The majority of co- carcinogens remain to be identTied. This report also notes that smokers who use riltered or lower tar cigarettes have statistically lower death rates from lung cancer than do cigarette smokers who use nonfiltered or higher tar brands. This reduced risk was also noted for laryngeal cancer. However, cancer death rates for smokers of lower tar cigarettes were still significantly higher than those noted for nonsmokers. Edward N. Brandt.
Individuals vary in their cigarette- smoking behavior.
The cigarette product itself is changing. In this chapter we will consider the tobacco as a raw material, how it is made into cigarettes, the cigarette smoke generation process, the composition of cigarette smoke, physiological responses to cigarette smoke, the pharmacololp- of nicotine as a component of cigarette smoke, and efforts to define less hazardous cigarettes through cigarette smoke modification. Also, consideration will be given to the effects of smake characteristics on smoking behavior and, therefore, on the dose inhaled by man and experimental animals. IMew may stisaulate secretion of mucus in the bronchial tubes and inhibit the action of the cMLO lining them. This has a wide range of phar-cological actions on tissues throughout the bodn especially on the nervous system.