If pain crisis is also present, admit the patient for I.V. hydration and observation. If patient is dehydrated or has severe vomiting or diarrhea, admit for intravenous fluid therapy to prevent pain episodes or other complications. Outpatient management includes administration of clear liquids, Coca Cola, ginger ale, bismuth subgallate 400 mg PO t.i.d. PC, and vistaril or phenergan for nausea. Admit for intravenous therapy, support and observation. Admit if anorexia and vomiting prevents hydration and caloric intake.
Enteric isolation is indicated and prevention for recommendation for contacts.
See weekly in follow-up if not admitted. Admit immediately and monitor carefully. Patient will need aggressive transfusion, close monitoring, and treatment of complications. Admit to I.C.U. for aggressive transfusion and close monitoring - Pyelonephritis . Admit for intravenous antibiotics.