The study of cholestatic liver diseases and the pruritus associated with them, in behavioral clinical studies, in a multidisciplinary fashion. Plasma from patients with the pruritus of cholestasis induces opioid receptor-mediated scratching in monkeys. Cholestasis in the male rat is associated with naloxone-reversible antinociception. Effects of naloxone infusions in patients with the pruritus of cholestasis. A double-blind, randomized, controlled trial.
Cholestasis is associated with preproenkephalin mRNA expression in the adult rat liver.
Pilot study of low dose oral methotrexate treatment for primary biliary cirrhosis. Bergasa NV . Pruritus and fatigue in primary biliary cirrhosis. Bergasa NV , Link MJ, Keogh M, Yaroslavsky G, Rosenthal RN, McGee M. Pilot of Study of bright-light therapy reflected toward the eyes for the pruritus of cholestasis.