As a result the heart does not fill completely and EDV goes down. The drop in EDV reduces stroke volume producing a weak or thready pulse. The lower stroke volume drops cardiac output and blood pressure reducing baroreceptor stimulation and allowing heart rate to increase. Notice that ESV indicates that the heart does not empty completely with each beat. If the heart fails to empty completely, stroke volume falls as less blood enters blood vessels and cardiac output drops causing a drop in blood pressure.
Chronic hypertension is another example.
Systemic hypertension results in an increased pressure in systemic arteries into which the left ventricle must empty. As systemic pressures go up, the heart must contract more strongly in order to eject a stroke volume. Notice that increases in ESV result in corresponding decreases in stroke volume. Ventricular enlargements appear on an EKG as either right or left axis deviations depending upon the involved ventricle. By definition, peripheral resistance refers to the resistance to the flow of blood in the circulatory system.