When we put the two together, we ll know which symptoms correlate with which genetic picture. At the same time, we re evaluating the families in Israel who carry dystonia to see if they fit the criteria for the Ashkenazi dystonic gene, or if they map to an unknown gene. We re also trying to identify symptom-less carriers. This work underpins that of the molecular biologists, searching to find exactly where the malfunction lies. Once the exact locations of the genetic changes are pinpointed and their expression studied, the chances are of developing a reliable medication are good, says Dr. Blumenfeld.
Gene therapy is one of the most hyped areas of new-age medicine.
If it leads to successful treatment for people like Robert Weil, his cousin Judith and the four Rosenzweig children, it s surely worth all of its hype and more.