All articles are peer-reviewed by three or more referees.
Acceptance is based upon significance and originality. Because the review is double-blind, authors' names should not appear in the text or on the figures. Editorial revisions may be made to articles accepted for publication as an aid to clarity. Manuscript Format Five copies of the manuscript, figures, and all other supporting material must be submitted to the Managing Editor. Consult the Uniform Requirements for Manuscripts Submitted to Biomedical Journals for formatting suggestions.