Nonbacterial endocarditis, usually with neoplasm or severe infection, can produce transient ischemic attacks and focal ischemic stroke. Rapid onset of headache, fever, stiff neck, and photophobia may be associated with a CSF mononuclear pleocytosis, elevated proteins, slightly depressed glucose, and consistently negative cytologic studies and cultures. The episodes are transient but can be recurrent. Myopathy similar to polymyositis may complicate AIDS or zidovudine therapy. A few patients present with renal insufficiency or nephrotic syndrome, with symptomatic anemia, or with immune-mediated thrombocytopenia.
Every drug has certain effects and possible side-effects that vary significantly in each individual.
Patterns of specific opportunists vary both geographically and between risk groups. Recently the incidence of KS has been diminishing. Toxoplasmosis and TB are more common in tropical areas where the prevalence of latent infections with Toxoplasma gondii and Mycobacterium tuberculosis in the general population is high. Headache, lethargy, confusion, seizures, and focal signs evolve over days to weeks. CT findings include ring-enhancing lesions with a predilection for basal ganglia.