We are Beacons of Light for Each Other. Our Bookstore x x Skin Involvement General Concept Scleroderma is a disease of the connective tissue disease. The characteristics usually involve excessive fibrosis.
Fibrosis is a result of the natural reparative process.
Our bodies just seem to overproduce collagen. Therefore, excessive skin thickening occurs. The actual cause is still unknown. Most people that are going to have extreme skin involvement experience this early on in their disease. Usually the first complaints are with puffiness and swelling of the hands.