The current focus is in further understanding of a newly discovered self, perpetuating link among hemodynamic alterations, mesangial vasoactive system, and proinflammatory cytokines and growth factors elaborated by the glomerular mesangium. Studies are aimed at delineating the role of this ubiquitous peptide, in cell proliferation, growth arrest, apoptosis, regeneration, and differentiation in the gastrointestinal tract. Beta by hemodynamic shear-stress forces in vivo. An in viva study.
Growth hormone upregulates gastrin and peptide yy gene expression.