Early recognition and appropriate treatment is crucial. These infections most commonly occur in patients who are debilitated, immunocompromised, or diabetic or in corneas with an underlying pathologic condition. E coli rarely is found in the normal flora of the conjunctiva. It most commonly is seen as a source of infection in ophthalmia neonatorum. E coli endophthalmitis is a rare complication of E coli septicemia.
Antimicrobial resistance occurs through plasmid-mediated determinants.
These multiresistant plasmids can be transferred by conjugation. It has a poor prognosis, and early diagnosis and treatment are essential to retain useful vision. These infections most commonly occur in patients who are debilitated, immunocompromised, or diabetic or in corneas with an underlying pathologic condition. Exogenous endophthalmitis usually is associated with trauma or intraocular surgery. In endogenous endophthalmitis, urinary track infection was the most common primary site of infection and nearly all patients are diabetic.