A casino will cheat its patrons whenever it thinks it can get away with it. Slot mechanics and change girls know where the best slots are and can usually tell when one is about to pay off. All slots are basically alike. Winning at slots is just a matter of luck. When the casino sees a player winning heavily, it has a slot mechanic open the slot up and adjust it so it stops playing.
Casinos place their loosest slots in certain locations on the casino floor.
Progressive slots are the best slots to play for your money. You see someone hit a big jackpot with the very first pull of the slot you just left, chances are good you would have hit that jackpot had you made that next pull. It's a good idea to always bet maximum coins at whatever denomination slot you choose to play. Tricks like feeding in coins fast or slow or jerking or jiggling the handle have no effect on the outcome. A slot's reels exist only to show whether you have won or lost.