If this means that people and objects in the room are no longer on the floor, well, then they find the new floor in a hurry. Occasionally, the wand will also roll the room 180 degrees on the vertical axis, effectively switching floor and ceiling. Doors are useless unless aligned with a corresponding passage in the original wall. Floor stays level. Room rotates on the vertical axis.
Floor is now a wall.
Room rotates on the diagonal. Everything falls to a corner. Floor is now ceiling. All items not bolted down are about to take a trip. Nevvitz was prone to use this wand at late-night parties in large castles, where the damage was not quite so noticeable from normal party damage and where the occupants of the room were drunk enough that they found it amusing as well as painful.