Glycolysis, while necessary for survival, is also the leading cause of free radical activity. Free radical activity is central to the aging process and brain cell death. In recent research, severe calorie restrictive diets have proven to significantly extend life span. Shift A significant trend in body energy utilization from youth to old age is the reduction of lipolysis and thermogenic metabolism, along with increased dependance on the glycolysis metabolism. At the same time the glycolysis metabolism becomes increasingly inefficient due to growing glucose intolerance and insulin resistance.
Ages lead to various aging diseases.
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