We have also added a section on techniques in protein chemistry including purification methods, sequence determination and methods of determining their structures. This includes modern aspects of mass spectrometry and the uses of protein databases. We also include a section on the biochemistry of diabetes. Gene transcription and its control have been totally revised with separate chapters for prokaryotic and eukaryotic gene transcription and control, the latter obviously greatly changed and expanded. Ribozymes now are included as a major addition.
Protein synthesis includes the mechanisms of chaperone and chaperonin actions.
Cell signalling has been totally rewritten and is one of the book s largest chapters. This is followed by a new chapter on cell cycle control and the molecular biology of cancer. Muscle contraction has been updated with the swinging lever mechanism. There have of course been many short alterations to update material or make things clearer. It is well organised, beautifully illustrated and designed, a pleasure to read and a delight to study.