These differences persist even after dose adjustments. In patients with CHF who cannot tolerate ACE inhibitors, the combination of hydralazine plus isosorbide dinitrate yields similar reductions in mortality. Treatment with ACE inhibitors in asymptomatic patients with left ventricular dysfunction does not convey significant benefits. Combination therapy with ACE inhibitors and angiotensin II receptor blockers has been shown to improve left ventricular function more than either agent alone. Describe the clinical use of ACE inhibitors in coronary artery disease.
ACE inhibitors prevent ventricular remodeling solely by decreasing left ventricular afterload.
The benefits of ACE inhibitors on postmyocardial infarction patients is limited to patients with impaired left ventricular ejection fractions, regardless of the clinical presence of congestive heart failure. ACE inhibitors may improve survival in patients with high cardiovascular risk even without evidence of myocardial infarction or left ventricular dysfunction. Activity Evaluation Application for Category 1 Credit - GT6.00w Use of ACE Inhibitors in Patients With Vascular Disease Please fill out the following form completely to obtain 1.5 hours of Category 1 credit.