Nausea and vomiting can accompany these effects, as well as constipation. Users find themselves midway between awake and asleep. Heroin also decreases sexual performance. This happens because heroin affect the release of many hormones and neurotransmitters, including those associated with regulating sexual behavior. Ability to reach orgasm is often impaired.
Eyelids are droopy, perhaps slowly closing periodically as the person nods off.
Irises may be red. Heart rate and blood pressure are normal. Respiratory rate is very slow. Skin complexion may be flushed or pale. Numbness to pain.