These effects may include hot flashes, mood swings, headaches and vaginal dryness, and are reversible upon cessation of treatment. Patients may experience bone loss during prolonged medically induced menopause. Studies have shown bone loss to be reversible after treatment stops, and may be prevented by use of calcium supplements. Allergic reactions may occur in some women. Although generally appearing as a localized reaction at the injection site, any type of welt, itching, or redness should be reported to the doctor.
Animal studies showe no evidence of cancer.
Women should use barrier contraception during the entire course of GnRH agonist therapy. Lupron is not indicated for women who are pregnant or are trying to become pregnant while using the drug. GnRH agonists offer a way of altering reproductive hormones to treat conditions that are hormone dependent. Therefore they lessen many of the symptoms of uterine fibroids. A growing body of scientific evidence is showing that Lupron can safely and effectively treat a number of women's reproductive disorders.