Testosterone supplements inhibit the natural production of testosterone. It can change serum cholesterol levels. It can cause damage to the liver. It may increase the risk of male breast and prostate cancer. Men may experience excessive frequency and duration of penile erections.
Aggressive behavior can result.
In women, there can be a permanent lowering of the voice, excessive hair growth, acne, clitoral enlargement, and menstrual problems. There can be excessive retention of sodium, chloride, water, potassium, calcium, and inorganic phosphates. There can be problems with blood clotting factors and excessive bleeding. The insert in the testosterone cypionate box lists two long pages of information everyone should read before embarking on any hormone replacement therapy. The symptoms of androgen deficiency can occur gradually as testosterone production declines gradually with age.