Anyone who learned to read in the West reads from left to right, then top to bottom. This means that you, as an author, should put the most-important information at the top left and should put suggestions as to where the user might want to go next at the bottom right. This sounds so simple that you might wonder why so few designers use it. The reason is that designers tend to put at the top left what they, themselves, are most interested in, or merely what they think of first. This is often a vary different eye.
Colors evoke different emotions.
In fact, many colors that are socially acceptable to the Western eye are more or less obscene to other eyes. Some cultures frown on the open spaces and simplicity that are prevalent in today's Western design. Many other cultures prefer a busy-looking design that has lots of bright colors, strong textures, and stylish letter forms. Unfortunately, we are poorly equipped to supply design guidelines for other countries. It is incumbent on you to know your audience and what is appropriate for your audience.