Further extension into deep arachnoid surrounding blood vessels in gray and white matter and disruption of the pia-glial membrane may result in brain parenchymal infiltrates. A phenotype that is CD45, CD43, CD68, and myeloperoxidase positive and CD20 and CD45RO negative is characteristic. In our patient, bone marrow cytogenetic study on initial presentation was normal. On T1-weighted MR imaging, the lesions look isointense with the gray matter, and enhance homogenously. On T2-weighted images, the lesions are isointense with the white matter.
Lesions showing similar signal intensity to the brain include meningeomas, and metastases.