In this issue of Life Extension magazine, we discuss a recent breakthrough in aging research by Richard Weindruch and Tomas Prolla of the University of Wisconsin in Madison. Our interview with Drs. Funding for the Science study came from other sources.
Caloric restriction is the only established method of slowing aging and extending maximum lifespan.
Weindruch and Prolla have found that many changes in genetic expression in aging animals are prevented in CR mice. Their method will enable scientists to acquire full understanding of why and how CR slows aging, which will, in turn, enable them to develop therapies to slow aging in other ways. The Weindruch-Prolla method will also enable scientists to validate methods of measuring aging over relatively short periods of time. An example of how this new technology might be applied is the European drug centrophenoxine . Some scientists believe this drug may slow human aging.