A MODY diagnosis should not be confused with the increasing appearance of regular type 2 diabetes among adolescents, which researchers are attributing to poor dietary habits and a decline in physical activity. Beta-cells in the pancreas that produce insulin are gradually destroyed. Eventually insulin deficiency is absolute. Without insulin to move glucose into cells, blood glucose levels become excessively high, a condition known as hyperglycemia. Because the body cannot utilize the sugar, it spills over into the urine and is lost.
Patients become dependent on administered insulin for survival.
Diabetes Secondary to Other Conditions Conditions that damage or destroy the pancreas, such as pancreatitis, pancreatic surgery, or certain industrial chemicals can cause diabetes. Polycystic ovaries are highly associated with diabetes. Certain drugs can also cause temporary diabetes, including corticosteroids, beta-blockers, and phenytoin. Diabetes and Endocrinology Treatment Updates. Medscape Inc., August 17, 2000.