Some are not registered for use in certain states. The source of Pyrethrum and Pyrethrins is powdered, dried flower heads of the pyrethrum daisy that is grown mostly in Kenya. The mode of action is disruption of nerve function. The pyrethrums cause rapid knock-down and paralysis. Only a few cases of human poisoning have been reported.
Cats are highly susceptible to pyrethrums.
Exposure to high doses may cause vomiting, diarrhea, headaches and allergic reactions. It is used as a contact poison with no residual. Rotenone is produced from the roots of Lonchocarpus sp. The mode of action is the inhibition of cellular respiration in nerve and muscle cells causing rapid cessation of feeding. It is degraded rapidly in the liver.