Similar to an average SSRI as far as incidence of weight gain and sexual side effects. Typical dose range is 75-225 mg per day, sometimes given at higher doses. It also blocks the elevated serotonin from the areas which would cause sexual side effects, anxiety, nausea and diarrhea, and most serotonin side effects. For this reason these side effects aren't seen more than placebo. Remeron has a very high incidence of increased appetite and sedation.
Constipation can be a concern as well.
Minimal drug interactions. Longer half-life may reduce withdrawal symptoms. Remeron is taken once per day. It works by turning on one beneficial receptor for serotonin, and not some serotonin receptors responsible for serotonin side effects. This works very well in a fraction of people.