Of the three main types of toxins identified above that lead to fibromyalgia, the metabolic toxins are the least important in the initial stages, but the most dangerous in advanced stages of fibromyalgia. The reason for that is that all kinds of metabolic havoc are wreaked on the human tissues once oxygen metabolism becomes dysfunctional. The full significance of that statement becomes obvious in the chapters devoted to oxygen metabolism later in this volume. In health, the detox mechanisms of the body neutralize and clear such oxidants. In illness, such oxidants are produced in such large quantities that the detox systems fail.
Excess oxidants accumulate and cause oxidosis which, in turn, leads to dysoxygenosis and acidosis.
The states of illness that lead to oxidosis and dysoxygenosis include fibromyalgia, chronic fatigue syndrome, chemical sensitivity syndrome, and others. Microbial oxidants are produced in large quantities by microbes which live in the body in health. Those microbes multiply rapidly in the bowel and blood ecosystems with sugar overload, antibiotic abuse, pesticides, pollutants, and other toxins. All microbial oxidants cause oxidosis which, in turn, leads to dysoxygenosis and acidosis. The toxic burden of chemicals has increased markedly during this century.