Afternoon activity may occur in mild weather. The peak of foraging and reproductive activity is from late April to early June. Males and females defend territories. May. Clutch size ranges from 6-13, average 8 eggs. There are no reports of predation on this lizard but they are probably taken by coyotes and other mammalian predators, larger avian predators, and possibly snakes.
Adverse weather can result in no reproduction.
The ecology and social behavior of the chuckwalla, Sauromalus obesus obesus Baird. Johnson, C. R. 1965. An ecological study of the chuckwalla, Sauromalus obesus Baird, in the western Mojave Desert. Nagy, K. A. 1971. Ph.D. Thesis, Univ.