What drug is the mainstay of treatment for immune mediated disease. List the clinical signs associated with DLE, discoid lupus erythematosus. Necrolytic migratory erythema Important differentials for autoimmune skin diseases are drug reactions.
Drug reactions can mimic many skin disorders and can result from any drug.
EM is characterized by a distinctive target lesion with central clearing. Lesions include erythematous macules or papules that spread peripherally and clear centrally producing arciform lesions. Plaques, vesicles and bulla can also be seen. Bullous and ulcerative lesions of the oral cavity, pinnae, axillae and groin may be present. Affected animals are systemically ill, febrile and anorectic.