The medicinal use probably originated with the Khoi and Nama people, who used extracts externally to wash wounds and internally to relieve fever and a variety of other ailments. Infusions of the corm have traditionally been used as emetics to treat dizziness, bladder disorders and insanity. Extracts have been given to weak children as a tonic and the juice is reported to be applied to burns. The stems and leaves are mixed with other ingredients to treat prostate problems. Traditional uses are also said to include the treatment of testicular tumours, prostate and urinary infections.
Aloes still form an important ingredient of commercial laxatives.
Aloe ferox and other aloe species are used to a great extent in traditional human and livestock medicines for the relief of arthritis, eczema, conjunctivitis, hypertension and stress. It is also applied externally to relieve skin irritations, bruises and burns. The leaf juice of this plant relieves infections of the mouth and throat. It is also taken orally to treat dysentery, digestive problems, tuberculosis and as a diuretic and styptic. It is highly astringent and is applied externally to treat eczema, wounds and burns.