cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.5955929
title: AGEs and sRAGE Variations at Different Timepoints in Patients with Chronic Kidney Disease

description: Dataset from Molinari P, Caldiroli L, Dozio E, Rigolini R, Giubbilini P, Romanelli MMC, Messa P, Vettoretti S. AGEs and sRAGE Variations at Different Timepoints in Patients with Chronic Kidney Disease. Antioxidants (Basel). 2021 Dec 15;10(12):1994. doi: 10.3390/antiox10121994. PMID: 34943097; PMCID: PMC8698924. Abstract Patients with chronic kidney disease (CKD) are affected by enhanced oxidative stress and chronic inflammation, and these factors may contribute to increase advanced glycation end-products (AGEs). In this study we quantified AGEs and soluble receptors for AGE (sRAGE) isoforms and evaluated the association between their variations and eGFR at baseline and after 12 months. We evaluated 64 patients. AGEs were quantified by fluorescence intensity using a fluorescence spectrophotometer, and sRAGE by ELISA. Median age was 81 years, male patients accounted for 70%, 63% were diabetic, and eGFR was 27 ± 10 mL/min/1.73 m<sup>2</sup>. At follow up, sRAGE isoforms underwent a significant decrement (1679 [1393;2038] vs. 1442 [1117;2102], <em>p</em> &lt; 0.0001), while AGEs/sRAGE ratios were increased (1.77 ± 0.92 vs. 2.24 ± 1.34, <em>p</em> = 0.004). Although AGEs and AGEs/sRAGE ratios were inversely related with eGFR, their basal values as well their variations did not show a significant association with eGFR changes. In a cohort of patients with a stable clinical condition at 1 year follow-up, AGEs/sRAGE was associated with renal function. The lack of association with eGFR suggests that other factors can influence its increase. In conclusion, AGEs/sRAGE can be an additional risk factor for CKD progression over a longer time, but its role as a prognostic tool needs further investigation.
DOI: 10.5281/zenodo.5923589
title: Replication Package for: "Overcoming the gap between structured dependencies and change coupling"

description: This datasets contains example projects that resulted from the empirical analysis of the history of object-oriented cyber-physical<br> systems: Glucosio/glucosio-android<sup>[1]</sup> , isl-org/OpenBot<sup>[2]</sup>, eclipse/concierge<sup>[3]</sup>, and WPIRoboticsProjects/GRIP<sup>[4]</sup>. It was created using our prototype tool <em>callgraphCA</em> to discover metrics of software changes, based on<br> call graph analysis and evolution and serve to display change coupling of artifacts and call graph evolution. Contained in the dataset are the databases generated by <em>callgraphCA </em>as well as example Notebooks that show the project results and <em>callgraphCA </em>libraries that support the analysis. For detailed information about <em>callgraphCA </em>visit GitHub: GLopezMUZH/callgraphCA [1] https://github.com/Glucosio/glucosio-android [2] https://github.com/isl-org/OpenBot/ [3] https://github.com/eclipse/concierge [4] https://github.com/WPIRoboticsProjects/GRIP
DOI: 10.5281/zenodo.5923588
title: Replication Package for: "Overcoming the gap between structured dependencies and change coupling"

description: This datasets contains example projects that resulted from the empirical analysis of the history of object-oriented cyber-physical<br> systems: Glucosio/glucosio-android<sup>[1]</sup> , isl-org/OpenBot<sup>[2]</sup>, eclipse/concierge<sup>[3]</sup>, and WPIRoboticsProjects/GRIP<sup>[4]</sup>. It was created using our prototype tool <em>callgraphCA</em> to discover metrics of software changes, based on<br> call graph analysis and evolution and serve to display change coupling of artifacts and call graph evolution. Contained in the dataset are the databases generated by <em>callgraphCA </em>as well as example Notebooks that show the project results and <em>callgraphCA </em>libraries that support the analysis. For detailed information about <em>callgraphCA </em>visit GitHub: GLopezMUZH/callgraphCA [1] https://github.com/Glucosio/glucosio-android [2] https://github.com/isl-org/OpenBot/ [3] https://github.com/eclipse/concierge [4] https://github.com/WPIRoboticsProjects/GRIP
DOI: 10.6084/m9.figshare.19093103
title: Supplementary Materials

description: Supplementary Materials of "In silico protein structure prediction of the whole proteome of <i>Acidithiobacillus ferrooxidans</i> ATCC23270, the model strain of biohydrometallurgy"
DOI: 10.6084/m9.figshare.19093103.v2
title: Supplementary Materials

description: Supplementary Materials of "In silico protein structure prediction of the whole proteome of <i>Acidithiobacillus ferrooxidans</i> ATCC23270, the model strain of biohydrometallurgy"
DOI: 10.6084/m9.figshare.19093103.v1
title: Supplementary Materials

description: Supplementary Materials of "In silico protein structure prediction of the whole proteome of <i>Acidithiobacillus ferrooxidans</i> ATCC23270, the model strain of biohydrometallurgy"
DOI: 10.25505/fiz.icsd.cc256qdj
title: CSD 2002457: Experimental Crystal Structure Determination

description: Related Article: Wenyao Zhang, Zhonglei Wei, Zhihua Yang, Shilie Pan|2020|Dalton Trans.|49|11591|doi:10.1039/D0DT01951H
DOI: 10.5517/ccdc.csd.cc25phx9
title: CCDC 2016671: Experimental Crystal Structure Determination

description: Related Article: A.M. Wheaton, I.A. Guzei, J.F. Berry|2020|Acta Crystallogr.,Sect.E:Cryst.Commun.|76|1336|doi:10.1107/S2056989020009676
DOI: 10.5517/ccdc.csd.cc25phyb
title: CCDC 2016672: Experimental Crystal Structure Determination

description: Related Article: A.M. Wheaton, I.A. Guzei, J.F. Berry|2020|Acta Crystallogr.,Sect.E:Cryst.Commun.|76|1336|doi:10.1107/S2056989020009676
DOI: 10.5517/ccdc.csd.cc25phzc
title: CCDC 2016673: Experimental Crystal Structure Determination

description: Related Article: A.M. Wheaton, I.A. Guzei, J.F. Berry|2020|Acta Crystallogr.,Sect.E:Cryst.Commun.|76|1336|doi:10.1107/S2056989020009676
DOI: 10.5517/ccdc.csd.cc25pj0f
title: CCDC 2016674: Experimental Crystal Structure Determination

description: Related Article: A.M. Wheaton, I.A. Guzei, J.F. Berry|2020|Acta Crystallogr.,Sect.E:Cryst.Commun.|76|1336|doi:10.1107/S2056989020009676
DOI: 10.5517/ccdc.csd.cc25pj1g
title: CCDC 2016675: Experimental Crystal Structure Determination

description: Related Article: A.M. Wheaton, I.A. Guzei, J.F. Berry|2020|Acta Crystallogr.,Sect.E:Cryst.Commun.|76|1336|doi:10.1107/S2056989020009676
DOI: 10.25505/fiz.icsd.cc25c3d2
title: CSD 2006673: Experimental Crystal Structure Determination

description: Related Article: H. Nan, L. Chen, R.-J. Zhang, D. Zhao|2020|Acta Crystallogr.,Sect.C:Cryst.Struct.Chem.|76|771|doi:10.1107/S2053229620009857
DOI: 10.25505/fiz.icsd.cc25rgxb
title: CSD 2018562: Experimental Crystal Structure Determination

description: Related Article: A. Badri, I. Alvarez-Serrano, M. Luisa López, M. Ben Amara|2020|Acta Crystallogr.,Sect.E:Cryst.Commun.|76|1369|doi:10.1107/S2056989020010191
DOI: 10.25505/fiz.icsd.cc258w7l
title: CSD 2004529: Experimental Crystal Structure Determination

description: Related Article: Shu Guo, Kelly M. Powderly, R. J. Cava|2020|Dalton Trans.|49|12018|doi:10.1039/D0DT01836H
DOI: 10.5517/ccdc.csd.cc25ss70
title: CCDC 2019812: Experimental Crystal Structure Determination

description: Related Article: Yan Wang, Tong-Tong Jing, Jia-Ling Zhang, Yu-Ting Liu, Shi-Ping Wang, Qian-Feng Zhang, Pei-Zhi Zhang, Bi-Hai Tong, Shang-Hui Ye, Fu-Quan Bai|2022|Inorg.Chem.Commun.|137|109170|doi:10.1016/j.inoche.2021.109170
DOI: 10.25505/fiz.icsd.cc25sx74
title: CSD 2019936: Experimental Crystal Structure Determination

description: Related Article: G.J. Redhammer, G. Tippelt|2020|Acta Crystallogr.,Sect.E:Cryst.Commun.|76|1412|doi:10.1107/S2056989020010427
DOI: 10.25934/pr00005725.0
title: Available IPD datapackage for study 'A Randomized, Open Label Study to Compare the Complete Pathological Response Rate Achieved With 4 Combinations of Herceptin, Docetaxel and Pertuzumab in Patients With Locally Advanced, Inflammatory or Early Stage HER2 Positive Breast Cancer'

description: This 4 arm study will evaluate the efficacy and safety of 4 neoadjuvant treatment regimens in female patients with locally advanced, inflammatory or early stage HER2 positive breast cancer. Before surgery, patients will be randomized to one of 4 treatment arms, to receive 4 cycles of a)Herceptin + docetaxel b)Herceptin + docetaxel + pertuzumab c)Herceptin + pertuzumab or 4)pertuzumab + docetaxel. Pertuzumab will be administered at a loading dose of 840mg iv, then 420mg iv 3-weekly, Herceptin at a loading dose of 8mg/kg iv then 6mg/kg 3-weekly, and docetaxel at a dose of 75mg/m2 escalating to 100mg/m2 3-weekly. During the entire pre- and post-surgery period all patients will receive adequate chemotherapy as per standard of care, as well as any surgery and/or radiotherapy as required. The anticipated time on study treatment is 3-12 months, and the target sample size is 100-500 individuals.
DOI: 10.5281/zenodo.5911465
title: Thirty minutes identified as the threshold for development of pain in low back and feet regions, and predictors of intensity of pain during 1-hour laboratory-based standing in office workers.

description: This study with 40 office workers investigated a) the effect of time spent standing on low back and lower limb pain during 1-hour laboratory-based task; b) the minutes after which significant increase in pain are likely; and c) which individual, physical and psychosocial factors predicted pain. The primary outcome was bodily location of pain and intensity on a 100mm Visual Analogue Scale recorded at baseline and every 15 minutes. Measurements included trunk and hip motor control and endurance. Self-report history of pain, physical activity, psychosocial job characteristics, pain catastrophizing and general health status were collected. Univariate analysis and regression models were included. The prevalence of low back pain more than doubled to 40% after 30’ while feet pain increased to 25% from 0 at baseline. The intensity of low back and lower limb pain also increased over time. Thirty minutes was identified as the threshold for the development and increase in low back and feet pain. Modifiable factors were associated with low back pain intensity - lower hip abductor muscle endurance and poorer physical health and with feet symptoms - greater body mass index and less core stability
DOI: 10.5281/zenodo.4422085
title: Genome assemblies of the sugarcane orange rust fungal pathogen Puccinia kuehnii

description: <em>Puccinia kuehnii</em>is an obligate biotrophic fungal pathogen that causes orange rust of sugarcane, which is prevalent in many countries around the globe. In the USA, orange rust was first detected in sugarcane in Florida in 2007 and poses a persistent and economically damaging threat to the sugarcane industry in this region. Here, we generated the first genome assemblies for two isolates of <em>P. kuehnii </em>(1040 and 2143) collected in Florida in 2017 from two sugarcane cultivars, CL85-1040 and CP89-2143, respectively. These two rust genome resources will be of immense value for future genomic studies, particularly further exploration of the predicted secretomes that may help define key pathogenicity determinants for this economically important pathogen.
DOI: 10.5281/zenodo.4422084
title: Genome assemblies of the sugarcane orange rust fungal pathogen Puccinia kuehnii

description: <em>Puccinia kuehnii</em>is an obligate biotrophic fungal pathogen that causes orange rust of sugarcane, which is prevalent in many countries around the globe. In the USA, orange rust was first detected in sugarcane in Florida in 2007 and poses a persistent and economically damaging threat to the sugarcane industry in this region. Here, we generated the first genome assemblies for two isolates of <em>P. kuehnii </em>(1040 and 2143) collected in Florida in 2017 from two sugarcane cultivars, CL85-1040 and CP89-2143, respectively. These two rust genome resources will be of immense value for future genomic studies, particularly further exploration of the predicted secretomes that may help define key pathogenicity determinants for this economically important pathogen.
DOI: 10.6084/m9.figshare.19114325
title: Supplementary Material for: Evaluation of the Autoimmunity and Preexisting Risky Conditions for Hypersensitivity Reactions to COVID-19 Vaccines

description: <b><i>Introduction:</i></b> The role of autoimmunity and other preexisting risky conditions in hypersensitivity reactions (HSRs) to COVID-19 vaccines seems unclear. The aim of the study was to investigate the autoimmunity and preexisting risky conditions in HSRs to COVID-19 vaccines. <b><i>Methods:</i></b> The patients aged ≥18 years with a history of HSR to CoronaVac or Pfizer-BioNTech COVID-19 vaccines within 24 h in 2 tertiary centers were assessed. The patients were divided according to the type of vaccine which they showed immediate-type (&lt;4 h) HSR to (group A1 for CoronaVac and group B1 for Pfizer-BioNTech). Equal number of subjects who did not show HSR to two doses of either CoronaVac or Pfizer-BioNTech was recruited into the study as control groups (group A2 for CoronaVac and group B2 for Pfizer-BioNTech). The autologous serum skin test (ASST) was performed on patient and control groups. Later, the demographic, clinical, and laboratory features were compared between groups. <b><i>Results:</i></b> A total number of 27 patients were included in the study. Subjects with chronic spontaneous urticaria (CSU) were more frequent in group B1 than in group B2 (<i>p</i>:0.041). In addition to CSU, the presence of HSRs to drugs was higher in group A1 than in A2 (both <i>p</i>:0.007). The presence of autoimmunity and autoimmune diseases, positivity of antithyroid peroxidase antibody, and ASST were less in group A2 than in A1 (<i>p</i>:0.015, <i>p</i>:0.048, <i>p</i>:0.048, and <i>p</i>:0.037). Additionally, COVID-19 infection history was less in group A2 than in A1 (<i>p</i>:0.037). <b><i>Discussion/Conclusion:</i></b> Type IIb autoimmunity seems to play a role in immediate type HSRs to the CoronaVac vaccine as previously shown in autoimmune CSU and multidrug hypersensitivity.
DOI: 10.5281/zenodo.5956425
title: Hydrogen isotope data of DN-1 core

description: Exploring the processes involved with hydroclimate changes during the Mystery Interval (MI) will enhance understanding of the global climate system. The associated mechanism of seasonal variations of rainfall in the East Asian Summer Monsoon (EASM) region during the MI remains poorly known. Here we show that the δ<sup>2</sup>H values of leaf wax <em>n</em>-alkanes (δ<sup>2</sup>H<sub>alk</sub>) in a wetland core retrieved from southern China remain relatively negative during the MI. Considering the primary synthesis time of leaf waxes in deciduous woody plants and the seasonal variations of precipitation δ<sup>2</sup>H in the EASM, we interpret the low δ<sup>2</sup>H<sub>alk</sub> as the early onset of summer rainfall during the MI. The early onset of summer rainfall was likely due to the early northeastward shifting of the Western Pacific subtropical high as the result of the low land-sea thermogradient between the Qinghai-Tibet Plateau and West Pacific Ocean during late-spring to early-summer.
DOI: 10.5281/zenodo.5956424
title: Hydrogen isotope data of DN-1 core

description: Exploring the processes involved with hydroclimate changes during the Mystery Interval (MI) will enhance understanding of the global climate system. The associated mechanism of seasonal variations of rainfall in the East Asian Summer Monsoon (EASM) region during the MI remains poorly known. Here we show that the δ<sup>2</sup>H values of leaf wax <em>n</em>-alkanes (δ<sup>2</sup>H<sub>alk</sub>) in a wetland core retrieved from southern China remain relatively negative during the MI. Considering the primary synthesis time of leaf waxes in deciduous woody plants and the seasonal variations of precipitation δ<sup>2</sup>H in the EASM, we interpret the low δ<sup>2</sup>H<sub>alk</sub> as the early onset of summer rainfall during the MI. The early onset of summer rainfall was likely due to the early northeastward shifting of the Western Pacific subtropical high as the result of the low land-sea thermogradient between the Qinghai-Tibet Plateau and West Pacific Ocean during late-spring to early-summer.
DOI: 10.5281/zenodo.5956073
title: Antibody responses to BNT162b2 mRNA vaccine: infection-naïve individuals with abdominal obesity warrant attention.

description: Dataset from Malavazos AE, Basilico S, Iacobellis G, Milani V, Cardani R, Boniardi F, Dubini C, Prandoni I, Capitanio G, Renna LV, Boveri S, Rigolini R, Carrara M, Spuria G, Cuppone T, D'acquisto A, Carpinelli L, Sacchi M, Morricone L, Secchi F, Costa E, Menicanti L, Nisoli E, Carruba M, Ambrogi F, Corsi Romanelli MM. Antibody responses to BNT162b2 mRNA vaccine: infection-naïve individuals with abdominal obesity warrant attention. Obesity (Silver Spring). 2021 Nov 30. doi: 10.1002/oby.23353. Epub ahead of print. PMID: 34850576. Abstract <strong>Objective: </strong>The excess of visceral adipose tissue might hinder and delay immune response. How people with abdominal obesity (AO) will respond to mRNA vaccines against SARS-CoV-2 is yet to be established. We evaluated SARS-CoV-2 specific antibody responses after the first and second dose of the BNT162b2 mRNA vaccine comparing the response of individuals with AO to those without, discerning between individuals with or without prior infection. <strong>Methods: </strong>IgG neutralizing antibodies against the Trimeric-complex (IgG-TrimericS) were measured at four time points: at baseline, at day 21 after vaccine dose 1, at one and three months after dose 2. Nucleocapsid antibodies were assessed to detect prior SARS-CoV-2 infection. Waist circumference was measured to determine AO. <strong>Results: </strong>Between the first and third month after vaccine dose 2, the drop in IgG-TrimericS levels was more remarkable in individuals with AO compared to those without AO (2.44 fold [95%CI: 2.22-2.63] vs 1.82 fold [95%CI: 1.69-1.92], respectively, p&lt;0.001). Multivariable linear regression confirmed this result after inclusion of assessed confounders (p&lt;0.001). <strong>Conclusions: </strong>The waning antibody levels in individuals with AO may further support recent recommendations to offer booster vaccines to adults with high-risk medical conditions including obesity and particularly to those with more prevalent abdominal obesity phenotype.
DOI: 10.5281/zenodo.5956072
title: Antibody responses to BNT162b2 mRNA vaccine: infection-naïve individuals with abdominal obesity warrant attention.

description: Dataset from Malavazos AE, Basilico S, Iacobellis G, Milani V, Cardani R, Boniardi F, Dubini C, Prandoni I, Capitanio G, Renna LV, Boveri S, Rigolini R, Carrara M, Spuria G, Cuppone T, D'acquisto A, Carpinelli L, Sacchi M, Morricone L, Secchi F, Costa E, Menicanti L, Nisoli E, Carruba M, Ambrogi F, Corsi Romanelli MM. Antibody responses to BNT162b2 mRNA vaccine: infection-naïve individuals with abdominal obesity warrant attention. Obesity (Silver Spring). 2021 Nov 30. doi: 10.1002/oby.23353. Epub ahead of print. PMID: 34850576. Abstract <strong>Objective: </strong>The excess of visceral adipose tissue might hinder and delay immune response. How people with abdominal obesity (AO) will respond to mRNA vaccines against SARS-CoV-2 is yet to be established. We evaluated SARS-CoV-2 specific antibody responses after the first and second dose of the BNT162b2 mRNA vaccine comparing the response of individuals with AO to those without, discerning between individuals with or without prior infection. <strong>Methods: </strong>IgG neutralizing antibodies against the Trimeric-complex (IgG-TrimericS) were measured at four time points: at baseline, at day 21 after vaccine dose 1, at one and three months after dose 2. Nucleocapsid antibodies were assessed to detect prior SARS-CoV-2 infection. Waist circumference was measured to determine AO. <strong>Results: </strong>Between the first and third month after vaccine dose 2, the drop in IgG-TrimericS levels was more remarkable in individuals with AO compared to those without AO (2.44 fold [95%CI: 2.22-2.63] vs 1.82 fold [95%CI: 1.69-1.92], respectively, p&lt;0.001). Multivariable linear regression confirmed this result after inclusion of assessed confounders (p&lt;0.001). <strong>Conclusions: </strong>The waning antibody levels in individuals with AO may further support recent recommendations to offer booster vaccines to adults with high-risk medical conditions including obesity and particularly to those with more prevalent abdominal obesity phenotype.
DOI: 10.48370/ofd/eglcei/soebel
title: Lasiobelonium nidulum (J. C. Schmidt & Kunze) Spooner F-1688.jpg

description: :unav
DOI: 10.48370/ofd/eglcei/cxqkkz
title: Lasiobelonium nidulum (J. C. Schmidt & Kunze) Spooner F-1688 (2).jpg

description: :unav
DOI: 10.48370/ofd/eglcei/9azsnu
title: Lasiobelonium nidulum (J. C. Schmidt & Kunze) Spooner F-1688.tif

description: :unav
DOI: 10.48370/ofd/eglcei/8gzxk8
title: Lasiobelonium nidulum (J. C. Schmidt & Kunze) Spooner F-1688 (3).JPG

description: :unav
DOI: 10.48370/ofd/eglcei
title: Lasiobelonium nidulum (J. C. Schmidt Kunze) Spooner, 1688

description: Fungarium Mikromycetes
DOI: 10.48370/ofd/usunxc/mzp8db
title: Lasiobelonium nidulum (J. C. Schmidt & Kunze) Spooner F-1545.tif

description: :unav
DOI: 10.48370/ofd/usunxc
title: Lasiobelonium nidulum (J. C. Schmidt Kunze) Spooner, 1545

description: Fungarium Mikromycetes
DOI: 10.5281/zenodo.5956512
title: Experiences of healthcare providers from a working week during the first wave of the COVID-19 outbreak

description: Dataset from Villa G, Dellafiore F, Caruso R, Arrigoni C, Galli E, Moranda D, Prampolini L, Bascape B, Merlo MG, Giannetta N, Manara DF. Experiences of healthcare providers from a working week during the first wave of the COVID-19 outbreak. Acta Biomed. 2021 Oct 5;92(S6):e2021458. doi: 10.23750/abm.v92iS6.12311. PMID: 34739456. Abstract <strong>Background and aim of the work: </strong>The delivery of care to patients with COVID-19 enhanced many psychological issues among healthcare workers (HCWs), exacerbating the risk of burnout and compromising the efficacy and quality of services provided to patients. In this context, the peculiarities regarding professional roles in delivering care to patients with COVID-19 might reflect daily lived experiences that could impact psychological outcomes in specific professional groups. However, daily lived experiences considering different groups of HCWs have been poorly investigated, especially with a longitudinal qualitative study. Accordingly, our study aims firstly to longitudinally explore perceptions and experiences of HCWs about their daily working life during the initial COVID-19 outbreak, highlighting the specific lived experiences of physicians, nurses, radiology technicians, and healthcare assistants. <strong>Methods: </strong>A longitudinal qualitative content analysis was conducted to analyse the comments and quotations made on a daily diary lasting seven days by physicians, nurses, radiology technicians, and healthcare assistants during the first wave of the COVID-19 outbreak. According to Elo and Kyngäs recommendation, the data analysis process was developed in three main phases: preparation, organising, and reporting. <strong>Results: </strong>Four main generic categories emerged by data analysis: 'Clinical practice in COVID-19 patients'; 'The importance of relationship'; 'Navigating by sight'; and 'Good always pays off'. Several differences emerged from the sentences of the HCWs, which require further investigation.