Enteroviral illness is typically benign.
During the summer and fall enteroviruses may account for the majority of fevers without an apparent focus in infants. A wide variety of rashes occur in association with enteroviral disease, but only 'hand, foot, and mouth disease' is sufficiently characteristic for diagnosis on clinical grounds alone. Patients with epidemic pleurodynia experience spasmodic and paroxysmal chest pain, often without other symptoms or objective findings. This syndrome is commonly confused with other causes of chest pain. Myopericarditis is usually sporadic, and typically presents with dyspnea, chest pain, fever, and malaise.