Grassme H et. Ligand Interactions on Epithelial Cells in Host Defense to Pseudomonas aeruginosa.
Apoptosis remains a central process in maintaining cellular homeostasis.
Even during pathogen invasion, apoptosis may serve a protective role by assisting in the clearance of microbes from the body, though the mechanism by which such processes occur remain largely unknown. CD95 belongs to the TNF-R family of 'death receptors' responsible for transducing death signals during apoptosis. Furthermore, the study highlights the essential role of non-immune cells in combating pathogenic infection by challenging the widespread perception of the immune system as the 'one and only' player during antigen invasion.