Smoking, low lung function, underweight and dyspnea were confirmed as COPD mortality risk factors. A positive skin test for common aeroallergens did not increase the risk of COPD mortality. Lung Cancer Data have shown that gastrin-releasing peptide plays an important role in neoplasia by stimulating cell proliferation. In the study, expression of the GRPR gene in bronchial and lung cells and tissues was determined from 38 women and 40 men with and without lung cancer. It was hypothesized that since the GRPR gene is expressed more frequently in women than in men in the absence of smoking and that since expression of this gene is activated earlier in women in response to tobacco exposure, the presence of two expressed copies of the GRPR gene in females may be a factor in the increased susceptibility of women to tobacco-induced lung cancer.
Full publications are in preparation.
In 1997, CVD claimed 953,110 lives which is more than the next seven leading causes of death combined. In comparison, cancer, the second leading cause of death in the US, killed 539,577 people in 1997. The major risk factors for CVD include smoking and obesity. What is not well publicized is that women have heart attacks 10 years later than men, and that women have a significantly greater chance of dying during that first heart attack than men. According to a report from the Early Postmenopausal Intervention Cohort Study Group, alendronate can be used as an alternative to estrogen-progestin for prevention of postmenopausal osteoporosis.