Finally, the membrane processes in neurotransmission are discussed. Selected readings from the scientific literature are used to illustrate the milestones of molecular biology and the development of techniques and experiments. Protein synthesis and ribosome structure lead into a discussion of mRNA and finally DNA synthesis, with the chemistry of recombinant DNA molecules receiving significant attention. During the course, common experimental methods will be explored, including a discussion of the information available from each method. A discussion of selected modern synthetic methods including additions, condensations, and cyclizations.
Emphasis is placed on the logic and strategy of organic synthesis.
This course deals with the stereochemistry of and the bonding in transition metal complexes of both the classical and organometallic types. The crystal field and molecular orbital theories of bonding in such complexes are treated in detail. Special attention is given to reactions and catalysts. This course provides an introduction to the statistical methods of determining thermodynamic properties of substances from basic information about the atomic and molecular units from which they are formed. Through calculation of thermodynamic quantities and the evaluation of chemical equilibrium constants, broad insights into the kinetic molecular theory and the significance of the concepts of entropy and energy are developed.