The ratio of applications per place will help to dictate your general approach. You must specify in the offer if you want the grades or points excluding General Studies. It is essential that the University is open about its requirements and that offers conform, as far as possible, to those listed in the prospectus etc. The number of offers you make may seem a highly inexact science, but you will get a good idea of what to expect by looking at last years statistics. If low demand continues, try to find out the reasons for this.
Emphasis here is inevitably on rejection rather than acceptance.
Even with such demand, very high grades will put some applicants off. Such a course will almost certainly be well established, though there are examples of new, high profile courses that attract many applications. The expansion in recent years has led to a smaller percentage of applicants being interviewed and this trend is likely to continue as resources for interviewing will remain limited. It is important for departments to be clear about the purposes for which they hold interviews. Applicants for shortage areas in order to attract them to the institution and thus achieve difficult targets i.e. recruitment interviews.