They have no pallor, no weight loss and no loss of appetite. The severity of fatigue is so overwhelming that they are not able to participate in any activity either at home or at work. Fatigue may be accompanied by a range of physical and psychological symptoms especially myalgia and depression. Because of the normal appearing demeanor, friends, family members, insurance companies and occasionally medical personnel find it hard to accept the patient's complaint as genuine. This not only adds to patients frustrations but it also delays treatment.
Fatigue has no specific tests to establish the cause of fatigue in sarcoidosis patients.
Although this virus has been implicated in chronic fatique syndrome, it has no role in causing sarcoidosis. Chronic fatigue syndrome is a poorly understood syndrome. Fatigue of sarcoidosis is self-limiting. If it persists then prednisone 10 to 20 mg. per day or chloroquine 250 mg. The progress of chronic fatigue in sarcoidosis is usually good.