Studies and review articles addressing antioxidant, antihypertensive, and ergoloid derivative pharmacotherapy research. Pertinent information was selected and the data synthesized into a review format.
AD is a progressive neuropsychiatric disorder of unknown etiology.
Studies evaluating the possible association between a free radical mechanism in AD and the potential role of antioxidants are reviewed. Understanding the role of antioxidants in AD may suggest alternative agents that have similar pharmacologic activity. Other agents that may have a role in AD therapy include angiotensin-converting enzyme inhibitors, nimodipine, and ergoloid derivatives.