The heart is enlarged due, in large measure, to accumulation of fluid in the pericardial sac. Patients generally note constipation , which may be severe. Paresthesia of the hands and feet are common. The reflexes may be very helpful diagnostically because of the brisk contraction and the slow relaxation time. Hypothermia is commonly noted if the temperature is measured rectally.
Anemia is often present.
A variety of thyroid hormone preparations are available for replacement therapy . This condition is characterized by an increased activity of the thyroid gland . Many symptoms and signs are associated with hyperthyroidism . The diagnosis of hyperthyroidism is usually straightforward and depends on a careful clinical history and physical examination , a high index of suspicion and routine hormone determinations . A number of approaches are utilized for the treatment of hyperthyroidism , for instance, the administration of iodine , radioactive iodine, certain antithyroid agents and surgery.