Dogs living in homes with very high outdoor currents nearby were nearly seven times more likely to develop lymphomas than control dogs. Osteosarcoma Bone tumors in dogs are very similar to those in humans. These tumors are usually high-grade, aggressive, and usually spread to other parts of the body. The lung is most commonly involved. Osteosarcoma tends to affect larger breeds with a slight increase in incidence with age.
Males are more likely to be affected than are females.
And since neutered dogs and bitches have twice the risk of developing the disease as compared to intact dogs, hormonal factors are thought to play a role. Weight-bearing long bones of the legs are most frequently involved, especially the metaphysis of the radius. Breeds which weigh over 80 pounds are 61 times more likely to develop bone cancer than dogs weighing less than this amount. Also, the rates of developing bone cancer between breeds increases with standard height of the breed independent of the dogs' weight. This means, for example, that when you consider two breeds which weigh over 80 pounds, say an Irish Wolfhound and a mastiff, the wolfhound has a higher likelihood of getting osteosarcoma because he is taller at the withers.