I've divided this message into sections with headlines. Please let me know if you would like to be removed from this mailing list or I should add anyone. You will need your KeyServer name and password in order to download the updates.
Detailed instructions are available on the download page.
Note that this update includes new Transcription Factor data, Enzyme files, and Matrix files. Note that version 4.05 introduces an important modification that accommodates recent changes to NCBI's blast servers. Blast functions from within LaserGene will not work unless you update. Previous versions did have a workaround, but that is not a permanant solution. While you're downloading the software, please update to the most recent KeyServer Client software, also found in the software archive section of our web site.