In cardiogenic shock , the preload and the afterload are increased, while myocardial contractility is decreased. Some examples of ischemic heart disease include Kawasaki disease, anoxic injury and anomalous injury of the left coronary artery. Chronic drug toxicities include toxicities to chemotherapeutic agents and to radiation. The infiltrative diseases include mucopolysaccharidoses, and the glycogen storage diseases. The second type of shock is hypovolemic shock.
Hypovolemic shock is caused by a reduction in the volume of blood.
Volume depletion is usually caused by vomiting, diarrhea, diuretic over usage or ketoacidosis. Hypovolemic shock can also be found in cases of internal sequestration such as ascites, pancreatitis and intestinal obstruction. Hypovolemic shock can also be found in patients suffering from severe burns, who are at high risk for losing large amounts of plasma. In hypovolemic shock, preload is decreased, afterload is increased, and the myocardial contractility remains normal. The third type of shock is septic shock.