We can only come close with mathematically knowing it. Scientifically we describe data with a model, getting closer and closer to reality but never reaching it. We often mistake symbols for reality. When you are setting up a model you can never prove that the model is good or that it is true. You can disprove but never prove a scientific model.
Indigenous belief supports the idea that everything is related.
Science seems also to be proving that now. S M-We now have a prediction that supports that idea but cannot prove it. We are hung up on our scientific and mathematical models. M-In science there is a critical mass of evidence that proves a model but we can never prove beyond the shadow of doubt. We can show relationship.