Preliminary characterization of the some of the breast tumor cell lines described in these sections has resulted in the identification of the following cell lines whose special characteristics are described in some detail with illustrations when available. HCC1008were initiated from a primary carcinoma and an axillary lymph node, respectively, of the same patient. HCC1007 is partially adherent, and exhibits epithelial cell morphology.
Many cells also form vacuoles.
HCC1008 exhibits similar growth morphology, but appears to be more compact when compared to HCC1007. HCC1500 HCC1500 cells are small, epitheloid, and are tightly adherent. HCC1500 was initiated from a young woman with a significant family history of cancer. Her family included several patients with colon cancer, and another family member with breast cancer. Cell lines with Germline Mutations HCC1937 HCC1937 cells are large, finely vacuolated and epitheloid.