Clindamycin is used to treat acute toxoplasmosis, although it may not be as effective as pyrimethamine-sulfa. Clindamycin is also used as an experimental treatment for active PCP pneumonia. Clindamycin is used for treatment of skin infections, respiratory tract infections, septicemia, abdominal infections, gynecologic infections, and topical treatment of severe acne. Side effects Clindamycin may cause nausea, vomiting, diarrhea and mild rash.
IV administration can cause a bitter taste in the mouth.
Dosage Clindamycin comes in oral, injection and ointment formulations. The drug does not significantly cross the blood-brain barrier, but it crosses the placenta and enters breast milk. Clindamycin is mostly processed in the liver, so it should not be prescribed if you have liver impairment. Safety of the drug in pregnant or breast feeding women is not established. By mouth, adults are prescribed 150-450 mg every 6 hours.