Autosomal recessive with variable expression. The fetuses demonstrate growth restriction and hypotonicity. Biochemical studies using blood cells and fibroblasts can confirm the diagnosis by detection of reduced peroxisomes and abnormal lipid metabolism. Note the enlarged size of the eye. Down syndrome is commonly misdiagnosed, due to the overlapping of several structural findings 3 08D0C9EA79F9BACE118C8200AA004BA90B02000000080000000E0000005F005200650066003400340030003900340031003900300036000000 .
Most infants die within the first year.
Termination of pregnancy can be offered before viability. Standard prenatal care is not altered when continuation the pregnancy is opted. Confirmation of diagnosis after birth is important for genetic counseling. Subependymal germinolytic cysts in Zellweger syndrome. Zellweger syndrome in Smith s recognizable patterns of human malformation.