Migraine headaches have been associated with estrogen therapy, although this reaction occurs infrequently. Thromboembolism and thrombus formation are occasional, serious adverse reactions to estrogen therapy. A positive association has been noted between dosage and thrombotic disorders. In addition, cigarette smokers are at a higher risk. Patients requiring estrogen therapy should be strongly encouraged to discontinue smoking.
Estrogens can cause sodium and fluid retention.
They should be prescribed cautiously to patients in whom edema formation would be detrimental. In addition, estrogens also can slightly increase blood pressure, occasionally causing hypertension. Estrogens are essential for maintaining normal female functions, such as ovulation, menstruation, pregnancy to term, and normal female development. Generic conjugated estrogen tablets are not yet available. Take conjugated estrogen tablets by mouth.