We agree that there are shards of material in macrophages in a cellular infiltrate surrounded by fibrosis. We cannot, however, be certain about the nature of this material without further analysis. SI-0485 Thoracic peripheral nerve near capsule. We agree that the illustration shows a peripheral nerve surrounded by connective tissue. There is birefringent material near the nerve but we cannot be certain of its chemical composition.
Further analysis is needed.
There is no inflammatory response to this material. Axillary lymph node with silicone granuloma and other silicone foci. There are droplets of phagocytosed material within giant cells in a lymph node. We cannot conclude what the nature of the material is from this section but its appearances are entirely consistent with silicone. Lymph node with silicone in peripheral sinuses.