It usually shows up in the skin, or in the linings of the mouth, nose, or eye. KS can also spread to the lungs, liver, stomach and intestines, and lymph nodes. At first KS was thought to be a cancer.
Lesions often occur on the face, arms and legs.
If KS only affects the skin, it is not life-threatening. If it spreads to other places, KS tumors can grow large enough to cause serious problems. If KS blocks lymph nodes, it can cause severe swelling of the arms, legs, face, or scrotum. Complications in the lungs or internal organs can be life-threatening. KS can often be diagnosed by looking at the skin lesions.