There is some evidence that after bone marrow trans-plantation, eye movements subside. No one knows what the optimum dose is but the dose should not be reduced. We do not know if this will help neuro-logical symptoms but it is effective in treating the spleen, liver and bones. There is consistent aggressive disease in the spleen, liver, bones and other parts but considerable variation in neurological progression. Enzyme replacement therapy is the treatment of choice.
Close monitoring is required.
Gaucher's News June 1997.