The Johns Hopkins researchers, under the direction of Dr. Bert Vogelstein, found that two cancer cell-lines contained mutations in a gene known as hBUB1, the human version of a yeast gene, BUB1, which checks chromosome separation in yeast. The Johns Hopkins research team, representing the Oncology Center, Howard Hughes Medical Institute, and the School of Medicine, also found evidence that defects in other mitotic checkpoint genes contribute to cancers, although this remains to be proven. If this is eventually proven, then the results will lead to understanding of how different tumors are affected by chemotherapy. And that discovery may lead to better selection of treatments for different types of tumors. This would be a major breakthrough considering that cancer remains one to the major causes of death among senior adults.
AD is a degenerative disease of the brain that results in impaired memory, thinking, and behavior.
Although it is not yet known whether the screen is able to differentiate between Alzheimer's and other types of dementia, it could allow primary-care physicians to quickly identify those patients who need further evaluation. The four components of the test are as follows. Orientation to time Participants are asked to identify the day of the week, month, and year. Clock Drawing Participants are asked to draw the face of a clock showing a specific time. Scoring is accomplished with the help of an accompanying workbook that translates the four scores for the attending physician.