This paper describes PDQ-A, the precise digital quantification of retinal angiopathy, via method A, separative colorimetry .
Retinal angiopathy is a leading cause of blindness.
Various agents are continuously being evaluated for rectifying this condition. Accurate measurement of the effectiveness of these drugs is dependent on being able to quantify precisely the degree to which the disease process has been attenuated. A seven step image processing sequence is described that claims increased accuracy of measurement is described. The essential elements of the technique colorimetrically label diseased and healthy tissue imagery and separate these labeled types as far as possible in an RGB color space. Simple thresholding and histogram techniques are then used to compute the fraction of diseased tissue to healthy tissue.