Diploid tumors are also more responsive to hormonal therapy.
DNA ploidy of prostate cancer can be determined by both DIA and flow cytometry. Ploidy analysis by DIA offers superior accuracy compared with flow cytometry for small amounts of cancer such as may be found in needle biopsies. DNA ploidy analysis is offered on all prostate cancer specimens processed at Bostwick Laboratories. For specimens processed outside Bostwick Laboratories, we require the paraffin block with the largest focus of cancer to be sent to us. We cut thin sections from the block and use them for ploidy analysis.