The Binding Site is a manufacturer of polyclonal and monoclonal antibodies against a wide range of human and animal proteins. The majority of polyclonal antibodies have been raised in sheep. MAPs are produced by synthesising multiple copies of the chosen peptide sequence, and then attaching them to a non-immunogenic lysine core. The resultant antisera have the specificity associated with monoclonal antibodies, and the high avidity and titre associated with polyclonal antibodies. In some cases the antiserum may undergo further processing to optimise it for a particular procedure, such as nephelometry , turbidimetry , immunoelectrophoresis or immunohistology .
All antibodies are monospecific within a species.
Inter species cross-reactions do occur due to the homology of the target antigen between species. Species adsorbed antisera are available for some specificities. The comparatively small range of mouse monoclonal antibodies is produced in tissue culture and is supplied as purified immunoglobulin fractions. The majority of antisera and conjugates are available in bulk volumes and, if the specificity required is not included in our standard product range, a custom antisera production service is available. For further details or to request a copy of one of The Binding Site catalogues please use the enquiry form .