There are two major problems with the use of IV Ig. First, it is very expensive. Second, it is a blood product, and carries with it the risk of transmitting various blood borne disorders including AIDS and hepatitis. There are many other side effects as well, some serious, such as anaphylaxis in patients who harbor low IgA levels with antibodies to IgA, renal failure etc. The effects are by no means spectacular, and he was unable to show a benefit in favor of the drug.
Further studies are in progress.
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