Phenytoin is a highly effective and widely prescribed anticonvulsant agent.
Phenytoin is however, associated with both dose related side effects and hypersensitivity reactions. Phenytoin is associated with both dose-related side effects and hypersensitivity reactions. A small percentage of patients will experience a distinctive reaction referred to as the phenytoin hypersensitivity syndrome. This syndrome can have a variable spectrum of clinical and laboratory findings. We report a patient with the phenytoin hypersensitivity syndrome who developed multi-system organ failure.