Applications of Reporter Genes. Reporter genes code for proteins that produce a signal that can be easily determined in a complex mixture of other proteins and enzymes. Jennifer C. Lewis, Agatha Feltus, C. Mark Ensor, Sridhar Ramanathan, and Sylvia Daunert of the University of Kentucky discuss emerging bioanalytical methods that use reporter genes to signal the presence of a target analyte. 586 A Color Images for Fast-Scan CV Measurements in Biological Systems.
Many cells communicate by secreting small molecules.
These molecules can be measured using fast-scan cyclic voltammetry and microelectrodes, but the approach generates lots of data on detected species and their temporal changes in concentration. Darren Michael, Eric. R. Travis, and R. Mark Wightman of the University of North Carolina at Chapel Hill describe a procedure for rapidly evaluating large amounts of recorded information from these measurements. Quite a contrast. No chromatography required.