Our studies is determine how we shift the Th1 response of MS patients to a Th2 phenotype and to devise appropriate measures to predict a beneficial outcome. The third model of immune suppression that we have developed deals with the effect of radiation in the induction of immune suppression. We are trying to determine the mechanism by which radiation induces suppression. We have shown that radiation itself does not induce immune suppression but makes the host more susceptible to immune suppression. We have also observed that radiation can alter immune functions of cells without necessary eliminating these from the host.
Apoptosis is induced even a extremely low levels of radiation.