However, more studies with larger numbers of study participants in well-controlled clinical trials are needed to show a difference between rigorous exercise and diet modifications. Further studies are needed. However, this was a small number of patients, and more information needs to be collected. A large-scale trial is scheduled to begin later this year. Osteopenia was found in patients who presented with lipodystrophy and was reported in patients not receiving any medication treatments, but appeared more common in those patients taking medication.
Additional information is needed before a determination can be made as to the cause.
IL-2 is showing promise to potentate the replication of CD4 cell counts. Several presentations looked at the administration of IL-2 in patients who have viral suppression on currently stable ART therapy for a minimum of four months. When compared to a control, patients receiving IL-2 had a significant increase in CD4 with viral loads that remained undetectable. Changing medication to a maintenance therapy may require fewer pills and less complex regimens and may offer an improvement in dosing. Again, adherence is extremely important in maintaining durability of any medication regimen.