Ions are accelerated by a constant kinetic energy source and directed into a flight tube of known length. The velocity of the ionized particles varies inversely with their masses. The start time is triggered by the laser pulse and the time measurement is stopped by the impact of ions on the detector. The detector sends a signal to the digitizer for conversion. As a new service, we are offering direct analysis of peptide digestion mixtures.
Direct analysis is performed using a portion of the total digestion mixture.
For those proteins not identified, we strongly suggest primary structure characterization of one or more peptides by the PDTC's Microchemistry Group . Our turn around time is 48 hours. This service offers optimal analysis of sample with different matrices and several concentrations. 1000-1200 or better can be obtained in the reflector mode. Determination of mass accuracy and resolution is highly dependent on sample properties.