Renal damage is also associated with overdose. Nausea, vomiting, weakness and abdominal pain are the early signs of toxicity, occuring within 2 to 3 hours. There is a latent period of 24 to 36 hours before the onset of symptoms of hepatic toxicity. Antidotal therapy with acetylcysteine is most effective within 10 hours following acetaminophen overdose. Do not take more than the recommended dose stated on the package.
Liver damage can occur at higher doses.
Children up to 12 years old should not take more than 5 doses a day for more than 5 days in a row. Adults should not take for more than 10 days in a row. Keep in a safe place out of the reach of children. If you suspect a child has taken an overdose, immediately phone your local hospital or Poison Control Center and take the child to the hospital. Always seek immediate medical help if you have taken an overdose, even if you do not feel ill.