cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.57760/sciencedb.xbyxb.00039
title: Supplementary Figure S1 GSEA and ssGSEA analysis
title: Supplementary Figure S1 GSEA and ssGSEA analysis

description: Bubble plots exhibited the top-ranked GSEA results for the top-ranked KEGG pathways in (A) recurrent POP compared with primary POP uterosacral ligaments, and (B) recurrent POP compared with non-POP uterosacral ligaments. The classic GSEA plots showed that both adipose- and inflammation-related pathways were activated in the two contrast matrices for (C) recurrent POP vs.vs primary POP uterosacral ligaments, and (D) recurrent POP vs.vs non-POP uterosacral ligaments. Heatmaps showed hierarchical clustering of ssGSEA scores of KEGG pathways differentially enriched in (E) recurrent POP vs.vs primary POP uterosacral ligaments and (F) recurrent POP vs.vs non-POP uterosacral ligaments. (G) Spearman correlation analysis of pathway ssGSEA scores revealed that PPAR signaling pathways was strongly associated with adipose- and inflammation-related pathways in non-POP, primary POP and recurrent POP uterosacral ligaments. GSEA, g: Gene set enrichment analysis; ssGSEA, the s: Single-sample gene set enrichment analysis; POP, p: Pelvic organ prolapses; NES, n: Normalized enrichment scores.
description: Bubble plots exhibited the top-ranked GSEA results for the top-ranked KEGG pathways in (A) recurrent POP compared with primary POP uterosacral ligaments, and (B) recurrent POP compared with non-POP uterosacral ligaments. The classic GSEA plots showed that both adipose- and inflammation-related pathways were activated in the two contrast matrices for (C) recurrent POP vs.vs primary POP uterosacral ligaments, and (D) recurrent POP vs.vs non-POP uterosacral ligaments. Heatmaps showed hierarchical clustering of ssGSEA scores of KEGG pathways differentially enriched in (E) recurrent POP vs.vs primary POP uterosacral ligaments and (F) recurrent POP vs.vs non-POP uterosacral ligaments. (G) Spearman correlation analysis of pathway ssGSEA scores revealed that PPAR signaling pathways was strongly associated with adipose- and inflammation-related pathways in non-POP, primary POP and recurrent POP uterosacral ligaments. GSEA, g: Gene set enrichment analysis; ssGSEA, the s: Single-sample gene set enrichment analysis; POP, p: Pelvic organ prolapses; NES, n: Normalized enrichment scores.
DOI: 10.57760/sciencedb.16468
title: Taurine alleviates osteoarthritis in mice mediated by gut microbiota dysbiosis
title: 牛磺酸缓解肠道微生物群失调介导的小鼠骨关节炎

description: We're uncovering more about the link between gut microbiota dysbiosis (GMD) and osteoarthritis (OA), but we're still in the dark about the full connection and mechanisms between the two. What we've found here is that mice with GMD show clear signs of osteoarthritis in their knee joints. We further validated through a gut microbiota dysbiosis mouse model that gut microbiota dysbiosis can mediate susceptibility to osteoarthritis in mice, and this susceptibility can be transferred through microbiota transplantation. Subsequent metabolomics analysis revealed that the downregulation of Taurine levels in the bodies of osteoarthritis mice may be the “culprit” behind OA progression. Further research indicates that Taurine can alleviate gut microbiota dysbiosis-induced osteoarthritis in mice and mitigate damage to cartilage cells through the ROS/NF-κB axis. Our research findings provide ample evidence for the "gut-joint axis" and demonstrate that taurine could serve as a potential therapeutic target for gut microbiota dysbiosis-induced osteoarthritis.
description: We're uncovering more about the link between gut microbiota dysbiosis (GMD) and osteoarthritis (OA), but we're still in the dark about the full connection and mechanisms between the two. What we've found here is that mice with GMD show clear signs of osteoarthritis in their knee joints. We further validated through a gut microbiota dysbiosis mouse model that gut microbiota dysbiosis can mediate susceptibility to osteoarthritis in mice, and this susceptibility can be transferred through microbiota transplantation. Subsequent metabolomics analysis revealed that the downregulation of Taurine levels in the bodies of osteoarthritis mice may be the “culprit” behind OA progression. Further research indicates that Taurine can alleviate gut microbiota dysbiosis-induced osteoarthritis in mice and mitigate damage to cartilage cells through the ROS/NF-κB axis. Our research findings provide ample evidence for the "gut-joint axis" and demonstrate that taurine could serve as a potential therapeutic target for gut microbiota dysbiosis-induced osteoarthritis.
DOI: 10.57760/sciencedb.partic.00112
title: Study of hydraulic transport characteristics and erosion wear of twisted four-lobed pipe based on CFD-DEM
title: Study of hydraulic transport characteristics and erosion wear of twisted four-lobed pipe based on CFD-DEM

description: Pipeline hydraulic transportation is extensively utilized across diverse sectors, with enhancing the performance of pipeline hydrodynamic transport and minimizing erosion wear on the pipeline walls being essential for ensuring the stability of pipeline operations. This paper introduces a methodology for the hydraulic transport of a twisted four-lobed pipe, employing a numerical and erosion model developed through the CFD-DEM (computational fluid dynamics and discrete element method) coupling approach. An experimental circulating flow platform is constructed for validation purposes. The performance of the pipe is assessed by analyzing key indices including fluid velocity, pressure drop, particle trajectory, and erosion wear. The results indicate that twisted four-lobed pipe enhances fluid flow rates, facilitating particle discharge and mitigating accumulation, with reduced wear compared to the twin twist triangle spiral pipe. The analysis of structural parameters’ impact on hydraulic conveyance is also presented. These findings offer theoretical insights for optimizing pipeline performance in hydraulic conveyance while minimizing wear.
description: Pipeline hydraulic transportation is extensively utilized across diverse sectors, with enhancing the performance of pipeline hydrodynamic transport and minimizing erosion wear on the pipeline walls being essential for ensuring the stability of pipeline operations. This paper introduces a methodology for the hydraulic transport of a twisted four-lobed pipe, employing a numerical and erosion model developed through the CFD-DEM (computational fluid dynamics and discrete element method) coupling approach. An experimental circulating flow platform is constructed for validation purposes. The performance of the pipe is assessed by analyzing key indices including fluid velocity, pressure drop, particle trajectory, and erosion wear. The results indicate that twisted four-lobed pipe enhances fluid flow rates, facilitating particle discharge and mitigating accumulation, with reduced wear compared to the twin twist triangle spiral pipe. The analysis of structural parameters’ impact on hydraulic conveyance is also presented. These findings offer theoretical insights for optimizing pipeline performance in hydraulic conveyance while minimizing wear.
DOI: 10.57760/sciencedb.psych.00336
title: Effects of target response and distraction inhibition on recognition
title: 目标反应与分心抑制对再认提取的影响

description: This experiment was conducted in a standard psychological laboratory. This program was written using e-prime2.0 pro software. The computer used in the experiment was a Lenovo Thinkpad desktop computer, with a 19-inch LCD color screen and a resolution of 1280 × 1024 pixels. The background of the computer during the experiment was black, and the words were white.The dataset includes the final data from experiments 123, primarily in SPSS format. 
description: This experiment was conducted in a standard psychological laboratory. This program was written using e-prime2.0 pro software. The computer used in the experiment was a Lenovo Thinkpad desktop computer, with a 19-inch LCD color screen and a resolution of 1280 × 1024 pixels. The background of the computer during the experiment was black, and the words were white.The dataset includes the final data from experiments 123, primarily in SPSS format.
DOI: 10.57760/sciencedb.16476
title: Supplementary Figure S2 Microenvironment analysis for uterosacral ligaments
title: Supplementary Figure S2 Microenvironment analysis for uterosacral ligaments

description: Supplementary Figure S2  Microenvironment analysis for uterosacral ligaments (A) Cell composition of the microenvironment in non-POP, primary POP, and recurrent POP uterosacral ligaments was calculated by the xCell method. (B) Spearman analysis using the xCell scores revealed a significant positive correlation between the enrichment of adipocytes and the enrichment of inflammation-related immune cells (monocytes and neutrophils) in the uterosacral ligaments. (C) Spearman analysis showed the correlation between core DEGs’" expression and xCell scores of adipocytes, monocytes, and neutrophils in the uterosacral ligaments. (D) Spearman analysis displayed the correlation between xCell scores of microenvironment cells and enrichment scores of the PPAR signaling pathway in the uterosacral ligaments. *P-value P&lt;0.05; ns, not significant; POP, pelvic organ prolapses.
description: Supplementary Figure S2  Microenvironment analysis for uterosacral ligaments (A) Cell composition of the microenvironment in non-POP, primary POP, and recurrent POP uterosacral ligaments was calculated by the xCell method. (B) Spearman analysis using the xCell scores revealed a significant positive correlation between the enrichment of adipocytes and the enrichment of inflammation-related immune cells (monocytes and neutrophils) in the uterosacral ligaments. (C) Spearman analysis showed the correlation between core DEGs’" expression and xCell scores of adipocytes, monocytes, and neutrophils in the uterosacral ligaments. (D) Spearman analysis displayed the correlation between xCell scores of microenvironment cells and enrichment scores of the PPAR signaling pathway in the uterosacral ligaments. *P-value P&lt;0.05; ns, not significant; POP, pelvic organ prolapses.
DOI: 10.57760/sciencedb.16491
title: Content analysis of China's quantum industry policy
title: 中国量子产业政策文本分析

description: content analysis related to China's quantum industry from 2001 to 2023 
description: content analysis related to China's quantum industry from 2001 to 2023
DOI: 10.57760/sciencedb.16497
title: Ultra-broadband all-optical nonlinear activation function enabled by MoTe2/optical waveguide integrated devices
title: Ultra-broadband all-optical nonlinear activation function enabled by MoTe2/optical waveguide integrated devices

description: All-optical nonlinear activation functions (NAFs) are crucial for enabling rapid optical neural networks (ONNs). As linear matrix computation advances in integrated ONNs, on-chip all-optical NAFs face challenges such as limited integration, high latency, substantial power consumption, and a high activation threshold. In this work, we develop a new integrated nonlinear optical activator based on the butt-coupling integration of two-dimensional (2D) material and optical waveguides (OWGs). The activator exhibits an ultra-broadband response from visible to near-infrared wavelength, a low activation threshold of 0.94 μW, a small device size (~50 µm2), an ultra-fast response rate (2.08 THz), and high-density integration. The excellent nonlinear effects and broadband response of 2D materials have been utilized to create all-optical NAFs. These activators were applied to simulate MNIST handwritten digit recognition, achieving an accuracy of 97.6%. The results underscore the potential application of this approach in ONNs. Moreover, the classification of more intricate CIFAR-10 images demonstrated a generalizable accuracy of 94.6%. The present nonlinear activator promises a new general platform for three-dimensional (3D) ultra-broadband ONNs with dense integration and low activation threshold by integrating a variety of strong nonlinear optical (NLO) materials (e.g., 2D materials) and OWGs in glass.
description: All-optical nonlinear activation functions (NAFs) are crucial for enabling rapid optical neural networks (ONNs). As linear matrix computation advances in integrated ONNs, on-chip all-optical NAFs face challenges such as limited integration, high latency, substantial power consumption, and a high activation threshold. In this work, we develop a new integrated nonlinear optical activator based on the butt-coupling integration of two-dimensional (2D) material and optical waveguides (OWGs). The activator exhibits an ultra-broadband response from visible to near-infrared wavelength, a low activation threshold of 0.94 μW, a small device size (~50 µm2), an ultra-fast response rate (2.08 THz), and high-density integration. The excellent nonlinear effects and broadband response of 2D materials have been utilized to create all-optical NAFs. These activators were applied to simulate MNIST handwritten digit recognition, achieving an accuracy of 97.6%. The results underscore the potential application of this approach in ONNs. Moreover, the classification of more intricate CIFAR-10 images demonstrated a generalizable accuracy of 94.6%. The present nonlinear activator promises a new general platform for three-dimensional (3D) ultra-broadband ONNs with dense integration and low activation threshold by integrating a variety of strong nonlinear optical (NLO) materials (e.g., 2D materials) and OWGs in glass.
DOI: 10.57760/sciencedb.16499
title: Raw data
title: Raw data

description: The data are generated from the research we conducted on rats treated with methylmercury
description: The data are generated from the research we conducted on rats treated with methylmercury
DOI: 10.57760/sciencedb.16506
title: Cerebral ischemia transcriptome sequencing
title: 脑缺血转录组测序

description: Transcriptome sequencing of cerebral ischemia in WT and KO mice
description: Transcriptome sequencing of cerebral ischemia in WT and KO mice
DOI: 10.57760/sciencedb.16510
title: cigar macrobiotics
title: 雪茄基因

description: 原始数据为 Illumina fastq 格式，首先对原始数据进行切分、质量切割等操作，如果是宿主体内或宿主表面的微生物，则同时进行宿主污染等操作。获得的序列为有效数据，使用剪接软件进行剪接组装，并进行基因预测。对预测基因进行注释和分类，包括NR、KEGG、eggNOG等。同时，获得每个样品中物种的相对丰度，并在此基础上进行样品相似性聚类、测序检验和差异统计比较。
description: 原始数据为 Illumina fastq 格式，首先对原始数据进行切分、质量切割等操作，如果是宿主体内或宿主表面的微生物，则同时进行宿主污染等操作。获得的序列为有效数据，使用剪接软件进行剪接组装，并进行基因预测。对预测基因进行注释和分类，包括NR、KEGG、eggNOG等。同时，获得每个样品中物种的相对丰度，并在此基础上进行样品相似性聚类、测序检验和差异统计比较。
DOI: 10.57760/sciencedb.16529
title: RNA-seq of SCLC cells after treatment of cisplatin and disulfiram
title: RNA-seq of SCLC cells after treatment of cisplatin and disulfiram

description: Small cell lung cancer H69 cells were treated with DMSO control, 2 μM Cisplastin, 0.025 μM Disulfiram, and Cisplastin combined with Disulfiram for 24 hours. Total RNA was extracted using RNA Easy Fast Tissue/cell Kit (Tiangen, Beijing, China). Enrich mRNA using VAHTS mRNA Capture Beads (Vazyme, Jiangsu, China). Prepare the library using the VAHTS Universal V8 RNA Seq Library Prep Kit (Vazyme, Jiangsu, China), and then perform paired end sequencing on the Illumina NovaSeq 6000 machine (Illumina, CA, USA) to generate 150 bp paired end reads. Trim the original reading using Trim Galore (v0.6.7) to remove low-quality readings. Then, clean reads were aligned with the GRCh37 genome using STAR (v2.7.10b) and quantified using RSEM (v1.3.1). 
description: Small cell lung cancer H69 cells were treated with DMSO control, 2 μM Cisplastin, 0.025 μM Disulfiram, and Cisplastin combined with Disulfiram for 24 hours. Total RNA was extracted using RNA Easy Fast Tissue/cell Kit (Tiangen, Beijing, China). Enrich mRNA using VAHTS mRNA Capture Beads (Vazyme, Jiangsu, China). Prepare the library using the VAHTS Universal V8 RNA Seq Library Prep Kit (Vazyme, Jiangsu, China), and then perform paired end sequencing on the Illumina NovaSeq 6000 machine (Illumina, CA, USA) to generate 150 bp paired end reads. Trim the original reading using Trim Galore (v0.6.7) to remove low-quality readings. Then, clean reads were aligned with the GRCh37 genome using STAR (v2.7.10b) and quantified using RSEM (v1.3.1).
DOI: 10.57760/sciencedb.16543
title: net cage
title: net cage

description: 综合分析 显示优化拖曳长度、系泊位置和拖曳速度 准确评估波期和高度，对于确保 海上网箱湿拖作业的安全性。本研究提供 增强 深海水产养殖设备的运输。 
description: 综合分析 显示优化拖曳长度、系泊位置和拖曳速度 准确评估波期和高度，对于确保 海上网箱湿拖作业的安全性。本研究提供 增强 深海水产养殖设备的运输。
DOI: 10.57760/sciencedb.16550
title: Supplementary material for manuscript "Recurring Glacial Activity at Martian Mid-latitudes Evidenced by Characterizing Double Layered Ejecta (DLE) Craters"
title: Supplementary material for manuscript "Recurring Glacial Activity at Martian Mid-latitudes Evidenced by Characterizing Double Layered Ejecta (DLE) Craters"

description: This supplement materials provides information on the properties of the DLE craters, as well as dating results and related data (see “PDF” document). In addition, the dating-related “scc” files are also provided (see the compressed package “Data S1”).
description: This supplement materials provides information on the properties of the DLE craters, as well as dating results and related data (see “PDF” document). In addition, the dating-related “scc” files are also provided (see the compressed package “Data S1”).
DOI: 10.57760/sciencedb.16526
title: The small RNA-sequencing data for virus-infected bat and human cells
title: The small RNA-sequencing data for virus-infected bat and human cells

description: We examined if infections by diverse RNA viruses can trigger the production of vsiRNAs in multiple cell lines derived from different bat species. To this end, we infected multiple bat cells with two positive-stranded RNA viruses, enterovirus A71 (EV-A71) and Dengue virus-2 (DENV2), and two negative-stranded RNA viruses, Nipah virus (NiV) and Ebola virus (EBOV), all of which have been reported to naturally infect bats.
description: We examined if infections by diverse RNA viruses can trigger the production of vsiRNAs in multiple cell lines derived from different bat species. To this end, we infected multiple bat cells with two positive-stranded RNA viruses, enterovirus A71 (EV-A71) and Dengue virus-2 (DENV2), and two negative-stranded RNA viruses, Nipah virus (NiV) and Ebola virus (EBOV), all of which have been reported to naturally infect bats.
DOI: 10.57760/sciencedb.16559
title: The sequences of the TA-cloned PCR products for the validation of Insertion sequences associated with xenobiotic degradation genes.
title: The sequences of the TA-cloned PCR products for the validation of Insertion sequences associated with xenobiotic degradation genes.

description: This dataset contains the sequences of TA-cloned PCR products for the validation of IS.XDG-Chip. This chip is a high-throughput quantitative PCR (HT-qPCR) platform designed to detect and quantify xenobiotic degradation genes (XDGs) in diverse environmental samples. A total of 9 primer sets were validated for their high specificity. The universal primers barcoding bacterial 16S rRNA gene were included as a reference gene of IS.XDG-Chip. Specific primers were designed for each target gene, followed by PCR amplification. Amplicons displaying single bands of the expected fragment size were selected and subjected to T-A cloning. For each target, ten clones were randomly selected for Sanger sequencing. 
description: This dataset contains the sequences of TA-cloned PCR products for the validation of IS.XDG-Chip. This chip is a high-throughput quantitative PCR (HT-qPCR) platform designed to detect and quantify xenobiotic degradation genes (XDGs) in diverse environmental samples. A total of 9 primer sets were validated for their high specificity. The universal primers barcoding bacterial 16S rRNA gene were included as a reference gene of IS.XDG-Chip. Specific primers were designed for each target gene, followed by PCR amplification. Amplicons displaying single bands of the expected fragment size were selected and subjected to T-A cloning. For each target, ten clones were randomly selected for Sanger sequencing.
DOI: 10.57760/sciencedb.hjs.00174
title: Multi-scale Thermal-hydraulics Methodology and its Application to Marine Small Nuclear Reactor
title: 多尺度热工水力学方法及其在海洋小型核反应堆中的应用

description:  [Background] Marine-based small nuclear reactors face unique thermal-hydraulic challenges due to periodic fluid oscillations and complex maritime movements, posing difficulties in design and safety assessments. [Purpose] This study develops a multi-scale analysis method for systematically evaluating thermal-hydraulic behavior and safety of marine SMRs under dynamic marine conditions. [Methods] First, system, subchannel, and CFD codes were modified for marine-specific factors impacting system behavior, component heat transfer, and fuel bundle analysis. Then, targeted methods for system-level, component-level, and fuel bundle scales were established, with a cross-scale data transmission mechanism enabling multi-scale simulation. [Results] Analysis reveals significant thermal-hydraulic changes under marine conditions, especially periodic oscillations in thermodynamic parameters and enhanced heat transfer coefficients under oscillatory conditions. The study further demonstrates that coupling CFD with system and subchannel codes enhances cross-scale accuracy and data coherence. [Conclusions] The proposed multi-scale analysis method effectively evaluates the safety of marine nuclear power reactors and provides theoretical support for design optimization.
description:  [Background] Marine-based small nuclear reactors face unique thermal-hydraulic challenges due to periodic fluid oscillations and complex maritime movements, posing difficulties in design and safety assessments. [Purpose] This study develops a multi-scale analysis method for systematically evaluating thermal-hydraulic behavior and safety of marine SMRs under dynamic marine conditions. [Methods] First, system, subchannel, and CFD codes were modified for marine-specific factors impacting system behavior, component heat transfer, and fuel bundle analysis. Then, targeted methods for system-level, component-level, and fuel bundle scales were established, with a cross-scale data transmission mechanism enabling multi-scale simulation. [Results] Analysis reveals significant thermal-hydraulic changes under marine conditions, especially periodic oscillations in thermodynamic parameters and enhanced heat transfer coefficients under oscillatory conditions. The study further demonstrates that coupling CFD with system and subchannel codes enhances cross-scale accuracy and data coherence. [Conclusions] The proposed multi-scale analysis method effectively evaluates the safety of marine nuclear power reactors and provides theoretical support for design optimization.
DOI: 10.57760/sciencedb.16580
title: Analyzing relationships between Motivational Regulation and Engagement using Structural Modeling Equations Chilean university students
title: Analyzing relationships between Motivational Regulation and Engagement using Structural Modeling Equations Chilean university students

description: Data from study titletd "Analyzing relationships between Motivational Regulation and Engagement using Structural Modeling Equations Chilean university students"
description: Data from study titletd "Analyzing relationships between Motivational Regulation and Engagement using Structural Modeling Equations Chilean university students"