There are peripheral regions however, showing necrosis and contour irregularities. The viable central region is light tan and fairly homogenous. Rare, however leiomyosarcomas are the most common sarcomas that involve the prostate gland in the adult. Most patients are between 40 and 70 years old. Median size of reported cases is 5 cm.
Cut surface is tan and fleshy.
The tumor is a spindle cell neoplasm. The greater the nuclear pleomorphism and the greater the number of mitotic figures, the more certain one is of malignancy. Because smooth muscle tumors are rare in the prostate, criteria distinquishing leiomyosarcoma from leiomyoma have not been established. Prostate Biopsy Interpretation. Raven Press, 1989.