Without the medications, almost all study participants had difficulty keeping their lost weight off. Both medications are approved by the Food and Drug Administration as appetite suppressants. While the extended-release form was approved by the FDA, it has not been put on the market by A.H. Robins. Start patients on 15 mg phentermine after breakfast and 10 or 20 mg of immediate release fenfluramine one hour before the evening meal. Allow patients a week or two to get used to the medications and their possible side effects.
Most unpleasant effects decrease or disappear within several weeks.
Unpleasant effects may reappear temporarily. Phentermine is also available as Fastin, by other trade names, and generically. The use of fenfluramine and phentermine together and for a long duration is a new and somewhat non-traditional therapy for obesity. Fenfluramine and phentermine are appetite suppressants, and have been available as FDA-approved prescription medications for a number of years. They do not alter one's genetic make-up, which may be a contributing cause of obesity.