Images are integrated as a function of the programming. Story never takes precedent in the CD ROM game market, game play does. Resizing is sometime done, but usually not necessary. It's most often a function of the art department. Same answer as above.
Compression is always an issue.
Since sound and picture are streamed using different channels, synch is a problem. The fact that delivery systems, ie the computers people use to play the game, are different and a game is sensitive to the different machines. Also, how many applications are running while the game is being played will effect the gameplay and synch. Being an interactive media producer is quite different from producing films. Producing film requires management of more people and more assets.