Frequent, urgent, incomplete and uncontrolled urination may occur. Bowel problems include constipation and loss of bowel control. Persons with MS may have difficulty with sexuality and intimacy as evidenced by impotence, diminished arousal, and loss of sensation. There is often an increased sensitivity to heat which can cause a worsening of symptoms. Short term memory, concentration, and judgement or reasoning may also be affected.
Depression is common.
Its course is unpredictable because it can be relatively benign, somewhat disabling, or devastating. At worst, it can leave a person unable to speak walk, or write. From a medical perspective, it is regarded as incurable. There are unpredictable relapses during which new symptoms appear or existing symptoms become more severe. The disease may be inactive for months or years.