We try to identify the PKC regions which most likely by interacting with other proteins mediate translocation to the nucleus. Protein kinase C in the transduction of signals toward and within the cell nucleus. Bradykinin induces rise of free calcium in nuclei of neuroblastoma x glioma hybrid NG 108-15 cells. Localization of nonconventional protein kinase C isoforms in bovine brain nuclei. The nuclear pore complex protein p62 is one of several sialic acid containing proteins of the nuclear envelope.
Citric acid extracts a specific set of proteins from isolated nuclei.
Transport of protein kinase C-alpha into the nucleus requires intact cytoskeleton while the transport of a protein containing a canonical nuclear localization signal does not. Signal transduction and protein kinases. The long way from the plasma membrane into the nucleus. Nuclear translocation of PKC occurs by a mechanism distinct from the mechanism used by proteins with a classical nuclear localization signal. J. Cell Sci.