Please keep that in mind as you watch the data unfold. Preliminary Findings Initial data from the TIC database were published in 2000. Anger control problems, sleep difficulties, coprolalia, and self-injurious behavior only reach impressive levels in individuals with comorbidity. Anger control problems are strongly correlated with comorbidity, regardless of site, region, or whether assessed by neurologists or psychiatrists. The mean age at onset of tics is 6.4 years.
Males are more likely to have comorbid disorders than females.
The earlier the age at onset, the greater the likelihood of a positive family history of tics. Because behavioral problems are associated with comorbidity, their presence should dictate a high index of suspicion of the latter, whose treatment may be at least as important as tic reduction. The established database can be used as the entry point for further research when large samples are studied and generalizability of results is important. All Rights Reserved.