Chicken wire fibrosis. These types of initial fibrosis may resolve with abstention. The recognition of fibrous complication of fatty liver is important because it involves a prognosis poorer than simple uncomplicated fatty liver. Initially it is seen in perivenular region and in foci of necrosis. It progresses to become pericellular and massive in the central area and may cause occlusion of the central veins with production of portal hypertension without cirrhosis.
Fibrosis is accompanied with inflammation.
The extent of necrosis and fibrosisand inflammation correlate with the progression of the liver injury. Fat globules fixed with osmium tetroxide Prognosis of alcoholic fibrosis. Initial fibrosis in maro and micronodualr fatty liverwillresove with alcohol abstension. Severe fibrosis may progress to cirrhosis even without continuation of alcohol consumption. In people that continue to drink the cirrhosis is micronodular and regular with 3-4 mm nodules.