There is a slight male predominance. Treatment of causative disorders may prevent development of nephrotic syndrome. A physical examination confirms the symptoms. Symptoms and signs of causative disorders may be present. A urinalysis reveals large amounts of urine protein .
Fats are often also present in the urine.
Treatment goals are to relieve symptoms, to prevent complications, and to retard progressive kidney damage . Treatment of the causative disorder is necessary to control nephrotic syndrome. Treatment may be chronic . Corticosteroid, immunosuppressive, antihypertensive, and diuretic medications may help control symptoms. Antibiotics may be needed to control infections.