Frederickson has developed an MVP syndrome support group based upon clinical experience that convinces her that MVP is only one component of a larger disorder. MVP is seen in all ages, races and socioeconomic groups. Symptoms are not usually due to poor cardiac function but rather an imbalance in the nervous system that gives a wide range of symptoms. Patients are frequently accused of being depressed or merely anxious as a source of their symptoms but many studies have shown that MVP patients have no greater incidence of psychiatric problems than the general population. In addition, the additional somatic disorders are reported in a condition typically described as asymptomatic.
Antibiotic dosages vary according to the patients ability to tolerate a particular regimen.
The American Heart Association recommends 3.0 grams of amoxicillin orally one hour before the procedure and then 1.5 grams six hours after the initial dose. Depending upon the severity of the MVP, the treatment may be more powerful than an occasional dosing of antibiotics. For severe MVP, replacement of the valve may be in order. Mechanical valves have the advantage of durability but the disadvantage of causing blood clots. Biological tissue valves negate the need for anti-coagulant medication but are less durable and more likely to be rejected by the immune system.