Powell, a senior from Dayton, Ohio, was charged Monday with felonious assault, carrying a concealed weapon and using a firearm during the commission of a felony.
Convictions carry two to five years in prison.
Powell drove off, but was later arrested by a sheriff's deputy. Powell and the other motorist reportedly exchanged words weeks ago, according to Kalamazoo police. The shooting happened after the two met up again Friday, police said. Both of Powell's parents died within the past six months, the Kalamazoo Gazette reported. Powell twice was suspended in his final season, missing three games for violating unspecified team rules, the newspaper reported.