ApoE added to chylomicron. TG's are converted to FA's and glycerol and transported into tissues. Beta-oxidation within muscle. FA's activated, transported to mitochondria via carnitine shuttle, oxidized in two carbon units, generating one acetyl coA, one FADH2, one NADH per cycle. This will be metabolized to succinyl coA via a set of reactions that require biotin and vitamin B12.
Eukaryotes have unique membrane bound organelles that can carry out specialized sets of reactions.
Peroxisomes are generally used to metabolized very long chained fatty acids and does so with distinct enzyme isoforms, but a very similar sequence. The first reaction is the most different. People with this disorder cannot metabolize FA's with a length of 6-12 carbons. A fatty acid is then built from this intermediate, two carbons at a time. Other fatty acids are generated via other reactions from palmitate.