Laboratory testing is usually not necessary as part of the ED evaluation. However, leukocytosis and eosinophilia may be observed in severe cases. However, if contact dermatitis is being considered, patch testing for other allergens might be considered. If the toxin can be removed before this occurs, reaction can be avoided. Although multiple products are marketed for skin decontamination, they are only slightly more efficacious than soap and water.
Copious water is recommended, because soaps can spread the urushiol oil around the skin.
It is important to instruct patients to clean their clothes and any other objects that might have been in contact with the oils. Topical preparations for symptomatic relief are the standard care for poison ivy exposure. Domeboro, calamine, oatmeal baths, and Burrow solution all have been recommended. To prevent ground oatmeal from caking in pipes, it can be placed in a tied sock before being dropped in the bathtub. Oral antihistamines can be of some benefit for the relief of pruritus, especially in severe cases with urticarial lesions accompanying the bullae.