It has recently been shown that they are also capable of producing antibodies to Neurotransmitters including Endorphins, Enkaphlins and Serotonin. These neurotransmitters are important in ovarian and uterine function. Treatment of the hyperthyroid or hypothyroid conditions does not change nor improve the autoimmunity directed against the thyroid gland. Treated women still suffer poor stimulation cycles, infertility, IVF failures, implantation failures, donor egg failures and miscarriages. Diagnosis and treatment of the autoimmunity involving activated natural killer cells and antibodies to hormones and neurotransmitters are necessary.
Immune treatment is also necessary before a successful pregnancy is realized in most women.
This treatment must be given preconception. Many women require three months of preconception treatment before it is safe to begin a cycle of conception. The treatment must continue for at least 10 weeks into the pregnancy. Many women have a very hard time believing this and are very resistant to stopping any of the medications that have allowed them to progress to this point in their pregnancies. If there is an overactive or underactive thyroid condition identified, then further autoimmune tests are necessary as described for women with reproductive failure.