Tests conducted by the U.S. Department of Agriculture have demonstrated Beefalo's superior protein efficiency. While it has more protein than beef from ordinary cattle, Beefalo has fewer calories and significantly lower levels of both total fats and saturated fats. For more information on this subject, go to the Nutritional Information section Beefalo producers are less likely to use steroids, growth hormones, or excessive antibiotics. While there are no rules prohibiting Beefalo producers from using excessive antibiotics or artificial growth stimulants on their animals, most refrain from doing so because of their heightened concern for the integrity and quality of the meat itself. That emphasis on meat quality is often the reason they started raising Beefalo in the first place.
Beefalo is more convenient because it cooks quickly and cleanly.
It must be melted away. Fat is an excellent insulator, so part of the heat and time needed for cooking normal beef is used to melt the fat. Typically, Beefalo has less external and intramuscular fat, so more of the heat is being used to cook the meat. Less fat in the meat also means less grease and mess to deal with during clean-up. Anything you can do with regular beef you can do with Beefalo.