Patients with inhibitors require special treatment. F VIII replacement for haemophilia A, no inhibitor.
Dose depends on bleeding severity.
For serious bleeding F VIII assay may be required to monitor response to infusion. Inhibitor assay from the Haemophilia Centre may be important to guide therapy. The Haemophilia Treatment Centre physician chooses which product is best for each patient. Please follow recommendations. Monoclonal antibody purification is used in some concentrates.