I want to. I don't end up trying to manage many partially filled E-Tanks. I'm not getting 10 hours out of it, but more than 6 ordinarily. I have the flow control right there at my fingertips. I typically run it up to 4 if I'm going to be moving around and back down to 2 when I'm idling.
Cannulas are a consideration.
I wish there was a compromise. The length is a little long for when you're carrying it over your shoulder. It forms a loop that catches on every cabinet handle out there. The shorter one of the same model is 4' long but wouldn't reach if you decided to set it on the floor while standing. My oxygen supplier provided me with a 7' cannula with separate hoses but only one tube into each side of your nose.