That means we'll have to assemble the interplanetary craft in space. Perhaps we could use capsules bound together and hauled to Mars using a kind of space-tugboat kind of arrangement. The change in gravity will affect every day life in many ways. Simple walking will be slowed to about sixty percent the speed on earth and about half as many calories will be lost in the process as would be on earth. This means less food would be required to maintain the average weight.
Gravity is only one change.
The thin atmosphere allows temperature and pressure to fluctuate widely. Despite the ease of change, weather patterns tend to be rather uniform. The lack of an ionosphere makes radio transmissions limited even thought there are few topographical intrusions. Initially, the first Mars colonists will live in their landing craft. The colony should probably be entrenched into the surface to protect it until a sufficient atmosphere exists.