There is no direct correlation between lead level and symptoms. Encephalopathy may be preceded by behavioral changes, vomiting, and abdominal pain. With encepholopathy, there is persistent vomiting, papilledema, seizures, ataxia, and coma. The effect of chronic lower levels on neurodevelopment are controversial, but there is significant concern to warrant intervention and treatment at lower levels. There is some evidence that lower levels may affect behavior, school performance, IQ, and hyperactivity.
Absorption is enhanced by iron deficiency.
Risk of Lead Exposure Lives in or regularly visit house built before 1960 with peeling paint chips Lives in or regularly visit house built before 1960 that has recently undergone renovation Sibling or playmate has recently been diagnosed with high lead level Family member who works or has a hobby with lead Live near an active lead smelter or battery burning recycling plant. It may be given orally. Binds with lead and is excreted through the kidneys. There is a rebound effectafter cessation of therapy. It may cause nausea and vomiting secondary to its smell.