cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.14278/rodare.4121
title: Data publication: Optimizations on Graph-Level for Domain Specific Computations in Julia and Application to QED

description: Experiment run and plotting code, and produced data for the accompanying paper.
DOI: 10.15468/dl.y8ky7s
title: Occurrence Download

description: A dataset containing 6838509 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Galaxias occidentalis, Bos taurus, Chenonetta jubata, Nannoperca vittata, Bostockia porosa, Macropus fuliginosus, Canis lupus, Pseudogobius olorum, Tandanus bostocki, Ranoidea cyclorhynchus, Gymnorhina tibicen, Eolophus roseicapilla, Phaps chalcoptera, Chordata, Malacorhynchus membranaceus, Threskiornis spinicollis)",
 "StateProvince is Western Australia",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 "BasisOfRecord is one of (Occurrence evidence, Material sample, Human Observation, Specimen, Machine Observation, Observation)"
 ]
}

 The dataset includes 6838509 records from 168 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0032656-251025141854904/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.34740/kaggle/dsv/13728196
title: Peer-to-Peer Boliviano (BOB) Exchange Data
DOI: 10.14278/rodare.4118
title: Data publication: Solutal Marangoni Convection at Growing Oxygen Bubbles during Water Electrolysis

description: Raw data
DOI: 10.14278/rodare.4117
title: Data publication: Solutal Marangoni Convection at Growing Oxygen Bubbles during Water Electrolysis

description: Raw data
DOI: 10.6084/m9.figshare.30617162
title: Supplementary Material for: High-Frequency Ultrasound Quantification of Endophytic Growth Pattern: A Potential Imaging Indicator for Grading Cutaneous Squamous Cell Carcinoma Differentiation

description: Background: Cutaneous squamous cell carcinoma (cSCC) is the second most common type of skin cancer. While most tumors have a positive prognosis, poorly-differentiated tumors increase the risk of negative outcomes. Few studies are available on non-invasive methods to determine the level of differentiation of cSCC before surgery. 
Objective: To determine the degree of differentiation of cSCC using high-frequency ultrasound (HFUS).
Methods: This study included 117 lesions from 117 patients, of which 68 were well-differentiated cSCC, 30 were moderately-differentiated and 19 were poorly-differentiated. We analyzed the clinical, appearance, histopathological and HFUS characteristics of cSCC. The thickness characteristics measured by HFUS included the overall thickness of the tumor, the thickness of the tumor's endophytic part , and the proportion of endophytic thickness to the overall thickness. 
Results: The three groups did not show significant differences in their clinical and appearance features (all P &gt; 0.017). However, on HFUS, the lesion total thickness, endophytic proportion and surface keratinization were the significant features for identifying poorly-differentiated cSCC. While a single indicator is not as effective as the combination of all three (all P &gt; 0.05), the diagnostic accuracy of any two or all three indicators together did not show significant differences (P &lt; 0.05).
Conclusions: HFUS can reveal internal morphological details of cSCC lesions, identifying poorly-differentiated cSCC by analyzing total lesion thickness, endophytic proportion, and surface hyperkeratinization. Any two of these features can be as effective as using all three to diagnose poorly-differentiated cSCC.
DOI: 10.6084/m9.figshare.30617162.v1
title: Supplementary Material for: High-Frequency Ultrasound Quantification of Endophytic Growth Pattern: A Potential Imaging Indicator for Grading Cutaneous Squamous Cell Carcinoma Differentiation

description: Background: Cutaneous squamous cell carcinoma (cSCC) is the second most common type of skin cancer. While most tumors have a positive prognosis, poorly-differentiated tumors increase the risk of negative outcomes. Few studies are available on non-invasive methods to determine the level of differentiation of cSCC before surgery. 
Objective: To determine the degree of differentiation of cSCC using high-frequency ultrasound (HFUS).
Methods: This study included 117 lesions from 117 patients, of which 68 were well-differentiated cSCC, 30 were moderately-differentiated and 19 were poorly-differentiated. We analyzed the clinical, appearance, histopathological and HFUS characteristics of cSCC. The thickness characteristics measured by HFUS included the overall thickness of the tumor, the thickness of the tumor's endophytic part , and the proportion of endophytic thickness to the overall thickness. 
Results: The three groups did not show significant differences in their clinical and appearance features (all P &gt; 0.017). However, on HFUS, the lesion total thickness, endophytic proportion and surface keratinization were the significant features for identifying poorly-differentiated cSCC. While a single indicator is not as effective as the combination of all three (all P &gt; 0.05), the diagnostic accuracy of any two or all three indicators together did not show significant differences (P &lt; 0.05).
Conclusions: HFUS can reveal internal morphological details of cSCC lesions, identifying poorly-differentiated cSCC by analyzing total lesion thickness, endophytic proportion, and surface hyperkeratinization. Any two of these features can be as effective as using all three to diagnose poorly-differentiated cSCC.
DOI: 10.6084/m9.figshare.30617165
title: Supplementary Material for: Traditional Chinese Medicine in the Management of Colorectal Cancer Liver Metastasis: Mechanisms, Challenges, and Perspectives

description: Background: Colorectal cancer (CRC) is a leading global malignancy, with the liver being the primary site of distant metastasis. Colorectal cancer liver metastasis (CRLM) is the predominant cause of mortality in CRC patients. Emerging evidence underscores the complexity of CRLM mechanisms, where the tumor microenvironment (TME) plays a central role in driving metastasis and fostering treatment resistance. Current Western medical strategies (chemotherapy, targeted therapy, immunotherapy, surgery) offer limited disease control, often accompanied by adverse effects, and lack specific pharmacological interventions targeting CRLM effectively. Summary: This review systematically evaluates the potential of Traditional Chinese Medicine (TCM) – guided by holistic and syndrome differentiation principles – as a therapeutic approach for CRLM. By analyzing literature from PubMed, Web of Science, Embase, CNKI, and Wanfang databases, we find that TCM interventions (formulas, herb pairs, phytochemicals) exert therapeutic effects by modulating the TME through multiple mechanisms. These include inhibiting extracellular matrix (ECM) remodeling, suppressing hypoxia-induced angiogenesis, and reversing immune evasion. Key Message: TCM exhibits unique multi-component, multi-target, and multi-pathway advantages against CRLM, presenting a promising complementary strategy. Future high-quality research, particularly well-designed clinical trials, is essential to validate efficacy, understand mechanisms further, and translate the potential of TCM into clinically meaningful benefits for CRLM patients.
DOI: 10.6084/m9.figshare.30617165.v1
title: Supplementary Material for: Traditional Chinese Medicine in the Management of Colorectal Cancer Liver Metastasis: Mechanisms, Challenges, and Perspectives

description: Background: Colorectal cancer (CRC) is a leading global malignancy, with the liver being the primary site of distant metastasis. Colorectal cancer liver metastasis (CRLM) is the predominant cause of mortality in CRC patients. Emerging evidence underscores the complexity of CRLM mechanisms, where the tumor microenvironment (TME) plays a central role in driving metastasis and fostering treatment resistance. Current Western medical strategies (chemotherapy, targeted therapy, immunotherapy, surgery) offer limited disease control, often accompanied by adverse effects, and lack specific pharmacological interventions targeting CRLM effectively. Summary: This review systematically evaluates the potential of Traditional Chinese Medicine (TCM) – guided by holistic and syndrome differentiation principles – as a therapeutic approach for CRLM. By analyzing literature from PubMed, Web of Science, Embase, CNKI, and Wanfang databases, we find that TCM interventions (formulas, herb pairs, phytochemicals) exert therapeutic effects by modulating the TME through multiple mechanisms. These include inhibiting extracellular matrix (ECM) remodeling, suppressing hypoxia-induced angiogenesis, and reversing immune evasion. Key Message: TCM exhibits unique multi-component, multi-target, and multi-pathway advantages against CRLM, presenting a promising complementary strategy. Future high-quality research, particularly well-designed clinical trials, is essential to validate efficacy, understand mechanisms further, and translate the potential of TCM into clinically meaningful benefits for CRLM patients.
DOI: 10.6084/m9.figshare.30617168
title: Supplementary Material for: Chronic cutaneous lupus erythematosus presenting as acne scars: A case report

description: Chronic cutaneous lupus erythematosus (CCLE) lesions often present as typical forms ; erythematous patches and infiltrated coin-shaped plaques that are pink to violaceous in color. However, more than 20 other rare clinical presentations have been described in the literature. One of these rare presentations is acneiform lesions, perhaps one of the most important to recognize because they can readily be mistaken for acne vulgaris, which is one of the most common dermatological conditions. 
We present a rare case of acneiform CCLE that was misdiagnosed and treated as acne vulgaris for over 20 years, ultimately presenting to our clinic with acne scars.
DOI: 10.6084/m9.figshare.30617168.v1
title: Supplementary Material for: Chronic cutaneous lupus erythematosus presenting as acne scars: A case report

description: Chronic cutaneous lupus erythematosus (CCLE) lesions often present as typical forms ; erythematous patches and infiltrated coin-shaped plaques that are pink to violaceous in color. However, more than 20 other rare clinical presentations have been described in the literature. One of these rare presentations is acneiform lesions, perhaps one of the most important to recognize because they can readily be mistaken for acne vulgaris, which is one of the most common dermatological conditions. 
We present a rare case of acneiform CCLE that was misdiagnosed and treated as acne vulgaris for over 20 years, ultimately presenting to our clinic with acne scars.
DOI: 10.14278/rodare.4116
title: Data publication: Lagrangian tracking reveals competing influences of clustering and turbulence on the rise velocity of bubble swarms

description: This data publication contains the data to reproduce the Figures for the paper "Lagrangian tracking reveals competing influences of clustering and turbulence on the rise velocity of bubble swarms".
DOI: 10.6084/m9.figshare.30617171
title: Supplementary Material for: Chloroquine enhances MAVS-mediated cytokine induction and alters mitochondrial morphology

description: Introduction: Chloroquine (CQ), a well-known antimalarial agent, has been proposed as a potential antiviral compound due to its ability to interfere with multiple cellular pathways critical for viral replication. Although CQ exhibits broad-spectrum antiviral activity, its effect on host innate immune responses remains incompletely understood. The timing of CQ administration, whether before or after infection, may lead to different immunological outcomes. Therefore, the immunomodulatory effects of CQ should be carefully evaluated before antiviral therapy. Methods: To investigate the immunomodulatory role of CQ (50 M), we used immunofluorescence staining, western blotting, and reporter assays to evaluate innate immune activation in A549 cells. We established a doxycycline-inducible system to activate MAVS-mediated signaling without viral infection. Plaque assays and antiviral tests were performed to measure viral replication, while cytokine array and RT-qPCR were used to quantify cytokine production. Mitochondrial morphology was assessed using immunofluorescence microscopy. Results: CQ enhanced innate immune responses triggered by dengue virus infection and Poly(I:C) stimulation. This enhancement was associated with the activation of the mitochondrial antiviral signaling protein (MAVS) and its upstream receptors, including retinoic acid-inducible gene I and melanoma differentiation-associated protein 5. CQ strengthened MAVS-dependent antiviral signaling and increased IL-6 induction more than 13-fold. Alterations in mitochondrial morphology may contribute to this immunostimulatory effect. Conclusion: CQ promotes MAVS-mediated antiviral and inflammatory cytokine responses, potentially through its effect on mitochondrial dynamics. These findings indicate that while CQ may enhance antiviral defense, its immune-stimulating properties should be carefully evaluated prior to its use as an antiviral agent in treating RNA virus infections.
DOI: 10.6084/m9.figshare.30617171.v1
title: Supplementary Material for: Chloroquine enhances MAVS-mediated cytokine induction and alters mitochondrial morphology

description: Introduction: Chloroquine (CQ), a well-known antimalarial agent, has been proposed as a potential antiviral compound due to its ability to interfere with multiple cellular pathways critical for viral replication. Although CQ exhibits broad-spectrum antiviral activity, its effect on host innate immune responses remains incompletely understood. The timing of CQ administration, whether before or after infection, may lead to different immunological outcomes. Therefore, the immunomodulatory effects of CQ should be carefully evaluated before antiviral therapy. Methods: To investigate the immunomodulatory role of CQ (50 M), we used immunofluorescence staining, western blotting, and reporter assays to evaluate innate immune activation in A549 cells. We established a doxycycline-inducible system to activate MAVS-mediated signaling without viral infection. Plaque assays and antiviral tests were performed to measure viral replication, while cytokine array and RT-qPCR were used to quantify cytokine production. Mitochondrial morphology was assessed using immunofluorescence microscopy. Results: CQ enhanced innate immune responses triggered by dengue virus infection and Poly(I:C) stimulation. This enhancement was associated with the activation of the mitochondrial antiviral signaling protein (MAVS) and its upstream receptors, including retinoic acid-inducible gene I and melanoma differentiation-associated protein 5. CQ strengthened MAVS-dependent antiviral signaling and increased IL-6 induction more than 13-fold. Alterations in mitochondrial morphology may contribute to this immunostimulatory effect. Conclusion: CQ promotes MAVS-mediated antiviral and inflammatory cytokine responses, potentially through its effect on mitochondrial dynamics. These findings indicate that while CQ may enhance antiviral defense, its immune-stimulating properties should be carefully evaluated prior to its use as an antiviral agent in treating RNA virus infections.
DOI: 10.14278/rodare.4115
title: Data publication: Lagrangian tracking reveals competing influences of clustering and turbulence on the rise velocity of bubble swarms

description: This data publication contains the data to reproduce the Figures for the paper "Lagrangian tracking reveals competing influences of clustering and turbulence on the rise velocity of bubble swarms".
DOI: 10.6084/m9.figshare.30617174
title: Supplementary Material for: Recurrent Vision Fluctuations and Orbital Signs Unmasking T-Cell Lymphoma: A Case Report

description: Introduction
Orbital T-cell lymphoma is a rare and diagnostically challenging malignancy that can closely mimic inflammatory conditions such as Tolosa-Hunt Syndrome (THS), particularly due to overlapping clinical and radiological features.
 
Case Presentation
We report a 21-year-old male who initially fulfilled the ICHD-3 criteria for THS, demonstrating unilateral painful ophthalmoplegia and transient steroid responsiveness. However, recurrence of symptoms and subsequent histopathological evaluation confirmed the presence of extranodal orbital T-cell lymphoma. This case underscores the critical importance of maintaining a high index of suspicion for malignancy in steroid-responsive orbital syndromes, especially when atypical features or relapses occur. Early biopsy and multidisciplinary coordination enabled timely initiation of CHOEP chemotherapy, leading to slight clinical improvement. This report adds to the growing body of literature emphasizing the masquerade potential of lymphoid malignancies in orbital inflammation.
Conclusion:
Orbital T-cell lymphoma can mimic benign inflammatory conditions such as orbital cellulitis. Prompt biopsy and multidisciplinary evaluation are crucial for accurate diagnosis and timely initiation of appropriate treatment.
DOI: 10.6084/m9.figshare.30617174.v1
title: Supplementary Material for: Recurrent Vision Fluctuations and Orbital Signs Unmasking T-Cell Lymphoma: A Case Report

description: Introduction
Orbital T-cell lymphoma is a rare and diagnostically challenging malignancy that can closely mimic inflammatory conditions such as Tolosa-Hunt Syndrome (THS), particularly due to overlapping clinical and radiological features.
 
Case Presentation
We report a 21-year-old male who initially fulfilled the ICHD-3 criteria for THS, demonstrating unilateral painful ophthalmoplegia and transient steroid responsiveness. However, recurrence of symptoms and subsequent histopathological evaluation confirmed the presence of extranodal orbital T-cell lymphoma. This case underscores the critical importance of maintaining a high index of suspicion for malignancy in steroid-responsive orbital syndromes, especially when atypical features or relapses occur. Early biopsy and multidisciplinary coordination enabled timely initiation of CHOEP chemotherapy, leading to slight clinical improvement. This report adds to the growing body of literature emphasizing the masquerade potential of lymphoid malignancies in orbital inflammation.
Conclusion:
Orbital T-cell lymphoma can mimic benign inflammatory conditions such as orbital cellulitis. Prompt biopsy and multidisciplinary evaluation are crucial for accurate diagnosis and timely initiation of appropriate treatment.
DOI: 10.6084/m9.figshare.30617177
title: Supplementary Material for: Arg339Gln is a Recurrent Variant in Rare Combined Oxidative Phosphorylation Deficiency 4: A New Patient with Biallelic TUFM Gene Variant

description: Introduction: Combined oxidative phosphorylation deficiency 4 (COXPD4, OMIM#610678) is a very rare mitochondrial disorder caused by biallelic variants in TUFM gene. The condition is characterized by microcephaly, severe early-onset lactic acidosis, and progressive, often fatal, infantile encephalopathy. To date, only eight patients with biallelic TUFM variants have been reported. 
Case Presentation: We present a case of a female infant with microcephaly who died from severe lactic acidosis at 7 months of age. Genetic analysis revealed homozygous c.1016G&gt;A (p.Arg339Gln) variant in the TUFM gene, which has previously been reported in three other COXPD4 cases. This is the fourth publication describing the same variant in this rare disorder, suggesting that it is a recurrent variant in COXPD4 patients.
Conclusion: Arg339Gln variant was found in all COXPD4 patients from Turkey and is considered a potential founder mutation. This report aims to contribute to the phenotypic spectrum of COXPD4, explore the frequency and clinical presentation of the reported variants, enhance the understanding of genotype-phenotype correlations, and raise awareness of rare mitochondrial disorders.
DOI: 10.6084/m9.figshare.30617177.v1
title: Supplementary Material for: Arg339Gln is a Recurrent Variant in Rare Combined Oxidative Phosphorylation Deficiency 4: A New Patient with Biallelic TUFM Gene Variant

description: Introduction: Combined oxidative phosphorylation deficiency 4 (COXPD4, OMIM#610678) is a very rare mitochondrial disorder caused by biallelic variants in TUFM gene. The condition is characterized by microcephaly, severe early-onset lactic acidosis, and progressive, often fatal, infantile encephalopathy. To date, only eight patients with biallelic TUFM variants have been reported. 
Case Presentation: We present a case of a female infant with microcephaly who died from severe lactic acidosis at 7 months of age. Genetic analysis revealed homozygous c.1016G&gt;A (p.Arg339Gln) variant in the TUFM gene, which has previously been reported in three other COXPD4 cases. This is the fourth publication describing the same variant in this rare disorder, suggesting that it is a recurrent variant in COXPD4 patients.
Conclusion: Arg339Gln variant was found in all COXPD4 patients from Turkey and is considered a potential founder mutation. This report aims to contribute to the phenotypic spectrum of COXPD4, explore the frequency and clinical presentation of the reported variants, enhance the understanding of genotype-phenotype correlations, and raise awareness of rare mitochondrial disorders.
DOI: 10.15468/dl.nqksqv
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Chrosomus eos",
 "HasCoordinate is true",
 "Geometry POLYGON((-78 12, -73 12, -73 0, -78 0, -78 12))"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0032680-251025141854904/datasets/export for details.
DOI: 10.5281/zenodo.14970354
title: Data for article "Droplet electrocoalescence as a robust tool for in situ examination of hydrogel microparticles in microuidic devices"

description: The repository contains all data required to reproduce the results in article "Droplet electrocoalescence as a robust tool for in situ examination of hydrogel microparticles in microfluidic devices", including a microscope image sequence files, which you can analyze using Python scripts for video processing and analysis using OpenCV from github repository https://github.com/Andrey12133/droplets-tracking.git.
DOI: 10.5281/zenodo.14970355
title: Data for article "Droplet electrocoalescence as a robust tool for in situ examination of hydrogel microparticles in microuidic devices"

description: The repository contains all data required to reproduce the results in article "Droplet electrocoalescence as a robust tool for in situ examination of hydrogel microparticles in microfluidic devices", including a microscope image sequence files, which you can analyze using Python scripts for video processing and analysis using OpenCV from github repository https://github.com/Andrey12133/droplets-tracking.git.
DOI: 10.26275/evaa-akgj
title: Human vagus nerve anatomical reconstruction using microCT and immunohistochemistry - f008

description: SPARC REVA FEINSTEIN
description: Data created as part of the SPARC REVA award. The dataset includes anatomical images and videos, microCT scans across the length of the nerve and IHC image across multiple levels.
DOI: 10.15468/dl.a97hhj
title: Occurrence Download

description: A dataset containing 22959 species occurrences available in GBIF matching the query:
{
 "and" : [
 "OccurrenceStatus is Present",
 "TaxonKey is Laminaria digitata"
 ]
}

 The dataset includes 22959 records from 249 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0032681-251025141854904/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.