Other associated conditions include Paget's disease of bone, sickle cell anemia, and Ehlers-Danlos syndrome. These streaks, which are breaks in Bruch's membrane, have lead to choroidal neovascularization in this case. A peau d'orange pigmentary change is also noted temporally. Pseudoxanthoma elasticum is a dermatologic condition but gastrointestinal and cardiac abnormalities may also be associated with this entity. Serpiginous Choroiditis Serpiginous choroiditis is a rare bilateral inflammatory disorder.
Acute lesions are grayish-white and occur at the retinal pigment epithelium or choroidal level.
Chronic lesions show pigmentary changes. Acute lesions occur at the edge of the chronic lesion. Choroidal neovascularization may occur in these patients. Vein Occlusions Central retinal vein occlusion is a common retinal vascular abnormality usually seen in patients over 50 years of age. A thrombosis of the central retinal vein in the area of the lamina cribrosa is commonly seen on histopathologic examination.