Donepezil blocks the chemical breakdown of acetylcholine and thereby increases the levels of the chemical in the brain. Donepezil's unique chemical structure makes it more specific for effects on the brain than other drugs. Although some gastrointestinal side effects, such as diarrhea, nausea and vomiting, were reported, a high percentage of patients treated with donepezil were able to tolerate the drug. Seven percent of patients receiving placebo, six percent taking 5 mg of donepezil and 17 percent receiving 10 mg discontinued the study due to adverse effects. Approximately four million Americans currently suffer with Alzheimer's and it is estimated that number will increase to at least seven million by the 21st Century.
AD is a debilitating, life-altering disease that attacks the brain.
Its primary symptom is progressive memory loss, but difficulties with vision, language skills and emotional control are also common. Any question regarding a medical diagnosis, treatment, referral, drug availability or pricing should be directed to either a licensed physician or to the product's manufacturer.