Sawada, H., and Esaki. Stains such as uranyl acetate and lead citrate must be used after silver enhancement. DAB and other enzyme substrates are redox active compounds, and the enzymes themselves work by redox reactions. This means that the enzymes, DAB and other substrates, and their products may catalyze silver deposition. I have heard about Gold Enhancement and was wondering if I could use it in my application.
Gold enhancement works very similarly to silver enhancent.
In general, it may be used in place of silver enhancement in any system in which silver enhancement is currently used. May be safely used before osmium tetroxide staining without post-treatment such as gold toning. Low viscosity for easy and accurate mixing of components. Gold Enhancement process is less pH dependent than silver enhancement - Goldenhance is supplied at neutral pH, and you can adjust pH for better sample preservation. As far as we are aware, there are no silver enhancement applications in which GoldEnhance may not be used.