At the same time, certain complement products are essential to clear CIC's and to stop the cascade of cell damage. Individuals with deficiencies of complement proteins are at greater risk of developing immune-complex disease. CIC's leave capillaries to trigger inflammatory events in target tissues. The Arthrus reaction can be prevented by depleting C3 with Cobra venom . Inflammation Inflammation is the most potent effect of immune defense.
Inflammation is recognized as swelling, pain, heat, and redness in the affected tissue.
Inflammation is produced by immune cells within the tissue, releasing specific mediators which control local circulation and cell activities. The ancient purpose of inflammation is to war on invading microorganisms. Thus, inflammation describes a battle-ravaged tissue. Many of the serious, unsolved diseases of modern civilization are expressions of chronic inflammatory processes. Medical therapy is often directed at controlling inflammation.