Glycoproteins of the ECM include the collagens and a number of structurally diverse, multi-functional molecules, e.g., laminin and fibronectin . Some of these molecules support cell adhesion and migration. They are also important in the 3-dimensional structural organization of specialized ECMs such as basal lamina. Cells of the Connective Tissue Fibroblasts are the most common cells in connective tissue. When inactive, these cells are termed fibrocytes.
Fibroblasts are normally bipolar or spindle shaped cells.
Metabolically active fibroblasts have extensive ER and Golgi. Fibroblasts are involved in the synthesis and secretion of ECM molecules Fibroblasts proliferate and migrate to the sites of wounds where they are involved in remodeling the ECM and contracting the wound. Myofibroblasts have morphologic features common to both fibroblasts and smooth muscle and contain increased actin filaments and myosin. Adipocytes are the primary cell type characteristic of fat tissue. The function of these cells is to store energy in the form of triglycerides.