Since no animal or cell model exists to mimick HCV infection, it is hard to study intervention trials. However, based on the general liver disease literature, where the majority of people accept the hypothesis that oxidative stress is a significant player in liver cell injury, even in reperfusion injury, I suggest that people hedge their bets and take decent antioxidant pills. Hep C is an RNA virus, like HIV and Ebola, and its growth levels are sensitive to selenium deficiency, so an extra 200 mcg selenium per day is important. Good nutrition in general keeps the glutathione system, a major antioxidant system in the liver, replenished. I know of no studies where Creatine hurts liver.
Creatine is simply a fuel source.
I call it muscle candy. But if you use it to work your muscles harder, then I suggest you support muscle oxidative stress clean-up with all the above antioxidants. Drink lots of water with it though. I would skip the Creatine-loading phase that people sometimes do, this does give lab reports that mimic kidney failure, and would freaek out your MD if you had blood tests at that time. Having done the research on safety, I think it is probably best to take it for about 8 weeks.