Typically, it is recommended that people start with 100 to 200 mg of Grapenol or Pycnogenol daily for about a week, and then switch to a maintenance intake of 50 milligrams per day. Masquelier, Jacques, Plant extract with a proanthocyanidins content as therapeutic agent having radical scavenging effect and use thereof. Stabilisation du collagen par des oligomeres procyanidoliques. Bioflavanols and their application. Alfa Omega Publishers, Rome, 1993.
Condensed tannins scavenge active oxygen free radicals.
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