AFP can be measured in amniotic fluid as a diagnostic test for neural tube defect and other open fetal defects. Maternal weight, race, and other factors are taken into account, and must be provided. An interpretive report is provided. MS-AFP is not diagnostic in itself, but can indicate when other tests are needed. Interpretive reports are available for specimens drawn from week 11 through week 25, for which comparative data are available.
Elevated levels suggest neural tube defects or abdominal wall defects and AChE is indicated.
AChE is also indicated in all cases at week 22-25, and is done automatically at additional charge. An interpretation for Down Syndrome risk is not provided from AF-AFP levels and is not needed, since direct chromosome analysis is definitive. Label with name and draw date. Normal results are reported in 2-3 days. Do not centrifuge.