cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.22002/ffgf2-0r036
title: Unspecified

description: Raw data files of Unspecified
description: <strong>Tilt Series Date:</strong> 2018-09-06</p>
<strong>Data Taken By:</strong> Jun Zhang</p>
<strong>Tilt Series Settings:</strong>  Single Axis, tilt range: (-54.0°, 54.0°), step: 2°, constant angular increment, dosage: 100.0 eV/Å²,  defocus: -7.0 μm,  magnification: 41000x. </p>
<strong>Acquisition Software:</strong> SerialEM</p>
<strong>Upload Method:</strong> pipeline</p>
<strong>Processing Software Used:</strong> Raptor</p>
description: Files available via S3 at https://sdsc.osn.xsede.org/ini210004tommorrell/tomography_archive/jza2018-09-06-112/rawdata/</p>JV9264_B40.mrc,  Tilt Series (Pixel Size 0.2654 nm), 1.5 GB  
        
<a role="button" class="ui compact mini button" href="https://sdsc.osn.xsede.org/ini210004tommorrell/tomography_archive/jza2018-09-06-112/rawdata/JV9264_B40.mrc"
        > <i class="download icon"></i> Download </a></p>

        JV9264_B40_full.rec,  Reconstruction (Pixel Size 1.0616 nm), 534.5 MB  
        
<a role="button" class="ui compact mini button" href="https://sdsc.osn.xsede.org/ini210004tommorrell/tomography_archive/jza2018-09-06-112/3dimage_98005/JV9264_B40_full.rec"
        > <i class="download icon"></i> Download </a></p>
DOI: 10.22002/5fpw5-enb82
title: Unspecified

description: Raw data files of Unspecified
description: <strong>Tilt Series Date:</strong> 2018-11-08</p>
<strong>Data Taken By:</strong> Georges Chreifi</p>
<strong>Tilt Series Settings:</strong>  Single Axis, tilt range: (-57.0°, 57.0°), step: 3°, constant angular increment, dosage: 100.0 eV/Å²,  defocus: -7.0 μm,  magnification: 27500x. </p>
<strong>Acquisition Software:</strong> SerialEM</p>
<strong>Upload Method:</strong> pipeline</p>
<strong>Processing Software Used:</strong> Raptor</p>
description: Files available via S3 at ttps://sdsc.osn.xsede.org/ini210004tommorrell/tomography_archive/gca2018-11-08-103/rawdata/</p>Fjoh4_70.mrc,  Tilt Series (Pixel Size 0.39 nm), 1.1 GB  
        
<a role="button" class="ui compact mini button" href="https://sdsc.osn.xsede.org/ini210004tommorrell/tomography_archive/gca2018-11-08-103/rawdata/Fjoh4_70.mrc"
        > <i class="download icon"></i> Download </a></p>

        Fjoh4_70_full.rec,  Reconstruction (Pixel Size 1.56 nm), 267.3 MB  
        
<a role="button" class="ui compact mini button" href="https://sdsc.osn.xsede.org/ini210004tommorrell/tomography_archive/gca2018-11-08-103/3dimage_98638/Fjoh4_70_full.rec"
        > <i class="download icon"></i> Download </a></p>
DOI: 10.22002/hvtyv-2g013
title: Unspecified

description: Raw data files of Unspecified
description: <strong>Tilt Series Date:</strong> 2018-11-08</p>
<strong>Data Taken By:</strong> Georges Chreifi</p>
<strong>Tilt Series Settings:</strong>  Single Axis, tilt range: (-57.0°, 57.0°), step: 3°, constant angular increment, dosage: 100.0 eV/Å²,  defocus: -7.0 μm,  magnification: 27500x. </p>
<strong>Acquisition Software:</strong> SerialEM</p>
<strong>Upload Method:</strong> pipeline</p>
<strong>Processing Software Used:</strong> Raptor</p>
description: Files available via S3 at ttps://sdsc.osn.xsede.org/ini210004tommorrell/tomography_archive/gca2018-11-08-94/rawdata/</p>Fjoh4_61.mrc,  Tilt Series (Pixel Size 0.39 nm), 996.2 MB  
        
<a role="button" class="ui compact mini button" href="https://sdsc.osn.xsede.org/ini210004tommorrell/tomography_archive/gca2018-11-08-94/rawdata/Fjoh4_61.mrc"
        > <i class="download icon"></i> Download </a></p>

        Fjoh4_61_full.rec,  Reconstruction (Pixel Size 1.56 nm), 267.3 MB  
        
<a role="button" class="ui compact mini button" href="https://sdsc.osn.xsede.org/ini210004tommorrell/tomography_archive/gca2018-11-08-94/3dimage_98614/Fjoh4_61_full.rec"
        > <i class="download icon"></i> Download </a></p>
DOI: 10.15468/dl.kq5ks9
title: Occurrence Download

description: A dataset containing 2303926052 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Kali tragus, Galium spurium, Callistemon citrinus, Lumbricus terrestris, Lytta vesicatoria, Reticulitermes lucifugus, Eriococcus spurius, Erannis defoliaria, Macrobrachium nipponense, Dendrolimus superans, Abbottina rivularis, Gamochaeta antillana, Soliva stolonifera, Tithonia tubaeformis, Varroa jacobsoni, Clarias macrocephalus, Animalia, Scurrula parasitica, Scurrula pulverulenta, Enteromius anoplus, Pupalia lappacea, Oplismenus hirtellus, Argemone subfusiformis, Crotalaria goreensis, Annona squamosa, Indigofera hirsuta, Distimake quinquefolius, Bispira polyomma, Cheiracanthium mildei, Mermessus denticulatus, Ostearius melanopygius, Pyemotes tritici, Phyllobius pilicornis, Otiorhynchus smreczynskii, Bythotrephes brevimanus, Cryptophilus obliteratus, Berginus tamarisci, Epuraea imperialis, Chymomyza amoena, Merodon caucasicus, Amphiareus obscuriceps, Rhagoletis cingulata, Aphis aurantii, Japananus hyalinus, Orientus ishidae, Pulvinaria floccifera, Pulvinaria hydrangeae, Nysius huttoni, Stephanitis takeyai, Tupiocoris rhododendri)",
 "BasisOfRecord is one of (Machine Observation, Human Observation, Observation)",
 "HasCoordinate is true",
 "Year is greater than or equal to 1990"
 ]
}

 The dataset includes 2303926052 records from 29932 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0032924-250811113504898/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.18150/8zodtb
title: Data for the publication titled: "Photocatalytic membranes based on Cu–NH2-MIL-125(Ti) protected by poly(vinylidene fluoride) for high and stable hydrogen production"

description: Research data that was used to create the publication entitled "Photocatalytic membranes based on Cu–NH2-MIL-125(Ti) protected by poly(vinylidene fluoride) for high and stable hydrogen production"All necessary information regarding equipment and methodology is available in the Readme files. The .zip files contain source files that can be opened using publicly available document and image processing programs (notes, Microsoft Word/Excel, Libre Office Calc, Photo Gallery).
DOI: 10.15468/dl.uxxevg
title: Occurrence Download

description: A dataset containing 36817 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasCoordinate is true",
 "TaxonKey is Streptomyces Waksman & Henrici, 1943"
 ]
}

 The dataset includes 36817 records from 429 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0006163-250525065834625/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.3535/rnf-4n8-53r
title: Sus scrofa Linnaeus, 1758

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/srz-jn1-anv
title: Pongo pygmaeus (Linnaeus, 1760)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/7hv-9sw-ag2
title: Cervidae Goldfuss, 1820

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/nba-k44-tet
title: Animalia

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/2ze-z6e-rs3
title: Bovidae Gray, 1821

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/d77-6vj-lm5
title: Animalia

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/xww-xcm-lya
title: Bovidae Gray, 1821

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/2ce-mt4-lnv
title: Animalia

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/81l-t0d-g7y
title: Plantae

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/0ps-atc-r6p
title: Animalia

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/xns-5f9-3cx
title: Plantae

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/jht-cac-k2l
title: Bubalus C. H. Smith, 1827

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/rvt-l0v-nww
title: Sus Linnaeus, 1758

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/7f5-e6b-y02
title: Cervus Linnaeus, 1758

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/8yj-xvf-ts4
title: Duboisia Szidat, 1936

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/wlm-0j4-99s
title: Chiroptera Blumenbach, 1779

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/ff5-4lb-0ge
title: Cervus Linnaeus, 1758

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/rve-aw6-5bj
title: Rhinoceros Linnaeus, 1758

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/aqb-p1j-gg5
title: Animalia

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/cwm-anf-pa8
title: Animalia

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/qyr-ph4-tdp
title: Bovidae Gray, 1821

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/m1f-sz7-pvk
title: Animalia

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/p5w-w4j-a8c
title: Bovidae Gray, 1821

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/a0r-h38-e7g
title: Animalia

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/l4x-rmx-rvs
title: Pongo pygmaeus (Linnaeus, 1760)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/vxq-gzz-zg7
title: Animalia

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/9rp-s44-b1f
title: Animalia

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/er6-d52-ha0
title: Sus Linnaeus, 1758

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.15468/dl.vh2ryw
title: Occurrence Download

description: A dataset containing 1881 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is one of (Human Observation, Specimen)",
 "Geometry POLYGON((-74.03194 41.87692,-72.42853 41.84541,-71.33508 45.03107,-73.55929 45.03633,-74.03194 41.87692))",
 "OccurrenceStatus is Present",
 "TaxonKey is Sarracenia purpurea"
 ]
}

 The dataset includes 1881 records from 21 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0023606-250811113504898/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.3535/g84-wj8-pw5
title: Proboscidea Illiger, 1811

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/gq6-lyx-vlg
title: Cervus Linnaeus, 1758

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/8qm-gec-wjm
title: Muntiacus muntjak (Zimmermann, 1780)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/l3x-d4x-s6k
title: Animalia

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/tc4-xqc-kyl
title: Pongo pygmaeus (Linnaeus, 1760)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/b6x-8ws-jyh
title: Cervus Linnaeus, 1758

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/vr1-d2h-5tf
title: Pongo pygmaeus (Linnaeus, 1760)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/h2j-7dd-d6g
title: Hippopotamus Linnaeus, 1758

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/s4s-g9l-r54
title: Paguma Gray, 1831

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/tcr-1zk-pfc
title: Bovidae Gray, 1821

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/tbl-jn4-kdc
title: Animalia

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.15468/dl.6z4vat
title: Occurrence Download

description: A dataset containing 171 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is China",
 "TaxonKey is Solidago canadensis"
 ]
}

 The dataset includes 171 records from 15 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0037358-251025141854904/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.30630134
title: Supplementary Materials for "Fetching IPEd" article

description: Supplementary Materials for "Fetching IPEd" article
DOI: 10.6084/m9.figshare.30630134.v1
title: Supplementary Materials for "Fetching IPEd" article

description: Supplementary Materials for "Fetching IPEd" article
DOI: 10.5281/zenodo.17063656
title: HAMSOM-VICE v0.9 input dataset, Bohai Sea 2011-2012

description: This dataset contains the input files for the HAMSOM-VICE sea ice simulation in the Bohai Sea from 2011 to 2012.

Forcing Data: AirT.direct, ClimateTS.direct, Cloudirect, EvPr.direct, RelH.direct, Wind.direct, WinS.direct, River.direct, Tide_ph02_8tides_116.dat (atmospheric forcing including air temperature, wind fields, humidity, cloud cover, evaporation-precipitation; oceanic forcing including river runoff and tidal parameters)

Initial Conditions: zeta.direct (initial sea surface height field)

Bathymetry Data: Topography10.dat (bathymetry topography), RiverIndices.dat (river indices)
DOI: 10.5281/zenodo.17063655
title: HAMSOM-VICE v0.9 input dataset, Bohai Sea 2011-2012

description: This dataset contains the input files for the HAMSOM-VICE sea ice simulation in the Bohai Sea from 2011 to 2012.

Forcing Data: AirT.direct, ClimateTS.direct, Cloudirect, EvPr.direct, RelH.direct, Wind.direct, WinS.direct, River.direct, Tide_ph02_8tides_116.dat (atmospheric forcing including air temperature, wind fields, humidity, cloud cover, evaporation-precipitation; oceanic forcing including river runoff and tidal parameters)

Initial Conditions: zeta.direct (initial sea surface height field)

Bathymetry Data: Topography10.dat (bathymetry topography), RiverIndices.dat (river indices)
DOI: 10.21227/jceb-0128
title: "The History of the Technical Implementation  of the 3D-Representation of the Digital Earth"

description: "A distinctive feature of the Digital Earth project is implementation a three-dimensional model of the Earth while simultaneously realizing such properties as multiscale and 3D-representation. The approaches that make it possible to realize the possibility of representing our planet from various angles are considered. The essence of the discrete global grid system method is outlined, as well as possible projection methods. A brief technical description of the method is provided with historical points of origin and descriptions. An effective way of working with data, preferred for the Digital Earth, is indexing, implemented using three methods \u2013 hierarchy, a curve filling the space and based on axes. Examples of the use of grid systems are given alongside the specifics of their application."
DOI: 10.15151/esrf-es-2232068254
title: CryoEM-BAG France: Structural biology using cryoEM in France

description: This proposal gathers Principal Investigators from Institutes across France that use cryoEM to unravel the molecular mechanisms associated with different
fundamental biological processes. Scientists belong to 12 centres that currently use CM01 for cryoEM. PIs in this application were part of the previous BAG
MX2596, with one new member who has previously used CM01 via rolling access, replacing two members who have left. For the next 6 month period we have asked for the same number of shifts as awarded for 2024/4 (48 shifts).
Over 18 projects from the BAG are ready for data collection at ESRF CM01. These include the study of bacterial and viral infection machineries (Bordeaux, Lyon,
Paris, Marseille), translational and trancriptional control mechanisms (Bordeaux, Toulouse, Paris, Strasbourg), structural proteins involved in muscle or macromolecular transport (Bordeaux, Lyon, Strasbourg, Paris), and enzymes (Paris, Bordeaux, Toulouse).
DOI: 10.15468/dl.nsqxdm
title: Occurrence Download

description: A dataset containing 80622 records in GBIF matching the query:
SELECT
 kingdom,
 kingdomkey,
 phylum,
 phylumkey,
 class,
 classkey,
 "order",
 orderkey,
 family,
 familykey,
 genus,
 genuskey,
 species,
 specieskey,
 "year",
 IF(ISNULL(kingdomkey), NULL, SUM(COUNT(*)) OVER (
 PARTITION BY kingdomkey, "year")) kingdomcount,
 IF(ISNULL(phylumkey), NULL, SUM(COUNT(*)) OVER (
 PARTITION BY phylumkey, "year")) phylumcount,
 IF(ISNULL(classkey), NULL, SUM(COUNT(*)) OVER (
 PARTITION BY classkey, "year")) classcount,
 IF(ISNULL(orderkey), NULL, SUM(COUNT(*)) OVER (
 PARTITION BY orderkey, "year")) ordercount,
 IF(ISNULL(familykey), NULL, SUM(COUNT(*)) OVER (
 PARTITION BY familykey, "year")) familycount,
 IF(ISNULL(genuskey), NULL, SUM(COUNT(*)) OVER (
 PARTITION BY genuskey, "year")) genuscount,
 COUNT(*) occurrences,
 MIN(GBIF_TEMPORALUNCERTAINTY(eventdate, eventtime)) mintemporaluncertainty,
 MIN(COALESCE(coordinateuncertaintyinmeters, 1000)) mincoordinateuncertaintyinmeters
FROM
 occurrence
WHERE
 occurrence.countrycode = 'CL'
 AND occurrence.occurrencestatus = 'PRESENT'
 AND (occurrence."year" &gt;= 2000 AND occurrence."year" &lt;= 2024)
 AND occurrence.hasgeospatialissues = FALSE
 AND NOT GBIF_STRINGARRAYCONTAINS(occurrence.issue, 'TAXON_MATCH_FUZZY', TRUE)
 AND (occurrence.distancefromcentroidinmeters &gt;= 2000.0 OR occurrence.distancefromcentroidinmeters IS NULL)
 AND NOT occurrence.basisofrecord IN ('FOSSIL_SPECIMEN', 'LIVING_SPECIMEN')
 AND (occurrence.specieskey IS NOT NULL AND occurrence."year" IS NOT NULL)
GROUP BY
 occurrence.kingdom,
 occurrence.kingdomkey,
 occurrence.phylum,
 occurrence.phylumkey,
 occurrence.class,
 occurrence.classkey,
 occurrence."order",
 occurrence.orderkey,
 occurrence.family,
 occurrence.familykey,
 occurrence.genus,
 occurrence.genuskey,
 occurrence.species,
 occurrence.specieskey,
 occurrence."year"

 The dataset's 80622 records were derived from 809 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0037357-251025141854904/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.29338655
title: KLF5 drives dichotomous lineage programs in pancreatic cancer via AAA+ ATPase coactivators - Bioluminesence_data_orthotopic_PDAC

description: Raw bioluminescence readings from orthotopic PDAC model
DOI: 10.6084/m9.figshare.29338655.v1
title: KLF5 drives dichotomous lineage programs in pancreatic cancer via AAA+ ATPase coactivators - Bioluminesence_data_orthotopic_PDAC

description: Raw bioluminescence readings from orthotopic PDAC model
DOI: 10.34740/kaggle/dsv/13751328
title: Financial and regulatory impact simulator
DOI: 10.15468/m2jwux
title: Miscellaneous taxonomic and nomenclatural notes on Microlicia D. Don (Melastomataceae)

description: This dataset contains the digitized treatments in Plazi based on the original journal article Romero, Rosana, Versiane, Ana Flávia Alves, Woodgyer, Elizabeth M. (2022): Miscellaneous taxonomic and nomenclatural notes on Microlicia D. Don (Melastomataceae). Phytotaxa 559 (2): 99-131, DOI: 10.11646/phytotaxa.559.2.1, URL: http://dx.doi.org/10.11646/phytotaxa.559.2.1
DOI: 10.34740/kaggle/dsv/13751393
title: Forex Exchange Rates Since 2004 (Updated Daily)
DOI: 10.5281/zenodo.17621498
title: Venetoclax and azacytidine in childhood primary advanced myelodysplastic syndromes, refractory/relapsed acute myeloid leukemia and therapy-related myeloid diseases
DOI: 10.5281/zenodo.17621499
title: Venetoclax and azacytidine in childhood primary advanced myelodysplastic syndromes, refractory/relapsed acute myeloid leukemia and therapy-related myeloid diseases
DOI: 10.6084/m9.figshare.30630131
title: Occurrence records and R code

description: Occurrence records and R code used to predict the global suitability areas of <i>Nilaparvata lugens</i> and<i> Sogatella furcifera</i>.
DOI: 10.6084/m9.figshare.30630131.v1
title: Occurrence records and R code

description: Occurrence records and R code used to predict the global suitability areas of <i>Nilaparvata lugens</i> and<i> Sogatella furcifera</i>.
DOI: 10.21227/08wq-j183
title: "Industrial Espionage is the Driving Force Behind Technical Progress in Radio Tube Technology"

description: "A study of vacuum tube technologies developed in France during World War I is conducted. The role of military intelligence and industrial espionage in the development of the French TM triode is noted. The designs of vacuum tube triodes by Henry Abraham, Michel P\u00e9ri and Jacques Biguet, Beauvais and the Junot detector triode are studied. The invention of the multivibrator by Abraham and Bloch is considered in detail. Abraham and Bloch's priority in the invention of the vacuum tube self-oscillating multivibrator circuit is shown."
DOI: 10.34740/kaggle/dsv/13751446
title: OBELiX
DOI: 10.5281/zenodo.17621456
title: LRP1 Gene Mutation Analysis in Developmental Dysplasia of the Hip

description: This dataset contains Sanger sequencing chromatograms and corresponding sequence files for exons 1-6 of the LRP1 (low density lipoprotein receptor-related protein 1) gene from two unrelated female patients diagnosed with developmental dysplasia of the hip (DDH). The data was generated as part of a mutation screening study to investigate potential genetic variants associated with DDH pathogenesis. Patient 1 (26-year-old female) and Patient 2 (17-year-old female) both presented with bilateral DDH and were treated with periacetabular osteotomy. Genomic DNA was extracted from peripheral blood samples, followed by PCR amplification using specific primers targeting each exon. PCR products were purified and subjected to bidirectional Sanger sequencing on an ABI 3730xl DNA Analyzer. Sequence analysis and variant calling were conducted using Chromas software and BLAST alignment against the human genome assembly GRCh38/hg38, with LRP1 gene located on chromosome 12q13.3. The dataset includes raw sequencing chromatograms in .ab1 format and consensus sequences in FASTA format, with Phred quality scores included in the chromatogram files. Sequence analysis revealed no pathogenic variants in the screened exons of the LRP1 gene in either patient, with all identified variants consistent with wild-type reference sequences or known benign polymorphisms. This study was approved by the Ethics Committee of the Fourth Medical Center of Chinese PLA General Hospital (approval number: 2023KY002-KS001), and written informed consent was obtained from both patients for genetic analysis and data sharing.