Professor Maher PHL 837 Vascular Physiology and Pharmacology Provides the interested student with a detailed study of the systemic and pulmonary circulations. An emphasis is placed on the physiological and pharmacological regulation of vascular tone. The pharmacological response is examined as the interactions between the physicochemical properties of a drug and the body tissues. The interactions of drugs with whole tissue and individual receptors are explored. Emphasis is placed on analysis of ligand binding data.
Emphasis is placed on the functioning of G-protein linked receptors.
Emphasis is on the systemic site of action for toxins, types of injury produced in specific organs or systems, and the agents that produce such injury. Provides information for the graduate student on the various animal welfare agencies and the proper care and use of laboratory animals involved in scientific experimentation. This course is designed to expose the student to recent developments in the fields of the neurosciences. Topics include receptor pharmacology, blood-brain barrier transport, presynaptic modulation, CNS control of cardiovascular functions, thermoregulation, neurotransmitter pharmacology, and epilepsy. Drug Screening Provides practical training in the qualitative evaluation of drug compounds from the standpoint of type of response and possible site and mechanism of action, based on differential pharmacological characteristics, and the classification of these compounds according to determinative response features into proper pharmacologic categories.