To learn about the types of protein aging and degradation. Oxidation of sulfur in Met and Cys 4. Breakdown of disulfide bonds 5. Deamidation of Asn and Gln 6. Regulated degradation A. Regulation of protein activity 1.
Degradation is important to protein conc.
Hemoglobin 90 days 3. Degradation rate is determined by protein sequence and structure a. Proteasomal degradation occurs in cytosol and nucleus c.