I've seen a couple of dermatologists who have diagnosed different things. One called it dry skin and prescribed Lac-Hydrin 12 percent. This didn't help. The other dermatologist didn't really give me a diagnosis, but prescribed an antibiotic ointment and oral medication, which didn't help either. Dry, cracked hands are a common and frustrating problem.
Cold weather can cause it.
Hands that are frequently in water often will become dry and cracked. This can be very painful when the cracks are open. Some suggestions to keep your callused areas from cracking would be to keep your hands covered and warm while out in the cold and to keep them dry and moisturized at all times. Try applying petroleum jelly or mineral oil to your hands in the morning and at night. Wearing a clean pair of white gloves over night after coating your hands will soften the hard, dry areas thereby preventing cracking and bleeding.