Ketoconazole increases indinavir concentrations. The dose of indinavir should be reduced. Phenobarbital may reduce indinavir concentrations by enhancing hepatic metabolism. Phenytoin may reduce indinavir concentrations by enhancing hepatic metabolism. Rifabutin is likely to reduce indinavir concentrations by enhancing hepatic metabolism.
Rifampin is likely to reduce indinavir concentrations by enhancing hepatic metabolism.
Indinavir decreases stavudine concentrations. Indinavir increases trimethoprim concentrations.