My project focuses on the survival of the Brucella abortus inside the macrophage.
Macrophages are white blood cells in animals.
When animals are infected with any kind of microorganism, macrophages will first try to eliminate the foreign invaders. Macrophages will engulf the bacteria and form a compartment called phagosome . After the formation of the phagosome, the lysosome and phagosome fusion occurs to eliminate the microorganisms. Lysosome is an acidic organelle inside the marcrophages. It contains many acid hydrolases that can degrade many materials.