The Columbia Encyclopedia, Sixth Edition. Columbia Encyclopedia World Factbook American Heritage Coll.
Colon cancer is the second most common cancer diagnosed in the United States.
Epidemiological evidence has shown that a diet high in fat and low in fruits, vegetables, and fiber contributes to the development of the disease. Smoking is also a factor in some types of colon cancer. Statistically, a family history of colon cancer or cancer of the female reproductive organs, a history of colon polyps, or a history of ulcerative colitis puts one at a greater risk of developing colon cancer. Colon cancer is most common in people over age 50. Several genes that signal a hereditary predisposition to colon cancer have been identified.