Learn your instrument. You need to be familiar enough with your instrument that you don't have to think to play it . Learn the techniques you need in order to play the sounds you want. Learn the sounds , where they are and how to get them. Emphasize tone and emotion more than speed.
Blues is about tone .
It's about feelings and soul. Remember, there are no unimportant notes . Make sure each note is played clearly, cleanly, in time, with good tone, and given its proper due. Leave some space . The rest is a valid musical expression.