The periosteal osteoblasts begin to form bone plates around the spongy bone middle. Think of an oreo cookie - the filling is the spongy bone, and the cookies are the compact bone. Endochondral Ossification Remember that endo means within, and chon is our root word for cartilage. Endochondral ossification occurs within cartilage bone models, and occurs in most bones of the body. This process is somewhat more complicated than intramembranous ossification because the cartilage must be replaced with the bone.
Ossification begins at a primary ossification center.
In long bones this is in the center of the diaphysis. 2 and 3. The osteoblasts secrete osteoid around the cartilage, forming a bony collar around the diaphysis. This again is not the mature bone, but is known a woven bone, which will be eventually replaced by compact bone. 5 Chondrocytes within the cartilage bone will undergo hypertrophy, or an increase in cell size.