Experienced CF clinicians can often provide adequate support with mask ventilation to minimize the need for tracheal ventilation. The masks, however, may be uncomfortable or cause claustrophobia. Ventilatory pressures are limited by the design of mask ventilators and by air leaks around the mask and through the mouth. The level of inspired oxygen is variable and difficult to control. Mechanical ventilation simulates normal breathing and is not inherently painful, but masks and tracheal tubes can cause local discomfort.
Patients receiving assisted ventilation often require intensive care.
The associated intravenous catheters and other limitations on daily activities can significantly reduce one s quality of life. Sedatives that are commonly used in such settings can impair judgment and the ability to make essential decisions. Like all treatments, the associated costs and risks must be considered in light of the potential benefits. CF complications that are quickly reversible usually merit vigorous treatment, including assisted ventilation when needed. Assisted ventilation may be appropriate for some individuals with irreversible complications, to provide time for final affairs.