GladePyC aims to fill this little gap.
Individual widgets are accessible by their name as attributes of instanciated objects.
There is support for connecting a whole set of signals at once, based on the name of callbacks, which presence is checked as methods of the controller. Each value is accessed as an attribute of the instanciated object, through an attribute with the same name as the corresponding widget. I will write documentation when things have matured. Gladepyc can now be considered ready for production. Don't know what's the difference after all, and it seems mixed up in Glade too.