The challenge is to find the hole if in fact it exists. I will say that this is a proposition that can't be overcome.
Human existence is limited to a space between the macroscopic and microscopic.
Knowledge is thus limited by human existence. Much like we can know of electrons but we don't know electrons because we can't see them. Everyone go ahead and punch holes in my ideas. Or agree with me, whatever tickles your fancy. But i like holes better because they're much more challenging.