Most cases of gestational DI can be treated with desmopressin. In rare cases, however, an abnormality in the thirst mechanism causes gestational DI, and desmopressin should not be used. A specialist should determine which form of DI is present before starting any treatment. But testing should make the diagnosis clear. Your physician must determine which type of DI is involved before proper treatment can begin.
Diagnosis is based on a series of tests, including urinalysis and a fluid deprivation test.
Urinalysis is the physical and chemical examination of urine. The urine of a person with DI will be less concentrated. Therefore, the salt and waste concentrations are low, and the amount of water excreted is high. A physician evaluates the concentration of urine by testing its specific gravity or osmolality. This test measures changes in body weight, urine output, and urine composition when fluids are withheld.