Multiple doses, high dose use and long term use creates even move problems, for example, the freebase has been telling us that we've slept, eaten and drunk though we really haven't so when we stop using, our bodies realize the truth. Other chemicals which control motor co-ordination, sensations, and mental acuity are affected. Smoking cocaine can also cause breathing problems. Smokeable cocaine is of particular danger to the fetus of a pregnant woman. Since cocaine causes increased blood pressure and constriction of the blood vessels supplying the uterus and the placenta, the placenta can prematurely separate from the wall of the uterus causing a miscarriage or premature delivery.
Cocaine abusing mothers are at a greater risk for miscarriage and premature delivery.
In fact, many women have reported feeling contractions and increased fetal activity within minutes of using cocaine, at birth, increased respiratory rates, hyperactivity and agitation are common, other withdrawal symptoms such as lethargy, listless depression and irritability can last anywhere from several days to weeks, there is a 5 to 10 fold increased risk of crib death if the mother uses cocaine during pregnancy. This reaction, which incidentally is not caused by a mental defect in the user, is caused by overstimulation of our fright centre, that part of the brain developed to heighten our senses in times of danger. This intensive use of freebase increases the potential for the abuse of other drugs. The combination of other depressant drugs with freebase has expanded the definition of speedball, which used to be the IV use of heroin and coke, some smokers are putting rocks of freebase in marijuana joints in an other combination called champagne or caviar or gremmies. In addition, users are even mixing PCP with crack in a nasty combination called space basing or whack, when crack is not available, users have switched to shooting and even smoking methamphetamines, a synthetic, powerful stimulant which might not have the same initial intensity as freebase, but which will last for hours.