This increases with age. Many of the markers of age are simply due to insulin resistance and higher insulin levels. Excess insulin is a powerful growth factor and makes cells turn over more frequently, shortening their life span. Excess insulin also inhibits the actions of L-Carnitine , one of the body's premier energizers. Excess insulin inhibits glucagon release.
Glucagon regulates blood sugar levels.
Without glucagon the body uses cortisol which ages it rapidly. Insulin resistance or the inability to use insulin. When faced with resistance the body makes even more insulin in hopes of overpowering the cells. Resistance is caused by eating too much carbohydrate and by a lack of essential nutrients. We are not genetically programmed to eat carbohydrates and it shows in our over stimulated insulin production.