cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17632/xfbrfhtt6p
title: CX-5461 potentiates imatinib-induced apoptosis in K562 cells by stimulating KIF1B expression (Part 3)

description: The selective RNA polymerase I inhibitor CX-5461 has been shown to be effective in treating some types of leukemic disorders. Emerging evidence suggests that combined treatments with CX-5461 and other chemotherapeutic agents may achieve enhanced effectiveness as compared to monotherapies. In the present study, we tested whether CX-5461 could potentiate the effect of imatinib in the human chronic myeloid leukemia cell line K562. Cells were divided into 3 treatment groups (with 3 independent biological replications in each group): control, imatinib (100 nM for 48 hr) alone, and imatinib+CX-5461 (100 nM for 48 hr). Genome-wide mRNA sequencing was performed.
DOI: 10.6084/m9.figshare.20483655.v1
title: Minor (U12-type) intron metadata for thousands of eukaryotic genomes

description: Information about minor introns and their containing genes for thousands of eukaryotic genomes. <br> The columns in the file are: Species: full species name Abbreviation: species name abbreviation Kingdom/phylum: taxonomic info as assigned by NCBI Accession: associated accession ID (dependent on source) Assembly: assembly ID Tax. ID: taxonomic ID (NCBI) Minor intron density (%): percentage of annotated introns which are minor (U12) type Total minor introns: number of annotated minor introns Total introns: total number of annotated introns Corrected minor introns: introns with non-canonical boundaries in the original annotations which contain strong minor-like motifs nearby, "corrected" to the new boundaries; may be enriched for false positives depending on annotation quality BUSCO (%): complete BUSCO score Confident call: "u12-" = confidently lacking minor introns, "u12+" confidently containing minor introns; integrates information about BUSCO score and the presence/absence of minor snRNAs Minor snRNAs: names of any minor snRNAs found in the genome Intron position MWU p-value: the p-value of a two-sided Mann-Whitney U test between major and minor intron positions within their containing genes Median minor intron position: the median position of minor introns within their containing genes Median major intron position: as above, for major introns Median MIG length: the median length (bp) of minor intron-containing genes (sum of the coding sequences) Median non-MIG length: as above, for genes without minor introns Median minor intron length (bp) Median major intron length (bp) Intron length MWU p-value: the p-value of a two-sided Mann-Whitney U test between the lengths of major and minor introns Genome retrieval date Annotation retrieval date<br>
DOI: 10.17632/vt2n4kwb25
title: Morbidity melanoma data

description: This is a retrospective multicenter study on postoperative morbidity after surgical treatment for non-metastatic skin melanoma. Data were extracted from the Central National Melanoma Registry (CNMR), which is a prospectively maintained national database for melanoma treatment promoted by the IMI in 43 melanoma centers in Italy. The study was conducted according to Helsinki Declaration principles and was approved by the Ethics Committee of the Central National Melanoma Registry (CNMR). All patients gave their consent to have their data collected for scientific purpose.
DOI: 10.17632/v7gyc4fvrc
title: libras_bilingual_dataset

description: The libras_bilingual_dataset contains 68,029 aligned sentence pairs in Brazilian Portuguese and Libras gloss, a linear, written representation of Brazilian Sign Language. Provided in UTF-8 encoded Comma-Separated Values (CSV) format, it includes two columns:

portuguese: sentences in Brazilian Portuguese

libras: corresponding translations in Libras gloss format

This dataset supports research in machine translation, sign language technologies, and accessible communication systems.
DOI: 10.6084/m9.figshare.24996317.v1
title: Source Data file.zip

description: In this study, we introduced Uni-MOF, a novel framework for three-dimensional MOF representation learning on a large scale. Our goal is to achieve universal multi-gas adsorption prediction, making Uni-MOF the first comprehensive "gas adsorption estimator" for MOF materials.
DOI: 10.6084/m9.figshare.26237069.v1
title: Supplement data for letter titled "Earlier vasoconstriction in females than males with matched body size and composition in neutral-cool conditions"

description: The data are used for creating Figure 1 for the letter titled "Earlier vasoconstriction in females than males with matched body size and composition in neutral-cool conditions".
DOI: 10.6084/m9.figshare.28575158.v1
title: Results for SAP-SAM in "Detecting Undesired Process Behavior by Means of Retrieval Augmented Generation"

description: This data collection contains all results for the SAP-SAM dataset for the used approach and baselines. Due to capacity limits of GitHub, they are published separately.
DOI: 10.17632/23676xpsxf
title: AHP-BenchmarkConsistency

description: These are simulated data for Pairwise Comparison Matrices in the AHP. There are 4 pairs of data, with each pair comprising a 72000 row dataframe named df9* and a list, named sl9* of identical length. The pair corresponds to simulated AHP data, for PCMs of order 3, 4, 5, ..., 10, 11, 12. 7200 PCMs are simulated for each of the 10 orders.

* df/sl9T    these are random PCMs generated using comparison ratios from the Fundamental Scale

* df/sl9S    these are random PCMs with improved consistency by 3 applications of Harker's method; "Derivatives of the Perron root of a positive reciprocal matrix: With applications to the analytic hierarchy process", 1987, Applied Mathematics and Computing, Vol 22(11)

* df/sl9L2   these are intentional PCMs, simulated following Bose 2022, "Consistency re-evaluation in analytic hierarchy process based on simulated consistent matrices", Journal of Multi-criteria Decision Analysis, Vol 29
These are non-random PCMs, simulated in a manner akin to a rational decision maker.

* df/sl9L2test  these are intentional PCMs similar to df/sl9L2, but generated to test the method and thresholds defined
DOI: 10.6084/m9.figshare.8321285.v1
title: GHTorrent Project Commits Dataset

description: This data is a pull from GHTorrent, converted to a feather format. This data was used in https://github.com/UBC-MDS/RStudio-GitHub-Analysis.
DOI: 10.17632/599rgxhy6m
title: Dataset on isometric contractions of the elbow joint in children with and without spastic Cerebral Palsy: HD-EMG and torque

description: High-density electromyographic and torque data were collected during maximal and sub-maximal isometric contractions (force ramp) of the elbow joint with contraction levels ranging between 15-70% of the maximum voluntary contraction. Participants were children aged 5-15 years with and without spastic Cerebral Palsy. CP group: Children with spastic Cerebral Palsy. TD group: Typically developed children.
DOI: 10.17632/6k29cdfpsx
title: Effective low-cost preservation of human stools in field-based studies for helminth and microbiota analysis - Supplementary Files

description: Molecular studies of gastrointestinal infections or microbiotas require either rapid sample processing or effective interim preservation. This is difficult in remote settings in low-income countries, where the majority of the global infectious disease burden exists. Processing or freezing of samples immediately upon collection is often not feasible and the cost of commercial preservatives is prohibitive. We compared fresh freezing (the ‘gold standard’ method), with low-cost chemical preservation in (i) a salt-based buffer consisting of DMSO, EDTA and NaCl (DESS) or (ii) 2.5% potassium dichromate (PD), for soil-transmitted helminth detection and microbiota characterisation in pre-school and school-aged children from north-western Thailand. Fresh frozen samples were frozen at -20oC on collection and maintained at -80oC within ~3 days of collection until molecular analysis, with international shipping on dry ice. In contrast, chemically preserved samples were collected and stored at ~4 oC, transported on wet ice and only stored at -20oC on arrival in Australia ~8 weeks after collection, with international shipping on wet ice. DESS and PD provided better sensitivity for STH diagnosis, estimating higher infection rates (&gt;80% for Ascaris lumbricoides and &gt;60% for Trichuris trichiura; versus 56% and 15% for these parasites in fresh frozen samples) and egg abundance (inferred as gene copy number estimates). All methods performed similarly for microbiota preservation, showing no significant differences in alpha-diversity based on overall richness or inverted Simpson’s Index. All three methods performed similarly for RNA and protein preservation in a small subset of samples. Overall, DESS provided the best performance, with the added benefit of being non-toxic, compared with PD, hence making it particularly applicable for studies in remote and resource-poor settings.
DOI: 10.17632/tdyvg3n3mz
title: Магистерская диссертация 《Прогнозный анализ и оценка экономической деятельности компании на основе ее финансовой отчетности》Шан Юйжу

description: Дополнительные файлы к магистерской диссертации. Процесс расчета данных в приложении.
DOI: 10.6084/m9.figshare.19982036.v1
title: Supplementary Material for: miR-146a-5p Attenuates Allergic Airway Inflammation by Inhibiting the NLRP3 Inflammasome Activation in Macrophages

description: <b><i>Objective:</i></b> Asthma is a common inflammatory respiratory disease with increasing incidence worldwide. This study aimed to investigate the mechanism of miR-146a-5p in reducing allergic airway inflammation by inhibiting NLRP3 inflammasome activation in macrophages. <b><i>Methods:</i></b> Allergic mouse models were established by ovalbumin stimulation, and mice were treated with miR-146a-5p agomir and oe-TIRAP 3 h before OVA stimulation. The pathological changes of lung tissues were observed by hematoxylin-eosin staining. The airway hyperresponsiveness of mice were examined. The miR-146a-5p level was detected by RT-qPCR. The inflammatory cytokines (IL-18/TNF-α) and anti-inflammatory cytokine IL-10 levels in bronchoalveolar lavage fluid and serum IgE levels were examined by ELISA. Airway inflammation in mice was detected after miR-146a-5p overexpression. The levels of NLRP3/ASC/caspase1 proteins and macrophage M1/M2 surface markers in mouse lung tissues were examined using immunohistochemistry, Western blot, and flow cytometry. The targeting relationship between miR-146a-5p and TIRAP was verified by dual-luciferase assay. The p65 levels in the cytoplasm/nucleus of mouse lung tissue were measured. <b><i>Results:</i></b> miR-146a-5p was downregulated in the lung tissues of allergic mice, and miR-146a-5p overexpression alleviated airway inflammation in asthmatic mice. miR-146a-5p suppressed NLRP3 inflammasome activation in macrophages of allergic mice, reduced NLRP3/ASC/caspase1 protein levels in lung tissues, blocked M1 polarization, and promoted M2 polarization. miR-146a-5p targeted TIRAP. TIRAP overexpression partially reversed the promoting effect of miR-146a-5p on M2 polarization. miR-146a-5p can inhibit the activation of the TIRAP/NF-κB pathway. <b><i>Conclusion:</i></b> miR-146a-5p inhibited NLRP3 inflammasome activation in macrophages in the lung tissue of allergic mice, prevented pro-inflammatory phenotype M1 polarization, and promoted anti-inflammatory phenotype M2 polarization by targeting the TIRAP/NF-κB pathway, thus alleviating airway inflammation in allergic asthma.
DOI: 10.6084/m9.figshare.21948224.v1
title: Almécija et al. 2015 – Hand Proportions Data.xlsx

description: It also includes digital lengths and body mass at the individual level.
DOI: 10.6084/m9.figshare.25752078.v1
title: Molecular data of Miliuseae

description: This study aimed to comprehensively investigate the genetic relationships within the Miliuseae tribe by collecting and analyzing data from commonly used gene regions, namely <i>trnL</i>, <i>matK</i>, and <i>rbcL</i>. The primary objective was to elucidate the relationships among genera/clades and identify monophyletic and polyphyletic groups within this tribe. Additionally, the study sought to assess how the molecular complexity of Miliuseae data influences genetic analysis.
DOI: 10.6084/m9.figshare.27165414.v5
title: Dataset for Frictional behavior of the southern San Andreas fault reveals ability to host shallow slow slip events

description: Matlab data reduction file (Shreedharan), raw data files, and reduced data files for experiments. readme.txt describes input values for reduction file and output columns of .mat files.XRD_GRL25 analysis performed by ISGS XRD/XRF Materials Characterization Lab (Martin P. Pentrak)
DOI: 10.6084/m9.figshare.28927142.v1
title: A New Cosmological Model: Cyclical Time, Infinite Energy, and the Role of Black Holes as Temporal Bridges

description: This work presents a novel cosmological framework where time is conceptualized as a closed, cyclic dimension, and energy is infinitely conserved across these cycles. It reinterprets black holes as transitional bridges that redistribute energy across different time cycles. The model challenges traditional cosmological theories, offering new perspectives on entropy, dark energy, and the evolution of the universe. Observational predictions such as gravitational wave echoes and CMB anomalies are explored as potential tests for this framework
DOI: 10.6084/m9.figshare.10678097.v1
title: Processed bystander editing data

description: Python3 pickled dictionaries. Keys are target site names, values are pandas dataframes where each row is a unique editing outcome, and there is a column for each substrate nucleotide and a frequency column.
DOI: 10.6084/m9.figshare.1293647.v1
title: #Ferguson1.5-1.8.xlsx

description: Twitter data on #Ferguson. See Project Descritpion for details.
DOI: 10.6084/m9.figshare.28039316.v2
title: <b>Roles of a Y-linked iDmrt1 paralogue and Insulin-Like Androgenic Gland Hormone in Sexual Development in the Tropical Rock Lobster, </b><b><i>Panulirus ornatus</i></b>

description: This study investigates the functions of the Y-linked <i>iDmrt1</i> paralogue, <i>Po-iDMY</i> and insulin-like androgenic gland hormone (<i>Po-IAG</i>) in the process of sexual development in the tropical rock lobster, <i>Panulirus ornatus</i> (TRL). Previously, we identified that <i>Po-iDMY</i>, a male-specific heterogametic (Y-linked) paralogue of the autosomal <i>Po-iDmrt1 </i>found in TRL, is a second sex-linked <i>iDmrt</i> gene identified in invertebrates. Using 5’ and 3’ rapid amplification of cDNA ends and data from a draft male genome (with an assembly genome size of approximately 2.446 Gbp and 87% BUSCO completeness), we obtained the full-length <i>Po-iDMY</i> gene (coding for a 312 amino acids protein), which includes a 411 bp male-specific sequence located at the 3’ untranslated region of <i>Po-iDMY</i> mRNA used as a sex marker. Notably, this sex marker sequence is reported for the first time in our genome analysis. However, <i>Po-iDMY</i> is not expressed across various tissues and developmental stages across embryos, juveniles and adults. This observation suggests that Po-iDMY may not tightly regulate Po-IAG in this species, indicating that silencing <i>Po-IAG</i> could potentially induce sex change. Further expression analyses confirmed that <i>Po-IAG</i> expression is not male-specific. Despite this, <i>Po-IAG</i> silencing at an early juvenile stage generated two potential neo-females, implying that sexual manipulation could be a promising technique in TRL.
DOI: 10.6084/m9.figshare.29144420.v1
title: <b>Chemistry of Warfare (Chemical weapons in warfare: An in-depth analysis of classifications and profound effects on human physiology)</b>

description: This presentation provides a comprehensive overview of Chemical Warfare Agents (CWAs), focusing on their classification, chemical properties, and historical use. It covers the major categories of CWAs nerve agents, blister agents, choking agents, and blood agents highlighting notorious examples such as sarin, mustard gas, and phosgene. The presentation explains how these agents differ in their physical and chemical nature, modes of exposure, and the devastating effects they can have on human health and the environment. It also revisits significant historical events where these agents were deployed, offering context to their role in shaping warfare strategies across the 20th and 21st centuries.
What sets this presentation apart is its ability to blend scientific clarity with historical depth in a visually engaging format. Viewers will discover how each class of chemical agent presents unique dangers from skin-blistering vesicants to suffocating pulmonary toxins and how their development often paralleled advances in chemistry itself. With concise, well-structured slides and real-world examples, the content appeals to both scientific and general audiences, fostering awareness of the critical need for ethical responsibility in chemical research. Whether you're a student, educator, or simply curious about the darker applications of chemistry, this presentation promises an eye-opening exploration of one of the most feared categories of modern weaponry.
DOI: 10.6084/m9.figshare.4985561.v1
title: LeafMorphospace

description: This data and code accompany the manuscript "A persistent homology leaf morphospace predicts plant family and region". 182,707 leaf outlines from 141 plant families from 75 sites throughout the world were analyzed using persistent homology, a topological method. Plant family and location can be predicted at a rate higher than chance using this method and persistent homology outperforms traditional shape descriptors in prediction. Figures, tables, and legends for the manuscript are provided ("Figures _and_tables") as well as the data and code used to generate them ("Analysis"). A GitHub repository with code to calculate persistent homology accompanies this manuscript as well (https://github.com/maoli0923/Persistent-Homology-All-Leaf).
DOI: 10.17632/djncnp4548
title: Consumption Smoothing or Consumption Binging? The Effects of Government-led Consumer Credit Expansion in Brazil

description: Please see Readme_Replication_JFE_GMPS.pdf
DOI: 10.6084/m9.figshare.12936611.v1
title: eQTL database Liang et al, Genom Res, 2003

description: MCRA data for eQTL and computational analysis
DOI: 10.6084/m9.figshare.28889888.v1
title: Shift of wintertime NO<sub>3</sub><sup>-</sup> formation from O<sub>3</sub>-dominated to ·OH-dominated during Beijing’s air quality improvement (2014-2022)

description: Shift of wintertime NO<sub>3</sub><sup>-</sup> formation from O<sub>3</sub>-dominated to ·OH-dominated during Beijing’s air quality improvement (2014-2022)
DOI: 10.17632/89j7snbm2r
title: Arabidopsis_Ribo_seq_ORFeome

description: This dataset includes files from a Ribosome profiling study for ORF discovery in Arabidopsis. The associated code files: https://github.com/hsinyenwu/ORFeome abundance.txt is the Kallisto quantification with the max 2 isoforms
DOI: 10.6084/m9.figshare.12986096.v1
title: Optimization of Fermentation Conditions for Production of L-Arabinose Isomerase of Lactobacillus plantarum WU14-Raw data

description: Raw data
DOI: 10.6084/m9.figshare.17425466.v1
title: List of Australian Journals

description: A list of Australian journals that are currently (in 2021) active. Australian journals are defined here as journals that belong to or are affiliated with an Australian entity including educational institutions, non-profit organisations, small commercial publishers, government bodies and so on. The list was compiled by searching in multiple databases including Ulrich's directory of periodicals, Scopus, Web of Science, and DOAJ. Each journal was checked for information to verify whether it was Australian. The data include Title, ISSN, Country of publisher, website link, start year, Corporate author (the body that sponsors editorial processes and might own the journal or the journal might be affiliated with), publisher, Field of Research code (based on The Australian and New Zealand Standard Research Classification 2018), whether the journal is listed in Scopus, Web of Science, Excellence in Research for Australia (ERA) list of 2018.<br>
DOI: 10.6084/m9.figshare.20227503.v1
title: Data: Mapping the connectivity–conflict interface to inform conservation

description: Data used in the manuscript: Mapping the connectivity–conflict interface to inform conservation. <br> The Data Files include 3 files: 1. Locations of elephant detection/nondetection and elephant conflict, used to generate resistance and conditional conflict probabilities. 2. & 3. Data on conflict occurences used to validate the model, obtained from (2) an independently conducted questionnaire survey and (3) media reports. <br> Shapefiles and Rasters include: the study landscape extent; PAs with elephant densities; land-uses (agroforest, built up areas, crop, forest, plantations and water); and human population density from the WorldPop database. <br> The script includes code for inputting and preparing data files; generating resistance and absorption (conflict) layers; running the SAMC model; and validated model output. <br>
DOI: 10.6084/m9.figshare.22701418.v1
title: The design and development of woven textile solar panels - Supporting data - Large panel.xlsx

description: <br> Contains data relating to the characterisation of a large area textile solar panel.
DOI: 10.6084/m9.figshare.27078655.v2
title: <b>Characterization of Gut Microbiome and Cognition in Adolescents with and without Subthreshold Depression: A Shotgun Metagenomics Sequencing Study</b>

description: To investigate the association between gut microbiome and cognitive function in adolescents with subthreshold Depression (SD). Thirty-eight adolescents with SD and 139 clinically-well (CW) adolescents were recruited. Gut microbiome and cognitive function were assessed by metagenomic sequencing and the MATRICS Consensus Cognitive Battery (MCCB), respectively. Compared with the CW adolescents, the SD group showed higher relative abundance of <i>Spirochaetes, Synergistetes, Spirochaetia, Synergistia,</i><i> </i><i>Spirochaetales, Rhizobiales,</i><i> </i><i>Synergistales, Thermoanaerobacterales, Rhodospirillales, </i><i>Synergistaceae</i> and <i>Oxalobacteraceae</i> at four levels. The Spatial Span scores were higher in the SD group compared to the CW groups. Moreover, EggNOG analyses showed a significant negative correlation of the intracellular trafficking secretion and vesicular transport with the Spatial Span scores. The KEGG pathway of the neurodegenerative diseases and translation was depleted in the microbiome of adolescents with SD. The higher abundance of <i>Spirochaetes, Spirochaetia</i> and <i>Spirochaetales</i> were the best predictors of SD in adolescents. Our findings suggest that gut microbiome dysbiosis, depressive symptoms, and cognitive influences co-occur in adolescents with SD, which may play a crucial role in the pathogenesis of SD and cognitive function in adolescent. Gut microbiome may serve as a potential biomarker for the identification and treatment of adolescents with SD.
DOI: 10.6084/m9.figshare.13125551.v1
title: Candy sales 2020

description: Data scraped from National Retail Federation webpage for 2020.
DOI: 10.6084/m9.figshare.14542434.v1
title: RGB Image Dataset

description: Curated RGB image dataset for our analysis, splited into training and evalutaion set. <br>Based on ImageNet ILSVRC dataset (Russakovsky O, Deng J, Su H, Krause J, Satheesh S, Ma S, Huang Z, Karpathy A, Khosla A, Bernstein M, Berg AC, 2015).
DOI: 10.6084/m9.figshare.24088632.v3
title: 1000G LD reference data

description: 1000G.EUR.QC.bim/fam/bed are the 1000G dataset. fourier_ls-all.bed is the block file.ld_1kg_EUR_hm3_shrink.h5 is the LD file.
DOI: 10.6084/m9.figshare.7940597.v1
title: BITR-18-096.R2_data

description: Dataset from the manuscript "Satellite image texture for the assessment of tropical anuran communities"