The following healthcare information is provided by the Alpha One Foundation.
Further information is available by visiting their website.
When AAT levels are low, the body is no longer protected from an enzyme in the white blood cells that can cause damage to the air sacs in the lungs. AAT Deficiency is an inherited genetic disorder resulting in low levels of AAT or none at all. AAT Deficiency causes lung disease in adults, particularly in the presence of cigarette smoking and dirty air environments. AAT Deficiency may cause progressive liver damage in adults, children and infants. AAT Deficiency is often underdiagnosed.