It depends on what MTA features said program might include, and what the situation requires. I used send mail as my mta. Sendmail is not well-suited for the home user with a dynamic IP dialup account. You can make it work, but it will be painful. I notice the normally vocal crowd of people advocating other MTAs is silent on this issue.
Evolution is still a work in progress.
I cannot get sendmail to run. All mail is delivered through that central host. A bare minimum of local processing is done. No local delivery is possible. The local machine's identity is obliterated.