It is a fact that you cannot really appreciate Malta without driving because the public transport system is rather inefficient and taxis are generally too expensive. Driving is on the left hand side of the road as in Britain.
Maltese drivers have a reputation of driving without too much regard to the rules.
However, driving in Malta is relatively safe and in most cases it's easier to just go with the flow. Many roads are not in a very good condition and some areas have few road markings or signs. Seat belts are compulsory in the front and are recommended in the rear. Parking is a problem in Malta due to a shortage of car parks especially in busy centres like Valletta or Sliema. Petrol is at a reasonable price with stations offering attendant services.