SkeleTech researchers use animal models to evaluate the safety and efficacy of therapies before they can be tested on humans. Among the animal models offered by SkeleTech are osteoporosis in mice, rats, and primates. Osteoporosis, a disease characterized by low bone mass and deterioration of bone tissue, leads to increased bone fragility and risk of fracture. Other risk factors include certain genetic disorders, smoking, low calcium in diet, heavy alcohol consumption and use of certain medications, such as steroids. Animal models have been instrumental for understanding the underlying causes of osteoporosis and for developing therapies for this and other crippling bone diseases.
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