What makes the sound so cool is that it adds another dimension to the guitarist's arsenal of riffs.
Audiences love it.
The sample sounds below are in mp3 format, recorded in mono and sampled at 32KHz to keep the file sizes reasonable for download purposes. You can play them with the free Windows Media Player from Microsoft or other utility. This effect sounds like a cross between a wah and a flanger. This is reminiscent of the intro to a particular Bon Jovi song. You can only get this particular effect with a talkbox.