Methods for evaluating genetic factors, tobacco, alcohol, radiation, chemicals, pharmaceuticals, viruses and nutrition will be reviewed in lectures and by classroom discussion of selected publications. May be elected more than once for a maximum of six credits. Election for dissertation work by doctoral students not yet admitted to status as candidate. Election for dissertation work by doctoral students who have been admitted to status as candidate. This course will cover a broad range of subjects relating to cancer biology.
Emphasis is on the relationship between basic science and clinical aspects of cancer.
Topics to be covered include carcinogenesis, cancer progression, tumor pathology, oncogenes, cellular growth control, tumor suppressor genes, oncogenic viruses, apoptosis, tumor immunology, clinical oncology, and therapeutics. The course consists of lectures by faculty in the Cancer Center who are experts on various topics. This course explores the relationship between environmental chemical exposures and adverse health consequences, examining factors that determine the influence toxicity, such as chemical dose and structure, metabolism, and the age and genetic make-up of the individual. The role of chemical exposures in the etiology of specific diseases, such as cancer, birth defects, and neurological disorders, is described. The assessment of risk to human health from chemicals is discussed.