Patients may be febrile. Importantly, conjunctival involvement may lead to blindness. The clinical presentation of Stevens-Johnson syndrome is often easily recognizable. Herpetic infections Diseases with oral ulcerations Vesicobullous Diseases in the Differential Diagnosis of SJS Pemphigus vulgaris often presents with facial and trunk flaccid bullae. Mucosal lesions are often seen as in this image.
Paraneoplastic pemphigus is another variant pemphigus.
Interestingly, erythema-multiforme like lesions may also be seen in this condition. Bullous Pemphigoid presents with urticarial lesions, tense bullae, and erosions. Mucosal lesions and crusted erosions are sometimes seen. Bullous lupus erythematosus is an unusual manifestation of systemic lupus erythematosus that should be given diagnostic consideration in the appropriate clinical setting. Disseminated herpes zoster may be seen in immunocompromised patients as in this patient with Hodgkin's Disease with vesicles and erosions on the trunk and leg.