The designations of mouse and human interferons as alpha or beta have been verified extensively in other laboratories. Acid- labile human alpha interferons have been prepared from time to time and are available on special order. Access Biomedical currently does not offer gamma interferons of any animal species. In Vivo Studies Cytimmune interferons have been examined repeatedly since 1977 for acceptability in pharmacodynamic and pharmacologic studies in mice, rats and rabbits with excellent results. In no case has toxicity been associated with these materials.
All buffers are suitable for parenteral use.
Buffer control samples are available, at no charge, to the unconvinced. Extensive experience has shown that Cytimmune interferon products are not toxic in vitro or in vivo. Consequently, we do not routinely test each lot for endotoxin or LPS activity. Orders for virtually any quantity are filled with material of a single lot so as to preclude uncertainty arising from the changing of lots during the course of study. In order to facilitate studies in vivo, we recognize that interferon costs cannot remain prohibitively high.