It is sometimes used to slow the heart rate in patients with certain abnormal heart rhythms . However, too much digoxin can slow the heart too much or cause other arrhythmias. People receiving digoxin often have their blood potassium levels checked because low levels can increase the risk of digoxin toxicity. Diuretics are drugs that increase production of urine and thereby reduce the amount of fluid in the body. They generally act by increasing the amount of sodium eliminated in the urine.
Folic acid is implicated indirectly in the prevention of cardiovascular disease.
Homocysteine is toxic to the lining of the blood vessels. It also promotes blood clots and oxidation of LDL . Oxidized LDL attracts blood cells that participate in forming the atherosclerotic plaque and is also toxic to the endothelium. Many factors can cause elevated homocysteine including low levels of folic acid, vitamins B6 and B12 . Nitrates have been used in the treatment of angina for many years.