Cytology Contain residual ribonucleoprotein particles which impart a bluish hue to the cell on Romanowsky staining. A supravital stain such as methylene blue is needed to definitively identify the ribosomal remnants in reticulocytes. Cytology The mature neutrophil measures approximately 12-15 m diameter in a smear. It is characterized by a prominent nucleus segmented into 2-5 lobes joined by extremely fine nuclear strands. Most numerous of the white blood cells.
Cytoplasm contains two major types of granules.
They are most commonly found in promyelocyte stage of neutrophilic precursors. They are primary lysosomes which contain myeloperoxidase and acid hydrolases characteristic of lysosomes. Functions First line of defense against microorganisms, especially bacteria. Killing and digestion occur. Activated oxygen species also form and kill microorganisms.