We do research in the emerging field of bioinformatics, using computation to analyze genome sequences, expression datasets, and macromolecular structures. Much of this work is encapsulated in the GeneCensus system, which presents various statistical comparisons of the genomes sequenced so far. Datamining expression datasets and other functional genomics information is a second major focus of the lab. We do detailed analysis on them that is closely coupled to the comparative genomics work.
Macromolecular motions is our third focus.
To further analyze the variability of each of the folds in the protein partslist, we have developed a database system for collecting motions and measuring structural variability. Our motions analysis includes web movies generated by a server and free software for analyzing macromolecular geometry , particularly packing. We disseminate our research through published papers and on-line lectures and courses .