Both unilateral RAS and bilateral RAS can ultimately lead to chronic renal failure. FMD-RAS is due to an abnormality in the muscular lining of the renal artery. FMD responds well to angioplasty and stenting. After plasty long-term patency of the lesion is typically seen. FMD RAS occurs almost exclusively in women aged 30 to 40 and rarely affects African Americans or Asians.
Atherosclerosis is the build up of cholesterol deposits, or plaque, in the lining of the arteries.
The class of blood pressure medications that directly affect the renin angiotensin pathway can be exceedingly effective in blood pressure control. The ACER-inhibitors and the new class of angiotensin receptor blockers can have incredible effectiveness. Sometimes patients with RAS are resistant to medication for control of blood pressure. The goal is to improve the circulation of blood flow to the kidney and prevent the release of excess renin, which can help to decrease blood pressure. This helps to prevent atrophy of the kidney.