Adjuvant interferon- alfa appears to confer survival benefits in patients with regional nodal disease. Effective salvage therapy has not yet been identified. Two cases of benign vaginal rhabdomyoma, which occurred in women aged 38 and 54 years, are reported. The macroscopic and microscopic appearance is described. The literature on this rare tumour is reviewed and the differential diagnoses are discussed.
Local excision is considered adequate treatment.
Schneider HP TI - Malignant melanoma of the vulva. Report of 89 patients. Rates of melanoma have increased worldwide over the last few decades. Due to the rarity of this disease, treatment recommendati- ons do not exist. This retrospective study was designed to evaluate the significance of clinical and pathologic features for survival among 89 patients examined for malignant melanoma at 5 hospitals in Germany from 1978 to 1991.