The following slide shows the ultrastructural appearance of a large brush of cytoplasmic intermediate filaments characteristic of rhabdoid cells. The cell of origin remains unknown, and whether MRT is a neuroglial neoplasm closely related to PNETs is also unclear. While a significant minority of rhabdoid tumors contain mesenchymal or epithelial components, pure PNETs contain morpologically dissimilar connective tissue and have not been found to have similar differentiated epithelium. Thus in these two cases we chose to treat only the posterior fossa tumor bed. The sole patient with evidence of disease did not receive a complete resection.
Optimal therapy appears to require complete resection followed by radiotherapy.
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