Amino acid content of human hexokinase 1. This hydropathy plot is shown in Figure 3. Hydrophobic domains are positive values and hydrophilic domains are negative values. Hydrophobic domains are positive and hydrophilic domains are negative. The secondary structure of human hexokinase 1 is further elucidated in the antigenicity plot shown in Figure 4.
Hydrophilic domains are positive and hydrophobic domains are negative.
Since the most hydrophilic domains are the portions of the protein that extend farthest out from its center, these domains are the most likely candidates for effective epitopes. These peptide sequences would be good epitopes against which to generate monoclonal antibodies for human hexokinase 1. Antigenicity plot of the amino acid sequence of human hexokinase 1. Positive values are hydrophilic and negative values are hydrophobic. A prediction of the secondary structure of human hexokinase 1 is shown in Figure 5.