Topical anesthetic may be used on vaginal mucosa prior to submucosal injection. Inhibits depolarization, blocking the transmission of nerve impulses, which reduces pain. Topical preparations are available in spray and ointment form. Interactions None reported Pregnancy B - Usually safe but benefits must outweigh the risks. By increasing electrical excitation threshold, slowing nerve impulse propagation, and reducing the action potential, bupivacaine prevents the generation and conduction of nerve impulses to reduce pain.
Duration of action is significantly longer than lidocaine.
Bupivacaine is available with or without epinephrine. Antibiotics - These agents are used for empiric therapy in STDs, especially given the high incidence of N. gonorrhoeae in Bartholin abscesses. By binding to one or more of penicillin-binding proteins, arrests bacterial cell wall synthesis and inhibits bacterial growth. An alternative monotherapy to ceftriaxone, bactericidal antibiotic that inhibits bacterial DNA synthesis, and consequently growth, by inhibiting DNA-gyrase in susceptible organisms. Indicated for C trachomatis .