No evidence is cited. A streptococcal throat infection. Reconsidering sore throats. In a setting with adherent patients, children with sore throats should generally get throat cultures in lieu of rapid streptococcus antigen tests. In modern Western society the incidence of acute rheumatic fever may not be high enough to justify the routine use of antibiotics for sore throat.
Antibiotics shorten the duration of symptoms, but by a mean of only about half of one day.
This study also demonstrates that QD penicillin is less efficacious than TID or QID dosing. Simplified regimens of amoxicillin of shorter duration or of less frequent dosing should be further investigated. Cost is equivalent and sore throat may resolve quicker on amoxicillin. A French Multicentre, Open-label, Randomized Study. It is also much more expensive.