Nowhere is this more evident than in the characters of Niles and Frasier. The actors' timing is perfect, and the styles of Kelsey Grammer and David Hyde Pierce are complementary. The result is a seamless symbiotic relationship. Melanie's Tourette's syndrome and Cage's verbal tics, along with the quirkiness of the two, have combined to create wonderful chemistry. On rare occasions, an entire ensemble can stir up chemistry.
Image is important, but it's the dialogue that generates a visceral response in viewers.
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