The airport exit road takes you to I64 East. 64 East to the exit to Route 104. Route 104 will join with Route 17 in Chesapeake. Take route 17 south into Elizabeth City. There you will make a left turn just before the Holiday Inn.
Highway signs lead the way nicely.
Weeksville road will take you directly to the campus after about 5 miles. The ECSU campus will be on your left at the stop light. Go through the stop light and make the first left turn directly onto campus. You will be on University Drive. Go to the end of University Drive and make a left turn onto Hollowell Drive.