An autograft is tissue which is remove from and then re-used on the same individual. Auto-skin grafts can be used as a treatment for 2nd and 3rd degree burns and for reconstructive surgery. Skin autografts are permanent replacement grafts and will heal full thickness burn wounds. Autografts involve the removal the epidermis and some of the dermis but not deep enough to remove the hair follicles and glands. Because autografts are thin and usually don't contain hair follicles or glands, the grafted areas will be devoid of hair and unable to sweat.
Allografts are tissue that is removed from one individual and used on a different individual.
Allograft skin is used as a temporary burn wound graft and will be rejected by the recipient, usually within 7-21 days. Until rejection, however, allograft skin will provide many of the functions of healthy skin. Skin allografts will close a wound providing a barrier against infection and fluid loss, decrease pain, and promote healing of underlying tissues. Skin allografts are use as a transitional treatment until autografting can permanently close the burn wound. Allograft skin may be used fresh or frozen.