Both groups showed a reduction in pain, with those using glucosamine showing marked improvement by week eight. A medical study, conducted on 30 people suffering from osteoarthrosis, revealed the long-lasting effects of glucosamine. The patients took 400 mg of glucosamine sulfate for one week, then one group took glucosamine capsules while the other group took a placebo for the following two weeks. Researchers discovered that those who remained on glucosamine for the entire period improved dramatically, while those taken off the glucosamine regressed, but not to pre-treatment level. Glucosamine helps the manufacture of collagen, the protein part of a fibrous substance that holds your joints together.
Glucosamine helps bind water in the body's cartilage matrixes.
It has been shown to increase collagen and normalize cartilage metabolism, to help keep your cartilage from breaking down. Glucosamine can kickstart the production of cartilage main elements and protect them at the same time. The study divided 212 patients into two groups. One group received 1500-mg glucosamine sulfate and the other a placebo daily for three years. Patients on the glucosamine treatment experienced an improvement in symptoms compared to a worsening of symptoms in those taking the placebo.