Initially, model systems are used and with time other systems and progressively more complex versions of the initial model systems are brought into the program. Thus studies on new system benefit from the technique developments and conceptual advances achieved through the investigation of the prototype systems. The overall core program which consists of several subprojects, is sufficiently developed to serve as an illustration of how several of the BRLC research objectives are developed and put into operation. This program is an example both how progressively more complex systems are built into the program and how molecular biophysics provides a building block for program projects that encompass other branches of biology. The following is a brief list of the sub-projects that make up the heme protein core program.
Blood substitutes program project.
This core program is not as yet as well developed as the hemeprotein core program. It consists of several subprojects some of which are in early stages of development. It is anticipated that with the personnel and technical capabilities available this program will spawn program projects of the same depth and quality as in the hemeprotein core. This core program has already attracted several outside collaborators of outstanding stature. The combination of cellular and molecular biophysics helps make some of the program projects truly unique.