Good prognostic signs include a high total lymphocyte count and the ability of the patient to mount a delayed hypersensitivity response. The overall survival of endemic Burkitt's lymphoma is dependent on the initial stage of the disease. Patients with localized disease respond well to chemotherapy and have an excellent survival rate. Patients with disseminated disease respond less well to chemotherapy and have a poor survival chance. The limited medical resources in Africa also limit the survival of these patients.
Chemotherapy is the treatment of choice.
The high growth rate of the tumor renders it sensitive to chemotherapy with a rapid response in some cases. However, relapses are frequent. Sporadic Burkitt's lymphoma occurs throughout the world. It usually occurs during the first two decades of life. Males are affected more frequently than females.