Gallstones are the most common gallbladder problem.
Stones, in and of themselves, are not harmful. Many women have them for years and never know. They can become problematic after eating a fatty meal. The gallbladder will try to expel its substances to digest the fats, but end up driving a gallstone into the duct, blocking it instead. When a gallstone becomes lodged in the duct, a woman typically feels a severe, colicky pain on her right side, just under the ribs.