Another class of drugs used are immunosuppressants. 6MP has also shown to help prevent fistulas. Both of these medications take several months before any effects are seen. They also can lower blood cell counts and monthly blood work is necessary. If a patients blood cell counts become too low, the medication must be stopped immediately.
Doctors can also use low doses of cancer fighting drugs such as methotrexate and cyclosporin.
The newest drug on the market is Remicade TM . The medication is given by IV infusion and can cause side effects ranging from headache and nausea to an anaphlactic response. Remicade TM was approved by the FDA in October, 1999. Any long term effects from the drug are not known at this time. Patients having fistulas have had their fistulas close.