Coated-particle aggregates form rapidly in pressure nodal regions. Examination, subsequent to removal from the USSW, shows clear analyte-induced aggregation down to low antigen concentrations. Detection of polysaccharide and protein antigens of bacterial, viral, or mammalian origin has been enhanced from 16 to 2,000 fold compared to standard LAT sensitivities. Meningococcal antigen detection Particular attention has been paid here, in collaborative work with clinical laboratories, to USSW detection of meningococcal antigens. Meningitis and meningococcal septicaemia develop extremely rapidly.
LATS are among the rapid techniques for detecting menigococcal antigen but lack sensitivity.
The order of 32 fold enhancement of antigen detection in the USSW system extends analytical capability to cover the antigen levels in the serum from most presenting patients. The USSW technique is specific, simple and rapid. Serogroup results with both methods were concordant. A force field ultrasonic filter for analytical environmental sample clarification. Environmental water samples, and analytical samples in a more general way, can benefit from the presence of an on-line particle prefilter e.g. when analysis is based on optical techniques.