Studies of cell nucleus revealed co-operative character of levels of the chromatin organisation. Transdifferentiation in development and induction of differentiation in tumours were suggested to involve epigenetic cell selection. Aberrant cell cycle and cell death were found to have common features in embryonic development and tumours. Lysis of cell nuclei on perforated electron microscopic supports. - Microsc. Erenpreisa et al.
Apoptotic chromatin favours aggregation and fluorescence quenching of DNA dyes.
Erenpreisa et al. Image analysis of differentiating chick embryo chondrocytes. Erenpreisa et al. Influence of single-strand DNA breaks on ultrastructural and cytochemical organisation of the tumour cell chromatin. T Arshavskaya, Je.