At the Statens Serum Institut, we are focused on the isolation of proteins from M. tuberculosis which will serve as improved diagnostic reagents and vaccine candidates. My role is to improve our current understanding of the immune response to M. tuberculosis. This should enhance our ability to determine what constitutes long term protection, what responses are most desirable for protection, and how best to invoke those responses. This work will speed the development of these urgently needed reagents. I also co-ordinate several ongoing projects in Africa examining human responses to antigens from M. tuberculosis with the goal of selecting candidates for future vaccine and diagnostic use.
Publications Here is a list of recent publications.
The abstract, and in some cases a link to the full text version, can be obtained from the National Library of Medicine database, by clicking on the links below. T. M. Doherty, Munk, M. E. and P. Andersen. A Historical Perspective on the Role of Science. The Next Generation of Tuberculin . Targeted by these Agents.