A mitochondrial import factor purified from rat liver cytosol is an ATP-dependent conformational modulator for precursor proteins. Effects of thyroid status on the expression of metabolic enzymes during chronic stimulation. Analysis of the functional domain of the rat liver mitochondrial import receptor Tom20. Medline J. Biol. 1990 Requirement for Hsp70 in the mitochondrial matrix for the translocation and folding of precursor proteins.
Cytoplasmic chaperones determine the targeting pathway of precursor proteins to mitochondria.
Active unfolding of precursor proteins during mitochondrial protein import. The role of thyroid hormone and promoter diversity in the regulation of nuclear encoded mitochondrial proteins. Evaluation of oxidative phosphorylation in hearts from euthyroid, hypothyroid, and hyperthyroid rats. Enhanced cytochrome oxidase activity and modification of lipids in heart mitochondria from hyperthyroid rats. Prechaperonin 60 and preornithine trancarbamylase share components of the import apparatus but have distinct maturation pathways in rat liver mitochondria.