Calcium may not be absorbed and lead to a deficiency. Gonadal insufficiency Amenorrhea, or absence of menstrual periods, is a possible sign of gonadal insufficiency and abnormal function of estrogen and other reproductive hormones. Abnormal function of estrogen can lead to rapid calcium loss from bones. Hemochromatosis Greater than normal deposits of iron in the body, either associated with an injury to tissue or as a hereditary disease which results in over-absorption of iron. Pituitary failure and diabetes mellitus are common symptoms and indicate abnormal function of hormones which can lead to osteoporosis.
Bones are in a weakened state and more susceptible to osteoporosis.
Idiopathic scoliosis Abnormal curvature of the spine resulting in symptoms of back pain and fatigue after sitting or standing for long periods of time. Pain and immobility can result in lower bone density from lack of weight bearing activity. A disease of abnormal insulin secretion, elevated blood glucose levels, and end-stage complications to the kidneys and other organs and body tissues. In response to the complex stresses of IDDM on the body, glucocorticoids are released from the adrenal glands. Over time, this can lead to increased risk of osteoporosis.