In the drug management of depressive illness. Amitriptyline may be used in depressive illness of psychotic or endogenous nature and in selected patients with neurotic depression.
Endogenous depression is more likely to be alleviated than are other depressive states.
Amitriptyline, because of its sedative action, is also of value in alleviating the anxiety component of depression. As with other tricyclic antidepressants, amitriptyline may precipitate hypomanic episodes in patients with bipolar depression. These drugs are not indicated in mild depressive states and depressive reactions. Contraindications In patients who have shown prior hypersensitivity to it. It should not be given concomitantly with a MAO inhibiting compound.