Macrophage - mesothelial adhesion interactions are being studied in both human and murine systems and the group liases closely with the wound healing group , especially in relation to their studies on serosal healing and repair of the mesothelial cell layer and on peritoneal adhesion formation. ARDS Project ARDS is a severe inflammatory and fibroproliferative condition with a high mortality. Fibroproliferation is an essential feature of ARDS and leads to extensive lung fibrosis and increased mortality. Of key importance, this process is reversible and a significant proportion of patients make excellent recoveries despite their degree of lung injury. This group is also closely linked both with the lung and the genetics groups.
Apoptosis induces loss of cytokine receptor expression.
Leukocyte typing Eds S. Schlossman et al. Hypoxia prolongs neutrophil survival in vitro FEBS Letts. Endotoxin reduces maximal oxygen consumption in hepatocytes independent of any hypoxic insult. Inflammatory cell activation in sepsis. The current situation in the U.K. British Journal of Intensive Care.