It is naturalized in the eastern United States. It is used in tomato sauce to add a hot and peppery taste. It adds dimension to yeast breads, marinated vegetables, roasted meats, and fish. Oregano is a perennial, and can be propagated by seeds. Direct seed in the garden and do not cover seeds since they need sunlight to germinate.
Flavor can vary a lot among seed propagated plants.
It is better to propagate by root divisions or cuttings from plants that are known to have strong flavor. It requires a site with full sun, and well-drained soil with a pH of 6.8. Sprigs of oregano can be cut off when the plant is at least 6 inches high. In June, vigorously grown plants can be cut back to the lowest set of leaves. Plants will generally leaf out after two weeks and can be cut back again in August.