Current detector technologies of interest include multi-channel photomultiplier tubes, avalanche photodiodes and intrinsic semiconductor detectors. We are also interested in statistical reconstruction methods to optimize image quality, and in image registration, segmentation and other data analysis tools for PET imaging. Quantitative data obtained from MRI is correlated with 3-D visualizations of immunohistochemisry to develop data for modeling the static biomechanics and kinematics of binocular alignment, with clinical application to the diagnosis and surgery of strabismus.
Clinical application is to inner ear and balance disorders.
Bone tissue forms in human arteries in close association with cholesterol deposits. Previously considered a passive process, we recently demonstrated that arterial calcification involves osteoblastic differentiation of vascular cells following the same course as embryonic bone formation. The laser research lab has pioneered the development of pulse ultra-violet of excimer lasers for biomedical applications. We continue to investigate cardiovascular, ophthalmologic, orthopaedic and neurosurgical application of this technology. Biologic spectroscopy, the use of spectral data to identify and classify tissue is another major focus of our research.