Known neoplasms at application site. Use in wounds that close by primary intention. Use with other topical drugs has not been studied. Use with caution during lactation. Safety and efficacy have not been determined in children less than 16 years of age.
Dose depends on size of ulcer area.
To determine length of gel to be applied, measure greatest length of ulcer by greatest width of ulcer in either inches or centimeters. Calculate amount to be applied at weekly or biweekly intervals depending on rate of change in ulcer area.