Up to now 8 variants of such epithelial mosaics in different animals have been already found experimentally. The discovery of other ones is possible in future. Also, some of them may appear in the future evolution of multi-cell organisms. The results enable us to initiate the study both topological and metrical aspects of spatial organization of stratified epithelia and to determine the nature and biological reasons of their symmetry. According to the results a model of 3 - dimensional shape and spatial arrangement of cells in pseudostratified epithelial sheets were developed.
Preliminary data seem to confirm the models and indicate the importance of the investigation.
The present investigation brings us to the conclusion that tissue topology transformation during carcinogenesis one may be compared with phase transformation in physics and described quite accurately. The analysis of transformation of cell mosaics symmetry may provide the key for understanding of carcinogenesis and the role of tissue elemental units in these processes.