Additionally, LCMV can suppress the production of acetylcholine neuronal cells in cell culture. LCM may affect the autonomic nervous system, various sensory modalities, and cranial nerves. Meningitis occasionally may become chronic and may lead to hydrocephalus. Other organs, especially the testes, heart, and joints, may be involved. Orchitis usually is unilateral.
Cardiac involvement is typical of viral myocarditis.
The objective swelling, redness, and pain resolve within a few weeks. Variations in frequency occur locally and depend on rodent populations. Illness is more common during the fall and winter months. No racial differences exist in incidence of infection. No sexual predilection exists in incidence of infection.