There are too many unfavorable reactions to ignore. Furthermore Fox's protocells might show the next step. Some molecules, like amino acids are fairly easy to explain in certain scenarios. Others are more difficult. Each successive step in coming up with all the necessary molecules becomes increasingly difficult to explain under natural conditions.
Amino acids are light years from life.
But, I'm willing to listen. There are perfect examples of self reproducing systems that work. I don't know. You have not described such systems. This is closer.