Typically, lesions develop slowly into chronic, well-demarcated plaques on the skin, which may persist for many years. Typical locations include the knees, elbows, scalp, and intergluteal cleft. Mucous membranes may also be involved, with migratory stomatitis and glossitis. Certain medications, including beta-blockers and lithium, can exacerbate this type of psoriasis. The importance of emollients in the treatment of psoriasis can sometimes be forgotten with the wealth of other therapeutic modalities from which to choose.
Emollients hydrate and soften the scaly surface of psoriatic plaques.
Emollients also reduce the rate of transepidermal water loss. They should be applied liberally at least BID, especially after bathing. Commonly used emollients include Eucerin, Lubriderm, Aquaphor, Purpose, etc. These may be applied QHS, with or without occlusion. The method of action is felt to be through inhibition of cell proliferation.