Any worsening of kidney disease that occurs during pregnancy is transient in many women with mild kidney disease. In more severe cases, the worsening is more likely to be permanent. Autonomic neuropathy , or nerve damage to the internal organs, can complicate the management of diabetes in pregnancy. This is sometimes manifested by gastroparesis, which disrupts the digestion of food and requires careful treatment before pregnancy. Peripheral neuropathy is nerve damage, including disorders such as carpal tunnel syndrome, and may be worsened in women who are pregnant.
Cardiovascular disease can be dangerous during pregnancy if untreated.
Your doctor will want to see your exercise tolerance in the normal range to maximize the probability that your heart can tolerate the increased demands of pregnancy. Women who have had angioplasty or other coronary revascularization procedures have had successful pregnancies. Even more important is to maintain them at that level for at least the critical first three months of pregnancy. That is when the baby is developing rapidly and the time during which congenital malformations can occur if glucose levels are high. Above that, however, the incidence rises.