Hypertension reduces the elasticity of vessels allowing lipids to deposit in the form of atheromas, which in turn leads to thrombus formation and possible emboli formation. This impedes blood flow and leads to ischemic disease. Coronary heart disease is the leading cause of death in hypertensive patients. Ventricular hypertrophy occurs as a result of increased cardiac output in the face of systemic vascular resistance. Eventually, the heart is unable to maintain this constant output and the hypertrophied muscle outstrips its oxygen supply.
Cerebrovascular disease is a serious complication of hypertension.
Hypertension is the leading cause of stroke. Hypertension-mediated atherothrombotic lesions are the cause. Hypertension-induced arteriosclerosis may also result in atrophy of the renal glomeruli and tubules. This results in a malignant form of hypertension, and renal failure is also a frequent cause of death. Management Reducing morbidity and mortality is the main goal in hypertension management.