The trip to Tokyo or Ueno will take about 60 minutes with the other destinations taking 30-40 minutes more. On every Narita Express train there are special spaces set aside for wheelchair bound passengers. There are also bathrooms accessible in a wheelchair. The difficult part about taking either of the trains is that you end up getting off at less well-equipped train stations than you boarded from. The platforms at which the airport trains arrive in Tokyo, Ueno and Shinjuku are equipped with either escalators or elevators.
Attendants are available on all platforms to give assistance.
A direct phone line from the train to the JR's English Language Telephone Service is provided free of charge. Riding a limousine bus into Tokyo is another convenient option. The ticket counter is located in the arrival lounge, although it is high and difficult for a wheelchair bound person to reach alone. The bus departs from just outside the arrival lounge and attendants are readily available to help with luggage. Depending on where you want to go, the trip will take between 70 minutes and 90 minutes, but depending on the traffic it could take an extra hour or more.