cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17632/ttgdhfm4gf.1
title: Immunogenicity and vaccine efficacy of Actinobacillus pleuropneumoniae-derived extracellular vesicles as a novel vaccine candidate

description: Actinobacillus pleuropneumoniae (APP) is a significant pathogen in the swine industry, leading to substantial economic losses and highlighting the need for effective vaccines. This study evaluates the potential of APP-derived extracellular vesicles (APP-EVs) as a vaccine candidate compared to the commercial Coglapix vaccine. APP-EVs, isolated using tangential flow filtration (TFF) and cushioned ultracentrifugation, exhibited an average size of 105 nm and a zeta potential of -17.4 mV. These EVs demonstrated high stability under external stressors, such as pH changes and enzymatic exposure and were found to contain 86 major metabolites. Additionally, APP-EVs induced dendritic cell (DC) maturation in a Toll-like receptor 4 (TLR4)-dependent manner without cytotoxicity. APP-EVs predominantly elicited Th1-mediated IgG responses in immunized mice without significant liver and kidney toxicity. Contrarily, unlike Coglapix, which induced stronger Th2-mediated responses and notable toxicity. In addition, APP-EVs triggered robust APP-specific Th1, Th17, and cytotoxic T lymphocyte (CTL) responses and promoted the activation of multifunctional T-cells. Notably, APP-EV immunization enhanced macrophage phagocytosis and improved survival rates in mice challenged with APP infection compared to those treated with Coglapix. These findings suggest that APP-EVs are promising vaccine candidates, capable of inducing potent APP-specific T-cell responses, particularly Th1, Th17, CTL, and multifunctional T-cells, thereby enhancing the protective immune response against APP infection.
DOI: 10.17632/tkk5pdswty.3
title: Minimizing the Cost of Leveraging Influencers in Social Networks: IP and CP Approaches - Complementary Data

description: This dataset contains complementary data to the paper "Minimizing the Cost of Leveraging Influencers in Social Networks: IP and CP Approaches" [1], which studies integer/constraint programming formulations for the Least Cost Directed Perfect Awareness Problem, an NP-hard optimization problem that arises in the context of influence marketing. Regarding the computational experiments conducted in the paper, we make available:

- Two sets of instances;
- The best known attained solutions;
- The source code;
- An appendix with additional details about the results.

The first input set includes 300 synthetic instances composed of graphs that resemble real-world social networks [2]. The second set consists of 14 instances built from online interactions crawled from X (formerly known as Twitter) [3].

The directories "synthetic_instances" and "x_instances" contain files that describe both sets of instances. The first two lines of each file contain:




where and are the number of vertices and edges in the graph. Each of the next lines contains:

 

where identifies a vertex while and are the cost and threshold associated to that vertex. Each of the remaining lines contains:

 

where and identify an ordered pair of vertices that determines a directed edge with weight .

The directories "solutions_for_synthetic_instances" and "solutions_for_x_instances" contain files that describe the best known solutions for both sets of instances. The first line of each file contains:



where is the number of vertices in the solution. Each of the next lines contains:



where identifies a seed vertex. The last line contains:



where is the solution cost.

The directory "source_code" contains the implementations of the mathematical models studied in the paper.

Lastly, the file "appendix.pdf" presents details of the results reported in the paper [1].

This work was supported by grants from Santander Bank, Brazil, Brazilian National Council for Scientific and Technological Development (CNPq), Brazil, and São Paulo Research Foundation (FAPESP), Brazil.

Caveat: the opinions, hypotheses and conclusions or recommendations expressed in this material are the responsibility of the authors and do not necessarily reflect the views of Santander, CNPq or FAPESP.


References

[1] F. C. Pereira, P. J. de Rezende and T. Yunes. Minimizing the Cost of Leveraging Influencers in Social Networks: IP and CP Approaches. Submitted. 2023.

[2] F. C. Pereira, P. J. de Rezende. The Least Cost Directed Perfect Awareness Problem: complexity, algorithms and computations. Online Social Networks and Media, 37-38, 2023.

[3] C. Schweimer, C. Gfrerer, F. Lugstein, D. Pape, J. A. Velimsky, R. Elsässer, and B. C. Geiger. Generating simple directed social network graphs for information spreading. In Proceedings of the ACM Web Conference 2022, WWW ’22, pages 1475–1485, 2022.
DOI: 10.17632/jmh7w2xdm3.2
title: Myers et al., NrnB

description: Data for "Bacillus subtilis NrnB is expressed during sporulation and acts as a unique 3’-5’ exonuclease" 

All cells employ a combination of endo- and exoribonucleases to degrade long RNA polymers to fragments 2-5 nucleotides in length. These short RNA fragments are processed to monoribonucleotides by nanoRNases. Genetic depletion of nanoRNases has been shown to increase abundance of short RNAs. This deleteriously affects viability, virulence, and fitness, indicating that short RNAs are a metabolic burden. Previously, we provided evidence that NrnA is the housekeeping nanoRNase for Bacillus subtilis. Herein, we investigate the biological and biochemical functions of the evolutionarily related protein, B. subtilis NrnB (NrnBBs). These experiments show that NrnB is surprisingly different from NrnA. While NrnA acts at the 5’ terminus of RNA substrates, NrnB acts at the 3’ terminus. Additionally, NrnA is expressed constitutively under standard growth conditions, yet NrnB is selectively expressed during endospore formation. Furthermore, NrnA processes only short RNAs, while NrnB unexpectedly processes both short RNAs and longer RNAs. Indeed, inducible expression of NrnB can even complement the loss of the known global 3’-5’ exoribonucleases, indicating that it acts as a general exonuclease. Together, these data demonstrate that NrnB proteins, which are widely found in Firmicutes, Epsilonproteobacteria and Archaea, are fundamentally different than NrnA proteins and may be used for specialized purposes.
DOI: 10.17632/xmvb7d23py.1
title: Molecular Epidemiology and Genetic Profile of Non-Typhoidal Salmonella Serovars Isolated from Poultry Production Chain in Khorasan Province, Iran: A Comprehensive Analysis of Prevalence, Virulence Genes, and Antibiotic Resistance

description: Research, Statistics and PCR setup data
DOI: 10.17632/m3x5pck2yz.1
title: LDHU3_09.0970

description: Oligopeptidase b | Serine peptidase Clan SC Family S9A; Leishmania donovani (HU3 strain)
DOI: 10.17632/4377wmc83p.1
title: SOCIO-ECONOMIC FACTORS INFLUENCING SMALLHOLDER VEGETABLE FARMERS TO COMMERCIALISE

description: Socio-economic factors such as access to markets, land ownership, education level, and financial resources significantly influence smallholder farmers' decisions to commercialise vegetable production in the Alfred Nzo and O.R. Tambo District Municipalities. This data suggests that factors related to a farmer's social and economic circumstances play a crucial role in determining whether they choose to engage in commercial vegetable farming. The data analysis focused on the decision to commercialise and market as the central variable, and used both categorical (e.g., education level, marketing channel) and continuous variables (e.g., age, land size), a variety of statistical techniques could be used to examine the relationships between these factors.

For categorical variables like education level and marketing channel, a chi-square test can be used to determine if there is a significant association between these factors and the decision to commercialise. If the dependent variable (decision to commercialise) is binary (e.g., yes/no), logistic regression can be used to model the probability of commercialisation as a function of both categorical and continuous predictors. In dependent variable that is continuous (e.g., level of commercialisation), multiple linear regression can be used to examine how various factors, including categorical and continuous variables, influence the level of commercialisation. ANOVA can be used to compare the means of a continuous dependent variable (e.g., level of commercialisation) across different categories of a categorical predictor (e.g., education level, marketing channel). Therefore, researchers can identify which socio-economic factors are most strongly associated with the decision to commercialise and the level of commercialisation. This information can be used to develop targeted interventions and policies to support smallholder farmers in their commercialisation efforts. It is important to consider potential interaction effects between different variables. For example, the impact of education level on commercialisation might be different for farmers with different levels of land ownership. Researchers may also need to control for other factors that could influence commercialisation decisions, such as access to credit, agricultural extension services, and infrastructure.
DOI: 10.17632/6d4h6x87nb.1
title: Supporting data for: Ecological predictors of mosquito population and arbovirus transmission synchrony estimates

description: We examined seasonal mosquito and arbovirus surveillance data collected in Connecticut, United States from 2001 – 2020 to quantify spatial relationships in 19 mosquito species and 7 arboviruses time series while accounting for environmental factors such as climate and land cover characteristics as well as Euclidean distance. We determined that mosquito collections, on average, were significantly correlated up to 10 km though highly variable among the examined species. Few arboviruses displayed any synchrony and significant maximum correlated distances never exceeded 5 km. After accounting for distance, mixed effects models showed that mosquito or arbovirus identity explained more variance in synchrony estimates than climate or land cover factors. Correlated mosquito collections up to 10 – 20 km suggest that mosquito control operations for nuisance and disease vectors alike must expand treatment zones to regional scales for operations to have population-level impacts. Species identity matters as well, and some mosquito species will require much larger treatment zones than others. The much shorter correlated detection distances for arboviruses reinforce the notion that focal-level processes drive vector-borne pathogen transmission dynamics and risk of spillover into human populations. 

Specific metadata files and underlying data are supplied in this archive and methods needed to reproduce the results are detailed in the manuscript. In brief, the .csv files beginning with "Yr..." contain the annual, effort-corrected collections for either mosquito species or arboviruses collected in either ground-level, CO2-baited CDC light traps or ground-level CDC gravid traps at 87 surveillance sites in Connecticut, U.S. The .csv file beginning with "Coordinates.." contains the latitude and longitude coordinates (in decimal degrees) for each of the 87 surveillance sites. The file named "Mmetadata_Upload) contains brief explanations of each .csv file. Users will need a working knowledge of programming in R in order to replicate any and all methods and results presented in the manuscript.
DOI: 10.17632/4t72h9b4dx.1
title: Data of the study Bioelectrical impedance skin as indicator of thermal sensation.

description: This study aims to accurately present the bioelectrical impedance (BI) as a significant physiological variable to accurately determine thermoregulation and complement thermal sensation questionnaires. A series of
environmental chamber tests were conducted. At the same time, the indoor temperature fluctuated between 20◦C and 40◦C, skin BI of the body area was measured in conjunction with skin temperature and comfort
survey. The room temperature was controlled while the BI was monitored on the wrist (back), contrasting with the usual methodology for determining thermal comfort. Skin BI on the wrist (back) directly correlates
with thermal comfort. The bioelectrical impedance of the skin can be used as an additional variable to identify the inhabitant’s response to space and determine thermal comfort.
Measurements of heart rate, wrist temperature, forehead temperature, relative humidity, and bio-impedance, taking ambient temperature as independent variable are contained in the file.
DOI: 10.17632/4g76tmbc4z.1
title: Sustainable Acrocomia aculeata residue-based adsorbent for removal of ivermectin from aqueous solution: characterization, analysis of process variables and modelling

description: Characterization of a biosorbent based on Acrocomia aculeata epicarp; a Central Composite Design for efficiency and amount adsorbed of ivermectin onto the biosorbent in relation to process temperature, medium pH and mass of adsorbent; isotherm and kinetics adjustment for the adsorption process.
DOI: 10.15468/dl.9kyf89
title: Occurrence Download

description: A dataset containing 11262 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is one of (South Africa, Lesotho, Eswatini)",
 "TaxonKey is one of (Spheniscus demersus (Linnaeus, 1758))",
 "BasisOfRecord is one of (Human Observation, Observation)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "Year is greater than or equal to 1950",
 "OccurrenceStatus is Present",
 "DistanceFromCentroidInMeters is greater than or equal to 2000"
 ]
}

 The dataset includes 11262 records from 14 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0004323-250117142028555/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.17632/sfc5szjzmv.1
title: LDHU3_09.1050

description: ras family protein-like protein; Leishmania donovani (HU3 strain)
DOI: 10.17632/c6t8grgfym.1
title: LDHU3_09.1030

description: mt-LAF2 | Mitoribosomal LSU assembly factor 2; Leishmania donovani (HU3 strain)
DOI: 10.17632/c8z2r8p3mm.2
title: Integrative Multi-omic Analysis Reveals Conserved Cell-projection Deficits in Human Down Syndrome Brains. Rastogi et al.

description: Contains raw data and supplementary information for Rastogi et al. publication 2024
DOI: 10.17632/h4kfnz5nxw.1
title: The Effects of Affective Expectations on Affective Experience and Anhedonia among Anhedonic Patients Suffering from Major Depressive Disorder

description: this is the raw data file of the original article.
DOI: 10.17632/jdd7rf8bmn.1
title: Semantic Segmentation-Based Intermonthly Land Cover Mapping for Graz, Austria and Portorož-Izola-Koper Region, Slovenia (2017-2021)

description: This dataset provides intermonthly mapping of land cover changes from the period 2017 to 2021 for the region of Graz, Austria, and the coastal region of Portorož, Izola, and Koper in Slovenia.

In the Graz region, images were procured within the WGS84 bounding box defined by the coordinates [15.390816°, 46.942176°, 15.515785°, 47.015961°], accounting for a total of 40 images. The region of Portorož, Izola, and Koper in Slovenia, contained within the WGS84 bounding box [13.590260°, 45.506948°, 13.744411°, 45.554449°], yielded a total of 41 images. All images obtained maintain minimal cloud coverage and have a spatial resolution of 10 meters.

Comprised within this dataset are raw Sentinel-2 images in numpy format in conjunction with True Color (RGB) images in PNG format, each procured from Sentinel Hub. The ground truth label data is preserved in numpy format and has been additionally rendered in color-coded PNGs. The dataset also includes land cover maps predicted for the test set (2020-2021), as outlined in the research article, available at https://doi.org/10.3390/s23146648. Each file adheres to a nomenclature denoting the year and the month (e.g., 2017_1 corresponds to an image/ground truth/prediction for the January 2017).

Initial ground truth was obtained using the ESRI's UNet model, available at https://www.arcgis.com/home/item.html?id=afd124844ba84da69c2c533d4af10a58 (accessed on 25 July 2023). Subsequent manual corrections were administered to enhance the accuracy and integrity of the data. The Graz region contains 12 distinct classes, while the region of Portorož-Izola-Koper comprises 13 classes.

The dataset is structured as follows:
- 'classes.txt' contains a list of land cover classes,
- '/data' hosts the Sentinel-2 imagery,
-- '/data/numpy' retains Sentinel-2 images featuring 13 basic spectral layers (B01–B12) in numpy format,
-- '/data/true_color_png' stores True Color (RGB) images in PNG format,
- '/ground_truth' contains ground truth,
-- '/ground_truth/numpy' houses ground truth in numpy format with values ranging from 0 to 14 representing distinct classes,
-- '/ground_truth/color_labeled_png' contains color-labeled images in PNG format.
- '/predictions' contains predicted land cover maps for the test set from the associated research paper,
-- '/predictions/numpy' has predictions in numpy format with values ranging from 0 to 14 representing distinct classes,
-- '/predictions/color_labeled_png' contains color-labeled images in PNG format.

All these directories further include subdirectories '/graz' and '/portoroz_izola_koper' corresponding to the two regions covered in the datasets.

Acknowledgments:
Should you find this dataset useful in your work, we kindly request that you acknowledge its origin by citing the following article:
Kavran, D.; Mongus, D.; Žalik, B.; Lukač, N. Graph Neural Network-Based Method of Spatiotemporal Land Cover Mapping Using Satellite Imagery. Sensors 2023, 23, 6648. https://doi.org/10.3390/s23146648.
DOI: 10.17632/vrp9fxdg2p.1
title: LINF_320027900

description: R-SNARE protein; Leishmania infantum (strain JPCM5)
DOI: 10.6084/m9.figshare.28239287
title: 宝华山一批次6个样点形态种统计记录与同一批次宏条形码鉴定结果-3

description: 使用形态学手段将标本分为形态种，根据易于观察的形态特征来分类分类群，鉴定时在酒精湿标本上进行，使用双目显微镜，根据外部形态特征分离形态种，此外观察表面纹理，毛和颜色等进行区分，并按目级阶元统计。通过比较形态学分类与宏条形码检测的分类单元数量、科级、属级分类的差异，以及检出频次和物种数量，来验证宏条形码的可靠性。
DOI: 10.6084/m9.figshare.28239287.v1
title: 宝华山一批次6个样点形态种统计记录与同一批次宏条形码鉴定结果-3

description: 使用形态学手段将标本分为形态种，根据易于观察的形态特征来分类分类群，鉴定时在酒精湿标本上进行，使用双目显微镜，根据外部形态特征分离形态种，此外观察表面纹理，毛和颜色等进行区分，并按目级阶元统计。通过比较形态学分类与宏条形码检测的分类单元数量、科级、属级分类的差异，以及检出频次和物种数量，来验证宏条形码的可靠性。
DOI: 10.17632/frz7yh5ctr.1
title: FLOT chemotherapy treatment affects adipocyte’s lipid metabolism: an in vitro study

description: This data was used to produce the following paper, Guerrier et al., FLOT chemotherapy treatment affects adipocyte’s lipid metabolism: an in vitro study submitted in Adipocyte Journal.
DOI: 10.17632/8rn69gyjss.1
title: LINF_320027400

description: RNA binding protein | RBP39; Leishmania infantum (strain JPCM5)
DOI: 10.17632/zdp72s54cd.1
title: Multicondition training for PD diagnosis with voice features from diadochokinesis test

description: The dataset includes acoustic features extracted from voice recordings using a diadochokinesis (DDK) test protocol. Realistic environmental noise was introduced into the recordings prior to feature extraction to simulate real-world conditions. The dataset comprises voice samples from 30 Parkinson's disease (PD) patients and 30 healthy controls. All samples were captured via smartphone without audio compression to preserve data quality.
DOI: 10.17632/4r839t38sb.1
title: A combination of the frequent fungicides boscalid and dimoxystrobin with the neonicotinoid acetamiprid in field-realistic concentrations does not affect sucrose responsiveness and learning behavior of honeybees

description: The effect of the fungicide Cantus Gold and the neonicotinoid insecticide Mospilan on the mortality, the responsiveness to sucrose and the learning performance of honeybees was tested. Mortality studies were performed for a low and a high concentration to determine two suitable sublethal doses for behavioral experiments. PER (proboscis extension response) tests and olfactory conditioning were conducted to investigate possible negative synergistic effects of the plant protection products. During the PER tests, a series of sucrose concentrations was presented to the bees and the response was noted (1/0). During conditioning, a rewarded (Nonanol) and a punished odor (Eugenol) were used, which were interchanged during reversal learning. Only bees that reacted to the highest concentration of sucrose water and showed no spontaneous reaction for both odors were conditioned. It was noted when the bee showed a conditioned response. There were no treatment effects on the responsiveness to sucrose and the learning performance.
DOI: 10.17632/xcz8vb448y.1
title: COVID19 Rumor Detection

description: The data set contains information about the COVID-19 pandemic. Twitter data has been collected based on the hashtags #CoronaOutbreak, #CoronaVirus, #CoronaVirusOutbreak, #COVID19, #COVID-19, #COVID2019, and #SARSCoV2, between February 12, 2020 and June 15, 2020. 

The goal of this data set is to detect whether a tweet is identified as a rumor or not (given by the 'label' column). A tweet that is identified as a rumor is labeled as 1, and 0 otherwise. The tweets were labeled by two independent annotators using the following guidelines. Whether a tweet is a rumor or not depends on 3 important aspects: 
(1) A rumor is a piece of information that is unverified or not confirmed by official instances. In other words, it does not matter whether the information turns out to be true or false in the future. 
(2) More specifically, a tweet is a rumor if the information is unverified at the time of posting.
(3) For a tweet to be a rumor, it should contain an assertion, meaning the author of tweet commits to the truth of the message. 

In sum, the annotators indicated that a tweet is a rumor if it consisted of an assertion giving information that is unverifiable at the time of posting. Practically, to check whether the information in a tweet was verified or confirmed by official instances at the moment of tweeting, the annotators used BBC News and Reuters. After all the tweets were labeled, the annotators re-iterated over the tweets they disagreed on to produce the final tweet label.

Besides the label indicating whether a tweet is a rumor or not (i.e., ‘label’), the data set contains the tweet itself (i.e., ‘full_text’), and additional metadata (e.g., ‘created_at’, ‘favorite_count’) . In total, the data set contains 4,612 observations of which 485 (11%) are identified as rumors. 

This data set can be used by researchers to make rumor detection models (i.e., statistical, machine learning and deep learning models) using both unstructured (i.e., textual) and structured data.
DOI: 10.17632/zjfpsfd95k.1
title: From crystal phase mixture to pure metal-organic frameworks – Tuning pore and structure properties

description: The deposit contains data for the paper "From crystal phase mixture to pure metal-organic frameworks – Tuning pore and structure properties" including BET, CIF files, cRED, FTIR, Raman, QEXAFSm SXRD, XRD, SEM, TEM.
DOI: 10.17632/dkskjr8zjc.1
title: Spectrum and respondent consent form

description: Spectrum and respondent consent form
DOI: 10.17632/g6chbxf8n6.1
title: LINF_320029900

description: Nsp1-C domain-containing protein; Leishmania infantum (strain JPCM5)
DOI: 10.17632/cz68pxg9tg.1
title: LINF_320029100

description: protein of unknown function - conserved; Leishmania infantum (strain JPCM5)
DOI: 10.17632/ymw548hg6v.1
title: Audio SGA0028-2019

description: 16 Audio speech recordings SGA0028-2019