Abnormal blood vessels can damage vision by bleeding and scarring. An ICG angiogram can sometimes locate abnormal choroidal vessels better than a fluorescein angiogram. Although they are not known to cause birth defects, fluorescein and ICG should be used with caution in pregnant women. Mild allergic reactions such as skin rash and itching are uncommon, and may be treated with oral or injectable antihistamines. Some individuals may experience slight nausea during the procedure, but this usually passes within a few seconds.
ICG dye contains iodine.
Severe allergic reactions are possible in people who are allergic to iodine. You must inform your ophthalmologist if you think you may be allergic to compounds that contain iodine, including X-ray dyes and shellfish.