They also recommend large vitamin doses, mineral and glandular supplements, and amino acids. Thus, the basis for respiratory poisoning and anaerobiasis as causes of cancer had been refuted by 1961, eight years before the first Kelley publication of his theory. Cancer as a deficiency of pancreatic enzymes Since 1961, a vast amount of knowledge has ben gained about the initiation and progression of cancer. Damage to DNA results in the disruption of genetic regulation of oncogens and other enabling genetic mechanisms. Growth of cancer cells is determined by genes, not by nonspecific environmental factors, and the characteristics are passed on to their progeny.
Biliary excretion is a pathway for transformed biometabolites from the liver.
But there is an enterohepatic circulation which returns most of the bile salts to the liver. Thus, if detoxified materials are being carried by these bile salts, they will also be reabsorbed. If coffee enemas were to work as advertised, significant amounts of bile salts would not be efficiently absorbed, would be lost via the stool, and replenishment might be diminished. Fat and fat-soluble vitamins and calcium would then be lost with possible resultant deficiency states as serious consequences. 30 Eisele and Reay reported two deaths from hyponatremia and dehydration linked to coffee enemas.