Default answer is 'No'. Increasing demands for secession from larger states, eg East Timor. Demands for greater regional self-determination and policy autonomy, increasingly blurring the boundaries between sovereign states and autonomous regions.
Economic theory is obsessed with 'small open economies'.
Actually concerned with relatively small OECD economies such as the Netherlands, Norway etc. International institutions such as the UN and World Bank adopted a threshold of 1m in the 1970s. Even smaller thresholds have been proposed by some specialists. An important concern with any threshold is the problem of exclusion at the margin - the 'tyranny of round numbers'. A significant number of small states are SIDS, but this excludes an important group of small non-island LDCs.