Toxicity Acrylonitrile is classified as moderately toxic by acute exposure through oral intake, skin contact, and inhalation. Symptoms of exposure include weakness, lightheadedness, diarrhea, nausea, and vomiting.
Hazardous gases produced in fire include hydrogen cyanide, carbon monoxide, and oxides of nitrogen.
Carbon dioxide or dry chemical extinguishers should be used to fight acrylonitrile fires. Reactivity and Incompatibility Violent reaction may occur on exposure to strong acids and bases, amines, strong oxidants, copper, and bromine. Violent polymerization can be initiated by heat, light, strong bases, peroxides, and azo compounds. In particular, work with acrylonitrile should be conducted in a fume hood to prevent exposure by inhalation, and splash goggles and impermeable gloves should be worn at all times to prevent eye and skin contact. Acrylonitrile should be used only in areas free of ignition sources.