Epidemiology of Johne's disease in Colorado dairies indicates the infection is probably more widespread and of higher prevalence than previously assumed. Studies with ionizing radiation of milk may demonstrate a more effective method for killing mycobacterium paratuberculosis than pasteurization. The abnormal isoform of the prion protein has been demonstrated in follicular dendritic cells and tingible body macrophages in lymphoid germinal centers near the alimentary tract as well as within the vagus nerve. To date, flow cytometric evaluation of peripheral blood mononuclear cells has not detected any of these abnormal isoforms. This work may aid in understanding the pathogenesis of prion diseases.
Antibiotic resistance is both a problem of animal agriculture and human health.
Pantoea agglomerans is known for its ability to produce multiple antibiotics. Genetic mapping is in progress to develop a detailed genetic map of the antibiotic synthesis genes in P. agglomerans C9-1. Numerous horses have been consistently serologically positive for VS without being clinically symptomatic and without any indication of spread among other horses on the same premises. Both of these findings would impact our understanding of the transmission of this virus between animals. Transgenic cattle - Current State of the Art.