The germ cell lineage gives rise to the sperm and eggs during adulthood. Lamin B protein has previously been shown to localize to the nucleoplasmic side of the nuclear envelope. The top right panel shows that Lamin B protein is present on the nuclear envelopes of all of the nuclei in the embryo. The left panel shows a merge of the Germ cell-less and Lamin B staining patterns.
Coincident signal appears yellow.
The Jongens Lab is studying how the germ cell lineage is established during embryonic development. In previous work they have shown that germ cell-less gene is required for establishment of the germ cell lineage of Drosophila and are thus trying to determine how this gene functions. In addition to studying how the germ cell lineage is established, the Jongens lab is also interested in studying the subsequent differentiation and proliferation of the germ line.