Urinalysis disclosed numerous polymorphonuclear leukocytes, some lymphocytes and occasional red blood cells in the centrifuged sediment. The gross specimen was a lobulated nodular firm mass, weighing 75 Gm, surrounded by a poorly defined roughened capsule. Note how glandular architecture is maintained, but there is an increased number of glands showing infolding of epithelium. Tall columnar cells forming papillary infolding due to cell proliferation. Nuclei are small and uniform in shape and basally oriented.
Basal cells are also present.
Lab manual questions 1. Nodular hyperplasia of the prostate may be primarily due to fibromuscular stromal hypertrophy and hyperplasia or to glandular proliferation or to a mixture of both. In BPH, not infrequently, aggregates of lymphocytes are found within the stroma, probably related to senile atrophic death of cells. Unless the patient undergoes a total prostatectomy, a considerable amount of prostatic tissue remains after the nodules are removed surgically so that, at a later date, it is entirely possible for recurrent nodules to develop. This patient has numerous PMN's in his urine.