Other side effects can be more permanent and dangerous and some treatments could even cause side effects that occur later, after the treatment is over. These late effects may include major organ damage, sterility or a second cancer. The physicians conducting the clinical trials are very concerned about these side effects and are trying hard to prevent late complications of treatments. Moreover, during the trials and afterwards, patients participating are often monitored closely for any adverse effects. It is a difficult decision for any patient, whether or not to join a clinical trial.
Cancer is potentially a life-threatening disease.
The cancer itself can cause dangerous symptoms on its own and standard treatments can also cause side effects. Another critical variable is your condition as a patient. All of these issues should be considered and weighed against the risks and benefits of new research treatments, before deciding to participate in a clinical trial. Make sure you ask about any part of the form that is not clear. You don't have to participate in the trial if you want to and even if you sign the informed consent form, you may drop out of the treatment program at any time and can receive other available medical care.