Marfan s syndrome is a genetic disorder of the connective tissues. It is the result of a mutated gene. Since all germane relatives have genes in common, more than one family member may be affected. In some rare cases a spontaneous mutation has occurred. Dr. Marfan s name became synonymous with patients affected by this same syndrome.
Connective tissue acts as the support system of individual organs as well as the entire human body.
Marfan s syndrome may affect the skeletal system, ocular system, cardiovascular and pulmonary systems in varying degrees. A high palette and over crowding of the teeth are usual occurrences for individuals with Marfan s syndrome. The most common effect on the ocular system is myopia or nearsightedness. Nearly one half of the patients with Marfan s will have dislocated lens. This dislocation may be mild or severe.