A fungus ball usually does not require treatment unless bleeding into the lung tissue is associated with the infection, then surgical excision is required. Invasive aspergillosis is treated with a 2 to 3 week course of intravenous amphotericin B, an antifungal medication. Allergic aspergillosis is treated with oral prednisone. Some people may benefit from allergy desensitization. Antifungal agents do not help people with allergic aspergillosis.
Gradual improvement is seen in patients with allergic aspergillosis.
Invasive aspergillosis may resist drug treatment and progress to death. Amphotericin B can cause kidney impairment. Call the health care provider if urine output becomes decreased while receiving antifungal medication, or if fever , chills, headache or worsening symptoms develop. Aspergillosis is a fungal infection that invades and destroys tissue. This type of infection usually occurs in diabetic or immunocompromised individuals.