However, all of these features are seen only when the disease has been present for many years. Most patients present with pain only. All of these conditions have to be considered and appropriate diagnostic tests applied. The juices are analyzed for their content of bicarbonate and certain enzymes. Simpler versions of this test using test substances given by mouth and collecting blood or urine are less sensitive.
Chronic pancreatitis is confirmed by x-ray tests and other scans.
Ultrasound and CT scans can show enlargement and irregularity of the pancreas, and areas of scarring. This shows the tissues of the pancreas, but also the duct systems in more detail. Endoscopic ultrasound is another technique used to detect more subtle and early changes of chronic pancreatitis. This will show any area of blockage, stone or duct irregularity. Juices can be collected from within the pancreas for laboratory analysis.