Therapy Studies Systemic drug therapy of malignant pleural mesothelioma. Ricerca sul Cancro, Division of Medical Oncology I, Genova, Italy.
Few patients are possible candidates for radical surgery.
The role of chemotherapy in the management of pleural mesothelioma still remains uncertain. The results of combination chemotherapy are comparable to those of single-agent chemotherapy and no major difference is detectable among the various combinations. Prospective phase II trials are recommended for the identification of new active treatments while large-scale randomized phase III trials are needed to identify the best available treatment. In addition, new standard criteria for eligibility and response assessment are required. Click here to order or save article If you have any questions regarding treatment options or your legal rights, please contact us .