It also has been found to act directly on blood vessels, leading to vasospasm. It is primarily metabolized in the liver and undergoes significant enterohepatic recirculation. Clinical effects occur within minutes and can last several hours. The American Association of Poison Control Centers' 1998 report documents 372 exposures to phencyclidine and 2 deaths. Fatality occurs from seizures or apnea.
Most deaths result from trauma or respiratory complications.
No scientific evidence has demonstrated that effects or outcomes of PCP toxicity are dependent on race. They may report bizarre agitated behavior in the patient. Miosis is common in conjunction with a blank stare. Respiratory problems are rare and are related to inhalation, co-ingestants, or seizures. A myriad of neuropsychiatric presentations may be encountered.