Document ID: EPA-HQ-OPP-2003-0348-0026
Agency: epa
Document Type: Supporting & Related Material
Title: 
Posted Date: 2006-07-26T04:00Z

Page
1
of
8
Revised
Appendix
B.
Data
Supporting
Guideline
Requirements
for
the
Reregistration
of
Propanil
GUIDE
TO
APPENDIX
B
Appendix
B
contains
a
listing
of
data
requirements
which
support
the
reregistration
for
active
ingredients
within
the
chemical
case
covered
by
this
RED
and
Amendment
to
the
RED.
It
contains
generic
data
requirements
that
apply
in
all
products,
including
data
requirements
for
which
a
"
typical
formulation"
is
the
test
substance.

The
data
table
is
organized
in
the
following
formats:
Page
2
of
8
1.
Data
Requirement
(
Columns
1,
2
&
3).
The
data
requirements
are
listed
in
the
order
of
New
Guideline
Number
and
appear
in
40
CFR
§
158.
The
reference
numbers
accompanying
each
test
refer
to
the
test
protocols
set
in
the
Pesticide
Assessment
Guidance,
which
are
available
from
the
National
Technical
Information
Service,
5285
Port
Royal
Road,
Springfield,
VA
22161­
0002,
(
703)
487­
4650.

2.
Use
Pattern
(
Column
4).
This
column
indicates
the
use
patterns
for
which
the
data
requirements
apply.
The
following
letter
designations
are
used
for
the
given
use
patterns.

A.
Terrestrial
food
B.
Terrestrial
feed
C.
Terrestrial
nonfood
D.
Aquatic
food
E.
Aquatic
nonfood
outdoor
F.
Aquatic
nonfood
industrial
G.
Aquatic
nonfood
residential
H.
Greenhouse
food
I.
Greenhouse
nonfood
J.
Forestry
K.
Residential
L.
Indoor
food
M.
Indoor
nonfood
N.
Indoor
medical
O.
Indoor
residential
3.
Bibliographical
Citation
(
Column
5).
If
the
Agency
has
acceptable
data
in
its
files,
this
column
lists
the
identification
number
of
each
study.
Normally,
this
is
the
Master
Record
Identification
(
MRID)
Number,
but
may
be
a
"
GS"
number
if
no
MRID
number
has
been
assigned.
Refer
to
the
Bibliography
(
Appendix
D)
for
a
complete
citation
of
the
study.
Page
3
of
8
Appendix
B.
Data
Supporting
Guideline
Requirements
for
the
Reregistration
of
Propanil
New
Guideline
Number
Old
Guideline
Number
Requirement
Use
Pattern
Bibliographical
Citation(
s)

PRODUCT
USE
CHEMISTRY
830.1550
61­
1
Product
Identity
and
Composition
All
830.1600
61­
2A
Starting
Materials
and
Manufacturing
Process
All
830.1620
Description
of
Production
Process
All
830.1670
61­
2B
Discussion
of
Formation
of
Impurities
All
40477301,
44681701
830.1700
62­
1
Preliminary
Analysis
All
830.1750
62­
2
Certification
of
Limits
All
40477301,
43969201,
44681702
830.1800
62­
3
Enforcement
Analytical
Method
All
40477301,
43969201,
44681703­
4
830.6302
63­
2
Color
All
830.6303
63­
3
Physical
State
All
830.6304
63­
4
Odor
All
830.7200
63­
5
Melting
Point/
Melting
Range
All
40477302,
44751501
830.7220
63­
6
Boiling
Point/
Boiling
Range
All
40900201
830.7300
63­
7
Density,
Relative
Density,
Bulk
Density
All
40477302,
44751501
830.7840
830.7860
63­
8
Solubility
All
40477302
830.7950
63­
9
Vapor
Pressure
All
40477302,
40900201,
40923201
830.7550
63­
11
Octanol/
Water
Partition
Coefficient
All
00150488
830.7000
63­
12
pH
of
Water
Solutions
or
Suspensions
All
44751501
830.6313
63­
13
Stability
All
40477302,
44751501
830.6314
63­
14
Oxidizing/
Reducing
Action
All
830.6316
63­
16
Explodability
All
830.6317
63­
17
Storage
Stability
All
830.6320
63­
20
Corrosion
Characteristics
All
44751501
ECOLOGICAL
EFFECTS
71­
1A
Avian
Acute
Oral
Toxicity,
Bobwhite
Quail
A,
B,
D
41361001
850.2100
71­
1B
Avian
Acute
Oral
Toxicity,
Mallard
Duck
A,
B,
D
41360701,
Acc.
No.
246087
Page
4
of
8
New
Guideline
Number
Old
Guideline
Number
Requirement
Use
Pattern
Bibliographical
Citation(
s)

Avian
Subacute
Dietary
Toxicity,
Bobwhite
Quail
A,
B,
D
41361101,
Acc.
No.
246413
71­
2A
Avian
Subacute
Dietary
Toxicity,
Bobwhite
Quail
on
3,4­
DCA
A,
B,
D
Data
Gap
850.2200
71­
2B
Avian
Subacute
Dietary
Toxicity,
Mallard
Duck
A,
B,
D
41360701,
Acc.
No.
246087
850.2300
71­
4A
Avian
Reproduction,
Bobwhite
Quail
on
Parent
Propanil
and
3,4­
DCA
A,
B,
D
Data
Gap
850.2300
71­
4B
Avian
Reproduction,
Mallard
Duck
on
Parent
Propanil
and
3,4­
DCA
A,
B,
D
Data
Gap
71­
5A
Simulated
Field
Study
A,
B,
D
Reserved
850.2500
71­
5B
Actual
Field
Study
A,
B,
D
Reserved
Fish
Toxicity,
Bluegill
Sunfish
A,
B,
D
40098001,
41359801,
41360201,
Acc.
No.
246087,
Acc.
No.
249347
72­
1A
Fish
Toxicity,
Bluegill
Sunfish
on
3,4­
DCA
A,
B,
D
Data
Gap
Fish
Toxicity,
Rainbow
Trout
A,
B,
D
40098001,
41359801,
41360201,
Acc.
No.
246087,
Acc.
No.
249347
850.1075
72­
1C
Fish
Toxicity,
Rainbow
Trout
on
3,4­
DCA
A,
B,
D
Data
Gap
Invertebrate
Toxicity
A,
B,
D
41776801,
Acc.
No.
249347
850.1010
72­
2A
Invertebrate
Toxicity
on
3,4­
DCA
A,
B,
D
Data
Gap
None
72­
3A
Estuarine/
Marine
Fish
Acute
Toxicity
A,
B,
D
41776001
850.1025
72­
3B
Estuarine/
Marine
Mollusk
Acute
Toxicity
A,
B,
D
41777101,
42253100
850.1035
72­
3C
Estuarine/
Marine
Invertebrate
Acute
Toxicity
A,
B,
D
41776901,
42253101,
Data
Gap
Fish
­
Early
Life
Stage
A,
B,
D
41776501,
42259601,
42479601,
Acc.
No.
095187
850.1300
72­
4A
Fish
­
Early
Life
Stage
on
3,4­
DCA
A,
B,
D
Data
Gap
Estuarine/
Marine
Invertebrate
Life
Cycle
A,
B,
D
41776001,
42145601
850.1350
72­
4B
Estuarine/
Marine
Invertebrate
Life
Cycle
on
3,4­
DCA
A,
B,
D
Data
Gap
850.1400
72­
4C
Early
Life
Stage,
Freshwater
Fish
(
Daphnia)
A,
B,
D
42145601,
41776601
Page
5
of
8
New
Guideline
Number
Old
Guideline
Number
Requirement
Use
Pattern
Bibliographical
Citation(
s)

850.1500
72­
5
Life
Cycle
Fish
A,
B,
D
41776001,
42145601,
42475301
850.1710
72­
6
Aquatic
Organism
Accumulation
Study
A,
B,
D
Reserved
72­
7A
Simulated
Field
Testing
for
Aquatic
Organisms
A,
B,
D
Reserved
850.1950
72­
7B
Actual
Field
Testing
for
Aquatic
Organisms
A,
B,
D
Reserved
850.4100
122­
1A
Seedling
Emergence,
Tier
1
on
3,4­
DCA
A,
B,
D
Data
Gap
850.4150
122­
1B
Vegetative
Vigor,
Tier
1
on
3,4­
DCA
A,
B,
D
Data
Gap
850.4225
123­
1A
Seedling
Germination
and
Seedling
Emergence,
Tier
2
on
TEP
A,
B,
D
43069901
850.4250
123­
1B
Vegetative
Vigor,
Tier
2
on
TEP
A,
B,
D
Data
Gap
850.4400
123­
2B
Aquatic
Plant
Toxicity
Test
Using
Lemma
spp.,
Tier
2
A,
B,
D
41777201,
41777301,
41777401,
41777501,
41776701
850.3020
141­
1
Honey
Bee
Acute
Contact
Toxicity
A,
B,
D
00018842
TOXICOLOGY
870.1100
81­
1
Acute
Oral
Toxicity,
Rat
All
00008722,
40070201,
41360801
870.1200
81­
2
Acute
Dermal
Toxicity,
Rabbit/
Rat
All
00008722,
40070202,
41360901
870.1300
81­
3
Acute
Inhalation
Toxicity,
Rat
All
00008423,
40070203,
41265901,
41415501
870.2400
81­
4
Primary
Eye
Irritation,
Rabbit
All
00008430,
41360501
870.2500
81­
5
Primary
Skin
Irritation
All
00008430,
40070202,
41360601
870.2600
81­
6
Dermal
Sensitization
All
00008430,
40070204,
40871906,
40914506,
41319701,
41319801,
41360401
870.3100
82­
1A
90­
Day
Subchronic
Feeding,
Rodent
A,
B,
D
00015459,
00046259,
40402901
870.3150
82­
1B
90­
Day
Subchronic
Feeding,
Nonrodent
(
Dog)
A,
B,
D
42962901,
43303201
870.3200
82­
2
21­
Day
Dermal,
Rabbit/
Rat
A,
B,
D
41777001,
41961800­
01
870.3465
82­
4
90­
Day
Inhalation,
Rat
A,
B,
D
Data
Gap
83­
1A
Chronic
Feeding
Toxicity,
Rodent
A,
B,
D
43303201,
43677801
870.4100
83­
1B
Chronic
Feeding
Toxicity,
Nonrodent
(
Dog)
A,
B,
D
42962901
870.4200
83­
2A
Chronic
Carcinogenicity
(
Feeding),
Rat
A,
B,
D
00015419,
00155215,
43303201,
43391701,
43677801
Page
6
of
8
New
Guideline
Number
Old
Guideline
Number
Requirement
Use
Pattern
Bibliographical
Citation(
s)

83­
2B
Chronic
Carcinogenicity
(
Feeding),
Mouse
A,
B,
D
00155215,
43391701
83­
3A
Prenatal
Developmental
Toxicity,
Rat
A,
B,
D
00058588
870.3700
83­
3B
Prenatal
Developmental
Toxicity,
Rabbit
A,
B,
D
00058589,
45518801
870.3800
83­
4
2­
Generation
Reproduction,
Rat
A,
B,
D
00036091,
44604301
870.4300
83­
5
Combined
Chronic
Toxicity/
Carcinogenicity
Study,
Rat
A,
B,
D
43303201
870.5140
84­
2A
Gene
Mutation
(
Ames
Test)
A,
B,
D
00028625,
00155084­
5
870.5375
84­
2B
Structural
Chromosomal
Aberration
A,
B,
D
00155083
870.5100
Bacterial
Reverse
Gene
Mutation
Assay
Test
A,
B,
D
00155085
870.5300
84­
2
Detection
of
Gene
Mutations
in
Somatic
Cells
in
Culture,
Mammalian
A,
B,
D
00155084
870.5500
84­
4
Other
Genotoxic
Effects
A,
B,
D
00028625
870.7485
85­
1
General
Metabolism,
Rat
A,
B,
D
41796400­
2
870.7800
85­
7
Immunotoxicity
Study,
Rat
A,
B,
D
Data
Gap
OCCUPATIONAL/
RESIDENTIAL
EXPOSURE
875.2100
132­
1A
Foliar
Residue
Dissipation
A,
B,
D
Reserved
875.2400
133­
3
Dermal
Passive
Dosimetry
Exposure
A,
B,
D
Reserved
875.2500
133­
4
Inhalation
Passive
Dosimetry
Exposure
A,
B,
D
00143618,
Reserved
875.1100
231
Estimation
of
Dermal
Exposure
at
Outdoor
Sites
A,
B,
D
46075501,
46147801,
Data
Gap
ENVIRONMENTAL
FATE
None
160­
5
Chemical
Identity
A,
B,
D
41066601
Hydrolysis
A,
B,
D
41066601
835.2120
161­
1
Hydrolysis
on
3,4­
DCA
A,
B,
D
Data
Gap
Photodegradation,
Water
A,
B,
D
41074701
835.2240
161­
2
Photodegradation,
Water
on
3,4­
DCA
A,
B,
D
Data
Gap
835.2410
161­
3
Photodegradation,
Soil
A,
B,
D
42820401
835.2370
161­
4
Photodegradation,
Air
A,
B,
D
41537801
835.4100
162­
1
Aerobic
Soil
Metabolism
Study
A,
B,
D
41537801,
42057801
835.4200
162­
2
Anaerobic
Soil
Metabolism
Study
A,
B,
D
835.4400
162­
3
Anaerobic
Aquatic
Metabolism
Study
A,
B,
D
41848701,
41872601
Page
7
of
8
New
Guideline
Number
Old
Guideline
Number
Requirement
Use
Pattern
Bibliographical
Citation(
s)

835.4300
162­
4
Aerobic
Aquatic
Metabolism
Study
A,
B,
D
41848701,
41872601
835.1230
163­
1
Leaching
and
Adsorption/
Desorption
on
3,4­
DCA
A,
B,
D
42780401,
43217201,
Data
Gap
835.1410
163­
2
Laboratory
Volatilization
from
Soil
A,
B,
D
Waived
835.6200
164­
2
Aquatic
Field
Dissipation
A,
B,
D
42200401,
42200501
835.6500
164­
5
Long­
Term
Terrestrial
Field
Dissipation
A,
B,
D
Reserved
835.7100
166­
1
Small
Scale
Prospective
Ground
Water
A,
B,
D
Reserved
RESIDUE
CHEMISTRY
860.1850
165­
1
Confined
Accumulation
in
Rotational
Crops
A,
B,
D
42963001
860.1900
165­
2
Field
Accumulation
in
Rotational
Crops
A,
B,
D
Reserved
None
165­
5
Bioaccumulation
in
Aquatic
Nontarget
Organisms
A,
B,
D
Reserved
171­
4A
Nature
of
the
Residue,
Plants
A,
B,
D
00035588­
9,
00035684,
00036100,
00052347­
50,
42209201,
42382901­
2,
43285401,
43372201
171­
4B
Nature
of
the
Residue,
Livestock
A,
B,
D
00035697­
9,
00035905,
00067394,
41754401,
41755301,
41848801,
41983901
860.1300
None
Nature
of
the
Residue,
Crayfish
A,
B,
D
41848901,
41849101,
42301001
171­
4C
Residue
Analytical
Method,
Plants
A,
B,
D
00035587,
00055547,
00067394,
00076113,
00111367,
00111388,
43196001,
44748202,
43355201
860.1340
171­
4D
Residue
Analytical
Method,
Animals
A,
B,
D
00055547,
00111367,
Reserved
860.1380
171­
4E
Storage
Stability
A,
B,
D
00035683,
42200401,
42200501,
44748201,
43157001­
2
171­
4F
Magnitude
of
Residues
in
Potable
Water
A,
B,
D
00035688,
42200401,
42200501,
43406501,

171­
4G
Magnitude
of
Residues
in
Fish
(
Crayfish)
A,
B,
D
00035692,
00111394,
43748101
860.1400
171­
4H
Magnitude
of
Residues
in
Irrigated
Crops
A,
B,
D
00035688
860.1480
171­
4J
Magnitude
of
Residues
in
Meat,
Milk,
Poultry
and
Eggs
A,
B,
D
00035694­
5,
44748201,
44550101
860.1500
171­
4K
Crop
Field
Trials
(
Cereal
Grains
Group)
A,
B,
D
00035687­
8,
00055546,
00078930,
00111370,
00111373,
Page
8
of
8
New
Guideline
Number
Old
Guideline
Number
Requirement
Use
Pattern
Bibliographical
Citation(
s)

Crop
Field
Trials
(
Grass
Forage,
Fodder
and
Straw
Group)
A,
B,
D
43282801,
42237301
Crop
Field
Trials
(
Rice)
A,
B,
D
43157001,
43282801,
42237101,

42237201
Processed
Food
(
Barley,
Oats
and
Wheat)
A,
B,
D
860.1520
171­
4L
Processed
Food
(
Rice)
A,
B,
D
00035576,
00035687­
8,
00052347,
42417401,
Waived
860.1360
171­
4M
Multiresidue
Methods
A,
B,
D
41755001
OTHER
None
None
3
0­
Day
Repeated
Dose
Oral
(
Dietary)
Toxicity,
Rat
A,
B,
D
45829301
None
None
Aquatic
Non­
target
Organism
Exposure
in
Rice
Paddies
(
RICEWQ
model)
A,
B,
D
45940801
(
D290202)