Frequent urination, headaches, or urinary tract infections. Low back or flank pain. Cysts in the liver and pancreas are frequent, but usually not troublesome. Kidney enlargement is very common. Diverticulosis of the colon is common.
Hiatal hernias are frequent.
Intense pain in upper abdomen or flank. When PKD becomes advanced, the numerous cysts that are growing throughout the kidney have grown to a point where they are crowding out much of the functioning normal kidney tissue. When this occurs, the normal waste filtering functions of the kidney become impaired and eventually non-existent. At this stage of PKD, the functioning of the kidney resembles the functioning of kidneys from many kidney diseases. PKD is a genetically passed disease .