Bigger antigens cause bigger responses.
Each molecule is specific for one antigen, but also possesses secondary biological activities. Extravascular tissues throughout the body, including lymph nodes, spleen, bone marrow, thymus gland, and MALT tissue, producing lymphocytes. Certain cells go through a series of events to process the antigen, which in turn sets off a cascade of events that includes both cellular and humoral elements. This result includes swelling, warmth, redness, and pain in the involved tissue. Avascular tissue is more at risk for having negative effects, particularly the transparency of the cornea.