Document ID: EPA-HQ-OPPT-2002-0025-0036
Agency: epa
Document Type: Supporting & Related Material
Title: 
Posted Date: 2002-10-18T04:00Z

What's
New?

How
much
is
the
PBT
Profiler
being
used?
The
PBT
Profiler
now
counts
user
"hits"
on
the
Home
Page
andthe
numberofprofiles
run.
Details.

Known
Issues
(bugs
or
other
problems)

 
None
Version
History
4/
12/
2001
Version
0.
911
 
Methodology
section
expanded
 
Text
on
numerous
pages
updated
to
reflect
newest
version
 
Routines
to
URL
encode
SMILES
string
for
structure
display
added
 
Bug
that
shows
B&
W/
color
switch
during
metal
flag
fixxed
 
Routines
to
add
brackets
to
the
SMILES
string
of
Na
and
K
salts
added
so
that
userentered
salts
display
properly
added
10/
11/
2000
Version
0.
910
 
Method
to
determine
persistence
updated.
The
persistence
ranking
was
modified
to
compare
the
half­
life
in
the
medium
(environmental
compartment)
a
chemical
was
most
likely
to
be
found
in
(water,
soil
or
sediment)
to
the
PBT
Profiler
criteria.
The
mult
ipliers
used
to
determine
the
half­
life
in
soil
and
sediment
(relative
to
that
estimated
in
water
by
the
ultimate
survey
model
)
were
updated.
 
Results
page
reformatted.
 
Characteristic
Travel
Distance
(CTD)
added
to
Results
page.
 
Overall
persistence
from
fugacity
model
added
to
Results
page.
 
Picture
of
the
user­
entered
chemical
structure
added
to
Data
Entry
and
Results
page.
 
Routines
to
view
a
structure
based
on
a
user­
entered
SMILES
(before
the
chemical
is
added
to
the
list)
added.
 
Black­
and­
white
version
of
the
Data
Entry
and
Results
pages
added;
descriptions
and
format
added
to
Definitions
and
Interpreting
the
PBT
Profiler
Results
pages.
 
The
P2
Considerations
page
was
expanded
and
reformatted.
This
page
now
includes
a
discussion
of
the
CTD,
provides
information
on
different
release
scenarios,
and
contains
separate
partitioning
and
transport
sections.
 
Bug
that
didn't
transfer
user­
entered
CAS
from
drawing
program
fixed.
 
Methodology,
Definition,
and
Interpreting
the
PBT
Profiler
Results
pages
expanded
to
include
a
discussion
of
changes
and
additions
identified
here.
 
Routines
to
identify
common
inorganic
chemicals
in
the
lookup
database
(and
preventthem
from
beingrunin
the
Profiler)
were
added.
 
Discussion
of
chemical
classes
that
should
not
be
profiled
was
expanded
to
include
surfactants.
 
Discussion
of
how
the
PBT
Profiler
does
not
explicitly
consider
groundwater
expanded
on
the
P2
Considerations
and
Methodology
pages.

4/
25/
2000
Version
0.
902
 
Methodology
and
criteria
sections
expanded
and
rewritten.
 
A
multiple­
chemical
profile
bug
that
caused
the
no
effects
at
saturation
flag
to
be
displayed
incorrectly
was
fixed.

3/
27/
2000
Version
0.
901
 
Routines
added
to
count
the
number
of
"hits"
onthe
Home
Page
andthe
number
of
profiles
run.
Users
can
view
how
often
the
PBT
Profiler
is
used
and
the
computer
code
used
to
collect
this
information.
 
Results
page
routines
expanded
to
keep
the
PBT
Profiler
working
when
the
estimation
methods
give
erratic
results.
 
Discussions
why
the
persistence,
bioaccumulation,
or
toxicity
can
not
be
estimated
were
expanded
(P2
considerations).
 
Bug
in
displaying
the
colored
arrows
fixed
(Data
Entry)
 
Fix
for
updating
chemical
name
added
(Data
Entry)

3/
08/
2000
Estimation
routines
and
chemical
details
page
updated
to
identify
chemicals
that
exceed
the
log
octanol/
water
partition
coefficient
cutoff
for
the
aquatic
toxicit
y
SARs.

3/
06/
2000
Version
0.
900
released
for
testing
This
version
incorporates
suggestions
from
the
Betatesters
as
wellas
othersignificant
enhancements:

 
Website
redesigned
to
facilitate
navigation
between
all
pages
and
keep
the
current
profile
active
 
Pollution
Prevention
Considerations
page
added
to
add
chemical­
specific
perspective
to
the
PBT
Profiler
results.
This
discussion
considers
both
a
chemical's
half­
life
and
the
environmental
compartment
it
is
found
in
to
identify
P2
opportunit
ies
 
Home
Page
redesigned
and
informational
pages
including
a
how
to
use
the
PBT
Profiler,
how
to
interpret
the
results,
and
information
needed
added
 
Data
Entry
screen
redesigned
and
reprogrammed
to
guide
the
user
through
the
process
 
Overall
Persistence
(from
the
fugacity
model)
removed
from
the
results
page
as
this
value
provided
a
relative,
not
an
absolute,
persistence
 
Chemical
drawing
interface
(experimental)
added
to
facilitatestructure
entry
 
Notes
on
how
the
PBT
Profiler
uses
data
entered
 
Data
Entry
Help
expanded
to
provide
information
on
thelookupfunction,
SMILES
notations,
and
ID
numbers
 
Example
chemical
page
added
to
help
users
familiarize
themselves
with
the
PBT
Profiler
 
Methodology
page
expanded
to
include
validation
section
 
Algorithm
for
identifying
metals
in
userentered
SMILES
added
to
data
entry
page
 
PBT
Profiler
completely
reprogrammed
to
remove
the
java­
based
object
oriented
scripting
language
that
was
not
functioning
correctly
on
some
local
area
networks.
 
Routines
for
flagging
known
PBTs
at
data
entry
added
11/
1/
99
The
first
developmental
version
of
the
PBT
Profiler,
Version
0.88,
Released
for
Beta
Testing
to
volunteers
in
academics,
industry,
and
government.
Beta
test
coordinated
by
Ihab
H.
Farag,
Sc.
D.,
P.
E.,
Robert
C.
Davison
Professor,
University
of
New
Hampshire.
Director,
The
New
Hampshire
Pollut
ion
Prevention
Partnership
Developed
by
the
Environmental
Science
Center
under
contract
to
the
Office
of
Pollution
Prevention
and
Toxics
,
U.
S.
Environmental
Protection
Agency
Computer
Resources
Donated
by
Syracuse
Research
Corporation
Ver
0.
911
BetaR
Restricted
Access
Last
Updated
April
18,
2001