Typically the default split level, and appearance of the HTML pager header and footer will be customized. Using relative icons avoids have latex2html generated HTML pages use NRAO as an icon server. There are several methods for producing links to other documents. The URL and path to labels file need to be relative paths. The order of when documents are run through latex2html is important for external cross referencing.
Funny things can happen if labels are multiply defined.
Cross referencing from an HTML document to something in the User's Reference Manual or another LaTeX based document is possible. This is not recommended since latex2html generated file names and anchors will likely change. A word of caution, relative links in the docs tree may be different than those found in a programmer's code tree. The implement directory is missing in the docs tree. The help system is a special type of LaTeX document.