Experiments have proved that analgesics containing more than one drug are more likely to damage kidneys. Many people in Australia have kidney disease as a result of taking large doses of analgesics containing two or more ingredients. Currently only a few types of analgesics contain more than one drug. It is safer to use those that contain one drug only, and these should be used strictly according to the instructions on the bottle or packet. Analgesics containing aspirin can cause internal bleeding and may lead to stomach ulcers, if you take them regularly or in large doses.
All analgesics can damage kidneys if they are taken in large doses for a long time.
Always drink plenty of milk or water with analgesics. A full glass with each dose is best. Soluble aspirin tablets that dissolve in water are often recommended, particularly for children. They can be a good choice, and they are easy to take. But soluble aspirin tablets are not absolutely safe just because they dissolve in water and cannot be seen.