They are partly excreted as the unchanged drug and partly as metabolic products in the urine. They are excreted mainly by the kidneys through glomerular filtration. It is used to treat Ulcertive colitis and Crohn's disease. Contra Indications Sulfasalazine is contraindicated in hypersensitivity to the drug,intestinal obstruction, urinary obstruction, SLE and blood dyscrasias. Precautions Precaution to be taken in hepatic damage, renal damage, diabetes, pregnancy and lactation.
Interactions Reduces the serum levels of digoxin.
Interferes with absorption of folic acid. All rights reserved.