Symptoms occur late and include fatigue, abdominal distention, anorexia, early satiety, nausea, constipation, urinary frequency, and shortness of breath caused by pleural effusion or Estrogen production by certain stromal tumors may cause abnormal uterine The most frequently noted physical symptoms are pelvic pain and ascites associated with a pelvic mass. An adnexal mass that is bilateral, irregular, solid, or fixed is suggestive of malignancy. Rarely, a testosterone-secreting tumor will produce Ovarian Cancer physical findings of virilization. In patients over 45 years of age, colonoscopy or a barium enema and proctoscopy is done to rule out the presence of colonic involvement or Ovarian Cancer, ovaries, cancer colon cancer. Chest x-ray should be obtained to detect pleural Ovarian Cancer, ovaries, cancer effusion or metastatic disease.
Cervical cytology is completed to rule out cervical cancer.
Endocervical and endometrial sampling is necessary if there is abnormal uterine bleeding. Mammography is appropriate to exclude primary breast Ovarian Cancer, ovaries, cancer cancer, which may metastasize to the ovaries. Ultrasound, CT, or MRI may be useful for preoperative Ovarian Cancer evaluation or for assessment of disease status. Tumor Markers Blood plasma should be assayed for levels of circulating tumor markers in patients suspected or known to have ovarian cancer.