Some medicines and foods can decrease the amount of digoxin your body absorbs. Taking these medicines or eating high-fiber foods too close to the time you take your digoxin may result in too little digoxin in your bloodstream to help your heart. For this reason, it is better to take digoxin on an empty stomach. Check with your doctor before taking any of the medicines listed above. If your doctor says it's okay to take these medicines, keep two hours between a dose of digoxin and a dose of these medicines.
Digoxin interacts with many other drugs.
Always talk to your doctor or pharmacist before you add any new medicines. The digoxin dose needed to treat heart conditions isn't the same for every patient. Your doctor may do a blood test to make sure you have the right amount of digoxin in your body. To be right, this blood test has to be done at least six hours after your last dose of digoxin. For this reason, you should tell your doctor when you normally take your digoxin.