Chronic toxicity is more common, with signs manifesting within several weeks of ergot consumption, and field exposure to ergot is more common than processed feed or flour exposure. The clinical signs can vary, but often begins with swelling of and pain in the extremities, especially the hind legs, due to the constriction of blood vessels. Later, sensation is lost in the affected areas, and dry gangrene can develop. In addition to the vascular effects, neurologic signs are often seen, such as apprehension, nervousness, and convulsions. Some animals may show signs of depression.
Death can occur, but only with significant quantities ingested.
In sublethal cases, once the source of ergot is removed, recovery from neurologic signs is likely, but recovery from the vascular effects and gangrene is not likely. Ergot poisoning has been implicated in cases of abortion in large animals. Remove animals from the source of ergot, whether in feed or pasture. Call a veterinarian if nervous signs are present. In cases of dry gangrene, the affected portion will be likely to spontaneously amputate.