The first is normal or bashing damage. This occurs from fists, feet, blunt weapons, and being struck by large heavy objects. Mortals may soak or absorb this damage with their stamina. They roll stamina against Diff 6, with each success removing one point of damage. This kind of damage also heals much faster than the other kinds.
Lethal damage comes from guns, bladed weapons, or other similar types of weapons.
This damage cannot be soaked by mortals. Yes, that includes you Mages and Fae. It also includes ghouls unless they have the discipline of fortitude. Vampires may soak this damage with Stamina and adding fortitude if they have it. Shifters, if we have any, may soak aggravated damage with Stamina.