Today, a global network of researchers announced that they are collaborating in sequencing the genome of Anopheles gambiae , the mosquito responsible for most cases of malaria in Africa. This information, together with the knowledge gained from the sequences of malaria parasites and the human genome, will provide researchers with a wealth of genomic data necessary for understanding this complex disease. The need for a multifaceted commitment to fight malaria and develop new and improved treatments, diagnostics and vaccines has never been greater. Malaria is a public health threat in more than 90 countries, where 40 percent of the world's population lives.
Malaria is caused by a single-celled parasite that is spread to humans by mosquitoes.
The control of malaria continues to be a challenge because of the dual problems of increased rates of insecticide resistance in mosquitoes and increased rates of drug resistance in the malaria parasites. Reducing disease transmission by mosquito control has been a mainstay of regional and global malaria control programs. The insecticide DDT was once a powerful tool in global efforts to eradicate malaria. With the development of DDT-resistant mosquitoes, new tools are needed to control this disease. An improved understanding of the basic biology of mosquitoes and their genomes will contribute to our ability to understand and monitor insecticide resistance, develop new insecticides, and ultimately help control the malaria pandemic.