cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.19904105.v1
title: Self-directed learning among primary health care doctors: an analysis in light of the theory of social representations

description: Abstract: Introduction: In a scenario of a great information availability, the production of scientific knowledge in medicine has been increasingly accelerated. The way the medical professional perceives and directs their acquisition of knowledge still lacks national studies, particularly in times of easily accessible internet. Objective: To analyze the social representations of physicians working in Primary Health Care (PHC) teams about self-directed learning. Method: This is a qualitative-quantitative study based on Moscovici’s Social Representations Theory, with a structural approach to Abric’s Central Core Theory, conducted in three municipalities of the state of Minas Gerais, Brazil. Semi-structured interviews were conducted on the subject, which were recorded and transcribed. The freely evoked words that emerged from the inducing term “medical self-learning” were analyzed with the aid of EVOC® software through the four-quadrant chart and CHIC® software analyzed the similarity. Content analysis was performed for the participants’ speeches. Results: Fifty interviews were carried out and the freely evoked words that possibly constitute the core of the representations were “knowledge”, “dedication”, “study”, “reading”, “need”, contrasting “research” and “book”. Conclusion: The results showed that the learners’ characteristics, practice as a learning locus as opposed to theory, associated with the time barrier, define the core content of the social representation of the participating physicians. In this assessed context, PHC reinforces its importance as a scenario for medical self-learning.
DOI: 10.6084/m9.figshare.19905434
title: Speech therapy, decision conflicts and dysphagic patients: an integrative review

description: Abstract Dysphagia presents multidimensional negative impacts on the life of dysphagic patients and may generate decision conflicts related to their diet. This is a review of the literature on speech-language therapy, decision conflicts and the agents involved in the decision making process for deliberations related to the nutrition of this type of patient. This is an exploratory and descriptive study, with content analysis as proposed by Bardin. The databases used were PubMed, Scopus, Web of Science, Cochrane, Embase and Virtual Health Library. Conflicts involving the speech-language therapist, the patient, the family and the multidisciplinary team were identified. In the selected articles, no theory or method was identified to support the mediation of these conflicts. No Brazilian publications that answered the guiding question were found.
DOI: 10.6084/m9.figshare.19905434.v1
title: Speech therapy, decision conflicts and dysphagic patients: an integrative review

description: Abstract Dysphagia presents multidimensional negative impacts on the life of dysphagic patients and may generate decision conflicts related to their diet. This is a review of the literature on speech-language therapy, decision conflicts and the agents involved in the decision making process for deliberations related to the nutrition of this type of patient. This is an exploratory and descriptive study, with content analysis as proposed by Bardin. The databases used were PubMed, Scopus, Web of Science, Cochrane, Embase and Virtual Health Library. Conflicts involving the speech-language therapist, the patient, the family and the multidisciplinary team were identified. In the selected articles, no theory or method was identified to support the mediation of these conflicts. No Brazilian publications that answered the guiding question were found.
DOI: 10.6084/m9.figshare.19905443
title: Care pathway of patients living with lung cancer

description: Abstract This article analyzes the feelings and difficulties of lung cancer patients and their families regarding diagnostic and therapeutic itineraries. This is qualitative research with focus group of patient/family dyads. Two categories of analysis stood out: ‘Pathway start and Diagnosis’ and ‘In search of treatment: barriers’. The difficulty of diagnosis is discussed due to the lack of infrastructure of services, scarce financial resources of patients, inadequate public health network and unpreparedness for diagnosis. After diagnosis, we present the path in search of treatment and the financial, geographical, structural and work process barriers in public health. Patients in small municipalities or rural areas face more difficulties in accessing health services. We conclud that the care pathway in the public sector is influenced by health inequalities and vulnerabilities, reflecting less access to services and delayed diagnosis and treatment of the disease.
DOI: 10.6084/m9.figshare.19905443.v1
title: Care pathway of patients living with lung cancer

description: Abstract This article analyzes the feelings and difficulties of lung cancer patients and their families regarding diagnostic and therapeutic itineraries. This is qualitative research with focus group of patient/family dyads. Two categories of analysis stood out: ‘Pathway start and Diagnosis’ and ‘In search of treatment: barriers’. The difficulty of diagnosis is discussed due to the lack of infrastructure of services, scarce financial resources of patients, inadequate public health network and unpreparedness for diagnosis. After diagnosis, we present the path in search of treatment and the financial, geographical, structural and work process barriers in public health. Patients in small municipalities or rural areas face more difficulties in accessing health services. We conclud that the care pathway in the public sector is influenced by health inequalities and vulnerabilities, reflecting less access to services and delayed diagnosis and treatment of the disease.
DOI: 10.35077/moo
title: 596096

description: This is a series of monosynaptic, retrograde trans-synaptic tracing images of whole mouse brain to map whole-brain inputs to genetically-identified cell populations brain-wide.
description: DATASET METADATA: title:'596096', GeneralModality:'connectivity', Technique:'retrograde transsynaptic tracing' SPECIMEN METADATA: LocalID:'596096', Species:'Mouse', NCBITaxonomy:'NCBI:txid10090', Age:'86.0', Ageunit:'Days', Sex:'Male', Genotype:'Rbp4-Cre_KL100/wt', OrganLocalID:'1131168807.0', OrganName:'Brain', SampleLocalID:'0539070524' INSTRUMENT METADATA: MicroscopeType:'Two Photon', MicroscopeManufacturerAndModel:'TissueVision TissueCyte 1000', ObjectiveName:'Zeiss 20X Plan-Apochromat', ObjectiveImmersion:'Water', ObjectiveNA:'1.0', ObjectiveMagnification:'20X', DetectorType:'PMT', DetectorModel:'Hamamatsu R3896', IlluminationWavelength:'925nm', DetectionWavelength:'447-593nm', SampleTemperature:'20.0' IMAGE METADATA: xAxis:'left-to-right', yAxis:'superior-to-inferior', zAxis:'posterior-to-anterior', Number:'1,2,3,red,green,blue', displayColor:'(1.0,0.0,0.0),(0.0,1.0,0.0),(0.0,0.0,1.0)', Representation:'neurite', Flurophore:'CH1(background fluorescence) CH2(GFP) CH3(background fluorescence)', stepSizeX:'0.875', stepSizeY:'0.875', stepSizeZ:'100.0', Channels:'3.0', Slices:'140.0', z:'1.0', Xsize:'16000.0', Ysize:'12000.0', Zsize:'1.0'
DOI: 10.5281/zenodo.6587517
title: Cacatua alba decontaminated FSCR

description: .
DOI: 10.5281/zenodo.6587516
title: Cacatua alba decontaminated FSCR

description: .
DOI: 10.6084/m9.figshare.16487318
title: Molecular characterization of Blastocystis subtypes isolated in the city of Uberaba, Minas Gerais State, Brazil

description: Abstract INTRODUCTION Blastocystis is an intestinal protozoan that may play a role in the pathogenicity of humans. This study aimed to (i) genetically characterize Blastocystis isolates obtained from human fecal samples and the water supply of the city of Uberaba, Minas Gerais, Brazil, and (ii) to verify the phylogenetic relationship between these isolates. METHODS Blastocystis species present in 26 fecal samples obtained from humans and animals from Uberaba were genetically characterized by polymerase chain reaction-restriction fragment length polymorphism and polymerase chain reaction-sequence-tagged sites. All amplicons were partially sequenced and/or defined according to the GenBank classification. RESULTS Polymerase chain reaction amplicons were generated from 21 human isolates and 18 water samples. The subtypes defined were ST1 (53.3%), ST3 (40.0%), and ST2 (6.7%) for human isolates; ST10 (100%) for bovine isolates; and ST5 (50.0%), ST1 (25%), and ST3 (25%) for pigs. Sequencing of polymerase chain reaction products showed a 98%-99% identity for the Blastocystis sequences deposited in GenBank, except for sequences from water samples that showed the identity of algae sequences. Phylogenetic analysis of Blastocystis sequences showed two distinct groups, one of which was principally formed by ST1, ST5, and ST10, and the other by isolates characterized as ST3 and ST7. Both clades showed human and animal sequences, reinforcing the notion that Blastocystis subtypes are not host-specific. CONCLUSIONS The data showed that Blastocystis subtypes circulating in Uberaba are ST1-ST3, ST5, and ST10, present in both humans and animals, demonstrating that the Blastocystis subtypes are not host-specific; that is, zoonotic transmission is possible.
DOI: 10.6084/m9.figshare.16487318.v1
title: Molecular characterization of Blastocystis subtypes isolated in the city of Uberaba, Minas Gerais State, Brazil

description: Abstract INTRODUCTION Blastocystis is an intestinal protozoan that may play a role in the pathogenicity of humans. This study aimed to (i) genetically characterize Blastocystis isolates obtained from human fecal samples and the water supply of the city of Uberaba, Minas Gerais, Brazil, and (ii) to verify the phylogenetic relationship between these isolates. METHODS Blastocystis species present in 26 fecal samples obtained from humans and animals from Uberaba were genetically characterized by polymerase chain reaction-restriction fragment length polymorphism and polymerase chain reaction-sequence-tagged sites. All amplicons were partially sequenced and/or defined according to the GenBank classification. RESULTS Polymerase chain reaction amplicons were generated from 21 human isolates and 18 water samples. The subtypes defined were ST1 (53.3%), ST3 (40.0%), and ST2 (6.7%) for human isolates; ST10 (100%) for bovine isolates; and ST5 (50.0%), ST1 (25%), and ST3 (25%) for pigs. Sequencing of polymerase chain reaction products showed a 98%-99% identity for the Blastocystis sequences deposited in GenBank, except for sequences from water samples that showed the identity of algae sequences. Phylogenetic analysis of Blastocystis sequences showed two distinct groups, one of which was principally formed by ST1, ST5, and ST10, and the other by isolates characterized as ST3 and ST7. Both clades showed human and animal sequences, reinforcing the notion that Blastocystis subtypes are not host-specific. CONCLUSIONS The data showed that Blastocystis subtypes circulating in Uberaba are ST1-ST3, ST5, and ST10, present in both humans and animals, demonstrating that the Blastocystis subtypes are not host-specific; that is, zoonotic transmission is possible.
DOI: 10.35077/mop
title: 596240

description: This is a series of monosynaptic, retrograde trans-synaptic tracing images of whole mouse brain to map whole-brain inputs to genetically-identified cell populations brain-wide.
description: DATASET METADATA: title:'596240', GeneralModality:'connectivity', Technique:'retrograde transsynaptic tracing' SPECIMEN METADATA: LocalID:'596240', Species:'Mouse', NCBITaxonomy:'NCBI:txid10090', Age:'85.0', Ageunit:'Days', Sex:'Male', Genotype:'Tlx3-Cre_PL56/wt', OrganLocalID:'1131348960.0', OrganName:'Brain', SampleLocalID:'0539070434' INSTRUMENT METADATA: MicroscopeType:'Two Photon', MicroscopeManufacturerAndModel:'TissueVision TissueCyte 1000', ObjectiveName:'Zeiss 20X Plan-Apochromat', ObjectiveImmersion:'Water', ObjectiveNA:'1.0', ObjectiveMagnification:'20X', DetectorType:'PMT', DetectorModel:'Hamamatsu R3896', IlluminationWavelength:'925nm', DetectionWavelength:'447-593nm', SampleTemperature:'20.0' IMAGE METADATA: xAxis:'left-to-right', yAxis:'superior-to-inferior', zAxis:'posterior-to-anterior', Number:'1,2,3,red,green,blue', displayColor:'(1.0,0.0,0.0),(0.0,1.0,0.0),(0.0,0.0,1.0)', Representation:'neurite', Flurophore:'CH1(background fluorescence) CH2(GFP) CH3(background fluorescence)', stepSizeX:'0.875', stepSizeY:'0.875', stepSizeZ:'100.0', Channels:'3.0', Slices:'140.0', z:'1.0', Xsize:'16000.0', Ysize:'12000.0', Zsize:'1.0'
DOI: 10.6084/m9.figshare.19905463
title: Nephrotic syndrome associated with primary atypical hemolytic uremic syndrome

description: Abstract Primary atypical hemolytic-uremic syndrome is a rare disease characterized by non-immune microangiopathic hemolytic anemia, thrombocytopenia, and renal dysfunction; it is related to alterations in the regulation of the alternative pathway of complement due to genetic mutations. The association with nephrotic syndrome is unusual. We present here a pediatric patient diagnosed with primary atypical hemolytic-uremic syndrome associated with nephrotic syndrome who responded to eculizumab treatment.
DOI: 10.6084/m9.figshare.19905463.v1
title: Nephrotic syndrome associated with primary atypical hemolytic uremic syndrome

description: Abstract Primary atypical hemolytic-uremic syndrome is a rare disease characterized by non-immune microangiopathic hemolytic anemia, thrombocytopenia, and renal dysfunction; it is related to alterations in the regulation of the alternative pathway of complement due to genetic mutations. The association with nephrotic syndrome is unusual. We present here a pediatric patient diagnosed with primary atypical hemolytic-uremic syndrome associated with nephrotic syndrome who responded to eculizumab treatment.
DOI: 10.6084/m9.figshare.19905464
title: Comparative analysis of kidney transplant costs related to recovery of renal function after the procedure

description: Abstract Introduction: The number of kidney transplants (KTx) is increasing in Brazil and, consequently, the costs of this procedure increase the country's health budget. We retrospectively evaluated the data of kidney transplant procedures until hospital discharge, according to kidney function recovery after the procedure. Methods: Retrospective analysis of the non-sensitized, 1st KTx from deceased donors performed between Jan/2010 to Dec/2017. Results: Out of the 1300 KTx from deceased donors performed in this period, 730 patients were studied and divided into 3 groups: Immediate Renal Function (IRF) - decrease in serum creatinine ≥ 10% on two consecutive days; Delayed Graft Function (DGF) - decrease in serum creatinine &lt;10% on two consecutive days, without the need for dialysis, and Dialysis (D) - need for dialysis during the first week. Patients in group D stayed longer in the hospital compared to DGF and IRF (21, 11 and 8 days respectively, p &lt; 0.001). More D patients (21%) were admitted to the ICU and performed a greater number of laboratory tests (p &lt; 0.001) and renal biopsies (p &lt; 0.001), in addition to receiving a higher amount of immunosuppressants. Total hospital costs were higher in group D and DGF compared to IRF (U$ 7.021,48; U$ 3.603,42 and U$ 2.642,37 respectively, p &lt; 0.001). Conclusion: The costs of the transplant procedure is impacted by the recovery of kidney function after the transplant. The reimbursement for each of these different kidney function outcomes should be individualized in order to cover their real costs.
DOI: 10.6084/m9.figshare.19905464.v1
title: Comparative analysis of kidney transplant costs related to recovery of renal function after the procedure

description: Abstract Introduction: The number of kidney transplants (KTx) is increasing in Brazil and, consequently, the costs of this procedure increase the country's health budget. We retrospectively evaluated the data of kidney transplant procedures until hospital discharge, according to kidney function recovery after the procedure. Methods: Retrospective analysis of the non-sensitized, 1st KTx from deceased donors performed between Jan/2010 to Dec/2017. Results: Out of the 1300 KTx from deceased donors performed in this period, 730 patients were studied and divided into 3 groups: Immediate Renal Function (IRF) - decrease in serum creatinine ≥ 10% on two consecutive days; Delayed Graft Function (DGF) - decrease in serum creatinine &lt;10% on two consecutive days, without the need for dialysis, and Dialysis (D) - need for dialysis during the first week. Patients in group D stayed longer in the hospital compared to DGF and IRF (21, 11 and 8 days respectively, p &lt; 0.001). More D patients (21%) were admitted to the ICU and performed a greater number of laboratory tests (p &lt; 0.001) and renal biopsies (p &lt; 0.001), in addition to receiving a higher amount of immunosuppressants. Total hospital costs were higher in group D and DGF compared to IRF (U$ 7.021,48; U$ 3.603,42 and U$ 2.642,37 respectively, p &lt; 0.001). Conclusion: The costs of the transplant procedure is impacted by the recovery of kidney function after the transplant. The reimbursement for each of these different kidney function outcomes should be individualized in order to cover their real costs.
DOI: 10.6084/m9.figshare.16485422
title: Trends in primary multidrug-resistant tuberculosis in the State of Rio de Janeiro: a retrospective study conducted during 2000-2019

description: Abstract INTRODUCTION: We analyzed the trends in primary multidrug-resistant tuberculosis (MDR-TB). METHODS: We performed a time series analysis of primary MDR-TB cases reported in the State of Rio de Janeiro (RJ) during 2000-2019. The annual percent change and the average annual percentage change (AAPC) were computed using joinpoint regression analysis. RESULTS: The percentage of cases increased from 7.69% in 2000 to 38.42% in 2018. We observed an upward trend during this period (AAPC = 9.4; 95% confidence interval 1.4-18.0, p &lt; 0.001). CONCLUSIONS: The trend indicates the increasing occurrence of MDR-TB transmission sources in RJ during 2000-2019.
DOI: 10.6084/m9.figshare.16485422.v1
title: Trends in primary multidrug-resistant tuberculosis in the State of Rio de Janeiro: a retrospective study conducted during 2000-2019

description: Abstract INTRODUCTION: We analyzed the trends in primary multidrug-resistant tuberculosis (MDR-TB). METHODS: We performed a time series analysis of primary MDR-TB cases reported in the State of Rio de Janeiro (RJ) during 2000-2019. The annual percent change and the average annual percentage change (AAPC) were computed using joinpoint regression analysis. RESULTS: The percentage of cases increased from 7.69% in 2000 to 38.42% in 2018. We observed an upward trend during this period (AAPC = 9.4; 95% confidence interval 1.4-18.0, p &lt; 0.001). CONCLUSIONS: The trend indicates the increasing occurrence of MDR-TB transmission sources in RJ during 2000-2019.
DOI: 10.6084/m9.figshare.16486782
title: Determining the proper sowing time for the mixture of Hungarian vetch and triticale under continental climate conditions

description: ABSTRACT: The research was conducted to determine forage yield and some quality characteristics of Hungarian vetch + triticale mixture, sowed in five different times under rainfed conditions of Central Anatolia, Turkey. The mixture was sowed in the second, third and fourth week of October, and the first and the second week of November in 2017 and 2018. Depending on the sowing times, plant height (PH) of Hungarian vetch and triticale was between 46.7 and 59.4 cm, and 85.9 and 93.4 cm, respectively. Green forage yield (GFY) was between 1746.2 and 2059.4 kg da-1, dry matter yield (DMY) was between 541.0 and 707.6 kg da-1, crude protein yield (CPY) was between 80.4 and 110.3 kg da-1, digestible dry matter yield (DDMY) was between 340.8 and 453.9 kg da-1, acid detergent fiber (ADF) ratio was between 31.8 and 33.7%, neutral detergent fiber (NDF) ratio was between 44.7 and 49.5%, total digestible nutrient (TDN) was between 57.9 and 60.4% and relative feed value (RFV) was between 118.6 and 133.8. Sowing time had a significant effect (P &lt; 0.05) on PH of triticale, while it has a very significant effect (P &lt; 0.01) on GFY, DMY, CPY, DDMY, NDF ratios and RFV. Delaying the sowing time caused a decrease in the GFY, DMY and quality of the mixture. Results revealed that the first week of October is the most appropriate sowing time to obtain high dry matter yield with high quality under continental climate conditions of the Central Anatolia.
DOI: 10.6084/m9.figshare.16486782.v1
title: Determining the proper sowing time for the mixture of Hungarian vetch and triticale under continental climate conditions

description: ABSTRACT: The research was conducted to determine forage yield and some quality characteristics of Hungarian vetch + triticale mixture, sowed in five different times under rainfed conditions of Central Anatolia, Turkey. The mixture was sowed in the second, third and fourth week of October, and the first and the second week of November in 2017 and 2018. Depending on the sowing times, plant height (PH) of Hungarian vetch and triticale was between 46.7 and 59.4 cm, and 85.9 and 93.4 cm, respectively. Green forage yield (GFY) was between 1746.2 and 2059.4 kg da-1, dry matter yield (DMY) was between 541.0 and 707.6 kg da-1, crude protein yield (CPY) was between 80.4 and 110.3 kg da-1, digestible dry matter yield (DDMY) was between 340.8 and 453.9 kg da-1, acid detergent fiber (ADF) ratio was between 31.8 and 33.7%, neutral detergent fiber (NDF) ratio was between 44.7 and 49.5%, total digestible nutrient (TDN) was between 57.9 and 60.4% and relative feed value (RFV) was between 118.6 and 133.8. Sowing time had a significant effect (P &lt; 0.05) on PH of triticale, while it has a very significant effect (P &lt; 0.01) on GFY, DMY, CPY, DDMY, NDF ratios and RFV. Delaying the sowing time caused a decrease in the GFY, DMY and quality of the mixture. Results revealed that the first week of October is the most appropriate sowing time to obtain high dry matter yield with high quality under continental climate conditions of the Central Anatolia.
DOI: 10.35077/mud
title: 595406

description: This is a series of monosynaptic, retrograde trans-synaptic tracing images of whole mouse brain to map whole-brain inputs to genetically-identified cell populations brain-wide.
description: DATASET METADATA: title:'595406', GeneralModality:'connectivity', Technique:'retrograde transsynaptic tracing' SPECIMEN METADATA: LocalID:'595406', Species:'Mouse', NCBITaxonomy:'NCBI:txid10090', Age:'104.0', Ageunit:'Days', Sex:'Female', Genotype:'Ctgf-T2A-dgCre/wt', OrganLocalID:'1132237619.0', OrganName:'Brain', SampleLocalID:'0539070476' INSTRUMENT METADATA: MicroscopeType:'Two Photon', MicroscopeManufacturerAndModel:'TissueVision TissueCyte 1000', ObjectiveName:'Zeiss 20X Plan-Apochromat', ObjectiveImmersion:'Water', ObjectiveNA:'1.0', ObjectiveMagnification:'20X', DetectorType:'PMT', DetectorModel:'Hamamatsu R3896', IlluminationWavelength:'925nm', DetectionWavelength:'447-593nm', SampleTemperature:'20.0' IMAGE METADATA: xAxis:'left-to-right', yAxis:'superior-to-inferior', zAxis:'posterior-to-anterior', Number:'1,2,3,red,green,blue', displayColor:'(1.0,0.0,0.0),(0.0,1.0,0.0),(0.0,0.0,1.0)', Representation:'neurite', Flurophore:'CH1(background fluorescence) CH2(GFP) CH3(background fluorescence)', stepSizeX:'0.875', stepSizeY:'0.875', stepSizeZ:'100.0', Channels:'3.0', Slices:'140.0', z:'1.0', Xsize:'16000.0', Ysize:'12000.0', Zsize:'1.0'