But every composition is different. Some must be rammed or pressed to work properly. Other will explode when rammed. Some must be wet with water, others may spontaneously ignite when wet. Some mixtures are relatively safe to use by themselves but are extremely sensitive when used together.
Accidents happen even in places where every conceivable safety precaution is taken.
It'll increase your safety. Be sure you are familiar with all the properties of the compositions you work with. Thoroughly test new compositions for sensitivity, stability, compatibility with other mixtures etc, until you are absolutely sure that the mixture is ok to use in your application and method of construction. Find out as much as you can about other peoples experiences with a particular mixture. Use only non-sparking tools.