Alternate sources are partial or complete synthesis or plant cell tissue cultures.
Chromatography methods have been developed to isolate and detect taxanes from the above sources on the analytical scale. They use reversed phase C 18 and other bonded phases. Procedures typically require gradient elution. This premium spherical silica serves as support for a proprietary, highly stable bonded phase. The material is now available in analytical columns for process development, and in bulk for the packing of static and dynamic compression columns for scale-up.