Topical tretinoin is not recommended during pregnancy. Topical tretinoin has been shown to cause delayed bone development in some animal fetuses. Before using this medicine, make sure your doctor knows if you are pregnant or if you may become pregnant. It is not known whether tretinoin passes into the breast milk. Mothers who are using this medicine and who wish to breast-feed should discuss this with their doctors.
Children are unlikely to have skin problems due to the sun.
In older children treated for acne, tretinoin is not expected to cause different side effects or problems than it does in other age groups. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing use of tretinoin in patients 50 years of age and older with use in other age groups. Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary.