The goal of Human Genome Project is not only to determine the sequence of the 3 billion nucleotides of the human genome, but also to understand the role that each gene plays in the entire life span of the human being.
Genome research differs from basic biology research in the enormous number of samples processed.
Developing new technologies and approaches to handle the large number of repetitive tasks has been a constant challenge for researchers in this field. The outpouring of sequence and associated biological information will soon change the way biologists conduct research. Effectively using the information generated from the genome project is an another challenge ahead of us. The main focus of my laboratory has been to develop and utilize clone based maps to explore genes in several biologically important regions. The first region spans approximately 4 Mb of DNA on chromosome 21q22.2.