Coccidioidomycosis, Valley fever, Desert fever. Humans, domestic animals, wild desert rodents and other animals. Sensitive to Amphotericin B, ketoconazole.
Arthrospores survive for months to years in soil, dust.
Amphotericin B or Fluconazole for severe or disseminated forms. Accidental percutaneous inoculation of the spherule form may result in local granuloma formation. Biosafety level 3 practices, containment equipment and facilities are recommended for all activities with cultures of C. immitis and for processing soil or other materials known or likely to contain infectious arthspores. Appropriate practices and precautions to minimize the production of infectious aerosols. In sealed containers that are appropriately labeled.