DOC for conscious sedation analgesia. Easily and quickly reversed by naloxone. After initial dose, subsequent doses should not be titrated more frequently than q3h or q6h. DOC for aspirin-hypersensitive patients. Anxiolytics - Patients with painful injuries usually experience significant anxiety.
Anxiolytics allow the clinician to administer a smaller analgesic dose to achieve the same effect.
By increasing activity of GABA, a major inhibitory neurotransmitter, may depress all levels of CNS, including limbic and reticular formation. Monitor patient's BP after administering dose and adjust as necessary. By increasing activity of GABA, a major inhibitory neurotransmitter, depresses all levels of CNS, including limbic and reticular formation. Arrange close follow-up care with the orthopedic surgeon. In hospitals without access to an orthopedic surgeon, reduction should be performed by the emergency physician prior to transfer.