HPV attacks the epidermal layers through direct contact. Most resolve spontaneously. Plantar warts affect females slightly more than males. This occurs through breaks in the stratum corneum of the epidermis. Such exposure frequently is associated with using public showers.
Diagnosis typically is made on clinical grounds.
Treatment options include topical keratinolytic medications, cryotherapy, and surgery. Since plantar warts are epidermal, cautious treatment should not result in scarring. Topical keratinolytic and cauterizing agents Salicylic acid, cantharidin, and dichloroacetic acid are useful. Soak affected area in warm water, dry it, pare the top layer, and apply chosen keratinolytic agent under tape occlusion. Repeat entire process qd or qod for weeks until plantar wart resolves.