The embryo transfer is typically carried out on the third, fourth or fifth day of progesterone therapy. Estrogen and progesterone then need to be continued for approximately eight weeks following the transfer. In our program, we use Lupron .5 mg.subcutaneously starting in the mid-luteal phase. Our preferential estrogen is micronized estradiol which is given starting in 2-4 mg. 400 mg. twice a day.
Embryo transfer is carried out on the third or fourth day of progesterone therapy.
If the surge occurs that day or on the preceding or following day, then the fresh transfer can successfully occur. If the surge occurs outside that time interval, then all embryos can be frozen for use in a subsequent cycle. For a frozen embryo transfer cycle in a normal cycling woman under the age of forty, an unmedicated or minimally medicated cycle can be used. In our program, in a frozen embryo transfer cycle we do the embryo transfer three days following a spontaneous LH mid-cycle surge. We also use supplemental vaginal progesterone capsules 200 mg. twice daily starting the day before the transfer.