On the second day, we first tested performance in the same CW field to identify drug effects on motor performance and recall. Immediately afterwards, subjects were exposed to the CCW field in order to test drug effects on learning novel dynamics. Motor learning of CCW was followed by another recall test of the CW field. We found that subjects in all groups were able to learn the first CW field, and that none of the drugs disrupted recall or motor performance of this field on the second day. In contrast, they significantly affected learning of the second CCW field.
Further analysis is under way to determine differential influences on learning.