Pediatric Dosage Handbook. Ciarallo L, et al.
Magnesium sulfate is used in the treatment of moderate to severe exacerbations of asthma.
Magnesium is a cofactor in over 300 enzymatic reactions in the body. In heart muscle, it acts as a calcium channel blocker. In smooth muscle, it acts as a muscle relaxant. When given intravenously, it promotes bronchodilation. It should be noted that deep tendon reflexes are blunted with magnesium sulfate injection.