Ischemia is the result of a perfusion-dependent imbalance between supply and demand.
Possible ischemic symptoms include chest, epigastric, arm, wrist or jaw discomfort with exertion or at rest. The discomfort associated with acute MI usually lasts at least 20 min, but may be shorter in duration. The discomfort may develop in the central or left chest and then radiate to the arm, jaw, back or shoulder. The discomfort is usually not sharp or highly localized and may be associated with dyspnea, diaphoresis, nausea, vomiting or light-headedness. The discomfort is not affected by moving the muscles of the region where the discomfort is localized, nor is it worsened by deep inspiration.