Advantages Requires relatively few males. Can expand a line in a short period of time. Takes advantage of postpartum estrus, thus decreasing time between litters. Disadvantage If performed in a small shoebox cage, requires frequent and careful observation to remove pregnant females. Pair Mating Stable long-term pairs of one male and female in a single cage.
Advantages Takes advantage of postpartum estrus and decreases time between litters.
Increased production of offspring per female. Can easily be performed in a standard mouse cage. Requires less careful and frequent observation of females, as females are not removed from the cage for delivery. Can be physically demanding for females to produce repeated litters without a rest period between them. Provides method for timed deliveries.