Abdominal pain is reported to be a common feature.
Despite intensive research the aetiology remains unknown. Over 36 months we saw in total 19 children and adolescents with symptoms of CFS or idiopathic chronic fatigue. Ages at presentation ranged from 7 to 16.75 years. The duration of the symptoms at diagnosis varied from 3 months to 4 years. Endoscopy of the upper gastro-intestinal tract was performed in 7 and showed evidence of reflux oesophagitis in 6.