The second strategy is based on proteins that act directly against the nematodes. We have modified a plant proteinase inhibitor from rice by protein engineering. Development of H. schachtii on Arabidopsis . Effect of hairy roots expressing a cystatin on the growth of Globodera pallida . Red growth curve describes those animals collected from transgenic plants expressing the cystatin, the blue growth curve describes animals collected from wild type plants.
Pictures show representative animals collected from the two sets of plants.
The density of animals, their growth, development and fecundity were all affected. This technology is inherently safe and based on proteins that occur naturally in seeds consumed by humans. One objective is to provide effective nematode resistance without the subsistence farmer needing to be aware of nematodes in his soil. We collaborate on developing world issues with scientists Bolivia, Peru and India. We offer an excellent research environment to molecular biologists seeking training in interesting problems with important applications.