Laxative and diuretics abuse causes alternating constipation and diarrhea, malabsorption of essential nutrients, bowel inflammation, and fluid and electrolyte imbalance. Extreme weight loss is associated with neurological deficits. Extreme weight loss and malnutrition adversely affect mental functions. Other effects include cognitive impairment, psychomotor retardation, attention deficit, inability to concentrate, and apathy. Liver disorders Liver enlargement happens in one third of people with eating disorders.
Inflammatory changes take place and liver enzymes are elevated.
Severe hypoglycemia occurs as liver stores of glucose are depleted. Kidney damage Renal damage leads to an increase in toxins remaining in circulation. Electrolyte balance is disturbed and fluid is depleted. Cardiovascular effects Low blood pressure and slowed heart rate are common among eating disordered people. Electrolyte imbalance and acid-base alterations can lead to arrhythmias, heart attack, and sudden death.