These are classified into distinct homeomorphic protein superfamilies. Please note that the homology domain sequence is aligned and non-homologous sequences are excluded. SCOP SCOP is a structural classification of proteins maintained by Drs Alexey G. Murzin, Bartlett G. Ailey, Steven E. Brenner, Tim J.P. Hubbard, and Cyrus Chothia at the MRC Laboratory of Molecular Biology and Centre for Protein Engineering, Cambridge. Proteins are classified into protein domains, families, superfamilies, folds and classes. Individual domains of multidomain proteins may be classified separately.
Annotation is minimal.
PIR Database PIR is the oldest protein sequence database, originating from the Atlas of Protein Sequence and Structure books of Margaret Dayhoff. Because of the way sequences are filed and annotated, any one sequence can acquire several accession numbers, and redundancy is only removed at the highest level of filing. The links are to the SRS server at the EBI at Hinxton, Cambridge. In Man database is a collection of data on human genetics. The OMIM database is maintained by Dr Victor A. McKusick and colleagues from the Johns Hopkins University.