cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.14457/cu.the.2011.1094
title: Effects of curcumin on hepatitis in mice with paracetamol overdose

description: N-acetyl-p-aminophenol (APAP) or paracetamol overdose is metabolized by cytochrome P450 (CYP 2E1) and a toxic metabolite, mainly N-acetyl-p-benzoquinone imine (NAPQI) is formed, finally, liver injury occurs. Here, we examined the effects of curcumin attenuated hepatitis in mice with APAP overdose. Male mice (25-30 gram) were divided into four groups. Group I (Control); was gavaged with distilled water. Group II (APAP); was gavaged with a single dose of 400 mg/kg APAP dissolve in water. Group III (APAP + CUR 200); was gavaged with a single dose of 400 mg/kg APAP and 200 mg/kg curcumin. Group IV (APAP + CUR 600); was gavaged with a single dose of 400 mg/kg APAP and 600 mg/kg curcumin. The liver was collected for hepatic GSH, hepatic MDA, and liver pathology assays. The serum was collected for hepatic enzymes, IL-12, and IL-18 assays using ELISA technique. Hepatic MDA, hepatic enzymes, serum IL-12, and IL-18 were significantly increased in APAP as compared with control and significantly decreased in APAP + CUR 200 and APAP + CUR 600 as compared with APAP. Hepatic GSH was significantly decreased in APAP as compared with control and significantly increased in APAP + CUR 200 and APAP + CUR 600 as compared with APAP. Liver pathology of APAP showed extensive hemorrhagic hepatic necrosis involving all zones and the improvement of liver pathology revealed in APAP + CUR 200 and APAP + CUR 600. In conclusion, APAP overdose can cause liver injury. The results show that curcumin could attenuate APAP-induced liver injury by decrease oxidative stress, reduce liver inflammation, restoring hepatic GSH, and improve liver pathology. In addition, curcumin at the dose of 600 mg/kg tends to be more potent than 200 mg/kg in preventing the effects of APAP hepatotoxicity. Hence, curcumin might be a novel therapeutic strategy against hepatitis caused by APAP overdose.
DOI: 10.14457/cu.the.2011.1095
title: Comparison of mean serum vitamin D level among inactive SLE, active SLE without lupus nephritis and active SLE with lupus nephritis

description: Objectives: The primary objective of this study is to compare mean serum 25OHD in SLE patients with inactive disease, SLE patients with active disease but no LN and SLE patients with active disease and LN. The secondary objective is to determine clinical predictors of vitamin D deficiency in SLE patients. Methods: This prospective study included 108 SLE patients. Patients were classified as Group(Gr) 1,2 and 3 if the patients had SLE disease activity index2K(SLEDAI) &lt;3, ≥3 but no LN and ≥ 3 with LN. Serum 25OHD was measured by HPLC method. Results: Mean(SD) age and disease duration of patients was 35.2(11.1) and 7.9(8.3) years respectively. Mean SLEDAI in Gr1, Gr2, Gr3 was 0.7(0.9), 5.6(2.3) and 9.2(5.2) respectively. 47/108(43.5%) had vitamin D insufficiency(25OHD&lt;30ng/ml) and 32/108(29.6%) had vitamin D deficiency(25OHD&lt;20ng/ml). Mean 25OHD in each groups were 28.3(7.1), 26.7(9.5) and 19.9(7.6) ng/ml respectively. Patients with LN had significantly lower 25OHD than other groups (p=0.001). Serum 25OHD was significantly correlated with serum albumin(r=0.32, p=0.001), inversely correlated with SLEDAI(r=-0.30, p=0.002) and inversely correlated with UPCI(r=-0.39, p=0.001). Only UPCI was significantly inversely correlated with serum 25OHD with unstandardized coefficient -1.05(0.38) (p=0.007). Conclusion: SLE patients with LN have significantly lower vitamin D level than inactive SLE and active SLE without LN. Only UPCI is inversely correlated with 25OHD level.
DOI: 10.25919/5d9bbbba3bb08
title: Parkes observations for project P1005 semester 2019APRS_02

description: We propose to conduct observations of PSRs J1812-15 and J1831-04, a pair of 1-s pulsars which exhibit both nulling behaviour and clear evidence of acceleration, suggesting that they are in binary systems. Binary pulsars are valuable objects of scientific study, allowing for a wide range of applications, including tests of gravity, probes of the neutron star equation of state and fossil records of stellar evolution. Long spin-period pulsars in binary systems are generally much rarer than faster-spinning recycled pulsars, and represent an under-explored region of pulsar binary evolution. Due to the nulling behaviour of both PSRs J1812-15 and J1831-04, determination of an orbital or phase-connected solution has so far proved impossible, but both of these steps are vital in allowing for their continued study. We propose a targeted, high-cadence observing campaign designed to map the orbits of these pulsars while simultaneously factoring in the redundancy required in order to overcome their nulling behaviour. By studying these pulsars, we hope to provide new insight into an unusual class of pulsar binary, as well to constrain the nulling properties of both pulsars.
DOI: 10.14457/cu.the.2011.1096
title: Highly selective amperometric sensors for carbon monoxide monitoring

description: An amperometric carbon monoxide sensor using Fe-doped LaGaO₃ oxides as electrolyte was investigated. The electrodes which are Au10wt%-ITO955 (as cathode) and RuO₂-LSC64 (as anode) were coated on each side of the electrolyte and connected with Au mesh and Pt mesh, respectively. The fabricated sensor was placed inside a ceramic tube which was attached with a gas flow assembly and external electrical contacts. The operating temperature is in the range of 300℃ to 500℃. From this study, the perovskite compound doped with 15mol% Fe into Ga site (LSGF828515) showed the highest sensitivity and its sensitivity increased with increasing temperature. Moreover, the examined sensor exhibited higher selectivity to carbon monoxide compared with that of coexisting gases such as carbon dioxide, methane and hydrogen. Namely, the sensor has no significant responses to these coexisting gases, even hydrogen which is quite reactive to oxidation reaction. The effect of additive adding into anode (LSC64) was studied. It was found that LSC64 doped with Pt or Pd exhibited higher responses compared with that of non-doped LSC64 case. In addition, under sensing measurement conditions, there were no effects of gases or other factors on the sensor’s structure.
DOI: 10.14457/cu.the.2011.1097
title: Changes of colour appearance due to changes of shape of colour sample and background colour

description: Background is one of the important factors that affect colour appearance of samples. In general, a background colour induces colour appearance of a sample to shift towards the complementary colour of the background. For example, grey on black background appears lighter than the same grey on white background. Shape of colour sample is also a factor that can affect sense and mood of observers. The degree of colour shifts due to the background colour might be different for different shapes of colour samples. This study thus investigated this aspect. In visual experiments, the observers were 40 Thais, 20 women and 20 men, with an average age of 24.3 years, all with normal colour vision. Each observer matched colour appearance of square samples presented on a grey background with that of test samples with different shapes on a chromatic background. Six shapes, i.e. circle, square, diamond, isosceles triangle, right-angled triangle and hexagon, and four chromatic backgrounds, i.e. red, green, yellow and blue, were investigated. The differences between colours of the test and the matching samples were quantified by CIE total colour difference, ∆E*[subscript ab]. It was found that circle induced the most changes in colour appearance of the sample due to the influence of background colour and diamond showed the minimum induction. Both shape and background contributed to changes in colour appearance
DOI: 10.14457/cu.the.2011.1098
title: Layered zeolites intercalated with quaternary ammonium salts as catalysts for esterification of glycerol

description: This research aimed to study the preparation of MCM-22 intercalated with quaternary ammonium salts, including tetrapropylammonium hydroxide (TPAOH), tetrabutylammonium hydroxide (TBAOH), tetrabutylammonium acetate (TBAAC), and cetyltrimethylammonium bromide (CTAB). MCM-22(P) was synthesized by using hydrothermal method. MCM-22 and ITQ-2 were attained by calcination and delamination of MCM-22(P), respectively. The intercalation of MCM-22 with CTAB and TPAOH or TBAOH can be prepared by refluxing MCM-22(P) with the solution of TPAOH/CTAB or TBAOH/CTAB, respectively, at 80 ℃ for 16 h. MCM-22 and ITQ-2 were impregnated with phosphotungstic acid (HPW). The synthesized catalysts were characterized by means of X-ray diffraction (XRD), thermogravimetric/differential thermal analysis (TG/DTA), nitrogen adsorption-desorption technique, scanning electron microscopy (SEM), and acidity measurement. Effects of quaternary ammonium salt, phosphotungstic acid amount, molar ratio of glycerol to lauric acid, reaction temperature, catalyst amount, and reaction time on lauric acid conversion and products distribution were investigated. Due to an enhancement of the catalyst acidity, it was found that 40HPW/ITQ-2 giving the highest monoglycerides yield of 45.5% at the lauric acid conversion of 57.4% under the suitable conditions, the molar ratio of glycerol/lauric acid of 1, the catalyst mass of 4 wt.% based on weight of lauric acid, the reaction time of 5 h at 110 ℃.
DOI: 10.14457/cu.the.2011.1099
title: Insider trading in politically connected firms : an evidence from Thailand

description: Political connection can heavily affect the financial performance of a firm. Firms that are connected to a government official can benefit from various regulations, tax breaks, and concessions while firms that are connected to the opposition might suffer. Empirical results from various studies conclude that political connection is a significant factor in explaining excess return in listed firms. This study compares trading behavior of connected and unconnected during four categories of events which are change in government, change in public policy, display of favoritism, and unfavorable events. Market transaction and insider transaction data between 2001 and 2008 is obtained from the Stock Exchange of Thailand and the Securities Exchange Commission of Thailand respectively. This research uses cumulative abnormal return as proxy for excess return. Additionally the probability of information-based trading, buy-sell imbalance, and frequency imbalance is used as proxy for trading behavior. This study found that there is excess return in some political events and that insiders trade opportunistically to maximize profit (minimize loss). It can be concluded that not all type of political events are significant and that insiders sometimes trade before material information becomes public.
DOI: 10.14457/cu.the.2011.1100
title: Performance and cost estimations for web applications on Amazon elastic compute cloud

description: Web base application plays an important role in supporting online activities, such as E-business, contents distribution and a communication portal. There is a big increasing in number of online activity usage that leads to an important problem to a webserver which is a “traffic overload problem.” At present, the conventional solutions are whether to increase the number of webserver or to increase the capability of the server (more RAM, CPU, Cache, HDD). Unfortunately, these solutions bring about waste resulting from overloading problem that accounts for less than 25 percents of the operation time. In addition, hardware capacity has not been used to it maximum over than 70 percent of the time, but left idle instead. This study proposes a new method to solve this problem on Amazon Elastic Cloud Compute (EC2) service. The proposed solution relies on Auto Scaling where the number of system instances (web server) can be increased and decreased based on some pre-defined condition. In this case, the number of current system users is the main focus. An experiment showed that this method provided great performance. It was also found that focusing on tuning of system crontab variable was the most effective method and easiest for real practice. However, the proposed solution is only suitable for the system which predicted user distribution is in exponential form.
DOI: 10.14457/cu.the.2011.1101
title: Cloning of SHMT gene from a halotolerant cyanobacterium Aphanothecehalophytica and expression in Escherichia coli

description: Serine hydroxymethyltransferase (SHMT) is an important enzyme for serine-glycine cycles and plays important role as a central position in one-carbon metabolism. SHMT has been studied in many living organisms from bacteria to higher plants and mammals; however, biochemical and molecular characterization of SHMT has never been investigated in photoautotrophic microorganisms. In this study, we have isolated SHMT gene from a halotolerantcyanobacteriumAphanothecehalophytica (ApSHMT) and expressed in Escherichia coli. Recombinant ApSHMT exhibited catalytic reactions for both THF-dependent/independent cleavages. Catalytic reaction for L-serine, a physiological substrate, was strongly inhibited by NaCl but it could be protect efficiently by osmoprotectantbetaine. Amino acid analysis revealed the increased levels of amino acids (glycine and serine) in the expressing cells in all condition examined. Furthermore, metabolite analysis revealed alleviated levels of choline as well as betaine. ApSHMT expressing cells could accumulate betaine several folds higher than the control cells, which caused the enhanced growth rate of the expressing cells particularly under salt-stress conditions.
DOI: 10.14457/cu.the.2011.1102
title: Primalities of (R,S)-Submodules Of (R,S)-Modules and of left multiplication (R,S)-Modules

description: In this research, the notions of (R, S)-modules and left multiplication (R, S)-modules are introduced. We define and investigate fully prime (R, S)-submodules, jointly prime (R, S)-submodules and left R-prime (R, S)-submodules. Fully prime (R, S)-submodules and jointly prime (R, S)-submodules of a left multiplication (R, S)-module are shown to be identical. Moreover, characterizations of fully prime (R, S)-submodules, jointly prime (R, S)-submodules and left R-prime (R, S)-submodules of an (R, S)-module and of a left multiplication (R, S)-module are provided.
DOI: 10.14457/cu.the.2011.1103
title: Relative foreign direct investment attractiveness among ASEAN countries

description: This study aims to explore the determinants of inward FDI in 4 ASEAN countries, namely; Thailand, Malaysia, Indonesia and Vietnam, from selected home countries in ASEAN, and also to explore the causes for their differences in inward FDI. Panel Data Estimation was used to analyze the determinants of FDI in these 4 host countries from selected home countries in ASEAN. Oaxaca-Blinder decomposition was applied to examine the causes of the difference in inward FDI by quantifying the contribution of each explanatory variable to the total gap, as a percentage of the total FDI gap, with some of the differences in FDI inflows between host ASEAN countries can be explained by the differences in the characteristics, so one will be able to learn which factor contributes to the increase or decrease of FDI gap between host countries. Findings reveal that real wage helps to attract FDI into Thailand. Real GDP helps to attract FDI into Vietnam. Real exchange rate, real lending interest rate and geographic distance help to attract FDI into Malaysia. Real exports, real exchange rate and geographic distance help to increase FDI gap between Malaysia and other host countries; Vietnam and Thailand. Real GDP and real exchange rate helps to increase FDI gap between Indonesia and other host countries; Malaysia, Thailand and Vietnam. Real wage helps to increase FDI gap between Thailand and other host countries; Vietnam, Indonesia and Malaysia. Real exports, real imports and geographic distance help to increase FDI gap between Vietnam and other host countries; Malaysia and Indonesia.
DOI: 10.14457/cu.the.2011.1104
title: Gold nanoparticles on silver surface prepared by galvanic replacement reaction

description: A novel technique for fabricating complex gold micro/nanostructures including coral-liked, needle-liked, Zen stone-liked gold micro/nanostructures, and coral-liked gold micro/nanoporous film using galvanic replacement reaction between a sacrificed silver metal and gold (III) ion have been reported. The complex gold micro/nanostructures could be controlled by adjustable gold ion concentration, immersion time, chloride ion concentration, pH, and ultrasonic radiation. The structural evolutions of gold micro/nanostructures were observed by scanning electron microscope (SEM) with energy dispersive X-ray spectroscope (EDS), X-ray diffraction (XRD), and digital camera. The epitaxial growth of gold film on the silver surface was disturbed by the precipitated AgCl micro/nanoparticles. The co-development of AgCl precipitates and galvanic generated Au film induced a formation of Au/AgCl micro/nanocomposites on silver surface. AgCl and AgCl⁻₂ played important roles on the evolution of coral-liked, needled-liked gold nanostructures. The ultrasonic also induced an auto-detachment of the galvanic generated film along the Ag/AgCl interface. The complex gold nanostructures with nanoporous morphology were realized once the co-developed AgCl was removed. The coral-liked gold micro/nanoporous express high SERS detection up to 10⁻⁶ M rhodamine 6G (R6G) and crystal violet (CV).
DOI: 10.14457/cu.the.2011.1105
title: Detection of tetracycline-resistance Enterococcus spp. in ready-to-eat Thai traditional fermented products

description: This study detected tetracycline-resistance (Tcʳ) Enterococcus spp. in 70 samples of 5 different kinds of ready-to-eat Thai traditional fermented foods (fish, pork, crab, shrimp, and shell). It was found that 28 samples (40%) were contaminated with Tcʳ Enterococcus spp. All five different kinds of food samples were contaminated with Enterococcus spp. except for fermented shell. High percentage of Tcʳ Enterococcus spp. was found in isolates from fish and shrimp (77.46% and 57.89% respectively). The tetracycline minimum inhibitory concentration (TC MIC) of Enterococcus spp. was found between 16 and 512 µg/ml. Most of the enterococcal isolates had TC MIC in the range from &gt;64 to 128 µg/ml, except for isolated from crab that had MIC in the range from &gt;128 to 256 µg/ml. The high level of TC MIC (&gt;256-512 µg/ml) was only found in isolated from fish and crab. The clinically relevant Enterococcus spp. were also found including 46.15% E. faecalis and 35.58% E. faecium. E. faecalis was found only in fermented fish and pork but E. faecium was found in all 4 different kinds of fermented food. The results from this study indicated that some ready-to-eat Thai traditional fermented foods can be reservoir for transmission of antibiotic resistant enterococci or antimicrobial determinant which may cause serious health problem. In order to prevent this problem, the reduction of enterococcal contamination in food should be implemented including heat inactivation, properly cooked before consumption as well as good sanitation and hygiene practice in preparation of foods. Moreover, restriction of using antibiotic in animal feed and aquaculture should be in consideration.
DOI: 10.14457/cu.the.2011.1106
title: Application of plasma-modified single-walled carbon nanohorns for PVPI slow release

description: In this work, SWCNHs synthesized by gas-injected arc-in-water (GI-AIW) method have been modified by oxygen plasma for increasing their surface hydrophilicity. The effects of treatment parameters, which are irradiating time, pressure and electricity current on characteristics of plasma-treated SWCNHs was investigated and reported. It was found that oxygen plasma treatment enhanced hydrophilic property of SWCNHs. SWCNHs treated by oxygen plasma can be dispersed in deionized water for a long time period when compared with pristine SWCNHs. It is also reasonable to imply the presence of C=O, carboxylic group, on the surface of SWCNHs treated by oxygen plasma treatment would lead to a higher level of their dispersion. In addition, zeta potential analysis could confirm the stability of the plasma-treated SWCNHs. For examining slow releases behavior polyvinylpyrrolidone-iodine (PVPI) was impregnated onto the pristine and plasma-treated SWCNHs. It was found that plasma-treated SWCNHs can help reduce the desorption rate of PVPI, leading to its slow release because of functional groups. The pseudo 2nd order kinetic model could be fitted for estimating PVPI release.
DOI: 10.14457/cu.the.2011.1107
title: Bacterial community in intestine of black tiger shrimp Penaeus monodon

description: The black tiger shrimp Penaeus monodon is an important aquaculture species for Thailand. In recent years, the industry faced with several problems such as a lack of suitable broodstocks, environmental impact, and diseases. Intestinal bacteria of aquatic animals play a crucial role in the host-animals well-being such as improving digestive system and disease resistance, but the understanding of shrimp-bacteria interaction is limited. The objective of this thesis was to examine several aspects of the intestinal bacterial community associated with black tiger shrimp (Penaeus monodon) including (1) the differences in the intestinal bacterial community of farmed juvenile shrimp of different sizes in the same cohort, (2) the diversity of the intestinal bacteria community in different segments of the gastrointestinal tract, and (3) the variation in the intestinal bacterial community upon a challenge with shrimp pathogen Vibrio harveyi. In addition, pure culture isolates collected from the intestines of P. monodon were also screened for inhibitory effects against V. harveyi and V. parahaemolyticus. Bacterial communities from the intestinal tracts of 60 farmed-raised juveniles and 5 different segments of the GI tracts of 8 wild-caught adult shrimps were analyzed using PCR-DGGE, cluster analysis, and 16S rDNA sequencing. The intestinal bacterial communities of P. monodon are a diverse group of bacteria that generally included 3 to 4 main phyla including Proteobacteria (β-, δ-, γ- and α-), Fusobacteria, Firmicutes and Bacteroidetes. Regardless of the source or life-history of the shrimp, γ- Proteobacteria is the most abundant in the intestinal community and can be found in all segments. Other phyla were less abundant and limited to certain segments in their distribution. Vibrio spp. or Photobacterium sp. are dominant genera that can be found in farm-raised juvenile and wild-caught adults. Bacterial communities from farm-raised juvenile shrimp of different sizes showed no distinct clustering pattern by size at either 2 or 5 month. However, the differences in bacterial communities between 2 and 5 month old juveniles were pronounced. Bacterial communities in different segments of the GI tract of wild-caught adults were different in both the diversity and composition. The change in the intestinal bacterial community upon challenge with V. harveyi can usually be observed after 48 hrs. Seventeen pure culture isolates were shown to inhibit the growth of both V. harveyi and V. parahaemolyticus using co-culture methods. Twelve isolates that were selected for further characterization were closely related to Vibrio spp. (8 isolates), Shewanella spp. (2 isolate), Pseudomonas sp. (1 isolate), and Pseudoalteromonas sp. (1 isolate).