Just picture God's anger in verse eleven. God is pretty smart, he figured it out. In verse twelve we have the first symptom of an unsafe world. In one sentence Adam draws a very thick, dark line around all of his relationships, and there were only two. The woman that you made did this to me.
Blame is the symptom of an unsafe relationship.
If something goes wrong I point at you and say what is wrong with you. There is something wrong with you. The woman that you made, you are the problem, and you're the problem because I am the center of my universe. She had to blame somebody, and the only relationship she had left was the one of the serpent. She blamed the serpent.