There are global basis sets, using established names for DGauss, and there are a number of special basis that you may want to name in a particular way. Dimensions of the calculation are significantly reduced since only the valence electronic states are of concern.
Computational effort remains nearly constant for atoms in a given column of the periodic table.
Relativistic effects are also included in the pseudopotential description. Pseudopotentials are accessed from the Basis Set dialog and are used for those atoms of a molecule which are in the specified range.