Only intramuscular penicillin has been demonstrated to be effective for the prevention of rheumatic fever. Cefdinir is effective in the eradication of S. pyogenes from the oropharynx. Only intramuscular penicillin has been demonstrated to be effective for the prevention of rheumatic fever. Once-daily dosing for 10 days is as effective as BID dosing. Once-daily dosing for 10 days is as effective as BID dosing.
Creatinine clearance is difficult to measure in outpatients.
For estimates to be valid, serum creatinine levels should reflect steady-state levels of renal function. Patients on Hemodialysis Hemodialysis removes cefdinir from the body. Tap bottle to loosen powder, then add water in 2 portions. Shake well after each aliquot. The container should be kept tightly closed, and the suspension should be shaken well before each administration.