I would be cautious. The benefits have to be balanced against the potential side effects. Both methotrexate and glucocorticoids have clear toxicities, especially in children. If the progress of localized scleroderma in children could first be halted by a treatment such as the one reported in Arthritis Today , it might then be possible to permanently reverse any disfiguring effects using the microsurgery techniques described and illustrated in the Scleroderma Foundation's Newsline article. The Scleroderma Foundation in no way endorses any drugs or treatments reported on this website.
Information is provided as a resource to be used with discretion.
Because the manifestations and severity of scleroderma vary among individuals, personalized medical management is essential. Therefore, it is strongly recommended that all drugs and treatments be discussed with one's physician to assure proper evaluation and treatment.