It's always difficult to accurately compare pickups since no two guitars are tonally equivalent, and even if you're fast on the swap-out, your ear forgets the subtle nuances. I've had Antiquities in it for about 1.5 years. From what I read, Seymour intentionally winds these at different values so no two sound the same. Due to the quick swap-out, I was able to hear a difference immediately. The Fralin neck pickup has comparable output level but it sounds to me like its resonant frequency is a little higher than the Antiquity, which results in a slight touch less midrange.
Low end seems about the same.
The Antiquity's stronger mids were the most noticeable difference on tape. Again, this is something that a tweak of the amp's tone controls equalizes easily. They certainly don't look like old PAF covers and I always regretted the way they made my Les Paul look. They should be made available with an optional standard nickel cover. So, since I use both clean and overdriven tones, and since I hate the look of the Antiquities' covers, I'll leave the Fralins in my Paul.