Here we should make difference between short acute fatigue and long-term chronic fatigue. The differentiation is not only based on the duration of the fatigue. Opposed to short acute fatigue long-term fatigue is often not related to the degree of exertion. Some people with MD have problems with sleeping which is inconvenient in the daytime. Depressions often occur with people suffering from a chronic disease and they mostly cause fatigue.
Research shows that long - term exposure to stress leads to exhaustion.
Suffering from a chronic disease and its consequences for the daily life cause much stress. Besides the original causes, a variety of causes maintain or even intensify the level of fatigue. This complexes the matter even more. On the one-side stands the way a person deals with fatigue on the other hand stands his attitude towards fatigue. The normal reaction to physical fatigue is rest.