Practically no other natural plant material has been so fully analyzed. There are no solvent residues, natural or synthetic additives or other diluents in Pycnogenol. Pycnogenol has gone through extensive testing at prestigious research centers such as the Pasteur Institute, Huntington Institute, and others over many years to confirm its purity and safety. Within one hour of ingestion, Pycnogenol can be detected in the saliva. The amount varies from person to person.
Larger people can use more.
This means a 150 pound man or woman would take between 100 mg to 200 mg at first to reach tissue saturation. Saturation is reached in 7 to 10 days. Pycnogenol is very stable. Pycnogenol is acidic. It has a low pH of 2.5 to 4.0.