The dose of Sinemet need not be reduced, Comtan should be added to each dose of Sinemet. After a period of time, the period may be a day, a week, or a month, you and your doctor, based on how well you respond to Comtan, will be able to determine whether or not your doctor should reduce the dose of Sinemet. In this instance you will be taking fewer doses of Sinemet. The question of whether Sinemet should be reduced, the amount, if any, of Sinemet to be reduced, and the manner, if any, of how Sinemet is to reduced, can only be decided by your doctor. After a period of time, the period may be a day, a week, or a month, you and your doctor, based on how well you respond to Comtan, will be able to determine whether or not the doctor should maintain the current Sinemet dose, further reduce the Sinemet dose, or increase the Sinemet dose.
Hallucinations arise from over stimulation, or over-excitation, of certain regions of the brain.
Any of us, under sufficient provocation, can have hallucinations. Including the infamous pink-elephants. Travelers lost in the dessert, sailors marooned on a lifeboat, or anyone deprived of food, water, and sleep, may have delusions, they see mirages, they mistake one thing for another seeing water where there is no water. As Comtan does not enter the brain, Comtan, by itself does not cause delusions or hallucinations. Comtan, by blocking, inhibiting COMT, delays, retards the breakdown of levodopa This prolongs levodopa s action, increasing levodopa s entrance and availability in the brain.