Investigations span the whole spectrum of reproductive sciences.
Studies of gametogenesis cover organelle biogenesis and cellular remodeling during spermatogenesis and oogenesis and signal transduction systems within germ cells. Several laboratories investigate various aspects of the interaction of sperm with eggs and investigate other events surrounding fertilization. The role of hormones and growth factors during early development is also being examined in several groups. Using a human model of implantation and placentation, the involvement of extracellular matrix proteins and cell surface molecules in these processes is being elucidated. Several programs are involved in identifying genes that are regulated by specific hormones.