This classification scheme accurately predicts the survival of untreated patients, but is not as reliable in predicting outcome after treatment. Although chemotherapy often can shrink low-grade lymphomas, the cancer usually recurs within five years. Recurrent tumors can also be treated with chemotherapy or radiation, but over time, low-grade NHLs tend to become more aggressive and less responsive to therapy. Consequently, these types of lymphomas are not cured with currently available treatment. Chemotherapy may cure many types of these lymphomas.
Doctors determine the stage of the cancer according to the number and location of tumors.
Biopsies of the bone marrow and lymph nodes often are necessary. Younger patients also usually fare better than older ones. Experts predict that this information will soon foster a new classification scheme that more accurately predicts outcome. Treatment Varies Doctors tailor treatment of NHL to the type of tumor, the stage of the disease, and the patient's age and general health. Most patients receive chemotherapy, radiation therapy, or both.