The human body is unable to convert diosgenin from wild yam into the hormone DHEA or progesterone. Though the conversion can be done in the laboratory using chemicals, there has not been evidence to support the human body doing so. Products claiming to contain natural progestereone usually in a cream designed for topical application contain USP, a pharmaceutical grade of progesterone. It is not always apparent from the container just how much progesterone is being added and whether the progesterone is pharmaceutical grade or made from plants which may not provide actual progesterone at all. However, creams made from plants and hormones are easily absorbed through the skin and taken directly into the bloodstream and is very effective for many women.
Hot flashes can deplete B vitamins.
Panothenic acid nourishes the adrenal glands. Hot flashes increase one's need for B vitamins. Vitamin E can reduce hot flashes, balance mood swings and prevent vaginal dryness. Vitamin C clears heat and nourishes the adrenal glands and is needed for collagen production so that our skin remains elastic and supple. Bioflavonoids have a chemical activity similar to estrogen.