It has also been shown that steroids may not completely block the effect of leukotrienes.5 These factors may define the clinical role of antileukotriene agents in asthma management. Accolate 20 mg bid is indicated for the preventative and chronic treatment of asthma in adults and children 12 years of age and older. Accolate is not for use in the reversal of acute asthma attacks. Accolate is an oral controller agent available by prescription only. Accolate is taken twice daily, even during symptom-free periods, at least one hour before or two hours after meals.
Accolate tablets are generally well tolerated.
Patients should consult with their doctors before changing their current asthma medications, if they are prescribed a blood thinner, if they are nursing, or if their medical condition worsens. Miyamoto T, AccolateTM Clinical Trial Committee. Comparison of patients with prescribed oral and inhaled asthma medications. Arch Intern Med. Smith L, Hanby L, Lavins Bernard, Simonson S, A single dose of zafirlukast reduces LTD4-induced brochoconstriction in patients on maintenance inhaled corticosteroid therapy.