Tiny, aphthoid ulcerations of the mucosa with underlying nodules of lymphoid tissue are the earliest signs of pathology. Sometimes these regress, while other times they progress to involve all layers the intestinal wall. The development of transmural inflammation with edema, deep ulceration and fibrosis is responsible for obstruction and mesenteric abscesses. Cancer and perforation are rare complications. No specific treatment is known, but the management of each case must correlate with the individual symptoms and treated symptomatically.
Good nutrition is essential.
Restores integrity to the mucosal lining. Comfrey-pepsin for mucosal healing.