A substantive amendment to this systematic review was last made on 27 August 1997. Cochrane reviews are regularly checked and updated if necessary. This section is under preparation and will be included in the next issue. Data analysis was done in accordance with the standards of the Cochrane Neonatal Review Group. No differences are reported in the risk of intraventricular hemorrhage, patent ductus arteriosus, necrotizing enterocolitis or retinopathy of prematurity.
Few data are available on long-term followup of treated infants.
Infants who receive prophylactic natural surfactant extract have a decreased risk of pneumothorax, a decreased risk of pulmonary interstitial emphysema, a decreased risk of mortality, and a decreased risk of bronchopulmonary dysplasia or death. This is an abstract of a regularly updated, systematic review prepared and maintained by the Cochrane Collaboration. Update Software Ltd. All rights reserved.