Unfortunately, inhibitors in people with hemophilia B can be extremely serious because they can be accompanied by allergic reactions. No, inhibitors come in different degrees of severity. They work much more slowly to eliminate the infused factor concentrate. Their inhibitors are present at high levels and respond very quickly to the infusion of factor concentrates. As a result, the factor concentrates infused can be rapidly neutralized.
Inhibitors can vary in severity in the same person.
Doctors do not know exactly why inhibitors develop in some hemophiliacs and not in others. They think there are 2 possible causes. The first possible cause is environmental. This is external to the hemophiliac. Doctors think that something in the factor concentrate triggers the body s immune system to react.