When the results between the two harvestings were compared, it could be seen that the antimicrobial action of sodium hypochlorite and castor oil was significant for streptococci. Papaine did not show a significant result. Due to its antimicrobial action, the castor oil plant solution can be a substitute for sodium hypochlorite as an irrigating solution for root canals. Papaine gel has not been assessed as an antimicrobial agent particularly in endodontic treatment. Our results lead to the conclusion that the action of papaine gel did not show efficiency similar to the other solutions evaluated.
Further studies are necessary on the proteolytic action of papaine gel on necrotic pulpal tissue.
All three irrigating solutions showed antimicrobial action. At the first harvesting, the anaerobic microorganisms were present in a greater number followed by the streptococci and S. mutans. Histologic and histometric evaluation of rat alveolar wound healing around polyurethane resin implants. Health and safety aspects of working with enzymes. The 1991 Lindberg Award.