Retinoids - Decrease cohesiveness of abnormal hyperproliferative keratinocytes and may reduce potential for malignant degeneration. Modulate keratinocyte differentiation. Have been shown to reduce risk of skin cancer formation in renal transplant patients. Makes keratinocytes in sebaceous follicles less adherent and easier to remove. Recommended for relief of minor skin irritations and pruritus associated with common dermatoses and dry skin conditions.
Lactic acid is an alpha-hydroxy acid with keratolytic properties.
Contraindications Documented hypersensitivity Interactions None reported Pregnancy C - Safety for use during pregnancy has not been established. Cause cornified epithelium to swell, soften, macerate, and then desquamate. By dissolving the intercellular cement substance salicylic acid produces desquamation of the horny layer of skin, while not affecting structure of viable epidermis. Hydrate skin and enhance effects of medication by soaking affected area in warm water for 5 min prior to use. Remove any loose tissue with brush, washcloth, or emery board and dry thoroughly.