Ability to add, subtract or do other calculations is lost. Sleep cycles fall out of sync. A person may sleep at odd hours and wander at night. Stories or actions are repeated monotonously. At this point, patients are totally dependent and require constant care.
Confusion is acute.
Physical rigidity and seizures may occur. Patients are totally incontinent. Eventually, patients are unable to speak, get out of bed or feed themselves. They become susceptible to malnutrition, infections, pneumonia and other illnesses. Depression may have the appearance of early Alzheimer's and goes hand in hand with dementia in about 20 percent of all cases.