Granulocyte concentrates should not be irradiated. Granulocyte transfusions may be useful in neonatal sepsis. Granulocyte concentrates should be administered within 24 hours of collection. Haemophilia A. Haemophilia B. Thrombophilia. Maintenance of blood volume.
Acid base disturbances.
FFP transfusions are primarily indicated to replace single or multiple deficiencies of clotting factors for which specific component therapy is unavailable or desirable. FFP is a source of anti-thrombin III for patients who are deficient in this inhibitor and who are undergoing surgery or requiring heparin for thombosis. FFP must be given on a group specific basis only. Some patients may be exchanged with cryopoor plasma. Platelets have HLA, platelet specific antigens, and ABO antigens expressed on the membranes.