At least three types of GP neurones have been found on the basis of electrophysiological characterisation of membrane properties, the presence of voltage dependent 'signature' currents and morphology. The presynaptic modulation of GABA release by enkephalin and dopamine has been the subject of recent studies. Paired whole-cell recordings are now being used to study the interconnectivity of these neuronal subtypes. The role of these interconnections, as well as membrane properties, may be involved in a mechanism by which action potential firing becomes synchronized in animal models of Parkinson's disease. Dopamine D2 receptor mediated pre-synaptic inhibition of striatopallidal GABA A IPSCs in vitro .
Limbic gamma rhythms.
Synaptic and intrinsic mechanisms underlying spike doublets in oscillating subicular neurons. Limbic gamma rhythms. I. Phase locked oscillations in hippocampal CA1 and subiculum J.Neurophysiol. Recurrent excitatory post-synaptic potentials induced by synchronized fast cortical oscillations. USA 94, 12198-12203.