The nucleus is the information centre of the eukaryotic cell. It synthesises the mRNA for thousands of proteins in a highly regulated manner. It also replicates its entire structure accurately once, and only once, during each cell division cycle. This course starts by considering the dynamic architecture which allows the nucleus to perform these functions.
Later lectures discuss how the genetic information is stored, accessed, replicated and read.
Functional elements needed for chromosome replication 4. Replication forks, repair and cell cycle control 5. Promoters and general factors 9. The prokaryotic nucleiod and its structure. Consequences of the lack of a nuclear membrane for gene regulation.