Compilation of the database entailed a survey and analysis of the scientific literature on anti-tumor activity in vitro and in vivo of various natural and synthetic substances. An ability to inhibit metastatic spreading of a tumor was also taken into account. The database contains information relevant to understanding the experimental system in which the substance was evaluated. Such parameters as the species and strain of animals, routes, administration dosage, testing schedule, and strains of tumor cells in culture are included in the database. Different sources, including abstracts of regional symposiums in the former USSR and other countries published in Russian and languages of former Soviet republics, were employed in the data collection process.
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