cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.11930397.v2
title: A review of Australia’s Mesozoic fishes

description: The Australian Mesozoic fish fauna is considered to be depauperate in comparison with fish faunas in the Northern Hemisphere. However, due to its geographical location as a potential radiation center in the Southern Hemisphere, Australia’s Mesozoic fish fauna is important for understanding fish radiations. Most of the modern fish groups originated during the Mesozoic, but the first records of a modern fish fauna (freshwater and marine) in Australia does not occur until the lower Paleogene. Here, we review all known fossil fish-bearing localities from the Mesozoic of Australia, to improve the understanding of the record. The apparent low Australian Mesozoic fish diversity is likely due to its understudied status of the constituent fossils rather than to a depauperate record. In addition, we review recent work with the aim of placing the Australian Mesozoic fish fauna in a global context. We review the taxonomy of Australian fossil fishes and conclude that the assignments of many actinopterygians need major revision within a modern phylogenetic context. The vast majority of chondrichthyans are yet to be formally described; to the contrary all of the known lungfish specimens have been described. This study considers the microscopic and fragmented remains of Mesozoic fish already found in Australia, allowing a more complete view of the diversity of the fishes that once inhabited this continent. Rodney W. Berrell [r.berrell@postgrad.curtin.edu.au], School of Earth and Planetary Sciences, Curtin University, Kent Street, Bentley, Western Australia, 6102, Australia; Catherine Boisvert [Catherine.Boisvert@curtin.edu.au], School of Molecular and Life Sciences (MLS), Curtin University, Kent Street, Bentley, Western Australia, 6102, Australia; Kate Trinajstic [K.Trinajstic@curtin.edu.au], School of Molecular and Life Sciences (MLS), Curtin University, Kent Street, Bentley, Western Australia, 6102, Australia; Mikael Siversson# [mikael.siversson@museum.wa.gov.au], Department of Earth and Planetary Sciences, Western Australian Museum, 49 Kew Street, Welshpool, Western Australia, 6106, Australia; Jesús Alvarado-Ortega [jalvarado@yahoo.com.mx], Instituto Geologia Cd universitaria, Circuito de la investigacion, Del. coyoacan, C.P. 04510, Ciudad de México, México; Lionel Cavin [lionel.cavin@ville-ge.ch], Section of Earth Sciences, Muséum d’Histoire naturelle de la Ville de Genèeve, CP 6434, 1211 Genève 6, Switzerland; Steven W. Salisbury [s.salisbury@uq.edu.au], School of Biological Sciences, The University of Queensland, Brisbane St Lucia, Queensland, 4072, Australia; Anne Kemp [annerkemp@gmail.com], 9 Hampton Grove, Norwood, Adelaide, South Australia 5067, Australia. #Also affiliated with: School of Molecular and Life Sciences, Curtin University, Kent Street, Bentley, WA 6102, Australia.
DOI: 10.6084/m9.figshare.11930376
title: Butter-weld Interface Microstructural Analysis Employing NCS and LAMS Sections

description: The formation of brittle microstructures around the fusion line in dissimilar welds has required a deeper microstructural analysis in this region. The study becomes more relevant when these welds are used in environments that facilitate hydrogen embrittlement. The present work aims to characterize the microstructure and hardness at the diluted zone interface in joints welded with dissimilar materials. Aiming for a better efficacy in the microstructural characterization of this zone, samples of both normal cross-section (NCS) and section with slope were used, according to the low-angle microsectioning (LAMS) technique, which allows a greater amplification of partially mixed zones (PMZs). The results indicated the diffusion of carbon from the heat-affected zone (HAZ) towards the fusion line which, in combination with other alloying elements, form highly brittle carbides. In turn, the hardness of the base metal and the HAZ was reduced after post weld heat treatment, whereas in the weld metal an opposite behavior was observed. The dissimilar interface was promising for applications in environments facilitating hydrogen embrittlement, especially regarding the characteristics of zone Φ.
DOI: 10.6084/m9.figshare.11930376.v1
title: Butter-weld Interface Microstructural Analysis Employing NCS and LAMS Sections

description: The formation of brittle microstructures around the fusion line in dissimilar welds has required a deeper microstructural analysis in this region. The study becomes more relevant when these welds are used in environments that facilitate hydrogen embrittlement. The present work aims to characterize the microstructure and hardness at the diluted zone interface in joints welded with dissimilar materials. Aiming for a better efficacy in the microstructural characterization of this zone, samples of both normal cross-section (NCS) and section with slope were used, according to the low-angle microsectioning (LAMS) technique, which allows a greater amplification of partially mixed zones (PMZs). The results indicated the diffusion of carbon from the heat-affected zone (HAZ) towards the fusion line which, in combination with other alloying elements, form highly brittle carbides. In turn, the hardness of the base metal and the HAZ was reduced after post weld heat treatment, whereas in the weld metal an opposite behavior was observed. The dissimilar interface was promising for applications in environments facilitating hydrogen embrittlement, especially regarding the characteristics of zone Φ.
DOI: 10.6084/m9.figshare.11930370
title: PRIVATE AUTHORITY IN INTERNET GOVERNANCE: NAME AND DOMAIN REGIMES IN THE LATIN AMERICAN CONTEXT

description: This paper offers comparative research on four different models of multistakeholder governance for the critical resources of the Internet (v. g. national top-level domains or ccTLDs) in Brazil, Colombia, Argentina, and Mexico, while engaging with the ongoing debate over Internet governance and its relations with emerging forms of private authority. Based on an extensive range of interviews with governmental and non-governmental actors, it argues that multistakeholderism may function as a specific rule of authority for the national regimes of Internet Governance. This hypothesis suggests a profound transformation in the modern structures of governing since heterarchy replaces hierarchy in the building of regulatory arrangements.
DOI: 10.6084/m9.figshare.11930373
title: Synthesis of a Ce-Based MOF-76 with High Yield: A Study of Reaction Parameters Based on a Factorial Design

description: The purpose of this work was to optimize the synthesis yield of {[Ce(BTC)(H2O)]·DMF}n, a metal-organic framework (MOF)-76 family member, by solvothermal method. CeCl3.7H2O and 1,3,5-benzenetricarboxylic acid, 2:1 molar proportion, were added to N, N-dimethylformamide (DMF). Reaction time and temperature were evaluated to optimize the synthesis through a factorial design followed by a statistical analysis of the response variable (reaction yield). Infrared spectroscopy (IR), X-ray diffraction (XRD), thermogravimetric analysis (TGA), scanning electron microscopy (SEM) and Brunauer-Emmett-Teller (BET) analyses were performed to characterize the obtained white powders. Reaction yield was estimated based on {[Ce(BTC)(H2O)]·DMF}n molecular formula, which was confirmed by analytical techniques. The proposed statistic model of the response variable showed good agreement with the experimental values. Temperature parameter was the only significant variable on the reaction yields, being the highest yield (94.4%) obtained at 115 ºC for 36 h, and it was accompanied by an improvement on the particle morphology (uniformity of shape and size), forming particles with strawsheave-like morphology.
DOI: 10.6084/m9.figshare.11930379.v1
title: Determination, through Derivatization and GC-MS Analysis, of Omega-3 and Omega-6 Fatty Acids in Fish Oil Capsules Sold in Salvador, Bahia

description: The essential w-3 and w-6 fatty acids have important physiological functions, such as prevention of cardiovascular diseases and atherosclerosis, and are commercially sold as fish oil capsules. In the present work, a method previously described in the literature, based on the derivatization of polyunsaturated fatty acids and their gas chromatography-mass spectrometry (GC-MS) analysis in the form of methyl esters, was partially modified and optimized for determination of w-3 and w-6 fatty acids in fish oil capsules. In addition, the w-9 fatty acid oleic acid was also determined with the optimized method, despite the lack of information about its quantities in the acquired products. The method exhibited good linearity and precision, limits of detection and quantification in the ranges from 0.16 to 0.18 mg g-1 and 0.46 to 0.63 mg g-1, respectively, and recoveries above 76%. The method was applied to analyze ten brands of encapsulated fish oil marketed in Salvador, BA, Brazil. Amongst the results, it was shown that one brand had significantly high amounts of linoleic acid, which indicates a probable adulteration of the product.
DOI: 10.6084/m9.figshare.11930370.v1
title: PRIVATE AUTHORITY IN INTERNET GOVERNANCE: NAME AND DOMAIN REGIMES IN THE LATIN AMERICAN CONTEXT

description: This paper offers comparative research on four different models of multistakeholder governance for the critical resources of the Internet (v. g. national top-level domains or ccTLDs) in Brazil, Colombia, Argentina, and Mexico, while engaging with the ongoing debate over Internet governance and its relations with emerging forms of private authority. Based on an extensive range of interviews with governmental and non-governmental actors, it argues that multistakeholderism may function as a specific rule of authority for the national regimes of Internet Governance. This hypothesis suggests a profound transformation in the modern structures of governing since heterarchy replaces hierarchy in the building of regulatory arrangements.
DOI: 10.6084/m9.figshare.11930358
title: WHAT HAS CHANGED A new farewell to the working class?

description: ABSTRACTS This paper aims to discuss the thesis supported by several scholars and institutions according to which capitalist societies have been through a sharp shift in the nature of work relations. It assumes that social and economic changes in work management and new technologies would have dissolved traditional forms of employment, and the consequence would be a decline in wage labor. This new ‘farewell to the working class’ contributes to the idea that it is impossible to protect workers via public regulation. Based on empirical research using several case studies and data, especially from labor markets in Brazil and the United Kingdom, we argue that the “new” forms of work are predominantly wage labor, despite companies’ efforts to disguise the content of employment relations. We do not deny the emergence of changes in labor management by companies. However, we point out that this includes strategies of dissimulation of the wage relationship to reduce chances of limiting labor exploitation.
DOI: 10.6084/m9.figshare.11930358.v1
title: WHAT HAS CHANGED A new farewell to the working class?

description: ABSTRACTS This paper aims to discuss the thesis supported by several scholars and institutions according to which capitalist societies have been through a sharp shift in the nature of work relations. It assumes that social and economic changes in work management and new technologies would have dissolved traditional forms of employment, and the consequence would be a decline in wage labor. This new ‘farewell to the working class’ contributes to the idea that it is impossible to protect workers via public regulation. Based on empirical research using several case studies and data, especially from labor markets in Brazil and the United Kingdom, we argue that the “new” forms of work are predominantly wage labor, despite companies’ efforts to disguise the content of employment relations. We do not deny the emergence of changes in labor management by companies. However, we point out that this includes strategies of dissimulation of the wage relationship to reduce chances of limiting labor exploitation.
DOI: 10.6084/m9.figshare.11930349
title: Large miRNA survival analysis reveals a prognostic four-biomarker signature for triple negative breast cancer

description: Abstract Triple negative breast cancer (TNBC) is currently the only major breast tumor subtype without effective targeted therapy and, as a consequence, usually presents a poor outcome. Due to its more aggressive phenotype, there is an urgent clinical need to identify novel biomarkers that discriminate individuals with poor prognosis. We hypothesize that miRNAs can be used to this end because they are involved in the initiation and progression of tumors by altering the expression of their target genes. To identify a prognostic biomarker in TNBC, we analyzed the miRNA expression of a cohort composed of 185 patients diagnosed with TNBC using penalized Cox regression models. We identified a four-biomarker signature based on miR-221, miR-1305, miR-4708, and RMDN2 expression levels that allowed for the subdivision of TNBC into high- or low-risk groups (Hazard Ratio – HR = 0.32; 95% Confidence Interval - CI = 0.11–0.91; p = 0.03) and are also statistically associated with survival outcome in subgroups of postmenopausal status (HR = 0.19; 95% CI = 0.04–0.90; p= 0.016), node negative status (HR = 0.12; 95% CI = 0.01–1.04; p = 0.026), and tumors larger than 2cm (HR = 0.21; 95% CI = 0.05–0.81; p = 0.021). This four-biomarker signature was significantly associated with TNBC as an independent prognostic factor for survival.
DOI: 10.6084/m9.figshare.11930352
title: Identifying New Isatin Derivatives with GSK-3β Inhibition Capacity through Molecular Docking and Bioassays

description: The semi-synthesis of 11 isatin derivatives was achieved through bimolecular nucleophilic substitution and click chemistry. Seven new compounds were obtained. All chemical structures were determined by infrared spectroscopy (IR), nuclear magnetic resonance spectrometry (NMR) and high-resolution mass spectrometry (HRMS) data. These derivatives were evaluated for their anti-GSK-3b activity and all isatin derivatives (N-alkyl and 1,2,3-triazolic) exhibited strong inhibitory activity, with 2b and 4h exhibiting remarkable potency. In addition, docking studies were performed with 2b and 2e models to unravel the molecular mechanism underlying the polar interactions on the GSK-3b ATP-binding site.
DOI: 10.6084/m9.figshare.11930355
title: TD-DFT Analysis of the Dissymmetry Factor in Camphor

description: The fact that the dissymmetry lgeb (g-factor) of camphor is large has been known for decades, and the interpretation of the observed data has also been known for a long time. However, due to the ability of quantum chemical methods to describe chiroptical phenomena more appropriately, additional approaches based on these methods have been successful employed. The g-factor lgebra in S-camphor and L-tryptophan have been investigated by UV-Vis and electronic circular dichroism (ECD) spectroscopies of the n ® p* electronic transition. Time-dependent density functional theory (TD-DFT) calculations at CAM-B3LYP/6-311++G(3df,2p)//B3LYP/6-311++G(2d,p) level of theory including Grimme’s dispersion effects have been performed. The lgebra effect was added using solvation model based on density (SMD) approach in solvation environment. The results permit insights into the ground and excited states electronic properties associated with the g-factor. The theoretical spectra showed good similarity with the experimental ones. The theoretical ECD of camphor was found at 282 nm, whereas the experimental shows its maximum at 290 nm. Regarding the maximum value of the molar absorptivity lgebrante, the theoretical and experimental values were 16.2 and 30.2 M-1 cm-1, respectively. The same concordance was obtained for g-factor, as follows: -0.0445 and -0.0886, for experimental and theoretical results, respectively.
DOI: 10.6084/m9.figshare.11930352.v1
title: Identifying New Isatin Derivatives with GSK-3β Inhibition Capacity through Molecular Docking and Bioassays

description: The semi-synthesis of 11 isatin derivatives was achieved through bimolecular nucleophilic substitution and click chemistry. Seven new compounds were obtained. All chemical structures were determined by infrared spectroscopy (IR), nuclear magnetic resonance spectrometry (NMR) and high-resolution mass spectrometry (HRMS) data. These derivatives were evaluated for their anti-GSK-3b activity and all isatin derivatives (N-alkyl and 1,2,3-triazolic) exhibited strong inhibitory activity, with 2b and 4h exhibiting remarkable potency. In addition, docking studies were performed with 2b and 2e models to unravel the molecular mechanism underlying the polar interactions on the GSK-3b ATP-binding site.
DOI: 10.6084/m9.figshare.11930349.v1
title: Large miRNA survival analysis reveals a prognostic four-biomarker signature for triple negative breast cancer

description: Abstract Triple negative breast cancer (TNBC) is currently the only major breast tumor subtype without effective targeted therapy and, as a consequence, usually presents a poor outcome. Due to its more aggressive phenotype, there is an urgent clinical need to identify novel biomarkers that discriminate individuals with poor prognosis. We hypothesize that miRNAs can be used to this end because they are involved in the initiation and progression of tumors by altering the expression of their target genes. To identify a prognostic biomarker in TNBC, we analyzed the miRNA expression of a cohort composed of 185 patients diagnosed with TNBC using penalized Cox regression models. We identified a four-biomarker signature based on miR-221, miR-1305, miR-4708, and RMDN2 expression levels that allowed for the subdivision of TNBC into high- or low-risk groups (Hazard Ratio – HR = 0.32; 95% Confidence Interval - CI = 0.11–0.91; p = 0.03) and are also statistically associated with survival outcome in subgroups of postmenopausal status (HR = 0.19; 95% CI = 0.04–0.90; p= 0.016), node negative status (HR = 0.12; 95% CI = 0.01–1.04; p = 0.026), and tumors larger than 2cm (HR = 0.21; 95% CI = 0.05–0.81; p = 0.021). This four-biomarker signature was significantly associated with TNBC as an independent prognostic factor for survival.
DOI: 10.6084/m9.figshare.11930346
title: Results of laboratory tests not accessed in Brazilian private laboratories

description: ABSTRACT Background: Laboratory medicine is an important part of the health care system and directly contributes to preventive actions, diagnostics, treatment, and management of diseases. The level and quality of laboratory resources utilization have been frequently questioned. A dissemination of conflicting data regarding the amount of laboratory tests not accessed by the requesting doctors or by the patients themselves is observed, although very often the sources and methodologies used to access these numbers are not properly clarified. Objective: The objective of this study was to obtain data on access to tests results performed in Brazilian private clinical analysis laboratories using the laboratory information system developed by SHIFT Consultoria e Sistemas (Consulting and Systems). Methods: The information was extracted from 81 laboratories, responsible for the performance of 93,240,651 tests, collected from 7,067,087 patients. Results: The total number of tests not accessed, considering all the regions, was 5,071,454, corresponding to a proportion of 5.4%. Due to the potential risks of adverse events or impacts on diagnostic and treatment management, including the economic impacts due to prolonged hospitalization time, the 17.9% proportion which was found to correspond to “not accessed” tests showing “abnormal” results. It is of particular concern, mainly if we observe that from these, 2.5% were related to “abnormal” test results processed by laboratories working in hospital units. Conclusion: Due to the relevance of the theme, Sociedade Brasileira de Patologia Clínica/Medicina Laboratorial (SBPC/ML), will keep encouraging the monitoring and utilization of adequate laboratory resources, in order to enable sustainable health care systems.
DOI: 10.6084/m9.figshare.11930346.v1
title: Results of laboratory tests not accessed in Brazilian private laboratories

description: ABSTRACT Background: Laboratory medicine is an important part of the health care system and directly contributes to preventive actions, diagnostics, treatment, and management of diseases. The level and quality of laboratory resources utilization have been frequently questioned. A dissemination of conflicting data regarding the amount of laboratory tests not accessed by the requesting doctors or by the patients themselves is observed, although very often the sources and methodologies used to access these numbers are not properly clarified. Objective: The objective of this study was to obtain data on access to tests results performed in Brazilian private clinical analysis laboratories using the laboratory information system developed by SHIFT Consultoria e Sistemas (Consulting and Systems). Methods: The information was extracted from 81 laboratories, responsible for the performance of 93,240,651 tests, collected from 7,067,087 patients. Results: The total number of tests not accessed, considering all the regions, was 5,071,454, corresponding to a proportion of 5.4%. Due to the potential risks of adverse events or impacts on diagnostic and treatment management, including the economic impacts due to prolonged hospitalization time, the 17.9% proportion which was found to correspond to “not accessed” tests showing “abnormal” results. It is of particular concern, mainly if we observe that from these, 2.5% were related to “abnormal” test results processed by laboratories working in hospital units. Conclusion: Due to the relevance of the theme, Sociedade Brasileira de Patologia Clínica/Medicina Laboratorial (SBPC/ML), will keep encouraging the monitoring and utilization of adequate laboratory resources, in order to enable sustainable health care systems.
DOI: 10.25739/vgjr-0a33
title: Rapid Automatic & Adaptive Model for Performance Prediction (RAAMP2) Dataset

description: The Multimodal Objective Sensing to Assess Individuals with Context (MOSAIC) project is an initiative funded by the Intelligence Advanced Research Projects Activity (IARPA) to improve the evaluative process in the workplace. To do so, researchers from Lockheed Martin's Advanced Technology Laboratories (LM ATL) and the University of Arizona (UA) conducted the Rapid Automatic & Adaptive Models for Performance Prediction (RAAMP2) study. Across two data collection studies, over 400 employees from a large company were equipped with a suite of both on-body and environmental sensors and completed daily surveys assessing well-being and job performance. Each study enrolled participants for eight weeks, with 50 individuals participating in both studies.
DOI: 10.6084/m9.figshare.11930337
title: BETWEEN DIVERSITY AND ANTAGONISM: ARTICULATORY PRACTICES OF LGBT DISCURSIVENESS IN THE BRAZILIAN MINISTRY OF CULTURE

description: This work focuses on a set of programs, actions, and institutional mechanisms of the Brazilian Ministry of Culture (MinC) that began to contemplate the LGBT community during the governments of Lula and Dilma. The study intended to understand the institutionalization of the cultural agendas of the LGBT movement at the federal level. We analyze MinC documents and public testimonies of agents of this universe using the support of Laclau and Mouffe’s Theory of Discourse (TD), a perspective according to which hegemony operates in a movement of negotiation between contradictory discourses, aiming to establish relations of order and social agglutination. We hypothesize that the MinC actions, especially the LGBT culture public announcements, sought to manage the conflicts between minority and hegemonic values in Brazilian society. The sexual and cultural differences embraced by the LGBT movement poses antagonisms that would have been neutralized by the liberal discourse of diversity.