It resembles gentian and quassia in its properties. The Coptis family is closely linked to that of the Hellebores. Its bitterness is imparted to both water and alcohol, but more readily to the latter. As there is neither tannic nor gallic acid, the activity is due to berberia or berberine, which is associated with another alkaloid called Coptine or Coptina, resembling hydrastia. It also contains albumen, fixed oil, colouring matter, lignin, extractive, and sugar.
Authorities differ as to the presence of resin.
It may be used as other pure bitters. In New England it is valued as a local application in thrush, for children. It is stated to be good for dyspepsia, and combined with other drugs is regarded as helpful in combating the drink habit. It grows in the Mishmi Mountains, East Assam, is imported into Bengal in little rattan bags, and is thus sold in the Indian bazaars. Large quantities have been sold in London.