He was active in many professional pharmacy associations, including the American Pharmaceutical Association, the Texas Pharmaceutical Association, and the Capitol Area Pharmaceutical Association. Dr. Sheffield was one of the founding members of the Pharmacy Generations Club, a unique organization of parents and children who both attended the College of Pharmacy. Dr. Sheffield's service activities did not end with his retirement. During this time, he was very active in Reading for the Blind. As was fitting, Dr. William J. Sheffield was buried in Austin with full military honors.
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