He noted that it is important always to explain the warning signs of an infection to the patient. The wound should also be checked for proper healing one week later when sutures are removed Other local cosmetic treatments for KS performed in the clinic include freezing lesions with liquid nitrogen for about 30 seconds. But if the lesion is not adequately frozen, there's a possibility that active KS at the periphery of the lesion will remain. Often a treatment or two will be enough to completely flatten and whiten the KS lesion. Another danger, in dark-skinned patients, is hypopigmentation.
Intralesional chemotherapy is also a treatment for such lesions.
Intralesional chemotherapy may be useful to treat oral lesions, for example on the gum, particularly in patients who wish to avoid systemic chemotherapy or have no significant disease elsewhere. Dr. Farthing said that lesions may need intermittent retreatment. If an excision biopsy is performed, the lesion can be divided for the same purpose. The clinician should request a silver stain if suspicious of syphilis, or a Warthin-Starry silver stain if suspicious of bacillary angiomatosis. If a large piece of tissue is desired, Dr. Farthing advised an elliptical biopsy that cuts through the center and the active edge of a lesion and out into normal skin.