This is a treatable disorder that can see great improvement with behavioral modification and the drug, Clomicalm. Clinical signs of this disorder can vary widely, and include a range of destructive or otherwise inappropriate behaviors, from mild to quite severe. The vocalization is the most common sign, and includes repetitive barking, howling and whining, that may occur just when the owner leaves, or could continue until the owner returns. Destruction includes chewing and digging and may be directed toward furniture, clothing, magazines, papers, or window or door moldings. If crated, some dogs will chew or dig enough to break teeth or claws.
Inappropriate elimination includes urination and defecation, oftentimes anywhere in the house.
Remember, these are due to the high level of your pet's uncontrollable anxiety, and not spite. Since dogs can't control their behavior they should never be punished for it. Verbal reprimands and punishment may actually make your dog more anxious and make the problem worse. Clomicalm is clomipramine hydrochloride, a tricyclic antidepressant which is commonly used in humans. It acts by blocking the reuptake of serotonin and norepinephrine, which are neurotransmitters within the brain.