Mouth sores can occur on the tongue, the sides of the mouth or in the throat. Mouth sores or bleeding gums can lead to an infection. Brush your teeth gently after eating and at bedtime with a very soft toothbrush. If your gums bleed, use gauze or your finger instead of a brush. Make a mouthwash with teaspoon baking soda or salt in 1 cup warm water and rinse several times a day.
Hair loss is rare with plicamycin.
Your hair will grow back once you stop treatment with plicamycin. Colour and texture may change. Use a gentle baby shampoo and soft brush. Avoid hair spray, bleaches, dyes and perms. Your skin may redden, thicken and darken in some areas including your face.