In general junk mail is best ignored, i.e., delete it immediately and do not respond. You should not reply directly to junk mail, unless it has come from someone you know and you believe you can educate them. Most junk mailers know exactly what they are doing, and that it is anti-social and against the rules of many systems, and will not take any notice of complaints. Some junk mailers retaliate strongly against complainants, adding them to further mailing lists, complaining to their employers etc. Much junk mail has forged headers.
Junk mail begets junk replies.
When junk mail is sent to a mailing list some people reply to everyone else on the list as well. Doing so irritates everyone else on the list, and continues to give the junk mailer the added publicity they desire. It adds further to the traffic congestion caused by the original mail. Allowing yourself to get angry is playing the game that those causing the nuisance want you to play. You will be positively contributing to a solution by showing restraint.