Currently, research efforts are directed toward defining mechanisms that regulate and induce release of peptides from nerve terminals. In addition to analyzing the effects of peptides in the adult nervous system, the lab has established a strong collaboration with Dr. James S. King to analyze the effects of peptides during development of the cerebellum. In addition, collaborative efforts with Dr. Richard Burry are designed to analyze the cellular mechanisms by which peptides influence both synaptic plasticity and development. PAP and fluorescent techniques 2. Horsereadis Peroxidase, fluorescent microspheres 3.
Calcitonin gene related peptide modulates neuronal activity in the mammalian cerebellar cortex.
Peptide localization in the mouse inferior olive. The distribution of tyrosine hydroxylase-immunoreactive afferents to the cerebellum differs between species. Brainstem origin of corticotropin releasing factor afferents to the nucleus interpositus anterior of the cat. The site of origin of calcitonin gene related peptide-like immunoreactive afferents to the inferior olivary complex of the mouse.