Initially slight dehydration and increased respiratory rate. No response to antibiotics. Similar gross lesions in all five. Severe mesocolonic edema and ascites. Congestion of colonic serosa and mucosa.
Colonic lumen contains variable amounts of green semifluid to solid or dry fecal material.
Clostridium difficile toxins were demonstrated in colonic contents by mouse inoculations. Mouse protection achieved with specific antiserum. Diffuse acute colitis and edema. Multifocal erosive fibrinonecrotizing colitis. Severe edema and inflammation of mesocolon.