Diagnosis of that condition is based on a family history, medical history, and thorough physical evaluation. The history and physical examination findings will determine whether further laboratory and diagnostic procedures are necessary. Considerations Prominent creases, called flexion creases, normally appear on the palms of the hands and soles of the feet as part of the hand print and foot print. The palm normally has three flexion creases. Sometimes, the two horizontal creases fuse to form a single crease, called a single palmar crease or a simian crease.
Many structures develop in the first few months of gestation .
Palmar creases develop early. Abnormalities in palmar creases may indicate the presence of other associated abnormalities. A single palmar crease or simian crease appears normally in approximately 1 out of 30 people. The information provided herein should not be used for diagnosis or treatment of any medical condition. A licensed physician should be consulted for diagnosis and treatment of any and all medical conditions.