The molecular electronics machine needs only enough intelligence to be able to report information to the outside world. An outside rather conventional computer, the doctor, then diagnosis and treats the patient by down loading configuration bits. Similarly, we construct these machines, not by self-assembly, but by downloading a carefully computed set of configuration bits, which place and route the machine. Such algorithms may be even better in the long run than those discovered by evolution. To some extent evolution finds itself in a cul de sac, having invented a mechanism which always produces large complex organisms from a single cell.
Life is stuck with that model.
All the information needed to create the organism has to be packed into that one cell. We need not be constrained to such a model in constructing amorphous computers. Amorphous machines need not be autonomous. Our defect tolerant molecular electronics takes advantage of reconfiguration by first creating special purpose computer to find defects, and then reconfiguring to make the end users computer. Having found the defects, we could create a special purpose machine to find the connectivity of the amorphous computer.