These types have different characters. Multiple plasmacytomas are multiple myeloma by definition. Like any cancer, the particular reason why one person gets a plasmacytoma and another does not remains unknown . Routine X-rays are a minimal risk. Men and Women get the disease in equal numbers.
Carcinogens are chemicals that increase the risk of cancers.
They are suspected of causing a gene disturbance in multiple myeloma, leading to an uncontrolled growth of plasma cells. Cigarette smoking and alcohol intake do not appear to increase the risk. At this time, besides being prudent about not exposing one's self to unnecessary radiation or carcinogens, there is no known way of preventing plasma cell cancers. This of course depends upon it's location, and whether it is in bone or the soft tissues. There can be compression of nerve roots in the spine from a growing tumor.