Detailed evaluation of the cause of growth delay has rarely been performed. The possibility of growth hormone deficiency is now being looked into. It has not been found to date. The chest often has widely spaced nipples. Shoulders are commonly rounded or slouched.
Finger tips are blunt and squared.
A third of patients have dental malocclusion with an increased potential for cavities. It is important to evaluate the child or adult with Noonan Syndrome for clotting problems, especially prior to surgery, as in general they are easily treated. The majority of females have normal puberty and are fertile. These respond well to speech therapy. The frequency of Noonan Syndrome may be as high as 1 per 1000 live births.