By binding to one or more of the penicillin binding proteins it arrests bacterial cell wall synthesis and inhibits bacterial growth. An advanced-generation cephalosporin. A disadvantage is relatively high cost. Inexpensive and readily available, but has no real efficacy against Vibrio . Covers Vibrio species well, although coverage not as good for Staphylococcus and Streptococcus species.
Generic versions are inexpensive.
Inexpensive combination agent that covers Vibrio and some Staphylococcus and Streptococcus species. As with doxycycline, many individuals can develop photosensitive skin rashes while on the medication. This is important if the patient is on vacation or lives at the beach and is likely to get significant sun exposure while on the medication. It is not unreasonable to request that the patient return to the ED for a wound check in 2-3 days. Advise patients to walk in the shallow areas of the beach with a shuffling gait.