Once an acute condition is brought under control, OD to BID dosing is often adequate for maintenance therapy and reduces the risk of side effects and tachyphylaxis. It is important to apply just enough to cover the affected area. Excess quantities are messy and a waste of money. An excessive fear of topical corticosteroids may result in poor compliance, and sub-optimal therapy. It is important to apply just enough to cover the affected area.
Excess quantities are messy and a waste of money.
An excessive fear of topical corticosteroids may result in poor compliance, and sub-optimal therapy. This usually takes several weeks, but can occur earlier. Tolerance should be suspected if an inflammatory skin condition worsens after an initial good response. Tolerance may be prevented by limiting long term application frequency to once or twice daily. Tolerance to the anti-inflammatory effects of topical corticosteroids can occur.