Protocol summaries contain the study objectives, criteria for participation, as provided to NDRF by the investigating institution. The Center for Pediatric Hypotension Children's Hospital New York Medical College - Westchester Medical Center Valhalla, New York Autonomic Research at the Mount Sinai School of Medicine Efficacy of Midodrine in Patients with Neurally MediatedSyncope Midodrine HCI in Patients with Neurogenic Orthostatic Hypotension. A research protocol investigating the possibility of genetic links for orthostatic Intolerance Conditions is currently being undertaken at Vanderbilt University's Clinical Research Center. Venous blood samples are obtained for analysis and history detailed by questionnaire. Idiopathic Hypovolemia A family history of Orthostatic Intolerance within immediate family members.
All participants are adults.
Blood pressure and heart rate are measured lying down and standing at regular intervals. Blood samples are drawn for hormones affecting blood pressure control. Some studies require tilt table testing and medication administration. In rare cases, patients have developed skin reactions. Problems and side effects not known, and not expected at this time, could occur.