An inherited disease that belongs to a group of diseases called mucopolysaccharidoses. Causes and Risks Hurler syndrome is inherited as an autosomal recessive trait. Newborn infants with this defect appear normal at birth but, by the end of the first year, signs of impending problems begin to develop. The children slowly develop coarse thick features, prominent dark eyebrows, cloudy corneas, progressive stiffness, and obvious mental retardation . The disease damages many organs including the heart and heart valves.
Death occurs in the early teens, often from the associated heart disease .
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