This course provides an overview of the macromolecules and small molecules that are the key to all living systems. This course is part of a two semester sequence with BIOC 407 that provides an introduction to biochemistry, molecular biology and genetic engineering. An examination of the flow of genetic information from DNA to RNA to protein. Where possible, eukaryotic and prokaryotic systems are compared. Special topics include yeast as a model organism, molecular biology of cancer, and molecular biology of development.
Current literature is discussed briefly as an introduction to techniques of genetic engineering.
BIOC 307, BIOL 205, or equivalent. The interactions between biomolecules are discussed in a system-based approach that stresses quantitative and structural characterization. The molecular basis of cancer is covered in lectures and discussion of the scientific literature. The principal topics are cellular and viral oncogenes and tumor suppressors, including their identification, function, and roles in cellular transformation and malignant progression in humans and in animal model systems. A detailed consideration of the structure and function of proteins and enzymes.