Birth Defects Birth Defects are abnormal conditions that are present at birth. The number and type vary, depending on family history and the parents' age, race, ethnicity, diet, medical care, and exposure to harmful substances. Some common birth defects are spina bifida, cleft lip, missing arms or legs, and Down syndrome.
Birth defects are a serious problem in Texas and the United States.
Nationally, one in thirty-three babies is born with a birth defect. Approximately 9,000-10,000 babies are born in Texas each year with at least one birth defect. In addition to routine data collection, we conduct investigations of birth defects clusters throughout the state. About 12 to 15 clusters are investigated each year. The Texas Birth Defects Research Center also uses data from the Texas Birth Defects Registry to conduct studies throughout Texas.