Generally, small colleges and universities offer smaller classes where you can get to know your faculty and fellow students more easily. Large universities usually have large lectures, especially in introductory courses, but have better-known faculty, a larger selection of majors, and a more competitive athletic program. Cost - Unless you're the latest winner of Survivor, money is an important element to you and your parents. If you haven't had a part-time job in high school, it may be hard to adjust to working while taking college courses. If you really need to save money, consider going to a community college for a couple years.
Community colleges are very affordable.
Majors - If you already know what you want to be when you grow up, that's terrific. Most high-school students, however, have no clue. In fact, most college students are indecisive about picking a major because they don't know what they want to do with the rest of their lives. My advice - don't worry. College is a fascinating, mind-opening experience.