Main Research interests Membrane transport, Physiology of the malaria parasite, Cell volume regulation. Malaria is an infectious disease caused by a unicellular microorganism which, during the course of its lifecycle, invades the red blood cells of its vertebrate host. A detailed knowledge of these pathways will provide the basis for new antimalarial chemotherapeutic strategies as well as an understanding of mechanisms of antimalarial drug resistance. Mechanisms of cell volume control.
Cells exert a tight control over their size.
This phenomenon is under investigation in a number of different cell-types, ranging from human cancer cells to parasitic protozoa. Functional properties and physiological roles of organic solute channels. Transport and metabolism of the essential vitamin pantothenic acid in human erythrocytes infected with the malaria parasite Plasmodium falciparum. Increased permeability of the malaria-infected erythrocyte to organic cations, Biochim. Transport of lactate and pyruvate in the intraerythrocytic malaria parasite, Plasmodium falciparum.