Amphiphatic layer structure in the crystal.
Colored balls represent the solvated water molecules and the arrows show the water-layers.
In the asymmetric unit, two peptide molecules were existed with solvent molecules, and total molecular weight were over 3000 Dalton. The crystal structure including solvent molecules was finally determined at 0.80 A resolution by using synchrotron radiation. About thirteen hydrated waters were found at disordered nineteen sites, and they were located on a certain region to avoid the contacts with aliphatic side chains of peptolide in the crystal. The spatial dispositions of solvent molecules and peptides subsequently created the amphipathic layer structure. Acta Crystallogr., Sect.