Sildenafil is metabolized or chemically processed in the liver. Medications that interfere with this activity will increase the blood level of sildenafil and result in more side effects. Patients on these medications should only take the 25 mg dose of sildenafil or stop the sildenafil entirely until they finish using these other medicines. There has been no testing or experience using sildenafil with other treatments for erectile dysfunction. Most experts agree that just prescribing a pill is not proper treatment for impotence.
Impotence is often a symptom of an underlying medical condition.
Patients must get treated for any underlying disease. A medical and sexual history together with a physical examination is essential. Blood pressure should be checked, especially in patients on high blood pressure medications. A complete listing of all the medicines the patient is taking should be completed. To better establish the underlying cause of the erection difficulty, other tests may be required.