cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q2m61n5r
title: BindingDB Entry 50047604: Discovery of novel 7-azaindoles as PDK1 inhibitors.

description: Small molecule binding data for protein 3-phosphoinositide dependent protein kinase-1, PI3-kinase subunit alpha, PI3-kinase subunit beta, PI3-kinase subunit delta, and PI3-kinase subunit gamma, Uniprot O00329, O15530, P42336, P42338, and P48736
DOI: 10.7270/q2qz2cwr
title: BindingDB Entry 50047603: Tasiamide F, a potent inhibitor of cathepsins D and E from a marine cyanobacterium.

description: Small molecule binding data for protein Beta-secretase 1, Cathepsin D, and Cathepsin E, Uniprot P07339, P14091, and P56817
DOI: 10.7270/q2vq34mg
title: BindingDB Entry 50047602: Allosteric Glutaminase Inhibitors Based on a 1,4-Di(5-amino-1,3,4-thiadiazol-2-yl)butane Scaffold.

description: Small molecule binding data for protein Glutaminase kidney isoform, mitochondrial, Uniprot O94925
DOI: 10.7270/q2028tdn
title: BindingDB Entry 50047087: Application of PEG-400 as a green biodegradable polymeric medium for the catalyst-free synthesis of spiro-dihydropyridines and their use as acetyl and butyrylcholinesterase inhibitors.

description: Small molecule binding data for protein Acetylcholinesterase and Cholinesterase, Uniprot P06276 and P22303
DOI: 10.7270/q27083bj
title: BindingDB Entry 50047607: GSK114: A selective inhibitor for elucidating the biological role of TNNI3K.

description: Small molecule binding data for protein RAF serine/threonine protein kinase and TNNI3K, Uniprot P15056 and Q59H18
DOI: 10.7270/q2bp04qp
title: BindingDB Entry 50047606: Coumarin carboxylic acids as monocarboxylate transporter 1 inhibitors: In vitro and in vivo studies as potential anticancer agents.

description: Small molecule binding data for protein Monocarboxylate transporter 1 (MCT1), Uniprot P53987
DOI: 10.7270/q2cz395s
title: BindingDB Entry 50048133: Targeting the Inhibition of Tryptophan 2,3-Dioxygenase (TDO-2) for Cancer Treatment.

description: Small molecule binding data for protein Tryptophan 2,3-dioxygenase, Uniprot P48775
DOI: 10.7270/q2gf0wdk
title: BindingDB Entry 50047605: Novel approaches to map small molecule-target interactions.

description: Small molecule binding data for protein Bile acid receptor FXR, Uniprot Q96RI1
DOI: 10.7270/q2hq41w3
title: BindingDB Entry 50048132: Potential of Renal Outer Medullary Potassium (ROMK) Channel as Treatments for Hypertension and Heart Failure.

description: Small molecule binding data for protein ATP-sensitive inward rectifier potassium channel 1, Uniprot P48048
DOI: 10.7270/q2ks6tcz
title: BindingDB Entry 50047090: Design, synthesis, and docking studies of afatinib analogs bearing cinnamamide moiety as potent EGFR inhibitors.

description: Small molecule binding data for protein Epidermal growth factor receptor and Vascular endothelial growth factor receptor 2, Uniprot P00533 and P35968
DOI: 10.7270/q2nc636h
title: BindingDB Entry 50048131: Synthesis and application ofß-carbolines as novel multi-functional anti-Alzheimer's disease agents.

description: Small molecule binding data for protein Cholinesterase, Uniprot P06276
DOI: 10.7270/q2qj7k44
title: BindingDB Entry 50047089: A potent and selective inhibitor targeting human and murine 12/15-LOX.

description: Small molecule binding data for protein 12-Lipoxygenase (12-LOX), 15-Lipoxygenase-2 (15-LOX-2), 5-lipoxygenase/FLAP, Arachidonate 15-lipoxygenase, and Cyclooxygenase, Uniprot O15296, P09917, P16050, P18054, and P35354
DOI: 10.7270/q2s46tzw
title: BindingDB Entry 50048130: Novel 3-methylindoline inhibitors of EZH2: Design, synthesis and SAR.

description: Small molecule binding data for protein Enhancer of zeste homolog 1 (EZH1) and Histone-lysine N-methyltransferase EZH2, Uniprot Q15910 and Q92800
DOI: 10.7270/q2v989xb
title: BindingDB Entry 50047088: Design, synthesis and biological evaluation of novel 4-phenoxy-6,7-disubstituted quinolines possessing (thio)semicarbazones as c-Met kinase inhibitors.

description: Small molecule binding data for protein Epidermal growth factor receptor, Hepatocyte growth factor receptor, Macrophage-stimulating protein receptor, Platelet-derived growth factor receptor, Tyrosine-protein kinase Kit (Kit), Tyrosine-protein kinase receptor FLT3, and Vascular endothelial growth factor receptor 2, Uniprot P00533, P08581, P10721, P16234, P35968, P36888, and Q04912
DOI: 10.7270/q2ww7knv
title: BindingDB Entry 50048129: Discovery of a new isomannide-based peptidomimetic synthetized by Ugi multicomponent reaction as human tissue kallikrein 1 inhibitor.

description: Small molecule binding data for protein Kallikrein 1 and Kallikrein 7, Uniprot P06870 and P49862
DOI: 10.7270/q20p120q
title: BindingDB Entry 50048136: Design and Synthesis of Novel Meta-Linked Phenylglycine Macrocyclic FVIIa Inhibitors.

description: Small molecule binding data for protein Coagulation factor III/Factor VIIa (fVIIa), Kallikrein 1, and Vitamin K-dependent protein C, Uniprot P04070, P06870, P08709, and P13726
DOI: 10.7270/q22v2j07
title: BindingDB Entry 50047094: Synthesis and evaluation of analogs of the phenylpyridazinone NPD-001 as potent trypanosomal TbrPDEB1 phosphodiesterase inhibitors and in vitro trypanocidals.

description: Small molecule binding data for protein Class I phosphodiesterase B1 (TbrPDEB1), Phosphodiesterase 11A (PDE11A), Phosphodiesterase 7, Phosphodiesterase 8, Phosphodiesterase 9A, Phosphodiesterase, PDE1/PDE5, cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B, cAMP-specific 3',5'-cyclic phosphodiesterase 4D, cGMP-dependent 3',5'-cyclic phosphodiesterase, and cGMP-specific 3',5'-cyclic phosphodiesterase, Uniprot O00408, O76074, O76083, O95263, Q01064, Q07343, Q08499, Q13946, Q9HCR9, and Q9Y233
DOI: 10.7270/q2377bn8
title: BindingDB Entry 50047608: Development of hydroxy-based sphingosine kinase inhibitors and anti-inflammation in dextran sodium sulfate induced colitis in mice.

description: Small molecule binding data for protein Sphingosine kinase 1 (SPHK1) and Sphingosine kinase types 2 (SphK2), Uniprot Q9NRA0 and Q9NYA1
DOI: 10.7270/q24f1sqn
title: BindingDB Entry 50048135: 2-Hydroxypyridine-

description: Small molecule binding data for protein Tyrosinase, Uniprot P14679
DOI: 10.7270/q26m38p3
title: BindingDB Entry 50047093: Structure-guided design of new indoles as negative allosteric modulators (NAMs) of N-methyl-D-aspartate receptor (NMDAR) containing GluN2B subunit.

description: Small molecule binding data for protein N-methyl D-aspartate receptor subtype 2B (NMDA)(NR2B), Uniprot Q00960
DOI: 10.7270/q2862jfc
title: BindingDB Entry 50048134: Investigation of a Bicyclo[1.1.1]pentane as a Phenyl Replacement within an LpPLA

description: Small molecule binding data for protein LDL-associated phospholipase A2, Uniprot Q13093
DOI: 10.7270/q2b85b0h
title: BindingDB Entry 50047092: Design and synthesis of a new generation of substituted purine hydroxamate analogs as histone deacetylase inhibitors.

description: Small molecule binding data for protein HDACs, Histone deacetylase, and Histone deacetylase 8, Uniprot Q13547, Q92769, and Q9BY41
DOI: 10.7270/q2ff3v9n
title: BindingDB Entry 50047613: Identification of potent and selective retinoic acid receptor gamma (RAR¿) antagonists for the treatment of osteoarthritis pain using structure based drug design.

description: Small molecule binding data for protein Retinoic acid receptor alpha/Retinoid X receptor alpha, Uniprot P10276 and P19793
DOI: 10.7270/q2g162pc
title: BindingDB Entry 50047091: Synthesis and biological evaluation of new fluorinated and chlorinated indenoisoquinoline topoisomerase I poisons.

description: Small molecule binding data for protein Tyrosyl-DNA phosphodiesterase 1 (TDP1) and tyrosyl-DNA phosphodiesterase 2, Uniprot O95551 and Q9NUW8
DOI: 10.7270/q2k64m0x
title: BindingDB Entry 50047612: Novel JAK1-selective benzimidazole inhibitors with enhanced membrane permeability.

description: Small molecule binding data for protein JAK2/TYK2, JAK3/JAK1, Tyrosine-protein kinase JAK1, and Tyrosine-protein kinase JAK2, Uniprot O60674, P23458, P29597, P52332, and P52333
DOI: 10.7270/q2mg7rhh
title: BindingDB Entry 50048139: Structural Basis for the Effective Myostatin Inhibition of the Mouse Myostatin Prodomain-Derived Minimum Peptide.

description: Small molecule binding data for protein Growth/differentiation factor 8, Uniprot O14793
DOI: 10.7270/q2pz5bqx
title: BindingDB Entry 50047611: Discovery of indole inhibitors of chemokine receptor 9 (CCR9).

description: Small molecule binding data for protein C-C chemokine receptor type 9, Uniprot P51686
DOI: 10.7270/q2tb18r2
title: BindingDB Entry 50047096: Discovery of high affinity inhibitors of Leishmania donovani N-myristoyltransferase.

description: Small molecule binding data for protein Peptide N-myristoyltransferase, Uniprot P30419
DOI: 10.7270/q2tq63fn
title: BindingDB Entry 50047610: Discovery of hydroxyl 1,2-diphenylethanamine analogs as potent cholesterol ester transfer protein inhibitors.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2 and Cholesteryl ester transfer protein, Uniprot P11597 and P40989
DOI: 10.7270/q2z321h7
title: BindingDB Entry 50047095: Synthesis, biological evaluation and structural analysis of novel peripherally active morphiceptin analogs.

description: Small molecule binding data for protein Delta-type opioid receptor, Kappa-type opioid receptor, Mu-type opioid receptor, Nociceptin/mu opioid receptor, Opioid receptors; mu & delta, and mu/kappa opioid receptor, Uniprot P33533, P33535, P35372, P41143, P41144, and P41145
DOI: 10.7270/q2zg6v50
title: BindingDB Entry 50047609: Synthesis and biological activity of pyrazole analogues of the staurosporine aglycon K252c.

description: Small molecule binding data for protein Serine/threonine-protein kinase PIM, Uniprot P11309, Q86V86, and Q9P1W9
DOI: 10.7270/q21v5gvf
title: BindingDB Entry 50047102: New Synthetic Routes to Triazolo-benzodiazepine Analogues: Expanding the Scope of the Bump-and-Hole Approach for Selective Bromo and Extra-Terminal (BET) Bromodomain Inhibition.

description: Small molecule binding data for protein Bromodomain-containing protein 2 and Bromodomain-containing protein 4, Uniprot O60885 and P25440
DOI: 10.7270/q22809hf
title: BindingDB Entry 50047616: Discovery of selective inhibitors of tyrosyl-DNA phosphodiesterase 2 by targeting the enzyme DNA-binding cleft.

description: Small molecule binding data for protein Tyrosyl-DNA phosphodiesterase 1, Tyrosyl-DNA phosphodiesterase 2, and Tyrosyl-DNA phosphodiesterase 2 (mTDP2 WT), Uniprot O95551, Q1LU95 Q4V912 A0SKZ8 Q1LWU3 Q5XJA0 A4FUK7, Q9JJX7, and Q9NUW8
DOI: 10.7270/q25m67mm
title: BindingDB Entry 50047101: Discovery of Molecular Therapeutics for Glaucoma: Challenges, Successes, and Promising Directions.

description: Small molecule binding data for protein Adenosine receptor A1, Adenosine receptor A2a, Adenosine receptor A2b, Adenosine receptor A3, Rho-associated protein kinase, and Transmembrane domain-containing protein TMIGD3, Uniprot O75116, P0DMS8, P0DMS9, P25099, P29274, P29275, P30542, and Q13464
DOI: 10.7270/q2611275
title: BindingDB Entry 50047615: Structure-activity relationships of dibenzoylhydrazines for the inhibition of P-glycoprotein-mediated quinidine transport.

description: Small molecule binding data for protein P-glycoprotein 1, Uniprot P08183
DOI: 10.7270/q2765hbf
title: BindingDB Entry 50048142: Development of 4-Heteroarylamino-1'-azaspiro[oxazole-5,3'-bicyclo[2.2.2]octanes] asa7 Nicotinic Receptor Agonists.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2, Neuronal acetylcholine receptor protein alpha-7 subunit, and Serotonin 3 (5-HT3) receptor, Uniprot P36544, P40989, and P46098
DOI: 10.7270/q29c709w
title: BindingDB Entry 50047100: Orexin Receptor Antagonists: New Therapeutic Agents for the Treatment of Insomnia.

description: Small molecule binding data for protein Cytochrome P450 3A, Orexin receptor 1, and Orexin receptor 2, Uniprot O43613, O43614, P08684, and S4X0W3
DOI: 10.7270/q29s1sxb
title: BindingDB Entry 50047614: New halogenated tris-(phenylalkyl)amines as h5-HT2B receptor ligands.

description: Small molecule binding data for protein 5-Hydroxytryptamine receptor 2A (5-HT2A), 5-Hydroxytryptamine receptor 2C (5-HT2C), and Serotonin receptor (2b and 2c), Uniprot P28223, P28335, and P41595
DOI: 10.7270/q2bz682v
title: BindingDB Entry 50048141: Discovery of Spirocyclic Aldosterone Synthase Inhibitors as Potential Treatments for Resistant Hypertension.

description: Small molecule binding data for protein Cytochrome P450 11B2 and Steroid 11-beta-Hydroxylase (CYP11B1), Uniprot P15538 and P19099
DOI: 10.7270/q2f47r0s
title: BindingDB Entry 50047099: Fragment-Based Design of Selective Nanomolar Ligands of the CREBBP Bromodomain.

description: Small molecule binding data for protein Bromodomain-containing protein 2, Bromodomain-containing protein 4, and CREB-binding protein/p53, Uniprot O60885, P25440, and Q92793
DOI: 10.7270/q2gq70s5
title: BindingDB Entry 50048140: Systematic Study of Effects of Structural Modifications on the Aqueous Solubility of Drug-like Molecules.

description: Small molecule binding data for protein Macrophage migration inhibitory factor (MIF), Uniprot P14174
DOI: 10.7270/q2js9s9g
title: BindingDB Entry 50047098: Discovery of a Chemical Tool Inhibitor Targeting the Bromodomains of TRIM24 and BRPF.

description: Small molecule binding data for protein Bromodomain and PHD finger-containing protein 3, Bromodomain-containing protein 1, Peregrin, and Transcription intermediary factor 1-alpha, Uniprot O15164, O95696, P55201, and Q9ULD4
DOI: 10.7270/q2nz89j3
title: BindingDB Entry 50047619: A combined ligand- and structure-based approach for the identification of rilmenidine-derived compounds which synergize the antitumor effects of doxorubicin.

description: Small molecule binding data for protein Alpha-2A adrenergic receptor and Imidazoline I1, Uniprot P08913 and Q4G017
DOI: 10.7270/q2pk0j09
title: BindingDB Entry 50047097: Discovery and Characterization of GSK2801, a Selective Chemical Probe for the Bromodomains BAZ2A and BAZ2B.

description: Small molecule binding data for protein Bromodomain adjacent to zinc finger domain protein 2A, Bromodomain adjacent to zinc finger domain protein 2B, Bromodomain-containing protein 4, Bromodomain-containing protein 9, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2, isoform CRA_a, Transcription activator BRG1, and Transcription initiation factor TFIID subunit 1-like, Uniprot O60885, P51531, P51532, Q8IZX4, Q9H8M2, Q9UIF8, and Q9UIF9
DOI: 10.7270/q2r78h6s
title: BindingDB Entry 50048138: Discovery of Novel Seven-Membered Prostacyclin Analogues as Potent and Selective Prostaglandin FP and EP3 Dual Agonists.

description: Small molecule binding data for protein Prostaglandin E2 receptor, Prostaglandin E2 receptor EP2 subtype (EP2), Prostaglandin E2 receptor EP4 subtype (EP4), Prostanoid FP receptor, and Prostanoid IP receptor, Uniprot P35408, P43088, P43115, P43116, and P43119
DOI: 10.7270/q2sq928t
title: BindingDB Entry 50047618: Thiazolo[3,2-a]benzimidazol-3(2H)-one derivatives: Structure-activity relationships of selective nucleotide pyrophosphatase/phosphodiesterase1 (NPP1) inhibitors.

description: Small molecule binding data for protein Ectonucleotide pyrophosphatase/phosphodiesterase family member 1, Uniprot P22413
DOI: 10.7270/q2vx0jh1
title: BindingDB Entry 50048137: GluN2A-Selective Pyridopyrimidinone Series of NMDAR Positive Allosteric Modulators with an Improved

description: Small molecule binding data for protein Glutamate [NMDA] receptor subunit epsilon 1/zeta 1, Glutamate receptor AMPA 2/3, Ionotropic glutamate receptor NMDA 1/2C, and Ionotropic glutamate receptor NMDA 1/2D, Uniprot O15399, P42262, Q05586, Q12879, and Q14957
DOI: 10.7270/q23f4rn5
title: BindingDB Entry 50048143: Rational design, synthesis, and structure-activity relationships of 5-amino-1H-pyrazole-4-carboxylic acid derivatives as protein tyrosine phosphatase 1B inhibitors.

description: Small molecule binding data for protein Protein-tyrosine phosphatase 1B, Uniprot P18031
DOI: 10.7270/q28s4rvv
title: BindingDB Entry 50047622: Toward discovery of mutant EGFR inhibitors; Design, synthesis and in vitro biological evaluation of potent 4-arylamino-6-ureido and thioureido-quinazoline derivatives.

description: Small molecule binding data for protein Epidermal growth factor receptor and Epidermal growth factor receptor and ErbB2 (HER1 and HER2), Uniprot P00533, P04626, P21860, and Q15303
DOI: 10.7270/q2dj5hj4
title: BindingDB Entry 50047621: Discovery of a 2-hydroxyacetophenone derivative as an outstanding linker to enhance potency andß-selectivity of liver X receptor agonist.

description: Small molecule binding data for protein Liver X receptor (LXR alpha AND LXR beta), Uniprot P55055 and Q13133
DOI: 10.7270/q2fq9zmz
title: BindingDB Entry 50048148: Novel bis-arylalkylamines as myeloperoxidase inhibitors: Design, synthesis, and structure-activity relationship study.

description: Small molecule binding data for protein Myeloperoxidase (MPO) and Serotonin and norepinephrine transporters (SERT/NET), Uniprot P05164 and P31645
DOI: 10.7270/q2j67jv4
title: BindingDB Entry 50047620: Bacterial Peptide deformylase inhibition of cyano substituted biaryl analogs: Synthesis, in vitro biological evaluation, molecular docking study and in silico ADME prediction.

description: Small molecule binding data for protein Peptide deformylase
DOI: 10.7270/q2kh0qb7
title: BindingDB Entry 50048147: Design and synthesis of 1,2,3-triazole-containing N-acyl zanamivir analogs as potent neuraminidase inhibitors.

description: Small molecule binding data for protein Neuraminidase, Uniprot P03470
DOI: 10.7270/q2nk3gxd
title: BindingDB Entry 50047105: SAR Studies of 5-Aminopyrazole-4-carboxamide Analogues as Potent and Selective Inhibitors of Toxoplasma gondii CDPK1.

description: Small molecule binding data for protein Calmodulin-domain protein kinase 1 and VEGF-receptor 2 and tyrosine-protein kinase SRC, Uniprot P12931
DOI: 10.7270/q2q81g2z
title: BindingDB Entry 50048146: The therapeutic journey of pyridazinone.

description: Small molecule binding data for protein Prostanoid IP receptor, Uniprot P43119
DOI: 10.7270/q2sb47mp
title: BindingDB Entry 50047104: Design and Synthesis of Simplified Largazole Analogues as Isoform-Selective Human Lysine Deacetylase Inhibitors.

description: Small molecule binding data for protein Histone deacetylase, Histone deacetylase 1, Histone deacetylase 3/Nuclear receptor corepressor 2, and Histone deacetylase 8, Uniprot A0A024QZ26, O15379, Q13547, Q9BY41, Q9UBN7, and Q9Y618
DOI: 10.7270/q2v126s8
title: BindingDB Entry 50048145: Design of a novel thiophene inhibitor of 15-lipoxygenase-1 with both anti-inflammatory and neuroprotective properties.

description: Small molecule binding data for protein Arachidonate 15-lipoxygenase, Uniprot P16050
DOI: 10.7270/q2x350bd
title: BindingDB Entry 50047103: Synthesis and Biological Investigation of Oxazole Hydroxamates as Highly Selective Histone Deacetylase 6 (HDAC6) Inhibitors.

description: Small molecule binding data for protein Histone deacetylase, Histone deacetylase 1, and Histone deacetylase 8, Uniprot A0A024QZ26, Q13547, Q9BY41, and Q9UBN7
DOI: 10.7270/q2xg9t1m
title: BindingDB Entry 50047617: Aryl morpholino triazenes inhibit cytochrome P450 1A1 and 1B1.

description: Small molecule binding data for protein Cytochrome P450 1A1 and Cytochrome P450 1B1, Uniprot P04798 and Q16678
DOI: 10.7270/q2zp484t
title: BindingDB Entry 50048144: Novel pyrazolo[3,4-d]pyrimidines as dual Src-Abl inhibitors active against mutant form of Abl and the leukemia K-562 cell line.

description: Small molecule binding data for protein Tyrosine-protein kinase ABL1 and VEGF-receptor 2 and tyrosine-protein kinase SRC, Uniprot P00519 and P12931
DOI: 10.7270/q20v8fn5
title: BindingDB Entry 50047110: Rapid Synthesis of Boc-2',6'-dimethyl-l-tyrosine and Derivatives and Incorporation into Opioid Peptidomimetics.

description: Small molecule binding data for protein Kappa-type opioid receptor, Nociceptin/mu opioid receptor, and Opioid receptors; mu & delta, Uniprot P33533, P33535, and P41145
DOI: 10.7270/q21838fz
title: BindingDB Entry 50047624: Discovery of anti-cancer activity for benzo[1,2,4]triazin-7-ones: Very strong correlation to pleurotin and thioredoxin reductase inhibition.

description: Small molecule binding data for protein Thioredoxin reductase 3, Uniprot Q86VQ6
DOI: 10.7270/q22f7qfw
title: BindingDB Entry 50048151: Identification of acylthiourea derivatives as potent Plk1 PBD inhibitors.

description: Small molecule binding data for protein Serine/threonine-protein kinase PLK1, Uniprot P53350
DOI: 10.7270/q24m96db
title: BindingDB Entry 50047109: Inhibitors of the Antiapoptotic Myeloid Cell Leukemia-1 (Mcl-1) May Provide Effective Treatment for Cancer.

description: Small molecule binding data for protein Induced myeloid leukemia cell differentiation protein Mcl-1, Uniprot Q07820
DOI: 10.7270/q251415p
title: BindingDB Entry 50047623: Discovery of 3-benzyl-1,3-benzoxazine-2,4-dione analogues as allosteric mitogen-activated kinase kinase (MEK) inhibitors and anti-enterovirus 71 (EV71) agents.

description: Small molecule binding data for protein RAF serine/threonine protein kinase, Uniprot P15056
DOI: 10.7270/q2668g5m
title: BindingDB Entry 50048150: Discovery of novel inhibitors of Aurora kinases with indazole scaffold: In silico fragment-based and knowledge-based drug design.

description: Small molecule binding data for protein Aurora kinase A/B, Aurora kinase A/Targeting protein for Xklp2, Focal adhesion kinase 1/vascular endothelial growth factor receptor 3, Serine/threonine-protein kinase Aurora-C, Vascular endothelial growth factor receptor, and Vascular endothelial growth factor receptor 2, Uniprot L7RSL3, O14965, P17948, P35916, P35968, Q96GD4, and Q9UQB9
DOI: 10.7270/q28c9z4p
title: BindingDB Entry 50047108: Further Advances in Optimizing (2-Phenylcyclopropyl)methylamines as Novel Serotonin 2C Agonists: Effects on Hyperlocomotion, Prepulse Inhibition, and Cognition Models.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2, 5-Hydroxytryptamine receptor 2A (5-HT2A), 5-Hydroxytryptamine receptor 2C (5-HT2C), 5-Hydroxytryptamine receptor 6 (5-HT6), 5-Hydroxytryptamine receptor 7 (5-HT7), 5-hydroxytryptamine receptor 1A, Alpha-2A adrenergic receptor, Alpha-2B adrenergic receptor, Alpha-2C adrenergic receptor, Beta-2 adrenergic receptor and beta-3 adrenergic receptor, Dopamine receptor, Dopamine receptor D2L/neurotensin receptor NTS1, Dopamine receptors; D2 & D4, Histamine H2 receptor, Muscarinic acetylcholine receptor M1/M5 chimeric protein, Serotonin and norepinephrine transporters (SERT/NET), and Serotonin receptor (2b and 2c), Uniprot P07550, P08908, P08912, P08913, P14416, P18089, P18825, P21917, P25021, P28223, P28335, P31645, P34969, P35462, P40989, P41595, P50406, and Q4W594
DOI: 10.7270/q29z96wm
title: BindingDB Entry 50048149: Systemic optimization and structural evaluation of quinoline derivatives as transthyretin amyloidogenesis inhibitors.

description: Small molecule binding data for protein Transthyretin (TTR), Uniprot P02766
DOI: 10.7270/q2d50pt3
title: BindingDB Entry 50047107: Structure-Based Discovery of Novel and Selective 5-Hydroxytryptamine 2B Receptor Antagonists for the Treatment of Irritable Bowel Syndrome.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2, 5-Hydroxytryptamine receptor 2A (5-HT2A), 5-Hydroxytryptamine receptor 2C (5-HT2C), 5-Hydroxytryptamine receptor 6 (5-HT6), 5-Hydroxytryptamine receptor 7 (5-HT7), 5-hydroxytryptamine receptor 1A, 5-hydroxytryptamine receptor 1B, 5-hydroxytryptamine receptor 1D, Serotonin (5-HT) receptor, Serotonin 3 (5-HT3) receptor, and Serotonin receptor (2b and 2c), Uniprot P08908, P28221, P28222, P28223, P28335, P28566, P34969, P40989, P41595, P46098, P47898, and P50406