In addition, glucose metabolism is critical for optimal exercise performance by healthy individuals. Exercise and diet can fundamentally alter glucose metabolism, and skeletal muscle is a pivotal tissue for glucose homeostasis. We have demonstrated that either a single bout of exercise or a brief period of reduced caloric intake can substantially enhance insulin-stimulated glucose transport of skeletal muscle. We are also conducting experiments aimed at identifying the mechanisms which underlie the enhanced glucose transport following muscle contractile activity. Emphasis Group Exercise Physiology University Affiliations Interdepartmental Graduate Program in Nutritional Sciences Institute on Aging Representative Publications Cartee, G.D. and J.O. Holloszy.
Exercise increases susceptibility of muscle glucose transport to activation by various stimuli.
American Journal of Physiology. Douen, A.G., T. Ramlal, S. Rastogi, P.J. Bilan, G.D. Cartee, M. Vranic, J.O. Holloszy and A. Klip. Journal of Biological Chemistry. Cartee, G.D., C. Briggs-Tung, and E.W. Kietzke. Persistent effect of exercise on glucose transport across the lifespan.