Study designs and statistical methods include twin studies, family studies, population-based association studies, segregation analysis, and linkage analysis. Working knowledge of molecular genotyping and phenotyping, genomics, and bioinformatics related to genetic testing provided. Concepts of multigenic diseases, chromosomal mapping, quantitative traits with emphasis on diseases of major public health impact. Interaction between inheritance and nutrition. Focus on mouse genetics.
Discussions focus on interpretation of results.
Laboratory sections apply methods to data provided by instructor. Monks Theory and application of statistical techniques used in genetic epidemiology. Includes discussion of association studies, linkages and segregation analyses. Examples stressed with reference to assumptions and limitations. Attitudes and behaviors toward health, illness, and disability are studied using historical, contemporary, and cross-cultural case study material.