Extensive amyloid deposits decrease the function of the tissue. The cause is often unknown.
Cardiac amyloid presents as a restrictive cardiomyopathy or a dilated cardiomyopathy .
The deposits of amyloid protein are localized to the heart tissues. Senile cardiac amyloid is differentiated from other forms of amyloidosis by its localization to the heart. There are no symptoms of systemic amyloidosis, long-term kidney failure , or effects on other organs or tissues. Senile cardiac amyloid is a rare disorder, affecting adults, usually over 50 years old. The disease may be asymptomatic .