cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.24467053.v1
title: Supplementary Material for: Exceptional response to pembrolizumab in a mismatch-repair deficient aggressive prostate cancer with somatic EPCAM, MSH2 and MSH6 co-deletion: a case report

description: Mismatch repair deficient (dMMR) prostate cancer (PCa) is a rare (1-5%) but highly actionable molecular subgroup of PCa, vulnerable to immune checkpoint inhibitors. Our case of sporadic dMMR PCa due to large monoallelic co-deletion of EPCAM, MSH2 and MSH6, features a clinically aggressive disease presentation and a major response to pembrolizumab. We report a 65-year-old patient with primary metastatic PCa, Gleason score 5+5=10, with penile and lymph node metastases at diagnosis. Patient showed rapid progression on first-line ADT and enzalutamide. Tumor next-generation sequencing (NGS) revealed microsatellite instability and a tumor mutational burden of 40.8 mutations/megabase. Immunohistochemistry showed co-loss of MSH2 and MSH6. Review of NGS row data confirmed large monoallelic deletion in chromosome 2p, including EPCAM, MSH2 and MSH6. No germline alterations in mismatch repair genes were detected. Patient showed excellent response to pembrolizumab, which is still ongoing. We conclude that early molecular tumor profiling is essential to enable personalized management of advanced prostate cancer, especially in patients with aggressive or atypical disease course.
DOI: 10.6084/m9.figshare.24225994
title: Supplementary Material for: Survival Outcome Analysis of Stereotactic Body Radiotherapy and Immunotherapy (SBRT-IO) versus SBRT-alone in Unresectable Hepatocellular Carcinoma (HCC)

description: Introduction While combination of stereotactic body radiotherapy (SBRT) and immunotherapy are promising, their efficacy and safety have not been compared with SBRT-alone in patients with unresectable HCC. Methods This retrospective study included 100 patients with non-metastatic, unresectable HCC in two hospitals. Eligible patients had tumor nodules ≤ 3 and Child-Pugh liver function score of A5 to B7. Seventy patients received SBRT-alone, and 30 patients underwent combined SBRT and immunotherapy (SBRT-IO). Overall survival (OS), time to progression (TTP), overall response rate (ORR), and toxicity were analyzed. We adjusted for the potential confounding factors using propensity score matching. Results The median tumor size was 7.3 cm (range, 2.6 – 18 cm). Twenty-five (25%) of patients had vascular invasion. Before propensity score matching, the 1-year and 3-year OS rate was 89.9% and 59.8% in the SBRT-IO group and 75.7% and 42.3% in SBRT-alone group (p=0.039). After propensity score matching (1:2), 25 and 50 patients were selected from the SBRT-IO and SBRT-alone group. The 1-year and 3-year OS was 92.0% and 63.9% in the SBRT-IO group versus 74.0% and 43.3% in the SBRT-alone group (p=0.034). The 1-year and 3-year TTP was better in SBRT-IO group (1-year: 68.9% versus 58.9% and 3-year: 61.3% versus 32.5%, p=0.057). The ORR of 88% (CR: 56%, PR: 22%) in SBRT-IO arm was significantly better than 50% (CR: 20%, PR: 30%) in the SBRT-alone arm (p=0.006). Three patients (12%) developed ≥ grade 3 immune-related treatment adverse events (n=2 hepatitis, n=1 dermatitis) leading to permanent treatment discontinuation. Discussion / Conclusion Adding immunotherapy to SBRT resulted in better survival with manageable toxicities. Prospective randomized trial is warranted.
DOI: 10.5517/ccdc.csd.cc25scr3
title: CCDC 2019425: Experimental Crystal Structure Determination

description: Related Article: Evgeniya S. Bazhina, Maxim A. Shmelev, Julia K. Voronina, Natalia A. Korotkova, Konstantin A. Babeshkin, Anna K. Matiukhina, Ekaterina V. Belova, Natalia V. Gogoleva, Sergey Yu. Kottsov, Nikolay N. Efimov, Mikhail A. Kiskin, Igor L. Eremenko|2023|New J.Chem.|47|19251|doi:10.1039/D3NJ03027J
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2bkf1d
title: CCDC 2161693: Experimental Crystal Structure Determination

description: Related Article: Evgeniya S. Bazhina, Maxim A. Shmelev, Julia K. Voronina, Natalia A. Korotkova, Konstantin A. Babeshkin, Anna K. Matiukhina, Ekaterina V. Belova, Natalia V. Gogoleva, Sergey Yu. Kottsov, Nikolay N. Efimov, Mikhail A. Kiskin, Igor L. Eremenko|2023|New J.Chem.|47|19251|doi:10.1039/D3NJ03027J
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2bkf2f
title: CCDC 2161694: Experimental Crystal Structure Determination

description: Related Article: Evgeniya S. Bazhina, Maxim A. Shmelev, Julia K. Voronina, Natalia A. Korotkova, Konstantin A. Babeshkin, Anna K. Matiukhina, Ekaterina V. Belova, Natalia V. Gogoleva, Sergey Yu. Kottsov, Nikolay N. Efimov, Mikhail A. Kiskin, Igor L. Eremenko|2023|New J.Chem.|47|19251|doi:10.1039/D3NJ03027J
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2bkf3g
title: CCDC 2161695: Experimental Crystal Structure Determination

description: Related Article: Evgeniya S. Bazhina, Maxim A. Shmelev, Julia K. Voronina, Natalia A. Korotkova, Konstantin A. Babeshkin, Anna K. Matiukhina, Ekaterina V. Belova, Natalia V. Gogoleva, Sergey Yu. Kottsov, Nikolay N. Efimov, Mikhail A. Kiskin, Igor L. Eremenko|2023|New J.Chem.|47|19251|doi:10.1039/D3NJ03027J
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.25403/upresearchdata.24458887
title: Ultrasonic pulse velocity data for Maitland and Stellawood cemeteries, and laboratory experimental data to establish ultrasonic pulse velocity equipment limitations

description: Cemeteries were used as time-series laboratories to assess weathering effects on gabbro stone as a function of different climatic forcings. Tombstones were measured using ultrasonic pulse velocity, which is a recognised assessment proxy for material structural integrity. In order to use this technique, it had to be carefully studied so as to limit experimental error, and then deployed in the field at cemeteries in different locations. The files presented here show the following:Lab work: experiments were carried out to assess the effects of ultrasonic couplant and transducer alignmentField work: An array of tombstones at Maitland Cemetery (Cape Town) and Stellawood Cemetery (Durban) were assessed using the developed experimental method.
DOI: 10.25403/upresearchdata.24458887.v1
title: Ultrasonic pulse velocity data for Maitland and Stellawood cemeteries, and laboratory experimental data to establish ultrasonic pulse velocity equipment limitations

description: Cemeteries were used as time-series laboratories to assess weathering effects on gabbro stone as a function of different climatic forcings. Tombstones were measured using ultrasonic pulse velocity, which is a recognised assessment proxy for material structural integrity. In order to use this technique, it had to be carefully studied so as to limit experimental error, and then deployed in the field at cemeteries in different locations. The files presented here show the following:Lab work: experiments were carried out to assess the effects of ultrasonic couplant and transducer alignmentField work: An array of tombstones at Maitland Cemetery (Cape Town) and Stellawood Cemetery (Durban) were assessed using the developed experimental method.
DOI: 10.5281/zenodo.10065959
title: Another-Trial-of-Depositor-0003

description: This deposition is best described in the following terms...
extending the sentence here, just so that it is obvious that
one can add paragraph(s) of text.
description: Some notes here.
DOI: 10.5281/zenodo.10066004
title: Another-Trial-of-Depositor-0003

description: This deposition is best described in the following terms...
extending the sentence here, just so that it is obvious that
one can add paragraph(s) of text.
description: Some notes here.
DOI: 10.5281/zenodo.10066038
title: Another-Trial-of-Depositor-0003

description: This deposition is best described in the following terms...
extending the sentence here, just so that it is obvious that
one can add paragraph(s) of text.
description: Some notes here.
DOI: 10.5281/zenodo.10066046
title: Another-Trial-of-Depositor-0003

description: This deposition is best described in the following terms...
extending the sentence here, just so that it is obvious that
one can add paragraph(s) of text.
description: Some notes here.
DOI: 10.5281/zenodo.10065958
title: Another-Trial-of-Depositor-0003

description: This deposition is best described in the following terms...
extending the sentence here, just so that it is obvious that
one can add paragraph(s) of text.
description: Some notes here.
DOI: 10.5281/zenodo.10066005
title: Another-Trial-of-Depositor-0003

description: This deposition is best described in the following terms...
extending the sentence here, just so that it is obvious that
one can add paragraph(s) of text.
description: Some notes here.
DOI: 10.22008/fk2/qwn906/4oyqpt
title: mosaic-antarctic-sice16-2022-12.nc

description: :unav
DOI: 10.22008/fk2/qwn906/9thtnr
title: mosaic-antarctic-sice16-2022-11.nc

description: :unav
DOI: 10.22008/fk2/qwn906/tbqlxq
title: mosaic-antarctic-sice16-2023-01.nc

description: :unav
DOI: 10.22008/fk2/qwn906/uxabjs
title: mosaic-antarctic-sice16-2022-10.nc

description: :unav
DOI: 10.22008/fk2/qwn906
title: Antarctica SSA and broadband albedo austral summer 2022/2023 from Sentinel-3’s OLCI and pySICEv1.6

description: Timespan 15 Oct, 2022 to 28 Feb 2023 Description 0.5 km daily SSA and broadband albedo. Albedo is 'spherical', meaning 'white sky' or 'diffuse', i.e. does not depend on the position of the sun. Data format is NetCDF. Embedded are attributes. We suggest using xarray to read the data files. pySICEv1.6 is available at https://github.com/GEUS-SICE/pySICE/releases/tag/v1.6 Related Publications Kokhanovsky, A., M. Lamare, O. Danne, C. Brockmann, M. Dumont, G. Picard, L. Arnaud, V. Favier, B. Jourdain, E. Lemeur, B. Di Mauro, T Aoki, M. Niwano, V. Rozanov, S. Korkin, S. Kipfstuhl, J. Freitag, M. Hoerhold, A. Zuhr, D. Vladimirova, A.-K. Faber, H.C. Steen-Larsen, S. Wahl, J.K. Andersen, B. Vandecrux, D. van As, K.D. Mankoff, M. Kern, E. Zege, and J.E. Box, Retrieval of snow and ice properties from the Sentinel-3 Ocean and Land Colour Instrument, Remote Sensing, Remote Sens. 2019, 11(19), 2280; https://doi.org/10.3390/rs11192280 Kokhanovsky, A.; Box, J.E.; Vandecrux, B.; Mankoff, K.D.; Lamare, M.; Smirnov, A.; Kern, M. The Determination of Snow Albedo from Satellite Measurements Using Fast Atmospheric Correction Technique. Remote Sens. 2020, 12, 234. https://doi.org/10.3390/rs12020234 Arioli, S., Picard, G., Arnaud, L., and Favier, V.: Dynamics of the snow grain size in a windy coastal area of Antarctica from continuous in situ spectral-albedo measurements, The Cryosphere, 17, 2323–2342, https://doi.org/10.5194/tc-17-2323-2023, 2023. Vandecrux, B.; Box, J.E.; Wehrlé, A.; Kokhanovsky, A.A.; Picard, G.; Niwano, M.; Hörhold, M.; Faber, A.-K.; Steen-Larsen, H.C. The Determination of the Snow Optical Grain Diameter and Snowmelt Area on the Greenland Ice Sheet Using Spaceborne Optical Observations. Remote Sens. 2022, 14, 932. https://doi.org/10.3390/rs14040932 Questions? ghislain.picard@univ-grenoble-alpes.fr New pySICE versions Find the latest version of pySICE here: https://github.com/GEUS-SICE/pySICE For example pySICEv2.0 described in Kokhanovsky, A., Vandecrux, B., Wehrlé, A., Danne, O., Brockmann, C., and Box, J. E.: An improved retrieval of snow and Ice properties using spaceborne OLCI/S-3 spectral reflectance measurements: Updated atmospheric correction and snow impurity load estimation, Remote Sens. (Basel), 15, 77, https://doi.org/10.3390/rs15010077, 2022.
DOI: 10.22008/fk2/qwn906/0tpqcw
title: mosaic-antarctic-sice16-2023-02.nc

description: :unav
DOI: 10.15468/bpyuwa
title: First records of Anommatus duodecimstriatus (P.W.J. Müller, 1821) in Canada (Coleoptera, Teredidae)

description: Specimen data to accompany article: Théry T, Ratzlaff C. 2022. First records of Anommatus duodecimstriatus (P.W.J. Müller, 1821) in Canada (Coleoptera, Teredidae). Specimen 2. https://doi.org/10.56222/28166531.2022.2
DOI: 10.5281/zenodo.16708
title: The Manchester Owl Corpus (Mowlcorp), Owl/Xml Serialisation

description: This is the Manchester OWL Corpus (MOWLCorp) in its OWL/XML serialisation.

The files sub-directory contains the actual files. The metadata directory contains csv files with some essential metrics on the ontologies. As can be seen, some files (that were parseable once in the past), were not parseable anymore on the 20th January 2015, due to unloadable imports, or updated parsers that were not backwards compatible. This might mean temporary unavailability, or permanent. A more detailed log can be found in the metadata directory.

Find more information on how to use the corpus, and for what kind of research it might be suitable, on http://mowlrepo.cs.manchester.ac.uk.
DOI: 10.5281/zenodo.8005904
title: Do Repeat Yourself: Understanding Sufficient Conditions for Restricted Chase Non-Termination - Evaluation Material

description: In this archive, we provide the (already normalized and translated) rule sets that we used for the evaluation
of RMFA2, DRPC, and RPC in our paper "Do Repeat Yourself: Understanding Sufficient Conditions for Restricted Chase Non-Termination" at KR 2023. We also provide the raw result files and some basic scripts that we used
to produce and count the results.

Please refer to the provided README.md for more information.
description: Lukas is funded by Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) in project 389792660 (TRR 248, Center for Perspicuous Systems, https://www.perspicuous-computing.science/), by the Bundesministerium für Bildung und Forschung (BMBF, Federal Ministry of Education and Research) under European ITEA project 01IS21084 (InnoSale, Innovating Sales and Planning of Complex Industrial Products Exploiting Artificial Intelligence, https://www.innosale.eu/), by BMBF and DAAD (German Academic Exchange Service) in project 57616814 (SECAI, School of Embedded and Composite AI, https://secai.org), and by the Center for Advancing Electronics Dresden (cfaed).
David is funded by the ANR project CQFD (ANR-18-CE23-0003).
DOI: 10.5281/zenodo.8005905
title: Do Repeat Yourself: Understanding Sufficient Conditions for Restricted Chase Non-Termination - Evaluation Material

description: In this archive, we provide the (already normalized and translated) rule sets that we used for the evaluation
of RMFA2, DRPC, and RPC in our paper "Do Repeat Yourself: Understanding Sufficient Conditions for Restricted Chase Non-Termination" at KR 2023. We also provide the raw result files and some basic scripts that we used
to produce and count the results.

Please refer to the provided README.md for more information.
description: Lukas is funded by Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) in project 389792660 (TRR 248, Center for Perspicuous Systems, https://www.perspicuous-computing.science/), by the Bundesministerium für Bildung und Forschung (BMBF, Federal Ministry of Education and Research) under European ITEA project 01IS21084 (InnoSale, Innovating Sales and Planning of Complex Industrial Products Exploiting Artificial Intelligence, https://www.innosale.eu/), by BMBF and DAAD (German Academic Exchange Service) in project 57616814 (SECAI, School of Embedded and Composite AI, https://secai.org), and by the Center for Advancing Electronics Dresden (cfaed).
David is funded by the ANR project CQFD (ANR-18-CE23-0003).
DOI: 10.5281/zenodo.8348318
title: Genealogy Tarikh al-Tabari: Register

description: This register records the data upon which the "Tarikh al-Tabari Genealogy Project: Visualization and Analysis" is based. The project is still under construction and thus access will be restricted.
DOI: 10.5281/zenodo.10066103
title: Genealogy Tarikh al-Tabari: Register

description: This file is part of the Tarikh al-Tabari Genealogy Project: Visualisation and Analysis. This project is still very much ongoing and will be updated in the future. This file contains the Master's thesis that I've written about this project.
Other uploads within this project
Thesis: https://doi.org/10.5281/zenodo.10066029
Visualisation Genealogy: https://doi.org/10.5281/zenodo.10066053
DOI: 10.5281/zenodo.8348317
title: Genealogy Tarikh al-Tabari: Register

description: This file is part of the Tarikh al-Tabari Genealogy Project: Visualisation and Analysis. This project is still very much ongoing and will be updated in the future. This file contains the Master's thesis that I've written about this project.
Other uploads within this project
Thesis: https://doi.org/10.5281/zenodo.10066029
Visualisation Genealogy: https://doi.org/10.5281/zenodo.10066053
DOI: 10.5281/zenodo.10066105
title: Dataset related to the paper on OncoMPI analysis in urothelial cancer

description: Dataset related to the paper on OncoMPI analysis in urothelial cancer
DOI: 10.5281/zenodo.10066104
title: Dataset related to the paper on OncoMPI analysis in urothelial cancer

description: Dataset related to the paper on OncoMPI analysis in urothelial cancer
DOI: 10.15468/2fu87j
title: First record in Quebec and biological data for Hylota cryptica Klimaszewski & Webster (Coleoptera: Staphylinidae, Aleocharinae)

description: Specimen metadata to accompany publication: Plante E, Théry T. 2022. First record in Quebec and biological data for Hylota cryptica Klimaszewski & Webster (Coleoptera: Staphylinidae, Aleocharinae). Specimen 4. https://doi.org/10.56222/28166531.2022.4
DOI: 10.15468/mb6w25
title: First record of Cephennium thoracicum (P. W. J. Müller & Kunze) for North America and of Cephennium gallicum Ganglbauer for the province of Quebec, Canada (Staphylinidae, Scydmaeninae)

description: Specimen data to accompany publication: Théry T. 2022. First record of Cephennium thoracicum (P. W. J. Müller & Kunze) for North America and of Cephennium gallicum Ganglbauer for the province of Quebec, Canada (Staphylinidae, Scydmaeninae). Specimen 5. https://doi.org/10.56222/28166531.2022.5
DOI: 10.5258/soton/d2807
title: Dataset in support of the Southampton Master of Philosophy thesis 'Airway epithelial cell regulation of T cell responses during viral infection'

description: RT-PCR data for BCI ALI and PBEC ALI (derived from two anonymized Target lung samples) showing expression of RSV-N, CXCL10 and HPRT1 at 2h and 72h post infection with RSV A2 in vitro. Ct values as well as fold change calculations are included for all data included in thesis.
DOI: 10.6084/m9.figshare.24486625
title: Untitled Item

description: Test1
DOI: 10.6084/m9.figshare.24486625.v1
title: Untitled Item

description: Test1
DOI: 10.5281/zenodo.10004382
title: Dynamic Reconstructions of Sagittarius A* with Resolve from 2017 EHT data

description: This repository contains the dynamic reconstructions of Sagittarius A* (SgrA*) from (EHT) data using the Resolve framework, as presented in "Resolving Horizon-Scale Dynamics of Sagittarius A*".
DOI: 10.5281/zenodo.10004381
title: Dynamic Reconstructions of Sagittarius A* with Resolve from 2017 EHT data

description: This repository contains the dynamic reconstructions of Sagittarius A* (SgrA*) from (EHT) data using the Resolve framework, as presented in "Resolving Horizon-Scale Dynamics of Sagittarius A*".
DOI: 10.6084/m9.figshare.23629338
title: Flask and reactor scale production of plant growth regulators by <i>Inonotus hispidus</i>: optimization, immobilization and kinetic parameters

description: The aims of the presented study are to compare submerged, static, and solid-state fermentation in the production of gibberellic acid (GA<sub>3</sub>), indole acetic acid (IAA), and abscisic acid (ABA) by <i>Inonotus hispidus</i>, to optimize with a statistical approach, and to determine the kinetic parameters under flask and reactor conditions. The maximum concentrations of GA<sub>3</sub>, (2478.85 ± 68.53 mg/L), ABA, (273.26 ± 6.17 mg/L) and IAA (30.67 ± 0.19 mg/L) were obtained in submerged conditions. After optimization, these values reached 2998.85 ± 28.85, 339.47 ± 5.50, and 34.56 ± 0.25 mg/L, respectively. Immobilization of fungal cells on synthetic fiber, polyurethane foam, and alginate beads resulted in an increase in plant growth regulators (PGR) production by 5.53%− 5.79% under optimized conditions. At the reactor scale, a significant increase was observed for GA<sub>3</sub> concentration, 5441.54 mg/L, which was 2.14 and 1.45 times higher than non-optimized and optimized conditions in the flask scale, respectively. The maximum values for ABA and IAA were 390.39 and 44.79 mg/L, respectively. Although the specific growth rate (µ) decreases relatively from non-optimized flask conditions to optimized reactor conditions, it was observed that the PGR amounts produced per liter medium (r<sub>p</sub>) and per gram biomass (Q<sub>p</sub>) increased significantly. This is the first report on the synthesis of PGR by <i>Inonotus hispidus</i> which could be crucial for sustainable agriculture.
DOI: 10.5281/zenodo.10066201
title: Advanced Non-Clear Cell Renal Cell Carcinoma Treatments and Survival: A Real-World Single-Centre Experience

description: Dataset of the paper "Advanced Non-Clear Cell Renal Cell Carcinoma Treatments and Survival: A Real-World Single-Centre Experience"
DOI: 10.6084/m9.figshare.23629338.v1
title: Flask and reactor scale production of plant growth regulators by <i>Inonotus hispidus</i>: optimization, immobilization and kinetic parameters

description: The aims of the presented study are to compare submerged, static, and solid-state fermentation in the production of gibberellic acid (GA<sub>3</sub>), indole acetic acid (IAA), and abscisic acid (ABA) by <i>Inonotus hispidus</i>, to optimize with a statistical approach, and to determine the kinetic parameters under flask and reactor conditions. The maximum concentrations of GA<sub>3</sub>, (2478.85 ± 68.53 mg/L), ABA, (273.26 ± 6.17 mg/L) and IAA (30.67 ± 0.19 mg/L) were obtained in submerged conditions. After optimization, these values reached 2998.85 ± 28.85, 339.47 ± 5.50, and 34.56 ± 0.25 mg/L, respectively. Immobilization of fungal cells on synthetic fiber, polyurethane foam, and alginate beads resulted in an increase in plant growth regulators (PGR) production by 5.53%− 5.79% under optimized conditions. At the reactor scale, a significant increase was observed for GA<sub>3</sub> concentration, 5441.54 mg/L, which was 2.14 and 1.45 times higher than non-optimized and optimized conditions in the flask scale, respectively. The maximum values for ABA and IAA were 390.39 and 44.79 mg/L, respectively. Although the specific growth rate (µ) decreases relatively from non-optimized flask conditions to optimized reactor conditions, it was observed that the PGR amounts produced per liter medium (r<sub>p</sub>) and per gram biomass (Q<sub>p</sub>) increased significantly. This is the first report on the synthesis of PGR by <i>Inonotus hispidus</i> which could be crucial for sustainable agriculture.