Prostate cancer can also form in the tissue of the central zone. BPH most often occurs in the transition zone, which surrounds the urethra. Surrounding the prostate is the prostate capsule, a tissue that separates the prostate from the rest of the body. When prostate cancer remains inside the prostate capsule, it is considered localized and treatable with surgery. Once the cancer punctures the capsule and spreads outside, treatment options are more limited.
All male mammals have a prostate, but only humans and dogs are known to develop prostate cancer.