cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q2v1257p
title: BindingDB Entry 50034037: 5-(2'-Pyridyl)-2-aminothiazoles: alkyl amino sulfonamides and sulfamides as potent NPY(5) antagonists.

description: Small molecule binding data for protein Cytochrome P450 1A, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), Cytochrome P450 3A, NPY5R, and Neuropeptide Y receptor type 5 ( NPY Y5), Uniprot P05177, P08684, P10635, P11712, P33261, Q15761, and Q63634
DOI: 10.7270/q2vt1sb1
title: BindingDB Entry 50032360: Amino derivatives of indole as potent inhibitors of isoprenylcysteine carboxyl methyltransferase.

description: Small molecule binding data for protein Isoprenylcysteine carboxyl methyltransferase, Uniprot O60725
DOI: 10.7270/q2w37wnn
title: BindingDB Entry 50033172: Substituted phenyl triazoles as selective inhibitors of 11ß-Hydroxysteroid Dehydrogenase Type 1.

description: Small molecule binding data for protein 11-beta-Hydroxysteroid Dehydrogenase 2 (11-beta-HSD2), 11-beta-hydroxysteroid dehydrogenase 1, 11-beta-hydroxysteroid dehydrogenase 2, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), Cytochrome P450 3A, and Pregnane X receptor (PXR), Uniprot O75469, P08684, P10635, P11712, P28845, P50172, P51661, and P80365
DOI: 10.7270/q2zg6scv
title: BindingDB Entry 50031391: Synthesis of potent BACE-1 inhibitors incorporating a hydroxyethylene isostere as central core.

description: Small molecule binding data for protein Beta-secretase 1 and Cathepsin D, Uniprot P07339 and P56817
DOI: 10.7270/q2zk5gq8
title: BindingDB Entry 50030412: Synthetic staurosporines via a ring closing metathesis strategy as potent JAK3 inhibitors and modulators of allergic responses.

description: Small molecule binding data for protein JAK3/JAK1, MAP kinase-activated protein kinase 2, SRC, Transcription factor STAT5a (STAT5a), Tyrosine-protein kinase SYK, and Tyrosine-protein kinase ZAP-70, Uniprot P06239, P42229, P43403, P43405, P49137, and P52333
DOI: 10.7270/q2zs2wxv
title: BindingDB Entry 50034036: Exploiting the lipoic acid structure in the search for novel multitarget ligands against Alzheimer's disease.

description: Small molecule binding data for protein Acetylcholinesterase and Cholinesterase, Uniprot P06276 and P22303
DOI: 10.7270/q21836mc
title: BindingDB Entry 50031408: 2-Aminothiadiazole inhibitors of AKT1 as potential cancer therapeutics.

description: Small molecule binding data for protein AKT/p21CIP1, Cyclin-dependent kinase 2, and Serine/threonine-protein kinase Sgk1, Uniprot O00141, P24941, and P31749
DOI: 10.7270/q21g0m97
title: BindingDB Entry 50030428: Optimization of a series of 2,4-diaminopyridines as neuropeptide Y Y1 receptor antagonists with reduced hERG activity.

description: Small molecule binding data for protein Neuropeptide Y receptor type 1 and Voltage-gated potassium channel, Uniprot P25929 and Q12809
DOI: 10.7270/q21j9b6p
title: BindingDB Entry 50034051: Discovery of 1-arylcarbonyl-6,7-dimethoxyisoquinoline derivatives as glutamine fructose-6-phosphate amidotransferase (GFAT) inhibitors.

description: Small molecule binding data for protein Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1, Uniprot Q06210
DOI: 10.7270/q22n52k4
title: BindingDB Entry 50033187: Discovery of indole alkaloids with cannabinoid CB1 receptor antagonistic activity.

description: Small molecule binding data for protein Cannabinoid receptor 1, Uniprot P21554
DOI: 10.7270/q23778zg
title: BindingDB Entry 50032366: Elucidation of the active conformation of the amino terminus of receptor-bound secretin using intramolecular disulfide bond constraints.

description: Small molecule binding data for protein Secretin receptor, Uniprot P47872
DOI: 10.7270/q23n23qh
title: BindingDB Entry 50033179: Imidazo[1,5-a]pyrazines: orally efficacious inhibitors of mTORC1 and mTORC2.

description: Small molecule binding data for protein 3-phosphoinositide dependent protein kinase-1, C-RAF, Dual specificity mitogen-activated protein kinase kinase 1, Epidermal growth factor receptor, Insulin receptor, Insulin-like growth factor I receptor, PI3-kinase subunit gamma, Tyrosine-protein kinase ABL1, VEGF-receptor 2 and tyrosine-protein kinase SRC, and Vascular endothelial growth factor receptor 2, Uniprot O15530, P00519, P00533, P04049, P06213, P08069, P12931, P35968, P48736, and Q02750
DOI: 10.7270/q25b02w3
title: BindingDB Entry 50034050: Indolin-2-one p38a inhibitors III: bioisosteric amide replacement.

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 1B, C-RAF, Cytochrome P450 1A, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), Cytochrome P450 3A, Mitogen-activated protein kinase 14, and Neurotrophic tyrosine kinase receptor, Uniprot P04049, P04629, P05177, P08684, P10635, P11712, P28222, P33261, and Q16539
DOI: 10.7270/q26973z1
title: BindingDB Entry 50034042: Synthesis and Toll-like receptor 4 (TLR4) activity of phosphatidylinositol dimannoside analogues.

description: Small molecule binding data for protein Toll-like receptor 4/MD-2/CD14, Uniprot Q9QUK6
DOI: 10.7270/q26d5t9g
title: BindingDB Entry 50033186: Hybrid compounds as new Bcr/Abl inhibitors.

description: Small molecule binding data for protein Breakpoint cluster region protein /Tyrosine-protein kinase ABL, Uniprot P00519 and P11274
DOI: 10.7270/q27081nr
title: BindingDB Entry 50032365: Identification of selective norbornane-type aspartate analogue inhibitors of the glutamate transporter 1 (GLT-1) from the chemical universe generated database (GDB).

description: Small molecule binding data for protein Excitatory Amino Acid EAAT2 and Excitatory amino acid transporter 3, Uniprot P43004 and P43005
DOI: 10.7270/q28s4q1p
title: BindingDB Entry 50031406: Novel tetrahydrochinoline derived CETP inhibitors.

description: Small molecule binding data for protein Cholesteryl ester transfer protein, Uniprot P11597
DOI: 10.7270/q28w3dc3
title: BindingDB Entry 50030426: Potential antioxidants and tyrosinase inhibitors from synthetic polyphenolic deoxybenzoins.

description: Small molecule binding data for protein Tyrosinase, Uniprot O42713
DOI: 10.7270/q2930tjj
title: BindingDB Entry 50034049: Discovery of novel 3,5-disubstituted indole derivatives as potent inhibitors of Pim-1, Pim-2, and Pim-3 protein kinases.

description: Small molecule binding data for protein Serine/threonine-protein kinase PIM, Tyrosine-protein kinase Kit (Kit), Tyrosine-protein kinase receptor FLT3, and Vascular endothelial growth factor receptor 2, Uniprot P10721, P11309, P35968, P36888, Q86V86, and Q9P1W9
DOI: 10.7270/q29z95b1
title: BindingDB Entry 50034041: Synthesis, pharmacophore modeling and in vitro activity of 10,11-dihydrodibenzo[b,f]oxepine-4-carboxamide derivatives as novel and potent antagonists of the prostaglandin EP4 receptor.

description: Small molecule binding data for protein Prostaglandin E2 receptor EP2 subtype (EP2) and Prostaglandin E2 receptor EP4 subtype (EP4), Uniprot P35408 and P43116
DOI: 10.7270/q2b56k16
title: BindingDB Entry 50033185: Discovery of 3-aryl-5-acylpiperazinyl-pyrazoles as antagonists to the NK3 receptor.

description: Small molecule binding data for protein Cytochrome P450 1A, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), Cytochrome P450 3A, Neurokinin 1 receptor, Neurokinin 2 receptor, and Neurokinin 3 receptor, Uniprot P05177, P08684, P10635, P11712, P16177, P21452, P25103, P29371, and P33261
DOI: 10.7270/q2dj5fr0
title: BindingDB Entry 50031405: SAR and optimization of thiazole analogs as potent stearoyl-CoA desaturase inhibitors.

description: Small molecule binding data for protein Fatty acid desaturase 1, Fatty acid desaturase 2, Stearoyl-CoA desaturase 1, and Stearoyl-CoA desaturase 1 (SCD1), Uniprot O00767, O60427, O95864, and P07308
DOI: 10.7270/q2dn453t
title: BindingDB Entry 50030425: Synthesis and biological evaluation of novel carbon-11 labeled pyridyl ethers: candidate ligands for in vivo imaging of alpha4beta2 nicotinic acetylcholine receptors (alpha4beta2-nAChRs) in the brain with positron emission tomography.

description: Small molecule binding data for protein Neuronal acetylcholine receptor, Neuronal acetylcholine receptor subunit alpha-2, and Neuronal acetylcholine receptor subunit alpha-3, Uniprot P04757, P09483, and P12389
DOI: 10.7270/q2dr2vx4
title: BindingDB Entry 50034048: Identification of novel plasmin inhibitors possessing nitrile moiety as warhead.

description: Small molecule binding data for protein Plasma kallikrein (KLKB1) and Plasminogen, Uniprot P00747 and P03952
DOI: 10.7270/q2ft8mbw
title: BindingDB Entry 50033184: Discovery of triazine-benzimidazoles as selective inhibitors of mTOR.

description: Small molecule binding data for protein C-RAF, Casein kinase I isoform delta, PI3-kinase subunit alpha, PI3-kinase subunit beta, PI3-kinase subunit delta, PI3-kinase subunit gamma, Serine/threonine-protein kinase mTOR, TGF-beta receptor type II, and Vascular endothelial growth factor receptor 2, Uniprot O00329, P04049, P35968, P37173, P42336, P42338, P42345, P48730, and P48736
DOI: 10.7270/q2j966h5
title: BindingDB Entry 50031404: Podophyllotoxin analogues active versus Trypanosoma brucei.

description: Small molecule binding data for protein Cyclooxygenase-2 (COX-2) and Prostaglandin G/H synthase (cyclooxygenase), Uniprot P05979 and Q05769
DOI: 10.7270/q2jd4wv6
title: BindingDB Entry 50030424: Synthesis of hybrid analogues of caffeine and eudistomin D and its affinity for adenosine receptors.

description: Small molecule binding data for protein Adenosine receptor A1, Adenosine receptor A2a, and Adenosine receptor A3, Uniprot P0DMS8, P29274, and P30542
DOI: 10.7270/q2jh3mkz
title: BindingDB Entry 50034047: Tetrahydroquinolines as a novel series of nonsteroidal selective androgen receptor modulators: structural requirements for better physicochemical and biological properties.

description: Small molecule binding data for protein Androgen receptor, Estrogen receptor, Glucocorticoid, Progesterone receptor, and mineralocorticoid, Uniprot P06186, P06211, P06536, P15207, and P22199
DOI: 10.7270/q2k937rw
title: BindingDB Entry 50032371: Synthesis and in vitro evaluation of N-alkyl-7-methoxytacrine hydrochlorides as potential cholinesterase inhibitors in Alzheimer disease.

description: Small molecule binding data for protein Acetylcholinesterase and Cholinesterase, Uniprot P06276 and P22303
DOI: 10.7270/q2kk9c2m
title: BindingDB Entry 50033183: 1,4-Diazepane compounds as potent and selective CB2 agonists: optimization of metabolic stability.

description: Small molecule binding data for protein Cannabinoid receptor 1, Cannabinoid receptor 2, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), and Cytochrome P450 3A, Uniprot P08684, P10635, P11712, P21554, and P34972
DOI: 10.7270/q2p26z8z
title: BindingDB Entry 50031403: Structure of human G protein-coupled receptor kinase 2 in complex with the kinase inhibitor balanol.

description: Small molecule binding data for protein Beta-adrenergic receptor kinase 2, G protein-coupled receptor kinase 4, G protein-coupled receptor kinase 5, G protein-coupled receptor kinase 6, G protein-coupled receptor kinase 7, G-protein coupled receptor kinase 2, and Rhodopsin kinase, Uniprot P25098, P32298, P34947, P35626, P43250, Q15835, and Q8WTQ7
DOI: 10.7270/q2p55nkx
title: BindingDB Entry 50030423: Design, synthesis and dopamine D4 receptor binding activities of new N-heteroaromatic 5/6-ring Mannich bases.

description: Small molecule binding data for protein DRD1, Dopamine receptor, and Dopamine receptor D2L/neurotensin receptor NTS1, Uniprot P14416, P35462, and Q95136
DOI: 10.7270/q2p84c9p
title: BindingDB Entry 50034046: Design, synthesis, and structure-activity relationships of spirolactones bearing 2-ureidobenzothiophene as acetyl-CoA carboxylases inhibitors.

description: Small molecule binding data for protein Acetyl-CoA carboxylase 1 (ACC1) and Acetyl-CoA carboxylase 2 (ACC2), Uniprot O00763 and Q13085
DOI: 10.7270/q2q240gm
title: BindingDB Entry 50032370: Thieno[3,2-c]pyrazoles: a novel class of Aurora inhibitors with favorable antitumor activity.

description: Small molecule binding data for protein AKT/p21CIP1, Aurora kinase B/Inner centromere protein, CDC7/DBF4 (Cell division cycle 7-related protein kinase/Activator of S phase kinase), CDK2/Cyclin A/Cyclin A1, Epidermal growth factor receptor, Fibroblast growth factor receptor 1, Focal adhesion kinase 1/vascular endothelial growth factor receptor 3, Glycogen synthase kinase-3, Hepatocyte growth factor receptor, High affinity immunoglobulin gamma Fc receptor I, IKK epsilon/TBK1, Inhibitor of NF-kappa-B kinase (IKK), Insulin receptor, JAK3/JAK1, Kinesin-1 heavy chain/ Tyrosine-protein kinase receptor RET, MAP kinase ERK2, MAP kinase-activated protein kinase 2, Mitogen-activated protein kinase 14, Neurotrophic tyrosine kinase receptor, PKC alpha and beta-2, Pyruvate dehydrogenase kinase isoenzyme 1 (PDK1), SRC, Serine/threonine-protein kinase Aurora, Serine/threonine-protein kinase Aurora-C, Serine/threonine-protein kinase Chk1, Serine/threonine-protein kinase MST4, Serine/threonine-protein kinase NIM1, Serine/threonine-protein kinase PAK 4, Serine/threonine-protein kinase PLK1, Tyrosine-protein kinase ABL1, Tyrosine-protein kinase BRK, Tyrosine-protein kinase JAK2, Tyrosine-protein kinase Kit (Kit), Tyrosine-protein kinase ZAP-70, Vascular endothelial growth factor receptor 2, and cAMP-dependent protein kinase (PKA), Uniprot O00311, O14757, O14920, O14965, O60674, O96013, P00519, P00533, P04629, P05771, P06213, P06239, P07948, P07949, P08581, P10721, P11362, P12314, P17612, P20248, P24941, P28482, P31749, P35916, P35968, P43403, P49137, P49841, P52333, P53350, P78396, Q13882, Q14164, Q15118, Q16539, Q8IY84, Q96GD4, Q9P289, and Q9UQB9
DOI: 10.7270/q2qc03sg
title: BindingDB Entry 50033182: Pyridinesulfonylureas and pyridinesulfonamides as selective bombesin receptor subtype-3 (BRS-3) agonists.

description: Small molecule binding data for protein BRS3 and Bombesin receptor subtype-3, Uniprot O54798 and P32247
DOI: 10.7270/q2st7pzh
title: BindingDB Entry 50031402: Insight into binding of phosphodiesterase-9A selective inhibitors by crystal structures and mutagenesis.

description: Small molecule binding data for protein Phosphodiesterase 9A, Uniprot O76083
DOI: 10.7270/q2sx6d9b
title: BindingDB Entry 50030422: Design and synthesis of ten biphenyl-neolignan derivatives and their in vitro inhibitory potency against cyclooxygenase-1/2 activity and 5-lipoxygenase-mediated LTB4-formation.

description: Small molecule binding data for protein 5-lipoxygenase/FLAP, Prostaglandin G/H synthase (Cyclooxygenase-2), and Prostaglandin G/H synthase (cyclooxygenase), Uniprot P05979, P09917, and P79208
DOI: 10.7270/q2t1542v
title: BindingDB Entry 50034045: Synthesis and biological evaluation of new 3-(6-hydroxyindol-2-yl)-5-(Phenyl) pyridine or pyrazine V-Shaped molecules as kinase inhibitors and cytotoxic agents.

description: Small molecule binding data for protein Cyclin-Dependent Kinase 5 (CDK5), Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A, and Glycogen synthase kinase-3, Uniprot Q00535, Q15078, and Q63470
DOI: 10.7270/q2v40vht
title: BindingDB Entry 50033181: Structure-based virtual screening approach to the discovery of phosphoinositide 3-kinase alpha inhibitors.

description: Small molecule binding data for protein PI3-kinase subunit alpha, Uniprot P42336
DOI: 10.7270/q2xg9r8x
title: BindingDB Entry 50031401: Synthesis and preclinical evaluations of 2-(2-fluorophenyl)-6,7-methylenedioxyquinolin-4-one monosodium phosphate (CHM-1-P-Na) as a potent antitumor agent.

description: Small molecule binding data for protein Cathepsin D, Cathepsin E, Cathepsin S, Cytochrome P450 2D6 (2D6), Protein tyrosine phosphatase type IVA 1, Protein tyrosine phosphatase type IVA 2, and Protein-tyrosine phosphatase 4A3, Uniprot O75365, P07339, P10635, P14091, P25774, Q12974, and Q93096
DOI: 10.7270/q2xp750m
title: BindingDB Entry 50030421: Synthesis and biological evaluation of novel 4-azaindolyl-indolyl-maleimides as glycogen synthase kinase-3beta (GSK-3beta) inhibitors.

description: Small molecule binding data for protein Dual specificity mitogen-activated protein kinase kinase 1, Glycogen synthase kinase-3, Inhibitor of NF-kappa-B kinase (IKK), Mitogen-activated protein kinase 3, Protein kinase C, epsilon, and Serine/threonine-protein kinase Aurora, Uniprot O14920, O14965, P27361, P49841, Q02156, and Q02750
DOI: 10.7270/q2xs5vtx
title: BindingDB Entry 50034044: Design and synthesis of a library of chemokine antagonists.

description: Small molecule binding data for protein C-C chemokine receptor type 1, C-C chemokine receptor type 2, C-C chemokine receptor type 3, and C-C chemokine receptor type 5, Uniprot O95950, P32246, P41597, P51677, and P51681
DOI: 10.7270/q2zk5gwh
title: BindingDB Entry 50032368: 4-methylpteridinones as orally active and selective PI3K/mTOR dual inhibitors.

description: Small molecule binding data for protein AKT/p21CIP1 and Serine/threonine-protein kinase mTOR, Uniprot P31749 and P42345
DOI: 10.7270/q2zw1m77
title: BindingDB Entry 50033180: 8-Hydroxynaphthalene-1,4-dione derivative as novel compound for glioma treatment.

description: Small molecule binding data for protein Dual-specificity tyrosine-phosphorylation regulated kinase 1A and Serine/threonine-protein kinase Aurora, Uniprot O14965 and Q13627
DOI: 10.7270/q20c4vwx
title: BindingDB Entry 50031418: Azole-based inhibitors of AKT/PKB for the treatment of cancer.

description: Small molecule binding data for protein AKT/p21CIP1, Cyclin-dependent kinase 1, Cyclin-dependent kinase 2, Tyrosine-protein kinase Kit (Kit), and Vascular endothelial growth factor receptor 2, Uniprot P06493, P10721, P24941, P31749, and P35968
DOI: 10.7270/q20g3k69
title: BindingDB Entry 50030438: Synthesis, structure-activity relationships, and biological profiles of a dihydrobenzoxathiin class of histamine H(3) receptor inverse agonists.

description: Small molecule binding data for protein Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), Cytochrome P450 3A, Histamine H1 receptor, Histamine H2 Receptor, Histamine H3 receptor, Histamine receptor (H3), Histamine receptor (H4), and Voltage-gated potassium channel, Uniprot P08684, P10635, P11712, P25021, P35367, P58406, Q12809, Q9H3N8, Q9QYN8, and Q9Y5N1
DOI: 10.7270/q20k290z
title: BindingDB Entry 50034059: AHL-dependent quorum sensing inhibition: synthesis and biological evaluation ofa-(N-alkyl-carboxamide)-¿-butyrolactones anda-(N-alkyl-sulfonamide)-¿-butyrolactones.

description: Small molecule binding data for protein Transcriptional activator protein luxR, Uniprot P12746
DOI: 10.7270/q21n81fr
title: BindingDB Entry 50033195: Inhibitors of the oncogenic transcription factor AP-1 from Podocarpus latifolius.

description: Small molecule binding data for protein Transcription factor AP-1, Uniprot P05412
DOI: 10.7270/q22b8z7f
title: BindingDB Entry 50032376: Structural basis for binding of cyclic 2-oxoglutarate analogues to factor-inhibiting hypoxia-inducible factor.

description: Small molecule binding data for protein Hypoxia-inducible factor prolyl hydroxylase 1, Uniprot Q96KS0
DOI: 10.7270/q2416x6b
title: BindingDB Entry 50031417: Exploration of SAR features by modifications of thiazoleacetic acids as CRTH2 antagonists.

description: Small molecule binding data for protein Chemoattractant receptor-homologous molecule expressed on Th2 cells, G protein-coupled receptor 44, Prostanoid DP receptor, and Prostanoid TP receptor, Uniprot P21731, P70263, Q13258, Q6XKD3, Q9Y5Y4, and Q9Z2J6
DOI: 10.7270/q24749xm
title: BindingDB Entry 50030436: Discovery of beta-homophenylalanine based pyrrolidin-2-ylmethyl amides and sulfonamides as highly potent and selective inhibitors of dipeptidyl peptidase IV.

description: Small molecule binding data for protein Dipeptidyl peptidase 2 (DPP II), Dipeptidyl peptidase 4 (DPP4), Dipeptidyl peptidase IX, and Dipeptidyl peptidase VIII, Uniprot P27487, Q6V1X1, Q86TI2, and Q9UHL4
DOI: 10.7270/q24b31rq
title: BindingDB Entry 50034058: A fluorescent probe for GM1 gangliosidosis relatedß-galactosidase: N-(dansylamino)hexylaminocarbonylpentyl-1,5-dideoxy-1,5-imino-D-galactitol.

description: Small molecule binding data for protein α-galactosidase, Beta-galactosidase, and beta-Galactosidase (β-gal), Uniprot P00722, P16278, and Q42656
DOI: 10.7270/q2513z98
title: BindingDB Entry 50031407: Structure-based drug design enables conversion of a DFG-in binding CSF-1R kinase inhibitor to a DFG-out binding mode.

description: Small molecule binding data for protein Macrophage colony stimulating factor receptor, Uniprot P07333
DOI: 10.7270/q2571c1z
title: BindingDB Entry 50030427: Bicyclic cyanothiazolidines as novel dipeptidyl peptidase 4 inhibitors.

description: Small molecule binding data for protein Dipeptidyl peptidase 4 (DPP4) and Fibroblast activation protein alpha, Uniprot P27487 and Q12884
DOI: 10.7270/q25d8s53
title: BindingDB Entry 50033194: (Z)-3-butylidenephthalide from Ligusticum porteri , ana-glucosidase inhibitor.

description: Small molecule binding data for protein Alpha-glucosidase MAL62, Uniprot P07265
DOI: 10.7270/q26110jc
title: BindingDB Entry 50032374: Structure-based design and synthesis of potent, ethylenediamine-based, mammalian farnesyltransferase inhibitors as anticancer agents.

description: Small molecule binding data for protein Geranylgeranyl transferase type 1, Geranylgeranyl transferase type I beta subunit/Protein Farnesyltransferase (PFT), Protein Farnesyltransferase (PFT), and Protein farnesyltransferase beta/geranylgeranyltransferase type I alpha subunit, Uniprot P49354, P49356, P53609, Q61239, Q8BUY9, and Q8K2I1
DOI: 10.7270/q27s7nww
title: BindingDB Entry 50031416: Design, synthesis and evaluation of carbamate-modified (-)-N(1)-phenethylnorphysostigmine derivatives as selective butyrylcholinesterase inhibitors.

description: Small molecule binding data for protein Acetylcholinesterase and Butyrylcholinesterase, Uniprot P21836 and Q03311
DOI: 10.7270/q28052nb
title: BindingDB Entry 50030435: Structure-activity relationships of memoquin: Influence of the chain chirality in the multi-target mechanism of action.

description: Small molecule binding data for protein Acetylcholinesterase and Cholinesterase, Uniprot P06276 and P22303
DOI: 10.7270/q2833sg2
title: BindingDB Entry 50034057: Discovery of a new class of glucosylceramide synthase inhibitors.

description: Small molecule binding data for protein Ceramide glucosyltransferase and Cytochrome P450 3A, Uniprot P08684 and Q16739
DOI: 10.7270/q2959hwd
title: BindingDB Entry 50033193: Discovery of benzothiazole-based adenosine A2B receptor antagonists with improved A2A selectivity.

description: Small molecule binding data for protein Adenosine receptor A1, Adenosine receptor A2a, Adenosine receptor A2b, Adenosine receptor A3, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), Cytochrome P450 3A, and Voltage-gated potassium channel, Uniprot P08684, P0DMS8, P10635, P11712, P29274, P29275, P30542, P33261, and Q12809
DOI: 10.7270/q29s1r7z
title: BindingDB Entry 50032373: Substituted 4-amino-1H-pyrazolo[3,4-d]pyrimidines as multi-targeted inhibitors of insulin-like growth factor-1 receptor (IGF1R) and members of ErbB-family receptor kinases.

description: Small molecule binding data for protein Epidermal growth factor receptor, Epidermal growth factor receptor and ErbB2 (HER1 and HER2), and Insulin-like growth factor I receptor, Uniprot P00533, P04626, and P08069
DOI: 10.7270/q2cj8dmm
title: BindingDB Entry 50031415: 2-Anilino-4-aryl-1,3-thiazole inhibitors of valosin-containing protein (VCP or p97).

description: Small molecule binding data for protein Valosin containing protein, p97 subunit, Uniprot P55072
DOI: 10.7270/q2cn73z1
title: BindingDB Entry 50030434: Synthesis and structure-activity relationships of gamma-carboline derivatives as potent and selective cysLT(1) antagonists.

description: Small molecule binding data for protein Cysteinyl leukotriene receptor 1, Uniprot Q2NNR5