The other relates to the deamination of amino groups in DNA bases. Both of these processes have important biological consequences. We proposed a new bonding model and established crucial links between theory and experiment. Current studies of diazonium ions focus on the mechanisms of their S N chemistry and studies of the diazonium ions of DNA bases. To address questions as to the consequences of alkylation on DNA and RNA structure and properties, our initial studies have focused on studies of base pairing.
Current research focuses on detailed analyses of the origins for non-synergetic bonding.
These azines are important to advancing crisscross reaction chemistry, that is, the tandem 1,3-dipolar cycloaddition of azines with dienophiles and they show promise as novel nonlinear optical materials. In particular, we have found that one of these azines is highly dipole parallel-aligned in the crystal and indeed the such a degree of ferroelectric alignment is unprecedented and was thought to be impossible to achieve. The lattice architecture of the prototype is now being studied in great detail in collaboration with mathematicians. The experimental approach to diphosphonium ions primarily focuses on the Lewis-acid assisted ionization of polar diphosphenes. Choy J. Chem.