Neurotransmitters are electro-biochemical agents that cross nerve synapses. They are the vehicles that carry information back and forth between your body and mind. Much of our mental and physical sense of continuity and security depends upon our ability to repeat appropriate and predictable actions. Neurotransmitters normally inform muscles constantly about what they're doing, so their actions can be modified. Much of our muscle tension function is improperly controlled by these neurotransmitters.
Healthy people think nothing of picking up a glass of water and bringing it to their lips.
They know just how tightly their hand has to grip, how heavy the glass of water feels, and how much speed is appropriate to accomplish this act smoothly. The thumb grasps with too little pressure, and the wrist muscle lets go when flexed. The economy of effort is not there. To enable us to sit , walk, and stand, the entire musculature must be able to feel its own activity, and we often can't do that. During a flare, current symptoms become more intense, and new symptoms frequently develop.