In this study the only factors associated with ulcer recurrence were H. pylori infection and continued use of nonsteroidal anti-inflammatory drugs. Triple therapy for eradication of H. pylori is not without its problems. This would include those with frequent recurrences, and who would need maintenance treatment with H2-antagonists or proton pump inhibitors. It would also include those being considered for elective surgery and those who have bled or perforated in the past. Forbes et al.
Maintenance therapy is used in patients with a history of recurrence.
Patients treated to eradicate H. pylori will suffer many fewer episodes of recurrence. Overall cost should be lower. This is likely to increase effectiveness. This is likely to reduce costs. Will decrease total cost of care for this problem.