Extensive traumatic injuries can cause the release of the protein myoglobin from ruptured muscle cells, which may cause acute kidney failure. Heat stroke, severe exercise, drug overdose, infection or excessive alcohol intake also can activate the release of myoglobin. Contact with certain heavy metals or various solvents can induce acute kidney failure. Multiple organ failure. This type of diabetes is the leading cause of kidney failure, accounting for 35 percent of new cases each year in the United States.
Hypertension can injure the kidneys, impairing their functions.
Kidney damage is more likely to develop in people with type 1 diabetes than in people with type 2 diabetes. But because many more Americans have type 2 diabetes, type 2 diabetes is the most common cause of end-stage renal disease in the United States. Complications Few of your body's systems aren't affected when chronic kidney failure occurs and leads to uremia - a toxic buildup of wastes in the blood. The primary goal of treatment for acute kidney failure is to reverse the primary cause of the injury if possible. Treatment then focuses on preventing any ongoing injury to the kidney and replacing kidney function by dialysis.