Try to find out what they did last weekend, or what they're doing this weekend. Ask about a movie or television show. Avoid politics, their personal problems and for goodness sakes don't lament your personal problems. You're on a mission. But I can assure you the mission is most likely to be accomplished if you have made a friend before you make the presentation.
People love to talk about themselves.
Getting a prospect to talk about themselves will give you a chance to find common ground, establish rapport and increase your chance to make a sale. If you establish common ground with the prospect, they will like you, believe you and buy from you. The best way to win the sale is to first win the prospect. You are responsible for the sale. Take the responsibility test and find out.