Entrepreneurs thrive on risk. It's a different attitude toward failure and another culture conflict to explore. Time Commitments - Large companies make a clear distinction between work and leisure hours. Entrepreneurs merge their business and personal time. Employees - Large companies crave large numbers of employees to build power structures.
Entrepreneurs run lean employee machines to contain overhead.
Compensation - Large companies pay big salaries. With all the industry consolidation and continuing downsizing going on in the large corporate environments, there are some subtle considerations for you to note. These fall under entrepreneurial due diligence requirements. Some can be accomplished prior to approaching a prospective alliance partner. Clearly identify market or industry area leaders - Maybe your assessment will show that you are better off teaming up with a second or third tier company.