Secretion of bile for the emulsification of ingested fats in the small intestine. Deamination of amino acids with the production of urea as a by-product. While in the pig each lobule is clearly demarcated by connective tissue, in the human liver, demarkation between adjacent lobules is not clear and connective tissue can be seen mainly in the sites that contain branches of the hepactic artery, hepatic portal vein and bile duct. The sinusoids are lined by endothelial cells and phagocytic Kupffer cells . The blood sinusoids receive blood from the distributing branches of the hepatic portal vein and to a lesser extent, from branches of the hepatic artery at the outer margins of the lobule.
Blood moves centrally through the sinusoids toward the central vein.
The central vein drains venous blood away from the lobule, into a sublobular vein that courses along at the base of the lobule. Sublobular veins unite to form larger veins which can be seen in solitary as tributaries of the main hepatic vein. The sinusoids are lined by endothelial cells and phagocytic Kupffer cells . The blood sinusoids receive blood from the distributing branches of the hepatic portal vein and to a lesser extent, from branches of the hepatic artery at the outer margins of the lobule. Blood moves centrally through the sinusoids toward the central vein.