In 1991, the FDA still found Musk ambrette in skin contact products. Musk xylol is found in water ways and aquatic wildlife. It being found in human fat tissue and breast milk. In spite of this the IFRA has made no restrictions or recommendations concerning its use. Only a small segment of the population has adverse effects from fragrances.
Fragrance is one of the most common causes of adverse reactions to cosmetics.
Asthma rates have doubled in the past twenty years. In 1994 there were over 14 million asthmatics. Each year over 35 million people suffer from sinusitis. Fragrances are general irritants that contribute to the incidence of sinus problems. Migraines effect as many as 25 million people.