Picture to yourself what a Barnes and Noble looks like. This is the model the non-fan is used to. This is the model the non-fan is used to and, if you emulate it somewhat, you will make them feel more at home. Retailers who specialize in alternative comics all report a slower, steadier sell-through. Eightball may sell 200 copies for Million Year Picnic, but it takes two months.
Alternatives have an enormously long shelf-life compared to mainstream comics.
And they're still on the shelf, and they still sell, three or four of each issue a week. With alternative titles, you won't sell 100 in a week, but you will sell them. And they don't lose value, like mainstream titles. Other, more mainstream alternative titles, such as Milk and Cheese, may have an even slower start, but remain steady sellers for months on end. You will obviously start small if you're starting a section like this, but if you order two or three copies of Eightball, and it doesn't immediately sell out, it very likely will within a month or two.