A wolf hybrid will make a better guard dog. Due to the shy nature of wolves, hybrids usually make poor protection dogs. Aggressive tendencies, if any, present in the hybrid may be fear induced and, as such, can be unpredictable and hard to control. A wolf hybrid will live longer than a dog. The life span of a wolf in captivity is 12-14 years, the same as a large dog.
Hybrids are healthier than dogs, and are less prone to disease.
Wolves and dogs are prone to the same infectious diseases. There may be some question as to the efficiancy of standard dog vaccines in wolves and some hybrids. Huskies and malamutes are part wolf. Alaskan Malamute's are the most closely related to wolf. As in there ancestry to be domesticated as pets .