The process of drug development suffers from a lack in throughput capacity in functional screening compared to first stage HTS assays. Thus robotic tools are in need to compensate for this discrepancy. Multi Channel Systems engages in the development of automated multi-channel measurements and parallelization of secondary screening processes in drug development. We are actively seeking product solutions to bridge the gap between the ever expanding number of compound hits obtained by HTS and the lack of fast secondary functional screening methods. Modern cardiovascular and neurobiological research increasingly focuses on speeding up data acquisition and on-line analysis from many cells in vitro.
Experimental setup is easy.
The prepared tissue is laid on the MEA either for long-term culture or for acute recording and after mounting the MEA in the amplifier, measurement of electrophysiological activity can begin immediately without any further adjustments. Download the parameters to the STG via a fast serial communication port, and stimulate your preparation either with an independent isolated voltage- or current source. The Roboocyte is shown, complete with a laptop running the roboocyte software and controlling the hardware components. The MEA60 system and a STG-stimulator were used to elicit field potentials in an acute hippocampal slice. The STG - stimulator series.