The cardiomegaly is not associated with fat accumulation, or with lysosomal storage. There are increased cardiac muscle mitochondria, but this is a non-specific finding. The kidney lesion shares features with multicystic dysplasia from urinary tract obstruction, but there is very little evidence of earlier normal nephrogenesis. The bladder and ureters are small which suggests that they were not obstructed. The diagnosis of a known syndrome could not be made, however, there is a high probability of a genetic abnormality, and recurrence is possible in a subsequent pregnancy.
Genetic counseling is recommended.
They will eventually be uploaded along with the case to the database, but I have yet to get last issues cases uploaded. Registration details can be obtained from Dr. Ona Faye-Petersen who has spent really countless hours organizing it, and tracking down exciting speakers. I like writing off the wall editorials, whether anyone reads them or not. I like sending slides for which no one knows the diagnosis. I like having a meeting about placental pathology without a constricting agenda.