Nevertheless, the simplicity of these mechanisms suggested that it might obtain in genetic systems other than those of mitochondria. To test the possibility that one or more unusual forms could exist in nuclear or bacterial genomes, the structural correlations inferred above were used to search the entire sequence database. This finding suggests that some normal tRNAs can adopt the alternate folding pattern of the unusual mt tRNAs. Whether the non-tRNA genes possessing these features have any biological significance is also of great interest. Yokogawa, T. et al.
Acids Res .
Acids Res .