YAG may be utilized. Untreated lesions persist and become more noticeable after prolonged sun exposure because of darkening. Retinoid - Application of tretinoin has been reported to be successful in some individuals with these lesions. Alters maturation and differentiation of keratinocytes. Has been used for a variety of conditions including flat warts, abnormalities of keratinization, and other keratoses.
Lesions tend to persist throughout life and become more prominent following prolonged sun exposure.
A forme fruste of Darier disease may be impossible to differentiate from acrokeratosis verruciformis of Hopf on clinical grounds. It is important to look for dyskeratosis histologically, which favors a diagnosis of Darier disease. Occurrence of two rare inherited autosomal dominant conditions in the same patient. A followup study. Acrokeratosis verruciformis of Hopf.