Psychological and emotional rejection accounts for others and genetic errors also takes its toll. Anyone can be damaged. Let us be grateful when we are not. Some people see the damaged and get very negative. I don't know all the answers to such rhetorical questions, but I do know that such questions are often used as an excuse to do nothing.
Deformities can be terrible, but some types of criminal behavior are even worse.
The greatest comfort and the greatest power in this world is faith. Happy is the person who realizes how temporary is the body and how permanent is the spirit and they choose not to be damaged by living without faith. Whenever we are involved in any of the above activities even a little bit, we shall receive our reward.