Fragrances are known to modify cerebral blood flow. In spite of this most fragrance materials have never been tested for neurological effects. Synthetic musk compounds bioaccumulate in human tissue and are only slowly excreted. The systemic and long- term effects of most fragrance materials are not known. There are environmental concerns as well.
Fragrances are volatile compounds and some of every fragrance product used gets into the air.
Given the widespread use and sheer numbers of products used this has a serious impact on indoor air quality. Not only is indoor air impacted, outdoor air is as well. Air is not the only concern as synthetic musk compounds contaminate aquatic environments and wildlife all over the world. There are other concerns as well, which are impossible to cover in a short amount of time and space. Br J Dermatol.