The neuroAIDS section is conducting trials of agents which may be effective in treating several neurologic complications of this disorder. Current trials are looking at agent for the treatment of AIDS dementia complex , painful neuropathy and motor-cognitivedisorder. The overall goal of the study is to develop a reliable scheme to accurately assess the size and growth rate of plexiform neurofibromas in individuals with NF1 and to establish a body of normative data on growth rates. The investigators also intend to develop an international consortium of clinical centers for future therapeutic trials. In addition, Washington University will serve as the tumor tissue repository for this clinical trial.
Enrollment is now open.
The incidence of obstructive sleep apnea in patients with polycycstic ovary disease is being evaluated. The program currently offers intrathecal baclofen pump treatment for refractory spasticity. The program also offers inclusion in partial weight supported walking research , where paraplegic and tetraplegic patients are taught to walk on a treadmill, while being suspended and partially weight supported. These new treatments are designed to enhance cardiovascular function, improve muscle mass, reduce spasticity, and reduce medical complications. Recent experimental work also suggests that patterned exercise may enhance processes of regeneration such as new cell birth.