Both methods are safe and effective if proper service delivery guidelines are followed. The only condition restricting use of ECPs is established pregnancy.
Conditions restricting regular use of IUDs also apply to their emergency use.
The second dose must be taken 12 hours later. The main side effects of ECP treatment are nausea and vomiting. Side effects are more common with combined ECPs regimens than with progestin-only ECP regimens. These side effects generally do not last more than 24 hours and may be reduced in some women by providing anti-nausea medication before ECP treatment. The treatment schedule is one dose within 72 hours after unprotected intercourse, and a second dose 12 hours later.