Intraventricular chemotherapy thro ommaya reservoir may be tried. It depends on the duration and the patient's immunity status. Without treatment it is a fatal disease. Endemic in south west united states most cases are sub clinical. Most common in males and agricultural workers.
Focal symptoms are uncommon, chronic meningitis is common.
X-rays reveal radio lucent lesions with minimal or no new bone formations. Thoracic and lumbar spines are commonly involved. The disc is relative spared and contiguous ribs may be involved. Body collapse occur only in late cases, Para spinal masses and sinus are common. Amphotericin B in the mainstay.