Unlike flow cytometry, the LSC measures multicolor fluorescence and light scatter of cells on slides. The LSC's unique technology also records the position and time of measurement for each cell analyzed. Multiple biochemical, immunological, and morphological measurements are made on each cell. Data is displayed in real time. Cell position is recorded so cells of interest can be relocated, restained, remeasured, and photographed.
Cells remain intact for important assays like fluorescence in situ hybridization.
Telomere lengths measured by the LSC in a recent publication entitled Telomere Shortening Is an in Vivo Marker of Myocyte Replication and Aging . March 9, 2001. Campus Charite Mitte, Berlin, Germany. March 24-28, 2001. American Association for Cancer Research.