cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.14285702
title: Effect of replacing fish meal by full fat soybean meal on growth performance, feed utilization and gastrointestinal enzymes in diets for African catfish Clarias gariepinus

description: Abstract Study aimed to evaluate the effect of replacing fish meal with different levels of full fat soybean meal (FFSBM) on growth and digestive enzyme activities in the stomach, Liver and intestine for Clarias gariepinus. Four diets (D1, D2, D3 and D4) were formulated with 0, 15, 20 and 20 g 100-1 protein + DL-methionine by alternating FFSBM with fish meal. The growth of C. gariepinus was found to be significantly decreased when FFSBM replacement increased. Final body weight was 89.69, 79.70, 70.82 and 68.29 g for fish fed on D1, D2, D3 and D4, respectively, with significant differences between treatments. Specific growth rate (SGR) ranged between 3.11 to 2.78%. Proteolytic activity was higher only with alkaline pHs, whereas only very low activity was shown with acidic. Results of liver showed approximately similar results at acid and alkaline. In contrast, higher proteolytic activity in the stomach was observed at acid pHs 3.0 and 4.0 μg tyrosine-1 minute-1 mg-1 protein) whereas lower values were observed at neutral pH 7.0 g tyrosine-1 minute-1 mg-1 protein for catfish fed on the experimental diets. Moreover, trypsin activity was higher for the stomach, followed by the intestine and liver. However, higher amount of amylase observed in the liver than intestine and stomach.
DOI: 10.6084/m9.figshare.14285700
title: Wildlife rehabilitation: A case study of the neo-tropical, opossum Didelphis marsupialis insularis, Allen 1902.

description: Abstract Wildlife rehabilitation facilities in the Caribbean region are limited, yet they can provide relevant information on wild populations. Didelphis marsupialis insularis is a popularly hunted, under-studied, neo-tropical marsupial species that is increasingly being admitted for rehabilitation. The aim of this study was 1. To record the experiences of rehabilitating D. marsupialis insularis in the neo-tropical island of Trinidad and Tobago and 2. To extract and highlight information on the biology of this opossum sub-species. Using admission records, obtained over a roughly four year period, two breeding periods (February to March and August to October) were illustrated. Litter sizes averaged five individuals, with a range of 1 to 8 young. This species was found to be common in urban areas of the country, with dog attacks reported as the major cause for admission. Thus the information recorded by this wildlife rehabilitation facility has provided great insight on the sparsely studied opossum, D. marsupialis insularis.
DOI: 10.6084/m9.figshare.14285697
title: Apparent nutrient digestibility of carbohydrate (corn) in Cirrhinus mrigala under the influence of chromium chloride hexahydrate

description: Abstract A feeding trial was carried out to assess the effect of dietary chromium supplementation on apparent nutrient digestibility coefficient (%) of gelatinized and non-gelatinized corn in Cirrhinus mrigala fingerlings for 90 days. Using various levels of chromium chloride hexahydrate six test diets designated as T1 (G/0.0 Cr2Cl3.6H2O mg Kg-1), T2 (NG/0.0 Cr2Cl3.6H2O mg Kg-1), T3 (G/0.2 Cr2Cl3.6H2O mg Kg-1), T4 (NG/0.2 Cr2Cl3.6H2O mg Kg-1), T5 (G/0.4 Cr2Cl3.6H2O mg Kg-1) and T6 (NG/0.4 Cr2Cl3.6H2O mg Kg-1) were prepared. Results showed highest apparent digestibility coefficient (ADC) of nutrients dry matter, crude lipid and gross energy in test diet T5 that was gelatinized and supplemented with chromium 0.4 mg/Kg while, for crude protein higher value of nutrient digestibility was recorded in T3 test diet (G/0.2 Cr2Cl3.6H2O mg/Kg). It was concluded that chromium supplementation with gelatinized corn in fish (Cirrhinus mrigala) diet can improve the nutrients digestibility more efficiently.
DOI: 10.6084/m9.figshare.14285695
title: Gastrointestinal helminths in dog feces surrounding suburban areas of Lower Dir district, Pakistan: A public health threat

description: Abstract Data on environmental contamination of the parasites of zoonotic importance is scarce in Pakistan. Soil contamination with feces of dogs hide infective stages of the parasite represents a health-risk to humans. This study was aimed to assess the eggs of gastrointestinal parasites of stray dogs and household dogs in lower Dir district, Pakistan with special consideration to those that can be spread to humans. One hundred and fifty two stool specimens from (stray dogs=90 and household dogs=62) were collected. The helminth eggs were processed by direct smear method and centrifugation techniques and identified by microscopic examination. Of the total examined dogs 26.8% (n=41 /152) were found to be infected with one or more intestinal parasites. The intestinal helminths detected were Dipylidium caninum (n =18, 11.8%), followed by Toxocara canis (n =16, 10.5%), Taenia spp., (n=10, 6.57%) Ancylostoma caninum (n=6, 3.94), Toxascaris spp., Capillaria spp., and Trichuris vulpis (n=2, 1.31% each) in order of their prevalence. Pattern of infection revealed that 27 (65.8%) dogs have single, 13(31.7%) double and 1(2.43%) triple infection. The stray dogs were highly infected 34.4% (n=31) than house hold dogs 16.1% (n=10). The prevalence of infection with intestinal parasites was significantly different among these two groups (p = 0.0097). This study highlight a severe environmental contamination by frequent parasitic stages infectious to humans. There is a higher risk of zoonotic transmission from dogs which indicate an immediate need for the controlling of these parasites and educating the public to take wise action relating to the parasites and pets.
DOI: 10.6084/m9.figshare.14285693
title: Evaluation of cell damage and modulation of cytokines TNF-α, IL-6 and IL-10 in macrophages exposed to PpIX-mediated photodynamic therapy

description: Abstract Little is known regarding whether photodynamic therapy (PDT)-induced cell death can substantially compromise macrophages (MΦ), which are important cells in PDT-induced immune responses. Here, parameters of PDT-mediated MΦ cytotoxicity and cytokine production in response to protoporphyrin IX (PpIX) were evaluated. Peritoneal MΦ from BALB/c mice were stimulated in vitro with PDT, light, PpIX, or lipopolysaccharide (LPS). After that, cell viability, lipid peroxidation, Nitric Oxide (NO), DNA damage, TNF-α, IL-6 and IL-10 were evaluated. Short PDT exposure reduced cell viability by 10–30%. There was a two-fold increase in NO and DNA degradation, despite the non-increase in lipoperoxidation. PDT increased TNF-α and IL-10, particularly in the presence of LPS, and decreased the production of IL-6 to 10-fold. PDT causes cellular stress, induces NO radicals and leads to DNA degradation, generating a cytotoxic microenvironment. Furthermore, PDT modulates pro- and anti-inflammatory cytokines in MΦ.
DOI: 10.6084/m9.figshare.14285691
title: Stock assessment of the peacock bass Cichla temensis (Humboldt, 1821), an important fishing resource from the middle Negro river, Amazonas, Brazil

description: Abstract Peacock bass Cichla temensis is an important species at the Amazon basin, since commercial, subsistence and recreational fisheries simultaneously exploit it. Cichla temensis is the preferred species by recreational fishers and it has been strongly exploited, mainly at the Negro river, the second largest tributary of the Amazon River. It was used data from experimental fisheries, collected at the middle stretch of Negro river, which were coupled with previously published data on its population dynamics, to run a yield per recruit model and build scenarios of sustainable fisheries. The results showed that the age of the first catch is a key variable to successful management of the peacock bass stocks at this region.
DOI: 10.7270/q2gb26n5
title: BindingDB Entry 50002168: Regioselectivity of thiouracil alkylation: Application to optimization of Darapladib synthesis.

description: Small molecule binding data for protein LDL-associated phospholipase A2, Uniprot Q13093
DOI: 10.7270/q2319zg5
title: BindingDB Entry 50002171: Design, synthesis and biological evaluation of new carbazole derivatives as anti-cancer and anti-migratory agents.

description: Small molecule binding data for protein Ras-related C3 botulinum toxin substrate 1/T-lymphoma invasion and metastasis-inducing protein 1, Uniprot A4D2P1 and P63000
DOI: 10.7270/q26t0q81
title: BindingDB Entry 50002170: Synthesis of deuterium-labelled analogues of NLRP3 inflammasome inhibitor MCC950.

description: Small molecule binding data for protein NLRP3 protein, Uniprot Q96P20
DOI: 10.7270/q2z89g08
title: BindingDB Entry 50002172: Binding-Site Compatible Fragment Growing Applied to the Design of β

description: Small molecule binding data for protein Adrenergic receptor, Uniprot P07550 and X5DQM5
DOI: 10.7270/q2th8q90
title: BindingDB Entry 50002174: Identification of novel plasminogen activator inhibitor-1 inhibitors with improved oral bioavailability: Structure optimization of N-acylanthranilic acid derivatives.

description: Small molecule binding data for protein Plasminogen activator inhibitor-1, Uniprot A0A024QYT5 and P05121
DOI: 10.7270/q2pv6nz4
title: BindingDB Entry 50002175: Identification and optimization of soluble epoxide hydrolase inhibitors with dual potency towards fatty acid amide hydrolase.

description: Small molecule binding data for protein Acyl coenzyme A:cholesterol acyltransferase, Anandamide amidohydrolase, Arylacetamide deacetylase, Carboxylesterase 2, EBifunctional epoxide hydrolase 2, Epoxide hydratase, Epoxide hydrolase 1, Epoxide hydrolase 2, Fatty-acid amide hydrolase 1, Serum paraoxonase/arylesterase 1, Serum paraoxonase/arylesterase 2, and Serum paraoxonase/lactonase 3, Uniprot O00519, O00748, O08914, P07099, P22760, P23141, P27169, P34913, P34914, P80299, P97612, Q15165, Q15166, and R4SBI6
DOI: 10.7270/q2k35x8k
title: BindingDB Entry 50002176: Discovery of selective 2,4-diaminoquinazoline toll-like receptor 7 (TLR 7) agonists.

description: Small molecule binding data for protein Cytochrome P450 1A, Cytochrome P450 2C19, Cytochrome P450 2C8, Cytochrome P450 2C9, Cytochrome P450 2D6, and Cytochrome P450 3A, Uniprot C1ID52, P05177, P08684, P10632, P10635, P11712, P33261, Q6GRK0, and S5RV20
DOI: 10.7270/q29k4dth
title: BindingDB Entry 50002178: Synthesis, biological evaluation and docking study of a new series of di-substituted benzoxazole derivatives as selective COX-2 inhibitors and anti-inflammatory agents.

description: Small molecule binding data for protein Prostaglandin E synthase/G/H synthase 2 and Prostaglandin G/H synthase (cyclooxygenase), Uniprot P05979 and P35354
DOI: 10.7270/q2fb55j7
title: BindingDB Entry 50002177: Surrogating and redirection of pyrazolo[1,5-a]pyrimidin-7(4H)-one core, a novel class of potent and selective DPP-4 inhibitors.

description: Small molecule binding data for protein Dipeptidyl peptidase 4, Dipeptidyl peptidase 8/9, and Dipeptidyl peptidase 9, Uniprot A0A024R5Z6, P27487, Q6V1X1, and Q86TI2
DOI: 10.7270/q25t3p2r
title: BindingDB Entry 50002179: Selective inhibition of monoamine oxidase A by hispidol.

description: Small molecule binding data for protein Amine oxidase (flavin-containing) A and Amine oxidase [flavin-containing] B, Uniprot P21397, P27338, and Q53YE7
DOI: 10.7270/q2222xbb
title: BindingDB Entry 50002180: Design and synthesis of novel dasatinib derivatives as inhibitors of leukemia stem cells.

description: Small molecule binding data for protein Bcr-Abl, Uniprot A0A024R8E2, P00519, and P11274
DOI: 10.7270/q2x92dwg
title: BindingDB Entry 50002181: Synthesis and biological evaluation of a series of novel pyridinecarboxamides as potential multi-receptor antipsychotic drugs.

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 1A, 5-hydroxytryptamine receptor 2A, 5-hydroxytryptamine receptor 2C, Alpha-1A adrenergic receptor, D(2) dopamine receptor, and Histamine H1 receptor, Uniprot A0A024R3C5, P08908, P14416, P28223, P28335, P35348, P35367, and Q5ZGX3
DOI: 10.7270/q2nv9mwn
title: BindingDB Entry 50002184: 2-Formyl-komarovicine promotes adiponectin production in human mesenchymal stem cells through PPARγ partial agonism.

description: Small molecule binding data for protein Peroxisome proliferator-activated receptor, Uniprot P37231
DOI: 10.7270/q2sn0ckg
title: BindingDB Entry 50002182: Potent human glutaminyl cyclase inhibitors as potential anti-Alzheimer's agents: Structure-activity relationship study of Arg-mimetic region.

description: Small molecule binding data for protein Glutaminyl-peptide cyclotransferase, Uniprot Q16769
DOI: 10.7270/q2j38w63
title: BindingDB Entry 50002186: Synthesis, kinetics and inhibition of Escherichia coli Heptosyltransferase I by monosaccharide analogues of Lipid A.

description: Small molecule binding data for protein Lipopolysaccharide heptosyltransferase 1, Uniprot P24173
DOI: 10.7270/q2db84gr
title: BindingDB Entry 50002187: Semisynthesis and biological evaluation of a cotylenin A mimic derived from fusicoccin A.

description: Small molecule binding data for protein 14-3-3 protein zeta/delta, Uniprot D0PNI1 and P63104
DOI: 10.7270/q24t6mzd
title: BindingDB Entry 50002189: A multicomponent approach in the discovery of indoleamine 2,3-dioxygenase 1 inhibitors: Synthesis, biological investigation and docking studies.

description: Small molecule binding data for protein Indoleamine 2,3-dioxygenase, Uniprot A0A348GSI3 and P14902
DOI: 10.7270/q28k7cp4
title: BindingDB Entry 50002188: Development of a series of novel o-phenylenediamine-based indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors.

description: Small molecule binding data for protein Indoleamine 2,3-dioxygenase, Uniprot A0A348GSI3 and P14902
DOI: 10.7270/q2125w8v
title: BindingDB Entry 50002191: Structural development of tetrachlorophthalimides as liver X receptor β (LXRβ)-selective agonists with improved aqueous solubility.

description: Small molecule binding data for protein Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta, Uniprot F1D8N1, P55055, Q13133, and Q60644
DOI: 10.7270/q2wd435t
title: BindingDB Entry 50002192: Structure-activity studies of a macrocyclic peptide inhibitor of histone lysine demethylase 4A.

description: Small molecule binding data for protein Lysine-specific demethylase 4A and Lysine-specific demethylase 4C, Uniprot O75164 and Q9H3R0
DOI: 10.7270/q2rn3bgj
title: BindingDB Entry 50002193: Synthesis of novel multivalent fluorescent inhibitors with high affinity to prostate cancer and their biological evaluation.

description: Small molecule binding data for protein Glutamate carboxypeptidase II, Uniprot Q04609
DOI: 10.7270/q2h41v1t
title: BindingDB Entry 50002195: Fluorous-tag assisted synthesis of a glycosaminoglycan mimetic tetrasaccharide as a high-affinity FGF-2 and midkine ligand.

description: Small molecule binding data for protein Fibroblast growth factor 2 and Midkine, Uniprot P09038 and P21741
DOI: 10.7270/q2mw2krt
title: BindingDB Entry 50002194: Design, synthesis and evaluation of 4'-OH-flurbiprofen-chalcone hybrids as potential multifunctional agents for Alzheimer's disease treatment.

description: Small molecule binding data for protein Amine oxidase (flavin-containing) A and Amine oxidase [flavin-containing] B, Uniprot P21397, P27338, and Q53YE7
DOI: 10.7270/q2cc1381
title: BindingDB Entry 50002198: Activation loop targeting strategy for design of receptor-interacting protein kinase 2 (RIPK2) inhibitors.

description: Small molecule binding data for protein Serine/threonine-protein kinase RIPK2, Uniprot A0A0S2Z4Z8 and O43353
DOI: 10.7270/q23t9kt1
title: BindingDB Entry 50002200: Discovery of novel potent HCV NS5B polymerase non-nucleoside inhibitors bearing a fused benzofuran scaffold.

description: Small molecule binding data for protein Hepatitis C virus NS5B RNA-dependent RNA polymerase and Nonstructural protein 5A, Uniprot Q5L478 and Q8JXU8
DOI: 10.7270/q27m0bhv
title: BindingDB Entry 50002199: Heterobicyclic inhibitors of transforming growth factor beta receptor I (TGFβRI).

description: Small molecule binding data for protein TGF-beta receptor type II and TGF-beta receptor type-1, Uniprot A3QNQ0, P36897, P37173, and Q5T7S2
DOI: 10.7270/q2057jhb
title: BindingDB Entry 50002201: Novel naftopidil derivatives containing methyl phenylacetate and their blocking effects on α

description: Small molecule binding data for protein Adrenergic receptor alpha, Alpha adrenergic receptor (1a and 1d), and Alpha-1A adrenergic receptor, Uniprot B0ZBE0, P25100, P35348, and P35368
DOI: 10.7270/q2vd722w
title: BindingDB Entry 50002202: Design, synthesis, and biological evaluation of inhibitors of the NADPH oxidase, Nox4.

description: Small molecule binding data for protein NADPH oxidase 4, Uniprot Q9NPH5
DOI: 10.7270/q2kw5jmf
title: BindingDB Entry 50002205: Design, synthesis, anti-inflammatory activity and molecular docking of potential novel antipyrine and pyrazolone analogs as cyclooxygenase enzyme (COX) inhibitors.

description: Small molecule binding data for protein Prostaglandin G/H synthase (cyclooxygenase), Uniprot P05979
DOI: 10.7270/q2qn69cm
title: BindingDB Entry 50002203: Diastereoselective synthesis of fused cyclopropyl-3-amino-2,4-oxazine β-amyloid cleaving enzyme (BACE) inhibitors and their biological evaluation.

description: Small molecule binding data for protein Beta-secretase (BACE), Uniprot A0A024R3D7 and P56817
DOI: 10.7270/q2bc4236
title: BindingDB Entry 50002207: Design and synthesis of 4-(2,3-dihydro-1H-benzo[d]pyrrolo[1,2-a]imidazol-7-yl)-N-(5-(piperazin-1-ylmethyl)pyridine-2-yl)pyrimidin-2-amine as a highly potent and selective cyclin-dependent kinases 4 and 6 inhibitors and the discovery of structure-activity relationships.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2, Cyclin-dependent kinase 1/ G1/S-specific cyclin-D3, Cyclin-dependent kinase 4, and Cyclin-dependent kinase 6/G1/S-specific cyclin D1, Uniprot A0A024RBB6, P06493, P11802, P24385, P30281, P40989, Q00534, and Q6FI00
DOI: 10.7270/q2g44svk
title: BindingDB Entry 50002206: Discovery of chromenes as inhibitors of macrophage migration inhibitory factor.

description: Small molecule binding data for protein Macrophage migration inhibitory factor (MIF), Uniprot I4AY87 and P14174
DOI: 10.7270/q26m39dx
title: BindingDB Entry 50002209: Synthesis of polyozellin, a prolyl oligopeptidase inhibitor, and its structural revision.

description: Small molecule binding data for protein Prolyl endopeptidase and Prolyl oligopeptidase family protein, Uniprot A6H249 and P48147
DOI: 10.7270/q22z184c
title: BindingDB Entry 50002210: Novel nicotinamide analog as inhibitor of nicotinamide N-methyltransferase.

description: Small molecule binding data for protein Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A, Nicotinamide N-methyltransferase, and Nicotinamide N-methyltransferase (NNMT), Uniprot C1ID52, O55239, P08684, P10635, P11712, P33261, P40261, Q6FH49, Q6GRK0, and S5RV20
DOI: 10.7270/q2z60rpf
title: BindingDB Entry 50002211: Pharmacology and in vivo efficacy of pyridine-pyrimidine amides that inhibit microtubule polymerization.

description: Small molecule binding data for protein Cytochrome P450 1A, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6, and Cytochrome P450 3A, Uniprot C1ID52, P05177, P08684, P10635, P11712, P33261, Q6GRK0, and S5RV20
DOI: 10.7270/q2tf00z3
title: BindingDB Entry 50002212: Structure-based design and synthesis of macrocyclic human rhinovirus 3C protease inhibitors.

description: Small molecule binding data for protein Genome polyprotein, Uniprot P03303
DOI: 10.7270/q2jw8hg2
title: BindingDB Entry 50002214: Discovery of morpholine-based aryl sulfonamides as Na

description: Small molecule binding data for protein Sodium channel protein type 2 alpha subunit, Sodium channel protein type 5 subunit alpha, Sodium channel protein type 8 subunit alpha, and Sodium channel protein type 9 subunit alpha, Uniprot Q14524, Q15858, Q99250, and Q9UQD0
DOI: 10.7270/q2pn9877
title: BindingDB Entry 50002213: MF-8, a novel promising arylpiperazine-hydantoin based 5-HT

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 7, Uniprot P34969
DOI: 10.7270/q2f47rq6
title: BindingDB Entry 50002215: Investigating PKA-RII specificity using analogs of the PKA:AKAP peptide inhibitor STAD-2.

description: Small molecule binding data for protein cAMP-dependent protein kinase type II-alpha regulatory subunit and cAMP-dependent protein kinase type II-beta regulatory subunit, Uniprot A0A024R2W3, A0A024R712, P13861, and P31323
DOI: 10.7270/q25q4zpg
title: BindingDB Entry 50002217: Design, synthesis, and discovery of 5-((1,3-diphenyl-1H-pyrazol-4-yl)methylene)pyrimidine-2,4,6(1H,3H,5H)-triones and related derivatives as novel inhibitors of mPGES-1.

description: Small molecule binding data for protein Prostaglandin E synthase, Uniprot O14684
DOI: 10.7270/q29c711q
title: BindingDB Entry 50002216: Design, synthesis and anticancer activities evaluation of novel 5H-dibenzo[b,e]azepine-6,11-dione derivatives containing 1,3,4-oxadiazole units.

description: Small molecule binding data for protein Poly [ADP-ribose] polymerase 1, Uniprot A0A024R3T8 and P09874
DOI: 10.7270/q21z471f
title: BindingDB Entry 50002218: Discovery of N-arylpyrroles as agonists of GPR120 for the treatment of type II diabetes.

description: Small molecule binding data for protein Free fatty acid receptor 1, Free fatty acid receptor 4, G-protein coupled receptor 120, and Omega-3 fatty acid receptor 1, Uniprot O14842, Q2AC31, Q3V2S5, Q5NUL3, Q76JU9, and Q7TMA4
DOI: 10.7270/q2sf2zrf
title: BindingDB Entry 50002220: A small group of sulfated benzofurans induces steady-state submaximal inhibition of thrombin.

description: Small molecule binding data for protein Thrombin and coagulation factor X, Uniprot P00734
DOI: 10.7270/q2np2702
title: BindingDB Entry 50002221: Novel inhibitors of Staphylococcus aureus RnpA that synergize with mupirocin.

description: Small molecule binding data for protein Ribonuclease P protein component, Uniprot A0A0T7MWK2 and P0A0H5
DOI: 10.7270/q2x63qj2
title: BindingDB Entry 50002219: Structure-based design and biological evaluation of inhibitors of the pseudomonas aeruginosa heme oxygenase (pa-HemO).

description: Small molecule binding data for protein Heme oxygenase, Uniprot O69002
DOI: 10.7270/q2d50qkc
title: BindingDB Entry 50002223: Development of Potent Inhibitors of Receptor Tyrosine Kinases by Ligand-Based Drug Design and Target-Biased Phenotypic Screening.

description: Small molecule binding data for protein ALK tyrosine kinase receptor, Aurora kinase A/Targeting protein for Xklp2, Aurora kinase B, Epidermal growth factor receptor, Epithelial discoidin domain-containing receptor 1, Hepatocyte growth factor receptor, Mast/stem cell growth factor receptor Kit, Platelet-derived growth factor receptor, Proto-oncogene tyrosine-protein kinase Src, Proto-oncogene tyrosine-protein kinase receptor Ret, RAC-alpha serine/threonine-protein kinase AKT1, Tyrosine-protein kinase Mer, Tyrosine-protein kinase receptor FLT3, Tyrosine-protein kinase receptor TYRO3, Tyrosine-protein kinase receptor UFO, Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2), and mTOR/FKBP12A/FKBP12B, Uniprot A0A024R759, A0A024R7T2, A0A024RCL1, B0LPE5, O14965, P00533, P07949, P08581, P10721, P12931, P16234, P30530, P31749, P35968, P36888, P42345, Q06418, Q08345, Q12866, Q96GD4, and Q9UM73
DOI: 10.7270/q2hx1g8b
title: BindingDB Entry 50002222: Discovery and validation of 2-styryl substituted benzoxazin-4-ones as a novel scaffold for rhomboid protease inhibitors.

description: Small molecule binding data for protein Alpha-chymotrypsin, Uniprot P00766