Material can remain inside a vesicle or outside cell at all times. Click here for animation. Membrane starts to invaginate to form coated vesicle . A single vesicle can contain more than one type of receptor plus ligand. Uncoated, acidified vesicle can be called an endosome, early endosome, or sorting vesicle.
Acidification requires energy for proton pump.
Fate of vesicle with material that was endocytosed. Some Specific Examples 1. What cell actually needs is the cholesterol part. Receptor, but not carrier, is recycled. Sometimes called late endosome.