Digital stock does not retain as much quality as the original transparency. Higher quality images are available. More control over image usage reduces likelihood of competing use of an image. Costs can be considerably higher and licensing is much more restrictive. Transparencies must be returned after they are used.
Enlargements are less expensive.
Manipulation of the traditional image is limited. Digital imaging allows for more versatile image editing. Commercial quality inkjet prints are sharper and more detailed than traditional prints. Retouching and editing an image can be time consuming. Commercial quality scanning and printing can be up to twice as expensive and requires an extensive investment in computer hardware and software.