It follows that all possible steps should be taken to reduce the need for allogenic blood transfusions. Frequent arterial sampling in ITU patients may cause significant blood loss and this factor remains poorly recognised. The aim of this study was to conduct a survey of intensive care units in England and Wales to assess what measures are currently being taken to minimise the amount of blood lost due to arterial sampling. In conclusion amifostine is well tolerated and can promote the growth of primitive hematopoietic progenitors and ameliorate the cytopenias in MDS patients. The Successful Use of Hemoglobin-Based Oxygen Carrier as a Primary Blood Substitute During Abdominal Aneurysm Repair with Large Blood Loss .
Human blood is the best available therapy for correcting the oxygern-carrying defect in anemia.
Partly because red blood cell transfusion is associated with several risks, hemoglobin solutions are under investigation as alternative therapy. In addition, this solution is derived from the abundant bovine blood supply, therefore, its availabil i ty is almost unlimited. The HBOC-201 solution is safe and effective in animals with significant hemorrhage as well as in patients undergoing aortic surgery . We report the use of a HBOC-201 solution as a blood substitute in one patient who underwent abdominal infrarenal aneurysm repair. Although in the present case the surgery was associated with unusually large blood loss, the patient received no banked blood.