The small and large intestines are very susceptible to effects from cancer drugs because the cells of the intestine are rapidly dividing. Chemotherapy can interfere with the normal growth of these cells, so they can't carry out their normal functions. The cancer itself can also disrupt the normal function of the bowels. Tumors can make hormones or substances that can change the absorption and elimination patterns of the intestines. Stress, antibiotics, and some foods or nutritional supplements can also cause diarrhea.
Fever can be present along with diarrhea.
The combination of fever and diarrhea is serious, because it can be a sign of infection. Report this to your doctor or nurse immediately. Important Early notice and treatment of diarrhea will allow for dose adjustments that may be appropriate to optimize your cancer care. It is in your best interest to alert your doctor or nurse to any signs of diarrhea or fever. These can all make you uncomfortable and can be a cause for medical concern.