cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.5696248
title: The More Doctors Program: documentary analysis of critical events and positioning of social actors

description: One of the challenges in consolidating primary health care, which is a priority strategy for reorienting the healthcare model in Brazil, is the difficulty of supplying and retaining health professionals, especially physicians, throughout the country. This study consists of a documentary analysis of the formulation and implementation processes of the More Doctors Program from 2013 (time of publication of Law No. 12871/2013, which created the MDP) to 2015. Through the selected publications, it was possible to map critical events, interests and identification of divergent positions among social actors (allies, opponents or indifferent) involved in the stages of formulating proposals and implementing the program. The analysis indicated that the MDP generally represented a step forward in providing expanded access to health in Brazil.
DOI: 10.6084/m9.figshare.5696248.v1
title: The More Doctors Program: documentary analysis of critical events and positioning of social actors

description: One of the challenges in consolidating primary health care, which is a priority strategy for reorienting the healthcare model in Brazil, is the difficulty of supplying and retaining health professionals, especially physicians, throughout the country. This study consists of a documentary analysis of the formulation and implementation processes of the More Doctors Program from 2013 (time of publication of Law No. 12871/2013, which created the MDP) to 2015. Through the selected publications, it was possible to map critical events, interests and identification of divergent positions among social actors (allies, opponents or indifferent) involved in the stages of formulating proposals and implementing the program. The analysis indicated that the MDP generally represented a step forward in providing expanded access to health in Brazil.
DOI: 10.6084/m9.figshare.5696242
title: Expression of EGF receptors in canine prostate with proliferative inflammatory atrophy and carcinoma

description: ABSTRACT: Gene expression of ErbB1 and ErbB2, and immunostaining of EGFR (Her1) and Her2 (c-erbB-2) were evaluated in this study to ascertain whether these receptors are involved in the evolution of canine premalignant and malignant prostatic lesions, as proliferative inflammatory atrophy (PIA) and prostatic carcinoma (PC). With regards to the intensity of EGFR immunostaining, there was no difference between normal prostatic tissue and tissues with PIA or PC. In relation to Her2 immunostaining, there were differences between normal prostatic tissue and those with PIA and PC, as also differences between prostates with PIA and PC. There was no correlation between EGFR and Her2 immunostaining. ErbB1 gene product was detected in two normal tissue samples, in one with PIA, and in all samples with PC. ErbB2 mRNA was recorded in two canine samples with PIA, in all with PC, but was not detected in normal prostatic tissue. It was concluded that EGFR and Her2 play roles in canine PIA and PC, suggesting that those receptors may be involved in canine prostatic carcinogenesis.
DOI: 10.6084/m9.figshare.5696242.v1
title: Expression of EGF receptors in canine prostate with proliferative inflammatory atrophy and carcinoma

description: ABSTRACT: Gene expression of ErbB1 and ErbB2, and immunostaining of EGFR (Her1) and Her2 (c-erbB-2) were evaluated in this study to ascertain whether these receptors are involved in the evolution of canine premalignant and malignant prostatic lesions, as proliferative inflammatory atrophy (PIA) and prostatic carcinoma (PC). With regards to the intensity of EGFR immunostaining, there was no difference between normal prostatic tissue and tissues with PIA or PC. In relation to Her2 immunostaining, there were differences between normal prostatic tissue and those with PIA and PC, as also differences between prostates with PIA and PC. There was no correlation between EGFR and Her2 immunostaining. ErbB1 gene product was detected in two normal tissue samples, in one with PIA, and in all samples with PC. ErbB2 mRNA was recorded in two canine samples with PIA, in all with PC, but was not detected in normal prostatic tissue. It was concluded that EGFR and Her2 play roles in canine PIA and PC, suggesting that those receptors may be involved in canine prostatic carcinogenesis.
DOI: 10.6084/m9.figshare.5696239
title: The era of congregations - social thought, education and Catholicism

description: Abstract The national policy has placed at the center of discussions the relations, in Brazil, between the social thought and the religious ideals of various denominations. With a strong participation in political spaces, churches, elect education, sexuality and secularism as the main themes of the debate. This article analyzes the strategies of the Catholic Church in accordance with sectors of the Brazilian elites to develop the evangelization of culture during the twentieth century, the effects of which mark the current political scene. The objects of analysis of this research are the immigration of the congregations to Brazil and the process of restructuring and modernization of the Church. The study is rooted in a database, under construction, in which these religious associations and their social projects are mapped.
DOI: 10.6084/m9.figshare.5696239.v1
title: The era of congregations - social thought, education and Catholicism

description: Abstract The national policy has placed at the center of discussions the relations, in Brazil, between the social thought and the religious ideals of various denominations. With a strong participation in political spaces, churches, elect education, sexuality and secularism as the main themes of the debate. This article analyzes the strategies of the Catholic Church in accordance with sectors of the Brazilian elites to develop the evangelization of culture during the twentieth century, the effects of which mark the current political scene. The objects of analysis of this research are the immigration of the congregations to Brazil and the process of restructuring and modernization of the Church. The study is rooted in a database, under construction, in which these religious associations and their social projects are mapped.
DOI: 10.6084/m9.figshare.5696236
title: NARRATIVES OF RACIAL QUOTA BENEFICIARIES ABOUT THEIR EXPERIENCES AT THE UNIVERSITY

description: ABSTRACT The article resulted from a research focused on the academic trajectories of students who entered the system through racial quotas in the Universidade Federal do Pará (UFPA), considering the analysis of the meanings attributed by students themselves to this experience they lived. In the field of studies about the functioning of racial affirmative actions, the research analyzes the narratives of thirteen students who entered UFPA through the racial quota and have already graduated or are close to complete their graduation. The conclusions of this study suggest that, regarding the students interviewed, the program of UFPA has been effective in providing these young people with access and successful stay at the university, although they still face financial difficulties, problems to access cultural benefits and prejudice, both because they are racial quota beneficiaries and because they are black.
DOI: 10.6084/m9.figshare.5696236.v1
title: NARRATIVES OF RACIAL QUOTA BENEFICIARIES ABOUT THEIR EXPERIENCES AT THE UNIVERSITY

description: ABSTRACT The article resulted from a research focused on the academic trajectories of students who entered the system through racial quotas in the Universidade Federal do Pará (UFPA), considering the analysis of the meanings attributed by students themselves to this experience they lived. In the field of studies about the functioning of racial affirmative actions, the research analyzes the narratives of thirteen students who entered UFPA through the racial quota and have already graduated or are close to complete their graduation. The conclusions of this study suggest that, regarding the students interviewed, the program of UFPA has been effective in providing these young people with access and successful stay at the university, although they still face financial difficulties, problems to access cultural benefits and prejudice, both because they are racial quota beneficiaries and because they are black.
DOI: 10.6084/m9.figshare.5696224
title: Microscopic aspects of electrosensory system on the partially euryhaline lesser guitarfish

description: ABSTRACT The electrosensory system on elasmobranchs consists of subcutaneous electroreceptor organs known as ampullae of Lorenzini. The present study investigated the ampullae of Lorenzini morphology of the lesser guitarfish Zapteryx brevirostris, using light microscopy and scanning electron microscopy. The pore number found in the ventral skin surface is much higher than that found in the dorsal portion, characteristic of species that inhabit the euphotic zone. Under light microscopy it was possible to observe that the wall canal consists of a single layer of squamous epithelial cells. The canal features distal expansion, where the ampullae are located with up to six alveoli. The sensory epithelium of ampullae is composed by cubic cells, with oval nucleus, restricted to the interior of the alveoli. With analysis the clusters under scanning electron microscopy, it was possible to observe the structure and the random arrangement of individual ampullae, canals and nerves. The distribution of dorsal and ventral pores and ampullae in Z. brevirostris resembled those of the same family. The number of alveoli per ampullae was similar to that found in euryhaline elasmobranchs species, suggesting that the morphological organization in Z. brevirostris is linked to its possible evolutionary transitory position among batoids.
DOI: 10.6084/m9.figshare.5696224.v1
title: Microscopic aspects of electrosensory system on the partially euryhaline lesser guitarfish

description: ABSTRACT The electrosensory system on elasmobranchs consists of subcutaneous electroreceptor organs known as ampullae of Lorenzini. The present study investigated the ampullae of Lorenzini morphology of the lesser guitarfish Zapteryx brevirostris, using light microscopy and scanning electron microscopy. The pore number found in the ventral skin surface is much higher than that found in the dorsal portion, characteristic of species that inhabit the euphotic zone. Under light microscopy it was possible to observe that the wall canal consists of a single layer of squamous epithelial cells. The canal features distal expansion, where the ampullae are located with up to six alveoli. The sensory epithelium of ampullae is composed by cubic cells, with oval nucleus, restricted to the interior of the alveoli. With analysis the clusters under scanning electron microscopy, it was possible to observe the structure and the random arrangement of individual ampullae, canals and nerves. The distribution of dorsal and ventral pores and ampullae in Z. brevirostris resembled those of the same family. The number of alveoli per ampullae was similar to that found in euryhaline elasmobranchs species, suggesting that the morphological organization in Z. brevirostris is linked to its possible evolutionary transitory position among batoids.
DOI: 10.6084/m9.figshare.5696218
title: Evaluation of phenolic compounds and lipid-lowering effect of Morus nigra leaves extract

description: ABSTRACT Morus nigra L. (Moraceae) is a tree known as black mulberry and the leaves are used in folk medicine in the treatment of diabetes, high cholesterol and menopause symptoms. The aim of this study was to evaluate the M. nigra leaves phytochemical profile in different extractions and the hypolipidemic effect of the infusion comparing to the fenofibrate. Morus nigra infusion (MN) showed higher amounts of phenolics and flavonoids (83.85 mg/g and 79.96 µg/g, respectively), as well as antioxidant activity (83.85%) than decoction or hydromethanolic extracts. Although, decoction showed the best result for ascorbic acid (4.35 mg/100 g) than hydromethanolic or infusion (2.51 or 2.13 mg/100 g, respectively). The phenolic acids gallic, chlorogenic and caffeic and the flavonoids quercetin, rutin and catechin were found in the M. nigra extracts. Hyperlipidemic rats treated with 100, 200 or 400 mg/kg of MN decreased serum cholesterol, triglycerides and normalized lipoproteins. Furthermore, MN inhibited lipid peroxidation in liver, kidney and brain of hyperlipidemic rats. This study provides evidence that M. nigra leaves extracts are rich in polyphenols, mainly chlorogenic acid, which normalized hyperlipidemic disturbance. The results suggest a potential therapeutic effect of the M. nigra leaves infusion on dislipidemic condition and related oxidative stress.
DOI: 10.6084/m9.figshare.5696215
title: Commelina Species Control with Desiccants Alone and in Mixtures

description: ABSTRACT: The objective of this study was to evaluate the chemical control of the species C. benghalensis and C. erecta with desiccants alone and mixtures, as well as the spreading of spray droplets on the leaf surfaces. The experimental design was completely randomized in a 2 x 16 factorial arrangement with four replications, totaling 32 treatments and 128 plots. The first factor is related to the species C. benghalensis and C. erecta and the second factor corresponds to the treatments carfentrazone-ethyl in doses of 15, 30, 60 g ha-1, which added 0.5% v v-1 adhesive spreader; glufosinate ammonium at doses of 100, 200, 400 g ha-1, added 0.5% v v-1 mineral oil; glyphosate at 240, 480, 960 g ha-1; carfentrazone-ethyl + glufosinate ammonium in doses of 100, 200, 400 g ha-1 being added 0.5% v v-1 of mineral oil; carfentrazone-ethyl + glufosinate ammonium in doses of 15+100, 30+200, 60+400 g ha-1 being added 0.5% v v-1 of mineral oil; and carfentrazone-ethyl + glyphosate at 15+240, 30+480, 60+960 g ha-1, which added 0.5% v v-1 of a spreader and sticker agent, besides the controls without applications. There was a difference in control between species for desiccants applied alone. For C. benghalensis there was an excellent control (&gt; 85%) for all the treatments. However, for C. erecta the best controls involved glufosinate ammonium (200 and 400 g ha-1), carfentrazone-ethyl (30 and 60 g ha-1), glyphosate (960 g ha-1) and all mixtures with an average of 96.6% in the control.
DOI: 10.6084/m9.figshare.5696215.v1
title: Commelina Species Control with Desiccants Alone and in Mixtures

description: ABSTRACT: The objective of this study was to evaluate the chemical control of the species C. benghalensis and C. erecta with desiccants alone and mixtures, as well as the spreading of spray droplets on the leaf surfaces. The experimental design was completely randomized in a 2 x 16 factorial arrangement with four replications, totaling 32 treatments and 128 plots. The first factor is related to the species C. benghalensis and C. erecta and the second factor corresponds to the treatments carfentrazone-ethyl in doses of 15, 30, 60 g ha-1, which added 0.5% v v-1 adhesive spreader; glufosinate ammonium at doses of 100, 200, 400 g ha-1, added 0.5% v v-1 mineral oil; glyphosate at 240, 480, 960 g ha-1; carfentrazone-ethyl + glufosinate ammonium in doses of 100, 200, 400 g ha-1 being added 0.5% v v-1 of mineral oil; carfentrazone-ethyl + glufosinate ammonium in doses of 15+100, 30+200, 60+400 g ha-1 being added 0.5% v v-1 of mineral oil; and carfentrazone-ethyl + glyphosate at 15+240, 30+480, 60+960 g ha-1, which added 0.5% v v-1 of a spreader and sticker agent, besides the controls without applications. There was a difference in control between species for desiccants applied alone. For C. benghalensis there was an excellent control (&gt; 85%) for all the treatments. However, for C. erecta the best controls involved glufosinate ammonium (200 and 400 g ha-1), carfentrazone-ethyl (30 and 60 g ha-1), glyphosate (960 g ha-1) and all mixtures with an average of 96.6% in the control.
DOI: 10.6084/m9.figshare.5696212
title: Plant species diversity in a Neotropical wetland: patterns of similarity, effects of distance, and altitude

description: ABSTRACT The Brazilian Pantanal is an extensive wetland with heterogeneous habitats, primarily due to the river-floodplain system and plants with differential adaptations and reproductive strategies. Factors such as altitude, distance among plant formations, and flood pulse must be considered to better understand its diversity. Aiming to assess the influence of biogeographic patterns in this system, we analyzed the floristic composition of six areas along the Paraguay River, including residual relieves, verifying the pattern of similarity, and effects of distance and altitude. We recorded 356 species in 87 families, mostly perennial (75%), and some annuals (15%) and pluriannuals (5%). Herbaceous plants were the most represented (48%), followed by arboreal (23%), shrubby (15%) and epiphytic (14%) habits, only 12% being endemic to Brazil. The studied areas showed low floristic similarity, but higher resemblance of species between neighboring areas, and no relation with altitude. The upper Paraguay River is diverse, with high spatial variability of species, predominantly perennial. The river-floodplain connectivity may be a determinant factor in species richness and occurrence of endemic species.
DOI: 10.6084/m9.figshare.5696209
title: Effects of temperature on the feeding behavior of Alabama argillacea (Hübner) (Lepidoptera: Noctuidae) on Bt and non-Bt cotton plants

description: ABSTRACT The host acceptance behavior and environmental factors as temperature affect the feeding behavior of Lepidoptera pests. Thus, they must be considered in studies about the risk potential of resistance evolution. The current study sets the differences in the feeding behavior of neonate Alabama argillacea (Hübner) (Lepidoptera: Noctuidae) larvae exposed to Bt and non-Bt cotton plants, under different temperatures and time gap after hatching. Two cotton cultivars were used: the Bt (DP 404 BG - bollgard) and the non-transformed isoline, DP 4049. We found that the feeding behavior of neonate A. argillacea is significantly different between Bt and non-Bt cotton. Based on the number of larvae with vegetal tissue in their gut found on the plant and in the organza as well as on the amount of vegetal tissue ingested by the larvae. A. argillacea shows feeding preference for non-Bt cotton plants, in comparison to that on the Bt. However, factors such as temperature and exposure time may affect detection capacity and plant abandonment by the larvae and it results in lower ingestion of vegetal tissue. Such results are relevant to handle the resistance of Bt cotton cultivars to A. argillacea and they also enable determining how the cotton seeds mix will be a feasible handling option to hold back resistance evolution in A. argillacea populations on Bt cotton, when it is compared to other refuge strategies. The results can also be useful to determine which refuge distribution of plants is more effective for handling Bt cotton resistance to A. argillacea.
DOI: 10.6084/m9.figshare.5696209.v1
title: Effects of temperature on the feeding behavior of Alabama argillacea (Hübner) (Lepidoptera: Noctuidae) on Bt and non-Bt cotton plants

description: ABSTRACT The host acceptance behavior and environmental factors as temperature affect the feeding behavior of Lepidoptera pests. Thus, they must be considered in studies about the risk potential of resistance evolution. The current study sets the differences in the feeding behavior of neonate Alabama argillacea (Hübner) (Lepidoptera: Noctuidae) larvae exposed to Bt and non-Bt cotton plants, under different temperatures and time gap after hatching. Two cotton cultivars were used: the Bt (DP 404 BG - bollgard) and the non-transformed isoline, DP 4049. We found that the feeding behavior of neonate A. argillacea is significantly different between Bt and non-Bt cotton. Based on the number of larvae with vegetal tissue in their gut found on the plant and in the organza as well as on the amount of vegetal tissue ingested by the larvae. A. argillacea shows feeding preference for non-Bt cotton plants, in comparison to that on the Bt. However, factors such as temperature and exposure time may affect detection capacity and plant abandonment by the larvae and it results in lower ingestion of vegetal tissue. Such results are relevant to handle the resistance of Bt cotton cultivars to A. argillacea and they also enable determining how the cotton seeds mix will be a feasible handling option to hold back resistance evolution in A. argillacea populations on Bt cotton, when it is compared to other refuge strategies. The results can also be useful to determine which refuge distribution of plants is more effective for handling Bt cotton resistance to A. argillacea.
DOI: 10.6084/m9.figshare.5696200
title: Requiem for a neurologist: the funeral rites of Jean-Martin Charcot

description: ABSTRACT Jean-Martin Charcot, the founder of modern neurology and leading figure in international neurology in the 19th century, died on August 16, 1893, in the province of Morvan in the French countryside, at the age of 67. The funeral service was held in Paris at the La Salpêtrière Hospital, and Charcot was buried in Montmartre cemetery in the same city.
DOI: 10.6084/m9.figshare.5696200.v1
title: Requiem for a neurologist: the funeral rites of Jean-Martin Charcot

description: ABSTRACT Jean-Martin Charcot, the founder of modern neurology and leading figure in international neurology in the 19th century, died on August 16, 1893, in the province of Morvan in the French countryside, at the age of 67. The funeral service was held in Paris at the La Salpêtrière Hospital, and Charcot was buried in Montmartre cemetery in the same city.
DOI: 10.6084/m9.figshare.5696197
title: Thiol/disulfide status regulates the activity of thiol-containing kinases related to energy homeostasis in rat kidney

description: ABSTRACT Considering that thiol-containing enzymes like kinases are critical for several metabolic pathways and energy homeostasis, we investigated the effects of cystine dimethyl ester and/or cysteamine administration on kinases crucial for energy metabolism in the kidney of Wistar rats. Animals were injected twice a day with 1.6 µmol/g body weight cystine dimethyl ester and/or 0.26 µmol/g body weight cysteamine from the 16th to the 20th postpartum day and euthanized after 12 hours. Pyruvate kinase, adenylate kinase, creatine kinase activities and thiol/disulfide ratio were determined. Cystine dimethyl ester administration reduced thiol/disulfide ratio and inhibited the kinases activities. Cysteamine administration increased the thiol/disulfide ratio and co-administration with cystine dimethyl ester prevented the inhibition of the enzymes. Regression between the thiol/disulfide ratio, and the kinases activities were significant. These results suggest that redox status may regulate energy metabolism in the rat kidney. If thiol-containing enzymes inhibition and oxidative stress occur in patients with cystinosis, it is possible that lysosomal cystine depletion may not be the only beneficial effect of cysteamine administration, but also its antioxidant and thiol-protector effect.