Document ID: EPA-HQ-OPP-2004-0167-0015
Agency: epa
Document Type: Supporting & Related Material
Title: 
Posted Date: 2004-05-20T04:00Z

Appendix
H
­
2,4­
D
Swimmer
Exposures
Spreadsheet
H1
­
Acute
Exposures
at
4
ppm
Dermal
Exposure
2,4­
D
Form
Exposed
Person
Concentration
in
Water
(
mg/
l)
Exposed
Surface
Area
(
cm2)
Exposure
Time
(
Hours/
day)
Kp
(
cm/
hr)
Conversion
factor
(
L/
1000
cm3)
Absorbed
Dose
(
mg/
kg/
BW)
Acute
MOE
Acid
Child
­
22
kg
4
9000
3
0.000025
0.001
0.00012
545926
DMA
Child
4
9000
3
0.000013
0.001
0.00006
1041843
BEE
Child
4
9000
3
0.0171
0.001
0.08
798
Ingestion
Exposure
2,4­
D
Form
Exposed
Person
Concentration
in
Water
(
mg/
l)
Ingestion
Rate(
L/
hr)
Exposure
Time
(
Hours/
day)
Absorbed
Dose
(
mg/
kg/
BW)
Acute
MOE
All
Child
­
22
kg
4
0.05
3
0.0273
2457
Combined
Exposure
2,4­
D
Form
Exposed
Person
Acute
Combined
MOE
Acid
Child
­
22
kg
2446
DMA
Child
2451
BEE
Child
602
Notes
Kp
values
are
from
Table
2­
3
of
the
USFS
Risk
Assessment
for
2,4­
D
The
Acute
NOAEL
is
67
mg/
kg/
day
for
children
Appendix
H
­
2,4­
D
Swimmer
Exposures
Spreadsheet
H2
­
Acute
Exposures
at
2
ppm
Dermal
Exposure
2,4­
D
Form
Exposed
Person
Concentration
in
Water
(
mg/
l)
Exposed
Surface
Area
(
cm2)
Exposure
Time
(
Hours/
day)
Kp
(
cm/
hr)
Conversion
factor
(
L/
1000
cm3)
Absorbed
Dose
(
mg/
kg/
BW)
Acute
MOE
Acid
Child
­
22
kg
2
9000
3
0.000025
0.001
0.00006
1091852
DMA
Child
2
9000
3
0.000013
0.001
0.00003
2083687
BEE
Child
2
9000
3
0.0171
0.001
0.04
1596
Ingestion
Exposure
2,4­
D
Form
Exposed
Person
Concentration
in
Water
(
mg/
l)
Ingestion
Rate(
L/
hr)
Exposure
Time
(
Hours/
day)
Absorbed
Dose
(
mg/
kg/
BW)
Acute
MOE
All
Child
­
22
kg
2
0.05
3
0.0136
4913
Combined
Exposure
2,4­
D
Form
Exposed
Person
Acute
Combined
MOE
Acid
Child
­
22
kg
4891
DMA
Child
4902
BEE
Child
1205
Notes
Kp
values
are
from
Table
2­
3
of
the
USFS
Risk
Assessment
for
2,4­
D
The
Acute
NOAEL
is
67
mg/
kg/
day
for
children
The
Actute
NOAEL
is
25
mg/
kg/
day
for
adults
Appendix
H
­
2,4­
D
Swimmer
Exposures
Spreadsheet
H3
­
Short
Term
Exposures
at
4
ppm
Dermal
Exposure
2,4­
D
Form
Exposed
Person
Concentration
in
Water
(
mg/
l)
Exposed
Surface
Area
(
cm2)
Exposure
Time
(
Hours/
day)
Kp
(
cm/
hr)
Conversion
factor
(
L/
1000
cm3)
Absorbed
Dose
(
mg/
kg/
BW)
Short
Term
MOE
Acid
Adult
­
60
kg
4
21000
3
0.000025
0.001
0.00011
238095
Acid
Child
­
22
kg
4
9000
3
0.000025
0.001
0.00012
203704
DMA
Adult
4
21000
3
0.000013
0.001
0.00006
454380
DMA
Child
4
9000
3
0.000013
0.001
0.00006
388748
BEE
Adult
4
21000
3
0.0171
0.001
0.07
348
BEE
Child
4
9000
3
0.0171
0.001
0.08
298
Ingestion
Exposure
2,4­
D
Form
Exposed
Person
Concentration
in
Water
(
mg/
l)
Ingestion
Rate(
L/
hr)
Exposure
Time
(
Hours/
day)
Absorbed
Dose
(
mg/
kg/
BW)
Short
Term
MOE
All
Adult
­
60
kg
4
0.05
3
0.0100
2500
All
Child
­
22
kg
4
0.05
3
0.0273
917
Combined
Exposure
2,4­
D
Form
Exposed
Person
Short
Term
Combined
MOE
Acid
Adult
­
60
kg
2474
Acid
Child
­
22
kg
913
DMA
Adult
2486
DMA
Child
915
BEE
Adult
306
BEE
Child
225
Notes
Kp
values
are
from
Table
2­
3
of
the
USFS
Risk
Assessment
for
2,4­
D
The
short
term
NOAEL
is
25
mg/
kg/
day
for
children
based
upon
maternal
effects
observed
during
the
developmental
study.
The
short
term
NOAEL
is
25
mg/
kg/
day
for
adults
based
upon
developmental
effects
observed
during
the
developmental
study.
Appendix
H
­
2,4­
D
Swimmer
Exposures
Spreadsheet
H4
­
Short
Term
Exposures
at
2
ppm
Dermal
Exposure
2,4­
D
Form
Exposed
Person
Concentration
in
Water
(
mg/
l)
Exposed
Surface
Area
(
cm2)
Exposure
Time
(
Hours/
day)
Kp
(
cm/
hr)
Conversion
factor
(
L/
1000
cm3)
Absorbed
Dose
(
mg/
kg/
BW)
Short
Term
MOE
Acid
Adult
­
60
kg
2
21000
3
0.000025
0.001
0.00005
476190
Acid
Child
­
22
kg
2
9000
3
0.000025
0.001
0.00006
407407
DMA
Adult
2
21000
3
0.000013
0.001
0.00003
908760
DMA
Child
2
9000
3
0.000013
0.001
0.00003
777495
BEE
Adult
2
21000
3
0.0171
0.001
0.04
696
BEE
Child
2
9000
3
0.0171
0.001
0.04
596
Ingestion
Exposure
2,4­
D
Form
Exposed
Person
Concentration
in
Water
(
mg/
l)
Ingestion
Rate(
L/
hr)
Exposure
Time
(
Hours/
day)
Absorbed
Dose
(
mg/
kg/
BW)
Short
Term
MOE
All
Adult
­
60
kg
2
0.05
3
0.0050
5000
All
Child
­
22
kg
2
0.05
3
0.0136
1833
Combined
Exposure
2,4­
D
Form
Exposed
Person
Short
Term
Combined
MOE
Acid
Adult
­
60
kg
4948
Acid
Child
­
22
kg
1825
DMA
Adult
4973
DMA
Child
1829
BEE
Adult
611
BEE
Child
450
Notes
Kp
values
are
from
Table
2­
3
of
the
USFS
Risk
Assessment
for
2,4­
D
The
short
term
NOAEL
is
25
mg/
kg/
day
for
children
based
upon
maternal
effects
observed
during
the
developmental
study.
The
short
term
NOAEL
is
25
mg/
kg/
day
for
adults
based
upon
developmental
effects
observed
during
the
developmental
study.
Data
Source
1
2
3
4
5
6AVG
(
1
to
6)
DAT
PPM
PPM
PPM
PPM
PPM
PPM
PPM
0
4.0
4.0
4.0
4.0
4.0
4.0
4.0
1
3.9
3.9
3.9
3.7
3.2
3.1
3.6
2
3.8
3.7
3.6
3.3
2.1
1.8
2.9
3
3.7
3.4
3.3
2.6
1.1
0.84
2.2
4
3.5
3.1
2.8
2.0
0.47
0.30
1.4
5
3.3
2.7
2.4
1.4
0.16
0.08
0.9
6
3.0
2.4
2.0
0.94
0.04
0.02
0.5
AVG
3.6
3.3
3.1
2.6
1.6
1.5
2.2
GM
3.6
3.3
3.0
2.3
0.72
0.50
1.8
Data
SourceForm
Location
Slope
Factor
1
BEE
NC
­
0.013
2
DMA
NC
App
1
­
0.025
3
DMA
NC
App
2
­
0.034
4
DMA
ND
App
1
­
0.069
5
DMA
ND
App
2
­
0.215
6
DMA
MN
Lake
­
0.26
AVG
­
0.10