Empty it out completely. When you empty the area, group like items together. Use the floor, boxes or bins to group items as you remove them from their old home. Designate a place for everything. Keep the groups large.
Complicated systems are almost impossible to maintain and discourage compliance.
Clean the area and install protective liners, coverings or materials. Choose shelves, bins, tubs, and other organizers for your groups and install them. Restock the area. Minimize reach distance. Consumables can be stored up high since they don't need to be put away later.