In diving, we start at the surface with the partial pressure of nitrogen in the tissues equal to the partial pressure of nitrogen in the air we are breathing. In general, tissues with the highest blood flow take up nitrogen the fastest.
Different tissues can tolerate different supersaturation ratios.
In diving, when we dive within the limits of our dive tables or decompression computers, we ensure that no tissue ever exceeds its critical supersaturation ratio, as calculated by the mathematical model.