Clinical depression is more serious than simply feeling blue. Poor appetite and weight loss or increased appetite with weight gain. The presence of five of these eight symptoms definitely indicates clinical depression. Those exhibiting four symptoms are probably depressed. There are several types of clinical depression.
Bipolar depression occurs when depressed states alternate with manic states.
Neither St. John's Wort nor Prozac has shown much promise for Bipolar depression. A total of 1,592 patients have been studied in 25 controlled, doubleblind experiments. In 15 of these experiments, St. John's Wort was compared to a placebo. In the remaining ten studies, St. John's Wort was compared to antidepressant drugs. The study lasted four weeks.