The Amendments also specify that the CCL must be published after consultation with the scientific community and after notice and opportunity for public comment. The list is comprised of contaminants that are known or anticipated to occur in public water systems. Contaminants for future regulation will be identified from this list. The SDWA requires that EPA select at least five contaminants and determine whether or not they should be regulated by 2001. The Agency is also required to re-evaluate existing drinking water regulations every six years.
Infants also tend to be more susceptible than adults.
This RFA solicits research on the dose-response characteristics of subpopulations susceptible to methemoglobin formation as compared to the normal population and research on whether the response to mixtures of exogenous methemoglobin inducers is additive or synergistic. Proposals might also consider species differences in metabolism of methemoglobin inducers since species differences in metabolism may contribute to sensitivity. Neurotoxicity of Al and Mn. In order to better characterize the human health risk from aluminum and manganese, research is needed to determine factors that influence the occurrence of various aluminum or manganese complexes, the relative influence of such complexes on the distribution of aluminum or manganese in the body, and the dose-dependent contribution of such complexes to neurotoxic effects. Pharmacokinetics of CCL chemicals.