The ATL also provides analytical services to the faculty of the Georgia State University System on a cost recovery or collaborative, basis and is used in the support of federal and private grant applications. For example, the ATL currently provides analytical and neurochemical services in support of an inter-institutional collaborative Department of Defense Grant designed to study the nature of cognitive deficits suffered by returning Gulf War Veterans. This facility is used for the biochemical analysis of tissue sections fixed or frozen on glass slides. One of these is a sledge microtome for cutting large sections. The facility supports methods in standard tissue staining, immunohistochemistry and quantitative autoradiography.
Images can then be pseudo-color enhanced for ease of presentation.
Estimation of plasma scopolamine-like activity by radioreceptor assay in patients treated with a new antihistamine compound. Estimation of the release of brain acetylcholine and biogenic amines in microdialysates from freely moving rats by HPLC and electrochemical detection. Demonstration of amyloid senile plaques in the brains of aged monkeys by immunohistochemistry. Measurement of brain nicotine binding sites by quantitative receptor autoradiography.