Three leaves arise from the plant base. Leaves are simple but deeply lobed. Achenes are very hairy. Mature achenes form aggregates. Seeds are carried away from the parent plant by ants and rodents.
Ant dispersal is most successful for establishment in young sparse populations.
Species associated with sharp-lobed hepatica are those found in upland mesic deciduous forests. Although an early vernal species, it is shade tolerant. After flowering, the overwintering leaves become senescent, and new leaves are produced. Sharp-lobed hepatica remains green when all other herbs have senesced in the fall.