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IRB Continuing Review this from will be generated by the IRB office and sent to investigator for completion on at least an annual basis, depending upon the degree of risk. IBC Packet includes instructions and forms for new protocol submissions involving rDNA IBC Amendment should be completed and sent to the IBC for all proposed changes to an existing research study involving rDNA IBC Continuing Review this form will be generated by the IBC office and sent to the principal investigator for completion on at least an annual basis, depending upon the degree of risk.