cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.9927857.v1
title: Prevalence of Sexual Dysfunctions and their Associated Factors in Pregnant Women in an Outpatient Prenatal Care Clinic

description: Abstract Objective To determine the prevalence of sexual dysfunction and its associated factors in pregnant women. Methods A descriptive, cross-sectional study including 262 pregnant women aged 18 years or older with gestational age between 10 and 35 weeks. Women with urinary tract infections and conditions of gestational risk were excluded. The Pregnancy Sexual Response Inventory (PSRI) questionnaire was used. We performed a univariate descriptive analysis, and comparisons between the mean values of the sexual function domains were made using the Student t-test. The chi-squared test was used to determine the association between the independent and dependent variables. The prevalence ratios, with their respective 95% confidence intervals, were also estimated, and a multivariate analysis was performed. Results A total of 64.9% of women reported a decrease in the frequency of sexual activity during pregnancy. Slightly more than half of the women (50.8%) were satisfied, and arousal was reported as excellent/good by 30.5% of them. The frequency of sexual difficulties/dysfunctions increased with pregnancy, rising from 5.7% to 58.8%, and pain during sexual intercourse was reported by 45.8% of them. Having higher education degree decreased the chance of being sexually dissatisfied by 50%. The total PSRI score showed a significant decrease from the prepregnancy period (mean score = 89.8, “excellent”) to the pregnancy period (mean score = 59.2, “good”). Conclusion The mean sexual function score during pregnancy was classified as good, although most pregnant women reported at least one type of alteration in the sexual function domains, and the report of dissatisfaction was more frequent in women with lower schooling.
DOI: 10.6084/m9.figshare.9927848.v1
title: Vulnerability of ecosystems with Guadua angustifolia in Ecuador in light of climate changes1

description: ABSTRACT Guadua angustifolia bamboo is historically used by an important percentage of the rural and peri-urban population of Ecuador, especially in the construction of bridges, when events like El Niño and its consequential flooding occur. This study aimed to determine, in light of some climate change scenarios, the vulnerability rate of ecosystems where the G. angustifolia bamboo species occurs, in the coastal region of continental Ecuador. The analysis methodology, with focus on the sampled units, was based on vulnerability assessment tools for climate adaptation recommended by the Intergovernmental Panel on Climate Change.Temperature presented the highest correlation coefficient with the vulnerability rate of the ecosystems, followed by the increase in the sea level, winds and landslides. It was concluded that as the exposure and sensitivity variables increase, the adaptive capacity of ecosystems with occurence of this species decreases, and isolated plants and monoculture plantations are the most vulnerable to climate changes.
DOI: 10.6084/m9.figshare.9927830
title: School desks models proposed by the General Direction of Public Instruction of Portugal (1877): the reference of The Vienna Universal Exhibition

description: ABSTRACT In the present article it is admitted that the material culture constitutes an essential source to get to know the past of schools. According to this view, several models of school desks proposed by the General Direction of Public Instruction of Portugal in the year of 1877 are analyzed. One of the defended ideas is that the diffusion of the mentioned models is legitimized in the reference to the foreign experience, namely, to a model of school desk (system of Kunze) presented in the Universal Exhibition of Vienna of Austria (1873). Since the school desk is one of the exponents of the student's officialisation process, what is observed in the host context is that the permeability to the conveyed knowledge (e.g., the external model) is minimal. In other words, a resistance to the classification and standardization created by universal exhibitions is observed at local level; expression, among others, of a certain pedagogical reality.
DOI: 10.6084/m9.figshare.9927830.v1
title: School desks models proposed by the General Direction of Public Instruction of Portugal (1877): the reference of The Vienna Universal Exhibition

description: ABSTRACT In the present article it is admitted that the material culture constitutes an essential source to get to know the past of schools. According to this view, several models of school desks proposed by the General Direction of Public Instruction of Portugal in the year of 1877 are analyzed. One of the defended ideas is that the diffusion of the mentioned models is legitimized in the reference to the foreign experience, namely, to a model of school desk (system of Kunze) presented in the Universal Exhibition of Vienna of Austria (1873). Since the school desk is one of the exponents of the student's officialisation process, what is observed in the host context is that the permeability to the conveyed knowledge (e.g., the external model) is minimal. In other words, a resistance to the classification and standardization created by universal exhibitions is observed at local level; expression, among others, of a certain pedagogical reality.
DOI: 10.6084/m9.figshare.9927833
title: Assessing the overall medication use by elderly people in a Brazilian hospital using the start/stopp criteria version 2

description: To estimate the frequency of the use of medicines listed in the Screening Tool to Alert Doctors to the Right Treatment (START) and Screening Tool of Older Person’s Prescriptions (STOPP) criteria version 2 among the elderly. A cross-sectional study was conducted on elderly who were attended in medical clinic and cardiology sectors in a hospital in southern Brazil attended at a hospital from February through September 2016. A data-collection tool was used to obtain information on variables, such as demographic and clinical data, and medications used before and during the hospitalization period. The adequacy of the medicines taken was examined with regard to omission (START) or inappropriate use (STOPP). This study was approved by the Research Ethics Committee of the University of Southern Santa Catarina. A total of 307 subjects were included in the final sample. The mean age was 75.2 years (SD = 8; range 65-102). Of the total, 93.5% had had at least one potential prescribing omission (PPO) listed in the START criteria, whereas 95.4% used at least one medicine of the STOPP criteria. PPO was significantly associated with lower mean age (74.9 years, SD = 7.9 versus 79.0 years, SD = 8.8) among the elderly who did not have PPOs detected by the START criteria (p-value=0.03). Furthermore, PPO was associated with longer hospital stay (18 versus 9 days; p-value=0.03). This study revealed inadequate prescription affecting 99.3% of the participating patients. To the best of our knowledge, this was the first to use the START and STOPP criteria, version 2, in Brazil.
DOI: 10.6084/m9.figshare.9927821
title: BROMELAIN SEPARATION AND PURIFICATION PROCESSES FROM PINEAPPLE EXTRACT

description: Abstract The concern about the effective use of agro-industrial residues from the food industry has increased. Bromelain is an enzyme mainly obtained from the pineapple plant (A. comosus), including its parts normally considered as waste. It is a high value-added product with a wide variety of applications such as in food, cosmetic and pharmaceutical industries. Many approaches have been used to purify this enzyme, but an efficient method to produce highly active and pure bromelain is still highly desirable. The investigated methods include ion exchange chromatography, precipitation, an aqueous two-phase system as well as affinity and filtration membranes. This paper gives an overview about the advantages and limitations of each one. Chronologic results and advances for these separation processes are also shown. The major tendency is the use of combined processes, such as hybrid or integrated ones.
DOI: 10.6084/m9.figshare.9927824
title: OPTIMIZATION OF HIGH-CONCENTRATION TRANS-ANETHOLE PRODUCTION THROUGH HYDRODISTILLATION OF STAR ANISE

description: Abstract Illicium verum Hook essential oil (EO) is composed mainly of trans-anethole (TA), which has therapeutic potential. The extraction is usually by hydrodistillation, taking long hours, leaving the process costly and product with lower quality. Thus, the present study sought to optimize dehydrated fruit fragmentation by Box-Wilson central composite design and EO extraction and EO quality using a 24-1 fractional factorial design. It is concluded that the fruits must be fragmented to sizes smaller than 425 μm using a knife mill. For hydrodistillation, the condition reported as ideal was granulometry &lt; 0.425 mm, 8% mass, 1 hour and water volume of 200 mL. This process provided an EO yield of 10.2% and high-grade TA (96.6%), requiring shorter time of extraction.
DOI: 10.6084/m9.figshare.9927833.v1
title: Assessing the overall medication use by elderly people in a Brazilian hospital using the start/stopp criteria version 2

description: To estimate the frequency of the use of medicines listed in the Screening Tool to Alert Doctors to the Right Treatment (START) and Screening Tool of Older Person’s Prescriptions (STOPP) criteria version 2 among the elderly. A cross-sectional study was conducted on elderly who were attended in medical clinic and cardiology sectors in a hospital in southern Brazil attended at a hospital from February through September 2016. A data-collection tool was used to obtain information on variables, such as demographic and clinical data, and medications used before and during the hospitalization period. The adequacy of the medicines taken was examined with regard to omission (START) or inappropriate use (STOPP). This study was approved by the Research Ethics Committee of the University of Southern Santa Catarina. A total of 307 subjects were included in the final sample. The mean age was 75.2 years (SD = 8; range 65-102). Of the total, 93.5% had had at least one potential prescribing omission (PPO) listed in the START criteria, whereas 95.4% used at least one medicine of the STOPP criteria. PPO was significantly associated with lower mean age (74.9 years, SD = 7.9 versus 79.0 years, SD = 8.8) among the elderly who did not have PPOs detected by the START criteria (p-value=0.03). Furthermore, PPO was associated with longer hospital stay (18 versus 9 days; p-value=0.03). This study revealed inadequate prescription affecting 99.3% of the participating patients. To the best of our knowledge, this was the first to use the START and STOPP criteria, version 2, in Brazil.
DOI: 10.6084/m9.figshare.9927824.v1
title: OPTIMIZATION OF HIGH-CONCENTRATION TRANS-ANETHOLE PRODUCTION THROUGH HYDRODISTILLATION OF STAR ANISE

description: Abstract Illicium verum Hook essential oil (EO) is composed mainly of trans-anethole (TA), which has therapeutic potential. The extraction is usually by hydrodistillation, taking long hours, leaving the process costly and product with lower quality. Thus, the present study sought to optimize dehydrated fruit fragmentation by Box-Wilson central composite design and EO extraction and EO quality using a 24-1 fractional factorial design. It is concluded that the fruits must be fragmented to sizes smaller than 425 μm using a knife mill. For hydrodistillation, the condition reported as ideal was granulometry &lt; 0.425 mm, 8% mass, 1 hour and water volume of 200 mL. This process provided an EO yield of 10.2% and high-grade TA (96.6%), requiring shorter time of extraction.
DOI: 10.6084/m9.figshare.9927815
title: EFFECT OF ALUMINUM SULFATE AND CATIONIC POLYMER ADDITION IN THE MIXED LIQUOR OF A SUBMERGED MEMBRANE BIOREACTOR (SMBR): SLUDGE CHARACTERISTICS AND ORTHOPHOSPHATE REMOVAL IN BATCH EXPERIMENTS

description: Abstract Submerged Membranes Bioreactors (SMBR) are an established technology for wastewater treatment for water recovery and reuse. However, its routine application is still compromised by the high energy consumption to overcome the fouling effect. This study evaluated the effect of aluminum sulfate and cationic polymer in the orthophosphate removal and sludge filterability improvement in the mixed liquor of a SMBR pilot system. Parameters such as coagulant concentration, filtration time, extracellular polymeric substances (EPS) reduction and orthophosphate removal were evaluated by using a jar-test and a stirred cell. As results, aluminum sulfate and polymer additions improved the filtration index (FI30) from 25% to 32 %, for both chemicals. Time-to-filter (TTF) results evidenced a positive and significant correlation between aluminum sulfate dosage and colloidal EPS reduction.
DOI: 10.6084/m9.figshare.9927818
title: HYDROXYAPATITE - CARBON NANOTUBE COMPOSITES FOR DRUG DELIVERY APPLICATIONS

description: Abstract The aim of this study was the synthesis of composites containing hydroxyapatite (Hap) or silicon substituted hydroxyapatite (HapSi), carboxyl functionalized carbon nanotubes (fMWCNT) and gelatin (G) in different ratios. Ibuprofen (IBU) was chosen as a model drug for the formulation of extended-release dosage forms. The obtained composites were characterized using X-ray diffraction, laser diffraction particle size analyzer, Brunauer-Emmett-Teller surface area measurements, transmission electron microscopy and Fourier transformed infrared spectroscopy. IBU adsorption and desorption was monitored by UV-VIS spectroscopy. The obtained results revealed that composites containing three components exhibit higher adsorption efficiency (Hap-fMWCNT-20G - 82.7% and HapSi-fMWCNT-20G - 84.6%) and extended-release of IBU, due to the chemical bonds between the carboxyl groups of IBU and the functional groups on the composite surface. The adsorption capacity of Hap composites is important for dental or orthopedic implants, the anti-inflammatory substances being adsorbed on their surface; but the adsorption capacity also enhances new bone formation (osteosynthesis) around the implants. These composites are thus attractive materials to be used in bone tissue engineering and drug delivery systems.
DOI: 10.6084/m9.figshare.9927821.v1
title: BROMELAIN SEPARATION AND PURIFICATION PROCESSES FROM PINEAPPLE EXTRACT

description: Abstract The concern about the effective use of agro-industrial residues from the food industry has increased. Bromelain is an enzyme mainly obtained from the pineapple plant (A. comosus), including its parts normally considered as waste. It is a high value-added product with a wide variety of applications such as in food, cosmetic and pharmaceutical industries. Many approaches have been used to purify this enzyme, but an efficient method to produce highly active and pure bromelain is still highly desirable. The investigated methods include ion exchange chromatography, precipitation, an aqueous two-phase system as well as affinity and filtration membranes. This paper gives an overview about the advantages and limitations of each one. Chronologic results and advances for these separation processes are also shown. The major tendency is the use of combined processes, such as hybrid or integrated ones.
DOI: 10.6084/m9.figshare.9927809
title: Sandflies in an endemic area for Visceral Leishmaniasis in Northeastern Brazil

description: Abstract Phlebotomines of the genus Lutzomyia are important vector for species of Leishmania, the etiological agent of leishmaniasis. The aim of this study was to assess the diversity of sandflies in an endemic area for Visceral Leishmaniasis (VL). Sampling was performed in four localities on the coast of the municipality of Goiana, state of Pernambuco, Northeastern Brazil. Specimens were collected monthly on three consecutive nights, from November 2017 to October 2018. CDC light traps were installed at a height of 1.5 m above the ground, in two ecotypes (i.e. tree and animal facility), both in peridomestic areas. A total of 5,205 sandflies were collected, among which the species Lutzomyia longipalpis (99.85%; 5,197/5,205) was the most common, followed by Lutzomyia evandroi (0.13%; 07/5,205) and Lutzomyia whitmani (0.02%; 01/5,205). Specimens of L. longipalpis were collected throughout the study period and most of them were found near to the animal facilities. The findings from this research indicate that vectors for Leishmania infantum are present in the study area throughout the year, along with occurrences of vectors relating to Cutaneous Leishmaniasis (CL). Preventive vector control measures need to be implemented in Goiana to reduce the risk of infection for the human and animal populations.
DOI: 10.6084/m9.figshare.9927818.v1
title: HYDROXYAPATITE - CARBON NANOTUBE COMPOSITES FOR DRUG DELIVERY APPLICATIONS

description: Abstract The aim of this study was the synthesis of composites containing hydroxyapatite (Hap) or silicon substituted hydroxyapatite (HapSi), carboxyl functionalized carbon nanotubes (fMWCNT) and gelatin (G) in different ratios. Ibuprofen (IBU) was chosen as a model drug for the formulation of extended-release dosage forms. The obtained composites were characterized using X-ray diffraction, laser diffraction particle size analyzer, Brunauer-Emmett-Teller surface area measurements, transmission electron microscopy and Fourier transformed infrared spectroscopy. IBU adsorption and desorption was monitored by UV-VIS spectroscopy. The obtained results revealed that composites containing three components exhibit higher adsorption efficiency (Hap-fMWCNT-20G - 82.7% and HapSi-fMWCNT-20G - 84.6%) and extended-release of IBU, due to the chemical bonds between the carboxyl groups of IBU and the functional groups on the composite surface. The adsorption capacity of Hap composites is important for dental or orthopedic implants, the anti-inflammatory substances being adsorbed on their surface; but the adsorption capacity also enhances new bone formation (osteosynthesis) around the implants. These composites are thus attractive materials to be used in bone tissue engineering and drug delivery systems.
DOI: 10.6084/m9.figshare.9927803
title: Oxyurid nematodes of pet rodents in Slovakia - a neglected zoonotic threat

description: Abstract The role of rodents as reservoirs of helminths of public health importance is not well known. The zoonotic potential of Syphacia spp. has been confirmed; therefore, the study aimed to estimate the occurrence of oxyurid nematodes in small rodents from pet shops and breeding clubs in Slovakia. Fecal samples of 586 pet rodents kept in 133 cages were collected between 2016 and 2018 and examined by Faust´s flotation method. Four species of oxyurid nematodes, Syphacia muris, S. obvelata, Aspiculuris tetraptera and Paraspidodera uncinata were detected. A. tetraptera was found in the faecal samples of all rodent species included in this survey. The number of positive boxes varied from 5.4% in hamsters to 70.0% with mice. The prevalence of Syphacia muris was highest in Mongolian gerbils where up to 75.0% boxes were positive; S. obvelata was found in 26.7% of boxes with mice, 25.0% of boxes with Mongolian gerbils and 3.2% of boxes with rats. The high prevalence of Syphacia spp. in all animal species points out the infection risk for humans. Animals offered for sale are often in close contact with human beings; therefore they should be regularly tested for parasites and then effectively dewormed.
DOI: 10.6084/m9.figshare.9927806
title: Molecular survey of flaviviruses and orthobunyaviruses in Amblyomma spp. ticks collected in Minas Gerais, Brazil

description: Abstract Due to anthropic environmental changes, vector-borne diseases are emerging worldwide. Ticks are known vectors of several pathogens of concern among humans and animals. In recent decades, several examples of tick-borne emerging viral diseases have been reported (Crimean Congo hemorrhagic fever virus, Powassan virus, encephalitis virus, heartland virus, severe fever with thrombocytopenia syndrome virus). Unfortunately, few studies addressing the presence of viruses in wild ticks have been carried out in South America. With the aim of detecting flaviviruses and orthobunyaviruses in ticks, we carried out molecular detection in wild ticks collected in the state of Minas Gerais, Brazil. No Flavivirus-positive ticks were detected; however, we detected activity of Orthobunyavirus in 8 Amblyomma tick specimens. One of those individuals was positive for Bunyamwera orthobunyavirus, which represents the first report of this virus among ticks in South America. Further studies related to the ecology of zoonotic diseases are needed to increase knowledge of this topic, including attempts at viral isolation, full genome sequencing and biological characterization. In this way, we will obtain a better picture of the real risk of ticks as a vector for viral diseases for humans and animals on our continent, where no tick-borne viral disease is known to occur.
DOI: 10.6084/m9.figshare.9927809.v1
title: Sandflies in an endemic area for Visceral Leishmaniasis in Northeastern Brazil

description: Abstract Phlebotomines of the genus Lutzomyia are important vector for species of Leishmania, the etiological agent of leishmaniasis. The aim of this study was to assess the diversity of sandflies in an endemic area for Visceral Leishmaniasis (VL). Sampling was performed in four localities on the coast of the municipality of Goiana, state of Pernambuco, Northeastern Brazil. Specimens were collected monthly on three consecutive nights, from November 2017 to October 2018. CDC light traps were installed at a height of 1.5 m above the ground, in two ecotypes (i.e. tree and animal facility), both in peridomestic areas. A total of 5,205 sandflies were collected, among which the species Lutzomyia longipalpis (99.85%; 5,197/5,205) was the most common, followed by Lutzomyia evandroi (0.13%; 07/5,205) and Lutzomyia whitmani (0.02%; 01/5,205). Specimens of L. longipalpis were collected throughout the study period and most of them were found near to the animal facilities. The findings from this research indicate that vectors for Leishmania infantum are present in the study area throughout the year, along with occurrences of vectors relating to Cutaneous Leishmaniasis (CL). Preventive vector control measures need to be implemented in Goiana to reduce the risk of infection for the human and animal populations.
DOI: 10.6084/m9.figshare.9927815.v1
title: EFFECT OF ALUMINUM SULFATE AND CATIONIC POLYMER ADDITION IN THE MIXED LIQUOR OF A SUBMERGED MEMBRANE BIOREACTOR (SMBR): SLUDGE CHARACTERISTICS AND ORTHOPHOSPHATE REMOVAL IN BATCH EXPERIMENTS

description: Abstract Submerged Membranes Bioreactors (SMBR) are an established technology for wastewater treatment for water recovery and reuse. However, its routine application is still compromised by the high energy consumption to overcome the fouling effect. This study evaluated the effect of aluminum sulfate and cationic polymer in the orthophosphate removal and sludge filterability improvement in the mixed liquor of a SMBR pilot system. Parameters such as coagulant concentration, filtration time, extracellular polymeric substances (EPS) reduction and orthophosphate removal were evaluated by using a jar-test and a stirred cell. As results, aluminum sulfate and polymer additions improved the filtration index (FI30) from 25% to 32 %, for both chemicals. Time-to-filter (TTF) results evidenced a positive and significant correlation between aluminum sulfate dosage and colloidal EPS reduction.