Regular exercise, bilateral premenopausal oopherectomies all reduce breast cancer risk. Tamoxifen - evaluated in the breast cancer prevention trial. There was an increase in endometrial cancers, though, and there was a significant negative quality of life score. Avoid tamoxifen in individuals with risk for dvt, and also with a history of cva or other cardiovascular diseases. In 1955 the incidence was 45 out of 100,000.
Difference is because of the introduction of the pap smear.
This is the most preventable gynecological cancer. HPV vaccination is not here yet but is being worked on. V. Endometrial cancer - most common gynecological cancer. Average age of diagnosis is 59. Typically present with new onset vaginal bleeding.