Both basal and stimulated gastric acid secretion are inhibited, regardless of the stimulus. May have antimicrobial activity against Helicobacter pylori.
Absorption begins only after lansoprazole granules leave the stomach, but absorption is rapid.
Food does not appear to affect the rate of absorption, if given before meals. Maintain healing of duodenal ulcer. Maintain healing of erosive esophagitis. Reduce dosage in impaired hepatic function. Symptomatic relief does not preclude the presence of gastric malignancy.