Urine samples provide analysis of robust chemicals, which are easily transported, are not temperature sensitive and above all are non-invasive. It is very accurate. This is a reflection of the function of the PST enzyme system. Sulphite is robust, will not deteriorate over a week in a plastic container, and can be measured by this non-invasive technique. A dip test is not suitable for this protocol.
Enzyme function is a variable activity, as is liver function.
Sulphite levels in the urine will reflect the degree of PST enzyme compromised. This is a liver stress measurement. It has correlated well with Vega testing of liver decompensation. Improvement of liver function and resolution into normality of this chemistry reading supports the clinical findings of improved attention, and concentration. The children seen in the Manchester practice vary in age from 2 to 34 years old.