Document ID: EPA-HQ-OPP-2016-0062-0070
Agency: epa
Document Type: Supporting & Related Material
Title: 
Posted Date: 2016-03-31T04:00Z

% Gender neutral or male specific values, except for female BTW and fat available
% Set sex=1 to access female parameters

SPECIES=1;
SEX=0;
PREG=0;
GDSTART=1;
PAFC=1;

%BWT and Volume fat specific to women
% Gompertz BWT Parameters (Luecke 2007)
% set Female BWT Parameters
B1=3.4;B2=2.07402;B3=1.504154;B5=34.8806;B6=0.2120837;B7=0.443786;
B4=2.672665;B8=0.31127;
AGE1=2.949004;AGE2=11;AGE3=21.86533;
BWSW=1; %Switch for age (set =0) or set (set =1) determination of BW
BWST=68; %Set value of BW (kg) Np=68, 1ST TRIMESTER=74, 3RD TRIMESTER=77
% set Female VFCb    
VF6=-1.273e-30;VF5=7.249e-25;VF4=-1.558e-19;VF3=1.540e-14;VF2=-6.787e-10;
VF1=1.401e-05;VF0=9.217e-02;

% Constant organ volumes
VBMC=0.021;	% Brown 1997 (red only, yellow is in adipose)
VDC=0.0003;
VPC=0.00148; 	% Young 2009, Brown 1997
VINTC=0.0091;	% Just small intestine (Brown 1997)

% HCT
HCTN=0.40; 	% 0.43 women, 0.47 men (Bresarb 1998); 40 from Abdjljalil et al

% Partitioning Coef. (Lowe 2009)
% CPF
PPLA=83; %PLACENTA =1/3 fat - placenta/fetus could include some bound CPF?
PAFC=19;
% CPF-oxon
PPLAO=11.2; %PLACENTA =2xrapid 
VVOL=0.075;  %ml/hr urine production in women

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