Moreover, many species can learn to sing only during restricted developmental or seasonal periods. We employ behavioral, anatomical, pharmacological, and molecular analyses to determine how maturational changes within song-related brain regions influence, or are influenced by, vocal learning. Currently, we are determining if manipulations that extend the sensitive period for song learning also delay the developmental profile of NMDA receptor expression. Through these studies, we are elucidating the mechanisms underlying periods of unique environmental sensitivity, and learning how information is stored through experience-dependent modifications of the developing nervous system. Neurogenesis and sensitive periods in avian vocal learning.
Auditory feedback is necessary for the maintenance of stereotyped song in adult zebra finches.
Early isolation from conspecific song does not affect the normal developmental decline of NMDA receptor binding in an avian song nucleus. E.J. Nordeen, and K.W. Nordeen. Blockade of NMDA receptors in the anterior forebrain impairs sensory acquisition in the zebra finch. Anatomical and synaptic substrates for avian song learning. Individual variation in neuron number predicts differences in propensity for avian vocal imitation.