Efficacy of enzyme supplementation after surgery for chronic pancreatitis. 13Carbon mixed triglyceride breath test and pancreatic enzyme supplementation in cystic fibrosis.
Intraduodenal proteases exert a negative feedback on pancreatic secretion.
Twenty healthy males were studied on two different days one week apart. After an overnight fast a nine-lumen motility tube was positioned with the distal tip at the Treitz angle. Secretion of human-specific pancreatic elastase and bile acids was measured by a standard duodenal intubation perfusion technique. Plasma concentrations of gastrin and pancreatic polypeptide were measured by specific radioimmunoassays. No changes were observed in bile acid secretion, antroduodenal motility or release of gastrin and pancreatic polypeptide.