Weedone CB was tested and found not to be an affective control of bigleaf maple due to rapid resprouting by the tree. Lindgren, B.S. 1986. Trypodendron lineatum breeding in bigleaf maple, Acer macrophyllum . The striped ambrosia beetle, Trypodendron lineatum which is found breeding in hardwood species like Alnus, Betuls and Malus , was found to successfully attack and breed in the bigleaf maple. Nadkarni, N.M. 1985.
Epiphytes growing on the branches of Acer macrophyllum rely on the tree for structural support.
The bigleaf maple in turn produce canopy roots that tap into the thick epiphytic mats for nutrient resoucres. Anatomically the roots are similar to their belowground counterpart including mycorrhizal association. Simultaneous stimulation of endophytic Crytodiasporthe hystrix and inhibition of Acer macrophyllum callus in dual culture. It is believed that water-soluble metabolites produced by the callus may be responsible for this effect. Sieber, T.N and Dorworth, C.E. 1994.