Every attempt has been made to insure the accuracy of this material, however, medical science is constantly changing. If the information on this page differs from what you have been told by a nurse, pharmacist or physician, consult the person who told you differently or the manufacturer. Methylphenidate produces central nervous system and respiratory stimulation with weak sympathetic nervous system activity. A therapeutic response includes increased alertness and activity, decreased fatigue, and improvement in pain relief.
Elimination occurs through renal excretion.
If severe side effects occur, stop drug. Side effects should resolve within 24 hours. Anxiety and nervousness can be managed by decreasing the dose. Use of MAO inhibitors or vasopressors may result in hypertensive crisis. Metabolism of warfarin, anticonvulsants, and tricyclic antidepressants may be inhibited and effects increased.