Above all the government should see its role as protecting health, not profits. All that would require a starting presumption exactly backward from the one that now prevails. While resolving scientific doubt, don't keep exposing the public to risk. People are more important than companies. Nature is more important than the stock market.
Life is more important than power.
Serious campaign reform, getting private money out of public business, is the only way I can see that we can ever have a government we trust.