Sometimes AIDS organizations or health departments will give you condoms for free. If you are using drugs, try to buy from a reliable supplier whose goods you like or your friends have tried. Don't be afraid to ask your dealer what their drugs are cut with and what you can expect to experience when taking them. For example, sometimes what is sold as e contains a combination of a variety of drugs, and very little of the MDMA that gives e its reputation. Avoid mixing drugs, including alcohol and club drugs.
Drug interactions can increase harmful side effects.
For example, you should avoid mixing GHB with downers, especially alcohol, which increases the likelihood that you will overdose. Don't mix poppers and Viagra. This can reduce your blood pressure to fatal levels. Avoid mixing Viagra with ecstasy. If you do, try half the normal amount of each.