Depression is one of the most frequent mental disorders in the elderly.
However, it remains underdiagnosed and undertreated, largely because patients and their family members, relatives or caregivers believe that depression is simply part of the normal aging process. Moreover, the symptoms and duration of depression in the elderly are often different than those in younger people, and more difficult to identify. 5 Activity in the norepinephrine, dopamine and serotonin systems is reduced in patients with Alzheimer's disease, which leads to a diminished threshold for functions that are controlled by these neurotransmitters. As a result, antidepressants have been historically prescribed in an attempt to re-establish a healthy neurochemistry. In addition to treating depression, an SSRI may also help to resolve emotional disturbances such as confusion or restlessness.