Even obesity and diabetes mellitus with fatty liver are thought not to progress to cirrhosis. Some other event must occur. Nonalcoholic fatty liver disease generally has a good prognosis, without histologic or clinical progression. Some livers may show increased fibrosis and progression to cirrhosis. Management includes weight loss for obese patients, although this is of unproven benefit.
Anecdotal reports indicate a benefit from ursodeoxycholic acid therapy.
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