Document ID: EPA-HQ-ORD-2003-0002-0001
Agency: epa
Document Type: Notice
Title: Framework for Application of the Toxicity Equivalence Methodology for Polychlorinated Dioxins, Furans, and Biphenyls in Ecological Risk Assessment (External Review Draft): Notice of Availability
Posted Date: 2003-07-30T04:00Z

44784
Federal
Register
/
Vol.
68,
No.
146
/
Wednesday,
July
30,
2003
/
Notices
contact,
or
inhalation,
AgriVir,
LLC
concludes
that
there
is
a
reasonable
certainty
that
no
harm
to
infants
and
children
will
result
from
dietary
exposure
to
residues
which
could
occur
as
a
result
of
approval
of
this
petition.
3.
Sensitive
individuals.
Since
the
available
information
reliably
supports
that
IMMGV
will
not
produce
adverse
effects
in
humans
of
any
age
as
a
result
of
exposure
by
ingestion,
dermal
contact,
or
inhalation,
and
indeed
that
IMMGV
appears
to
be
biologically
inactive
in
other
than
its
natural
host,
AgriVir,
LLC
concludes
that
there
is
a
reasonable
certainty
that
no
harm
to
sensitive
persons
will
result
from
dietary
exposure
to
residues
which
could
occur
as
a
result
of
approval
of
this
petition.

G.
International
Tolerances
There
are
no
Codex
maximum
residue
levels
established
for
residues
of
IMMGV.
IMMGV
containing
products
are
presently
not
registered
for
pest
control
outside
of
the
U.
S.

[
FR
Doc.
03
 
19354
Filed
7
 
29
 
03;
8:
45
am]

BILLING
CODE
6560
 
50
 
S
ENVIRONMENTAL
PROTECTION
AGENCY
[
FRL
 
7537
 
7]

Framework
for
Application
of
the
Toxicity
Equivalence
Methodology
for
Polychlorinated
Dioxins,
Furans,
and
Biphenyls
in
Ecological
Risk
Assessment
(
External
Review
Draft);
Notice
of
Availability
AGENCY:
Environmental
Protection
Agency.
ACTION:
Notice
of
availability
and
opportunity
for
public
comment.

SUMMARY:
The
U.
S.
Environmental
Protection
Agency
(
EPA)
is
announcing
a
60­
day
public
comment
period
for
the
draft
document
titled
Framework
for
Application
of
the
Toxicity
Equivalence
Methodology
for
Polychlorinated
Dioxins,
Furans,
and
Biphenyls
in
Ecological
Risk
Assessment.
The
document
is
intended
to
describe
a
methodology
for
assessing
ecological
risks
associated
with
complex
mixtures
of
dioxins,
furans,
and
dioxin­
like
PCBs
in
the
environment.
EPA
will
consider
the
public
comments
in
revising
the
document.

DATES:
Comments
must
be
received
by
September
29,
2003.
ADDRESSES:
The
draft
is
available
via
the
Internet
at
http://
cfpub.
epa.
gov/
ncea/
raf/
recordisplay.
cfm?
deid=
55669.
Comments
may
be
submitted
electronically,
by
mail,
or
in
person,
as
described
in
the
instructions
under
Supplementary
Information.
Comments
may
be
viewed
at
EPA
Dockets
at
http:/
/
www.
epa.
gov/
edocket
(
under
Docket
ID
No.
ORD
 
2003
 
0002).
FOR
FURTHER
INFORMATION
CONTACT:
Marilyn
Brower,
U.
S.
EPA,
ORD
National
Center
for
Environmental
Assessment,
Risk
Assessment
Forum
Staff
(
8601D),
1200
Pennsylvania
Ave.
NW.,
Washington,
DC
20460;
telephone:
202
 
564
 
3363;
fax:
202
 
565
 
0062;
email
brower.
marilyn@
epa.
gov.
SUPPLEMENTARY
INFORMATION:

I.
Submission
of
Comments
You
may
submit
comments
electronically,
by
mail,
or
through
hand
delivery/
courier.
To
ensure
proper
receipt
by
EPA,
identify
the
appropriate
docket
identification
number
(
ORD
 
2003
 
0002)
in
the
subject
line
on
the
first
page
of
your
comment.
Please
note
that
all
comments
received
in
response
to
this
notice
will
be
placed
in
a
public
record.
For
that
reason,
comments
should
not
contain
personal
information
(
such
as
medical
data
or
home
address),
Confidential
Business
Information,
or
information
protected
by
copyright.

A.
Electronically
to
EPA
Dockets
Your
use
of
EPA's
electronic
public
docket
(
EPA
Dockets)
to
submit
comments
is
EPA's
preferred
method
for
receiving
comments.
Go
directly
to
EPA
Dockets
at
http://
www.
epa.
gov/
edocket
and
follow
the
online
instructions
for
submitting
comments.
Once
in
the
system,
select
``
search,''
and
then
key
in
Docket
ID
No.
ORD
 
2003
 
0002.
The
system
is
an
``
anonymous
access''
system,
which
means
EPA
will
not
know
your
identity,
e­
mail
address,
or
other
contact
information
unless
you
provide
it.
EPA
recommends
that
you
include
your
name
and
contact
information
in
the
body
of
your
comment
to
ensure
that
you
can
be
identified
as
the
submitter
of
the
comment
and
to
allow
EPA
to
contact
you
in
case
EPA
cannot
read
your
comment
due
to
technical
difficulties
or
needs
further
information
on
the
substance
of
your
comment.

B.
By
Mail
Comments
may
be
sent
to:
Office
of
Environmental
Information
Docket,
Environmental
Protection
Agency,
Mailcode:
28220T,
1200
Pennsylvania
Ave.
NW,
Washington,
DC
20460,
Attention
Docket
ID
No.
ORD
 
2003
 
0002.

C.
By
Hand
Delivery
or
Courier
Deliver
your
comments
to:
Office
of
Environmental
Information
Docket,
EPA
West,
Room
B102,
1301
Constitution
Ave.
NW,
Washington,
DC,
Attention
Docket
ID
No.
ORD
 
2003
 
0002.
Such
deliveries
are
only
accepted
during
the
Docket's
normal
hours
of
operation
from
8:
30
a.
m.
to
4:
30
p.
m.,
Monday
through
Friday,
excluding
legal
holidays.
The
telephone
number
for
the
docket
is
202
 
566
 
1752.

II.
Background
Polychlorinated
dioxins
(
PCDDs),
furans
(
PCDFs),
and
biphenyls
(
PCBs)
commonly
occur
as
complex
mixtures
in
the
environment.
For
more
than
a
decade,
EPA
and
other
organizations
have
estimated
the
combined
risks
that
such
mixtures
pose
to
human
health
using
a
method
known
as
the
toxicity
equivalence
methodology.
The
methodology
is
based
on
findings
that
certain
PCDDs,
PCDFs,
and
PCBs
share
a
common
mechanism
of
action
for
their
effects
but
differ
in
potency.
The
methodology
uses
potency
factors
(
such
as
Toxicity
Equivalence
Factors,
or
TEFs)
assigned
to
each
chemical
in
the
mixture
as
a
way
of
integrating
the
risks
from
the
entire
mixture.
Application
in
ecological
risk
assessments
has
proceeded
more
slowly
than
in
human
health
risk
assessment,
in
part
because
of
the
variety
of
species
from
different
taxonomic
classes
(
e.
g.,
fish,
birds,
and
mammals)
to
be
considered.
As
both
data
and
experience
with
the
methodology
have
accumulated,
however,
experts
have
concluded
that
the
toxicity
equivalence
methodology
can
strengthen
assessments
of
ecological
risks.
At
a
World
Health
Organization
consultation
in
1997,
international
consensus
TEFs
for
PCDDs,
PCDFs,
and
PCBs
were
reviewed
and
the
toxicity
equivalence
methodology
expanded
to
include
class­
specific
TEFs
for
mammals,
birds
and
fish.
In
1998,
EPA
and
the
U.
S.
Department
of
Interior
sponsored
a
workshop
that
recommended
the
development
of
further
guidance
on
application
of
the
toxicity
equivalence
methodology.
This
draft
framework
has
been
developed
in
direct
response
to
that
workshop
recommendation
by
a
technical
panel
under
EPA's
Risk
Assessment
Forum.
Organized
in
accordance
with
EPA's
Guidelines
for
Ecological
Risk
Assessment
(
63
FR
26846),
this
framework
is
intended
to
assist
EPA
scientists
in
using
the
methodology,
as
well
as
to
inform
EPA
decision
makers,
other
agencies,
and
the
public
about
this
methodology.
It
provides
ecological
risk
assessors
with
an
understanding
of
the
uncertainties
associated
with
the
application
of
the
methodology
in
general
and
with
situation­
specific
decisions
made
in
applying
the
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44785
Federal
Register
/
Vol.
68,
No.
146
/
Wednesday,
July
30,
2003
/
Notices
methodology
within
their
risk
assessments.
The
draft
framework
also
discusses
several
potential
advantages
of
the
toxicity
equivalence
methodology
compared
with
alternative
methods
for
estimating
risks
from
mixtures
of
dioxin­
like
chemicals.
The
document
is
undergoing
peer
review
concurrent
with
the
public
comment
period
described
in
this
notice.
This
framework
is
not
a
regulation
nor
is
it
intended
to
substitute
for
federal
regulations.
It
does
not
establish
any
substantive
``
rules''
under
the
Administrative
Procedure
Act
or
any
other
law
and
will
have
no
binding
effect
on
EPA
or
any
regulated
entity.

Dated:
July
23,
2003.
Peter
W.
Preuss,
Director,
National
Center
for
Environmental
Assessment.
[
FR
Doc.
03
 
19351
Filed
7
 
29
 
03;
8:
45
am]

BILLING
CODE
6560
 
50
 
P
ENVIRONMENTAL
PROTECTION
AGENCY
[
FRC
 
7537
 
9]

Lexington
County
Landfill
Superfund
Site;
Notice
of
Proposed
Settlement
AGENCY:
Environmental
Protection
Agency.
ACTION:
Notice
of
proposed
settlement.

SUMMARY:
The
United
States
Environmental
Protection
Agency
is
proposing
to
enter
into
an
Administrative
Agreement
for
recovery
of
Future
Response
Costs
pursuant
to
section
122(
h)
(
1)
of
the
Comprehensive
Environmental
Response,
Compensation
and
Liability
Act
of
the
1980
(
CERCLA),
as
amended
regarding
the
Lexington
County
Landfill
Superfund
Site
located
in
Cayce,
Lexington
County,
South
Carolina.
This
Agreement
is
made
and
entered
into
by
EPA
and
by
Lexington
County,
South
Carolina
(``
Setting
Parties'').
EPA
will
consider
Public
comments
on
the
proposed
settlement
until
August
29,
2003.
EPA
may
withdraw
from
or
modify
the
proposed
settlement
should
such
comments
disclose
fact
or
considerations
which
indicate
the
proposed
settlement
is
appropriate,
improper,
or
inadequate.
Copies
of
the
proposed
settlement
are
available
from:
Ms.
Paula
V.
Batchelor,
U.
S.
EPA,
Region
4,
Sam
Nunn
Atlanta
Federal
Center,
Waste
Management
Division,
61
Forsyth
Street,
SW.,
Atlanta,
Georgia
30303,
(
404)
562
 
8887.
Written
comments
may
be
submitted
to
Ms.
Batchelor
within
thirty
(
30)
calendar
days
of
the
date
of
this
publication.

Dated:
July
14,
2003.
Archie
Lee,
Chief,
CERCLA
Program
Services
Branch,
Waste
Management
Division.
[
FR
Doc.
03
 
19350
Filed
7
 
29
 
03;
8:
45
am]

BILLING
CODE
6560
 
50
 
P
ENVIRONMENTAL
PROTECTION
AGENCY
[
FRL
 
7537
 
3]

Proposed
Agreement
Pursuant
to
Section
122(
h)(
1)
of
the
Comprehensive
Environmental
Response,
Compensation,
and
Liability
Act
(
CERCLA)
for
the
Sybill
Used
Oil
Processing
Plant
Site
in
Detroit,
MI
AGENCY:
Environmental
Protection
Agency
(``
EPA'').
ACTION:
Notice
and
request
for
public
comment
on
proposed
CERCLA
122(
h)(
1)
agreement
with
General
Motors
Corporation
(
GM),
Ford
Motor
Company,
Detroit
Diesel
Corporation,
Rouge
Steel
Company,
Sybill,
Inc.
and
the
Chapter
7
Bankruptcy
Trustee
for
V.
C.
Madias
addressing
contamination
at
the
Sybill
used
oil
processing
plant
in
Detroit,
Michigan.

SUMMARY:
In
accordance
with
section
122(
i)(
1)
of
CERCLA,
notification
is
hereby
given
of
a
proposed
administrative
settlement
agreement
concerning
the
Sybill
used
oil
processing
plant
at
111
Military
Street
in
Detroit,
Wayne
County,
Michigan
(
the
``
Site'').
EPA
proposes
to
enter
into
this
agreement
under
the
authority
of
sections
122(
h)
and
107
of
CERCLA.
The
proposed
agreement
has
been
executed
by
GM,
Ford
Motor
Company,
Detroit
Diesel
Corporation,
Rouge
Steel
Company,
Sybill,
Inc.
and
the
Chapter
7
Bankruptcy
Trustee
for
V.
C.
Madias
(
the
``
Settling
Parties'').
Under
the
proposed
agreement,
the
Settling
Parties
will
implement
a
removal
action
to
address
waste
oil
contamination
at
the
used
oil
processing
facility
formerly
owned
and
operated
by
Sybill,
Inc.
and
located
in
Detroit,
Michigan.
Also,
the
Settling
Parties
will
pay
to
the
Hazardous
Substances
Superfund
all
of
the
Agency's
future
oversight
costs
to
be
incurred
in
overseeing
the
work
under
the
agreement.
In
addition,
under
this
agreement,
EPA
waives
all
of
its
past
response
costs
incurred
at
the
Sybill
Site
($
56,000).
EPA
incurred
these
past
response
costs
mitigating
an
imminent
and
substantial
endangerment
to
human
health
or
the
environment
present
or
threatened
by
hazardous
substances
present
at
the
Site.
For
thirty
days
following
the
date
of
publication
of
this
notice,
the
EPA
will
receive
written
comments
relating
to
this
proposed
agreement.
EPA
will
consider
all
comments
received
and
may
decide
not
to
enter
this
proposed
agreement
if
comments
disclose
facts
or
considerations
which
indicate
that
the
proposed
agreement
is
inappropriate,
improper
or
inadequate.
DATES:
Comments
on
the
proposed
agreement
must
be
received
by
EPA
on
or
before
August
29,
2003.
ADDRESSES:
Comments
should
be
addressed
to
the
Docket
Clerk,
U.
S.
Environmental
Protection
Agency,
Region
5,
77
West
Jackson
Boulevard,
Chicago,
Illinois
60604
 
3590,
and
should
refer
to:
In
the
Matter
of
Sybill,
Inc.,
EPA
Docket
No.
V­
W
 
03­
C
 
746.

FOR
FURTHER
INFORMATION
CONTACT:
Thomas
J.
Martin,
U.
S.
Environmental
Protection
Agency,
Office
of
Regional
Counsel,
C
 
14J,
77
West
Jackson
Boulevard,
Chicago,
Illinois
60604
 
3590,
(
312)
886
 
4273.
A
copy
of
the
proposed
administrative
settlement
agreement
may
be
obtained
in
person
or
by
mail
from
the
EPA's
Region
5
Office
of
Regional
Counsel,
77
West
Jackson
Boulevard,
Chicago,
Illinois
60604
 
3590.
Additional
background
information
relating
to
the
settlement
is
available
for
review
at
the
EPA's
Region
5
Office
of
Regional
Counsel.

Authority:
The
Comprehensive
Environmental
Response,
Compensation,
and
Liability
Act,
as
amended,
42
U.
S.
C.
9601
 
9675.

William
E.
Muno,
Director,
Superfund
Division,
Region
5.
[
FR
Doc.
03
 
19284
Filed
7
 
29
 
03;
8:
45
am]

BILLING
CODE
6560
 
50
 
P
FEDERAL
COMMUNICATIONS
COMMISSION
[
Report
No.
AUC
 
03
 
51
 
B
(
Auction
No.
51);
DA
03
 
1994]

Auction
of
Regional
Narrowband
PCS
Licenses
Scheduled
for
September
24,
2003;
Notice
and
Filing
Requirements,
Minimum
Opening
Bids,
Upfront
Payments,
Package
Bidding
and
Other
Auction
Procedures
AGENCY:
Federal
Communications
Commission.
ACTION:
Notice.

SUMMARY:
This
document
announces
the
procedures
and
minimum
opening
bids
for
the
upcoming
auction
of
six
regional
narrowband
Personal
Communications
Services
(``
narrowband
PCS'')
licenses
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