Patients, however, do not usually present with jaundice or other symptoms. Hepatitis does not linger after virus is cleared 2. CMV major cause of hepatitis in immunocompromised patients 3. Herpes problem in immunocompromised patients . May be fulminate 4.
Blood becomes static within central veins and necrosis insues .
Ethanol depletes glutathione , reducing the dose needed for toxicity. The toxic reaction is a delayed one, so the dose must be compared with time since ingestion and apparent symptoms. A patient may be smiling three hours after the dose, but 24 hours later may have lost their liver. Heterozygotes with different mutations on each allele are the most common presenters of this disease. Without functioning copper transporters, ceruloplasm accumulates in the liver where it exerts its toxic effects.