It was found that oral vitamin D is effective in reversal of serum calcium, phosphorus and alkaline phosphatase to the normal levels, as well as the radiological abnormalities seen in long bones of rachitic infants within one month of daily treatment. Increased plasma alkaline phosphatase was found to be a constant finding in vitamin D deficiency rickets and it is the last parameter to return to normal after initiation of therapy and indicates definitive healing. Infants under two years of age are those who are liable to have vitamin D deficiency rickets, particularly if they are exclusively breast fed with no exposure to direct sunlight. The higher the level of education of the mothers, the less likely is the chance that their infants will become rachitic. The well-educated mothers will use all medical facilities offered by the society.
Family size is an important factor, which leads to how much care is given to individual children.
Vitamin D deficiency rickets can present with a wide variety of symptoms, the most important of which are recurrent chest infections and seizures. It was recommended that rickets be looked for as an underlying cause for these complaints. An elevated level of serum alkaline phosphatase is a constant finding in vitamin D deficiency rickets, and is the last biochemical parameter to return to normal after initiation of treatment and indicates complete healing. Oral vitamin D preparations are effective and safe in treating vitamin D deficiency rickets when given in proper doses and for a suitable duration. Performance of kits used for clinical chemical analysis of calcium in serum.