This is followed by fine lines and later by coarse lines, which become deeper as the skin undergoes greater structural changes. These changes are followed by alterations in color and texture. The skin is mottled and gray to yellow in color with areas of red spots and dilated veins. Brown spots appear on the hands and face, and the skin becomes thin. Structural Changes Structural changes are due to changes in the collagen and elastin under the skin's surface layer and later by changes in the surface itself.
Collagen decreases in the dermis which causes sagging.
This is followed by a loss of elasticity, which causes further sagging and lack of resilience in the skin. The number of fibroblast which are responsible for new skin growth also decreases. The skin loses its ability to respond to physical, chemical and emotional stress. The immune response decreases and the ability to dissipate heat is lost. Sensitivity to heat and cold decreases.