In a recent study, subjects with CHD were given breakfast cereals containing three different amounts of folic acid, in addition to B6 and B12. Plasma folate increased and plasma homocysteine decreased in relation to the folic acid content of the cereal. A recent report by the Institute of Medicine stated that all adults, not just women of childbearing age, should consume 400mcg folate per day. Bendich et al developed a method for translating published risk reduction estimates based on vitamin intake into estimates of potential savings due to avoidable U.S. hospitalizations. If clinical trials confirm data suggesting these and other conditions can be ameliorated with other vitamins or mineral supplementation, healthcare savings could be significantly greater.
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