Tolerance and psychological and physical dependence may develop irrespective of administration route. Those with a history of opioid or other substance abuse or dependence are more apt to respond to euphorogenic and reinforcing properties of morphine and are at greater risk. Withdrawal may occur when morphine is discontinued abruptly or upon administration of a narcotic antagonist. Infants born to mothers using morphine chronically may exhibit withdrawal symptoms. Have naloxone and resuscitative equipment available to reverse narcotic-induced respiratory depression, Also, IV morphine may reduce strength, duration, and frequency of uterine contraction, resulting in prolonged labor.
Epidural use has little or no effect on relief of labor pain.
Increased risk of respiratory depression with use of neuroleptics. The information provided above is based on the manufacturer's official US labeling for this product. Inc. All rights reserved.