My research often requires development or modification of specialized micro-techniques for measuring pH, or ion concentrations inside or adjacent to epithelial cells, or in nanoliter samples of biological fluids. We have shown a clear functional separation between control pathways acting on cation and anion secretion in Drosophila MTs.
Analysis involves electrophysiological, pharmacological and molecular genetic techniques.
Hormonally-controlled chloride movement across Drosophila tubules is via ion channels in stellate cells. Quinlan, M.C., N.J. Tublitz and M.J. O'Donnell. M.J. O'Donnell, C.M. Pilley and P.A. Wright.