This is a silent killer if ever there was one. This problem is rare today, but don't discount something your spouse may be bringing home. Many people are sensitive to allergens given off by cockroaches. This is a particular problem in the south, where cockroaches are more prevalent. But choose your exterminator carefully.
Many asthmatics also react to insecticide.
If you have asthma and are concerned that something in the house may be triggering attacks, consult an allergist. But a word of caution. Some doctors practice allergy without special training in the field. It is difficult to sometimes interpret the skin tests many allergists use, and specialized knowledge can be helpful. If you consult an allergist I recommend you choose one who is board certified in the field.