Cerebral edema was not associated with the initial serum glucose concentration, the change in the serum glucose concentration during therapy, or the rate of infusion of insulin or sodium. This is a comprehensive analysis of a large number of children with diabetic ketoacidosis who had cerebral edema. Overall, the differences between these children and the control groups indicate that brain ischemia caused by marked dehydration and hypocapnia has an important role in the pathogenesis of cerebral edema in such children. In terms of therapy, the findings translate into the need for vigorous fluid replacement with isotonic saline and avoidance of sodium bicarbonate. I is a rare inherited disease characterized by a variety of endocrine disorders and candidiasis.
Fat malabsorption develops in about one fifth of patients.
This case report describes a patient with the syndrome in whom severe malabsorption was caused by a deficiency of cholecystokinin-producing enteroendocrine cells in the mucosa of his proximal small intestine. I is uncommon, this report suggests that a deficiency of cholecystokinin-producing enteroendocrine cells in the proximal small bowel can cause severe malabsorption. Bile acid secretion, which is stimulated by cholecystokinin, was low in the patient when malabsorption was severe. This review summarizes what is known about the role of variations in the production, metabolism, and action of estrogen and the sensitivity of breast tissue to estrogen as determinants of the risk of breast cancer in women. All rights reserved.