Professionals should be aware that TS can be an alternative to sexual abuse as an explanation of such behaviors. SIDS has been repeatedly linked to the presence of prolonged sleep apnea and defective arousal mechanisms. Multiple cases of SIDS may occur in some families, and siblings of SIDS infants are at a 3 to 10 times greater risk of SIDS than the general population. This suggests genetic factors can play a role. All probands and many relatives were personally interviewed.
Dopamine plays a major role in the regulation of appetite and growth hormone.
Dopaminergic agonists suppress appetite and dopamine D2 receptor antagonists enhance it. We examined the hypothesis that allelic variants of the DRD2 locus may be associated with weight and height. Two separate sets of subjects were studied and these results were significant for both, providing an internal replication. Genetic factors in substance abuse based on studies of Tourette syndrome and ADHD probands and relatives. I. Drug abuse .