A systemic, chronic syndrome characterized by non-specific inflammation of the peripheral joints and related structures.
Crippling deformities are the end result.
The cause is unknown. A hypochromic, normocytic anemia is found in most of these cases with a corresponding very low hemoglobin. A superimposed iron deficiency is also common. The white cell count may be elevated and there is frequently an enlargement of the spleen. It also aids in detoxification.