Using cells grown in a way that mimics the natural conditions of the lung, Meetpaul applied electrical and chemical methods to understand how the molecule that is lost in cystic fibrosis normally interacts with other molecules in the cells. Among his many findings, Meetpaul has proved that in this cell type, the cystic fibrosis molecule is essential for proper functioning of the glands, and no other molecule appears capable of taking its place. The skill and dedication Meetpaul brings to this project, his curiosity, and his tenacity are commensurate with graduate student work. Stanley Falkow, Department of Microbiology and Immunology Tuberculosis is still one of the leading causes of death in the world. In recent years, this disease has become even more terrifying because the causative microbe, Mycobacterium tuberculosis has become resistant to current antimicrobial therapy.
M. tuberculosis is difficult to grow in the laboratory and requires special precautions.
Hien Tran's research has focused on a microbe closely related to M. tuberculosis. This organism called Mycobacterium marinum causes disease in fish and amphibians as well as skin infections . Using M. marinum, Hien has worked out genetic and molecular methods that can be applied to the study of the tubercle bacillus. Hien's work has received considerable attention. He received a fellowship from the American Society for Microbiology to support his work.