Next, reinforce litter box use by offering favorite food treats for appropriate behavior. This let's your furry companion know just how much you appreciate good potty manners. It takes vigilance and patience, but positive reinforcement really does work. And finally, keep the litter box clean to encourage consistent use. Dirty boxes simply won't get used, so don't set your pet up to fail.
Experts recommend removing soiled litter and adding clean litter at least once or twice a day.
You should completely empty and wash out the box once a week before refilling it with your litter of choice. Special Ferret Advice Veterinarian and author, Karen Purcell, DVM, recommends teaching ferrets to use the litter box when they first wake up in the morning by placing them in it and not letting them out until they've deposited their waste. She warns that ferrets are smart enough to learn to fake it by backing up and giving a convincing performance, so be sure to check for actual results before rewarding the behavior with a treat. If you overwhelm her with too much freedom before she's ready, she will forget where her box is and will lose her good habits. The Society also warns that it takes as little as three days to break a good litter box habit, so keep watch that little mistakes don't become bigger problems.