cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5061/dryad.tx95x6b18
title: Data from: Early prediction of in-hospital mortality in patients with congestive heart failure in intensive care unit: a retrospective observational cohort study

description: Objective: Congestive heart failure (CHF) is a clinical syndrome
 in which heart disease progresses to a severe stage. Risk assessment and
 early diagnosis of death in patients with CHF are critical to patient
 prognosis and treatment. The purpose of this study was to establish a
 nomogram predicting in-hospital death for CHF patients in the ICU.
 Design: A retrospective observational cohort study. Setting and
 participants: The data of study from 30,411 CHF patients in the
 Medical Information Mart for Intensive Care (MIMIC-IV) database and the
 eICU Collaborative Research Database (eICU-CRD). Primary
 outcome: In-hospital mortality. Results: The inclusion
 criteria were met by 15983 subjects, whose in-hospital mortality
 rate was 12.4%. Multivariate analysis determined that the independent risk
 factors were age, race, norepinephrine, dopamine, phenylephrine,
 vasopressin, mechanical ventilation, intubation, HepF, heart
 rate, respiratory rate, temperature, SBP, AG, BUN,
 creatinine, chloride, MCV, RDW, and WBC. The
 C-index of the nomogram (0.767, 95%CI: 0.759–0.779) was
 superior to that of the traditional SOFA,
 APSIII and GWTGHF score, indicating its discrimination power. Calibration
 plots demonstrated that the predicted results are in good
 agreement with the observed results. The decision curves of the
 derivation and validation sets both had net benefits. Conclusion:
 The twenty independent risk factors
 for in-hospital mortality of CHF patients were
 age, race, norepinephrine, dopamine, phenylephrine, vasopressin,
 mechanical ventilation, intubation, HepF, heart rate,
 respiratory rate, temperature, SBP, AG, BUN,
 creatinine, chloride, MCV, RDW, and
 WBC. The nomogram that included these factors accurately
 predicted the in-hospital mortality of CHF patients. The novel
 nomogram has the potential to be a clinical practice
 aided predictive tool for predicting and assessing mortality in
 CHF patients in the ICU.
description: Univariate logistic regression
 analysis were used to select risk factors associated with the in-hospital
 mortality of CHF patients, and multivariate logistic regression was used
 to build the prediction model. The discrimination, calibration and
 clinical validity of the model were evaluated by AUC, calibration curve,
 Hosmer-Lemeshow χ2 test and DCA curve, respectively. Finally, data from
 15,503 CHF patients in the multi-center eICU-CRD were used for external
 validation of the established nomogram.
description: This Excel contains all the original
 data analyzed in this study.
DOI: 10.5068/d1xt3v
title: Dataset from: In-situ bidirectional human-robot value alignment

description: A prerequisite for social coordination is bidirectional communication
 between teammates, each playing two roles simultaneously: as receptive
 listeners and expressive speakers. For robots working with humans in
 complex situations with multiple goals that differ in importance, failure
 to fulfill the expectation of either role could undermine group
 performance due to misalignment of values between humans and robots.
 Specifically, a robot needs to serve as an effective listener to infer
 human users' intents from instructions and feedback, and as an
 expressive speaker to explain its decision processes to users. In this
 paper, we investigate how to foster effective bidirectional human-robot
 communications in the context of value alignment---collaborative robots
 and users form an aligned understanding of the importance of possible task
 goals. We propose an explainable artificial intelligence (XAI) system in
 which a group of robots predicts users' values by taking in-situ
 feedback into consideration, while communicating their decision processes
 to users through explanations. To learn from human feedback, our XAI
 system integrates a cooperative communication model for inferring human
 values associated with multiple desirable goals. To be interpretable to
 humans, the system simulates human mental dynamics and predicts optimal
 explanations using graphical models. We conducted psychological
 experiments to examine the core components of the proposed computational
 framework. Our results show that real-time human-robot mutual
 understanding in complex cooperative tasks is achievable with a learning
 model based on bidirectional communication. We believe this interaction
 framework can shed light on bidirectional value alignment in communicative
 XAI systems, and more broadly, in future human-machine teaming systems.
DOI: 10.5061/dryad.nvx0k6dvt
title: Effects of developmental and adult environments on ageing

description: Developmental and adult environments can interact in complex ways to
 influence the fitness of individuals. Most studies investigating effects
 of the environment on fitness focus on environments experienced and traits
 expressed at a single point in an organism’s life. However, environments
 vary with time, so the effects of the environments that organisms
 experience at different ages may interact to affect how traits change
 throughout life. Here we test whether thermal stress experienced during
 development leads individuals to cope better with thermal stress as
 adults. We manipulated temperature during both development and adulthood
 and measured a range of life-history traits, including senescence, in male
 and female seed beetles (Callosobruchus maculatus). We found that thermal
 stress during development reduced adult reproductive performance of
 females. In contrast, lifespan and age-dependent mortality were affected
 more by adult than developmental environments, with high adult
 temperatures decreasing longevity and increasing age-dependent mortality.
 Aside from an interaction between developmental and adult environments to
 affect age-dependent changes in male weight, we did not find any evidence
 of a beneficial acclimation response to developmental thermal stress.
 Overall, our results show that effects of developmental and adult
 environments can be both sex- and trait- specific, and that a full
 understanding of how environments interact to affect fitness and ageing
 requires the integrated study of conditions experienced during different
 stages of ontogeny.
description: This dataset was collected using an experiment on seed beetles
 which tests for effects of developmental and adult environments on ageing.
 It has been processed by splitting the overall dataset into 3 datasheets:
 one one non age-dependent traits, the other on age-dependent fecundity in
 females, and third on age-dependent weight change in males.
description: Excel or R
DOI: 10.5061/dryad.kprr4xh74
title: DNA metabarcoding reveals impact of local recruitment, dispersal, and hydroperiod on assembly of a zooplankton metacommunity

description: Understanding the environmental impact on the assembly of local
 communities in relation to their spatial and temporal connectivity is
 still a challenge in metacommunity ecology. This study aims to unravel
 underlying metacommunity processes and environmental factors that result
 in observed zooplankton communities. Unlike most metacommunity studies, we
 jointly examine active and dormant zooplankton communities using a DNA
 metabarcoding approach to overcome limitations of morphological species
 identification. We applied two-fragment (COI and
 18S) metabarcoding to monitor communities of 24 kettle holes over
 a two-year period to unravel (I) spatial and temporal connectivity of the
 communities, (II) environmental factors influencing local communities, and
 (III) dominant underlying metacommunity processes in this system. We found
 a strong separation of zooplankton communities from kettle holes of
 different hydroperiods (degree of permanency) throughout the season, while
 the community composition within single kettle holes did not differ
 between years. Species richness was primarily dependent on pH and
 permanency, while species diversity (Shannon Index) was influenced by
 kettle hole location. Community composition was impacted by kettle hole
 size and surrounding field crops. Environmental processes dominated
 temporal and spatial processes. Sediment communities showed a different
 composition compared to water samples but did not differ between ephemeral
 and permanent kettle holes. Our results suggest that communities are
 mainly structured by environmental filtering based on pH, kettle hole
 size, surrounding field crops, and permanency. Environmental filtering
 based on specific conditions in individual kettle holes seems to be the
 dominant process in community assembly in the studied zooplankton
 metacommunity.
DOI: 10.5061/dryad.6hdr7sr3v
title: Data from: Mechanical fatigue in microtubules

description: Mechanical failure of biological nanostructures due to sustained force
 application has been studied in great detail. In contrast, fatigue failure
 arising from repeated application of subcritical stresses has received
 little attention despite its prominent role in engineering and potentially
 biology. Here, taxol-stabilized microtubules are up to 256 times bent into
 sinusoidal shapes of varying wavelength and the frequency of breaking
 events are observed. These experiments allow the calculation of fatigue
 life parameters for microtubules. Repeated buckling due to 12.5%
 compression – equal to the compression level experienced by microtubules
 in contracting cardiomyocytes – results in failure after in average 5
 million cycles, whereas at 20% compression failure occurs after in average
 one thousand cycles. The fatigue strength (Basquin) exponent B is
 estimated as -0.06.
description: # Mechanical fatigue in microtubules
 [https://doi.org/10.5061/dryad.6hdr7sr3v](https://doi.org/10.5061/dryad.6hdr7sr3v) ## Description of the data and file structure **Supplementary Videos 1\-5 \| 12\.5% Compression Assays\.** Videos of the compression assays of fluorescently labeled microtubules undergoing 12.5% compression on flexible PDMS surface coated with kinesin-1. Each video contains 13 frames, two for each measured compression cycle (1, 4, 16, 32, 64, and 256), alternating between the compressed and subsequent relaxed stage of the cycle. The final frame of each video is a stretch of 2.5% after 256 compression cycles that is used to identify breaking events. Field of View: 277.33 μm x 234.00 μm. **Supplementary Videos 6\-15 \| 20% Compression Assays\.** Videos of the compression assays of fluorescently labeled microtubules undergoing 20% compression on flexible PDMS surface coated with kinesin-1. Each video contains 9 frames, two for each measured compression cycle (1, 2, 4, and 8), alternating between the compressed and subsequent relaxed stage of the cycle. The final frame of each video is a stretch of 2.5% after 8 compression cycles that is used to identify breaking events. Field of View: 277.33 μm x 234.00 μm.
DOI: 10.15468/dl.3675dr
title: Occurrence Download

description: A dataset containing 4973 species occurrences available in GBIF matching the query:
{
 "and" : [
 "DatasetKey is Ohio State University Tetrapod Division - Amphibian Collection (OSUM)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present"
 ]
}

 The dataset includes 4973 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0003164-260126135527185/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5061/dryad.s1rn8pkbn
title: Data from: Species recognition limits mating between hybridizing ant species

description: Identifying mechanisms limiting hybridization is a central goal of
 speciation research. Here, we studied pre-mating and post-mating barriers
 to hybridization between two ant species, Formica selysi and Formica
 cinerea. These species hybridize in the Rhône valley in Switzerland, where
 they form a mosaic hybrid zone, with limited introgression from F. selysi
 into F. cinerea. There was no sign of temporal isolation between the two
 species in the production of queens and males. With choice experiments, we
 showed that queens and males strongly prefer to mate with conspecifics.
 Yet we did not detect post-mating barriers caused by genetic
 incompatibilities. Specifically, hybrids of all sexes and castes were
 found in the field and F1 hybrid workers did not show reduced viability
 compared to non-hybrid workers. To gain insights into the cues involved in
 species recognition, we analyzed the cuticular hydrocarbons of queens,
 males and workers and staged dyadic encounters between workers. Cuticular
 hydrocarbon profiles differed markedly between species, but were similar
 in F. cinerea and hybrids. Accordingly, workers also discriminated
 species, but they did not discriminate F. cinerea and hybrids. We discuss
 how the CHC-based recognition system of ants may facilitate the
 establishment of pre-mating barriers to hybridization, independent of
 hybridization costs.
DOI: 10.35097/cffncun0dddhf98m
title: Development of a soda-lime glass feedstock for injection molding

description: Die Forschungsdaten beschreiben die Entwicklung von Natron-Kalk-Glas haltigen Formmassen für den Pulverspritzguss.
description: The research data describes the development of soda-lime-glass-containing feedstocks for powder injection molding.
description: Die Rohdaten sind die Grundlage für eine zukünftige Publikation.
DOI: 10.5061/dryad.nvx0k6dvv
title: European badger (Meles meles) responses to low-intensity, selective culling: using mark recapture and relatedness data to assess social perturbation

description: Culling the main wildlife host of bovine tuberculosis in Great Britain
 (GB) and Ireland, the European badger (Meles meles) to reduce infections
 in cattle, has been employed in both territories. In GB, this has been
 controversial, with results suggesting that culling induces disturbance to
 badger social structure, facilitating wider disease dissemination.
 Previous analyses hypothesized that even very low-level, selective culling
 may cause similar deleterious effects by increasing ranging of individuals
 and greater mixing between social-groups. To assess this hypothesis, a
 novel, prospective, landscape-scale ‘before-and-after’ Test and vaccinate
 or remove (TVR) study was implemented. Test-positive badgers were culled
 and test-negative badgers were BCG vaccinated and released. Mark-recapture
 metrics of badger ranging and genetic metrics of social group relatedness
 did not change significantly over the study period. However, selective
 culling was associated with a localised reduction in social-group
 relatedness in culled groups. Synthesis and application: Ecological
 context is important; extrapolation across territories and other disease
 epidemiological-systems (epi-systems) is likely to be challenging.
 However, we demonstrate that small-scale, selective removal of
 test-positive badgers was not associated with metrics of increased ranging
 but was associated with localised changes in social-group relatedness.
 This adds to the evidence base on badger control options for policy
 makers.
DOI: 10.5061/dryad.vt4b8gtvm
title: Metabarcoding for biodiversity inventory blind spots: A test case using the beetle fauna of an insular cloud forest

description: Soils harbour a rich arthropod fauna, but many species are still not
 formally described (Linnaean shortfall), and the distribution of those
 already described is poorly understood (Wallacean shortfall).
 Metabarcoding holds much promise to fill this gap, however, nuclear copies
 of mitochondrial genes, and other artefacts lead to taxonomic inflation,
 which compromises the reliability of biodiversity inventories. Here we
 explore the potential of a bioinformatic approach to jointly “denoise” and
 filter non-authentic mitochondrial sequences from metabarcode reads to
 obtain reliable soil beetle inventories and address open questions in soil
 biodiversity research, such as the scale of dispersal constraints in
 different soil layers. We sampled cloud forest arthropod communities from
 49 sites in the Anaga peninsula of Tenerife (Canary Islands). We performed
 whole organism community DNA (wocDNA) metabarcoding, and built a local
 reference database with COI barcode sequences of 310 species of Coleoptera
 for filtering reads and the identification of metabarcoded species. This
 resulted in reliable haplotype data after considerably reducing nuclear
 mitochondrial copies and other artefacts. Comparing our results with
 previous beetle inventories, we found: (i) new species records,
 potentially representing undescribed species; (ii) new distribution
 records, and; (iii) validated phylogeographic structure when compared with
 traditional sequencing approaches. Analyses also revealed evidence for
 higher dispersal constraint within deeper soil beetle communities,
 compared to those closer to the surface. The combined power of barcoding
 and metabarcoding contribute to mitigate the important shortfalls
 associated with soil arthropod diversity data, and thus address unresolved
 questions for this vast biodiversity fraction.
description: <strong>Extended local reference database:
 </strong>mtDNA COI barcode sequences used as a reference to identify
 metabarcoding reads and to filter putative non-authentic mitochondrial
 reads by using metaMATE. These sequences have been obtained from two
 sources: (1) Sanger sequencing of the COI barcode region of beetles
 collected in different places across the island of Tenerife; and (2)
 sequences from the NCBI nt database that matched metabarcoding
 reads. <strong>Metabarcoding raw data:
 </strong>metabarcoding raw sequences of the COI barcode region of 98
 libraries obtained by sampling the beetle soil community in the Anaga
 laurel forest of the island of Tenerife.
 <strong>Metabarcoding community table:
 </strong>community table with the distribution of metabarcoding ASVs (amplicon sequence variants) on each library after denoising and metaMATE filtering.
DOI: 10.5061/dryad.d2547d851
title: Data for: Single-cell multi-omics in the medicinal plant Catharanthus roseus

description: Advances in omics technologies now permit the generation of highly
 contiguous genome assemblies, detection of transcripts and metabolites at
 the level of single cells and high-resolution determination of gene
 regulatory features. Here, using a complementary, multi-omics approach, we
 interrogated the monoterpene indole alkaloid (MIA) biosynthetic pathway
 in Catharanthus roseus, a source of leading anticancer drugs. We
 identified clusters of genes involved in MIA biosynthesis on the
 eight C. roseus chromosomes and extensive gene
 duplication of MIA pathway genes. Clustering was not limited to the linear
 genome, and through chromatin interaction data, MIA pathway genes were
 present within the same topologically associated domain, permitting the
 identification of a secologanin transporter. Single-cell RNA-sequencing
 revealed sequential cell-type-specific partitioning of the leaf MIA
 biosynthetic pathway that, when coupled with a single-cell metabolomics
 approach, permitted the identification of a reductase that yields the
 bis-indole alkaloid anhydrovinblastine. We also revealed
 cell-type-specific expression in the root MIA pathway.
DOI: 10.5061/dryad.0zpc86714
title: Fitness of gnotobiotic Rhodnius prolixus nymphs

description: Kissing bugs (Hempitera: Reduviidae) are obligately and exclusively blood
 feeding insects. Vertebrate blood is thought to provide insufficient B
 vitamins to insects, which rely on obligate symbiotic relationships with
 bacteria that provision these nutrients. Kissing bugs harbor
 environmentally acquired bacteria in their gut lumen, without which they
 are unable to develop to adulthood. Early experiments identified a single
 bacterial species, Rhodococcus rhodnii, as a symbiont of Rhodnius
 prolixus, but modern studies of the kissing bug microbiome suggest that R.
 rhodnii is not always present or abundant in wild-caught individuals. We
 asked whether R. rhodnii or other bacteria alone could function as
 symbionts of R. prolixus. Bacteria-free (axenic) insects were produced
 whose microbiome could be experimentally manipulated to produce insects
 with known microbiomes (gnotobiotic). We found that gnotobiotic insects
 harboring R. rhodnii alone developed faster, had higher survival, and laid
 more eggs than gnotobiotic R. prolixus harboring other bacterial
 monocultures, including other described symbionts of kissing bugs and
 several related Rhodococcus species. R. rhodnii grew to high titer in the
 guts of R. prolixus while other tested species were found at much lower
 abundance. Rhodococcus species tested had nearly identical B vitamin
 biosynthesis genes, and dietary supplementation of B vitamins had a
 relatively minor effect on development and survival of gnotobiotic R.
 prolixus. Our results indicate that R. prolixus have a higher fitness when
 harboring R. rhodnii than other bacteria tested, and that symbiont B
 vitamin synthesis is likely a necessary but not sufficient function of gut
 bacteria in kissing bugs.
description: Data were collected by observation of nymphs, counting deposition
 of eggs, and qPCR of bacterial DNA extracted from insects. 
description: All data should be viewable in a text editor. Data were analyzed
 with R.
DOI: 10.5061/dryad.2280gb5vq
title: Reproductive compensation and selection among viable embryos drive the evolution of polyembryony

description: Simple polyembryony -- where one gametophyte produces multiple embryos
 with different sires but the same maternal haplotype -- is common among
 vascular plants. We develop an infinite-site, forward population genetics
 model showing that together polyembryony’s two benefits --
 "reproductive compensation" achieved by providing a backup for
 inviable embryos, and the opportunity to favor the fitter of surviving
 embryos, can favor its evolution. Our model tests how these factors can
 favor the evolution of polyembryony, and how these underlying benefits of
 polyembryony shape the genetic load under a range of biological
 parameters. While these two benefits are difficult to disentangle in
 nature, we construct variant models of polyembryony that either only
 include or only exclude the opportunity for reproductive compensation. We
 find that reproductive compensation strongly favors the evolution of
 polyembryony, and that polyembryony is favored much more weekly in its
 absence, suggesting that the benefit of a backup embryo is a major force
 favoring polyembryony. Remarkably we find nearly identical results in
 cases in which mutations impact either embryo or post-embryonic fitness
 (no pleiotropy), and in cases in which mutations have identical fitness
 effects embryo or post-embryonic fitness (extreme pleiotropy). Finally, we
 find that the consequences of polyembryony depends on its function –
 polyembryony results in a decrease in mean embryonic fitness when acting
 as a mechanism of embryo compensation, and ultimately increases mean
 embryonic fitness when we exclude this potential benefit.
description: The "dataset" was generated by computer simulation in R
 (code included).
description: Our data includes code written in the R programming language and
 requires that R and the tidyverse package are installed.
DOI: 10.5518/1495
title: In-situ TOF-SIMS, SEM, and XRD data for Borate Coating on Steel

description: This dataset contains extracted time-of-flight secondary mass spectroscopy (TOF-SIMS) acquired at a series of temperature on borate coating on steel samples. The dataset also contains associated complementary data. such as X-ray difrraction at different temperatures, scanning electron diffraction images at different temperatures, and TOF-SIMS control experiments at individual temperatures and a different beam energy. The data is extracted and presented in HDF5 file format, consistent with the hyperspy Python package, an open-source package coded in Python.