Low melatonin levels are associated with a lessened immune response as well as depression. It is thought that our immune system interacts with melatonin at night. One to five tablets thirty to forty-five minutes before bedtime. Contains no preservatives, sugar, starch, salt, wheat, yeast, corn, milk, soy derivatives, artificial flavoring or coloring agents. Many biological functions are rhythmic such as the short rhythms of breathing and heartbeat.
Longer patterns are common, such as monthly menstrual cycles and annual seasonal cycles.
By changing the length of time we are exposed to varying intensities of light during a day, it is possible to affect the timing of melatonin production and disrupt our sleep patterns. This can be experienced with jet travel. As we traverse several time zones, our production of melatonin gets out of sync with the new time causing jet lag. Also, if one's job requires them to work different shifts, it can take days to get used to the new time resulting in feeling tired most of the time. Understanding circadian rhythms can be meaningful.