Blocked nasal passages, nasal discharge and post-nasal drip are best treated with both a decongestant and an antihistamine. The newer, non-sedating antihistamines do not appear to be as effective in relieving cold symptoms as the older medications in this class. Complications Colds are self-limited. In other words, they always get better, with or without medications, within a few weeks. However, the cold viruses can affect the lining of the upper respiratory system in a way that leads to other infections, such as sinusitis, ear infections or bronchitis.
Cold symptoms are unusually severe or associated with a high fever.
Sinus pain or a toothache develops. Ear pain develops. A cough gets worse, rather than better, as the cold symptoms improve.