Document ID: FDA-2002-N-0031-0123
Agency: fda
Document Type: Supporting & Related Material
Title: 
Posted Date: 2008-04-25T04:00Z

<!DOCTYPE HTML PUBLIC "-//-//W3C//DTD HTML 3.2//EN">
<HTML>
<HEAD>
<META name="generator" content="PDFCreactiveX HTML Export">
<META name="creation-date" content="24/04/2008 07:01:02 ">
<TITLE></TITLE>
<SCRIPT LANGUAGE="JavaScript1.2"> var agt=navigator.userAgent.toLowerCase();if ( (parseInt(navigator.appVersion)>=4) &&(agt.indexOf('mozilla')!=-1) && (agt.indexOf('spoofer')==-1)&& (agt.indexOf('compatible') == -1) ){msie = false;} else if ( (parseInt(navigator.appVersion)>=4) &&(agt.indexOf('msie') != -1) ) {msie = true;	} page=0;</SCRIPT>
</HEAD>
<BODY bgcolor="#ffffff" text="#000000" topmargin=0 leftmargin=0 marginheight=0 marginwidth=0 >
<SPAN STYLE="color:#000000;background-color:#ffffff;position:absolute;left:0.00pt;top:-1.00pt;z-index:2;"><IMG WIDTH=1696 HEIGHT=2200 style="width:610pt;height:792pt;" SRC="outputfile270663856.htm_files\outputfile270663856_p0.png"></SPAN>
<SPAN STYLE="position:absolute;left:71.76pt;top:792.00pt"> </SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:49.45pt;top:808.55pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:103.55pt;top:808.60pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:109.90pt;top:808.75pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:239.40pt;top:808.60pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:246.10pt;top:808.75pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:271.30pt;top:808.60pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:278.30pt;top:808.75pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:324.00pt;top:805.95pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:331.20pt;top:808.55pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:495.00pt;top:808.75pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:58.70pt;top:939.35pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:59.65pt;top:974.45pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:158.40pt;top:967.15pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:166.45pt;top:976.20pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:294.00pt;top:974.45pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:325.20pt;top:976.20pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:340.10pt;top:974.45pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:364.30pt;top:976.20pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:58.70pt;top:990.95pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:58.90pt;top:1019.00pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:58.70pt;top:1044.65pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:192.95pt;top:1074.90pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:251.40pt;top:1075.25pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:282.85pt;top:1074.90pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:363.35pt;top:1074.90pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:190.55pt;top:1095.70pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:254.85pt;top:1095.70pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:311.65pt;top:1095.70pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:366.25pt;top:1095.45pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:190.55pt;top:1123.55pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:254.15pt;top:1123.30pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:311.65pt;top:1123.30pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:365.55pt;top:1123.05pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:190.55pt;top:1151.00pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:254.15pt;top:1151.00pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:311.65pt;top:1150.85pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:365.50pt;top:1150.80pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:190.55pt;top:1179.35pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:252.00pt;top:1179.35pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:312.10pt;top:1179.10pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:363.60pt;top:1178.85pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:190.55pt;top:1207.20pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:254.15pt;top:1206.95pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:311.65pt;top:1206.80pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:365.50pt;top:1206.70pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:190.55pt;top:1234.40pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:250.70pt;top:1234.40pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:311.40pt;top:1234.40pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:362.40pt;top:1234.20pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:190.55pt;top:1262.25pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:249.00pt;top:1262.25pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:311.40pt;top:1262.25pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:360.00pt;top:1262.10pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:365.50pt;top:1262.00pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:190.10pt;top:1485.70pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:242.30pt;top:1485.70pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:305.30pt;top:1485.70pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:353.65pt;top:1485.70pt;z-index:3;"></SPAN>
<SPAN STYLE="position:absolute;left:71.76pt;top:1584.00pt"> </SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:54.25pt;top:1597.50pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:108.00pt;top:1598.00pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:114.70pt;top:1597.70pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:244.10pt;top:1595.40pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:250.55pt;top:1597.70pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:275.75pt;top:1598.00pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:282.70pt;top:1597.70pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:328.30pt;top:1595.40pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:335.30pt;top:1597.50pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:498.95pt;top:1598.40pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:195.35pt;top:1654.80pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:195.35pt;top:1682.65pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:195.10pt;top:1710.45pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:195.10pt;top:1738.55pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:194.90pt;top:1766.15pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:195.10pt;top:1794.45pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:194.90pt;top:1822.80pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:194.65pt;top:1850.65pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:194.65pt;top:1878.00pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:194.65pt;top:1906.05pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:194.65pt;top:1933.90pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:193.70pt;top:1961.50pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:193.45pt;top:1989.10pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:193.45pt;top:2016.70pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:184.30pt;top:2044.70pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:174.50pt;top:2072.05pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:62.65pt;top:2130.95pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:82.30pt;top:2131.65pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:128.90pt;top:2131.60pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:139.45pt;top:2131.65pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:164.15pt;top:2131.60pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:248.40pt;top:1654.80pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:250.30pt;top:1682.65pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:250.10pt;top:1710.70pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:250.10pt;top:1738.80pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:250.10pt;top:1766.40pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:249.85pt;top:1794.45pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:250.55pt;top:1822.55pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:255.35pt;top:1850.40pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:254.90pt;top:1878.25pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:254.90pt;top:1906.05pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:254.90pt;top:1934.15pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:257.50pt;top:1961.25pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:257.50pt;top:1989.10pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:258.00pt;top:2016.95pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:246.00pt;top:2044.80pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:244.05pt;top:2071.90pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:311.25pt;top:1654.80pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:313.45pt;top:1682.85pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:313.20pt;top:1710.95pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:312.70pt;top:1738.80pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:313.20pt;top:1766.40pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:311.05pt;top:1794.70pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:310.80pt;top:1822.80pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:312.50pt;top:1850.40pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:315.35pt;top:1878.25pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:315.10pt;top:1906.05pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:314.90pt;top:1933.90pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:314.90pt;top:1961.50pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:314.65pt;top:1989.35pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:314.65pt;top:2017.20pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:315.35pt;top:2044.80pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:306.00pt;top:2071.90pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:359.55pt;top:1654.80pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:361.90pt;top:1682.65pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:361.45pt;top:1710.70pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:361.45pt;top:1738.80pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:361.45pt;top:1766.65pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:361.45pt;top:1794.70pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:361.90pt;top:1822.55pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:364.55pt;top:1850.40pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:366.70pt;top:1878.25pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:366.25pt;top:1906.05pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:366.25pt;top:1934.15pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:369.10pt;top:1961.75pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:368.65pt;top:1989.10pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:368.65pt;top:2016.95pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:357.60pt;top:2045.05pt;z-index:3;"></SPAN>
<SPAN STYLE="color:#000000;position:absolute;left:355.45pt;top:2071.90pt;z-index:3;"></SPAN>
<SPAN STYLE="position:absolute;left:71.76pt;top:2374.00pt"> </SPAN>
</BODY>
</HTML>