Weedon D. Weedon's Skin Pathology. Churchill Livingstone. 1997. In the largest vessels, there is a smaller network of vessels called the vasa vasorum, that allow oxygen rich blood to perfuse the vascular wall. Elastic lamina -These are layers of elastic fibers which provide elasticity to the vessel wall. There are two layers, an internal elastic lamina just below the intima, and an external elastic lamina, sandwiched between the adventitia and media.
Endothelial cells -These cells form the lining of the blood vessels.
They are a dynamic part of blood vessel maintaining the permeability, helping to regulate inflammation, and playing a critical role in blood coagulation and clotting. Intima -This is the inner lining of the blood vessel formed by the endothelial cells and a small amount of connective tissue. Media -This is the layer of smooth muscle and elastic fibers which provide much of the strength and elasticity of the vessel.