cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.27270496
title: A systematic review of the efficacy and safety of anti-amyloid beta monoclonal antibodies in treatment of Alzheimer’s disease

description: Alzheimer’s disease can cause dementia through brain matter degradation. This study investigates the monoclonal antibody usage for AD treatment, following PRISMA 2020 guidelines, and aims to discern the monoclonal antibody that offers the optimal balance of efficacy and safety for individuals with AD. A systematic search was conducted across databases such as PubMed, Cochrane Library, and clinical trial registries for randomized controlled trials. The quality of studies was assessed using the Cochrane risk of bias 2 tool. Cognitive function and daily activities were evaluated using MMSE, ADAS-Cog, and CDR-SB test data. According to CDR-SB measurements, lecanemab showed effectiveness in reducing brain amyloid and cognitive decline, with a change from baseline of 1.21. Aducanumab resulted in a decrease of −0.39 (−22%). Bapineuzumab showed no significant benefit, with scores of 2.4 (2.8). Gantenerumab, scoring 1.69 (1.37, 2.01), reduces amyloid, particularly in early Alzheimer’s stages. Crenezumab was ineffective, with a score of 3.61. The findings provide various perspectives. Lecanemab showed the most promise in brain amyloid reduction and decelerating cognitive decline compared to the other therapies. Further research is needed, highlighting the necessity of AD therapeutic research to alter AD’s trajectory and provide reliable treatment. www.crd.york.ac.uk/prospero identifier is CRD42024504358 This study investigates the safety and efficacy of treating Alzheimer’s disease (AD) with monoclonal antibodies. In order to determine which antibody could be most helpful, we looked over a number of trials. Several antibodies, such as lecanemab, solanezumab, aducanumab, bapineuzumab, gantenerumab, and crenezumab, were the subject of the study. According to our research, lecanemab is particularly effective at lowering brain amyloid plaques and delaying cognitive deterioration, two major problems associated with Alzheimer’s disease. Other antibodies, such as solanezumab and bapineuzumab, had little to no beneficial effects, making their benefits less evident. The contradictory results of aducanumab indicate that further research is necessary to ascertain its actual efficacy. When administered at the earliest stages of Alzheimer’s disease or when used at a higher dose, crenezumab may be beneficial. Even though lecanemab seems promising, research in this field is still in its infancy. To validate these results and get further insight into the potential applications of these medicines in the management of Alzheimer’s disease, additional research is required. In summary, this study emphasizes the necessity of ongoing research to discover trustworthy treatments for AD patients.
DOI: 10.6084/m9.figshare.27270496.v2
title: A systematic review of the efficacy and safety of anti-amyloid beta monoclonal antibodies in treatment of Alzheimer’s disease

description: Alzheimer’s disease can cause dementia through brain matter degradation. This study investigates the monoclonal antibody usage for AD treatment, following PRISMA 2020 guidelines, and aims to discern the monoclonal antibody that offers the optimal balance of efficacy and safety for individuals with AD. A systematic search was conducted across databases such as PubMed, Cochrane Library, and clinical trial registries for randomized controlled trials. The quality of studies was assessed using the Cochrane risk of bias 2 tool. Cognitive function and daily activities were evaluated using MMSE, ADAS-Cog, and CDR-SB test data. According to CDR-SB measurements, lecanemab showed effectiveness in reducing brain amyloid and cognitive decline, with a change from baseline of 1.21. Aducanumab resulted in a decrease of −0.39 (−22%). Bapineuzumab showed no significant benefit, with scores of 2.4 (2.8). Gantenerumab, scoring 1.69 (1.37, 2.01), reduces amyloid, particularly in early Alzheimer’s stages. Crenezumab was ineffective, with a score of 3.61. The findings provide various perspectives. Lecanemab showed the most promise in brain amyloid reduction and decelerating cognitive decline compared to the other therapies. Further research is needed, highlighting the necessity of AD therapeutic research to alter AD’s trajectory and provide reliable treatment. www.crd.york.ac.uk/prospero identifier is CRD42024504358 This study investigates the safety and efficacy of treating Alzheimer’s disease (AD) with monoclonal antibodies. In order to determine which antibody could be most helpful, we looked over a number of trials. Several antibodies, such as lecanemab, solanezumab, aducanumab, bapineuzumab, gantenerumab, and crenezumab, were the subject of the study. According to our research, lecanemab is particularly effective at lowering brain amyloid plaques and delaying cognitive deterioration, two major problems associated with Alzheimer’s disease. Other antibodies, such as solanezumab and bapineuzumab, had little to no beneficial effects, making their benefits less evident. The contradictory results of aducanumab indicate that further research is necessary to ascertain its actual efficacy. When administered at the earliest stages of Alzheimer’s disease or when used at a higher dose, crenezumab may be beneficial. Even though lecanemab seems promising, research in this field is still in its infancy. To validate these results and get further insight into the potential applications of these medicines in the management of Alzheimer’s disease, additional research is required. In summary, this study emphasizes the necessity of ongoing research to discover trustworthy treatments for AD patients.
DOI: 10.15151/esrf-es-1838724332
title: Thermal equation of state and spin crossover of (Fe2+, Fe3+)-bearing Al-Phase D

description: Hydrous silicate phase D is considered to be a potentially important carrier and reservoir in Earth’s deep interior. The experiments aim to investigate the crystal structural evolution, thermal equation of state, spin state of iron, and hydrogen bond configuration in (Fe2+, Fe3+)-bearing Al-Phase D utilizing the Single-Crystal X-ray diffraction and Synchrotron Mössbauer Source spectroscopy at high pressure-temperature conditions (up to 80 GPa and 1200 K), and to determine their potential influences on the properties of the Earth’s deep interior.
DOI: 10.15468/dl.h9ny8w
title: Occurrence Download

description: A dataset containing 18814 species occurrences available in GBIF matching the query:
{
 "and" : [
 {
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen)"
 ]
 }
 }
 ]
 },
 "TaxonKey is one of (Sisymbrium orientale L.)"
 ]
}

 The dataset includes 18814 records from 403 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0005989-241126133413365/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.rwdb2v
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Pelor japonicum Cuvier, 1829",
 "Geometry POLYGON((170 20, 170 50, 120 50, 120 20, 170 20))",
 "HasCoordinate is true"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0005990-241126133413365/datasets/export for details.
DOI: 10.15468/dl.7rjz3m
title: Occurrence Download

description: A dataset containing 2 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen)"
 ]
 }
 },
 "TaxonKey is one of (Zhengyia shennongensis T.Deng, D.G.Zhang & H.Sun)"
 ]
}

 The dataset includes 2 records from 2 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0005992-241126133413365/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.8jm9xb
title: Occurrence Download

description: A dataset containing 28775 species occurrences available in GBIF matching the query:
{
 "and" : [
 {
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen)"
 ]
 }
 }
 ]
 },
 "TaxonKey is one of (Amorpha fruticosa L.)"
 ]
}

 The dataset includes 28775 records from 511 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0005991-241126133413365/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.eku8y2
title: Occurrence Download

description: A dataset containing 460 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Carangoides equula (Temminck & Schlegel, 1844)",
 "Geometry POLYGON((170 20, 170 50, 120 50, 120 20, 170 20))",
 "HasCoordinate is true"
 ]
}

 The dataset includes 460 records from 24 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0005993-241126133413365/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.yhyhff
title: Occurrence Download

description: A dataset containing 2103 species occurrences available in GBIF matching the query:
{
 "and" : [
 {
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen)"
 ]
 }
 }
 ]
 },
 "TaxonKey is one of (Astragalus sinicus L.)"
 ]
}

 The dataset includes 2103 records from 84 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0005994-241126133413365/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.14236528
title: Model code and output for "Transformation Processes in the Oder Lagoon as seen from a Model Perspective"

description: This dataset contains the numerical model output files that were used in the analysis, the numerical model input files that were used to produce the model simulation, and the specific source code for the model components presented in "Transformation Processes in the Oder Lagoon as seen from a Model Perspective", submitted to Biogeoscience.

data1.tar is the direct diagnostic model output. data2.tar are condensed data which are used for the analysis.

forcing.tar contains data to run the model. Most files should be placed inside a directory named INPUT/ that resides in the working directory where the model is being run. The following files should be at the top level in the working directory: data_table, diag_table, field_table, input.nml.

For large files, a subset in time (1995) is provided for the first year of the simulation. This dataset does not include the coastdat atmospheric data, which can be downloaded directly from https://www.wdc-climate.de/ui/entry?acronym=coastDat-2_COSMO-CLM.

src.tar contains the model source code.
DOI: 10.5281/zenodo.14236529
title: Model code and output for "Transformation Processes in the Oder Lagoon as seen from a Model Perspective"

description: This dataset contains the numerical model output files that were used in the analysis, the numerical model input files that were used to produce the model simulation, and the specific source code for the model components presented in "Transformation Processes in the Oder Lagoon as seen from a Model Perspective", submitted to Biogeoscience.

data1.tar is the direct diagnostic model output. data2.tar are condensed data which are used for the analysis.

forcing.tar contains data to run the model. Most files should be placed inside a directory named INPUT/ that resides in the working directory where the model is being run. The following files should be at the top level in the working directory: data_table, diag_table, field_table, input.nml.

For large files, a subset in time (1995) is provided for the first year of the simulation. This dataset does not include the coastdat atmospheric data, which can be downloaded directly from https://www.wdc-climate.de/ui/entry?acronym=coastDat-2_COSMO-CLM.

src.tar contains the model source code.
DOI: 10.15468/dl.nq64d5
title: Occurrence Download

description: A dataset containing 66 species occurrences available in GBIF matching the query:
{
 "and" : [
 {
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen)"
 ]
 }
 }
 ]
 },
 "TaxonKey is one of (Lespedeza lichiyuniae T.Nemoto, H.Ohashi & T.Itoh)"
 ]
}

 The dataset includes 66 records from 12 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0005995-241126133413365/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.6amy7v
title: Occurrence Download

description: A dataset containing 2 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen)"
 ]
 }
 },
 "TaxonKey is one of (Zhengyia shennongensis T.Deng, D.G.Zhang & H.Sun)"
 ]
}

 The dataset includes 2 records from 2 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0005997-241126133413365/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.h3kux3
title: Occurrence Download

description: A dataset containing 235 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Kaiwarinus equula (Temminck & Schlegel, 1844)",
 "Geometry POLYGON((170 20, 170 50, 120 50, 120 20, 170 20))",
 "HasCoordinate is true"
 ]
}

 The dataset includes 235 records from 10 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0005996-241126133413365/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.bxvtza
title: Occurrence Download

description: A dataset containing 656 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Potamochoerus larvatus (F.Cuvier, 1822))",
 "BasisOfRecord is one of (Specimen, Human Observation, Observation, Machine Observation)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 656 records from 16 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0005998-241126133413365/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.gemn3v
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen)"
 ]
 }
 },
 "TaxonKey is one of (Metapilea jingxiensis W.T.Wang)"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0006002-241126133413365/datasets/export for details.
DOI: 10.15468/dl.ys754n
title: Occurrence Download

description: A dataset containing 12 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Caranx equula Temminck & Schlegel, 1844",
 "Geometry POLYGON((170 20, 170 50, 120 50, 120 20, 170 20))",
 "HasCoordinate is true"
 ]
}

 The dataset includes 12 records from 3 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0006000-241126133413365/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.km93sw
title: Occurrence Download

description: A dataset containing 2703 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is China",
 "RecordedBy is one of (F. A. McClure, McClure, F. A.)"
 ]
}

 The dataset includes 2703 records from 24 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0006003-241126133413365/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.p86a42
title: Occurrence Download

description: A dataset containing 54006 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Rangifer tarandus (Linnaeus, 1758))",
 "BasisOfRecord is one of (Specimen, Human Observation, Observation, Machine Observation)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 54006 records from 101 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0006001-241126133413365/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.38redr
title: Occurrence Download

description: A dataset containing 41 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen)"
 ]
 }
 },
 "TaxonKey is one of (Acanthochlamys bracteata P.C.Kao)"
 ]
}

 The dataset includes 41 records from 8 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0006004-241126133413365/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.kakcrn
title: Occurrence Download

description: A dataset containing 288 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Zenopsis nebulosa (Temminck & Schlegel, 1845)",
 "Geometry POLYGON((170 20, 170 50, 120 50, 120 20, 170 20))",
 "HasCoordinate is true"
 ]
}

 The dataset includes 288 records from 23 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0006005-241126133413365/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.14238546
title: Enhanced Alzheimer's Brain Scan Dataset: Normal and Synthesized

description: Enhanced Alzheimer's Brain Scan Dataset: Normal and Synthesized












Unveiling the Invisible: A Novel Approach to Alzheimer's Image Analysis

Dataset Overview

This unique dataset comprises two distinct sets of brain scan images related to Alzheimer's disease:



Normal Dataset: 2000 carefully selected images for each stage of Alzheimer's progression.

Synthesized Dataset: Corresponding enhanced images using our innovative pseudo-RGB transformation technique.


Total Images: 16,000 (8,000 normal + 8,000 synthesized)

Why This Dataset Matters



Enhanced Feature Visibility: The synthesized images amplify subtle brain structures that may be indicative of Alzheimer's progression.

Multi-Perspective Analysis: By providing both normal and synthesized versions, this dataset enables researchers to compare and leverage both representations.

Balanced Categories: With equal representation across Alzheimer's stages, this dataset supports unbiased model training.

Novel Research Opportunities: The unique pseudo-RGB transformation opens doors for innovative approaches in medical image analysis.


Potential Applications



Training more accurate deep learning models for Alzheimer's detection

Comparative studies between traditional and enhanced image analysis techniques

Exploration of feature importance in Alzheimer's diagnosis

Development of new visualization tools for medical professionals
DOI: 10.15468/dl.qe6294
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Zeus nebulosus Temminck & Schlegel, 1845",
 "Geometry POLYGON((170 20, 170 50, 120 50, 120 20, 170 20))",
 "HasCoordinate is true"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0006006-241126133413365/datasets/export for details.
DOI: 10.5281/zenodo.13240330
title: IOC World Bird List (IOC) - active: IOC World Bird List

description: This is a Darwin Core Archive version of data from the [IOC World Bird List](http://www.worldbirdnames.org/ "http://www.worldbirdnames.org"). The IOC World Bird List is an open access resource of the international community of ornithologists. Their goal is to facilitate worldwide communication in ornithology and conservation based on an up-to-date classification of world birds and a set of English names that follows explicit guidelines for spelling and construction (Gill & Wright 2006). Citation: Gill, F & D Donsker (Eds). 2017. IOC World Bird List (v 7.1). doi: [10.14344/IOC.ML.7.1] (http://doi.org/10.14344/IOC.ML.7.1) [More...](http://www.worldbirdnames.org/ "http://www.worldbirdnames.org")
description: Simple version without higher classification.











####--- __EOL DwCA resource last updated: Jul 21, 2024 05:29 AM__ ---####
The Encyclopedia of Life (EOL, eol.org) aggregates biodiversity information from more than 400 sources and provides access to the data through taxon pages, visual query and application programming interfaces. Scientific names are essential elements of the data integration infrastructure, but their shortcomings as key identifiers are well documented (Patterson et al., 2016). Complex automated workflows and continuous manual curation are required to address idiosyncrasies of source taxonomies, variation in data quality, and conflicting taxonomic opinions. 

To achieve a harmonized taxonomic view of EOL content, names from data sources are mapped to a dynamic reference hierarchy ([see current version here](https://opendata.eol.org/dataset/tram-807-808-809-810-dh-v1-1/resource/00adb47b-57ed-4f6b-8f66-83bfdb5120e8)) using an algorithm that leverages canonical name strings, hierarchical information (ancestry, descendants), taxonomic ranks, synonym data, and author strings. Names that cannot be associated with a reference taxon are still accessible, but their unmapped status excludes them and any associated content from certain core EOL functions.

For more information about the EOL taxonomy, see [EOL Dynamic Hierarchy](https://eol.org/docs/eol-dynamic-hierarchy)
DOI: 10.15468/dl.jkgjq5
title: Occurrence Download

description: A dataset containing 1 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen)"
 ]
 }
 },
 "TaxonKey is one of (Tetradoxa omeiensis (H.Hara) C.Y.Wu)"
 ]
}

 The dataset includes 1 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0006007-241126133413365/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.dncbgb
title: Occurrence Download

description: A dataset containing 927 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Sebastiscus marmoratus (Cuvier, 1829)",
 "Geometry POLYGON((170 20, 170 50, 120 50, 120 20, 170 20))",
 "HasCoordinate is true"
 ]
}

 The dataset includes 927 records from 35 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0006008-241126133413365/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.