All it has done so far is to weaken our immune system and make the bugs stronger. The recent outbreaks of EColi should be some food for thought. It isn't confined to animals only.
Agricultural products can be carriers too.
I sincerely believe that a strong immune system would be much more effective in dealing with mutated microbes than antibiotics. But we have opened the floodgates. It seems obvious that we have reached the point of no return. The mere fact that some persons are more susceptible than others confirms that the human s immune system is what protects the human body from bacterial invasion and frequently uncovers viral stealth. Often a healthy person will not get a strepped throat whereas another person will get miserably ill from a very small bacterial count.