Category Third Generation Cephalosporin Pharmacokinetics Ceftriazone is a long acting third generation cephalosporin, with half life of 8 hours. It has a good CSF penetration and eliminated equally in urine and bile. Contra Indications Ceftriazone is contraindicated in patients with hypersensitivity to cephalosporins. Precautions Hypoprothrombinemia and bleeding are specific adverse effects of cephalosporins.
Precautions are to be taken in renal failure.
Interactions Ceftriazone gives Disulfiram like reaction with alcohol. All rights reserved.