Ferrets can not survive out in the wild. It is thought that ferrets have been domesticated for over 2500 years. Vaccinations Ferrets require only two vaccinations, both of which are extremely important for the life of your ferret. Ferrets require Fervac-D for canine distemper. This shot is required at least twice, three weeks apart, for a young ferret or a ferret with unknown vaccination history, then once a year every year afterwards for the life of the ferret.
Canine distemper is extremely contagious.
Keeping your ferret indoors is no protection against this deadly disease. If you so much as come into contact with an infected animal, or even where one has been, you can take it home on your clothing to your ferret. Vaccination is the only protection, there is no cure. Ferrets also require Imrab-3 for rabies. Ferrets are unlikely to come into contact with rabies, and even if they do, have only slim chance of shedding it in their saliva.