This fluid is needed because it allows nutrients to be available in the cartilage and acts as a shock absorber. Chrondroitin is needed to keep healthy cartilage from breaking down and stimulates the production of proteoglycans and collagen, cartilage matrix molecules that serve as building blocks for new cartilage. It also inhibits destructive enzymes that prevent the transport of nutrients. It is necessary for the production of Chrondroitin, a substance found to be abnormally low in individuals with arthritis. Glucosamine encourages production of collagen, the fibrous protein substance that holds joints together.
Glucosamine helps bind water in the cartilage matrix, and is key to normal cartilage metabolism.
Of all natural nutritional substances advocated as beneficial and important for joint functioning, never have we seen a substance demonstrate such important and significant clinical effects as researchers have seen with glucosamine sulfate. Glucosamine sulfate is almost devoid of toxicity, and is suitable for long-term use. These and other safe nutritional measures supporting proteoglycan synthesis, may offer a practical means of preventing or postponing the onset of osteoarthritis in older people or athletes. The body uses MSM to continually create new healthy cells to replace old ones. The body used vitamins and amino acids with MSM in this process.