This syndrome is generally mild. However, stopping abruptly can produce a wide range of symptoms including convulsions, especially if high doses have been used for a prolonged period of time. Benzodiazepines may also be misused and abused. Generally, benzodiazepines are well tolerated and have a wide margin of safety. But some people may experience drowsiness, lethargy dizziness or difficulty with co-ordination.
High doses lead to heavier sedation and can impair both mental sharpness and physical co-ordination.
Lower doses are recommended for older people and for those with some chronic diseases, since they may be more sensitive to medications and may metabolize them more slowly. It has also been suggested that benzodiazepines can impair the ability to learn and remember new information. Studies show that anti-anxiety agents, even when correctly prescribed, may interfere with the ability of some users to perform certain physical, intellectual and perceptual functions. Most side-effects usually occur early in treatment and wane over time. For these reasons, individuals should assess their response to benzodiazepines before they operate a motor vehicle or engage in tasks requiring concentration and co-ordination.