The disease is caused when the spleen and lymph tissue produc antibodies against platelets. The antibodies destroy the platelets in the spleen, Skin hemorrhage, easy bruising, abnormal menstrual bleeding, or sudden and severe loss of blood from the gastrointestinal tract may occur. Usually, no other abnormal findings are present. In children, the disease is sometimes preceded by a viral infection and runs its course without treatment. There is no sex difference in children.
Risk factors are unknown.
The incidence is 1 out of 10,000 people. Physical examination reveals an enlarged spleen. In children, the disease often runs its course without treatment. All rights reserved.