After entering the blood by absorption through the lung membranes, they are taken up and held in the body's fat stores, and in organs with significant fat contents such as testes, ovaries, brain and mother's milk. I followed up through adulthood the pups I had given these drugs the day before they were to be delivered. The pups looked pretty normal in appearance and size when they were born. It wasn't until puberty that it was evident that they were underweight. We started to find hormonal imbalances that decreased testes weights, which started just before puberty but persisted up into the adult period of these animals who had only been exposed through their mother on the last day of her pregnancy or through her milk the first six days of the nursing period.
Milk is so very fatty that it's a storage depot for unmetabolized cannabinoids.
It has now been shown in monkeys, rats, sheep, and mice that THC definitely gets through milk in largely unchanged form. 2.3 Alcohol, Nicotine and Caffeine Alcohol will pass into the breast milk and the concentration in the mother's milk is usually about equal to that in her blood. However, an occasional intake of alcohol in small quantities does not contraindicate breast feeding. Chronic alcoholics and occasional heavy drinkers should not breast feed, as their infants may suffer from 'pseudo-Cushing's syndrome'. The characteristic findings of this syndrome in infancy are excessive weight, short stature, and moon-shaped face.