It is also not known whether hydroquinone can cause fetal harm when used topically on a pregnant woman or affect reproductive capacity. It is not known to what degree, if any, topical hydroquinone is absorbed systemically. Topical hydroquinone should be used in pregnant women only when clearly indicated. B. Nursing mothers. It is not known whether topical hydroquinone is absorbed or excreted in human milk.
Caution is advised when topical hydroquinone is used by a nursing mother.
C. Pediatric usage. Safety and effectiveness in pediatric patients below the age of 12 years have not been established. No systemic adverse reactions have been reported. There have been no systemic reactions from the use of topical hydroquinone in Glyquin . However, treatment should be limited to relatively small areas of the body at one time since some patients experience a transient skin reddening and a mild burning sensation which does not preclude treatment.