthic Agents - Alternative therapy for ascaris infection. Broad-spectrum antihelminthic agent which is effective against ascaris as well as hookworm, tapeworm, liver fluke and pinworms. Contraindications Hypersensitivity to albendazole. Interactions Carbamazepine may accelerate albendazole metabolism.