Intracutaneous triamcinolone acetonide injection may lead to rapid and lasting control, although monthly retreatment is often necessary. Avoiding the sun with opaque blocks is essential. The most effective treatment is a combination of Chloroquine 65 mg, Atabrine 25 mg, and Plaquenil 50 mg, called Triquin. Dosage varies from six to one daily, usually three times a day initially, dropping to as low a maintenance dose as can be found later. Other methods of treatment include gold sodium thiosulfate given intravenously starting at 5 mg and increasing to 50 mg weekly for 6-10 weeks.
Histopathologic changes are roughly the same for all forms of lupus erythematosus.
Polymorphic Light Eruption. There is arguably a sixth type of pigmented mole, the protuberant polypoid papilloma, which is usually flaccid with a narrow stalk and most often located in the axilla and groin. Often actually a fibroma, this occasionally contains nevus cells and so should be classified with the moles. The decision as to which moles should be excised completely, which should be removed with a superficial cosmetically acceptable result, which should be left alone and which should have a small excisional biopsy can be made by physicians only after many years of experience looking at moles and their microscopic tissue. In general, when in doubt, perform a biopsy.