This is a very short-lived solution because any benefits of alcohol soon wear off and the drinking becomes part of a routine and therefore difficult to change. In consequence, the drinker finds that he or she can take large quantities but feel very little benefit. This tolerance or habituation is a step toward dependence. The down side of the emotional release associated with drunkenness is that it often leaves us tired, depressed and hung over as the blood alcohol level falls. There is evidence that changes in the chemistry of the brain itself may be produced by alcohol and that these changes increase the likelihood of a depressed mood.
Hangovers are in themselves depressing experiences.
The drinker wakes feeling ill, anxious and jittery. The day may be spent ruminating over the guilt associated with the events of the previous evening. As drinking bouts become habitual, there may well be troubles at home, conflicts with partners and family, quality of work deteriorates and the drinker will often feel that he or she is being unjustly criticised by colleagues. Failing memory, sexual impotence and declining physical health add to the sense of despair. Given these circumstances, it is hardly surprising that depression and even thoughts of suicide are common events in the life of someone who has become seriously dependent on alcohol.