There are over 80 species of Mastadenovirus with about 40 infecting humans.
Adenoviruses produce mild respiratory infections and conjunctivitis, affecting mostly children.
The termini of the genome are linked by proteins, allowing complete replication. The structure of Adenovirus has been extensively analyzed. The virion is composed of 9 different polypeptides having 8 distinct antigenic determinants. Most of the antigens are on the outer capsid and all show hemagglutinating activity. The replication of Adenoviruses is similar to that of Herpesvirus.