These will produce somewhat soft 4x5 film output. If you blow up images from these machines to perhaps a 20x30 inch poster size, the image will be visibly soft from a few feet away. Acceptable for some applications, but not up to many commercial requirements. A couple of these can be had for less than six figures. Do not worry, you do not need scans that large for your slide presentations.
File size incorporates all the variables.
To place a smaller image into a slide simply calculate the appropriate file size needed. If you want to output film for hardcopy, say a 8x10 print. All bets are off. The file size requirements are far more demanding. That places the viewer 3 to 6 times closer than the slide appears to someone in the audience.