cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.15468/dl.tdr4yc
title: Occurrence Download

description: A dataset containing 22163 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Loxodonta africana",
 "HasCoordinate is true"
 ]
}

 The dataset includes 22163 records from 75 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0002560-260208012135463/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.bxyrga
title: Occurrence Download

description: A dataset containing 832 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen)"
 ]
 }
 },
 "TaxonKey is Aristida ingrata"
 ]
}

 The dataset includes 832 records from 21 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0002561-260208012135463/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.pduy7b
title: Occurrence Download

description: A dataset containing 59 species occurrences available in GBIF matching the query:
{
 "and" : [
 "DatasetKey is iNaturalist Research-grade Observations",
 "GadmGid is ESP.2.3_1",
 "Geometry POLYGON((-14.67769 34.32706,4.96533 34.32706,4.96533 42.18090,-14.67769 42.18090,-14.67769 34.32706))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Passer domesticus",
 "Year 2018-2023"
 ]
}

 The dataset includes 59 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0002562-260208012135463/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.34740/kaggle/dsv/14783933
title: Peer-to-Peer Boliviano (BOB) Exchange Data
DOI: 10.5281/zenodo.18546331
title: QSAR models for MIE/KE underlying cardiotoxic effects

description: They are models. They are ready to use, by downloading the VEGA softwarehttps://www.vegahub.eu/portfolio-item/vega-qsar/
DOI: 10.5281/zenodo.18546332
title: QSAR models for MIE/KE underlying cardiotoxic effects

description: They are models. They are ready to use, by downloading the VEGA softwarehttps://www.vegahub.eu/portfolio-item/vega-qsar/
DOI: 10.6084/m9.figshare.30862379
title: A systematic review of cost-effectiveness studies of later-line treatments for refractory metastatic colorectal cancer

description: This study aims to conduct a systematic review of cost-effectiveness studies evaluating later-line treatments for refractory metastatic colorectal cancer. This study conducted a literature search using PubMed, Cochrane, and Embase databases. Search terms included keywords related to colorectal cancer, regorafenib, trifluridine–tipiracil, fruquintinib, and cost-effectiveness analysis. Extracted data encompassed cost-effectiveness outcomes, methodological characteristics, and the seven parameters exerting the greatest influence on incremental cost-effectiveness ratio (ICER) results. Among 183 studies screened, a total of 11 studies met the inclusion criteria. Most studies concluded that later-line treatments for refractory metastatic colorectal cancer were not cost-effective compared to best supportive care (BSC). However, trifluridine–tipiracil was found to be cost-effective compared to BSC in some studies, and several studies reported it as a dominant option over regorafenib. Nonetheless, the cost-effectiveness outcomes between trifluridine–tipiracil and regorafenib were inconsistent across studies. Overall, drug costs and health utility values in the progressed disease state were identified as having the greatest impact on ICER outcomes. Later-line treatments were generally not found to be cost-effective compared to BSC, mainly due to high drug costs. No treatment showed consistently favorable results across studies, with outcomes varying by comparator, country, and model settings. PROSPERO (CRD420251243616)
DOI: 10.6084/m9.figshare.30862379.v1
title: A systematic review of cost-effectiveness studies of later-line treatments for refractory metastatic colorectal cancer

description: This study aims to conduct a systematic review of cost-effectiveness studies evaluating later-line treatments for refractory metastatic colorectal cancer. This study conducted a literature search using PubMed, Cochrane, and Embase databases. Search terms included keywords related to colorectal cancer, regorafenib, trifluridine–tipiracil, fruquintinib, and cost-effectiveness analysis. Extracted data encompassed cost-effectiveness outcomes, methodological characteristics, and the seven parameters exerting the greatest influence on incremental cost-effectiveness ratio (ICER) results. Among 183 studies screened, a total of 11 studies met the inclusion criteria. Most studies concluded that later-line treatments for refractory metastatic colorectal cancer were not cost-effective compared to best supportive care (BSC). However, trifluridine–tipiracil was found to be cost-effective compared to BSC in some studies, and several studies reported it as a dominant option over regorafenib. Nonetheless, the cost-effectiveness outcomes between trifluridine–tipiracil and regorafenib were inconsistent across studies. Overall, drug costs and health utility values in the progressed disease state were identified as having the greatest impact on ICER outcomes. Later-line treatments were generally not found to be cost-effective compared to BSC, mainly due to high drug costs. No treatment showed consistently favorable results across studies, with outcomes varying by comparator, country, and model settings. PROSPERO (CRD420251243616)
DOI: 10.6084/m9.figshare.30939488
title: Cost-effectiveness of mechanical thrombectomy versus intravenous thrombolysis in acute ischemic stroke: a systematic review

description: Mechanical thrombectomy (MT) is a proven treatment for acute ischemic stroke (AIS), yet its cost-effectiveness across global settings remains unclear. This systematic review synthesizes cost-effectiveness evidence and introduces a framework for evaluating MT across different health systems. Following PRISMA 2020 guidelines, comprehensive searches were conducted across four major databases to identify full economic evaluations comparing MT with intravenous thrombolysis (IVT). Methodological quality was assessed using the Quality of Health Economic Studies (QHES) checklist, and findings were synthesized qualitatively. Incremental cost-effectiveness ratios (ICERs) were converted to 2024 US dollars. Studies were categorized by income level, modeling approach, perspective, and real-world vs. trial-based data. Of 4550 records screened, 56 met the inclusion criteria. The mean QHES score was 0.83, indicating high quality. MT was consistently cost-effective or dominant across diverse healthcare contexts. Sensitivity analyses indicated that ICER variability was primarily influenced by device costs, patient age, time horizon, acute care costs, and input data used for functional outcomes and utility weights. MT is a high-value intervention, but its cost-effectiveness is context-dependent. Our classification framework supports localized decision-making. Future research should address geographic inequities in existing economic evaluations and expand evidence from low-resource settings and also integrate real-world data. PROSPERO (CRD42024496552).
DOI: 10.6084/m9.figshare.30939488.v1
title: Cost-effectiveness of mechanical thrombectomy versus intravenous thrombolysis in acute ischemic stroke: a systematic review

description: Mechanical thrombectomy (MT) is a proven treatment for acute ischemic stroke (AIS), yet its cost-effectiveness across global settings remains unclear. This systematic review synthesizes cost-effectiveness evidence and introduces a framework for evaluating MT across different health systems. Following PRISMA 2020 guidelines, comprehensive searches were conducted across four major databases to identify full economic evaluations comparing MT with intravenous thrombolysis (IVT). Methodological quality was assessed using the Quality of Health Economic Studies (QHES) checklist, and findings were synthesized qualitatively. Incremental cost-effectiveness ratios (ICERs) were converted to 2024 US dollars. Studies were categorized by income level, modeling approach, perspective, and real-world vs. trial-based data. Of 4550 records screened, 56 met the inclusion criteria. The mean QHES score was 0.83, indicating high quality. MT was consistently cost-effective or dominant across diverse healthcare contexts. Sensitivity analyses indicated that ICER variability was primarily influenced by device costs, patient age, time horizon, acute care costs, and input data used for functional outcomes and utility weights. MT is a high-value intervention, but its cost-effectiveness is context-dependent. Our classification framework supports localized decision-making. Future research should address geographic inequities in existing economic evaluations and expand evidence from low-resource settings and also integrate real-world data. PROSPERO (CRD42024496552).
DOI: 10.6084/m9.figshare.31047969
title: Cost-utility of pre-emptive plerixafor versus rescue plerixafor in the mobilization of hematopoietic stem cells in multiple myeloma

description: Multiple myeloma (MM) is a hematologic cancer with rising incidence worldwide. Autologous stem cell transplantation (ASCT) is a key treatment for eligible patients, but mobilization failure remains a major obstacle. Plerixafor enhances stem cell mobilization, but its high costs and lack of standardized protocol prevent its widespread use. To evaluate the cost-utility of preemptive versus rescue use of plerixafor for hematopoietic stem cell mobilization inMM patients. A Markov model was developed using real-world data from 196 MM patients undergoing stem cell mobilization at two SãoPaulo transplant centers in Brazil. The model compared two strategies: (1) preemptive plerixafor and (2) rescue plerixafor use following mobilization failure. Transition probabilities, utilities, and costs were informed by clinical data and literature. Deterministic and probabilistic sensitivity analyses were performed. The preemptive strategy led to higher rates of successful mobilization and ASCT, resulting in greater quality-adjusted life years (QALYs), but also higher costs. Still, it demonstrated favorable results compared to the rescue approach and passed the Brazilian willingness to pay thresholds of acceptability. Preemptive plerixafor passes the cost-utility guidelines to be used in MM patients in Brazil, potentially guiding policy decisions on resource allocation within the national health system.
DOI: 10.6084/m9.figshare.31047969.v1
title: Cost-utility of pre-emptive plerixafor versus rescue plerixafor in the mobilization of hematopoietic stem cells in multiple myeloma

description: Multiple myeloma (MM) is a hematologic cancer with rising incidence worldwide. Autologous stem cell transplantation (ASCT) is a key treatment for eligible patients, but mobilization failure remains a major obstacle. Plerixafor enhances stem cell mobilization, but its high costs and lack of standardized protocol prevent its widespread use. To evaluate the cost-utility of preemptive versus rescue use of plerixafor for hematopoietic stem cell mobilization inMM patients. A Markov model was developed using real-world data from 196 MM patients undergoing stem cell mobilization at two SãoPaulo transplant centers in Brazil. The model compared two strategies: (1) preemptive plerixafor and (2) rescue plerixafor use following mobilization failure. Transition probabilities, utilities, and costs were informed by clinical data and literature. Deterministic and probabilistic sensitivity analyses were performed. The preemptive strategy led to higher rates of successful mobilization and ASCT, resulting in greater quality-adjusted life years (QALYs), but also higher costs. Still, it demonstrated favorable results compared to the rescue approach and passed the Brazilian willingness to pay thresholds of acceptability. Preemptive plerixafor passes the cost-utility guidelines to be used in MM patients in Brazil, potentially guiding policy decisions on resource allocation within the national health system.
DOI: 10.6084/m9.figshare.31293682
title: T-Consciousness fields alter germination, growth, and biochemical responses of wheat (<i>Triticum aestivum</i> cv. Bahar) under drought stress

description: The existence of consciousness or mind-like properties in plants remains a debated topic in plant biology. This study examined a hypothesis involving nonfrequency T-Consciousness Fields, proposing that information transmitted through these fields may influence plant responses. Using the Faradarmani Consciousness Field (T1) and the T-Consciousness Charge Field (T2), two experiments were conducted in a completely randomized design to assess their effects on wheat (<i>Triticum aestivum</i> cv. Bahar) under drought stress. The germination test was carried out in March, and the subsequent pot experiment was conducted in September 2025 in Gorgan and Guilan Provinces, Iran. In the first experiment, seeds were exposed to PEG-induced drought stress (0, −0.6, and −1.2  MPa) for 8 d, with or without T1 and T2, to evaluate germination and early growth. In the second experiment, seedlings grown in pots were subjected to three weeks of drought by withholding irrigation, with untreated plants serving as controls. Growth parameters, chlorophyll, carotenoid, total protein, and superoxide dismutase (SOD) activities were measured. The results obtained were processed statistically via one-way ANOVA. Severe drought reduced final and mean daily germination by about 40%, whereas T2 significantly improved both (<i>p</i> &lt; 0.05). At −0.6 MPa, shoot and root lengths increased by approximately 70% and 46%, respectively, with significant greater enhancement under T2 (<i>p</i> &lt; 0.05), whereas effects under more severe stress were limited. Under nonstress conditions, T2 markedly increased seedling growth and vigor, with 2–3-fold increases in root and shoot dry weights and 3–4-fold increases in seedling vigor indices compared with those of the control. In the pot experiments, T2 increased shoot length by ~25% and chlorophyll and carotenoid contents by ~60%, while T1 increased protein content by ~25%. Both fields elevated SOD-specific activity by ~50%. Overall, T1 and T2 improved germination, growth, and biochemical traits, indicating their potential to mitigate drought stress in wheat; thus, their application could be recommended as a qualitative strategy to enhance wheat performance under water-limited conditions.
DOI: 10.6084/m9.figshare.31293682.v1
title: T-Consciousness fields alter germination, growth, and biochemical responses of wheat (<i>Triticum aestivum</i> cv. Bahar) under drought stress

description: The existence of consciousness or mind-like properties in plants remains a debated topic in plant biology. This study examined a hypothesis involving nonfrequency T-Consciousness Fields, proposing that information transmitted through these fields may influence plant responses. Using the Faradarmani Consciousness Field (T1) and the T-Consciousness Charge Field (T2), two experiments were conducted in a completely randomized design to assess their effects on wheat (<i>Triticum aestivum</i> cv. Bahar) under drought stress. The germination test was carried out in March, and the subsequent pot experiment was conducted in September 2025 in Gorgan and Guilan Provinces, Iran. In the first experiment, seeds were exposed to PEG-induced drought stress (0, −0.6, and −1.2  MPa) for 8 d, with or without T1 and T2, to evaluate germination and early growth. In the second experiment, seedlings grown in pots were subjected to three weeks of drought by withholding irrigation, with untreated plants serving as controls. Growth parameters, chlorophyll, carotenoid, total protein, and superoxide dismutase (SOD) activities were measured. The results obtained were processed statistically via one-way ANOVA. Severe drought reduced final and mean daily germination by about 40%, whereas T2 significantly improved both (<i>p</i> &lt; 0.05). At −0.6 MPa, shoot and root lengths increased by approximately 70% and 46%, respectively, with significant greater enhancement under T2 (<i>p</i> &lt; 0.05), whereas effects under more severe stress were limited. Under nonstress conditions, T2 markedly increased seedling growth and vigor, with 2–3-fold increases in root and shoot dry weights and 3–4-fold increases in seedling vigor indices compared with those of the control. In the pot experiments, T2 increased shoot length by ~25% and chlorophyll and carotenoid contents by ~60%, while T1 increased protein content by ~25%. Both fields elevated SOD-specific activity by ~50%. Overall, T1 and T2 improved germination, growth, and biochemical traits, indicating their potential to mitigate drought stress in wheat; thus, their application could be recommended as a qualitative strategy to enhance wheat performance under water-limited conditions.
DOI: 10.6084/m9.figshare.31282208
title: LeuO fine-tunes the virulence attributable to <i>Salmonella</i> pathogenicity island-2 via repressing <i>ssrA</i> transcription in <i>Salmonella</i> Typhimurium

description: LeuO, initially identified as a leucine regulator in <i>Escherichia coli</i>, has since been identified as a global regulator required for bacterial pathogenicity in a broad range of bacteria, including <i>Salmonella</i>, <i>Shigella</i>, and <i>Vibrio</i>. This study aimed to determine the regulatory role of LeuO in <i>Salmonella</i> pathogenicity island (SPI)-2, essential for the intracellular proliferation of <i>Salmonella enterica</i> serovar Typhimurium (<i>S</i>. Typhimurium). Overexpression of LeuO repressed the transcription of SPI-2 genes and accordingly decreased its protein levels. Chromatin immunoprecipitation sequencing revealed the genome-wide binding sites of LeuO in <i>S</i>. Typhimurium 14,028 and identified a distinctive 23-nucleotide motif with high similarity to that previously discovered in <i>E. coli</i>. Notably, multiple LeuO-binding sites were predicted within SPI-2, primarily adjacent to the <i>ssrA</i> and <i>ssrB</i> loci. <i>In vitro</i> binding assays verified the high binding affinity between LeuO and three specific motifs located at positions −35 to −12 (<i>ssrA</i><sub><i>1</i></sub>),+231 to + 254 (<i>ssrA</i><sub><i>2</i></sub>) near <i>ssrA</i>, and at positions −622 to −599 (<i>ssrB</i><sub><i>3</i></sub>) near <i>ssrB</i>, relative to their transcription start sites. Furthermore, LeuO overexpression abolished the transcription of <i>lacZ</i> fused to the <i>ssrA</i> promoter containing <i>ssrA</i><sub><i>1</i></sub> and <i>ssrA</i><sub><i>2</i></sub>, suggesting the direct repression of <i>ssrA</i> via LeuO-binding. The absence of LeuO increased the intracellular survival of <i>S</i>. Typhimurium within macrophages, whereas its overexpression attenuated bacterial replication, which was presumably associated with the downregulation of SPI-2 by LeuO. This study reveals the versatile regulatory mechanisms of LeuO and underscores its pivotal role in modulating SPI-2 expression, thereby providing key insights into the fine-tuning of virulence by <i>Salmonella</i> during systemic infection.
DOI: 10.6084/m9.figshare.31282208.v1
title: LeuO fine-tunes the virulence attributable to <i>Salmonella</i> pathogenicity island-2 via repressing <i>ssrA</i> transcription in <i>Salmonella</i> Typhimurium

description: LeuO, initially identified as a leucine regulator in <i>Escherichia coli</i>, has since been identified as a global regulator required for bacterial pathogenicity in a broad range of bacteria, including <i>Salmonella</i>, <i>Shigella</i>, and <i>Vibrio</i>. This study aimed to determine the regulatory role of LeuO in <i>Salmonella</i> pathogenicity island (SPI)-2, essential for the intracellular proliferation of <i>Salmonella enterica</i> serovar Typhimurium (<i>S</i>. Typhimurium). Overexpression of LeuO repressed the transcription of SPI-2 genes and accordingly decreased its protein levels. Chromatin immunoprecipitation sequencing revealed the genome-wide binding sites of LeuO in <i>S</i>. Typhimurium 14,028 and identified a distinctive 23-nucleotide motif with high similarity to that previously discovered in <i>E. coli</i>. Notably, multiple LeuO-binding sites were predicted within SPI-2, primarily adjacent to the <i>ssrA</i> and <i>ssrB</i> loci. <i>In vitro</i> binding assays verified the high binding affinity between LeuO and three specific motifs located at positions −35 to −12 (<i>ssrA</i><sub><i>1</i></sub>),+231 to + 254 (<i>ssrA</i><sub><i>2</i></sub>) near <i>ssrA</i>, and at positions −622 to −599 (<i>ssrB</i><sub><i>3</i></sub>) near <i>ssrB</i>, relative to their transcription start sites. Furthermore, LeuO overexpression abolished the transcription of <i>lacZ</i> fused to the <i>ssrA</i> promoter containing <i>ssrA</i><sub><i>1</i></sub> and <i>ssrA</i><sub><i>2</i></sub>, suggesting the direct repression of <i>ssrA</i> via LeuO-binding. The absence of LeuO increased the intracellular survival of <i>S</i>. Typhimurium within macrophages, whereas its overexpression attenuated bacterial replication, which was presumably associated with the downregulation of SPI-2 by LeuO. This study reveals the versatile regulatory mechanisms of LeuO and underscores its pivotal role in modulating SPI-2 expression, thereby providing key insights into the fine-tuning of virulence by <i>Salmonella</i> during systemic infection.
DOI: 10.15468/dl.ybg4g9
title: Occurrence Download

description: A dataset containing 12896 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Betula nigra"
 ]
}

 The dataset includes 12896 records from 282 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0002563-260208012135463/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.z4v8x5
title: Occurrence Download

description: A dataset containing 5446 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen)"
 ]
 }
 },
 "TaxonKey is Aristida jerichoensis"
 ]
}

 The dataset includes 5446 records from 32 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0002564-260208012135463/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.18037799
title: Battery Imaging Library: SEM NMC811 electrode

description: This entry contains the SEM data for an NMC811 electrode.

If you use these data, then please cite the Battery Imaging Library website and the following paper:

Battery Imaging Library: Multi-length scale and multi-modal synchrotron and laboratory battery imaging data for all, R. Docherty et al., 2025
description: Funding: Royal Society Industry Fellowship IF\R2\222059. The Battery Imaging Library is intended for academic and educational purposes. Commercial use should be discussed with the authors.
DOI: 10.5281/zenodo.18037798
title: Battery Imaging Library: SEM NMC811 electrode

description: This entry contains the SEM data for an NMC811 electrode.

If you use these data, then please cite the Battery Imaging Library website and the following paper:

Battery Imaging Library: Multi-length scale and multi-modal synchrotron and laboratory battery imaging data for all, R. Docherty et al., 2025
description: Funding: Royal Society Industry Fellowship IF\R2\222059. The Battery Imaging Library is intended for academic and educational purposes. Commercial use should be discussed with the authors.