Isolation, inactivity, lack of enjoyment, and negative thinking spiral. There is yet another vicious circle. If you are depressed, you may feel unloved and rejected. In part, your perception may reflect your own negative thinking. But it's probably not all in your head.
Depression often causes actual rejection subtle or overt.
Depressed persons speak less often and more slowly, with lower volume, more silences, and greater hesitancy. They take longer to respond to the remarks of others. They show less eye contact and don't smile as often. Their faces are relatively devoid of animation. They don't gesture or nod their heads frequently.