cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.14724221
title: Supplementary File – Table S3. The proportion of teleost species with multiple sex chromosome systems to all species with sex chromosomes per order. from Multiple sex chromosomes in teleost fishes from a cytogenetic perspective: state of the art and future challenges

description: Despite decades of cytogenetic and genomic research of dynamic sex chromosome evolution in teleost fishes, multiple sex chromosomes have been largely neglected. In this review, we compiled available data on teleost multiple sex chromosomes, identified major trends in their evolution and suggest further trajectories in their investigation. In a compiled dataset of 440 verified records of fish sex chromosomes, we counted 75 multiple sex chromosome systems with 60 estimated independent origins. We showed that male-heterogametic systems created by Y-autosome fusion predominate and that multiple sex chromosomes are overrepresented in the order Perciformes. We documented a striking difference in patterns of differentiation of sex chromosomes between male and female heterogamety and hypothesize that faster W sex chromosome differentiation may constrain sex chromosome turnover in female-heterogametic systems. We also found no significant association between the mechanism of multiple sex chromosome formation and percentage of uni-armed chromosomes in teleost karyotype. Last but not least, we hypothesized that interaction between fish populations, which differ in their sex chromosomes, can drive the evolution of multiple sex chromosomes in fishes. This underlines the importance of broader inter-population sampling in studies of fish sex chromosomes.This article is part of the theme issue ‘Challenging the paradigm in sex chromosome evolution: empirical and theoretical insights with a focus on vertebrates (Part II)’.
DOI: 10.6084/m9.figshare.14724218
title: Supplementary File – Table S7. Summary of presence of multiple sex chromosomes in Teleostei, probable mechanism of their origin, karyotype composition and estimation of the number of independent origins of multiple sex chromosomes with comment regarding statistical analysis. from Multiple sex chromosomes in teleost fishes from a cytogenetic perspective: state of the art and future challenges

description: Despite decades of cytogenetic and genomic research of dynamic sex chromosome evolution in teleost fishes, multiple sex chromosomes have been largely neglected. In this review, we compiled available data on teleost multiple sex chromosomes, identified major trends in their evolution and suggest further trajectories in their investigation. In a compiled dataset of 440 verified records of fish sex chromosomes, we counted 75 multiple sex chromosome systems with 60 estimated independent origins. We showed that male-heterogametic systems created by Y-autosome fusion predominate and that multiple sex chromosomes are overrepresented in the order Perciformes. We documented a striking difference in patterns of differentiation of sex chromosomes between male and female heterogamety and hypothesize that faster W sex chromosome differentiation may constrain sex chromosome turnover in female-heterogametic systems. We also found no significant association between the mechanism of multiple sex chromosome formation and percentage of uni-armed chromosomes in teleost karyotype. Last but not least, we hypothesized that interaction between fish populations, which differ in their sex chromosomes, can drive the evolution of multiple sex chromosomes in fishes. This underlines the importance of broader inter-population sampling in studies of fish sex chromosomes.This article is part of the theme issue ‘Challenging the paradigm in sex chromosome evolution: empirical and theoretical insights with a focus on vertebrates (Part II)’.
DOI: 10.6084/m9.figshare.14724215
title: Supplementary File – Table S4. Updated list of teleost sex chromosome systems including datasets for evaluation of sex chromosome differentiation and comparison with the Tree of Sex database. from Multiple sex chromosomes in teleost fishes from a cytogenetic perspective: state of the art and future challenges

description: Despite decades of cytogenetic and genomic research of dynamic sex chromosome evolution in teleost fishes, multiple sex chromosomes have been largely neglected. In this review, we compiled available data on teleost multiple sex chromosomes, identified major trends in their evolution and suggest further trajectories in their investigation. In a compiled dataset of 440 verified records of fish sex chromosomes, we counted 75 multiple sex chromosome systems with 60 estimated independent origins. We showed that male-heterogametic systems created by Y-autosome fusion predominate and that multiple sex chromosomes are overrepresented in the order Perciformes. We documented a striking difference in patterns of differentiation of sex chromosomes between male and female heterogamety and hypothesize that faster W sex chromosome differentiation may constrain sex chromosome turnover in female-heterogametic systems. We also found no significant association between the mechanism of multiple sex chromosome formation and percentage of uni-armed chromosomes in teleost karyotype. Last but not least, we hypothesized that interaction between fish populations, which differ in their sex chromosomes, can drive the evolution of multiple sex chromosomes in fishes. This underlines the importance of broader inter-population sampling in studies of fish sex chromosomes.This article is part of the theme issue ‘Challenging the paradigm in sex chromosome evolution: empirical and theoretical insights with a focus on vertebrates (Part II)’.
DOI: 10.6084/m9.figshare.14724209
title: Supplementary File – Table S2. Teleost biodiversity and incidence of multiple sex chromosomes. from Multiple sex chromosomes in teleost fishes from a cytogenetic perspective: state of the art and future challenges

description: Despite decades of cytogenetic and genomic research of dynamic sex chromosome evolution in teleost fishes, multiple sex chromosomes have been largely neglected. In this review, we compiled available data on teleost multiple sex chromosomes, identified major trends in their evolution and suggest further trajectories in their investigation. In a compiled dataset of 440 verified records of fish sex chromosomes, we counted 75 multiple sex chromosome systems with 60 estimated independent origins. We showed that male-heterogametic systems created by Y-autosome fusion predominate and that multiple sex chromosomes are overrepresented in the order Perciformes. We documented a striking difference in patterns of differentiation of sex chromosomes between male and female heterogamety and hypothesize that faster W sex chromosome differentiation may constrain sex chromosome turnover in female-heterogametic systems. We also found no significant association between the mechanism of multiple sex chromosome formation and percentage of uni-armed chromosomes in teleost karyotype. Last but not least, we hypothesized that interaction between fish populations, which differ in their sex chromosomes, can drive the evolution of multiple sex chromosomes in fishes. This underlines the importance of broader inter-population sampling in studies of fish sex chromosomes.This article is part of the theme issue ‘Challenging the paradigm in sex chromosome evolution: empirical and theoretical insights with a focus on vertebrates (Part II)’.
DOI: 10.6084/m9.figshare.14724206
title: Supplementary File – Table S6. Summary of sex chromosomes records in Teleostei based solely on cytogenetic evidence. Cases of multiple sex chromosomes are highlighted. from Multiple sex chromosomes in teleost fishes from a cytogenetic perspective: state of the art and future challenges

description: Despite decades of cytogenetic and genomic research of dynamic sex chromosome evolution in teleost fishes, multiple sex chromosomes have been largely neglected. In this review, we compiled available data on teleost multiple sex chromosomes, identified major trends in their evolution and suggest further trajectories in their investigation. In a compiled dataset of 440 verified records of fish sex chromosomes, we counted 75 multiple sex chromosome systems with 60 estimated independent origins. We showed that male-heterogametic systems created by Y-autosome fusion predominate and that multiple sex chromosomes are overrepresented in the order Perciformes. We documented a striking difference in patterns of differentiation of sex chromosomes between male and female heterogamety and hypothesize that faster W sex chromosome differentiation may constrain sex chromosome turnover in female-heterogametic systems. We also found no significant association between the mechanism of multiple sex chromosome formation and percentage of uni-armed chromosomes in teleost karyotype. Last but not least, we hypothesized that interaction between fish populations, which differ in their sex chromosomes, can drive the evolution of multiple sex chromosomes in fishes. This underlines the importance of broader inter-population sampling in studies of fish sex chromosomes.This article is part of the theme issue ‘Challenging the paradigm in sex chromosome evolution: empirical and theoretical insights with a focus on vertebrates (Part II)’.
DOI: 10.6084/m9.figshare.14724438
title: Datasets for Plio-Pleistocene Establishment of Irtysh River in Junggar.pdf

description: Table S1 is a dataset of neon isotope analyses, which were carried out on a MAP-215 Magnetic Sector Mass Spectrometer at the Scottish Universities Environmental Research Center (SUERC) and on a GV 5400 Noble Gas Mass Spectrometer at the Institute of Geology, China Earthquake Administration (IGCEA). Table S2 is a dataset of Al and Be analyses, in which the <sup>10</sup>Be/<sup>9</sup>Be and <sup>26</sup>Al/<sup>27</sup>Al ratios in the sample and chemical procedural blanks were measured by 5 MV accelerator mass spectrometry (AMS) at SUERC.
DOI: 10.6084/m9.figshare.14724438.v1
title: Datasets for Plio-Pleistocene Establishment of Irtysh River in Junggar.pdf

description: Table S1 is a dataset of neon isotope analyses, which were carried out on a MAP-215 Magnetic Sector Mass Spectrometer at the Scottish Universities Environmental Research Center (SUERC) and on a GV 5400 Noble Gas Mass Spectrometer at the Institute of Geology, China Earthquake Administration (IGCEA). Table S2 is a dataset of Al and Be analyses, in which the <sup>10</sup>Be/<sup>9</sup>Be and <sup>26</sup>Al/<sup>27</sup>Al ratios in the sample and chemical procedural blanks were measured by 5 MV accelerator mass spectrometry (AMS) at SUERC.
DOI: 10.5281/zenodo.4896487
title: V4Design/Europeana style dataset

description: V4Design is a project focused on developing digital tools for art and architecture. The painting styles dataset aims to provide training data for building a deep learning model that classifies paintings in different styles - "aesthetics'' in the V4Design terminology. The motivation for building this model is to allow non expert audiences to retrieve visual works and information about them. <br> The current dataset contains 1614 paintings belonging to the categories Baroque, Rococo, and Other. The images were obtained using the Europeana Search API, selecting open objects from the art thematic collection. 24k images were obtained, from which the current dataset was derived. The labels were added by the V4Design team, using a custom annotation tool. As described in the project documentation, other categories were used besides Baroque and Rococo. But for the sake of training a machine learning model we have retained only the categories with a significant number of annotations. The images can be downloaded using the URL, and more details about the objects (including their provenance) can be found by the Europeana ID and the URI that provide access to the object page at Europeana. These identifiers can be also used to obtain further information in machine-readable ways by using the Europeana Record API. Find more information about the V4Design project and the dataset in the deliverable 2.4 and the V4Design website. More information about Europeana APIs can be found here.
DOI: 10.5281/zenodo.4896486
title: V4Design/Europeana style dataset

description: V4Design is a project focused on developing digital tools for art and architecture. The painting styles dataset aims to provide training data for building a deep learning model that classifies paintings in different styles - "aesthetics'' in the V4Design terminology. The motivation for building this model is to allow non expert audiences to retrieve visual works and information about them. <br> The current dataset contains 1614 paintings belonging to the categories Baroque, Rococo, and Other. The images were obtained using the Europeana Search API, selecting open objects from the art thematic collection. 24k images were obtained, from which the current dataset was derived. The labels were added by the V4Design team, using a custom annotation tool. As described in the project documentation, other categories were used besides Baroque and Rococo. But for the sake of training a machine learning model we have retained only the categories with a significant number of annotations. The images can be downloaded using the URL, and more details about the objects (including their provenance) can be found by the Europeana ID and the URI that provide access to the object page at Europeana. These identifiers can be also used to obtain further information in machine-readable ways by using the Europeana Record API. Find more information about the V4Design project and the dataset in the deliverable 2.4 and the V4Design website. More information about Europeana APIs can be found here.
DOI: 10.5281/zenodo.4897005
title: TRPM4 is highly expressed in human colorectal tumor buds and contributes to proliferation, cell cycle, and invasion of colorectal cancer cells

description: Transient receptor potential melastatin-4 channel (TRPM4) dysregulation contributes to heart conditions, immune diseases, and cervical and prostate cancer. Up to now, the involvement of TRPM4 in colorectal cancer (CRC) pathophysiology remains unknown. Here, we investigated tumor tissue microarrays from 379 CRC patients and analyzed TRPM4 protein expression, tumor characteristics, and clinical outcome. High TRPM4 protein expression was associated with unfavorable tumor features characteristic for epithelial-mesenchymal transition and infiltrative growth patterns, that is, a high number of tumor buds and a low percentage in tumor border configuration. Compared to CRC cells representing early cancer stages, TRPM4 protein expression was the highest in cells representing late-stage metastatic cancer. Investigation of CRC cell line HCT116 and five CRISPR/cas9 TRPM4 knockout clones demonstrated that TRPM4 exhibited large Na<sup>+</sup> current densities (~ 60 pA/pF). In addition, CRISPR/cas9 TRPM4 knockout clones showed a tendency toward decreased migration and invasion, cell viability, and proliferation and exhibited a shift in cell cycle when compared to HCT116. Stable overexpression of TRPM4 (TRPM4 wild-type) in two CRISPR/cas9 TRPM4 knockout clones rescued the decrease in cell viability and cell cycle shift. Stable overexpression of a nonconducting, dominant-negative TRPM4 mutant (TRPM4 D894A) did not rescue the decrease in viability or cell cycle shift. Taken together, these findings pointed to TRPM4 ion channel conductivity as the underlying mechanism for decreased viability and cell cycle shift in the TRPM4 knockout clones. Together with previous findings, our present data suggest that TRPM4 plays a versatile role in cancer cell proliferation, cell cycle, and invasion.
DOI: 10.6084/m9.figshare.13633943.v2
title: Copy number variants in Nubian ibex

description: Copy number variants detected in Nubian genome using read depth and split read method.
DOI: 10.5281/zenodo.4897004
title: TRPM4 is highly expressed in human colorectal tumor buds and contributes to proliferation, cell cycle, and invasion of colorectal cancer cells

description: Transient receptor potential melastatin-4 channel (TRPM4) dysregulation contributes to heart conditions, immune diseases, and cervical and prostate cancer. Up to now, the involvement of TRPM4 in colorectal cancer (CRC) pathophysiology remains unknown. Here, we investigated tumor tissue microarrays from 379 CRC patients and analyzed TRPM4 protein expression, tumor characteristics, and clinical outcome. High TRPM4 protein expression was associated with unfavorable tumor features characteristic for epithelial-mesenchymal transition and infiltrative growth patterns, that is, a high number of tumor buds and a low percentage in tumor border configuration. Compared to CRC cells representing early cancer stages, TRPM4 protein expression was the highest in cells representing late-stage metastatic cancer. Investigation of CRC cell line HCT116 and five CRISPR/cas9 TRPM4 knockout clones demonstrated that TRPM4 exhibited large Na<sup>+</sup> current densities (~ 60 pA/pF). In addition, CRISPR/cas9 TRPM4 knockout clones showed a tendency toward decreased migration and invasion, cell viability, and proliferation and exhibited a shift in cell cycle when compared to HCT116. Stable overexpression of TRPM4 (TRPM4 wild-type) in two CRISPR/cas9 TRPM4 knockout clones rescued the decrease in cell viability and cell cycle shift. Stable overexpression of a nonconducting, dominant-negative TRPM4 mutant (TRPM4 D894A) did not rescue the decrease in viability or cell cycle shift. Taken together, these findings pointed to TRPM4 ion channel conductivity as the underlying mechanism for decreased viability and cell cycle shift in the TRPM4 knockout clones. Together with previous findings, our present data suggest that TRPM4 plays a versatile role in cancer cell proliferation, cell cycle, and invasion.
DOI: 10.34740/kaggle/dsv/2299501
title: 2021 World Population (updated daily)
DOI: 10.6084/m9.figshare.14724516
title: Supplementary Material for: Plasma Xanthine Oxidoreductase Activity Associated with Glycemic Control in Patients with Pre-Dialysis Chronic Kidney Disease

description: <b><i>Introduction:</i></b> Xanthine oxidoreductase (XOR) activity plays an important role as a pivotal source of reactive oxygen species, which is associated with cardiovascular disease (CVD) events. Patients with CKD have increased risk of CVD events. In the present study, factors associated with plasma XOR activity in pre-dialysis CKD patients were investigated. <b><i>Methods:</i></b> In this cross-sectional study, plasma XOR activity in 118 pre-dialysis CKD patients (age 68 [57–75] years; 64 males, 26 with diabetes mellitus [DM]) was determined using a newly established highly sensitive assay based on (<sup>13</sup>C<sub>2</sub>,<sup>15</sup>N<sub>2</sub>) xanthine and liquid chromatography/triple quadrupole mass spectrometry. <b><i>Results:</i></b> Plasma glucose, hemoglobin A1c, and estimated glomerular filtration (eGFR) were significantly and positively correlated with plasma logarithmically transformed XOR (ln-XOR) activity. In multiple regression analyses, eGFR and hemoglobin A1c or plasma glucose were significantly, independently, and positively associated with plasma ln-XOR activity after adjusting for several confounders. Plasma XOR activity was significantly higher in CKD patients with (<i>n</i> = 26) than in those without (<i>n</i> = 92) DM (62.7 [32.3–122] vs. 25.7 [13.4–45.8] pmol/h/mL, <i>p</i> &lt; 0.001). A total of 38 patients were taking uric acid-lowering drugs. Multiple regression analysis of CKD patients not administered uric acid-lowering drugs (<i>n</i> = 80) showed no significant association between eGFR and plasma ln-XOR activity. In contrast, association between glycemic control and plasma ln-XOR activity was significant even in CKD patients without uric acid-lowering drug treatment. <b><i>Conclusions:</i></b> These results indicate the importance of glycemic control in CKD patients in regard to decreased XOR, possibly leading to a decrease in CVD events.
DOI: 10.34740/kaggle/dsv/2299527
title: YouTube Trending Video Dataset (updated daily)
DOI: 10.5281/zenodo.4897072
title: Groundwater flow rate prediction from geo-electrical features using Support Vector Machines: Bagoue dataset, Cote d'Ivoire

description: We implemented a support vector machines to predict groundwater flow before drilling using electrical resistivity profiling, vertical electrical sounding. We used the data from Cote d’Ivoire, west part of Africa and we tested the composite estimator in region of Bagoue, north part of CIV. Data are composed on electrical resistivity profile, vertical electrical sounding and borehole data. The coordinates of different boreholes are also mentioned.
DOI: 10.3886/e139461v4
title: Messaging to boost COVID-19 vaccinations: emphasize personal health benefits

description: The rapid development of COVID-19 vaccines is a tremendous scientific response to the current global pandemic. However, vaccines per se do not save lives and restart economies. The success of the vaccines depends on the number of people getting vaccinated. We use a survey experiment to examine the impact on vaccine intentions of a variety of public health messages identified as particularly promising: three messages that emphasize different benefits from the vaccines (personal health, the health of others, and the recovery of local and national economies), and one message that emphasizes vaccine safety. Because people will likely be exposed to multiple messages in the real world, we also examine the effect of these messages in combinations. Based on a nationally quota representative sample of 3,048 adults in the United States, our findings suggest that several forms of public messages can increase vaccine intentions, but messaging that emphasizes personal health benefits had the largest impact.
DOI: 10.5281/zenodo.4864599
title: Oracle Blockchain extraction depuis Google scholar

description: Ces données sont une extractions de Google scholar. Le but de cette extraction est d'effectuer des tendances par rapport aux citations et publications parlant des oracles et de la Blockchain.
DOI: 10.5281/zenodo.4864598
title: Oracle Blockchain extraction depuis Google scholar

description: Ces données sont une extractions de Google scholar. Le but de cette extraction est d'effectuer des tendances par rapport aux citations et publications parlant des oracles et de la Blockchain.
DOI: 10.6084/m9.figshare.12611786
title: Data for single-locus and haplotype-based GWAS

description: Data for single-locus and haplotype-based GWAS
DOI: 10.6084/m9.figshare.12611786.v1
title: Data for single-locus and haplotype-based GWAS

description: Data for single-locus and haplotype-based GWAS