Gene therapy need not involve a single treatment to be successful. B. Recommendations for future research 6. Identification of novel genes and determination of their function is a key area of research in reproductive biology for the future. The precise role of senescence genes in malignancy needs to be determined. The ability to transfect mammalian endometrium permits novel interventions to study the relevance of different genes and provides the potential for new targeting therapeutic strategies.
Angiogenesis is a key aspect of reproductive biology.
The role of disordered angiogenesis in common diseases including abnormal uterine bleeding, endometriosis, fibroids, pre-eclampsia and gynaecological malignancy needs to be determined. Implantation is a key area of research for reproduction, being important in infertility, contraception and the establishment of successful pregnancy. The development of cheap, standardised assays for the investigation of Y chromosome abnormalities and their application to large population samples needs careful planning and international co-ordination. Continued research into gametogenesis is of basic interest to reproductive biology. Research into the malignant potential of endometriosis is required urgently in view of the broad incidence of the disease.