This method of absorption by-passed the liver and was delivered to the tissues unchanged. Although this method of delivery was discovered over 20 years ago, physicians still prescribe progestins with all their side effects and lack of similarity to the much needed hormone, Progesterone. Although 25 mg of progesterone delivered transdermally protects a woman against osteoporosis, it is not clear if this amount will protect her uterus from endometrial carcinoma if she is also on estrogen replacement therapy. If the Progest cream is used with estrogen replacement, I recommend a yearly endometrial biopsy to screen for endometrial cancer. With osteoporosis being responsible for so many deaths among women, it is important to consider the safest treatment plan to prevent this debilitating disease.
Progesterone is a safe option.
No side effects. Inexpensive and easy to administer. Many women are frightened to take estrogen or progesterone because of the possible increased risk of breast cancer, It is not clear if hormone replacement therapy increases the risk of breast cancer. It may be an imbalance in how estrogen is presented to the body. This supports the importance of diet and a balanced bowel flora in the intestines.