Thus, aging could well be caused by an inability of the body to repair itself on a molecular level. During the formation of biological systems, distortions and slips occur frequently. These abnormalities can be catastrophic if they affect DNA, which carries genetic information. Nonetheless, each of our cells appears to require accurate genetic information to thrive. Advancing years are marked by several changes in organ systems.
Connective tissue is the glue that holds organs together and in place.
As we age, it dries out, causing calcium deposits, joint stiffness, loss of skin elasticity and decreased muscle mass that begin to occur at about age 35. This means that more energy is required for breathing, respiration becomes less efficient, less oxygen enters the lungs, and the work of breathing increases. No one knows why or how collagen, an amorphous protein substance, is formed. However, once deposited between muscle cells, it interferes with normal function and reduces the strength of contraction. This is one reason why systolic blood pressure tends to rise with age.