I have been experiencing pain behind my eye and have noticed that depth perception has been affected with slight blurring. It has been recommended to have a spinal tap, but at this time I do not feel it has come to that point. Negative brain MRI but positive spine does happen sometimes even with normal lower SEPs. MRI often does not show an optic nerve lesion but visual evoked potentials should be abnormal. The spinal cord ends at L1.
Lesions can be anywhere from cervical to there.
MS is not a radiological diagnosis. The history and neurological examination are an integral part of the diagnosis. In the last two years it has become more progressive and my doctor now says I am secondary progressive. There may be some value in comparing a new MRI to a previous MRI to see if there are many new plaques or any active plaques. Also I have three cousins with MS, two still living, around same age, same symptoms.