Some extracts show marked anti-inflammatory tendencies. Manaca has been used to treat conditions associated with sexually transmitted infections. It also disperses uric acid. Brunfelsia grandiflora D. Don ssp. Sometimes cultivated as an ornamental or medicinal plant.
Curanderos add it to ayahuasca or to prepare special initiations.
Also used for bad luck. Root infusion with aguardiente for rheumatism and venereal diseases. The main phytochemical is scopoletin, which induces psychopharmacologic effects. This woody shrub is a multipurpose plant found only in the wild. Since this subspecies is widely cultivated for medicinal and ornamental purposes, some activity of man has undoubtedly influenced its present distribution.