Ribose may help dramatically improve the quality of life for persons suffering from certain cardiac conditions, and research shows it has a direct effect on heart function for persons suffering from ischemia. Under conditions of cardiac insufficiency blood flow to the heart is diminished. Some individuals have known cardiac insufficiencies, while a great many others may not even know that such conditions exist. In either case, cardiac function may be diminished, energy stores may be low and recovery to peak levels may be slow or never achieved. For these individuals, even simple activities required for daily living may be difficult and exercise may not be tolerated.
Energy recovery is certainly a major concern.
Doses greater than or equal to 2.2 grams per day should be enough to improve nucleotide synthesis and salvage and keep heart ATP levels at their peak. Ribose is only effective, however, if it can reach the cells requiring an energy boost. If circulation to portions of the heart is diminished, it may take longer for enough ribose to reach the affected areas. Therefore, larger doses may be required. In individuals who are concerned about their cardiovascular energy stores, are overly tired following exercise, or are not able to exercise as much or as hard as they like, higher doses may be necessary.