Infections include lower respiratory tract infections, bone infections, endocarditis, septicemia, and skin and skin structure infections. Alone or in combination with aminoglycosides to treat endocarditis caused by Streptococcus viridans or S. bovis. Must combine with an aminoglycoside to treat endocarditis due to Streptococcus faecalis. Prophylaxis of bacterial endocarditis in pencillin-allergic clients who have congenital heart disease or rheumatic or other acquired or valvular heart disease if such clients are undergoing dental or surgical procedures of the upper respiratory tract. The parenteral dosage form may be given PO to treat pseudomembranous colitis or staphylococcal enterocolitis due to C. difficile.
Geriatric clients are at a greater risk of developing ototoxicity.
Urticaria, pruritus, macular rashes, exfoliative dermatitis, Stevens-Johnson syndrome, toxic epidermal necrolysis vasculitis. Drug fever, hypersensitivity, anaphylaxis. IV Severe staphylococcal infections. Prophylaxis of bacterial endocarditis in dental, oral, or upper respiratory tract procedures in penicillin-allergic clients.