These words from Matthew Henry make the point that if the Bible is true, it is the most profound message we will hear in this life. On the other hand if it is not true, we can discard every bit of it.
Every subject raised in the Bible is either eternally significant or mere speculation.
If he does, he impacts on every area of our lives. If the Bible is true, sin has deeply affected us. If the Bible is true, the message is that sin carries its own results. Life's misery and the dreadful prospect of death and hell are along its course. We cannot consistently say that we are sinners and be unconcerned about our sin.