The condition is characterized by prolonged bleeding, especially into soft tissues and muscles. Of particular importance is the high risk of intracranial bleeding. This condition can be caused by liver or kidney diseases. P is a blood product made from pooled human plasma. In addition to Factor XIII, it contains human albumin and glucose.
P is made from human blood.
Therefore the presence of infectious agents, including unknown diseases, cannot be excluded. However, studies have shown that HIV is not transmitted in this product. Their plasma is not used if any screening test is positive. The product is subjected to 10 hours of 60 C vapour heat under pressure. At present, there is no test to screen out CJD-associated donations, nor do current viral inactivation methods eliminate the abnormal prion protein.