Krabbe disease, like many other storage diseases, has an early onset form and a late onset form. In the early form, symptoms begin in the first months of life with feeding problems and failure to thrive , unexplained fevers, and vomiting . Changes in muscle tone are frequent, and seizures may begin very early and are severe. Visual and hearing losses are progressive. Affected children eventually assume a rigid unusual body position called decerebrate posturing.
Death follows shortly thereafter, usually before the second year of life.
The late onset form of the disease begins in late childhood or early adolescence . Visual problems progressing to blindness may be the first symptom. The information provided herein should not be used for diagnosis or treatment of any medical condition. A licensed physician should be consulted for diagnosis and treatment of any and all medical conditions. Inc. Any duplication or distribution of the information contained herein is strictly prohibited.