Some of the neurological diseases that do not fit into other categories may be better off here. Alpers' Alpers' disease or Alpers' Progressive Infantile Poliodystrophy is a rare, progressive neurodegenerative disease of the brain. It is thought to be an autosomal recessive disorder and usually affects children under the age of 5.
Convulsions mark the onset of the disease, followed by dementia, spasticity and monoclonus.
The untreatable disease is fatal and patients usually die a few months after disease onset. Multiple System Atrophy Multiple System Atrophy, a Parkinson Plus syndrome, is a rare deurodegenerative disorder wiht neuron loss in the brainstem, the cerebellar cortex, the striatum, the substantia nigra and parts of the spinal cord. This category includes disorders caused by prions, which are infectious proteins.