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Fanconi syndrome is an impairment in proximal tubular function of the kidney.
This impairment causes certain compounds, which should be absorbed back into the bloodstream by the kidneys, to be excreted in the urine instead. Some compounds that may be lost in the urine include glucose, amino acids , uric acid, and phosphate. Another problem that may result is dehydration caused by excess urination. Fanconi syndrome can be genetic or acquired later in life. Cystinosis is the most common cause of Fanconi syndrome in children.