These compounds are barely soluble in water. Even when administered orally, TPD and TTFD produce a higher thiamin level in the blood than thiamin hydrochloride. If beriberi occurs in a breastfeeding infant, both the mother and child should be treated with thiamin. Neuromuscular agents may enhance effects of thiamin. IV dextrose solutions and high carbohydrate diets may increase thiamin requirement.
Heart rate reduces.
Respiratory rate reduces. Diuresis and reduction in heart size may be apparent within 1-2 days. In cases of dry beriberi and Korsakoff psychosis, the complete resolution of the neurologic symptoms can take several months. Vitamin Deficiencies and Excesses. Nelson Textbook of Pediatrics.