The euchromatin is believed to be primarily in the 30nm chromatin fiber form. These fibers are further organized into large loops. However, it is not randomly dispersed. Although interphase chromain appears to be uniformly distributed, the chromosomes are actually arranged in an organized fashion and divided into discrete functional domains that play an important role in regulating gene expression. The chromosomes are closely associated with the nuclear membrane at many sites.
Individual chromosomes occupy distinct territories within the nuclei .
Cell Cycle G1 - period between last mitotic division and start of DNA synthesis. Active period of gene transcription. Makes sense - don't want it to be too condensed for transcription and replication. Metaphase chromosomes represent the most condensed phase. Important because it allows the chromosomes to be faithfully segregated into daughter cells.