Routine histologic sections are not serial sections 5. Comedo type and tumor size greater than 2.5 cm have high frequency of residual disease. Clinical and pathologic predictors. The diagnosis of well-differentiated tubular carcinoma is suggested by the infiltration of adjacent adipose tissue and loss of lobular architecture of the normal breast. An excised predominantly fatty breast tissue.
Cross sections reveal well-circumscribed, multinodular lesion extending to the border with blue ink.
DCIS extends to the inked border. Tumor cells are covered by ink and reveal hyperchromatic, slightly crushed nuclei right at the surgical margin. Coagulative necrosis is evident on the inked border.