Inhibits platelet aggregation in all species. It is present to enhance the dissolution rate and hence the absorption rate of the aspirin. Aspirin with Maalox - Antacid component does alter gastric pH. Whether this is important to protect the GI tract is unclear. Additionally, the enteric coating makes aspirin absorption erratic and unpredicable. Less frequent dosing is suggested.
Fetus is at some risk if mare is receiving phenylbutazone as it does cross the placenta.
Mostly in horses, though there are plenty of anecdotes about dogs and cats. Dosing is not confirmed for this indication. Efficacy against endotoxemia has been confirmed but the dosing has not been optimized. Ketoprofen Clinical Uses Dominant use is as a substitute for flunixin . Evidence of lipoxygenase inhibition is sketchy and has basically been discounted.