Discard the packaging in the garbage. Remove the red tape from the bottom of the gel. Carefully grasp the loop on the comb and gently pull it straight out. Slide the gel sandwich into the plastic block, with the lower plate facing out and the larger plate against the plastic. Stand up the unit and ensure that the gel is straight and level in the block.
Finger tighten the four screws.
Place the block on the central electrode unit, ensuring that it is tightly and correctly inserted. Place another gel on the other side of the electrode unit. Place the central electrode unit in a chamber, and fill the inside unit with 1X Tris-Glycine Running Buffer to above the level of the inner plate. Examine the unit for leaks. If extensive leaking is noted, pour out the buffer and reattach the gel blocks.