Document ID: EPA-HQ-OPP-2008-0125-0010
Agency: epa
Document Type: Supporting & Related Material
Title: 
Posted Date: 2011-02-02T05:00Z

UNITED STATES ENVIRONMENTAL PROTECTION AGENCY

WASHINGTON, D.C.  20460

OFFICE OF

CHEMICAL SAFETY AND

POLLUTION PREVENTION

  SEQ CHAPTER \h \r 1 Date:		22-DEC-2010

Subject:	Sulfentrazone – REVISED Acute and Chronic Aggregate Dietary
(Food and Drinking Water) Exposure and Risk Assessments for the Section
3 Registration Request to Add New Uses on:  Brassica, Head and Stem,
Subgroup 5A; Brassica, Leafy Greens, Subgroup 5B; Melon Subgroup 9A;
Fruiting Vegetable, Group 8 and Okra; Pea, Succulent; Flax; Strawberry;
Tuberous and Corm Vegetable, Subgroup 1C; and Miscellaneous Fruiting
Vegetables.  

PC Code:  129081	DP Barcode:  D384090  

Decision No.:  388050	Registration Nos:  279-3220 & 279-3189

Petition No.:  7E7308	Regulatory Action:  Amended Section 3

Risk Assessment Type:  Dietary	Case No.:  7231

TXR No.:  NA	CAS No.:  122836-35-5

MRID No.:  NA	40 CFR:  §180.498

From:		Julie L. Van Alstine, MPH, Environmental Health Scientist

		Risk Assessment Branch 1 (RAB1)

		Health Effects Division (HED, 7509P)

Through:	Nancy Dodd, Chemist

		Mohsen Sahafeyan, Chemist

		Dietary Exposure Science Advisory Council (DESAC)

	

	and

	George F. Kramer, Ph.D., Branch Senior Chemist

		RAB1/HED (7509P)

To:		Barbara Madden RM05

		Registration Division (RD; 7505P)

		

		and

		Kelly Lowe, Risk Assessor

		RAB1/HED (7509P)

NOTE:  This document supersedes Memo, W. Wassell, 03-APR-2009 (D362644)
and Memo, J. Van Alstine, 18-AUG-2010 (D364912).  This assessment has
been updated to include revisions to the acute reference dose for
females 13-49 years old.  

Executive Summary

Acute and chronic aggregate dietary (food and drinking water) exposure
and risk assessments were conducted using the Dietary Exposure
Evaluation Model - Food Consumption Intake Database (DEEM-FCID(, ver.
2.03).  DEEM-FCID( incorporates food consumption data from the United
States Department of Agriculture (USDA) Continuing Surveys of Food
Intakes by Individuals (CSFII; 1994-1996 and 1998).  The revised
assessment is being conducted in support of new uses on Brassica, head
and stem, subgroup 5A; Brassica, leafy greens, subgroup 5B; melon
subgroup 9A; fruiting vegetable, group 8 and okra; pea, succulent; flax;
strawberry; tuberous and corm vegetable, subgroup 1C; and miscellaneous
fruiting vegetables; and changes to the toxicological doses and
endpoints for sulfentrazone.  

 

Acute Dietary (Food and Drinking Water) Exposure Results and
Characterization

 

The acute analysis assumed tolerance-level residues for all commodities,
100% crop treated (%CT), and DEEM( (ver. 7.81) default processing
factors (as necessary).  The acute analysis also incorporated the
drinking water estimates provided by the Environmental Fate and Effects
Division (EFED).  The resulting acute food plus water risk estimates are
below HED’s level of concern [<100% of the acute population-adjusted
dose (aPAD)] at the 95th percentile of the exposure distribution for the
U.S. general population (less than 1% aPAD), and all population
subgroups.  The aPAD is lower for females 13 to 49 years old.  The
population subgroup with the greatest risk was  SEQ CHAPTER \h \r 1 
females 13 to 49 years old which utilized less than 3% of the aPAD.  

Chronic Dietary (Food and Drinking Water) Exposure Results and
Characterization 

The chronic analysis assumed tolerance-level residues, 100% CT, and
DEEM( (ver. 7.81) default processing factors (as necessary) for all
commodities.  The chronic analysis also incorporated the drinking water
estimates provided by EFED.  The resulting chronic risk estimates are
below HED’s level of concern.  The most highly exposed population
subgroup was children 1-2 years old, which utilized less than 4% of the
chronic PAD (cPAD).

Cancer Dietary (Food and Drinking Water) Exposure Results and
Characterization

A cancer dietary assessment was not conducted because sulfentrazone is
classified as “not likely to be carcinogenic to humans.”

I.  Introduction

Dietary risk assessment incorporates both exposure and toxicity of a
given pesticide.  For acute and chronic assessments, the risk is
expressed as a percentage of a maximum acceptable dose (i.e., the dose
which HED has concluded will result in no unreasonable adverse health
effects).  This dose is referred to as the PAD.  The PAD is equivalent
to a point-of-departure [POD; e.g., no-observable-adverse-effect-level
(NOAEL)] divided by the required uncertainty or safety factors.  For
acute and non-cancer chronic exposures, HED is concerned when estimated
dietary risk exceeds 100% of the PAD.  References which discuss the
acute and chronic risk assessments in more detail are available on the
EPA/pesticides web site:  “Available Information on Assessing Exposure
from Pesticides, A User’s Guide,” 6/21/2000, web link:    HYPERLINK
"http://www.epa.gov/fedrgstr/EPA-PEST/2000/July/Day-12/6061.pdf" 
http://www.epa.gov/fedrgstr/EPA-PEST/2000/July/Day-12/6061.pdf ; or see
SOP 99.6 (8/20/99).  

The most recent sulfentrazone dietary exposure assessment was conducted
by J. Van Alstine (18-AUG-2010; D364912).

II.  Residue Information

Residues of Concern in Plants and Livestock:  The HED Metabolism
Assessment Review Committee (MARC) has determined that the parent
compound, sulfentrazone, and the metabolite HMS
[N-(2,4-dichloro-5-(4-(difluoromethyl)-4,5-dihydro-3-hydroxymethyl-5-oxo
-1H-1,2,4-triazol-yl)phenyl)methanesulfonamide)] are the residues of
concern in soybeans, and that sulfentrazone and its metabolites HMS and
DMS [(N-2,4-
dichloro-5-[4-(difluoromethyl)-4,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl)p
henyl)methanesulfonamide] are the residues of concern in rotational
crops (Memo, G. Kramer, 14-JUN-1996; D226434).  HED has concluded that
the results of the rotational crop metabolism studies may be translated
to support preemergent uses on all types of crops.  Additionally,
sulfentrazone and its metabolites HMS and DMS were identified as the
residues of concern in meat, milk, poultry, and eggs.  The HED MARC
recommended that parent and 3-carboxylic acid sulfentrazone are the
residues of concern for the drinking-water assessment (Memo, G. Kramer
et al., 10-APR-2003; D288713).  HED continues to consider the given
metabolites and degradates to be the residues of concern for risk
assessment.  

Established/Recommended Tolerances:   SEQ CHAPTER \h \r 1  A tolerance
is currently established under 40 CFR §180.498(a)(1) for the combined
residues of sulfentrazone and its major metabolite, HMS, in/on soybean
seed at 0.05 ppm.  In addition, permanent tolerances are established
under 40 CFR §180.498(a)(2) for the combined residues of sulfentrazone
and its metabolites HMS and DMS in/on several food commodities; these
established tolerances range from 0.15 ppm (various plant commodities)
to 0.40 ppm (peanut meal).  Time-limited tolerances for the combined
residues of sulfentrazone and its metabolites HMS and DMS have been
established under 40 CFR §180.498(b) in connection with Section 18
Emergency Exemptions; these include tolerances for residues in/on bean,
succulent-seed without pod (lima bean and cowpea) at 0.1 ppm with a
12/31/07 expiration date, flax seed at 0.20 ppm with a 12/31/10
expiration date, and strawberry at 0.60 ppm with a 12/31/10 expiration
date.  Finally, tolerances are established under 40 CFR §180.498(d) for
inadvertent and indirect combined residues of sulfentrazone and its
metabolites HMS and DMS in/on cereal grain (excluding sweet corn) bran,
forage, grain, hay, hulls, stover, and straw at 0.1-0.6 ppm as a result
of the application of sulfentrazone to growing crops.

The proposed uses and the submitted data support the establishment of
the following tolerances for the combined residues of sulfentrazone and
its metabolites HMS and DMS in/on:

Brassica, head and stem, subgroup 5A	0.20 ppm

Brassica, leafy greens, subgroup 5B	0.40 ppm

Melon subgroup 9A	0.15 ppm

Vegetable, fruiting, group 8	0.15 ppm

Okra	0.15 ppm

Pea, succulent	0.15 ppm

Flax	0.15 ppm

Strawberry	0.15 ppm

Vegetable, tuberous and corm, subgroup 1C	0.15 ppm

Cocona	0.15 ppm

Eggplant, African	0.15 ppm

Eggplant, pea	0.15 ppm

Eggplant, scarlet	0.15 ppm

Goji berry	0.15 ppm

Huckleberry, garden	0.15 ppm

Martynia	0.15 ppm

Naranjilla	0.15 ppm

Roselle	0.15 ppm

Sunberry	0.15 ppm

Tomato, bush	0.15 ppm

Tomato, currant	0.15 ppm

Tomato, tree	0.15 ppm

Residues used in the Acute and Chronic Analyses:  These analyses
employed tolerance-level residues for all commodities, 100% CT, and
DEEM( (ver. 7.81) default processing factors.  The following fruiting
vegetables are not listed in DEEM-FCID( and were therefore not included
in the chronic assessment:  cocona, African eggplant, pea eggplant,
scarlet eggplant, goji berry, garden huckleberry, martynia, naranjilla,
roselle, sunberry, bush tomato, and currant tomato.  However, tree
tomato is included in DEEM( and was therefore included in the acute and
chronic assessments.

III.  Estimated Drinking Water Concentrations

Drinking water residues were incorporated directly into the acute and
chronic dietary analyses (“water, direct, all sources” and “water,
indirect, all sources”) and were provided by EFED   SEQ CHAPTER \h \r
1 (Memo, 9/15/2009, L. Liu, D366552).  The estimated drinking water
concentrations (EDWCs) were Tier 1 estimates for ground water using the
SCI-GROW Model (Screening Concentration In Ground Water) and surface
water using the FIRST Model [Food Quality Protection Act (FQPA) Index
Reservoir Screening Tool] for sulfentrazone and its major degradate,
3-carboxylic acid sulfentrazone.  The EDWCs were based on the use of
sulfentrazone on sugarcane, cabbage, potatoes, mint, or horseradish. 

For surface water, the acute (peak) sulfentrazone value is 32.0 ppb and
the annual average value ranges from 0.5 ppb in alkaline or neutral
waters (most common) to 5.1 ppb in acidic waters.  The groundwater
screening sulfentrazone concentration is 15.7 ppb.  For 3-carboxylic
acid sulfentrazone, the acute peak is 3.8 ppb and the annual average is
2.7 ppb. For 3-carboxylic acid sulfentrazone in groundwater, the
concentration is 10.3 ppb.  These values generally represent upper-bound
conservative estimates of the total residue concentrations that might be
found in surface water and groundwater due to the use of sulfentrazone
on sugarcane, cabbage, potatoes, mint, or horseradish.  These crops were
chosen for this assessment because the label permits use of the maximum
application rate (0.375 lb ai/A) and aerial application.  Aerial
application has the potential for most spray drift and is not compatible
with incorporation which would reduce surface water concentration
values.  EDWCs of 0.0358 ppm and 0.026 ppm were used in the acute and
chronic analyses, respectively.

  SEQ CHAPTER \h \r 1 

Table 1.  Estimated Tier 1 Concentrations of Sulfentrazone and
3-Carboxylic Acid Sulfentrazone in Drinking Water Due to the Use of
Sulfentrazone on Sugarcane, Cabbage, Potatoes, Mint, or Horseradish1. 
SEQ CHAPTER \h \r 1 

Chemical	Surface Water (ug/L)	Groundwater (ug/L)

	Acute	Chronic	Acute and Chronic

Sulfentrazone	32.0	5.1	15.7

3-Carboxylic Acid Sulfentrazone	3.8	2.7	10.3

Total	35.8	7.8	26.0

1 These crops were chosen for this assessment because the label permits
use of the maximum application rate (0.375 pounds active ingredient per
acre) and aerial application.

IV.  DEEM-FCID( Program and Consumption Information

Sulfentrazone acute and chronic dietary exposure and risk assessments
were conducted using DEEM-FCID( (Ver. 2.03), which incorporates
consumption data from USDA’s CSFII, (1994-1996 and 1998 data).  The
1994-1996, 1998 data are based on the reported consumption of more than
20,000 individuals over two non-consecutive survey days.  Foods “as
consumed” (e.g., apple pie) are linked to EPA-defined food commodities
(e.g., apples, peeled fruit - cooked; fresh or N/S; baked; or wheat
flour - cooked; fresh or N/S, baked) using publicly available recipe
translation files developed jointly by USDA/ARS and EPA.  For chronic
exposure assessment, consumption data are averaged for the entire U.S.
population and within population subgroups, but for acute exposure
assessment are retained as individual consumption events.  Based on
analysis of the 1994-96, 98 CSFII consumption data, which took into
account dietary patterns and survey respondents, HED concluded that it
is most appropriate to report risk for the following population
subgroups: the general U.S. population, all infants (<1 year old),
children 1-2 years old, children 3-5 years old, children 6-12 years old,
youth 13-19 years old, adults 20-49 years old, females 13-49 years old,
and adults 50+ years old.

For chronic dietary exposure assessment, an estimate of the residue
level in each food or food-form (e.g., orange or orange juice) on the
food commodity residue list is multiplied by the average daily
consumption estimate for that food/food form to produce a residue intake
estimate.  The resulting residue intake estimate for each food/food form
is summed with the residue intake estimates for all other food/food
forms on the commodity residue list to arrive at the total average
estimated exposure.  Exposure is expressed in mg/kg body weight/day and
as a percent of the cPAD.  This procedure is performed for each
population subgroup.

For acute exposure assessments, individual one-day food consumption data
are used on an individual-by-individual basis.  The reported consumption
amounts of each food item can be multiplied by a residue point estimate
and summed to obtain a total daily pesticide exposure for a
deterministic exposure assessment, or “matched” in multiple random
pairings with residue values and then summed in a probabilistic
assessment.  The resulting distribution of exposures is expressed as a
percentage of the aPAD on both a user (i.e., only those who reported
eating relevant commodities/food forms) and a per-capita (i.e., those
who reported eating the relevant commodities as well as those who did
not) basis.  In accordance with HED policy, per capita exposure and risk
are reported for all tiers of analysis.  However, for Tiers 1 and 2, any
significant differences in user vs. per capita exposure and risk are
specifically identified and noted in the risk assessment.

V.  Toxicological Information

The RAB1 toxicologists have reevaluated the sulfentrazone database and
updated the endpoints as necessary.  The toxicological endpoints
selected for sulfentrazone are summarized below in Table 2.



Table 2.  Summary of Toxicological Doses and Endpoints for Sulfentrazone
for Use in Human-Health Risk Assessments.

Exposure

Scenario	

Point of Departure	

Uncertainty/

FQPA Safety Factors	

RfD, PAD, Level of Concern for Risk Assessment	

Study and Relevant Toxicological Effects

Acute Dietary

(Females 13-49)	NOAEL = 14 mg/kg/day	UFA = 10X

UFH = 10X

FQPA SF = 1X	aRfD = aPAD = 0.14 mg/kg/day

	2-Gen Reproductive Toxicity Study - Rat

Offspring Toxicity LOAEL= 33 (M) and 40 (F) mg/kg/day based on reduced
prenatal viability (fetal & litter), reduced litter size, increased no.
of stillborn pups, reduced pup and litter postnatal survival and
decreased pup body weights throughout lactation.

Acute Dietary

(General population

including infants

and children)	NOAEL = 250 mg/kg/day

	UFA = 10X

UFH = 10X

FQPA SF = 1X	aRfD =aPAD = 2.5 mg/kg/day	Acute-Neurotoxicity Study - Rat

LOAEL = 750 mg/kg/day based on increased incidence of clinical signs and
FOB parameters and decreased motor activity.

Chronic Dietary

(all populations)	NOAEL= 10 mg/kg/day 	UFA = 10X

UFH = 10X

FQPA SF = 1X	cRfD = cPAD =

0.10 mg/kg/day

	Prenatal Developmental Toxicity - Rat

Developmental LOAEL = 25 mg/kg/day, based upon decreased mean fetal
weights, and retardation in skeletal development evidenced by an
increased number of litters with any variation and by decreased number
of caudal vertebral and metacarpal ossification sites.

Cancer (oral, dermal, inhalation)	

Classification: sulfentrazone is classified as “not likely to be
carcinogenic to humans.”

NOAEL = no-observed adverse-effect level.  LOAEL = lowest-observed
adverse-effect level.  UF = uncertainty factor.  UFA = extrapolation
from animal to human (interspecies).  UFH = potential variation in
sensitivity among members of the human population (intraspecies).  UFL =
extrapolation for use of a LOAEL in the absence of a NOAEL.  FQPA SF =
FQPA Safety Factor.  PAD = population-adjusted dose (a = acute, c =
chronic).  RfD = reference dose.  MOE = margin of exposure, LOC = level
of concern.

VI.  Results/Discussion

Acute and chronic analyses were performed using DEEM-FCID( (ver. 2.03). 
DEEM-FCID( estimates the dietary exposure and risk of the U.S.
population and various population subgroups.  The results reported are
for the general U.S. Population, all infants (<1 year old), children 1-2
years old, children 3-5 years old, children 6-12 years old, youth 13-19
years old, females 13-49 years old, adults 20-49 years old, and adults
50+ years old.  

The resulting acute food plus water risk estimates are below HED’s
level of concern (<100% aPAD) at the 95th percentile of the exposure
distribution for the general U.S. population (less than 1% aPAD), and
all population subgroups; the population subgroup with the greatest risk
was females 13 to 49 years, which utilized less than 3% of the aPAD. 
See Table 3 below for a summary of the results of the acute assessment. 
The resulting chronic risk estimates are also below HED’s level of
concern.  The most highly exposed population was children 1-2 years old
which utilized less than 4% of the cPAD.  See Table 4 below for a
summary of the results of the chronic assessment. 

Table 3.  Summary of Acute Dietary Exposure and Risk for Sulfentrazone
at the 95th Percentile.1

Population Subgroup	aPAD (mg/kg/day)	Exposure (mg/kg/day)	%aPAD

General U.S. Population	2.5	0.004347     	<1.0 

All Infants (< 1 year old)

0.009388     	<1.0

Children 1-2 years old

0.008187     	<1.0

Children 3-5 years old

0.007476     	<1.0

Children 6-12 years old

0.005284     	<1.0

Youth 13-19 years old

0.003695     	<1.0

Adults 20-49 years old

0.003341     	<1.0

Adults 50+ years old

0.002942     	<1.0

Females 13-49 years old	0.14	0.003256	2.3

1 The population with the greatest risk is bolded.

Table 4.  Summary of Chronic Dietary Exposure and Risk for
Sulfentrazone.1

Population Subgroup	cPAD (mg/kg/day)	Exposure (mg/kg/day)	%cPAD

General U.S. Population	0.10	0.001751                 	1.8

All Infants (< 1 year old)

0.003117                 	3.1

Children 1-2 years old

0.003565                 	3.6

Children 3-5 years old

0.003463                 	3.5

Children 6-12 years old

0.002404                 	2.4

Youth 13-19 years old

0.001660                 	1.7

Adults 20-49 years old

0.001492                 	1.5

Adults 50+ years old

0.001360                 	1.4

Females 13-49 years old

0.001451                 	1.5

1 The population with the greatest risk is bolded.

VII.  Characterization of Inputs/Outputs

The unrefined acute and chronic analyses assumed tolerance-level
residues for all commodities, 100% CT, and DEEM( (ver. 7.81) default
processing factors (as necessary).  These analyses are considered
conservative and could be refined through the use of anticipated-residue
estimates (ARs) for all commodities, %CT data for registered
commodities, and empirical processing factors.

VIII.  Conclusions

The acute and chronic dietary exposure and risk estimates for
sulfentrazone are below HED’s level of concern.  For food and drinking
water acute exposure, the population subgroup with the greatest risk was
females 13 to 49 years old, which utilized less than 3% of the aPAD. 
SEQ CHAPTER \h \r 1   

For food and drinking water chronic exposure, the most highly-exposed
population subgroup was children 1-2 years old, which utilized less than
4% of the cPAD.  The acute and chronic dietary exposure assessments
support the new uses proposed for sulfentrazone.

Attachments

Attachment 1:  DEEM-FCID( Acute Residue File.

Attachment 2:  DEEM-FCID( Acute Exposure Estimates for the General
Population Including Infants and Children. 

Attachment 3:  DEEM-FCID( Chronic Residue File.

Attachment 4:  DEEM-FCID( Chronic Exposure Estimates.

RDI:  DE SAC Reviewers:  19-NOV-2010; G. Kramer 17-NOV-2010

DP No.:  D384090

Petition No.:  7E7308   

PC Code:  129081

J. L. Van Alstine:S-10951:Potomac Yard:703-603-8866:7509P:RAB1

Attachment 1:  DEEM-FCID( Acute Residue File.

Filename: C:\Documents and Settings\jlangsda\My
Documents\Chemicals\Sulfentrazone\November 2010\Sent to
Reviewers\129081-acute-2009-jml__01 DEC 2010.R98

Chemical: Sulfentrazone

RfD(Chronic): .1 mg/kg bw/day  NOEL(Chronic): 0 mg/kg bw/day

RfD(Acute): 2.5 mg/kg bw/day  NOEL(Acute):  0 mg/kg bw/day

Date created/last modified: 12-01-2010/09:50:36/8          Program ver.
2.03

------------------------------------------------------------------------
--------

  EPA    Crop                                   Def Res     Adj.Factors 
 Comment

  Code    Grp  Commodity Name                    (ppm)       #1    #2   

-------- ---- -------------------------------  ----------  ------ ------
 -------

01011900 1AB  Horseradish                        0.200000   1.000  1.000
 1E0631

          Full comment: 1E06311; TLT 0.10 ppm, exp. 12/31/05

01030150 1CD  Arrowroot, flour                   0.150000   1.000  1.000
 

01030151 1CD  Arrowroot, flour-babyfood          0.150000   1.000  1.000
 

01030170 1CD  Artichoke, Jerusalem               0.150000   1.000  1.000
 

01030820 1CD  Cassava                            0.150000   1.000  1.000
 

01030821 1CD  Cassava-babyfood                   0.150000   1.000  1.000
 

01031390 1CD  Dasheen, corm                      0.150000   1.000  1.000
 

01031660 1CD  Ginger                             0.150000   1.000  1.000
 

01031661 1CD  Ginger-babyfood                    0.150000   1.000  1.000
 

01031670 1CD  Ginger, dried                      0.150000   1.000  1.000
 

01032960 1C   Potato, chips                      0.150000   1.000  1.000
 

01032970 1C   Potato, dry (granules/ flakes)     0.150000   6.500  1.000
 

01032971 1C   Potato, dry (granules/ flakes)-b   0.150000   6.500  1.000
 

01032980 1C   Potato, flour                      0.150000   6.500  1.000
 

01032981 1C   Potato, flour-babyfood             0.150000   6.500  1.000
 

01032990 1C   Potato, tuber, w/peel              0.150000   1.000  1.000
 

01032991 1C   Potato, tuber, w/peel-babyfood     0.150000   1.000  1.000
 

01033000 1C   Potato, tuber, w/o peel            0.150000   1.000  1.000
 

01033001 1C   Potato, tuber, w/o peel-babyfood   0.150000   1.000  1.000
 

01033660 1CD  Sweet potato                       0.150000   1.000  1.000
 

01033661 1CD  Sweet potato-babyfood              0.150000   1.000  1.000
 

01033710 1CD  Tanier, corm                       0.150000   1.000  1.000
 

01033870 1CD  Turmeric                           0.150000   1.000  1.000
 

01034060 1CD  Yam, true                          0.150000   1.000  1.000
 

01034070 1CD  Yam bean                           0.150000   1.000  1.000
 

05010610 5A   Broccoli                           0.200000   1.000  1.000
 

05010611 5A   Broccoli-babyfood                  0.200000   1.000  1.000
 

05010620 5A   Broccoli, Chinese                  0.200000   1.000  1.000
 

05010640 5A   Brussels sprouts                   0.200000   1.000  1.000
 

05010690 5A   Cabbage                            0.200000   1.000  1.000
 1E0631

          Full comment: 1E06311

05010710 5A   Cabbage, Chinese, napa             0.200000   1.000  1.000
 1E0631

          Full comment: 1E06311

05010720 5A   Cabbage, Chinese, mustard          0.200000   1.000  1.000
 1E0631

          Full comment: 1E06311

05010830 5A   Cauliflower                        0.200000   1.000  1.000
 

05011960 5A   Kohlrabi                           0.200000   1.000  1.000
 

05020630 5B   Broccoli raab                      0.400000   1.000  1.000
 

05020700 5B   Cabbage, Chinese, bok choy         0.400000   1.000  1.000
 1E0631

          Full comment: 1E06311

05021170 5B   Collards                           0.400000   1.000  1.000
 

05021940 5B   Kale                               0.400000   1.000  1.000
 

05022290 5B   Mustard greens                     0.400000   1.000  1.000
 

05023180 5B   Rape greens                        0.400000   1.000  1.000
 

05023890 5B   Turnip, greens                     0.400000   1.000  1.000
 

06003470 6    Soybean, seed                      0.050000   1.000  1.000
 

06003480 6    Soybean, flour                     0.050000   1.000  1.000
 

06003481 6    Soybean, flour-babyfood            0.050000   1.000  1.000
 

06003490 6    Soybean, soy milk                  0.050000   1.000  1.000
 

06003491 6    Soybean, soy milk-babyfood or in   0.050000   1.000  1.000
 

06003500 6    Soybean, oil                       0.050000   1.000  1.000
 

06003501 6    Soybean, oil-babyfood              0.050000   1.000  1.000
 

06010430 6A   Bean, snap, succulent              0.150000   1.000  1.000
 

06010431 6A   Bean, snap, succulent-babyfood     0.150000   1.000  1.000
 

06012570 6A   Pea, edible podded, succulent      0.150000   1.000  1.000
 

06020310 6B   Bean, broad, succulent             0.150000   1.000  1.000
 

06020330 6B   Bean, cowpea, succulent            0.100000   1.000  1.000
 TLT, e

          Full comment: TLT, exp. 12/31/04

06020370 6B   Bean, lima, succulent              0.150000   1.000  1.000
 

06022550 6B   Pea, succulent                     0.150000   1.000  1.000
 

06022551 6B   Pea, succulent-babyfood            0.150000   1.000  1.000
 

06022590 6B   Pea, pigeon, succulent             0.150000   1.000  1.000
 

06030300 6C   Bean, black, seed                  0.150000   1.000  1.000
 2F0639

          Full comment: 2F06391

06030320 6C   Bean, broad, seed                  0.150000   1.000  1.000
 2F0639

          Full comment: 2F06391

06030340 6C   Bean, cowpea, seed                 0.150000   1.000  1.000
 2F0639

          Full comment: 2F06391

06030350 6C   Bean,  great northern, seed        0.150000   1.000  1.000
 2F0639

          Full comment: 2F06391

06030360 6C   Bean, kidney, seed                 0.150000   1.000  1.000
 2F0639

          Full comment: 2F06391

06030380 6C   Bean, lima, seed                   0.150000   1.000  1.000
 2F0639

          Full comment: 2F06391

06030390 6C   Bean, mung, seed                   0.150000   1.000  1.000
 2F0639

          Full comment: 2F06391

06030400 6C   Bean, navy, seed                   0.150000   1.000  1.000
 2F0639

          Full comment: 2F06391

06030410 6C   Bean, pink, seed                   0.150000   1.000  1.000
 2F0639

          Full comment: 2F06391

06030420 6C   Bean, pinto, seed                  0.150000   1.000  1.000
 2F0639

          Full comment: 2F06391

06030980 6C   Chickpea, seed                     0.150000   1.000  1.000
 2F0639

          Full comment: 2F06391

06030981 6C   Chickpea, seed-babyfood            0.150000   1.000  1.000
 2F0639

          Full comment: 2F06391

06030990 6C   Chickpea, flour                    0.150000   1.000  1.000
 2F0639

          Full comment: 2F06391

06031820 6C   Guar, seed                         0.150000   1.000  1.000
 2F0639

          Full comment: 2F06391

06031821 6C   Guar, seed-babyfood                0.150000   1.000  1.000
 2F0639

          Full comment: 2F06391

06032030 6C   Lentil, seed                       0.150000   1.000  1.000
 2F0639

          Full comment: 2F06391

06032560 6C   Pea, dry                           0.150000   1.000  1.000
 2F0639

          Full comment: 2F06391

06032561 6C   Pea, dry-babyfood                  0.150000   1.000  1.000
 2F0639

          Full comment: 2F06391

06032580 6C   Pea, pigeon, seed                  0.150000   1.000  1.000
 2F0639

          Full comment: 2F06391

08001480 8    Eggplant                           0.150000   1.000  1.000
 

08002340 8    Okra                               0.150000   1.000  1.000
 

08002700 8    Pepper, bell                       0.150000   1.000  1.000
 

08002701 8    Pepper, bell-babyfood              0.150000   1.000  1.000
 

08002710 8    Pepper, bell, dried                0.150000   1.000  1.000
 

08002711 8    Pepper, bell, dried-babyfood       0.150000   1.000  1.000
 

08002720 8    Pepper, nonbell                    0.150000   1.000  1.000
 New, S

          Full comment: New, Section 18

08002721 8    Pepper, nonbell-babyfood           0.150000   1.000  1.000
 New, S

          Full comment: New, Section 18

08002730 8    Pepper, nonbell, dried             0.150000   1.000  1.000
 New, S

          Full comment: New, Section 18

08003740 8    Tomatillo                          0.150000   1.000  1.000
 

08003750 8    Tomato                             0.150000   1.000  1.000
 

08003751 8    Tomato-babyfood                    0.150000   1.000  1.000
 

08003760 8    Tomato, paste                      0.150000   5.400  1.000
 

08003761 8    Tomato, paste-babyfood             0.150000   5.400  1.000
 

08003770 8    Tomato, puree                      0.150000   3.300  1.000
 

08003771 8    Tomato, puree-babyfood             0.150000   3.300  1.000
 

08003780 8    Tomato, dried                      0.150000  14.300  1.000
 

08003781 8    Tomato, dried-babyfood             0.150000  14.300  1.000
 

08003790 8    Tomato, juice                      0.150000   1.500  1.000
 

09010750 9A   Cantaloupe                         0.150000   1.000  1.000
 

09010800 9A   Casaba                             0.150000   1.000  1.000
 

09011870 9A   Honeydew melon                     0.150000   1.000  1.000
 

09013990 9A   Watermelon                         0.150000   1.000  1.000
 

09014000 9A   Watermelon, juice                  0.150000   1.000  1.000
 

15000250 15   Barley, pearled barley             0.100000   1.000  1.000
 Inadve

          Full comment: Inadvertent tol.

15000251 15   Barley, pearled barley-babyfood    0.100000   1.000  1.000
 Inadve

          Full comment: Inadvertent tol.

15000260 15   Barley, flour                      0.100000   1.000  1.000
 Inadve

          Full comment: Inadvertent tol.

15000261 15   Barley, flour-babyfood             0.100000   1.000  1.000
 Inadve

          Full comment: Inadvertent tol.

15000270 15   Barley, bran                       0.150000   1.000  1.000
 Inadve

          Full comment: Inadvertent tol.

15000650 15   Buckwheat                          0.100000   1.000  1.000
 Inadve

          Full comment: Inadvertent tol.

15000660 15   Buckwheat, flour                   0.100000   1.000  1.000
 Inadve

          Full comment: Inadvertent tol.

15001200 15   Corn, field, flour                 0.150000   1.000  1.000
 2F0639

          Full comment: 2F06391

15001201 15   Corn, field, flour-babyfood        0.150000   1.000  1.000
 2F0639

          Full comment: 2F06391

15001210 15   Corn, field, meal                  0.150000   1.000  1.000
 2F0639

          Full comment: 2F06391

15001211 15   Corn, field, meal-babyfood         0.150000   1.000  1.000
 2F0639

          Full comment: 2F06391

15001220 15   Corn, field, bran                  0.150000   1.000  1.000
 Inadve

          Full comment: Inadvertent tol.

15001230 15   Corn, field, starch                0.150000   1.000  1.000
 2F0639

          Full comment: 2F06391

15001231 15   Corn, field, starch-babyfood       0.150000   1.000  1.000
 2F0639

          Full comment: 2F06391

15001240 15   Corn, field, syrup                 0.150000   1.500  1.000
 2F0639

          Full comment: 2F06391

15001241 15   Corn, field, syrup-babyfood        0.150000   1.500  1.000
 2F0639

          Full comment: 2F06391

15001250 15   Corn, field, oil                   0.150000   1.000  1.000
 2F0639

          Full comment: 2F06391

15001251 15   Corn, field, oil-babyfood          0.150000   1.000  1.000
 2F0639

          Full comment: 2F06391

15001260 15   Corn, pop                          0.100000   1.000  1.000
 2F0639

          Full comment: 2F06391

15002260 15   Millet, grain                      0.100000   1.000  1.000
 Inadve

          Full comment: Inadvertent tol.

15002310 15   Oat, bran                          0.150000   1.000  1.000
 Inadve

          Full comment: Inadvertent tol.

15002320 15   Oat, flour                         0.100000   1.000  1.000
 Inadve

          Full comment: Inadvertent tol.

15002321 15   Oat, flour-babyfood                0.100000   1.000  1.000
 Inadve

          Full comment: Inadvertent tol.

15002330 15   Oat, groats/rolled oats            0.100000   1.000  1.000
 Inadve

          Full comment: Inadvertent tol.

15002331 15   Oat, groats/rolled oats-babyfood   0.100000   1.000  1.000
 Inadve

          Full comment: Inadvertent tol.

15003230 15   Rice, white                        0.100000   1.000  1.000
 Inadve

          Full comment: Inadvertent tol.

15003231 15   Rice, white-babyfood               0.100000   1.000  1.000
 Inadve

          Full comment: Inadvertent tol.

15003240 15   Rice, brown                        0.100000   1.000  1.000
 Inadve

          Full comment: Inadvertent tol.

15003241 15   Rice, brown-babyfood               0.100000   1.000  1.000
 Inadve

          Full comment: Inadvertent tol.

15003250 15   Rice, flour                        0.100000   1.000  1.000
 Inadve

          Full comment: Inadvertent tol.

15003251 15   Rice, flour-babyfood               0.100000   1.000  1.000
 Inadve

          Full comment: Inadvertent tol.

15003260 15   Rice, bran                         0.150000   1.000  1.000
 Inadve

          Full comment: Inadvertent tol.

15003261 15   Rice, bran-babyfood                0.150000   1.000  1.000
 Inadve

          Full comment: Inadvertent tol.

15003280 15   Rye, grain                         0.100000   1.000  1.000
 Inadve

          Full comment: Inadvertent tol.

15003290 15   Rye, flour                         0.100000   1.000  1.000
 Inadve

          Full comment: Inadvertent tol.

15003440 15   Sorghum, grain                     0.100000   1.000  1.000
 Inadve

          Full comment: Inadvertent tol.

15003450 15   Sorghum, syrup                     0.100000   1.000  1.000
 Inadve

          Full comment: Inadvertent tol.

15003810 15   Triticale, flour                   0.100000   1.000  1.000
 Inadve

          Full comment: Inadvertent tol.

15003811 15   Triticale, flour-babyfood          0.100000   1.000  1.000
 Inadve

          Full comment: Inadvertent tol.

15004010 15   Wheat, grain                       0.100000   1.000  1.000
 Inadve

          Full comment: Inadvertent tol.

15004011 15   Wheat, grain-babyfood              0.100000   1.000  1.000
 Inadve

          Full comment: Inadvertent tol.

15004020 15   Wheat, flour                       0.100000   1.000  1.000
 Inadve

          Full comment: Inadvertent tol.

15004021 15   Wheat, flour-babyfood              0.100000   1.000  1.000
 Inadve

          Full comment: Inadvertent tol.

15004030 15   Wheat, germ                        0.100000   1.000  1.000
 Inadve

          Full comment: Inadvertent tol.

15004040 15   Wheat, bran                        0.150000   1.000  1.000
 Inadve

          Full comment: Inadvertent tol.

15004050 15   Wild rice                          0.100000   1.000  1.000
 Inadve

          Full comment: Inadvertent tol.

20001630 20   Flaxseed, oil                      0.150000   1.000  1.000
 

20003640 20   Sunflower, seed                    0.200000   1.000  1.000
 

20003650 20   Sunflower, oil                     0.200000   1.000  1.000
 

20003651 20   Sunflower, oil-babyfood            0.200000   1.000  1.000
 

86010000 O    Water, direct, all sources         0.035800   1.000  1.000
 

86020000 O    Water, indirect, all sources       0.035800   1.000  1.000
 

95000190 O    Asparagus                          0.150000   1.000  1.000
 2E0650

          Full comment: 2E06500

95002630 O    Peanut                             0.200000   1.000  1.000
 0F0611

          Full comment: 0F06116

95002640 O    Peanut, butter                     0.200000   1.890  1.000
 0F0611

          Full comment: 0F06116

95002650 O    Peanut, oil                        0.200000   1.000  1.000
 0F0611

          Full comment: 0F06116

95002750 O    Peppermint                         0.300000   1.000  1.000
 1E0631

          Full comment: 1E06311

95002760 O    Peppermint, oil                    0.300000   1.000  1.000
 1E0631

          Full comment: 1E06311

95003520 O    Spearmint                          0.300000   1.000  1.000
 1E0631

          Full comment: 1E06311

95003530 O    Spearmint, oil                     0.300000   1.000  1.000
 1E0631

          Full comment: 1E06311

95003590 O    Strawberry                         0.150000   1.000  1.000
 

95003591 O    Strawberry-babyfood                0.150000   1.000  1.000
 

95003600 O    Strawberry, juice                  0.150000   1.000  1.000
 

95003601 O    Strawberry, juice-babyfood         0.150000   1.000  1.000
 

95003620 O    Sugarcane, sugar                   0.150000   1.000  1.000
 

95003621 O    Sugarcane, sugar-babyfood          0.150000   1.000  1.000
 

95003630 O    Sugarcane, molasses                0.200000   1.000  1.000
 

95003631 O    Sugarcane, molasses-babyfood       0.200000   1.000  1.000
 

95003800 O    Tomato, Tree                       0.150000   1.000  1.000
 

											

Attachment 2:  DEEM-FCID( Acute Exposure Estimates for the General
Population including Infants and Children.1

U.S. Environmental Protection Agency                                 
Ver. 2.02

DEEM-FCID ACUTE Analysis for SULFENTRAZONE                      
(1994-98 data)

Residue file: 129081-acute-2009-jml__01 DEC 2010.R98

    Adjustment factor #2 used.

Analysis Date: 12-01-2010/09:52:09    Residue file dated:
12-01-2010/09:50:36/8

Daily totals for food and foodform consumption used.

Run Comment: ""

========================================================================
=======

Summary calculations (per capita):

                    95th Percentile      99th Percentile      99.9th
Percentile

                   Exposure   % aRfD    Exposure   % aRfD    Exposure  
% aRfD 

                  ---------- --------  ---------- --------  ----------
--------

U.S. Population:

                    0.004347     0.17    0.007110     0.28    0.011882  
  0.48 

All infants:

                    0.009388     0.38    0.013235     0.53    0.020709  
  0.83 

Children 1-2 yrs:

                    0.008187     0.33    0.011436     0.46    0.018298  
  0.73 

Children 3-5 yrs:

                    0.007476     0.30    0.010856     0.43    0.017357  
  0.69 

Children 6-12 yrs:

                    0.005284     0.21    0.007704     0.31    0.010870  
  0.43 

Youth 13-19 yrs:

                    0.003695     0.15    0.005772     0.23    0.010982  
  0.44 

Adults 20-49 yrs:

                    0.003341     0.13    0.004837     0.19    0.008144  
  0.33 

Adults 50+ yrs:

                    0.002942     0.12    0.004081     0.16    0.006160  
  0.25 

Females 13-49 yrs:

                    0.003256     0.132    0.004506     0.18    0.007684 
   0.31 

1 The aPAD for the general population including infants and children =
2.5 mg/kg bw/day.  The aPAD for females 13-49 years old = 0.14 mg/kg
bw/day.

™ using an aPAD of 2.5 mg/kg bw/day.  The % aPAD reported in Table 3
was adjusted to account for the lower aPAD (0.14 mg/kg bw/day) for
females 13-49 years old using the following formula:  % aPAD =
(Exposure/aPAD)*100% = (0.003256/0.14)*100% = 2.3%.

Attachment 3:  DEEM-FCID( Chronic Residue File.

Filename: C:\Documents and Settings\jlangsda\My
Documents\Chemicals\Sulfentrazone\November 2010\Sent to
Reviewers\129081-chronic-2009-jml__01 DEC 2010.R98

Chemical: Sulfentrazone

RfD(Chronic): .1 mg/kg bw/day  NOEL(Chronic): 0 mg/kg bw/day

RfD(Acute): 2.5 mg/kg bw/day  NOEL(Acute):  0 mg/kg bw/day

Date created/last modified: 12-01-2010/09:51:00/8          Program ver.
2.03

------------------------------------------------------------------------
--------

  EPA    Crop                                   Def Res     Adj.Factors 
 Comment

  Code    Grp  Commodity Name                    (ppm)       #1    #2   

-------- ---- -------------------------------  ----------  ------ ------
 -------

01011900 1AB  Horseradish                        0.200000   1.000  1.000
 1E0631

          Full comment: 1E06311; TLT 0.10 ppm, exp. 12/31/05

01030150 1CD  Arrowroot, flour                   0.150000   1.000  1.000
 

01030151 1CD  Arrowroot, flour-babyfood          0.150000   1.000  1.000
 

01030170 1CD  Artichoke, Jerusalem               0.150000   1.000  1.000
 

01030820 1CD  Cassava                            0.150000   1.000  1.000
 

01030821 1CD  Cassava-babyfood                   0.150000   1.000  1.000
 

01031390 1CD  Dasheen, corm                      0.150000   1.000  1.000
 

01031660 1CD  Ginger                             0.150000   1.000  1.000
 

01031661 1CD  Ginger-babyfood                    0.150000   1.000  1.000
 

01031670 1CD  Ginger, dried                      0.150000   1.000  1.000
 

01032960 1C   Potato, chips                      0.150000   1.000  1.000
 

01032970 1C   Potato, dry (granules/ flakes)     0.150000   6.500  1.000
 

01032971 1C   Potato, dry (granules/ flakes)-b   0.150000   6.500  1.000
 

01032980 1C   Potato, flour                      0.150000   6.500  1.000
 

01032981 1C   Potato, flour-babyfood             0.150000   6.500  1.000
 

01032990 1C   Potato, tuber, w/peel              0.150000   1.000  1.000
 

01032991 1C   Potato, tuber, w/peel-babyfood     0.150000   1.000  1.000
 

01033000 1C   Potato, tuber, w/o peel            0.150000   1.000  1.000
 

01033001 1C   Potato, tuber, w/o peel-babyfood   0.150000   1.000  1.000
 

01033660 1CD  Sweet potato                       0.150000   1.000  1.000
 

01033661 1CD  Sweet potato-babyfood              0.150000   1.000  1.000
 

01033710 1CD  Tanier, corm                       0.150000   1.000  1.000
 

01033870 1CD  Turmeric                           0.150000   1.000  1.000
 

01034060 1CD  Yam, true                          0.150000   1.000  1.000
 

01034070 1CD  Yam bean                           0.150000   1.000  1.000
 

05010610 5A   Broccoli                           0.200000   1.000  1.000
 

05010611 5A   Broccoli-babyfood                  0.200000   1.000  1.000
 

05010620 5A   Broccoli, Chinese                  0.200000   1.000  1.000
 

05010640 5A   Brussels sprouts                   0.200000   1.000  1.000
 

05010690 5A   Cabbage                            0.200000   1.000  1.000
 1E0631

          Full comment: 1E06311

05010710 5A   Cabbage, Chinese, napa             0.200000   1.000  1.000
 1E0631

          Full comment: 1E06311

05010720 5A   Cabbage, Chinese, mustard          0.200000   1.000  1.000
 1E0631

          Full comment: 1E06311

05010830 5A   Cauliflower                        0.200000   1.000  1.000
 

05011960 5A   Kohlrabi                           0.200000   1.000  1.000
 

05020630 5B   Broccoli raab                      0.400000   1.000  1.000
 

05020700 5B   Cabbage, Chinese, bok choy         0.400000   1.000  1.000
 1E0631

          Full comment: 1E06311

05021170 5B   Collards                           0.400000   1.000  1.000
 

05021940 5B   Kale                               0.400000   1.000  1.000
 

05022290 5B   Mustard greens                     0.400000   1.000  1.000
 

05023180 5B   Rape greens                        0.400000   1.000  1.000
 

05023890 5B   Turnip, greens                     0.400000   1.000  1.000
 

06003470 6    Soybean, seed                      0.050000   1.000  1.000
 

06003480 6    Soybean, flour                     0.050000   1.000  1.000
 

06003481 6    Soybean, flour-babyfood            0.050000   1.000  1.000
 

06003490 6    Soybean, soy milk                  0.050000   1.000  1.000
 

06003491 6    Soybean, soy milk-babyfood or in   0.050000   1.000  1.000
 

06003500 6    Soybean, oil                       0.050000   1.000  1.000
 

06003501 6    Soybean, oil-babyfood              0.050000   1.000  1.000
 

06010430 6A   Bean, snap, succulent              0.150000   1.000  1.000
 

06010431 6A   Bean, snap, succulent-babyfood     0.150000   1.000  1.000
 

06012570 6A   Pea, edible podded, succulent      0.150000   1.000  1.000
 

06020310 6B   Bean, broad, succulent             0.150000   1.000  1.000
 

06020330 6B   Bean, cowpea, succulent            0.100000   1.000  1.000
 TLT, e

          Full comment: TLT, exp. 12/31/04

06020370 6B   Bean, lima, succulent              0.150000   1.000  1.000
 2E0649

          Full comment: 2E06498

06022550 6B   Pea, succulent                     0.150000   1.000  1.000
 

06022551 6B   Pea, succulent-babyfood            0.150000   1.000  1.000
 

06022590 6B   Pea, pigeon, succulent             0.150000   1.000  1.000
 

06030300 6C   Bean, black, seed                  0.150000   1.000  1.000
 2F0639

          Full comment: 2F06391

06030320 6C   Bean, broad, seed                  0.150000   1.000  1.000
 2F0639

          Full comment: 2F06391

06030340 6C   Bean, cowpea, seed                 0.150000   1.000  1.000
 2F0639

          Full comment: 2F06391

06030350 6C   Bean,  great northern, seed        0.150000   1.000  1.000
 2F0639

          Full comment: 2F06391

06030360 6C   Bean, kidney, seed                 0.150000   1.000  1.000
 2F0639

          Full comment: 2F06391

06030380 6C   Bean, lima, seed                   0.150000   1.000  1.000
 2F0639

          Full comment: 2F06391

06030390 6C   Bean, mung, seed                   0.150000   1.000  1.000
 2F0639

          Full comment: 2F06391

06030400 6C   Bean, navy, seed                   0.150000   1.000  1.000
 2F0639

          Full comment: 2F06391

06030410 6C   Bean, pink, seed                   0.150000   1.000  1.000
 2F0639

          Full comment: 2F06391

06030420 6C   Bean, pinto, seed                  0.150000   1.000  1.000
 2F0639

          Full comment: 2F06391

06030980 6C   Chickpea, seed                     0.150000   1.000  1.000
 2F0639

          Full comment: 2F06391

06030981 6C   Chickpea, seed-babyfood            0.150000   1.000  1.000
 2F0639

          Full comment: 2F06391

06030990 6C   Chickpea, flour                    0.150000   1.000  1.000
 2F0639

          Full comment: 2F06391

06031820 6C   Guar, seed                         0.150000   1.000  1.000
 2F0639

          Full comment: 2F06391

06031821 6C   Guar, seed-babyfood                0.150000   1.000  1.000
 2F0639

          Full comment: 2F06391

06032030 6C   Lentil, seed                       0.150000   1.000  1.000
 2F0639

          Full comment: 2F06391

06032560 6C   Pea, dry                           0.150000   1.000  1.000
 2F0639

          Full comment: 2F06391

06032561 6C   Pea, dry-babyfood                  0.150000   1.000  1.000
 2F0639

          Full comment: 2F06391

06032580 6C   Pea, pigeon, seed                  0.150000   1.000  1.000
 2F0639

          Full comment: 2F06391

08001480 8    Eggplant                           0.150000   1.000  1.000
 

08002340 8    Okra                               0.150000   1.000  1.000
 

08002700 8    Pepper, bell                       0.150000   1.000  1.000
 

08002701 8    Pepper, bell-babyfood              0.150000   1.000  1.000
 

08002710 8    Pepper, bell, dried                0.150000   1.000  1.000
 

08002711 8    Pepper, bell, dried-babyfood       0.150000   1.000  1.000
 

08002720 8    Pepper, nonbell                    0.150000   1.000  1.000
 New, S

          Full comment: New, Section 18

08002721 8    Pepper, nonbell-babyfood           0.150000   1.000  1.000
 New, S

          Full comment: New, Section 18

08002730 8    Pepper, nonbell, dried             0.150000   1.000  1.000
 New, S

          Full comment: New, Section 18

08003740 8    Tomatillo                          0.150000   1.000  1.000
 

08003750 8    Tomato                             0.150000   1.000  1.000
 

08003751 8    Tomato-babyfood                    0.150000   1.000  1.000
 

08003760 8    Tomato, paste                      0.150000   5.400  1.000
 

08003761 8    Tomato, paste-babyfood             0.150000   5.400  1.000
 

08003770 8    Tomato, puree                      0.150000   3.300  1.000
 

08003771 8    Tomato, puree-babyfood             0.150000   3.300  1.000
 

08003780 8    Tomato, dried                      0.150000  14.300  1.000
 

08003781 8    Tomato, dried-babyfood             0.150000  14.300  1.000
 

08003790 8    Tomato, juice                      0.150000   1.500  1.000
 

09010750 9A   Cantaloupe                         0.150000   1.000  1.000
 

09010800 9A   Casaba                             0.150000   1.000  1.000
 

09011870 9A   Honeydew melon                     0.150000   1.000  1.000
 

09013990 9A   Watermelon                         0.150000   1.000  1.000
 

09014000 9A   Watermelon, juice                  0.150000   1.000  1.000
 

15000250 15   Barley, pearled barley             0.100000   1.000  1.000
 Inadve

          Full comment: Inadvertent tol.

15000251 15   Barley, pearled barley-babyfood    0.100000   1.000  1.000
 Inadve

          Full comment: Inadvertent tol.

15000260 15   Barley, flour                      0.100000   1.000  1.000
 Inadve

          Full comment: Inadvertent tol.

15000261 15   Barley, flour-babyfood             0.100000   1.000  1.000
 Inadve

          Full comment: Inadvertent tol.

15000270 15   Barley, bran                       0.150000   1.000  1.000
 Inadve

          Full comment: Inadvertent tol.

15000650 15   Buckwheat                          0.100000   1.000  1.000
 Inadve

          Full comment: Inadvertent tol.

15000660 15   Buckwheat, flour                   0.100000   1.000  1.000
 Inadve

          Full comment: Inadvertent tol.

15001200 15   Corn, field, flour                 0.150000   1.000  1.000
 2F0639

          Full comment: 2F06391

15001201 15   Corn, field, flour-babyfood        0.150000   1.000  1.000
 2F0639

          Full comment: 2F06391

15001210 15   Corn, field, meal                  0.150000   1.000  1.000
 2F0639

          Full comment: 2F06391

15001211 15   Corn, field, meal-babyfood         0.150000   1.000  1.000
 2F0639

          Full comment: 2F06391

15001220 15   Corn, field, bran                  0.150000   1.000  1.000
 Inadve

          Full comment: Inadvertent tol.

15001230 15   Corn, field, starch                0.150000   1.000  1.000
 2F0639

          Full comment: 2F06391

15001231 15   Corn, field, starch-babyfood       0.150000   1.000  1.000
 2F0639

          Full comment: 2F06391

15001240 15   Corn, field, syrup                 0.150000   1.500  1.000
 2F0639

          Full comment: 2F06391

15001241 15   Corn, field, syrup-babyfood        0.150000   1.500  1.000
 2F0639

          Full comment: 2F06391

15001250 15   Corn, field, oil                   0.150000   1.000  1.000
 2F0639

          Full comment: 2F06391

15001251 15   Corn, field, oil-babyfood          0.150000   1.000  1.000
 2F0639

          Full comment: 2F06391

15001260 15   Corn, pop                          0.100000   1.000  1.000
 2F0639

          Full comment: 2F06391

15002260 15   Millet, grain                      0.100000   1.000  1.000
 Inadve

          Full comment: Inadvertent tol.

15002310 15   Oat, bran                          0.150000   1.000  1.000
 Inadve

          Full comment: Inadvertent tol.

15002320 15   Oat, flour                         0.100000   1.000  1.000
 Inadve

          Full comment: Inadvertent tol.

15002321 15   Oat, flour-babyfood                0.100000   1.000  1.000
 Inadve

          Full comment: Inadvertent tol.

15002330 15   Oat, groats/rolled oats            0.100000   1.000  1.000
 Inadve

          Full comment: Inadvertent tol.

15002331 15   Oat, groats/rolled oats-babyfood   0.100000   1.000  1.000
 Inadve

          Full comment: Inadvertent tol.

15003230 15   Rice, white                        0.100000   1.000  1.000
 Inadve

          Full comment: Inadvertent tol.

15003231 15   Rice, white-babyfood               0.100000   1.000  1.000
 Inadve

          Full comment: Inadvertent tol.

15003240 15   Rice, brown                        0.100000   1.000  1.000
 Inadve

          Full comment: Inadvertent tol.

15003241 15   Rice, brown-babyfood               0.100000   1.000  1.000
 Inadve

          Full comment: Inadvertent tol.

15003250 15   Rice, flour                        0.100000   1.000  1.000
 Inadve

          Full comment: Inadvertent tol.

15003251 15   Rice, flour-babyfood               0.100000   1.000  1.000
 Inadve

          Full comment: Inadvertent tol.

15003260 15   Rice, bran                         0.150000   1.000  1.000
 Inadve

          Full comment: Inadvertent tol.

15003261 15   Rice, bran-babyfood                0.150000   1.000  1.000
 Inadve

          Full comment: Inadvertent tol.

15003280 15   Rye, grain                         0.100000   1.000  1.000
 Inadve

          Full comment: Inadvertent tol.

15003290 15   Rye, flour                         0.100000   1.000  1.000
 Inadve

          Full comment: Inadvertent tol.

15003440 15   Sorghum, grain                     0.100000   1.000  1.000
 Inadve

          Full comment: Inadvertent tol.

15003450 15   Sorghum, syrup                     0.100000   1.000  1.000
 Inadve

          Full comment: Inadvertent tol.

15003810 15   Triticale, flour                   0.100000   1.000  1.000
 Inadve

          Full comment: Inadvertent tol.

15003811 15   Triticale, flour-babyfood          0.100000   1.000  1.000
 Inadve

          Full comment: Inadvertent tol.

15004010 15   Wheat, grain                       0.100000   1.000  1.000
 Inadve

          Full comment: Inadvertent tol.

15004011 15   Wheat, grain-babyfood              0.100000   1.000  1.000
 Inadve

          Full comment: Inadvertent tol.

15004020 15   Wheat, flour                       0.100000   1.000  1.000
 Inadve

          Full comment: Inadvertent tol.

15004021 15   Wheat, flour-babyfood              0.100000   1.000  1.000
 Inadve

          Full comment: Inadvertent tol.

15004030 15   Wheat, germ                        0.100000   1.000  1.000
 Inadve

          Full comment: Inadvertent tol.

15004040 15   Wheat, bran                        0.150000   1.000  1.000
 Inadve

          Full comment: Inadvertent tol.

15004050 15   Wild rice                          0.100000   1.000  1.000
 Inadve

          Full comment: Inadvertent tol.

20001630 20   Flaxseed, oil                      0.150000   1.000  1.000
 

20003640 20   Sunflower, seed                    0.200000   1.000  1.000
 

20003650 20   Sunflower, oil                     0.200000   1.000  1.000
 

20003651 20   Sunflower, oil-babyfood            0.200000   1.000  1.000
 

86010000 O    Water, direct, all sources         0.026000   1.000  1.000
 

86020000 O    Water, indirect, all sources       0.026000   1.000  1.000
 

95000190 O    Asparagus                          0.150000   1.000  1.000
 2E0650

          Full comment: 2E06500

95002630 O    Peanut                             0.200000   1.000  1.000
 0F0611

          Full comment: 0F06116

95002640 O    Peanut, butter                     0.200000   1.890  1.000
 0F0611

          Full comment: 0F06116

95002650 O    Peanut, oil                        0.200000   1.000  1.000
 0F0611

          Full comment: 0F06116

95002750 O    Peppermint                         0.300000   1.000  1.000
 1E0631

          Full comment: 1E06311

95002760 O    Peppermint, oil                    0.300000   1.000  1.000
 1E0631

          Full comment: 1E06311

95003520 O    Spearmint                          0.300000   1.000  1.000
 1E0631

          Full comment: 1E06311

95003530 O    Spearmint, oil                     0.300000   1.000  1.000
 1E0631

          Full comment: 1E06311

95003590 O    Strawberry                         0.150000   1.000  1.000
 

95003591 O    Strawberry-babyfood                0.150000   1.000  1.000
 

95003600 O    Strawberry, juice                  0.150000   1.000  1.000
 

95003601 O    Strawberry, juice-babyfood         0.150000   1.000  1.000
 

95003620 O    Sugarcane, sugar                   0.150000   1.000  1.000
 

95003621 O    Sugarcane, sugar-babyfood          0.150000   1.000  1.000
 

95003630 O    Sugarcane, molasses                0.200000   1.000  1.000
 

95003631 O    Sugarcane, molasses-babyfood       0.200000   1.000  1.000
 

95003800 O    Tomato, Tree                       0.150000   1.000  1.000
 

Attachment 4:  DEEM-FCID( Chronic Exposure Estimates.

U.S. Environmental Protection Agency                                
Ver. 2.00

DEEM-FCID Chronic analysis for SULFENTRAZONE                    (1994-98
data)

Residue file name: C:\Documents and Settings\jlangsda\My
Documents\Chemicals\Sulfentrazone\November 2010\Sent to
Reviewers\129081-chronic-2009-jml__01 DEC 2010.R98

                                                     Adjustment factor
#2 used.

Analysis Date 12-01-2010/10:00:17     Residue file dated:
12-01-2010/09:51:00/8

Reference dose (RfD, Chronic) = .1 mg/kg bw/day

========================================================================
=======

                    Total exposure by population subgroup

------------------------------------------------------------------------
-------

                                                    Total Exposure

                                        
-----------------------------------

          Population                         mg/kg             Percent
of   

           Subgroup                       body wt/day             Rfd   
   

--------------------------------------   -------------      
---------------

U.S. Population (total)                     0.001751                
1.8%

U.S. Population (spring season)             0.001760                
1.8%

U.S. Population (summer season)             0.001841                
1.8%

U.S. Population (autumn season)             0.001701                
1.7%

U.S. Population (winter season)             0.001700                
1.7%

Northeast region                            0.001667                
1.7%

Midwest region                              0.001810                
1.8%

Southern region                             0.001696                
1.7%

Western region                              0.001849                
1.8%

Hispanics                                   0.001922                
1.9%

Non-hispanic whites                         0.001704                
1.7%

Non-hispanic blacks                         0.001782                
1.8%

Non-hisp/non-white/non-black                0.002025                
2.0%

All infants (< 1 year)                      0.003117                
3.1%

Nursing infants                             0.001240                
1.2%

Non-nursing infants                         0.003829                
3.8%

Children 1-6  yrs                           0.003430                
3.4%

Children 7-12 yrs                           0.002286                
2.3%

Females 13-19 (not preg or nursing)         0.001519                
1.5%

Females 20+ (not preg or nursing)           0.001400                
1.4%

Females 13-50 yrs                           0.001534                
1.5%

Females 13+ (preg/not nursing)              0.001513                
1.5%

Females 13+ (nursing)                       0.001853                
1.9%

Males 13-19 yrs                             0.001796                
1.8%

Males 20+ yrs                               0.001485                
1.5%

Seniors 55+                                 0.001352                
1.4%

Children 1-2 yrs                            0.003565                
3.6%

Children 3-5 yrs                            0.003463                
3.5%

Children 6-12 yrs                           0.002404                
2.4%

Youth 13-19 yrs                             0.001660                
1.7%

Adults 20-49 yrs                            0.001492                
1.5%

Adults 50+ yrs                              0.001360                
1.4%

Females 13-49 yrs                           0.001451                
1.5%

------------------------------------------------------------------------
-------

Sulfentrazone	Dietary Exposure and Risk Assessment	           DP Number:
 D384090  	

PC Code:  129081

________________________________________________________________________
____________________

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