Antimony trisulfide is used in the production of explosives, pigments, antimony salts and ruby glass. Occupational exposure may occur during these processes and also during the mining, processing and smelting of ores containing antimony trisulfide. No lung tumour was seen in male rats. No lung tumour was seen in males. The available data were inconclusive.
Antimony trioxide causes pneumoconiosis in humans.
One study of women exposed to dusts containing metallic antimony, antimony trioxide and antimony pentasulfide suggested that they may have had an excess incidence of premature births and spontaneous abortions and that their children's growth may have been retarded. Antimony trioxide induced DNA damage in bacteria. There is inadequate evidence for the carcinogenicity of antimony trioxide and antimony trisulfide in humans. There is sufficient evidence for the carcinogenicity of antimony trioxide in experimental animals. There is limited evidence for the carcinogenicity of antimony trisulfide in experimental animals.