They prefer to drink by licking off small drops, but they can also drink from a small bottle or a shallow dish. The latter will become dirty with urine and shavings though. They clean their fur very frequently and with great care. This regularly includes scratching. Besides Mus minutoides also Mus musculoides , in German Afrikanische Zwergmaus , and in Dutch Afrikaanse dwergmuis .
Breeding is said to work best in groups of about ten animals.
All females in the group breed. 15 days the pups are weaned. Females can have litters every three weeks. An age 1.5 to 2 years is reached. So such a pairing can work.