The Hybrigel Electrophoresis media combines copolymerized Acrydite TM modified DNA probes with a polyacrylamide gel matrix. The copolymerized DNA probes are anchored in the gel, and act as a capture layer for complementary oligonucleotides. Passing a current through the matrix facilitates the hybridization process. Assays Acrydite Gel is a proprietary gel based hybridization system where the Acrydite DNA is polymerized into a gel and serves as a capture probe for complementary or target DNA sequences.
Electric current facilitates the passage of the target sequence through the capture layer.
In a sense the assay is a chromatographic process. Any nucleic acid or nucleic acid analogue that migrates in an electric field can be hybridized to gel-immobilized nucleic acids. Click here to download the Adobe Acrobat Reader .