Those several features of the disease make gene therapy unlikely in near future. Early detection of disease may lead to the early treatment with effective measures. It is also characeritized by recurrent episodes of abdominal pain, protracted malnutrition, ketosis resistant diabetes. Ten per cent patients with tropical calcific pancreatitis develop pancreatic cancer. Almost one third of patients with tropical calcific pancreatitis get recurrent episodes of pain in childhood can develop diabetes in childhood.
Dense calcification is seen in pancreatic parenchyma.
Though exact aetiology of tropical chronic pancreatitis is known, malnutrition with protein deficiency, cassava toxicity, impaired immune response, viral infection and genetic susceptibility have been considered as various factors in the aetiopathogenesis. Hypertriglyceridaemia and hyper parathyroidism though rare reported to have chronic pancreatitis in children. Unusual case of chronic pancreatitis was eight years old child presenting with progressive distension of abdomen without pain. This patient had haemorrhagic ascites with markedly elevated ascitic fluid amylase. Patient was started on lipid lowering agent and remarkable improvement in the symptoms.