The Jean Hailes Foundation, Clayton, VIC, Australia. Baseline measurements were similar in the two groups. These findings persisted after correction for age and sex. Dietary supplementation with soy-derived phytoestrogens improves lipid profile and blood pressure but not measures of vascular function in both men and women. This may offer a therapeutic dietary intervention with minimal side effects to reduce cardiovascular disease, especially in men in whom estrogen therapy is inappropriate.
Further research is needed in high-risk hypertensive and hyperlipidemic populations.