Many enter into the blood stream via indwelling catheter. Disctitis following bowel surgery has been reported. Meningitis is common in children, whereas micro or macroabcess in adults. Serological tests are not reliable. Survival is rare in patients with abscess formation.
Death is usually a result of multiorgan failure.
Less common and spinal involvement is almost unknown. CNS involvement is almost unknown. Clinical presentation is abscess or mass lesion, meningitis is almost unseen. Vasculitis leading on to thrombosis and mycotic aneurysms in common involving proximal larger arteries. CSF findings are nonspecific.