Probably involves several brain areas, most frequently the posterior hypothalamus. May be caused by tumors, infection or congenital malformations of the brain. Hyperactivity of the adrenal gland due to hyperplasia or tumor, or simple hypterophy without demonstrable pathological lesions. Includes intersitial cell tumors of testis, granuolosa cell tumors of ovary and other ovarian tumors. Pubic hair grows with male pattern.
Hair appears in axilla, on chest, around anus.
Genital Changes Vagina and uterus increase in size and thickness. Uterine blood flow and uterine muscle activity increase. Major and minor labia enlarge and become pigmented. Under the influence of estrogens mainly , breasts enlarge and acquires adult contours.