It's very rare for more than one child in a family to develop Kawasaki disease. Signs and Symptoms Fever and irritability are often the first indications of the disease. The lymph glands in the neck may become swollen. In some cases, the rash may spread to the face. The rash appears as poorly defined spots of various sizes, often bright red.
Fever continues to rise and fall, sometimes for as long as three weeks.
Bloodshot eyes may develop, and the eyes can become sensitive to light. The palms of the hands and soles of the feet often become red, and hands and feet may swell. Occasionally, a stiff neck will develop. Some children have abdominal pain and diarrhea. When the fever subsides, the rash and swollen lymph glands usually disappear.