By judging them, they will feel persecuted and you will drive them away and push them towards alienating themselves more. What you want to achieve is an opoen line of communication between the both of you, not distancing yourself away from each other. Be supportive and reinforce it. Let your loved one know that you will always be there for them, through thick and thin. And then prove it.
Action speaks louder than words.
Go out of your way to support them in their work, career, and personal ambitions. Let them know that no matter what, you will always be there for them - physically and emotionally. If your spouse is prone to depression for example, watch for the symptoms regularly. The moment you see he or she may be going into depression or a depressive mood, call the doctor for an appoinment before the problem gets worse. They say prevention is better than cure.