It's an example of how even the most esoteric of research can have commercial potential. The economy is thriving. The Internet is growing at a frenzied rate. This special issue also contains advice for would-be entrepreneurs and guidance from experienced physicists who've been in business for years. There's no point burning yourself out when others can do the legal, marketing or financial work better than you.
Communications skills are also fundamental.
You can't expect to raise finance from venture capitalists if you can't explain your technology in a nutshell. You don't even need to have years of experience to establish a business. But particle accelerators themselves are full of technological opportunities for business, including photomultiplier tubes and superconducting magnets. The time is ripe for going into business. But the financial rewards are high and there's the thrill of seeing your idea becoming reality.