To view a faculty members area of research interest, click on department affiliation. Department Pages Use of cellular and molecular approaches to analyze the role of proinflammatory cytokines in pregnancy with a focus on the interleukin genes using mouse models. Department Pages Role of macrophages in the uterus and placenta with a focus on learning how the special conditions of pregnancy influence their functions. In my laboratory, cellular, biochemical and molecular approaches are incorporated to investigate the role of the TIMPs in uterine development and function.
Endometriosis is one such disease in which TIMP expression is reduced.
Cellular and molecular approaches are applied to both In vitro and In vivo developmental models designed to understand initiation of pregnancy, fetal growth retardation, and gestational trophoblast disease. As related to these hormones, our studies involve analysis of the mechanisms regulating cell differentiation, transcription factor regulation of basal gene expression, and identification of related signal transduction pathways.