The National Toxicology Program accepted responsibility for conducting trials on carcinogenicity and in June 1993 released results showing that feeding mice Ritalin induced liver tumors including very rare and highly malignant cancers. These results were found at levels close to those routinely prescribed for children. More studies are being planned for testing Ritalin, but the evidence is strong. Animal tests are very good predictors of human health effects. The response of the FDA and Ciba-Geigy to the cancer test results were not adequately protective of child's health.
Animal tests are very reliable predictors of human effects.
Of the 23 known human carcinogens, all were identified as carcinogens in animals first, sometimes decades earlier. It is disconcerting that the FDA is not making a move to ban or limit the use of this drug. While Ritalin is the most commonly used drug for attention deficit disorders, now prescribed to 60 to 90 percent of American children with such disorders, there are Pharmacological alternatives. There are also non-drug therapies for ADHD and related mental health problems. For example, behavior modification therapy has been particularly effective with ADHD cases.