Classic Dengue has symptoms of fever, chilly sensation, severe headache, nausea, severe bone and joint pain. Dengue Hemmorrhagic Fever has the same symptoms as the classic form, also with internal bleeding and shock. If the patient survives the infection, it causes a sensitization instead of immunization. It is an arbovirus that is transmitted by Aedes Aegypti .
All infections are from a mosquito vector.
There was no threat of the virus in the United States until 1985, when a shipment of tires from Japan arrived that contained stagnant water harboring the larvae of the Asian Tiger mosquito, which could withstand frost. The first recorded outbreak was July 1976 in the South Sudan. Second outbreak, September 1976, Zaire. The incubation period is 2-21 days. The virus contains proteins that mimic the proteins found in the coagulation pathway which causes the coagulation cascade to begin.