He said the cases of polio in Sindh had been localized as it was present only in Karachi and Northern Sindh which includes Dadu, Larkana and some parts of Sukkur, where 31 polio cases had been reported, whereas southern Sindh had already achieved zero polio level. Mr. Ehsan said although the NDI has ended, but it will be made a sustainable exercise in Sindh and before the start of Ramzan, the administration would concentrate on Karachi in its anti-polio efforts in view of the fact that this city has its own peculiar problems. Promising HIV Vaccine Target Joan Stephenson, PhD JAMA Vol. Furthermore, within 4 weeks, the virus was forced to mutate its tat gene to such an extent that all of the original infecting virus was replaced by SIV with a mutated tat gene. The findings suggest that early in infection, the immune system mounts an assault that the virus is unable to tolerate without changing its genetic makeup.
Animal studies are under way.
This approval extends the indication for Menjugate to now include active immunization of children from 2 months of age and up. Menjugate was previously approved for children older than 12 months, adolescent and adults in the UK in March 2000 and in Ireland in August 2000. The vaccine will be supplied to health authorities in the United Kingdom and Republic of Ireland, which will subsequently distribute the vaccine to general practitioners and vaccination centers in order to immunize infants, children and adolescents as part of the UK and Ireland's extensive immunization program. The Republic of Ireland launched its vaccination campaign on October 3, 2000. With full approval for use in infants through adults, Chiron will begin seeking mutual recognition approval for Menjugate in additional European countries.