Cognitive impairment is commonly feature of multiple sclerosis.
Conflicting results however have been reported previously about its pattern. The cause of this might be the heterogeneity of examined patient groups. This study was set up to investigate the cognitive skills of a homogeneous group of secondary progressive MS patients, and to examine the relationship of this impairment to MRI parameters. The studied group consisted of 44 MS patients. The results showed the presence of deficits of attention, memory, planning abilities, problem-solving and conceptual reasoning, which are all frontal functions, in a subgroup of MS patients.