Because of physical or chemical stress, antibodies denature in several applications or even during storage.
Recent results demonstrate that it also optimizes the function of antibodies during application.
Antibody is supplied as a lyophilized powder. Optimal results can be obtained with a final concentration between 0.1M and 1M. Typical concentrations are listed in the table. Typical Concentrations Antibody Stress factor Opt. 0.5M heating 1M freezing 1M Monoclonal antibody heating 0.5M Certificate of Analysis Reference Kaufmann, M., Galinski, E.A., Vangala, M.D., Schwarz, T., Stabilization of native antibody conformation by ectoines, Third Meeting on Extremophiles as Cell Factories, Techn. University of Graz, Graz, Austria, 3-6, June 1999.