They can be easily trained to use a litter box because they tend to habitually urinate and defecate n the same places. Provide a low-sided litter box for easy entry and exit. More than one litter box may be necessary if the ferret has free run of the house. There is no innate animosity between ferrets and dogs and cats, and all can usually share a household with little difficulty. However, ferrets have been known to attack pet birds, so it is advisable for owners of both to take appropriate precautions to prevent these encounters.
Ferrets are naturally inquisitive and can squeeze through very small spaces.
Thoroughly check every room it will inhabit, sealing all holes and openings wider that 1 inch in diameter. Make sure that all windows that may be opened have secure screens. Check the openings around plumbing, heating, and air conditioning ducts or pipes. Some kits are small enough to squeeze under some doors. Ferrets are so small and silent that you will usually not hear them approach.