Has little effect on venous capacitance vessels.
Diastolic response is often greater than systolic.
Hypotensive effect may be limited by sympathetic reflexes which increase heart rate and stroke volume. Coronary artery disease Dissecting aneurysm Hypersensitivity Adverse Reactions Reflex tachycardia Hypotension Facial flushing Headache Diaphoresis Anxiety Nausea and vomiting Drug Interactions Concurrent use of diazoxide may result in severe hypotension. Color changes may occur when given with glucose solutions.