Preeclampsia is a multisystemic disorder of unknown etiology.
Recently, endothelial damage has been implicated in its cause. The objective of this study was to determine the role of interleukins in the etiology of preeclampsia. It is concluded that the elevated maternal plasma IL-10 concentration in preeclampsia may be a protective response to maternal immunorejection. Preeclampsia is a multisystemic disorder of pregnancy, with the clinical diagnostic features of hypertension and proteinuria. Although the cause of this disorder is still unknown, current concepts of preeclampsia suggest that generalized dysfunction of the maternal vascular endothelium is a central pathogenic feature.