Bone marrow aspirate and biopsy were performed with minimal discomfort to the patient without complications. Samples were sent for histology, cytogenetics, immunocytometry and PCR analysis. WBC 3.7, hemoglobin 8.9, hematocrit 27.3. BUN 22, creatinine 1. LDH mildly elevated at 896.
Liver function tests otherwise within normal limits.
Bone marrow biopsy revealed a variably cellular overall moderately hypercellular marrow. Immunoperoxidase studies revealed the aggregates are comprised of a mixture of B and T lymphocytes, plasma cells, histiocytes and fibrous cells. Myeloid cells were moderately proportionately decreased. Megakaryocytes are mildly to moderately decreased. Immunophenotype of disaggregated marrow cells showed no evidence of a B Cell proliferative disorder.