Intelligence varies from normal to mild learning disability. Growth rate usually slows at 4-5 years. Early adolescent development usually occurs.
Adults are usually within normal height parameters.
Inheritance patterns Most cases are sporadic mutations. Once established inheritance is autosomal dominant. Weaver syndrome inheritance probably has some pattern of inheritance though this has not been fully determined. Pre-natal diagnosis Macrocephaly, large hands, long arms and excessive growth are detectable using ultrasound scanning. Genetic counselling is available for affected families.