Exogenous endophthalmitis usually is associated with trauma or intraocular surgery. In endogenous endophthalmitis, urinary track infection was the most common primary site of infection and nearly all patients are diabetic. Early recognition and appropriate treatment is crucial, since E coli endophthalmitis has an extremely poor prognosis. Depending on the severity, most patients need aggressive management and early medical and surgical intervention. Of these infections, E coli is rare a cause.
Incidence is higher in association with intraocular foreign body.
Of these infections, E coli is a rare cause. Corneal infection due to E coli produce indolent corneal ulcers with poor prognosis because most of these patients of have an underlying immunocompromised disorder or have abnormal corneal surface with compromised protective barrier. Men are 4 times more likely to have ocular trauma than women, which may lead to bacterial endophthalmitis. For corneal ulcer due to E coli , no difference exists in frequency between the sexes. Also, endophthalmitis may occur in neonates following meningitis.