Epidemiology Lymphoma cases occur in all kinds of people, yet some types of lymphoma are specific to a certain age range or gender. The HTLV-1 retrovirus is associated with some types of lymphoma as well. Secondary NHL's may result from earlier chemotherapy or radiation. Immunodeficiency Immunosuppression and autoimmune diseases are linked to some lymphoma types . HIV-1 and congenital immunodeficiniesare associated with a poor prognosis and high grade lymphomas.
Immunosuppression following transplantation also increases risk.
Age Overall lymphoma occurs more in older people, but different histopathologic subtypes are diagnosed with higher frequency in a given age group.