In recent past steroid therapy is being used for treatment. The purpose of this paper is to illustrate the advantage of intralesional corticosteroid therapy over mutilating surgery for management of central giant cell granuloma and opine a hypothesis on biochemical action of steroids in central giant cell granuloma. Materials and Methods 2 patients who reported to Govt. Biopsy was taken to confirm the diagnosis. Sequential radiographic pictures were taken and radiographic correlation giant cell was studied.
Literature is reviewed to opine on action of steroids in central giant cell granuloma.
The follow up period was 6 months to 1.5 years. There was no recurrence. Complete calcification occurred in one case while partial calcification was found in other, which was operated with least postoperative facial deformity. Conclusion Intralesional corticosteroid injections given prior to surgery for Central giant cell granuloma can avoid the surgical intervention, or the problem of postoperative disfigurement can be overcome to a great extent. Hypothesis of action of steroids in Central giant cell granuloma is also suggested.