Kuru causes neurodegenerative changes similar to another slow virus disease, Creutzfeldt-Jakob disease , whose distribution is worldwide. Creutzfeldt-Jakob Disease has been found with increased incidence in North Africa where sheep brains and eyes are a common part of the diet. Incoordination leads to severe disability. Tremors and shivering are characteristic findings. Difficulty in swallowing and inability to feed oneself lead to malnutrition or starvation.
Death occurs several years after the onset of symptoms.
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