Based on the Product Insert information and other sources, the following is a list of Pro's and Con's about this medication. No hypoglycemia if this drug is used as the only diabetic medication. Most people will find it easier to lose weight. Only a VERY modest decrease in glycohemoglobin at recommended maximal levels of 100 mg. Probably this combination should not be tried, except under the care of a physician who is experienced with these medications.
High doses cause abnormal liver enzymes.
Therefore, the manufacturer recommends a maximum dose of 100 mg three times daily. Sulfonylurea drugs and insulin, however, can lower blood sugar levels enough to cause symptoms or sometimes life-threatening hypoglycemia. The risk of hypoglycemia, its symptoms and treatment, and conditions that predispose to its development should be well understood by patients and responsible family members.