Intelligence ranges from normal to severe retardation, with most mildly retarded.
While authorities in the genetics of Sotos Syndrome are uncertain about its inheritability, they believe that it is not one disease but a heterogeneous group of disorders, and that it may be either a recessive trait or a new dominant mutation. Most cases of Sotos Syndrome have been sporadic, occurring equally in both sexes. Those afflicted do not seem to have a higher incidence of relatives affected than does the normal population, and the risk of genetic transmission is not known. There have been reports, however, of its occurrence among first cousins, identical twins, and between father and son. Her progress in education and behavior was evident.