A yellow-white zone of lipid may be seen central to the area of thinning. This condition is rare. The condition may be seen at any age, but is most common in patients between the ages of 20 and 40. The disease usually begins superonasally with fine punctate opacities in the anterior stroma with a lucent interval separating the opacities from the limbus. Over time the lesions may extend circumferentially or centrally.
Progression occurs slowly over the course of years.
The typical superior corneal thinning produces against the rule astigmatism. Thinning may become severe enough to produce corneal perforation. If not very severe, against the rule astigmatism may be treated with glasses or contact lenses. Severe astigmatism, impending perforation, or perforation may be treated with lamellar or eccentric penetrating corneal grafts. All rights reserved.