Clinical signs include polyuria, polydipsia and glucosuria initially with metabolic acidosis and progression to renal failure leading to death occuring later. Progession occurs over months to years. Familial renal disease in the dog and cat. Juvenile Renal Disease and Juvenile Renal Disease in Standard Poodles by Susan L Fleisher are written by a lay person but are well referenced. Ectopic ureters are a congenital defect in which the ureters empty urine into another location, other than the bladder.
Ectopic ureters occur more commonly in females.
There is a familial tendencyfor ectopic ureters in Siberian Huskies and Black Labradors. There are a few reported cases in cats. Ectopic ureters are often associated with other congenital anomalies or associated diseases such as mega-ureter due to urine reflux, decreased kidney size, congenital hypoplasia, chronic pyelonephritis, decreased bladder size, either congenital or from disuse if ectopia is bilateral. Clinical signs include urinary incontinence present from birth. Animals can void normally if only one ureter is ectopic.