Heavily keratinized warts may not respond as well as those on moist mucosal surfaces. Few data on the efficacy of TCA are available. One study among women showed efficacy and frequency of patient discomfort to be similar to podophyllin. No data on the efficacy of bichloroacetic acid are available. Few data on the efficacy of electrodesiccation are available.
Local anesthesia is required, and patient discomfort is usually moderate.
Management should be carried out in consultation with an expert. Vaginal Warts Cryotherapy with liquid nitrogen. The use of a cryoprobe in the vagina is not recommended because of the risk for vaginal perforation and fistula formation. Repeat weekly as necessary. If warts persist after six applications, other therapeutic methods should be considered.