Pregnancy Pregnancy Category C. Animal reproduction studies have not been conducted with topical hydroquinone. It is also not known whether hydroquinone can cause fetal harm when used topically on a pregnant woman or affect reproductive capacity. It is not known to what degree, if any, topical hydroquinone is absorbed systemically. Topical hydroquinone should be used in pregnant women only when clearly indicated. It is not known whether topical hydroquinone is absorbed or excreted in human milk.
Caution is advised when topical hydroquinone is used by a nursing mother.
Pediatric Usage Safety and effectiveness in children below the age of 12 years have not been established.