In spite of surrounding folklore, there is no specific limit to the number of cortisone shots that can be given. If it does work, cortisone is extremely effective and not too many shots are needed. Cortisone falls into a group of chemicals called steroids. It is very different from anabolic steroids commonly abused by weight lifters or competitive athletes. The first articular or joint injections are preceded by an aspiration withdrawing joint fluid or blood.
Joints commonly injected are the shoulder, knee, ankle and small joints of the hand and foot.
Most of the injections can be followed by a booster injection 2 to 4 weeks later. These follow the same guidelines as articular injections as far as frequency. An epidural steroid injection is another category. Lumbar epidural injections are a relatively simple technique. Hey are done several inches from the spinal cord and are unlikely to be accompanied by complications except, perhaps a headache.