Through its Development Office, MCWT has operated many agricultural and capacity-building programs and projects throughout western Tanzania. The church is active in women's ministry, youth ministry, and prison ministry. Through its hospital at Sikonge and its dispensaries in numerous villages, MCWT brings a healing ministry to many people. Cross-cultural mission MCWT is actively evangelizing among the Sukuma people in the Lake Victoria region and among the Waha people in the border of Tanzania and Burundi along the shores of Lake Tanganyika. The church has planted 16 congregations among the Sukuma people in the past 12 years.
Evangelism is effected through open-air meetings led by teams of evangelists and church choirs.
Persons responding in faith to the gospel receive ministries of counsel, deliverance and instruction, leading to baptism. Leadership and government Bishop Isaac R. Nicodemo is the chairman of the provincial board of the Moravian Church in Western Tanzania. The office of vice-chairman is currently vacant. A provincial board drawn from a wide geographical area meets four times per year and is the church's leadership authority between synods, which are held every three years. Within the worldwide Moravian Unity, MCWT is fully self-governing.