Food decreases absorption of the drug. Stomach pain, stomaitis, ulcers in the mouth, nausea, vomiting, pancreatitis, hepatitis, peripheral neuropathy, hyperglycemia. Abdominal pain, anemia, nausea, and sore throat, GI intolerance, muscle weakness, granulocytopenia, leukopenia, isomnia, myalgia, severe headache, hepatic function impairment. Take on empty stomach, at least 30 min. Take it only with water.
Food decreases absorption.
Avoid alcohol as it exacerbates toxicity. Ulcers in the mouth, diarrhea, nausea, vomiting, stomatitis, dry mouth, GI irritation, hyperglycemia, gout, pancreatitis, hepatitis, peripheral neuropathy, abnormal liver function tests. Avoid use of alcohol. Loss of appetite, nausea, vomiting, diarrhea, ulcers in the mouth or throat, pancreatitis, hepatitis, CNS changes, peripheral neuropathy, renal function impairment, hepatic disease. Abdominal pain, nausea, vomiting, diarrhea, loss of appetite, fever, rash, headache, sore throat, and cough, peripheral neuropathy.