Try to talk to someone who works for the organization to determine culture. For example, a financial institution vs. an art museum may indicate a different style resume. The trick is to think as your potential employer. Imagine what they consider to be most important in the job. Your thorough research will shine through here.
Employers read scores of resumes.
Critical information about your suitability for the job must be easy for them to locate. Put the most relevant information first. A resume should detail what specific ways your qualifications match the needs of the employer. Employers want specifics. Stress your results.