I saw an interview with the comedian George Burns when he was 98 years old. He said his greatest joy in life was that he did exactly what his heart lead him to. The success, financial and otherwise, followed. I can see these will really vary depending if you're white collar or blue collar. Deadlines and 70 hour weeks were the sort of problem I had.
Management makes all the difference.
I always enjoyed my co-workers. I was a workaholic myself, but I always overcomplicated everything, and could never prioritize projects well. With every job I've ever had, there has always been at least one co-worker that makes me not want to go to work. Miaow Depends on what sector and industry you're in, and at what level. I personally would add lack of inspiration and lack of sense of ownership in projects.