Other platelet-inhibiting agents such as ticlopidine or dipyridamole have no effect. Avoid excessive warming or dependency of the extremity. Avoid vigorous exercise. Spontaneous remissions may occur. Early-onset disease is less responsive to treatment and is generally unremitting.
Complications appear to be more frequent in patients who clearly have platelet-mediated disease.
Elevate legs when possible. Modify environment so that it is not too hot. A clue to the early diagnosis of myeloproliferative disorders. Classification and diagnosis of erythromelalgia and erythermalgia. Medicine is a constantly changing science and not all therapies are clearly established.