The incorrect Val products are hydrolysed here, but the correct Ile products are protected. This completely destroyed the editing ability. 26 Other aaRSs also have editing activity, including ValRS, which deacylates errant threonine products. And their statement is merely 'just-so' story telling, lacking even the slightest evidence. It is no substitute for explaining exactly how such an editing site could evolve by natural selection.
Error catastrophe is more likely.
Return to text Fraser, C.M., et al. Return to text Hiroyuki Noji et al. , Direct observation of the rotation of F 1 -ATPase. Same issue, pp. Return to text Loftfield, R.B., Biochem. Return to text Loftfield, R.B. and Vanderjagt, D., Biochem.