Within the lobules, cell clusters are arranged in and about an abundant, finely fibrillar stroma. For the most part, the cellular components have no well organized architectural pattern. At isolated points, clusters of cells are arranged in pseudorosettes with central fibrillar material. The cells vary somewhat in size and shape, have indistinct cytoplasmic borders, and round or oval nuclei with densely clumped chromatin. A small number of cells are in mitosis.
Fresh hemorrhage is abundant in and about the tumor cells.
This tumor has the features of a neuroblastoma with little differentiation and extensive fresh hemorrhage. Neuroblastoma, ganglioneuroblastoma, and ganglioneuroma based on neoplasms of neuroepithelium. Only to separate the benign ganglioneuroma. Histology of neuroblastoma has less prognostic influence than location, age , and presence of oncogenes. A tumor measuring lOx8x6 cm. had extended from within the renal parenchyma to expand the renal capsule.