cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.7030786
title: Nesting Tasks Dataset for 2D-Nesting Efficiency Estimation

description: Nesting efficiency dataset This is the raw dataset associated with the paper “Graph Neural Networks Comparison for 2D-Nesting Efficiency Estimation”, by C.Lallier, L. Vézard, B. Pinaud and G. Blin, 2022. Consisting of 100,000 nesting tasks. <strong>Usage:</strong> The files are: <em>tasks.gz, parts.gz, constraints.gz, </em>and<em> shapes.gz</em>. They are in PICKLE file format version 5 with a gzip compression. Example to load a file : <pre><code class="language-python">import pandas as pd tasks = pd.read_pickle('tasks.gz')</code></pre> <strong>Description:</strong> <em>Tasks.gz</em> file contains nestings high-level descriptors. It is composed of the following columns: Column Type Description efficiency float The variable to predict (label). Given in % duration integer input data. The nesting algorithm convergence time. Given in s. sheet_width integer input data. The width of the nesting area. Given in m<sup>-4</sup> sheet_length integer input data. Facultative. The height of the nesting area. Given in m<sup>-4</sup> sheet_type integer input data. Kind of the nesting. tasks_index integer Generated data. Join key between tables. is_train, is_val, is_test boolean Generated data. Can be used as mask for the train, val and test subsets. <em>Parts.gz</em> contains description of the parts to be nested : Column Type Description <strong>tasks_index</strong> integer Reference to the join key from the <em>Task</em> table. <strong>parts_id</strong> integer Generated part id. <strong>shape_hash</strong> integer Reference to the hash of the part's shape, join key from the <em>Shape </em>table. <em>Shapes.gz</em> is the description of the shapes of the parts to be nested : Column Type Description <strong>shape_hash</strong> integer Generated data. Join key between tables. <strong>raw</strong> list of integers List of x, y tuples for each point. Unit is m<sup>-4</sup> <strong>sizes</strong> list of integers List of sub-shapes sizes. <em>Constraints.gz</em> describes constraints and their parameters: Column Type Description <strong>type</strong> string Generated constraint type. <strong>tasks_index</strong> integer Reference to the join key from the <em>Task</em> table. <strong>parts_1, parts_2</strong> list of integers References to the <em>parts_id</em> from the <em>Parts</em> table. <strong>p1_x, p1_y and p2_x, p2_y</strong> list of floats Input data. Origin position (x, y) of the constraint on parts. For each part of the constraint. <strong>r1_start, r1_end, r1_flip_x</strong> list of floats Input data. Rotation (start, end, and flip_x) parameters of the constraint. Multiple ranges accepted. <strong>y_min, y_max</strong> list of floats Input data. Range from (y_min, y_max). Multiple ranges accepted. <strong>x_offset, y_offset, motif_order, x_alignment_type, y_alignment_type, proximity_type, max_distance, groups_relative_orientation, is_frozen</strong> float Input data. Other constraint parameters.
description: Fix an error in 'constraints.gz', swap 'c8' and 'g4' values in column 'type'
DOI: 10.6084/m9.figshare.20709604
title: Datasets. Determinants of PU

description: The dataset for a scale development study. The scale evaluation process was detailed.
DOI: 10.15468/dl.3xwsyd
title: Occurrence Download

description: A dataset containing 371 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Populus talassica Kom."
 ]
}

 The dataset includes 371 records from 16 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0021186-250402121839773/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.21856314.v1
title: Numerical and theoretical investigation of bolted sleeve connections with rectangular hollow sections

description: Abstract This article presents a theoretical and numerical study of bolted sleeve connections with rectangular hollow sections (RHS) under axial tension and compression. The geometric form of a hollow section provides resistance for high axial loads, torsion and combines effects, spreading its utilization in truss systems. In this context, the sleeve connections proposed explore these characteristics of RHS and offer an attractive aesthetic appearance for the continuity of elements. The bolted sleeve connection with RHS is formed by two outer tubes connected by an inner tube and staggered bolts. Herein, a parametric study was developed for identification of the failure modes in the connection. Finite element models with different geometric parameters and number of bolts were created in commercial software. The width, depth and thickness of RHS tubes and diameter of bolts were variated. In the theoretical/numerical/parametric results, the yielding gross section failure, the fracture through the effective net area failure and the bearing failure were observed. These failure modes occurred in both outer and inner tubes. The load results were compared to determine the resistance capacity of sleeve connections. The theoretical formulations were evaluated for representation of the ultimate load of the failure modes.
DOI: 10.6084/m9.figshare.21907560
title: Trends in Brazilian Research in Ergology

description: Abstract This article aims to analyze trends in research on Ergology in Brazil published from 1997 to 2019, considering the nature of the publication and the potential impact of the databases in which they are published. Studies related to occupational health indicate the growing influence of Ergology in the understanding of the world of work, a fact evidenced in previous bibliometric research, of lesser breadth and scope of the databases investigated, which is why we intend to cover gaps and broaden the analysis with more up-to-date data. Using descriptors peculiar to Ergology, surveys were conducted in the Web of Science, Scopus and SciELO databases, in journals not indexed to the databases cited, and in academic productions available in the Capes catalog. The projection of Brazil in studies on Ergology was revealed, with the Southeast being the region with the highest concentration of authors and volume of publications. However, the interrelationship between researchers tends to be limited to the institutions in which they work. There is a prevalence of theses and dissertations to the detriment of articles in productions related to Ergology. Publications point to interdisciplinarity - with a predominance of Occupational Health, Education, and Psychology - and tend to feature in vehicles of lesser scientific relevance.
DOI: 10.6084/m9.figshare.21907560.v1
title: Trends in Brazilian Research in Ergology

description: Abstract This article aims to analyze trends in research on Ergology in Brazil published from 1997 to 2019, considering the nature of the publication and the potential impact of the databases in which they are published. Studies related to occupational health indicate the growing influence of Ergology in the understanding of the world of work, a fact evidenced in previous bibliometric research, of lesser breadth and scope of the databases investigated, which is why we intend to cover gaps and broaden the analysis with more up-to-date data. Using descriptors peculiar to Ergology, surveys were conducted in the Web of Science, Scopus and SciELO databases, in journals not indexed to the databases cited, and in academic productions available in the Capes catalog. The projection of Brazil in studies on Ergology was revealed, with the Southeast being the region with the highest concentration of authors and volume of publications. However, the interrelationship between researchers tends to be limited to the institutions in which they work. There is a prevalence of theses and dissertations to the detriment of articles in productions related to Ergology. Publications point to interdisciplinarity - with a predominance of Occupational Health, Education, and Psychology - and tend to feature in vehicles of lesser scientific relevance.
DOI: 10.6084/m9.figshare.21907561
title: Metabolomic profiling and antidiabetic potential of Rumex vesicarius seed extract in high-fat diet and streptozotocin-induced diabeticrat

description: Abstract Rumex vesicarius hasbeen extensively used for the management of diabetes in the traditional system of medicine. The current study was designed to investigate antidiabetic and antihyperlipidemic effects of R.vesicarius and also to explore metabolomic profiling using UPLC-QTOF-MS. The effect of extracts was observed by checking the biochemical and histopathological parameters in diabetic rats. The results had shown a significant dose- dependent inhibition potential of aqueous extract of R. vesicarius seed against α-amylase and α-glucosidase along with significant inhibition in DPPH free-radical scavenging activity. Oral administration of R. vesicarius to diabetic rats significantly ( p&lt; 0.05) ameliorated blood glucose level. It also improved the function of the liver and kidney as well as ameliorated dyslipidemia in diabetic rats. Histopathological examination of the treatment groups reversed the damage of the pancreas, liver, and kidney tissues confirming the antidiabetic efficacy of R. vesicarius. UPLC- QTOF-MS analysis of the extract revealed a total of 42 bioactive compounds, which might contribute to the antidiabetic activity. Based on our findings, we can conclude that R. vesicarius might be a promising candidate for the management of diabetes.
DOI: 10.6084/m9.figshare.21907561.v1
title: Metabolomic profiling and antidiabetic potential of Rumex vesicarius seed extract in high-fat diet and streptozotocin-induced diabeticrat

description: Abstract Rumex vesicarius hasbeen extensively used for the management of diabetes in the traditional system of medicine. The current study was designed to investigate antidiabetic and antihyperlipidemic effects of R.vesicarius and also to explore metabolomic profiling using UPLC-QTOF-MS. The effect of extracts was observed by checking the biochemical and histopathological parameters in diabetic rats. The results had shown a significant dose- dependent inhibition potential of aqueous extract of R. vesicarius seed against α-amylase and α-glucosidase along with significant inhibition in DPPH free-radical scavenging activity. Oral administration of R. vesicarius to diabetic rats significantly ( p&lt; 0.05) ameliorated blood glucose level. It also improved the function of the liver and kidney as well as ameliorated dyslipidemia in diabetic rats. Histopathological examination of the treatment groups reversed the damage of the pancreas, liver, and kidney tissues confirming the antidiabetic efficacy of R. vesicarius. UPLC- QTOF-MS analysis of the extract revealed a total of 42 bioactive compounds, which might contribute to the antidiabetic activity. Based on our findings, we can conclude that R. vesicarius might be a promising candidate for the management of diabetes.
DOI: 10.6084/m9.figshare.21907563
title: The reliability and validity of decreased sound tolerance scale-screening

description: Abstract Objectives: Decreased Sound Tolerance (DST) is a negative reaction to a sound that does not cause any reaction in an individual with normal hearing. DST’s subclasses include hyperacusis, phonophobia, and misophonia, which are distinct and have therapy variations. There is no diagnostic method or scale that distinguishes them in the literature. This study’s purpose was to develop a screening scale that distinguishes these three DSTs. Methods: The study comprised 257 willing participants with normal hearing. Cronbach alpha coefficient, item-total correlation, and item differentiation of the Decreased Sound Tolerance Scale-Screening (DSTS-S) were evaluated. Structural validity of DSTS-S was performed by Varimax rotation with Kaiser normalization using Explanatory Factor Analysis (EFA), and Confirmatory Factor Analysis (CFA) was performed to assess its structural compatibility. The scale’s total scores from each section were compared using the Mann-Whitney U test in symptom (+) and symptom (–) participants. Results: The Cronbach alpha value for hyperacusis, phonophobia, and misophonia sections of DSTS-S was calculated as 0.881, 0.775, and 0.938, respectively. The difference between the independent samplet-test and the variables was statistically significant (p&lt;0.01). The Mann-Whitney U test showed a significant difference between the median values of the total groups ’scores with and without hyperacusis, phonophobia, and misophonia (HTS, PTS, and MTS, respectively) (p&lt;0.05). Evaluation by ROC analysis showed that hyperacusis was useful in predicting the presence of hyperacusis, phonophobia was useful in predicting the presence of phonophobia, and misophonia was useful in predicting the presence of misophonia (p&lt; 0.001). Hyperacusis and misophonia sections showed high reliability, and phonophobia section showed a moderately reliable level. The Kappa test showed that the compatibility between test–retest for the total scores was statistically significant (p &lt; 0.001). Conclusion: The study’s results indicated that DSTS-S is a valid and reliable scale for identifying subtypes/problems/classes of decreased sound tolerance.
DOI: 10.6084/m9.figshare.21907563.v1
title: The reliability and validity of decreased sound tolerance scale-screening

description: Abstract Objectives: Decreased Sound Tolerance (DST) is a negative reaction to a sound that does not cause any reaction in an individual with normal hearing. DST’s subclasses include hyperacusis, phonophobia, and misophonia, which are distinct and have therapy variations. There is no diagnostic method or scale that distinguishes them in the literature. This study’s purpose was to develop a screening scale that distinguishes these three DSTs. Methods: The study comprised 257 willing participants with normal hearing. Cronbach alpha coefficient, item-total correlation, and item differentiation of the Decreased Sound Tolerance Scale-Screening (DSTS-S) were evaluated. Structural validity of DSTS-S was performed by Varimax rotation with Kaiser normalization using Explanatory Factor Analysis (EFA), and Confirmatory Factor Analysis (CFA) was performed to assess its structural compatibility. The scale’s total scores from each section were compared using the Mann-Whitney U test in symptom (+) and symptom (–) participants. Results: The Cronbach alpha value for hyperacusis, phonophobia, and misophonia sections of DSTS-S was calculated as 0.881, 0.775, and 0.938, respectively. The difference between the independent samplet-test and the variables was statistically significant (p&lt;0.01). The Mann-Whitney U test showed a significant difference between the median values of the total groups ’scores with and without hyperacusis, phonophobia, and misophonia (HTS, PTS, and MTS, respectively) (p&lt;0.05). Evaluation by ROC analysis showed that hyperacusis was useful in predicting the presence of hyperacusis, phonophobia was useful in predicting the presence of phonophobia, and misophonia was useful in predicting the presence of misophonia (p&lt; 0.001). Hyperacusis and misophonia sections showed high reliability, and phonophobia section showed a moderately reliable level. The Kappa test showed that the compatibility between test–retest for the total scores was statistically significant (p &lt; 0.001). Conclusion: The study’s results indicated that DSTS-S is a valid and reliable scale for identifying subtypes/problems/classes of decreased sound tolerance.
DOI: 10.6084/m9.figshare.21907564
title: Piracetam-induced neuroprotection in lipopolysaccharides-challenged EOC-20 cells and mouse brain via attenuating oxidative stress

description: Abstract Therapeutically, piracetam has been used for decades as a cognitive enhancer for memory- related neuronal disorders. The present study aimed to investigate the neuroprotective potential of piracetam on lipopolysaccharides (LPS)-induced neuronal deficit using both in-vitro and in-vivo experimental models. For the in-vitro analysis, EOC-20 murine microglial cells were induced with a neuronal toxicity of 100 µg/ml of LPS, and the formation of intracellular reactive oxygen species (ROS) and nitric oxide (NO) productions were determined. For in-vivo neuroprotective analysis, groups of mice were treated orally with two doses of piracetam (200 and 400 mg/kg) for 30 days. Neuronal toxicity was induced by four intraperitoneal injections of LPS (250 µg/kg/day). The malondialdehyde (MDA) level was measured for oxidative stress, and catalase reduced glutathione (GSH), glutathione reductase (GRD), and superoxide dismutase (SOD) levels were determined as the antioxidant parameters. The result of the cell viability study was that pre-treatment with piracetam significantly protected the LPS-induced cell loss, and attenuated the ROS generation and NO production in LPS-induced EOC-20 cells. Moreover, the treatment of piracetam significantly reduced the MDA levels and improved catalase, GSH, GRD, and SOD activities in LPS-induced mice brains. The overall results from this study supported the neuroprotective effects of piracetam against LPS-induced neuronal toxicity.
DOI: 10.6084/m9.figshare.21907564.v1
title: Piracetam-induced neuroprotection in lipopolysaccharides-challenged EOC-20 cells and mouse brain via attenuating oxidative stress

description: Abstract Therapeutically, piracetam has been used for decades as a cognitive enhancer for memory- related neuronal disorders. The present study aimed to investigate the neuroprotective potential of piracetam on lipopolysaccharides (LPS)-induced neuronal deficit using both in-vitro and in-vivo experimental models. For the in-vitro analysis, EOC-20 murine microglial cells were induced with a neuronal toxicity of 100 µg/ml of LPS, and the formation of intracellular reactive oxygen species (ROS) and nitric oxide (NO) productions were determined. For in-vivo neuroprotective analysis, groups of mice were treated orally with two doses of piracetam (200 and 400 mg/kg) for 30 days. Neuronal toxicity was induced by four intraperitoneal injections of LPS (250 µg/kg/day). The malondialdehyde (MDA) level was measured for oxidative stress, and catalase reduced glutathione (GSH), glutathione reductase (GRD), and superoxide dismutase (SOD) levels were determined as the antioxidant parameters. The result of the cell viability study was that pre-treatment with piracetam significantly protected the LPS-induced cell loss, and attenuated the ROS generation and NO production in LPS-induced EOC-20 cells. Moreover, the treatment of piracetam significantly reduced the MDA levels and improved catalase, GSH, GRD, and SOD activities in LPS-induced mice brains. The overall results from this study supported the neuroprotective effects of piracetam against LPS-induced neuronal toxicity.
DOI: 10.6084/m9.figshare.21907566
title: Development and validation of a reversed-phase HPLC method for quantification of 1’-acetoxychavicol acetate content in a nanostructured lipid carrier formulation

description: Abstract 1’-acetoxychavicol acetate (ACA)-loaded nanostructured lipid carriers (NLCs) were formulated for prostate cancer therapy and to determine the optimal therapeutic dose, we developed a rapid, specific, and accurate reversed-phase high-performance liquid chromatography (RP-HPLC) method to quantify the ACA content in NLCs. The method was validated according to International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use (ICH) guidelines. Chromatographic separation of ACA from the lipid components was performed with an Agilent 1220 Infinity LC system and ultraviolet detector using an Agilent Poroshell C18 column (4.6 x 250.0 mm). The mobile phase consisted of acetonitrile and water (80:20 [v/v]) with a flow rate of 0.8 mL/min in isocratic mode. Linearity of the standard curve was assessed at an ACA concentration range of 5-200 µg/mL, and a 1/x weighted linear regression was adopted for the calibration curve. The calculated limits of detection and quantification were 0.59 µg/mL and 1.79 µg/mL, respectively. The mean percent recovery of ACA was 100.02% (relative SD, 2%), and the coefficients of variation for intraday and interday assays were within the values required by the ICH. We also demonstrated robustness of the method by altering the mobile phase ratio and flow rate. Furthermore, we proved specificity of the method for ACA by comparing chromatograms of the blank NLC and ACA-NLC. Hence, we effectively used this validated method to determine the drug-loading capacity and entrapment efficiency of the NLCs.
DOI: 10.6084/m9.figshare.21907566.v1
title: Development and validation of a reversed-phase HPLC method for quantification of 1’-acetoxychavicol acetate content in a nanostructured lipid carrier formulation

description: Abstract 1’-acetoxychavicol acetate (ACA)-loaded nanostructured lipid carriers (NLCs) were formulated for prostate cancer therapy and to determine the optimal therapeutic dose, we developed a rapid, specific, and accurate reversed-phase high-performance liquid chromatography (RP-HPLC) method to quantify the ACA content in NLCs. The method was validated according to International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use (ICH) guidelines. Chromatographic separation of ACA from the lipid components was performed with an Agilent 1220 Infinity LC system and ultraviolet detector using an Agilent Poroshell C18 column (4.6 x 250.0 mm). The mobile phase consisted of acetonitrile and water (80:20 [v/v]) with a flow rate of 0.8 mL/min in isocratic mode. Linearity of the standard curve was assessed at an ACA concentration range of 5-200 µg/mL, and a 1/x weighted linear regression was adopted for the calibration curve. The calculated limits of detection and quantification were 0.59 µg/mL and 1.79 µg/mL, respectively. The mean percent recovery of ACA was 100.02% (relative SD, 2%), and the coefficients of variation for intraday and interday assays were within the values required by the ICH. We also demonstrated robustness of the method by altering the mobile phase ratio and flow rate. Furthermore, we proved specificity of the method for ACA by comparing chromatograms of the blank NLC and ACA-NLC. Hence, we effectively used this validated method to determine the drug-loading capacity and entrapment efficiency of the NLCs.