Injury prevents the liver from supplying these to the body. Anemia and clotting problems, among other things, can result. The liver metabolizes lipid-soluble drugs and hormones. The above range of possible effects result from the liver's inability to carry out specific biochemical functions. If blood can't get through the liver due to scarring or other blockage, it can't get processed.
Inflammation can follow cholestasis, especially in the gall bladder.
Bilirubin is processed in several different ways before it is excreted from the body. Interference with any part of this pathway can cause jaundice. Depending on what goes wrong in the secretory process, accumulated bilirubin may be conjugated or unconjugated. Pathology in the digestive system is closely related to digestive system function. The stomach has a number of defenses to contain and protect against hydrochloric acid and pepsin that it produces.