This standard dosage applies to adults, children and infants. A second course of treatment should be given to those patients who are still infected three to four weeks after the first course. In worm-eradication campaigns the standard course should be administered every quarter during the first year. When gastro-intestinal transit time is accelerated, eg. Push the plastic skrew cap down While pressing down, turn the cap counter clockwise.
Agranulocytosis can occur.
In cases of massive infestation expulsion of worms may occasionally cause transient symptoms such as abdominal pain and diarrhoea. Adverse reactions Hypersensitivity reactions such as exanthema, rash, urticaria and angio-oedema have been observed. Drug interactions Concomitant treatment with cimetidine may inhibit the metabolism of the mebendazole in the liver, resulting in increased plasma concentrations of the drug especially during prolonged treatment. In the latter case, determination of plasma concentrations is recommended in order to allow dose adjustments. In the event of accidental overdosage, abdominal cramps, nausea, vomiting and diarrhoea may occur.