Again, characterizing the symptomology is beneficial in the aid of diagnoses. Often, language problems surface early in the disease. Bizarre psychiatric symptoms are also prevalent as a distinguishing feature. Obsessive behavior, ritualistic activities, severe personality disturbances and uninhibited actions are examples of these. CJD is a transmissible spongiform encephalopathy.
Death is usually inevitable within one year of symptom onset.
This disease is thought to be sporadic, inherited or transmitted through exposure. They are theorized to transform normal protein molecules into infectious ones by altering their shape. Transmission of CJD has been documented from corneal transplant, implantation of ECG electrodes, neurosurgical procedures and pituitary hormone administration. Additionally, the sterilization procedures used in hospitals are ineffective in decreasing the infectious nature of this pathogen. Clinical presentation is reflective of an insidious onset with a rapid progression of declining cognition.