Document ID: EPA-HQ-ORD-2008-0165-0001
Agency: epa
Document Type: Notice
Title: Draft Toxicological Review of Propionaldehyde: In Support of Summary Information on the Integrated Risk Information System (IRIS)
Posted Date: 2008-03-06T05:00Z

[Federal Register: March 6, 2008 (Volume 73, Number 45)]
[Notices]               
[Page 12171-12172]
From the Federal Register Online via GPO Access [wais.access.gpo.gov]
[DOCID:fr06mr08-61]                         

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ENVIRONMENTAL PROTECTION AGENCY

[FRL-8538-4; Docket ID No. EPA-HQ-ORD-2008-0165]

 
Draft Toxicological Review of Propionaldehyde: In Support of 
Summary Information on the Integrated Risk Information System (IRIS)

AGENCY: Environmental Protection Agency (EPA).

ACTION: Notice of public comment period.

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SUMMARY: The EPA is announcing a public comment period to review 
selected sections of the final draft document titled, ``Toxicological 
Review of Propionaldehyde: In Support of Summary Information on the 
Integrated Risk Information System (IRIS)'' (EPA/600/R-08/003), related 
to the human health assessment for Propionaldehyde. The document was 
prepared by the National Center for Environmental Assessment (NCEA) 
within EPA's Office of Research and Development.
    Public comments submitted to the EPA by May 5, 2008 will be 
provided to the external peer review panel prior to their meeting (to 
be announced).
    EPA is releasing the draft document solely for the purpose of pre-
dissemination peer review under applicable information quality 
guidelines. This document has not been formally disseminated by EPA. It 
does not represent and should not be construed to represent any Agency 
policy or determination. EPA will consider any public comments 
submitted in accordance with this notice when revising the document.

DATES: The 60-day public comment period begins on March 6, 2008 and 
ends May 5, 2008. Technical comments should be in writing and must be 
received by EPA by May 5, 2008. The peer review panel meeting will be 
announced in a subsequent Federal Register Notice.

ADDRESSES: The draft ``Toxicological Review of Propionaldehyde: In 
Support of Summary Information on the Integrated Risk Information 
System (IRIS)'' (EPA/600/R-08/003) is available primarily via the 
Internet on NCEA's

[[Page 12172]]

home page under the Recent Additions menu at http://www.epa.gov/ncea. A 
limited number of paper copies are available by contacting the IRIS 
Hotline at (202) 566-1676, (202) 566-1749 (facsimile), or 
hotline.iris@epa.gov. If you are requesting a paper copy, please 
provide your name, mailing address, the document title, and the EPA 
number of the requested publication. Technical comments may be 
submitted electronically via www.regulations.gov, by mail, by 
facsimile, or by hand delivery/courier. Please follow the detailed 
instructions provided in the SUPPLEMENTARY INFORMATION section of this 
notice.

FOR FURTHER INFORMATION CONTACT: For information on the public comment 
period, contact the Office of Environmental Information Docket; 
telephone: 202-566-1752; facsimile: 202-566-1753; or e-mail: 
ORD.Docket@epa.gov.
    If you have questions about the document, contact John Stanek, 
Chemical Manager, National Center for Environmental Assessment; 
telephone: 919-541-1048; facsimile: 919-541-0248; e-mail: 
stanek.john@epa.gov.

SUPPLEMENTARY INFORMATION:

I. Information About the Document

    IRIS is a database that contains scientific Agency positions on 
potential adverse human health effects that may result from chronic (or 
lifetime) exposure to specific chemical substances found in the 
environment. The database (available on the Internet at http://
www.epa.gov/iris) contains qualitative and quantitative health effects 
information for more than 500 chemical substances that may be used to 
support the first two steps (hazard identification and dose-response 
evaluation) of the risk assessment process. When supported by available 
data, the database provides oral reference doses (RfDs) and inhalation 
reference concentrations (RfCs) for chronic health effects, and oral 
slope factors and inhalation unit risks for carcinogenic effects. 
Combined with specific exposure information, government and private 
entities use IRIS to help characterize public health risks of chemical 
substances in a site-specific situation and thereby support risk 
management decisions designed to protect public health.

II. How To Submit Technical Comments to the Docket at 
www.regulations.gov

    Submit your comments, identified by Docket ID No. EPA-HQ-ORD-2008-
0165, by one of the following methods:
     www.regulations.gov: Follow the on-line instructions for 
submitting comments.
     E-mail: ORD.Docket@epa.gov.
     Fax: 202-566-1753.
     Mail: Office of Environmental Information (OEI) Docket 
(Mail Code: 2822T), U.S. Environmental Protection Agency, 1200 
Pennsylvania Ave., NW., Washington, DC 20460. The phone number is 202-
566-1752.
     Hand Delivery: The OEI Docket is located in the EPA 
Headquarters Docket Center, Room 3334 EPA West Building, 1301 
Constitution Ave., NW., Washington, DC. The EPA Docket Center Public 
Reading Room is open from 8:30 a.m. to 4:30 p.m., Monday through 
Friday, excluding legal holidays. The telephone number for the Public 
Reading Room is 202-566-1744. Such deliveries are only accepted during 
the docket's normal hours of operation, and special arrangements should 
be made for deliveries of boxed information.
    If you provide comments by mail or hand delivery, please submit 
three copies of the comments. For attachments, provide an index, number 
pages consecutively with the comments, and submit an unbound original 
and three copies.
    Instructions: Direct your comments to Docket ID No. EPA-HQ-ORD-
2008-0165. Please ensure that your comments are submitted within the 
specified comment period. Comments received after the closing date will 
be marked ``late,'' and may only be considered if time permits. It is 
EPA's policy to include all comments it receives in the public docket 
without change and to make the comments available online at 
www.regulations.gov, including any personal information provided, 
unless a comment includes information claimed to be Confidential 
Business Information (CBI) or other information whose disclosure is 
restricted by statute. Do not submit information that you consider to 
be CBI or otherwise protected through www.regulations.gov or e-mail. 
The www.regulations.gov Web site is an ``anonymous access'' system, 
which means EPA will not know your identity or contact information 
unless you provide it in the body of your comment. If you send an e-
mail comment directly to EPA without going through www.regulations.gov, 
your e-mail address will be automatically captured and included as part 
of the comment that is placed in the public docket and made available 
on the Internet. If you submit an electronic comment, EPA recommends 
that you include your name and other contact information in the body of 
your comment and with any disk or CD-ROM you submit. If EPA cannot read 
your comment due to technical difficulties and cannot contact you for 
clarification, EPA may not be able to consider your comment. Electronic 
files should avoid the use of special characters, any form of 
encryption, and be free of any defects or viruses. For additional 
information about EPA's public docket visit the EPA Docket Center 
homepage at http://www.epa.gov/epahome/dockets.htm.
    Docket: Documents in the docket are listed in the 
www.regulations.gov index. Although listed in the index, some 
information is not publicly available, e.g., CBI or other information 
whose disclosure is restricted by statute. Certain other materials, 
such as copyrighted material, are publicly available only in hard copy. 
Publicly available docket materials are available either electronically 
in www.regulations.gov or in hard copy at the OEI Docket in the EPA 
Headquarters Docket Center.

    Dated: February 28, 2008.
Rebecca Clark,
Deputy Director, National Center for Environmental Assessment.
[FR Doc. E8-4358 Filed 3-5-08; 8:45 am]

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