It was suggested that CDC be approached through its interest in food safety. Presentation of Dr. Strober . This disease is mediated by TH2 cells. In the immune system, humoral immunity, cell-mediated immunity, prostaglandins, cytokines, and neuropeptides have been cited as playing roles. Serum antibodies to p ANCA are markers for ulcerative colitis.
Cytokines are a major area of investigation.
We should also look at the role of Cox2, an oxygen metabolite. Dr. Fiocchi also mentioned adhesion molecules. In the non-immune system, epithelial cells and mesenchymal cells may play a role. In IBD, cells are both effectors and targets. Acute and chronic IBD seem to be two different diseases.