I feel alone in this. Isolation is a common feeling among people with a chronic disease. The antidote to isolation is activities, physical or social, which increase energy and the possibility for better coping. The chemistries of the brain require activity of the body to deal with mood problems. They are the result of exercise and contact with people.
Introverts seem to be okay with isolation as long as they can contemplate ideas.
Chatters mentioned using meditation and massage therapy. Several said they try to stay busy. That helps when things are not too bad. Another uses guided imagery, aided by an audio tape. Life in general is difficult.