The disease takes its common name from the fact that most of the etiologic agents are dark-walled. Thiabendazole, 5-fluorocytosine, and amphotericin B have all been used topically. Advanced cases may required systemic treatment for long periods of time. The skin lesions show a hyperkeratous pseudoepitheliomatous hyperplasia and keratolytic microabscesses in the epidermis. Dematiaceous hyphae and sclerotic bodies are found in the stratum corneum, with essentially only sclerotic bodies found in the areas of dermal inflammation.
Brain abscesses are typically multilocular and well demarcated with thick walls.
Irregular dematiaceous hyphae are seen in these abscesses. Incubate at 30C and discard negative cultures in 4 weeks. Phialophora verrucosa Natural habitat Soil and woody plant material Search for Chromoblastomycosis PubMed References 208. Treatment of chromoblastomycosis with itraconazole, cryosurgery, and a combination of both. Int J Dermatol.