If you are currently taking cimetidine and are concerned, consult your doctor. Spironolactone is a drug that belongs to a class of medications known as potassium sparing diuretics. Its main purpose when used in conjunction with another diuretic is to help maintain electrolyte balance. Due to its antiestrogen effects spironolactone at high doses may decrease sperm count. Colchicine is a drug used in acute attacks of gout.
Colchicine acts by decreasing inflammation in an acute attack.
Aside from anti-inflammatory actions, colchicine also has cytotoxic effects. Colchicine blocks cell division by binding to structures called mitotic spindles, that are necessary for cell division to occur. Colchicines cytotoxic effects may lead to decreased sperm production. Sulfasalazine is a medication used in the treatment of ulcerative colitis and Crohns Disease. Sulfasalazine belongs to a class of medications known as sulfa drugs, used mostly for their antibiotic actions.