Workers are generally exposed to many diverse chemicals that may cause both subtle and overt cellular damage, which becomes part of a pathogenic process. This laboratory studies the cellular toxicity of industrial chemicals to develop sensitive methods for detecting cellular effects related to occupational disease. Current research focuses on developing human cell culture systems for the investigation of oxidant damage to lipids, proteins, and nucleic acids.
Emphasis is placed on the effects of carcinogenic and cardiotoxic industrial chemicals.
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