This results in an inability of the body cells to use sugars and carbohydrates. Inflammation of bone marrow as a result of infection. A benign tumour growing from the fibrous coverings of a peripheral nerve. This condition generally has no symptoms but if developed on a nerve root sheath is painful and can compress the spinal cord. There is a link between peripheral vascular disease and diabetes as a result of the effects of diabetes on the circulatory system.
Atherosclerosis has a higher incidence in people who have diabetes.
The excess glucose in blood can cause atherosclerosis and arterial thickening. When sugars cannot be used, fats in the body are mobilised, increasing blood cholesterol levels to potentially form fatty deposits within the microcirculation. The most common cause of upper extremity amputation is trauma. The most common cause of lower extremity amputation is peripheral vascular disease, especially diabetes. Since UE amputations are commonly caused by trauma, they are more likely to occur in healthy young people who engage in risky activities more frequently than older adults.