He was down to 112 pounds when it was time for his annual physical examination. He didn't rush me to the hospital, but he did warn me that I should gain some weight. Extra systoles are not usually life-threatening, but they can be. I immediately went on an eating binge. Currently, my target weight is 120 pounds, and I rarely go above 123.
Laboratory animals are in protected environments.
However, people who are living workaday lives may be subject to stresses and vulnerable to conditions that could make hypoglycemia or weight-loss due to a disease more dangerous. Best believes that keeping his weight between 119 and 123 pounds provides him with a certain buffer against such events. He also suspects that there may be an important difference between CRAN that is imposed upon laboratory animals and CRAN that is a voluntary practice-in short, voluntary CRAN can create psychological stress. In fact, hypercortisolism is seen in CRAN animals and in anorexics, he notes. One theory of aging makes a strong case for the idea that stress and glucocorticoids play a key role.