45 micron filter under vacuum. Continue to draw a vacuum for an additional five minutes. Equilibrate to 37 'C and use immediately. Sampling Precisely 30 minutes after tablet has been dropped, sample from the USP-designated area. Filter both samples and standards.
Documentation Document each step in a lab notebook or binder.
Photocopy any thermal printer paper and tape both original and photo copy in notebook. Record all serial numbers and lot numbers. All rights reserved. Copyright 2001, Varian, Inc.