Adding deprenyl to this program increased my dopamine levels beyond the desired window and I had to adjust my Sinemet downward. It was difficult to weather the process, but I eventually got myself off of Sinemet and Inderal and am very pleased with my program now. A number of other people on the program have lowered but not given up these other drugs. These drugs are addictive. This addiction leads to withdrawal symptoms when you try to go off them.
Many people are absolutely terrified of going through that withdrawal.
Instead of riding through it and letting the body get over the addiction, they panic and run back to the drug that is causing it in the first place. Tracking my own reactions to the substances I was taking is what led me to my current program. For myself, I think it was well worth the effort, both of keeping the journal and in withdrawing from standard Parkinson's medications. One of the things that I have learned is that some Parkinson's disease is a result of a defect in mitochondrial DNA in the area of the antioxidant defense system. Losing the antioxidant defense system for a highly energized system such as the dopaminergic nervous system might be likened to losing the grillwork and bricks that surround your fireplace, leaving the sparks and flames to set fire to your house.