Abdominal pain, fever and blood in the urine may occur, but are not common. There may be nausea, vomiting, diarrhea, weight loss, high blood pressure, constipation or fatigue. The tumor may grow to a very large size without many symptoms. Children may look healthy and play normally up until the day the mass is discovered. Wilms' tumor can often be treated successfully depending on the stage of the tumor at detection and the age and general health of the child.
Early detection is the key.
The chemotherapy regimen currently preferred to treat Wilms' tumor consists of the drugs dactinomycin and vincristine, which may be combined with doxorubicin.