Almost 300 million cases of malaria occur worldwide annually, and there are more than 1 million deaths per year from the disease. Chloroquine was the main drug used to treat malaria for decades, but the disease's increasing resistance to the drug has forced its replacement in parts of the world. Safe, effective, and affordable options are quickly running out. With current smoking patterns, about 500 million people alive today will eventually be killed by tobacco. While studies in the 1960s suggested that one in four long-term smokers died from their habit, studies in the 1990s suggest that the real ratio is now about one in two.
Immunization is the greatest public health success story in history.
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