Most large clinical trials also gather some PK data. For example, partial hepatectomy is an excellent model for understanding complications caused by impaired liver function and invasive abdominal surgery. Follow-on studies could target liver diseases, abdominal surgery prophylaxis or liver transplant. An autoimmune disease where T cells stimulate the body's own skin cells. Initial preclinical and Phase I healthy adult studies reported in the literature were performed with rBPI-23.
Bacteremia means the detectable presence of bacteria in the bloodstream.
Meningococcemia is a septicemia caused by meningococcal bacteria. Septic shock refers to the dangerously low blood pressure caused by sepsis. The order in which amino acids occur in a protein or peptide. Sequences uniquely define a particular peptide or gene sequence and can sometimes be patented. In autoimmune diseases T cells mistake the body's own cells for foreign cells and attack them.