Thus, increases the effect of the dopamine which remains in a Parkinson's brain. Reduce need for levodopa. When given with levodopa, enhances and prolongs response to levodopa. Decrease action of the enzyme COMT, which normally destroys levodopa. Thus, increases the amount of and prolongs the action of levodopa, which is converted to dopamine.
Dopamine reduces the symptoms.
Used alone to help control tremor and rigidity, or with levodopa. Reduce or delay the need for levodopa. Very limited use. You can search this site or check New Drug Approvals or Drugs in the News for updates or more recent information. For more information or details concerning this topic or specific drugs, try searching this web site .