It is certainly the most comprehensive of all the commandments. Perhaps it appears last because the sin it prohibits, covetousness, is the most treacherous of all. We need victory at this point more than any other. Covetousness makes people greedy and causes them to steal. Covetousness drives people to sacrifice the lives of others, even to kill, for their own ends.
Covetousness gives rise to that unbridled lust which plunges individuals into adultery.
Covetousness endangers mutual trust and causes people to lie or to bear false witness about themselves and others in order to gain money, power, prestige or praise. So the tenth commandment is comprehensive. It is also difficult to explain. Our desire for food makes us hungry and we eat. Other legitimate desires are to conform to the rules of social etiquette and to get along well with others.