A single high exposure can permanently damage the lungs. Acute exposure to chloroform can irritate and burn the skin, eyes, nose, and throat, and cause dizziness, lightheadedness, headache, confusion, and irregular heartbeat which may lead to death. Chloroform is a probable carcinogen and is suspected of causing birth defects. Chronic chloroform exposure can damage the skin, liver, kidneys, and nervous system. It is used to make silicones.
Direct contact can severely irritate and burn the skin and eyes.
It is used to make plastics, resins, and glycerin. Acute exposure to epichlorohydrin vapor irritates the eyes, nose, bronchial tubes, and lungs. High levels can chemically burn the lungs or cause dangerous fluid build-up, which may lead to death. Eye contact may cause permanent damage, and skin contact can cause painful blistering which may be delayed in onset for minutes or hours. Chronic exposure can damage the kidneys, liver, and lungs.