This in turn causes WBC count to increase. The kidneys of a person with SLE may not filter waste out of the blood efficiently. Waste products remain in circulation and an increase in waste products in the blood may occur. Excessive amounts of protein may also be lost in the urine. There may be symptoms of headaches, seizures, temporary paralysis, psychotic behavior, or strokes due to involvement of the brain, spinal cord, and nerves.
Joint pain is very common in lupus.
Arthritis-like pain, swelling in the joints, redness, and stiffness are likely to occur. The heart is another area affected by lupus. There may be increased swelling of the extremities, shortness of breath, and accumulation of fluid in the sac surrounding the heart. According to Rhodes, Cardiac complications and abnormalities associated with SLE have been well described. The symptoms do not usually show until advanced disease is present.