I make sure that his teeth and ears are A-OK, that he has no parasites, skin problems or other unhealthy irritations. Then, for 10 days, I give him an antibiotic like tetracycline or whatever the veterinarian prescribes. During the same period, I put a drop of eye solution, such as Visine for watery eyes, in each eye every morning and a tiny dab of eye ointment such as Terramycin every evening. The veterinarian may prescribe better products, but I avoid any with color. A little solution or ointment may help, and a larger amount may increase the staining.
Eye care twice daily is more successful than less often.
If stain is no better or actually worse in three days, a change in eye products may be needed. Also during these 10 days I clean his face twice daily and keep the dog happy. Being very careful not to irritate his eyes and assuring the dog that he is the greatest, I touch a cotton swab to the inner corner of each eye and roll up and remove any hair or matter collected there. With a syringe, I put warm water just on the tear-stained hair and gently dry with a tissue and cornstarch. Then, with the top hair in a knot, I wipe stray hairs away from his eyes with a little petroleum jelly.