If your friend expresses concern about his or her looks, be gentle, but acknowledge these feelings. Just your listening may be all that is needed. Try pointing out some positive physical traits. It may make him or her feel better. Be sure to include your friend in decision making whenever posssible.
Illness can bring about a loss of control over many aspects of life.
Don't deny your friend an opportunity to make decisions, no matter how simple or silly they may seem to you. Be prepared for your friend to get angry with you for no obvious reason, although you have been there and done everything you could. Permit this, but don't take it in a personal way. Remember, when a person is very ill, anger and frustration are often taken out on the people most loved because it's safe and will be understood. If you and your friend are religious, ask if you could pray or attend services together.