If the diagnosis is made de novo in the ED, only rarely is emergent consultation necessary. Exceptions include sudden airway compromise or acute SVC thrombosis, which may occur from an indwelling catheter. However, SVCS rarely presents as an acute life-threatening emergency. As such, considering the diagnosis may be more important than the actual definitive care when making therapeutic decisions. Glucocorticoids - These agents decrease the inflammatory response to tumor invasion and edema surrounding the tumor mass.
Glucocorticoids have anti-inflammatory properties and cause profound and varied metabolic effects.
In addition, these agents modify the body's immune response to diverse stimuli. Decreases inflammation by suppressing migration of polymorphonuclear leukocytes and reversing increased capillary permeability. Dose must be individualized. Fortunately, this is rare. Potential causes include indwelling catheters.