cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.30425629.v1
title: Supplementary Material for: Target based biofilm inhibition and antibiotic enhancement strategy by miR.101.3p using DNA tetrahedrons

description: Cystic Fibrosis is an inherited disease caused by mutations in the CF transmembrane conductance regulator gene. It is characterized by progressive decline in lung function, often driven by chronic respiratory infections, particularly with Staphylococcus aureus and Pseudomonas aeruginosa. MicroRNAs, small, non-coding RNAs that negatively regulate protein expression by binding to mRNA, are altered in people with CF, and contribute to the pulmonary manifestations of CF. The management of CF lung infections is complicated by the formation of bacterial biofilms and antimicrobial resistance. In silico analysis identified hsa.miR.101.3p as a miRNA potentially targeting genes associated with β-lactam resistance and biofilm formation in P. aeruginosa, as well as genes involved in the overall growth of S. aureus. To facilitate delivery, miRNA-mimic DNA oligonucleotides were conjugated to DNA tetrahedrons. The structural integrity of the DNAtd-miRNA complexes was confirmed via transmission electron microscopy, characterized by nanoparticle tracking analysis, and successful bacterial uptake was verified using fluorescence microscopy. DNAtd-miR.101.3p significantly reduced the viability of S. aureus and P. aeruginosa. DNAtd-miR-101-3p enhanced the activity of the beta-lactam antibiotic cefotaxime against planktonic and biofilm-forming P. aeruginosa. The mechanisms involve DNAtd-miR.101.3p targeting of ampC, fleN and pslK. MiR.101.3p, which is expressed in CF bronchial epithelial cells, displays unique inhibition properties against P. aeruginosa and S. aureus in vitro and increases the rate of the bactericidal activity of cefotaxime against P. aeruginosa.
DOI: 10.5517/cc1j45ys
title: CCDC 1404205: Experimental Crystal Structure Determination

description: Related Article: Muhammad Farooq Ibad ,  Axel Schulz,  Alexander Villinger|2015|Organometallics|34|3893|doi:10.1021/acs.organomet.5b00492
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc1j45zt
title: CCDC 1404206: Experimental Crystal Structure Determination

description: Related Article: Muhammad Farooq Ibad ,  Axel Schulz,  Alexander Villinger|2015|Organometallics|34|3893|doi:10.1021/acs.organomet.5b00492
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc137fj9
title: CCDC 1020040: Experimental Crystal Structure Determination

description: Related Article: A. Carletta, A. Tilborg, L. Moineaux, J. de Ruyck, L. Basile, L. Salerno, G. Romeo, J. Wouters, S. Guccione|2015|Acta Crystallogr.,Sect.B:Struct.Sci.,Cryst.Eng. and Mat.|71|447|doi:10.1107/S2052520615010410
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc1j460w
title: CCDC 1404207: Experimental Crystal Structure Determination

description: Related Article: Muhammad Farooq Ibad ,  Axel Schulz,  Alexander Villinger|2015|Organometallics|34|3893|doi:10.1021/acs.organomet.5b00492
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc137fkb
title: CCDC 1020041: Experimental Crystal Structure Determination

description: Related Article: A. Carletta, A. Tilborg, L. Moineaux, J. de Ruyck, L. Basile, L. Salerno, G. Romeo, J. Wouters, S. Guccione|2015|Acta Crystallogr.,Sect.B:Struct.Sci.,Cryst.Eng. and Mat.|71|447|doi:10.1107/S2052520615010410
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc137flc
title: CCDC 1020042: Experimental Crystal Structure Determination

description: Related Article: A. Carletta, A. Tilborg, L. Moineaux, J. de Ruyck, L. Basile, L. Salerno, G. Romeo, J. Wouters, S. Guccione|2015|Acta Crystallogr.,Sect.B:Struct.Sci.,Cryst.Eng. and Mat.|71|447|doi:10.1107/S2052520615010410
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc137fmd
title: CCDC 1020043: Experimental Crystal Structure Determination

description: Related Article: A. Carletta, A. Tilborg, L. Moineaux, J. de Ruyck, L. Basile, L. Salerno, G. Romeo, J. Wouters, S. Guccione|2015|Acta Crystallogr.,Sect.B:Struct.Sci.,Cryst.Eng. and Mat.|71|447|doi:10.1107/S2052520615010410
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc137fnf
title: CCDC 1020044: Experimental Crystal Structure Determination

description: Related Article: A. Carletta, A. Tilborg, L. Moineaux, J. de Ruyck, L. Basile, L. Salerno, G. Romeo, J. Wouters, S. Guccione|2015|Acta Crystallogr.,Sect.B:Struct.Sci.,Cryst.Eng. and Mat.|71|447|doi:10.1107/S2052520615010410
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc1j43f6
title: CCDC 1404127: Experimental Crystal Structure Determination

description: Related Article: R. G. Waruna Jinadasa, Yuanyuan Fang, Siddhartha Kumar, Allen J. Osinski, Xiaoqin Jiang, Christopher J. Ziegler, Karl M. Kadish, Hong Wang|2015|J.Org.Chem.|80|12076|doi:10.1021/acs.joc.5b01906
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc1j43g7
title: CCDC 1404128: Experimental Crystal Structure Determination

description: Related Article: Liu Liu, David A. Ruiz, Fatme Dahcheh, Guy Bertrand, Riccardo Suter, Aaron M. Tondreau, Hansjörg Grützmacher|2016|Chemical Science|7|2335|doi:10.1039/C5SC04504E
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc1j43h8
title: CCDC 1404129: Experimental Crystal Structure Determination

description: Related Article: Liu Liu, David A. Ruiz, Fatme Dahcheh, Guy Bertrand, Riccardo Suter, Aaron M. Tondreau, Hansjörg Grützmacher|2016|Chemical Science|7|2335|doi:10.1039/C5SC04504E
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc1j43j9
title: CCDC 1404130: Experimental Crystal Structure Determination

description: Related Article: Liu Liu, David A. Ruiz, Fatme Dahcheh, Guy Bertrand, Riccardo Suter, Aaron M. Tondreau, Hansjörg Grützmacher|2016|Chemical Science|7|2335|doi:10.1039/C5SC04504E
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc1j43kb
title: CCDC 1404131: Experimental Crystal Structure Determination

description: Related Article: Liu Liu, David A. Ruiz, Fatme Dahcheh, Guy Bertrand, Riccardo Suter, Aaron M. Tondreau, Hansjörg Grützmacher|2016|Chemical Science|7|2335|doi:10.1039/C5SC04504E
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc1j43lc
title: CCDC 1404132: Experimental Crystal Structure Determination

description: Related Article: Liu Liu, David A. Ruiz, Fatme Dahcheh, Guy Bertrand, Riccardo Suter, Aaron M. Tondreau, Hansjörg Grützmacher|2016|Chemical Science|7|2335|doi:10.1039/C5SC04504E
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc1j43md
title: CCDC 1404133: Experimental Crystal Structure Determination

description: Related Article: Liu Liu, David A. Ruiz, Fatme Dahcheh, Guy Bertrand, Riccardo Suter, Aaron M. Tondreau, Hansjörg Grützmacher|2016|Chemical Science|7|2335|doi:10.1039/C5SC04504E
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc1j43nf
title: CCDC 1404134: Experimental Crystal Structure Determination

description: Related Article: Liu Liu, David A. Ruiz, Fatme Dahcheh, Guy Bertrand, Riccardo Suter, Aaron M. Tondreau, Hansjörg Grützmacher|2016|Chemical Science|7|2335|doi:10.1039/C5SC04504E
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc1j43pg
title: CCDC 1404135: Experimental Crystal Structure Determination

description: Related Article: Liu Liu, David A. Ruiz, Fatme Dahcheh, Guy Bertrand, Riccardo Suter, Aaron M. Tondreau, Hansjörg Grützmacher|2016|Chemical Science|7|2335|doi:10.1039/C5SC04504E
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc1j3zg2
title: CCDC 1404004: Experimental Crystal Structure Determination

description: Related Article: T.C.M. Noguiera, A.C. Pinheiro, J.L. Wardell, M.V.N. de Souza, J.P. Abberley, W.T.A. Harrison|2015|Acta Crystallogr.,Sect.E:Cryst.Commun.|71|752|doi:10.1107/S2056989015010440
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc1j3zh3
title: CCDC 1404005: Experimental Crystal Structure Determination

description: Related Article: T.C.M. Noguiera, A.C. Pinheiro, J.L. Wardell, M.V.N. de Souza, J.P. Abberley, W.T.A. Harrison|2015|Acta Crystallogr.,Sect.E:Cryst.Commun.|71|752|doi:10.1107/S2056989015010440
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc1j3zj4
title: CCDC 1404006: Experimental Crystal Structure Determination

description: Related Article: T.C.M. Noguiera, A.C. Pinheiro, J.L. Wardell, M.V.N. de Souza, J.P. Abberley, W.T.A. Harrison|2015|Acta Crystallogr.,Sect.E:Cryst.Commun.|71|752|doi:10.1107/S2056989015010440
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc1j43qh
title: CCDC 1404136: Experimental Crystal Structure Determination

description: Related Article: Mashooq Ahmad Bhat, Abdul Arif Khan, Hazem A Ghabbour, Ching Kheng Quah, Hoong-Kun Fun|2016|Trop.J.Pharm.Res.|15|1751|doi:10.4314/tjpr.v15i8.22
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc1j40rf
title: CCDC 1404044: Experimental Crystal Structure Determination

description: Related Article: Wei Zhu, Chen Wang, Yue Lan, Jian Li, Hui Wang, Ning Gao, Jingwei Ji, Guangtao Li|2016|Langmuir|32|9045|doi:10.1021/acs.langmuir.6b02365
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc1j42b2
title: CCDC 1404093: Experimental Crystal Structure Determination

description: Related Article: Wei Zhu, Chen Wang, Yue Lan, Jian Li, Hui Wang, Ning Gao, Jingwei Ji, Guangtao Li|2016|Langmuir|32|9045|doi:10.1021/acs.langmuir.6b02365
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc1j3zn8
title: CCDC 1404010: Experimental Crystal Structure Determination

description: Related Article: Erin L. Dodd, D. Scott Bohle|2016|Polyhedron|108|36|doi:10.1016/j.poly.2015.07.072
description: Related Article: D. Scott Bohle, Erin Dodd|2015|CSD Communication|||
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc14hmjs
title: CCDC 1057705: Experimental Crystal Structure Determination

description: Related Article: Xin-Xin Lu, Yu-Hui Luo, Chen Lu, Xin Chen, Hong Zhang|2015|J.Solid State Chem.|232|123|doi:10.1016/j.jssc.2015.09.017
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc1j43tl
title: CCDC 1404139: Experimental Crystal Structure Determination

description: Related Article: Erin L. Dodd, D. Scott Bohle|2016|Polyhedron|108|36|doi:10.1016/j.poly.2015.07.072
description: Related Article: D. Scott Bohle, Erin Dodd|2015|CSD Communication|||
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc1j3ztf
title: CCDC 1404015: Experimental Crystal Structure Determination

description: Related Article: Yasuo Tanaka, Tomoki Yoneda, Ko Furukawa, Taro Koide, Hirotaka Mori, Takayuki Tanaka, Hiroshi Shinokubo, Atsuhiro Osuka|2015|Angew.Chem.,Int.Ed.|54|10908|doi:10.1002/anie.201505130
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc1j3zvg
title: CCDC 1404016: Experimental Crystal Structure Determination

description: Related Article: Yasuo Tanaka, Tomoki Yoneda, Ko Furukawa, Taro Koide, Hirotaka Mori, Takayuki Tanaka, Hiroshi Shinokubo, Atsuhiro Osuka|2015|Angew.Chem.,Int.Ed.|54|10908|doi:10.1002/anie.201505130
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc1j3zwh
title: CCDC 1404017: Experimental Crystal Structure Determination

description: Related Article: Yasuo Tanaka, Tomoki Yoneda, Ko Furukawa, Taro Koide, Hirotaka Mori, Takayuki Tanaka, Hiroshi Shinokubo, Atsuhiro Osuka|2015|Angew.Chem.,Int.Ed.|54|10908|doi:10.1002/anie.201505130
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc1j401q
title: CCDC 1404022: Experimental Crystal Structure Determination

description: Related Article: Hao Wang, Jiji Zhang, Zhenyang Lin, Zuowei Xie|2015|Chem.Commun.|51|16817|doi:10.1039/C5CC06818E
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc1j402r
title: CCDC 1404023: Experimental Crystal Structure Determination

description: Related Article: Hao Wang, Jiji Zhang, Zhenyang Lin, Zuowei Xie|2015|Chem.Commun.|51|16817|doi:10.1039/C5CC06818E
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc1j403s
title: CCDC 1404024: Experimental Crystal Structure Determination

description: Related Article: Hao Wang, Jiji Zhang, Zhenyang Lin, Zuowei Xie|2015|Chem.Commun.|51|16817|doi:10.1039/C5CC06818E
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc1j404t
title: CCDC 1404025: Experimental Crystal Structure Determination

description: Related Article: Hao Wang, Jiji Zhang, Zhenyang Lin, Zuowei Xie|2015|Chem.Commun.|51|16817|doi:10.1039/C5CC06818E
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc1j405v
title: CCDC 1404026: Experimental Crystal Structure Determination

description: Related Article: Min Ren, Zhong-Li Xu, Song-Song Bao, Ting-Ting Wang, Ze-Hua Zheng, Rute A. S. Ferreira, Li-Min Zheng, Luis D. Carlos|2016|Dalton Trans.|45|2974|doi:10.1039/C5DT03897A
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.