Document ID: EPA-HQ-OPP-2014-0679-0014
Agency: epa
Document Type: Supporting & Related Material
Title: 
Posted Date: 2017-05-18T04:00Z

FIRST AID
If swallowed

     Call a poison control center or doctor immediately for treatment advice.
     Have person sip a glass of water if able to swallow.
     Do not induce vomiting unless told to do so by a poison control center or doctor.
     Do not give anything to an unconscious person.
If on skin
     Take off contaminated clothing.
     Rinse skin immediately with plenty of soap and water for 15-20 minutes.
     Call a poison control center or doctor for treatment advice.
Have the product container or label with you when calling a poison control center or doctor, or going for treatment.
                                HOT LINE NUMBER
          For 24-Hour Medical Emergency Assistance (Human or Animal) 
                             Call 1-888-484-7546.
                                       
For Chemical Emergency, Spill, Leak, Fire or Accident, Call CHEMTREC 1-800-424-9300.
                                       

                                     GROUP
 28
 INSECTICIDE
                                       
                                       

CYCLANILIPROLE 50SL 

INSECTICIDE

ACTIVE INGREDIENT: Cyclaniliprole*	4.55%
OTHER INGREDIENTS:	95.45%
Total	100.0%

*3-bromo-N-[2-bromo-4-chloro-6[[(1-cyclopropylethyl)amino]carbonyl]phenyl]-1-(3-chloro-2-pyridinyl) 
-1H-3-pyrazole-5-carboxamide 

Contains 0.42 pounds Cyclaniliprole per Gallon (50 grams per liter)

KEEP OUT OF REACH OF CHILDREN

CAUTION

See side panel for additional precautionary statements.

Read entire label carefully and use only as directed.

ISK Biosciences Corporation
7470 Auburn Road, Suite A
Concord, Ohio 44077 U.S.A.

EPA Reg. No. 	71512-XXX 		EPA Est. No. 

Net Contents:
  
PRECAUTIONARY STATEMENTS

HAZARDS TO HUMANS AND DOMESTIC ANIMALS
                                    CAUTION

Harmful if swallowed or absorbed through skin. Avoid contact with skin, eyes or clothing.  Wash thoroughly with soap and water after handling and before eating, drinking, chewing gum, using tobacco or using the toilet. Remove and wash contaminated clothing before reuse.  
Personal Protective Equipment (PPE)
Applicators and other handlers must wear long-sleeved shirt and long pants, socks, shoes, and chemical resistant gloves made of any waterproof material.
Follow manufacturer's instructions for cleaning/ maintaining PPE. If no such instructions for washables, use detergent and hot water. Keep and wash PPE separately from other laundry.
Engineering Control Statements
When handlers use closed systems, enclosed cabs, or aircraft in a manner that meets the requirements listed in the Worker Protection Standard (WPS) for agricultural pesticides [40 CFR 170.240(d)(4-6)], the handler PPE requirements may be reduced or modified as specified in the WPS.
User Safety Recommendations
Users should:
 Wash hands before eating, drinking, chewing gum, using tobacco or using the toilet.
 Remove clothing/PPE immediately if pesticide gets inside.  Then wash thoroughly and put on clean clothing. 
 Remove PPE immediately after handling this product.  Wash the outside of gloves before removing.  As soon as possible, wash thoroughly and change into clean clothing.  

ENVIRONMENTAL HAZARDS

This product is highly toxic to bees and other pollinating insects exposed to direct treatment on blooming crops or weeds. Do not apply this product or allow it to drift to blooming crops or weeds while bees or other pollinating insects are foraging the treatment area. This product is toxic to bees and other pollinating insects exposed to direct treatment. Do not apply this product while bees or other pollinating insects are actively visiting the treatment area. 

DO NOT apply directly to water, or to areas where surface water is present or to intertidal areas below the mean high water mark. DO NOT contaminate waters when disposing of equipment washwater or rinsate.  DO NOT apply when weather conditions favor drift from the treated areas. Drift and runoff may be hazardous to aquatic organisms in water adjacent to treated areas.
AVOIDING SPRAY DRIFT AT THE APPLICATION SITE IS THE RESPONSIBILITY OF THE APPLICATOR. The interaction of many equipment and weather-related factors determine the potential for spray drift. The applicator is responsible for considering all these factors when making decisions. Where states have more stringent regulations, they must be observed.
STORAGE AND DISPOSAL

DO NOT contaminate water, food or feed by storage or disposal.  
PESTICIDE STORAGE: Store in original container, in a secured, dry, cool place separate from fertilizer, food, and feed. Avoid cross-contamination with other pesticides.
PESTICIDE DISPOSAL: Pesticide wastes may be hazardous.  Improper disposal of excess pesticide, spray mixture or rinsate is a violation of Federal law. If these wastes cannot be disposed of by use according to label instructions, contact your State Pesticide or Environmental Control Agency or the Hazardous Waste representative at the nearest EPA Regional Office for guidance.
CONTAINER DISPOSAL: Nonrefillable container (equal to or less than 5 gallons). DO NOT reuse or refill this container. Triple rinse container (or equivalent) promptly after emptying. Triple rinse as follows: Empty the remaining contents into application equipment or a mix tank and drain for 10 seconds after the flow begins to drip. Fill the container (1/4) full with water and recap. Shake for 10 seconds. Pour rinsate into application equipment or a mix tank or store rinsate for later use or disposal.  Drain for 10 seconds after the flow begins to drip. Repeat this procedure two more times. Then offer for recycling if available, or puncture and dispose of in a sanitary landfill, or by incineration or, if allowed by state and local authorities, by burning. If burned, stay out of smoke.
Nonrefillable container (greater than 5 gallons). DO NOT reuse or refill this container.  Triple rinse container (or equivalent) promptly after emptying. Triple rinse as follows: Empty the remaining contents into application equipment or a mix tank. Fill the container (1/4) full with water. Recap and tighten closures. Tip container on its side and roll it back and forth, ensuring at least one complete revolution, for 30 seconds. Stand the container on its end and tip it back and forth several times. Turn the container over onto its other end and tip it back and forth several times. Empty rinsate into application equipment or a mix tank or store rinsate for later use or disposal. Repeat this procedure two more times. Then offer for recycling if available, or puncture and dispose of in a sanitary landfill, or by incineration or, if allowed by state and local authorities, by burning.  If burned, stay out of smoke.

DIRECTIONS FOR USE

It is a violation of Federal law to use this product in a manner inconsistent with its labeling.
DO NOT apply this product in a way that will contact workers or other persons, either directly or through drift. Only protected handlers may be in the area during application. For any requirements specific to your State or Tribe, consult the agency responsible for pesticide regulation.
AGRICULTURAL USE REQUIREMENTS
--------------------------------------------------------------------------------
Use this product only in accordance with its labeling and with the Worker Protection Standard, 40 CFR Part 170. This Standard contains requirements for the protection of agricultural workers on farms, forests, nurseries, and greenhouses and handlers of agricultural pesticides. It contains requirements for training, decontamination, notification, and emergency assistance. It also contains specific instructions and exceptions pertaining to the statements on this label about personal protective equipment (PPE), and restricted-entry interval. The requirements in this box only apply to uses of this product that are covered by the Worker Protection Standard.
--------------------------------------------------------------------------------
DO NOT enter or allow worker entry into treated areas during the Restricted Entry Interval (REI) of twelve (12) hours. 
--------------------------------------------------------------------------------
PPE required for early entry into treated areas that is permitted under the Worker Protection Standard and that involves contact with anything that has been treated, such as plants, soil, or water, are: coveralls, chemical resistant gloves made of any waterproof material, shoes plus socks.

FAILURE TO FOLLOW THE USE DIRECTIONS AND PRECAUTIONS ON THIS LABEL MAY RESULT IN PLANT INJURY OR POOR PEST CONTROL.

GENERAL INFORMATION
CYCLANILIPROLE is an insecticide with foliar activity.  CYCLANILIPROLE must be applied in scheduled protective programs and used in rotation with products with a different mode of action.  

MIXING AND SPRAYING
CYCLANILIPROLE 50SL can be used effectively in dilute or concentrate sprays. Thorough, uniform coverage is essential for pest control.  
NOTE: Slowly invert container several times to assure uniform mixture of formulation before adding this product to the spray tank.
Dosage rates on this label indicate fluid ounces of CYCLANILIPROLE 50SL per acre, unless otherwise stated. Under conditions favorable for disease development, the highest rate specified and shortest application interval should be used.  
CYCLANILIPROLE 50SL may be applied with all types of spray equipment normally used for ground, chemigation through sprinkler irrigation and aerial applications.
The required amount of CYCLANILIPROLE 50SL should be added slowly into the spray tank during filling. With concentrate sprays, pre-mix the required amount of CYCLANILIPROLE 50SL in a clean container and add to the spray tank as it is being filled. Keep agitator running when filling spray tank and during spray operations. DO NOT allow spray mixture to stand overnight or for prolonged periods. Prepare only the amount of spray required for immediate use. Spraying equipment should be thoroughly cleaned immediately after the application.
Apply CYCLANILIPROLE 50SL in sufficient water to obtain adequate coverage of the foliage. Gallonage to be used will vary with crop and amount of plant growth.  Spray volume will usually range from 20 to 100 gallons per acre (200 to 1000 liters per hectare) for dilute sprays, and 5 to 10 gallons per acre (50 to 100 liters per hectare) for concentrate ground and aerial sprays. For aerial applications, apply CYCLANILIPROLE 50SL in a minimum of 5 gallons of water per acre. For application through sprinkler irrigation systems see application and calibration instructions below.
TANK MIX COMPATIBILITY
CYCLANILIPROLE 50SL is physically compatible (no nozzle or screen blockage) with many products recommended for control of diseases and insects on crops and other additives. Read and follow all manufacturer's label recommendations for the tank mix companion product. It is the applicator's responsibility to ensure that the companion product is EPA approved for use on the intended crop. CYCLANILIPROLE 50SL is generally compatible with other insecticides, fungicides, adjuvants, fertilizers and micronutrient products provided sufficient free water is available for dispersion of all the tank mix products. The use of methylated seed oil (MSO) or other high quality adjuvant at a rate of 0.025% to 0.1% on volume to volume basis may improve performance under extreme conditions. However, not all crop varieties have been tested with all possible tank mix combinations. Thus the combination should be tested for crop safety on a small portion of the crop to ensure that a phytotoxic response will not occur. In addition, the physical compatibility of CYCLANILIPROLE 50SL with tank mix partners must be evaluated before use. Conduct a jar test with intended tank-mix pesticides prior to preparation of large volumes. Use the following procedure: 1) Pour the recommended proportions of the products into a suitable container of water, 2) Mix thoroughly and 3) Allow to stand for 5 minutes. If the combination remains mixed or can be re-mixed readily, it is considered physically compatible. Any physical incompatibility in the jar test indicates that CYCLANILIPROLE 50SL should not be used in the tank-mix. 
ROTATIONAL CROP RESTRICTIONS
Crops on this label may be planted immediately after the last treatment.  Do not plant other crops not registered for this product within 30 days after the last application. 
INTEGRATED PEST MANAGEMENT
CYCLANILIPROLE 50SL is an excellent insect pest control agent when used according to label directions for control of labeled insect pests.  CYCLANILIPROLE 50SL is recommended for use as part of an Integrated Pest Management (IPM) program, which may include the use of pest-resistant crop varieties, cultural practices, crop rotation, biological control agents, pest scouting and pest forecasting systems aimed at preventing economic pest damage. Practices known to reduce insect pest development should be followed. Consult your state cooperative extension service or local agricultural authorities for additional IPM strategies established in your area. CYCLANILIPROLE 50SL may be used in State Agricultural Extension advisory (insect pest forecasting) programs that recommend application timing based upon environmental factors that favor insect pest development.

RESISTANCE MANAGEMENT
Some insect pests are known to develop resistance to products used repeatedly for insect control. CYCLANILIPROLE 50SL is an anthranilic diamide in IRAC Group 28 with the mode/target site of action being Ryanodine receptor modulation. An insect pest management program that includes alternation or tank mixes between CYCLANILIPROLE 50SL and other labeled insecticides that have a different mode of action and/or control insect pests not controlled with CYCLANILIPROLE 50SL is essential to prevent insecticide resistant insect pest populations from developing. CYCLANILIPROLE 50SL should not be utilized continuously nor tank mixed with insecticides that have shown to have developed insecticide resistance to the target insect pest.
Since insect pests differ in their potential to develop resistance to insecticides, follow the directions outlined in the "Directions For Use" section of this label for specific resistance management strategies for each crop. Consult with your Federal or State Cooperative Extension Service representatives for guidance on the proper use of CYCLANILIPROLE 50SL in programs that seek to minimize the occurrence of insect pest resistance. 
Follow these instructions to postpone insecticide resistance unless directed otherwise in the specific directions for use sections of this label: 
 Do not use the same mode of action (IRAC group number) on consecutive generations of insect pests.
 Do not apply CYCLANILIPROLE 50SL or other Group 28 insecticide more than 3 times per pest generation to the same insect species on a crop.
 Do not apply CYCLANILIPROLE 50SL or other Group 28 insecticide consecutively more than 2 times within a 30 day period to the same insect species on a crop.
 Application to the next generation of insect pest(s) must be with a product with a different mode of action (non-Group 28 insecticide). 
 Do not use below the labeled rates of CYCLANILIPROLE 50SL alone or in tank mixtures. 
 Applications to the target pest(s) should be made to the most susceptible insect life stages.
 Insecticide use should be based on an IPM program that includes scouting, record keeping, and considers cultural, biological and other chemical control practices.
 Monitor treated pest populations for resistance development.
 Contact your local extension specialist or certified crop advisors for any additional pesticide resistance-management and/or IPM recommendations for the specific site and pest problems in your area.
 More information on insect resistance is available online from the Insecticide Resistance Action Committee (IRAC) at http://www.irac-online.org.

For further information or to report suspected resistance contact ISK Biosciences Corporation at 1-877-706-4640.

BENEFICIAL INSECTS
CYCLANILIPROLE 50SL assists in the conservation of many beneficial insects which are of value in Integrated Pest Management programs. Monitor beneficial and pest insect populations, and make treatment decisions based on locally determined economic thresholds.
APPLICATION AND CALIBRATION TECHNIQUES FOR SPRINKLER IRRIGATION
Apply this product only through center pivot, motorized lateral move, traveling gun, solid set or portable (wheel move, side roll, end tow, or hand move) irrigation system(s). DO NOT apply this product through any other type of irrigation system.
Crop injury, lack of effectiveness, or illegal pesticide residues in the crop can result from non-uniform distribution of treated water.  
If you have questions about calibration, you should contact State Extension Service specialists, equipment manufacturers or other experts.
DO NOT apply CYCLANILIPROLE 50SL through irrigation systems connected to a public water system. "Public water system" means a system for the provision to the public of piped water for human consumption if such system has at least 15 service connections or regularly serves an average of at least 25 individuals daily at least 60 days per year.
Controls for both irrigation water and pesticide injection systems must be functionally interlocked, so as to automatically terminate pesticide injection when the irrigation water pump motor stops. A person knowledgeable of the irrigation system and responsible for its operation shall be present so as to discontinue pesticide injection and make necessary adjustments, should the need arise.
The irrigation water pipeline must be fitted with a functional, automatic, quick-closing check valve to prevent the flow of treated irrigation water back toward the water source. The pipeline must also be fitted with a vacuum relief valve and low-pressure drain, located between the irrigation water pump and the check valve, to prevent back-siphoning of treated irrigation water into the water source.
Always inject CYCLANILIPROLE 50SL into irrigation water after it discharges from the irrigation pump and after it passes through the check valve. Never inject pesticides into the intake line on the suction side of the pump.
Pesticide injection equipment must be fitted with a functional, normally closed, solenoid-operated valve located on the intake side of the injection pump. Interlock this valve to the power system, so as to prevent fluid from being withdrawn from the chemical supply tank when the irrigation system is either automatically or manually turned off.
The pesticide injection pipeline must contain a functional, automatic, quick-closing check valve to prevent the flow of fluid back toward the injection pump. The irrigation line or water pump must include a functional pressure switch that will stop the water pump motor when the water pressure decreases to the point where pesticide distribution is adversely affected.
Spray mixture in the chemical supply tank must be agitated at all times, otherwise settling and uneven application may occur. DO NOT apply when wind speed favors drift beyond the area intended for treatment.
CYCLANILIPROLE 50SL may be used through two basic types of sprinkler irrigation systems as outlined in Sections A and B below.  Determine which type of system is in place, then refer to the appropriate directions provided for each type.

A. Center Pivot, Motorized Lateral Move and Traveling Gun Irrigation Equipment

For injection of pesticides, these continuously moving systems must use a positive displacement injection pump of either diaphragm or piston type, constructed of materials that are compatible with pesticides and capable of being fitted with a system interlock and capable of injection at pressures approximately 2-3 times those encountered within the irrigation water line. Venturi applicator units cannot be used on these systems.
Thoroughly mix recommended amount of this product for acreage to be covered into the same amount of water used during calibration and inject into system continuously for one revolution or run. Mixture in the chemical supply tank must be continuously agitated during the injection run. Shut off injection equipment after one revolution or run, but continue to operate irrigation system until this product has been cleared from the last sprinkler head.
 Solid Set and Portable (Wheel Move, Side Roll, End Tow, or Hand Move) Irrigation Equipment  
    
With stationary systems, an effectively designed in-line venturi applicator unit is preferred which is constructed of materials that are compatible with pesticides; however, a positive-displacement pump can also be used.
Determine acreage covered by sprinkler. Fill tank of injection equipment with water and adjust flow to use contents over a 30 to 45 minute period.  Mix desired amount of CYCLANILIPROLE 50SL for acreage to be covered with water so that the total mixture of this product plus water in the injection tank is equal to the quantity of water used during calibration.
Agitation is recommended. CYCLANILIPROLE 50SL can be injected at the beginning or end of the irrigation cycle or as a separate application.  Stop injection equipment after treatment is completed and continue to operate irrigation system until this product has been cleared from last sprinkler head.

SPRAY DRIFT MANAGEMENT

The interaction of many equipment and weather-related factors determines the potential for spray drift. The applicator is responsible for considering all these factors when making application decisions.

AVOIDING SPRAY DRIFT IS THE RESPONSIBILITY OF THE APPLICATOR.

IMPORTANCE OF DROPLET SIZE
The most effective drift management strategy is to apply the largest droplets which are consistent with pest control objectives. The presence of sensitive species nearby, the environmental conditions, and pest pressure may affect how an applicator balances drift control and coverage. Applying larger droplets reduces drift potential, but will not prevent drift if applications are made improperly or under unfavorable environmental conditions. A droplet size classification system describes the range of droplet sizes produced by spray nozzles. The American Society of Agricultural and Biological Engineers (ASABE) provide a Standard that describes droplet size spectrum categories defined by a number of reference nozzles (fine, coarse, etc.). Droplet spectra resulting from the use of a specific nozzle may also be described in terms of volume mean diameter (VMD). Coarser droplet size spectra have larger VMD's and lower drift potential.
CONTROLLING DROPLET SIZE - GROUND APPLICATION
Nozzle Type - Select a nozzle type that is designed for the intended application. With most nozzle types, narrower spray angles produce larger droplets. The use of low-drift nozzles will reduce drift potential.
Pressure - The lowest spray pressures recommended for the nozzle produce the largest droplets. Higher pressure reduces droplet size and does not improve canopy penetration. When higher flow rates are needed, using a higher-capacity nozzle instead of increasing pressure results in the coarsest droplet spectrum.
Flow Rate/Orifice Size - Using the highest flow rate nozzles (largest orifice) that are consistent with pest control objectives reduces the potential for spray drift. Nozzles with higher rated flows produce coarser droplet spectra.
CONTROLLING DROPLET SIZE - AIRCRAFT
Number of Nozzles -Using the minimum number of nozzles with the highest flow rate that provide uniform coverage will produce a coarser droplet spectrum.
Nozzle Orientation -Orienting nozzles in a manner that minimizes the effects of air shear will produce the coarsest droplet spectra. For some nozzles such as solid stream, pointing the nozzles straight back parallel to the airstream will produce a coarser droplet spectrum than other orientations.
Nozzle Type -Solid stream, or other low drift nozzles produce the coarsest droplet spectra.
Do not apply as a ULV application.
BOOM LENGTH AND HEIGHT
Boom Length (aircraft) -The boom length must not exceed 3/4 of the wing length; using shorter booms decreases drift potential. For helicopters use a boom length and position that prevents droplets from entering the rotor vortices.
Boom Height (aircraft) -Application more than 10 ft. above the canopy increases the potential for spray drift. Applications made at the lowest height consistent with pest control objectives, and the safe operation of the aircraft will reduce the potential for spray drift.
Boom Height (ground) -Applications made at the lowest height consistent with pest control objectives, and that allow the applicator to keep the boom level with the application site and minimize bounce, will reduce the exposure of spray droplets to evaporation and wind and reduce spray drift potential.
WIND
Drift potential increases at wind speeds of less than 3 mph (due to variable direction and inversion potential) or more than
10 mph. However, many factors, including droplet size and equipment type determine drift potential at any given wind speed. AVOID APPLICATIONS DURING GUSTY OR WINDLESS CONDITIONS. Do not make applications when wind speeds are greater than 15 mph.
Note: Local terrain can influence wind patterns. Every applicator must be familiar with local wind patterns and how they affect spray drift.
TEMPERATURE AND HUMIDITY
When making applications in hot and dry conditions, set up equipment to produce larger droplets to reduce effects of evaporation.

SURFACE TEMPERATURE INVERSIONS
Do not make applications into temperature inversions. Drift potential is high during a surface temperature inversion.
Surface inversions restrict vertical air mixing, which causes small-suspended droplets to remain close to the ground and move laterally in a concentrated cloud. Surface inversions are characterized by increasing temperature with altitude and are common on nights with limited cloud cover and light to no wind. They begin to form as the sun sets and often continue into the morning. Their presence can be indicated by ground fog; however, if fog is not present, inversions can also be identified by the movement of smoke from a ground source or an aircraft smoke generator. Smoke that layers and moves laterally in a concentrated cloud (under low wind conditions) indicates a surface inversion, while smoke that moves upward and rapidly dissipates indicates good vertical air mixing.
SHIELDED SPRAYERS
Shielding the boom or individual nozzles can reduce the effects of wind. However, it is the responsibility of the applicator to verify that the shields are preventing drift and not interfering with uniform deposition of the product.
AIR ASSISTED (AIRBLAST) FIELD CROP SPRAYERS
Air assisted field crop sprayers carry droplets to the target via a downward directed air stream. Some may reduce the potential for drift, but if a sprayer is unsuitable for the application and/or set up improperly, high drift potential can result. It is the responsibility of the applicator to determine that a sprayer is suitable for the intended application, is configured properly, and that drift is not occurring.
Note: Air assisted field sprayers can affect product performance by affecting spray coverage and canopy penetration.
Consult the application equipment section of this label to determine if use of an air assisted sprayer is recommended.

DIRECTIONS FOR USE
Crop
Insects
Use Rate
                                Fl. Oz. Product
                                   Per Acre
Instructions
Pome Fruit (Crop Group 11-10)*
Codling moth
Obliquebanded leafroller
Green fruitworm
Redbanded Leafroller
Variegated leafroller
Tufted apple budmoth
Spotted tentiform leafminer
Western tentiform leafminer
White apple leafhopper
European apple sawfly
European corn borer
Oriental Fruit moth
Western flower thrips
Apple Maggot**
Plum Curculio
Pear psylla
Stink bug spp.**

**Suppression Only. Use in conjunction with an effective control program.
16.4 to 22.0 fl oz
                                       
                         (0.054 to 0.072 lb. a.i. /A)
Application Instructions: Thorough coverage is essential to achieve best results. Select a spray volume appropriate for the size of trees and density of foliage. For best results apply 100-200 gallons water per acre.  
Codling Moth Use the high rate of 22 fl oz for heavy infestations, and the low rate of 16.4 fl oz for mild infestations. Make first application just prior to or at the beginning of egg hatch. Applications typically provide 10-14 days of protection. Use pheromone trap catches and local degree day based spray timing advisories to determine the development of each codling moth generation. For effective resistance management make applications of CYCLANILIPROLE 50SL in one codling moth generation before rotating to an insecticide with a different mode of action (Non- Group 28) in the next generation.
Obliquebanded Leafroller Apply in the pink to petal fall stage at first sign of feeding for overwintering larvae. For summer generation apply just prior to or at the beginning of egg hatch. 
Pear Psylla  For best results, apply to first generation nymphs using the high rate of 22 fl oz/A. Performance is enhanced when used with an effective adjuvant.
Stink bugs** CYCLANILIPROLE 50SL provides suppression of stink bug NYMPHS ONLY. Use as a part of an Integrated Pest Management (IPM) program and target the most susceptible life stages and application timings. Use in conjunction with other modes of action and effective control products. Performance is enhanced when used with an effective adjuvant. For best results, use the high labeled rate when targeting stink bug nymphs. 

Restrictions: 

Foliar application of this product is prohibited from onset of flowering until flowering is complete unless the rate is limited to 0.054 lbs. a.i./A and applications are made at night or during early morning hours when bees are not present.

Pre- and post-bloom applications: No restriction needed.  The product can be applied at any proposed rate. 
Do not apply CYCLANILIPROLE 50SL or other Group 28 insecticide consecutively more than 2 times within a 30 day period.
Do not apply CYCLANILIPROLE 50SL or other Group 28 insecticide more than 3 times within a single generation of insect pest(s) on a crop.
Make no more than 5 applications/crop per year.
Minimal interval between treatment is 10 days.
Do Not apply more than 82 fl oz CYCLANILIPROLE 50SL per acre per year.
Pre-Harvest Interval (PHI)  -  7 days
*Includes all members of the Pome Crop Group Family including Apple; azarole; crabapple; loquat; mayhaw; medlar; pear; pear, Asian; quince; quince, Chinese; quince, Japanese; tejocote; cultivars, varieties, and/or hybrids of these.

                              DIRECTIONS FOR USE
Crop
Insects
Use Rate
                                Fl. Oz. Product
                                   Per Acre
Instructions
Tree Nuts (Crop Group 14-12)*
Codling moth
Navel orange worm
Peach twig borer
Walnut husk fly
Obliquebanded leafroller
Oriental fruit moth
Pecan nut casebearer
Hickory shuckworm
Stink bug spp.**

**Suppression Only. Use in conjunction with an effective control program.
16.4 to 22.0 fl oz
                                       
                         (0.054 to 0.072 lb. a.i. /A)
Application Instructions:  Thorough coverage is essential to achieve best results. Select a spray volume appropriate for the size of trees and density of foliage. For best results apply 100-200 gallons water per acre.  
Codling Moth Use the high rate of 22 fl oz to insure thorough coverage. Make first application just prior to or at the beginning of egg hatch. Applications typically provide 10-14 days of protection. Use pheromone trap catches and local degree day based spray timing advisories to determine the development of each codling moth generation. For effective resistance management make applications of CYCLANILIPROLE 50SL in one codling moth generation before rotating to an insecticide with a different mode of action (Non- Group 28) in the next generation. 
Navel Orange Worm Apply a spring spray for navel orangeworm just after the first eggs of the spring brood hatch. For applications at hullsplit apply once it has been determined that egg laying has begun. Higher rates and multiple applications may be needed depending upon level of infestation.
Obliquebanded Leafroller For overwintering larvae apply in at first sign of active feeding. 
Peach Twig Borer Use higher rate for heavy infestations and for application to overwintering generations. Applications to summer generations should be timed during peak egg laying periods. 
Stink bugs** CYCLANILIPROLE 50SL provides suppression of stink bug NYMPHS ONLY. Use as a part of an Integrated Pest Management (IPM) program and target the most susceptible life stages and application timings. Use in conjunction with other modes of action and effective control products. Performance is enhanced when used with an effective adjuvant. For best results, use the high labeled rate when targeting stink bug nymphs.
Restrictions:

[Option 1 - Foliar application of this product is prohibited from onset of flowering until flowering is complete unless the rate is limited to 0.054 lbs. a.i./A and applications are made at night or during early morning hours when bees are not present.

Pre- and post-bloom applications: No restriction needed.  The product can be applied at any proposed rate.]

[Option 2 - Foliar application of this product is prohibited from onset of flowering until flowering is complete.]

Do not apply CYCLANILIPROLE 50SL or other Group 28 insecticide consecutively more than 2 times within a 30 day period.
Do not apply CYCLANILIPROLE 50SL or other Group 28 insecticide more than 3 times within a single generation of insect pest(s) on a crop.
Make no more than 5 applications/crop per year.
Minimal interval between treatment is 10 days.
Do Not apply more than 82 fl oz CYCLANILIPROLE 50SL per acre per year.
Pre-Harvest Interval (PHI)  -  30 days
*Includes all members of the Tree Nut Crop Group Family including African nut-tree; Almond; Beechnut; Brazil nut; Brazilian pine; Bunya; Bur oak; Butternut; Cajou nut; Candlenut; Cashew; Chestnut; Chinquapin; Coconut; Coquito nut; Dika nut; Ginkgo; Guiana chestnut; Hazelnut; Heartnut; Hickory nut; Japanese horse-chestnut; Macadamia nut; Mongongo nut; Monkey-pot; Monkey puzzle nut; Okari nut; Pachira nut; Peach palm nut; Pecan; Pequi; Pili  nut; Pine nut; Pistachio; Sapucaia nut; Tropical almond; Walnut, black; Walnut, English; Yellowhorn; cultivars, varieties and/or hybrids of these.

                              DIRECTIONS FOR USE
                                     Crop
                                    Insects
Use Rate
                                Fl. Oz. Product
                                   Per Acre
                                 Instructions
Stone Fruit (Crop Group 12-12)*
Obliquebanded leafroller
Omnivorous leafroller
Oriental fruit moth
Peach twig borer
Codling moth
Tufted apple budmoth
Cherry fruit fly
Western cherry fruit fly
Spotted wing drosophila
Japanese beetle
Western flower thrips
Plum curculio
Stink bug spp.**

**Suppression Only. Use in conjunction with an effective control program.
16.4-22 fl oz.
                                       
                         (0.054 to 0.072 lb. a.i. /A)
                                       
Application Instructions:  Thorough coverage is essential to achieve best results.  Select a spray volume appropriate for the size of trees and density of foliage. For best results apply 100-200 gallons water per acre.  
Obliquebanded Leafroller Apply in the pink to petal fall stage at the first sign of active feeding. Can also be used later in the growing season at or just prior to egg hatch.
Peach Twig Borer Can be applied in both the dormant and growing season. Use higher rate for heavy infestations and for application to dormant generations. Applications to summer generations should be timed during peak egg laying periods. 
Thrips Apply in the pink to petal fall stage at the first sign of active feeding.
Cherry Fruit Fly and Spotted Wing Drosophila Apply at the 22 fl oz rate for best results. Use degree day models to determine application timing. Repeat applications at 7 day intervals depending on weather conditions. Thorough coverage is essential, and multiple applications may be required depending upon level of infestation.
Stink bugs** CYCLANILIPROLE 50SL provides suppression of stink bug NYMPHS ONLY. Use as a part of an Integrated Pest Management (IPM) program and target the most susceptible life stages and application timings. Use in conjunction with other modes of action and effective control products. Performance is enhanced when used with an effective adjuvant. For best results, use the high labeled rate when targeting stink bug nymphs.
Restrictions: 

Foliar application of this product is prohibited from onset of flowering until flowering is complete unless the application is made to prevent or control a threat to public and/or animal health as determined by at state, tribal, authorized local health department or vector control agency;    

Pre- and post-bloom applications: No restriction needed.  The product can be applied at any proposed rate. 
Do not apply CYCLANILIPROLE 50SL or other Group 28 insecticide consecutively more than 2 times within a 30 day period.
Do not apply CYCLANILIPROLE 50SL or other Group 28 insecticide more than 3 times within a single generation of insect pest(s) on a crop.
Make no more than 5 applications/crop per year.
Minimal interval between treatment is 7 days.
Do not apply more than 82 fl oz CYCLANILIPROLE 50SL per acre per year.
Pre-Harvest Interval (PHI)  -  7 days
*Includes all members of the Stone Fruit Crop Group Family including Apricot; apricot, Japanese; capulin; cherry, black; cherry, Nanking; cherry, sweet; cherry, tart; Jujube, Chinese; nectarine; peach; plum; plum, American; plum, beach; plum, Canada; plum, cherry; plum, Chickasaw; plum, Damson; plum, Japanese; plum, Klamath; plum, prune; plumcot; sloe; cultivars, varieties, and/or hybrids of these.

DIRECTIONS FOR USE
Crop
Insects
Use Rate
                                Fl. Oz. Product
Per Acre
Instructions

Leafy Vegetables (non-brassica) (Crop Group 4)*

Beet Armyworm
Cabbage looper
Corn earworm
Diamondback moth
Flea beetles
Fall armyworm
Western yellowstriped armywormLeafminers (Liriomyza species)
Western flower thrips
Whiteflies**
Stink bug spp.**
Cotton (melon) aphid

**Suppression only. Use in conjunction with an effective control program.

                              10.9 to 16.4 fl oz
                                       
                         (0.036 to 0.054 lb. a.i. /A) 

Application Instructions:  Thorough coverage is essential to achieve best results. Use 16.4 fl oz/A if Leafminers or thrips are present.

Diamondback Moth For resistance management, do not apply Cyclaniliprole 50SL to successive generations of diamondback moth, or more than twice within a single generation or 30 day period. Applications to the following generation of diamondback moth should be with an effective non-Group 28 insecticide (different mode of action in different IRAC group). Do not apply less than 10.9 fl. oz per acre for control of diamondback moth. Make no more than 6 applications of CYCLANILIPROLE 50SL at the 10.9 fl. oz. rate, and no more than 4 applications at the 16.4 fl. oz. rate within a calendar year at the same location for control of diamondback moth.
Flea beetles For best performance, use the high labeled rate of 16.4 fl oz/A. 
Stink bugs** CYCLANILIPROLE 50SL provides suppression of stink bug NYMPHS ONLY. Use as a part of an Integrated Pest Management (IPM) program and target the most susceptible life stages and application timings. Use in conjunction with other modes of action and effective control products. Performance is enhanced when used with an effective adjuvant. For best results, use the high labeled rate when targeting stink bug nymphs.
Aphids For best results use with an effective adjuvant. Use the higher labeled rate for best performance.

Restrictions: 

Do not apply to crops grown for seed.
Bloom restriction:  The product cannot be applied during the blooming period unless the rate is limited to 0.054 lbs. a.i./A and applications are made at night or during early morning hours when bees are not present.

Do not apply CYCLANILIPROLE 50SL or other Group 28 insecticide consecutively more than 2 times within a 30 day period.
Do not apply CYCLANILIPROLE 50SL or other Group 28 insecticide more than 3 times within a single generation of insect pest(s) on a crop.
Make no more than 6 applications/crop per year.
Minimal interval between treatment is 5 days.
Do not apply more than 65.6 fl oz CYCLANILIPROLE 50SL per acre per year.
Pre-Harvest Interval (PHI)  -  1 day
*Includes all members of the Leafy Vegetable Crop Group Family including Amaranth, leafy; arugula (roqette); cardoon; celery; celery (Chinese); celtuce; chervil; Chinese spinach; chrysanthemum (edible leaved); chrysanthemum (garland); corn salad cress (garden); dandelion; dock (sorrel); endive (escarole); Florence fennel; lettuce (head and leaf); orach; parsley; purslane (garden and winter); radicchio (red chicory); rhubarb; spinach; spinach, vine; spinach, New Zealand; Swiss chard

DIRECTIONS FOR USE
Crop
Insects
Use Rate
                                Fl. Oz. Product
Per Acre
Instructions

Brassica (Cole) Leafy Vegetables
(Crop Group5)*

Beet armyworm
Cabbage looper 
Corn earworm
Cross striped cabbage moth
Diamondback moth
Imported cabbageworm
Western yellowstriped armyworm
Flea beetles
Leafminers (Liriomyza species)
Western flower thrips
Whiteflies**
Stink bug spp.**
Cotton (melon) aphid

**Suppression only.  Use in conjunction with an effective control program.

                              10.9 to 16.4 fl oz
                                       
                         (0.036 to 0.054 lb. a.i. /A) 

Application Instructions: Thorough coverage is essential to achieve best results. Use 16.4 fl oz/A if Leafminers or thrips are present.    

Diamondback Moth For resistance management, do not apply Cyclaniliprole 50SL to successive generations of diamondback moth, or more than twice within a single generation or 30 day period.  Applications to the following generation of diamondback moth should be with an effective non-Group 28 insecticide (different mode of action in different IRAC group). Do not apply less than 10.9 fl. oz per acre for control of diamondback moth. Make no more than 6 applications of CYCLANILIPROLE 50SL at the 10.9 fl. oz. rate, and no more than 4 applications at the 16.4 fl. oz. rate within a calendar year at the same location for control of diamondback moth.
Flea beetles For best performance, use the high labeled rate of 16.4 fl oz/A. 
Stink bugs** CYCLANILIPROLE 50SL provides suppression of stink bug NYMPHS ONLY. Use as a part of an Integrated Pest Management (IPM) program and target the most susceptible life stages and application timings. Use in conjunction with other modes of action and effective control products. Performance is enhanced when used with an effective adjuvant. For best results, use the high labeled rate when targeting stink bug nymphs.
Aphids For best results use with an effective adjuvant. Use the higher labeled rate for best performance.

Restrictions: 
Do not apply to crops grown for seed.
Bloom restriction:  The product cannot be applied during the blooming period unless the rate is limited to 0.054 lbs. a.i./A and applications are made at night or during early morning hours when bees are not present.
Do not apply CYCLANILIPROLE 50SL or other Group 28 insecticide consecutively more than 2 times within a 30 day period.
Do not apply CYCLANILIPROLE 50SL or other Group 28 insecticide more than 3 times within a single generation of insect pest(s) on a crop.
Make no more than 6 applications/crop per year.
Minimal interval between treatment is 5 days.
Do not apply more than 65.6 fl oz CYCLANILIPROLE 50SL per acre per year.
Pre-Harvest Interval (PHI)  -  1 day
*Includes all members of the Brassica Vegetable Crop Group Family including Broccoli; broccoli Chinese (gai lon); broccoli raab (rapini); Brussels sprouts; cabbage; Chinese cabbage (bok choy); cabbage (napa); Chinese mustard (gai choy); cauliflower; cavalo broccoli; collards; kale; kohlrabi; mizuna; mustard greens; mustard spinach; rape greens.

DIRECTIONS FOR USE
Crop
Insects
Use Rate
                                Fl. Oz. Product
                                   Per Acre
Instructions

Fruiting Vegetables (Crop Group 8-10)*

Beet armyworm
Cabbage looper
Colorado potato beetle
Fall armyworm
Southern armyworm
Tomato fruitworm Tomato hornworm
Tomato pinworm
Tomato psyllid
Pepper weevil
European corn borer
Yellow striped armyworm
Leafminers (Liriomyza species)
Western flower thrips
Whiteflies**
Stink bug spp.**
Cotton (melon) aphid

**Suppression only.  Use in conjunction with an effective control program.

10.9 to 16.4 fl oz
                                       
                         (0.036 to 0.054 lb. a.i. /A) 

Application Instructions: Thorough coverage is essential to achieve best results. Use 16.4 fl oz/A if Leafminers or thrips are present.  

Pepper Weevil For best results, use the high labeled rate of 16.4 fl oz/A. 
Stink bugs** CYCLANILIPROLE 50SL provides suppression of stink bug NYMPHS ONLY. Use as a part of an Integrated Pest Management (IPM) program and target the most susceptible life stages and application timings. Use in conjunction with other modes of action and effective control products. Performance is enhanced when used with an effective adjuvant. For best results, use the high labeled rate when targeting stink bug nymphs.
Aphids For best results use with an effective adjuvant. Use the higher labeled rate for best performance.

Restrictions: 
Bloom restriction:  The product cannot be applied during the blooming period unless the rate is limited to 0.054 lbs. a.i./A and applications are made at night or during early morning hours when bees are not present.

Do not apply CYCLANILIPROLE 50SL or other Group 28 insecticide consecutively more than 2 times within a 30 day period.
Do not apply CYCLANILIPROLE 50SL or other Group 28 insecticide more than 3 times within a single generation of insect pest(s) on a crop.
Make no more than 4 applications/crop per year.
Minimal interval between treatment is 5 days.
Do not apply more than 65.6 fl oz CYCLANILIPROLE 50SL per acre per year.
Pre-Harvest Interval (PHI)  -  1 day
*Includes all members of the Fruiting Vegetable Crop Group Family including African eggplant; bush tomato; bell pepper; cocona; currant tomato; eggplant; garden huckleberry; goji berry; groundcherry; martynia; naranjilla; okra; pea eggplant; pepino; nonbell pepper; roselle; scarlet eggplant; sunberry; tomatillo; tomato; tree tomato; 
cultivars, varieties, and/or hybrids of these. 

                              DIRECTIONS FOR USE
Crop
Insects
Use Rate
                                Fl. Oz. Product
Per Acre
Instructions

Cucurbits Vegetables (Crop Group 9)*

Beet Armyworm
Cabbage looper
Melon worm
Pickleworm
Southern armyworm
Fall armyworm
Striped cucumber beetle
Leafminers (Liriomyza species)
Flea beetles
Western yellowstriped armyworm
Western flower thrips
Onion thrips
Whiteflies**
Stink bug spp.**
Squash bug**
Cotton (melon) aphid

**Suppression only.  Use in conjunction with an effective control program.

                              10.9 to 16.4 fl oz
                                       
                         (0.036 to 0.054 lb. a.i. /A) 

Application Instructions: Thorough coverage is essential to achieve best results.  Use 16.4 fl oz/A if Leafminers or thrips are present.  

Flea beetles For best performance, use the high labeled rate of 16.4 fl oz/A. 
Stink bugs and Squash bug** CYCLANILIPROLE 50SL provides suppression of stink bug and squash bug NYMPHS ONLY. Use as a part of an Integrated Pest Management (IPM) program and target the most susceptible life stages and application timings. Use in conjunction with other modes of action and effective control products. Performance is enhanced when used with an effective adjuvant. For best results, use the high labeled rate when targeting stink bug and squash bug nymphs.
Aphids For best results, use with an effective adjuvant. Use the high labeled rate for best performance.

Restrictions: 

Bloom restriction: The product cannot be applied during the blooming period unless the application is being made in the time period between 2 hours prior to sunset until sunrise; OR the application is being made at a time when the temperature at the application site is 50 degrees F or less.

Do not apply CYCLANILIPROLE 50SL or other Group 28 insecticide consecutively more than 2 times within a 30 day period.
Do not apply CYCLANILIPROLE 50SL or other Group 28 insecticide more than 3 times within a single generation of insect pest(s) on a crop.
Make no more than 4 applications/crop per year.
Minimal interval between treatment is 5 days.
Do not apply more than 65.6 fl oz CYCLANILIPROLE 50SL per acre per year.
Pre-Harvest Interval (PHI)  -  1 day
*Includes all members of the Cucurbit Vegetable Crop Group Family including Chayote (fruit); Chinese waxgourd (Chinese preserving melon); Citron melon; Cucumber; Gherkin; Gourd, edible (includes hyotan, cucuzza, hechima, Chinese okra); Momordica spp (includes balsam apple, balsam pear, bitter melon, Chinese cucumber); Muskmelon, hybrids and/or cultivars of Cucumis melo (includes true cantaloupe, cantaloupe, casaba, crenshaw melon, golden pershaw melon, honeydew melon, honey balls, mango melon, Persian melon, pineapple melon, Santa Claus melon, and snake melon); Pumpkin; Squash, summer (includes crookneck squash, scallop squash, straightneck squash, vegetable marrow, zucchini); Squash, winter (includes butternut squash, calabaza, hubbard squash, acorn squash, spaghetti squash; Watermelon (includes hybrids and/or varieties of Citrullus lanatus)
 

                              DIRECTIONS FOR USE
Crop
Insects
Use Rate
Fl. Oz. Product
Per Acre
Instructions
Small Fruit Vine Climbing Crop Subgroup including Grapes (Crop Subgroup 13-07F)*
Grape berry moth
Omnivorous leafroller
Western flower thrips 
Cutworms
Grape leaf folder
Orange tortrix
Obliquebanded leafroller
Redbanded leafroller
Grape leaf skeletonizer
European grapevine moth
Japanese beetle
Spotted wing drosophila
Stink bug spp.**

**Suppression only.  Use in conjunction with an effective control program.
                                16.4-22 fl oz.
                                       
                         (0.054 to 0.072 lb. a.i. /A)
                                       
                                       
Application Instructions:
For use on all types of grapes (wine, table, raisin, and juice).  Thorough coverage is essential to achieve best results.  Select a spray volume appropriate for the density of foliage.  For best results apply 100-150 gallons water per acre.  

Thrips Apply in the bloom or rapid shoot growth if populations exceed damage threshold. 
Spotted Wing Drosophila Apply at the 22 fl oz rate for best results. Use degree day models to determine application timing. Repeat applications at 7 day intervals depending on weather conditions. Thorough coverage is essential, and multiple applications may be required depending upon level of infestation.
Stink bugs** CYCLANILIPROLE 50SL provides suppression of stink bug NYMPHS ONLY. Use as a part of an Integrated Pest Management (IPM) program and target the most susceptible life stages and application timings. Use in conjunction with other modes of action and effective control products. Performance is enhanced when used with an effective adjuvant. For best results, use the high labeled rate when targeting stink bug nymphs.
Restrictions: 

Bloom restriction:  The product cannot be applied during the blooming period unless the rate is limited to 0.054 lbs. a.i./A and applications are made at night or during early morning hours when bees are not present.

Do not apply CYCLANILIPROLE 50SL or other Group 28 insecticide consecutively more than 2 times within a 30 day period.
Do not apply CYCLANILIPROLE 50SL or other Group 28 insecticide more than 3 times within a single generation of insect pest(s) on a crop.
Make no more than 3 applications/crop per year.
Minimal interval between treatment is 7 days.
Do Not apply more than 66.0 fl oz CYCLANILIPROLE 50SL per acre per year.
Pre-Harvest Interval (PHI)  -  7 days

Includes all members of the Small Fruit Vine Climbing Crop Subgroup 13-07F, except fuzzy kiwifruit:  Amur river grape; gooseberry; grape; kiwifruit, hardy; maypop; schisandra berry; cultivars, varieties, and/or hybrids of these.

WARRANTY AND LIMITATION OF DAMAGES

Seller warrants to those persons lawfully acquiring title to this product that at the time of first sale of this product by Seller that this product conformed to its chemical description and was reasonably fit for the purposes stated on the label when used in accordance with Seller's directions under normal conditions of use.  To the extent consistent with applicable law, Buyers and users of this product assume the risk of any use contrary to such directions.  EXCEPT AS PROVIDED ELSEWHERE IN WRITING CONTAINING AN EXPRESS REFERENCE TO THIS WARRANTY AND LIMITATION OF DAMAGES, SELLER MAKES NO OTHER EXPRESS OR IMPLIED WARRANTY OR GUARANTY, INCLUDING ANY OTHER EXPRESS OR IMPLIED WARRANTY OF FITNESS OR
OF MERCHANTABILITY, AND NO AGENT OF SELLER IS AUTHORIZED TO DO SO.  In no event shall Seller's liability for any breach of warranty or guaranty exceed the purchase price of the product as to which a claim is made. To the extent consistent with applicable law, Buyers and users of this product are responsible for all loss or damage from use or handling of this product which results from conditions beyond the control of Seller, including, but not limited to, incompatibility with other products unless otherwise expressly provided in Directions for Use of this product, weather conditions, cultural practices, moisture conditions or other environmental conditions outside of the ranges that are generally recognized as being conducive to good agricultural and/or horticultural practices.