It is not a disease of humans. The hallmark sign of FMD infection is the production of blisters or vessicles. These are typically found in the mouth, on the tongue, on the nose or snout, on the teats and on the feet .
Animals drool, run fevers, lose their apetites, stop producing milk and become very lame.
As the blisters progress and rupture they may result in the complete sloughing of hooves or the covering of the tongue. It can kill young animals. The incubation period, the time between infection and clinical signs of disease, is 2-14 days. The animal can begin shedding virus before it shows clinical signs. FMD occurs routinely in parts of South America, Asia, eastern Europe and Africa .