Tobramycin is available in special preparations to treat eye infections, alone and in a combination product. The authors suggest this may have been due to kidney damage related to the drug. Seventeen patients with cancer developed calcium, magnesium, and potassium depletion after treatment with aminoglycoside antibiotics, including tobramycin. Until more is known, people receiving i.v. It makes sense for people taking tobramycin to supplement vitamin K to protect against drug-induced deficiency.
Doctors sometimes suggest a daily intake between several hundred micrograms and one milligram.
Slayton W, Anstine D, Lakhdir F, et al. Tetany in a child with AIDS receiving intravenous tobramycin. Hypocalcemia with hypoparathyroidism and renal tubular dysfunction associated with aminoglycoside therapy. Rhodes EG, Harris RI, Welch RS, et al. Empirical treatment of febrile, neutropenic patients with tobramycin and latamoxef.