Document ID: EPA-HQ-ORD-2007-1083-0005
Agency: epa
Document Type: Notice
Title: Draft Toxicological Review of 1,2,3-Trichloropropane: In Support of the Summary Information in the Integrated Risk Information System (IRIS)
Posted Date: 2008-01-18T05:00Z

[Federal Register: January 18, 2008 (Volume 73, Number 13)]
[Notices]               
[Page 3462-3463]
From the Federal Register Online via GPO Access [wais.access.gpo.gov]
[DOCID:fr18ja08-49]                         

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ENVIRONMENTAL PROTECTION AGENCY

[FRL-8517-8; Docket ID No. EPA-HQ-ORD-2007-1083]

 
Draft Toxicological Review of 1,2,3-Trichloropropane: In Support 
of the Summary Information in the Integrated Risk Information System 
(IRIS)

AGENCY: Environmental Protection Agency (EPA).

ACTION: Notice.

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SUMMARY: EPA is announcing that Versar, Inc., an EPA contractor for 
external scientific peer review, will convene an independent panel of 
experts and organize and conduct an external peer-review meeting to 
review the external review draft document titled, ``Toxicological 
Review of 1,2,3-Trichloropropane: In Support of Summary Information on 
the Integrated Risk Information System (IRIS)'' (NCEA-S-1669). EPA 
previously announced the 60-day public comment period (ending January 
15, 2008) for the draft document in the Federal Register on November 
16, 2007 (72 FR 64626). EPA will consider public comments and 
recommendations from the expert panel meeting as EPA finalizes the 
draft document.
    The public comment period and the external peer-review meeting are 
separate processes that provide opportunities for all interested 
parties to comment on the document. EPA intends to forward public 
comments submitted in accordance with Federal Register (72 FR 64626) to 
Versar, Inc., for consideration by the external peer-review panel prior 
to the meeting.
    EPA is releasing this draft document solely for the purpose of pre-
dissemination peer review under applicable information quality 
guidelines. This document has not been formally disseminated by EPA. It 
does not represent and should not be construed to represent any Agency 
policy or determination.
    Versar, Inc., invites the public to register to attend this meeting 
as observers. In addition, Versar, Inc., invites the public to give 
brief oral comments at the meeting regarding the draft document under 
review. The draft document and EPA's peer-review charge are available 
via the Internet on NCEA's home page under the Recent Additions and the 
Data and Publications menus at http://www.epa.gov/ncea. When finalizing 

the draft document, EPA intends to consider Versar's report of the 
comments and recommendations from the external peer-review meeting and 
any public comments that EPA receives in accordance with 72 FR 64626, 
November 16, 2007. Public comments that were submitted during the 60-
day public comment period ending January 15, 2008 may be observed at 
http://www.regulations.gov under Docket ID No. EPA-HQ-ORD-2007-1083.

DATES: The peer-review panel meeting will begin on February 20, 2008, 
at 8:30 a.m. and end at 5 p.m. Register by February 15, 2008, if you 
wish to provide brief oral comments at the meeting.

ADDRESSES: The peer-review meeting will be held at the Hyatt Regency 
Crystal City, 2799 Jefferson Davis Highway, Arlington, VA 22202. 
Versar, Inc., is organizing, convening, and conducting the peer-review 
meeting. To attend the meeting, register by February 15, 2008, via the 
Internet at http://epa.versar.com/123TCP/.

    The draft ``Toxicological Review of 1,2,3-Trichloropropane: In 
Support of Summary Information on the Integrated Risk Information 
System (IRIS)'' is available via the Internet on the National Center 
for Environmental Assessment's (NCEA) home page under the Recent 
Additions and the Data and Publications menus at http://www.epa.gov/ncea.
 A limited number of paper copies are available from the 

Information Management Staff, NCEA; telephone: 703-347-8561; facsimile: 
703-347-8691. If you are requesting a paper copy, please provide your 
name, mailing address, and the document title. Copies are not available 
from Versar, Inc.

FOR FURTHER INFORMATION CONTACT: For information on the peer review 
meeting, contact Stephanie Sarraino, Versar, Inc.; telephone: 703-750-
3000 ext. 316; e-mail: ssarraino@versar.com.
    If you have questions about the document, contact Martin Gehlhaus, 
IRIS Staff, National Center for Environmental Assessment, (8601P), U.S. 
EPA, 1200 Pennsylvania Avenue, NW., Washington, DC 20460; telephone: 
703-347-8579; facsimile: 713-347-8689; e-mail: gehlhaus.martin@epa.gov.

SUPPLEMENTARY INFORMATION:

I. Summary of Information About the Integrated Risk Information System 
(IRIS)

    IRIS is a database that contains potential adverse human health 
effects information that may result from chronic (or lifetime) exposure 
to specific chemical substances found in the environment. The database 
(available on the Internet at http://www.epa.gov/iris) contains 

qualitative and quantitative health effects information for more than 
500 chemical substances that may be used to support the first two steps 
(hazard identification and dose-response evaluation) of a risk 
assessment process. When supported by available data, the database 
provides oral reference doses (RfDs) and inhalation reference 
concentrations (RfCs) for chronic health effects, and oral slope 
factors and inhalation unit risks for carcinogenic effects. Combined 
with specific exposure information, government and private entities can 
use IRIS data to help characterize public health risks of chemical 
substances in a site-specific situation and thereby support risk 
management decisions designed to protect public health.

[[Page 3463]]

II. Meeting Information

    Members of the public may attend the meeting as observers, and 
there will be a limited time for oral comments from the public. Please 
let Versar, Inc. know if you wish to make comments during the meeting 
by registering on the Web site at http://epa.versar.com/123TCP/ and 

indicating your intent to make oral comments. Space is limited, and 
reservations will be accepted on a first-come, first-served basis.

    Dated: January 11, 2008.
Rebecca Clark,
Acting Director, National Center for Environmental Assessment.
 [FR Doc. E8-887 Filed 1-17-08; 8:45 am]

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