Royal Jelly has been implicated in at least one asthma death. There's also been one case of haemorrhagic colitis associated with royal jelly ingestion. Royal jelly produces typical IgE-mediated hypersensitivity reactions unlike the reaction produced by bee toxin in sensitive individuals. To many royal jelly web sites' credit, most advise that asthmatics and people with allergies not to take the product. Although, even people without previously known allergies need to be aware of the signs and symptoms of an allergic reaction, and what to do if one occurs.
Allergies can develop in anyone.
Symptoms can begin within a few minutes to several hours after ingesting the product. The typical reaction is runny nose, itching and puffy eyes, skin reactions of rash or hives, wheezing, and shortness of breath. First time reactions can be frightening and immediate medical attention is required. Panic can make things worse. Known asthmatics should take their Rescue Medication and seek medical attention immediately.