cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q2r49rvj
title: BindingDB Entry 50039917: N-Pyridyl and Pyrimidine Benzamides as KCNQ2/Q3 Potassium Channel Openers for the Treatment of Epilepsy.

description: Small molecule binding data for protein Voltage-gated potassium channel, Voltage-gated potassium channel beta subunit Mink/subunit Kv7.1, Voltage-gated potassium channel subunit Kv7.2/Kv7.3, and Voltage-gated sodium channel subunit Nav1.5, Uniprot O43525, O43526, P15382, P51787, Q12809, and Q14524
DOI: 10.7270/q2tx3g9b
title: BindingDB Entry 50039103: 3-Aryl-4-(arylhydrazono)-1H-pyrazol-5-ones: Highly ligand efficient and potent inhibitors of GSK3beta.

description: Small molecule binding data for protein Cyclin-dependent kinase 2, Glycogen synthase kinase-3, Hepatocyte growth factor receptor, Interleukin-1 receptor-associated kinase 4, Mitogen-activated protein kinase 10, PI3-kinase subunit gamma, Rho-associated protein kinase, Serine/threonine-protein kinase PLK1, Tyrosine-protein kinase JAK2, Tyrosine-protein kinase SYK, Tyrosine-protein kinase receptor FLT3, VEGF-receptor 2 and tyrosine-protein kinase SRC, and Vascular endothelial growth factor receptor 2, Uniprot O60674, P08581, P12931, P24941, P35968, P36888, P43405, P48736, P49841, P53350, P53779, Q13464, and Q9NWZ3
DOI: 10.7270/q2v69k9x
title: BindingDB Entry 50037219: Guanidino N-substituted and N,N-disubstituted derivatives of the kappa-opioid antagonist GNTI.

description: Small molecule binding data for protein Delta-type opioid receptor, Kappa-type opioid receptor, and Mu-type opioid receptor, Uniprot P35372, P41143, and P41145
DOI: 10.7270/q2vd7096
title: BindingDB Entry 50038184: Synthesis and characterization of 8-ethynyl-1,3-dihydro-benzo[b][1,4]diazepin-2-one derivatives: part 2. New potent non-competitive metabotropic glutamate receptor 2/3 antagonists.

description: Small molecule binding data for protein Metabotropic glutamate receptor 2 (mGluR2) and Metabotropic glutamate receptor 8 (mGlu8), Uniprot P70579 and Q14416
DOI: 10.7270/q2vx0hkh
title: BindingDB Entry 50039916: The binding of C5-alkynyl and alkylfurano[2,3-d]pyrimidine glucopyranonucleosides to glycogen phosphorylase b: synthesis, biochemical and biological assessment.

description: Small molecule binding data for protein Glycogen phosphorylase, muscle form and Muscle glycogen phosphorylase, Uniprot P00489 and P11217
DOI: 10.7270/q2zk5hns
title: BindingDB Entry 50039102: Discovery of potent and bioavailable GSK-3beta inhibitors.

description: Small molecule binding data for protein Aurora kinase B/Inner centromere protein, CDC2-like kinase 3 (CLK3), CDK7/Cyclin H/MNAT1, CDK8/Cyclin C, Cell division cycle 2-like protein kinase 6, Cyclin-Dependent Kinase 5 (CDK5), Cyclin-dependent kinase 2, Cyclin-dependent kinase 3 (CDK3), Cyclin-dependent kinase 9, Dual specificity protein kinase CLK2, Dual specificity protein kinase CLK4, Dual specificity protein kinase TTK, Dual specificty protein kinase CLK1, Dual-specificity tyrosine-regulated kinases 1B, Extracellular signal-regulated kinase 5 (ERK5), Glycogen synthase kinase-3, Interferon-induced, double-stranded RNA-activated protein kinase, MAP kinase ERK2, Mitogen-activated protein kinase 15, Mitogen-activated protein kinase 3, Mitogen-activated protein kinase 4, Mitogen-activated protein kinase 6, Protein kinase C alpha type, Serine/threonine-protein kinase Aurora, Serine/threonine-protein kinase Aurora-C, Serine/threonine-protein kinase PCTAIRE-1, Serine/threonine-protein kinase PCTAIRE-2, Serine/threonine-protein kinase PCTAIRE-3, Serine/threonine-protein kinase PLK1, Serine/threonine-protein kinase PLK3, Serine/threonine-protein kinase PLK4, and Tyrosine-protein kinase STK16 (STK16), Uniprot O00444, O14965, O75716, P17252, P19525, P24941, P27361, P28482, P31152, P33981, P49336, P49759, P49760, P49761, P49840, P49841, P50613, P50750, P53350, Q00526, Q00535, Q00536, Q00537, Q13164, Q16659, Q8TD08, Q96GD4, Q9BWU1, Q9H4B4, Q9HAZ1, Q9UQB9, and Q9Y463
DOI: 10.7270/q2zw1mp2
title: BindingDB Entry 50037218: Discovery of 1-(2-aminomethylphenyl)-3-trifluoromethyl-N- [3-fluoro-2'-(aminosulfonyl)[1,1'-biphenyl)]-4-yl]-1H-pyrazole-5-carboxyamide (DPC602), a potent, selective, and orally bioavailable factor Xa inhibitor(1).

description: Small molecule binding data for protein Alpha-chymotrypsin, Beta-chymotrypsin, Coagulation factor IX and X, Coagulation factor VII, Coagulation factor X/antithrombin III, Plasma kallikrein (KLKB1), Plasminogen, Prothrombin, Tissue-type plasminogen activator, Trypsin-1, Urokinase-type plasminogen activator, and Vitamin K-dependent protein C, Uniprot P00734, P00740, P00742, P00747, P00749, P00750, P00766, P03952, P04070, P07477, and P08709
DOI: 10.7270/q21g0n7r
title: BindingDB Entry 50039118: "Carba"-analogues of fentanyl are opioid receptor agonists.

description: Small molecule binding data for protein Delta-type opioid receptor, Kappa-type opioid receptor, Mu-type opioid receptor, Nociceptin/mu opioid receptor, Opioid receptors; mu & delta, and mu/kappa opioid receptor, Uniprot P32300, P33533, P33535, P35372, P41144, P41145, and P97266
DOI: 10.7270/q22b9003
title: BindingDB Entry 50039110: Identification of (beta-carboxyethyl)-rhodanine derivatives exhibiting peroxisome proliferator-activated receptor gamma activity.

description: Small molecule binding data for protein Peroxisome proliferator-activated receptor, Uniprot P37231
DOI: 10.7270/q22n531c
title: BindingDB Entry 50037225: Three-dimensional quantitative structure-activity relationship analyses of peptide substrates of the mammalian H+/peptide cotransporter PEPT1.

description: Small molecule binding data for protein Oligopeptide transporter small intestine isoform, Uniprot P46059
DOI: 10.7270/q22z16cp
title: BindingDB Entry 50038190: 1H-Pyrazolo[3,4-g]hexahydro-isoquinolines as selective glucocorticoid receptor antagonists with high functional activity.

description: Small molecule binding data for protein Glucocorticoid receptor, Uniprot P04150
DOI: 10.7270/q2542pjr
title: BindingDB Entry 50039117: Synthesis and in vitro biological evaluation of carbonyl group-containing inhibitors of vesicular acetylcholine transporter.

description: Small molecule binding data for protein Sigma-1 receptor and Vesicular acetylcholine transporter, Uniprot P81721 and Q60492
DOI: 10.7270/q26d5tqv
title: BindingDB Entry 50037224: Computer modeling of selective regions in the active site of nitric oxide synthases: implication for the design of isoform-selective inhibitors.

description: Small molecule binding data for protein Nitric Oxide Synthase, brain, Nitric Oxide Synthase, endothelial, and Nitric Oxide Synthase, inducible, Uniprot P29473, P29475, P29476, P29477, and P35228
DOI: 10.7270/q2736s0m
title: BindingDB Entry 50039921: Discovery of a potent thiadiazole class of histamine h3 receptor antagonist for the treatment of diabetes.

description: Small molecule binding data for protein Histamine H3 receptor and Histamine receptor (H3), Uniprot P58406 and Q9Y5N1
DOI: 10.7270/q28w3f7q
title: BindingDB Entry 50039116: A virtual screening hit reveals new possibilities for developing group III metabotropic glutamate receptor agonists.

description: Small molecule binding data for protein Metabotropic glutamate receptor 2 (mGluR2), Metabotropic glutamate receptor 4 (mGlu4), Metabotropic glutamate receptor 6 (mGlu6), Metabotropic glutamate receptor 7 (mGlu7), and Metabotropic glutamate receptor 8 (mGlu8), Uniprot P31423, P35349, P35400, P70579, and Q14416
DOI: 10.7270/q29g5npz
title: BindingDB Entry 50038196: Design, synthesis, and biological evaluation of (hydroxyphenyl)naphthalene and -quinoline derivatives: potent and selective nonsteroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 1 (17beta-HSD1) for the treatment of estrogen-dependent diseases.

description: Small molecule binding data for protein Cytochrome P450 1A, Cytochrome P450 2B6, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), Cytochrome P450 3A, Estradiol 17-beta-dehydrogenase 1 (17beta-HSD1), and Estradiol 17-beta-dehydrogenase 2, Uniprot P05177, P08684, P10635, P11712, P14061, P20813, P33261, and P37059
DOI: 10.7270/q29w0gjb
title: BindingDB Entry 50039928: The First Dual ChE/FAAH Inhibitors: New Perspectives for Alzheimer's Disease?

description: Small molecule binding data for protein Acetylcholinesterase, Anandamide amidohydrolase, Cholinesterase, and Fatty-acid amide hydrolase 1 (FAAH), Uniprot O00519, P06276, P22303, and P97612
DOI: 10.7270/q2b56kfk
title: BindingDB Entry 50037223: Synthesis and structure-activity relationship of aminobenzophenones. A novel class of p38 MAP kinase inhibitors with high antiinflammatory activity.

description: Small molecule binding data for protein Mitogen-activated protein kinase 14, Uniprot Q16539
DOI: 10.7270/q2dn460w
title: BindingDB Entry 50039115: Sulfonamide linked neoglycoconjugates--a new class of inhibitors for cancer-associated carbonic anhydrases.

description: Small molecule binding data for protein Carbonic anhydrase, Carbonic anhydrase 12, Carbonic anhydrase 2, and Carbonic anhydrase 9, Uniprot O43570, P00915, P00918, and Q16790
DOI: 10.7270/q2f76df4
title: BindingDB Entry 50038195: Synthesis, in vitro characterization, and radiolabeling of reboxetine analogs as potential PET radioligands for imaging the norepinephrine transporter.

description: Small molecule binding data for protein Serotonin and norepinephrine transporters (SERT/NET), Sodium-dependent dopamine transporter, and Sodium-dependent noradrenaline transporter, Uniprot P23975, P31645, and Q01959
DOI: 10.7270/q2fn177m
title: BindingDB Entry 50039927: Virtual Screening and X-ray Crystallography for Human Kallikrein 6 Inhibitors with an Amidinothiophene P1 Group.

description: Small molecule binding data for protein Kallikrein 6, Uniprot Q92876
DOI: 10.7270/q2jd4xr8
title: BindingDB Entry 50039114: Tetrahydroindolizinone NK1 antagonists.

description: Small molecule binding data for protein Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), Cytochrome P450 3A, Neurokinin 1 receptor, and Pregnane X receptor (PXR), Uniprot O75469, P08684, P10635, P11712, and P25103
DOI: 10.7270/q2k0755v
title: BindingDB Entry 50038194: Discovery of a novel class of 1,3-dioxane-2-carboxylic acid derivatives as subtype-selective peroxisome proliferator-activated receptor alpha (PPARalpha) agonists.

description: Small molecule binding data for protein Peroxisome proliferator-activated receptor, Peroxisome proliferator-activated receptor alpha, Peroxisome proliferator-activated receptor alpha (PPAR alpha), Peroxisome proliferator-activated receptor delta (PPAR delta), and Peroxisome proliferator-activated receptor gamma, Uniprot P23204, P37231, P37238, Q03181, and Q07869
DOI: 10.7270/q2kd1zzj
title: BindingDB Entry 50039926: Inhibitors for Bacterial Cell-Wall Recycling.

description: Small molecule binding data for protein Beta-hexosaminidase and Membrane-bound lytic murein transglycosylase B, Uniprot P41052 and Q9HZK0
DOI: 10.7270/q2p55pg0
title: BindingDB Entry 50039113: Novel benzothiophene H1-antihistamines for the treatment of insomnia.

description: Small molecule binding data for protein Cytochrome P450 2D6 (2D6), Cytochrome P450 3A, Histamine H1 receptor, Muscarinic acetylcholine receptor M1, and Voltage-gated potassium channel, Uniprot P08684, P10635, P11229, P35367, and Q12809
DOI: 10.7270/q2pr7wv1
title: BindingDB Entry 50038193: Rational design of 4-amino-5,6-diaryl-furo[2,3-d]pyrimidines as potent glycogen synthase kinase-3 inhibitors.

description: Small molecule binding data for protein Glycogen Synthase Kinase-3, beta, Glycogen synthase kinase-3, and Vascular endothelial growth factor receptor 2, Uniprot P18266, P35968, and P49841
DOI: 10.7270/q2q52qp8
title: BindingDB Entry 50039925: Discovery of 1,3-Diaminobenzenes as Selective Inhibitors of Platelet Activation at the PAR1 Receptor.

description: Small molecule binding data for protein Proteinase-activated receptor 1 (PAR1), Uniprot P25116
DOI: 10.7270/q2sx6f6d
title: BindingDB Entry 50039112: Single agents with designed combination chemotherapy potential: synthesis and evaluation of substituted pyrimido[4,5-b]indoles as receptor tyrosine kinase and thymidylate synthase inhibitors and as antitumor agents.

description: Small molecule binding data for protein Dihydrofolate reductase, Epidermal growth factor receptor, Platelet-derived growth factor receptor beta, Thymidylate synthase, Tyrosine-protein kinase receptor FLT3, Vascular endothelial growth factor receptor, and Vascular endothelial growth factor receptor 2, Uniprot L7RSL3, P00374, P00533, P04818, P09619, P17948, P35968, and P36888
DOI: 10.7270/q2td9z6w
title: BindingDB Entry 50038192: Synthesis and SAR of pyridazinone-substituted phenylalanine amide alpha4 integrin antagonists.

description: Small molecule binding data for protein Fibronectin receptor beta/Integrin alpha-4 and Integrin alpha-4/beta7, Uniprot P05556, P13612, and P26010
DOI: 10.7270/q2tx3gf4
title: BindingDB Entry 50039924: NOpiates: Novel Dual Action Neuronal Nitric Oxide Synthase Inhibitors with µ-Opioid Agonist Activity.

description: Small molecule binding data for protein Mu-type opioid receptor, Nitric oxide synthase, brain, Nitric oxide synthase, inducible, and Nitric-oxide synthase (endothelial and brain), Uniprot P29475, P35228, and P35372
DOI: 10.7270/q2wq04sw
title: BindingDB Entry 50039120: Toward the development of potent and selective bisubstrate inhibitors of protein arginine methyltransferases.

description: Small molecule binding data for protein Protein-arginine N-methyltransferase 1 and SET domain-containing protein 7/9 (Set7/9), Uniprot Q8WTS6
DOI: 10.7270/q2xp75w8
title: BindingDB Entry 50039111: Through the"gatekeeper door": exploiting the active kinase conformation.

description: Small molecule binding data for protein AKT/p21CIP1, Cyclin-dependent kinase 2, Mitogen-activated protein kinase 14, Serine/threonine-protein kinase Aurora, Serine/threonine-protein kinase Chk1, Serine/threonine-protein kinase PLK1, Serine/threonine-protein kinase Sgk1, VEGF-receptor 2 and tyrosine-protein kinase SRC, and Vascular endothelial growth factor receptor 2, Uniprot O00141, O14757, O14965, P12931, P24941, P31749, P35968, P53350, and Q16539
DOI: 10.7270/q2z60pw9
title: BindingDB Entry 50038191: Tyramine fragment binding to BACE-1.

description: Small molecule binding data for protein Beta-secretase 1, Uniprot P56817
DOI: 10.7270/q2zp475v
title: BindingDB Entry 50039923: Discovery of a Novel Class of Bicyclo[3.1.0]hexanylpiperazines as Noncompetitive Neuropeptide Y Y1 Antagonists.

description: Small molecule binding data for protein Neuropeptide Y receptor type 1, Uniprot P25929
DOI: 10.7270/q20g3m4t
title: BindingDB Entry 50039127: Discovery of a selective small-molecule melanocortin-4 receptor agonist with efficacy in a pilot study of sexual dysfunction in humans.

description: Small molecule binding data for protein Melanocortin receptor 3 (MC3R), Melanocortin receptor 4, Melanocortin receptor 5 (MC5R), Melanocyte-stimulating hormone receptor, and Voltage-gated potassium channel, Uniprot P32245, P33032, P41968, Q01726, and Q12809
DOI: 10.7270/q21r6r8g
title: BindingDB Entry 50037234: Synthesis and flow cytometric evaluation of novel 1,2,3,4-tetrahydroisoquinoline conformationally constrained analogues of nitrobenzylmercaptopurine riboside (NBMPR) designed for probing its conformation when bound to the es nucleoside transporter.

description: Small molecule binding data for protein Equilibrative Nucleoside Transporter 1 (ENT1), Uniprot Q99808
DOI: 10.7270/q21z458r
title: BindingDB Entry 50038198: Synthesis and structure-activity relationship studies in peripheral benzodiazepine receptor ligands related to alpidem.

description: Small molecule binding data for protein Peripheral-Type Benzodiazepine Receptor, Uniprot P16257
DOI: 10.7270/q22f7phc
title: BindingDB Entry 50039930: Defining the mechanism of action and enzymatic selectivity of psammaplin A against its epigenetic targets.

description: Small molecule binding data for protein DNA (cytosine-5)-methyltransferase 1 (DNMT1), Histone deacetylase, Histone deacetylase 1, Histone deacetylase 7 (HDAC7), Histone deacetylase 8, and Histone deacetylase-like amidohydrolase, Uniprot A0A024QZ26, P26358, Q13547, Q70I53, Q8WUI4, Q9BY41, and Q9UBN7
DOI: 10.7270/q2474btp
title: BindingDB Entry 50039126: Discovery of novel 6,6-heterocycles as transient receptor potential vanilloid (TRPV1) antagonists.

description: Small molecule binding data for protein Mitogen-activated protein kinase 3, Transient receptor potential cation channel subfamily V member 1, and Vanilloid receptor, Uniprot O35433, P27361, and Q8NER1
DOI: 10.7270/q25h7h06
title: BindingDB Entry 50037233: Synthesis and structure-affinity relationships of novel N-(1-ethyl-4-methylhexahydro-1,4-diazepin-6-yl)pyridine-3-carboxamides with potent serotonin 5-HT3 and dopamine D2 receptor antagonistic activity.

description: Small molecule binding data for protein Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor, Dopamine receptor, HTR4, and Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor, Uniprot O70528, P19020, P35563, P61169, and Q9JJ16
DOI: 10.7270/q25q4wz7
title: BindingDB Entry 50038197: Nitro as a novel zinc-binding group in the inhibition of carboxypeptidase A.

description: Small molecule binding data for protein Carboxypeptidase A1, Uniprot P15085
DOI: 10.7270/q2668f73
title: BindingDB Entry 50039929: Discovery and evaluation of a non-Zn chelating, selective matrix metalloproteinase 13 (MMP-13) inhibitor for potential intra-articular treatment of osteoarthritis.

description: Small molecule binding data for protein A disintegrin and metalloproteinase with thrombospondin motifs 4 (ADAMTS-4), ADAM17, Collagenase, Matrix Metalloproteinase-8 (MMP-8), Matrix metalloproteinase-1 (MMP1), Matrix metalloproteinase-12 (MMP12), Matrix metalloproteinase-14 (MMP14), Matrix metalloproteinase-7 (MMP7), and Stromelysin-1, Uniprot O75173, P03956, P08253, P08254, P09237, P14780, P22894, P39900, P45452, P50281, and P78536
DOI: 10.7270/q27w6d57
title: BindingDB Entry 50039125: Novel 8-(furan-2-yl)-3-substituted thiazolo [5,4-e][1,2,4] triazolo[1,5-c] pyrimidine-2(3H)-thione derivatives as potential adenosine A(2A) receptor antagonists.

description: Small molecule binding data for protein Adenosine receptor A1 and Adenosine receptor A2a, Uniprot P29274 and P30542
DOI: 10.7270/q28g8mjk
title: BindingDB Entry 50038204: A set of phosphatase-inert"molecular rulers" to probe for bivalent mannose 6-phosphate ligand-receptor interactions.

description: Small molecule binding data for protein Insulin-like growth factor II receptor, Uniprot P11717
DOI: 10.7270/q29024v1
title: BindingDB Entry 50039936: Design and synthesis of active site inhibitors of the human farnesyl pyrophosphate synthase: apoptosis and inhibition of ERK phosphorylation in multiple myeloma cells.

description: Small molecule binding data for protein Farnesyl diphosphate synthase and Geranylgeranyl Diphosphate Synthase (GGPPS), Uniprot O95749 and P14324
DOI: 10.7270/q2959j96
title: BindingDB Entry 50037232: 2,6-Dimethyltyrosine analogues of a stereodiversified ligand library: highly potent, selective, non-peptidic mu opioid receptor agonists.

description: Small molecule binding data for protein Delta-type opioid receptor, Mu-type opioid receptor, and mu/kappa opioid receptor, Uniprot P35372, P41143, and P41144
DOI: 10.7270/q2cn74v3
title: BindingDB Entry 50039124: Identification and hit-to-lead exploration of a novel series of histamine H4 receptor inverse agonists.

description: Small molecule binding data for protein Histamine H1 receptor, Histamine H2 Receptor, Histamine receptor (H3), and Histamine receptor (H4), Uniprot P25021, P35367, Q9H3N8, and Q9Y5N1
DOI: 10.7270/q2dz0915
title: BindingDB Entry 50037231: 3-(alphaR)-alpha-((2S,5R)-4-allyl-2,5-dimethyl-1-piperazinyl)-3-hydroxybenzyl)-N-alkyl-N-arylbenzamides: potent, non-peptidic agonists of both the micro and delta opioid receptors.

description: Small molecule binding data for protein Nociceptin/mu opioid receptor and Opioid receptors; mu & delta, Uniprot P33533 and P33535
DOI: 10.7270/q2hd7wmw
title: BindingDB Entry 50039123: (S)-3-(4-(2-(5-Methyl-2-phenyloxazol-4-yl)ethoxy)phenyl)-2-(piperazin-1-yl) propanoic acid compounds: synthesis and biological evaluation of dual PPARalpha/gamma agonists.

description: Small molecule binding data for protein Peroxisome proliferator-activated receptor and Peroxisome proliferator-activated receptor alpha (PPAR alpha), Uniprot P37231 and Q07869
DOI: 10.7270/q2j10411
title: BindingDB Entry 50038202: A-803467, a potent and selective Nav1.8 sodium channel blocker, attenuates neuropathic and inflammatory pain in the rat.

description: Small molecule binding data for protein 5-Hydroxytryptamine receptor 2A (5-HT2A), 5-Hydroxytryptamine receptor 2C (5-HT2C), 5-Hydroxytryptamine receptor 6 (5-HT6), 5-Hydroxytryptamine receptor 7 (5-HT7), 5-hydroxytryptamine receptor 1A, 5-hydroxytryptamine receptor 1B, Adenosine receptor A1, Adenosine receptor A2a, Adenosine receptor A3, Adrenergic alpha1B, Alpha-2A adrenergic receptor, Alpha-2B adrenergic receptor, C-C chemokine receptor type 1, Cannabinoid receptor 1, Cannabinoid receptor 2, Delta-type opioid receptor, Dopamine D1 and D2 receptor, Dopamine D5 receptor, Dopamine receptor, Dopamine receptor D2L/neurotensin receptor NTS1, EDNRA, Histamine H1 receptor, Histamine H2 Receptor, Interleukin-8 receptors, CXCR2, KCNQ (Kv7) potassium channel, Kappa-type opioid receptor, Mu-type opioid receptor, Muscarinic acetylcholine receptor, Muscarinic acetylcholine receptor M1, Muscarinic acetylcholine receptor M1/M5 chimeric protein, Muscarinic acetylcholine receptor M2, Muscarinic acetylcholine receptor M2 and M4, Nociceptin receptor, P2X purinoceptor 3, Purinergic receptor P2Y2, PurinergicP2X2/3, Serotonin (5-HT) receptor, Serotonin 3 (5-HT3) receptor, Sigma, Sodium channel alpha subunit, Transient receptor potential cation channel subfamily V member 1, Voltage-gated calcium channel subunit alpha Cav2.2, Voltage-gated sodium channel subunit Nav1.5, Voltage-gated sodium channel subunit alpha Nav1.2 (Nav1.2), Voltage-gated sodium channel subunit alpha Nav1.3 (Nav1.3), and Voltage-gated sodium channel subunit alpha Nav1.8, Uniprot O43525, O43526, P08172, P08173, P08908, P08912, P08913, P0DMS8, P11229, P14416, P18089, P20309, P21554, P21728, P21918, P25021, P25025, P25101, P28222, P28223, P28335, P29274, P30542, P32246, P34969, P34972, P35367, P35368, P35372, P35462, P41143, P41145, P41146, P41231, P46098, P47898, P50406, P56373, Q00975, Q14524, Q15858, Q62968, Q8NER1, Q99250, Q99720, Q9NY46, Q9UBL9, and Q9Y5Y9
DOI: 10.7270/q2jd4xt5
title: BindingDB Entry 50039934: Structure-activity relationships in human Toll-like receptor 2-specific monoacyl lipopeptides.

description: Small molecule binding data for protein Toll-like receptor 2 (TLR2), Uniprot O60603
DOI: 10.7270/q2jq11rg
title: BindingDB Entry 50037230: Design, synthesis, and biological activities of classical N-[4-[2-(2-amino-4-ethylpyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-l-glutamic acid and its 6-methyl derivative as potential dual inhibitors of thymidylate synthase and dihydrofolate reductase and as potential antitumor agents.

description: Small molecule binding data for protein Dihydrofolate reductase and Thymidylate synthase, Uniprot P00374, P00381, and P04818
DOI: 10.7270/q2n58nbm
title: BindingDB Entry 50039122: Complexity in influenza virus targeted drug design: interaction with human sialidases.

description: Small molecule binding data for protein Sialidase 2, Uniprot Q9Y3R4
DOI: 10.7270/q2ns0vs3
title: BindingDB Entry 50038201: Nootropic alpha7 nicotinic receptor allosteric modulator derived from GABAA receptor modulators.

description: Small molecule binding data for protein GABA receptor alpha-1/beta-2/gamma-2 subunit, GABA receptor alpha-2/beta-3/gamma-2 subunit, Neuronal acetylcholine receptor, and Neuronal acetylcholine receptor protein alpha-7 subunit, Uniprot P14867, P18507, P28472, P36544, P47869, P47870, and Q05941