The second, is choose your electives carefully. Pick subjects that fit in with what you want to do. For example in my case, it would have been wise to take four or five business courses. Another possibility is to choose a language and form a concentration. I was the successful candidate for two exciting positions simply because I had a working knowledge of a language that the employer didn't.
Computers are a good complement to an English degree as well.
I took one introductory computer course, and when I graduated a was asked to apply for a number of technical writing jobs. The third is never discount a position because you assume you are not qualified. I apply for every job that interests me because I have nothing to lose and everything to gain. Sometimes, they have a list of qualifications and I only meet one or two of them. A skillfully written cover letter can make all the difference here.