Females should be spayed when they come into season or they will die. Prolonged estrus is deadly to ferrets. They're not like dogs or cats and will continue to be in season until something is done. Hormone injections may not bring your pet out of season, spaying will. Descenting is an option but not necessary.
Intact ferrets have a strong musk aroma.
When they're altered much of the odor disappears. Bathing too frequently will cause the oils to replenish and will cause more odor. Ask your veterinarian for any information they have on ferrets. Ferrets are house companions. There are several types of cages that can be used.