Represents the bulk of the output from the alternative and homeopathic medicine literature. Few studies have had a positive outcome. Below we will discuss the three most often cited as evidence for a specific healing response to homeopathic remedies. They showed a small but statistically significant worsening of symptoms during the first two weeks of treatment but a small but significant improvement in the two weeks after completion of the treatment that was associated with a reduction in the amount of antihistamine needed to control their symptoms. This is critical in the study of medicine.
Clinical trials are notoriously subject to unnoticed influences and effects.
All medical observations must be repeatable in a scientifically verifiable way. The assessment of the response was subjective. This is a low number of completions for a 5 week study. The chemical composition of the treatment and the placebo was not assessed. Hay fever exhibits a large placebo response and ha a waxing and waning character that makes it hard to study clinically.