Marble and porphyry facings sheathe the walls of the single-nave church and elaborate, colored marble inlay covers the floors. The eyes of the visitor are drawn toward the raised presbytery where the small miracle-working icon of the Virgin stands, enshrined on the altar. At the time of the Miracoli's construction, other Venetian churches contained some marble paneling, but no other church in Venice was completely clad in marble from the outset.
Documents indicate that the interior marble facings originally reached up to the first cornice.
The upper register of the walls was probably decorated with stucco painted to imitate marble. The decorative scheme called for the light-colored panels to be placed into frames created by darker borders. The panels in the upper half are much larger, their veining differs significantly, and no vertical or horizontal harmony can be established between the two zones. The conditions resulting from this situation necessitated the now completed restoration, which has returned the Miracoli to its original splendor. As one enters the church through the main portal, one stands beneath the balcony.