The strategy for using memory maker is to add all the stuff you want in autoexec.bat and in dosstart.bat together in one autoexec.bat file. After your done move the items you want in Dosstart.bat back including the addresses. Leave all the addresses for the remaining items. Most of the time all you need is the CD-ROM driver. Don't load smartdrv.
Most games run fine without.
It is a benefit for everything using disk access a lot. You may not need to load the mouse.