This service provides screening of novel psychoactive compounds for pharmacological and functional activity at cloned human or rodent CNS receptors, channels, and transporters. Screening of compounds is provided to qualified academic investigators at no cost. Assays using for a large number of cloned human or rodent cDNAs for CNS receptors, channels and transporters.
Cloned receptors are also available at no cost to qualified investigators.
Who is eligible Academic investigators involved in basic or clinical research relevant to mental health. Areas of interest to NIMH include the design and development of new chemical entities and small molecules as research tools, probes, targeted drug delivery systems, and PET ligands for brain imaging. Research areas of interest are described in the Division of Basic and Clinical Neuroscience Research webpage . NIMH and Case Western Reserve University will review and prioritize all requests for screening. Requests should include A brief summary of the significance of the compound to the investigator's research.