It is important to carry away a working knowledge of names for the parts of the liver. Like tributaries of a river, they flow into bile ductules and then ducts, and finally one large hepatic duct, on the common bile duct. The stones block bile flow and it backs up. The bile, being a digestive fluid, can break down membrane lipids in cases of prolonged contact. Thus, you may get damage and inflammation in the gallbladder, or even possibly damage to bile ducts and canaliculi and hepatic parenchymal cells.
Heme is broken down into bilirubin at peripheral sites.
It is transported to the liver, actively taken up, and conjugated. The conjugated bilirubin is then actively excreted into bile and carried to the gut for excretion. If there is mild damage to liver or blockage of bile ducts, then the liver will still be able to conjugate- it just can't excrete. Thus, conjugated bilirubin will build up. The hepatitis virus is eliminated by soluble antibodies in the blood, although you may need to have antibodies against several different virus components.