It depends on the prakruthi of the parents and the state of their mind at the time of conception, etc. If one dosha is predominant in a person, then that imbalance results in certain kinds of susceptibilities. It can be aggravated by improper habits and diet. These can be treated by medication. The second possibility for falling ill, according to ayurveda, cannot be analyzed on material terms.
Karmic diseases require atonement or some qualitative change from within.
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