I.A. Strokov, N.A. Kozlova, Yu. Intravenous infusion was administered once daily during a period of 3 weeks. Electroneuromyography were performed. Parameters of oxidative stress and electroneuromyography improved significantly in the main group of patients, while these in placebo group remained without changes. 50 patients with Duchenne Becker muscular dystrophy participated in this randomized double-blind controlled trial and up to now 3 of them were on the program about 1,5 year and 24 of them about a year.
Prelimenary results show some beneficial effects in the absence of manifest side-effects.
It was proved that clinical improvement in the patients state correlated with a decrease in the contents of both total protein and immunoglobulins G , A , M in cerebrospinal fluid. It was suggested that the removal of these humoral factors had decreased a degree of inflammatory and demyelinizating processes in inflammatory demyelinizating polyneuropathies and had improved, thereby, the results of the treatment. The aim of the study was to determine indications and contraindications for prescription of neuroleptics in opium addiction and to study their influence on the state of the patients at different stages of the treatment. The duration of the addiction was from 6 months to 18 years. It was found that therapy with neuroleptics is a necessary component of a combined treatment in the acute phase of the withdrawal syndrome and at the first stages of the following therapy.