Probably not, particularly if it's just one small business. But there might be other possibilities. Perhaps the potential employee's job is really just talking on the telephone, selling products. Maybe the job can be done from home, and there is no need to even be in the office. It may be.
Employees have to ask for reasonable accommodations.
Once they do, the employer has the right to consider the requests, and make counter-offers that the employer might see as more reasonable. If the employer and employee can't agree, then the employee might want to consider bringing suit. However, to win, the judge or jury will have to find that the employee's request was reasonable, or that the employer's counter-offers were not sufficient. The employer, however, MUST at least engage in good faith attempts with the employee to come up with a reasonable accommodation. Failure to do so by the employer is a violation of the Disability laws.