The AUP may be approved following resolution of these questions. Completion of the AUP review process can take as long as 60 days. The length of time for review is variable and is dependent upon how thoroughly the AUP was prepared, how well concerns were addressed, and how quickly responses are received. Protocols that use hazardous materials will require additional review from safety committees. All AUPs are approved for a duration of three years .
Federal regulations require a complete review of animal research projects every three years.
The ULAC Committee fulfills this obligation by requiring investigators to submit a new AUP after three years for continuing projects. Reviews must be conducted at least annually. The Annual Review Form may be downloaded from this site. Historically, question 6 is the most challenging for investigators to answer. The purpose of review is to ensure that no changes have taken place inadvertently in the approved activity that might require further review and that any new requirements of the PHS, USDA, or the institution are transmitted to the investigator.