While most patients survive to early childhood, respiratory problems can further shorten life. Weakness in leg, hip, shoulder, arm and respiratory muscles. Calf muscles are often enlarged. Disease progresses slowly. Wheelchair is often required by age 30.
Life span is unaffected.
Weakness in the tongue, hands or feet which slowly spreads to other parts of the body. A relatively mild form of spinal muscular atrophy, it has little impact on life expectancy. Weakness of limb muscles, especially legs, and of muscles involved in talking, chewing and swallowing. Occurs in men. Slowly progressive over decades.