Japanese Journal of Clinical Oncology, Volume 28, Issue 03, pp.
Angiogenesis is an essential factor for progression and metastases in solid tumors.
It has been reported that several angiogenic factors play a role in the regulation of angiogenesis. We investigated expressions of VEGF in a series of lung carcinomas with regard to clinicopathological factors. All lesions were resected at surgery. VEGF expression did not correlate with clinicopathological factors such as tumor size or pathological stage, but pathological stage I adenocarcinoma cases positive for VEGF demonstrated a shorter disease-free period when followed up for 48 months than those cases expressing VEGF negatively. This page is run by Oxford University Press , Great Clarendon Street, Oxford OX2 6DP, UK as part of the OUP Journals World Wide Web service.