However, most anti-HIV medications also cause problems in the digestive system. Clarithromycin could make those problems worse. Clarithromycin can be hard on the liver. Your doctor will probably watch your lab results carefully for any sign of liver damage. Let your doctor know if your urine gets dark or your bowel movements get light-colored.
Antibiotics kill some helpful bacteria that normally live in the digestive system.
You can eat yogurt or take supplements of acidophilus to replace them. Clarithromycin is broken down by the liver. It can interact with other drugs that also use the liver. Scientists have not yet studied all the possible interactions. Be sure your doctor knows about all the medications you are taking.