The immediate applications of transposon tools, however, are readily apparent. One of the more intriguing applications is the ability to stably transpose the genomes of living cells in vivo by direct electroporation of Transposomes. It has been demonstrated that selectable resistance markers can be inserted into and expressed from the genome of bacteria and yeast. An obvious extension of this work is to create custom Transposomes containing any DNA sequence of interest for stable integration into the genome of cultured cells from higher organisms via electroporation, microinjection, or other means. Rev. Microbiol .
Acids Res .