Play to your strengths, work on those gifts. If you're good at telling jokes, tell jokes. If you're good at wry observations, do that. If you're good at being a friend on the radio, and have an aura that makes folks want to see what it is you're up to, then do that. Meanwhile, a talk show host that has few opinions and doesn't or won't take stands on issues may not belong on every talk station.
Actors have the same dilemma.
You've seen a comedic actor try drama and vice versa, and you know when it's not working. But once you find that niche, you can sometimes milk it for all it's worth. Look at Mike Meyers and his Austin Powers character. Eddie Murphy is talking about a third movie with The Klumps. Likewise, being real with the right audience could mean a long stay at your radio home.