The chance of developing a clot-related problem can be reduced by using the lowest dose of estrogen that still proves effective. If a problem surfaces anyway, you'll have to stop using the patch. Likewise, you should discontinue the patch and call your doctor immediately if you suffer a loss of vision, any other eye problems, or a migraine headache. Hormone therapy occasionally causes a rise in blood pressure. If you have a blood pressure problem, use CombiPatch with caution and have your pressure checked regularly.
Hormones also tend to cause fluid retention.
If you have a condition that could be aggravated by excess fluid such as asthma, epilepsy, migraine headaches, heart disease, or kidney problems use CombiPatch with caution. Because estrogen can increase triglyceride levels, you'll need to be closely monitored if your triglycerides tend to be high. If you have diabetes, CombiPatch may also affect your blood sugar levels. Estrogen therapy occasionally causes abnormal uterine bleeding or breast pain. In view of concerns about cancer, you should have these symptoms checked by your doctor.