Please conduct a current literature search and check the appropriate current online database for the most recent quantitative information. Erythema, coughing, pulmonary edema, and necrosis may also occur and, at extremely high concentrations, respiratory paralysis and death. No information is available on the reproductive or developmental effects of acetaldehyde in humans.
Human data regarding the carcinogenic effects of acetaldehyde are inadequate.
An increased incidence of nasal tumors in rats and laryngeal tumors in hamsters has been observed following inhalation exposure to acetaldehyde. Exceedance of the RfC does not imply that an adverse health effect would necessarily occur. As the amount and frequency of exposures exceeding the RfC increase, the probability of adverse health effects also increases. It is an intermediate product of higher plant respiration and formed as a product of incomplete wood combustion in fireplaces and woodstoves, coffee roasting, burning of tobacco, vehicle exhaust fumes, and coal refining and waste processing. Hence, many individuals are exposed to acetaldehyde by breathing ambient air.