Notice the well demarcated white areas that occupy most of the node's space. When the lymph nodes are examined histologically, the normal lymph node architecture is replaced by infiltrates of neutrophils and macrophages. Write a morphologic diagnosis for this lymph node lesion. Explain why these bacteria are able to survive and incite such intense inflammation despite being phagocytized by macrophages. Return to the top Case 4 .
Circles indicate a representative group of the abnormal cells.
List three differences in the gross appearances of the two lymph nodes. List three features of the abnormal cells indicated by the circles that might be used to distinguish them from normal lymphocytes.