Our ultimate goal is to manipulate stem cells to replace degenerating photoreceptors in the human retina. Soluble factors and the development of rod photoreceptors. Extraocular mesenchyme patterns the optic vesicle during early eye development in the embryonic chick. The nuclear receptor transcription factor, ROR b , regulates retinal progenitor proliferation. Multipotential stem cells and progenitors in the vertebrate retina.
Hedgehog protein promotes rod photoreceptor differentiation in mammalian retinal cells in vitro.