This dice pool is then rolled against the difficulty of the attack. For a punch, the difficulty is 6. If you score at least one success and the target does not get more successes if they dodged, then you hit. Damage for everything but guns is strength based. Melee weapons will have a damage rating that is added to your strength as does things like a kick, claws or a bite.
Firearms are a bit different.
They are also much more lethal than most brawling or melee attacks. The number of successes rolled is added to the weapons damage rating and that is rolled for damage. For example, if Mongo is attacking Tinkerbell and she decides to shoot him with her pistol, scoring 4 successes. Mongo decides not to dodge, gambling on her missing. She would then add the gun's damage rating, in this case a 4 to her 4 successes and then roll 8 dice damage.