Document ID: EPA-HQ-OPP-2002-0188-0010
Agency: epa
Document Type: Supporting & Related Material
Title: 
Posted Date: 2002-09-16T04:00Z

HEXAZINONE
TOLERANCE
REASSESSMENT
ELIGIBILITY
DECISION
ACUTE
AND
CHRONIC
DIETARY
RISK
ASSESSEMENT
DATED
05/
14/
2002
DuPONT
COMMENTS:

General
comments
­
Dietary
Risk
Assessment
1.
An
acute
endpoint
is
only
given
for
females
13­
50.
We
assume
this
group
is
considered
by
EPA
to
be
the
most
sensitive
sub­
population.

2.
In
several
places
we
note
the
risk
assessment
is
'based
on
the
reassessed
tolerances
for
blueberry,
pineapple,
and
sugarcane.
'
For
blueberries
and
pineapple
0.3
ppm
is
utilized,
presumably
one­
half
of
the
new
proposed
tolerance
of
0.6ppm.
However,
for
sugarcane
0.6
ppm
(tolerance)
is
utilized.
This
appears
to
be
an
inconsistency.
Stated
differently,
it
is
not
clear
to
us
why
0.3ppm
was
selected
for
blueberry
and
pineapple
while
0.6
was
selected
for
sugarcane.

3.
Clarity
is
needed
around
the
definition
of
LOQ.
There
are
both
enforcement
methods
(sum
of
LOQs
is
0.55
ppm)
and
data
collection
methods
(sum
of
LOQs
is
0.3
ppm).
We
recommend
that
the
enforcement
LOQs
be
used
consistently
throughout
the
document.

4.
We
note
that
a
more
up
to
date
consumption
database
exists,
CSFII
94­
96/
98.
Why
was
the
older
database,
CSFII
89­
92,
used?

Editorial
Comment
­
Typo:
p2
Third
full
paragraph,
2nd
line
from
bottom:
residue