I would greatly appreciate any suggestions this list might provide. PPC Native applications are noticeably faster, but not impressively faster. 68040 programs are a little bit faster, but only with Speed Doubler running. I suppose it will be better with the 167MHz 603e, but I haven't installed one of those yet. A chemist here has ordered a board, so I should get a chance to see it.
Compatibility is quite good.
Check the global village web site for the latest drivers for your internal mercury modem. It will only work with the latest drivers. Other than that, I have found only one problem, and this won't affect you anyway. Even if you want one, it's too late now because they're next to impossible to find. Note that if you do attempt to find one, you need a Rev C module to work with the 603e.