Surgery may be necessary for the RVT of renal cell cancer, particularly for cure of malignancy. Many nephrologists recommend normal protein intake for patients with nephrotic syndrome. The current standard is ACE inhibition. The indicators for thrombolysis in the setting of RVT are unclear. There is no data available comparing thrombolytic therapy to anticoagulation.
Interactions Note that coumadin is unsafe in pregnancy.
The primary abnormality in nephrotic syndrome is excessive urinary protein loss. Urinary protein per se is injurious to the renal tubules. ACE inhibitors and angiotensin II receptor blockers decrease urine protein through an effect on efferent arteriolar pressure. Should be titrated to as high a dose as tolerated. If protein loss decreases, hypercoagulability improves.