Arthritis associated with inflammatory bowel disease. Other - Whipple's disease, Behcet's disease. D. Etiology and Pathogenesis 1. The shared epitope involves the antigen binding site of HLA-B27. HIV may be associated with new onset of aggressive disease.
Articular disease can be rapidly progressive with early onset erosions.
Ankylosing Spondylitis A. Definition - chronic inflammatory disease involving the axial skeleton predominantly but may also involve peripheral joints, entheses and extraarticular organs. 4.Other genetic factors. Prevalence in males and females is likely approximately equal. Peak age of onset late teens to early adulthood. Do not fulfill criteria for any specific spondyloarthropathy.