Number of neutrophils decrease greatly with overwhelming infection , resistance exhausted , approaching death . Ratio of segs to bands Shift to left Increased bands Means acute infection, usually bacterial. Body is unprotected against invading agents . Requires reverse isolation. Activated by allergic reactions, foreign proteins and parasites .
Eosinophils disappear with corticosteroids .
Eosinophilic myelocytes found only in leukemia or leukemoid pictures . Basophils Concentrated in connective tissue and pericapillary areas. Release heparin, bradykinin, serotonin and histamine . Mediate allergic reactions . Help keep inflammatory substances at site .