As anyone can observe from their own injuries, blood will clot within minutes if the proper conditions are present. In some disease states, clotting occurs when it shouldn't. Blood clots which form in an abnormal time or location can be dangerous. These clots can break loose from their attachment and migrate into other body organs, causing damage. Large clots can obstruct blood flow.
Anticoagulants often help reduce the chance of sudden graft closure.
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