Beveled pipettes penetrate tissue and impale cells more easily.
Cells impaled by a sharpened, beveled tip suffer less damage and remain viable longer.
They also give a more linear electrical response. This beveler offers the additional advantage that the beveling process can be monitored as grinding progresses, and the pipette beveled to a target impedance. The grinding is done on a flat glass surface with alumina powder for grit. The alumina powder is wetted with a salt solution and grounded with a wick electrode if impedance is to be monitored. The Omega Tip Z Megohmeter is specifically designed to measure electrode tip impedance in electrolyte filled glass micropipettes, or fine tipped metal electrodes.