Further reducing blood pressure doesn't seem to be beneficial but it may not be harmful either. This relieves earlier concerns that pushing diastolic blood pressure too low might increase mortality.
Diabetics benefit the most from lowering blood pressure aggressively.
However non-fatal bleeding is twice as common in patients taking aspirin. The results of this study also help relieve some earlier concern that using calcium blockers might increase the risk of heart attack. The experts now recommend using diuretics for initial treatment of hypertension in the elderly. Normally either diuretics or beta-blocks are recommended for initial therapy but diuretics are preferred for the elderly because they are more effective and better tolerated. Beta-blockers can cause more side effects especially fatigue.