The passive immunity acquired by the pup is only temporary until the time when the pup's immune system begins to mature, so it can produce antibodies on its own. The maternal antibodies will interfere with successful vaccination if the dog is vaccinated when the antibody levels are still quite high. Therefore you must wait to vaccinate the puppy until five to seven weeks of age. Recommended vaccine schedule involves at least two vaccinations, starting at 6 weeks old, 2-4 weeks apart until the dog is 12 weeks of age. 19 Vaccinations are usually performed in combination with canine distemper virus vaccine protocols.
Annual vaccination is recommended.
For puppies that do not receive colostrum, immunization can start at 2-3 weeks of age, and repeat every 3 weeks until 12 weeks old. 10 Protection from and reduction of environmental contamination To decrease transmission from infected animals, soiled environment and contaminated objects must be disinfected. The virus may survive for days to months in the environment. CAV-1 also survives disinfection with various chemicals, such as chloroform, ether, acid, and formalin, and is stable when exposed to ultraviolet radiation. 6,10 chemical disinfection is possible with iodine or bleach.