These enzymes are not glycosylated, do not have a signal peptide, calcium ion content, nor disulfide bridges. Secreted fungal peroxidases. Examples are the lignin and manganese peroxidases from Phanerochaete chysosporium, and Coprinus cinereus p eroxidase. These enzymes have a signal peptide for excretion throught the endoplasmic reticulum, two calcium ions, carbohydrate content and four conserved disulfide bridges. Classical secretory plant peroxidases .
Examples are horseradish, peanut and barley peroxidases.
All enzymes in Classes I-III have an imidazole side chain of a histidine residue as their proximal ligands, and conserved arginine and histidine residues on the distal side of the heme. Pseudomonas aeruginosa cytochrome c peroxidase. There properties are briefly described. The C. fumago enzyme has a thiolate proximal ligand. Also unlike other peroxidases, its distal residue closest to the heme iron is a glutamic acid residue, and it contains a manganese ion.