The pus inside psoriasis pustules consists of white blood cells. It is not an infection and it is not contagious. A person can have a history of plaque psoriasis for years and then develop recurrent episodes of von Zumbusch. This form can cause fever, chills, severe itching, a rapid pulse rate, exhaustion, anemia, weight loss and muscle weakness. The objective of treatment is to restore the skin's barrier function, prevent further loss of fluid, stabilize the body's temperature and restore the skin's chemical balance.
Imbalances can put excessive pressure on the heart and kidneys, especially in older people.
Because this form can be life-threatening, medical care must begin immediately. People with von Zumbusch pustular psoriasis are acutely ill and often require hospitalization. Bed rest, mild sedation, bland topical therapy, rehydration and avoidance of excessive heat loss can improve the situation. Sometimes antibiotics are prescribed in case an infection is also present. However, in acute cases in which the person becomes exhausted from recurring outbreaks of pustulosis, other systemic drugs may be needed.