It's a good idea to register with your embassy or consulate if you are traveling in an unpredictable place. Buy travel insurance . If there is any place where it could come in real handy, it's Africa. If you are going on a tour or safari with a company from home, check with them for travel insurance. Pack light .
Distances are great in Africa and clothes and other essentials are cheap.
If you don't think you really need it, don't bring it. Bring sunscreen . The African sun is notoriously strong. Don't underestimate its power. Bring something to donate .