This week's artwork was donated by Vansom, a pediatric cancer patient who received treatment at The Children's Hospital of Philadelphia . For a fifteen year period it has been hospitalized in Ophthalmologic Clinic from Craiova nineteen cases with retinoblastoma, seventeenth of them have been sporadic forms and two hereditary forms. It was found chromosomal changes at the two hereditary forms, consisting by a deletion of the long arm of chromosome 13. Kliniki Okulistyki AM w Bialymstoku.
Apoptosis is a genetically regulated form of cell death.
Cell death by apoptosis is essential for normal development and tissue homeostasis, and it is involved also in a variety of pathologic processes. Apoptosis is the final common pathway of photoreceptor cell death in retinal dystrophies and degeneration, retinal detachment, vitreoretinal proliferation, retinoblastoma and retinal injury. The authors present a brief literature review concerning studies on the role of apoptosis in pathogenesis on retinal diseases. Although the search strategy has been refined as best as possible, citations may appear that are not directly related to the topic, and occasionally relevant references may be omitted. The information provided through OncoLink should not be used for diagnosing or treating a health problem or a disease.