Joint inflammation caused by deposition of uric acid. Crystals in the joints, causing pain, redness, warmth and swelling and most commonly affecting the big toe. May involve any large or small joint. Causes A high level of uric acid in the blood due to increased production of uric acid or decreased elimination of uric acid by the kidneys.
Involved joints are red, hot, swollen, and very tender.
Skin over the joint is red and shiny. Some blood diseases, such as polycythemia and leukemia. Family history of gout. Men over 60. Many disorders including thyroid problem, kidney disease, anemia, hyperlipidemia, high blood pressure, diabetes, and vascular disease.