All animals were observed daily for mortality and external signs of toxicity. No significant toxicological differences were noted between treated and control groups. An uncertainty factor of 100 was used to account for the inter- and intraspecies differences. An additional UF of 3 was used to account for an insufficient data base, since the existing data base does not indicate that a second mammalian chronic bioassay will be more sensitive by an order of magnitude. The critical study appears to be only of fair quality and is given a low rating.
Additional studies are supportive and of fair to good quality.
Therefore, the data base is given a medium rating. Medium confidence in the RfD follows. This assessment is not presented in any existing U.S. EPA document. Not available at this time. MRID No. 00064815.