Do not use ephedra if pregnant, nursing, or if you have anorexia, anxiety, bulimia, glaucoma, or cerebral perfusions. Reduce or discontinue use if nervousness, tremor, sleeplessness, loss of appetite, or nausea occur. Prolonged use can weaken the adrenal glands and lead to nervousness and insomnia. Do not use if taking an MAO inhibitor, or any other prescription drug. Not intended for sale or unsupervised use for persons under 18.
Chronic use can lead to rapid development of tolerance and dependence.
Summary Based on historical Chinese usage, ephedra appears to have several health benefits. However, credible research is limited. Given the extent and severity of adverse side effects associated with ephedrine, the principal working agent in ephedra, caution should be taken with its consumption. Before taking any herbal supplement, check with your health care provider. Natural Medicines Comprehensive Database.