Both have metalaxyl as their active ingredient. Two formulations are necessary because metalaxyl is not translocated into developing root systems from hypocotyls of seedlings. Return to Outline Mammalian Toxicity of Fungicides LD 50 values for fungicides are generally low compared to other pesticides such as insecticides and herbicides . Oral and dermal LD 50 are dete rmined by testing on laboratory animals. Oral values are determined with rats.
Dermal values are determined with rabbits.
The low mammalian toxicity of fungicides results from the fact that most fungicides target biochemical pathways unique to fungi. Effectiveness, cost, safety and development of fungicide resistance are affected. Forecasting models can be used to optimize timely application. Follow recommendations for handling and disposal. Applicator licensing required for handling and application of fungicides.