Codeine 60 mg orally is not an effective analgesic for postoperative pain.
Codeine is an opium alkaloid, with activity similar to, but weaker than morphine.
It is also widely available in combination with aspirin or paracetamol. Oral tramadol versus placebo, codeine and combination analgesics. Baseline pain was moderate to severe. Dental trials and postsurgical trials were also analysed separately to establish whether this had an effect on the NNTs and relative benefits of the drug conditions. The meta-analysis was carried out on eight postsurgical pain trials and nine dental extraction trials.