It bears strong histologic resemblance to reticulated seborrheic keratosis but lacks typical horn and pseudohorn pearls. Hyperkeratosis is rarely present. Treatment is primarily surgical. The development of one nonmelanoma skin cancer predisposes the patient to a higher risk for developing a second. It is therefore recommended that the patient be followed closely for the development of similar tumors at the site of treatment and at alternate locations.
Current recommendations suggest yearly skin exam by a dermatologist.
Options for treatment are similar to those for other forms of basal cell carcinoma and the clinician's choice will likely be case dependent. Recommended treatment options include complete surgical excision or electrodesiccation followed by curettage. Cryosurgery, Mohs micrographic surgery or radiation therapy may be used. In rare instances, intralesional or topical chemotherapy may be useful. All patients should be encouraged to use sunscreens with a sun protective factor of at least 15.