With runners on first and third there is always the possibility of the runner at first attempting to get caught in a rundown. This should be one of the easiest defensed plays in the game if run correctly.
Communication is key.
The pitcher must be alerted as soon as the runner takes off towards second. The pitcher must keep his eye on the runner at third as he steps off the rubber. This action will make the runner on third commit to home or stay at third. If the runner at third commits to home the play is there, if not he turns directly to second base where the second baseman has sprinted to the line between first and second close to but not at the bag. The pitcher throws to the second baseman with no hesitation.