cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.11314670.v1
title: Defending entitlement: struggles and fate of the practice of homeopathy in Colombia (1905-1950)

description: Abstract This article analyzes the practice and professional status of Colombian homeopaths in the twentieth century, based on applications for licenses in the “Teguas” series in the Archivo General de la Nación. Within the historical context of the practice of medicine in Colombia, it studies homeopathic practice within the framework of the debate between licensed and permitted medicine. In that context, the field of homeopathy was subordinate to university medicine and homeopaths were a group of practitioners who were neither homogeneous nor organized, but characterized by their shared struggle to become “entitled” to practice, and their advocacy of professional status through constant litigation against official reprimands.
DOI: 10.6084/m9.figshare.11314652
title: Practical rules for summing the series of the Tweedie probability density function with high-precision arithmetic

description: Abstract: For some ranges of its parameters and arguments, the series for Tweedie probability density functions are sometimes exceedingly difficult to sum numerically. Existing numerical implementations utilizing inversion techniques and properties of stable distributions can cope with these problems, but no single one is successful in all cases. In this work we investigate heuristically the nature of the problem, and show that it is not related to the order of summation of the terms. Using a variable involved in the analytical proof of convergence of the series, the critical parameter for numerical non-convergence (“alpha”) is identified, and an heuristic criterion is developed to avoid numerical non-convergence for a reasonably large sub-interval of the latter. With these practical rules, simple summation algorithms provide sufficiently robust results for the calculation of the density function and its definite integrals. These implementations need to utilize high-precision arithmetic, and are programmed in the Python programming language. A thorough comparison with existing R functions allows the identification of cases when the latter fail, and provide further guidance to their use.
DOI: 10.6084/m9.figshare.11314655
title: Analysis of Electronic Apex Locators in Human Teeth Diagnosed With Apical Periodontitis

description: Abstract Electronic apex locators (EAL) have been used to establish the working length (WL) in root canal treatment. In teeth diagnosed with apical periodontitis, resorption of tooth apical structures can lead to difficulties to obtain an appropriate WL. The aim was to compare the capacity of three EAL’s (Root ZX II, Raypex 6 and Endo-Eze Quill) to locate the tip of the K-file between 0 to -0.5 mm from the apical foramen (AF) on teeth diagnosed with asymptomatic apical periodontitis (AAP). Electronic working length was performed on 60 roots with AAP. A K-file #15 was inserted in the root canal until the apical foramen (AF) was located, and followed was re-adjusted to -0.5 mm through observation in EAL display. The K-file was fixed to the tooth with composite and teeth were extracted. The 4 apical millimeters were worn out until the K-file could be seen and were prepared and measured its distance to AF in a scanning electron microscope. Appropriate WL was when the tip of the K-file was located between 0 to -0.5 mm from AF. Results: Root ZX II showed significant difference (p&lt;0.01) with the other two EALs. Root ZX II presented the better performance than Raypex 6 or Endo-Eze Quill in teeth with AAP.
DOI: 10.6084/m9.figshare.11314658.v1
title: A Rare Cause of Angina After Coronary Bypass Grafting; Left İnternal Mammary Artery to Pulmonary Artery Fistula and Successful Treatment with Transcatheter Coil Embolization

description: Abstract Fistula from left internal mammary artery (LIMA) to pulmonary artery (PA) is rarely encountered in daily practice. In recent years, endovascular therapy options have emerged for the treatment of fistula formations and replaced with surgery. A 53-year-old man admitted to our outpatient clinic with symptoms of typical angina and shortness of breath despite optimal medical therapy. In his relevant history, he had a coronary artery bypass graft (CABG) operation in 2009 in which his LIMA was anastomosed to left anterior descending (LAD) and ramus artery sequentially. Coronary angiography including selective imaging of LIMA demonstrated a fistula formation originating from the proximal portion of the LIMA and draining to PA. After successful closure of fistula with transcatheter coil embolization, the patient was discharged without any complication and symptom. In conclusion, although LIMA to PA fistula is an infrequent clinical condition, it should be considered as a potential cause of persistent angina after CABG operation. Treatment options include conservative medical therapy, surgical ligation and endovascular interventions. The best therapy should be individualised for each patient in respect to patient’s symptoms, surgical compatibility and anatomy of fistula.
DOI: 10.6084/m9.figshare.11314661.v1
title: Effects of long-term controlled internal drug release reuse on reproductive performance, hormone profiles, and economic profit of sheep

description: ABSTRACT Fifty-seven multiparous Awassi ewes in the breeding season were used to compare the effects of controlled internal drug release (CIDR) reuse on hormone profiles, reproductive performance, and economic production. Ewes were randomly allotted to one of three CIDR treatments: new (control), once-used, and twice-used; treatment lasted 12 days. Blood samples were collected from all groups at the time of CIDR insertion, three and six days following insertion, at withdrawal time, and at insemination. Serum estradiol (E2) and progesterone (P4) concentrations were measured. Timed insemination was performed 48 h post CIDR withdrawal in all groups. Pregnancy was diagnosed by ultrasonography at day 23 post insemination. No significant differences were detected among groups in pregnancy rate/ewes in heat, twinning rate, fecundity, abortion rate, and prolificacy. However, estrus detection rate was significantly higher in control (100%) than in other groups. The P4 concentration was significantly higher in control than in other groups during treatment period; at insemination, P4 concentration was significantly higher in control than in other groups; at insemination time, E2 concentration was significantly higher in control than in the other groups; and the net profit was higher in once-used than in other groups. One-time reuse of CIDR for the long term (12 days) can synchronize estrus in ewes efficiently with higher net profit than the new or twice-used CIDR.
DOI: 10.6084/m9.figshare.11314646
title: Protective efficacy of combined use of parecoxib and dexmedetomidine on postoperative hyperalgesia and early cognitive dysfunction after laparoscopic cholecystectomy for elderly patients

description: Abstract Purpose: To investigate efficacy of combined use of parecoxib and dexmedetomidine on postoperative pain and early cognitive dysfunction after laparoscopic cholecystectomy for elderly patients. Methods: The present prospective randomized controlled study included a total of 80 patients who underwent laparoscopic cholecystectomy surgery during January 2016 to November 2017 in our hospital. All patients were randomly divided into 4 groups, the parecoxib group, the dexmedetomidine group, the parecoxib and dexmedetomidine combined group, and the control group. Demographic data and clinical data were collected. Indexes of heart rate (HR), mean arterial pressure (MAP), levels of jugular venous oxygen saturation (SjvO2) and jugular venous oxygen pressure (PjvO2) were recorded at different time points before and during the surgery. The mini-mental state examination (MMSE) score, Ramsay score and Visual Analogue Score (VAS) were measured. Results: Levels of both SjvO2 and PjvO2 were significantly higher in parecoxib group, dexmedetomidine group and the combined group than the control group. Meanwhile, levels of both SjvO2 and PjvO2 in the combined group were the highest. VAS scores were significantly lower in the combined group than all other groups, and total patient controlled intravenous analgesia (PCIA) pressing times within 48 h after surgery were the lowest in the combined group. Both Ramsay and MMSE scores were the highest in the combined group compared with other groups, while were the lowest in the control group. Conclusion: The combined use of parecoxib and dexmedetomidine could reduce the postoperative pain and improve the postoperative sedation and cognitive conditions of patients after laparoscopic cholecystectomy.
DOI: 10.6084/m9.figshare.11314655.v1
title: Analysis of Electronic Apex Locators in Human Teeth Diagnosed With Apical Periodontitis

description: Abstract Electronic apex locators (EAL) have been used to establish the working length (WL) in root canal treatment. In teeth diagnosed with apical periodontitis, resorption of tooth apical structures can lead to difficulties to obtain an appropriate WL. The aim was to compare the capacity of three EAL’s (Root ZX II, Raypex 6 and Endo-Eze Quill) to locate the tip of the K-file between 0 to -0.5 mm from the apical foramen (AF) on teeth diagnosed with asymptomatic apical periodontitis (AAP). Electronic working length was performed on 60 roots with AAP. A K-file #15 was inserted in the root canal until the apical foramen (AF) was located, and followed was re-adjusted to -0.5 mm through observation in EAL display. The K-file was fixed to the tooth with composite and teeth were extracted. The 4 apical millimeters were worn out until the K-file could be seen and were prepared and measured its distance to AF in a scanning electron microscope. Appropriate WL was when the tip of the K-file was located between 0 to -0.5 mm from AF. Results: Root ZX II showed significant difference (p&lt;0.01) with the other two EALs. Root ZX II presented the better performance than Raypex 6 or Endo-Eze Quill in teeth with AAP.
DOI: 10.6084/m9.figshare.11314640
title: Utilization of Uncaria gambir Roxb filtrate in the formation of bioactive edible films based on corn starch

description: Abstract The objective of this research was to determine the effect of Uncaria gambir Roxb filtrate addition on functional edible films based on corn starch. This study used a Factorial Randomized Completely Design with two treatments and three replication for each treatment. The first factor was the concentration of Uncaria gambir Roxb filtrate (20%, 30%, 40%) and the second factor was the mixing separation method (filtering, centrifuge 1000 rpm, centrifuge 2000 rpm). The results showed that treatment of Uncaria gambir Roxb filtrate and the mixing separation method had significant effect on thickness, elongation percentage, water vapour transmission rate, antioxidant and antibacterial activities of edible film. The interaction of Uncaria gambir Roxb filtrate and the mixing separation method had significant effect on water vapour transmission rate. The best treatment based on edible film characteristics was 40% concentration of Uncaria gambir Roxb filtrate and the mixed separation method of 1000 rpm centrifugation.
DOI: 10.6084/m9.figshare.11314646.v1
title: Protective efficacy of combined use of parecoxib and dexmedetomidine on postoperative hyperalgesia and early cognitive dysfunction after laparoscopic cholecystectomy for elderly patients

description: Abstract Purpose: To investigate efficacy of combined use of parecoxib and dexmedetomidine on postoperative pain and early cognitive dysfunction after laparoscopic cholecystectomy for elderly patients. Methods: The present prospective randomized controlled study included a total of 80 patients who underwent laparoscopic cholecystectomy surgery during January 2016 to November 2017 in our hospital. All patients were randomly divided into 4 groups, the parecoxib group, the dexmedetomidine group, the parecoxib and dexmedetomidine combined group, and the control group. Demographic data and clinical data were collected. Indexes of heart rate (HR), mean arterial pressure (MAP), levels of jugular venous oxygen saturation (SjvO2) and jugular venous oxygen pressure (PjvO2) were recorded at different time points before and during the surgery. The mini-mental state examination (MMSE) score, Ramsay score and Visual Analogue Score (VAS) were measured. Results: Levels of both SjvO2 and PjvO2 were significantly higher in parecoxib group, dexmedetomidine group and the combined group than the control group. Meanwhile, levels of both SjvO2 and PjvO2 in the combined group were the highest. VAS scores were significantly lower in the combined group than all other groups, and total patient controlled intravenous analgesia (PCIA) pressing times within 48 h after surgery were the lowest in the combined group. Both Ramsay and MMSE scores were the highest in the combined group compared with other groups, while were the lowest in the control group. Conclusion: The combined use of parecoxib and dexmedetomidine could reduce the postoperative pain and improve the postoperative sedation and cognitive conditions of patients after laparoscopic cholecystectomy.
DOI: 10.6084/m9.figshare.11314652.v1
title: Practical rules for summing the series of the Tweedie probability density function with high-precision arithmetic

description: Abstract: For some ranges of its parameters and arguments, the series for Tweedie probability density functions are sometimes exceedingly difficult to sum numerically. Existing numerical implementations utilizing inversion techniques and properties of stable distributions can cope with these problems, but no single one is successful in all cases. In this work we investigate heuristically the nature of the problem, and show that it is not related to the order of summation of the terms. Using a variable involved in the analytical proof of convergence of the series, the critical parameter for numerical non-convergence (“alpha”) is identified, and an heuristic criterion is developed to avoid numerical non-convergence for a reasonably large sub-interval of the latter. With these practical rules, simple summation algorithms provide sufficiently robust results for the calculation of the density function and its definite integrals. These implementations need to utilize high-precision arithmetic, and are programmed in the Python programming language. A thorough comparison with existing R functions allows the identification of cases when the latter fail, and provide further guidance to their use.
DOI: 10.6084/m9.figshare.11314637
title: Does Cystatin C have a role as metabolic surrogate in peritoneal dialysis beyond its association with residual renal function?

description: ABSTRACT Introduction: It has been suggested that cystatin C levels are modified by obesity and inflammation. Furthermore, cystatin C has been associated with cardiovascular events and mortality outcomes. Aim: To study the association of cystatin C with the metabolic profile and cardiovascular disease of peritoneal dialysis patients. Methods: Data collected included clinical, laboratorial, and multifrequency bioimpedance assessment of 52 stable peritoneal dialysis patients. Minimal residual renal function was defined as &gt; 2mL/min/1.73m2. Results: Serum cystatin C was not significantly associated with peritoneal or urinary cystatin C excretion. Negative correlation of cystatin C with normalized protein catabolic rate (rho -0.33, p = 0.02) and a trend towards positive correlation with relative body fat (rho 0.27, p = 0.05) were not independent from residual renal function. Cystatin C was not significantly associated with cardiovascular disease (p = 0.28), nor with glycated hemoglobin (p = 0.19) or c-reactive protein (p = 0.56). In the multivariate model, both age and diabetes were the strongest predictors of cardiovascular disease (odds ratio 1.09, p = 0.029 and odds ratio 29.95, p = 0.016, respectively), while relative body fat was negatively associated with cardiovascular disease (p = 0.038); neither cystatin C (p = 0.096) nor minimal residual renal function (p = 0.756) reached a significant association with cardiovascular disease. Conclusions: In this group of peritoneal dialysis patients, cystatin C did not correlate with the metabolic or inflammatory status, nor cardiovascular disease, after adjustment for residual renal function.
DOI: 10.6084/m9.figshare.11314631
title: Forage potential of native ecotypes of Paspalum notatum and P. guenoarum

description: ABSTRACT The Paspalum genus includes several species that are important for livestock in Rio Grande do Sul, such as P. notatum and P. guenoarum, typical of native pastures of the Pampa biome. The aim of this study was to investigate forage production and chemical composition of four ecotypes of these species in relation to the cv. ‘Pensacola’ (P. notatum). Ecotypes of P. guenoarum (Azulão and Baio) and P. notatum (André da Rocha and Bagual) and the cv. ‘Pensacola’ were evaluated for two years, during which four cuts/year were made. The work was carried out under field conditions at the Agronomic Experimental Station of the Federal University of Rio Grande do Sul (30°05’S; 51°39’W), in a completely randomized design. P. guenoarum stood out for higher productivity and greater tolerance to cold; the Azulão ecotype showed more autumn production in relation to the other ecotypes. Crude protein content ranged from 14 (Baio) to 15% (‘Pensacola’); for neutral detergent fiber, the variation was 68 (Azulão) to 71% (‘Pensacola’) and for acid detergent fiber there was a variation of 38 (‘Pensacola’) to 43% (Baio). The data demonstrates the potential of native genotypes for use as cattle feeding in southern Brazil.
DOI: 10.6084/m9.figshare.11314634
title: Effect of resin content and pressing temperature on banana pseudo-stem particle boards properties using full factorial design

description: Abstract: The volume of global gross banana exports reached a record of 117.9 million tonnes in 2015 (FAO 2017), which agro-industrial wastes derived as the pseudo-stem, rachis and leaves do not have an industrial application instead they are discarded. This research study applies full factorial design and response surface methodology to determine the effect of pressing temperature and resin content on density (D), moisture (M), water absorption (WA), water swelling (WS), module of rupture (MOR), module of elasticity (MOE) and formaldehyde content (FC) of particle board made of banana pseudo-stem. A 22 factorial design was performed, factors considered were resin and temperature. The low level of resin was 15% in the coarse fiber (CF) and 35% in fine fiber (FF); high level as 25% CF and 45% FF. Temperature levels were 150ºC and 170ºC respectively. The boards met all quality parameters except ones with low resin content that didn’t meet WS parameter. Furthermore, resin affected positively on WA, FC and MOE, and decreased D, WS and MOR values. Meanwhile, temperature affected negatively on D, WS, and increased FC, WA, MOE, MOR properties; none of the factors affected M response. Process conditions were optimized to 162.61°C and 43.15% FF, 23.97% CF.
DOI: 10.6084/m9.figshare.11314640.v1
title: Utilization of Uncaria gambir Roxb filtrate in the formation of bioactive edible films based on corn starch

description: Abstract The objective of this research was to determine the effect of Uncaria gambir Roxb filtrate addition on functional edible films based on corn starch. This study used a Factorial Randomized Completely Design with two treatments and three replication for each treatment. The first factor was the concentration of Uncaria gambir Roxb filtrate (20%, 30%, 40%) and the second factor was the mixing separation method (filtering, centrifuge 1000 rpm, centrifuge 2000 rpm). The results showed that treatment of Uncaria gambir Roxb filtrate and the mixing separation method had significant effect on thickness, elongation percentage, water vapour transmission rate, antioxidant and antibacterial activities of edible film. The interaction of Uncaria gambir Roxb filtrate and the mixing separation method had significant effect on water vapour transmission rate. The best treatment based on edible film characteristics was 40% concentration of Uncaria gambir Roxb filtrate and the mixed separation method of 1000 rpm centrifugation.
DOI: 10.6084/m9.figshare.11314628
title: A possible relationship between gluconeogenesis and glycogen metabolism in rabbits during myocardial ischemia

description: ABSTRACT Ischemia is responsible for many metabolic abnormalities in the heart, causing changes in organ function. One of modifications occurring in the ischemic cell is changing from aerobic to anaerobic metabolism. This change causes the predominance of the use of carbohydrates as an energy substrate instead of lipids. In this case, the glycogen is essential to the maintenance of heart energy intake, being an important reserve to resist the stress caused by hypoxia, using glycolysis and lactic acid fermentation. In order to study the glucose anaerobic pathways utilization and understand the metabolic adaptations, New Zealand white rabbits were subjected to ischemia caused by Inflow occlusion technique. The animals were monitored during surgery by pH and lactate levels. Transcription analysis of the pyruvate kinase, lactate dehydrogenase and phosphoenolpyruvate carboxykinase enzymes were performed by qRT-PCR, and glycogen quantification was determined enzymatically. Pyruvate kinase transcription increased during ischemia, followed by glycogen consumption content. The gluconeogenesis increased in control and ischemia moments, suggesting a relationship between gluconeogenesis and glycogen metabolism. This result shows the significant contribution of these substrates in the organ energy supply and demonstrates the capacity of the heart to adapt the metabolism after this injury, sustaining the homeostasis during short-term myocardial ischemia.
DOI: 10.6084/m9.figshare.11314634.v1
title: Effect of resin content and pressing temperature on banana pseudo-stem particle boards properties using full factorial design

description: Abstract: The volume of global gross banana exports reached a record of 117.9 million tonnes in 2015 (FAO 2017), which agro-industrial wastes derived as the pseudo-stem, rachis and leaves do not have an industrial application instead they are discarded. This research study applies full factorial design and response surface methodology to determine the effect of pressing temperature and resin content on density (D), moisture (M), water absorption (WA), water swelling (WS), module of rupture (MOR), module of elasticity (MOE) and formaldehyde content (FC) of particle board made of banana pseudo-stem. A 22 factorial design was performed, factors considered were resin and temperature. The low level of resin was 15% in the coarse fiber (CF) and 35% in fine fiber (FF); high level as 25% CF and 45% FF. Temperature levels were 150ºC and 170ºC respectively. The boards met all quality parameters except ones with low resin content that didn’t meet WS parameter. Furthermore, resin affected positively on WA, FC and MOE, and decreased D, WS and MOR values. Meanwhile, temperature affected negatively on D, WS, and increased FC, WA, MOE, MOR properties; none of the factors affected M response. Process conditions were optimized to 162.61°C and 43.15% FF, 23.97% CF.