All chemicals are toxic under some conditions of exposure.
Carcinogens Operational Definition of a Chemical Carcinogen Ability to produce neoplasms in animal bioassay. Determine the forms of toxicity that can be caused by the chemical of interest, and determine how vulnerable humans may be to toxic effects. What is the expected exposure or dose expected for members of the receptor populations of interest. The results of most risk assessments are scientific hypotheses that are not generally testable with any practicable epidemiological method. TI score poor predictor of relative cancer risks or noncancer hazards calculated using EPA s standard regulatory risk assessment approach.