Consumer participation will happen if, and only if, consumers perceive that their needs are being met by the Network and other NCI initiatives. NCI must articulate to consumers how the Cancer Genetics Network will fit into the larger context of the work being done to end the cancer epidemic. Although we support basic science, the consumers' focus is on how and when this research will translate into the development of early, reliable detection methods, treatments that prolong life and improve its quality, environmental factors that contribute to cancer, and effective means of breast cancer prevention. These are not just words. Research into genetics, while important, must always have as its endpoint progress in these critical areas.
Many consumer groups are concerned about environmental carcinogens.
It is essential that they know that the National Cancer Institute recognizes that genes do not function in a vacuum. Identifying the factors that affect penetrance and expression of mutations is critical to finding effective means of reducing an individual's risk. Such research may have widespread implications for sporadic, as well as hereditary breast cancers, and will potentially benefit everyone, as everyone is at risk. Before the initial RFA is issued, the Consumer Advisory Committee feels strongly that there are other areas of concern that must be considered. The Network must collect data relevant to research into the environmental factors affecting penetrance and expression of gene mutations.