They led an investigation that identified and characterized the FHIT gene, which can lead to colon, stomach, esophageal and lung cancers when abnormal. The discovery of the FHIT gene may make it possible to identify people predisposed to certain cancers and to develop new drugs that may arrest the growth of cancer cells. Isolating the Causes of Obesity Researchers created a blood test that can determine a person's leptin level. Data indicates that obese people have higher levels of leptin than lean persons, yet the hormone is the same in both. The finding suggests that a defect in how the leptin signal is processed may hold the secret to obesity.
Further studies are under way.
Statewide Jefferson's Center for Research in Medical Education and Health Care is developing a statewide system to track the career outcomes of students in Pennsylvania's eight medical schools. The database also will measure the effect of the revised curriculum on student preparedness. Expanding Educational Opportunities in Pediatrics Now, Alan R. Spitzer, MD, the Robert L. Brent Professor and Chairman of Jefferson's Department of Pediatrics as well as Pediatrician in Chief at duPont Hospital for Children, shares his time between the two institutions. A preceptorship program for residents contributes to the growth of the institutions' primary care network. Two fellows have been selected for a one-year postgraduate program on managed care, funded by U.S. Healthcare.