Efficacy Results and Associations with Chromosome 1p and 19q Loss. B.E. Shevlin, Julie E. Hammack, Thomas J. Borell, Judith R. O'Fallon, Bernd W. Scheithauer, Robert B. Jenkins. Cycles were repeated every 8 weeks, toxicity permitting, for 6 cycles. Neuroradiologist review of MRI scans has confirmed responses. Toxicity during chemotherapy consisted primarily of mild to moderate nausea, vomiting, anorexia, lethargy, sensory neuropathy, and myelosuppression.
All eligible patients remain alive.