Document ID: EPA-HQ-OPP-2008-0624-0008
Agency: epa
Document Type: Supporting & Related Material
Title: 
Posted Date: 2009-09-16T04:00Z

UNITED STATES ENVIRONMENTAL PROTECTION AGENCY

WASHINGTON, D.C. 20460      

	OFFICE OF PREVENTION, PESTICIDE

	AND TOXIC SUBSTANCES

	

  SEQ CHAPTER \h \r 1 MEMORANDUM

Date:  11/24/2008

SUBJECT:  Boscalid.  Chronic Dietary (Food and Drinking Water) Exposure
Analysis for the Imported Banana Tolerance Increase Resulting from the
Use of New Formulation  

 

PC Code:  128008	DP Number:  357496  

Decision No.:  394534	Registration No.:  None 

Petition Nos.:  8E7366	Regulatory Action:  Section 3 

Risk Assessment Type:  None 	Case No.:  None 

TXR No.:  None	CAS No.:  188425-85-6

MRID No.:   None	40 CFR:  180.589

		              							

	          	

FROM:  	Douglas Dotson, Ph.D., Chemist

	Registration Action Branch 2

	Health Effects Division (7509P)  SEQ CHAPTER \h \r 1 		

		

THROUGH:	Thurston Morton, Chemist

		P. Yvonne Barnes, Chemist

		Christina Swartz, Branch Chief

	Registration Action Branch 2

Health Effects Division (7509P)  SEQ CHAPTER \h \r 1 	

		

TO:		Bryant Crowe/Tony Kish, RM Team 22

		Fungicide Branch

		Registration Division (7505P)

Executive Summary

A chronic aggregate dietary (food and drinking water) exposure and risk
assessment was conducted using the Dietary Exposure Evaluation Model
DEEM-FCID™, Version 2.03 which uses food consumption data from the
U.S. Department of Agriculture’s Continuing Surveys of Food Intakes by
Individuals (CSFII) from 1994-1996 and 1998.  The analysis was performed
to support a tolerance increase for bananas.  In addition, HED
anticipates that a recommendation will be made for the establishment of
a tolerance for coffee in the near future.  For this reason, coffee is
being included in the current assessment as well.

   

Acute Dietary Exposure Results and Characterization

No toxic effects attributable to a single (i.e., acute) exposure to
boscalid have been identified.  As a result, an acute reference dose
(RfD) was not established for this chemical and an acute dietary
exposure assessment was not conducted.

Chronic Dietary (Food and Drinking Water) Exposure Results and
Characterization

A chronic dietary (food and drinking water) exposure and risk assessment
was conducted for boscalid using tolerance level residues and 100% crop
treated assumptions.  Boscalid exposure from the existing uses, the
proposed use on coffee, and the proposed tolerance increase for bananas
results in an estimated risk estimate equivalent to 10% of the chronic
population adjusted dose (cPAD) for the U.S. population.  The most
highly exposed population subgroup is Children 1–2 years of age, which
utilizes 33% of the cPAD.  

Cancer Dietary Exposure Results and Characterization

Boscalid was classified as demonstrating “suggestive evidence of
carcinogenicity” by the Cancer Assessment Review Committee (CARC). 
This committee recommended against quantification of human cancer risk,
however.  No change has been made to the cancer classification.  As a
result, a dietary cancer assessment is not required.

I.	Introduction

Dietary risk assessment incorporates both exposure and toxicity of a
given pesticide.  For acute and chronic assessments, the risk is
expressed as a percentage of a maximum acceptable dose (i.e., the dose
which HED has concluded will result in no unreasonable adverse health
effects).  This dose is referred to as the population adjusted dose
(PAD).  The PAD is equivalent to the point of departure (PoD, NOAEL,
LOAEL, e.g.) divided by the required uncertainty or safety factors.

For acute and non-cancer chronic exposures, HED is concerned when
estimated dietary risk exceeds 100% of the PAD.  HED is generally
concerned when estimated cancer risk exceeds one in one million. 
References that discuss the acute and chronic risk assessments in more
detail are available on the EPA/pesticides web site:  “Available
Information on Assessing Exposure from Pesticides, A User’s Guide,”
21-JUN-2000, web link:      HYPERLINK
"http://www.epa.gov/fedrgstr/EPA-PEST/2000/July/Day-12/6061.pdf" 
http://www.epa.gov/fedrgstr/EPA-PEST/2000/July/Day-12/6061.pdf  ; or see
SOP 99.6 (20-AUG-1999).

The most recent dietary risk assessment for boscalid was conducted by D.
Davis (Memo, D336633, 12/17/2007).

II.	Residue Information

Food Residues

Boscalid per se is the residue of concern for both the tolerance
expression and risk assessment in target and rotational crops.  In
livestock, the residues of concern for both the tolerance expression and
risk assessment are the combined residues of boscalid and the free and
conjugated hydroxy metabolites.  Boscalid per se is the residue of
concern in drinking water.

Tolerances for residues of boscalid are established under 40CFR
§180.589.  Primary crop tolerances range from 0.05 ppm in/on peanuts
and tuberous and corm vegetables to 60 ppm in leafy greens (Crop
Subgroup 4-A, except head and leaf lettuce).  Livestock tolerances range
from 0.02 ppm in/on egg to 0.35 ppm in the meat byproducts of cattle,
goats, horses, and sheep.  Indirect or inadvertent tolerances range from
0.05 ppm to 8 ppm.  Finally, time-limited tolerances are established for
tangerines and Belgian endive.

The revised and proposed tolerances that are being included in this
assessment are as follows:

			Bananas:   0.04 ppm (previously 0.02 ppm)

			Coffee:     0.05 ppm

The chronic dietary exposure analysis is based on tolerance level
residues for all commodities.  

For processed commodities for which data were available to show no
concentration of residues (apple juice, prunes, rice bran, wheat flour,
sunflower oil, mint oil, tomato puree, tomato juice, soybean oil and
cottonseed oil), the processing factor was set to 1.  For processed
commodities where the RAC tolerance is adequate to cover the very slight
concentration seen in the processing study (wheat germ, wheat bran,  and
tomato paste), the residue was set at the RAC level and the processing
factor was reduced to 1.   For processed commodities with established
tolerances (raisin, peanut oil), the processed commodity tolerance was
used and the processing factor was set to 1.0.  For all other processed
commodities for which data were not available, DEEM (Version 7.81)
processing factors were used.  A review of the processing studies for
the registered commodities (except apples and soybeans) can be found in
the residue chemistry summary document that included the first
established tolerances for boscalid (Memo, D278385, M. Nelson,
08/15/2003).  A review of the processing studies for apples and soybeans
can be found in the residue chemistry summary document that included
those commodities (Memo, D290185, D. Dotson, 02/10/2004).  The
processing data for the use on cottonseed oil can be found in the
residue chemistry summary document Memo, D336632, C. Olinger, 11/27/07.

Drinking Water Residues

The estimated drinking water concentrations (EDWCs) used in the dietary
risk assessment were provided by the Environmental Fate and Effects
Division (EFED) in the following memorandum: “Drinking Water
Assessment for the IR-4 Petition for the Use of Boscalid on Tropical
Fruits and Fresh Herbs, and a Proposed New Use on Cotton” (D336183, C.
Sutton, 8/8/2007).  EFED prepared this memo for the previous boscalid
risk assessment.  The water numbers were based on the turf use.  The
current requests for an increase in the banana tolerance and the use on
coffee do not affect the EDWCs.  Both requests are for import
tolerances.  As a result, the EDWCs used in the previous assessment were
used in this assessment as well.  The EDWCs were incorporated directly
into this dietary assessment into the food categories “water, direct,
all sources” and “water, indirect, all sources.”   

The EDWCs for boscalid in surface water and groundwater were calculated
using the screening model FIRST (FQPA Index Reservoir Screening Tool;
v.1.10; dated 12/12/2005) and the regression model SCI-GROW (Screening
Concentration in Ground Water, v.2.3; dated 7/29/2003), respectively. 
The maximum Tier 1 estimated chronic groundwater EDWC is 0.63 ppb.  The
maximum Tier 1 estimated chronic surface water EDWC is 29.6 ppb.  The
surface water value is higher than the groundwater value and was
therefore used in the assessment.  The EFED models and their
descriptions are available at the EPA internet site:   HYPERLINK
"http://www.epa.gov/oppefed1/models/water/" 
http://www.epa.gov/oppefed1/models/water/ .

The residue values (food and drinking water) and processing factors used
in the chronic dietary exposure assessment are included in Attachment 1,
Chronic Residue Input File.

III.	Percent Crop Treated Information

The assumption was made that all crops in the assessment would be
treated to a level of 100%.

EEM-FCID™ Program and Consumption Information

The boscalid chronic dietary exposure assessment was conducted using the
Dietary Exposure Evaluation Model software with the Food Commodity
Intake Database DEEM-FCID™, Version 2.03 which incorporates
consumption data from USDA’s Continuing Surveys of Food Intakes by
Individuals (CSFII), 1994-1996 and 1998.  The 1994-96, 98 data are based
on the reported consumption of more than 20,000 individuals over two
non-consecutive survey days.  Foods “as consumed” (e.g., apple pie)
are linked to EPA-defined food commodities (e.g. apples, peeled fruit -
cooked; fresh or N/S; baked; or wheat flour - cooked; fresh or N/S,
baked) using publicly available recipe translation files developed
jointly by USDA/ARS and EPA.  For chronic exposure assessment,
consumption data are averaged for the entire U.S. population and within
population subgroups, but for acute exposure assessment are retained as
individual consumption events.  Based on analysis of the 1994-96, 98
CSFII consumption data, which took into account dietary patterns and
survey respondents, HED concluded that it is most appropriate to report
risk for the following population subgroups: the general U.S.
population, all infants (<1 year old), children 1-2, children 3-5,
children 6-12, youth 13-19, adults 20-49, females 13-49, and adults 50+
years old.

For chronic dietary exposure assessment, an estimate of the residue
level in each food or food-form (e.g., orange or orange juice) on the
food commodity residue list is multiplied by the average daily
consumption estimate for that food/food form to produce a residue intake
estimate.  The resulting residue intake estimate for each food/food form
is summed with the residue intake estimates for all other food/food
forms on the commodity residue list to arrive at the total average
estimated exposure.  Exposure is expressed in mg/kg body weight/day and
as a percent of the cPAD.  This procedure is performed for each
population subgroup.

V.	Toxicological Information

HED’s Hazard Identification Assessment Review Committee (HIARC) met on
September 5, 2002 and January 23, 2003 to evaluate the toxicology
database for boscalid (Report dated 3/7/03, TXR No. 0051613).  No new
studies have been received and no changes are being made to the
endpoints that were selected at that time.  The standard uncertainty
factor of 100 to account for inter- and intra-species variability was
applied to all risk assessments.  The FQPA safety factor for boscalid
was reduced to 1x because the toxicity database is complete, there is no
concern for neurotoxicity, there is no evidence of increased pre- or
post-natal susceptibility, and exposure estimates are not expected to
underestimate risk.  The boscalid dietary endpoints are summarized in
Table 1, below.



Table 1.  Summary of Toxicological Doses and Endpoints for Boscalid for
Use in Dietary Risk Assessments

Exposure/

Scenario	Point of Departure	Uncertainty/FQPA Safety Factors	RfD/PAD
Study and Toxicological Effects

Acute Dietary

(All Populations)	

No appropriate endpoint attributable to a single dose was available in
the current database, including the developmental toxicity studies. 
Therefore, an acute RfD was not established for the general U.S.
population or any population subgroup.

Chronic Dietary

(All Populations)	NOAEL = 21.8 mg/kg/day

	UFA = 10x

UFH = 10x

FQPA SF = 1x

	Chronic RfD =  0.218 mg/kg/day

Chronic PAD = 0.218 mg/kg/day	Chronic rat, carcinogenicity rat and
1-year dog studies

LOAEL = ~58 mg/kg/day based on liver and thyroid effects

Cancer

	

Classified as “suggestive evidence of carcinogenicity.” 
Quantification of human cancer risk is not recommended.

Point of Departure (PoD) = A data point or an estimated point that is
derived from observed dose-response data and used to mark the beginning
of extrapolation to determine risk associated with lower environmentally
relevant human exposures.  NOAEL = no observed adverse effect level. 
LOAEL = lowest observed adverse effect level.  UF = uncertainty factor. 
UFA = extrapolation from animal to human (intraspecies).  UFH =
potential variation in sensitivity among members of the human population
(interspecies).  FQPA SF = FQPA Safety Factor.  PAD = population
adjusted dose.  RfD = reference dose.  

VI.	Results/Discussion 

As stated above, for chronic assessments, HED is concerned when dietary
risk exceeds 100% of the cPAD.  The DEEM-FCID™ analyses estimate the
dietary exposure of the U.S. population and various population
subgroups.  The results reported in Table 3 are for the general U.S.
Population, all infants (<1 year old), children 1-2, children 3-5,
children 6-12, youth 13-19, females 13-49, adults 20-49, and adults 50+
years.  

Results of Acute Dietary Exposure Analysis

A toxic effect attributable to a single exposure was not seen in the
available toxicology database for boscalid; therefore, an acute dietary
risk assessment is not required.

Results of Chronic Dietary (Food and Drinking Water) Exposure Analysis

The chronic exposure and risk estimates for the general U.S. population
and all population subgroups are below 100% of the cPAD.  The most
highly exposed subgroup is Children 1–2 years of age which utilizes
33% of the cPAD.  The general U.S. population utilizes 10% of the cPAD. 
The detailed results from the chronic dietary exposure and risk
assessment are summarized in Table 2, below.

Results of Cancer Dietary Exposure Analysis

The CARC classified boscalid as demonstrating “suggestive evidence of
carcinogenicity.”  Evidence of carcinogenicity was seen in males
(significant trend and pair-wise at the high dose) and in females 
(trend only), however in both sexes no malignancies were seen, only
benign tumors were observed at dose levels above the dose level used to
establish the cPAD.  The CARC noted that changes in organ weights,
clinical chemistry, and non-neoplastic lesions support the thyroid as a
target.  Additionally, there is no concern for mutagencity.  The CARC
has indicated that quantification of human cancer risk is not required;
therefore, a cancer dietary exposure and risk assessment was not
conducted.

Table 2.  Summary of Dietary Exposure and Risk for Boscalid

(Food and Drinking Water)

Population Subgroup*	

Acute Dietary

(95th Percentile)	

Chronic Dietary	

Cancer

	

Dietary Exposure (mg/kg/day)	

% aPAD	

Dietary Exposure

(mg/kg/day)	

% cPAD	

Dietary Exposure

(mg/kg/day)	

Risk

General U.S. Population	N/A

	N/A

	

0.021804	10	

N/A	

N/A

All Infants (< 1 year old)

	

0.049396	23

Children 1-2 years old

	

0.072413	33

Children 3-5 years old

	

0.050831	23

Children 6-12 years old

	

0.026510	12

Youth 13-19 years old

	

0.015109	6.9

Adults 20-49 years old

	

0.016619	7.6

Adults 50+ years old

	

0.018459	8.5

Females 13-49 years old

	

0.016827	7.7

VII.	Characterization of Inputs/Outputs

HED conducted an unrefined dietary risk assessment for boscalid.  The
assessment assumes that all commodities with boscalid tolerances contain
residues of boscalid at the tolerance level.  When available, data from
processing studies were used to estimate residues in processed
commodities; however, in the absence of data, DEEM default processing
factors were incorporated into the assessment.  Lastly, the highest
modeled estimate of residues in drinking water was used in the
assessment.  Based on the conservative inputs into the analysis, it is
unlikely that the assessment will underestimate chronic dietary risks
from the proposed and existing uses of boscalid. 

Additional refinements, including the use of percent crop treated
information and monitoring data, could be incorporated into the
assessment.  However, as risk estimates are not of concern, a more
highly refined assessment is not needed at this time.

VIII.	Conclusions

A chronic dietary exposure and risk assessment was conducted for the
proposed and existing food uses of boscalid combined with estimated
residues of boscalid in drinking water.  The risk estimates for the
general U.S. population and all population subgroups are below HED’s
level of concern.

List of Attachments

1.  Boscalid Chronic Residue Input File

2.  Results of Chronic Dietary Exposure Analysis

Attachment 1:  Boscalid Chronic Residue Input File

DEEM/FCID Version 2.03

Chronic NOAEL: 21.8 mg/kg bw/day

Chronic Population Adjusted Dose (cPAD):  0.218 mg/kg bw/day

Filename:

C:\Documents and
Settings\ddotson\MyDocuments\DEEMFCID\Boscalid\Boscalid2008.R98

Date created/last modified: 10-21-2008/15:24:58/8

------------------------------------------------------------------------
----

  EPA    Crop                                   Def Res     Adj.Factors 
 Comment

  Code    Grp  Commodity Name                    (ppm)       #1    #2   

-------- ---- -------------------------------  ----------  ------ ------

01010500 1AB  Beet, garden, roots                0.100000   1.000  1.000
 

01010501 1AB  Beet, garden, roots-babyfood       0.100000   1.000  1.000
 

01010520 1A   Beet, sugar                        0.100000   1.000  1.000
 

01010521 1A   Beet, sugar-babyfood               0.100000   1.000  1.000
 

01010530 1A   Beet, sugar, molasses              0.100000   1.000  1.000
 

01010531 1A   Beet, sugar, molasses-babyfood     0.100000   1.000  1.000
 

01010670 1AB  Burdock                            1.000000   1.000  1.000
 

01010780 1AB  Carrot                             1.000000   1.000  1.000
 

01010781 1AB  Carrot-babyfood                    1.000000   1.000  1.000
 

01010790 1AB  Carrot, juice                      1.000000   1.000  1.000
 

01010840 1AB  Celeriac                           1.000000   1.000  1.000
 

01011000 1AB  Chicory, roots                     1.000000   1.000  1.000
 

01011680 1AB  Ginseng, dried                     1.000000   1.000  1.000
 

01011900 1AB  Horseradish                        1.000000   1.000  1.000
 

01012500 1AB  Parsley, turnip rooted             1.000000   1.000  1.000
 

01012510 1AB  Parsnip                            1.000000   1.000  1.000
 

01012511 1AB  Parsnip-babyfood                   1.000000   1.000  1.000
 

01013140 1AB  Radish, roots                      0.100000   1.000  1.000
 

01013160 1AB  Radish, Oriental, roots            1.000000   1.000  1.000
 

01013270 1AB  Rutabaga                           1.000000   1.000  1.000
 

01013310 1AB  Salsify, roots                     1.000000   1.000  1.000
 

01013880 1AB  Turnip, roots                      0.100000   1.000  1.000
 

01030150 1CD  Arrowroot, flour                   0.050000   1.000  1.000
 

01030151 1CD  Arrowroot, flour-babyfood          0.050000   1.000  1.000
 

01030170 1CD  Artichoke, Jerusalem               0.050000   1.000  1.000
 

01030820 1CD  Cassava                            0.050000   1.000  1.000
 

01030821 1CD  Cassava-babyfood                   0.050000   1.000  1.000
 

01031390 1CD  Dasheen, corm                      0.050000   1.000  1.000
 

01031660 1CD  Ginger                             0.050000   1.000  1.000
 

01031661 1CD  Ginger-babyfood                    0.050000   1.000  1.000
 

01031670 1CD  Ginger, dried                      0.050000   1.000  1.000
 

01032960 1C   Potato, chips                      0.050000   1.000  1.000
 

01032970 1C   Potato, dry (granules/ flakes)     0.050000   6.500  1.000
 

01032971 1C   Potato, dry (granules/ flakes)-b   0.050000   6.500  1.000
 

01032980 1C   Potato, flour                      0.050000   6.500  1.000
 

01032981 1C   Potato, flour-babyfood             0.050000   6.500  1.000
 

01032990 1C   Potato, tuber, w/peel              0.050000   1.000  1.000
 

01032991 1C   Potato, tuber, w/peel-babyfood     0.050000   1.000  1.000
 

01033000 1C   Potato, tuber, w/o peel            0.050000   1.000  1.000
 

01033001 1C   Potato, tuber, w/o peel-babyfood   0.050000   1.000  1.000
 

01033660 1CD  Sweet potato                       0.050000   1.000  1.000
 

01033661 1CD  Sweet potato-babyfood              0.050000   1.000  1.000
 

01033710 1CD  Tanier, corm                       0.050000   1.000  1.000
 

01033870 1CD  Turmeric                           0.050000   1.000  1.000
 

01034060 1CD  Yam, true                          0.050000   1.000  1.000
 

01034070 1CD  Yam bean                           0.050000   1.000  1.000
 

02000510 2    Beet, garden, tops                 0.100000   1.000  1.000
 

02001010 2    Chicory, tops                      0.100000   1.000  1.000
 

02001400 2    Dasheen, leaves                    0.100000   1.000  1.000
 

02003150 2    Radish, tops                       0.100000   1.000  1.000
 

02003170 2    Radish, Oriental, tops             0.100000   1.000  1.000
 

02003320 2    Salsify, tops                      0.100000   1.000  1.000
 

03001640 3    Garlic                             3.000000   1.000  1.000
 

03001650 3    Garlic, dried                      3.000000   1.000  1.000
 

03001651 3    Garlic, dried-babyfood             3.000000   1.000  1.000
 

03001980 3    Leek                               3.000000   1.000  1.000
 

03002370 3    Onion, dry bulb                    3.000000   1.000  1.000
 

03002371 3    Onion, dry bulb-babyfood           3.000000   1.000  1.000
 

03002380 3    Onion, dry bulb, dried             3.000000   9.000  1.000
 

03002381 3    Onion, dry bulb, dried-babyfood    3.000000   9.000  1.000
 

03002390 3    Onion, green                       3.000000   1.000  1.000
 

03003380 3    Shallot                            3.000000   1.000  1.000
 

04010050 4A   Amaranth, leafy                   60.000000   1.000  1.000
 

04010180 4A   Arugula                           60.000000   1.000  1.000
 

04011040 4A   Chrysanthemum, garland            60.000000   1.000  1.000
 

04011330 4A   Cress, garden                     60.000000   1.000  1.000
 

04011340 4A   Cress, upland                     60.000000   1.000  1.000
 

04011380 4A   Dandelion, leaves                 60.000000   1.000  1.000
 

04011500 4A   Endive                            60.000000   1.000  1.000
 

04012040 4A   Lettuce, head                      6.500000   1.000  1.000
 

04012050 4A   Lettuce, leaf                     11.000000   1.000  1.000
 

04012480 4A   Parsley, leaves                   60.000000   1.000  1.000
 

04013130 4A   Radicchio                         60.000000   1.000  1.000
 

04013550 4A   Spinach                           60.000000   1.000  1.000
 

04013551 4A   Spinach-babyfood                  60.000000   1.000  1.000
 

04020760 4B   Cardoon                           45.000000   1.000  1.000
 

04020850 4B   Celery                            45.000000   1.000  1.000
 

04020851 4B   Celery-babyfood                   45.000000   1.000  1.000
 

04020860 4B   Celery, juice                     45.000000   1.000  1.000
 

04020870 4B   Celtuce                           45.000000   1.000  1.000
 

04021520 4B   Fennel, Florence                  45.000000   1.000  1.000
 

04023220 4B   Rhubarb                           45.000000   1.000  1.000
 

04023670 4B   Swiss chard                       45.000000   1.000  1.000
 

05010610 5A   Broccoli                           3.000000   1.000  1.000
 

05010611 5A   Broccoli-babyfood                  3.000000   1.000  1.000
 

05010620 5A   Broccoli, Chinese                  3.000000   1.000  1.000
 

05010640 5A   Brussels sprouts                   3.000000   1.000  1.000
 

05010690 5A   Cabbage                            3.000000   1.000  1.000
 

05010710 5A   Cabbage, Chinese, napa             3.000000   1.000  1.000
 

05010720 5A   Cabbage, Chinese, mustard          3.000000   1.000  1.000
 

05010830 5A   Cauliflower                        3.000000   1.000  1.000
 

05011960 5A   Kohlrabi                           3.000000   1.000  1.000
 

05020630 5B   Broccoli raab                     18.000000   1.000  1.000
 

05020700 5B   Cabbage, Chinese, bok choy        18.000000   1.000  1.000
 

05021170 5B   Collards                          18.000000   1.000  1.000
 

05021940 5B   Kale                              18.000000   1.000  1.000
 

05022290 5B   Mustard greens                    18.000000   1.000  1.000
 

05023180 5B   Rape greens                       18.000000   1.000  1.000
 

05023890 5B   Turnip, greens                    18.000000   1.000  1.000
 

06003470 6    Soybean, seed                      0.100000   1.000  1.000
 

06003480 6    Soybean, flour                     0.100000   1.000  1.000
 

06003481 6    Soybean, flour-babyfood            0.100000   1.000  1.000
 

06003490 6    Soybean, soy milk                  0.100000   1.000  1.000
 

06003491 6    Soybean, soy milk-babyfood or in   0.100000   1.000  1.000
 

06003500 6    Soybean, oil                       0.100000   1.000  1.000
 

06003501 6    Soybean, oil-babyfood              0.100000   1.000  1.000
 

06010430 6A   Bean, snap, succulent              1.600000   1.000  1.000
 

06010431 6A   Bean, snap, succulent-babyfood     1.600000   1.000  1.000
 

06012570 6A   Pea, edible podded, succulent      1.600000   1.000  1.000
 

06020310 6B   Bean, broad, succulent             0.600000   1.000  1.000
 

06020370 6B   Bean, lima, succulent              0.600000   1.000  1.000
 

06022550 6B   Pea, succulent                     0.600000   1.000  1.000
 

06022551 6B   Pea, succulent-babyfood            0.600000   1.000  1.000
 

06022590 6B   Pea, pigeon, succulent             0.600000   1.000  1.000
 

06030300 6C   Bean, black, seed                  2.500000   1.000  1.000
 

06030320 6C   Bean, broad, seed                  2.500000   1.000  1.000
 

06030350 6C   Bean,  great northern, seed        2.500000   1.000  1.000
 

06030360 6C   Bean, kidney, seed                 2.500000   1.000  1.000
 

06030380 6C   Bean, lima, seed                   2.500000   1.000  1.000
 

06030390 6C   Bean, mung, seed                   2.500000   1.000  1.000
 

06030400 6C   Bean, navy, seed                   2.500000   1.000  1.000
 

06030410 6C   Bean, pink, seed                   2.500000   1.000  1.000
 

06030420 6C   Bean, pinto, seed                  2.500000   1.000  1.000
 

06030980 6C   Chickpea, seed                     2.500000   1.000  1.000
 

06030981 6C   Chickpea, seed-babyfood            2.500000   1.000  1.000
 

06030990 6C   Chickpea, flour                    2.500000   1.000  1.000
 

06031820 6C   Guar, seed                         2.500000   1.000  1.000
 

06031821 6C   Guar, seed-babyfood                2.500000   1.000  1.000
 

06032030 6C   Lentil, seed                       2.500000   1.000  1.000
 

06032560 6C   Pea, dry                           2.500000   1.000  1.000
 

06032561 6C   Pea, dry-babyfood                  2.500000   1.000  1.000
 

06032580 6C   Pea, pigeon, seed                  2.500000   1.000  1.000
 

08001480 8    Eggplant                           1.200000   1.000  1.000
 

08002340 8    Okra                               1.200000   1.000  1.000
 

08002700 8    Pepper, bell                       1.200000   1.000  1.000
 

08002701 8    Pepper, bell-babyfood              1.200000   1.000  1.000
 

08002710 8    Pepper, bell, dried                1.200000   1.000  1.000
 

08002711 8    Pepper, bell, dried-babyfood       1.200000   1.000  1.000
 

08002720 8    Pepper, nonbell                    1.200000   1.000  1.000
 

08002721 8    Pepper, nonbell-babyfood           1.200000   1.000  1.000
 

08002730 8    Pepper, nonbell, dried             1.200000   1.000  1.000
 

08003740 8    Tomatillo                          1.200000   1.000  1.000
 

08003750 8    Tomato                             1.200000   1.000  1.000
 

08003751 8    Tomato-babyfood                    1.200000   1.000  1.000
 

08003760 8    Tomato, paste                      1.200000   1.000  1.000
 

08003761 8    Tomato, paste-babyfood             1.200000   1.000  1.000
 

08003770 8    Tomato, puree                      1.200000   1.000  1.000
 

08003771 8    Tomato, puree-babyfood             1.200000   1.000  1.000
 

08003780 8    Tomato, dried                      1.200000  14.300  1.000
 

08003781 8    Tomato, dried-babyfood             1.200000  14.300  1.000
 

08003790 8    Tomato, juice                      1.200000   1.000  1.000
 

09010750 9A   Cantaloupe                         1.600000   1.000  1.000
 

09010800 9A   Casaba                             1.600000   1.000  1.000
 

09011870 9A   Honeydew melon                     1.600000   1.000  1.000
 

09013990 9A   Watermelon                         1.600000   1.000  1.000
 

09014000 9A   Watermelon, juice                  1.600000   1.000  1.000
 

09020210 9B   Balsam pear                        1.600000   1.000  1.000
 

09020880 9B   Chayote, fruit                     1.600000   1.000  1.000
 

09021020 9B   Chinese waxgourd                   1.600000   1.000  1.000
 

09021350 9B   Cucumber                           0.500000   1.000  1.000
 

09023080 9B   Pumpkin                            1.600000   1.000  1.000
 

09023090 9B   Pumpkin, seed                      1.600000   1.000  1.000
 

09023560 9B   Squash, summer                     1.600000   1.000  1.000
 

09023561 9B   Squash, summer-babyfood            1.600000   1.000  1.000
 

09023570 9B   Squash, winter                     1.600000   1.000  1.000
 

09023571 9B   Squash, winter-babyfood            1.600000   1.000  1.000
 

10003690 10   Tangerine                          2.000000   1.000  1.000
 

10003700 10   Tangerine, juice                   2.000000   2.300  1.000
 

11000070 11   Apple, fruit with peel             3.000000   1.000  1.000
 

11000080 11   Apple, peeled fruit                3.000000   1.000  1.000
 

11000081 11   Apple, peeled fruit-babyfood       3.000000   1.000  1.000
 

11000090 11   Apple, dried                       3.000000   8.000  1.000
 

11000091 11   Apple, dried-babyfood              3.000000   8.000  1.000
 

11000100 11   Apple, juice                       3.000000   1.000  1.000
 

11000101 11   Apple, juice-babyfood              3.000000   1.000  1.000
 

11000110 11   Apple, sauce                       3.000000   1.000  1.000
 

11000111 11   Apple, sauce-babyfood              3.000000   1.000  1.000
 

11001290 11   Crabapple                          3.000000   1.000  1.000
 

11002100 11   Loquat                             3.000000   1.000  1.000
 

11002660 11   Pear                               3.000000   1.000  1.000
 

11002661 11   Pear-babyfood                      3.000000   1.000  1.000
 

11002670 11   Pear, dried                        3.000000   6.250  1.000
 

11002680 11   Pear, juice                        3.000000   1.000  1.000
 

11002681 11   Pear, juice-babyfood               3.000000   1.000  1.000
 

11003100 11   Quince                             3.000000   1.000  1.000
 

12000120 12   Apricot                            1.700000   1.000  1.000
 

12000121 12   Apricot-babyfood                   1.700000   1.000  1.000
 

12000130 12   Apricot, dried                     1.700000   6.000  1.000
 

12000140 12   Apricot, juice                     1.700000   1.000  1.000
 

12000141 12   Apricot, juice-babyfood            1.700000   1.000  1.000
 

12000900 12   Cherry                             1.700000   1.000  1.000
 

12000901 12   Cherry-babyfood                    1.700000   1.000  1.000
 

12000910 12   Cherry, juice                      1.700000   1.500  1.000
 

12000911 12   Cherry, juice-babyfood             1.700000   1.500  1.000
 

12002300 12   Nectarine                          1.700000   1.000  1.000
 

12002600 12   Peach                              1.700000   1.000  1.000
 

12002601 12   Peach-babyfood                     1.700000   1.000  1.000
 

12002610 12   Peach, dried                       1.700000   7.000  1.000
 

12002611 12   Peach, dried-babyfood              1.700000   7.000  1.000
 

12002620 12   Peach, juice                       1.700000   1.000  1.000
 

12002621 12   Peach, juice-babyfood              1.700000   1.000  1.000
 

12002850 12   Plum                               1.700000   1.000  1.000
 

12002851 12   Plum-babyfood                      1.700000   1.000  1.000
 

12002860 12   Plum, prune, fresh                 1.700000   1.000  1.000
 

12002861 12   Plum, prune, fresh-babyfood        1.700000   1.000  1.000
 

12002870 12   Plum, prune, dried                 1.700000   1.000  1.000
 

12002871 12   Plum, prune, dried-babyfood        1.700000   1.000  1.000
 

12002880 12   Plum, prune, juice                 1.700000   1.400  1.000
 

12002881 12   Plum, prune, juice-babyfood        1.700000   1.400  1.000
 

13010550 13A  Blackberry                         6.000000   1.000  1.000
 

13010560 13A  Blackberry, juice                  6.000000   1.000  1.000
 

13010561 13A  Blackberry, juice-babyfood         6.000000   1.000  1.000
 

13010580 13A  Boysenberry                        6.000000   1.000  1.000
 

13011420 13A  Dewberry                           6.000000   1.000  1.000
 

13012080 13A  Loganberry                         6.000000   1.000  1.000
 

13013200 13A  Raspberry                          6.000000   1.000  1.000
 

13013201 13A  Raspberry-babyfood                 6.000000   1.000  1.000
 

13013210 13A  Raspberry, juice                   6.000000   1.000  1.000
 

13013211 13A  Raspberry, juice-babyfood          6.000000   1.000  1.000
 

13020570 13B  Blueberry                         10.000000   1.000  1.000
 

13020571 13B  Blueberry-babyfood                10.000000   1.000  1.000
 

13021360 13B  Currant                           10.000000   1.000  1.000
 

13021370 13B  Currant, dried                    10.000000   1.000  1.000
 

13021490 13B  Elderberry                        10.000000   1.000  1.000
 

13021740 13B  Gooseberry                        10.000000   1.000  1.000
 

13021910 13B  Huckleberry                       10.000000   1.000  1.000
 

14000030 14   Almond                             0.700000   1.000  1.000
 

14000031 14   Almond-babyfood                    0.700000   1.000  1.000
 

14000040 14   Almond, oil                        0.700000   1.000  1.000
 

14000041 14   Almond, oil-babyfood               0.700000   1.000  1.000
 

14000590 14   Brazil nut                         0.700000   1.000  1.000
 

14000680 14   Butternut                          0.700000   1.000  1.000
 

14000810 14   Cashew                             0.700000   1.000  1.000
 

14000920 14   Chestnut                           0.700000   1.000  1.000
 

14001550 14   Filbert                            0.700000   1.000  1.000
 

14001560 14   Filbert, oil                       0.700000   1.000  1.000
 

14001850 14   Hickory nut                        0.700000   1.000  1.000
 

14002130 14   Macadamia nut                      0.700000   1.000  1.000
 

14002690 14   Pecan                              0.700000   1.000  1.000
 

14002820 14   Pistachio                          0.700000   1.000  1.000
 

14003910 14   Walnut                             0.700000   1.000  1.000
 

15000250 15   Barley, pearled barley             0.200000   1.000  1.000
 

15000251 15   Barley, pearled barley-babyfood    0.200000   1.000  1.000
 

15000260 15   Barley, flour                      0.200000   1.000  1.000
 

15000261 15   Barley, flour-babyfood             0.200000   1.000  1.000
 

15000270 15   Barley, bran                       0.200000   1.000  1.000
 

15000650 15   Buckwheat                          0.200000   1.000  1.000
 

15000660 15   Buckwheat, flour                   0.200000   1.000  1.000
 

15001200 15   Corn, field, flour                 0.200000   1.000  1.000
 

15001201 15   Corn, field, flour-babyfood        0.200000   1.000  1.000
 

15001210 15   Corn, field, meal                  0.200000   1.000  1.000
 

15001211 15   Corn, field, meal-babyfood         0.200000   1.000  1.000
 

15001220 15   Corn, field, bran                  0.200000   1.000  1.000
 

15001230 15   Corn, field, starch                0.200000   1.000  1.000
 

15001231 15   Corn, field, starch-babyfood       0.200000   1.000  1.000
 

15001240 15   Corn, field, syrup                 0.200000   1.500  1.000
 

15001241 15   Corn, field, syrup-babyfood        0.200000   1.500  1.000
 

15001250 15   Corn, field, oil                   0.200000   1.000  1.000
 

15001251 15   Corn, field, oil-babyfood          0.200000   1.000  1.000
 

15002260 15   Millet, grain                      0.200000   1.000  1.000
 

15002310 15   Oat, bran                          0.200000   1.000  1.000
 

15002320 15   Oat, flour                         0.200000   1.000  1.000
 

15002321 15   Oat, flour-babyfood                0.200000   1.000  1.000
 

15002330 15   Oat, groats/rolled oats            0.200000   1.000  1.000
 

15002331 15   Oat, groats/rolled oats-babyfood   0.200000   1.000  1.000
 

15003230 15   Rice, white                        0.200000   1.000  1.000
 

15003231 15   Rice, white-babyfood               0.200000   1.000  1.000
 

15003240 15   Rice, brown                        0.200000   1.000  1.000
 

15003241 15   Rice, brown-babyfood               0.200000   1.000  1.000
 

15003250 15   Rice, flour                        0.200000   1.000  1.000
 

15003251 15   Rice, flour-babyfood               0.200000   1.000  1.000
 

15003260 15   Rice, bran                         0.200000   1.000  1.000
 

15003261 15   Rice, bran-babyfood                0.200000   1.000  1.000
 

15003280 15   Rye, grain                         0.200000   1.000  1.000
 

15003290 15   Rye, flour                         0.200000   1.000  1.000
 

15003440 15   Sorghum, grain                     0.200000   1.000  1.000
 

15003450 15   Sorghum, syrup                     0.200000   1.000  1.000
 

15003810 15   Triticale, flour                   0.200000   1.000  1.000
 

15003811 15   Triticale, flour-babyfood          0.200000   1.000  1.000
 

15004010 15   Wheat, grain                       0.200000   1.000  1.000
 

15004011 15   Wheat, grain-babyfood              0.200000   1.000  1.000
 

15004020 15   Wheat, flour                       0.200000   1.000  1.000
 

15004021 15   Wheat, flour-babyfood              0.200000   1.000  1.000
 

15004030 15   Wheat, germ                        0.200000   1.000  1.000
 

15004040 15   Wheat, bran                        0.200000   1.000  1.000
 

15004050 15   Wild rice                          0.200000   1.000  1.000
 

19010280 19A  Basil, fresh leaves               40.000000   1.000  1.000
 

19010281 19A  Basil, fresh leaves-babyfood      40.000000   1.000  1.000
 

19010290 19A  Basil, dried leaves              190.000000   1.000  1.000
 

19010291 19A  Basil, dried leaves-babyfood     190.000000   1.000  1.000
 

19011030 19A  Chive                             40.000000   1.000  1.000
 

19011180 19A  Coriander, leaves                 40.000000   1.000  1.000
 

19011181 19A  Coriander, leaves-babyfood        40.000000   1.000  1.000
 

19011440 19A  Dillweed                          40.000000   1.000  1.000
 

19011840 19A  Herbs, other                      40.000000   1.000  1.000
 

19011841 19A  Herbs, other-babyfood             40.000000   1.000  1.000
 

19012020 19A  Lemongrass                        40.000000   1.000  1.000
 

19012200 19A  Marjoram                          40.000000   1.000  1.000
 

19012201 19A  Marjoram-babyfood                 40.000000   1.000  1.000
 

19012490 19A  Parsley, dried leaves            190.000000   1.000  1.000
 

19012491 19A  Parsley, dried leaves-babyfood   190.000000   1.000  1.000
 

19013340 19A  Savory                            40.000000   1.000  1.000
 

19021430 19B  Dill, seed                       140.000000   1.000  1.000
 

20001630 20   Flaxseed, oil                      5.000000   1.000  1.000
 

20003190 20   Rapeseed, oil                      5.000000   1.000  1.000
 

20003191 20   Rapeseed, oil-babyfood             5.000000   1.000  1.000
 

20003640 20   Sunflower, seed                    0.600000   1.000  1.000
 

20003650 20   Sunflower, oil                     0.600000   1.000  1.000
 

20003651 20   Sunflower, oil-babyfood            0.600000   1.000  1.000
 

21000440 M    Beef, meat                         0.100000   1.000  1.000
 

21000441 M    Beef, meat-babyfood                0.100000   1.000  1.000
 

21000450 M    Beef, meat, dried                  0.100000   1.920  1.000
 

21000460 M    Beef, meat byproducts              0.350000   1.000  1.000
 

21000461 M    Beef, meat byproducts-babyfood     0.350000   1.000  1.000
 

21000470 M    Beef, fat                          0.300000   1.000  1.000
 

21000471 M    Beef,fat-babyfood                  0.300000   1.000  1.000
 

21000480 M    Beef, kidney                       0.350000   1.000  1.000
 

21000490 M    Beef, liver                        0.350000   1.000  1.000
 

21000491 M    Beef, liver-babyfood               0.350000   1.000  1.000
 

23001690 M    Goat, meat                         0.100000   1.000  1.000
 

23001700 M    Goat, meat byproducts              0.350000   1.000  1.000
 

23001710 M    Goat, fat                          0.300000   1.000  1.000
 

23001720 M    Goat, kidney                       0.350000   1.000  1.000
 

23001730 M    Goat, liver                        0.350000   1.000  1.000
 

24001890 M    Horse, meat                        0.100000   1.000  1.000
 

25002900 M    Pork, meat                         0.050000   1.000  1.000
 

25002901 M    Pork, meat-babyfood                0.050000   1.000  1.000
 

25002910 M    Pork, skin                         0.100000   1.000  1.000
 

25002920 M    Pork, meat byproducts              0.100000   1.000  1.000
 

25002921 M    Pork, meat byproducts-babyfood     0.100000   1.000  1.000
 

25002930 M    Pork, fat                          0.100000   1.000  1.000
 

25002931 M    Pork, fat-babyfood                 0.100000   1.000  1.000
 

25002940 M    Pork, kidney                       0.100000   1.000  1.000
 

25002950 M    Pork, liver                        0.100000   1.000  1.000
 

26003390 M    Sheep, meat                        0.100000   1.000  1.000
 

26003391 M    Sheep, meat-babyfood               0.100000   1.000  1.000
 

26003400 M    Sheep, meat byproducts             0.350000   1.000  1.000
 

26003410 M    Sheep, fat                         0.300000   1.000  1.000
 

26003411 M    Sheep, fat-babyfood                0.300000   1.000  1.000
 

26003420 M    Sheep, kidney                      0.350000   1.000  1.000
 

26003430 M    Sheep, liver                       0.350000   1.000  1.000
 

27002220 D    Milk, fat                          0.100000   1.000  1.000
 

27002221 D    Milk, fat - baby food/infant for   0.100000   1.000  1.000
 

27012230 D    Milk, nonfat solids                0.100000   1.000  1.000
 

27012231 D    Milk, nonfat solids-baby food/in   0.100000   1.000  1.000
 

27022240 D    Milk, water                        0.100000   1.000  1.000
 

27022241 D    Milk, water-babyfood/infant form   0.100000   1.000  1.000
 

27032251 D    Milk, sugar (lactose)-baby food/   0.100000   1.000  1.000
 

40000930 P    Chicken, meat                      0.050000   1.000  1.000
 

40000931 P    Chicken, meat-babyfood             0.050000   1.000  1.000
 

40000940 P    Chicken, liver                     0.100000   1.000  1.000
 

40000950 P    Chicken, meat byproducts           0.100000   1.000  1.000
 

40000951 P    Chicken, meat byproducts-babyfoo   0.100000   1.000  1.000
 

40000960 P    Chicken, fat                       0.050000   1.000  1.000
 

40000961 P    Chicken, fat-babyfood              0.050000   1.000  1.000
 

40000970 P    Chicken, skin                      0.050000   1.000  1.000
 

40000971 P    Chicken, skin-babyfood             0.050000   1.000  1.000
 

50003820 P    Turkey, meat                       0.050000   1.000  1.000
 

50003821 P    Turkey, meat-babyfood              0.050000   1.000  1.000
 

50003830 P    Turkey, liver                      0.100000   1.000  1.000
 

50003831 P    Turkey, liver-babyfood             0.100000   1.000  1.000
 

50003840 P    Turkey, meat byproducts            0.100000   1.000  1.000
 

50003841 P    Turkey, meat byproducts-babyfood   0.100000   1.000  1.000
 

50003850 P    Turkey, fat                        0.050000   1.000  1.000
 

50003851 P    Turkey, fat-babyfood               0.050000   1.000  1.000
 

50003860 P    Turkey, skin                       0.050000   1.000  1.000
 

50003861 P    Turkey, skin-babyfood              0.050000   1.000  1.000
 

60003010 P    Poultry, other, meat               0.050000   1.000  1.000
 

60003020 P    Poultry, other, liver              0.100000   1.000  1.000
 

60003030 P    Poultry, other, meat byproducts    0.100000   1.000  1.000
 

60003040 P    Poultry, other, fat                0.050000   1.000  1.000
 

60003050 P    Poultry, other, skin               0.050000   1.000  1.000
 

70001450 P    Egg, whole                         0.020000   1.000  1.000
 

70001451 P    Egg, whole-babyfood                0.020000   1.000  1.000
 

70001460 P    Egg, white                         0.020000   1.000  1.000
 

70001461 P    Egg, white (solids)-babyfood       0.020000   1.000  1.000
 

70001470 P    Egg, yolk                          0.020000   1.000  1.000
 

70001471 P    Egg, yolk-babyfood                 0.020000   1.000  1.000
 

86010000 O    Water, direct, all sources         0.029600   1.000  1.000
 

86020000 O    Water, indirect, all sources       0.029600   1.000  1.000
 

95000200 O    Avocado                            1.500000   1.000  1.000
 

95000230 O    Banana                             0.400000   1.000  1.000
 

95000231 O    Banana-babyfood                    0.400000   1.000  1.000
 

95000240 O    Banana, dried                      0.400000   3.900  1.000
 

95000241 O    Banana, dried-babyfood             0.400000   3.900  1.000
 

95000740 O    Canistel                           1.500000   1.000  1.000
 

95001150 O    Coffee, roasted bean               0.050000   1.000  1.000
 

95001160 O    Coffee, instant                    0.050000   1.000  1.000
 

95001280 O    Cottonseed, oil                    1.000000   1.000  1.000
 

95001281 O    Cottonseed, oil-babyfood           1.000000   1.000  1.000
 

95001750 O    Grape                              3.500000   1.000  1.000
 

95001760 O    Grape, juice                       3.500000   1.200  1.000
 

95001761 O    Grape, juice-babyfood              3.500000   1.200  1.000
 

95001770 O    Grape, leaves                      3.500000   1.000  1.000
 

95001780 O    Grape, raisin                      8.500000   1.000  1.000
 

95001790 O    Grape, wine and sherry             3.500000   1.000  1.000
 

95001880 O    Hop                               35.000000   1.000  1.000
 

95002150 O    Mango                              1.500000   1.000  1.000
 

95002151 O    Mango-babyfood                     1.500000   1.000  1.000
 

95002160 O    Mango, dried                       1.500000   1.000  1.000
 

95002170 O    Mango, juice                       1.500000   1.000  1.000
 

95002171 O    Mango, juice-babyfood              1.500000   1.000  1.000
 

95002450 O    Papaya                             1.500000   1.000  1.000
 

95002451 O    Papaya-babyfood                    1.500000   1.000  1.000
 

95002460 O    Papaya, dried                      1.500000   1.800  1.000
 

95002470 O    Papaya, juice                      1.500000   1.500  1.000
 

95002630 O    Peanut                             0.050000   1.000  1.000
 

95002640 O    Peanut, butter                     0.050000   1.890  1.000
 

95002650 O    Peanut, oil                        0.150000   1.000  1.000
 

95002750 O    Peppermint                        30.000000   1.000  1.000
 

95002760 O    Peppermint, oil                   30.000000   1.000  1.000
 

95002830 O    Plantain                           0.400000   1.000  1.000
 

95002840 O    Plantain, dried                    0.400000   3.900  1.000
 

95003330 O    Sapote, Mamey                      1.500000   1.000  1.000
 

95003520 O    Spearmint                         30.000000   1.000  1.000
 

95003530 O    Spearmint, oil                    30.000000   1.000  1.000
 

95003590 O    Strawberry                         4.500000   1.000  1.000
 

95003591 O    Strawberry-babyfood                4.500000   1.000  1.000
 

95003600 O    Strawberry, juice                  4.500000   1.000  1.000
 

95003601 O    Strawberry, juice-babyfood         4.500000   1.000  1.000
 

Attachment 2:  Results of Chronic Dietary Exposure Analysis

DEEM/FCID Version 2.03

Chronic NOAEL: 21.8 mg/kg bw/day

Chronic Population Adjusted Dose (cPAD):  0.218 mg/kg bw/day

Residue file name:

C:\Documents and Settings\ddotson\My
Documents\DEEMFCID\Boscalid\Boscalid2008.R98

Analysis Date 10-20-2008/16:35:06     Residue file dated:
10-20-2008/16:32:44/8

========================================================================
=======

                    Total exposure by population subgroup

------------------------------------------------------------------------
-------

                                                    Total Exposure

                                        
-----------------------------------

          Population                         mg/kg             Percent
of   

           Subgroup                       body wt/day             Rfd   
   

--------------------------------------   -------------      
---------------

U.S. Population (total)                     0.021804               
10.0%

U.S. Population (spring season)             0.021975               
10.1%

U.S. Population (summer season)             0.021458                
9.8%

U.S. Population (autumn season)             0.021761               
10.0%

U.S. Population (winter season)             0.022045               
10.1%

Northeast region                            0.023648               
10.8%

Midwest region                              0.021067                
9.7%

Southern region                             0.019494                
8.9%

Western region                              0.024603               
11.3%

Hispanics                                   0.022603               
10.4%

Non-hispanic whites                         0.021311                
9.8%

Non-hispanic blacks                         0.021193                
9.7%

Non-hisp/non-white/non-black                0.029699               
13.6%

All infants (< 1 year)                      0.049396               
22.7%

Nursing infants                             0.025360               
11.6%

Non-nursing infants                         0.058521               
26.8%

Children 1-6  yrs                           0.055524               
25.5%

Children 7-12 yrs                           0.024830               
11.4%

Females 13-19 (not preg or nursing)         0.014662                
6.7%

Females 20+ (not preg or nursing)           0.017977                
8.2%

Females 13-50 yrs                           0.017765                
8.1%

Females 13+ (preg/not nursing)              0.016769                
7.7%

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Females 13+ (nursing)                       0.021055                
9.7%

Males 13-19 yrs                             0.015524                
7.1%

Males 20+ yrs                               0.016514                
7.6%

Seniors 55+                                 0.018487                
8.5%

Children 1-2 yrs                            0.072413               
33.2%

Children 3-5 yrs                            0.050831               
23.3%

Children 6-12 yrs                           0.026510               
12.2%

Youth 13-19 yrs                             0.015109                
6.9%

Adults 20-49 yrs                            0.016619                
7.6%

Adults 50+ yrs                              0.018459                
8.5%

Females 13-49 yrs                           0.016827                
7.7%

------------------------------------------------------------------------
-------

Boscalid		DP Number: 357496	

PC Code:  128008		

Page   PAGE  1  of   NUMPAGES  17