Yale University, New Haven.
Insect wings have wing veins which appear net-like structure.
Each species has a specific pattern of wing vein which is generated with high fidelity in development. In Drosophila , it is known that the inter-vein consists of two layers of thin epithelial sheet and the vein includes more packed cells. Wing vein formation is known to require the Notch signaling pathway. We have performed a modifier screen of P-element insertion lines to identify genes modifying deltex in a dominant fashion. Phenotypic analysis suggest the involvement of these genes in wing vein formation and possible functions in Notch signaling.