The erratic pattern of blood sugars that this produced was first described about thirty years ago. This leads to a low blood sugar in the middle of the night and high blood sugars the next morning. Misinterpreted, the response may be to increase the evening insulin. The answer is not to give extra insulin when the blood sugar is high but to decrease the long-acting insulin in the previous dose. To avoid all this, it is probably a good idea to do occasional blood sugars at 3 A.M., especially after vigorous exercise.
High blood sugars before supper are much less likely to be due to a rebound.
There are some advantages in drawing up the regular insulin and the NPH in the same syringe separately. Comments and Feedback . Privacy statement .