These medications seem to have a significantly reduced likelihood of development of neurological side effects as well. This recommendation should be discussed carefully between the patient and his or her physician. A final issue in the use of the psychotropic medications is the issue of discontinuation. The timing of discontinuation of psychotropic medications is an important and highly individual decision, which should always be made in conjunction with one's physician. As a general rule, stopping medications in a gradual way is preferable to abrupt discontinuation.
Discontinuation syndrome has a variable presentation.
Patients often will feel as if they have a severe case of the flu. Abrupt discontinuation of lithium in the context of manic depressive illness carries the risk of a sudden return of manic or depressive symptomatology. In addition, there is a small group of manic depressive patients who, once they discontinue lithium, become refractory to its effectiveness at a later time. These medications can be highly effective and may significantly alter the course of an individual's life. One must always keep in mind that the choice to take the medication is based on an assessment of the risks and benefits associated with taking medication as well as not taking the medication.