Using this route, we have made about 100 known and new camptothecin analogs, and some of the new ones are excellent pre-clinical candidates for the treatment of refractory solid tumors. Click here for more information. In addition to developing new classes of cascade radical reactions directed towards other natural products, our work in the radical field focuses on new methods of stereoselection. We have shown for the first time that it is possible to achieve stereoselection, solely by orchestrating reaction pathways and without any traditional stereoselective step such as a face or group selective reaction. In another project, we use traditional strategies for stereocontrol, but implement these with new classes of molecules like axially chiral amides .
Fluorous reactions are highly suited for combinatorial chemistry and parallel synthesis.
Click here for more information. Graduate Admissions - Important material for prospective students. All the reasons why you want to move to Pittsburgh.