cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7511066
title: Evaluation of the dentin changes in teeth subjected to endodontic treatment and photodynamic therapy

description: Abstract Introduction Antimicrobial photodynamic therapy (PDT) is an efficient adjuvant technique to promote disinfection of the root canal system. Therefore, it is important to investigate changes to dentin morphology and permeability induced by the use of diode laser on the root dentin. Objective The purpose of this study was to investigate morphological changes and the percentage of apical leakage after the use of laser. Material and method Forty single-rooted teeth were instrumented using rotary system and irrigated. Teeth were randomly divided in two groups: G1 - not exposed to PDT (control), and G2 - pretreated with toluidine blue photosensitizer and irradiated with AsGaAl laser diode. Ten teeth in each group were evaluated by SEM for morphological changes. The other ten teeth were filled and stained with Rhodamine B to evaluate the apical leakage. Result The results showed significant difference between G1 and G2 (p &lt;0.001 - chi-square), with greater presence of debris in G1 and higher incidence of open dentinal tubules in G2. Erosions and cracks were observed in both groups, with no statistically significant difference (p&gt; 0.001). The apical leakage was significantly higher in G2 than in G1 (p &lt;0.001 - Student's t-test). Conclusion It was concluded that the use of low-level laser reduced the smear layer and opened the dentinal tubules. Use of laser increased the permeability of the apical dentin.
DOI: 10.6084/m9.figshare.7513055
title: Cytotoxicity and genotoxicity in water of the Subaé River (Humildes, Bahia, Brazil) using Allium cepa L. as a bioindicator

description: Over the years, the Subaé River in Bahia has been polluted by the discharge of toxic industrial waste into its waters. This study used the Allium cepa test to investigate the cytotoxic and genotoxic effects caused by the river water that that runs through the city of Humildes-BA. Water samples were collected in three points (PI, PII and PIII) for physical and chemical analysis. Onions bulbs were immersed in triplicate water samples for 72 h to induce germination. The root tips were kept at 4 °C for 12-h, then fixed in Carnoy for 12-h and stained using the Feulgen technique. We analyzed 6500 cells of each treatment. Cytotoxicity was assessed by the mitotic index (MI) and genotoxicity by chromosomal abnormalities (CA). The tests revealed that PI and PIII had DO values, BOD5 and COD changed. The toxicity test indicated that root growth was inhibited by the water drawn from PI (10.3%) and PII (10.6%) compared to the negative control (11.9%). CAs were found in 6.2% of the cells relating to PI, 6.0% relating to PII, and 5.4% relating to PIII, respectively. These values were higher than those found in the positive control (3%), indicating a genotoxic effect at the points studied. From the results, it can be inferred that the waters of the Rio Subaé may contain substances that are probably affecting the cell cycle of A. cepa. It is important that other analyses be conducted in different seasons, in order to better monitor local environmental conditions.
DOI: 10.6084/m9.figshare.7676666.v1
title: Impact of Periodontal Disease on Late Morbimortality (10 Years) of Pacientes with Acute Coronary Syndrome

description: Abstract Background: It is known that predisposing factors for periodontal disease (PD) and cardiovascular diseases are similar, just as dissemination of oral flora pathogens can induce the development of cardiovascular diseases, which play a direct role on the morbimortality of patients. Objective: To assess the impact of periodontal disease in the presence of acute coronary syndrome on late morbimortality after long-term follow-up of patients (10 years). Methods: The historical prospective study of continuous assessment was based on the evaluation of 345 medical records of patients hospitalized for acute coronary syndrome, divided into 3 groups: edentulous, with periodontal disease and without periodontal disease. The patients studied were in the ICU, in 2006, with a clinical picture of acute coronary syndrome submitted to invasive stratification with coronary angiography on the basis of clinical indication and were reassessed over the next 10 years. The qualitative variables were compared using the Chi-square test. Long-term mortality was assessed using the Kaplan-Meier curves, quantified with the hazard ratio (HR) and a confidence interval of 95% and compared through Cox regression. P values of less than or equal to 0.05 were regarded as statistically significant. Results: Of the 345 patients, 233 had at least one coronary obstruction greater than or equal to 50%, being the main group for comparison according to the different status of periodontal disease (without periodontal disease, with periodontal disease and edentulous). In this cardiovascular condition, we found a difference in mortality among edentulous patients compared to those free of periodontal disease, with a p = 0.004 and a hazard ratio of 10.496 (95% CI: 4.988-22.089). A significant difference was also noted between edentulous patients and patients with periodontal disease, with a p = 0.0017 and a hazard ratio of 2.512 (95% CI: 1.491-4.234). Conclusion: A significant increase in mortality was found according with the progression of periodontal disease, which justifies its classification as an important risk factor for the development of cardiovascular diseases, as well as the need for prevention and treatment of oral diseases.
DOI: 10.6084/m9.figshare.7513055.v1
title: Cytotoxicity and genotoxicity in water of the Subaé River (Humildes, Bahia, Brazil) using Allium cepa L. as a bioindicator

description: Over the years, the Subaé River in Bahia has been polluted by the discharge of toxic industrial waste into its waters. This study used the Allium cepa test to investigate the cytotoxic and genotoxic effects caused by the river water that that runs through the city of Humildes-BA. Water samples were collected in three points (PI, PII and PIII) for physical and chemical analysis. Onions bulbs were immersed in triplicate water samples for 72 h to induce germination. The root tips were kept at 4 °C for 12-h, then fixed in Carnoy for 12-h and stained using the Feulgen technique. We analyzed 6500 cells of each treatment. Cytotoxicity was assessed by the mitotic index (MI) and genotoxicity by chromosomal abnormalities (CA). The tests revealed that PI and PIII had DO values, BOD5 and COD changed. The toxicity test indicated that root growth was inhibited by the water drawn from PI (10.3%) and PII (10.6%) compared to the negative control (11.9%). CAs were found in 6.2% of the cells relating to PI, 6.0% relating to PII, and 5.4% relating to PIII, respectively. These values were higher than those found in the positive control (3%), indicating a genotoxic effect at the points studied. From the results, it can be inferred that the waters of the Rio Subaé may contain substances that are probably affecting the cell cycle of A. cepa. It is important that other analyses be conducted in different seasons, in order to better monitor local environmental conditions.
DOI: 10.6084/m9.figshare.7514453
title: Imaging Alzheimer's disease pathophysiology with PET

description: ABSTRACT Alzheimer's disease (AD) has been reconceptualised as a dynamic pathophysiological process characterized by preclinical, mild cognitive impairment (MCI), and dementia stages. Positron emission tomography (PET) associated with various molecular imaging agents reveals numerous aspects of dementia pathophysiology, such as brain amyloidosis, tau accumulation, neuroreceptor changes, metabolism abnormalities and neuroinflammation in dementia patients. In the context of a growing shift toward presymptomatic early diagnosis and disease-modifying interventions, PET molecular imaging agents provide an unprecedented means of quantifying the AD pathophysiological process, monitoring disease progression, ascertaining whether therapies engage their respective brain molecular targets, as well as quantifying pharmacological responses. In the present study, we highlight the most important contributions of PET in describing brain molecular abnormalities in AD.
DOI: 10.6084/m9.figshare.7514453.v1
title: Imaging Alzheimer's disease pathophysiology with PET

description: ABSTRACT Alzheimer's disease (AD) has been reconceptualised as a dynamic pathophysiological process characterized by preclinical, mild cognitive impairment (MCI), and dementia stages. Positron emission tomography (PET) associated with various molecular imaging agents reveals numerous aspects of dementia pathophysiology, such as brain amyloidosis, tau accumulation, neuroreceptor changes, metabolism abnormalities and neuroinflammation in dementia patients. In the context of a growing shift toward presymptomatic early diagnosis and disease-modifying interventions, PET molecular imaging agents provide an unprecedented means of quantifying the AD pathophysiological process, monitoring disease progression, ascertaining whether therapies engage their respective brain molecular targets, as well as quantifying pharmacological responses. In the present study, we highlight the most important contributions of PET in describing brain molecular abnormalities in AD.
DOI: 10.6084/m9.figshare.7676666
title: Impact of Periodontal Disease on Late Morbimortality (10 Years) of Pacientes with Acute Coronary Syndrome

description: Abstract Background: It is known that predisposing factors for periodontal disease (PD) and cardiovascular diseases are similar, just as dissemination of oral flora pathogens can induce the development of cardiovascular diseases, which play a direct role on the morbimortality of patients. Objective: To assess the impact of periodontal disease in the presence of acute coronary syndrome on late morbimortality after long-term follow-up of patients (10 years). Methods: The historical prospective study of continuous assessment was based on the evaluation of 345 medical records of patients hospitalized for acute coronary syndrome, divided into 3 groups: edentulous, with periodontal disease and without periodontal disease. The patients studied were in the ICU, in 2006, with a clinical picture of acute coronary syndrome submitted to invasive stratification with coronary angiography on the basis of clinical indication and were reassessed over the next 10 years. The qualitative variables were compared using the Chi-square test. Long-term mortality was assessed using the Kaplan-Meier curves, quantified with the hazard ratio (HR) and a confidence interval of 95% and compared through Cox regression. P values of less than or equal to 0.05 were regarded as statistically significant. Results: Of the 345 patients, 233 had at least one coronary obstruction greater than or equal to 50%, being the main group for comparison according to the different status of periodontal disease (without periodontal disease, with periodontal disease and edentulous). In this cardiovascular condition, we found a difference in mortality among edentulous patients compared to those free of periodontal disease, with a p = 0.004 and a hazard ratio of 10.496 (95% CI: 4.988-22.089). A significant difference was also noted between edentulous patients and patients with periodontal disease, with a p = 0.0017 and a hazard ratio of 2.512 (95% CI: 1.491-4.234). Conclusion: A significant increase in mortality was found according with the progression of periodontal disease, which justifies its classification as an important risk factor for the development of cardiovascular diseases, as well as the need for prevention and treatment of oral diseases.
DOI: 10.6084/m9.figshare.7451798.v1
title: Structural and Floristic Variations in an Atlantic Subtropical Rainforest in Southern Brazil

description: ABSTRACT The Atlantic Subtropical Rainforest covers a huge area of Santa Catarina state, starting on the coast and going through the Serra Geral. Along its distribution, the vegetation changes according to altitude, geomorphology, and soil. In the attempt to evaluate vegetation variations related to different soil types in an Atlantic Forest remnant, 43 plots of 200 m2 were sampled. All the individuals with DBH ≥ 5.0 cm were measured. We have found consistent floristic and structural variations, which separated sample plots with Litholic Neosol and Rogosol situated in slopes from those with Yellow-Red Ultisol and Haplic Cambisol, as well as plots with Fluvic Neosol from Haplic Gleisol in plateaus. Species richness increased according to water availability and soil depth, with the plateaus’ soils being the richest. Each area was characterized by a range of indicator species and the results indicated that soil attributes are important drivers of vegetation variation.
DOI: 10.6084/m9.figshare.7508399
title: Self-esteem and dental caries in adolescents: a cross sectional study

description: Abstract Introduction Dental caries in adolescents remains an important public health problem, but its relationship with psychological factors are poorly studied. Objective To study the possible association between aspects of self-esteem and dental caries in adolescents. Material and method A cross-sectional study involving a sample of 409 adolescents from 13 Southern Brazilian municipalities was carried out. Dental caries status was assessed through the World Health Organization criteria. For questions related to self-esteem the Rosenberg Self-Esteem Scale was used. The outcomes were each question of the scale. The chi-square test was used to determine statistical significance of associations. To adjust for confounding variables, the Poisson loglinear with robust estimator was used. Result Positive associations were observed for the presence of decayed teeth and “At times, I think I am no good at all” (p&lt;0.001), “I wish I could have more respect for myself” (p= 0.016), “I certainly feel useless at times” (p= 0.022) and negative association with “On the whole, I am satisfied with myself” (p= 0.022). In the adjusted analysis, adolescents with decayed teeth had a higher prevalence of positive responses to “At times, I think I am no good at all” [(PR= 1.23 (CI 95% 1.05; 1.44)], and negative responses for “On the whole, I am satisfied with myself” [(PR= 1.12 (CI 95% 1.02; 1.24)]. Conclusion Aspects of self-esteem were significantly and independently associated with the presence of decayed teeth.
DOI: 10.6084/m9.figshare.7508399.v1
title: Self-esteem and dental caries in adolescents: a cross sectional study

description: Abstract Introduction Dental caries in adolescents remains an important public health problem, but its relationship with psychological factors are poorly studied. Objective To study the possible association between aspects of self-esteem and dental caries in adolescents. Material and method A cross-sectional study involving a sample of 409 adolescents from 13 Southern Brazilian municipalities was carried out. Dental caries status was assessed through the World Health Organization criteria. For questions related to self-esteem the Rosenberg Self-Esteem Scale was used. The outcomes were each question of the scale. The chi-square test was used to determine statistical significance of associations. To adjust for confounding variables, the Poisson loglinear with robust estimator was used. Result Positive associations were observed for the presence of decayed teeth and “At times, I think I am no good at all” (p&lt;0.001), “I wish I could have more respect for myself” (p= 0.016), “I certainly feel useless at times” (p= 0.022) and negative association with “On the whole, I am satisfied with myself” (p= 0.022). In the adjusted analysis, adolescents with decayed teeth had a higher prevalence of positive responses to “At times, I think I am no good at all” [(PR= 1.23 (CI 95% 1.05; 1.44)], and negative responses for “On the whole, I am satisfied with myself” [(PR= 1.12 (CI 95% 1.02; 1.24)]. Conclusion Aspects of self-esteem were significantly and independently associated with the presence of decayed teeth.
DOI: 10.6084/m9.figshare.7514585
title: Effect of three months of periodized hydrogymnastics exercise program on urinary concentration of deoxypyridinoline in older women

description: ABSTRACT Objective To determine the effect of three months of periodized hydrogymnastics exercise program on urinary concentration of deoxypyridinoline in older women. Subjects and methods Twenty-six subjects were randomly assigned in two, intervention group (n = 16) and control group (n = 10). The intervention group followed 12-week of periodized hydrogymnastics training program five times a week, 50 minutes of water exercise with work heart rate reserve of 40-50% (1-6thweek) increasing the load to 50-60% (7-12th week); the control group was not involved in exercise and remained sedentary. The urinary concentration of deoxypyridinoline was evaluated by high resolution liquid chromatography using the reactive immulite pyrilinks-D siemens medical solutions, pretest at the baseline and at the end post-test of the 12-week of water-exercise. As statistical analyses mixed 2 x 2 ANOVA was used, also percentage changes (Δ %) was calculated. Results The results did not show significant improvement (p &lt; 0.05) comparing the interaction intergroup and the measurements of urinary concentration of deoxypyridinoline (p = 0.504), percentage change (Δ %) showed positive improvements in the experimental group of -13.7 (nM/mMcreatine) in comparison with -7.1 (nM/mMcreatine) from the control group. Conclusion The present study involves periodization increasing the load heart rate reserve of hydrogymnastics exercise in order to produce grater adaptations, but the results showed than is not possible to infer that hydrogymnastics is effective in increase urinary concentration of deoxypyridinoline in older women, will be appropriated in the future more studies to better clarify the possibilities of improvements between hydrogymnastics and urinary concentration of deoxypyridinoline. Arch Endocrinol Metab. 2015;59(6):523-7
DOI: 10.6084/m9.figshare.7452377
title: GENESIS AND CHARACTERISTICS OF SOILS OF THE SANTANAMOUNTAIN RANGE IN THE SERIDÓ REGION, RIO GRANDE DO NORTE, BRAZIL

description: ABSTRACT Rio Grande do Norte has mountain formations with edaphoclimatic conditions different from those predominating in the state, presenting deeper,acid soils, and milder climate. Among these formations, is the Santana mountain range, which is part of the Serra do Martins Formation. The objective of this work was to interpret the pedogenesis of the representative soils of the Santana mountain range through morphological, physical, and chemical characterizations of soil profiles and evaluate the effect of these attributes on the distribution of pedological forms along the landscape using multivariate analysis. Morphological, physical, and chemical analyses of seven soil profiles of the Santana mountain range were performed. The soils were classified according to the Brazilian Soil Classification System and the data subjected to multivariate analysis. The representative soil classes found were: LATOSSOLO AMARELO Distrófico argissólico; LATOSSOLO AMARELO Eutrófico argissólico; NEOSSOLO QUARTZARÊNICO Órtico típico; NEOSSOLO LITÓLICO Eutrófico fragmentário; NEOSSOLO REGOLÍTICO Eutrófico típico and CAMBISSOLO HÁPLICO Tb Eutrófico léptico. According to the analysis of the morphological attributes, the parent material had great influence on the formation of the different soil classes found in the Santana mountain range. The soil textural classes varied from sand to sandy clay loam. According to the analysis of the chemical attributes, the soil profiles presented acid reaction, great variation of base saturation, and low electrical conductivity. The multivariate analysis established groups of representative soil profiles of the Santana mountain range through the distinction of their physical and chemical attributes, mainly of subsurface diagnostic horizons.
DOI: 10.6084/m9.figshare.7514585.v1
title: Effect of three months of periodized hydrogymnastics exercise program on urinary concentration of deoxypyridinoline in older women

description: ABSTRACT Objective To determine the effect of three months of periodized hydrogymnastics exercise program on urinary concentration of deoxypyridinoline in older women. Subjects and methods Twenty-six subjects were randomly assigned in two, intervention group (n = 16) and control group (n = 10). The intervention group followed 12-week of periodized hydrogymnastics training program five times a week, 50 minutes of water exercise with work heart rate reserve of 40-50% (1-6thweek) increasing the load to 50-60% (7-12th week); the control group was not involved in exercise and remained sedentary. The urinary concentration of deoxypyridinoline was evaluated by high resolution liquid chromatography using the reactive immulite pyrilinks-D siemens medical solutions, pretest at the baseline and at the end post-test of the 12-week of water-exercise. As statistical analyses mixed 2 x 2 ANOVA was used, also percentage changes (Δ %) was calculated. Results The results did not show significant improvement (p &lt; 0.05) comparing the interaction intergroup and the measurements of urinary concentration of deoxypyridinoline (p = 0.504), percentage change (Δ %) showed positive improvements in the experimental group of -13.7 (nM/mMcreatine) in comparison with -7.1 (nM/mMcreatine) from the control group. Conclusion The present study involves periodization increasing the load heart rate reserve of hydrogymnastics exercise in order to produce grater adaptations, but the results showed than is not possible to infer that hydrogymnastics is effective in increase urinary concentration of deoxypyridinoline in older women, will be appropriated in the future more studies to better clarify the possibilities of improvements between hydrogymnastics and urinary concentration of deoxypyridinoline. Arch Endocrinol Metab. 2015;59(6):523-7
DOI: 10.6084/m9.figshare.7452377.v1
title: GENESIS AND CHARACTERISTICS OF SOILS OF THE SANTANAMOUNTAIN RANGE IN THE SERIDÓ REGION, RIO GRANDE DO NORTE, BRAZIL

description: ABSTRACT Rio Grande do Norte has mountain formations with edaphoclimatic conditions different from those predominating in the state, presenting deeper,acid soils, and milder climate. Among these formations, is the Santana mountain range, which is part of the Serra do Martins Formation. The objective of this work was to interpret the pedogenesis of the representative soils of the Santana mountain range through morphological, physical, and chemical characterizations of soil profiles and evaluate the effect of these attributes on the distribution of pedological forms along the landscape using multivariate analysis. Morphological, physical, and chemical analyses of seven soil profiles of the Santana mountain range were performed. The soils were classified according to the Brazilian Soil Classification System and the data subjected to multivariate analysis. The representative soil classes found were: LATOSSOLO AMARELO Distrófico argissólico; LATOSSOLO AMARELO Eutrófico argissólico; NEOSSOLO QUARTZARÊNICO Órtico típico; NEOSSOLO LITÓLICO Eutrófico fragmentário; NEOSSOLO REGOLÍTICO Eutrófico típico and CAMBISSOLO HÁPLICO Tb Eutrófico léptico. According to the analysis of the morphological attributes, the parent material had great influence on the formation of the different soil classes found in the Santana mountain range. The soil textural classes varied from sand to sandy clay loam. According to the analysis of the chemical attributes, the soil profiles presented acid reaction, great variation of base saturation, and low electrical conductivity. The multivariate analysis established groups of representative soil profiles of the Santana mountain range through the distinction of their physical and chemical attributes, mainly of subsurface diagnostic horizons.