Easy to cure at this point with surgery. WIth malignant carcinoma, crosses basal membrane and invades underlying connective tissue. Chickens could get cancer from a filterable extract of tumors. Translated to make reverse transcriptase. DNA copy made, with duplication of ends to make LTR at each end.
Circular form goes to nucleus and integrates at random location.
Stays there forever. Transcription makes new copies. 35o but not 41o. Temp sensitive mutants due to mutant protein that is unstable at high temps. A certain amount of mutation at this point would give a v-onc surrounded by LTRs.