The overall design is not carefully thought out. The statistical aspects are not given sufficient consideration. Approach lacks imagination or originality. Controls are either inadequately conceived or described. The number of observations proposed is unsuitable.
Available equipment is unsuited to the research.
Investigator appears to be unfamiliar with pertinent literature or methods, or both. Investigator's previously published work in the field does not inspire confidence. Investigator relies too heavily or insufficiently on experienced associates. Investigator needs more contact with colleagues in this or related fields. Current research grants held are adequate in scope and funding to cover the proposed research.