All drugs continued entire time even if no INH resistance. INH may be discontinued. Appropriate Blood Tests Symptom Review Compliance Assessment. Reassess treatment regimen if the smear or culture is still positive at 3 months. MDR TB requires careful assessment and individual tailoring of treatment regimen.
Expert consultation is required.
Special drug request forms must be approved by TB Control before these drugs can be dispensed. The most effective treatment regimen possible should be used. Co-infection with TB and HIV is an absolute indication for Directly Observed Therapy. However, the use of Rifampin with protease inhibitors or non-nucleoside reverse transcriptase inhibitors is contraindicated. Rifabutin may be substituted for Rifampin in drug sensitive patients in certain situations.