Gene 199, 111-121. Aspartate 155 of human transketolase is essential for thiamine pyrophosphate-magnesium binding, and cofactor binding is required for dimer formation. Transketolase assembly defect in a Wernicke-Korsakoff Syndrome patient. Wild type strains of Dictyostelium discoideum can be transformed using a novel selection cassette driven by the promoter of the ribosomal V18 gene. Plasmid 36, 169-181.
Conserved residues are functionally distinct within transketolases from different species.
Biochemistry 35, 15865-15869. For questions or comments about this site, please contact the webmaster.