cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7111094
title: Three-year safety and two-year effectiveness of etanercept in patients with rheumatoid arthritis in Japan: Results of long-term postmarketing surveillance

description: <b>Objectives:</b> To evaluate the real-world safety and effectiveness of etanercept (ETN) in Japanese patients with rheumatoid arthritis. <b>Methods:</b> This postmarketing surveillance study (NCT00503139) assessed the safety and effectiveness of ETN treatment over 3 and 2 years (from June 2007 to September 2011), respectively. Safety was evaluated by occurrence and seriousness of adverse drug reactions (ADRs), and of adverse events (AEs) for malignancies. Effectiveness was assessed using the Disease Activity Score in 28 joints based on the erythrocyte sedimentation rate (ESR) with four variables (swollen and tender joint counts, ESR, and patient global assessment; DAS28-4/ESR). Treatment was considered effective if patients had a good/moderate response by the European League Against Rheumatism response criteria. <b>Results:</b> ADRs occurred in 256/675 (37.9%) patients, the most common being injection site reactions (4.4%) and nasopharyngitis (3.3%). Serious ADRs occurred in 60/675 (8.9%) patients, the most frequent being pneumonia (1.2%). The incident rate of malignancies (AEs) was 1.06 per 100 patient-years. Mean baseline DAS28-4/ESR for the 581 patients included in effectiveness analysis was 5.42, which decreased to 3.32 at 2 years. Eighty-two percent of patients achieved a moderate/good response at 2 years. <b>Conclusion:</b> Long-term ETN treatment safety and effectiveness were sustained over 3 and 2 years, respectively.
DOI: 10.6084/m9.figshare.7111094.v1
title: Three-year safety and two-year effectiveness of etanercept in patients with rheumatoid arthritis in Japan: Results of long-term postmarketing surveillance

description: <b>Objectives:</b> To evaluate the real-world safety and effectiveness of etanercept (ETN) in Japanese patients with rheumatoid arthritis. <b>Methods:</b> This postmarketing surveillance study (NCT00503139) assessed the safety and effectiveness of ETN treatment over 3 and 2 years (from June 2007 to September 2011), respectively. Safety was evaluated by occurrence and seriousness of adverse drug reactions (ADRs), and of adverse events (AEs) for malignancies. Effectiveness was assessed using the Disease Activity Score in 28 joints based on the erythrocyte sedimentation rate (ESR) with four variables (swollen and tender joint counts, ESR, and patient global assessment; DAS28-4/ESR). Treatment was considered effective if patients had a good/moderate response by the European League Against Rheumatism response criteria. <b>Results:</b> ADRs occurred in 256/675 (37.9%) patients, the most common being injection site reactions (4.4%) and nasopharyngitis (3.3%). Serious ADRs occurred in 60/675 (8.9%) patients, the most frequent being pneumonia (1.2%). The incident rate of malignancies (AEs) was 1.06 per 100 patient-years. Mean baseline DAS28-4/ESR for the 581 patients included in effectiveness analysis was 5.42, which decreased to 3.32 at 2 years. Eighty-two percent of patients achieved a moderate/good response at 2 years. <b>Conclusion:</b> Long-term ETN treatment safety and effectiveness were sustained over 3 and 2 years, respectively.
DOI: 10.6084/m9.figshare.7110839
title: Computer code and results from Use of daily Internet search query data improves real-time projections of influenza epidemics

description: All computer code necessary to reproduce our analysis can be found compressed as a .zip file. This code contains components of Wikipedia data [26] and NASA humidity data [41]. Re-use only permitted according to their policies.
DOI: 10.6084/m9.figshare.7110839.v1
title: Computer code and results from Use of daily Internet search query data improves real-time projections of influenza epidemics

description: All computer code necessary to reproduce our analysis can be found compressed as a .zip file. This code contains components of Wikipedia data [26] and NASA humidity data [41]. Re-use only permitted according to their policies.
DOI: 10.6084/m9.figshare.7110842
title: Electronic Supplementary Material - Data from A temporal shift in trophic diversity among a predator assemblage in a warming Arctic

description: Yurkowski-SupportingData-ESM
DOI: 10.6084/m9.figshare.7110836
title: Prediction results in FluChallenge format from Use of daily Internet search query data improves real-time projections of influenza epidemics

description: All forecasts (1–4 weeks) for all approaches (CDC ILI as baseline, Wikipedia without nowcast, Wikipedia- weekly, Wikipedia-daily) for all seasons can be found in the same format as the 2016/2017 Influenza Prediction Challenge and is compressed as a .zip file
DOI: 10.6084/m9.figshare.7110815
title: Koorneef Endocrinology CORT118335 Supplementary Materials

description: Supplementary Data to the article by Koorneef et al published in Endocrinology.
DOI: 10.6084/m9.figshare.7110752
title: Correlation of plasma microRNA-21 expression and bone turnover markers in postmenopausal women

description: <b>Objectives:</b> This study assessed the correlation of plasma microRNA-21 expression and bone turnover markers (BTMs: CTx, P1NP) in healthy Thai postmenopausal women. We secondarily compared microRNA-21 expression between participants with normal and low bone mineral density (BMD: osteopenia and osteoporosis). <b>Methods:</b> Postmenopausal women who had never been diagnosed with fracture or never used anti-osteoporosis drugs were included in this study. Baseline characteristics were collected from all 195 participants. BTMs and plasma miR-21-5p were analyzed from blood collection at 8:00 and 9:00 am after overnight fasting for at least 8 h. <b>Results:</b> There was no significant correlation between miR-21-5p and any of the BTMs (CTx, <i>r</i> = 0.094, <i>p</i> = 0.19; P1NP, <i>r</i> = 0.05, <i>p</i> = 0.485). Significant correlation between miR-21-5p and P1NP was found when participants were further categorized into those aged ≥70 years (<i>r</i> = 0.46, <i>p</i> = 0.05) and those having osteoporosis (<i>r</i> = 0.51, <i>p</i> = 0.06). Slight negative correlations were found between miR-21-5p and BMD. There was statistically significant higher expression of miR-21-5p in those with low BMD when compared to the normal BMD group (<i>p</i> <b>Conclusion:</b> In this study, we did not find significant correlation between plasma microRNA-21-5p expression and the BTMs. Nevertheless, there seemed to be higher expression of miR-21-5p in the low BMD participants.
DOI: 10.6084/m9.figshare.7110752.v1
title: Correlation of plasma microRNA-21 expression and bone turnover markers in postmenopausal women

description: <b>Objectives:</b> This study assessed the correlation of plasma microRNA-21 expression and bone turnover markers (BTMs: CTx, P1NP) in healthy Thai postmenopausal women. We secondarily compared microRNA-21 expression between participants with normal and low bone mineral density (BMD: osteopenia and osteoporosis). <b>Methods:</b> Postmenopausal women who had never been diagnosed with fracture or never used anti-osteoporosis drugs were included in this study. Baseline characteristics were collected from all 195 participants. BTMs and plasma miR-21-5p were analyzed from blood collection at 8:00 and 9:00 am after overnight fasting for at least 8 h. <b>Results:</b> There was no significant correlation between miR-21-5p and any of the BTMs (CTx, <i>r</i> = 0.094, <i>p</i> = 0.19; P1NP, <i>r</i> = 0.05, <i>p</i> = 0.485). Significant correlation between miR-21-5p and P1NP was found when participants were further categorized into those aged ≥70 years (<i>r</i> = 0.46, <i>p</i> = 0.05) and those having osteoporosis (<i>r</i> = 0.51, <i>p</i> = 0.06). Slight negative correlations were found between miR-21-5p and BMD. There was statistically significant higher expression of miR-21-5p in those with low BMD when compared to the normal BMD group (<i>p</i> <b>Conclusion:</b> In this study, we did not find significant correlation between plasma microRNA-21-5p expression and the BTMs. Nevertheless, there seemed to be higher expression of miR-21-5p in the low BMD participants.
DOI: 10.6084/m9.figshare.7110734
title: Song function and territoriality in male and female White-throated Dippers <i>Cinclus cinclus</i>

description: <b>Capsule:</b> Male White-throated Dippers <i>Cinclus cinclus</i> are more likely and quicker to respond to the playback of song than females, but both sexes are more likely to respond before the onset of breeding than after. <b>Aims:</b> Territoriality and the function of song in female birds have rarely been studied outside of the tropics or Australasia. We investigated territoriality and song function in males and females of a Northern temperate species, the White-throated Dipper. <b>Methods:</b> We conducted playback trials on established pairs and compared the responses of males and females according to the sex of the simulated intruder and the timing of playback relative to the onset of breeding. A response was classified as movement towards the speaker, singing or both. <b>Results:</b> Males were significantly more likely and quicker to respond to playback than females, but neither sex responded differently to the playback of male and female song. Both sexes were more likely to respond to playback before breeding had begun than after. <b>Conclusions:</b> Our results suggest that both males and females are territorial but that males take the dominant role in defence. Female song appears to elicit a similar response to male song and may play a role in territoriality or mate defence.
DOI: 10.6084/m9.figshare.7110734.v1
title: Song function and territoriality in male and female White-throated Dippers <i>Cinclus cinclus</i>

description: <b>Capsule:</b> Male White-throated Dippers <i>Cinclus cinclus</i> are more likely and quicker to respond to the playback of song than females, but both sexes are more likely to respond before the onset of breeding than after. <b>Aims:</b> Territoriality and the function of song in female birds have rarely been studied outside of the tropics or Australasia. We investigated territoriality and song function in males and females of a Northern temperate species, the White-throated Dipper. <b>Methods:</b> We conducted playback trials on established pairs and compared the responses of males and females according to the sex of the simulated intruder and the timing of playback relative to the onset of breeding. A response was classified as movement towards the speaker, singing or both. <b>Results:</b> Males were significantly more likely and quicker to respond to playback than females, but neither sex responded differently to the playback of male and female song. Both sexes were more likely to respond to playback before breeding had begun than after. <b>Conclusions:</b> Our results suggest that both males and females are territorial but that males take the dominant role in defence. Female song appears to elicit a similar response to male song and may play a role in territoriality or mate defence.
DOI: 10.6084/m9.figshare.7110668
title: Raw Data - Nedergaard et al. 2018 - The feasibility of predicting ground reaction forces during running from a trunk accelerometry driven mass-spring-damper model. PeerJ DOI: 10.7717/peerj.6105

description: Raw Dataset from 20 male subjects running at 2-5 m/s (a total of 320 trials) including:<i>- Measured Trunk Acc</i><i>- Modelled Upper Mass</i><i>- Measured GRF</i><i>- Predicted GRF</i><i>- Replicated GRF</i><br>Estimated MSD-model parameter from all 320 trial from a TrunkAcc-driven (ACCparam) and GRF-driven MSD-model (GRFparam)- ACCparam- GRFparam
DOI: 10.6084/m9.figshare.7110668.v1
title: Raw Data - Nedergaard et al. 2018 - The feasibility of predicting ground reaction forces during running from a trunk accelerometry driven mass-spring-damper model. PeerJ DOI: TBC

description: Raw Dataset from 20 male subjects running at 2-5 m/s (a total of 320 trials) including:<i>- Measured Trunk Acc</i><i>- Modelled Upper Mass</i><i>- Measured GRF</i><i>- Predicted GRF</i><i>- Replicated GRF</i><br>Estimated MSD-model parameter from all 320 trial from a TrunkAcc-driven (ACCparam) and GRF-driven MSD-model (GRFparam)- ACCparam- GRFparam
DOI: 10.17028/rd.lboro.7110647
title: Study 3 data

description: Dataset connected with article: 'Increasing the use of conceptually-derived strategies in arithmetic: using inversion problems to promote the use of associativity shortcuts.' Abstract: Conceptual knowledge of key principles underlying arithmetic is an important precursor to understanding algebra and later success in mathematics. One such principle is associativity, which allows individuals to solve problems in different ways by decomposing and recombining subexpressions (e.g. ‘a + b – c’ = ‘b – c + a’). More than any other principle, children and adults alike have difficulty understanding it, and educators have called for this to change. We report three intervention studies that were conducted in university classrooms to investigate whether adults’ use of associativity could be improved. In all three studies, it was found that those who first solved inversion problems (e.g. ‘a + b – b’) were more likely than controls to then use associativity on ‘a + b – c’ problems. We suggest that ‘a + b – b’ inversion problems may either direct spatial attention to the location of ‘b – c’ on associativity problems, or implicitly communicate the validity and efficiency of a right-to-left strategy. These findings may be helpful for those designing brief activities that aim to aid the understanding of arithmetic principles and algebra.
DOI: 10.17028/rd.lboro.7110644
title: Study 2 data

description: Dataset connected with article: 'Increasing the use of conceptually-derived strategies in arithmetic: using inversion problems to promote the use of associativity shortcuts.' Abstract: Conceptual knowledge of key principles underlying arithmetic is an important precursor to understanding algebra and later success in mathematics. One such principle is associativity, which allows individuals to solve problems in different ways by decomposing and recombining subexpressions (e.g. ‘a + b – c’ = ‘b – c + a’). More than any other principle, children and adults alike have difficulty understanding it, and educators have called for this to change. We report three intervention studies that were conducted in university classrooms to investigate whether adults’ use of associativity could be improved. In all three studies, it was found that those who first solved inversion problems (e.g. ‘a + b – b’) were more likely than controls to then use associativity on ‘a + b – c’ problems. We suggest that ‘a + b – b’ inversion problems may either direct spatial attention to the location of ‘b – c’ on associativity problems, or implicitly communicate the validity and efficiency of a right-to-left strategy. These findings may be helpful for those designing brief activities that aim to aid the understanding of arithmetic principles and algebra.
DOI: 10.17028/rd.lboro.7110647.v1
title: Study 3 data

description: Dataset connected with article: 'Increasing the use of conceptually-derived strategies in arithmetic: using inversion problems to promote the use of associativity shortcuts.' Abstract: Conceptual knowledge of key principles underlying arithmetic is an important precursor to understanding algebra and later success in mathematics. One such principle is associativity, which allows individuals to solve problems in different ways by decomposing and recombining subexpressions (e.g. ‘a + b – c’ = ‘b – c + a’). More than any other principle, children and adults alike have difficulty understanding it, and educators have called for this to change. We report three intervention studies that were conducted in university classrooms to investigate whether adults’ use of associativity could be improved. In all three studies, it was found that those who first solved inversion problems (e.g. ‘a + b – b’) were more likely than controls to then use associativity on ‘a + b – c’ problems. We suggest that ‘a + b – b’ inversion problems may either direct spatial attention to the location of ‘b – c’ on associativity problems, or implicitly communicate the validity and efficiency of a right-to-left strategy. These findings may be helpful for those designing brief activities that aim to aid the understanding of arithmetic principles and algebra.
DOI: 10.17028/rd.lboro.7110635
title: Study 1 data

description: Dataset connected with article: 'Increasing the use of conceptually-derived strategies in arithmetic: using inversion problems to promote the use of associativity shortcuts.' Abstract: Conceptual knowledge of key principles underlying arithmetic is an important precursor to understanding algebra and later success in mathematics. One such principle is associativity, which allows individuals to solve problems in different ways by decomposing and recombining subexpressions (e.g. ‘a + b – c’ = ‘b – c + a’). More than any other principle, children and adults alike have difficulty understanding it, and educators have called for this to change. We report three intervention studies that were conducted in university classrooms to investigate whether adults’ use of associativity could be improved. In all three studies, it was found that those who first solved inversion problems (e.g. ‘a + b – b’) were more likely than controls to then use associativity on ‘a + b – c’ problems. We suggest that ‘a + b – b’ inversion problems may either direct spatial attention to the location of ‘b – c’ on associativity problems, or implicitly communicate the validity and efficiency of a right-to-left strategy. These findings may be helpful for those designing brief activities that aim to aid the understanding of arithmetic principles and algebra.
DOI: 10.17028/rd.lboro.7110644.v1
title: Study 2 data

description: Dataset connected with article: 'Increasing the use of conceptually-derived strategies in arithmetic: using inversion problems to promote the use of associativity shortcuts.' Abstract: Conceptual knowledge of key principles underlying arithmetic is an important precursor to understanding algebra and later success in mathematics. One such principle is associativity, which allows individuals to solve problems in different ways by decomposing and recombining subexpressions (e.g. ‘a + b – c’ = ‘b – c + a’). More than any other principle, children and adults alike have difficulty understanding it, and educators have called for this to change. We report three intervention studies that were conducted in university classrooms to investigate whether adults’ use of associativity could be improved. In all three studies, it was found that those who first solved inversion problems (e.g. ‘a + b – b’) were more likely than controls to then use associativity on ‘a + b – c’ problems. We suggest that ‘a + b – b’ inversion problems may either direct spatial attention to the location of ‘b – c’ on associativity problems, or implicitly communicate the validity and efficiency of a right-to-left strategy. These findings may be helpful for those designing brief activities that aim to aid the understanding of arithmetic principles and algebra.
DOI: 10.6084/m9.figshare.7110605
title: lessismoredata.xlsx

description: Dataset of a manuscript "less is more activation"
DOI: 10.6084/m9.figshare.7110605.v2
title: lessismoredata.xlsx

description: Dataset of a manuscript "less is more activation"
DOI: 10.6084/m9.figshare.7110605.v1
title: data.xlsx

description: Dataset of a manuscript "less is more activation"
DOI: 10.6084/m9.figshare.7110425
title: Diel patterns of microphytobenthic primary production in intertidal sediments: the role of photoperiod on the vertical migration circadian rhythm

description: Diel primary production patterns of intertidal microphytobenthos (MPB) have been attributed to short-term physiological changes in the photosynthetic apparatus or to diel changes in the photoautrophic biomass in the sediment photic layer due to vertical migration. Diel changes in primary production and vertical migration are entrained by external factors like photoperiod and tides. However, the role of photoperiod and tides has not been experimentally separated to date. Here, we performed laboratory experiments with sediment cores kept in immersion, in the absence of tides, with photoperiod or under continuous light. Measurements of net production, made with O<sub>2</sub> microsensors, and of spectral reflectance at the sediment surface showed that, in intertidal sediments, the photoperiod signal can control diel patterns of net primary production and sediment oxygen availability through the vertical migration of the MPB photoautotrophic biomass. This vertical migration is controlled by an endogenous circadian rhythm exclusively entrained by photoperiod in the absence of tides, which in turn determines the diel oscillation in primary production. Fourier spectral analysis of temporal<sub> </sub>patterns confirmed that the photosynthetic circadian rhythm was mainly characterized by light/dark migratory cycles without any relevant contribution of the subjective <i>in situ </i>tidal period.
DOI: 10.6084/m9.figshare.7110401
title: Unsupervised software defect prediction sysmatic review meta-data synthesized from 49 selected papers

description: This dataset is extracted and synthesized from 49 primary studies which related to unsupervised defect prediction published between January 2000 and March 2018 and satisfied our inclusion criteria. It contains 2456 individual experimental results. We use this dataset to conduct a comparison study between supervised and unsupervised defect prediciton techniques.
DOI: 10.6084/m9.figshare.7110401.v1
title: Unsupervised software defect prediction sysmatic review meta-data synthesized from 47 selected papers (20181219)

description: This dataset is extracted and synthesized from 47 primary studies which related to unsupervised defect prediction published between January 2000 and March 2018 and satisfied our inclusion criteria. It contains 2326 individual experimental results. We use this dataset to conduct a comparison study between supervised and unsupervised defect prediciton techniques.
DOI: 10.6084/m9.figshare.7110401.v2
title: Unsupervised software defect prediction sysmatic review meta-data synthesized from 48 selected papers

description: This dataset is extracted and synthesized from 48 primary studies which related to unsupervised defect prediction published between January 2000 and March 2018 and satisfied our inclusion criteria. It contains 2348 individual experimental results. We use this dataset to conduct a comparison study between supervised and unsupervised defect prediciton techniques.
DOI: 10.6084/m9.figshare.7110401.v3
title: Unsupervised software defect prediction sysmatic review meta-data synthesized from 49 selected papers

description: This dataset is extracted and synthesized from 49 primary studies which related to unsupervised defect prediction published between January 2000 and March 2018 and satisfied our inclusion criteria. It contains 2456 individual experimental results. We use this dataset to conduct a comparison study between supervised and unsupervised defect prediciton techniques.
DOI: 10.6084/m9.figshare.7110365
title: Comparative Phylogenetic Data from Delayed trait development and the convergent evolution of shell kinesis in turtles

description: Trait data used in comparative phylogenetic analyses