Long-term effects can include brain damage, poor concentration, memory loss and social inadequacy. Physical consequences of marijuana use include damage to the lungs, chromosomes, and reproductive system. The most severe consequences of cannabis use affect brain functioning. Chronic marijuana use can result in changes in perception, motor activity, sensation, emotional response, motivation, memory and states of awareness. Depressants Drugs in this classification include Rohypnol and other barbiturates, benzodiazepines, GHB and other depressants including ethyl alcohol.
Depressants produce rapid tolerance.
Severe withdrawal, including seizures and death, can occur if depressant use is immediately stopped. Depressants also can cause sudden death by respiratory arrest or by stroke resulting from a marked increase in blood pressure. Mixing alcohol with other depressants can be lethal.