Aneuploidy for the X chromosome is often not lethal to the individual because of X-inactivation. Dosage compensation results in equalizing the level of expression of many genes on the X chromosome in both sexes, even though males and females have a different complement of sex chromosomes. The phenotypic consequences of chromosome mutations depends on the type of rearrangement and how extensive it is. Chromosome mutations that are heterozygous will frequently have meiotic pairing problems in meiosis I. This can lead to gametes that are unable to generate viable zygotes upon fertilization by a normal gamete. In cats, there is a gene which controls coat color which is located on the X chromosome.
Males can be either black or orange.
In a litter of newborn kittens, you observe three orange females, one orange male, two black males and five calico females. Using the appropriate symbols, show your reasoning.