Some people get very sensitive to sunlight. Others may get headaches, be dizzy or sleepy, or have some problems hearing. Very few people who take azithromycin get these side effects. However, most anti-HIV medications also cause problems in the digestive system. Azithromycin could make those problems worse.
Antibiotics kill some helpful bacteria that normally live in the digestive system.
You can eat yogurt or take supplements of acidophilus to replace them. Azithromycin is broken down by the liver. It can interact with other drugs that also use the liver. Scientists have not yet studied all the possible interactions. Azithromycin probably interacts with some blood thinners, heart medications, seizure medications, and other antibiotics.