Endoscopic lesions can be seen as early as two to three months after surgery and the recurrent disease is almost always localized just proximalt to the ileocolonic anastomisis. Fortunately, the recurrent disease in the distal small bowel does not always cause symptoms. A part of the patients eventually need a new resection because of recurrent disease. 5-aminosalicylic acid, metronidazole and azathioprine have been used in the prevention of symtomatic recurrence. Transverse Colon Mucosal scarring in an inactive Drohn s disease.
Amyloidosis is a rare but severe complication of Crohn s disease.
Secondary amyloidosis can affact multiple organs, a.o. the kidneys, causing nephrotic syndrome and kidney failure. Transverse Colon Sacroilitis and ankylosing spondylitis are the main musculoskeletal complication of Crohn s disease. Descending Colon Diarrhea is nearly always present when this disease affects the colon. Abdominal pain and bleeding are other common symptoms. About one fourth of all patients with Crohn s disease have only colorectal affection.