The chemicals released by mast cells are mediators of bodily inflammatory processes. They account for the major symptoms of asthma. Among the most well-studied chemical mediators are histamines and leukotrienes. It should be recognized that leukotrienes are far more potent than histamines as stimulators of bronchial constriction and allergy. Some leukotrienes are as much as 1,000 times more potent than histamine.
Asthmatics tend to have markedly high leukotriene levels.
Also, ragweed pollen, as well as various grass and tree pollens can induce bodily production of pro-inflammatory leukotrienes. Obviously, reducing the overall allergic threshold is a key to treating asthma naturally. That is because allergens become more dangerous as exposure intensifies and increases. Thus, some of the most practical ameliorating considerations include reducing exposure to airborne and food allergens, including dust mites in the home and office, as well as other allergenic agents such as formaldehyde that may be present in furniture. However, quercetin-based therapy may also be important.