Fetus Achondroplasia is a derangement in epiphyseal cartilage growth with loss of normal palisade of cartilage spicules that normally undergoes provisional calcification and then ossification.
Premature ossification makes a bony barrier at the osteochondral junction.
Only endochondral bone formation is affected. Long bones are characteristically short and wide. Spine length is normal, but kyphoscoliosis is present. Skull is large in comparison to limbs. The disorder is inherited as an autosomal dominant condition.