Chronic toxicity studies on Tolylfluanid were done in the rat, mouse and dog. Tolylfluanid was tested in two rat chronic dietary studies. Hepatotoxicity and renal toxicity were seen in rats, mice, and dogs. Nobody ever thought about setting it in context with other fluoride intake, such as fluoridated water, or cryolite. In the case of apples, this is of immediate concern.
Apple juice is drunk by many children on a daily basis, particularly infants.
A national survey of pediatric health professionals confirms that apple juice is the first juice most often recommended for infants. Maybe they should talk to an endocrinologist about that. We have infants, the most highly exposed group according to the Federal Register, consuming high amounts of Tolylfluanid on a daily basis. Tolylfluanid causes thyroid dysfunction and thyroid cancer. Proper thyroid function is essential for the developing brain.