ATM also are involved in DNA repair. The objective of the IBT studies at cellular and molecular levels is to provide data that can be translated quickly to the bedside of cancer patients, through collaborations with clinical researchers at the Health Science Center. DNA, found in the cells of living things and containing the genetic blueprint, takes a constant beating from harmful agents in the environment. Our DNA is repaired. But sometimes, the fix-it mechanism is impaired or doesn t work.
Genetic damage progresses, resulting in undesirable conditions such as cancer.
Early detection of cancer greatly impacts patient outcomes. Many researchers at the Health Science Center have made contributions in this area, including Michael Sarosdy, MD, professor of surgery and chief of the urology division. He headed a U.S. multicenter study that found a new test improves detection of recurrent bladder cancer over the standard non-invasive method. The new test provides positive or negative results in five minutes. More than 50,000 Americans are diagnosed with bladder cancer each year.