Molecular biology of receptors and signal transduction events with special emphasis on the growth factors. Introduction to free radical chemistry with emphasis on the importance of free radicals in biological reactions. Lecture, laboratory, and conference. Applies the principles of physics and chemistry to an understanding of the living animal. The physiology of the organ systems of humans is emphasized in preparation for understanding the diseased state.
Emphasis is on critical thinking and a rational approach to problems in experimental biology.
The course begins with neuronal morphology and a review of membrane properties. Neuronal integration is considered from an extracellular viewpoint, including the influence of the extracellular environment and field potentials generated by small ensembles of neurons. Considers the integrative properties of cells as studied using intracellular recording techniques. Electrobiology of the Mammalian CNS G16.2507 Sugimori. Intrinsic and oscillatory properties of neurons in the mammalian central nervous system and the role these properties play in the function of the circuits in which they participate.