The goal of the consortium is to develop high-throughput methods for protein production, crystallization and structure determination. Some defend against disease, while others regulate body functions. Specialized proteins called enzymes drive chemical reactions in the cell, while structural proteins combine to form cartilage, fingernails and hair. It turns out that nearly every molecule of protein produced in the body has to be folded into a specific, three-dimensional shape in order to function properly.
Humans produce thousands of proteins, each with a distinct function and shape.
Some resemble convoluted pretzels, while others are woven into intricate braids. If the molecule is folded incorrectly, oxygen will not be delivered. According to JCSG, detailed, three-dimensional images of proteins will give researchers a clearer picture of how protein structure and function are interrelated.