In a Normal trial, the entire range of one crystallization matrix is used, and every crystallization drop in the trial is composed of crystallant plus the same set of other solutions, e.g. the same macromolecule formulation. In a Complex trial, the crystallization conditions used do not have to span the entire range of a single matrix , and crystallants from many different crystallization matrices can be used. Also, the crystallization drops in a Complex trial do not have to use the same macromolecule or additive solutions. To set up a Complex trial, select the Complex radio button in the Welcome dialog window of the New Trial Wizard , and click Next . The Attributes dialog window for a Complex trial looks much like that for a Normal trial, except that there is no field to specify the crystallization matrix.
Complex trials are limited to a single crystallization apparatus.
Any plate in the database can be used, but the trial may use only one count of the selected plate. Click Next to proceed to defining the crystallization conditions. The Copy Well dialog window allows a new crystallization matrix to be created from any crystallization condition in any of the available matrices. From the Select Source Matrix pull-down list box, select an available matrix. The other side of the dialog window shows the template for the selected crystallization plate, in this example, a 24-well Charles Supper plate.