All drugs are expected to be found in bound or unbound state. Never assume that receptors are fixed and stable. Can change affinity or receptor number. Hydrogen bonds and Vander Waals Forces lock it into position. TOP Cellular Foundations A. Forces across membrane .
Identical particles move apart form high concentration to low.
Like forces repel. B. Factors that influence neurotransmitter release Transport of neurotransmitter down axon. Electrically excite pre-synaptic membrane. Organelles in nerve terminal synthesize or store neurotransmitter. Post-synaptic receptors channel opening and closing.