Aa , Hyperpolarizing current pulse injected through the dendritie recording electrode and the passive response recorded at the soma. Ba , hyperpolarization applied at soma is electrotonically conducted to the dendritic recording site. Ab , Depolarization of the apical dendrite elicits a local burst response consisting of fast and slow components. The response of the soma is a burst of fast action potentials. Bb , Depolarization of the soma produces repetitive firing.
Attenuated spikes appear at the dendritic location.
Cellular basis of neuronal synchrony in epilepsy. Science 241, 339-341. Synchronized oscillations in hippocampal CA3 neurons induced by metabotropic glutamate receptor activation. Secondary activation of a cation conductance is responsible for NMDA toxicity in acutely isolated hippocampal neurons. Reviewer for scientific journals.