It often complicates chronic murine pneumonia, increasing the death rate. This virus is very unlikely to infect pet mice unless they were acquired from a colony with this infection already established within its members. Nursing mice and those being weaned are the most commonly and seriously infected. Adult mice may become infected but rarely show signs. Signs of the infection include labored breathing, rough haircoat, weight loss and death.
Bacterial infections complicate the picture and usually increase the death rate.
There is no specific treatment for this disease. A commercial vaccine is available but it is only of prractical use with large colonies of susceptible mice. Initial signs include squinting, blinking and rubbing of the eyes. Later, sneezing and swelling in the neck region are noted. Respiratory signs also may occur.