Generalisations are only possible where one finds clear-cut parallel cases.
Biogeography can limit generalisation considerably. Even in Central America this might not be of great importance when considering certain harmless transgenes, however, it might well not be judged as being harmless in other cases. This means that GMO's will be bound to agricultural systems in an optimal way. Predictability must be possible, although it is known from experience with invasive species, that there is always the possibility of unpredictable events. It must be possible to take back escaped transgenes.