The people in it do not look Japanese. Where the biggest round or oval glare is, is not always where the pupil is. If the character is not Japanese, the eye color may be something within the relm of the race of the character.
Many characters have a nose that looks like a stubby beak.
Lots of times in a head-on view, the nose is only a small dot or no nose at all. Some characters are drawn with a nose that does look 'real'. With some expressions, the mouth is very big, but still keeps the cuteness unless it is meant to be something different. In most cases the hair is drawn with streaks of light reflection or shimmering. If the character is not Japanese, the hair color may be something within the realm of the race of the character.