Older individuals with ATD often develop kidney dysfunction in later childhood which can lead to kidney failure in adulthood. Radiographically, the pelvis in individuals with ATD and EvC are similar. Some geneticists feel that ATD and EvC may actually be due to changes in the same gene and so represent different manifestations of the same gene. ATD is also inherited in an autosomal recessive manner. These infants die at birth because of respiratory distress.
Inheritance is autosomal recessive.
References Brueton, L.A. et al. Francomano, CA, et al. Mosby-Year Book, Inc. 1993, pp. Scott, C.I. Dwarfism.