Hepatic adenomas are usually solitary lesions. Review of case reports6,19 reveals that a substantial percentage of cases involve more than one lesion. An exact definition with specific criteria for hepatic adenomatosis has not been established, since few well-documented cases have been reported. Other distinguishing features of hepatic adenomatosis are that it occurs equally in men and women and it is not associated with malignant transformation or with the use of oral contraceptives. Our case is unusual in several aspects.
Hepatic adenomas are usually solitary and are associated with a history of oral contraceptive use.
While the finding of more than one adenoma is not uncommon, such lesions may not be resectable when discovered. Furthermore, successful hepatic resection during pregnancy is rare. Our case emphasizes that hepatic adenomas may occur without the use of oral contraceptives and that resection of such lesions should be considered because of the risk of hemorrhage and the associated possibility of malignancy. Furthermore, it seems prudent to avoid subsequent pregnancies and oral contraceptive use in this setting. Liver cell adenomas associated with use of oral contraceptives.