cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.25345/c5j205
title: MassIVE MSV000086359 - Dual-acting IspH inhibitors kill Gram-negative bacteria and mobilize immune clearance
title: Isoprenoids are vital to all organisms in supporting core functions of life, like respiration and membrane stability. IspH, an enzyme in the methyl erythritol phosphate pathway of isoprenoid synthesis, is essential to gram-negative bacteria, mycobacteria and apicomplexans. The IspH substrate, HMBPP, is not produced in humans and other metazoans and activates cytotoxic T-cells in humans and primates at extremely low concentrations. We describe novel IspH inhibitors and through structure-guided analog design, refine their potency to nanomolar levels. We have modified these into prodrugs for delivery into bacteria and report that they kill clinical isolates of several multidrug resistant bacterial species such as Acinetobacter, Pseudomonas, Klebsiella, Enterobacter, Vibrio, Shigella, Salmonella, Yersinia, Mycobacterium and Bacillus, while being relatively non-toxic to mammalian cells. Proteomic analysis reveals that bacteria treated with prodrugs resemble those with conditional IspH knockdown. Notably, these prodrugs also cause expansion and activation of human T-cells in a humanized mouse model of bacterial infection. These IspH prodrugs synergize direct antibiotic killing with a simultaneous rapid immune response by cytotoxic T-cells, thus inhibiting the rise of antibiotic resistant bacterial populations.
DOI: 10.21227/5x30-6s87
title: Baseline 10

description: Baseline 10
DOI: 10.6084/m9.figshare.13128866.v1
title: R0310_20191120a_videos

description: Rat 0310, skilled reaching data collected in Leventhal laboratory by Alexandra Bova
DOI: 10.6084/m9.figshare.13132877
title: Habitat selection of samango monkeys at the 2nd order

description: This dataset represents location data on two samango monkey groups at Lajuma Research Centre, in the Soutpansberg Mountains, South Africa (2012 - 2016). The dataset also includes landscape variables sampled for each point. 2nd order selection.
DOI: 10.6084/m9.figshare.13132877.v1
title: Habitat selection of samango monkeys at the 2nd order

description: This dataset represents location data on two samango monkey groups at Lajuma Research Centre, in the Soutpansberg Mountains, South Africa (2012 - 2016). The dataset also includes landscape variables sampled for each point. 2nd order selection.
DOI: 10.6084/m9.figshare.13132889.v1
title: Habitat selection of samango monkeys at the 3rd order

description: This dataset represents location data on two samango monkey groups at Lajuma Research Centre, in the Soutpansberg Mountains, South Africa (2012 - 2016). The dataset also includes landscape variables sampled for each point. 3rd order selection.
DOI: 10.6084/m9.figshare.13132889
title: Habitat selection of samango monkeys at the 3rd order

description: This dataset represents location data on two samango monkey groups at Lajuma Research Centre, in the Soutpansberg Mountains, South Africa (2012 - 2016). The dataset also includes landscape variables sampled for each point. 3rd order selection.
DOI: 10.6084/m9.figshare.13132898
title: Habitat selection of samango monkeys at the 4th order

description: This dataset represents location data on two samango monkey groups at Lajuma Research Centre, in the Soutpansberg Mountains, South Africa (2012 - 2016). The dataset also includes landscape variables sampled for each point. 4th order selection.
DOI: 10.6084/m9.figshare.13132898.v1
title: Habitat selection of samango monkeys at the 4th order

description: This dataset represents location data on two samango monkey groups at Lajuma Research Centre, in the Soutpansberg Mountains, South Africa (2012 - 2016). The dataset also includes landscape variables sampled for each point. 4th order selection.
DOI: 10.21227/6xt2-4b81
title: x

description: x
DOI: 10.5517/ccdc.csd.cc24f2b0
title: CCDC 1978771: Experimental Crystal Structure Determination

description: Related Article: Guobing Zhang, Ruikun Chen, Mingxiang Sun, Minkyu Kim, Weiwei Wang, Longzhen Qiu, Kilwon Cho, Yunsheng Ding|2020|J.Mater.Chem.C|8|14180|doi:10.1039/D0TC03629C
description: Related Article: Guobing Zhang, Kilwon Cho, Yunsheng Ding, Longzhen Qiu, Hong-Bo Lu, Mingxiang Sun, Weiwei Wang, MinKyu Kim|2020|CSD Communication|||
DOI: 10.5517/ccdc.csd.cc25dmqy
title: CCDC 2008140: Experimental Crystal Structure Determination

description: Related Article: Yinghua Li, Weibin Fan, Zilong Zhang, Xingkun Xie, Shiqun Xiang, Deguang Huang|2020|Dalton Trans.|49|12189|doi:10.1039/D0DT02288H
DOI: 10.5517/ccdc.csd.cc25n1zw
title: CCDC 2015278: Experimental Crystal Structure Determination

description: Related Article: San-Tai Wang, Shu-Hua Zhang, Wei-Hui Fang, Jian Zhang|2020|Inorg.Chem.|59|13760|doi:10.1021/acs.inorgchem.0c02119
DOI: 10.5517/ccdc.csd.cc25n20y
title: CCDC 2015279: Experimental Crystal Structure Determination

description: Related Article: San-Tai Wang, Shu-Hua Zhang, Wei-Hui Fang, Jian Zhang|2020|Inorg.Chem.|59|13760|doi:10.1021/acs.inorgchem.0c02119
DOI: 10.5517/ccdc.csd.cc25n220
title: CCDC 2015281: Experimental Crystal Structure Determination

description: Related Article: San-Tai Wang, Shu-Hua Zhang, Wei-Hui Fang, Jian Zhang|2020|Inorg.Chem.|59|13760|doi:10.1021/acs.inorgchem.0c02119
DOI: 10.5517/ccdc.csd.cc25n242
title: CCDC 2015283: Experimental Crystal Structure Determination

description: Related Article: San-Tai Wang, Shu-Hua Zhang, Wei-Hui Fang, Jian Zhang|2020|Inorg.Chem.|59|13760|doi:10.1021/acs.inorgchem.0c02119
DOI: 10.5517/ccdc.csd.cc25n264
title: CCDC 2015285: Experimental Crystal Structure Determination

description: Related Article: San-Tai Wang, Shu-Hua Zhang, Wei-Hui Fang, Jian Zhang|2020|Inorg.Chem.|59|13760|doi:10.1021/acs.inorgchem.0c02119
DOI: 10.5517/ccdc.csd.cc25n275
title: CCDC 2015286: Experimental Crystal Structure Determination

description: Related Article: San-Tai Wang, Shu-Hua Zhang, Wei-Hui Fang, Jian Zhang|2020|Inorg.Chem.|59|13760|doi:10.1021/acs.inorgchem.0c02119
DOI: 10.5517/ccdc.csd.cc25xdq7
title: CCDC 2023299: Experimental Crystal Structure Determination

description: Related Article: Xian-Qun Bai, Yu-Jian, Xiu-Ying Qin|2009|Huagong jishu Yu Kaifa|38|11|
DOI: 10.5517/ccdc.csd.cc25xfh1
title: CCDC 2023323: Experimental Crystal Structure Determination

description: Related Article:  Finlay A. Walton|2020|Thesis|||
DOI: 10.5517/ccdc.csd.cc25xfj2
title: CCDC 2023324: Experimental Crystal Structure Determination

description: Related Article:  Finlay A. Walton|2020|Thesis|||
DOI: 10.5517/ccdc.csd.cc25n21z
title: CCDC 2015280: Experimental Crystal Structure Determination

description: Related Article: San-Tai Wang, Shu-Hua Zhang, Wei-Hui Fang, Jian Zhang|2020|Inorg.Chem.|59|13760|doi:10.1021/acs.inorgchem.0c02119
DOI: 10.5517/ccdc.csd.cc25n253
title: CCDC 2015284: Experimental Crystal Structure Determination

description: Related Article: San-Tai Wang, Shu-Hua Zhang, Wei-Hui Fang, Jian Zhang|2020|Inorg.Chem.|59|13760|doi:10.1021/acs.inorgchem.0c02119
DOI: 10.5517/ccdc.csd.cc25xh4r
title: CCDC 2023374: Experimental Crystal Structure Determination

description: Related Article: Kedar U. Narvekar, Vishal M. Pawar, Vishnu S. Nadkarni, Bikshandarkoil R. Srinivasan|2020|CSD Communication|||
DOI: 10.5517/ccdc.csd.cc25xh5s
title: CCDC 2023375: Experimental Crystal Structure Determination

description: Related Article: Kedar U. Narvekar, Vishal M. Pawar, Vishnu S. Nadkarni, Bikshandarkoil R. Srinivasan|2020|CSD Communication|||
DOI: 10.6084/m9.figshare.8279705
title: Do as I Do, Not as I Say: Do Contribution Guidelines Match the GitHub Contribution Process?

description: This zip file contains the process maps that resulted from the process mining phase as well as the raw event data, a csv file that contains the themes we coded from project contribution guidelines, and the coding index we built for the themes.It also includes a notebook we built to count the frequency of the themes.<br>
DOI: 10.6084/m9.figshare.8279705.v1
title: Do as I Do, Not as I Say: Do Contribution Guidelines Match the GitHub Contribution Process?

description: This zip file contains the process maps that resulted from the process mining phase as well as the raw event data, a csv file that contains the themes we coded from project contribution guidelines, and the coding index we built for the themes.It also includes a notebook we built to count the frequency of the themes.<br>
DOI: 10.6073/pasta/4f5377189d13ebc0b7dd6d53d4c8f50b
title: Annual monitoring of high marsh plots dominated by Juncus and Borrichia at the GCE LTER from 2013 - 2019

description: Annual monitoring of high marsh plots dominated by Juncus and Borrichia. Plots were established at GCE sites 6 and 10 in 2013, and are monitored annually. The goal is to determine how annual variation in climate and other abiotic factors affects the vegetation composition.
DOI: 10.6073/pasta/0faa83ce3168a2bb18d6897c6cf879ab
title: Disturbance to permanent monitoring plots at GCE sites 1-10, from 2001 to 2019.

description: We established permanent vegetation monitoring plots in creekbank and midmarsh at GCE sites 1-10 in 2000. A dedicated Juncus zone was later added at sites 10 and 9. Starting in 2001, when we recorded plant sizes, we also noted any disturbance to the plots. Plots were scored as normal (no visible disturbance), disturbed by wrack (wrack present in plots and stems dead or broken), disturbed by snails (&gt;100 Littoraria per square meter and plant biomass low), disturbed by pigs (animal trail through the plot, this mostly happened at site 8 mid-marsh), initial slump (plot at the creekbank sliding into the creek based on movement of pvc poles or formation of a crevasse), and terminal slump (plot had slid far enough down that vegetation had drowned). Plots that experienced terminal slump or could not be found for any reason were scored as lost. Lost plots were replaced with a new plot in the same general area with the plot code incremented by 10. For example if plot 3 was lost, it was replaced by 13, and then in turn by 23.
DOI: 10.6073/pasta/8426ac068706b5d02e6edb0222601445
title: GCE-LTER Altamaha River Plant Community Monitoring Survey in October 2018

description: A quadrat survey was conducted in October 2018 to measure the species and size distribution of plants at 3 sampling sites on the creekbank of the Altamaha River. The sites were chosen to capture the transition from Spartina alterniflora to Spartina cynosuroides (site SCSA) and the transition from Spartina cynosuroides to Zizaniopsis miliacea (sites ZSC1 and ZSC2). The quadrats were established as permanent plots in October 2012 by placing PVC stakes along the creekbank at each site. Plots were evenly spaced, but were not randomly located because the goal was to start with mixtures of vegetation in most of the plots, and vegetation was distributed in patches along the creekbanks. Therefore, these plots provide useful measures of vegetation change, but are not a random sample of the vegetation at the site. Plots will be replaced each year as necessary to replace any lost to disturbance. The plots were visually surveyed and the species, shoot height, and flowering status was recorded individually for each shoot over 10 cm in height present in each plot. Observations from plots exhibiting signs of disturbance were noted in a separate data set. This survey will be repeated annually to assess changes in plant distribution and biomass in relation to environmental changes documented by other GCE LTER monitoring efforts.
DOI: 10.6073/pasta/4fed55c11edd1d8363104b58781ed3b9
title: Fall 2018 plant monitoring survey -- shoot height and flowering status of plants in permanent plots at GCE sampling sites 1-10

description: A quadrat survey was conducted in October 2018 to measure the species and size distribution of plants at 10 GCE LTER sampling sites. The quadrats were established as permanent plots at GCE sampling sites in October 2000 by placing wooden stakes at random locations across two nominal zones at each site, designated based on marsh structure (creekbank and high marsh). New plots were added each year as necessary to replace those lost due to catastrophic wrack disturbance or creek bank erosion. The plots were visually surveyed and the species, shoot height, and flowering status was recorded individually for each shoot over 10 cm in height present in each plot. Observations from plots exhibiting signs of disturbance were noted in a separate data set (GCE-GCEM-1801). This survey will be repeated annually to assess changes in plant distribution and biomass in relation to environmental changes documented by other GCE LTER monitoring efforts.
DOI: 10.6073/pasta/63d853ede5db61cee533c817ffd6aec5
title: Fall 2018 plant monitoring survey -- biomass calculated from shoot height and flowering status of plants in permanent plots at GCE sampling sites 1-10

description: The biomass of plants surveyed in permanent plots at 10 GCE LTER sampling sites in October 2018 was estimated based on allometric relationships between biomass and shoot height and flowering status derived for each site, zone, and species in October 2002 and October 2008. Biomass was calculated for dominant species, including Spartina alterniflora, S. cynosuroides, Juncus roemerianus, and Zizaniopsis miliacea, as well as rarer species including Scirpus spp, Panicum spp. And Typha angustifolia. This data set is based on GCE plant monitoring survey data set PLT-GCEM-1811a, and allometric relationships were based on GCE data sets PLT-GCEM-0211b and PLT-GCEM-0812a.
DOI: 10.6073/pasta/2618c32427f72a0ec183f805486cd516
title: Fall 2018 crab population monitoring: mid-marsh and creek bank abundance based on crab hole counts at GCE marsh, monitoring sites 1-10

description: This data set is the Fall 2018 estimate of crab densities at the GCE-LTER marsh sites used for population monitoring. Crab abundance was determined by counting the number of crab holes within a 625 cm^2 quadrat and converting the counts to number per square meter. Counts were made in the mid-marsh and creek bank zones (n = 4 per zone) at GCE sites 1 through 10. Note that this census method does not differentiate which species made a particular hole and therefore only estimates total burrowing crab abundance, potentially including species Uca pugnax, Uca minax, Uca pugilator, Armases cinereum, Eurytium limosum and Sesarma reticulatum. Crab holes that are not actively maintained are quickly covered by tidal activity and other sediment disturbances, therefore plugged holes were assumed to be unoccupied and excluded from the counts.
DOI: 10.6073/pasta/ee0a2f9a4bbf4e1c06c9ac74fafcc938
title: Fall 2018 grasshopper monitoring -- mid-marsh grasshopper abundance and species diversity at eight GCE LTER sampling sites

description: Grasshopper abundance and species diversity were investigated at eight sampling sites within the Georgia Coastal Ecosystems (GCE) LTER study area in July 2018. Visual surveys were conducted along 8 2m by 10m transects randomly allocated within the mid-marsh zone at each site. All grasshoppers observed within each transect were counted and identified to species, if possible. This survey was conducted as part of the GCE invertebrate monitoring program, and will be performed annually to assess long-term changes in relative species abundances across the GCE study area.
DOI: 10.6073/pasta/5b2677d031a46eaf618083232ae8b8da
title: Yearly survey of barnacle settlement in mid-marsh and creekbank plots at GCE LTER study sites in October 2018

description: To characterize spatial variation in barnacle recruitment within two zones in the salt marsh, the mid-marsh and creekbank, and across a gradient in salinity and distance to ocean, we deployed PVC poles to passive sample barnacle settlement. Eight poles were deployed between 4-5m apart in each marsh zone at each GCE LTER permanent monitoring site each Fall beginning in 2012. These poles were then collected the following Fall and all barnacle that settled on the poles were identified and counted on 50cm-long sections of the 8, 3/4" diameter PVC poles. Although a few other barnacle species are occur within this estuary, only two species settled on poles: Chlathamus fragilis and Balanus spp. This year Geukensia and Oysters that settled on the poles were counted and recorded.
DOI: 10.6073/pasta/68b1727f28282eef1ba7569287f90c66
title: Survey of adult and juvenile periwinkle snail (Littoraria irrorata) density in mid-marsh and creekbank plots at GCE LTER study sites in October 2018.

description: To characterize spatial variation in the adult and juvenile density of periwinkle snails, Littoraria irrorata, within two zones in the salt marsh, the mid-marsh and creekbank, and across a gradient in salinity and distance to ocean, we surveyed snail density in October 2018. In each marsh zone at each GCE LTER permanent monitoring site, we counted the number of adult and juvenile snails in 8 replicate quadrats.
DOI: 10.6073/pasta/4189f2213a7ae69ee8d8e1c6a2132d16
title: Soil salinity at GCE-LTER vegetation monitoring plots in October 2016

description: Soil samples were collected in conjunction with Fall 2016 plant monitoring at half of the permanent vegetation monitoring plots in the creekbank and midmarsh zones at 10 GCE study sites. Pore-water salinity was determined by analysis of supernatant salinity in dried soil samples hydrated with a measured volume of deionized water.
DOI: 10.6073/pasta/b85b43242e6989d3002a6b36ba1ee88e
title: Soil salinity at GCE-LTER vegetation monitoring plots in October 2017

description: Soil samples were collected in conjunction with Fall 2017 plant monitoring at half of the permanent vegetation monitoring plots in the creekbank and midmarsh zones at 10 GCE study sites. Pore-water salinity was determined by analysis of supernatant salinity in dried soil samples hydrated with a measured volume of deionized water.
DOI: 10.6073/pasta/de7e49be5aa8fa00762ceb090241e708
title: Soil salinity at GCE-LTER vegetation monitoring plots in October 2018

description: Soil samples were collected in conjunction with Fall 2018 plant monitoring at half of the permanent vegetation monitoring plots in the creekbank and midmarsh zones at 10 GCE study sites. Pore-water salinity was determined by analysis of supernatant salinity in dried soil samples hydrated with a measured volume of deionized water.
DOI: 10.6073/pasta/89b5006323cd1a116ff087d7ce4c8276
title: Soil salinity at GCE-LTER vegetation monitoring plots in October 2019

description: Soil samples were collected in conjunction with Fall 2019 plant monitoring at half of the permanent vegetation monitoring plots in the creekbank and midmarsh zones at 10 GCE study sites. Pore-water salinity was determined by analysis of supernatant salinity in dried soil samples hydrated with a measured volume of deionized water.
DOI: 10.6073/pasta/96b56cdf5b8ab3f697e2146c2ad6d9ee
title: Grasshopper counts and feeding damage at the GCE-LTER Seawater Addition Long-Term Experiment (SALTEx) in 2016

description: Grasshopper abundance and feeding damage were investigated at the Georgia Coastal Ecosystems (GCE) LTER Seawater Addition Long-Term Experiment (SALTEx) study area approximately monthly in 2016. We conducted visual surveys in each replicate plot and counted 3 species of grasshopper (Romalea, Leptysma, Orchelimum) and scored grasshopper feeding damage on 2 species of plants (Zizaniopsis, Pontederia).
DOI: 10.6084/m9.figshare.12818792
title: Phylogenetic placement of Lesneiidae (Psocodea: Psocomorpha)

description: Molecular dataset (.nex: 18S rRNA, Histone 3, 16S rRNA and COI) used for testing the phylogenetic placement of the family Lesneiidae (Psocodea: Psocomorpha), with trees estimated from this dataset (.tre)
DOI: 10.6084/m9.figshare.12818792.v1
title: Phylogenetic placement of Lesneiidae (Psocodea: Psocomorpha)

description: Molecular dataset (.nex: 18S rRNA, Histone 3, 16S rRNA and COI) used for testing the phylogenetic placement of the family Lesneiidae (Psocodea: Psocomorpha), with trees estimated from this dataset (.tre)
DOI: 10.5281/zenodo.4118631
title: Co-ocurrence patterns of marine catfishes in the Amazonian estuary: Data and coding

description: Data and script to analyze the local co-occurrence patterns of ariids in the Amazonian estuary. These results are discussed in the manuscript "Environmental conditions promote local segregation of catfishes in the Amazonian estuary, but ecomorphological differences may allow aggregation", soon to be submitted as a preprint to EcoEvoRxiv Preprints.
DOI: 10.5281/zenodo.4118630
title: Co-ocurrence patterns of marine catfishes in the Amazonian estuary: Data and coding

description: Data and script to analyze the local co-occurrence patterns of ariids in the Amazonian estuary. These results are discussed in the manuscript "Environmental conditions promote local segregation of catfishes in the Amazonian estuary, but ecomorphological differences may allow aggregation", soon to be submitted as a preprint to EcoEvoRxiv Preprints.
DOI: 10.5517/ccdc.csd.cc25y1z5
title: CCDC 2023927: Experimental Crystal Structure Determination

description: Related Article: M. D. Gheorghiu, L. Parvulescu, K. M. Turdibekov, Yu. T. Struchkov|1990|Rev.Roum.Chim.|35|127|doi:10.1002/chin.199144128
DOI: 10.5517/ccdc.csd.cc2592wg
title: CCDC 2004735: Experimental Crystal Structure Determination

description: Related Article: Ning-Fang Li, Ye-Min Han, Jia-Nian Li, Jia-Peng Cao, Ze-Yu Du, Yan Xu|2020|RSC Advances|10|33628|doi:10.1039/D0RA05926A
DOI: 10.5517/ccdc.csd.cc25q6fk
title: CCDC 2017338: Experimental Crystal Structure Determination

description: Related Article: Akhtaruzzaman, Samim Khan, Asma A. Alothman, Basudeb Dutta, Saikh Mohammad Wabaidur, Seikh Mafiz Alam, Md. Maidul Islam, Mohammad Hedayetullah Mir|2020|Polyhedron|190|114777|doi:10.1016/j.poly.2020.114777
DOI: 10.5517/ccdc.csd.cc25d8rm
title: CCDC 2007800: Experimental Crystal Structure Determination

description: Related Article: Junling Chen, Bo Li, Zhenzhen Shi, Cheng He, Chunying Duan, Tiexin Zhang, Li-Ya Wang|2020|CrystEngComm|22|6612|doi:10.1039/D0CE01004A
DOI: 10.6084/m9.figshare.12442733.v4
title: Source Data for Swelling Manuscript

description: This is all the raw data files generated in novel experiments for the swelling manuscript. Mostly excel files.
DOI: 10.34683/sr2201
title: StoneRounds Case: SR2201
title: Protanopia

description: StoneRounds Case SR2201 was diagnosed with Protanopia likely caused by mutations in the gene: L/M OPSIN Cluster.
DOI: 10.25919/5f91ea7425745
title: Parkes observations for project P971 semester 2020APRS_06

description: We propose timing observations of the relativistic pulsar - white-dwarf binary PSR J1141-6545. This unique system offers access to a wide range of physics, from relativistic phenomena through pulsar emission cone studies, to the structure and distribution of interstellar plasma along our line-of-sight. The recently installed Parkes Ultra Wide Band Low Frequency (UWL) receiver has opened up the possibility of performing first-ever studies of its orbital dynamics at high temporal resolution and study of the effects of the intra-binary medium on the dispersion and polarisation of the pulse profile. Our analysis of data obtained to date suggests that the pulsar would precess away from our line-of-sight in the next 3-5 years. Hence, regular observations are crucial to maximizing its science outcome
DOI: 10.5281/zenodo.4118709
title: Predicting ultrafast nonlinear dynamics in fibre optics with a recurrent neural network

description: Full simulation data sets for "Predicting ultrafast nonlinear dynamics in fibre optics with a recurrent neural network". See https://gitlab.com/salmelal/rnnnonlinear and https://arxiv.org/abs/2004.14126 for details.
DOI: 10.21227/qar3-6872
title: Baseline

description: Simple Baseline