Inflammation from this disease is very painful. Flare-ups are frequent and long lasting. The initial area of attack is the membrane that lines the joint.
Cartilage is the joint's cushion that covers the ends of bones allowing free movement.
Over time, it breaks down cartilage as well as the ligaments, muscles, and bones. Rheumatoid arthritis causes overall stiffness and aching. It tends to affect more than one joint. Smaller joints such as the wrists, hands, feet, or ankles are the most common sites for this condition. The hips, knees, or elbows may also suffer.