Every one dies. Disease and death are parts of life, not foreign bodies to be eliminated. Dreaming of an America free of disease, free of drugs, free of crime is as delusionary as dreaming of life without death. Some people think that science can overcome all obstacles. Science can give us power over nature, but it cannot give us power over human nature.
People are healthier and live longer than they did in the past.
Understanding human behavior is a matter of common sense and morals, not medicine or science. The Founding Fathers took it for granted that limits on human appetite, especially for power over others, is a moral good. That is why they insisted that good government is limited government. The Founders were pious persons. If you want to honor those values, you must choose your obligations wisely, so that fulfilling them will be a delight, not a duty.