Asymmetric chest, absent ribs, and clavicular abnormalities. Agenesis of corpus callosum, hydrocephalus, hypoplasia of vermis cerebelli, large fontanelles, and seizures. Atrial septal defect and pulmonic stenosis. Cryptorchidism and hypospadias. The syndrome is familial and was originally reported as transmitted as an autosomal recessive trait.
Later findings indicate X-linked transmission.