Document ID: EPA-HQ-OPP-2006-0875-0009
Agency: epa
Document Type: Supporting & Related Material
Title: 
Posted Date: 2009-03-25T04:00Z

SEQ CHAPTER \h \r 1 

UNITED STATES ENVIRONMENTAL PROTECTION AGENCY

WASHINGTON, D.C. 20460      

	OFFICE OF PREVENTION, PESTICIDESs

                                                                        
                   AND TOXIC SUBSTANCES

	

MEMORANDUM

Date:  		26-Nov-2008  

SUBJECT:	Fenpropathrin Acute Probabilistic and Chronic Aggregate Dietary
(Food and Drinking Water) Exposure and Risk Assessment for the Section 3
Registration Action

PC Code:  127901	DP Barcode:  356137 

Decision No.: 351279, 366994, & 386849	Registration No.: 59639-35

Petition No.: 6E7066, 4E6867, & 7E7298	Regulatory Action: Section 3

Risk Assessment Type: Dietary	Case No.: NA

TXR No.: NA	CAS No.: 39515-41-8

MRID No.: NA	40 CFR:  180.466

FROM:	Anant Parmar, Biologist

Registration Action Branch 2/Health Effects Division (7509P)

THROUGH:	Douglas Dotson, Ph.D., Chemist

Thurston Morton, Chemist

Dietary Exposure Science Advisory Council (DESAC)

Health Effects Division (7509P)

and

William H. Donovan, Ph.D., Senior Scientist

Registration Action Branch 3/Health Effects Division (7509P)

TO:		Douglas Dotson, Ph.D., Chemist

		RAB2/Health Effects Division (7509P)

and

Sidney Jackson/Barbara Madden, RIMUERB

Olga Odiott, Insecticide Branch

Registration Division (7505P)

Executive Summary

Acute and chronic dietary exposure assessments were conducted using the
Dietary Exposure Evaluation Model (DEEM-FCID, Version 2.03), which uses
food consumption data from the USDA’s Continuing Surveys of Food
Intakes by Individuals (CSFII) from 1994-1996 and 1998.  The analyses
were performed to support Section 3 requests for tolerances on barley,
caneberries (Crop group 13-07A), stone fruit (Crop group 12), Treenuts
(Crop group 14) and pistachio, olives, and tropical and subtropical
fruits.

   

Acute Dietary Exposure Results and Characterization

A partially refined acute probabilistic dietary exposure analysis was
performed for the insecticide fenpropathrin.  The analysis was based on
tolerance level residues for some commodities, crop field trial data for
others, processing factors, and the assumption of 100% percent crop
treated for all commodities.  At the 95th percentile of exposure, the
risk estimate for the general U.S. population is 21% of the acute
population adjusted dose (aPAD).  The most highly exposed population
subgroup is Children 1-2 Years, which utilizes 53% of the aPAD.

Chronic Dietary Exposure Results and Characterization

A partially refined chronic dietary exposure analysis was performed for
fenpropathrin.  The analysis was based on tolerance level residues for
some commodities, crop field trial data for others, processing factors,
and the assumption of 100% percent crop treated for all commodities. 
The U.S. population and all population subgroups have dietary exposure
and risk estimates that are below HED’s level of concern.  The general
U.S. population utilizes 14% of the chronic PAD (cPAD).  The most highly
exposed subgroup, Children 1-2 Years, utilizes 41% of the cPAD.

  

Cancer Dietary Exposure Results and Characterization

A cancer dietary exposure analysis was not performed because
fenpropathrin was classified as "not likely to be carcinogenic to
humans.”

I.	Introduction

Dietary risk assessment incorporates both exposure and toxicity of a
given pesticide.  For acute and chronic assessments, the risk is
expressed as a percentage of a maximum acceptable dose (i.e., the dose
which HED has concluded will result in no unreasonable adverse health
effects).  This dose is referred to as the population adjusted dose
(PAD).  The PAD is equivalent to point of departure (POD, NOAEL, LOAEL,
e.g.) divided by the required uncertainty or safety factors.

For acute and non-cancer chronic exposures, HED is concerned when
estimated dietary risk exceeds 100% of the PAD.  HED is generally
concerned when estimated cancer risk exceeds one in one million. 
References which discuss the acute and chronic risk assessments in more
detail are available on the EPA/pesticides web site:  “Available
Information on Assessing Exposure from Pesticides, A User’s Guide,”
21-JUN-2000, web link:      HYPERLINK
"http://www.epa.gov/fedrgstr/EPA-PEST/2000/July/Day-12/6061.pdf" 
http://www.epa.gov/fedrgstr/EPA-PEST/2000/July/Day-12/6061.pdf  ; or see
SOP 99.6 (20-AUG-1999).

The most recent dietary exposure analysis for fenpropathrin was
conducted in 2005 (D313506, D. Dotson, 9/20/2005).

II.	Residue Information and Percent Crop Treated Data

Percent Crop Treated

The acute and chronic assessments are both based on the assumption of
100% crop treated for all commodities.

Food

This assessment was based on the assumption of tolerance-level residues
for some commodities and field trial data for others.  The existing
fenpropathrin tolerances are listed in 40 CFR §180.466.  HED is
currently recommending tolerances on the following raw agricultural
commodities:

Fruit, Stone, Group 12 except Cherry	1.4 ppm

Cherry, sweet & tart	5.0 ppm

Nut, Tree, Group 14	0.10 ppm

Almond, hulls	4.5 ppm

Pistachio	0.10 ppm

Avocado	1.0 ppm

Black sapote	1.0 ppm

Canistel	1.0 ppm

Mamey sapote	1.0 ppm

Mango	1.0 ppm

Papaya	1.0 ppm

Sapodilla	1.0 ppm

Star apple	1.0 ppm

Barley, grain	0.04 ppm (Withheld)

Caneberry Subgroup (13-07A)	12.0 ppm

Olive	5.0 ppm

The tolerance for barley is being withheld because of the lack of a
barley processing study.  This assessment includes barley so that an
additional dietary assessment will not need to be performed once the
requisite data are received and tolerances for barley commodities are
established.  In the event that the submitted processing factors are
higher than those used in the analyses, the dietary exposure assessments
and human health risk assessment will be updated. 

Both tolerance level residues and field trial data were used in the
analyses.  The sources for the field trial data for proposed commodities
were the individual data evaluation records (DERs) that were prepared
for those commodities.  Field trial data for registered commodities were
taken from the previous dietary exposure memos prepared for
fenpropathrin (D. Dotson, D257376 (11/1/99), D260817 (1/7/2000), and
D313506 (9/20/2005)).  Field trial data were translated from the
representative commodities in the crop groups to the non-representative
commodities according to HED SOP 2000.1: “Guidance for Translation of
Field Trial Data from Representative Commodities in the Crop Group
Regulation to Other Commodities in Each Crop Group/Subgroup.”  In both
the acute and chronic analyses field trial data rather than tolerances
were used for apples, pears, grapes, cherry, peach, and plum.  

In the chronic dietary exposure analysis, tolerances or average field
trial values were used for both blended and non-blended commodities.  A
probabilistic assessment was performed in order to determine the acute
dietary exposure estimates.  In this analysis, blended and non-blended
commodities were treated differently.  In addition, field trial data
were also treated differently.  The classification of foods as to
blending status was done according to HED’s Draft DEEM-FCID
Classification of Food Forms with Respect to Blending (F. Fort,
4/9/2003).  The blended commodities in the analysis for which field
trial values were used are dried apples, dried apricots, dried peaches,
and dried pears.  When field trial values were used for blended
commodities, the mean field trial values were calculated and used as
point estimates.  When field trial values were used for non-blended and
partially blended commodities, all individual field trial values were
used to create a residue distribution file (RDF).  

Attachment 5 provides the RDFs used in the analyses.  Each RDF gives the
individual field trial value, the mean value, the number of samples, and
the number of detects.  In preparing the RDF, a value of ½ LOQ was used
for samples which were reported to have residues of <LOQ.  

Water

For both the acute and chronic dietary exposure analyses, residues in
water were included directly in the analyses.  The Environmental Fate
and Effects Division (EFED) performed a drinking water assessment for
fenpropathrin (Memo, Jose Melendez, 9/03/2008).  EFED recommended that
no degradates be included in the risk assessment because of the low
levels at which they occurred in laboratory studies.  The EFED memo of
9/03/2008 provided Tier 1 estimated environmental concentrations for
fenpropathrin that were calculated using the FIRST Model for surface
water and the SCIGROW Model for groundwater.  For surface water, the
acute (peak) water concentration is 10.3 ppb, and the annual average
value is 1.8 ppb.  The groundwater screening concentration is 0.005 ppb.
 These values generally represent upper-bound estimates of the
concentrations that might be found in surface water and groundwater
resulting from the use of fenpropathrin on grapes, because this is the
scenario that results in the highest estimated drinking water
concentrations (EDWCs).  For the acute dietary exposure assessment, the
peak water concentration value of 10.3 ppb was used.  For the chronic
dietary exposure assessment, the annual average concentration of 1.8 ppb
was used.  

The model and its description are available at the EPA internet site:  
HYPERLINK "http://www.epa.gov/oppefed1/models/water/" 
http://www.epa.gov/oppefed1/models/water/ .  

Processing Factors

The registrant performed processing studies on some of the commodities
in the analysis.  Empirical processing factors were used for citrus,
grapes, melons, peanuts, apples, plums and tomatoes.  When empirical
processing factors were not available, default processing factors from
DEEM (Version 7.81) were used.  The DEEM default processing factors were
used for dried apples, dried apricots, dried beef, dried papaya, dried
peaches, dried pear, peanut butter, cherry juice, papaya juice, and plum
juice.  Table 1 below lists the empirical processing factors and the
DEEM 7.81 default processing factors that were used in the analyses.  

Processing factors from OPPTS 860.1520, Table 3 the Theoretical
Concentration Factors Based on Separation into Components were applied
to barley because of the absence of empirical processing data.  The
concentration factor for wheat flour was translated to barley flour.

Table 1:  Processing Factors for Fenpropathrin Dietary Risk Assessment

Commodity	

Process	

Factor	

Reference

Apple	

Juice	

0.04	

D257376

Apple	

Dried	

8.0	

DEEM 7.81 Default

Apricot	

Dried	

6.0	

DEEM 7.81 Default

Barley	

Bran	

7.7	

OPPTS 860.1520 - Table 3

Barley	

Pearled	

1.2	

OPPTS 860.1520 - Table 3

Barley	

Flour (translated from wheat) 	

1.4	

OPPTS 860.1520 - Table 3

Beef	

Dried	

1.92	

DEEM 7.81 Default

Cantaloupe	

Peeled	

0.02	

D257376

Cherry	

Juice	

1.5	

DEEM 7.81 Default

Citrus	

Juice	

0.06	

D257376

Citrus Peel	

	

2.6	

D257376

Grapes	

Raisins	

1.54	

D257376

Grapes	

Juice	

0.37	

D257376

Grapes	

Wine	

0.003	

D257376

Melons (except Watermelon)	

Peeling	

0.02	

D257376

Papaya 	

Dried	

1.8	

DEEM 7.81 Default

Papaya	

Juice	

1.5	

DEEM 7.81 Default

Peach	

Dried	

7.0	

DEEM 7.81 Default

Peanuts	

Refined Oil	

4.0	

D257376

Peanuts	

Peanut Butter	

1.89	

DEEM 7.81 Default

Pear	

Dried	

6.25	

DEEM 7.81 Default

Plum	

Juice	

1.4	

DEEM 7.81 Default

Plum	

Prune (Dried)	

2.6	

D333113

Tomatoes	

Washing	

0.83	

D257376

Tomatoes	

Juice	

0.05	

D257376

Tomatoes	

Paste	

0.3	

D257376

Tomatoes - Dried	

Washing x Drying	

0.83 x 14.3 = 11.87	

D257376 and DEEM 7.ㄸ܇

IV.	DEEM-FCID™ Program and Consumption Information

Fenpropathrin acute and chronic dietary exposure assessments were
conducted using the Dietary Exposure Evaluation Model software with the
Food Commodity Intake Database DEEM-FCID™, Version 2.03 which
incorporates consumption data from USDA’s Continuing Surveys of Food
Intakes by Individuals (CSFII), 1994-1996 and 1998.  The 1994-96, 98
data are based on the reported consumption of more than 20,000
individuals over two non-consecutive survey days.  Foods “as
consumed” (e.g., apple pie) are linked to EPA-defined food commodities
(e.g. apples, peeled fruit - cooked; fresh or N/S; baked; or wheat flour
- cooked; fresh or N/S, baked) using publicly available recipe
translation files developed jointly by USDA/ARS and EPA.  For chronic
exposure assessment, consumption data are averaged for the entire U.S.
population and within population subgroups, but for acute exposure
assessment are retained as individual consumption events.  Based on
analysis of the 1994-96, 98 CSFII consumption data, which took into
account dietary patterns and survey respondents, HED concluded that it
is most appropriate to report risk for the following population
subgroups: the general U.S. population, all infants (<1 year old),
children 1-2, children 3-5, children 6-12, youth 13-19, adults 20-49,
females 13-49, and adults 50+ years old.

For chronic dietary exposure assessment, an estimate of the residue
level in each food or food-form (e.g., orange or orange juice) on the
food commodity residue list is multiplied by the average daily
consumption estimate for that food/food form to produce a residue intake
estimate.  The resulting residue intake estimate for each food/food form
is summed with the residue intake estimates for all other food/food
forms on the commodity residue list to arrive at the total average
estimated exposure.  Exposure is expressed in mg/kg body weight/day and
as a percent of the cPAD.  This procedure is performed for each
population subgroup.

For acute exposure assessments, individual one-day food consumption data
are used on an individual-by-individual basis.  The reported consumption
amounts of each food item can be multiplied by a residue point estimate
and summed to obtain a total daily pesticide exposure for a
deterministic exposure assessment, or “matched” in multiple random
pairings with residue values and then summed in a probabilistic
assessment.  The resulting distribution of exposures is expressed as a
percentage of the aPAD on both a user (i.e., only those who reported
eating relevant commodities/food forms) and a per-capita (i.e., those
who reported eating the relevant commodities as well as those who did
not) basis.  In accordance with HED policy, per capita exposure and risk
are reported for all tiers of analysis.  However, for tiers 1 and 2, any
significant differences in user vs. per capita exposure and risk are
specifically identified and noted in the risk assessment.

V.	Toxicological Information

HED has evaluated the toxicology database for fenpropathrin.  The doses
and endpoints for dietary exposure assessment have been selected.  HED
has also assessed the need for an additional FQPA Safety Factor.  For a
detailed discussion of the toxicology and FQPA information and decisions
pertaining to fenpropathrin, please refer to the human health risk
assessment for which this dietary exposure assessment was prepared
(D313330, D. Dotson, 11/27/2008).  A summary of the doses and endpoints
is given in Table 2, below.

Table 2.  Toxicological Doses and Endpoints for Fenpropathrin 

Exposure/

Scenario	Point of Departure	Uncertainty/

FQPA Safety Factors	RfD, PAD, Level of Concern for Risk Assessment	Study
and Toxicological Effects

Acute Dietary (All populations)	NOAEL = 6.0 mg/kg/day

	UFA = 10X

UFH = 10X

FQPA SF = 1X 	Acute RfD = 6.0mg/kg/day

aPAD = 0.06 mg/kg/day

	Study: Rat Developmental Study

LOAEL = 10 mg/kg/day, based on clinical signs in maternal animals
including ataxia, sensitivity to stimuli, spastic jumping, and tremors
two hours post-dosing

Chronic Dietary (All Populations)	NOAEL = 2.5 mg/kg/day	UFA = 10X

UFH = 10X

FQPA SF = 1X	Chronic RfD = 2.5 mg/kg/day

cPAD = 0.025 mg/kg/day	Study: Chronic Dog Study

LOAEL =  6.25 mg/kg/day, based on tremors and ataxia beginning during
week 6 of testing

Cancer (oral, dermal, inhalation)	  SEQ CHAPTER \h \r 1 Classification:
“Not likely to be carcinogenic to humans”

Point of Departure (POD) = A data point or an estimated point that is
derived from observed dose-response data and  used to mark the beginning
of extrapolation to determine risk associated with lower environmentally
relevant human exposures.  NOAEL = no observed adverse effect level. 
LOAEL = lowest observed adverse effect level.  UF = uncertainty factor. 
UFA = extrapolation from animal to human (intraspecies).  UFH =
potential variation in sensitivity among members of the human population
(interspecies).  FQPA SF = FQPA Safety Factor.  PAD = population
adjusted dose (a = acute, c = chronic).  RfD = reference dose.  

VI.	Results/Discussion 

assessments, HED is concerned when dietary risk exceeds 100% of the PAD.
 The DEEM-FCID™ analyses estimate the dietary exposure of the U.S.
population and various population subgroups.  The results reported in
Table 3 are for the general U.S. Population, all infants (<1 year old),
children 1-2, children 3-5, children 6-12, youth 13-19, females 13-49,
adults 20-49, and adults 50+ years.  Cancer risk is determined for the
general U.S. population only.

Results of Acute Dietary Exposure Analysis (Food and Drinking Water)

The results of the acute dietary exposure analysis at the 95th
percentile of exposure are reported in Table 3.  The acute dietary risk
estimates for the general U.S. population and all population subgroups
are below HED’s level of concern.

Results of Chronic Dietary Exposure Analysis (Food and Drinking Water)

The results of the chronic dietary exposure analysis are reported in the
summary table below.  The chronic dietary risk estimates for the general
U.S. population and all population subgroups are below HED’s level of
concern.

 

Table 3.  Summary of Dietary Exposure and Risk for Fenpropathrin (Food
and Drinking Water)

Population Subgroup	Acute Dietary

(95th Percentile)	Chronic Dietary	Cancer

	Dietary Exposure (mg/kg/day)	% aPAD	Dietary Exposure

(mg/kg/day)	% cPAD	Dietary Exposure

(mg/kg/day)	Risk

General U.S. Population	0.012843	21	0.003622	14

All Infants (< 1 year old)	0.025763	43	0.005819	23	N/A	N/A

Children 1-2 years old	0.0317	53	0.010325	41

Children 3-5 years old	0.027571	46	0.008644	35

Children 6-12 years old	0.017509	29	0.00513	21

Youth 13-19 years old	0.008862	15	0.002572	10

Adults 20-49 years old	0.009329	16	0.002644	11

Adults 50+ years old	0.010777	18	0.003265	13

Females 13-49 years old	0.009325	16	0.002678	11

VII.	Characterization of Inputs/Outputs

Tolerance level residues and field trial data were used for the various
commodities in the analyses.  Field trial data were only used for
apples, cherries, grapes, peaches, pears, and plums.  Tolerance level
residues were used for all other registered commodities as well as for
the proposed commodities.  As a result, HED considers these analyses to
be refined, but not highly refined.  Further refinement to the analysis
could be made through the use of additional anticipated residues,
incorporation of percentages of crops treated with fenpropathrin, and/or
monitoring data that better reflect residues at the time of consumption.
 Since risk estimates are well below HED’s level of concern, a more
highly refined analysis is not needed at this time.

VIII.	Conclusions

Acute and chronic dietary exposure analyses were performed for
fenpropathrin.  The analyses were based on crop field trial data,
processing factors, and 100% percent crop treated.  HED considers these
analyses to be refined, but not highly refined.  In both the acute and
chronic analyses, the general U.S. population and all population
subgroups have risk estimates that are below HED’s level of concern. 
In the acute analysis, the most highly exposed subgroup Children (1-2)
utilizes 53% of the aPAD.  The general U.S. population utilizes 21% of
the aPAD.  In the chronic analysis, the most highly exposed subgroup,
Children (1-2) utilizes 41% of the cPAD.  The general U.S. population
utilizes 14% of the cPAD.

IX.		List of Attachments

Attachment 1: Residue Input File for Acute Analysis

Attachment 2: Results of Acute Dietary Exposure Analysis

Attachment 3: Residue Input File for Chronic Analysis

Attachment 4: Results of Chronic Dietary Exposure Analysis

Attachment 5: Field Trial Values for Proposed Commodities

Attachment 6: RDF Files

Attachment 1: Residue Input File for Acute Analysis

U.S. Environmental Protection Agency                                
Ver. 2.02

DEEM-FCID Acute analysis for FENPROPATHRIN

Residue file name: C:\Documents and
Settings\aparmar\Desktop\Fenpropathrin DA\v3.1 (Final)\v3.1 Acute
R98.R98

Analysis Date 10-14-2008             Residue file dated:
10-14-2008/09:36:12/8

Reference dose: aRfD = 0.06 mg/kg bw/day  NOEL = 6 mg/kg bw/day

Comment: APAD 0.06 mg/kg - no PCT, Tolerance and FT Data,

------------------------------------------------------------------------
--------

RDL indices and parameters for Monte Carlo Analysis:

Index Dist Parameter #1           Param #2    Param #3    Comment

  #   Code 

----- ---- ------------           ----------- ----------- ----------

  1    6   Apple FT.RDF

  2    6   Pear FT.RDF

  3    6   Grape FT.RDF

  4    6   Cherry FT.RDF

  5    6   Peach FT.RDF

  6    6   Plum FT.RDF

  EPA    Crop Food Name                         Def Res     Adj.Factors 
RDL  Comment

  Code    Grp                                    (ppm)       #1     #2  
Pntr

-------- ---- -------------------------------  ----------  ------ ------
---  -------

14000030 14   Almond                             0.100000   1.000  1.000
     

14000031 14   Almond-babyfood                    0.100000   1.000  1.000
     

14000040 14   Almond, oil                        0.100000   1.000  1.000
     

14000041 14   Almond, oil-babyfood               0.100000   1.000  1.000
     

11000070 11   Apple, fruit with peel             5.000000   1.000  1.000
  1  FT

11000080 11   Apple, peeled fruit                5.000000   1.000  1.000
  1  FT

11000081 11   Apple, peeled fruit-babyfood       5.000000   1.000  1.000
  1  FT

11000090 11   Apple, dried                       0.770000   8.000  1.000
     FT

11000091 11   Apple, dried-babyfood              0.770000   8.000  1.000
     FT

11000100 11   Apple, juice                       5.000000   0.040  1.000
  1  FT

11000101 11   Apple, juice-babyfood              5.000000   0.040  1.000
  1  FT

11000110 11   Apple, sauce                       5.000000   1.000  1.000
  1  FT

11000111 11   Apple, sauce-babyfood              5.000000   1.000  1.000
  1  FT

12000120 12   Apricot                            1.400000   1.000  1.000
  5  FT

12000121 12   Apricot-babyfood                   1.400000   1.000  1.000
  5  FT

12000130 12   Apricot, dried                     0.740000   6.000  1.000
     FT

12000140 12   Apricot, juice                     1.400000   1.000  1.000
  5  FT

12000141 12   Apricot, juice-babyfood            1.400000   1.000  1.000
  5  FT

95000200 O    Avocado                            1.000000   1.000  1.000
     

09020210 9B   Balsam pear                        0.500000   1.000  1.000
     

15000250 15   Barley, pearled barley             0.040000   1.200  1.000
     Tol T.

    Full comment: Tol T.PF

15000251 15   Barley, pearled barley-babyfood    0.040000   1.200  1.000
     Tol T.

    Full comment: Tol T.PF

15000260 15   Barley, flour                      0.040000   1.400  1.000
     Tol T.

    Full comment: Tol T.PF

15000261 15   Barley, flour-babyfood             0.040000   1.400  1.000
     Tol T.

    Full comment: Tol T.PF

15000270 15   Barley, bran                       0.040000   7.700  1.000
     Tol T.

    Full comment: Tol T.PF

21000440 M    Beef, meat                         0.010000   1.000  1.000
     

21000441 M    Beef, meat-babyfood                0.010000   1.000  1.000
     

21000450 M    Beef, meat, dried                  0.010000   1.920  1.000
     

21000460 M    Beef, meat byproducts              0.010000   1.000  1.000
     

21000461 M    Beef, meat byproducts-babyfood     0.010000   1.000  1.000
     

21000470 M    Beef, fat                          0.050000   1.000  1.000
     

21000471 M    Beef,fat-babyfood                  0.050000   1.000  1.000
     

21000480 M    Beef, kidney                       0.010000   1.000  1.000
     

21000490 M    Beef, liver                        0.010000   1.000  1.000
     

21000491 M    Beef, liver-babyfood               0.010000   1.000  1.000
     

13010550 13A  Blackberry                        12.000000   1.000  1.000
     

13010560 13A  Blackberry, juice                 12.000000   1.000  1.000
     

13010561 13A  Blackberry, juice-babyfood        12.000000   1.000  1.000
     

13020570 13B  Blueberry                          3.000000   1.000  1.000
     

13020571 13B  Blueberry-babyfood                 3.000000   1.000  1.000
     

13010580 13A  Boysenberry                       12.000000   1.000  1.000
     

14000590 14   Brazil nut                         0.100000   1.000  1.000
     

05010610 5A   Broccoli                           3.000000   1.000  1.000
     

05010611 5A   Broccoli-babyfood                  3.000000   1.000  1.000
     

05010620 5A   Broccoli, Chinese                  3.000000   1.000  1.000
     

05010640 5A   Brussels sprouts                   3.000000   1.000  1.000
     

14000680 14   Butternut                          0.100000   1.000  1.000
     

05010690 5A   Cabbage                            3.000000   1.000  1.000
     

05010710 5A   Cabbage, Chinese, napa             3.000000   1.000  1.000
     

05010720 5A   Cabbage, Chinese, mustard          3.000000   1.000  1.000
     

95000740 O    Canistel                           1.000000   1.000  1.000
     

09010750 9A   Cantaloupe                         0.500000   0.020  1.000
     

09010800 9A   Casaba                             0.500000   0.020  1.000
     

14000810 14   Cashew                             0.100000   1.000  1.000
     

05010830 5A   Cauliflower                        3.000000   1.000  1.000
     

09020880 9B   Chayote, fruit                     0.500000   1.000  1.000
     

12000900 12   Cherry                             5.000000   1.000  1.000
  4  FT

12000901 12   Cherry-babyfood                    5.000000   1.000  1.000
  4  FT

12000910 12   Cherry, juice                      5.000000   1.500  1.000
  4  FT

12000911 12   Cherry, juice-babyfood             5.000000   1.500  1.000
  4  FT

14000920 14   Chestnut                           0.100000   1.000  1.000
     

40000930 P    Chicken, meat                      0.050000   1.000  1.000
     

40000931 P    Chicken, meat-babyfood             0.050000   1.000  1.000
     

40000940 P    Chicken, liver                     0.050000   1.000  1.000
     

40000950 P    Chicken, meat byproducts           0.050000   1.000  1.000
     

40000951 P    Chicken, meat byproducts-babyfoo   0.050000   1.000  1.000
     

40000960 P    Chicken, fat                       0.050000   1.000  1.000
     

40000961 P    Chicken, fat-babyfood              0.050000   1.000  1.000
     

40000970 P    Chicken, skin                      0.050000   1.000  1.000
     

40000971 P    Chicken, skin-babyfood             0.050000   1.000  1.000
     

09021020 9B   Chinese waxgourd                   0.500000   1.000  1.000
     

10001060 10   Citrus citron                      2.000000   1.000  1.000
     

10001070 10   Citrus hybrids                     2.000000   1.000  1.000
     

10001080 10   Citrus, oil                       75.000000   1.000  1.000
     

95001280 O    Cottonseed, oil                    3.000000   1.000  1.000
     

95001281 O    Cottonseed, oil-babyfood           3.000000   1.000  1.000
     

11001290 11   Crabapple                          5.000000   1.000  1.000
     TOL

09021350 9B   Cucumber                           0.500000   1.000  1.000
     

13021360 13B  Currant                           15.000000   1.000  1.000
     

13021370 13B  Currant, dried                    15.000000   1.000  1.000
     

13011420 13A  Dewberry                          12.000000   1.000  1.000
     

70001450 P    Egg, whole                         0.050000   1.000  1.000
     

70001451 P    Egg, whole-babyfood                0.050000   1.000  1.000
     

70001460 P    Egg, white                         0.050000   1.000  1.000
     

70001461 P    Egg, white (solids)-babyfood       0.050000   1.000  1.000
     

70001470 P    Egg, yolk                          0.050000   1.000  1.000
     

70001471 P    Egg, yolk-babyfood                 0.050000   1.000  1.000
     

08001480 8    Eggplant                           1.000000   1.000  1.000
     

13021490 13B  Elderberry                         3.000000   1.000  1.000
     

14001550 14   Filbert                            0.100000   1.000  1.000
     

14001560 14   Filbert, oil                       0.100000   1.000  1.000
     

23001690 M    Goat, meat                         0.010000   1.000  1.000
     

23001700 M    Goat, meat byproducts              0.010000   1.000  1.000
     

23001710 M    Goat, fat                          0.050000   1.000  1.000
     

23001720 M    Goat, kidney                       0.010000   1.000  1.000
     

23001730 M    Goat, liver                        0.010000   1.000  1.000
     

13021740 13B  Gooseberry                         3.000000   1.000  1.000
     

95001750 O    Grape                              5.000000   1.000  1.000
  3  FT

95001760 O    Grape, juice                       5.000000   0.370  1.000
  3  FT

95001761 O    Grape, juice-babyfood              5.000000   0.370  1.000
  3  FT

95001770 O    Grape, leaves                      5.000000   1.000  1.000
  3  FT

95001780 O    Grape, raisin                      5.000000   1.540  1.000
  3  FT

95001790 O    Grape, wine and sherry             5.000000   0.003  1.000
  3  FT

10001800 10   Grapefruit                         2.000000   1.000  1.000
     

10001810 10   Grapefruit, juice                  2.000000   0.060  1.000
     

14001850 14   Hickory nut                        0.100000   1.000  1.000
     

09011870 9A   Honeydew melon                     0.500000   0.020  1.000
     

24001890 M    Horse, meat                        0.010000   1.000  1.000
     

13021910 13B  Huckleberry                        3.000000   1.000  1.000
     

05011960 5A   Kohlrabi                           3.000000   1.000  1.000
     

10001970 10   Kumquat                            2.000000   1.000  1.000
     

10001990 10   Lemon                              2.000000   1.000  1.000
     

10002000 10   Lemon, juice                       2.000000   0.060  1.000
     

10002001 10   Lemon, juice-babyfood              2.000000   0.060  1.000
     

10002010 10   Lemon, peel                        2.000000   2.600  1.000
     

10002060 10   Lime                               2.000000   1.000  1.000
     

10002070 10   Lime, juice                        2.000000   0.060  1.000
     

10002071 10   Lime, juice-babyfood               2.000000   0.060  1.000
     

13012080 13A  Loganberry                        12.000000   1.000  1.000
     

11002100 11   Loquat                             5.000000   1.000  1.000
     TOL

14002130 14   Macadamia nut                      0.100000   1.000  1.000
     

95002150 O    Mango                              1.000000   1.000  1.000
     

95002151 O    Mango-babyfood                     1.000000   1.000  1.000
     

95002160 O    Mango, dried                       1.000000   1.000  1.000
     

95002170 O    Mango, juice                       1.000000   1.000  1.000
     

95002171 O    Mango, juice-babyfood              1.000000   1.000  1.000
     

28002210 M    Meat, game                         0.010000   1.000  1.000
     

27002220 D    Milk, fat                          0.050000   1.000  1.000
     

27002221 D    Milk, fat - baby food/infant for   0.050000   1.000  1.000
     

12002300 12   Nectarine                          1.400000   1.000  1.000
  5  FT

08002340 8    Okra                               1.000000   1.000  1.000
     

95002350 O    Olive                              5.000000   1.000  1.000
     

10002400 10   Orange                             2.000000   1.000  1.000
     

10002410 10   Orange, juice                      2.000000   0.060  1.000
     

10002411 10   Orange, juice-babyfood             2.000000   0.060  1.000
     

10002420 10   Orange, peel                       2.000000   2.600  1.000
     

95002450 O    Papaya                             1.000000   1.000  1.000
     

95002451 O    Papaya-babyfood                    1.000000   1.000  1.000
     

95002460 O    Papaya, dried                      1.000000   1.800  1.000
     

95002470 O    Papaya, juice                      1.000000   1.500  1.000
     

06022550 6B   Pea, succulent                     0.020000   1.000  1.000
     

06022551 6B   Pea, succulent-babyfood            0.020000   1.000  1.000
     

06012570 6A   Pea, edible podded, succulent      0.020000   1.000  1.000
     

06022590 6B   Pea, pigeon, succulent             0.020000   1.000  1.000
     

12002600 12   Peach                              1.400000   1.000  1.000
  5  FT

12002601 12   Peach-babyfood                     1.400000   1.000  1.000
  5  FT

12002610 12   Peach, dried                       0.740000   7.000  1.000
     FT

12002611 12   Peach, dried-babyfood              0.740000   7.000  1.000
     FT

12002620 12   Peach, juice                       1.400000   1.000  1.000
  5  FT

12002621 12   Peach, juice-babyfood              1.400000   1.000  1.000
  5  FT

95002630 O    Peanut                             0.010000   1.000  1.000
     

95002640 O    Peanut, butter                     0.010000   1.890  1.000
     

95002650 O    Peanut, oil                        0.010000   4.000  1.000
     

11002660 11   Pear                               5.000000   1.000  1.000
  2  FT

11002661 11   Pear-babyfood                      5.000000   1.000  1.000
  2  FT

11002670 11   Pear, dried                        0.880000   6.250  1.000
     FT

11002680 11   Pear, juice                        5.000000   1.000  1.000
  2  FT

11002681 11   Pear, juice-babyfood               5.000000   1.000  1.000
  2  FT

14002690 14   Pecan                              0.100000   1.000  1.000
     

08002700 8    Pepper, bell                       1.000000   1.000  1.000
     

08002701 8    Pepper, bell-babyfood              1.000000   1.000  1.000
     

08002710 8    Pepper, bell, dried                1.000000   1.000  1.000
     

08002711 8    Pepper, bell, dried-babyfood       1.000000   1.000  1.000
     

08002720 8    Pepper, nonbell                    1.000000   1.000  1.000
     

08002721 8    Pepper, nonbell-babyfood           1.000000   1.000  1.000
     

08002730 8    Pepper, nonbell, dried             1.000000   1.000  1.000
     

14002820 14   Pistachio                          0.100000   1.000  1.000
     

12002850 12   Plum                               1.400000   1.000  1.000
  6  FT

12002851 12   Plum-babyfood                      1.400000   1.000  1.000
  6  FT

12002860 12   Plum, prune, fresh                 1.400000   1.000  1.000
  6  FT

12002861 12   Plum, prune, fresh-babyfood        1.400000   1.000  1.000
  6  FT

12002870 12   Plum, prune, dried                 1.400000   2.600  1.000
  6  FT E.P

    Full comment: FT E.PF

12002871 12   Plum, prune, dried-babyfood        1.400000   2.600  1.000
  6  FT E.P

    Full comment: FT E.PF

12002880 12   Plum, prune, juice                 1.400000   1.400  1.000
  6  FT

12002881 12   Plum, prune, juice-babyfood        1.400000   1.400  1.000
  6  FT

60003010 P    Poultry, other, meat               0.050000   1.000  1.000
     

60003020 P    Poultry, other, liver              0.050000   1.000  1.000
     

60003030 P    Poultry, other, meat byproducts    0.050000   1.000  1.000
     

60003040 P    Poultry, other, fat                0.050000   1.000  1.000
     

60003050 P    Poultry, other, skin               0.050000   1.000  1.000
     

10003070 10   Pummelo                            2.000000   1.000  1.000
     

09023080 9B   Pumpkin                            0.500000   1.000  1.000
     

09023090 9B   Pumpkin, seed                      0.500000   1.000  1.000
     

11003100 11   Quince                             5.000000   1.000  1.000
     TOL

29003120 M    Rabbit, meat                       0.010000   1.000  1.000
     

13013200 13A  Raspberry                         12.000000   1.000  1.000
     

13013201 13A  Raspberry-babyfood                12.000000   1.000  1.000
     

13013210 13A  Raspberry, juice                  12.000000   1.000  1.000
     

13013211 13A  Raspberry, juice-babyfood         12.000000   1.000  1.000
     

95003330 O    Sapote, Mamey                      1.000000   1.000  1.000
     

26003390 M    Sheep, meat                        0.010000   1.000  1.000
     

26003391 M    Sheep, meat-babyfood               0.010000   1.000  1.000
     

26003400 M    Sheep, meat byproducts             0.010000   1.000  1.000
     

26003410 M    Sheep, fat                         0.050000   1.000  1.000
     

26003411 M    Sheep, fat-babyfood                0.050000   1.000  1.000
     

26003420 M    Sheep, kidney                      0.010000   1.000  1.000
     

26003430 M    Sheep, liver                       0.010000   1.000  1.000
     

09023560 9B   Squash, summer                     0.500000   1.000  1.000
     

09023561 9B   Squash, summer-babyfood            0.500000   1.000  1.000
     

09023570 9B   Squash, winter                     0.500000   1.000  1.000
     

09023571 9B   Squash, winter-babyfood            0.500000   1.000  1.000
     

95003590 O    Strawberry                         2.000000   1.000  1.000
     

95003591 O    Strawberry-babyfood                2.000000   1.000  1.000
     

95003600 O    Strawberry, juice                  2.000000   1.000  1.000
     

95003601 O    Strawberry, juice-babyfood         2.000000   1.000  1.000
     

10003690 10   Tangerine                          2.000000   1.000  1.000
     

10003700 10   Tangerine, juice                   2.000000   0.060  1.000
     

08003740 8    Tomatillo                          1.000000   1.000  1.000
     

08003750 8    Tomato                             1.000000   0.830  1.000
     

08003751 8    Tomato-babyfood                    1.000000   0.830  1.000
     

08003760 8    Tomato, paste                      1.000000   0.300  1.000
     

08003761 8    Tomato, paste-babyfood             1.000000   0.300  1.000
     

08003770 8    Tomato, puree                      1.000000   0.830  1.000
     

08003771 8    Tomato, puree-babyfood             1.000000   0.830  1.000
     

08003780 8    Tomato, dried                      1.000000  11.870  1.000
     

08003781 8    Tomato, dried-babyfood             1.000000  11.870  1.000
     

08003790 8    Tomato, juice                      1.000000   0.050  1.000
     

50003820 P    Turkey, meat                       0.050000   1.000  1.000
     

50003821 P    Turkey, meat-babyfood              0.050000   1.000  1.000
     

50003830 P    Turkey, liver                      0.050000   1.000  1.000
     

50003831 P    Turkey, liver-babyfood             0.050000   1.000  1.000
     

50003840 P    Turkey, meat byproducts            0.050000   1.000  1.000
     

50003841 P    Turkey, meat byproducts-babyfood   0.050000   1.000  1.000
     

50003850 P    Turkey, fat                        0.050000   1.000  1.000
     

50003851 P    Turkey, fat-babyfood               0.050000   1.000  1.000
     

50003860 P    Turkey, skin                       0.050000   1.000  1.000
     

50003861 P    Turkey, skin-babyfood              0.050000   1.000  1.000
     

14003910 14   Walnut                             0.100000   1.000  1.000
     

86010000 O    Water, direct, all sources         0.010300   1.000  1.000
     

86020000 O    Water, indirect, all sources       0.010300   1.000  1.000
     

09013990 9A   Watermelon                         0.500000   1.000  1.000
     

09014000 9A   Watermelon, juice                  0.500000   1.000  1.000
     

Attachment 2: Results of Acute Dietary Exposure Analysis

U.S. Environmental Protection Agency                                 
Ver. 2.02

DEEM-FCID ACUTE Analysis for FENPROPATHRIN                      
(1994-98 data)

Residue file: v3.1 Acute R98.R98                  Adjustment factor #2
NOT used.

Analysis Date: 10-14-2008/09:43:25    Residue file dated:
10-14-2008/09:36:12/8

NOEL (Acute) =   6.000000 mg/kg body-wt/day

Daily totals for food and foodform consumption used.

MC iterations = 1000      MC list in residue file     MC seed = 1

Run Comment: "APAD 0.06 mg/kg - no PCT, Tolerance and FT Data, "

========================================================================
=======

Summary calculations (per capita):

      95th Percentile             99th Percentile             99.9th
Percentile

 Exposure  % aRfD     MOE    Exposure  % aRfD     MOE    Exposure  %
aRfD     MOE  

---------- ------- -------- ---------- ------- -------- ----------
------- --------

U.S. Population:

  0.012843   21.41     467    0.025882   43.14     231    0.052860  
88.10     113  

All infants:

  0.025763   42.94     232    0.044311   73.85     135    0.069495 
115.83      86  

Children 1-2 yrs:

  0.031700   52.83     189    0.056224   93.71     106    0.093661 
156.10      64  

Children 3-5 yrs:

  0.027571   45.95     217    0.046513   77.52     128    0.080624 
134.37      74  

Children 6-12 yrs:

  0.017509   29.18     342    0.032689   54.48     183    0.069101 
115.17      86  

Youth 13-19 yrs:

  0.008862   14.77     677    0.017290   28.82     347    0.049255  
82.09     121  

Adults 20-49 yrs:

  0.009329   15.55     643    0.016525   27.54     363    0.033185  
55.31     180  

Adults 50+ yrs:

  0.010777   17.96     556    0.018609   31.02     322    0.034341  
57.24     174  

Females 13-49 yrs:

  0.009325   15.54     643    0.016640   27.73     360    0.034810  
58.02     172  

Attachment 3: Residue Input File for Chronic Analysis

U.S. Environmental Protection Agency                                
Ver. 2.00

DEEM-FCID Chronic analysis for FENPROPATHRIN                     
1994-98 data

Residue file: C:\Documents and Settings\aparmar\Desktop\Fenpropathrin
DA\v3.1 (Final)\v3.1 Chronic R98.R98

                                                           Adjust. #2
NOT used

Analysis Date 10-14-2008             Residue file dated:
10-14-2008/09:31:58/8

Reference dose (RfD) = 0.025 mg/kg bw/day

Comment:CPAD 0.025 mg/kg - no PCT, Tolerance and FT Data

------------------------------------------------------------------------
--------

Food Crop                                       Residue      
Adj.Factors      Comment

EPA Code  Grp  Food Name                          (ppm)       

                                                             #1        
#2 

-------- ---- -------------------------------   ---------- ------    
------   -------

14000030 14   Almond                             0.100000   1.000     
1.000   

14000031 14   Almond-babyfood                    0.100000   1.000     
1.000   

14000040 14   Almond, oil                        0.100000   1.000     
1.000   

14000041 14   Almond, oil-babyfood               0.100000   1.000     
1.000   

11000070 11   Apple, fruit with peel             0.770000   1.000     
1.000   FT

11000080 11   Apple, peeled fruit                0.770000   1.000     
1.000   FT

11000081 11   Apple, peeled fruit-babyfood       0.770000   1.000     
1.000   FT

11000090 11   Apple, dried                       0.770000   8.000     
1.000   FT

11000091 11   Apple, dried-babyfood              0.770000   8.000     
1.000   FT

11000100 11   Apple, juice                       0.770000   0.040     
1.000   FT

11000101 11   Apple, juice-babyfood              0.770000   0.040     
1.000   FT

11000110 11   Apple, sauce                       0.770000   1.000     
1.000   FT

11000111 11   Apple, sauce-babyfood              0.770000   1.000     
1.000   FT

12000120 12   Apricot                            0.740000   1.000     
1.000   FT

12000121 12   Apricot-babyfood                   0.740000   1.000     
1.000   FT

12000130 12   Apricot, dried                     0.740000   6.000     
1.000   FT

12000140 12   Apricot, juice                     0.740000   1.000     
1.000   FT

12000141 12   Apricot, juice-babyfood            0.740000   1.000     
1.000   FT

95000200 O    Avocado                            1.000000   1.000     
1.000   

09020210 9B   Balsam pear                        0.500000   1.000     
1.000   

15000250 15   Barley, pearled barley             0.040000   1.200     
1.000   TOL T.

  Full comment: TOL T.PF

15000251 15   Barley, pearled barley-babyfood    0.040000   1.200     
1.000   TOL T.

  Full comment: TOL T.PF

15000260 15   Barley, flour                      0.040000   1.400     
1.000   TOL T.

  Full comment: TOL T.PF

15000261 15   Barley, flour-babyfood             0.040000   1.400     
1.000   TOL T.

  Full comment: TOL T.PF

15000270 15   Barley, bran                       0.040000   7.700     
1.000   TOL T.

  Full comment: TOL T.PF

21000440 M    Beef, meat                         0.010000   1.000     
1.000   

21000441 M    Beef, meat-babyfood                0.010000   1.000     
1.000   

21000450 M    Beef, meat, dried                  0.010000   1.920     
1.000   

21000460 M    Beef, meat byproducts              0.010000   1.000     
1.000   

21000461 M    Beef, meat byproducts-babyfood     0.010000   1.000     
1.000   

21000470 M    Beef, fat                          0.050000   1.000     
1.000   

21000471 M    Beef,fat-babyfood                  0.050000   1.000     
1.000   

21000480 M    Beef, kidney                       0.010000   1.000     
1.000   

21000490 M    Beef, liver                        0.010000   1.000     
1.000   

21000491 M    Beef, liver-babyfood               0.010000   1.000     
1.000   

13010550 13A  Blackberry                        12.000000   1.000     
1.000   

13010560 13A  Blackberry, juice                 12.000000   1.000     
1.000   

13010561 13A  Blackberry, juice-babyfood        12.000000   1.000     
1.000   

13020570 13B  Blueberry                          3.000000   1.000     
1.000   

13020571 13B  Blueberry-babyfood                 3.000000   1.000     
1.000   

13010580 13A  Boysenberry                       12.000000   1.000     
1.000   

14000590 14   Brazil nut                         0.100000   1.000     
1.000   

05010610 5A   Broccoli                           3.000000   1.000     
1.000   

05010611 5A   Broccoli-babyfood                  3.000000   1.000     
1.000   

05010620 5A   Broccoli, Chinese                  3.000000   1.000     
1.000   

05010640 5A   Brussels sprouts                   3.000000   1.000     
1.000   

14000680 14   Butternut                          0.100000   1.000     
1.000   

05010690 5A   Cabbage                            3.000000   1.000     
1.000   

05010710 5A   Cabbage, Chinese, napa             3.000000   1.000     
1.000   

05010720 5A   Cabbage, Chinese, mustard          3.000000   1.000     
1.000   

95000740 O    Canistel                           1.000000   1.000     
1.000   

09010750 9A   Cantaloupe                         0.500000   0.020     
1.000   

09010800 9A   Casaba                             0.500000   0.020     
1.000   

14000810 14   Cashew                             0.100000   1.000     
1.000   

05010830 5A   Cauliflower                        3.000000   1.000     
1.000   

09020880 9B   Chayote, fruit                     0.500000   1.000     
1.000   

12000900 12   Cherry                             2.220000   1.000     
1.000   FT

12000901 12   Cherry-babyfood                    2.220000   1.000     
1.000   FT

12000910 12   Cherry, juice                      2.220000   1.500     
1.000   FT

12000911 12   Cherry, juice-babyfood             2.220000   1.500     
1.000   FT

14000920 14   Chestnut                           0.100000   1.000     
1.000   

40000930 P    Chicken, meat                      0.050000   1.000     
1.000   

40000931 P    Chicken, meat-babyfood             0.050000   1.000     
1.000   

40000940 P    Chicken, liver                     0.050000   1.000     
1.000   

40000950 P    Chicken, meat byproducts           0.050000   1.000     
1.000   

40000951 P    Chicken, meat byproducts-babyfoo   0.050000   1.000     
1.000   

40000960 P    Chicken, fat                       0.050000   1.000     
1.000   

40000961 P    Chicken, fat-babyfood              0.050000   1.000     
1.000   

40000970 P    Chicken, skin                      0.050000   1.000     
1.000   

40000971 P    Chicken, skin-babyfood             0.050000   1.000     
1.000   

09021020 9B   Chinese waxgourd                   0.500000   1.000     
1.000   

10001060 10   Citrus citron                      2.000000   1.000     
1.000   

10001070 10   Citrus hybrids                     2.000000   1.000     
1.000   

10001080 10   Citrus, oil                       75.000000   1.000     
1.000   

95001280 O    Cottonseed, oil                    3.000000   1.000     
1.000   

95001281 O    Cottonseed, oil-babyfood           3.000000   1.000     
1.000   

11001290 11   Crabapple                          5.000000   1.000     
1.000   TOL

09021350 9B   Cucumber                           0.500000   1.000     
1.000   

13021360 13B  Currant                           15.000000   1.000     
1.000   

13021370 13B  Currant, dried                    15.000000   1.000     
1.000   

13011420 13A  Dewberry                          12.000000   1.000     
1.000   

70001450 P    Egg, whole                         0.050000   1.000     
1.000   

70001451 P    Egg, whole-babyfood                0.050000   1.000     
1.000   

70001460 P    Egg, white                         0.050000   1.000     
1.000   

70001461 P    Egg, white (solids)-babyfood       0.050000   1.000     
1.000   

70001470 P    Egg, yolk                          0.050000   1.000     
1.000   

70001471 P    Egg, yolk-babyfood                 0.050000   1.000     
1.000   

08001480 8    Eggplant                           1.000000   1.000     
1.000   

13021490 13B  Elderberry                         3.000000   1.000     
1.000   

14001550 14   Filbert                            0.100000   1.000     
1.000   

14001560 14   Filbert, oil                       0.100000   1.000     
1.000   

23001690 M    Goat, meat                         0.010000   1.000     
1.000   

23001700 M    Goat, meat byproducts              0.010000   1.000     
1.000   

23001710 M    Goat, fat                          0.050000   1.000     
1.000   

23001720 M    Goat, kidney                       0.010000   1.000     
1.000   

23001730 M    Goat, liver                        0.010000   1.000     
1.000   

13021740 13B  Gooseberry                         3.000000   1.000     
1.000   

95001750 O    Grape                              1.120000   1.000     
1.000   FT

95001760 O    Grape, juice                       1.120000   0.370     
1.000   FT

95001761 O    Grape, juice-babyfood              1.120000   0.370     
1.000   FT

95001770 O    Grape, leaves                      1.120000   1.000     
1.000   FT

95001780 O    Grape, raisin                      1.120000   1.540     
1.000   FT

95001790 O    Grape, wine and sherry             1.120000   0.003     
1.000   FT

10001800 10   Grapefruit                         2.000000   1.000     
1.000   

10001810 10   Grapefruit, juice                  2.000000   0.060     
1.000   

14001850 14   Hickory nut                        0.100000   1.000     
1.000   

09011870 9A   Honeydew melon                     0.500000   0.020     
1.000   

24001890 M    Horse, meat                        0.010000   1.000     
1.000   

13021910 13B  Huckleberry                        3.000000   1.000     
1.000   

05011960 5A   Kohlrabi                           3.000000   1.000     
1.000   

10001970 10   Kumquat                            2.000000   1.000     
1.000   

10001990 10   Lemon                              2.000000   1.000     
1.000   

10002000 10   Lemon, juice                       2.000000   0.060     
1.000   

10002001 10   Lemon, juice-babyfood              2.000000   0.060     
1.000   

10002010 10   Lemon, peel                        2.000000   2.600     
1.000   

10002060 10   Lime                               2.000000   1.000     
1.000   

10002070 10   Lime, juice                        2.000000   0.060     
1.000   

10002071 10   Lime, juice-babyfood               2.000000   0.060     
1.000   

13012080 13A  Loganberry                        12.000000   1.000     
1.000   

11002100 11   Loquat                             5.000000   1.000     
1.000   TOL

14002130 14   Macadamia nut                      0.100000   1.000     
1.000   

95002150 O    Mango                              1.000000   1.000     
1.000   

95002151 O    Mango-babyfood                     1.000000   1.000     
1.000   

95002160 O    Mango, dried                       1.000000   1.000     
1.000   

95002170 O    Mango, juice                       1.000000   1.000     
1.000   

95002171 O    Mango, juice-babyfood              1.000000   1.000     
1.000   

28002210 M    Meat, game                         0.010000   1.000     
1.000   

27002220 D    Milk, fat                          0.050000   1.000     
1.000   

27002221 D    Milk, fat - baby food/infant for   0.050000   1.000     
1.000   

12002300 12   Nectarine                          0.740000   1.000     
1.000   FT

08002340 8    Okra                               1.000000   1.000     
1.000   

95002350 O    Olive                              5.000000   1.000     
1.000   

10002400 10   Orange                             2.000000   1.000     
1.000   

10002410 10   Orange, juice                      2.000000   0.060     
1.000   

10002411 10   Orange, juice-babyfood             2.000000   0.060     
1.000   

10002420 10   Orange, peel                       2.000000   2.600     
1.000   

95002450 O    Papaya                             1.000000   1.000     
1.000   

95002451 O    Papaya-babyfood                    1.000000   1.000     
1.000   

95002460 O    Papaya, dried                      1.000000   1.800     
1.000   

95002470 O    Papaya, juice                      1.000000   1.500     
1.000   

06022550 6B   Pea, succulent                     0.020000   1.000     
1.000   

06022551 6B   Pea, succulent-babyfood            0.020000   1.000     
1.000   

06012570 6A   Pea, edible podded, succulent      0.020000   1.000     
1.000   

06022590 6B   Pea, pigeon, succulent             0.020000   1.000     
1.000   

12002600 12   Peach                              0.740000   1.000     
1.000   FT

12002601 12   Peach-babyfood                     0.740000   1.000     
1.000   FT

12002610 12   Peach, dried                       0.740000   7.000     
1.000   FT

12002611 12   Peach, dried-babyfood              0.740000   7.000     
1.000   FT

12002620 12   Peach, juice                       0.740000   1.000     
1.000   FT

12002621 12   Peach, juice-babyfood              0.740000   1.000     
1.000   FT

95002630 O    Peanut                             0.010000   1.000     
1.000   

95002640 O    Peanut, butter                     0.010000   1.890     
1.000   

95002650 O    Peanut, oil                        0.010000   4.000     
1.000   

11002660 11   Pear                               0.880000   1.000     
1.000   FT

11002661 11   Pear-babyfood                      0.880000   1.000     
1.000   FT

11002670 11   Pear, dried                        0.880000   6.250     
1.000   FT

11002680 11   Pear, juice                        0.880000   1.000     
1.000   FT

11002681 11   Pear, juice-babyfood               0.880000   1.000     
1.000   FT

14002690 14   Pecan                              0.100000   1.000     
1.000   

08002700 8    Pepper, bell                       1.000000   1.000     
1.000   

08002701 8    Pepper, bell-babyfood              1.000000   1.000     
1.000   

08002710 8    Pepper, bell, dried                1.000000   1.000     
1.000   

08002711 8    Pepper, bell, dried-babyfood       1.000000   1.000     
1.000   

08002720 8    Pepper, nonbell                    1.000000   1.000     
1.000   

08002721 8    Pepper, nonbell-babyfood           1.000000   1.000     
1.000   

08002730 8    Pepper, nonbell, dried             1.000000   1.000     
1.000   

14002820 14   Pistachio                          0.100000   1.000     
1.000   

12002850 12   Plum                               0.300000   1.000     
1.000   FT

12002851 12   Plum-babyfood                      0.300000   1.000     
1.000   FT

12002860 12   Plum, prune, fresh                 0.300000   1.000     
1.000   FT

12002861 12   Plum, prune, fresh-babyfood        0.300000   1.000     
1.000   FT

12002870 12   Plum, prune, dried                 0.300000   2.600     
1.000   FT E.P

  Full comment: FT E.PF

12002871 12   Plum, prune, dried-babyfood        0.300000   2.600     
1.000   FT E.P

  Full comment: FT E.PF

12002880 12   Plum, prune, juice                 0.300000   1.400     
1.000   FT

12002881 12   Plum, prune, juice-babyfood        0.300000   1.400     
1.000   FT

60003010 P    Poultry, other, meat               0.050000   1.000     
1.000   

60003020 P    Poultry, other, liver              0.050000   1.000     
1.000   

60003030 P    Poultry, other, meat byproducts    0.050000   1.000     
1.000   

60003040 P    Poultry, other, fat                0.050000   1.000     
1.000   

60003050 P    Poultry, other, skin               0.050000   1.000     
1.000   

10003070 10   Pummelo                            2.000000   1.000     
1.000   

09023080 9B   Pumpkin                            0.500000   1.000     
1.000   

09023090 9B   Pumpkin, seed                      0.500000   1.000     
1.000   

11003100 11   Quince                             5.000000   1.000     
1.000   TOL

29003120 M    Rabbit, meat                       0.010000   1.000     
1.000   

13013200 13A  Raspberry                         12.000000   1.000     
1.000   

13013201 13A  Raspberry-babyfood                12.000000   1.000     
1.000   

13013210 13A  Raspberry, juice                  12.000000   1.000     
1.000   

13013211 13A  Raspberry, juice-babyfood         12.000000   1.000     
1.000   

95003330 O    Sapote, Mamey                      1.000000   1.000     
1.000   

26003390 M    Sheep, meat                        0.010000   1.000     
1.000   

26003391 M    Sheep, meat-babyfood               0.010000   1.000     
1.000   

26003400 M    Sheep, meat byproducts             0.010000   1.000     
1.000   

26003410 M    Sheep, fat                         0.050000   1.000     
1.000   

26003411 M    Sheep, fat-babyfood                0.050000   1.000     
1.000   

26003420 M    Sheep, kidney                      0.010000   1.000     
1.000   

26003430 M    Sheep, liver                       0.010000   1.000     
1.000   

09023560 9B   Squash, summer                     0.500000   1.000     
1.000   

09023561 9B   Squash, summer-babyfood            0.500000   1.000     
1.000   

09023570 9B   Squash, winter                     0.500000   1.000     
1.000   

09023571 9B   Squash, winter-babyfood            0.500000   1.000     
1.000   

95003590 O    Strawberry                         2.000000   1.000     
1.000   

95003591 O    Strawberry-babyfood                2.000000   1.000     
1.000   

95003600 O    Strawberry, juice                  2.000000   1.000     
1.000   

95003601 O    Strawberry, juice-babyfood         2.000000   1.000     
1.000   

10003690 10   Tangerine                          2.000000   1.000     
1.000   

10003700 10   Tangerine, juice                   2.000000   0.060     
1.000   

08003740 8    Tomatillo                          1.000000   1.000     
1.000   

08003750 8    Tomato                             1.000000   0.830     
1.000   

08003751 8    Tomato-babyfood                    1.000000   0.830     
1.000   

08003760 8    Tomato, paste                      1.000000   0.300     
1.000   

08003761 8    Tomato, paste-babyfood             1.000000   0.300     
1.000   

08003770 8    Tomato, puree                      1.000000   0.830     
1.000   

08003771 8    Tomato, puree-babyfood             1.000000   0.830     
1.000   

08003780 8    Tomato, dried                      1.000000  11.870     
1.000   

08003781 8    Tomato, dried-babyfood             1.000000  11.870     
1.000   

08003790 8    Tomato, juice                      1.000000   0.050     
1.000   

50003820 P    Turkey, meat                       0.050000   1.000     
1.000   

50003821 P    Turkey, meat-babyfood              0.050000   1.000     
1.000   

50003830 P    Turkey, liver                      0.050000   1.000     
1.000   

50003831 P    Turkey, liver-babyfood             0.050000   1.000     
1.000   

50003840 P    Turkey, meat byproducts            0.050000   1.000     
1.000   

50003841 P    Turkey, meat byproducts-babyfood   0.050000   1.000     
1.000   

50003850 P    Turkey, fat                        0.050000   1.000     
1.000   

50003851 P    Turkey, fat-babyfood               0.050000   1.000     
1.000   

50003860 P    Turkey, skin                       0.050000   1.000     
1.000   

50003861 P    Turkey, skin-babyfood              0.050000   1.000     
1.000   

14003910 14   Walnut                             0.100000   1.000     
1.000   

86010000 O    Water, direct, all sources         0.001800   1.000     
1.000   

86020000 O    Water, indirect, all sources       0.001800   1.000     
1.000   

09013990 9A   Watermelon                         0.500000   1.000     
1.000   

09014000 9A   Watermelon, juice                  0.500000   1.000     
1.000   

Attachment 4: Results of Chronic Dietary Exposure Analysis

U.S. Environmental Protection Agency                                
Ver. 2.00

DEEM-FCID Chronic analysis for FENPROPATHRIN                    (1994-98
data)

Residue file name: C:\Documents and
Settings\aparmar\Desktop\Fenpropathrin DA\v3.1 (Final)\v3.1 Chronic
R98.R98

                                                 Adjustment factor #2
NOT used.

Analysis Date 10-14-2008/09:49:27     Residue file dated:
10-14-2008/09:31:58/8

Reference dose (RfD, Chronic) = .025 mg/kg bw/day

COMMENT 1: CPAD 0.025 mg/kg - no PCT, Tolerance and FT Data

========================================================================
=======

                    Total exposure by population subgroup

------------------------------------------------------------------------
-------

                                                    Total Exposure

                                        
-----------------------------------

          Population                         mg/kg             Percent
of   

           Subgroup                       body wt/day             Rfd   
   

--------------------------------------   -------------      
---------------

U.S. Population (total)                     0.003622               
14.5%

U.S. Population (spring season)             0.003696               
14.8%

U.S. Population (summer season)             0.003743               
15.0%

U.S. Population (autumn season)             0.003386               
13.5%

U.S. Population (winter season)             0.003680               
14.7%

Northeast region                            0.003786               
15.1%

Midwest region                              0.003544               
14.2%

Southern region                             0.003176               
12.7%

Western region                              0.004267               
17.1%

Hispanics                                   0.003993               
16.0%

Non-hispanic whites                         0.003559               
14.2%

Non-hispanic blacks                         0.003275               
13.1%

Non-hisp/non-white/non-black                0.004766               
19.1%

All infants (< 1 year)                      0.005819               
23.3%

Nursing infants                             0.003675               
14.7%

Non-nursing infants                         0.006633               
26.5%

Children 1-6  yrs                           0.008874               
35.5%

Children 7-12 yrs                           0.004855               
19.4%

Females 13-19 (not preg or nursing)         0.002416                
9.7%

Females 20+ (not preg or nursing)           0.002974               
11.9%

Females 13-50 yrs                           0.002925               
11.7%

Females 13+ (preg/not nursing)              0.003179               
12.7%

Females 13+ (nursing)                       0.004041               
16.2%

Males 13-19 yrs                             0.002711               
10.8%

Males 20+ yrs                               0.002737               
10.9%

Seniors 55+                                 0.003294               
13.2%

Children 1-2 yrs                            0.010325               
41.3%

Children 3-5 yrs                            0.008644               
34.6%

Children 6-12 yrs                           0.005130               
20.5%

Youth 13-19 yrs                             0.002572               
10.3%

Adults 20-49 yrs                            0.002644               
10.6%

Adults 50+ yrs                              0.003265               
13.1%

Females 13-49 yrs                           0.002678               
10.7%

------------------------------------------------------------------------
-------

Attachment 5: RDF Files

Fenpropathrin Acute Residue Distribution Files and Chronic Point
Estimates

RDF #1

Apple FT Data

100%CT

8 samples/8 detects

TOTALNZ=8

TOTALZ=0

0.36

1.4

0.95

1.3

0.51

0.65

0.40

0.56

	RDF #4

Cherry FT Data

100%CT

12 samples/12 detects

TOTALNZ=24

TOTALZ=0

1.83

1.97

2.02

1.60

1.44

1.43

3.18

3.33

1.59

1.43

3.53

3.23

	RDF #3

Grape FT Data

100%CT

24 samples/24 detects

TOTALNZ=24

TOTALZ=0

0.31

0.43

0.60

0.90

0.42

0.62

0.45

0.44

1.6

1.3

1.0

0.48

	3.3

2.9

0.81

1.4

1.4

0.72

1.5

1.5

0.93

1.1

1.3

1.5

Mean field trial value for chronic analysis: 0.77	Mean field trial value
for chronic analysis: 2.22	Mean field trial value for chronic analysis:
1.12

RDF #5

Peach FT Data

100%CT

20
samples/20搠瑥捥獴名呏䱁婎㈽ര佔䅔婌〽܍䑒⁆㈣倍慥⁲
呆䐠呁ു〱┰呃㠍猠浡汰獥㠯搠瑥捥獴名呏䱁婎㠽名呏
䱁㵚ര」㈮ഷ⸰㜲ㄍ㈮ഉ⸱റ⸰ㄳ」㈮हㄍ㘮㈍〮഍഍
切䙄⌠ശ汐浵⁳呆䐠瑡ൡ〱┰呃ㄍ‱慳灭敬⽳ㄱ搠瑥捥
獴名呏䱁婎ㄽറ佔䅔婌〽഍⸰ㄵ」㔮സ⸰㌲」㈮ള⸰㤲
」㈮റ⸰㜳」㈮ഷ⸰㐲

A

I

J

h

i

x

z

Ú

á

ä

ì

î

õ

h

@

A

i

‚

´

Ô

Õ

Ù

Ú

 

 

 

!

h

@

&

@

&

&

@

&

&

&

 h¿y

&

&

&

&

&

&

&

&

&

&

&

&

 h¿y

&

@

&

@

&

@

&

@

&

@

&

@

&

@

@

&

@

&

@

&

@

&

@

&

@

&

@

&

@

&

@

&

@

&

@

&

@

&

@

J

†

Í

Î

Ñ

@

Š

Ô

Õ

	

摧毗fᤀ	

5

@

I

J

O

T

Y

^

c

h

m

r

w

|

†

‡

Ž

摧毗f᐀Ž

œ

£

¹

Ä

Í

Î

ˆ

ˆ

ê

ï

ô

ù

ý

ˆ

ˆ

ˆ

摧毗fఀ0.20

0.18

0.66

0.66

0.76

0.63

0.56

0.73

0.91

1.11

1.05

1.01	0.69

0.72

0.79

0.67

0.61

0.54

0.39

0.49

1.00

0.84

Used for: Apricot, Nectarine

Mean field trial value for chronic analysis: 0.74	Mean field trial value
for chronic analysis: 0.88	Mean field trial value for chronic analysis:
0.30

Fenpropathrin	Dietary Exposure and Risk Assessment	DP Number:	 D356137

PC Code:  127901

________________________________________________________________________
___________________

 PAGE   

Page   PAGE  1  of   NUMPAGES  21 

DRAFT – Confidential, Internal, and Deliberative Material

[Chemical Name]	Dietary Exposure and Risk Assessment	DP Number:
[xxxxxxx]

PC Code:  [xxxxxx]