cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.10042379.v1
title: Voltage vs. Ligand I: Structural basis of the intrinsic flexibility of S3 segment and its significance in ion channel activation

description: We systematically predict the internal flexibility of the S3 segment, one of the most mobile elements in the voltage-sensor domain. By analyzing the primary amino acid sequences of V-sensor containing proteins, including Hv1, TPC channels and the voltage-sensing phosphatases, we established correlations between the local flexibility and modes of activation for different members of the VGIC superfamily. Taking advantage of the structural information available, we also assessed structural aspects to understand the role played by the flexibility of S3 during the gating of the pore. We found that S3 flexibility is mainly determined by two specific regions: (1) a short NxxD motif in the N-half portion of the helix (S3a), and (2) a short sequence at the beginning of the so-called <i>paddle</i> motif where the segment has a kink that, in some cases, divide S3 into two distinct helices (S3a and S3b). A good correlation between the flexibility of S3 and the reported sensitivity to temperature and mechanical stretch was found. Thus, if the channel exhibits high sensitivity to heat or membrane stretch, local S3 flexibility is low. On the other hand, high flexibility of S3 is preferentially associated to channels showing poor heat and mechanical sensitivities. In contrast, we did not find any apparent correlation between S3 flexibility and voltage or ligand dependence. Overall, our results provide valuable insights into the dynamics of channel-gating and its modulation.
DOI: 10.6084/m9.figshare.10042343
title: circular_contigs_human_gut

description: circular contigs from human gut metagenomes
DOI: 10.6084/m9.figshare.10042343.v1
title: circular_contigs_human_gut

description: circular contigs from human gut metagenomes
DOI: 10.6084/m9.figshare.10042328
title: <i>Plasmopara viticola</i> effector PvRXLR159 suppresses immune responses in <i>Nicotiana benthamiana</i>

description: <i>Plasmopara viticola</i>, the causal oomycete of grapevine downy mildew disease, secrets a series of RXLR effectors to manipulate host immunity. In this study, we characterized the role of a RXLR effector of <i>P. viticola</i>, PvRXLR159, in plant–microbe interaction. Transcription of <i>PvRXLR159</i> in <i>P. viticola</i> was induced in the early stage of infection in grapevine (<i>Vitis vinifera</i> ‘Thomson Seedless’). Further results revealed that PvRXLR159 contains a functional signal peptide and its C terminus was essential to inhibit cell death by elicitors, INF1 and BAX, in <i>Nicotiana benthamiana</i>. Transient expression of PvRXLR159 suppressed <i>N. benthamiana</i> resistance to a pathogenic oomycete, <i>Phytophthora capsici</i>. Taken together, we propose that PvRXLR159 is induced and secreted by <i>P. viticola</i> to suppress host resistance.
DOI: 10.6084/m9.figshare.10042331
title: The identification of active compounds in <i>Ganoderma lucidum var. antler</i> extract inhibiting dengue virus serine protease and its computational studies

description: The number of global dengue incidences is alarmingly high in recent years. The global distribution of four dengue serotypes has also added economic burden in the dengue-endemic countries. To discover the potent dengue virus inhibitors in the antler form of <i>Ganoderma lucidum</i> (Lingzhi or Reishi), the water extraction of normal <i>G. lucidum</i> and its antler form were conducted and the chemical compounds were identified by LC-MS. Six distinct chemical compounds identified in high abundance were hesperetin, thymidine, lucidenic acid, 11-aminoundecanoic acid, 5-carboxyvanillic acid and ganocin B. The water extracts of <i>G. lucidum</i> in its antler form inhibited the DENV2 NS2B-NS3 protease activity at 84.6 ± 0.7%, higher than the normal <i>G. lucidum</i>. Then, molecular docking was performed on the homology model built from an in-house sequence. Docking simulation results showed that hesperetin and ganocin B were the best leads to bind at the catalytic triad of DENV2 NS2B-NS3pro via hydrogen bonding, van der Waals and pi-pi interactions. Extensive overlapping of HOMO-LUMO orbitals at the ringed regions of hesperetin helped to facilitate the entry of ligand to the catalytic triad cleft. LC-MS, molecular docking and density functional theory analyses confirmed that hesperetin was the strongest inhibitor against NS2B-NS3 protease. Communicated by Ramaswamy H. Sarma
DOI: 10.6084/m9.figshare.10042325
title: Effect of salt supplementation on sympathetic activity and endothelial function in salt sensitive type 2 diabetes: Comparison of raw values of MSNA, EndoPAT and cardiac baroreflex post placebo and post salt intervention

description: Raw values of MSNA, endoPAT ad cardiac baroreflex post salt supplementation and post placebo
DOI: 10.6084/m9.figshare.10042325.v1
title: Effect of salt supplementation on sympathetic activity and endothelial function in salt sensitive type 2 diabetes: Comparison of raw values of MSNA, EndoPAT and cardiac baroreflex post placebo and post salt intervention

description: Raw values of MSNA, endoPAT ad cardiac baroreflex post salt supplementation and post placebo
DOI: 10.6084/m9.figshare.10042328.v1
title: <i>Plasmopara viticola</i> effector PvRXLR159 suppresses immune responses in <i>Nicotiana benthamiana</i>

description: <i>Plasmopara viticola</i>, the causal oomycete of grapevine downy mildew disease, secrets a series of RXLR effectors to manipulate host immunity. In this study, we characterized the role of a RXLR effector of <i>P. viticola</i>, PvRXLR159, in plant–microbe interaction. Transcription of <i>PvRXLR159</i> in <i>P. viticola</i> was induced in the early stage of infection in grapevine (<i>Vitis vinifera</i> ‘Thomson Seedless’). Further results revealed that PvRXLR159 contains a functional signal peptide and its C terminus was essential to inhibit cell death by elicitors, INF1 and BAX, in <i>Nicotiana benthamiana</i>. Transient expression of PvRXLR159 suppressed <i>N. benthamiana</i> resistance to a pathogenic oomycete, <i>Phytophthora capsici</i>. Taken together, we propose that PvRXLR159 is induced and secreted by <i>P. viticola</i> to suppress host resistance.
DOI: 10.6084/m9.figshare.10042319
title: Cognitive bias and perseverance

description: Behavioral data from an experiment of reinforcement learning in humans.
DOI: 10.6084/m9.figshare.10042319.v1
title: Cognitive bias and perseverance

description: Behavioral data from an experiment of reinforcement learning in humans (R file).
DOI: 10.6084/m9.figshare.10042244
title: MOESM6 of The minimal kinome of Giardia lamblia illuminates early kinase evolution and unique parasite biology

description: Additional file 6: Alignment S1. Nek kinase domain alignment. (ALN 580 KB)
DOI: 10.6084/m9.figshare.10042238
title: MOESM4 of The minimal kinome of Giardia lamblia illuminates early kinase evolution and unique parasite biology

description: Additional file 4: Table S3. Definition of domain names and abbreviations. (XLS 55 KB)
DOI: 10.6084/m9.figshare.10042244.v1
title: MOESM6 of The minimal kinome of Giardia lamblia illuminates early kinase evolution and unique parasite biology

description: Additional file 6: Alignment S1. Nek kinase domain alignment. (ALN 580 KB)
DOI: 10.6084/m9.figshare.10042238.v1
title: MOESM4 of The minimal kinome of Giardia lamblia illuminates early kinase evolution and unique parasite biology

description: Additional file 4: Table S3. Definition of domain names and abbreviations. (XLS 55 KB)
DOI: 10.6084/m9.figshare.10042229
title: MOESM1 of The minimal kinome of Giardia lamblia illuminates early kinase evolution and unique parasite biology

description: Additional file 1: Table S1. Detailed annotation of all kinases in all three strains, including sequences, SAGE expression, classification, and catalytic ability. (XLS 1 MB)
DOI: 10.6084/m9.figshare.10042235
title: MOESM3 of The minimal kinome of Giardia lamblia illuminates early kinase evolution and unique parasite biology

description: Additional file 3: Table S2. Draft kinomes of Trichomonas vaginalis and Leishmania major. (XLS 1 MB)
DOI: 10.6084/m9.figshare.10042235.v1
title: MOESM3 of The minimal kinome of Giardia lamblia illuminates early kinase evolution and unique parasite biology

description: Additional file 3: Table S2. Draft kinomes of Trichomonas vaginalis and Leishmania major. (XLS 1 MB)
DOI: 10.6084/m9.figshare.10042229.v1
title: MOESM1 of The minimal kinome of Giardia lamblia illuminates early kinase evolution and unique parasite biology

description: Additional file 1: Table S1. Detailed annotation of all kinases in all three strains, including sequences, SAGE expression, classification, and catalytic ability. (XLS 1 MB)
DOI: 10.6084/m9.figshare.10042199
title: of The minimal kinome of Giardia lamblia illuminates early kinase evolution and unique parasite biology

description: of The minimal kinome of Giardia lamblia illuminates early kinase evolution and unique parasite biology
DOI: 10.6084/m9.figshare.10042199.v1
title: of The minimal kinome of Giardia lamblia illuminates early kinase evolution and unique parasite biology

description: of The minimal kinome of Giardia lamblia illuminates early kinase evolution and unique parasite biology
DOI: 10.6084/m9.figshare.10042193
title: of The minimal kinome of Giardia lamblia illuminates early kinase evolution and unique parasite biology

description: of The minimal kinome of Giardia lamblia illuminates early kinase evolution and unique parasite biology
DOI: 10.6084/m9.figshare.10042184
title: of The minimal kinome of Giardia lamblia illuminates early kinase evolution and unique parasite biology

description: of The minimal kinome of Giardia lamblia illuminates early kinase evolution and unique parasite biology
DOI: 10.6084/m9.figshare.10042193.v1
title: of The minimal kinome of Giardia lamblia illuminates early kinase evolution and unique parasite biology

description: of The minimal kinome of Giardia lamblia illuminates early kinase evolution and unique parasite biology
DOI: 10.6084/m9.figshare.10042190
title: of The minimal kinome of Giardia lamblia illuminates early kinase evolution and unique parasite biology

description: of The minimal kinome of Giardia lamblia illuminates early kinase evolution and unique parasite biology
DOI: 10.6084/m9.figshare.10042184.v1
title: of The minimal kinome of Giardia lamblia illuminates early kinase evolution and unique parasite biology

description: of The minimal kinome of Giardia lamblia illuminates early kinase evolution and unique parasite biology
DOI: 10.6084/m9.figshare.10042190.v1
title: of The minimal kinome of Giardia lamblia illuminates early kinase evolution and unique parasite biology

description: of The minimal kinome of Giardia lamblia illuminates early kinase evolution and unique parasite biology
DOI: 10.6084/m9.figshare.10042094
title: MOESM3 of Very low sensitivity of wet mount microscopy compared to PCR against culture in the diagnosis of vaginal trichomoniasis in Uganda: a cross sectional study

description: Additional file 3. Dataset analyzed for sensitivity and specificity of WMM and in-house PCR.
DOI: 10.6084/m9.figshare.10042094.v1
title: MOESM3 of Very low sensitivity of wet mount microscopy compared to PCR against culture in the diagnosis of vaginal trichomoniasis in Uganda: a cross sectional study

description: Additional file 3. Dataset analyzed for sensitivity and specificity of WMM and in-house PCR.
DOI: 10.6084/m9.figshare.10042073
title: of Recurrent evolution of heat-responsiveness in Brassicaceae COPIA elements

description: of Recurrent evolution of heat-responsiveness in Brassicaceae COPIA elements
DOI: 10.6084/m9.figshare.10042076
title: of Recurrent evolution of heat-responsiveness in Brassicaceae COPIA elements

description: of Recurrent evolution of heat-responsiveness in Brassicaceae COPIA elements
DOI: 10.6084/m9.figshare.10042070
title: of Recurrent evolution of heat-responsiveness in Brassicaceae COPIA elements

description: of Recurrent evolution of heat-responsiveness in Brassicaceae COPIA elements
DOI: 10.6084/m9.figshare.10042073.v1
title: of Recurrent evolution of heat-responsiveness in Brassicaceae COPIA elements

description: of Recurrent evolution of heat-responsiveness in Brassicaceae COPIA elements
DOI: 10.6084/m9.figshare.10042076.v1
title: of Recurrent evolution of heat-responsiveness in Brassicaceae COPIA elements

description: of Recurrent evolution of heat-responsiveness in Brassicaceae COPIA elements
DOI: 10.6084/m9.figshare.10042067
title: of Recurrent evolution of heat-responsiveness in Brassicaceae COPIA elements

description: of Recurrent evolution of heat-responsiveness in Brassicaceae COPIA elements
DOI: 10.6084/m9.figshare.10042058
title: of Recurrent evolution of heat-responsiveness in Brassicaceae COPIA elements

description: of Recurrent evolution of heat-responsiveness in Brassicaceae COPIA elements
DOI: 10.6084/m9.figshare.10042061
title: of Recurrent evolution of heat-responsiveness in Brassicaceae COPIA elements

description: of Recurrent evolution of heat-responsiveness in Brassicaceae COPIA elements
DOI: 10.6084/m9.figshare.10042070.v1
title: of Recurrent evolution of heat-responsiveness in Brassicaceae COPIA elements

description: of Recurrent evolution of heat-responsiveness in Brassicaceae COPIA elements
DOI: 10.6084/m9.figshare.10042055
title: of Recurrent evolution of heat-responsiveness in Brassicaceae COPIA elements

description: of Recurrent evolution of heat-responsiveness in Brassicaceae COPIA elements
DOI: 10.6084/m9.figshare.10042058.v1
title: of Recurrent evolution of heat-responsiveness in Brassicaceae COPIA elements

description: of Recurrent evolution of heat-responsiveness in Brassicaceae COPIA elements
DOI: 10.17632/4y8s925fkm.2
title: Pre-processing of drought/water stress detection chlorophyll fluorescence wheat images for efficient segmentation

description: The data consist of a file system-based data of Raj 3765  variety of wheat. There are twenty-four chlorophyll fluorescence images  (Control and Drought) that have been captured for a period of sixty days. A total of (1440 x 2) images are used for this research work.

The generated chlorophyll fluorescence set is subjected to various pre-processing operations including noise removal, contrast enhancement. Pre-processed images are subjected to segmentation to increase water stress detection accuracy for automation
DOI: 10.17632/4y8s925fkm.3
title: Pre-processing of drought/water stress detection chlorophyll fluorescence wheat images for efficient segmentation

description: The data consist of a file system-based data of Raj 3765  variety of wheat. There are twenty-four chlorophyll fluorescence images  (Control and Drought) that have been captured for a period of sixty days. A total of (1440 x 2) images are used for this research work.

The generated chlorophyll fluorescence set is subjected to various pre-processing operations including noise removal, and contrast enhancement. Pre-processed images are subjected to segmentation to increase water stress detection accuracy for automation
DOI: 10.17632/4y8s925fkm.1
title: Pre-processing of drought/water stress detection chlorophyll fluorescence images for efficient segmentation

description: The data consist of a file system-based data of Raj 3765  variety of wheat. There are twenty-four chlorophyll fluorescence images  (Control and Drought) that have been captured for a period of sixty days. A total of (1440 x 2) images are used for this research work.

The generated chlorophyll fluorescence set is subjected to various pre-processing operations including noise removal, contrast enhancement. Pre-processed images are subjected to segmentation to increase water stress detection accuracy for automation
DOI: 10.17632/4y8s925fkm.4
title: Pre-processing of drought/water stress detection chlorophyll fluorescence wheat images for efficient segmentation

description: The data consist of a file system-based data of Raj 3765  variety of wheat. There are twenty-four chlorophyll fluorescence images  (Control and Drought) that have been captured for a period of sixty days. A total of (1440 x 2) images are used for this research work.

The generated chlorophyll fluorescence set is subjected to various pre-processing operations including noise removal, and contrast enhancement. Pre-processed images are subjected to segmentation to increase water stress detection accuracy for automation in machine learning algorithms
DOI: 10.17632/h8kpjtdgpr.1
title: Vulnerability to angling of hatchery steelhead

description: Genotypic data for natural origin winter-run steelhead (Oncorhynchus mykiss) spawned at the Alsea Hatchery in 2015 and 2016, and their putative adult offspring.

Parents (broodstock) and offspring were collected either by anglers or in-river fish traps.  Method and date of collection recorded for all steelhead.  Spawning date recorded for parents.

Statistical tests were conducted to evaluate whether the offspring of broodstock collected by anglers would be more vulnerable to angling.
Results indicated that offspring of angler-collected broodstock were not more likely to be caught by anglers, and that trap-caught broodstock produced significantly more adult offspring than angler-caught broodstock.
DOI: 10.17632/h8kpjtdgpr.2
title: Vulnerability to angling of hatchery steelhead

description: Genotypic data for natural origin winter-run steelhead (Oncorhynchus mykiss) spawned at the Alsea Hatchery in 2015 and 2016, and their putative adult offspring.

Parents (broodstock) and offspring were collected either by anglers or in-river fish traps.  Method and date of collection recorded for all steelhead.  Spawning date recorded for parents.

Statistical tests were conducted to evaluate whether the offspring of broodstock collected by anglers would be more vulnerable to angling.
Results indicated that offspring of angler-collected broodstock were more likely to be caught by anglers than trapped (significant difference in 1 of 2 years), but that trap-caught broodstock consistently produced significantly more adult offspring than angler-caught broodstock.
DOI: 10.17632/vtzdtp5j6z.1
title: Data and code for: On the Interpretation of Giving in Dictator Games When the Recipient is a Charity

description: Data generated by the experiments reported in the paper of the same name as in the title above, which has been accepted for publication in the Journal of Economic Behavior & Organization.

The results replicate the findings of List (2007) that dictators in dictator games give substantially less to anonymous recipients when options to take money from the recipient are added, but giving patterns are similar when take options are added if the recipient is a charity.

All results can be reproduced using the dataset and Stata do file that are provided. All that needs to be changed is the directory that is set that indicates where you have the dataset saved.
DOI: 10.17632/bvwc3t7m34.1
title: Activation of STAT3 in Lymphocytes associated with Central Centrifugal Cicatricial Alopecia - Supplemental materials

description: This data contains supplemental information for a publication titled "Activation of STAT3 in Lymphocytes associated with Central Centrifugal Cicatricial Alopecia "
DOI: 10.17632/krghysr87y.1
title: Dataset of Symptom Severity Score, Bristol Stool Form Scale, and number of weekly bowel movements for paediatric chronic functional constipation.

description: As part of a pilot randomized controlled trial, the demographic information such as age, sex, type of birth, and type of lactation were collected, as well as Symptom Severity Score and Bristol Stool Form Scale scores, and number of weekly bowel movements at various stages of the treatment. These data were collected over a period of years, with a 5 years difference between the first and last data collection.
DOI: 10.17632/9xpx3wt82r.1
title: Process signature for porosity-dominant fatigue scattering of materials processed by laser fusion

description: fatigue data.xlsx - Excel file of data from a fatigue test; variables: cycle count, frequency (Hz), and machine power (%) 
regression script.R - an R script to create regression lines for the different stages of the fatigue process
DOI: 10.17632/wvy9fmx3cx.1
title: openESEA user test raw data

description: To validate version 2 of the openESEA DSL, we have run a user test. This spreadsheet contains the anonymised raw data obtained as part of the user test.
DOI: 10.17632/ymnz26h6wh.1
title: Dataset EA y TIC

description: Dataset sobre estudio realizado correspondiente a Estilos de Aprendizaje y usos de TIC en estudiantes universitarios
DOI: 10.17632/vwkhgr6pvr.1
title: CmVCall

description: The sequencing datafiles of the control DNA 9947A and two synthesized sequences.
DOI: 10.17632/bbr52fxd3t.1
title: Replication Data for: Multidimensional Scale Development and Validation: University Service Quality (UNIQUAL)

description: This dataset includes replication data for the paper "Sann, R., Lai, P.-C., Liaw, S.-Y. and Chen, C.-T. (2023), "Multidimensional scale development and validation: university service quality (UNIQUAL)", Journal of Hospitality and Tourism Insights, Vol. ahead-of-print No. ahead-of-print. https://doi.org/10.1108/JHTI-08-2022-0343".
DOI: 10.17632/yyrn7g3swz.1
title: Ejercicios de comunicación  para el cambio social en Colombia, mas allá de la difusión

description: Corresponde a una ponencia presentada en  la Asociación de Facultades de Comunicación Social  AFACOM, en la que se socializaron resultados  parciales de  la investigación titulada  "Construcción epistemológica desde registro de  experiencias de la comunicación para el desarrollo , el cambio social y el buen vivir en Colombia" Dentro del contexto de un amplio proyecto para la construcción de un
Observatorio de Comunicación para el desarrollo y el cambio social que se hace necesario reconocer más allá de las teorías los postulados
conceptuales existentes, los procesos comunicativos que en términos de Desarrollo, Cambio Social y Buen vivir se escenifican en el país.  Durante los últimos años aumentaron las formas, medios y procesos de la llamada otra comunicación, comunicación alternativa, comunicación para el desarrollo, comunicación para el Cambio Social y otros varios nombres que se le aplica a estas manifestaciones.
Este aumento, que llego a registrar más de 500 formas de Comunicación tan solo en la capital colombiana, implementados principalmente desde el ejercicio empírico, muestra diversidad de posibilidades de participación e inclusión en búsqueda de objetivos relacionados con la solidaridad, la construcción de cultura de paz, la participación, pero también es escenario para que las instituciones se establezcan lineamientos políticos y sociales, o para la realización y visibilización de prácticas ancestrales. 
Por ser esta un tipo de comunicación en la que la participación, las relaciones horizontales, la deconstrucción y construcción social y otros procesos ciudadanos se manifiestan ampliamente no es pertinente encasillar en postulados las prácticas y experiencias, por el contrario se busca que con estas experiencias se consolide un postulado epistémica. La investigación evidencia procesos sociales profundos, detecta mediante la lectura de las narrativas, textos, y corpus de experiencias comunicativas construcciones que determinan el concepto diferencial de las formas, medios y procesos comunicativos enmarcados en este contexto.  Inicialmente se sistematizó  la documentación que permitió dar una mirada global al tipo de publicaciones que registran experiencias de Comunicación para el Desarrollo, el Cambio Social y el Buen Vivir. seguidamente se pudo Categorizar conceptualmente para  lograr la comprensión de los aportes que desde las experiencias ya registradas  condujeron a la  propuesta conceptual. con este insumo se consolidó un planteamiento  desde las propuestas empíricas frente a los lineamientos que se  discuten en el ámbito teórico
DOI: 10.17632/j6sw9s77rp.1
title: TsaiandWu

description: Thermal wheel