This may become so severe that any topical application to the facial skin will produce stinging and irritation. Soon afterwards, the redness will progress and cover a majority of the face. Stage III Rhinophyma, the final and most severe stage of rosacea, is rare. It is characterized by swelling and enlargement of the nose, central facial areas, and even the ears. Although rosacea cannot be cured, topical or oral treatment have been proven beneficial in reducing and even alleviating symptoms.
Early intervention can prevent progression in the latter and more severe stages of the disease.
Once the more severe stage is reached, surgical treatment may be necessary. This can be used to remove telangiectasia or correct an enlarged nose. Fewer side effects than the oral dosage form Tretinoin. Decreases the quantity of small blood vessels that had developed under the skin. Metronidazole Antibacterial, Antiprotozoal agent and Isotretinoin have limited use for severe rosacea.