The spleen and lymph nodes are often swollen and enlarged. The development of other symptoms in SLE varies, depending on the organs affected. Joint pain and problems, including arthritis, are very common. A number of skin rashes may occur, including a red butterfly-shaped rash that spreads across the face. A discoid, or coin-shaped, rash causes red, scaly bumps on the cheeks, nose, scalp, ears, chest, back, and the tops of the arms and legs.
Hair loss is common.
Inflammation of the tissues that cover the lungs and line the chest cavity causes pleuritis, with fluid accumulating in the lungs. The patient frequently experiences coughing and shortness of breath . Heart and circulatory system. Blood clots often form in the blood vessels and may lead to complications. The kidneys may suffer significant destruction, with serious life-threatening effects.