The primary carcinoid tumor is usually derived from the enterochromaffin cells of the midgut and is located most frequently in the terminal ileum. Carcinoid tumours generally secrete various amounts of indoles.
Most patients experience several cyanotic red flushes over the face and upper chest.
The most common complaints, however, are abdominal discomfort, frequent diarrheal stools, loss of body weight and metastatic lesions in the liver. Attempts were made to overcome this problem by a combination of ion exchange chromatography and fluorometry. These methods, however, lack sensitivity and are time consuming. Both methods require solvent extraction because of the numerous interfering compounds present in urine. Dilution Reagent 1 vial 4 ml, ready for use, contains N,N-dimethylformamide.