A tube may be needed when the face is directly injured or swelling in the throat threatens breathing. If breathing is normal, oxygen given through a face mask may be all that's needed. The bandages are usually changed two or three times a day. Because extensive burns are extremely susceptible to severe infections, antibiotics may be given intravenously. A tetanus booster may also be given, depending on the person's previous immunizations.
Extensive burns can lead to a life-threatening loss of body fluids.
Therefore, fluids are given intravenously to replace those lost. Deep burns can cause myoglobulinuria, a condition in which the protein myoglobulin is released from damaged muscles and damages the kidneys. Kidney failure may follow unless sufficient fluids are replaced. Burned skin develops a thick, crusty surface called eschar, which can become taut and restrict blood flow to the area. Restricted blood flow can be dangerous if the burn completely surrounds an arm or a leg.