Histology following CT guided FNAC Thymoma Discussion Thymomas affect men and women with equal frequency, generally afflicting adults above 40 years of age. Sudden cardiac death due to right artrial compression may occur. Thymomas may be associated with myasthenia gravis, and other systemic disorders including pure red-cell aplasia, hypogammaglobinaemia, endocrine, and connective tissue disorders. Imaging Findings Radiographs of chest reveal a contour abnormality of the anterior mediastinum, as the mass displaces both visceral and parietal pleura, resulting in smoothly marginated lobulated borders against the lung. They may extend to both sides of the mediastinum or may arise in the cardiophrenic angle.
Calcification is common, is usually linear, thin and peripheral.
CT Replacement of the anterior mediastinal fat by denser soft tissue is the primary sign. Mediastinal involvement by thymomas is usually intrathoracic and mostly pleural. MRI Multiplanar imaging is useful for thymoma evaluation. Staging Masaoka Classification includes 5 stages, staging is usually performed at the time of surgical intervention. 2-4b are invasive Therapy Surgical resection is the preferred treatment for patients.