Consider a site map or other alternative view of your web site's contents. Don't rely on Flash, Java, or Javascript for primary navigation options. A few months ago I visited a site which had a large flash animation as its home page - but their coding did not work on my computer. Pretty front door, but no way in. Include a title for each page.
Accessibility is more basic.
Think about your potential users. Some people are color blind, so your page colors may make the text unreadable. It was enthusiastically attended by over 300 delegates from as far as Russia and the Republic of Georgia. There were more than sixty inspiring sessions ranging from developing appropriate electronic means to share specialist information to raising the social awareness of citizens to preserve historical buildings in Hong Kong. Participants were guided through a series of hands-on exercises from homepage design to content building.