Silibinin Plus is a powerful combination of the two. Purified flavonolignan extracts from the fruits of the milk thistle contain silymarin, an isomer mixture of silibinin, isosilibinin, silicristin and silidianin. Silymarin and its main isomer silibinin, respectively, have been shown to possess antioxidant properties thus preventing lipid peroxidation and membrane destruction in cells. In addition, protein biosynthesis and cell regeneration are accelerated in the damaged liver leading to restoration of the liver functions. It has also been shown that silymarin inhibits leukotriene production which explains its anti-inflammatory effect and that it has an antifibrotic action.
Clinical trials confirm the positive effects found in experimental studies.
Thus, silymarin is nowadays not only the best documented drug for liver therapy but also one of the most intensively investigated plant extracts with known mechanisms of action. Silymarin protects the pancreas Silymarin can be extracted from the milk thistle, and silibinin is the main component of the plant extract. Possibly due to their antioxidant and membrane-stabilizing properties, the compounds have been shown to protect different organs and cells against a number of injuries. Thus liver, kidney, erythrocytes and platelets have been protected from the toxic effects of alcohol, carbon tetrachloride, cold ischemia and drugs. In addition, silibinin protects the exocrine pancreas from CiA toxicity.