Saunders C, et al. Setting up a breast cancer family history clinic. Rosenthal TC, Puck SM Screening for genetic risk of breast cancer. A systematic review of genetic polymorphisms and breast cancer risk. Clinical and Epidemiological Information Anti-estrogen resistance in Breast Cancer Breast tumours are initially dependent on estrogens for growth and progression.
Anti-estrogens, particularly tamoxifen can inhibit breast cancer growth.
However, breast cancers frequently develop anti-estrogen resistance. DNA copy number losses at 1p32-pter in monozygotic twins concordant for breast cancer. Deletion mapping of chromosomal region 1p32-pter in primary breast cancer.