cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.1470034.v1
title: Questionnaire on RadioMarche Usage Nov/Oct 2012

description: RadioMarche feedback report.
DOI: 10.6084/m9.figshare.1470130.v1
title: Estrogen receptor alpha (ESR1) gene amplification is frequent in breast cancer. Subsequent Supplementary Optical Dataset S1

description: <strong>Estrogen receptor alpha (ESR1) gene amplification is frequent in breast cancer. Subsequent Supplementary Material.</strong> Frederik Holst & Christian Ruiz The supplementary material refers to: Holst, F., Stahl, P.R., Ruiz, C., et al. Estrogen receptor alpha (ESR1) gene amplification s frequent in breast cancer. Nature Genetics 39, 655-660 (2007). <strong>Subsequent Supplementary Figures S1-S7</strong> Illustration of the different Affymetrix 10K SNP array gene copy number data analysis methods and regarding segmented ESR1 copy number profiles of 22 breast cancers. Taken from Subsequent Supplementary Optical Dataset S1 a photographical documentation of <em>ESR1</em> FISH analysis signal appearance of tumors with <em>ESR1</em> amplification by SNP GeneChip analysis is added (figures 5A-C + 7A-C). DOI: http://dx.doi.org/10.6084/m9.figshare.1470035 <strong>Subsequent Supplementary Video Clips S1+S2</strong> The video clips document FISH analysis as performed for results documented in regarding subsequent supplementary figures 5A-C + 7A-C. Video clips are taken using an Olympus IX51 microscope at 100x magnification, an Olympus XM10 digital camera (1,376 x 1,032 pixels) and Olympus cellSens imaging software. DOI: http://dx.doi.org/10.6084/m9.figshare.1471677 <strong>Subsequent Supplementary Optical Dataset S1</strong> The optical dataset consists of 94 photographs documenting appearance of <em>ESR1</em> FISH analysis signals of 20 out of 22 tumors regarding SNP GeneChip analysis illustrated in subsequent supplementary figures S1-S3 and S4+S6. The 94 photographs are separated into 1-10 figures per tumor including up to three z-stacks per figure. Photographs are taken using an Olympus IX51 microscope at 100x magnification, an Olympus XM10 digital camera (1,376 ´ 1,032 pixels) and Olympus cellSens imaging software. DOI: http://dx.doi.org/10.6084/m9.figshare.1470130 <strong>Methods References</strong> Ruiz, C. Doctoral Thesis, Universität Basel (2006). Moelans, C.B., Holst, F., Hellwinkel, O., Simon, R. & van Diest, P.J. ESR1 Amplification in Breast Cancer by Optimized RNase FISH: Frequent but Low-Level and Heterogeneous. PLoS One 8, e84189 (2013). Holst, F. FISH Analysis of ESR1 Amplification in Breast Cancer - A Video Illustration. DOI: http://dx.doi.org/10.6084/m9.figshare.1471765 (2015).
DOI: 10.6084/m9.figshare.1470035.v3
title: Estrogen receptor alpha (ESR1) gene amplification is frequent in breast cancer. Subsequent Supplementary Figures S1-S7

description: <strong>Estrogen receptor alpha (<em>ESR1</em>) gene amplification is frequent in breast cancer. Subsequent Supplementary Material.</strong> Frederik Holst & Christian Ruiz The supplementary material refers to: Holst, F., Stahl, P.R., Ruiz, C., et al. Estrogen receptor alpha (<em>ESR1</em>) gene amplification s frequent in breast cancer. Nature Genetics 39, 655-660 (2007). <strong>Subsequent Supplementary Figures S1-S7</strong> Illustration of the different Affymetrix 10K SNP array gene copy number data analysis methods and regarding segmented <em>ESR1</em> copy number profiles of 22 breast cancers. Taken from Subsequent Supplementary Optical Dataset S1 a photographical documentation of <em>ESR1</em> FISH analysis signal appearance of tumors with <em>ESR1</em> amplification by SNP GeneChip analysis is added (figures 5A-C + 7A-C). DOI: http://dx.doi.org/10.6084/m9.figshare.1470035 <strong>Subsequent Supplementary Video Clips S1+S2</strong> The video clips document FISH analysis as performed for results documented in regarding subsequent supplementary figures 5A-C + 7A-C. Video clips are taken using an Olympus IX51 microscope at 100x magnification, an Olympus XM10 digital camera (1,376 x 1,032 pixels) and Olympus cellSens imaging software. DOI: http://dx.doi.org/10.6084/m9.figshare.1471677 <strong>Subsequent Supplementary Optical Dataset S1</strong> The optical dataset consists of 94 photographs documenting appearance of <em>ESR1</em> FISH analysis signals of 20 out of 22 tumors regarding SNP GeneChip analysis illustrated in subsequent supplementary figures S1-S3 and S4+S6. The 94 photographs are separated into 1-10 figures per tumor including up to three z-stacks per figure. Photographs are taken using an Olympus IX51 microscope at 100x magnification, an Olympus XM10 digital camera (1,376 ´ 1,032 pixels) and Olympus cellSens imaging software. DOI: http://dx.doi.org/10.6084/m9.figshare.1470130 <strong>Methods References</strong> Ruiz, C. Doctoral Thesis, Universität Basel (2006). Moelans, C.B., Holst, F., Hellwinkel, O., Simon, R. & van Diest, P.J. <em>ESR1</em> Amplification in Breast Cancer by Optimized RNase FISH: Frequent but Low-Level and Heterogeneous. PLoS One 8, e84189 (2013). Holst, F. FISH Analysis of <em>ESR1</em> Amplification in Breast Cancer - A Video Illustration. DOI: http://dx.doi.org/10.6084/m9.figshare.1471765 (2015).
DOI: 10.6084/m9.figshare.1470130.v2
title: Estrogen receptor alpha (ESR1) gene amplification is frequent in breast cancer. Subsequent Supplementary Optical Dataset S1

description: <strong>Estrogen receptor alpha (<em>ESR1</em>) gene amplification is frequent in breast cancer. Subsequent Supplementary Material.</strong> Frederik Holst & Christian Ruiz The supplementary material refers to: Holst, F., Stahl, P.R., Ruiz, C., et al. Estrogen receptor alpha (<em>ESR1</em>) gene amplification s frequent in breast cancer. Nature Genetics 39, 655-660 (2007). <strong>Subsequent Supplementary Figures S1-S7</strong> Illustration of the different Affymetrix 10K SNP array gene copy number data analysis methods and regarding segmented <em>ESR1</em> copy number profiles of 22 breast cancers. Taken from Subsequent Supplementary Optical Dataset S1 a photographical documentation of <em>ESR1</em> FISH analysis signal appearance of tumors with <em>ESR1</em> amplification by SNP GeneChip analysis is added (figures 5A-C + 7A-C). DOI: http://dx.doi.org/10.6084/m9.figshare.1470035 <strong>Subsequent Supplementary Video Clips S1+S2</strong> The video clips document FISH analysis as performed for results documented in regarding subsequent supplementary figures 5A-C + 7A-C. Video clips are taken using an Olympus IX51 microscope at 100x magnification, an Olympus XM10 digital camera (1,376 x 1,032 pixels) and Olympus cellSens imaging software. DOI: http://dx.doi.org/10.6084/m9.figshare.1471677 <strong>Subsequent Supplementary Optical Dataset S1</strong> The optical dataset consists of 94 photographs documenting appearance of <em>ESR1</em> FISH analysis signals of 20 out of 22 tumors regarding SNP GeneChip analysis illustrated in subsequent supplementary figures S1-S3 and S4+S6. The 94 photographs are separated into 1-10 figures per tumor including up to three z-stacks per figure. Photographs are taken using an Olympus IX51 microscope at 100x magnification, an Olympus XM10 digital camera (1,376 ´ 1,032 pixels) and Olympus cellSens imaging software. DOI: http://dx.doi.org/10.6084/m9.figshare.1470130 <strong>Methods References</strong> Ruiz, C. Doctoral Thesis, Universität Basel (2006). Moelans, C.B., Holst, F., Hellwinkel, O., Simon, R. & van Diest, P.J. <em>ESR1</em> Amplification in Breast Cancer by Optimized RNase FISH: Frequent but Low-Level and Heterogeneous. PLoS One 8, e84189 (2013). Holst, F. FISH Analysis of <em>ESR1</em> Amplification in Breast Cancer - A Video Illustration. DOI: http://dx.doi.org/10.6084/m9.figshare.1471765 (2015).
DOI: 10.6084/m9.figshare.1468813
title: Alteplase - analysis of clinical trial registries

description: <strong>Alteplase ClinicalTrials.gov (completed before Jan 1, 2013) = 126 registries (NCT numbers)</strong> PubMed: Not found = 83 Found (registries matching an article indexed by PubMed) = 43 (73 PubMed articles) Alteplase database of clinical trial registries: open (comments allowed by default): 1. Google Drive Spreadsheets. https://docs.google.com/spreadsheets/d/1QiqSjI0wOnhk40AXvZCtQJFLQPk6S2ZSN7sgZ5ERzYI/edit#gid=373090936 2. figshare Version 1.0: ClinicalTrials.gov - PubMed (initial search query).
DOI: 10.6084/m9.figshare.1469659.v1
title: Studies of wild bird populations have shown that exploratory behaviour is associated with polymorphisms in DRD4. Additionally high levels of anxiety, a characteristic of bold behaviour, and exploratory behaviour have been associated with polymorphisms in

description: Studies of wild bird populations have shown that exploratory behaviour is associated with polymorphisms in DRD4. Additionally high levels of anxiety, a characteristic of bold behaviour, and exploratory behaviour have been associated with polymorphisms in SERT. Here we tested for polymorphisms in DRD4 and SERT in the Seychelles warbler (Acrocephalus sechellensis) population on Cousin Island, Seychelles, and then investigated correlations between personality and polymorphisms in these genes.
DOI: 10.6084/m9.figshare.1470035.v4
title: Estrogen receptor alpha (ESR1) gene amplification is frequent in breast cancer. Subsequent Supplementary Figures S1-S7

description: <strong>Estrogen receptor alpha (<em>ESR1</em>) gene amplification is frequent in breast cancer. Subsequent Supplementary Material.</strong> Frederik Holst & Christian Ruiz The supplementary material refers to: Holst, F., Stahl, P.R., Ruiz, C., et al. Estrogen receptor alpha (<em>ESR1</em>) gene amplification s frequent in breast cancer. Nature Genetics 39, 655-660 (2007). <strong>Subsequent Supplementary Figures S1-S7</strong> Illustration of the different Affymetrix 10K SNP array gene copy number data analysis methods and regarding segmented <em>ESR1</em> copy number profiles of 22 breast cancers. Taken from Subsequent Supplementary Optical Dataset S1 a photographical documentation of <em>ESR1</em> FISH analysis signal appearance of tumors with <em>ESR1</em> amplification by SNP GeneChip analysis is added (figures 5A-C + 7A-C). DOI: http://dx.doi.org/10.6084/m9.figshare.1470035 <strong>Subsequent Supplementary Video Clips S1+S2</strong> The video clips document FISH analysis as performed for results documented in regarding subsequent supplementary figures 5A-C + 7A-C. Video clips are taken using an Olympus IX51 microscope at 100x magnification, an Olympus XM10 digital camera (1,376 x 1,032 pixels) and Olympus cellSens imaging software. DOI: http://dx.doi.org/10.6084/m9.figshare.1471677 <strong>Subsequent Supplementary Optical Dataset S1</strong> The optical dataset consists of 94 photographs documenting appearance of <em>ESR1</em> FISH analysis signals of 20 out of 22 tumors regarding SNP GeneChip analysis illustrated in subsequent supplementary figures S1-S3 and S4+S6. The 94 photographs are separated into 1-10 figures per tumor including up to three z-stacks per figure. Photographs are taken using an Olympus IX51 microscope at 100x magnification, an Olympus XM10 digital camera (1,376 ´ 1,032 pixels) and Olympus cellSens imaging software. DOI: http://dx.doi.org/10.6084/m9.figshare.1470130 <strong>Methods References</strong> Ruiz, C. Doctoral Thesis, Universität Basel (2006). Moelans, C.B., Holst, F., Hellwinkel, O., Simon, R. & van Diest, P.J. <em>ESR1</em> Amplification in Breast Cancer by Optimized RNase FISH: Frequent but Low-Level and Heterogeneous. PLoS One 8, e84189 (2013). Holst, F. FISH Analysis of <em>ESR1</em> Amplification in Breast Cancer - A Video Illustration. DOI: http://dx.doi.org/10.6084/m9.figshare.1471765 (2015).
DOI: 10.6084/m9.figshare.1470130.v4
title: Estrogen receptor alpha (ESR1) gene amplification is frequent in breast cancer. Subsequent supplementary optical dataset S1

description: <strong>Estrogen receptor alpha (<em>ESR1</em>) gene amplification is frequent in breast cancer. Subsequent supplementary material.</strong> Frederik Holst & Christian Ruiz The supplementary material refers to: Holst, F., Stahl, P.R., Ruiz, C., et al. Estrogen receptor alpha (<em>ESR1</em>) gene amplification s frequent in breast cancer. Nature Genetics 39, 655-660 (2007). <strong>Subsequent Supplementary Figures S1-S7</strong> Illustration of the different Affymetrix 10K SNP array gene copy number data analysis methods and regarding segmented <em>ESR1</em> copy number profiles of 22 breast cancers. Taken from Subsequent Supplementary Optical Dataset S1 a photographical documentation of <em>ESR1</em> FISH analysis signal appearance of tumors with <em>ESR1</em> amplification by SNP GeneChip analysis is added (figures 5A-C + 7A-C). DOI: http://dx.doi.org/10.6084/m9.figshare.1470035 <strong>Subsequent Supplementary Video Clips S1+S2</strong> The video clips document FISH analysis as performed for results documented in regarding subsequent supplementary figures 5A-C + 7A-C. Video clips are taken using an Olympus IX51 microscope at 100x magnification, an Olympus XM10 digital camera (1,376 x 1,032 pixels) and Olympus cellSens imaging software. DOI: http://dx.doi.org/10.6084/m9.figshare.1471677 <strong>Subsequent Supplementary Optical Dataset S1</strong> The optical dataset consists of 94 photographs that show the appearance of <i>ESR1</i> FISH signals of 20 out of 22 tumors in regard to the GeneChip analysis that is illustrated in subsequent supplementary figures S1-S3 and S4+S6. The 94 photographs are separated into 1-10 figures per tumor including up to three z-stacks per figure. Photographs are taken using an Olympus IX51 microscope at 100x magnification, an Olympus XM10 digital camera (1,376 ´ 1,032 pixels) and Olympus cellSens imaging software. DOI: http://dx.doi.org/10.6084/m9.figshare.1470130 <strong>Methods References</strong> Ruiz, C. Doctoral Thesis, Universität Basel (2006). Moelans, C.B., Holst, F., Hellwinkel, O., Simon, R. & van Diest, P.J. <em>ESR1</em> Amplification in Breast Cancer by Optimized RNase FISH: Frequent but Low-Level and Heterogeneous. PLoS One 8, e84189 (2013). Holst, F. FISH Analysis of <em>ESR1</em> Amplification in Breast Cancer - A Video Illustration. DOI: http://dx.doi.org/10.6084/m9.figshare.1471765 (2015).
DOI: 10.6084/m9.figshare.1470035.v6
title: Estrogen receptor alpha (ESR1) gene amplification is frequent in breast cancer. Subsequent Supplementary Figures S1-S7

description: <strong>Estrogen receptor alpha (<em>ESR1</em>) gene amplification is frequent in breast cancer. Subsequent supplementary material.</strong> Frederik Holst & Christian Ruiz The supplementary material refers to: Holst, F., Stahl, P.R., Ruiz, C., et al. Estrogen receptor alpha (<em>ESR1</em>) gene amplification s frequent in breast cancer. Nature Genetics 39, 655-660 (2007). <strong>Subsequent Supplementary Figures S1-S7</strong> Illustration of the different Affymetrix 10K SNP array gene copy number data analysis methods and regarding segmented <em>ESR1</em> copy number profiles of 22 breast cancers. Taken from Subsequent Supplementary Optical Dataset S1 a photographical documentation of <em>ESR1</em> FISH analysis signal appearance of tumors with <em>ESR1</em> amplification by SNP GeneChip analysis is added (figures 5A-C + 7A-C). DOI: http://dx.doi.org/10.6084/m9.figshare.1470035 <strong>Subsequent Supplementary Video Clips S1+S2</strong> The video clips document FISH analysis as performed for results documented in regarding subsequent supplementary figures 5A-C + 7A-C. Video clips are taken using an Olympus IX51 microscope at 100x magnification, an Olympus XM10 digital camera (1,376 x 1,032 pixels) and Olympus cellSens imaging software. DOI: http://dx.doi.org/10.6084/m9.figshare.1471677 <strong>Subsequent Supplementary Optical Dataset S1</strong> The optical dataset consists of 94 photographs that show the appearance of <i>ESR1</i> FISH signals of 20 out of 22 tumors in regard to the GeneChip analysis that is illustrated in subsequent supplementary figures S1-S3 and S4+S6. The 94 photographs are separated into 1-10 figures per tumor including up to three z-stacks per figure. Photographs are taken using an Olympus IX51 microscope at 100x magnification, an Olympus XM10 digital camera (1,376 ´ 1,032 pixels) and Olympus cellSens imaging software. DOI: http://dx.doi.org/10.6084/m9.figshare.1470130 <strong>Methods References</strong> Ruiz, C. Doctoral Thesis, Universität Basel (2006). Moelans, C.B., Holst, F., Hellwinkel, O., Simon, R. & van Diest, P.J. <em>ESR1</em> Amplification in Breast Cancer by Optimized RNase FISH: Frequent but Low-Level and Heterogeneous. PLoS One 8, e84189 (2013). Holst, F. FISH Analysis of <em>ESR1</em> Amplification in Breast Cancer - A Video Illustration. DOI: http://dx.doi.org/10.6084/m9.figshare.1471765 (2015).
DOI: 10.6084/m9.figshare.1468812
title: Sample DEC from DTI

description: Example color coded direction map from DTI
DOI: 10.6084/m9.figshare.1470035.v5
title: Estrogen receptor alpha (ESR1) gene amplification is frequent in breast cancer. Subsequent supplementary figures S1-S7

description: <strong>Estrogen receptor alpha (<em>ESR1</em>) gene amplification is frequent in breast cancer. Subsequent supplementary material.</strong> Frederik Holst & Christian Ruiz The supplementary material refers to: Holst, F., Stahl, P.R., Ruiz, C., et al. Estrogen receptor alpha (<em>ESR1</em>) gene amplification s frequent in breast cancer. Nature Genetics 39, 655-660 (2007). <strong>Subsequent Supplementary Figures S1-S7</strong> Illustration of the different Affymetrix 10K SNP array gene copy number data analysis methods and regarding segmented <em>ESR1</em> copy number profiles of 22 breast cancers. Taken from Subsequent Supplementary Optical Dataset S1 a photographical documentation of <em>ESR1</em> FISH analysis signal appearance of tumors with <em>ESR1</em> amplification by SNP GeneChip analysis is added (figures 5A-C + 7A-C). DOI: http://dx.doi.org/10.6084/m9.figshare.1470035 <strong>Subsequent Supplementary Video Clips S1+S2</strong> The video clips document FISH analysis as performed for results documented in regarding subsequent supplementary figures 5A-C + 7A-C. Video clips are taken using an Olympus IX51 microscope at 100x magnification, an Olympus XM10 digital camera (1,376 x 1,032 pixels) and Olympus cellSens imaging software. DOI: http://dx.doi.org/10.6084/m9.figshare.1471677 <strong>Subsequent Supplementary Optical Dataset S1</strong> The optical dataset consists of 94 photographs that show the appearance of <i>ESR1</i> FISH signals of 20 out of 22 tumors in regard to the GeneChip analysis that is illustrated in subsequent supplementary figures S1-S3 and S4+S6. The 94 photographs are separated into 1-10 figures per tumor including up to three z-stacks per figure. Photographs are taken using an Olympus IX51 microscope at 100x magnification, an Olympus XM10 digital camera (1,376 ´ 1,032 pixels) and Olympus cellSens imaging software. DOI: http://dx.doi.org/10.6084/m9.figshare.1470130 <strong>Methods References</strong> Ruiz, C. Doctoral Thesis, Universität Basel (2006). Moelans, C.B., Holst, F., Hellwinkel, O., Simon, R. & van Diest, P.J. <em>ESR1</em> Amplification in Breast Cancer by Optimized RNase FISH: Frequent but Low-Level and Heterogeneous. PLoS One 8, e84189 (2013). Holst, F. FISH Analysis of <em>ESR1</em> Amplification in Breast Cancer - A Video Illustration. DOI: http://dx.doi.org/10.6084/m9.figshare.1471765 (2015).
DOI: 10.6084/m9.figshare.1470130.v3
title: Estrogen receptor alpha (ESR1) gene amplification is frequent in breast cancer. Subsequent Supplementary Optical Dataset S1

description: <strong>Estrogen receptor alpha (<em>ESR1</em>) gene amplification is frequent in breast cancer. Subsequent supplementary material.</strong> Frederik Holst & Christian Ruiz The supplementary material refers to: Holst, F., Stahl, P.R., Ruiz, C., et al. Estrogen receptor alpha (<em>ESR1</em>) gene amplification s frequent in breast cancer. Nature Genetics 39, 655-660 (2007). <strong>Subsequent Supplementary Figures S1-S7</strong> Illustration of the different Affymetrix 10K SNP array gene copy number data analysis methods and regarding segmented <em>ESR1</em> copy number profiles of 22 breast cancers. Taken from Subsequent Supplementary Optical Dataset S1 a photographical documentation of <em>ESR1</em> FISH analysis signal appearance of tumors with <em>ESR1</em> amplification by SNP GeneChip analysis is added (figures 5A-C + 7A-C). DOI: http://dx.doi.org/10.6084/m9.figshare.1470035 <strong>Subsequent Supplementary Video Clips S1+S2</strong> The video clips document FISH analysis as performed for results documented in regarding subsequent supplementary figures 5A-C + 7A-C. Video clips are taken using an Olympus IX51 microscope at 100x magnification, an Olympus XM10 digital camera (1,376 x 1,032 pixels) and Olympus cellSens imaging software. DOI: http://dx.doi.org/10.6084/m9.figshare.1471677 <strong>Subsequent Supplementary Optical Dataset S1</strong> The optical dataset consists of 94 photographs that show the appearance of <i>ESR1</i> FISH signals of 20 out of 22 tumors in regard to the GeneChip analysis that is illustrated in subsequent supplementary figures S1-S3 and S4+S6. The 94 photographs are separated into 1-10 figures per tumor including up to three z-stacks per figure. Photographs are taken using an Olympus IX51 microscope at 100x magnification, an Olympus XM10 digital camera (1,376 ´ 1,032 pixels) and Olympus cellSens imaging software. DOI: http://dx.doi.org/10.6084/m9.figshare.1470130 <strong>Methods References</strong> Ruiz, C. Doctoral Thesis, Universität Basel (2006). Moelans, C.B., Holst, F., Hellwinkel, O., Simon, R. & van Diest, P.J. <em>ESR1</em> Amplification in Breast Cancer by Optimized RNase FISH: Frequent but Low-Level and Heterogeneous. PLoS One 8, e84189 (2013). Holst, F. FISH Analysis of <em>ESR1</em> Amplification in Breast Cancer - A Video Illustration. DOI: http://dx.doi.org/10.6084/m9.figshare.1471765 (2015).
DOI: 10.6084/m9.figshare.1468812.v1
title: Sample DEC from DTI

description: Example color coded direction map from DTI
DOI: 10.6084/m9.figshare.1469659.v3
title: Studies of wild bird populations have shown that exploratory behaviour is associated with polymorphisms in DRD4. Additionally high levels of anxiety, a characteristic of bold behaviour, and exploratory behaviour have been associated with polymorphisms in SERT.

description: Studies of wild bird populations have shown that exploratory behaviour is associated with polymorphisms in DRD4. Additionally high levels of anxiety, a characteristic of bold behaviour, and exploratory behaviour have been associated with polymorphisms in SERT. Here we tested for polymorphisms in DRD4 and SERT in the Seychelles warbler (Acrocephalus sechellensis) population on Cousin Island, Seychelles, and then investigated correlations between personality and polymorphisms in these genes.
DOI: 10.6084/m9.figshare.1468601
title: A Change Point Approach for Phase-I Analysis in Multivariate Profile Monitoring and Diagnosis

description: Process monitoring and fault diagnosis using profile data remains an important and challenging problem in statistical process control (SPC). Although the analysis of profile data has been extensively studied in the SPC literature, the challenges associated with monitoring and diagnosis of multichannel (multiple) nonlinear profiles are yet to be addressed. Motivated by an application in multi-operation forging processes, we propose a new modeling, monitoring and diagnosis framework for phase-I analysis of multichannel profiles. The proposed framework is developed under the assumption that different profile channels have similar structure so that we can gain strength by borrowing information from all channels. The multi-dimensional functional principal component analysis is incorporated into change-point models to construct monitoring statistics. Simulation results show that the proposed approach has good performance in identifying change-points in various situations compared with some existing methods. The codes for implementing the proposed procedure are available in the supplementary material.