It can also be severe and life threatening. There are three structures within the glomeruli that can be affected. This is a high level of waste products, such as a substance called urea that is normally filtered into the urine, from the blood. It is a sign of kidney failure. Treatment of the underlying disease or infection may prevent this condition.
Diagnosis is based on several factors.
A renal biopsy , which involves using a special needle to obtain a piece of tissue from the kidney so that it can be examined under a microscope, may be needed to confirm the diagnosis. It is also useful in choosing treatment. Taking corticosteroid drugs over a long period can weaken the bones. Immunosuppressive and cytotoxic therapies can increase a person's risk of infections and cancer. Other side effects depend on the treatment given.