Most peripheral B cells in mice are ligand selected. Retroviral interleukin 4 gene transfere into an interleukin 4-dependent cell line results in autocrine growth but not in tumorigenicity. Membrane bound IgM obstructs B cell development in transgenic mice. A T cell clone which does respond to interleukin 2 but not to interleukin 4. A new V gene expressed in lambda-2 light chains of the mouse.
Lymphokines regulate immunoglobulin isotype expression in an antigen specific immune response.
Cell cooling in flow cytometry by peltier elements. Control of immunoglobulin class switch recombination. Class switch recombination is IgG1 specific on active and inactive IgH loci of IgG1 secreting B-cell blasts. Signal requirements for growth and differentiation of activated murine B lymphocytes. Boehmer and W. Haas, Editors.