This cell line along with HCC1007 is one of our more important cell lines. Worth another click to find out more about these cell lines . Negative for p53 expression HCC1428 harbors homozygous deletion in FHIT gene at 3p14.2. For more information about these deletions, please refer to Ahmadian etal. Cancer Research Vol.
Heavy cultures tend to contain non-adherent cells.
BRCA1 is considered an important player in the breast cancer development, and is located at 17q21. For more information about this mutation, please refer to Tomlinson etal. Cancer Research Vol. To find out more about this cell line, please click HCC1937. Non-adherent cell masses appear as darkly staining cell masses in the following figure.