cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.5668756.v1
title: An automatic gain control circuit to improve ECG acquisition

description: Abstract Introduction Long-term electrocardiogram (ECG) recordings are widely employed to assist the diagnosis of cardiac and sleep disorders. However, variability of ECG amplitude during the recordings hampers the detection of QRS complexes by algorithms. This work presents a simple electronic circuit to automatically normalize the ECG amplitude, improving its sampling by analog to digital converters (ADCs). Methods The proposed circuit consists of an analog divider that normalizes the ECG amplitude using its absolute peak value as reference. The reference value is obtained by means of a full-wave rectifier and a peak voltage detector. The circuit and tasks of its different stages are described. Results Example of the circuit performance for a bradycardia ECG signal (40bpm) is presented; the signal has its amplitude suddenly halved, and later, restored. The signal is automatically normalized after 5 heart beats for the amplitude drop. For the amplitude increase, the signal is promptly normalized. Conclusion The proposed circuit adjusts the ECG amplitude to the input voltage range of ADC, avoiding signal to noise ratio degradation of the sampled waveform in order to allow a better performance of processing algorithms.
DOI: 10.6084/m9.figshare.5668753
title: Differentiation of free-ranging chicken using discriminant analysis of phenotypic traits

description: ABSTRACT In this study, we investigated the differentiation of five different chicken ecotypes - Center, North, South, West, and East - of Saudi Arabia using discriminate analysis. The analysis was based on nine important morphological and phenotypic traits: body color, beak color, earlobe color, eye color, shank color, comb color, comb type, comb size, and feather distribution. There was a strong significant relationship between the phenotype and effect of geographic height in terms of comb type and earlobe color in males as well as body, beak, eye, and shank color. In particular, the comb type and earlobe color differentiated the ecotypes of males. Among the females, the beak, earlobe, eye, shank color, and feather distribution had more differentiating power. Moreover, the discriminant analysis revealed that the five ecotypes were grouped into three clusters; the Center and the North in one cluster, the West and the South ecotypes in the second for males, and the East ecotype in the last cluster. The female dendogram branching was similar to the male dendrogram branching, except that the Center ecotype was grouped with the North instead of the South. The East ecotype was highly discriminated from the other ecotypes. Nevertheless, the potential of recent individual migration between ecotypes was also noted. Accordingly, the results of the utilized traits in this study might be effective in characterization and conservation of the genetic resources of the Saudi chicken.
DOI: 10.6084/m9.figshare.5668753.v1
title: Differentiation of free-ranging chicken using discriminant analysis of phenotypic traits

description: ABSTRACT In this study, we investigated the differentiation of five different chicken ecotypes - Center, North, South, West, and East - of Saudi Arabia using discriminate analysis. The analysis was based on nine important morphological and phenotypic traits: body color, beak color, earlobe color, eye color, shank color, comb color, comb type, comb size, and feather distribution. There was a strong significant relationship between the phenotype and effect of geographic height in terms of comb type and earlobe color in males as well as body, beak, eye, and shank color. In particular, the comb type and earlobe color differentiated the ecotypes of males. Among the females, the beak, earlobe, eye, shank color, and feather distribution had more differentiating power. Moreover, the discriminant analysis revealed that the five ecotypes were grouped into three clusters; the Center and the North in one cluster, the West and the South ecotypes in the second for males, and the East ecotype in the last cluster. The female dendogram branching was similar to the male dendrogram branching, except that the Center ecotype was grouped with the North instead of the South. The East ecotype was highly discriminated from the other ecotypes. Nevertheless, the potential of recent individual migration between ecotypes was also noted. Accordingly, the results of the utilized traits in this study might be effective in characterization and conservation of the genetic resources of the Saudi chicken.
DOI: 10.6084/m9.figshare.5668747
title: In Vitro Evaluation of the Remineralizing Potential and Antimicrobial Activity of a Cariostatic Agent with Silver Nanoparticles

description: Abstract Cariostatic treatment has been shown to successfully arrest caries. However, it blackens the carious tooth structure. This study evaluated the effects of an experimental cariostatic agent with silver nanoparticles (Ag-Nano) using microhardness (MH) and microbiological tests. The cariostatic agents tested were: Saforide®, Cariestop®, Ancarie® and Ag-Nano. Sixty-six samples from deciduous enamel were submitted to initial (after pH cycling to obtain initial caries-like lesion) and final (after cariostatic application) MH testing and %MH values were calculated. After longitudinal sectioning, internal (I) MH was evaluated. Strains of Streptococcus mutans, Escherichia coli, and Enterococcus faecalis in brain-heart infusion culture were treated with the cariostatic agents. Agar diffusion tests (ADTs) were performed and minimum inhibitory concentrations were determined. The statistical tests used were: Kruskal-Wallis and Dunn (%MD; ADT; MIC) and ANOVA followed by Tukey’s test (I-MH) (p&lt;0.05). The %MH of Saforide® was significantly greater than that of Ag-Nano (p&lt;0.05). Internal MH showed progressive improvement in the enamel remineralization for all cariostatic tested. In ADTs showed greater inhibition of S. mutans, E. faecalis, and E. coli by Saforide® than by Ancarie® and Ag-Nano. Ag-Nano was able to inhibit 100% microorganism growth at a lower concentration than required for the other agents. It was concluded that Ag-Nano treatment promoted remineralization of deciduous tooth enamel with initial caries-like lesion and bactericidal activity.
DOI: 10.6084/m9.figshare.5668744
title: Oral cancer stem cells - properties and consequences

description: Abstract Research on cancer stem cells (CSCs) has greatly increased in the field of medicine and pathology; however, some conceptual misunderstandings are still present among the public as well as within the general scientific community that is not yet familiar with the subject. The very first problem is the misinterpretation of CSCs as a synonym of their normal counterparts, the well-known stem cells (SCs). Particularly in Dentistry, another common mistake is the misinterpretation of oral CSCs as normal tooth-derived SCs. The present review aims to clarify important concepts related to normal SCs and CSCs, as well as discuss the relevance of CSCs to the development, metastasis and therapy resistance of oral squamous cell carcinoma.
DOI: 10.6084/m9.figshare.5668744.v1
title: Oral cancer stem cells - properties and consequences

description: Abstract Research on cancer stem cells (CSCs) has greatly increased in the field of medicine and pathology; however, some conceptual misunderstandings are still present among the public as well as within the general scientific community that is not yet familiar with the subject. The very first problem is the misinterpretation of CSCs as a synonym of their normal counterparts, the well-known stem cells (SCs). Particularly in Dentistry, another common mistake is the misinterpretation of oral CSCs as normal tooth-derived SCs. The present review aims to clarify important concepts related to normal SCs and CSCs, as well as discuss the relevance of CSCs to the development, metastasis and therapy resistance of oral squamous cell carcinoma.
DOI: 10.6084/m9.figshare.5668741
title: Hormesis Effect of Herbicides Subdoses on Submerged Macrophytes in Microassay Conditions

description: ABSTRACT: The goal of the study was to evaluate the effect of 2.4-D and clomazone doses on the growth of the submerged macrophytes Egeria densa and E. najas, in microassay conditions. Therefore, tests were conducted in a bioassay room at the temperature of 27.0 ± 2.0 °C, photoperiod of 24 light hours and illumination of 500 lux. The apical fragments (shoot tips) of the macrophytes with 5.0 cm of length were transferred to test tubes with a 100 mL capacity, containing 70 mL of water. The tested concentrations were: 0.1; 1.0; 3.5; 11.2; 36.5; and 118.0 mg L-1 and a control sample with seven replications. In the test with 2.4-D on E. densa, in the control sample treatment and the 0.1 mg L-1 treatment there was shorter length: at 1.0; 3.5; 11.2; 36.5 and 118.0 mg L-1 there was a relative increase of 90.6; 96.3; 91.6; 86.5 and 58.8%, demonstrating growth stimulation. E. najas behavior was similar to that of E. densa. In the test with clomazone for E. densa, the greatest length occurred in the control sample treatment. At the concentrations of 0.1; 1.0; 3.5; 11.2; 36.5 and 118.0 mg L-1, there was relative growth of -25.8; -26.4; -31.7; -28.4; -37.7 and -45.0% respectively, showing herbicidal effect on the plants. E. najas behavior was similar, with lower growth at 11.2, 36.5 and 118.0 mg L-1. Sub-doses of the herbicide 2.4-D cause growth stimulation (Hormesis effect) in E. densa and E. najas, while clomazone causes herbicidal effect.
DOI: 10.6084/m9.figshare.5668741.v1
title: Hormesis Effect of Herbicides Subdoses on Submerged Macrophytes in Microassay Conditions

description: ABSTRACT: The goal of the study was to evaluate the effect of 2.4-D and clomazone doses on the growth of the submerged macrophytes Egeria densa and E. najas, in microassay conditions. Therefore, tests were conducted in a bioassay room at the temperature of 27.0 ± 2.0 °C, photoperiod of 24 light hours and illumination of 500 lux. The apical fragments (shoot tips) of the macrophytes with 5.0 cm of length were transferred to test tubes with a 100 mL capacity, containing 70 mL of water. The tested concentrations were: 0.1; 1.0; 3.5; 11.2; 36.5; and 118.0 mg L-1 and a control sample with seven replications. In the test with 2.4-D on E. densa, in the control sample treatment and the 0.1 mg L-1 treatment there was shorter length: at 1.0; 3.5; 11.2; 36.5 and 118.0 mg L-1 there was a relative increase of 90.6; 96.3; 91.6; 86.5 and 58.8%, demonstrating growth stimulation. E. najas behavior was similar to that of E. densa. In the test with clomazone for E. densa, the greatest length occurred in the control sample treatment. At the concentrations of 0.1; 1.0; 3.5; 11.2; 36.5 and 118.0 mg L-1, there was relative growth of -25.8; -26.4; -31.7; -28.4; -37.7 and -45.0% respectively, showing herbicidal effect on the plants. E. najas behavior was similar, with lower growth at 11.2, 36.5 and 118.0 mg L-1. Sub-doses of the herbicide 2.4-D cause growth stimulation (Hormesis effect) in E. densa and E. najas, while clomazone causes herbicidal effect.
DOI: 10.6084/m9.figshare.5668738
title: Crop Growth and Yield Losses in Wheat Due to Little Seed Canary Grass Infestation Differ with Weed Densities and Changes in Environment

description: ABSTRACT: Understanding the weed interference with different sowing times of crop is inevitable for forecasting yield losses by weed infestation and designing sustainable weed management systems. A field experiment was carried out to evaluate the effects of sowing dates (20th November, 10th December) and various little seed canary grass (LCG) infestation levels (10, 20, 30 and 40 plant m-2) on growth and yield of wheat under semiarid conditions. Plots with two natural infestations of weeds including LCG (Unweeded control; UWC) and excluding LCG (UWC-LCG) were maintained for comparing its interference in pure stands with designated densities. A season-long weed-free (WFC) treatment was also run. All the weeds/LCG infestation levels starting from 10 LCG plants m-2 considerably reduced the wheat growth (leaf area index, crop growth rate, total dry matter accumulation) and hampered the yield contributing factors in both sowing dates. Presence of LCG was more detrimental for growth of late-sown wheat (10th Dec), therefore, 40 LCG plants m-2 recorded more reductions in growth indices of wheat even than UWC. In late sown wheat crop, the grain yield losses by 40 LCG plants m-2 and UWC were comparable, however, these losses were much greater than UWC LCG. In crux, delay in sowing of wheat not only reduced the crop growth and yield but also enhanced the LCG/weed interference. Furthermore, greater competitive ability of LCG particularly for late-sown wheat suggests that it should be controlled in order to provide healthy environment for crop plants.
DOI: 10.6084/m9.figshare.5668738.v1
title: Crop Growth and Yield Losses in Wheat Due to Little Seed Canary Grass Infestation Differ with Weed Densities and Changes in Environment

description: ABSTRACT: Understanding the weed interference with different sowing times of crop is inevitable for forecasting yield losses by weed infestation and designing sustainable weed management systems. A field experiment was carried out to evaluate the effects of sowing dates (20th November, 10th December) and various little seed canary grass (LCG) infestation levels (10, 20, 30 and 40 plant m-2) on growth and yield of wheat under semiarid conditions. Plots with two natural infestations of weeds including LCG (Unweeded control; UWC) and excluding LCG (UWC-LCG) were maintained for comparing its interference in pure stands with designated densities. A season-long weed-free (WFC) treatment was also run. All the weeds/LCG infestation levels starting from 10 LCG plants m-2 considerably reduced the wheat growth (leaf area index, crop growth rate, total dry matter accumulation) and hampered the yield contributing factors in both sowing dates. Presence of LCG was more detrimental for growth of late-sown wheat (10th Dec), therefore, 40 LCG plants m-2 recorded more reductions in growth indices of wheat even than UWC. In late sown wheat crop, the grain yield losses by 40 LCG plants m-2 and UWC were comparable, however, these losses were much greater than UWC LCG. In crux, delay in sowing of wheat not only reduced the crop growth and yield but also enhanced the LCG/weed interference. Furthermore, greater competitive ability of LCG particularly for late-sown wheat suggests that it should be controlled in order to provide healthy environment for crop plants.
DOI: 10.6084/m9.figshare.5668732
title: Selectivity of Chlorimuron-Ethyl to Castorbean Crops

description: ABSTRACT: Castorbean presents high sensitivity to competition; therefore, it is necessary to develop alternatives for the weed management, mainly for the chemical control of eudicotyledons species. The goal of this work was to evaluate the selectivity of chlorimuron-ethyl to castorbean crops in different development stages. Four experiments differentiated by the genetic material were conducted: Lyra, Íris and Savana hybrids and AL Guarany 2002 cultivar. The treatments corresponded to the application conditions of chlorimuron-ethyl [sample control with no application, doses of 15 e 20 g a.i. ha-1 with the formulations Classic™ and Clorimuron Master Nortox™] in two phenological crop stages (4 to 5 and 7 to 8 true leaf stages). The experimental design was in randomized blocks with four replications, in a factorial scheme of 5 x 2 (herbicide and application stage). The intoxication was more severe for the 7 to 8 leaf stage and with the dose of 20 g ha-1 on day 7 days after application (DAA); there were plant recovery and mild symptoms on day 21 DAA, especially for the 4 to 5 leaf stage. The yield was reduced with the 20 g ha-1 dose for Lyra hybrid with both formulations and for Savana castorbean, only with the Classic™ formulation. The chlorimuron-ethyl herbicide, at 15 g ha-1, showed selectivity to castorbean, regardless of the stage application (4 to 5 or 7 to 8 leaves).
DOI: 10.6084/m9.figshare.5668732.v1
title: Selectivity of Chlorimuron-Ethyl to Castorbean Crops

description: ABSTRACT: Castorbean presents high sensitivity to competition; therefore, it is necessary to develop alternatives for the weed management, mainly for the chemical control of eudicotyledons species. The goal of this work was to evaluate the selectivity of chlorimuron-ethyl to castorbean crops in different development stages. Four experiments differentiated by the genetic material were conducted: Lyra, Íris and Savana hybrids and AL Guarany 2002 cultivar. The treatments corresponded to the application conditions of chlorimuron-ethyl [sample control with no application, doses of 15 e 20 g a.i. ha-1 with the formulations Classic™ and Clorimuron Master Nortox™] in two phenological crop stages (4 to 5 and 7 to 8 true leaf stages). The experimental design was in randomized blocks with four replications, in a factorial scheme of 5 x 2 (herbicide and application stage). The intoxication was more severe for the 7 to 8 leaf stage and with the dose of 20 g ha-1 on day 7 days after application (DAA); there were plant recovery and mild symptoms on day 21 DAA, especially for the 4 to 5 leaf stage. The yield was reduced with the 20 g ha-1 dose for Lyra hybrid with both formulations and for Savana castorbean, only with the Classic™ formulation. The chlorimuron-ethyl herbicide, at 15 g ha-1, showed selectivity to castorbean, regardless of the stage application (4 to 5 or 7 to 8 leaves).
DOI: 10.6084/m9.figshare.5668729
title: Biological Control of Charcoal Rot of Mungbean by Trichoderma harzianum and Shoot Dry Biomass of Sisymbrium irio

description: ABSTRACT: A pot experiment was carried out for the biological control of charcoal rot on mung bean (Vigna radiata), caused by Macrophomina phaseolina. Pot soil was made sick with an inoculum of M. phaseolina. Dried powdered leaves of Sisymbrium irio, a weed from the Brassicaceae family, were mixed in soil at 1, 2 and 3% (w/w) with and without the application of Trichoderma harzianm, a fungal biological control agent. The highest grain yield (3.62 g pot-1) was recorded in a combined application of T. harzianum and 1% S. irio leaf amendment, which was 62% and 805% higher than negative and positive control treatments, respectively. The application of S. irio leaf amendment and T. harzianum generally enhanced leaf protein, sugar and chlorophyll contents, and catalase activity. This study concludes that T. harzianum in combination with 1% dry leaves of S. irio as a soil amendment can be used to achieve the best grain yield under biotic stress of M. phaseolina.
DOI: 10.6084/m9.figshare.5668726
title: Protective Effect on Eucalyptus Plants and Signal Grass Control with a Tank Mixture of Glyphosate and Liquid fertilizer

description: ABSTRACT: What is expected from an effective antidote, applied with an herbicide, is that it protects crops from damages by the herbicide without reducing its action on weeds. In this context, the goal of this study was to evaluate the effect of liquid fertilizer as a protector of eucalyptus plants and to control signal grass (Urochloa brizantha) submitted the application of glyphosate when applied in tank mixture. Plants were submitted to doses of liquid fertilizer and glyphosate; the application was performed so that the syrup would reach all aerial parts of the plants. The intoxication percentage of eucalyptus plants was evaluated on day 14, 35 and 49 after application (DAA). On day 49 DAA, the morphologic parameters of eucalyptus plants and the dry mass of signal grass were evaluated. The increase in glyphosate doses reduced the dry mass of signal grass, and 1,080 g ha-1 of glyphosate caused the death of the plant, regardless of the use of the liquid fertilizer. At 90, 180, 360 and 540 g ha-1 doses of glyphosate, the mixing tank with liquid fertilizer reduced glyphosate damages to signal grass. Higher doses of glyphosate caused greater toxicity in eucalyptus and the use of liquid fertilizer reduced this poisoning. High doses of glyphosate increased the control of signal grass, but they also increased the damages to eucalyptus, and the liquid fertilizer tends to reduce such damage. The tank mixture of glyphosate + liquid fertilizer (540 g ha-1 + 3 L ha-1) controlled signal grass without causing damages to eucalyptus.
DOI: 10.6084/m9.figshare.5668726.v1
title: Protective Effect on Eucalyptus Plants and Signal Grass Control with a Tank Mixture of Glyphosate and Liquid fertilizer

description: ABSTRACT: What is expected from an effective antidote, applied with an herbicide, is that it protects crops from damages by the herbicide without reducing its action on weeds. In this context, the goal of this study was to evaluate the effect of liquid fertilizer as a protector of eucalyptus plants and to control signal grass (Urochloa brizantha) submitted the application of glyphosate when applied in tank mixture. Plants were submitted to doses of liquid fertilizer and glyphosate; the application was performed so that the syrup would reach all aerial parts of the plants. The intoxication percentage of eucalyptus plants was evaluated on day 14, 35 and 49 after application (DAA). On day 49 DAA, the morphologic parameters of eucalyptus plants and the dry mass of signal grass were evaluated. The increase in glyphosate doses reduced the dry mass of signal grass, and 1,080 g ha-1 of glyphosate caused the death of the plant, regardless of the use of the liquid fertilizer. At 90, 180, 360 and 540 g ha-1 doses of glyphosate, the mixing tank with liquid fertilizer reduced glyphosate damages to signal grass. Higher doses of glyphosate caused greater toxicity in eucalyptus and the use of liquid fertilizer reduced this poisoning. High doses of glyphosate increased the control of signal grass, but they also increased the damages to eucalyptus, and the liquid fertilizer tends to reduce such damage. The tank mixture of glyphosate + liquid fertilizer (540 g ha-1 + 3 L ha-1) controlled signal grass without causing damages to eucalyptus.
DOI: 10.6084/m9.figshare.5668720
title: Topical application of bFGF on acid-conditioned and non-conditioned dentin: effect on cell proliferation and gene expression in cells relevant for periodontal regeneration

description: Abstract Periodontal regeneration is still a challenge in terms of predictability and magnitude of effect. In this study we assess the biological effects of combining chemical root conditioning and biological mediators on three relevant cell types for periodontal regeneration. Material and Methods: Bovine dentin slices were conditioned with 25% citric acid followed by topical application of basic fibroblast growth factor (bFGF, 10 and 50 ng). We used ELISA to assess the dynamics of bFGF release from the dentin surface and RT-qPCR to study the expression of Runx2, Col1a1, Bglap and fibronectin by periodontal ligament (PDL) fibroblasts, cementoblasts and bone marrow stromal cells (BMSC) grown onto these dentin slices. We also assessed the effects of topical application of bFGF on cell proliferation by quantification of genomic DNA. Results: Acid conditioning significantly increased the release of bFGF from dentin slices. Overall, bFGF application significantly (p&lt;0.05) increased cell proliferation, except for BMSC grown on non-conditioned dentin slices. Dentin substrate discretely increased expression of Col1a1 in all cell types. Expression of Runx2, Col1a1 and Fn was either unaffected or inhibited by bFGF application in all cell types. We could not detect expression of the target genes on BMSC grown onto conditioned dentin. Conclusion: Acid conditioning of dentin improves the release of topically-applied bFGF. Topical application of bFGF had a stimulatory effect on proliferation of PDL fibroblasts, cementoblasts and BMSC, but did not affect expression of Runx2, Col1a1, Bglap and fibronectin by these cells.