46 capsid the protein coat of a virion , composed of large multimeric proteins , which closely surrounds the nucleic acid. 1 cholestasis impairment of bile flow at any level from the canaliculus to the duodenum. The clinical condition resulting therefrom, characterised by icterus and pruritus, is due to the accumulation in blood and tissues of substances normally secreted in bile, particularly bilirubin , bile salts, and cholesterol. 1 endemic continuously prevalent in some degree in a community or region. 46 enzyme any protein catalyst, i.e. substance which accelerates chemical reactions without itself being used up in the process.
Many enzymes are specific to the substance on which they can act, called substrate.
Enzymes are present in all living matter and are involved in all the metabolic processes upon which life depends. Thus an epidemic is a temporary increase in prevalence . Its extent and duration are determined by the interaction of such variables as the nature and infectivity of the casual agent, its mode of transmission and the degree of preexisting and newly acquired immunity. 46 epitope or antigenic determinant. The small portion of an antigen that combines with a specific antibody .