Many thanks, Lynn. Unfortunately, the disease progression is still not completely understood. Researchers continue to study the pathological evolution of the hepatitis C virus. As the hepatitis C virus affects the patient s liver, liver tissue is damaged. Two histological stages of chronic liver disease are fibrosis and cirrhosis.
Fibrosis is seen as scar formation in the patient s liver.
The scars occur as the liver tries to repair damaged tissue. Cirrhosis is a condition where the liver becomes permanently scarred. Cirrhosis interferes with normal liver function, and many times, the patient is symptomatic. Necrosis is dead liver cells. Fibrosis Fibrosis is an accumulation of fibrous tissue resulting from an imbalance between several types of liver cells.