Any insight is highly appreciated.
Prasad Prasad NV Tata, M.Pharm. If the sample will only be used for bioanalytical work, then the concern for interference with clinical tests is removed. Independent of that consideration you want an anticoagulant or preservative that prevents or reduces degradation of the sample in matrix, but that does not interfere with the method used for bioanalytical analysis. For us, analytical methodology and compound of interest drives the choice. When we were using alumina absorption assays for isoproterenol, heparin samples had a broad solvent front.