Please conduct a current literature search and check the appropriate current online database for the most recent quantitative information.
Limited information is available on the chronic effects of chlorine in humans.
Reports from the older literature stated that chronic exposure to concentrations of chlorine of around 5 ppm caused respiratory complaints, corrosion of the teeth, inflammation of the mucous membranes of the nose, and increased susceptibility to tuburculosis. No information is available on the developmental or reproductive effects of chlorine in humans or animals via inhalation exposure. A study reported no adverse effects on growth, lifespan, or fertility in rats exposed to 100 ppm chlorine in their drinking water for their entire lifespan, over seven generations. No information is available on the carcinogenic effects of chlorine in humans from inhalation exposure, and chlorine has not been found to be carcinogenic in oral animal studies. EPA has not classified chlorine for carcinogenicity.