Her father has suffered from a myocardial infarct at 38 year-old, but was still living. Her mother had had five miscarriages. A renal biopsy was arranged, to determine the diagnosis and prognosis, and to decide on treatment, if any. Pathology Light microscopy Two cores of renal cortex containing up to 8 glomeruli are obtained. The non-sclerosed glomeruli are within normal limits.
Arteries are within normal limits and there is no vacuolation of arterial smooth muscle cells.
To access light micrographs, use Figure 1. Foot processes of podocytes are segmentally effaced. Small myeloid inclusions are present in rare glomerular mesangial cells and in a few smooth muscle cells of arterial walls. To access electron micrographs, use Figure 4. A renal biopsy and particularly electron microscopy have been instrumental in establishing the diagnosis in this patient.