Other viruses in this group include hepatitis A and poliovirus. Coxsackievirus is transmitted via fecal contamination. Mosquitoes also can transmit coxsackievirus and other enteroviruses. They feed on birds or other animals infected with the virus and then bite humans. Mosquito control is one method of controlling outbreaks.
Outbreaks often peak in summer and fall when humans, animals and insects interact the most.
Children are more likely to be infected with coxsackievirus because of their increased exposure opportunities and age-related lack of antibodies to the virus. No treatment exists for coxsackievirus. Antibiotics are ineffective in treating viral infections. The virus simply must run its course. Researchers currently are testing antiviral drugs that may someday treat more severe cases of the infection.