Polyarteritis nodosa is a vasculitis of small and medium-sized blood vessels. Juvenile scleroderma is rare in children but includes both localized and systemic disease. Localized scleroderma includes several types of skin lesions Systemic scleroderma is similar to that experienced by adults and includes Raynaud's phenomenon and skin, musculoskeletal, gastrointestinal, pulmonary, cardiac or renal involvement. Raynaud's phenomenon is often a symptom of connective tissue diseases, especially scleroderma. Sjogren's syndrome is often called Sicca syndrome if it is a symptom of connective tissue diseases.
Diagnosis is made by skin biopsy with evidence of inflammatory cells in the subcutaneous tissue.
Hypermobility syndrome represents extreme variation of the usual range of joint motion. Girls are more often affected than boys, and frequently there is a family history of hypermobility. Non-inflammatory disorders are important causes of chronic or recurrent pain in children. These include growing pains, primary fibromyalgia syndrome, reflx sympathetic dystrophy and overuse syndromes. The information provided by this website should not take the place of advice and guidance from your health-care providers.