Indian Pediatrics - Editorial Home Past Issue About IP About IAP Feedback Links Author Info. Of the four species infecting humans, Plasmodium falciparum is responsible for potentially fatal infections.
Children suffer most from malaria.
This means a death due to malaria occurs every 30 seconds. In absolute terms, malaria kills 3,000 children under five years old every day. P. vivax is re-emerging in several countries, especially in Europe, with incipient evidence of reduced chloroquine sensitivity in South East Asia and Western Pacific regions. The demonstration of resistance has been based on the results of in vivo tests or the description of prophylactic failure in travellers. In vitro testing can still be conducted in parallel with the therapeutic efficacy test, but only the latter is used in advocating any change to national drug policy.