Disease may extend to the adjacent fat lobules and the inflammation often extends up to the deep dermis. There is no septal fibrosis in chronic erythema nodosum. Otherwise, systemic medications such as potassium iodide or dapsone are utilized. Dermatology should be consulted to perform a skin biopsy. There are no specific requirements.
Activity is ad lib, taking care to avoid trauma to affected areas.
The factors that should be considered include the extent to which the disease disturbs the patient and the potential adverse effects of the medication. Iodine products - Treatment with intralesional steroids may be effective. Otherwise, systemic medications such as potassium iodide or dapsone are utilized. Most commonly used therapy for this condition. Works via potassium concentration in granulomas, which releases heparin and inhibits delayed-type hypersensitivity response.