First, it is colder, with a summer night temperature of -25 C common at 7000m. Face masks, one piece down suits, windsuits, Gortex covering for sleeping bags and clothing have revolutionised the high altitude wardrobe. Advice from well established manufacturers should be sought early in planning, as much of the gear has to be specially made and fitted. Plastic double boots, being extremely light, are the norm. Plastic boot disease i.e. white, discoloured, swollen feet is difficult to deal with - the only solution is to allow the feet to dry out.
Frostbite is usually a product of several factors and it is frequently avoidable.
Since one's appreciation of the degree of cold is very poor, in temperatures below -15 C it is worthwhile carrying a miniature, plastic encased thermometer, which weighs only a few grams. The treatment of established serious frostbite is dealt with elsewhere - but descent is essential. The occurrence of frostbite almost always means the end of any serious climbing for the patient on the current expedition and much extra work for colleagues. Drugs are of little use. Butane-propane mix stoves are quick and easy to use.