Basic concepts of the development and function of the immune system are integrated with case material to illustrate how the immune system causes and prevents a variety of endocrine, renal, dermatologic, neurologic, and musculoskeletal diseases, and how organ and tissue transplantation can be used to restore normal function following destruction of particular organs or tissues by immune or other mechanisms. Weekly problem sets based, wherever possible, on case reports and publications drawn from the clinical literature concerning the topics covered in lectures and case presentations during the week. Emphasis is on application of the fundamental concepts of immunology to the clenical problems under consideration. Infectious Basis of Disease - Presentation of the spectrum of human illness induced by viruses, bacteria, fungi, and medical parasites, including protozoans and helminths. Classsification, epidemiology, transmission, pathogenesis, diagnosis, treatment, control, vaccination, and other preventative measures.
Emphasis is on the syndromic approach to disease.
Lectures, demonstrations, lab sessions, and small group evaluation of clinical correlates. Animal Viruses - For graduate, medical and advanced undergraduate students. The structure, molecular biology, and genetics of RNA and DNA animal viruses. Lectures on the molecular biology of virus replication and gene expression and the nature of the host-virus interaction. Concise treatment of eukaryotic molecular and cell biology in the context of viruses.