FHC is a clinically and genetically heterogeneous autosomal dominant inherited heart disorder that causes a high incidence of sudden heart failure.
Chest pains differ from individual to individual.
They may be sharp or aching, have prolonged duration and may worsen after treatment with medication. Familial Hypertrophic Cardiomyopathy is caused by a mutation in the gene encoding a part of the multi-subunit muscle protein myosin, called a myosin heavy chain. A myosin molecule is shaped like a rod with a bulge at one end, called the head. The other major muscle protein actin binds to the head. After actin binds to the head, ATP splits to provide the energy necessary for muscle contraction.