Bromoform can cause irritation of the eyes and nose.
Tribromomethane is released to the environment by industrial activities involving bromine and is formed during the chlorination of water, perhaps by the haloform reaction. Anaerobic biodegradation may occur, but aerobic biodegradation is not expected to be significant. Hydrolysis is expected to be slow. Release of tribromomethane to the atmosphere will result in the reaction of tribromomethane with photochemically generated hydroxyl radicals with an estimated half-life of 1.45 yrs. Direct photolysis in the troposphere is not expected to be significant, but may occur in the stratosphere.