By dissolving the intercellular cement substance salicylic acid produces desquamation of the horny layer of skin, while not affecting structure of viable epidermis. Hydrate skin and enhance effects of medication by soaking affected area in warm water for 5 min prior to use. Remove any loose tissue with brush, washcloth, or emery board and dry thoroughly. Improvement generally should occur in 1-2 wk. Maximum resolution may be expected after 4-6 wk.
Lesions sometimes resolve with treatment of the associated systemic disorder.
A cutaneous marker of hepatocellular carcinoma in South African blacks. Pityriasis rotunda associated with multiple myeloma. Epidermal vitamin A and sunburn in man. Acquired ichthyosis and pityriasis rotunda. Pseudo-ichthyose acquise en taches circulaires.