Insulin-like growth factor I in the treatment of neurological disease. Cysteine protease initiated cell death precedes disruption of the actin cytoskeleton in hyperglycemic neurons. Clinical and pathologic features of focal myositis. I prevents glucose mediated loss of mitochondrial membrane integrity and programmed cell death in models of diabetic neuropathy. The role of IGF-I in diabetic neuropathy.
Growth factors prevent glucose-mediated mitochondrial dysfunction in glia.