Of the two, Gamma knife would be my first choice. This form of surgery, which involves opening the skull and moving the brain to expose the pituitary area, is rarely done anymore. Side effects run a huge gamut including stroke. This has become the surgical procedure of choice. Of course, there is a risk with any general anesthetic.
Effects can be that many symptoms such as headaches still persist.
In addition, it may not be possible to excise the entire tumor, leaving growth hormone levels high. This procedure is performed by going through incisions made in the nose and behind the upper lip. No visible scars show and pain is just about nil. It may still be necessary to have drug or radiation therapy after a successful surgery. All things considered, transsphenoidal surgery has to be considered the best remedial alternative for continued health and longevity, especially with the prospect that drug and radiation therapies will not be required.