There are several important clinical consequences of these changes.
Impaired digestion is due to the loss of peptic activity.
Loss of appetite is often significant and seems to be related to the level of infection. However, the physiological explanations are still somewhat obscure. One explanation is based on the knowledge that g.i. It has also been suggested that pain may be an important cause of inappetence but this is difficult to assess. Diarrhea has been reported in all the important g.i. nematodes, except Haemonchus.