Bridge to liver transplantation. 1997 Impact of continuous hemofiltration on cytokines and cytokine inhibitors in oliguric patients suffering from systemic inflammatory response syndrome. Continuous hemofiltration has been applied to a variety of clinical situations, from fluid overload to hypothermia to intoxication. Since their survey in 1991, however, practice patterns have probably changed. CVVH has been applied in a number of intoxications, such as with ethylene glycol .
Filtration can be effective in traumatic rhabdomyolosis as well.
Its perioperative use is increasing, perhaps more than in the medical spheres. There is abundant evidence that several of the inflammatory mediators responsible for SIRS, and eventually for multiple organ failure, are filtered by the membrane. However, it remains to be seen if filtration can proceed at a rate sufficient to attenuate the disease process and decrease mortality. This remains unanswered in the clinical setting. The procedure has been shown to be safe .