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Ion channels allow selected ions to cross lipid bilayer membranes.
They are central to the properties of excitable cells such as neurones, and are targets for local anaesthetics and related drug molecules. Molecular modelling and simulation studies are being employed to probe the relationship between ion channel structure and function. Simulations of Ion Channels. Trends in Biochemistry Vol. Structural and functional studies on proteins involved in innate immunity, their interactions with infectious microorganisms and alterations in the proteins in disease.