GFAP promoter directs astrocyte-specific expression in transgenic mice.
Fatal encephalopathy with astrocyte inclusions in GFAP transgenic mice. Mice lacking GFAP are hypersensitive to traumatic cerebrospinal injury. Astrocyte-specific expression of tyrosine hydroxylase after intracerebral gene transfer induces behavioral recovery in experimental Parkinsonism. Mutations in GFAP, encoding glial fibrillary acidic protein, are associated with Alexander disease. J. Neurosci .