Oral medications have a long history in spasticity management. Oral drugs are usually the first type of medication prescribed for spasticity. Effective spasticity management may require a combination of two drugs, or the use of an oral drug with another type of treatment such as chemodenervation. In addition to the information presented below, you may view the product inserts for these drugs by clicking at the left.
Benzodiazepines reduce spasticity through their action on the central nervous system .
Both short and long-acting benzodiazepines are used for spasticity management in adults and children. Diazepam is the most commonly used. The benefits of benzodiazepines may include improved passive range of motion , less muscle overactivity and fewer painful spasms, as well as general relaxation. Benzodiazepines are often preferred for use at night, since drowsiness is a common side effect . Some patients also experience unsteadiness and loss of strength.