Seizures are a frequent presenting symptom and may commence up to 7 or 8 days following cessation of the sedative-hypnotic. In severe cases, treatment of convulsions takes priority. General symptomatic and supportive care is very important and includes reassurance and provision of a calm environment. Once the patient has been stabilised, gradual drug withdrawal can be undertaken. In severe cases, death may occur in the absence of adequate treatment.
Careful observation is required during that period.
Adequate nutritional and fluid intake should be ensured. Appropriate social and psychological support is an essential component of medical management.