The lines of Nicolas and Werner Weisel have been documented in Friedberg beginning in 1308. Whether all present day Hessian Weisel descendants are descended from one common ancestor or family is unknown. The number of Weisels still in this area of Germany are not large, given that 6 centuries have passed since the name came into existence. In 1999 there were 70 Weisel listings in the German telephone book for the 35xxx zipcode area. The 35xxx zip code includes Butzbach, Eberstadt, Gambach, Nieder Weisel, Hoch Weisel, Lich, Muschenheim, and Muenzenberg.
Further research needs to done.
Additional data needs to be collected from the 1300s into the 1600s from the four areas of Upper Hesse listed above. The spelling of German surnames was not standardized until the 19th century. In Germany during the late middle ages, most people, including the nobility, could not read and write. In this era there was no correct spelling of a name. People didn't possess a passport or official document for identification.