Since the Mamu AG molecule is hypothesized to modulate the maternal immune system, additional potential significance may be in transplant biology. Scientists cannot study the interactions of the maternal immune system with the placenta without using pregnant animals. The nonhuman primate model also allows researchers to look at the very earliest time during pregnancy, the implantation stage, when the most critical events for the establishment of pregnancy are occurring. This is the time when most embryonic loss occurs in humans, yet this very early time in pregnancy cannot be directly studied with human clinical samples. I molecule Mamu-AG at implantation in the rhesus monkey.
Coverage includes biomedicine, behavior, conservation and veterinary science.
Primate-Science Research Highlights are supported by a grant from the National Institutes of Health, National Center for Research Resources. Copyright 2000, Wisconsin Regional Primate Research Center. No portion of this highlight may be copied or redistributed without the consent of the editor.