There is fine interstitial fibrosis in the myocardium. This is an example of alcoholic cardiomyopathy of the type that does not respond to thiamine therapy. Gastrointestinal tract Acute gastritis has already been mentioned. Typically blood is not present initially. Major blood loss may result.
Alcoholic cirrhosis is associated with an increased occurrence of chronic peptic ulcer.
Cirrhosis and early varices also present. Chronic duodenal ulcer which was associated with extensive terminal haemorrhage. Male alcoholic aged 50. Other autopsy findings included early cirrhosis, bilateral pneumonia and mild acute pancreatitis. The pathological manifestations include generalized cerebral atrophy, cerebellar atrophy with loss of Purkinje cells and changes of Wernicke's encephalopathy.