Alcohol is the most common cause.
Toxic, metabolic and hypoxic conditions of all types. Liver is the principle organ of fat metabolism and synthesis. Interference with mobilizing triglycerides out of the liver is the usual mechanism. This happens when toxins or agents affect the mitochondrial and microsomal functions resulting in defective oxidation of fatty acids and aberrant mitochondrial function. Factors casuing fatty change do not all act in the same way.