Purity is also an important factor as contamination may render the vaccine worthless by destroying antigenic properties. Other adverse effects may include abscess development at the site of inoculation, or the introduction of an entirely different disease problem. Outdated Vaccine Outdated vaccine may not contain the required antigenic properties due to deterioration or other factors. It is not worth taking a chance that it may work. The investment to obtain fresh, quality vaccine far outweighs the possibility of losing just one animal due to poor vaccine.
All vaccines have limitations.
Some vaccines for certain diseases occasionally do not cause production of enough immunity at both the local and systemic levels to give adequate protection against that disease. We must not expect more than the vaccine manufacturer indicates. It is imperative that vaccines be stored and used exactly as directed by the manufacturer. Exposure to sunlight, chemicals, drugs, and adverse temperatures may destroy the vaccine's effectiveness. Vaccine that requires mixing should always be used promptly.