Focuses on fundamental concepts in cell biology at the advanced level. Provides students with an understanding of current problems in cell biology, and its scope is meant to serve as the basis for more specialized course work. Lecture topics will be developed around the primary research literature and supplemented with textbook readings. Lamppa, Kron, Dubreuil. Examines the molecular basis of the structure, function, dynamics and biogenesis of the formed elements of the cytoplasm.
Featured structures are the membranes, organelles, and filamentous assemblies of eukaryotic cells.
Schwartz, Astumian, Dawson. Chromatin structure and its role in transcription, communication between nucleus and cytoplasm, translation, protein folding and assembly, molecular chaperones, elements of signal transduction, homeostasis, growth control and the cell cycle, cytoarchitecture, cell adhesion and migration. A graduate level course, open also for advanced undergraduate students, on classical and molecular genetics. The course will provide an overview of genetic analysis and genetic mechanisms in one quarter. Coverage of the fundamental tools of genetic analysis as used to study biological phenomena.