Low doses typically produce euphoria and decreased inhibition as does alcohol, Mid-range doses cause body wide anesthesia and enhanced sensations and impaired perceptions which can result in panic and violent defensive behaviors. Significant injuries may not be felt as pain. Large doses produce paranoia, auditory hallucinations, psychosis, seizures, muscle rigidity, acute renal failure, and death. It is the only hallucinogen that animals will self administer. It reduces reuptake of dopamine and thus acts very much like schizophrenia.
Abusers tend to be violent and uncontrollable - really out of their minds.
Overdose can be fatal. It is secreted into the stomach and can be removed by suction. Adverse effects include confusion, depression, sleep problems, anziety, and paranoia. Physical adverse reactions include muscle tension, teeth clenching, nausea, blurred vision, faintness, chill or sweating. There is also a risk of increased heart rate, high blood pressure and perhaps brain damage in the areas of thought, memory, and pleasure.