It was constructed by clustering all complete protein sequences in SwissProt. The novelty of ProDom is that the modular arrangement of proteins has been taken into account and whenever domain boundaries were detected the sequences were cut to produce consistent families of domains. No advance permission is required. This work was supported by grant P41-RR02188 from the NIH Biomedical Research Technology Program, National Center for Research Resources. The file contains over 8.6 million records dating back to 1966.
Coverage is worldwide, but most records are from English-language sources or have English abstracts.
Some Information is retrieved from the original literature. It covers the whole range from yeast to human. It covers the whole range from yeast to human. E. Wingender, J. Biotechnol.