Testicular tumors usually occur in middle aged to older dogs. Metastasis is uncommon. Interstitial tumors do not produce hormones. They do not produce a hormone. Estrogen results in signs of feminization such as symmetric, nonpruritic alopecia with increased pigmentation, gynecomastia, attraction of other males, pendulous prepuce, infantile penis, and bone marrow suppression.
Castration is the treatment for testicular tumors.
Below is a large sertoli cell tumor in the right testicle and an enlarged prostate gland. Estrogen causes squamous metaplasia of prostatic cells with resultant enlargement of the prostate gland. Testicular atrophy occurs in old dogs due to alterations in hormone concentrations. Diseases of the prostate gland Prostatic hyperplasia is an increase in size. It is seen in most intact male dogs over 6 years.