2.Giving estrogen with a short-acting corticosteroid does not decrease the incidence of retained fetal membranes. Estrogen is luteolytic and, therefore, requires an intact endometrium to be effective. 3.A long-acting corticosteroid does increase the incidence of premature separation of the placental membranes and uterine inertia. This method does have a high calf mortality rate. It is used primarily on cows that are valued more for their milk production than genetic offspring.
Prostaglandin is luteolytic.
It does require a functional CL3 to initiate another cycle. The mechanism of action should prevent implantation of any fertilized ova. This hormone delays passage of the embryo through the oviduct. Estrogen available in an oil vehicle has the side effects of prolonging the length of estrus and stimulating secretions. An intrauterine douche may be used 4-8 days post breeding.