The discovery of human pluripotent stem cells is a significant research advance and Federal support to American researchers is essential to translate this discovery into novel therapies for a range of serious and intractable diseases. The therapeutic potential of pluripotent stem cells is remarkable - arguably more remarkable than any previous advance in the history of medical science. These cells have the unique potential to differentiate into any human cell type and offer real hope of life-affirming treatments for diabetes, damaged heart tissue, arthritis, Parkinson's, Alzheimer's, ALS and spinal cord injuries, to name but a few examples. There is also the possibility that these cells could be used to create more complex, vital organs, such as kidneys, livers, or even hearts. Some suggest that adult stem cells may be sufficient to pursue all treatments for human disease.
Current evidence suggests that adult stem cells have markedly restricted differentiation potential.
Therefore, for disorders that prove not to be treatable with adult stem cells, impeding human pluripotent stem cell research risks unnecessary delay for millions of patients who may die or endure needless suffering while the effectiveness of adult stem cells is evaluated. We recognize the significant ethical issues that are raised about embryonic stem cell research and we respect the view of those who oppose such research, including some in our own medical school community. However, we are persuaded otherwise by what we believe is an equally compelling ethical consideration, namely, that. We urge you to allow research on pluripotent stem cells to continue with Federal support, so that the tremendous scientific and medical benefits of their use may one day become available to the millions of American patients who so desperately need them. Before you make any decision that would deny hope to millions of patients and their families, we urge you and your staff to obtain a detailed scientific briefing on stem cell research.