Clinical Signs, Diagnosis, and Treatment Canine Parvovirus 2. The myocardial form is rare because of widespread protective maternal antibody in neonatal puppies. The enteric form can cause a rapidly progressive fatal disease characterized by vomiting, hemorrhagic diarrhea, severe dehydration, and shock. Aggressive therapy includes crystalloid and colloid fluid support, broad-spectrum antibiotics eradication of intestinal parasites, antiemetic therapy, and nutritional supportive. Puppies must be monitored closely for complications, which may include hypoglycemia, hypokalemia, hypoproteinemia, or protracted vomiting secondary to intussusception, acute pancreatitis, or reflux esophagitis.
Aggressive management can result in full patient recovery and long-term immunity.