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Fibrosis is a process that follows chronic inflammation.
Fibrotic tissue is like a scar tissue, thick, and rigid, due to excess accumulation of protein below the skin. Diagnosis Hallmark of Scleroderma, the skin fibrosis is responsible for its name. The diagnosis is clinical, and requires no laboratory or special testing. Occasionally, your doctor may consider it necessary to perform a skin biopsy. This is usually the case where infrequent patterns or areas of skin become tight and firm.