Gout occurs when the buildup of uric acid causes inflammation in the knee or foot. Alcohol can reduce the body's ability to get rid of uric acid. Drinking too much alcohol increases the risk of cancer of the liver, pancreas, mouth, tongue, pharynx, larynx, and esophagus. Besides liver cancer, alcohol may cause fatty liver, hepatitis, cirrhosis, and other liver disease. Nervous system problems.
Alcohol can create a deficiency of thiamine, which can disrupt the functioning of the nerves.
Heart and circulatory problems. Heart failure can be caused by a lack of thiamine. Other physical problems. People who drink heavily can have changes in moods and emotions, causing them to become angry and irritable. Also, they can have personality changes, such as becoming suspicious, jealous, or possessive.