Here s the cecum and the appendix. You can see intense narrowing here with dilatation in between due to inflammation and possibly fibrosis in the bowel wall. This is fistula formation. This is aortoenteric fistula in Crohn s disease where a There are complications of inflammatory bowel disease related to chronic inflammation, and the systemic complications are glomerulonephritis and amyloidosis related to the elevated inflammatory proteins and immune complexes. This is relatively uncommon now that we have better treatments.
Local complications are still common.
Anal disease particularly with chronic anusitis, fissures, fistulae, abscess and strictures, and in the bowel, stricturing, sinuses and fistulae. And also inflammatory tissue associated with the bowel. The only curative therapy is surgical and that s only for ulcerative colitis. If you look at medical therapy, we certainly If you look at the 5- ASA drugs, sulfasalazine is the mainstay that has been with us for many years, and the cheapest. It s an oral formulation.