Glossary Term Definition ADME Absorption, Distribution, Metabolism and Excretion. The body handles drugs by these essential processes.
ADME studies are a key part of the regulatory process for western drugs.
Refers to experiments conducted in living animals or people. The degree of agreement between in vitro and in vivo experiments. Since the goal of in vitro experiments is to predict the outcome of an in vivo experiment, the higher the correlation, the better the in vitro method. The process by which the body chemically alters the structures of substances in order to inactivate them and to make them easier to eliminate from the body. The rate processes relating to the absorption, distribution and elimination of drugs from the body.