Approach your differences, in opinion or personality, as opportunities to find fresh solutions, ideas and perspectives. Your boss may avoid people because she knows she's hard to work with, but your positive attitude may quell her misgivings. Express reasoned opinions. Most companies still hold onto top-down management styles where employees subconsciously assume they must merely follow orders without any real sense of involvement. Respect and follow authority, but when asked your professional opinion, have one.
Managers appreciate employees who care enough about their work to stand up for what they believe in.
Commit yourself to continuous improvement. Streamline tasks, anticipate orders, and set an example. Any boss can relate to a healthy, overachieving employee who keeps the bottom line in sight. Have a clear picture of what you contribute, and verbalize it. Ask your boss how you can help her.