Test code links throughout this Guide refer to the corresponding test in the User's Guide. Leukocytes migrating toward the chemoattractant demonstrate stimulated, unidirec- tional movement through the filter resulting in a larger number of cells in the lower filter layers. The number of cells that have migrated through are counted and a chemotactic index is then calculated. In the absence of a chemoattractant, leukocytes move only in a random, multi-directional manner. In the presence of a chemoattractant, leukocytes move in a unidirectional manner in response to the concentration gradient of that attractant.
Normals are dependent on the control sample drawn for comparison at same time.
Coates TD, et al. Laboratory evaluation of neutropenia and neutrophil dysfunction. In Manual of clinical immunology , 4th ed. NR Rose, et al, eds. Hill HR, et al.