The cardinal manifestations of overdosage are drowsiness and confusion, reduced reflexes and coma. There are minimum effects of respiration, pulse and blood pressure unless the overdosage is extreme. There is no specific antidote known. Gastric lavage may be beneficial if performed soon after oral ingestion. If necessary, a CNS stimulant such as caffeine or methylphenidate may be administered with caution.
Dialysis appears to be of little value.
Dosage Valium Roche Injection is used without diluent for both the i.m. and i.v. routes. The i.m. route should be preferred whenever the indication and urgency of the clinical situation permit. The i.v. route is indicated when diazepam injection is used prior to cardioversion. Repeat in 3 to 4 hours, if necessary. For tetanus, larger doses may be required.