The clinical response to cromolyn and nedocromil is less predictable than the response to inhaled corticosteroids. Both compounds have a strong safety profile. They can be used for long-term prevention of symptoms and preventive treatment prior to exposure to exercise or to a known allergen. Long-Acting Inhaled Beta 2 Agonists . Salmeterol is not to be used for treatment of acute symptoms or exacerbations.
Patient education is critical.
Patients should be instructed not to stop anti-inflammatory therapy while taking salmeterol even though their symptoms may significantly improve. Sustained-release theophylline's main use is as adjuvant therapy, and it is particularly effective for controlling nighttime asthma symptoms. It is not generally recommended for exacerbations. Serum concentration monitoring is mandatory. Leukotriene Modifiers .