Newer class of beta-cell stimulator, more rapidly absorbed and cleared from blood than sulfonylureas. Can be used to help manage blood sugar changes after specific meals. Biguanides Metformin Glucophage Increases insulin sensitivity of liver cells, thus reducing liver cell production of sugar. Liver cells add sugar to the blood when not adequately stimulated by insulin. Not advised to those who drink alcohol heavily, or those with kidney problems Alpha-glucosidase Inhibitors Acarbose Precose Reduces digestion of starch into sugar in the intestines.
Less sugar is absorbed into the blood after meals.
May cause digestive tract side effects. Increases insulin uptake from blood into target cells. Makes insulin more effective and less is required.