Be very specific. The enzyme chymotrypsin hydrolyzes proteins. The hydrolysis reaction cannot proceed without this hydrogen bond. Briefly explain how this hydrogen bond assists the amide hydrolysis reaction. Questions 8 - 10 refer to the following.
Drugs are very specific for a particular disease state.
Very briefly explain the molecular events involving cimetidine and the H 2 receptor that lead to blockage of gastric acid secretion. A sketch that clearly explains this concept may be used instead of a written explanation. Explain the chemical origin of the specificity of cimetidine for the H 2 versus the H 1 receptor. Very briefly explain your answer to the previous question. Very briefly explain why organometallic compounds are not commonplace in cellular chemistry.