No activity restrictions necessary. Neonatal patients may need to be transferred to the NICU for monitoring of infection, sepsis, electrolyte imbalance, and IV fluids or antibiotics. Routine follow-up as needed for symptomatic relief or to follow labs from systemic therapies. Some patients may experience an amelioration of their symptoms as they get older. Educate patients about potentially passing their chromosomal defect on to their children.
All photos are in the public domain.
Close-up of ankle. Genetic approaches to understanding the keratinopathies. Mutations in the genes for epidermal keratins in epidermolysis bullosa and epidermolytic hyperkeratosis. Prenatal diagnosis for keratin mutations to exclude transmission of epidermolytic hyperkeratosis. Keratin and keratinization.