Immediate hypersensitivity was first reported in 1979, with only sporadic cases until 1990. In the late 1980s, there were 450 incidents of anaphylactic reactions from the latex cuff used on barium enema catheters that resulted in 15 deaths. The allergic response. Latex contains hundreds of proteins, natural rubber products, and enzymes that are involved in the biosynthesis of robber molecules. Protein fractions in latex are responsible for anaphylaxis, a reaction that can lead to death.
Allergic reactions involve the immune system.
During an allergic reaction, an antigen interacts with antibodies and produces a massive release of histamine at a local or whole body level. In latex reactions, the latex protein is the antigen. Types of reactions. Types of reactions to latex products includes dermatitis, contact dermatitis, and immediate hypersensitivity resulting in anaphylaxis. Dermatitis is a chemical irritation, however, and is not a true allergic response.