After prolonged anticonvulsant therapy, effectiveness of digitalis medication may decrease. Sulfa antibiotics May prevent normal elimination of epilepsy drugs. If taken on top of Dilantin, each drug may independently produce serious side effects. Nervous system toxicity and blood ailments are possibilities. Antidepressant toxicity can occur.
Blood thinners Increased anticoagulant effect.
Diuretics Increases effect of Lithium Anticonvulsants Antidepressants can increase seizure susceptibility. May cause excitation, delirium, rapid pulse, elevated body temperature and convulsions. Severe sedation may make concentrating difficult and driving dangerous. These medications alter carbohydrate metabolism. MAO Inhibitors, Tetracycline.