Recluse bites usually form a red circular area on the skin which sloughs off the skin leaving an open wound which is difficult to heal and may require several months before it is completely healed. Reactions vary in severity, depending on the sensitivity of the individual. Seek medical attention if such a bite occurs. This spider is quite non-aggressive and bites occur most frequently when it is injured or killed. This may happen when trapped in clothing or bedding.
Bites often occur on the buttocks or legs.
They typically produce local pain and itching which may take days or over a week to occur. The bite site may develop a discolored pustulate area that progresses to a necrotic area with an open wound the size of a quarter or larger. Systemic reactions may include rashes, fever, generalized itching, vomiting, diarrhea, shock or death. Surgical removal of the bite site has also been tried but is not generally advised. Nitroglycerin patches are also used.