Itching is often reported as well as dryness of the skin. An enlarged vulva may be present in females, loss of muscle tone and weakness may be present. Treatment involves surgically removing the tumor. Adrenal tumors are rarely metastatic. The most commonly affected organs are the spleen, liver, and, lymph nodes of the chest and extremities.
Clinical signs are dependent upon the organs affected.
Signs include weight loss, enlarged spleen, lethargy, difficulty breathing, enlarged lymphnodes, and skin tumors. Ferrets have dramatic seasonal changes in the hair coat length, thickness, and color triggered by photoperiod changes. Coats generally get shorter and darker in the summer months and longer , thicker, and lighter in the winter. Abscesses usually occur as the result of a puncture wound or bite wound. Ulcerative pyoderma is the second most commonly encountered form of bacterial dermatitis of the ferret.