The lines signify a mortal enemy and each Good, Neutral, and Evil sides are allied together. These conflicts will stay constant in Horizons always and will be the center of political unrest. Howveer, one must remember that Horizons' focus is trading, politics, traveling, and quests, not combat. In fact, combat will not be completely controllable and conducted through cut-scenes. This will cause other tasks like skill building, role-playing and politics to be a larger concern for the gamer rather than consistently battling.
Deities also play a large portion in a character's future in Horizons.
With a choice of eighteen overall, one can choose to worship a god and experience its pros and cons. Or one can stay agnostic with no positive and negative effects. For example, if a person chooses the correct deities, one can have an experience bonus, less painful resurrections, or better magical capabilities. However, things are not as easy as selecting a god and experiencing its blessing. Piety is a new feature in Horizons that role-playing games in the past have not had.