After Inferior Alveolar Nerve Axotomy in Rats. Rheumatoid arthritis and related diseases in the temporomandibular joint. After Inferior Alveolar Nerve Axotomy in Rats.
Dental tissues are superior targets for sensory innervation.
The purpose of this investigation was to study the expression of GAP 43 during regeneration of the IAN within the nerve, pulp and periodontium of the first mandibular molar. The study consisted of 8 seven week old Wistar rats. Access to the IAN was made via an extra oral approach through a small bony window at the cannal entrance. At 4 and 7 days subsequent to IAN axotomy the rats were anaesthetized, tanscardially perfused and the jaws demineralized and longitudinally cryo-sectioned. A monoclonal antibody to GAP 43 and a standard ABC technique was used.