Chapter abstracts .
Book reviews .
PNA mimics the behaviour of DNA and binds complementary nucleic acid strands. The neutral backbone of PNA results in stronger binding and greater specificity than normally achieved. In addition, the unique chemical, physical and biological properties of PNA have been exploited to produce powerful biomolecular tools, antisense and antigene agents, molecular probes and biosensors. Important new applications have emerged that could not be performed using oligonucleotides. Concepts are explained clearly and in practical terms and each chapter contains concise background information.