cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.5791884
title: Development of microsatellite loci for Cryptocarya mandioccana Meisner (Lauraceae) and their genotyping success in different tissues

description: ABSTRACT Nine polymorphic microsatellite loci were isolated and characterized for Cryptocarya mandioccana Meisner, a tree from the Atlantic Rainforest with seeds dispersed by large animals. The loci were characterized using 48 individuals from two populations and their genotyping success tested in four tissues: leaves from adults and seedlings, and two diaspore maternal tissues. Maternity analyses were also performed on diaspores and leaves from nine adult trees. The number of alleles per locus ranged from nine to 15 and the observed and expected heterozygosities ranged from 0.214 to 0.864 and 0.745 to 0.892, respectively. The loci genotyping success did not significantly differ between tissues and varied from 56 to 96%. The microsatellites showed enough polymorphism to assign the nine adult trees to their diaspores. The successful genotyping in all tissues and identification of mother trees show that the microsatellites are suitable for studies such as spatial genetic structure and maternity analyses.
DOI: 10.6084/m9.figshare.5791884.v1
title: Development of microsatellite loci for Cryptocarya mandioccana Meisner (Lauraceae) and their genotyping success in different tissues

description: ABSTRACT Nine polymorphic microsatellite loci were isolated and characterized for Cryptocarya mandioccana Meisner, a tree from the Atlantic Rainforest with seeds dispersed by large animals. The loci were characterized using 48 individuals from two populations and their genotyping success tested in four tissues: leaves from adults and seedlings, and two diaspore maternal tissues. Maternity analyses were also performed on diaspores and leaves from nine adult trees. The number of alleles per locus ranged from nine to 15 and the observed and expected heterozygosities ranged from 0.214 to 0.864 and 0.745 to 0.892, respectively. The loci genotyping success did not significantly differ between tissues and varied from 56 to 96%. The microsatellites showed enough polymorphism to assign the nine adult trees to their diaspores. The successful genotyping in all tissues and identification of mother trees show that the microsatellites are suitable for studies such as spatial genetic structure and maternity analyses.
DOI: 10.6084/m9.figshare.5791881
title: Hydrogen sulfide: a new endogenous player in an old mechanism of plant tolerance to high salinity

description: ABSTRACT High salinity affects plants due to stimulation of osmotic stress. Cell signaling triggered by nitric oxide (NO) and hydrogen sulfide (H2S) activates a cascade of biochemical events that culminate in plant tolerance to abiotic and biotic stresses. For instance, the NO/H2S-stimulated biochemical events that occur in plants during response to high salinity include the control of reactive oxygen species, activation of antioxidant system, accumulation of osmoprotectants in cytosol, induction of K+ uptake and Na+ cell extrusion or its vacuolar compartmentation among others. This review is a compilation of what we have learned in the last 10 years about NO participation during cell signaling in response to high salinity as well as the role of H2S, a new player in the mechanism of plant tolerance to salt stress. The main sources of NO and H2S in plant cells is also discussed together with the evidence of interplay between both signaling molecules during response to stress.
DOI: 10.3886/e120861v1
title: Significant Executive Orders and Proclamations 1861-2016

description: This project contains a list of executive orders and proclamations that were mentioned in The New York Times from 1861-2016 (Excel files contains non-ceremonial and ceremonial directives, ceremonial directives are highlighted yellow). See Unilateral Politics in the Traditional Era: Significant Executive Orders and Proclamations, 1861–1944 (Williams 2020) for a detailed explanation on how the data was collected. Also contains data (and codebook) used in the statistical analysis in Williams 2020 (Excel and Stata files).
DOI: 10.3886/e113090v1-43785
title: Replication data for: Virtual Classrooms: How Online College Courses Affect Student Success

description: Online college courses are a rapidly expanding feature of higher education, yet little research identifies their effects relative to traditional in-person classes. Using an instrumental variables approach, we find that taking a course online, instead of in-person, reduces student success and progress in college. Grades are lower both for the course taken online and in future courses. Students are less likely to remain enrolled at the university. These estimates are local average treatment effects for students with access to both online and in-person options; for other students, online classes may be the only option for accessing college-level courses.
DOI: 10.6084/m9.figshare.5791881.v1
title: Hydrogen sulfide: a new endogenous player in an old mechanism of plant tolerance to high salinity

description: ABSTRACT High salinity affects plants due to stimulation of osmotic stress. Cell signaling triggered by nitric oxide (NO) and hydrogen sulfide (H2S) activates a cascade of biochemical events that culminate in plant tolerance to abiotic and biotic stresses. For instance, the NO/H2S-stimulated biochemical events that occur in plants during response to high salinity include the control of reactive oxygen species, activation of antioxidant system, accumulation of osmoprotectants in cytosol, induction of K+ uptake and Na+ cell extrusion or its vacuolar compartmentation among others. This review is a compilation of what we have learned in the last 10 years about NO participation during cell signaling in response to high salinity as well as the role of H2S, a new player in the mechanism of plant tolerance to salt stress. The main sources of NO and H2S in plant cells is also discussed together with the evidence of interplay between both signaling molecules during response to stress.
DOI: 10.6084/m9.figshare.5791878
title: Canine insulinoma: case reports

description: ABSTRACT Insulinoma is a tumor of the β cells of the pancreas, which have the function to produce and secrete insulin and are usually malignant in dogs. This paper describes the diagnosis and therapeutic management of three cases of insulinoma. The clinical signs reported animals varied according to the severity and duration of hypoglycemia. The presumptive diagnosis was based on clinical signs and serum insulin dosage at the time of hypoglycemia and more intense, the definitive diagnosis was made by histopathological examination in three of the reported cases. The treatment was varied according to the severity of clinical signs.
DOI: 10.6084/m9.figshare.5791878.v1
title: Canine insulinoma: case reports

description: ABSTRACT Insulinoma is a tumor of the β cells of the pancreas, which have the function to produce and secrete insulin and are usually malignant in dogs. This paper describes the diagnosis and therapeutic management of three cases of insulinoma. The clinical signs reported animals varied according to the severity and duration of hypoglycemia. The presumptive diagnosis was based on clinical signs and serum insulin dosage at the time of hypoglycemia and more intense, the definitive diagnosis was made by histopathological examination in three of the reported cases. The treatment was varied according to the severity of clinical signs.
DOI: 10.6084/m9.figshare.5791875
title: INTRA-REGIONAL TRADE IN SERVICES IN SOUTH AMERICA: AN INPUT-OUTPUT APPROACH

description: ABSTRACT Purpose: The growing importance of the services sector is not only a fact in developed countries but is also visible in the South American subcontinent, in terms of Gross Domestic Product share, employment and foreign trade. Taking a closer look at the role of services, the present article analyzes the main linkages in trade in services in the two largest South American economies, namely, Brazil and Argentina. Originality/Value: The recently available South American input-output table provided by United Nations Economic Commission for Latin America and the Caribbean (UN ECLAC). It is a ten-region open model that is used to study two important aspects of trade in services for the two selected economies: first, testing whether the participation of services in total trade increases when the calculation is specified in terms of value added; and second, assessing the role of services in promoting the countries’ exports. Design/methodology/approach: The present research helps to better understand the position of the region as provider and demander of intra-regional services. However, the scarcity of statistics related to trade in services is a limitation that must be solved. The data was obtained from the South American input-output table. A single-regional input-output model was generated for Argentina and Brazil for 2005. Findings: The main findings of the article include that 1. in both economies, the participation of services in foreign trade is higher in terms of value added than under conventional gross trade data, and 2. Argentina is more integrated with the region than Brazil in terms of intra-regional imported services in its exports.
DOI: 10.6084/m9.figshare.5791875.v1
title: INTRA-REGIONAL TRADE IN SERVICES IN SOUTH AMERICA: AN INPUT-OUTPUT APPROACH

description: ABSTRACT Purpose: The growing importance of the services sector is not only a fact in developed countries but is also visible in the South American subcontinent, in terms of Gross Domestic Product share, employment and foreign trade. Taking a closer look at the role of services, the present article analyzes the main linkages in trade in services in the two largest South American economies, namely, Brazil and Argentina. Originality/Value: The recently available South American input-output table provided by United Nations Economic Commission for Latin America and the Caribbean (UN ECLAC). It is a ten-region open model that is used to study two important aspects of trade in services for the two selected economies: first, testing whether the participation of services in total trade increases when the calculation is specified in terms of value added; and second, assessing the role of services in promoting the countries’ exports. Design/methodology/approach: The present research helps to better understand the position of the region as provider and demander of intra-regional services. However, the scarcity of statistics related to trade in services is a limitation that must be solved. The data was obtained from the South American input-output table. A single-regional input-output model was generated for Argentina and Brazil for 2005. Findings: The main findings of the article include that 1. in both economies, the participation of services in foreign trade is higher in terms of value added than under conventional gross trade data, and 2. Argentina is more integrated with the region than Brazil in terms of intra-regional imported services in its exports.
DOI: 10.6084/m9.figshare.5791872
title: The use of biosimilar medicines in oncology - position statement of the Brazilian Society of Clinical Oncology (SBOC)

description: A biosimilar is a biologic product that is similar to a reference biopharmaceutical product, the manufacturing process of which hinders the ability to identically replicate the structure of the original product, and therefore, it cannot be described as an absolute equivalent of the original medication. The currently available technology does not allow for an accurate copy of complex molecules, but it does allow the replication of similar molecules with the same activity. As biosimilars are about to be introduced in oncology practice, these must be evaluated through evidence-based medicine. This manuscript is a position paper, where the Brazilian Society of Clinical Oncology (SBOC) aims to describe pertinent issues regarding the approval and use of biosimilars in oncology. As a working group on behalf of SBOC, we discuss aspects related to definition, labeling/nomenclature, extrapolation, interchangeability, switching, automatic substitution, clinical standards on safety and efficacy, and the potential impact on financial burden in healthcare. We take a stand in favor of the introduction of biosimilars, as they offer a viable, safe, and cost-effective alternative to the biopharmaceutical products currently used in cancer. We hope this document can provide valuable information to support therapeutic decisions that maximize the clinical benefit for the thousands of cancer patients in Brazil and can contribute to expedite the introduction of this new drug class in clinical practice. We expect the conveyed information to serve as a basis for further discussion in Latin America, this being the first position paper issued by a Latin American Oncology Society.
DOI: 10.6084/m9.figshare.5791872.v1
title: The use of biosimilar medicines in oncology - position statement of the Brazilian Society of Clinical Oncology (SBOC)

description: A biosimilar is a biologic product that is similar to a reference biopharmaceutical product, the manufacturing process of which hinders the ability to identically replicate the structure of the original product, and therefore, it cannot be described as an absolute equivalent of the original medication. The currently available technology does not allow for an accurate copy of complex molecules, but it does allow the replication of similar molecules with the same activity. As biosimilars are about to be introduced in oncology practice, these must be evaluated through evidence-based medicine. This manuscript is a position paper, where the Brazilian Society of Clinical Oncology (SBOC) aims to describe pertinent issues regarding the approval and use of biosimilars in oncology. As a working group on behalf of SBOC, we discuss aspects related to definition, labeling/nomenclature, extrapolation, interchangeability, switching, automatic substitution, clinical standards on safety and efficacy, and the potential impact on financial burden in healthcare. We take a stand in favor of the introduction of biosimilars, as they offer a viable, safe, and cost-effective alternative to the biopharmaceutical products currently used in cancer. We hope this document can provide valuable information to support therapeutic decisions that maximize the clinical benefit for the thousands of cancer patients in Brazil and can contribute to expedite the introduction of this new drug class in clinical practice. We expect the conveyed information to serve as a basis for further discussion in Latin America, this being the first position paper issued by a Latin American Oncology Society.
DOI: 10.6084/m9.figshare.5791869
title: Contradictions in the action of the volunteer in civil society organizations: theoretical essay in the light of French pragmatic sociology

description: Abstract Volunteering is a growing social phenomenon in the current context and is presented as an alternative to the logic of capitalism in the management of civil society organizations. However, it is possible that there are contradictions in the action of the volunteer, whose human action may be mediated by behavioral factors underlying apparent behavior, not always considered noble, such as egoism. This theoretical essay aims to understand what is behind human action in the behavior of volunteers of civil society organizations (CSOs). Therefore, the theoretical arguments were built by pragmatic sociology, which seeks to find reasons for acting through symbolic mediations, to the detriment of behavioral psychology. It is argued that volunteers are endowed with rational and justifiable behavior by three pragmatic regimes developed by Laurent Thévenot and by the complementary concepts of Frédéric Vandenberghe; both argue that human actions are justifiable. The arguments presented theoretically, confirm that the behavioral factors of the volunteers, produce effects on the results of the CSOs. These effects include the low degree of involvement of the volunteers with the organizations, since the justifications for acting can be centered on world such as “fame” and “mercantile”, contributing to generate uneasiness among researchers about the possible inference of what lies behind human action.
DOI: 10.6084/m9.figshare.5791869.v1
title: Contradictions in the action of the volunteer in civil society organizations: theoretical essay in the light of French pragmatic sociology

description: Abstract Volunteering is a growing social phenomenon in the current context and is presented as an alternative to the logic of capitalism in the management of civil society organizations. However, it is possible that there are contradictions in the action of the volunteer, whose human action may be mediated by behavioral factors underlying apparent behavior, not always considered noble, such as egoism. This theoretical essay aims to understand what is behind human action in the behavior of volunteers of civil society organizations (CSOs). Therefore, the theoretical arguments were built by pragmatic sociology, which seeks to find reasons for acting through symbolic mediations, to the detriment of behavioral psychology. It is argued that volunteers are endowed with rational and justifiable behavior by three pragmatic regimes developed by Laurent Thévenot and by the complementary concepts of Frédéric Vandenberghe; both argue that human actions are justifiable. The arguments presented theoretically, confirm that the behavioral factors of the volunteers, produce effects on the results of the CSOs. These effects include the low degree of involvement of the volunteers with the organizations, since the justifications for acting can be centered on world such as “fame” and “mercantile”, contributing to generate uneasiness among researchers about the possible inference of what lies behind human action.
DOI: 10.6084/m9.figshare.5791857
title: Human leptospirosis in the Federal District, Brazil, 2011-2015: eco-epidemiological characterization

description: Abstract INTRODUCTION: Leptospirosis is an infectious disease that affects more than 5,000 people per year in Brazil. The Federal District (FD) lacks epidemiological studies of human leptospirosis and presents concerning rates of this disease, especially considering its lethality. METHODS: Seventy-nine autochthonous human cases of leptospirosis between 2011 and 2015 were analyzed, with the probable infection location serving as a basis for the collection and analysis of the environmental and epidemiological variables. RESULTS: The incidence of the disease ranged from 0.68-13.39 per 100,000 inhabitants in 21 of the 31 administrative regions that compose the FD. The local profile of human leptospirosis was predominantly associated with urban areas during the rainy season, population access to the sewage network, the treated water network, and the public garbage collection service. The vast majority of cases had a strong association with synanthropic rodents at the infection sites. CONCLUSIONS: In order to prevent and control potentially lethal human leptospirosis infection, the eco-epidemiological characterization of this disease is a valuable tool for public policies of prevention, control, and surveillance. In addition to population awareness, the systematized control of synanthropic rodents could be the main health action to reduce the incidence of this disease in the FD.
DOI: 10.6084/m9.figshare.5791857.v1
title: Human leptospirosis in the Federal District, Brazil, 2011-2015: eco-epidemiological characterization

description: Abstract INTRODUCTION: Leptospirosis is an infectious disease that affects more than 5,000 people per year in Brazil. The Federal District (FD) lacks epidemiological studies of human leptospirosis and presents concerning rates of this disease, especially considering its lethality. METHODS: Seventy-nine autochthonous human cases of leptospirosis between 2011 and 2015 were analyzed, with the probable infection location serving as a basis for the collection and analysis of the environmental and epidemiological variables. RESULTS: The incidence of the disease ranged from 0.68-13.39 per 100,000 inhabitants in 21 of the 31 administrative regions that compose the FD. The local profile of human leptospirosis was predominantly associated with urban areas during the rainy season, population access to the sewage network, the treated water network, and the public garbage collection service. The vast majority of cases had a strong association with synanthropic rodents at the infection sites. CONCLUSIONS: In order to prevent and control potentially lethal human leptospirosis infection, the eco-epidemiological characterization of this disease is a valuable tool for public policies of prevention, control, and surveillance. In addition to population awareness, the systematized control of synanthropic rodents could be the main health action to reduce the incidence of this disease in the FD.
DOI: 10.6084/m9.figshare.5791854
title: Correlations of microstructure and mechanical properties of the ternary Sn-9wt%Zn-2wt%Cu solder alloy

description: The microstructure length-scales (dendritic and eutectic), morphologies and tensile properties of a ternary Sn-9wt.%Zn-2wt.%Cu alloy are compared with those of a binary eutectic Sn-9wt.%Zn alloy. The following experimental/analytical steps were performed: transient directional solidification experiments of the Sn-9wt.%Zn-2wt.%Cu alloy; measurements of secondary dendrite arm (λ2) and interphase spacing (λ); morphology of the eutectic α-Zn phase; determination of thermal parameters such as cooling rate (ṪL) and their evolutions during solidification; and, finally, interrelations of microstructure vs. tensile properties. The addition of 2wt.%Cu causes significant refinement of the eutectic structure. Hall-Petch type experimental expressions outlined the variations of strength and ductility with both λ2 and λ. Very fine Zn globules and needles forming the eutectic in the ternary alloy seems to cause a reversal on ductility behavior, as compared to the tendency observed for the binary Sn-9wt.%Zn alloy. Here, for the ternary Sn-9wt.%Zn-2wt.%Cu alloy ductility increases with decreasing interphase spacing.
DOI: 10.6084/m9.figshare.5791854.v1
title: Correlations of microstructure and mechanical properties of the ternary Sn-9wt%Zn-2wt%Cu solder alloy

description: The microstructure length-scales (dendritic and eutectic), morphologies and tensile properties of a ternary Sn-9wt.%Zn-2wt.%Cu alloy are compared with those of a binary eutectic Sn-9wt.%Zn alloy. The following experimental/analytical steps were performed: transient directional solidification experiments of the Sn-9wt.%Zn-2wt.%Cu alloy; measurements of secondary dendrite arm (λ2) and interphase spacing (λ); morphology of the eutectic α-Zn phase; determination of thermal parameters such as cooling rate (ṪL) and their evolutions during solidification; and, finally, interrelations of microstructure vs. tensile properties. The addition of 2wt.%Cu causes significant refinement of the eutectic structure. Hall-Petch type experimental expressions outlined the variations of strength and ductility with both λ2 and λ. Very fine Zn globules and needles forming the eutectic in the ternary alloy seems to cause a reversal on ductility behavior, as compared to the tendency observed for the binary Sn-9wt.%Zn alloy. Here, for the ternary Sn-9wt.%Zn-2wt.%Cu alloy ductility increases with decreasing interphase spacing.