There have been occasional reports of punctate cataracts. These minute opacities in the lens in no way interfere with vision. They are not progressive. Cardiomyopathy is an uncommon but reported condition in clumber spaniels. Pyruvate dehydrogenase deficiency is a rare condition in clumbers.
Conclusive diagnosis is by muscle biopsy.
It is quite common for young female clumbers NOT to have their first estrous cycle until they are 12 to 14 months old. This is not unusual, and should not be cause for concern. Many clumbers are natural whelpers, but uterine inertia may necessitate cesarean section. Anesthesia in clumbers should be straightforward, given normal precautions. Rarely, excessively short muzzles or an elongated soft palate may make anesthetic recovery a bit more comparable to brachycephalic breeds.