Intentional misuse or deliberate inhalation may cause death without warning. Vapor reduces oxygen available for breathing and is heavier than air.
Liquid contact can cause frostbite.
Overexposure to the vapors by inhalation may include temporary nervous system depression with anesthetic effects such as dizziness, headache, confusion, incoordination, and loss of consciousness. Higher exposures to the vapors may cause temporary alteration of the heart's electrical activity with irregular pulse, palpitations, or inadequate circulation. Gross overexposure may be fatal. Skin contact with the liquid may cause frostbite. Individuals with preexisting diseases of the central nervous or cardiovascular system may have increased susceptibility to the toxicity of increased exposures.