Electron microscopy is necessary to distinguish the two conditions. Wavy filaments are absent in amyloid. No treatment is available that is entirely satisfactory. Dermabrasion, cryotherapy, and diathermy have been tried with limited success. Lesions remain static and do not resolve.
Genetic counseling is advisable for the rare juvenile form.
Sun avoidance seems sensible, but no evidence is shown that this intervention helps. Juvenile colloid milium. Exogenous ochronosis and pigmented colloid milium from hydroquinone bleaching creams. Juvenile colloid milium. Colloid milium and nodular colloid degeneration.