I was able to reduce my intake of Pycnogenol by half after adding lipoic acid to my program. After antioxidants, digestion should be checked. Then, digestive enzymes should be checked. Given the antibiotics that are used in so many of our meat products, everybody should probably be taking pro-biotics periodically. Good digestion is not only important for proper assimilation of nutrients, it is also important for proper elimination.
Constipation can be a major source of toxic chemicals that burden the brain, liver and kidneys.
The next thing is deprenyl. The liquid deprenyl citrate remains a core part of my program. Not only does it raise dopamine levels, but it really does rejuvenate brain cells. You can stop the damage, I believe, with all of the vitamins, minerals, nutrients and antioxidants, but you can't repair the brain without deprenyl. Deprenyl can be tricky to implement in some people.