Consider transfer of any patient with progressive hepatic dysfunction to a facility that has a liver transplant service. Liver failure is the most serious complication of amatoxin ingestion. Hepatic coma and hypoglycemia can complicate liver failure. Progressive hepatic failure can lead to hepatorenal syndrome. With good supportive care, mortality rates are now lower than in the past.
Liver transplant can save the life of a patient with the most severe amatoxin poisoning.
Treatment of human amatoxin mushroom poisoning. Myths and advances in therapy. Poisoning due to amatoxin-containing Lepiota species. Amatoxin poisoning in northern California, 1982-1983. Medicine is a constantly changing science and not all therapies are clearly established.