Hypertension is common in hyperparathyroidism.
Iseki, Massry, and Campese noted that PTH had a permissive role in the hypertension associated with hypercalcemia. Peter Pang and colleagues have suggested the existence in SHR rats of a parathyroid hypertensive factor, distinct from PTH, although it's specific structure remains to be identified. How hyperparathyroidism might cause hypertension is otherwise unknown, as PTH has a hypotensive effect when injected into animals. The increases in MAP correlated with increases in platelet calcium levels. Whether PTH has a role in the hypertension of uremia remains unknown.