It is a naturally occurring substance which plays a role in the normal control of immune function. One of the most important roles of the immune system is to ward off infection. The T cells are the effector agents. Thus, when a virus invades the body, it is immediately recognized by the immune system which then gears into action to bring about activation of T cells which will specifically recognize and neutralize that virus. This activation process is controlled by a number of so-called humoral agents which are released by the specific cells and then cause activation of other components of the immune system.
Beta interferon is but one of many down regulating humoral factors.
Hence, the use of beta interferon. Thus, in essence, beta interferon does not induce an immunocompromised state such as that would occur with traditional chemotherapy agents such as Cytoxan or Imuran which have a more diffuse effect on the immune system. While beta interferon does reduce the effectiveness of the immune system, this, however, has for the most part not translated itself into a significant problem in patients who take beta interferon. This of course applies to the population in general and it is possible that there may be an increased risk of infection in the specific circumstances mentioned, namely working in close association with immunocompromised patients. Thus there may be a need to adopt protective measures, particularly in those patients who are known to harbor an active infectious process.