Cocaine is one of the most abused drugs in the United States.
Its addiction and overdose are still untreatable. When giving a cocaine addict a single dose of this vaccine, it will destroy cocaine molecules in the blood circulation before the drug can even get to the brain. These are IgGs with 4 clones that contain lambda light chain and the other 5 clones contain kappa light chain. The carboxyl terminus of V H , and the amino terminus of V L were covalently joined by a flexible polypeptide linker, which consisting of stretches of Glycine and Serine residues. Panning selections were performed against cocaine transition-state analogies on this recombinant phage.