Death occurs usually before age 10. Both the juvenile and adult forms have later onset but similar symptoms. In the adult and juvenile forms, psychosis and emotional disturbances are an important part of the illness. The juvenile form is fatal within a few years of diagnosis. The adult form may be drawn out over many years.
Genetic counseling is recommended for parents with a family history of metachromatic leukodystrophy.
Call your health care provider if you have a family history of this disease or if you notice symptoms suggestive of this disorder.