However, the SP cost changes whenever any gap is introduced for all positions which follow the code letter being optimized. For this reason sequence alignments optimizations are done backwards, starting with the terminal amino acids, after a cost or similarity matrix has been constructed in a forward fashion starting beginning with the starting amino acids. Top Many multiple alignment dynamic optimization techniques require to selection certain parameters. The choice of such selection may influence the outcome of the optimal alignment. Gene identification with Microarrays.
Genetic research creates information at an exponential rate.
High Throughput Screening tests numerous chemically synthesized compounds each month using DNA or gene microarray technology. Excellent introductory reviews of microarray technology are provided by Leming Shi Ph.D. and by Jerremy Buhler . More and more data are added to data bases. Medical researchers, involved in clinical trials, collect data on drug response effectiveness in patients and publish their data. More databases are added but likely to different types of databases.