Low set anteverted ears. Downward slanted palpebral fissures, dysplastic eyes, sclerocornea, optic eye atrophy, hypertelorism, and sparse eyebrows. Anteverted nares, long philtrum, and epicanthal folds. Clinodactyly, camptodactyly talipes, and metatarsal abnormalities of the toes.
Dermatoglyphic findings consist of transversae palmar creases.
The syndrome is familial and is transmitted as an X-linked trait.