The florid ductular proliferation appears to be associated with the underlying liver injury and does not appear to represent a neoplasm. The liver needle core biopsy shows distortion by nodules surrounded by extensive fibrosis. The fibrous septae show mild mixed inflammation consisting of neutrophils, lymphocytes, rare histiocytes and rare plasma cells. The septae show extensive cholangiolar proliferation. There is mild interface activity.
Cholestasis is present near the limiting plate.
The lobules show pericellular fibrosis and scattered neutrophils. These neutrophils in some areas surround swollen degenerating hepatocytes. Some of the swollen hepatocytes show Mallory's hyaline. Some areas suggestive of scar like fibrosis are seen within the fibrous septae. All rights reserved.