cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.17185840.v1
title: Updates on the chemistry, processing characteristics, and utilization of tea flavonoids in last two decades (2001-2021)

description: Tea flavonoids are widely recognized as critical flavor contributors and crucial health-promoting bioactive compounds, and have long been the focus of research worldwide in food science. The aim of this review paper is to summarize the major progress in tea flavonoid chemistry, their dynamics of constituents and concentrations during tea processing as well as storage, and their health functions studied between 2001 and 2021. Moreover, the utilization of tea flavonoids in the human body has also been discussed for a detailed understanding of their uptake, metabolism, and interaction with the gut microbiota. Many novel tea flavonoids have been identified, including novel A- and B-ring substituted flavan-3-ol derivatives, condensed and oxidized flavan-3-ol derivatives, and glycosylated and methylated flavonoids, and are found to be closely associated with the characteristic color, flavor, and health benefits of tea. Flavoalkaloids exist widely in various teas, particularly 8-<i>C N</i>-ethyl-2-pyrrolidinone-substituted flavan-3-ols. Tea flavonoids behave significantly difference in constituents and concentrations depending on tea cultivars, plantation conditions, multiple stresses, the tea-specified manufacturing steps, and even the long-term storage period. Tea flavonoids exhibit multiple health-promoting effects, particularly their anti-inflammatory in alleviating metabolic syndromes. Interaction of tea flavonoids with the gut microbiota plays vital roles in their health function.
DOI: 10.25721/5n1b-0738
title: Marche "Monte là-dessus"
DOI: 10.6084/m9.figshare.17185840
title: Updates on the chemistry, processing characteristics, and utilization of tea flavonoids in last two decades (2001-2021)

description: Tea flavonoids are widely recognized as critical flavor contributors and crucial health-promoting bioactive compounds, and have long been the focus of research worldwide in food science. The aim of this review paper is to summarize the major progress in tea flavonoid chemistry, their dynamics of constituents and concentrations during tea processing as well as storage, and their health functions studied between 2001 and 2021. Moreover, the utilization of tea flavonoids in the human body has also been discussed for a detailed understanding of their uptake, metabolism, and interaction with the gut microbiota. Many novel tea flavonoids have been identified, including novel A- and B-ring substituted flavan-3-ol derivatives, condensed and oxidized flavan-3-ol derivatives, and glycosylated and methylated flavonoids, and are found to be closely associated with the characteristic color, flavor, and health benefits of tea. Flavoalkaloids exist widely in various teas, particularly 8-<i>C N</i>-ethyl-2-pyrrolidinone-substituted flavan-3-ols. Tea flavonoids behave significantly difference in constituents and concentrations depending on tea cultivars, plantation conditions, multiple stresses, the tea-specified manufacturing steps, and even the long-term storage period. Tea flavonoids exhibit multiple health-promoting effects, particularly their anti-inflammatory in alleviating metabolic syndromes. Interaction of tea flavonoids with the gut microbiota plays vital roles in their health function.
DOI: 10.25721/z17h-2705
title: Considérations sur le deuil des musiciens
DOI: 10.5281/zenodo.5776012
title: Dataset related to article "Inhibition of tumor-associated macrophages by trabectedin improves the antitumor adaptive immunity in response to anti-PD-1 therapy"

description: This record contains data related to article “Inhibition of tumor-associated macrophages by trabectedin improves the antitumor adaptive immunity in response to anti-PD-1 therapy". A considerable proportion of cancer patients are resistant or only partially responsive to immune checkpoint blockade immunotherapy. Tumor-Associated Macrophages (TAMs) infiltrating the tumor stroma suppress the adaptive immune responses and, hence, promote tumor immune evasion. Depletion of TAMs or modulation of their protumoral functions is actively pursued, with the purpose of relieving this state of immunesuppression. We previously reported that trabectedin, a registered antitumor compound, selectively reduces monocytes and TAMs in treated tumors. However, its putative effects on the adaptive immunity are still unclear. In this study, we investigated whether treatment of tumor-bearing mice with trabectedin modulates the presence and functional activity of T-lymphocytes. In treated tumors, there was a significant upregulation of T cell-associated genes, including CD3, CD8, perforin, granzyme B, and IFN-responsive genes (MX1, CXCL10, and PD-1), indicating that T lymphocytes were activated after treatment. Notably, the mRNA levels of the Pdcd1 gene, coding for PD-1, were strongly increased. Using a fibrosarcoma model poorly responsive to PD-1-immunotherapy, treatment with trabectedin prior to anti-PD-1 resulted in improved antitumor efficacy. In conclusion, pretreatment with trabectedin enhances the therapeutic response to checkpoint inhibitor-based immunotherapy. These findings provide a good rational for the combination of trabectedin with immunotherapy regimens.
DOI: 10.5281/zenodo.5776011
title: Dataset related to article "Inhibition of tumor-associated macrophages by trabectedin improves the antitumor adaptive immunity in response to anti-PD-1 therapy"

description: This record contains data related to article “Inhibition of tumor-associated macrophages by trabectedin improves the antitumor adaptive immunity in response to anti-PD-1 therapy". A considerable proportion of cancer patients are resistant or only partially responsive to immune checkpoint blockade immunotherapy. Tumor-Associated Macrophages (TAMs) infiltrating the tumor stroma suppress the adaptive immune responses and, hence, promote tumor immune evasion. Depletion of TAMs or modulation of their protumoral functions is actively pursued, with the purpose of relieving this state of immunesuppression. We previously reported that trabectedin, a registered antitumor compound, selectively reduces monocytes and TAMs in treated tumors. However, its putative effects on the adaptive immunity are still unclear. In this study, we investigated whether treatment of tumor-bearing mice with trabectedin modulates the presence and functional activity of T-lymphocytes. In treated tumors, there was a significant upregulation of T cell-associated genes, including CD3, CD8, perforin, granzyme B, and IFN-responsive genes (MX1, CXCL10, and PD-1), indicating that T lymphocytes were activated after treatment. Notably, the mRNA levels of the Pdcd1 gene, coding for PD-1, were strongly increased. Using a fibrosarcoma model poorly responsive to PD-1-immunotherapy, treatment with trabectedin prior to anti-PD-1 resulted in improved antitumor efficacy. In conclusion, pretreatment with trabectedin enhances the therapeutic response to checkpoint inhibitor-based immunotherapy. These findings provide a good rational for the combination of trabectedin with immunotherapy regimens.
DOI: 10.17632/r6mzjs36xz.1
title: Water quality and physical assessment of sungkilaw waterfalls in Zamboanga Norte, Philippines | JBES 2021

description: Zamboanga del Norte is often considered enigmatic as it has several secret mysteries waiting to be found. Sungkilaw Falls in Zamboanga Norte, Philippines is now listed as a tourist destination as it has proved to be one of Zamboanga Peninsula’s most famous tourist destinations. This study considered three streams using a single sampling technique to assess the fall's physical features and water quality initially. Studied water quality parameters were pH, temperature, biochemical oxygen demand (BOD), turbidity, total dissolved solids (TDS) using pre-calibrated portable meters. Total and fecal coliforms were also determined using the Multiple Tube Fermentation Technique to find out the presence of a member of the coliform group in groundwater and surface water. Overall, Sungkilaw falls water quality parameters are within the normal limit of the DENR standard showing no potential pollution. The presence of coliforms was detected in the bacteriological analysis of the water samples in all sampling stations. These results are possible because of the wastes that leach from industrial, animal, and domestic sewage in the streams. Present findings are preliminary and further analyses and monitoring may be essential.
DOI: 10.17632/n2rrc25d3b.1
title: The ACDSi 2014 - a decennial study on adolescents' somatic, motor, psychosocial development and healthy lifestyle

description: The ACDSi 2014 - a decennial study on adolescents' somatic, motor, psychosocial development and healthy lifestyle.
DOI: 10.25721/05zz-b939
title: Information sur Monsieur René Régis
DOI: 10.17632/5hxw582v9r.1
title: Cardiac metabolism in mice treated with FGF1- and CHIR99021-Loaded Nanofibers

description: This data set includes the abundance of metabolites of heart tissue of mice using Targeted Liquid Chromatography Tandem Mass Spectrometry. Both the positive and negative ionization mode were used for the metabolites detection.
DOI: 10.17632/jk25fx32nv.1
title: Bone pathologies of modern caprines (Ovis aries&Capra hircus) in the context of the pasture-stall system of the steppe zone of the South Urals (Russia)

description: The dataset contains the results of studying the pathologies of the modern population of caprines (ovis aries&Capra hircus) in the steppe zone of the Southern Urals
DOI: 10.17632/bxzt2fr4hg.1
title: Contamination of the shore of the Southeast Baltic (Kaliningrad Oblast, Russia) with the debris of geosynthetic materials for the period 2018 - 2020

description: The database gives information on the contamination of the shore of the Southeast Baltic with the debris of geosynthetic materials for the period 2018 - 2020. (ERANET-RUS_Plus joint project EI-GEO, ID 212 (RFBR 18-55-76002 ERA_a, BMBF 01DJ18005)
Fragments of geosynthetic materials (not smaller than 1 cm) were collected during continuous visual scanning assumed a continuous passage along the entire coastline by a group of three observers.

The first file [1 List_geosynthetic_debris_SEB.pdf] contains information about types of geosynthetic material debris found on the shore of the Kaliningrad Oblast (Russian, South-East Baltic) during field surveys in the 2018 - 2020.

The second folder [2 Monitoring_geosynthetic_debris_SEB] describes the data on the contamination of the beach strip with geosynthetic debris for the period 2018-2020 in MS Excel format (*.xlsx) and in CSV format (*.csv) for each year separately.

The third file [3 Scales_geosynthetic_debris_SEB.pdf] demonstrates the statistical distributions of the found geosynthetic debris by spatial size.

The fourth file [4 Monitoring Poland and Lithuania.pdf] contains information about the types of geosynthetic material debris found on the Polish and Lithuanian coasts adjacent to Kaliningrad Oblast (South-East Baltic) during field surveys in May-June 2019.
DOI: 10.17632/rdtcgstmps.1
title: Data for measuring impact of problem-based learning during learning mechanical waves: MWCS, VASS, RTOP

description: This data was collected on behalf of the first author doctoral thesis. It was collected from February to April 2021 in 19 secondary schools in Southwestern Uganda. Four hundred and nineteen Form-six physics students and 22 teachers were involved in the study. Three instruments were used to collect data:
1. Mechanical waves conceptual survey (MWCS)
2. Views about science survey (VASS), and
3. Refomed teaching observation protocol (RTOP).
DOI: 10.21223/p3/ylqunf
title: Dataset for: Standard Evaluation Trial for micronutrient content

description: Iron (Fe), zinc (Zn) and vitamins A and C are among the most widespread nutrient deficiencies in developing countries. Potato genotypes display from moderate to large ranges of mineral content. A survey of advanced breeding clones and cultivars showed broad range of iron contents extending from 18 to 65 μg/g DW, while less overall variation of Zinc contents was true, ranging from 12.5 to 20 μg/g DW. Some evidence of consistency of genotype effects across environments suggest that significant gains for iron and zinc can be expected through breeding, particularly for iron if coupled with a high content of vitamin C considering the close association between iron availability and vitamin C. Concentration of vitamin C in potatoes is moderate to low compared with fruits and other vegetables, yet as a staple food, potatoes may be one of the highest contributors of vitamin C in the diets of people in many places around the world. Inheritance study using low and high concentration parents suggested that vitamin C concentration in tubers is highly heritable and hence increased levels could rapidly be achieved through selection of high concentration parents Standard evaluation trials assessed iron, zinc and vitamin C contents in tuber samples from advanced breeding clones to document their nutritional values. Healthy and representative tubers with regard to tuber size of each clone are picked up from plots of two replications of 10 hill plots from trials conducted in pathogen and pest protected fields and grown following local procedures. Iron and Zinc content are determined by inductively coupled plasma–optical emission spectrophotometry (ICP) and concentrations expressed in mg/kg, dry weight (DW), while vitamin C is quantified by the spectrophotometric method and expressed in mg/100 g, fresh weight (FW).
DOI: 10.17632/pp73wghmhm.2
title: Supplementary material

description: In this supplementary material we find supplementary material on the methods used to select the comparative group and the exclusion criteria used in this study. In addition, the variables collected in the study are reflected.
DOI: 10.25721/qskr-6325
title: Polka piquée "Le taisson"
DOI: 10.17632/d87vg86zd8.1
title: Risom et al., "Transition to invasive breast cancer is associated with progressive changes in the structure and composition of tumor stroma"

description: Single channel MIBI images for each patient, annotated single-cell data, tissue feature results, and code to perform all analyses in the manuscript "Transition to invasive breast cancer is associated with progressive changes in the structure and composition of tumor stroma".
DOI: 10.15468/pff4z5
title: Three new species of Sternaspidae (Annelida: Sedentaria) from Thailand

description: This dataset contains the digitized treatments in Plazi based on the original journal article Plathong, Jintana, Plathong, Sakanan, Salazar-Vallejo, Sergio I. (2021): Three new species of Sternaspidae (Annelida: Sedentaria) from Thailand. Zootaxa 5081 (3): 373-388, DOI: https://doi.org/10.11646/zootaxa.5081.3.4
DOI: 10.5281/zenodo.5776547
title: Dataset related to article "Biologic therapies for plaque type psoriasis in patients with previous malignant cancer: longterm safety in a single- center real-life population"

description: This record contains data related to article "Biologic therapies for plaque type psoriasis in patients with previous malignant cancer: longterm safety in a single- center real-life population" ABSTRACT Introduction: This is an Italian single-center retrospective study evaluating safety and efficacy of biologic agents in psoriatic patients with a previous diagnosis of malignant cancer. Aim: Management of moderate and severe psoriasis patients with a past medical history of malignancies could be difficult because biologic agents are historically associated with a presumptive increased risk of neoplastic reactivation or of a new incoming cancer. The aim of this study is to assess the safety of biologics in patients with a previous cancer diagnosis. Material and methods: The study analyzed 16 moderate to severe psoriasis patients with a diagnosis of malignant cancer in the previous 10 years treated with biologic agents for up to at least 96 weeks. In five of these patients, cancer was diagnosed in the previous 5 years. Results: We observed a rapid decrease in PASI (psoriasis area severity index) reaching a 90% improvement in 100% of patients. Oncologic follow up did not show any worsening or reactivation of cancer during the entire observation period. No new malignancies were observed in the analyzed sample. Conclusions: Biologic agents in our experience have demonstrated to be safe and effective in psoriatic patients with a past medical history of malignant cancer.
DOI: 10.5281/zenodo.5776546
title: Dataset related to article "Biologic therapies for plaque type psoriasis in patients with previous malignant cancer: longterm safety in a single- center real-life population"

description: This record contains data related to article "Biologic therapies for plaque type psoriasis in patients with previous malignant cancer: longterm safety in a single- center real-life population" ABSTRACT Introduction: This is an Italian single-center retrospective study evaluating safety and efficacy of biologic agents in psoriatic patients with a previous diagnosis of malignant cancer. Aim: Management of moderate and severe psoriasis patients with a past medical history of malignancies could be difficult because biologic agents are historically associated with a presumptive increased risk of neoplastic reactivation or of a new incoming cancer. The aim of this study is to assess the safety of biologics in patients with a previous cancer diagnosis. Material and methods: The study analyzed 16 moderate to severe psoriasis patients with a diagnosis of malignant cancer in the previous 10 years treated with biologic agents for up to at least 96 weeks. In five of these patients, cancer was diagnosed in the previous 5 years. Results: We observed a rapid decrease in PASI (psoriasis area severity index) reaching a 90% improvement in 100% of patients. Oncologic follow up did not show any worsening or reactivation of cancer during the entire observation period. No new malignancies were observed in the analyzed sample. Conclusions: Biologic agents in our experience have demonstrated to be safe and effective in psoriatic patients with a past medical history of malignant cancer.
DOI: 10.25721/1m0q-0d53
title: Valse-Vienne
DOI: 10.17632/pwybbtgrbk.2
title: Fecal microbiota from MRL/Lpr mice exacerbates pristane induced lupus

description: Object: To investigate the influences of the fecal microbiota transplantation from the MRL strains on the pristane-induced lupus mice from the phenotypic, immunological and microbial aspects.

The following data include the figures and tables presented in the manuscript and supplementary files as well as the original data relevant with the figures.
DOI: 10.17632/9k9x4d7jvy.1
title: Can you accurately monitor your behaviors while multitasking? The effect of media multitasking on metacognition

description: The effect of media multitasking on metacognition
DOI: 10.7294/14448027.v5
title: Vortex patterns in the wake of an oscillating cylinder in a flowing soap film

description: This data set contains video recordings of flow visualization experiments conducted in an inclined gravity-driven soap film channel, in which a cylinder was transversely oscillated at specific frequencies and amplitudes. Each video corresponds to a single experiment conducted at a certain non-dimensional frequency and amplitude.
DOI: 10.17632/gnyrym4mv4.2
title: Code & data — Further improvement of bending performance for conditioning covariance matrices

description: A Jupyter Notebook (.ipynb) and its corresponding Rmarkdown (.rmd) and HTML (.html) files are provided. It provides code to produce the data, code to produce the results, and the results. Different bending procedures are compared based on the modification of eigenvalues. An updated bending procedure is presented, in which not only the eigenvalues smaller than a small positive value (Ɛ) are changed to Ɛ, but the smallest eigenvalue greater than Ɛ is gradually reduced as long as the bending performance is improved (reduced average absolute deviation between the upper triangle elements of the original matrix and the bent matrix).
DOI: 10.6084/m9.figshare.17185895
title: asignacion3-prueba3-IBOS249

description: USA boundary dissolved, roads, and global cities.<br>
DOI: 10.6084/m9.figshare.17185895.v1
title: asignacion3-prueba3-IBOS249

description: USA boundary dissolved, roads, and global cities.<br>
DOI: 10.17632/6422xdykvm.1
title: Date for Lunpola Basin

description: Date for Lunpola Basin
DOI: 10.17632/27pdfr7mzh.1
title: Functional Constipation in South Asia

description: De-identified survey data.
DOI: 10.17632/5rzx2gj766.1
title: E-GOVERNMENT TEXT MINING DATA IN WUHAN

description: •	The dataset is sourced from the local e-government panel in China: Wuhan City Message Board.
•	This dataset provides messages of the most pressing public issues about COVID-19 that Wuhan people want the government to address.
•	This data is listed in chronological order, which can reflect the change of public opinion.
•	The data can be used for text mining. The scores of sentiment analysis can be used to reflect the change and high and low distribution of the mood of the Wuhan people.
•	Semantic analysis and Word2vec analysis of this data can get the topic distribution of Wuhan people by the stage of time.
•	The public and policymakers can use these changes in sentiment and themes to know what situation they are in, in the postnormal triggered by COVID-19.
DOI: 10.17632/nc7sjkwryp.1
title: teacher attention

description: the importance of teacher attention has been emphasized by education administra-tors, educators, education researchers and the public
DOI: 10.17632/c2d2tbvfjs.1
title: Neoarchean deep subduction (>200 km) due to the Wilson-cycle type plate tectonics: Evidence from coesite and supersilicic K-pyroxene in diamondiferous kimberlite-borne eclogite xenolith from Dharwar craton, India - Garnet and clinopyroxene data

description: The Excel files contain mineral chemical data of garnet and clinopyroxene used in Figure 3a and 3b.  The word file contains full references of the data used in Figure 3a and 3b.
DOI: 10.17632/wsprs2fwh8.1
title: MANAGING THE SUPPLY CHAIN RELATIONSHIP AND THE KEY DRIVING FACTORS

description: Supply chain relationships (SCR) involve buyers and suppliers from many different companies. This study aims to explain the relationship between Information System (IS), Logistics Service Quality (LSQ), Social Value and Ethics (SVE) empirically, and their effect on SCR. This research is a survey research, the questionnaires are distributed online and the answers are collected from 160 respondents. Data analysis was performed using structural equation modeling (SEM) with Amos 24 software and IBM SPSS Statistics 26. Five hypotheses were proposed, four were supported and one was not proven, where LSQ had no effect on SCR. IS is a definite tool for businesses to use for ease, convenience and speed of service to improve LSQ and SCR. This study presents SVE as the basic foundation, a well-executed SVE will certainly increase LSQ and SCR. This paper serves as a feedback loop that provides insight into the empirical evidence from the SCR study.