Many researchers believe that if the disease had not been detected through screening, they may have never been diagnosed. Therein lies the dilemma. Once a diagnosis is made, physicians generally have an ethical obligation to treat. These features are often indicators of treatment success and some of them direct treatment decisions to more or less intensive protocols. N-myc amplification .
Amplification means that more than one copy is found in the cell.
A normal cell has 46 chromosomes. This is the ratio of catecholamine metabolites found in the urine. Neuron-specific enolase, a serum marker. This is an enzyme specific to the sympathetic nervous cells from which the neuroblastoma derives. Serum ferritin .