Effect of chronic use on CNS is unknown, although patients have received recommended dose for up to 15 courses. Steroids may or may not be effective in controlling these episodes. Majority of patients rechallenged developed a recurrence in hemolytic process. If eyes are affected, rinse thoroughly with plain water. Take precautions in patients at risk.
Drug can induce response as early as first week of therapy.
Immediately wash skin or mucosa with soap and water, or rinse eyes thoroughly with water, if accidental contact occurs. Drug may cause fetal harm. Safety and effectiveness not established. Adverse Reactions Frequent reactions, regardless of incidence, are italicized. Reactions include those seen in an MDAH study of 101 patients given fludarabine.