Do not suddenly stop taking pimozide. You may need to gradually reduce the dose. Only stop taking pimozide on your prescriber's advice. You may get dizzy or drowsy. Do not drive, use machinery, or do anything that needs mental alertness until you know how pimozide affects you.
Alcohol can increase dizziness and drowsiness.
Avoid alcoholic drinks. Do not drink grapefruit juice products while taking pimozide. An ingredient in grapefruit juice can increase the chance of developing serious heart problems from pimozide. If you are going to have surgery tell your prescriber or health care professional that you are taking pimozide. Therefore, it should not be administered to nursing mothers or to women of child-bearing potential, particularly during the first trimester of pregnancy, unless, in the opinion of the physician, the expected benefits of the drug to the patient outweigh the potential risk to the fetus or child.