Everything is mediated - experience has always been totally mediated. The role of mind, body and spirit in interactive art. On the other hand, maybe we just need more resolution and bandwidth. At this stage, there is no serious possibility of humans managing without their bodies. The hyperstructure of the human body CAN be amplified through technology.
Biology is a technology, a meat technology.
Golly, I don't quite see that. So I wonder whether it is a bit too early in the game to worry too much about being replaced by manufactured brains. Meaning is an emergent principle. Rationality is a synthesis of perspectives. These are such classic statements.