Experts from pharmaceutical industry with considerable experience in this area will present their views and participate in the discussion. Nowadays, pharmacology and toxicology, both in vitro and in vivo , are essential to exploit fundamental knowledge for the development of drug candidates. As a consequence, both discplines are more and more applied at an early stage of drug design to guide synthetic strategies. The course encompasses basic and advanced aspects of lead finding, pharmacology and toxicology to provide research chemists in the pharmaceutical industry with the appropriate background for their daily practice. Topics include the impact of molecular biology, combinatorial chemistry and molecular modelling on drug research, as well as a thorough introduction in pharmacodynamics, pharmacokinetics and toxicology.
New topics are assay development, molecular diversity and genomics .
In addition, three case histories will give a flavour of chance and strategy in drug development. Please note that the course is fully booked at the moment.