Document ID: EPA-HQ-OPP-2005-0497-0033
Agency: epa
Document Type: Supporting & Related Material
Title: 
Posted Date: 2006-08-23T04:00Z

Reader’s Guide to the Propiconazole E-Docket # OPP-2005-0497

EPA has created this document to provide an organizational structure to
the Propiconazole E-docket.  The docket index lists the caption entries
sequentially, while this document lists them by subject matter.  The
Agency is providing the “Readers Guide” to allow the reader to more
easily access and navigate the various entries contained in the
Propiconazole E-docket.

Federal Register Notice, RED, and Fact Sheet  

Docket Entry 1.	Federal Register Notice: Propiconazole; Reregistration
Eligibility Decision (RED) Document; Notice of Availability.  August 16,
2006.  

This document announces the availability of the Propiconazole RED in the
public docket and on   HYPERLINK "http://www.regulations.gov" 
www.regulations.gov .

Docket Entry 2.	Reader’s Guide to the Propiconazole RED # EPA-HQ-

			OPP-2005-0497 

This document provides a list of the documents in the Propiconazole RED
docket, with a brief explanation of the purpose of each document. 

	

Docket Entry 3.	Propiconazole Reregistration Eligibility 							Decision
Document 

	

This is the Reregistration Eligibility Decision (RED) document for
propiconazole.  This document summarizes the Agency’s review of
required data for propiconaole, risk assessment conclusions, and
regulatory decision for this pesticide active ingredient.

Docket Entry 4.	Propiconazole Fact Sheet 

This document summarizes the Reregistration Eligibility Decision (RED)
for propiconazole.

Technical Support Documents for Propiconazole 

Docket Entry 5.	Propiconazole:  Phase4, HED Chapter of the
Reregistration Eligibility Decision Document (RED).  June 28, 2006. 

This document is the Agency’s final human health risk assessment
supporting the propiconazole RED.  This document focuses on risks
associated with conventional agricultural uses of propiconazole and also
provides an aggregate risk assessment to support a safety finding under
the Food Quality Protection Act.

 

Docket Entry 6.	Propiconazole: Phase IV, revised Occupational and
Residential Exposure Assessment for the Reregistration Eligibility
Decision Document (RED).  June 15, 2006. 

This document is the Agency’s evaluation of potential exposure and
risk to workers using propiconazole in agriculture and to adults and
children who may be exposed through residential uses of propiconazole on
lawns and in gardens.  

Docket Entry 7	Propiconazole:  Revised Occupational and Residential
Exposure Assessment of the Antimicrobial Uses to Support the
Reregistration Eligibility Decision (RED) Document.  February 1, 2006. 

This document is the Agency’s evaluation of potential exposure and
risk from antimicrobial uses of propiconazole as either a wood
preservative or a material preservative.  

Docket Entry 8.	Propiconazole:  Amendment to the Propiconazole
Reregistration Eligibility Decision (RED) Document for Children’s Post
application Exposure Treated Structures.  June 20, 2006.

This document is an amendment to the preceding document dated February
1, 2006 and is an exposure and risk assessment of potential residential
exposure to propiconazole used as a wood preservative on lumber in decks
and playsets. 

	

Docket Entry 9.	Propiconazole Revised Acute and Chronic Dietary Exposure
Assessment for Reregistration Eligibility [sic] Decision (RED). Phase 4
June 7, 2006. 

This document summarizes potential exposure and risk to the general
population and various population subgroups from propiconazole residues
in food and drinking water. 

Docket Entry 10.	Propiconazole (122101):  Reregistration Eligibility
Decision (RED) Document; Revised Residue Chemistry Considerations.  June
15, 2006. 

This document summarizes EPA’s evaluation of the numerous residue 
chemistry studies required to support continued registration of
propiconazole.  This document contains information on the metabolism of
propiconazole in plants and animals, residue levels in treated crops,
livestock, and processed food commodities, and recommendations for
reassessment of propiconazole tolerances. 

Docket Entry 11.	Environmental Fate and Effects Division Revised RED for
the Reregistration of Propiconazole.  June 29, 2006. 

This document is EPA’s final ecological risk assessment for the
propiconazole RED. 

Docket Entry 12.	Terrestrial Plant Runoff Risk Assessment for
Propiconazole on Turf Using PRZM.  July 14, 2006.   

This document provides additional characterization of the terrestrial
plant risk assessment for propiconazole. 

Docket Entry 13.	Revised Drinking Water Assessment of Propiconazole. 
June 7, 2006.  

This document summarizes the Agency’s findings regarding potential
levels of propiconazole residues in drinking water.  

Technical Support Documents for the Free Triazole Degradates

Docket Entry 14.	Meeting Summary:  EPA/FDA Joint Teleconference on July
11, 2006 to Discuss 1,2,4-Triazole (Free Triazole) as a Common
Metabolite of Triazole Derivative Fungicides and Anastrozole, a Drug. 
July 18, 2006. 

This document summarizes a final conference call between EPA and FDA to
discuss potential co-ocurring exposure to free triazoles from both
triazole pesticides and use of triazole-derivative drugs.  

Docket Entry 15.	EPA 1,2,4-Triazole Consult Response.  Memo from John
Lazor, Director, FDA Division of Clinical Pharmacology 4, to Debra
Edwards, Director, Special Review and Reregistration Division.  May 19,
2006.

This document is FDA’s response to a request for information about
triazole-derivative drugs that could potentially metabolize to the free
triazole compounds 1,2,4-triazole, triazole alanine, and triazole acetic
acid. 

Docket Entry 16.	Response to Triazole Task Force Comments on the FQPA
Drinking Water Assessment for 1,2,4-Triazole (!,2,4-T), Triazole alanine
(TA), and Triazole Acetic Acid (TAA).  June 15, 2006. 

This document is EPA’s response to comments received from and industry
group, the Triazole Task Force, on the Agency’s drinking water
assessment for the free triazole degradates of triazole fungicides.

Documents on Propiconazole Use and Useage

Docket Entry 17. 	Usage Report Package in Support of Reregistration for
the Fungicide Propiconazole (122101).  April 26, 2006.

This document summarizes readily available information on the use of
propiconazole on turf. 

Docket Entry 18.	Usage Report Package in Support of Reregistration for
the Fungicide  Propiconazole (122101) DP # 327918.  April 4, 2006.

This document summarizes readily available information on the use of
propiconazole on agricultural crops.