Utilizing the neurophysiology laboratory, we are developing new ideas and techniques for the diagnosis of focal entrapment neuropathies, as well as generalized polyneuropathy. Paul H. McCabe, M.D . My main interest is in epilepsy, a disorder which still remains misunderstood in today's society. Investigative techniques utilize microdialysis combined with the kindling model of epilepsy. Future goals would be to apply this technique to human studies.
Clinical research includes surgical treatment of epilepsy and experimental medications.
Both of these are important to our population of patients, since many have already failed more traditional means of treatment. Also, the relationship of epilepsy and psychiatric disturbances is of interest to me. I am attempting to adapt this to the study of dystonia patients, a large segment of my clinical population, in order to analyze the behavior of their motor unit population both before and after the administration of Botulinum Toxin treatment. My main area of interest is in acute stroke treatments. We also use intravenous t-PA, the only approved acute stroke therapy, when appropriate.