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Dear Friends, On March 5, South Africa's High Court began hearings in a closely watched case that could mean life or death for millions of people in Africa, and will affect the very future of the continent itself. As you no doubt know, the world's leading pharmaceutical companies filed suit in 1998 against then president Nelson Mandela and nine other respondents. The United Nations estimates that 3 million people died of AIDS last year, 2.4 million of them in Sub-Saharan Africa . Drugs that have revolutionized AIDS treatment in the rich countries are priced far too high for African countries to afford. Drug industry profits are soaring.