Nsaids make it much worse or can start them. Acetominophen with narcotic only helps get through a day. Feverfew did nothing. Magnesium some help. Fish oil starts them.
Antioxidants do nothing to help.
Here's one other thing also. Some years ago, in 91, I ate at a fast food restaurant. I went home, woke up early in the morning, had intense diahrrea and pain unimaginable. This persisted for 6 weeks, while they tried to find an answer. I thought it might be food poisoning, they said finally it was IBS, and to eat more fiber.