Diseases that cause constipation include neurological disorders, metabolic and endocrine disorders, and systemic conditions that affect organ systems. These disorders can slow the movement of stool through the colon, rectum, or anus. Neurological disorders that may cause constipation include multiple sclerosis, Parkinson's disease, chronic idiopathic intestinal pseudo-obstruction, stroke, and spinal cord injuries Metabolic and endocrine conditions include diabetes, underactive or overactive thyroid gland, and uremia. Systemic disorders include amyloidosis, lupus, and scleroderma. Problems with the colon and rectum.
Colonic inertia is caused by decreased muscle activity in the colon.
Pelvic floor disorders including rectocoeles, pelvic descent, and nonrelaxing puborectalis syndrome may all cause constipation. Constipation associated with rectal bleeding or symptoms of anemia are serious symptoms that should be reported to your physician. I n young people with mild symptoms of constipation, a medical history and physical examination may be all the physician needs to suggest successful treatment. The tests the physician performs depends on the duration and severity of the constipation, the person's age, whether or not there is blood in stools, recent changes in bowel movements, or weight loss. Recording eating habits, medication, and level of physical activity or exercise also helps the physician determine the cause of constipation.