A man on hormone replacement therapy will use it for the rest of his life, in the same way that women taking estrogen do. Once a man is on replacement therapy, it's important to monitor his testosterone levels, says Booth. A man may feel better at first, but if his levels get too high he could become aggressive and angry. In fact, monitoring testosterone levels every five years is a good idea for all men 35 or older, says Shippen. The reason to do testing in younger men periodically is to establish baseline levels when they're healthy.
Doctors can then compare levels as men get older and make sure no significant drops take place.
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