Review of Remifemin - Black Cohash for Menopause By Murray, Michael. American Journal of Natural Medicine, Vol. 4, No. 3, April 1997, pp. From the American Botanical Council HerbClip.
Black cohosh is native to the eastern U.S. and Canada.
Remifemin contains 1 mg. of triterpenes, calculated as 27-deoxyacteine per tablet. The attached editorial attempts to answer questions generated by an earlier review of Remifemin clinical study results published in the same journal. Remifemin s phytoestrogens and other active components impact endocrine regulatory systems. Its effect seems similar to one of the milder endogenous estrogens, estriol, in that it binds with estrogen receptors fairly weakly and for a short duration, and apparently exerts its effects on the vaginal lining. On the other hand, estradiol, an estrogen whose synthetic form is commonly prescribed for menopause, binds receptors more aggressively, exerts its effects primarily on the uterine lining, and is associated with an increased risk of breast, ovarian, and endometrial cancers.