The doctor should also know all medications that the individual is taking. Combinations of drugs may impair thinking at times. The doctor will look for other medical conditions that may contribute to the symptoms. The only sure way to diagnose Alzheimer's disease is to examine brain tissue under a microscope. This can only be done after the person has died.
Brain tissue is obtained by autopsy.
A probable diagnosis is made in a living individual based upon worsening of symptoms typical of persons with known Alzheimer's disease. Occasional memory lapses do not as a rule disrupt daily life. Long-term, progressive dementia results in the continued loss of mental abilities. Ultimately, this makes independent living impossible. A person suffering from the condition often requires nursing home care.