cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.29875332.v1
title: Individual patient data meta-analysis of NEPA versus aprepitant-based antiemetic regimens for preventing chemotherapy-induced nausea and vomiting

description: Because no conclusive data demonstrate superiority among NK<sub>1</sub> receptor antagonists (RA), existing antiemetic guidelines regard them as interchangeable. This individual patient data (IPD) meta-analysis compared the efficacy of NEPA (netupitant/fosnetupitant) and aprepitant/fosaprepitant-based regimens in preventing chemotherapy-induced nausea and vomiting (CINV). Head-to-head comparative studies published between 2003 and 2022 that evaluated antiemetic prophylaxis of aprepitant or fosaprepitant versus oral or intravenous (IV) NEPA in patients with various cancers receiving highly (HEC) or moderately emetogenic chemotherapy (MEC) were identified through a literature search. We combined individual patient data to assess complete response (no emesis/no rescue medication) and no significant nausea using a two-stage approach. A total of six studies involving 2,767 patients were included evaluating NEPA plus dexamethasone versus aprepitant/fosaprepitant plus any 5-HT<sub>3</sub>RA plus dexamethasone for patients with cancer receiving HEC/MEC. Complete response and no significant nausea rates were similar during the acute (0–24 h) phase but NEPA showed significantly higher rates than aprepitant during the delayed ( &gt; 24–120 h) and overall (0–120 h) phases and on Days 3–5 following chemotherapy. Improved CINV prevention was observed with NEPA-based regimens, particularly during Days 3–5, highlighting its potential for managing prolonged nausea and vomiting associated with emerging anticancer targeted therapies. This study examined two types of medicine to help cancer patients feel less sick during chemotherapy. Both types try to stop nausea and vomiting. One kind is called NEPA, and the other is called aprepitant. Both include drugs taken by mouth or given through an IV. All patients also took other common medicines to help with side effects. The researchers looked at six studies with a total of 2,767 patients. They wanted to see which medicine worked better. On the first day of chemotherapy, both types worked about the same. But in the days after chemotherapy, NEPA worked better. It helped prevent vomiting and more severe nausea. It also meant fewer people needed extra medicine to feel better. This improvement was true from day 2 to day 5 after treatment. The study shows that NEPA may give better long-term relief from chemotherapy side effects, which may be especially helpful for patients who are using newer cancer drugs that can cause longer-lasting nausea.
DOI: 10.6084/m9.figshare.29875825
title: Postoperative nomogram for predicting involved lymph node in differentiated thyroid carcinoma: an observational study

description: This study aims to develop a comprehensive nomogram to accurately predict differentiated thyroid cancer (DTC) involved lymph node, enabling the personalization of treatment plans and optimizing patient outcomes. The nomogram was developed through an analysis of data obtained from derivation cohorts. To identify independent predictors of involved lymph node, we utilized the Least Absolute Shrinkage and Selection Operator (LASSO) method in conjunction with multivariable logistic regression. These predictive factors were subsequently integrated into the nomogram’s design. To ensure the tool’s robustness and clinical applicability, we assessed its discriminative ability, calibration, and clinical utility in both the derivation cohort and an independent validation cohort. The identification of four key parameters – Thyroglobulin, Lymphocyte count, BRAF<sup>V600E</sup>, and the number of tumor foci – emerged as robust predictors of involved lymph node. The nomogram demonstrated outstanding performance across calibration, discrimination, and clinical applicability, with predictive accuracies of 0.992 in the derivation cohort and 0.920 in the validation cohort. Peripheral lymphocyte counts have been found to correlate with involved lymph node in DTC patients. A nomogram tailored specifically for predicting involved lymph node in DTC guides personalized postoperative radioactive iodine (RAI) and plays a critical role in the preoperative assessment. Lymph node involvement is a big dealwhen figuring out how serious someone’s thyroid cancer is. It affects threeimportant medical decisions: 1.How much of the thyroid to remove duringsurgery. 2. Whether to use radioactive iodine treatment after surgery. 3. Howoften to check for cancer returning later Doctors now use something called”nomograms” - which are like scoring charts – to help predict whatmight happen to patients. This study created a special scoring chart just forthyroid cancer patients, to predict if their cancer has spread to lymph nodes.This helps doctors create personalized treatment plans. Using special math methods, we foundfour main things that predict lymph node involvement: Thyroglobulin levels (aprotein made by the thyroid), Number of certain white blood cells(lymphocytes), Whether the cancer has a specific gene change (BRAF<sup>V600E</sup>mutation), Number of separate cancer spots in the thyroid. We put these fourfactors into our scoring chart. Then we tested it thoroughly on two differentgroups of patients to make sure it works well. An interesting discovery: Patients withmore lymphocytes were less likely to have lymph node involvement. This mightmean having a stronger immune system helps fight cancer spread. This scoringchart helps doctors make better decisions, like: planning exactly which partsto remove during surgery, giving the right amount of radiation treatment aftersurgery, creating personalized follow-up schedules to watch for cancerreturning.
DOI: 10.6084/m9.figshare.29875825.v1
title: Postoperative nomogram for predicting involved lymph node in differentiated thyroid carcinoma: an observational study

description: This study aims to develop a comprehensive nomogram to accurately predict differentiated thyroid cancer (DTC) involved lymph node, enabling the personalization of treatment plans and optimizing patient outcomes. The nomogram was developed through an analysis of data obtained from derivation cohorts. To identify independent predictors of involved lymph node, we utilized the Least Absolute Shrinkage and Selection Operator (LASSO) method in conjunction with multivariable logistic regression. These predictive factors were subsequently integrated into the nomogram’s design. To ensure the tool’s robustness and clinical applicability, we assessed its discriminative ability, calibration, and clinical utility in both the derivation cohort and an independent validation cohort. The identification of four key parameters – Thyroglobulin, Lymphocyte count, BRAF<sup>V600E</sup>, and the number of tumor foci – emerged as robust predictors of involved lymph node. The nomogram demonstrated outstanding performance across calibration, discrimination, and clinical applicability, with predictive accuracies of 0.992 in the derivation cohort and 0.920 in the validation cohort. Peripheral lymphocyte counts have been found to correlate with involved lymph node in DTC patients. A nomogram tailored specifically for predicting involved lymph node in DTC guides personalized postoperative radioactive iodine (RAI) and plays a critical role in the preoperative assessment. Lymph node involvement is a big dealwhen figuring out how serious someone’s thyroid cancer is. It affects threeimportant medical decisions: 1.How much of the thyroid to remove duringsurgery. 2. Whether to use radioactive iodine treatment after surgery. 3. Howoften to check for cancer returning later Doctors now use something called”nomograms” - which are like scoring charts – to help predict whatmight happen to patients. This study created a special scoring chart just forthyroid cancer patients, to predict if their cancer has spread to lymph nodes.This helps doctors create personalized treatment plans. Using special math methods, we foundfour main things that predict lymph node involvement: Thyroglobulin levels (aprotein made by the thyroid), Number of certain white blood cells(lymphocytes), Whether the cancer has a specific gene change (BRAF<sup>V600E</sup>mutation), Number of separate cancer spots in the thyroid. We put these fourfactors into our scoring chart. Then we tested it thoroughly on two differentgroups of patients to make sure it works well. An interesting discovery: Patients withmore lymphocytes were less likely to have lymph node involvement. This mightmean having a stronger immune system helps fight cancer spread. This scoringchart helps doctors make better decisions, like: planning exactly which partsto remove during surgery, giving the right amount of radiation treatment aftersurgery, creating personalized follow-up schedules to watch for cancerreturning.
DOI: 10.6084/m9.figshare.29831284
title: Enhancing short-term recovery after gastric cancer surgery: an information–motivation–behavioral skills (IMB) model with nutritional support

description: To evaluate the short-term efficacy of an Information – Motivation – Behavioral Skills (IMB) model-based intervention combined with perioperative nutritional support in improving postoperative recovery in patients undergoing radical gastrectomy for gastric cancer. In this randomized controlled trial, 250 gastric cancer patients were allocated to either an intervention group (IMB model + individualized nutritional support, n = 125) or a control group (standard care, n = 125). The 15-day intervention targeted key recovery dimensions: sleep quality, nutritional status, pain, psychological well-being, and quality of life (QoL). Compared to controls, the intervention group showed significantly greater improvements in Pittsburgh Sleep Quality Index (PSQI) scores (−2.16 ± 0.74 vs. −1.32 ± 0.69), serum albumin levels (+5.56 ± 1.43 g/L vs. +2.03 ± 1.21 g/L), and global QoL based on the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30; +21.14 ± 6.91 vs. +9.04 ± 5.87; all P &lt; 0.001). Pain (Visual Analog Scale), anxiety (Self-Rating Anxiety Scale), and depression (Self-Rating Depression Scale) scores also improved significantly. IMB-guided psychosocial intervention with tailored nutritional support significantly enhanced short-term recovery. Further studies are needed to validate long-term efficacy.
DOI: 10.6084/m9.figshare.29831284.v1
title: Enhancing short-term recovery after gastric cancer surgery: an information–motivation–behavioral skills (IMB) model with nutritional support

description: To evaluate the short-term efficacy of an Information – Motivation – Behavioral Skills (IMB) model-based intervention combined with perioperative nutritional support in improving postoperative recovery in patients undergoing radical gastrectomy for gastric cancer. In this randomized controlled trial, 250 gastric cancer patients were allocated to either an intervention group (IMB model + individualized nutritional support, n = 125) or a control group (standard care, n = 125). The 15-day intervention targeted key recovery dimensions: sleep quality, nutritional status, pain, psychological well-being, and quality of life (QoL). Compared to controls, the intervention group showed significantly greater improvements in Pittsburgh Sleep Quality Index (PSQI) scores (−2.16 ± 0.74 vs. −1.32 ± 0.69), serum albumin levels (+5.56 ± 1.43 g/L vs. +2.03 ± 1.21 g/L), and global QoL based on the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30; +21.14 ± 6.91 vs. +9.04 ± 5.87; all P &lt; 0.001). Pain (Visual Analog Scale), anxiety (Self-Rating Anxiety Scale), and depression (Self-Rating Depression Scale) scores also improved significantly. IMB-guided psychosocial intervention with tailored nutritional support significantly enhanced short-term recovery. Further studies are needed to validate long-term efficacy.
DOI: 10.3535/wc4-f92-ygh
title: Copepoda Milne Edwards, 1840

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.15468/dl.grdwtb
title: Occurrence Download

description: A dataset containing 5639 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Echium creticum"
 ]
}

 The dataset includes 5639 records from 169 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0015768-250827131500795/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.27291492
title: Maastrichtian palaeoenvironments and palaeoclimate reconstruction in southern South America (Patagonia, Argentina) based on fossil fungi and algae using open data resources

description: The use of non-pollen palynomorphs (NPP), particularly fossil fungi and algae, as palaeobiological proxies for Late Cretaceous palaeoenvironmental and palaeoclimatic reconstructions of warm-to-hot greenhouse conditions, can enhance our understanding of climate change impacts on modern Patagonian environments. This study aimed to reconstruct the Maastrichtian palaeoenvironment and palaeoclimate in the Cañadón Asfalto Basin (CAB, Chubut Province) by testing these NPPs as proxies using the Nearest Living Relative method (NLR). Moreover, using modern ecological requirements from open-source databases, such as GBIF and processing it with an open-source, cross-platform tool like QGIS, linked with Köppen-Geiger shapefiles, provided evidence of climate-driven palaeo-distribution patterns of fungal and algal diversity at CAB. Applying modern ecological requirements and biogeographic distribution data, we reconstructed the palaeoclimate as temperate with evenly distributed precipitation and warm summers, corresponding to the Cfb climate zone in Köppen-Geiger classifications. Additionally, our methodology produced reliable results regarding Cenozoic floras’ physiognomies based on fossil fungi, revealing a transition from sparsely wooded areas with palms and prairies to complex forest ecosystems with palms, deciduous trees, and shrubland. Furthermore, testing Cretaceous algae with the NLR method, for the first time, provided comprehensive insights into past water body characteristics, including trophic state and water quality.
DOI: 10.6084/m9.figshare.27291492.v1
title: Maastrichtian palaeoenvironments and palaeoclimate reconstruction in southern South America (Patagonia, Argentina) based on fossil fungi and algae using open data resources

description: The use of non-pollen palynomorphs (NPP), particularly fossil fungi and algae, as palaeobiological proxies for Late Cretaceous palaeoenvironmental and palaeoclimatic reconstructions of warm-to-hot greenhouse conditions, can enhance our understanding of climate change impacts on modern Patagonian environments. This study aimed to reconstruct the Maastrichtian palaeoenvironment and palaeoclimate in the Cañadón Asfalto Basin (CAB, Chubut Province) by testing these NPPs as proxies using the Nearest Living Relative method (NLR). Moreover, using modern ecological requirements from open-source databases, such as GBIF and processing it with an open-source, cross-platform tool like QGIS, linked with Köppen-Geiger shapefiles, provided evidence of climate-driven palaeo-distribution patterns of fungal and algal diversity at CAB. Applying modern ecological requirements and biogeographic distribution data, we reconstructed the palaeoclimate as temperate with evenly distributed precipitation and warm summers, corresponding to the Cfb climate zone in Köppen-Geiger classifications. Additionally, our methodology produced reliable results regarding Cenozoic floras’ physiognomies based on fossil fungi, revealing a transition from sparsely wooded areas with palms and prairies to complex forest ecosystems with palms, deciduous trees, and shrubland. Furthermore, testing Cretaceous algae with the NLR method, for the first time, provided comprehensive insights into past water body characteristics, including trophic state and water quality.
DOI: 10.6084/m9.figshare.27239267
title: The biogeographic history of the allokotosaurian archosauromorphs in the Triassic of Pangaea

description: Allokotosauria (Trilophosauridae + Azendohsauridae) is a clade of Early – Late Triassic quadruped, sprawling archosauromorphs with diverse dietary habits, known from Madagascar, India, Morocco, North America, and Europe. We conducted the first quantitative biogeographic analysis of the clade to reconstruct its ancestral areas and dispersal events. The results estimated the India + Tanzania area as ancestral for Allokotosauria. Eastern North America was reconstructed as the ancestral area of Trilophosauridae, implying an Early Triassic Southern to Northern Hemisphere dispersal. Subsequently, trilophosaurids were restricted to the Northern Hemisphere, and at least two dispersal events from Europe to western North America are estimated during the early Anisian and probably during the early Carnian, respectively. Azendohsauridae retained the ancestral area of India + Tanzania during much of its evolutionary history. Two dispersal events to western and eastern North America, respectively, are reconstructed during the Carnian – early Norian, likely during or in the aftermath of the Carnian Pluvial Episode (CPE). This pattern mirrors that of early dinosaurs, which were restricted to the Southern Hemisphere with dispersals to the Northern Hemisphere not recorded until the end of the CPE. This study informs about biogeographic patterns involved in the biotic recovery after the end-Permian mass extinction and the early evolutionary radiation of Archosauromorpha.
DOI: 10.6084/m9.figshare.27239267.v1
title: The biogeographic history of the allokotosaurian archosauromorphs in the Triassic of Pangaea

description: Allokotosauria (Trilophosauridae + Azendohsauridae) is a clade of Early – Late Triassic quadruped, sprawling archosauromorphs with diverse dietary habits, known from Madagascar, India, Morocco, North America, and Europe. We conducted the first quantitative biogeographic analysis of the clade to reconstruct its ancestral areas and dispersal events. The results estimated the India + Tanzania area as ancestral for Allokotosauria. Eastern North America was reconstructed as the ancestral area of Trilophosauridae, implying an Early Triassic Southern to Northern Hemisphere dispersal. Subsequently, trilophosaurids were restricted to the Northern Hemisphere, and at least two dispersal events from Europe to western North America are estimated during the early Anisian and probably during the early Carnian, respectively. Azendohsauridae retained the ancestral area of India + Tanzania during much of its evolutionary history. Two dispersal events to western and eastern North America, respectively, are reconstructed during the Carnian – early Norian, likely during or in the aftermath of the Carnian Pluvial Episode (CPE). This pattern mirrors that of early dinosaurs, which were restricted to the Southern Hemisphere with dispersals to the Northern Hemisphere not recorded until the end of the CPE. This study informs about biogeographic patterns involved in the biotic recovery after the end-Permian mass extinction and the early evolutionary radiation of Archosauromorpha.
DOI: 10.3535/qjx-wr9-ael
title: Animalia

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/wdp-mnv-3p1
title: Copepoda Milne Edwards, 1840

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/f5z-l6v-g9l
title: Copepoda Milne Edwards, 1840

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/z0t-1ej-t34
title: Ostracoda Latreille, 1802

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/zz9-wcs-lwq
title: Ostracoda Latreille, 1802

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/43r-qfl-6k4
title: Copepoda Milne Edwards, 1840

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/8x4-3e6-e41
title: Copepoda Milne Edwards, 1840

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/brx-8bw-akx
title: Ostracoda Latreille, 1802

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/ygv-cpw-194
title: Ostracoda Latreille, 1802

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/3f1-9qw-7e6
title: Animalia

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/y7c-0wl-8je
title: Copepoda Milne Edwards, 1840

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/dr4-hcw-pvs
title: Ostracoda Latreille, 1802

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/np2-ljz-5ty
title: Ostracoda Latreille, 1802

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/vwd-wj6-p4b
title: Copepoda Milne Edwards, 1840

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/zcl-emf-257
title: Ostracoda Latreille, 1802

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/a15-qtb-6qh
title: Ostracoda Latreille, 1802

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/dlf-k78-a6q
title: Ostracoda Latreille, 1802

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/0l0-4fn-jp9
title: Ostracoda Latreille, 1802

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/0qd-gt8-ay1
title: Copepoda Milne Edwards, 1840

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/szj-69g-846
title: Ostracoda Latreille, 1802

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/whn-ang-gmp
title: Ostracoda Latreille, 1802

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/0jg-qwz-eb2
title: Copepoda Milne Edwards, 1840

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/dek-5sw-hfn
title: Copepoda Milne Edwards, 1840

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/pkf-3eh-4hm
title: Ostracoda Latreille, 1802

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/3c2-x34-cfh
title: Decapoda

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.15468/dl.jae6er
title: Occurrence Download

description: A dataset containing 66 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Onobrychis gracilis gracilis"
 ]
}

 The dataset includes 66 records from 14 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0015769-250827131500795/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.3535/xgm-477-mpk
title: Decapoda

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/wsa-g95-e4k
title: Ostracoda Latreille, 1802

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/c3a-rs5-8b7
title: Ostracoda Latreille, 1802

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.