Prograf is manufactured from a fungus that grows in the soil. It works by blocking the function and growth of T-cells. It can be given both intravenously and orally. Common side effects of Prograf include elevation of blood pressure, damage to the kidneys and liver, nausea, diarrhea, headaches, gastrointestinal problems, tingling of hands and feet, and tremors. As with cyclosporine, measuring blood levels of Prograf is important to determine the most beneficial dose.
All immunosuppressants have side effects and potential complications.
It is more likely that the combination of drugs contributes to the cause, not any specific immunosuppressant. However, cyclosporine often varies from one patient to another in the extent and timing of absorption from the intestinal tract, as well as how quickly it s used and eliminated by the body. Too much in the bloodstream might cause side effects, while too little might result in organ rejection. To determine the correct dose of cyclosporine for a particular patient, doctors look at several things including evidence of rejection, drug-related side effects, particularly renal function and the concentration of cyclosporine in the blood. The cyclosporine trough concentration, however, doesn t provide enough information about how the drug is actually being used by the body.