Get unregulated, overstimulation of the thyroid. T cells infiltrate the pancreas and destroy the beta-cells in the islets of langerhans. Antibodies are also involved. Virus infection may precipitate. T-cells attack the myelin sheath of nerve fibers resulting in progressive muscle weakness and visual disturbances.
Complexes accumulate in the joints.
Joint cartilage destroyed. Vasculitis and lung injury also occurs. Tc cells are probably also involved.