The amino acids that have been produced in these experiments match those found in modern proteins . Formation of Polymers Accumulation of organic monomers was not a sufficient basis for the initiation of life. Raw material of living systems Formation of polymers was the next step. Prebiont's Proteinoid microspheres aggregates of polypeptides that form when hot aqueous solutions of polypeptides are cooled. Since the aggregates have a boundary between their interior and the external environment the chemical reactions that occur in the interior depend only on the local internal conditions.
Any catalytic activity depends on the microenvironment and availability of reactants.
Self-replication RNA may have been the first informational macromolecule. RNA can function as an enzymatic catalyst Ribozymes Self-replication Zipper chemistry Origins of complex biochemical pathways Naked genetic systems may have been incorporated into nonliving aggregates. Cells must have had some mechanism to handle the release of chemical energy resulting from the breakdown of organic compounds Since all organisms today use ATP as the principle energy currency it is likely that ATP was probably an early evolutionary development. Evolution of Autotrophy Primitive heterotrophs probably developed increasingly more complex biochemical pathways due to competition for diminishing resources. Chemotrophy is the use of energy released from the splitting of the covalent bonds of molecular hydrogen and new bonds are formed This energy could be used to produce organic compounds no longer available in the soup.