Dr. Derek Lovley Dr. Lovley's research is focused on the physiology and ecology of novel anaerobic microorganisms. These studies are being approached at the genetic, biochemical, and ecological level. Dr. Thomas Lessie Dr. Lessie's research is directed towards understanding the genetic and enzymatic mechanisms underlying the extraordinary degradative potential of the bacterium Pseudomonas cepacia. This microorganism has attracted attention as a possible agent of bioremediation because of its ability to utilize toxic compounds as sources of carbon and energy for growth. An unusual feature of this bacterium is that it contains multiple chromosomes.
Current research is focused on the functions and origins of the different chromosomes.
Mobile gene-activating elements appear to play an important role in the adaptation of P. cepacia to degrade novel compounds. One aim of the research is to explore whether adverse physiological conditions can accelerate the pathway evolution by triggering genetic rearrangements involving such elements. P. cepacia may represent an important model system for understanding how bacterial populations respond to environmental stress. The primary objective of Dr. Leschine's research is to advance understanding of fundamental aspects of the biology of polysaccharide-fermenting microorganisms. Anaerobic microorganisms that ferment these polymers play a central role in carbon cycling on the planet as a source of CO2 and, indirectly of CH4.