Since it can be used on both Windows and Macintosh systems, connectivity is maximized. The bridge between the hardware and software is the Global Controller, which is essentially a mini-server consisting of a computer with a hard drive for collecting and storing data and an operating system that provides Internet capabilities. The Global Controller monitors electrophoresis and stores data from runs initiated using e-Seq. Once electrophoresis is up and running, the remote computer can be used for other tasks. At the end of the run, the controller sends the data to the remote computer for sequence readout and various automated downstream analyses.
Image galleries provide a means for easy gel image comparisons.
DNA Analyzer PE Biosystems, a pioneer of DNA sequencing, introduced the first automated sequencer in 1986. The 3700 Capillary Array is made up of 96 primary and eight reserve high-performance capillaries. This process contributes to capillary longevity, specified to last through 300 runs. This polymerase is an enhanced version of an old favorite that exhibits very low 5'-3' nuclease activity, resulting in reduced background noise and obliteration of false terminations. The fragments are detected in solution just a few microns from the ends of the capillaries using a sheath flow method, which provides continuous laser excitation of the samples.