Improvements in feed efficiency due to ionophore use increase as the level of roughage in the diet increases. In higher concentrate diets, there are other subtle benefits from ionophore use. Primarily, feed intake of high grain diets is less variable when ionophores are used. This in turn can lead to a reduction in the potential for acidosis and bloat. Use of ionophores in higher than approved levels can be toxic to cattle.
Horses are especially susceptible to ionophore toxicity.
Horses should not be allowed to eat feed or supplements containing ionophores . Coccidiostats Coccidia are protozoal organisms that can invade and destroy the intestinal mucosa of cattle. They are generally present in most animals at subclinical numbers and do not affect the performance and health of cattle. At certain times, however, their numbers increase to the point that production efficiency is decreased and irritation of the digestive tract becomes so severe that bloody feces and scouring can result. Interpretation of fecal coccidia is difficult, since a clinical problem can be present even with low coccidia counts.