Good web design loads fast and looks good. Yes it is possible. This is an especially big problem with larger websites. Identity is very important if you want your site to stick out in people's minds. The other problem with inconsistency is that it makes a site a lot harder to navigate.
Navigation is tricky enough without having to figure it out again on every page.
Sometimes we concentrate so hard on design, content, and usability that we neglect the little things like spelling, grammar, broken links. Unfortunately, your visitors will notice, and typos hurt your credibility a whole lot. Thankfully, all you need to do is proofread and check links. It's a good idea to have someone with fresh eyes check out your site as well. A little animation is okay, when used intelligently.