Contraindicated in asthma, heart failure, and diabetes. Diltiazem and nifedipine are less effective. More beneficial in migraine with aura or cluster headache. Trial should be .2 months. Contraindicated in heart failure and heart block.
Constipation is a common side effect.
Less effective than methysergide but safe. Should not use longer than 6 months without a 1-month drug holiday to avoid fibrosis. Contraindicated in peripheral or coronary artery disease. Efficacy not shown for migraine with aura. Fluoxetine 10-30 mg PO Qa.m.