Most of these symptoms are nonspecific and may be similar to those caused by benign conditions such as infection or prostate enlargement. Pain and systemic symptoms are late manifestations of the disease. Pain and weight loss occur late in the disease. Return to the top of the page Leukemia Signs and Symptoms - Fatique, paleness, weight loss, repeated infections, bruising easily, and nosebleeds or other hemorrhages. In children, these signs can appear suddenly.
Chronic leukemia can progress slowly and with few symptoms.