Follow good personnel policies, such as regular evaluations and reviews, business meetings, informal discussions, etc. Project the best case scenario for your needs. Project the worst case scenario for your needs. Get a feel' for where reality will fall between the best and worst case scenarios. If your initial assessments are filled with problems you may need to restructure or redesign your business.
Design flaws become more pronounced as a business grows.
If the flaws are not corrected they can stunt growth or create severe financial strains. Determine how steady or flexible your needs are. If your needs are flexible be very careful about permanent staffing. Look at costs. Spreadsheets are great for what-if scenarios.