RES GOLD TM consists of a 20 nm opsonized gold colloid. This reagent is taken up by macrophages of the liver and spleen and can be used for a variety of applications including quantifying Kupffer cell activation, blockade, dysfunction, and distribution. In combination, these kits provide great experimental design flexibility. The samples are then sent to BioPAL for neutron activation and analysis.
Researchers can expect assay results within ten working days.
The ability to re-assay stored samples is a major advantage for pharmaceutical development. Currently, RES GOLD TM is only available as a gold colloid. However, BioPAL is actively developing new isotopic markers that will allow researchers to make multiple measurements in RES activity as a function of time, disease, or intervention within a single in vivo study.