Some patients with severe advanced liver disease will have nearly normal enzyme levels. AP is also found in bone, placenta, and intestine 50 the GGT is used as a supplemental test. The normal level is zero. Bilirubin is the main bile pigment in humans which when elevated, causes the yellow discoloration of the skin and eyes called jaundice. It is taken up from blood processed through the liver and then secreted into the bile by the liver.
Albumin is a major protein produced by the liver.
Chronic liver disease causes a decrease in the amount of albumin produced. Blood clotting factors are proteins made by the liver 50 when the liver is significantly injured, the production of proteins is impaired. There is a good correlation between abnormalities in coagulation measured by the PT test and the degree of liver dysfunction. PT is expressed in seconds and compared to a healthy control patient's blood. The LFTs are used primarily to screen or monitor liver disease.