However, whether calcium affects nadolol in this manner is unknown. Until more information is available, people on nadolol should take calcium supplements an hour before or two hours after the drug. Until more is known, individuals taking nadolol should talk to their healthcare practitioner before supplementing with potassium. Taking nadolol completely blocks the increase in both heart rate and blood sugar usually observed in people taking ephedrine, but it does not completely affect its ability to increase calorie-burning. Consequently, nadolol may reduce the potential effectiveness of ephedra in treating obesity and may eliminate other beneficial effects of ephedra, such as the reduction of asthma symptoms.
More research is needed to explore the interactions between ephedra and amphetamines.
The active compound in white willow, salicin, is converted to salicylic acid in the body. Taking salicylates with other beta-adrenergic blocking drugs has resulted in decreased absorption of the drugs. Therefore, until more is known about the interaction between white willow and nadolol, they should not be taken at the same time. Burnham TH, ed. In Facts and Comparisons Drug Information.