God gave us an example at Creation as Christ did in His life on earth. This was one reason for the Sabbath. The Sabbath is also a symbol of the eternal rest we shall have with Jesus in the earth made new. But it is not just the weekly rest that we need. There is nightly rest.
Most people require six to eight hours of sleep.
It is also good to have a few breaks during the day, not only at, but including mealtimes. Sometimes we also need to learn that we cannot do it all ourselves, and we need to turn everything over to the Lord, and to rest in the Lord. But after sin, it became even more necessary. Then, too, if we do not work and exercise our body, it becomes stiff and weak, and, in some cases, a limb or organ may shrivel up and become useless. And, vice versa, through use or exercise, a limb or organ often may become healthy again, like a broken leg that has to be kept in a cast for a long period of time.