It is characterized by a skin rash, followed in weeks to months by central nervous system, cardiovascular system and joint symptoms. The majority of people who get Lyme disease do not become seriously ill. Named for Lyme, Connecticut, where it was first described, it is often confused with juvenile rheumatoid arthritis of children. Many patients report a tick bite at the site of the lesion 3 days to 3 weeks prior to the rash. In the US the white-footed mouse is the primary host and animal reservoir for the nymphal ticks and the spirochete.
Deer are an important preferred host for the adult ticks.
Other mammals such as dogs can be incidental hosts and can develop Lyme Disease. There may be multiple papules. Fever and chills. Stiff neck and headache Nausea and vomiting. Enlargement of the spleen and lymph glands.