To avoid finding yourself in the vulnerable position of being stranded, make sure your car is in tip-top shape before you set out. Carry an emergency roadside kit containing flares, a flashlight, first aid kit, blanket, etc.
Cellular phones offer great safety advantages, too.
Don't drive in deserted areas at night and avoid poorly lit areas. Keep your car's windows closed and doors locked while stopped in traffic. Leave ample room between your car and the car in front of you. Don't stop and offer assistance at accidents. They may be staged by criminals.