Please conduct a current literature search and check the appropriate current online database for the most recent quantitative information. Animal studies have reported reduced fertility, and neurological effects in the offspring of animals treated with chlordane.
Human studies are inconclusive regarding chlordane and cancer.
Animal studies have reported liver cancer in mice and male rats exposed to chlordane via ingestion. Exceedance of the RfD or RfC does not imply that an adverse health effect would necessarily occur. As the amount and frequency of exposures exceeding the RfD or RfC increase, the probability of adverse health effects also increases. Currently, exposure to chlordane appears to be highest for those persons living in homes that were treated for termites with chlordane. Chlordane remains in the food supply today because much of the farmland in the United States was treated with chlordane in the 1960s and 1970s, and it remains in the soil for over 20 years.