Sperm require a period of maturation in the female reproductive tract before they are capable of fertilizing the egg 2. Capacitation takes 5 to 6 hours in the human 3. Capacitation takes place in the uterus and oviduct 4. Capacitation alters the sperm plasma membrane 5. Acrosome reaction of mammals is initiated as sperm proceed through the corona radiata and approach the zona pellucida 2.
Enzymes loosen the connections between cumulus oophorus or corona radiata cells iii.
Help the sperm to reach the zona pellucida 3. Mechanism used by sperm to penetrate the zona pellucida is not fully understood a. Some investigators think that sperm penetrate this layer solely by the propulsive force of their swimming b. Fusion of sperm and egg A. Zonal reaction 1. Eggs are surrounded by the zona pellucida a.