Know the mechanisms which regulate bile secretion. What are the primary secretions of the intestine and their importance. Understand the importance of the stem cell division and migration cycle. The Bilary system is part of a liver lobule which is the basic structural and functional unit of the liver. Bile canaliculi are minute channels between hepatocytes into which bile is secreted.
Bile ducts are channels that drain the canaliculi.
Sphincter of Oddi - controls movement of bile and pancreatic secretions into small intestine. Excretory component - bile pigments, bilirubin, drug metabolites. Bilirubin is an end product of hemoglobin degradation, and is actively absorbed from blood by hepatocytes and secreted into cannaliculi with bile salts 2. Bile consists of bile salts, cholesterol, lecithin and fatty acids. Bile salts are the major component.