cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.14457/cu.the.2005.1755
title: Analysis of elements released from base metal alloys used in prosthodontics

description: The objective of the research was to analyse the types and amounts of elements released from eight unpolished and polished base metal casting dental alloys used in Prosthodontics. The differences in corrosion resistance among alloys in both unpolished and polished groups were assessed. The differences in the amounts of elements released between unpolished and polished alloys were compared. Eight base metal alloys were cast into a cubic shape measuring 3x7x8 mm. There were six specimens in each group (n=6). Each specimen was ultrasonically cleaned in ethanol and non-ionized distilled water, then immersed in plastic centrifugal tube with lactic acid/NaCl solution and maintained at 37 ํC for 336 hours. The ratio of the specimen surface area to volume of solution was 0.60 cm[superscript 2]/ml. Specimens were then removed and the concentration of the elements released in the solution was analyzed using the inductive coupled plasma optical emission spectrophotometer (ICP-OES). The one-way analysis of variance (ANOVA) and the independent sample t-test method were used to analyze with 95% confidence interval ([alpha] = 0.05). The amount of elements released ranged from 15.25 to 503.42 [microgram]/cm[superscript 2] in the polished groups and from 23.22 to 2, 426.82 [microgram]/cm[superscript 2] in the unpolished groups. The elements released were not proportionate to the bulk alloys' nominal composition. There were statistically significant differences in the total elements released among eight alloys in both unpolished and polished group (p&lt;0.001) Alloys composed with a high chromium component were likely to show a higher resistance to corrosion. Polished alloys released significantly less amounts of elements than unpolished alloys (p&lt;0.05). In conclusion, the polishing procedure reduces the amount of elements released from 25% up to 90%
DOI: 10.14457/cu.the.2005.1756
title: Antioxidants from Uvaria rufa Blume roots

description: In the research for antioxidant from medicinal herbs, the 40 Thai medicinal plants were preliminary evaluated using TLC autographic assay with 2,2-Diphenyl-1-(2,4,6-trinitrophenyl)hydrazyl (DPPH) as a stable radical. The CH[subscript 2]CI[subscript 2] and butanolic extracts of Uvaria rufa roots (Pee-Puan-Noi) were found to have a promising activity. Therefore, this plant was selected for futher investigation. Chromatographic separation of these two extracts led to the isolation of fifteen known compounds. Six flavonoids, 2,5-dihydroxy-7-methoxy flavanone (1), tectochrysin (2), 5-hydroxy-7-methoxy flavanone (3), 6,7-O,O-dimethylbaicalein (6), 7-O-methylwogonine (7) and 2,5-dihydroxy-6,7-dimethoxy flavanone (8), together with two aromatic compounds, benzyl benzoate (4) and 2-methoxybenzyl benzoate (5), were isolated from the CH[subscript 2]CI[subscript 2] crude extract. While seven alkaloids, liriodenine (9), lanuginosine (10), oxoanolobine (11), roemerine (12), anonaine (13), xylopine (14) and roemeroline (15) were isolated from butanolic crude extract. All the compounds, except for 1, 2, 6 and 7, were isolated from this plant for the first time. The structures of all isolated compounds were elucidated on the basis of spectroscopic methods, as well as comparison with previously reported. The antioxidant capability was determined using three complementary in vitro assays, the DPPH radicals scavenging activity, the superoxide radicals scavenging activity and the inhibition of xanthine oxidase activity. Compound 8 showed the highest scavenging activity on DPPH and superoxide radicals with IC[subscript 50] value 0.16 and 1.03 mg/mL, respectively. In addition, the inhibitory activity against xanthine oxidase, no compounds displayed good activity as a xanthine oxidase inhibitor.
DOI: 10.14457/cu.the.2005.1757
title: Frauenfiguren als reprasentationen von burgerlicher existenz und kunstlerexistenz bei E.T.A. Hoffmann

description: In der vorliegenden Magisterarbeit warden die Frauenfiguren in sieben Werken E. T. A. Hoffmanns untersucht, namlich Don Juan, Der goldene Topf, Die Jesuiterkirche in G., Rat Krespel, Der Artushof, Die Bergwerke zu Falun und Meister Martin der Kufner und seine Gesellen. Die Arbeit mochte untersuchen, wie Hoffmann die Problematik der Kunstlerexistenz durch diese Figuren gestaltet. Wie die Frauenfiguren dargestellt und welche Funktionen ihen zugewiesen warden, wird ebenfalls untersucht. Aus der Untersuchung geht hervor, dass es zwei Typen der Frauenfiguren in Hoffmanns Werken gibt, namlich die Frauengestalten innerhalb und au berhalb der burgerlichen Welt. Die beiden vertreten zwei gegensatzliche Lebensentwurfe von Burger- und Kunstlertum. Der erste Typ ist durch zwei wichtige Merkmalen zu erkenne, namlich seine Beschaftigung als Hausfrau und die Notwendigkeit, verheiratet zu sein. Hingegen ist der zweite Typ vorwiegend durch sein Verhaltnis zu Kunst undFantasie gekennzeichnet. Die beiden Typen warden in unterschiedliche Konstellationen eingesetzr, scheinen jedoch dieselbe Funktionen zu haben, namlich die Diskrepanz der beiden Welten durch ihre Taten und Verhaltnisse zu den Helden zu thematisieren. Die Losung des Konflikts variiert in den Erzahlungen, fuhrt jedoch fast zu dem gemeinsamen Fazit, dass es undenkbar ist, die Transzendenz irdisch zu machen. ZweiErzahlungen, die eine Ausnahme bilden, leiten zu der These uber, dass es in Hoffmanns Werke eine Strukturwandlung zur Versohnung der beiden Welten geben konnte.
DOI: 10.14457/cu.the.2005.1758
title: Purification and characterization of leucine dehydrogenase from Alcaligenes faecalis

description: Leucine dehydrogenase producing bacteria were screened from soil sample and the isolate which produced the highest enzyme activity was identified as Alcaligenes faecalis. Optimum condition for L-Leucine dehydrogenase production was cultivation in 1% peptone medium pH 7.2 at 37ํC for 24 hours. After the enzyme was purified to homogeneity by DEAE-Toyopearl, Butyl-Toyopearl and Hitrap Q chromatography columns, % recovery and purification fold were 16.4 and 66.4, respectively. The enzyme had the molecular weight of 536,000 daltons and consisted of 10 identical subunits of 52,000 daltons. Substrats specificty of the enzyme on L-valine and L-isoleucine were 1.33 and 1.13 fold of that on L-leucine in oxidative deamination. In reductive amination, substrate specificity on [alpha]-ketoisovalerate, [alpha]-ketovalerate and [alpha]-keto-[beta]-methylvalerate were 2.0, 1.35 and 1.23 fold of that on [alpha]-ketoisocaprorate. The coenzyme specificity on 3-acetylepyridine adinine dinucleotide was about 4.78 fold higher than NAD[supercript +]. The optimum pH for oxidative deamination and reductive amination were 10.8 and 8.8 where as optimum temperatures were 45 ํC, and 55 ํC respectively. The enzyme retained its full activity upon the incubation at 45 ํC for 8 hours. The enzyme activity was completely inhibited by HgCI [subscript2] at final concentration of 1 mM. Chemical modification of the enzyme at tryptophan, methionine and lysine residues by incubation with 10 mM of group-specific reagents: N-bromosuccinimide, chloramine T and 2,4,6- trinitrobenzenesulfonic acid, respectively, led to completely loss of enzyme activity. The apparent K[subscript m] values for L-leucine, L-isoleuine, L-valine, NAD[superscript +], NADH, [alpha]-ketoisocaproate and ammonia were 4.2, 4.3, 14.0, 0.44, 0.02, 3.33 and 100 mM, respectively. The steady state kinetic studies including product inhibition on the enzyme reaction indicated that the oxidative deamination proceeds through a sequential ordered binary-ternary-ternary mechanism in which NAD[superscript +] binds first to the enzyme followed by L-leucine and products are released in the order of ammonia, [alpha]-ketoisocaproate and NADH, respectively. N-terminal sequence was M E I F N Y M E Q A D Y E Q L V I X Q D and internal amino acid sequence of the enzyme were, PGPXGPAGSKG (or V) EPGPAGPXG, T (or L, Y, V) LPGLAGTXG and RDNIPSYVAADRLAEERIRVA.
DOI: 10.14457/cu.the.2005.1759
title: Effect of formulation variables on adsorption of DTP-JE antigens on adjuvants

description: Aluminium hydroxide gel (AH) and aluminium phosphate gel (AP) were individually adsorbed with diphtheria toxoid (DT), tetanus toxoid (TT) or JE antigen at different conditions: temperature 37 ํC and 9 ํC; pH 6.0 to 7.4 in 0.01 M phosphate buffer and centrifuged to precipitate the adsorbed adjuvant at 3,000 rpm. The extent of adsorption of adsorbed single antigen AH suggested that DT and JE favored to adsorb at 9 ํC than 37 ํC, whereas TT preferred at 37 ํC. In addition, a gradual decrease in an adsorption of all antigens was observed as the pH was raised. For AP, poor adsorption of all antigens was noted. At 9 ํC, JE displayed a higher degree of adsorption, while DT and TT favored at physiological temperature. The calculated quantity of AH used in combined preparations were less than that of AP. Therefore, AH was chosen to adsorb at 9 ํC, pH 6.5. The surface charge in deionized water of AH and JE were positive while AP, DT and TT were negativeand PT was slightly negative or neutral charge. The antigens possibly adsorbed on AH and AP by electrostatic force and ligand exchange mechanism. The particle size of adsorbed AH and AP were larger than blank adjuvants. Morphology of AH and AP by SEM were spherical complex particle and aggregate irregular shape, respectively. Adsorbed AH could be observed by SEM, while adsorbed AP showed three-dimensional surface morphology from AFM. The principle peak of IR spectra and X-ray diffraction bands of adsorbed AH and AP indicated that the adsorption had no effect on their chemical structures. The antigen contents combined preparations after storage at 2-8 ํC for 3 months and analyzed by ELISA showed more DT, TT and JE content from formulation of separate adsorption than that of competitive method. Mixing time affected the antigen content of DT, TT and JE whereas adsorption process and mixing time did not affect PT content.
DOI: 10.14457/cu.the.2005.1760
title: Cloning and characterization of chitinase gene from hepatopancreas from black tiger shrimp Penaeus monodon

description: Chitinase (E.C. 3.2.1.14) is an enzyme that catalyzes the degradation of chitin. Chitinase is useful enzyme fo wide applications in several industries. A computer program was used for searching the chitinase gene in the black tiger shrimp (Penaeus monodon) database (http://pmonodon.biotec.or.th). A total of 10,100 clones were searched for chitinase gene. Three clones, two clones from a hemocyte library and another clone from hepatopancreas library, were identified as a putative chitinase gene and reconfirmed by BLASTN program. The chitinase gene, ChiHP74, found in hepatopancreas cDNA library of black tiger shrimp P. monodon has been cloned. The ChiHP74 contains an open reading frame of 1995 bp. The cDNA encoded for a polypeptide chain of 665 amino acid residues with a predicted molecular weight of 74 kDa. Sequence analysis of the deduced amino acid sequence of chitinase comprised a family 18 catalytic domain (CatD), a tachycitin like domain, and two proline rich domains at the C-terminus. In an expression of this gene, bacterial expression system and yeast expression system were used to express ChiHP74. The result showed this chitinase could not be expressed by both systems. Because of no expression of full-length fragment, CatD was chosen to clone and express instead. It was successfully expressed by using PET-17b in E. coli strain BL21 (DE3) called Chi-CatD which showed an optimum pH in two ranges of 4 and 7. The optimum temperature of this enzyme was 60degrees Celsius. Chi-CatD hydrolyzed B-chitin the best and only dimmer [(GlcNAc)2] was detected.
DOI: 10.6084/m9.figshare.12951347
title: Metadata record for: VOLCORE, a global database of visible tephra layers sampled by ocean drilling

description: This dataset contains key characteristics about the data described in the Data Descriptor VOLCORE, a global database of visible tephra layers sampled by ocean drilling. <br> Contents: <br> 1. human readable metadata summary table in CSV format 2. machine readable metadata file in JSON format
DOI: 10.6084/m9.figshare.12951347.v1
title: Metadata record for: VOLCORE, a global database of visible tephra layers sampled by ocean drilling

description: This dataset contains key characteristics about the data described in the Data Descriptor VOLCORE, a global database of visible tephra layers sampled by ocean drilling. <br> Contents: <br> 1. human readable metadata summary table in CSV format 2. machine readable metadata file in JSON format
DOI: 10.14457/cu.the.2005.1761
title: Predictors of Thai pharmacist in accessing continuing pharmaceutical education

description: Thai Pharmacy council has established a policy encouraging Thai pharmacists to carry out their continuing pharmaceutical education (CPE) through participating in academic conference, reading articles from journals, or website since 2001. Pharmacists are expected to accomplish for minimum of 10 credits granted in each year and 100 credits within five years. Therefore, this study was conducted to determine the predictable factors of accessing CPE. These factors were based on Theory of Planned Behavior (TPB) including attitude and subjective norms toward accessing CPE, and perception of barriers affecting their participations in CPE. Survey research using mailing-questionnaire was used and data on CPE score were collected from Center of continuing pharmaceutical education (CCPE). The response rate was 42.0 % (n=269). Bivariate analysis was used to explore the association of predictors and CPE score and Multiple Regression Analysis was conducted to establish the explanatory model on CPE. The result showed that the established model based on the TPB has correlation coefficient 0.21 that could explain their participation on CPE about 21 %. The significant predictors in the model were gender (p=0.02), working places of pharmacists in the Central region (p=0.03), being a member of Hospital Pharmacy Association (p=0.01), being a member of Community Pharmacy Association (p=0.00), CPE provider (p=0.01), and perception on patient influencing CPE participation (p=0.05). It was also found that academic conference was the most important channel that pharmacist chose for their participation and they required topic of CPE to be related with their practice area. The results of this study could be used to develop the appropriate strategies to promote and motivate Thai pharmacists to have more participation in CPE to achieve the Thai Pharmacy council policy and the CPE could consequently be an acceptable regulation.
DOI: 10.14457/cu.the.2005.1762
title: Application of global positioning systems (GPS) data for atmospheric water vapour variation in Thailand

description: The purpose of this research is to identify the period of southwest monsoon season in Thailand by using IWV value obtained from GPS together with other meteorological data. In addition, the obtained IWV value are used to study the effect of high pressure area and the transfer of confluence wind in the winter and summer season. A new application of GPS in Thailand is the GPS-Meteorology. GPS signal propagation delayed by atmospheric water vapour is conversed into the term of zenith wet delay (ZWD), the retrieved ZWD can be transformed to the integrated water vapour (IWV) over that GPS receiver by using Bernese GPS software version 4.2 (B-GPS_IWV). The accuracy of B-GPS_IWV can be measured by the difference between B-GPS_IWV value and the IWV obtained from the Water vapour Microwave Radiometer (MWR_IWV). The result shows that the difference is 1.34 mm and its correlation coefficient is 0.81. The southwest monsoon period can be identified by the relationship of B-GPS_IWV, wind direction change, and rainfall where the onset and withdrawal are represented by the increase and decrease of B-GPS_IWV, respectively. In addition, the passage of high pressure area can be explained by decreasing of B-GPS_IWV in 3-5 days before the high pressure area move down. Moreover, it is found that the occurrent spike of B-GPS_IWV in the day of the dominative confluence wind can be used to explain the transfer of moist air into the land.
DOI: 10.14457/cu.the.2005.1763
title: A Randomized, controlled trial to compare the effectiveness of nortriptyline plus brief motivation counseling and motivation counseling alone for smoking cessation in Thai active smokers

description: Objective: To determine the smoking abstinence rate at 3 months in Thai active smokers who use nortriptyline combined with brief motivational counseling or brief motivational counseling alone for smoking cessation. Design: Double blind randomized controlled trial. Setting: smoking cessation clinic, Faculty of Medicine, Chulalongkorn University. Method: Active smoking (more than 10 cigarettes per day) who was older than 18 years and are willing to quit smoking were randomized into control group and treatment group. Control group received brief motivation counseling and placebo. Treatment group received nortriptyling 50 mg/day and brief intervention counseling. Patients were followed up for 3 months. Success rate of smoking cessation and other secondary outcomes at 3 months were evaluated. Result: There were 68 patients in control group and 69 patients in treatment group. There were no statistically significant difference in baseline demographic data and smoking history in 2 groups. Smoking cessation rate at 3 month rate was higher in treatment group than in control group 43.5% vs 26.5% respectively, p = 0.014, OR = 2.5 95% CI 1.19-5.25). Patients received nortriptyline experienced more side effect of dry mouth than in control group. Conclusion: Nortriptyline and brief motivational counseling was more effective in smoking cessation treatment than brief motivational counseling alone at 3 months after treatment and related with minor side effects from treatment.
DOI: 10.14457/cu.the.2005.1764
title: Use case retrieval using terms and use case structure similarity computation

description: Software reuse is a key component of software engineering methodology as it helps software developers to reduce cost of software development process. At present, the software industry is highly competitive among organizations. Therefore, software developers have to find ways to reduce cost of software production as much as they can. Software reuse in a part of software requirements specification collected in a form of use case description can reduce much redundant works. Thus, this leads to the reduction of cost and time of software production. The objective of this thesis is to analyzed and design an approach for retrieving use case considering similarity of terms and structure of use cases. Information storage and retrieval theories such as automatic indexing, term weighting system, document similarity computation, and retrieval evaluation are applied in this approach. As a result, this research develops a tool to test the proposed approach. The experiment is also designed to compare this proposed approach to the existing approach which considers only terms similarity. The 3 metrics named recall, precision, and harmonic mean of information storage and retrieval theory are used to evaluate use case retrieval results. The results of this experiment indicate that this proposed approach is more effective than the existing approach.
DOI: 10.14457/cu.the.2005.1765
title: Nonlinear analysis of steel roof frames under fire

description: The current study investigates the fire resistance of the steel roof structure for a typical warehouse using the performance-based approach. Various fire scenarios are simulated using the Fire Dynamics Simulator (FDS) program. The simulation considers the location of the ignition source, the fuel type and the clearance height of the warehouse as the varying parameters. For each of the modeled fire scenarios, the behavior of the roof structure is examined using nonlinear structural analysis, taking into account the varying properties of steel under fire, with and without fire protection. Based on the fire modeling results, it is found that the fuel types significantly affect the behavior of the modeled fire in terms of the fire growth and the spread of flames. The plastic storage contents result in a rapid fire growth due to the significant feedback of heat from the flames. The wood storage contents result in a considerably slower fire growth that occurs through direct radiation from the flames to nearby objects. It is observed that the failure of the roof structure is due to three key factors: the increasing axial compression; the significant drop of the mechanical properties of steel; and the P-[Delta] effects. For the cases of plastic storage contents, the time to failure is in the range of 1100-1500 seconds and 330-400 seconds for the roof structure with and without fire protection, respectively. For the cases of the wood storage contents, the minimum time to failure is 1750 seconds for the roof structure without fire protection and the maximum time to failure is longer than 7200 seconds (the maximum burning time) when the roof structure is fire-protected. The outcome of the current study can be used to assess the safe egress time for the structure under consideration, to establish a guideline for proper design of the fire protection systems, as well as to set an initial step towards the fire risk assessment of similar structures in accordance with the national fire safety regulations.
DOI: 10.14457/cu.the.2005.1766
title: Rheology and suspending properties of modified tapioca starches

description: Five modified tapioca starches, sodium carboxymethyl tapioca starch (SCMS), cross-linked sodium carboxymethyl tapioca starch (CSCMS), pregelatinized tapioca starch (PGTS), hydroxypropyl tapioca starch (HPTS) and cross-linked hydroxypropyl tapioca starch (CHPTS) were investigated for their properties as suspending agent comparing with commercial suspending agent such as Ultrasperse®2000 (UT), xanthan gum (XG) and tragacanth (TG). SCMS with DS of 0.11, 0.22 and 0.37 were prepared by Filbert’s method and CSCMS with % phosphate content of 0.17, 0.23 and 0.32 were obtained from Kerr and Cleveland’s method. Those materials were studied for their viscosity and rheological behavior. The pseudoplastic flow was observed in all suspending agents. The effect of ionic strength, pH and type of buffer (phosphate and citrate buffer) on the viscosity and rheological behavior of those materials was evaluated. CSCMS was excluded from the study because it was very sensitive to ionic strength, buffer and pH. SCMS, PGTS, HPTS, CHPTS, UT, XG and TG at three level concentrations were used as suspending agents in ibuprofen formulation. Their physical appearance, pH, viscosity, sedimentation volume and redispersibility were evaluated to find the proper concentration of those suspending agents after keeping in room temperature for 1 month. The ibuprofen preparations containing 3 % w/v SCMS, 4 % w/v PGTS, 6 % w/v HPTS, 3 and 4 % w/v CHPTS provided the preferable suspension comparing with 4 % w/v UT, 0.4 and 0.6 % w/v XG and 1 % and 1.5 % w/v TG. The evaluation parameters including physical appearance, sedimentation volume, pH, viscosity, rheological behavior, redispersibility and % drug content were investigated during storage at room temperature and heating-cooling condition. All preparations provided the acceptable chemical stability after standing 3 months at room temperature and 8 cycles of heating-cooling condition. SCMS, PGTS and HPTS were not suitable as suspending agent because they obviously decreased the viscosity after storage. Moreover, the difficult redispersibility of compact sediment was occurred in their preparations. CHPTS was a promising suspending agent in the preparation due to its good physical appearance, redispersibility, no caking, suitable rheological behavior and comparable to those of UT, XG and TG. CHPTS was a good modified starch candidate for the development as suspending agent in the pharmaceutical industry.