cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.6177011.v1
title: Supplementary Material for: A Rare Cause of Juvenile Stroke: Extracranial Carotid Artery Aneurysm with Venous Complete Reconstruction of the Carotid Bifurcation

description: Extracranial carotid artery aneurysms (ECAA) are a rare cause of embolic stroke. The underlying etiology is variable, with atherosclerosis being the most common entity in older subjects. Several treatments have been developed over the last 20 years, but the preferred method remains unknown. Notwithstanding the widespread use of endovascular techniques, surgical reconstruction by means of a bifurcated venous bypass graft should be applied in younger patients. In this way, it is possible to avoid major concerns about the development of long-term intrastent restenosis, and also to spare the external carotid artery which represents the main branch for the ipsilateral cerebral and facial perfusion. We propose ECAA resection and interposition of the inverted great saphenous vein to both the internal and external carotid artery by means the use of a tributary, i.e., the Giacomini vein.
DOI: 10.6084/m9.figshare.6177008
title: Dataset for: The AAA protein spastin possesses two levels of basal ATPase activity.

description: The AAA ATPase spastin is a microtubule-severing enzyme that plays important roles in various cellular events including axon regeneration. Herein, we found that the basal ATPase activity of spastin is negatively regulated by spastin concentration. By determining a spastin crystal structure, we demonstrated the necessity of inter-subunit interactions between spastin AAA domains. Neutralization of the positive charges in the microtubule-binding domain (MTBD) of spastin dramatically decreased the ATPase activity at low concentration, although the ATP-hydrolyzing potential was not affected. These results demonstrate that, in addition to the AAA domain, the MTBD region of spastin is also involved in regulating ATPase activity, making interactions between spastin protomers more complicated than expected.
DOI: 10.6084/m9.figshare.6177008.v1
title: Dataset for: The AAA protein spastin possesses two levels of basal ATPase activity.

description: The AAA ATPase spastin is a microtubule-severing enzyme that plays important roles in various cellular events including axon regeneration. Herein, we found that the basal ATPase activity of spastin is negatively regulated by spastin concentration. By determining a spastin crystal structure, we demonstrated the necessity of inter-subunit interactions between spastin AAA domains. Neutralization of the positive charges in the microtubule-binding domain (MTBD) of spastin dramatically decreased the ATPase activity at low concentration, although the ATP-hydrolyzing potential was not affected. These results demonstrate that, in addition to the AAA domain, the MTBD region of spastin is also involved in regulating ATPase activity, making interactions between spastin protomers more complicated than expected.
DOI: 10.17028/rd.lboro.6177005
title: Virtual Reality, Human Factors, and the High Street: Literature Review

description: This item contains:1. Classification sheet for 89 key journal papers relating to virtual reality and high street retail. Classification is by discipline and year of publication.2. Reference list of all papers used in the Literature Review3. Codebook
DOI: 10.17028/rd.lboro.6177005.v1
title: Virtual Reality, Human Factors, and the High Street: Literature Review

description: This item contains:1. Classification sheet for 81 key journal papers relating to virtual reality and high street retail. Classification is by discipline and year of publication.2. Reference list of all papers used in the Literature Review3. Codebook
DOI: 10.6084/m9.figshare.6177002
title: Supplementary Material for: “Kissing Nodules” in Saber-Sheath Trachea

description: Medicine
DOI: 10.6084/m9.figshare.6177002.v1
title: Supplementary Material for: “Kissing Nodules” in Saber-Sheath Trachea

description: Medicine
DOI: 10.6084/m9.figshare.6176957
title: Awareness of acute kidney injury risk factors and perspectives on its practice guidelines

description: <b>Objectives</b>: Identifying and assessing risk factors for acute kidney injury (AKI) are crucial for its early detection and possible intervention to prevent AKI and associated adverse outcomes. This study aimed to investigate AKI risk factor awareness and risk assessment by healthcare professionals and to evaluate perspectives on the Kidney Disease Improving Global Outcomes AKI guidelines. <b>Methods</b>: This cross-sectional survey-based study was conducted among healthcare professionals (physicians and pharmacists) at XXX from December 2016 to February 2017. <b>Results</b>: Among the respondents (117 physicians and 135 pharmacists), 78% were aged ≤38 years, 57% were men, and 70% had &lt;9 years of experience. Respondents varied in their knowledge of the 25 risk factors for AKI and 15 nephrotoxic drugs: 96% were aware of nephrotoxic medication, whereas 20% acknowledged female sex as an AKI risk factor, and 92% agreed with aminoglycoside, while 47% agreed with ciprofloxacin as nephrotoxic drugs. A significantly higher percentage of physicians identified individual AKI risk factors than pharmacists; however, a significantly higher percentage of pharmacists identified individual AKI-causing drugs than physicians. Although 77% of respondents encountered AKI cases in their practice, only half of them performed AKI risk assessment, and 42% stratified patients’ AKI risk according to their presenting risk factors or documented AKI in previous medical history. Seventy-one percent of respondents agreed that practice guidelines improve patient outcome, and 69% thought these guidelines help standardize care and ensure that patients are treated in consistently. <b>Conclusion</b>: While the majority of the respondents had a positive perspective toward AKI guidelines, a large variation in their knowledge of AKI risk factors, risk assessment, and nephrotoxic drugs was found. Educational efforts are needed to raise awareness and thereby reduce this variation.
DOI: 10.6084/m9.figshare.6176957.v1
title: Awareness of acute kidney injury risk factors and perspectives on its practice guidelines

description: <b>Objectives</b>: Identifying and assessing risk factors for acute kidney injury (AKI) are crucial for its early detection and possible intervention to prevent AKI and associated adverse outcomes. This study aimed to investigate AKI risk factor awareness and risk assessment by healthcare professionals and to evaluate perspectives on the Kidney Disease Improving Global Outcomes AKI guidelines. <b>Methods</b>: This cross-sectional survey-based study was conducted among healthcare professionals (physicians and pharmacists) at XXX from December 2016 to February 2017. <b>Results</b>: Among the respondents (117 physicians and 135 pharmacists), 78% were aged ≤38 years, 57% were men, and 70% had &lt;9 years of experience. Respondents varied in their knowledge of the 25 risk factors for AKI and 15 nephrotoxic drugs: 96% were aware of nephrotoxic medication, whereas 20% acknowledged female sex as an AKI risk factor, and 92% agreed with aminoglycoside, while 47% agreed with ciprofloxacin as nephrotoxic drugs. A significantly higher percentage of physicians identified individual AKI risk factors than pharmacists; however, a significantly higher percentage of pharmacists identified individual AKI-causing drugs than physicians. Although 77% of respondents encountered AKI cases in their practice, only half of them performed AKI risk assessment, and 42% stratified patients’ AKI risk according to their presenting risk factors or documented AKI in previous medical history. Seventy-one percent of respondents agreed that practice guidelines improve patient outcome, and 69% thought these guidelines help standardize care and ensure that patients are treated in consistently. <b>Conclusion</b>: While the majority of the respondents had a positive perspective toward AKI guidelines, a large variation in their knowledge of AKI risk factors, risk assessment, and nephrotoxic drugs was found. Educational efforts are needed to raise awareness and thereby reduce this variation.
DOI: 10.6084/m9.figshare.6176939
title: National culture and operations management: a structured literature review

description: National culture has received a substantial amount of interest in the operations management literature. We present the first structured review of articles studying national culture in operations management. Our search returned 51 papers published in ten leading journals between 2000 and 2017. We sort and analyse the papers according to three focus areas of operations management (<i>strategy</i>, <i>execution</i> and <i>improvement</i>). We also analyse the papers according to whether they address the <i>relevance</i> of national culture, the <i>impact</i> of national culture or the <i>actions</i> managers can use to manage or mitigate the effects of national culture. We find that national culture appears as a relevant variable in all focus areas of operations management research but that the direction and strength of its impact remain undetermined. Only a handful of papers address how managers can actively deal with challenges related to national culture. We propose a research agenda and a guiding framework for future research.
DOI: 10.6084/m9.figshare.6176939.v1
title: National culture and operations management: a structured literature review

description: National culture has received a substantial amount of interest in the operations management literature. We present the first structured review of articles studying national culture in operations management. Our search returned 51 papers published in ten leading journals between 2000 and 2017. We sort and analyse the papers according to three focus areas of operations management (<i>strategy</i>, <i>execution</i> and <i>improvement</i>). We also analyse the papers according to whether they address the <i>relevance</i> of national culture, the <i>impact</i> of national culture or the <i>actions</i> managers can use to manage or mitigate the effects of national culture. We find that national culture appears as a relevant variable in all focus areas of operations management research but that the direction and strength of its impact remain undetermined. Only a handful of papers address how managers can actively deal with challenges related to national culture. We propose a research agenda and a guiding framework for future research.
DOI: 10.6084/m9.figshare.6176927
title: Known Undisclosed Paid Editors (English Wikipedia)

description: This dataset contains a manually curated set of known undisclosed paid editor (UPE) accounts from Wikipedia. This is not a complete set of known editors. Editors who do not appear in this set are not guaranteed to not be paid editors.<br>See also https://en.wikipedia.org/wiki/Wikipedia:Paid-contribution_disclosure<br><br>The dataset contains four columns:<br> - <b>user_name</b>: The username of the UPE - <b>case_page_name</b>: The page name (title) of a page describing the case through which paid editing was discovered. - <b>type</b>: One of three types of UPEs (described below) - <b>notes</b>: Any notes that a dataset curator chose to include with the example. <br><br><br>Type 1User makes just over 10 minor edits. Is quiet for a few days well waiting for autoconfirm (user right) to kick in (takes 4 days). Then creates a promotional article in one big edit followed by the account going silent.This is the main priority. These are present in the largest numbers and are the clearest pattern. They also cause the most damage to our shared brand.Type 2User is an obvious newbie. Makes lots of mistakes. Often turns out to be internal staff. Not a key priority. We already manage these cases fairly well as they are often so obvious.Type 3Undisclosed paid editor, but one who only moves on to new accounts once their current account gets detected. A serious problem--these will be harder to detect as we will have smaller numbers of these cases. Also a long time will need to pass before a pattern becomes present
DOI: 10.6084/m9.figshare.6176795
title: Multi-disciplinary investigations at PoW Camp 198, Bridgend, S. Wales: site of a mass escape in March 1945

description: The largest escape of German Prisoner of War (PoW) in WW2 was in March 1945 from Camp 198, situated in Bridgend, South Wales, UK. Since camp closure the site has become derelict, and has not been scientifically investigated. This paper reports on the search to locate the PoW escape tunnel that was dug from Hut 9. This hut remains in remarkable condition, with numerous PoW graffiti still present. Also preserved is a prisoner-constructed false wall in a shower room behind which excavated material was hidden, though the tunnel entrance itself has been concreted over. Near-surface geophysics and ground-based LiDAR were used to locate the tunnel. Mid-frequency GPR surveys were judged optimal, with magnetometry least useful due to the above-ground metal objects. Archaeological excavations discovered the intact tunnel and bed-board shoring. With Allied PoW escape camp attempts well documented, this investigation provides valuable insight into German escape efforts.
DOI: 10.6084/m9.figshare.6176795.v1
title: Multi-disciplinary investigations at PoW Camp 198, Bridgend, S. Wales: site of a mass escape in March 1945

description: The largest escape of German Prisoner of War (PoW) in WW2 was in March 1945 from Camp 198, situated in Bridgend, South Wales, UK. Since camp closure the site has become derelict, and has not been scientifically investigated. This paper reports on the search to locate the PoW escape tunnel that was dug from Hut 9. This hut remains in remarkable condition, with numerous PoW graffiti still present. Also preserved is a prisoner-constructed false wall in a shower room behind which excavated material was hidden, though the tunnel entrance itself has been concreted over. Near-surface geophysics and ground-based LiDAR were used to locate the tunnel. Mid-frequency GPR surveys were judged optimal, with magnetometry least useful due to the above-ground metal objects. Archaeological excavations discovered the intact tunnel and bed-board shoring. With Allied PoW escape camp attempts well documented, this investigation provides valuable insight into German escape efforts.
DOI: 10.6084/m9.figshare.6176777
title: Children's Burials in Fifth-Century Britain and Connections to the Roman Past

description: This paper considers the relationship between child burials and the way burial parties used them to create connections to the Roman past during Britain's long fifth century, AD 350–550. It examines how both children and adults were buried with late-Roman and early-fifth-century material culture such as bracelets, coins, repurposed Roman curiosities and disc brooches. During the fifth century, though these items were buried with individuals of all ages, the total grave goods assemblage of which they were a part differed for children and adults. Children were usually buried only with Roman material culture, whereas adults were also given items from Anglo-Saxon or other early medieval material cultures. As the chronological distance between a community and the Roman past lengthened, the graves of children – the future of the living community – were used to commemorate or construct connections to the Roman past.
DOI: 10.6084/m9.figshare.6176777.v1
title: Children's Burials in Fifth-Century Britain and Connections to the Roman Past

description: This paper considers the relationship between child burials and the way burial parties used them to create connections to the Roman past during Britain's long fifth century, AD 350–550. It examines how both children and adults were buried with late-Roman and early-fifth-century material culture such as bracelets, coins, repurposed Roman curiosities and disc brooches. During the fifth century, though these items were buried with individuals of all ages, the total grave goods assemblage of which they were a part differed for children and adults. Children were usually buried only with Roman material culture, whereas adults were also given items from Anglo-Saxon or other early medieval material cultures. As the chronological distance between a community and the Roman past lengthened, the graves of children – the future of the living community – were used to commemorate or construct connections to the Roman past.
DOI: 10.6084/m9.figshare.6176762.v1
title: Remarks on kernel Bayes’ rule

description: The kernel Bayes’ rule has been proposed as a nonparametric kernel-based method to realize Bayesian inference in reproducing kernel Hilbert spaces. However, we demonstrate both theoretically and experimentally that the way of incorporating the prior in the kernel Bayes’ rule is unnatural. In particular, we show that under some reasonable conditions, the posterior in the kernel Bayes’ rule is completely unaffected by the prior, which seems to be irrelevant in the context of Bayesian inference. We consider that this phenomenon is in part due to the fact that the assumptions in the kernel Bayes’ rule do not hold in general.
DOI: 10.6084/m9.figshare.6176747
title: Temporary FC-SEMS for type II ERCP-related perforations: a case series from two referral centers and review of the literature<sup>*</sup>

description: <b>Background and aim:</b> Some case reports have shown that fully covered self-expandable metal stents (FC-SEMS) are effective in cases of Stapfer Type II perforation as rescue treatment. The aim of the study was to assess the efficacy and safety of temporary placement of FC-SEMS as primary treatment for Type II perforations and review the literature regarding the use of FC-SEMS in this setting. <b>Patients and method:</b> Retrospective analysis of consecutive patients with Type II perforation treated with immediate placement of FC-SEMS. Primary outcomes were need for surgery and mortality rate. Secondary outcomes were complications, technical and clinical success, time to post-operative feeding, length of the hospitalization and time to stent removal. <b>Results:</b> Overall, 18 consecutive patients were enrolled (median age 71.5). All patients were treated with FC-SEMS (6–10 mm, 4–8 cm long). In all patients, there were no need for surgery, and no patient died. Technical and clinical success were achieved both in 100% of cases. The median time to stent removal was 43 (2–105) days. The median hospital stay was of 10 (4–21) days. Median time to post-operative feeding was 4 days (2–15). <b>Conclusion:</b> FC-SEMS placement could be a safe and effective treatment in Type II perforations and represent a valuable development and innovation of conservative treatment.
DOI: 10.6084/m9.figshare.6176747.v2
title: Temporary FC-SEMS for type II ERCP-related perforations: a case series from two referral centers and review of the literature<sup>*</sup>

description: <b>Background and aim:</b> Some case reports have shown that fully covered self-expandable metal stents (FC-SEMS) are effective in cases of Stapfer Type II perforation as rescue treatment. The aim of the study was to assess the efficacy and safety of temporary placement of FC-SEMS as primary treatment for Type II perforations and review the literature regarding the use of FC-SEMS in this setting. <b>Patients and method:</b> Retrospective analysis of consecutive patients with Type II perforation treated with immediate placement of FC-SEMS. Primary outcomes were need for surgery and mortality rate. Secondary outcomes were complications, technical and clinical success, time to post-operative feeding, length of the hospitalization and time to stent removal. <b>Results:</b> Overall, 18 consecutive patients were enrolled (median age 71.5). All patients were treated with FC-SEMS (6–10 mm, 4–8 cm long). In all patients, there were no need for surgery, and no patient died. Technical and clinical success were achieved both in 100% of cases. The median time to stent removal was 43 (2–105) days. The median hospital stay was of 10 (4–21) days. Median time to post-operative feeding was 4 days (2–15). <b>Conclusion:</b> FC-SEMS placement could be a safe and effective treatment in Type II perforations and represent a valuable development and innovation of conservative treatment.
DOI: 10.6084/m9.figshare.6176747.v1
title: Temporary FC-SEMS for type II ERCP-related perforations: a case series from two referral centers and review of the literature<sup>*</sup>

description: <b>Background and aim:</b> Some case reports have shown that fully covered self-expandable metal stents (FC-SEMS) are effective in cases of Stapfer Type II perforation as rescue treatment. The aim of the study was to assess the efficacy and safety of temporary placement of FC-SEMS as primary treatment for Type II perforations and review the literature regarding the use of FC-SEMS in this setting. <b>Patients and method:</b> Retrospective analysis of consecutive patients with Type II perforation treated with immediate placement of FC-SEMS. Primary outcomes were need for surgery and mortality rate. Secondary outcomes were complications, technical and clinical success, time to post-operative feeding, length of the hospitalization and time to stent removal. <b>Results:</b> Overall, 18 consecutive patients were enrolled (median age 71.5). All patients were treated with FC-SEMS (6–10 mm, 4–8 cm long). In all patients, there were no need for surgery, and no patient died. Technical and clinical success were achieved both in 100% of cases. The median time to stent removal was 43 (2–105) days. The median hospital stay was of 10 (4–21) days. Median time to post-operative feeding was 4 days (2–15). <b>Conclusion:</b> FC-SEMS placement could be a safe and effective treatment in Type II perforations and represent a valuable development and innovation of conservative treatment.
DOI: 10.6084/m9.figshare.6176744
title: Infliximab restores colonic barrier to adherent-invasive <i>E. coli</i> in Crohn’s disease via effects on epithelial lipid rafts

description: <b>Objective:</b> Infliximab is important in the therapeutic arsenal of Crohn’s disease (CD). However, its effect on mucosal barrier function is not fully understood. Adherent-invasive <i>Escherichia coli</i> (AIEC) are important in CD pathophysiology, but the transmucosal uptake routes are partly unknown. We investigated effects of infliximab on uptake of colon-specific AIEC HM427 across CD colonic mucosa. <b>Materials and methods:</b> Endoscopic biopsies from non-inflamed colon of seven patients with CD, before and after two infliximab infusions, and eight non-inflammation controls, were mounted in Ussing chambers. Paracellular permeability (<sup>51</sup>Cr-EDTA) and transmucosal passage of GFP-expressing HM427 were studied. Mechanisms of HM427 transepithelial transport were investigated in Caco-2 monolayers treated with TNF, in the presence of infliximab and/or endocytosis inhibitors. <b>Results:</b> Before infliximab treatment, colonic passage of HM427 [CD: 2475 CFU (450–3000); controls 1163(225–1950)] and <sup>51</sup>Cr-EDTA permeability were increased in CD (<i>p</i> <b>Conclusion:</b> Infliximab restored the colonic barrier to AIEC in CD; an effect partially mediated by blocking lipid rafts in epithelial cells. This ability likely contributes to infliximab’s clinical efficacy in colonic CD.