How large this possibility is depends on many factors such as the degree of exposure and health of those concerned. These medications are not without risk of side effects which primarily involve the liver so the risks of prophylaxis has to be weighed with the true risk of developing active tuberculosis. Though we have special antibiotics to cure active tuberculosis, treatment last for several regimented months keeping up with several pills so we prefer prophylaxis whenever feasible. This is especially important if there are any underlying medical conditions that would make someone more susceptible to developing active tuberculosis. For these and additional considerations, the affected individuals should consult their primary physician.
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