The best drug references just got better. Use only in pregnancy if the potential benefit to the mother outweighs the potential risk to the fetus. Patients with signs or symptoms of pancreatitis should be evaluated and therapy suspended as clinically appropriate. Diabetes mellitus and exacerbation of diabetes mellitus have been reported in patients taking protease inhibitors.
Hemophilia type A and type B have been reported with protease inhibitor use.
Redistribution or accumulation of body fat has been observed in patients using antiretroviral therapy. The potential for cross-resistance with other protease inhibitors is currently under study. Treatment should be symptomatic and supportive. Activated charcoal may aid in the removal of unabsorbed medication. Avoid exposure to excessive heat.