Usually, these patients have a history of previous involvement of other organs. These lesions frequently work as a tumoral lesion but it can also be a meningeal type. Cerebrospinal fluid alterations are not characteristic. Cutaneous lesions are important because of its frequency as well as its diagnosis value. It occurs predominantly in the juvenile form.
Facial lesions are more common.
As the general characteristics of PBmyc, also the cutaneous lesions are polymorphic, various characteristics may be seen in the cutaneous lesions, although ulcerated lesions are, by far, the commonest of all. Other organs involved may be the eyes, adrenal glands, thyroid, urogenital tract, heart, spleen. striated muscles. Biopsy may be diagnostic. Culture should be performed, since it may prove the activity of the process. Serologic tests are useful for the diagnosis of P. brasiliensis .