Available over the counter or by prescription, they fight inflammation or swelling and relieve pain. Topical pain-relieving creams, rubs, and sprays can be applied directly to the skin. There are many brands available over the counter. Narcotic pain relievers may be needed in cases of severe pain. Corticosteroids are typically injected into affected joints rather than taken orally to relieve the pain.
Hyaluronic acid is a newer medication for joint injection, used to treat osteoarthritis of the knee.
This substance is a normal component of the joint, involved in joint lubrication and nutrition. Glucosamine and chondroitin sulfate are found in the synovial fluid of the knee. Several studies have reported some pain relief and improved function from taking either one or a combination of the two natural substances. It is available over the counter. For some people, surgery helps relieve the pain and disability of osteoarthritis.