Document ID: EPA-HQ-OW-2004-0032-0804
Agency: epa
Document Type: Supporting & Related Material
Title: 
Posted Date: 2005-08-18T04:00Z

1Reference
numbers
37,
311,
and
314.

2ERG,
2004.
"
Toxic
Weighting
Factors
(
TWFs)
Database:
Preliminary
Working
Version,"
Memorandum
to
Lynn
Zipf,
EPA
from
Ian
Cadillac
and
Maureen
F.
Kaplan,
ERG,
dated
June
12.

1
Date:
November
1,
2004
To:
Lynn
Zipf,
EPA
From:
Ian
Cadillac,
Sarah
Dun,
and
Maureen
F.
Kaplan,
ERG
Subject:
Fixes
to
Toxic
Weighting
Factor
(
TWF)
Data
The
TWF
database
delivered
to
EPA
for
the
2004/
2005
effluent
guideline
program
plan
on
August
25,
2004
replicated
the
TWFs
developed
by
Versar
based
on
the
data
Versar
provided
in
March
2004.
We
completed
the
conversion
of
codes
to
citations,
species
names,
etc.
based
on
the
information
provided
by
Lynn
Zipf
in
her
project
notebook
in
August
2004.
Versar
has
since
provided
citations
for
three
references1
which
existed
in
the
data
file
but
not
on
any
reference
list
available
to
us.

ERG
performed
quality
control
inspections
to
identify
inconsistences
and
gaps
that
should
be
fixed
prior
to
updating
the
database.
ERG
began
this
process
in
June
2000
(
ERG,
2004).
2
This
memorandum
documents
what
we
found
and
proposes
how
to
correct
each
item.
Section
1
covers
the
exceptions
discussed
in
ERG
2004.
Section
2
describes
multi­
chemical
changes
to
make
the
database
consistent
and
bring
it
up
to
date.
Section
3
lists
fixes
for
missing
codes
(
i.
e.,
there
is
an
entry
in
the
Versar
file
but
it
doesn't
match
any
of
the
codes
listed
in
the
Lynn
Zipf
notebook).
Section
4
lists
fixes
for
individual
chemicals.
Section
5
lists
items
to
add
to
the
Notes
sheet.
To
make
the
text
easier
to
read,
all
tables
appear
at
the
back
of
the
memorandum.

ERG
will
make
these
changes
and
revisions
once
we
heard
that
EPA
has
approved
them.

1.
INTERNAL
MISMATCH
BETWEEN
DATA
IN
VERSAR
DATABASE
AND
TWF
CONTAINED
IN
VERSAR
DATABASE
These
inconsistences
were
first
identified
in
ERG,
2004.
Here,
we
discuss
how
we
propose
to
fix
them.

1.1
Adjustment
of
Risk
Level
to
10­
5
for
Carcinogens
Table
1
is
a
list
of
14
chemicals
for
which
Versar
had
a
q1*
entry
but
did
not
adjust
the
water
quality
criterion
for
human
health
from
a
10­
6
risk
level
to
a
10­
5
risk
level.
To
assess
this
discrepancy,
ERG
reviewed
carcinogenicity
data
for
each
pollutant
to
identify
appropriate
q1*
values.
For
the
14
chemicals,
ERG
found:
3NRWQC.
2002.
United
States
Environmental
Protection
Agency.
National
Recommended
Water
Quality
Criteria:
2002.
EPA­
822­
R­
02­
047.
November.

2
#
Two
chemicals
are
listed
as
likely
or
possible
carcinogens
in
IRIS
and
should
be
adjusted
to
a
10­
5
risk
level.
(
Allyl
chloride
and
Dichloropropene
1,
3­)

#
Three
chemicals
could
not
be
confirmed
as
carcinogens,
and
should
not
be
adjusted
to
a
10­
5
risk
level.
The
outdated
q1*
values
should
be
removed
from
the
TWF
database
(
Mirex/
Dechlorane
and
Tetrachlorvinphos\
Gardona\
Stirofos
under
two
CAS
numbers).

#
Nine
chemicals
have
IRIS
summaries
stating
that
an
assessment
of
carcinogenicity
is
not
available
at
this
time.
HEAST
q1*
values,
however,
are
available
from
the
EPA
Region
3,
Risk­
based
Concentration
(
RBC)
Table.
A
possible
interpretation
is
that
Versar
decided
that
these
chemicals
should
be
treated
as
non­
carcinogens
based
on
their
IRIS
summaries,
and
so
did
not
adjust
the
q1*
values.
As
such,
Versar
should
have
removed
the
q1*
values
from
the
database
to
be
consistent.
ERG
recommends
using
the
HEAST
q1*
values
presented
in
the
EPA
Region
3,
RBC
Table
and
adjusting
to
a
10­
5
risk
level.
(
Bis
(
2­
chloroisopropyl)
ether;
Simazine;
BHC,
gamma­\
Lindane\
HCH,
gamma­;
Trichloropropane,
1,2,3­;
Ethylenethiourea;
Alachlor/
Lasso;
Tetrachloroethene;
Atrazine;
and
Chlorobenzilate)

Table
1
lists
each
of
the
14
chemicals
reviewed;
the
q1*
and
source
presented
by
Versar;
comments
regarding
the
availability
of
more
recent
data
in
the
EPA
Integrated
Risk
Information
System
(
IRIS)
(
http://
www.
epa.
gov/
iris/)
and
the
EPA
Region
3,
RBC
Table
(
http://
www.
epa.
gov/
reg3hwmd/
risk/
human/
index.
htm),
which
lists
IRIS,
HEAST,
NCEA
provisional
and
other
toxicity
values;
and
recommendations
for
modifying
the
ERG
TWF
database.

1.2
Versar
Calculated
a
TWF
But
Did
Not
Use
All
Data
Available
Table
2
lists
the
five
pollutants
for
which
Versar
calculated
a
TWF.
The
TWF,
however,
was
based
either
on
human
health
or
aquatic
health
even
though
the
Versar
database
contained
entries
for
both
human
and
aquatic
health.

ERG
reviewed
the
data
sources
listed
in
the
Versar
database
to
determine
the
possible
cause
of
these
discrepancies.
For
each
of
the
five
chemicals,
Table
2
lists
the
human
health
and
aquatic
values
and
the
sources
listed
in
the
Versar
database.
ERG
also
reviewed
NRWQC,
2002
to
identify
if
more
recent
values
were
available.
3
In
general,
ERG
concurs
that
the
human
health
component
of
the
toxic
weighting
factor
should
be
set
to
zero
for
four
pollutants.
For
two
pollutants
 
barium
and
iron
 
NRWQC
2002
notes
that
a
major
reassessment
may
be
warranted.
For
2,
6­
dichlorophenol,
the
value
in
the
Versar
database
is
for
organoleptic
effects.
Organoleptic
effects
(
taste,
odor,
etc.)
are
not
part
of
the
human
health
toxicity
calculations.
There
is
no
associated
reference
for
the
human
health
value
for
ethoprophos.
It
is
not
a
4Versar
calculated
a
TWF
based
on
the
human
health
value
for
ethoprophos
but
not
the
aquatic
value.
While
the
data
for
the
aquatic
value
are
old,
the
data
source
(
National
Recommended
Water
Quality
Criteria,
1972)
is
used
for
multiple
chemicals
in
the
database.
ERG
recommends
that,
for
now,
the
data
should
be
retained
for
the
moment
and
considered
in
the
general
update
review
of
the
database
contents.

5Verschueren.
1983.
Karel
Verschueren.
Handbook
of
Environmental
Data
on
Organic
Chemicals.
Van
Nostrand
Reinghold:
New
York.
2nd
Edition.

6NRWQC.
1972.
United
States
Environmental
Protection
Agency.
National
Recommended
Water
Quality
Criteria;
Neely.
1983.
M.
Neely.
Versar
Inc.,
Springfield,
VA.
Memorandum
to
R.
Healy,
U.
S.
Environmental
Protection
Agency.

3
priority
pollutant,
so
it
is
not
included
in
NRWQC,
2002,
so
ERG
did
not
rapidly
identify
an
updated
source
for
the
data.
4
ERG
cannot
justify
using
a
value
without
a
reference.

For
p­
ethylphenol,
the
data
source
for
human
health
is
more
than
30
years
old,
5
however,
the
source
is
used
for
multiple
chemicals
in
the
database.
ERG
recommends
that,
for
now,
the
data
should
be
retained
for
the
moment
and
considered
in
the
general
update
review
of
the
database
contents.

1.3
Versar
File
Contained
Data
But
Versar
Did
Not
Calculate
a
TWF
Table
3
lists
18
chemicals
for
which
the
Versar
TWF
database
contained
data
for
calculating
a
TWF,
but
no
TWF
was
included.
ERG
performed
the
same
review
for
these
chemicals
as
it
did
for
those
listed
in
Section
1.2;
likewise,
Table
3
follows
the
same
organization
as
Table
2.

For
each
of
these
chemicals,
except
nitrate,
the
data
sources
were
more
than
30
years
old,
data
were
of
questionable
quality,
or
no
source
was
referenced.
For
nitrate,
the
only
value
presented
was
for
human
health
water
and
organism,
which
is
consistent
with
the
value
presented
in
the
NRWQC
2002.
This
value
will
remain
unchanged
and
ERG
will
calculate
a
TWF
based
on
this
information.
For
the
other
chemicals:

#
For
data
with
no
source
listed
for
any
of
the
values,
e.
g.,
Nitroso­
N­
methylurea,
N­,
ERG
recommends
deleting
the
value
from
the
database.

#
For
chemicals
where
the
only
information
is
from
older
data
sources,
ERG
recommends
deleting
the
values
and
calculating
a
TWF
with
the
understanding
that
these
chemicals
will
be
examined
for
updates
at
a
later
time
(
e.
g.,
NRWQC
1972;
Verschueren,
1983;
Neely,
1983).
6
(
Indole,
Ethylphenol,
o­,
and
Dibenzo(
a,
h)­
pyrene)

#
For
the
remaining
chemicals,
data
are
present
only
for
salt
water
aquatic
values.
These
also
have
references
that
might
be
questionable
(
listed
as
other).
For
now,
ERG
recommends
deleting
the
values.
4
5
2.
MULTI­
CHEMICAL
CHANGES
2.1
Acute:
Chronic
Ratios
The
Versar
database
has
two
codes
for
chronic
values:

#
@
A10:
estimated
from
acute
value
using
acute:
chronic
ratio
of
10.

#
@
AAB:
estimated
from
acute
value
using
acute:
chronic
ratio
of
100.

When
we
examined
the
@
AAB
entries,
we
found
that
all
but
one
of
them
used
an
acute:
chronic
ratio
of
10.
This
meant
we
had
two
codes
for
the
same
relationship.

The
ERG
TWF
database
does
not
contain
codes.
ERG
changed
all
@
AAB
and
@
A10
entries
to
read;
"
Estimated
from
acute
value
using
acute:
chronic
ratio
of
10;
see
U.
S.
EPA.
Technical
Support
Document
for
Water
Quality­
based
Toxics
Control.
EPA
505/
2­
90­
001.
March
1991."
This
change
affected
370
chemicals.
In
addition,
we
updated
the
one
chemical
with
the
acute:
chronic
ratio
of
100
to
an
acute:
chronic
ratio
of
10.

2.2
Reference
Correction
Versar
reference
180
is
listed
as:
USEPA.
1987.
U.
S.
Environmental
Protection
Agency.
Acute
toxicity
handbook
of
chemicals
to
estuarine
organisms.
Gulf
Breeze,
FL:
Office
of
Research
and
Development,
Environmental
Research
laboratory,
USEPA.
EPA/
800/
8­
87/
017.
The
correct
EPA
document
number
is
EPA/
600/
8­
87/
017.
We
will
make
the
correction
in
all
entries.

2.3
Transferring
Species
Names
As
mentioned
in
Section
2.1,
aquatic
chronic
values
are
sometimes
scaled
from
aquatic
acute
values.
Where
this
happens,
ERG
performed
temporary
coding
to
copy
the
name
of
the
species
from
the
sheet
with
acute
data
to
the
appropriate
spot
on
the
sheet
for
chronic
data.
This
means
that
each
sheet
should
contain
species
information
where
it
is
available.

2.4
Missing
Species
Codes
The
1980
Water
Quality
Criteria
documents
don't
list
a
species.
Wherever
EPA,
1980
is
given
as
a
source,
we
have
completed
blanks
with
"
None
listed."

3.
MISSING
OR
UNKNOWN
CODES
BY
ERG
TWF
DATABASE
SHEET
By
"
missing,"
we
mean
that
the
cell
is
blank
in
the
Versar
data.
By
"
unknown,"
we
mean
that
there
is
an
entry
but
that
we
could
not
find
the
entry
on
any
of
the
lists
supplied
by
Lynn
Zipf.
Where
possible,
we
looked
up
the
original
reference
and
will
enter
the
data.
On
October
20,
2004,
EPA
arranged
for
ERG
to
have
access
to
ASTER
data
to
complete
this
section.
6
The
tables
are
organized
as:

#
Table
4:
Freshwater
Aquatic
Acute
#
Table
5:
Freshwater
Aquatic
Chronic
#
Table
6:
Saltwater
Aquatic
Acute
#
Table
7:
Saltwater
Aquatic
Chronic
#
Table
8:
Bioconcentration
Factors
4.
Fixes
for
Individual
Pollutants
4.1
Dichloroethene,
1,2­
(
CAS
540590)

What
we
have
Probable
Source
What
we'd
like
to
show
Oral
reference
dose
of
9.00e­
3
with
no
reference.
We
found
an
oral
minimal
risk
level
(
MRL)
of
9.00e­
3
mg/
kg/
day
for
1,1
dichloroethene
in
ATSDR
Toxicological
Profile
for
1,1­
Dichloroethene
(
not
1,2
dichloroethene).
We
would
like
to
change
this
to
2.00e­
2
mg/
kg­
day
based
on
IRIS
data
for
trans­
1,2­
dichloroethylene.

4.2
Isoquinoline
(
CAS
119653)

What
we
have
Probable
Source
What
we'd
like
to
show
Aquatic
Life,
Acute
Value
Code
=
D
[
not
on
lists]
Species
code
=
DM
[
Daphnia
magna]
Value
=
21100
Reference
provided
is
Vershueren
(
1985),
which
reports
Daphnia
pulex
24
hr
LC50:
39.9
mg/
l
It
looks
as
if
Versar
meant
the
code
to
be
LD
(
adjusted
24
hr
EC
50)
because
39.9
times
0.53
is
21.14
(
x
1000
to
convert
to
ug/
L).
We'd
like
to
change
the
species
code
to
Daphnia
pulex,
and
use
the
adjusted
24
hr
LC50
(
i.
e.,
a
factor
of
0.66
rather
than
0.53),
for
a
value
of
26334,
rounded
to
2.63e4.
7
4.3
Acrylic
Acid
(
CAS
79107)

What
we
have
What
we'd
like
to
show
Aquatic
Life,
Acute
Value
Code
=
LD4
[
not
on
lists]
Species
code
=
DM
Value
=
405000
Reference
provided
is
ACQUIRE
1990,1991.
Search
on
ECOTOX/
ACQUIRE
on
acrylic
acid
turned
up
one
reference
for
methacrylic
acid
CAS
97632
(
1999)
with
water
fleas
and
rotifers
reporting
an
EC50
level
of
250
mg/
L
Would
like
to
update
database
to:
2004
ECOTOX/
ACQUIRE
search
Code
=
EC50
Species
code
=
rotifer
value
=
250,000
ug/
L
(
all
other
references
used
formulations
in
study)

5.
Additions
to
Notes
Sheet
FCV
Final
Chronic
Value.
Frequently
the
basis
for
national
ambient
water
quality
criteria.
(
Final
residual
values
(
FRVs)
are
for
constituents
that
bioaccumulate
and
final
plant
values
(
FPVs)
are
for
plants.
The
lowest
concentration
among
the
FCV,
FRV,
and
FPV
values
is
used
as
the
Criterion
Continuous
Concentration
(
CCC)
which,
in
turn,
becomes
the
basis
for
national
ambient
water
quality
criteria.

SCV
Secondary
Chronic
Value.
Used
when
data
are
insufficient
to
develop
national
ambient
water
quality
criteria.
Method
developed
to
support
Great
Lakes
Water
Quality
Initiative,
see
60
FR
15366.
8
Table
1
Pollutants
For
Which
Versar
Did
Not
Adjust
for
Carcinogenicity
Pollutant
CAS#
Q1*
Source
Comments
Recommendation
Allyl
chloride
107051
0.0005
McGaughy,
1986
IRIS
10/
25/
04:
Designated
class
C
(
possible
human
carcinogen).
No
quantitative
estimates
of
carcinogenic
risk
derived
(
verification
date
4/
5/
89).
Region
3,
RBC
10/
04:
Not
found
Adjust
existing
Q1*
for
risk
level
of
10­
5.

Dichloropropene,
1,3­
542756
0.18
HEAST,
1997
IRIS
10/
25/
04:
Designated
as
"
likely
to
be
a
human
carcinogen."
Derived
an
oral
slope
factor
of
0.1
(
mg/
kg/
day)­
1
based
on
bladder
tumors
in
mice
(
NTP
1985).
(
Consensus
date
4/
20/
00)
Region
3,
RBC
4/
04:
References
IRIS
Revise
Q1*
to
value
provided
in
IRIS
and
adjust
for
risk
level
of
10­
5.

Mirex
\
Dechlorane
2385855
1.8
HEAST,
1992
IRIS
10/
25/
04:
Assessment
of
carcinogenicity
"
not
available
at
this
time."
(
7/
1/
93
carcinogen
assessment
under
review)
(
1/
12/
00
chemical
being
reassessed
under
IRIS
program)
Region
3,
RBC
10/
04:
No
Cancer
Slope
Factor
(
CSF)
listed.
Remove
Q1*
based
on
HEAST.

Tetrachlorvinphos
\
Gardona
\
Stirofos
961115
0.024
HEAST,
1992
IRIS
10/
25/
04:
Assessment
of
carcinogenicity
"
not
available
at
this
time."
(
Note:
Gardona
and
Stirofos
not
listed
as
synonyms.)
Region
3,
RBC
10/
04:
Not
found
Chemfinder.
com
search
did
not
find
this
CAS#.
Remove
Q1*
based
on
HEAST,
because
no
IRIS,
Region
3,
RBC,
or
HEAST
values
identified.

Tetrachlorvinphos
\
Gardona
\
Stirofos
22248799
0.024
HEAST,
1992
IRIS
10/
25/
04:
Not
found
Region
3,
RBC
4/
04:
Not
found
Name
and
CAS#
match
in
Chemfinder.
com.
Remove
Q1*
based
on
HEAST
because
no
IRIS,
Region
3,
RBC,
or
HEAST
values
identified.

Bis
(
2­
chloroisopropyl)
ether
39638329
0.07
HEAST,
1997
IRIS
10/
25/
04:
CAS
#
changed
from
39638­
32­
9
to
108­
60­
1
6/
6/
00.
Data
insufficient
to
assess
carcinogenicity.
Region
3,
RBC
10/
04:
Listed
under
CAS#
108­
60­
1.
References
HEAST
Update
CAS
#
to
108601and
adjust
existing
Q1*
for
risk
level
of
10­
5.
Table
1
Pollutants
For
Which
Versar
Did
Not
Adjust
for
Carcinogenicity
Pollutant
CAS#
Q1*
Source
Comments
Recommendation
9
Simazine
122349
0.1
HEAST,
1997
IRIS
10/
25/
04:
Assessment
of
carcinogenicity
"
not
available
at
this
time."
(
9/
1/
89
carcinogen
assessment
under
review).
Region
3,
RBC
10/
04:
References
HEAST,
but
value
listed
is
0.12
Update
Q1*
based
on
Region
3,
RBC,
2004
HEAST
value
of
0.12
and
adjust
for
risk
level
of
10­
5.

BHC,
gamma­
\
Lindane
\
HCH,
gamma­
58899
1.3
HEAST,
1997
IRIS
10/
25/
04:
Assessment
of
carcinogenicity
"
not
available
at
this
time."
Region
3,
RBC
10/
04:
References
HEAST.
Adjust
existing
Q1*
for
risk
level
of
10­
5.

Trichloropropane,
1,2,3­
96184
7
HEAST,
1997
IRIS
10/
25/
04:
Assessment
of
carcinogenicity
"
not
available
at
this
time."
(
7/
1/
92
carcinogen
assessment
under
review)
(
7/
30/
03
chemical
being
reassessed
under
IRIS
program)
Region
3,
RBC
10/
04:
References
NCEA
provisional
value
(
2.0)
Replace
HEAST,
1997
Q1*
with
Region
3,
RBC,
2004
value
of
2.0
and
adjust
for
risk
level
of
10­
5.

Ethylenethiourea
96457
0.6
HEAST,
1992
IRIS
10/
25/
04:
Assessment
of
carcinogenicity
"
not
available
at
this
time."
(
9/
1/
93
carcinogen
assessment
under
review)
Region
3,
RBC
10/
04:
References
HEAST,
but
value
listed
is
0.11.
Update
Q1*
with
Region
3,
RBC,
2004
HEAST
value
of
0.11
and
adjust
for
risk
level
of
10­
5.

Alachlor
/
Lasso
15972608
0.08
HEAST,
1992
IRIS
10/
25/
04:
Assessment
of
carcinogenicity
"
not
available
at
this
time."
Region
3,
RBC
10/
04:
References
HEAST
Adjust
existing
Q1*
for
risk
level
of
10­
5.

Tetrachloroethene
127184
0.052
HEAST,
1997
IRIS
10/
25/
04:
Assessment
of
carcinogenicity
"
not
available
at
this
time."
(
5/
1/
90
carcinogen
assessment
under
review)
(
1/
2/
98
chemical
being
reassessed
under
IRIS
program)
Region
3,
RBC
10/
04:
References
"
other,"
value
listed
is
0.54
Adjust
existing
Q1*
for
risk
level
of
10­
5.
Table
1
Pollutants
For
Which
Versar
Did
Not
Adjust
for
Carcinogenicity
Pollutant
CAS#
Q1*
Source
Comments
Recommendation
10
Atrazine
1912249
0.222
HEAST,
1997
IRIS
10/
25/
04:
Assessment
of
carcinogenicity
"
not
available
at
this
time."
(
1/
1/
91
carcinogen
assessment
under
review)
Region
3,
RBC
10/
04:
References
HEAST,
value
is
0.220
Update
Q1*
with
Region
3,
RBC,
2004
HEAST
value
of
0.22
and
adjust
for
risk
level
of
10­
5.

Chlorobenzilate
510156
0.27
HEAST,
1992
IRIS
10/
25/
04:
Assessment
of
carcinogenicity
"
not
available
at
this
time."
Region
3,
RBC
10/
04:
References
HEAST.
Adjust
existing
Q1*
for
risk
level
of
10­
5.
11
Table
2
Pollutants
For
Which
Versar
Selected
Either
the
Human
Health
or
Aquatic
Value
(
But
Had
Data
for
Both)

Pollutant
CASNU
Human
Health
Aquatic
Value
Comments
1
Recommendations
Barium
7440393
WO:
100
OO:
NA
FA:
410,000
FC:
2,810
SWA:
NA
SWC:
NA
NRWQC
2002:
Same
as
WO
in
ERG
TWF
database,
but
EPA
notes
that
barium
"
may
warrant
major
reassessment."
Human
health
values
predate
1980
methodology.
AQUIRE:
listed
as
source
of
AV
in
TWF
database.
WO:
Delete,
EPA
notes
that
major
reassessment
is
needed.

Iron
7439896
WO:
300
OO:
NA
FA:
NA
FC:
1,000
SWA:
33,000
SWC:
3,300
NRWQC
2002:
Same
as
HH
and
AV­
FC
in
TWF
database,
but
EPA
notes
that
iron
"
may
warrant
major
reassessment."
AQUIRE:
listed
as
source
of
AV­
SWA
in
TWF
database.
WO:
Delete,
EPA
notes
that
major
reassessment
is
needed.

Dichlorophenol,
2,6­
87650
WO:
0.2
OO:
NA
FA:
3,240
FC:
324
SWA:
19,100
SWC:
955
NRWQC
2002:
Human
Health
value
is
listed
for
organoleptic
effects.
NRWQC
1972:
Listed
as
source
of
AV­
FC
and
SWC
in
TWF
database.
AQUIRE:
Listed
as
source
of
AV­
FA
in
TWF
database.
Other:
Independent
review
listed
as
source
of
AV­
SWA.
WO:
Delete,
Organoleptic
effects
are
not
used
to
set
toxicity
values.
FC/
SWC:
Data
source
is
outdated
(
more
than
30
years
old).
SWA:
Discuss
EPA
confidence
in
source
and
act
accordingly.

Ethoprophos
13194484
WO:
6.12
OO:
14.7
FA:
NA
FC:
NA
SWA:
6.3
SWC:
0.063
NRWQC
2002:
Not
found.
NRWQC
1972:
Listed
as
source
of
AV­
SWC
in
TWF
database.
EPA
1987
(
600/
8­
87/
017):
Listed
as
source
of
AVSWA
in
TWF
database.
WO/
OO:
No
sources
listed.
Delete
values.
SWA:
Data
source
is
outdated
(
more
than
30
years
old).
SWC:
Discuss
EPA
confidence
in
source
and
act
accordingly.
Table
2
Pollutants
For
Which
Versar
Selected
Either
the
Human
Health
or
Aquatic
Value
(
But
Had
Data
for
Both)

Pollutant
CASNU
Human
Health
Aquatic
Value
Comments
1
Recommendations
12
Ethylphenol,
p­
123079
WO:
10
OO:
NA
FA:
10,400
FC:
1,040
SWA:
NA
SWC:
NA
NRWQC
2002:
Not
listed.
NRWQC
1972:
Listed
as
source
of
FC
in
TWF
database,
with
application
of
uncertainty
factor
of
10.
Verschueren,
1983:
Listed
as
source
of
WO
in
ERG
TWF
database.
Duluth
Toxicological
Database
(
EPA)
(
now
ASTER):
Listed
as
source
of
FA
in
TWF
database.
WO:
Data
sources
are
outdated
(
more
than
30
years
old).

AQUIRE
Aquatic
Information
Retrieval
Database
(
incorporated
into
ECOTOX
database
in
1995)
FA
Freshwater,
acute
FC
Freshwater,
chronic
NRWQC
National
Recommended
Water
Quality
Criteria
OO
Human
health,
organism
only
SWA
Salt
water,
acute
SWC
Salt
water,
chronic
WO
Human
health,
water
and
organism
13
Table
3
Pollutants
For
Which
Versar
Had
The
Data
to
Calculate
TWFs
But
Did
Not
Do
So
Pollutant
CASNU
HH
AV
ERG
TWF
Comments
1
Nitrate
14797558
WO:
10,000
OO:
NA
FA:
NA
FC:
NA
SWA:
NA
SWC:
NA
5.60E­
04
NRWQC
2002:
Same
as
WO
in
TWF
database.
AWQC
1980:
Listed
as
source
of
WO
in
TWF
database.

Nitroso­
Nmethylurea
N­
684935
WO:
0.00269
OO:
NA
FA:
NA
FC:
NA
SWA:
NA
SWC:
NA
2.08E+
04
No
source
listed
for
WO
in
TWF
database
Indole
120729
WO:
500
OO:
NA
FA:
NA
FC:
NA
SWA:
NA
SWC:
NA
1.12E­
02
Verschueren,
1983:
Listed
as
source
of
WO
in
TWF
database.

Ethylphenol,
o­
90006
WO:
30
OO:
NA
FA:
NA
FC:
NA
SWA:
NA
SWC:
NA
1.87E­
01
Verschueren,
1983:
Listed
as
source
of
WO
in
TWF
database.

Dibenzo(
a,
h)­
pyrene
189640
WO:
0.001
OO:
NA
FA:
NA
FC:
NA
SWA:
NA
SWC:
NA
5.60E+
03
Neely,
1983:
Listed
as
source
of
WO
in
TWF
database.

Niacide
15339363
WO:
NA
OO:
NA
FA:
NA
FC:
NA
SWA:
1,000
SWC:
50
1.12E­
01
NRWQC
1972:
Listed
as
source
of
FC
in
TWF
database,
with
application
of
uncertainty
factor
of
10
(
EPA
1991
Technical
Support
document)
EPA
1987
(
600/
8­
87/
017):
Listed
as
source
of
AV­
SWA
in
TWF
database.

Ethyl
phosphate
78400
WO:
NA
OO:
NA
FA:
NA
FC:
NA
SWA:
950,000
SWC:
47,500
1.18E­
04
No
source
listed
for
AV­
SWC
in
TWF
database.
Other:
Independent
review
listed
as
source
of
AV­
SWA.

Chloroaniline,
m­
108429
WO:
NA
OO:
NA
FA:
NA
FC:
NA
SWA:
25,000
SWC:
1,250
4.48E­
03
NRWQC
1972:
Listed
as
source
of
AV­
SWC
in
TWF
database,
with
"
acute
X
application
factor."
Other:
Independent
review
listed
as
source
of
AV­
SWA.
Table
3
Pollutants
For
Which
Versar
Had
The
Data
to
Calculate
TWFs
But
Did
Not
Do
So
Pollutant
CASNU
HH
AV
ERG
TWF
Comments
1
14
Naphthol,
2­
135193
WO:
OO:
FA:
FC:
SWA:
2,500
SWC:
125
4.48E­
02
NRWQC
1972:
Listed
as
source
of
AV­
SWC
in
TWF
database,
with
"
acute
X
application
factor."
Other:
Independent
review
listed
as
source
of
AV­
SWA.

Propylbenzene,
n­
103651
WO:
NA
OO:
NA
FA:
NA
FC:
NA
SWA:
9,1400
SWC:
914
6.13E­
03
NRWQC
1972:
Listed
as
source
of
AV­
SWC
in
TWF
database,
with
"
acute
X
application
factor."
Other:
Independent
review
listed
as
source
of
AV­
SWA.

Diisobutyl
phthalate
84695
WO:
OO:
FA:
FC:
SWA:
3,000
SWC:
30
1.87E­
01
NRWQC
1972:
Listed
as
source
of
AV­
SWC
in
TWF
database,
with
"
acute
X
application
factor."
Other:
Independent
review
listed
as
source
of
AV­
SWA.

Dinonyl
phthalate
84764
WO:
NA
OO:
NA
FA:
NA
FC:
NA
SWA:
300,000
SWC:
3,000
1.87E­
03
No
source
listed
for
AV­
SWC
in
TWF
database.
NRWQC
1972:
Listed
as
source
of
AV­
SWA
in
TWF
database,
with
"
acute
X
application
factor."

Tetramethylbenzene
1,2,4,5­
95932
WO:
NA
OO:
NA
FA:
NA
FC:
NA
SWA:
2,100
SWC:
21
2.67E­
01
No
source
listed
for
AV­
SWC
in
TWF
database.
NRWQC
1972:
Listed
as
source
of
AV­
SWA
in
TWF
database,
with
"
acute
X
application
factor."

Trimethylbenzene
1,3,5­
108678
WO:
OO:
FA:
FC:
SWA:
4,300
SWC:
43
1.30E­
01
No
source
listed
for
AV­
SWC
in
TWF
database.
NRWQC
1972:
Listed
as
source
of
AV­
SWA
in
TWF
database,
with
"
acute
X
application
factor."

Undecanol,
1­
112425
WO:
NA
OO:
NA
FA:
NA
FC:
NA
SWA:
4,000
SWC:
40
1.40E­
01
No
source
listed
for
AV­
SWC
in
TWF
database.
NRWQC
1972:
Listed
as
source
of
AV­
SWA
in
TWF
database,
with
"
acute
X
application
factor."

Dodecanol
112538
WO:
NA
OO:
NA
FA:
NA
FC:
NA
SWA:
900
SWC:
9
6.22E­
01
No
source
listed
for
AV­
SWC
in
TWF
database.
NRWQC
1972:
Listed
as
source
of
AV­
SWA
in
TWF
database,
with
"
acute
X
application
factor."
Table
3
Pollutants
For
Which
Versar
Had
The
Data
to
Calculate
TWFs
But
Did
Not
Do
So
Pollutant
CASNU
HH
AV
ERG
TWF
Comments
1
15
Dimethylnaphthalene
2,6­
581420
WO:
NA
OO:
NA
FA:
NA
FC:
NA
SWA:
2,600
SWC:
26
2.15E­
01
No
source
listed
for
AV­
SWC
in
TWF
database.
NRWQC
1972:
Listed
as
source
of
AV­
SWA
in
TWF
database,
with
"
acute
X
application
factor."

Dimethyl
naphthalene
28804888
WO:
NA
OO:
NA
FA:
NA
FC:
NA
SWA:
2,600
SWC:
26
2.15E­
01
No
source
listed
for
AV­
SWC
in
TWF
database.
NRWQC
1972:
Listed
as
source
of
AV­
SWA
in
TWF
database,
with
"
acute
X
application
factor."

AWQC
Ambient
Water
Quality
Criteria
FA
Freshwater,
acute
FC
Freshwater,
chronic
NRWQC
National
Recommended
Water
Quality
Criteria
OO
Human
health,
organism
only
SWA
Salt
water,
acute
SWC
Salt
water,
chronic
WO
Human
health,
water
and
organism
1
Only
Nitrate
was
listed
in
NRWQC,
2002
document.
16
Table
4
Freshwater
Aquatic
Acute
Chemical
Problematic
Code
What
We
Will
do
Hydrochloric
acid
Missing
species
Reference
is
to
IRIS
data
which
were
removed
in
1997.
Need
to
identify
new
data
source.
For
now,
leave
unchanged.

Fluoride
Missing
species
Zang,
R
and
E.
Zhang.
1982.
"
Toxicity
of
Fluoride
to
Fishes"
does
not
identify
type
of
fish
in
article
title.
Have
not
yet
located
article
based
on
citation.
For
now,
complete
with
"
fish."

Furfuyl
alcohol
Missing
human
health
Vershuren
1983
lists
"
toxic."
We
will
complete
with
this
entry.

Hydrogen
cyanide
Missing
species
rat.
We
will
complete
with
this
entry.

Thiocyanate
Missing
species
rainbow
trout.
We
will
complete
with
this
entry.

Methylcyclohexane
Missing
species
golden
shriner.
We
will
complete
with
this
entry.

1,1'­
oxybis­
2­
propanol
Missing
human
health
LC50.
We
will
complete
with
this
entry.

Nitrosomorpholine,
NMissing
human
health
LC50.
We
will
complete
with
this
entry.
17
Table
5
Freshwater
Aquatic
Chronic
Chemical
Problematic
Code
What
We
Will
do
Total
Petroleum
Hydrocarbons
Toxicity
code
=
@
AAC
Species
code
=
FF
Toxicity
code
should
have
been
@
AAB.
See
change
described
in
Section
2.1.
FF
=
finfish.
We
will
complete
with
this
entry.
Note:
need
to
transfer
corrections
to
Freshwater
Acute
sheet
as
well.

Several
Missing
species
Toxicity
test
is
listed
as
ECGR:
Lowest
Reported
96
hr
EC
for
green
algae
(
growth
effect).
Complete
species
with
"
green
algae."

Dichloropropene,
cis­
1,3­
Species
code
=
LC
Toxicity
code
is
LM:
lowest
reported
MATC
value.
Toxicity
code
LC
is
"
lowest
reported
chronic
value."
Reference
is
EPA
1980
and
none
of
them
list
species.
We
assume
that
the
species
code
was
the
toxicity
code
entered
into
the
wrong
column.
Based
on
the
reference
cited,
we
will
complete
the
species
entry
as
"
None
listed,"
see
Section
2.3.

Endrin
ketone
Toxicity
code
=
FCV
Probably
"
final
chronic
value"
but
just
not
on
any
of
the
printed
Versar
lists.
Reference
is
to
EPA,
1980.
We
will
change
entry
to
"
EPA
critieria"
for
consistency
with
all
other
aquatic
toxicity
values
taken
from
EPA,
1980.

Ammonium
as
perchlorate
Toxicity
code
=
SCV
Reference
=
314
Probably
"
secondary
chronic
value"
but
just
not
on
any
of
the
Versar
lists.
We
will
complete
the
entry
with
"
secondary
chronic
value."
Versar
Reference
314
is
not
on
any
of
the
lists.
We
have
an
e­
mail
from
Versar
that
it
is
EPA,
Preliminary
Data
Summary
Airport
Deicing
Operations.
We
examined
that
document
and
could
not
find
the
data
for
ammonium
as
perchlorate.
Another
reference
not
on
any
of
the
Versar
lists
is
311.
Versar
provided
an
e­
mail
with
the
information
that
311
is
USEPA.
1998.
Perchlorate
Environmental
Contamination:
Toxicological
Review
and
Risk
Characterization
Based
on
Emerging
Information.
Review
Draft.
Reference
311
provides
the
secondary
chronic
value
of
600
ug/
L
for
perchlorate.
We
will
insert
the
correct
reference.
18
Table
6
Saltwater
Aquatic
Acute
Chemical
Problematic
Code
What
We
Will
do
Arsenic
(
V)
Toxicity
code
=
MS
Species
code
=
L9
Codes
are
reversed.
We
will
set
toxicity
code
=
L9
and
species
code
to
MS.

Dibromo­
3
chloropropane
1,2
Toxicity
code
=
A4
Correct
to
LA4.

Aircraft
deicing
fluids
(
assigned
CAS
numbers
103­
106)
Reference
=
311
Correct
to
314
(
PDS
Aircraft
Deicing)

BHC,
delta­
Species
=
EM
Not
on
Versar
lists.
Complete
with
"
Pearlspot"
[
Etroplus
maculatus].

Napthalene
Species
=
OG
Not
on
Versar
lists.
Complete
with
"
Pink
Salmon"
[
Oncorhynchus
gorbuscha].

Trichloromethane
Missing
species
Brine
shrimp.
We
will
complete
with
this
entry.
19
Table
7
Saltwater
Aquatic
Chronic
Chemical
Problematic
Code
What
We
Will
do
Sodium
Nitrate
Species
code
=
JP
Complete
with
"
Jumbo
tiger
prawn"
[
penaeus
monodon]

Benzene
Species
code
=
PH
Problem.
Reference
is
1,
which
usually
means
that
the
toxicity
code
=
EPA
criteria
and
species
=
none
listed.
PH
probably
stands
for
Pacific
herring,
but
I
could
not
line
up
a
single
entry
in
ECOTOX
with
the
700
value.
Look
for
updated
reference.

Fluoranthene
Toxicity
code
=
LV
Problem.
Reference
is
1,
which
usually
means
that
the
toxicity
code
=
EPA
criteria.
Species
is
listed
as
"
mysid
shrimp."
Look
for
updated
reference.

Di­
n­
butyl
phthalate
Toxicity
code
=
EC50
The
value
is
an
EC50
value
but
for
a
96
hour
test.
Complete
with
"
lowest
reported
96
hour
EC50
test."

Napthalene
Species
=
OG
Not
on
Versar
lists.
Complete
with
"
Pink
Salmon"
[
Oncorhynchus
gorbuscha].

Sodium
Nitrate
Missing
species
Jumbo
tiger
prawn.
We
complete
with
this
entry.
Table
8
Bioconcentration
Factors
20
Chemical
Problematic
Code
What
We
Will
do
o,
p'­
DDD;
2,4'­
DDD
No
source
listed.
Update
and
document.

DDT
(
from
GLI)
Find
proper
Great
Lakes
Initiative
citation.

m,
p'­
DDD;
3,4'­
DDD
Update
and
document.

Chlordane,
technical
Update
from
EPA­
822­
R­
02­
047
(
2002
AWQC)

o,
p'­
DDE;
2,4'­
DDE
Update
and
document.

Heptachlorodibenzofuran
1,2,3,4,7,8,9­
Replace
data
for
dioxin
cogeners
with
updated
data
from
Lynn
Zipf
memo.

Hexachlorodibenzo­
pdioxin
1,2,3,7,8,9­
Replace
data
for
dioxin
cogeners
with
updated
data
from
Lynn
Zipf
memo.

Methylnaphthalene,
1­
Missing
species
Reference
is
Verschueren,
1983.
Complete
with
"
Coho
salmon
and
starry
flounder"

Multiple
entries
Species
code
=
E,
EP,
ES,
or
M
Not
on
Versar
lists.
Most
of
the
references
associated
with
these
species
values
are:
(
1)
Lyman
WJ,
Reehl
WF,
Rosenblatt
DH.
1981.
Handbook
of
chemical
property
estimation
methods
­
environmental
behavior
of
organic
compounds.
New
York,
NY:
McGraw­
Hill
Book
Company.
960
pp.
(
reported
or
estimated
using
methods
outlined;
(
2)
Arthur
D.
Little.
1986.
Bioaccumulation
Study;
and
(
3)
USEPA.
1989.
U.
S.
Environmental
Protection
Agency.
Computer
data
base
of
physical/
chemical
properties
for
SARA
313
chemicals.
Washington,
DC:
Office
of
Toxic
Substances,
Exposure
Evaluation
Division,
U.
S.
Environmental
Protection
Agency.
(
Used
in
the
Toxic
Chemical
Release
Inventory
Risk
Screening
Guide)
EPA
560/
2­
89­
002.
Given
the
dates
of
the
references,
we
recommend
that
these
go
on
a
list
of
items
to
be
updated.

Pentachlorobenzene
Reference
=
SCM
Need
to
ask
Versar.

Allethrin
missing
species
missing
test
duration
from
QSAR.
Complete
all
species
with
"
fathead
minnow"
and
all
durations
with
"
2
to
304."
Docosane,
n­
Table
8
Bioconcentration
Factors
Chemical
Problematic
Code
What
We
Will
do
21
Eicosane,
n­

Permethrin
II
Permethrin
I
Pyrethrin
I
Pyrethrin
II
Resmethrin
Sumithrin
Tetracosane,
 
n
Tetramethrin
\
Neo­
pynamin