The following options are restricted to UVa internet addresses. If you connect using an Internet Service Provider other than UVA, you will need to use the UVA Proxy Server . Embedded within the ECM are connective tissue cells. The categories of connective tissue proper are based on the relative abundance and appearance of fibers, cells and ground substance. Numerous fibroblasts, macrophages and other cell types are present.
Collagen fibers are inelastic and have very high tensile strength.
Collagen has a distinct amino acid composition. Many different types of collagen have been identified but not all collagens form fiber. Type II forms thin fibrils, found primarily in cartilage. Triple helical domains of Type IV collagens are interrupted by several flexible non-helical regions. These types of diseases include Ehlers-Danlos syndromes, osteogenesis imperfecta, and some forms of osteoarthritis.