This Publication Is Searchable The Merck Manual of Diagnosis and Therapy Section 17. Genitourinary Disorders Chapter 227.
Etiology is unknown.
The bladder wall shows inflammatory infiltration with mucosal ulceration and scarring that results in smooth muscle contraction, diminished urinary capacity, hematuria, and frequent, painful urination. Carcinoma in situ can mimic IC and must be ruled out. Bladder distension may provide excellent, but transient, relief. Rarely, augmentation cystoplasty may be undertaken. Very rarely, cystectomy with urinary diversion is required.