To make a start at coordinating development of the dictionary, an informal breakfast meeting of interested parties was arranged on May 11,1999, at the annual NIH-sponsored workshop on zebrafish genomic and genetic tools. Collaborating with Jonathan Bard and Fons Verbeek to develop a dictionary and, ultimately, a detailed anatomical atlas for zebrafish. Characterize large in situ dataset ranging from 0-48 hour embryos. Characterize in situs generated from a normalized cDNA library derived from tailbud to 10 somite stage embryos. Focus is on expression in 0-24hr embryos.
Interest is in vessel development.
Has developed sophisticated 3-D reconstructions from confocal image that will need to be annotated to denote distinct structures. Jonathan was the driving force behind the development of the mouse anatomical dictionary. He has recently begun doing the same for the zebrafish. A draft of a zebrafish atlas Jonathan has developed was circulated at the meeting. When fully annotated, it is expected that this effort will eventually yield a definitive 3-D atlas for the zebrafish.