Ingestion of a toxic dose can cause gastroenteric irritation, narcosis and injury to the kidneys and liver. Aspiration into lungs can produce severe lung damage and is a medical emergency. Other symptoms are expected to parallel inhalation. Vapor concentration of 2,500-3,000 ppm causes minor irritation of eyes, nose and throat. Inhalation of higher concentration may cause headache, nausea, confusion, drowsiness, convulsions and coma.
Higher concentrations can produce central nervous system depression, narcosis, and unconsciousness.
Prolonged exposure to the vapor irritates the skin. Eye contact with acetone is irritating and may be damaging. Acts as an anesthetic in very high concentrations. Headache, nausea, dizziness, and narcosis can result from excessive exposure to vapors. Causes severe eye irritation, experienced as discomfort or pain, excess blinking and tear production, with marked excess redness and swelling of the conjunctiva.