Estrogen therapy may cause uterine bleeding or breast pain. If you take certain other drugs while using estrogen, the effects of either could be increased, decreased, or altered. Steroids such as Deltasone Tricyclic antidepressants such as Elavil and Tofranil Special information if you are pregnant or breastfeeding Return to top Estrogens should not be used during pregnancy or immediately after childbirth. Use of estrogens during pregnancy has been linked to reproductive tract problems in the children. If you are pregnant or plan to become pregnant, notify your doctor immediately.
Estrogens decrease the quantity and quality of breast milk.
If this medication is essential to your health, your doctor may advise you to discontinue breastfeeding until your treatment is finished. After starting your therapy, the doctor will prescribe a higher dose if necessary, but should try decreasing the dose or discontinuing the medication every 3 to 6 months. The usual starting dose is one 0.05 milligram patch applied to the skin 2 times a week. The usual starting dose is one 0.5 milligram patch applied to the skin once a week. The usual starting dose for all uses is one 10.3 milligram patch applied once a week.