Nausea, fever, hives, chills, urticaria, wheezing, hypotension, chest tightness, stinging at infusion site, hypotension, anaphylaxis. Antibodies may form to the mouse protein found in AHF derived from monoclonal antibodies. Antihemophilic factor contains traces of blood group A and B isohemagglutins. These may cause intravascular hemolysis in clients with types A, B, or AB blood. Both hepatitis and AIDS may be transmitted from AHF prepared from human plasma.
Dosages given are only guidelines.
Prophylaxis of spontaneous hemorrhage. Smaller doses may be sufficient for early hemarthrosis. Dosage should not be repeated. Minor surgery, moderate hemorrhage.