This is a well-done systematic review which demonstrated that naproxen, ibuprofen and mefenamic acid are effective. Aspirin was less effective and paracetamol 650 mg was not effective in a single study. The authors conclude that, based on efficacy and absence of common adverse effects, ibuprofen is probably the treatment of choice. The only complaint one could have is the issue of dose. It would be helpful to know the NNTs at particular dose levels, though we suspect that the authors reflect what they found in the original reports.
Bandolier wishes to thank the authors for making original data available.
WY Zhang, A Li Wan Po.