The purpose of this request for applications is to develop mouse models for studying the biological function of genetic variants of DNA repair and cell cycle control genes found in the human population. Mutant mice, protocols, assays, assessment criteria, and other materials and information generated in projects funded under this program will be made available to the wider biomedical community for further investigation or application. Letters of intent are due 12 May 2000 and applications are due 20 July 2000. This solicitation will lead to grant awards that establish pilot projects in a limited number of eligible cities. The pilot projects will emphasize using advanced and innovative technologies to monitor environmental conditions as well as provide and communicate environmental information to citizens.
Awards are subject to the availability of funds.
The closing date is 10 April 2000. Research on underlying metabolic, genetic, epidemiologic, sociocultural, and behavioral mechanisms that contribute to racial and ethnic differences in the etiology of type 2 diabetes mellitus is sought by the National Institute of Diabetes and Digestive and Kidney Diseases. Similar funding is anticipated for FY 2001. Applicants must use Application Form 398, which has annual due dates of February 1, June 1, and October 1. Letters of intent are requested by 30 June 2000 for proposals that are due 10 August 2000.