Access is gained by undoing three captive thumbscrews and removing the combined top and side panel.
The two parts are connected by an edge connector, which allows the main logic board to be easily lifted out after releasing two catches. This approach makes maintenance or replacement extremely simple. However, the 5.25in. However, a little rearrangement of these would make life a lot easier for anyone trying to add or remove a device. The cage holding the two 3.5in.