The Clinical Linearity Algorithm Clinical Linearity is a revolutionary concept in the clinical laboratory arena. A new mathematical approach specifically determines whether a data set is linear within a user-defined allowable error. You no longer need to visually judge whether a method is linear.
Allowable error is expressed in units of concentration or percent of concentration.
Use the allowable error to calculate error bars for each linearity point. Attempt to draw a straight line through the error bars. If a straight line can be drawn, then the data are linear within the allowable error. Identify and eliminate outliers, continuing until the remaining points are within allowable error or until only three points remain. Calculate Intrinsic Error before and after excluding outliers.