Document ID: EPA-HQ-OPP-2007-0097-0002
Agency: epa
Document Type: Supporting & Related Material
Title: 
Posted Date: 2007-06-06T04:00Z

SEQ CHAPTER \h \r 1 

April 30, 1999

MEMORANDUM

SUBJECT:	Captan (081301) Reregistration Case No. 0120.  Product and
Residue Chemistry Chapters for the Captan Reregistration Eligibility
Decision (RED). DP Barcode D255103

FROM:	Thurston Morton, Chemist

		Reregistration Branch 4 

Health Effects Division (7509C)

THRU:	Susan Hummel, Branch Senior Scientist

Reregistration Branch 4 

Health Effects Division (7509C)

TO:		David Hrdy, Chemist

Reregistration Branch 4

Health Effects Division (7509C)

Kylie Rothwell

Special Review and Reregistration Division (7508W)

Attached are the updated Product and Residue Chemistry Chapters to the
Captan RED.  This updates the Chemistry Chapter of 9/7/94 by C. Olinger.
The chapters were assembled by Dynamac Corporation (1/6/94) under
supervision of HED and addenda since RED production,  incorporated
within.  The data assessment has undergone secondary review in the
branch and has been revised to reflect branch policies and addenda.

EXECUTIVE SUMMARY:

Product Chemistry

	∙	All pertinent data requirements concerning the captan TGAI are
satisfied for Makteshim Agan and Tomen (Captan Task Force) technical
products; however, manufacturing-use product (MP) data remain
outstanding for these technical products and for the Tomen Formulation
Intermediates (FIs) as noted in the data summary tables beginning on
page 9 of the Product Chemistry Chapter.

	Also the new data requirement concerning UV/visible absorption for the
pure active ingredient (PAI) (OPPTS 830.7050) remains outstanding.

Residue Chemistry

∙	The existing data base for captan is substantially complete.  Plant
metabolism data provide adequate identification/characterization of the
terminal residues.  Sufficient crop field trial data are available to
reassess all tolerances for raw and processed plant commodities.   Based
on existing, acceptable data from the livestock metabolism studies in
progress, HED concludes the terminal residues in livestock are
adequately identified/characterized.  HED  has reassessed the tolerances
for livestock commodities and recommend for tolerance increases and new
animal commodity tolerances. 

Dietary Exposure/Risk Assessment

∙	Anticipated residues will be provided to DEEM for all commodities
and should be used when calculating the dietary risk assessment 
associated with the RED.  Although the database for captan is
substantially complete, additional data are needed to eliminate the
uncertainties associated with the exposure/risk assessment as outlined
below. The anticipated residue values are the best estimates HED can
provide using the residue data available at the time of the RED.  These
values have an inherent uncertainty associated with variations in
analytical methods, geographical representation of field trials,
seasonal variation of residue levels, etc.

cc : Chem F, Chron F. Morton 

RDI:Team: 4/30/99; SVH:4/30/99

TM, Thurston Morton, Rm. 816D CM2, 305-6691, mail code 7509C

CAPTAN

REREGISTRATION ELIGIBILITY DOCUMENT:

PRODUCT CHEMISTRY CONSIDERATIONS

(Shaughnessy No. 081301; Case No. 0120)

(DP Barcode D255103)

DESCRIPTION OF CHEMICAL

Captan (N-trichloromethylthio-4-cyclohexene-1,2-dicarboximide) is a
broad-spectrum fungicide classified as a dicarboximide or chlorinated
organosulfur compound, which is widely used as a seed treatment and has
foliar uses on several fruits and almonds.

				Empirical Formula:		C9H8Cl3NO2S

				Molecular Weight:		300.61

				CAS Registry No.:		133-06-2

				Shaughnessy No.:		081301

IDENTIFICATION OF ACTIVE INGREDIENT

Technical captan is a white to buff powder with a melting point of
158-164 C and a vapor pressure of less than 10-6 mm Hg at 25 C.  Captan
is practically insoluble in water, and is soluble in acetone, ethanol,
kerosene, xylene, chloroform, and benzene.

MANUFACTURING-USE PRODUCTS

A search of the Reference Files System (REFS) conducted 11/30/93
identified seven captan manufacturing-use products (MPs) registered
under Shaughnessy No. 081301 which are listed in Table 1.  Only these
MPs are subject to a reregistration eligibility decision.

Table 1.	Captan Manufacturing-Use Products

Formulation	EPA Reg. No.	Registrant	Transferred from

EPA Reg. No.	Date

90% FI a	19713-258	Drexel Chemical Company	--	--

90% T	7501-24	Gustafson, Inc.	--	--

92% T b	11678-1	Makhteshim Chemical Works Ltd.	--	--

92% T	New  66330-32

Old  10182-262

32691-1	12/22/87

90% T	New  66330-31

Old  10182-197

476-2099	12/22/87

90% T	New  66330-33

Old  10182-293	Tomen Agro, Inc. c	239-1246	5/25/89

88.92% FI	New  66330-34

Old  10182-198

476-2100	12/22/87

87% FI	10182-298	Canceled 7/19/95	239-2351	5/25/89

a Identified as a technical product in the Captan Update dated 12/31/91.

b Identified as a 90% formulation in the Captan Update dated 12/31/91.

c Formerly Zeneca, Inc.

REGULATORY BACKGROUND

The regulatory background for captan products in terms of comprehensive
product chemistry reviews is presented below.

	September 1985 Rereg. Standard

December 1991 Update

	Products	

Data required	Data submitted in response	

Data required	Data submitted in response

90% FI

(19713-258)	not registered at this time	n/a a	61-1, -2, -3

62-1, -2, -3

63-2 through -20	none

90% T

(7501-24)	61-2, -3

62-1, -2, -3

63-2, -3, -4, -5,

 -7, -8, -11, -12,

 -13	none	61-1, -2, -3

62-1, -2, -3

63-2 through -20	none

92% T

(11678-1)	61-2, -3

62-1, -2, -3	61-1, -2, -3

62-1, -2, -3

63-5, -7, -8, 

  -11, -12, -13	63-14, -16, -17, 

  -20	none

92% T

(66330-32)	61-2, -3

62-1, -2, -3

63-4, -5, -7, -11,

 -12, -13	none	61-1, -2, -3

62-1, -2, -3

63-2 through -20	61-1

62-2

90% T

(66330-31)	61-2, -3

62-1, -2, -3

63-4, -5, -7, -11,

 -12, -13	61-2, -3

62-1, -3

63-4, -5, -7, -8

  -11, -12, -13	61-1

62-2

63-14, -16, -17,

  -20	61-1

62-2

90% T

(66330-33)	61-2, -3

62-1, -2, -3

63-4, -5, -7, -8,

 -11, -12, -13	61-1, -2, -3

62-1, -2, -3

63-5, -7, -8 -11, 

  -12, -13	62-2

63-14, -16,

  -17, -20	61-1

62-2

88.92% FI

(66330-34)	61-2, -3

62-1, -2, -3	61-1, -2, -3

62-1, -2, -3	61-1, -2

62-2

63-2 through -7,

  -12, -14

  through -20	none

a n/a = not applicable.

OPPTS 830 Series Guideline Conversion

1982 Guideline                                                         
830 Guideline

	61-1	830.1550

61-2	830.1600/1620/1650

61-3	830.1670

62-1	830.1700

62-2	830.1750

62-3	830.1800

63-2	830.6302

63-3	830.6303

63-4	830.6304

63-5	830.7200

63-6	830.7220

63-7	830.7300

63-8	830.7840/7860

63-9	830.7950

63-10	830.7370

63-11	830.7550/7560/7570

63-12	830.7000

63-13	830.6313

63-14	830.6314

63.15	830.6315

63-16	830.6316

63-17	830.6317

63-18	830.7100

63-19	830.6319

63-20	830.6320

63-21	830.6321

none	830.7050

HED has concluded (CBRS No. 10655, D183104, dated 2/22/93, by R.
Perfetti) that the three Tomen technical products are identical, and
that data for any one of the three products can be shared by the other
two products.  Although Tomen claims that the captan formulation
intermediates are similar enough to share data, CSFs on file with the
Agency indicate a slight difference in composition.  HED has concluded
(CBRS No. 9780, D177146, dated 6/26/92, by C. Olinger) that a
justification is required for each data requirement for which the
registrant intends to share FI data.

The current status of the product chemistry data requirements for captan
products is presented in the attached data summary tables.  Refer to
these tables for a listing of the outstanding product chemistry data
requirements.  

CONCLUSIONS

All pertinent data requirements concerning the captan TGAI are satisfied
for the Makhteshim and Tomen technical products; however MP data remain
outstanding for these technical products and for the Tomen FIs.  All
product chemistry data are required for the Drexel and Gustafson captan
products.  Provided that the registrants submit the data required in the
attached data summary tables for the captan products and either certify
that the suppliers of beginning materials and the manufacturing
processes for the captan technical products and MPs have not changed
since the last comprehensive product chemistry review or submit complete
updated product chemistry data packages, HED has no objections to the
reregistration of captan with respect to product chemistry data
requirements.

AGENCY MEMORANDA CITED IN THIS DOCUMENT

CBRS No(s).:	2018, 2019, and 2020

DP Barcode(s):	none

Subject:		EPA Nos. 239-1246 (Chevron), 476-2099 (Stauffer), 11678-1
(Makhteshim/Agan):  Captan Technical:  Product Chemistry Data in
Response to Registration Standard.

From:		J. Garbus

To:		R. Mountfort and E. Wilson

Dated:		4/2/87

MRID(s):	40021201, 40021202, and 40021301

CBRS No(s).:	2120

DP Barcode(s):	none

Subject:		EPA No. (11678-1):  Captan Technical:  Additional Product
Chemistry Data for Makhteshim Material in Response to Registration
Standard.

From:		J. Garbus

To:		R. Mountfort and E. Wilson

Dated:		4/27/87

MRID(s):	40121701

CBRS No(s).:	2427

DP Barcode(s):	none

Subject:		EPA Reg No. 239-1246.  Additional Product Chemistry Data for
Chevron Captan Technical in Response to Registration Standard.

From:		R. Loranger

To:		R. Mountfort and E. Wilson

Dated:		8/28/87

MRID(s):	40231801

CBRS No(s).:	2472

DP Barcode(s):	none

Subject:		EPA Reg No. 11678-1.  Additional Product Chemistry Data for
Makhteshim Captan Technical in Response to Registration Standard.

From:		R. Loranger

To:		R. Mountfort and E. Wilson

Dated:		8/28/87

MRID(s):	40231201 and 40231301

CBRS No(s).:	9780

DP Barcode(s):	D177146

Subject:		Reregistration of Captan:  Captan Task Force Response to the
Reregistration Standard Update.

From:		C. Olinger

To:		C. Peterson

Dated:		6/26/92

MRID(s):	none

CBRS No(s).:	10655

DP Barcode(s):	183104

Subject:		Response to the Captan Reregistration Standard:  Product
Chemistry.

From:		R. Perfetti

To:		L. Rossi and E. Saito

Dated:		2/22/93

MRID(s):	none

PRODUCT CHEMISTRY CITATIONS

Bibliographic citations include only MRIDs containing data which fulfill
data requirements.  One additional MRID which did not satisfy the
stability requirement (830.6313), is included in bold type at the end of
this section.

References (cited):

40021201 Chevron Chemical Co. (1986) Analysis and Certification of
Product Ingredients:  Project I.D. 8615386.  Unpublished compilation. 
73 p.

40021202 Chevron Chemical Co. (1986) Physical and Chemical
Characteristics:  Project I.D. 8615387.  Unpublished compilation.  57 p.

40021301 Chevron Chemical Co. (1986) Product Identity and Composition: 
Laboratory Project ID. 8615385.  Unpublished compilation.  127 p.

40121701 Makhteshim Chemical Works Ltd. (1987) Product Chemistry: 
Translation from French to English Merpan Captan Technical:  MCW 10002. 
Unpublished study.  15 p. 

40141501 Wegner, M. (1987)  Beginning Materials, Manufacturing Process,
Formation of Impurities and Certification of Ingredient Limits:  Captan
90 Dust Base:  Project No. RRC 87-34.  Unpublished compilation prepared
by Stauffer Chemical Co.  14 p.

40141502 Bussey, R. (1987)  Preliminary Analysis of Product Samples
Captan 90 DB:  Project No. 87-02.  Unpublished compilation prepared by
Stauffer Chemical Co. 20 p.

40141503 Riggs, R. (1987)  Analytical Methods to Verify Certified
Limits:  Captan 90 Dust Base:  Project No. PRS-RLR-870326.  Unpublished
compilation prepared by Association of Official Analytical Chemists in
cooperation with Chevron Chemical Co.  15 p.

40231201 Makhteshim Chemical Works Ltd. (1987) Additional Product
Chemistry Data:  Merpan Captan Technical:  Makhteshim-Agan Project ID: 
MCW 10001.  Unpublished study.  10 p.

40231301 Makhteshim Chemical Works Ltd. (1987) Additional Product
Chemistry Data:  Merpan Captan Technical:  Makhteshim-Agan Project ID: 
MCW 10001.  Unpublished study.  16 p.

40231801 Thornberry, N. (1987) Physical and Chemical Characteristics: 
Captan Technical:  Laboratory Project ID:  8709737.  Unpublished study
prepared by Chevron Chemical Co.  4 p.

42301401 Haefele, L. (1992) Storage Stability Study: Drexel Captan 90%
Technical.  Unpublished study prepared by Drexel Chemical Co.  6 p.

Case No. 0120

Chemical No. 081301

Case Name: Captan

Registrant: Drexel Chemical Company

Product(s): 90% FI (EPA Reg. No. 19713-258)

PRODUCT CHEMISTRY DATA SUMMARY

Guideline

Number	

Requirement	Are Data Requirements Fulfilled? a	

MRID Number

830.1550	Product Identity and Disclosure of Ingredients	N 

	830.1600

830.1620

830.1650	Starting Materials and Manufacturing Process	N 

	830.1670	Discussion of Formation of Impurities	N 

	830.1700	Preliminary Analysis	N 

	830.1750	Certification of Ingredient Limits	N

	830.1800	Analytical Methods to Verify the Certified Limits	N 

	830.6302	Color	N 

	830.6303	Physical State	N 

	830.6304	Odor	N 

	830.6313	Stability	Nb 	42301401

830.6314	Oxidation/Reduction	N 

	830.6315	Flammability	N 

	830.6316	Explodability	N 

	830.6317	Storage Stability	N 

	830.6319	Miscibility	N 

	830.6320	Corrosion Characteristics	N 

	830.7000	pH	N 

	830.7050	UV/Visible Absorption	N/A 

	830.7100	Viscosity	N 

	830.7200	Melting Point/Melting Range	N 

	830.7220	Boiling Point/Boiling Range	N 

	830.7300	Density/Relative Density/Bulk Density	N 

	830.7370	Dissociation Constant in Water	N 

	830.7550

830.7560

830.7570	Partition Coefficient (Octanol/Water)	N 

	830.7840

830.7860	Solubility	N 

	830.7950	Vapor Pressure	N 

	

a Y = Yes; N = No; N/A = Not Applicable. 

b These data do not satisfy the data requirements of 40 CFR §158.190
(Guideline Reference  No. 830.6313) concerning storage stability because
data are required on stability to heat, metal/metal ions, and light.
Data were presented only on stability at ambient conditions in an
unspecified container. There was no appreciable decrease in captan
concentration over 18 months.

Case No. 0120

Chemical No. 081301

Case Name: Captan

Registrant: Gustafson, Inc.

Product(s): 90% T (EPA Reg. No. 7501-24)

PRODUCT CHEMISTRY DATA SUMMARY

Guideline

Number	

Requirement	Are Data Requirements Fulfilled? a	

MRID Number

830.1550	Product Identity and Disclosure of Ingredients	N

	830.1600

830.1620

830.1650	Starting Materials and Manufacturing Process	N 

	830.1670	Discussion of Formation of Impurities	N 

	830.1700	Preliminary Analysis	N 

	830.1750	Certification of Ingredient Limits	N 

	830.1800	Analytical Methods to Verify the Certified Limits	N 

	830.6302	Color	N 

	830.6303	Physical State	N 

	830.6304	Odor	N 

	830.6313	Stability	N 

	830.6314	Oxidation/Reduction	N

	830.6315	Flammability	N

	830.6316	Explodability	N 

	830.6317	Storage Stability	N 

	830.6319	Miscibility	N

	830.6320	Corrosion Characteristics	N 

	830.7000	pH	N 

	830.7050	UV/Visible Absorption	N

	830.7100	Viscosity	N 

	830.7200	Melting Point/Melting Range	N 

	830.7220	Boiling Point/Boiling Range	N 

	830.7300	Density/Relative Density/Bulk Density	N 

	830.7370	Dissociation Constant in Water	N

	830.7550

830.7560

830.7570	Partition Coefficient (Octanol/Water)	N 

	830.7840

830.7860	Solubility	N 

	830.7950	Vapor Pressure	N

	

a Y = Yes; N = No; N/A = Not Applicable.

Case No. 0120

Chemical No. 081301

Case Name: Captan

Registrant:  Makhteshim Chemical Works, Ltd.

Product(s): 92% T (EPA Reg. No. 11678-1)

PRODUCT CHEMISTRY DATA SUMMARY

Guideline

Number	

Requirement	Are Data Requirements Fulfilled? a	

MRID Number b

830.1550	Product Identity and Disclosure of Ingredients	Y	CSFc

830.1600

830.1620

830.1650	Starting Materials and Manufacturing Process	Y 	40121701
40231301

830.1670	Discussion of Formation of Impurities	Y 	40121701

830.1700	Preliminary Analysis	Y 	40021201

830.1750	Certification of Ingredient Limits	Y 	CSFc

830.1800	Analytical Methods to Verify the Certified Limits	Y 	40021201

830.6302	Color	Y 	N/A

830.6303	Physical State	Y 	N/A

830.6304	Odor	Y 	N/A

830.6313	Stability	Y	40231201

830.6314	Oxidation/Reduction	N

	830.6315	Flammability	N/A

	830.6316	Explodability	N

	830.6317	Storage Stability	N 

	830.6319	Miscibility	N/A

	830.6320	Corrosion Characteristics	N 

	830.7000	pH	Y 	40231201

830.7050	UV/Visible Absorption	N/A

	830.7100	Viscosity	N/A

	830.7200	Melting Point/Melting Range	Y	40231201

830.7220	Boiling Point/Boiling Range	N/A

	830.7300	Density/Relative Density/Bulk Density	Y 	40231201

830.7370	Dissociation Constant in Water	N/A

	830.7550

830.7560

830.7570	Partition Coefficient (Octanol/Water)	Y	40021202

830.7840

830.7860	Solubility	Y	40231201

830.7950	Vapor Pressure	Y	N/A

a Y = Yes; N = No; N/A = Not Applicable.

b Bolded citations were reviewed under CBRS No. 2018, 2019, and 2020,
dated 4/2/87, by J. Garbus; underlined citations were reviewed under
CBRS No. 2120, dated 4/27/87, by J. Garbus; italicized citations were
reviewed under CBRS No. 2472, dated 8/28/87, by R. Loranger.

c Data were initially addressed under CBRS No. 2120, dated 4/27/87, by
J. Garbus, but were re-evaluated when data required for other guidelines
were submitted under CBRS No. 2472, dated 8/28/87, by R. Loranger.

Case No. 0120

Chemical No. 081301

Case Name: Captan

Registrant: Tomen

Product(s): 90% T (EPA Reg. Nos. 66330-31, 66330-32, and 66330-33)

PRODUCT CHEMISTRY DATA SUMMARY

Guideline

Number	

Requirement	Are Data Requirements Fulfilled? a	

MRID Numberb

830.1550	Product Identity and Disclosure of Ingredients	Y b	CSF 9/15/92
c

830.1600

830.1620

830.1650	Starting Materials and Manufacturing Process	Y 	40021301

830.1670	Discussion of Formation of Impurities	Y 	40021301

830.1700	Preliminary Analysis	Y 	40021201

830.1750	Certification of Ingredient Limits	Y	CSF 9/15/92 c

830.1800	Analytical Methods to Verify the Certified Limits	Y 	40021201

830.6302	Color	Y 	N/A

830.6303	Physical State	Y 	N/A

830.6304	Odor	Y 	40021202

830.6313	Stability	Y 	40021202 40231801

830.6314	Oxidation/Reduction	N 

	830.6315	Flammability	N/A 

	830.6316	Explodability	N

	830.6317	Storage Stability	N 

	830.6319	Miscibility	N/A 

	830.6320	Corrosion Characteristics	N 

	830.7000	pH	Y 	40021202 40231801

830.7050	UV/Visible Absorption	N 

	830.7100	Viscosity	N/A 

	830.7200	Melting Point/Melting Range	Y 	40021202 40231801

830.7220	Boiling Point/Boiling Range	N/A 	N/A

830.7300	Density/Relative Density/Bulk Density	Y 	40021202 40231801

830.7370	Dissociation Constant in Water	N/A 

	830.7550

830.7560

830.7570	Partition Coefficient (Octanol/Water)	Y 	40021201

830.7840

830.7860	Solubility	Y 	40021202 40231801

830.7950	Vapor Pressure	Y 	N/A

a Y = Yes; N = No; N/A = Not Applicable.  The Agency has concluded (CBRS
No. 10655, D183104, dated 2/22/93 by R. Perfetti) that the three Zeneca
(now Tomen) technical products are identical, and that data for any one
of the three products can be shared by the other two products.

b Bolded citations were reviewed under CBRS No. 2018, 2019, and 2020,
dated 4/2/87, by J. Garbus; underlined citations were reviewed under
CBRS No. 2427, dated 8/28/87, by R.. Loranger; and the remaining
citations were reviewed under CBRS No. 10655, D183104, dated 2/22/93, by
R. Perfetti.

Case No. 0120

Chemical No. 081301

Case Name: Captan

Registrant: Tomen

Product(s): 88.92% FI (EPA Reg. No. 66330-34)

PRODUCT CHEMISTRY DATA SUMMARY

Guideline

Number	

Requirement	Are Data Requirements Fulfilled? a	

MRID Numberb

830.1550	Product Identity and Disclosure of Ingredients	Nc	40141501

830.1600

830.1620

830.1650	Starting Materials and Manufacturing Process	Nd 	40141501

830.1670	Discussion of Formation of Impurities	Y 	40141501

830.1700	Preliminary Analysis	N/Ae 

	830.1750	Certification of Ingredient Limits	Nf	40141501

830.1800	Analytical Methods to Verify the Certified Limits	Y 	40141502
40141503

830.6302	Color	N 

	830.6303	Physical State	N 

	830.6304	Odor	N 

	830.6313	Stability	N/Ae 

	830.6314	Oxidation/Reduction	N 

	830.6315	Flammability	N 

	830.6316	Explodability	N

	830.6317	Storage Stability	N 

	830.6319	Miscibility	N 

	830.6320	Corrosion Characteristics	N 

	830.7000	pH	N 

	830.7050	UV/Visible Absorption	N/A 

	830.7100	Viscosity	N 

	830.7200	Melting Point/Melting Range	N/Ae 

	830.7220	Boiling Point/Boiling Range	N/Ae 

	830.7300	Density/Relative Density/Bulk Density	N 

	830.7370	Dissociation Constant in Water	N/Ae 

	830.7550

830.7560

830.7570	Partition Coefficient (Octanol/Water)	N/Ae 

	830.7840

830.7860	Solubility	N/Ae 

	830.7950	Vapor Pressure	N/Ae 

	

a Y = Yes; N = No; N/A = Not Applicable. 

bAll citations were reviewed in the Captan Reregistration Standard
Update dated 12/31/91.

cThese data do not satisfy the data requirements of 40 CFR §158.155
(Guideline Reference No. 830.1550) concerning product composition
because the nominal concentration of the active ingredients (captan and
related derivatives) must be revised to represent the level of the
active ingredients in the final product based on the concentration of
the active ingredients in the technical source product.

dThese data do not satisfy the data requirements of 40 CFR §158.160-165
(Guideline Reference No. 830.1600, 1620, 1650) concerning the starting
materials and manufacturing process because a specification sheet for an
inert ingredient must be submitted.

eThese data requirements will be satisfied by the technical source
product.

fThese data do not satisfy the data requirements of 40 CFR §158.175
(Guideline Reference No. 830.1750) concerning certified limits because
an updated CSF on EPA Form 8570-4 (Rev. 12-90) is required reflecting
transfer of ownership.

CAPTAN

REREGISTRATION ELIGIBILITY DOCUMENT

RESIDUE CHEMISTRY CONSIDERATIONS

(Shaughnessy No. 081301; Case 0120)

(DP Barcode D255103)

TABLE OF CONTENTS	page

 TOC \f 

INTRODUCTION	 18

REGULATORY BACKGROUND	 18

SUMMARY OF SCIENCE FINDINGS	 20

GLN 860.1200: Directions for Use	 20

GLN 860.1300: Plant Metabolism	 20

GLN 860.1300:  Animal Metabolism	 20

GLN 860.1340 (c/d):  Residue Analytical Methods - Plants and Animals	 21

GLN 860.1380:  Storage Stability	 21

	GLN 860.1480: Magnitude of the Residue in Meat, Milk, Poultry, and Eggs
 22

GLN 860.1500: Magnitude of the Residue in Plants	 22

GLN 860.1520: Magnitude of the Residue in Processed Food/Feed	 22

GLNs 860.1850 and 860.1900: Confined/Field Rotational Crops	 22

TOLERANCE REASSESSMENT SUMMARY	 44

Tolerances Currently Listed Under 40 CFR §180.103(a)	 44

Tolerances Listed Under 40 CFR §185.500	 45

CODEX HARMONIZATION	 51

DIETARY EXPOSURE REASSESSMENT	 53

AGENCY MEMORANDA CITED IN THIS DOCUMENT	 53

MASTER RECORD IDENTIFICATION NUMBERS	 57

 

CAPTAN

REREGISTRATION ELIGIBILITY DOCUMENT

RESIDUE CHEMISTRY CONSIDERATIONS

(Shaughnessy No. 081301; Case 0120)

(DP Barcode D255103)

INTRODUCTION tc "INTRODUCTION" 

Captan (N-trichloromethylthio-4-cyclohexene-1,2-dicarboximide) is a
fungicide registered for foliar applications to almonds, apples,
apricots, blueberries, caneberries, cherries, grapes, nectarines,
peaches, plums, and strawberries; post-harvest fruit dip on apples,
cherries, and pears; and seed treatment of numerous food and feed crops.
 These are the only use patterns to be supported by the Captan Task
Force comprised of Mahketeshim-Agan and Tomen Agro, Inc., formerly
Zeneca, Inc., (letter from Zeneca dated 2/3/94) and are detailed in
Table A (amended 2/5/97, C. Olinger, D228077).  Formulations registered
for field application are the 50 and 80% wettable powder (WP), the 75%
water-dispersible granules (WDG), and the 4 lb/gal flowable concentrate
(FlC).  Several dusts (D) and WPs and a 4 lb/gal FlC are registered for
seed treatments [Source: REFS search dated 5/04/94; active end-use
product labels.]

Tolerances for residues in/on numerous plant and animal commodities are
currently expressed in terms of captan per se (a complete list of
commodities with tolerances is provided in Table C).  

REGULATORY BACKGROUND tc "REGULATORY BACKGROUND" 

A Special Review Data Call-In Notice (DCI) was issued 4/29/85 for captan
requiring a number of studies to be used by the Agency in refining
dietary exposure assessments.

Captan was the subject of a Reregistration Standard and Guidance
Document issued 3/86.  The Guidance Document specified numerous residue
chemistry data gaps.  The Captan Reregistration Standard Update dated
12/31/91 summarizes data submitted in response to the DCI and Guidance
Document and specified remaining data gaps and needed label amendments. 
The information contained in this document outlines the Residue
Chemistry Science Assessments with respect to the reregistration of
captan.

Issues

The Position Document 1 (PD1) published in 1980 (45 FR 54938) outlined
the oncogenic, teratogenic, and reproductive effects of captan.  The
PD2/3 (1985) summarized the potential risks and benefits of captan use. 
The PD2/3 recommended the cancellation of all foliar and postharvest
food/feed uses of captan and retention of seed treatment uses.  However,
additional data were required to support established tolerances and to
determine the actual food residues.  In addition the PD2/3 stated that
uses would be retained where submitted data demonstrate that actual
residues are lower than the established tolerance or in cases where
modified use patterns would reduce dietary risk.

The Agency's Special Review and Risk/Benefit Analysis concluded that
retention of all food uses of captan would result in unreasonable
adverse effects on humans or the environment.  Consequently, the Agency
announced (PD4; FR Notice of 2/24/89, Vol. 54, No. 36, p. 8116) a notice
of intent to cancel the registrations of all products containing captan
as the active ingredient with the following exceptions:  (I) all
non-food uses;  (ii) seed treatments; and (iii) the following food uses:
 almonds, apples, apricots, cherries, grapes, pears, plums,
strawberries, nectarines, pears (postharvest), and peaches, plus several
uses not canceled, but subject to suspension.  Those use sites subject
to suspension were blackberries, blueberries, celery (plant-bed),
dewberries, eggplant (plant bed), lettuce, mangoes, green onions,
peppers and pimentos (plant bed), raspberries, spinach (plant bed),
taro, and tomatoes (plant bed).  These uses were suspended due to
insufficient residue data reflecting these use patterns.  The use on
blueberries is being supported by the Captan Task Force.  The use on
caneberries (blackberries, dewberries, and raspberries) is being
retained with supporting data provided by IR-4.  Foliar uses on lettuce,
mangoes, and green onions and plant-bed use registrations listed in the
PD4 as subject to suspension are not being supported by the Captan Task
Force.

The HED Metabolism Committee (C. Olinger and P. Chin, 4/1/94) has ruled
that the tolerance expression for animal commodities is to be revised to
include the metabolite 1,2,3,6-tetrahydrophthalimide (THPI) as well as
captan.  Captan per se is to remain the only residue regulated by
tolerances in raw and processed plant commodities.  The structures of
captan and THPI are shown below.

 

	

Captan	THPI

SUMMARY OF SCIENCE FINDINGS tc "SUMMARY OF SCIENCE FINDINGS" 

The summaries of residue chemistry guidelines and topics listed below
are based on the present regulatory status where the only registered
food/feed uses of captan are those to be retained by the Captan Task
Force.  HED reserves the right to require additional studies for each
applicable guideline and topic if additional registrations on food/feed
crops are sought.  A complete summary of residue chemistry data
requirements for the reregistration of captan, in accordance with OPPTS
Test Guidelines Series 860, appears in Table B.

GLN 860.1200: Directions for Use  tc "GLN 860.1200\: Directions for Use
" \l 2 :  There are 30 end-use products (EP) of captan currently
registered by Tomen (formerly Zeneca) for food/feed crops [Source:  REFS
search conducted 4/05/99].  Only WP, FlC, and WDG formulations are
registered for foliar applications.  Dusts, in addition to the
aforementioned formulation classes, are registered for seed treatment. 
The only foliar (or post-harvest dip) uses are on apples, pears, grapes,
strawberries, cherries, peaches, almonds, apricots, caneberries, plums,
and blueberries. A comprehensive summary of registered food/feed use
patterns based on these product labels is presented in Table A (EPA Reg.
Nos. 66330-26, -10, -1, -11, -27, -12, -28, -23, -24, -2, -3,  -4, -25,
-5, -13, -14, -15, -16, -17, -18, -19, -6, -20, -7, -8, -21, -22, -9,
-30; uses permitted under CA930007 for foliar application to pears and
SC920001 for chemigation of strawberries were also used).  CA930007 is
listed in REFS (4/27/99) as cancelled. Zeneca has requested voluntary
cancellation of 10182-153, -313 and -314 in a letter dated 10/25/93 and
products 10182-289, -295, -305, and -315 in a letter dated 2/24/94. 
These products were still considered active in a REFS search conducted
5/04/94. Product 70-190 is still listed as active in REFS (4/27/99).
Foliar use on pears must be cancelled on this product because the PD4
disallowed this use. Also 239-568 has a foliar use on pears. In REFS
this is listed as Ortho Home Orchard Spray. Use on pears was disallowed
in the PD4. A risk management decision by SRRD would have to be made
whether PD4 apply to home uses also. Uses cancelled in the PD4 must be
deleted from the labels.

The conclusions regarding the reregistration eligibility of captan on
the crops listed in Table B are based on the use patterns registered by
members of the Captan Task Force for which residue data are available
reflecting these use patterns.  Modifications are still required for
some Zeneca labels including maximum seasonal use rates, pre-harvest
intervals, and other use restrictions.  When end-use product DCIs are
developed (e.g., at issuance of the RED), RD should require that all
end-use product labels (e.g., MAI labels, SLNs, and products subject to
the generic data exemption) be amended such that they are consistent
with the basic producer labels. 

GLN 860.1300: Plant Metabolism  tc "GLN 860.1300\: Plant Metabolism " \l
2 :  The qualitative nature of the residue in plants is adequately
understood based on acceptable lettuce and tomato metabolism studies. 
These studies indicated that captan is cleaved at the N-S bond to form
THPI, which is further metabolized.  The metabolite of the cleaved side
chain is carbon dioxide (CO2), which may be reincorporated into plant
constituents.  Captan is the major residue in tomato fruits and lettuce
comprising 55-81% of the total radioactive residue (TRR).  Minor
residues include THPI, (4-9% of the TRR), captan epoxide, (0.4%), and
THPI epoxide (0.9%).  Bis(trichloromethyl)disulfide,
trans-3-hydroxy-1,2,6-trihydrophthalimide (3-OH-THPI), and
trans-5-hydroxy-1,2,6-trihydrophthalimide (5-OH-THPI) may be present at
very low levels.  The residue of concern in raw and processed plant
commodities is captan per se.

GLN 860.1300:  Animal Metabolism  tc "GLN 860.1300\:  Animal Metabolism
" \l 2 : The qualitative nature of the residue in animals is adequately
understood, based on acceptable poultry and ruminant metabolism studies
with cyclohexyl ring-labeled (CHR) [14C]captan.  No captan was detected
in tissues, milk, or eggs.  The major residues in goat muscle, liver,
kidney and milk are 3-OH-THPI and 5-OH-THPI; in addition THPI was a
major residue in goat fat.  THPI was the major residue in hen matrices. 
Captan metabolism in livestock proceeds through rapid cleavage of the
trichloromethyl moiety, followed by oxidation and hydroxylation of the
cyclohexyl ring.  The trichloromethyl carbon is taken up into the single
carbon pool and incorporated into natural constituents. Sufficient data
are available to assess the dietary risk from animal commodities bearing
captan residues. The residues of concern in animals are captan and THPI.

GLN 860.1340:  Residue Analytical Methods - Plants and Animals  tc "GLN
860.1340\:  Residue Analytical Methods - Plants and Animals " \l 2 : 
Adequate methodology is available for enforcement of tolerances residues
of captan per se in/on plant commodities.  A GC/electron capture
detection (EC) method included in PAM, Vol. II as Method I is the
preferred enforcement method.  Other methods in PAM Vol. II that use
colorimetry to analyze surface residues from plant tissues are not
acceptable.  Data submitted to support crop tolerances and in response
to the DCI (residue reduction) were collected using the following GC
methods:  Chevron Methods No. RM-1K-1 and RM-1K-2 for captan and THPI,
Stauffer Method No. RRC-76-30R for captan and RRC-78-20 for THPI, and
Zeneca (formerly ICI) Method No. WRC 89-51 for captan and THPI.

Zeneca Method No. 166 for quantifying THPI in meat and milk has been
validated for use in tolerance enforcement.  This method has also been
used for data collection and is adequate for that purpose.

Captan is completely recovered (>80%) using PAM Vol. I Multiresidue
Protocol E, Section 211.1 for oily matrices and partially recovered
(50-85%) using Protocol E Section 212.1 for non-oily matrices.  Captan
is completely recovered using Multiresidue Protocol D (Luke Method;
232.4).  THPI is completely recovered through Protocol D, but not
through Protocol E (PESTDATA, PAM, Vol. 1, Appendix, 8/93).

GLN 860.1380:  Storage Stability  tc "GLN 860.1380\:  Storage Stability
" \l 2 :  Storage stability studies have been conducted with crop
matrices.  The stability of captan is somewhat dependent on the extent
of sample preparation.  Captan per se is stable for periods of 3-14
months in whole almonds, apples, apple juice, apple sauce, grape dry
pomace, raisins, spinach, strawberries, sugar beet tops, tomato dry
pomace, and tomato sauce, and for 3 months in cherries and wheat forage.
 Captan per se was not stable in almonds, corn grain, or spinach that
had been ground prior to fortification or in beet tops, whole corn
grain, cucumbers, lettuce, potatoes, soybean seed and forage, or
tomatoes.  As captan degrades to THPI, which exhibits greater stability,
the total captan plus THPI residues can show the overall stability of
total residues.  Captan plus THPI residues were stable for 9-15 months
on whole almonds, apples, apple juice, applesauce, beet tops, cherries,
cucumbers, grape dry pomace, raisins, soybean forage, chopped spinach,
strawberries, sugar beet tops, tomato dry pomace, tomato sauce, and
wheat forage.  Combined residues were stable for 3-6 months in lettuce,
potatoes, and soybean grain, and for 1-2 months in ground almonds,
ground corn grain, and finely chopped spinach.  The data are adequate to
support the residue data submitted to support foliar applications and
seed treatments.  Additional storage stability data may be required to
support any new magnitude of residue data submitted in the future.

Sufficient storage stability data are available to support the residue
data for milk.  THPI residues are stable in animal tissues for 3 years
when results are corrected for concurrent method recoveries (D214345,
D222419; C. Olinger, 5/30/96). No additional storage stability data are
required for animal commodities.

GLN 860.1480: Magnitude of the Residue in Meat, Milk, Poultry, and Eggs:
 Cattle feeding studies have been evaluated and found adequate to
satisfy ruminant feeding study data requirements.  Using Table 1 GLN
860.1000, the maximum theoretical dietary burden for dairy cattle is
17.27 ppm and beef cattle is 27.72 ppm, based on residue contributions
from wet apple pomace (40% dry matter), almond hulls, and RAC’s from
seed treatment.  The feeding study data represent daily dietary levels
of 10, 30, and 100 ppm and are adequate for assessing the established
tolerances and establishing a new tolerance for milk.

Table 2.  Estimated Dietary Burden

Commodity	Captan + THPI

(ppm)	% in Diet

% Dry Matter	Average Dietary Burden, ppm

	Dairy	Beef

Dairy	Beef

Almond Hulls	60 1	10	10	90	6.67	6.67

Apple Pomace, wet	20.82	20	40	40	10.40	20.80

RAC's from seed treatment (grass, corn, cottonseed, small grain etc.)
0.1 3	40	50	20 4	0.20	0.25

TOTAL

70	100

17.27	27.72

1 The maximum residue found at a 1x rate in FT for almond hulls was 60
ppm captan + THPI.

2 The maximum residue found at a 1x rate in FT for apples was 15.9 ppm
captan + THPI.

   Apple pomace: 20.8(16x1.3 avg. conc. factor for captan + THPI)

3  Limit of detection for THPI plus limit of detection for captan, 0.05
ppm + 0.05 ppm.

4  Maximizes residue.  20% is the percent dry matter for potato culls.
Other rac's typically have higher percent dry matter.

A poultry feeding study is not required.  Using Table 1 GLN 860.1000,
the only poultry feed items which remain are those grown from captan
treated seed.  Since residues of captan and THPI are not detectable in
the poultry feed items, poultry feeding studies and tolerances will not
be required.

GLN 860.1500: Magnitude of the Residue in Plants:  All data requirements
for magnitude of the residue in plants have been evaluated.   Data are
adequate to reassess captan tolerances in light of canceled and revised
uses.  Field data on fruit and nut orchard crops and grapes are
available reflecting multiple foliar applications of WP, FlC, or WDG
formulations with appropriate PHIs and geographic representation.  Data
on postharvest fruit dip are available for apples, cherries, and pears. 
Data from seed treatments using WP/FlC and D formulations on
representative crop seed and potato seed pieces indicate that these uses
will not result in detectable residues of captan in/on edible
commodities.

In addition, the Task Force is not supporting the EC/SC (5887-167)
foliar use on apples, cherries, grapes, peaches, and (4-122) on
strawberries. Data will be required to support these uses or they must
be deleted from the product label. These data are considered
confirmatory.

GLN 860.1520: Magnitude of the Residue in Processed Food/Feed  tc "GLN
860.1520\: Magnitude of the Residue in Processed Food/Feed " \l 2 :  All
data requirements for magnitude of the residue in processed food/feed
have been evaluated and deemed adequate to determine the extent to which
residues concentrate in food/feed items upon processing of the raw
agricultural commodity.  Captan residues tend to concentrate in raisins
and raisin waste.  Raisin waste is no longer a significant feed item per
Table 1 OPPTS GLN 860.1000, therefore, no feed tolerance is required.
Residues tend to reduce or convert to THPI in all other processed
commodities. 

GLN 860.1560: Reduction of Residue:  Data pertaining to reduction of
captan residues on plant commodities were submitted in response to the
Special Review of captan.  Studies conducted on apples, cantaloupe,
cucumbers, grapefruit, lemons, lettuce, oranges, squash, strawberries,
and spinach indicate that residues are substantially reduced by washing
and are almost non-detectable after peeling.  Cooking studies on celery,
cucumbers, squash, and spinach indicate that residues of captan are
almost non-detectable after cooking, with a corresponding increase in
the THPI residues.

GLNs 860.1850 and 860.1900: Confined/Field Rotational Crops  tc "GLNs
860.1850 and 860.1900\: Confined/Field Rotational Crops " \l 2 : 
Confined rotational crop studies were reviewed previously by EFGWB and
judged unacceptable due to low field application rates.  However, since
the EFGWB review, captan use patterns have become more restrictive, such
that the only uses pertinent to rotational crops are seed treatments. 
There are no captan uses on annual crops.  The studies have been
reconsidered under the current use patterns, and it has been concluded
that no detectable residues of captan or THPI are likely in rotated
crops and that no field rotational crop data or tolerances for rotated
crops are required.

Table A.	Use patterns subject to reregistration for:  Case 0120,
Captan.

SITE

Application Type

Application Timing

Application Equipment	Maximum Application Rate

(ai)	Form	Maximum  Seasonal Rate

 (ai)	Minimum Retreatment Interval (days)	PHI

(days)	Use Limitations

Alfalfa, Clover

Seed treatment

Slurry	4 oz/cwt	WP, FlC	NAa	NA	NA

	Seed treatment

Dust	6 oz/cwt	D

Seed treatment

Planter box	0.25 oz/cwt	D

Almonds

Foliar

Ground and aerial equipment	5 lb/A	WP, FlC, WDG	26.25 lb/A	NSb	30

	Apples

Foliar

Ground and aerial equipment	4 lb/A	FlC, WDG, WP	32 lb/A	5	0	Eastern U.S.

	32 lb/A	NS	0	Western U.S.

Postharvest fruit dip	1.25 lb/

100 gal	WP, FlC, WDG	NA	NA	NA

	Apricots

Foliar

Ground and aerial equipment	2.5 lb/A	WP, FlC, WDG	12.5 lb/A	NS	0

	Barley

Seed treatment

Dust or slurry	1.5 oz/cwt	D, WP,  FlC	NA	NA	NA

	Seed treatment

Planter box

	0.8 oz/cwt c	D

Beans

Seed treatment

Slurry	1.3 oz/cwt	WP, FlC	NA	NA	NA

	Seed treatment

Dust	1.9 oz/cwt	D

Seed treatment

Planter box	0.25 oz/cwt	D

Beets (table)

Seed treatment

Slurry	6 oz/cwt	WP, FlC	NA	NA	NA

	Seed treatment

Dust	9 oz/cwt	D

Blueberries

Foliar

Ground and aerial equipment	2.5 lb/A	WP, FlC, WDG	35 lb/A	7	0	

Bluegrass

Seed treatment

Slurry	4.1 oz/cwt	WP, FlC	NA	NA	NA

	Seed treatment

Dust	6 oz/cwt	D

Broccoli, Brussels sprouts, cabbage, cauliflower

Seed treatment

Dust or slurry	1.1 oz/cwt	D, WP, FlC 	NA	NA

	NA

	Seed treatment

Planter box	0.25 oz/cwt	D

Carrots

Seed treatment

Slurry	4.4 oz/cwt	WP, FlC 	NA	NA	NA

	Seed treatment

Dust	6.75 oz/cwt	D

Seed treatment

Planter box	0.5 oz/cwt	D

Cantaloupe, cucumber

Seed treatment

Slurry	1.6 oz/cwt	WP, FlC 	NA	NA	NA

	Seed treatment

Dust	2.25 oz/cwt	D

Seed treatment

Planter box	0.5 oz/cwt	D

Cherries

Foliar

Ground and aerial equipment	2 lb/A	WP, FlC, WDG	14 lb/A	3	0	Eastern U.S.

NS	0	Western U.S.

Postharvest fruit dip	1.25 lb/

100 gal	WP, FlC, WDG	NA	NA	NA

	Corn (field)

Seed treatment

Dust or slurry	1.1 oz/cwt	D, WP, FlC 	NA	NA	NA

	Corn (sweet)

Seed treatment

Dust or slurry	2 oz/cwt	D, WP, FlC 	NA	NA	NA

	Corn (unspecified)

Seed treatment

Planter box	1 oz/cwt	D	NA	NA	NA

	Cotton, acid delinted

Seed treatment

Slurry	2.5 oz/cwt	FlC, WP	NA	NA	NA

	Seed treatment

Dust	1.5 oz/cwt	D

Cotton, machine delinted

Seed treatment

Dust or slurry	2.25 oz/cwt	D, WP, FlC 	NA	NA	NA

	Cotton, fuzzy

Seed treatment

Slurry or dust	2.25 oz/cwt	D, WP	NA

	NA	NA

	Seed treatment

Slurry	3.5 oz/cwt	FlC, WP

Cotton, reginned

Seed treatment

Slurry	3.5 oz/cwt	FlC	NA	NA	NA

	Cotton (unspecified)

Seed treatment

Planter box	1 oz/cwt	D	NA	NA	NA

	Cowpeas

Seed treatment

Slurry	1.5 oz/cwt	WP, FlC 

NA	NA

	Seed treatment

Dust	2.25 oz/cwt	D

Eggplant

Seed treatment

Slurry	2.7 oz/cwt	WP 	NA	NA	NA

	Seed treatment

Dust	4.5 oz/cwt	D

Flax

Seed treatment

Slurry	2 oz/cwt	WP, FlC 	NA	NA	NA

	Seed treatment

Dust	2.6 oz/cwt	D

Seed treatment

Planter box	0.25 oz/cwt	D

Grapes

Foliar

Ground and aerial equipment	2 lb/A	WP, FlC, WDG	12 lb/A	10	0	U.S. exc.
CA

NS	0	CA

Grasses

Seed treatment

Slurry	4.1 oz/cwt	WP, FlC	NA	NA	NA

	Seed treatment

Dust	9 oz/cwt	D

Mustard, rape

Seed treatment

Slurry	0.8 oz/cwt	WP, FlC	NA	NA	NA

	Nectarines

Foliar

Ground and aerial equipment	4 lb/A	WP, FlC, WDG	24 lb/A	3	0	U.S. 

Oats

Seed treatment

Dust or slurry	2 oz/cwt	WP,  FlC 	NA	NA	NA

	Seed treatment

Planter box	0.8 oz/cwt	D

Okra

Seed treatment

Planter box

	0.5 oz/cwt	D	NA	NA	NA

	Onion

Pelleting	0.8 lb/lb seed	D, FlC	NA	NA	NA

	Seeder box treatment	0.75 lb/3 lb seed	D, WP, FlC 

Peaches

Pre-Plant Root Dip	2 lb/100 gal water	WP, WDG	NA	NA	NA	CA

Foliar

Ground and aerial equipment	4 lb/A	WP, FlC, WDG	32 lb/A	3	0	U.S. 

Peanuts

Seed treatment

Dust or slurry	3 oz/cwt	D, FlC, WP	NA	NA	NA

	Pears

Canceled use per PD4. Foliar

Ground and aerial equipment	3 lb/A	WP	NS	NS	14	CA only under EPA SLN No.
CA 930007

Postharvest fruit dip	1.25 lb/

100 gal	WP, FlC, WDG	NA	NA	NA

	Peas

Seed treatment

Slurry	1.3 oz/cwt	WP, FlC 	NA	NA	NA

	Seed treatment

Dust	1.9 oz/cwt	D

Seed treatment

Planter box	0.5 oz/cwt	D

Peppers

Seed treatment

Slurry	1.5 oz/cwt	WP, FlC	NA	NA	NA

	Seed treatment

Dust	2.25 oz/cwt	D

Plums/Fresh prunes

Foliar

Ground and aerial equipment	3 lb/A	WP, FlC, WDG	27 lb/A	7	0	Eastern U.S.

	27 lb/A	NS	0	Western U.S.

Potatoes

Seed piece treatment

Dust	1.2 oz/cwt	D	NA	NA	NA	

Radish

Seed treatment

Dust or slurry	1.1 oz/cwt	D, WP, FlC 	NA	NA

	NA

	Seed treatment

Planter box	0.25 oz/cwt	D

Rutabaga

Seed treatment

Slurry	2.3 oz/cwt	WP,  FlC 	NA	NA	NA

	Seed treatment

Dust	3.4 oz/cwt	D

Rye

Seed treatment

Dust or slurry	1.5 oz/cwt	D, WP,  FlC	NA	NA	NA

	Seed treatment

Planter box	0.25 oz/cwt	D

Safflower

Seed treatment

Planter box	0.25 oz/cwt	D	NA	NA	NA

	Sesame

Seed treatment

Slurry

	0.8 oz/cwt	WP, FlC 	NA	NA	NA

	Sorghum - milo

Seed treatment

Slurry	3 oz/cwt	WP, FlC 	NA	NA	NA	

Sorghum - hulled

Seed treatment

Dust or slurry	3 oz/cwt	D, WP, FlC	NA	NA	NA

	Soybeans

Seed treatment

Slurry	1.3 oz/cwt	WP, FlC 	NA	NA	NA

	Seed treatment

Dust	1.9 oz/cwt	D

Seed treatment

Planter box	1.75 oz/cwt	D

Spinach

Seed treatment

Slurry	3.3 oz/cwt	WP, FlC 	NA	NA	NA

	Seed treatment

Dust	4.5 oz/cwt	D

Seed treatment

Planter box	0.5 oz/cwt	D

Squash, pumpkins, watermelon

Seed treatment

Slurry	1 oz/cwt	WP, FlC 	NA	NA	NA

	Seed treatment

Dust	1.5 oz/cwt	D 

Seed treatment

Planter box	0.5 oz/cwt	D

Strawberries

Foliar

Ground and aerial equipment	3 lb/A	WP, FlC, WDG	24 lb/A	7	0	U.S.

Chemigation permitted in SC under EPA SLN NO. SC920001

Sugar beets, Eastern U.S.

Seed treatment

Slurry	6 oz/cwt	WP, FlC	NA	NA	NA	Eastern U.S.

Sugar beets, Western U.S.

Seed treatment

Slurry	3 oz/cwt	WP, FlC	NA	NA	NA	Western U.S.

Sugar beets, unspecified

Seed treatment

Slurry	6 oz/cwt	WP, FlC 	NA	NA	NA

	Seed treatment

Dust	9 oz/cwt	D

Seed treatment

Planter box	2 oz/cwt	D

Sunflower

Seed treatment

Slurry	2 oz/cwt	FlC	NA	NA	NA

	Seed treatment

Planter box	0.5 oz/cwt	D

Swiss chard

Seed treatment

Slurry	6 oz/cwt	WP, FlC 	NA	NA	NA

	Seed treatment

Dust	9 oz/cwt	D

Turnips

Seed treatment

Slurry	1.5 oz/cwt	WP,  FlC 	NA	NA	NA

	Seed treatment

Dust	2.25 oz/cwt	D, WP,  FlC 

Wheat

Seed treatment

Slurry	1 oz/cwt	WP 

NA	NA

	Seed treatment

Dust or slurry	2 oz/cwt	FlC

Seed treatment

Planter box	0.8 oz/cwt	D

a	NA = Not applicable.

b	NS = Minimum interval between treatments not specified.

c  0.8 rate on EPA Reg. No. 10182-321

Table B.   Residue Chemistry Science Assessments for Reregistration of
Captan.

GLN:  Data Requirements	Tolerances,

ppm [40 CFR]	Must Additional Data Be Submitted?	

References1

	860.1200:  Directions for Use	N/A = Not Applicable

	Yes2

	860.1300:  Plant Metabolism	N/A	No	00058941 00083100 00096978 00098790
00098831 00128355 GS120-001 406580053 406580063 417460014 421096015

860.1300:  Animal Metabolism	N/A	No	00058940 00096901 00096908 00098786
00128355 GS120-003 GS120-004 406580023 406580033 406580043

425688017 427564018

432667016 432667026

860.1340:  Residue Analytical Methods	N/A	No9	00002927 00002928 
00003025 00025123 00025125 00025129 00035246 00035248 00042645 00042646
00045174 00045175 00045176 00045179 00045182 00045183 00045184 00045188
00045189 00053324 00054015 00054016 00070201 00071790 00083393 00085525
00085526 00090988 00090989 00096910 00096982 00097622 00098720 00098726
00098731 00098747 00098751 00098784 00098789 00098804 00098810 00098811
00098817 00098818 00098894 00117087 00128355 GS120-008 GS120-011
413930013 413865013 414069013

860.1380:  Storage Stability	N/A	No	4075230111 4103910112 4155760113
4280390114

860.1500:  Magnitude of the Residue in Plants

	Root and Tuber Vegetables Group

	 - Beet roots	2 [§180.103 (a)]	No	4018980615 4114910416

4130610117 4130610217 4146840118

 - Carrots	2 [§180.103 (a)]	No	4018980615 4114910416 4130610117
4130610217 4146840118

 - Potatoes	25 [§180.103 (b)]	No	00098716 00098894 00054016 4018980615
4114910416 4130610117 4130610217 4146840118

 - Rutabagas	2 [§180.103 (a)]	No	4018980615 4114910416 4130610117
4130610217 4146840118

 - Taro	2 [§180.103 (a)]	No19	4018980615 4114910416 4146840117
4130610117 4130610218

 - Turnip roots	2 [§180.103 (a)]	No	4018980615 4114910416 4130610117
4130610217 4146840118

Leaves of Root and Tuber Vegetables Group

	 - Beet greens	100 [§180.103 (a)]	No	4018982115 4114910216  
4130610117 4130610217 4146840118

 - Turnip greens	2 [§180.103 (a)]	No	4018982115 4114910216 4130610117
4130610217 4146840118

Bulb Vegetables Group

	 - Garlic	2 [§180.103 (a)]	No	4018980615 4114910416 4130610117
4130610217 4146840118

 - Leeks	2 [§180.103 (a)]	No	4018980615 4114910416 4130610117
4130610217 4146840118

 - Onions, dry bulb	25 [§180.103 (a)]	No	4018980615 4114910416
4130610117 4130610217 4146840118

 - Onions, green	50 [§180.103 (a)]	No	4018980615 4114910416 4130610117
4130610217 4146840118

 - Shallots	50 [§180.103 (a)]	No	4018980615 4114910416 4130610117
4130610217 4146840118

Leafy Vegetables Group

	 - Celery	50 [§180.103 (a)]	No	00070201 0015959920 4018982115
4114910216 4130610117 4130610217 4146840118

 - Lettuce	100 [§180.103 (a)]	No	00070201 0015960520 4018982115
4114910216 4130610117 4130610217 4146840118

 - Spinach	100 [§180.103 (a)]	No	00070201 0015960620 4018982115
4114910216 4114910316 4130610117 4130610217 4146840118

Brassica Leafy Vegetables Group

	 - Broccoli	2 [§180.103 (a)]	No	4018982115 4114910216 4130610117
4130610217 4146840118

 - Brussels sprouts	2 [§180.103 (a)]	No	4018982115 4114910216
4130610117 4130610217 4146840118

 - Cabbage	2 [§180.103 (a)]	No	4018982115 4114910216 4130610117
4130610217 4146840118

 - Cauliflower	2 [§180.103 (a)]	No	4018982115 4114910216 4130610117
4130610217 4146840118

 - Collards	2 [§180.103 (a)]	No	4018982115 4114910216 4130610117
4130610217 4146840118

 - Kale	2 [§180.103 (a)]	No	4018982115 4114910216 4130610117 4130610217
4146840118

 - Mustard greens	2 [§180.103 (a)]	No	4018982115 4114910216 4130610117
4130610217 4146840118

Legume Vegetables Group

	 - Beans, dry	25 [§180.103 (b)]	No	00046914 00070201 00098710
4018982015 4114910116 4130610117 4130610217 4146840118

 - Beans, succulent	25 [§180.103 (b)]	No	00046914 00070201 00098710
4018982015 4114910116 4130610117 4130610217 4146840118

 - Peas, dry	2 [§180.103 (a)]	No	4018982015 4114910116 4130610117
4130610217 4146840118

 - Peas, succulent	2 [§180.103 (a)]	No	4018982015 4114910116 4130610117
4130610217 4146840118

 - Soybeans, dry	2 [§180.103 (a)]	No	00003025 00071790 00096982
4018982015 4114910116 4130610117 4130610217 4146840118

 - Soybeans, succulent	2 [§180.103 (a)]	No	00071790 00096982 00098709
4018982015 4114910116 4130610117 4130610217 4146840118

Fruiting Vegetables Group

	 - Eggplants	25 [§180.103 (a)]	No	00098709 4018982015 4114910116
4130610117 4130610217 4146840118

 - Peppers	25 [§180.103 (a)]	No	4018982015 4114910116 4130610117
4130610217 4146840118

 - Pimentos	25 [§180.103 (a)]	No	4018982015 4114910116 4130610117
4130610217 4146840118

 - Tomatoes	25 [§180.103 (a)]	No	00070201 00085526 00098708 4018982015
4018982315 4018982415 4114910116 4130610117 4130610217 4146840118

Cucurbit Vegetables Group

	 - Cantaloupes	25 [§180.103 (a)]	No	00098818 4108982015 4114910116
4130610117 4130610217 4146840118

 - Cucumbers	25 [§180.103 (a)]	No	00098709 4108982015 4114910116
4130610117 4130610217 4146840118

 - Honeydew melons	25 [§180.103 (a)]	No	00098818 4108982015 4114910116
4130610117 4130610217 4146840118

 - Muskmelons	25 [§180.103 (a)]	No	00098818 4108982015 4114910116
4130610117 4130610217 4146840118

 - Pumpkins	25 [§180.103 (a)]	No	4108982015 4114910116 4130610117
4130610217 4146840118

 - Squash, summer	25 [§180.103 (a)]	No	00098818 4108982015 4114910116
4130610117 4130610217 4146840118

 - Squash, winter	25 [§180.103 (a)]	No	00098818 4108982015 4114910116
4130610117 4130610217 4146840118

 - Watermelons	25 [§180.103 (a)]	No	00128355 4108982015 4114910116
4130610117 4130610217 4146840118

Pome Fruits Group

	 - Apples	25 [§180.103 (a)]	No	00085526 00098711 00098722 00098789
00106602 00128355 0015959720 4018980315 4074540321 4225220110 4225220210

 - Pears	25 [§180.103 (a)]	No	00070201 00085526 00098722 00106602
00128355 4018981515

Stone Fruits Group

	 - Apricots	50 [§180.103 (a)]	No	00128355 4018980515

 - Cherries	100 [§180.103 (a)]	No	00128355 4018980815

 - Nectarines	50 [§180.103 (a)]	No	00128355 4018981315

 - Peaches	50 [§180.103 (a)]	No	00128355 4018981415 4074540621
4074540721

 - Plums (fresh prunes)	100 [§180.103 (a)]	No	00128355 4018981615

Small Fruits and Berries Group

	 - Blackberries	25 [§180.103 (a)]	 No22	4271280123

 - Blueberries (huckleberries)	25 [§180.103 (a)]	No	00046914 00070201
00090988 00128355 4103910112

 - Caneberry	25 [§180.103 (a)]	No	44227201 29

 - Dewberries	25 [§180.103 (a)]	  No22	4271280123

 - Grapes	50 [§180.103 (a)]	No	00046914 00070201 00090988 00098726
00128355 0015960120 0016203724 4018981115 4018981215 4074540521
4225420210

 - Raspberries	25 [§180.103 (a)]	 No22	00070201 4271280123

 - Strawberries	25 [§180.103 (a)]	No	00046914 00070201 00090988
00117088 00128355 0015960720 4018982215 4074540821

4348970125

Tree Nuts Group

	 - Almonds	2 [§180.103 (b)]	No	00070201 00090988 00098804 00098811
00128355 0015959620 0016203724 4018980215 4074540221

 - Almond hulls	100 [§180.103 (b)]	No	00070201 00090988 00098804
00098811 00128355 0015959620 0016203724 4018980215 4074540221

Cereal Grains Group

	 - Corn, sweet	2 [§180.103 (a)]	No	00003025 00045176 00070201 00128355
GS120-039 4018980915 4114910316 4130610117 4130610217 4146840118

Miscellaneous Commodities

	 - Cottonseed	2 [§180.103 (a)]	No	00002928 00003025 00070201 00128355
GS120-039 4018982015 4114910116 4130610117 4130610217 4146840118

	860.1520:  Magnitude of the Residue in Processed Food/Feed

	 - Apples	

	No	00098789 0015959720

4229600310 4018980415 4256310210

 - Grapes	50 (Raisins) [§185.500]

	No26	00128355 0015960120 0016203724 4018981215 4229600410 4256310110

 - Plums/Prunes

No	4018981715

860.1480:  Magnitude of the Residue in Meat, Milk, Poultry, and Eggs

	 - Cattle, hogs	0.05 (fat, meat, and mbyp)

[§180.103 (a)]

	No27	00025125 00035246 00035248 00045178 00096910 00098751 00098808
00098810 00104753 4001050115 4387560310

171-5:  Reduction of Residues

No	0015959520 0015959620 0015959720 0015959920 0015960120 0015960520 
0015960620 0015960720 0016203720

860.1850:  Rotational Crops (Confined)

No	4140400128 4237840128

860.1900:  Rotational Crops (Field)

No

	

1	These references were reviewed in the Residue Chemistry Science
Chapter of the Reregistration Standard dated 3/6/86.  Otherwise,
references were reviewed as noted.

2	The following labels must be revised to include a maximum annual use
rate and pre-harvest interval: 66330-23 and -27.  The label must specify
that the annual use rate includes any post-harvest sprays.  The
directions for post-harvest dip for apples, cherries, and pears must be
modified on label 66330-23.  The feeding restriction for almond hulls
must be removed from 66330-23 because HED does not consider such a
restriction to be practical.

3	CBRS Nos. 6525/6526, 10/2/90, R. Perfetti.

4	CBRS No. 7583, DP Barcode D160608, 9/11/91, R. Perfetti.

5	CBRS No. 9135, DP Barcode D172317, 4/15/92, P. Deschamp.

6	CBRS No. 14006, DP Barcode D205450, 11/30/94, C. Olinger.

7	CBRS No. 11262, DP Barcode D187280, 2/12/93, C. Olinger.

8	CBRS No. 11936, DP Barcode D191630, 2/17/94, C. Olinger.

9	Zeneca (formerly ICI) method No. 166 for quantifying THPI meat and
milk is adequate for use in enforcement (CBRS No. 9877, DP Barcode
D178079, 6/22/92, C. Olinger).

10	Sufficient storage stability data are available to support the
residue data for milk.  THPI residues are stable in animal tissues for 3
years when results are corrected for concurrent method recoveries
(D214345, D222419; C. Olinger, 5/30/96). No additional storage stability
data are required for animal commodities.

11	CBRS No. 4204, 12/19/89, L. Propst.

12	CBRS No. 5148, 5/31/89, L. Cheng.

13	CBRS No. 6995, DP Barcode D155338, 6/26/91, C. Olinger.

14	CBRS No. 12183, DP Barcode D192936, 5/10/94, C. Olinger.

15	CBRS No. 2317, 4/22/88, N. Gray.

16	CBRS No. 5589, 10/6/89, C. Olinger.

17	CBRS No. 6142, 1/29/90, C. Olinger.

18	CBRS No. 6691, 7/30/90, C. Olinger.

19	CBRS No. 6055, 12/18/89, J. Smith.

20	CBRS No. 953, 7/21/86, L. Bradley.

21	CBRS No. 4203, 12/19/89, L. Propst.

22	CBRS No. 11071, DP Barcode No. D186008, 4/25/94, C. Olinger. Data
from a minimum of two additional field trials were required for
reregistration of captan on caneberry subgroup. Tolerance will be
established for caneberry  and individual tolerances revoked (C.
Olinger, CBRS No. 13214, DP Barcode D199377, 3/29/94). Data are
available to support the establishment of a caneberry tolerance and
revocation of individual tolerances (T. Morton, D234270, 3/16/99).

23	Data are available to support the 24C label (D. Davis, CBTS Nos.
11712/11716, DP Barcodes D190127 and D190128, 5/6/93; CBTS Nos.
11890/11891, DP Barcodes D191396 and D191398, 6/1/93); and CBTS Nos.
12097/12098, DP Barcodes D192518 and D192519, 6/29/93).

24	CBRS No. 1334, 9/16/86, L. Bradley.

25	CBRS No. 14715, 6/15/95, C. Olinger. No additional field trials are
required to support the reregistration of strawberry. The tolerance can
be reassessed at 25 ppm.

26	CBRS No. 16181, 11/14/95, C. Olinger.

27	Tolerance increases for animal products should be proposed for
cattle, goats, sheep, horses and hogs:  meat, 0.20 ppm;  meat
by-products, 0.30 ppm;  and fat, 0.15 ppm.  A tolerance for milk must be
proposed at 0.10 ppm.  The tolerance for animal commodities should be
expressed as captan and tetrahydrophthalimide, measured as
tetrahydrophthalimide.

28	CBRS No. 13457, DP Barcode D201033, 7/26/94, S. Funk.

29	CBRS No. none, DP Barcode D234270, 3/16/99,  T. Morton.

TOLERANCE REASSESSMENT SUMMARY

Based on the metabolism data in plants and animals for captan, the HED
Metabolism Committee (4/12/94 and 9/4/97) has determined that the
tolerance expression for meat and milk should include both the parent,
captan and the metabolite THPI.  The tolerance expression for plants,
based on captan per se only, should remain unchanged.

Tolerances for plant and animal commodities currently listed in 40 CFR
§180.103(a) are for residues of captan per se.  This tolerance
definition is to be retained for plant commodities; a separate tolerance
definition is appropriate for livestock commodities.  The tolerance
expression for residues in livestock commodities should be "the combined
residues of captan and its metabolite THPI...".  CBRS recommends that
tolerances for livestock commodities be removed from 40 CFR §180.103(a)
and placed in a new 40 CFR §180.103 © under the revised tolerance
expression.

Tolerances are required to cover the seed treatment uses on the
following crops for which there are currently no established tolerances:
 alfalfa, barley (grain, forage, and straw), clover, corn (field),
cotton forage, flax (seed and straw), grasses (forage and hay),
lespedeza, oats (grain, forage, and straw), okra, peanuts and peanut
hay, radish roots, radish tops, rape seed, rape forage, rape greens, rye
(grain, forage, and straw), safflower, sesame, sunflower (seed and
forage), sorghum (grain, forage and fodder), sugar beet roots, sugar
beet tops, Swiss chard, trefoil, and wheat (grain, forage, and straw).

Adequate data are available to assess the established tolerances for
captan residues in meat, fat, and meat byproducts of cattle and hogs. 
The expression of these tolerances should be changed to "the combined
residues of captan and its metabolite THPI..."  These tolerances should
be deleted from 40 CFR §180.103(a) and placed in a separate section, 40
CFR §180.103(c).  Tolerances should be added to this section for milk
and the meat, fat, and meat byproducts of goats, horses, and sheep.  HED
recommends the following tolerance levels for cattle, goats, sheep,
horses and hogs:  meat, 0.20 ppm; meat by-products, 0.30 ppm; fat, 0.15
ppm; and milk, 0.1 ppm.

Tolerances are not required for eggs and the meat, fat, and meat
byproducts of poultry.

The established tolerances for residues of captan in/on avocados,
celery, garlic, leeks, mangoes, shallots, and taro should be revoked as
there are no registered uses of captan on these crops.

The individual tolerances for blackberry, dewberry, and raspberry should
be revoked and a tolerance for the subgroup caneberry should be
established at 25 ppm (D234270, 3/16/99,  T. Morton).

Tolerances listed in 40 CFR §180.103(b) are for residues of captan per
se and are established on an interim basis.  HED recommends that
tolerances listed in 40 CFR §180.103(b) for almonds, almond hulls,
beans dry, beans succulent, and potatoes be moved to 40 CFR §180.103(a)
at their respective reassessed tolerance levels.

The food additive tolerance listed in 40 CFR §185.500 for washed
raisins is for residues of captan per se.  Captan does not concentrate
in washed raisins so therefore, the tolerance should be revoked.  HED
had previously recommended for revocation of the raisin tolerance in  40
CFR §185.500 (C. Olinger; 11/14/95; D219159).

Table C.  Tolerance Reassessment Summary for Captan

Commodity	Current Tolerance

(ppm)	Tolerance

Reassessment (ppm)	Comment/Correct Commodity Definition

Tolerances listed under 40 CFR §180.103 (a)

	Apples	25	25

	Apricots	50	10

	Avocados	25	Revoke	No registered uses exist

Beet, greens	100	Revoke	Tolerance will be established for crop group in
40 CFR §180.103  (b)

Beet (roots)	2	Revoke	Tolerance will be established for crop group in 40
CFR §180.103  (b)

Blackberry

	25

	Revoke	Tolerance to be established for caneberry

Blueberries (huckleberries)	25	40

	Broccoli	2	Revoke	Tolerance will be established for crop group in 40
CFR §180.103  (b)

Brussels sprouts	2	Revoke	Tolerance will be established for crop group
in 40 CFR §180.103  (b)

Cabbage	2	Revoke	Tolerance will be established for crop group in 40 CFR
§180.103  (b)

Caneberry

25	Tolerance will be established for crop group in 40 CFR §180.103  (a)

Cantaloupes	25	Revoke	Tolerance will be established for crop group in 40
CFR §180.103  (b)

Carrots	2	Revoke	Tolerance will be established for crop group in 40 CFR
§180.103  (b)

Cattle, fat

Cattle meat

Cattle, mbyp	0.05

0.05

0.05	0.15

0.20

0.30	Move to 40 CFR §180.103  (c)

Cauliflower	2	Revoke	Tolerance will be established for crop group in 40
CFR §180.103  (b)

Celery	50	Revoke	No registered uses exist

Cherries	100	50

	Collards	2	Revoke	Tolerance will be established for crop group in 40
CFR §180.103  (b)

Corn, sweet (K+  CWHR)	2	Revoke	Tolerance will be established for crop
group in 40 CFR §180.103  (b)

Cottonseed	2	0.05	Move to 40 CFR §180.103(b)/Cotton, seed

Cucumbers	25	Revoke	Tolerance will be established for crop group in 40
CFR §180.103  (b)

Dewberry	25	Revoke	Tolerance to be established for caneberry

Eggplants	25	Revoke	Tolerance will be established for crop group in 40
CFR §180.103  (b)

Garlic	25	Revoke	No registered uses exist

Grapes	50	25

	Hogs, fat

Hogs, meat

Hogs, mbyp	0.05

0.05

0.05	0.15

0.20

0.30	Move to 40 CFR §180.103 (c)

Honeydew melons	25	Revoke	Tolerance will be established for crop group
in 40 CFR §180.103  (b)

Kale	2	Revoke	Tolerance will be established for crop group in 40 CFR
§180.103  (b)

Leeks	50	Revoke	No registered uses exist

Lettuce	100	Revoke	Tolerance will be established for crop group in 40
CFR §180.103  (b)

Mangoes	50	Revoke	No data have been submitted to support use

Muskmelons	25	Revoke	Tolerance will be established for crop group in 40
CFR §180.103  (b)

Mustard greens	2	Revoke	Tolerance will be established for crop group in
40 CFR §180.103  (b)

Nectarines	50	25

	Onions, dry bulb	25	Revoke	Tolerance will be established for crop group
in 40 CFR §180.103  (b)

Onions, green	50	Revoke	Tolerance will be established for crop group in
40 CFR §180.103  (b)

Peaches	50	15

	Pears	25	25

	Peas, dry	2	Revoke	Tolerance will be established for crop group in 40
CFR §180.103  (b)

Peas, succulent	2	Revoke	Tolerance will be established for crop group in
40 CFR §180.103  (b)

Plums (fresh prunes)	100	10

	Peppers

Pimentos	25

25	Revoke	Tolerance will be established for crop group in 40 CFR
§180.103  (b)

Pumpkins	25	Revoke	Tolerance will be established for crop group in 40
CFR §180.103  (b)

Raspberry	25	Revoke	Tolerance to be established for caneberry

Rutabagas (roots)	2	Revoke	Tolerance will be established for crop group
in 40 CFR §180.103  (b)

Shallots	50	Revoke	No registered uses exist

Soybeans, dry	2	Revoke	Tolerance will be established for crop group in
40 CFR §180.103  (b)

Soybeans, succulent	2	Revoke	Tolerance will be established for crop
group in 40 CFR §180.103  (b)

Spinach	100	Revoke	Tolerance will be established for crop group in 40
CFR §180.103  (b)

Squash, summer	25	Revoke	Tolerance will be established for crop group in
40 CFR §180.103  (b)

Squash, winter	25	Revoke	Tolerance will be established for crop group in
40 CFR §180.103  (b)

Strawberries	25	25

	Taro (corn)	0.25	Revoke	No registered uses exist

Tomatoes	25	Revoke	Tolerance will be established for crop group in 40
CFR §180.103  (b)

Turnip, greens	2	Revoke	Tolerance will be established for crop group in
40 CFR §180.103  (b)

Turnips, roots	2	Revoke	Tolerance will be established for crop group in
40 CFR §180.103  (b)

Watermelons	25	Revoke	Tolerance will be established for crop group in 40
CFR §180.103  (b)

Tolerances listed under 40 CFR §180.103 (b)

	Almonds	2	0.25	Move to 

40 CFR §180.103 (a)

Almond hulls	100	75	Move to 

40 CFR §180.103 (a)

Beans, dry	25	Revoke	Tolerance will be established for crop group

Beans, succulent	25	Revoke	Tolerance will be established for crop group 

Potatoes	25	Revoke	Tolerance will be established for crop group

Tolerances required under 40 CFR §180.103 (b) - Redefined

	Brassica Leafy Vegetables	--	0.05	Seed treatment only

Bulb Vegetables	--	0.05	Seed treatment only

Cereal Grains	--	0.05	Seed treatment only

Cereal Grain Forage, Fodder, and Straw	--	0.05	Seed treatment only

Cucurbit Vegetables	--	0.05	Seed treatment only

Dill, seed	--	0.05	Seed treatment only

Foliage of Legume Vegetables	--	0.05	Seed treatment only

Flax, seed	--	0.05	Seed treatment only

Flax, straw	--	0.05	Seed treatment only

Fruiting Vegetables	--	0.05	Seed treatment only

Grasses (Forage and Hay)	--	0.05	Seed treatment only

Leafy Vegetables (except Brassica)	--	0.05	Seed treatment only

Leaves of Root and Tuber Vegetables	--	0.05	Seed treatment only

Legume Vegetables (succulent and dried)	--	0.05	Seed treatment only

Non-Grass Animal Feeds (Forage, Fodder, Straw, and Hay)	--	0.05	Seed
treatment only

Okra	--	0.05	Seed treatment only

Peanuts	--	0.05	Seed treatment only

Peanut hay	--	0.05	Seed treatment only

Rape, seed	--	0.05	Seed treatment only

Rape, forage	--	0.05	Seed treatment only

Rape, greens	--	0.05	Seed treatment only

Root and Tuber Vegetables	-	0.05	Seed treatment only

Safflower seed	--	0.05	Seed treatment only

Sesame seed	--	0.05	Seed treatment only

Sunflower, seeds	--	0.05	Seed treatment only

Sunflower, forage	--	0.05	Seed treatment only

Tolerances required under 40 CFR §180.103 (c)

	Cattle, fat	0.05	0.15

	Cattle, mbyp 	0.05	0.30

	Cattle, meat	0.05	0.20

	Goats, fat	--	0.15

	Goats, mbyp	--	0.30

	Goats, meat	--	0.20

	Hogs, fat	0.05	0.15

	Hogs, mbyp	0.05	0.30

	Hogs, meat	0.05	0.20

	Horses, fat	--	0.15

	Horses, mbyp	--	0.30

	Horses, meat	--	0.20

	Milk	--	0.10

	Sheep, fat	--	0.15

	Sheep, mbyp	--	0.30

	Sheep, meat	--	0.20	

Food Additive Tolerances Listed Under 40 CFR §185.500

	Washed raisins	50	Revoke	No concentration in washed raisins.

Refer to Table C for modifications in commodity definitions and
recommended tolerance revisions and Table D for recommendations for
harmonizing U.S. tolerances with Codex MRLs.

	●	The established tolerance levels for apple, pear, and strawberry
are adequate and should remain.

	●	The established tolerances for almonds, almond hulls, apricots,
cherries, grapes, nectarines, peaches, and plums can be lowered due to
revised, more restrictive use patterns.

	●	The established tolerances for beans (dry), beans (succulent), beet
greens, beet roots, cantaloupes, cucumbers, eggplants, honeydew melons,
kale, lettuce, muskmelons, onions, peas (dry), peas (succulent),
peppers, pimentos, pumpkins, spinach, squash (summer), squash (winter),
and watermelons should be lowered to 0.05 ppm.  All uses except seed
treatments on these crops have been canceled.  The recommended 0.05 ppm
level represents nondetectable residues of captan. 

●	The established 2 ppm tolerances for captan residues in/on broccoli,
Brussels sprouts, cabbage, carrots, cauliflower, collards, corn (sweet,
K+CWHR), cottonseed, mustard greens, rutabagas, soybeans (dry), soybeans
(succulent), turnip tops, and turnip roots from seed treatment use
should be lowered to 0.05 ppm to represent nondetectable captan
residues.

	●	The established tolerance levels for blueberry of 25 ppm should be
increased to 40 ppm based on registered use patterns in the U.S.

CODEX HARMONIZATION

Several maximum residue limits (MRLs) for captan have been established
by Codex in various commodities.  The captan residues regulated by Codex
and the U.S. are equivalent.  The Codex MRLs defined in terms of captan
per se and corresponding U.S. tolerances are listed in Table D.

	

Table D.	Codex MRLs and applicable U.S. tolerances.  Recommendations for
compatibility are based on conclusions following reassessments of U.S.
tolerances (see Table C).

Commodity	MRL (mg/kg)1	U.S. Tolerance (ppm)	Recommendation

Apple	25	25

	Blueberries	20	40

	Citrus fruits	152	N/A

	Dried grapes	52	50

 (washed raisins)	Previous recommendation for revocation for washed
raisin tolerance

Peach	15	50	Decrease U.S. tolerance

Pear	25	25

	Strawberry	20	25

	Tomato	15	0.05	U.S. tolerance to be revoked; tolerance to be
established for Fruiting Vegetables/Seed Treatment only

	1All captan MRLs are final (CXL).

2JMPR 1990 had proposed to withdraw the CXL in view of no expected uses.

The following conclusions can be made regarding efforts to harmonize the
U.S. tolerances with the Codex MRLs:

	○	Compatibility between U.S. tolerances and Codex MRLs exists for
apples and pears.

	○	The level of the U.S. tolerances should be decreased to achieve
compatibility with the Codex MRLs for peaches (from 25 ppm to 15 ppm). 
The available residue data support the decreased tolerance levels.

	○	HED had previously recommended for revocation of the raisin
tolerance in  40 CFR §185.500 (C. Olinger; 11/14/95; D219159).  The
tolerance cannot be lowered to 5 ppm to achieve compatibility with the
Codex MRL for dried grapes.

	○	The U.S. tolerance of 25 ppm for strawberries is based on
registered use patterns in the U.S. and cannot be lowered to 20 ppm to
achieve compatibility with the Codex MRL of 20 ppm.

	○	The U.S. reassessed tolerance of 40 ppm for blueberries is based on
registered use patterns in the U.S. and cannot be lowered to 20 ppm to
achieve compatibility with the Codex MRL of 20 ppm.

	○	No questions of compatibility exist with respect to  commodities
where:  (I) no Codex MRLs have been established but U.S. tolerances
exist; or (ii) Codex MRLs have been established but U.S. tolerances do
not exist.

			

DIETARY EXPOSURE REASSESSMENT tc "DIETARY EXPOSURE REASSESSMENT" 

The plant metabolism data for captan are adequate.  Sufficient residue
data are available to reassess all tolerances for plant commodities with
the exception of the caneberries (blackberries, dewberries, and
raspberries) and strawberries.  The existing data are sufficient to
estimate that the tolerances for these commodities are not likely to
require modification.

Tolerances are not required for poultry commodities.

HED has revised the anticipated residue calculations for captan and THPI
in light of canceled uses, recently submitted residue data, and the most
recent FDA monitoring data.  The risk assessment will involve captan
only for raw plant and processed plant commodities and captan and THPI
for meat and milk.  Captan and THPI residues in livestock feed items
will be considered when estimating the livestock dietary burden.

The anticipated residue values are the best estimates HED can provide
using the residue data available at the time of the RED.  These values
have an inherent uncertainty associated with the variations in
analytical methods, geographical representation of field trials,
seasonal variation of residue levels, and other factors.

AGENCY MEMORANDA CITED IN THIS DOCUMENT tc "AGENCY MEMORANDA CITED IN
THIS DOCUMENT" 

CBRS No.:	953

Subject:		Captan Residue Reduction Data Submitted in Response to
04/29/85 DCI Letter.  Accession No. 262770.  RCB No. 953

From:		L.M. Bradley

To:		C. Langley, A. Rispin, E. Wilson, and B. Briscoe

Dated:		7/21/86

MRID(s):	00159595-00159608

CBRS No.:	1334

Subject:		Captan.  Addendum to Residue Reduction Data Submitted in
Response to 04/29/85 DCI Letter.  Accession No. 263843.  RCB No. 1334.

From:		L.M. Bradley

To:		C. Monroe, A. Rispin, E. Wilson, and B. Briscoe

Dated:		9/19/86

MRID(s):	00162037

CBRS No.:	2317

Subject:		Captan - Addendum to Registration Standard.  RCB No. 2317. 
MRID Nos. 401898-02 through - 24 and 400105-01.

From:		N.S. Gray

To:		J. Dizikes and E. Wilson

Dated:		4/22/88

MRID(s):	40010501 and 40189802-40189824

CBRS No.:	4203

Subject:		Residue Data Reflecting Aerial Versus Ground Spray
Applications of Captan on Foliar Crops

From:		L.S. Propst

To:		E.M. Wilson

Dated:		12/19/89

MRID(s):	40475401-40745409

CBRS No.:	4204

Subject:		Captan - Storage Stability Studies for the Captan Registration
Standard

From:		L.S. Propst

To:		E.M. Wilson

Dated:		12/19/89

MRID(s):	40752301

CBRS No.:	5148

Subject:		239-1246.  Captan on Blueberries.  MRID # 410391-01.  DEB #
5148.

From:		L. Cheng

To:		R. Mountfort

Dated:		5/31/89

MRID(s):	41039101

CBRS No.:	5589

Subject:		Residue Data Review for Corn, Soybean, Beet, and Spinach Seed
Treatments with Captan, DEB No. 5589, EPA No. 239-1246, MRID Nos.
411491-01 through -04

From:		C.L. Olinger

To:		E. Wilson

Dated:		10/6/89

MRID(s):	41149101-41149104

CBRS No.:	6142

Subject:		Residue Data Review for Soybean and Wheat Seed Treatments with
Captan, Record No. 256461;  ID No. 10182-293; DEB No. 6142; MRID Nos.
413061-01 and -02

From:		C.L. Olinger

To:		J. Miller

Dated:		1/29/90

MRID(s):	41306101 and 41306102

CBRS No.:	6691

Subject:		Addendum to Residue Data for Captan Seed Treatments; EPA Reg.
No. 10182-293; MRID No. 41468401; DEB No. 6691

From:		C.L. Olinger

To:		J. Miller

Dated:		7/30/90

MRID(s):	41468401

CBRS Nos.:	6525 and 6526

Subject:		Chevron Chemical Co.: Response to the Captan Reregistration
Standard: Residue Chemistry Requirements (No MRID #'s 406580-02, -03,
-04, -05, and -06, and 413930-01, 414069-01, 413865-01, DEB #'s 6525 and
6526.)

From:		R.B. Perfetti

To:		R. Engler and L. Rossi

Dated:		10/2/90

MRID(s):	40658002-40658006, 41386501, 41393001, and 41406901

CBRS No:	6995

DP Barcode:	D155338

Subject:		Captan - Storage Stability Studies for the Captan Registration
Standard and Follow-Up to Seed Treatment Residue Data; MRID No.
411576-01; Branch No. 6995; DP Barcode No. 155338

From:		C.L. Olinger

To:		C. Peterson

Dated:		6/26/91

MRID(s):	41157601

CBRS No.:	7583

DP Barcode:	D160608

Subject:		Captan - Registrant's Response to Residue Chemistry Data
Requirements

From:		R. Perfetti

To:		R. Engler and L. Rossi

Dated:		6/26/91

MRID(s):	41746001

CBRS No.	9135

DP Barcode:	D172317

Subject:		Reregistration of Captan.  Case No. 120.  Qualitative Nature
of the Residue in Plants

From:		P. Deschamp

To:		L. Rossi/C. Peterson

Dated:		4/15/92

MRID(s):	42109601

CBRS No.	9902, 10668, and 11105

DP Barcode:	D178351 and D183051

Subject:		Reregistration of Captan:  Magnitude of Residue in Meat, Milk,
Poultry, and Eggs;  Magnitude of Residue in Apples, Grapes, and their
Processed Products

From:		C. Olinger

To:		L. Rossi

Dated:		5/20/94

MRID(s):	42252201, 42252202, 42296001, 42296002, 42296003, 42296004,
42563101 and 42563102

CBRS No.	9877

DP Barcode:	D178079

Subject:		Reregistration of Captan:  Method Validation Request

From:		C. Olinger

To:		D. Marlow

Dated:		6/22/92

MRID(s):	None

CBRS No.	10477

DP Barcode:	D182080

Subject:		Reregistration of Captan:  Use on Strawberries

From:		C. Olinger

To:		L. Rossi

Dated:		9/16/92

MRID(s):	None

CBRS No.	11071

DP Barcode:	D186008

Subject:		Reregistration of Captan:  Use on Peaches and Nectarines

From:		C. Olinger

To:		L. Rossi

Dated:		4/25/94

MRID(s):	None

CBRS No.	11262

DP Barcode:	D187280

Subject:		Reregistration of Captan:  Animal Metabolism Study Interim
Report

From:		C. Olinger

To:		L. Rossi

Dated:		2/12/93

MRID(s):	42568801

CBTS No.	11712/11716

DP Barcode:	D190127/D190128

Subject:		WA920011, WA920012, Section 24© Captan on Raspberries and
Blackberries

From:		D. Davis

To:		D. Kenney/Joanne Miller

Dated:		5/6/93

MRID(s):	42712801

CBTS No.	11890/11891

DP Barcode:	D191396/D191398

Subject:		WA920011, WA920012, Section 24© Captan on Raspberries and
Blackberries

From:		D. Davis

To:		D. Kenney/Joanne Miller

Dated:		6/1/93

MRID(s):	42712801

CBTS No.	12097/12098

DP Barcode:	D192518/D192519

Subject:		WA920011, WA920012, Section 24© Captan on Raspberries and
Blackberries

From:		D. Davis

To:		D. Kenney/Joanne Miller

Dated:		6/29/93

MRID(s):	42712801

CBRS No.	11936

DP Barcode:	D191630

Subject:		Reregistration of Captan:  Metabolism in Laying Hens

From:		C. Olinger

To:		L. Rossi

Dated:		2/17/93

MRID(s):	42756401

CBRS No.	13214

DP Barcode:	D199377

Subject:		Reregistration of Captan:  Raspberry Magnitude of Residue Data

From:		C. Olinger

To:		L. Rossi

Dated:		3/29/94

MRID(s):	43086601

CBRS No.	12183

DP Barcode:	D192936

Subject:		Reregistration of Captan:  Storage Stability Issues

From:		C. Olinger

To:		L. Rossi

Dated:		5/10/94

MRID(s):	42803901

CBRS No.	13650

DP Barcode:	D202998

Subject:		Use of Captan on Strawberries

From:		C. Olinger

To:		J. Miller

Dated:		5/20/94

MRID(s):	None

CBRS No.	None

DP Barcode:	None

Subject:		The Metabolism Committee Meetings Held on February 22 and
March 1, 1994; Captan Plant and Animal Metabolism

From:		C. Olinger

To:		The Metabolism Committee; Health Effects Division

Dated:		4/1/94

MRID(s):	None

CBRS No.	14006

DP Barcode:	D205450

Subject:		Addendum to Captan RED: Captan Livestock Metabolism

From:		C. Olinger

To:		Linda Propst

Dated:		11/30/94

MRID(s):	43266701, 43266702

	

CBRS No.	15460, 17247

DP Barcode:	D214345, D222419

Subject:		Addendum to Captan RED: Registrant Rebuttal and Response to
Previous Reviews

From:		C. Olinger

To:		Paula Deschamp

Dated:		5/30/96

MRID(s):	43584601, 43875603

CBRS No.	17426

DP Barcode:	D228077

Subject:		Addendum to Captan RED: Revisions to Table A of the Residue
Chemistry Chapter 

From:		C. Olinger

To:		John Redden

Dated:		2/5/97

MRID(s):	None

CBRS No.	None

DP Barcode:	D234270

Subject:		Reregistration of Captan: Use of Captan on Raspberries 

From:		T. Morton

To:		K. Rothwell

Dated:		3/16/99

MRID(s):	44227201

MASTER RECORD IDENTIFICATION NUMBERS tc "MASTER RECORD IDENTIFICATION
NUMBERS" 

00002927 Devine, J.M.; Horton, W.E. (1972) Determination of Captan
[N-Trichloromethylmercapto-4-cyclohexene-1,2,-dicarboximide] in
Cottonseed: Report No. 120.  (Unpublished study received on unknown date
under 0F0939; prepared by State Univ. College-Oswego, Lake Ontario
Environmental Laboratory, submitted by Uniroyal Chemical, Bethany,
Conn.; CDL:094582-A)

00002928 Uniroyal Chemical (1972) Residues in PPM: [Vitavax]. 
(Unpublished study received on unknown date under 0F0939; CDL:094582-B)

00003025 Chevron Chemical Company (1977) Residue Chemistry Data to
Support the Label Registration of Orthocide-Vitavax 20-20 Seed
Protectant.  Includes method RM-IF-1 dated Jun 25, 1976 entitled:
Determination of Captan residues in crops.  (Unpublished study received
May 11, 1977 under 239-2458; CDL:230222-A)

00025123 Chevron Chemical Company (1979) Determination of Captafol,
Captan, THPI, and 3-OH THPI in Tissues and Eggs and Determination of
Captan, THPI, 3-OH THPI, and 5-OH THPI in Milk and Cream.  Undated
method nos. RM-6-G-2, RM-1G-1 and RRC-75-32.  (Unpublished study
received Jan 2, 1980 under 239-2211; prepared in cooperation with
Stauffer Chemical Co.; CDL:099190-F)

00025125 Leary, J.B.; Lai, J.C. (1976) Captan-Lactating Dairy Cow
Feeding Study-Residues in Meat.  (Unpublished study received Jan 2, 1980
under 239-2211; submitted by Chevron Chemical Co., Richmond, Calif.;
CDL:099190-H)

00025129 Cheng, H.M. (1976) Metabolism of Carbonyl-14C-difolatan in
Young Tomato and Corn Plants.  (Unpublished study received Jan 2, 1980
under 239-2211; submitted by Chevron Chemical Co., Richmond, Calif.;
CDL:099190-L)

00035246 Haumschild, D.; Wingender, R.J. (1972) Report to American Seed
Trade Association, Inc.: Tissue Residue Study for Captan and
Tetrahydrophthalimide in Crossbred Steers Fed Technical Captan:  IBT No.
J1255.  Includes methods entitled: Determination of Captan and
Determination of Tetrahydrophthalimide (THPI).  (Unpublished study
received Jun 27, 1977 under 3E1367; prepared by Industrial Bio-Test
Laboratories, Inc., submitted by Stauffer

00035248 Taylor, R.E.; Brunhouse, E. (1972) Captan Study for American
Seed Trade Association.  Includes method RM-1E dated May 26, 1972. 
(Unpublished study including letter dated Feb 1, 1973 from J.C. Calandra
to Ron Harris, received Jun 27, 1977 under 3E1367; prepared by Harris
Laboratories, Inc., submitted by Stauffer Chemical Co., Richmond,
Calif.; CDL:096174-D)

00042645 Rappaport, S.H.; Katague, D.B. (1978) Determination of Captan
Residues in Crops by Gas Chromatography.  Method RRC-76-30R dated Mar
27, 1978.  (Unpublished study received Sep 25, 1980 under 0E2427;
prepared by Stauffer Chemical Co., submitted by New Zealand, Ministry of
Agriculture and Fisheries, Wellington, New Zealand; CDL:099651-C)

00042646 New Zealand, Ministry of Agriculture and Fisheries (19??)
Method for the Determination of Captan Residues in Kiwifruit. 
(Unpublished study; CDL:099651-D)

00045174 Haumschild, D.; Wingender, R.J. (1972) Report to American Seed
Trade Association, Inc.: Tissue Residue Study for Captan and
Tetrahydrophthalimide in Crossbred Steers Fed Technical Captan:  IBT No.
J1255.  Includes undated methods entitled: Determination of Captan and
Determination of Tetrahydrophthalimide (THPI).  Prepared by Industrial
Bio-Test Laboratories, Inc.  Unpublished study; 142 p.

00045175 American Seed Trade Association, Incorporated (19??) Analytical
Method Used for Residue Analysis of Captan.  (Unpublished study received
Mar 9, 1967 under 3E1367; CDL:096507-B)

00045176 Wilson, M. (1973) Captan Residue Report: Field Corn Seed. 
(Unpublished study received on unknown date under 3E1367; submitted by
American Seed Trade Association, Inc., Kalamazoo, Mich.; CDL:096507-C)

00045178 American Seed Trade Association, Incorporated (1973) Supplement
to American Seed Trade Association, Inc. Petition #3F1367 for a Captan
Tolerance on Detreated Corn Seed Intended as Feed for Beef Cattle and
Swine.  (Unpublished study including letter dated Apr 25, 1973 from J.C.
McKay to Harold Wright, received on unknown date under 3E1367;
CDL:096507-E)

00045179 Patchett, G.G. (1973) Determination of Tetrahydrophthalamic
acid Residues in Cattle and Hog Tissues.  Method no. WRC 73-38 dated May
17, 1973.  (Unpublished study received on unknown date under 3E1367;
prepared by Stauffer Chemical Co., submitted by American Seed Trade
Association, Inc., Kalamazoo, Mich.; CDL:096507-F)

00045182 American Seed Trade Association, Incorporated (19??)
Determination of Captan Residues on Treated Seed Corn.  Undated method. 
(Unpublished study received Mar 9, 1967 under 3E1367; CDL:096507-J)

00045183 American Seed Trade Association, Incorporated (19??) Method for
Determination of Captan Residue on Corn.  (Unpublished study received
Mar 9, 1967 under 3E1367; CDL:096507-K)

00045184 Kilgore, W.W.; Winterlin, W.; White, R. (1967) Gas
chromatographic determination of Captan residues.  Journal of
Agricultural and Food Chemistry 15(6):1035-1037.  (Also unpublished
submission received on unknown date under 3E1367; submitted by American
Seed Trade Association, Inc., Kalamazoo, Mich.; CDL:096507-L)

00045188 Chevron Chemical Company (1972) Determination of Captan
Residues in Animal Tissues.  Method RM-1E dated May 26, 1972. 
(Unpublished study received on unknown date under 3E1367; submitted by
American Seed Trade Association, Inc., Kalamazoo, Mich.; CDL:096507-Q)

00045189 Wingender, R.J. (1973) Report to American Seed Trade
Association, Inc.:  Results from the Analysis of Hog Tissues for
Tetrahydrophthalimide: IBT No. D2043.  (Unpublished study received Mar
9, 1973 under 3E1367; prepared by Industrial Bio-Test Laboratories,
Inc., submitted by American Seed Trade Association, Inc., Kalamazoo,
Mich.; CDL:096506-F)

00046914 Hensall, GS (1957) Fulton Research Report 1957.  (Unpublished
study received Oct 28, 1957 under unknown admin. no.; submitted by
Chevron Chemical Co., Richmond, Calif.; CDL:119324-A)

00053324 California Spray-Chemical Corporation (1957) Methods of Residue
Analysis of Captan or Fulton.  (Unpublished study received Feb 11, 1958
under unknown admin. no.; submitted by Chevron Chemical Co., Richmond,
Calif.; CDL:119325-A)

00054015 California Spray Chemical Corporation (1960) The Analysis of
Residues of Captan and Fulton.  Method RM-1 dated Apr 4, 1960. 
(Unpublished study received Jul 14, 1972 under 2E1215; submitted by
Interregional Research Project No. 4, New Brunswick, N.J.; CDL:091043-A)

00054016 University of Hawaii (1969) Captan-Taro Residue Study. 
(Unpublished study received Jul 14, 1972 under 2E1215; prepared by
Agricultural Biochemistry Dept., Pesticide Laboratory in cooperation
with Chevron Chemical Co., submitted by Interregional Research Project
No. 4, New Brunswick, N.J.; CDL:091043-B)

00058940 Cheng, H.M. (1980) Metabolism of [Carbonyl-14C]-Captan in a
Lactating Goat: File No. 721.14/Captan.  (Unpublished study received Oct
30, 1980 under 239-533; submitted by Chevron Chemical Co., Richmond,
Calif.; CDL:243629-B) 

00058941 Cheng, H.M. (1980) Degradation Products of
[Carbonyl-14C]-Captan in Apple and Orange Processed Parts: File No.
721.14/Captan.  (Unpublished study received Oct 30, 1980 under 239-533;
submitted by Chevron Chemical Co., Richmond, Calif.; CDL:243629-D) 

00070201 California Spray Chemical Corporation (1957) [Captan
Residues-Various Crops].  (Reports by various sources; unpublished study
received Feb 25, 1957 under PP0124; CDL:090426-J)

00071790 Stauffer Chemical Company (1980) [Residue Data of Various
Chemicals, Including Captan, on Soybeans].  (Compilation; unpublished
study received Dec 12, 1980 under AR 80/24; submitted by state of
Arkansas for Stauffer; CDL:243877-A)

00083100 Pack, DE (1980) Analysis of Soybeans Grown from Seed Treated
with 14C-Captan-Greenhouse Study: File 721.14.  (Unpublished study
received Mar 23, 1981 under 239-2457; submitted by Chevron Chemical Co.,
Richmond, Calif.; CDL:244766-A)

00083393 California Chemical Company (1961) The Determination of and
Differentiation between Residues of Fulton and Captan:  File 740.10. 
Residue method RM-1A dated Jan 31, 1961.  (Unpublished study received on
unknown date under PP0283; CDL:090305-D)

00085525 Petri no, LM (1955) Colorimetric Estimation of Captan Surface
Residue on Fruit Samples: (Adaptation of Method Published in Analytical
Chemistry, July, 1952, Page 1173).  Method dated Mar 21, 1955. 
(Unpublished study received May 1, 1955 under PP0015; prepared by
Stauffer Chemical Co., submitted by California Spray-Chemical Co.,
Richmond, Calif.; CDL:090983-O)

00085526 California Spray-Chemical Company (1954) Determination of
Captan Residues.  (Unpublished study received May 1, 1955 under PP0015;
CDL:090983-P)

00090988 California Spray-Chemical Corporation (1957) The Results of
Tests on the Amount of Residue Remaining, Including a Description of the
Analytical Method Used:  [Captan].  (Compilation; unpublished study
received on unknown date under PP0124; CDL:090432-D) 

00090989 Curtis & Tompkins, Limited (1955) Letter sent to LW Hazleton
dated Mar 30, 1955: Determination of captan and tetrahydrophthalimide
residues on apples, concerning lab. no. 55d40.  (Incomplete; unpublished
study received Apr 18, 1957 under PP0124; submitted by California
Spray-Chemical Corp., Richmond, Calif.; CDL:090432-E)

00096901 Crassly, J. (1970) The Fate of Defoliation in a Lactating
Ruminant (Goat): File No. 721.14.  (Unpublished study received Jun
9,1977 under 239-2211; submitted by Chevron Chemical Co., Richmond,
Calif.; CDL:096157-C)

00096908 Cheng, H.M. (1979) Metabolism of Carbonyl 14C Captafol in a
Lactating Goat: File No. 721.14.  (Unpublished study received Jan 2,
1980 under 239-2211; submitted by Chevron Chemical Co., Richmond,
Calif.; CDL:099191-G)

00096910 Hillebrecht, W.R.; Riggs, R.L. (1977) Captan Milk Residue Study
in Lactating Dairy Cattle.  (Unpublished study received Jan 2, 1980
under 239-2211; prepared by Stauffer Chemical Co., submitted by Chevron
Chemical Co., Richmond, Calif.; CDL:099191-I)

00096978 Abell, J.; Moore, J.E. (1967) Attempts To Demonstrate the
Translocation of Defoliation and Orthocide:  File No. 721.13. 
(Unpublished study received May 30, 1978 under 239-2211; submitted by
Chevron Chemical Co., Richmond, Calif.; CDL:234046-AB)

00096982 Chevron Chemical Company (1979) Residue Data Sheet: [Soybeans]:
 Test No. T-4546.  (Compilation; unpublished study received Mar 28, 1979
under 239-2369; CDL:237912-A)

00097622 Stauffer Chemical Company (1976) Captan 80-WP on Soybeans:
Summary of Crop Residue Data.  (Compilation; unpublished study received
1976 under 476-EX-77; CDL:228997-A)

00098708 Chevron Chemical Company (1950) [Residue Studies of Orthocide
406 on Tomatoes].  (Compilation; unpublished study received Mar 21, 1951
under 239-533; CDL:001157-B)

00098709 Chevron Chemical Company (1950) [Residue Studies of Orthocide
406 on Various Vegetables].  (Compilation; unpublished study received
Mar 21, 1951 under 239-533; CDL:001157-C)

00098710 Davis, D.L. (1950) Residue Analysis-SR-406: [Snap Beans]. 
(Unpublished study received Mar 21, 1951 under 239-533; submitted by
Chevron Chemical Co., Richmond, Calif.; CDL:001157-D)

00098711 Davis, D.L. (1950) Residue Analysis--SR-406: [Apples]. 
(Unpublished study received Mar 21, 1951 under 239-533; submitted by
Chevron Chemical Co., Richmond, Calif.; CDL:001157-E)

00098716 Kohn; G.K. (1954) Captan Residues on Potatoes.  (Unpublished
study received Jun 2, 1954 under 239-533; submitted by Chevron Chemical
Co., Richmond, Calif.; CDL:001163-A) 

00098720 Chevron Chemical Company (1952) Analysis of Fruits and
Vegetables for Captan Residues.  (Unpublished study received Mar 22,
1955 under 239-533; CDL:001177-A)

00098722 Kohn, G.K. (1958) Letter sent to GS Hensall dated May 21, 1958:
 Captan residues: postharvest treatment.  (Unpublished study received
Jun 20, 1958 under 239-533; submitted by Chevron Chemical Co., Richmond,
Calif.; CDL:001194-A)

00098726 Chevron Chemical Company (1950) [SR-406: Residues in Various
Crops].  (Compilation; unpublished study received Oct 10, 1951 under
239-1102; CDL:001257-B)

00098731 Kittleson, A.R. (1952) Colorimetric determination of
N-trichloro-methiotetrahydrophthalimide.  Analytical Chemistry
24:1173-1174.  (Also unpublished submission received Feb 21, 1973 under
1486-20; submitted by Ferro Corp., Bedford, Ohio; CDL:006427-C)

00098747 Makhteshim Chemical Works Limited (1969) Merpan: Residue
Analysis:  DS 13.51.11.  (Unpublished study received Apr 17, 1972 under
11678-1; CDL:026318-B)

00098751 Chevron Chemical Company (1954) Captan Residues in Meat. 
(Unpublished study received May 5, 1954 under 239-656; CDL:027009-B)

00098784 Interregional Research Project Number 4 (1976) [Determination
of Captan Pesticide in or on Taro Leaves].  (Compilation; unpublished
study received Jul 11, 1977 under 7E1982; CDL:097592-A)

00098786 Mitoma, C. (1972) Pilot Study to Determine the Nature and
Magnitude of the Residues from Ingestion of Captan in a Ruminating
Animal:  SRI Project LSC-1697.  (Unpublished study received Mar 7, 1977
under 239-2457; prepared by Stanford Research Institute, submitted by
Chevron Chemical Co., Richmond, Calif.; CDL:096129-B)

00098789 Chevron Chemical Company (1976) [Captan Residue
Analyses-Apples].  (Compilation; unpublished study, including test nos.
T-3513 and T-3514, received Mar 7, 1977 under 239-2457; CDL:096129-H)

00098790 DeBaun, J.R.; Gruwell, L.A.; Menn, J.J. (1975) The Fate of
Captan [Carbonyl-14C] on Field-grown Apple Trees:  MRC-B-44.  Rev. 
(Unpublished study received Mar 7, 1977 under 239-2457; prepared by
Stauffer Chemical Co., submitted by Chevron Chemical Co., Richmond,
Calif.; CDL:096129-I)

00098804 California Spray-Chemical Corporation (1961) Residue Data
Sheet:  [Almonds]: Test No. T-239.  (Unpublished study received Jan 24,
1962 under 239-533; submitted by Chevron Chemical Co., Richmond, Calif.;
CDL:121209-A)

00098808 Chevron Chemical Company (1957) [Captan: Residues in Cattle]. 
(Compilation; unpublished study, including cattle progress report 247,
received May 9, 1961 under unknown admin. no.; CDL:121212-C)

00098810 Cripps, J.M. (1957) Letter sent to California Spray-Chemical
Corporation dated Feb 13, 1957: Captan residues-chicken eggs, breasts,
thighs and livers.  (Unpublished study received May 9, 1961 under
unknown admin. no.; submitted by Chevron Chemical Co., Richmond, Calif.;
CDL:121212-G)

00098811 Chevron Chemical Company (1957) [Captan Residues in Almonds]. 
(Compilation; unpublished study received May 9, 1961 under unknown
admin. no.; CDL:121212-H)

00098817 Chevron Chemical Company (1957) [Residue Studies of Captan on
Raisins].  (Compilation; unpublished study received Jun 25, 1957 under
239-104; CDL:121282-A)

00098818 Pennwalt Corporation (19??) Captan Residue on Cantaloupes
Treated with Decco Salt No. 10.  (Unpublished study received Aug 5, 1957
under unknown admin. no.; CDL:121594-A)

00098831 Tagawa, H.; Yamaguchi, Y. (1970) Persistence of Captan and
Defoliation in Soil and Their Absorption by Tobacco Plants from Soil.  A
translation of:  [Without Title].  Bulletin of the Hatano Tobacco
Experiment Station, Yokohama, Kangagwa, Japan 73:353.  (Unpublished
study received Jan 4, 1978 under 239-1246; submitted by Chevron Chemical
Co., Richmond, Calif.; CDL:232569-H).

00098894 Chevron Chemical Company (1979) [Analyses for Orthocide Plus in
Potatoes].  (Compilation; unpublished study received Sep 18, 1979 under
239-2474; CDL:241047-A)

00104753 McKay, J.C. (1973) Letter sent to Harold Wright dated Mar 2,
1973 [Determinations for residues of tetrahydrophthalamic acid-Captan]. 
(Unpublished study received Mar 9, 1973 under 3E1367; prepared by
Stauffer Chemical Co., submitted by American Seed Trade Association,
Inc., Kalamazoo, Mich.; CDL:096506-D)

00106602 Stauffer Chemical Company (1975) Summary of Crop Residue Data
Supporting Registration of Captan: Imidan 16:12-WP.  (Compilation;
unpublished study received Mar 21, 1975 under 476-2172; CDL:028453-D)

00117087 Maddy, K.; Kahn, C.; Riddle, L.; et al. (1977) A Breakdown
Study of Captan ... on Strawberry Foliage and Fruit in Ventura County,
California:  ACF 59-372.  (California, Dept. of Food and Agriculture,
Agricultural Chemicals and Feed; unpublished study; CDL:248429-E)

00117088 Maddy, K.; Edmiston, S.; Kahn, C.; et al. (1977) A Study of the
Decay of Captan on the Foliage and Fruit of Strawberries in Santa Cruz
County, California: ACF 59-376.  (California, Dept. of Food and
Agriculture, Agricultural Chemicals and Feed; unpublished study;
CDL:248429-F)

00128355 Chevron Chemical Co. (1982) Residue Chemistry Data: [Captan]. 
(Compilation; unpublished study received May 19, 1983 under 3F2898;
CDL:071624-A; 071625; 071626)

00159596 Captan Task Force (1985) Summary of Residue Data:  Orthocide
50W in Almonds: Test No. T-6268.  Unpublished compilation prepared in
cooperation with Morse Labs.  6 p.

00159597 Captan Task Force (1985) Summary of Residue Data:  Orthocide
50W in Red Delicious Apples: Test No. T-6649.  Unpublished compilation
prepared in cooperation with Morse Labs.  18 p.

00159599 Captan Task Force (1985) Summary of Residue Data:  Orthocide
50WP in Celery: Test No. T-6269.  Unpublished compilation prepared in
cooperation with Morse Labs.  35 p.

00159601 Captan Task Force (1985)  Orthocide 50W Residues in Grapes. 
Unpublished compilation prepared in cooperation with Morse Labs.  29 p.

00159605 Captan Task Force (1985) Summary of Residue Data:  Orthocide
50W in Leaf Lettuce: Test Nos. T-6276 and T-6285.  Unpublished
compilation prepared in cooperation with Morse Labs.  20 p.

00159606 Captan Task Force (1986) Summary of Residue Data:  Orthocide
50W in Spinach: Test No. T-6280.  Unpublished compilation prepared in
cooperation with Morse Labs.  12 p.

00159607 Captan Task Force (1985) Summary of Residue Data:  Orthocide
50W in Strawberries.  Unpublished compilation prepared in cooperation
with Morse Labs.  20 p.

00162037 Breault, G. (1986) Addendum to Residue Reduction of Captan and
THPI on Crops: Data Call in: R-218.  Unpublished compilation prepared by
Chevron Chemical Co.  110 p.

40010501 Graham, D. (1986) Captan--Magnitude of the Residues: Poultry
and Eggs (Magnitude of Residues of Captan and its Major Metabolites in
Eggs and Chicken Tissues): Project ID. RRC 86-63.  Unpublished study
prepared by Stauffer Chemical Co.  183 p.

40189802 Reed D. Smith Associates, Inc. (1987) Captan: Magnitude of
Residue:  Crop Field Trials: Almond:  Chevron Study No. 056131-B. 
Unpublished study prepared in cooperation with Morse Laboratories.  246
p.

40189803 Reed D. Smith Associates, Inc. (1987) Captan: Magnitude of
Residue:  Crop Field Trials: Apples:  Chevron Study No. 056131-C. 
Unpublished study prepared in cooperation with Morse Laboratories.  454
p.

40189804 Reed D. Smith Associates, Inc. (1987) Captan: Magnitude of
Residue:  Processed Food/Feed Study: Apples: Chevron Study No. 056131-D.
 Unpublished study prepared in cooperation with Morse Laboratories.  82
p.

40189805 Reed D. Smith Associates, Inc. (1987) Captan: Magnitude of
Residue: Crop Field Trials: Apricot: Chevron Study No. 056131-E. 
Unpublished study prepared in cooperation with Morse Laboratories.  163
p.

40189806 Reed D. Smith Associates, Inc. (1987) Captan: Magnitude of
Residue: Crop Field Trials: Beet: Chevron Study No. 056131-F. 
Unpublished study prepared in cooperation with Morse Laboratories.  97
p.

40189808 Reed D. Smith Associates, Inc. (1987) Captan: Magnitude of
Residue: Crop Field Trials: Cherry: Chevron Study No. 056131-H.  210 p.

40189809 Reed D. Smith Associates, Inc. (1987) Captan: Magnitude of
Residue: Crop Field Trials: Corn: Chevron Study No. 056131-I. 
Unpublished study prepared in cooperation with Morse Laboratories.  187
p.

40189811 Reed D. Smith Associates, Inc. (1987) Captan: Magnitude of
Residue:  Crop Field Trials: Grape: Chevron Study No. 056131-K.  378 p.

40189812 Reed D. Smith Associates, Inc. (1987) Captan: Magnitude of
Residue: Processed Food/Feed Study: Grapes: Chevron Study 045131-L. 
Unpublished study prepared in cooperation with Morse Laboratories.  154
p.

40189813 Reed D. Smith Associates, Inc. (1987) Captan: Magnitude of
Residue: Crop Field Trials: Nectarine: Chevron Study No. 056131-M.  151
p.

40189814 Reed D. Smith Associates, Inc. (1987) Captan: Magnitude of
Residue: Crop Field Trials: Peach: Chevron Study No. 056131-N.  339 p.

40189815 Reed D. Smith Associates, Inc. (1987) Magnitude of Residue:
Crop Field Trials: Pear: Chevron Study No. 056131-O.  Unpublished study
prepared in cooperation with Morse Laboratories.  316 p.

40189816 Reed D. Smith Associates, Inc. (1987) Captan: Magnitude of
Residue:  Crop Field Trials: Plum: Chevron Study No. 056131-P. 
Unpublished study prepared in cooperation with Morse Laboratories.   217
p.

40189817 Reed D. Smith Associates, Inc. (1987) Captan: Magnitude of
Residue: Processed Food/Feed Study: Prunes: Chevron Study No. 056131-Q. 
Unpublished study prepared in cooperation with Morse Laboratories.  77
p.

40189820 Reed D. Smith Associates, Inc. (1987) Captan: Magnitude of
Residue: Crop Field Trials: Soybean: Chevron Study No. 056131-T. 
Unpublished study prepared in cooperation with Morse Laboratories.  174
p.

40189821 Reed D. Smith Associates, Inc. (1987) Captan: Magnitude of
Residue: Crop Field Trials: Spinach: Chevron Study No. 056131-U. 
Unpublished study prepared in cooperation with Morse Laboratories.   121
p.

40189822 Reed D. Smith Associates, Inc. (1987) Captan: Magnitude of
Residue: Crop Field Trials: Strawberries: Chevron Study No. 056131-V. 
Unpublished study prepared in cooperation with Morse Laboratories.  262
p.

40189823 Reed D. Smith Associates, Inc. (1987) Captan: Magnitude of
Residue: Crop Field Trials: Tomato: Chevron Study No. 056131-W. 
Unpublished study prepared in cooperation with Morse Laboratories.  217
p.

40189824 Reed D. Smith Associates, Inc. (1987) Captan: Magnitude of
Residue: Processed Food/Feed Study: Tomatoes: Chevron Study No.
056131-X.  Unpublished study prepared in cooperation with Morse
Laboratories.  123 p.

40658002 Daun, R. (1988) [Trichloromethyl-[Carbon 14]]Captan:  Nature of
the Residue in Livestock-Lactating Goats: Laboratory Project ID: HLA
6183-105.  Unpublished study prepared by Hazleton Laboratories, Inc.  67
p. 

40658003 Daun, R. (1988) [Trichloromethyl-[Carbon 14]]Captan:  Nature of
the Residue in Livestock-Laying Hens: Laboratory Project ID: HLA
6183-106.  Unpublished study prepared by Hazleton Laboratories America,
Inc.  62 p. 

40658004 Daun, R. (1988) [Cyclohexene-1,2-[Carbon 14]]Captan:  Nature of
the Residue in Livestock-Laying Hens: Laboratory Project ID: HLA
6183-104.  Unpublished study prepared by Hazleton Laboratories America,
Inc.  79 p.

40658005 Chen, Y. (1988) Plant Metabolism Study of
[Trichloromethyl-[Carbon 14]-Captan:  Laboratory Project ID: 
MEF-0009/8808900.  Unpublished study prepared by Chevron Chemical Co. 
37 p.

40658006 Chen, Y. (1988) Plant Metabolism Study of
[Cyclohexene-1,2-[Carbon 14]]-Captan:  Laboratory Project ID:
MEF-0010/8805420.  Unpublished study prepared by Chevron Chemical Co. 
38 p.

40745402 Reed D. Smith Associates, Inc. (1988) Captan ... Magnitude of
Residue, Crop Field Trials: Almond: Project ID. 87-718.  Unpublished
compilation prepared in cooperation with Morse Laboratories.   125 p.

40745403 Reed D. Smith Associates, Inc. (1988) Captan ... Magnitude of
Residue, Crop Field Trials: Apple: Project ID. 87-304.  Unpublished
compilation prepared in cooperation with Morse Laboratories.  86 p.

40745405 Reed D. Smith Associates, Inc. (1988) Captan ... Magnitude of
Residue, Crop Field Trials: Grape: Project ID. 87-167.  Unpublished
compilation prepared in cooperation with Morse Laboratories.  88 p.

40745406 Reed D. Smith Associates, Inc. (1988) Captan ... Magnitude of
Residue, Crop Field Trials: Peach: Project ID. 87-984.  Unpublished
compilation prepared in cooperation with Morse Laboratories.  110 p.

40745407 Reed D. Smith Associates, Inc. (1988) Captan ... Magnitude of
Residue, Crop Field Trials: Peach (WA): Project ID. 87-916.  89 p.

40745408 Reed D. Smith Associates, Inc. (1988) Captan ... Magnitude of
Residue, Crop Field Trials: Strawberry: Project ID. 87-722.  Unpublished
compilation prepared in cooperation with Morse Laboratories.  107 p.

40752301 McKay, J. (1988) Captan and THPI--Storage Stability Study:
Various Crops: Interim Report: Laboratory Project ID RRC-88-35. 
Unpublished study prepared by Chevron Environmental Center in
cooperation with Morse Laboratories, Inc. and Hazleton Laboratories
America, Inc.  247 p.

41039101 Biehn, W. (1989) Captan: Magnitude of Residue on Blueberry:
IR-4 PR No. 3458.  Unpublished study prepared by Morse Laboratories,
Inc.  237 p.

41149101 Curry, K. (1989) Captan Magnitude of the Residue Study in
Soybeans Grown from CAPTAN-treated Seed: Project ID WRC 89-31. 
Unpublished study prepared by Morse Laboratories, Inc.  125 p.

41149102 Curry, K. (1989) Captan Magnitudes of the Residue Study in
Spinach Grown from CAPTAN-treated Seed: Project ID WRC 89-32. 
Unpublished study prepared by Morse Laboratories, Inc.  152 p.

41149103 Curry, K. (1989) Captan Magnitude of the Residue Study in Corn
Grown from CAPTAN-treated Seed: Project ID WRC 89-33.  Unpublished study
prepared by Morse Laboratories, Inc.  144 p.

41149104 Curry, K. (1989) Captan Magnitudes of the Residue Study in
Beets Grown from CAPTAN-treated Seed: Project ID WRC 89-34.  Unpublished
study prepared by Morse Laboratories, Inc.  141 p.

41306101 Curry, K. (1989) Captan: Magnitude of the Residue Study on
Winter Wheat Grown from Captan-Treated Seed:  Lab Project Number: 
RR/89/053B.   Unpublished study prepared by  Morse Laboratories, Inc. 
188 p. 

41306102 Curry, K. (1989) Captan: Magnitude of the Residue Study on
Soybean Forage Grown from Captan-Treated Seed:  Lab Project Number: 
RR/89/062B.   Unpublished study prepared by Morse Laboratories, Inc. 
104 p.

41386501 Davy, G. (1989) ICI Agrochemicals Residue Analytical Method No.
166: The Determination of Residues of Tetrahydrophthalimide, 3-Hydroxy
Tetrahydrophthalimide and 5-Hydroxy Tetrahydrophthalimide in Milk and
Animal Tissues: A Gas Liquid Chromatographic:  Mass-selective Detector
Method Using External Standardization.  Unpublished study prepared by
ICI Agrochemicals.  38 p.

41393001 Yancey, M. (1989) Final Report on PR 88-5 Analytical Validation
for ICI Agrochemical Residue Analytical Method 152 for Residues of THPI,
3-Hydroxy THPI and 5-Hydroxy THPI in Eggs: Lab Project Number:
NO967-0701: ICI Protocol NO. CAPT-CL-AM-01.  Unpublished study prepared
by Battelle.  27 p.

41404001 Ewing, A.; Krauter, G.; Ruzo, L. (1990) Confined Rotational
Crop Study of [Ring-carbon 14] and [Trichloromethyl-carbon 14]-Captan
with Beets Lettuce and Wheat:  Lab Project Number:  PTRL-EAST 241: 
PTRL-WEST 137W.  Unpublished study prepared by Pharmacology & Toxicology
Research Laboratory-West.  124 p.

41406901 Davy, G.; Atreya, N. (1989) The Determination of Residues of
Tetrahydrophthalimide, 3-Hydroxy Tetrahydrophthalimide and 5-Hydroxy
Tetrahydrophthalimide in Eggs:  A Gas Liquid Chromatographic
Mass-selective Detector Method Using External Standardization. 
...Method No. 152.  Unpublished study prepared by ICI Agrochemicals,
Jealotts Hill Research Station.  30 p.

41468401 Curry, K. (1990) Residue Data Review for Soybean and Wheat Seed
Treatments with Captan, Record No. 256461; ID No. 10182-293; DEB No.
6142; MRID Nos. 413061-01 and-02 and Residue Data Review for Corn,
Soybeans, Beet and Spinach Seed Treatments with Captan, DEB No. 5589,
EPA No. 239-124; MRID Nos. 411491-01 through-04.  Unpublished study
prepared by Captan Task Force, 30 p.

41557601 McKay, J. (1990) Captan and THPI--Storage Stability Study: 
Various Crops.  Storage Stability Validation for Captan
(N(trichloromethylthio) cyclohex-4-ene-1,2-dicarboximide and THPI
(tetrahydrophtalimide) in Raw and Processed Agricultural Commodities: 
Lab Project Number:  RR90-368B.  Unpublished study prepared by Chevron
Environmental Ctr. in coop. with Morse Labs, Inc. and Hazleton Labs
America, Inc.  354 p.

41746001 Chen, Y. (1988) Plant Metabolism Study of
(trichloromethyl-[carbon14]

Cyclohexene-1,2-[carbon 14])-Captan:  Lab Project Number: 
MEF-0010/8805420:  MEF-0009/8808900.  Unpublished study prepared by
Chevron Chemical Co.  41 p.

42109601 Yeh, S. (1988) Addendum to Carbon-14 Captan Plant Metabolism
Studies:  Lab Project Number:  MEF-009:  MEF-010:  RR 91-091B. 
Unpublished study prepared by Chevron Chemical Co.  20 p.

42252201 McKay, J. (1990) Captan 50-WP: Magnitude-of-the-Residue Study
on Apples Residue Data for Captan and Tetrahydrophthalimide:  Lab
Project Number: CAPT-89-MR-02.  Unpublished study prepared by ICI
Americas Inc., and Morse Labs., Inc.  145 p.

42252202 McKay, J. (1991) Captan 50-WP: Magnitude-of-the-Residue Study
on Apples Treated with a Post Harvest Dip: Lab Project Number:
CAPT-90-MR-03.  Unpublished study prepared by ICI Americas Inc., and
Morse Labs., Inc.  91 p.

42254202 McKay, J. (1990) Captan 50-WP: Magnitude-of-the-Residue Study
on Grapes: Residue Data for Captan and Tetrahydrophthalimide: Lab
Project Number: CAPT-89-MR-07: RR 90-379B.  Unpublished study prepared
by ICI Americas, Inc. and Morse Laboratories, Inc.  176 p.

42296002 Wiebe, L. (1991) Captan: Magnitude of the Residue of Captan
Metabolites in Bovine Meat and Milk: Lab Project Number: CAPT-90-AT-01. 
Unpublished study prepared by ICI Americas, Inc.  364 p.

42296003 Riggle, B. (1991) Captan 50-WP:
Magnitude-of-thⵥ敒楳畤⁥瑓摵⁹湯倠潲散獳摥䄠灰敬倠潲
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ᜀ42296004 Riggle, B. (1991) Captan 50-WP: Magnitude-of-the-Residue
Study on Processed Grape Products: Lab Project Number: CAPT-89-PR-02. 
Unpublished study prepared by ICI Americas, Inc.  227 p.

42378401 Yeh, S. (1992) Addendum to [carbon 14]-Captan Confined
Rotational Crop Study (Reference: MRID 41404001; EFGWB #90-0738): Lab
Project Number: 241: 137W: RR 92-055B.  Unpublished study prepared by
PTRL-EAST and PTRL-WEST.  25 p.

42563101 Iwata, Y. (1992) Captan: Magnitude of the Residue Study on
Processed Grape Products: Lab Project Number: CAPT-90-PR-02. 
Unpublished study prepared by ICI Americas Inc.  140 p.

42563102 Iwata, Y. (1992) Captan: Magnitude of the Residue Study on
Processed Apple Products: Lab Project Number: CAPT-90-023B.  Unpublished
study prepared by ICI Americas Inc.  336 p.

42568801 Mueller, A. (1992) Interim Report for Nature of the Residue in
Livestock-Replacement Study for MRIDs 40658002-40658004 in Response to
DEB#s 6525 and 6526.  Unpublished study prepared by ICI Americas, Inc. 
40 p.

42712801 Biehn, W. (1992) Captan: Magnitude of Residue on
Raspberries-1991 and 1992 Trials: Lab Project Number: 3953.  Unpublished
study prepared by IR-4 Satellite Lab, North Dakota State Univ.  234 p.

42756401 Renwick, R.; Skidmore, M. (1993) Captan: Metabolism in Hens
Following Dosing at 10 micro-g/g in the Diet: Lab Project Number:
91JH312: RJ1345B.  Unpublished study prepared by ICI Agrochemicals.  156
p.

42803901 Rhodes, M. (1993) An Addendum to MRIDs 40752301, 41557601, and
40189801: A Summary of Storage Stability Information for Captan in
Magnitude of the Residue and Processing Studies for Foliar and
Post-Harvest Uses as was Requested in the Residue Chemistry
Reregistration Standard Update.  Unpublished study prepared by Reed D.
Smith Assocs., Morse Labs, Hazleton Labs America, Inc. and Chevron Env.
Ctr.  36 p.

43266701 Mathis, S & Skidmore, M. (1994) 14C-Trchloromethyl Captan:
Metabolism in Hens Following Dosing at 10 mg/kg in the Diet:Nature of
the Residue in Eggs and Tissue, Final Report.  Lab Project Number:
91JH366: RJ1639B.  Unpublished study prepared by ICI Agrochemicals.  158
p.

43266702 Powell, S., Miles, P. & Skidmore, M. (1994) 14C-Trchloromethyl
Captan: Metabolism in Goats Following Dosing at 50 mg/kg in the
Diet:Nature of the Residue in Milk and Tissue, Final Report.  Lab
Project Number: 91JH955: RJ1650B.  Unpublished study prepared by ICI
Agrochemicals.  185 p.

43489701 Biehn, W. (1994) Captan: Magnitude of Residue on Strawberries.
Laboratory Project No. IR-4 PR No. 5326. Unpublished study prepared by
IR-4 Satellite Lab, Rutgers University. 606 p.

43875603 Meyers, T. & Wiebe, L. (1995) Captan : Stabilities of Captan in
Milk and Five Captan Metabolites in Animal Tissues and Milk During
Storage at -20∘ C ± 10∘  C. Lab Report No. RR95-021B. Study No.
CAPT-90-55-01. Unpublished study prepared by Morse Laboratories,
Sacramento, CA. 56 p.

44227201 Biehn, W. (1997) Captan: Magnitude of Residue on Raspberries -
1995 Trials. Laboratory Project No. IR-4 PR No. 3953. Unpublished study
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