Any combination of intermediate and finished product should maximize output of finished sequence. Focus finishing efforts on gene-rich regions. Solve the long-range contiguity problem for finished sequence in 2 or 3 years. Achieve intermediate product coverage of the remainder of the genome by the end of 2001. Obtaining a tiling path is unsolved, and is a critical problem.
Cost analysis is critical.
Must achieve 24 million reads to accomplish goals 1,4, and 5. There was general agreement with this proposal. Rather, the draft should be considered as a useful by-product that will emerge because of an improved strategy for finishing. Thus, the definition of the draft should not be too rigid at this point. However, lack of definition raises a concern that the draft will not be of good quality.