Document ID: EPA-HQ-OPP-2006-0292-0005
Agency: epa
Document Type: Supporting & Related Material
Title: 
Posted Date: 2006-08-30T04:00Z

S­
metolachlor
Dietary
Exposure
Assessment
DP
Num:
329632
PC
Code:
108800
Page:
1
of
21
UNITED
STATES
ENVIRONMENTAL
PROTECTION
AGENCY
WASHINGTON,
D.
C.
20460
OFFICE
OF
PREVENTION,
PESTICIDES
AND
TOXIC
SUBSTANCES
MEMORANDUM
Date:
6/
28/
06
Subject:
S­
Metolachlor
Acute
and
Chronic
Dietary
Exposure
Assessments
for
the
Section
18
Registrations
on
Cilantro,
Collards,
Kale,
Mustard
Greens;
and
Section
3
Registration
on
Pumpkins
and
Tolerance
without
Registration
on
Winter
Squash.

PC
Code:
108800
and
108801
Decision
Number:
365612
DP
Number:
329632
ID
Num:
06OH05
&
5E7015
Reviewer:
W.
Cutchin,
Chemist
ARIA
Team/
Technical
Review
Branch
Registration
Division
(
7505P)

Through:
T.
Bloem,
Chemist
L.
Cheng,
Chemist
Dietary
Exposure
Science
Advisory
Council
(
DESAC)
HED
(
7509P)

To:
W.
Cutchin,
Chemist
ARIA
Team/
Technical
Review
Branch
Registration
Division
(
7505P)

Executive
Summary
Acute
and
chronic
dietary
risk
assessments
were
conducted
using
the
Dietary
Exposure
Evaluation
Model
(
DEEM­
FCID
 
,
Version
2.03)
which
uses
food
consumption
data
from
the
USDA's
Continuing
Surveys
of
Food
Intakes
by
Individuals
(
CSFII)
from
1994­
1996
and
1998.
The
analyses
were
performed
to
support
Section
18
requests
for
the
use
of
S­
metolachlor
on
S­
metolachlor
Dietary
Exposure
Assessment
DP
Num:
329632
PC
Code:
108800
Page:
2
of
21
cilantro,
collards,
kale,
mustard
greens;
and
Section
3
registration
on
pumpkins
and
tolerance
without
registration
on
winter
squash.

Both
the
acute
and
chronic
analyses
assume
tolerance­
level
residues
on
all
crops
with
established,
pending,
or
proposed
tolerances
for
metolachlor
and/
or
S­
metolachlor
(
collectively
referred
to
as
S­
metolachlor
in
this
document).
In
cases
where
separate
tolerance
listings
occur
for
both
metolachlor
and
S­
metolachlor
on
the
same
commodity,
the
higher
value
of
the
two
is
used
in
the
analyses.

Acute
Dietary
Exposure
Results
and
Characterization
An
acute
dietary
analysis
for
S­
metolachlor
was
conducted
using
tolerance
levels
and
100
%
CT
for
all
existing
and
proposed
uses.
The
highest
drinking
water
estimate
for
acute
exposure,
322
ppb,
was
used
in
the
analysis.
The
dietary
exposure
estimate
to
the
U.
S.
population
was
<
1%
aPAD
and
the
most
highly
exposed
subgroup,
all
infants
<
1
yr
old,
at
2%
aPAD.
The
results
of
the
analysis
indicate
that
acute
risk
from
the
dietary
exposure
to
S­
metolachlor
from
the
existing
and
requested
uses
did
not
exceed
HED's
level
of
concern
for
U.
S.
population
or
any
population
subgroup.

Chronic
Dietary
Exposure
Results
and
Characterization
A
chronic
dietary
analysis
for
S­
metolachlor
was
conducted
using
tolerance
levels
and
100
%
CT
data
for
all
existing
and
proposed
uses.
The
highest
drinking
water
estimate
for
chronic
exposure,
103
ppb,
was
used
in
the
analysis.
The
dietary
exposure
estimate
to
the
U.
S.
population
was
4%
cPAD
and
the
most
highly
exposed
subgroup,
all
infants
<
1
yrs
old,
at
10%
cPAD.
The
results
of
the
analysis
indicate
that
chronic
risk
from
the
dietary
exposure
to
S­
metolachlor
from
the
existing
and
requested
uses
did
not
exceed
HED's
level
of
concern
for
the
U.
S.
population
or
any
population
subgroup.

Cancer
Dietary
Exposure
Results
and
Characterization
The
HED's
Cancer
Assessment
Review
Committee
(
CARC)
evaluated
the
carcinogenic
potential
of
metolachlor
as
a
Group
C
carcinogen,
possible
human
carcinogen
based
on
liver
tumors
in
rats
with
risk
quantitated
using
a
non­
linear
approach,
therefore,
a
separate
quantification
of
human
cancer
risk
is
not
required.

I.
Introduction
Dietary
risk
assessment
incorporates
both
exposure
and
toxicity
of
a
given
pesticide.
For
acute
and
chronic
assessments,
the
risk
is
expressed
as
a
percentage
of
a
maximum
acceptable
dose
(
i.
e.,
the
dose
which
HED
has
concluded
will
result
in
no
unreasonable
adverse
health
effects).
This
dose
is
referred
to
as
the
Population­
adjusted
Dose
(
PAD).
The
PAD
is
equivalent
to
the
reference
dose
(
RfD)
divided
by
the
special
Food
Quality
Protection
Act
(
FQPA)
Safety
S­
metolachlor
Dietary
Exposure
Assessment
DP
Num:
329632
PC
Code:
108800
Page:
3
of
21
Factor.

For
acute
and
non­
cancer
chronic
assessments,
HED
is
concerned
when
the
estimated
dietary
risk
exceeds
100%
of
the
PAD.
For
cancer
assessments
(
not
applicable
to
metolachlor),
HED
is
generally
concerned
when
the
estimated
risk
exceeds
one
in
one
million
(
i.
e.,
the
risk
exceeds
1
x
10­
6).
References
which
discuss
the
acute
and
chronic
risk
assessments
in
more
detail
are
available
on
the
EPA/
pesticides
web
site:
"
Available
Information
on
Assessing
Exposure
from
Pesticides,
A
User's
Guide,"
6/
21/
2000,
web
link:
http://
www.
epa.
gov/
fedrgstr/
EPA­
PEST/
2000/
July/
Day­
12/
6061.
pdf;
or
see
SOP
99.6
(
8/
20/
99).

The
most
recent
dietary
risk
assessment
for
metolachlor
was
conducted
by
M.
Doherty
(
9/
16/
04,
DP
Num:
306830)
using
the
Lifeline
 
Model
Version
2.0.

II.
Residue
Information
These
analyses
are
based
on
tolerance­
level
residues
listed
in
40
CFR
180.368
as
of
August
11,
2004
for
existing
uses
and
HED­
recommended
tolerance
levels
for
the
subject­
listed
new
uses
(
Table
1).
Residues
of
concern
include
S­
metolachlor
and
its
metabolites,
determined
as
the
derivatives
CGA­
37913
and
CGA­
49751.
For
processed
commodities,
default
processing
factors
from
DEEM
version
7.76
that
are
greater
than
or
equal
to
1.5
were
used
in
the
analysis.

Table
1.
Proposed
Tolerances.
Commodity
Proposed
Tolerance
(
ppm)
cilantro
1
collards
1
cale
1
custard
greens
1
pumpkins
0.1
winter
squash
0.1
III
Program
and
Consumption
Information
IIIa.
DEEM­
FCID
 
Program
and
Consumption
Information
S­
metolachlor
acute
and
chronic
dietary
exposure
assessments
were
conducted
using
the
Dietary
Exposure
Evaluation
Model
software
with
the
Food
Commodity
Intake
Database
(
DEEM­
FCID
 
,
Version
2.03),
which
incorporates
consumption
data
from
USDA's
Continuing
Surveys
of
Food
Intakes
by
Individuals
(
CSFII),
1994­
1996
and
1998.
The
1994­
96,
98
data
are
based
on
the
reported
consumption
of
more
than
20,000
individuals
over
two
non­
consecutive
survey
days.
Foods
"
as
consumed"
(
e.
g.,
apple
pie)
are
linked
to
EPA­
defined
food
commodities
(
e.
g.
apples,
peeled
fruit
­
cooked;
fresh
or
N/
S;
baked;
or
wheat
flour
­
cooked;
fresh
or
N/
S,
baked)
using
publicly
available
recipe
translation
files
developed
jointly
by
USDA/
ARS
and
S­
metolachlor
Dietary
Exposure
Assessment
DP
Num:
329632
PC
Code:
108800
Page:
4
of
21
EPA.
For
chronic
exposure
assessment,
consumption
data
are
averaged
for
the
entire
U.
S.
population
and
within
population
subgroups,
but
for
acute
exposure
assessment
are
retained
as
individual
consumption
events.
Based
on
analysis
of
the
1994­
96,
98
CSFII
consumption
data,
which
took
into
account
dietary
patterns
and
survey
respondents,
HED
concluded
that
it
is
most
appropriate
to
report
risk
for
the
following
population
subgroups:
the
general
U.
S.
population,
all
infants
(<
1
year
old),
children
1­
2,
children
3­
5,
children
6­
12,
youth
13­
19,
adults
20­
49,
females
13­
49,
and
adults
50+
years
old.

For
chronic
dietary
exposure
assessment,
an
estimate
of
the
residue
level
in
each
food
or
food­
form
(
e.
g.,
orange
or
orange
juice)
on
the
food
commodity
residue
list
is
multiplied
by
the
average
daily
consumption
estimate
for
that
food/
food
form
to
produce
a
residue
intake
estimate.
The
resulting
residue
intake
estimate
for
each
food/
food
form
is
summed
with
the
residue
intake
estimates
for
all
other
food/
food
forms
on
the
commodity
residue
list
to
arrive
at
the
total
average
estimated
exposure.
Exposure
is
expressed
in
mg/
kg
body
weight/
day
and
as
a
percent
of
the
cPAD.
This
procedure
is
performed
for
each
population
subgroup.

For
acute
exposure
assessments,
individual
one­
day
food
consumption
data
are
used
on
an
individual­
by­
individual
basis.
The
reported
consumption
amounts
of
each
food
item
can
be
multiplied
by
a
residue
point
estimate
and
summed
to
obtain
a
total
daily
pesticide
exposure
for
a
deterministic
exposure
assessment,
or
"
matched"
in
multiple
random
pairings
with
residue
values
and
then
summed
in
a
probabilistic
assessment.
The
resulting
distribution
of
exposures
is
expressed
as
a
percentage
of
the
aPAD
on
both
a
user
(
i.
e.,
only
those
who
reported
eating
relevant
commodities/
food
forms)
and
a
per­
capita
(
i.
e.,
those
who
reported
eating
the
relevant
commodities
as
well
as
those
who
did
not)
basis.
In
accordance
with
HED
policy,
per
capita
exposure
and
risk
are
reported
for
all
tiers
of
analysis.
However,
for
tiers
1
and
2,
any
significant
differences
in
user
vs.
per
capita
exposure
and
risk
are
specifically
identified
and
noted
in
the
risk
assessment.

IV.
Toxicological
Information
Metolachlor
(
CGA
24705),
which
consists
of
50%
each
of
the
R­
enantiomer
(
CGA
77101)
and
the
S­
enantiomer
(
CGA
77102,
also
referred
to
as
alpha
metolachlor),
was
first
registered
in
1976.
The
registrant
(
originally
CIBA­
GEIGY,
now
Syngenta)
developed
a
process
to
produce
a
higher
ratio
of
CGA
77102:
CGA
77101(
88:
12)
and
applied
for
reduced
risk
status
based
on
decreased
application
rates
in
1996.
To
support
the
registration
of
S­
metolachlor,
bridging
toxicology
data
were
submitted.
The
HED
Reference
Dose
Peer
Review
Committee
met
on
April
10,
1997
to
determine:
1)
whether
the
limited
toxicological
data
were
adequate
to
demonstrate
that
both
s­
metolachlor
and
metolachlor
have
identical
properties;
2)
if
so,
the
applicability
of
the
data
base
for
metolachlor
in
the
safety
evaluation
of
S­
metolachlor;
and
3)
if
a
separate
reference
dose
(
RfD)
was
required.
The
Committee
concluded
that,
without
metabolism
studies
and
side­
by­
side
subchronic
studies
conducted
in
the
same
strain
of
rat
using
comparable
dose
levels
of
test
materials,
the
identification
of
any
qualitative
or
quantitative
differences
in
the
toxicological
properties
of
S­
metolachlor
and
the
racemic
mixture
S­
metolachlor
Dietary
Exposure
Assessment
DP
Num:
329632
PC
Code:
108800
Page:
5
of
21
(
metolachlor)
was
not
possible.

The
studies
required
by
the
1997
RfD
Committee,
along
with
a
series
of
acute,
subchronic,
developmental
and
mutagenicity
studies
on
two
water
metabolites,
CGA
354743
and
CGA
51202,
were
submitted
and
reviewed.
On
August
14,
2001,
the
HED
Metabolism
Assessment
Review
Committee
(
MARC)
considered
two
issues
regarding
the
toxicity
and
metabolism
of
metolachlor,
S­
metolachlor,
and
the
metabolites
CGA
354743
and
CGA
51202.
The
MARC
concluded
that
the
available
studies
are
not
adequate
to
make
a
determination
of
comparable
metabolism
and
given
the
lack
of
certain
data,
such
as
proposed
metabolic
pathway
for
Smetolachlor
and
identification
of
metabolites
for
both
chemicals,
and
uncertainties
about
findings
in
some
studies,
such
as
quantitative
differences
in
metabolites,
it
was
not
possible
to
determine
if
the
metabolism
of
the
racemic
mixture
and
S­
metolachlor
are
comparable.
However,
the
Committee
questioned
how
much
this
information
contributed
to
assessing
the
relative
toxicity
of
metaloachlor
and
S­
metolachlor.
Additional
metabolism
studies
were
not
recommended
and
the
MARC
believed
that
S­
metolachlor
appears
to
have
either
comparable
or
decreased
toxicity
in
comparison
to
the
racemic
mixture.
The
MARC
also
concluded
that
the
metabolites
CGA
354743
and
CGA
51202
appear
to
be
less
toxic
than
the
parents
metolachlor
and
S­
metolachlor;
however,
the
MARC
concluded
that
CGA
354743
and
CGA
51202
should
be
included
in
the
water
risk
assessment
since
they
were
found
in
greater
abundance
than
the
parent(
s)
in
water
monitoring
studies.

On
September
6,
2001,
the
Health
Effects
Division
(
HED)
Hazard
Identification
Assessment
Review
Committee
(
HIARC)
reviewed
the
toxicology
databases
for
metolachlor
and
S­
metolachlor
with
regard
to
the
acute
and
chronic
Reference
Doses
(
RfDs)
and
the
toxicological
endpoint
selection
for
use
as
appropriate
in
dietary
exposure
risk
assessments.
Prior
evaluations
done
by
the
HED
RfD
Peer
Review
Committee,
the
Toxicology
Endpoint
Selection
committee
and
the
HIARC
were
on
August
25,
1993,
March
14,
1994,
January
1,
1995,
October
28,
1997
(
metolachlor)
and
July
17,
1997
(
S­
metolachlor).
The
HIARC
concluded
that
S­
metolachlor
and
metolachlor
have
comparable
toxicity
profiles.
Studies
with
both
chemicals
were
used
interchangeably
for
toxicology
endpoint
selection
(
HED
DOC.
NO.
014691).
The
potential
for
increased
susceptibility
of
infants
and
children
from
exposure
to
metolachlor
and
S­
metolachlor
was
also
evaluated
as
required
by
the
Food
Quality
Protection
Act
(
FQPA)
of
1996.

On
November
5,
2001,
the
FQPA
Safety
Factor
Committee
evaluated
the
available
hazard
and
exposure
data
for
metolachlor
and
S­
metolachlor
and
made
the
recommendation
for
the
FQPA
safety
factor
to
be
used
in
the
human
health
risk
assessments.
The
Committee
concluded
that
the
FQPA
safety
factor
could
be
removed
(
1X)
in
assessing
the
potential
risks
posed
by
these
chemicals
(
C.
Christensen
memo,
11/
14/
01).

Table
2.
Summary
of
Toxicological
Dose
and
Endpoints
for
Metolachlor
and
S­
metolachlor
for
Use
in
Dietary
Exposure
Assessment.

Exposure
Scenario
Dose
(
mg/
kg/
day)
Endpoint
Study
S­
metolachlor
Dietary
Exposure
Assessment
DP
Num:
329632
PC
Code:
108800
Page:
6
of
21
NOAEL=
300
UF
=
100
FQPA
=
1X
death,
clinical
signs
of
toxicity
(
clonic
and/
or
tonic
convulsions,
excessive
salivation,
urine­
stained
abdominal
fur
and/
or
excessive
salivation)
and
decreased
body
weight
gain
prenatal
developmental
toxicity
study
in
rats
with
metolachlor
Acute
Dietary
Acute
RfD
=
3.0
mg/
kg
NOAEL
=
9.7
UF
=
100
FQPA
=
1X
decreased
body
weight
gain
in
females
chronic
study
in
dogs
with
metolachlor
Chronic
Dietary
Chronic
RfD
=
0.1
mg/
kg/
day
At
the
4th
HED
Carcinogenicity
Peer
Review
Committee
(
CPRC)
meeting
on
July
27,
1994,
metolachlor
was
classified
as
a
Group
C
carcinogen,
possible
human
carcinogen
based
on
liver
tumors
in
rats
with
risk
quantitated
using
a
non­
linear
approach.
The
chronic
dietary
exposure
assessment
based
on
effects
observed
in
the
chronic
dog
study
is
sufficiently
protective
of
cancer
effects
and
a
separate
cancer
analysis
is
not
required.

V.
Results/
Discussion
As
stated
above,
for
acute
and
chronic
dietary
assessments,
HED
is
concerned
when
dietary
risk
exceeds
100%
of
the
PAD.
The
DEEM­
FCID
 
analyses
estimate
the
dietary
exposure
of
the
U.
S.
population
and
various
population
subgroups.
The
exposure
results
reported
in
Tables
3
and
4
are
for
the
general
U.
S.
Population,
all
infants
(<
1
year
old),
children
1­
2,
children
3­
5,
children
6­
12,
youth
13­
19,
females
13­
49,
adults
20­
49,
and
adults
50+
years.
The
acute
exposure
results
reported
in
Table
3
include
at
the
95th
percentile
general
US
population
at
<
1%
aPAD
and
the
most
highly
exposed
subgroup,
all
infants
<
1
yrs
old,
at
2%
aPAD.
The
chronic
dietary
risk
estimates
in
Table
4
include
general
US
population
at
4%
cPAD
and
the
most
highly
exposed
subgroup,
children
1­
2
yrs
old,
at
10%
cPAD.
All
the
dietary
risk
estimates
are
below
100%
of
the
PADs.
A
determination
of
cancer
dietary
risk
was
not
required.

The
acute
and
chronic
analyses
are
highly
conservative,
Tier
1
dietary
exposure
assessments
using
100%
CT
and
tolerance
level
residues
for
all
commodities.
Further
refinement
to
the
analyses
could
be
made
through
the
use
of
anticipated
residues,
incorporation
of
additional
percentages
of
crops
treated
with
S­
metolachlor,
and/
or
monitoring
data
that
better
reflect
residues
at
the
time
of
consumption.
Since
risk
estimates
are
well
below
HED's
level
of
concern,
a
more
highly
refined
analysis
is
not
needed
at
this
time.

Table
3.
Results
of
Acute
Dietary
Exposure
Analysis
Population
Subgroup
aPAD
(
mg/
kg/
day)
95th
Percentile
99th
Percentile
99.9th
Percentile
S­
metolachlor
Dietary
Exposure
Assessment
DP
Num:
329632
PC
Code:
108800
Page:
7
of
21
Exposure
(
mg/
kg/
day)
%
aPAD
Exposure
(
mg/
kg/
day)
%
aPAD
Exposure
(
mg/
kg/
day)
%
aPAD
General
U.
S.
Population
3.0
0.019972
<
1
0.035124
1
0.065895
2
All
Infants
(<
1
year
old)
3.0
0.066430
2
0.094323
3
0.164504
6
Children
1­
2
years
old
3.0
0.033427
1
0.050375
2
0.071410
2
Children
3­
5
years
old
3.0
0.029665
<
1
0.043437
2
0.066670
2
Children
6­
12
years
old
3.0
0.020708
<
1
0.032559
1
0.044065
2
Youth
13­
19
years
old
3.0
0.016010
<
1
0.025329
<
1
0.042886
1
Adults
20­
49
years
old
3.0
0.017578
<
1
0.028212
<
1
0.049895
2
Females
13­
49
years
old
3.0
0.017453
<
1
0.028013
<
1
0.048961
2
Adults
50+
years
old
3.0
0.015963
<
1
0.022499
<
1
0.035428
1
Table
4.
Results
of
Chronic
Dietary
Exposure
Analysis
Population
Subgroup
cPAD
(
mg/
kg/
day)
Exposure
(
mg/
kg/
day)
%
cPAD
General
U.
S.
Population
0.1
0.004113
4
All
Infants
(<
1
year
old)
0.1
0.010003
10
Children
1­
2
years
old
0.1
0.007954
8
Children
3­
5
years
old
0.1
0.007160
7
Children
6­
12
years
old
0.1
0.004914
5
Youth
13­
19
years
old
0.1
0.003352
3
Adults
20­
49
years
old
0.1
0.003613
4
Adults
50+
years
old
0.1
0.003597
4
S­
metolachlor
Dietary
Exposure
Assessment
DP
Number:
329632
PCode:
108800/
108801
Page:
8
of
21
Table
4.
Results
of
Chronic
Dietary
Exposure
Analysis
Population
Subgroup
cPAD
(
mg/
kg/
day)
Exposure
(
mg/
kg/
day)
%
cPAD
Females
13­
49
years
old
0.1
0.003521
4
VI.
Characterization
of
Inputs/
Outputs
As
noted
above,
the
residue
estimates
used
in
these
analyses
are
highly
conservative
with
respect
to
dietary
risk
assessment
and
the
outputs
from
the
dietary
model
are
likely
to
highly
overestimate
actual
dietary
exposure.
Even
with
the
unrealistically
high
exposure
estimates,
the
dietary
risk
estimates
associated
with
metolachlor
are
below
HED's
level
of
concern
for
all
population
subgroups.

VII.
Conclusions
Dietary
exposure
to
residues
of
metolachlor
and
S­
metolachlor
are
likely
to
be
low
in
comparison
to
the
toxicological
points
of
departure
used
in
human
health
risk
assessment
for
this
chemical.
Even
when
dietary
exposure
to
metolachlor
is
overestimated
based
on
conservative
assumptions
regarding
residue
values,
dietary
risk
estimates
do
not
exceed
HED's
level
of
concern
for
any
population
subgroup
under
acute
and
chronic
exposure
scenarios.

Table
5.
Summary
of
Dietary
Exposure
and
Risk
for
S­
metolachlor
Acute
Dietary
(
95th
Percentile)
Chronic
Dietary
Cancer
Population
Subgroup*
Dietary
Exposure
(
mg/
kg/
day)
%
aPAD
Dietary
Exposure
(
mg/
kg/
day)
%
cPAD
Dietary
Exposure
(
mg/
kg/
day)
Risk
General
U.
S.
Population
0.019972
<
1
0.004113
4
All
Infants
(<
1
year
old)
0.066430
2
0.010003
10
Children
1­
2
years
old
0.033427
1
0.007954
8
Children
3­
5
years
old
0.029665
<
1
0.007160
7
Children
6­
12
years
old
0.020708
<
1
0.004914
5
Youth
13­
19
years
old
0.016010
<
1
0.003352
3
Adults
20­
49
years
old
0.017578
<
1
0.003613
4
Adults
50+
years
old
0.015963
<
1
0.003597
4
Females
13­
49
years
old
0.017453
<
1
0.003521
4
N/
A
N/
A
S­
metolachlor
Dietary
Exposure
Assessment
DP
Number:
329632
PCode:
108800/
108801
Page:
9
of
21
VIII.
List
of
Attachments
Attachment
1.
Inputs
for
the
Acute
Dietary
Exposure
Analysis
for
S­
metolachlor
Attachment
2.
Acute
Dietary
Exposure
and
Risk
Estimates
for
S­
metolachlor
Attachment
3.
Inputs
for
the
Chronic
Dietary
Exposure
Analysis
for
S­
metolachlor
Attachment
4.
Chronic
Dietary
Exposure
and
Risk
Estimates
for
S­
metolachlor
S­
metolachlor
Dietary
Exposure
Assessment
DP
Number:
329632
PCode:
108800/
108801
Page:
10
of
21
Attachment
1.
Inputs
for
the
Acute
Dietary
Exposure
Analysis
for
S­
metolachlor
Filename:
E:\
working\
s­
metolachlor\
108801a.
R98
Chemical:
Metolachlor
and
S­
metolachlor
RfD(
Chronic):
.1
mg/
kg
bw/
day
NOEL(
Chronic):
9.7
mg/
kg
bw/
day
RfD(
Acute):
3
mg/
kg
bw/
day
NOEL(
Acute):
300
mg/
kg
bw/
day
Date
created/
last
modified:
06­
16­
2006/
09:
15:
23/
8
Program
ver.
2.03
­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­
EPA
Crop
Def
Res
Adj.
Factors
Comment
Code
Grp
Commodity
Name
(
ppm)
#
1
#
2
­­­­­­­­
­­­­
­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­
­­­­­­­­­­
­­­­­­
­­­­­­
­­­­­­­
14000030
14
Almond
0.100000
1.000
1.000
14000031
14
Almond­
babyfood
0.100000
1.000
1.000
14000040
14
Almond,
oil
0.100000
1.000
1.000
14000041
14
Almond,
oil­
babyfood
0.100000
1.000
1.000
12000120
12
Apricot
0.100000
1.000
1.000
12000121
12
Apricot­
babyfood
0.100000
1.000
1.000
12000130
12
Apricot,
dried
0.100000
1.000
1.000
12000140
12
Apricot,
juice
0.100000
1.000
1.000
12000141
12
Apricot,
juice­
babyfood
0.100000
1.000
1.000
01030150
1CD
Arrowroot,
flour
0.200000
1.000
1.000
01030151
1CD
Arrowroot,
flour­
babyfood
0.200000
1.000
1.000
01030170
1CD
Artichoke,
Jerusalem
0.200000
1.000
1.000
95000190
O
Asparagus
0.100000
1.000
1.000
New
us
Full
comment:
New
use
(
PP
9E6055).
15000250
15
Barley,
pearled
barley
0.100000
1.000
1.000
15000251
15
Barley,
pearled
barley­
babyfood
0.100000
1.000
1.000
15000260
15
Barley,
flour
0.100000
1.000
1.000
15000261
15
Barley,
flour­
babyfood
0.100000
1.000
1.000
15000270
15
Barley,
bran
0.100000
1.000
1.000
06030300
6C
Bean,
black,
seed
0.300000
1.000
1.000
06020310
6B
Bean,
broad,
succulent
0.300000
1.000
1.000
Additi
Full
comment:
Additional
data
required.
06030320
6C
Bean,
broad,
seed
0.300000
1.000
1.000
06020330
6B
Bean,
cowpea,
succulent
0.300000
1.000
1.000
Additi
Full
comment:
Additional
data
required.
06030340
6C
Bean,
cowpea,
seed
0.300000
1.000
1.000
06030350
6C
Bean,
great
northern,
seed
0.300000
1.000
1.000
06030360
6C
Bean,
kidney,
seed
0.300000
1.000
1.000
06020370
6B
Bean,
lima,
succulent
0.300000
1.000
1.000
Additi
Full
comment:
Additional
data
required.
06030380
6C
Bean,
lima,
seed
0.300000
1.000
1.000
06030390
6C
Bean,
mung,
seed
0.300000
1.000
1.000
06030400
6C
Bean,
navy,
seed
0.300000
1.000
1.000
06030410
6C
Bean,
pink,
seed
0.300000
1.000
1.000
06030420
6C
Bean,
pinto,
seed
0.300000
1.000
1.000
06010430
6A
Bean,
snap,
succulent
0.300000
1.000
1.000
Additi
Full
comment:
Additional
data
required.
06010431
6A
Bean,
snap,
succulent­
babyfood
0.300000
1.000
1.000
Additi
Full
comment:
Additional
data
required.
21000440
M
Beef,
meat
0.040000
1.000
1.000
21000441
M
Beef,
meat­
babyfood
0.040000
1.000
1.000
21000450
M
Beef,
meat,
dried
0.040000
1.920
1.000
21000460
M
Beef,
meat
byproducts
0.040000
1.000
1.000
21000461
M
Beef,
meat
byproducts­
babyfood
0.040000
1.000
1.000
21000470
M
Beef,
fat
0.040000
1.000
1.000
21000471
M
Beef,
fat­
babyfood
0.040000
1.000
1.000
21000480
M
Beef,
kidney
0.200000
1.000
1.000
21000490
M
Beef,
liver
0.100000
1.000
1.000
21000491
M
Beef,
liver­
babyfood
0.100000
1.000
1.000
01010500
1AB
Beet,
garden,
roots
0.300000
1.000
1.000
01010501
1AB
Beet,
garden,
roots­
babyfood
0.300000
1.000
1.000
02000510
2
Beet,
garden,
tops
1.000000
1.000
1.000
01010520
1A
Beet,
sugar
0.500000
1.000
1.000
New
us
Full
comment:
New
use
(
PP
7F4897).
01010521
1A
Beet,
sugar­
babyfood
0.500000
1.000
1.000
New
us
Full
comment:
New
use
(
PP
7F4897).
01010530
1A
Beet,
sugar,
molasses
2.000000
1.000
1.000
New
us
Full
comment:
New
use
(
PP
7F4897).
01010531
1A
Beet,
sugar,
molasses­
babyfood
2.000000
1.000
1.000
New
us
Full
comment:
New
use
(
PP
7F4897).
14000590
14
Brazil
nut
0.100000
1.000
1.000
05010610
5A
Broccoli
0.600000
1.000
1.000
S­
metolachlor
Dietary
Exposure
Assessment
DP
Number:
329632
PCode:
108800/
108801
Page:
11
of
21
05010611
5A
Broccoli­
babyfood
0.600000
1.000
1.000
05010620
5A
Broccoli,
Chinese
0.600000
1.000
1.000
05010640
5A
Brussels
sprouts
0.600000
1.000
1.000
15000650
15
Buckwheat
0.100000
1.000
1.000
Additi
Full
comment:
Additional
data
required.
15000660
15
Buckwheat,
flour
0.100000
1.000
1.000
Additi
Full
comment:
Additional
data
required.
01010670
1AB
Burdock
0.300000
1.000
1.000
14000680
14
Butternut
0.100000
1.000
1.000
05010690
5A
Cabbage
1.000000
1.000
1.000
05020700
5B
Cabbage,
Chinese,
bok
choy
1.000000
1.000
1.000
05010710
5A
Cabbage,
Chinese,
napa
1.000000
1.000
1.000
05010720
5A
Cabbage,
Chinese,
mustard
1.000000
1.000
1.000
04020760
4B
Cardoon
0.100000
1.000
1.000
01010780
1AB
Carrot
0.300000
1.000
1.000
01010781
1AB
Carrot­
babyfood
0.300000
1.000
1.000
01010790
1AB
Carrot,
juice
0.300000
1.000
1.000
14000810
14
Cashew
0.100000
1.000
1.000
01030820
1CD
Cassava
0.200000
1.000
1.000
01030821
1CD
Cassava­
babyfood
0.200000
1.000
1.000
05010830
5A
Cauliflower
0.600000
1.000
1.000
01010840
1AB
Celeriac
0.300000
1.000
1.000
04020850
4B
Celery
0.100000
1.000
1.000
04020851
4B
Celery­
babyfood
0.100000
1.000
1.000
04020860
4B
Celery,
juice
0.100000
1.000
1.000
04020870
4B
Celtuce
0.100000
1.000
1.000
12000900
12
Cherry
0.100000
1.000
1.000
12000901
12
Cherry­
babyfood
0.100000
1.000
1.000
12000910
12
Cherry,
juice
0.100000
1.000
1.000
12000911
12
Cherry,
juice­
babyfood
0.100000
1.000
1.000
14000920
14
Chestnut
0.100000
1.000
1.000
40000930
P
Chicken,
meat
0.040000
1.000
1.000
40000931
P
Chicken,
meat­
babyfood
0.040000
1.000
1.000
40000940
P
Chicken,
liver
0.050000
1.000
1.000
40000950
P
Chicken,
meat
byproducts
0.040000
1.000
1.000
40000951
P
Chicken,
meat
byproducts­
babyfoo
0.040000
1.000
1.000
40000960
P
Chicken,
fat
0.040000
1.000
1.000
40000961
P
Chicken,
fat­
babyfood
0.040000
1.000
1.000
40000970
P
Chicken,
skin
0.040000
1.000
1.000
40000971
P
Chicken,
skin­
babyfood
0.040000
1.000
1.000
06030980
6C
Chickpea,
seed
0.300000
1.000
1.000
06030981
6C
Chickpea,
seed­
babyfood
0.300000
1.000
1.000
06030990
6C
Chickpea,
flour
0.300000
1.000
1.000
01011000
1AB
Chicory,
roots
0.300000
1.000
1.000
05021170
5B
Collards
1.000000
1.000
1.000
19011180
19A
Coriander,
leaves
1.000000
1.000
1.000
19011181
19A
Coriander,
leaves­
babyfood
1.000000
1.000
1.000
19021190
19B
Coriander,
seed
1.000000
1.000
1.000
19021191
19B
Coriander,
seed­
babyfood
1.000000
1.000
1.000
15001200
15
Corn,
field,
flour
0.100000
1.000
1.000
15001201
15
Corn,
field,
flour­
babyfood
0.100000
1.000
1.000
15001210
15
Corn,
field,
meal
0.100000
1.000
1.000
15001211
15
Corn,
field,
meal­
babyfood
0.100000
1.000
1.000
15001220
15
Corn,
field,
bran
0.100000
1.000
1.000
15001230
15
Corn,
field,
starch
0.100000
1.000
1.000
15001231
15
Corn,
field,
starch­
babyfood
0.100000
1.000
1.000
15001240
15
Corn,
field,
syrup
0.100000
1.500
1.000
15001241
15
Corn,
field,
syrup­
babyfood
0.100000
1.500
1.000
15001250
15
Corn,
field,
oil
0.100000
1.000
1.000
15001251
15
Corn,
field,
oil­
babyfood
0.100000
1.000
1.000
15001260
15
Corn,
pop
0.100000
1.000
1.000
15001270
15
Corn,
sweet
0.100000
1.000
1.000
15001271
15
Corn,
sweet­
babyfood
0.100000
1.000
1.000
95001280
O
Cottonseed,
oil
0.100000
1.000
1.000
95001281
O
Cottonseed,
oil­
babyfood
0.100000
1.000
1.000
01031390
1CD
Dasheen,
corm
0.200000
1.000
1.000
70001450
P
Egg,
whole
0.040000
1.000
1.000
70001451
P
Egg,
whole­
babyfood
0.040000
1.000
1.000
70001460
P
Egg,
white
0.040000
1.000
1.000
70001461
P
Egg,
white
(
solids)­
babyfood
0.040000
1.000
1.000
70001470
P
Egg,
yolk
0.040000
1.000
1.000
70001471
P
Egg,
yolk­
babyfood
0.040000
1.000
1.000
08001480
8
Eggplant
0.100000
1.000
1.000
04021520
4B
Fennel,
Florence
0.100000
1.000
1.000
S­
metolachlor
Dietary
Exposure
Assessment
DP
Number:
329632
PCode:
108800/
108801
Page:
12
of
21
14001550
14
Filbert
0.100000
1.000
1.000
14001560
14
Filbert,
oil
0.100000
1.000
1.000
03001640
3
Garlic
0.100000
1.000
1.000
03001650
3
Garlic,
dried
0.100000
9.000
1.000
03001651
3
Garlic,
dried­
babyfood
0.100000
9.000
1.000
01031660
1CD
Ginger
0.200000
1.000
1.000
01031661
1CD
Ginger­
babyfood
0.200000
1.000
1.000
01031670
1CD
Ginger,
dried
0.200000
1.000
1.000
01011680
1AB
Ginseng,
dried
0.300000
1.000
1.000
23001690
M
Goat,
meat
0.040000
1.000
1.000
23001700
M
Goat,
meat
byproducts
0.040000
1.000
1.000
23001710
M
Goat,
fat
0.040000
1.000
1.000
23001720
M
Goat,
kidney
0.200000
1.000
1.000
23001730
M
Goat,
liver
0.100000
1.000
1.000
06031820
6C
Guar,
seed
0.300000
1.000
1.000
06031821
6C
Guar,
seed­
babyfood
0.300000
1.000
1.000
14001850
14
Hickory
nut
0.100000
1.000
1.000
24001890
M
Horse,
meat
0.040000
1.000
1.000
01011900
1AB
Horseradish
0.300000
1.000
1.000
05021940
5B
Kale
1.000000
1.000
1.000
05011960
5A
Kohlrabi
0.600000
1.000
1.000
03001980
3
Leek
0.100000
1.000
1.000
06032030
6C
Lentil,
seed
0.300000
1.000
1.000
14002130
14
Macadamia
nut
0.100000
1.000
1.000
27002220
D
Milk,
fat
0.020000
1.000
1.000
27002221
D
Milk,
fat
­
baby
food/
infant
for
0.020000
1.000
1.000
27012230
D
Milk,
nonfat
solids
0.020000
1.000
1.000
27012231
D
Milk,
nonfat
solids­
baby
food/
in
0.020000
1.000
1.000
27022240
D
Milk,
water
0.020000
1.000
1.000
27022241
D
Milk,
water­
babyfood/
infant
form
0.020000
1.000
1.000
27032251
D
Milk,
sugar
(
lactose)­
baby
food/
0.020000
1.000
1.000
15002260
15
Millet,
grain
0.100000
1.000
1.000
05022290
5B
Mustard
greens
1.000000
1.000
1.000
12002300
12
Nectarine
0.100000
1.000
1.000
15002310
15
Oat,
bran
0.100000
1.000
1.000
15002320
15
Oat,
flour
0.100000
1.000
1.000
15002321
15
Oat,
flour­
babyfood
0.100000
1.000
1.000
15002330
15
Oat,
groats/
rolled
oats
0.100000
1.000
1.000
15002331
15
Oat,
groats/
rolled
oats­
babyfood
0.100000
1.000
1.000
08002340
8
Okra
0.100000
1.000
1.000
03002370
3
Onion,
dry
bulb
1.000000
1.000
1.000
03002371
3
Onion,
dry
bulb­
babyfood
1.000000
1.000
1.000
03002380
3
Onion,
dry
bulb,
dried
1.000000
9.000
1.000
03002381
3
Onion,
dry
bulb,
dried­
babyfood
1.000000
9.000
1.000
03002390
3
Onion,
green
2.000000
1.000
1.000
Change
Full
comment:
Change
from
0.2
due
to
shorter
PHI
01012500
1AB
Parsley,
turnip
rooted
0.300000
1.000
1.000
01012510
1AB
Parsnip
0.300000
1.000
1.000
01012511
1AB
Parsnip­
babyfood
0.300000
1.000
1.000
06022550
6B
Pea,
succulent
0.300000
1.000
1.000
Additi
Full
comment:
Additional
data
required.
06022551
6B
Pea,
succulent­
babyfood
0.300000
1.000
1.000
Additi
Full
comment:
Additional
data
required.
06032560
6C
Pea,
dry
0.300000
1.000
1.000
06032561
6C
Pea,
dry­
babyfood
0.300000
1.000
1.000
06012570
6A
Pea,
edible
podded,
succulent
0.300000
1.000
1.000
Additi
Full
comment:
Additional
data
required.
06032580
6C
Pea,
pigeon,
seed
0.300000
1.000
1.000
06022590
6B
Pea,
pigeon,
succulent
0.300000
1.000
1.000
Additi
Full
comment:
Additional
data
required.
12002600
12
Peach
0.100000
1.000
1.000
12002601
12
Peach­
babyfood
0.100000
1.000
1.000
12002610
12
Peach,
dried
0.100000
1.000
1.000
12002611
12
Peach,
dried­
babyfood
0.100000
1.000
1.000
12002620
12
Peach,
juice
0.100000
1.000
1.000
12002621
12
Peach,
juice­
babyfood
0.100000
1.000
1.000
95002630
O
Peanut
0.500000
1.000
1.000
95002640
O
Peanut,
butter
0.500000
1.890
1.000
95002650
O
Peanut,
oil
0.500000
1.000
1.000
14002690
14
Pecan
0.100000
1.000
1.000
08002700
8
Pepper,
bell
0.100000
1.000
1.000
08002701
8
Pepper,
bell­
babyfood
0.100000
1.000
1.000
08002710
8
Pepper,
bell,
dried
0.100000
1.000
1.000
08002711
8
Pepper,
bell,
dried­
babyfood
0.100000
1.000
1.000
S­
metolachlor
Dietary
Exposure
Assessment
DP
Number:
329632
PCode:
108800/
108801
Page:
13
of
21
08002720
8
Pepper,
nonbell
0.500000
1.000
1.000
Tabasc
Full
comment:
Tabasco
peppers
@
0.5
ppm
08002721
8
Pepper,
nonbell­
babyfood
0.500000
1.000
1.000
Tabasc
Full
comment:
Tabasco
peppers
@
0.5
ppm
08002730
8
Pepper,
nonbell,
dried
0.500000
1.000
1.000
Tabasc
Full
comment:
Tabasco
peppers
@
0.5
ppm
19022740
19B
Pepper,
black
and
white
0.500000
1.000
1.000
New
us
Full
comment:
New
use
(
PP
4E4420).
19022741
19B
Pepper,
black
and
white­
babyfood
0.500000
1.000
1.000
New
us
Full
comment:
New
use
(
PP
4E4420).
14002820
14
Pistachio
0.100000
1.000
1.000
12002850
12
Plum
0.100000
1.000
1.000
12002851
12
Plum­
babyfood
0.100000
1.000
1.000
12002860
12
Plum,
prune,
fresh
0.100000
1.000
1.000
12002861
12
Plum,
prune,
fresh­
babyfood
0.100000
1.000
1.000
12002870
12
Plum,
prune,
dried
0.100000
1.000
1.000
12002871
12
Plum,
prune,
dried­
babyfood
0.100000
1.000
1.000
12002880
12
Plum,
prune,
juice
0.100000
1.000
1.000
12002881
12
Plum,
prune,
juice­
babyfood
0.100000
1.000
1.000
01032960
1C
Potato,
chips
0.200000
1.000
1.000
01032970
1C
Potato,
dry
(
granules/
flakes)
0.200000
6.500
1.000
01032971
1C
Potato,
dry
(
granules/
flakes)­
b
0.200000
6.500
1.000
01032980
1C
Potato,
flour
0.200000
1.000
1.000
01032981
1C
Potato,
flour­
babyfood
0.200000
1.000
1.000
01032990
1C
Potato,
tuber,
w/
peel
0.200000
1.000
1.000
01032991
1C
Potato,
tuber,
w/
peel­
babyfood
0.200000
1.000
1.000
01033000
1C
Potato,
tuber,
w/
o
peel
0.200000
1.000
1.000
01033001
1C
Potato,
tuber,
w/
o
peel­
babyfood
0.200000
1.000
1.000
60003010
P
Poultry,
other,
meat
0.040000
1.000
1.000
60003020
P
Poultry,
other,
liver
0.050000
1.000
1.000
60003030
P
Poultry,
other,
meat
byproducts
0.040000
1.000
1.000
60003040
P
Poultry,
other,
fat
0.040000
1.000
1.000
60003050
P
Poultry,
other,
skin
0.040000
1.000
1.000
09023080
9B
Pumpkin
0.100000
1.000
1.000
09023090
9B
Pumpkin,
seed
0.100000
1.000
1.000
01013140
1AB
Radish,
roots
0.300000
1.000
1.000
01013160
1AB
Radish,
Oriental,
roots
0.300000
1.000
1.000
04023220
4B
Rhubarb
0.100000
1.000
1.000
15003230
15
Rice,
white
0.100000
1.000
1.000
15003231
15
Rice,
white­
babyfood
0.100000
1.000
1.000
15003240
15
Rice,
brown
0.100000
1.000
1.000
15003241
15
Rice,
brown­
babyfood
0.100000
1.000
1.000
15003250
15
Rice,
flour
0.100000
1.000
1.000
15003251
15
Rice,
flour­
babyfood
0.100000
1.000
1.000
15003260
15
Rice,
bran
0.100000
1.000
1.000
15003261
15
Rice,
bran­
babyfood
0.100000
1.000
1.000
01013270
1AB
Rutabaga
0.300000
1.000
1.000
15003280
15
Rye,
grain
0.100000
1.000
1.000
15003290
15
Rye,
flour
0.100000
1.000
1.000
20003300
20
Safflower,
oil
0.100000
1.000
1.000
20003301
20
Safflower,
oil­
babyfood
0.100000
1.000
1.000
01013310
1AB
Salsify,
roots
0.300000
1.000
1.000
03003380
3
Shallot
0.100000
1.000
1.000
26003390
M
Sheep,
meat
0.040000
1.000
1.000
26003391
M
Sheep,
meat­
babyfood
0.040000
1.000
1.000
26003400
M
Sheep,
meat
byproducts
0.040000
1.000
1.000
26003410
M
Sheep,
fat
0.040000
1.000
1.000
26003411
M
Sheep,
fat­
babyfood
0.040000
1.000
1.000
26003420
M
Sheep,
kidney
0.200000
1.000
1.000
26003430
M
Sheep,
liver
0.100000
1.000
1.000
15003440
15
Sorghum,
grain
0.300000
1.000
1.000
15003450
15
Sorghum,
syrup
0.300000
1.000
1.000
06003470
6
Soybean,
seed
0.200000
1.000
1.000
06003480
6
Soybean,
flour
0.200000
1.000
1.000
06003481
6
Soybean,
flour­
babyfood
0.200000
1.000
1.000
06003490
6
Soybean,
soy
milk
0.200000
1.000
1.000
06003491
6
Soybean,
soy
milk­
babyfood
or
in
0.200000
1.000
1.000
06003500
6
Soybean,
oil
0.200000
1.000
1.000
06003501
6
Soybean,
oil­
babyfood
0.200000
1.000
1.000
04013550
4A
Spinach
0.500000
1.000
1.000
04013551
4A
Spinach­
babyfood
0.500000
1.000
1.000
09023570
9B
Squash,
winter
0.100000
1.000
1.000
09023571
9B
Squash,
winter­
babyfood
0.100000
1.000
1.000
20003640
20
Sunflower,
seed
0.500000
1.000
1.000
S­
metolachlor
Dietary
Exposure
Assessment
DP
Number:
329632
PCode:
108800/
108801
Page:
14
of
21
20003650
20
Sunflower,
oil
0.500000
1.000
1.000
20003651
20
Sunflower,
oil­
babyfood
0.500000
1.000
1.000
01033660
1CD
Sweet
potato
0.200000
1.000
1.000
01033661
1CD
Sweet
potato­
babyfood
0.200000
1.000
1.000
04023670
4B
Swiss
chard
0.100000
1.000
1.000
01033710
1CD
Tanier,
corm
0.200000
1.000
1.000
08003740
8
Tomatillo
0.100000
1.000
1.000
08003750
8
Tomato
0.100000
1.000
1.000
08003751
8
Tomato­
babyfood
0.100000
1.000
1.000
08003760
8
Tomato,
paste
0.300000
1.000
1.000
08003761
8
Tomato,
paste­
babyfood
0.300000
1.000
1.000
08003770
8
Tomato,
puree
0.100000
1.000
1.000
08003771
8
Tomato,
puree­
babyfood
0.100000
1.000
1.000
08003780
8
Tomato,
dried
0.100000
14.300
1.000
08003781
8
Tomato,
dried­
babyfood
0.100000
14.300
1.000
08003790
8
Tomato,
juice
0.100000
1.500
1.000
95003800
O
Tomato,
Tree
0.100000
1.000
1.000
15003810
15
Triticale,
flour
0.100000
1.000
1.000
15003811
15
Triticale,
flour­
babyfood
0.100000
1.000
1.000
50003820
P
Turkey,
meat
0.040000
1.000
1.000
50003821
P
Turkey,
meat­
babyfood
0.040000
1.000
1.000
50003830
P
Turkey,
liver
0.050000
1.000
1.000
50003831
P
Turkey,
liver­
babyfood
0.050000
1.000
1.000
50003840
P
Turkey,
meat
byproducts
0.040000
1.000
1.000
50003841
P
Turkey,
meat
byproducts­
babyfood
0.040000
1.000
1.000
50003850
P
Turkey,
fat
0.040000
1.000
1.000
50003851
P
Turkey,
fat­
babyfood
0.040000
1.000
1.000
50003860
P
Turkey,
skin
0.040000
1.000
1.000
50003861
P
Turkey,
skin­
babyfood
0.040000
1.000
1.000
01033870
1CD
Turmeric
0.200000
1.000
1.000
01013880
1AB
Turnip,
roots
0.300000
1.000
1.000
14003910
14
Walnut
0.100000
1.000
1.000
86010000
O
Water,
direct,
all
sources
0.322000
1.000
1.000
86020000
O
Water,
indirect,
all
sources
0.322000
1.000
1.000
15004010
15
Wheat,
grain
0.100000
1.000
1.000
15004011
15
Wheat,
grain­
babyfood
0.100000
1.000
1.000
15004020
15
Wheat,
flour
0.100000
1.000
1.000
15004021
15
Wheat,
flour­
babyfood
0.100000
1.000
1.000
15004030
15
Wheat,
germ
0.100000
1.000
1.000
15004040
15
Wheat,
bran
0.100000
1.000
1.000
15004050
15
Wild
rice
0.100000
1.000
1.000
01034060
1CD
Yam,
true
0.200000
1.000
1.000
01034070
1CD
Yam
bean
0.200000
1.000
1.000
S­
metolachlor
Dietary
Exposure
Assessment
DP
Number:
329632
PCode:
108800/
108801
Page:
15
of
21
Attachment
2.
Acute
Dietary
Exposure
and
Risk
Estimates
for
S­
metolachlor.

U.
S.
Environmental
Protection
Agency
Ver.
2.02
DEEM­
FCID
ACUTE
Analysis
for
METOLACHLOR
AND
S­
METOLACHLOR
(
1994­
98
data)
Residue
file:
108801a.
R98
Adjustment
factor
#
2
NOT
used.
Analysis
Date:
06­
26­
2006/
11:
24:
09
Residue
file
dated:
06­
26­
2006/
11:
20:
29/
8
NOEL
(
Acute)
=
300.000000
mg/
kg
body­
wt/
day
Daily
totals
for
food
and
foodform
consumption
used.
Run
Comment:
""
===============================================================================

Summary
calculations
(
per
capita):

95th
Percentile
99th
Percentile
99.9th
Percentile
Exposure
%
aRfD
MOE
Exposure
%
aRfD
MOE
Exposure
%
aRfD
MOE
­­­­­­­­­­
­­­­­­­
­­­­­­­­
­­­­­­­­­­
­­­­­­­
­­­­­­­­
­­­­­­­­­­
­­­­­­­
­­­­­­­­
U.
S.
Population:
0.019972
0.67
15021
0.035124
1.17
8541
0.065895
2.20
4552
All
infants:
0.066430
2.21
4516
0.094323
3.14
3180
0.164504
5.48
1823
Children
1­
2
yrs:
0.033427
1.11
8974
0.050375
1.68
5955
0.071410
2.38
4201
Children
3­
5
yrs:
0.029665
0.99
10112
0.043437
1.45
6906
0.066670
2.22
4499
Children
6­
12
yrs:
0.020708
0.69
14487
0.032559
1.09
9213
0.044065
1.47
6808
Youth
13­
19
yrs:
0.016010
0.53
18738
0.025329
0.84
11844
0.042886
1.43
6995
Adults
20­
49
yrs:
0.017578
0.59
17067
0.028212
0.94
10633
0.049895
1.66
6012
Adults
50+
yrs:
0.015963
0.53
18793
0.022499
0.75
13333
0.035428
1.18
8467
Females
13­
49
yrs:
0.017453
0.58
17189
0.028013
0.93
10709
0.048961
1.63
6127
S­
metolachlor
Dietary
Exposure
Assessment
DP
Number:
329632
PCode:
108800/
108801
Page:
16
of
21
Attachment
3.
Inputs
for
the
Chronic
Dietary
Exposure
Analysis
for
S­
metolachlor
Filename:
E:\
working\
s­
metolachlor\
108801c.
R98
Chemical:
Metolachlor
and
S­
metolachlor
RfD(
Chronic):
.1
mg/
kg
bw/
day
NOEL(
Chronic):
9.7
mg/
kg
bw/
day
RfD(
Acute):
3
mg/
kg
bw/
day
NOEL(
Acute):
300
mg/
kg
bw/
day
Date
created/
last
modified:
06­
16­
2006/
09:
16:
43/
8
Program
ver.
2.03
­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­
EPA
Crop
Def
Res
Adj.
Factors
Comment
Code
Grp
Commodity
Name
(
ppm)
#
1
#
2
­­­­­­­­
­­­­
­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­
­­­­­­­­­­
­­­­­­
­­­­­­
­­­­­­­
14000030
14
Almond
0.100000
1.000
1.000
14000031
14
Almond­
babyfood
0.100000
1.000
1.000
14000040
14
Almond,
oil
0.100000
1.000
1.000
14000041
14
Almond,
oil­
babyfood
0.100000
1.000
1.000
12000120
12
Apricot
0.100000
1.000
1.000
12000121
12
Apricot­
babyfood
0.100000
1.000
1.000
12000130
12
Apricot,
dried
0.100000
1.000
1.000
12000140
12
Apricot,
juice
0.100000
1.000
1.000
12000141
12
Apricot,
juice­
babyfood
0.100000
1.000
1.000
01030150
1CD
Arrowroot,
flour
0.200000
1.000
1.000
01030151
1CD
Arrowroot,
flour­
babyfood
0.200000
1.000
1.000
01030170
1CD
Artichoke,
Jerusalem
0.200000
1.000
1.000
95000190
O
Asparagus
0.100000
1.000
1.000
New
us
Full
comment:
New
use
(
PP
9E6055).
15000250
15
Barley,
pearled
barley
0.100000
1.000
1.000
15000251
15
Barley,
pearled
barley­
babyfood
0.100000
1.000
1.000
15000260
15
Barley,
flour
0.100000
1.000
1.000
15000261
15
Barley,
flour­
babyfood
0.100000
1.000
1.000
15000270
15
Barley,
bran
0.100000
1.000
1.000
06030300
6C
Bean,
black,
seed
0.300000
1.000
1.000
06020310
6B
Bean,
broad,
succulent
0.300000
1.000
1.000
Additi
Full
comment:
Additional
data
required.
06030320
6C
Bean,
broad,
seed
0.300000
1.000
1.000
06020330
6B
Bean,
cowpea,
succulent
0.300000
1.000
1.000
Additi
Full
comment:
Additional
data
required.
06030340
6C
Bean,
cowpea,
seed
0.300000
1.000
1.000
06030350
6C
Bean,
great
northern,
seed
0.300000
1.000
1.000
06030360
6C
Bean,
kidney,
seed
0.300000
1.000
1.000
06020370
6B
Bean,
lima,
succulent
0.300000
1.000
1.000
Additi
Full
comment:
Additional
data
required.
06030380
6C
Bean,
lima,
seed
0.300000
1.000
1.000
06030390
6C
Bean,
mung,
seed
0.300000
1.000
1.000
06030400
6C
Bean,
navy,
seed
0.300000
1.000
1.000
06030410
6C
Bean,
pink,
seed
0.300000
1.000
1.000
06030420
6C
Bean,
pinto,
seed
0.300000
1.000
1.000
06010430
6A
Bean,
snap,
succulent
0.300000
1.000
1.000
Additi
Full
comment:
Additional
data
required.
06010431
6A
Bean,
snap,
succulent­
babyfood
0.300000
1.000
1.000
Additi
Full
comment:
Additional
data
required.
21000440
M
Beef,
meat
0.040000
1.000
1.000
21000441
M
Beef,
meat­
babyfood
0.040000
1.000
1.000
21000450
M
Beef,
meat,
dried
0.040000
1.920
1.000
21000460
M
Beef,
meat
byproducts
0.040000
1.000
1.000
21000461
M
Beef,
meat
byproducts­
babyfood
0.040000
1.000
1.000
21000470
M
Beef,
fat
0.040000
1.000
1.000
21000471
M
Beef,
fat­
babyfood
0.040000
1.000
1.000
21000480
M
Beef,
kidney
0.200000
1.000
1.000
21000490
M
Beef,
liver
0.100000
1.000
1.000
21000491
M
Beef,
liver­
babyfood
0.100000
1.000
1.000
01010500
1AB
Beet,
garden,
roots
0.300000
1.000
1.000
01010501
1AB
Beet,
garden,
roots­
babyfood
0.300000
1.000
1.000
02000510
2
Beet,
garden,
tops
1.000000
1.000
1.000
01010520
1A
Beet,
sugar
0.500000
1.000
1.000
New
us
Full
comment:
New
use
(
PP
7F4897).
01010521
1A
Beet,
sugar­
babyfood
0.500000
1.000
1.000
New
us
Full
comment:
New
use
(
PP
7F4897).
01010530
1A
Beet,
sugar,
molasses
2.000000
1.000
1.000
New
us
Full
comment:
New
use
(
PP
7F4897).
01010531
1A
Beet,
sugar,
molasses­
babyfood
2.000000
1.000
1.000
New
us
Full
comment:
New
use
(
PP
7F4897).
14000590
14
Brazil
nut
0.100000
1.000
1.000
05010610
5A
Broccoli
0.600000
1.000
1.000
S­
metolachlor
Dietary
Exposure
Assessment
DP
Number:
329632
PCode:
108800/
108801
Page:
17
of
21
05010611
5A
Broccoli­
babyfood
0.600000
1.000
1.000
05010620
5A
Broccoli,
Chinese
0.600000
1.000
1.000
05010640
5A
Brussels
sprouts
0.600000
1.000
1.000
15000650
15
Buckwheat
0.100000
1.000
1.000
Additi
Full
comment:
Additional
data
required.
15000660
15
Buckwheat,
flour
0.100000
1.000
1.000
Additi
Full
comment:
Additional
data
required.
01010670
1AB
Burdock
0.300000
1.000
1.000
14000680
14
Butternut
0.100000
1.000
1.000
05010690
5A
Cabbage
1.000000
1.000
1.000
05020700
5B
Cabbage,
Chinese,
bok
choy
1.000000
1.000
1.000
05010710
5A
Cabbage,
Chinese,
napa
1.000000
1.000
1.000
05010720
5A
Cabbage,
Chinese,
mustard
1.000000
1.000
1.000
04020760
4B
Cardoon
0.100000
1.000
1.000
01010780
1AB
Carrot
0.300000
1.000
1.000
01010781
1AB
Carrot­
babyfood
0.300000
1.000
1.000
01010790
1AB
Carrot,
juice
0.300000
1.000
1.000
14000810
14
Cashew
0.100000
1.000
1.000
01030820
1CD
Cassava
0.200000
1.000
1.000
01030821
1CD
Cassava­
babyfood
0.200000
1.000
1.000
05010830
5A
Cauliflower
0.600000
1.000
1.000
01010840
1AB
Celeriac
0.300000
1.000
1.000
04020850
4B
Celery
0.100000
1.000
1.000
04020851
4B
Celery­
babyfood
0.100000
1.000
1.000
04020860
4B
Celery,
juice
0.100000
1.000
1.000
04020870
4B
Celtuce
0.100000
1.000
1.000
12000900
12
Cherry
0.100000
1.000
1.000
12000901
12
Cherry­
babyfood
0.100000
1.000
1.000
12000910
12
Cherry,
juice
0.100000
1.000
1.000
12000911
12
Cherry,
juice­
babyfood
0.100000
1.000
1.000
14000920
14
Chestnut
0.100000
1.000
1.000
40000930
P
Chicken,
meat
0.040000
1.000
1.000
40000931
P
Chicken,
meat­
babyfood
0.040000
1.000
1.000
40000940
P
Chicken,
liver
0.050000
1.000
1.000
40000950
P
Chicken,
meat
byproducts
0.040000
1.000
1.000
40000951
P
Chicken,
meat
byproducts­
babyfoo
0.040000
1.000
1.000
40000960
P
Chicken,
fat
0.040000
1.000
1.000
40000961
P
Chicken,
fat­
babyfood
0.040000
1.000
1.000
40000970
P
Chicken,
skin
0.040000
1.000
1.000
40000971
P
Chicken,
skin­
babyfood
0.040000
1.000
1.000
06030980
6C
Chickpea,
seed
0.300000
1.000
1.000
06030981
6C
Chickpea,
seed­
babyfood
0.300000
1.000
1.000
06030990
6C
Chickpea,
flour
0.300000
1.000
1.000
01011000
1AB
Chicory,
roots
0.300000
1.000
1.000
05021170
5B
Collards
1.000000
1.000
1.000
19011180
19A
Coriander,
leaves
1.000000
1.000
1.000
19011181
19A
Coriander,
leaves­
babyfood
1.000000
1.000
1.000
19021190
19B
Coriander,
seed
1.000000
1.000
1.000
19021191
19B
Coriander,
seed­
babyfood
1.000000
1.000
1.000
15001200
15
Corn,
field,
flour
0.100000
1.000
1.000
15001201
15
Corn,
field,
flour­
babyfood
0.100000
1.000
1.000
15001210
15
Corn,
field,
meal
0.100000
1.000
1.000
15001211
15
Corn,
field,
meal­
babyfood
0.100000
1.000
1.000
15001220
15
Corn,
field,
bran
0.100000
1.000
1.000
15001230
15
Corn,
field,
starch
0.100000
1.000
1.000
15001231
15
Corn,
field,
starch­
babyfood
0.100000
1.000
1.000
15001240
15
Corn,
field,
syrup
0.100000
1.500
1.000
15001241
15
Corn,
field,
syrup­
babyfood
0.100000
1.500
1.000
15001250
15
Corn,
field,
oil
0.100000
1.000
1.000
15001251
15
Corn,
field,
oil­
babyfood
0.100000
1.000
1.000
15001260
15
Corn,
pop
0.100000
1.000
1.000
15001270
15
Corn,
sweet
0.100000
1.000
1.000
15001271
15
Corn,
sweet­
babyfood
0.100000
1.000
1.000
95001280
O
Cottonseed,
oil
0.100000
1.000
1.000
95001281
O
Cottonseed,
oil­
babyfood
0.100000
1.000
1.000
01031390
1CD
Dasheen,
corm
0.200000
1.000
1.000
70001450
P
Egg,
whole
0.040000
1.000
1.000
70001451
P
Egg,
whole­
babyfood
0.040000
1.000
1.000
70001460
P
Egg,
white
0.040000
1.000
1.000
70001461
P
Egg,
white
(
solids)­
babyfood
0.040000
1.000
1.000
70001470
P
Egg,
yolk
0.040000
1.000
1.000
70001471
P
Egg,
yolk­
babyfood
0.040000
1.000
1.000
08001480
8
Eggplant
0.100000
1.000
1.000
04021520
4B
Fennel,
Florence
0.100000
1.000
1.000
S­
metolachlor
Dietary
Exposure
Assessment
DP
Number:
329632
PCode:
108800/
108801
Page:
18
of
21
14001550
14
Filbert
0.100000
1.000
1.000
14001560
14
Filbert,
oil
0.100000
1.000
1.000
03001640
3
Garlic
0.100000
1.000
1.000
03001650
3
Garlic,
dried
0.100000
9.000
1.000
03001651
3
Garlic,
dried­
babyfood
0.100000
9.000
1.000
01031660
1CD
Ginger
0.200000
1.000
1.000
01031661
1CD
Ginger­
babyfood
0.200000
1.000
1.000
01031670
1CD
Ginger,
dried
0.200000
1.000
1.000
01011680
1AB
Ginseng,
dried
0.300000
1.000
1.000
23001690
M
Goat,
meat
0.040000
1.000
1.000
23001700
M
Goat,
meat
byproducts
0.040000
1.000
1.000
23001710
M
Goat,
fat
0.040000
1.000
1.000
23001720
M
Goat,
kidney
0.200000
1.000
1.000
23001730
M
Goat,
liver
0.100000
1.000
1.000
06031820
6C
Guar,
seed
0.300000
1.000
1.000
06031821
6C
Guar,
seed­
babyfood
0.300000
1.000
1.000
14001850
14
Hickory
nut
0.100000
1.000
1.000
24001890
M
Horse,
meat
0.040000
1.000
1.000
01011900
1AB
Horseradish
0.300000
1.000
1.000
05021940
5B
Kale
1.000000
1.000
1.000
05011960
5A
Kohlrabi
0.600000
1.000
1.000
03001980
3
Leek
0.100000
1.000
1.000
06032030
6C
Lentil,
seed
0.300000
1.000
1.000
14002130
14
Macadamia
nut
0.100000
1.000
1.000
27002220
D
Milk,
fat
0.020000
1.000
1.000
27002221
D
Milk,
fat
­
baby
food/
infant
for
0.020000
1.000
1.000
27012230
D
Milk,
nonfat
solids
0.020000
1.000
1.000
27012231
D
Milk,
nonfat
solids­
baby
food/
in
0.020000
1.000
1.000
27022240
D
Milk,
water
0.020000
1.000
1.000
27022241
D
Milk,
water­
babyfood/
infant
form
0.020000
1.000
1.000
27032251
D
Milk,
sugar
(
lactose)­
baby
food/
0.020000
1.000
1.000
15002260
15
Millet,
grain
0.100000
1.000
1.000
05022290
5B
Mustard
greens
1.000000
1.000
1.000
12002300
12
Nectarine
0.100000
1.000
1.000
15002310
15
Oat,
bran
0.100000
1.000
1.000
15002320
15
Oat,
flour
0.100000
1.000
1.000
15002321
15
Oat,
flour­
babyfood
0.100000
1.000
1.000
15002330
15
Oat,
groats/
rolled
oats
0.100000
1.000
1.000
15002331
15
Oat,
groats/
rolled
oats­
babyfood
0.100000
1.000
1.000
08002340
8
Okra
0.100000
1.000
1.000
03002370
3
Onion,
dry
bulb
1.000000
1.000
1.000
03002371
3
Onion,
dry
bulb­
babyfood
1.000000
1.000
1.000
03002380
3
Onion,
dry
bulb,
dried
1.000000
9.000
1.000
03002381
3
Onion,
dry
bulb,
dried­
babyfood
1.000000
9.000
1.000
03002390
3
Onion,
green
2.000000
1.000
1.000
Change
Full
comment:
Change
from
0.2
due
to
shorter
PHI
01012500
1AB
Parsley,
turnip
rooted
0.300000
1.000
1.000
01012510
1AB
Parsnip
0.300000
1.000
1.000
01012511
1AB
Parsnip­
babyfood
0.300000
1.000
1.000
06022550
6B
Pea,
succulent
0.300000
1.000
1.000
Additi
Full
comment:
Additional
data
required.
06022551
6B
Pea,
succulent­
babyfood
0.300000
1.000
1.000
Additi
Full
comment:
Additional
data
required.
06032560
6C
Pea,
dry
0.300000
1.000
1.000
06032561
6C
Pea,
dry­
babyfood
0.300000
1.000
1.000
06012570
6A
Pea,
edible
podded,
succulent
0.300000
1.000
1.000
Additi
Full
comment:
Additional
data
required.
06032580
6C
Pea,
pigeon,
seed
0.300000
1.000
1.000
06022590
6B
Pea,
pigeon,
succulent
0.300000
1.000
1.000
Additi
Full
comment:
Additional
data
required.
12002600
12
Peach
0.100000
1.000
1.000
12002601
12
Peach­
babyfood
0.100000
1.000
1.000
12002610
12
Peach,
dried
0.100000
1.000
1.000
12002611
12
Peach,
dried­
babyfood
0.100000
1.000
1.000
12002620
12
Peach,
juice
0.100000
1.000
1.000
12002621
12
Peach,
juice­
babyfood
0.100000
1.000
1.000
95002630
O
Peanut
0.500000
1.000
1.000
95002640
O
Peanut,
butter
0.500000
1.890
1.000
95002650
O
Peanut,
oil
0.500000
1.000
1.000
14002690
14
Pecan
0.100000
1.000
1.000
08002700
8
Pepper,
bell
0.100000
1.000
1.000
08002701
8
Pepper,
bell­
babyfood
0.100000
1.000
1.000
08002710
8
Pepper,
bell,
dried
0.100000
1.000
1.000
08002711
8
Pepper,
bell,
dried­
babyfood
0.100000
1.000
1.000
S­
metolachlor
Dietary
Exposure
Assessment
DP
Number:
329632
PCode:
108800/
108801
Page:
19
of
21
08002720
8
Pepper,
nonbell
0.500000
1.000
1.000
Tabasc
Full
comment:
Tabasco
peppers
@
0.5
ppm
08002721
8
Pepper,
nonbell­
babyfood
0.500000
1.000
1.000
Tabasc
Full
comment:
Tabasco
peppers
@
0.5
ppm
08002730
8
Pepper,
nonbell,
dried
0.500000
1.000
1.000
Tabasc
Full
comment:
Tabasco
peppers
@
0.5
ppm
19022740
19B
Pepper,
black
and
white
0.500000
1.000
1.000
New
us
Full
comment:
New
use
(
PP
4E4420).
19022741
19B
Pepper,
black
and
white­
babyfood
0.500000
1.000
1.000
New
us
Full
comment:
New
use
(
PP
4E4420).
14002820
14
Pistachio
0.100000
1.000
1.000
12002850
12
Plum
0.100000
1.000
1.000
12002851
12
Plum­
babyfood
0.100000
1.000
1.000
12002860
12
Plum,
prune,
fresh
0.100000
1.000
1.000
12002861
12
Plum,
prune,
fresh­
babyfood
0.100000
1.000
1.000
12002870
12
Plum,
prune,
dried
0.100000
1.000
1.000
12002871
12
Plum,
prune,
dried­
babyfood
0.100000
1.000
1.000
12002880
12
Plum,
prune,
juice
0.100000
1.000
1.000
12002881
12
Plum,
prune,
juice­
babyfood
0.100000
1.000
1.000
01032960
1C
Potato,
chips
0.200000
1.000
1.000
01032970
1C
Potato,
dry
(
granules/
flakes)
0.200000
6.500
1.000
01032971
1C
Potato,
dry
(
granules/
flakes)­
b
0.200000
6.500
1.000
01032980
1C
Potato,
flour
0.200000
1.000
1.000
01032981
1C
Potato,
flour­
babyfood
0.200000
1.000
1.000
01032990
1C
Potato,
tuber,
w/
peel
0.200000
1.000
1.000
01032991
1C
Potato,
tuber,
w/
peel­
babyfood
0.200000
1.000
1.000
01033000
1C
Potato,
tuber,
w/
o
peel
0.200000
1.000
1.000
01033001
1C
Potato,
tuber,
w/
o
peel­
babyfood
0.200000
1.000
1.000
60003010
P
Poultry,
other,
meat
0.040000
1.000
1.000
60003020
P
Poultry,
other,
liver
0.050000
1.000
1.000
60003030
P
Poultry,
other,
meat
byproducts
0.040000
1.000
1.000
60003040
P
Poultry,
other,
fat
0.040000
1.000
1.000
60003050
P
Poultry,
other,
skin
0.040000
1.000
1.000
09023080
9B
Pumpkin
0.100000
1.000
1.000
09023090
9B
Pumpkin,
seed
0.100000
1.000
1.000
01013140
1AB
Radish,
roots
0.300000
1.000
1.000
01013160
1AB
Radish,
Oriental,
roots
0.300000
1.000
1.000
04023220
4B
Rhubarb
0.100000
1.000
1.000
15003230
15
Rice,
white
0.100000
1.000
1.000
15003231
15
Rice,
white­
babyfood
0.100000
1.000
1.000
15003240
15
Rice,
brown
0.100000
1.000
1.000
15003241
15
Rice,
brown­
babyfood
0.100000
1.000
1.000
15003250
15
Rice,
flour
0.100000
1.000
1.000
15003251
15
Rice,
flour­
babyfood
0.100000
1.000
1.000
15003260
15
Rice,
bran
0.100000
1.000
1.000
15003261
15
Rice,
bran­
babyfood
0.100000
1.000
1.000
01013270
1AB
Rutabaga
0.300000
1.000
1.000
15003280
15
Rye,
grain
0.100000
1.000
1.000
15003290
15
Rye,
flour
0.100000
1.000
1.000
20003300
20
Safflower,
oil
0.100000
1.000
1.000
20003301
20
Safflower,
oil­
babyfood
0.100000
1.000
1.000
01013310
1AB
Salsify,
roots
0.300000
1.000
1.000
03003380
3
Shallot
0.100000
1.000
1.000
26003390
M
Sheep,
meat
0.040000
1.000
1.000
26003391
M
Sheep,
meat­
babyfood
0.040000
1.000
1.000
26003400
M
Sheep,
meat
byproducts
0.040000
1.000
1.000
26003410
M
Sheep,
fat
0.040000
1.000
1.000
26003411
M
Sheep,
fat­
babyfood
0.040000
1.000
1.000
26003420
M
Sheep,
kidney
0.200000
1.000
1.000
26003430
M
Sheep,
liver
0.100000
1.000
1.000
15003440
15
Sorghum,
grain
0.300000
1.000
1.000
15003450
15
Sorghum,
syrup
0.300000
1.000
1.000
06003470
6
Soybean,
seed
0.200000
1.000
1.000
06003480
6
Soybean,
flour
0.200000
1.000
1.000
06003481
6
Soybean,
flour­
babyfood
0.200000
1.000
1.000
06003490
6
Soybean,
soy
milk
0.200000
1.000
1.000
06003491
6
Soybean,
soy
milk­
babyfood
or
in
0.200000
1.000
1.000
06003500
6
Soybean,
oil
0.200000
1.000
1.000
06003501
6
Soybean,
oil­
babyfood
0.200000
1.000
1.000
04013550
4A
Spinach
0.500000
1.000
1.000
04013551
4A
Spinach­
babyfood
0.500000
1.000
1.000
09023570
9B
Squash,
winter
0.100000
1.000
1.000
09023571
9B
Squash,
winter­
babyfood
0.100000
1.000
1.000
20003640
20
Sunflower,
seed
0.500000
1.000
1.000
S­
metolachlor
Dietary
Exposure
Assessment
DP
Number:
329632
PCode:
108800/
108801
Page:
20
of
21
20003650
20
Sunflower,
oil
0.500000
1.000
1.000
20003651
20
Sunflower,
oil­
babyfood
0.500000
1.000
1.000
01033660
1CD
Sweet
potato
0.200000
1.000
1.000
01033661
1CD
Sweet
potato­
babyfood
0.200000
1.000
1.000
04023670
4B
Swiss
chard
0.100000
1.000
1.000
01033710
1CD
Tanier,
corm
0.200000
1.000
1.000
08003740
8
Tomatillo
0.100000
1.000
1.000
08003750
8
Tomato
0.100000
1.000
1.000
08003751
8
Tomato­
babyfood
0.100000
1.000
1.000
08003760
8
Tomato,
paste
0.300000
1.000
1.000
08003761
8
Tomato,
paste­
babyfood
0.300000
1.000
1.000
08003770
8
Tomato,
puree
0.100000
1.000
1.000
08003771
8
Tomato,
puree­
babyfood
0.100000
1.000
1.000
08003780
8
Tomato,
dried
0.100000
14.300
1.000
08003781
8
Tomato,
dried­
babyfood
0.100000
14.300
1.000
08003790
8
Tomato,
juice
0.100000
1.500
1.000
95003800
O
Tomato,
Tree
0.100000
1.000
1.000
15003810
15
Triticale,
flour
0.100000
1.000
1.000
15003811
15
Triticale,
flour­
babyfood
0.100000
1.000
1.000
50003820
P
Turkey,
meat
0.040000
1.000
1.000
50003821
P
Turkey,
meat­
babyfood
0.040000
1.000
1.000
50003830
P
Turkey,
liver
0.050000
1.000
1.000
50003831
P
Turkey,
liver­
babyfood
0.050000
1.000
1.000
50003840
P
Turkey,
meat
byproducts
0.040000
1.000
1.000
50003841
P
Turkey,
meat
byproducts­
babyfood
0.040000
1.000
1.000
50003850
P
Turkey,
fat
0.040000
1.000
1.000
50003851
P
Turkey,
fat­
babyfood
0.040000
1.000
1.000
50003860
P
Turkey,
skin
0.040000
1.000
1.000
50003861
P
Turkey,
skin­
babyfood
0.040000
1.000
1.000
01033870
1CD
Turmeric
0.200000
1.000
1.000
01013880
1AB
Turnip,
roots
0.300000
1.000
1.000
14003910
14
Walnut
0.100000
1.000
1.000
86010000
O
Water,
direct,
all
sources
0.103000
1.000
1.000
86020000
O
Water,
indirect,
all
sources
0.103000
1.000
1.000
15004010
15
Wheat,
grain
0.100000
1.000
1.000
15004011
15
Wheat,
grain­
babyfood
0.100000
1.000
1.000
15004020
15
Wheat,
flour
0.100000
1.000
1.000
15004021
15
Wheat,
flour­
babyfood
0.100000
1.000
1.000
15004030
15
Wheat,
germ
0.100000
1.000
1.000
15004040
15
Wheat,
bran
0.100000
1.000
1.000
15004050
15
Wild
rice
0.100000
1.000
1.000
01034060
1CD
Yam,
true
0.200000
1.000
1.000
01034070
1CD
Yam
bean
0.200000
1.000
1.000
S­
metolachlor
Dietary
Exposure
Assessment
DP
Number:
329632
PCode:
108800/
108801
Page:
21
of
21
Attachment
4.
Chronic
Dietary
Exposure
and
Risk
Estimates
for
S­
metolachlor.

U.
S.
Environmental
Protection
Agency
Ver.
2.00
DEEM­
FCID
Chronic
analysis
for
METOLACHLOR
AND
S­
METOLACHLOR
(
1994­
98
data)
Residue
file
name:
E:\
working\
s­
metolachlor\
108801c.
R98
Adjustment
factor
#
2
NOT
used.
Analysis
Date
06­
26­
2006/
11:
22:
42
Residue
file
dated:
06­
26­
2006/
11:
21:
48/
8
Reference
dose
(
RfD,
Chronic)
=
.1
mg/
kg
bw/
day
===============================================================================
Total
exposure
by
population
subgroup
­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­

Total
Exposure
­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­
Population
mg/
kg
Percent
of
Subgroup
body
wt/
day
Rfd
­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­
­­­­­­­­­­­­­
­­­­­­­­­­­­­­­
U.
S.
Population
(
total)
0.004113
4.1%

U.
S.
Population
(
spring
season)
0.004084
4.1%
U.
S.
Population
(
summer
season)
0.004253
4.3%
U.
S.
Population
(
autumn
season)
0.004065
4.1%
U.
S.
Population
(
winter
season)
0.004045
4.0%

Northeast
region
0.003872
3.9%
Midwest
region
0.004188
4.2%
Southern
region
0.003947
3.9%
Western
region
0.004511
4.5%

Hispanics
0.004533
4.5%
Non­
hispanic
whites
0.003989
4.0%
Non­
hispanic
blacks
0.004111
4.1%
Non­
hisp/
non­
white/
non­
black
0.005147
5.1%

All
infants
(<
1
year)
0.010003
10.0%
Nursing
infants
0.003972
4.0%
Non­
nursing
infants
0.012292
12.3%
Children
1­
6
yrs
0.007278
7.3%
Children
7­
12
yrs
0.004670
4.7%

Females
13­
19
(
not
preg
or
nursing)
0.003121
3.1%
Females
20+
(
not
preg
or
nursing)
0.003615
3.6%
Females
13­
50
yrs
0.003709
3.7%
Females
13+
(
preg/
not
nursing)
0.003720
3.7%
Females
13+
(
nursing)
0.004986
5.0%

Males
13­
19
yrs
0.003563
3.6%
Males
20+
yrs
0.003581
3.6%
Seniors
55+
0.003584
3.6%

Children
1­
2
yrs
0.007954
8.0%
Children
3­
5
yrs
0.007160
7.2%
Children
6­
12
yrs
0.004914
4.9%
Youth
13­
19
yrs
0.003352
3.4%
Adults
20­
49
yrs
0.003614
3.6%
Adults
50+
yrs
0.003597
3.6%
Females
13­
49
yrs
0.003521
3.5%

­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­­