It differs from methods used in other labs in various ways, generally including one or more of the following considerations. Second, it utilizes neuroanatomical rather than spatial-geometrical considerations for classification of tissue. Third, its choice and definition of units of analysis are informed by detailed considerations regarding brain development, neural systems and neural connectivity. Fourth, it does not utilize computerized warping or stretching to normalize the brain to a template, but rather leaves inter-individual variability intact. Because different laboratories use different approaches, and because they may define certain regions differently from one another, challenges arise when attempting to compare data generated by different investigators.
Differences exist in a number of dimensions.
Addressing the challenge of data comparability will form the core of this research project.