Document ID: EPA-HQ-OPP-2013-0138-0014
Agency: epa
Document Type: Supporting & Related Material
Title: 
Posted Date: 2015-05-18T04:00Z

FIRST AID

If swallowed

	Call a poison control center or doctor immediately for treatment
advice.

Have person sip a glass of water if able to swallow.

Do not induce vomiting unless told to do so by a poison control center
or doctor.

Do not give anything to an unconscious person.

If on skin or clothing	Take off contaminated clothing.

Rinse skin immediately with plenty of soap and water for 15-20 minutes.

Call a poison control center or doctor for treatment advice.

Have the product container or label with you when calling a poison
control center or doctor, or going for treatment.

HOT LINE NUMBER

For 24-Hour Medical Emergency Assistance (Human or Animal) 

Call 1-888-484-7546.

For Chemical Emergency, Spill, Leak, Fire or Accident, Call CHEMTREC
1-800-424-9300.

GROUP	  7	FUNGICIDE

ISOFETAMID 

TURF FUNGICIDE

ACTIVE INGREDIENT: Isofetamid*	36.0%

OTHER INGREDIENTS:	64.0%

Total	100.0%

*N-[1,1-dimethyl-2-[2-methyl-4-(1-methylethoxy)phenyl]-

2-oxoethyl]-3-methyl-2-thiophenecarboxamide 

Contains 3.33 pounds Isofetamid Per Gallon (400 grams per liter)

KEEP OUT OF REACH OF CHILDREN

CAUTION

See side panel for additional precautionary statements.

Read entire label carefully and use only as directed.

ISK Biosciences Corporation

7470 Auburn Road, Suite A

Concord, Ohio 44077 U.S.A.

EPA Reg. No. 	71512-EG 		EPA Est. No. 

Active Ingredient Made in Japan

Formulation Made in

Net Contents:  

PRECAUTIONARY STATEMENTS

HAZARDS TO HUMANS AND DOMESTIC ANIMALS

CAUTION

Harmful if swallowed or absorbed through skin.  Avoid contact with skin,
eyes or clothing.  Wash thoroughly with soap and water after handling
and before eating, drinking, chewing gum, using tobacco or using the
toilet. Remove and wash contaminated clothing before reuse.  

Personal Protective Equipment (PPE)

Applicators and other handlers must wear long-sleeved shirt and long
pants, socks, shoes, and chemical resistant gloves made of any
waterproof material.

Follow manufacturer’s instructions for cleaning/ maintaining PPE. If
no such instructions for washables, use detergent and hot water. Keep
and wash PPE separately from other laundry.

Engineering Control Statements

When handlers use closed systems, enclosed cabs, or aircraft in a manner
that meets the requirements listed in the Worker Protection Standard
(WPS) for agricultural pesticides [40 CFR 170.240(d)(4-6)], the handler
PPE requirements may be reduced or modified as specified in the WPS.

User Safety Recommendations

Users should:

Wash hands before eating, drinking, chewing gum, using tobacco or using
the toilet.

Remove clothing/PPE immediately if pesticide gets inside.  Then wash
thoroughly and put on clean clothing.

Remove PPE immediately after handling this product.  Wash the outside of
gloves before removing.  As soon as possible, wash thoroughly and change
into clean clothing.  

ENVIRONMENTAL HAZARDS

This pesticide is toxic to oysters. DO NOT apply directly to water, or
to areas where surface water is present or to intertidal areas below the
mean high water mark. DO NOT contaminate waters when disposing of
equipment washwaters or rinsate.  Do not apply when weather conditions
favor drift from the treated areas.  Drift and runoff may be hazardous
to aquatic organisms in water adjacent to treated areas.

AVOIDING SPRAY DRIFT AT THE APPLICATION SITE IS THE RESPONSIBILITY OF
THE APPLICATOR.  The interaction of many equipment-and-weather-related
factors determine the potential for spray drift.  The applicator is
responsible for considering all these factors when making decisions. 
Where states have more stringent regulations, they must be observed.

STORAGE AND DISPOSAL

DO NOT contaminate water, food or feed by storage or disposal.  

PESTICIDE STORAGE:  Store in original container, in a secured, dry, cool
place separate from fertilizer, food, and feed.  Avoid
cross-contamination with other pesticides.

PESTICIDE DISPOSAL:  Pesticide wastes may be hazardous.  Improper
disposal of excess pesticide, spray mixture or rinsate is a violation of
Federal law.  If these wastes cannot be disposed of by use according to
label instructions, contact your State Pesticide or Environmental
Control Agency or the Hazardous Waste representative at the nearest EPA
Regional Office for guidance.

CONTAINER HANDLING:  Nonrefillable container (equal to or less than 5
gallons). DO NOT reuse or refill this container.  Triple rinse container
(or equivalent) promptly after emptying.  Triple rinse as follows: Empty
the remaining contents into application equipment or a mix tank and
drain for 10 seconds after the flow begins to drip.  Fill the container
¼ full with water and recap.  Shake for 10 seconds.  Pour rinsate into
application equipment or a mix tank or store rinsate for later use or
disposal.  Drain for 10 seconds after the flow begins to drip.  Repeat
this procedure two more times.  Then offer for recycling if available,
or puncture and dispose of in a sanitary landfill, or by incineration
or, if allowed by state and local authorities, by burning.  If burned,
stay out of smoke.

Nonrefillable container (greater than 5 gallons). DO NOT reuse or refill
this container.  Triple rinse container (or equivalent) promptly after
emptying. Triple rinse as follows: Empty the remaining contents into
application equipment or a mix tank.  Fill the container ¼ full with
water.  Recap and tighten closures.  Tip container on its side and roll
it back and forth, ensuring at least one complete revolution, for 30
seconds.  Stand the container on its end and tip it back and forth
several times.  Turn the container over onto its other end and tip it
back and forth several times.  Empty rinsate into application equipment
or a mix tank or store rinsate for later use or disposal.  Repeat this
procedure two more times. Then offer for recycling if available, or
puncture and dispose of in a sanitary landfill, or by incineration or,
if allowed by state and local authorities, by burning.  If burned, stay
out of smoke.

DIRECTIONS FOR USE

It is a violation of Federal law to use this product in a manner
inconsistent with its labeling.

DO NOT apply this product in a way that will contact workers or other
persons, either directly or through drift.  Only protected handlers may
be in the area during application.  For any requirements specific to
your State or Tribe, consult the agency responsible for pesticide
regulation.

FAILURE TO FOLLOW THE USE DIRECTIONS AND PRECAUTIONS ON THIS LABEL MAY
RESULT IN PLANT INJURY OR POOR DISEASE CONTROL.

ISOFETAMID is a flowable suspension concentrate for control of diseases
on turf areas associated with golf courses (greens, tees and fairways),
sod farms, seed farms, college and professional sports fields,
residential and commercial lawns.  Intended for use only by professional
applicators.

AGRICULTURAL USE REQUIREMENTS

Use this product only in accordance with its labeling and with the
Worker Protection Standard, 40 CFR Part 170.  This Standard contains
requirements for the protection of agricultural workers on farms,
forests, nurseries, and greenhouses and handlers of agricultural
pesticides.  It contains requirements for training, decontamination,
notification, and emergency assistance.  It also contains specific
instructions and exceptions pertaining to the statements on this label
about personal protective equipment (PPE), and restricted-entry
interval.  The requirements in this box only apply to uses of this
product that are covered by the Worker Protection Standard.

DO NOT enter or allow worker entry into treated areas during the
restricted entry interval (REI) of twelve (12) hours. 

PPE required for early entry into treated areas that is permitted under
the Worker Protection Standard and that involves contact with anything
that has been treated, such as plants, soil, or water, is: coveralls,
chemical resistant gloves made of any waterproof material, shoes plus
socks.

Sod and seed farms, commercial greenhouses and nurseries are within the
scope of the Worker Protection Standard.

NON-AGRICULTURAL USE REQUIREMENTS

The requirements in this box apply to uses of this product that are not
within the scope of the Worker Protection Standard for agricultural
pesticides, 40 CFR Part 170.  The WPS applies when this product is used
to produce agricultural plants on farms, forests, nurseries, or
greenhouses.  Turfgrasses on golf courses and other non-residential turf
areas such as industrial parks, tank farms, professionally managed
college and professional sports fields, commercial lawns and ornamental
landscapes are not within the scope of the Worker Protection Standard.  

Keep children, pets, and unprotected persons out of the treated area
until sprays have dried. 

PRODUCT INFORMATION

ISOFETAMID is a broad-spectrum fungicide with preventative, systemic and
curative properties for the control of dollar spot on turfgrasses. 
ISOFETAMID should be used in a regularly scheduled preventative spray
program and used in rotation with products with a different mode of
action, such as triazoles, ergosterol biosynthesis inhibitors (QoI) or
benzimidazoles.  For control of other diseases not listed on this label,
ISOFETAMID may be tank mixed with other fungicides.  Tank mixes should
follow the use instructions on both labels for application rate and
application timings.  Failure to follow these instructions may results
in inferior disease control and/or phytotoxicity.

Although ISOFETAMID has been evaluated on several turfgrass cultivars,
varieties and hybrids with no indication of phytotoxicity, neither the
manufacturer nor seller have determined adequate tolerance on all
turfgrass under all conditions.  The user should determine if ISOFETAMID
can be used safely for commercial use by applying the labeled rate to a
small test area under conditions to be expected and monitor for adverse
effects before applying ISOFETAMID to the targeted area. 

USE RESTRICTIONS

Do not apply more than 3.2 fl oz/1000 sq ft per year or 140 fl oz per
acre. This is equal to 8 applications at the low rate (0.452 lb
a.i./A/application) or 6 applications at the high rate (0.567 lb
a.i./A/application).

Do not apply ISOFETAMID through any type of irrigation system

Do not apply ISOFETAMID by aerial application

Intended for use only by professional applicators.

Integrated Pest Management

ISOFETAMID is an excellent disease control agent when used according to
label directions for control of dollar spot on turfgrass.  Although
ISOFETAMID has preventative, systemic and curative activity, it should
be applied as a protectant fungicide before visible symptoms of the
disease occur.  

Depending upon the level of disease pressure, good protection of the
turfgrass can be expected over a period of 14 days.

ISOFETAMID is recommended for use as part of an Integrated Pest
Management (IPM) program, which may include the use of disease-resistant
crop varieties, cultural practices, biological disease control agents,
pest scouting and disease forecasting systems aimed at preventing
economic pest damage.  Practices known to reduce disease development
should be followed.  Consult your state cooperative extension service or
local agricultural authorities for additional IPM strategies established
in your area.  ISOFETAMID may be used in State Agricultural Extension
advisory (disease forecasting) programs that recommend application
timing based upon environmental factors that favor disease development.

RESISTANCE MANAGEMENT

Some plant pathogens are known to develop resistance to products used
repeatedly for disease control.  ISOFETAMID’s mode/target site of
action is complex II; succinate-dehydrogenase, FRAC Group 7.  A disease
management program that includes alternation or tank mixes between
ISOFETAMID and other labeled fungicides that have a different mode of
action and/or control pathogens not controlled with ISOFETAMID is
essential to prevent disease resistant pathogens populations from
developing.  ISOFETAMID should not be utilized continuously nor tank
mixed with fungicides that have shown to have developed fungal
resistance to the target disease.

Since pathogens differ in their potential to develop resistance to
fungicides, follow the directions outlined in the “Directions For
Use” section of this label for specific resistance management
strategies.  Consult with your Federal or State Cooperative Extension
Service representatives for guidance on the proper use of ISOFETAMID in
programs that seek to minimize the occurrence of disease resistance. 
ISOFETAMID is not cross-resistant with other classes of fungicides that
have different modes of action.

MIXING AND SPRAYING

For maximum efficacy ISOFETAMID should be applied prior to or in the
very early stages of disease development.  ISOFETAMID must be applied at
the label rates and timings listed in the Directions for Use section in
2 to 4 gallons of water per 1000 square feet (87 to 174 gallons per
acre).

Slowly invert container several times to assure uniform mixture of
formulation before adding this product to the spray tank. The required
amount of ISOFETAMID 400SC should be added slowly into the spray tank
during filling.  With concentrate sprays, pre-mix the required amount of
ISOFETAMID 400SC in a clean container and add to the spray tank as it is
being filled.  Keep agitator running when filling spray tank and during
spray operations.  DO NOT allow spray mixture to stand overnight or for
prolonged periods.  Prepare only the amount of spray required for
immediate use.  Spraying equipment should be thoroughly cleaned
immediately after the application.

Under conditions favorable for disease development, the highest rate
specified and shortest application interval should be used.  

ISOFETAMID may be applied with all types of spray equipment normally
used for ground applications on turfgrasses.

TANK MIX COMPATIBILITY

ISOFETAMID is physically compatible (no nozzle or screen blockage) with
many products labeled for control of diseases and insects on
turfgrasses. Read and follow all manufacturers label precautions and
restrictions for the tank mix companion product. It is the
applicator’s responsibility to ensure that the companion product is
EPA approved for use on the intended site. ISOFETAMID is generally
compatible with other insecticides, fungicides, adjuvants, fertilizers
and micronutrient products provided sufficient free water is available
for dispersion of all the tank mix products. Under some conditions, the
use of adjuvants and/or surfactants at the rate of 0.025% to 0.1% of the
spray tank volume may improve the performance of ISOFETAMID.  However,
the physical compatibility of ISOFETMAID with tank mix partners must be
evaluated before use. Conduct a jar test with intended tank-mix
pesticides prior to preparation of large volumes. Use the following
procedure: 1) Pour the recommended proportions of the products into a
suitable container of water; 2) Mix thoroughly and; 3) Allow to stand
for 5 minutes.  If the combination remains mixed or can be re-mixed
readily, it is considered physically compatible. Any physical
incompatibility in the jar test indicates that ISOFETAMID should not be
used in the tank-mix.

User should note that not all turf varieties have been tested with all
possible tank mix combinations.  Thus the combination should be tested
for turf safety on a small portion of the turf to ensure that a
phytotoxic response will not occur.



Table 1.  Application Rates and Intervals

Disease	Rate 

(fl oz/1000 sq ft)	Rate 

(fl oz / acre)	Application

Interval

(days)	Comments

Dollar spot

 (Sclerotinia homoeocarpa)	0.4 to 0.5	 17.4 to 21.8 (0.452 to 0.567 lb.
a.i./A	14	Apply as a preventative treatment prior to or in the very
early stage of development.  Use the highest rate during periods of
prolonged favorable disease conditions.  Do not apply more than two
consecutive applications of ISOFETAMID or other Group 7 containing
fungicides before rotating to a registered fungicide with a different
mode of action. Do not apply the next application of ISOFETAMID within
28 days of the previous two consecutive ISOFETAMID applications.

Table 2.  Dilution Table for Applications

	fl oz of ISOFETAMID per 100 gallons of spray solutions

Use Rate 

(fl oz per 1000 sq ft)	Spray Volume

2 gallons per 1000 sq ft	Spray Volume

3 gallons per 1000 sq ft	Spray Volume

4 gallons per 1000 sq ft

0.4	20 fl oz/ 100 gal	13.3 fl oz/ 100 gal	10 fl oz/ 100 gal

0.5	25 fl oz/ 100 gal	16.7 fl oz/ 100 gal	12.5 fl oz/ 100 gal



WARRANTY AND LIMITATION OF DAMAGES

Seller warrants to those persons lawfully acquiring title to this
product that at the time of first sale of this product by Seller that
this product conformed to its chemical description and was reasonably
fit for the purposes stated on the label when used in accordance with
Seller’s directions under normal conditions of use.  To the extent
consistent with applicable law, Buyers and users of this product assume
the risk of any use contrary to such directions.  EXCEPT AS PROVIDED
ELSEWHERE IN WRITING CONTAINING AN EXPRESS REFERENCE TO THIS WARRANTY
AND LIMITATION OF DAMAGES, SELLER MAKES NO OTHER EXPRESS OR 

ISK Biosciences Corporation

7470 Auburn Road, Suite A

Concord, Ohio 44077 U.S.A.

IMPLIED WARRANTY OR GUARANTY, INCLUDING ANY OTHER EXPRESS OR IMPLIED
WARRANTY OF FITNESS OR

OF MERCHANTABILITY, AND NO AGENT OF SELLER IS 

AUTHORIZED TO DO SO.  In no event shall Seller’s liability for any
breach of warranty or guaranty exceed the purchase price of the product
as to which a claim is made. To the extent consistent with applicable
law, Buyers and users of this product are responsible for all loss or
damage from use or handling of this product which results from
conditions beyond the control of Seller, including, but not limited to,
incompatibility with other products unless otherwise expressly provided
in Directions for Use of this product, weather conditions, cultural
practices, moisture conditions or other environmental conditions outside
of the ranges that are generally recognized as being conducive to good
agricultural and/or horticultural practices.

ISOFETAMID - 03202015

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