However anyone can develop physical dependence on opioids, whether or not they have an addictive tendency. In some people, the daily use of an opioid analgesic for as little as seven to ten days after surgery, can result in physical dependence and withdrawal symptoms, if they suddenly stop their opioid. All cancer patients on long-term opioids are probably physically dependent. Research is currently investigating where in the brain this process of physical dependence occurs. One day we hope to be able to manage this side effect, so that it will not be a limitation for opioid therapy.
Addiction is something quite different.
Somebody who is addicted uses the opioid for a reason other than pain. They may be using it to change their mood or to get a high. Some describe being energized by taking opioids. So, the reason they take it differs from the reason it was prescribed by the doctor. By using opioids in this way, they usually begin to experience consequences in their life.