Slide 2 Liver lobule outlined by blue connective tissue septa.
Central vein is in the center.
The irregular-shaped empty spaces with endothelial linings are lymphatics. Slide 5 Diagram of arrangement of lobule. A portal triad is at the left. Blood in the branches of the hepatic artery and portal vein enters the sinusoids, between the cords of liver cells, and courses toward the central vein, which is a tributary of the hepatic vein. Bile flows in the opposite direction, from the center out, toward the tributaries of the bile duct.