This would have consequences causing duplications and deletions if recombination occurred within it. Because recombination almost never occurs in this region on chromosome 9. You might check a number of extra marker loci to see if they all show the same pattern of inheritance and are all consistent with uniparental disomy. You could even probe the chromosomes with a CF clone in a FISH experiment to confirm that two alleles were present. Assuming that heterozygotes are not at any selective advantage and that the frequency of the disease is not changing, estimate the mutation rate in the cystic fibrosis gene.
Achondroplastic dwarfism is an autosomal dominant genetic disorder of bone growth.
Assuming that mutations in just one gene are responsible for this condition, estimate the apparent mutation rate. This one is so easy that even if we haven't considered it before you should be able to work it out.