A manuscript has been prepared by Dr. Tripodi and this has been approved by the Subcommittee as an SSC publication in Thrombosis and Haemostasis. It is hoped that the reference plasmas will be officially established by the end of 1997. Two presentations were given describing the practice and problems of control of oral anticoagulants in different countries. Seventy percent of Japanese hospitals use the thrombotest for anticoagulant control. Results are converted into INRs by means of an equation.
Good correlation is claimed between INR and thrombotest.
The usual therapeutic range is 2.5-3. 5. The bleeding risk may be accentuated by frequent concomitant usage of antiplatelet drugs. Russia has its own thromboplastins. These are derived from human brain tissue and have an ISI close to 1.0. Monitoring of oral anticoagulant control is performed by determination of the prothrombin index.