Ian Roberts , Director, Child Health Monitoring Unit . Binding and transport, osmotic pressure, free radical scavenging, platelet function inhibition and antithrombotic effects. Consequences of decreased plasma albumin 1. Decreased ligand binding. In critical illness, there is a stronger correlation between colloid oncotic pressure and Total protein than with albumin.
Albumin decreases in burns, liver disease, renal disease, pre-eclampsia, stress and sepsis.
Albumin as a prognostic index Serum albumin concentration in critical illness is inversely related to the risk of death.