Unfortunately a trial of a one year course of an antibiotic didn't have any effect on the amount of protein lost in the urine or on the degree of damage to the kidneys. There was a reduction in the amount of haematuria. There is therefore no advantage to taking antibiotics, unless the provoking infection is bad and needs treatment in its own right. Again, taking out the tonsils reduces haematuria if tonsillitis is the provoking infection, but it does not affect the long term kidney function. There is no evidence that tonsillectomy prevents IgA nephropathy or renal failure.
ACE inhibitors tend to reduce the amount of protein lost and protect the kidneys.
If this happens all patients will be considered for kidney transplantation and most go onto the waiting list. In general, patients with IgAN do well with transplantation, but there is some evidence that after time IgA may be deposited in the transplant kidney causing IgAN to recur. Even if it does, it usually takes ten to twenty years before the kidney fails completely. The IgA home page is a dedicated web site for people suffering from IgA nephropathy containing a lot of information, much of which is useful, but not all of it and containing some prejudices. It is important to remember that web-sites are not edited in the same way as books.