The study reveals that central giant cell granuloma has a predilection for females, with 6 females and 3 males. The mean age of occurrence was found to be around 30 years ranging from 7 years -47 years. Posterior region of the mandible is effected in 4 out of the 5 cases. 2 patients who showed large aggressive lesions were treated with resection and reconstruction. One aggressive lesion showed recurrence after 4 years.
Conclusion Occurs predominantly in females.
Posterior mandible is the most common region Pleomorphic clinical behavior ranging from slow growing to aggressive. Introduction Central Giant cell lesions are aggressive, highly recurrent, very vascular, rapidly growing with undefined etiology and are clinically poorly defined. Because of such type of nature of these lesions a surgeon's treatment of choice is radical resection. However, complete removal of these lesions by enucleation has not resulted in any recurrence in seven cases observed at our institute for a five year period. Patients were evaluated for age, sex, location, treatment and postoperative recurrence.