Same as other chronic inflammatory reactions 5. Sequelae of Granulomatous Inflammation Destruction of the inciting stimulus with resolution of inflammation and repair of the tissue. Persistence of the inciting stimulus and persistence or progression of the inflammatory process and disease. Process by which lost or necrotic cells are replaced by vital cells. Process resulting in an increase of collagen in tissue.
Fibrosis is often an important, and sometimes necessary component of the repair process.
Highly organized fibrovascular tissue that often replaces necrotic debris and areas where poor regeneration occurs. B. Tissue Repair Mechanisms a. Tissue Capacity for Parenchymal Regeneration Tissues vary in their ability to mount an effective repair process that returns tissue function to pre-injury levels. Cells with latent capacity to regenerate. Cells are normally in G0 state. The have long life spans and do not turnover quickly.