The lead compounds are approximately 30 times more active than diazepam in anti-anxiety tests, but with no effect on learning and memory, no sedation, and no loss of muscle strength.
Benzodiazepines are the most widely prescribed drugs throughout the world.
They are commonly used to treat anxiety and related conditions, but they suffer from serious side effects. Benzodiazepines cause sedation and memory impairment, which can limit their usefulness as anxiolytics, and repeated administration causes the development of tolerance to their effects and withdrawal symptoms when treatment is stopped. SIDR identifies early-stage commercial opportunities in drug research, develops them through proof of principle stage, and seeks industrial partners for full development. Now in its 13th year of operation, SIDR has extensive experience of working with pharmaceutical and biotech companies in Europe, USA and Japan.