Laboratory tests are not always accurate and blood tests do not necessarily reflect nutrient levels within specific organs or tissues, particularly not within the nervous system. Therapeutic trial and dose titration is often the most practical test. Biochemical individuality is a central precept of Orthomolecular Medicine. Hence, the search for optimal nutrient doses is a practical issue. Megadoses, larger than normal doses of nutrients, are often effective but this can only be determined by therapeutic trial.
Dose titration is indicated in otherwise unresponsive cases.
Environmental pollution of air, water and food is common. Optimal health is a lifetime challenge. Nutrient related disorders are always treatable and deficiencies are usually curable. To ignore their existence is tantamount to malpractice. Don't let medical defeatism prevent a therapeutic trial.