The nature preserve is south of the road. This prairie is characterized by loess covered hillsides and elevations that vary from 600 feet on the ridge tops to 500 feet in the ravines. Typical loess hill prairie vegetation includes sideoats grama, little bluestem, and silky aster. Unusual plants to see are pink milkwort and Hill's thistle. Like most hill prairies, Meredosia is being invaded by woody vegetation.
Current management involves removal of the black locust and shrubs and occasional burns.