Pathology in the brain is similar to the optic nerve. An autosomal recessively inherited syndrome of retinitis pigmentosa, deafness, obesity, and diabetes mellitus. The retinal lesion causes nystagmus and early loss of central vision in contrast to loss of peripheral vision first, as in other pigmentary retinopathies. So, it is in the differential diagnosis of optic nerve disease. Alzheimer's Disease Dementing brain disease in which visual field defects of optic nerve damage can be demonstrated.
Chromosomal inheritance is implicated.
Also, some studies suggest a preferential maternal inheritance implying a mitochondrial genetic role in Alzheimer's Disease. Most amacrine cell types lack an axon. There are about 40 different types. Amaurosis A general term for partial or total blindness especially referring to retina or optic nerve degeneration. Usually temporary loss of vision due to temporary blood supply deficiency to retina or optic nerve.