If you have a current HPUX account, your NT account has already been created. If you do not have an HPUX account see Mark Wilson first.
All users have a personal profile.
This should be more than enough space to hold all of your settings and preferences. You just have too much stuff. To resolve these problems you can move the files to another location. If you are logged on to a Windows NT machine, you should have a Network Drive mapped that points to your HPUX Home location. This is where you should store your files.