They need to be seen by a veterinarian. Xenopus tadpoles are very small compared to other species and will develop best if housed under crowded conditions during metamorphosis. The pH of the water has no effect on Xenopus . They are a hardy species that survive in spite of adverse conditions. Since aquatic frogs have no gills, it is important to be sure that the water is well aerated.
Bubbles seen in the foot webs and under the skin indicate good water oxygen levels for frogs.
When changing the water in cages, water temperature variations greater than 1 C or 2 F can induce shock or even death in frogs. Personnel need not worry about hand lotions, cologne, etc. The protective mucous layer on the frog's skin will make it resistant to toxins, perfumes or oils. Red leg is a term used to describe skin color changes in frogs during breeding season, much like the sexual skin on the rump of baboons. The same water quality standards used for fish should be applied to Xenopus and all anurans.