Microcephaly, midfacial hypoplasia, flat malar area, prominent occiput, pointed chin, and frontal bossing. Hypertelorism, proptosis with contralateral ptosis, prominent inner canthal folds, epicanthus, and telecanthus. Widely spaced nipples, pectus excavatum, and funnel chest. Inguinal hernia and ascites.
Dermatoglyphic findings consist mainly of simian creases.
Paucity of white matter, thin corpus callosum, hippocampal dysplasia, and abnormal sulcus in the frontal lobe. Necrotizing enterocolitis and abnormal motility. Cholestasis and fibrosis. All reported cases of trisomy 2 are mosaic.