Focally, mild erythema also develops. The patient may experience stinging or burning, while a zone of pallor develops around the erythematous area. The pallor eventually extends into the region of erythema and this area develops into a blister. No known predilection exists for any particular race. No known predilection exists for either sex.
Children often present with poorly fitting shoes and complaining of a blister on the heel.
In regions of the body where the stratum corneum is thinner, a repeated friction force will cause the stratum corneum to erode and, instead of a blister, an erosion or abrasion will occur. Moisture and lubricating substances present on the skin surface are additional factors. With a greater frictional force, fewer cycles of rubbing against the skin are needed to produce a blister. Moisture on the skin surface may either increase the friction force or, in the case of very moist skin, decrease it temporarily by providing lubrication. Heat, sweating, and maceration of the skin may predispose to friction blister formation.