As well as working against microbes, Nizoral also reduces the production rate of sebum. It has been suggested that androgenetic alopecia involves inflammation due to colonization of the hair canal by microbes as well as an increase in sebum production. Hair follicle sebaceous glands are androgen sensitive and in androgenetic alopecia the sebaceous glands become enlarged and produce more oils. More oils mean more sebum. This sebum, full of organic oils, is a rich source of food for skin flora and fauna.
Microbes are more likely to enter the hair canal and proliferate feeding on the sebum in the canal.
Nizoral may counteract these phenomena seen in androgenetic alopecia and some dermatologists believe this can help reduce hair loss and may help promote hair regrowth.