These can be visualized by electron microscope in the subendotheial and mesangial areas. Inflammatory mediators are released resulting in a histologic picture of glomerulonephritis. Thus, the identification of the offending agent is of utmost importance. While the use of heterologous protein such as ATG is easily identified, others such as medication may not be as obvious. The objective of medical therapy is to ameliorate the symptoms that result from deposition of the immune complexes in the various tissues.
Antihistamines are useful in controlling urticarial lesions.
Nonsteroidal anti-inflammatory drugs are used to treat fever and minor musculoskeletal complaints. Corticosteroids are necessary to treat the more severe symptoms. Antihistamines - Useful to treat urticaria and pruritus. Some second generation anti-histamines may also reduce the release of vasoactive amines. It is used for treatment of allergic reactions.