History - The owners complaints about an animal with a coagulation disorder are varied. Generalized weakness may be due to hypoxia either from anemia or hypovolemia or both. The owners may notice bruising, hematuria or blood in the feces. Bleeding into joints can cause lameness or joint swelling. Ask questions about drug or chemical exposure.
Coagulation disorders are more likely to result in bleeding from multiple sites.
Single site bleeding may be due to local disease at the site and not due to a coagulation disorder. If splenomegaly or hepatomegaly are present, immune mediated diseases should be considered. A rectal examination should be performed to evaluate for bleeding into the gastrointestinal tract. Be able to interpret abnormalities in all of the following tests. Inherited diseases of hemostasis Vascular disease such as Ehlers-Danlos syndrome are rare.