When acute and generalized, patients are febrile, ill and demonstrate a leukocytosis. Withdrawal of systemic corticosteroid treatment may precipitate these flares. Often, an inpatient setting is appropriate. The importance of emollients in the treatment of psoriasis can sometimes be forgotten with the wealth of other therapeutic modalities from which to choose. Emollients hydrate and soften the scaly surface of psoriatic plaques.
Emollients also reduce the rate of transepidermal water loss.
They should be applied liberally at least BID, especially after bathing. Commonly used emollients include Eucerin, Lubriderm, Aquaphor, Purpose, etc. These may be applied QHS, with or without occlusion. The method of action is felt to be through inhibition of cell proliferation. Topical steroids are used commonly and are quite effective.