Atopic dermatitis spontaneously resolves by puberty in most patients, but it sometimes recurs at times of stress or for unknown reasons. In adults it may appear as recalcitrant hand eczema or as a localized or generalized dermatitis. Acute lesions of atopic eczema are itchy, red, edematous papules and small vesicles that may progress to weeping and crusting lesions. Chronic rubbing and scratching often cause lichenification and hyperpigmentation. The classic dermatitis, eczema, rash triad of atopy consists of asthma, allergic rhinitis, and atopic dermatitis .
Atopic dermatitis is associated with a personal or family history of atopy.
Atopic skin is particularly susceptible to bacterial and viral infections, which may become widespread. These patients may develop widespread herpes infections of the skin. Triggering Factors Wool or synthetic clothing, extremes of temperature, low humidity, and sweating may exacerbate symptoms.