The cultural life and history are all documented in the recently opened Regional History museum in Prienai. The people of Prienai region are very sports orientated with a sports school providing extracurricular activities for active students after school. Prienai has the local basketball team and the local airport has a flying club and flying competitions throughout the summer months. Self-defense, aerobics and orientation competitions are also popular. As of 1 January 1998 the region had 842 active enterprises.
Private capital is the main financial source opening most enterprises.
Sewing, wood or timber processing, construction and a variety of service organizations form the main branches of the local economy. The clothing and wood industries are the largest exporters in the region. The timber processing companies include AB Rudupis , AB Prienu melioracija , AB Maciunai , AB Ziobas , UAB Doleta . The Prienai forestry department has the responsibility of tree planting, maintenance and forest planting. Currently, the largest and unique companies in the district include, in Pociunai, AB Sports Aviation factory, designing and building gliders.