There are different types of EDS and these were reclassified in 1997 into six major types, they are classified according to their symptoms and signs with each type running true in a family thus an individual with one type will not have a child with a different type. Collagen provides strength for the different parts of the body. Some types are firm to give support, others are elastic to allow movement and strength, and still others resemble glue binding protein together. Consequently, if it is defective, it can produce many problems. EDS is known to affect both males and females of all races and ethnic backgrounds.
Diagnosis is based on the presenting symptoms and family history.
Diagnosis can be delayed or overlooked in some cases as they do not fit conveniently into a specific type. A skin biopsy may be taken to study the connective tissue. When skin is over-stretched it still retains normal elastic recoil and snaps back once released. This is best tested at the neck, elbows or knees. Gaping, 'fish-mouth' or 'cigarette paper' scars follow minimal trauma over sites of bony prominence and areas prone to trauma such as the forehead, chin, elbows, knees and shins.