Vitamin and iron supplements are advised if nutritional compromise exists. If esophageal strictures develop, a blenderized diet is recommended. Avoid unnecessary trauma to the skin. Loose fitting clothing and soft, well-ventilated, leather shoes are advisable. Since increased ambient temperatures exacerbate most forms of EB, a cool environment is important.
Preventive measures are the main key to successful management.
The challenge requires cooperation of patients, parents, and caring physicians. Appropriate genetic counseling is the responsibility of the treating physician as it is in any inherited disorder. Accurate diagnosis requires careful evaluation of the patient, appropriate family histories, cutaneous biopsy, electron microscopy, and immunofluorescent study. A newborn with bulla of the finger, usual site of blistering secondary to trauma. Congenital localized absence of skin and associated abnormalities resembling epidermolysis bullosa.