Processing of the harvested crop does not result in any residues that are not formed in animals, so additional toxicity studies on residues are not required. There is no evidence from any of the studies to suggest that cyhalofop-butyl is an endocrine disrupter. Based on the rapid degradation of cyhalofop-butyl and its high tendency to sorb to soils, no surface water or ground water contamination is expected. This agrees with EPA Tier I modeling carried out on cyhalofop-butyl. Therefore, drinking water will not be a significant route of exposure.
Dietary exposure is very low as previously mentioned.
In addition, a rotational crop study showed no carryover of cyhalofop-butyl related residues in any representative test crop. There are no residential uses for this compound. As a result, the only potential for exposure is dietary, which is acceptable. Therefore, aggregation of exposures is not necessary. E. Safety Determination 1.