Infants may be contagious. Immunize children and nonpregnant women of childbearing age. Immune globulin given to mother does not prevent prenatal infection. High probability that infected mother will transmit the disease. Treponemes cross placenta in all trimesters.
Clinical picture can be benign to fatal.
Diagnosis and treatment. Titer should revert to negative at 6 months. HIV testing should be considered. See treatment of newborn in previous section and Chapter 16 . Supportive measures for enterovirus infection.