Swelling results when protein is lost from the blood stream. Urine discoloration results from blood in the urine . This occurs because of loss of blood within the damaged glomeruli. The disorder is uncommon, affecting 4 out of 100,000 persons. It affects both sexes and is evenly distributed across age groups.
Generalized edema is often present.
There may be signs of acute renal failure in addition to the above symptoms. Urinalysis may show protein , renal tubular cells, blood, white blood cells, and casts . Protein, urine test may be positive. The creatinine clearance may be decreased. A potassium test may be elevated.