Thus, the neurotransmitter will stay in the junction longer, and is better able to stimulate the muscle to contract. However, these drugs seem to be less effective in reducing the ocular symptoms than those related to other parts of the body. Steroids and other immunosuppressants such as azathioprine have been successful in reducing ocular symptoms, and in slowing the worsening of the disease over time. These medications are not without side effects, and need to be closely monitored by the treating physician. In some cases, removal of the thymus gland may help the disorder.
Females tend to be more commonly affected.
Multiple systems throughout the body can show symptoms. Granulomas, or inflammatory nodules, develop in organs and throughout the body. Chest X-rays are commonly monitored in sarcoidosis, since nodules in and around the lungs can be visualized. Skin nodules can occur, as well as muscle aches, generalized fatigue, and low grade fever. Less commonly, neurological and central nervous system involvement can occur, potentially affecting the visual system.