The result is a low platelet count that is artifactual, but this should be recognized as platelet clumps will be seen in a peripheral blood smear. EDTA-dependent pseudothrombocytopenia has been recognized in horses, but is a rare occurrence. Note that clotting of the sample will totally invalidate the platelet count. Platelet number can be determined in several ways. Before estimating platelet counts from a blood smear, the feathered edge of the smear should be examined thoroughly for platelet clumps.
Cats have notoriously reactive platelets, which clump readily on sample collection.
Therefore, obtaining a platelet count can be difficult in a cat. Therefore, if there are more than 10 to 15 platelets per field on average, the platelet count is within or above the reference range.