Explain discontinuous variation and its relevance to Mendel's experiments. Answer ANY TWO of the following. Explain any calculations, symbols or assumptions. A woman with the recessive genetic disease anhedonia and a man of normal phenotype have several children. How would your answer to A differ if anhedonia is carried by an autosome.
Gene therapy is a problematic area, both technically and ethically.
A. Explain how gene therapy of somatic cells could be accomplished. C. Explain how gene therapy of germ cells could be accomplished. Genetic screening techniques are technically well-established, but can involve ethical problems. A. Explain the techniques used to determine whether an adult is a carrier of a recessive genetic disease or has a dominant disease that has not yet been expressed. B. Describe two different techniques used to obtain fetal cells for such testing.