The evidence for multifocal, superficial bleeding, including melena, epistaxis and petechia is consistent with thrombocytopenia. Given the fact that leukopenia is not present, decreased production is an unlikely cause for thrombocytopenia as neutrophils have a shorter life span than platelets. The magnitude of thrombocytopenia associated with splenic sequestration is usually not this low. The normal coagulation factors coupled with the marked reduction in platelet count, is most consistent with immune-mediated thrombocytopenia. The presence of fever is indicative of either an infectious or an inflammatory disease.
Lymphopenia is a commonly observed response in animals distressed by another systemic disease.
Hyperglycemia of this magnitude is consistent with the stress of the disease or sampling. Absence of glycosuria precludes a diagnosis of diabetes mellitus. If the white cells in the urine were simply a reflection of hemorrhage into the urinary tract, only a few white cells could be accounted for. Given the large number of white cells in the urine, there exists a concomitant inflammatory process within the urinary tract. The enlarged prostate on physical examination may be indicative of prostatitis which would be the primary cause for pyuria, hematuria and leukocytosis.