Once the animal is in the trap it must usually be immobilized for further procedures. Pole-syringes are usually ineffective, as the trapped animal will avoid the pole, will pull at and bite the pole, or will pull away from the pole before the injection can be completed. If the trap has a moveable panel, use it to push the animal against the side of the trap while the drug is administered using a hand-held syringe. If there is no moveable panel, use sticks for the same purpose. The dart is likely to be pulled out and bitten, but usually only after injection has been achieved.
Oral medications are difficult to administer to a specific individual unless in a captive situation.
Free-living primates captured in this way will usually be those that are willing to take food from people. This technique may therefore be useful for selectively capturing and removing problem animals. Pre-baiting is usually essential to familiarize the animals to the food and to the capture site. This also allows some prediction as to when the animals will receive the drug. Use a variety of known feed items from the area, or try a home-made bait.