Don't be hasty in removing damaged plants. It might surprise you how quickly they recover once spring arrives. It's the time of year when oak leaf blister will start spreading it's spores. Treatment will need to start as soon as leaf buds swell in order to prevent spots from forming on your oak trees leaves. Neutral copper is labeled as a control for this disease if it is applied soon enough and correctly.
Large trees are impossible for a homeowner to treat.
You will need professional help. Three treatments spaced ten days apart are needed and there is really no guarantee that sprays will solve the problem. Oak leaf blister does not kill trees. You have probably met a click beetle. There are some 500 American species.