The disorder may be caused by brain injury, severe brain infections, genetic brain diseases, or developmental malformations of the brain. In some cases, no cause can be found. There may be periods of frequent seizures mixed with brief, relatively seizure-free periods. The prognosis for individuals with Lennox-Gastaut syndrome varies. There is no cure for the disorder.
Complete recovery including freedom from seizures and normal development is very unusual.
These studies are aimed at finding the causes of these disorders, improving the diagnosis, and developing new medications and other therapies. The Neurological Disorders, vol. Dictionary of Medical Syndromes, 4th edition, J.B. Lippincott Co., Philadelphia, pp.