Bitemporal constriction and hypoplastic supraorbital ridges. Downslanting palpebral fissures, blepharoptosis, and hypertelorism, Esotropia or nystagmus occur in about half the patients. Mild neck webbing may occur.
Cutaneous hemangiomas are common.
Pulmonic stenosis and atrial septal defect are the most common cardiac anomalies. Transmitted as an autosomal dominant trait.