Patients receive PET scans of the head during the eighth week of the study. This program is designed for people who are currently depressed and have had problems with depression in the past. Treatment involves the medication clomipramine and lasts for 16 weeks. The Clinical Research Center for Mood Disorders offers outpatient treatment for individuals age 60 and older experiencing depression and other mood disorders. Pregnant women may be accepted.
Clients receive interpersonal psychotherapy for two years or longer.
Maintenance Therapies in Bipolar Disorder Study People over the age of 18 who have been diagnosed with bipolar disorder are eligible for this program. Treatment involves the medication lithium and either Interpersonal Social Rhythm Therapy or Clinical Status and Symptom Response Therapy. Participants receive treatment for two years or longer. A wide variety of medication treatments are being utilized. Treatment involves antidepressant medication and lasts for 24 weeks.