A high level increases risk of infection and side effects. A low level invites organ rejection. Do not take cyclosporine the morning of your clinic visit. With Cyclosporine I do not include drugs which may alter your blood levels of cyclosporine if taken. This is not a complete list.
Drug interactions are no longer a minor matter for the heart transplant recipient.
You must never take any drug or over the counter medicine without checking first with your transplant cardiologist. Methylprednisolone Metoclopramide Naproxen Nicardipine Nifedipine Ranitidine Sulfamethoxazole Trimethoprim Sulindac Tacrolimus Vancomycin Sexuality, Children and Other Notes Cyclosporine is transformed in your body into about 15 metabolites. The drug is eliminated through the liver. Cyclosporine's half-life is about 18 hours. This is radically different from one patient to the next, though.