Of these, measurement of the depth of the lesion is most important. OK-432 is available in 0.1 mg vials or 0.5 mg vials. Intracystic fluid is aspirated using a 25 or 23-gauge needle. A typical response includes a low-grade fever of 38 to 39 degree centigrade approximately six hours after injection. An inflammatory response may develop two to five days after the initial injection.
Fever is transit and responds to antipyretics.
If this response is not seen, the injection of OK-432 solution is repeated seven days after the initial injection.