Laboratory workers preparing primary cell cultures from African green monkeys resulted in an outbreak of a previously unrecognised disease. Since 1995, there have been repeated outbreaks Current Ebola News The Hot Zone by Richard Preston. The dramatic and chilling story of an Ebola virus outbreak in a surburban Washington, D.C. laboratory, with descriptions of frightening historical epidemics of rare and lethal viruses. More hair-raising than anything Hollywood could think of, because it's all true. Based on research and interviews with experts in virology, molecular biology, disease ecology, and medicine, an exploration of our battles with microbes examines the current outbreak of infectious diseases and outlines what can be done to prevent the coming plague.
Filoviruses are a major category of emerging viruses .
Particles are rounded at one end with a distended swelling at the other. The core has a striated appearance similar to that of Rhabdoviruses . In addition to in vivo effects, sGP also increases virus yield and decreases cytopahtic effects of the virus grown in cultured cells. The clinical manifestations of Ebola virus infection are severe. By day twelve the skin starts to peel away from the rash.