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Aphthous ulcers are painful, severe canker sores in the mouth.
In general, patients improved a day to a day and a half sooner, using amlexanox. Pain relief occurred in conjunction with healing of the ulcers. While people with AIDS do acquire especially virulent forms of aphthous ulcers, the safety and effectiveness of this drug in immunocompromised individuals has not been assessed at this time. The drug is contained in a paste that is applied four times a day directly to the ulcers, following oral hygiene after meals and before bedtime. If the ulcers have not healed in 10 days, patients are advised to visit their dentists or health care providers.