Chemotherapy can affect the kidneys.
Drinking plenty of fluids is the most important thing you can do. Ten to twelve large glasses of fluids a day is suggested for the day before chemotherapy and 3 to 4 days after chemotherapy. This includes water, fruit juices, and soft drinks. Your doctors and nurses will be watching the function of your kidneys through urine specimens and blood work. Some chemotherapy may cause your urine to change color.