The pH can be experimentally manipulated to induce macromolecular synthesis in the absence of sperm binding. After the sperm contents enter the egg, most of the mitochondria dissolve. Therefore, mitochondrial genome is primarily from the maternal parent. In most animals, the centrosome is contributed by the sperm. The mouse is an exception.
Fertilization triggers the completion of meiosis and the female pronucleus is formed.
Upon meeting, the two envelopes break down and the chromosomes orient for the first mitosis. These rearrangements can have important developmental functions. Important concept that will be revisited in future lectures.