A negative picture of ourself and what we can achieve. Blame ourselves or accept blame when it's not our fault. The type we see in this story. Guilt is knowledge that what we have done is not right and a sense of personal responsibility for this action that we will be held accountable for. It causes physical problems.
Guilt can bring on severe depression.
It can cause one to lose all perspective on reality. Talk about how you have experienced these in your own life. Talk about it.