We see such cases in the South and Southwest, and long the Mississippi Valley. Periodicity is the symptom upon which Quinine is given. China has periodicity, but in no greater degree than many other remedies and is not so frequently indicated as routine prescribers suppose. Allopaths give Quinine whenever there is any periodicity in complaints. Still periodicity is a strong feature in this remedy.
Pains come on with regularity at a given time each day.
Intermittent fevers appear with regularity and run a regular course. A part of this periodicity is an aggravation at night, and sometimes sharply at midnight. In colic that comes on regularly every night at 12 o'clock, and it may be, perhaps, a week before you, suspect it to be a China colic. A lady had colic and bloating of the abdomen every night at 12 o'clock. After suffering many nights a single dose of China , prevented any further trouble.