The inclusions, exhibiting ground-glass nuclei, margination of chromatin, nuclear molding, and multinucleation, are typical of herpes simplex virus.
Herpes esophagitis with ulceration and granulation tissue.
Herpes esophagitis can be seen in both immunocompetent and immunocompromised patients. While not required for diagnosis, in situ hybridization is being performed on the previously submitted material and will be reported separately.