Application fails to function properly. Either double check the manual or preferably observe it behaving in the manner you expect on another machine. Cancel any automatic login to servers when you computer boots. Log into any Servers needed through Chooser or Network Browser. If this works, then trash all items in the Servers folder in the System Folder and recreate them if needed.
Application fails to print.
Make sure that other applications can print. If they can't, then it's probably a system issue. Create a brand new file, from scratch, put something in it, and print. If it prints, then your program and printer basically work and its something about the file you're trying to print. Try printing other files.