Many conditions of bone, both common and uncommon, are considered under the general category of genetic and metabolic diseases. These conditions may involve the skeleton in general, effecting almost all bones. They may also effect only certain regions, or even a single bone. The Cleveland Clinic offers exceptional resources for education, evaluation and treatment related to these conditions.
Osteoporosis is a generalized loss of bone that occurs throughout the skeleton.
Osteomalacia is a condition in the quality of bone is compromised by a failure of bone to take up a normal amount of calcium. Paget's Disease is a benign condition that usually effects only one part of the skeleton. This condition can be painful, but is not always painful.