Sorbitol is implicated in the development of diabetic complications including cataracts, neuropathy and retinopathy. Studies show decreased cataract formation in the lens of diabetic animals. Its potential influence on diabetes may also relate to enhanced insulin secretion, protection of pancreatic beta cells from free-radical damage, and inhibition of platelet aggregation. Quercitin has anti-viral action against a number of different viruses, and inhibits a number of different cancers in experimental models. Inhibition of human lens aldose reductase by flavonoids, sulindac and indomethacin.
Experimental studies suggest potential benefit in arteriosclerosis, heart disease and stroke.
No side effects or significant drug interactions have been reported. They have a broad range of pharmacologic activity through increasing vitamin C levels, decreasing capillary permeability and fragility, scavenging free radicals and inhibiting destruction of collagen. E. These influences, along with other mechanisms, explain there benefit in venous and capillary disorders, including venous insufficiency, capillary fragility, diabetic retinopathy and macular degeneration. Studies show that PCO also lowers cholesterol levels and can shrink arterial cholesterol deposits. 4,729 patients undergoing hormonal and pro-cyanidol oligomer therapy.