While the KN system should be designed to allow scientist to use their own data, it should be made accessible to all. A critical realization is that the stakeholders are key to the success of a KN system. Success of a KN requires active participation by the community for which the KN is being created. The process will create new ideas that change the approach to data handling. This implies a world view for a domain, but science is about breaking world views.
Classification schemes hide the world view.
A possible way around this dilema is the use of extensible schema that evolve with the discipline. Alternatively, scientists need to interact with an abstraction of data, rather than the real data set. As with any abstraction, human modeling is needed to test the appropriateness of the representation. An even bolder approach is to create metadata for all of science, a meta-thesauri. The difficulty with this is that systems are developed within a culture.