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Major anesthetics circulate through the entire body and have stronger actions on the nervous system.
Major anesthetics commonly cause nausea upon waking. Administration of 1 gram of powdered ginger root in capsules one hour before surgery has led to reduction in nausea and vomiting as effectively as the antinausea drug metoclopramide in a double blind study. These results have been independently confirmed. Due to ginger's potential effect on blood clotting, a surgeon should be informed about ginger use prior to surgery. Major anesthetics infrequently cause liver damage.