Do some research and planning. Anecdotes are much more effective because they resonate more with readers and viewers. Think about what questions you will be asked. Trust me, there are no more than a few obvious questions. Unpredictable questions generally tend to be rare.
Dumb questions are a different story.
If you get one, avoid being defensive, just educate within your reply. Reporters are people and most have grown up with the same myths, misinformation and stereotypes about our community that we all carry around. Get the facts. Track down any legal facts or statistics that are part of your message and incorporate them into your anecdotes. Easily understood facts and figures are helpful and add credibility to your messages.