Contributed by Kathleen Philippi, R.N., BSN Cystic fibrosis is a disease of the exocrine glands, affecting multiple organ systems in varying degrees of severity. The glands secrete an abnormally thick mucous that blocks the glands and other areas. The lungs and pancreas are two important organs that are affected. The most devastating part of the disease is related to the blockage of the breathing tubes of the lungs. This causes chronic bronchitis and pneumonia .
Frequency is equal in both sexes.
It is possible to detect the abnormal gene in about 75 percent of those who have it. However, if these tests are done, it is very important for someone experienced in genetic counseling to help a couple make informed decisions about pregnancy. The clinical effects of cystic fibrosis may become apparent soon after birth or may take years to develop. They include major deviations in sweat gland, respiratory, and gastrointestinal functions. Sweat gland dysfunction is the most consistent abnormality.