This is not gospel - what works for one person doesn't work for someone else, and we each form our own style. Please take these suggestions in that light.
Feedback is always welcome.
Decipher's site provides the rules for running such a beast, but not a lot in the way of helping you get organised - hence this article. It will attempt to cover staging the event, the event itself, and what to do afterwards. It cannot address every situation, but will hopefully guide you on your way to the first of a string of successful events. I find weekends are better because it fits players' schedules, but evenings may work well for your group. Do your homework - find out any possible conflicts that might crop up with other events.