Bicarbonate leaves for the blood side as bicarbonate, while proton either goes into the filtrate or into the blood. Chemical buffers bind protons. Organisms immediately increase ventilation to blow off carbon dioxide. Organisms begin to increase secretion and excretion of protons via the urine thereby decreasing plasma protons. Organisms reabsorb all filtered bicarbonate from the kidney tubules and add new bicarbonate to the plasma thereby increasing plasma bicarbonate.
Chemical buffers release protons.
Organisms immediately decrease ventilation to retain carbon dioxide. Organisms begin to decrease secretion and excretion of protons via the urine thereby increasing plasma protons. Organisms have incomplete reabsorption of filtered bicarbonate and increased excretion of bicarbonate thereby decreasing plasma bicarbonate. Respiratory alkalosis or acidosis means that the cause of the acid-base imbalance is a problem with the lungs. Metabolic alkalosis or acidosis means that the cause of the acid-base imbalance is a problem with the kidneys.