Anti-inflammatories and Fluids. This allows somatic cells to work more effectively. Because of this consideration, these products need to be used early. Oxytocin remains very effective in completely emptying the mammary gland of bacteria and endotoxins if given early and often. Complete and frequent milkouts are very underrated in their usefulness early in infections.
Fluids are important to maintain healthy cell function and circulation.
Cows with acute mastitis need to be encouraged to drink with TLC or intravenous hypertonic saline. Thus treatment strategy must be aimed at the critical links. Physical blockage of udder tissue is a significant barrier to drug action. Chronic mastitis is an udder tissue disease, not a milk disease. Most organisms attach to the cell linings, and have varying abilities to cause deeper tissue damage.