Your body needs periodic breaks to rest and recover. Taking a break does not mean you have to stop working, you could make a trip to the copier, talk to a colleague, make some phone calls, etc. It is also very important to change positions periodically. Sitting in one position or leaning on your arms for an extended period of time can interfere with circulation. Moving around can help with circulation and prevent you from putting pressure on one location for an extended period of time.
Eye strain can also occur from heavy computer use.
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