For the analysis of cytoarchitectonics we use Nissl stains and anti-NeuN immunocytochemistry. Enzyme histochemistry for acetylcholinesterase and, cytochrome oxidase provide a view of cholinergic neurotransmitter systems and mitochondrial activity. Nerve tracts are visualized with osmium tetroxide and astroglia with anti-glial fibrillary acidic protein immunocytochemistry. New stains are being examined for high-throughput capability and ease of performance to demonstrate other aspects of nervous system structure and function. A particular focus for our screens will be on histological analysis of the aged nervous system.
Hybridization analyses of nervous system gene expression.
D. Goldowitz, R. Wimer and D. Wahlsten, eds. Amsterdam, Elsevier, pp. Mouse chimeras in the study of genetic and structural determinants of behavior. D. Goldowitz, R. Wimer and D. Wahlsten, eds. Amsterdam, Elsevier, pp.