GBS does not affect level of consciousness, cognitive function or pupillary signs. Diagnosis is based on clinical picture. Insidious onset, unilateral, unknown etiology. Clinical Presentation- Symptoms develop slowly, so years may pass before a diagnosis is established. A chronic, degenerative disease that affects the myelin sheath and conduction pathways of the central nervous system.
Illness is characterized by periods of remission and exacerbation.
Etiology is unknown, thought to be either due to a viral infection or an autoimmune response. The course of MS is unpredictable. A few categories of progression have been identified. Etiology possibly autoimmune. Myasthenic Crisis Myasthenic crisis- sudden exacerbation of myasthenic symptoms, usual precipitating event is infection, although in some cases there is no evident precipitator.