M.D. My laboratory focuses on biochemical, biophysical and molecular signal transduction mechanisms initiated by plasma membrane receptors in mammalian cells.
Current emphasis is on neuropeptides and calciotropic hormones.
Wild type and mutant receptors and transducing molecules are expressed in animal and human cells and in Xenopus oocytes. Responses are measured at the nucleic acid and protein levels and are related to function using cell biological and electrophysiological techniques. Click here for a more detailed research description.