The profile will help you plan how to reach this particular sector. Yes, donors do have needs that they expect to meet with a contribution. It could be a need to do something for the environment, or a need to further a business objective. People donate because they want to, not because you think they should. Next you need to choose the fundraising technique appropriate for your target audiences.
All approaches incorporate the case statement and specific information from the donor profile.
How to Ask There is an art to asking. A good approach is to focus on removing reasons for saying no instead of trying to talk people into saying yes. Answer their unstated questions so that they will concentrate on what you are saying. And it's best if the asking is done by a person who would be seen as a peer by the potential donor. This means that the fundraiser needs to solicit the help of all types of people in the fundraising campaign.