Take single dose in evening with or without food. Take single dose in evening with or without food. Obtain transaminase levels at baseline, at 6 to 8 week intervals during first year, and then at 6 month intervals.
Alcoholism is a relative contraindication.
Rhabdomyolysis with renal failure has been reported. Possible interactions with spirolactone, cimetidine and ketoconazole that reduce cholesterol levels and may effect adrenal and sex hormone production with concurrent use. Increases pravastatin AUC and C max 1.7x and 2.5x, respectively. The Johns Hopkins University on behalf of its Division of Infectious Diseases and AIDS Service. All rights reserved.