Thiamin, acts as a coenzyme in body metabolism.
Deficiency leads to beriberi, a disease of the heart and nervous system.
Thiamin is especially important as a supplement for persons with serious liver conditions. Riboflavin, essential for the reactions of coenzymes. Deficiency causes inflammation of the lining of the mouth and skin. Deficiency causes inflammation of the skin, vagina, rectum and mouth, as well as mental slowing. Niacin is used in the treatment of cholesterol disorders.