Activity is increased when used with didanosine, lamivudine, stavudine, zalcitabine, or zidovudine.
Treat HIV infection when antiretroviral therapy is required. Safety and efficacy have not been determined in children less than 2 years of age. Side effects were determined when used in combination with other antiviral drugs. Anxiety, depression, dizziness, emotional lability, hyperkinesia, insomnia, migraine, paresthesia, seizures sleep disorder, somnolence, suicide ideation. Anemia, leukopenia, thrombocytopenia.