Prostate cancer is the most commonly occurring tumor in U.S. men. Differences in the incidence of this disease among ethnic populations are not due solely to genetic differences. Many efforts have been devoted to studying associations between nutrition and prostate cancer. The strongest association appears to be related to total fat intake and increased risk of this malignancy. Evidence also exists to suggest a role for certain micronutrients, such as zinc, selenium, vitamin E, lycopene, phytoestrogens, and phytosterols, although the role of nutrition and micronutrients in protection against prostate cancer is less convincing.
Further research is necessary.
A structured questionnaire was used to obtain a history of long-term exposure to arsenic through consuming artesian well water and fasting serum samples were also collected at the recruitment. There was a significant biological gradient between the risk of ISHD and the duration of consuming high-arsenic artesian well water. Multivariate analysis showed a synergistic interaction on arsenic-related ISHD between duration of consuming artesian well water and low serum carotene level. An increased risk of arsenic-related ISHD was also associated with hypertension and elevated body mass index, but not with serum lipid profile, cigarette smoking and alcohol drinking. Schmidt R, Hayn M, Reinhart B, Roob G, Schmidt H, Schumacher M, Watzinger N, Launer LJ Department of Neurology, Karl-Franzens University Graz, Austria.