The entire trip takes about 7 hours with an outboard motor, or 9 days by canoe. Numbered markers guide you through mangrove forests, through Whitewater Bay, and around countless islands.
Campsites are available along the route.
A backcountry permit is required for overnight camping. Permits may be obtained at the Flamingo or Gulf Coast Visitor Centers. Nautical charts are necessary for finding your way in the coastal zone, and are useful in planning your trip. They may be purchased from area stores. A launch fee is charged for non-motorized boats.