You would want a protein that is not going to be degraded or inactivated by phosphorylation during its slow journey through the cell. While continuing this work with RET, Pike is exploring a new observation. She found that a lipid that is important in signaling is highly concentrated in caveolae. We used to think that signaling components were spread throughout the membrane and had to find each other to signal. Now it seems they're clustered in one place.
Pike looks forward to more unexpected findings.