There are tall ships available for charter in the US, in the Caribbean, Mediterranean, Greece and Turkey. You can kayak in secluded wilderness coves, hike in virgin forests, fish, see bears and whales, meet with locals at native villages, explore glaciers. There are vessels available from 12 to 100 passengers, some also cruising the U.S. west coast in the spring and fall, a few continuing down to the Sea of Cortes. There are vessels you can charter to retrace the footsteps of Lewis and Clark, paddlewheelers that go on the Mississippi and its tributaries, vessels that cruise the Great Lakes. They have satellite tv as well as telephones and a fax machine.
Cabins are air-conditioned and have a private bath with shower.
Larger ships holding several hundred passengers go into both the Amazon and the Orinoco Rivers. Extensions to Machu Picchu are available. You can charter a dive boat to dive or just use it to sightsee. They usually hold 6-16 passengers, can be chartered all over the world, from the Galapagos Islands to Turks and Caicos, South Pacific or Caribbean. There are yachts that hold 20-50 passengers or larger Greek ships of several hundred that are available from April through October to cruise the Greek islands and ports in Turkey.