Long-term arthritis may destroy a joint and require a total knee replacement . Autoimmune disorders are often treated with medications to suppress the immune system and reduce inflammation. If a tumor or cancer is the cause of pain, surgery, chemotherapy , or radiation therapy may be needed. Side effects depend on the treatments used. For instance, aspirin and antibiotics can cause stomach upset and allergic reactions .
Any surgery carries a risk of bleeding, infection, or allergic reactions to anesthesia .
Pain medication can be increased, changed, or decreased as needed. Someone with an injury often heals with treatment and needs no further monitoring. A person with a tumor or cancer may need regular monitoring for years after treatment. Those with autoimmune disorders may need repeat blood tests to help monitor their disease. Any new or worsening symptoms should be reported to the healthcare provider.