The scaffold with projecting DNA loops appears to correspond to an aggregation of lampbrush chromosome-like chromomeres. The apparent lateral looping of the DNA from the scaffold core implies that the chromosome is regularly compacted along the long axis of the chromosome. The regular compaction along this axis suggests that maps of morphological and molecular chromosomes should be colinear. Compaction that can be achieved by looping must be about 250 fold. Certain DNA sequences along the chromosome must be bound to proteins in an interaction that resists dissociation with dextran sulfate.
Further information Examine an electron micrograph of DNA released from chromatin.
Laemmli's view of chromosome structure.