Exercise is important. Improves cardiovascular risk factor. Augments weigh reduction efforts. Improves glucose control by increasing insulin sensitivity. Reduces dosage or need for insulin or hypoglycemic agents.
Combinations are usually more effective than monotherapy.
Intensification of insulin therapy can be done with insulin pumps. Sulfonylureas - stimulate insulin secretion from islet cells, effective and widely used 1. Second generation, more potent. Secondary rate of failure is about the same as sulfonylureas alone. Combined use with diet or a sulfonylurea can be very effective.