The tool can be held near its center of gravity to reduce the amount of force needed. The weight is as light as possible. Don't use a heavier tool than is necessary. You can use a power or oblique grasp. Avoid tools that require pinch grips.
Handles are well padded and long enough to distribute force over entire palm.
It has built in vibration dampening features. It is easy to open and close without effort. Buy tools that are spring-loaded. To summarize, there are 3 major methods to control awkward postures. Change Orientation of Work Place frequently used items within easy reach.