Once a discovery is made in the brain, do an experiment to see if it's right or wrong. Once you know your discovery is right, go to the library to see if your discovery is in some way connected to what has been done and past knowledge. Three, do not write long reviews or books. I violate the third rule once every ten years because I am kind of forced to write reviews. I think Huggins' teaching is right.
Discovery is primarily a brain function.
For discovery in biosciences you don't need a lot of money or equipment. A real good discovery is very simple. Usually one short sentence can state it. Most of the papers in the journals are unnecessary. When you die it doesn't matter how much knowledge you have or how many papers you publish, just what discovery you have made.