Superoxide dismutases, special enzyme systems are part of this mechanism. Since cancer cells are comparatively active in aerobic metabolism and have low levels of superoxide dismutases, inhibition of these enzymes can kill the cancer cells. 2-Methoxyestradiol, an estrogen derivative is found to selectively kill cancer cells by inhibiting superoxide dismutase. State of the Art Dysplasia of the hematopoietic system has become, in the last two decades, an issue of growing frequency and importance. Enthusiasm is laudable, but certainty is even better.
Oncology is littered with debris, left behind by false interpretations.
Some of this has been reflected in the many brief notes, published throughout the years in CW, which can pride itself of remaining critical and unbiased. Diet Diversity and Composition in Cancer Diet is a complex variable. Epidemiological studies are trying to associate food intake with disease, by evaluating absolute amounts of nutrients consumed during defined observation periods, which may sound scientific and exact, but is far from both. This is not a review that enumerates the pitfalls of such studies, starting with cultural specifics, genetic make-up and individual compliance or rather the lack of it. Recommendations evolve and change, because we tend to believe in trendy advice, based on studies that have a tendency to be incomplete or eventually outright wrong.