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The blastpgp program can do an iterative search in which sequences found in one round of searching are used to build a score model for the next round of searching. Traditionally, it has been implemented using an AxA substitution matrix where A is the alphabet size. To skip quickly from the output of one round to the next, search for the string 'producing', which is part of the header for each round and likely does not appear elsewhere in the output. Both 'dust' and 'seg' are integral parts of the NCBI toolkit and are accessed automatically. This options also takes a string as an argument.