cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.15468/dl.7vs2dc
title: Occurrence Download

description: A dataset containing 1263 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Picea asperata"
 ]
}

 The dataset includes 1263 records from 71 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0006154-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.dez4sj
title: Occurrence Download

description: A dataset containing 9943279 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Panama",
 "OccurrenceStatus is Present",
 "Year 1000-2025"
 ]
}

 The dataset includes 9943279 records from 1711 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0006116-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.26165/juelich-data/a3jb9o
title: FZJ alkaline electrolysis test cell

description: The dataset provides the technical drawings and the assembly instructions for the “FZJ alkaline electrolysis test cell”, developed at Forschungszentrum Jülich, Institute of energy technologies, electrochemical process engineering (IET-4) and used in several benchmark studies including round robin campaigns. It serves to test components for hydrogen production by alkaline and anion exchange membrane electrolysis. The cell has an active area of 5 cm², a serpentine flow field made of nickel, with the necessary connections for fluids, current and voltage, as well as connections for temperature measurement and heating.
DOI: 10.14278/rodare.4102
title: Probing structural and optical modulations in metal-ion co-doped gadolinium vanadate: a combined spectroscopic and diffraction study

description: Data of: <strong>Probing structural and optical modulations in metal-ion co-doped gadolinium vanadate: a combined spectroscopic and diffraction study</strong>
DOI: 10.14278/rodare.4103
title: Probing structural and optical modulations in metal-ion co-doped gadolinium vanadate: a combined spectroscopic and diffraction study

description: Data of: <strong>Probing structural and optical modulations in metal-ion co-doped gadolinium vanadate: a combined spectroscopic and diffraction study</strong>
DOI: 10.57710/alba-es-2024028146
title: Role of the chemotherapy resistance related tubulin isotype beta-III in the microtubule structure and its modulation by chemotherapeutic drugs.

description: Microtubules (MTs) are nanomachines composed of tubulin and microtubule associated
proteins (MAPs). There exist different layers of complexity to regulate this apparently simple
structure. The first level of regulation is based on the chemical state of the tubulin dimer, which is
determined by the nucleotide bound. On top of the nucleotide regulation lays the “tubulin code”,
formed by the expression of different alpha- and beta tubulin isotypes. These two major levels of
regulation are able to call and affect the interaction of MAPs, which regulate MT dynamics and
function mechanisms. Finally, we of small compounds, that bind either to tubulin or MT chemically
regulate MT formation and dynamics.
Given its essential role, MTs have become a successful target for chemotherapy. While first magic
bullets targeting cancer were discovered in the 60´s, lowering the death toll of child leukemias from
95 to 5%, paclitaxel and docetaxel (wide spectrum drugs targeting solid tumours), become first line
therapeutic options for breast, lung and ovarian cancer in the 90´s. Unfortunately, one of the major
drawbacks of paclitaxel and docetaxel treatments is the development of resistance resulting from the
overexpression of the beta3 isotype. Since MT function is regulated through structural changes
which arise from the tubulin structural plasticity on response to the chemical condition of the
nucleotide site and the isotype composition, specially beta3, it is reasonable to suggest that beta3
overexpression affects the structural response of MTs to paclitaxel and docetaxel limiting their
effectivity.
Based on the results obtained from previous proposals, and especially those we expect to have on
our next beam time 2023027372, we expect to understand how isotype composition affect the
structural signals on the microtubule surface and their modulation by chemotherapeutic drugs.
Being the ultimate goal to understand the role of beta3 tubulin isotype in the resistance against
taxanes.
DOI: 10.57903/uj/pgmrba
title: Chiral phases and dynamics of dipoles in triangular optical ladders - replication data

description: This dataset contains the numerical data underlying Figures 2–4 and Supplementary Figures S1–S4 of the associated manuscript on chiral phases in extended Bose–Hubbard and dipolar XXZ models. The ZIP file includes NumPy .npy arrays for phase diagrams, chirality order parameters, momentum distributions, spin correlations, pairing correlators, and real-time local chirality dynamics, covering both ladder EBHM simulations and 1D dipolar spin chains in different geometries. A Python script, read_fig.py, is provided to load these arrays and reproduce all figures from the manuscript, while Figure 1 is purely schematic and has no associated data.
DOI: 10.57710/alba-es-2024078525
title: Evaluation of the architecture and structural integrity of cell walls from edible seaweeds

description: The food industry is increasingly focused on discovering new, effective ways to provide healthy and sustainable protein sources to meet the growing demands of the world’s population. Traditional protein sources, such as meat, dairy products, and soybeans, present challenges including environmental impact, common allergic reactions, and dietary restrictions. Therefore, identifying alternative protein sources that are environmentally friendly and nutritious is crucial. Seaweeds, or macroalgae, are a promising alternative due to their minimal land requirements, negligible water footprint, and lack of need for chemical fertilizers. Nutritionally, seaweeds can contain up to 47% protein with an essential amino acid profile comparable to traditional sources. They are also rich in dietary fiber, vitamins, minerals, and other bioactives, making them suitable for various food applications.
To fully exploit their potential as protein-rich ingredients, it is essential to develop efficient methods to break down or permeabilize their cell walls, which are rich in structural polysaccharides. The goal of this proposal is to characterize the nanostructure of the cell walls from two different seaweed species, Ulva and Nori, by evaluating the changes that occur during the isolation process from their native seaweed biomass under different treatments. We expect to get information on the microfibril crystallinity, dimensions, density and how the polysaccharides present in each seaweed species contribute to the cell wall structure. Additionally, we would like to compare the hydrated and dry samples which will enable determining the arrangement of solvent accessibility. Finally, this characterization is crucial for designing effective methods to disrupt the cell walls and promote the release of proteins and other valuable compounds, thereby enhancing the use of seaweeds as sustainable and nutritious protein.
DOI: 10.6084/m9.figshare.30607946
title: Feammox

description: Our findings provide the first empirical evidence that plant diversity enhances the response of Feammox to drought, underscoring the role of biodiversity in sustaining emerging N loss pathways under climate change.
DOI: 10.6084/m9.figshare.30607946.v1
title: Feammox

description: Our findings provide the first empirical evidence that plant diversity enhances the response of Feammox to drought, underscoring the role of biodiversity in sustaining emerging N loss pathways under climate change.
DOI: 10.6084/m9.figshare.30607946.v2
title: Feammox

description: Our findings provide the first empirical evidence that plant diversity enhances the response of Feammox to drought, underscoring the role of biodiversity in sustaining emerging N loss pathways under climate change.
DOI: 10.15468/dl.yvr3fp
title: Occurrence Download

description: A dataset containing 55313 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Human Observation",
 "Continent is Europe",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "TaxonKey is Procambarus clarkii",
 "Year 1971-2024"
 ]
}

 The dataset includes 55313 records from 449 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0030417-251025141854904/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.57710/alba-es-2024088526
title: In situ SAXS/WAXS investigation of Glyco-Zeolitic-Imidazolate Frameworks (GlycoZIFs): Monitoring the formation of nanosized GlycoZIFs crystals and study of the glyco-ZIF interactions

description: Glycomimetics have attracted much interest as therapeutic agents for a wide variety of diseases; however, their optimal delivery to the target site inside cells is still a major concern. The recently reported strategy to encapsulate a particular type of glycolipid mimetics (sp2-iminoglycolipids) within a zeolitic-imidazolate framework-8 (ZIF-8) nanostructure[1] is a useful approach to enhance the cellular uptake of these glycomimetics and, consequently, improve their therapeutic efficacy at low doses. This advance has opened the path for the preparation of GlycoZIFs with distinctive therapeutic potential depending on the specific glycomimetic encapsulated. However, in situ study of the formation mechanism of these GlycoZIFs and the favorable interactions between glycolipids and ZIF-8 structure have not yet been investigated, limiting the knowledge on the key structural features of these glycolipids necessary for their successful encapsulation, and thus hindering the extension of the synthetic strategy to a more diverse range of glycolipids. We aim to use in situ small-angle X-ray scattering (SAXS) and wide-angle X-ray (WAXS) to obtain real-time monitoring of the nucleation and crystallization equilibriums of GlycoZIFs in comparison to the pristine ZIF-8 nanoparticles, and to study the effect of changes in the structural formula of glycolipids (both the glycone fraction and the aglycone chain) on the mechanism and/or kinetics of the GlycoZIF formation.
DOI: 10.15468/dl.6dx6g9
title: Occurrence Download

description: A dataset containing 110558 species occurrences available in GBIF matching the query:
{
 "DatasetKey" : [
 "is Colección Herbario Federico Medem Bogotá - FMB"
 ]
}

 The dataset includes 110558 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0030431-251025141854904/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.57710/alba-es-2024088539
title: Relationship between the role of crystallization and additive manufacturing processing of biodegradable binary and ternary polyester blends.

description: Additive manufacturing (AM) stands at the forefront of modern fabrication techniques, enabling the creation of intricate three-dimensional objects from CAD models or 3D scans with remarkable material-resource efficiency. This cutting-edge process is ideally suited for producing high-end products across various industries. The most popular AM techniques for thermoplastic materials, namely Extrusion-based technologies and Powder bed fusion, are known for their affordability and simple mechanical design, making them the go-to methods for utilizing amorphous and semicrystalline polymers.
Semicrystalline polymers, in particular, offer outstanding potential for producing AM-printed parts with enhanced strength and durability, surpassing those made from amorphous materials in terms of mechanical and thermal stability. However, controlling the degree of crystallinity (Xc) is essential for preventing warping and maintaining structural integrity and dimensional accuracy during the cooling process. This study aims to develop a groundbreaking method for controlling the Xc and the viscoelastic properties of semicrystalline blends (binary, ternary, and compatibilized blends) by blending various materials with different Xc values.
Understanding the role of each blend component before and after printing, as well as the printing conditions, is paramount in establishing solid relationships between crystallization behavior and the printability of semicrystalline blends. In-situ WAXS/SAXS characterization using different crystallization conditions will provide groundbreaking insights into the evolution of crystallinity based on time, temperature, compositions, nature of blend components, and molecular weight before processing (printing vs. injection). By analyzing processed parts, we will also determine the influence of processing conditions on the crystallization behavior of the blends. SR is crucial for accurately detecting and understanding the structural changes during thermal transitions within a narrow temperature and time range.
DOI: 10.57710/alba-es-2024098628
title: Role of morphology evolution and thermodynamic properties on ionic conductivity of a novel ABA-type triblock copolymers using SAXS/WAXS techniques.

description: Novel ABA-type block copolymers based on styrene and (Vinylbenzyl)trimethylammonium LiTFSI were obtained. These copolymers are attractive materials, in combination with ionic liquids and lithium salts, to be used as solid electrolytes for lithium-ion batteries due to their outstanding properties including high electrochemical and thermal stability and high ionic conductivity. These features, especially the ionic conductivity, are strongly related with the morphology that block copolymers display and their thermodynamic properties. Therefore, we will use SAXS/WAXS experiments at ALBA beamline (BL11 - NCD-SWEET) to study the morphology evolution of these copolymers varying the volume fraction of (Vinylbenzyl)trimethylammonium LiTFSI block, salt concentration and temperature. Our aim is to understand how these parameters affect the performance of these materials when they are used as solid electrolyte to develop high performance lithium-ion batteries prototypes.
DOI: 10.57710/alba-es-2024098683
title: Exploring the Structural Organization and Actuation of Nanogels-Based Enzymatic
Nanomotors at Biological Barriers

description: Enzyme-based nanomotors (NMs), have attracted considerable attention for their high potential in biomedicine. They are able to self-propel through highly viscous biological barriers and modulate their interactions within. This proposal aims to study the structural organization of various environmentally responsive nanogel-based nanomotors (NgNMs) and their ability to modulate biological barriers, focusing on the type of crosslinkers and enzymes used.
DOI: 10.5281/zenodo.17597432
title: Aquaporin-4 Regulates Edema, Sustains Astrocyte Differentiation, and Constrains Immunosuppressive Remodeling in Glioblastoma

description: Vasogenic cerebral edema is a severe complication that affects most patients with glioblastoma (GBM). It leads to an increase in intracranial pressure, neurological deficits, and increased mortality rates. While there is considerable research on edema formation, the molecular and cellular mechanisms of edema resolution in GBM, particularly in response to dexamethasone or other anti-edema therapies, remain largely undefined. Our findings demonstrate that the water channel aquaporin-4 (AQP4), a key regulator of brain water homeostasis, is upregulated in human GBM compared to the normal brain. AQP4 expression correlates with peritumoral edema in GBM patients, with the classical (CL) GBM subtype exhibiting the highest AQP4 levels but the lowest edema content relative to the proneural (PN) and mesenchymal (MES) subtypes. Using the RCAS/tv-a system, we generated de novo GBM with defined driver mutations in Aqp4-proficient and -deficient mice. Loss of Aqp4 shortened survival and exacerbated edema, accompanied by reduced astrocytic coverage within the tumor core, but not at the tumor margin. Single-cell RNA-sequencing and spatial transcriptomics revealed that Aqp4 loss reprograms astrocytes toward an immature, progenitor-like state and alters their crosstalk with other cell types in the GBM microenvironment. Additionally, loss of Aqp4 skewed myeloid populations toward immunosuppressive phenotypes while reducing lymphoid infiltration. Treatment with anti-VEGFA antibody, an established anti-edema therapy, increased expression of Aqp4 and reduced vessel leakage, underscoring the role of AQP4 in the therapeutic modulation of brain water balance. Overall, this study highlights the important role of AQP4 in resolving edema and its critical function in maintaining astrocyte identity and shaping the immune landscape of GBM.

 

This repository contain the spatial transcriptomic data (Visium FFPE) and 10X single cell data of the AQP4 WT/KO backbone in PDGFB tumors
DOI: 10.5281/zenodo.17597431
title: Aquaporin-4 Regulates Edema, Sustains Astrocyte Differentiation, and Constrains Immunosuppressive Remodeling in Glioblastoma

description: Vasogenic cerebral edema is a severe complication that affects most patients with glioblastoma (GBM). It leads to an increase in intracranial pressure, neurological deficits, and increased mortality rates. While there is considerable research on edema formation, the molecular and cellular mechanisms of edema resolution in GBM, particularly in response to dexamethasone or other anti-edema therapies, remain largely undefined. Our findings demonstrate that the water channel aquaporin-4 (AQP4), a key regulator of brain water homeostasis, is upregulated in human GBM compared to the normal brain. AQP4 expression correlates with peritumoral edema in GBM patients, with the classical (CL) GBM subtype exhibiting the highest AQP4 levels but the lowest edema content relative to the proneural (PN) and mesenchymal (MES) subtypes. Using the RCAS/tv-a system, we generated de novo GBM with defined driver mutations in Aqp4-proficient and -deficient mice. Loss of Aqp4 shortened survival and exacerbated edema, accompanied by reduced astrocytic coverage within the tumor core, but not at the tumor margin. Single-cell RNA-sequencing and spatial transcriptomics revealed that Aqp4 loss reprograms astrocytes toward an immature, progenitor-like state and alters their crosstalk with other cell types in the GBM microenvironment. Additionally, loss of Aqp4 skewed myeloid populations toward immunosuppressive phenotypes while reducing lymphoid infiltration. Treatment with anti-VEGFA antibody, an established anti-edema therapy, increased expression of Aqp4 and reduced vessel leakage, underscoring the role of AQP4 in the therapeutic modulation of brain water balance. Overall, this study highlights the important role of AQP4 in resolving edema and its critical function in maintaining astrocyte identity and shaping the immune landscape of GBM.

 

This repository contain the spatial transcriptomic data (Visium FFPE) and 10X single cell data of the AQP4 WT/KO backbone in PDGFB tumors
DOI: 10.57710/alba-es-2024098803
title: A Synergistic Strategy for Treating Metastatic Tumors and Neurodegenerative Disorders via Multifunctional Polypeptide-based Conjugates

description: The design of new polypeptide-based drug delivery carriers represents an opportunity for
diseases with unmet clinical needs, such as neurodegenerative disorders, by improving
pharmacokinetic and pharmacodynamic properties and providing better quality of life for the
patient. Taurine (2-aminoethanesulfonic acid) - the most abundant free amino acid in the human
body - plays a leading role in the nervous system and regulates mechanisms such as
neuroinflammation and antitumorigenic effects.
We designed polypeptide-based carriers using a three-arm star-shaped polyglutamate (st-PGA) and
functionalized it with a taurine moiety. We obtained and characterized a family of taurine
derivatives, performing subsequent crosslinking reactions through biodegradable and nonbiodegradable
strategies to generate final nanosystems with various sizes, conformation, and final
structures. After their physicochemical characterization, ex vivo studies verified their effectiveness.
The nanoparticles comprise two star-shaped polyglutamate-drug conjugates modified by different
crosslinking precursors and crosslinked using flow chemistry at different ratios. Preliminary results
from asymmetric flow field flow fractionation (AF4) coupled with multi-angle light scattering
(MALS) and UV detectors revealed that nanoparticle size decreases using different reactors on
microfluidics. Here, we propose using small-angle X-ray scattering (SAXS) to study these materials
to determine their size and conformation in solution and unravel their aggregation process. Of
particular interest, we aim to combine results from dynamic light scattering (DLS) and AF4
experiments with SAXS profiles to study the viscoelastic properties of polymer with relatively small
amounts of sample.
DOI: 10.34740/kaggle/dsv/13716580
title: Daily Public Opinion on Israel-Palestine War
DOI: 10.34810/data2598
title: Replication data for: Cricket powder (Acheta domesticus) nutritional and techno-functional properties and effects of solid-state fermentation with Pleurotus ostreatus and Rhizopus oligosporus

description: This database contains nutritional and techno-functional properties of cricket powder and the obtained products after sterilization and solid-state fermentation with Pleurotus ostreatus and Rhizopus oligosporus. The ingredients were subjected to sterilization (autoclave) at 121 °C for 15 min, followed by solid-state fermentation with Pleurotus ostreatus or Rhizopus oligosporus after inoculation of suspended mycelium and incubation at 28 °C for 10 days (P. ostreatus) or 4 days (R. oligosporus) in sterile containers. Total nitrogen, non-protein nitrogen, fat, amino acids, indispensable amino acids score, fatty acids, pH, foaming capacity (FC), emulsion stability (ES), water absorption capacity (WAC), oil absorption capacity (OAC), least gelling concentration (LGC) and protein solubility (PS) were determined in the raw, autoclaved and fermented ingredients, to assess the effect of sterilization and fermentation on nutritional and techno-functional properties of cricket powder. The results obtained were discussed in a scientific publication (https://doi.org/10.1016/j.ifset.2025.104066).
DOI: 10.5281/zenodo.17598080
title: NMR spectra

description: This folder contains NMR datasets of new compounds described in the publication entitled: Synthesis and biological evaluation of Retro-2 based PROTACs reveal PEG-linker length and warhead impact on GSPT1 degradation
DOI: 10.5281/zenodo.17598081
title: NMR spectra

description: This folder contains NMR datasets of new compounds described in the publication entitled: Synthesis and biological evaluation of Retro-2 based PROTACs reveal PEG-linker length and warhead impact on GSPT1 degradation
DOI: 10.15468/dl.2k54bj
title: Occurrence Download

description: A dataset containing 4158 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON((152.88872 40.37445,119.07753 54.86492,83.27753 35.82844,104.30301 0.8808,134.98872 25.88402,152.88872 40.37445))",
 "TaxonKey is Alangium platanifolium"
 ]
}

 The dataset includes 4158 records from 130 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0030443-251025141854904/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.