Chronic use results in ongoing rhinitis and necrosis of the nasal membranes. Injection of cocaine produces an exhilarating rush. The euphoria passes quickly as the liver rapidly metabolizes the drug. Besides the toxic effects of cocaine, there is also danger of circulatory emboli from the insoluble substances that may be used to cut the drug. Obviously, there is also a risk of serious infection associated with the use of contaminated needles.
Cocaine hydrochloride is dissolved in water.
A stronger base is then added to neutralize the acid content. The solvent rises to the top to be drawn off. As the solvent evaporates, the cocaine salt oxidizes off, laving cocaine base. The greatest danger is that of overdose since a high blood level is quickly achieved. It is so named because it emits cracking sounds when smoked.