Document ID: EPA-HQ-OPP-2003-0222-0001
Agency: epa
Document Type: Notice
Title: Issuance of Experimental Use Permits
Posted Date: 2003-08-20T04:00Z

50143
Federal
Register
/
Vol.
68,
No.
161
/
Wednesday,
August
20,
2003
/
Notices
TABLE
4.
 
AGGREGATE
EXPOSURE
OF
DIMETHOMORPH
(
BAS
550
F)
 
Continued
Exposure
Infants
(
0
 
1
years)
Children
(
1
 
6
years)
Males
(
20
 
49
years)
Females
(
13
 
49
years)

Chronic
exposure
(
mg/
kg
bwt/
day)
0.001265
0.000843
0.000361
0.000402
%
aRfD
and
%
aPAD
NA
NA
NA
NA
%
cRfD
and
%
cPAD
25.30
16.87
7.23
8.03
AGGREGATE
Acute
exposure
(
mg/
kg
bwt/
day)
0.174865
0.166243
0.064221
0.073462
Chronic
exposure
(
mg/
kg
bwt/
day)
0.009237
0.015963
0.007214
0.008173
%
aRfD
and
%
aPAD
NA
NA
NA
NA
%
cRfD
and
%
cPAD
33.27
31.99
14.08
15.80
These
results
indicate
the
aggregate
exposure
of
dimethomorph
(
BAS
550
F),
from
potential
residues
in
food
and
drinking
water,
will
not
exceed
EPA's
level
of
concern
(
100%
of
RfD).
Overall,
considering
a
``
worst­
case''
scenario,
we
can
conclude
with
reasonable
certainty
that
no
harm
will
occur
from
either
acute
or
chronic
aggregate
exposure
of
dimethomorph
residues
in
the
current
and
pending
commodities.
3.
Non­
dietary
exposure.
Currently,
there
are
no
registered
residential
uses
for
dimethomorph
in
the
United
States.
Thus,
an
assessment
of
non­
dietary
exposure
is
not
relevant
to
this
petition.

D.
Cumulative
Effects
There
is
no
information
to
indicate
that
any
toxic
effects
produced
by
dimethomorph
would
be
cumulative
with
those
of
any
other
chemical.
The
fungicidal
mode
of
action
of
dimethomorph
is
unique;
dimethomorph
inhibits
cell
wall
formation
only
in
Oomycete
fungi.
The
result
is
lysis
of
the
cell
wall
that
kills
growing
cells
and
inhibits
spore
formation
in
mature
hyphae.
This
unique
mode
of
action
and
limited
pest
spectrum
suggest
that
there
is
little
or
no
potential
for
cumulative
toxic
effects
in
mammals.
In
addition,
the
toxicity
studies
submitted
to
support
this
petition
do
not
indicate
that
dimethomorph
is
a
particularly
toxic
compound.
No
toxic
end­
points
of
potential
concern
were
identified.

E.
Safety
Determination
1.
U.
S.
population.
Based
on
the
acute
toxicity
data,
BASF
believes
that
dimethomorph
does
not
pose
any
acute
dietary
risks.
Therefore,
a
calculation
of
an
acute
RfD
is
not
needed.
The
cPAD
is
0.1
mg/
kg
bwt/
day,
based
on
a
NOAEL
of
approximately
10
mg/
kg
bwt/
day
(
200
ppm)
from
a
2
 
year
dietary
toxicity
study
in
rats
that
demonstrated
decreased
body
weight
and
liver
foci
in
females
at
750
ppm.
The
cPAD
is
calculated
using
an
uncertainty
factor
of
100.
The
theoretical
maximum
residue
concentration
(
TMRC)
for
all
commodities
covered
in
this
petition
is
estimated
at
0.003
mg/
kg
bwt/
day
for
the
general
population.
This
represents
a
dietary
exposure
to
the
general
population
of
the
United
States
that
is
3.0%
of
the
cPAD.
The
combined
TMRC
for
all
current
and
pending
dimethomorph
tolerances
in
potatoes,
tomatoes,
grapes,
hops,
cereal
grain
commodities,
lettuce
(
head
and
leaf),
endive
(
escarole),
radichio,
cucurbit
vegetables
(
crop
group
9),
bulb
vegetables
(
crop
group
3),
and
fruiting
vegetables
(
except
cucurbits)
(
crop
group
8)
will
utilize
less
than
10%
of
the
cPAD
for
the
general
U.
S.
population.
Since
EPA
generally
has
no
concern
for
exposures
below
100
percent
of
the
cPAD,
EPA
should
conclude
that
there
is
a
reasonable
certainty
that
no
harm
will
result
from
aggregate
exposure
to
dimethomorph
residues
in
or
on
commodities
of
the
cited
crops.
2.
Infants
and
children.
The
TMRC
for
all
commodities
covered
in
this
petition
is
minimal.
The
consumption
of
residues
of
dimethomorph
on
commodities
associated
with
this
request
will
use
approximately
7.0%
of
the
cPAD
for
children
ages
1
 
6.
Moreover,
the
combined
TMRC
values
for
all
current
and
pending
dimethomorph
tolerances
will
utilize
less
than
10%
of
the
cPAD
for
each
of
the
subgroups.
The
results
of
the
studies
submitted
to
support
this
package
provide
no
evidence
that
dimethomorph
caused
reproductive,
developmental
or
fetotoxic
effects.
No
such
effects
were
noted
at
dose
levels
that
were
not
maternally
toxic.
The
NOAELs
observed
in
the
developmental
and
reproductive
studies
were
6
to
65
times
higher
than
the
NOAEL
used
to
establish
the
cPAD.
There
is
no
evidence
to
indicate
that
children
or
infants
would
be
more
sensitive
than
adults
to
toxic
effects
caused
by
exposure
to
dimethomorph.
Therefore,
the
registrant
believes
that
the
results
of
the
toxicology
and
metabolism
studies
support
both
the
safety
of
dimethomorph
to
humans
based
on
the
intended
use
as
a
fungicide
on
domestically
produced
fruiting
vegetables
(
except
cucurbits)
(
crop
group
8)
and
the
granting
of
the
requested
tolerances.

F.
International
Tolerances.

There
are
no
Canadian,
Mexican,
or
Codex
maximum
residue
levels
established
for
dimethomorph
for
the
commodities
associated
with
this
request;
consequently,
a
discussion
of
international
harmonization
is
not
relevant.
[
FR
Doc.
03
 
20899
Filed
8
 
19
 
03;
8:
45
am]

BILLING
CODE
6560
 
50
 
S
ENVIRONMENTAL
PROTECTION
AGENCY
[
OPP
 
2003
 
0222;
FRL
 
7316
 
3]

Issuance
of
Experimental
Use
Permits
AGENCY:
Environmental
Protection
Agency
(
EPA).
ACTION:
Notice.

SUMMMARY:
EPA
has
granted
experimental
use
permits
(
EUP)
to
the
following
pesticide
applicants.
An
EUP
permits
use
of
a
pesticide
for
experimental
or
research
purposes
only
in
accordance
with
the
limitations
in
the
permit.

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50144
Federal
Register
/
Vol.
68,
No.
161
/
Wednesday,
August
20,
2003
/
Notices
FOR
FURTHER
INFORMATION
CONTACT:
For
69592
 
EUP
 
1:
Susanne
Cerrelli,
Biopesticides
and
Pollution
Prevention
Division
(
7511C),
Office
of
Pesticide
Programs,
Environmental
Protection
Agency,
1200
Pennsylvania
Ave.,
NW.,
Washington,
DC
20460
 
0001;
telephone
number:
(
703)
308
 
8077;
e­
mail
address:
cerrelli.
susanne@
epa.
gov,
or
For
70515
 
EUP
 
3:
Carol
E.
Frazer,
Biopesticides
and
Pollution
Prevention
Division
(
7511C),
Office
of
Pesticide
Programs,
Environmental
Protection
Agency,
1200
Pennsylvania
Ave.,
NW.,
Washington,
DC
20460
 
0001;
telephone
number:
(
703)
308
 
8810;
e­
mail
address:
frazer.
carol@
epa.
gov.
SUPPLEMENTARY
INFORMATION:

I.
General
Information
A.
Does
this
Action
Apply
to
Me?

This
action
is
directed
to
the
public
in
general.
Although
this
action
may
be
of
particular
interest
to
those
persons
who
conduct
or
sponsor
research
on
pesticides,
the
Agency
has
not
attempted
to
describe
all
the
specific
entities
that
may
be
affected
by
this
action.
If
you
have
any
questions
regarding
the
information
in
this
action,
consult
the
persons
listed
under
FOR
FURTHER
INFORMATION
CONTACT.

B.
How
Can
I
Get
Copies
of
this
Document
and
Other
Related
Information?

1.
Docket.
EPA
has
established
an
official
public
docket
for
this
action
under
docket
identification
(
ID)
number
OPP
 
2003
 
0222.
The
official
public
docket
consists
of
the
documents
specifically
referenced
in
this
action,
any
public
comments
received,
and
other
information
related
to
this
action.
Although
a
part
of
the
official
docket,
the
public
docket
does
not
include
Confidential
Business
Information
(
CBI)
or
other
information
whose
disclosure
is
restricted
by
statute.
The
official
public
docket
is
the
collection
of
materials
that
is
available
for
public
viewing
at
the
Public
Information
and
Records
Integrity
Branch
(
PIRIB),
Rm.
119,
Crystal
Mall
#
2,
1921
Jefferson
Davis
Hwy.,
Arlington,
VA.
This
docket
facility
is
open
from
8:
30
a.
m.
to
4
p.
m.,
Monday
through
Friday,
excluding
legal
holidays.
The
docket
telephone
number
is
(
703)
305
 
5805.
2.
Electronic
access.
You
may
access
this
Federal
Register
document
electronically
through
the
EPA
Internet
under
the
``
Federal
Register''
listings
at
http://
www.
epa.
gov/
fedrgstr/.
An
electronic
version
of
the
public
docket
is
available
through
EPA's
electronic
public
docket
and
comment
system,
EPA
Dockets.
You
may
use
EPA
Dockets
at
http://
www.
epa.
gov/
edocket/
to
submit
or
view
public
comments,
access
the
index
listing
of
the
contents
of
the
official
public
docket,
and
to
access
those
documents
in
the
public
docket
that
are
available
electronically.
Although
not
all
docket
materials
may
be
available
electronically,
you
may
still
access
any
of
the
publicly
available
docket
materials
through
the
docket
facility
identified
in
Unit
I.
B.
1.
Once
in
the
system,
select
``
search,''
then
key
in
the
appropriate
docket
ID
number.

II.
EUP
EPA
has
issued
the
following
EUPs:
1.
69592
 
EUP
 
1.
Issuance.
AgraQuest,
Inc,
1530
Drew
Ave.,
Davis,
CA
95616.
This
EUP
allows
the
use
of
2,371.2
pounds
of
the
fungicide
Bacillus
pumilus
strain
QST2808
on
3,955
total
acres
of
brassica,
bulb
vegetables,
cereal
grains,
cucurbits,
fields
of
roses,
forestry,
fruiting
vegetables,
grapes,
grass
seed,
hops,
landscape,
leafy
vegetables,
legume
vegetables,
mint,
peanuts,
pome
fruits,
root/
tuber
vegetables,
stone
fruits,
strawberries,
and
sugarbeets
to
obtain
phytotoxicity
data
over
a
large
geographical
area
and
to
evaluate
the
control
of
various
plant
pathogens
including:
Bremia
lactucae,
Cercospora
spp.,
Erysiphe
spp.,
Oidiopsis
taurica,
Peronospora
parasitica,
Puccinia
spp.,
Sclerotinia
spp.,
Sphaerotheca
macularis,
Uncinula
necator,
Uromyces
phaseoli,
and
Phytophthora
spp.
The
program
is
authorized
only
in
the
States
of
Arizona,
California,
Colorado,
Georgia,
Florida,
Idaho,
Indiana,
Michigan,
Minnesota,
North
Carolina,
North
Dakota,
New
Jersey,
New
Mexico,
New
York,
Oklahoma,
Oregon,
Pennsylvania,
Texas,
Virginia,
Washington,
Wisconsin,
and
West
Virginia.
The
EUP
is
effective
from
June
6,
2003
to
June
30,
2005.
A
temporary
exemption
from
the
requirement
of
a
tolerance
for
residues
of
the
Bacillus
pumilus
strain
QST2808
in
or
on
all
agricultural
commodities
has
been
established.
2.
70515
 
EUP
 
3.
Issuance.
Nutra­
Park
Inc.,
3225
Deming
Way,
Suite
140,
Middleton,
WI
53562.
This
EUP
allows
the
use
of
220
gallons
of
the
growth
regulator
NPI
100
10EC
(
containing
the
active
ingredient
lysophosphatidylethanolamine
(
LPE))
on
5,000
acres
of
apples,
apricots,
avocados,
bananas,
blackberries,
blueberries,
boysenberries,
cherries,
coffee,
crabapples,
cranberries,
currants,
eggplant,
grapefruits,
grapes,
kiwis,
lemons,
limes,
mandarins,
mangos,
mineolas,
oranges,
peaches,
pears,
peppers,
pimentos,
pineapples,
plums,
pomegranates,
pummelos,
raspberries,
strawberries,
tangelos,
tangerines,
and
tomatoes
to
evaluate
the
control
of
ripening
and
shelf
life.
The
program
is
authorized
only
in
the
States
of
Arizona,
California,
Florida,
Georgia,
Massachusetts,
Oregon,
South
Carolina,
Washington,
and
Wisconsin.
The
EUP
is
effective
from
July
1,
2003
to
June
30,
2005.
An
exemption
from
the
requirement
of
a
tolerance
has
been
established
for
residues
of
the
active
ingredient
in
or
on
all
food
commodities.

Authority:
7
U.
S.
C.
136c.

List
of
Subjects
Environmental
protection,
Experimental
use
permits.

Dated:
August
8,
2003.
Janet
L.
Andersen,
Director,
Biopesticides
and
Pollution
Prevention
Division,
Office
of
Pesticide
Programs.
[
FR
Doc.
03
 
21353
Filed
8
 
19
 
03;
8:
45
am]

BILLING
CODE
6560
 
50
 
S 

ENVIRONMENTAL
PROTECTION
AGENCY
[
FRL
 
7546
 
6]

Proposed
Agreement
Pursuant
to
Sections
122(
g)
and
(
h)
of
the
Comprehensive
Environmental
Response,
Compensation,
and
Liability
Act
for
the
Chemical
Recovery
Systems
Superfund
Site
AGENCY:
Environmental
Protection
Agency
(``
EPA'').
ACTION:
Notice;
request
for
public
comment
on
proposed
de
minimis
settlement.

SUMMARY:
In
accordance
with
Section
122(
i)
of
the
Comprehensive
Environmental
Response,
Compensation,
and
Liability
Act,
as
amended
(``
CERCLA''),
42
U.
S.
C.
9622(
i),
notice
is
hereby
given
of
a
proposed
administrative
settlement
for
recovery
of
response
costs
concerning
the
Chemical
Recovery
Systems
Superfund
Site
in
Elyria,
Ohio.
EPA
proposes
to
enter
into
this
agreement
under
the
authority
of
sections
122(
g)
and
(
h)
and
107
of
CERCLA.
In
addition
to
the
review
by
the
public
pursuant
to
this
document,
the
agreement
has
been
approved
by
the
United
States
Department
of
Justice.
The
proposed
agreement
has
been
executed
by
the
following
eighty
three
(
83)
de
minimis
parties:
3M
Company
Adelphia,
Inc.
Aexcel
Corporation
(
f/
k/
a
DeSantis
Coatings)

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