In some cases, this type of reaction can lead to depression. Some individuals are more susceptible to depression because of a genetic predisposition, says Lauren B. Marangell, director of mood disorders research at Baylor College of Medicine in Houston. Like other illnesses, depression can run in families. Vulnerable individuals may find that going through a negative experience causes their stress hormones to switch into high gear. There may be a stressor that's the straw that breaks the camel's back, which can lead to full-blown depression.
Depression can wreak havoc on the immune system, leading to a variety of ailments.
Getting help immediately may prevent a minor depression from turning into a major medical crisis. Don't just ignore it and hope it will go away. Moving on Chan remembers how down he felt when he had to leave his new friends and colleagues and the exciting life on Making the Band . He also found that returning to his old routine was difficult. Before landing the spot on the show he was a special events coordinator, a job he enjoyed.