Depression is a serious problem with a biochemical basis.
It results from an upset in the delicate balance of brain chemicals that regulate mood. It's a powerful disease that can leave us debilitated, unable to work, maintain relationships, or deal with other responsibilities. One in five women will suffer from major depression at some time in her life, as will 1 in 15 men. Millions of depression cases are never diagnosed or treated. Untreated, major depression may last for 6 months to a year, becoming more frequent and severe.