Framing designs should be selected to best compliment the artwork, while remaining as neutral as possible. This is the correct procedure and frames should not be selected solely for the interior design considerations. Your artwork should not be hung in direct sunlight or over a source of heat. Non-glare Plexiglas is not recommended, as it is somewhat distorting. If framed with Plexiglas, it should be cleaned with a Plexiglas cleaner and a soft cloth.
Ammonia based glass cleaners can cause Plexiglas to become cloudy.
Never use a spray directly on a frame, spray the cloth instead. When moving a piece of art, always carry the frame by the side rails, never the top rail. When lifting a frame on and off the wall use the two side rails. A qualified framer should remove the dust cover only and the piece examined to be sure no problems exist. Rooms where works of art are to be hung should have weak daylight and must be illuminated with incandescent lighting, which is relatively harmless.