See appropriate sulfonamide labeling for prescribing information. Erythromycin is effective in eliminating the organism from the nasopharynx of infected individuals, rendering them noninfectious. Some clinical studies suggest that erythromycin may be helpful in the prophylaxis of pertussis in exposed susceptible individuals. As an adjunct to antitoxin in infections due to Corynebacterium diphtheriae, to prevent establishment of carriers and to eradicate the organism in carriers. In the treatment of infections due to Corynebacterium minutissimum.
Extraenteric amebiasis requires treatment with other agents.
Acute pelvic inflammatory disease caused by Neisseria gonorrhoeae. Erythromycin lactobionate for injection, USP followed by erythromycin base orally, as an alternative drug in treatment of acute inflammatory disease caused by N gonorrhoeae in female patients with a history of sensitivity to penicillin. Primary syphilis caused by Treponema pallidum. In treatment of primary syphilis, spinal fluid should be examined before treatment and as party of the follow-up after therapy. When tetracyclines are contraindicated or not tolerated, erythromycin is indicated for the treatment of uncomplicated urethral, endocervical, or rectal infections in adults due to Chlamydia trachomatis.