Our laboratory focuses on the analysis of the diversity of the human B cell repertoire and its changes in the responses to self and foreign antigens, and in the establishment of B cell neoplasia. B cell counterparts. Organization of human immunoglobulin genes. Each CH gene is shown as a single box but is composed of different exons.
Asterisks indicate nonfunctional pseudogenes.
Quantitation of precursors of antibody-producing cells and generation and characterization of monoclonal IgM, IgG and IgA to rabies virus.