The problem with shinkansen travel in Japan is that it is very expensive, especially for foreigners. Before using your pass, you must validate it at a major JR station. Using the rail pass and the JR network is a snap. English signs in all stations direct you to the shinkansen platforms, which will be on their own in a special part of the station. Announcements and digital displays in-carriage indicate the next stop.
English timetables are available from information counters at the station.
Making a reservation can be a lengthy procedure if the ticket office at your station has no English speaker. The easiest way to make a reservation, is to come prepared. Get a piece of paper, and scrawl your destination in Romanji along with the time you want and a non-smoking symbol. Present this with your pass to the reservations counter and the transaction will be a breeze. Having said this, most major shinkansen stations will have already equipped its staff with the English required to service foreign travellers.