There are seven major disorders listed in this category. This is the most common chromosomal abnormality. The afflicted children usually manifest ligament laxity, hypotonia, endocrine disorders, premature ageing, mental impairment to varying degrees and an inclination towards heart disease. If surgery is planned preoperative cardiac evaluation is essential. Turner Syndrome - 45, XO affecting females.
Afflicted girls exhibit some or all of the following symptoms.
Boys suffering this disorder differ from the Turner Syndrome girls in that they have normal sexual genotypes. Other symptoms are similar including a high risk of malignant hyperthermia if anaesthetics are used. This is a chromosomal abnormality. Afflicted children are hypotonic and intellectually impaired. They develop a 'floppy' appearance and gait and tend towards obesity.