Very social and trainable. Need lots of handling. Can be very active and can easily escape from little hands. Tend to sleep during the day and be active at night. Mice - More tendency for cage to smell than with other small rodents.
Females like to build nests.
Guinea pigs - Less worry for little hands than smaller rodents. Easy to hold and cuddle and are sweet-natured. Love to grunt and whistle. Will usually stay awake during the day. Like to play with their water and can be very messy.