Anthrax can form spores and remain dormant for decades. The infection usually starts as a skin pustule that disseminates widely throughout the blood vessels. If airborne spores are inhaled the disease is particularly severe. Simple antibiotics are effective therapy. It can occur in all parts of the world but is most associated with Asia although recent epidemics have been in South America.
Cholera produces torrential diarrhea and vomiting.
The disease spreads from feces to water. The patient dies from fluid loss unless Intravenous fluid replacement is given. Vaccination can prevent it. Maude Abbott Abnormalities of development of the heart occur during gestation due to misalignment of the vessels, cavities and septa that form in the embryo. Congenital abnormalities were first noticed in the 18th century with dissections by Farre in 1814.