cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.17294138.v1
title: Supplementary Material for: Involvement of cannabinoid type 2 (CB2) receptors in the favorable effects of sumatriptan on the random-pattern skin flap survival in rats: a novel potential target

description: Introduction: Recent investigations have indicated the potential therapeutic role of cannabinoid type 2 (CB2) receptors in various inflammatory-related disorders. However, the role of these receptors has not been studied in skin flap models previously. In this study, we aimed to evaluate the possible involvement of CB2 receptors in the anti-inflammatory effects of sumatriptan and improvement of the random-pattern skin flap survival in rats. Methods: In a controlled experimental study, 36 male Wistar rats were randomly divided into six study groups (n = 6 per group). Two doses of sumatriptan (0.1 and 0.3 mg/kg) were administered intraperitoneally (i.p) 30 minutes before harvesting the flap tissue. In a separate group, SR144528 (a selective CB2 receptor inverse agonist) was injected before the most effective dose of sumatriptan to determine the possible involvement of CB2 receptors in its action. Histopathological examinations, the expression level of CB2 receptors (by western blot analysis), and IL-1 and TNF-α concentrations (ELISA) were explored in the skin flap samples. Results: Sumatriptan 0.3 mg/kg remarkably enhanced the skin flap survival in all macroscopic and microscopic investigations compared to the control group (P &lt;0.001). IL-1 and TNF-α levels were significantly attenuated (P &lt;0.001), and the expression of CB2 receptors in skin cells was amplified in rats treated with sumatriptan 0.3 mg/kg (p &lt;0.05) compared to the control group. However, the administration of SR144528 (2 mg/kg) nullified all the protective effects of sumatriptan (0.3 mg/kg). Conclusion: We discovered that CB2 receptors play a crucial role in the favorable effects of sumatriptan on skin flap survival as a novel mechanism of action. So, targeting these receptors seems to be a dependable method in skin flap surgeries to ensure its survival and prevent tissue necrosis. Further experimental and clinical investigations are needed to ensure the safe clinical application of this method.
DOI: 10.15482/usda.adc/1372907
title: Measured Annual Nutrient loads from AGricultural Environments (MANAGE) database
DOI: 10.6084/m9.figshare.28741742.v1
title: RC beam repair using conventional cementitious mortar

description: The raw experimental data supporting the findings of this study are available on Figshare, and the data are also available from the corresponding author upon reasonable request.
DOI: 10.6084/m9.figshare.15028926.v1
title: Supplementary Material for: Trends in Literature on Cerebral Bypass Surgery: A Systematic Review

description: <b><i>Introduction:</i></b> Ever since the beginning of cerebral bypass surgery, the role of the bypass has been debated and indications have changed over the last 5 decades. This systematic literature research analysed all clinical studies on cerebral bypass that have been published from January 1959 to January 2020 for their year of publication, country of origin, citation index, role of and indication for bypass, bypass technique, revascularized territory, flow capacity, and title (for word cloud analysis per decade). <b><i>Methods:</i></b> A systematic literature research was conducted using PubMed, Web of Science, EMBASE, and SCOPUS databases. All studies that have been published until January 1, 2020, were included. <b><i>Results:</i></b> Of 6,013 identified studies, 2,585 were included in the analysis. Of these, <i>n</i> = 1,734 (67%) studies addressed flow-augmentation bypass and <i>n</i> = 701 (27%) addressed flow-preservation bypass. The most common indication reported for flow augmentation is moyamoya (<i>n</i> = 877, 51%), followed by atherosclerotic steno-occlusive disease (<i>n</i> = 753, 43%). For flow preservation, the most common indication is studies reporting on cerebral aneurysm surgery (<i>n</i> = 659, 94%). The increasing popularity of reporting on these bypass operations almost came to an end with the FDA approval of flow diverters for aneurysm treatment in 2011. Japan is the country with the most bypass studies (cumulatively published 933 articles), followed by the USA (630 articles) and China (232 articles). <b><i>Discussion/Conclusion:</i></b> Clinical studies on cerebral bypass surgery have become increasingly popular in the past decades. Since the introduction of moyamoya as a distinct pathologic entity, Asian countries in particular have a very active community regarding this disease, with an increasing number of articles published every year. Studies on bypass for chronic steno-occlusive disease peaked in the 1980s but have remained the main focus of bypass research, particularly in many European departments. The number of reports published on these bypass operations significantly decreased after the FDA approval of flow diverters for aneurysm treatment in 2011.
DOI: 10.6084/m9.figshare.28832450.v1
title: complex optical constants as functions of wavelengths, of the thin film of $S_1$ and $S_4$ deposited on silicon, by spectroscopic ellipsometry.

description: We obtained complex optical constants, viz. refractive indices and extinction coefficients as a function of wavelengths, of the thin film of $S_1$ and $S_4$ deposited on silicon, by spectroscopic ellipsometry. These values are useful in obtaining steady-state and transient-state behavior for OLED devices in the OLED simulation suite SETFOS.<br>
DOI: 10.6084/m9.figshare.5129644.v1
title: Supplementary Material for: Ambulatory Activity Components Deteriorate Differently across Neurodegenerative Diseases: A Cross-Sectional Sensor-Based Study

description: <b><i>Background and Purpose:</i></b> Reduced ambulatory activity is a major burden in neurodegenerative disease (NDD), leading to severe restrictions in social participation and further deterioration of motor capacities. However, objective evidence on walking behavior patterns and components underlying this impairment and its decline with disease progression is scarce for many NDDs. We aimed to unravel the detailed metrics underlying the reduced ambulatory activity in selected NDDs, and their relation to disease duration. We hypothesized that progressively reduced ambulatory activity is a feature shared across different NDDs, characterized by changes in both common and distinct components. <b><i>Methods:</i></b> Sixty-five subjects with NDD (n = 34 degenerative ataxia; n = 15 progressive supranuclear palsy, and n = 16 Parkinson's disease) and 38 healthy older adults (total n = 103) wore a three-axial accelerometer (activPAL3™) for 7 consecutive days. Detailed metrics of ambulatory activity were calculated. <b><i>Results:</i></b> The average daily walking duration was significantly decreased in all three NDDs, yet characterized by a differential pattern of changes in number and length of walking bouts and sit-to-stand transfers. Decline in walking duration progressed with increased disease duration in all three NDDs, yet at a differing rate. This decline was associated with progressive reductions in walking bout length and walking behavior pattern diversity in all three NDDs. <b><i>Conclusions:</i></b> These findings provide objective evidence that reduced ambulatory activity is a shared feature across different NDDs. Moreover, they reveal that several underlying walking behavior components change with increasing disease duration, yet at a differing rate in different NDDs. This indicates that metric analysis of ambulatory activity might provide ecologically relevant and disease-specific progression and outcome markers in several NDDs.
DOI: 10.6084/m9.figshare.26495956.v3
title: NetGP

description: Some of the datasets and trained models used in NetGP.
DOI: 10.6084/m9.figshare.24634755.v3
title: Thermally Activated Delayed Fluorescence emitter

description: This is a Thermally Activated Delayed Fluorescence emitter containing more than 250 samples.We also added some donor and receptor molecular fragments.If you would like to use this dataset, please contact me. My email is gammanhang@gmail.com
DOI: 10.6084/m9.figshare.28523882.v1
title: <b>Unequal crossover and recombination at minimal repeat sequences are ubiquitous in primates and mouse reaching maximum magnitude in human</b>

description: We previously reported that minimal repeat sequences, such as AT/TA dinucleotide 2- and 3-repeat units (D2Us and D3Us, respectively) and trinucleotide two-repeat units (T2Us) are ubiquitous sites of unequal crossover and recombination, and consequent colonization across the human genome. These sites also underscored the preference of AT- over CG-rich sequences, as recombination sites. Whereas in several selected colonies of various sizes these events reached maximum complexity in human, the overall colonization pattern in species other than human remains uncertain.
DOI: 10.6084/m9.figshare.3840513.v1
title: Sampling Goldenrod plant population with transect, and trait sampling techniques

description: Methods: In order to familiarize with sampling techniques, and equipment, field training with Goldenrod population sampling was conducted on York University grasslands.50 Goldenrod samples were studied in a 30 m area along a randomly placed transect tape, within 50 cm radius from the tape.Distance of each sample from zero end of the tape was recorded, in addition to height of a plant measured from ground to the highest point of it, even if it was a leaf or flower not only stem. number of leaves from the bottom, and number of flowers were counted and recorded, excluding dry, brown leaves, and dead flowers, as well as bourgeons less than 1cm. Patch density was also assessed by counting other plants within 50cm radius in a scale as: 0 - open; 1 - 1 to 3 plants nearby; 2 - 4 to 6 plants nearby; 3 - 7 to 9 plants, 4 - very crowded patch with 10 and more plants nearby. excluding weeds and grass.<br><br>
DOI: 10.6084/m9.figshare.20473529.v1
title: Navigating the Space between Policy and Practice: Toward a Typology of Collaborators in a Federal Land Management Agency

description: Navigating the space between policy and on-the-ground natural resource management presents unique challenges. We interviewed 22 U.S. Bureau of Land Management Field Office Managers to understand their perceptions toward, and applications of, collaboration with public and private stakeholders. Interviews were transcribed and open-coded using qualitative data analysis software. Then, each interview was represented visually using the MaxQDA MaxMaps feature. We deductively coded each visual model and created a typology based on a mix of salient traits exhibited by each group. Differences emerged in each group’s approach to teaching and learning; communication style; attitude toward collaboration; attention to relational and substantive outcomes; and the ability to create space within the agency mission to achieve mutually beneficial goals. Findings can help agencies navigate the challenges associated with aligning agency directives with on-the-ground realities in different contexts when collaborators exhibit different traits.
DOI: 10.6084/m9.figshare.17158040.v1
title: Supplementary Material for: Effects of Weight Loss on Adipose and Muscular Neuropilin 1 mRNA Expression in Obesity: Potential Implication in SARS-CoV-2 Infections?

description: <b><i>Introduction:</i></b> Neuropilin 1 (NRP-1) is a novel co-receptor promoting SARS-CoV-2 infectivity. Animal data indicate a role in trans-endothelial lipid transport and storage. As human data are sparse, we aimed to assess the role of NRP-1 in 2 metabolic active tissues in human obesity and in the context of weight loss-induced short- and long-term metabolic changes. <b><i>Methods:</i></b> After a standardized 12-week weight reduction program, 143 subjects (age &gt;18; body mass index ≥27 kg/m<sup>2</sup>, 78% female) were randomized to a 12-month lifestyle intervention or a control group using a stratified randomization scheme. This was followed by 6-month follow-up without any intervention. Phenotyping was performed before and after weight loss, after 12-month intervention and after subsequent 6 months of follow-up. Tissue-specific insulin sensitivity was estimated by HOMA-IR (whole body and mostly driven by liver), insulin sensitivity index (ISI)<sub>Clamp</sub> (predominantly skeletal muscle), and free fatty acid (FFA) suppression during hyperinsulinemic-euglycemic clamp (FFA<sub>Supp</sub>) (predominantly adipose tissue). NRP-1 mRNA expression was measured in subcutaneous adipose tissue (NRP-1<sub>AT</sub>) and skeletal muscle (NRP-1<sub>SM</sub>) before and after weight loss. <b><i>Results:</i></b> NRP-1 was highly expressed in adipose tissue (7,893 [7,303–8,536] counts), but neither NRP-1<sub>AT</sub> nor NRP-1<sub>SM</sub> were related to estimates of obesity. Higher NRP-1<sub>AT</sub> was associated with stronger FFA<sub>Supp</sub> (<i>r</i> = −0.343, <i>p</i> = 0.003) and a tendency to higher ISI<sub>Clamp</sub> (<i>r</i> = 0.202, <i>p</i> = 0.085). Weight loss induced a decline of NRP-1<sub>AT</sub> but not NRP-1<sub>SM</sub>. This was more pronounced in subjects with stronger reduction of adipose ACE-2 mRNA expression (<i>r</i> = 0.250; <i>p</i> = 0.032) but was not associated with short- and long-term improvement of FFA<sub>Supp</sub> and ISI<sub>Clamp</sub>. <b><i>Conclusion:</i></b> NRP-1<sub>AT</sub> is related to adipose insulin sensitivity in obesity. Weight loss-induced decline of NRP-1<sub>AT</sub> seems not to be involved in metabolic short- and long-term improvements after weight loss. However, weight loss-induced reduction of both NRP-1<sub>AT</sub> and ACE-2<sub>AT</sub> indicates a lower susceptibility of adipose tissue for SARS-CoV-2 after body weight reduction.
DOI: 10.6084/m9.figshare.13322597.v1
title: Capital Metro Bus, Temperature, and Sociodemographic Data for Austin, Texas (2019)

description: Data were collected for a study, titled "Heat-moderating effects of bus stop shelters and tree shade on public transport ridership." In this study, authors determined whether bus stop shelters and tree canopy surrounding bus stops moderated the effect of warm season temperatures on ridership in Austin, Texas, and whether shelters and tree canopy were equitably distributed. Data are for 2,271 bus stops of Capital Metropolitan Transportation Authority, and span the 2019 warm season (April 1st through September 30th). Data are either at the bus stop level or day level. Data set includes all data used in the analysis. Please see associated metadata for description and source of each field. Contact Kevin Lanza (Kevin.L.Lanza@uth.tmc.edu) with any questions.
DOI: 10.6084/m9.figshare.11346650.v1
title: Supplementary Material for: Continuous Sound Collection Using Smartphones and Machine Learning to Measure Cough

description: <b><i>Background:</i></b> Despite the efforts of research groups to develop and implement at least partial automation, cough counting remains impractical. Analysis of 24-h cough frequency is an established regulatory endpoint which, if addressed in an automated manner, has the potential to ease cough symptom evaluation over multiple 24-h periods in a patient-centric way, supporting the development of novel treatments for chronic cough, an unmet clinical need. <b><i>Objectives:</i></b> In light of recent technological advancements, we propose a system based on the use of smartphones for objective continuous sound collection, suitable for automated cough detection and analysis. Two capabilities were identified as necessary for naturalistic cough assessment: (1) recording sound in a continuous manner (sound collection), and (2) detection of coughs from the recorded sound (cough detection). <b><i>Methods:</i></b> This work did not involve any human subject testing or trials. For sound collection, we designed, built, and verified technical parameters of a smartphone application for sound collection. Our cough detection work describes the development of a mathematical model for sound analysis and cough identification. Performance of the model was compared to previously published results of commercially available solutions and to human raters. The compared solutions use the following methods to automatically or semi-automatically assess cough: 24-h sound recording with an ambulatory device with multiple microphones, automatic silence removal, and manual recording review for cough count. <b><i>Results:</i></b> Sound collection: the application demonstrated the ability to continuously record sounds using the phone’s internal microphone; the technical verification informed the configuration of the technical and user experience parameters. Cough detection: our cough recognition sensitivity to cough as determined by human listeners was 90 at 99.5% specificity preset and 75 at 99.9% specificity preset for a dataset created from publicly available data. <b><i>Conclusions:</i></b> Sound collection: the application reliably collects sound data and uploads them securely to a remote server for subsequent analysis; the developed sound data collection application is a critical first step toward future incorporation in clinical trials. Cough detection: initial experiments with cough detection techniques yielded encouraging results for application to patient-collected data from future studies.
DOI: 10.6084/m9.figshare.28020500.v1
title: 0.74 ng

description: This dataset was used to explore deep learning models ability to quantify analyte load of LFA. Commercially available COVID-19 Rapid test kits, which test for the presence of nucleocapsid(N) protein, were photographed with a smartphone after results were ready. During the testing a known amount of N protein was added to the extraction buffer tube after which the following steps were performed according to manufacturer's instructions. This dataset was used to train deep learning models to classify various levels of N protein.
DOI: 10.6084/m9.figshare.977874.v1
title: Hierarchical modelling of population growth rate from individual capture-recapture data

description: Input data for the BUGS model in Appendix S1, and related ReadMe file. Aritcle: S. Tenan, R. Pradel, G. Tavecchia, J. M. Igual, A. Sanz-Aguilar, M. Genovart, D. Oro (2014) Hierarchical modelling of population growth rate from individual capture-recapture data. Methods in Ecology and Evolution.
DOI: 10.6084/m9.figshare.19733347.v1
title: Gene expression data in gastric cancer

description: In this research, we identified a small set of genes that could be used to distinguish gastric cancer from normal tissues, by performing filter feature selection algorithms
DOI: 10.4121/13109561.v1
title: Data presented in the paper: Does plastic waste kill mangroves? - A field experiment to assess the impact of macro plastics on mangrove growth, stress response and survival.

description: The aim of this dataset was to investigate how plastic waste on the forest floor and in mangrove sediment might affect mangrove trees. We first assessed the size of the current plastic waste problem in mangroves by quantifying the relatively mobile plastic fraction on the forest floor (the percentage of the forest floor covered by plastic, and the number of plastic items per square meter), and by quantifying the more immobile plastic fraction buried in the rhizospheric sediment of eight coastal mangrove fringes (plastic monitoring dataset). We subsequently investigated the effects of a range of plastic cover percentages (0%, 50% and 100%) on root growth, stress response of the tree, and tree survival of 42 mangrove trees in the field over a period of six weeks (plastic suffocation experiment dataset).
DOI: 10.6084/m9.figshare.13396091.v1
title: Supplementary Material for: γ-Secretase Genetics of Hidradenitis Suppurativa: A Systematic Literature Review

description: <b><i>Background:</i></b> Acne inversa/hidradenitis suppurativa (HS) is a chronic, recurrent inflammatory disease of the skin that can significantly affect patients’ quality of life. The etiology and pathogenesis of HS are unclear and gene mutations might play a role. <b><i>Summary:</i></b> The primary focus of the review is on aggregating the gene mutations reported, summarizing the structure of γ-secretase and analyzing and speculating about the mechanism and the underlying relations between gene mutation and functional changes of protein. The systematic literature review was done by searching the PubMed, Embase, and Web of Science databases. γ-Secretase is an intramembrane protease complex responsible for the intramembranous cleavage of more than 30 type-1 transmembrane proteins including amyloid precursor protein and Notch receptors. The protein complex consists of four hydrophobic proteins: presenilin, presenilin enhancer-2 (PSENEN), nicastrin, and anterior pharynx defective 1 (APH1). To date, 57 mutations of γ-secretase genes have been reported in 70 patients or families worldwide, including 39 in NCSTN, 14 in PSENEN, and 4 in PSEN1, of which 17 are frameshifts, 15 result in nonsense mutations, 13 in missense mutations, and 12 are splice site mutations. Given the structure of γ-secretase and analysis of related mutation loci of NCSTN, PSENEN, and PSEN1, mutations in γ-secretase genes could affect activation of presenilin, prevent substrate binding, and hinder intramembrane cleavage of select proteins.
DOI: 10.6084/m9.figshare.13204856.v1
title: Simulated signal properties for axion minicluster-neutron star encounters

description: Simulated radio signals from encounters between QCD axion miniclusters (AMCs) and neutron stars in the Milky Way.<br>Each file contains a sample of 10^7 signals. The different columns are: Distance from Earth [pc], Galactic Longitude [deg], Galactic Latitude [deg], Length of encounter [s], Mean Flux [muJy], MC density [Msun/pc^3], MC radius [pc].<br>The file labels "PL" and "NFW" denote the internal density profiles of the AMCs. Files labeled with "unperturbed" neglect the effects of stellar perturbations on the AMC propulation and files labeled with "AScut" include a cut on low-mass AMCs to eliminate problematic AMCs which may be dominated by an axion star (AS). <br>For more details, see the associated paper "Transient Radio Signatures from Neutron Star Encounters with QCD Axion Miniclusters" (Edwards, Kavanagh, Visinelli & Weniger, 2020).
DOI: 10.21227/0da4-g645
title: "RealAIGI: Realistic AI Generated Image Dataset"

description: "The rapid advancement of generative neural networks has facilitated the creation of photorealistic images, raising concerns about the proliferation of misinformation. Detecting AI-generated fakes has become crucial, given their potential impact on public opinion and various sectors. This paper presents a comparative analysis of real and AI-generated images, focusing on building a novel dataset named Realistic AI-Generated Image (RealAIGI) dataset. Leveraging sophisticated diffusion transformer models like Sora, the dataset comprises diverse general content, aiming to match the scale of existing general image datasets. We discuss the significance of such datasets in enhancing detection systems' robustness and real-world applicability, this work contributes to advancing AI-generated image detection."
DOI: 10.6084/m9.figshare.5959927.v1
title: Array Associations

description: We have also tested whether any of the six reported SNPs available in UK Biobank had different MAFs in the UK BiLEVE and UK Biobank samples (suggestive of a chip effect); however none showed evidence of this.
DOI: 10.6084/m9.figshare.24541366.v6
title: Proteomic and Metabolomic Analyses of Blood Samples of Highly Trained Athletes

description: Proteomic and Metabolomic Analyses of Blood Samples of Highly Trained Athletes
DOI: 10.6084/m9.figshare.28548725.v1
title: Magnificent Seven

description: zipped data to be downloaded by students.