My grandmother had lupus. Lupus is not a true genetic disease and is quite rare. However, many patients have a relative who has had the disease. African American and Hispanic women are at greater risk-two to four times that of Caucasian women.
Hormones are also a factor.
Estrogen predisposes to lupus. Estrogen production decreases as women age, and thus, in menopausal women, the disease is less common and less severe. Lupus is a chronic, autoimmune system disease, which means the body's defense system attacks itself and lacks the ability to fight off infection. Lupus can manifest in a range of ways, from minor or vague to serious and life threatening. If you suspect lupus, see a rheumatologist for a complete evaluation, including family history.