Includes mathematical modeling to describe physiologic function, to understand pathological, conditions, and to design bioartificial organs, mechanisms, and cellular behavior. Introduction to the nervous system is given including the electrophysiology of nerve and muscle cells, synaptic transmission and sense receptors. The theory underlying Hodgkin-Huxley type models of excitable cells is discussed and several examples of models for neurons, muscle cells and synapses are used as case studies. Modeled neurons are interconnected using synaptic models to form functional representations of small neural networks. At all levels comparisons are made with experimental data.
Course provides an introduction to biological modeling and computation.
Emphasis will be placed on issues regarding design and synthesis of materials to achieve specific properties. An overview of significant biomaterials application will be given, including topics such as opthalmic biomaterials, orthopedic applications, cardiovascular biomaterials, and drug delivery systems. Regulatory issues concerning biomaterials will also be addressed. Organic Chemistry and Biology. Also offered as Ceng 551.