Based upon this data, the IFRA makes recommendation on the safe use of fragrance materials. The fragrance supplier should inform the manufacture that the formula might contain proportionally higher levels of restricted ingredients. The formula should be then used in concentrations that would ensure no restricted ingredient was used at levels higher than what was recommended in the final consumer product. Levels of restricted ingredients may be used at a higher level in non-skin contact products. In addition to these, other items are also included because of the potential of contact with the skin.
Cinnamic aldehyde is a known sensitizer.
Using these ingredients together decreases the sensitizing effect of cinnamic aldehyde. The IFRA will consider all information brought to their attention when developing guidelines.