cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.5886946
title: Power analysis by simulation (binomial models) of various sampling protocol scenarios for the analysis of Natura 2000 habitats conservation states trends.

description: The aim of this work is to generate simulations of various sampling protocols of a longitudinal study of binary data. The conservation status of a site is evaluated as good or bad. This evaluation is repeated on several sites and repeated over time.<br><br>The main interest is to evaluate the proportion of sites in good or bad conservation state during the first year (initial situation) and then to evaluate how the situation<br>change over time (trends).<br><br>We want to evaluate the influence of the sampling size, frequency, repetition, etc... on the statistical power and the size of the confidence intervals.<br><br>A first function generate the simulations, analyze the fake dataset and stores the model parameters.<br>A grid of function parameters is generated to apply this first function with various combinations of options corresponding to various sampling protocols.<br>A second function aggregate these results for each combination of parameters and compute descriptive statistics like the power of the tests and the confidence<br>intervals of the parameters<br>The outputs are saved on the disc and are available for data visualization (produced in another script).<br><br>The pdf report present a graphical exploration of the results of these simulations.<br><br>The "results" directory contains the ouput of the raw simulations : output_simulations_initial.csv are simulation for one year only to estimate the initial proportion of sites in bad conservation state. output_simulations_trends.csv contains simulations of dataset over several years to explore the statistical power of the slopes/trends over time. there are 50 simulations for each combination of parameters.<br><br>The 2 other files are aggregated versions of these files. The 50 simulations for each combination of parameters are grouped to compute the statistical power and confidence intervals. <br><br>This approach of power analysis is described by Gelman & Hill (2007) : Gelman A, Hill J (2007) Data analysis using regression and multilevel/hierarchical models. Cambridge University Press
DOI: 10.6084/m9.figshare.5886946.v2
title: Power analysis by simulation (binomial models) of various sampling protocol scenarios for the analysis of Natura 2000 habitats conservation states trends.

description: The aim of this work is to generate simulations of various sampling protocols of a longitudinal study of binary data. The conservation status of a site is evaluated as good or bad. This evaluation is repeated on several sites and repeated over time.<br><br>The main interest is to evaluate the proportion of sites in good or bad conservation state during the first year (initial situation) and then to evaluate how the situation<br>change over time (trends).<br><br>We want to evaluate the influence of the sampling size, frequency, repetition, etc... on the statistical power and the size of the confidence intervals.<br><br>A first function generate the simulations, analyze the fake dataset and stores the model parameters.<br>A grid of function parameters is generated to apply this first function with various combinations of options corresponding to various sampling protocols.<br>A second function aggregate these results for each combination of parameters and compute descriptive statistics like the power of the tests and the confidence<br>intervals of the parameters<br>The outputs are saved on the disc and are available for data visualization (produced in another script).<br><br>The pdf report present a graphical exploration of the results of these simulations.<br><br>The "results" directory contains the ouput of the raw simulations : output_simulations_initial.csv are simulation for one year only to estimate the initial proportion of sites in bad conservation state. output_simulations_trends.csv contains simulations of dataset over several years to explore the statistical power of the slopes/trends over time. there are 50 simulations for each combination of parameters.<br><br>The 2 other files are aggregated versions of these files. The 50 simulations for each combination of parameters are grouped to compute the statistical power and confidence intervals. <br><br>This approach of power analysis is described by Gelman & Hill (2007) : Gelman A, Hill J (2007) Data analysis using regression and multilevel/hierarchical models. Cambridge University Press
DOI: 10.6084/m9.figshare.5886946.v1
title: Power analysis for longitudinal binary data

description: The aim of this work is to generate simulations of various sampling protocols of a longitudinal study of binary data. The conservation status of a site is evaluated as good or bad. This evaluation is repeated on several sites and repeated over time.<br><br>The main interest is to evaluate the proportion of sites in good or bad conservation state during the first year (initial situation) and then to evaluate how the situation<br>change over time (trends).<br><br>We want to evaluate the influence of the sampling size, frequency, repetition, etc... on the statistical power and the size of the confidence intervals.<br><br>A first function generate the simulations, analyze the fake dataset and stores the model parameters.<br>A grid of function parameters is generated to apply this first function with various combinations of options corresponding to various sampling protocols.<br>A second function aggregate these results for each combination of parameters and compute descriptive statistics like the power of the tests and the confidence<br>intervals of the parameters<br>The outputs are saved on the disc and are available for data visualization (produced in another script).<br><br>The pdf report present a graphical exploration of the results of these simulations.<br><br>The "results" directory contains the ouput of the raw simulations : output_simulations_initial.csv are simulation for one year only to estimate the initial proportion of sites in bad conservation state. output_simulations_trends.csv contains simulations of dataset over several years to explore the statistical power of the slopes/trends over time. there are 50 simulations for each combination of parameters.<br><br>The 2 other files are aggregated versions of these files. The 50 simulations for each combination of parameters are grouped to compute the statistical power and confidence intervals. <br><br>This approach of power analysis is described by Gelman & Hill (2007) : Gelman A, Hill J (2007) Data analysis using regression and multilevel/hierarchical models. Cambridge University Press
DOI: 10.6084/m9.figshare.5886835
title: Intermolecular cyclization of cinnamoyl isothiocyanate: A new synthetic entry for pyrimidine, triazine, and triazole candidates

description: An efficient and facile protocol for the synthesis of azine and azole ring systems was reported. Whereas, reaction of cinnamoyl isothiocyanate with <i>N</i>-nucleophile containing compounds (namely, <i>p</i>-aminophenol (<b>2</b>), <i>N</i><sup>1</sup>-phenylbenzene-1,4-diamine (<b>5</b>) and <i>p</i>-aminoacetophenone (<b>8</b>)) tolerated thiourea derivatives <b>3, 6</b>, and <b>9</b>, respectively. The later compounds underwent intramolecular cyclization upon treatment with EtONa to give pyrimidinethiones <b>4, 7</b>, and <b>10</b>, respectively, in moderate yield (74–79%). Compound <b>9</b> underwent intramolecular cyclization and condensation upon reaction with NaOH and benzaldehyde to give pyrimidinethione <b>12</b>. Thiosemicarbazides <b>14</b> and <b>19</b> were obtained through reaction of heteroallen <b>1</b> with 2,4-dinitrophenylhydrazine <b>13</b> and hydrazone <b>18</b>, respectively. Compound <b>14</b> was cyclized to pyrimidinethione <b>15</b> and triazine derivatives <b>17</b> through its reaction with EtONa at room temperature and refluxing temperature, respectively. Finally, base mediated and oxidative cyclization of thiourea derivative <b>19</b> with EtONa, Br<sub>2</sub>/AcOH, and Pb(OAc)<sub>2</sub> afforded thiadiazole <b>20</b>, benzothiazolotriazole <b>21</b>, and triazolethione <b>22</b> derivatives, respectively.
DOI: 10.6084/m9.figshare.5886835.v1
title: Intermolecular cyclization of cinnamoyl isothiocyanate: A new synthetic entry for pyrimidine, triazine, and triazole candidates

description: An efficient and facile protocol for the synthesis of azine and azole ring systems was reported. Whereas, reaction of cinnamoyl isothiocyanate with <i>N</i>-nucleophile containing compounds (namely, <i>p</i>-aminophenol (<b>2</b>), <i>N</i><sup>1</sup>-phenylbenzene-1,4-diamine (<b>5</b>) and <i>p</i>-aminoacetophenone (<b>8</b>)) tolerated thiourea derivatives <b>3, 6</b>, and <b>9</b>, respectively. The later compounds underwent intramolecular cyclization upon treatment with EtONa to give pyrimidinethiones <b>4, 7</b>, and <b>10</b>, respectively, in moderate yield (74–79%). Compound <b>9</b> underwent intramolecular cyclization and condensation upon reaction with NaOH and benzaldehyde to give pyrimidinethione <b>12</b>. Thiosemicarbazides <b>14</b> and <b>19</b> were obtained through reaction of heteroallen <b>1</b> with 2,4-dinitrophenylhydrazine <b>13</b> and hydrazone <b>18</b>, respectively. Compound <b>14</b> was cyclized to pyrimidinethione <b>15</b> and triazine derivatives <b>17</b> through its reaction with EtONa at room temperature and refluxing temperature, respectively. Finally, base mediated and oxidative cyclization of thiourea derivative <b>19</b> with EtONa, Br<sub>2</sub>/AcOH, and Pb(OAc)<sub>2</sub> afforded thiadiazole <b>20</b>, benzothiazolotriazole <b>21</b>, and triazolethione <b>22</b> derivatives, respectively.
DOI: 10.6084/m9.figshare.5886790
title: Dataset for: Bi-directional Scaling of Vocal Variability by an Avian Cortico-Basal Ganglia Circuit

description: Behavioral variability is thought to be critical for trial and error learning, but where such motor exploration is generated in the central nervous system is unclear. The zebra finch songbird species offers a highly appropriate model in which to address this question. The male song is amenable to detailed measurements of variability, while the brain contains an identified cortico-basal ganglia loop that underlies this behavior. We used pharmacogenetic interventions to separately interrogate cortical and basal ganglia nodes of zebra finch song control circuitry. We show that bi-directional manipulations of each node produce near mirror image changes in vocal control: Cortical activity promotes song variability whereas basal ganglia activity promotes song stability. Furthermore, female conspecifics can evaluate these pharmacogenetically-elicited changes in song quality. Our results indicate that cortex and striatopallidum can jointly and reciprocally affect behaviorally relevant levels of vocal variability, and point to endogenous mechanisms for its control.
DOI: 10.6084/m9.figshare.5886790.v1
title: Dataset for: Bi-directional Scaling of Vocal Variability by an Avian Cortico-Basal Ganglia Circuit

description: Behavioral variability is thought to be critical for trial and error learning, but where such motor exploration is generated in the central nervous system is unclear. The zebra finch songbird species offers a highly appropriate model in which to address this question. The male song is amenable to detailed measurements of variability, while the brain contains an identified cortico-basal ganglia loop that underlies this behavior. We used pharmacogenetic interventions to separately interrogate cortical and basal ganglia nodes of zebra finch song control circuitry. We show that bi-directional manipulations of each node produce near mirror image changes in vocal control: Cortical activity promotes song variability whereas basal ganglia activity promotes song stability. Furthermore, female conspecifics can evaluate these pharmacogenetically-elicited changes in song quality. Our results indicate that cortex and striatopallidum can jointly and reciprocally affect behaviorally relevant levels of vocal variability, and point to endogenous mechanisms for its control.
DOI: 10.6084/m9.figshare.5886778
title: Raw data used in the study: Inhibition of biofilm formation on the surface of water storage containers using biosand zeolite silver-impregnated clay granular and silver impregnated porous pot filtration systems.

description: Raw data used in the study: <b>Inhibition of biofilm formation on the surface of water storage containers using biosand zeolite silver-impregnated clay granular and silver impregnated porous pot filtration systems.</b><b></b>
DOI: 10.6084/m9.figshare.5886778.v1
title: Raw data used in the study: Inhibition of biofilm formation on the surface of water storage containers using biosand zeolite silver-impregnated clay granular and silver impregnated porous pot filtration systems.

description: Raw data used in the study: <b>Inhibition of biofilm formation on the surface of water storage containers using biosand zeolite silver-impregnated clay granular and silver impregnated porous pot filtration systems.</b><b></b>
DOI: 10.6084/m9.figshare.5886613
title: SBU-POSE

description: human body part dataset for depth sensor (SBU-POSE)The database Farpose was collected for our huamn pose estimation project in shahid beheshti university. The dataset contains about 5k training images and test images of 5 people. For each frame, a depth image of 640x480 pixels and the Ground truth label is provided.
DOI: 10.6084/m9.figshare.5886613.v1
title: SBU-POSE

description: human body part dataset for depth sensor (SBU-POSE)The database Farpose was collected for our huamn pose estimation project in shahid beheshti university. The dataset contains about 5k training images and test images of 5 people. For each frame, a depth image of 640x480 pixels and the Ground truth label is provided.
DOI: 10.6084/m9.figshare.5886580
title: Temporal stability of attention capture effects: Dataset

description: The data include two .csv-files corresponding to analyses of attention capture's temporal stability/reliability. The file "data_experiment1.csv" includes the data for the first experiment; the file "data_experiment2.csv" includes the data for the second experiment. <br>
DOI: 10.6084/m9.figshare.5886580.v2
title: Temporal stability of attention capture effects: Dataset

description: The data include two .csv-files corresponding to analyses of attention capture's temporal stability/reliability. The file "data_experiment1.csv" includes the data for the first experiment; the file "data_experiment2.csv" includes the data for the second experiment. <br>
DOI: 10.6084/m9.figshare.5886580.v1
title: Temporal stability of attention capture effects: Dataset

description: The data include two .csv-files corresponding to analyses of attention capture's temporal stability/reliability. The file "data_experiment1.csv" includes the data for the first experiment; the file "data_experiment2.csv" includes the data for the second experiment. <br>
DOI: 10.6084/m9.figshare.5886532
title: CitySounds2017train audio files

description: The CitySounds2017<i><sub>train</sub> </i>dataset comprising 1100 1-minute <i>.wav</i> audio files recorded at 44 green infrastructure sites within Greater London, UK between 2013 and 2015.<br>Audio data captured using a Song Meter SM2+ digital audio field recorder (Wildlife Acoustics, Inc., Concord, Massachusetts, USA). The recorder was equipped with a single omnidirectional microphone (frequency response: -35±4 dB) oriented horizontally at a height of 1 metre.
DOI: 10.6084/m9.figshare.5886472
title: Supplementary Material for: Three Novel Heterozygous COL4A4 Mutations Result in Three Different Collagen Type IV Kidney Disease Phenotypes

description: Thin basement membrane nephropathy (TBMN), autosomal dominant Alport syndrome (ADAS), and focal segmental glomerulosclerosis (FSGS) are kidney diseases that differ in clinical diagnosis, treatment, and prognosis. Nevertheless, they may result from the same causative genes. Here, we report 3 <i>COL4A4 </i>heterozygous mutations (p.Gly208Arg, p.Ser513Glufs*2, and p.Met1617Cysfs*39) that lead to 3 different collagen type IV kidney disease phenotypes, manifesting as TBMN, ADAS, and FSGS. Using bioinformatics analyses and pedigree verification, we show that these novel variants are pathogenetic and cosegregate with TBMN, ADAS, and FSGS. Furthermore, we found that the collagen type IV-associated kidney disease phenotypes are heterogeneous, with overlapping pathology and genetic mutations. We propose that <i>COL4A4</i>-associated TBMN, ADAS, and FSGS should be considered as collagen type IV kidney disease subtypes that represent different phases of disease progression.
DOI: 10.6084/m9.figshare.5886472.v1
title: Supplementary Material for: Three Novel Heterozygous COL4A4 Mutations Result in Three Different Collagen Type IV Kidney Disease Phenotypes

description: Thin basement membrane nephropathy (TBMN), autosomal dominant Alport syndrome (ADAS), and focal segmental glomerulosclerosis (FSGS) are kidney diseases that differ in clinical diagnosis, treatment, and prognosis. Nevertheless, they may result from the same causative genes. Here, we report 3 <i>COL4A4 </i>heterozygous mutations (p.Gly208Arg, p.Ser513Glufs*2, and p.Met1617Cysfs*39) that lead to 3 different collagen type IV kidney disease phenotypes, manifesting as TBMN, ADAS, and FSGS. Using bioinformatics analyses and pedigree verification, we show that these novel variants are pathogenetic and cosegregate with TBMN, ADAS, and FSGS. Furthermore, we found that the collagen type IV-associated kidney disease phenotypes are heterogeneous, with overlapping pathology and genetic mutations. We propose that <i>COL4A4</i>-associated TBMN, ADAS, and FSGS should be considered as collagen type IV kidney disease subtypes that represent different phases of disease progression.
DOI: 10.6084/m9.figshare.5886454
title: Matlab codes to simulate 3-phase model (see Mazzocco et al., Plos One, 2017)

description: Matlab code scripts to estimate model parameters with the 3-phase model presented in Mazzocco et al., Plos One 2017.<br>The main script is in the file 'ParamEstimate'. Other files are auxiliary functions.
DOI: 10.6084/m9.figshare.5886445
title: Supplementary Material for: Psychotic Symptoms and Attitudes toward Medication Mediate the Effect of Insight on Personal-Social Functions in Patients with Schizophrenia: One-Year Randomized Controlled Trial and Follow-Up

description: <b><i>Aims:</i></b> This study aimed to investigate the mediating pathway of 3 factors (psychotic symptoms, attitude toward medication, and cognitive processing speed) on the effect of insight on personal-social functioning in patients with schizophrenia. <b><i>Methods:</i></b> Chinese inpatients with schizophrenia (<i>n</i> = 168; mean age 18 ± 50 years) diagnosed according to the DSM-IV were randomly assigned to treatment with antipsychotic medication alone or combined treatment. Positive and Negative Syndrome Scale (PANSS), Drug Attitude Inventory (DAI), Assessment of Insight (SAI), and Social-Personal Performance Scale (PSPS) scores were evaluated at baseline and at 3, 6, and 12 months. Cognitive function was assessed at baseline. Multiple mediation analyses were conducted with baseline data, end point data, and changes-in-scale scores between baseline and the end point, respectively. <b><i>Results:</i></b> At baseline and at 12 months, only psychotic symptoms mediated the effect of insight on personal-social functioning. For changes-in-scale scores over the 12-month follow-up, in patients receiving treatment with medication alone, the effect of improved insight on improved personal-social function was mediated by psychotic symptoms only; in patients receiving a combined treatment, the effect of improved insight on improved personal-social functioning was mediated by both psychotic symptoms and attitudes toward medication, independently. <b><i>Conclusions:</i></b><i></i> The link between insight and personal-social functions is mainly mediated by psychotic symptoms. Psychosocial intervention improves the predicting effect of insight on personal-social function by improving both the attitude toward medication and psychotic symptoms independently.
DOI: 10.6084/m9.figshare.5886445.v1
title: Supplementary Material for: Psychotic Symptoms and Attitudes toward Medication Mediate the Effect of Insight on Personal-Social Functions in Patients with Schizophrenia: One-Year Randomized Controlled Trial and Follow-Up

description: <b><i>Aims:</i></b> This study aimed to investigate the mediating pathway of 3 factors (psychotic symptoms, attitude toward medication, and cognitive processing speed) on the effect of insight on personal-social functioning in patients with schizophrenia. <b><i>Methods:</i></b> Chinese inpatients with schizophrenia (<i>n</i> = 168; mean age 18 ± 50 years) diagnosed according to the DSM-IV were randomly assigned to treatment with antipsychotic medication alone or combined treatment. Positive and Negative Syndrome Scale (PANSS), Drug Attitude Inventory (DAI), Assessment of Insight (SAI), and Social-Personal Performance Scale (PSPS) scores were evaluated at baseline and at 3, 6, and 12 months. Cognitive function was assessed at baseline. Multiple mediation analyses were conducted with baseline data, end point data, and changes-in-scale scores between baseline and the end point, respectively. <b><i>Results:</i></b> At baseline and at 12 months, only psychotic symptoms mediated the effect of insight on personal-social functioning. For changes-in-scale scores over the 12-month follow-up, in patients receiving treatment with medication alone, the effect of improved insight on improved personal-social function was mediated by psychotic symptoms only; in patients receiving a combined treatment, the effect of improved insight on improved personal-social functioning was mediated by both psychotic symptoms and attitudes toward medication, independently. <b><i>Conclusions:</i></b><i></i> The link between insight and personal-social functions is mainly mediated by psychotic symptoms. Psychosocial intervention improves the predicting effect of insight on personal-social function by improving both the attitude toward medication and psychotic symptoms independently.
DOI: 10.6084/m9.figshare.5886424
title: Dataset for: Bayesian modelling of lung function data from multiple-breath washout tests

description: Paediatric respiratory researchers have widely adopted the multiple-breath washout (MBW) test because it allows assessment of lung function in unsedated infants and is well suited to longitudinal studies of lung development and disease. However, a substantial proportion of MBW tests in infants fail current acceptability criteria. We hypothesised that a model-based approach to analysing the data, in place of traditional simple empirical summaries, would enable more efficient use of these tests. We therefore developed a novel statistical model for infant MBW data and applied it to 1,197 tests from 432 individuals from a large birth cohort study. We focus on Bayesian estimation of the lung clearance index (LCI), the most commonly used summary of lung function from MBW tests. Our results show that the model provides an excellent fit to the data and shed further light on statistical properties of the standard empirical approach. Furthermore, the modelling approach enables LCI to be estimated using tests with different degrees of completeness, something not possible with the standard approach. Our model therefore allows previously unused data to be used rather than discarded, as well as routine use of shorter tests without significant loss of precision. Beyond our specific application, our work illustrates a number of important aspects of Bayesian modelling in practice, such as the importance of hierarchical specifications to account for repeated measurements and the value of model checking via posterior predictive distributions.