Fibrinogen and prothrombin are proteins manufactured and deposited in blood by liver. When blood vessel is damaged, platelets clump at site and partially seal leak. When tissues are repaired, an enzyme called plasmin destroys fibrin clot and restores fluidity of plasma. Exchanges Between Blood and Tissue Fluid a. Two forces control fluid movement across capillary walls.
Blood pressure causes water to move from blood to tissue.
Arterial process is termed filtration because large red blood cells and plasma proteins stay in blood, water and small molecule nutrients leave. Osmotic pressure is created by presence of salts and plasma proteins in blood. Tissue fluids contain all components of plasma except large proteins. Lymph is returned to venous blood when lymph vessels join subclavian veins in shoulder region. Circulatory Disorders Cardiovascular disease is leading cause of death in Western countries.