Found in the liver, bone, intestines, hepatobiliary tree, and white blood cells, this enzyme is important for assessing both liver and bone disorders. If serum GGT is normal in a patient with bone disease, that means an elevated ALP level probably originates from the liver. Although ammonia levels are insensitive indicators of liver dysfunction, elevated blood concentrations usually correlate with advanced or severe liver disease and are associated with high mortality rates. Both measured together is called Total bilirubin. Bilirubin is nonspecific for liver dysfunction, yet can be used to assess for the causes of jaundice.
Albumin is a nonspecific indicator of liver dysfunction.
Prolonged PT and APTT can indicate liver dysfunction. In severe hepatocellular dysfunction, the liver can't synthesize these factors in normal amounts and their serum concentration decreases. Because synthesis of clotting factors depends on vitamin K, the potential for bleeding intensifies in its absence. But is not the only reason cholesterol levels can vary, a physician will use this finding to support or rule out diagnosis of liver disorder. This test usually called UA is done to check for urinary tract infection and presence of blood, sugar or protein in the urine.