The material does not necessarily reflect the current or past opinions of members of the UTMB faculty and should not be used for purposes of diagnosis or treatment without consulting appropriate literature sources and informed professional opinion. Epithelial downgrowth forms invaginations into underlying ectomesenchyme. Changes also occur in the underlying ectomesenchyme forming the dental papilla and dental sac. The underlying dental papilla cells differentiate into odontoblasts which are responsible for dentin production. Lingual to primary tooth, dental lamina gives rise to the enamel organ of the permanent tooth.
Amelogenesis begins adjacent to forming dentin and proceeds to incisal edge.
It also forms the periodontal ligament. B. Derivation of Odontogenic Cysts and Tumors 1. Enamel epithelium of tooth crown 2. Epithelial rests of Malassez - remnants of root sheath which is the epithelial network that guides root formation. Epithelial rests of Serres - remnants of primary tooth dental lamina after formation of permanent tooth lingually.