In the second phase the data base was expanded to include 78 cases currently an medication randomly drawn from a crisis treatment program and from a questionnaire regarding the use of Prozac. Phase three employed a modified case-control methodology utilizing medical record. This study reports on the use of medications to assist in managing the behaviors of persons with PWS of all ages. An epidemiologic surveillance methodology framed the investigation. A 17 question structured interview format was administered to primary caregivers regarding present and past use of medications.
Most subjects are on no more than two medications.
Dosage levels and schedules are often idiosyncratic including one subject who is administered Dexedrine on odd days and Ritalin on even days. Details of brand name medications by class will be identified together with a more extensive analysis of the relationship between use of medications and symptomatology, effects by sex, and positive and negative impact.