This described several adverse reactions to the drug in a very short time span at a veterinary teaching hospital. All the adverse reactions were in Boxers. The announcement suggested that Acepromazine should not be used in dogs of the Boxer breed because of a breed related sensitivity to the drug. This drug is the most commonly prescribed tranquilizer in veterinary medicine. It is also used orally and is prescribed for owners who want to tranquilize their dogs for air or car travel.
Every vet has one.
Giant breeds, as well as greyhounds, appear quite sensitive to the clinical effects of the drug, yet terrier breeds appear more resistant. Boxer dogs, on the other hand, are predisposed to hypotensive and bradycardic effects of the drug. This should be enough of a warning for your vet.