Antigens usually appear within a few weeks of infection and disappear within a few months.
Later, if the virus is activated, the dormancy ends and the antigen level rises. A rising antigen level is typically associated with deterioration of a person's physical condition and may herald the development of AIDS in a person who had been previously asymptomatic. Antigen testing is not yet routinely available and is still being standardized for interpretation. It is beneficial for all addiction treatment patients to know their HIV status, in order to facilitate treatment and to prevent transmission. It is important to confirm the presence of HIV antibodies and presumed HIV infection by taking an antibody test as soon as it is safe and feasible.