Document ID: EPA-HQ-OPP-2007-0337-0012
Agency: epa
Document Type: Supporting & Related Material
Title: 
Posted Date: 2008-09-24T04:00Z

UNITED STATES ENVIRONMENTAL PROTECTION AGENCY

WASHINGTON, D.C.  20460

OFFICE OF           

PREVENTION, PESTICIDES

AND TOXIC SUBSTANCES

MEMORANDUM

	Date:	2/27/2008

	Subject:	Addendum to:  D331951, Cyfluthrin/Beta-cyfluthrin – Human
Health Risk Assessment For New Uses on Grasses, Alfalfa, and Sugar Beet
Seed and Revised Tolerances on Cereal Grain Commodities; and D339413,
Cyfluthrin and beta-Cyfluthrin,  Summary of Analytical Chemistry and
Residue Data.  

Petition Nos.	6E7058 (Grasses)

6F7160 (Sugar Beets)

7F7226 (Alfalfa)

7F7200 (Cereal Grains and Forage, Fodder, and Hay of Cereal Grains)

DP Number:	D349871

PC Codes:	128831 - Cyfluthrin 

118831 - Beta Cyfluthrin

40 CFR 180.	436

Chemical Class:	Pyrethroid

	From:	Douglas Dotson, Ph.D., Chemist

		Registration Action Branch 2

		Health Effects Division (7509P)

	Through:	Michael Doherty, Ph.D., Senior Scientist

		Registration Action Branch 2

		Health Effects Division (7509P)

	To:	Olga Odiott/George LaRocca, RM Team 13

		Insecticide Branch

		Registration Division (7505P)

The purpose of this memorandum is to inform the Registration Division
that HED recommends in favor of the establishment of tolerances for
cyfluthrin and beta-cyfluthrin on the commodities popcorn and teosinte. 
HED recently completed a human health risk assessment for cyfluthrin and
beta-cyfluthrin (Memo, D331951, C. Swartz, et al., 10/23/2007).  In
support of this risk assessment, HED also prepared a residue chemistry
summary document (Memo, D339413, D. Dotson, 10/15/2007).  In both of
these documents, HED recommended in favor of the establishment of
tolerances for cereal grain commodities.  The commodities popcorn,
grain, and

 

teosinte, grain, were inadvertently left off of the list of commodities
for which HED was recommending tolerances.  These commodities should
have been included on the list.

Popcorn grain was included in the dietary exposure analysis (Memo,
D339414, D. Dotson, 8/31/2007) performed in support of the risk
assessment.  Therefore, the dietary exposure and risk estimates that
were reported in the cited risk assessment do not change as a result of
the addition of popcorn to the list of commodities with recommended
tolerances.  HED recommended in favor of a tolerance of 0.05 ppm for
field corn grain in order to harmonize with the Codex MRL.  HED is now
recommending in favor of a tolerance of 0.05 ppm for corn, pop, grain. 
The dietary exposure and risk estimates are given in both the dietary
exposure memo and risk assessment cited above.

Teosinte was not included in the dietary exposure analysis performed for
the risk assessment.  However, there is no entry in the dietary exposure
model, DEEM-FCID for teosinte.  DEEM-FCID utilizes food consumption data
from the Continuing Surveys of Food Intakes by Individuals.  There is no
entry in the dietary model for teosinte, which means that no one who
participated in the food consumption survey reported eating teosinte. 
In addition, teosinte is not a significant animal feed item.  Therefore,
animal commodity tolerances do not change as a result of the addition of
teosinte to the list of commodities with cyfluthrin tolerances.  As a
result, the dietary exposure and risk estimates that were reported in
the cited risk assessment do not change. The recommended tolerance for
teosinte, grain is the same as that for wheat grain:  0.15 ppm.

Table 1 provides the proposed and recommended tolerances associated with
tolerance petition 7F7200.  This list is the same as the list provided
in the previous residue chemistry summary document except that it
includes popcorn, grain and teosinte, grain.  The previous table also
contained four typographical errors that are corrected in the table
below.  In the previous table, the correct commodity definition for the
forage, stover, straw, and hay of the cereal grains crop group
erroneously stated that these commodities were in Crop Group 17.  These
commodities actually make up Crop Group 16.  As stated above, this error
is corrected in the table below.

Table 1.  Tolerance Summary for Cyfluthrin and beta-Cyfluthrin

Commodity	Established Tolerance

(ppm)	Proposed Tolerance

(ppm)	Recommended Tolerance

(ppm)	Comments, Correct Commodity Definition

Grass, forage, fodder and hay, group 17, forage	6.0 1	13.0	12	Adequate
grass field trial data are available.

Grass, forage, fodder and hay, group 17, hay	8.0 1	40.0	50

	Alfalfa, forage	-	5.0	5.0	Adequate alfalfa field trial data are
available.

Alfalfa, hay	10.0	15.0	13

	Beet, sugar, roots	-	0.09	0.10	Adequate field trial data are available

Beet, sugar, dried pulp	-	11	1.0	Maximum expected residues are 0.59 ppm
based on HAFT residues of 0.049 ppm and a 12x processing factor for
dried pulp.

Grain, cereal; Crop Group 15 (except Rice)	4.0	4.0	0.15	Wheat grain,
barley grain, buckwheat grain, millet grain, oat grain, rye grain,
teosinte, grain.

Grain, cereal; Crop Group 15 (except Rice)	4.0	4.0	0.05	Corn, field,
grain and corn, pop, grain

Grain, cereal; Crop Group 15 (except Rice)	4.0	4.0	0.05	Corn, sweet,
kernel plus cob with husks removed

Grain, cereal; Crop Group 15 (except Rice)	4.0	4.0	3.5	Sorghum, grain,
grain

Wheat, bran	6.5	-	0.5	Stored grain uses have been revoked. A tolerance
of 0.15 ppm is being recommended for wheat grain.

Corn, field, refined oil	30.0	-	-	The field corn, grain tolerance will
cover residues in corn oil

Rice, bran	6.0	-	-	Stored grain uses have been revoked

Rice, hulls	18.0	-	-	Stored grain uses have been revoked

Grain, cereal, forage, fodder and straw, Crop Group 16 (except Rice)	-2
7.0	25	Grain, cereal, forage, fodder, and hay, group 16, forage, except
Rice

Grain, cereal, forage, fodder and straw, Crop Group 16 (except Rice)	- 3
7.0	30	Grain, cereal, forage, fodder, and hay, group 16, stover, except
Rice

Grain, cereal, forage, fodder and straw, Crop Group 16 (except Rice)	- 4
7.0	7.0	Grain, cereal, forage, fodder, and hay, group 16, straw, except
Rice

Grain, cereal, forage, fodder and straw, Crop Group 16 (except Rice)	- 5
7.0	6.0	Grain, cereal, forage, fodder, and hay, group 16, hay, except
Rice

Wheat, forage	5.0	-	-	Crop group tolerance is being established for
Forage of Grain, Cereal, except Rice (Crop Group 16)

Corn, field, forage	3.0	-	-

	Corn, sweet, forage	15	-	-

	Sorghum, grain, forage	2.0	-	-

	Corn, field, stover	6.0	-	-	Crop group tolerance is being established
for Stover of Grain, Cereal, except Rice (Crop Group 16)

Corn, pop, stover	6.0	-	-

	Corn, sweet, stover	30.0	-	-

	Sorghum, grain, stover	5.0	-	-

	Wheat, hay	6.0	-	-	Crop group tolerance is being established for Hay of
Grain, Cereal, except Rice (Crop Group 16)

Wheat, straw	6.0	-	-	Crop group tolerance is being established for Straw
of Grain, Cereal, except Rice (Crop Group 16)



Cattle, fat	10	NA	2.0	Based on the recalculated MDBs for beef cattle
(20.9 ppm), dairy cattle (27.1 ppm) and swine (3.21 ppm) and the residue
data from the available cattle feeding study, tolerances for livestock
commodities can be substantially reduced.

Cattle, meat	0.4	NA	0.10

	Cattle, meat byproducts	0.4	NA	0.10

	Goat, fat	10	NA	2.0

	Goat, meat	0.4	NA	0.05

	Goat, meat byproducts	0.4	NA	0.05

	Hog, fat	10	NA	0.5

	Hog, meat	0.4	NA	0.01

	Hog, meat byproducts	0.4	NA	0.01

	Horse, fat	10	NA	2.0

	Horse, meat	0.4	NA	0.05

	Horse, meat byproducts	0.4	NA	0.05

	Milk	1.0	NA	0.2

	Milk, fat	30	NA	5.0

	Sheep, fat	10	NA	2.0

	Sheep, meat	0.4	NA	0.05

	Sheep, meat byproducts	0.4	NA	0.05

	

NA = not applicable

1 Regionally restricted tolerances for grass grown in CA, OR, ID and WA.

2 Forage tolerances are established for wheat (5.0 ppm), field corn (3.0
ppm), sweet corn (15 ppm), and sorghum (2.0 ppm)

3 Stover tolerances are established for field corn (6.0 ppm), popcorn
(6.0 ppm), sweet corn (30 ppm), and sorghum (5.0 ppm)

4 A straw tolerance is established for wheat (6.0 ppm)

5 A hay tolerance is established for wheat (6.0 ppm)

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Cyfluthrin and beta-Cyfluthrin		Barcode:  D349871

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Cyfluthrin and beta-Cyfluthrin		Barcode:  D349871

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