We approach the problem with multiple tools, encompassing mathematical modelling, laboratory,and field investigations. Some of our recent work is on ground water systems where we are studying the kinetics of microbial transformations of chemicals of industrial importance with the support of industry. We have been investigating plasmid mediated biotransformation with emphasis on the methane mono-oxygenase of the methylotrophic bacteria. Another area of investigation is that of enzyme technology. Microbial enzymes are being used to convert wood cellulose into commercially important products via fermentation processes.
Enzyme productivity is enhanced with genetic techniques.
Adaptive control strategies for optimizing enzyme activity are employed to increase the product yield. One goal of our studies is their application to the development of a strategy for environmentally sound practices for production and use of organic chemicals. The other is the fundamental understanding of ecosystem components in natural systems especially with regard to microorganisms. Vita Dr. Clesceri received her B.S. in Biology from Loyola University and her M.S. in Biochemistry from Marquette University. She received her Ph.D. in biochemistry from the University of Wisconsin where she specialized in Microbial Biochemistry with Marvin J.Johnson.