If so, the individual shall provide one copy for their faculty or student health file. Research studies indicate a lower seroconversion rate with older and overweight individuals. Any drug agent can react in the body to produce unpredictable, harmful, and sometimes unexplainable responses. No drug agent is totally safe and absolutely free of toxic effects. The recombinant hepatitis B vaccines are derived from only the HBsAg portion of the viral genome and do not contain potentially infectious viral DNA or complete virus particles.
Fewer persons experience mild constitutional symptoms.
Careful epidemiologic studies showed that no severe acute or chronic adverse reactions, including neurologic conditions such as, Guillian-Barre' syndrome, can be clearly attributable to hepatitis B vaccination. Also, no serious adverse reactions have been associated with the small residual amount of yeast-cell protein in the recombinant vaccine. When an adverse reaction occurs, it is usually within seconds to minutes after exposure to an antigen. These reactions may range from mild, self-limited symptoms to shock to immediate death. To prevent the possibility of adverse reactions, all health care providers should obtain a history of drug sensitivity from all individuals prior to administering vaccines.