In difficult to treat patients, combination therapy may be beneficial. Treatment decisions are outlined in the table below. Condition Action Diabetes mellitus or gout Avoid niacin. Gemfibrozil or fenofibrate may be useful. Avoid niacin, statins, gemfibrozil and fenofibrate.
Drug therapy consists of gemfibrozil, fenofibrate, niacin, statins, or combination therapy.
Resin binding agents can increase triglycerides. At equipotent doses for LDL-C lowering, pravastatin, simvastatin, and atorvastatin decrease triglyceride levels to the same extent. Niacin or gemfibrozil raise HDL-C better than statins or resins. Post-menopausal women Consider hormone replacement therapy. Erythromycin, Azole antifungals, Cyclosporine, Niacin, Nefazodone - Statins Watch for myopathy or rhabdomyolysis.