The apostles left the Sanhedrin, rejoicing because they had been counted worthy of suffering disgrace for the Name. Now the earth was corrupt in God's sight and was full of violence. God saw how corrupt the earth had become, for all the people on earth had corrupted their ways. You were taught, with regard to your former way of life, to put off your old self, which is being corrupted by its deceitful desires. Pain in childbirth came as a result of sin that came into the world.
Man suffers when working the ground as a consequence of sin in the world.
Their sinfulness led to being unfaithful to God. As a consequence of that unfaithfulness and sin they suffered. Paul suffered because he was bringing God's Word to people who naturally wanted to oppose it. Life in a sinful world will bring many hardships. Man is compelled by his sin to be corrupt and to then corrupt the world.