Window and door openings can be provided by some manufacturers. Drywall can be provided already mounted by some manufacturers. Facings are added on-site. Use panels that have structural grade adhesive linking the cores with the facings. Panels can be used as infill in a post and beam structure.
Caulk guns are a necessity.
An oversized saw is useful for cutting panels. If openings are not factory supplied, a chainsaw can be used. Expect to use a large assortment of straps and reinforcing brackets. Stack panels so that the sequence of removal accommodates the order they need to be erected. With MEPS this is most quickly done with a router and a hot knife in the corners.