Many girls may have distinctive characteristics, while some girls may show few. Turner's Syndrome occurs in 1 in 3,000 live female births. Short stature is almost a consistent finding in Turner's Syndrome, the cause of which is multifactorial, including intrauterine growth retardation, gradual decline in height velocity in childhood, absence of pubertal growth spurt and to end organ resistance resulting from skeletal dysplasia. Patients with Turner's Syndrome have abnormal body proportions characterized by markedly shortened lower extremities. The ultimate height range is between 55 to 58 inches.
Cardiovascular anomalies are common and the most clinically frequent is coarctation of the aorta.
The most common anomaly is a horse shoe kidney. There is an increased frequency for chronic lymphocytic thyroiditis and diabetes mellitus or carbohydrate intolerance. Patients with Turner's Syndrome are prone to keloid formation. The prevalence of mental retardation appears to be no greater than that in general population. However, many patients have a specific deficit in special ability and frequently exhibit gross and fine motor dysfunction.