Document ID: EPA-HQ-ORD-2014-0564-0002
Agency: epa
Document Type: Supporting & Related Material
Title: 
Posted Date: 2014-08-15T04:00Z

UNITED STATES ENVIRONMENTAL PROTECTION AGENCY
                       HUMAN STUDIES REVIEW BOARD (HSRB)
                         PUBLIC TELECONFERENCE/WEBINAR
                                 MEETING AGENDA
                                       
                            Friday, August 15, 2014
                       2:00 pm - 3:00 pm (Eastern Time)*
                                       
                  HSRB MEETING FOR REVIEW AND APPROVAL OF THE
                    JUNE 11, 2014 HSRB MEETING FINAL REPORT
                                       
                  HSRB WEB SITE http://www.epa.gov/osa/hsrb/
                       Docket Telephone: (202) 566 1752
                   Docket Number: EPA - HQ - ORD - 2014-0564
                                       
                 Meeting location via telephone/Internet only
           Dial in number 866-299-3188; conference code 2025647189 
                   https://epa.connectsolutions.com/hsrbtele
                                       
2:00 PM	Convene Meeting and Identification of Board Members  -  Jim Downing (Designated Federal Officer, EPA HSRB, OSA)
2:05 PM*	Meeting Administrative Procedures  -  Jim Downing, DFO
2:10 PM	Meeting Process  -  Rebecca Parkin, Ph.D., MPH (HSRB Chair)
2:15 PM	Public Comments
2:20 PM	Board Discussion and Decision on Final Report  - Rebecca Parkin, Ph.D., MPH (HSRB Chair)

The Board's response to EPA charge questions presented at the June 11, 2014 meeting.

A published report by Paul et al (1988) of an intentional exposure human study measuring the effects of small increases of dietary iodine on thyroid function.

Charge to the Board - Science

   * Is this study scientifically sound, providing reliable data?
   * If so, is this study relevant for quantitative use in support of an assessment of the oral risk of exposure to iodine?

Charge to the Board - Ethics

   * Does the study meet the applicable requirements of 40 CFR part 26 subpart Q?

A published report by Gardner et al (1988) of an intentional exposure human study measuring the effects of low dose oral iodide supplementation on thyroid function.

Charge to the Board - Science

   * Is this study scientifically sound, providing reliable data?
   * If so, is this study relevant for quantitative use in support of an assessment of the oral risk of exposure to iodine?

Charge to the Board - Ethics

   * Does the study meet the applicable requirements of 40 CFR part 26 subpart Q?

A published report by Lemar et al (1995) of an intentional exposure human study measuring the effects of chronic tetraglycine hydroperiodide water purification tablet use on thyroid function.

Charge to the Board - Science

   * Is this study scientifically sound, providing reliable data?
   * If so, is this study relevant to establish the reversibility of high dose iodine exposure?
   * Also, is this study sufficient to establish that there are no sustained adverse effects from high dose iodine exposure?

Charge to the Board - Ethics

   * Does the study meet the applicable requirements of 40 CFR part 26 subpart Q?
           
2:45 PM*	HSRB Work Group on Return of Individual Research Results Report

2:55 PM*	Summary and Next Steps  -  Rebecca Parkin, Ph.D., MPH (HSRB Chair) and Jim Downing (DFO)

3:00 PM* 	Adjournment