It has been invariably some kind of softwood shavings. Although our data do not qualify as a truly scientific experiment, there is enough evidence to suggest using caution. Documented scientific research has already shown that aromatic softwood beddings are potent enough to alter biological functions of the liver. Apparently it s not a result of ingesting but rather inhaling the fumes, which contain phenols, or toxins which pass in the fumes from the lungs to the blood and are finally filtered through the liver. The fact that a large number of indoor house rabbits live in an environment of pine or cedar may account for the large number of deaths due to liver damage and anesthesia fatalities.
Blood panels are now inexpensive since basic lab work is done in most veterinary offices.
Alternative choices will depend on individual habit differences. We ve observed, however, that rabbits tend not to chew on material which is urine soaked. New organic hull and grass litters have been developed by several companies. We're hoping that the perfect bunny litter will be available soon. It must be non-toxic, easy upkeep, easy disposal, lightweight and inexpensive.