However, the safety of blood transfusions is equal to or even greater than the safety of many common medications and medical procedures. Blood is safe enough and it will get even safer. Since the drug's approval, the FDA has received seven reports of severe complications in women taking this drug. Of these patients six required hospitalization and one required surgery. During this same period, an additional eight patients taking the Lotronex were stricken with ischemic colitis.
Ischemic colitis is a serious condition in which blood supply to the colon is compromised.
The colon may become damaged by severe inflammation and ulceration of the lining of the intestine. Ischemic colitis may require hospitalization and possibly surgery. These reports prompted the FDA to add important safety information to the labeling and patient inserts for Lotronex. This information highlights the risk of serious complications and emphasizes what patients should do if symptoms of such problems arise. If you are considering this medication or currently take Lotronex, here is what you should know.