Axons from these exit the spinal cord, pass over the apex of the lung and synapse in the superior cervical ganglion of the sympathetic chain in the neck. The postganglionic axons from these course from the neck to the eye with the internal carotid artery via the cavernous sinus. Fibers from these axons form the long and short posterior ciliary nerves of the eye. Dilates a normally innervated pupil by inhibiting re-uptake of norepinephrine at synaptic terminal. Localization Indirect-acting sympathomimetic.
Forces release of endogenous norepinephrine from pre-synaptic vesicle.
Lymphadenopathy Sinusitis Footnotes 1. Clinical Optometric Pharmacology and Therapeutics. Anisocoria and abnormal pupillary light reaction. Clinical Decisions in Neuro-ophthalmology. Evaluation of the causes and accuracy of pharmacologic localization in Horner's syndrome.