Antibodies raised against such antigen may have antitumor activity. To date, MAb by itself is not found to produce significant anticancer effects. However, it could be used to deliver conjugated cytotoxic agents such as drugs, toxins, and radionuclides to the tumors. This conjugate tends to inhibit proliferation of breast cancer cell lines better than the unconjugated MAb. This ovarian failure can be prevented by changing certain steps in the complex apoptotic pathway.
Active radicals produced by aerobic metabolism can cause damage to living cells.
Defense systems exist in cells can eliminate these radicals. Superoxide dismutases, special enzyme systems are part of this mechanism. Since cancer cells are comparatively active in aerobic metabolism and have low levels of superoxide dismutases, inhibition of these enzymes can kill the cancer cells. 2-Methoxyestradiol, an estrogen derivative is found to selectively kill cancer cells by inhibiting superoxide dismutase. State of the Art Dysplasia of the hematopoietic system has become, in the last two decades, an issue of growing frequency and importance.