Microfractures in the tibia or femur may be seen. Serum calcium and phosphorus levels usually are normal, but serum calcium may increase during bed rest. Radionuclide bone scans using technetium-labeled phosphonates show increased nuclide localization to the pagetic sites and can be a useful screen for extent of disease. Treatment Localized, asymptomatic disease requires no treatment. Orthotics help correct abnormal gait caused by bowed lower extremities.
Drug therapy influences mineral ion fluxes and suppresses bone cell activity.
Calcitonin may also be given as a nasal spray in patients who have received no pain therapy. All rights reserved.