Diagnosis can be made by immunofluorescent antibody testing or virus isolation, however false negatives are common. The test involves amplification of DNA within the sample to identify the presence of the virus. Unresponsive cases should have an evaluation of the immune system including FeLV and FIV test. Corneal Sequestrum is a form of corneal degeneration unique to the domestic cat. Eosinophilic Keratitis is an immune-mediated inflammatory condition of the feline cornea characterized by a fibrovascular response with or without ulceration.
Diagnosis is made by corneal cytology which demonstrates an eosinophilic infiltrate.
This is one of the rare conditions where topical corticosteroid therapy is indicated even in the face of corneal ulceration. In chronic cases, the lesion may become intensely proliferative and a superficial keratectomy may be required. Long-term therapy is often required and secondary glaucoma is a major concern. Iris melanoma is the most common primary intraocular tumor in cats. Ultimately the iridocorneal angle becomes involved and secondary glaucoma results.