Exostoses grow throughout childhood, but usually ossify at the end of skeletal growth.
When they grow large they are frequently painful and can disturb growth resulting in variable short stature and deformity. Less commonly, neurological and vascular symptoms can occur when exostoses affects adjacent nerves and vessels. Disease severity can range from mild to severe even within families. Surgery to remove problematic exostoses is often required during childhood. Inheritance patterns Autosomal dominant.