Experimental work in animals has suggested that serotonin has a role to play in this disorder. It is also worth noting that other brain mono-amine neurotransmitters have been implicated as well. It is perhaps therefore advisable to exclude commercial divers from being passed fit. The case for sports divers and those performing shallow dives only is less clear but bear in mind previous comments regarding continuing disorders. TCAs - unlike SSRIs these have significant side effect profiles including sedation and slowing of reaction times.
Cardiac toxicity is another consideration.
MAOIs - the significant side effect profile excludes their use in divers for the same reasons as for TCAs but there is the additional complication of the interaction with food substances and other medications. Other antidepressants - SNRIs and NARIs are newer drug groups with as yet insufficient information regarding their effects to fully comment on their safety in divers. That being said the same provisos already mentioned for SSRIs should still hold. It should be noted that diving itself increases the potential toxicity of lithium. Antipsychotics - as with the TCAs antipsychotics cause psychomotor slowing and adversely affect reaction times.