Hot flashes are the most frequently reported side effect of tamoxifen treatment.
Although hormones are an effective treatment, their safety is questionable in women with breast cancer. It is therefore important to evaluate nonhormonal treatments for hot flashes. Patients in the placebo and treatment groups were similar in age, duration of tamoxifen use, reported frequency and duration of hot flashes at baseline, and dropout rates. Ann Intern Med. R.F. Raubertas, V. Dragalin, G.R. Morrow.