cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.14009442
title: Quantitative results of the analysis of human bioengineered tissues corresponding to the work "Development of novel squid gladius biomaterials for cornea tissue engineering"

description: This dataset corresponds to the quantitative data generated in the work entitled "Development of novel squid gladius biomaterials for cornea tissue engineering".

Cornea tissue engineering is strictly dependent on the development of biomaterials fulfilling the strict biocompatibility, biomechanical and optical requirements of this organ. In this work, we have generated novel biomaterials from the squid gladius (SG) and their application in cornea tissue engineering was evaluated. Results revealed that the native SG (N-SG) was biocompatible in laboratory animals, although a local inflammatory reaction was driven by the material. Cellularized biomaterials (C-SG) demonstrated that the SG provides an adequate substrate for cell attachment and growth, and corneal epithelial cells cultured on this biomaterial were able to express crystallin alpha, a marker for this type of cells. Biomechanical analyses showed that N-SG biomaterials have higher Young modulus and lower traction deformation than control native corneas (CTR), and C-SG showed similar Young modulus than CTR. Analysis of the optical properties of these samples revealed that the diffuse transmittance of N-SG and C-SG were higher than CTR, with the diffuse reflectance showing the opposite behavior. These results confirm the putative usefulness of this abundant marine-derived biomaterial that can be obtained as a byproduct of the fishing industry.
description: Dataset containing the quantitative results of the biomechanical, optical and biochemical analyses of the following tissues and biomaterials:



NATIVE SQUID GLADIUS (N-SG)

CELLULARIZED SQUID GLADIUS (C-SG)

NATIVE CORNEA (CTR)
DOI: 10.5281/zenodo.14009443
title: Quantitative results of the analysis of human bioengineered tissues corresponding to the work "Development of novel squid gladius biomaterials for cornea tissue engineering"

description: This dataset corresponds to the quantitative data generated in the work entitled "Development of novel squid gladius biomaterials for cornea tissue engineering".

Cornea tissue engineering is strictly dependent on the development of biomaterials fulfilling the strict biocompatibility, biomechanical and optical requirements of this organ. In this work, we have generated novel biomaterials from the squid gladius (SG) and their application in cornea tissue engineering was evaluated. Results revealed that the native SG (N-SG) was biocompatible in laboratory animals, although a local inflammatory reaction was driven by the material. Cellularized biomaterials (C-SG) demonstrated that the SG provides an adequate substrate for cell attachment and growth, and corneal epithelial cells cultured on this biomaterial were able to express crystallin alpha, a marker for this type of cells. Biomechanical analyses showed that N-SG biomaterials have higher Young modulus and lower traction deformation than control native corneas (CTR), and C-SG showed similar Young modulus than CTR. Analysis of the optical properties of these samples revealed that the diffuse transmittance of N-SG and C-SG were higher than CTR, with the diffuse reflectance showing the opposite behavior. These results confirm the putative usefulness of this abundant marine-derived biomaterial that can be obtained as a byproduct of the fishing industry.
description: Dataset containing the quantitative results of the biomechanical, optical and biochemical analyses of the following tissues and biomaterials:



NATIVE SQUID GLADIUS (N-SG)

CELLULARIZED SQUID GLADIUS (C-SG)

NATIVE CORNEA (CTR)
DOI: 10.5281/zenodo.14210696
title: Quantitative results of the analysis of human bioengineered tissues corresponding to the work "Development of novel squid gladius biomaterials for cornea tissue engineering"

description: This dataset corresponds to the quantitative data generated in the work entitled "Development of novel squid gladius biomaterials for cornea tissue engineering".

Cornea tissue engineering is strictly dependent on the development of biomaterials fulfilling the strict biocompatibility, biomechanical and optical requirements of this organ. In this work, we have generated novel biomaterials from the squid gladius (SG) and their application in cornea tissue engineering was evaluated. Results revealed that the native SG (N-SG) was biocompatible in laboratory animals, although a local inflammatory reaction was driven by the material. Cellularized biomaterials (C-SG) demonstrated that the SG provides an adequate substrate for cell attachment and growth, and corneal epithelial cells cultured on this biomaterial were able to express crystallin alpha, a marker for this type of cells. Biomechanical analyses showed that N-SG biomaterials have higher Young modulus and lower traction deformation than control native corneas (CTR), and C-SG showed similar Young modulus than CTR. Analysis of the optical properties of these samples revealed that the diffuse transmittance of N-SG and C-SG were higher than CTR, with the diffuse reflectance showing the opposite behavior. These results confirm the putative usefulness of this abundant marine-derived biomaterial that can be obtained as a byproduct of the fishing industry.
description: Dataset containing the quantitative results of the biomechanical, optical and biochemical analyses of the following tissues and biomaterials:



NATIVE SQUID GLADIUS (N-SG)

CELLULARIZED SQUID GLADIUS (C-SG)

NATIVE CORNEA (CTR)
DOI: 10.15468/dl.3fbh6z
title: Occurrence Download

description: A dataset containing 171 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Hyporthodus flavolimbatus (Poey, 1865)",
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 "Year is greater than or equal to 1900"
 ]
}

 The dataset includes 171 records from 30 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0053332-241126133413365/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.10845878
title: Quantitative results of the analysis of human native and bioengineered tissues corresponding to the work "Histological, histochemical and immunohistochemical characterization of NANOULCOR nanostructured fibrin-agarose human cornea substitutes generated by tissue engineering"

description: Dataset containing the quantitative results of the histochemical and immunohistochemical analysis of the following human tissues:



Control native cornea (CTR-C)

Control native limbus (CTR-L)

Artificial cornea generated by tissue engineering (HAC)


Each tissue type was subjected to histochemical and immunohistochemical analyses and results were quantified using ImageJ software to determine average intensities and area fractions corresponding to positive staining signal for each marker.
description: This dataset contains the raw data corresponding to the manuscript "Histological, histochemical and immunohistochemical characterization of NANOULCOR nanostructured fibrin-agarose human cornea substitutes generated by tissue engineering". Human artificial corneas (HAC) generated by tissue engineering recently demonstrated clinical usefulness in the management of complex corneal diseases. However, the biological mechanisms associated to their regenerative potential needs to be elucidated. In the present work, we generated HAC using nanostructured fibrin-agarose biomaterials with cultured corneal epithelial and stromal cells, and we compared the structure and histochemical and immunohistochemical profiles of HAC with control native corneas (CTR-C) and limbus (CTR-L) to determine the level of biomimicry of the HAC with these two native organs. Results showed that HAC tissues consisted of a stratified epithelium and a cellular stromal substitute. The interface between stroma and epithelium was similar to that of CTR-C, without the finger-shaped palisades of Vogt found in CTR-L, and contained a poorly-developed basement membrane as determined by PAS histochemistry. Analysis of the stromal layer revealed that HAC contained significantly lower amounts of extracellular matrix components (collagen, proteoglycans, decorin, keratocan and lumican) than CTR-C and CTR-L, with all samples being devoid of elastic and reticular fibers. At the epithelial level, HAC were strongly positive for several cytokeratins, although KRT5 was lower in HAC as compared to CTR-C and CTR-L. The expression of crystallin lambda was lower in HAC than in control tissues, whereas crystallin alpha-a was similar in HAC and CTR-C. No differences were found among HAC and controls for the cell-cell junction proteins CX43 and TJP1. When specific markers were analyzed, we found that HAC expression profile of KRT3, KRT19, KRT15 and ΔNp63 was more similar to CTR-L than to CTR-C. These results suggest that HAC generated in the laboratory could be structurally and functionally more biomimetic to the structure found at the corneal limbus than to the central cornea, and open the door to the use of these artificial tissues in patients with limbal deficiency.
DOI: 10.5281/zenodo.10845879
title: Quantitative results of the analysis of human native and bioengineered tissues corresponding to the work "Histological, histochemical and immunohistochemical characterization of NANOULCOR nanostructured fibrin-agarose human cornea substitutes generated by tissue engineering"

description: Dataset containing the quantitative results of the histochemical and immunohistochemical analysis of the following human tissues:



Control native cornea (CTR-C)

Control native limbus (CTR-L)

Artificial cornea generated by tissue engineering (HAC)


Each tissue type was subjected to histochemical and immunohistochemical analyses and results were quantified using ImageJ software to determine average intensities and area fractions corresponding to positive staining signal for each marker.
description: This dataset contains the raw data corresponding to the manuscript "Histological, histochemical and immunohistochemical characterization of NANOULCOR nanostructured fibrin-agarose human cornea substitutes generated by tissue engineering". Human artificial corneas (HAC) generated by tissue engineering recently demonstrated clinical usefulness in the management of complex corneal diseases. However, the biological mechanisms associated to their regenerative potential needs to be elucidated. In the present work, we generated HAC using nanostructured fibrin-agarose biomaterials with cultured corneal epithelial and stromal cells, and we compared the structure and histochemical and immunohistochemical profiles of HAC with control native corneas (CTR-C) and limbus (CTR-L) to determine the level of biomimicry of the HAC with these two native organs. Results showed that HAC tissues consisted of a stratified epithelium and a cellular stromal substitute. The interface between stroma and epithelium was similar to that of CTR-C, without the finger-shaped palisades of Vogt found in CTR-L, and contained a poorly-developed basement membrane as determined by PAS histochemistry. Analysis of the stromal layer revealed that HAC contained significantly lower amounts of extracellular matrix components (collagen, proteoglycans, decorin, keratocan and lumican) than CTR-C and CTR-L, with all samples being devoid of elastic and reticular fibers. At the epithelial level, HAC were strongly positive for several cytokeratins, although KRT5 was lower in HAC as compared to CTR-C and CTR-L. The expression of crystallin lambda was lower in HAC than in control tissues, whereas crystallin alpha-a was similar in HAC and CTR-C. No differences were found among HAC and controls for the cell-cell junction proteins CX43 and TJP1. When specific markers were analyzed, we found that HAC expression profile of KRT3, KRT19, KRT15 and ΔNp63 was more similar to CTR-L than to CTR-C. These results suggest that HAC generated in the laboratory could be structurally and functionally more biomimetic to the structure found at the corneal limbus than to the central cornea, and open the door to the use of these artificial tissues in patients with limbal deficiency.
DOI: 10.15468/dl.jtxhxs
title: Occurrence Download

description: A dataset containing 539 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Hyporthodus niveatus (Valenciennes, 1828)",
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 "Year is greater than or equal to 1900"
 ]
}

 The dataset includes 539 records from 43 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0053333-241126133413365/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.mmwehb
title: Occurrence Download

description: A dataset containing 569 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Icelinus borealis Gilbert, 1896",
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 "Year is greater than or equal to 1900"
 ]
}

 The dataset includes 569 records from 29 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0053334-241126133413365/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.auba2x
title: Occurrence Download

description: A dataset containing 72 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Icelinus burchami Evermann & Goldsborough, 1907",
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 "Year is greater than or equal to 1900"
 ]
}

 The dataset includes 72 records from 19 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0053335-241126133413365/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.xvuv8v
title: Occurrence Download

description: A dataset containing 1993 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Icelinus filamentosus Gilbert, 1890",
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 "Year is greater than or equal to 1900"
 ]
}

 The dataset includes 1993 records from 30 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0053336-241126133413365/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.bv28nw
title: Occurrence Download

description: A dataset containing 27 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Icelinus fimbriatus Gilbert, 1890",
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 "Year is greater than or equal to 1900"
 ]
}

 The dataset includes 27 records from 10 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0053337-241126133413365/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.m5u9v4
title: Occurrence Download

description: A dataset containing 398 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Icelinus tenuis Gilbert, 1890",
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 "Year is greater than or equal to 1900"
 ]
}

 The dataset includes 398 records from 26 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0053338-241126133413365/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.u8nymk
title: Occurrence Download

description: A dataset containing 1448 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Icelus bicornis (Reinhardt, 1840)",
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 "Year is greater than or equal to 1900"
 ]
}

 The dataset includes 1448 records from 37 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0053339-241126133413365/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.xezpga
title: Occurrence Download

description: A dataset containing 2174 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Icelus spatula Gilbert & Burke, 1912",
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 "Year is greater than or equal to 1900"
 ]
}

 The dataset includes 2174 records from 33 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0053340-241126133413365/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.z8uuur
title: Occurrence Download

description: A dataset containing 304 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Icelus spiniger Gilbert, 1896",
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 "Year is greater than or equal to 1900"
 ]
}

 The dataset includes 304 records from 25 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0053341-241126133413365/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.34740/kaggle/dsv/10349901
title: Vietnam SARS-CoV-2 | COVID-19 Data
DOI: 10.15468/dl.t5zg86
title: Occurrence Download

description: A dataset containing 949 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Icichthys lockingtoni Jordan & Gilbert, 1880",
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 "Year is greater than or equal to 1900"
 ]
}

 The dataset includes 949 records from 24 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0053343-241126133413365/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.xh93rd
title: Occurrence Download

description: A dataset containing 616 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Icosteus aenigmaticus Lockington, 1880",
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 "Year is greater than or equal to 1900"
 ]
}

 The dataset includes 616 records from 24 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0053344-241126133413365/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5517/ccdc.csd.cc2hkwnm
title: CCDC 2311101: Experimental Crystal Structure Determination

description: Related Article: Mengjie Cen, Xinyue Ma, Xi Yang, Shangshang Zhang, Long Liu, Michal Szostak, Tieqiao Chen|2024|Chemical Science|15|20346|doi:10.1039/D4SC05429F
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2hz0n5
title: CCDC 2322757: Experimental Crystal Structure Determination

description: Related Article: Kai Hua, Fei Xie, Shengfa Ye, Ming-Tian Zhang|2024|JACS Au|4|4406|doi:10.1021/jacsau.4c00745
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2hz0p6
title: CCDC 2322758: Experimental Crystal Structure Determination

description: Related Article: Kai Hua, Fei Xie, Shengfa Ye, Ming-Tian Zhang|2024|JACS Au|4|4406|doi:10.1021/jacsau.4c00745
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.15468/dl.ufzhyt
title: Occurrence Download

description: A dataset containing 849 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Idiacanthus antrostomus Gilbert, 1890",
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 "Year is greater than or equal to 1900"
 ]
}

 The dataset includes 849 records from 35 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0053346-241126133413365/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5517/ccdc.csd.cc2l58y0
title: CCDC 2388362: Experimental Crystal Structure Determination

description: Related Article: Jeppe Granhøj, Viktor Bliksted Roug Pedersen, Kurt V. Mikkelsen, Mogens Brøndsted Nielsen|2024|Org.Biomol.Chem.|22|9259|doi:10.1039/D4OB01755B
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2l58z1
title: CCDC 2388363: Experimental Crystal Structure Determination

description: Related Article: Jeppe Granhøj, Viktor Bliksted Roug Pedersen, Kurt V. Mikkelsen, Mogens Brøndsted Nielsen|2024|Org.Biomol.Chem.|22|9259|doi:10.1039/D4OB01755B
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.15468/dl.r9ymwe
title: Occurrence Download

description: A dataset containing 88 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is one of (Human Observation, Material citation, Specimen, Occurrence evidence)",
 "Country is Mexico",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "TaxonKey is Lontra longicaudis annectens (Major, 1897)"
 ]
}

 The dataset includes 88 records from 17 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0053347-241126133413365/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.