Generally All patients are affected, but the degree and nature of the handicap varies. No patient can be expected to manage a life without support from other people. Walking function None or minimal. Dependence of wheel chairs or rollators is the rule. Only four patients known today can walk unsupported.
Hearing is affected to a varying extent.
No patients have become permanently blind or deaf. Temporary blindness after stroke-like episodes has been reported though. The ability to talk normal language is in most cases strongly limited, while the ability to understand as a rule is good. Socially Good social contact. The children are good tempered, friendly, positive, and loving.