The Dielectric Properties of Water within Model Transbilayer Pores. To whom all correspondence should be addressed.
Ion channels contain extended columns of water molecules within their transbilayer pores.
The dynamic properties of such intra-pore water have been shown to differ from those of water in its bulk state. This result is discussed in the context of electrostatic calculations of ion permeation through channels, and the effect of the local dielectric of water within a helix bundle pore is illustrated using a simple Poisson-Boltzman calculation.