Please conduct a current literature search and check the appropriate current online database for the most recent quantitative information. Animal studies have reported effects on the blood, liver, and kidneys from chronic inhalation exposure to ethylbenzene. No information is available on the developmental or reproductive effects of ethylbenzene in humans, while animal studies have reported developmental effects, including birth defects in animals exposed via inhalation.
Limited information is available on the carcinogenic effects of ethylbenzene in humans or animals.
EPA has classified ethylbenzene as a Group D, not classifiable as to human carcinogenicity . Exceedance of the RfC does not imply that an adverse health effect would necessarily occur. As the amount and frequency of exposures exceeding the RfC increase, the probability of adverse health effects also increases. The average level in suburban air is about 0.62 ppb, while the average level measured in air in the country is about 0.01 ppb. In a 20-year study of humans occupationally exposed to ethylbenzene, no liver toxicity was noted.