It's Diablo for the next millennium. This is one game I actually spent some time playing while at E3, about 45 minutes or so, and it seemed like it could ship tomorrow. The gameplay is fast-paced but never seemed overwhelming, and the game is filled with brilliant touches. Secret areas double back and deposit you near the entrance so you don't have to backtrack. Potions are only partially drained to restore full health instead of consumed outright.
Arrows stick in monsters.
Just lasso loot and right click on it to automatically pick it up. The game is designed to maximize fun and minimize tedium. Then to top it off, it will come with a robust editor and multiplayer options. Neverwinter Nights should be a worried. Dungeon Siege turned out a lot better than I would have thought a Diablo clone by Total Annihilation's Chris Taylor would have turned out.