A macrolide antibiotic derived from erythromycin. Rapidly absorbed and distributed widely throughout the body.
Food increases the absorption of azithromycin.
A loading dose will achieve steady-state levels more quickly. Mainly excreted unchanged through the bile with a small amount being excreted through the kidneys. Required initial IV therapy in community-acquired pneumonia due to S. pneumoniae , Chlamydia pneumoniae, Mycoplasma pneumoniae, H. influenzae, M. catarrhalis, Legionella pneumophila, and Staphylococcus aureus . Those who can take PO therapy in community-acquired pneumonia due to C. pneumoniae, M. pneumoniae, S. pneumoniae, or H. influenzae. PO for genital ulcer disease in men due to Haemophilus ducreyi.