Do not store in the bathroom, near the kitchen sink, or in other damp places. Heat or moisture may cause the medicine to break down. Do not keep outdated medicine or medicine no longer needed. Be sure that any discarded medicine is out of the reach of children. These may be early warning signs of more serious skin or related problems that could develop later .
Malaria is spread by mosquitoes.
Wear long-sleeved shirts or blouses and long trousers to protect your arms and legs, especially from dusk through dawn when mosquitoes are out. Apply mosquito repellant to uncovered areas of the skin from dusk through dawn when mosquitoes are out. This medicine may cause blood problems, especially if it is taken for a long time. If so, it is important to take the leucovorin every day while you are taking this medicine. Do not miss any doses.