Document ID: EPA-HQ-OPP-2012-0107-0008
Agency: epa
Document Type: Supporting & Related Material
Title: 
Posted Date: 2013-05-15T04:00Z

UNITED STATES ENVIRONMENTAL PROTECTION AGENCY
                                       
                            WASHINGTON, D.C.  20460
                                       
                                                           OFFICE OF           
                                                            CHEMICAL SAFETY AND
                                                           POLLUTION PREVENTION

MEMORANDUM

DATE:  	26-MAR-2013

SUBJECT:	Spirotetramat:  Acute and Chronic Dietary (Food and Drinking Water) Exposure and Risk Assessment to Support the Section 3 Registration Request For Use of Spirotetramat on Taro, Leaves; Watercress; Pomegranate; Banana; Vegetable, Bulb, Group 3-07; Low growing Berry Subgroup 13-07H, Except Strawberry and Lowbush Blueberry; Bushberry Subgroup 13-07B; Artichoke, Globe; Vegetable, Fruiting, Group 8-10; Fruit, Pome, Group 11-10; Fruit, Citrus, Group 10-10; Pineapple; and Coffee; and Tolerances without U.S. Registration in/on Corn, Sweet, Kernel Plus Cob with Husks Removed as Part of the U.S.-Canada Regulatory Cooperation Council (RCC) Pilot Project. 

PC Code:  392201
DP No.:  D398858
Decision No.:  459092
Registration No.:  264-1050
Petition No.:  1E7958
Regulatory Action:  Section 3
Risk Assessment Type:  Dietary
Case No.:  7452
TXR No.:  NA
CAS No.:  203313-25-1
MRID No.:  NA
40 CFR:  §180.641

FROM:	Julie L. Van Alstine, MPH, Environmental Health Scientist
		Risk Assessment Branch 1 (RAB1)/Health Effects Division (HED; 7509P)

THROUGH:	Douglas A. Dotson, Ph.D., Chemist
      Kristin Rury, Biologist 
      Dietary Exposure Science Advisory Council (DESAC)
            HED (7509P)
            and
            George F. Kramer, Ph.D., Branch Senior Chemist
            RAB1/HED (7509P)
            
TO:		Barbara Madden/Laura Nollen, RM 05
      Registration Division (RD; 7505P)

Executive Summary
Acute and chronic dietary-exposure and risk assessments were conducted using the Dietary Exposure Evaluation Model software with the Food Commodity Intake Database (DEEM-FCID) Version 3.16, which uses food consumption data from the U.S. Department of Agriculture's National Health and Nutrition Examination Survey, What We Eat in America, (NHANES/WWEIA) from 2003 through 2008.  The analyses were performed to support a proposed Section 3 registration request by Interregional Research Project Number 4 (IR-4) for the application of the active ingredient spirotetramat (cis-3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl ethyl carbonate) to taro, watercress, pomegranates, bananas, bulb vegetables, low-growing berries (except strawberries), bushberries, globe artichokes, fruiting vegetables, pome fruit, citrus fruit, pineapples, and coffee and, as part of the U.S.-Canada Regulatory Cooperation Council (RCC) pilot project, the establishment of a tolerance without U.S. registration for residues of spirotetramat in/on corn, sweet, kernel plus cob with husks removed.  These analyses have been reviewed by two peer reviewers of the DESAC, per the DESAC Standard Operating Procedure (SOP) 2012.1.  

Acute Dietary (Food and Drinking Water) Exposure Results and Characterization 
The acute analysis assumed 100% crop treated (CT), tolerance-level residues for all foods, and DEEM 7.81 default processing factors (where provided).  Dietary risk estimates were determined considering exposures from food plus drinking water using estimated drinking water concentrations (EDWCs) for surface water sources provided by the Environmental Fate and Effects Division (EFED).  EDWC values were generated using the watercress use pattern and the Tier 1 Rice Model v.1.0 since the proposed Section 3 use on watercress yielded the highest acute EDWC values.  The acute dietary risk assessment shows that for all included commodities, the acute dietary risk estimates at the 95[th] percentile are not of concern to HED [i.e., <100% acute population-adjusted dose (aPAD)].  The resulting acute dietary (food + water) risk estimates utilized 7% of the aPAD for the general U.S. population and 16% of the aPAD for children 1-2 years old, the most highly exposed population subgroup.   

Chronic Dietary (Food and Drinking Water) Exposure Results and Characterization
The chronic dietary assessment assumed 100% CT, average field trial residues for some commodities, and tolerance-level residues for the remaining commodities.  Some empirical processing factors were used along with DEEM 7.81 default processing factors (where provided).  EDWC values were generated using the watercress use pattern and the Tier 1 Rice Model v.1.0 since the proposed Section 3 use on watercress yielded the highest chronic EDWC values.  The chronic dietary risk assessment shows that for all included commodities, the chronic dietary risk estimates are not of concern to HED [i.e., <100% chronic population-adjusted dose (cPAD)].  The resulting chronic dietary (food + water) risk estimates utilized 36% of the cPAD for the general U.S. population and 76% of the cPAD for children 1-2 years old, the most highly exposed population subgroup.   

Cancer 
Spirotetramat was classified as "not likely to be carcinogenic to humans"; therefore, a cancer dietary assessment was not performed. 

I.	Introduction
Dietary risk assessment incorporates both exposure and toxicity of a given pesticide.  For acute and chronic assessments, the risk is expressed as a percentage of a maximum acceptable dose (i.e., the dose that HED has concluded will result in no unreasonable adverse health effects).  This dose is referred to as the population-adjusted dose (PAD).  The PAD is equivalent to the point of departure (POD, NOAEL, LOAEL, e.g.) divided by the required uncertainty or safety factors.

For acute and non-cancer chronic exposures, HED is concerned when estimated dietary risk exceeds 100% of the PAD.  References that discuss the acute and chronic risk assessments in more detail are available on the EPA/pesticides web site:  "Available Information on Assessing Exposure from Pesticides, A User's Guide," 21-JUN-2000, web link:  http://www.epa.gov/fedrgstr/EPA-PEST/2000/July/Day-12/6061.pdf; or see SOP 99.6 (20-AUG-1999).

The most recent dietary risk assessment for spirotetramat was conducted on 01-AUG-2012 (Memo, J. Van Alstine; D404051).

II.	Residue Information
Residues of Concern:  The nature of the residue in plants, rotational crops, and livestock is adequately understood based on acceptable metabolism studies conducted on apple, lettuce, cotton, potato, rotational crops, lactating goats, and laying hens.  The residues of concern for the tolerance expression and risk assessment for plant commodities are spirotetramat and its metabolites BYI 08330-enol, BYI 08330-ketohydroxy, BYI08330-enol-Glc, and BYI 08330-mono-hydroxy.  Based on the currently proposed uses, the residues of concern for the tolerance expression for livestock commodities are spirotetramat and its metabolite BYI 08330-enol, and the residues of concern for the risk assessment for livestock commodities are spirotetramat and its metabolites BYI 08330-enol and BYI 08330-enol-GA (Memo, J. Tyler et al., 4/16/08; D333437).  

Established Tolerances:  Permanent tolerances for the combined residues of spirotetramat and its metabolites BYI 08330-enol, BYI 08330-ketohydroxy, BYI08330-enol-Glc, and BYI 08330-mono-hydroxy, calculated as spirotetramat equivalents, are currently established in/on a wide variety of crops (40 CFR §180.641).  

Recommended Tolerances:  Based on the residue chemistry data submitted with the current petition, HED recommended for establishment of the tolerances outlined in Table 1 for the combined residues of spirotetramat and its metabolites BYI 08330-enol, BYI 08330-ketohydroxy, BYI08330-enol-Glc, and BYI 08330-mono-hydroxy, calculated as the stoichiometric equivalent of spirotetramat.

Table 1.  Tolerance Summary for Spirotetramat.
Commodity
                          Recommended Tolerance (ppm)
Taro, leaves
                                      9.0
Watercress
                                      2.0
Pomegranate
                                     0.50
Banana[1]
                                      4.0
Vegetable, bulb, group 3-07 
                                     0.80
Low growing berry subgroup 13-07H, except strawberry and lowbush blueberry
                                     0.30
Bushberry subgroup 13-07B 
                                      3.0
Artichoke, globe
                                      1.5
Vegetable, fruiting, group 8-10
                                      2.5
Fruit, pome, group 11-10
                                     0.70
Fruit, citrus, group 10-10
                                     0.60
Pineapple
                                     0.30
Coffee, green bean
                                     0.20
Coffee, instant
                                     0.50
Corn, sweet, kernel plus cob with husks removed[2]
                                      1.5
[1]  This tolerance should be established under 40 CFR §180.641(c) Tolerances with regional registrations.
[2]  There are no U.S. registrations as of [date] for use on corn, sweet.
   
Residue Data Used for Acute and Chronic Assessments:  The acute assessment assumed tolerance-level residues.  The chronic assessment incorporated average field trial residues for some commodities (see Attachment 3) and tolerance-level residues for the remaining commodities.  Additionally, the potato average field trial residue was translated to sweet potatoes using HED SOP 2000.1.  The residue levels for livestock commodities were not adjusted for the additional metabolite of concern for the risk assessment (BYI 08330-enol-GA) as the tolerance-level values are sufficient to cover the total residues of spirotetramat, BYI 08330-enol, and BYI 08330-enol-GA (G. Kramer, 09-APR-2010; D362952).  The tolerances in 40 CFR §180.641 for residues in/on feijoa, papaya, and Spanish lime do not match the recommended tolerances from the previous assessment (Memo, J. Van Alstine et al., 22-DEC-2010; D368785).  For feijoa and Spanish lime, the HED-recommended tolerances were higher than the tolerance in the 40 CFR; therefore, the recommended tolerances of 2.5 ppm and 13 ppm, respectively, were used in this assessment.  For papaya, the HED-recommended tolerance of 0.35 ppm is lower than the tolerance in the 40 CFR; therefore, the higher tolerance of 2.5 ppm from the 40 CFR was used in this assessment as a conservative assumption.  Additionally, HED recommended a tolerance of 2.5 ppm for residues in/on persimmon, which was excluded from the 40 CFR.  This tolerance has been included in the assessment.  Finally, the recommended tolerance of 0.80 ppm for the bulb vegetable subgroup 3-07 was used for the entire crop group because this tolerance will replace the currently established tolerance of 0.30 ppm for bulb onion subgroup 3A-07.  

The USDA Pesticide Data Program (PDP) monitored pesticide residues in catfish in 2008, 2009, and 2010; however, the samples were not analyzed for spirotetramat.  As a result, residues in fish were not included in the assessment.

Processing Factors:  For the acute assessment, DEEM 7.81 default processing factors were used (where provided).  For the chronic assessment, empirical processing factors were used for the following processed commodities:  apple, orange, grape, tomato, and pineapple juice; applesauce; and dried apple and tomato.  The processing factors have been set to 1 for dried plums and tomato paste and puree because separate tolerances were not required for these commodities based on the available processing data and since tolerance-level residues were used in the assessment.  DEEM 7.81 default processing factors were used for the remaining processed commodities (where provided).  (See Attachment 3.)

III.	Percent Crop Treated
Both the acute and chronic assessments assumed 100% CT for all commodities.  

IV.	Drinking Water Data
The drinking water residues used in the dietary risk assessment were provided by EFED (Memo, J. Meléndez, 19-JUL-2012; D398507).  The drinking water models and their descriptions are available at the EPA internet site: http://www.epa.gov/oppefed1/models/water/. 

Exposure to spirotetramat in surface water is possible through surface water runoff, soil erosion, and/or off-target spray drift.  The mobility of spirotetramat is relatively high [Kd range 3.58-5.52 mL/g, KOC range 184-437 mL/gOC (moderately mobile)] and it is labile under many conditions, especially under aerobic soil metabolism conditions.  Nonetheless, its total residues are relatively persistent.  The Tier I EDWCs for spirotetramat and for its major transformation products, spirotetramat-enol and spirotetramat-ketohydroxy, were calculated using SCI-GROW v.2.3 (groundwater, applications to bananas and plantains) and the Tier 1 Rice Model v.1.0 (surface water, as a surrogate for applications to watercress).  The Tier 1 Rice Model v.1.0 resulted in the highest EDWC for use in the acute and chronic assessments.  Therefore, the surface water EDWC value of 0.395 ppm was incorporated in DEEM-FCID into the food categories "water, direct, all sources" and "water, indirect, all sources" for both the acute and chronic assessments.  

Watercress is typically grown in clean, flowing water, 2 to 3 inches deep.  Based on the previous review and information provided by the registrant and IR-4, it appears that watercress is grown in a bed of water that drains to a ditch and is constantly recirculated.  The circulation of water is stopped 24 hours before chemical application and is turned back on 24 hours after application.  The Agency does not currently have a methodology for exposure assessment for crops cultivated in flowing water, such as watercress.  The EFED Tier 1 Rice model v.1.0 has, therefore, been used as the basis of the assessment, and the results have been characterized to reflect differences between the capabilities of this model and the watercress cultivation practices.  

EFED is concerned primarily about the total toxic residues (TTR), as opposed to individual metabolites (spirotetramat, spirotetramat-enol, and spirotetramat-ketohydroxy), from discharge towards adjacent bodies of water at the end of the season.  Individual metabolites were not modeled because this would double count the mass of pesticide and the transformation products in this particular model.  Rice cultivation differs from watercress cultivation in that for the latter, the water is constantly flowing, while for rice, the field is flooded.  The Tier 1 Rice Model v.1.0 provides a conservative, screening-level estimate.  Crop interception, pesticide degradation, stream flow, and runoff dilution from the areas in the watershed which are not treated all have the potential to reduce the conservative EDWCs generated by the Tier 1 Rice Model.  

Table 2.  Maximum Tier I EDWCs for Drinking Water Risk Assessment Based on Ground or Aerial Application of Spirotetramat on Plantains and Bananas (for Groundwater) at 1.25 lb a.i./A/Season, and Ground, Aerial, or Chemigation Applications on Watercress (for Surface Water) at 0.4 lb a.i./A/Season.
Drinking Water Source (MODEL)

                                     EDWC

Chemical:
                                    Parent
                                 Spirotetramat
                              Spirotetramat-enol
                           Spirotetramat-ketohydroxy
                         Total Toxic Residues (TTR)[1]

Risk \ Units
                                     (ppb)
                                     (ppb)
                                     (ppb)
                                     (ppb)
Ground-water (SCI-GROW)
Acute & Chronic[2]
                                 7.06 x 10[-5]
                                 5.15 x 10[-5]
                                 1.12 x 10[-3]
                                 1.24 x 10[-3]
Surface Water (Tier 1 Rice Model v.1.0)
Acute & Chronic[2]
                                      N/A
                                      N/A
                                      N/A
                                      395
 TTR = Total Toxic Residues (sum of spirotetramat + spirotetramat-enol + spirotetramat-ketohydroxy).
[2] Surface-water concentrations calculated by the Tier I Rice Model v1.0 and ground water concentrations calculated by SCI-GROW do not distinguish between peak and chronic concentrations.

V.	DEEM-FCID Program and Consumption Information
Spirotetramat acute and chronic dietary exposure assessments were conducted using DEEM-FCID, Version 3.16, which incorporates consumption data from USDA's NHANES/WWEIA from 2003 through 2008.  The data are based on the reported consumption of more than 20,000 individuals over two non-consecutive survey days.  Foods "as consumed" (e.g., apple pie) are linked to EPA-defined food commodities (e.g., apples, peeled fruit - cooked; fresh or N/S; baked; or wheat flour - cooked; fresh or N/S, baked) using publicly available recipe translation files developed jointly by USDA/ARS and EPA.  For chronic exposure assessment, consumption data are averaged for the entire U.S. population and within population subgroups.  However, for acute exposure assessment, consumption data are retained as individual consumption events.  Based on analysis of the 2003-2008 WWEIA consumption data, which took into account dietary patterns and survey respondents, HED concluded that it is most appropriate to report risk for the following population subgroups: the general U.S. population, all infants (<1 year old), children 1-2, children 3-5, children 6-12, youth 13-19, adults 20-49, females 13-49, and adults 50-99 years old.

For a chronic dietary exposure assessment, an estimate of the residue level in each food or food-form (e.g., orange or orange juice) on the food commodity residue list is multiplied by the average daily consumption estimate for that food/food form to produce a residue intake estimate.  The resulting residue intake estimate for each food/food form is summed with the residue intake estimates for all other food/food forms on the commodity residue list to arrive at the total average estimated exposure.  Exposure is expressed in mg/kg body weight/day and as a percent of the cPAD.  This procedure is performed for each population subgroup.

For an acute exposure assessment, individual one-day food consumption data are used on an individual-by-individual basis.  The reported consumption amounts of each food item can be multiplied by a residue point estimate and summed to obtain a total daily pesticide exposure for a deterministic exposure assessment, or "matched" in multiple random pairings with residue values and then summed in a probabilistic assessment.  The resulting distribution of exposures is expressed as a percentage of the aPAD on both a user (i.e., only those who reported eating relevant commodities/food forms) and a per-capita (i.e., those who reported eating the relevant commodities as well as those who did not) basis.  In accordance with HED policy, per capita exposure and risk are reported for analyses performed at all levels of refinement.  However, for deterministic assessments, any significant differences in user vs. per capita exposure and risk are specifically identified and noted in the risk assessment.

VI.	Toxicological Information
Table 3 summarizes the toxicological doses and endpoints for spirotetramat concerning dietary exposure assessment.  The endpoints have been reviewed by the risk assessment team and are considered appropriate for the current risk assessment.  

Table 3.  Summary of Toxicological Doses and Endpoints for Spirotetramat for Use in Dietary Human-Health Risk Assessments. 
                               Exposure Scenario
                              Point of Departure
                        Uncertainty/FQPA Safety Factors
                       RfD, PAD, LOC for Risk Assessment
                   Study and Relevant Toxicological Effects
Acute Dietary (General Population, including Infants and Children)
NOAEL = 100
mg/kg/day
UFA = 10X
UFH = 10X
UFFQPA = 1X 
aRfD = aPAD = 1.0 mg/kg/day
Acute neurotoxicity (rat; oral gavage)
LOAEL = 200 mg/kg based on clinical signs (M&F) and decreased motor activity (M).
Chronic Dietary (All Populations)
NOAEL = 5
mg/kg/day
UFA = 10X
UFH = 10X
UFFQPA = 1X
cRfD = cPAD = 0.05 mg/kg/day[1]
Chronic toxicity (dog; dietary)
LOAEL = 20 mg/kg/day (M) based on thymus involution.
Cancer (Oral, Dermal, Inhalation)
Classification:  "not likely to be carcinogenic to humans" based on lack of evidence of carcinogenicity in two oral rodent carcinogenicity studies.
Abbreviations:  UF = uncertainty factor, UFA = extrapolation from animal to human (interspecies), UFH = potential variation in sensitivity among members of the human population (intraspecies), UFFQPA = FQPA Safety Factor, NOAEL = no-observed adverse-effect level, LOAEL = lowest-observed adverse-effect level, RfD = reference dose (a = acute, c = chronic), PAD = population-adjusted dose, LOC = level of concern.
[1] The cRfD has been harmonized across American (USEPA), Canadian (PMRA), and Austrian (AGES) regulatory agencies.  However, it is noted that USEPA considered a NOAEL = 6 mg/kg/day in males and a NOAEL = 19 mg/kg/day in females to more accurately reflect the toxicological data.  The difference between 5 mg/kg/day (NOAEL in females for PMRA and AGES) and 6 mg/kg/day was considered negligible for risk assessment.

VII.	Results/Discussion 
For acute and chronic assessments, HED is concerned when dietary risk exceeds 100% of the PAD.  The DEEM-FCID analyses estimate the dietary exposure of the U.S. population and various population subgroups.  The results reported in Table 4 are for the general U.S. population, all infants (<1 year old), children 1-2, children 3-5, children 6-12, youth 13-19, females 13-49, adults 20-49, and adults 50-99 years.  

Results of Acute and Chronic Dietary Exposure Analyses

The acute dietary exposure for food and drinking water utilized 7% of the aPAD for the U.S. population.  The acute dietary exposure estimate for the highest reported exposed population subgroup, children 1-2 years old, utilized 16% of the aPAD.  The chronic dietary exposure estimate for food and drinking water utilized 36% of the cPAD for the U.S. population.  The chronic dietary exposure for the highest reported exposed population subgroup, children 1-2 years old, utilized 76% of the cPAD.  Spirotetramat was classified as "not likely to be carcinogenic to humans"; therefore, a cancer dietary assessment was not performed.  The results of the acute and chronic dietary exposure analyses are reported in Table 4.  

 Table 4.  Summary of Dietary (Food and Drinking Water) Exposure Risk for Spirotetramat[1].
                              Population Subgroup
                       Acute Dietary (95[th] Percentile)
                                Chronic Dietary
                                        
                          Dietary Exposure (mg/kg/day)
                                     % aPAD
                                Dietary Exposure
                                  (mg/kg/day)
                                     % cPAD
 General U.S. Population
                                    0.066115
                                       7
                                    0.017785
                                      36
 All Infants (<1 year old)
                                    0.137642
                                      14
                                    0.036886
                                      74
 Children 1-2 years old
                                    0.155241
                                      16
                                    0.038038
                                      76
 Children 3-5 years old
                                    0.125606
                                      13
                                    0.030925
                                      62
 Children 6-12 years old
                                    0.075624
                                       8
                                    0.019418
                                      39
 Youth 13-19 years old
                                    0.046354
                                       5
                                    0.013149
                                      26
 Adults 20-49 years old
                                    0.053000
                                       5
                                    0.016159
                                      32
 Adults 50-99 years old
                                    0.050326
                                       5
                                    0.016494
                                      33
 Females 13-49 years old
                                    0.052999
                                       5
                                    0.015902
                                      32
 1 The values for the highest exposed population for each type of risk assessment are bolded.
 
Further refinement to the analyses could be made through the use of additional average field trial values and translation of average field trial residues to other commodities using HED SOP 2000.1, additional empirical processing factors, incorporation of percentages of crops treated with spirotetramat, or monitoring data.  Since risk estimates are below HED's level of concern, a more highly refined analysis is not required at this time.
 
 VIII.	Conclusions
Acute and chronic dietary exposure and risk assessments were conducted for the proposed food uses and permanent tolerances of spirotetramat, including potential exposure from drinking water.  The acute and chronic dietary (food + drinking water) exposure and risk estimates for spirotetramat are below HED's level of concern for the general U.S. population and all population subgroups.  The most highly exposed population subgroup for both the acute and chronic assessments was children 1-2 years old.  This population subgroup utilized 16% of the aPAD and 76% of the cPAD.

IX.	List of Attachments
 Attachment 1:  Acute Food plus Water Residue Input File
 Attachment 2:  Acute Results File
 Attachment 3:  Average Field Trial Residues and Processing Factors Used in the Chronic Assessment
 Attachment 4:  Chronic Food plus Water Residue Input File
 Attachment 5:  Chronic Results File
 
RDI:  DE SAC Reviewers:  11-26-2012; G. Kramer: 11-26-2012
DP No.:  D398858
Petition No.:  1E7958
PC Code:  392201
J. L.Van Alstine:S-10951:PY-S:(703)603-8866:7509P:RAB1
                                       
Attachment 1:  Acute and Chronic Food plus Water Residue Input File

Filename: C:\Documents and Settings\jlangsda\My Documents\Chemicals\Spirotetramat\2012 RCC\Dietary\Sent to Reviewers\updated to include Kiwi\updated SPIROTETRAMAT__ACUTE__21 Dec 2012.R08
Chemical: Spirotetramat
RfD(Chronic): .05 mg/kg bw/day  NOEL(Chronic): 0 mg/kg bw/day
RfD(Acute): 1 mg/kg bw/day  NOEL(Acute):  0 mg/kg bw/day
Date created/last modified: 12-21-2012/11:35:33       Program ver. 3.16, 03-08-d
Comment: + emp proc fact
-----------------------------------------------------------------------------------
   EPA     Crop                                   Def Res     Adj.Factors   Comment
   Code     Grp  Commodity Name                    (ppm)       #1    #2   
---------- ---- -------------------------------  ----------  ------ ------  -------
0103015000 1CD  Arrowroot, flour                   0.600000   1.000  1.000  
0103015001 1CD  Arrowroot, flour-babyfood          0.600000   1.000  1.000  
0103017000 1CD  Artichoke, Jerusalem               0.600000   1.000  1.000  
0103082000 1CD  Cassava                            0.600000   1.000  1.000  
0103082001 1CD  Cassava-babyfood                   0.600000   1.000  1.000  
0103139000 1CD  Dasheen, corm                      0.600000   1.000  1.000  
0103166000 1CD  Ginger                             0.600000   1.000  1.000  
0103166001 1CD  Ginger-babyfood                    0.600000   1.000  1.000  
0103167000 1CD  Ginger, dried                      0.600000   1.000  1.000  
0103296000 1C   Potato, chips                      0.600000   1.000  1.000  
0103297000 1C   Potato, dry (granules/ flakes)     1.600000   1.000  1.000  
0103297001 1C   Potato, dry (granules/ flakes)-b   1.600000   1.000  1.000  
0103298000 1C   Potato, flour                      1.600000   1.000  1.000  
0103298001 1C   Potato, flour-babyfood             1.600000   1.000  1.000  
0103299000 1C   Potato, tuber, w/peel              0.600000   1.000  1.000  
0103299001 1C   Potato, tuber, w/peel-babyfood     0.600000   1.000  1.000  
0103300000 1C   Potato, tuber, w/o peel            0.600000   1.000  1.000  
0103300001 1C   Potato, tuber, w/o peel-babyfood   0.600000   1.000  1.000  
0103366000 1CD  Sweet potato                       0.600000   1.000  1.000  
0103366001 1CD  Sweet potato-babyfood              0.600000   1.000  1.000  
0103371000 1CD  Tanier, corm                       0.600000   1.000  1.000  
0103387000 1CD  Turmeric                           0.600000   1.000  1.000  
0103406000 1CD  Yam, true                          0.600000   1.000  1.000  
0103407000 1CD  Yam bean                           0.600000   1.000  1.000  
0301165000 3A   Garlic, bulb                       0.800000   1.000  1.000  
0301165001 3A   Garlic, bulb-babyfood              0.800000   1.000  1.000  
0301237000 3A   Onion, bulb                        0.800000   1.000  1.000  
0301237001 3A   Onion, bulb-babyfood               0.800000   1.000  1.000  
0301238000 3A   Onion, bulb, dried                 0.800000   9.000  1.000  
0301238001 3A   Onion, bulb, dried-babyfood        0.800000   9.000  1.000  
0301338000 3A   Shallot, bulb                      0.800000   1.000  1.000  
0302103000 3B   Chive, fresh leaves                0.800000   1.000  1.000  
0302198000 3B   Leek                               0.800000   1.000  1.000  
0302239000 3B   Onion, green                       0.800000   1.000  1.000  
0302338500 3B   Shallot, fresh leaves              0.800000   1.000  1.000  
0401005000 4A   Amaranth, leafy                    9.000000   1.000  1.000  
0401018000 4A   Arugula                            9.000000   1.000  1.000  
0401104000 4A   Chrysanthemum, garland             9.000000   1.000  1.000  
0401133000 4A   Cress, garden                      9.000000   1.000  1.000  
0401134000 4A   Cress, upland                      9.000000   1.000  1.000  
0401138000 4A   Dandelion, leaves                  9.000000   1.000  1.000  
0401150000 4A   Endive                             9.000000   1.000  1.000  
0401204000 4A   Lettuce, head                      9.000000   1.000  1.000  
0401205000 4A   Lettuce, leaf                      9.000000   1.000  1.000  
0401248000 4A   Parsley, leaves                    9.000000   1.000  1.000  
0401313000 4A   Radicchio                          9.000000   1.000  1.000  
0401355000 4A   Spinach                            9.000000   1.000  1.000  
0401355001 4A   Spinach-babyfood                   9.000000   1.000  1.000  
0402076000 4B   Cardoon                            9.000000   1.000  1.000  
0402085000 4B   Celery                             9.000000   1.000  1.000  
0402085001 4B   Celery-babyfood                    9.000000   1.000  1.000  
0402086000 4B   Celery, juice                      9.000000   1.000  1.000  
0402087000 4B   Celtuce                            9.000000   1.000  1.000  
0402152000 4B   Fennel, Florence                   9.000000   1.000  1.000  
0402322000 4B   Rhubarb                            9.000000   1.000  1.000  
0402367000 4B   Swiss chard                        9.000000   1.000  1.000  
0501061000 5A   Broccoli                           2.500000   1.000  1.000  
0501061001 5A   Broccoli-babyfood                  2.500000   1.000  1.000  
0501062000 5A   Broccoli, Chinese                  2.500000   1.000  1.000  
0501064000 5A   Brussels sprouts                   2.500000   1.000  1.000  
0501069000 5A   Cabbage                            2.500000   1.000  1.000  
0501071000 5A   Cabbage, Chinese, napa             2.500000   1.000  1.000  
0501072000 5A   Cabbage, Chinese, mustard          2.500000   1.000  1.000  
0501083000 5A   Cauliflower                        2.500000   1.000  1.000  
0501196000 5A   Kohlrabi                           2.500000   1.000  1.000  
0502063000 5B   Broccoli raab                      8.000000   1.000  1.000  
0502070000 5B   Cabbage, Chinese, bok choy         8.000000   1.000  1.000  
0502117000 5B   Collards                           8.000000   1.000  1.000  
0502194000 5B   Kale                               8.000000   1.000  1.000  
0502229000 5B   Mustard greens                     8.000000   1.000  1.000  
0502318000 5B   Rape greens                        8.000000   1.000  1.000  
0502389000 5B   Turnip, greens                     8.000000   1.000  1.000  
0600347000 6    Soybean, seed                      5.000000   1.000  1.000  
0600349000 6    Soybean, soy milk                  5.000000   1.000  1.000  
0600349001 6    Soybean, soy milk-babyfood or in   5.000000   1.000  1.000  
0600350000 6    Soybean, oil                       5.000000   1.000  1.000  
0600350001 6    Soybean, oil-babyfood              5.000000   1.000  1.000  
0601043000 6A   Bean, snap, succulent              2.500000   1.000  1.000  
0601043001 6A   Bean, snap, succulent-babyfood     2.500000   1.000  1.000  
0601257000 6A   Pea, edible podded, succulent      2.500000   1.000  1.000  
0601349500 6AB  Soybean, vegetable                 5.000000   1.000  1.000  
0602031000 6B   Bean, broad, succulent             2.500000   1.000  1.000  
0602033000 6B   Bean, cowpea, succulent            2.500000   1.000  1.000  
0602037000 6B   Bean, lima, succulent              2.500000   1.000  1.000  
0602255000 6B   Pea, succulent                     2.500000   1.000  1.000  
0602255001 6B   Pea, succulent-babyfood            2.500000   1.000  1.000  
0602259000 6B   Pea, pigeon, succulent             2.500000   1.000  1.000  
0603030000 6C   Bean, black, seed                  2.500000   1.000  1.000  
0603032000 6C   Bean, broad, seed                  2.500000   1.000  1.000  
0603034000 6C   Bean, cowpea, seed                 2.500000   1.000  1.000  
0603035000 6C   Bean,  great northern, seed        2.500000   1.000  1.000  
0603036000 6C   Bean, kidney, seed                 2.500000   1.000  1.000  
0603038000 6C   Bean, lima, seed                   2.500000   1.000  1.000  
0603039000 6C   Bean, mung, seed                   2.500000   1.000  1.000  
0603040000 6C   Bean, navy, seed                   2.500000   1.000  1.000  
0603041000 6C   Bean, pink, seed                   2.500000   1.000  1.000  
0603042000 6C   Bean, pinto, seed                  2.500000   1.000  1.000  
0603098000 6C   Chickpea, seed                     2.500000   1.000  1.000  
0603098001 6C   Chickpea, seed-babyfood            2.500000   1.000  1.000  
0603099000 6C   Chickpea, flour                    2.500000   1.000  1.000  
0603182000 6C   Guar, seed                         2.500000   1.000  1.000  
0603182001 6C   Guar, seed-babyfood                2.500000   1.000  1.000  
0603203000 6C   Lentil, seed                       2.500000   1.000  1.000  
0603256000 6C   Pea, dry                           2.500000   1.000  1.000  
0603256001 6C   Pea, dry-babyfood                  2.500000   1.000  1.000  
0603258000 6C   Pea, pigeon, seed                  2.500000   1.000  1.000  
0603348000 6C   Soybean, flour                     5.000000   1.000  1.000  
0603348001 6C   Soybean, flour-babyfood            5.000000   1.000  1.000  
0801374000 8A   Tomatillo                          2.500000   1.000  1.000  
0801375000 8A   Tomato                             2.500000   1.000  1.000  
0801375001 8A   Tomato-babyfood                    2.500000   1.000  1.000  
0801376000 8A   Tomato, paste                      2.500000   5.400  1.000  
0801376001 8A   Tomato, paste-babyfood             2.500000   5.400  1.000  
0801377000 8A   Tomato, puree                      2.500000   3.300  1.000  
0801377001 8A   Tomato, puree-babyfood             2.500000   3.300  1.000  
0801378000 8A   Tomato, dried                      2.500000  14.300  1.000  
0801378001 8A   Tomato, dried-babyfood             2.500000  14.300  1.000  
0801379000 8A   Tomato, juice                      2.500000   1.500  1.000  
0801380000 8A   Tomato, Tree                       2.500000   1.000  1.000  
0802148000 8BC  Eggplant                           2.500000   1.000  1.000  
0802234000 8BC  Okra                               2.500000   1.000  1.000  
0802270000 8B   Pepper, bell                       2.500000   1.000  1.000  
0802270001 8B   Pepper, bell-babyfood              2.500000   1.000  1.000  
0802271000 8B   Pepper, bell, dried                2.500000   1.000  1.000  
0802271001 8B   Pepper, bell, dried-babyfood       2.500000   1.000  1.000  
0802272000 8BC  Pepper, nonbell                    2.500000   1.000  1.000  
0802272001 8BC  Pepper, nonbell-babyfood           2.500000   1.000  1.000  
0802273000 8BC  Pepper, nonbell, dried             2.500000   1.000  1.000  
0901075000 9A   Cantaloupe                         0.300000   1.000  1.000  
0901187000 9A   Honeydew melon                     0.300000   1.000  1.000  
0901399000 9A   Watermelon                         0.300000   1.000  1.000  
0901400000 9A   Watermelon, juice                  0.300000   1.000  1.000  
0902021000 9B   Balsam pear                        0.300000   1.000  1.000  
0902088000 9B   Chayote, fruit                     0.300000   1.000  1.000  
0902102000 9B   Chinese waxgourd                   0.300000   1.000  1.000  
0902135000 9B   Cucumber                           0.300000   1.000  1.000  
0902308000 9B   Pumpkin                            0.300000   1.000  1.000  
0902309000 9B   Pumpkin, seed                      0.300000   1.000  1.000  
0902356000 9B   Squash, summer                     0.300000   1.000  1.000  
0902356001 9B   Squash, summer-babyfood            0.300000   1.000  1.000  
0902357000 9B   Squash, winter                     0.300000   1.000  1.000  
0902357001 9B   Squash, winter-babyfood            0.300000   1.000  1.000  
1001106000 10A  Citron                             0.600000   1.000  1.000  
1001107000 10A  Citrus hybrids                     0.600000   1.000  1.000  
1001108000 10A  Citrus, oil                        6.000000   1.000  1.000  
1001240000 10A  Orange                             0.600000   1.000  1.000  
1001241000 10A  Orange, juice                      0.600000   1.800  1.000  
1001241001 10A  Orange, juice-babyfood             0.600000   1.800  1.000  
1001242000 10A  Orange, peel                       0.600000   1.000  1.000  
1001369000 10A  Tangerine                          0.600000   1.000  1.000  
1001370000 10A  Tangerine, juice                   0.600000   2.300  1.000  
1002197000 10B  Kumquat                            0.600000   1.000  1.000  
1002199000 10B  Lemon                              0.600000   1.000  1.000  
1002200000 10B  Lemon, juice                       0.600000   2.000  1.000  
1002200001 10B  Lemon, juice-babyfood              0.600000   2.000  1.000  
1002201000 10B  Lemon, peel                        0.600000   1.000  1.000  
1002206000 10B  Lime                               0.600000   1.000  1.000  
1002207000 10B  Lime, juice                        0.600000   2.000  1.000  
1002207001 10B  Lime, juice-babyfood               0.600000   2.000  1.000  
1003180000 10C  Grapefruit                         0.600000   1.000  1.000  
1003181000 10C  Grapefruit, juice                  0.600000   2.100  1.000  
1003307000 10C  Pummelo                            0.600000   1.000  1.000  
1100007000 11   Apple, fruit with peel             0.700000   1.000  1.000  
1100008000 11   Apple, peeled fruit                0.700000   1.000  1.000  
1100008001 11   Apple, peeled fruit-babyfood       0.700000   1.000  1.000  
1100009000 11   Apple, dried                       0.700000   8.000  1.000  
1100009001 11   Apple, dried-babyfood              0.700000   8.000  1.000  
1100010000 11   Apple, juice                       0.700000   1.300  1.000  
1100010001 11   Apple, juice-babyfood              0.700000   1.300  1.000  
1100011000 11   Apple, sauce                       0.700000   1.000  1.000  
1100011001 11   Apple, sauce-babyfood              0.700000   1.000  1.000  
1100129000 11   Crabapple                          0.700000   1.000  1.000  
1100173500 11   Goji berry                         2.500000   1.000  1.000  
1100210000 11   Loquat                             0.700000   1.000  1.000  
1100266000 11   Pear                               0.700000   1.000  1.000  
1100266001 11   Pear-babyfood                      0.700000   1.000  1.000  
1100267000 11   Pear, dried                        0.700000   6.250  1.000  
1100268000 11   Pear, juice                        0.700000   1.000  1.000  
1100268001 11   Pear, juice-babyfood               0.700000   1.000  1.000  
1100310000 11   Quince                             0.700000   1.000  1.000  
1201090000 12A  Cherry                             4.500000   1.000  1.000  
1201090001 12A  Cherry-babyfood                    4.500000   1.000  1.000  
1201091000 12A  Cherry, juice                      4.500000   1.500  1.000  
1201091001 12A  Cherry, juice-babyfood             4.500000   1.500  1.000  
1202012000 12B  Apricot                            4.500000   1.000  1.000  
1202012001 12B  Apricot-babyfood                   4.500000   1.000  1.000  
1202013000 12B  Apricot, dried                     4.500000   6.000  1.000  
1202014000 12B  Apricot, juice                     4.500000   1.000  1.000  
1202014001 12B  Apricot, juice-babyfood            4.500000   1.000  1.000  
1202230000 12B  Nectarine                          4.500000   1.000  1.000  
1202260000 12B  Peach                              4.500000   1.000  1.000  
1202260001 12B  Peach-babyfood                     4.500000   1.000  1.000  
1202261000 12B  Peach, dried                       4.500000   7.000  1.000  
1202261001 12B  Peach, dried-babyfood              4.500000   7.000  1.000  
1202262000 12B  Peach, juice                       4.500000   1.000  1.000  
1202262001 12B  Peach, juice-babyfood              4.500000   1.000  1.000  
1203285000 12C  Plum                               4.500000   1.000  1.000  
1203285001 12C  Plum-babyfood                      4.500000   1.000  1.000  
1203286000 12C  Plum, prune, fresh                 4.500000   1.000  1.000  
1203286001 12C  Plum, prune, fresh-babyfood        4.500000   1.000  1.000  
1203287000 12C  Plum, prune, dried                 4.500000   5.000  1.000  
1203287001 12C  Plum, prune, dried-babyfood        4.500000   5.000  1.000  
1203288000 12C  Plum, prune, juice                 4.500000   1.400  1.000  
1203288001 12C  Plum, prune, juice-babyfood        4.500000   1.400  1.000  
1302057000 13B  Blueberry                          3.000000   1.000  1.000  
1302057001 13B  Blueberry-babyfood                 3.000000   1.000  1.000  
1302136000 13B  Currant                            3.000000   1.000  1.000  
1302137000 13B  Currant, dried                     3.000000   1.000  1.000  
1302149000 13B  Elderberry                         3.000000   1.000  1.000  
1302174000 13B  Gooseberry                         3.000000   1.000  1.000  
1302191000 13B  Huckleberry                        3.000000   1.000  1.000  
1304175000 13D  Grape                              1.300000   1.000  1.000  
1304176000 13D  Grape, juice                       1.300000   1.200  1.000  
1304176001 13D  Grape, juice-babyfood              1.300000   1.200  1.000  
1304179000 13D  Grape, wine and sherry             1.300000   1.000  1.000  
1304195000 13D  Kiwifruit, fuzzy                   1.300000   1.000  1.000  
1307130000 13G  Cranberry                          0.300000   1.000  1.000  
1307130001 13G  Cranberry-babyfood                 0.300000   1.000  1.000  
1307131000 13G  Cranberry, dried                   0.300000   1.000  1.000  
1307132000 13G  Cranberry, juice                   0.300000   1.100  1.000  
1307132001 13G  Cranberry, juice-babyfood          0.300000   1.100  1.000  
1307359000 13G  Strawberry                         0.400000   1.000  1.000  
1307359001 13G  Strawberry-babyfood                0.400000   1.000  1.000  
1307360000 13G  Strawberry, juice                  0.400000   1.000  1.000  
1307360001 13G  Strawberry, juice-babyfood         0.400000   1.000  1.000  
1400003000 14   Almond                             0.250000   1.000  1.000  
1400003001 14   Almond-babyfood                    0.250000   1.000  1.000  
1400004000 14   Almond, oil                        0.250000   1.000  1.000  
1400004001 14   Almond, oil-babyfood               0.250000   1.000  1.000  
1400059000 14   Brazil nut                         0.250000   1.000  1.000  
1400068000 14   Butternut                          0.250000   1.000  1.000  
1400081000 14   Cashew                             0.250000   1.000  1.000  
1400092000 14   Chestnut                           0.250000   1.000  1.000  
1400155000 14   Hazelnut                           0.250000   1.000  1.000  
1400156000 14   Hazelnut, oil                      0.250000   1.000  1.000  
1400185000 14   Hickory nut                        0.250000   1.000  1.000  
1400213000 14   Macadamia nut                      0.250000   1.000  1.000  
1400269000 14   Pecan                              0.250000   1.000  1.000  
1400282000 14   Pistachio                          0.250000   1.000  1.000  
1400391000 14   Walnut                             0.250000   1.000  1.000  
1500127000 15   Corn, sweet                        1.500000   1.000  1.000  
1500127001 15   Corn, sweet-babyfood               1.500000   1.000  1.000  
2003128000 20C  Cottonseed, oil                    0.300000   1.000  1.000  
2003128001 20C  Cottonseed, oil-babyfood           0.300000   1.000  1.000  
3100044000 31   Beef, meat                         0.020000   1.000  1.000  
3100044001 31   Beef, meat-babyfood                0.020000   1.000  1.000  
3100045000 31   Beef, meat, dried                  0.020000   1.920  1.000  
3100046000 31   Beef, meat byproducts              0.200000   1.000  1.000  
3100046001 31   Beef, meat byproducts-babyfood     0.200000   1.000  1.000  
3100047000 31   Beef, fat                          0.020000   1.000  1.000  
3100047001 31   Beef, fat-babyfood                 0.020000   1.000  1.000  
3100048000 31   Beef, kidney                       0.200000   1.000  1.000  
3100049000 31   Beef, liver                        0.200000   1.000  1.000  
3100049001 31   Beef, liver-babyfood               0.200000   1.000  1.000  
3200169000 32   Goat, meat                         0.020000   1.000  1.000  
3200170000 32   Goat, meat byproducts              0.200000   1.000  1.000  
3200171000 32   Goat, fat                          0.020000   1.000  1.000  
3200172000 32   Goat, kidney                       0.200000   1.000  1.000  
3200173000 32   Goat, liver                        0.200000   1.000  1.000  
3300189000 33   Horse, meat                        0.020000   1.000  1.000  
3400291000 34   Pork, skin                         0.020000   1.000  1.000  
3400292000 34   Pork, meat byproducts              0.020000   1.000  1.000  
3400292001 34   Pork, meat byproducts-babyfood     0.020000   1.000  1.000  
3400294000 34   Pork, kidney                       0.020000   1.000  1.000  
3400295000 34   Pork, liver                        0.020000   1.000  1.000  
3500339000 35   Sheep, meat                        0.020000   1.000  1.000  
3500339001 35   Sheep, meat-babyfood               0.020000   1.000  1.000  
3500340000 35   Sheep, meat byproducts             0.200000   1.000  1.000  
3500341000 35   Sheep, fat                         0.020000   1.000  1.000  
3500341001 35   Sheep, fat-babyfood                0.020000   1.000  1.000  
3500342000 35   Sheep, kidney                      0.200000   1.000  1.000  
3500343000 35   Sheep, liver                       0.200000   1.000  1.000  
3600222000 36   Milk, fat                          0.010000   1.000  1.000  
3600222001 36   Milk, fat-baby food/infant formu   0.010000   1.000  1.000  
3600223000 36   Milk, nonfat solids                0.010000   1.000  1.000  
3600223001 36   Milk, nonfat solids-baby food/in   0.010000   1.000  1.000  
3600224000 36   Milk, water                        0.010000   1.000  1.000  
3600224001 36   Milk, water-babyfood/infant form   0.010000   1.000  1.000  
3600225001 36   Milk, sugar (lactose)-baby food/   0.010000   1.000  1.000  
3800221000 38   Meat, game                         0.020000   1.000  1.000  
4000094000 40   Chicken, liver                     0.020000   1.000  1.000  
4000095000 40   Chicken, meat byproducts           0.020000   1.000  1.000  
4000095001 40   Chicken, meat byproducts-babyfoo   0.020000   1.000  1.000  
4000097000 40   Chicken, skin                      0.020000   1.000  1.000  
4000097001 40   Chicken, skin-babyfood             0.020000   1.000  1.000  
5000383000 50   Turkey, liver                      0.020000   1.000  1.000  
5000383001 50   Turkey, liver-babyfood             0.020000   1.000  1.000  
5000384000 50   Turkey, meat byproducts            0.020000   1.000  1.000  
5000384001 50   Turkey, meat byproducts-babyfood   0.020000   1.000  1.000  
5000386000 50   Turkey, skin                       0.020000   1.000  1.000  
5000386001 50   Turkey, skin-babyfood              0.020000   1.000  1.000  
6000302000 60   Poultry, other, liver              0.020000   1.000  1.000  
6000303000 60   Poultry, other, meat byproducts    0.020000   1.000  1.000  
6000305000 60   Poultry, other, skin               0.020000   1.000  1.000  
7000145000 70   Egg, whole                         0.020000   1.000  1.000  
7000145001 70   Egg, whole-babyfood                0.020000   1.000  1.000  
7000146000 70   Egg, white                         0.020000   1.000  1.000  
7000146001 70   Egg, white (solids)-babyfood       0.020000   1.000  1.000  
7000147000 70   Egg, yolk                          0.020000   1.000  1.000  
7000147001 70   Egg, yolk-babyfood                 0.020000   1.000  1.000  
8601000000 86A  Water, direct, all sources         0.395000   1.000  1.000  
8602000000 86B  Water, indirect, all sources       0.395000   1.000  1.000  
9500001000 O    Acerola                            2.500000   1.000  1.000  
9500016000 O    Artichoke, globe                   1.500000   1.000  1.000  
9500020000 O    Avocado                            0.600000   1.000  1.000  
9500023000 O    Banana                             4.000000   1.000  1.000  
9500023001 O    Banana-babyfood                    4.000000   1.000  1.000  
9500024000 O    Banana, dried                      4.000000   3.900  1.000  
9500024001 O    Banana, dried-babyfood             4.000000   3.900  1.000  
9500074000 O    Canistel                           0.600000   1.000  1.000  
9500115000 O    Coffee, roasted bean               0.200000   1.000  1.000  
9500116000 O    Coffee, instant                    0.500000   1.000  1.000  
9500151000 O    Feijoa                             2.500000   1.000  1.000  
9500177000 O    Grape, leaves                      1.300000   1.000  1.000  
9500178000 O    Grape, raisin                      3.000000   1.000  1.000  
9500183000 O    Guava                              2.500000   1.000  1.000  
9500183001 O    Guava-babyfood                     2.500000   1.000  1.000  
9500188000 O    Hop                               10.000000   1.000  1.000  
9500209000 O    Longan                            13.000000   1.000  1.000  
9500211000 O    Lychee                            13.000000   1.000  1.000  
9500212000 O    Lychee, dried                     13.000000   1.850  1.000  
9500215000 O    Mango                              0.600000   1.000  1.000  
9500215001 O    Mango-babyfood                     0.600000   1.000  1.000  
9500216000 O    Mango, dried                       0.600000   1.000  1.000  
9500217000 O    Mango, juice                       0.600000   1.000  1.000  
9500217001 O    Mango, juice-babyfood              0.600000   1.000  1.000  
9500245000 O    Papaya                             2.500000   1.000  1.000  
9500245001 O    Papaya-babyfood                    2.500000   1.000  1.000  
9500246000 O    Papaya, dried                      2.500000   1.800  1.000  
9500247000 O    Papaya, juice                      2.500000   1.500  1.000  
9500252000 O    Passionfruit                       2.500000   1.000  1.000  
9500252001 O    Passionfruit-babyfood              2.500000   1.000  1.000  
9500253000 O    Passionfruit, juice                2.500000   1.000  1.000  
9500253001 O    Passionfruit, juice-babyfood       2.500000   1.000  1.000  
9500277000 O    Persimmon                          2.500000   1.000  1.000  
9500279000 O    Pineapple                          0.300000   1.000  1.000  
9500279001 O    Pineapple-babyfood                 0.300000   1.000  1.000  
9500280000 O    Pineapple, dried                   0.300000   5.000  1.000  
9500281000 O    Pineapple, juice                   0.300000   1.700  1.000  
9500281001 O    Pineapple, juice-babyfood          0.300000   1.700  1.000  
9500283000 O    Plantain                           4.000000   1.000  1.000  
9500284000 O    Plantain, dried                    4.000000   3.900  1.000  
9500289000 O    Pomegranate                        0.500000   1.000  1.000  
9500333000 O    Sapote, Mamey                      0.600000   1.000  1.000  
9500351000 O    Spanish lime                      13.000000   1.000  1.000  
9500358000 O    Starfruit                          2.500000   1.000  1.000  
9500398000 O    Watercress                         2.000000   1.000  1.000  

Attachment 2:  Acute Results File 

U.S. EPA                                                    Ver. 3.16, 03-08-d
DEEM-FCID ACUTE Analysis for SPIROTETRAMAT               NHANES 2003-2008 2-Day
Residue file: updated SPIROTETRAMAT__ACUTE__21 Dec 2012.R08
    Adjustment factor #2 used.
Analysis Date: 12-21-2012/13:26:05    Residue file dated: 12-21-2012/11:35:33
RAC/FF intake summed over 24 hours
Run Comment: "+ emp proc fact"
===============================================================================

Summary calculations--per capita:

                   95th Percentile      99th Percentile     99.9th Percentile
                   Exposure   % aRfD    Exposure   % aRfD    Exposure   % aRfD 
                  ---------- --------  ---------- --------  ---------- --------
Total US Population:
                    0.066115     6.61    0.114460    11.45    0.209645    20.96 
All Infants:
                    0.137642    13.76    0.220433    22.04    0.419080    41.91 
Children 1-2:
                    0.155241    15.52    0.282877    28.29    0.447437    44.74 
Children 3-5:
                    0.125606    12.56    0.181399    18.14    0.276584    27.66 
Children 6-12:
                    0.075624     7.56    0.115439    11.54    0.186328    18.63 
Youth 13-19:
                    0.046354     4.64    0.071801     7.18    0.117196    11.72 
Adults 20-49:
                    0.053000     5.30    0.075334     7.53    0.118274    11.83 
Adults 50-99:
                    0.050326     5.03    0.074209     7.42    0.107443    10.74 
Female 13-49:
             0.052999     5.30    0.078727     7.87    0.118210    11.82 
Attachment 3:  Average Field Trial Residues and Processing Factors Used in the Chronic Assessment
                                       
Table A.3.  Summary of Residues and Processing Factors used in the Chronic Assessment[1].  
                                     Crop
                                   Commodity
                                 Residue (ppm)
                               Processing Factor
                                      %CT
                                   Comments
Potato and Sweet Potato
                                      RAC
                                     0.171
                                       1
                                      100
Potato residues translated to sweet potato using HED SOP 2000.1.  Other members of crop group 1C used tolerance-level residues.  Future assessments could incorporate average field-trial (FT) residues for these commodities.  Average FT residue.  Used 150 OD formulation because had highest average residue.  Memo, G. Kramer, 17-APR-2008; D339694.

                                     Dried
                                      1.6
                                       1
                                      100
Tolerance-level residue.  Processing factor set to 1 because separate tolerance established in 40 CFR §180.641.
Onion
                                      RAC
                                     0.80
                                       1
                                      100
HED-recommended tolerance-level residue.  

                                     Dried
                                     0.80
                                      9.0
                                      100
HED-recommended tolerance-level residue.  DEEM 7.81 default processing factor.
Head Lettuce
                                      RAC
                                     0.605
                                       1
                                      100
Average FT residue.  Used 100 OD formulation because had highest average residue.  Memo, G. Kramer, 17-APR-2008; D339694.
Leaf Lettuce
                                      RAC
                                     0.882
                                       1
                                      100
Average FT residue.  Used 100 OD formulation because had highest average residue.  Memo, G. Kramer, 17-APR-2008; D339694.
Spinach
                                      RAC
                                     2.496
                                       1
                                      100
Average FT residue.  Used 240 SC formulation because had highest average residue.  Memo, G. Kramer, 17-APR-2008; D339694.
Edible-podded beans (6A)
                                      RAC
                                     0.444
                                       1
                                      100
Average snap bean FT residue.  Used OD formulation because had highest average residue.  Memo, G. Kramer, 23-DEC-2010; D362952.
Edible-podded peas (6A)
                                      RAC
                                     1.28
                                       1
                                      100
Average snow pea FT residue.  Used SC formulation because had highest average residue.  Memo, G. Kramer, 23-DEC-2010; D362952.
Succulent shelled beans (6B)
                                      RAC
                                     0.243
                                       1
                                      100
Average lima bean FT residue.  Used OD formulation because had highest average residue.  Memo, G. Kramer, 23-DEC-2010; D362952.
Succulent shelled peas (6B)
                                      RAC
                                     0.583
                                       1
                                      100
Average garden pea FT residue.  Used OD formulation because had highest average residue.  Memo, G. Kramer, 23-DEC-2010; D362952.
Tomato
                                      RAC
                                      2.5
                                       1
                                      100
Tolerance-level residue.  

                                     Dried
                                      2.5
                                      12
                                      100
Tolerance-level residue.  Empirical processing factor from Memo, G. Kramer, 17-APR-2008; D339694.

                                     Juice
                                      2.5
                                      0.9
                                      100
Tolerance-level residue.  Empirical processing factor from Memo, G. Kramer, 17-APR-2008; D339694.

                                     Paste
                                      2.5
                                       1
                                      100
Tolerance-level residue.  Processing factor set to 1 because a separate tolerance was not required based on the available processing data and the tolerance-level values were used in the assessment (Memo, G. Kramer, 17-APR-2008; D339694).

                                     Puree
                                      2.5
                                       1
                                      100
Tolerance-level residue.  Processing factor set to 1 because a separate tolerance was not required based on the available processing data and the tolerance-level values were used in the assessment (Memo, G. Kramer, 17-APR-2008; D339694).
Grapefruit
                                      RAC
                                     0.60
                                       1
                                      100
Tolerance-level residue.  

                                     Juice
                                     0.60
                                      2.1
                                      100
Tolerance-level residue.  DEEM 7.81 default processing factor.
Lemon
                                      RAC
                                     0.60
                                       1
                                      100
Tolerance-level residue.  

                                     Juice
                                     0.60
                                      2.0
                                      100
Tolerance-level residue.  DEEM 7.81 default processing factor.
Lime
                                      RAC
                                     0.60
                                       1
                                      100
Tolerance-level residue.  

                                     Juice
                                     0.60
                                      2.0
                                      100
Tolerance-level residue.  DEEM 7.81 default processing factor.
Orange
                                      RAC
                                     0.60
                                       1
                                      100
Tolerance-level residue.  

                                     Juice
                                     0.60
                                      0.4
                                      100
Tolerance-level residue.  Empirical processing factor from Memo, G. Kramer, 17-APR-2008; D339694.
Tangerine
                                      RAC
                                     0.60
                                       1
                                      100
Tolerance-level residue.  

                                     Juice
                                     0.60
                                      2.3
                                      100
Tolerance-level residue.  DEEM 7.81 default processing factor.
Apple
                                      RAC
                                     0.152
                                       1
                                      100
Average FT residue.  Used concentrated 150 OD formulation because had highest average residue.   Memo, G. Kramer, 17-APR-2008; D339694.

                                     Dried
                                     0.152
                                       1
                                      100
Average FT residue.  Empirical processing factor from Memo, G. Kramer, 17-APR-2008; D339694.

                                     Juice
                                     0.152
                                      0.4
                                      100
Average FT residue.  Empirical processing factor from Memo, G. Kramer, 17-APR-2008; D339694.

                                     Sauce
                                     0.152
                                      0.1
                                      100
Average FT residue.  Empirical processing factor from Memo, G. Kramer, 17-APR-2008; D339694.
Pear
                                      RAC
                                     0.205
                                       1
                                      100
Average FT residue.  Used concentrated 150 OD formulation because had highest average residue.  Memo, G. Kramer, 17-APR-2008; D339694.

                                     Dried
                                     0.205
                                     6.25
                                      100
Average FT residue.  DEEM 7.81 default processing factor.

                                     Juice
                                     0.205
                                       1
                                      100
Average FT residue.
Apricot
                                      RAC
                                     4.50
                                       1
                                      100
Tolerance-level residue.  

                                     Dried
                                     4.50
                                      6.0
                                      100
Tolerance-level residue.  DEEM 7.81 default processing factor.

                                     Juice
                                     4.50
                                       1
                                      100
Tolerance-level residue.  
Cherry
                                      RAC
                                     1.480
                                       1
                                      100
Average FT residue.  Used dilute 150 OD formulation because had highest average residue.   Memo, G. Kramer, 17-APR-2008; D339694.

                                     Juice
                                     1.480
                                      1.5
                                      100
Average FT residue.  DEEM 7.81 default processing factor.
Peach
                                      RAC
                                     0.692
                                       1
                                      100
Average FT residue.  Used dilute 150 OD formulation because had highest average residue.   Memo, G. Kramer, 17-APR-2008; D339694.  

                                     Dried
                                     0.692
                                      7.0
                                      100
Average FT residue.  DEEM 7.81 default processing factor.

                                     Juice
                                     0.692
                                       1
                                      100
Average FT residue.  

                                      RAC
                                      4.5
                                       1
                                      100
Tolerance-level residue.  
Plum, prune
                                     Dried
                                      4.5
                                       1
                                      100
Tolerance-level residue.  Processing factor set to 1 because a separate tolerance was not required based on the available processing data and the tolerance-level values were used in the assessment (Memo, G. Kramer, 17-APR-2008; D339694).

                                     Juice
                                      4.5
                                      1.4
                                      100
Tolerance-level residue.  DEEM 7.81 default processing factor.
Cranberry
                                      RAC
                                     0.30
                                       1
                                      100
HED-recommended tolerance-level residue.  

                                     Juice
                                     0.30
                                      1.1
                                      100
HED-recommended tolerance-level residue.  DEEM 7.81 default processing factor.
Grape
                                      RAC
                                     0.412
                                       1
                                      100
Average FT residue.  Used OD formulation because had highest average residue.   Memo, G. Kramer, 17-APR-2008; D339694.

                                     Juice
                                     0.412
                                     0.66
                                      100
Average FT residue.  Empirical processing factor from Memo, G. Kramer, 17-APR-2008; D339694.

                                    Raisin
                                      3.0
                                       1
                                      100
Tolerance-level residue.  Processing factor set to 1 because separate tolerance established in 40 CFR §180.641.
Beef, meat
                                     Dried
                                     0.02
                                     1.92
                                      100
Tolerance-level residue.  DEEM 7.81 default processing factor.
Banana and plantain
                                      RAC
                                      1.3
                                       1
                                      100
Average FT residue from Memo, G. Kramer, 26-MAR-2013; D398856.

                                     Dried
                                      1.3
                                      3.9
                                      100
Average FT residue.  DEEM 7.81 default processing factor.
Feijoa
                                      RAC
                                      2.5
                                       1
                                      100
This tolerance is incorrect in the 40CFR.  Since the HED-recommended tolerance of 2.5 ppm (Memo, J. Van Alstine et al., 22-DEC-2010; D368785) is greater than the tolerance in the 40 CFR, the higher HED-recommended tolerance has been used.
Lychee, dried
                                      RAC
                                     13.0
                                       1
                                      100
Tolerance-level residue.

                                     Dried
                                     13.0
                                     1.85
                                      100
Tolerance-level residue.  DEEM 7.81 default processing factor.
Papaya
                                      RAC
                                      2.5
                                       1
                                      100
Tolerance-level residue, as included 40CFR.  Although the HED-recommended tolerance is 0.35 ppm, 2.5 ppm was used to be conservative.  HED has notified RD that the tolerance should be updated to reflect the HED-recommended tolerance of 0.35 ppm.  DEEM 7.81 default processing factor.

                                     Dried
                                      2.5
                                      1.8
                                      100
Tolerance-level residue, as included 40CFR.  DEEM 7.81 default processing factor.

                                     Juice
                                      2.5
                                      1.5
                                      100
Tolerance-level residue, as included 40CFR.  DEEM 7.81 default processing factor.
Persimmon
                                      RAC
                                      2.5
                                       1
                                      100
This tolerance was recommended in Memo, J. Van Alstine et al., 22-DEC-2010 (D368785), however it was excluded from the 40CFR.  It has been included in the assessment since a tolerance was recommended.  
Pineapple
                                      RAC
                                     0.30
                                       1
                                      100
HED-recommended tolerance-level residue.  

                                     Dried
                                     0.30
                                      5.0
                                      100
HED-recommended tolerance-level residue.  DEEM 7.81 default processing factor.

                                     Juice
                                     0.30
                                     0.72
                                      100
HED-recommended tolerance-level residue.  Empirical processing factor from Memo, G. Kramer, 26-MAR-2013; D398856.
Spanish lime 
                                      RAC
                                     13.0
                                       1
                                      100
This tolerance is incorrect in the 40CFR.  Since the HED-recommended tolerance of 13.0 ppm (Memo, J. Van Alstine et al., 22-DEC-2010; D368785) is greater than the tolerance in the 40 CFR, the higher HED-recommended tolerance has been used.
[1] Tolerance-level residues were assumed for the remaining commodities with tolerances that are not included in this table.  
Attachment 4:  Chronic Food plus Water Residue Input File

Filename: C:\Documents and Settings\jlangsda\My Documents\Chemicals\Spirotetramat\2012 RCC\Dietary\Sent to Reviewers\updated to include Kiwi\updated SPIROTETRAMAT__CHRONIC__21 Dec 2012.R08
Chemical: Spirotetramat
RfD(Chronic): .05 mg/kg bw/day  NOEL(Chronic): 0 mg/kg bw/day
RfD(Acute): 1 mg/kg bw/day  NOEL(Acute):  0 mg/kg bw/day
Date created/last modified: 12-21-2012/11:38:57       Program ver. 3.16, 03-08-d
-----------------------------------------------------------------------------------
   EPA     Crop                                   Def Res     Adj.Factors   Comment
   Code     Grp  Commodity Name                    (ppm)       #1    #2   
---------- ---- -------------------------------  ----------  ------ ------  -------
0103015000 1CD  Arrowroot, flour                   0.600000   1.000  1.000  
0103015001 1CD  Arrowroot, flour-babyfood          0.600000   1.000  1.000  
0103017000 1CD  Artichoke, Jerusalem               0.600000   1.000  1.000  
0103082000 1CD  Cassava                            0.600000   1.000  1.000  
0103082001 1CD  Cassava-babyfood                   0.600000   1.000  1.000  
0103139000 1CD  Dasheen, corm                      0.600000   1.000  1.000  
0103166000 1CD  Ginger                             0.600000   1.000  1.000  
0103166001 1CD  Ginger-babyfood                    0.600000   1.000  1.000  
0103167000 1CD  Ginger, dried                      0.600000   1.000  1.000  
0103296000 1C   Potato, chips                      0.171000   1.000  1.000  
0103297000 1C   Potato, dry (granules/ flakes)     1.600000   1.000  1.000  
0103297001 1C   Potato, dry (granules/ flakes)-b   1.600000   1.000  1.000  
0103298000 1C   Potato, flour                      1.600000   1.000  1.000  
0103298001 1C   Potato, flour-babyfood             1.600000   1.000  1.000  
0103299000 1C   Potato, tuber, w/peel              0.171000   1.000  1.000  
0103299001 1C   Potato, tuber, w/peel-babyfood     0.171000   1.000  1.000  
0103300000 1C   Potato, tuber, w/o peel            0.171000   1.000  1.000  
0103300001 1C   Potato, tuber, w/o peel-babyfood   0.171000   1.000  1.000  
0103366000 1CD  Sweet potato                       0.171000   1.000  1.000  
0103366001 1CD  Sweet potato-babyfood              0.171000   1.000  1.000  
0103371000 1CD  Tanier, corm                       0.600000   1.000  1.000  
0103387000 1CD  Turmeric                           0.600000   1.000  1.000  
0103406000 1CD  Yam, true                          0.600000   1.000  1.000  
0103407000 1CD  Yam bean                           0.600000   1.000  1.000  
0301165000 3A   Garlic, bulb                       0.800000   1.000  1.000  
0301165001 3A   Garlic, bulb-babyfood              0.800000   1.000  1.000  
0301237000 3A   Onion, bulb                        0.800000   1.000  1.000  
0301237001 3A   Onion, bulb-babyfood               0.800000   1.000  1.000  
0301238000 3A   Onion, bulb, dried                 0.800000   9.000  1.000  
0301238001 3A   Onion, bulb, dried-babyfood        0.800000   9.000  1.000  
0301338000 3A   Shallot, bulb                      0.800000   1.000  1.000  
0302103000 3B   Chive, fresh leaves                0.800000   1.000  1.000  
0302198000 3B   Leek                               0.800000   1.000  1.000  
0302239000 3B   Onion, green                       0.800000   1.000  1.000  
0302338500 3B   Shallot, fresh leaves              0.800000   1.000  1.000  
0401005000 4A   Amaranth, leafy                    9.000000   1.000  1.000  
0401018000 4A   Arugula                            9.000000   1.000  1.000  
0401104000 4A   Chrysanthemum, garland             9.000000   1.000  1.000  
0401133000 4A   Cress, garden                      9.000000   1.000  1.000  
0401134000 4A   Cress, upland                      9.000000   1.000  1.000  
0401138000 4A   Dandelion, leaves                  9.000000   1.000  1.000  
0401150000 4A   Endive                             9.000000   1.000  1.000  
0401204000 4A   Lettuce, head                      0.605000   1.000  1.000  
0401205000 4A   Lettuce, leaf                      0.882000   1.000  1.000  
0401248000 4A   Parsley, leaves                    9.000000   1.000  1.000  
0401313000 4A   Radicchio                          9.000000   1.000  1.000  
0401355000 4A   Spinach                            2.496000   1.000  1.000  
0401355001 4A   Spinach-babyfood                   2.496000   1.000  1.000  
0402076000 4B   Cardoon                            9.000000   1.000  1.000  
0402085000 4B   Celery                             9.000000   1.000  1.000  
0402085001 4B   Celery-babyfood                    9.000000   1.000  1.000  
0402086000 4B   Celery, juice                      9.000000   1.000  1.000  
0402087000 4B   Celtuce                            9.000000   1.000  1.000  
0402152000 4B   Fennel, Florence                   9.000000   1.000  1.000  
0402322000 4B   Rhubarb                            9.000000   1.000  1.000  
0402367000 4B   Swiss chard                        9.000000   1.000  1.000  
0501061000 5A   Broccoli                           2.500000   1.000  1.000  
0501061001 5A   Broccoli-babyfood                  2.500000   1.000  1.000  
0501062000 5A   Broccoli, Chinese                  2.500000   1.000  1.000  
0501064000 5A   Brussels sprouts                   2.500000   1.000  1.000  
0501069000 5A   Cabbage                            2.500000   1.000  1.000  
0501071000 5A   Cabbage, Chinese, napa             2.500000   1.000  1.000  
0501072000 5A   Cabbage, Chinese, mustard          2.500000   1.000  1.000  
0501083000 5A   Cauliflower                        2.500000   1.000  1.000  
0501196000 5A   Kohlrabi                           2.500000   1.000  1.000  
0502063000 5B   Broccoli raab                      8.000000   1.000  1.000  
0502070000 5B   Cabbage, Chinese, bok choy         8.000000   1.000  1.000  
0502117000 5B   Collards                           8.000000   1.000  1.000  
0502194000 5B   Kale                               8.000000   1.000  1.000  
0502229000 5B   Mustard greens                     8.000000   1.000  1.000  
0502318000 5B   Rape greens                        8.000000   1.000  1.000  
0502389000 5B   Turnip, greens                     8.000000   1.000  1.000  
0600347000 6    Soybean, seed                      5.000000   1.000  1.000  
0600349000 6    Soybean, soy milk                  5.000000   1.000  1.000  
0600349001 6    Soybean, soy milk-babyfood or in   5.000000   1.000  1.000  
0600350000 6    Soybean, oil                       5.000000   1.000  1.000  
0600350001 6    Soybean, oil-babyfood              5.000000   1.000  1.000  
0601043000 6A   Bean, snap, succulent              0.444000   1.000  1.000  
0601043001 6A   Bean, snap, succulent-babyfood     0.444000   1.000  1.000  
0601257000 6A   Pea, edible podded, succulent      1.280000   1.000  1.000  
0601349500 6AB  Soybean, vegetable                 5.000000   1.000  1.000  
0602031000 6B   Bean, broad, succulent             0.243000   1.000  1.000  
0602033000 6B   Bean, cowpea, succulent            0.243000   1.000  1.000  
0602037000 6B   Bean, lima, succulent              0.243000   1.000  1.000  
0602255000 6B   Pea, succulent                     0.583000   1.000  1.000  
0602255001 6B   Pea, succulent-babyfood            0.583000   1.000  1.000  
0602259000 6B   Pea, pigeon, succulent             0.583000   1.000  1.000  
0603030000 6C   Bean, black, seed                  2.500000   1.000  1.000  
0603032000 6C   Bean, broad, seed                  2.500000   1.000  1.000  
0603034000 6C   Bean, cowpea, seed                 2.500000   1.000  1.000  
0603035000 6C   Bean,  great northern, seed        2.500000   1.000  1.000  
0603036000 6C   Bean, kidney, seed                 2.500000   1.000  1.000  
0603038000 6C   Bean, lima, seed                   2.500000   1.000  1.000  
0603039000 6C   Bean, mung, seed                   2.500000   1.000  1.000  
0603040000 6C   Bean, navy, seed                   2.500000   1.000  1.000  
0603041000 6C   Bean, pink, seed                   2.500000   1.000  1.000  
0603042000 6C   Bean, pinto, seed                  2.500000   1.000  1.000  
0603098000 6C   Chickpea, seed                     2.500000   1.000  1.000  
0603098001 6C   Chickpea, seed-babyfood            2.500000   1.000  1.000  
0603099000 6C   Chickpea, flour                    2.500000   1.000  1.000  
0603182000 6C   Guar, seed                         2.500000   1.000  1.000  
0603182001 6C   Guar, seed-babyfood                2.500000   1.000  1.000  
0603203000 6C   Lentil, seed                       2.500000   1.000  1.000  
0603256000 6C   Pea, dry                           2.500000   1.000  1.000  
0603256001 6C   Pea, dry-babyfood                  2.500000   1.000  1.000  
0603258000 6C   Pea, pigeon, seed                  2.500000   1.000  1.000  
0603348000 6C   Soybean, flour                     5.000000   1.000  1.000  
0603348001 6C   Soybean, flour-babyfood            5.000000   1.000  1.000  
0801374000 8A   Tomatillo                          2.500000   1.000  1.000  
0801375000 8A   Tomato                             2.500000   1.000  1.000  
0801375001 8A   Tomato-babyfood                    2.500000   1.000  1.000  
0801376000 8A   Tomato, paste                      2.500000   1.000  1.000  
0801376001 8A   Tomato, paste-babyfood             2.500000   1.000  1.000  
0801377000 8A   Tomato, puree                      2.500000   1.000  1.000  
0801377001 8A   Tomato, puree-babyfood             2.500000   1.000  1.000  
0801378000 8A   Tomato, dried                      2.500000  12.000  1.000  
0801378001 8A   Tomato, dried-babyfood             2.500000  12.000  1.000  
0801379000 8A   Tomato, juice                      2.500000   0.900  1.000  
0801380000 8A   Tomato, Tree                       2.500000   1.000  1.000  
0802148000 8BC  Eggplant                           2.500000   1.000  1.000  
0802234000 8BC  Okra                               2.500000   1.000  1.000  
0802270000 8B   Pepper, bell                       2.500000   1.000  1.000  
0802270001 8B   Pepper, bell-babyfood              2.500000   1.000  1.000  
0802271000 8B   Pepper, bell, dried                2.500000   1.000  1.000  
0802271001 8B   Pepper, bell, dried-babyfood       2.500000   1.000  1.000  
0802272000 8BC  Pepper, nonbell                    2.500000   1.000  1.000  
0802272001 8BC  Pepper, nonbell-babyfood           2.500000   1.000  1.000  
0802273000 8BC  Pepper, nonbell, dried             2.500000   1.000  1.000  
0901075000 9A   Cantaloupe                         0.300000   1.000  1.000  
0901187000 9A   Honeydew melon                     0.300000   1.000  1.000  
0901399000 9A   Watermelon                         0.300000   1.000  1.000  
0901400000 9A   Watermelon, juice                  0.300000   1.000  1.000  
0902021000 9B   Balsam pear                        0.300000   1.000  1.000  
0902088000 9B   Chayote, fruit                     0.300000   1.000  1.000  
0902102000 9B   Chinese waxgourd                   0.300000   1.000  1.000  
0902135000 9B   Cucumber                           0.300000   1.000  1.000  
0902308000 9B   Pumpkin                            0.300000   1.000  1.000  
0902309000 9B   Pumpkin, seed                      0.300000   1.000  1.000  
0902356000 9B   Squash, summer                     0.300000   1.000  1.000  
0902356001 9B   Squash, summer-babyfood            0.300000   1.000  1.000  
0902357000 9B   Squash, winter                     0.300000   1.000  1.000  
0902357001 9B   Squash, winter-babyfood            0.300000   1.000  1.000  
1001106000 10A  Citron                             0.600000   1.000  1.000  
1001107000 10A  Citrus hybrids                     0.600000   1.000  1.000  
1001108000 10A  Citrus, oil                        6.000000   1.000  1.000  
1001240000 10A  Orange                             0.600000   1.000  1.000  
1001241000 10A  Orange, juice                      0.600000   0.400  1.000  
1001241001 10A  Orange, juice-babyfood             0.600000   0.400  1.000  
1001242000 10A  Orange, peel                       0.600000   1.000  1.000  
1001369000 10A  Tangerine                          0.600000   1.000  1.000  
1001370000 10A  Tangerine, juice                   0.600000   2.300  1.000  
1002197000 10B  Kumquat                            0.600000   1.000  1.000  
1002199000 10B  Lemon                              0.600000   1.000  1.000  
1002200000 10B  Lemon, juice                       0.600000   2.000  1.000  
1002200001 10B  Lemon, juice-babyfood              0.600000   2.000  1.000  
1002201000 10B  Lemon, peel                        0.600000   1.000  1.000  
1002206000 10B  Lime                               0.600000   1.000  1.000  
1002207000 10B  Lime, juice                        0.600000   2.000  1.000  
1002207001 10B  Lime, juice-babyfood               0.600000   2.000  1.000  
1003180000 10C  Grapefruit                         0.600000   1.000  1.000  
1003181000 10C  Grapefruit, juice                  0.600000   2.100  1.000  
1003307000 10C  Pummelo                            0.600000   1.000  1.000  
1100007000 11   Apple, fruit with peel             0.152000   1.000  1.000  
1100008000 11   Apple, peeled fruit                0.152000   1.000  1.000  
1100008001 11   Apple, peeled fruit-babyfood       0.152000   1.000  1.000  
1100009000 11   Apple, dried                       0.152000   1.000  1.000  
1100009001 11   Apple, dried-babyfood              0.152000   1.000  1.000  
1100010000 11   Apple, juice                       0.152000   0.400  1.000  
1100010001 11   Apple, juice-babyfood              0.152000   0.400  1.000  
1100011000 11   Apple, sauce                       0.152000   0.100  1.000  
1100011001 11   Apple, sauce-babyfood              0.152000   0.100  1.000  
1100129000 11   Crabapple                          0.700000   1.000  1.000  
1100173500 11   Goji berry                         2.500000   1.000  1.000  
1100210000 11   Loquat                             0.700000   1.000  1.000  
1100266000 11   Pear                               0.205000   1.000  1.000  
1100266001 11   Pear-babyfood                      0.205000   1.000  1.000  
1100267000 11   Pear, dried                        0.205000   6.250  1.000  
1100268000 11   Pear, juice                        0.205000   1.000  1.000  
1100268001 11   Pear, juice-babyfood               0.205000   1.000  1.000  
1100310000 11   Quince                             0.700000   1.000  1.000  
1201090000 12A  Cherry                             1.480000   1.000  1.000  
1201090001 12A  Cherry-babyfood                    1.480000   1.000  1.000  
1201091000 12A  Cherry, juice                      1.480000   1.500  1.000  
1201091001 12A  Cherry, juice-babyfood             1.480000   1.500  1.000  
1202012000 12B  Apricot                            4.500000   1.000  1.000  
1202012001 12B  Apricot-babyfood                   4.500000   1.000  1.000  
1202013000 12B  Apricot, dried                     4.500000   6.000  1.000  
1202014000 12B  Apricot, juice                     4.500000   1.000  1.000  
1202014001 12B  Apricot, juice-babyfood            4.500000   1.000  1.000  
1202230000 12B  Nectarine                          4.500000   1.000  1.000  
1202260000 12B  Peach                              0.692000   1.000  1.000  
1202260001 12B  Peach-babyfood                     0.692000   1.000  1.000  
1202261000 12B  Peach, dried                       0.692000   7.000  1.000  
1202261001 12B  Peach, dried-babyfood              0.692000   7.000  1.000  
1202262000 12B  Peach, juice                       0.692000   1.000  1.000  
1202262001 12B  Peach, juice-babyfood              0.692000   1.000  1.000  
1203285000 12C  Plum                               4.500000   1.000  1.000  
1203285001 12C  Plum-babyfood                      4.500000   1.000  1.000  
1203286000 12C  Plum, prune, fresh                 4.500000   1.000  1.000  
1203286001 12C  Plum, prune, fresh-babyfood        4.500000   1.000  1.000  
1203287000 12C  Plum, prune, dried                 4.500000   1.000  1.000  
1203287001 12C  Plum, prune, dried-babyfood        4.500000   1.000  1.000  
1203288000 12C  Plum, prune, juice                 4.500000   1.400  1.000  
1203288001 12C  Plum, prune, juice-babyfood        4.500000   1.400  1.000  
1302057000 13B  Blueberry                          3.000000   1.000  1.000  
1302057001 13B  Blueberry-babyfood                 3.000000   1.000  1.000  
1302136000 13B  Currant                            3.000000   1.000  1.000  
1302137000 13B  Currant, dried                     3.000000   1.000  1.000  
1302149000 13B  Elderberry                         3.000000   1.000  1.000  
1302174000 13B  Gooseberry                         3.000000   1.000  1.000  
1302191000 13B  Huckleberry                        3.000000   1.000  1.000  
1304175000 13D  Grape                              0.412000   1.000  1.000  
1304176000 13D  Grape, juice                       0.412000   0.660  1.000  
1304176001 13D  Grape, juice-babyfood              0.412000   0.660  1.000  
1304179000 13D  Grape, wine and sherry             0.412000   1.000  1.000  
1304195000 13D  Kiwifruit, fuzzy                   1.300000   1.000  1.000  
1307130000 13G  Cranberry                          0.300000   1.000  1.000  
1307130001 13G  Cranberry-babyfood                 0.300000   1.000  1.000  
1307131000 13G  Cranberry, dried                   0.300000   1.000  1.000  
1307132000 13G  Cranberry, juice                   0.300000   1.100  1.000  
1307132001 13G  Cranberry, juice-babyfood          0.300000   1.100  1.000  
1307359000 13G  Strawberry                         0.400000   1.000  1.000  
1307359001 13G  Strawberry-babyfood                0.400000   1.000  1.000  
1307360000 13G  Strawberry, juice                  0.400000   1.000  1.000  
1307360001 13G  Strawberry, juice-babyfood         0.400000   1.000  1.000  
1400003000 14   Almond                             0.250000   1.000  1.000  
1400003001 14   Almond-babyfood                    0.250000   1.000  1.000  
1400004000 14   Almond, oil                        0.250000   1.000  1.000  
1400004001 14   Almond, oil-babyfood               0.250000   1.000  1.000  
1400059000 14   Brazil nut                         0.250000   1.000  1.000  
1400068000 14   Butternut                          0.250000   1.000  1.000  
1400081000 14   Cashew                             0.250000   1.000  1.000  
1400092000 14   Chestnut                           0.250000   1.000  1.000  
1400155000 14   Hazelnut                           0.250000   1.000  1.000  
1400156000 14   Hazelnut, oil                      0.250000   1.000  1.000  
1400185000 14   Hickory nut                        0.250000   1.000  1.000  
1400213000 14   Macadamia nut                      0.250000   1.000  1.000  
1400269000 14   Pecan                              0.250000   1.000  1.000  
1400282000 14   Pistachio                          0.250000   1.000  1.000  
1400391000 14   Walnut                             0.250000   1.000  1.000  
1500127000 15   Corn, sweet                        1.500000   1.000  1.000  
1500127001 15   Corn, sweet-babyfood               1.500000   1.000  1.000  
2003128000 20C  Cottonseed, oil                    0.300000   1.000  1.000  
2003128001 20C  Cottonseed, oil-babyfood           0.300000   1.000  1.000  
3100044000 31   Beef, meat                         0.020000   1.000  1.000  
3100044001 31   Beef, meat-babyfood                0.020000   1.000  1.000  
3100045000 31   Beef, meat, dried                  0.020000   1.920  1.000  
3100046000 31   Beef, meat byproducts              0.200000   1.000  1.000  
3100046001 31   Beef, meat byproducts-babyfood     0.200000   1.000  1.000  
3100047000 31   Beef, fat                          0.020000   1.000  1.000  
3100047001 31   Beef, fat-babyfood                 0.020000   1.000  1.000  
3100048000 31   Beef, kidney                       0.200000   1.000  1.000  
3100049000 31   Beef, liver                        0.200000   1.000  1.000  
3100049001 31   Beef, liver-babyfood               0.200000   1.000  1.000  
3200169000 32   Goat, meat                         0.020000   1.000  1.000  
3200170000 32   Goat, meat byproducts              0.200000   1.000  1.000  
3200171000 32   Goat, fat                          0.020000   1.000  1.000  
3200172000 32   Goat, kidney                       0.200000   1.000  1.000  
3200173000 32   Goat, liver                        0.200000   1.000  1.000  
3300189000 33   Horse, meat                        0.020000   1.000  1.000  
3400291000 34   Pork, skin                         0.020000   1.000  1.000  
3400292000 34   Pork, meat byproducts              0.020000   1.000  1.000  
3400292001 34   Pork, meat byproducts-babyfood     0.020000   1.000  1.000  
3400294000 34   Pork, kidney                       0.020000   1.000  1.000  
3400295000 34   Pork, liver                        0.020000   1.000  1.000  
3500339000 35   Sheep, meat                        0.020000   1.000  1.000  
3500339001 35   Sheep, meat-babyfood               0.020000   1.000  1.000  
3500340000 35   Sheep, meat byproducts             0.200000   1.000  1.000  
3500341000 35   Sheep, fat                         0.020000   1.000  1.000  
3500341001 35   Sheep, fat-babyfood                0.020000   1.000  1.000  
3500342000 35   Sheep, kidney                      0.200000   1.000  1.000  
3500343000 35   Sheep, liver                       0.200000   1.000  1.000  
3600222000 36   Milk, fat                          0.010000   1.000  1.000  
3600222001 36   Milk, fat-baby food/infant formu   0.010000   1.000  1.000  
3600223000 36   Milk, nonfat solids                0.010000   1.000  1.000  
3600223001 36   Milk, nonfat solids-baby food/in   0.010000   1.000  1.000  
3600224000 36   Milk, water                        0.010000   1.000  1.000  
3600224001 36   Milk, water-babyfood/infant form   0.010000   1.000  1.000  
3600225001 36   Milk, sugar (lactose)-baby food/   0.010000   1.000  1.000  
3800221000 38   Meat, game                         0.020000   1.000  1.000  
4000094000 40   Chicken, liver                     0.020000   1.000  1.000  
4000095000 40   Chicken, meat byproducts           0.020000   1.000  1.000  
4000095001 40   Chicken, meat byproducts-babyfoo   0.020000   1.000  1.000  
4000097000 40   Chicken, skin                      0.020000   1.000  1.000  
4000097001 40   Chicken, skin-babyfood             0.020000   1.000  1.000  
5000383000 50   Turkey, liver                      0.020000   1.000  1.000  
5000383001 50   Turkey, liver-babyfood             0.020000   1.000  1.000  
5000384000 50   Turkey, meat byproducts            0.020000   1.000  1.000  
5000384001 50   Turkey, meat byproducts-babyfood   0.020000   1.000  1.000  
5000386000 50   Turkey, skin                       0.020000   1.000  1.000  
5000386001 50   Turkey, skin-babyfood              0.020000   1.000  1.000  
6000302000 60   Poultry, other, liver              0.020000   1.000  1.000  
6000303000 60   Poultry, other, meat byproducts    0.020000   1.000  1.000  
6000305000 60   Poultry, other, skin               0.020000   1.000  1.000  
7000145000 70   Egg, whole                         0.020000   1.000  1.000  
7000145001 70   Egg, whole-babyfood                0.020000   1.000  1.000  
7000146000 70   Egg, white                         0.020000   1.000  1.000  
7000146001 70   Egg, white (solids)-babyfood       0.020000   1.000  1.000  
7000147000 70   Egg, yolk                          0.020000   1.000  1.000  
7000147001 70   Egg, yolk-babyfood                 0.020000   1.000  1.000  
8601000000 86A  Water, direct, all sources         0.395000   1.000  1.000  
8602000000 86B  Water, indirect, all sources       0.395000   1.000  1.000  
9500001000 O    Acerola                            2.500000   1.000  1.000  
9500016000 O    Artichoke, globe                   1.500000   1.000  1.000  
9500020000 O    Avocado                            0.600000   1.000  1.000  
9500023000 O    Banana                             1.300000   1.000  1.000  
9500023001 O    Banana-babyfood                    1.300000   1.000  1.000  
9500024000 O    Banana, dried                      1.300000   3.900  1.000  
9500024001 O    Banana, dried-babyfood             1.300000   3.900  1.000  
9500074000 O    Canistel                           0.600000   1.000  1.000  
9500115000 O    Coffee, roasted bean               0.200000   1.000  1.000  
9500116000 O    Coffee, instant                    0.500000   1.000  1.000  
9500151000 O    Feijoa                             2.500000   1.000  1.000  
9500177000 O    Grape, leaves                      0.412000   1.000  1.000  
9500178000 O    Grape, raisin                      3.000000   1.000  1.000  
9500183000 O    Guava                              2.500000   1.000  1.000  
9500183001 O    Guava-babyfood                     2.500000   1.000  1.000  
9500188000 O    Hop                               10.000000   1.000  1.000  
9500209000 O    Longan                            13.000000   1.000  1.000  
9500211000 O    Lychee                            13.000000   1.000  1.000  
9500212000 O    Lychee, dried                     13.000000   1.850  1.000  
9500215000 O    Mango                              0.600000   1.000  1.000  
9500215001 O    Mango-babyfood                     0.600000   1.000  1.000  
9500216000 O    Mango, dried                       0.600000   1.000  1.000  
9500217000 O    Mango, juice                       0.600000   1.000  1.000  
9500217001 O    Mango, juice-babyfood              0.600000   1.000  1.000  
9500245000 O    Papaya                             2.500000   1.000  1.000  
9500245001 O    Papaya-babyfood                    2.500000   1.000  1.000  
9500246000 O    Papaya, dried                      2.500000   1.800  1.000  
9500247000 O    Papaya, juice                      2.500000   1.500  1.000  
9500252000 O    Passionfruit                       2.500000   1.000  1.000  
9500252001 O    Passionfruit-babyfood              2.500000   1.000  1.000  
9500253000 O    Passionfruit, juice                2.500000   1.000  1.000  
9500253001 O    Passionfruit, juice-babyfood       2.500000   1.000  1.000  
9500277000 O    Persimmon                          2.500000   1.000  1.000  
9500279000 O    Pineapple                          0.300000   1.000  1.000  
9500279001 O    Pineapple-babyfood                 0.300000   1.000  1.000  
9500280000 O    Pineapple, dried                   0.300000   5.000  1.000  
9500281000 O    Pineapple, juice                   0.300000   0.720  1.000  
9500281001 O    Pineapple, juice-babyfood          0.300000   0.720  1.000  
9500283000 O    Plantain                           1.300000   1.000  1.000  
9500284000 O    Plantain, dried                    1.300000   3.900  1.000  
9500289000 O    Pomegranate                        0.500000   1.000  1.000  
9500333000 O    Sapote, Mamey                      0.600000   1.000  1.000  
9500351000 O    Spanish lime                      13.000000   1.000  1.000  
9500358000 O    Starfruit                          2.500000   1.000  1.000  
9500398000 O    Watercress                         2.000000   1.000  1.000  

 

 

 Attachment 5:  Chronic Results File

U.S. EPA                                                        Ver. 3.16, 03-08-d
DEEM-FCID Chronic analysis for SPIROTETRAMAT               NHANES 2003-2008 2-day
Residue file name: C:\Documents and Settings\jlangsda\My Documents\Chemicals\Spirotetramat\2012 RCC\Dietary\Sent to Reviewers\updated to include Kiwi\updated SPIROTETRAMAT__CHRONIC__21 Dec 2012.R08
                                                     Adjustment factor #2 used.
Analysis Date 12-21-2012/13:21:54     Residue file dated: 12-21-2012/11:38:57
Reference dose (RfD, Chronic) = .05 mg/kg bw/day
===============================================================================
                    Total exposure by population subgroup
-------------------------------------------------------------------------------

                                                    Total Exposure
                                         -----------------------------------
          Population                         mg/kg             Percent of   
           Subgroup                       body wt/day             Rfd       
--------------------------------------   -------------       ----------------
Total US Population                         0.017785                35.6%
Hispanic                                    0.018737                37.5%
Non-Hisp-White                              0.017748                35.5%
Non-Hisp-Black                              0.015575                31.1%
Non-Hisp-Other                              0.021071                42.1%
Nursing Infants                             0.016243                32.5%
Non-Nursing Infants                         0.046105                92.2%
Female 13+ PREG                             0.016541                33.1%
Children 1-6                                0.032850                65.7%
Children 7-12                               0.018046                36.1%
Male 13-19                                  0.012837                25.7%
Female 13-19/NP                             0.013480                27.0%
Male 20+                                    0.015660                31.3%
Female 20+/NP                               0.016866                33.7%
Seniors 55+                                 0.016343                32.7%
All Infants                                 0.036886                73.8%
Female 13-50                                0.015912                31.8%
Children 1-2                                0.038038                76.1%
Children 3-5                                0.030925                61.9%
Children 6-12                               0.019418                38.8%
Youth 13-19                                 0.013149                26.3%
Adults 20-49                                0.016159                32.3%
Adults 50-99                                0.016494                33.0%
Female 13-49                                0.015902                31.8%

-------------------------------------------------------------------------------