M.D. Two medical conditions in women, endometriosis and fibroids, that are thought to be caused by the female hormone, estrogen, are now treated with estrogen. During the menstrual cycle, the inner lining of the uterus thickens to receive a fertilized egg. If a woman does not become pregnant in that cycle, she sloughs off the inner lining of her uterus during menstruation. Endometriosis means that the inner lining of the uterus attaches to other parts of her body, such as her ovaries or the outside of her intestines or uterus and causes severe menstrual pain when she bleeds into her belly and vomiting. Usual treatment is nonsteroidal pills such as naprosyn.
Fibroids are benign tumors of the muscular wall of the uterus that stick out or into the uterus.
They can cause heavy bleeding and they can twist and cause pain. O Gregoriou, N Vitoratos, C Papadias, S Konidaris, D Costomenos, A Chryssikopoulos. Effect of tibolone on postmenopausal women with myomas. Changes in vertebral bone mass and serum estradiol and calcitonin. Depot LA produced marked sustained hypoestrogenemia and significant bone loss with complete recovery 1 year after stopping treatment.