The effect of these other flavonoids against edema has not been well studied. Also, optimal amounts are not known. A similar effect has been reported with rutin at 20 mg, three times per day. A group of semi-synthetic flavonoids, known as hydroxyethylrutosides , are also beneficial for edema. Refer to the individual supplement for information about any side effects or interactions.
Goldenrod is considered one of the strongest herbal diuretics.
Thus, diuretic herbs are not yet well supported for use in reducing edema. Aescin isolated from horse chestnut seed has been shown to effectively reduce post-surgical edema. Creams applied topically three or more times per day are also sometimes recommended by doctors. Horsetail contains several types of flavonoids that are believed to be responsible for this herb's diuretic action and that help account for its traditional use in reducing mild edema. The volatile oils in juniper cause an increase in urine volume and in this way can theoretically lessen edema.