People with physical dependence will develop tolerance and need more of the drug to gain the same effect. Withdrawal syndromes differ for various drugs. They may include irritability, nausea, sleeplessness, anxiety, vomiting, stomach cramps and last for a week or more until the drug is metabolised totally or eliminated from the body. Medication may be used to assist some withdrawal syndromes. Indian hemp, from whose fibres paper, clothing, and textiles can be made, is a non-psychoactive strain of cannabis sativa .
Cannabis is presented as marijuana, hashish, or hashish oil.
Hash can be added to tobacco and smoked, or eaten in foods. Hashish oil is the strongest form of cannabis and is used to impregnate cigarette papers and smoked. Methadone is a synthetic opioid which is prescribed for people dependent on heroin. Prescribing methadone is one method of treating heroin dependence and reducing associated personal and social problems. Methadone is taken orally once per day by people registered as heroin-dependent.