In 111 patients suspected of having photo-allergic dermatitis, photopatch tests to FM were performed. Over 12 study years, there was an increased trend for reactions to fragrances, particularly in males. The most sensitising components of the fragrance mix tested in 38 patients were cinnamic alcohol, oak moss, and cinnamic aldehyde . There were 112 immediate patch test reactions to FM and 113 to BP in 664 patients. This represented a significant increase in the frequency of delayed contact reactions.
Fragrances commonly cause both delayed and immediate patch test reactions.
Patients with immediate contact reactions have an increase in delayed contact reactions to the same allergen. Katsarou A et al . Contact reactions to fragrances. Following 3 treatment courses, the extract of allergens was taken again to make intradermal injections . The diameter of redness and swelling on the skin was significantly reduced in comparison with that before treatment.