Forty percent 10-year recurrence rate if survive initial insult. Hemolytic uremic syndrome. Usually in infants, children, or pregnant or postpartum women. Presents with thrombocytopenia, fever, microangiopathic hemolytic anemia, hypertension, acute renal failure with anuria. Has been found in pond water, apple cider and uncooked or undercooked hamburger.
Day care is also a risk.
A generally self-limited IgA vasculitis. May follow URI or streptococcal infection. Aspirin and corticosteroids have been used for joint pain and GI symptoms respectively. Corticosteroids do not change the course of the associated renal disease. Bleeding caused by heparin.