Please conduct a current literature search and check the appropriate current online database for the most recent quantitative information. Other chronic effects in humans are cardiac arrhythmia, liver damage, and kidney effects .
Animal studies show similar responses with liver toxicity at low exposure levels.
However, no definite conclusions can be made because of the limitations of the studies. Animal studies have not reported birth defects or reproductive effects from inhalation exposure to tetrachloroethylene. The EPA is in the process of revising its cancer risk assessment guidelines and is currently reassessing this pollutant. Exceedance of the RfC does not imply that an adverse health effect would necessarily occur. As the amount and frequency of exposures exceeding the RfC increase, the probability of adverse health effects also increases.