People with the disorder are not normally anemic and display no evidence of the disease until the red cells are exposed to an oxidant or stress . The risk of acute hemolytic crisis can be decreased by reviewing the family history for any evidence of hemolytic anemias or spherocytosis or testing before giving any medications belonging to the above class of chemicals. Risk factors are being of the black race, being male, or having a family history of G6PD deficiency. Another type of this disorder can occur in whites who originated in the Mediterranean basin. It, too, is associated with acute episodes of hemolysis.
Episodes are longer and more severe than the other type of disorders.
If the cause is an infection, it should be treated, or if the cause is a drug, the offending agent should be stopped. People with the Mediterranean form or those in hemolytic crisis may occasionally require transfusions. Spontaneous recovery from hemolytic crises are the normal outcome. Complications Rarely, death may occur following a severe hemolytic event. Calling Your Health Care Provider Call for an appointment with your health care provider if symptoms of hemolytic anemia due to G6PD deficiency develop.