cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.29634149.v1
title: Supplementary Material for: Angiopausin® and Angiopoietin: Unveiling New Mechanisms in Rosacea Treatment through Kinetic Erythema Analysis with the AAREA® Algorithm

description: Introduction: Non-transient erythema (NTE) is a major feature of rosacea, but its clinical evaluation is subject to human investigator variability. The angiopoietin–TIE2 receptor tyrosine kinase pathway plays a key role in regulating vascular homeostasis, but was previously overlooked as a target for rosacea therapy. Angiopausin® is a patented plant-based ingredient identified through a molecular phytotherapy screening program as a positive inducer of the angiopoietin–TIE2 pathway, which is the “gatekeeper of vascular quiescence”. The objective of this preliminary study was to compare traditional clinical NTE scoring methods with a novel algorithm-assisted approach (AAREA®) aimed at both assessing erythema and exploring the potential scientific interest of analyzing erythema regression patterns in patients with rosacea treated with topical Angiopausin. 
Methods: Data were obtained from the regular follow-up of patients with mild-to-moderate rosacea, monitored as part of the real-world, “homeostasis in chronic facial dermatosis” registry cohort. Patients were managed exclusively with Angiopausin (applied twice daily) for up to 64 weeks. Facial redness was evaluated clinically using the global investigator erythema assessment (IEA) score and compared to data generated using the algorithm-assisted approach using an ANOVA with post-hoc Tukey tests. 
Results: Forty-four patients (9 men, 35 women) were included (average follow-up: 29±3 weeks per patient). Reductions in total IEA scores were observed at week 4 (W4; p&lt;0.05) and through W8 to W64 (p&lt;0.001). Decreases in individual scores were also observed for flushing, NTE and edema (W4 to W64: p&lt;0.001), and telangiectasia (W8 to W32; p&lt;0.001). A high level of agreement (R2= 0.9566) was observed between the clinical IEA scores and the algorithm-assisted approach. The algorithm-assisted approach also provided quantitative data on redness area and intensity, detected early reductions in NTE, and identified distinctive NTE regression patterns.
Conclusion: This study demonstrated the real-world effectiveness of targeting the angiopoietin–TIE2 pathway for managing rosacea, with topical Angiopausin resulting in significant and long-lasting reductions in NTE and other vascular manifestations. It also highlighted how advances in rosacea therapy can be studied by profiling the clinical effects of treatments using artificial intelligence. The AAREA tool provided valuable data for clinical scoring and research into understanding rosacea pathogenesis.
DOI: 10.6084/m9.figshare.29634152
title: Supplementary Material for: Mucosal healing of ulcerative colitis based on endoscopic diagnosis, histopathology, and mucosal inflammatory mediators

description: Mucosal healing is necessary to maintain the long-term remission of ulcerative colitis (UC). Currently, the gold standard for assessing mucosal healing is endoscopic diagnosis. The Mayo Endoscopic Subscore (MES) is the most commonly used index for evaluating endoscopic mucosal healing; however, a certain number of patients may experience relapse during the clinical course of the disease, even at MES 0, where the mucosa appears to be in a state of healing. Therefore, the usefulness of image-enhanced endoscopy, such as Narrow-Band Imaging, Linked Color Imaging, Autofluorescence Imaging, Red Dichromatic Imaging, Texture and Color Enhancement Imaging, and i-Scan, has been increasingly reported in recent years for the diagnosis of complete mucosal healing without recurrence. The importance of histological healing has also been emphasized in recent years. The three main histological scoring systems currently used are the Geboes score, Nancy Histological Index, and Robarts Histologic Index. When combined with MES, these histological assessments have been reported to considerably predict UC relapse. However, the relevance of diagnosing histological activity in patients with MES 0 and endoscopically confirmed mucosal healing remains debatable. Cytokines play an important role in UC pathogenesis, as evidenced by the effectiveness of biologics and small molecules that target specific cytokines in treating refractory cases. Therefore, the concept of “molecular healing” has recently been proposed to describe the regulation of cytokine profiles during mucosal healing in patients with UC. Specific mucosal cytokine expression correlates with endoscopic severity, predicts UC relapse, and indicates the therapeutic efficacy of biologics. This highlights the growing interest in understanding UC pathogenesis based on cytokine expression. Defining mucosal healing in UC based on mucosal cytokine expression is expected to evolve as a next-generation diagnostic approach. Therefore, accurate diagnosis of mucosal healing in patients with UC is essential. In this review, we describe mucosal healing from the perspective of mucosal gene expression, which has recently gained attention alongside advances in conventional endoscopic and histological diagnostics.
DOI: 10.6084/m9.figshare.29634152.v1
title: Supplementary Material for: Mucosal healing of ulcerative colitis based on endoscopic diagnosis, histopathology, and mucosal inflammatory mediators

description: Mucosal healing is necessary to maintain the long-term remission of ulcerative colitis (UC). Currently, the gold standard for assessing mucosal healing is endoscopic diagnosis. The Mayo Endoscopic Subscore (MES) is the most commonly used index for evaluating endoscopic mucosal healing; however, a certain number of patients may experience relapse during the clinical course of the disease, even at MES 0, where the mucosa appears to be in a state of healing. Therefore, the usefulness of image-enhanced endoscopy, such as Narrow-Band Imaging, Linked Color Imaging, Autofluorescence Imaging, Red Dichromatic Imaging, Texture and Color Enhancement Imaging, and i-Scan, has been increasingly reported in recent years for the diagnosis of complete mucosal healing without recurrence. The importance of histological healing has also been emphasized in recent years. The three main histological scoring systems currently used are the Geboes score, Nancy Histological Index, and Robarts Histologic Index. When combined with MES, these histological assessments have been reported to considerably predict UC relapse. However, the relevance of diagnosing histological activity in patients with MES 0 and endoscopically confirmed mucosal healing remains debatable. Cytokines play an important role in UC pathogenesis, as evidenced by the effectiveness of biologics and small molecules that target specific cytokines in treating refractory cases. Therefore, the concept of “molecular healing” has recently been proposed to describe the regulation of cytokine profiles during mucosal healing in patients with UC. Specific mucosal cytokine expression correlates with endoscopic severity, predicts UC relapse, and indicates the therapeutic efficacy of biologics. This highlights the growing interest in understanding UC pathogenesis based on cytokine expression. Defining mucosal healing in UC based on mucosal cytokine expression is expected to evolve as a next-generation diagnostic approach. Therefore, accurate diagnosis of mucosal healing in patients with UC is essential. In this review, we describe mucosal healing from the perspective of mucosal gene expression, which has recently gained attention alongside advances in conventional endoscopic and histological diagnostics.
DOI: 10.15468/dl.5vqfs9
title: Occurrence Download

description: A dataset containing 125 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Allium tenuiflorum, Allium montanum, Allium tenuiflorum pseudotenuiflorum, Allium tenuifolium, Allium paniculatum tenoreanum, Allium paniculatum pseudotenuiflorum, Allium pallens tenuiflorum, Allium paniculatum tenuiflorum, Allium paniculatum tenuiflorum, Allium paniculatum tenuiflorum)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "Year is greater than or equal to 2000"
 ]
}

 The dataset includes 125 records from 11 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0037901-250717081556266/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.gtfn34
title: Occurrence Download

description: A dataset containing 3123 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Anthus richardi",
 "MediaType is Image"
 ]
}

 The dataset includes 3123 records from 20 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0037903-250717081556266/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.ucybsj
title: Occurrence Download

description: A dataset containing 608 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is China",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "TaxonKey is Anas poecilorhyncha"
 ]
}

 The dataset includes 608 records from 5 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0037900-250717081556266/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.rf9f52
title: Occurrence Download

description: A dataset containing 866 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Prangos odontalgica"
 ]
}

 The dataset includes 866 records from 42 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0037902-250717081556266/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.h68uf2
title: Occurrence Download

description: A dataset containing 5505 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Scomber australasicus"
 ]
}

 The dataset includes 5505 records from 102 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0037904-250717081556266/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.wwagr5
title: Occurrence Download

description: A dataset containing 960 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "TaxonKey is one of (Desmognathus santeetlah Tilley, 1981)"
 ]
}

 The dataset includes 960 records from 12 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0006421-250426092105405/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.2nhdwa
title: Occurrence Download

description: A dataset containing 35922 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "TaxonKey is one of (Anaxyrus boreas (Baird & Girard, 1852))"
 ]
}

 The dataset includes 35922 records from 69 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0006420-250426092105405/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/zykckd
title: Colección del Laboratorio de Invertebrados del Museo de Historia Natural "Gustavo Orcés V."

description: Esta colección contempla a los invertebrados que componen tanto la colección seca como líquida del Laboratorio y que se encuentran en el Departamento de Biología de la Escuela Politécnica Nacional.
DOI: 10.15468/dl.qsz8mt
title: Occurrence Download

description: A dataset containing 12289 species occurrences available in GBIF matching the query:
{
 "and" : [
 {
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen)"
 ]
 }
 }
 ]
 },
 "TaxonKey is Lysimachia clethroides Duby"
 ]
}

 The dataset includes 12289 records from 179 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0006422-250426092105405/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.15306714
title: cataglyphis_viatica_decontaminated_FSCR.fasta.gz
DOI: 10.5281/zenodo.15306715
title: cataglyphis_viatica_decontaminated_FSCR.fasta.gz
DOI: 10.15468/dl.hg7bq8
title: Occurrence Download

description: A dataset containing 9537 species occurrences available in GBIF matching the query:
{
 "and" : [
 "OccurrenceStatus is Present",
 "TaxonKey is Cedrus atlantica (Endl.) Manetti ex Carriere"
 ]
}

 The dataset includes 9537 records from 386 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0006423-250426092105405/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.jwhev5
title: Occurrence Download

description: A dataset containing 39 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "TaxonKey is one of (Desmognathus valentinei Means, Lamb & Bernardo, 2017)"
 ]
}

 The dataset includes 39 records from 5 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0006424-250426092105405/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.cpxxpg
title: Occurrence Download

description: A dataset containing 1596 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "TaxonKey is one of (Anaxyrus californicus (Camp, 1915))"
 ]
}

 The dataset includes 1596 records from 14 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0006425-250426092105405/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.3535/ajv-svb-wwa
title: Canarium mutabile (Swainson, 1821)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/hse-kly-tf2
title: Marcia hiantina (Lamarck, 1818)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/gl6-bp8-sda
title: Animalia

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/qjf-4k0-5mc
title: Dentalium elephantinum Linnaeus, 1758

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/qw3-9wz-21y
title: Cosmotriphora melanura (C. B. Adams, 1850)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/t9m-84m-66z
title: Animalia

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/zdz-ddx-byv
title: Cypraea tigris Linnaeus, 1758

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/b63-7pl-6az
title: Naria acicularis (Gmelin, 1791)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/kmy-nqr-g64
title: Tridentarius dentatus (Linnaeus, 1758)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/3m9-qqe-p7n
title: Nerita undata Linnaeus, 1758

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/q5v-9sj-d22
title: Ringicula propinquans Hinds, 1844

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/eap-hf8-4np
title: Vexillum plicarium (Linnaeus, 1758)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/y0g-81p-bva
title: Sermyla riquetii (Grateloup, 1840)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/rx1-g4y-vbt
title: Pustularia cicercula (Linnaeus, 1758)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/s0s-n79-1yr
title: Conus achatinus Gmelin, 1791

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/t6l-yle-4k2
title: Barbatia domingensis (Lamarck, 1819)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/4zw-me9-rqr
title: Clanculus Montfort, 1810

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/r7g-8zj-dmv
title: Paratapes textile (Gmelin, 1791)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/ldb-h0e-864
title: Polygona infundibulum (Gmelin, 1791)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/2dh-tds-kd1
title: Pitar obliquatus (Hanley, 1844)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/d41-7pr-4d6
title: Alvania subsoluta (Aradas, 1847)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/0d5-sex-l31
title: Chama asperella Lamarck, 1819

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/rb6-jns-tt5
title: Macrocypraea zebra (Linnaeus, 1758)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/hvy-42r-lzw
title: Colus islandicus (Mohr, 1786)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/2sx-cc2-9rj
title: Animalia

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/ffw-h2f-l0e
title: Euthymella elegans (Hinds, 1843)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/esa-fc2-yv6
title: Lima lima (Linnaeus, 1758)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/k5b-b2g-wbz
title: Nucula calcicola D. R. Moore, 1977

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/6wc-h4f-qsg
title: Monetaria moneta (Linnaeus, 1758)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/1d4-rlp-z69
title: Gibberulus gibbosus (Röding, 1798)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/fqc-5y2-wwt
title: Tucetona pectinata (Gmelin, 1791)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/8xb-6v1-dd3
title: Pseudozonaria annettae (Dall, 1909)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/k6b-nsk-srj
title: Protatlanta souleyeti (E. A. Smith, 1888)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/l1n-das-l42
title: Pustularia margarita (Dillwyn, 1817)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/fbj-4pz-am4
title: Naria spurca (Linnaeus, 1758)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/k99-l8y-8sg
title: Euchelus atratus (Gmelin, 1791)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/bgm-e8m-p3a
title: Tritia corniculum (Olivi, 1792)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/lvv-73t-xtn
title: Mitrella ocellata (Gmelin, 1791)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/vdf-pj7-9va
title: Echinolittorina lineolata (A. d'Orbigny, 1841)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/l57-h4e-t57
title: Glyphoturris quadrata (Reeve, 1845)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/lfr-h37-sk0
title: Lepetella A. E. Verrill, 1880

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/lyv-m9t-0yk
title: Canarium urceus (Linnaeus, 1758)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/07y-bwr-9cn
title: Callista chinensis (Holten, 1802)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/ht8-mzr-rkf
title: Lambis lambis (Linnaeus, 1758)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/87y-sxm-34h
title: Bursa tuberosissima (Reeve, 1844)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/8x4-3ry-tkg
title: Lunarca ovalis (Bruguière, 1789)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/54e-9yl-tll
title: Arcopaginula inflata (Gmelin, 1791)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/kjn-zl0-skd
title: Meropesta sinojaponica Q.-Q. Zhuang, 1983

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/n1z-xqr-gre
title: Oliva tricolor Lamarck, 1811

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/l85-d5l-3js
title: Vexillum moniliferum (C. B. Adams, 1850)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/za8-7m6-vfm
title: Caesia perpinguis (Hinds, 1844)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/r4j-s5w-ppk
title: Bittium incile R. B. Watson, 1897

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/sjc-54q-zpn
title: Bufonaria granosa (K. Martin, 1884)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/lx1-kp3-r7l
title: Clypeomorus batillariaeformis Habe & Kosuge, 1966

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/kqz-zns-qmd
title: Nerita versicolor Gmelin, 1791

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/m29-mrz-lcn
title: Mytilus galloprovincialis Lamarck, 1819

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/9b3-567-lgj
title: Mauritia arabica arabica (Linnaeus, 1758)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/d33-k2h-kqh
title: Littorina obtusata (Linnaeus, 1758)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/cy5-s6m-n2t
title: Aspa marginata (Gmelin, 1791)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/7dq-pbm-7xy
title: Naria marginalis (Dillwyn, 1827)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.