cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.19923064
title: Exome sequencing and targeted gene panels: a simulated comparison of diagnostic yield using data from 158 patients with rare diseases

description: Abstract Next-generation sequencing (NGS) has altered clinical genetic testing by widening the access to molecular diagnosis of genetically determined rare diseases. However, physicians may face difficulties selecting the best diagnostic approach. Our goal is to estimate the rate of possible molecular diagnoses missed by different targeted gene panels using data from a cohort of patients with rare genetic diseases diagnosed with exome sequencing (ES). For this purpose, we simulated a comparison between different targeted gene panels and ES: the list of genes harboring clinically relevant variants from 158 patients was used to estimate the theoretical rate of diagnoses missed by NGS panels from 53 different NGS panels from eight different laboratories. Panels presented a mean rate of missed diagnoses of 64% (range 14%-100%) compared to ES, representing an average predicted sensitivity of 36%. Metabolic abnormalities represented the group with highest mean of missed diagnoses (86%), while seizure represented the group with lowest mean (46%). Focused gene panels are restricted in covering select sets of genes implicated in specific diseases and they may miss molecular diagnoses of rare diseases compared to ES. However, their role in genetic diagnosis remains important especially for well-known genetic diseases with established genetic locus heterogeneity.
DOI: 10.6084/m9.figshare.19923064.v1
title: Exome sequencing and targeted gene panels: a simulated comparison of diagnostic yield using data from 158 patients with rare diseases

description: Abstract Next-generation sequencing (NGS) has altered clinical genetic testing by widening the access to molecular diagnosis of genetically determined rare diseases. However, physicians may face difficulties selecting the best diagnostic approach. Our goal is to estimate the rate of possible molecular diagnoses missed by different targeted gene panels using data from a cohort of patients with rare genetic diseases diagnosed with exome sequencing (ES). For this purpose, we simulated a comparison between different targeted gene panels and ES: the list of genes harboring clinically relevant variants from 158 patients was used to estimate the theoretical rate of diagnoses missed by NGS panels from 53 different NGS panels from eight different laboratories. Panels presented a mean rate of missed diagnoses of 64% (range 14%-100%) compared to ES, representing an average predicted sensitivity of 36%. Metabolic abnormalities represented the group with highest mean of missed diagnoses (86%), while seizure represented the group with lowest mean (46%). Focused gene panels are restricted in covering select sets of genes implicated in specific diseases and they may miss molecular diagnoses of rare diseases compared to ES. However, their role in genetic diagnosis remains important especially for well-known genetic diseases with established genetic locus heterogeneity.
DOI: 10.6084/m9.figshare.19923073
title: The presence of anemia in patients with leg ulcer: laboratory test

description: ABSTRACT Objective: To evaluate the presence of anemia in patients with chronic lower limb ulcers based on profile and hematometric indices. Method: This is a cross-sectional study carried out in a university hospital in Rio de Janeiro. The sample was composed of 64 participants with lower limb ulcers and evolution time greater than 12 weeks. Data was collected between May/2016 and December/2017 from hematological analyses, records from medical records, and wound assessment form. Results: 36 (56.2%) were male; 38 (59.4%) between 60 and 80 years old; 56 (87.5%) with chronic diseases and 52 (81.2%) with venous ulcers. 6 years mean of active ulceration. Anemia was detected in 36 (56.2%), 27 (75%) of which were normochromic and normocytic; 14 (38.8%) had deficiency anemia recorded in their medical chart. Conclusion: The low hemoglobin concentration is recurrent among the participants characterizing an anemia condition, whose profile reveals congruence to the anemia of chronic disease.
DOI: 10.6084/m9.figshare.19923073.v1
title: The presence of anemia in patients with leg ulcer: laboratory test

description: ABSTRACT Objective: To evaluate the presence of anemia in patients with chronic lower limb ulcers based on profile and hematometric indices. Method: This is a cross-sectional study carried out in a university hospital in Rio de Janeiro. The sample was composed of 64 participants with lower limb ulcers and evolution time greater than 12 weeks. Data was collected between May/2016 and December/2017 from hematological analyses, records from medical records, and wound assessment form. Results: 36 (56.2%) were male; 38 (59.4%) between 60 and 80 years old; 56 (87.5%) with chronic diseases and 52 (81.2%) with venous ulcers. 6 years mean of active ulceration. Anemia was detected in 36 (56.2%), 27 (75%) of which were normochromic and normocytic; 14 (38.8%) had deficiency anemia recorded in their medical chart. Conclusion: The low hemoglobin concentration is recurrent among the participants characterizing an anemia condition, whose profile reveals congruence to the anemia of chronic disease.
DOI: 10.6084/m9.figshare.19923074
title: Hemodialysis in the context of COVID-19: care, nursing protagonism and quality

description: ABSTRACT Objective: To reflect on the need to reorganize satellite dialysis units to ensure the safety of patients and workers, focusing on minimizing the risk of contamination by SARS-CoV-2. Methods: Reflection considering the guidelines of international and Brazilian institutions and scientific articles, with a view to possible adaptations to the Brazilian reality. Results: The actions suggested and adapted by Dialysis Units from different countries during the pandemic focus on the quality of care and safety of the patient and workers. There was an opportunity to reflect on these actions using the Donabedian Model for quality of care and highlight the nursing team’s role in this context. Final considerations: The focus on quality and safety related to institutionalized processes and the assessment through indicators can contribute to the management of the outpatient dialysis unit in the context of COVID 19.
DOI: 10.6084/m9.figshare.19923074.v1
title: Hemodialysis in the context of COVID-19: care, nursing protagonism and quality

description: ABSTRACT Objective: To reflect on the need to reorganize satellite dialysis units to ensure the safety of patients and workers, focusing on minimizing the risk of contamination by SARS-CoV-2. Methods: Reflection considering the guidelines of international and Brazilian institutions and scientific articles, with a view to possible adaptations to the Brazilian reality. Results: The actions suggested and adapted by Dialysis Units from different countries during the pandemic focus on the quality of care and safety of the patient and workers. There was an opportunity to reflect on these actions using the Donabedian Model for quality of care and highlight the nursing team’s role in this context. Final considerations: The focus on quality and safety related to institutionalized processes and the assessment through indicators can contribute to the management of the outpatient dialysis unit in the context of COVID 19.
DOI: 10.6084/m9.figshare.19923076
title: Implementation of evidence-based practices in the perineal pain management in the postpartum period

description: ABSTRACT Objectives: To implement strategies for managing perineal pain in puerperal women admitted to a public maternity hospital in São Paulo state and to evaluate their compliance with evidence-based practices. Methods: Implementation study using the JBI model conducted with nursing professionals and puerperal women between September and December 2019. Interviews with puerperal women and medical record data were used to audit seven evidence-based criteria. The interventions adopted included a care protocol, professional training, and folder elaboration for puerperal women. Results: Prior to the intervention, deficits in audited practices and obstacles to pain management were identified, which were overcome by the strategies employed. The follow-up audit demonstrated improvements in compliance with best care practices. Conclusion: There was an increase in the criteria compliance evaluated after the implemented strategies, contributing to improving the nursing care results in the perineal pain management based on the best scientific evidence.
DOI: 10.6084/m9.figshare.19923076.v1
title: Implementation of evidence-based practices in the perineal pain management in the postpartum period

description: ABSTRACT Objectives: To implement strategies for managing perineal pain in puerperal women admitted to a public maternity hospital in São Paulo state and to evaluate their compliance with evidence-based practices. Methods: Implementation study using the JBI model conducted with nursing professionals and puerperal women between September and December 2019. Interviews with puerperal women and medical record data were used to audit seven evidence-based criteria. The interventions adopted included a care protocol, professional training, and folder elaboration for puerperal women. Results: Prior to the intervention, deficits in audited practices and obstacles to pain management were identified, which were overcome by the strategies employed. The follow-up audit demonstrated improvements in compliance with best care practices. Conclusion: There was an increase in the criteria compliance evaluated after the implemented strategies, contributing to improving the nursing care results in the perineal pain management based on the best scientific evidence.
DOI: 10.6084/m9.figshare.19922075.v1
title: Dalechampia L. (Euphorbiaceae) in the Brazilian Amazon

description: Abstract: A taxonomic treatment of Dalechampia species found in the Brazilian Amazon is presented. The study was based on an analysis of herbarium material (including historical and type collections), specimens collected in the field, and literature. Twenty-three species, distributed in five sections, are recognized. Dalechampia hastata is endemic to the Brazilian Amazon. Among the species surveyed, thirteen species are considered to be Least Concern (LC), and not currently at risk of extinction. Six species (D. attenuistylus, D. brownsbergensis, D. fragrans, D. hastata, D. megacarpa and D. olympiana) are Endangered (EN), three species (D. gentryi, D. heterobractea and D. tenuiramea) are Near Threatened (NT), and D. liesneri is listed with Deficient Data (DD). If we consider the occurrence only in Brazil of three species , the taxa can be designated as Vulnerable (VU). Dalechampia micrantha and D. parvibracteata are lectotypified. The lectotype of D. cissifolia, D. juruana, and D. pernambucensis is clarified. New occurrences are reported for some countries. An identification key, descriptions, taxonomic comments, illustrations, the conservation status, phenological data, and geographic distribution maps are provided.
DOI: 10.6084/m9.figshare.19922075
title: Dalechampia L. (Euphorbiaceae) in the Brazilian Amazon

description: Abstract: A taxonomic treatment of Dalechampia species found in the Brazilian Amazon is presented. The study was based on an analysis of herbarium material (including historical and type collections), specimens collected in the field, and literature. Twenty-three species, distributed in five sections, are recognized. Dalechampia hastata is endemic to the Brazilian Amazon. Among the species surveyed, thirteen species are considered to be Least Concern (LC), and not currently at risk of extinction. Six species (D. attenuistylus, D. brownsbergensis, D. fragrans, D. hastata, D. megacarpa and D. olympiana) are Endangered (EN), three species (D. gentryi, D. heterobractea and D. tenuiramea) are Near Threatened (NT), and D. liesneri is listed with Deficient Data (DD). If we consider the occurrence only in Brazil of three species , the taxa can be designated as Vulnerable (VU). Dalechampia micrantha and D. parvibracteata are lectotypified. The lectotype of D. cissifolia, D. juruana, and D. pernambucensis is clarified. New occurrences are reported for some countries. An identification key, descriptions, taxonomic comments, illustrations, the conservation status, phenological data, and geographic distribution maps are provided.
DOI: 10.11588/data/eixopn/33qfjp
title: Differentially expressed genes_Discovery.tab

description: :unav
DOI: 10.11588/data/eixopn/pyi5nc
title: Pathway enrichment_Discovery.zip

description: :unav
DOI: 10.11588/data/eixopn/n2x1e4
title: QuantiGene Plex_Validation subset B.tab

description: :unav
DOI: 10.11588/data/eixopn/nzkp5t
title: QuantiGene Plex_Validation subset A.tab

description: :unav
DOI: 10.6084/m9.figshare.19923079
title: Family literacy in preschoolers’ linguistic and metalinguistic skill development

description: ABSTRACT Purpose: to verify family literacy practices with preschoolers from a public school in a municipality of the Northeast Region of Brazil. Methods: 21 parents/guardians of pre-kindergarten and kindergarten students from a public school participated in this study. A questionnaire with 18 items on the parents’/guardians’ participation in family literacy practices was develop for this research. The resulting data underwent descriptive and inferential analysis, with the significance level set at 5%. Results: the preschoolers’ mean age was 69 months, and that of the parents/guardians who answered the questionnaire was 31 years. The educational level of most parents/guardians was either high school or unfinished middle school. A significant, positive relationship, between the parents’/guardians’ educational level and the following questionnaire items was seen: paying attention to the children when they spoke, calling their attention to the sound of letters and words, and teaching/encouraging them to write their names. Conclusion: family literacy practices are not commonly developed in the culture of the Northeast Region of Brazil, and when so, most of them are similar to activities taught at school. There was also a weak correlation between the parents’/guardians’ educational level and the family literacy practices.
DOI: 10.6084/m9.figshare.19923079.v1
title: Family literacy in preschoolers’ linguistic and metalinguistic skill development

description: ABSTRACT Purpose: to verify family literacy practices with preschoolers from a public school in a municipality of the Northeast Region of Brazil. Methods: 21 parents/guardians of pre-kindergarten and kindergarten students from a public school participated in this study. A questionnaire with 18 items on the parents’/guardians’ participation in family literacy practices was develop for this research. The resulting data underwent descriptive and inferential analysis, with the significance level set at 5%. Results: the preschoolers’ mean age was 69 months, and that of the parents/guardians who answered the questionnaire was 31 years. The educational level of most parents/guardians was either high school or unfinished middle school. A significant, positive relationship, between the parents’/guardians’ educational level and the following questionnaire items was seen: paying attention to the children when they spoke, calling their attention to the sound of letters and words, and teaching/encouraging them to write their names. Conclusion: family literacy practices are not commonly developed in the culture of the Northeast Region of Brazil, and when so, most of them are similar to activities taught at school. There was also a weak correlation between the parents’/guardians’ educational level and the family literacy practices.
DOI: 10.11588/data/eixopn/ol3g9w
title: Clinical phenotype_CD15_RNA preparation characteristics cell_counts.tab

description: :unav
DOI: 10.6084/m9.figshare.19923082
title: Palliative care in Primary Health Care: an integrative literature review

description: ABSTRACT Objectives: to analyze scientific evidence on the implementation and performance of palliative care in Primary Health Care. Methods: an integrative literature review, according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses, carried out in the PubMed, SciVerse Scopus and LILACS databases, in December 2020, without a time frame. Results: 22 original scientific articles were analyzed, 14 classified as evidence level VI. The objective was to understand the experiences and roles of professionals, patients and families on palliative care in Primary Health Care, articles focused on the theme of management and organization of health services and on the importance of educational interventions on the subject. Final Considerations: evidence found relating palliative care in Primary Health Care points to the possibility of this care; health teams work closely with the family and their home, but the need to expand this theme is still perceived.
DOI: 10.6084/m9.figshare.19923082.v1
title: Palliative care in Primary Health Care: an integrative literature review

description: ABSTRACT Objectives: to analyze scientific evidence on the implementation and performance of palliative care in Primary Health Care. Methods: an integrative literature review, according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses, carried out in the PubMed, SciVerse Scopus and LILACS databases, in December 2020, without a time frame. Results: 22 original scientific articles were analyzed, 14 classified as evidence level VI. The objective was to understand the experiences and roles of professionals, patients and families on palliative care in Primary Health Care, articles focused on the theme of management and organization of health services and on the importance of educational interventions on the subject. Final Considerations: evidence found relating palliative care in Primary Health Care points to the possibility of this care; health teams work closely with the family and their home, but the need to expand this theme is still perceived.
DOI: 10.6084/m9.figshare.19923083.v1
title: Support group for families with children in a pediatric intensive care unit

description: ABSTRACT Objective: To describe the process of creating and implementing a support group for families with children in a pediatric intensive care unit. Methods: A professional experience report described using a management and planning tool. Results: This is a pioneering initiative in the hospital. The application of the tool enabled the delineation of the scope, justification, location, frequency, responsible persons, approach, and budget. After its implementation, the group enables significant interaction between health professionals-families and families-families, favoring the formation of therapeutic bonds and stimulating social and emotional support networks. Conclusion: The tool effectively planned the group and highlighted its effects on family coping and the relationships between professionals and families.
DOI: 10.6084/m9.figshare.19923083
title: Support group for families with children in a pediatric intensive care unit

description: ABSTRACT Objective: To describe the process of creating and implementing a support group for families with children in a pediatric intensive care unit. Methods: A professional experience report described using a management and planning tool. Results: This is a pioneering initiative in the hospital. The application of the tool enabled the delineation of the scope, justification, location, frequency, responsible persons, approach, and budget. After its implementation, the group enables significant interaction between health professionals-families and families-families, favoring the formation of therapeutic bonds and stimulating social and emotional support networks. Conclusion: The tool effectively planned the group and highlighted its effects on family coping and the relationships between professionals and families.
DOI: 10.15468/dl.bfmbzt
title: Occurrence Download

description: A dataset containing 46 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Colombia",
 "GadmGid is COL.25_1",
 "TaxonKey is Deltochilum hypponum (Buquet, 1844)",
 "Year 1000-2010"
 ]
}

 The dataset includes 46 records from 3 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0325308-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.usrk8p
title: Occurrence Download

description: A dataset containing 16928 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON ((5.925 50.825,5.975 50.825,5.975 50.875,5.925 50.875,5.925 50.825))",
 "DatasetKey is Observation.org, Nature data from around the World",
 "TaxonKey is Animalia"
 ]
}

 The dataset includes 16928 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0306982-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.a5udqw
title: Occurrence Download

description: A dataset containing 13 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Specimen",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "TaxonKey is Elymandra archaelymandra (Jacq.-Fél.) Clayton"
 ]
}

 The dataset includes 13 records from 5 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0294705-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.pt7c2x
title: Occurrence Download

description: A dataset containing 705 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Plectranthus ciliatus E.Mey.)",
 "HasCoordinate is true"
 ]
}

 The dataset includes 705 records from 23 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0051705-240506114902167/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.8s3hnu
title: Occurrence Download

description: A dataset containing 1075 species occurrences available in GBIF matching the query:
{
 "and" : [
 {
 "or" : [
 "BasisOfRecord is Human Observation",
 "BasisOfRecord is Material sample",
 "BasisOfRecord is Specimen"
 ]
 },
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "TaxonKey is Anthodioctes Holmberg, 1903",
 "Year 1960-2021"
 ]
}

 The dataset includes 1075 records from 16 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0314027-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.ypqmpj
title: Occurrence Download

description: A dataset containing 763 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Allium fistulosum L.",
 "HasCoordinate is true"
 ]
}

 The dataset includes 763 records from 130 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0035193-231120084113126/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.dxtahd
title: Occurrence Download

description: A dataset containing 232 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Specimen",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Hyloscirtus palmeri (Boulenger, 1908)"
 ]
}

 The dataset includes 232 records from 15 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0265903-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.