In patients with bleeding oesophageal varices 20 units over 15 mins initially to control bleeding. It is contraindicated in hypersensitivity and vascular disease. Precautions Precaution should be taken in patients with migraine,epilepsy, asthma, heart failure, pregnancy, lactation and in renal failure. Interactions Clofibrate, Carbamazepine, chlorpropamide, urea, tricyclic antidepressant can potentiate the activity of vasopressin. Demeclocycline, lithium, noradrenaline, heparin, and alcohol decrease vasopressin's effect.
Ganglion blockers can increase the sensitivity to pressor effect.
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