Contraindications Documented hypersensitivity Interactions None reported Pregnancy B - Usually safe but benefits must outweigh the risks. Topical antihistamines - Act by competitive inhibition of histamine at the H1 receptor. For prophylaxis and symptomatic relief. Contraindications Documented hypersensitivity Interactions None reported Pregnancy C - Safety for use during pregnancy has not been established. Contraindications Documented hypersensitivity Interactions None reported Pregnancy B - Usually safe but benefits must outweigh the risks.
Corticosteroids modify the body's immune response to diverse stimuli.
Glucocorticoids inhibit edema, fibrin deposition, capillary dilation and proliferation, phagocytic migration of acute inflammatory response, deposition of collagen, and scar formation. Used topically, they can elevate IOP and cause steroid-response glaucoma. In clinical studies of documented steroid-responders, fluorometholone demonstrated a significantly longer average time to produce a rise in IOP than dexamethasone phosphate. In a small percentage of individuals, a significant rise in IOP occurred within 1 week. The ultimate magnitude of the rise was equivalent.