Harvard Medical School had a hyperbaric chamber built in 1928. It provided a university based medical research program. In the last four decades great strides in HBO2 research has raised the value of this unique therapy. University studies have expanded the list of conditions usefully treated with compressed oxygen. Related to crush injuries it is apparent that most pain is a result of swelling around sensitive nerves.
Hyperbaric oxygenation acts internally to reduce swelling and can reduce pain.
She was driven to a hyperbaric chamber 12 hours after her injury. She completed 15 hyperbaric sessions so that in 4 weeks she completely healed with no scar formation. When ischemia is severe and persistent it may lead to an anaerobic form of tissue metabolism that may perpetuate the entire ischemic process. W. Boyd A Textbook of Pathology 8th edition pg. Irritation of nerve roots with attending muscle spasm along the segmental distribution of the nerve root can create ischemic changes that, if not corrected, can lead to permanent impairment.