It is possible to have both Korskoff's and a dementia. Women can also be affected. They tend to develop Korsakoff's at a slightly younger age than men as they appear to be more vulnerable to the impact of alcohol. It is not yet clear why some heavy drinkers develop Korsakoff's syndrome and others do not, although this may relate to diet. While it remains unclear whether additional thiamine helps people improve once the brain damage has already occurred, it may help prevent further damage occurring.
Any improvement usually occurs within a period of up to two years.
It has been estimated that about a quarter of those affected will make a very good recovery. About half will make a partial recovery and need support to manage their lives. Another quarter will make no recovery and may need long term care. Korsakoff's is likely to continue to progress if the person continues to drink heavily and has poor nutrition. A wide range of skills and abilities will be affected.