cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.16567461.v1
title: TableS2 - Discovery of Thymosin Beta-4 as a Human Exerkine and Growth Factor

description: Skeletal muscle is an endocrine organ secreting exercise-induced factors (exerkines), which play a pivotal role in inter-organ crosstalk. Using mass spectrometry (MS)-based proteomics, we characterized the secretome and identified thymosin beta-4 (TMSB4X) as the most upregulated secreted protein in the media of contracting C2C12 myotubes. TMSB4X was also acutely increased in plasma of exercising humans irrespective of the insulin resistance condition or exercise mode. Treatment of mice with TMSB4X did not ameliorate the metabolic disruptions associated with diet induced-obesity, nor did it enhance muscle regeneration <i>in vivo</i>. However, TMSB4X increased osteoblast proliferation and neurite outgrowth, consistent with its WADA-classification as a prohibited growth factor. Therefore, we report TMSB4X as a human exerkine with a potential role in cellular crosstalk.<br>The data contain the supplementary table 2.
DOI: 10.6084/m9.figshare.16567485.v2
title: TableS3 Conditioned media proteome (secretome) from EPS-stimulated C2C12 myotubes and their controls prior to imputation.

description: <b>Discovery of Thymosin Beta-4 as a Human Exerkine and Growth Factor</b><br>Skeletal muscle is an endocrine organ secreting exercise-induced factors (exerkines), which play a pivotal role in inter-organ crosstalk. Using mass spectrometry (MS)-based proteomics, we characterized the secretome and identified thymosin beta-4 (TMSB4X) as the most upregulated secreted protein in the media of contracting C2C12 myotubes. TMSB4X was also acutely increased in plasma of exercising humans irrespective of the insulin resistance condition or exercise mode. Treatment of mice with TMSB4X did not ameliorate the metabolic disruptions associated with diet induced-obesity, nor did it enhance muscle regeneration <i>in vivo</i>. However, TMSB4X increased osteoblast proliferation and neurite outgrowth, consistent with its WADA-classification as a prohibited growth factor. Therefore, we report TMSB4X as a human exerkine with a potential role in cellular crosstalk.<br>The data contain: <b>TableS3</b> Conditioned media proteome (secretome) from EPS-stimulated C2C12 myotubes and their controls prior to imputation.
DOI: 10.6084/m9.figshare.16567485
title: TableS3 Conditioned media proteome (secretome) from EPS-stimulated C2C12 myotubes and their controls prior to imputation.

description: <b>Discovery of Thymosin Beta-4 as a Human Exerkine and Growth Factor</b><br>Skeletal muscle is an endocrine organ secreting exercise-induced factors (exerkines), which play a pivotal role in inter-organ crosstalk. Using mass spectrometry (MS)-based proteomics, we characterized the secretome and identified thymosin beta-4 (TMSB4X) as the most upregulated secreted protein in the media of contracting C2C12 myotubes. TMSB4X was also acutely increased in plasma of exercising humans irrespective of the insulin resistance condition or exercise mode. Treatment of mice with TMSB4X did not ameliorate the metabolic disruptions associated with diet induced-obesity, nor did it enhance muscle regeneration <i>in vivo</i>. However, TMSB4X increased osteoblast proliferation and neurite outgrowth, consistent with its WADA-classification as a prohibited growth factor. Therefore, we report TMSB4X as a human exerkine with a potential role in cellular crosstalk.<br>The data contain: <b>TableS3</b> Conditioned media proteome (secretome) from EPS-stimulated C2C12 myotubes and their controls prior to imputation.
DOI: 10.6084/m9.figshare.16567485.v1
title: TableS3 - Discovery of Thymosin Beta-4 as a Human Exerkine and Growth Factor

description: Skeletal muscle is an endocrine organ secreting exercise-induced factors (exerkines), which play a pivotal role in inter-organ crosstalk. Using mass spectrometry (MS)-based proteomics, we characterized the secretome and identified thymosin beta-4 (TMSB4X) as the most upregulated secreted protein in the media of contracting C2C12 myotubes. TMSB4X was also acutely increased in plasma of exercising humans irrespective of the insulin resistance condition or exercise mode. Treatment of mice with TMSB4X did not ameliorate the metabolic disruptions associated with diet induced-obesity, nor did it enhance muscle regeneration <i>in vivo</i>. However, TMSB4X increased osteoblast proliferation and neurite outgrowth, consistent with its WADA-classification as a prohibited growth factor. Therefore, we report TMSB4X as a human exerkine with a potential role in cellular crosstalk.<br>The data contain the supplementary table 3.
DOI: 10.6084/m9.figshare.16567500
title: TableS4. 1D enrichment for GOBP and GOCC of log-fold change (EPS vs Ctrl) in the secretome.

description: <b>Discovery of Thymosin Beta-4 as a Human Exerkine and Growth Factor</b><br>Skeletal muscle is an endocrine organ secreting exercise-induced factors (exerkines), which play a pivotal role in inter-organ crosstalk. Using mass spectrometry (MS)-based proteomics, we characterized the secretome and identified thymosin beta-4 (TMSB4X) as the most upregulated secreted protein in the media of contracting C2C12 myotubes. TMSB4X was also acutely increased in plasma of exercising humans irrespective of the insulin resistance condition or exercise mode. Treatment of mice with TMSB4X did not ameliorate the metabolic disruptions associated with diet induced-obesity, nor did it enhance muscle regeneration <i>in vivo</i>. However, TMSB4X increased osteoblast proliferation and neurite outgrowth, consistent with its WADA-classification as a prohibited growth factor. Therefore, we report TMSB4X as a human exerkine with a potential role in cellular crosstalk.<br>The data contain:<b>TableS4.</b> 1D enrichment for GOBP and GOCC of log-fold change (EPS vs Ctrl) in the secretome.<br>
DOI: 10.6084/m9.figshare.16567500.v2
title: TableS4. 1D enrichment for GOBP and GOCC of log-fold change (EPS vs Ctrl) in the secretome.

description: <b>Discovery of Thymosin Beta-4 as a Human Exerkine and Growth Factor</b><br>Skeletal muscle is an endocrine organ secreting exercise-induced factors (exerkines), which play a pivotal role in inter-organ crosstalk. Using mass spectrometry (MS)-based proteomics, we characterized the secretome and identified thymosin beta-4 (TMSB4X) as the most upregulated secreted protein in the media of contracting C2C12 myotubes. TMSB4X was also acutely increased in plasma of exercising humans irrespective of the insulin resistance condition or exercise mode. Treatment of mice with TMSB4X did not ameliorate the metabolic disruptions associated with diet induced-obesity, nor did it enhance muscle regeneration <i>in vivo</i>. However, TMSB4X increased osteoblast proliferation and neurite outgrowth, consistent with its WADA-classification as a prohibited growth factor. Therefore, we report TMSB4X as a human exerkine with a potential role in cellular crosstalk.<br>The data contain:<b>TableS4.</b> 1D enrichment for GOBP and GOCC of log-fold change (EPS vs Ctrl) in the secretome.<br>
DOI: 10.6084/m9.figshare.16567500.v1
title: TableS4 - Discovery of Thymosin Beta-4 as a Human Exerkine and Growth Factor

description: Skeletal muscle is an endocrine organ secreting exercise-induced factors (exerkines), which play a pivotal role in inter-organ crosstalk. Using mass spectrometry (MS)-based proteomics, we characterized the secretome and identified thymosin beta-4 (TMSB4X) as the most upregulated secreted protein in the media of contracting C2C12 myotubes. TMSB4X was also acutely increased in plasma of exercising humans irrespective of the insulin resistance condition or exercise mode. Treatment of mice with TMSB4X did not ameliorate the metabolic disruptions associated with diet induced-obesity, nor did it enhance muscle regeneration <i>in vivo</i>. However, TMSB4X increased osteoblast proliferation and neurite outgrowth, consistent with its WADA-classification as a prohibited growth factor. Therefore, we report TMSB4X as a human exerkine with a potential role in cellular crosstalk.<br>The data contain the supplementary table 4.
DOI: 10.6084/m9.figshare.13634912
title: Canadian Salmonella Heidelberg Genome fastas from 2013

description: This collection includes 430 files in fasta format. Each file corresponds to one assembled genome of Salmonella Heidelberg. All samples were originally collected in 2013, in Ontario Canada. Samples were collected and processed by the Canadian Food Inspection Agency, the Canadian Integrated Program for Antimicrobial Resistance Surveillance, and the Public Health Ontario Laboratory.
DOI: 10.5281/zenodo.4720663
title: Last Interglacial sea-level proxies in the Western Atlantic and Southwestern Caribbean, from Brazil to Honduras

description: This spreadsheet is a complete record of the Last Interglacial sea-level proxies in the Western Atlantic and Southwestern Caribbean, from Brazil to Honduras. It has been exported from "The World Atlas of Last Interglacial Shorelines (WALIS) Database" (https://warmcoasts.eu/world-atlas.html).
DOI: 10.5063/bg2mdz
title: Pan-Amazon Basins: A spatial Framework for the Conservation of Aquatic Ecosystems in the Amazon-Orinoco-Guianas Region

description: This database is composed of a hierarchical system of watersheds organized in twelve levels, with spatial coverage for the so-called Pan-Amazon region that contains the Amazon, Tocantins, Guianas, Orinoco, Paranaíba, Paraná headwaters, and coastal basins north and south of the mouth of the Amazon River. The system has 142,572 basins at the most detailed level (BL 12), with an average size of 6541 ha. The base follows the logic of SNAPP (Venticinque et al 2016) that considers the delineation of the main stem for the main rivers of each basin at levels 1 and 2. For making this base we used the elevation, flow direction, and flow accumulation files from MERIT Hydro (Yamashida et al 2019). The analyses were performed in ArcHydro 2.0 within ArcGis 10.1. After deriving the basins and defining the mainstem areas, the integrated tool was applied to simplify the geometry of the basin boundaries jointly between the 12 levels. Finally, a geodatabase was generated containing the 12 basin levels provided here.
DOI: 10.5519/qd.vhj49rbf
title: Query on the Natural History Museum Data Portal (data.nhm.ac.uk) (366955 records)
DOI: 10.5281/zenodo.5516457
title: E-scooters: competition with shared bicycles and relationship to public transport (processed datasets)

description: Processed datasets for article "E-scooters: competition with shared bicycles and relationship to public transport" by Łukasz Nawaro (University of Warsaw, Faculty of Economic Sciences).
description: This work was supported by the National Science Centre, Poland : Project number 2019/35/N/HS4/01976.
DOI: 10.5281/zenodo.5516456
title: E-scooters: competition with shared bicycles and relationship to public transport (processed datasets)

description: Processed datasets for article "E-scooters: competition with shared bicycles and relationship to public transport" by Łukasz Nawaro (University of Warsaw, Faculty of Economic Sciences).
description: This work was supported by the National Science Centre, Poland : Project number 2019/35/N/HS4/01976.
DOI: 10.6084/m9.figshare.16641358
title: Flatten_the_curve.csv

description: This dataset is used to reproduce the results of the paper "Flatten the Curve: Empirical Evidence on How Non-Pharmaceutical Interventions Substituted Pharmaceutical Treatments during COVID-19 Pandemic".
DOI: 10.6084/m9.figshare.16641358.v1
title: Flatten_the_curve.csv

description: This dataset is used to reproduce the results of the paper "Flatten the Curve: Empirical Evidence on How Non-Pharmaceutical Interventions Substituted Pharmaceutical Treatments during COVID-19 Pandemic".
DOI: 10.6084/m9.figshare.16641448
title: Dataset - Nursing students admitted through the affirmative action system display similar performance in professional and academic trajectories to those from the regular path in a public school in Brazil

description: These files represent the raw data collected in this research.
DOI: 10.6084/m9.figshare.16641448.v1
title: Dataset - Nursing students admitted through the affirmative action system display similar performance in professional and academic trajectories to those from the regular path in a public school in Brazil

description: These files represent the raw data collected in this research.
DOI: 10.5281/zenodo.5516503
title: Case studies of a multi-product and multiple-sources slurry pipeline network scheduling problem in the phosphate industry

description: The data shared summarises two case studies of a multi-product and multiple-sources slurry pipeline network scheduling problem in the phosphate industry.
DOI: 10.5281/zenodo.5516502
title: Case studies of a multi-product and multiple-sources slurry pipeline network scheduling problem in the phosphate industry

description: The data shared summarises two case studies of a multi-product and multiple-sources slurry pipeline network scheduling problem in the phosphate industry.
DOI: 10.5281/zenodo.5516522
title: A highly accurate and constrained density functional obtained with differentiable programming

description: Set of data and codes needed to reproduce the manuscript : "A highly accurate and constrained density functional obtained with differentiable programming"
DOI: 10.5281/zenodo.5516521
title: A highly accurate and constrained density functional obtained with differentiable programming

description: Set of data and codes needed to reproduce the manuscript : "A highly accurate and constrained density functional obtained with differentiable programming"
DOI: 10.6082/uchicago.3317
title: Data for Evolving CO2 in ExoCAM

description: Here are the data and scripts used for creating all the 9 figures in the paper, "Evolving CO$_2$ rather than SST leads to a factor of ten decrease in GCM convergence time".
DOI: 10.25345/c55v8q
title: MassIVE MSV000088121 - GBS S protein Supernatant Proteomics
title: Quantitative proteomics analysis of Group B Streptococcus strains
DOI: 10.6084/m9.figshare.16641508
title: Entrepreneurship education curriculum

description: Entrepreneurship education curriculum <br>
DOI: 10.25345/c5225q
title: MassIVE MSV000088122 - Northern elephant seal skeletal muscle, blubber, and plasma proteome responses to prolonged fasting
title: Northern elephant seal skeletal muscle, blubber, and plasma were collected from 5 adult females early and late in a 5-week molting fast (mean 33 days apart; see Sample Key in supplementary files). Proteins were isolated from muscle using the Trizol method and blubber using Qiazol with the Qiagen RNeasy Lipid Mini kit (see Khudyakov et al., 2018, doi: 10.1242/bio.036731). Plasma samples were used raw (without depletion of highly abundant proteins). Muscle, blubber, and plasma proteins were denatured using 1% sodium deoxycholate, 8 M urea, and 5 mM DTT in 50 mM ammonium bicarbonate and digested in-solution using trypsin (1:50 trypsin to protein ratio).
DOI: 10.6084/m9.figshare.16641505.v1
title: Supplemental Table 1.

description: Characteristics of patients with <i>SGPL1</i> mutations
DOI: 10.6084/m9.figshare.16641520.v1
title: Supplemental Table 2.

description: Characteristics of PAI patients with unknown molecular etiology
DOI: 10.6084/m9.figshare.16641523.v1
title: Supplemental Table 3.

description: Comparison of clinical and biochemical characteristics of PAI patients with solved or unsolved etiology
DOI: 10.6084/m9.figshare.16641535.v1
title: Supplemental Table 4.

description: Comparison of adrenal steroids of non-CAH PAI patients with identified molecular etiologies causing isolated glucocorticoid (patients with MC2R, MRAP and NNT mutations) vs glucocorticoid+mineralocorticoid+sex steroid deficiency (patients with StAR, CYP11A1, SGPL1, ABCD1, AAAS, NR0B1/DAX1, AIRE mutations).
DOI: 10.6084/m9.figshare.16641544.v1
title: Supplemental Table 5.

description: Adrenal steroid hormones of non-CAH PAI patients with identified molecular etiologies compared to control group
DOI: 10.6084/m9.figshare.16641517
title: Seurat_object_whole_Mouse_Thymus

description: This item comprises each 4 ADT- and RNA-libraries: two for 3 month-old Mice (THY1, THY2), two for 12 month-old Mice (THY3, THY4).
DOI: 10.6084/m9.figshare.16641517.v1
title: Seurat_object_whole_Mouse_Thymus

description: This item comprises each 4 ADT- and RNA-libraries: two for 3 month-old Mice (THY1, THY2), two for 12 month-old Mice (THY3, THY4).
DOI: 10.6084/m9.figshare.16641565.v1
title: Dingxiang Doctor tweets data

description: Processed data extracted from weibo of Dingxiang Doctor
DOI: 10.6084/m9.figshare.16641565
title: Dingxiang Doctor tweets data

description: Processed data extracted from weibo of Dingxiang Doctor
DOI: 10.5281/zenodo.5513081
title: Rosetta Loop Modeling Data for "A Systematic Approach for Evaluating the Role of Surface-Exposed Loops in Trypsin-like Serine Proteases: Analysis of the 170 loop in Coagulation Factor VIIa"

description: Rosetta Loop Modeling data for the publication "A Systematic Approach for Evaluating the Role of Surface-Exposed Loops in Trypsin-like Serine Proteases: Analysis of the 170 loop in Coagulation Factor VIIa." See the included readme.txt for more details. Please cite the paper if you use these data.
DOI: 10.5281/zenodo.5513080
title: Rosetta Loop Modeling Data for "A Systematic Approach for Evaluating the Role of Surface-Exposed Loops in Trypsin-like Serine Proteases: Analysis of the 170 loop in Coagulation Factor VIIa"

description: Rosetta Loop Modeling data for the publication "A Systematic Approach for Evaluating the Role of Surface-Exposed Loops in Trypsin-like Serine Proteases: Analysis of the 170 loop in Coagulation Factor VIIa." See the included readme.txt for more details. Please cite the paper if you use these data.
DOI: 10.5517/ccdc.csd.cc284bkb
title: CCDC 2089541: Experimental Crystal Structure Determination

description: Related Article: D.S. Ajisha, R. Ezhil Vizhi|2021|J.Mol.Struct.|1248|131426|doi:10.1016/j.molstruc.2021.131426
DOI: 10.17632/9j9cbr59jv.1
title: A new method for dating impact events - thermal dependency on nanoscale Pb mobility in monazite shock twins - Research data

description: Atom probe data
DOI: 10.15139/s3/ekdfdl
title: Data for: Caregiver social support and child toilet training in rural Odisha, India: what types of support facilitate training and how?

description: De-identified data for "Sclar, G.D. Mosler, H-J. Caregiver social support and child toilet training in rural Odisha, India: what types of support facilitate training and how? Applied Psychology: Health and Well-being." This cross-sectional study examined the role of social support in child toilet training using mediation and conditional process analyses. The dataset includes survey responses from caregivers of children 5 years old living in Ganjam and Gajapati districts in Odisha, India. Data was collected between December 2019 - February 2020.
DOI: 10.5281/zenodo.4886698
title: Data files for: Huston, D.C. et al. 2021. Stable isotope signatures of an acanthocephalan and trematode from the herbivorous marine fish Kyphosus bigibbus (Perciformes: Kyphosidae). Journal of Parasitology. 107: 726–730

description: Data files for the paper: Huston, D.C. et al. 2021. Stable isotope signatures of an acanthocephalan and trematode from the herbivorous marine fish Kyphosus bigibbus (Perciformes: Kyphosidae). Journal of Parasitology. 107(5) 726–730 Includes raw data, .csv files for import of data into R, R script file, and excel spreadsheet file used to create Figure 1.
DOI: 10.5281/zenodo.4886697
title: Data files for: Huston, D.C. et al. 2021. Stable isotope signatures of an acanthocephalan and trematode from the herbivorous marine fish Kyphosus bigibbus (Perciformes: Kyphosidae). Journal of Parasitology. 107: 726–730

description: Data files for the paper: Huston, D.C. et al. 2021. Stable isotope signatures of an acanthocephalan and trematode from the herbivorous marine fish Kyphosus bigibbus (Perciformes: Kyphosidae). Journal of Parasitology. 107(5) 726–730 Includes raw data, .csv files for import of data into R, R script file, and excel spreadsheet file used to create Figure 1.
DOI: 10.5519/qd.gln5otha
title: Query on the Natural History Museum Data Portal (data.nhm.ac.uk) (303 records)
DOI: 10.3886/e113541v1-96540
title: Replication data for: Disease and Gender Gaps in Human Capital Investment: Evidence from Niger's 1986 Meningitis Epidemic

description: This paper examines whether disease burdens, especially prevalent in the tropics, contribute significantly to widening gender gaps in educational attainment. We estimate the impact of sudden exposure to the 1986 meningitis epidemic in Niger on girls' education relative to boys. Our results suggest that increases in meningitis cases during epidemic years significantly reduce years of education disproportionately for primary school-aged going girls in areas with higher meningitis exposure. There is no significant effect for boys in the same cohort and no effects of meningitis exposure for non-epidemic years. Our findings have broader implications for climate-induced disease effects on social inequality.
DOI: 10.5281/zenodo.5516710
title: Meta Analysis of Conservation Games Data

description: This is the first release of Meta Analysis of Conservation Games Dataset. This was created for the analysis in the paper "Payments don't reconcile agriculture and conservation" by Andrew Reid Bell, O. Sarobidy Rakotonarivo, Apurva Bhargava, A. Bradley Duthie, Wei Zhang, Becca Sargent, Spike Lewis, and Adams Kipchumba.
DOI: 10.5281/zenodo.5516709
title: Meta Analysis of Conservation Games Data

description: This is the first release of Meta Analysis of Conservation Games Dataset. This was created for the analysis in the paper "Payments don't reconcile agriculture and conservation" by Andrew Reid Bell, O. Sarobidy Rakotonarivo, Apurva Bhargava, A. Bradley Duthie, Wei Zhang, Becca Sargent, Spike Lewis, and Adams Kipchumba.
DOI: 10.14457/tu.the.2018.902
title: การวิเคราะห์การตอบสนองของตลาดหลักทรัพย์แห่งประเทศไทยต่อเหตุการณ์สำคัญทางการเมือง: กรณีศึกษา ปี 2547-2561

description: งานวิจัยนี้มีวัตถุประสงค์เพื่อศึกษาผลกระทบของเหตุการณ์ทางการเมืองต่อผลตอบแทนของตลาดหลักทรัพย์แห่งประเทศไทยในช่วงปี 2547 – 2561 ซึ่งเป็นช่วงเวลาที่ประเทศประสบกับความไม่มั่นคงทางการเมืองเป็นระยะเวลา 15 ปีจากผลการศึกษาสรุปได้ว่า เหตุการณ์ประเภทการยุบสภาผู้แทนราษฎรส่งผลกระทบด้านลบต่อตลาดทั้งก่อนและหลังเกิดเหตุการณ์ เหตุการณ์ประเภทการเลือกตั้งส่งผลกระทบด้านลบต่อตลาดในช่วงก่อนเกิดเหตุการณ์แต่พลิกกลับมาเป็นบวกภายหลังเหตุการณ์เกิดขึ้นเหตุการณ์การเริ่มชุมนุมส่งผลกระทบด้านลบต่อตลาดในระยะสั้น ในขณะที่เหตุการณ์ยุติการชุมนุมทางการเมืองส่งผลกระทบด้านบวกต่อตลาดในระยะยาว และเหตุการณ์รัฐประหารส่งผลกระทบด้านลบต่อตลาดในช่วงระยะสั้นเท่านั้น
DOI: 10.5281/zenodo.5516726
title: Urban-PLUMBER: Flux tower data archive – SG-TelokKurau

description: Eddy covariance flux tower dataset from Telok Kurau, Singapore (March 2015 – Feb. 2016) for the URBAN-PLUMBER model evaluation project (https://urban-plumber.github.io/SG-TelokKurau/). Urban-PLUMBER evaluates the performance of land surface models used in meteorological or climatic simulations of urban areas (https://urban-plumber.github.io/).
DOI: 10.5281/zenodo.5516725
title: Urban-PLUMBER: Flux tower data archive – SG-TelokKurau

description: Eddy covariance flux tower dataset from Telok Kurau, Singapore (March 2015 – Feb. 2016) for the URBAN-PLUMBER model evaluation project (https://urban-plumber.github.io/SG-TelokKurau/). Urban-PLUMBER evaluates the performance of land surface models used in meteorological or climatic simulations of urban areas (https://urban-plumber.github.io/).