Removal of the ingested substance by gastric lavage or emesis as soon as possible after ingestion is considered effective. 1 Intravenous atropine is of great diagnostic value, and is a specific antidote in the diagnosis of organophosphorus poisoning. It should be promptly used when the latter is suspected. Once the pupils dilate to a normal size, atropine is stopped. It is important to remember that atropine has no effect on severe muscular paralysis.
Respiratory support is therefore vital in OP patients.
Pulmonary edema is countered by intravenous Lasix 20-40 mg, and by using a mechanical ventiltor to give oxygen under pressure. Pralidoxime is not easily available. Treatment with pralidoxime should be repeated after 30 minutes if respiration does not improve. Prognosis is good if prompt action is taken as soon as the diagnosis is made. Any delay in starting treatment may be costly.