Never did he challenge G-d. Here are a few of my suggestions. Maybe you have your own. Everyone wants a successful career, good health, long life. In the real world no one you talk to has it all.
Every family has some sorrow, some failure.
Loss of health, disappointment. It's part of the shared and common human lot. It's funny, you know the ultimate form of democracy is suffering, because nobody is exempt. Not money, not prestige, not connections, nothing can spare you at some point and somewhere from suffering and sorrow. From disappointment and frustration.