Increased production of free radicals in the body is known as oxidative stress. Free radicals are continuously formed as a consequence of many oxidative biochemical reactions in the body. In addition, the environment is also a source of free radicals. Damages caused by free radicals Free radicals attack, damage and ultimately destroy almost any material. The rusting of metal, the browning of a fresh cut apple, or the hardening of paint are all examples of the constant bombardment of free radicals and the resultant damage.
Free radicals are inherently unstable, since they contain 'extra' energy.
To reduce their energy load, free radicals, react with certain cells in the body, interfering with the cells' ability to function normally. Free radicals if left undestroyed, would quickly enter into oxidative reactions with different vital cellular components containing lipids, proteins, nucleic acids and carbohydrates. Free radicals attack blood fats which may lead to heart and blood vessel diseases. Thus, the free radical mediated oxidation of LDL cholesterol is a critical link between high blood cholesterol and build up of vessel-blocking plaques. In addition, free radicals may lower the levels of HDL cholesterol, which protect against cardiovascular diseases.