You won't catch as many fish as you would had you hired a guide, but you'll find tremendous satisfaction in doing it yourself. The Keys boast two state parks with excellent bonefish flats convenient to the campsites. The first, Long Key State Park, contains sixty campsites literally right on the water. Even anglers without boats can catch bones here by wading. The flats at John Pennekamp Coral Reef State Park on Key Largo require a boat, but just about any boat that will float in shallow water will do, since you can wade once you get to the flats.
Canoes work quite well.
Both motor boats and canoes are available for rent at Pennekamp. The visiting angler needs to know where and when to look, what to look for, and what tackle and techniques to use. On Long Key, look for bones on the flat directly in front of the campground. Also, try the flats in Long Key Bight at the eastern end of the key. A technique that I find effective involves blindcasting into deeper water while I search the shallows for fish that I can see, either cruising or tailing.