Among pediatric patients, vomiting and itching were reported adverse reactions. In subjects given Malarone for prevention of malaria, the most commonly reported side effects were headache and abdominal pain. Malarone should be taken at the same time each day with food or milk. In the event of vomiting, a repeat dose should be taken within 1 hour of dosing. Prophylactic treatment with Malarone should be started 1 or 2 days before entering a malaria-endemic area and continued daily during the stay and for 7 days after return.
Body weight determines the dose for malaria treatment and prevention in children.