Click on title to view entire article. Sleep Disturbance and Chronic Pain Sleep disturbance is a prevalent clinical complaint among persons with chronic pain conditions. In the past, sleep disturbance in the context of chronic pain has been attributed to the pain itself. However, evidence from animal models and human investigations indicates a more complex relationship between pain and sleep. The toxin is derived from the class of bacteria known as Clostridium and is in fact the same toxin which causes the disease of botulism when ingested or absorbed through a wound.
Botulism is characterized by acute onset of flaccid paralysis.
Because of its ability to block muscle tone, the toxin has been used to treat conditions such as painful muscle spasms, myofascial pain syndrome, spasmodic torticollis, cervical dystonia, and even low back pain. New Treatments in Osteoarthritis Arthritis is one of the most common and debilitating diseases affecting patients today. In this category, osteoarthritis is the most common. Current treatment includes both medical and surgical therapy. Although these modalities work for many patients, there are a significant number for whom more invasive treatment is necessary.