Withdrawal of the fluid takes about two minutes, and the body replaces it within about 12 hours of the procedure. Care is taken when extracting this fluid to avoid contamination of the sample with maternal blood, which would invalidate the results. Typically, women perceive the needle puncture as a feeling of pressure, usually while the fluid is being withdrawn. Fear of the needle may make the procedure seem more painful than it really is. After the procedure, women may experience mild cramping.
Rest is recommended until the cramping has subsided.
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