cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7941812
title: Genetic aberrations in multiple myeloma characterized by cIg-FISH: a Brazilian context

description: Genetic abnormalities are critical prognostic factors for patients diagnosed with multiple myeloma (MM). This retrospective, multicenter study aimed to contribute with the genetic and clinical characterization of MM patients in a country with continental dimensions such as Brazil. Genetic abnormalities were assessed by cIg-fluorescent in situ hybridization (cIg-FISH) in a series of 152 MM patients (median age 55 years, 58.5% men). Overall, genetic abnormalities were detected in 52.7% (80/152) of patients. A 14q32 rearrangement was detected in 33.5% (n=51), including t(11;14), t(4;14) and t(14;16) in 18.4, 14.1, and 1% of cases, respectively. del(13q) was identified in 42.7% (n=65) of patients, of whom 49.2% (32/65) presented a concomitant 14q32 rearrangement. del(17p) had a frequency of 5.2% (n=8). del(13q) was associated with high plasma cell burden (≥50%, P=0.02), and del(17p) with advanced ISS stages (P=0.05) and extramedullary disease (P=0.03). t(4;14) was associated with advanced Durie-Salmon stages (P=0.008), renal insufficiency (P=0.01) and was more common in patients over 60 years old. This study reports similar frequencies of genetic abnormalities to most series worldwide, whereas the t(14;16) and del(17p), two high risk factors for newly diagnosed patients, exhibited lower frequencies. Our results expand the knowledge on the molecular features of MM in Brazil, a country where innovative therapies that could overcome a poor prognosis for some genetic abnormalities are not always available.
DOI: 10.6084/m9.figshare.7941815
title: Application of ashes as filling in reprocessed polypropylene: thermomechanical properties of composites

description: Abstract The life cycle of a product depends to a great extent on its reuse and ease of recycling. This work had developed of composite materials of reprocessed polypropylene composites with rice husk ash (RHA) and sugarcane bagasse ash (SBA) through the coextrusion and injection processes as main purpose. The polymeric matrix was reprocesed until six generations by the injection technique. The reprocessed PP was mixed in 80:20 proportions with respect to filler mineral, using maleic anhydride as coupling agent in a coextrusion machine. The new series of composite materials were analyzed thermal, mechanical, rheological and morphologically. The incorporation of ashes in the PP matrix achieved characteristics of improved tensile strength, conserving the thermal properties. For this reason, this work presents an alternative for the manufacture of composite materials from post-industrial waste.
DOI: 10.6084/m9.figshare.7941818
title: Incidence of Conduction Disorders and Requirements for Permanent Pacemaker After Transcatheter Aortic Valve Implantation

description: Abstract Background: Transcatheter aortic valve implantation (TAVI) has become a therapeutic option for high-risk or non-operable patients with severe symptomatic aortic stenosis. Atrioventricular conduction disturbances requiring permanent pacemaker (PPM) are a common and clinically important complication. Objectives: To evaluate the incidence of conduction disorders (CDs) after TAVI and the need for subsequent PPM implantation. To identify the predictors of postoperative PPM implantation. Methods: Retrospective study. All patients who underwent TAVI in a public hospital from December/2011 to June/2016 were included. Multivariate analysis was conducted to establish the predictor of permanent pacemaker implantation. Survival curves were constructed by the Kaplan-Meyer method. Statistically significant variables were those with p value &lt; 0.05. Results: 64 patients with AS underwent TAVI. Eleven patients were excluded. TAVI induced a new CD in 40 (77%) of the remaining 53 patients. The most common new CDs were 3rd degree AV block (32%) and left bundle branch block (30%). Sixteen patients (30,2%) underwent PPM implantation during the index hospitalization. On univariate analysis the risk factors for PPM implantation were CoreValve® use (OR: 1,76; P = 0,005), larger prosthesis implantation (P = 0,015), presence of a QRS ≥ 120 ms (OR: 5,62; P = 0,012), and 1st degree AV block (OR: 13; P = 0.008). On multivariate analysis the presence of 1st degree AV block predicted the need for PPM. Conclusion: TAVI induced CDs requiring PPM in 30% of the patients. The presence of 1st degree AV block predicted the need for PPM.
DOI: 10.6084/m9.figshare.7941812.v1
title: Genetic aberrations in multiple myeloma characterized by cIg-FISH: a Brazilian context

description: Genetic abnormalities are critical prognostic factors for patients diagnosed with multiple myeloma (MM). This retrospective, multicenter study aimed to contribute with the genetic and clinical characterization of MM patients in a country with continental dimensions such as Brazil. Genetic abnormalities were assessed by cIg-fluorescent in situ hybridization (cIg-FISH) in a series of 152 MM patients (median age 55 years, 58.5% men). Overall, genetic abnormalities were detected in 52.7% (80/152) of patients. A 14q32 rearrangement was detected in 33.5% (n=51), including t(11;14), t(4;14) and t(14;16) in 18.4, 14.1, and 1% of cases, respectively. del(13q) was identified in 42.7% (n=65) of patients, of whom 49.2% (32/65) presented a concomitant 14q32 rearrangement. del(17p) had a frequency of 5.2% (n=8). del(13q) was associated with high plasma cell burden (≥50%, P=0.02), and del(17p) with advanced ISS stages (P=0.05) and extramedullary disease (P=0.03). t(4;14) was associated with advanced Durie-Salmon stages (P=0.008), renal insufficiency (P=0.01) and was more common in patients over 60 years old. This study reports similar frequencies of genetic abnormalities to most series worldwide, whereas the t(14;16) and del(17p), two high risk factors for newly diagnosed patients, exhibited lower frequencies. Our results expand the knowledge on the molecular features of MM in Brazil, a country where innovative therapies that could overcome a poor prognosis for some genetic abnormalities are not always available.
DOI: 10.6084/m9.figshare.7941815.v1
title: Application of ashes as filling in reprocessed polypropylene: thermomechanical properties of composites

description: Abstract The life cycle of a product depends to a great extent on its reuse and ease of recycling. This work had developed of composite materials of reprocessed polypropylene composites with rice husk ash (RHA) and sugarcane bagasse ash (SBA) through the coextrusion and injection processes as main purpose. The polymeric matrix was reprocesed until six generations by the injection technique. The reprocessed PP was mixed in 80:20 proportions with respect to filler mineral, using maleic anhydride as coupling agent in a coextrusion machine. The new series of composite materials were analyzed thermal, mechanical, rheological and morphologically. The incorporation of ashes in the PP matrix achieved characteristics of improved tensile strength, conserving the thermal properties. For this reason, this work presents an alternative for the manufacture of composite materials from post-industrial waste.
DOI: 10.6084/m9.figshare.7941809
title: Interprofessional Practice in the Emergency Service: specific and shared assignments of nurses

description: ABSTRACT Objective: To map and categorize, according to the Nursing Interventions Classification (NIC), the specific assignments of the nurses and to identify the assignments shared with doctors and physiotherapists in the Emergency Service. Method: Descriptive exploratory study, carried out in two phases: first, the analysis of dissertations /theses from the database of the Center for Studies and Research of the Brazilian Nursing Association; Second, the use of the Delphi Technique to reach the consensus about which assignments were specific to the nurse and which were shared with physiotherapists and doctors. Results: The results were 45.7% for specific to the nurses, 14.2% for shared with physiotherapists and/or doctors, and in 40% (n=42) there was no consensus about the sharing of assignments. Conclusion: The sharing of actions among professionals shows an increase in the scope of the practice of professions and the constitution of a common sphere of work, but the high number of assignments with no consensus among specialists can be a potential factor in conflicts due to the lack of definition of these assignments.
DOI: 10.6084/m9.figshare.7941794
title: Quality control in the different stages of producing red blood cell concentrate from dogs

description: ABSTRACT The objective of this study was to perform a quality control assessment of red blood cells after standardization of the blood production stages. For this purpose, separation of the blood components to obtain red blood cells, the storage of the blood packets and an evaluation of blood quality were performed. The mean (± SD) volume, globular volume, hemoglobin and hemolysis percentage of the red blood cell concentrate were 299.77±30.08mL, 60.87±2.60%, 20.57±0.93g/DL and 0.09±0.07%, respectively. The means (± SD) of the volume, globular volume, total hemoglobin percentage of hemolysis and hemoglobin per unit of packed red blood cells after the storage period (8.83±6.73 days) were 57.55±3.01%, 20.30±0.89 0, 20±0.12%, and 60.90±7.65. The red blood cell packets were within the parameters of quality control established by Health Ministry legislation in humans and allow us to conclude that the standardization of blood production stages involves the selection of donors until the end of storage and is necessary to produce quality red blood cells. Quality control aims to find possible flaws in the procedures to be repaired, increasing transfusion safety.
DOI: 10.6084/m9.figshare.7941803
title: Risk perception in the use of personal protective equipment against noise-induced hearing loss

description: Abstract Although there are many approaches to occupational noise exposure, the analysis of individual perception of the worker and its implications on behavior is still a topic that is rarely addressed. A state-of-the-art survey of publications that relate the variables associated with exposure to physical risk of noise in the workplace with the use of hearing protection equipment is presented reducing this gap. After that, a sample of 278 industrial workers exposed to sound pressure levels above 80 dB (A) was collected to examine the relationship between the perception of occupational noise and the use of personal hearing equipment. By a statistical analysis of the identified variables, the direct and indirect effects of a set of factors affecting the use of the equipment were analyzed. Thus, the perception of noise exposure risk by workers is an important predictor of the use of hearing protection equipment.
DOI: 10.6084/m9.figshare.7941806
title: PERFORMANCE OF THE CATALYTIC MEMBRANE REACTORS OF DIFFERENT PORE SIZE WITH PALLADIUM AS CATALYTIC PHASE IN HYDROGENATION AND OXIDATION REACTIONS

description: ABSTRACT The catalytic membrane reactors (CMR) were prepared using commercial Hollow Fiber Membranes of corundum with 4 nm or 1400 nm pores and impregnated with palladium. The tests performed were phenol hydrogenation, hydrogen peroxide generation to oxidize phenol by advanced oxidation processes and chromium (VI) reduction. Reactions were performed in aqueous solution, at mild temperature and under atmospheric pressure. For all tests, the hydrogen passed through the membrane to be activated with palladium. The test with phenol showed that, in the absence of oxygen, the activated hydrogen reacts with the organic matter, leading to the formation of hydrogenated products; in the presence of oxygen, active hydrogen reacts with oxygen to form hydrogen peroxide and subsequently hydroxyl radicals that attack the organic matter until its mineralization. Furthermore, the CMR is capable of reducing chromium (VI) to chromium (III). The CMRs of smaller pore size presented better performance in all reactions.
DOI: 10.6084/m9.figshare.7941809.v1
title: Interprofessional Practice in the Emergency Service: specific and shared assignments of nurses

description: ABSTRACT Objective: To map and categorize, according to the Nursing Interventions Classification (NIC), the specific assignments of the nurses and to identify the assignments shared with doctors and physiotherapists in the Emergency Service. Method: Descriptive exploratory study, carried out in two phases: first, the analysis of dissertations /theses from the database of the Center for Studies and Research of the Brazilian Nursing Association; Second, the use of the Delphi Technique to reach the consensus about which assignments were specific to the nurse and which were shared with physiotherapists and doctors. Results: The results were 45.7% for specific to the nurses, 14.2% for shared with physiotherapists and/or doctors, and in 40% (n=42) there was no consensus about the sharing of assignments. Conclusion: The sharing of actions among professionals shows an increase in the scope of the practice of professions and the constitution of a common sphere of work, but the high number of assignments with no consensus among specialists can be a potential factor in conflicts due to the lack of definition of these assignments.
DOI: 10.6084/m9.figshare.7941788
title: BACTERICIDAL EFFECTIVENESS OF FREEZE-CAST CERAMIC FILTERS IMPREGNATED WITH SILVER NANOPARTICLES

description: ABSTRACT This work aimed to produce freeze-cast pellets of porous ceramic filters of alumina and kaolinite impregnated with silver nanoparticles and to test the efficiency of bactericidal effects. Silver nanoparticles were characterized by average particle size, zeta potential and TEM. After impregnation, leached water was analyzed by graphite furnace atomic absorption spectrometry (GFAAS) that showed an efficiency of more than 99.9% in silver impregnation. From SEM/EDS, it was possible to observe that the pellets have a homogeneous distribution of silver nanoparticles. A halo of inhibition detected by the disc diffusion test shows a strong bactericidal effect of the filters.
DOI: 10.6084/m9.figshare.7941794.v1
title: Quality control in the different stages of producing red blood cell concentrate from dogs

description: ABSTRACT The objective of this study was to perform a quality control assessment of red blood cells after standardization of the blood production stages. For this purpose, separation of the blood components to obtain red blood cells, the storage of the blood packets and an evaluation of blood quality were performed. The mean (± SD) volume, globular volume, hemoglobin and hemolysis percentage of the red blood cell concentrate were 299.77±30.08mL, 60.87±2.60%, 20.57±0.93g/DL and 0.09±0.07%, respectively. The means (± SD) of the volume, globular volume, total hemoglobin percentage of hemolysis and hemoglobin per unit of packed red blood cells after the storage period (8.83±6.73 days) were 57.55±3.01%, 20.30±0.89 0, 20±0.12%, and 60.90±7.65. The red blood cell packets were within the parameters of quality control established by Health Ministry legislation in humans and allow us to conclude that the standardization of blood production stages involves the selection of donors until the end of storage and is necessary to produce quality red blood cells. Quality control aims to find possible flaws in the procedures to be repaired, increasing transfusion safety.
DOI: 10.6084/m9.figshare.7941803.v1
title: Risk perception in the use of personal protective equipment against noise-induced hearing loss

description: Abstract Although there are many approaches to occupational noise exposure, the analysis of individual perception of the worker and its implications on behavior is still a topic that is rarely addressed. A state-of-the-art survey of publications that relate the variables associated with exposure to physical risk of noise in the workplace with the use of hearing protection equipment is presented reducing this gap. After that, a sample of 278 industrial workers exposed to sound pressure levels above 80 dB (A) was collected to examine the relationship between the perception of occupational noise and the use of personal hearing equipment. By a statistical analysis of the identified variables, the direct and indirect effects of a set of factors affecting the use of the equipment were analyzed. Thus, the perception of noise exposure risk by workers is an important predictor of the use of hearing protection equipment.
DOI: 10.6084/m9.figshare.7941806.v1
title: PERFORMANCE OF THE CATALYTIC MEMBRANE REACTORS OF DIFFERENT PORE SIZE WITH PALLADIUM AS CATALYTIC PHASE IN HYDROGENATION AND OXIDATION REACTIONS

description: ABSTRACT The catalytic membrane reactors (CMR) were prepared using commercial Hollow Fiber Membranes of corundum with 4 nm or 1400 nm pores and impregnated with palladium. The tests performed were phenol hydrogenation, hydrogen peroxide generation to oxidize phenol by advanced oxidation processes and chromium (VI) reduction. Reactions were performed in aqueous solution, at mild temperature and under atmospheric pressure. For all tests, the hydrogen passed through the membrane to be activated with palladium. The test with phenol showed that, in the absence of oxygen, the activated hydrogen reacts with the organic matter, leading to the formation of hydrogenated products; in the presence of oxygen, active hydrogen reacts with oxygen to form hydrogen peroxide and subsequently hydroxyl radicals that attack the organic matter until its mineralization. Furthermore, the CMR is capable of reducing chromium (VI) to chromium (III). The CMRs of smaller pore size presented better performance in all reactions.
DOI: 10.6084/m9.figshare.7941785
title: Nuts and Cardiovascular Diseases: Focus on Brazil Nuts

description: Abstract Cardiovascular diseases (CVD) are the main cause of death globally and most CVD can be prevented by addressing their risk factors, such as an unhealthy diet. Many authors have studied the benefits of nut consumption on CVD. Nuts contain high amounts of vegetable protein, unsaturated fatty acids, dietary fibers, vitamins, minerals and many other bioactive compounds, like phytosterols and phenolic compounds, which are able to reduce cholesterol levels and promote antioxidant and anti-inflammatory effects, thereby reducing cardiovascular risks. This review aims to describe studies involving the consumption of nuts, including Brazil nuts and CVD risk factors with positive results in the improvement of lipid profile, glucose metabolism, vascular function, and inflammatory and oxidative stress biomarkers.
DOI: 10.6084/m9.figshare.7941779
title: Talk the talk and walk the walk! Association between Weekly Exercise Load and Knowledge about Recommendations for Fighting Innactivity

description: Abstract Background: The World Health Organization (WHO) recommends as a weekly "target dose" of exercise 150 minutes of moderate exercise or 75 minutes of intense exercise. Public health policies have prioritized the practice of exercise as a strategy for disease prevention and health promotion, with health professionals as their main promoters. Objective: To assess the interaction between the amount of exercise per week and the knowledge about recommendations for fighting a sedentary lifestyle among health care professionals attending a congress of cardiology. Methods: Participants of the 2017 Rio de Janeiro Society of Cardiology Congress were interviewed. Knowledge about the World Health Organization (WHO) recommendations for fighting a sedentary lifestyle was assessed by asking participants the question: "How much weekly exercise is recommended by the WHO?" Responders were stratified by the weekly exercise load reported. A multivariate logistic model was created to determine independent predictors of knowledge. Results: A total of 426 participants were interviewed (45.5% men, median age 31 years, 37.8% physicians, 65.8% of the physicians were cardiologists). The overall knowledge level was 44.6%; 38.1%, 52.7% and 56.6% among non-physicians, non-cardiologists and cardiologists, respectively (p = 0.002). Of all participants, 21.8% were inactive, 15% were lightly active, 34.7% moderately active and 28.4% highly active, and the percentage of individuals who gave a correct answer to the question on exercise recommendations was 30.1%, 42%, 48% and 52.9% respectively (p &lt; 0.0001). In the multivariate analysis, being highly active (OR = 2.25, IC95%, 1.238 - 4.089), moderately active (OR = 1.93, IC 95% 1.105 - 3.39) and being a cardiologist (OR = 2.01, IC 95% 1.243 - 3,267) were predictors of knowledge. Conclusions: There was a linear association between exercise level and knowledge about the WHO recommendations on exercise. Policies to stimulate the practice of exercise among health professionals can positively impact campaigns for reducing sedentary lifestyle in the general population.
DOI: 10.6084/m9.figshare.7941788.v1
title: BACTERICIDAL EFFECTIVENESS OF FREEZE-CAST CERAMIC FILTERS IMPREGNATED WITH SILVER NANOPARTICLES

description: ABSTRACT This work aimed to produce freeze-cast pellets of porous ceramic filters of alumina and kaolinite impregnated with silver nanoparticles and to test the efficiency of bactericidal effects. Silver nanoparticles were characterized by average particle size, zeta potential and TEM. After impregnation, leached water was analyzed by graphite furnace atomic absorption spectrometry (GFAAS) that showed an efficiency of more than 99.9% in silver impregnation. From SEM/EDS, it was possible to observe that the pellets have a homogeneous distribution of silver nanoparticles. A halo of inhibition detected by the disc diffusion test shows a strong bactericidal effect of the filters.
DOI: 10.6084/m9.figshare.7941773
title: Rheological properties of low-density polyethylene filled with hydrophobic Co(Ni)-Al layered double hydroxides

description: Abstract Cobalt/aluminum and nickel/aluminum layered double hydroxide (LDH - M+2:Al molar ratio of 3:1) were intercalated with dodecylsulphate (DDS), laurate (LAU), stearate (STE) and palmitate (PAL) and used as filler in low-density polyethylene (LDPE) in percentages between 0.2 and 7.0wt%. After injection molding, the samples were submitted to morphological characterization by scanning electron microscopy (SEM), analysis of thermal behavior by differential scanning calorimetry (DSC) and investigation of rheological properties. All Co/Al-LDPE samples showed the formation of a high temperature polymer crystal domain, induced by the LDH filler. The rheological properties indicated in general a reduction of shear modulus due to incompatibility between some regions of LDH and LDPE, which promoted phase separation. However, interaction with the LDH surface indicated higher affinity of the Ni/Al-LDH for the LDPE compared to Co/Al-LDH, forming permanent networks.
DOI: 10.6084/m9.figshare.7941776
title: Fourteen Years’ Survival After Batista Operation: The Short History of a Long Journey

description: Abstract A 41-year-old man with end-stage heart failure due to nonischemic dilated cardiomyopathy was submitted to the Batista procedure as an alternative to heart transplantation. With surgery, the patient showed progressive clinical amelioration, achieving long-term stable NYHA functional class II, despite gradual dilation of the heart chambers. Persistent atrial fibrillation appeared on the last year of life, his clinical condition deteriorated, and the patient died 14 years, four months, and 13 days after the operation. To the best of our knowledge this seems to be the longest reported survival for a patient submitted to Batista operation.