This abnormal protein comes from cells in your bone marrow. The heart, kidneys, nervous system and gastro-intestinal tract are most often affected.
Amyloidosis is a bone marrow disease.
Your bone marrow makes protective antibodies. Antibodies are proteins that protect you against infection and disease. After they have served their function, these antibodies are broken down and recycled by your body. If you have amyloidosis, cells in the bone marrow produce antibodies that cannot be broken down. These antibodies then begin to build up in the bloodstream.