There are many subtle differences that might come into play when you go between families. Depends on your circuits. In my opinion, the major differences from the user's perspective, are speed , and input thresholds. Output drive capability. Output drive symmetry.
Faster gates make faster output edges.
Power dissipation, if you have a lot of them. You can get both. Some are OK with that, others aren't. Faster gates will see noise glitches on their inputs that slower gates miss. Get as many data books as you can and study them until you familiarize yourself with all these differences.