More air routes into the Mosquitia region are making that remote area much more accessible. Trains are slow, rudimentary and very cheap. Services have been disrupted in the past, so check whether the trains are actually running before planning to use one. Boats are common modes of transport between the Bay Islands and along the Caribbean coast, especially in Mosquitia, where there's just one road. There are plenty of taxis in most towns but they are not metered, so negotiate a fare before you get in.
Car rental is available in main towns and the main roads offer excellent driving.
Hitching is generally easy in rural areas, where trucks often stop to pick up passengers. We encourage you to verify any critical information with the relevant authorities before you travel. This includes information on visa requirements, health and safety, customs, and transportation.