There may be some discomfort. Granular Dystrophy, as the name implies, produces central granular deposits. Macular Dystrophy produces central round, indistinct opacities. The signs above can be seen by an eye doctor using a biomicroscope. Negative staining may be seen when fluorescein dye is instilled in the eyes.
Most corneal dystrophies are autosomal dominant.
Macular Dystrophy is autosomal recessive. If there is significant clouding, causing a significant loss of vision, penetrating keratoplasty may be necessary. In addition, Excimer laser may be used. The patient usually becomes more symptomatic with time. If associated with corneal erosions, the affected area is susceptible to infection.