During liver disease, any copper supplementation may lead to toxicity. Copper is excreted via the liver and can build up if liver function is impaired. In fact, those suffering from Wilson's disease , a hereditary disorder of the liver that causes the liver to store excess copper, should avoid copper. Iron Toxicities are most common in children who take doses meant for adult supplements. Toxicity can also more easily occur in persons with idiopathic hemochromotosis , a genetic disorder that enhances iron absorption.
Iron toxicity can result in multiple organ failure and death.
Manganese During liver disease, a ny manganese supplementation may lead to toxicity. Manganese is excreted via the liver and can build up if the liver function is impaired. Selenium Too much selenium can result in nausea, abdominal pain, diarrhea, and fatigue, to name a few. The amount that causes toxicity is not clearly defined. However, doses of 5 mg or more per day have been shown to cause symptoms.