Many individual Microdipodops live long periods, if not their entire lives, without drinking water. At best they can obtain only drops of dew or, occasionally, succulent plant tissues. Like many other desert rodents, they can derive sufficient moisture from their food as it is metabolized. Annual home range averages 6,613 sq meters for males and 3,932 sq meters for females. Individuals of both species seem to be basically solitary and are aggressive toward conspecifics.
Kangaroo mice are gentle and adapt well to captivity.
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