Variants of GBM include gliosarcomas and giant cell glioblastomas. GBMs occur most often in the cerebrum, especially in the frontal and temporal lobes of the brain. They rarely occur in the brain stem or cerebellum. It is more common in older adults and affects more men than women. Nine percent of childhood brain tumors are glioblastomas.
Glioblastomas can be very difficult to treat.
Methods include surgery, chemotherapy, surgery and steroids. This is the same type of information that is available to physicians and other health care professionals. British Journal of Neurosurgery. 2000 Future directions in the treatment of malignant gliomas with temozolomide. Seminars in Oncology.