Fatalities to humans are rare. The gila monster and the closely related Mexican beaded lizard are the only kown venomous lizards in the world. These heavy bodied lizards are easily distinguished from nonvenomous species by the bead-like surface and yellow or coral colored pattern of their skin. They are described as docile reptiles, not prone to attacking humans unless significantly agitated. State laws protect these fascinating animals from being captured or held in any manner.
Gila monsters have the well-earned reputation of delivering a tenacious bite.
Most serious envenomations have occurred when the lower jaws have secured a firm hold on the victim for several minutes. The bite is described as extremely painful, although pain is generally confined to the area of the bite initially. Victims may also experience localized swelling, nausea, vomiting, hypertension, weakness, faintness, excessive persperation, chills, and fever. When bitten, it is important to disengage the lizard as soon as possible. This may be done by placing a strong stick between the bitten part and the back of the lizard's mouth and pushing against the rear of the jaw.