cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q2g44snw
title: BindingDB Entry 8880: PDE9 inhibitors with imidazo triazinone backbone and imidazo pyrazinone backbone for treatment of peripheral diseases

description: Small molecule binding data for protein 3',5'-cyclic phosphodiesterase and Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B, Uniprot A0A024RB59, A0A0S2Z4T6, O76083, and Q01064
DOI: 10.7270/q26q20n0
title: BindingDB Entry 8882: Spirocyclic compounds

description: Small molecule binding data for protein Dual specificity mitogen-activated protein kinase kinase 1/Mitogen-activated protein kinase 1/RAF proto-oncogene serine/threonine-protein kinase and MAP kinase ERK1, Uniprot L7RXH5, P27361, P28482, and Q1HBJ4
DOI: 10.7270/q2kw5jdr
title: BindingDB Entry 8879: Imidazopyrazines and pyrazolopyrimidines and their use as AMPA receptor modulators

description: Small molecule binding data for protein Glutamate receptor AMPA 1/2, Uniprot P42261
DOI: 10.7270/q22z17zq
title: BindingDB Entry 8883: Bicyclic heterocyclic derivatives

description: Small molecule binding data for protein Pyruvate dehydrogenase kinase, Uniprot Q15119
DOI: 10.7270/q2tf00rd
title: BindingDB Entry 8885: JAK kinase inhibitor compounds for treatment of respiratory disease

description: Small molecule binding data for protein JAK1/TYK2, JAK3/JAK1, Non-receptor tyrosine-protein kinase TYK2, and Tyrosine-protein kinase JAK2, Uniprot A0A024R7E4, A0A024R7M7, O60674, P23458, P29597, and P52333
DOI: 10.7270/q2z60rgr
title: BindingDB Entry 8884: Compounds and pharmaceutical compositions thereof for the treatment of inflammatory disorders

description: Small molecule binding data for protein Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, Uniprot Q13822
DOI: 10.7270/q2pn981j
title: BindingDB Entry 8886: Fused heteroaryl derivatives as orexin receptor antagonists

description: Small molecule binding data for protein Orexin receptor type 1 and Orexin receptor type 2, Uniprot O43613, O43614, and S4X0W3
DOI: 10.7270/q2f47rjz
title: BindingDB Entry 8888: Organic compounds

description: Small molecule binding data for protein Homo sapiens phosphodiesterase 2A (PDE2A), Uniprot O00408
DOI: 10.7270/q2jw8h8c
title: BindingDB Entry 8887: Treatment and diagnosis of melanoma

description: Small molecule binding data for protein Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta, Uniprot F1D8N1, P55055, and Q13133
DOI: 10.7270/q29g5q6h
title: BindingDB Entry 8889: Inhibitor of lysine specific demethylase-1

description: Small molecule binding data for protein Lysine-specific histone demethylase 1A, Uniprot O60341
DOI: 10.7270/q21z46tb
title: BindingDB Entry 8891: Compounds and methods for inhibiting NHE-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders

description: Small molecule binding data for protein Sodium/hydrogen exchanger 3, Uniprot P26433
DOI: 10.7270/q25q4zh7
title: BindingDB Entry 8890: Macrocycle and composition comprising thereof

description: Small molecule binding data for protein ALK tyrosine kinase receptor and ALK tyrosine kinase receptor (L1196M), Uniprot D1MAM2 and Q9UM73
DOI: 10.7270/q2x63qbc
title: BindingDB Entry 8892: Treatment of relapsed and/or refractory solid tumors and non-hodgkin's lymphomas

description: Small molecule binding data for protein Lysine-specific histone demethylase 1A, Uniprot O60341
DOI: 10.7270/q2np26sz
title: BindingDB Entry 8894: Derivatives of sobetirome

description: Small molecule binding data for protein Thyroid hormone receptor apha and Thyroid hormone receptor beta, Uniprot A0A024R2I8, P10827, and P10828
DOI: 10.7270/q2sf2zjr
title: BindingDB Entry 8893: Beta-lactamase inhibitors, formulations, and uses thereof

description: Small molecule binding data for protein Beta-lactamase NDM-1, E3 ubiquitin-protein ligase ORTHRUS 5, and Ubiquitin-associated domain-containing protein 1, Uniprot A0A140VK64, C7C422, E9NWK5, Q680I0, and Q9BSL1
DOI: 10.7270/q2d79dsf
title: BindingDB Entry 8896: Compositions and methods for treating toxoplasmosis, cryptosporidiosis, and other apicomplexan protozoan related diseases

description: Small molecule binding data for protein Calmodulin-domain protein kinase 1, Calmodulin-domain protein kinase 1, putative, Calmodulin/Proto-oncogene tyrosine-protein kinase Src, Cereblon/BCR/ABL, and Tyrosine-protein kinase HCK, Uniprot A0A024R8E2, A3FQ16, P00519, P08631, P12931, and Q9BJF5
DOI: 10.7270/q2hx1g2n
title: BindingDB Entry 8895: 3-indol substituted derivatives, pharmaceutical compositions and methods for use

description: Small molecule binding data for protein Tryptophan 2,3-dioxygenase, Uniprot P48775
DOI: 10.7270/q28g8p3k
title: BindingDB Entry 8897: Certain chemical entities, compositions, and methods

description: Small molecule binding data for protein Tyrosine-protein kinase BTK, Uniprot Q06187
DOI: 10.7270/q20z75nh
title: BindingDB Entry 8899: Thiazolidinone compounds and use thereof

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 7, Uniprot P34969
DOI: 10.7270/q24q7xcv
title: BindingDB Entry 8898: Small molecule inhibitors of the nuclear translocation of androgen receptor for the treatment of castration-resistant prostate cancer

description: Small molecule binding data for protein Androgen receptor/Baculoviral IAP repeat-containing protein 2, Uniprot P10275
DOI: 10.7270/q2w66p43
title: BindingDB Entry 8900: 5-hydroxytryptamine receptor 7 activity modulators and their method of use

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 7, Uniprot P34969
DOI: 10.7270/q2rf5xcx
title: BindingDB Entry 8901: Biaryl kinase inhibitors

description: Small molecule binding data for protein AP2-associated protein kinase 1, Uniprot Q2M2I8
DOI: 10.7270/q2h134ds
title: BindingDB Entry 8903: Isoquinolin-3-yl carboxamides and preparation and use thereof

description: Small molecule binding data for protein Axin-1/Glycogen synthase kinase-3 beta, Dual-specificity tyrosine-phosphorylation regulated kinase 1A, and Proto-oncogene Wnt-1, Uniprot P04628, P49841, Q13627, and Q6FI27
DOI: 10.7270/q2mp55nk
title: BindingDB Entry 8902: Sulfonyl piperidine derivatives and their use for treating prokineticin mediated diseases

description: Small molecule binding data for protein Prokineticin receptor 1, Uniprot Q8TCW9
DOI: 10.7270/q2c82cqh
title: BindingDB Entry 8904: Metallo-beta-lactamase inhibitors

description: Small molecule binding data for protein Beta-lactamase, Beta-lactamase NDM-1, and Metallo-beta-lactamase type 2, Uniprot C7C422, E9NWK5, P52699, Q2QC95, and Q7DHD4
DOI: 10.7270/q23r0w8g
title: BindingDB Entry 8906: Heteroaryl substituted pyridyl compounds useful as kinase modulators

description: Small molecule binding data for protein Interleukin-1 receptor-associated kinase 4, Uniprot Q69FE3 and Q9NWZ3
DOI: 10.7270/q27h1n06
title: BindingDB Entry 8905: Isoindolinone inhibitors of the MDM2-p53 interaction having anticancer activity

description: Small molecule binding data for protein MDM2-MDMX, Uniprot Q00987
DOI: 10.7270/q20004gj
title: BindingDB Entry 8907: Modulators of sphingosine phosphate receptors

description: Small molecule binding data for protein Sphingosine 1-phosphate receptor and Sphingosine 1-phosphate receptor Edg-5/Sphingosine 1-phosphate receptor Edg-3, Uniprot P21453 and Q99500
DOI: 10.7270/q2qf8w80
title: BindingDB Entry 8909: 4-azaindole compounds

description: Small molecule binding data for protein Toll-like receptor 7, Toll-like receptor 8, and Toll-like receptor 9, Uniprot B2R9N9, Q9NR96, Q9NR97, and Q9NYK1
DOI: 10.7270/q2v69mzv
title: BindingDB Entry 8908: Derivatives and methods of treating hepatitis B infections

description: Small molecule binding data for protein Protein P, Uniprot Q9WRL0
DOI: 10.7270/q2ks6tx4
title: BindingDB Entry 8910: Bicyclic compounds and their use as antibacterial agents and β-lactamase inhibitors

description: Small molecule binding data for protein Bacterial beta-lactamase TEM, Beta-lactamase, and Carbapenem-hydrolyzing beta-lactamase KPC, Uniprot F8SM50, P62593, Q53TY8, Q6SJ61, and Q9L5C8
DOI: 10.7270/q2g1637z
title: BindingDB Entry 8911: Purine inhibitors of human phosphatidylinositol 3-kinase delta

description: Small molecule binding data for protein Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform/gamma isoform, Uniprot A0A2K8FKV1 and O00329
DOI: 10.7270/q26h4ksh
title: BindingDB Entry 8913: 5-HT2CR agonist analogs

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 2C, Uniprot P28335
DOI: 10.7270/q2z03bjr
title: BindingDB Entry 8915: Inhibitors of protein kinases

description: Small molecule binding data for protein JAK1, JAK3/JAK1, Tyrosine-protein kinase JAK2, and Tyrosine-protein kinase SYK, Uniprot A0A024R244, A0A024R7M7, O60674, P23458, P43405, and P52333
DOI: 10.7270/q22r3v1r
title: BindingDB Entry 8914: Tetrahydroisoquinolin-1-one derivative or salt thereof

description: Small molecule binding data for protein BRS3, Uniprot P32247
DOI: 10.7270/q2t72kvg
title: BindingDB Entry 8916: Substituted indole Mcl-1 inhibitors

description: Small molecule binding data for protein Apoptosis regulator Bcl-2/Bcl-2 homologous antagonist/killer, Bcl-2-like protein 1 (Bcl-xL), and MCL1-BAK1 complex, Uniprot A0A024R2B3, A0A0S2Z3C5, P10415, Q07817, and Q07820
DOI: 10.7270/q2pk0jh1
title: BindingDB Entry 8917: An Overview of Severe Acute Respiratory Syndrome-Coronavirus (SARS-CoV) 3CL Protease Inhibitors: Peptidomimetics and Small Molecule Chemotherapy.

description: Small molecule binding data for protein 3C-like proteinase (3CL-PRO), Papain-like protease (PLpro), and Replicase polyprotein 1ab, Uniprot A7J8L2, A7J8L3, P0C6U8, P0C6X1, and P0C6X7
DOI: 10.7270/q2f1923k
title: BindingDB Entry 8919: Acetyl-CoA carboxylase modulators

description: Small molecule binding data for protein Acetyl-CoA carboxylase, Uniprot Q3V4E6
DOI: 10.7270/q2js9st6
title: BindingDB Entry 8918: The recent outbreaks of human coronaviruses: A medicinal chemistry perspective.

description: Small molecule binding data for protein 3C-like proteinase, 3C-like proteinase (3CL-PRO), Angiotensin-converting enzyme 2, Cathepsin (L and K), Papain-like protease (PLpro), Replicase polyprotein 1ab, Spike glycoprotein, Spike glycoprotein S2 subunit, and Transmembrane protease serine 2, Uniprot A0A024R276, A0A1L2E0X0, A0A679G4D8,A0A6B9VP19, A7J8L2, A7J8L3, K9N5Q8, K9N7C7, O15393, P07711, P0C6U8, P0C6X1, P0C6X7, P0DTD1, P59594, Q202E9,A7J8L4, and Q9BYF1
DOI: 10.7270/q29889cv
title: BindingDB Entry 8920: Treatment of relapsed and/or refractory solid tumors and non-Hodgkin's lymphomas

description: Small molecule binding data for protein Lysine-specific histone demethylase 1A, Uniprot O60341
DOI: 10.7270/q21r6swz
title: BindingDB Entry 8922: Benzamide derivative

description: Small molecule binding data for protein Cytochrome P450 2C9 and p38 MAP kinase alpha/beta, Uniprot A0A024RD15, P11712, Q16539, and S5RV20
DOI: 10.7270/q25h7jmp
title: BindingDB Entry 8921: KSR antagonists

description: Small molecule binding data for protein Kinase suppressor of Ras 2, Uniprot Q6VAB6
DOI: 10.7270/q2x069ft
title: BindingDB Entry 8923: Acyl sulfonamide NaV1.7 inhibitors

description: Small molecule binding data for protein Sodium channel protein type 5 subunit alpha and Sodium channel protein type 9 subunit alpha, Uniprot Q14524 and Q15858
DOI: 10.7270/q2sb484t
title: BindingDB Entry 8924: Inhibitors of protease-activated receptor-2

description: Small molecule binding data for protein Proteinase-activated receptor 2, Uniprot P55085
DOI: 10.7270/q2ht2rr8
title: BindingDB Entry 8926: Quinolinone pyrimidines compositions as mutant-isocitrate dehydrogenase inhibitors

description: Small molecule binding data for protein IDH1 R132C and IDH1 R132H
DOI: 10.7270/q2nk3hfj
title: BindingDB Entry 8925: 1,4,5-substituted 1,2,3-triazole analogues as antagonists of the pregnane X receptor

description: Small molecule binding data for protein Nuclear receptor subfamily 1 group I member 2, Uniprot O75469
DOI: 10.7270/q2d2211n
title: BindingDB Entry 8927: 5-[3-[piperzin-1-yl]-3-oxo-propyl]-imidazolidine-2,4-dione derivatives as ADAMTS 4 and 5 inhibitors for treating E.G. osteoarthritis

description: Small molecule binding data for protein A disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAMTS-5), A disintegrin and metalloproteinase with thrombospondin motifs 6, ADAMTS5, Disintegrin and metalloproteinase domain-containing protein 17, Matrix metalloproteinase (1 and 13), and Matrix metalloproteinase 14, Uniprot B2RNB2, P45452, P50281, P78536, Q6TY19, Q9UKP5, and Q9UNA0
DOI: 10.7270/q24j0hjr
title: BindingDB Entry 8929: Methods using HDAC11 inhibitors

description: Small molecule binding data for protein Histone deacetylase 11, Uniprot Q96DB2
DOI: 10.7270/q289188g
title: BindingDB Entry 8928: Pyrimidine FGFR4 inhibitors

description: Small molecule binding data for protein Fibroblast growth factor receptor 1, Fibroblast growth factor receptor 2, Fibroblast growth factor receptor 3, and Fibroblast growth factor receptor 4, Uniprot P11362, P21802, P22455, and P22607
DOI: 10.7270/q20v8g59
title: BindingDB Entry 8930: Compounds as indoleamine 2,3-dioxygenase inhibitors

description: Small molecule binding data for protein Indoleamine 2,3-dioxygenase, Uniprot A0A348GSI3 and P14902
DOI: 10.7270/q2w37zqc
title: BindingDB Entry 8931: Substituted amino triazoles useful as human chitinase inhibitors

description: Small molecule binding data for protein Acidic mammalian chitinase (AMCase) and Chitinase 1, Uniprot Q13231 and Q9BZP6
DOI: 10.7270/q2rb771w
title: BindingDB Entry 8932: 4-(biphen-3-yl)-1H-pyrazolo[3,4-c]pyridazine derivatives of formula (I) as GABA receptor modulators for use in the treatment of epilepsy and pain

description: Small molecule binding data for protein Gamma-aminobutyric acid receptor subunit alpha-2/beta-2, Uniprot A0A024R9X6 and P47869
DOI: 10.7270/q2mk6g95
title: BindingDB Entry 8933: 5H-pyrrolo[2,3-D]pyrimidin-6(7H)-one derivative

description: Small molecule binding data for protein RAC-alpha serine/threonine-protein kinase AKT1, Ribosomal protein S6 kinase (P70S6K), and Ribosomal protein S6 kinase alpha 1, Uniprot B0LPE5, P31749, and Q15418
DOI: 10.7270/q2c24ztk
title: BindingDB Entry 8935: Quinolone derivatives as FGFR inhibitors

description: Small molecule binding data for protein Fibroblast growth factor receptor 1, Uniprot P11362
DOI: 10.7270/q2gt5qkf
title: BindingDB Entry 8934: 4,5-substituted picolinamide and picolinonitrile metabotropic glutamate receptor 2 negative allosteric modulators

description: Small molecule binding data for protein Metabotropic glutamate receptor 2, Uniprot P31421
DOI: 10.7270/q23n25rs
title: BindingDB Entry 8937: Benzenesulfonamide compounds, method for synthesizing same, and use thereof in medicine and cosmetics

description: Small molecule binding data for protein Disintegrin and metalloproteinase domain-containing protein 17 and Interstitial collagenase, Uniprot B2RNB2, P03956, and P78536
DOI: 10.7270/q279473n
title: BindingDB Entry 8936: Substituted pyrazolo[1,5-A]pyridine compounds as RET kinase inhibitors

description: Small molecule binding data for protein Proto-oncogene tyrosine-protein kinase receptor Ret (G810R), RET Kinase (V804M) (aa658-end), and RET Kinase (aa658-end)
DOI: 10.7270/q2zw1p9z
title: BindingDB Entry 8938: Isoquinolin-3-YL carboxamides and preparation and use thereof

description: Small molecule binding data for protein Axin-1/Glycogen synthase kinase-3 beta and Dual-specificity tyrosine-phosphorylation regulated kinase 1A, Uniprot P49841, Q13627, and Q6FI27
DOI: 10.7270/q2qc05x3
title: BindingDB Entry 8940: TrkA kinase inhibitors, compositions and methods thereof

description: Small molecule binding data for protein High affinity nerve growth factor receptor, Uniprot P04629
DOI: 10.7270/q2v40xm0
title: BindingDB Entry 8939: Piperazinyl methanone NAAA inhibitors

description: Small molecule binding data for protein N-acylethanolamine-hydrolyzing acid amidase , Uniprot Q02083
DOI: 10.7270/q2kk9f67
title: BindingDB Entry 8941: Glycosidase inhibitors

description: Small molecule binding data for protein N-acetyl-beta-D-glucosaminidase (O-GlcNAcase), Uniprot O60502
DOI: 10.7270/q26d5wdn
title: BindingDB Entry 8944: An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice.

description: Small molecule binding data for protein 3C-like proteinase and Replicase polyprotein 1ab, Uniprot A0A1L2E0X0, A0A679G4D8,A0A6B9VP19, and P0DTD1
DOI: 10.7270/q2b27xp6
title: BindingDB Entry 8943: Substituted isoxazolopyridazinones and isothiazolopyridazinones and methods of use

description: Small molecule binding data for protein GABA-B receptor, Uniprot H9NIL8 and O75899
DOI: 10.7270/q2ft8pdm
title: BindingDB Entry 8942: Substituted imidazo[1,2-a]pyrazines as LSD1 inhibitors

description: Small molecule binding data for protein Lysine-specific histone demethylase 1A, Uniprot O60341
DOI: 10.7270/q22n54qr
title: BindingDB Entry 8945: Identification of Antiviral Drug Candidates against SARS-CoV-2 from FDA-Approved Drugs.

description: Small molecule binding data for protein Replicase polyprotein 1ab, Uniprot A0A679G4D8,A0A6B9VP19 and P0DTD1
DOI: 10.7270/q2t43wh2
title: BindingDB Entry 8947: Tetrahydroisoquinolines as PRMT5 inhibitors

description: Small molecule binding data for protein Protein arginine N-methyltransferase 5, Uniprot O14744
DOI: 10.7270/q2xw4n7g
title: BindingDB Entry 8946: NK-3 receptor selective antagonist compounds, pharmaceutical composition and methods for use in NK-3 receptors mediated disorders

description: Small molecule binding data for protein Neurokinin 3 receptor, Uniprot P29371
DOI: 10.7270/q2pc34sq
title: BindingDB Entry 8948: Indane and indoline derivatives and the use thereof as soluble guanylate cyclase activators

description: Small molecule binding data for protein Soluble Guanylate Cyclases, Uniprot Q02108 and Q02153
DOI: 10.7270/q2dv1n97
title: BindingDB Entry 8950: Kinase inhibitors and their use in cancer therapy

description: Small molecule binding data for protein RAC-alpha serine/threonine-protein kinase AKT1 and RAC-alpha serine/threonine-protein kinase AKT1 (E17K), Uniprot B0LPE5 and P31749
DOI: 10.7270/q2jm2d1z
title: BindingDB Entry 8949: Pyridazinones as PARP7 inhibitors

description: Small molecule binding data for protein Protein mono-ADP-ribosyltransferase TIPARP, Uniprot Q7Z3E1
DOI: 10.7270/q25d8v88
title: BindingDB Entry 8952: JAK inhibitors containing a 4-membered heterocyclic amide

description: Small molecule binding data for protein JAK1/TYK2, JAK3/JAK1, Non-receptor tyrosine-protein kinase TYK2, and Tyrosine-protein kinase JAK2, Uniprot A0A024R7E4, A0A024R7M7, O60674, P23458, P29597, and P52333
DOI: 10.7270/q2959kz4
title: BindingDB Entry 8951: 2-azabicyclo[3.1.0]hexan-3-one derivatives and methods of use

description: Small molecule binding data for protein Mitogen-activated protein kinase kinase kinase 14, Uniprot Q99558
DOI: 10.7270/q21n83jx
title: BindingDB Entry 8953: Prodrugs of imidazotriazine compounds as CK2 inhibitors

description: Small molecule binding data for protein Casein kinase II subunit alpha and Casein kinase II subunit alpha', Uniprot P19784 and P68400
DOI: 10.7270/q2ww7m33
title: BindingDB Entry 8954: Indanylaminoazadihydrobenzofuranylacetic acids, pharmaceutical compositions for the treatment of diabetes

description: Small molecule binding data for protein Free fatty acid receptor 1, Uniprot O14842
DOI: 10.7270/q2nc63kf
title: BindingDB Entry 8956: Spiro[3H-indole-3,2′-pyrrolidin]-2(1H)-one compounds and derivatives as MDM2-P53 inhibitors

description: Small molecule binding data for protein MDM2-MDMX (aa 23-127)
DOI: 10.7270/q2s46vcp
title: BindingDB Entry 8955: Ether compounds for treatment of complement mediated disorders

description: Small molecule binding data for protein Complement factor D, Uniprot P00746
DOI: 10.7270/q2hm5bvq
title: BindingDB Entry 8957: Fused tricyclic compounds as Raf kinase inhibitors

description: Small molecule binding data for protein B-RAF V600E and C-Raf (Y340D/Y341D)
DOI: 10.7270/q2862jvr
title: BindingDB Entry 8959: Meta-azacyclic amino benzoic acid derivatives as pan integrin antagonists

description: Small molecule binding data for protein ITGAV/ITGB3, ITGAV/ITGB5, ITGAV/ITGB8, Integrin alpha5beta1, Integrin alpha5beta6, Integrin alpha8beta1, and Integrin alphavbeta1, Uniprot L7RT22, L7RXH0, P05106, P06756, P08648, P18084, P18564, P26012, and P53708
DOI: 10.7270/q2cz39jq
title: BindingDB Entry 8958: Sodium channel modulators

description: Small molecule binding data for protein Sodium channel protein type 2 alpha subunit and Sodium channel protein type 8 subunit alpha, Uniprot Q99250 and Q9UQD0
DOI: 10.7270/q24f1t4f
title: BindingDB Entry 8960: Morpholine and 1,4-oxazepane amides as somatostatin receptor subtype 4 (SSTR4) agonists

description: Small molecule binding data for protein Somatostatin receptor type 1, Somatostatin receptor type 2, Somatostatin receptor type 3, Somatostatin receptor type 4, and Somatostatin receptor type 5, Uniprot P30872, P30874, P31391, P32745, and P35346
DOI: 10.7270/q20p12d3
title: BindingDB Entry 8961: Cot modulators and methods of use thereof

description: Small molecule binding data for protein MER intracellular domain/EGFR extracellular domain chimera, Uniprot P00533
DOI: 10.7270/q2vx0jwz
title: BindingDB Entry 8962: 5-(n-[6,5]-fused bicyclic aryl tetrahydroisoquinolin-6-yl) pyridin-3-yl acetic acid derivatives as inhibitors of human immunodeficiency virus replication

description: Small molecule binding data for protein Envelope glycoprotein gp160, Uniprot Q72502
DOI: 10.7270/q2r49t4z
title: BindingDB Entry 8963: Bis-pyridazine compounds and their use in treating cancer

description: Small molecule binding data for protein Glutaminase kidney isoform, mitochondrial, Uniprot O94925
DOI: 10.7270/q2gq715h
title: BindingDB Entry 8965: Dopamine D3 receptor antagonists having a morpholine moiety

description: Small molecule binding data for protein D(3) dopamine receptor and d2, Uniprot A0A024R3C5, P14416, and P35462
DOI: 10.7270/q2mc92dm
title: BindingDB Entry 8964: Arylamide derivatives having multimodal activity against pain

description: Small molecule binding data for protein Mu-type opioid receptor and Voltage-dependent calcium channel subunit alpha-2/delta-1, Uniprot P35372 and P54289
DOI: 10.5281/zenodo.1004109
title: Cf263 Egl-20(Mu39)Iv | 2010-07-13T15:34:15+01:00

description: This experiment is part of the <em>C.elegans behavioural database</em>. For more information and the complete collection of experiments visit http://movement.openworm.org



<b>preview link</b> : https://www.youtube.com/watch?v=3yn4uJ6oQ8c
<b>strain</b> : CF263
<b>timestamp</b> : 2010-07-13T15:34:15+01:00
<b>gene</b> : egl-20
<b>chromosome</b> : IV
<b>allele</b> : mu39
<b>strain_description</b> : egl-20(mu39)IV
<b>sex</b> : hermaphrodite
<b>stage</b> : adult
<b>ventral_side</b> : clockwise
<b>media</b> : NGM agar low peptone
<b>arena</b> :   
  <b>style</b> : petri
  <b>size</b> : 35
  <b>orientation</b> : away
  

<b>food</b> : OP50
<b>habituation</b> : 30m wait
<b>who</b> : Laura Grundy
<b>protocol</b> : Method in E. Yemini et al. doi:10.1038/nmeth.2560. Worm transferred to arena 30 minutes before recording starts.
<b>lab</b> :   
  <b>name</b> : William R Schafer
  <b>location</b> : MRC Laboratory of Molecular Biology, Hills Road, Cambridge, CB2 0QH, UK
  

<b>software</b> :   
  <b>name</b> : tierpsy (https://github.com/ver228/tierpsy-tracker)
  <b>version</b> : cbfc23eb4f1ac2f29be75ade7a937eed58a5b219
  <b>featureID</b> : @OMG
  

<b>base_name</b> : egl-20 (mu39)IV on food L_2010_07_13__15_34_15___6___13
<b>total time (s)</b> : 899.524
<b>frames per second</b> : 25.7069
<b>video micrometers per pixel</b> : 4.45817
<b>number of segmented skeletons</b> : 19045