The commitment to a hybrid or a wild animal is a major one in comparison to a domestic animal. As with canid hybrids, having an approved vaccine for rabies for felid hybrids is another concern that the veterinary community feels needs to be addressed. Even with the best of preparation, the challenges associated with hybrid ownership go far beyond the average pet owners skill and tolerance. Most hybrid animals will have unique socialization and rearing needs to give them an edge to adapting into a new household. There is still no guarantee that they will adapt.
Hybrids tend to weigh more and to be much larger than the average cat.
Often they are much more developed in their musculature and strength. The evolution of each species of exotic feline has produced unique and specialty animals. True domestication takes thousands of years to accomplish and our domestic cats are thought to have been companions to man about half the time that dogs have. Human interference into this process focuses on specific traits that make our domestic animals amiable to living with or working for us. In only the best situations are they selectively bred for both strong physical and psychological traits.