Cell death followed by regeneration has a promoter-like effect. The mechanism, however, has nothing to do with normal use. The cells with one mutation is at least partly inclined towards growth, so it will be more receptive to effects of a promoter than would a normal cell. The increased growth that is caused by a promoter is reversible if you stop giving the promoter. It might press on a nerve or cut off blood supply or block some tube, for instance.
Cell growth increases the population of cells with one or two mutations.
If you have 1000 such cells, your chances that one of them will mutate is 1000x greater than if you only have one such cell. Additional carcinogenic traits often appear during progression Agressiveness, metastasis, and other undesirable traits may also be linked to oncogene activity. Other related genes are for extracellular matrix proteins and similar factors which would affect migration of cells. Clinical implications of molecular events Carcinogenesis is a complicated process, and there are many places along the pathway for intervention. Exposure, development of carcinogenesis.