If you already have a higher level of water in the intracellular space because of the creatine, you end up with even more of an imbalance. Over time it may make you dehydrate faster, which is associated with heat illness and cramping. More importantly, however, overuse of the supplement can lead to kidney problems. After awhile, you retain water and your urine becomes highly concentrated. To avoid this problem, increase your fluid intake so that you'll have more of it to go through your kidneys and eliminate waste.
Creatine is a nonsteroidal, nonprescription muscle-enhancer taken orally prior to working out.
Some users believe it gives them a training edge by helping increase body weight and muscle energy. Anytime you have a supplement that is used to enhance your performance, it's going to be controversial. People want to know if it actually improves your performance, what it does to your body and if it's safe. In a study completed as part of his dissertation at the University of Virginia and defended in December, Powers gave creatine supplements to 16 subjects and placebo supplements to another 16. During a five-week period, Powers took muscle samples and readings of cellular water content from the subjects.