100M is still not public. Tissue damage during a 100M run increases dangerously the risk of single or multiple organ failures like cardiovascular, pulmonary failure or renal shutdown etc., depending on our state of health when we enter such an event. I would like to contribute to the understanding of the mechanisms and possible dangers of ultra races. Damage to tissue in our body is called trauma. Hypoxemia for example can be the initial trauma cause, making tissue all the more sensitive to free radicals.
All factors potentially lead to shock, which further increases trauma in a vicious circle.
Antioxidants like Vit. E and C do help during endurance aerobic workouts, but trauma will occur in any case at least to a certain extent. Tissue trauma happens in all organ systems of our body. It results in membrane breakdown of cells. In a 100M event, when we run in good shape from the start to the finish, trauma at least occurs in muscles and capillaries.