Document ID: FDA-2008-P-0242-0009
Agency: fda
Document Type: Supporting & Related Material
Title: 
Posted Date: 2008-05-24T04:00Z

<!DOCTYPE HTML PUBLIC "-//-//W3C//DTD HTML 3.2//EN">
<HTML>
<HEAD>
<META name="generator" content="PDFCreactiveX HTML Export">
<META name="creation-date" content="24/05/2008 07:00:27 ">
<TITLE></TITLE>
<SCRIPT LANGUAGE="JavaScript1.2"> var agt=navigator.userAgent.toLowerCase();if ( (parseInt(navigator.appVersion)>=4) &&(agt.indexOf('mozilla')!=-1) && (agt.indexOf('spoofer')==-1)&& (agt.indexOf('compatible') == -1) ){msie = false;} else if ( (parseInt(navigator.appVersion)>=4) &&(agt.indexOf('msie') != -1) ) {msie = true;	} page=0;</SCRIPT>
</HEAD>
<BODY bgcolor="#ffffff" text="#000000" topmargin=0 leftmargin=0 marginheight=0 marginwidth=0 >
<SPAN STYLE="color:#000000;background-color:#ffffff;position:absolute;left:0.00pt;top:-1.00pt;z-index:2;"><IMG WIDTH=1696 HEIGHT=2200 style="width:610pt;height:792pt;" SRC="outputfile1794148284.htm_files\outputfile1794148284_p0.png"></SPAN>
<SPAN STYLE="position:absolute;left:71.76pt;top:792.00pt"> </SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:64.90pt;top:812.95pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:503.65pt;top:810.30pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:332.15pt;top:873.65pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:351.95pt;top:872.65pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:406.80pt;top:860.90pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:479.30pt;top:873.90pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:490.45pt;top:866.60pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:332.15pt;top:876.85pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:360.50pt;top:876.10pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:393.50pt;top:877.10pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:537.70pt;top:880.70pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:274.70pt;top:902.25pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:437.75pt;top:903.05pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:275.15pt;top:927.40pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:67.10pt;top:1009.15pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:122.15pt;top:1009.90pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:133.55pt;top:1009.15pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:90.10pt;top:1035.15pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:121.45pt;top:1035.65pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:138.35pt;top:1035.25pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:303.85pt;top:1035.65pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:319.80pt;top:1035.15pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:530.30pt;top:1035.65pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:546.25pt;top:1035.35pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:90.35pt;top:1047.75pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:197.30pt;top:1048.25pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:213.25pt;top:1047.60pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:251.40pt;top:1047.80pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:256.80pt;top:1047.75pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:278.75pt;top:1048.25pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:294.95pt;top:1047.75pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:87.85pt;top:1087.35pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:459.00pt;top:1087.35pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:540.95pt;top:1081.80pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:96.85pt;top:1118.20pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:96.10pt;top:1132.05pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:126.10pt;top:1132.55pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:227.30pt;top:1133.40pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:277.10pt;top:1132.55pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:96.60pt;top:1160.90pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:257.75pt;top:1189.20pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:257.75pt;top:1201.70pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:404.65pt;top:1201.70pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:99.00pt;top:1214.55pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:309.50pt;top:1213.95pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:369.10pt;top:1214.55pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:515.75pt;top:1214.55pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:99.00pt;top:1229.70pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:257.50pt;top:1229.70pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:404.40pt;top:1229.70pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:515.50pt;top:1229.70pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:99.25pt;top:1243.00pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:309.70pt;top:1242.55pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:404.90pt;top:1242.55pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:516.00pt;top:1242.55pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:309.25pt;top:1255.00pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:404.65pt;top:1255.25pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:516.00pt;top:1255.25pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:309.95pt;top:1267.95pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:405.10pt;top:1267.95pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:461.90pt;top:1268.45pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:473.75pt;top:1267.95pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:309.95pt;top:1281.15pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:310.20pt;top:1294.00pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:405.10pt;top:1294.00pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:309.70pt;top:1308.90pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:99.70pt;top:1322.95pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:99.70pt;top:1335.55pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:99.95pt;top:1351.50pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:258.45pt;top:1350.50pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:258.50pt;top:1363.50pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:99.25pt;top:1379.45pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:258.00pt;top:1392.30pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:258.70pt;top:1407.75pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:258.95pt;top:1423.75pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:258.70pt;top:1439.45pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:258.50pt;top:1451.95pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:99.95pt;top:1467.30pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:258.50pt;top:1480.00pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:99.70pt;top:1495.50pt;z-index:3;"></SPAN>
<SPAN STYLE="position:absolute;left:71.76pt;top:1585.00pt"> </SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:66.10pt;top:1596.50pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:505.45pt;top:1595.55pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:257.40pt;top:1658.05pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:257.65pt;top:1674.00pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:257.65pt;top:1689.40pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:256.90pt;top:1702.45pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:99.10pt;top:1718.30pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:257.40pt;top:1717.80pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:258.60pt;top:1731.55pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:369.60pt;top:1730.80pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:257.40pt;top:1743.40pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:487.10pt;top:1744.15pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:258.85pt;top:1757.10pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:329.15pt;top:1756.35pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:395.30pt;top:1757.10pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:98.90pt;top:1772.05pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:257.85pt;top:1784.80pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:327.50pt;top:1785.55pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:98.40pt;top:1800.60pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:257.65pt;top:1813.45pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:257.85pt;top:1826.40pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:99.10pt;top:1842.00pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:257.60pt;top:1842.00pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:257.65pt;top:1855.35pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:358.70pt;top:1854.60pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:257.65pt;top:1867.60pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:486.35pt;top:1868.35pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:257.90pt;top:1881.15pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:328.90pt;top:1880.40pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:394.55pt;top:1881.15pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:257.90pt;top:1896.15pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:361.20pt;top:1896.90pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:98.90pt;top:1911.85pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:257.90pt;top:1924.95pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:329.15pt;top:1925.70pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:98.65pt;top:1940.30pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:258.10pt;top:1953.40pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:258.10pt;top:1966.10pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:96.50pt;top:1994.30pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:72.00pt;top:2056.10pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:110.50pt;top:2055.50pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:374.90pt;top:2055.60pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:498.60pt;top:2056.35pt;z-index:3;"></SPAN>
<SPAN STYLE="position:absolute;left:71.76pt;top:2377.00pt"> </SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:63.35pt;top:2391.80pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:501.85pt;top:2389.40pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:69.60pt;top:2757.80pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:101.75pt;top:2755.25pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:106.55pt;top:2754.65pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:208.80pt;top:2755.95pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:379.90pt;top:2757.80pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:534.50pt;top:2765.45pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:70.30pt;top:2770.45pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:69.85pt;top:2827.60pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:69.85pt;top:2840.50pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:70.10pt;top:2853.20pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:129.10pt;top:2881.85pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:167.50pt;top:2879.55pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:172.10pt;top:2880.25pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:196.55pt;top:2879.30pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:201.10pt;top:2879.00pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:459.10pt;top:2885.60pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:129.60pt;top:2896.25pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:465.35pt;top:2888.60pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:486.95pt;top:2909.70pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:502.55pt;top:2910.80pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:519.85pt;top:2906.50pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:129.35pt;top:2909.45pt;z-index:3;"></SPAN>
<SPAN STYLE="position:absolute;left:71.76pt;top:3170.00pt"> </SPAN>
</BODY>
</HTML>