The pregnancies are at higher risk of spontaneous abortion, premature labor, pseudo-toxemia and cesarean section. The fetuses are more likely to have growth lags, and more trouble with the stresses of labor and delivery. After the birth, all women are more likely to have infections and blood clots, but the risk for sickle cell mothers is even greater. But don't worry too much. Pregnant women with sickle cell are almost always anemic at the first pre-natal visit.
Folic acid is given routinely.
This is just the same as in non-sickle cell pregnancies, it is simply more important in sickle cell pregnancies. The norm of giving iron supplements to pregnant women should not be followed without lab testing to show that is indicated. Sickle cell patients may be overloaded with iron because of frequent past transfusions. Morning sickness poses extra risks for women with sickle cell. Morning sickness can lead to dehydration and dehydration causes sickle cell crisis.