The testes may atrophy after the initial period of swelling. Scrotal enlargement or infection of the skin over the scrotum may be seen. Eye inflammation may be seen in either sex. There is a kit available to veterinarians for testing in their office. It is usually best to retest any dogs found positive on this test with other testing methods since there is a fairly high rate of false positives using the in-house test kit.
Brucellosis is very difficult to treat successfully.
A combination of minocycline and streptomycin is thought to be most effective but is expensive. Tetracycline can be substituted for the minocylcine to reduce costs but also lowers the effectiveness of treatment. All infected animals should be neutered or spayed to prevent sexually related transmission. All infected animals should be considered to be lifelong carriers of the disease, even if treated. It would probably be best not to breed dogs without testing both the male and female for this disease.