Raphel paints The Transfiguration. Luther posts his 95 Theses in Wittenberg. Hernan Cortes conquers the Aztecs. Diet of Worms. Luther refuses to back down.
Imperial troops sack Rome.
The Turks besiege Vienna. Henry VIII of England breaks with Roman Catholic Church. Jacques Cartier sails up the St. Lawrence River. Hernando de Soto discovers the Mississippi River. Aims to reform Catholic Church.