A symptom of DEET toxicity is increase in blood pressure. Lead causes peripheral neural demyelination. Children are more likely to take in toxicants through the skin than adults are. Type 1 reaction is not IgE mediated. You will most likely experience an allergic reaction on your first exposure to an allergen.
Environmental conditions add to the irritation of a toxicant.
Skin injury enhances toxicant absorption. Lead poisoning is treated with Desferal. Treatment of choice for a metal poisoning is inactivation with a chelator. Calcium disodium EDTA is a food preservative used in the treatment of lead poisoning, but it does not pull lead out of bones. Desferal binds free iron, heme, and other important minerals.