These rejecters of the word of God were in the Christian Church and were professing the Truth but denying the true Christ who bought them. They were actually making war with Christ and believing in a false or Anti-Christ. And the kingdom and dominion, and the greatness of the kingdom under the whole heaven, shall be given to the people of the saints of the most High, whose kingdom is an everlasting kingdom, and all dominions shall serve and obey Him. The Antichrist and those who follow him make war against the Everlasting Covenant of Christ and think they can change the covenant which God has made with His people. Satan wars against God with a two edged sword, legalism and antinomianism.
All false religion falls into either Legalism or Antinomianism.
Legalism is to earn justification and acceptance before God by ones obedience and good works. Antinomianism is to profess to be justified while willfully disregarding God's holy Law or any portion thereof. He shall separate the precious wheat from the tares in the judgment. He knows already those who are trusting in the blood of Christ and who have sent their sins on beforehand to judgment. But that all the universe and the angels may see the justice of God, God tests His people to reveal them who love Him and them who make a false profession.