This is because there is insufficient evidence that rabies vaccine is effective in wolf hybrids, and hence they cannot be considered immune to rabies even after vaccination. In fact, when high risk exposures occur involving hybrids, they may need to be destroyed for rabies testing. City residents should check with their local animal control for individual city regulations. It is difficult for hybrids to adjust to an environment that is suitable for pet dogs. Natural predatory instincts combined with frustration and insecurity may result in destructive behavior and attacks on children or other animals.
Hybrids are powerful and can destroy furniture, wooden doors, and other large objects.
Only very skilled and very attentive owners manage to keep wolf hybrids healthy and secure. Caring for wolf hybrids also requires specialized facilities. Keeping hybrids on chains is dangerous and walking them in public is not recommended. An unpredictable animal may attack at any time and without provocation. Wolf Park , a nationally recognized authority on the subject of hybrids, stresses the importance of adequate facilities, diet, and commitment by an owner for a wolf hybrid's entire life.