Tolerance to the drug is achieved quickly. Heroin withdrawal symptoms include vomiting, nausea, cramping and severe shaking and can last up to 72 hours after discontinuation of use. Because the user is never sure about the potency of the drug, overdose and coma or death can result. Solvents that are often inhaled include glues, gasoline, paint thinner, hair spray, spray deoderants, spray paint, liquid paper, and rubber cement, all of which are often within reach of children. Long term use can cause weight loss, fatigue, and permanent damage to the central nervous system.
Brain damage can also occur.
Extremely high doses can cause a rapid or irregular heartbeat. Anxiousness and moodiness are also side effects of stimulant use. Amphetamines can cause a sudden increase in blood pressure that can result in stroke, or heart failure. Long-term use of amphetamines can cause a form of psychosis that includes hallucinations, delusions, and paranoia. While cigarettes remain perhaps the most popular form of nicotine-intake, snuff and chewing tobacco are also common.