Good luck, and I'll be watching your progress. We don't want to use any more of your time. It's sad to think that Bill Gates, or Paul Allen, could finance a Mars Direct Mission out of their personal fortunes. Personally - No. I think that the cost high and the vision of the decisionmakers too limited.
Every skill needs a backup of some sort.
As for skills . . . Not just take care of themselves. So I think that you chuck the idea of a room full of Systems controllers monitoring the vehicle, first. Obviously, that wouldn't work in an interplanetary mission. You wouldn't want a comm outage to doom the mission.