Pyelonephritis and interstitial nephritis Parts of the kidney are chronically inflamed due to infection or use of drugs. Polycystic kidney disease Hollow spaces in the kidney tissue displace healthy tissue and accumulates urine. This causes harm in the surrounding tissue as well.
Diabetes Can cause high blood pressure, heart disease, small blood vessel disease.
All of these side effects will destroy nephrons. Diabetes is the leading cause of ESRD in the United States. Most renal failure types are categorized as either acute or chronic . This type of failure is a sudden loss of renal function that may be reversible. Common causes of acute failure are illness, injury, or toxins.