Common opioid side effects include constipation, nausea, vomiting, and sedation. These symptoms are dispersed within a matter of one to two days. Constipation, however, is a real problem. Side effects can be managed via proactive anticipation and aggressive adjunctive therapy. The same hand that writes the opioid prescription should write the cathartic prescription.
Adjunctive therapy can help buffer opioid side effects.
Neuropathic pain process issues can be addressed with anticonvulsives, tricyclics, and newer anticonvulsive agents. Tramadol has been found useful for this type of pain as well. Gastric distention and rectal spasms can be alleviated with bulk-forming laxatives. Other issues associated with chronic pain include muscle spasms and depression. Pain and depression go hand in hand.