This villain challenges James Bond. For more about Hollywood and albinos, go here. These are fairly common, can be located anywhere from the shoulder to the waistline, and are present from birth. Off the silver screen, accessory nipples, like other birthmarks, do not indicate evil. Scarring is an old standby for the depiction of evil.
Hair loss is an unfortunate, common occurance for many men and women.
In Hollywood, absence of hair is often used to signify badness. All it took to dispel that image was shearing Harrelson's locks. Note also his chest tattoo. For many people, the thought of a mite infesting their skin is scary or revolting.