Financial support is available for suitable candidates. Moleculargenetic and phenotypic studies of knockout-mice showing dwarfism On creation of transgenic animals, a mutant mouse line was produced by random integration of the gene construct into the host genome. Homozygous knock-out animals from this line show reduced body growth and tooth abnormalities. Subsequently, further molecular genetic and phenotypic investigations of the knock-out mice will be carried out. The period specified for elaboration will be two years.
Financial support is available for suitable candidates.
Examination of contrasting obesity phenotypes in leptin receptor defective mice We have previously described contrasting obesity phenotypes in leptin receptor defective mice. The period specified for elaboration will be two years. Financial support is available for suitable candidates. Reproduction biotechnology including hormonal treatment, AI, embryo collection and transfer are the components of an interesting experimental work. Experiance in handling of laboratory animals such as rabbits are adventageous but not an obligate prerequisite.