Placement of deep brain stimulators causes inactivation of subthalamic nucleus. Deep brain stimulators are adjustable allowing for maximum benefit and minimal side-effects.
Early results are very promising.
STN is a small nucleus requiring advanced imaging and neurophysiologic techniques for optimal localization. Localization of STN Patients first undergo stereotactic localization using MRI and CT imaging to optimize localization. The optimal location is confirmed by recording the activity of single neurons using an array of micro-electrodes. Electrodes are advanced using a specialized microdrive. Signal is displayed on a computer monitor and, as and audio signal.