Searches can be based on enzyme activity or, if appropriate, nucleotide sequence based. Libraries can be phage, plasmid or phasmid based. Inserts within a two-fold range of your specified optimal size are cloned. Primary titres of the library vary, but are typically greater than 1 million. This can be amplified as required.
Libraries can be off the shelf or custom made on an exclusive or non-exclusive basis.
You can screen the library, you can tell us how to screen the library, or we can advise on and agree a search method. We use a variety of enzyme assay and sequence assay techniques. We can give you uncharacterized clones containing your enzymes or small amounts of purified enzyme. We can even quantify the enzymic activity under various conditions for you. In short, we can provide the library for you to do as you wish, or we can provide the enzyme having the characteristics that you specified.