cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q27p8zsm
title: BindingDB Entry 50033938: Discovery of a brain-penetrant S1P3-sparing direct agonist of the S1P¿? and S1P5 receptors efficacious at low oral dose.

description: Small molecule binding data for protein Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), Cytochrome P450 3A, Sphingosine 1-Phosphate Receptor 2, Sphingosine 1-Phosphate Receptor 4, Sphingosine 1-Phosphate Receptor 5, Sphingosine 1-phosphate receptor, Sphingosine 1-phosphate receptor 3, and Voltage-gated potassium channel, Uniprot O95136, O95977, P08684, P10635, P11712, P21453, P33261, Q12809, Q99500, and Q9H228
DOI: 10.7270/q2862gz8
title: BindingDB Entry 50034822: Synthesis of myo-inositol-1-phosphatase inhibitors in which the phosphate group is replaced by less polar groups

description: Small molecule binding data for protein Inositol-1(or 4)-monophosphatase 1, Uniprot P20456
DOI: 10.7270/q28p60xc
title: BindingDB Entry 50033929: Synthesis and antitumor activity of 1,2,4-triazoles having 1,4-benzodioxan fragment as a novel class of potent methionine aminopeptidase type II inhibitors.

description: Small molecule binding data for protein Methionine aminopeptidase 2, Uniprot P50579
DOI: 10.7270/q29z95ph
title: BindingDB Entry 50037484: Design, synthesis, and biological evaluation of the first selective nonpeptide AT2 receptor agonist.

description: Small molecule binding data for protein Angiotensin II receptor, Uniprot P50052
DOI: 10.7270/q2b858tf
title: BindingDB Entry 50036581: Synthesis and biological evaluation of potent, selective, hexapeptide CCK-A agonist anorectic agents.

description: Small molecule binding data for protein CCKBR and Cholecystokinin receptor, Uniprot P30551 and P30553
DOI: 10.7270/q2bc404t
title: BindingDB Entry 50035666: Diethyl 3,6-dihydro-2,4-dimethyl-2,6-methano-1,3-benzothiazocine-5,11- dicarboxylates as calcium entry antagonists: new conformationally restrained analogues of Hantzsch 1,4-dihydropyridines related to nitrendipine as probes for receptor-site conformation.

description: Small molecule binding data for protein Calcium channel (Type L), Uniprot Q13936
DOI: 10.7270/q2bz66j9
title: BindingDB Entry 50034832: Potent inhibitors of neutral endopeptidase. 2-Biphenyl- methylglutaric acid amide derivatives

description: Small molecule binding data for protein Neutral Endopeptidase (NEP), Uniprot P07861
DOI: 10.7270/q2cf9qhb
title: BindingDB Entry 50033937: Homology modeling in tandem with 3D-QSAR analyses: a computational approach to depict the agonist binding site of the human CB2 receptor.

description: Small molecule binding data for protein Cannabinoid receptor 1 and Cannabinoid receptor 2, Uniprot P21554 and P34972
DOI: 10.7270/q2cz37n7
title: BindingDB Entry 50034821: The antitumor activity of novel pyrazoloquinoline derivatives

description: Small molecule binding data for protein DNA topoisomerase II, Uniprot P11388 and Q02880
DOI: 10.7270/q2df6rm8
title: BindingDB Entry 50033928: Metronidazole acid acyl sulfonamide: a novel class of anticancer agents and potential EGFR tyrosine kinase inhibitors.

description: Small molecule binding data for protein Epidermal growth factor receptor and Epidermal growth factor receptor and ErbB2 (HER1 and HER2), Uniprot P00533 and P04626
DOI: 10.7270/q2fq9xdv
title: BindingDB Entry 50037483: Improved structure-activity relationship analysis of HIV-1 protease inhibitors using interaction kinetic data.

description: Small molecule binding data for protein Human immunodeficiency virus type 1 protease
DOI: 10.7270/q2g161hq
title: BindingDB Entry 50036580: Synthesis and pharmacological evaluation of N-(2,5-disubstituted phenyl)-N'-(3-substituted phenyl)-N'-methylguanidines as N-methyl-D-aspartate receptor ion-channel blockers.

description: Small molecule binding data for protein Sigma, Uniprot Q99720
DOI: 10.7270/q2g44qw6
title: BindingDB Entry 50035665: Folate analogues as inhibitors of thymidylate synthase.

description: Small molecule binding data for protein Thymidylate Synthase (TS) and Thymidylate synthase, Uniprot P00469, P04818, and P07607
DOI: 10.7270/q2gq6z76
title: BindingDB Entry 50034831: Reduced amide bond neurotensin 813 mimetics with potent in vivo activity

description: Small molecule binding data for protein Neurotensin receptor 1, Uniprot O88319
DOI: 10.7270/q2h70g65
title: BindingDB Entry 50033936: Synthesis and evaluation of quinazolin-4-ones as hypoxia-inducible factor-1a inhibitors.

description: Small molecule binding data for protein Hypoxia-inducible factor 1-alpha, Uniprot Q16665
DOI: 10.7270/q2jh3mzw
title: BindingDB Entry 50037490: Synthesis and structure-activity relationships of 1-aralkyl-4-benzylpiperidine and 1-aralkyl-4-benzylpiperazine derivatives as potent sigma ligands.

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 1A, Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor, and Sigma, Uniprot P08908, P61169, and Q99720
DOI: 10.7270/q2kh0p44
title: BindingDB Entry 50037482: Fluorinated phenylcyclopropylamines. 2. Effects of aromatic ring substitution and of absolute configuration on inhibition of microbial tyramine oxidase.

description: Small molecule binding data for protein Amine oxidase [flavin-containing] A and Amine oxidase [flavin-containing] B, Uniprot P21397 and P27338
DOI: 10.7270/q2kp82td
title: BindingDB Entry 50036579: New generation dopaminergic agents. 1. Discovery of a novel scaffold which embraces the D2 agonist pharmacophore. Structure-activity relationships of a series of 2-(aminomethyl)chromans.

description: Small molecule binding data for protein Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor, Dopamine receptor, Dopamine receptor D2L/neurotensin receptor NTS1, Dopamine receptors; D2 & D4, and Serotonin (5-HT) receptor, Uniprot P14416, P19327, P21917, P35462, and P61169
DOI: 10.7270/q2kw5gmm
title: BindingDB Entry 50035664: Thienothiopyran-2-sulfonamides: a novel class of water-soluble carbonic anhydrase inhibitors.

description: Small molecule binding data for protein Carbonic anhydrase 2, Uniprot P00918
DOI: 10.7270/q2mw2hj9
title: BindingDB Entry 50033934: Thailandepsins: bacterial products with potent histone deacetylase inhibitory activities and broad-spectrum antiproliferative activities.

description: Small molecule binding data for protein Histone deacetylase, Histone deacetylase 3/Nuclear receptor corepressor 2, Histone deacetylase 4, Histone deacetylase 7 (HDAC7), and Histone deacetylase 8, Uniprot A0A024QZ26, O15379, P56524, Q8WUI4, Q9BY41, Q9UBN7, Q9UKV0, and Q9Y618
DOI: 10.7270/q2p84cpm
title: BindingDB Entry 50037489: Propidium-based polyamine ligands as potent inhibitors of acetylcholinesterase and acetylcholinesterase-induced amyloid-beta aggregation.

description: Small molecule binding data for protein Acetylcholinesterase, Butyrylcholinesterase (BChE), and Cholinesterase, Uniprot P06276, P22303, and Q9N1N9
DOI: 10.7270/q2qf8th9
title: BindingDB Entry 50036578: Neuronal nicotinic acetylcholine receptors as targets for drug discovery.

description: Small molecule binding data for protein Acetylcholine receptor protein alpha/beta/delta/gamma chain, Neuronal acetylcholine receptor, Neuronal acetylcholine receptor protein alpha-3/beta-4 subunit, Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit, and Neuronal acetylcholine receptor protein alpha-7 subunit, Uniprot P02710, P02712, P02714, P02718, P09483, P12390, P17787, P30926, P32297, P36544, P43681, and Q05941
DOI: 10.7270/q2qn67bb
title: BindingDB Entry 50035663: Hydroxamic acid inhibitors of 5-lipoxygenase.

description: Small molecule binding data for protein Arachidonate 5-lipoxygenase, Uniprot P12527
DOI: 10.7270/q2r78fp7
title: BindingDB Entry 50034827: Synthesis and pharmacological activity of a macrocyclic benzamide

description: Small molecule binding data for protein Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor, Serotonin (5-HT) receptor, and Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor, Uniprot P35563, P61169, Q62758, and Q9JJ16
DOI: 10.7270/q2rn387k
title: BindingDB Entry 50033933: Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder.

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 1A, Cytochrome P450 1A, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), Cytochrome P450 3A, NPY5R, Neuropeptide Y receptor type 1, Neuropeptide Y receptor type 2, Neuropeptide Y receptor type 5 ( NPY Y5), PPYR1, Serotonin and norepinephrine transporters (SERT/NET), Serotonin receptor (2b and 2c), and Voltage-gated potassium channel, Uniprot P05177, P08684, P08908, P10635, P11712, P25929, P31645, P33261, P41595, P49146, P50391, Q12809, Q15761, and Q63634
DOI: 10.7270/q2s75gtm
title: BindingDB Entry 50034817: Structure activity relationships of non-peptide bradykinin B2 receptor antagonists

description: Small molecule binding data for protein Bradykinin B2 receptor and Muscarinic acetylcholine receptor, Uniprot O70526, P08482, P08483, P08485, P08911, P10980, and P30411
DOI: 10.7270/q2t154db
title: BindingDB Entry 50037488: 5-substituted, 6-substituted, and unsubstituted 3-heteroaromatic pyridine analogues of nicotine as selective inhibitors of cytochrome P-450 2A6.

description: Small molecule binding data for protein Cytochrome P450 2A6, Cytochrome P450 2B6, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), Cytochrome P450 2E1, and Cytochrome P450 3A, Uniprot P05181, P08684, P10635, P11509, P11712, P20813, and P33261
DOI: 10.7270/q2v69k71
title: BindingDB Entry 50036577: Viracept (nelfinavir mesylate, AG1343): a potent, orally bioavailable inhibitor of HIV-1 protease.

description: Small molecule binding data for protein Human immunodeficiency virus type 1 protease
DOI: 10.7270/q2v988ps
title: BindingDB Entry 50035662: alpha-Methylproline-containing renin inhibitory peptides: in vivo evaluation in an anesthetized, ganglion-blocked, hog renin infused rat model.

description: Small molecule binding data for protein Renin, Uniprot P00797
DOI: 10.7270/q2w096dz
title: BindingDB Entry 50034826: Inhibition of prolidase by phosphoenolpyruvate is biphasic. avoidance of endogenous-metabolite inactivation by cooperativity within an enzyme dimer

description: Small molecule binding data for protein Xaa-Pro dipeptidase, Uniprot P12955
DOI: 10.7270/q2wd40zw
title: BindingDB Entry 50033932: High affinity sialoside ligands of myelin associated glycoprotein.

description: Small molecule binding data for protein Myelin-associated glycoprotein, Uniprot P20916
DOI: 10.7270/q2xp75q1
title: BindingDB Entry 50037487: Control of hepatitis C: a medicinal chemistry perspective.

description: Small molecule binding data for protein Genome polyprotein and Hepatitis C virus serine protease, NS3/NS4A, Uniprot P26664 and Q4JMH3 A3EZI9
DOI: 10.7270/q2zp46vd
title: BindingDB Entry 50037479: Evaluation of lactam-bridged neurotensin analogues adjusting psi(Pro10) close to the experimentally derived bioactive conformation of NT(8-13).

description: Small molecule binding data for protein Dopamine receptor D2L/neurotensin receptor NTS1, Uniprot P30989
DOI: 10.7270/q2057g9t
title: BindingDB Entry 50033940: 3D QSAR and docking study of flavone derivatives as potent inhibitors of influenza H1N1 virus neuraminidase.

description: Small molecule binding data for protein Neuraminidase A, Uniprot P03468
DOI: 10.7270/q2125th5
title: BindingDB Entry 50038384: [4-(Phenoxy)pyridin-3-yl]methylamines: a new class of selective noradrenaline reuptake inhibitors.

description: Small molecule binding data for protein Cytochrome P450 1A, Cytochrome P450 2D6 (2D6), Cytochrome P450 3A, Serotonin and norepinephrine transporters (SERT/NET), Sodium-dependent dopamine transporter, Sodium-dependent noradrenaline transporter, and Voltage-gated potassium channel, Uniprot P05177, P08684, P10635, P23975, P31645, Q01959, and Q12809
DOI: 10.7270/q21g0n2h
title: BindingDB Entry 50037494: The next generation of phosphodiesterase inhibitors: structural clues to ligand and substrate selectivity of phosphodiesterases.

description: Small molecule binding data for protein Phosphodiesterase 1, Phosphodiesterase 11A (PDE11A), Phosphodiesterase 3, Phosphodiesterase 4, Phosphodiesterase 6, Phosphodiesterase 7, Phosphodiesterase 9A, cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, cGMP-dependent 3',5'-cyclic phosphodiesterase, and cGMP-specific 3',5'-cyclic phosphodiesterase, Uniprot O00408, O43924, O76074, O76083, P16499, P18545, P27815, P35913, P51160, P54750, Q01064, Q07343, Q08493, Q08499, Q13370, Q13946, Q13956, Q14123, Q14432, Q9HCR9, Q9NP56, and Q9Y233
DOI: 10.7270/q21v5fj0
title: BindingDB Entry 50035683: Quantitative structure-activity relationship of triazine-antifolate inhibition of Leishmania dihydrofolate reductase and cell growth.

description: Small molecule binding data for protein Thymidylate synthase (TS), Uniprot P07382
DOI: 10.7270/q22r3sbz
title: BindingDB Entry 50036583: Synthesis, structure, dopamine transporter affinity, and dopamine uptake inhibition of 6-alkyl-3-benzyl-2-[(methoxycarbonyl)methyl]tropane derivatives.

description: Small molecule binding data for protein Dopamine Transporter (DAT), Uniprot P23977
DOI: 10.7270/q23j3dgf
title: BindingDB Entry 50034834: Novel benzimidazole-4-carboxylic acid derivatives as potent and selective 5-HT3 receptor ligands

description: Small molecule binding data for protein HTR4 and Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor, Uniprot P35563, Q62758, and Q9JJ16
DOI: 10.7270/q23x8717
title: BindingDB Entry 50033939: Inhibition of COX-1 activity and COX-2 expression by 3-(4'-geranyloxy-3'-methoxyphenyl)-2-trans propenoic acid and its semi-synthetic derivatives.

description: Small molecule binding data for protein Prostaglandin G/H synthase (cyclooxygenase), Uniprot P05979
DOI: 10.7270/q24t6k7k
title: BindingDB Entry 50038383: Synthesis of a potent and selective (18)F-labeled delta-opioid receptor antagonist derived from the Dmt-Tic pharmacophore for positron emission tomography imaging.

description: Small molecule binding data for protein Delta-type opioid receptor, Nociceptin/mu opioid receptor, Opioid receptors; mu & delta, and mu/kappa opioid receptor, Uniprot P32300, P33533, P33535, and P97266
DOI: 10.7270/q2571cst
title: BindingDB Entry 50037493: 4-(2-[2-(2(R)-methylpyrrolidin-1-yl)ethyl]benzofuran-5-yl)benzonitrile and related 2-aminoethylbenzofuran H3 receptor antagonists potently enhance cognition and attention.

description: Small molecule binding data for protein Histamine H3 receptor and Histamine receptor (H3), Uniprot Q9QYN8 and Q9Y5N1
DOI: 10.7270/q25m668q
title: BindingDB Entry 50035682: Synthesis and 5-lipoxygenase inhibitory activity of 5-hydroperoxy-6,8,11,14-eicosatetraenoic acid analogues.

description: Small molecule binding data for protein Arachidonate 5-lipoxygenase, Uniprot P12527
DOI: 10.7270/q26q1xns
title: BindingDB Entry 50033946: RGD mimetics containing phthalimidine fragment as novel ligands of fibrinogen receptor.

description: Small molecule binding data for protein Integrin alpha-2/beta-3, Uniprot P05106 and P17301
DOI: 10.7270/q279455q
title: BindingDB Entry 50034833: 2-cyanopyrrolidides as potent, stable inhibitors of dipeptidyl peptidase IV

description: Small molecule binding data for protein Dipeptidyl peptidase II and dipeptidyl peptidase IV (DPP2 and DPP4), Uniprot P27487
DOI: 10.7270/q28k79zw
title: BindingDB Entry 50038382: Novel 2,3-dihydro-1,4-benzoxazines as potent and orally bioavailable inhibitors of tumor-driven angiogenesis.

description: Small molecule binding data for protein Hepatocyte growth factor receptor, SRC, Vascular endothelial growth factor receptor 2, and Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2), Uniprot P06239, P08581, P35968, and Q02763
DOI: 10.7270/q29024j0
title: BindingDB Entry 50037492: Inhibition of nucleoside transport proteins by C8-alkylamine-substituted purines.

description: Small molecule binding data for protein Equilibrative Nucleoside Transporter 1 (ENT1), Uniprot Q99808
DOI: 10.7270/q29c6z02
title: BindingDB Entry 50035681: Synthesis and structure-activity relationships of potent new angiotensin converting enzyme inhibitors containing saturated bicyclic amino acids.

description: Small molecule binding data for protein Angiotensin-converting enzyme, Uniprot P47820
DOI: 10.7270/q2bg2pdz
title: BindingDB Entry 50033945: Targeting hypoxic tumor cell viability with carbohydrate-based carbonic anhydrase IX and XII inhibitors.

description: Small molecule binding data for protein Carbonic anhydrase, Carbonic anhydrase 12, Carbonic anhydrase 2, and Carbonic anhydrase 9, Uniprot O43570, P00915, P00918, and Q16790
DOI: 10.7270/q2cr5v36
title: BindingDB Entry 50037499: Synthesis and structure-activity relationships of novel selective factor Xa inhibitors with a tetrahydroisoquinoline ring.

description: Small molecule binding data for protein Coagulation factor X/antithrombin III, Plasminogen, Prothrombin, and Trypsin II, Uniprot P00734, P00742, P00747, P07477, and P07478
DOI: 10.7270/q2dr2w81
title: BindingDB Entry 50037491: Design and NMR characterization of active analogues of compstatin containing non-natural amino acids.

description: Small molecule binding data for protein Complement C3, Uniprot P01024
DOI: 10.7270/q2f190ds
title: BindingDB Entry 50036588: Probes for narcotic receptor mediated phenomena. 23. Synthesis, opioid receptor binding, and bioassay of the highly selective delta agonist (+)-4-[(alpha R)-alpha-((2S,5R)-4-Allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]- N,N-diethylbenzamide (SNC 80) and related novel nonpeptide delta opioid r

description: Small molecule binding data for protein Delta-type opioid receptor, Nociceptin/mu opioid receptor, Opioid receptors; mu & delta, and mu/kappa opioid receptor, Uniprot P32300, P33533, P33535, and P97266
DOI: 10.7270/q2f47pqc
title: BindingDB Entry 50035680: Inhibition of the mammalian beta-lactamase renal dipeptidase (dehydropeptidase-I) by (Z)-2-(acylamino)-3-substituted-propenoic acids.

description: Small molecule binding data for protein Renal dipeptidase, Uniprot P22412
DOI: 10.7270/q2g73f4p
title: BindingDB Entry 50033944: Dihydroquinazolines as a novel class of Trypanosoma brucei trypanothione reductase inhibitors: discovery, synthesis, and characterization of their binding mode by protein crystallography.

description: Small molecule binding data for protein Glutathione reductase (GR), Trypanothione Reductase (TryR), and Trypanothione reductase, Uniprot P00390, P28593, and P39051
DOI: 10.7270/q2j38tfd
title: BindingDB Entry 50038380: 1,3-Dipropyl-8-(1-phenylacetamide-1H-pyrazol-3-yl)-xanthine derivatives as highly potent and selective human A(2B) adenosine receptor antagonists.

description: Small molecule binding data for protein Adenosine receptor A1, Adenosine receptor A2a, Adenosine receptor A2b, and Adenosine receptor A3, Uniprot P0DMS8, P29274, P29275, and P30542
DOI: 10.7270/q2js9r3c
title: BindingDB Entry 50036587: Structural requirements for binding of anandamide-type compounds to the brain cannabinoid receptor.

description: Small molecule binding data for protein Cannabinoid receptor and Cannabinoid receptor 1, Uniprot P20272 and P21554
DOI: 10.7270/q2jw8fg7
title: BindingDB Entry 50035679: Synthesis, structure, and biological activity of certain 2-deoxy-beta-D-ribo-hexopyranosyl nucleosides and nucleotides.

description: Small molecule binding data for protein Adenosine deaminase, Uniprot P56658
DOI: 10.7270/q2kh0nv4
title: BindingDB Entry 50034838: Mechanism-based inactivation of E. coli -glutamylcysteine synthetase by phosphinic acid- and sulfoximine-based transition-state analogues

description: Small molecule binding data for protein Gamma-glutamylcysteine synthetase, Uniprot P48506
DOI: 10.7270/q2m045tj
title: BindingDB Entry 50033943: Discovery and kinetic evaluation of 6-substituted 4-benzylthio-1,3,5-triazin-2(1H)-ones as inhibitors of cathepsin B.

description: Small molecule binding data for protein Cathepsin (B and K), Uniprot P07858
DOI: 10.7270/q2mg7pzh
title: BindingDB Entry 50034829: Structure-activity and biophysical studies of the C-terminal hexapeptide of endothelin

description: Small molecule binding data for protein EDNRA and EDNRB, Uniprot P21451 and P25101
DOI: 10.7270/q2n87bj7
title: BindingDB Entry 50037497: Varenicline: an alpha4beta2 nicotinic receptor partial agonist for smoking cessation.

description: Small molecule binding data for protein Acetylcholine receptor protein alpha/beta/delta/gamma chain and Neuronal acetylcholine receptor, Uniprot P02710, P02712, P02714, P02718, and Q05941
DOI: 10.7270/q2pg1sdx
title: BindingDB Entry 50036586: Structure-based design of new constrained cyclic agonists of the cholecystokinin CCK-B receptor.

description: Small molecule binding data for protein CCKBR, Cholecystokinin A receptor, and Cholecystokinin receptor, Uniprot P30553, P32239, and Q63931
DOI: 10.7270/q2pn967d
title: BindingDB Entry 50035677: N6-phenyladenosines: pronounced effect of phenyl substituents on affinity for A2 adenosine receptors.

description: Small molecule binding data for protein ADORA1, Uniprot P49892
DOI: 10.7270/q2q81dkv
title: BindingDB Entry 50034837: Solid phase synthesis of phosphinic acid endothelin converting enzyme inhibitors

description: Small molecule binding data for protein Endothelin-converting enzyme 1 (ECE1) and Neprilysin, Uniprot P08473 and P42892
DOI: 10.7270/q2qn6753
title: BindingDB Entry 50033942: Pyrrolidin-3-yl-N-methylbenzamides as potent histamine 3 receptor antagonists.

description: Small molecule binding data for protein Histamine receptor (H3) and Voltage-gated potassium channel, Uniprot Q12809 and Q9Y5N1
DOI: 10.7270/q2s1838z
title: BindingDB Entry 50037496: Synthesis and biological evaluation of benzodioxanylpiperazine derivatives as potent serotonin 5-HT(1A) antagonists: the discovery of Lecozotan.

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 1A, Uniprot P08908
DOI: 10.7270/q2t72j36
title: BindingDB Entry 50036585: New esters of 4-amino-5-chloro-2-methoxybenzoic acid as potent agonists and antagonists for 5-HT4 receptors.

description: Small molecule binding data for protein HTR4 and Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor, Uniprot O70528, P35563, Q62758, and Q9JJ16
DOI: 10.7270/q2td9xxw
title: BindingDB Entry 50035676: Hexahydro-1H-1-pyrindines from acid rearrangement of 9-alkylidene-5-(m-methoxyphenyl)-2-methylmorphans. A new structural type of narcotic antagonists.

description: Small molecule binding data for protein Nociceptin/mu opioid receptor, Uniprot P33535
DOI: 10.7270/q2v1259k
title: BindingDB Entry 50034836: Synthesis of N-kojic-amino acid and N-kojic-amino acid-kojiate and their tyrosinase inhibitory activity

description: Small molecule binding data for protein Tyrosinase, Uniprot P14679
DOI: 10.7270/q2vd6zt4
title: BindingDB Entry 50033941: Synthesis and biological evaluation of 4-piperidinecarboxylate and 4-piperidinecyanide derivatives for T-type calcium channel blockers.

description: Small molecule binding data for protein Voltage-gated T-type calcium channel and Voltage-gated potassium channel, Uniprot O43497 and Q12809
DOI: 10.7270/q2w95b2q
title: BindingDB Entry 50038385: Potent antagonists of the CCR2b receptor. Part 3: SAR of the (R)-3-aminopyrrolidine series.

description: Small molecule binding data for protein C-C chemokine receptor type 1 and C-C chemokine receptor type 2, Uniprot O95950, P32246, and P41597
DOI: 10.7270/q2ws8v00
title: BindingDB Entry 50037495: Structure-based virtual screening for plant-based ERbeta-selective ligands as potential preventative therapy against age-related neurodegenerative diseases.

description: Small molecule binding data for protein Estradiol receptor alpha (ERα) and Estradiol receptor beta (ERβ), Uniprot P03372 and Q92731
DOI: 10.7270/q2z038th
title: BindingDB Entry 50036584: 2-(1-Naphthyloxy)ethylamines with enhanced affinity for human 5-HT1D beta (h5-HT1B) serotonin receptors.

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine receptor 1D, Uniprot P28221 and P28222