She had roaring in the ear for three days before the onset of deafness. She had no other medical problems. Five days after the pills were discontinued she reported return of her hearing. In 1968 and 1971 other cases of sudden hearing loss were related to the contraceptive pill. In 133 of the 135 subjects in the study calcium loss doubled after caffeine use.
Caffeine is found in coffee, tea, colas, and chocolate.
The cause of ulcerative colitis is not yet understood, but symptoms have been observed following the use of certain drugs, including nearly all antibiotics, gold salts, phenindione, penicillamine, methyl dopa, cimetidine and methotrexate. A variation of inflammatory bowel disease has been observed with the use of oral contraceptives. The drugs specifically listed in this study included flufenamic acid, mefenamic acid, naproxen and ibuprofen. It is felt that a high HDL cholesterol level is protective for heart disease, while low LDL cholesterol levels are beneficial. The risk for livestock farmers appears to be the greatest, while acute myeloid leukemia risk appeared increased in meat workers.