Through the artificial sense sequences that led to normal implantation, Bagchi verified that the blockade in implantation was not an artifact of the novel technology, which might have simply thrown a molecular monkey wrench into the works. In fact, her research represents a technical milestone, pioneering in vivo use of an antisense technique that scientists had previously used only in cultured cells. Bagchi's lab is one of five groups nationwide collaborating to understand uterine receptivity. The consortium was created and is supported by the U.S. National Institutes of Health. We meet every six months to discuss our research.
Implantation is one of today's major challenges in the study of human reproduction.