The process of identifying a disease by its characteristic signs, symptoms, and laboratory findings. Dosage The determination and regulation of the size, frequency, and amount of an agent or medication. A clinical trial in which neither the medical staff nor the person knows which of several possible therapies the person is receiving. Eligibility Criteria that must be met prior to patient entry onto a study. Estrogen One of the female sex hormones produced mainly by the ovaries.
Males also produce estrogen, but in much smaller quantities.
Estrogen is responsible for the development of the female secondary sex characteristics and also has a major role in the menstrual cycle. Hepatitis Inflammation or swelling of the liver. The process through which a person learns key facts about a clinical trial or research study and then agrees voluntarily to take part or decides against it. This process includes signing a form that describes the benefits and risks that may occur if the person decides to take part. Designed to protect patients who take part in studies, IRBs review and must approve the protocols for all clinical trials funded by the Federal Government.