Integrin mediated sensory contact. Interference reflection image of a T cell contact with a serum coated supported planar bilayer. Image is shown in real time. Contact area dynamics in immunological synapse. Note membrane ruffling at the periphery of the immunological synapse.
Image is shown in real time.
Images captured with Cenk Sumen. Contact area dynamics triggered by TCR engagement alone. T cell reacting with planar bilayer containing MHC-peptide complex only. The contact has a dynamic and lacy appearance. Image is shown in real time.