Johne's-infected animals will often respond to parasite control if they are infected with parasites. However, she says, it only postpones the inevitable. Most animals in Stage 3 are shedding billions of organisms and are positive on fecal culture. Many are positive on serologic tests. Stage 4 - the final stage of the disease.
Animals become emaciated with fluid diarrhea and develop bottle jaw.
Officially described as hypoproteinemia and edema under the lower jaw, bottle jaw appears as a lump under the jaw. It's also a symptom of parasite infection, so it's not specific to Johne's disease. So those that do are the tip of the iceberg. How it starts Most experts agree that infection usually occurs in the neonatal period - in utero or right after a calf is born, says Whitlock. The most common means of transfer is believed to be fecal-oral.