Danger increases if you drink alcohol or take medicine affecting alertness and reflexes. Dose may require gradual reduction if you have taken drug for a long time. Doses of other drugs may also require adjustment. This medication works better if you attempt to reduce your weight to normal, exercise regularly, restrict salt in your diet and reduce stress wherever possible. Continue taking medicine even when you feel good.
Adverse reactions are usually dose-related and diminish when dosage is reduced.
Carteolol Increased antihypertensive effect. Clozapine Toxic effect on the central nervous system. May decrease antihypertensive effects of guanfacine. Ethinamate Dangerous increased effects of ethinamate. Fluoxetine Increased depressant effects of both drugs.