Inflammation and fibrosis cause the destruction of functioning glandular tissue in the pancreas. This results in an inability to properly digest fat caused by a lack of pancreatic enzymes. The production of insulin is also affected. Attacks may become more frequent as the condition progresses. The incidence is 2 out of 10,000 people.
Alcoholism is a risk factor.
Chronic pancreatitis occurs more frequently in men. Determining the cause of acute pancreatitis and treatment may help to prevent chronic pancreatitis. An exploratory laparotomy may be performed to confirm diagnosis. In advanced cases, all or part of the pancreas may be removed. The outcome is usually better if abstinence from alcohol is maintained.