Ferrets never spray their scent as do skunks. Most breeders neuter and descent kits at 6 weeks of age. If not spayed, females may develop medical problems, which will be discussed later. Ferrets are very intelligent, playful creatures who do their best when their owners interact with them daily. They can be trained to come when called, to sit and beg for treats, and sometimes walk on a leash.
Ferrets have a very thick skin and play very roughly with each other.
It is best to teach your ferret at an early age that human skin is not quite so thick. Training will make both you and your pet happier. The urinary tract of the carnivorous ferret is very similar to the dog and cat in anatomy and physiology. Most ferrets can be letterbox trained. The majority of pet ferrets are neutered very young and do not exhibit sexual urine spraying or territorial marking.