Using a total of 150 mg per day, French researchers reported that women with CVI were helped in a double-blind trial. Very few doctors working with herbal medicine are aware of these and other double-blind studies supporting the use of OPCs for people with CVI because virtually all publications of these data are in French. These studies appear in obscure French medical journals not readily available to healthcare professionals. Nonetheless, the research has been consistent and OPC-containing grape seed extract products are available. Another traditional remedy for vein problems is butcher's broom .
Gotu kola is another herb recommended by some herbalists for chronic venous insufficiency.
Refer to the individual herb for information about any side effects or interactions. For the convenience of the reader, the information in the table listing the supplements for particular conditions is also categorized. Unkauf M, Rehn D, Klinger J, et al. Investigation of the efficacy of oxerutins compared to placebo in patients with chronic venous insufficiency treated with compression stockings. Diehm C, Trampisch JH, Lange S, Schmidt C. Comparison of leg compression stocking and oral horse-chestnut seed extract therapy in patients with chronic venous insufficiency.