Rat breast cancer models have also proven useful in understanding the role of dietary factors in breast cancer causation. Mouse cancer models are also used in preclinical testing of new drugs and combinations of drugs. Within the past ten years or so, animal research in breast cancer has expanded to include the growth of human breast cancers and, even more recently, human precancerous breast lesions, in mice with no immune systems. These xenograft models mirror the pathological, biological, and clinical pictures of human breast cancer and allow for experimentation which is not possible in women. Such models are being used to test new methods of treatment and prevention, as well as to identify genetic and environmental factors that influence breast cancer development and growth.
Research continues to lead to improved treatments and longer disease free survival.
We hope that likeminded citizens will join us in working for rational public policy that assures the continued appropriate use of animals in the course of good science.