It is the second most common cause of cancer death in females after breast cancer, brest, canser. These are some of the major risk factors for breast cancer. Lobular carcinoma in situ is not a precursor of cancer. Ductal carcinoma in situ is a precursor of invasive cancer. Lobular carcinoma in situ is simply a risk factor for breast cancer just like family history of nulliparity.
Atypical hyperplasia increases the risk about four to eight-fold.
Family history of premenopausal bilateral breast cancer increases your risk about four-fold. Age at first pregnancy increases the risk of breast cancer about two to four-fold. If you delay your first pregnancy beyond the age of 30, that Obesity increases the risk slightly. This is probably due to the fact that fat cells have a higher circulating level of estrogen than do nonfat cells. Prior history of ovarian or endometrial cancer increases the risk two to four-fold.