The group is based clinically in vascular surgery and is headed by Bo Risberg MD, PhD, professor of surgery at G teborg university. Goal The principal research goal is to elucidate local factors and their regulation in the vascular wall responsible for thrombosis, fibrinolysis and intimal hyperplasia.
Intimal hyperplasia is analyzed as a response to injury and flow variations.
Hot spots Signal transduction in endothelial cells in response to thrombin stimulation. Relationships between the inflammatory reaction and fibrinolysis in the atherosclerotic plaque. Plasmin and apoptosis. Local fibrinolytic response in the ischemic leg. Viruses and atherosclerosis.