cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.6508205.v3
title: Comprehensive analysis of Long non-coding RNA expression in dorsal root ganglion reveals cell type specificity and dysregulation following nerve injury - Supplemetary Data

description: <b>Comprehensive analysis of Long non-coding RNA expression in dorsal root ganglion reveals cell type specificity and dysregulation following nerve injury - Supplemetary Data</b> <br> <br> S. Data 1: Novel LncRNAs in mouse and rat, in syntenically conserved regions between human, mouse and rat. S. Data 2: Novel LncRNAs in mouse DRG antisense of orthologous genes in mouse and rat. S. Data 3: Novel LncRNAs in rat DRG antisense of orthologous genes in mouse and rat. S. Data 4: Neuron sub-type specificity of ENSEMBL genes and novel LncRNAs. Neuron sub-type index is 1. MHN, 2. MHN (MI, IS), 3. C-LTMR, 4. MHN (IS), 5. MHN (IS), 6. MHN, 7. MHN (NS), 8. MR, 9. MHN, 10. MR. Average log2 expression holds the average expression in the neuron sub-type where the gene or LncRNAs was higher expressed. Expression SEM hold the standard error of the mean for the average expression estimator. S. Data 5: DE analysis results for IPSC-derived sensory neurons vs IPSC. Results are DESeq2 determined for the whole gene set of ENSEMBL genes and novel LncRNAs. Experimental design is ~ cell_line*condition. S. Data 6: Expression data for all antisense LncRNAs in IPSC-derived sensory neurons vs IPSC. S. Data 7: Expression data for all intergenic LncRNAs in IPSC-derived sensory neurons vs IPSC. S. Data 8: Expression data for all LncRNAs antisense of pain genes in IPSC-derived sensory neurons vs IPSC. S. Data 9: Expression data for all intergenic LncRNAs adjacent to pain genes in IPSC-derived sensory neurons vs IPSC. S. Data 10: Novel LncRNAs in human IPSC and mouse, in syntenically conserved regions between human, mouse and rat. S. Data 11: Novel LncRNAs in human IPSC antisense of orthologous genes in human and mouse. S. Data 12: DE analysis results for rat DRG SNT vs Sham. Results are DESeq2 determined for the whole gene set of ENSEMBL genes and novel LncRNAs. Experimental design is ~ condition. S. Data 13: Expression data for all antisense LncRNAs in rat DRG SNT vs Sham. S. Data 14: Expression data for all intergenic LncRNAs rat DRG SNT vs Sham. S. Data 15: DE analysis results for BALB/c mouse DRG SNI vs Sham. Results are DESeq2 determined for the whole gene set of ENSEMBL genes and novel LncRNAs. Experimental design is ~ sex + strain*condition. S. Data 16: DE analysis results for B10.D2 mouse DRG SNI vs Sham. Results are DESeq2 determined for the whole gene set of ENSEMBL genes and novel LncRNAs. Experimental design is ~ sex + strain*condition. S. Data 17: Expression data for all antisense LncRNAs in mouse DRG SNI vs Sham. S. Data 18: Expression data for all intergenic LncRNAs mouse DRG SNI vs Sham. <br>
DOI: 10.6084/m9.figshare.6508187
title: OTU and Taxonomy tables

description: OTU and taxonomy tables The provided operational taxonomic unit (OTU) table and associated taxonomy table were generated with the program Quantitative Insights Into Microbial Ecology (QIIME) as described in the methods sections of the journal article.<br> <b>Reference</b> <b>Ingham AC, Kielsen K, Cilieborg MS, Lund O, Holmes S, Aarestrup FM, Müller KG, and Pamp SJ. (2019) </b>Specific gut microbiome members are associated with distinct immune markers in pediatric allogeneic hematopoietic stem cell transplantation. Microbiome 7:131 https://doi.org/10.1186/s40168-019-0745-z <br>
DOI: 10.6084/m9.figshare.6507722
title: Non-medical Switching From Originator Tumor Necrosis Factor Inhibitors to Their Biosimilars: Systematic Review of Randomized Controlled Trials and Real-World Studies

description: <b>Article full text</b><br><br>The full text of this article can be found here<b>.</b> <br><b>Provide enhanced content for this article</b><br>If you are an author of this publication and would like to provide additional enhanced content for your article then please contact <b>adisrapidplus@springer.com</b>.<br>The journal offers a range of additional features designed to increase visibility and readership. All features will be thoroughly peer reviewed to ensure the content is of the highest scientific standard and all features are marked as ‘peer reviewed’ to ensure readers are aware that the content has been reviewed to the same level as the articles they are being presented alongside. Moreover, all sponsorship and disclosure information is included to provide complete transparency and adherence to good publication practices. This ensures that however the content is reached the reader has a full understanding of its origin. No fees are charged for hosting additional open access content.<br>Other enhanced features include, but are not limited to:<br>• Slide decks• Videos and animations• Audio abstracts • Audio slides<br>
DOI: 10.6084/m9.figshare.6507722.v2
title: Non-medical Switching From Originator Tumor Necrosis Factor Inhibitors to Their Biosimilars: Systematic Review of Randomized Controlled Trials and Real-World Studies

description: <strong>Article full text</strong><br> <br> The article associated with this content has been accepted for online publication and is in the final stages of production. The link to the full text will be made available on this page in the next few days. <br> <br> <strong>Provide enhanced digital features for this article</strong><br><br> If you are an author of this publication and would like to provide additional enhanced digital features for your article then please contact adisrapidplus@springer.com.<br> <br> The journal offers a range of additional features designed to increase visibility and readership. All features will be thoroughly peer reviewed to ensure the content is of the highest scientific standard and all features are marked as ‘peer reviewed’ to ensure readers are aware that the content has been reviewed to the same level as the articles they are being presented alongside. Moreover, all sponsorship and disclosure information is included to provide complete transparency and adherence to good publication practices. This ensures that however the content is reached the reader has a full understanding of its origin. No fees are charged for hosting additional open access content.<br> <br> Other enhanced features include, but are not limited to:<br> • Slide decks<br> • Videos and animations<br> • Audio abstracts<br> • Audio slides<br><br>
DOI: 10.6084/m9.figshare.6507722.v3
title: Non-medical Switching From Originator Tumor Necrosis Factor Inhibitors to Their Biosimilars: Systematic Review of Randomized Controlled Trials and Real-World Studies

description: <b>Please note:</b><b><br></b> The video accompanying the manuscript represents the opinions of the authors.<br> <b>Funding:</b> AbbVie funded this review, was involved in the collection, analysis, and interpretation of the data, and in the writing, review, and approval of the publication. Article processing charges were funded by AbbVie.<br> <b>Disclosures:</b> Syed Numan is a full-time employee of AbbVie and may own AbbVie stock or stock options. Freddy Faccin is a full-time employee of AbbVie and may own AbbVie stock or stock options. <b>Compliance with Ethics Guidelines: </b>This article is based on previously conducted studies and does not contain any studies with human participants or animals performed by any of the authors.<br> <b>Copyright: </b> The Authors 2018. This video is distributed under the terms of the Creative Commons Attribtuion Noncommercial Licence which permits any noncommerical use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited. <strong>Article full text</strong><br> <br> The article associated with this content has been accepted for online publication and is in the final stages of production. The link to the full text will be made available on this page in the next few days. <br> <br> <strong>Provide enhanced digital features for this article</strong><br> If you are an author of this publication and would like to provide additional enhanced digital features for your article then please contact adisrapidplus@springer.com.<br> <br> The journal offers a range of additional features designed to increase visibility and readership. All features will be thoroughly peer reviewed to ensure the content is of the highest scientific standard and all features are marked as ‘peer reviewed’ to ensure readers are aware that the content has been reviewed to the same level as the articles they are being presented alongside. Moreover, all sponsorship and disclosure information is included to provide complete transparency and adherence to good publication practices. This ensures that however the content is reached the reader has a full understanding of its origin. No fees are charged for hosting additional open access content.<br> <br> Other enhanced features include, but are not limited to:<br> • Slide decks<br> • Videos and animations<br> • Audio abstracts<br> • Audio slides<br>
DOI: 10.6084/m9.figshare.6507722.v4
title: Non-medical Switching From Originator Tumor Necrosis Factor Inhibitors to Their Biosimilars: Systematic Review of Randomized Controlled Trials and Real-World Studies

description: <b>Please note:</b>The video accompanying this manuscript represents the opinions of the authors.<br><br> <b>Funding</b>AbbVie funded this review, was involved in the collection, analysis, and interpretation of the data, and in the writing, review, and approval of the publication. Article processing charges were funded by AbbVie.<br> <b>Disclosures</b>Syed Numan is a full-time employee of AbbVie and may own AbbVie stock or stock options. Freddy Faccin is a full-time employee of AbbVie and may own AbbVie stock or stock options. <b><br></b><b>Compliance with Ethics Guidelines:</b>This article is based on previously conducted studies and does not contain any studies with human participants or animals performed by any of the authors.<br> <b>Copyright</b>The Authors 2018. This video is distributed under the terms of the Creative Commons Attribtuion Noncommercial Licence which permits any noncommerical use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited. <b><br></b><b>Article full text</b><br>The full text of this article can be found here<b>.</b> <br><b>Provide enhanced content for this article</b><br>If you are an author of this publication and would like to provide additional enhanced content for your article then please contact <b>adisrapidplus@springer.com</b>.<br>The journal offers a range of additional features designed to increase visibility and readership. All features will be thoroughly peer reviewed to ensure the content is of the highest scientific standard and all features are marked as ‘peer reviewed’ to ensure readers are aware that the content has been reviewed to the same level as the articles they are being presented alongside. Moreover, all sponsorship and disclosure information is included to provide complete transparency and adherence to good publication practices. This ensures that however the content is reached the reader has a full understanding of its origin. No fees are charged for hosting additional open access content.<br>Other enhanced features include, but are not limited to:<br>• Slide decks• Videos and animations• Audio abstracts • Audio slides<br>
DOI: 10.6084/m9.figshare.6507722.v6
title: Non-medical Switching From Originator Tumor Necrosis Factor Inhibitors to Their Biosimilars: Systematic Review of Randomized Controlled Trials and Real-World Studies

description: <b>Article full text</b><br><br>The full text of this article can be found here<b>.</b> <br><b>Provide enhanced content for this article</b><br>If you are an author of this publication and would like to provide additional enhanced content for your article then please contact <b>adisrapidplus@springer.com</b>.<br>The journal offers a range of additional features designed to increase visibility and readership. All features will be thoroughly peer reviewed to ensure the content is of the highest scientific standard and all features are marked as ‘peer reviewed’ to ensure readers are aware that the content has been reviewed to the same level as the articles they are being presented alongside. Moreover, all sponsorship and disclosure information is included to provide complete transparency and adherence to good publication practices. This ensures that however the content is reached the reader has a full understanding of its origin. No fees are charged for hosting additional open access content.<br>Other enhanced features include, but are not limited to:<br>• Slide decks• Videos and animations• Audio abstracts • Audio slides<br>
DOI: 10.6084/m9.figshare.6507722.v5
title: Non-medical Switching From Originator Tumor Necrosis Factor Inhibitors to Their Biosimilars: Systematic Review of Randomized Controlled Trials and Real-World Studies

description: <b>Please note:</b>The video accompanying this manuscript represents the opinions of the authors.<br><br> <b>Funding</b>AbbVie funded this review, was involved in the collection, analysis, and interpretation of the data, and in the writing, review, and approval of the publication. Article processing charges were funded by AbbVie.<br> <b>Disclosures</b>Syed Numan is a full-time employee of AbbVie and may own AbbVie stock or stock options. Freddy Faccin is a full-time employee of AbbVie and may own AbbVie stock or stock options. <b><br></b><b>Compliance with Ethics Guidelines:</b>This article is based on previously conducted studies and does not contain any studies with human participants or animals performed by any of the authors.<br> <b>Copyright</b>The Authors 2018. This video is distributed under the terms of the Creative Commons Attribtuion Noncommercial Licence which permits any noncommerical use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited. <b><br></b><b>Article full text</b><br>The full text of this article can be found here<b>.</b> <br><b>Provide enhanced content for this article</b><br>If you are an author of this publication and would like to provide additional enhanced content for your article then please contact <b>adisrapidplus@springer.com</b>.<br>The journal offers a range of additional features designed to increase visibility and readership. All features will be thoroughly peer reviewed to ensure the content is of the highest scientific standard and all features are marked as ‘peer reviewed’ to ensure readers are aware that the content has been reviewed to the same level as the articles they are being presented alongside. Moreover, all sponsorship and disclosure information is included to provide complete transparency and adherence to good publication practices. This ensures that however the content is reached the reader has a full understanding of its origin. No fees are charged for hosting additional open access content.<br>Other enhanced features include, but are not limited to:<br>• Slide decks• Videos and animations• Audio abstracts • Audio slides<br>
DOI: 10.6084/m9.figshare.6507437
title: A 3D geological model of a structurally complex Alpine region as a basis for interdisciplinary research

description: Dataset representing a 3D geological reconstruction of the a section of the Nappe de Morlces, Switzerland. Associated with "A 3D geological model of a structurally complex Alpine region as a basis for interdisciplinary research" (Thornton et al.)
DOI: 10.6084/m9.figshare.6507377
title: Code to analyse immunohistochemistry data

description: These codes analyse and display capillary characteristics (such as diameters, thickness) from 2D immunohistochemistry images.<br>The fig1.m,fig2.m,fig3.m,fig4.m create images which we are planning to submit for publication in the PNAS journal in an article titled 'Quantitative histomorphometry of capillary microstructure in deep white matter'.<br>There are 3 different fitting methods in these codes which which model the capillaries in the immunohistochemically-labeled histology images with an increasing level of detail, regarding inclination and boundary shape.
DOI: 10.6084/m9.figshare.6507377.v1
title: Code to analyse immunohistochemistry data

description: These codes analyse and display capillary characteristics (such as diameters, thickness) from 2D immunohistochemistry images.<br>The fig1.m,fig2.m,fig3.m,fig4.m create images which we are planning to submit for publication in the PNAS journal in an article titled 'Quantitative histomorphometry of capillary microstructure in deep white matter'.<br>There are 3 different fitting methods in these codes which which model the capillaries in the immunohistochemically-labeled histology images with an increasing level of detail, regarding inclination and boundary shape.
DOI: 10.6084/m9.figshare.6507359
title: Original and fitted capillary images of 75 subjects

description: These MATLAB data files (.mat files) from 75 subjects (25 Control, 25 lesions and 25 normal appearing white matter), each contain the individual capillary images (variable name: 'cylinders') the fitted capillary images (variable name: 'fit_cylinders') and fitted parameters (variable name: 'fit_params').
DOI: 10.6084/m9.figshare.6507347
title: Supplementary Material for: Coxsackievirus A24 Variant Associated with Acute Haemorrhagic Conjunctivitis Cases, French Guiana, 2017

description: In 2017, numerous cases of acute haemorrhagic conjunctivitis (AHC) were reported in the Caribbean and in South America. Preliminary reports identified adenoviruses and enteroviruses in some patient samples but, until now, none of the etiologic agents have been fully characterized. We report the full-length genomic sequences of 4 coxsackievirus A24 (CV-A24) isolates collected from AHC patients in French Guiana during this outbreak (May and June 2017). These isolates are very closely related and belong to the genotype IV of CV-A24 variant, which consists of strains sampled worldwide during AHC outbreaks in the 2000s and 2010s. No recombination events were detected within the genomic sequences, indicating that members of this genotype have continuously circulated worldwide for more than 10 years without undergoing recombination with other enteroviruses. This unusual trait could be due to their ocular tropism that could impede genetic exchanges between these viruses and other enteroviruses, which replicate mainly in the gut.
DOI: 10.6084/m9.figshare.6507359.v1
title: Original and fitted capillary images of 75 subjects

description: These MATLAB data files (.mat files) from 75 subjects (25 Control, 25 lesions and 25 normal appearing white matter), each contain the individual capillary images (variable name: 'cylinders') the fitted capillary images (variable name: 'fit_cylinders') and fitted parameters (variable name: 'fit_params').
DOI: 10.6084/m9.figshare.6507347.v1
title: Supplementary Material for: Coxsackievirus A24 Variant Associated with Acute Haemorrhagic Conjunctivitis Cases, French Guiana, 2017

description: In 2017, numerous cases of acute haemorrhagic conjunctivitis (AHC) were reported in the Caribbean and in South America. Preliminary reports identified adenoviruses and enteroviruses in some patient samples but, until now, none of the etiologic agents have been fully characterized. We report the full-length genomic sequences of 4 coxsackievirus A24 (CV-A24) isolates collected from AHC patients in French Guiana during this outbreak (May and June 2017). These isolates are very closely related and belong to the genotype IV of CV-A24 variant, which consists of strains sampled worldwide during AHC outbreaks in the 2000s and 2010s. No recombination events were detected within the genomic sequences, indicating that members of this genotype have continuously circulated worldwide for more than 10 years without undergoing recombination with other enteroviruses. This unusual trait could be due to their ocular tropism that could impede genetic exchanges between these viruses and other enteroviruses, which replicate mainly in the gut.
DOI: 10.6084/m9.figshare.6507128
title: Supplementary Material for: Genome-Wide Association Study of Erosive Tooth Wear in a Finnish Cohort

description: Erosive tooth wear is defined as irreversible loss of dental tissues due to intrinsic or extrinsic acids, exacerbated by mechanical forces. Recent studies have suggested a higher prevalence of erosive tooth wear in males, as well as a genetic contribution to susceptibility to erosive tooth wear. Our aim was to examine erosive tooth wear by performing a genome-wide association study (GWAS) in a sample of the Northern Finland Birth Cohort 1966 (<i>n</i> = 1,962). Erosive tooth wear was assessed clinically using the basic erosive wear examination. A GWAS was performed for the whole sample as well as separately for males and females. We identified one genome-wide significant signal (rs11681214) in the GWAS of the whole sample near the genes <i>PXDN</i> and <i>MYT1L</i>. When the sample was stratified by sex, the strongest genome-wide significant signals were observed in or near the genes <i>FGFR1, C8orf86, CDH4, SCD5, F2R</i>,<i></i> and<i> ING1</i>. Additionally, multiple suggestive association signals were detected in all GWASs performed. Many of the signals were in or near the genes putatively related to oral environment or tooth development, and some were near the regions considered to be associated with dental caries, such as 2p24, 4q21, and 13q33. Replications of these associations in other samples, as well as experimental studies to determine the biological functions of associated genetic variants, are needed.
DOI: 10.6084/m9.figshare.6507128.v1
title: Supplementary Material for: Genome-Wide Association Study of Erosive Tooth Wear in a Finnish Cohort

description: Erosive tooth wear is defined as irreversible loss of dental tissues due to intrinsic or extrinsic acids, exacerbated by mechanical forces. Recent studies have suggested a higher prevalence of erosive tooth wear in males, as well as a genetic contribution to susceptibility to erosive tooth wear. Our aim was to examine erosive tooth wear by performing a genome-wide association study (GWAS) in a sample of the Northern Finland Birth Cohort 1966 (<i>n</i> = 1,962). Erosive tooth wear was assessed clinically using the basic erosive wear examination. A GWAS was performed for the whole sample as well as separately for males and females. We identified one genome-wide significant signal (rs11681214) in the GWAS of the whole sample near the genes <i>PXDN</i> and <i>MYT1L</i>. When the sample was stratified by sex, the strongest genome-wide significant signals were observed in or near the genes <i>FGFR1, C8orf86, CDH4, SCD5, F2R</i>,<i></i> and<i> ING1</i>. Additionally, multiple suggestive association signals were detected in all GWASs performed. Many of the signals were in or near the genes putatively related to oral environment or tooth development, and some were near the regions considered to be associated with dental caries, such as 2p24, 4q21, and 13q33. Replications of these associations in other samples, as well as experimental studies to determine the biological functions of associated genetic variants, are needed.
DOI: 10.6084/m9.figshare.6507056
title: Data for figshar_ms2.xlsx

description: Data for submission to Nature Evolution and Ecology