The conditioning influence of space and time is such that nothing can be known except as being present in space and time. Even if one closes the eyes and imagines the existence of an object, it would be a presence conceived in space and in time. Even if one tries to abolish the notion of space and time in imagination, one would be doing this act of abolishing the concept of space and time by being in space and time only. One cannot go out of this circle. It means that the mind is involved in the notion of space and time.
All objects are spatio-temporal, including one s own self as an observed subject.
Inasmuch as the mind is conditioned in this manner, one cannot hope to have an unconditioned knowledge of anything. The instruments of perception are restricted by the operation of space and time. One s own reason itself is a limited faculty. There are certain mathematical and set ways of thinking which go by the name of logical affirmations. Logic is an instrument that the mind has manufactured out of the mathematical compulsion inflicted upon it by the operation of space and time.