Round to oval basophilic structures were noted in histiocytes.
Clinical overlap exists between the various forms.
Initial cutaneous lesions usually occur as erythematous papules, weeks to months after the bite of an infected sandfly. The papules may enlarge and form nodules, which frequently ulcerate. Histologically, an inflammatory cell infiltrate containing parasitized macrophages may be seen in cutaneous leishmaniasis. The histologic differential diagnoses includes rhinoscleroma, granuloma inguinale, histoplasmosis, tuberculosis, and leprosy. Histologic Diagnosis of Inflammatory Skin Diseases.