The cranial crests fuse medially to form an elongated boss, a ridge with a median groove, or paired ridges. Postorbital ridges are instinct or absent. The tympanum is round, smaller than the eye. Background color is gray, dark brown or greenish with small dark blotches and an indistinct median line. Some toads have well defined light lateral strips.
Males have a darker throat and the belly is usually spotted.
The Wyoming toad is morphologically and genetically distinct from other toads. Some say that the event separating the ancestral Wyoming toad from the Manitoba toad was the termination of wisconsinite glaciation some 11,000 years ago. Additional research of the Wyoming toads taxonomy is needed to determine if this toad should be recognized as a full species or subspecies as it is presently. All collections and observations have taken place within 30 miles of Laramie. Up until the early 1970's the Wyoming toad inhabited the flood plains of the Laramie rivers and the margins of ponds in the Laramie Basin.