Antidepressants don t all work in the same way. It may take several months to find the right medication and dosage, but doctors today can choose from a wide array of drugs to maximize benefits and minimize side effects. A doctor can determine which drug is best for you, based on your symptoms. If insomnia is a problem, for example, you may need a medication that is more sedating. Depression accompanied by lethargy and fatigue may respond better to Prozac or Wellbutrin, because of their stimulatory properties.
Antidepressants can have side effects, especially in older persons who metabolize drugs more slowly.
For example, certain tricyclic antidepressants, such as Elavil, can produce cardiovascular side effects and should probably be avoided if you have heart disease. Your doctor will probably try to minimize side effects by starting you on low doses and building up. If you still experience significant side effects, you should probably try another medication. Spend time with others who make you laugh. Exercise can actually increase positive feelings.