cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.3123985.v2
title: COFINS: UMA ANÁLISE TRIBUTÁRIA DA TERCEIRIZAÇÃO

description: Through a remote view of labor law is sought to enrich the debate about “"ACTIVITIES SHARING" demonstrating the lack of productivity of the strident speech, the inability to hear and following attempts to demonstrate the difficulty in defining what is core business . Advancing at work seeks to demonstrate how the state encouraged first by fiscal means and then with encouragement the opening of micro and small businesses a flattening of the means of production, which in other words is nothing more than an "ACTIVITIES SHARING"of the core business . Finally seek once again demonstrating unproductive shallow criticism and the need for research in sectors which indeed can suffer from a careless regulation of "ACTIVITIES SHARING".
DOI: 10.6084/m9.figshare.3123985.v1
title: COFINS.pdf

description: Through a remote view of labor law is sought to enrich the debate about “"ACTIVITIES SHARING" demonstrating the lack of productivity of the strident speech, the inability to hear and following attempts to demonstrate the difficulty in defining what is core business . Advancing at work seeks to demonstrate how the state encouraged first by fiscal means and then with encouragement the opening of micro and small businesses a flattening of the means of production, which in other words is nothing more than an "ACTIVITIES SHARING"of the core business . Finally seek once again demonstrating unproductive shallow criticism and the need for research in sectors which indeed can suffer from a careless regulation of "ACTIVITIES SHARING".
DOI: 10.6084/m9.figshare.3124030.v2
title: Elevational Variation in Soil Amino Acid and Inorganic Nitrogen Concentrations in Taibai Mountain, China

description: The raw data for Fig 1-6. Fig.1. Concentrations of the different extractable N (A), free amino acids (B) and hydrolyzable amino acids (C) in the thirteen sampled elevations. Error bars represent standard error (n=3). Fig. 2. Compositions of soil hydrolyzable amino acids in the thirteen sampled elevations. Error bars represent standard error (n=3). Fig. 3. Elevational variations of the PC1 (A) and PC2 (B) score along a montane gradient. The best-fit lines, F values, goodness of fit (r) and p-values are provided. Fig.4. Simple linear regression of the relationships between the composition of individual amino acids contained in PC1 and elevation. The best-fit lines, F values, goodness of fit (r) and p-values are provided. Fig. 5. Proportions of the neutral, basic, acidic, and sulfur amino acids accounting for soil total hydrolyzable amino acids in the thirteen sampled elevations. Fig. 6. Mean concentrations of soil total N, total hydrolyzable N, hydrolyzable amino acids and un-hydrolyzable N (A), and their corresponding proportions that accounted for soil total N (B) across the thirteen sampled elevations. Error bars represent standard error (n=13).
DOI: 10.6084/m9.figshare.3123931
title: Data from: A synthesis of transplant experiments and ecological niche models suggests that range limits are often niche limits

description: This fileset contains scripts, input files and intermediate output files for an analysis of whether species geographic range limits are niche limits based on ecological niche models and over-the-edge transplant experiments.
DOI: 10.6084/m9.figshare.3123931.v1
title: Data from: A synthesis of transplant experiments and ecological niche models suggests that range limits are often niche limits

description: This fileset contains scripts, input files and intermediate output files for an analysis of whether species geographic range limits are niche limits based on ecological niche models and over-the-edge transplant experiments.
DOI: 10.6084/m9.figshare.3123847
title: short paper ISSS proceedings 2013 anthony et al.docx

description: This is the short paper presented at the 2013 International Society for the Social Studies. It was later further developed into a published manuscript. The link to the final paper is below.
DOI: 10.6084/m9.figshare.3123847.v1
title: short paper ISSS proceedings 2013 anthony et al.docx

description: This is the short paper presented at the 2013 International Society for the Social Studies. It was later further developed into a published manuscript. The link to the final paper is below.
DOI: 10.6084/m9.figshare.3123814
title: Supplementary Table S3 from the Electrically conductive pili of Geobacter species are a recently evolved feature for extracellular electron transfer

description: Supplementary Table showing accession numbers of genomes analyzed in this paper. Genome sequences were either obtained from NCBI or from IMG<br>
DOI: 10.6084/m9.figshare.3123715
title: Supplementary Table S1 from the Electrically conductive pili of Geobacter species are a recently evolved feature for extracellular electron transfer

description: Excel file with lists of pilin genes used for analysis in paper " The Electrically Conductive Pili of <i>Geobacter </i>Species<i> </i>are a Recently Evolved Feature for Extracellular Electron Transfer"
DOI: 10.6084/m9.figshare.3123814.v1
title: Supplementary Table S2

description: Supplementary Table showing accession numbers of genomes analyzed in this paper. Genome sequences were either obtained from NCBI or from IMG<br>
DOI: 10.6084/m9.figshare.3123814.v3
title: Supplementary Table S3 from the Electrically conductive pili of Geobacter species are a recently evolved feature for extracellular electron transfer

description: Supplementary Table showing accession numbers of genomes analyzed in this paper. Genome sequences were either obtained from NCBI or from IMG<br>
DOI: 10.6084/m9.figshare.3123715.v2
title: Supplementary Table S1 from the Electrically conductive pili of Geobacter species are a recently evolved feature for extracellular electron transfer

description: Excel file with lists of pilin genes used for analysis in paper " The Electrically Conductive Pili of <i>Geobacter </i>Species<i> </i>are a Recently Evolved Feature for Extracellular Electron Transfer"
DOI: 10.6084/m9.figshare.3123814.v2
title: Supplementary Table S2 from the Electrically conductive pili of Geobacter species are a recently evolved feature for extracellular electron transfer

description: Supplementary Table showing accession numbers of genomes analyzed in this paper. Genome sequences were either obtained from NCBI or from IMG<br>
DOI: 10.6084/m9.figshare.3123715.v1
title: Supplementary Table S1

description: Excel file with lists of pilin genes used for analysis in paper " The Electrically Conductive Pili of <i>Geobacter </i>Species<i> </i>are a Recently Evolved Feature for Extracellular Electron Transfer"
DOI: 10.6084/m9.figshare.3123667
title: ORCID Update (presentation to the Iowa State University Library Advisory Council)

description: These are the slides which accompanied a presentation given to the Iowa State University Library Advisory Council on January 15th, 2016. Assistance in preparing these slides was provided by Emma Molls.<br>
DOI: 10.6084/m9.figshare.3123685
title: Mobile technologies in medical education: AMEE Guide No. 105

description: Mobile technologies (including handheld and wearable devices) have the potential to enhance learning activities from basic medical undergraduate education through residency and beyond. In order to use these technologies successfully, medical educators need to be aware of the underpinning socio-theoretical concepts that influence their usage, the pre-clinical and clinical educational environment in which the educational activities occur, and the practical possibilities and limitations of their usage. This Guide builds upon the previous AMEE Guide to e-Learning in medical education by providing medical teachers with conceptual frameworks and practical examples of using mobile technologies in medical education. The goal is to help medical teachers to use these concepts and technologies at all levels of medical education to improve the education of medical and healthcare personnel, and ultimately contribute to improved patient healthcare. This Guide begins by reviewing some of the technological changes that have occurred in recent years, and then examines the theoretical basis (both social and educational) for understanding mobile technology usage. From there, the Guide progresses through a hierarchy of institutional, teacher and learner needs, identifying issues, problems and solutions for the effective use of mobile technology in medical education. This Guide ends with a brief look to the future.
DOI: 10.6084/m9.figshare.3123661
title: ORCID Update (presentation to the Iowa State University Library Liaisons)

description: These are the slides from a presentation given to the Iowa State University Library Liaisons meeting. The presentation was given twice, once on March 22, 2016 and again on March 23, 2016. This is a revised version of a presentation made to the Iowa State University Library Advisory Council on January 15, 2016. Assistance in preparing these slides was given by Emma Molls.<br>
DOI: 10.6084/m9.figshare.3123685.v1
title: Mobile technologies in medical education: AMEE Guide No. 105

description: Mobile technologies (including handheld and wearable devices) have the potential to enhance learning activities from basic medical undergraduate education through residency and beyond. In order to use these technologies successfully, medical educators need to be aware of the underpinning socio-theoretical concepts that influence their usage, the pre-clinical and clinical educational environment in which the educational activities occur, and the practical possibilities and limitations of their usage. This Guide builds upon the previous AMEE Guide to e-Learning in medical education by providing medical teachers with conceptual frameworks and practical examples of using mobile technologies in medical education. The goal is to help medical teachers to use these concepts and technologies at all levels of medical education to improve the education of medical and healthcare personnel, and ultimately contribute to improved patient healthcare. This Guide begins by reviewing some of the technological changes that have occurred in recent years, and then examines the theoretical basis (both social and educational) for understanding mobile technology usage. From there, the Guide progresses through a hierarchy of institutional, teacher and learner needs, identifying issues, problems and solutions for the effective use of mobile technology in medical education. This Guide ends with a brief look to the future.
DOI: 10.6084/m9.figshare.3123640
title: public data.xls

description: The original data about the ROS1 rearragement research in the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China<br>
DOI: 10.6084/m9.figshare.3123667.v3
title: ORCID Update (presentation to the Iowa State University Library Advisory Council)

description: These are the slides which accompanied a presentation given to the Iowa State University Library Advisory Council on January 15th, 2016. Assistance in preparing these slides was provided by Emma Molls.<br>
DOI: 10.6084/m9.figshare.3123532
title: Combination Intervention with Anti-CD20 Monoclonal Antibodies and IL-10 Genes in Prevention of TID in NOD Mice

description: Type 1 diabetes (T1D) is an autoimmune disease (AID) and its main features include progressive pancreatic β cell damages and absolute insufficient endogenous insulin secretion. Now we adopted the “Cocktail” therapy to investigate the preventive effects of combination intervention to T1D in NOD mice. This is serological,immunohistochemical, qPCR and WB related data.
DOI: 10.6084/m9.figshare.3123661.v3
title: ORCID Update (presentation to the Iowa State University Library Liaisons)

description: These are the slides from a presentation given to the Iowa State University Library Liaisons meeting. The presentation was given twice, once on March 22, 2016 and again on March 23, 2016. This is a revised version of a presentation made to the Iowa State University Library Advisory Council on January 15, 2016. Assistance in preparing these slides was given by Emma Molls.<br>
DOI: 10.6084/m9.figshare.3123463
title: Raw larval collection data for all 15 replicates, including the relative abundance of Anopheles and Culex collected and the estimated time taken to collect one larva for each replicate.

description: Includes: trial location, trap type, trap handler, number of mosquitoes collected, proportions of mosquitoes collected and estimated total time.
DOI: 10.6084/m9.figshare.3123532.v2
title: Combination Intervention with Anti-CD20 Monoclonal Antibodies and IL-10 Genes in Prevention of TID in NOD Mice

description: Type 1 diabetes (T1D) is an autoimmune disease (AID) and its main features include progressive pancreatic β cell damages and absolute insufficient endogenous insulin secretion. Now we adopted the “Cocktail” therapy to investigate the preventive effects of combination intervention to T1D in NOD mice. This is serological,immunohistochemical, qPCR and WB related data.
DOI: 10.6084/m9.figshare.3123463.v1
title: Raw larval collection data for all 15 replicates, including the relative abundance of Anopheles and Culex collected and the estimated time taken to collect one larva for each replicate.

description: Includes: trial location, trap type, trap handler, number of mosquitoes collected, proportions of mosquitoes collected and estimated total time.
DOI: 10.6084/m9.figshare.3123532.v1
title: Table1-7.xls

description: Type 1 diabetes (T1D) is an autoimmune disease (AID) and its main features include progressive pancreatic β cell damages and absolute insufficient endogenous insulin secretion. Now we adopted the “Cocktail” therapy to investigate the preventive effects of combination intervention to T1D in NOD mice. This is serological,immunohistochemical, qPCR and WB related data.
DOI: 10.6084/m9.figshare.3123388
title: Cooperative Effect of miR-141-3p and miR-145-5p in the Regulation of Targets in Clear Cell Renal Cell Carcinoma

description: <b>Background</b> Due to the poor prognosis for advanced renal cell carcinoma (RCC), there is an urgent need for new therapeutic targets and for prognostic markers to identify high risk tumors. MicroRNAs (miRNAs) are frequently dysregulated in tumors, play a crucial role during carcinogenesis and therefore might be promising new biomarkers. In previous studies, we identified miR-141-3p and miR-145-5p to be downregulated in clear cell RCC (ccRCC). Our objective was to investigate the functional association of these miRNAs, focusing on the cooperative regulation of new specific targets and their role in ccRCC progression. <b>Methods</b> The effect of miR-141-3p and miR-145-5p on cell migration was examined by overexpression in 786-O cells. New targets of both miRNAs were identified by miRWalk, validated in 786-O and ACHN cells and additionally characterized in ccRCC tissue on mRNA and protein level. <b>Results</b> In functional analysis, a tumor suppressive effect of miR-141-3p and miR-145-5p by decreasing migration and invasion of RCC cells could be shown. Furthermore, co-overexpression of the miRNAs seemed to result in an increased inhibition of cell migration. Both miRNAs were recognized as post-transcriptional regulators of the targets EAPP, HS6ST2, LOX, TGFB2 and VRK2. Additionally, they showed a cooperative effect again as demonstrated by a significantly increased inhibition of HS6ST2 and LOX expression after simultaneous overexpression of both miRNAs. In ccRCC tissue, LOX mRNA expression was strongly increased compared to normal tissue, allowing also to distinguish between non-metastatic and already metastasized primary tumors. Finally, in subsequent tissue microarray analysis LOX protein expression showed a prognostic relevance for the overall survival of ccRCC patients. <b>Conclusion</b> These results illustrate a jointly strengthening effect of the dysregulated miR-141-3p and miR-145-5p in various tumor associated processes. Focusing on the cooperative effect of miRNAs provides new opportunities for the development of therapeutic strategies and offers novel prognostic and diagnostic capabilities.
DOI: 10.6084/m9.figshare.3123367
title: An evaluation of homocysteine, C-reactive protein, lipid levels, neutrophils to lymphocyte ratio in postmenopausal osteopenic women

description: <i>Objective</i>: In the present study, the risk coefficients of serum homocysteine (hcy), lipid levels, C-reactive protein (CRP), neutrophils to lymphocyte ratio (NLR) in postmenopausal osteopenic women were determined. <i>Methods</i>: We enrolled 269 patients with postmenopausal women from Hangzhou No.1 Hospital gynecological clinic, who aged 45 to 60 years old and never received menopause hormone therapy. According to the bone mineral density determination results, subjects were divided into normal group (<i>n</i> = 128), osteopenia group (<i>n</i> = 141). Bone mineral density (BMD) was measured by dual-energy X-ray absorptiometry (DXA). Serum hcy, CRP and lipid indexes were determined by enzyme chemiluminescence immunoassay. <i>Results</i>: The odds ratios (OR) and 95% confidence intervals (CI) of those variables (menopausal age, duration of menopause, LDL, CRP, hcy and NLR) were found significant (<i>p</i> <i>Conclusion</i>: The present study shows that menopause age, duration of menopause, serum LDL, CRP, hcy and NLR levels are risk factors for postmenopausal osteopenic women, which may be used as the indicators of bone loss in postmenopausal women.
DOI: 10.6084/m9.figshare.3123367.v1
title: An evaluation of homocysteine, C-reactive protein, lipid levels, neutrophils to lymphocyte ratio in postmenopausal osteopenic women

description: <i>Objective</i>: In the present study, the risk coefficients of serum homocysteine (hcy), lipid levels, C-reactive protein (CRP), neutrophils to lymphocyte ratio (NLR) in postmenopausal osteopenic women were determined. <i>Methods</i>: We enrolled 269 patients with postmenopausal women from Hangzhou No.1 Hospital gynecological clinic, who aged 45 to 60 years old and never received menopause hormone therapy. According to the bone mineral density determination results, subjects were divided into normal group (<i>n</i> = 128), osteopenia group (<i>n</i> = 141). Bone mineral density (BMD) was measured by dual-energy X-ray absorptiometry (DXA). Serum hcy, CRP and lipid indexes were determined by enzyme chemiluminescence immunoassay. <i>Results</i>: The odds ratios (OR) and 95% confidence intervals (CI) of those variables (menopausal age, duration of menopause, LDL, CRP, hcy and NLR) were found significant (<i>p</i> <i>Conclusion</i>: The present study shows that menopause age, duration of menopause, serum LDL, CRP, hcy and NLR levels are risk factors for postmenopausal osteopenic women, which may be used as the indicators of bone loss in postmenopausal women.
DOI: 10.6084/m9.figshare.3123388.v1
title: Cooperative Effect of miR-141-3p and miR-145-5p in the Regulation of Targets in Clear Cell Renal Cell Carcinoma

description: <b>Background</b> Due to the poor prognosis for advanced renal cell carcinoma (RCC), there is an urgent need for new therapeutic targets and for prognostic markers to identify high risk tumors. MicroRNAs (miRNAs) are frequently dysregulated in tumors, play a crucial role during carcinogenesis and therefore might be promising new biomarkers. In previous studies, we identified miR-141-3p and miR-145-5p to be downregulated in clear cell RCC (ccRCC). Our objective was to investigate the functional association of these miRNAs, focusing on the cooperative regulation of new specific targets and their role in ccRCC progression. <b>Methods</b> The effect of miR-141-3p and miR-145-5p on cell migration was examined by overexpression in 786-O cells. New targets of both miRNAs were identified by miRWalk, validated in 786-O and ACHN cells and additionally characterized in ccRCC tissue on mRNA and protein level. <b>Results</b> In functional analysis, a tumor suppressive effect of miR-141-3p and miR-145-5p by decreasing migration and invasion of RCC cells could be shown. Furthermore, co-overexpression of the miRNAs seemed to result in an increased inhibition of cell migration. Both miRNAs were recognized as post-transcriptional regulators of the targets EAPP, HS6ST2, LOX, TGFB2 and VRK2. Additionally, they showed a cooperative effect again as demonstrated by a significantly increased inhibition of HS6ST2 and LOX expression after simultaneous overexpression of both miRNAs. In ccRCC tissue, LOX mRNA expression was strongly increased compared to normal tissue, allowing also to distinguish between non-metastatic and already metastasized primary tumors. Finally, in subsequent tissue microarray analysis LOX protein expression showed a prognostic relevance for the overall survival of ccRCC patients. <b>Conclusion</b> These results illustrate a jointly strengthening effect of the dysregulated miR-141-3p and miR-145-5p in various tumor associated processes. Focusing on the cooperative effect of miRNAs provides new opportunities for the development of therapeutic strategies and offers novel prognostic and diagnostic capabilities.
DOI: 10.6084/m9.figshare.3123175
title: Information, Time and the Human Mind

description: Quantum approaches to consciousness seem to explain several but not all observations in the field of mind-brain interaction. Information is introduced as a key to a wider world view since we have – according to Thomas Nagel –<i> to transcend the built-in limits of contemporary scientific orthodoxy </i>before we may <i>understand mind</i>. In the macroscopic world information is limited in contrast to the capability of our mind to work with unlimited information in mathematics. The world of mathematical concepts with unlimited information is independent of time and space and the mind is an intermediary between the macroscopic and the mathematical world. In the macroscopic world time is unidirectional while for the mind as well as in quantum physics time is bidirectional. In a given experimental system a photon carries 1 bit of information. Using a double slit gedankenexperiment it is shown that the transmission of the information from the photon to the detector takes the time span delta t = λ/c and Planck’s formula for the energy of the photon can be interpreted as Planck’s constant h multiplied by the elementary information flux (1bit) c/λ. The time span was determined by an observer in the macroscopic world. For the photon, however, time does not flow and space is shrunk to zero. For the discussion of time in quantum physical measurements these two viewpoints have to be distinguished. We may describe the photon as the elementary information unit in a world independent of time and space. The world of the photon is evidence for the existence of the world of mathematical concepts which is independent of time and space. When the information is transmitted from the world of the photon to the world of the detector it is absorbed and the loss of 1 bit information causes an increase of energy in the system. For complex information the hypothesis of an extended energy conservation law is formulated. An experimental test of the hypothetical equivalence of energy and information flux is necessary as a next step on the way which could lead to a better understanding of consciousness as well as to a quantitative theory of information.
DOI: 10.6084/m9.figshare.3123181
title: Indonesia locations and events 1500-1877 (KMZ file). Waves of destruction in the East Indies: the Wichmann catalogue of earthquakes and tsunami in the Indonesian region from 1538 to 1877

description: Translation of the catalogues into English, scanned PDFs of the original, and geographical locations of most place names found in the catalogue (as a KMZ file)
DOI: 10.6084/m9.figshare.3123148
title: Avian flight muscle masses and skeletal morphology

description: Data accompanying Wright, Steadman, and Witt 2016, Predictable evolution toward flightlessness in volant island birds, Proceedings of the National Academy of Sciences. <br>