Since they are substances we already consume and produce in very small quantities in our bodies, glucosamine and chondroitin sulfates have no known significant side effects. The book mentions they may actually help your body repair damaged or eroded cartilage. In other words, glucosamine and chondroitin sulfates strengthen your body's natural repair mechanisms. They can replace what your body fails to make. Glucosamine stimulates the manufacture of collage, which is the protein portion of a fibrous substance that holds joints together.
Glucosamine helps bind water in the cartilage matrix.
It has also been shown to help produce more collagen and also normalizes cartilage metabolism, which helps to keep the cartilage from breaking down. Glucosamine may help in stimulating the production of cartilage and improve joint function. Double-blind studies summarized in the book show repeatedly the benefits to patients suffering from osteoarthritis. It helps attract fluid into the proteoglycan molecules. Chondroitin can protect existing cartilage from a premature breakdown.