The cause of CLL is unknown. No relationship to radiation, carcinogenic chemicals, or viruses has been determined. An increased incidence of CLL has been noted in people with certain autoimmune diseases . The incidence increases with age to 15 out of 100,000 by 70 years old. There is no known way to prevent this disorder.
Early disease requires no specific therapy.
Chemotherapy or radiation may be indicated for fatigue , anemia , thrombocytopenia , or enlarged lymph nodes that are troublesome. Blood transfusions or platelet transfusions may be required. The stress of illness can often be helped by joining a support group where members share common experiences and problems. Progression of the disease is slow. A small amount of bone marrow is removed during a bone marrow aspiration.