Isolated plasmacytoma of bone Only a single plasma cell tumor is found in the bone without any other evidence of cancer. Patients may develop multiple myeloma at a later time. Extramedullary plasmacytoma Plasma cell tumors are found only outside the bone and the bone marrow in the soft tissues, usually the tonsils or tissues around the nose. Patients may develop multiple myeloma at a later time. Macroglobulinemia Plasma cells that produce a certain type of M-protein are found in the blood.
Patients usually have swollen lymph nodes and spleen or liver.
Monoclonal gammopathy of undetermined significance M-protein is found in the blood without symptoms or other signs of cancer. The plasma cells do not decrease even though treatment is given. How plasma cell neoplasms are treated There are treatments for all patients with plasma cell neoplasms. Surgery may be used in certain cases. Chemotherapy uses drugs to kill cancer cells.