However, it is very difficult to correlate cancer with exposure to any specific agent. Generally, the larger the dose, or exposure, the greater the response will be. Material Safety Data Sheets often contain LD50 data. Threshold Limit Values are the airborne concentrations of a material that yields no adverse health effect when inhaled forty hours a week over a working lifetime. Eye or mucous membrane irritations can also occur.
Chronic exposure can result in dermatitis and system effects.
Corrosives usually produce acute effects, including eye, mucous membrane, and upper airway irritations. Dermatitis and severe burns can occur with skin contact, and bronchitis can develop with chronic exposure. Poisons can cause systemic disease, or fatality. Consult the MSDS for other classes of chemicals. Most methods of detection rely on the observations of laboratory workers.