There are a number of options that you might come across that land elsewhere in America. You then transfer to an internal flight to Orlando. There are pros and cons to this system. If you land elsewhere you would do custom and immigration at that airport - it might be faster or more pleasant. The cons are that the journey takes longer - you sometimes have to wait a couple of hours for your onward flight to Orlando.
International flights are Nonsmoking.
The cabin staff will remind you that smoke alarms are fitted in the toilets. Carry -on luggage is now restricted by most International airlines. Try to keep hand luggage to a minimum. Scheduled airlines have a more generous luggage allowance than charter flights. I read that the airlines release the cheapest seats first.