Likewise any actions that arise from defilements create suffering. Our very existence itself is suffering. No matter where we go or what we have or who we are with, we can never be fully satisfied. In this way even feelings which normally we consider to be indifferent are also suffering. We suffer because of our defilements, and these come from our lack of wisdom, our ignorance of the true nature of reality.
Ignorance is the most basic defilement.
It is because of our ignorance that we are caught up in duality and it is from ignorance that attachment and aggression arise. From these three main defilements of ignorance, attachment, and aggression come the other defilements such as pride, meanness, jealousy and so forth. Suffering is the crop which grows from the seed of our negative actions. The exact nature of the suffering depends on the amount of negative actions committed and also on the nature of the actions. These may result in one falling into the hell realm or the hungry ghost or the animal realm.