One of our patients recently died from an undiagnosed ulcer while taking an anti-inflammatory medication. It has also been demonstrated that anti-inflammatory drugs may worsen cartilage damage causing further progression of the joint damage. Narcotic pain relievers are indicated for short term use, however in a patient with chronic pain, their use becomes more habitual. In the 20 years that I have been a pharmacist, I have seen more people addicted to codeine and it's derivatives than any other compound. All of these people suffered from chronic pain.
Corticosteroids are also anti-inflammatory drugs and are meant for short term use.
Long term treatment with corticosteroids leads to adrenal suppression and a decrease in bone density. One capsule three times daily can be a suitable alternative for many patients. The study was completed over a 3 year term and strictly complied with double blind scientific protocol. The medicated group had significantly improved symptoms and possibly improved cartilage development, determined by X-Ray analysis. This is the first scientific study to provide an alternative treatment that can modify the outcome of Osteoarthritis rather than just treat symptoms.