ARD usually appears during the third week in training. Characteristic symptoms include fever, malaise, sore throat, hoarseness and cough. The contribution, if any, of adenoviruses to the pertussis syndrome is not known. Infections of the Eye - Acute follicular conjunctivitis, which is part of the syndrome of pharyngoconjunctival fever, can also occur as a separate entity. The disease is also associated with swimming pools.
Epidemic keratoconjunctivitis is a distinctly different syndrome.
This syndrome is characterized by an aggressive conjunctivitis, pain, photophobia and lymphadenopathy followed by the development of superficial punctate keratitis, corneal opacities may last for several years. Adenovirus keratoconjunctivitis mainly affects males in Western countries or children in Asia and may last for 4 to 6 weeks. Antibody to Ad 8 is uncommon in American school children, whereas approximately half of the Japanese or Taiwanese children have such antibodies. This syndrome occurs predominantly in 6 to 15 year old boys. The syndrome consists of acute dysuria with haematuria and is mainly associated with Ad 11.