Vitamin E in doses of 800 units per day has been used as part of the treatment strategy in both ulcerative colitis and Crohn's. Miscellaneous Conditions of the Gut Lymphocytic colitis is a poorly understood condition in which patients present with diarrhea as the major clinical manifestation. Biopsy of the colon shows the epithelial cell layer to be infiltrated by lymphocytes. In most instances the disease is self limited and treatment with sulfasalazine may be effective in decreasing the symptoms. There may be an association with celiac disease although the colitis is not gluten sensitive.
Collagenous colitis is another variant in which diarrhea is the presenting complaint.
In this condition, there is no important inflammation. Biopsy of the colon shows a greatly thickened collagen layer just below the epithelial cells. It is not understood how this layer of collagen results in the diarrhea characteristic of this condition. There is no specific treatment and again there is frequently a limited course. Bypass colitis is an inflammatory condition that occurs in bypassed colon.