In any APOE testing, either diagnostic or predictive, extreme care should be taken to avoid damaging psychological and social consequences to individuals and their families. The Stanford statement goes further than the others in its opposition to APOE testing for diagnostic purposes. The genetics of Alzheimer's disease. BMJ 317, 361-362 . An editorial about the A2M mutation and Alzheimer's risk.
Caution is recommended unless the association is confirmed in population studies .
The Alzheimer's gene puzzle. Science 280, 1002. Mayeux, R. et al. Utility of the apolipoprotein E genotype in the diagnosis of Alzheimer's disease. Alzheimer disease research comes of age.