It should not be used for longer than one month at a time. It is not advised to take ephedra for more than three months without a break. This can cause adrenal exhaustion and a loss of efficacy of the drug -Do not use ephedra products that contain caffeine, including those with guarana and cola nuts. Choose an ephedra product that uses the whole ephedra herb, not just ephedrine. Reduce dosage if side effects occur, including headaches, nausea, insomnia, anxiety, or urinary problems.
Ephedra works best when taken on an empty stomach.
For optimal results, take one hour before meals. To prevent insomnia, refrain from taking too late in the day. The maximum safe dosage is 100mg per day. This depends also on body size. Do not take ephedra if you are currently taking a MAO inhibitor and check with your doctor if you are currently taking other prescription drugs.