cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q2h41wg2
title: BindingDB Entry 50017333: Novel Bcl-2 Inhibitors Selectively Disrupt the Autophagy-Specific Bcl-2-Beclin 1 Protein-Protein Interaction.

description: Small molecule binding data for protein Apoptosis regulator Bcl-2, Uniprot P10415
DOI: 10.7270/q2mw2n6g
title: BindingDB Entry 50017332: Biological Effects of Modifications of the Englerin A Glycolate.

description: Small molecule binding data for protein Short transient receptor potential channel 5, Uniprot Q9UL62
DOI: 10.7270/q2rn3cxs
title: BindingDB Entry 50017330: Novel 3-Aminopyrrolidine and Piperidine Macrocyclic Orexin Receptor Agonists for Treating Sleep Disorders.

description: Small molecule binding data for protein Orexin receptor type 2, Uniprot O43614
DOI: 10.7270/q2wd44nh
title: BindingDB Entry 50017329: Bisubstrate Inhibitors of Severe Acute Respiratory Syndrome Coronavirus-2 Nsp14 Methyltransferase.

description: Small molecule binding data for protein Replicase polyprotein 1ab, Uniprot P0DTD1
DOI: 10.7270/q2154n3c
title: BindingDB Entry 50017324: Discovery of Insulin/GLP-1/Glucagon Triagonists for the Treatment of Diabetes and Obesity.

description: Small molecule binding data for protein Glucagon receptor and Glucagon-like peptide 1 receptor, Uniprot P43220 and P47871
DOI: 10.7270/q24t6pfh
title: BindingDB Entry 50017323: Discovery and Optimization of Triazolopyrimidinone Derivatives as Selective NLRP3 Inflammasome Inhibitors.

description: Small molecule binding data for protein NACHT, LRR and PYD domains-containing protein 3, Uniprot Q96P20
DOI: 10.7270/q28k7f4s
title: BindingDB Entry 50017322: Discovery of Novel 2-Carbamoyl Morpholine Derivatives as Highly Potent and Orally Active Direct Renin Inhibitors.

description: Small molecule binding data for protein Renin, Uniprot P00797
DOI: 10.7270/q2db85x0
title: BindingDB Entry 50017318: Discovery of Tenapanor: A First-in-Class Minimally Systemic Inhibitor of Intestinal Na

description: Small molecule binding data for protein Sodium/hydrogen exchanger 3, Uniprot P26433 and P48764
DOI: 10.7270/q2j38xnb
title: BindingDB Entry 50017313: Discovery and Characterization of a Novel Series of Chloropyrimidines as Covalent Inhibitors of the Kinase MSK1.

description: Small molecule binding data for protein Ribosomal protein S6 kinase alpha-4 and Ribosomal protein S6 kinase alpha-5, Uniprot O75582 and O75676
DOI: 10.7270/q2nv9pb9
title: BindingDB Entry 50017311: Design, Synthesis, and Biological Activity of New CB2 Receptor Ligands: from Orthosteric and Allosteric Modulators to Dualsteric/Bitopic Ligands.

description: Small molecule binding data for protein Cannabinoid receptor 1 and Cannabinoid receptor 2, Uniprot P21554 and P34972
DOI: 10.7270/q2sn0f14
title: BindingDB Entry 50017310: Discovery of Novel Phosphoinositide-3-Kinase α Inhibitors with High Selectivity, Excellent Bioavailability, and Long-Acting Efficacy for Gastric Cancer.

description: Small molecule binding data for protein Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform, and Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, Uniprot O00329, P42336, P42338, and P48736
DOI: 10.7270/q2xd15q0
title: BindingDB Entry 50017309: Design and Discovery of MRTX0902, a Potent, Selective, Brain-Penetrant, and Orally Bioavailable Inhibitor of the SOS1:KRAS Protein-Protein Interaction.

description: Small molecule binding data for protein Cytochrome P450 3A4, Epidermal growth factor receptor, and Son of sevenless homolog 1, Uniprot P00533, P08684, and Q07889
DOI: 10.7270/q2222zvg
title: BindingDB Entry 50017308: Discovery of Selective Nanomolar Inhibitors for Insulin-Regulated Aminopeptidase Based on α-Hydroxy-β-amino Acid Derivatives of Bestatin.

description: Small molecule binding data for protein Endoplasmic reticulum aminopeptidase 1, Endoplasmic reticulum aminopeptidase 2, and Interleukin-1 receptor antagonist protein, Uniprot P18510, Q6P179, and Q9NZ08
DOI: 10.7270/q25t3qjf
title: BindingDB Entry 50017307: Identification of Human Alanine-Glyoxylate Aminotransferase Ligands as Pharmacological Chaperones for Variants Associated with Primary Hyperoxaluria Type 1.

description: Small molecule binding data for protein Alanine--glyoxylate aminotransferase, Uniprot P21549
DOI: 10.7270/q29k4g9m
title: BindingDB Entry 50017306: Discovery and Optimization of a Synthetic Class of Nectin-4-Targeted CD137 Agonists for Immuno-oncology.

description: Small molecule binding data for protein Nectin-4 and Tumor necrosis factor receptor superfamily member 9, Uniprot Q07011 and Q96NY8
DOI: 10.7270/q2fb571b
title: BindingDB Entry 50017305: Design, Synthesis, and Characterization of [

description: Small molecule binding data for protein Metabotropic glutamate receptor 1, Metabotropic glutamate receptor 2, Metabotropic glutamate receptor 3, Metabotropic glutamate receptor 4, Metabotropic glutamate receptor 5, Metabotropic glutamate receptor 6, and Metabotropic glutamate receptor 8, Uniprot O00222, O15303, P41594, Q13255, Q14416, Q14832, and Q14833
DOI: 10.7270/q2k35zr8
title: BindingDB Entry 50017303: Discovery of (

description: Small molecule binding data for protein Androgen receptor, Bile acid receptor, Estrogen receptor, Glucocorticoid receptor, Mineralocorticoid receptor, Oxysterols receptor LXR-alpha, Oxysterols receptor LXR-beta, Peroxisome proliferator-activated receptor alpha, Peroxisome proliferator-activated receptor delta, Peroxisome proliferator-activated receptor gamma, Progesterone receptor, Retinoic acid receptor RXR-alpha, Retinoic acid receptor RXR-beta, Retinoic acid receptor alpha, Retinoic acid receptor beta, Thyroid hormone receptor alpha, and Thyroid hormone receptor beta, Uniprot P03372, P04150, P06401, P08235, P10275, P10276, P10826, P10827, P10828, P19793, P28702, P37231, P55055, Q03181, Q07869, Q13133, and Q96RI1
DOI: 10.7270/q2pv6qf7
title: BindingDB Entry 50017301: Design, Synthesis, and Structure-Activity Relationship Studies of Bisamide Derivatives of Amphotericin B with Potent Efficacy and Low Toxicity.

description: Small molecule binding data for protein Cytochrome P450 1A2, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A4, and Potassium voltage-gated channel subfamily H member 2, Uniprot P05177, P08684, P10635, P11712, P33261, and Q12809
DOI: 10.7270/q2tm7g5z
title: BindingDB Entry 50017299: -Acylamino Saccharin as an Emerging Cysteine-Directed Covalent Warhead and Its Application in the Identification of Novel FBPase Inhibitors toward Glucose Reduction.

description: Small molecule binding data for protein Fructose-1,6-bisphosphatase 1, Uniprot P09467
DOI: 10.7270/q2z89hgz
title: BindingDB Entry 50017296: Structure-Based Design, Optimization, and Development of [

description: Small molecule binding data for protein Cannabinoid receptor 1 and Cannabinoid receptor 2, Uniprot P21554, P34972, and Q9QZN9
DOI: 10.7270/q23200xb
title: BindingDB Entry 50017295: Innovative Non-PrP-Targeted Drug Strategy Designed to Enhance Prion Clearance.

description: Small molecule binding data for protein Major prion protein and Serine protease inhibitor A3N, Uniprot P04925 and Q91WP6
DOI: 10.7270/q26t0rq8
title: BindingDB Entry 50017294: Next-Generation Diprovocims with Potent Human and Murine TLR1/TLR2 Agonist Activity That Activate the Innate and Adaptive Immune Response.

description: Small molecule binding data for protein Toll-like receptor 1 and Toll-like receptor 2, Uniprot Q15399 and Q9QUN7
DOI: 10.7270/q2bk1hf0
title: BindingDB Entry 50017292: Optimization of TEAD P-Site Binding Fragment Hit into In Vivo Active Lead

description: Small molecule binding data for protein Cytochrome P450 1A2, Cytochrome P450 2B6, Cytochrome P450 2C19, Cytochrome P450 2C8, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A4, Transcriptional enhancer factor TEF-1, Transcriptional enhancer factor TEF-3, Transcriptional enhancer factor TEF-4, and Transcriptional enhancer factor TEF-5, Uniprot P05177, P08684, P10632, P10635, P11712, P20813, P28347, P33261, Q15561, Q15562, and Q99594
DOI: 10.7270/q2gb2848
title: BindingDB Entry 50017291: Orally Bioavailable Enzymatic Inhibitor of CD38,

description: Small molecule binding data for protein ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, Uniprot P28907, P56528, and Q64244
DOI: 10.7270/q2m330t4
title: BindingDB Entry 50017290: Novel Hybrids of 3-Substituted Coumarin and Phenylsulfonylfuroxan as Potent Antitumor Agents with Collateral Sensitivity against MCF-7/ADR.

description: Small molecule binding data for protein Potassium voltage-gated channel subfamily H member 2, Uniprot Q12809
DOI: 10.7270/q2qr5264
title: BindingDB Entry 50017288: Cosolvent Sites-Based Discovery of

description: Small molecule binding data for protein Serine/threonine-protein kinase PknG, Uniprot P9WI73
DOI: 10.7270/q2vh5swm
title: BindingDB Entry 50017287: Discovery of Two Novel Antiplatelet Clinical Candidates (BMS-986120 and BMS-986141) That Antagonize Protease-Activated Receptor 4.

description: Small molecule binding data for protein Cytochrome P450 2B6, Cytochrome P450 2C19, Cytochrome P450 2C8, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A4, Nuclear receptor subfamily 1 group I member 2, and Proteinase-activated receptor 4, Uniprot O75469, P08684, P10632, P10635, P11712, P20813, P33261, and Q96RI0
DOI: 10.7270/q20869bv
title: BindingDB Entry 50017285: Design, Synthesis, and Optimization of Macrocyclic Peptides as Species-Selective Antimalaria Proteasome Inhibitors.

description: Small molecule binding data for protein Proteasome subunit beta type-5 and Proteasome subunit beta type-8, Uniprot P28062 and P28074
DOI: 10.7270/q2417231
title: BindingDB Entry 50017281: Discovery of Novel Benzo[4,5]imidazo[1,2-

description: Small molecule binding data for protein Adenosine receptor A1, Adenosine receptor A2a, Adenosine receptor A2b, and Adenosine receptor A3, Uniprot P0DMS8, P29274, P29275, and P30542
DOI: 10.7270/q27s7stn
title: BindingDB Entry 50017279: Discovery of BMS-986339, a Pharmacologically Differentiated Farnesoid X Receptor Agonist for the Treatment of Nonalcoholic Steatohepatitis.

description: Small molecule binding data for protein Bile acid receptor, Bile salt export pump, Cytochrome P450 2C19, Cytochrome P450 2C8, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A4, Nuclear receptor subfamily 1 group I member 2, Potassium voltage-gated channel subfamily H member 2, RNA-binding protein FXR2, Solute carrier organic anion transporter family member 1B3, and UDP-glucuronosyltransferase 1A1, Uniprot O75469, O95342, P08684, P10632, P10635, P11712, P22309, P33261, P51116, Q12809, Q60641, Q96RI1, and Q9NPD5
DOI: 10.7270/q2cj8jjc
title: BindingDB Entry 50017277: Multitarget, Selective Compound Design Yields Potent Inhibitors of a Kinetoplastid Pteridine Reductase 1.

description: Small molecule binding data for protein Bifunctional dihydrofolate reductase-thymidylate synthase, Dihydrofolate reductase, Pteridine reductase 1, and Pteridine reductase, putative, Uniprot P00374, P07382, Q01782, Q581W1, and Q582G3
DOI: 10.7270/q2h9997n
title: BindingDB Entry 50017276: Glenthmycins A-M: Macrocyclic Spirotetronate Polyketide Antibacterials from the Australian Pasture Plant-Derived

description: Small molecule binding data for protein Cholesterol side-chain cleavage enzyme, mitochondrial, Uniprot P14137
DOI: 10.7270/q2n01bm3
title: BindingDB Entry 50017275: Synthesis and characterization of an orally bioavailable small molecule agonist of the apelin receptor.

description: Small molecule binding data for protein Apelin receptor, Uniprot P35414
DOI: 10.7270/q2rr2392
title: BindingDB Entry 50017274: Benzodiazepine Derivatives as Potent Vasopressin V

description: Small molecule binding data for protein Vasopressin V1a receptor and Vasopressin V2 receptor, Uniprot P30518 and P37288
DOI: 10.7270/q2wh2v1d
title: BindingDB Entry 50017273: 2-Alkyl substituted benzimidazoles as a new class of selective AT2 receptor ligands.

description: Small molecule binding data for protein Type-1 angiotensin II receptor and Type-2 angiotensin II receptor, Uniprot P30556 and P50052
DOI: 10.7270/q2183bkk
title: BindingDB Entry 50017272: Design, synthesis and structure-activity relationship of 4-(1,1,1,3,3,3-hexafluoro-2-hydroxyisoprop-2-yl)phenylsilane derivatives as liver X receptor agonists.

description: Small molecule binding data for protein Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta, Uniprot P55055 and Q13133
DOI: 10.7270/q2514399
title: BindingDB Entry 50017267: Discovery of 2,4-diarylaminopyrimidine derivatives bearing dithiocarbamate moiety as novel ALK inhibitors.

description: Small molecule binding data for protein ALK tyrosine kinase receptor, Uniprot Q9UM73
DOI: 10.7270/q28s4v0w
title: BindingDB Entry 50017262: Design, synthesis, and evaluation of new vanin-1 inhibitors based on RR6.

description: Small molecule binding data for protein Pantetheinase, Uniprot O95497
DOI: 10.7270/q2dj5kpr
title: BindingDB Entry 50017260: Identification of novel indole derivatives as highly potent AMPK activators with anti-diabetic profiles.

description: Small molecule binding data for protein 5'-AMP-activated protein kinase subunit beta-1, 5'-AMP-activated protein kinase subunit beta-2, Cytochrome P450 1A2, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6, and Cytochrome P450 3A4, Uniprot O43741, P05177, P08684, P10635, P11712, P33261, and P80386
DOI: 10.7270/q2j67n05
title: BindingDB Entry 50017258: Phenotypic screen identifies FOXO inhibitor to counteract maturation and promote expansion of human iPS cell-derived cardiomyocytes.

description: Small molecule binding data for protein Forkhead box protein O1, Uniprot Q12778
DOI: 10.7270/q2nz8cpq
title: BindingDB Entry 50017256: Discovery of novel benzothiophene derivatives as potent and narrow spectrum inhibitors of DYRK1A and DYRK1B.

description: Small molecule binding data for protein Dual specificity tyrosine-phosphorylation-regulated kinase 1A, Dual specificity tyrosine-phosphorylation-regulated kinase 1B, and Serine/threonine-protein kinase PRP4 homolog, Uniprot Q13523, Q13627, and Q9Y463
DOI: 10.7270/q2sq94fw
title: BindingDB Entry 50017249: Design and synthesis of endocannabinoid enzyme inhibitors for ocular indications.

description: Small molecule binding data for protein Fatty-acid amide hydrolase 1 and Monoglyceride lipase, Uniprot O00519, O08914, and Q99685
DOI: 10.7270/q2xg9w6p
title: BindingDB Entry 50017246: Design, synthesis and conformation-activity relationship analysis of LNA/BNA-type 5'-O-aminoribosyluridine as MraY inhibitors.

description: Small molecule binding data for protein Phospho-N-acetylmuramoyl-pentapeptide-transferase, Uniprot P0C1R8
DOI: 10.7270/q2280cph
title: BindingDB Entry 50017245: Lead optimization of pyrido[2,3-d][1]benzazepin-6-one derivatives leading to the discovery of a potent, selective, and orally available human parathyroid hormone receptor 1 (hPTHR1) antagonist (DS69910557).

description: Small molecule binding data for protein Parathyroid hormone/parathyroid hormone-related peptide receptor, Uniprot Q03431
DOI: 10.7270/q26114d7
title: BindingDB Entry 50017244: In silico, synthesis and anticancer evaluation of benzamide tryptamine derivatives as novel eEF2K inhibitors.

description: Small molecule binding data for protein Eukaryotic elongation factor 2 kinase, Uniprot O00418
DOI: 10.7270/q29s1w3t
title: BindingDB Entry 50017239: A kind of HIV-1 protease inhibitors containing phenols with antiviral activity against DRV-resistant variants.

description: Small molecule binding data for protein Gag-Pol polyprotein [489-587], Uniprot P04585
DOI: 10.7270/q2ff3xdt
title: BindingDB Entry 50017237: Explorations of novel pyridine-pyrimidine hybrid phosphonate derivatives as aurora kinase inhibitors.

description: Small molecule binding data for protein Aurora kinase A and Aurora kinase B, Uniprot O14965 and Q96GD4
DOI: 10.7270/q2k64p33
title: BindingDB Entry 50017234: Clerodane Diterpenes from

description: Small molecule binding data for protein Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2, Uniprot P14867, P18507, and P47870
DOI: 10.7270/q2pz5dvj
title: BindingDB Entry 50017233: Discovery of 3, 6-disubstituted isobenzofuran-1(3H)-ones as novel inhibitors of monoamine oxidases.

description: Small molecule binding data for protein Amine oxidase [flavin-containing] A and Amine oxidase [flavin-containing] B, Uniprot P19643 and P21396
DOI: 10.7270/q2tq65mq
title: BindingDB Entry 50017232: Identification of Antithrombotic Natural Products Targeting the Major Substrate Binding Pocket of Protein Disulfide Isomerase.

description: Small molecule binding data for protein Protein disulfide-isomerase, Uniprot P07237
DOI: 10.7270/q2zg6x9m
title: BindingDB Entry 50017231: Piezo-Type Mechanosensitive Ion Channel Component 1 (Piezo1): A Promising Therapeutic Target and Its Modulators.

description: Small molecule binding data for protein Piezo-type mechanosensitive ion channel component 1, Uniprot E2JF22 and Q92508
DOI: 10.7270/q2377dsw
title: BindingDB Entry 50017229: Discovery of benzo[d]oxazol-2(3H)-one derivatives as a new class of TNIK inhibitors for the treatment of colorectal cancer.

description: Small molecule binding data for protein TRAF2 and NCK-interacting protein kinase, Uniprot Q9UKE5
DOI: 10.7270/q27085g5
title: BindingDB Entry 50017227: The evaluation of N-propargylamine-2-aminotetralin as an inhibitor of monoamine oxidase.

description: Small molecule binding data for protein Amine oxidase [flavin-containing] A and Amine oxidase [flavin-containing] B, Uniprot P19643, P21396, P21397, and P27338
DOI: 10.7270/q2bp06v9
title: BindingDB Entry 50017226: Discovery of (R)-(3-fluoropyrrolidin-1-yl)(6-((5-(trifluoromethyl)pyridin-2-yl)oxy)quinolin-2-yl)methanone (ABBV-318) and analogs as small molecule Na

description: Small molecule binding data for protein Potassium voltage-gated channel subfamily H member 2, Sodium channel protein type 2 subunit alpha, Sodium channel protein type 5 subunit alpha, Sodium channel protein type 7 subunit alpha, and Sodium channel protein type 8 subunit alpha, Uniprot Q01118, Q12809, Q14524, Q99250, and Q9UQD0
DOI: 10.7270/q2gf0zj6
title: BindingDB Entry 50017223: Discovery and preclinical profile of LX-039, a novel indole-based oral selective estrogen receptor degrader (SERD).

description: Small molecule binding data for protein Cytochrome P450 1A2, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6, and Cytochrome P450 3A4, Uniprot P05177, P08684, P10635, P11712, and P33261
DOI: 10.7270/q2m61q9c
title: BindingDB Entry 50017222: Stapled peptides as scaffolds for developing radiotracers for intracellular targets: Preliminary evaluation of a radioiodinated MDM2-binding stapled peptide in the SJSA-1 osteosarcoma model.

description: Small molecule binding data for protein E3 ubiquitin-protein ligase Mdm2, Uniprot Q00987
DOI: 10.7270/q2qz2g1s
title: BindingDB Entry 50017218: Modular synthesis of 2,4-diaminoanilines as CNS drug-like non-covalent inhibitors of asparagine endopeptidase.

description: Small molecule binding data for protein Legumain, Uniprot Q99538
DOI: 10.7270/q2vq36r3
title: BindingDB Entry 50017217: Identification of Aloe-derived natural products as prospective lead scaffolds for SARS-CoV-2 main protease (M

description: Small molecule binding data for protein Replicase polyprotein 1ab, Uniprot P0DTD1
DOI: 10.7270/q20g3q7d
title: BindingDB Entry 50017213: Discovery and preclinical evaluations of WX-0593, a novel ALK inhibitor targeting crizotinib-resistant mutations.

description: Small molecule binding data for protein ALK tyrosine kinase receptor and Epidermal growth factor receptor, Uniprot P00533 and Q9UM73
DOI: 10.7270/q2474fx8
title: BindingDB Entry 50017210: Optimisation of momelotinib with improved potency and efficacy as pan-JAK inhibitor.

description: Small molecule binding data for protein Tyrosine-protein kinase JAK1, Tyrosine-protein kinase JAK2, and Tyrosine-protein kinase JAK3, Uniprot O60674, P23458, and P52333
DOI: 10.7270/q27w6h8t
title: BindingDB Entry 50017208: Discovery of EP300/CBP histone acetyltransferase inhibitors through scaffold hopping of 1,4-oxazepane ring.

description: Small molecule binding data for protein CREB-binding protein, Histone acetyltransferase KAT2A, Histone acetyltransferase KAT2B, Histone acetyltransferase KAT5, Histone acetyltransferase KAT6B, Histone acetyltransferase KAT7, and Histone acetyltransferase p300, Uniprot O95251, Q09472, Q8WYB5, Q92793, Q92830, Q92831, and Q92993
DOI: 10.7270/q2cn77zp
title: BindingDB Entry 50017207: Investigation on the chemical space of the substituted triazole thio-benzoxazepinone RIPK1 inhibitors.

description: Small molecule binding data for protein Receptor-interacting serine/threonine-protein kinase 1, Uniprot Q13546
DOI: 10.6084/m9.figshare.22722688.v2
title: <strong>Extended data</strong>

description: Extended data of manuscript.
DOI: 10.7270/q2hd80qv
title: BindingDB Entry 50017202: Concise synthesis and preliminary biological evaluation of new triazolylthioacetone derivatives bearing pyridine, pyrazine, and 3,4,5-trimethoxybenzyl fragment.

description: Small molecule binding data for protein Vascular endothelial growth factor receptor 2, Uniprot P35968
DOI: 10.7270/q2n58rf6
title: BindingDB Entry 50017201: Polyphenolic compounds: Synthesis, assessment of antimicrobial effect and enzymes inhibition against important medicinal enzymes with computational details.

description: Small molecule binding data for protein Acetylcholinesterase, Cholinesterase, and Tyrosinase, Uniprot P06276, P14679, and P22303
DOI: 10.7270/q2rx9h45
title: BindingDB Entry 50017200: Synthesis and biological evaluation of 1,2,4-triazole derivatives as potential Nrf2 activators for the treatment of cerebral ischemic injury.

description: Small molecule binding data for protein Potassium voltage-gated channel subfamily H member 2, Uniprot Q12809
DOI: 10.7270/q2wq07v1
title: BindingDB Entry 50017198: Quinazolinones as allosteric fourth-generation EGFR inhibitors for the treatment of NSCLC.

description: Small molecule binding data for protein Epidermal growth factor receptor, Uniprot P00533
DOI: 10.7270/q21g0r9w
title: BindingDB Entry 50017195: Discovery of small-molecule inhibitors of RUVBL1/2 ATPase.

description: Small molecule binding data for protein RuvB-like 1 and RuvB-like 2, Uniprot Q9Y230 and Q9Y265
DOI: 10.7270/q2542snb
title: BindingDB Entry 50017190: Synthesis and biological evaluation of new series of quinazoline derivatives as EGFR/HER2 dual-target inhibitors.

description: Small molecule binding data for protein Epidermal growth factor receptor, Uniprot P00533
DOI: 10.7270/q28w3jb9
title: BindingDB Entry 50017182: Design, synthesis and biological evaluation of novel pyridine derivatives as gut-selective NaPi2b inhibitors.

description: Small molecule binding data for protein Sodium-dependent phosphate transport protein 2B, Uniprot O95436 and Q9JJ09
DOI: 10.7270/q2dn493g
title: BindingDB Entry 50017176: Pyrrolidinyl benzofurans and benzodioxanes: Selective α4β2 nicotinic acetylcholine receptor ligands with different activity profiles at the two receptor stoichiometries.

description: Small molecule binding data for protein Neuronal acetylcholine receptor subunit alpha-3/beta-4 and Neuronal acetylcholine receptor subunit alpha-4/beta-2, Uniprot P04757, P09483, P12390, P12392, P17787, and P43681
DOI: 10.7270/q2jd51v7
title: BindingDB Entry 50017174: Development of disulfide-functionalized peptides covalently binding G protein-coupled receptors.

description: Small molecule binding data for protein Neurotensin receptor type 1 and Neurotensin receptor type 2, Uniprot O95665 and P30989
DOI: 10.7270/q2p55skk
title: BindingDB Entry 50017172: Thiosemicarbazone derivatives: Evaluation as cruzipain inhibitors and molecular modeling study of complexes with cruzain.

description: Small molecule binding data for protein Cruzipain, Uniprot P25779