You will not lose any information, but your summary data will not be accurate.
Frequent backups are a good way to avoid data loss in the event of monitor failure.
High moisture corn can increase the error rate on your yield monitor. To minimize these inaccuracies, change your M1 value for corn from 790 to 650 and change your S1 value from 75 to 50. Therefore, you will not need to perform extra calibrations for a new grain type, as you will be using the same grain type for all corn. Grain weight calibrations are probably the most important calibrations you will perform on your yield monitor. Use relatively equal sample sizes of at least 3000 lbs.