Whenever we over-indulge physical appetites and passions, we impair our mental processes and judgments as well as our social relationships. Our bodies are ecosystems, and if our economic or physical side is off-balance, all other systems are affected. That's why the habit of sharpening the saw regularly is so basic. The principles of temperance, consistency and self-discipline become foundational to a person's whole life. Trust comes from trustworthiness and that comes from competence and character.
Intemperance adversely affects our judgment and wisdom.
I realize that some people are intemperate and still show greatness, even genius. But over time, it catches up with them. Either we control our appetites and passions, or they control us. With age, the metabolism changes. Maintaining health requires more wisdom.