Diagnostic value of serum VEGF in women with ovarian tumors. Oehler MK, Caffier H Department of Obstetrics and Gynecology, University of Wurzburg, Germany.
Angiogenesis is necessary for growth and invasiveness of malignant tumors.
Few data are available with regard to serum levels of VEGF in patients with ovarian tumors. We investigated the diagnostic value of serum VEGF in patients with ovarian neoplasms. Statistical analysis revealed significant differences in VEGF serum values of ovarian cancer patients vs. healthy controls or patients with cystadenomas. No difference could be seen between serum levels of healthy controls and women with benign ovarian tumors. Our results suggest that VEGF has potential as a serum marker with diagnostic relevance in ovarian neoplasms.