Buerger's disease is primarily caused by using tobacco products. It occurs evenly in both men and women, and usually begins after the age of 30. Symptoms in the phenomenon may affect only one side of the body. The disease generally begins in the teens or early twenties. But it can occur at any time in the life.
Attacks normally affect both sides of the body equally.
Gradually the attacks will be more frequent and last longer. In later years, the hands will be slightly bluish all the time. The fingers become swollen. The skin turns pale, discolored, shiny, taut, and smooth. The nails become clubbed and deformed.