It is moderately toxic by ingestion, subcutaneous, and intravenous routes. It is a skin, respiratory, and eye irritant. The substance may cause effects on the central nervous system and the acid-base balance in the body, resulting in delirium or tremors. Repeated and prolonged contact with the skin may cause dermatitis. Anyone sensitive to aspirin should avoid contact with this material.
Dust explosion is possible if in powder or granular form, mixed with air.
Volatility is noticeable above 50 to 60 degrees F. Materials should only be used and handled in a controlled environment with local exhaust or in a fume hood. Safety goggles and eye protection should be worn when handling the materials. In case of a spill the dust may be swept into containers while minimizing dispersion. The material may be moistened first to prevent dusting. Keep these materials away from strong oxidants.