These are large ovoid cells with basophilic cytoplasm . Eosinophils increase in tissue in response to both allergy and parasites. Chemotactic factors released in inflammation attract more eosinophils. These cells also help brake the inflammatory reaction. Secreted arylsulfatase and histaminase destroy leukotriene and histamine mediators of inflammatory reaction.
Eosinophils can also phagocytose and digest antigen-antibody complexes .
This connective tissue is flexible, well vascularized, and has little tensile strength. It appears as a loose, irregular network of fibers and cells with abundant ground substance . The ground substance is not preserved in routine histological preparation, resulting in an empty appearance with scattered cells in section. Dense connective tissue has relatively abundant collagen fibers , less ground substance, and even fewer cells, mostly fibroblasts. Dense connective tissue can be sub-classified into regular and irregular types.