PepSets, based on the Multipin synthesis system, permit the simultaneous synthesis and screening of large numbers of peptides. PepSets consist of blocks of 96 individually synthesized peptides, two of which are carefully selected control sequences. Cleaved controls are assessed for purity by reverse phase HPLC and peptide content quantitated by amino acid analysis. A full report is provided with each set of peptides including a summary of the quality control results.
Confidentiality is guaranteed.
Partial PepSets of less than 94 peptides can also be purchased. PepSet peptides are available with a variety of chemical modifications including acetylation, biotinylation, phosphorylation and cyclization. Other options will be considered on request. For the production of solution phase peptides there is a choice of C-terminal endings, including acid and amide, depending on intended peptide application. The cleavable bond is incorporated onto the pin surface as a preformed ester derivative of the C-terminal amino acid.