Certain blood types are more prevalent in the population, thus more easy to match with potential donors. The converse is also true. If a your serum displays a high degree of reactivity when screened against a panel of random donors, then prior to any transplantation your blood would be cross-matched with that of the potential donor to reduce the likelihood of acute rejection. Again, blood group typing is the most important factor in determining the likelihood of finding a donor. High serum reactivity could make this process more challenging and possibly extend the waiting time, but is in no way an insurmountable barrier to undergoing successful cardiac transplantation.
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