Many properties have inspections right up front. The seller will have them readily available in the house for a buyer to review. This is very helpful, so you know the condition of the property up front, but never be afraid to ask questions. There is a lot of information to take in, so don't be shy. Your realtor does not know what you do and don't know.
Constant communication is of paramount importance.
Get help with the details. Believe me there are many. You might overlook property flaws in the excitement of buying a home or in the rush to lock in a good interest rate. Finally, purchase a home warranty policy. It is a great insurance policy for peace of mind.