The importance of the Lamprey River to the towns of Lee and Durham is reflected in the planning efforts of both towns. The Durham Master Plan identifies the river as an important resource. In Lee, a shoreland protection ordinance prevents construction within 100 feet of the river and prohibits the removal of more than 50 percent of the basal area of trees along the river. Recreational Resources a. Canoeing is a popular activity on the Lamprey River.
Fishing continues into the winter, with ice-fishing popular along the length of the segment.
Salmon Unlimited has negotiated agreements with private landowners along key areas of the river segment to allow access for fishermen. Swimming, tubing, horseback riding, bird watching, and camping are other recreational activities that people enjoy on or next to the Lamprey River. The privately-owned Durham Boat Company offers instruction, storage, and launching facilities for sculling shells below Moat Island. Three campgrounds located in the river segment have facilities for seasonal camping. Both the Lee and Durham Boards of Selectmen and Conservation Commissions have voted to support the designation.