These problems typically subside as experience is gained with the new devices. This tends to be a technique-related problem. Too little pressure when connecting the ports of the primary and secondary tubing together can cause a loose connection and subsequent leakage. Too much pressure can cause connection damage and leakage. Do not twist the secondary tubing when inserting it and do not grasp the tubing collar during this step.
Finger tighten the secondary tubing collar once the secondary tubing is firmly seated.
Luer-lock syringes are connected directly to the port. To administer drug products that are packaged in pre-filled syringes with fixed needles, an injection cap must be attached to the port. The reduced needle system ports are not self-sealing. This backup can occur when you have not clamped the extension tubing close to the IV site. Clamp as close to the IV site as possible using a positive pressure technique.