Researchers believe it inhibits the action of enzymes that cause cartilage breakdown. The supplements are synthetic versions of the natural substances. The benefits of glucosamine and chondroitin supplements haven t been scientifically proven. Several small studies suggest glucosamine and chondroitin may help reduce joint pain in patients with osteoarthritis. Other studies have found no positive effects.
Researchers are more concerned about the long-term safety of glucosamine and chondroitin.
The National Institutes of Health is getting on the bandwagon with a study of its own. Patients will receive monthly evaluations of pain and function. In the meantime, doctors say osteoarthritis patients shouldn t stop taking their physician-recommended medications. Patients who are taking any type of dietary supplement should tell their physician to prevent drug interactions. The information on this factsheet is not meant to substitute for a consultation with your physician or with another healthcare professional.