However, as with all medical treatments, there are potential problems which may occur. Medication Risks a. Although mild bruising and soreness are possible with any injectable medications such as those used for IVF, allergic reactions are very rare. When severe, ovarian hyperstimulation can lead to dehydration, large amounts of fluid accumulation in the abdominal and lung cavities, blood clotting disorders, and kidney damage. Occasionally, IVF cycles are canceled to prevent hyperstimulation.
Controversial studies link ovarian stimulation drugs to the development of ovarian cancer.
Although studies are contradictory, some researchers have reported an increase in borderline ovarian cancer in women who use injectable gonadotropins. Until further research is available, careful use of ovarian stimulation drugs is reasonable, but it is also important to note that achieving pregnancy reduces the lifetime risk of developing ovarian cancer. Egg Retrieval a. Ultrasound-guided, transvaginal egg retrieval is a procedure whereby a long, thin needle is passed through the vagina into the ovary. Although women are under sedation or local anesthesia, this procedure can cause mild to moderate discomfort.