Though it is the most used drug in the treatment of breast cancer, it stops working after a period of time in many patients. In animal studies, faslodex has been shown to work in tamoxifen-resistant tumors. The female hormone estrogen, crucial to the development of breast cancer, stimulates cells by binding to a protein called the estrogen receptor. Researchers are trying to learn as much as possible about the receptors to determine if they could be involved in the development of breast cancer or in hormonal resistance like that being studied in tamoxifen. Pre-malignant breast disease.
Breast cancer evolves through a series of stages.
Studies are under way to determine what genetic changes take place in the earliest stages, before the cancer has developed. If scientists can identify a genetic mutation in a patient before the development of breast cancer, that patient could be targeted for special prevention measures. All Rights Reserved.