The recommendation for women is to start with 1 tablet in the evening for 2-3 days. If there are no side effects, increase to 1 tablet AM and 1 tablet PM for 2-3 days. If there are no side effects, increase to 1 tablet AM and 2 PM for 2-3 days. In 6-9 months, the connective tissue will be remodeled to a more youthful state, and the dose can be reduced to 1 tablet daily. For men, the maximum dose is 2 tablets per day.
Relaxin increases serotonin levels.
Most fibromyalgia patients are also taking St John's wort or medications such as Elavil, Paxil, Prozac or others that raise serotonin levels or block serotonin uptake. It is necessary to consult with your physician so that medications can be reduced if necessary to avoid a hyper-serotonin situation. That would not be so good. Hopefully it will be possible to eventually do without the medications. EMEM3, and other units are being reported to help.