In contrast, the proliferation of immune T cells in the presence of Listeria was inhibited in vivo and in vitro by lead-treated macrophages. The effect of lead acetate on the immune response in mice. Immunity to intracellular bacteria. Effect of lead on macrophage function. Activated T cells enhance nitric oxide production by murin splenic macrophages through gp39 and LFA-1.
Lead inhibits nitric oxide production in vitro by murine splenic macrophages.