cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.6967814.v1
title: Free tissue flaps in head and neck reconstruction: clinical application and analysis of 93 patients of a single institution

description: Abstract Introduction Reconstruction with a free flap is routine in head and neck surgery because of better functional outcomes, improved esthetics, and generally higher success rates. Objective To evaluate the clinical outcomes in patients undergoing different microvascular free flap reconstructions. Methods This was a retrospective study of 93 patients undergoing reconstructions with free flaps from 2007 to 2015. Four types of free flap were performed: anterolateral thigh (76.3%), radial forearm (16.1%), fibula (4.3%) and jejunum (3.3%). Patients' demographic data were collected, and the outcomes measured included flap survival and complications. Postoperative functional and oncological outcome were also analyzed. Results The patients included 73 men and 20 women, with a mean age of 56.1 years. The most common tumor location was the tongue. Squamous cell carcinoma represented the vast majority of the diagnosed tumors (89.2%). The most common recipient vessels were the superior thyroid artery (77.4%) and the internal jugular vein (91.4%). Nine patients required emergency surgical re-exploration and the overall flap success rate was 90.3%. Venous thrombosis was the most common cause for re-exploration. Other complications included wound infection (5.4%), wound dehiscence (1.1%), partial flap necrosis (9.7%), fistula formation (10.8%), and 1 bleeding (1.1%). The majority of patients had satisfactory cosmetic and functional results of both donor site and recipient site after 46.7 months of mean follow-up. Conclusion Microsurgical free flap is shown to be a valuable and reliable method in head and neck surgery. It can be used safely and effectively with minimal morbidity in selected patients. The reconstruction can be performed by appropriately skilled surgeons with acceptable outcomes. Success rate appears to increase as clinical experience is gained.
DOI: 10.6084/m9.figshare.7492100
title: Co-occurrence of 3 different resistance plasmids in a multi-drug resistant <i>Cronobacter sakazakii</i> isolate causing neonatal infections

description: <i>Cronobacter sakazakii</i> 505108 was isolated from a sputum specimen of a neonate with severe pneumonia. <i>C. sakazakii</i> 505108 co-harbors 3 resistance plasmids of the IncHI2, IncX3, and IncFIB incomparability groups, respectively. These 3 plasmids have acquired several accessory modules, which carry an extremely large number of resistance genes, especially including those involved in resistance to carbapenems, aminoglycoside, tetracyclines, and phenicols and sulphonamide/trimethoprim. These plasmid-borne antibiotic resistance genes were associated with insertion sequences, integrons, and transposons, indicating that the assembly and mobilization of the corresponding accessory modules with complex chimera structures are facilitated by transposition and/or homologous recombination. This is the first report of fully sequence plasmids in clinical <i>Cronobacter</i>, which provides a deeper insight into plasmid-mediated multi-drug resistance in <i>Cronobacter</i> from hospital settings.
DOI: 10.6084/m9.figshare.12210746
title: Synthesis and performance of AM/SSS/THDAB as clay hydration dispersion inhibitor

description: Abstract In this paper, a novel zwitterionic copolymer AM/SSS/THDAB clay hydration dispersion inhibitor was synthesized by copolymerization of tris hydroxyethyl diallyl ammonium bromide (THDAB), sodium p-styrene sulfonate (SSS) and acrylamide (AM) initiated in an aqueous solution. The copolymer was characterized by FT-IR, GPC, TGA-DSC and SEM. Results demonstrated that molecular weight of AM/SSS/THDAB was 43674 g/mol and its temperature resistance ability was up to 225 °C. Evaluation experiments showed that AM/SSS/THDAB has an excellent clay hydration inhibitive performance. Methods including particle size analysis and SEM were utilized to study its dispersion inhibition mechanism by using sodium montmorillonite (Na-MMT). Results indicated that the micro-structure of Na-MMT has been successfully changed by AM/SSS/THDAB. In a word, the superior inhibition property makes the novel clay hydration dispersion inhibitor promised in water-based drilling fluids.
DOI: 10.6084/m9.figshare.17120033
title: Additional file 2 of Identification of proteins associated with bast fiber growth of ramie by differential proteomic analysis

description: Additional file 2.
DOI: 10.6084/m9.figshare.21647927.v1
title: Adaptive Algorithm for Multi-armed Bandit Problem with High-dimensional Covariates

description: This paper studies an important sequential decision making problem known as the multi-armed stochastic bandit problem with covariates. Under a linear bandit framework with high-dimensional covariates, we propose a general multi-stage arm allocation algorithm that integrates both arm elimination and randomized assignment strategies. By employing a class of high-dimensional regression methods for coefficient estimation, the proposed algorithm is shown to have near optimal finite-time regret performance under a new study scope that requires neither a margin condition nor a reward gap condition for competitive arms. Based on the synergistically verified benefit of the margin, our algorithm exhibits adaptive performance that automatically adapts to the margin and gap conditions, and attains optimal regret rates simultaneously for both study scopes, without or with the margin, up to a logarithmic factor. Besides the desirable regret performance, the proposed algorithm simultaneously generates useful coefficient estimation output for competitive arms and is shown to achieve both estimation consistency and variable selection consistency. Promising empirical performance is demonstrated through extensive simulation and two real data evaluation examples.
DOI: 10.6084/m9.figshare.21647927.v2
title: Adaptive Algorithm for Multi-Armed Bandit Problem with High-Dimensional Covariates

description: This article studies an important sequential decision making problem known as the multi-armed stochastic bandit problem with covariates. Under a linear bandit framework with high-dimensional covariates, we propose a general multi-stage arm allocation algorithm that integrates both arm elimination and randomized assignment strategies. By employing a class of high-dimensional regression methods for coefficient estimation, the proposed algorithm is shown to have near optimal finite-time regret performance under a new study scope that requires neither a margin condition nor a reward gap condition for competitive arms. Based on the synergistically verified benefit of the margin, our algorithm exhibits adaptive performance that automatically adapts to the margin and gap conditions, and attains optimal regret rates simultaneously for both study scopes, without or with the margin, up to a logarithmic factor. Besides the desirable regret performance, the proposed algorithm simultaneously generates useful coefficient estimation output for competitive arms and is shown to achieve both estimation consistency and variable selection consistency. Promising empirical performance is demonstrated through extensive simulation and two real data evaluation examples. Supplementary materials for this article are available online.
DOI: 10.6084/m9.figshare.6967895.v1
title: Early Assessment of Right Ventricular Function in Systemic Lupus Erythematosus Patients using Strain and Strain Rate Imaging

description: Abstract Background: Right ventricular function is a crucial factor of the prognosis of systemic lupus erythematosus (SLE). Objectives: To evaluate the right ventricular function in SLE patients with different degrees of pulmonary hypertension (PH) by strain and strain rate imaging. Methods: A total of 102 SLE patients and 30 healthy volunteers were studied between October 2015 and May 2016. Patients were divided into three groups according to pulmonary artery systolic pressure (PASP) estimated by echocardiography: group control (A); PASP ≤ 30 mmHg (group B, n = 37); PASP 30-50 mmHg (mild PH; group C, n = 34); and PASP ≥ 50 mmHg (moderate-to-severe PH; group D, n = 31). Longitudinal peak systolic strain (ε) and strain rate (SR), including systolic strain rate (SRs), early diastolic strain rate (SRe) and late diastolic strain rate (SRa) were measured in the basal, middle and apical segments of the right ventricular free wall in participants by two-dimensional speckle tracking echocardiography (2D-STE) from the apical four-chamber view. A p &lt; 0.05 was set for statistical significance. Results: The parameters of ε, SRs, SRe, and SRa were significantly decreased in groups C and D compared with groups A and B. The ε of each segments was significantly lower in group D than in group C, while there were no differences in SRs, SRe and SRa between groups C and D. Conclusions: Strain and strain rate imaging could early detect the right ventricular dysfunction in SLE patients with PH, and provide important value for clinical therapy and prognosis of these patients. (Arq Bras Cardiol. 2018; [online].ahead print, PP.0-0)
DOI: 10.6084/m9.figshare.16928832
title: Additional file 10 of Phosphoproteome analysis reveals the involvement of protein dephosphorylation in ethylene-induced corolla senescence in petunia

description: Additional file 10.
DOI: 10.6084/m9.figshare.16928850
title: Additional file 4 of Phosphoproteome analysis reveals the involvement of protein dephosphorylation in ethylene-induced corolla senescence in petunia

description: Additional file 4.
DOI: 10.6084/m9.figshare.16928850.v1
title: Additional file 4 of Phosphoproteome analysis reveals the involvement of protein dephosphorylation in ethylene-induced corolla senescence in petunia

description: Additional file 4.
DOI: 10.6084/m9.figshare.17120033.v1
title: Additional file 2 of Identification of proteins associated with bast fiber growth of ramie by differential proteomic analysis

description: Additional file 2.
DOI: 10.6084/m9.figshare.12210746.v1
title: Synthesis and performance of AM/SSS/THDAB as clay hydration dispersion inhibitor

description: Abstract In this paper, a novel zwitterionic copolymer AM/SSS/THDAB clay hydration dispersion inhibitor was synthesized by copolymerization of tris hydroxyethyl diallyl ammonium bromide (THDAB), sodium p-styrene sulfonate (SSS) and acrylamide (AM) initiated in an aqueous solution. The copolymer was characterized by FT-IR, GPC, TGA-DSC and SEM. Results demonstrated that molecular weight of AM/SSS/THDAB was 43674 g/mol and its temperature resistance ability was up to 225 °C. Evaluation experiments showed that AM/SSS/THDAB has an excellent clay hydration inhibitive performance. Methods including particle size analysis and SEM were utilized to study its dispersion inhibition mechanism by using sodium montmorillonite (Na-MMT). Results indicated that the micro-structure of Na-MMT has been successfully changed by AM/SSS/THDAB. In a word, the superior inhibition property makes the novel clay hydration dispersion inhibitor promised in water-based drilling fluids.
DOI: 10.6084/m9.figshare.16928847
title: Additional file 3 of Phosphoproteome analysis reveals the involvement of protein dephosphorylation in ethylene-induced corolla senescence in petunia

description: Additional file 3.
DOI: 10.6084/m9.figshare.16928865.v1
title: Additional file 9 of Phosphoproteome analysis reveals the involvement of protein dephosphorylation in ethylene-induced corolla senescence in petunia

description: Additional file 9.
DOI: 10.6084/m9.figshare.12210428
title: Does Cereal crops asymmetrically affect Agriculture gross domestic product in Pakistan? Using NARDL model approach

description: ABSTRACT: This study contributes to the extant literature on the nexus among rice, maize and wheat production with agriculture gross domestic product (AGDP) of Pakistan. We use time series data from 1970 to 2017 and employ the Non-linear Autoregressive Distributed Lag (NARDL) model. Short run and long run shocks between the selected variables and result’s is checked through the co-integration and nonlinear error correction model.Autoregressive distributed lag bound testing approach for co-integration and to find the relationship between variables Granger causality test is applied.Our results confirm co-integration, positive shocks results show that rice, maize and wheat production have significantly influence on AGDP. The asymmetrically positive shocks of three crops have neutral effect on AGDP. While in symmetric results show the unidirectional effect between rice, maize production with AGDP and wheat production do not have ganger causality with AGDP. Finally, results depict that wheat, maize and rice production significantly contributes to agricultural GDP in the case of Pakistan.
DOI: 10.6084/m9.figshare.6443558
title: Additional file 2: of Distinct sperm nucleus behaviors between genotypic and temperature-dependent sex determination males are associated with replication and expression-related pathways in a gynogenetic fish

description: Table S2. All proteins identified by iTRAQ approach and their annotation information in 6 databases. (XLS 4444 kb)
DOI: 10.6084/m9.figshare.12210428.v1
title: Does Cereal crops asymmetrically affect Agriculture gross domestic product in Pakistan? Using NARDL model approach

description: ABSTRACT: This study contributes to the extant literature on the nexus among rice, maize and wheat production with agriculture gross domestic product (AGDP) of Pakistan. We use time series data from 1970 to 2017 and employ the Non-linear Autoregressive Distributed Lag (NARDL) model. Short run and long run shocks between the selected variables and result’s is checked through the co-integration and nonlinear error correction model.Autoregressive distributed lag bound testing approach for co-integration and to find the relationship between variables Granger causality test is applied.Our results confirm co-integration, positive shocks results show that rice, maize and wheat production have significantly influence on AGDP. The asymmetrically positive shocks of three crops have neutral effect on AGDP. While in symmetric results show the unidirectional effect between rice, maize production with AGDP and wheat production do not have ganger causality with AGDP. Finally, results depict that wheat, maize and rice production significantly contributes to agricultural GDP in the case of Pakistan.
DOI: 10.6084/m9.figshare.12210668
title: miR-22 and cerebral microbleeds in brainstem and deep area are associated with depression one month after ischemic stroke

description: In this study, we aimed to explore the relationship among miR-22, deep cerebral microbleeds (CMBs), and post-stroke depression (PSD) 1 month after ischemic stroke. We consecutively recruited 257 patients with first-ever and recurrent acute cerebral infarction and performed PSD diagnosis in accordance with the Diagnostic and Statistical Manual IV criteria for depression. Clinical information, assessments of stroke severity, and imaging data were recorded on admission. We further detected plasma miR-22 using quantitative PCR and analyzed the relationship among miR-22, clinical data, and PSD using SPSS 23.0 software. Logistic regression showed that deep (OR=1.845, 95%CI: 1.006-3.386, P=0.047) and brain stem CMBs (OR=2.652, 95%CI: 1.110–6.921, P=0.040), as well as plasma miR-22 levels (OR=2.094, 95%CI: 1.066–4.115, P=0.032) were independent risk factors for PSD. In addition, there were significant differences in baseline National Institutes of Health Stroke Scale scores (OR=1.881, 95%CI: 1.180–3.011, P=0.007) and Widowhood scores (OR=1.903, 95%CI: 1.182–3.063, P=0.012). Analysis of the receiver operating curve (AUC=0.723, 95%CI: 0.562–0.883, P=0.016) revealed that miR-22 could predict PSD one month after ischemic stroke. Furthermore, plasma miR-22 levels in brainstem and deep CMBs patients showed an upward trend (P=0.028) relative to the others. Patients with acute ischemic stroke, having brainstem and deep cerebral microbleeds, or a higher plasma miR-22 were more likely to develop PSD. These findings indicate that miR-22 might be involved in cerebral microvascular impairment and post-stroke depression.
DOI: 10.6084/m9.figshare.13257459.v1
title: Additional file 4 of Transcriptome analysis identifies genes involved in the somatic embryogenesis of Eucalyptus

description: Additional file 4. Primers used for qRT-PCR.
DOI: 10.6084/m9.figshare.6967742.v1
title: The effects of inhaled NO on plasma vasoactive factor and CTnI level in rabbits with acute massive pulmonary embolism

description: Abstract Purpose: To investigate changes in the plasma concentrations of cardiac troponin I (CTnI), thromboxane A2 (TXA2), prostaglandin I2 (PGI2) and endothelin-1 (ET-1) in rabbits with massive pulmonary embolism (AMPE) and the impact of nitric oxide inhalation (NOI) on these indices. Methods: A total of 30 Japanese rabbits were used to construct an MPE model and were divided into 3 groups equally (n=10), including an EXP group (undergoing modeling alone), an NOI group (receiving NOI 2 h post-modeling) and a CON group (receiving intravenous physiological saline). Results: In the model group, plasma concentration of CTnI peaked at 16 h following modeling (0.46±0.10 µg/ml) and significantly decreased following NOI. Plasma levels of TXB2, PGI2 and ET-1 peaked at 12, 16 and 8 h following modeling, respectively, and significantly decreased at different time points (0, 2, 4, 8, 12, 16, 20 and 24 h) following NOI. A significant correlation was observed between the peak plasma CTnI concentration and peak TXB2, 6-keto prostaglandin F1α and ET-1 concentrations in the model and NOI groups. Conclusion: Increases in plasma TXA2, PGI2 and ET-1 levels causes myocardial damage in a rabbit model of AMPE; however, NOI effectively down regulates the plasma concentration of these molecules to produce a myocardial-protective effect.
DOI: 10.6084/m9.figshare.12210668.v1
title: miR-22 and cerebral microbleeds in brainstem and deep area are associated with depression one month after ischemic stroke

description: In this study, we aimed to explore the relationship among miR-22, deep cerebral microbleeds (CMBs), and post-stroke depression (PSD) 1 month after ischemic stroke. We consecutively recruited 257 patients with first-ever and recurrent acute cerebral infarction and performed PSD diagnosis in accordance with the Diagnostic and Statistical Manual IV criteria for depression. Clinical information, assessments of stroke severity, and imaging data were recorded on admission. We further detected plasma miR-22 using quantitative PCR and analyzed the relationship among miR-22, clinical data, and PSD using SPSS 23.0 software. Logistic regression showed that deep (OR=1.845, 95%CI: 1.006-3.386, P=0.047) and brain stem CMBs (OR=2.652, 95%CI: 1.110–6.921, P=0.040), as well as plasma miR-22 levels (OR=2.094, 95%CI: 1.066–4.115, P=0.032) were independent risk factors for PSD. In addition, there were significant differences in baseline National Institutes of Health Stroke Scale scores (OR=1.881, 95%CI: 1.180–3.011, P=0.007) and Widowhood scores (OR=1.903, 95%CI: 1.182–3.063, P=0.012). Analysis of the receiver operating curve (AUC=0.723, 95%CI: 0.562–0.883, P=0.016) revealed that miR-22 could predict PSD one month after ischemic stroke. Furthermore, plasma miR-22 levels in brainstem and deep CMBs patients showed an upward trend (P=0.028) relative to the others. Patients with acute ischemic stroke, having brainstem and deep cerebral microbleeds, or a higher plasma miR-22 were more likely to develop PSD. These findings indicate that miR-22 might be involved in cerebral microvascular impairment and post-stroke depression.
DOI: 10.6084/m9.figshare.12210674
title: Expression of CHPF modulates cell proliferation and invasion in lung cancer

description: Lung cancer is the most common malignancy worldwide and is characterized by rapid progression, aggressive behavior, frequent recurrence, and poor prognosis. The TCGA database indicates that chondroitin polymerizing factor (CHPF) is overexpressed in human lung cancer tissues compared with normal tissues and this overexpression corresponds to shorter overall survival in lung cancer patients. In this study, to investigate the function of CHPF in lung cancer, lentiviral vectors expressing CHPF shRNA were stably transduced into A549 and H1299 cells. Compared to shCtrl cells, CHPF knockdown cells had significantly reduced proliferation. Furthermore, the silencing of CHPF in A549 and H1299 cells resulted in apoptotic induction, which led to decreased colony formation. Wound healing and transwell invasion assays revealed that CHPF could positively regulate the migration of lung cancer cells. The tumorigenic role of CHPF was also validated in nude mouse xenograft models. Affymetrix gene chip analysis indicated that CHPF regulated the proliferation and invasion of lung cancer cells through CDH1, RRM2, MKI67, and TNFRSF10B. We thus highlight CHPF as a novel target for lung cancer treatment.
DOI: 10.6084/m9.figshare.13257450
title: Additional file 1 of Transcriptome analysis identifies genes involved in the somatic embryogenesis of Eucalyptus

description: Additional file 1. Gene expression profiles of differentiated and dedifferentiated tissues of E. camaldulensis and E. grandis x urophylla.
DOI: 10.6084/m9.figshare.13257465.v1
title: Additional file 6 of Transcriptome analysis identifies genes involved in the somatic embryogenesis of Eucalyptus

description: Additional file 6. KEGG pathway enriched by the mutated genes specifically identified in E. camaldulensis.
DOI: 10.15468/dl.nu4g6e
title: Occurrence Download

description: A dataset containing 3501 species occurrences available in GBIF matching the query:
{
 "DatasetKey" : [
 "is Fauna y flora asociada al Plan de Manejo Ambiental para el Distrito Regional de Manejo Integrado Mata de la Urama"
 ]
}

 The dataset includes 3501 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0009299-250827131500795/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.