Dr. Winokur will be looking at the antidepressant response as it relates to sleep effectiveness over a 10-week period. Study participants will be asked to spend a total of five, nonconsecutive nights in the sleep laboratory to have their sleep patterns evaluated. They will also be asked to complete a questionnaire to assess daytime sleepiness and to measure performance and mental sharpness. Routine medical exams and blood tests will be given, and study participants will be compensated. If you have been diagnosed with major depressive disorder, and antidepressant drug treatment is indicated, you may be eligible to participate.
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