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Aldosterone regulates the amounts of sodium and potassium in the blood.
This helps maintain water balance and blood volume, which, in turn, affects blood pressure. Purpose Aldosterone measurement is useful in detecting a condition called aldosteronism, which is caused by excess secretion of the hormone from the adrenal glands. Primary aldosteronism is most commonly caused by an adrenal tumor, as in Conn's syndrome. To differentiate primary aldosteronism from secondary aldosteronism, a plasma renin test should be performed at the same time as the aldosterone assay. Renin, an enzyme produced in the kidneys, is high in secondary aldosteronism and low in primary aldosteronism.