The increase in total numbers between 1995 and 1996 represents additional reporting centers coming on line. Numbers for 1997 represent total collected for the partial year to Sep 1, 1997. Back to article Figure 2. Virulence traits and their association with enterococcal species. Back to article Figure 3.
Cytolysin favors the appearance of circulating enterococci.
Viable bacteria in liver, spleen, and the bloodstream were enumerated 48 hrs following injection, and significance assessed by Student's t-test. Back to article Figure 4. The cytolysin precursors, CylL L and CylL S, are ribosomally synthesized. Once secreted, CylL L ' and CylL S ' are both functionally inactive until six amino acids are removed from each amino terminus. Since this final catalytic event is essential, occurs extracellularly, and is catalyzed by a class of enzyme for which a substantial body of structural information exists, it represents an ideal therapeutic target.