cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17630/ec95b62c-ab3e-4331-9c1d-f6af1ab69f12
title: Data underpinning - "Analysis of the Precision, Robustness and Speed of Elastic Resonator Interference Stress Microscopy"

description: 05.05.2017 St Andrews, Philipp Liehm

Requirements:

1. Install the python package Anaconda 2.3 (not tested with other versions, likely to work with newer versions as well)
https://www.continuum.io/downloads

2. To run ERISM_Calc_3.0.py you need to have a compiled version of the additional cython package. (cython_all_fit.pyx --&gt; compile --&gt;cython_all_fit.pyd)

3. To compile under WINDOWS you need the setup_normal_win7.py and run from the command line:
"python setup_normal_win7.py build_ext --inplace"
You may be required to install the free C++ Compiler for Python 2.7:
http://aka.ms/vcpython27
DOI: 10.6084/m9.figshare.24671508
title: Supplementary Material for: Cone-beam CT-guided cryobiopsy combined with conventional biopsy for GGO-predominant pulmonary nodules

description: Introduction: Cryobiopsy (CB) using a 1.1-mm cryoprobe under fluoroscopic guidance is feasible and safe for diagnosis of ground glass opacity (GGO) lesions. However, the efficacy of CB combined with cone-beam CT (CBCT) for GGO-predominant pulmonary nodules remains elusive. Methods: We retrospectively studied patients who underwent CB combined with conventional biopsy under CBCT guidance for GGO-predominant pulmonary nodules with a consolidation to tumour ratio &lt;50.0%. Results: A total of 32 patients with GGO-predominant pulmonary nodules were enrolled: 17 pure GGOs and 15 mixed GGOs. The mean lesion diameter was 15.81±5.52 mm and the overall diagnostic yield was 71.9%. Seven lesions were diagnosed by CB alone, which increased the diagnostic outcomes by 21.9%. Diagnostic yields for CB, forceps biopsy (FB), brushing and guide sheath flushing were 65.6%, 46.9%, 15.6% and 14.3%, respectively. Univariate analysis revealed that positive CT bronchus sign (P = 0.035), positive CBCT sign (P &lt; 0.01) and CB-first biopsy sequence (P = 0.036) were significant predictive factors for higher diagnostic yield. Specimens obtained by CB had larger mean sample size (P &lt; 0.01), lower blood cell area (P &lt; 0.01) and fewer crush artefacts (P &lt; 0.01) than specimens from FB. No severe bleeding or other complications occurred. Conclusion: Cryobiopsy using a 1.1-mm cryoprobe under cone-beam CT guidance increased diagnostic yield for GGO-predominant pulmonary nodules based on conventional biopsy. Further, it provided larger and nearly intact samples compared with forceps.
DOI: 10.6084/m9.figshare.24671508.v1
title: Supplementary Material for: Cone-beam CT-guided cryobiopsy combined with conventional biopsy for GGO-predominant pulmonary nodules

description: Introduction: Cryobiopsy (CB) using a 1.1-mm cryoprobe under fluoroscopic guidance is feasible and safe for diagnosis of ground glass opacity (GGO) lesions. However, the efficacy of CB combined with cone-beam CT (CBCT) for GGO-predominant pulmonary nodules remains elusive. Methods: We retrospectively studied patients who underwent CB combined with conventional biopsy under CBCT guidance for GGO-predominant pulmonary nodules with a consolidation to tumour ratio &lt;50.0%. Results: A total of 32 patients with GGO-predominant pulmonary nodules were enrolled: 17 pure GGOs and 15 mixed GGOs. The mean lesion diameter was 15.81±5.52 mm and the overall diagnostic yield was 71.9%. Seven lesions were diagnosed by CB alone, which increased the diagnostic outcomes by 21.9%. Diagnostic yields for CB, forceps biopsy (FB), brushing and guide sheath flushing were 65.6%, 46.9%, 15.6% and 14.3%, respectively. Univariate analysis revealed that positive CT bronchus sign (P = 0.035), positive CBCT sign (P &lt; 0.01) and CB-first biopsy sequence (P = 0.036) were significant predictive factors for higher diagnostic yield. Specimens obtained by CB had larger mean sample size (P &lt; 0.01), lower blood cell area (P &lt; 0.01) and fewer crush artefacts (P &lt; 0.01) than specimens from FB. No severe bleeding or other complications occurred. Conclusion: Cryobiopsy using a 1.1-mm cryoprobe under cone-beam CT guidance increased diagnostic yield for GGO-predominant pulmonary nodules based on conventional biopsy. Further, it provided larger and nearly intact samples compared with forceps.
DOI: 10.6084/m9.figshare.24511399
title: Supplementary Material for: Effects of Breast-Conserving Surgery and Mastectomy on the Survival of Patients with Early-stage (T1-2N0-1M0) HER2-Positive Breast Cancer: A Propensity Score-Matched Analysis

description: Introduction: Although breast-conserving therapy (BCT) promises at least a similar survival rate for patients with early breast cancer compared with mastectomy, its efficacy in patients with human epidermal growth factor receptor 2 (HER2)-positive tumors remains unclear. Therefore, we conducted this study to explore differential effects of BCT and mastectomy on survival outcomes of patients with early-stage HER2-positive breast cancer. Methods: Data were extracted from the Surveillance, Epidemiology, and End Results (SEER) database, and basic characteristics of patients who received either BCT or mastectomy were balanced using propensity score matching (PSM). Kaplan-Meier analysis, log-rank testing, and Cox proportional hazards regression were performed. Results: In total, 20,277 patients were diagnosed with T1-2N0-1M0 HER2-positive breast cancer between 2010 and 2015. After PSM, 6,185 pairs of patients were enrolled for further analysis. Compared with those undergoing mastectomy, patients receiving BCT had superior overall survival (OS) (hazard ratio [HR], 0.63; 95% confidence interval [CI]: 0.55–0.73; P &lt; 0.001) and breast cancer-specific survival (BCSS) (HR: 0.59; 95% CI: 0.48–0.71; P &lt; 0.001). The subgroup analyses revealed that survival outcomes (OS and BCSS) of BCT were better than that of mastectomy among estrogen receptor (ER)+/progesterone receptor (PR)+/HER2+, ER+/PR-/HER2+, and ER-/PR-/HER2+subtypes (P &lt; 0.05 for all); however, patients with ER-/PR+/HER2+ subtypes who underwent BCT had similar OS and BCSS (P &gt; 0.05 for both) to those treated with mastectomy. Discussion/Conclusion: Despite the aggressiveness of the disease, we found that BCT may confer a better long-term survival than mastectomy for patients with T1-2N0-1M0 HER2-positive breast cancer, particularly for those with ER+/PR+/HER2+, ER+/PR-/HER2+, and ER-/PR-/HER2+ subtypes. In addition, our study provided insights into the clinical applications of BCT. However, this retrospective study has introduced several inevitable limitations, and further prospective research is warranted to verify these conclusions.
DOI: 10.6084/m9.figshare.24511399.v1
title: Supplementary Material for: Effects of Breast-Conserving Surgery and Mastectomy on the Survival of Patients with Early-stage (T1-2N0-1M0) HER2-Positive Breast Cancer: A Propensity Score-Matched Analysis

description: Introduction: Although breast-conserving therapy (BCT) promises at least a similar survival rate for patients with early breast cancer compared with mastectomy, its efficacy in patients with human epidermal growth factor receptor 2 (HER2)-positive tumors remains unclear. Therefore, we conducted this study to explore differential effects of BCT and mastectomy on survival outcomes of patients with early-stage HER2-positive breast cancer. Methods: Data were extracted from the Surveillance, Epidemiology, and End Results (SEER) database, and basic characteristics of patients who received either BCT or mastectomy were balanced using propensity score matching (PSM). Kaplan-Meier analysis, log-rank testing, and Cox proportional hazards regression were performed. Results: In total, 20,277 patients were diagnosed with T1-2N0-1M0 HER2-positive breast cancer between 2010 and 2015. After PSM, 6,185 pairs of patients were enrolled for further analysis. Compared with those undergoing mastectomy, patients receiving BCT had superior overall survival (OS) (hazard ratio [HR], 0.63; 95% confidence interval [CI]: 0.55–0.73; P &lt; 0.001) and breast cancer-specific survival (BCSS) (HR: 0.59; 95% CI: 0.48–0.71; P &lt; 0.001). The subgroup analyses revealed that survival outcomes (OS and BCSS) of BCT were better than that of mastectomy among estrogen receptor (ER)+/progesterone receptor (PR)+/HER2+, ER+/PR-/HER2+, and ER-/PR-/HER2+subtypes (P &lt; 0.05 for all); however, patients with ER-/PR+/HER2+ subtypes who underwent BCT had similar OS and BCSS (P &gt; 0.05 for both) to those treated with mastectomy. Discussion/Conclusion: Despite the aggressiveness of the disease, we found that BCT may confer a better long-term survival than mastectomy for patients with T1-2N0-1M0 HER2-positive breast cancer, particularly for those with ER+/PR+/HER2+, ER+/PR-/HER2+, and ER-/PR-/HER2+ subtypes. In addition, our study provided insights into the clinical applications of BCT. However, this retrospective study has introduced several inevitable limitations, and further prospective research is warranted to verify these conclusions.
DOI: 10.17630/b2ccc0c6-5a00-420e-92d4-d4d64173d259
title: Chiral Iridium(III) and Ruthenium(II) Complexes as Phosphorescent Scaffolds for Heterometallic Supramolecular Self-Assembly_Thesis Data

description: These files contain all data outputs that are foundation of my Ph.D. tesis. The files have been divided according to the five experimental chapters reported in my thesis. Chapter 2: enantiopure iridium complexes for LEECs, chapter 3: supramolecular Ir(III) and Ru(II) cages, chapter 4: supramolecular Ir-ZnTPP and Ru-ZnTPP assemblies and chapter 5: luminescent Ir-Ag polymer.

The data files are embargoed until 31/05/2019.
DOI: 10.6084/m9.figshare.24560158.v1
title: Supplementary Material for: Clinical features, treatment modalities and outcomes of elderly thymoma patients: A propensity–matched study based on the SEER database

description: Introduction: Thymoma is a common mediastinal tumor, but few studies have been performed in thymoma patients 80 years or older. This study aimed to analyze the clinical features, treatment modalities and survival outcomes of thymoma patients at least 80 years old and compare these features to those of patients younger than 80 years old. Method: Data from thymoma patients in the Surveillance, Epidemiology and End Results database between 2000 and 2019 were selected. Clinical features, treatment modalities of the two age groups were compared. Survival rates were calculated by the Kaplan-Meier method and the log-rank test was used to compare survival rates between two groups. Propensity score matching was used based on whether surgery was performed. Univariate and multivariate Cox proportional–hazards regression analyses were performed to identify independent prognostic factors. Results: Compared with the younger patients, the patients aged 80 years or older had a similar distribution of Masaoka–Koga tumor stage, a higher proportion of type A thymoma, and a lower recurrence rate in the early stage. In elderly patients after propensity score matching, the overall survival and cancer–specific survival were better in the surgery group with complete resection and similar benefit from surgery as younger patients were observed. Conclusion: In thymoma patients aged 80 years or older, surgery still plays an important role in survival outcome. Compared with younger patients, older patients had unique clinical features.
DOI: 10.6084/m9.figshare.24560158
title: Supplementary Material for: Clinical features, treatment modalities and outcomes of elderly thymoma patients: A propensity–matched study based on the SEER database

description: Introduction: Thymoma is a common mediastinal tumor, but few studies have been performed in thymoma patients 80 years or older. This study aimed to analyze the clinical features, treatment modalities and survival outcomes of thymoma patients at least 80 years old and compare these features to those of patients younger than 80 years old. Method: Data from thymoma patients in the Surveillance, Epidemiology and End Results database between 2000 and 2019 were selected. Clinical features, treatment modalities of the two age groups were compared. Survival rates were calculated by the Kaplan-Meier method and the log-rank test was used to compare survival rates between two groups. Propensity score matching was used based on whether surgery was performed. Univariate and multivariate Cox proportional–hazards regression analyses were performed to identify independent prognostic factors. Results: Compared with the younger patients, the patients aged 80 years or older had a similar distribution of Masaoka–Koga tumor stage, a higher proportion of type A thymoma, and a lower recurrence rate in the early stage. In elderly patients after propensity score matching, the overall survival and cancer–specific survival were better in the surgery group with complete resection and similar benefit from surgery as younger patients were observed. Conclusion: In thymoma patients aged 80 years or older, surgery still plays an important role in survival outcome. Compared with younger patients, older patients had unique clinical features.
DOI: 10.17630/255feac7-f9e5-4690-a351-87be9842b266
title: Data underpinning - Isolation of EPR spectra and estimation of spin-states in two-component mixtures of paramagnets
DOI: 10.6084/m9.figshare.24523345
title: Supplementary Material for: Immunothrombosis and complement activation contribute to disease severity and adverse outcome in COVID-19

description: Severe COVID-19 is characterized by systemic inflammation and multiple organ dysfunction syndrome (MODS). Arterial and venous thrombosis are involved in the pathogenesis of MODS and fatality in COVID-19. There is evidence that complement - and neutrophil activation in the form of neutrophil extracellular traps are main drivers for development of microvascular complications in COVID-19. Plasma and serum samples were collected from 83 patients infected by SARS-CoV-2 during the two first waves of COVID-19, before the availability of SARS-CoV-2 vaccination. Samples were collected at enrollment, day 11, and day 28; and patients had differing severity of disease. In this comprehensive study, we measured cell-free DNA, neutrophil activation, deoxyribonuclease 1 activity, complement activation, and D-dimers in longitudinal samples of COVID-19 patients. We show that all the above markers, except deoxyribonuclease 1 activity, increased with disease severity. Moreover, we provide evidence that in severe disease there is continued neutrophil and complement activation, as well as D-dimer formation and nucleosome release, whereas in mild and moderate disease all these markers decrease over time. These findings suggest that neutrophil and complement activation are important drivers of microvascular complications and that they reflect immunothrombosis in these patients. Neutrophil activation, complement activation, cell-free DNA and D-dimer levels have the potential to serve as reliable biomarkers for disease severity and fatality in COVID-19. They might also serve as suitable markers with which to monitor the efficacy of therapeutic interventions in COVID-19.
DOI: 10.17630/0d90f281-6448-46ae-8b29-1d2d4ca2dbe8
title: Learning to focus and focusing to learn: more than a cortical trick (Thesis data)

description: Attentional set-shifting data have been transcribed into SPSS files, detailing trials and errors to criterion for all experimental chapters. Histological images are provided for experiments with surgery, and are either .jpeg or .tiff files. The data files are embargoed until 05/09/2023.
DOI: 10.17630/663d8f1b-842c-41d5-b03b-8d5ebbf883f1
title: Data underpinning - Nitroxide-nitroxide and nitroxide-metal distance measurements in transition metal complexes with two or three paramagnetic centres give access to thermodynamic and kinetic stabilities
DOI: 10.17630/be25b3ca-49e0-421f-9fb2-8f75f4bb4202
title: Data underpinning - "Flexible and Ultra-lightweight Polymer Membrane Lasers"

description: Data for each figure panel from the paper that displays numerical data are provided in the form of ASCII text-formatted data (.txt).
DOI: 10.6084/m9.figshare.24586431
title: Supplementary Material for: Human Ribonuclease 6 has a Protective Role During Experimental Urinary Tract Infection

description: Mounting evidence suggests that antimicrobial peptides and proteins (AMPs) belonging to the RNase A superfamily have a critical role in defending the bladder and kidney from bacterial infection. RNase 6 has been identified as a potent, leukocyte-derived AMP, but its impact on urinary tract infection (UTI) in vivo has not been demonstrated. To test the functional role of human RNase 6, we generated RNASE6 transgenic mice and studied their susceptibility to experimental UTI. In addition, we generated bone marrow derived macrophages to study the impact of RNase 6 on antimicrobial activity within a cellular context. When subjected to experimental UTI, RNASE6 transgenic mice developed reduced UPEC burden, mucosal injury, and inflammation compared to non-transgenic controls. Monocytes and macrophages were the predominant cellular sources of RNase 6 during UTI, and RNASE6 transgenic macrophages were more proficient at intracellular UPEC killing than non-transgenic controls. Altogether, our findings indicate a protective role for human RNase 6 during experimental UTI.
DOI: 10.5281/zenodo.10257618
title: Software Development Waste amidst COVID-19 Pandemic: An Industry Study

description: The dataset is to support the publication "Software Development Waste amidst COVID-19 Pandemic: An Industry Study" in ISEC 2024.
DOI: 10.17630/b70593fb-53b6-4963-b1f8-d69ba977260b
title: Phosphorescent Cationic Iridium(III) Complexes Bearing a Nonconjugated Six- Membered Chelating Ancillary Ligand: A Strategy for Tuning the Emission Towards the Blue (dataset)
DOI: 10.17630/2dec867e-570d-4bcc-99ba-2cefe7479357
title: data underpinning "Multiple roles of aryloxide leaving groups in enantioselective annulations employing  a,b-unsaturated acyl ammonium catalysis"

description: data underpinning "Multiple roles of aryloxide leaving groups in enantioselective annulations employing  a,b-unsaturated acyl ammonium catalysis
DOI: 10.17630/29308cf7-b6b6-4b1b-809b-a12fe91b250f
title: Data underpinning - Manganese catalyzed hydrogenation of enantiomerically pure esters

description: 1) NMR files for starting material and products. Needs the use of MestReNova  or similar software. 2) Pdf of raw analytical data from chiral HPLC. 3) chemdraw files. 4) supplementary information pdf
DOI: 10.5519/qd.86gllf3h
title: Query on the Natural History Museum Data Portal (data.nhm.ac.uk) (99963 records)
DOI: 10.17630/b641a08a-a98c-4bbc-a1f6-5cadcbb69cc8
title: Synthesis, Characterisation and Optoelectronic Properties of Phosphorescent Iridium Complexes: from five to six-membered ring chelates. (thesis data)

description: The data files are embargoed until 30/07/2019 (included).
DOI: 10.25375/uct.24633867
title: Western Cape (excl City of Cape Town) Social Vulnerability Indicator results (Prototype 2)

description: Results from Social Vulnerability Indicators analysis. Reported on in: https://doi.org/10.25375/uct.24376036 Based on publicly available South African 2011 Census data. Available from - http://nesstar.statssa.gov.za:8282/webview/
DOI: 10.25375/uct.24633867.v1
title: Western Cape (excl City of Cape Town) Social Vulnerability Indicator results (Prototype 2)

description: Results from Social Vulnerability Indicators analysis. Reported on in: https://doi.org/10.25375/uct.24376036 Based on publicly available South African 2011 Census data. Available from - http://nesstar.statssa.gov.za:8282/webview/
DOI: 10.5281/zenodo.10276573
title: DEM of the Bossons glacier (30 May 2023)

description: DEM of the Bossons glacier in the vicinity of the lake measured the 30 May 2023 by Latitude Drone (Arnaud STEPHAN)
Format:x, y (meters Lambert 2 or Lambert 93) and z ((meters NGF IGN 69) for the glacier DEM (mnt_bossons)orthophoto in Lambert 2 and NGF IGN 69
DOI: 10.5281/zenodo.10276572
title: DEM of the Bossons glacier (30 May 2023)

description: DEM of the Bossons glacier in the vicinity of the lake measured the 30 May 2023 by Latitude Drone (Arnaud STEPHAN)
Format:x, y (meters Lambert 2 or Lambert 93) and z ((meters NGF IGN 69) for the glacier DEM (mnt_bossons)orthophoto in Lambert 2 and NGF IGN 69
DOI: 10.5281/zenodo.10276437
title: Contour of the Bossons lake at different dates in 2021, 2022 and 2023

description: Each file contains the contour points X and Y of the Bossons Lake (French Alps) in Lambert II
DOI: 10.5281/zenodo.10276436
title: Contour of the Bossons lake at different dates in 2021, 2022 and 2023

description: Each file contains the contour points X and Y of the Bossons Lake (French Alps) in Lambert II
DOI: 10.5517/ccdc.csd.cc2bcfsy
title: CCDC 2155950: Experimental Crystal Structure Determination

description: Related Article: Zongli Xiong, Fuxing Xu, Yuqiao Zhou, Rong Zhang, Yulong Zhang, Yushuang Chen, Weijun Yao, Zhen Wang|2023|Org.Lett.|25|8302|doi:10.1021/acs.orglett.3c03378
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2dgl5n
title: CCDC 2218551: Experimental Crystal Structure Determination

description: Related Article: Zongli Xiong, Fuxing Xu, Yuqiao Zhou, Rong Zhang, Yulong Zhang, Yushuang Chen, Weijun Yao, Zhen Wang|2023|Org.Lett.|25|8302|doi:10.1021/acs.orglett.3c03378
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2ggwc6
title: CCDC 2278418: Experimental Crystal Structure Determination

description: Related Article: Zongli Xiong, Fuxing Xu, Yuqiao Zhou, Rong Zhang, Yulong Zhang, Yushuang Chen, Weijun Yao, Zhen Wang|2023|Org.Lett.|25|8302|doi:10.1021/acs.orglett.3c03378
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2gl4jr
title: CCDC 2281554: Experimental Crystal Structure Determination

description: Related Article: Shalene N. Bothma, Charles J. Sheppard, Mark M. Turnbull, Christopher P. Landee, Melanie Rademeyer|2023|CrystEngComm|25|6568|doi:10.1039/D3CE00855J
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2gl4ks
title: CCDC 2281555: Experimental Crystal Structure Determination

description: Related Article: Shalene N. Bothma, Charles J. Sheppard, Mark M. Turnbull, Christopher P. Landee, Melanie Rademeyer|2023|CrystEngComm|25|6568|doi:10.1039/D3CE00855J
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.