By law, FDA does not have the authority to approve cosmetic products or ingredients, except for color additives. However, regulations prohibit or restrict the use of several ingredients because of safety concerns. In addition, cosmetic and fragrance trade associations have recommended avoiding or limiting the use of some substances.
Contaminants raise additional concerns.
The following is an introduction to special safety and regulatory issues related to cosmetic ingredients. It is the responsibility of the manufacturer and distributor to assure the safety of each ingredient and finished product. The HCP concentration of the cosmetic may not exceed 0.1 percent, and it may not be used in cosmetics that in normal use may be applied to mucous membranes, such as the lips. Mercury compounds are readily absorbed through the skin on topical application and tend to accumulate in the body. They may cause allergic reactions, skin irritation, or neurotoxic manifestations.