The Teays did not reform after the ice melted. New River of western North Carolina was a tributary of the Teays and is the second oldest river of the World. Asians came to America about 20,000 years ago via the Bering Straits land bridge during the ice ages when so much water was locked up in ice that the oceans levels were lowered. When the Vikings came to America via Iceland and Greenland, the native American were able to destroy their small settlements. Before Europeans came in force, more or less constant warring tribes in America destroyed the agricultural civilizations that sprang up.
Geology determines the location of game trails.
For 15,000 years Indian trails followed the game trails. Early pioneers followed the Indian trails. Some Indian trails ran hundreds of miles. I-64 follows or parallels a Buffalo trace. Palmyra is on that original Buffalo Trace, Indiana's first road.