Systemic steroids generally have not been found to be effective. Sulfapyridine has had similar effects as dapsone. The IgA levels responded to PLEX treatment followed by consolidative doses of cyclophosphamide. This treatment might be promising for the control of severe EED that is not controlled by dapsone. A strict gluten-free diet was shown to help achieve full healing of a patient with celiac disease for whom dapsone therapy was not completely effective.
Dosage depends on each patient.
Optimal dosage should be determined by the physician. Available for oral intake in 25 mg and 100 mg scored tablets. Dapsone is not considered to have an effect on the growth and development of the child. Has also been used for management of many disorders including livedoid vasculitis and leprosy. Its presumed mechanism of action is as an antiinflammatory and as a vasodilator.