cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.25625/2homi3/q3exvc
title: cmap_rainbow_bgyrm.m

description: :unav
DOI: 10.25625/2homi3/gkjjup
title: ghostscript.m

description: :unav
DOI: 10.35078/nduhyf/vmxrzs
title: Tira Barro - Faz - B.jpg

description: :unav
DOI: 10.25625/2homi3/npxhxk
title: GaussFMaxMin2D.m

description: :unav
DOI: 10.25625/2homi3/yzf9yr
title: convertTrajectories.m

description: :unav
DOI: 10.35078/nduhyf/banhil
title: Saco Grande - F - B.jpg

description: :unav
DOI: 10.25625/2homi3/6pygj5
title: gaussmodel2dwxy.m

description: :unav
DOI: 10.25625/2homi3/di8etq
title: RCC.m

description: :unav
DOI: 10.35078/nduhyf/bdt1wr
title: Santa Maria - Pov - C.jpg

description: :unav
DOI: 10.25625/2homi3/dmadwy
title: mx_psfFit_Image.mexa64

description: :unav
DOI: 10.35078/nduhyf/lmwqjx
title: Gameleira - Fz - A.jpg

description: :unav
DOI: 10.25625/2homi3/byt16a
title: loadImportPlugins.m

description: :unav
DOI: 10.35078/nduhyf/tkusby
title: Bonsucesso - FAZ - A.jpg

description: :unav
DOI: 10.25625/2homi3/i3n4g1
title: packageGUI.fig

description: :unav
DOI: 10.35078/nduhyf/bwbsxp
title: Várzea Redonda - P - A.jpg

description: :unav
DOI: 10.25625/2homi3/g1xbod
title: PatternGenerateSimple_SEP.m

description: :unav
DOI: 10.25625/2homi3/msn0cz
title: plusTipGetSubtrackCoords.m

description: :unav
DOI: 10.25625/2homi3/tvopr9
title: getGaussianPSFsigma.m

description: :unav
DOI: 10.35078/nduhyf/fl8l4t
title: Ribeirão do São Francisco - C.jpg

description: :unav
DOI: 10.25625/2homi3/6oqioe
title: RotateEMField.m

description: :unav
DOI: 10.25625/2homi3/uqh4y1
title: readIXMHTDFileM.m

description: :unav
DOI: 10.35078/nduhyf/pkmvtx
title: Buritis - Faz - J.jpg

description: :unav
DOI: 10.25625/2homi3/ichytv
title: msgboxGUI.fig

description: :unav
DOI: 10.35078/nduhyf/o6unrg
title: Porto Faria - Fz - A.jpg

description: :unav
DOI: 10.25625/2homi3/lumgox
title: PatternGeneratePos_SEP.m

description: :unav
DOI: 10.35078/nduhyf/yujjlr
title: Salto - Faz - B.jpg

description: :unav
DOI: 10.25625/2homi3/q3xrxu
title: fitGaussianMixture2D.mexmaci64

description: :unav
DOI: 10.25625/2homi3/gc6vlm
title: movieSelectorGUI.fig

description: :unav
DOI: 10.25625/2homi3/qeotrx
title: plusTipRemBegEnd.m

description: :unav
DOI: 10.35078/nduhyf/232af6
title: Lavadinho - Faz - C.jpg

description: :unav
DOI: 10.25625/2homi3/csxyhi
title: findOverlapPSFs2D.m

description: :unav
DOI: 10.35078/nduhyf/2s0k8s
title: João Martins - Pv - D.jpg

description: :unav
DOI: 10.25625/2homi3/z503rh
title: fitGaussian2D.mexmaci64

description: :unav
DOI: 10.25625/2homi3/iw1soz
title: MaskIntersectionProcess.m

description: :unav
DOI: 10.25625/2homi3/cllu5x
title: kalmanReverseLinearMotion.m

description: :unav
DOI: 10.25625/2homi3/yboila
title: gaussmlev2_matlab.m

description: :unav
DOI: 10.35078/nduhyf/d80pfm
title: Marimbondo - Faz- A.jpg

description: :unav
DOI: 10.25625/2homi3/kvdyjz
title: .gitignore

description: :unav
DOI: 10.35078/nduhyf/g3rgev
title: Capão do Ribeirão - F - B.jpg

description: :unav
DOI: 10.25625/2homi3/rjbpqt
title: plugin_fitLT_spectralSplit.m

description: :unav
DOI: 10.35078/nduhyf/e17ill
title: Várzea Redonda - Faz - A.jpg

description: :unav
DOI: 10.25625/2homi3/5uq3pc
title: TNTscalebar.m

description: :unav
DOI: 10.17863/cam.82797
title: Research data supporting "Dual-Template Approach to Hierarchically Porous Polymer Membranes"

description: ‘Fig 3’ contains images (optical and SEM) of control membranes using only F127 as an additive as well as PABA containing images. ‘Fig 4’ contains images (optical and SEM) of membranes prior to and after PABA removal. ‘Fig 5’ contains the text file ‘beer-lambert’. This file shows the maximum absorbance and concentration used to create the beer-lambert plot. This folder also contains UV Vis absorption data of eluent ethanol that samples were stored in. Samples 162 contained PABA. Samples 164 did not contain PABA. txt files give data in the form wavelength (nm), absorption. ‘Conc_calc.txt' includes the calculation performed to determine concentration of the eluent. ‘Fig 6’ contains contact angle data for control, PABA-containing, and PABA-removed membranes in the form of csv files of samples used for analysis in the form absolute time (s), relative time (s), frame number, contact angle (degrees) as the first 4 columns. ‘d’ suffix denotes the dull side of the sample. ‘s’ suffix denotes the shiny side of the sample. JPEG images of the samples are also included. ‘Permeability’ contains the data from flow-rate experiments and pore size measurements in a text file. Data listed are given as follows: Sample Name, Permeability Experiment Run 1 (mlmin-1), Permeability Experiment Run 2 (mlmin-1), Permeability Experiment Run 3 (mlmin-1), Average flow rate from permeability experiments (mlmin-1), Error in average (mlmin-1), Sample thickness (μm), Test Area (mm2), Permeability (m-2), Permeability Error (m-2), Flow rate (l/m2h), Flow rate Error (l/m2h), Pore sizes (nm) 1-50, Pore size average (nm), Pore size average error (nm)
DOI: 10.25625/2homi3/1yeaes
title: naFromLensID.m

description: :unav
DOI: 10.35078/nduhyf/mv5zgk
title: Lavradinho II - Faz - C.jpg

description: :unav
DOI: 10.25625/2homi3/xsci7q
title: cometPostTrackingProcessGUI.fig

description: :unav
DOI: 10.35078/nduhyf/exeou4
title: Ribeirão do São Francisco - B.jpg

description: :unav
DOI: 10.25625/2homi3/5irljn
title: channelGUI.fig

description: :unav
DOI: 10.25625/2homi3/jrfgxl
title: GaussianFit.m

description: :unav
DOI: 10.35078/nduhyf/jdcgwk
title: Saco Grande - Faz - C.jpg

description: :unav
DOI: 10.25625/2homi3/t3gqoz
title: pointSourceDetectionProcessGUI.m

description: :unav
DOI: 10.25625/2homi3/wmvxk8
title: verifyOutParamDescription.m

description: :unav
DOI: 10.35078/nduhyf/gyfipr
title: Buriti Grande - Faz - B.jpg

description: :unav
DOI: 10.25625/2homi3/23pezc
title: thresholdRosin.m

description: :unav
DOI: 10.35078/nduhyf/xgzcow
title: Batalha - F - B.jpg

description: :unav
DOI: 10.25625/2homi3/sxb7rz
title: ITFUNC_EXC_PATT_VIS_SEP.m

description: :unav
DOI: 10.25625/2homi3/eh2aq1
title: vectorialPSF.mexw64

description: :unav
DOI: 10.35078/nduhyf/qpgsqu
title: Rio de Janeiro - Fz - C.jpg

description: :unav
DOI: 10.25625/2homi3/9kwbll
title: DCC.m

description: :unav
DOI: 10.25625/2homi3/8lx0fv
title: getTrackSEL.m

description: :unav
DOI: 10.35078/nduhyf/8qylws
title: Barreiro Fundo - F - A.jpg

description: :unav
DOI: 10.25625/2homi3/a24dkx
title: omeroImport.m

description: :unav
DOI: 10.25625/2homi3/rttaa2
title: plotTracksDiffAnalysis2D.m

description: :unav
DOI: 10.35078/nduhyf/o3e9uj
title: Batalha - Fz - A.jpg

description: :unav
DOI: 10.25625/2homi3/edes1a
title: RadialPatternPos_SEP.m

description: :unav
DOI: 10.25625/2homi3/mkm0oy
title: cropMovie.m

description: :unav
DOI: 10.35078/nduhyf/wweypb
title: Lavadinho - Faz - D.jpg

description: :unav
DOI: 10.25625/2homi3/6dtrxp
title: imDir.m

description: :unav
DOI: 10.25625/2homi3/ufhakt
title: U2OS_alpha-tub_af647_sample1_10Au_5SiO2_50mM_MEA_pbs_power6_OD0p6_40-1.ptu

description: :unav
DOI: 10.35078/nduhyf/urcfks
title: Buritis - Faz - C.jpg

description: :unav
DOI: 10.25625/2homi3/gmm8jd
title: plugin_Gauss2DCirc.m

description: :unav
DOI: 10.25625/2homi3/lzbuif
title: conjugateGradient.m

description: :unav
DOI: 10.35078/nduhyf/lojufv
title: Buritis - Faz - G.jpg

description: :unav
DOI: 10.25625/2homi3/lgyy2v
title: read_photons.m

description: :unav
DOI: 10.35078/nduhyf/hpcj3d
title: Gama - Faz - H.jpg

description: :unav
DOI: 10.25625/2homi3/cm1l4x
title: plugin_fitLT.m

description: :unav
DOI: 10.25625/2homi3/emrfq7
title: matpush.m

description: :unav
DOI: 10.6084/m9.figshare.28783331
title: <b>Chromosome-level genome assembly and annotation of the </b><b><i>Triplophysa pappenheimi</i></b>

description: The genome annotations (.gff3), predicted coding sequences (.cds), protein sequences (.pep),and chromosome-level genome sequence files (.fa) of the <i>Triplophysa pappenheimi</i> genome assembly.
DOI: 10.15468/dl.kcyf7a
title: Occurrence Download

description: A dataset containing 36 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Atriplex madariagae Phil."
 ]
}

 The dataset includes 36 records from 13 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0021224-250402121839773/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.11321099.v1
title: MOESM2 of Understanding cause of stillbirth: a prospective observational multi-country study from sub-Saharan Africa

description: Additional file 2: Dataset S1. Cause of Death Agreement Rates
DOI: 10.6084/m9.figshare.11321051
title: MOESM7 of EGFR mutation: novel prognostic factor associated with immune infiltration in lower-grade glioma; an exploratory study

description: Additional file 7: Figure S2. Cytokine Profiling heat maps. Chemokines, lymphokines and phenotype markers of macrophages estimations of EGFR-MUT and EGFR-WT cases were revealed using heat maps.
DOI: 10.6084/m9.figshare.11321051.v1
title: MOESM7 of EGFR mutation: novel prognostic factor associated with immune infiltration in lower-grade glioma; an exploratory study

description: Additional file 7: Figure S2. Cytokine Profiling heat maps. Chemokines, lymphokines and phenotype markers of macrophages estimations of EGFR-MUT and EGFR-WT cases were revealed using heat maps.
DOI: 10.6084/m9.figshare.11321033
title: MOESM4 of EGFR mutation: novel prognostic factor associated with immune infiltration in lower-grade glioma; an exploratory study

description: Additional file 4: Table S4. PPI hub genes. The identified hub genes and the outputs of Log-rank tests. (CSV 166 kb)
DOI: 10.6084/m9.figshare.11321036
title: MOESM6 of Combination of mTORC1/2 inhibitor vistusertib plus fulvestrant in vitro and in vivo targets oestrogen receptor-positive endocrine-resistant breast cancer

description: Additional file 6: File S1. Ingenuity pathway analysis of the HBCx34 OvaR PDX models at the end of the study.
DOI: 10.6084/m9.figshare.11321039
title: MOESM5 of EGFR mutation: novel prognostic factor associated with immune infiltration in lower-grade glioma; an exploratory study

description: Additional file 5: Table S5. The COX model. The original parameters and output of COX model established by SPSS version 19. (CSV 2 kb)
DOI: 10.6084/m9.figshare.11321033.v1
title: MOESM4 of EGFR mutation: novel prognostic factor associated with immune infiltration in lower-grade glioma; an exploratory study

description: Additional file 4: Table S4. PPI hub genes. The identified hub genes and the outputs of Log-rank tests. (CSV 166 kb)
DOI: 10.6084/m9.figshare.11321036.v1
title: MOESM6 of Combination of mTORC1/2 inhibitor vistusertib plus fulvestrant in vitro and in vivo targets oestrogen receptor-positive endocrine-resistant breast cancer

description: Additional file 6: File S1. Ingenuity pathway analysis of the HBCx34 OvaR PDX models at the end of the study.
DOI: 10.6084/m9.figshare.11321039.v1
title: MOESM5 of EGFR mutation: novel prognostic factor associated with immune infiltration in lower-grade glioma; an exploratory study

description: Additional file 5: Table S5. The COX model. The original parameters and output of COX model established by SPSS version 19. (CSV 2 kb)
DOI: 10.6084/m9.figshare.11321024
title: MOESM3 of EGFR mutation: novel prognostic factor associated with immune infiltration in lower-grade glioma; an exploratory study

description: Additional file 3: Table S3. GO results. The results of Gene Ontology terms. (CSV 23 kb)
DOI: 10.6084/m9.figshare.11321015
title: MOESM2 of EGFR mutation: novel prognostic factor associated with immune infiltration in lower-grade glioma; an exploratory study

description: Additional file 2: Table S2. Limma analysis of DEGs. The outcomes of analysis of identifying differential expressed genes using Limma package of R. (CSV 195 kb)
DOI: 10.6084/m9.figshare.11321015.v1
title: MOESM2 of EGFR mutation: novel prognostic factor associated with immune infiltration in lower-grade glioma; an exploratory study

description: Additional file 2: Table S2. Limma analysis of DEGs. The outcomes of analysis of identifying differential expressed genes using Limma package of R. (CSV 195 kb)
DOI: 10.6084/m9.figshare.11321024.v1
title: MOESM3 of EGFR mutation: novel prognostic factor associated with immune infiltration in lower-grade glioma; an exploratory study

description: Additional file 3: Table S3. GO results. The results of Gene Ontology terms. (CSV 23 kb)
DOI: 10.6084/m9.figshare.11321003
title: MOESM4 of Genomic diversity and meiotic recombination among isolates of the biotech yeast Komagataella phaffii (Pichia pastoris)

description: Additional file 4. Nucleotide sequence of the ARG4del plasmid used to delete ARG4 in strain Pp4.
DOI: 10.6084/m9.figshare.11321012
title: MOESM1 of EGFR mutation: novel prognostic factor associated with immune infiltration in lower-grade glioma; an exploratory study

description: Additional file 1: Table S1. VEP prediction. The Variant Effect Predictor (VEP) outcomes of predictions on biological significance of EGFR variants. (CSV 70 kb)
DOI: 10.6084/m9.figshare.11320997
title: MOESM3 of Genomic diversity and meiotic recombination among isolates of the biotech yeast Komagataella phaffii (Pichia pastoris)

description: Additional file 3. Segregation profiles of all K. phaffii tetrads and trios analyzed, as in Fig.Â 4.
DOI: 10.6084/m9.figshare.11321003.v1
title: MOESM4 of Genomic diversity and meiotic recombination among isolates of the biotech yeast Komagataella phaffii (Pichia pastoris)

description: Additional file 4. Nucleotide sequence of the ARG4del plasmid used to delete ARG4 in strain Pp4.
DOI: 10.6084/m9.figshare.11321012.v1
title: MOESM1 of EGFR mutation: novel prognostic factor associated with immune infiltration in lower-grade glioma; an exploratory study

description: Additional file 1: Table S1. VEP prediction. The Variant Effect Predictor (VEP) outcomes of predictions on biological significance of EGFR variants. (CSV 70 kb)
DOI: 10.6084/m9.figshare.11320997.v1
title: MOESM3 of Genomic diversity and meiotic recombination among isolates of the biotech yeast Komagataella phaffii (Pichia pastoris)

description: Additional file 3. Segregation profiles of all K. phaffii tetrads and trios analyzed, as in Fig.Â 4.
DOI: 10.6084/m9.figshare.11320991
title: MOESM2 of Genomic diversity and meiotic recombination among isolates of the biotech yeast Komagataella phaffii (Pichia pastoris)

description: Additional file 2. Genotype calls at SNP sites in each ascus. Values of “0″ indicate the same nucleotide as in GS115, and “1” indicates a match to Pp4. Spores were designated as types a (his4 arg4), b (HIS4 ARG4), c (his4 ARG4) or d (HIS4 arg4). All four types of spore were recovered from tetrads; Trios 10, 22 and 19 lack a spore of type a, and Trios 31, 34 and 12 lack a spore of type d. Chromosome coordinates are from the CBS7435 reference genome assembly of Sturmberger et al. [20], NCBI accession numbers LT962476.1 to LT962479.1.
DOI: 10.6084/m9.figshare.11320991.v1
title: MOESM2 of Genomic diversity and meiotic recombination among isolates of the biotech yeast Komagataella phaffii (Pichia pastoris)

description: Additional file 2. Genotype calls at SNP sites in each ascus. Values of “0″ indicate the same nucleotide as in GS115, and “1” indicates a match to Pp4. Spores were designated as types a (his4 arg4), b (HIS4 ARG4), c (his4 ARG4) or d (HIS4 arg4). All four types of spore were recovered from tetrads; Trios 10, 22 and 19 lack a spore of type a, and Trios 31, 34 and 12 lack a spore of type d. Chromosome coordinates are from the CBS7435 reference genome assembly of Sturmberger et al. [20], NCBI accession numbers LT962476.1 to LT962479.1.
DOI: 10.6084/m9.figshare.11320946
title: MOESM1 of Epigenome-wide base-resolution profiling of DNA methylation in chorionic villi of fetuses with Down syndrome by methyl-capture sequencing

description: Additional file 1: Table S1. Clinical characteristics. Table S2. MC-seq performance of each sample. Table S3. CpG sites of each sample covered by MC-seq. Table S4. Methylation levels of DMCs in the functional genomic regions. Table S5. Methylation levels of DMCs in the fetal normal and DS brain. Table S6. Genes with DMRs. Table S7. Functional region and chromosomal location of genes with DMRs. Table S8. Primer sequences and PCR condition for methylation specific quantitative real-time PCR .
DOI: 10.6084/m9.figshare.11320505
title: RNA-seq transcriptome of Pseudomonas putida KT2440 fed with glucose as sole carbon source

description: Known for its biotechnological potential particularly in mediating environmental bioremediation, <i>Pseudomonas putida</i> KT2440 is a well-studied bacterium with varied habitats. With a genome encoding a versatile metabolism, the Gram-negative <i>P. putida</i> KT2440 can theoretically subsist on different carbon sources and remain efficient in performing desired biotechnological tasks. But, growth on different carbon sources would theoretically lead to different gene expression patterns that might ultimately impact on downstream metabolic activities and biotransformation tasks such as those required in environmental bioremediation. Hence, using a RNA-seq transcriptome of <i>P. putida </i>KT2440 subsisting on glucose as sole carbon source (ArrayExpress accession number: E-GEOD-46491), this work sought to reveal the differential gene expression pattern elicited by this preferred carbon source. After processing 0.7 million reads using an in-house MATLAB algorithm, the RNA-seq data reveals non-ribosomal peptide synthesis as major cellular processes in operation. In particular, the most highly expressed genes are <i>pvdL, fliC, pvdD, pvdJ, groL, fpvA, pvdI, fusA, </i>and <i>pvdH</i>, which was a surprise given that non-ribosomal peptide synthesis genes dominated the list of most highly expressed genes in cells at mid-exponential phase. More importantly, there was a paucity of genes inducible by glucose that top the list of most highly expressed genes, thereby, suggesting that enzymes mediating glucose catabolism are highly efficient molecular machines that do not need high expression level to afford high enzymatic activity. In summary, the presented RNA-seq transcriptome of <i>P. putida</i> KT2440 subsisting on glucose as sole carbon source might be useful in the search for differentially expressed genes when the same microbe subsists on different carbon sources such as fructose and glycerol.<br><br>
DOI: 10.6084/m9.figshare.11320517
title: empty

description: empty
DOI: 10.6084/m9.figshare.11320490
title: Supporting Information-Text EHS garnet amphibolite.pdf

description: Tables S1 to S3 are minerals chemical compositions analyzed using a JEOL JXA 8900 electron microprobe (EPM) with a 15 kV accelerating voltage, 20 nA beam current, 5 μm spot diameter, and count time of 10 s for peak and background, at the Institute of Geology, Chinese Academy of Geological Sciences. Tables S4 is zircon U–Pb dating and trace element data simultaneously conducted by laser ablation inductively coupled plasma mass spectrometry (LA–ICP–MS) at the State Key Laboratory of Geological Processes and Mineral Resources, China University of Geosciences (Wuhan). Detailed operating conditions for the laser ablation system and the ICP–MS instrument are described by Hu et al<i>.</i> (2011) and Liu et al<i>.</i> (2010).
DOI: 10.6084/m9.figshare.11320505.v1
title: RNA-seq transcriptome of Pseudomonas putida KT2440 fed with glucose as sole carbon source

description: Known for its biotechnological potential particularly in mediating environmental bioremediation, <i>Pseudomonas putida</i> KT2440 is a well-studied bacterium with varied habitats. With a genome encoding a versatile metabolism, the Gram-negative <i>P. putida</i> KT2440 can theoretically subsist on different carbon sources and remain efficient in performing desired biotechnological tasks. But, growth on different carbon sources would theoretically lead to different gene expression patterns that might ultimately impact on downstream metabolic activities and biotransformation tasks such as those required in environmental bioremediation. Hence, using a RNA-seq transcriptome of <i>P. putida </i>KT2440 subsisting on glucose as sole carbon source (ArrayExpress accession number: E-GEOD-46491), this work sought to reveal the differential gene expression pattern elicited by this preferred carbon source. After processing 0.7 million reads using an in-house MATLAB algorithm, the RNA-seq data reveals non-ribosomal peptide synthesis as major cellular processes in operation. In particular, the most highly expressed genes are <i>pvdL, fliC, pvdD, pvdJ, groL, fpvA, pvdI, fusA, </i>and <i>pvdH</i>, which was a surprise given that non-ribosomal peptide synthesis genes dominated the list of most highly expressed genes in cells at mid-exponential phase. More importantly, there was a paucity of genes inducible by glucose that top the list of most highly expressed genes, thereby, suggesting that enzymes mediating glucose catabolism are highly efficient molecular machines that do not need high expression level to afford high enzymatic activity. In summary, the presented RNA-seq transcriptome of <i>P. putida</i> KT2440 subsisting on glucose as sole carbon source might be useful in the search for differentially expressed genes when the same microbe subsists on different carbon sources such as fructose and glycerol.<br><br>
DOI: 10.6084/m9.figshare.11320463
title: suppl. data

description: gene expression analysis
DOI: 10.6084/m9.figshare.11320463.v1
title: suppl. data

description: gene expression analysis
DOI: 10.6084/m9.figshare.11320388
title: Comprehensive single-PCR 16S and 18S rRNA community analysis validated with mock communities and denoising algorithms

description: This project includes 1) 18S mock communities amplified with 515Y/926R, V4F/V4R, and V4/V4RB primers and 2) Microbial communities collected from 1.2-80um size fraction at SPOT in 2014.
DOI: 10.6084/m9.figshare.11320361
title: Dataset for: Human microRNA-30 Inhibits Influenza Virus Infection by Suppressing the Expression of SOCS1, SOCS3, and NEDD4

description: Influenza A virus (IAV) has evolved multiple mechanisms to compromise type I interferon (IFN) responses. The antiviral function of interferon is mainly exerted by activating the JAK/STAT signaling and subsequently inducing interferon-stimulated genes (ISGs) production. However, the mechanism by which IAV combat the type I IFN signaling pathway is not fully elucidated. In the present study, we explored the roles of human microRNAs modulated by IAV infection in type I interferon (IFN) responses. We demonstrated that microRNA-30 (miR-30) family members were downregulated by IAV infection. Our data showed that the forced expression of miR-30 family members inhibited IAV proliferation, while miR-30 family members inhibitors promoted IAV proliferation. Mechanistically, we found that miR-30 family members targeted and reduced SOCS1 and SOCS3 expression, and thus relieved their inhibiting effects on IFN/JAK/STAT signaling pathway. In addition, miR-30 family members inhibited the expression of NEDD4, a negative regulator of IFITM3, which is important for host defense against influenza viruses. Our findings suggest that IAV utilizes a novel strategy to restrain host type I IFN-mediated antiviral immune responses by decreasing the expression of miR-30 family members, and add a new way to understand the mechanism of immune escape caused by influenza viruses.
DOI: 10.6084/m9.figshare.11320388.v1
title: Comprehensive single-PCR 16S and 18S rRNA community analysis validated with mock communities and denoising algorithms

description: This project includes 1) 18S mock communities amplified with 515Y/926R, V4F/V4R, and V4/V4RB primers and 2) Microbial communities collected from 1.2-80um size fraction at SPOT in 2014.