According to the National Institute of Neurological Disorders and Stroke, Rett syndrome affects 1 in every 10,000-15,000 female newborns with symptoms usually beginning between 6 and 18 months. Because Rett syndrome only occurs in females, it s believed to have a genetic basis. There is no cure, but there are several things that can be done to manage the symptoms. Orthopedic and learning disabilities, as well as seizures, can be managed with appropriate treatment, and a special diet may be necessary to maintain a healthy weight. Most people with Rett syndrome live at least into their 40 s.
Death is usually a sudden, unexplained event, presumably due to some sort of brain dysfunction.
Back to top Fragile X syndrome Fragile X syndrome is linked to the X chromosome and occurs only in males. It is the second most common cause of mental retardation after Downs syndrome. Boys with Fragile X often have a long face with a large chin, large floppy ears, and enlarged testes. Many researchers believe that there is a relationship between Fragile X syndrome and autism since they share some of the same neuroanatomical features, including abnormal cerebellar development and signs of brain stem dysfunction. Some individuals develop seizure disorders.