This page is part of a frame-set. All these features which contribute to the definition of prognostically important sub-groups will be included in a new classification system currently under consideration. Median age at diagnosis is 50 years. Rarely presenting symptoms are due to chloromas or CNS involvement.
Cytoplasm shows variable basophilia.
A few granules or Auer rods may be present. Maturing granulocytes may be normal or show the dysplastic features seen in MDS . Monoblasts are generally very large with abundant grey-blue or basophilic cytoplasm. Nuclei are round or lobulated, and are central in the cell. Fine azurophil granules may be present but Auer rods are rarely, if ever, present.