Plus, there are new chemical methods for speeding solution phase purification. Trident works well for both solution phase and solid phase synthesis. Each reaction vessel is sealed tight and no septa are used for delivery. Teflon tubes fit tightly into these ports to accurately deliver solvents and reagents. In validation experiments , no cross-over contamination has been detected between vessels.
Experiments show that the delivery is reliable even with corrosive, volatile, and viscous reagents.
Variable agitation Set the agitation to the appropriate level for your reaction. The single axis oscillation adjusts from aggressive agitation to gentle mixing that will not degrade solid phase resins. Accurate, consistent temperature Temperature controlled air is continuously circulated around the open underside of the Reaction Cassettes to maintain temperatures between -40 to 150 deg C, with minimal temperature differences across all of the vessels of a Reaction Cassette. Liquid nitrogen is used for cooling. Variety of sample collection formats Collect samples in formats including test tubes, vials, and standard deep well collection plates and rotor blocks of commercial concentrators.