Pathophysiology Central to the pathophysiology of preeclampsia is vasospasm accompanied by intravascular volume depletion. In the absence of this normal process the spiral arteries fail to dilate maximally and continue to be responsive to vasoactive substances. Prophylaxis Unfortunately, there is no proven prophylactic measure to prevent PIH short of avoiding pregnancy. Repeat labs prn severity of disease. Consider ANA and uric acid.
Blood pressure is taken in the sitting position.
Blood pressure readings in the left lateral position are not valid for diagnosis. 5mg IV should prompt invasive monitoring. For preterm give RDS and antibiotic prophylaxis. Administration of larger or more frequent doses may lead to fetal bradycardia. In Cunningham FG et al.