This is believed to loosen comedones and facilitate extraction. Makes keratinocytes in sebaceous follicles less adherent and easier to remove. Cause cornified epithelium to swell, soften, macerate, and then desquamate. Contraindications Documented hypersensitivity Interactions None reported Pregnancy C - Safety for use during pregnancy has not been established. Treat these lesions with appropriate antibiotics.
Infections often are recurrent.
Spontaneous resolution has not been described. All lesions persist unless treated. They will often grow at puberty. Report of three cases localized on glans penis. Naevus comedonicus in homozygous twins.