Look for physical signs and symptoms of diseases related to capillary bleeding and fragility. Examples include Cushing syndrome and Marfan's syndrome. Differentiation of Platelet Versus Coagulation Defect Bleeding can be attributable to either platelet problems or coagulation defects. Generally have immediate onset of bleeding after trauma. Bleeding is predominantly in skin, mucous membranes, nose, GI and urinary tracts.
Coagulation system defects.
Observed on exam as hematomas and hemarthroses. Physical Exam Assess volume status and correct shock if present. Do rectal exam for evidence of GI bleeding and examine oropharynx for evidence of bleeding. PTT to assess intrinsic system. May have increased thrombotic events depending on cause.