Part of that response appeared to be temporary. These splenocytes were more responsive to mitogen stimulation than controls. Stimulation of spleen function appears to be the basis for recent clinical application of whole-body exposures of cancer patients to 10 cGy once or twice weekly. Sakamoto and associates note that the activation of immune reactions correlates with tumor regression in some patients. The complexity of recently defined immune factors in radiation hormesis is beyond the scope of this review.
Limited reviews are available.