Current research in my laboratory is focused on the effects of cocaine on apoptosis in the placenta and amnion. In addition, I have performed collaborative work with Dr. Barbara Sanborn in the Department of Biochemistry and Molecular Biology on basic mechanisms of myometrial contraction. Clinical research interests have included the effects of cocaine on pregnancy outcome, preterm labor and preterm rupture of membranes. More recently, I have completed studies on quality of life issues in pregnant women and in residents in obstetrics and gynecology. Students in genetic counseling would gain experience in the design and execution of studies relating to a wide range of prenatal diagnosis issues.
Current study includes factors influencing perceived pain with amniocentesis.
Thesis ideas include cultural differences in utilization of prenatal diagnosis in the Southeast Asian population, knowledge and utilization of folic acid in two diverse populations in Houston, and survey of prescription medication use during pregnancy. Oxytocin-stimulated responses in a pregnant human immortalized myometrial cell line. Quality of life assessment in pregnant women with the human immunodeficiency virus. The effect of cocaine on mitogen-stimulated lymphocyte proliferation in pregnant women. Oxytocin-stimulated capacitative calcium entry in human myometrial cells.