Special building materials have been used to ensure all surfaces and service penetrations, such as electrical and plumbing, are sealed.
Air flow is controlled by use of negative pressure zones to ensure air is directed into the lab.
This is accomplished by dampers and interlocking bioseal doors. All work with infectious agents is done using a special biosafety cabinet, which provides negative pressure to the room. Scientists in the Biosafety Level 4 lab wear protective, positive pressure suits, with filtered breathing lines. This ensures a protected air supply and that in the event that a suit were to be punctured, the flow of air would redirect any disease agent out of the suit and into the room. All air, water and waste is treated in some way before leaving the laboratory.