The user has to micromanage things way too often. Carts of goods pile up unless the cart dude is set on the correct path. Roads have to connect everything, which means in many places, you end up paving over paradise. There isn't enough room to build sanctuaries for all the Gods who demand one, because the footprint for the top structures is enormous. I was lucky to get a few slabs set aside for Dionysus.
All elements require absolute perfection and exquisite balance.
Otherwise, it's a mess. Sanctuaries stand half-built, workers go hungry and your popularity wanes. It's enough to drive you nuts. My military power was always pitiful, but it didn't seem to matter. Diplomacy seemed to be out of the question, as my neighbors all hated me.