Men will develop symptoms if the female transmits the gene for the disorder. Women may be carriers of the gene. Muscle weakness also occurs in the arms, neck, and other areas, but not as severely as in the lower half of the body. Muscle contractures occur in the legs and heels, causing inability to use the muscles because of shortening of muscle fibers and fibrosis of connective tissue.
Bones develop abnormally, causing skeletal deformities of the chest and other areas.
Cardiomyopathy occurs in almost all cases. Mental retardation may accompany the disorder but it is not inevitable and does not worsen as the disorder progresses. The cause of this impairment is unknown. Becker's muscular dystrophy occurs in approximately 3 out of 100,000 people. Symptoms usually appear in men between the ages of 7 and 26.