Avoid breathing vapors, keep upwind. Irritant- inhalation, skin, eye. Central nervous system depressant. Poisoning may affect the liver and kidneys. Persons with preexisting skin, liver, kidney, or chronic respiratory diseases.
Gastroenteric absorption is enhanced by the presence of fats or oils.
Alcohol may enhance the toxic effects. 1000 ppm Immediately Dangerous to Life or Health. At higher concentrations, central nervous system depression with headache, dizziness, drowsiness, somnolence, transient anesthesia and incoherence, cyanosis from methemoglobinemia, spastic contractions of the extremities, rapid respiration, weak and irregular pulse, burgundy-red urine, loss of consciousness, coma, and respiratory and circulatory collapse may occur. 8000 ppm produced severe narcosis after 30 minutes and death within 2 hours after removal from exposure. Pathological changes may include hypertrophy and necrosis of the liver and bronchial epithelium of the lungs, edema of the brain and submucosal hemorrhage in the stomach.