Other differentials should include Salmonellosis, Campylobacteriosis, E. coli infection, coronavirus infection, canine distemper or other enteric viruses. However, if the test is negative and parvo is highly suspected, wait 48 hours and run the test again. The virus is not shed until after day 3 and so it may be too early to test the feces. Conclusive proof of CPV infection, however, is made with electron microscopy. First stop all food and water intake if the patient is still vomiting.
Fluid therapy is very important.
The easiest way to do this is to estimate the volume of the loss, then double it and give the animal a fluid bolus of that amount. Secondly, a broad-spectrum antibiotic should be given. Antiemetics may be necessary. If albumin is low or total solids are dropping, a plasma transfusion or hetastarch can be given. Monitor body weight to make sure it is not decreasing.