Although the exact pathogenesis of HPV is unknown, common theory suggests that the virus gains entry into the genital epithelium through microabrasions caused by trauma sustained during sexual activity. Smooth papular warts Subclinical flat condylomata. Subclinical warts are diagnosed by colposcopy or histology. Latent infection is diagnosed only by detecting HPV DNA with tests such as polymerase chain reaction. Physically ablative therapies remove external warts.
Interferons offer immunomodulatory and antiproliferative effects as well as antiviral activity.
They concentrate on stimulating the immune system to fight the virus.