My studies have focused on revealing the behavioral laws and identifying the neural substrates of learning and memory as well as examining the synaptic plasticity that occurs at these substrates. I use classical conditioning as my behavioral paradigm and electrophysiology and functional imaging as ways of recording the changes that learning induces in brain. Kinetic and frequency-domain properties of reflex and conditioned eyelid responses in the rabbit. Functional networks underlying human eyeblink conditioning. The effects of scopolamine on regional cerebral blood flow during classical conditioning of the human eyelid response.
Classical conditioning increases membrane-bound protein kinase C in rabbit cerebellum.
Long-term memory and extinction of rabbit nictitating membrane trace conditioning.