Not all of the following adverse reactions have been reported with dicyclomine hydrochloride. The following agents may increase certain actions or side effects of anticholinergic drugs.
Anticholinergics antagonize the effects of antiglaucoma agents.
Anticholinergic drugs in the presence of increased intraocular pressure may be hazardous when taken concurrently with agents such as corti costeroids. Anticholinergic drugs may antagonize the effects of the drugs that alter gastrointestinal motility , such as metoclopramide. Because antacids may interfere with the absorption of anticholinergic agents, simultaneous use of these drugs should be avoided. The inhibiting effects of anticholinergic drugs on gastric hydrochloric acid secretion are antagonized by agents used to treat achlorhydria and those used to test gastric secretion.