Acarbose inhibits a glucosidases in the brush border of the small intestine, inhibiting glucose absorption. The worst case scenario would be a young diabetic with necrotising fasciitis. The problem lies in that, in many cases, the metabolic upset cannot be resolved without surgical intervention, and the perioperative course carries a high risk. Abdominal pain may be present. Subsequent progression to altered consciousness or frank coma may occur.
Body temperature is normal fever suggests the presence of infection.
Leukocytosis is a feature of diabetic acidosis per se and may not indicate infection. Similarly, initial serum phosphorus levels may be high despite depletion of body stores. Magnesium deficiency also may be present. Hypertriglyceridemia Prerenal failure, reflecting volume depletion, is usually modest in degree and reverses with treatment. The serum amylase level may be elevated, and frank pancreatitis can occur.