Diagnostic work-up of Gait disorder, accompanied by Symmetric polyneuropathy with distal sensory loss . Prominent falling Serum IgM M-protein Demyelination without conduction block on electrodiagnostic studies. This is especially helpful in patients whose neuropathy or gait disorder would otherwise be labeled as idiopathic. The neuropathy may be either demyelinating or axonal . Some immunomodulating treatments, such as intravenous immunoglobulin or cyclophosphamide, may produce improvement in weakness, sensory loss or gait disability.
Corticosteroids are unlikely to be of benefit, even when neuropathy is demyelinating.