Studies on mechanisms, if they concur with the epidemiological evidence, increase the likelihood that the association is real. Far behind comes evidence from uncontrolled trials, case reports, and anecdotes. It is sobering that the best available evidence in this area, whether the subject be red wine, green tea, or antioxidants, comes from 'evidence of the third class' association, perhaps supplemented by pathophysiological, mechanistic considerations. The positive properties of red wine, green tea, and many fruits is widely considered to involve an antioxidant class of polyphenols, which in addition to their antioxidant properties have a range of pharmacological properties that could have health benefits. These benefits include a salutary action on platelets and blood vessels.
Endothelial dysfunction is characterises atherosclerosis, hypertension, and diabetes mellitus.
Although the evidence is still preliminary, it is worthwhile and constructive to consider the fact that the evidence suggesting a health benefit of cocoa and chocolate is at least comparable to the level of evidence supporting positive health effects of green tea and red wine. All Rights Reserved. We respect our visitors' privacy. Click here for a special note to parents.