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You may want to just check into a room and stay for the party at Sam's Town on May 5. Cinco de Mayo Celebration Morning radio personalities Mark and Mercedes play host to what is being billed as the biggest Cinco de Mayo party in Vegas. 7th Annual Fiesta de Mayo Celebration Bring your antacid for the margarita pie, jalapeno pepper and taco eating contests. Luckily, these are three separate contests. Along with live music, contests, Tecate beer and fajitas, the Cuervo Girls will be in attendance handing out Cuervo Margaritas, of course.