Babies born to mothers who abuse depressants during pregnancy may be physically dependent on the drugs and show withdrawal symptoms shortly after they are born. In addition, users may perspire, experience headache, blurred vision, dizzyness, sleeplessness, and anxiety . Extrememly high doses can cause rapid or irregular heartbeat, tremeors, loss of coordination, and even physical collapse. An amphetamine injection creates a sudden increase in blood pressure that can result in stroke, very high fever, or heart failure. In addition to these physical effects, users report feeling restless, anxious, and moody.
Higher doses intensify the effects.
Persons who use large amounts of amphetamines over a long period of time can develop an amphetamine psychosis that includes hallucinations, delusions , and paranoia. These symptoms usually disappear when drug use ceases. Many popular commercial preparations such as paint thinners and cleaning fluids are mixtures of volatile substances making it difficult to be specific about their various effects. Immediate negative effects of inhalants may include nausea, sneezing, coughing , nose bleeds, fatigue, lack of coordination, and loss of appetite. Solvents and aerosol sprays may also decrease the heart and respiratory rates and impair judgement.