The Project's algorithms provide a base of knowledge for determination of what is best for a particular patient. They are not a set of steps to memorize and use without deviation. Other algorithms are ready to be computerized. The software to present the algorithms has been in development over the last nine years. Other decision support information available at the site includes medication dosing strategies, side effect management, a program which offers detailed information about cytochrome P450 drug interactions that might occur when multiple drugs are prescribed, comparative costs of different medications, and algorithms for assessing and managing treatment compliance issues.
All information is extensively referenced.
Each algorithm program offers a virtual consultation by asking the clinician questions about the patient. The reasoning behind the sequence of questions is explained at each step. The questions conclude with recommendations which are discussed and referenced, and the merits and problems associated with alternatives to the first-line choices are reviewed. Questions and recommendations are accompanied by clinical confidence ratings which indicate the strength of scientific support for them. Updates of the programs can be distributed over the Web.