People use breakpoint reference for a few reasons. When the heads are drier, looking further down the lane helps the ball clear the heads a bit better. Sometimes the backends are a pit spotty. Looking at a breakpoint can help a bowler be accurate in the backend, where accuracy matters in those cases. There are other reasons of course.
Bowlers are very improvisational and come up with new ideas by the game.
Now that you have these points in your mind, draw an imaginary line that goes through the ones that you have decided to focus on. The line does not hook or curve until the breakpoint, which would be the end of the line anyway. When you deliver the ball, try to keep the ball on this line. It will help if you try to get your bowling shoulder above this line when you release the ball. By paying attention to more than one point on the lane, you can become more adept in recognizing the difference between good shots and bad shots, hopefully preventing you from making unnecessary adjustments.