Every biological process is regulated by several different control mechanisms.
Our research focuses on how the individual mechanisms work and how they are coordinated with each other. We are studying the regulation of the glyoxylate bypass in the bacterium Escherichia coli . We chose this organisms because it can be manipulated with a variety of powerful genetic techniques. Specific research projects make extensive use of molecular biology, genetics, protein chemistry, and enzymology. In Escherichia coli , expression of the enzymes of the glyoxylate bypass is controlled by a complex network of transcription factors.