cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.15156/bio/sh0933038.10fu
title: SH0933038.10FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15156/bio/sh0933039.10fu
title: SH0933039.10FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15156/bio/sh0933040.10fu
title: SH0933040.10FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15468/dl.wzfeex
title: Occurrence Download

description: A dataset containing 65867 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Rana dalmatina Fitzinger, 1838",
 "HasCoordinate is true",
 "Year is greater than or equal to 2011",
 "Year is less than or equal to 2024"
 ]
}

 The dataset includes 65867 records from 1732 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0099597-240626123714530/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.7270/q23r0s6b
title: BindingDB Entry 50012420: Development of a phosphatase-stable phosphotyrosyl mimetic suitably protected for the synthesis of high-affinity Grb2 SH2 domain-binding ligands.

description: Small molecule binding data for protein Growth factor receptor-bound protein 2, Uniprot P62993
DOI: 10.7270/q24m9404
title: BindingDB Entry 50014409: Structure based design of a series of potent and selective non peptidic PTP-1B inhibitors.

description: Small molecule binding data for protein Protein-tyrosine phosphatase 1B, T-cell protein-tyrosine phosphatase, and Tyrosine-Protein Phosphatase (CD45), Uniprot P08575, P17706, and P18031
DOI: 10.7270/q26t0m7b
title: BindingDB Entry 50017845: Novel bis(1H-indol-2-yl)methanones as potent inhibitors of FLT3 and platelet-derived growth factor receptor tyrosine kinase.

description: Small molecule binding data for protein Breakpoint cluster region protein /Tyrosine-protein kinase ABL, PDGFR-beta/Platelet-derived growth factor receptor alpha, Platelet-derived growth factor receptor beta, Tyrosine-protein kinase ABL1, Tyrosine-protein kinase Kit (Kit), and Tyrosine-protein kinase receptor FLT3, Uniprot P00519, P05622, P09619, P10721, P11274, P26618, and P36888
DOI: 10.7270/q27080xx
title: BindingDB Entry 50016049: Sulfur-substituted alpha-alkyl phenethylamines as selective and reversible MAO-A inhibitors: biological activities, CoMFA analysis, and active site modeling.

description: Small molecule binding data for protein Monoamine oxidase, Uniprot P21396
DOI: 10.7270/q27h1hxn
title: BindingDB Entry 50012416: Isomeric acetoxy analogues of rofecoxib: a novel class of highly potent and selective cyclooxygenase-2 inhibitors.

description: Small molecule binding data for protein Cyclooxygenase and Cyclooxygenase-1 (COX-1), Uniprot P23219 and P35354
DOI: 10.7270/q28c9vpm
title: BindingDB Entry 50014408: The development of potent non-peptidic PTP-1B inhibitors.

description: Small molecule binding data for protein Protein-tyrosine phosphatase 1B and Tyrosine-Protein Phosphatase (CD45), Uniprot P08575 and P18031
DOI: 10.7270/q29k49t8
title: BindingDB Entry 50017871: Design, synthesis, and SAR studies of novel and highly active tri-cyclic HIV integrase inhibitors.

description: Small molecule binding data for protein Human immunodeficiency virus type 1 integrase
DOI: 10.7270/q2br8rpd
title: BindingDB Entry 50016045: 9-hydroxyazafluorenes and their use in thrombin inhibitors.

description: Small molecule binding data for protein Kallikrein-1 (KLK1), Plasminogen, Prothrombin, Tissue-type plasminogen activator, Trypsin-1, and Urokinase-type plasminogen activator, Uniprot P00734, P00747, P00749, P00750, P06870, and P07477
DOI: 10.7270/q2c828nc
title: BindingDB Entry 50012411: Spirocyclic NK(1) antagonists II: [4.5]-spiroethers.

description: Small molecule binding data for protein Neurokinin 1 receptor, Uniprot P25103
DOI: 10.7270/q2d50mcf
title: BindingDB Entry 50014406: Benzodiazepine-based selective inhibitors of mitochondrial F1F0 ATP hydrolase.

description: Small molecule binding data for protein Cytochrome P450 2C9 and Mitochondrial complex V; ATP synthase, Uniprot P00829, P05630, P05631, P05632, and P11712
DOI: 10.7270/q2f76c54
title: BindingDB Entry 50017863: Discovery of a novel, orally active, small molecule gonadotropin-releasing hormone (GnRH) receptor antagonist.

description: Small molecule binding data for protein 5-Hydroxytryptamine receptor 2A (5-HT2A), 5-Hydroxytryptamine receptor 2C (5-HT2C), 5-Hydroxytryptamine receptor 7 (5-HT7), Adenosine receptor A3, Angiotensin II type 1a (AT-1a)/1b (AT-1b) receptor, Cytochrome P450 1A, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), Cytochrome P450 3A, Dopamine D1 and D2 receptor, Dopamine receptor, Dopamine receptors; D2 & D4, Gonadotropin releasing hormone 1 (GnRHR1), Gonadotropin-releasing hormone receptor, Histamine H2 Receptor, Kappa-type opioid receptor, Mu-type opioid receptor, Muscarinic acetylcholine receptor M1, Muscarinic acetylcholine receptor M2 and M4, Neurokinin 1 receptor, Platelet activating factor receptor, Serotonin and norepinephrine transporters (SERT/NET), Sodium-dependent dopamine transporter, Sodium-dependent noradrenaline transporter, and Voltage-gated calcium channel subunit alpha Cav2.2, Uniprot P05177, P08173, P08684, P0DMS8, P10635, P11229, P11712, P21728, P21917, P23975, P25021, P25103, P25105, P28223, P28335, P30556, P30968, P30969, P31645, P33261, P34969, P35372, P35462, P41145, Q00975, and Q01959
DOI: 10.7270/q2fj2g89
title: BindingDB Entry 50016066: Synthesis and pharmacology of N1-substituted piperazine-2,3-dicarboxylic acid derivatives acting as NMDA receptor antagonists.

description: Small molecule binding data for protein Glutamate [NMDA] receptor subunit epsilon 1/zeta 1, Glutamate [NMDA] receptor subunit epsilon 2/zeta 1, and Glutamate [NMDA] receptor subunit epsilon 3/zeta 1, Uniprot P35439, Q00959, Q00960, and Q00961
DOI: 10.7270/q2gh9hg1
title: BindingDB Entry 50016044: Discovery of bicycloalkyl urea melanin concentrating hormone receptor antagonists: orally efficacious antiobesity therapeutics.

description: Small molecule binding data for protein GPR145, Melanin-concentrating hormone receptor, and Melanin-concentrating hormone receptor 1, Uniprot Q969V1 and Q99705
DOI: 10.7270/q2h131c3
title: BindingDB Entry 50012409: Design and characterization of non-phosphopeptide inhibitors for Src family SH2 domains.

description: Small molecule binding data for protein SRC and VEGF-receptor 2 and tyrosine-protein kinase SRC, Uniprot P06239, P06241, and P12931
DOI: 10.7270/q2ht2nsg
title: BindingDB Entry 50014404: 4-Substituted anilides as selective melatonin MT2 receptor agonists.

description: Small molecule binding data for protein Melatonin receptor, Uniprot P48039 and P49286
DOI: 10.7270/q2k073v0
title: BindingDB Entry 50017862: Structure-activity relationships of new 1H-imidazo[4,5-c]quinolin-4-amine derivatives as allosteric enhancers of the A3 adenosine receptor.

description: Small molecule binding data for protein Adenosine receptor A1, Adenosine receptor A2a, and Adenosine receptor A3, Uniprot P0DMS8, P29274, and P30542
DOI: 10.7270/q2nk3dgr
title: BindingDB Entry 50014400: Pyrazino[1,2-a]indoles as novel high-affinity and selective imidazoline I(2) receptor ligands.

description: Small molecule binding data for protein Serotonin (5-HT) receptor, Uniprot P14842
DOI: 10.7270/q2pr7vk1
title: BindingDB Entry 50017860: Substituent effects of N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamides on positive allosteric modulation of the metabotropic glutamate-5 receptor in rat cortical astrocytes.

description: Small molecule binding data for protein Metabotropic glutamate receptor, Uniprot P31424
DOI: 10.7270/q2q23zrd
title: BindingDB Entry 50016057: Substituted 5,5'-diphenyl-2-thioxoimidazolidin-4-one as CB1 cannabinoid receptor ligands: synthesis and pharmacological evaluation.

description: Small molecule binding data for protein Cannabinoid receptor 1, Uniprot P21554
DOI: 10.7270/q2rf5tcp
title: BindingDB Entry 50012401: Piperidine analogues of 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine (GBR 12909): high affinity ligands for the dopamine transporter.

description: Small molecule binding data for protein Serotonin and norepinephrine transporters (SERT/NET), Sodium-dependent dopamine transporter, and Sodium-dependent noradrenaline transporter, Uniprot P23975, P31645, and Q01959
DOI: 10.7270/q2sb456g
title: BindingDB Entry 50014399: Binding of beta-carbolines at imidazoline I2 receptors: a structure-affinity investigation.

description: Small molecule binding data for protein Adrenergic receptor alpha, Adrenergic receptor alpha-2, Imidazoline receptor 1 (I1R), and Serotonin (5-HT) receptor, Uniprot P14842, P19328, P22909, and Q9Y2I1
DOI: 10.7270/q2th8m9r
title: BindingDB Entry 50017858: A combination of docking/dynamics simulations and pharmacophoric modeling to discover new dual c-Src/Abl kinase inhibitors.

description: Small molecule binding data for protein Tyrosine-protein kinase ABL1 and VEGF-receptor 2 and tyrosine-protein kinase SRC, Uniprot P00519 and P12931
DOI: 10.7270/q2tt4qgt
title: BindingDB Entry 50016056: CoMFA and CoMSIA investigations revealing novel insights into the binding modes of dopamine D3 receptor agonists.

description: Small molecule binding data for protein DRD1, Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor, Dopamine receptor, Dopamine receptor D2L/neurotensin receptor NTS1, and Dopamine receptors; D2 & D4, Uniprot P14416, P21917, P35462, P61169, and Q95136
DOI: 10.7270/q2vt1rm6
title: BindingDB Entry 50016041: Discovery of a novel series of peroxisome proliferator-activated receptor alpha/gamma dual agonists for the treatment of type 2 diabetes and dyslipidemia.

description: Small molecule binding data for protein Peroxisome proliferator-activated receptor, Peroxisome proliferator-activated receptor alpha, and Peroxisome proliferator-activated receptor alpha (PPAR alpha), Uniprot P23204, P37231, Q07869, and Q95N78
DOI: 10.7270/q2w66k3d
title: BindingDB Entry 50012400: Inhibition of the antibacterial target UDP-(3-O-acyl)-N-acetylglucosamine deacetylase (LpxC): isoxazoline zinc amidase inhibitors bearing diverse metal binding groups.

description: Small molecule binding data for protein UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase (LxpC), Uniprot P0A725
DOI: 10.7270/q2x34wxd
title: BindingDB Entry 50014398: Design, synthesis, and SAR of anthranilamide-based factor Xa inhibitors with improved functional activity.

description: Small molecule binding data for protein Coagulation factor X/antithrombin III, Plasma kallikrein (KLKB1), Plasminogen, Prothrombin, Tissue-type plasminogen activator, Trypsin-1, and Vitamin K-dependent protein C, Uniprot P00734, P00742, P00747, P00750, P03952, P04070, and P07477
DOI: 10.7270/q2z89c1g
title: BindingDB Entry 50017852: Conformationally constrained analogues of diacylglycerol. 26. Exploring the chemical space surrounding the C1 domain of protein kinase C with DAG-lactones containing aryl groups at the sn-1 and sn-2 positions.

description: Small molecule binding data for protein Protein kinase C alpha type and Protein kinase C delta type, Uniprot P17252 and Q05655
DOI: 10.7270/q2zk5g53
title: BindingDB Entry 50016055: Architecture of the human urotensin II receptor: comparison of the binding domains of peptide and non-peptide urotensin II agonists.

description: Small molecule binding data for protein Urotensin II receptor, Uniprot Q9UKP6
DOI: 10.7270/q2125s8m
title: BindingDB Entry 50017890: 7-(aryl/heteroaryl-2-ylethynyl)-4-phenylamino-3-quinolinecarbonitriles as new Src kinase inhibitors: addition of water solubilizing groups.

description: Small molecule binding data for protein VEGF-receptor 2 and tyrosine-protein kinase SRC, Uniprot P12931
DOI: 10.7270/q22b8xj2
title: BindingDB Entry 50016078: Binding of isotryptamines and indenes at h5-HT6 serotonin receptors.

description: Small molecule binding data for protein 5-Hydroxytryptamine receptor 6 (5-HT6), Uniprot P50406
DOI: 10.7270/q22r3r02
title: BindingDB Entry 50012442: Dicarboxylic acid bis(L-prolyl-pyrrolidine) amides as prolyl oligopeptidase inhibitors.

description: Small molecule binding data for protein Prolyl endopeptidase, Uniprot P23687
DOI: 10.7270/q24t6j01
title: BindingDB Entry 50017889: Estrogen receptor beta-subtype selective tetrahydrofluorenones: use of a fused pyrazole as a phenol bioisostere.

description: Small molecule binding data for protein Estradiol receptor alpha (ERα) and Estradiol receptor beta (ERβ), Uniprot P03372 and Q92731
DOI: 10.7270/q25t3k3z
title: BindingDB Entry 50017872: Design, synthesis, and biological evaluation of novel tricyclic HIV-1 integrase inhibitors by modification of its pyridine ring.

description: Small molecule binding data for protein Human immunodeficiency virus type 1 integrase
DOI: 10.7270/q2610zt5
title: BindingDB Entry 50016076: Substituted aminobenzimidazole pyrimidines as cyclin-dependent kinase inhibitors.

description: Small molecule binding data for protein Cyclin-dependent kinase 1, Cyclin-dependent kinase 4, and Mitogen-activated protein kinase 3, Uniprot P06493, P11802, and P27361
DOI: 10.7270/q26h4gqc
title: BindingDB Entry 50012441: Synthesis of novel 4,1-benzoxazepine derivatives as squalene synthase inhibitors and their inhibition of cholesterol synthesis.

description: Small molecule binding data for protein Squalene synthetase, Uniprot P37268
DOI: 10.7270/q27d2tk7
title: BindingDB Entry 50014424: Tricyclic pyridones as functionally selective human GABAA alpha 2/3 receptor-ion channel ligands.

description: Small molecule binding data for protein GABA A Alpha4Beta2Gamma2, GABA A receptor alpha-2/beta-2/gamma-2, GABA A receptor alpha-6/beta-2/gamma-2, GABA receptor alpha-1/beta-3/gamma-2 subunit, GABA receptor alpha-3/beta-3/gamma-2 subunit, and Gamma-aminobutyric acid receptor subunit alpha-5 (GABA(A)), Uniprot P14867, P18507, P28472, P31644, P34903, P47869, P48169, and Q16445
DOI: 10.7270/q28k78qb
title: BindingDB Entry 50017887: P2-P4 macrocyclic inhibitors of hepatitis C virus NS3-4A serine protease.

description: Small molecule binding data for protein Hepatitis C virus serine protease, NS3/NS4A, Uniprot Q4JMH3 A3EZI9
DOI: 10.7270/q28s4pfn
title: BindingDB Entry 50016097: Discovery, synthesis and biological evaluation of novel glucokinase activators.

description: Small molecule binding data for protein Hexokinase type IV, Uniprot P35557
DOI: 10.7270/q29s1qh4
title: BindingDB Entry 50016071: Anchor-GRIND: filling the gap between standard 3D QSAR and the GRid-INdependent descriptors.

description: Small molecule binding data for protein Acetylcholinesterase and Genome polyprotein, Uniprot P22303 and P26664
DOI: 10.7270/q2b857f3
title: BindingDB Entry 50012440: 4-Substituted D-glutamic acid analogues: the first potent inhibitors of glutamate racemase (MurI) enzyme with antibacterial activity.

description: Small molecule binding data for protein Glutamate racemase, Uniprot Q03469
DOI: 10.7270/q2c53k9z
title: BindingDB Entry 50014423: Design and synthesis of macrocyclic inhibitors of phosphatase cdc25B.

description: Small molecule binding data for protein Dual specificity phosphatase Cdc25B, Uniprot P30305
DOI: 10.7270/q2db81f2
title: BindingDB Entry 50017884: Amino substituted analogs of 1-phenyl-3-phenylimino-2-indolones with potent galanin Gal3 receptor binding affinity and improved solubility.

description: Small molecule binding data for protein Alpha-1A adrenergic receptor, Dopamine D5 receptor, and Galanin receptor 3, Uniprot O60755, P21918, and P35348
DOI: 10.7270/q2dj5f4x
title: BindingDB Entry 50016095: Design, synthesis and activity of novel derivatives of oxybutynin and tolterodine.

description: Small molecule binding data for protein Muscarinic receptor M2 and M3, Uniprot P08483 and P10980
DOI: 10.7270/q2g1605t
title: BindingDB Entry 50012438: Inactivation and inhibition of gamma-aminobutyric acid aminotransferase by conformationally restricted vigabatrin analogues.

description: Small molecule binding data for protein Gamma-amino-N-butyrate transaminase, Uniprot P80404
DOI: 10.7270/q2gx4b0x
title: BindingDB Entry 50014422: Inhibitory activities against topoisomerase I and II by polyhydroxybenzoyl amide derivatives and their structure-activity relationship.

description: Small molecule binding data for protein DNA topoisomerase I (Topo I), Uniprot P11387
DOI: 10.7270/q2j102s2
title: BindingDB Entry 50017880: Synthesis and pharmacological characterization of novel fluorescent histamine H2-receptor ligands derived from aminopotentidine.

description: Small molecule binding data for protein Histamine H2 Receptor and Histamine H2 receptor, Uniprot P25021 and P47747
DOI: 10.7270/q2k9371g
title: BindingDB Entry 50016060: Fluorinated diaryl sulfides as serotonin transporter ligands: synthesis, structure-activity relationship study, and in vivo evaluation of fluorine-18-labeled compounds as PET imaging agents.

description: Small molecule binding data for protein Serotonin and norepinephrine transporters (SERT/NET), Sodium-dependent dopamine transporter, and Sodium-dependent noradrenaline transporter, Uniprot P23975, P31645, and Q01959
DOI: 10.7270/q2ks6qwf
title: BindingDB Entry 50012435: Enhancement of nucleoside cytotoxicity through nucleotide prodrugs.

description: Small molecule binding data for protein DNA polymerase (alpha/delta/epsilon), Uniprot P09884
DOI: 10.7270/q2mk6cbc
title: BindingDB Entry 50014420: Lactams as EP4 prostanoid receptor subtype selective agonists. Part 1: 2-Pyrrolidinones-stereochemical and lower side-chain optimization.

description: Small molecule binding data for protein Prostaglandin E2 receptor, Prostaglandin E2 receptor EP1 subtype (EP1), Prostaglandin E2 receptor EP2 subtype (EP2), and Prostaglandin E2 receptor EP4 subtype (EP4), Uniprot P34995, P35408, P43115, and P43116
DOI: 10.7270/q2ns0tgn
title: BindingDB Entry 50017877: The synthesis and SAR of 2-arylsulfanylphenyl-1-oxyalkylamino acids as GlyT-1 inhibitors.

description: Small molecule binding data for protein Glycine transporter 1, Uniprot P48067
DOI: 10.7270/q2p26xng
title: BindingDB Entry 50016089: A general carbometalation, three component coupling strategy for the synthesis of alpha,beta-unsaturated gamma-sultines including thio-rofecoxib, a selective COX-2 inhibitor.

description: Small molecule binding data for protein Cyclooxygenase, Uniprot P35354
DOI: 10.7270/q2pk0fhs
title: BindingDB Entry 50012452: Design, synthesis and evaluation of 4-imidazolylflavans as new leads for aromatase inhibition.

description: Small molecule binding data for protein Aromatase (CYP19), Uniprot P11511
DOI: 10.7270/q2qj7gm5
title: BindingDB Entry 50012430: Discovery and SAR of a novel selective and orally bioavailable nonpeptide classical competitive inhibitor class of protein-tyrosine phosphatase 1B.

description: Small molecule binding data for protein Protein-tyrosine phosphatase 1B, Protein-tyrosine phosphatase alpha, Receptor-type tyrosine-protein phosphatase F (LAR), T-cell protein-tyrosine phosphatase, and Tyrosine-Protein Phosphatase (CD45), Uniprot P08575, P10586, P17706, P18031, and P18433
DOI: 10.7270/q2rb741n
title: BindingDB Entry 50014418: Discovery of N-propylurea 3-benzylpiperidines as selective CC chemokine receptor-3 (CCR3) antagonists.

description: Small molecule binding data for protein 5-Hydroxytryptamine receptor 2A (5-HT2A) and C-C chemokine receptor type 3, Uniprot P28223 and P51677
DOI: 10.7270/q2sj1k6c
title: BindingDB Entry 50017876: Discovery of 3-hydroxy-4-carboxyalkylamidino-5-arylamino-isothiazoles as potent MEK1 inhibitors.

description: Small molecule binding data for protein Dual specificity mitogen-activated protein kinase kinase 1, Uniprot Q02750
DOI: 10.7270/q2st7pcw
title: BindingDB Entry 50016087: Kinesin spindle protein (KSP) inhibitors. Part 1: The discovery of 3,5-diaryl-4,5-dihydropyrazoles as potent and selective inhibitors of the mitotic kinesin KSP.

description: Small molecule binding data for protein Caspase-3 and Kinesin-like protein 1, Uniprot P42574 and P52732
DOI: 10.7270/q2v69hzm
title: BindingDB Entry 50012427: A sorbitol dehydrogenase inhibitor of exceptional in vivo potency with a long duration of action: 1-(R)-[4-[4-(4,6-dimethyl[1,3,5]triazin-2-yl)- 2R,6S-dimethylpiperazin-1-yl]pyrimidin-2- yl]ethanol.

description: Small molecule binding data for protein Sorbitol dehydrogenase, Uniprot P27867 and Q00796
DOI: 10.7270/q2w37vrk
title: BindingDB Entry 50014413: Discovery and SAR of trisubstituted thiazolidinones as CCR4 antagonists.

description: Small molecule binding data for protein C-C chemokine receptor type 4 (CCR4), Uniprot P51679
DOI: 10.7270/q2x929w7
title: BindingDB Entry 50017875: Novel, potent, selective, and orally bioavailable human betaII-tryptase inhibitors.

description: Small molecule binding data for protein Beta-chymotrypsin, Chymase, Granzyme K, Plasma kallikrein (KLKB1), Plasminogen, Prothrombin, Tryptase, Tryptase alpha/beta-1, Tryptase beta-1/beta-2, Urokinase-type plasminogen activator, and Vitamin K-dependent protein C, Uniprot P00734, P00747, P00749, P03952, P04070, P15944, P23946, P27435, P49863, Q02844, and Q15661,P20231