This is one of the tricylic antidepressants. Imipramine helps with anxiety and depression and is used when stimulant medication fails to get a response or it not appropriate to be given. It is not as effective with the core ADHD symptoms. Only the first two are usually seen however this medication should be carefully monitored by the doctor and regular blood pressure and pulse checks should be made. Also if there is a concern EEG recordings can be taken.
Imipramine inhibits re-uptake of norepinephrine.
There is a very slight concern of heart deaths and Clonidine must be withdrawn gradually. Overdose is very dangerous. Clonidine blocks norepinephrine auto-receptors. The patch may be cut to adjust doseage. It can take up to 2 - 4 weeks to see any effect and maximum effect can take several months.