The main difference is in the bleeding pattern that results. You can take a daily tablet of estrogen or wear a skin patch twice a week.
Progestogen is taken in pill form.
Over 90 percent of women will have a monthly period on this regimen if the uterus is intact. Note your bleeding pattern, which should occur after you stop taking progestogen. Estrogen is taken from the first to the 21st day of the cycle, and progestogen for the last 12 or 13 days of the cycle. Over 90 percent of women who have not had a hysterectomy will experience a withdrawal menstrual period in the interval between ending one treatment and beginning the next. However, bleeding usually lessens over time and may disappear altogether.