Na to 125 rapidly, then gradually address. Chronic hyponatremia with a normal neurologic exam should be treated much more cautiously to avoid central pontine myelinolysis. In acute hypernatremia, the deficit can be replaced relatively rapidly. Respiratory acid-base disorders have slight effects on potassium. Mineralocorticoids Aldosterone increases distal tubular and collecting duct reabsorption of sodium and secretion of potassium.
Beta agonists increase intracellular uptake of potassium.
Alpha agonists increase potassium release from the liver. Beta blockers decrease cellular uptake and therefore increase serum potassium. Inadequate intake Magnesium depletion. Mg is extracellular. Homeostasis is primarily renal, although control mechanisms are uncertain.