Seriousness depends on where the virus invades. Plantar warts on the bottom of the foot are painful because the inflammatory response can make walking difficult. Sometimes scar tissue must be cut out surgically. Genital HPV sometimes makes little bumps and other times a giant cauliflower like lesion called condylomata acuminata . This disruption of the genes controlling apoptosis can cause cervical and penile cancer .
Cervical cancer is a sexually transmitted disease.
Basically, if you are not sexually active you will not get cervical cancer. Sometimes the immune system can make a finally effective 3rd line immune response.