It's transmitted to all warm-blooded animals, including humans, mainly through the bite of an infected animal. Infected dogs may withdraw and avoid contact with people or become unnaturally aggressive. Once clinical signs appear, death always occurs. All states have laws that require vaccination against rabies to protect both pets and their owners. Signs of infection include sudden lameness , evidence of severe pain, swollen joints, depression and a total reluctance to move.
Incidence varies by geographic region.
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