It may disappear but often leaves ascar. From a few weeks to a few months after the appearance of the chancre, an eruption usually appears on the body, consisting of a few red, pimply blemishesor a profuse crop of various types of blotches. At this stage, the germs are already widely distributed throughout the body. The infected person may havechills, fever, swollen lymph nodes, anemia, and pains in the bones and joints. The third stage of syphilis occurs generally from three to twenty years after the first lesion.
Hard tumor masses called gummas appear in different parts of the body.
In males the initial infection is usually on the penis whereas in females it is in the vagina or cervix. In a few cases, the infection may be in the oralregion. If the disease is left untreated, it leads to nerve disorder, cardiovascular disease and eventually death. Treatment Penicillin is highly effective in the treatment of the disease. The virus infects the helper T cell leading to impairment of the immune system.