D. a non-competitive inibitor because Km increases and Vmax stays the same. E. an uncompetitive inhibitor because both Km and Vmax appear to decrease. Leu E. Ala, Leu, Phe 27. Your patient enters the emergency room with chest pain and you decide to test his blood for lactic dehydrogenase, creatine kinase, and troponin. The hemolysis was not due to any condition of the patient, but rather due to the fact that you had a hard time collecting the specimen.
Biochemistry is often a valuable in the analysis of genetic mutations of proteins and enzymes.
A genetic mutation of a urea cycle enzyme in a patient resulted in an impairment of liver function in that individual. Others in the family may have similar symptoms. By sequence analysis you have determined that a Serine at position 105 has been mutated to an Aspartic acid. The mutant enzyme has lost some level of activity. A kinetic analysis of the mutant enzyme was performed and compared to the analysis of enzyme at the same concentration from a normal individual.