Document ID: FDA-2007-D-0369-0001
Agency: fda
Document Type: Notice
Title: Draft Guidances for Industry Describing Product-Specific Bioequivalence Recommendations; Availability
Posted Date: 2007-06-06T04:00Z

<!DOCTYPE HTML PUBLIC "-//-//W3C//DTD HTML 3.2//EN">
<HTML>
<HEAD>
<META name="generator" content="PDFCreactiveX HTML Export">
<META name="creation-date" content="07/04/2008 07:09:35 ">
<TITLE></TITLE>
<SCRIPT LANGUAGE="JavaScript1.2"> var agt=navigator.userAgent.toLowerCase();if ( (parseInt(navigator.appVersion)>=4) &&(agt.indexOf('mozilla')!=-1) && (agt.indexOf('spoofer')==-1)&& (agt.indexOf('compatible') == -1) ){msie = false;} else if ( (parseInt(navigator.appVersion)>=4) &&(agt.indexOf('msie') != -1) ) {msie = true;	} page=0;</SCRIPT>
</HEAD>
<BODY bgcolor="#ffffff" text="#000000" topmargin=0 leftmargin=0 marginheight=0 marginwidth=0 >
<SPAN STYLE="color:#000000;position:absolute;left:33.95pt;top:44.55pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:34.20pt;top:81.50pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.95pt;top:118.15pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:81.10pt;top:117.05pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:102.60pt;top:118.25pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:34.20pt;top:153.25pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:34.45pt;top:179.40pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.50pt;top:218.15pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:85.45pt;top:215.85pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.50pt;top:249.00pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:80.65pt;top:246.70pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.50pt;top:308.25pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:94.45pt;top:305.95pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.50pt;top:331.75pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.50pt;top:357.90pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:53.75pt;top:359.80pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:78.70pt;top:357.95pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.95pt;top:383.75pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.25pt;top:409.05pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.25pt;top:435.20pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.50pt;top:461.25pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.50pt;top:487.15pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.00pt;top:512.50pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.50pt;top:538.15pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.25pt;top:564.45pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.25pt;top:590.35pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.25pt;top:615.95pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.75pt;top:641.25pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.00pt;top:667.65pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.75pt;top:693.95pt;z-index:3;"></SPAN>
<SPAN STYLE="position:absolute;left:71.76pt;top:791.00pt"> </SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:262.70pt;top:808.15pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.10pt;top:834.85pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:75.85pt;top:831.80pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.10pt;top:857.45pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:62.75pt;top:859.60pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:87.85pt;top:857.50pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.40pt;top:884.25pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.15pt;top:915.75pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:104.15pt;top:913.45pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.15pt;top:938.65pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:31.95pt;top:964.65pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.20pt;top:990.70pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:31.95pt;top:1016.25pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:31.70pt;top:1041.45pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:31.65pt;top:1067.25pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:241.90pt;top:1067.85pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:266.05pt;top:1067.25pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:31.90pt;top:1093.30pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:31.45pt;top:1120.55pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:202.20pt;top:1118.25pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:31.70pt;top:1143.35pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:31.70pt;top:1175.05pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:241.45pt;top:1172.45pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:30.95pt;top:1198.30pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:31.20pt;top:1223.20pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:30.70pt;top:1254.50pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:30.50pt;top:1281.60pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:42.85pt;top:1281.15pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:56.50pt;top:1309.30pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:30.75pt;top:1334.25pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:30.50pt;top:1359.60pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:29.75pt;top:1385.40pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:30.00pt;top:1411.20pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:29.75pt;top:1436.40pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:29.75pt;top:1461.95pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:29.75pt;top:1488.00pt;z-index:3;"></SPAN>
<SPAN STYLE="position:absolute;left:71.76pt;top:1582.00pt"> </SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:261.35pt;top:1599.40pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:31.45pt;top:1623.85pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:31.45pt;top:1649.10pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:444.95pt;top:1650.85pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:462.50pt;top:1649.30pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:31.45pt;top:1675.70pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:57.10pt;top:1704.50pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:31.45pt;top:1730.20pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:31.20pt;top:1755.90pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:69.60pt;top:1785.15pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:30.95pt;top:1811.30pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:30.95pt;top:1836.80pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:30.70pt;top:1862.45pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:30.50pt;top:1889.05pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:30.25pt;top:1914.75pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:30.70pt;top:1940.20pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:57.10pt;top:1940.95pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:264.95pt;top:1940.20pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:30.00pt;top:1965.60pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:68.15pt;top:1994.65pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:29.75pt;top:2020.35pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:29.25pt;top:2045.30pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:68.15pt;top:2073.15pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:29.50pt;top:2099.80pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:29.00pt;top:2125.70pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:28.80pt;top:2151.15pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:67.45pt;top:2179.70pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:28.55pt;top:2205.85pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:66.70pt;top:2234.65pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:27.85pt;top:2260.35pt;z-index:3;"></SPAN>
<SPAN STYLE="position:absolute;left:71.76pt;top:2372.00pt"> </SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:59.50pt;top:2411.45pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.35pt;top:2437.15pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.35pt;top:2462.35pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.35pt;top:2485.60pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.60pt;top:2500.00pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:59.05pt;top:2524.95pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.35pt;top:2550.20pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.60pt;top:2566.35pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.35pt;top:2575.75pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.35pt;top:2583.65pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.35pt;top:2591.60pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.35pt;top:2599.50pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.10pt;top:2607.45pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.35pt;top:2615.10pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.10pt;top:2623.05pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.35pt;top:2630.95pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.35pt;top:2638.40pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.10pt;top:2646.05pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.35pt;top:2653.75pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.35pt;top:2661.45pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.35pt;top:2669.10pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.90pt;top:2676.80pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.10pt;top:2684.45pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.10pt;top:2692.40pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.90pt;top:2700.30pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.60pt;top:2712.20pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.35pt;top:2721.90pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.35pt;top:2729.60pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.35pt;top:2737.05pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.35pt;top:2744.70pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.35pt;top:2752.15pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.10pt;top:2763.75pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.10pt;top:2773.05pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.90pt;top:2780.70pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.90pt;top:2788.40pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.90pt;top:2796.30pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.90pt;top:2804.00pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.65pt;top:2811.65pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.65pt;top:2819.60pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.65pt;top:2827.25pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.65pt;top:2834.95pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.65pt;top:2843.10pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.40pt;top:2850.05pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.40pt;top:2857.50pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.40pt;top:2865.20pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.40pt;top:2872.85pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.90pt;top:2884.55pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.65pt;top:2894.00pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.65pt;top:2901.90pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.65pt;top:2909.60pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.65pt;top:2917.50pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.65pt;top:2925.45pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.65pt;top:2933.10pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.15pt;top:2941.05pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.15pt;top:2948.70pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.15pt;top:2956.40pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:149.75pt;top:2959.45pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.15pt;top:2963.85pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.15pt;top:2971.50pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.15pt;top:2979.20pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.15pt;top:2986.85pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.15pt;top:2994.55pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:31.90pt;top:3002.45pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:31.90pt;top:3010.15pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:31.90pt;top:3018.05pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:31.90pt;top:3026.00pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.15pt;top:3038.10pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:31.90pt;top:3047.85pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:31.90pt;top:3055.75pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:31.90pt;top:3063.65pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:31.70pt;top:3071.10pt;z-index:3;"></SPAN>
<SPAN STYLE="position:absolute;left:71.76pt;top:3162.00pt"> </SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:35.75pt;top:3201.70pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:35.50pt;top:3209.60pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:35.50pt;top:3217.75pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:35.50pt;top:3225.45pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:35.75pt;top:3233.35pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:35.50pt;top:3241.05pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:35.75pt;top:3253.15pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:35.50pt;top:3262.40pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:35.50pt;top:3270.10pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:35.50pt;top:3277.75pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:35.50pt;top:3285.20pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:35.50pt;top:3293.15pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:35.30pt;top:3300.80pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:35.30pt;top:3308.75pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:35.30pt;top:3316.65pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:35.30pt;top:3324.55pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:35.05pt;top:3336.60pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:35.05pt;top:3346.40pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:35.05pt;top:3354.10pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:35.05pt;top:3361.75pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:35.05pt;top:3369.45pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:34.80pt;top:3377.15pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:35.05pt;top:3384.80pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:34.80pt;top:3392.50pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:34.80pt;top:3400.40pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:35.05pt;top:3412.20pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:35.05pt;top:3422.00pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:34.80pt;top:3429.70pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:34.80pt;top:3437.60pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:34.80pt;top:3445.30pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:34.80pt;top:3452.95pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:34.80pt;top:3460.90pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:34.80pt;top:3472.75pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:35.05pt;top:3481.75pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:34.80pt;top:3489.45pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:34.80pt;top:3497.15pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:34.80pt;top:3504.80pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:34.80pt;top:3512.50pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:34.80pt;top:3520.15pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:34.80pt;top:3528.35pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:34.55pt;top:3540.15pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:34.30pt;top:3549.70pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:34.30pt;top:3557.60pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:34.10pt;top:3565.30pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:34.10pt;top:3572.95pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:34.10pt;top:3580.40pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:34.30pt;top:3588.10pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:34.30pt;top:3599.85pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:34.10pt;top:3609.45pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:34.10pt;top:3617.00pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.85pt;top:3625.30pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.85pt;top:3632.95pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.85pt;top:3640.65pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.60pt;top:3648.55pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.60pt;top:3656.50pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.60pt;top:3664.15pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.60pt;top:3671.85pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.35pt;top:3679.55pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.35pt;top:3687.20pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.35pt;top:3695.15pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.35pt;top:3702.80pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.60pt;top:3710.50pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.35pt;top:3718.40pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.35pt;top:3730.45pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.35pt;top:3740.50pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.10pt;top:3748.40pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.10pt;top:3756.35pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.10pt;top:3764.00pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.90pt;top:3775.90pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.65pt;top:3785.35pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.65pt;top:3793.05pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.40pt;top:3800.95pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.40pt;top:3808.65pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.15pt;top:3816.55pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.15pt;top:3824.25pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.40pt;top:3832.40pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.90pt;top:3844.45pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.40pt;top:3854.50pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.40pt;top:3862.40pt;z-index:3;"></SPAN>
<SPAN STYLE="position:absolute;left:71.76pt;top:3952.00pt"> </SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:34.10pt;top:3993.65pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:34.10pt;top:4002.65pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.60pt;top:4015.15pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.35pt;top:4025.45pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.35pt;top:4034.10pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.85pt;top:4045.95pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.85pt;top:4057.25pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.85pt;top:4065.90pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.85pt;top:4074.20pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.85pt;top:4082.60pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.85pt;top:4091.00pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.60pt;top:4099.15pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.60pt;top:4107.65pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.60pt;top:4116.05pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.35pt;top:4124.45pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.60pt;top:4133.35pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.60pt;top:4142.25pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.60pt;top:4150.75pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.35pt;top:4163.40pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.10pt;top:4173.80pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.10pt;top:4182.30pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.10pt;top:4190.70pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.10pt;top:4199.10pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.90pt;top:4207.25pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.90pt;top:4215.80pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.90pt;top:4224.20pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.10pt;top:4232.85pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.90pt;top:4245.25pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.90pt;top:4256.00pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.65pt;top:4264.40pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.65pt;top:4272.80pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.65pt;top:4281.20pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.65pt;top:4289.70pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.65pt;top:4297.65pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.40pt;top:4306.05pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.65pt;top:4314.20pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.65pt;top:4322.35pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.65pt;top:4330.65pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.65pt;top:4339.05pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.65pt;top:4347.45pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.40pt;top:4355.85pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.40pt;top:4364.35pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.40pt;top:4372.50pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.15pt;top:4380.45pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.40pt;top:4389.85pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.15pt;top:4402.85pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.15pt;top:4411.25pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.40pt;top:4419.45pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.40pt;top:4427.35pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.40pt;top:4435.30pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.15pt;top:4444.05pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:31.90pt;top:4453.15pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:31.90pt;top:4466.95pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:31.90pt;top:4475.10pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:31.90pt;top:4483.50pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:31.70pt;top:4491.65pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:57.50pt;top:4522.65pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:30.95pt;top:4547.75pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:30.95pt;top:4574.25pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:31.20pt;top:4599.70pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:285.50pt;top:4600.30pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:30.95pt;top:4625.05pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:30.95pt;top:4651.05pt;z-index:3;"></SPAN>
<SPAN STYLE="position:absolute;left:71.76pt;top:4744.00pt"> </SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:263.90pt;top:4759.45pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:58.70pt;top:4784.00pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.65pt;top:4809.30pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:209.40pt;top:4811.30pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:231.35pt;top:4809.30pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:260.30pt;top:4811.30pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:309.85pt;top:4809.30pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.40pt;top:4834.85pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.85pt;top:4861.15pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.65pt;top:4886.60pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.40pt;top:4911.90pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.45pt;top:4937.70pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:31.90pt;top:4961.40pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:54.10pt;top:4961.50pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:57.50pt;top:4987.50pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:31.45pt;top:5014.85pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:102.70pt;top:5012.85pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:31.90pt;top:5038.15pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:31.65pt;top:5063.85pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:30.90pt;top:5089.65pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:31.35pt;top:5114.70pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:30.90pt;top:5139.65pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:227.05pt;top:5140.90pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:237.60pt;top:5139.65pt;z-index:3;"></SPAN>
<SPAN STYLE="position:absolute;left:71.76pt;top:5535.00pt"> </SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:263.10pt;top:5550.60pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.30pt;top:5575.15pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:58.90pt;top:5600.50pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.30pt;top:5626.05pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:484.90pt;top:5626.05pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.85pt;top:5686.50pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:132.55pt;top:5664.80pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:157.40pt;top:5681.70pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:72.45pt;top:5701.15pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:96.90pt;top:5701.45pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:120.30pt;top:5701.25pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:72.45pt;top:5778.80pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:131.35pt;top:5778.40pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:230.35pt;top:5778.80pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:33.30pt;top:5810.95pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:82.30pt;top:5812.50pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:130.65pt;top:5810.85pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:162.45pt;top:5812.50pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:215.70pt;top:5812.00pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:32.60pt;top:5840.00pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:56.95pt;top:5890.25pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:60.30pt;top:5900.00pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:91.15pt;top:5899.00pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:107.00pt;top:5900.65pt;z-index:3;"></SPAN>
<SPAN STYLE="position:absolute;left:71.76pt;top:6327.00pt"> </SPAN>
</BODY>
</HTML>