Molecular Diagonostics Molecular Diagnostics Molecular diagnostics is becoming increasingly important worldwide. In the U.S., several manufacturers have begun to launch commercial diagnostic kits for various infectious agents. These kits are for the most part manual in operation and require skilled labor as well as specialized equipment. For molecular diagnostics to gain wider acceptance, automated systems will have to be developed.
Instrumentation is needed for sample preparation, amplification and molecular target detection.
Sarnoff has recently designed systems to enable routine laboratory workflow in a molecular diagnostics laboratory. Features of the systems are described in Table 1 and Figure 1. Table 1 1. Sample Preparation Fully automated instrument designed and assembled. Closed, contained disposable cassette for sample processing designed and fabricated.