Run Disk First Aid. Try running application without other applications also running. Go into Get Info and raise the memory allotted to it. Trash Prefs for that application. Check system with anti-virus software.
Application fails to launch.
Restart with minimum extensions and try it. Delete and reinstall the application. Trash the application, being sure to get the prefs and any Control panels and Extensions. Reboot the computer with extensions off except for the Apple CD Driver if needed. Reinstall the application.