The abnormal smear patter seen in this case led to the discovery of the ovarian tumor and the endometrial polyp. In a postmenopausal woman who is not receiving exogenous estrogen an atrophic cervical smear pattern is expected. The smear shown exhibits complete maturation of the squamous epithelium. The effect varies widely from patient to patient and is not dose-dependent.
Hepatic insufficiency can lead to decreased metabolism of estrogenic compounds.
Estrogenic ovarian tumors, which need to be ruled out in a case such as this. Infections such as Trichomoniasis, which can be diagnosed on the smear. Rarely, squamous maturation is seen in association with cervical or endometrial carcinoma. Endometrial cells are only seen in about one fifth of cervical smears of women of reproductive age. This is usually within the first 10 days of the menstrual cycle.