Antidepressants can be very effective. They are generally non-addictive and do not lose effectiveness with prolonged use. Three people out of four respond to antidepressants. Of those that don't, about half will respond to a different medicine. Most people with depression will respond to treatment after two weeks but in some people, it can take up to four weeks.
All drugs work at the same speed.
Studies have shown that continuing antidepressants for at least six months after a first episode reduces the risk of further episodes. Long term treatment of up to five years may be necessary for some people. Drug choice Because all antidepressants are equally effective, doctors choose medication according to side-effects and how well they mix with other medicines taken. It may take one or two attempts before a suitable medication is found. Stopping Antidepressant drugs When taken for six weeks or longer, antidepressants should not be stopped suddenly as they have the potential to cause withdrawal symptoms.