Well, so far so good. Obviously despoiling the earth is the current overriding matter of concern. It's now agreed all around in the biological community that symbiosis is the rule rather than the freak exception. The interdependence of organisms is quite spectacular. The earth itself behaves a lot like an organism.
Human beings have to bring their behavior in line with the inherent symbiosis of all living things.
Also I think the invention of the nation state, which is really historically a recent phenomenon, is obviously a great danger for the earth itself. Nationalism, war departments relabeled defense departments . . . It's a risky way to live for the planet, but I haven't a ghost of an idea what a better way would be. Yet I suspect in my moments of optimism that we'll learn something new and different and begin reducing the risk. People seem to actually like to fight sometimes.