Because of this result, and because blebs were typically already present immediately following dissection, we reasoned that the state of the cochlea during dissection was important in determining whether hair cells could recover from blebbing. Since only a single bathing medium can be used during dissection, we examined whether changing that bathing medium had an effect on blebbing. We discovered several changes to the dissection medium that affected blebbing. Subsequently perfusing AP led to bleb growth. Note that no blebs are visible in this image.
Blebs are visible to the right of each hair bundle.
However, blocking transduction channels with gentamicin had no effect on blebbing. These results suggest that the transduction channel is not the primary site for ion entry in blebbing.