Along with mortgage payments, you're going to have other costs like home repairs, home improvements, home insurance and general home maintenance that you didn't have when you were renting. You're going to need every extra penny you have. Along with whether you can afford a house, you should consider if now is a good time to buy. House prices have skyrocketed recently and interest rates have gone up. Prices may not go down any time soon.
Different cities have different real estate trends.
So if you don't care where you live, then check out different cities and see where you can find a good market. The Midwest is always a good place to begin such a search because the cost of living is lower than on the coasts. Either way, you take a chance. If you feel you can afford it and you're ready to buy a house, then by all means, now is the time to find your new home. But if you're really lucky, the aforementioned entourage of supermodels will buy your house for you.