Transbronchial biopsy or mediastinal biopsy generally diagnostic. May biopsy skin lesions, peripheral adenopathy, if present. However, this is nonspecific, and ACE levels may be elevated in miliary TB, silicosis, asbestosis, and other conditions. However, once diagnosis is made, can follow ACE levels as measure of disease activity though this is generally not needed. Treatment of sarcoidosis.
Corticosteroids are the mainstay of treatment.
Methotrexate and chlorambucil have also been used. All rights reserved.