Generalised fatigue is not a feature of the condition. This results in a decrease in the amount of acetylcholine released by the nerve impulse. It is a genetic condition in which a mutation that can occur at many different sites in the genes for the acetylcholine receptor interferes with their function. This causes muscle weakness which may be present at birth or evident soon afterwards. There is a very weak familial susceptibility to Myasthenia Gravis and to other autoimmune diseases in the families of patients with Myasthenia Gravis of the Lambert-Eaton Myasthenic Syndrome.
Congenital Myasthenia can be autosomal dominant, autosomal recessive or sporadic.
The Association is a National Registered Charity No. 272413. It was established as the British Association of Myasthenics in 1976. In 1991 the Association changed its name to the Myasthenia Gravis Association. Subscription Donations only Contact a Family is a UK charity which helps families who care for children with any disability or special need. We are a main source of information about rare disorders and are able to assist affected adults as well as children.