Human pathogens require a variety of vitamins - usually obtained from the host organism. Those with fewer enzyme systems require more nutrients. Organism that have very simple nutritional requirements have very complex enzyme systems. Count may actually drop due to transplant shock, trauma of transfer. Organisms must adapt to new media, perhaps induce new enzymes.
Cells increase in size, incorporate various substances from medium.
Production of toxic wastes or substances that change the pH. 4. As cells die, more toxic substances are released. If endospores form, this last phase is decreased.