Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. AIDS Treat News. Educating patients who use protease inhibitors is essential. Another concern is that improper use of these drugs may cause viral resistance, which would decrease future effectiveness in all patients. Both indinavir and ritonavir seem most effective when used in combination with other drugs.
Further study is needed to determine which combinations and dosages are most effective.
Patients are urged to delay protease inhibitor therapy until more information is available on safety and effectiveness. National Library of Medicine. Always watch for outdated information. This article first appeared in 1996. This material is designed to support, not replace, the relationship that exists between you and your doctor.