However, fever, fatigue, loss of appetite and swollen glands are also common features of mono. Because the clinical symptoms of mononucleosis are similar to those of many other diseases, your practitioner will use several laboratory tests to confirm the diagnosis of mono. These tests check for the presence of specific antibodies that appear in the blood of persons with mono. The mono test may not be positive at the early onset of the disease. The usual duration of symptoms is 2-3 weeks.
Many cases are so mild that some people recover without knowing they have had mono.
In mild cases you may be able to go about your usual activities. If symptoms are severe, bed rest may be necessary for a few days. Complications such as persistent fever or jaundice may prolong your recovery. Some weakness and tiredness may persist up to two months after the acute symptoms disappear. Extra rest is needed for fatigue.