Called the Ride for Life, it is conducted by patients who are battling an untreatable, incurable and fatal disease with only their courage and determination. This year, the patients will be taking a 160 mile ride from Long Island's Montauk Point Lighthouse to St. Patrick's Cathedral in Manhattan, from April 28 to May 5. Without a medical miracle, they will face almost certain death from total muscle paralysis. The patients are riding to raise funds for ALS research and to provide needed patients services. All of our board members and staff are volunteers and receive no money for their work.
All donations are tax deductible to the extent of the law.
The Hoyer lift is difficult for my Mom to use. I have a friend that has ALS and is deteriorating fast. We can use the knowledge to screen for drugs that block the cytotoxic interaction. In neuroblastoma cells cotransfected with huntingtin sequences containing extended polyglutamine segments and CBP, the two proteins did, indeed, collect into aggregates and CBP was redistributed away from its usual nuclear location, the authors report. CBP without its usual contingent of glutamines did not form aggregates with huntingtin.