Please conduct a current literature search and check the appropriate current online database for the most recent quantitative information. Aniline is severely irritating to mucous membranes and affects eyes, skin, and upper respiratory tract . Limited data are available on the reproductive or developmental effects of aniline. Human cancer data indicate that there is not sufficient evidence to suggest that aniline itself is a cause of bladder tumors .
Animal studies indicate that aniline causes tumors of the spleen and body cavity.
Exceedance of the RfC does not imply that an adverse health effect would necessarily occur. As the amount and frequency of exposures exceeding the RfC increase, the probability of adverse health effects also increases. Aniline has also been found as a volatile component of black tea. There are tests currently available to determine personal exposure to aniline through the analysis of the blood or urine. Acute inhalation exposure to high levels of aniline in humans has resulted in effects on the lung, such as upper respiratory tract irritation and congestion.