Toxicity Perchloric acid is a highly corrosive substance that causes severe burns on contact with the eyes, skin, and mucous membranes. The acute toxicity of perchloric acid is moderate. This substance is a severe irritant to the eyes, mucous membranes, and upper respiratory tract.
Perchlorates are irritants to the body wherever they contact it.
Perchloric acid has not been shown to be carcinogenic or to show reproductive or developmental toxicity in humans. Flammability and Explosibility Perchloric acid is noncombustible. It is unstable and can decompose explosively at ordinary temperatures or in contact with many organic compounds. Mixtures of perchlorates with many oxidizable substances are explosive. Temperature increases the oxidizing power of perchloric acid, and hot concentrated solutions are very dangerous.