Document ID: EPA-HQ-OPPT-2011-0941-0001
Agency: epa
Document Type: Rule
Title: Significant New Use Rules on Certain Chemical Substances
Posted Date: 2012-09-21T04:00Z

[Federal Register Volume 77, Number 184 (Friday, September 21, 2012)]
[Rules and Regulations]
[Pages 58665-58706]
From the Federal Register Online via the Government Printing Office [www.gpo.gov]
[FR Doc No: 2012-23235]

[[Page 58665]]

Vol. 77

Friday,

No. 184

September 21, 2012

Part IV

Environmental Protection Agency

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40 CFR Parts 9 and 721

Significant New Use Rules on Certain Chemical Substances; Final Rule

  Federal Register / Vol. 77 , No. 184 / Friday, September 21, 2012 / 
Rules and Regulations  

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ENVIRONMENTAL PROTECTION AGENCY

40 CFR Parts 9 and 721

[EPA-HQ-OPPT-2011-0941; FRL-9357-2]
RIN 2070-AB27

Significant New Use Rules on Certain Chemical Substances

AGENCY: Environmental Protection Agency (EPA).

ACTION: Direct final rule.

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SUMMARY: EPA is promulgating significant new use rules (SNURs) under 
the Toxic Substances Control Act (TSCA) for 107 chemical substances 
which were the subject of premanufacture notices (PMNs). Eight of these 
chemical substances are subject to TSCA consent orders issued by EPA. 
This action requires persons who intend to manufacture, import, or 
process any of these 107 chemical substances for an activity that is 
designated as a significant new use by this rule to notify EPA at least 
90 days before commencing that activity. The required notification will 
provide EPA with the opportunity to evaluate the intended use and, if 
necessary, to prohibit or limit that activity before it occurs.

DATES: This rule is effective on November 20, 2012. For purposes of 
judicial review, this rule shall be promulgated at 1 p.m. (e.s.t.) on 
October 5, 2012.
    Written adverse or critical comments, or notice of intent to submit 
adverse or critical comments, on one or more of these SNURs must be 
received on or before October 22, 2012 (see Unit VI. of the 
SUPPLEMENTARY INFORMATION).
    For additional information on related reporting requirement dates, 
see Units I.A., VI., and VII. of the SUPPLEMENTARY INFORMATION.

ADDRESSES: Submit your comments, identified by docket identification 
(ID) number EPA-HQ-OPPT-2011-0941, by one of the following methods:
     Federal eRulemaking Portal: http://www.regulations.gov. 
Follow the online instructions for submitting comments.
     Mail: Document Control Office (7407M), Office of Pollution 
Prevention and Toxics (OPPT), Environmental Protection Agency, 1200 
Pennsylvania Ave. NW., Washington, DC 20460-0001.
     Hand Delivery: OPPT Document Control Office (DCO), EPA 
East, Rm. 6428, 1201 Constitution Ave. NW., Washington, DC. Attention: 
Docket ID Number EPA-HQ-OPPT-2011-0941. The DCO is open from 8 a.m. to 
4 p.m., Monday through Friday, excluding legal holidays. The telephone 
number for the DCO is (202) 564-8930. Such deliveries are only accepted 
during the DCO's normal hours of operation, and special arrangements 
should be made for deliveries of boxed information.
    Instructions: Direct your comments to docket ID number EPA-HQ-OPPT-
2011-0941. EPA's policy is that all comments received will be included 
in the docket without change and may be made available online at http://www.regulations.gov, including any personal information provided, 
unless the comment includes information claimed to be Confidential 
Business Information (CBI) or other information whose disclosure is 
restricted by statute. Do not submit information that you consider to 
be CBI or otherwise protected through regulations.gov or email. The 
regulations.gov Web site is an ``anonymous access'' system, which means 
EPA will not know your identity or contact information unless you 
provide it in the body of your comment. If you send an email comment 
directly to EPA without going through regulations.gov, your email 
address will be automatically captured and included as part of the 
comment that is placed in the docket and made available on the 
Internet. If you submit an electronic comment, EPA recommends that you 
include your name and other contact information in the body of your 
comment and with any disk or CD-ROM you submit. If EPA cannot read your 
comment due to technical difficulties and cannot contact you for 
clarification, EPA may not be able to consider your comment. Electronic 
files should avoid the use of special characters, any form of 
encryption, and be free of any defects or viruses.
    Docket: All documents in the docket are listed in the docket index 
available at http://www.regulations.gov. Although listed in the index, 
some information is not publicly available, e.g., CBI or other 
information whose disclosure is restricted by statute. Certain other 
material, such as copyrighted material, will be publicly available only 
in hard copy. Publicly available docket materials are available 
electronically at http://www.regulations.gov, or, if only available in 
hard copy, at the OPPT Docket. The OPPT Docket is located in the EPA 
Docket Center (EPA/DC) at Rm. 3334, EPA West Bldg., 1301 Constitution 
Ave. NW., Washington, DC. The EPA/DC Public Reading Room hours of 
operation are 8:30 a.m. to 4:30 p.m., Monday through Friday, excluding 
legal holidays. The telephone number of the EPA/DC Public Reading Room 
is (202) 566-1744, and the telephone number for the OPPT Docket is 
(202) 566-0280. Docket visitors are required to show photographic 
identification, pass through a metal detector, and sign the EPA visitor 
log. All visitor bags are processed through an X-ray machine and 
subject to search. Visitors will be provided an EPA/DC badge that must 
be visible at all times in the building and returned upon departure.

FOR FURTHER INFORMATION CONTACT: For technical information contact: 
Kenneth Moss, Chemical Control Division (7405M), Office of Pollution 
Prevention and Toxics, Environmental Protection Agency, 1200 
Pennsylvania Ave. NW., Washington, DC 20460-0001; telephone number: 
(202) 564-9232; email address: moss.kenneth@epa.gov.
    For general information contact: The TSCA-Hotline, ABVI-Goodwill, 
422 South Clinton Ave. Rochester, NY 14620; telephone number: (202) 
554-1404; email address: TSCA-Hotline@epa.gov.

SUPPLEMENTARY INFORMATION:

I. General Information

A. Does this action apply to me?

    You may be potentially affected by this action if you manufacture, 
import, process, or use the chemical substances contained in this rule. 
Potentially affected entities may include, but are not limited to:
     Manufacturers, importers, or processors of one or more 
subject chemical substances (NAICS codes 325 and 324110), e.g., 
chemical manufacturing and petroleum refineries.
    This listing is not intended to be exhaustive, but rather provides 
a guide for readers regarding entities likely to be affected by this 
action. Other types of entities not listed in this unit could also be 
affected. The North American Industrial Classification System (NAICS) 
codes have been provided to assist you and others in determining 
whether this action might apply to certain entities. To determine 
whether you or your business may be affected by this action, you should 
carefully examine the applicability provisions in Sec.  721.5. If you 
have any questions regarding the applicability of this action to a 
particular entity, consult the technical person listed under FOR 
FURTHER INFORMATION CONTACT.
    This action may also affect certain entities through pre-existing 
import certification and export notification rules under TSCA. Chemical 
importers are subject to the TSCA section 13 (15 U.S.C. 2612) import 
certification requirements promulgated at 19 CFR 12.118 through 12.127; 
see also 19 CFR 127.28. Chemical importers must certify that the 
shipment of the chemical substance complies with all applicable

[[Page 58667]]

rules and orders under TSCA. Importers of chemicals subject to these 
SNURs must certify their compliance with the SNUR requirements. The EPA 
policy in support of import certification appears at 40 CFR part 707, 
subpart B. In addition, any persons who export or intend to export a 
chemical substance that is the subject of this rule are subject to the 
export notification provisions of TSCA section 12(b) (15 U.S.C. 
2611(b)) (see Sec.  [emsp14]721.20), and must comply with the export 
notification requirements in 40 CFR part 707, subpart D.

B. What should I consider as I prepare my comments for EPA?

    1. Submitting CBI. Do not submit this information to EPA through 
regulations.gov or email. Clearly mark the part or all of the 
information that you claim to be CBI. For CBI information in a disk or 
CD-ROM that you mail to EPA, mark the outside of the disk or CD-ROM as 
CBI and then identify electronically within the disk or CD-ROM the 
specific information that is claimed as CBI. In addition to one 
complete version of the comment that includes information claimed as 
CBI, a copy of the comment that does not contain the information 
claimed as CBI must be submitted for inclusion in the public docket. 
Information so marked will not be disclosed except in accordance with 
procedures set forth in 40 CFR part 2.
    2. Tips for preparing your comments. When submitting comments, 
remember to:
    i. Identify the document by docket ID number and other identifying 
information (subject heading, Federal Register date and page number).
    ii. Follow directions. The Agency may ask you to respond to 
specific questions or organize comments by referencing a Code of 
Federal Regulations (CFR) part or section number.
    iii. Explain why you agree or disagree; suggest alternatives and 
substitute language for your requested changes.
    iv. Describe any assumptions and provide any technical information 
and/or data that you used.
    v. If you estimate potential costs or burdens, explain how you 
arrived at your estimate in sufficient detail to allow for it to be 
reproduced.
    vi. Provide specific examples to illustrate your concerns and 
suggest alternatives.
    vii. Explain your views as clearly as possible, avoiding the use of 
profanity or personal threats.
    viii. Make sure to submit your comments by the comment period 
deadline identified.

II. Background

A. What action is the agency taking?

    EPA is promulgating these SNURs using direct final procedures. 
These SNURs will require persons to notify EPA at least 90 days before 
commencing the manufacture, import, or processing of a chemical 
substance for any activity designated by these SNURs as a significant 
new use. Receipt of such notices allows EPA to assess risks that may be 
presented by the intended uses and, if appropriate, to regulate the 
proposed use before it occurs. Additional rationale and background to 
these rules are more fully set out in the preamble to EPA's first 
direct final SNUR published in the Federal Register issue of April 24, 
1990 (55 FR 17376) (April 24, 1990 SNUR). Consult that preamble for 
further information on the objectives, rationale, and procedures for 
SNURs and on the basis for significant new use designations, including 
provisions for developing test data.

B. What is the agency's authority for taking this action?

    Section 5(a)(2) of TSCA (15 U.S.C. 2604(a)(2)) authorizes EPA to 
determine that a use of a chemical substance is a ``significant new 
use.'' EPA must make this determination by rule after considering all 
relevant factors, including the four bulleted TSCA section 5(a)(2) 
factors listed in Unit III. Once EPA determines that a use of a 
chemical substance is a significant new use, TSCA section 5(a)(1)(B) 
requires persons to submit a significant new use notice (SNUN) to EPA 
at least 90 days before they manufacture, import, or process the 
chemical substance for that use. Persons who must report are described 
in Sec.  721.5.

C. Applicability of General Provisions

    General provisions for SNURs appear in 40 CFR part 721, subpart A. 
These provisions describe persons subject to the rule, recordkeeping 
requirements, exemptions to reporting requirements, and applicability 
of the rule to uses occurring before the effective date of the rule. 
Provisions relating to user fees appear at 40 CFR part 700. According 
to Sec.  [emsp14]721.1(c), persons subject to these SNURs must comply 
with the same notice requirements and EPA regulatory procedures as 
submitters of PMNs under TSCA section 5(a)(1)(A). In particular, these 
requirements include the information submission requirements of TSCA 
section 5(b) and 5(d)(1), the exemptions authorized by TSCA sections 
5(h)(1), 5(h)(2), 5(h)(3), and 5(h)(5), and the regulations at 40 CFR 
part 720. Once EPA receives a SNUN, EPA may take regulatory action 
under TSCA section 5(e), 5(f), 6, or 7 to control the activities for 
which it has received the SNUN. If EPA does not take action, EPA is 
required under TSCA section 5(g) to explain in the Federal Register its 
reasons for not taking action.

III. Significant New Use Determination

    Section 5(a)(2) of TSCA states that EPA's determination that a use 
of a chemical substance is a significant new use must be made after 
consideration of all relevant factors, including:
     The projected volume of manufacturing and processing of a 
chemical substance.
     The extent to which a use changes the type or form of 
exposure of human beings or the environment to a chemical substance.
     The extent to which a use increases the magnitude and 
duration of exposure of human beings or the environment to a chemical 
substance.
     The reasonably anticipated manner and methods of 
manufacturing, processing, distribution in commerce, and disposal of a 
chemical substance.
    In addition to these factors enumerated in TSCA section 5(a)(2), 
the statute authorized EPA to consider any other relevant factors.
    To determine what would constitute a significant new use for the 
107 chemical substances that are the subject of these SNURs, EPA 
considered relevant information about the toxicity of the chemical 
substances, likely human exposures and environmental releases 
associated with possible uses, taking into consideration the four 
bulleted TSCA section 5(a)(2) factors listed in this unit.

IV. Substances Subject to This Rule

    EPA is establishing significant new use and recordkeeping 
requirements for 107 chemical substances in 40 CFR part 721, subpart E. 
In this unit, EPA provides the following information for each chemical 
substance:
     PMN number.
     Chemical name (generic name, if the specific name is 
claimed as CBI).
     Chemical Abstracts Service (CAS) number (if assigned for 
non-confidential chemical identities).
     Basis for the TSCA section 5(e) consent order or, for non-
section 5(e) SNURs, the basis for the SNUR (i.e., SNURs without TSCA 
section 5(e) consent orders).
     Tests recommended by EPA to provide sufficient information 
to evaluate the chemical substance (see Unit VIII. for more 
information).
     CFR citation assigned in the regulatory text section of 
this rule.

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    The regulatory text section of this rule specifies the activities 
designated as significant new uses. Certain new uses, including 
production volume limits (i.e., limits on manufacture and importation 
volume) and other uses designated in this rule may be claimed as CBI. 
Unit IX. discusses a procedure companies may use to ascertain whether a 
proposed use constitutes a significant new use.
    This rule includes 8 PMN substances (P-00-346, P-01-470, P-02-120, 
P-02-285, P-04-834, P-10-58, P-10-59, and P-10-60) for which EPA 
determined, pursuant to TSCA section 5(e), that uncontrolled 
manufacture, import, processing, distribution in commerce, use, and 
disposal may present an unreasonable risk of injury to human health and 
the environment. Accordingly, these substances are subject to ``risk-
based'' consent orders under TSCA section 5(e)(1)(A)(ii)(I). Those 
consent orders require protective measures to limit exposures or 
otherwise mitigate the potential unreasonable risk. The so-called 
``5(e) SNURs'' on these PMN substances are promulgated pursuant to 
Sec.  721.160, and are based on and consistent with the provisions in 
the underlying consent orders. The section 5(e) SNURs designate as a 
``significant new use'' the absence of the protective measures required 
in the corresponding consent orders.
    Where EPA determined that the PMN substance may present an 
unreasonable risk of injury to human health via inhalation exposure, 
the SNUR usually requires, among other things, that potentially exposed 
employees wear specified respirators unless actual measurements of the 
workplace air show that air-borne concentrations of the PMN substance 
are below a New Chemical Exposure Limit (NCEL) that is established by 
EPA to provide adequate protection to human health. In addition to the 
actual NCEL concentration, the comprehensive NCELs provisions, which 
are modeled after Occupational Safety and Health Administration (OSHA) 
Permissible Exposure Limits (PELs) provisions, include requirements 
addressing performance criteria for sampling and analytical methods, 
periodic monitoring, respiratory protection, and recordkeeping. 
However, no comparable NCEL provisions currently exist in 40 CFR part 
721, subpart B, for SNURs. Therefore, for these cases, the individual 
SNURs in 40 CFR part 721, subpart E, will state that persons subject to 
the SNUR who wish to pursue NCELs as an alternative to the Sec.  721.63 
respirator requirements may request to do so under Sec.  721.30.
    This rule also includes SNURs on 99 PMN substances that are not 
subject to consent orders under TSCA section 5(e). In these cases, for 
a variety of reasons, EPA did not find that the use scenario described 
in the PMN triggered the determinations set forth under TSCA section 
5(e). However, EPA does believe that certain changes from the use 
scenario described in the PMN could result in increased exposures, 
thereby constituting a ``significant new use.'' These so-called ``non-
5(e) SNURs'' are promulgated pursuant to Sec.  721.170. EPA has 
determined that every activity designated as a ``significant new use'' 
in all non-5(e) SNURs issued under Sec.  721.170 satisfies the two 
requirements stipulated in Sec.  721.170(c)(2), i.e., these significant 
new use activities, ``(i) are different from those described in the 
premanufacture notice for the substance, including any amendments, 
deletions, and additions of activities to the premanufacture notice, 
and (ii) may be accompanied by changes in exposure or release levels 
that are significant in relation to the health or environmental 
concerns identified'' for the PMN substance.

PMN Number P-96-308

    Chemical name: Aminoalkanol (generic).
    CAS number: Not available.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as a chemical intermediate. 
Based on structure-activity relationship (SAR) analysis of the 
potential reaction of the PMN substance with nitrosating agents, and by 
analogy to monoethanolamine, diethanolamine and dimethylisopropylamine, 
EPA identified concerns for skin, eye, liver, kidney, lung, bone 
marrow, brain, testes, heart, and blood toxicity from exposure to the 
PMN substance via inhalation and dermal exposures, and the 
gastrointestinal (GI) tract. In addition, based on ecological 
structure-activity relationship (EcoSAR) analysis of test data on 
analogous aliphatic amines, EPA predicts toxicity to aquatic organisms 
may occur at concentrations that exceed 600 ppb of the PMN substance in 
surface waters. For the use described in the PMN, EPA does not expect 
dermal or inhalation exposures to manufacturing or processing workers 
or other targeted populations, nor does it expect releases to surface 
waters. Therefore, EPA has not determined that the proposed 
manufacturing, processing, or use of the substance may present an 
unreasonable risk. EPA has determined, however, that any use of the 
substance other than as described in the PMN, or any use of the 
substance resulting in surface water concentrations exceeding 600 ppb 
may cause serious health effects and significant adverse environmental 
effects. Based on this information, the PMN substance meets the concern 
criteria at Sec.  721.170(b)(3)(i), (b)(3)(ii), and (b)(4)(ii).
    Recommended testing: EPA has determined that the results of a 90-
day inhalation toxicity test (OPPTS Test Guideline 870.3465) with a 
functional observational battery and histopathology; a prenatal 
developmental toxicity test (OPPTS Test Guideline 870.3700); a fish 
acute toxicity test, freshwater and marine (OPPTS Test Guideline 
850.1075); a fish acute toxicity test mitigated by humic acid (OPPTS 
Test Guideline 850.1085); an aquatic invertebrate acute toxicity test, 
freshwater daphnids (OPPTS Test Guideline 850.1010); and an algal 
toxicity test (OCSPP Test Guideline 850.4500) would help to 
characterize the human health and environmental effect of the PMN 
substance.
    CFR citation: 40 CFR 721.10427.

PMN Numbers P-96-1021 and P-96-1022

    Chemical names: (P-96-1021) Fatty acids, C18-unsatd., 
dimers, reaction products with 1-piperazineethanamine and (P-96-1022) 
Fatty acids, C18-unsatd., dimers, reaction products with 1-
piperazineethanamine and tall-oil fatty acids.
    CAS numbers: (P-96-1021) 206565-90-4 and (P-96-1022) 206565-89-1.
    Basis for action: The consolidated PMN states that the substances 
will be used as water based epoxy curing agents. Based on EcoSAR 
analysis of test data on analogous aliphatic amines, EPA predicts 
toxicity to aquatic organisms may occur at concentrations that exceed 1 
ppb of the PMN substances in surface waters. As described in the PMN, 
the substances are not released to surface waters. Therefore, EPA has 
not determined that the proposed manufacturing, processing, or use of 
the PMN substances may present an unreasonable risk. EPA has 
determined, however, that any use of the substances resulting in 
surface water concentrations exceeding 1 ppb may cause significant 
adverse environmental effects. Based on this information, the PMN 
substances meet the concern criteria at Sec.  721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a 
modified semi-continuous activated

[[Page 58669]]

sludge (SCAS) test (OPPTS Test Guideline 835.3210); a fish acute 
toxicity test, freshwater and marine (OPPTS Test Guideline 850.1075); 
an aquatic invertebrate acute toxicity test, freshwater daphnids (OPPTS 
Test Guideline 850.1010); and an algal toxicity test (OCSPP Test 
Guideline 850.4500) on PMN P-96-1022 would help characterize the 
environmental effects of the PMN substances.
    CFR citations: 40 CFR 721.10428 (P-96-1021) and 40 CFR 721.10429 
(P-96-1022).

PMN Number P-97-823

    Chemical name: Tetra alkyl ammonium salt (generic).
    CAS number: Not available.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as a curing agent for 
coatings. Based on test data submitted on the PMN substance at varying 
concentrations, EPA identified concerns for ocular lethality for 
occupational exposures to the PMN substance at concentrations greater 
than 25 percent. For the use described in the PMN, significant worker 
exposures are not expected as the PMN substance is used at 
concentrations no greater than 25 percent, and the material safety data 
sheet (MSDS) provides the ocular lethality results from the submitted 
eye irritation studies. Therefore, EPA has not determined that the 
proposed manufacturing, processing, or use of the substance may present 
an unreasonable risk. EPA has determined, however, that any use of the 
substance without including the hazard communication warnings 
concerning the eye irritation test results in the MSDS, or any use of 
the substance in concentrations greater than 25 percent may cause 
serious health effects. Based on this information, the PMN substance 
meets the concern criteria at Sec.  721.170(b)(3)(i).
    Recommended testing: EPA has determined that the results of an 
acute eye irritation test (OPPTS Test Guideline 870.2400) on the PMN 
substance at concentrations greater than 25 percent would help 
characterize human health effects of the PMN substance.
    CFR citation: 40 CFR 721.10430.

PMN Numbers P-98-141 and P-98-142

    Chemical name: Phosphoric acid esters (generic).
    CAS number: Not available.
    Basis for action: The consolidated PMN states that the generic 
(non-confidential) use of the substances will be as metal extractants. 
Based on EcoSAR analysis of test data on analogous anionic surfactants, 
EPA predicts toxicity to aquatic organisms may occur at concentrations 
that exceed 100 ppb of the PMN substance in surface waters. As 
described in the PMN, the substance is not released to surface waters. 
Therefore, EPA has not determined that the proposed manufacturing, 
processing, or use of the PMN substance may present an unreasonable 
risk. EPA has determined, however, that any use of the substance 
resulting in surface water concentrations exceeding 100 ppb may cause 
significant adverse environmental effects. Based on this information, 
the PMN substance meets the concern criteria at Sec.  
721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a fish 
acute toxicity test, freshwater and marine (OPPTS Test Guideline 
850.1075); an aquatic invertebrate acute toxicity test, freshwater 
daphnids (OPPTS Test Guideline 850.1010); and an algal toxicity test 
(OCSPP Test Guideline 850.4500) on the PMN substances would help 
characterize the environmental effects of the PMN substances.
    CFR citation: 40 CFR 721.10431.

PMN Number P-98-1028

    Chemical name: 1,2,4,5,7,8-Hexoxonane, 3,6,9-triethyl-3,6,9-
trimethyl-.
    CAS number: 24748-23-0.
    Basis for action: The PMN states that the substance will be used as 
a viscosity modifier in the manufacture of polypropylene, manufactured 
and supplied as a solution in at least 40 percent mineral spirits. 
Based on EcoSAR analysis of test data on analogous peroxides, EPA 
predicts toxicity to aquatic organisms may occur if releases of the PMN 
substance to surface water, from uses other than as described in the 
PMN, exceed releases from the use described in the PMN. For the use 
described in the PMN, where the PMN substance is supplied as a solution 
of at least 40 percent mineral spirits, significant environmental 
releases are not expected. Therefore, EPA has not determined that the 
proposed manufacturing, processing, or use of the PMN substance may 
present an unreasonable risk. EPA has determined, however, that any use 
of the substance other than as a viscosity modifier, manufactured and 
supplied as a solution in at least 40 percent mineral spirits, in the 
manufacture of polypropylene may cause significant adverse 
environmental effects. Based on this information, the PMN substances 
meet the concern criteria at Sec.  721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a 
porous pot test (OPPTS Test Guideline 835.3220); a fish acute toxicity 
test, freshwater and marine (OPPTS Test Guideline 850.1075); an aquatic 
invertebrate acute toxicity test, freshwater daphnids (OPPTS Test 
Guideline 850.1010); and an algal toxicity test (OCSPP Test Guideline 
850.4500) would help characterize the environmental effects of the PMN 
substance.
    CFR citation: 40 CFR 721.10432.

PMN Number P-99-184

    Chemical name: Cyclopentene, 1,2,3,3,4,4,5,5-octafluoro-.
    CAS number: 559-40-0.
    Basis for action: The PMN states that the substance will be used as 
a dry etching agent and a chemical vapor deposition (CVD) agent for the 
production of semiconductors. Based on test data on the PMN substance, 
EPA identified concerns for acute toxicity, systemic toxicity, 
developmental toxicity, cardiac sensitization, and mutagenicity from 
inhalation exposures. As described in the PMN, the substance will be 
imported and not manufactured in the United States. As described in the 
PMN, EPA does not expect significant worker exposures during processing 
and use activities for the uses described in the PMN nor does it expect 
general population exposures for the uses described in the PMN. 
Therefore, EPA has not determined that the proposed processing or use 
may present an unreasonable risk. EPA has determined, however, that 
domestic manufacture, or any use of the substance other than as a dry 
etching agent and a CVD agent for the production of semiconductors may 
cause serious health effects. Based on this information, the PMN 
substance meets the concern criteria at Sec.  721.170(b)(3)(i).
    Recommended testing: EPA has determined that inhalation monitoring 
data, collected according to the EPA draft Inhalation Monitoring Data 
Collection Guidelines (located in the docket under docket ID number 
EPA-HQ-OPPT-2011-0941), would help characterize the human health 
effects of the PMN substance.
    CFR citations: 40 CFR 721.10433.

PMN Number P-99-214

    Chemical name: Cyclopentane, 1,1,2,2,3,3,4-heptafluoro-.
    CAS number: 15290-77-4.
    Basis for action: The PMN states that the substance will be used as 
a solvent and a cleaning and drying agent. Based on test data on the 
PMN substance, EPA identified concerns for acute, systemic,

[[Page 58670]]

and developmental toxicity, cardiac sensitization, and mutagenicity 
from inhalation exposures. As described in the PMN, the substance will 
be imported and not manufactured in the United States. As described in 
the PMN, EPA does not expect significant worker exposures during 
processing and use activities for the uses described in the PMN nor 
does it expect general population or consumer exposures for the uses 
described in the PMN. Therefore, EPA has not determined that the 
proposed processing or use may present an unreasonable risk. EPA has 
determined, however, that any domestic manufacture of the substance, 
use of the substance other than as a solvent or a cleaning and drying 
agent, or use in a consumer product may cause serious health effects. 
Based on this information, the PMN substance meets the concern criteria 
at Sec.  721.170(b)(3)(i).
    Recommended testing: EPA has determined that inhalation monitoring 
data, collected according to the EPA draft Inhalation Monitoring Data 
Collection Guidelines (located in the docket under docket ID number 
EPA-HQ-OPPT-2011-0941), would help characterize the human health 
effects of the PMN substance.
    CFR citation: 40 CFR 721.10434.

PMN Number P-99-1179

    Chemical name: Phenol, 2-(1-methyl-1-phenylethyl)-4-(1,1,3,3-
tetramethylbutyl)-.
    CAS number: 73936-80-8.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as an ultraviolet (UV) 
stabilizer for automotive coatings. Based on EcoSAR analysis of test 
data on analogous phenols, EPA predicts toxicity to aquatic organisms 
may occur at concentrations that exceed 1 ppb of the PMN substance in 
surface waters. As described in the PMN, releases of the substance are 
not expected to result in surface water concentrations that exceed 1 
ppb. Therefore, EPA has not determined that the proposed manufacturing, 
processing, or use of the substance may present an unreasonable risk. 
EPA has determined, however, that any use of the substance resulting in 
surface water concentrations exceeding 1 ppb may cause significant 
adverse environmental effects. Based on this information, the PMN 
substance meets the concern criteria at Sec.  721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a fish 
early-life stage toxicity test (OPPTS Test Guideline 850.1400); a 
daphnid chronic toxicity test (OPPTS Test Guideline 850.1300); and an 
algal toxicity test (OCSPP Test Guideline 850.4500) would help 
characterize the environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10435.

PMN Numbers P-99-1217 and P-99-1218

    Chemical name: Amine neutralized phosphated polyesters (generic).
    CAS number: Not available.
    Basis for action: The consolidated PMN states that the generic 
(non-confidential) use of the substances will be as pigment 
dispersants. Based on EcoSAR analysis of test data on analogous anionic 
surfactants, EPA predicts toxicity to aquatic organisms may occur as a 
result of releases of the PMN substances in quantities greater than the 
combined 50,000 kilograms (kgs) per year production volume stated in 
the PMN. At the annual production volume of 50,000 kgs stated in the 
consolidated PMN, there were no significant environmental releases. 
Therefore, EPA has not determined that the proposed manufacturing, 
processing, or use of the substances may present an unreasonable risk. 
EPA has determined, however, that exceeding an annual aggregate 
manufacturing and importation volume of 50,000 kgs may cause 
significant adverse environmental effects. Based on this information, 
the PMN substances meet the concern criteria at Sec.  
721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a fish 
early-life stage toxicity test (OPPTS Test Guideline 850.1400) and a 
daphnid chronic toxicity test (OPPTS Test Guideline 850.1300) would 
help characterize the environmental effects of the PMN substances.
    CFR citation: 40 CFR 721.10436.

PMN Numbers P-99-1280, P-99-1281, and P-99-1282

    Chemical name: Sulfonic acid, linear xylene alkylate, mono, sodium 
salts (generic).
    CAS number: Not available.
    Basis for action: The consolidated PMN states that the substances 
will be used as enhanced oil recovery surfactants. Based on EcoSAR 
analysis of test data on analogous anionic surfactants, EPA predicts 
toxicity to aquatic organisms may occur at concentrations that exceed 2 
ppb of the substances in surface waters for greater than 20 days per 
year. This 20-day criterion is derived from partial life cycle tests 
(daphnid chronic and fish early life stage tests) that typically range 
from 21 to 28 days in duration. EPA predicts toxicity to aquatic 
organisms may occur if releases of the PMN substances to surface water, 
from uses other than as described in the PMNs, exceed releases from the 
use described in the PMNs. For the use described in the PMNs, 
environmental releases did not exceed 2 ppb more than 20 days per year. 
Therefore, EPA has not determined that the proposed manufacturing, 
processing, or use of the PMN substances may present an unreasonable 
risk. EPA has determined, however, that any use of the substances other 
than as enhanced oil recovery surfactants may cause significant adverse 
environmental effects. Based on this information, the PMN substances 
meet the concern criteria at Sec.  721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a fish 
acute toxicity test, freshwater and marine (OPPTS Test Guideline 
850.1075); an aquatic invertebrate acute toxicity test, freshwater 
daphnids (OPPTS Test Guideline 850.1010); and an algal toxicity test 
(OCSPP Test Guideline 850.4500) would help characterize the 
environmental effects of the PMN substances.
    CFR citation: 40 CFR 721.10437.

PMN Number P-00-346

    Chemical name: Dialkyl hydroxybenzenealkanoic acid ester (generic).
    CAS number: Not available.
    Effective date of TSCA section 5(e) consent order: August 16, 2001.
    Basis for TSCA section 5(e) consent order: The PMN states that the 
generic (non-confidential) use of the substance will be as a petroleum 
additive. Based on test data on the PMN substance and SAR analysis of 
structurally similar substances, EPA identified concerns for liver and 
thyroid toxicity from dermal exposures. The consent order was issued 
under TSCA sections 5(e)(1)(A)(i), 5(e)(1)(A)(ii)(I), and 
5(e)(1)(A)(ii)(II), based on a finding that this substance may present 
an unreasonable risk of injury to human health, the substance may be 
produced in substantial quantities, and there may be significant (or 
substantial) human exposure to the substance. To protect against these 
risks, the consent order requires:
    1. Use of personal protective equipment including impervious gloves 
(when there is potential dermal exposure).
    2. Establishment and use of a hazard communication program.
    3. Submission of certain human health testing prior to exceeding 
the confidential production volume limit specified in the consent 
order.
    The SNUR designates as a ``significant new use'' the absence of 
these protective measures.

[[Page 58671]]

    Recommended testing: EPA has determined that the results of a 28-
day dermal toxicity test (The Organisation for Economic Co-operation 
and Development (OECD) Test Guideline 410) with emphasis on the thyroid 
(per OPPTS Test Guideline 870.3465) would help characterize the human 
health effects of the PMN substance. The PMN submitter has agreed not 
to exceed the confidential production volume limit specified in the 
consent order without performing this test.
    CFR citation: 40 CFR 721.10438.

PMN Number P-00-635

    Chemical name: 1,3-Dioxolan-2-one, 4-ethenyl.
    CAS number: 4427-96-7.
    Basis for action: The PMN states that the generic (non-
confidential) uses of the substance will be as a chemical intermediate 
and an industrial chemical additive. Based on test data on the PMN 
substance and SAR analysis of test data on analogous vinylene 
carbonate, EPA predicts acute toxicity, liver toxicity, kidney 
toxicity, developmental toxicity, immunotoxicity, and oncogenicity. For 
the uses described in the PMN, significant dermal exposures are not 
expected due to the use of impervious gloves. Therefore, EPA has not 
determined that the proposed manufacturing, processing, or use of the 
substance may present an unreasonable risk. EPA has determined, 
however, that any use of the substance without the use of impervious 
gloves where there is a potential for dermal exposures, or any use 
other than as described in the PMN may cause serious human health 
effects. Based on this information the PMN substance meets the concern 
criteria at Sec.  721.170(b)(1)(i)(C), (b)(3)(i), and (b)(3)(ii).
    Recommended testing: EPA has determined that no additional testing 
is recommended at this time as the health effects have been adequately 
characterized by the testing submitted on the PMN substance.
    CFR citation: 40 CFR 721.10439.

PMN Number P-00-1165

    Chemical name: Diphosphoric acid, polymers with ethoxylated reduced 
Me esters of reduced polymd, oxidized tetrafluoroethylene.
    CAS number: 200013-65-6.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as a surface active agent. 
Based on analogous high molecular weight polymers, EPA identified 
concerns from inhalation exposures. For the industrial uses described 
in the PMN, worker inhalation exposures are not expected as the 
substance is not applied by a method that generates a vapor, mist, or 
spray. Therefore, EPA has not determined that the proposed 
manufacturing, processing, or use may present an unreasonable risk. EPA 
has determined, however, that any use of the substance in consumer 
products, or any use involving an application method that generates a 
vapor, mist, or spray may cause serious health effects. Based on the 
information, the PMN substance meets the criteria at 721.170(b)(3)(ii).
    Recommended testing: EPA has determined that the results of an 
acute inhalation toxicity test (OPPTS Test Guideline 870.1300) would 
help characterize the human health effects of the PMN substance.
    CFR citation: 40 CFR 721.10440.

PMN Numbers P-01-382 and P-01-383

    Chemical names: (P-01-382) 1, 2-Benzenedicarboxylic acid, di-
C7-14-branched and linear alkyl esters and (P-01-383) 1,2-
Benzenedicarboxylic acid, di-C6-14-branched and linear alkyl 
esters.
    CAS numbers: (P-01-382) 309934-68-7 and (P-01-383) 309934-69-8.
    Basis for action: The consolidated PMN states that the substances 
will be used as plasticizers for flexible poly-vinyl chloride. Based on 
SAR analysis of the expected ester hydrolysis product of the PMNs, EPA 
identified concerns for liver, developmental, and reproductive 
toxicity; and oncogenicity. For the use described in the PMNs, neither 
significant worker exposures nor general population exposures are 
expected. Therefore, EPA has not determined that the proposed 
manufacturing, processing, or use of the substances may present an 
unreasonable risk. EPA has determined, however, that any use of the 
substances in children's toys (e.g., pacifiers, rattles, and teethers) 
may cause serious health effects. Based on this information, the PMN 
substances meet the criteria at Sec.  721.170(b)(1)(i)(C) and 
(b)(3)(ii).
    Recommended testing: EPA has determined that the results of an 
acute oral toxicity test (OECD Test Guideline 401 or 420); an acute 
dermal toxicity test (OECD Test Guideline 402); an acute inhalation 
toxicity test (OECD Test Guideline 403); a repeated dose 28-day oral 
toxicity test in rodents (OECD Test Guideline 407); a 28-day dermal 
toxicity test (OECD Test Guideline 410); a 28-day subacute inhalation 
toxicity test (OECD Test Guideline 412); a prenatal developmental 
toxicity test (OECD Test Guideline 414); a 1-generation reproduction 
test (OECD Test Guideline 415); a reproduction and fertility effects 
test (OECD Test Guideline 416); a reproduction/development toxicity 
screening test (OECD Test Guideline 421); a combined repeated dose 
toxicity test with the reproduction/development toxicity screening test 
(OECD Test Guideline 422); a bacterial reverse mutation test (OECD Test 
Guideline 471); an in vitro mammalian chromosome aberration test (OECD 
Test Guideline 473); a mammalian erythrocyte micronucleus test (OECD 
Test Guideline 474); and a mammalian bone marrow chromosomal aberration 
test (OECD Test Guideline 475) would help characterize the human health 
effects of the PMN substances.
    CFR citations: 40 CFR 721.10441 (P-01-382) and 40 CFR 721.10442 (P-
01-383).

PMN Number P-01-470

    Chemical name: Ethoxylated alkylphenol sulfate, ammonium salt 
(generic).
    CAS number: Not available.
    Effective date of TSCA section 5(e) consent order: August 26, 2002.
    Basis for TSCA section 5(e) consent order: The PMN states that the 
substance will be used as a dispersant for carbon black and organic 
pigments. Based on test data on the PMN substance, and EcoSAR analysis 
of test data on analogous ethoxylated anionic surfactants, EPA predicts 
environmental toxicity that varies depending on the average number of 
moles of ethoxylate. As the number of ethoxylate decreases, the aquatic 
toxicity of the substance increases. For this PMN substance, the 
average number of moles may vary. Based on submitted test data on the 
PMN--with an average number of 16.4 moles of ethoxylate--EPA predicts 
toxicity to aquatic organisms may occur at concentrations that exceed 
200 ppb of the PMN substance in surface waters. When the average number 
of moles of ethoxylate is less than or equal to 10, EPA expects 
toxicity to aquatic organisms may occur at concentrations that exceed 
60 ppb of the substance in surface waters. The consent order was issued 
under TSCA sections 5(e)(1)(A)(i), 5(e)(1)(A)(ii)(I), and 
5(e)(1)(A)(ii)(II), based on a finding that the substance may present 
an unreasonable risk of injury to the environment, may be produced in 
substantial quantities, and may be reasonably anticipated to enter the 
environment in substantial quantities. To protect against these risks, 
the consent order prohibits the company from manufacturing or importing 
the PMN substance unless either: The mean number of moles of the ethoxy 
group is greater than or equal to 10, or the

[[Page 58672]]

average number molecular weight is greater than 950 daltons. The SNUR 
designates as a ``significant new use'' the absence of these protective 
measures.
    Recommended testing: EPA has determined that the results of a fish 
acute toxicity test, freshwater and marine (OPPTS Test Guideline 
850.1075); an aquatic invertebrate acute toxicity test, freshwater 
daphnids (OPPTS Test Guideline 850.1010); and an algal toxicity test 
(OCSPP Test Guideline 850.4500) would help characterize environmental 
effects of the PMN substance. Testing should be conducted on the PMN 
substance with less than 10 moles of ethoxylate, or an average number 
molecular weight of less than 950 daltons. The consent order does not 
require the submission of the aforementioned testing at any specified 
time or production volume. However, the order's restrictions on 
manufacture, import, processing, distribution in commerce, use, and 
disposal of the PMN will remain in effect until the consent order is 
modified or revoked by EPA based on submission of that or other 
relevant information.
    CFR citation: 40 CFR 721.10443.

PMN Number P-01-499 and P-01-500

    Chemical name: (P-01-499) Propanol, mercapto- and (P-01-500) 2-
Propen-1-ol, reaction products with hydrogen sulfide, distn. residues.
    CAS number: (P-01-499) 63947-56-8 and (P-01-500) 374078-75-8.
    Basis for action: The PMNs state that the substances will be used 
as chemical intermediates. Based on SAR analysis of test data on 
structurally similar 3- mercaptopropanol, EPA identified concerns for 
developmental and maternal effects from dermal exposures to the PMN 
substances. In addition, based on test data on P-01-499 and EcoSAR 
analysis of analogous thiols, EPA predicts toxicity to aquatic 
organisms may occur at surface water concentrations that exceed 11 ppb 
for P-01-499 and 1 ppb for P-01-500. For the chemical intermediate use 
described in the PMNs, significant worker exposures are not expected 
due to the use of impervious dermal protection, and the substances are 
not released to surface water. Therefore, EPA has not determined that 
the proposed manufacturing, processing, or use of the substances may 
present an unreasonable risk. EPA has determined, however, that any use 
of the substances without impervious dermal protection where there is a 
potential for dermal exposures, or any use of the substances resulting 
in surface water concentrations exceeding 11 ppb (P-01-499) or 1 ppb 
(P-01-500) may cause serious health effects and significant adverse 
environmental effects. Based on this information, the PMN substances 
meet the concern criteria at Sec.  721.170(b)(3)(ii), (b)(4)(i), and 
(b)(4)(ii).
    Recommended testing: EPA has determined that the results of an 
aquatic invertebrate acute toxicity test, freshwater daphnids (OPPTS 
Test Guideline 850.1010) on P-01-500 would help to characterize the 
environmental effects of the PMN substances.
    CFR citation: 40 CFR 721.10444 (P-01-499) and 40 CFR 721.10445 (P-
01-500).

PMN Number P-01-762

    Chemical name: 1,9-Cyclohexadecadiene.
    CAS number: 4277-06-9.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as open, non-dispersive use 
with limited employee exposure. Based on test data on the PMN 
substance, EPA identified concerns for dermal sensitization and 
irritation. In addition, based on test data on the PMN substance and 
EcoSAR analysis of test data on analogous neutral organic chemicals, 
EPA predicts toxicity to aquatic organisms at concentrations that 
exceed 1 ppb of the PMN substance in surface waters. As described in 
the PMN, significant dermal exposures are not expected due to the use 
of impervious gloves, and releases of the substance to surface waters 
are not expected in concentrations that exceed 1 ppb. Therefore, EPA 
has not determined that manufacturing, processing, and use of the 
substance may present an unreasonable risk. EPA has determined, 
however, that use of the substance without impervious protective 
equipment where there is a potential for dermal exposures, or any use 
of the substance resulting in surface water concentrations exceeding 1 
ppb may cause serious health effects and significant adverse 
environmental effects. Based on this information, the PMN substance 
meets the concern criteria in Sec.  721.170(b)(3)(i), (b)(4)(i), and 
(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a fish 
acute toxicity test, freshwater and marine (OPPTS Test Guideline 
850.1075); an aquatic invertebrate acute toxicity test, freshwater 
daphnids (OPPTS Test Guideline 850.1010); and an algal toxicity test 
(OCSPP Test Guideline 850.4500) would help characterize the 
environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10446.

PMN Number P-01-829

    Chemical name: 17-Oxabicyclo[14.1.0]heptadec-8-ene.
    CAS number: 34748-97-5.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as open, non-dispersive with 
limited employee exposure. Based on test data on the PMN substance, EPA 
identified concerns for dermal sensitization, respiratory 
sensitization, mutagenicity, developmental toxicity, male reproductive 
toxicity, liver toxicity, and kidney toxicity. In addition, based on 
test data on the PMN substance and EcoSAR analysis of test data on 
analogous epoxides, EPA predicts toxicity to aquatic organisms at 
concentrations that exceed 1 ppb of the substance in surface waters. As 
described in the PMN, significant exposures are not expected due to the 
use of protective dermal and respiratory equipment, and the substance 
is not released to surface waters in concentrations that exceed 1 ppb. 
Therefore, EPA has not determined that the proposed manufacturing, 
processing, or use of the substance may present an unreasonable risk. 
EPA has determined, however, that any use of the substance without 
impervious dermal and adequate respiratory protection where there is a 
potential for exposures, or any use of the substance resulting in 
surface water concentrations exceeding 1 ppb may cause serious health 
effects and significant adverse environmental effects. Based on this 
information the PMN substance meets the concern criteria at Sec.  
721.170(b)(3)(i), (b)(4)(i), and (b)(4)(ii).
    Recommended testing: EPA has determined that the results of a fish 
acute toxicity test, freshwater and marine (OPPTS Test Guideline 
850.1075); an aquatic invertebrate acute toxicity test, freshwater 
daphnids (OPPTS Test Guideline 850.1010); and an algal toxicity test 
(OCSPP Test Guideline 850.4500) would help characterize the 
environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10447.

PMN Number P-02-120

    Chemical name: Acetic acid, hydroxymethoxy-, methyl ester, reaction 
products with substituted alkylamine (generic).
    CAS number: Not available.
    Effective date of TSCA section 5(e) consent order: September 12, 
2003.

[[Page 58673]]

    Basis for TSCA section 5(e) consent order: The PMN states that the 
generic (non-confidential) use of the substance will be as an 
emulsifier. Based on EcoSAR analysis of test data on analogous 
aliphatic amines, EPA predicts toxicity to aquatic organisms may occur 
when the average number molecular weight is below 850 daltons. The 
order was issued under TSCA sections 5(e)(1)(A)(i), 5(e)(1)(A)(ii)(I) 
and 5(e)(1)(A)(ii)(II), based on a finding that this substance may 
reasonably be anticipated to enter the environment in substantial 
quantities and may present an unreasonable risk of injury to the 
environment. The consent order for this substance prohibits 
manufacturing or importing of the PMN substance unless the average 
number molecular weight is greater than or equal to 850 daltons. The 
SNUR designates as a ``significant new use'' the absence of these 
protective measures.
    Recommended testing: EPA has determined that the results of a fish 
acute toxicity test, freshwater and marine (OPPTS Test Guideline 
850.1075); an aquatic invertebrate acute toxicity test, freshwater 
daphnids (OPPTS Test Guideline 850.1010); and an algal toxicity test 
(OCSPP Test Guideline 850.4500), on the PMN substance where the average 
number molecular weight is less than 850 daltons would help 
characterize possible environmental effects of the substance. The order 
does not require submission of the aforementioned information at any 
specified time or production volume. However, the order's restrictions 
on manufacture, import, processing, distribution in commerce, use, and 
disposal of the PMN substance will remain in effect until the order is 
modified or revoked by EPA based on submission of that or other 
relevant information.
    CFR citation: 40 CFR 721.10448.

PMN Number P-02-172

    Chemical name: Aromatic polyester polyol (generic).
    CAS number: Not available.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as an adhesive component. 
Based on EcoSAR analysis of test data on analogous esters, EPA predicts 
toxicity to aquatic organisms may occur at concentrations that exceed 
40 ppb of the PMN substance in surface waters. As described in the PMN, 
EPA does not expect releases to surface waters to exceed 40 ppb. 
Therefore, EPA has not determined that the proposed manufacturing, 
processing, or use of the substance may present an unreasonable risk. 
EPA has, however, determined that any use of the substance resulting in 
surface water concentrations exceeding 40 ppb may cause significant 
adverse environmental effects. Based on this information, the substance 
meets the concern criteria at Sec.  721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a fish 
acute toxicity test, freshwater and marine (OPPTS Test Guideline 
850.1075); an aquatic invertebrate acute toxicity test, freshwater 
daphnids (OPPTS Test Guideline 850.1010); and an algal toxicity test 
(OCSPP Test Guideline 850.4500) would help characterize the 
environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10449.

PMN Number P-02-285

    Chemical name: Oxirane, 2-[[3-(trimethoxysilyl)propoxy]methyl]-, 
reaction products with wollastonite (Ca(SiO3)).
    CAS number: 100402-91-3.
    Effective date of TSCA section 5(e) consent order: October 14, 
2002.
    Basis for TSCA section 5(e) consent order: The PMN states that the 
substance will be used as functional filler for polymer systems. Based 
on SAR analysis of analogous respirable, poorly soluble particulates, 
EPA identified concerns for lung toxicity based on lung overload, and 
concern for carcinogenicity based on test data on the starting raw 
material--wollastonite. The consent order was issued under TSCA 
sections 5(e)(1)(A)(i) and 5(e)(1)(A)(ii)(I), based on a finding that 
this substance may present an unreasonable risk of injury to human 
health. To protect against this exposure and risk, the consent order 
requires the company to manufacture and process the PMN substance with 
an average aspect ratio of no greater than 5, and no more than 15 
percent of the PMN substance shall have an aspect ratio greater than 
10. The SNUR designates as a ``significant new use'' the absence of 
these protective measures.
    Recommended testing: EPA had determined that the results of a 90-
day inhalation toxicity test (OPPTS Test Guideline 870.3465) with a 60-
day holding period and a carcinogenicity test (OPPTS Test Guideline 
870.4200) would help characterize the human health effects of the PMN 
substance. These tests should be conducted on the PMN substance with an 
average aspect ratio of greater than 5, and more than 15 percent of the 
PMN substance with an aspect ratio of greater than 10. The order does 
not require submission of the aforementioned information at any 
specified time or production volume. However, the order's restrictions 
on manufacture, import, processing, distribution in commerce, use, and 
disposal of the PMN substance will remain in effect until the order is 
modified or revoked by EPA based on submission of that or other 
relevant information.
    CFR citation: 40 CFR 721.10450.

PMN Number P-02-436

    Chemical name: Alkyd amide polyol (generic).
    CAS number: Not available.
    Basis for action: The PMN states that the substance will be used as 
an intermediate for polyurethane polymers. Based on EcoSAR analysis of 
test data on analogous nonionic surfactants, EPA predicts toxicity to 
aquatic organisms may occur at concentrations that exceed 3 ppb of the 
PMN substance in surface waters. As described in the PMN, the substance 
is not released to surface waters. Therefore, EPA has not determined 
that the proposed manufacturing, processing, or use of the substance 
may present an unreasonable risk. EPA has determined, however, that any 
use of the substance resulting in surface water concentrations 
exceeding 3 ppb may cause significant adverse environmental effects. 
Based on this information, the PMN substance meets the concern criteria 
at Sec.  721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a fish 
acute toxicity test, freshwater and marine (OPPTS Test Guideline 
850.1075); an aquatic invertebrate acute toxicity test, freshwater 
daphnids (OPPTS Test Guideline 850.1010); and an algal toxicity test 
(OCSPP Test Guideline 850.4500) would help characterize the 
environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10451.

PMN Number P-02-659

    Chemical name: 9-Octadecenoic acid (9Z)-, 1,1'-(dimethylstannylene) 
ester.
    CAS number: 3865-34-7.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as a catalyst. Based on 
EcoSAR analysis of test data on analogous nonionic surfactants, EPA 
predicts toxicity to aquatic organisms may occur at concentrations that 
exceed 10 ppb of the substance in surface waters. As described in the 
PMN, the substance is not released to surface waters. Therefore, EPA 
has not determined that the proposed manufacturing, processing, or use 
of the substance may present an unreasonable risk. EPA has determined, 
however, that any use of the substance resulting in surface water 
concentrations exceeding

[[Page 58674]]

10 ppb may cause significant adverse environmental effects. Based on 
this information, the PMN substance meets the concern criteria at Sec.  
721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a fish 
acute toxicity test, freshwater and marine (OPPTS Test Guideline 
850.1075); an aquatic invertebrate acute toxicity test, freshwater 
daphnids (OPPTS Test Guideline 850.1010); and an algal toxicity test 
(OCSPP Test Guideline 850.4500) would help characterize the 
environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10452.

PMN Number P-02-796

    Chemical name: Polyglycerin alkyl ether (generic).
    CAS number: Not available.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as a lubricant additive. 
Based on test data on the PMN substance and EcoSAR analysis of test 
data on analogous nonionic surfactants, EPA predicts toxicity to 
aquatic organisms may occur at concentrations that exceed 3 ppb of the 
substance in surface waters for greater than 20 days per year. This 20-
day criterion is derived from partial life cycle tests (daphnid chronic 
and fish early life stage tests) that typically range from 21 to 28 
days in duration. EPA predicts toxicity to aquatic organisms may occur 
if releases of the PMN substance to surface water, from uses other than 
as described in the PMN, exceed releases from the use described in the 
PMN. For the use described in the PMN, environmental releases did not 
exceed 3 ppb more than 20 days per year. Therefore, EPA has not 
determined that the proposed manufacturing, processing, or use of the 
substance may present an unreasonable risk. EPA has determined, 
however, that any use of the substance other than as described in the 
PMN may cause significant adverse environmental effects. Based on this 
information, the PMN substance meets the concern criteria at Sec.  
721.170(b)(4)(i) and (b)(4)(ii).
    Recommended testing: EPA has determined that the results of a ready 
biodegradability test (OPPTS Test Guideline 835.3110) would help 
characterize the environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10453.

PMN Number P-02-828

    Chemical name: Propoxylated ethoxylated alkylamine (generic).
    CAS number: Not available.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as a concrete admixture. 
Based on EcoSAR analysis of analogous cationic surfactants, EPA 
predicts toxicity to aquatic organisms may occur at concentrations that 
exceed 80 ppb of the PMN substance in surface waters. As described in 
the PMN, the substance is not released to surface waters in 
concentrations that exceed 80 ppb. Therefore, EPA has not determined 
that the proposed manufacturing, processing, or use of the substance 
may present an unreasonable risk. EPA has determined, however, that any 
use of the substance resulting in surface water concentrations 
exceeding 80 ppb may cause significant adverse environmental effects. 
Based on this information, the PMN substance meets the concern criteria 
at Sec.  721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a ready 
biodegradability test (OPPTS Test Guideline 835.3110); fish acute 
toxicity test, freshwater and marine (OPPTS Test Guideline 850.1075); 
an aquatic invertebrate acute toxicity test, freshwater daphnids (OPPTS 
Test Guideline 850.1010); and an algal toxicity test (OCSPP Test 
Guideline 850.4500) would help characterize the environmental effects 
of the PMN substance.
    CFR citation: 40 CFR 721.10454.

PMN Number P-03-61

    Chemical name: Oxirane, 2,2',2''-[ethylidynetris(4,1-
phenyleneoxymethylene)]tris-.
    CAS number: 87093-13-8.
    Basis for action: The PMN states that the substance will be used as 
a high-density cross-linked polymer in resins, composites, and 
adhesives. Based on test data on the PMN substance and SAR analysis of 
test data on analogous epoxides, EPA identified concerns for cancer, 
reproductive toxicity in males, developmental toxicity, and 
sensitization to lungs from worker and consumer inhalation exposures. 
As described in the PMN, significant occupational and consumer 
inhalation exposures are not expected, as the substance is not spray 
applied. Therefore, EPA has not determined that the proposed 
manufacturing, processing, or use of the substance may present an 
unreasonable risk. EPA has determined, however, that any use of the 
substance involving an application method that generates a mist, vapor, 
or aerosol may cause serious health effects. Based on this information, 
the PMN substance meets the concern criteria at Sec.  
721.170(b)(1)(i)(C), (b)(3)(i), and (b)(3)(ii).
    Recommended testing: EPA has determined that the results of a 90-
day inhalation toxicity test (OPPTS Test Guideline 870.3465) in rats 
would help characterize the human health effects of the PMN substance.
    CFR citation: 40 CFR 721.10455.

PMN Number P-03-104

    Chemical name: Tristyryl phenol alkoxylate salt (generic).
    CAS number: Not available.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as an agricultural inert. 
Based on EcoSAR analysis of test data on analogous cationic and anionic 
surfactants, EPA predicts toxicity to aquatic organisms may occur at 
concentrations that exceed 2 ppb of the substance in surface waters for 
greater than 20 days per year. This 20-day criterion is derived from 
partial life cycle tests (daphnid chronic and fish early life stage 
tests) that typically range from 21 to 28 days in duration. EPA 
predicts toxicity to aquatic organisms may occur if releases of the PMN 
substance to surface water, from uses other than as described in the 
PMN, exceed releases from the use described in the PMN. For the use 
described in the PMN, environmental releases did not exceed 2 ppb more 
than 20 days per year. Therefore, EPA has not determined that the 
proposed manufacturing, processing, or use of the substance may present 
an unreasonable risk. EPA has determined, however, that any use of the 
substance other than as described in the PMN may cause significant 
adverse environmental effects. Based on this information, the PMN 
substance meets the concern criteria at Sec.  721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a fish 
acute toxicity test, freshwater and marine (OPPTS Test Guideline 
850.1075); an aquatic invertebrate acute toxicity test, freshwater 
daphnids (OPPTS Test Guideline 850.1010); and an algal toxicity test 
(OCSPP Test Guideline 850.4500) would help characterize the 
environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10456.

PMN Number P-03-154

    Chemical name: 1,2-Benzenedicarboxylic acid, mixed esters with 
benzyl alc., cyclohexanol, 2-ethyl-1-hexanol, fumaric acid and 
propylene glycol.
    CAS number: 464920-01-2.
    Basis for action: The PMN states that the substance will be used as 
a monomer combined with styrene and unsaturated polyester resins. Based 
on

[[Page 58675]]

EcoSAR analysis of test data on analogous acrylates and esters, EPA 
predicts toxicity to aquatic organisms may occur at concentrations that 
exceed 1 ppb of the substance in surface waters. As described in the 
PMN, the substance is not released to surface waters. Therefore, EPA 
has not determined that the proposed manufacturing, processing, or use 
of the substance may present an unreasonable risk to the environment. 
EPA has determined, however, that any use of the substance resulting in 
surface water concentrations exceeding 1 ppb may cause significant 
adverse environmental effects. Based on this information, the PMN 
substance meets the concern criteria at Sec.  721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a ready 
biodegradability test (OPPTS Test Guideline 835.3110); a fish acute 
toxicity test, freshwater and marine (OPPTS Test Guideline 850.1075); 
an aquatic invertebrate acute toxicity test, freshwater daphnids (OPPTS 
Test Guideline 850.1010); and an algal toxicity test (OCSPP Test 
Guideline 850.4500) would help characterize the environmental effects 
of the PMN substance.
    CFR citation: 40 CFR 721.10457.

PMN Number P-03-238

    Chemical name: Acrylate of hydroxyimide (generic).
    CAS number: Not available.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be in adhesives. Based on test 
data on the PMN substance and SAR analysis of test data on analogous 
acrylates, EPA identified concerns for developmental toxicity and 
sensitization from inhalation exposure to the PMN substance. In 
addition, based on EcoSAR analysis of test data on analogous acrylates, 
EPA expects toxicity to aquatic organisms may occur at concentrations 
that exceed 20 ppb of the PMN substance in surface waters. As described 
in the PMN, significant worker exposures are not expected as the 
substance is used in the liquid form, and the substance is not released 
to surface waters. Therefore, EPA has not determined that the proposed 
manufacturing, processing, or use of the substance may present an 
unreasonable risk. EPA has determined, however, that any manufacturing, 
processing, or use of the substance in a solid form, or any use 
resulting in surface water concentrations exceeding 20 ppb may cause 
serious health effects and significant adverse environmental effects. 
Based on this information the PMN substance meets the concern criteria 
at Sec.  721.170(b)(3)(i), (b)(3)(ii), and (b)(4)(ii).
    Recommended testing: EPA has determined that the results of a 
prenatal developmental toxicity test (OPPTS Test Guideline 870.3700) in 
rats; a fish acute toxicity test, freshwater and marine (OPPTS Test 
Guideline 850.1075); an aquatic invertebrate acute toxicity test, 
freshwater daphnids (OPPTS Test Guideline 850.1010); and an algal 
toxicity test (OCSPP Test Guideline 850.4500) would help to 
characterize the human health and environmental effects of the 
substance.
    CFR citation: 40 CFR 721.10458.

PMN Number P-03-282

    Chemical name: Amino-substituted carbopolycycle (generic).
    CAS number: Not available.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as a raw material. Based on 
test data on the PMN substance and SAR analysis of test data on 
analogous alpha-naphthylamine, aniline, aromatic amine, and 
naphthalene, EPA identified concerns for mutagenicity, oncogenicity, 
sensitization, developmental toxicity, blood effects, neurotoxicity, 
liver effects, and cancer to workers exposed to the PMN substance. As 
described in the PMN, significant worker exposures are not expected due 
to the use of adequate personal protective equipment. Therefore, EPA 
has not determined that the proposed manufacturing, processing, or use 
of the substance may present an unreasonable risk. EPA has determined, 
however, that any use of the substance without the use of impervious 
gloves where there is potential for dermal exposure, use of the 
substance without the use of a National Institute for Occupational 
Safety and Health (NIOSH)-certified respirator with an assigned 
protection factor (APF) of at least 50 where there is potential 
inhalation exposure, domestic manufacture, or use of the substance 
other than as described in the PMN may cause serious health effects. 
Based on this information, the PMN substance meets the concern criteria 
at Sec.  721.170(b)(1)(i)(C), (b)(3)(i), and (b)(3)(ii).
    Recommended testing: EPA has determined that inhalation monitoring 
data, collected according to the EPA draft Inhalation Monitoring Data 
Collection Guidelines (located in the docket under docket ID number 
EPA-HQ-OPPT-2011-0941), would help characterize the human health 
effects of the PMN substance.
    CFR citation: 40 CFR 721.10459.

PMN Number P-03-307

    Chemical name: Azo nickel complex (generic).
    CAS number: Not available.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as a colorant. EPA 
identified concerns for oncogenicity, pulmonary sensitization, 
immunotoxicity, developmental toxicity, and neurotoxicity for released 
nickel. In addition, test data for nickel sulfate hexahydrate has shown 
effects on the brain, kidney, liver, testes, thymus, and spleen. For 
the use described in the PMN, worker inhalation exposures from the 
liquid form of the PMN are not expected. Therefore, EPA has not 
determined that manufacturing, processing, and use of the substance may 
present an unreasonable risk. EPA has determined, however, that any use 
of the substance other than as described in the PMN, or any use of the 
substance as a powder, may cause serious health effects. Based on this 
information, the PMN substance meets the concern criteria at Sec.  
721.170(b)(1)(i)(C) and (b)(3)(ii).
    Recommended testing: EPA has determined that the results of a 90-
day inhalation toxicity test (OPPTS Test Guideline 870.3465); a 
reproduction and fertility effects test (OPPTS Test Guideline 
870.3800); and a carcinogenicity study (OPPTS Test Guideline 870.4200) 
would help to characterize the human health effects of the PMN 
substance.
    CFR citation: 40 CFR 721.10460.

PMN Number P-03-325

    Chemical name: Oxazolidine, 3,3'-methylenebis[5-methyl-.
    CAS number: 66204-44-2.
    Basis for action: The PMN states that the substance will be used as 
a metalworking fluid. Based on test data on the PMN substance, EPA 
identified concerns for systemic toxicity and severe skin and eye 
irritation. In addition, based on test data on the PMN substance and 
EcoSAR analysis of test data on analogous aliphatic amines, EPA 
predicts toxicity to aquatic organisms may occur at surface water 
concentrations that exceed 40 ppb of the substance in saltwater, and 
100 ppb of the substance in freshwater. For the use described in the 
PMN, worker exposures are not expected as the substance is used in an 
enclosed system, and the substance is not released to surface waters. 
Therefore, EPA has not determined that manufacturing, processing, and 
use of the substance may present an unreasonable risk. EPA has 
determined, however, that use of the

[[Page 58676]]

substance other than as a metalworking fluid, or any use of the 
substance resulting in surface water concentrations exceeding the 
freshwater and saltwater concentrations of concern may cause serious 
health effects and significant adverse environmental effects. Based on 
this information the PMN substance meets the concern criteria at Sec.  
721.170(b)(3)(i), (b)(4)(i), and (b)(4)(ii).
    Recommended testing: EPA has determined that the no additional 
testing is recommended at this time as the human health and 
environmental effects have been adequately characterized by the testing 
submitted on the PMN substance.
    CFR citation: 40 CFR 721.10461.

PMN Number P-03-354

    Chemical name: 1-Penten-3-one, 1-(4-chlorophenyl)-4,4-dimethyl-.
    CAS number: 1577-03-3.
    Basis for action: The PMN states that the substance will be used as 
an intermediate. Based on EcoSAR analysis of test data on analogous 
vinyl ketones, EPA predicts toxicity to aquatic organisms may occur at 
concentrations that exceed 30 ppb of the substance in surface waters. 
For the use described in the PMN, EPA does not expect releases of the 
substance to surface waters in concentrations that exceed 30 ppb. 
Therefore, EPA has not determined that the proposed manufacturing, 
processing, or use of the substance may present an unreasonable risk. 
However, EPA has determined that any use of the substance other than as 
an intermediate, or any use of the substance resulting in surface water 
concentrations exceeding 30 ppb may cause significant adverse 
environmental effects. Based on this information, the substance meets 
the concern criteria at Sec.  721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a 
porous pot test (OPPTS Test Guideline 835.3220); a fish early life-
stage toxicity test (OPPTS Test Guideline 850.1400); a daphnid chronic 
toxicity test (OPPTS Test Guideline 850.1300); and an algal toxicity 
test (OCSPP Test Guideline 850.4500) would help characterize the 
environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10462.

PMN Number P-03-388

    Chemical name: Fatty acid amides (generic).
    CAS number: Not available.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as a paint and coating 
additive. Based on EcoSAR analysis of test data on analogous aliphatic 
amines, EPA predicts toxicity to aquatic organisms may occur at 
concentrations that exceed 1 ppb of the substance in surface waters for 
greater than 20 days per year. This 20-day criterion is derived from 
partial life cycle tests (daphnid chronic and fish early life stage 
tests) that typically range from 21 to 28 days in duration. EPA 
predicts toxicity to aquatic organisms may occur if releases of the PMN 
substance to surface water, from uses other than as described in the 
PMN, exceed releases from the use described in the PMN. For the use 
described in the PMN, environmental releases did not exceed 1 ppb more 
than 20 days per year. Therefore, EPA has not determined that the 
proposed manufacturing, processing, or use of the substance may present 
an unreasonable risk. EPA has determined, however, that use of the 
substance other than as described in the PMN may cause significant 
adverse environmental effects. Based on this information the PMN 
substance meets the concern criteria at Sec.  721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a fish 
acute toxicity test, freshwater and marine (OPPTS Test Guideline 
850.1075); an aquatic invertebrate acute toxicity test, freshwater 
daphnids (OPPTS Test Guideline 850.1010); and an algal toxicity test 
(OCSPP Test Guideline 850.4500) would help to characterize the 
environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10463.

PMN Number P-03-461

    Chemical name: Fatty acid, reaction products with alkanolamine 
(generic).
    CAS number: Not available.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as a petroleum additive. 
Based on EcoSAR analysis of test data on analogous aliphatic amines, 
EPA predicts toxicity to aquatic organisms may occur at concentrations 
that exceed 6 ppb of the substance in surface waters for greater than 
20 days per year. This 20-day criterion is derived from partial life 
cycle tests (daphnid chronic and fish early life stage tests) that 
typically range from 21 to 28 days in duration. EPA predicts toxicity 
to aquatic organisms may occur if releases of the PMN substance to 
surface water, from uses other than as described in the PMN, exceed 
releases from the use described in the PMN. For the use described in 
the PMN, environmental releases did not exceed 6 ppb more than 20 days 
per year. Therefore, EPA has not determined that the proposed 
manufacturing, processing, or use of the substance may present an 
unreasonable risk. EPA has determined, however, that use of the 
substance other than as described in the PMN may cause significant 
adverse environmental effects. Based on this information, the PMN 
substance meets the concern criteria at Sec.  721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a fish 
acute toxicity test, freshwater and marine (OPPTS Test Guideline 
850.1075); an aquatic invertebrate acute toxicity test, freshwater 
daphnids (OPPTS Test Guideline 850.1010); and an algal toxicity test 
(OCSPP Test Guideline 850.4500) would help characterize the 
environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10464.

PMN Numbers P-03-561, P-03-563, P-03-564, P-03-565, and P-03-566

    Chemical names: (P-03-561) 2-Propenoic acid, 2-methyl-, 3-
hydroxytricyclo[3.3.1.13,7]dec-1-yl ester; (P-03-563) 2-Propenoic acid, 
2-methyl-, 2-ethyltricyclo[3.3.1.13,7]dec-2-yl ester; (P-03-564) 2-
Propenoic acid, 3-hydroxytricyclo [3.3.1.13,7] dec-1-yl ester; (P-03-
565) 2-Propenoic acid, 2-methyltricyclo[3.3.1.13,7]dec-2-yl ester; and 
(P-03-566) 2-Propenoic acid, 2-ethyltricyclo[3.3.1.13,7]dec-2-yl ester.
    CAS numbers: (P-03-561) 115372-36-6; (P-03-563) 209982-56-9; (P-03-
564) 216581-76-9; (P-03-565) 249562-06-9; and (P-03-566) 303186-14-3.
    Basis for action: The consolidated PMN states that the generic 
(non-confidential) use of the substances will be as monomers. Based on 
test data on the PMN substances and SAR analysis of test data on 
analogous acrylates and methacrylates, EPA identified concerns for 
systemic toxicity and pulmonary sensitization. In addition, based on 
EcoSAR analysis of test data on analogous acrylates, EPA predicts 
toxicity to aquatic organisms may occur at concentrations that exceed 3 
ppb of the PMN substances in surface waters. For the uses described in 
the PMN, significant worker exposures are not expected due to the use 
of impervious gloves, protective clothing, eye protection, and adequate 
warnings in the MSDS; and the substance is not released to surface 
waters. Therefore, EPA has not determined that the proposed 
manufacturing, processing, or use of the substances may present an 
unreasonable risk. EPA has determined, however, that any use of the 
substance without worker protection where there is a potential for 
dermal or inhalation exposure, or any use of the substance resulting in 
surface water

[[Page 58677]]

concentrations exceeding 3 ppb may cause serious health effects and 
significant adverse environmental effects. Based on this information 
the PMN substances meet the concern criteria at Sec.  721.170(b)(3)(i), 
(b)(3)(ii), and (b)(4)(ii).
    Recommended testing: EPA has determined that the results of a fish 
acute toxicity test, freshwater and marine (OPPTS Test Guideline 
850.1075); a fish acute toxicity test mitigated by humic acid (OPPTS 
Test Guideline 850.1085); an aquatic invertebrate acute toxicity test, 
freshwater daphnids (OPPTS Test Guideline 850.1010); and an algal 
toxicity test (OCSPP Test Guideline 850.4500) would help to 
characterize the environmental effects of the PMN substances.
    CFR citations: 40 CFR 721.10465 (P-03-561); 40 CFR 721.10466; (P-
03-563); 40 CFR 721.10467 (P-03-564); 40 CFR 721.10468 (P-03-565); and 
40 CFR 721.10469 (P-03-566).

PMN Number P-03-567

    Chemical name: Phosphonium, tetrabutyl-, 1,1,2,2,3,3,4,4,4-
nonafluoro-1-butanesulfonate (1:1).
    CAS number: 220689-12-3.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as a polymer additive. Based 
on test data on the PMN substance, EPA identified concerns for systemic 
toxicity and neurotoxicity from inhalation exposures. In addition, EPA 
identified concern for potential degradation products, byproducts, 
unreacted material, and low molecular weight species. The PMN substance 
is a derivative of perfluorobutanesulfonate (PFBS) and may degrade to 
form PFBS. Further, concerns for the substance are based on analogous 
perfluorooctanesulfonate (PFOS). For the use described in the PMN, 
significant exposures and environmental releases are not expected. 
Therefore, EPA has not determined that the proposed manufacturing, 
processing, or use may present an unreasonable risk. EPA has 
determined, however, that any use of the substance other than as 
described in the PMN may cause serious health effects and significant 
adverse environmental effects. Based on this information, the PMN 
substance meets the concern criteria at Sec.  721.170(b)(3)(i), 
(b)(3)(ii), and (b)(4)(iii).
    Recommended testing: EPA has determined that the results of a 90-
day inhalation toxicity test (OPPTS Test Guideline 870.3465); a 2 
generation reproduction and fertility effects test (OPPTS Test 
Guideline 870.3200); a porous pot test (OPPTS Test Guideline 835.3220); 
and a daphnid chronic toxicity test (OPPTS Test Guideline 850.1300) 
would help characterize the human health and environmental effects of 
the PMN substance.
    CFR citation: 40 CFR 721.10470.

PMN Number P-03-622

    Chemical name: 2-Propenoic acid, 1,1'-(3-methyl-1,5-pentanediyl) 
ester.
    CAS number: 64194-22-5.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as a component of a UV 
coating agent. Based on SAR analysis of test data on analogous 
acrylates, EPA identified concerns for carcinogenicity and 
sensitization. In addition, based on EcoSAR analysis of test data on 
analogous acrylates, EPA predicts toxicity to aquatic organisms may 
occur if releases of the PMN substance to surface waters, from uses 
other than as described in the PMN, exceed releases from the use 
described in the PMN. As described in the PMN, the substance will be 
imported and not manufactured in the United States. For the use 
described in the PMN, significant worker exposures are not expected 
during processing and use activities for the uses described in the PMN, 
and significant environmental releases are not expected. Therefore, EPA 
has not determined that the proposed processing or use of the substance 
may present an unreasonable risk. EPA has determined, however, that 
domestic manufacture or use of the substance other than as described in 
the PMN may cause serious health effects and significant adverse 
environmental effects. Based on this information the PMN substance 
meets the concern criteria at Sec.  721.170(b)(1)(i)(C), (b)(3)(ii), 
and (b)(4)(ii).
    Recommended testing: EPA has determined that the results of a 
carcinogenicity test (OPPTS Test Guideline 870.4200); a fish acute 
toxicity test, freshwater and marine (OPPTS Test Guideline 850.1075); 
an aquatic invertebrate acute toxicity test, freshwater daphnids (OPPTS 
Test Guideline 850.1010); and an algal toxicity test (OCSPP Test 
Guideline 850.4500) would help to characterize the human health and 
environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10471.

PMN Number P-03-645

    Chemical name: 1,3-Benzenedimethanamine, polymers with 
epichlorohydrin-polyethylene glycol reaction products.
    CAS number: 652968-34-8.
    Basis for action: The PMN states that the substance will be used as 
a water retention aid for ornamental plants. Based on analogous 
swellable, high molecular weight polymers, EPA identified concerns for 
lung toxicity and cancer. As described in the PMN, the substance will 
be imported and not manufactured in the United States. For the use 
described in the PMN, significant worker exposures are not expected 
during processing and use activities for the uses described in the PMN. 
Therefore, EPA has not determined that the proposed processing or use 
of the substance may present an unreasonable risk. EPA has determined, 
however, that any domestic manufacture of the PMN substance may cause 
serious health effects. Based on this information, the PMN substance 
meets the concern criteria at Sec.  721.170(b)(1)(i)(C) and (b)(3)(ii).
    Recommended testing: EPA has determined that the results of a 90-
day inhalation toxicity test (OPPTS Test Guideline 870.3465) with a 60-
day holding period, and a teabag test for water retention capacity (see 
http://www.epa.gov/oppt/newchems/pubs/teabag.pdf) would help 
characterize the human health effects of the PMN substance.
    CFR citation: 40 CFR 721.10472.

PMN Number P-03-865

    Chemical name: 1-Propanaminium, 3-amino-N-(2-carboxyethyl)-N,N-
dimethyl-, N-coco acyl derivs., inner salts.
    CAS number: 499781-63-4.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as a non-corrosive foamer in 
the oil and gas industry. Based on test data on the PMN substance, and 
EcoSAR analysis of test data on analogous amphoteric and cationic 
surfactants, EPA predicts toxicity to aquatic organisms may occur at 
concentrations that exceed 85 ppb of the PMN substance in surface 
waters. As described in the PMN, EPA does not expect releases of the 
substance to surface waters in concentrations that exceed 85 ppb. 
Therefore, EPA has not determined that the proposed manufacturing, 
processing, or use of the substance may present an unreasonable risk. 
EPA has determined, however, that any use of the substance resulting in 
surface water concentrations exceeding 85 ppb may cause significant 
adverse environmental effects. Based on this information, the PMN 
substance meets the concern criteria at Sec.  721.170(b)(4)(i) and 
(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a fish

[[Page 58678]]

acute toxicity test, freshwater and marine (OPPTS Test Guideline 
850.1075) would help characterize the environmental effects of the PMN 
substance.
    CFR citation: 40 CFR 721.10473.

PMN Number P-04-107

    Chemical name: Substituted amino ethane sulfonic acid salt 
(generic).
    CAS number: Not available.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be a contained use in digital 
and imaging products. Based on EcoSAR analysis of test data on 
analogous anionic surfactants, EPA predicts toxicity to aquatic 
organisms may occur at concentrations that exceed 4 ppb of the 
substance in surface waters for greater than 20 days per year. This 20-
day criterion is derived from partial life cycle tests (daphnid chronic 
and fish early life stage tests) that typically range from 21 to 28 
days in duration. EPA predicts toxicity to aquatic organisms may occur 
if releases of the PMN substance to surface water, from uses other than 
as described in the PMN, exceed releases from the use described in the 
PMN. For the use described in the PMN, environmental releases did not 
exceed 4 ppb more than 20 days per year. Therefore, EPA has not 
determined that the proposed manufacturing, processing, or use of the 
substance may present an unreasonable risk. EPA has determined, 
however, that any use of the substance other than as described in the 
PMN may cause significant adverse environmental effects. Based on this 
information, the PMN substance meets the concern criteria at Sec.  
721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a fish 
acute toxicity test, freshwater and marine (OPPTS Test Guideline 
850.1075); an aquatic invertebrate acute toxicity test, freshwater 
daphnids (OPPTS Test Guideline 850.1010); and an algal toxicity test 
(OCSPP Test Guideline 850.4500) would help characterize the 
environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10474.

PMN Number P-04-118

    Chemical name: Hexanedioic acid, compd. with N1-(6-aminohexyl)-N1-
methyl-1,6-hexanediamine (1:1).
    CAS number: 659733-29-6.
    Basis for action: The PMN states that the substance will be used as 
an intermediate for polymer manufacture. Based on SAR analysis of test 
data on analogous hexamethyl diamine, EPA identified concerns for 
immunotoxicity, systemic toxicity, developmental toxicity, and 
reproductive toxicity. In addition, based on EcoSAR analysis of test 
data on analogous aliphatic amines, EPA predicts toxicity to aquatic 
organisms may occur at concentrations that exceed 20 ppb of the PMN 
substance in surface waters. As described in the PMN, EPA does not 
expect significant worker exposures or releases of the substance to 
surface waters in concentrations that exceed 20 ppb. Therefore, EPA has 
not determined that the proposed manufacturing, processing, or use of 
the substance may present an unreasonable risk. EPA has determined, 
however, that any use of the substance other than as intermediate for 
polymer manufacture, or any use of the substance resulting in surface 
water concentrations exceeding 20 ppb may cause serious health effects 
and significant adverse environmental effects. Based on this 
information, the PMN substance meets the concern criteria at Sec.  
721.170(b)(3)(ii) and (b)(4)(ii).
    Recommended testing: EPA has determined that the results of a 
prenatal developmental toxicity test (OPPTS Test Guideline 870.3700); a 
reproduction and fertility effects test (OPPTS Test Guideline 
870.3800); an immunotoxicity test (OPPTS Test Guideline 870.7800); a 
fish early life-stage toxicity test (OPPTS Test Guideline 850.1400); 
and a daphnid chronic toxicity test (OPPTS Test Guideline 850.1300) 
would help characterize the human health and environmental effects of 
the PMN substance.
    CFR citation: 40 CFR 721.10475.

PMN Number P-04-275

    Chemical name: Oxetane, 3-(bromomethyl)-3-methyl-.
    CAS number: 78385-26-9.
    Basis for action: The PMN substance will be used as a chemical 
intermediate. Based on SAR analysis of test data on analogous chemical 
substances EPA identified concerns for cancer for the PMN material from 
dermal exposures. For the use described in the PMN, significant worker 
exposures are unlikely due to the use of impervious clothing. 
Therefore, EPA has not determined that manufacturing, processing, and 
use of the substance may present an unreasonable risk. EPA has 
determined, however, any use of the substance without impervious 
clothing where there is a potential for dermal exposures, or any use of 
the substance other than as an intermediate for the pharmaceutical, 
photographic, and other fine chemical industries may cause serious 
health effects. Based on this information the PMN substance meets the 
concern criteria at Sec.  721.170(b)(1)(i)(C).
    Recommended testing: EPA has determined that an in vivo 
micronucleus assay in erythrocytes (OPPTS Test Guideline 870.5395 or 
OECD Test Guideline 474), with exposure by the intraperitoneal route, 
would help to characterize the human health effects of the PMN 
substance.
    CFR citation: 40 CFR 721.10476.

PMN Number P-04-290

    Chemical name: Acrylate ester (generic).
    CAS number: Not available.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as a monomer in radiation 
cured inks and coatings. Based on EcoSAR analysis of test data on 
analogous acrylates, EPA predicts toxicity to aquatic organisms may 
occur at concentrations that exceed 1 ppb of the substance in surface 
waters for greater than 20 days per year. This 20-day criterion is 
derived from partial life cycle tests (daphnid chronic and fish early 
life stage tests) that typically range from 21 to 28 days in duration. 
EPA predicts toxicity to aquatic organisms may occur if releases of the 
PMN substance to surface water, from uses other than as described in 
the PMN, exceed releases from the use described in the PMN. For the use 
described in the PMN, environmental releases did not exceed 1 ppb more 
than 20 days per year. Therefore, EPA had not determined that the 
proposed manufacturing, processing, or use of the substance may present 
an unreasonable risk. EPA has determined, however, that use of the 
substance other than as described in the PMN may cause significant 
adverse environmental effects. Based on this information, the PMN 
substance meets the concern criteria at Sec.  721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a fish 
acute toxicity test, freshwater and marine (OPPTS Test Guideline 
850.1075); an aquatic invertebrate acute toxicity test, freshwater 
daphnids (OPPTS Test Guideline 850.1010); and an algal toxicity test 
(OCSPP Test Guideline 850.4500) would help characterize the 
environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10477.

PMN Number P-04-318

    Chemical name: Polyether polyol (generic).
    CAS number: Not available.
    Basis for action: The PMN states that the substance will be used as 
an intermediate for urethane polymers.

[[Page 58679]]

Based on SAR analysis of test data on similar molecular structure 
chemicals, EPA identified concerns for developmental kidney and liver 
toxicity. In addition, based on EcoSAR analysis of test data on 
analogous nonionic surfactants, EPA predicts toxicity to aquatic 
organisms may occur at concentrations that exceed 30 ppb of the 
substance in surface waters. For the use described in the PMN, 
significant worker exposures are not expected and the substance is not 
released to surface waters. Therefore, EPA has not determined that the 
proposed manufacturing, processing, or use of the substance may present 
an unreasonable risk. EPA has determined, however, that any use of the 
substance other than as an intermediate for urethane polymers, or any 
use of the substance resulting in surface water concentrations 
exceeding 30 ppb may cause serious health effects and significant 
environmental effects. Based on this information, the PMN substance 
meets the concern criteria at Sec.  721.170(b)(3)(ii) and (b)(4)(ii).
    Recommended testing: EPA has determined that the results of an 
acute oral toxicity test (OPPTS Test Guideline 870.1100 or OECD Test 
Guideline 425); a bacterial reverse mutation test (OPPTS Test Guideline 
870.5100); a mammalian erythrocyte micronucleus test (intraperitoneal 
route) (OPPTS Test Guideline 870.5395); a repeated dose 28-day oral 
toxicity in rodents (OPPTS Test Guideline 870.3050 or OECD Test 
Guideline 407), which should include, for all test doses, a 
neurotoxicity functional observational battery, as described in 
neurotoxicity screening battery test (OPPTS Test Guideline 870.6200); a 
prenatal developmental toxicity test (one species, oral route) (OPPTS 
Test Guideline 870.3700); a Zahn-Wellens/EMPA test (OPPTS Test 
Guideline 835.3200); an aerobic aquatic biodegredation test (OPPTS Test 
Guideline 835.3100); a fish acute toxicity test, freshwater and marine 
(OPPTS Test Guideline 850.1075); an aquatic invertebrate acute toxicity 
test, freshwater daphnids (OPPTS Test Guideline 850.1010); and an algal 
toxicity test (OCSPP Test Guideline 850.4500) would help characterize 
the human health, environmental and fate effects for PMN substance.
    CFR citation: 40 CFR 721.10478.

PMN Number P-04-335

    Chemical name: Quaternary ammonium compounds, tris(hydrogenated 
tallow alkyl)methyl, chlorides.
    CAS number: 308074-73-9.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as a rheology additive. 
Based on EcoSAR analysis of test data on analogous dialkyl cationic 
surfactants, EPA predicts toxicity to aquatic organisms may occur at 
concentrations that exceed 1 ppb of the substance in surface waters for 
greater than 20 days per year. This 20-day criterion is derived from 
partial life cycle tests (daphnid chronic and fish early life stage 
tests) that typically range from 21 to 28 days in duration. EPA 
predicts toxicity to aquatic organisms may occur if releases of the PMN 
substance to surface water, from uses other than as described in the 
PMN, exceed releases from the use described in the PMN. For the use 
described in the PMN, environmental releases did not exceed 1 ppb more 
than 20 days per year. Therefore, EPA has not determined that the 
proposed manufacturing, processing, or use of the substance may present 
an unreasonable risk. EPA has determined, however, that use of the 
substance other than as described in the PMN may cause significant 
adverse environmental effects. Based on this information, the PMN 
substance meets the concern criteria at Sec.  721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a fish 
acute toxicity test, freshwater and marine (OPPTS Test Guideline 
850.1075); an aquatic invertebrate acute toxicity test, freshwater 
daphnids (OPPTS Test Guideline 850.1010); and an algal toxicity test 
(OCSPP Test Guideline 850.4500) would help characterize the 
environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10479.

PMN Number P-04-384

    Chemical name: Trimethylolpropane polyol, aminated (generic).
    CAS number: Not available.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as a resin curing agent. 
Based on EcoSAR analysis of test data on analogous aliphatic amines, 
EPA predicts toxicity to aquatic organisms may occur at concentrations 
that exceed 9 ppb of the PMN substance in surface waters. As described 
in the PMN, the substance is not released to surface waters. Therefore, 
EPA has not determined that the proposed manufacturing and processing 
of the substance may present an unreasonable risk. EPA has determined, 
however, that any use of the substance resulting in surface water 
concentrations exceeding 9 ppb may cause significant adverse 
environmental effects. Based on this information, the PMN substance 
meets the concern criteria at Sec.  721.170(b)(4)(ii).
    Recommended testing: EPA has determined that results of a ready 
biodegradability test (OPPTS Test Guideline 835.3110); a fish acute 
toxicity test, freshwater and marine (OPPTS Test Guideline 850.1075); a 
fish acute toxicity test mitigated by humic acid (OPPTS Test Guideline 
850.1085); an aquatic invertebrate acute toxicity test, freshwater 
daphnids (OPPTS Test Guideline 850.1010); and an algal toxicity test 
(OCSPP Test Guideline 850.4500) would help characterize the 
environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10480.

PMN Numbers P-04-429, P-04-430, P-04-431, and P-04-432

    Chemical names: (P-04-429) Siloxanes and Silicones, Me vinyl, 
hydroxy-terminated, reaction products with silica; (P-04-430) Siloxanes 
and Silicones, di-Me, Me vinyl, hydroxy-terminated, reaction products 
with silica; (P-04-431) Siloxanes and Silicones, di-Me, Me vinyl, 
hydroxy-terminated, reaction products with [(ethenyldimethylsilyl)oxy]-
modified silica; and (P-04-432) Siloxanes and Silicones, Me vinyl, 
hydroxy-terminated, reaction products with [(ethenyldimethylsilyl)oxy]-
modified silica.
    CAS numbers: (P-04-429) 630106-01-3; (P-04-430) 630106-00-2; (P-01-
431) 630106-04-6; and (P-04-432) 630106-02-4.
    Basis for action: The consolidated PMN states that the substances 
will be used as chemical fillers. Based on high molecular weight 
polymers, EPA identified concerns for lung overload. Further, based on 
analogy to respirable, poorly soluble particulates, under the 
subcategory of crystalline silica, EPA identified concerns for lung 
toxicity and cancer. For the use described in the PMN, significant 
worker inhalation exposures are not expected as the substance is used 
in a liquid form. Therefore, EPA has not determined that the proposed 
manufacturing, processing, and use of the substances may present an 
unreasonable risk. EPA has determined, however, that any use of the 
substances in a powder form may cause serious health effects. Based on 
this information, the PMN substances meet the concern criteria at Sec.  
721.170(b)(1)(i)(C) and (b)(3)(ii).
    Recommended testing: EPA has determined that a 90-day inhalation 
toxicity test (OPPTS Test Guideline 870.3465) in rats with special 
attention to histopathology (inflammation and cell proliferation) of 
the lung tissues and

[[Page 58680]]

to various parameters of the bronchoalveolar lavage fluid (BALF) with a 
recovery period of 60 days; and a carcinogenicity test (OPPTS Test 
Guideline 870.4200) in rats would help characterize the human health 
effects of the PMN substance.
    CFR citations: 40 CFR 721.10481 (P-04-429); 40 CFR 721.10482 (P-04-
430); 40 CFR 721.10483 (P-01-431); and 40 CFR 721.10484 (P-04-432).

PMN Number P-04-479

    Chemical name: Reaction products of alcohols, alkyl alcohols, amino 
alcohols and methanol sodium salts (generic).
    CAS number: Not available.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as a cleaning agent. Based 
on EcoSAR analysis of test data on analogous aliphatic amines, EPA 
predicts toxicity to aquatic organisms may occur at concentrations that 
exceed 30 ppb of the substance in surface waters for greater than 20 
days per year. This 20-day criterion is derived from partial life cycle 
tests (daphnid chronic and fish early life stage tests) that typically 
range from 21 to 28 days in duration. EPA predicts toxicity to aquatic 
organisms may occur if releases of the PMN substance to surface water, 
from uses other than as described in the PMN, exceed releases from the 
use described in the PMN. For the use described in the PMN, 
environmental releases did not exceed 30 ppb more than 20 days per 
year. Therefore, EPA has not determined that the proposed 
manufacturing, processing, or use of the substance may present an 
unreasonable risk. EPA has determined, however, that use of the 
substance other than as described in the PMN may cause significant 
adverse environmental effects. Based on this information, the PMN 
substance meets the concern criteria at Sec.  721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a fish 
early-life stage toxicity test (OPPTS Test Guideline 850.1400) and a 
daphnid chronic toxicity test (OPPTS Test Guideline 850.1300) would 
help characterize the environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10485.

PMN Number P-04-591

    Chemical name: Alkyl substituted amino-benzamide (generic).
    CAS number: Not available.
    Basis for action: The PMN states that the substance will be used as 
an acetaldehyde scavenger for plastic bottle production. Based on 
EcoSAR analysis of test data on analogous anilines, EPA predicts 
toxicity to aquatic organisms may occur if releases of the PMN 
substance to surface waters, from uses other than as described in the 
PMN, exceed releases from the use described in the PMN. For the use 
described in the PMN, significant environmental releases are not 
expected. Therefore, EPA has not determined that the proposed 
manufacturing, processing, or use of the substance may present an 
unreasonable risk. EPA has determined, however, that use of the 
substance other than as an acetaldehyde scavenger for plastic bottle 
production could result in exposures which may cause significant 
adverse environmental effects. Based on this information, the PMN 
substance meets the concern criteria as Sec.  721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a ready 
biodegradability test (OPPTS Test Guideline 835.3110); a fish acute 
toxicity test, freshwater and marine (OPPTS Test Guideline 850.1075); 
an aquatic invertebrate acute toxicity test, freshwater daphnids (OPPTS 
Test Guideline 850.1010); and an algal toxicity test (OCSPP Test 
Guideline 850.4500) would help characterize the environmental effects 
of the PMN substance.
    CFR citation: 40 CFR 721.10486.

PMN Numbers P-04-599, P-04-600, P-04-605, and P-04-606

    Chemical name: Alkylbenzenes sulfonic acids, metal salts (generic).
    CAS number: Not available.
    Basis for action: The PMNs state that the generic (non-
confidential) use of the substances will be as metalworking detergents. 
Based on EcoSAR analysis of test data on analogous anionic surfactants, 
EPA predicts toxicity to aquatic organisms may occur at concentrations 
that exceed 60 ppb of the substances in surface waters for greater than 
20 days per year. This 20-day criterion is derived from partial life 
cycle tests (daphnid chronic and fish early life stage tests) that 
typically range from 21 to 28 days in duration. EPA predicts toxicity 
to aquatic organisms may occur if releases of the PMN substances to 
surface water, from uses other than as described in the PMNs, exceed 
releases from the use described in the PMNs. For the use described in 
the PMNs, environmental releases did not exceed 60 ppb more than 20 
days per year. Therefore, EPA has not determined that the proposed 
manufacturing, processing, or use of the substances may present an 
unreasonable risk. EPA has determined, however, that use of the 
substances other than as described in the PMNs may cause significant 
adverse environmental effects. Based on this information, the PMN 
substances meet the concern criteria as Sec.  721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a ready 
biodegradability test (OPPTS Test Guideline 835.3110); a fish acute 
toxicity test, freshwater and marine (OPPTS Test Guideline 850.1075); 
an aquatic invertebrate acute toxicity test, freshwater daphnids (OPPTS 
Test Guideline 850.1010); and an algal toxicity test (OCSPP Test 
Guideline 850.4500) would help characterize the environmental effects 
of the PMN substances.
    CFR citation: 40 CFR 721.10487.

PMN Number P-04-636

    Chemical name: Cuprate, [[[[[[[(sulfonaphthalenyl)]azo]-
(substitutedphenyl)]azo]-(substitutedsulfonaphthalenyl)]azo]-
substituted phenyl-substituted heteromonocycle], sodium salts 
(generic).
    CAS number: Not available.
    Basis for action: The PMN states that the substance will be used as 
an ink jet dye. Based on SAR analysis of test data on structurally 
similar substances, EPA identified concerns for oncogenicity. As 
described in the PMN, inhalation exposures are not expected for the use 
specified due to the use of a NIOSH-certified respirator with an APF of 
at least 5. Therefore, EPA has not determined that the proposed 
manufacturing, processing, or use of the substance may present an 
unreasonable risk. EPA has determined, however, that uses of the 
substance without respiratory protection where there is a potential for 
inhalation exposure may cause serious health effects. Based on this 
information, the PMN substance meets the concern criteria at Sec.  
721.170(b)(1)(i)(C) and (b)(3)(ii).
    Recommended testing: EPA has determined that the results of an 
unscheduled deoxyribonucleic acid (DNA) synthesis in mammalian cells in 
culture (OPPTS Test Guideline 870.5550), and if warranted by the 
results of the first test, a carcinogenicity test (OPPTS Test Guideline 
870.4200) would help characterize the human health effects of the PMN 
substance.
    CFR citation: 40 CFR 721.10488.

PMN Number P-04-718

    Chemical name: Substituted aryl sulfonium polyfluorophosphate salts 
(generic).
    CAS number: Not available.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as a catalyst. Based on SAR 
analysis of test data on structurally

[[Page 58681]]

similar substances, EPA identified concerns for corrosion and ocular 
lethality. In addition, based on EcoSAR analysis of test data on 
analogous cationic surfactants, EPA predicts toxicity to aquatic 
organisms may occur at concentrations that exceed 6 ppb of the PMN 
substance in surface waters. As described in the PMN, significant 
worker exposures are not expected as the PMN is used in the form of a 
liquid and releases of the substance to surface waters are not 
expected. Therefore, EPA has not determined that the proposed 
manufacturing, processing, or use may present an unreasonable risk. EPA 
has determined, however, that any use of the substance in the form of a 
powder or solid, or any use of the substance resulting in surface water 
concentrations exceeding 6 ppb may cause serious health effects and 
significant adverse environmental effects. Based on this information, 
the PMN substance meets the concern criteria at Sec.  721.170(b)(3)(ii) 
and (b)(4)(ii).
    Recommended testing: EPA has determined that the results of an 
acute eye irritation test (OPPTS Test Guideline 870.2400); a fish acute 
toxicity test, freshwater and marine (OPPTS Test Guideline 850.1075); 
an aquatic invertebrate acute toxicity test, freshwater daphnids (OPPTS 
Test Guideline 850.1010); and an algal toxicity test (OCSPP Test 
Guideline 850.4500) would help characterize the human health and 
environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10489.

PMN Number P-04-834

    Chemical name: HDI biuret, hydroxyethyl methacrylate prepolymer 
(generic).
    CAS number: Not available.
    Effective date of TSCA section 5(e) consent order: March 20, 2006.
    Basis for TSCA section 5(e) consent order: The PMN states that the 
substance will be used as an ingredient in 2-component polyurethane 
coatings. Based on test data on analogous diisocyanates, EPA identified 
concerns for dermal and respiratory sensitization, pulmonary toxicity, 
and carcinogenicity from dermal and inhalation exposures. The consent 
order was issued under TSCA sections 5(e)(1)(A)(i), 5(e)(1)(A)(ii)(I), 
and 5(e)(1)(A)(ii)(II) based on a finding that this substance may 
present an unreasonable risk of injury to human health, the substance 
may be produced in substantial quantities, and there may be significant 
(or substantial) human exposure to the substance. To protect against 
this exposure and risk, the consent order requires:
    1. Use of personal protective equipment including impervious gloves 
(when there is potential dermal exposure) and either a NIOSH-certified 
respirator with an APF of at least 25, or compliance with a NCEL of 
0.05 mg/m\3\ as an 8-hour time-weighted average (when there is 
potential inhalation exposure).
    2. Establishment and use of a hazard communication program.
    3. Submission of certain human health testing prior to exceeding 
two confidential production volume limits specified in the consent 
order.
    The SNUR designates as a ``significant new use'' the absence of 
these protective measures.
    Recommended testing: EPA has determined that the results of a 
dermal sensitization test (OPPTS Test Guideline 870.2600) and a 90-day 
inhalation toxicity test (OPPTS Test Guideline 870.3465) would help 
characterize the human health effects of the PMN substance. The PMN 
submitter has agreed not to exceed the first confidential production 
volume limit specified in the consent order without performing the 
dermal sensitization test, and has agreed not to exceed the second 
confidential production volume limit without performing the 90-day 
toxicity test. The order's restrictions on manufacture, import, 
processing, distribution in commerce, use, and disposal of the PMN will 
remain in effect until the consent order is modified or revoked by EPA 
based on submission of that or other relevant information.
    CFR citation: 40 CFR 721.10490.

PMN Number P-05-55

    Chemical name: Benzenepropanal,.alpha.-methyl-.
    CAS number: 5445-77-2.
    Basis for action: The PMN states that the substance will be used as 
a site-limited intermediate. Based on SAR analysis of test data on 
structurally similar substances, EPA has identified concerns for 
developmental toxicity. For the use described in the PMN, significant 
dermal and inhalation exposures are not expected. Therefore, EPA has 
not determined that proposed manufacturing, processing, or use of the 
substance may present an unreasonable risk. EPA has determined, 
however, that use of the PMN substance other than as a site-limited 
intermediate may cause serious health effects. Based on this 
information the PMN substance meets the concern criteria at Sec.  
721.170(b)(3)(ii).
    Recommended testing: EPA has determined that the results of a 
prenatal developmental toxicity test (OPPTS Test Guideline 870.3700), 
by the dermal route in mice, would help characterize the human health 
effects of the PMN substance.
    CFR citation: 40 CFR 721.10491.

PMN Number P-05-301

    Chemical name: Trisphenol (generic).
    CAS number: Not available.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as a hardener for epoxy 
resin. Based on EcoSAR analysis of test data on analogous phenols, EPA 
predicts toxicity to aquatic organisms may occur at concentrations that 
exceed 20 ppb of the PMN substance in surface waters. As described in 
the PMN, releases of the PMN substance are not expected to result in 
surface water concentrations that exceed 20 ppb. Therefore, EPA has not 
determined that manufacturing, processing, and use of the substance may 
present an unreasonable risk. EPA has determined, however, that any use 
of the substance resulting in surface water concentrations exceeding 20 
ppb may cause significant adverse environmental effects. Based on this 
information the PMN substance meets the concern criteria at Sec.  
721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a fish 
acute toxicity test, freshwater and marine (OPPTS Test Guideline 
850.1075); an aquatic invertebrate acute toxicity test, freshwater 
daphnids (OPPTS Test Guideline 850.1010); and an algal toxicity test 
(OCSPP Test Guideline 850.4500) would help to characterize the 
environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10492.

PMN Number P-05-417

    Chemical name: Tris-alkyl-alkoxy melamine polymer (generic).
    CAS number: Not available.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as a crosslinking resin. 
Based on test data on the PMN substance, EPA predicts toxicity to 
aquatic organisms may occur at concentrations that exceed 5 ppb of the 
PMN substance in surface waters. As described in the PMN, releases of 
the PMN substance are not expected to result in surface water 
concentrations that exceed 5 ppb. Therefore, EPA has not determined 
that the proposed manufacturing, processing, or use of the substance 
may present an unreasonable risk. EPA has determined, however, that any 
use of the substance resulting in

[[Page 58682]]

surface water concentrations exceeding 5 ppb may cause significant 
adverse environmental effects. Based on this information the PMN 
substance meets the concern criteria at Sec.  721.170(b)(4)(i).
    Recommended testing: EPA has determined that the results of a fish 
early-life stage toxicity test (OPPTS Test Guideline 850.1400); a 
daphnid chronic toxicity test (OPPTS Test Guideline 850.1300), and an 
algal toxicity test (OCSPP Test Guideline 850.4500) on the hydrolysis 
products of the PMN substance would help to characterize the 
environmental effects of the PMN substance and its hydrolysis products.
    CFR citation: 40 CFR 721.10493.

PMN Number P-05-501

    Chemical name: Reaction product of trimethylolpropane triacrylate 
and alkylene imine (generic).
    CAS number: Not available.
    Basis for action: The PMN substance will be used as an amine 
synergist for coatings and inks. Based on EcoSAR analysis of test data 
on analogous aliphatic amines, EPA predicts toxicity to aquatic 
organisms may occur at concentrations that exceed 5 ppb in surface 
waters. As described in the PMN, the substance is not released to 
surface waters. Therefore, EPA has not determined that the proposed 
manufacturing, processing, or use of the substance may present an 
unreasonable risk. EPA has determined, however, that any use of the 
substance resulting in surface water concentrations exceeding 5 ppb may 
cause significant adverse environmental effects. Based on this 
information the PMN substance meets the concern criteria at Sec.  
721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a fish 
acute toxicity test, freshwater and marine (OPPTS Test Guideline 
850.1075); a fish acute toxicity test mitigated by humic acid (OPPTS 
Test Guideline 850.1085); an aquatic invertebrate acute toxicity test, 
freshwater daphnids (OPPTS Test Guideline 850.1010); and an algal 
toxicity test (OCSPP Test Guideline 850.4500) would help to 
characterize the environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10494.

PMN Number P-05-634

    Chemical name: Metal silicate (generic).
    CAS number: Not available.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as an additive use 
restricted to enclosed toner cartridges. Based on SAR analysis of test 
data on analogous respirable, poorly soluble particulates, EPA 
identified concerns for lung effects for the PMN substance. Based on 
physical properties, EPA identified concerns for potential systemic 
effects from dermal exposure to the PMN substance. As described in the 
PMN, the substance will be imported and not manufactured in the United 
States. For the use described in the PMN, worker dermal and inhalation 
exposures are not expected during processing and use activities. 
Therefore, EPA has not determined that the proposed processing or use 
of the substance may present an unreasonable risk. EPA has determined, 
however, that domestic manufacture, or use of the substance other than 
as described in the PMN may cause serious health effects. Based on this 
information, the PMN substance meets the concern criteria at Sec.  
721.170(b)(3)(ii).
    Recommended testing: EPA has determined that a 90-day inhalation 
toxicity test (OPPTS Test Guideline 870.3465) in rats with special 
attention to histopathology (inflammation and cell proliferation) of 
the lung tissues and to various parameters of the BALF with a recovery 
period of 60 days would help characterize the human health effects of 
the PMN substance.
    CFR citation: 40 CFR 721.10495.

PMN Number P-06-9

    Chemical name: Amino alkoxy polydimethylsiloxane, hydroxy-
terminated (generic).
    CAS number: Not available.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as a textile additive. Based 
on EcoSAR analysis of test data on analogous polycationic polymers, EPA 
predicts toxicity to aquatic organisms may occur at concentrations that 
exceed 10 ppb of the PMN substance in surface waters. As described in 
the PMN, the substance is not released to surface waters. Therefore, 
EPA has not determined that the proposed manufacturing, processing, or 
use of the substance may present an unreasonable risk. EPA has 
determined, however, that any use of the substance resulting in surface 
water concentrations exceeding 10 ppb may cause significant adverse 
environmental effects. Based on this information, the PMN substance 
meets the concern criteria at Sec.  721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a fish 
acute toxicity test, freshwater and marine (OPPTS Test Guideline 
850.1075); an aquatic invertebrate acute toxicity test, freshwater 
daphnids (OPPTS Test Guideline 850.1010); and an algal toxicity test 
(OCSPP Test Guideline 850.4500) would help characterize the 
environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10496.

PMN Numbers P-06-276, P-06-277, P-06-278, P-06-279, P-06-280, and P-06-
281

    Chemical names: (P-06-276 and P-06-279) Substituted alkyl ester, 
hydrolysis products with silica and substituted silane (generic); (P-
06-277 and P-06-280) Substituted alkyl ester, hydrolysis products with 
silica (generic); and (P-06-278 and P-06-281) Substituted silane, 
hydrolysis products with silica (generic).
    CAS numbers: Not available.
    Basis for action: The consolidated PMN states that the generic 
(non-confidential) use of the substances will be as components of 
clearcoat. Based on SAR analysis of test data on analogous respirable, 
poorly soluble particulates, EPA identified potential lung and systemic 
effects from inhalation and dermal exposures to the PMN substances. For 
the use described in the consolidated PMN, EPA does not expect 
significant worker exposures to the substances due to the use of 
appropriate impervious gloves and clothing; use of an appropriate 
NIOSH-certified respirator with an APF of at least 5; and no 
manufacturing, processing, or use in the form of a powder. Therefore, 
EPA has not determined that the proposed manufacturing, processing, or 
use of the substances may present an unreasonable risk. EPA has 
determined, however, that any use of the substances without impervious 
gloves and clothing where there is a potential for dermal exposures; 
any use of the substances without a NIOSH-certified respirator with an 
APF of at least 5 where there is a potential for inhalation exposures; 
use of the substances other than as described in the PMN; or 
manufacturing, processing, or use of the substances in the form of a 
powder may cause serious adverse health effects. Based on this 
information, the PMN substances meet the concern criteria at Sec.  
721.170(b)(3)(ii).
    Recommended testing: EPA has determined that the results of a 90-
day inhalation toxicity test (OPPTS Test Guideline 870.3465) would help 
characterize the human health effects of the PMN substances.
    CFR citations: 40 CFR 721.10497 (P-06-276 and P-06-279); 40 CFR 
721.10498 (P-06-277 and P-06-280); and 40 CFR 721.10499 (P-06-278 and 
P-06-281).

[[Page 58683]]

PMN Number P-06-341

    Chemical name: Acrylated mixed metal oxides (generic).
    CAS number: Not available.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as a film coating additive. 
Based on SAR analysis of test data on analogous respirable, poorly 
soluble particulates, EPA identified concerns for potential lung 
effects from inhalation exposures and potential systemic effects from 
dermal exposures. For the use described in the PMN, inhalation and 
dermal exposures are not expected due to use of the substance as a 
liquid and with impervious dermal protection for exposed workers. 
Therefore, EPA has not determined that the proposed manufacturing, 
processing, or use of the substance may present an unreasonable risk. 
EPA has determined, however, that use of the substance without the use 
of impervious dermal protection where there is potential for dermal 
exposures; any manufacture, processing, or use of the substance in the 
form of a powder; or any use of the substance other than as described 
in the PMN may cause serious health effects. Based on this information, 
the PMN substance meets the concern criteria at Sec.  
721.170(b)(3)(ii).
    Recommended testing: EPA has determined that the results of a 90-
day inhalation toxicity test (OPPTS Test Guideline 870.3465) would help 
characterize the human health effects of the PMN substance.
    CFR citation: 40 CFR 721.10500.

PMN Number P-06-542

    Chemical name: Tridecyl phthalate (generic).
    CAS number: Not available.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as a plasticizer. Based on 
SAR analysis of test data on analogous phthalates, EPA identified 
concerns for developmental toxicity. For the use stated in the PMN, 
significant worker or consumer exposures are unlikely. Therefore, EPA 
has not determined that the proposed manufacturing, processing, and use 
of the substance may present an unreasonable risk. EPA has determined, 
however, that any other use of the substance other than as described in 
the PMN may cause serious adverse human health effects. Based on this 
information, the PMN substance meets the concern criteria at Sec.  
721.170(b)(3)(ii).
    Recommended testing: EPA has determined that the results of an oral 
reproduction and fertility effects test (OPPTS Test Guideline 870.3800) 
would help characterize the human health effects of the PMN substance.
    CFR citation: 40 CFR 721.10501.

PMN Number P-06-616

    Chemical name: Modified triethylene glycol dithiol (generic).
    CAS number: Not available.
    Basis for action: The PMN states that the substance will be used as 
a reactive diluent/binder in aerospace sealants. Based on EcoSAR 
analysis of test data on analogous thiols, EPA predicts toxicity to 
aquatic organisms may occur at concentrations that exceed 2 ppb of the 
substance in surface waters. As described in the PMN, the substance is 
not expected to be released to surface waters. Therefore, EPA has not 
determined that the proposed manufacturing, processing, or use of the 
substance may present an unreasonable risk. EPA has determined, 
however, that any use of the substance resulting in surface water 
concentrations exceeding 2 ppb may cause significant adverse 
environmental effects. Based on this information, the PMN substance 
meets the concern criteria at Sec.  721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a ready 
biodegradability test (OPPTS Test Guideline 835.3110); a fish acute 
toxicity test, freshwater and marine (OPPTS Test Guideline 850.1075); 
an aquatic invertebrate acute toxicity test, freshwater daphnids (OPPTS 
Test Guideline 850.1010); and an algal toxicity test (OCSPP Test 
Guideline 850.4500) would help characterize the environmental effects 
of the PMN substance.
    CFR citation: 40 CFR 721.10502.

PMN Number P-06-622

    Chemical name: 1,2-Ethanediol, 1-carbamate.
    CAS number: 5395-01-7.
    Basis for action: The PMN states that the substance will be used as 
an intermediate monomer for polymer synthesis. Based on test data on 
the PMN substance, and SAR analysis of test data on analogous urethanes 
and carbamates, EPA identified concerns for liver toxicity, 
developmental toxicity, and oncogenicity. For the use described in the 
PMN, EPA expects no significant dermal exposures due to the use of 
impervious gloves. Therefore, EPA has not determined that the proposed 
manufacturing, processing, or use of the substance may present an 
unreasonable risk. EPA has determined, however, that any use of the 
substance without impervious gloves where there is a potential for 
dermal exposures may cause serious adverse health effects. Based on 
this information, the PMN substance meets the concern criteria at Sec.  
721.170(b)(1)(i)(C),(b)(3)(i), and (b)(3)(ii).
    Recommended testing: EPA has determined that the results of a 
prenatal developmental toxicity test (OPPTS Test Guideline 870.3700) 
and a carcinogenicity test (OPPTS Test Guideline 870.4200) would help 
characterize the human health effects of the PMN substance.
    CFR citation: 40 CFR 721.10503.

PMN Number P-06-682

    Chemical name: Surface modified magnesium hydroxide (generic).
    CAS number: Not available.
    Basis for action: The PMN states the substance will be used as a 
compatibilizer for flame retardant for plastics. Based on SAR analysis 
of test data on analogous respirable, poorly soluble particulates, EPA 
identified concerns for lung toxicity due to lung overload from 
inhalation exposure to the PMN substance. At the production volume of 
100,000 kgs per year and for the specific use as a compatibilizer for 
flame retardant for plastics, significant worker exposures are not 
expected. Therefore, EPA has not determined that the proposed 
manufacturing, processing, or use of the substance may present an 
unreasonable risk. EPA has determined, however, that any use of the 
substance other than as a compatibilizer for flame retardant for 
plastics, or any use of the substance in quantities greater than 
100,000 kgs per year may cause serious health effects. Based on this 
information, the PMN substance meets the concern criteria at Sec.  
721.170(b)(3)(ii).
    Recommended testing: EPA has determined that a 90-day inhalation 
toxicity test with a 60-day holding period (OPPTS Test Guideline 
870.3465) would help characterize the human health effects of the PMN 
substance.
    CFR citation: 40 CFR 721.10504.

PMN Number P-06-694

    Chemical name: Phosphoric acid, mixed mono- and diesters with 2-
ethyl-1-hexanol and polyethylene glycol mono-C12-16-alkyl 
ethers.
    CAS number: 882693-50-7.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as a hydraulic fluid. Based 
on test data on the PMN substance and EcoSAR analysis of test data on 
analogous anionic surfactants, EPA predicts toxicity to aquatic 
organisms may occur as a result of

[[Page 58684]]

releases of the PMN substance to surface waters from manufacture or 
import in quantities greater than 75,000 kgs per year, or from uses 
other than as stated in the PMN. At the annual production volume of 
75,000 kgs per year, and for the use stated in the PMN, no significant 
environmental releases are expected. Therefore, EPA has not determined 
that the proposed manufacturing, processing, or use of the substance 
may present an unreasonable risk. EPA has determined, however, that any 
use of the substance other than as stated in the PMN, or exceeding an 
annual manufacturing and importation volume of 75,000 kgs may cause 
significant adverse environmental effects. Based on this information, 
the PMN substance meets the concern criteria at Sec.  721.170(b)(4)(i) 
and (b)(4)(ii).
    Recommended testing: EPA has determined that the results of a fish 
acute toxicity test, freshwater and marine (OPPTS Test Guideline 
850.1075) and an aquatic invertebrate acute toxicity test, freshwater 
daphnids (OPPTS Test Guideline 850.1010) would help characterize the 
environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10505.

PMN Numbers P-07-11 and P-08-29

    Chemical name: Alkylated phenols (generic).
    CAS number: Not available.
    Basis for action: The PMNs state that the generic (non-
confidential) use of the substance will be as an antioxidant (P-07-11) 
and an intermediate (P-08-29). Based on test data on P-07-11 and SAR 
analysis of test data on analogous molecular structure chemicals, EPA 
identified concerns for liver effects, thyroid effects, and 
neurotoxicity. As described in the PMNs, worker dermal exposure to the 
PMN substances will be minimal due to impervious gloves. Therefore, EPA 
has not determined that the proposed manufacturing, processing, or use 
of the substance may present an unreasonable risk. EPA has determined, 
however, that use of the substance without the use of impervious gloves 
where there is potential for dermal exposure may cause serious adverse 
health effects. Based on this information, the PMN substance meets the 
concern criteria at Sec.  721.170(b)(3)(i) and (b)(3)(ii).
    Recommended testing: EPA has determined that a repeated dose 90-day 
oral toxicity test in rodents (OPPTS Test Guideline 870.3100) and a 
developmental neurotoxicity test (OPPTS Test Guideline 870.6300) would 
help characterize the health effects of the PMN substances.
    CFR citation: 40 CFR 721.10506.

PMN Number P-07-107

    Chemical name: Biphenyl substituted benzopyran (generic).
    CAS number: Not available.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as a polymer additive. Based 
on EcoSAR analysis of test data on analogous neutral organic chemicals, 
EPA predicts toxicity to aquatic organisms may occur at concentrations 
that exceed 2 ppb of the PMN substance in surface waters. As described 
in the PMN, releases of the PMN substance are not expected to result in 
surface water concentrations that exceed 2 ppb. Therefore, EPA has not 
determined that the proposed manufacturing, processing, or use of the 
substance may present an unreasonable risk. EPA has determined, 
however, that any use of the substance resulting in surface water 
concentrations exceeding 2 ppb may cause significant adverse 
environmental effects. Based on this information, the PMN substance 
meets the concern criteria at Sec.  721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a fish 
acute toxicity test, freshwater and marine (OPPTS Test Guideline 
850.1075); an aquatic invertebrate acute toxicity test, freshwater 
daphnids (OPPTS Test Guideline 850.1010); and an algal toxicity test 
(OCSPP Test Guideline 850.4500) would help characterize the 
environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10507.

PMN Number P-07-161

    Chemical name: Alkene substituted Bis phenol (generic).
    CAS number: Not available.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as a hardener for epoxy 
resins. EPA identified human health and environmental concerns because 
the PMN substance may be a persistent, bio-accumulative, and toxic 
(PBT) chemical, based on the physical/chemical properties of the PMN 
substance, as described in the New Chemicals Program's PBT category (64 
FR 60194, November 4, 1999) (FRL-6097-7). EPA estimates that the 
substance will persist in the environment for more than 2 months and 
estimates a bioaccumulation factor of greater than or equal to 5,000. 
Also, based on SAR analysis of test data on analogous safrole, 
methyleugenal and bisphenol A, EPA identified concerns for 
carcinogenicity and mutagenicity, systemic effects, and endocrine 
disruption. Further, based on EcoSAR analysis of test data on analogous 
phenols, EPA predicts toxicity to aquatic organisms may occur at 
concentrations that exceed 1 ppb of the substance in surface waters. As 
described in the PMN, significant worker exposures are not expected due 
to the use of impervious dermal protective equipment, and the substance 
is not released to surface waters. Therefore, EPA has not determined 
that the proposed manufacturing, processing, or use of the substance 
may present an unreasonable risk. EPA has determined, however, that any 
use of the substance without impervious dermal protection where there 
is a potential for dermal exposures, or any purposeful or predictable 
release of the substance to surface waters may cause serious health 
effects and significant adverse environmental risks. Based on this 
information, the PMN substance meets the concern criteria at Sec.  
721.170(b)(1)(i)(C), (b)(3)(ii), (b)(4)(ii), and (b)(4)(iii).
    Recommended testing: EPA has determined that the results of a ready 
biodegradability test (OPPTS Test Guideline 835.3110); a fish 
bioconcentration test (OPPTS Test Guideline 850.1730); an oral combined 
chronic toxicity/carcinogenicity study (OPPTS Test Guideline 870.4300); 
a fish acute toxicity test, freshwater and marine (OPPTS Test Guideline 
850.1075); an aquatic invertebrate acute toxicity test, freshwater 
daphnids (OPPTS Test Guideline 850.1010); and an algal toxicity test 
(OCSPP Test Guideline 850.5400) would help to characterize the human 
health and environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10508.

PMN Number P-07-204

    Chemical name: Pentane, 1,1,1,2,3,3-hexafluoro-4-(1,1,2,3,3,3-
hexafluoropropoxy)-.
    CAS number: 870778-34-0.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as a heat transfer fluid. 
Based on test data on the PMN substance and SAR analysis of test data 
on analogous perfluorinated substances, EPA identified concerns for 
neurotoxicity, liver effects, and cardiac sensitization from exposures 
to the PMN substance. For the use described in the PMN, EPA does not 
expect significant worker exposures due to the use of impervious 
gloves. Therefore, EPA has not determined that the proposed 
manufacturing, processing, or use of the substance may present an 
unreasonable risk. EPA has determined, however, that any use without 
impervious gloves where there is a potential for dermal

[[Page 58685]]

exposures, or any use of the substance other than as described in the 
PMN may cause serious adverse health effects. Based on this 
information, the PMN substance meets the concern criteria at Sec.  
721.170(b)(3)(i) and (b)(3)(ii).
    Recommended testing: EPA has determined that the results of a 28-
day dermal toxicity test (OPPTS Test Guideline 870.3200) in rats; a 90-
day inhalation toxicity test (OPPTS Test Guideline 870.3465), and a 
test using the ``Standard Test Method for Permeation of Liquids and 
Gases through Protective Clothing Materials under Conditions of 
Continuous Contact'' (ASTM International standard F739) as reported in 
the ``Standard Guide for Documenting the Results of Chemical Permeation 
Testing of Materials Used in Protective Clothing'' (ASTM International 
standard F1194) would help characterize the human health effects of the 
PMN substance.
    CFR citation: 40 CFR 721.10509.

PMN Number P-07-319

    Chemical name: Alkylaminoalcohol (generic).
    CAS number: Not available.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be as a raw material for a 
polymer paint additive. Based on EcoSAR analysis of test data on 
analogous aliphatic amines, EPA predicts toxicity to aquatic organisms 
may occur at concentrations that exceed 1 ppb of the PMN substance in 
surface waters. As described in the PMN, the substance is not released 
to surface waters. Therefore, EPA has not determined that the proposed 
manufacturing, processing, or use of the substance may present an 
unreasonable risk. EPA has determined, however, that any use of the 
substance resulting in surface water concentrations exceeding 1 ppb may 
cause significant adverse environmental effects. Based on this 
information, the PMN substance meets the concern criteria at Sec.  
721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a fish 
acute toxicity test, freshwater and marine (OPPTS Test Guideline 
850.1075); an aquatic invertebrate acute toxicity test, freshwater 
daphnids (OPPTS Test Guideline 850.1010); and an algal toxicity test 
(OCSPP Test Guideline 850.4500) would help characterize the 
environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10510.

PMN Numbers P-07-320, P-07-321, P-07-322, P-07-323, and P-07-324

    Chemical name: Quaternary ammonium salts (generic).
    CAS number: Not available.
    Basis for action: The consolidated PMN states that the generic 
(non-confidential) use of the substances will be as inhibitors for oil 
field applications. Based on EcoSAR analysis of test data on analogous 
cationic surfactants, EPA predicts toxicity to aquatic organisms may 
occur at concentrations that exceed 20 ppb of the substance in surface 
waters for greater than 20 days per year. This 20-day criterion is 
derived from partial life cycle tests (daphnid chronic and fish early 
life stage tests) that typically range from 21 to 28 days in duration. 
EPA predicts toxicity to aquatic organisms may occur if releases of the 
PMN substance to surface water, from uses other than as described in 
the PMN, exceed releases from the use described in the PMN. For the use 
described in the PMN, environmental releases did not exceed 20 ppb more 
than 20 days per year. Therefore, EPA has not determined that the 
proposed manufacturing, processing, or use of the substances may 
present an unreasonable risk. EPA has determined, however, that use of 
the substances other than as described in the PMN could result in 
exposures which may cause significant adverse environmental effects. 
Based on this information, the PMN substance meets the concern criteria 
at Sec.  721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a fish 
acute toxicity test, freshwater and marine (OPPTS Test Guideline 
850.1075); a fish acute toxicity test mitigated by humic acid (OPPTS 
Test Guideline 850.1085); an aquatic invertebrate acute toxicity test, 
freshwater daphnids (OPPTS Test Guideline 850.1010); and an algal 
toxicity test (OCSPP Test Guideline 850.4500) would help characterize 
the environmental effects of the PMN substances.
    CFR citations: 40 CFR 721.10511.

PMN Numbers P-07-563 and P-07-564

    Chemical name: Fatty acid maleic acid amides (generic).
    CAS number: Not available.
    Basis for action: The consolidated PMN states that the substances 
will be used as emulsifiers for oil well drilling fluids. Based on 
EcoSAR analysis of test data on analogous aliphatic amines, EPA 
predicts toxicity to aquatic organisms may occur at concentrations that 
exceed 10 ppb of the PMN substances in surface waters. As described in 
the PMN, the substances are not released to surface waters. Therefore, 
EPA has not determined that the proposed manufacturing, processing, or 
use of the substances may present an unreasonable risk. EPA has 
determined, however, that any use of the substances resulting in 
surface water concentrations exceeding 10 ppb may cause significant 
adverse environmental effects. Based on this information, the PMN 
substances meet the concern criteria at Sec.  721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a fish 
acute toxicity test, freshwater and marine (OPPTS Test Guideline 
850.1075); a fish acute toxicity test mitigated by humic acid (OPPTS 
Test Guideline 850.1085); an aquatic invertebrate acute toxicity test, 
freshwater daphnids (OPPTS Test Guideline 850.1010); and an algal 
toxicity test (OCSPP Test Guideline 850.4500) would help characterize 
the environmental effects of the PMN substances.
    CFR citation: 40 CFR 721.10512.

PMN Number P-07-599

    Chemical name: Aromatic acrylate monomer (generic).
    CAS number: Not available.
    Basis for action: The PMN states that the generic (non-
confidential) use of the substance will be in the production of 
polymers. Based on EcoSAR analysis of test data on analogous acrylates, 
EPA predicts toxicity to aquatic organisms may occur at concentrations 
that exceed 1 ppb of the PMN substance in surface waters. As described 
in the PMN, the substance is not expected to be released to surface 
waters. Therefore, EPA has not determined that the proposed 
manufacturing, processing, or use of the substance may present an 
unreasonable risk. EPA has determined, however, that any use of the 
substance resulting in surface water concentrations exceeding 1 ppb may 
cause significant adverse environmental effects. Based on this 
information, the PMN substance meets the concern criteria at Sec.  
721.170(b)(4)(ii).
    Recommended testing: EPA has determined that the results of a fish 
acute toxicity test, freshwater and marine (OPPTS Test Guideline 
850.1075); an aquatic invertebrate acute toxicity test, freshwater 
daphnids (OPPTS Test Guideline 850.1010); and an algal toxicity test 
(OCSPP Test Guideline 850.4500) would help characterize the 
environmental effects of the PMN substance.
    CFR citation: 40 CFR 721.10513.

[[Page 58686]]

PMN Number P-07-679

    Chemical name: [1,1'-Biphenyl]-2,2'-disulfonic acid, 4-[2-(4,5-
dihydro-3-methyl-5-oxo-1-phenyl-1H-pyrazol-4-yl)diazenyl]-4'-[2-(2-
hydroxy-1-naphthalenyl)diazenyl]-, sodium salt (1:2).
    CAS number: 6470-20-8.
    Basis for action: The PMN states that substance will be used as a 
dye for stationery ink. Based on SAR analysis of test data on analogs 
of an azo reduction product (pyrazole and methyl pyrazole), EPA 
identified concerns for liver, blood, and developmental toxicity; 
neurotoxicity; mutagenicity; and oncogenicity. As described in the PMN, 
inhalation exposures to workers and consumers are not expected as the 
PMN substance will be imported in rollerball pens and refills for 
rollerball pens. Therefore, EPA has not determined that the proposed 
processing or use of the substance may present an unreasonable risk. 
EPA has determined, however, that domestic manufacture, or any 
processing or use of the substance in the form of a solid may cause 
serious adverse health effects. Based on this information, the PMN 
substance meets the concern criteria at Sec.  721.170(b)(1)(i)(C) and 
(b)(3)(ii).
    Recommended testing: EPA has determined that the results of a 
bacterial reverse mutation test (OPPTS Test Guideline 870.5100); a 
mammalian erythrocyte micronucleus test (OPPTS Test Guideline 870.5395) 
via the intraperitoneal route; a repeated dose 28-day oral toxicity 
test (OPPTS Test Guideline 870.3050) in rodents; and an acute oral 
toxicity test (OPPTS Test Guideline 870.1100) would help characterize 
the human health effects of the PMN substance.
    CFR citation: 40 CFR 721.10514.

PMN Numbers P-10-58, P-10-59, and P-10-60

    Chemical name: Partially fluorinated alcohol substituted glycols 
(generic).
    CAS number: Not available.
    Effective date of TSCA section 5(e) consent order: October 8, 2010.
    Basis for TSCA section 5(e) consent order: The PMN states that the 
generic (non-confidential) uses of the PMN substances will be as an 
intermediate (P-10-58 and P-10-59) and a surface active agent (P-10-
60). EPA has concerns for potential incineration or other decomposition 
products of the PMN substances. These perfluorinated decomposition 
products may be released to the environment from incomplete 
incineration of the PMN substances at low temperatures. EPA has 
preliminary evidence, including data on some fluorinated polymers, that 
suggests that, under some conditions, the PMN substances could degrade 
in the environment. EPA has concerns that these degradation products 
will persist in the environment, could bioaccumulate or biomagnify, and 
could be toxic to people, wild mammals, and birds. These concerns are 
based on data on analog chemicals, including perfluorooctanoic acid 
(PFOA) and other perfluorinated alkyls, including the presumed 
environmental degradant. The order was issued under TSCA sections 
5(e)(1)(A)(i), 5(e)(1)(A)(ii)(I), and 5(e)(1)(A)(ii)(II), based on a 
finding that these substances may present an unreasonable risk of 
injury to the environment and human health, the substances may be 
produced in substantial quantities and may reasonably be anticipated to 
enter the environment in substantial quantities, and there may be 
significant (or substantial) human exposure to the substances and their 
potential degradation products. To protect against these exposures and 
risks, the consent order requires submission of testing on the PMN 
substance P-10-60 at five identified aggregate manufacture and 
importation volumes; requires analysis of raw materials; and restricts 
the use of P-10-58 and P-10-59 to use as intermediates to manufacture 
P-10-60. The SNUR designates as a ``significant new use'' the absence 
of these protective measures.
    Recommended testing: EPA has determined that the results of certain 
fate and physical/chemical property testing identified in the TSCA 
section 5(e) consent order would help characterize possible effects of 
the substances and their degradation products. The consent order 
contains five production volume limits. The PMN submitter has agreed 
not to exceed the confidential production volume limits without 
performing the specified testing on the PMN substance P-10-60. 
Additional testing is included in the preamble to the consent order, 
but this testing is not required at any specified time or production 
volume. However, the order's restrictions on manufacture, import, 
processing, distribution in commerce, use, and disposal of the PMN will 
remain in effect until the order is modified or revoked by EPA based on 
submission of that or other relevant information.
    CFR citation: 40 CFR 721.10515.

V. Rationale and Objectives of the Rule

A. Rationale

    During review of the PMNs submitted for the chemical substances 
that are subject to these SNURs, EPA concluded that for 8 of the 107 
chemical substances, regulation was warranted under TSCA section 5(e), 
pending the development of information sufficient to make reasoned 
evaluations of the health or environmental effects of the chemical 
substances. The basis for such findings is outlined in Unit IV. Based 
on these findings, TSCA section 5(e) consent orders requiring the use 
of appropriate exposure controls were negotiated with the PMN 
submitters. The SNUR provisions for these chemical substances are 
consistent with the provisions of the TSCA section 5(e) consent orders. 
These SNURs are promulgated pursuant to Sec.  721.160.
    In the other 99 cases, where the uses are not regulated under a 
TSCA section 5(e) consent order, EPA determined that one or more of the 
criteria of concern established at Sec.  721.170 were met, as discussed 
in Unit IV.

B. Objectives

    EPA is issuing these SNURs for specific chemical substances which 
have undergone premanufacture review because the Agency wants to 
achieve the following objectives with regard to the significant new 
uses designated in this rule:
     EPA will receive notice of any person's intent to 
manufacture, import, or process a listed chemical substance for the 
described significant new use before that activity begins.
     EPA will have an opportunity to review and evaluate data 
submitted in a SNUN before the notice submitter begins manufacturing, 
importing, or processing a listed chemical substance for the described 
significant new use.
     EPA will be able to regulate prospective manufacturers, 
importers, or processors of a listed chemical substance before the 
described significant new use of that chemical substance occurs, 
provided that regulation is warranted pursuant to TSCA sections 5(e), 
5(f), 6, or 7.
     EPA will ensure that all manufacturers, importers, and 
processors of the same chemical substance that is subject to a TSCA 
section 5(e) consent order are subject to similar requirements.
    Issuance of a SNUR for a chemical substance does not signify that 
the chemical substance is listed on the TSCA Inventory. Guidance on how 
to determine if a chemical substance is on the TSCA Inventory is 
available on the Internet at http://www.epa.gov/opptintr/existingchemicals/pubs/tscainventory/index.html.

[[Page 58687]]

VI. Direct Final Procedures

    EPA is issuing these SNURs as a direct final rule, as described in 
Sec.  721.160(c)(3) and Sec.  721.170(d)(4). In accordance with Sec.  
721.160(c)(3)(ii) and Sec.  721.170(d)(4)(i)(B), the effective date of 
this rule is November 20, 2012 without further notice, unless EPA 
receives written adverse or critical comments, or notice of intent to 
submit adverse or critical comments before October 22, 2012.
    If EPA receives written adverse or critical comments, or notice of 
intent to submit adverse or critical comments, on one or more of these 
SNURs before October 22, 2012, EPA will withdraw the relevant sections 
of this direct final rule before its effective date. EPA will then 
issue a proposed SNUR for the chemical substance(s) on which adverse or 
critical comments were received, providing a 30-day period for public 
comment.
    This rule establishes SNURs for a number of chemical substances. 
Any person who submits adverse or critical comments, or notice of 
intent to submit adverse or critical comments, must identify the 
chemical substance and the new use to which it applies. EPA will not 
withdraw a SNUR for a chemical substance not identified in the comment.

VII. Applicability of Rule to Uses Occurring Before Effective Date of 
the Rule

    Significant new use designations for a chemical substance are 
legally established as of the date of publication of this direct final 
rule (September 21, 2012).
    To establish a significant ``new'' use, EPA must determine that the 
use is not ongoing. The chemical substances subject to this rule have 
undergone premanufacture review. TSCA section 5(e) consent orders have 
been issued for eight chemical substances and the PMN submitters are 
prohibited by the TSCA section 5(e) consent orders from undertaking 
activities which EPA is designating as significant new uses. In cases 
where EPA has not received a notice of commencement (NOC) and the 
chemical substance has not been added to the TSCA Inventory, no other 
person may commence such activities without first submitting a PMN. For 
chemical substances for which an NOC has not been submitted at this 
time, EPA concludes that the uses are not ongoing. However, EPA 
recognizes that prior to the effective date of the rule, when chemical 
substances identified in this SNUR are added to the TSCA Inventory, 
other persons may engage in a significant new use as defined in this 
rule before the effective date of the rule. However, 67 of the 108 
chemical substances contained in this rule have CBI chemical 
identities, and since EPA has received a limited number of post-PMN 
bona fide submissions (per Sec. Sec.  720.25 and 721.11), the Agency 
believes that it is highly unlikely that any of the significant new 
uses described in the regulatory text of this rule are ongoing.
    As discussed in the Federal Register of April 24, 1990 (55 FR 
17376), EPA has decided that the intent of TSCA section 5(a)(1)(B) is 
best served by designating a use as a significant new use as of the 
date of publication of this direct final rule rather than as of the 
effective date of the rule. If uses begun after publication were 
considered ongoing rather than new, it would be difficult for EPA to 
establish SNUR notice requirements because a person could defeat the 
SNUR by initiating the significant new use before the rule became 
effective, and then argue that the use was ongoing before the effective 
date of the rule. Persons who begin commercial manufacture, import, or 
processing of the chemical substances regulated through this SNUR will 
have to cease any such activity before the effective date of this rule. 
To resume their activities, these persons would have to comply with all 
applicable SNUR notice requirements and wait until the notice review 
period, including any extensions, expires.
    EPA has promulgated provisions to allow persons to comply with this 
SNUR before the effective date. If a person meets the conditions of 
advance compliance under Sec.  721.45(h), the person is considered 
exempt from the requirements of the SNUR.

VIII. Test Data and Other Information

    EPA recognizes that TSCA section 5 does not require developing any 
particular test data before submission of a SNUN. The two exceptions 
are:
    1. Development of test data is required where the chemical 
substance subject to the SNUR is also subject to a test rule under TSCA 
section 4 (see TSCA section 5(b)(1)).
    2. Development of test data may be necessary where the chemical 
substance has been listed under TSCA section 5(b)(4) (see TSCA section 
5(b)(2)).
    In the absence of a TSCA section 4 test rule or a TSCA section 
5(b)(4) listing covering the chemical substance, persons are required 
only to submit test data in their possession or control and to describe 
any other data known to or reasonably ascertainable by them (see Sec.  
720.50). However, upon review of PMNs and SNUNs, the Agency has the 
authority to require appropriate testing. In cases where EPA issued a 
TSCA section 5(e) consent order that requires or recommends certain 
testing, Unit IV. describes those tests. Unit IV. also lists 
recommended testing for non-5(e) SNURs. Descriptions of tests are 
provided for informational purposes. EPA strongly encourages persons, 
before performing any testing, to consult with the Agency about 
protocol selection and test reporting. To access the harmonized test 
guidelines referenced in this document electronically, please go to 
http://www.epa.gov/ocspp and select ``Test Methods and Guidelines'' or 
for guidelines that are not currently available on the Web site EPA has 
placed a copy of that guideline in the public docket. The Organisation 
for Economic Co-operation and Development (OECD) test guidelines are 
available from the OECD Bookshop at http://www.oecdbookshop.org or 
SourceOECD at http://www.sourceoecd.org. The ASTM International 
standards are available at http://www.astm.org/Standard/index.shtml.
    In the TSCA section 5(e) consent orders for eight of the chemical 
substances regulated under this rule, EPA has established restrictions 
in view of the lack of data on the potential health and environmental 
risks that may be posed by the significant new uses or increased 
exposure to the chemical substances. These restrictions will not be 
removed until EPA determines that the unrestricted use will not present 
an unreasonable risk of injury, or result in significant or substantial 
exposure or environmental release. This determination is usually made 
based on the results of the required or recommended toxicity tests.
    The recommended tests specified in Unit IV. may not be the only 
means of addressing the potential risks of the chemical substance. 
However, submitting a SNUN without any test data may increase the 
likelihood that EPA will take action under TSCA section 5(e), 
particularly if satisfactory test results have not been obtained from a 
prior PMN or SNUN submitter. EPA recommends that potential SNUN 
submitters contact EPA early enough so that they will be able to 
conduct the appropriate tests.
    SNUN submitters should be aware that EPA will be better able to 
evaluate SNUNs which provide detailed information on the following:
     Human exposure and environmental release that may result 
from the significant new use of the chemical substances.

[[Page 58688]]

     Potential benefits of the chemical substances.
     Information on risks posed by the chemical substances 
compared to risks posed by potential substitutes.

IX. Procedural Determinations

    By this rule, EPA is establishing certain significant new uses 
which have been claimed as CBI subject to Agency confidentiality 
regulations at 40 CFR part 2 and 40 CFR part 720, subpart E. Absent a 
final determination or other disposition of the confidentiality claim 
under 40 CFR part 2 procedures, EPA is required to keep this 
information confidential. EPA promulgated a procedure to deal with the 
situation where a specific significant new use is CBI, at Sec.  
721.1725(b)(1).
    Under these procedures a manufacturer, importer, or processor may 
request that EPA determine whether a proposed use would be a 
significant new use under the rule. The manufacturer, importer, or 
processor must show that it has a bona fide intent to manufacture, 
import, or process the chemical substance and must identify the 
specific use for which it intends to manufacture, import, or process 
the chemical substance. If EPA concludes that the person has shown a 
bona fide intent to manufacture, import, or process the chemical 
substance, EPA will tell the person whether the use identified in the 
bona fide submission would be a significant new use under the rule. 
Since most of the chemical identities of the chemical substances 
subject to these SNURs are also CBI, manufacturers, importers, and 
processors can combine the bona fide submission under the procedure in 
Sec.  721.1725(b)(1) with that under Sec.  721.11 into a single step.
    If EPA determines that the use identified in the bona fide 
submission would not be a significant new use, i.e., the use does not 
meet the criteria specified in the rule for a significant new use, that 
person can manufacture, import, or process the chemical substance so 
long as the significant new use trigger is not met. In the case of a 
production volume trigger, this means that the aggregate annual 
production volume does not exceed that identified in the bona fide 
submission to EPA. Because of confidentiality concerns, EPA does not 
typically disclose the actual production volume that constitutes the 
use trigger. Thus, if the person later intends to exceed that volume, a 
new bona fide submission would be necessary to determine whether that 
higher volume would be a significant new use.

X. SNUN Submissions

    According to Sec.  721.1(c), persons submitting a SNUN must comply 
with the same notice requirements and EPA regulatory procedures as 
persons submitting a PMN, including submission of test data on health 
and environmental effects as described in Sec.  720.50. SNUNs must be 
submitted on EPA Form No. 7710-25, generated using e-PMN software, and 
submitted to the Agency in accordance with the procedures set forth in 
Sec. Sec.  721.25 and 720.40. E-PMN software is available 
electronically at http://www.epa.gov/opptintr/newchems.

XI. Economic Analysis

    EPA has evaluated the potential costs of establishing SNUN 
requirements for potential manufacturers, importers, and processors of 
the chemical substances subject to this rule. EPA's complete Economic 
Analysis is available in the docket under docket ID number EPA-HQ-OPPT-
2011-0941.

XII. Statutory and Executive Order Reviews

A. Executive Order 12866

    This rule establishes SNURs for several new chemical substances 
that were the subject of PMNs. The Office of Management and Budget 
(OMB) has exempted these types of actions from review under Executive 
Order 12866, entitled Regulatory Planning and Review (58 FR 51735, 
October 4, 1993).

B. Paperwork Reduction Act

    According to the Paperwork Reduction Act (PRA), 44 U.S.C. 3501 et 
seq., an Agency may not conduct or sponsor, and a person is not 
required to respond to a collection of information that requires OMB 
approval under PRA, unless it has been approved by OMB and displays a 
currently valid OMB control number. The OMB control numbers for EPA's 
regulations in title 40 of the CFR, after appearing in the Federal 
Register, are listed in 40 CFR part 9, and included on the related 
collection instrument or form, if applicable. EPA is amending the table 
in 40 CFR part 9 to list the OMB approval number for the information 
collection requirements contained in this rule. This listing of the OMB 
control numbers and their subsequent codification in the CFR satisfies 
the display requirements of PRA and OMB's implementing regulations at 5 
CFR part 1320. This Information Collection Request (ICR) was previously 
subject to public notice and comment prior to OMB approval, and given 
the technical nature of the table, EPA finds that further notice and 
comment to amend it is unnecessary. As a result, EPA finds that there 
is ``good cause'' under section 553(b)(3)(B) of the Administrative 
Procedure Act, 5 U.S.C. 553(b)(3)(B), to amend this table without 
further notice and comment.
    The information collection requirements related to this action have 
already been approved by OMB pursuant to PRA under OMB control number 
2070-0012 (EPA ICR No. 574). This action does not impose any burden 
requiring additional OMB approval. If an entity were to submit a SNUN 
to the Agency, the annual burden is estimated to average between 30 and 
170 hours per response. This burden estimate includes the time needed 
to review instructions, search existing data sources, gather and 
maintain the data needed, and complete, review, and submit the required 
SNUN.
    Send any comments about the accuracy of the burden estimate, and 
any suggested methods for minimizing respondent burden, including 
through the use of automated collection techniques, to the Director, 
Collection Strategies Division, Office of Environmental Information 
(2822T), Environmental Protection Agency, 1200 Pennsylvania Ave. NW., 
Washington, DC 20460-0001. Please remember to include the OMB control 
number in any correspondence, but do not submit any completed forms to 
this address.

C. Regulatory Flexibility Act

    On February 18, 2012, EPA certified pursuant to section 605(b) of 
the Regulatory Flexibility Act (RFA) (5 U.S.C. 601 et seq.), that 
promulgation of a SNUR does not have a significant economic impact on a 
substantial number of small entities where the following are true:
    1. A significant number of SNUNs would not be submitted by small 
entities in response to the SNUR.
    2. The SNUN submitted by any small entity would not cost 
significantly more than $8,300.
    A copy of that certification is available in the docket for this 
rule.
    This rule is within the scope of the February 18, 2012 
certification. Based on the Economic Analysis discussed in Unit XI. and 
EPA's experience promulgating SNURs (discussed in the certification), 
EPA believes that the following are true:
     A significant number of SNUNs would not be submitted by 
small entities in response to the SNUR.
     Submission of the SNUN would not cost any small entity 
significantly more than $8,300.
    Therefore, the promulgation of the SNUR would not have a 
significant

[[Page 58689]]

economic impact on a substantial number of small entities.

D. Unfunded Mandates Reform Act

    Based on EPA's experience with proposing and finalizing SNURs, 
State, local, and Tribal governments have not been impacted by these 
rulemakings, and EPA does not have any reasons to believe that any 
State, local, or Tribal government will be impacted by this rule. As 
such, EPA has determined that this rule does not impose any enforceable 
duty, contain any unfunded mandate, or otherwise have any effect on 
small governments subject to the requirements of sections 202, 203, 
204, or 205 of the Unfunded Mandates Reform Act of 1995 (UMRA) (Pub. L. 
104-4).

E. Executive Order 13132

    This action will not have a substantial direct effect on States, on 
the relationship between the national government and the States, or on 
the distribution of power and responsibilities among the various levels 
of government, as specified in Executive Order 13132, entitled 
Federalism (64 FR 43255, August 10, 1999).

F. Executive Order 13175

    This rule does not have Tribal implications because it is not 
expected to have substantial direct effects on Indian Tribes. This rule 
does not significantly nor uniquely affect the communities of Indian 
Tribal governments, nor does it involve or impose any requirements that 
affect Indian Tribes. Accordingly, the requirements of Executive Order 
13175, entitled Consultation and Coordination with Indian Tribal 
Governments (65 FR 67249, November 9, 2000), do not apply to this rule.

G. Executive Order 13045

    This action is not subject to Executive Order 13045, entitled 
Protection of Children from Environmental Health Risks and Safety Risks 
(62 FR 19885, April 23, 1997), because this is not an economically 
significant regulatory action as defined by Executive Order 12866, and 
this action does not address environmental health or safety risks 
disproportionately affecting children.

H. Executive Order 13211

    This action is not subject to Executive Order 13211, entitled 
Actions Concerning Regulations That Significantly Affect Energy Supply, 
Distribution, or Use (66 FR 28355, May 22, 2001), because this action 
is not expected to affect energy supply, distribution, or use and 
because this action is not a significant regulatory action under 
Executive Order 12866.

I. National Technology Transfer and Advancement Act

    In addition, since this action does not involve any technical 
standards, section 12(d) of the National Technology Transfer and 
Advancement Act of 1995 (NTTAA), Public Law 104-113, section 12(d) (15 
U.S.C. 272 note), does not apply to this action.

J. Executive Order 12898

    This action does not entail special considerations of environmental 
justice related issues as delineated by Executive Order 12898, entitled 
Federal Actions to Address Environmental Justice in Minority 
Populations and Low-Income Populations (59 FR 7629, February 16, 1994).

XIII. Congressional Review Act

    The Congressional Review Act, 5 U.S.C. 801 et seq., generally 
provides that before a rule may take effect, the agency promulgating 
the rule must submit a rule report, which includes a copy of the rule, 
to each House of the Congress and the Comptroller General of the United 
States. EPA will submit a report containing this rule and other 
required information to the U.S. Senate, the U.S. House of 
Representatives, and the Comptroller General of the United States prior 
to publication of the rule in the Federal Register. This rule is not a 
``major rule'' as defined by 5 U.S.C. 804(2).

List of Subjects

40 CFR Part 9

    Environmental protection, Reporting and recordkeeping requirements.

40 CFR Part 721

    Environmental protection, Chemicals, Hazardous substances, 
Reporting and recordkeeping requirements.

    Dated: September 13, 2012.
Maria J. Doa,
Director, Chemical Control Division, Office of Pollution Prevention and 
Toxics.

    Therefore, 40 CFR parts 9 and 721 are amended as follows:

PART 9--[AMENDED]

0
1. The authority citation for part 9 continues to read as follows:

    Authority:  7 U.S.C. 135 et seq., 136-136y; 15 U.S.C. 2001, 
2003, 2005, 2006, 2601-2671; 21 U.S.C. 331j, 346a, 348; 31 U.S.C. 
9701; 33 U.S.C. 1251 et seq., 1311, 1313d, 1314, 1318, 1321, 1326, 
1330, 1342, 1344, 1345(d) and (e), 1361; E.O. 11735, 38 FR 21243, 3 
CFR, 1971-1975 Comp. p. 973; 42 U.S.C. 241, 242b, 243, 246, 300f, 
300g, 300g-1, 300g-2, 300g-3, 300g-4, 300g-5, 300g-6, 300j-1, 300j-
2, 300j-3, 300j-4, 300j-9, 1857 et seq., 6901-6992k, 7401-7671q, 
7542, 9601-9657, 11023, 11048.

0
2. In Sec.  14;9.1, add the following sections in numerical order under 
the undesignated center heading ``Significant New Uses of Chemical 
Substances'' to read as follows:

Sec.  [emsp14]9.1  OMB approvals under the Paperwork Reduction Act.

* * * * *

------------------------------------------------------------------------
                                                                 OMB
                      40 CFR citation                        Control No.
------------------------------------------------------------------------
 
                                * * * * *
               Significant New Uses of Chemical Substances
 
                                * * * * *
721.10427..................................................    2070-0012
721.10428..................................................    2070-0012
721.10429..................................................    2070-0012
721.10430..................................................    2070-0012
721.10431..................................................    2070-0012
721.10432..................................................    2070-0012
721.10433..................................................    2070-0012
721.10434..................................................    2070-0012
721.10435..................................................    2070-0012
721.10436..................................................    2070-0012
721.10437..................................................    2070-0012
721.10438..................................................    2070-0012
721.10439..................................................    2070-0012
721.10440..................................................    2070-0012
721.10441..................................................    2070-0012
721.10442..................................................    2070-0012
721.10443..................................................    2070-0012
721.10444..................................................    2070-0012
721.10445..................................................    2070-0012
721.10446..................................................    2070-0012
721.10447..................................................    2070-0012
721.10448..................................................    2070-0012
721.10449..................................................    2070-0012
721.10450..................................................    2070-0012
721.10451..................................................    2070-0012
721.10452..................................................    2070-0012
721.10453..................................................    2070-0012
721.10454..................................................    2070-0012
721.10455..................................................    2070-0012
721.10456..................................................    2070-0012
721.10457..................................................    2070-0012
721.10458..................................................    2070-0012
721.10459..................................................    2070-0012
721.10460..................................................    2070-0012
721.10461..................................................    2070-0012
721.10462..................................................    2070-0012
721.10463..................................................    2070-0012
721.10464..................................................    2070-0012
721.10465..................................................    2070-0012
721.10466..................................................    2070-0012
721.10467..................................................    2070-0012
721.10468..................................................    2070-0012
721.10469..................................................    2070-0012
721.10470..................................................    2070-0012
721.10471..................................................    2070-0012
721.10472..................................................    2070-0012
721.10473..................................................    2070-0012
721.10474..................................................    2070-0012
721.10475..................................................    2070-0012
721.10476..................................................    2070-0012
721.10477..................................................    2070-0012

[[Page 58690]]

 
721.10478..................................................    2070-0012
721.10479..................................................    2070-0012
721.10480..................................................    2070-0012
721.10481..................................................    2070-0012
721.10482..................................................    2070-0012
721.10483..................................................    2070-0012
721.10484..................................................    2070-0012
721.10485..................................................    2070-0012
721.10486..................................................    2070-0012
721.10487..................................................    2070-0012
721.10488..................................................    2070-0012
721.10489..................................................    2070-0012
721.10490..................................................    2070-0012
721.10491..................................................    2070-0012
721.10492..................................................    2070-0012
721.10493..................................................    2070-0012
721.10494..................................................    2070-0012
721.10495..................................................    2070-0012
721.10496..................................................    2070-0012
721.10497..................................................    2070-0012
721.10498..................................................    2070-0012
721.10499..................................................    2070-0012
721.10500..................................................    2070-0012
721.10501..................................................    2070-0012
721.10502..................................................    2070-0012
721.10503..................................................    2070-0012
721.10504..................................................    2070-0012
721.10505..................................................    2070-0012
721.10506..................................................    2070-0012
721.10507..................................................    2070-0012
721.10508..................................................    2070-0012
721.10509..................................................    2070-0012
721.10510..................................................    2070-0012
721.10511..................................................    2070-0012
721.10512..................................................    2070-0012
721.10513..................................................    2070-0012
721.10514..................................................    2070-0012
721.10515..................................................    2070-0012
 
                                 * * * *
------------------------------------------------------------------------

* * * * *

PART 721--[AMENDED]

0
3. The authority citation for part 721 continues to read as follows:

    Authority:  15 U.S.C. 2604, 2607, and 2625(c).

0
4. Add Sec.  721.10427 to subpart E to read as follows:

Sec.  721.10427  Aminoalkanol (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
aminoalkanol (PMN P-96-308) is subject to reporting under this section 
for the significant new uses described in paragraph (a)(2) of this 
section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(j).
    (ii) Release to water. Requirements as specified in Sec.  
721.90(a)(4), (b)(4), and (c)(4) (N=600).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), (i), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.
    (3) Determining whether a specific use is subject to this section. 
The provisions of Sec.  721.1725(b)(1) apply to paragraph (a)(2)(i) of 
this section.

0
5. Add Sec.  721.10428 to subpart E to read as follows:

Sec.  721.10428  Fatty acids, C18-unsatd., dimers, reaction products 
with 1-piperazineethanamine.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as fatty acids, 
C18-unsatd., dimers, reaction products with 1-
piperazineethanamine (PMN P-96-1021; CAS No. 206565-90-4) is subject to 
reporting under this section for the significant new uses described in 
paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec.  
721.90(a)(4), (b)(4), and (c)(4) (N=1).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
6. Add Sec.  721.10429 to subpart E to read as follows:

Sec.  721.10429  Fatty acids, C18-unsatd., dimers, reaction products 
with 1-piperazineethanamine and tall-oil fatty acids.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as fatty acids, 
C18-unsatd., dimers, reaction products with 1-
piperazineethanamine and tall-oil fatty acids (PMN P-96-1022; CAS No. 
206565-89-1) is subject to reporting under this section for the 
significant new uses described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec.  
[emsp14]721.90(a)(4), (b)(4), and (c)(4) (N=1).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
7. Add Sec.  721.10430 to subpart E to read as follows:

Sec.  [emsp14]721.10430  Tetra alkyl ammonium salt (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as tetra 
alkyl ammonium salt (PMN P-97-823) is subject to reporting under this 
section for the significant new uses described in paragraph (a)(2) of 
this section.
    (2) The significant new uses are:
    (i) Hazard communication program. Requirements as specified in 
Sec.  721.72(a) and (c)(2) (the following statement must be included in 
the material safety data sheet (MSDS): ``The results of an eye 
irritation test in rabbits resulted in deaths at levels of the PMN 
substance greater than 25 percent concentration'').
    (ii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(j) (use of the substance as described in 
the PMN at concentrations less than or equal to 25 percent).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), (f), (h), and (i) and are applicable to 
manufacturers, importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.
    (3) Determining whether a specific use is subject to this section. 
The provisions of Sec.  721.1725(b)(1) apply to paragraph (a)(2)(ii) of 
this section.
0
8. Add Sec.  721.10431 to subpart E to read as follows:

Sec.  721.10431  Phosphoric acid esters (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substances identified generically as 
phosphoric acid esters

[[Page 58691]]

(PMNs P-98-141 and P-98-142) are subject to reporting under this 
section for the significant new uses described in paragraph (a)(2) of 
this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec.  
721.90(a)(4), (b)(4), and (c)(4) (N=100).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of these substances.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
9. Add Sec.  [emsp14]721.10432 to subpart E to read as follows:

Sec.  [emsp14]721.10432  1,2,4,5,7,8-Hexoxonane, 3,6,9-triethyl-3,6,9-
trimethyl-.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as 1,2,4,5,7,8-
hexoxonane, 3,6,9-triethyl-3,6,9-trimethyl-. (PMN P-98-1028; CAS No. 
24748-23-0) is subject to reporting under this section for the 
significant new uses described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(j) (viscosity modifier in the manufacture 
of polypropylene manufactured and supplied as a solution in at least 40 
percent mineral spirits).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
10. Add Sec.  [emsp14]721.10433 to subpart E to read as follows:

Sec.  [emsp14]721.10433  Cyclopentene, 1,2,3,3,4,4,5,5-octafluoro-.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as cyclopentene, 
1,2,3,3,4,4,5,5-octafluoro- (PMN P-99-184; CAS No. 559-40-0) is subject 
to reporting under this section for the significant new uses described 
in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(f) and (j) (dry etching agent and chemical 
vapor deposition agent for the production of semiconductors).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
11. Add Sec.  [emsp14]721.10434 to subpart E to read as follows:

Sec.  [emsp14]721.10434  Cyclopentane, 1,1,2,2,3,3,4-heptafluoro-.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as cyclopentane, 
1,1,2,2,3,3,4-heptafluoro- (PMN P-99-214; CAS No. 15290-77-4) is 
subject to reporting under this section for the significant new uses 
described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(f), (j) (solvent and a cleaning and drying 
agent), and (o).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
12. Add Sec.  [emsp14]721.10435 to subpart E to read as follows:

Sec.  [emsp14]721.10435  Phenol, 2-(1-methyl-1-phenylethyl)-4-(1,1,3,3-
tetramethylbutyl)-.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as phenol, 2-(1-
methyl-1-phenylethyl)-4-(1,1,3,3-tetramethylbutyl)- (PMN P-99-1179; CAS 
No. 73936-80-8) is subject to reporting under this section for the 
significant new uses described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec.  
721.90(a)(4), (b)(4), and (c)(4) (N=1).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
13. Add Sec.  721.10436 to subpart E to read as follows:

Sec.  721.10436  Amine neutralized phosphated polyesters (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substances identified generically as amine 
neutralized phosphated polyesters (PMN P-99-1217 and P-99-1218) are 
subject to reporting under this section for the significant new uses 
described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(s) (50,000 kilograms combined for the 
substances identified in PMNs P-99-1217 and P-99-1218).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of these substances.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
14. Add Sec.  721.10437 to subpart E to read as follows:

Sec.  721.10437  Sulfonic acid, linear xylene alkylate, mono, sodium 
salts (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substances identified generically as 
sulfonic acid, linear xylene alkylate, mono, sodium salts (PMNs P-99-
1280, P-99-1281, and P-99-1282) are subject to reporting under this 
section for the significant new uses described in paragraph (a)(2) of 
this section.
    (2) The significant new uses are:

[[Page 58692]]

    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(j) (enhanced oil recovery surfactants).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of these substances.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
15. Add Sec.  721.10438 to subpart E to read as follows:

Sec.  721.10438  Dialkyl hydroxybenzenealkanoic acid ester (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as dialkyl 
hydroxybenzenealkanoic acid ester (PMN P-00-346) is subject to 
reporting under this section for the significant new uses described in 
paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1), (a)(3), (b) (concentration set at 1.0 percent), and (c).
    (ii) Hazard communication program. Requirements as specified in 
Sec.  721.72(a), (b), (c), (d), (e) (concentration set at 1.0 percent), 
(f), (g)(1)(iv), (g)(2)(i), (g)(2)(v), and (g)(5).
    (iii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(q).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (i) are applicable to manufacturers, importers, and 
processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.
    (3) Determining whether a specific use is subject to this section. 
The provisions of Sec.  721.1725(b)(1) apply to paragraph (a)(2)(iii) 
of this section.

0
16. Add Sec.  721.10439 to subpart E to read as follows:

Sec.  721.10439  1,3-Dioxolan-2-one, 4-ethenyl.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as 1,3-dioxolan-2-one, 
4-ethenyl (PMN P-00-635; CAS No. 4427-96-7) is subject to reporting 
under this section for the significant new uses described in paragraph 
(a)(2) of this section.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1), (a)(3), (b) (concentration set at 0.1 percent), and (c).
    (ii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(j).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (e), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.
    (3) Determining whether a specific use is subject to this section. 
The provisions of Sec.  721.1725(b)(1) apply to paragraph (a)(2)(ii) of 
this section.

0
17. Add Sec.  721.10440 to subpart E to read as follows:

Sec.  721.10440  Diphosphoric acid, polymers with ethoxylated reduced 
Me esters of reduced polymd. oxidized tetrafluoroethylene.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as diphosphoric acid, 
polymers with ethoxylated reduced Me esters of reduced polymd. oxidized 
tetrafluoroethylene (PMN P-00-1165; CAS No. 200013-65-6) is subject to 
reporting under this section for the significant new uses described in 
paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(o) and (y)(1).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
18. Add Sec.  721.10441 to subpart E to read as follows:

Sec.  721.10441  1,2-Benzenedicarboxylic acid, di-C7-14-branched and 
linear alkyl esters.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as 1,2-
benzenedicarboxylic acid, di-C7-14-branched and linear alkyl 
esters (PMN P-01-382; CAS No. 309934-68-7) is subject to reporting 
under this section for the significant new uses described in paragraph 
(a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(o) (use as plasticizers for flexible 
polyvinyl chloride not to include children's toys (e.g., pacifiers, 
rattles, and teethers)).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
19. Add Sec.  721.10442 to subpart E to read as follows:

Sec.  721.10442  1,2-Benzenedicarboxylic acid, di-C6-14-branched and 
linear alkyl esters.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as 1,2-
benzenedicarboxylic acid, di-C6-14-branched and linear alkyl 
esters (PMN P-01-383; CAS No. 309934-69-8) is subject to reporting 
under this section for the significant new uses described in paragraph 
(a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(o) (use as plasticizers for flexible 
polyvinyl chloride not to include children's toys (e.g., pacifiers, 
rattles, and teethers)).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
20. Add Sec.  721.10443 to subpart E to read as follows:

[[Page 58693]]

Sec.  721.10443  Ethoxylated alkylphenol sulfate, ammonium salt 
(generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
ethoxylated alkylphenol sulfate, ammonium salt (PMN P-01-470) is 
subject to reporting under this section for the significant new uses 
described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(k) (manufacture and import of the PMN 
substance according to the chemical composition section of the consent 
order where the substance must have either a mean number of moles of 
ethoxy groups greater than or equal to 10, or the average number 
molecular weight is greater than 950 daltons).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
21. Add Sec.  721.10444 to subpart E to read as follows:

Sec.  721.10444  Propanol, mercapto-.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as propanol, mercapto- 
(PMN P-01-499; CAS No. 63947-56-8) is subject to reporting under this 
section for the significant new uses described in paragraph (a)(2) of 
this section.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1), (a)(3), (b) (concentration set at 1.0 percent), and (c).
    (ii) Release to water. Requirements as specified in Sec.  
721.90(a)(4), (b)(4), and (c)(4) (N=11).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (e) and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
22. Add Sec.  721.10445 to subpart E to read as follows:

Sec.  721.10445  2-Propen-1-ol, reaction products with hydrogen 
sulfide, distn. residues.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as 2-propen-1-ol, 
reaction products with hydrogen sulfide, distn. residues (PMN P-01-500; 
CAS No. 374078-75-8) is subject to reporting under this section for the 
significant new uses described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1), (a)(3), (b) (concentration set at 1.0 percent), and (c).
    (ii) Release to water. Requirements as specified in Sec.  
721.90(a)(4), (b)(4), and (c)(4) (N=1).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (e) and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
23. Add Sec.  721.10446 to subpart E to read as follows:

Sec.  721.10446  1, 9-Cyclohexadecadiene.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as 1,9-
cyclohexadecadiene (PMN P-01-762; CAS No. 4277-06-9) is subject to 
reporting under this section for the significant new uses described in 
paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1), (a)(3), (b) (concentration set at 1.0 percent), and (c).
    (ii) Release to water. Requirements as specified in Sec.  
721.90(a)(4), (b)(4), and (c)(4) (N=1).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (e) and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
24. Add Sec.  721.10447 to subpart E to read as follows:

Sec.  721.10447  17-Oxabicyclo[14.1.0]heptadec-8-ene.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as 17-
oxabicyclo[14.1.0]heptadec-8-ene (PMN P-01-829; CAS No. 34748-97-5) is 
subject to reporting under this section for the significant new uses 
described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1), (a)(3), (a)(4) (National Institute for Occupational 
Safety and Health (NIOSH)-certified air purifying respirator equipped 
with a high efficiency particulate filter including disposable 
cartridge), (a)(5)(vii), (b) (concentration set at 1.0 percent), and 
(c).
    (ii) Release to water. Requirement as specified in Sec.  
721.90(a)(4), (b)(4), and (c)(4) (N=1).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (e) and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
25. Add Sec.  721.10448 to subpart E to read as follows:

Sec.  721.10448  Acetic acid, hydroxy- methoxy-, methyl ester, reaction 
products with substituted alkylamine (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as acetic 
acid, hydroxymethoxy-, methyl ester, reaction products with substituted 
alkylamine (PMN P-02-120) is subject to reporting under this section 
for the significant new uses described in paragraph (a)(2) of this 
section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(k) (manufacture and import of the PMN 
substance according to the average number molecular weight section of 
the consent order where the average molecular weight is greater than or 
equal to 850 daltons).
    (ii) [Reserved]

[[Page 58694]]

    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
26. Add Sec.  721.10449 to subpart E to read as follows:

Sec.  721.10449  Aromatic polyester polyol (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
aromatic polyester polyol (PMN P-02-172) is subject to reporting under 
this section for the significant new uses described in paragraph (a)(2) 
of this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec.  
721.90(a)(4), (b)(4), and (c)(4) (N=40).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
27. Add Sec.  721.10450 to subpart E to read as follows:

Sec.  [emsp14]721.10450  Oxirane, 2-[[3-
(trimethoxysilyl)propoxy]methyl]-, reaction products with wollastonite 
(Ca(SiO3)).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as oxirane, 2-[[3-
(trimethoxysilyl)propoxy]methyl]-, reaction products with wollastonite 
(Ca(SiO3)) (PMN P-02-285; CAS No. 100402-91-3) is subject to 
reporting under this section for the significant new uses described in 
paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(k) (manufacture and process the PMN 
substance with an average number aspect ratio no greater than 5, and no 
more than 15 percent of the PMN substance shall have an aspect ratio 
greater than 10).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
28. Add Sec.  721.10451 to subpart E to read as follows:

Sec.  721.10451  Alkyd amide polyol (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as alkyd 
amide polyol (PMN P-02-436) is subject to reporting under this section 
for the significant new uses described in paragraph (a)(2) of this 
section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec.  
721.90(a)(4), (b)(4), and (c)(4) (N=3).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
29. Add Sec.  721.10452 to subpart E to read as follows:

Sec.  721.10452  9-Octadecenoic acid (9Z)-, 1,1'-(dimethylstannylene) 
ester.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as 9-octadecenoic acid 
(9Z)-, 1,1'-(dimethylstannylene) ester (PMN P-02-659; CAS No. 3865-34-
7) is subject to reporting under this section for the significant new 
uses described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec.  
721.90(a)(4), (b)(4), and (c)(4) (N=10).
    (ii) [Reserved].
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
30. Add Sec.  721.10453 to subpart E to read as follows:

Sec.  721.10453  Polyglycerin alkyl ether (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
polyglycerin alkyl ether (PMN P-02-796) is subject to reporting under 
this section for the significant new uses described in paragraph (a)(2) 
of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(j).
    (ii) [Reserved].
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.
    (3) Determining whether a specific use is subject to this section. 
The provisions of Sec.  721.1725(b)(1) apply to paragraph (a)(2)(i) of 
this section.

0
31. Add Sec.  721.10454 to subpart E to read as follows:

Sec.  721.10454  Propoxylated ethoxylated alkylamine (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
propoxylated ethoxylated alkylamine (PMN P-02-828) is subject to 
reporting under this section for the significant new uses described in 
paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec.  
721.90(a)(4), (b)(4), and (c)(4) (N=80).
    (ii) [Reserved].
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this substance.

[[Page 58695]]

    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
32. Add Sec.  721.10455 to subpart E to read as follows:

Sec.  721.10455  Oxirane, 2,2',2''-[ethylidynetris(4,1-
phenyleneoxymethylene)]tris-.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as oxirane, 2,2',2''-
[ethylidynetris(4,1-phenyleneoxymethylene)]tris- (PMN P-03-61; CAS No. 
87093-13-8) is subject to reporting under this section for the 
significant new uses described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(y)(1).
    (ii) [Reserved].
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
33. Add Sec.  721.10456 to subpart E to read as follows:

Sec.  721.10456  Tristyryl phenol alkoxylate salt (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
tristyryl phenol alkoxylate salt (PMN P-03-104) is subject to reporting 
under this section for the significant new uses described in paragraph 
(a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(j).
    (ii) [Reserved].
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.
    (3) Determining whether a specific use is subject to this section. 
The provisions of Sec.  721.1725(b)(1) apply to paragraph (a)(2)(i) of 
this section.
0
34. Add Sec.  721.10457 to subpart E to read as follows:

Sec.  721.10457  1,2-Benzenedicarboxylic acid, mixed esters with benzyl 
alc., cyclohexanol, 2-ethyl-1-hexanol, fumaric acid and propylene 
glycol.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as 1,2-
benzenedicarboxylic acid, mixed esters with benzyl alc., cyclohexanol, 
2-ethyl-1-hexanol, fumaric acid and propylene glycol (PMN P-03-154; CAS 
No. 464920-01-2) is subject to reporting under this section for the 
significant new uses described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec.  
721.90(a)(4), (b)(4), and (c)(4) (N=1).
    (ii) [Reserved].
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
35. Add Sec.  721.10458 to subpart E to read as follows:

Sec.  721.10458  Acrylate of hydroxyimide (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
acrylate of hydroxyimide (PMN P-03-238) is subject to reporting under 
this section for the significant new uses described in paragraph (a)(2) 
of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(v)(2), (w)(2), and (x)(2).
    (ii) Release to water. Requirements as specified in Sec.  
721.90(a)(4), (b)(4), and (c)(4) (N=20).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), (i), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
36. Add Sec.  721.10459 to subpart E to read as follows:

Sec.  721.10459  Amino-substituted carbopolycycle (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as amino-
substituted carbopolycycle (PMN P-03-282) is subject to reporting under 
this section for the significant new uses described in paragraph (a)(2) 
of this section.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1), (a)(2)(i), (a)(3), (a)(4) (respirators must provide a 
National Institute for Occupational Safety and Health (NIOSH) assigned 
protection factor of at least 50), (a)(6), (b) (concentration set at 
0.1 percent), and (c). Best's Viton model 878, Best's Butyl model 878, 
Barrier Laminated Film, and PVA Supported Polyvinyl Alcohol have been 
demonstrated to satisfy the requirements of Sec.  721.63(a)(3)(i). 
Other demonstrated impervious gloves that satisfy Sec.  721.63(a)(3)(i) 
are permissible. The following respirators meet the minimum 
requirements of Sec.  721.63(a)(4): NIOSH-certified air-purifying, 
tight-fitting, half-face respirator equipment with N100 (if oil 
aerosols absent), R100, or P100 filters; NIOSH-certified air-purifying, 
tight-fitting full-face respirator with N100 (if oil aerosols absent), 
R100, or P100 filters; NIOSH-certified powered air-purifying respirator 
equipped with a loose-fitting hood or helmet and high efficiency 
particulate air (HEPA) filters; NIOSH-certified powered air-purifying 
respirator equipped with a tight-fitting facepiece (either half-face or 
full-face) and HEPA filters; or NIOSH-certified supplied-air respirator 
operated in pressure demand or continuous flow mode and equipped with a 
hood or helmet, or tight-fitting facepiece (either half-face or full-
face).
    (ii) Hazard communication program. Requirements as specified in 
Sec.  721.72(a), (b), (c), (d), (e) (concentration set at 0.1 percent), 
(f), (g)(1)(i), (g)(1)(vii), and (g)(2).
    (iii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(f) and (j).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (i) are applicable to

[[Page 58696]]

manufacturers, importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.
    (3) Determining whether a specific use is subject to this section. 
The provisions of Sec.  721.1725(b)(1) apply to paragraph (a)(2)(iii) 
of this section.

0
37. Add Sec.  721.10460 to subpart E to read as follows:

Sec.  721.10460  Azo nickel complex (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as azo 
nickel complex (PMN P-03-307) is subject to reporting under this 
section for the significant new uses described in paragraph (a)(2) of 
this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(j), (v)(1), (w)(1), and (x)(1).
    (ii) [Reserved].
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.
    (3) Determining whether a specific use is subject to this section. 
The provisions of Sec.  721.1725(b)(1) apply to paragraph (a)(2)(i) of 
this section.

0
38. Add Sec.  721.10461 to subpart E to read as follows:

Sec.  721.10461  Oxazolidine, 3,3'-methylenebis[5-methyl-.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as oxazolidine, 3,3'-
methylenebis[5-methyl- (PMN P-03-325; CAS No. 66204-44-2) is subject to 
reporting under this section for the significant new uses described in 
paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(j) (metalworking fluid).
    (ii) Release to water. Requirements as specified in Sec.  
721.90(a)(4), (b)(4), and (c)(4) (N=40 (saltwater) and N=100 
(freshwater)).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), (i), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
39. Add Sec.  721.10462 to subpart E to read as follows:

Sec.  721.10462  1-Penten-3-one, 1-(4-chlorophenyl)-4,4-dimethyl-.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as 1-penten-3-one, 1-
(4-chlorophenyl)-4,4-dimethyl- (PMN P-03-354; CAS No. 1577-03-3) is 
subject to reporting under this section for the significant new uses 
described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(g).
    (ii) Release to water. Requirements as specified in Sec.  
721.90(a)(4), (b)(4), and (c)(4) (N=30).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), (i), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
40. Add Sec.  721.10463 to subpart E to read as follows:

Sec.  721.10463  Fatty acid amides (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as fatty 
acid amides (PMN P-03-388) is subject to reporting under this section 
for the significant new uses described in paragraph (a)(2) of this 
section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(j).
    (ii) [Reserved].
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.
    (3) Determining whether a specific use is subject to this section. 
The provisions of Sec.  721.1725(b)(1) apply to paragraph (a)(2)(i) of 
this section.

0
41. Add Sec.  721.10464 to subpart E to read as follows:

Sec.  721.10464  Fatty acid, reaction products with alkanolamine 
(generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as fatty 
acid, reaction products with alkanolamine (PMN P-03-461) is subject to 
reporting under this section for the significant new uses described in 
paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(j).
    (ii) [Reserved].
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.
    (3) Determining whether a specific use is subject to this section. 
The provisions of Sec.  721.1725(b)(1) apply to paragraph (a)(2)(i) of 
this section.

0
42. Add Sec.  721.10465 to subpart E to read as follows:

Sec.  721.10465  2-Propenoic acid, 2-methyl-, 3-
hydroxytricyclo[3.3.1.13,7]dec-1-yl ester.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as 2-propenoic acid, 
2-methyl-, 3-hydroxytricyclo[3.3.1.13,7]dec-1-yl ester (PMN P-03-561; 
CAS No. 115372-36-6) is subject to reporting under this section for the 
significant new uses described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1), (a)(2)(i), (a)(2)(iii), (a)(3), (a)(4) (National 
Institute for Occupational Safety and Health (NIOSH)-certified 
respirator with an assigned protection factor (APF) of at least 10), 
(a)(6)(i), (a)(6)(ii), (a)(6)(v),

[[Page 58697]]

(a)(6)(vi), (b) (concentration set at 1.0 percent), and (c).
    (ii) Release to water. Requirements as specified in Sec.  
721.90(a)(4), (b)(4), and (c)(4) (N=3).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (e) and (k) and are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
43. Add Sec.  721.10466 to subpart E to read as follows:

Sec.  721.10466  2-Propenoic acid, 2-methyl-, 2-
ethyltricyclo[3.3.1.13,7]dec-2-yl ester.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as 2-propenoic acid, 
2-methyl-, 2-ethyltricyclo[3.3.1.13,7]dec-2-yl ester (PMN P-03-563; CAS 
No. 209982-56-9) is subject to reporting under this section for the 
significant new uses described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1), (a)(2)(i), (a)(2)(iii), (a)(3), (a)(4) (National 
Institute for Occupational Safety and Health (NIOSH)-certified 
respirator with an assigned protection factor (APF) of at least 10), 
(a)(6)(i), (a)(6)(ii), (a)(6)(v), (a)(6)(vi), (b) (concentration set at 
1.0 percent), and (c).
    (ii) Release to water. Requirements as specified in Sec.  
721.90(a)(4), (b)(4), and (c)(4) (N=3).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (e) and (k) and are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
44. Add Sec.  721.10467 to subpart E to read as follows:

Sec.  [emsp14]721.10467  2-Propenoic acid, 3-
hydroxytricyclo[3.3.1.13,7]dec-1-yl ester.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as 2-propenoic acid, 
3-hydroxytricyclo[3.3.1.13,7]dec-1-yl ester (PMN P-03-564; CAS No. 
216581-76-9) is subject to reporting under this section for the 
significant new uses described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1), (a)(2)(i), (a)(2)(iii), (a)(3), (a)(4) (National 
Institute for Occupational Safety and Health (NIOSH)-certified 
respirator with an assigned protection factor (APF) of at least 10), 
(a)(6)(i), (a)(6)(ii), (a)(6)(v), (a)(6)(vi), (b) (concentration set at 
1.0 percent), and (c).
    (ii) Release to water. Requirements as specified in Sec.  
721.90(a)(4), (b)(4), and (c)(4) (N=3).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (e) and (k) and are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
45. Add Sec.  721.10468 to subpart E to read as follows:

Sec.  [emsp14]721.10468  2-Propenoic acid, 2-
methyltricyclo[3.3.1.13,7]dec-2-yl ester.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as 2-propenoic acid, 
2-methyltricyclo[3.3.1.13,7]dec-2-yl ester (PMN P-03-565; CAS No. 
249562-06-9) is subject to reporting under this section for the 
significant new uses described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1), (a)(2)(i), (a)(2)(iii), (a)(3), (a)(4) (National 
Institute for Occupational Safety and Health (NIOSH)-certified 
respirator with an assigned protection factor (APF) of at least 10), 
(a)(6)(i), (a)(6)(ii), (a)(6)(v), (a)(6)(vi), (b) (concentration set at 
1.0 percent), and (c).
    (ii) Release to water. Requirements as specified in Sec.  
721.90(a)(4), (b)(4), and (c)(4) (N=3).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (e) and (k) and are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
46. Add Sec.  [emsp14]721.10469 to subpart E to read as follows:

Sec.  721.10469  2-Propenoic acid, 2-ethyltricyclo[3.3.1.13,7]dec-2-yl 
ester.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as 2-propenoic acid, 
2-ethyltricyclo[3.3.1.13,7]dec-2-yl ester (PMN P-03-566; CAS No. 
303186-14-3) is subject to reporting under this section for the 
significant new uses described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1), (a)(2)(i), (a)(2)(iii), (a)(3), (a)(4) (National 
Institute for Occupational Safety and Health (NIOSH)-certified 
respirator with an assigned protection factor (APF) of at least 10), 
(a)(6)(i), (a)(6)(ii), (a)(6)(v), (a)(6)(vi), (b) (concentration set at 
1.0 percent), and (c).
    (ii) Release to water. Requirements as specified in Sec.  
721.90(a)(4), (b)(4), and (c)(4) (N=3).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (e) and (k) and are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
47. Add Sec.  [emsp14]721.10470 to subpart E to read as follows:

Sec.  [emsp14]721.10470  Phosphonium, tetrabutyl-, 1,1,2,2,3,3,4,4,4-
nonafluoro-1-butanesulfonate (1:1).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as phosphonium, 
tetrabutyl-, 1,1,2,2,3,3,4,4,4-nonafluoro-1-butanesulfonate (1:1) (PMN 
P-03-567; CAS No. 220689-12-3) is subject to reporting under this 
section for the significant new uses described in paragraph (a)(2) of 
this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(j).
    (ii) [Reserved].
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.

[[Page 58698]]

    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.
    (3) Determining whether a specific use is subject to this section. 
The provisions of Sec.  721.1725(b)(1) apply to paragraph (a)(2)(i) of 
this section.

0
48. Add Sec.  721.10471 to subpart E to read as follows:

Sec.  721.10471  2-Propenoic acid, 1,1'-(3-methyl-1,5-pentanediyl) 
ester.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as 2-propenoic acid, 
1,1'-(3-methyl-1,5-pentanediyl) ester (PMN P-03-622; CAS No. 64194-22-
5) is subject to reporting under this section for the significant new 
uses described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80 (f) and (j).
    (ii) [Reserved].
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.
    (3) Determining whether a specific use is subject to this section. 
The provisions of Sec.  721.1725(b)(1) apply to paragraph (a)(2)(i) of 
this section.

0
49. Add Sec.  721.10472 to subpart E to read as follows:

Sec.  721.10472  1,3-Benzenedimethanamine, polymers with 
epichlorohydrin-polyethylene glycol reaction products.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as 1,3-
benzenedimethanamine, polymers with epichlorohydrin-polyethylene glycol 
reaction products (PMN P-03-645; CAS No. 652968-34-8) is subject to 
reporting under this section for the significant new uses described in 
paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(f).
    (ii) [Reserved].
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
50. Add Sec.  721.10473 to subpart E to read as follows:

Sec.  721.10473  1-Propanaminium, 3-amino-N-(2-carboxyethyl)-N,N-
dimethyl-, N-coco acyl derivs., inner salts.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as 1-propanaminium, 3-
amino-N-(2-carboxyethyl)-N,N-dimethyl-, N-coco acyl derivs., inner 
salts (PMN P-03-865; CAS No. 499781-63-4) is subject to reporting under 
this section for the significant new uses described in paragraph (a)(2) 
of this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec.  
721.90(a)(4), (b)(4), and (c)(4) (N=85).
    (ii) [Reserved].
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
51. Add Sec.  721.10474 to subpart E to read as follows:

Sec.  721.10474  Substituted amino ethane sulfonic acid salt (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
substituted amino ethane sulfonic acid salt (PMN P-04-107) is subject 
to reporting under this section for the significant new uses described 
in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(j).
    (ii) [Reserved].
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.
    (3) Determining whether a specific use is subject to this section. 
The provisions of Sec.  721.1725(b)(1) apply to paragraph (a)(2)(i) of 
this section.

0
52. Add Sec.  721.10475 to subpart E to read as follows:

Sec.  721.10475  Hexanedioic acid, compd. with N1-(6-aminohexyl)-N1-
methyl-1,6-hexanediamine (1:1).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as hexanedioic acid, 
compd. with N1-(6-aminohexyl)-N1-methyl-1,6-hexanediamine (1:1) (PMN P-
04-118; CAS No. 659733-29-6) is subject to reporting under this section 
for the significant new uses described in paragraph (a)(2) of this 
section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(j) (intermediate for polymer manufacture).
    (ii) Release to water. Requirements as specified in Sec.  
721.90(a)(4), (b)(4), and (c)(4) (N=20).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), (i), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply this section.

0
53. Add Sec.  721.10476 to subpart E to read as follows:

Sec.  721.10476  Oxetane, 3-(bromomethyl)-3-methyl-.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as oxetane, 3-
(bromomethyl)-3-methyl- (PMN P-04-275; CAS No. 78385-26-9) is subject 
to reporting under this section for the significant new uses described 
in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1), (a)(3), (b) (concentration set at 1.0 percent), and (c).

[[Page 58699]]

    (ii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(g).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (e) and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
54. Add Sec.  721.10477 to subpart E to read as follows:

Sec.  721.10477  Acrylate ester (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
acrylate ester (PMN P-04-290) is subject to reporting under this 
section for the significant new uses described in paragraph (a)(2) of 
this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(j).
    (ii) [Reserved].
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.
    (3) Determining whether a specific use is subject to this section. 
The provisions of Sec.  721.1725(b)(1) apply to paragraph (a)(2)(i) of 
this section.

0
55. Add Sec.  721.10478 to subpart E to read as follows:

Sec.  721.10478  Polyether polyol (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
polyether polyol (PMN P-04-318) is subject to reporting under this 
section for the significant new uses described in paragraph (a)(2) of 
this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(j) (intermediate for making urethane 
polymer).
    (ii) Release to water. Requirements as specified in Sec.  
721.90(a)(4), (b)(4), and (c)(4) (N=30).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), (i), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
56. Add Sec.  721.10479 to subpart E to read as follows:

Sec.  721.10479  Quaternary ammonium compounds, tris(hydrogenated 
tallow alkyl)methyl, chlorides.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as quaternary ammonium 
compounds, tris(hydrogenated tallow alkyl)methyl, chlorides (PMN P-04-
335; CAS No. 308074-73-9) is subject to reporting under this section 
for the significant new uses described in paragraph (a)(2) of this 
section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(j).
    (ii) [Reserved].
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.
    (3) Determining whether a specific use is subject to this section. 
The provisions of Sec.  721.1725(b)(1) apply to paragraph (a)(2)(i) of 
this section.

0
57. Add Sec.  721.10480 to subpart E to read as follows:

Sec.  721.10480  Trimethylolpropane polyol, aminated (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
trimethylolpropane polyol, aminated (PMN P-04-384) is subject to 
reporting under this section for the significant new uses described in 
paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec.  
721.90(a)(4), (b)(4), and (c)(4) (N=9).
    (ii) [Reserved].
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
58. Add Sec.  721.10481 to subpart E to read as follows:

Sec.  721.10481  Siloxanes and Silicones, Me vinyl, hydroxy-terminated, 
reaction products with silica.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as Siloxanes and 
Silicones, Me vinyl, hydroxy-terminated, reaction products with silica 
(PMN P-04-429; CAS No. 630106-01-3) is subject to reporting under this 
section for the significant new uses described in paragraph (a)(2) of 
this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(v)(1), (w)(1), and (x)(1).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
59. Add Sec.  721.10482 to subpart E to read as follows:

Sec.  721.10482  Siloxanes and Silicones, di-Me, Me vinyl, hydroxy-
terminated, reaction products with silica.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as Siloxanes and 
Silicones, di-Me, Me vinyl, hydroxy-terminated, reaction products with 
silica (PMN P-04-430; CAS No. 630106-00-2) is subject to reporting 
under this section for the significant new uses described in paragraph 
(a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80 (v)(1), (w)(1), and (x)(1).

[[Page 58700]]

    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
60. Add Sec.  721.10483 to subpart E to read as follows:

Sec.  721.10483  Siloxanes and Silicones, di-Me, Me vinyl, hydroxy-
terminated, reaction products with [(ethenyldimethylsilyl)oxy]-modified 
silica.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as Siloxanes and 
Silicones, di-Me, Me vinyl, hydroxy-terminated, reaction products with 
[(ethenyldimethylsilyl)oxy]-modified silica (PMN P-04-431; CAS No. 
630106-04-6) is subject to reporting under this section for the 
significant new uses described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80 (v)(1), (w)(1), and (x)(1).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
61. Add Sec.  721.10484 to subpart E to read as follows:

Sec.  721.10484  Siloxanes and Silicones, Me vinyl, hydroxy-terminated, 
reaction products with [(ethenyldimethylsilyl)oxy]-modified silica.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as Siloxanes and 
Silicones, Me vinyl, hydroxy-terminated, reaction products with 
[(ethenyldimethylsilyl)oxy]-modified silica (PMN P-04-432; CAS No. 
630106-02-4) is subject to reporting under this section for the 
significant new uses described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80 (v)(1), (w)(1), and (x)(1).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
62. Add Sec.  721.10485 to subpart E to read as follows:

Sec.  721.10485  Reaction products of alcohols, alkyl alcohols, amino 
alcohols and methanol sodium salts (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
reaction products of alcohols, alkyl alcohols, amino alcohols and 
methanol sodium salts (PMN P-04-479) is subject to reporting under this 
section for the significant new uses described in paragraph (a)(2) of 
this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(j).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.
    (3) Determining whether a specific use is subject to this section. 
The provisions of Sec.  721.1725(b)(1) apply to paragraph (a)(2)(i) of 
this section.

0
63. Add Sec.  721.10486 to subpart E to read as follows:

Sec.  721.10486  Alkyl substituted amino-benzamide (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as alkyl 
substituted amino-benzamide (PMN P-04-591) is subject to reporting 
under this section for the significant new uses described in paragraph 
(a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(j) (acetaldehyde scavenger for plastic 
bottle production).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
64. Add Sec.  721.10487 to subpart E to read as follows:

Sec.  721.10487  Alkylbenzenes sulfonic acids, metal salts (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substances identified generically as 
alkylbenzenes sulfonic acids, metal salts (PMNs P-04-599, P-04-600, P-
04-605, and P-04-606) are subject to reporting under this section for 
the significant new uses described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(j).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of these substances.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.
    (3) Determining whether a specific use is subject to this section. 
The provisions of Sec.  721.1725(b)(1) apply to paragraph (a)(2)(i) of 
this section.

0
65. Add Sec.  721.10488 to subpart E to read as follows:

Sec.  721.10488  Cuprate, [[[[[[[(sulfonaphthalenyl)]azo]-
(substitutedphenyl)]azo]-(substitutedsulfonaphthalenyl)]azo]-
substituted phenyl-substituted heteromonocycle], sodium salts 
(generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
cuprate, [[[[[[[(sulfonaphthalenyl)]azo]-

[[Page 58701]]

(substitutedphenyl)]azo]-(substitutedsulfonaphthalenyl)]azo]-
substituted phenyl-substituted heteromonocycle], sodium salts (PMN P-
04-636) is subject to reporting under this section for the significant 
new uses described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1), (a)(4) (National Institute for Occupational Safety and 
Health (NIOSH)-certified respirator with an assigned protection factor 
(APF) of at least 5), (a)(6)(i), (a)(6)(ii), (a)(6)(v), (a)(6)(vi), (b) 
(concentration set at 0.1 percent), and (c).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (e) are applicable to manufacturers, importers, and 
processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
66. Add Sec.  721.10489 to subpart E to read as follows:

Sec.  721.10489  Substituted aryl sulfonium polyfluorophosphate salts 
(generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
substituted aryl sulfonium polyfluorophosphate salts (PMN P-04-718) is 
subject to reporting under this section for the significant new uses 
described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80 (v)(1), (v)(2), (w)(1), (w)(2), (x)(1), 
and (x)(2).
    (ii) Release to water. Requirements as specified in Sec.  
721.90(a)(4), (b)(4), and (c)(4) (N = 6).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), (i), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
67. Add Sec.  721.10490 to subpart E to read as follows:

Sec.  721.10490  HDI biuret, hydroxyethyl methacrylate prepolymer 
(generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as HDI 
biuret, hydroxyethyl methacrylate prepolymer (PMN P-04-834) is subject 
to reporting under this section for the significant new uses described 
in paragraph (a)(2) of this section. The requirements of this section 
do not apply to quantities of the PMN substance that have been 
completely reacted (cured).
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1), (a)(2), (a)(3), (a)(4), (b) (concentration set at 0.1 
percent), and (c). The following National Institute for Occupational 
Safety and Health (NIOSH)-certified respirators with an assigned 
protection factor (APF) of at least 25 meet the minimum requirements 
for Sec.  721.63(a)(4): NIOSH-certified air-purifying, tight-fitting 
half-face respirator equipped with N100 (if oil aerosols absent), R100, 
or P100 filters; NIOSH-certified air-purifying, tight-fitting full-face 
respirator equipped with N100 (if oil aerosols absent), R100, or P100 
filters; NIOSH-certified powered air-purifying respirator equipped with 
a loose-fitting hood or helmet and high efficiency particulate air 
(HEPA) filters; NIOSH-certified powered air-purifying respirator 
equipped with a tight-fitting facepiece (either half-face or full-face) 
and HEPA filters; or NIOSH-certified supplied-air respirator operated 
in pressure demand or continuous flow mode and equipped with a hood or 
helmet, or tight-fitting facepiece (either half-face or full-face).
    (A) As an alternative to the respiratory requirements listed in 
paragraph (a)(2)(i), a manufacturer, importer, or processor may choose 
to follow the new chemical exposure limit (NCEL) provisions listed in 
the TSCA section 5(e) consent order for this substance. The NCEL is 
0.05 mg/m\3\ as an 8-hour time-weighted average. Persons who wish to 
pursue NCELs as an alternative to Sec.  721.63 respirator requirements 
may request to do so under Sec.  721.30. Persons whose Sec.  721.30 
requests to use the NCELs approach are approved by EPA will be required 
to follow NCELs provisions comparable to those contained in the 
corresponding TSCA section 5(e) consent order.
    (B) [Reserved]
    (ii) Hazard communication program. Requirements as specified in 
Sec.  721.72(a), (b), (c), (d), (e) (concentration set at 0.1 percent), 
(f), (g)(1)(i), (g)(1)(ii), (g)(1)(vii), (g)(2)(i), (g)(2)(ii), 
(g)(2)(iii), (g)(2)(iv), (g)(2)(v), and (g)(5).
    (iii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(q).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (i) are applicable to manufacturers, importers, and 
processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.
    (3) Determining whether a specific use is subject to this section. 
The provisions of Sec.  721.1725(b)(1) apply to paragraph (a)(2)(iii) 
of this section.

0
68. Add Sec.  721.10491 to subpart E to read as follows:

Sec.  721.10491  Benzenepropanal,.alpha.-methyl-.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as 
benzenepropanal,.alpha.-methyl- (PMN P-05-55; CAS No. 5445-77-2) is 
subject to reporting under this section for the significant new uses 
described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(h).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
69. Add Sec.  721.10492 to subpart E to read as follows:

Sec.  721.10492  Trisphenol (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
trisphenol (PMN P-05-301) is subject to reporting under this section 
for the significant new uses described in paragraph (a)(2) of this 
section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec.  
721.90(a)(4), (b)(4), and (c)(4) (N = 20).

[[Page 58702]]

    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
70. Add Sec.  721.10493 to subpart E to read as follows:

Sec.  721.10493  Tris-alkyl-alkoxy melamine polymer (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as tris-
alkyl-alkoxy melamine polymer (PMN P-05-417) is subject to reporting 
under this section for the significant new uses described in paragraph 
(a)(2) of this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec.  
721.90(a)(4), (b)(4), and (c)(4) (N = 5).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
71. Add Sec.  721.10494 to subpart E to read as follows:

Sec.  721.10494  Reaction product of trimethylolpropane triacrylate and 
alkylene imine (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
reaction product of trimethylolpropane triacrylate and alkylene imine 
(PMN P-05-501) is subject to reporting under this section for the 
significant new uses described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec.  
721.90(a)(4), (b)(4), and (c)(4) (N = 5).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
72. Add Sec.  721.10495 to subpart E to read as follows:

Sec.  721.10495  Metal silicate (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as metal 
silicate (PMN P-05-634) is subject to reporting under this section for 
the significant new uses described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80 (f) and (j).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.
    (3) Determining whether a specific use is subject to this section. 
The provisions of Sec.  721.1725(b)(1) apply to paragraph (a)(2)(i) of 
this section.

0
73. Add Sec.  721.10496 to subpart E to read as follows:

Sec.  [emsp14]721.10496  Amino alkoxy polydimethylsiloxane, hydroxy-
terminated (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as amino 
alkoxy polydimethylsiloxane, hydroxy-terminated (PMN P-06-9) is subject 
to reporting under this section for the significant new uses described 
in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec.  
721.90(a)(4), (b)(4), and (c)(4) (N = 10).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
74. Add Sec.  721.10497 to subpart E to read as follows:

Sec.  721.10497  Substituted alkyl ester, hydrolysis products with 
silica and substituted silane (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substances identified generically as 
substituted alkyl ester, hydrolysis products with silica and 
substituted silane (PMNs P-06-276 and P-06-279) are subject to 
reporting under this section for the significant new uses described in 
paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1), (a)(2)(i), (a)(2)(iv), (a)(3), (a)(4), (b) (concentration 
set 1.0 percent), and (c). The following National Institute for 
Occupational Safety and Health (NIOSH)-certified respirators with an 
assigned protection factor (APF) of at least 5 meet the requirements of 
Sec.  721.63(a)(4): NIOSH-certified air-purifying, tight-fitting full-
face respirator equipped with N100 (if oil aerosols absent), R100, or 
P100 filters; NIOSH-certified air-purifying respirator equipped with a 
loose-fitting hood or helmet and high efficiency particulate air (HEPA) 
filters; NIOSH-certified powered air-purifying respirator equipped with 
a tightfitting facepiece (full-face) and HEPA filters; or NIOSH-
certified supplied-air respirator operated in pressure demand or 
continuous flow mode and equipped with a hood or helmet, or tight-
fitting facepiece (full-face).
    (ii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80 (j), (v)(1), (w)(1), and (x)(1).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (e) and (i) are applicable to manufacturers, 
importers, and processors of these substances.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.
    (3) Determining whether a specific use is subject to this section. 
The provisions

[[Page 58703]]

of Sec.  721.1725(b)(1) apply to paragraph (a)(2)(ii) of this section.

0
75. Add Sec.  721.10498 to subpart E to read as follows:

Sec.  721.10498  Substituted alkyl ester, hydrolysis products with 
silica (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substances identified generically as 
substituted alkyl ester, hydrolysis products with silica (PMNs P-06-277 
and P-06-280) are subject to reporting under this section for the 
significant new uses described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1), (a)(2)(i), (a)(2)(iv), (a)(3), (a)(4), (b) (concentration 
set at 1.0 percent), and (c). The following National Institute for 
Occupational Safety and Health (NIOSH)-certified respirators with an 
assigned protection factor (APF) of at least 5 meet the requirements of 
Sec.  721.63(a)(4): NIOSH-certified air-purifying, tight-fitting full-
face respirator equipped with N100 (if oil aerosols absent), R100, or 
P100 filters; NIOSH-certified air-purifying respirator equipped with a 
loose-fitting hood or helmet and high efficiency particulate air (HEPA) 
filters; NIOSH-certified powered air-purifying respirator equipped with 
a tightfitting facepiece (full-face) and HEPA filters; or NIOSH-
certified supplied-air respirator operated in pressure demand or 
continuous flow mode and equipped with a hood or helmet, or tight-
fitting facepiece (full-face).
    (ii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80 (j), (v)(1), (w)(1), and (x)(1).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (e) and (i) are applicable to manufacturers, 
importers, and processors of these substances.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.
    (3) Determining whether a specific use is subject to this section. 
The provisions of Sec.  721.1725(b)(1) apply to paragraph (a)(2)(ii) of 
this section.

0
76. Add Sec.  721.10499 to subpart E to read as follows:

Sec.  721.10499  Substituted silane, hydrolysis products with silica 
(generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substances identified generically as 
substituted silane, hydrolysis products with silica (PMNs P-06-278 and 
P-06-281) are subject to reporting under this section for the 
significant new uses described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1), (a)(2)(i), (a)(2)(iv), (a)(3), (a)(4), (b) (concentration 
set at 1.0 percent), and (c). The following National Institute for 
Occupational Safety and Health NIOSH-certified respirators with an 
assigned protection factor (APF) of at least 5 meet the requirements of 
Sec.  721.63(a)(4): NIOSH-certified air-purifying, tight-fitting full-
face respirator equipped with N100 (if oil aerosols absent), R100, or 
P100 filters; NIOSH-certified air-purifying respirator equipped with a 
loose-fitting hood or helmet and high efficiency particulate air (HEPA) 
filters; NIOSH-certified powered air-purifying respirator equipped with 
a tight-fitting facepiece (full-face) and HEPA filters; or NIOSH-
certified supplied-air respirator operated in pressure demand or 
continuous flow mode and equipped with a hood or helmet, or tight-
fitting facepiece (full-face).
    (ii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80 (j), (v)(1), (w)(1), and (x)(1).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (e) and (i) are applicable to manufacturers, 
importers, and processors of these substances.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.
    (3) Determining whether a specific use is subject to this section. 
The provisions of Sec.  721.1725(b)(1) apply to paragraph (a)(2)(ii) of 
this section.

0
77. Add Sec.  721.10500 to subpart E to read as follows:

Sec.  721.10500  Acrylated mixed metal oxides (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
acrylated mixed metal oxides (PMN P-06-341) is subject to reporting 
under this section for the significant new uses described in paragraph 
(a)(2) of this section.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1), (a)(2)(i), (a)(3), (b) (concentration set at 1.0 
percent), and (c).
    (ii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80 (j), (v)(1), (w)(1), and (x)(1).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (e) and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.
    (3) Determining whether a specific use is subject to this section. 
The provisions of Sec.  721.1725(b)(1) apply to paragraph (a)(2)(ii) of 
this section.

0
78. Add Sec.  721.10501 to subpart E to read as follows:

Sec.  721.10501  Tridecyl phthalate (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
tridecyl phthalate (PMN P-06-542) is subject to reporting under this 
section for the significant new uses described in paragraph (a)(2) of 
this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(j).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.
    (3) Determining whether a specific use is subject to this section. 
The provisions of Sec.  721.1725(b)(1) apply to paragraph (a)(2)(i) of 
this section.

0
79. Add Sec.  721.10502 to subpart E to read as follows:

Sec.  721.10502  Modified triethylene glycol dithiol (generic).

    (a) Chemical substance and significant new uses subject to 
reporting.

[[Page 58704]]

(1) The chemical substance identified generically as modified 
triethylene glycol dithiol (PMN P-06-616) is subject to reporting under 
this section for the significant new uses described in paragraph (a)(2) 
of this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec.  
721.90(a)(4), (b)(4), and (c)(4) (N=2).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
80. Add Sec.  721.10503 to subpart E to read as follows:

Sec.  721.10503  1,2-Ethanediol, 1-carbamate.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as 1,2-ethanediol, 1-
carbamate (PMN P-06-622; CAS No. 5395-01-7) is subject to reporting 
under this section for the significant new uses described in paragraph 
(a)(2) of this section.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(2)(i), (a)(3), (b) (concentration set at 0.1 percent), and 
(c).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (e) are applicable to manufacturers, importers, and 
processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
81. Add Sec.  721.10504 to subpart E to read as follows:

Sec.  721.10504  Surface modified magnesium hydroxide (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as surface 
modified magnesium hydroxide (PMN P-06-682) is subject to reporting 
under this section for the significant new uses described in paragraph 
(a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80 (j) (compatibilizer for flame retardant 
for plastics) and (s) (100,000 kilograms).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
82. Add Sec.  721.10505 to subpart E to read as follows:

Sec.  [emsp14]721.10505  Phosphoric acid, mixed mono- and diesters with 
2-ethyl-1-hexanol and polyethylene glycol mono-C12-16-alkyl 
ethers.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as phosphoric acid, 
mixed mono- and diesters with 2-ethyl-1-hexanol and polyethylene glycol 
mono-C12-16-alkyl ethers (PMN P-06-694; CAS No. 882693-50-7) 
is subject to reporting under this section for the significant new uses 
described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80 (j) and (s) (75,000 kilograms).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.
    (3) Determining whether a specific use is subject to this section. 
The provisions of Sec.  721.1725(b)(1) apply to paragraph (a)(2)(i) of 
this section.

0
83. Add Sec.  721.10506 to subpart E to read as follows:

Sec.  721.10506  Alkylated phenols (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substances identified generically as 
alkylated phenols (PMNs P-07-11 and P-08-29) are subject to reporting 
under this section for the significant new uses described in paragraph 
(a)(2) of this section.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1), (a)(2)(i), (a)(3), (b) (concentration set at 1.0 
percent), and (c).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (e) are applicable to manufacturers, importers, and 
processors of these substances.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
84. Add Sec.  721.10507 to subpart E to read as follows:

Sec.  721.10507  Biphenyl substituted benzopyran (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
biphenyl substituted benzopyran (PMN P-07-107) is subject to reporting 
under this section for the significant new uses described in paragraph 
(a)(2) of this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec.  
721.90(a)(4), (b)(4), and (c)(4) (N=2).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
85. Add Sec.  721.10508 to subpart E to read as follows:

Sec.  721.10508  Alkene substituted Bis phenol (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as alkene 
substituted bis phenol (PMN P-07-161) is subject to reporting under 
this section for the significant new uses described in paragraph (a)(2) 
of this section.
    (2) The significant new uses are:

[[Page 58705]]

    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1), (a)(3), (b) (concentration set at 0.1 percent), and (c).
    (ii) Release to water. Requirements as specified in Sec.  721.90 
(a)(1), (b)(1), and (c)(1).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (e) and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
86. Add Sec.  721.10509 to subpart E to read as follows:

Sec.  721.10509  Pentane, 1,1,1,2,3,3-hexafluoro-4-(1,1,2,3,3,3-
hexafluoropropoxy)-.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as pentane, 
1,1,1,2,3,3-hexafluoro-4-(1,1,2,3,3,3-hexafluoropropoxy)- (PMN P-07-
204; CAS No. 870778-34-0) is subject to reporting under this section 
for the significant new uses described in paragraph (a)(2) of this 
section.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1), (a)(2)(i), (a)(3), (b) (concentration set at 1.0 
percent), and (c).
    (ii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(j).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (e) and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.
    (3) Determining whether a specific use is subject to this section. 
The provisions of Sec.  721.1725(b)(1) apply to paragraph (a)(2)(ii) of 
this section.

0
87. Add Sec.  721.10510 to subpart E to read as follows:

Sec.  721.10510  Alkylaminoalcohol (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
alkylaminoalcohol (PMN P-07-319) is subject to reporting under this 
section for the significant new uses described in paragraph (a)(2) of 
this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec.  
721.90(a)(4), (b)(4), and (c)(4) (N=1).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
88. Add Sec.  721.10511 to subpart E to read as follows:

Sec.  721.10511  Quaternary ammonium salts (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substances identified generically as 
quaternary ammonium salts (PMNs P-07-320, P-07-321, P-07-322, P-07-323, 
and P-07-324) are subject to reporting under this section for the 
significant new uses described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(j).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of these substances.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.
    (3) Determining whether a specific use is subject to this section. 
The provisions of Sec.  721.1725(b)(1) apply to paragraph (a)(2)(i) of 
this section.

0
89. Add Sec.  [emsp14]721.10512 to subpart E to read as follows:

Sec.  [emsp14]721.10512  Fatty acid maleic acid amides (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substances identified generically as fatty 
acid maleic acid amides (PMNs P-07-563 and P-07-564) are subject to 
reporting under this section for the significant new uses described in 
paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec.  
721.90(a)(4), (b)(4), and (c)(4) (N=10).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of these substances.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
90. Add Sec.  [emsp14]721.10513 to subpart E to read as follows:

Sec.  [emsp14]721.10513  Aromatic acrylate monomer (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
aromatic acrylate monomer (PMN P-07-599) is subject to reporting under 
this section for the significant new uses described in paragraph (a)(2) 
of this section.
    (2) The significant new uses are:
    (i) Release to water. Requirements as specified in Sec.  
721.90(a)(4), (b)(4), and (c)(4) (N=1).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
91. Add Sec.  [emsp14]721.10514 to subpart E to read as follows:

Sec.  [emsp14]721.10514  [1,1'-Biphenyl]-2,2'-disulfonic acid, 4-[2-
(4,5-dihydro-3-methyl-5-oxo-1-phenyl-1H-pyrazol-4-yl)diazenyl]-4'-[2-
(2-hydroxy-1-naphthalenyl)diazenyl]-, sodium salt (1:2).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as [1,1'-Biphenyl]-
2,2'-disulfonic acid, 4-[2-(4,5-dihydro-3-methyl-5-oxo-1-phenyl-1H-
pyrazol-4-yl)diazenyl]-4'-[2-(2-hydroxy-1-naphthalenyl)diazenyl]-, 
sodium salt (1:2) (PMN P-07-679; CAS No. 6470-20-8) is subject to 
reporting

[[Page 58706]]

under this section for the significant new uses described in paragraph 
(a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80 (f), (v)(2), and (x)(2).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.

0
92. Add Sec.  [emsp14]721.10515 to subpart E to read as follows:

Sec.  [emsp14]721.10515  Partially fluorinated alcohol substituted 
glycols (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substances identified generically as 
partially fluorinated alcohol substituted glycols (PMNs P-10-58, P-10-
59, and P-10-60) are subject to reporting under this section for the 
significant new uses described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80 (k) (manufacture and import of the PMN 
substances according to the chemical synthesis and composition section 
of the consent order, including analysis, reporting, and limitations of 
maximum impurity levels of certain fluorinated impurities; manufacture 
and import of P-10-58 and P-10-59 only as described in the 
manufacturing section of the consent order), (l) (compliance with the 
maximum established percentage of the PMN substances in a non-
industrial product or distributed for use as a non-industrial product), 
(o) (use of P-10-60 in a consumer product that could be spray applied), 
and (q).
    (ii) [Reserved]
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph.
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a), (b), (c), and (i) are applicable to manufacturers, 
importers, and processors of these substances, except the recordkeeping 
requirements for Sec.  721.125 (b) and (c) do not apply to importers or 
processors when any one of the substances are contained in a 
formulation at less than 3 weight percent.
    (2) Limitations or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.
    (3) Determining whether a specific use is subject to this section. 
The provisions of Sec.  721.1725(b)(1) apply to paragraph (a)(2)(i) of 
this section.

[FR Doc. 2012-23235 Filed 9-20-12; 8:45 am]
BILLING CODE 6560-50-P