Pitchers having to hit for themselves. Pitchers inept at hitting getting a quicker hook from a close game. The use of the double switch when removing a pitcher from the mound. The need for a deeper bench. A greater emphasis on the running game and moving runners.
Games generally move a bit faster.
Other than those little tidbits, everything's the same. Because of those adjustments, slugger Mark McGwire was a bit skeptical last July when he was traded from Oakland to St. Louis. He quickly realized his home-run swing is welcome in any league, and later signed up for three more years with the Cardinals. I do understand the other side, too, that the DH has allowed some great hitters to play an extra five or 10 years. I don't have any problem with that.