Artist Christopher Pratt was the gallery's first curator, in charge of its exhibition and public education activities, and its permanent collection of art. Moving to the St. John's Arts and Culture Centre in 1968, but remaining part of the university, the gallery took on a more active provincial role, organizing touring exhibitions to other arts and culture centres on a regular basis. Over the years, its curators have been Peter Bell, Frank Lapointe and Edythe Goodridge. Patricia Grattan, the current director, became curator in 1982. In 1994, Memorial's Art Gallery became the Art Gallery of Newfoundland and Labrador.
Admission is free.