When a person has four or more of these criteria, the diagnosis of systemic lupus erythematosus is suggested. In addition to the eleven criteria, other tests can be helpful in evaluating patients with systemic lupus to determine the severity of organ involvement. There is no cure for Lupus. Many patients with mild symptoms may need no treatment or only intermittent courses of anti-inflammatory medications. Patients with systemic lupus need more rest.
Corticosteroids are particularly helpful when internal organs are involved.
Corticosteroids can be given by mouth, injected directly into the joints and other tissues, or administered intravenously. Unfortunately, corticosteroids have serious side effects when given in high doses over prolonged periods. Side effects include diarrhea, upset stomach, and eye pigment changes. Immunosuppressive medications are used for treating severe cases of systemic lupus with damage to internal organs. All immunosuppressive medications can seriously depress blood cell counts and increase risks of infection and bleeding.