The adrenal gland weighs approximately 4-5gm in wt. Outer-most zona glomerulosa. Dark compact cells. Normal adrenal Gross from glass slide. Fasciculata and reticularis are a functional unit that secrete glucocorticoids and sex steroids.
Main glucocorticoid is cortisol.
Main androgen is testosterone. ACTH is a 39 amino acid peptide that controls secretion of glucocorticoids and sex steroids. In ACTH, hypersecretion hyperplasia of fasciculata and reticularis are seen. Bronchogenic carcinomas and other neoplasms may secrete ACTH-like substances. Mineralocorticoids Are controlled by potassium and angiotensin levels.