A higher power view of an area of dystrophic calcification in skeletal muscle. The black areas point to longitudinal, as well as cross sections of normal striated muscle. The green areas point to two foci of dystrophic calcification in this tissue. The fragmentation of the calcium deposits is due to the fact that as the knife cuts through the tissue, areas of calcification, being hard, tend to fragment.
Dystrophic calcification is a result of tissue necrosis.
Calcium salts get deposited among necrotic cells, resulting in the appearance of white, chalky deposits on gross examination, and purple acellular lesions on routine histology. Secondary to tissue necrosis from any cause. The precise pathogenesis is unknown. It appears that necrotic material needs to stay unresorbed for prolonged periods for dystrophic calcium deposition. Appear at white, chalky streaks in tissue.