Both studies looked at H. pylori infection in patients with gastric cancer and matched controls. Odds ratios for the association between gastric cancer and H. pylori infection were 3.6 and 6.0. The study looked at the relation between the prevalence of H. pylori infection and gastric cancer rates in 17 populations from 13 countries. A significant correlation was found between the infection rate and gastric cancer incidence and mortality. There are many problems associated with such a strategy.
Gastric cancer has a complicated aetiology.
H. pylori infection is certainly an associated factor, but there is no reason at present to consider its use in screening for gastric cancer. Nomura et al. No evidence whatever for increased quality or effectiveness for H. pylori screening for gastric cancer. Should exclude specifically from specifications. These antibodies can be detected in serum by binding the antibodies to purified H. pylori antigen, followed by detection of the human immunoglobulins.