The microbe usually enters the body through a wound or cut. It can develop after bowel or biliary surgery or in an extremity that has poor blood circulation. When infection begins up to 2 days after introduction of the microbes, localized pain can be intense and accompanied by high fever, marked swelling, skin discoloration, and a watery discharge. Unlike other types of gangrene, this condition does not produce an offensive odor. Potentially a very serious infection, gas gangrene must be treated promptly with extensive surgery to remove all involved skin, subcutaneous tissues, and muscle.
Antibiotics are also necessary.
Antitoxin has not been shown to be effective. Tetanus toxin should be administered to individuals who have not received a tetanus booster within 10 years. Often caused by Staphylococcus aureus bacteria, this condition affects the nodes in the neck, groin, and armpit.