Gene Expression Lab, NIG Introduction of Gene Expression Lab.
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In this division, genetic backgrounds of the developmental processes are investigated using the fly Drosophila melanogaster and the silk moth Bombyx mori . SCF localyzes to puffs on polytene chromosomes implicating its role in chromatin transtription. Early FTZ-F1 is expressed in blastoderm embryos concomitant with the ftz gene expession. Late FTZ-F1 is only expressed at slightly before each ecdysis and pupation, and has been implicated in the regulation of genes associating ecdysis and metamorophosis. Yeast MBF1 mediates transtriptional activation by GCN4.