Click here to view. Endometrial Polyps Endometrial polyps are benign tumors consisting of surface endometrium, fibrous stroma, and thick-walled, centrally positioned blood vessels. The endometrial cells do not have the chromosome 6 rearrangement. 6p21 resulting in an abnormal signal to grow. Polyps peak between ages 40 and 50 years, but many cases occur in menopausal women.
Curettage often fails to remove endometrial polyps because of the mobility of their body and tip.
In menopausal women taking hormone replacement therapy who have abnormal uterine bleeding, polyps are commonly found by hysteroscopy. Multiple case reports indicate that tamoxifen treatment may stimulate the development and growth of endometrial polyps. Other Benign Uterine Disorders Adenofibromas are benign tumors of epithelium and stroma that contain fewer that 4 mitoses per 10 high-power fields. Women with adenofibromas usually are elderly. In women who desire future childbearing, every effort should be made to preserve ovarian tissue unless a cancer diagnosis necessitates the removal of both ovaries.