Both hold out the hope of causing a significant life extension. Both involve doing something your peers and relatives might not like. I have heard people make up bizarre excuses about why both of them won't work on humans. Both are unnatural. Neither corresponds to an easily packageable product you can sell in a store or by mail.
Calorie restriction is difficult, since dieting is difficult.
Cryonics is easier, in principle. All you have to do is sign some papers initially and send checks regularly, and notify the organization when you seem to be going down. Calorie restriction unquestionably works on rodents and a number of other species. Lifespan experiments on primates are in the works. Other experiments on humans and other primates have reported similar biochemical changes to what happens to the rodents.