Resistance may develop to its efficacy. A tetracycline antibiotic that is effective against Plasmodium. It is used for multi-drug resistant cases of malaria. The pharmacology of doxycycline will be covered in the anti-biotic section. An older preparation that has been replaced by newer agents with fewer side effects.
Quinacrine is primarily in the treatment of giardiasis, covered below.
A naturally occurring product currently being investigated. Its short half-life precludes its use as a prophylactic treatment. It is effective only against blood schizonts. The mechanism of action is not known. Side effects include minor GI irritation.