This total body fluid is located in several compartments. Cells accomplish homeostasis by exchanging materials with the interstitial fluid, which in turn, exchanges materials with the blood.
Blood composition is regulated as it travels through various body organs.
For example, blood gas levels are restored in the lungs, the kidneys remove metabolic wastes and electrolytes, the digestive system adds nutrients, and so on. Monitoring and maintaining fluid and electrolyte levels is essential to good patient care. Fluid and electrolyte balance is also essential for maximum athletic performance. The kidneys are the organs most responsible for regulating fluid and electrolyte levels. Some other body organs that help regulate fluid and electrolytes are the liver, bones, lungs, various endocrine glands, and the brain.