The question of 'how much is that set worth' is one which confronts any collector or dealer each and every time a new set is encountered. There are no hard and firm prices on any historical antique, it's a matter of what you think it's worth and what a buyer is willing to pay. Somewhere between those two extremes exists a number both of can live with. If there is one variable that will greatly change the value of a set it is missing or replaced parts. Those sets made prior to 1870 are more valuable than later sets due to earlier sets are more ornate and have non-metal handles on knives.
Earlier sets are lined with velvet or some similar material, later sets have all wood interiors.
Non-metal handles are early, metal handles are later. Ivory is more desirable than composite handles. Curved blades are earlier than straight blades. Such a set would be one marked for a given surgeon or period and accompanied by documents to prove who the owner was or how that individual was significant. These kind of sets are rare.