After in-depth homogeneity and stability tests were complete, the project team began to measure the precise levels of Tg in the material. This value would be relied upon by laboratories everywhere, so it was very important to get it right. The project partners worked closely to complete their own measurements accurately. Each of them would perform the measurement and then they compared results in technical meetings to see where minor improvements could be made to reduce the now small variance in results. Once this was achieved in 1993, the material became available to testing laboratories and manufacturers of Tg measurement kits around the world.
Biomedical chemists can now compare their results with other institutions.
The material allows their measurements to be traced to a reliable source. Without the development of this reference material, accurate diagnosis and follow-up treatment would be difficult. Undoubtedly, many errors would be made and patients may not get the required treatment until it is too late.