No significant side effects of chemotherapy for GTD affect future pregnancies. There does not seem to be a higher infertility rate, a lower chance for a successful term pregnancy or a higher rate of spontaneous abortion. Almost all recurrences take place within 36 months of remission, with 85 percent before 18 months. Sometimes a recurrence can appear after an intervening normal pregnancy. Recurrent disease is usually treated with chemotherapy or occasionally surgery if the metastases are isolated.
Cure rates vary, depending on the site of metastases.