He observes if there is any unexpected benefit such as clearing of sinuses, decrease in allergies, increase in energy, etc. Should any chronic problem be benefited, then the dose is decreased to the minimum amount producing the effect. Otherwise a dose such as 4 to 10 grams a day divided in 3 to 4 doses is recommended. In addition, the patient is told to increase the dose on stressful days.
Most patients can easily sense their ascorbate needs.
Patients who take ascorbate in large amounts over a long period of time should probably supplement with vitamin A and a multiple mineral preparation.