Our basic tactic is to isolate genetic mutants affecting the synapse, characterize the synaptic phenotypes of these mutants, and identify the genetic and molecular structure of these synaptic components. This work requires geneticists, molecular biologists, developmental cell biologists, morphologists, and electrophysiologists. If the brain holds a fascination for you, and if you are intrigued by any of these disciplines, I encourage you to come lend a hand. Development of the embryonic neuromuscular synapse of Drosophila melanogaster. Broadie, K. and M. Bate. 1993.
Innervation directs receptor synthesis and localization.
Broadie, K. 1994. Broadie, K. 1996. Regulation of the synaptic vesicle cycle in Drosophila. Prokop, A., M. Landgraf, E. Rushton, K. Broadie and M. Bate. Baumgartner, S., T. Littleton, K. Broadie, R. Harbecke, J. Lengyel, A. Prokop and H. Bellen. 1996.