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Cells frequently respond to environmental changes or insults by undergoing apoptosis.
Apoptosis is an essential component of the organism's repertoire of cellular responses, whether it is triggered by a genetic program for development or induced by an external factor. Most assays for apoptosis are not readily adapted to HTS, however. Promega has recently developed a useful marker for apoptosis that can be added directly to cells in culture. The simple add, wash and analyze format makes this apoptosis marker easily adaptable for use in high-throughput screening systems. Go to the Promega Notes current issue index .