Compression involves holding an object, or pushing down on an instrument. If a chemical degrades or softens a glove it will make it easier to rupture, split or depending on the chemical, disintegrate. Another type of compression or deflective activity involves torsion stress. Examples of torsion stress include manipulating luer locks, IV tubing and surgical instruments. These stresses are amplified when subjected to chemical challenges.
Disinfectants are some of the most common chemical challenges encountered by medical gloves.
Disinfectants like alcohols, quaternary amines and surfactants work by reducing the surface tension. This can cause glove cells to lyse. The alcohols can readily permeate and degrade natural rubber. Included here are some common examples of disinfectants. Bleach Povidone Iodine Solutions Glutaraldehyde solutions are used for chemical sterilization and are known to slightly weaken natural rubber gloves.