Progestogens can be either natural or synthetic.
Progestogens have been used for years in infertility treatment and to replace the natural progesterone in women with premature ovarian failure. Progestogens are used to treat abnormal uterine bleeding and for contraception in birth control pills and in Depo-Provera . There are two controversial topics you may have heard of. First is the use of natural versus synthetic Progestogens in hormone replacement therapy. HRT consists of the hormone estrogen and, if your uterus has not been removed, progesterone.