However, the beta cell responds to the presence of the insulin resistance by augmenting its secretion of insulin and providing that the beta cell can maintain its high response of insulin secretion, glucose tolerance remains with-in a normal range. Diet and exercise are the cornerstones of therapy in Type 2 Diabetes Mellitus. No pharmacological intervention will be successful in achieving normal blood glucose levels in the absence of diet and exercise. The obese diabetic who can lose and maintain a 20-30 lb. weight loss will achieve marked improvement in insulin sensitivity and a decrease in mean plasma glucose levels. This is true despite still being well above ideal body weight.
Aerobic exercise is best for most patients.
The goal is 30 minutes per day of some form of exercise that can be continued indefinitely.