Document ID: EPA-HQ-OPP-2003-0129-0004
Agency: epa
Document Type: Supporting & Related Material
Title: 
Posted Date: 2005-08-15T04:00Z

Ellen
Connett,
Director
Fluoride
Action
Network
Pesticide
Project
82
Judson
Street,
Canton,
NY
13617
Reference:
Docket
ID
OPP­
2003­
0129;
Fluoxastrobin;
Notice
of
Filing
a
Pesticide
Petition
to
Establish
a
Tolerance
for
a
Certain
Pesticide
Chemical
in
or
on
Food
Your
Public
Docket
Comments,
Dated
4/
25/
03
Dear
Ms.
Connett:
This
letter
represents
the
Agency's
response
to
your
public
docket
comments
on
the
Notice
of
Filing
for
the
new
chemical
Fluoxastrobin.

You
commented
that;
"
References
were
not
given
for
the
studies
cited
in
this
Notice;
nor
were
they
available
in
the
Docket.
Without
this
information,
it
is
impossible
to
comment
on
the
findings
presented.
Examples:

1.
Several
genotoxicity
tests
were
conducted
2.
Acute
toxicity
studies
3.
An
oral
developmental
toxicity
study
in
rat
4.
An
oral
developmental
toxicity
study
in
rabbits
5.
A
2­
generation
study
in
rats
6.
Subchronic
toxicity
feeding
study
with
rats
over
90
days
7.
Subchronic
feeding
study
in
mice
over
14
weeks
8.
A
14­
week
feeding
study
in
dogs
9.
A
24­
month
chronic/
oncogenicity
feeding
study
in
rats
10.
Oncogenicity
study
in
the
mouse
11.
1­
year
feeding
study
with
dogs
12.
Metabolism
and
pharmacokinetic
studies
in
the
rats,
lactating
goats,
and
laying
hens
13.
Metabolite
studies."

In
response
to
your
comments,
the
Agency
is
herewith
transmitting
its
human
health
risk
assessment
(
dated
1/
24/
05)
titled
"
Fluoxastrobin:
Human
health
risk
assessment
for
proposed
uses
on
peanuts,
tuberous
and
corm
vegetables
(
subgroup
1C),
leaf
petiole
vegetables,
(
subgroup
4B),
fruiting
vegetables
(
group
8),
turf.
PC
code
028869.
Petition
No.
3F6556.
DP
Barcodes:
D292422,
D303256.
EPA
File
Symbol
No's
264­
TIT
)
Flouxastrobin
Technical),
and
264­
TIA
(
HEC
480
SC
Fungicide)".

If
you
still
wish
to
receive
copies
of
the
toxicological
studies
submitted
to
support
registration
of
this
new
chemical,
please
complete,
sign
and
date
the
enclosed
FIFRA
Section
10(
g)
form
titled
"
Affirmation
of
Non­
Multinational
Status"
(
we
also
faxed
this
form
to
you
on
7/
6/
05).
Please
return
it
to
my
attention
within
10
calendar
days
of
receipt
of
this
letter.
While
we
are
waiting
for
this
form
with
the
original
signature,
could
you
please
fax
the
completed
form
to
me
at
703­
308­
1825.

We
can
release
the
data
to
you
on
CD­
ROM
shortly
after
we
receive
the
original
signed
form.
You
have
30
days
from
the
date
of
this
letter
to
provide
comments
on
the
data
and
risk
assessment.
We
will
respond
to
your
comments
in
the
final
rule.

If
you
have
any
questions,
please
call
me
at
703­
308­
9443.

Sincerely,

Tony
Kish
Acting
Product
Manager
22
Fungicides
Branch,
Registration
Division
(
7505C)

enclosures:
Fluoxastrobin
human
health
risk
assessment
FIFRA
Section
10(
g)