Our laboratory is interested in understanding the mechanisms underlying DNA damage responses in eukaryotes. Most of our work uses the fission yeast as a model system. Our current interests include studies on the SUMO-1 modification system in fission yeast, and its role in the DNA damage response. In particular we are involved in identifying SUMO-1 modified targets that are required for the response to DNA damage. We are also interested in the role of the Rhp9, a protein that contains two BRCT domains.
Acids Res .
The role of Schizosaccharomyces pombe Rad32 and other DNA damage response proteins in non-homologous end joining and telomere length maintenance. Acids Res .