Go with your passion. If you have a passion, then you have something to contribute. Look at issues that relate to your life and your values. That's where you'll have the most passion, the most inspiration, and the most impact. Philanthropy is a team sport.
Complex problems require more than one point of view.
In a company, it takes people from technology, technical support, product marketing, and manufacturing to create a successful product. Any social problem that you work on will also need a diverse team whose members bring different experiences and ideas to the table. Instead, organize a team around solving a problem. Make the team responsible for solving that problem, not for funding programs. Once you know what you're trying to accomplish, then see what role capital can play in accomplishing it.