It usually shows up in the skin, or in the linings of the mouth, nose, or eye. KS can also spread to the lungs, liver, stomach and intestines, and lymph nodes. KS involves the development of many new, tiny blood vessels. This process is called angiogenesis.
Lesions often occur on the face, arms and legs.
KS on the skin is not life threatening. If it spreads to other places, KS tumors can cause serious problems. In the mouth lining, it can cause trouble eating and swallowing. In the stomach or gut, it can cause internal bleeding and blockages. In the lungs, it can cause a serious cough or shortness of breath.