One non-randomized study on humans has shown that forskolin can reduce blood pressure and improve heart function in people with cardiomyopathy . A small double-blind study found that inhaled forskolin could decrease lung spasms in asthmatics compared to placebo. 13 Most studies have used injected forskolin, so it is unclear if oral ingestion of coleus extracts will provide similar benefits in the amounts recommended above. Until topical preparations of pure forskolin are available for people with glaucoma , an eye bath can be prepared using the fluid extract. It is imperative to maintain sterile conditions so as not to cause eye infections during this procedure.
Coleus is generally free from side effects.
It should be avoided in people with ulcers , because it may increase stomach acid levels. It could also theoretically cause a problem in someone with low blood pressure, though this has not been documented. Direct application to the eyes may cause transitory tearing, burning, and itching. The safety of coleus in pregnancy and lactation is unknown. Certain medications may interact with coleus.