Critical to take the time to do this, Just Call, Inc. has software that enhances this process. The tighter the keywords and the page integrate the better. Even this doesn't always work, many search engines don't read frames properly, if you must navigate using frames, create an opening or splash page that will help draw people into your site, an provide a page for search engine spiders to work with. Also, negotiate reciprocal links with other complimentary sites. Plus, this is a good way for your customers to become better educated.
Links are the key to the internet.
Play it safe and repeat less or not at all. Yahoo for example, only allows a 200 word description. Avoid submitting a page that uses meta-refresh faster than the eye can see. The content of the page needs to correlate with your keywords. If you choose to use an automated computer program to submit, choose carefully.