These signs and symptoms usually resolves spontaneously. G 2.4 million units IM x 1. G 2.4 million units every day for 10 days. If untreated, the ulcer can persist for 30 or more days. The lymph nodes often suppurate and require drainage.
All features are less common in women who often have asymptomatic illness.
They are usually painful and tender with ragged undermined edges, sharply demarcated and with a necrotic base. 500 mg PO QID x 7 days. Spontaneous rupture of the buboe relieves the pain. Urethral and rectal strictures as well as fistulas can be seen. Primary infection can also present as a urethritis without a local skin lesion.