cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17632/8gfxch4kb9
title: HIV-1 env does not enable the development of protective broadly neutralizing antibodies is an experimental autoimmune encephalomyelitis mouse model

description: DOI for this work is: 10.3389/fimmu.2021.771359
Published in 2021 by Lucia Lopalco et al.
Recent studies showed that immunological tolerance may restrict the development of Env-specific autoreactive broadly neutralizing antibodies. This evidence is consistent with the finding that Env immunization of a systemic lupus erythematosus (SLE) murine model produced antibodies that neutralize tier 2 HIV-1 strains. In this study, we address the possibility of eliciting neutralizing anti-Env antibodies in other autoimmune diseases such as multiple sclerosis (MS). While, as reported for SLE, we showed for the first time that a small number of HIV-1 negative, relapsing remitting MS patients exhibited antibodies with neutralizing properties, our attempts at inducing those antibodies in a EAE mouse model of MS failed. The success in eliciting Env-specific neutralizing antibodies might be related to the specific characteristics of the autoimmune disease, or it might rely in improving the vaccination design. Studies using mouse models are useful to gain insight in how HIV-specific neutralizing antibody responses are regulated in order to develop a protective HIV-1 vaccine. The raw data of each figure reported in the manuscript is reported here. In total we have 6 different files.
DOI: 10.17632/9tdhvryz5n
title: LINF_200005800

description: protein of unknown function - conserved
Leishmania infantum (strain JPCM5)
DOI: 10.17632/bsc8fmzcfw
title: Data of Survey on Cooking Oil Preferences: A case study in Phnom Penh, Cambodia

description: The raw data and analyzed data obtained from an online survey using Google form. The survey was implemented from 15 March to 19 May 2021 by using an online questionnaire to seek information about consumer preferences of cooking oil for popularity, consumption, and factors driven consumer preferences.
DOI: 10.17632/bvsrdfngdk
title: Supplementary Table I. Diagnostic codes for relevant conditions

description: This is a supplemental table containing diagnostic codes which were used for this study.
DOI: 10.17632/cd5pwwc2sx
title: Exploring the Professional Identity of Advanced Clinical Practitioners: Constructivist ethnographic qualitative research study

description: Background: The Advanced clinical practitioner, is a healthcare professional who has undertaken additional years of Master's level training, acquired new skills and capabilities and developed as an autonomous practitioner. 

Purpose: Whilst several studies have appraised and analysed this professional role, there are limited empirical studies that have explored professional identity formation within this group. This paper explores this evolution. 

Method: Through a constructivist ethnographic approach, we conducted semi-structured interviews with seven qualified Advanced clinical practitioners within a secondary care setting. We identified key issues regarding professional identity formation. 

Results: Our research highlights the lack of role recognition which acts as a barrier to Advanced clinical practitioner professional identity formation and further development. 

Conclusion: Professional identity is an intertwined concept and without enhancing all the components involved in identity formation, the solo individual component cannot enact the formation of a new identity if this is not legitimated by the other components too, including personal, socio-cultural, educational and institutional.
DOI: 10.17632/fx8656xbgb
title: Data on Pine  Needle Extraction and Bioactivity Testing

description: The current study employed solid-liquid extraction using hexane to separate biomolecules from pine needles and GC/ MS QP2010 PLUS, Shimadzu for their identification. The solid and liquid cultures for microbial growth and UV-Vis to measure growth. Protein extraction was done using physical-chemical methods, separation using gel electrophoresis and analysis by MALDI-QUAD-TOF-MS-MS followed by Mascot software search for library comparison.
DOI: 10.17632/g4ckg4s3x8
title: Evaluation of a CRISPR enhanced metagenomic NGS test for pandemic preparedness. Chan and Siddique et al

description: Chan and Siddique et al. 2023. Supplemental Tables S1 to S7. Please refer to the Cell Reports Methods manuscript for a full list of authors and methods.
DOI: 10.17632/g6gsfn9k9j
title: SNP markers located in the confidence intervals of mapped QTLs for grain protein content (GPC), yield per spike (YPS) and thousand-kernel wheight (TKW) in 135 durum RILs derived by the inter-specific cross “02-5B-318 × Saragolla”.

description: Supplementary Table 1 lists SNP markers located in the confidence intervals of mapped QTLs for GPC, which were searched for a putative function related to wheat seed quality and quantity (storage protein synthesis/accumulation). Each SNP is annotated with the corresponding marker name, identification code, SNP type, nucleotide sequence/length, and chromosomal position on the durum wheat genetic linkage map developed by Giancaspro et al (2016).

Supplementary Table 2 lists SNP markers located in the confidence intervals of mapped QTLs for GYS, which were searched for a putative function related to wheat productivity (grain yield components). Each SNP is annotated with the corresponding marker name, identification code, SNP type, nucleotide sequence/length and chromosomal position on the durum wheat genetic linkage map developed by Giancaspro et al (2016).

Supplementary Table 3 lists SNP markers located in the confidence intervals of mapped QTLs for TKW, which were searched for a putative function related to wheat productivity (grain yield components). Each SNP is annotated with the corresponding marker name, identification code, SNP type, nucleotide sequence/length and chromosomal position on the durum wheat linkage genetic map developed by Giancaspro et al (2016).
DOI: 10.17632/hg3y4v2cbf
title: kremen1 regulates lateral line hair cell regeneration

description: Raw cell counts for the manuscript "Kremen1 regulates the regenerative capacity of support cells and mechanosensory hair cells in the zebrafish lateral line:
DOI: 10.17632/hjdh2kg9db
title: HCF subchannel data

description: This is the database of the article "Numerical Study on the transverse mixing Characteristics of the Flow Sweeping in Helical cruciform Rod Bundle"
DOI: 10.17632/k78wgm58x4
title: AlphaResearch - SEC filings, 10K, 10Q search

description: If you do any search on SEC filings such as form 10K, 10Q, etc.., AlphaResearch should be your tools. They use advanced AI to make searching millions of long document a breeze. No more spending hours scrolling through a document just to find one detail you are interested in.

To get started, download this dataset which contains the Income Statement of Apple.
DOI: 10.17632/kg5wf3frtn
title: Data for "Disparities in PM2.5 Exposure in China"

description: Data for "Disparities in PM2.5 Exposure in China"
DOI: 10.17632/kkf4zdz2x7
title: Broad cross-reactivity across sarbecoviruses exhibited by a subset of COVID-19 donor-derived neutralizing antibodies. Jette et al

description: Supplemental Movie for publication Broad cross-reactivity across sarbecoviruses exhibited by a subset of COVID-19 donor-derived neutralizing antibodies by Jette et al 2021
DOI: 10.17632/nkh44zr4nj
title: ArcGIS-based Equilibrium Game Policy and Protected Area Planning in the Masai Mara Region_Data

description: ArcGIS-based Equilibrium Game Policy and Protected Area Planning in the Masai Mara Region_Data
DOI: 10.17632/nxmx5w8y63
title: Reservoir Inflow and SWE

description: Historical collection of snow water equivalent (SWE) data from National Resource Conservation Service (NRCS) snow telemetry monitoring stations and calculated reservoir inflow for Upper Stillwater reservoir from the Central Utah Water Conservancy District (CUWCD). SWE is measured in units of inches (in) and reservoir inflow is calculated in units of cubic feet per second (cfs). Daily reservoir inflow is calculated from CUWCD Supervisory Control and Data Aquisition (SCADA) data considering the change in reservoir elevation to determine change in storage volume compared to monitored losses (e.g. seepage and evaporation) and releases (e.g. Rock Creek and Stillwater Tunnel).
DOI: 10.17632/p8g3znzspb
title: Symptomscore vs cytokines

description: Context
Patients with palliative-stage cancer often suffer from a variety of debilitating symptoms which have been shown to appear in clusters. It is suggested that cytokines cause many such symptoms, and elevated cytokine production has been shown to correlate with symptoms. However, symptom clusters have not been thoroughly analyzed in relation to cytokine clusters.

Objectives
To identify symptom clusters and cytokine clusters in Swedish cancer patients, and to investigate correlations between the identified symptom clusters and cytokine clusters.

Methods
A questionnaire (EORTC QLQ-C15-PAL) was completed by 110 cancer patients, with blood samples taken at two time points four weeks apart. MSD assays were used to analyze 23 cytokines. Statistical analysis was performed using principal component analysis of symptoms and cytokines, followed by correlation analysis of the obtained clusters.

Results
Three symptom clusters were identified: i) pain-sleep disorder, ii) gastro-intestinal-fatigue, iii) physical functioning. The cytokines were divided into three clusters that can be characterized as i) pro-tumorigenic, ii) cell-mediated immune response and iii) proinflammatory. At the second time point, a fourth cytokine cluster was isolated iv) immunostimulation. Correlations were found at both time points between the proinflammatory cytokine cluster and the physical functioning symptom cluster, and at the week four time point between the proinflammatory cytokine cluster and the gastro-intestinal-fatigue symptom cluster. 

Conclusion
We show a correlation between symptom clusters and the proinflammatory cytokine cluster. Proinflammatory cytokines are known to cause symptoms that resemble palliative cancer symptoms. Increased knowledge of biochemical processes and their effect on patients’ wellbeing may give clues for counteracting symptoms that affect quality of life in palliative cancer care.
DOI: 10.17632/pcpd4vwv9f
title: Coal production logistics system

description: resource allocation data
DOI: 10.17632/rz9dtfv5wp
title: THWang_sulfide_data_2023

description: Data for precipitation experiments and XRD analysis
DOI: 10.17632/sw6ph9f3dc
title: Data for: Heavy ion radiation-induced DNA damage mediates apoptosis via Rpl27a-Rpl5-MDM2-p53/E2F1 signaling pathway in mouse spermatogonia

description: A total of 360 differential proteins were identified; 90 were upregulated and 270 were downregulated. A total of 101 differential mRNAs were identified; 46 were upregulated and 55 were downregulated.
DOI: 10.17632/t7zcvp4yvh
title: Depth Profiling of Implanted D+ in Silicates: Contribution of Solar Wind Protons to Water in the Moon and Terrestrial Planets

description: Research data of "Depth Profiling of Implanted D+ in Silicates: Contribution of Solar Wind Protons to Water in the Moon and Terrestrial Planets "
DOI: 10.17632/tw35dgpk67
title: A Bacterial Bile Acid Metabolite Modulates Treg Activity through the Nuclear Hormone Receptor NR4A1. Li, Hang, et al.

description: Spectral data for all synthesized compounds, 3-oxoalloLCA, 3-oxo-4Δ-LCA, 4Δ-isoLCA.
DOI: 10.17632/www78j3w73
title: Dataset of web accessibility evaluation of Russian-language MOOCs in computer science and programming, 2020

description: English
The dataset contains the results of automatic and expert digital accessibility assessment of Russian-language MOOCs in computer science and programming. The study was carried out in 2020, the content of 65 MOOCs was analyzed. Automatic web accessibility assessment was performed using the WAVE web accessibility evaluation tool (WebAIM, USA), expert assessment – using author's checklists based on WCAG 2.1. The dataset is presented in two languages: English (Web_Accessibility_Of_CS_MOOCs_EN.xlsx) and Russian (Web_Accessibility_Of_CS_MOOCs_RU.xlsx).

Русский
Набор данных содержит результаты автоматической и экспертной оценки цифровой доступности русскоязычных МООК по компьютерным наукам и программированию. Исследование выполнялось в 2020 году, проанализирован контент 65 МООК. Автоматическая оценка веб-доступности выполнена с помощью инструмента WAVE (WebAIM, США), экспертная оценка – с помощью авторских чек-листов, основанных на WCAG 2.1. Набор данных представлен на английском (Web_Accessibility_Of_CS_MOOCs_EN.xlsx) и русском (Web_Accessibility_Of_CS_MOOCs_RU.xlsx) языках.
DOI: 10.17632/yhjhwfj96h
title: Data - Geotechnics of Arboletes soft cliffs: index properties and triaxial tests

description: We explored the geotechnical characteristics of cliff base rocks (gray mudstone) at Arboletes to shed light on how rock mechanics influence soft-cliff retreat. Despite apparent similar characteristics from descriptive studies, index properties differed and mechanical tests (monotonic and dynamic triaxial test) showed the mechanical response was different. We obtained the data with a  triaxial chamber at the Soils Laboratory of EAFIT University after collecting samples at two sites in Arboletes town (Department of Antioquia), Caribbean Coast of Colombia. The files include: (1) a text with the test results for index properties, and (2) a spreadsheet with data used to create Figures that show differences in mechanical responses.
DOI: 10.17632/z3frp6nw4s
title: Supporting information for 'In-situ synthesis method of Three-Dimensional Silicon/Reduced Graphene Oxide semiconductor nanohybrids for efficient electromagnetic absorption'

description: Supporting information for 'In-situ synthesis method of Three-Dimensional Silicon/Reduced Graphene Oxide semiconductor nanohybrids for efficient electromagnetic absorption'
DOI: 10.17632/3264fw5m5k
title: Data for: Calcaneal Bone Graft Procedures: An Analysis of Post-Surgical Complications

description: Excel data set.
DOI: 10.17632/44k3x7fwcm
title: Data for: Origin of magmatic harzburgite as a result of boninite magma evolution – An illustration using layered harzburgite-dunite cumulate from the Troodos ophiolite complex

description: Data of the interlayered ultramafic cumulate and boninite in the Troodos ophiolite.
DOI: 10.17632/4x6hy98krb
title: Recapitulation of cell-like KRAS4b membrane dynamics on complex biomimetic membranes

description: Single particle tracking images of KRAS4b FME S106C-JF646 on supported lipid bilayer
DOI: 10.17632/7jkmnbb9gc
title: Citizen Science with Undergraduate Wildlife Students

description: Data collected in 2016 study of undergraduate students participating in a citizen science research experience in a Wildlife Management Techniques course.
DOI: 10.17632/8j45xfhh3y
title: LINF_320021650

description: DNA helicase | PIF4
Leishmania infantum (strain JPCM5)
DOI: 10.17632/bwdj9tvssg
title: RNF168 E3 ligase participates in ubiquitin signaling and recruitment of SLX4 during DNA crosslink repair. Katsuki et al

description: SLX4/FANCP is a key Fanconi anemia (FA) protein and a DNA repair scaffold for incision around a DNA interstrand crosslink (ICL) by its partner XPF nuclease. The tandem UBZ4 ubiquitin-binding domains of SLX4 are critical for the recruitment of SLX4 to damage sites, likely via binding to K63-linked polyubiquitin chains. However, the identity of the ubiquitin E3 ligase that mediates SLX4 recruitment remains unknown. Using siRNA screening with a GFP-tagged N-terminal half of SLX4 (termed SLX4-N), we identified RNF168 E3 ligase as a critical factor for mitomycin C (MMC)-induced SLX4 foci formation. RNF168 and GFP-SLX4-N colocalized in MMC-induced ubiquitin foci. Accumulation of SLX4-N at psoralen-laser ICL tracks or of endogenous SLX4 at Digoxigenin-psoralen/UVA ICL was dependent on RNF168. Finally, we found that RNF168 was epistatic with SLX4 in promoting MMC tolerance. We conclude that RNF168 is a critical component of the signal transduction that recruits SLX4 to ICL damage.
DOI: 10.17632/dfw8r794ph
title: Data for FiNuTyper: design and validation of an automated deep learning-based platform for simultaneous fiber and nucleus type analysis in human skeletal muscle

description: Abstract

Aim:
While manual quantification is still considered the gold standard for skeletal muscle histological analysis, it is time-consuming and prone to investigator bias. To address this challenge, we assembled an automated image analysis pipeline, FiNuTyper (Fiber and Nucleus Typer).

Methods:
We integrated recently developed deep learning-based image segmentation methods, optimized for unbiased evaluation of fresh and postmortem human skeletal muscle,  and utilized SERCA1 and SERCA2 as type-specific myonucleus and myofiber markers after validating them against the traditional use of MyHC isoforms. 

Results:
Parameters including cross-sectional area, myonuclei per fiber, myonuclear domain, central myonuclei per fiber, and grouped myofiber ratio were determined in a fiber type-specific manner, revealing that a large degree of sex- and muscle-related heterogeneity could be detected using the pipeline. Our platform was also tested on pathological muscle tissue (ALS, IBM) and adapted for the detection of other resident cell types (leukocytes, satellite cells, capillary endothelium). 

Conclusion:
In summary, we present an automated image analysis tool for the simultaneous quantification of myofiber and myonuclear types, to characterize the composition and structure of healthy and diseased human skeletal muscle.

Keywords
Skeletal muscle, myonuclei, myofibers, SERCA, automated image analysis
DOI: 10.17632/f967jhy5n4
title: Data For: CO2-Induced Thermal Maturation in Shale and Implications for CO2 Utilization and Storage

description: Data for Manuscript submitted to Journal of CO2 Utilization
DOI: 10.17632/fnxgxgmcbr
title: Supplemental table 1. Pemphigus Disease Area Index scores by prior suggested cutoff scores.

description: Pemphigus Disease Area Index (PDAI) scores by prior suggested cutoff scores.
DOI: 10.17632/g7g5b5z6p8
title: Operacionalización de variables 

description: Cuando un fenómeno o problema no puede ser medido directamente, es necesario operacionalizar las variables. Esto con el fin de obtener datos empíricos (matemáticos) que permitan dar cuenta de la objetividad del fenómeno. 
El presente texto muestra dos tablas que corresponden a un ejemplo de formato para operacionalizar las variables. Esto es, el modo en el que se organizan las variables que son relevantes y de interés para la investigación. Se organiza en este formato para poder tener una comprensión y vista más práctica al momento de pensar y programar las operaciones estadísticas y matemáticas (métodos), que habrán de realizarse en el momento del análisis. Presentarlas así, permite tener en un cuadro una vista general y por tanto pensar en cómo controlarlas, para evitar en lo posible los sesgos.
DOI: 10.17632/hpkt3zxbkh
title: Complementary data: Pharmacological semen collection in giant anteaters (Myrmecophaga tridactyla): a feasible option for captive and free-living animals

description: Complementary data of the manuscript https://doi.org/10.1016/j.therwi.2023.100030
DOI: 10.17632/htsjmgkktb
title: FakeNewsSites

description: An exhaustive list of Fake News Sites publishing fake news online
DOI: 10.17632/kys36jgnb4
title: Sistematización del proceso de selección de documentos para RSL sobre responsabilidad social empresarial en la minería

description: La investigación se realixzó con la contribución relevante del equipo de investigacdores
DOI: 10.17632/m4mytxgc7z
title: TIS AsV 10 mM Raw data

description: TIS AsV 10 mM Raw data
DOI: 10.17632/ptjbbgxnsk
title: Age, obesity, sex hormone imbalance: Exploring factors associated with frontal baldness in male androgenetic alopecia patients: A cross-sectional study of 412 cases

description: Multiple linear regression for severity of frontal baldness (F score) including age, body mass index (BMI), serum triglyceride, serum testosterone as covariates was performed. Old age (adjusted β, 0.028; 95% CI, 0.022-0.035; p-value, <0.001) and higher BMI (adjusted β, 0.027; 95% CI, 0.000-0.055; p-value, 0.050) were found to be associated with more severe frontal baldness in male androgenetic alopecia patients.
DOI: 10.17632/ryxpgtwfkh
title: Gender and workplace social courage

description: Study 1 data include workplace social courage and organizational justice (distributive, process, and interactional justice). It also has descriptive statistics (gender, marital status, working duration, age, and education)
Study 2 data include workplace social courage, defensive silence and job performance variable. It also has descriptive statistics (gender, marital status, working duration, age, and education)
DOI: 10.17632/sdd2wcvbz8
title: Data for: Three-dimensional polarization ray tracing in electro-optic crystals

description: The data utilized in the paper "Three-dimensional polarization ray tracing in electro-optic crystals" should be open by Matlab. The files named as "dnA0", "dnA1", and "dnA2" are the data for Figure 4. The files named as "dnB0", "dnB1", and "dnB2" are the data for Figure 5. The files named as "Intensity0", "Intensity1", and "Intensity2" are the data for Figure 6.
DOI: 10.17632/ss6ghkd8bk
title: Inhibition of M1 polarization in alveolar macrophages by vasoactive intestinal peptide attenuates LPS-induced acute lung injury in vivo and vitro

description: Vasoactive intestinal peptide (VIP) is one of the neurotransmitters released by nonadrenergic noncholinergic inhibitory nerve endings. In lung tissues, VIP can inhibit alveolar macrophage phagocytosis and T lymphocyte proliferation, reduce the release of inflammatory mediators, and promote the repair of airway epithelial damage, thus playing an important role in treating pulmonary systemic diseases. This study aimed to explore the effects of VIP on lipopolysaccharide (LPS)-induced macrophage activation in vitro and LPS-induced acute lung injury (ALI) in mice. Mouse primary alveolar macrophage cells were treated with LPS (100 ng/mL) for 8 h and then co-incubated with different concentrations of VIP (108–106 mol/L) for 24 h. VIP treatment significantly inhibited LPS-induced alveolar macrophage M1 polarization and decreased the activation of the nuclear transcription factor-κB (NF-κB) signaling pathway. Subsequent studies confirmed that VIP-inhibited alveolar macrophage M1 polarization and NF-κB signaling pathway activation were dependent on the activation of Adenosine cyclic 3', 5'-monophosphate(cAMP)-protein kinase A(PKA)pathway. ALI was induced in mice by intraperitoneal (ip) injection of LPS (10 mg/kg), and different doses of VIP (1, 3, and 5 nmol/mouse, ip) were administered at 0, 8, and 16 h after LPS injection. VIP significantly reduced LPS-induced inflammatory cell infiltration, decreased the production of pro-inflammatory cytokines (TNF-α, IL-1β, and IL-6), and eliminated LPS-mediated pulmonary edema. Also, LPS-induced alveolar macrophage M1 polarization and NF-κB signaling pathway activation were inhibited. In conclusion, VIP could effectively reduce the LPS-induced inflammatory responses in vitro and in vivo; this beneficial effect was associated with the activation of cAMP-PKA pathway and the inhibition of NF-κB signaling pathway activation, thereby reducing the expression of pro-inflammatory mediators and cytokines. These data suggest that VIP may be a potential drug for the treatment of ALI.
DOI: 10.17632/v5fxzt2ms4
title: Data for: Pore-Scale Conjugate Heat Transfer Simulations Using Lattice Boltzmann Methods for Industrial Applications

description: The processed data and source code required to reproduce the findings presented in "Pore-Scale Conjugate Heat Transfer Simulations Using Lattice Boltzmann Methods for Industrial Applications" (https://doi.org/10.1016/j.applthermaleng.2020.116073) are available here.