Chomaffin cells are also referred to by some as pheochromocytes. Chromaffin cells are columnar in shape and rather basophilic. At higher magnification, they are seen to have a granular cytoplasm due to hormone-containing granules. The adrenal medulla is richly innervated by preganglionic sympathetic fibers. Additionally, small numbers of sympathetic ganglion cells are commonly observed in the medulla .
Ganglion cells are round or polygonal with prominent nuclei.