The prognosis is good, with symptomatic patients being eligible for either laser PTK or corneal transplant. Its genetic defect also has been mapped to chromosome 5q. In this condition, lattice deposits develop in the cornea years after the typical granular deposits have developed. With age, the deposits enlarge and form a corneal haze. The symptoms are similar to lattice dystrophy, with pain and photophobia due to recurrent corneal erosions.
Avellino dystrophy is managed in a similar manner to lattice corneal dystrophy.
For excessive recurrent corneal erosions, PTK with the excimer laser can be performed. For patients with vision loss and unsuccessful PTK, a corneal transplant can be performed. The deposits can recur in the donor cornea. Children of patients with lattice corneal dystrophy should be monitored once they reach puberty since this condition has autosomal dominant inheritance. Three autosomal dominant corneal dystrophies map to chromosome 5q.