Small populations and poor dispersal Small, isolated populations of running buffalo clover are prone to extinction from disruption, disease, and inbreeding. Competition from non-native plants Running buffalo clover does not compete well. The introduction of more aggressive exotic species, such as white clover, leads to increased competition for moisture, nutrients, space, and sunlight. Non-native clovers are believed to have introduced diseases and insect predators. A lack of prescribed fire has resulted in a loss of open woodlands and a reduction in running buffalo clover habitat.
Excessive grazing leads to direct mortality from predation or trampling or degrades the habitat.
Mowing may remove seed heads before seeds are mature but may help the clover by controlling competing vegetation. Running buffalo clover exists naturally on two sites in Missouri. As a result, private landowners can do little to manage lands in ways beneficial to running buffalo clover. However, landowners can be aware of the clover and how to identify it. If additional populations of running buffalo clover are located in Missouri, they should be protected and managed.