Additionally, a person contracting the disease suffered a predictable outcome. The inventory of man-made chemicals that continually feeds into the environment is alarming and, no doubt, contributes to a wide variety of diseases in both man and other species. However, ascertaining direct cause-effect relationships between a particular chemical or chemical complex and a host of diseases with endocrine manifestations in humans is, statistically, more akin to throwing darts than the beautiful abstraction of data practiced by Dr. Snow. The history of life, if we heed its lesson, says that species come and species go. Humanity's Day has spanned enough time for our speciallity, intelligence, to become our curse.
Intelligence takes the place of mutation in humans for adapting to environmental stress.
A fact that is not hypothesized, tested and replicated is still real. It doesn't await our awarness to exist. Set up your experiments, make your predictions, but, replicable or not, earth ecology has changed in human times. We are a dynamic, major drive toward a world in which we did not evolve. In the scheme of life, it doesn't matter.