Violent reactions will occur if chloroform makes contact with strong caustics and chemically active metals such as aluminum, magnesium powder, sodium, or potassium. Synonyms for chloroform are methane trichloride and trichloromethane. Chloroform is a carcinogen. It is also believed to be a teratogen in animals, and possibly in humans. Other long-term health effects include damage to the liver, kidney, and nervous system, and drying and cracking of the skin.
Alcohol consumption can increase the liver damage caused by chloroform.
Immediately or shortly after exposure to chloroform, the heart may beat irregularly or stop. Exposure can also cause dizziness, lightheadedness, nausea, confusion, and headache. Contact with it can irritate skin, causing a rash or burning feeling. The liquid can cause severe eye burns. Exposure to the vapor can irritate the nose and throat.