Fibrosis is common to several chronic liver diseases, as it is a sign of hepatic injury. A diagnosis of fibrosis is usually determined with a liver biopsy. The clinical feature that is most apparent with fibrosis is portal hypertension. Cirrhosis of the Liver Cirrhosis is a chronic disease that is characterized by a permanently injured and scarred liver. Cirrhosis is the end-stage of chronic liver damage.
Diagnosis is made from a liver biopsy.
With cirrhosis, scar tissue prevents liver function by reducing the normal flow of blood throughout the liver. When the flow of blood is blocked, liver cells cannot be reproduced normally. As the liver regenerates, the loss of normal liver tissue affects the function of the liver. A normally-functioning liver produces and processes certain necessary substances for the body. Nutrients from foods and toxins, as well as hormones and drugs, are all processed in the liver.