cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.11880852
title: Supplementary Material for: Finerenone Reduces Intrinsic Arterial Stiffness in Munich Wistar Frömter Rats, a Genetic Model of Chronic Kidney Disease

description: <b><i>Background:</i></b> Development of albuminuria and arterial stiffness in Munich Wistar Frömter (MWF) rats, a model of chronic kidney disease, is related to alterations in extracellular matrix, increased oxidative stress, and endothelial dysfunction. Finerenone (FIN), a novel, nonsteroidal, potent, and selective mineralocorticoid receptor antagonist, improves endothelial dysfunction through enhancing nitric oxide (NO) bioavailability and decreasing superoxide anion levels due to an upregulation in vascular and renal superoxide dismutase activity. We hypothesize that FIN reduces arterial stiffness in this model associated to the reduction in albuminuria and matrix metalloproteinase (MMP)-2/9 activity. <b><i>Methods:</i></b> Twelve-week-old MWF rats with established albuminuria and age-matched normoalbuminuric Wistar (W) rats were treated with FIN (10 mg/kg/day, once-daily oral gavage) or with vehicle (control, C) for 4 weeks. <b><i>Results:</i></b> Arterial stiffness was significantly higher in mesenteric arteries (MA) of MWF-C as compared to W-C. FIN treatment significantly lowered β-index, a measure of intrinsic stiffness independent of geometry, in MWF (β<sub>MWF-FIN</sub> = 7.7 ± 0.4 vs. β<sub>MWF-C</sub> = 9.2 ± 0.5, <i>p</i> &lt; 0.05) positively correlating with urinary albumin excretion. Elastin fenestrae area in the internal elastic lamina of MA from MWF-FIN was significantly larger (+377%, <i>p</i> &lt; 0.05). FIN increased plasma pro-MMP-2 and decreased plasma MMP-2 and MMP-9 activities, correlating with reductions in β-index. MA from MWF-FIN exhibited higher NO bioavailability and reduced superoxide anion levels compared to MWF-C. <b><i>Conclusion:</i></b> FIN treatment reduces intrinsic arterial stiffness in MA from MWF rats associated with changes in elastin organization, normalization of MMP-2 and MMP-9 activities, and reduction of oxidative stress. Moreover, reduction of arterial stiffness correlates with reduction in albuminuria.
DOI: 10.6084/m9.figshare.11880849
title: Supplementary Material for: Circuit Survival during Continuous Venovenous Hemodialysis versus Continuous Venovenous Hemofiltration

description: <b><i>Background:</i></b> Continuous renal replacement therapy (CRRT) technique may affect circuit lifespan. A shorter circuit life may reduce CRRT efficacy and increase costs. <b><i>Methods:</i></b> In a before-and-after study, we compared circuit median survival time during continuous venovenous hemofiltration (CVVH) versus continuous venovenous hemodialysis (­CVVHD). We performed log-rank mixed effects univariate analysis and Cox mixed effect regression modeling to define predictors of circuit lifespan. <b><i>Results:</i></b> We compared 197 ­CVVHD and 97 CVVH circuits in 39 patients. There was no overall difference in circuit lifespan. When no anticoagulation was used, median circuit survival time was shorter for CVVH circuits (5 h, 95% CI 3–7 vs. 10 h, 95% CI 8–13, <i>p</i> &lt; 0.01). Moreover, CVVHD, lower platelets levels, and longer activated partial thromboplastin time independently predicted longer circuit median survival time. <b><i>Conclusions:</i></b> CVVHD is associated with longer circuit median survival time than CVVH when no anticoagulation is used and is an independent predictor of circuit survival.
DOI: 10.6084/m9.figshare.11880852.v1
title: Supplementary Material for: Finerenone Reduces Intrinsic Arterial Stiffness in Munich Wistar Frömter Rats, a Genetic Model of Chronic Kidney Disease

description: <b><i>Background:</i></b> Development of albuminuria and arterial stiffness in Munich Wistar Frömter (MWF) rats, a model of chronic kidney disease, is related to alterations in extracellular matrix, increased oxidative stress, and endothelial dysfunction. Finerenone (FIN), a novel, nonsteroidal, potent, and selective mineralocorticoid receptor antagonist, improves endothelial dysfunction through enhancing nitric oxide (NO) bioavailability and decreasing superoxide anion levels due to an upregulation in vascular and renal superoxide dismutase activity. We hypothesize that FIN reduces arterial stiffness in this model associated to the reduction in albuminuria and matrix metalloproteinase (MMP)-2/9 activity. <b><i>Methods:</i></b> Twelve-week-old MWF rats with established albuminuria and age-matched normoalbuminuric Wistar (W) rats were treated with FIN (10 mg/kg/day, once-daily oral gavage) or with vehicle (control, C) for 4 weeks. <b><i>Results:</i></b> Arterial stiffness was significantly higher in mesenteric arteries (MA) of MWF-C as compared to W-C. FIN treatment significantly lowered β-index, a measure of intrinsic stiffness independent of geometry, in MWF (β<sub>MWF-FIN</sub> = 7.7 ± 0.4 vs. β<sub>MWF-C</sub> = 9.2 ± 0.5, <i>p</i> &lt; 0.05) positively correlating with urinary albumin excretion. Elastin fenestrae area in the internal elastic lamina of MA from MWF-FIN was significantly larger (+377%, <i>p</i> &lt; 0.05). FIN increased plasma pro-MMP-2 and decreased plasma MMP-2 and MMP-9 activities, correlating with reductions in β-index. MA from MWF-FIN exhibited higher NO bioavailability and reduced superoxide anion levels compared to MWF-C. <b><i>Conclusion:</i></b> FIN treatment reduces intrinsic arterial stiffness in MA from MWF rats associated with changes in elastin organization, normalization of MMP-2 and MMP-9 activities, and reduction of oxidative stress. Moreover, reduction of arterial stiffness correlates with reduction in albuminuria.
DOI: 10.6084/m9.figshare.11880846
title: Thermal-hydraulic analysis on quench behavior of indium-tin soldered REBCO composite conductor

description: data of Thermal-hydraulic analysis on quench behavior of indium-tin soldered REBCO composite conductor
DOI: 10.6084/m9.figshare.11880849.v1
title: Supplementary Material for: Circuit Survival during Continuous Venovenous Hemodialysis versus Continuous Venovenous Hemofiltration

description: <b><i>Background:</i></b> Continuous renal replacement therapy (CRRT) technique may affect circuit lifespan. A shorter circuit life may reduce CRRT efficacy and increase costs. <b><i>Methods:</i></b> In a before-and-after study, we compared circuit median survival time during continuous venovenous hemofiltration (CVVH) versus continuous venovenous hemodialysis (­CVVHD). We performed log-rank mixed effects univariate analysis and Cox mixed effect regression modeling to define predictors of circuit lifespan. <b><i>Results:</i></b> We compared 197 ­CVVHD and 97 CVVH circuits in 39 patients. There was no overall difference in circuit lifespan. When no anticoagulation was used, median circuit survival time was shorter for CVVH circuits (5 h, 95% CI 3–7 vs. 10 h, 95% CI 8–13, <i>p</i> &lt; 0.01). Moreover, CVVHD, lower platelets levels, and longer activated partial thromboplastin time independently predicted longer circuit median survival time. <b><i>Conclusions:</i></b> CVVHD is associated with longer circuit median survival time than CVVH when no anticoagulation is used and is an independent predictor of circuit survival.
DOI: 10.6084/m9.figshare.11880846.v1
title: Thermal-hydraulic analysis on quench behavior of indium-tin soldered REBCO composite conductor

description: data of Thermal-hydraulic analysis on quench behavior of indium-tin soldered REBCO composite conductor
DOI: 10.6084/m9.figshare.11880834
title: Aligned fasta data for Rhizophagus phylogeny

description: Aligned fasta for <i>Rhizophagus</i> phylogeny construction in the referenced article.
DOI: 10.6084/m9.figshare.11880834.v1
title: Aligned fasta data for Rhizophagus phylogeny

description: Aligned fasta for <i>Rhizophagus</i> phylogeny construction in the referenced article.
DOI: 10.6084/m9.figshare.11880786
title: Synthesis and photophysical properties of conjugated thioketone, thioketone <i>S</i>-oxide (Sulfine), and related compounds incorporated in a dibenzobarrelene skeleton

description: Conjugated thioketone and thioketone <i>S</i>-oxide (sulfine) were synthesized from the corresponding ketone conjugated to a 1,3-butadiene system incorporated in a dibenzobarrelene skeleton. The conjugated thioketone was obtained by the reaction of the corresponding diazo compound with elemental sulfur, the oxidation of which with <i>m</i>-chloroperoxybenzoic acid provided the conjugated sulfine as a mixture of (<i>Z</i>)- and (<i>E</i>)-stereoisomers. (<i>E</i>)-Sulfine gradually isomerized to (<i>Z</i>)-sulfine in solution in the dark. Photoisomerization between (<i>Z</i>)- and (<i>E</i>)-sulfines was observed under photoirradiation together with the desulfurization to the corresponding ketone. The conjugated thioketone showed the weak long-wavelength absorption at 626 nm due to the n-π* excitation in the optical absorption spectrum and nonphotoluminescent. The conjugated (<i>Z</i>)-sulfine exhibited the long-wavelength absorption at 448 nm due to the π-π* excitation and very weak photoluminescence at 489 nm with the quantum yield of 0.002 at room temperature. The weak photoluminescence was enhanced in EtOH at 77 K showing yellow luminescence, and the quantum yield increased to 0.32. Lifetime values of the luminescence (2.4 and 6.8 ns) at 77 K suggests that the luminescence is fluorescence. A large solvent effect and a similar temperature dependency of photoluminescence were observed for the conjugated ketone.
DOI: 10.6084/m9.figshare.11880780
title: Rhizophagus 48S rDNA sequences for Neighbor-net tree

description: Aligned sequences used for Neighbor-net tree construction in the referenced article.
DOI: 10.6084/m9.figshare.11880786.v1
title: Synthesis and photophysical properties of conjugated thioketone, thioketone <i>S</i>-oxide (Sulfine), and related compounds incorporated in a dibenzobarrelene skeleton

description: Conjugated thioketone and thioketone <i>S</i>-oxide (sulfine) were synthesized from the corresponding ketone conjugated to a 1,3-butadiene system incorporated in a dibenzobarrelene skeleton. The conjugated thioketone was obtained by the reaction of the corresponding diazo compound with elemental sulfur, the oxidation of which with <i>m</i>-chloroperoxybenzoic acid provided the conjugated sulfine as a mixture of (<i>Z</i>)- and (<i>E</i>)-stereoisomers. (<i>E</i>)-Sulfine gradually isomerized to (<i>Z</i>)-sulfine in solution in the dark. Photoisomerization between (<i>Z</i>)- and (<i>E</i>)-sulfines was observed under photoirradiation together with the desulfurization to the corresponding ketone. The conjugated thioketone showed the weak long-wavelength absorption at 626 nm due to the n-π* excitation in the optical absorption spectrum and nonphotoluminescent. The conjugated (<i>Z</i>)-sulfine exhibited the long-wavelength absorption at 448 nm due to the π-π* excitation and very weak photoluminescence at 489 nm with the quantum yield of 0.002 at room temperature. The weak photoluminescence was enhanced in EtOH at 77 K showing yellow luminescence, and the quantum yield increased to 0.32. Lifetime values of the luminescence (2.4 and 6.8 ns) at 77 K suggests that the luminescence is fluorescence. A large solvent effect and a similar temperature dependency of photoluminescence were observed for the conjugated ketone.
DOI: 10.6084/m9.figshare.11880768
title: picoplankton and virioplankton data

description: Original documents of flow cytometry of picoplankton and virioplankton in seamount
DOI: 10.6084/m9.figshare.11880780.v2
title: Rhizophagus 48S rDNA sequences for Neighbor-net tree

description: Aligned sequences used for Neighbor-net tree construction in the referenced article.
DOI: 10.6084/m9.figshare.11880768.v1
title: picoplankton and virioplankton data

description: Original documents of flow cytometry of picoplankton and virioplankton in seamount
DOI: 10.6084/m9.figshare.11880780.v1
title: Rhizophagus 48S rDNA sequences for Neighbor-net tree

description: Aligned sequences used for Neighbor-net tree construction in the referenced article.
DOI: 10.6084/m9.figshare.11880696
title: MQE

description: Thermal-hydraulic analysis on quench behavior of indium-tin soldered REBCO composite conductor
DOI: 10.6084/m9.figshare.11880696.v1
title: MQE

description: Thermal-hydraulic analysis on quench behavior of indium-tin soldered REBCO composite conductor
DOI: 10.6084/m9.figshare.11880657
title: Supplementary files 2 and 3 for "Linking health facility data from young adults aged 18-24 years to longitudinal demographic data: Experience from The Kilifi Health and Demographic Surveillance System"

description: Supplementary files for the submitted manuscript <i>Linking health facility data from young adults aged 18-24 years to longitudinal demographic data: Experience from The Kilifi Health and Demographic Surveillance System </i><br><i><br></i>Supplementary file 2 is the form used to collect demographic data from Unmatched participants<br>Supplementary file 3 contains Unmatched Participants data. Variable description is as follows: Data clerk: Study staff who did the consenting, searched and linked study participant’s demographic data with the clinic visit data; Hmname: Homestead name. Name a by which a homestead is known and referred to; HmHead: Homestead head. The person who heads a home, and makes important decisions for the family; Location: Administrative unit in the government structure headed by a chief; Sublocation: A sub-unit of a location headed by an assistant chief; Ehtnicity: Ethnic group; Facility: Health facility name; Date: date information was collected.
DOI: 10.6084/m9.figshare.11880648
title: Culm development and shape differentiation determined from transcriptome profiles of two types of Dendrocalamus sinicus

description: Dendrocaramus sinicus, known as the strongest bamboo in the world, has excellent potential for producing timber. Two variants, straight culm and bent culm, which are found throughout the species distribution area, are excellent materials for studying culm-shape variation and culm development of woody bamboos. However, the lack of genomic information has limited genetic studies in D. sinicus. Here, we performed transcriptome analysis of two types of D. sinicus.These high-quality data provide valuable gene annotation for culm-shape differentiation and culm development of woody bamboo.
DOI: 10.6084/m9.figshare.11880648.v1
title: Culm development and shape differentiation determined from transcriptome profiles of two types of Dendrocalamus sinicus

description: Dendrocaramus sinicus, known as the strongest bamboo in the world, has excellent potential for producing timber. Two variants, straight culm and bent culm, which are found throughout the species distribution area, are excellent materials for studying culm-shape variation and culm development of woody bamboos. However, the lack of genomic information has limited genetic studies in D. sinicus. Here, we performed transcriptome analysis of two types of D. sinicus.These high-quality data provide valuable gene annotation for culm-shape differentiation and culm development of woody bamboo.
DOI: 10.6084/m9.figshare.11880657.v2
title: Supplementary files 2 and 3 for "Linking health facility data from young adults aged 18-24 years to longitudinal demographic data: Experience from The Kilifi Health and Demographic Surveillance System"

description: Supplementary files for the submitted manuscript <i>Linking health facility data from young adults aged 18-24 years to longitudinal demographic data: Experience from The Kilifi Health and Demographic Surveillance System </i><br><i><br></i>Supplementary file 2 is the form used to collect demographic data from Unmatched participants<br>Supplementary file 3 contains Unmatched Participants data. Variable description is as follows: Data clerk: Study staff who did the consenting, searched and linked study participant’s demographic data with the clinic visit data; Hmname: Homestead name. Name a by which a homestead is known and referred to; HmHead: Homestead head. The person who heads a home, and makes important decisions for the family; Location: Administrative unit in the government structure headed by a chief; Sublocation: A sub-unit of a location headed by an assistant chief; Ehtnicity: Ethnic group; Facility: Health facility name; Date: date information was collected.
DOI: 10.6084/m9.figshare.11880582
title: URD object

description: URD object
DOI: 10.6084/m9.figshare.11880657.v1
title: Supplementary files 1 and 2 for "Linking health facility data from young adults aged 18-24 years to longitudinal demographic data: Experience from The Kilifi Health and Demographic Surveillance System"

description: Supplementary files for the submitted manuscript <i>Linking health facility data from young adults aged 18-24 years to longitudinal demographic data: Experience from The Kilifi Health and Demographic Surveillance System </i><br><i><br></i>Supplementary file 2 is the form used to collect demographic data from Unmatched participants<br>Supplementary file 3 contains Unmatched Participants data. Variable description is as follows: Data clerk: Study staff who did the consenting, searched and linked study participant’s demographic data with the clinic visit data; Hmname: Homestead name. Name a by which a homestead is known and referred to; HmHead: Homestead head. The person who heads a home, and makes important decisions for the family; Location: Administrative unit in the government structure headed by a chief; Sublocation: A sub-unit of a location headed by an assistant chief; Ehtnicity: Ethnic group; Facility: Health facility name; Date: date information was collected.
DOI: 10.6084/m9.figshare.11880564
title: Bulk gene expression

description: including raw counts and TPM which calculated by RSEM
DOI: 10.6084/m9.figshare.11880576
title: An analysis of DMPs for factors proposed to be associated with their efficacy as research tools

description: An analysis of data management plans (DMP) at an Australian institution. <br>The 834 DMPs sampled were a random subset of those extracted from a population of 1986 on the University's DMP system in November 2017.<br>DMPs were analysed across several criteria, including:- Detail and quality of information provided about physical and digital data storage.- Attitude/effort towards DMP completion and writing quality.- Data type clarity and findability.<br>Of 834 DMPs sampled, 21 were excluded because they were identified as being test submissions. 813 were subsequently included in the analysis.<br>Due to the impracticability of anonymising the raw data and institutional sensitivity, only the results of the analysis are available upon request.<br>Detailed background, methods, results and discussion are provided in an associated manuscript.
DOI: 10.6084/m9.figshare.11880576.v1
title: An analysis of DMPs for factors proposed to be associated with their efficacy as research tools

description: An analysis of data management plans (DMP) at an Australian institution. <br>The 834 DMPs sampled were a random subset of those extracted from a population of 1986 on the University's DMP system in November 2017.<br>DMPs were analysed across several criteria, including:- Detail and quality of information provided about physical and digital data storage.- Attitude/effort towards DMP completion and writing quality.- Data type clarity and findability.<br>Of 834 DMPs sampled, 21 were excluded because they were identified as being test submissions. 813 were subsequently included in the analysis.<br>Due to the impracticability of anonymising the raw data and institutional sensitivity, only the results of the analysis are available upon request.<br>Detailed background, methods, results and discussion are provided in an associated manuscript.
DOI: 10.6084/m9.figshare.11880564.v1
title: Bulk gene expression

description: including raw counts and TPM which calculated by RSEM
DOI: 10.6084/m9.figshare.11880447
title: Additional file 2 of Copper exposure in medieval and post-medieval Denmark and northern Germany: its relationship to residence location and social position

description: Additional file 2 Results of the chemical analysis of the soil samples procured in proximity to the three different skeletons. Concentrations are given in µg g−1. The uncertainty quoted is ± 1 standard deviation. Analyses of cortical (CO) and trabecular (TR) tissue of the skeletons are also listed. Vertical profiles are coloured green, horizontal soil profiles are coloured orange.
DOI: 10.6084/m9.figshare.11880447.v1
title: Additional file 2 of Copper exposure in medieval and post-medieval Denmark and northern Germany: its relationship to residence location and social position

description: Additional file 2 Results of the chemical analysis of the soil samples procured in proximity to the three different skeletons. Concentrations are given in µg g−1. The uncertainty quoted is ± 1 standard deviation. Analyses of cortical (CO) and trabecular (TR) tissue of the skeletons are also listed. Vertical profiles are coloured green, horizontal soil profiles are coloured orange.
DOI: 10.6084/m9.figshare.11880441
title: Additional file 1 of Copper exposure in medieval and post-medieval Denmark and northern Germany: its relationship to residence location and social position

description: Additional file 1. Results of the chemical analysis of the bone samples. Concentrations are given in µg g−1 except for Ca which is given in wt%. The uncertainty quoted is ± 1 standard deviation. When below LOQ, the result is designated
DOI: 10.6084/m9.figshare.11880441.v1
title: Additional file 1 of Copper exposure in medieval and post-medieval Denmark and northern Germany: its relationship to residence location and social position

description: Additional file 1. Results of the chemical analysis of the bone samples. Concentrations are given in µg g−1 except for Ca which is given in wt%. The uncertainty quoted is ± 1 standard deviation. When below LOQ, the result is designated
DOI: 10.6084/m9.figshare.11880411
title: Additional file 2 of No raw data, no science: another possible source of the reproducibility crisis

description: Additional file 2: Table S1. List of the 41 manuscripts that received editorial decision, "Revise before review”, for the reason that the results looked “too beautiful”.
DOI: 10.6084/m9.figshare.11880411.v1
title: Additional file 2 of No raw data, no science: another possible source of the reproducibility crisis

description: Additional file 2: Table S1. List of the 41 manuscripts that received editorial decision, "Revise before review”, for the reason that the results looked “too beautiful”.
DOI: 10.6084/m9.figshare.11880393
title: Additional file 1 of Author Correction: Interaction between the microbiome and TP53 in human lung cancer

description: Additional file 5. Clinical metadata and OTUs for NCI-MD samples.
DOI: 10.6084/m9.figshare.11880303
title: wuzi.rmdup.bam

description: The “wuzi.rmdup.bam” was the resequencing dataset of ‘Wuzishatangju’. You can install the software “savant-windows-installer-2.0.5”, and download the reference genome (<i>C. clementina</i>) from the database “https://phytozome.jgi.doe.gov/pz/portal.html” <b>or</b> “https://www.citrusgenomedb.org/”. Then scan the resequencing dataset and reference genome.
DOI: 10.6084/m9.figshare.11879832
title: Data from Durkin et al 2020 - JoIB.xlsx

description: This file contains data for three assays on activity level (# of lines crossed) and three assays on attachment propensity for mites from two populations.<br>
DOI: 10.6084/m9.figshare.11880303.v1
title: wuzi.rmdup.bam

description: The “wuzi.rmdup.bam” was the resequencing dataset of ‘Wuzishatangju’. You can install the software “savant-windows-installer-2.0.5”, and download the reference genome (<i>C. clementina</i>) from the database “https://phytozome.jgi.doe.gov/pz/portal.html” <b>or</b> “https://www.citrusgenomedb.org/”. Then scan the resequencing dataset and reference genome.
DOI: 10.6084/m9.figshare.11880393.v1
title: Additional file 1 of Author Correction: Interaction between the microbiome and TP53 in human lung cancer

description: Additional file 5. Clinical metadata and OTUs for NCI-MD samples.