A women who has too much estrogen has estrogen receptors that are desensitized or down regulated to estrogen. Her body tries to compensate for the large estrogen load by becoming less sensitive to estrogen. Then, she tries to use natural progesterone without first getting rid of the estrogens in the environment. Natural progesterone resensitizes her estrogen receptors to normal sensitivity. She begins to get worse.
Breasts become more sore.
Bloating is worse. Failure is almost guaranteed when estrogens and xenoestrogens are not cut out of the patient's environment. In rare cases, the patient may change his lifestyle and take Natural Progesterone and still get worse. Xenoestrogens may stored in the body for decades. Sauna treatment may be used to get rid of these stored xenoestrogens.