It may be used as adjunct in the treatment of chronic urticaria. Hydroxyzine is used for control of nausea and vomiting, treatment of acute alcohol withdrawal symptoms and asthma. It may be used for its sedative effects after general anesthesia. Hydroxyzine is not as widely used as it once was. It is a non-sedating drug.
Pamoate salt is believed converted to hydrochloride in the stomach.
Additive anticholinergic effects with other drugs possessing anticholinergic properties, including antihistamines, antidepressants, atropine, haloperidol, phenothiazines, quinidine, and disopyramide. Induce vomiting or gastric lavage. Do not use epinephrine to control hypotension. Be prepared to provide respiratory support as necessary. Facts and Comparisons, p. 193.