Proctosigmoidoscopy for advanced cases. The cancer is confirmed by a vaginal biopsy. N2 indicates groin node metastases on both sides. Several factors are considered in choosing the most appropriate way to manage vaginal cancer, including the cell type, stage, size, location of the lesion, presence or absence of the uterus and whether the woman has had previous radiation to the pelvis. Early carcinomas are generally treated with either surgery or radiation therapy and chemotherapy.
External radiation is given in divided doses to the pelvis five days a week for five weeks.
Advanced cancers are treated with radiation therapy with simultaneous administration of combination chemotherapy. TNM Tis, N0, M0 Carcinoma in situ or intraepithelial carcinoma. The tumor may also be treated with laser therapy, intravaginal chemotherapy with 5-fluorouracil cream or intracavitary radiation. Five-Year Survival 100 percent. The carcinoma is limited to the vaginal wall.