This will cause crashes. Actually, it's my opinion that 100 or more towns is probably too much anyway. The special node which destroys all items in a rectangle doesn't work right. It only destroys items in the upper left corner. One designer has gotten nasty crashes trying to have a special encounter triggered by Ritual of Sanctification.
Blades is very liberal with what it considers a creature which counts towards the maximum total.
Conveyor belts don't move items correctly. If the player opens a save file inside a town with conveyor belts, the belts sometimes won't move items on them. The Affect Webs node doesn't seem to work right. The values of Extra 2a for Change Horse Possession and Change Boat Possession special nodes are backwards. Outdoor Move Party, DO NOT move the party to within 4 spaces of the edge of the outdoor section.