In DNA sequencing applications, LI-COR instrumentation has become renown for very long reads with superior accuracy.
Infrared detection is the key enabling technology that extends readlength and improves accuracy.
Infrared technology has also increased genotyping accuracy, while reducing the cost per genotype due to lower reagent usage. The NEN Global IR 2 System features LI-COR's unique, two channel detection that eliminates errors due to fluorescence overlap. The two IR dyes used in this system were carefully designed so that their fluorescence is separated by over 110 nm. Two separate sets of optically tuned lasers and detectors independently measure fluorescence signals from the IR dyes. Band detection with no signal crossover also results in high quality genotyping images, similar to an autoradiogram, that are easily and accurately analyzed by genotyping software.