The Revised European-American Lymphoma classification contains more than two dozen categories. The contrast between the two types of lymphoma is remarkable. In that study, the median time to treatment was three to four years, and more than two thirds of patients required treatment not for symptoms but because of bulky lymphadenopathy. The median survival in follicular lymphoma is nine years. Large-cell lymphomas are potentially curable, but if remission is not achieved, most patients die within 12 months.
Age is a particularly important factor.
Rates of complete remission in patients older than 60 are similar to, or only slightly lower than, those in younger patients but older patients are more likely to experience relapse. The patient received six cycles of chemotherapy with cyclophosphamide, doxorubicin, vincristine, and prednisone over a four-month period. Complete remission was achieved. The patient's follow-up was scheduled for every three months for the next two years, every six months for the subsequent three years, and annually thereafter. Chemotherapy with cyclophosphamide, doxorubicin, vincristine, and prednisone is the treatment of choice for large-cell lymphoma.