Figure shows a 3-D whole cryosection macaque brain consisting of a 640 x 480 x 200 voxel volume. Data are taken from David Van Essen laboratory in the Department of Anatomy and Neurobiology at Washington University. The Hierarchical approach is linked to the Biological problem itself, coming out of the various kinds of information that is provided by the anatomists. The algorithm is driven by these sub-manifolds. We follow the approach that the highest dimensional transformation is a result from the solution of a sequence of lower dimensional problems driven by successive refinements or partitions of the images into various Biologically meaningful sub-structures.
Figure shows two whole brains that have the gyri and associated sulci labeled.
The sulci are examples of 1 dimensional sub-manifolds in the Brain. The mammalian cerebral cortex has the form of a layered, highly convoluted thin shell of grey matter surrounding white matter. A cryosection image from a Macaque monkey is shown below. The cortical mantle consisting of the highly convoluted thin shell of grey matter surrounding white matter is one of the most striking features of the brain and it plays a tremendously important role in understanding brain functions. Although the cortical surface is such an important feature of the mamilian brain, the precise geometry and variability of the cortical surface are little understood.