Antigens are proteolytically processed from the cytosolic compartment by the proteosome and trafficked through the endoplasmic reticulum and loaded onto the Class I molecules. Four epitopes were found derived from three secreted proteins, LLO, p60, and Mpl. Also, add, that live, hemolysin minus mutants do not protect. I pathway of antigen presentation. Since epitopes are all derived from secreted proteins, dead bacteria do not secreted the antigens.
Growth is important to generate the appropriate cytokine respone.
All of the above.