This suggests it would be fatal to humans only if ingested in very large amounts. This indicates that chloramben has about the same toxicity when applied to the skin as when ingested. Studies indicate that chloramben is not a mutagen. This chemical's carcinogenic status has not been determined. Chloramben exposure can be irritating to mammals, but it is not known to be toxic to any organs.
Animals rapidly excrete chloramben.
When pregnant rabbits were given high doses of chloramben during the sensitive period of gestation, no developmental defects were seen in the fetuses. Pregnant rats fed lower doses of chloramben during the sensitive period of gestation were not affected, but fetal deaths increased and fetal skeletal development was not complete. At even lower doses, no increase in fetal deaths were seen, but the bones were not fully developed. Most bacterial and mammalian cell assays of chloramben indicate that it is not toxic to genetic material. Rats given high daily doses of chloramben for 80 weeks did not show carcinogenicity.