The symptoms are highly variable. Any part of the nervous system may become involved in neurosarcoidosis. Involvement may be a single nerve, multiple nerves, or generalized. Signs may mimic diabetes insipidus , hypopituitarism , optic neuritis , meningitis , space-occupying lesions such as tumors, or other neurologic disorders. A history of sarcoidosis followed by neurologic symptoms is highly suggestive of neurosarcoidosis.
Blood tests are nonspecific.
If sarcoidosis is suspected but not already known, a chest X-ray often reveals lesions typical of the disorder. Nerve biopsy of affected nerve tissue confirms the disorder. There is no known cure for the disorder. Treatment is indicated if symptoms are severe or progressive. The goal of treatment is to reduce symptoms.