Document ID: EPA-HQ-OPP-2008-0713-0006
Agency: epa
Document Type: Supporting & Related Material
Title: 
Posted Date: 2009-10-07T04:00Z

SEQ CHAPTER \h \r 1 

UNITED STATES ENVIRONMENTAL PROTECTION AGENCY

WASHINGTON, D.C.  20460

OFFICE OF              

PREVENTION, PESTICIDES

AND TOXIC SUBSTANCES 

MEMORANDUM

DATE:  	04/01/2009  

SUBJECT:	Pyraclostrobin. Acute and Chronic Aggregate Dietary (Food and
Drinking Water) Exposure and Risk Assessments to Support New Use on 
Sorghum Grain (PP#8F7385); Increase of Tolerance for the Stone Fruit
Crop Group 12 to satisfy European Union (EU) import requirement
(PP#8F7390), and Establishment of a Permanent import Tolerance for
Coffee (PP#8E7394). 

 

PC Code:  099100	DP Barcode:   359194

Decision No.: 397102	Registration No.: 7969-186, 7969-266

Petition No.: 8F7385, 8F7390, 8E7394	Regulatory Action: Section 3
Registration

Risk Assessment Type: Single chemical	Case No.: None

TXR No.: None	CAS No.: 175013-18-0

MRID No.: None	40 CFR:   180.582

REVIEWER:	Meheret Negussie, Chemist

Risk Assessment Branch III

Health Effects Division (7509P)

THROUGH:	Toiya, Goodlow, Chemist

Thomas, Bloem, Chemist

Dietary Exposure Science Advisory Council (DESAC)

Health Effects Division (7509P)

		

TO:		Barry O’Keefe, Risk Assessor

		Risk Assessment Branch III

		Health Effects Division (7509P)

		Tony Kish, RM# 22

		Fungicide Branch

		Registration Division (7505P)

Executive Summary

	

odel (DEEM-FCID™, Version 2.03), which uses food consumption data from
the U.S. Department of Agriculture’s Continuing Surveys of Food
Intakes by Individuals (CSFII) from 1994-1996 and 1998. The analyses
were performed as part of the following registration actions: (1) to
support BASF requests for tolerances for new uses in/on sorghum grain;
(2) to support a petition for increase of tolerances in the stone fruit
crop group 12 to satisfy EU import requirement; (3) petition to
establish permanent tolerance for imported green coffee beans; and (4)
to include drinking water estimates reflecting the new uses. 

   

Acute Dietary (Food and Drinking Water) Exposure Results and
Characterization

A slightly refined acute dietary exposure assessment was performed for
pyraclostrobin. The analysis used tolerance level residues or highest
field trial residues, 100% crop treated, and empirical processing
factors. Experimentally derived processing factors were used for fruit
juices, tomato and wheat commodities.  For all other processed
commodities, DEEM default processing factors were assumed. Estimated
drinking water concentrations (EDWCs) were also used. The estimated
acute drinking water concentration for pyraclostrobin (35.6 ppb) was
calculated based on a maximum application rate of 3.0 lb ai/A/season
(turf use rate).

The results of the acute dietary analysis for food alone and food and
drinking water indicate that acute dietary risks do not exceed the
Agency’s level of concern (< 100% of the aPAD) for the U.S. population
and all subgroups.  Combined dietary exposure from food and drinking
water at the 95th percentile of exposure is estimated to be 0.044629
mg/kg/day (0.043798 food alone) for the U.S. population, which is
equivalent to 1.5% of the acute Population Adjusted Dose (aPAD).  The
population subgroup with the highest estimated acute dietary exposure to
pyraclostrobin is females 13-49 years, with an estimated exposure at the
95th percentile of 0.040558 mg/kg/day (0.039679 food alone), equivalent
to 81% (79% food alone) of the aPAD.

Chronic Dietary (Food and Drinking Water) Exposure Results and
Characterization

A refined chronic dietary analysis was conducted for this assessment in
order to make room for exposure resulting from residential uses in the
aggregate assessment.  The chronic dietary analysis included tolerance
level or average field trial residues, average percent crop treated
estimate when available and empirical processing factors.  Screening
level estimates of agricultural uses of pyraclostrobin was provided by
the Biological & Economic Analysis Division (BEAD).  Experimentally
derived processing factors were used for fruit juices, tomato and wheat
commodities.  For all other processed commodities, DEEM default
processing factors were assumed.  The estimated acute drinking water
concentration for pyraclostrobin (2.3 ppb; 1 in 10 year annual mean) was
calculated based on a maximum application rate of 3.0 lb ai/A/season
(turf use rate).

 The results of the refined chronic dietary analysis which represents
for food alone and food and drinking water are below the Agency’s
level of concern for all population subgroups. The dietary exposure for
food and water is estimated at 0.002466 mg/kg/day (0.002417 mg/kg/day
for food alone) for the general U.S. population , 7.3%, of the chronic
Population Adjusted Dose (cPAD; 7.1% cPAD food alone) and 0.008032
mg/kg/day (24%, of the cPAD; 0.007960 mg/kg/day, 23% of the cPAD- food
alone) for children 1-2 yrs, the population subgroup with the highest
estimated chronic dietary exposure to pyraclostrobin.

Cancer Dietary Exposure Results and Characterization

Cancer Assessment Review Committee (CARC) recently concluded that the
chemical is “not likely to be carcinogenic to humans”, so it was not
conducted. 

I.	Introduction

Dietary risk assessment incorporates both exposure and toxicity of a
given pesticide.  For acute and chronic assessments, the risk is
expressed as a percentage of a maximum acceptable dose (i.e., the dose
which HED has concluded will result in no unreasonable adverse health
effects).  This dose is referred to as the population adjusted dose
(PAD).  The PAD is equivalent to the reference dose point of departure
(POD, NOAEL, LOAEL) divided by the required uncertainty and safety
factors.

For acute and non-cancer chronic exposures, HED is concerned when
estimated dietary risk exceeds 100% of the PAD.  HED is generally
concerned when estimated cancer risk exceeds one in one million. 
References which discuss the acute and chronic risk assessments in more
detail are available on the EPA/pesticides web site:  “Available
Information on Assessing Exposure from Pesticides, A User’s Guide,”
6/21/2000, web link:      HYPERLINK
"http://www.epa.gov/fedrgstr/EPA-PEST/2000/July/Day-12/6061.pdf" 
http://www.epa.gov/fedrgstr/EPA-PEST/2000/July/Day-12/6061.pdf  ; or see
SOP 99.6 (8/20/99).

The most recent dietary risk assessment for pyraclostrobin was conducted
by S. Piper (2/11/2008, DP # 348308).  This dietary assessment is an
update to the 2008 pyraclostrobin dietary assessment to include the
proposed new uses on sorghum grain, coffee and increase tolerance for
stone fruit crop group 12.

II.	Residue Information

Pyraclostrobin belongs to the strobilurin class of fungicides. 
Strobilurins are synthetic analogs of a natural antifungal substance
which inhibits spore germination, mycelial growth, and sporulation of
the fungus on the leaf surface.  Pyraclostrobin tolerances have been
established in 40 CFR §180.582.  Tolerances for plant commodities are
listed in 40 CFR §180.582 (a)(1) in terms of the combined residues of
the fungicide pyraclostrobin (carbamic acid,
[2-[[[1-(4-chlorophenyl)-1H- pyrazol-3-yl]oxy]methyl]phenyl]methoxy-,
methyl ester) and its desmethoxy metabolite, methyl
2-[[[1-(4-chlorophenyl)-1H-pyrazol-3-yl]oxy]methyl]phenyl carbamate,
expressed as parent compound. 

HED Metabolism Assessment Review Committee (MARC memo of 10/9/01, DP#
278044, L. Cheng) determined that for purposes of tolerance and dietary
risk assessments, the residues of concern in plant and rotational crop
commodities include pyraclostrobin and the desmethoxy metabolite.   The
residues of concern in livestock commodities include pyraclostrobin and
its metabolites convertible to 1-(4-chlorophenyl)-1H-pyrazol-3-ol and
1-(4-chloro-2-hydroxyphenyl)-1H-pyrazol-3-ol.

The potential for secondary transfer of pyraclostrobin residues of
concern in meat, milk, poultry, and eggs exists because there are
several livestock feedstuffs (sorghum forage, sorghum grain, and sorghum
stover) that are associated with the proposed uses in the current
petition (PP#8F7385).  The calculated dietary burdens of pyraclostrobin
are 4.9 ppm for beef, 9.5 ppm for dairy cattle, 0.95 ppm for poultry,
and 0.55 ppm for swine.  Based on these dietary exposure levels and the
residue data from the ruminant feeding study, the existing
pyraclostrobin tolerances for milk (0.1 ppm), meat (0.1 ppm), fat (0.1
ppm), meat byproducts except liver (0.2 ppm), and liver (1.5 ppm) of
cattle, goats, hogs, horses, and sheep are adequate to support the
proposed uses.  Tolerances for eggs and poultry are not needed based on
data from the poultry feeding and metabolism studies [Category
180.6(a)(3)].  

BASF requests the establishment of tolerances for pyraclostrobin in/on
sorghum grain,   and in/on coffee.  Also, BASF requests an increase of
tolerance for pyraclostrobin in/on stone fruit crop group 12. The
current EPA established tolerance for total residues of pyraclostrobin
in the fruit, stone, group 12 is 0.9 ppm. 

A summary of the proposed and recommended tolerances for the new uses
are listed in Table 1.

Table 1.	Tolerance Summary for Pyraclostrobin.

Commodity	Proposed Tolerance (ppm)	Recommended Tolerance (ppm)	Comments;
Correct Commodity Definition

Tolerances Proposed Under PP#8F7385

Sorghum, grain, grain	0.5	0.6	Sorghum, grain, grain. Tolerance
recommendations are tentative pending submission of a revised Section F.
Adequate field trial data are available.

Tolerances Proposed Under PP#8F7390

Fruit, stone, group 12	2.5	2.5	Fruit, stone, group 12. Adequate field
trial data are available. 

Tolerances Proposed Under PP#8E7394

Coffee, green bean	0.5	0.3	Coffee, green  bean. Tolerance
recommendations are tentative pending submission of a revised Section F.
Adequate field trial data are available. 

Residue Data used for Acute, Chronic, and/or Cancer Assessments:

For the acute dietary analysis, tolerance or highest field trial
residues and one hundred percent crop treated was assumed for all
commodities. 

For the refined chronic dietary analysis, average field trial residues
were calculated for certain crops (coffee, sorghum grain, stone fruits
crop group 12, apple, broccoli, celery, collard, grape, lettuce, citrus,
pepper, mustard green and tomato), which are the major dietary
contributors based on preliminary runs.  Field trial data were
translated from the representative commodities to the non-representative
commodities according to HED SOP 2000.1:”Guidance for Translation of
Field Trial Data from Representative Commodities in the Crop Group
Regulation to other Commodities in Each Crop Group/Subgroup.” 

Residue values used for acute and chronic assessments for the new uses
are listed in Table 2.

Table 2.     Residue Data used for Acute and Chronic Dietary Risk
Assessments.

Commodity	Acute (Tolerance, Highest  Field Trial Residues, HR (ppm)
Chronic (Average Residues, AR (ppm)

Amaranth, leafy	HR (23.38)	AR (11.77)

Arugula	HR (23.38)	AR (11.77)

Chrysanthemum	HR (23.38)	AR (11.77)

Cress, garden	HR (23.38)	AR (11.77)

Cress, upland	HR (23.38)	AR (11.77)

Dandelion, leaves	HR (23.38)	AR (11.77)

Fennel	HR (23.38)	AR (5.02)

Parsley, leaves	HR (23.38)	AR (11.77)

Radicchio	HR (23.38)	AR (0.59)

Rhubarb	HR (23.38)	AR (5.02)

Spinach	HR (23.38)	AR (11.77)

Swiss chard	HR (23.38)	AR (5.02)

Apple	Tol (1.5)	AR (0.31)

Beans, dry	HR (0.21)	Tol (0.5)

Broccoli	Tol (5.0)	AR (1.10)

Celery	HR (10.7)	AR (5.02)

Chickpea, seed	HR (0.34)	HR (0.34)

Collards	Tol (16.0)	AR (5.74)

Grape	Tol (2.0)	AR (0.768)

Guar, seed	HR (0.34)	Tol (0.5)

Lettuce, head	HR (14.4)	AR (0.59)

Lettuce, leaf	HR (20.1)	AR (7.68)

Mustard greens	Tol (16.0)	AR (5.74)

Orange	Tol (2.0)	AR (0.3)

Pea, dry	HR (0.1)	Tol (0.5)

Tomato	Tol (1.4)	AR (0.158)

Apricot 	Tol (2.5)	AR (0.602)

Cherry (sweet & sour)	Tol (2.5)	AR (0.846)

Nectarine	Tol (2.5)	AR (0.602)

Peach	Tol (2.5)	AR (0.602)

Plum 	Tol (2.5)	AR (0.198)

Coffee	Tol (0.3)	AR (0.064)

Sorghum, grain	Tol (0.6)	AR (0.09)

Experimentally derived processing factors for several commodities were
applied (summarized in Table 3).  For all other processed commodities,
DEEM (ver. 7.81) default processing factors were assumed. 

 

Table 3.     Processing Factors for Pyraclostrobin Dietary Risk
Assessment.

Commodity	PF

Apple, juice	0.2

Apple, juice - babyfood	0.2

Beet, sugar	0.4

Beet, sugar - babyfood	0.4

Beet, sugar, molasses	0.4

Beet, sugar, molasses - babyfood	0.4

Flaxseed, oil	1.2

Grape, juice	0.01

Grape, juice - babyfood	0.01

Grapefruit, juice	0.02

Grape - raisins	1.0

Lemon, juice	0.02

Lemon, juice-babyfood	0.02

Lime, juice	0.02

Lime, juice-babyfood	0.02

Orange, juice	0.02

Orange, juice-babyfood	0.02

Pineapples - dried	1.0

Pineapples - juice	1.0

Plums – prunes dried	1.3

Plums - prunes dried - babyfood	1.3

Potato, dry (granules/ flakes)	6.5

Potato, dry (granules/ flakes) - babyfood	6.5

Potato, flour	6.5

Potato, flour - babyfood	6.5

Tangerine, juice	0.02

Tomato, paste	2.1

Tomato, puree	0.55

Wheat (Triticale), flour	0.7

Wheat (Triticale), flour - babyfood	0.7

Wheat , germ	0.85

BEAD has provided updated percent crop treated information for
pyraclostrobin (A. Grube, 03/17/09).  For the chronic analyses, the
weighted average %CT was incorporated, which is listed as Adjustment
Factor 2 in the DEEM-FCID R98 file. One hundred percent crop treated was
assumed for commodities with no % CT. 

 Drinking Water Data

The drinking water residues used in the dietary risk assessment were
provided by the Environmental Fate and Effects Division (DP#s 336190,
340588, and 342584, 09/06/2007) and incorporated directly into this
dietary assessment.  Water residues were incorporated in the DEEM-FCID
into the food categories “water, direct, all sources” and “water,
indirect, all sources.”

The estimated drinking water concentrations (EDWCs) for pyraclostrobin
were calculated for ground and surface drinking water using the Tier II
(PRZM/EXAMS) surface water modeling and Tier I (SCI-GROW) groundwater
modeling based on the sorghum use pattern (R. Miller, DP# 356965,
12/17/2008).   However, the EDWCs for sorghum are significantly lower
than the exposures calculated in September 2007 based on the existing
pyraclostrobin use on turf; therefore, the estimated drinking water
concentrations will not change with the new proposed uses and the EDWCs
for turf were incorporated. 

										

The September 6, 2007 pyraclostrobin Drinking Water Exposure Assessment
was based on

 the use of Insignia (20% ai) on turf due to its highest total
application rate of 3.0 lb ai/ac 

resulting from 5 applications of 0.6 lb ai/A.  Table 4 provides a
summary of the estimated concentrations of pyraclostrobin in surface
water.  In the acute analysis, the 1-in-10 year 

peak surface water value of 35.6 ppb was used and in the chronic
analysis the surface water

value of 2.3 ppb was used. The models and their descriptions are
available at the EPA 

internet site:   HYPERLINK "http://www.epa.gov/oppefed1/models/water/" 
http://www.epa.gov/oppefed1/models/water/ . 

g/L)

	1-in-10 year Annual Peak (Acute)	1-in-10 year Annual Mean (Chronic)	30
year annual mean

(Cancer)

NJ Nursery (no irrigation)	35.6	2.3	1.5

IV.	DEEM-FCID™ Program and Consumption Information

Pyraclostrobin acute and chronic dietary exposure assessments were
conducted using the Dietary Exposure Evaluation Model software with the
Food Commodity Intake Database (DEEM-FCID™, Version 2.03), which
incorporates consumption data from USDA’s Continuing Surveys of Food
Intakes by Individuals (CSFII), 1994-1996 and 1998.  The 1994-96, 98
data are based on the reported consumption of more than 20,000
individuals over two non-consecutive survey days.  Foods “as
consumed” (e.g., apple pie) are linked to EPA-defined food commodities
(e.g. apples, peeled fruit - cooked; fresh or N/S; baked; or wheat flour
- cooked; fresh or N/S, baked) using publicly available recipe
translation files developed jointly by USDA/ARS and EPA.  For chronic
exposure assessment, consumption data are averaged for the entire U.S.
population and within population subgroups, but for acute exposure
assessment are retained as individual consumption events.  Based on
analysis of the 1994-96, 98 CSFII consumption data, which took into
account dietary patterns and survey respondents, HED concluded that it
is most appropriate to report risk for the following population
subgroups: the general U.S. population, all infants (<1 year old),
children 1-2, children 3-5, children 6-12, youth 13-19, adults 20-49,
females 13-49, and adults 50+ years old.

For chronic dietary exposure assessment, an estimate of the residue
level in each food or food-form (e.g., orange or orange juice) on the
food commodity residue list is multiplied by the average daily
consumption estimate for that food/food form to produce a residue intake
estimate.  The resulting residue intake estimate for each food/food form
is summed with the residue intake estimates for all other food/food
forms on the commodity residue list to arrive at the total average
estimated exposure.  Exposure is expressed in mg/kg body weight/day and
as a percent of the cPAD.  This procedure is performed for each
population subgroup.

For acute exposure assessments, individual one-day food consumption data
are used on an individual-by-individual basis.  The reported consumption
amounts of each food item can be multiplied by a residue point estimate
and summed to obtain a total daily pesticide exposure for a
deterministic exposure assessment, or “matched” in multiple random
pairings with residue values and then summed in a probabilistic
assessment.  The resulting distribution of exposures is expressed as a
percentage of the aPAD on both a user (i.e., only those who reported
eating relevant commodities/food forms) and a per-capita (i.e., those
who reported eating the relevant commodities as well as those who did
not) basis.  In accordance with HED policy, per capita exposure and risk
are reported for all tiers of analysis.  However, for tiers 1 and 2, any
significant differences in user vs. per capita exposure and risk are
specifically identified and noted in the risk assessment.

V.	Toxicological Information

The toxicity endpoints pertinent for human risk assessment are
summarized in Table 5.  

Table 5. Summary of Toxicological Doses and Endpoints for Pyraclostrobin
for Use in Dietary Human Health Risk Assessments.

Exposure/

Scenario	Point of Departure	Uncertainty/

FQPA Safety Factors	RfD, PAD, Level of Concern for Risk Assessment	

Study and Toxicological Effects

Acute Dietary

(Females 13-49 years of age)	NOAEL= 5.0 mg/kg/day	UFA= 10x

UFH= 10x

FQPA SF= 1x

	Acute RfD = 0.05 mg/kg/day

aPAD = 0.05 mg/kg/day	Rabbit Prenatal Developmental Toxicity

LOAEL = 10.0 mg/kg/day based on developmental toxicity findings of
increased resorptions.

Acute Dietary (General Population, including Infants and Children)	NOAEL
= 300 mg/kg/day	UFA= 10x

UFH= 10x

FQPA SF= 1x 	Acute RfD = 3.0 mg/kg/day

aPAD = 3.0 mg/kg/day	  SEQ CHAPTER \h \r 1 Rat Acute Oral Neurotoxicity

LOAEL = 1000 mg/kg/day based on decreased body weight gain in males.

Chronic Dietary (All Populations)	NOAEL= 3.4 mg/kg/day	UFA= 10x

UFH= 10x

FQPA SF= 1x

	Chronic RfD = 0.034 mg/kg/day

cPAD = 0.034 mg/kg/day	  SEQ CHAPTER \h \r 1 Rat Oral Carcinogenicity

LOAEL = 9.2 mg/kg/day based on decreased body weight/body weight gain,
kidney tubular casts and atrophy in both sexes; increased incidence of 
liver necrosis and erosion/ulceration of the glandular- stomach and
fore-stomach in males.

Cancer (oral) 	Classification:  “Not likely to be Carcinogenic to
Humans” based on the absence of significant tumor increases in two
adequate rodent carcinogenicity studies.

Point of Departure (POD) = A data point or an estimated point that is
derived from observed dose-response data and  used to mark the beginning
of extrapolation to determine risk associated with lower environmentally
relevant human exposures.  NOAEL = no observed adverse effect level. 
LOAEL = lowest observed adverse effect level.  UF = uncertainty factor. 
UFA = extrapolation from animal to human (intraspecies).  UFH =
potential variation in sensitivity among members of the human population
(interspecies).  UFL = use of a LOAEL to extrapolate a NOAEL.  UFS = use
of a short-term study for long-term risk assessment.  UFDB = to account
for the absence of key date (i.e., lack of a critical study).  FQPA SF =
FQPA Safety Factor.  PAD = population adjusted dose (a = acute, c =
chronic).  RfD = reference dose.  MOE = margin of exposure.  

VI.	Results/Discussion

As stated above, for acute and chronic assessments, HED is concerned
when dietary risk exceeds 100% of the PAD.  The DEEM-FCID™ analyses
estimate the dietary exposure of the U.S. population and various
population subgroups.  The results reported in Table 6 and 7 are for the
general U.S. Population, all infants (<1 year old), children 1-2,
children 3-5, children 6-12, youth 13-19, females 13-49, adults 20-49,
and adults 50+ years.  

Results of Acute Dietary Exposure Analysis

The results of the acute dietary analysis for food and drinking water
indicate that acute dietary risks do not exceed the Agency’s level of
concern at the 95th percentile (< 100% of the aPAD) for the U.S.
population and all subgroups. At the 95th percentile, the U.S.
population has an exposure from food and water that results in a risk
estimate for the general U.S. population of 1.5% of the aPAD.  The most
highly exposed subpopulation is “females 13-49 years” at 81% of the
aPAD. 

 

Results of Chronic Dietary Exposure Analysis

The results of the aggregate chronic dietary analysis for food and
drinking water are below the Agency’s level of concern (<100% cPAD)
for the general U.S. population (7.3% cPAD) and all population
subgroups.  The most highly exposed population subgroup is children 1-2
yrs at 24% of the cPAD.  The results of the acute and chronic dietary
exposure analyses are reported in Table 6 below.

Table 6.     Summary of Dietary Exposure and Risk for Pyraclostrobin –
Food & Drinking Water.

Population Subgroup	Acute Dietary

(95th Percentile)	Chronic Dietary	Cancer

	Dietary Exposure (mg/kg/day)	% aPAD	Dietary Exposure

(mg/kg/day)	% cPAD	Dietary Exposure

(mg/kg/day)	Risk

General U.S. Population	0.044629	1.5	0.002466	7.3	A separate
quantitative cancer risk assessment is not required.  

All Infants (< 1 year old)	0.063464	2.1	0.003682	11

	Children 1-2 years old	0.076275	2.5	0.008032	24

	Children 3-5 years old	0.066159	2.2	0.005827	17

	Children 6-12 years old	0.047354	1.6	0.003323	9.8

	Youth 13-19 years old	0.035393	1.2	0.001908	5.6

	Adults 20-49 years old	0.039279	1.3	0.001875	5.5

	Adults 50+ years old	0.041963	1.4	0.002000	5.9

	Females 13-49 years old	0.040558	81	0.001717	5.1

	

Cancer Dietary Exposure Results and Characterization

As noted above, the HED CARC has recently revisited the cancer
classification for pyraclostrobin.  HED has reclassified pyraclostrobin
as “not likely to be carcinogenic to humans", so it was not conducted.

VIII.	Characterization of Inputs/Outputs

In the course of conducting a refined dietary exposure analysis,
decisions are made regarding the following:  the residue data used in
the analysis (e.g., field trials, monitoring data, etc.), refinements
incorporated in the analysis (such as percent crop treated and
processing factors), and a variety of other issues which may be
chemical- or crop-specific.  

The acute and chronic dietary risk assessments are considered only
minimally refined.

For this assessment, tolerance level residues and field trial residue
data were incorporated in the dietary analyses.  The use of field trial
data in the assessment is unlikely to underestimate actual exposure
because field trial data reflects conservative pesticide residues at the
minimum pre-harvest interval and the maximum application rate permitted
on the proposed or existing labels.

One hundred percent crop treated was assumed for the acute analysis. 
The chronic assessment utilized average %CT estimates when available. 
Further refinements could have been carried out if additional %CT
estimates were used.     

A limited number of experimentally derived processing factors were used
to refine the acute and chronic analyses.  Default DEEM processing
factors were incorporated for all other processed commodities.  The
inclusion of additional empirical processing factors could also refine
the dietary assessment.

Estimated drinking water concentrations for surface water were also
incorporated. The contribution of residues in drinking water to the
dietary risk is minimal.  

IX.  	Conclusions

Dietary risks for pyraclostrobin are below HED’s level of concern for
dietary exposure and risk.  Females 13-49 years old are the most highly
exposed population subgroup for acute exposure, with risks estimates at
81% of the aPAD at the 95th percentile of exposure.  Children 1-2 years
old are the most highly exposed population subgroup for chronic
exposure, with risks estimates at 24% of the cPAD. Risks were lower for
all other population subgroups, including the general U.S. population. 
The acute and chronic dietary exposure assessments support the new uses
and amendments proposed for pyraclostrobin.

  

X.	List of Attachments

Attachment 1.  Pyraclostrobin Acute Dietary Analysis Input File - Food &
Water. 

Attachment 2.  Pyraclostrobin Acute Dietary Analysis Results - Food
alone.

Attachment 3.  Pyraclostrobin Acute Dietary Analysis Results - Food &
Water.

Attachment 4.  Pyraclostrobin Refined Chronic Dietary Analysis Input
File - Food & Water.

Attachment 5.  Pyraclostrobin Chronic Dietary Analysis Results - Food
alone.

Attachment 6.  Pyraclostrobin Chronic Dietary Analysis Results - Food &
Water.

Attachment 7.  Pyraclostrobin Screening Level Usage Analysis (SLUA).

Attachment 1.  Pyraclostrobin Acute Dietary Analysis Input File – Food
& Water

U.S. Environmental Protection Agency                                
Ver. 2.02

DEEM-FCID Acute analysis for PYRACLOSTROBIN

Residue file name: C:\DEEMFCID\Pyraclostrobin\Pyraclostrobin_Acute.R98

Analysis Date 03-31-2009             Residue file dated:
03-31-2009/15:54:30/8

Reference dose: aRfD = 3 mg/kg bw/day  NOEL = 300 mg/kg bw/day

Comment: New use-sorghum grain, coffee and stone fruits (Food and
Drinking water)

------------------------------------------------------------------------
--------

  EPA    Crop                                   Def Res     Adj.Factors 
 Comment

  Code    Grp  Food Name                         (ppm)       #1    #2   

-------- ---- -------------------------------  ----------  ------ ------
 -------

14000030 14   Almond                             0.040000   1.000  1.000

14000031 14   Almond-babyfood                    0.040000   1.000  1.000

14000040 14   Almond, oil                        0.040000   1.000  1.000

14000041 14   Almond, oil-babyfood               0.040000   1.000  1.000

04010050 4A   Amaranth, leafy                   23.380000   1.000  1.000

11000070 11   Apple, fruit with peel             1.500000   1.000  1.000

11000080 11   Apple, peeled fruit                1.500000   1.000  1.000

11000081 11   Apple, peeled fruit-babyfood       1.500000   1.000  1.000

11000090 11   Apple, dried                       1.500000   8.000  1.000

11000091 11   Apple, dried-babyfood              1.500000   8.000  1.000

11000100 11   Apple, juice                       1.500000   0.200  1.000

11000101 11   Apple, juice-babyfood              1.500000   0.200  1.000

11000110 11   Apple, sauce                       1.500000   1.000  1.000

11000111 11   Apple, sauce-babyfood              1.500000   1.000  1.000

12000120 12   Apricot

                 110-Uncooked; Fresh or N/S; Cook Meth N/S

                                                 2.500000   1.000  1.000
 

                 211-Cooked; Fresh or N/S; Baked

                                                 2.500000   1.000  1.000
 

                 213-Cooked; Fresh or N/S; Fried

                                                 2.500000   1.000  1.000
 

                 221-Cooked; Frozen; Baked       2.500000   1.000  1.000
 

                 232-Cooked; Dried; Boiled       2.500000   1.000  1.000
 

                 240-Cooked; Canned; Cook Meth N/S

                                                 2.500000   1.000  1.000
 

12000121 12   Apricot-babyfood

                 240-Cooked; Canned; Cook Meth N/S

                                                 2.500000   1.000  1.000
 

12000130 12   Apricot, dried                     2.500000   6.000  1.000

12000140 12   Apricot, juice                     2.500000   1.000  1.000

12000141 12   Apricot, juice-babyfood            2.500000   1.000  1.000

01030150 1CD  Arrowroot, flour                   0.040000   1.000  1.000

01030151 1CD  Arrowroot, flour-babyfood          0.040000   1.000  1.000

01030170 1CD  Artichoke, Jerusalem               0.040000   1.000  1.000

04010180 4A   Arugula                           23.380000   1.000  1.000

95000200 O    Avocado                            0.600000   1.000 
1.000PP#6E7

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09020210 9B   Balsam pear                        0.500000   1.000  1.000

95000230 O    Banana                             0.040000   1.000  1.000

95000231 O    Banana-babyfood                    0.040000   1.000  1.000

95000240 O    Banana, dried                      0.040000   3.900  1.000

95000241 O    Banana, dried-babyfood             0.040000   3.900  1.000

15000250 15   Barley, pearled barley             1.400000   1.000 
1.000PP#7E7

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15000251 15   Barley, pearled barley-babyfood    1.400000   1.000 
1.000PP#7E7

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15000260 15   Barley, flour                      1.400000   1.000 
1.000PP#7E7

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15000261 15   Barley, flour-babyfood             1.400000   1.000 
1.000PP#7E7

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15000270 15   Barley, bran                       1.400000   1.000 
1.000PP#7E7

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19010280 19A  Basil, fresh leaves               25.000000   1.000 
1.000PP#6E7

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19010281 19A  Basil, fresh leaves-babyfood      25.000000   1.000 
1.000PP#6E7

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19010290 19A  Basil, dried leaves               85.000000   1.000 
1.000PP#6E7

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19010291 19A  Basil, dried leaves-babyfood      85.000000   1.000 
1.000PP#6E7

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06030300 6C   Bean, black, seed                  0.210000   1.000  1.000

06020310 6B   Bean, broad, succulent             0.500000   1.000  1.000

06030320 6C   Bean, broad, seed                  0.210000   1.000  1.000

06020330 6B   Bean, cowpea, succulent            0.500000   1.000  1.000

06030340 6C   Bean, cowpea, seed                 0.210000   1.000  1.000

06030350 6C   Bean,  great northern, seed        0.210000   1.000  1.000

06030360 6C   Bean, kidney, seed                 0.210000   1.000  1.000

06020370 6B   Bean, lima, succulent              0.500000   1.000  1.000

06030380 6C   Bean, lima, seed                   0.210000   1.000  1.000

06030390 6C   Bean, mung, seed                   0.210000   1.000  1.000

06030400 6C   Bean, navy, seed                   0.210000   1.000  1.000

06030410 6C   Bean, pink, seed                   0.210000   1.000  1.000

06030420 6C   Bean, pinto, seed                  0.210000   1.000  1.000

06010430 6A   Bean, snap, succulent              0.500000   1.000  1.000

06010431 6A   Bean, snap, succulent-babyfood     0.500000   1.000  1.000

21000440 M    Beef, meat                         0.100000   1.000  1.000

21000441 M    Beef, meat-babyfood                0.100000   1.000  1.000

21000450 M    Beef, meat, dried                  0.100000   1.920  1.000

21000460 M    Beef, meat byproducts              0.200000   1.000  1.000

21000461 M    Beef, meat byproducts-babyfood     0.200000   1.000  1.000

21000470 M    Beef, fat                          0.100000   1.000  1.000

21000471 M    Beef,fat-babyfood                  0.100000   1.000  1.000

21000480 M    Beef, kidney                       0.200000   1.000  1.000

21000490 M    Beef, liver                        1.500000   1.000  1.000

21000491 M    Beef, liver-babyfood               1.500000   1.000  1.000

01010500 1AB  Beet, garden, roots                0.400000   1.000  1.000

01010501 1AB  Beet, garden, roots-babyfood       0.400000   1.000  1.000

02000510 2    Beet, garden, tops                16.000000   1.000  1.000

01010520 1A   Beet, sugar                        0.200000   0.400  1.000

01010521 1A   Beet, sugar-babyfood               0.200000   0.400  1.000

01010530 1A   Beet, sugar, molasses              0.200000   0.400  1.000

01010531 1A   Beet, sugar, molasses-babyfood     0.200000   0.400  1.000

95000540 O    Belgium endive                    11.000000   1.000  1.000

13010550 13A  Blackberry                         4.000000   1.000  1.000

13010560 13A  Blackberry, juice                  4.000000   1.000  1.000

13010561 13A  Blackberry, juice-babyfood         4.000000   1.000  1.000

13020570 13B  Blueberry                          4.000000   1.000  1.000

13020571 13B  Blueberry-babyfood                 4.000000   1.000  1.000

13010580 13A  Boysenberry                        4.000000   1.000  1.000

14000590 14   Brazil nut                         0.040000   1.000  1.000

05010610 5A   Broccoli                           5.000000   1.000  1.000

05010611 5A   Broccoli-babyfood                  5.000000   1.000  1.000

05010620 5A   Broccoli, Chinese                  5.000000   1.000  1.000

05020630 5B   Broccoli raab                     16.000000   1.000  1.000

05010640 5A   Brussels sprouts                   5.000000   1.000  1.000

01010670 1AB  Burdock                            0.400000   1.000  1.000

14000680 14   Butternut                          0.040000   1.000  1.000

05010690 5A   Cabbage                            5.000000   1.000  1.000

05020700 5B   Cabbage, Chinese, bok choy        16.000000   1.000  1.000

05010710 5A   Cabbage, Chinese, napa             5.000000   1.000  1.000

05010720 5A   Cabbage, Chinese, mustard          5.000000   1.000  1.000

95000740 O    Canistel                           0.600000   1.000 
1.000PP#6E7

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09010750 9A   Cantaloupe                         0.500000   1.000  1.000

04020760 4B   Cardoon                           23.380000   1.000  1.000

01010780 1AB  Carrot                             0.400000   1.000  1.000

01010781 1AB  Carrot-babyfood                    0.400000   1.000  1.000

01010790 1AB  Carrot, juice                      0.400000   1.000  1.000

09010800 9A   Casaba                             0.500000   1.000  1.000

14000810 14   Cashew                             0.040000   1.000  1.000

01030820 1CD  Cassava                            0.040000   1.000  1.000

01030821 1CD  Cassava-babyfood                   0.040000   1.000  1.000

05010830 5A   Cauliflower                        5.000000   1.000  1.000

01010840 1AB  Celeriac                           0.400000   1.000  1.000

04020850 4B   Celery                            10.700000   1.000  1.000

04020851 4B   Celery-babyfood                   10.700000   1.000  1.000

04020860 4B   Celery, juice                     10.700000   1.000  1.000

04020870 4B   Celtuce                           10.700000   1.000  1.000

09020880 9B   Chayote, fruit                     0.500000   1.000  1.000

12000900 12   Cherry                             2.500000   1.000  1.000

12000901 12   Cherry-babyfood                    2.500000   1.000  1.000

12000910 12   Cherry, juice                      2.500000   1.500  1.000

12000911 12   Cherry, juice-babyfood             2.500000   1.500  1.000

14000920 14   Chestnut                           0.040000   1.000  1.000

06030980 6C   Chickpea, seed                     0.340000   1.000  1.000

06030981 6C   Chickpea, seed-babyfood            0.340000   1.000  1.000

06030990 6C   Chickpea, flour                    0.340000   1.000  1.000

01011000 1AB  Chicory, roots                     0.400000   1.000  1.000

02001010 2    Chicory, tops                     16.000000   1.000  1.000

09021020 9B   Chinese waxgourd                   0.500000   1.000  1.000

19011030 19A  Chive                             25.000000   1.000 
1.000PP#6E7

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04011040 4A   Chrysanthemum, garland            23.380000   1.000  1.000

10001060 10   Citrus citron                      2.000000   1.000  1.000

10001070 10   Citrus hybrids                     2.000000   1.000  1.000

10001080 10   Citrus, oil                        9.000000   1.000  1.000

95001150 O    Coffee, roasted bean               0.300000   1.000  1.000

95001160 O    Coffee, instant                    0.300000   1.000  1.000

05021170 5B   Collards                          16.000000   1.000  1.000

19011180 19A  Coriander, leaves                 25.000000   1.000 
1.000PP#6E7

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19011181 19A  Coriander, leaves-babyfood        25.000000   1.000 
1.000PP#6E7

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15001200 15   Corn, field, flour                 0.100000   1.000  1.000

15001201 15   Corn, field, flour-babyfood        0.100000   1.000  1.000

15001210 15   Corn, field, meal                  0.100000   1.000  1.000

15001211 15   Corn, field, meal-babyfood         0.100000   1.000  1.000

15001220 15   Corn, field, bran                  0.100000   1.000  1.000

15001230 15   Corn, field, starch                0.100000   1.000  1.000

15001231 15   Corn, field, starch-babyfood       0.100000   1.000  1.000

15001240 15   Corn, field, syrup                 0.100000   1.500  1.000

15001241 15   Corn, field, syrup-babyfood        0.100000   1.500  1.000

15001250 15   Corn, field, oil                   0.200000   1.000  1.000

15001251 15   Corn, field, oil-babyfood          0.200000   1.000  1.000

15001260 15   Corn, pop                          0.100000   1.000  1.000

15001270 15   Corn, sweet                        0.040000   1.000  1.000

15001271 15   Corn, sweet-babyfood               0.040000   1.000  1.000

95001280 O    Cottonseed, oil                    0.300000   1.000 
1.000PP#6E7

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95001281 O    Cottonseed, oil-babyfood           0.300000   1.000 
1.000PP#6E7

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11001290 11   Crabapple                          1.500000   1.000  1.000

04011330 4A   Cress, garden                     23.380000   1.000  1.000

04011340 4A   Cress, upland                     23.380000   1.000  1.000

09021350 9B   Cucumber                           0.500000   1.000  1.000

13021360 13B  Currant                            4.000000   1.000  1.000

13021370 13B  Currant, dried                     4.000000   1.000  1.000

04011380 4A   Dandelion, leaves                 23.380000   1.000  1.000

01031390 1CD  Dasheen, corm                      0.040000   1.000  1.000

02001400 2    Dasheen, leaves                   16.000000   1.000  1.000

13011420 13A  Dewberry                           4.000000   1.000  1.000

19021430 19B  Dill, seed                        25.000000   1.000 
1.000PP#6E7

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19011440 19A  Dillweed                          25.000000   1.000 
1.000PP#6E7

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08001480 8    Eggplant                           1.400000   1.000  1.000

13021490 13B  Elderberry                         4.000000   1.000  1.000

04011500 4A   Endive                            23.380000   1.000  1.000

04021520 4B   Fennel, Florence                  23.380000   1.000  1.000

14001550 14   Filbert                            0.040000   1.000  1.000

14001560 14   Filbert, oil                       0.040000   1.000  1.000

20001630 20   Flaxseed, oil                      0.450000   1.200 
1.000PP#6E7

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03001640 3    Garlic                             0.900000   1.000  1.000

03001650 3    Garlic, dried                      0.900000   1.000  1.000

03001651 3    Garlic, dried-babyfood             0.900000   1.000  1.000

01031660 1CD  Ginger                             0.040000   1.000  1.000

01031661 1CD  Ginger-babyfood                    0.040000   1.000  1.000

01031670 1CD  Ginger, dried                      0.040000   1.000  1.000

01011680 1AB  Ginseng, dried                     0.400000   1.000  1.000

23001690 M    Goat, meat                         0.100000   1.000  1.000

23001700 M    Goat, meat byproducts              0.200000   1.000  1.000

23001710 M    Goat, fat                          0.100000   1.000  1.000

23001720 M    Goat, kidney                       0.200000   1.000  1.000

23001730 M    Goat, liver                        1.500000   1.000  1.000

13021740 13B  Gooseberry                         4.000000   1.000  1.000

95001750 O    Grape                              2.000000   1.000  1.000

95001760 O    Grape, juice                       2.000000   0.010  1.000

95001761 O    Grape, juice-babyfood              2.000000   0.010  1.000

95001770 O    Grape, leaves                      2.000000   1.000  1.000

95001780 O    Grape, raisin                      7.000000   1.000  1.000

95001790 O    Grape, wine and sherry             2.000000   1.000  1.000

10001800 10   Grapefruit                         2.000000   1.000  1.000

10001810 10   Grapefruit, juice                  2.000000   0.020  1.000

06031820 6C   Guar, seed                         0.340000   1.000  1.000

06031821 6C   Guar, seed-babyfood                0.340000   1.000  1.000

19011840 19A  Herbs, other                      25.000000   1.000 
1.000PP#6E7

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19011841 19A  Herbs, other-babyfood             25.000000   1.000 
1.000PP#6E7

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14001850 14   Hickory nut                        0.040000   1.000  1.000

09011870 9A   Honeydew melon                     0.500000   1.000  1.000

95001880 O    Hop                               23.000000   1.000  1.000

24001890 M    Horse, meat                        0.100000   1.000  1.000

01011900 1AB  Horseradish                        0.400000   1.000  1.000

13021910 13B  Huckleberry                        4.000000   1.000  1.000

05021940 5B   Kale                              16.000000   1.000  1.000

05011960 5A   Kohlrabi                           5.000000   1.000  1.000

10001970 10   Kumquat                            2.000000   1.000  1.000

03001980 3    Leek                               0.900000   1.000  1.000

10001990 10   Lemon                              2.000000   1.000  1.000

10002000 10   Lemon, juice                       2.000000   0.020  1.000

10002001 10   Lemon, juice-babyfood              2.000000   0.020  1.000

10002010 10   Lemon, peel                        2.000000   1.000  1.000

19012020 19A  Lemongrass                        25.000000   1.000 
1.000PP#6E7

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06032030 6C   Lentil, seed                       0.340000   1.000  1.000

04012040 4A   Lettuce, head                     14.400000   1.000  1.000

04012050 4A   Lettuce, leaf                     20.100000   1.000  1.000

10002060 10   Lime                               2.000000   1.000  1.000

10002070 10   Lime, juice                        2.000000   0.020  1.000

10002071 10   Lime, juice-babyfood               2.000000   0.020  1.000

13012080 13A  Loganberry                         4.000000   1.000  1.000

11002100 11   Loquat                             1.500000   1.000  1.000

14002130 14   Macadamia nut                      0.040000   1.000  1.000

95002150 O    Mango                              0.600000   1.000 
1.000PP#6E7

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95002151 O    Mango-babyfood                     0.600000   1.000 
1.000PP#6E7

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95002160 O    Mango, dried                       0.600000   1.000 
1.000PP#6E7

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95002170 O    Mango, juice                       0.600000   1.000 
1.000PP#6E7

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95002171 O    Mango, juice-babyfood              0.600000   1.000 
1.000PP#6E7

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19012200 19A  Marjoram                          25.000000   1.000 
1.000PP#6E7

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19012201 19A  Marjoram-babyfood                 25.000000   1.000 
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27002220 D    Milk, fat                          0.100000   1.000  1.000

27002221 D    Milk, fat - baby food/infant for   0.100000   1.000  1.000

27012230 D    Milk, nonfat solids                0.100000   1.000  1.000

27012231 D    Milk, nonfat solids-baby food/in   0.100000   1.000  1.000

27022240 D    Milk, water                        0.100000   1.000  1.000

27022241 D    Milk, water-babyfood/infant form   0.100000   1.000  1.000

27032251 D    Milk, sugar (lactose)-baby food/   0.100000   1.000  1.000

05022290 5B   Mustard greens                    16.000000   1.000  1.000

12002300 12   Nectarine                          2.500000   1.000  1.000

15002310 15   Oat, bran                          1.200000   1.000 
1.000PP#6E7

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15002320 15   Oat, flour                         1.200000   1.000 
1.000PP#6E7

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15002321 15   Oat, flour-babyfood                1.200000   1.000 
1.000PP#6E7

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15002330 15   Oat, groats/rolled oats            1.200000   1.000 
1.000PP#6E7

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15002331 15   Oat, groats/rolled oats-babyfood   1.200000   1.000 
1.000PP#6E7

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08002340 8    Okra                               1.400000   1.000  1.000

03002370 3    Onion, dry bulb                    0.900000   1.000  1.000

03002371 3    Onion, dry bulb-babyfood           0.900000   1.000  1.000

03002380 3    Onion, dry bulb, dried             0.900000   9.000  1.000

03002381 3    Onion, dry bulb, dried-babyfood    0.900000   9.000  1.000

03002390 3    Onion, green                       0.900000   1.000  1.000

10002400 10   Orange                             2.000000   1.000  1.000

10002410 10   Orange, juice                      2.000000   0.020  1.000

10002411 10   Orange, juice-babyfood             2.000000   0.020  1.000

10002420 10   Orange, peel                       2.000000   1.000  1.000

95002450 O    Papaya                             0.600000   1.000 
1.000PP#6E7

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95002451 O    Papaya-babyfood                    0.600000   1.000 
1.000PP#6E7

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95002460 O    Papaya, dried                      0.600000   1.800 
1.000PP#6E7

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95002470 O    Papaya, juice                      0.600000   1.500 
1.000PP#6E7

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04012480 4A   Parsley, leaves                   23.380000   1.000  1.000

19012490 19A  Parsley, dried leaves             85.000000   1.000 
1.000PP#6E7

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19012491 19A  Parsley, dried leaves-babyfood    85.000000   1.000 
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01012500 1AB  Parsley, turnip rooted             0.400000   1.000  1.000

01012510 1AB  Parsnip                            0.400000   1.000  1.000

01012511 1AB  Parsnip-babyfood                   0.400000   1.000  1.000

06022550 6B   Pea, succulent                     0.200000   1.000  1.000

06022551 6B   Pea, succulent-babyfood            0.200000   1.000  1.000

06032560 6C   Pea, dry                           0.100000   1.000  1.000

06032561 6C   Pea, dry-babyfood                  0.100000   1.000  1.000

06012570 6A   Pea, edible podded, succulent      0.500000   1.000  1.000

06032580 6C   Pea, pigeon, seed                  0.100000   1.000  1.000

06022590 6B   Pea, pigeon, succulent             0.200000   1.000  1.000

12002600 12   Peach                              2.500000   1.000  1.000

12002601 12   Peach-babyfood                     2.500000   1.000  1.000

12002610 12   Peach, dried                       2.500000   7.000  1.000

12002611 12   Peach, dried-babyfood              2.500000   7.000  1.000

12002620 12   Peach, juice                       2.500000   1.000  1.000

12002621 12   Peach, juice-babyfood              2.500000   1.000  1.000

95002630 O    Peanut                             0.050000   1.000  1.000

95002640 O    Peanut, butter                     0.050000   1.890  1.000

95002650 O    Peanut, oil                        0.100000   1.000  1.000

11002660 11   Pear                               1.500000   1.000  1.000

11002661 11   Pear-babyfood                      1.500000   1.000  1.000

11002670 11   Pear, dried                        1.500000   6.250  1.000

11002680 11   Pear, juice                        1.500000   1.000  1.000

11002681 11   Pear, juice-babyfood               1.500000   1.000  1.000

14002690 14   Pecan                              0.040000   1.000  1.000

08002700 8    Pepper, bell                       1.400000   1.000  1.000

08002701 8    Pepper, bell-babyfood              1.400000   1.000  1.000

08002710 8    Pepper, bell, dried                1.400000   1.000  1.000

08002711 8    Pepper, bell, dried-babyfood       1.400000   1.000  1.000

08002720 8    Pepper, nonbell                    1.400000   1.000  1.000

08002721 8    Pepper, nonbell-babyfood           1.400000   1.000  1.000

08002730 8    Pepper, nonbell, dried             1.400000   1.000  1.000

95002750 O    Peppermint                         8.000000   1.000  1.000

95002760 O    Peppermint, oil                    8.000000   1.000  1.000

14002820 14   Pistachio                          0.700000   1.000  1.000

95002830 O    Plantain                           0.040000   1.000  1.000

95002840 O    Plantain, dried                    0.040000   3.900  1.000

12002850 12   Plum                               2.500000   1.000  1.000

12002851 12   Plum-babyfood                      2.500000   1.000  1.000

12002860 12   Plum, prune, fresh                 2.500000   1.000  1.000

12002861 12   Plum, prune, fresh-babyfood        2.500000   1.000  1.000

12002870 12   Plum, prune, dried                 2.500000   1.300  1.000

12002871 12   Plum, prune, dried-babyfood        2.500000   1.300  1.000

12002880 12   Plum, prune, juice                 2.500000   1.400  1.000

12002881 12   Plum, prune, juice-babyfood        2.500000   1.400  1.000

25002900 M    Pork, meat                         0.100000   1.000  1.000

25002901 M    Pork, meat-babyfood                0.100000   1.000  1.000

25002910 M    Pork, skin                         0.100000   1.000  1.000

25002920 M    Pork, meat byproducts              0.200000   1.000  1.000

25002921 M    Pork, meat byproducts-babyfood     0.200000   1.000  1.000

25002930 M    Pork, fat                          0.100000   1.000  1.000

25002931 M    Pork, fat-babyfood                 0.100000   1.000  1.000

25002940 M    Pork, kidney                       0.200000   1.000  1.000

25002950 M    Pork, liver                        1.500000   1.000  1.000

01032960 1C   Potato, chips                      0.040000   1.000  1.000

01032970 1C   Potato, dry (granules/ flakes)     0.040000   6.500  1.000

01032971 1C   Potato, dry (granules/ flakes)-b   0.040000   6.500  1.000

01032980 1C   Potato, flour                      0.040000   6.500  1.000

01032981 1C   Potato, flour-babyfood             0.040000   6.500  1.000

01032990 1C   Potato, tuber, w/peel              0.040000   1.000  1.000

01032991 1C   Potato, tuber, w/peel-babyfood     0.040000   1.000  1.000

01033000 1C   Potato, tuber, w/o peel            0.040000   1.000  1.000

01033001 1C   Potato, tuber, w/o peel-babyfood   0.040000   1.000  1.000

10003070 10   Pummelo                            2.000000   1.000  1.000

09023080 9B   Pumpkin                            0.500000   1.000  1.000

09023090 9B   Pumpkin, seed                      0.500000   1.000  1.000

11003100 11   Quince                             1.500000   1.000  1.000

04013130 4A   Radicchio                         23.380000   1.000  1.000

01013140 1AB  Radish, roots                      0.400000   1.000  1.000

02003150 2    Radish, tops                      16.000000   1.000  1.000

01013160 1AB  Radish, Oriental, roots            0.400000   1.000  1.000

02003170 2    Radish, Oriental, tops            16.000000   1.000  1.000

05023180 5B   Rape greens                       16.000000   1.000  1.000

20003190 20   Rapeseed, oil                      0.450000   1.000 
1.000PP#6E7

          Full comment: PP#6E7105

20003191 20   Rapeseed, oil-babyfood             0.450000   1.000 
1.000PP#6E7

          Full comment: PP#6E7105

13013200 13A  Raspberry                          4.000000   1.000  1.000

13013201 13A  Raspberry-babyfood                 4.000000   1.000  1.000

13013210 13A  Raspberry, juice                   4.000000   1.000  1.000

13013211 13A  Raspberry, juice-babyfood          4.000000   1.000  1.000

04023220 4B   Rhubarb                           23.380000   1.000  1.000

01013270 1AB  Rutabaga                           0.400000   1.000  1.000

15003280 15   Rye, grain                         0.040000   1.000  1.000

15003290 15   Rye, flour                         0.040000   1.000  1.000

20003300 20   Safflower, oil                     0.450000   1.000 
1.000PP#6E7

          Full comment: PP#6E7105

20003301 20   Safflower, oil-babyfood            0.450000   1.000 
1.000PP#6E7

          Full comment: PP#6E7105

01013310 1AB  Salsify, roots                     0.400000   1.000  1.000

02003320 2    Salsify, tops                     16.000000   1.000  1.000

95003330 O    Sapote, Mamey                      0.600000   1.000 
1.000PP#6E7

          Full comment: PP#6E7165

19013340 19A  Savory                            25.000000   1.000 
1.000PP#6E7

          Full comment: PP#6E7165

95003360 O    Sesame, seed                       0.450000   1.000 
1.000PP#6E7

          Full comment: PP#6E7105

95003361 O    Sesame, seed-babyfood              0.450000   1.000 
1.000PP#6E7

          Full comment: PP#6E7105

95003370 O    Sesame, oil                        0.450000   1.000 
1.000PP#6E7

          Full comment: PP#6E7105

95003371 O    Sesame, oil-babyfood               0.450000   1.000 
1.000PP#6E7

          Full comment: PP#6E7105

03003380 3    Shallot                            0.900000   1.000  1.000

26003390 M    Sheep, meat                        0.100000   1.000  1.000

26003391 M    Sheep, meat-babyfood               0.100000   1.000  1.000

26003400 M    Sheep, meat byproducts             0.200000   1.000  1.000

26003410 M    Sheep, fat                         0.100000   1.000  1.000

26003411 M    Sheep, fat-babyfood                0.100000   1.000  1.000

26003420 M    Sheep, kidney                      0.200000   1.000  1.000

26003430 M    Sheep, liver                       1.500000   1.000  1.000

15003440 15   Sorghum, grain                     0.600000   1.000  1.000

15003450 15   Sorghum, syrup                     0.600000   1.000  1.000

06003470 6    Soybean, seed                      0.040000   1.000  1.000

06003480 6    Soybean, flour                     0.040000   1.000  1.000

06003481 6    Soybean, flour-babyfood            0.040000   1.000  1.000

06003490 6    Soybean, soy milk                  0.040000   1.000  1.000

06003491 6    Soybean, soy milk-babyfood or in   0.040000   1.000  1.000

06003500 6    Soybean, oil                       0.040000   0.800  1.000

06003501 6    Soybean, oil-babyfood              0.040000   0.800  1.000

95003520 O    Spearmint                          8.000000   1.000  1.000

95003530 O    Spearmint, oil                     8.000000   1.000  1.000

04013550 4A   Spinach                           23.380000   1.000  1.000

04013551 4A   Spinach-babyfood                  23.380000   1.000  1.000

09023560 9B   Squash, summer                     0.500000   1.000  1.000

09023561 9B   Squash, summer-babyfood            0.500000   1.000  1.000

09023570 9B   Squash, winter                     0.500000   1.000  1.000

09023571 9B   Squash, winter-babyfood            0.500000   1.000  1.000

95003590 O    Strawberry                         1.200000   1.000  1.000

95003591 O    Strawberry-babyfood                1.200000   1.000  1.000

95003600 O    Strawberry, juice                  1.200000   1.000  1.000

95003601 O    Strawberry, juice-babyfood         1.200000   1.000  1.000

95003620 O    Sugarcane, sugar                   0.020000   1.000  1.000

95003621 O    Sugarcane, sugar-babyfood          0.020000   1.000  1.000

95003630 O    Sugarcane, molasses                0.400000   1.000  1.000

95003631 O    Sugarcane, molasses-babyfood       0.400000   1.000  1.000

20003640 20   Sunflower, seed                    0.450000   1.000 
1.000PP#6E7

          Full comment: PP#6E7105

20003650 20   Sunflower, oil                     0.450000   1.000 
1.000PP#6E7

          Full comment: PP#6E7105

20003651 20   Sunflower, oil-babyfood            0.450000   1.000 
1.000PP#6E7

          Full comment: PP#6E7105

01033660 1CD  Sweet potato                       0.040000   1.000  1.000

01033661 1CD  Sweet potato-babyfood              0.040000   1.000  1.000

04023670 4B   Swiss chard                       23.380000   1.000  1.000

10003690 10   Tangerine                          2.000000   1.000  1.000

10003700 10   Tangerine, juice                   2.000000   0.020  1.000

01033710 1CD  Tanier, corm                       0.040000   1.000  1.000

08003740 8    Tomatillo                          1.400000   1.000  1.000

08003750 8    Tomato                             1.400000   1.000  1.000

08003751 8    Tomato-babyfood                    1.400000   1.000  1.000

08003760 8    Tomato, paste                      1.400000   2.100  1.000

08003761 8    Tomato, paste-babyfood             1.400000   2.100  1.000

08003770 8    Tomato, puree                      1.400000   0.550  1.000

08003771 8    Tomato, puree-babyfood             1.400000   0.550  1.000

08003780 8    Tomato, dried                      1.400000  14.300  1.000

08003781 8    Tomato, dried-babyfood             1.400000  14.300  1.000

08003790 8    Tomato, juice                      1.400000   1.500  1.000

15003810 15   Triticale, flour                   0.200000   0.700  1.000

15003811 15   Triticale, flour-babyfood          0.200000   0.700  1.000

01033870 1CD  Turmeric                           0.040000   1.000  1.000

01013880 1AB  Turnip, roots                      0.400000   1.000  1.000

05023890 5B   Turnip, greens                    16.000000   1.000  1.000

14003910 14   Walnut                             0.040000   1.000  1.000

86010000 O    Water, direct, all sources         0.035600   1.000  1.000

86020000 O    Water, indirect, all sources       0.035600   1.000  1.000

09013990 9A   Watermelon                         0.500000   1.000  1.000

09014000 9A   Watermelon, juice                  0.500000   1.000  1.000

15004010 15   Wheat, grain                       0.200000   1.000  1.000

15004011 15   Wheat, grain-babyfood              0.200000   1.000  1.000

15004020 15   Wheat, flour                       0.200000   0.700  1.000

15004021 15   Wheat, flour-babyfood              0.200000   0.700  1.000

15004030 15   Wheat, germ                        0.200000   0.850  1.000

15004040 15   Wheat, bran                        0.200000   1.000  1.000

01034060 1CD  Yam, true                          0.040000   1.000  1.000

01034070 1CD  Yam bean                           0.040000   1.000  1.000

Attachment 2.  Pyraclostrobin Acute Dietary Analysis Results – Food
alone

U.S. Environmental Protection Agency                                 
Ver. 2.02

DEEM-FCID ACUTE Analysis for PYRACLOSTROBIN                     
(1994-98 data)

Residue file: Pyraclostrobin_AcuteFood.R98        Adjustment factor #2
NOT used.

Analysis Date: 03-31-2009/16:09:53    Residue file dated:
03-31-2009/15:38:26/8

NOEL (Acute) = 300.000000 mg/kg body-wt/day

Acute Pop Adjusted Dose (aPAD) varies with population; see individual
reports

Daily totals for food and foodform consumption used.

Run Comment: "New use-sorghum grain, coffee and stone fruits (Food
alone)"

========================================================================
=======

Summary calculations (per capita):

      95th Percentile             99th Percentile             99.9th
Percentile

 Exposure  % aPAD     MOE    Exposure  % aPAD     MOE    Exposure  %
aPAD     MOE  

---------- ------- -------- ---------- ------- -------- ----------
------- --------

U.S. Population:

  0.043798    1.46    6849    0.076263    2.54    3933    0.148697   
4.96    2017  

All infants:

  0.061785    2.06    4855    0.188350    6.28    1592    0.443995  
14.80     675  

Children 1-2 yrs:

  0.074798    2.49    4010    0.140518    4.68    2134    0.486948  
16.23     616  

Children 3-5 yrs:

  0.064935    2.16    4619    0.110413    3.68    2717    0.282614   
9.42    1061  

Children 6-12 yrs:

  0.046682    1.56    6426    0.073649    2.45    4073    0.156046   
5.20    1922  

Youth 13-19 yrs:

  0.034889    1.16    8598    0.064273    2.14    4667    0.097359   
3.25    3081  

Adults 20-49 yrs:

  0.038487    1.28    7794    0.070502    2.35    4255    0.123006   
4.10    2438  

Adults 50+ yrs:

  0.040934    1.36    7328    0.071802    2.39    4178    0.126797   
4.23    2365  

Females 13-49 yrs:

  0.039679   79.36    7560    0.072975  145.95    4110    0.141270 
282.54    2123  



Attachment 3.  Pyraclostrobin Acute Dietary Analysis Results – Food &
Water

U.S. Environmental Protection Agency                                 
Ver. 2.02

DEEM-FCID ACUTE Analysis for PYRACLOSTROBIN                     
(1994-98 data)

Residue file: Pyraclostrobin_Acute.R98            Adjustment factor #2
NOT used.

Analysis Date: 03-31-2009/16:01:01    Residue file dated:
03-31-2009/15:54:30/8

NOEL (Acute) = 300.000000 mg/kg body-wt/day

Acute Pop Adjusted Dose (aPAD) varies with population; see individual
reports

Daily totals for food and foodform consumption used.

Run Comment: "New use-sorghum grain, coffee and stone fruits (Food and
Drinkin

g water)"

========================================================================
=======

Summary calculations (per capita):

      95th Percentile             99th Percentile             99.9th
Percentile

 Exposure  % aPAD     MOE    Exposure  % aPAD     MOE    Exposure  %
aPAD     MOE  

---------- ------- -------- ---------- ------- -------- ----------
------- --------

U.S. Population:

  0.044629    1.49    6722    0.077204    2.57    3885    0.152097   
5.07    1972  

All infants:

  0.063464    2.12    4727    0.193497    6.45    1550    0.448307  
14.94     669  

Children 1-2 yrs:

  0.076275    2.54    3933    0.142286    4.74    2108    0.487054  
16.24     615  

Children 3-5 yrs:

  0.066159    2.21    4534    0.112020    3.73    2678    0.284196   
9.47    1055  

Children 6-12 yrs:

  0.047354    1.58    6335    0.073465    2.45    4083    0.140059   
4.67    2141  

Youth 13-19 yrs:

  0.035393    1.18    8476    0.065472    2.18    4582    0.098390   
3.28    3049  

Adults 20-49 yrs:

  0.039279    1.31    7637    0.071111    2.37    4218    0.125166   
4.17    2396  

Adults 50+ yrs:

  0.041963    1.40    7149    0.072799    2.43    4120    0.128883   
4.30    2327  

Females 13-49 yrs:

  0.040558   81.12    7396    0.073700  147.40    4070    0.142159 
284.32    2110  

Attachment 4.  Pyraclostrobin Refined Chronic Dietary Analysis Input
File – Food & Water

U.S. Environmental Protection Agency                                
Ver. 2.00

DEEM-FCID Chronic analysis for PYRACLOSTROBIN                    
1994-98 data

Residue file: C:\DEEMFCID\Pyraclostrobin\Pyraclostrobin_ChronicSLUA.R98

                                                               Adjust.
#2 used

Analysis Date 03-31-2009             Residue file dated:
03-31-2009/15:55:39/8

Reference dose (RfD) = 0.034 mg/kg bw/day

Comment:Chronic-new use sorghum grain, coffee, stone fruits (Food and
drinking water), SLUA-PCT

------------------------------------------------------------------------
--------

Food Crop                                       Residue      
Adj.Factors      Comment

EPA Code  Grp  Food Name                          (ppm)       

                                                             #1        
#2 

-------- ---- -------------------------------   ---------- ------    
------   -------

14000030 14   Almond                             0.040000   1.000     
0.350   

14000031 14   Almond-babyfood                    0.040000   1.000     
0.350   

14000040 14   Almond, oil                        0.040000   1.000     
0.350   

14000041 14   Almond, oil-babyfood               0.040000   1.000     
0.350   

04010050 4A   Amaranth, leafy                   11.770000   1.000     
1.000   

11000070 11   Apple, fruit with peel             0.310000   1.000     
0.100   

11000080 11   Apple, peeled fruit                0.310000   1.000     
0.100   

11000081 11   Apple, peeled fruit-babyfood       0.310000   1.000     
0.100   

11000090 11   Apple, dried                       0.310000   8.000     
0.100   

11000091 11   Apple, dried-babyfood              0.310000   8.000     
0.100   

11000100 11   Apple, juice                       0.310000   0.200     
0.100   

11000101 11   Apple, juice-babyfood              0.310000   0.200     
0.100   

11000110 11   Apple, sauce                       0.310000   1.000     
0.100   

11000111 11   Apple, sauce-babyfood              0.310000   1.000     
0.100   

12000120 12   Apricot                            0.602000   1.000     
0.100   

12000121 12   Apricot-babyfood                   0.602000   1.000     
0.100   

12000130 12   Apricot, dried                     0.602000   6.000     
0.100   

12000140 12   Apricot, juice                     0.602000   1.000     
0.100   

12000141 12   Apricot, juice-babyfood            0.602000   1.000     
0.100   

01030150 1CD  Arrowroot, flour                   0.040000   1.000     
1.000   

01030151 1CD  Arrowroot, flour-babyfood          0.040000   1.000     
1.000   

01030170 1CD  Artichoke, Jerusalem               0.040000   1.000     
1.000   

04010180 4A   Arugula                           11.770000   1.000     
1.000   

95000200 O    Avocado                            0.600000   1.000     
1.000   PP#6E7

  Full comment: PP#6E7165

09020210 9B   Balsam pear                        0.500000   1.000     
1.000   

95000230 O    Banana                             0.040000   1.000     
1.000   

95000231 O    Banana-babyfood                    0.040000   1.000     
1.000   

95000240 O    Banana, dried                      0.040000   3.900     
1.000   

95000241 O    Banana, dried-babyfood             0.040000   3.900     
1.000   

15000250 15   Barley, pearled barley             1.400000   1.000     
0.010   PP#7E7

  Full comment: PP#7E7245

15000251 15   Barley, pearled barley-babyfood    1.400000   1.000     
0.010   PP#7E7

  Full comment: PP#7E7245

15000260 15   Barley, flour                      1.400000   1.000     
0.010   PP#7E7

  Full comment: PP#7E7245

15000261 15   Barley, flour-babyfood             1.400000   1.000     
0.010   PP#7E7

  Full comment: PP#7E7245

15000270 15   Barley, bran                       1.400000   1.000     
0.010   PP#7E7

  Full comment: PP#7E7245

19010280 19A  Basil, fresh leaves               25.000000   1.000     
1.000   PP#6E7

  Full comment: PP#6E7165

19010281 19A  Basil, fresh leaves-babyfood      25.000000   1.000     
1.000   PP#6E7

  Full comment: PP#6E7165

19010290 19A  Basil, dried leaves               85.000000   1.000     
1.000   PP#6E7

  Full comment: PP#6E7165

19010291 19A  Basil, dried leaves-babyfood      85.000000   1.000     
1.000   PP#6E7

  Full comment: PP#6E7165

06030300 6C   Bean, black, seed                  0.500000   1.000     
0.050   

06020310 6B   Bean, broad, succulent             0.500000   1.000     
0.025   

06030320 6C   Bean, broad, seed                  0.500000   1.000     
0.050   

06020330 6B   Bean, cowpea, succulent            0.500000   1.000     
0.025   

06030340 6C   Bean, cowpea, seed                 0.500000   1.000     
0.050   

06030350 6C   Bean,  great northern, seed        0.500000   1.000     
0.050   

06030360 6C   Bean, kidney, seed                 0.500000   1.000     
0.050   

06020370 6B   Bean, lima, succulent              0.500000   1.000     
0.025   

06030380 6C   Bean, lima, seed                   0.500000   1.000     
0.050   

06030390 6C   Bean, mung, seed                   0.500000   1.000     
0.050   

06030400 6C   Bean, navy, seed                   0.500000   1.000     
0.050   

06030410 6C   Bean, pink, seed                   0.500000   1.000     
0.050   

06030420 6C   Bean, pinto, seed                  0.500000   1.000     
0.050   

06010430 6A   Bean, snap, succulent              0.500000   1.000     
0.025   

06010431 6A   Bean, snap, succulent-babyfood     0.500000   1.000     
0.025   

21000440 M    Beef, meat                         0.100000   1.000     
1.000   

21000441 M    Beef, meat-babyfood                0.100000   1.000     
1.000   

21000450 M    Beef, meat, dried                  0.100000   1.920     
1.000   

21000460 M    Beef, meat byproducts              0.200000   1.000     
1.000   

21000461 M    Beef, meat byproducts-babyfood     0.200000   1.000     
1.000   

21000470 M    Beef, fat                          0.100000   1.000     
1.000   

21000471 M    Beef,fat-babyfood                  0.100000   1.000     
1.000   

21000480 M    Beef, kidney                       0.200000   1.000     
1.000   

21000490 M    Beef, liver                        1.500000   1.000     
1.000   

21000491 M    Beef, liver-babyfood               1.500000   1.000     
1.000   

01010500 1AB  Beet, garden, roots                0.400000   1.000     
1.000   

01010501 1AB  Beet, garden, roots-babyfood       0.400000   1.000     
1.000   

02000510 2    Beet, garden, tops                16.000000   1.000     
1.000   

01010520 1A   Beet, sugar                        0.200000   0.400     
0.350   

01010521 1A   Beet, sugar-babyfood               0.200000   0.400     
0.350   

01010530 1A   Beet, sugar, molasses              0.200000   0.400     
0.350   

01010531 1A   Beet, sugar, molasses-babyfood     0.200000   0.400     
0.350   

95000540 O    Belgium endive                    11.000000   1.000     
1.000   

13010550 13A  Blackberry                         4.000000   1.000     
0.200   

13010560 13A  Blackberry, juice                  4.000000   1.000     
0.200   

13010561 13A  Blackberry, juice-babyfood         4.000000   1.000     
0.200   

13020570 13B  Blueberry                          4.000000   1.000     
0.200   

13020571 13B  Blueberry-babyfood                 4.000000   1.000     
0.200   

13010580 13A  Boysenberry                        4.000000   1.000     
1.000   

14000590 14   Brazil nut                         0.040000   1.000     
1.000   

05010610 5A   Broccoli                           1.100000   1.000     
0.050   

05010611 5A   Broccoli-babyfood                  1.100000   1.000     
0.050   

05010620 5A   Broccoli, Chinese                  1.100000   1.000     
0.050   

05020630 5B   Broccoli raab                      5.740000   1.000     
1.000   

05010640 5A   Brussels sprouts                   5.000000   1.000     
1.000   

01010670 1AB  Burdock                            0.400000   1.000     
1.000   

14000680 14   Butternut                          0.040000   1.000     
1.000   

05010690 5A   Cabbage                            5.000000   1.000     
0.100   

05020700 5B   Cabbage, Chinese, bok choy         5.740000   1.000     
1.000   

05010710 5A   Cabbage, Chinese, napa             5.000000   1.000     
0.100   

05010720 5A   Cabbage, Chinese, mustard          5.000000   1.000     
0.100   

95000740 O    Canistel                           0.600000   1.000     
1.000   PP#6E7

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09010750 9A   Cantaloupe                         0.500000   1.000     
0.150   

04020760 4B   Cardoon                           11.770000   1.000     
1.000   

01010780 1AB  Carrot                             0.400000   1.000     
0.250   

01010781 1AB  Carrot-babyfood                    0.400000   1.000     
0.250   

01010790 1AB  Carrot, juice                      0.400000   1.000     
0.250   

09010800 9A   Casaba                             0.500000   1.000     
1.000   

14000810 14   Cashew                             0.040000   1.000     
1.000   

01030820 1CD  Cassava                            0.040000   1.000     
1.000   

01030821 1CD  Cassava-babyfood                   0.040000   1.000     
1.000   

05010830 5A   Cauliflower                        5.000000   1.000     
1.000   

01010840 1AB  Celeriac                           0.400000   1.000     
1.000   

04020850 4B   Celery                             5.020000   1.000     
0.025   

04020851 4B   Celery-babyfood                    5.020000   1.000     
0.025   

04020860 4B   Celery, juice                      5.020000   1.000     
0.025   

04020870 4B   Celtuce                            5.020000   1.000     
1.000   

09020880 9B   Chayote, fruit                     0.500000   1.000     
1.000   

12000900 12   Cherry                             0.846000   1.000     
0.300   

12000901 12   Cherry-babyfood                    0.846000   1.000     
0.300   

12000910 12   Cherry, juice                      0.846000   1.500     
0.300   

12000911 12   Cherry, juice-babyfood             0.846000   1.500     
0.300   

14000920 14   Chestnut                           0.040000   1.000     
1.000   

06030980 6C   Chickpea, seed                     0.340000   1.000     
1.000   

06030981 6C   Chickpea, seed-babyfood            0.340000   1.000     
1.000   

06030990 6C   Chickpea, flour                    0.340000   1.000     
1.000   

01011000 1AB  Chicory, roots                     0.400000   1.000     
1.000   

02001010 2    Chicory, tops                     16.000000   1.000     
1.000   

09021020 9B   Chinese waxgourd                   0.500000   1.000     
1.000   

19011030 19A  Chive                             25.000000   1.000     
1.000   PP#6E7

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04011040 4A   Chrysanthemum, garland            11.770000   1.000     
1.000   

10001060 10   Citrus citron                      2.000000   1.000     
1.000   

10001070 10   Citrus hybrids                     2.000000   1.000     
1.000   

10001080 10   Citrus, oil                        9.000000   1.000     
1.000   

95001150 O    Coffee, roasted bean               0.064000   1.000     
1.000   

95001160 O    Coffee, instant                    0.064000   1.000     
1.000   

05021170 5B   Collards                           5.740000   1.000     
1.000   

19011180 19A  Coriander, leaves                 25.000000   1.000     
1.000   PP#6E7

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19011181 19A  Coriander, leaves-babyfood        25.000000   1.000     
1.000   PP#6E7

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15001200 15   Corn, field, flour                 0.100000   1.000     
0.050   

15001201 15   Corn, field, flour-babyfood        0.100000   1.000     
0.050   

15001210 15   Corn, field, meal                  0.100000   1.000     
0.050   

15001211 15   Corn, field, meal-babyfood         0.100000   1.000     
0.050   

15001220 15   Corn, field, bran                  0.100000   1.000     
0.050   

15001230 15   Corn, field, starch                0.100000   1.000     
0.050   

15001231 15   Corn, field, starch-babyfood       0.100000   1.000     
0.050   

15001240 15   Corn, field, syrup                 0.100000   1.500     
0.050   

15001241 15   Corn, field, syrup-babyfood        0.100000   1.500     
0.050   

15001250 15   Corn, field, oil                   0.200000   1.000     
0.050   

15001251 15   Corn, field, oil-babyfood          0.200000   1.000     
0.050   

15001260 15   Corn, pop                          0.100000   1.000     
0.050   

15001270 15   Corn, sweet                        0.040000   1.000     
0.050   

15001271 15   Corn, sweet-babyfood               0.040000   1.000     
0.050   

95001280 O    Cottonseed, oil                    0.300000   0.300     
1.000   

95001281 O    Cottonseed, oil-babyfood           0.300000   0.300     
1.000   

11001290 11   Crabapple                          1.500000   1.000     
1.000   

04011330 4A   Cress, garden                     11.770000   1.000     
1.000   

04011340 4A   Cress, upland                     11.770000   1.000     
1.000   

09021350 9B   Cucumber

                110-Uncooked; Fresh or N/S; Cook Meth N/S

                                                 0.500000   1.000     
0.050   

                150-Uncooked; Cured etc; Cook Meth N/S

                                                 0.500000   1.000     
0.050   

                210-Cooked; Fresh or N/S; Cook Meth N/S

                                                 0.500000   1.000     
0.050   

                212-Cooked; Fresh or N/S; Boiled

                                                 0.500000   1.000     
0.050   

                240-Cooked; Canned; Cook Meth N/S

                                                 0.500000   1.000     
0.050   

13021360 13B  Currant                            4.000000   1.000     
1.000   

13021370 13B  Currant, dried                     4.000000   1.000     
1.000   

04011380 4A   Dandelion, leaves                 11.770000   1.000     
1.000   

01031390 1CD  Dasheen, corm                      0.040000   1.000     
1.000   

02001400 2    Dasheen, leaves                   16.000000   1.000     
1.000   

13011420 13A  Dewberry                           4.000000   1.000     
1.000   

19021430 19B  Dill, seed                        25.000000   1.000     
1.000   PP#6E7

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19011440 19A  Dillweed                          25.000000   1.000     
1.000   PP#6E7

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08001480 8    Eggplant                           1.400000   1.000     
1.000   

13021490 13B  Elderberry                         4.000000   1.000     
1.000   

04011500 4A   Endive                            11.770000   1.000     
1.000   

04021520 4B   Fennel, Florence                   5.020000   1.000     
1.000   

14001550 14   Filbert                            0.040000   1.000     
0.100   

14001560 14   Filbert, oil                       0.040000   1.000     
0.100   

20001630 20   Flaxseed, oil                      0.450000   1.200     
1.000   PP#6E7

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03001640 3    Garlic                             0.900000   1.000     
0.100   

03001650 3    Garlic, dried                      0.900000   1.000     
0.100   

03001651 3    Garlic, dried-babyfood             0.900000   1.000     
0.100   

01031660 1CD  Ginger                             0.040000   1.000     
1.000   

01031661 1CD  Ginger-babyfood                    0.040000   1.000     
1.000   

01031670 1CD  Ginger, dried                      0.040000   1.000     
1.000   

01011680 1AB  Ginseng, dried                     0.400000   1.000     
1.000   

23001690 M    Goat, meat                         0.100000   1.000     
1.000   

23001700 M    Goat, meat byproducts              0.200000   1.000     
1.000   

23001710 M    Goat, fat                          0.100000   1.000     
1.000   

23001720 M    Goat, kidney                       0.200000   1.000     
1.000   

23001730 M    Goat, liver                        1.500000   1.000     
1.000   

13021740 13B  Gooseberry                         4.000000   1.000     
1.000   

95001750 O    Grape                              0.768000   1.000     
0.250   

95001760 O    Grape, juice                       0.768000   0.010     
0.250   

95001761 O    Grape, juice-babyfood              0.768000   0.010     
0.250   

95001770 O    Grape, leaves                      0.768000   1.000     
0.250   

95001780 O    Grape, raisin                      7.000000   1.000     
0.250   

95001790 O    Grape, wine and sherry             0.768000   1.000     
0.250   

10001800 10   Grapefruit                         2.000000   1.000     
0.250   

10001810 10   Grapefruit, juice                  2.000000   0.020     
0.250   

06031820 6C   Guar, seed                         0.500000   1.000     
1.000   

06031821 6C   Guar, seed-babyfood                0.500000   1.000     
1.000   

19011840 19A  Herbs, other                      25.000000   1.000     
1.000   PP#6E7

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19011841 19A  Herbs, other-babyfood             25.000000   1.000     
1.000   PP#6E7

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14001850 14   Hickory nut                        0.040000   1.000     
1.000   

09011870 9A   Honeydew melon                     0.500000   1.000     
1.000   

95001880 O    Hop                               23.000000   1.000     
1.000   

24001890 M    Horse, meat                        0.100000   1.000     
1.000   

01011900 1AB  Horseradish                        0.400000   1.000     
1.000   

13021910 13B  Huckleberry                        4.000000   1.000     
1.000   

05021940 5B   Kale                               5.740000   1.000     
1.000   

05011960 5A   Kohlrabi                           5.000000   1.000     
1.000   

10001970 10   Kumquat                            2.000000   1.000     
1.000   

03001980 3    Leek                               0.900000   1.000     
1.000   

10001990 10   Lemon                              2.000000   1.000     
1.000   

10002000 10   Lemon, juice                       2.000000   0.020     
1.000   

10002001 10   Lemon, juice-babyfood              2.000000   0.020     
1.000   

10002010 10   Lemon, peel                        2.000000   1.000     
1.000   

19012020 19A  Lemongrass                        25.000000   1.000     
1.000   PP#6E7

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06032030 6C   Lentil, seed                       0.500000   1.000     
1.000   

04012040 4A   Lettuce, head                      0.590000   1.000     
0.050   

04012050 4A   Lettuce, leaf                      7.680000   1.000     
0.050   

10002060 10   Lime                               2.000000   1.000     
1.000   

10002070 10   Lime, juice                        2.000000   0.020     
1.000   

10002071 10   Lime, juice-babyfood               2.000000   0.020     
1.000   

13012080 13A  Loganberry                         4.000000   1.000     
1.000   

11002100 11   Loquat                             1.500000   1.000     
1.000   

14002130 14   Macadamia nut                      0.040000   1.000     
1.000   

95002140 O    Mamey apple                        0.600000   1.000     
1.000   PP#6E7

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95002150 O    Mango                              0.600000   1.000     
1.000   PP#6E7

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95002151 O    Mango-babyfood                     0.600000   1.000     
1.000   PP#6E7

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95002160 O    Mango, dried                       0.600000   1.000     
1.000   PP#6E7

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95002170 O    Mango, juice                       0.600000   1.000     
1.000   PP#6E7

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95002171 O    Mango, juice-babyfood              0.600000   1.000     
1.000   PP#6E7

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19012200 19A  Marjoram                          25.000000   1.000     
1.000   PP#6E7

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19012201 19A  Marjoram-babyfood                 25.000000   1.000     
1.000   PP#6E7

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27002220 D    Milk, fat                          0.100000   1.000     
1.000   

27002221 D    Milk, fat - baby food/infant for   0.100000   1.000     
1.000   

27012230 D    Milk, nonfat solids                0.100000   1.000     
1.000   

27012231 D    Milk, nonfat solids-baby food/in   0.100000   1.000     
1.000   

27022240 D    Milk, water                        0.100000   1.000     
1.000   

27022241 D    Milk, water-babyfood/infant form   0.100000   1.000     
1.000   

27032251 D    Milk, sugar (lactose)-baby food/   0.100000   1.000     
1.000   

05022290 5B   Mustard greens                     5.740000   1.000     
1.000   

12002300 12   Nectarine                          0.602000   1.000     
0.150   

15002310 15   Oat, bran                          1.200000   1.000     
1.000   PP#6E7

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15002320 15   Oat, flour                         1.200000   1.000     
1.000   PP#6E7

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15002321 15   Oat, flour-babyfood                1.200000   1.000     
1.000   PP#6E7

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15002330 15   Oat, groats/rolled oats            1.200000   1.000     
1.000   PP#6E7

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15002331 15   Oat, groats/rolled oats-babyfood   1.200000   1.000     
1.000   PP#6E7

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08002340 8    Okra                               1.400000   1.000     
1.000   

03002370 3    Onion, dry bulb                    0.900000   1.000     
0.150   

03002371 3    Onion, dry bulb-babyfood           0.900000   1.000     
0.150   

03002380 3    Onion, dry bulb, dried             0.900000   9.000     
0.150   

03002381 3    Onion, dry bulb, dried-babyfood    0.900000   9.000     
0.150   

03002390 3    Onion, green                       0.900000   1.000     
0.150   

10002400 10   Orange                             0.300000   1.000     
0.050   

10002410 10   Orange, juice                      0.300000   0.020     
0.050   

10002411 10   Orange, juice-babyfood             0.300000   0.020     
0.050   

10002420 10   Orange, peel                       0.300000   1.000     
0.050   

95002450 O    Papaya                             0.600000   1.000     
1.000   PP#6E7

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95002451 O    Papaya-babyfood                    0.600000   1.000     
1.000   PP#6E7

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95002460 O    Papaya, dried                      0.600000   1.800     
1.000   PP#6E7

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95002470 O    Papaya, juice                      0.600000   1.500     
1.000   PP#6E7

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04012480 4A   Parsley, leaves                   11.770000   1.000     
1.000   

19012490 19A  Parsley, dried leaves             85.000000   1.000     
1.000   PP#6E7

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19012491 19A  Parsley, dried leaves-babyfood    85.000000   1.000     
1.000   PP#6E7

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01012500 1AB  Parsley, turnip rooted             0.400000   1.000     
1.000   

01012510 1AB  Parsnip                            0.400000   1.000     
1.000   

01012511 1AB  Parsnip-babyfood                   0.400000   1.000     
1.000   

06022550 6B   Pea, succulent                     0.200000   1.000     
0.050   

06022551 6B   Pea, succulent-babyfood            0.200000   1.000     
0.050   

06032560 6C   Pea, dry                           0.500000   1.000     
1.000   

06032561 6C   Pea, dry-babyfood                  0.500000   1.000     
1.000   

06012570 6A   Pea, edible podded, succulent      0.500000   1.000     
1.000   

06032580 6C   Pea, pigeon, seed                  0.500000   1.000     
1.000   

06022590 6B   Pea, pigeon, succulent             0.200000   1.000     
0.050   

12002600 12   Peach                              0.602000   1.000     
0.150   

12002601 12   Peach-babyfood                     0.602000   1.000     
0.150   

12002610 12   Peach, dried                       0.602000   7.000     
0.150   

12002611 12   Peach, dried-babyfood              0.602000   7.000     
0.150   

12002620 12   Peach, juice                       0.602000   1.000     
0.150   

12002621 12   Peach, juice-babyfood              0.602000   1.000     
0.150   

95002630 O    Peanut                             0.050000   1.000     
0.250   

95002640 O    Peanut, butter                     0.050000   1.890     
0.250   

95002650 O    Peanut, oil                        0.100000   1.000     
0.250   

11002660 11   Pear                               1.500000   1.000     
0.100   

11002661 11   Pear-babyfood                      1.500000   1.000     
0.100   

11002670 11   Pear, dried                        1.500000   6.250     
0.100   

11002680 11   Pear, juice                        1.500000   1.000     
0.100   

11002681 11   Pear, juice-babyfood               1.500000   1.000     
0.100   

14002690 14   Pecan                              0.040000   1.000     
0.025   

08002700 8    Pepper, bell                       1.400000   1.000     
0.100   

08002701 8    Pepper, bell-babyfood              1.400000   1.000     
0.100   

08002710 8    Pepper, bell, dried                1.400000   1.000     
0.100   

08002711 8    Pepper, bell, dried-babyfood       1.400000   1.000     
0.100   

08002720 8    Pepper, nonbell                    1.400000   1.000     
0.100   

08002721 8    Pepper, nonbell-babyfood           1.400000   1.000     
0.100   

08002730 8    Pepper, nonbell, dried             1.400000   1.000     
0.100   

95002750 O    Peppermint                         8.000000   1.000     
1.000   

95002760 O    Peppermint, oil                    8.000000   1.000     
1.000   

14002820 14   Pistachio                          0.700000   1.000     
0.250   

95002830 O    Plantain                           0.040000   1.000     
1.000   

95002840 O    Plantain, dried                    0.040000   3.900     
1.000   

12002850 12   Plum                               0.198000   1.000     
0.050   

12002851 12   Plum-babyfood                      0.198000   1.000     
0.050   

12002860 12   Plum, prune, fresh                 0.198000   1.000     
0.050   

12002861 12   Plum, prune, fresh-babyfood        0.198000   1.000     
0.050   

12002870 12   Plum, prune, dried                 0.198000   1.300     
0.050   

12002871 12   Plum, prune, dried-babyfood        0.198000   1.300     
0.050   

12002880 12   Plum, prune, juice                 0.198000   1.400     
0.050   

12002881 12   Plum, prune, juice-babyfood        0.198000   1.400     
0.050   

25002900 M    Pork, meat                         0.100000   1.000     
1.000   

25002901 M    Pork, meat-babyfood                0.100000   1.000     
1.000   

25002910 M    Pork, skin                         0.100000   1.000     
1.000   

25002920 M    Pork, meat byproducts              0.200000   1.000     
1.000   

25002921 M    Pork, meat byproducts-babyfood     0.200000   1.000     
1.000   

25002930 M    Pork, fat                          0.100000   1.000     
1.000   

25002931 M    Pork, fat-babyfood                 0.100000   1.000     
1.000   

25002940 M    Pork, kidney                       0.200000   1.000     
1.000   

25002950 M    Pork, liver                        1.500000   1.000     
1.000   

01032960 1C   Potato, chips                      0.040000   1.000     
0.100   

01032970 1C   Potato, dry (granules/ flakes)     0.040000   6.500     
0.100   

01032971 1C   Potato, dry (granules/ flakes)-b   0.040000   6.500     
0.100   

01032980 1C   Potato, flour                      0.040000   6.500     
0.100   

01032981 1C   Potato, flour-babyfood             0.040000   6.500     
0.100   

01032990 1C   Potato, tuber, w/peel              0.040000   1.000     
0.100   

01032991 1C   Potato, tuber, w/peel-babyfood     0.040000   1.000     
1.000   

01033000 1C   Potato, tuber, w/o peel            0.040000   1.000     
0.100   

01033001 1C   Potato, tuber, w/o peel-babyfood   0.040000   1.000     
0.100   

10003070 10   Pummelo                            2.000000   1.000     
1.000   

09023080 9B   Pumpkin                            0.500000   1.000     
0.200   

09023090 9B   Pumpkin, seed                      0.500000   1.000     
0.200   

11003100 11   Quince                             1.500000   1.000     
1.000   

04013130 4A   Radicchio                          0.590000   1.000     
1.000   

01013140 1AB  Radish, roots                      0.400000   1.000     
1.000   

02003150 2    Radish, tops                      16.000000   1.000     
1.000   

01013160 1AB  Radish, Oriental, roots            0.400000   1.000     
1.000   

02003170 2    Radish, Oriental, tops            16.000000   1.000     
1.000   

05023180 5B   Rape greens                        5.740000   1.000     
1.000   

20003190 20   Rapeseed, oil                      0.450000   1.000     
1.000   PP#6E7

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20003191 20   Rapeseed, oil-babyfood             0.450000   1.000     
1.000   PP#6E7

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13013200 13A  Raspberry                          4.000000   1.000     
0.350   

13013201 13A  Raspberry-babyfood                 4.000000   1.000     
0.350   

13013210 13A  Raspberry, juice                   4.000000   1.000     
0.350   

13013211 13A  Raspberry, juice-babyfood          4.000000   1.000     
0.350   

04023220 4B   Rhubarb                            5.020000   1.000     
1.000   

01013270 1AB  Rutabaga                           0.400000   1.000     
1.000   

15003280 15   Rye, grain                         0.040000   1.000     
1.000   

15003290 15   Rye, flour                         0.040000   1.000     
1.000   

20003300 20   Safflower, oil                     0.450000   1.000     
1.000   PP#6E7

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20003301 20   Safflower, oil-babyfood            0.450000   1.000     
1.000   PP#6E7

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01013310 1AB  Salsify, roots                     0.400000   1.000     
1.000   

02003320 2    Salsify, tops                     16.000000   1.000     
1.000   

95003330 O    Sapote, Mamey                      0.600000   1.000     
1.000   PP#6E7

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19013340 19A  Savory                            25.000000   1.000     
1.000   PP#6E7

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95003360 O    Sesame, seed                       0.450000   1.000     
1.000   PP#6E7

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95003361 O    Sesame, seed-babyfood              0.450000   1.000     
1.000   PP#6E7

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95003370 O    Sesame, oil                        0.450000   1.000     
1.000   PP#6E7

  Full comment: PP#6E7105

95003371 O    Sesame, oil-babyfood               0.450000   1.000     
1.000   PP#6E7

  Full comment: PP#6E7105

03003380 3    Shallot                            0.900000   1.000     
1.000   

26003390 M    Sheep, meat                        0.100000   1.000     
1.000   

26003391 M    Sheep, meat-babyfood               0.100000   1.000     
1.000   

26003400 M    Sheep, meat byproducts             0.200000   1.000     
1.000   

26003410 M    Sheep, fat                         0.100000   1.000     
1.000   

26003411 M    Sheep, fat-babyfood                0.100000   1.000     
1.000   

26003420 M    Sheep, kidney                      0.200000   1.000     
1.000   

26003430 M    Sheep, liver                       1.500000   1.000     
1.000   

15003440 15   Sorghum, grain                     0.090000   1.000     
1.000   

15003450 15   Sorghum, syrup                     0.090000   1.000     
1.000   

06003470 6    Soybean, seed                      0.040000   1.000     
0.050   

06003480 6    Soybean, flour                     0.040000   1.000     
0.050   

06003481 6    Soybean, flour-babyfood            0.040000   1.000     
0.050   

06003490 6    Soybean, soy milk                  0.040000   1.000     
0.050   

06003491 6    Soybean, soy milk-babyfood or in   0.040000   1.000     
0.050   

06003500 6    Soybean, oil                       0.040000   1.000     
0.050   

06003501 6    Soybean, oil-babyfood              0.040000   1.000     
0.050   

95003520 O    Spearmint                          8.000000   1.000     
1.000   

95003530 O    Spearmint, oil                     8.000000   1.000     
1.000   

04013550 4A   Spinach                           11.770000   1.000     
0.100   

04013551 4A   Spinach-babyfood                  11.770000   1.000     
0.100   

09023560 9B   Squash, summer                     0.500000   1.000     
0.100   

09023561 9B   Squash, summer-babyfood            0.500000   1.000     
0.100   

09023570 9B   Squash, winter                     0.500000   1.000     
0.100   

09023571 9B   Squash, winter-babyfood            0.500000   1.000     
0.100   

95003590 O    Strawberry                         1.200000   1.000     
0.500   

95003591 O    Strawberry-babyfood                1.200000   1.000     
0.500   

95003600 O    Strawberry, juice                  1.200000   1.000     
0.500   

95003601 O    Strawberry, juice-babyfood         1.200000   1.000     
0.500   

95003620 O    Sugarcane, sugar                   0.020000   1.000     
1.000   

95003621 O    Sugarcane, sugar-babyfood          0.020000   1.000     
1.000   

95003630 O    Sugarcane, molasses                0.400000   1.000     
1.000   

95003631 O    Sugarcane, molasses-babyfood       0.400000   1.000     
1.000   

20003640 20   Sunflower, seed                    0.450000   1.000     
1.000   PP#6E7

  Full comment: PP#6E7105

20003650 20   Sunflower, oil                     0.450000   1.000     
1.000   PP#6E7

  Full comment: PP#6E7105

20003651 20   Sunflower, oil-babyfood            0.450000   1.000     
1.000   PP#6E7

  Full comment: PP#6E7105

01033660 1CD  Sweet potato                       0.040000   1.000     
1.000   

01033661 1CD  Sweet potato-babyfood              0.040000   1.000     
1.000   

04023670 4B   Swiss chard                        5.020000   1.000     
1.000   

10003690 10   Tangerine                          2.000000   1.000     
0.150   

10003700 10   Tangerine, juice                   2.000000   0.020     
0.150   

01033710 1CD  Tanier, corm                       0.040000   1.000     
1.000   

08003740 8    Tomatillo                          1.400000   1.000     
1.000   

08003750 8    Tomato                             0.158000   1.000     
0.200   

08003751 8    Tomato-babyfood                    0.158000   1.000     
0.200   

08003760 8    Tomato, paste                      0.158000   2.100     
0.200   

08003761 8    Tomato, paste-babyfood             0.158000   2.100     
0.200   

08003770 8    Tomato, puree                      0.158000   0.550     
0.200   

08003771 8    Tomato, puree-babyfood             0.158000   0.550     
0.200   

08003780 8    Tomato, dried                      0.158000  14.300     
0.200   

08003781 8    Tomato, dried-babyfood             0.158000  14.300     
0.200   

08003790 8    Tomato, juice                      0.158000   1.500     
0.200   

15003810 15   Triticale, flour                   0.200000   0.700     
1.000   

15003811 15   Triticale, flour-babyfood          0.200000   0.700     
1.000   

01033870 1CD  Turmeric                           0.040000   1.000     
1.000   

01013880 1AB  Turnip, roots                      0.400000   1.000     
1.000   

05023890 5B   Turnip, greens                     5.740000   1.000     
1.000   

14003910 14   Walnut                             0.040000   1.000     
1.000   

86010000 O    Water, direct, all sources         0.002300   1.000     
1.000   

86020000 O    Water, indirect, all sources       0.002300   1.000     
1.000   

09013990 9A   Watermelon                         0.500000   1.000     
0.300   

09014000 9A   Watermelon, juice                  0.500000   1.000     
0.300   

15004010 15   Wheat, grain                       0.200000   1.000     
0.050   

15004011 15   Wheat, grain-babyfood              0.200000   1.000     
0.050   

15004020 15   Wheat, flour                       0.200000   0.700     
0.050   

15004021 15   Wheat, flour-babyfood              0.200000   0.700     
0.050   

15004030 15   Wheat, germ                        0.200000   0.850     
0.050   

15004040 15   Wheat, bran                        0.200000   1.000     
0.050   

01034060 1CD  Yam, true                          0.040000   1.000     
1.000   

01034070 1CD  Yam bean                           0.040000   1.000     
1.000   

Attachment 5.  Pyraclostrobin Refined Chronic Dietary Analysis Results
– Food alone

U.S. Environmental Protection Agency                                
Ver. 2.00

DEEM-FCID Chronic analysis for PYRACLOSTROBIN                   (1994-98
data)

Residue file name:
C:\DEEMFCID\Pyraclostrobin\Pyraclostrobin_ChronicSLUAFood.R98

                                                     Adjustment factor
#2 used.

Analysis Date 03-31-2009/16:48:00     Residue file dated:
03-31-2009/15:56:25/8

Reference dose (RfD, Chronic) = .034 mg/kg bw/day

COMMENT 1: Chronic-new use sorghum grain, coffee, stone fruits (Food
alone).

========================================================================
=======

                    Total exposure by population subgroup

------------------------------------------------------------------------
-------

                                                    Total Exposure

                                        
-----------------------------------

          Population                         mg/kg             Percent
of   

           Subgroup                       body wt/day             Rfd   
   

--------------------------------------   -------------      
---------------

U.S. Population (total)                     0.002417                
7.1%

U.S. Population (spring season)             0.002506                
7.4%

U.S. Population (summer season)             0.002453                
7.2%

U.S. Population (autumn season)             0.002378                
7.0%

U.S. Population (winter season)             0.002330                
6.9%

Northeast region                            0.002451                
7.2%

Midwest region                              0.002424                
7.1%

Southern region                             0.002237                
6.6%

Western region                              0.002664                
7.8%

Hispanics                                   0.002460                
7.2%

Non-hispanic whites                         0.002320                
6.8%

Non-hispanic blacks                         0.002724                
8.0%

Non-hisp/non-white/non-black                0.003032                
8.9%

All infants (< 1 year)                      0.003523               
10.4%

Nursing infants                             0.001533                
4.5%

Non-nursing infants                         0.004278               
12.6%

Children 1-6  yrs                           0.006297               
18.5%

Children 7-12 yrs                           0.003042                
8.9%

Females 13-19 (not preg or nursing)         0.001612                
4.7%

Females 20+ (not preg or nursing)           0.001780                
5.2%

Females 13-50 yrs                           0.001825                
5.4%

Females 13+ (preg/not nursing)              0.001773                
5.2%

Females 13+ (nursing)                       0.002032                
6.0%

Males 13-19 yrs                             0.002124                
6.2%

Males 20+ yrs                               0.001973                
5.8%

Seniors 55+                                 0.001963                
5.8%

Children 1-2 yrs                            0.007960               
23.4%

Children 3-5 yrs                            0.005760               
16.9%

Children 6-12 yrs                           0.003277                
9.6%

Youth 13-19 yrs                             0.001873                
5.5%

Adults 20-49 yrs                            0.001830                
5.4%

Adults 50+ yrs                              0.001952                
5.7%

Females 13-49 yrs                           0.001672                
4.9%

------------------------------------------------------------------------
-------

 

Attachment 6.  Pyraclostrobin Refined Chronic Dietary Analysis Results
– Food & Water

U.S. Environmental Protection Agency                                
Ver. 2.00

DEEM-FCID Chronic analysis for PYRACLOSTROBIN                   (1994-98
data)

Residue file name:
C:\DEEMFCID\Pyraclostrobin\Pyraclostrobin_ChronicSLUA.R98

                                                     Adjustment factor
#2 used.

Analysis Date 03-31-2009/16:50:08     Residue file dated:
03-31-2009/15:55:39/8

Reference dose (RfD, Chronic) = .034 mg/kg bw/day

COMMENT 1: Chronic-new use sorghum grain, coffee, stone fruits (Food and
drinking water), SLUA-PCT

========================================================================
=======

                    Total exposure by population subgroup

------------------------------------------------------------------------
-------

                                                    Total Exposure

                                        
-----------------------------------

          Population                         mg/kg             Percent
of   

           Subgroup                       body wt/day             Rfd   
   

--------------------------------------   -------------      
---------------

U.S. Population (total)                     0.002466                
7.3%

U.S. Population (spring season)             0.002554                
7.5%

U.S. Population (summer season)             0.002505                
7.4%

U.S. Population (autumn season)             0.002425                
7.1%

U.S. Population (winter season)             0.002377                
7.0%

Northeast region                            0.002496                
7.3%

Midwest region                              0.002473                
7.3%

Southern region                             0.002283                
6.7%

Western region                              0.002720                
8.0%

Hispanics                                   0.002515                
7.4%

Non-hispanic whites                         0.002367                
7.0%

Non-hispanic blacks                         0.002770                
8.1%

Non-hisp/non-white/non-black                0.003092                
9.1%

All infants (< 1 year)                      0.003682               
10.8%

Nursing infants                             0.001592                
4.7%

Non-nursing infants                         0.004475               
13.2%

Children 1-6  yrs                           0.006364               
18.7%

Children 7-12 yrs                           0.003086                
9.1%

Females 13-19 (not preg or nursing)         0.001647                
4.8%

Females 20+ (not preg or nursing)           0.001828                
5.4%

Females 13-50 yrs                           0.001872                
5.5%

Females 13+ (preg/not nursing)              0.001820                
5.4%

Females 13+ (nursing)                       0.002099                
6.2%

Males 13-19 yrs                             0.002160                
6.4%

Males 20+ yrs                               0.002016                
5.9%

Seniors 55+                                 0.002010                
5.9%

 

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     0.001908                 5.6%

Adults 20-49 yrs                            0.001875                
5.5%

Adults 50+ yrs                              0.002000                
5.9%

Females 13-49 yrs                           0.001717                
5.1%

------------------------------------------------------------------------
-------

Attachment 7.  Pyraclostrobin Screening Level Usage Analysis (SLUA)

                                 

                                       



Pyraclostrobin	Dietary Exposure and Risk Assessment	DP Number: 359194		

________________________________________________________________________
___________ 

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   Page   PAGE  1  of   NUMPAGES  33