Renal dysfunction may occur. Hematuria and oliguria are common manifestations. Muscular weakness is marked and an ascending CNS paralysis may develop. The patient usually remains conscious. However, delirium and convulsions may occur.
Death usually is the result of respiratory depression.
Induce emesis or perform gastric lavage followed by the administration of activated charcoal. Symptomatic and supportive treatment. Analgesics may relieve the abdominal pain, but monitor carefully for possible paralytic ileus. Respiratory assistance may be needed to insure proper oxygenation and ventilation. The total amount usually required in a course of therapy may range from 4 to 8 mg.