The 46 chromosomes introduced into the egg are identical to the genetic material contained by all the other adult cells of the donor that contain 46 chromosomes. Therefore, the moment that 46 chromosomes are introduced into the enucleated egg is equivalent to the naturally occurring point of conception. In cloning, the life created will be genetically identical to the donor, as though it were an identical twin of the donor. During development, in both the naturally conceived and the clonal embryos, repeated divisions of the embryo continue to increase the number of cells until they then begin to specialize and organize into an adult. Specialization during development is called differentiation.
Differentiation is a continual process.
Specifically, as the cells multiply and divide, groups of cells become gradually committed to particular patterns of gene activity. Differentiation does not mean that cells lose genes during development. In fact, all differentiated adult cells of an individual are genetically identical. They are simply not metabolically identical. This means that different genes are activated to make proteins as required by the individual cell.