cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q2h133km
title: BindingDB Entry 50044528: Discovery of antitubulin agents with antiangiogenic activity as single entities with multitarget chemotherapy potential.

description: Small molecule binding data for protein Vascular endothelial growth factor receptor 2, Uniprot P35968
DOI: 10.7270/q2hd7xc5
title: BindingDB Entry 50046016: Mitigation of Acetylcholine Esterase Activity in the 1,7-Diazacarbazole Series of Inhibitors of Checkpoint Kinase 1.

description: Small molecule binding data for protein Acetylcholinesterase and Serine/threonine-protein kinase Chk1, Uniprot O14757 and P22303
DOI: 10.7270/q2hx1fbt
title: BindingDB Entry 50045505: Identification and optimization of pyridazinones as potent and selective c-Met kinase inhibitors.

description: Small molecule binding data for protein Hepatocyte growth factor receptor and Phosphodiesterase 4, Uniprot P08581, P27815, Q07343, Q08493, and Q08499
DOI: 10.7270/q2js9rwp
title: BindingDB Entry 50043378: Development of new deoxycytidine kinase inhibitors and noninvasive in vivo evaluation using positron emission tomography.

description: Small molecule binding data for protein Deoxycytidine kinase, Uniprot P27707 and P43346
DOI: 10.7270/q2mc91j0
title: BindingDB Entry 50044022: Discovery of orally bioavailable NK1 receptor antagonists.

description: Small molecule binding data for protein Neurokinin 1 receptor, Uniprot P25103
DOI: 10.7270/q2ms3vb3
title: BindingDB Entry 50044527: Discovery of PF-5190457, a Potent, Selective, and Orally Bioavailable Ghrelin Receptor Inverse Agonist Clinical Candidate.

description: Small molecule binding data for protein Ghrelin receptor, Serotonin receptor (2b and 2c), and Voltage-gated potassium channel, Uniprot P41595, Q12809, and Q92847
DOI: 10.7270/q2np262j
title: BindingDB Entry 50045504: Design, synthesis and preliminary biological evaluation of C-8 substituted guanine derivatives as small molecular inhibitors of FGFRs.

description: Small molecule binding data for protein Fibroblast growth factor receptor 1, Fibroblast growth factor receptor 2, Fibroblast growth factor receptor 3, and Fibroblast growth factor receptor 4, Uniprot P11362, P21802, P22455, and P22607
DOI: 10.7270/q2rj4m2t
title: BindingDB Entry 50044526: Fused Thiazin-3-ones as KCa3.1 Inhibitors.

description: Small molecule binding data for protein Intermediate conductance calcium-activated potassium channel protein 4, Uniprot O15554
DOI: 10.7270/q2sf2xtx
title: BindingDB Entry 50045503: Stereoselective synthesis, biological evaluation, and modeling of novel bile acid-derived G-protein coupled bile acid receptor 1 (GP-BAR1, TGR5) agonists.

description: Small molecule binding data for protein G-protein coupled bile acid receptor 1, Uniprot Q8TDU6
DOI: 10.7270/q2vm4dzm
title: BindingDB Entry 50046021: Discovery of Quinazoline-Based Fluorescent Probes toa1-Adrenergic Receptors.

description: Small molecule binding data for protein Adrenergic alpha1B, Alpha-1A adrenergic receptor, and Alpha-1D adrenergic receptor, Uniprot P25100, P35348, and P35368
DOI: 10.7270/q2vx0j1r
title: BindingDB Entry 50044020: TBA

description: Small molecule binding data for protein Human immunodeficiency virus type 1 reverse transcriptase
DOI: 10.7270/q2w95brp
title: BindingDB Entry 50044525: Treatment of Immunological or Inflammatory Disorders with ITK Kinase Inhibitors.

description: Small molecule binding data for protein Tyrosine-protein kinase ITK/TSK, Uniprot Q08881
DOI: 10.7270/q2wh2rms
title: BindingDB Entry 50045059: Distinct binding mode of multikinase inhibitor lenvatinib revealed by biochemical characterization.

description: Small molecule binding data for protein Vascular endothelial growth factor receptor 2, Uniprot P35968
DOI: 10.7270/q2x068gv
title: BindingDB Entry 50043383: Identification and optimization of pteridinone Toll-like receptor 7 (TLR7) agonists for the oral treatment of viral hepatitis.

description: Small molecule binding data for protein Toll-like receptor 8 (TLR8), Uniprot Q9NR97
DOI: 10.7270/q20z74z4
title: BindingDB Entry 50045509: Loratadine analogues as MAGL inhibitors.

description: Small molecule binding data for protein Fatty-acid amide hydrolase 1 (FAAH), Monoacylglycerol lipase ABHD12, Monoacylglycerol lipase ABHD6, and Monoglyceride Lipase (MGL), Uniprot O00519, Q8N2K0, Q99685, and Q9BV23
DOI: 10.7270/q2348n35
title: BindingDB Entry 50046027: Synthesis and Initial in Vivo Studies with [(11)C]SB-216763: The First Radiolabeled Brain Penetrative Inhibitor of GSK-3.

description: Small molecule binding data for protein Glycogen synthase kinase-3, Uniprot P49840
DOI: 10.7270/q23b61n6
title: BindingDB Entry 50044026: Chiral DNA gyrase inhibitors. 3. Probing the chiral preference of the active site of DNA gyrase. Synthesis of 10-fluoro-6-methyl-6,7-dihydro-9-piperazinyl- 2H-benzo[a]quinolizin-20-one-3-carboxylic acid analogues.

description: Small molecule binding data for protein DNA Gyrase, Uniprot P0AES4 and P0AES6
DOI: 10.7270/q23r0vf9
title: BindingDB Entry 50044531: 2-(2-Arylphenyl)benzoxazole As a Novel Anti-Inflammatory Scaffold: Synthesis and Biological Evaluation.

description: Small molecule binding data for protein Cyclooxygenase and Prostaglandin G/H synthase (cyclooxygenase), Uniprot P05979 and P35354
DOI: 10.7270/q26w9ct5
title: BindingDB Entry 50046026: N-(3-Ethynyl-2,4-difluorophenyl)sulfonamide Derivatives as Selective Raf Inhibitors.

description: Small molecule binding data for protein RAF serine/threonine protein kinase, Uniprot P15056
DOI: 10.7270/q2736sd0
title: BindingDB Entry 50044025: A three-dimensional pharmacophore model for 5-hydroxytryptamine6 (5-HT6) receptor antagonists.

description: Small molecule binding data for protein 5-Hydroxytryptamine receptor 6 (5-HT6), Uniprot P50406
DOI: 10.7270/q27h1m4k
title: BindingDB Entry 50044530: Novel carboline derivatives as potent antifungal lead compounds: design, synthesis, and biological evaluation.

description: Small molecule binding data for protein Cytochrome P450 2C19, Cytochrome P450 2C9, and Cytochrome P450 3A, Uniprot P08684, P11712, and P33261
DOI: 10.7270/q29w0h0k
title: BindingDB Entry 50044032: Discovery of uracil-based histone deacetylase inhibitors able to reduce acquired antifungal resistance and trailing growth in Candida albicans.

description: Small molecule binding data for protein Histone deacetylase 1, Histone deacetylase 4, Histone deacetylase HD1B, and Histone deacetylase HD2, Uniprot O09106, P56524, and Q94F81
DOI: 10.7270/q2bp04jf
title: BindingDB Entry 50046025: Discovery of a Potent Class of PI3Ka Inhibitors with Unique Binding Mode via Encoded Library Technology (ELT).

description: Small molecule binding data for protein PI3-kinase subunit alpha, PI3-kinase subunit beta, PI3-kinase subunit delta, and PI3-kinase subunit gamma, Uniprot O00329, P42336, P42338, and P48736
DOI: 10.7270/q2h133pz
title: BindingDB Entry 50045513: The discovery of potent agonists for GPR88, an orphan GPCR, for the potential treatment of CNS disorders.

description: Small molecule binding data for protein Probable G-protein coupled receptor 88, Uniprot Q9GZN0
DOI: 10.7270/q2ht2qrv
title: BindingDB Entry 50043386: Design, synthesis, and characterization of novel tetrahydropyran-based bacterial topoisomerase inhibitors with potent anti-gram-positive activity.

description: Small molecule binding data for protein DNA Gyrase and Topoisomerase IV, Uniprot P0A0K8, P0C1U9, P20831, and Q2FYS5
DOI: 10.7270/q2kd20d5
title: BindingDB Entry 50044030: Biarylaniline phenethanolamines as potent and selective beta3 adrenergic receptor agonists.

description: Small molecule binding data for protein Beta-1 adrenergic receptor, Beta-2 adrenergic receptor and beta-3 adrenergic receptor, and Beta-3 adrenergic receptor, Uniprot P07550, P08588, and P13945
DOI: 10.7270/q2ks6t3c
title: BindingDB Entry 50044535: Development of novel benzomorpholine class of diacylglycerol acyltransferase I inhibitors.

description: Small molecule binding data for protein Acyl Cholesterol Acyltransferase 1 (ACAT-1), Acyl-coenzyme A:cholesterol acyltransferase 2 (ACAT2), Cannabinoid receptor 1, Caspase-8, Caspase-9, Cytochrome P450 2C9, Diacylglycerol O-acyltransferase 1, Diacylglycerol O-acyltransferase 1 (DGAT1), Diacylglycerol O-acyltransferase 2, Dopamine receptor D2L/neurotensin receptor NTS1, Epidermal growth factor receptor, Insulin receptor, and Prostanoid IP receptor, Uniprot O75907, O75908, P00533, P06213, P11712, P14416, P21554, P35610, P43119, P55211, Q14790, Q96PD7, and Q9Z2A7
DOI: 10.7270/q2m61n0h
title: BindingDB Entry 50046023: Discovery of MK-1421, a Potent, Selective sstr3 Antagonist, as a Development Candidate for Type 2 Diabetes.

description: Small molecule binding data for protein Calcium channel (Type L), Cytochrome P450 2C8, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), Cytochrome P450 3A, Neurokinin 2 receptor, Phosphodiesterase 4, Pregnane X receptor (PXR), Somatostatin receptor, Somatostatin receptor 1, Somatostatin receptor 3, Somatostatin receptor 4, Somatostatin receptor 5, Somatostatin receptor subtype 3, Voltage-gated potassium channel, and Voltage-gated sodium channel subunit Nav1.5, Uniprot O75469, P08684, P10632, P10635, P11712, P21452, P27815, P30872, P30874, P30935, P30936, P31391, P32745, P35346, Q07343, Q08493, Q08499, Q12809, Q13936, and Q14524
DOI: 10.7270/q2mp54z6
title: BindingDB Entry 50045512: 8-(3-chloro-4-methoxybenzyl)-8H-pyrido[2,3-d]pyrimidin-7-one derivatives as potent and selective phosphodiesterase 5 inhibitors.

description: Small molecule binding data for protein cGMP-specific 3',5'-cyclic phosphodiesterase, Uniprot O77746
DOI: 10.7270/q2nk3ggk
title: BindingDB Entry 50043385: Anti-inflammatory effects of extracellular cyclosporins are exclusively mediated by CD147.

description: Small molecule binding data for protein Cyclophilin A, Cyclophilin B (CypB), and Cyclophilin C (CypC), Uniprot P23284, P45877, and P62937
DOI: 10.7270/q2q52r4h
title: BindingDB Entry 50044029: Structural basis of inhibitor specificity of the human protooncogene proviral insertion site in moloney murine leukemia virus (PIM-1) kinase.

description: Small molecule binding data for protein Serine/threonine-protein kinase PIM, Uniprot P11309
DOI: 10.7270/q2qv3p79
title: BindingDB Entry 50046022: Design, Synthesis, and Biological Evaluation of Novel Imidazo[1,2-a]pyridine Derivatives as Potent c-Met Inhibitors.

description: Small molecule binding data for protein AXL receptor tyrosine kinase, Hepatocyte growth factor receptor, Proto-oncogene tyrosine-protein kinase MER, Tyrosine-protein kinase receptor TYRO3, and Voltage-gated potassium channel, Uniprot P08581, P30530, Q06418, Q12809, and Q12866
DOI: 10.7270/q2rr20v0
title: BindingDB Entry 50045060: Synthesis and Structure-Activity Relationship Study of 5a-Carbasugar Analogues of SL0101.

description: Small molecule binding data for protein Ribosomal protein S6 kinase alpha 3, Uniprot P51812
DOI: 10.7270/q2sb475v
title: BindingDB Entry 50043384: Identification of the KDM2/7 histone lysine demethylase subfamily inhibitor and its antiproliferative activity.

description: Small molecule binding data for protein Histone demethylase JARID1A, Lysine-specific demethylase 2A, Lysine-specific demethylase 4A (KDM4A), Lysine-specific demethylase 4C (KDM4C), and Lysine-specific demethylase 6A (KDM6A), Uniprot I3VM53, O15550, O75164, P29375, Q9H3R0, and Q9Y2K7
DOI: 10.7270/q2tx3gwz
title: BindingDB Entry 50044028: 2,5-diketopiperazines as potent, selective, and orally bioavailable oxytocin antagonists. 2. Synthesis, chirality, and pharmacokinetics.

description: Small molecule binding data for protein Oxytocin receptor, Vasopressin V1a receptor (V1a), Vasopressin V1b receptor, and Vasopressin V2 receptor (V2), Uniprot P30518, P30559, P37288, and P47901
DOI: 10.7270/q2w66nfq
title: BindingDB Entry 50045510: Synthesis of 6-aryl-substituted sulfocoumarins and investigation of their carbonic anhydrase inhibitory action.

description: Small molecule binding data for protein Carbonic anhydrase, Carbonic anhydrase 12, Carbonic anhydrase 2, and Carbonic anhydrase 9, Uniprot O43570, P00915, P00918, and Q16790
DOI: 10.7270/q2zp47mp
title: BindingDB Entry 50044027: 3D-QSAR comparative molecular field analysis on opioid receptor antagonists: pooling data from different studies.

description: Small molecule binding data for protein Nociceptin/mu opioid receptor, Opioid receptors; mu & delta, and mu/kappa opioid receptor, Uniprot P33533, P33535, and P41144
DOI: 10.7270/q2028t3m
title: BindingDB Entry 50044532: Optimization of GPR40 Agonists for Type 2 Diabetes.

description: Small molecule binding data for protein Free fatty acid receptor 1, Uniprot O14842
DOI: 10.7270/q20r9qvh
title: BindingDB Entry 50043390: Investigation of an F-18 oxytocin receptor selective ligand via PET imaging.

description: Small molecule binding data for protein Oxytocin receptor, Uniprot P30559
DOI: 10.7270/q22f7pxr
title: BindingDB Entry 50044034: alpha,alpha-Cyclic aminoacids as useful scaffolds for the preparation of hNK(2) receptor antagonists.

description: Small molecule binding data for protein Neurokinin 2 receptor, Uniprot P21452 and Q64077
DOI: 10.7270/q22v2hps
title: BindingDB Entry 50044539: Chlorpheniramine Analogues Reverse Chloroquine Resistance in Plasmodium falciparum by Inhibiting PfCRT.

description: Small molecule binding data for protein Chloroquine resistance transporter, Uniprot Q9N623
DOI: 10.7270/q23r0vjn
title: BindingDB Entry 50045516: Synthesis and binding properties of new long-chain 4-substituted piperazine derivatives as 5-HT1A and 5-HT7 receptor ligands.

description: Small molecule binding data for protein 5-Hydroxytryptamine receptor 7 (5-HT7), 5-hydroxytryptamine receptor 1A, and Serotonin (5-HT) receptor, Uniprot P08908, P19327, and P34969
DOI: 10.7270/q2416zp1
title: BindingDB Entry 50045065: TBA

description: Small molecule binding data for protein 11-beta-hydroxysteroid dehydrogenase 1, Uniprot P28845 and P50172
DOI: 10.7270/q24j0gjb
title: BindingDB Entry 50043389: Toward the design of new DNA G-quadruplex ligands through rational analysis of polymorphism and binding data.

description: Small molecule binding data for protein Telomerase reverse transcriptase, Uniprot O14746
DOI: 10.7270/q2639r8m
title: BindingDB Entry 50044033: Design, synthesis and evaluation of a PLG tripeptidomimetic based on a pyridine scaffold.

description: Small molecule binding data for protein Dopamine receptor D2L/neurotensin receptor NTS1, Uniprot P14416
DOI: 10.7270/q26h4jzb
title: BindingDB Entry 50044538: Pivotal Role of an Aliphatic Side Chain in the Development of an HDM2 Inhibitor.

description: Small molecule binding data for protein Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), Cytochrome P450 3A, and E3 ubiquitin-protein ligase Mdm2, Uniprot P08684, P10635, P11712, and Q00987
DOI: 10.7270/q27h1m8c
title: BindingDB Entry 50045515: (18)F-AmBF3-MJ9: a novel radiofluorinated bombesin derivative for prostate cancer imaging.

description: Small molecule binding data for protein GRPR, Uniprot P30550 and X5D7H2
DOI: 10.7270/q27s7qdf
title: BindingDB Entry 50045064: TBA

description: Small molecule binding data for protein Transient receptor potential cation channel subfamily A member 1, Transient receptor potential cation channel subfamily M member 8, and Transient receptor potential cation channel subfamily V member 1, Uniprot O75762, Q8NER1, and Q8R4D5
DOI: 10.7270/q2891782
title: BindingDB Entry 50043388: Fragment-based discovery of focal adhesion kinase inhibitors.

description: Small molecule binding data for protein Cytochrome P450 1A, Cytochrome P450 2C19, Cytochrome P450 2C8, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), Focal adhesion kinase 1/vascular endothelial growth factor receptor 3, and PTK2B protein tyrosine kinase 2 beta (PTK2B), Uniprot P05177, P10632, P10635, P11712, P33261, Q05397, and Q14289
DOI: 10.7270/q29p33cm
title: BindingDB Entry 50046033: Development of novel CXC chemokine receptor 7 (CXCR7) ligands: selectivity switch from CXCR4 antagonists with a cyclic pentapeptide scaffold.

description: Small molecule binding data for protein C-X-C chemokine receptor type 4 (CXCR4) and C-X-C chemokine receptor type 7 (CXCR7), Uniprot P25106 and P61073
DOI: 10.7270/q2b859nm
title: BindingDB Entry 50044537: Himbacine-derived thrombin receptor antagonists: c7-spirocyclic analogues of vorapaxar.

description: Small molecule binding data for protein Proteinase-activated receptor 1 (PAR1), Uniprot P25116
DOI: 10.7270/q2c82c03
title: BindingDB Entry 50045514: New approaches to the synthesis of sildenafil analogues and their enzyme inhibitory activity.

description: Small molecule binding data for protein Carbonic anhydrase, Carbonic anhydrase 12, Carbonic anhydrase 2, Carbonic anhydrase 9, and Tyrosine-protein kinase ABL1, Uniprot O43570, P00519, P00915, P00918, and Q16790
DOI: 10.7270/q2cj8g3q
title: BindingDB Entry 50045063: TBA

description: Small molecule binding data for protein Kappa-type opioid receptor, Uniprot P41145
DOI: 10.7270/q2d22017
title: BindingDB Entry 50043387: Novel tetrahydropyran analogs as dipeptidyl peptidase IV inhibitors: profile of clinical candidate (2R,3S,5R)-2-(2,5-difluorophenyl)-5-[2-(methylsulfonyl)-2,6-dihydropyrrolo[3,4-c]pyrazol-5(4H)-yl]tetrahydro-2H-pyran-3-amine (23).

description: Small molecule binding data for protein Dipeptidyl peptidase VIII and Fibroblast activation protein alpha, Uniprot Q12884 and Q6V1X1
DOI: 10.7270/q2ff3v3z
title: BindingDB Entry 50046032: Synthesis of mixed opioid affinity cyclic endomorphin-2 analogues with fluorinated phenylalanines.

description: Small molecule binding data for protein Delta-type opioid receptor, Kappa-type opioid receptor, Mu-type opioid receptor, Nociceptin/mu opioid receptor, Opioid receptors; mu & delta, and mu/kappa opioid receptor, Uniprot P33533, P33535, P35372, P41143, P41144, and P41145
DOI: 10.7270/q2fn17pf
title: BindingDB Entry 50044031: Diaryl substituted pyrrolidinones and pyrrolones as 5-HT2C inhibitors: synthesis and biological evaluation.

description: Small molecule binding data for protein 5-Hydroxytryptamine receptor 2A (5-HT2A), 5-Hydroxytryptamine receptor 2C (5-HT2C), 5-Hydroxytryptamine receptor 6 (5-HT6), 5-Hydroxytryptamine receptor 7 (5-HT7), 5-hydroxytryptamine receptor 1A, 5-hydroxytryptamine receptor 1B, 5-hydroxytryptamine receptor 1D, Dopamine receptor, and Serotonin receptor (2b and 2c), Uniprot P08908, P28221, P28222, P28223, P28335, P34969, P35462, P41595, and P50406
DOI: 10.7270/q2g162cb
title: BindingDB Entry 50044536: Design, Synthesis, and Optimization of Balanced Dual NK1/NK3 Receptor Antagonists.

description: Small molecule binding data for protein Neurokinin 1 receptor and Neurokinin 3 receptor, Uniprot P25103 and P29371
DOI: 10.7270/q2h70hg5
title: BindingDB Entry 50045062: TBA

description: Small molecule binding data for protein Sodium-dependent dopamine transporter, Uniprot Q01959
DOI: 10.7270/q2jd4z8d
title: BindingDB Entry 50044038: Synthesis of novel thiourea, thiazolidinedione and thioparabanic acid derivatives of 4-aminoquinoline as potent antimalarials.

description: Small molecule binding data for protein Histidine-rich protein, Uniprot P05227
DOI: 10.7270/q2k64kt8
title: BindingDB Entry 50046031: Discovery of Benzimidazole CYP11B2 Inhibitors with in Vivo Activity in Rhesus Monkeys.

description: Small molecule binding data for protein Alpha-2B adrenergic receptor, Aromatase (CYP19), Calcium channel (Type L), Cytochrome P450 11B2, Cytochrome P450 17A1, Cytochrome P450 21, Cytochrome P450 3A, Steroid 11-beta-Hydroxylase (CYP11B1), and Voltage-gated sodium channel subunit Nav1.5, Uniprot P05093, P08684, P08686, P11511, P15538, P18089, P19099, Q13936, and Q14524
DOI: 10.7270/q2n0185f
title: BindingDB Entry 50045061: TBA

description: Small molecule binding data for protein Trypsin, Uniprot P00761
DOI: 10.7270/q2p55q04
title: BindingDB Entry 50044037: Isolation of 1-Methylherbipoline Salts of Halisulfate-1 and of Suvanine as Serine Protease Inhibitors from a Marine Sponge, Coscinoderma mathewsi

description: Small molecule binding data for protein Prothrombin, Uniprot P00734
DOI: 10.7270/q2pz5bjp
title: BindingDB Entry 50046030: Synthesis and Pharmacology ofa/ß(3)-Peptides Based on the Melanocortin Agonist Ac-His-dPhe-Arg-Trp-NH2 Sequence.

description: Small molecule binding data for protein Melanocortin receptor 1, Melanocortin receptor 3, Melanocortin receptor 4, and Melanocortin receptor 5 (MC5R), Uniprot P33033, P41149, P56450, and Q01727
DOI: 10.7270/q2qj7jv4
title: BindingDB Entry 50044534: Discovery of the Fibrinolysis Inhibitor AZD6564, Acting via Interference of a Protein-Protein Interaction.

description: Small molecule binding data for protein Cytochrome P450 1A, Cytochrome P450 2C19, Cytochrome P450 2C8, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), Cytochrome P450 3A, Plasminogen, and Voltage-gated potassium channel, Uniprot P00747, P05177, P08684, P10632, P10635, P11712, P33261, and Q12809
DOI: 10.7270/q2rf5wpj
title: BindingDB Entry 50045511: trans-3,4-Disubstituted pyrrolidines as inhibitors of the human aspartyl protease renin. Part II: prime site exploration using an oxygen linker.

description: Small molecule binding data for protein Alpha-1A adrenergic receptor, Alpha-2A adrenergic receptor, Alpha-2B adrenergic receptor, Beta-secretase 1, Beta-secretase 2 (BACE2), Cathepsin D, Cathepsin E, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), Cytochrome P450 3A, Mu-type opioid receptor, Pepsinogen A5, Pepsinogen C, Renin, and Voltage-gated potassium channel, Uniprot P00797, P07339, P08684, P08913, P0DJD9, P10635, P11712, P14091, P18089, P20142, P35348, P35372, P56817, Q12809, and Q9Y5Z0
DOI: 10.7270/q2tm7cw4
title: BindingDB Entry 50046029: (R)-2-Phenylpyrrolidine Substituted Imidazopyridazines: A New Class of Potent and Selective Pan-TRK Inhibitors.

description: Small molecule binding data for protein ALK tyrosine kinase receptor, Fibroblast growth factor receptor 3, Fibroblast growth factor receptor 4, Hepatocyte growth factor receptor, Insulin receptor, Insulin-like growth factor I receptor, Kinesin-1 heavy chain/ Tyrosine-protein kinase receptor RET, Macrophage colony stimulating factor receptor, Macrophage-stimulating protein receptor, NT-3 growth factor receptor, Neurotrophic tyrosine kinase receptor, Neurotrophic tyrosine kinase receptor type 2, Platelet-derived growth factor receptor beta, Proto-oncogene tyrosine-protein kinase MER, Proto-oncogene tyrosine-protein kinase ROS, RAF serine/threonine protein kinase, SRC, Tyrosine-protein kinase ABL1, Tyrosine-protein kinase BMX, Tyrosine-protein kinase JAK2, Tyrosine-protein kinase Kit (Kit), Tyrosine-protein kinase SYK, Tyrosine-protein kinase ZAP-70, Tyrosine-protein kinase receptor FLT3, Tyrosine-protein kinase receptor TYRO3, Tyrosine-protein kinase receptor Tie-1, VEGF-receptor 2 and tyrosine-protein kinase SRC, Vascular endothelial growth factor receptor, and Vascular endothelial growth factor receptor 2, Uniprot L7RSL3, O60674, P00519, P04629, P06213, P06239, P07333, P07948, P07949, P08069, P08581, P08922, P09619, P09769, P10721, P12931, P15056, P17948, P22455, P22607, P35590, P35968, P36888, P43403, P43405, P51813, Q04912, Q06418, Q12866, Q16288, Q16620, and Q9UM73
DOI: 10.7270/q2v989nr
title: BindingDB Entry 50044533: New Hits as Antagonists of GPR103 Identified by HTS.

description: Small molecule binding data for protein GPR103, Uniprot Q96P65
DOI: 10.7270/q2xp76fv
title: BindingDB Entry 50044035: Rapid novel divergent synthesis and muscarinic agonist profile of all four optical isomers of N,N,N-trimethyl(6-methyl-1,4-dioxan-2-yl)methanaminium iodide.

description: Small molecule binding data for protein Muscarinic acetylcholine receptor, Muscarinic acetylcholine receptor M1, Muscarinic acetylcholine receptor M1/M5 chimeric protein, Muscarinic acetylcholine receptor M2, and Muscarinic acetylcholine receptor M2 and M4, Uniprot P08172, P08173, P08912, P11229, and P20309
DOI: 10.7270/q2zc84mv
title: BindingDB Entry 50046028: Monocarboxylate transporter 1 inhibitors as potential anticancer agents.

description: Small molecule binding data for protein Monocarboxylate transporter 1 (MCT1), Uniprot P53987