And that is what this page is all about. The level of fatigue that you feel will be determine in part by the stage of disease you have. For example, if you have bone marrow involvement you'll be even more tired than most because your body will not be able to produce the red blood cells necessary to carry oxygen throughout the body. In addition, if any other organ's have been effected, like lungs or heart, you may have trouble compensating for this which will tire you out. Pain has been noted as a cause of fatigue because it both takes energy to try and forget about or deal with pain and because pain can keep you from getting the sleep you need.
Fevers take energy to fight.
All of this leads to fatigue. I'm very familiar with stress. I could go on and on. There are many things you can do to cope with the fatigue. I can't promise you to be rid of it, I haven't found a miracle cure, but there are things that can be done to manage it.