Genitourinary malformations were present in 4 children and another had hemihypertr- ophy. Two children were brothers. The other children had bilateral partial nephrectomy or tumorectomy. The two children who died presented with stage IV tumors and high grade malignant. One boy suffers cardiomyop- athy.
All survivors have normal renal function.
With the proven efficacy of chemotherapy, bilateral renal salvage procedures were demonstrated to be effective in controlling disease without compromising renal function or survival. The innovative approaches developed for the treatment of bilateral Wilms tumor may influence the treatment of unilateral Wilms. Gown AM TI - Antibodies to desmin identify the blastemal component of nephroblastoma. Furthermore, there are currently no reliable blastemal markers. Additional studies are required to determine whether desmin immunoreactivity in the blastemal component of WT represents true desmin expression.