Some however, present with aggressive disease and live less than 2 years. Symptoms of CLL frequently depend on the stage of disease. Early in the disease, red blood cell and platelet counts are normal. However, examination of the blood shows an accumulation of leukaemic lymphocytes. Bone marrow examination also reveals leukaemic lymphocytes.
Lymphocytes belong to the white blood cell family.
Their normal function is to fight infections. Proliferation of the leukaemic cells interferes with the immune system. Fever, loss of weight and appetite are common symptoms during all stages. Furthermore, it is common for lymph nodes to be enlarged due to leukaemic cells infiltrating the lymph nodes in the groin, armpits or neck, along with involvement of the spleen and liver. Organ enlargement may cause abdominal fullness, discomfort or pain.