Each Ab is the product of a different gene. 2.Two-Gene Model V and C segments are encoded by different genes with many V and few C genes.
Any L chain can combine with any H chain.
There are few genes for the V region which undergo many, many mutations, while the C region does not mutate. During maturation of the B cells into Ab-producing cells, the fragments are brought together and the intervening material is removed. Any V gene can combine with any J gene. 6 J 2.C region of encoded by C gene. C gene codes for aa 11-214.