Halichondrin B, isolated from the sponge, Lissodendoryx species, is found in New Zealand. It is in preclinical development. Several agents isolated from microbial sources, mainly Streptomyces species, are in preclinical or clinical development for the treatment of cancer. Rebeccamycin analog is in phase I and II clinical trials for several types of cancer, including lymphomas and neuroblastoma . I clinical trials for patients with advanced cancers.
Hematologic cancers are cancers of the blood or bone marrow , including leukemia and lymphoma.
I clinical trials for solid tumors.