Little can be done to alleviate numbness, but if a patient is especially annoyed by other parasthesias, medications can sometimes be prescribed to address the symptoms. Fatigue Fatigue is the most common symptom of MS, and for many, it is the only disabling symptom. The fatigue experienced by MS patients is more severe than fatigue experienced by other people. It is a neurological fatigue, created by the loss of myelin. The fatigue of MS is both physical and mental, and can be overwhelming in both regards.
Fatigue can make it difficult to concentrate.
It slows the thinking process and makes one forgetful. It can even affect motivation. The other chronic symptoms of MS are made worse by fatigue, and it can contribute to muscle pain and spasms. Fatigue increases with physical exertion, emotional stress and exposure to heat. Weakness Weakness is not the same as fatigue.