The reverse order of the paticca samuppada will make the matter clear. Old age and death are possible in and with a psychophysical organism. But birth is the inevitable result of past deeds or kamma. Kamma is conditioned by grasping which is due to craving. Such craving can appear only where feeling exists.
Feeling is the outcome of contact between the senses and objects.
Therefore it presupposes organs of senses which cannot exist without mind and body. Where there is a mind there is consciousness. It is the result of past good and evil. The acquisition of good and evil is due to ignorance of things as they truly are. Thus does the entire aggregate of suffering arise.