I mean, it is still minimal but not no findings at all, but there is on immunofluorescence something that s IgM deposits. We are not sure whether it is an entity in itself. It s still called minimal change with IgM deposits, but it seems like these patients don t respond as well as pure minimal change. I talked about this, clinical presentation. I didn t mention that they can have such bad edema that there can be skin breakdown with oozing of fluid, such as in the scrotal area, the vulvar area in girls, and that would require admission and IV albumin to try and mobilize the fluids a little bit, out of the interstitium back into the vascular tree.
Blood pressure is normal or low.
We talked about it. The diarrhea, I mentioned because they can have intestinal edema, intestinal mucosal edema. Okay, another common complication, perhaps the most common nowadays, is thrombotic events, thrombosis. They are very hyper-coagulable, nephrotics, and they can have thrombotic emboli or just deep vein thrombosis. Any nephrotic shouldn t have deep vein sticks or arterial sticks.