Her physical exam should also include a test for heartworms in areas where this is a problem. She should be given all her booster shots at this time too. Because of an increase in the incidence of brucellosis in dogs, a serum agglutination test should be done before mating. This test is available in veterinary clinics and can be run from a blood sample in minutes. Also, before mating, the bitch should be checked for worms.
Round worms are difficult to avoid in puppies.
Other parasites should also be vigorously treated. A bitch with an active parasite infestation is less likely to whelp healthy puppies. Before she comes in season is the time to find a stud dog that will enhance your bitch. Get several breeders' opinions of a good choice for a stud dog. If they only recommend dogs owned by themselves, take their opinion with a grain of salt.