Wear protective clothing. Avoid inhalation of these materials by evacuating and ventilating the area. Stable under normal conditions. Repeated exposure to the skin can result in dermatitis. Highly volatile liquid.
Acute toxicity is low.
However, survival was significantly improved in all exposed groups compared to control animals. Tumors occurred late in life and none were assessed to be life threatening. Tumor formation is thought to occur through non-genotoxic mechanisms associated with a peroxisome proliferating potential or with hormonal disturbances in older rats. Rodent studies indicate HCFC-123 is easily absorbed via inhalation. It distributes in all organs, more so in the liver.