Alcohol Frequent and heavy use of alcohol has an impact on many health disorders and diseases. However, when it is combined with tobacco, the two substances are believed to have a synergistic effect whereby one substance significantly amplifies the hazardous effects of the other. Genetics Genetics influence the development of some cancers, as it predisposes one to the possibility of acquiring the disease. Through genetics, it is possible to inherit gene mutations that promote growth of cancer cells. However, genetics are responsible for less than five percent of the development of fatal cancers.
Genetic variables are higher within races than between.
Mortality The cure rates for cancer of the oral cavity varies depending on the stage and site. Early stage cancers are thought to have a cure rate as high as 90 percent. Moderate or advanced cancers may be controlled by combined modality therapies such as surgery or radiation or both. In the case of the latter, the survival rate differs and is dependent upon the site and the extent of spread of the disease.