Both grow rapidly and extend to structures beyond the thyroid. Both small cell and large cell carcinoma present as hard, ill-defined masses, often with extension into the structures surrounding the thyroid. Small cell anaplastic thyroid carcinoma must be carefully distinguished from lymphoma. This tumor usually occurs in an older age group and is characterized by extensive local invasion and rapid progression. Five-year survival with this tumor is poor.
Death is usually from uncontrolled local cancer in the neck, usually within months of diagnosis.
Lips CJ, Landsvater RM, Hoppener JW, et al. PDQ statements exist for a number of topics. Please consult the PDQ Index . This document is also available in a text-only format . The information provided through OncoLink should not be used for diagnosing or treating a health problem or a disease.