Heterologous protection against influenza by injection of DNA encoding a viral protein. Accell particle-mediated DNA immunization elicits humoral, cytotoxic, and protective immune responses. Fynan, E.F., Webster, R.G., Fuller, D.H. et al. Protective immunizations by parental, mucosal, and gene-gun inoculations. The use of microparticle injection to introduce genes into animal cells in vitro and in vivo.
Genetic immunization is a simple method for eliciting an immune response.
Introduction of foreign genes into tissues of living mice by DNA-coated microprojectiles. In vivo and in vitro gene transfer to mammalian somatic cells by particle bombardment. Immunization with plasmid DNA using a pneumatic gun. Raz, E., Carson, D.A., Parker, S.E., Parr, T.B., Abai, A.M., Aichinger, G., Gromkowski, S.H., Singh, M., Lew D., Yankauckas, M.A. et al. Martinon, F., Krishnan, S., Lenzen, G. et al.