Do not drink the water from rivers and streams without first boiling for at least one full minute to be safe. Check for current fishing regulations. They change periodically. The Pacific Crest Trailhead crosses Highway 96 at Seiad Valley and is about midway between Southern California and Washington State. Please do not feed bears or leave food out which attracts them to your campsite.
Bears can be dangerous.
Swim and boat at your own risk. The river and stream currents are extremely dangerous. Always use lifejackets. Watch for changing road conditions especially in spring and winter. Please be considerate of local drivers who are not sight-seeing by pulling over when they are close behind you.