S-AMe is a metabolite of the amino acid methionine, and is found naturally in the body. It has been widely used in Europe for many years as a treatment for depression, asthhritis, and cirrhosis, as well as for fibromyalgia. It is extremely safe and has minimal side effects. The main drawback to treatment with S-AMe is its expense. It is now available in the U.S. in 200 mg tablets.
Current price is about two dollars per tablet.
The starting dose is three to four tablets a day taken on an empty stomach for the first month, and then the dose is decreased to the lowest number of pills required to prevent pain. These injections contain magnesium, calcium, Vitamin C, and some B vitamins. They are given by slow injection into a vein of the arm over a few minutes time. A diet which emphasizes elimination of simple sugars and encourages moderate protein intake at the expense of carbohydrates may help many patients. There are a few other dietary modifications which may be of value.