Apply approved fungicides to the crop at regular intervals. You can get current spray recommendations from your Cooperative Extension office. Bacterial Wilt Bacterial wilt is a common, often destructive, disease of cantaloupe and cucumber. This disease can cause nearly complete losses of a planting before the first harvest. Squash and pumpkin are also susceptible, but damage to them is usually less severe.
Individual leaves become dull green and wilt soon after infection.
These first symptoms are often associated with insect feeding damage. As the disease progresses, more leaves wilt and eventually the entire vine is affected. Finally, the leaves and vines shrivel and die. Even the fruit on affected vines shrivels. With a sharp knife, cut through a wilted vine near the crown.