Do not use on ear, penis, tip of nose, and digits. Relative contraindications include coronary artery disease, cardiac dysrhythmias, and seizure disorders. TAC should not be used on old or contaminate wounds due to intense vasoconstriction that may increase the risk of infection. Use the lowest amount effective for anesthesia to avoid high plasma levels and serious side effects. Avoid systemic absorption.
Excessive doses lead to vasoconstriction.
Safety in the use of pregnant women is not yet established. Patients may fail a urine drug screen for cocaine if tested within 36-48 hours of TAC administration. Topical application only . Apply to the affected area as needed. Give patients dosages commensurate with their age, size, and physical condition.