Cut section reveals a well demarcated, partially circumscribed, tan- white homogeneous and lobulated tumor in the superior pole, 1.5 cm. This tumor has an almost identical gross appearance to the lymph node or the specimen in part 1. A frozen section is done. Part Block Sect. In addition, the investigation of this neoplasm with alternate cytokeratin such as CAM 5.2 or AE1 alone are suggested to evaluate the immunohistochemical characteristics of this neoplasm.
Additional tissue is available if needed.
Examination of the Toluidine blue stained tissue reveals sheets of large pleomorphic cells with a high nuclear to cytoplasmic ratio. A second population of small lymphocytic cells is admixed with these larger cells. Fine capillaries are interlaced within the section. These findings are similar to those seen on the HE material. Ultrastructural examination reveals large cells with increased heterochromatin and prominent nucleoli , admixed with normal- appearing lymphocytes.