Roger Davis is interested in the mechanisms employed by cells to respond to extracellular stimulation, leading to the regulation of gene expression in the nucleus.
Cellular proliferation is a highly regulated process.
During embryonic development, rapid cell growth is required to form the tissues of the body. In contrast, cellular proliferation in adults is slow, primarily serving to replace senescent cells. Regulation of this proliferative capacity is critically important. Errors in growth control can result in a variety of diseases, including cancer. The local environment of cells acts as an important factor in controlling cellular proliferation.