Any condition presenting a risk of hemorrhage, such as recent surgery or biopsies, delivery within 10 days, ulcerative disease. Arterial emboli originating from the left side of the heart. Also, hepatic or renal insufficiency, tuberculosis, recent cerebral embolism, thrombosis, hemorrhage, SBE, rheumatic valvular disease, thrombocytopenia. History of significant allergic response. Safety in children has not been established.
Geriatric clients have an increased risk of bleeding during therapy.
Nausea, headache, breathing difficulties, bronchospasm, angioneurotic edema urticaria, flushing, musculoskeletal pain, vasculitis, interstitial nephritis, periorbital swelling. Infusion DVT, pulmonary embolism, arterial thrombosis or embolism. Arteriovenous cannula occlusion.