Theoretically, the drug is carried to the site of inflammation on albumin. Higher doses are more analgesic but can only be used for short durations. Higher doses are more analgesic but can only be used for short durations. Carprofen and etodolac appear to be the safest. Coagulation - a desirable effect in some situations but can be a problem.
Effect is marked even at low doses.
This effect with carprofen should not have been a surprise. Blood dyscrasia - phenylbutazone. In the dog, aspirin has largely been replaced by carprofen and etodolac. It is still a useful drug however, and should be considered when carprofen and etodolac are too expensive. It must still be dosed with care.