Each board is comprised of researchers who periodically review data from blinded, placebo-controlled trials. The researchers should be independent of the trials they're monitoring. A DSMB board has the authority to stop a trial if the toxicities are found or if the treatment is proved beneficial. These boards are also known as Independent Data-Monitoring Committee.
Every clinical trial has a beginning a middle and an end.
Part of the end process is the submission of certain patient data regarding the safety and effectiveness of the drug during the clinical trial. This date and time is called Data Lock. See also Clinical Trials . A widely used method of data encryption using a private key that the U.S. government judged so difficult to break that it was restricted for export to other countries. Each message uses one of 72 quadrillion or more possible encryption keys that are chosen at random.