The major databases and bibliographic sources were searched for relevant articles together with meetings with specialists. The incidence of prostate cancer is increasing worldwide due to the growing elderly population and because of increased testing for prostate cancer. Many prostate tumours are slow growing.
Histological grade is the best predictor of progression.
The use of diagnosis tests is believed to be increasing. Patients with severe BPH or suspected cancer are referred to hospital specialists. Current trials comparing the three main methods will take many years to determine which is the most effective treatment. Much more research has been conducted into the treatment of advanced disease than localised disease. Progression of disease can be slowed down by starting androgen deprivation as soon as advanced disease is diagnosed.