cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.22140596.v1
title: Supplementary Material for: The Effect of Preoperative Tamsulosin on Ureteral Navigation, Operation, and Safety: A Systematic Review and Meta-Analysis

description: <b><i>Introduction:</i></b> Urolithiasis is one of the most common diseases in the world, and at present, ureteroscopy (URS) is the first choice for its treatment. Although the effect is good, there is a risk of insertion failure of ureteroscope. Tamsulosin, as an α-receptor blocker, has the function of relaxing ureteral muscles, and can help stones to be discharged from ureteral orifice. In this study, we aimed to determine the effect of preoperative tamsulosin on ureteral navigation, operation, and safety. <b><i>Methods:</i></b> This study was conducted and reported according to the meta-analysis extension of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). The PubMed and Embase databases were searched for studies. Data were extracted according to the PRISMA principles. We collected and combined randomized controlled trial and researches in reviews of preoperative tamsulosin to explore the effect of preoperative tamsulosin on ureteral navigation, operation, and safety. A data synthesis was performed using RevMan 5.4.1 software (Cochrane). Heterogeneity was mainly evaluated with I2 tests. Key metrics include: success rate of ureteral navigation, time of URS, stone-free rate, and postoperative symptoms. <b><i>Result:</i></b> We summarized and analyzed 6 studies. We noted a statistically significant improvement in the success rate of ureteral navigation (Mantel-Haenszel [M-H], odds ratio [OR]: 3.78, 95% confidence interval [CI]: [2.34, 6.12], <i>p</i> &lt; 0.01) and stone-free rate (M-H, OR: 2.25, 95% CI: [1.16, 4.36], <i>p</i> = 0.02) with tamsulosin preoperatively. At the same time, we also observed that postoperative fever (M-H, OR: 0.37, 95% CI: [0.16, 0.89], <i>p</i> = 0.03) and postoperative analgesia (M-H, OR: 0.21, 95% CI: [0.05, 0.92], <i>p</i> = 0.04) were also reduced because of preoperative tamsulosin. <b><i>Conclusion:</i></b> Preoperative tamsulosin can not only increase the one-time success rate of ureteral navigation and the stone-free rate of URS but also reduce the incidence of postoperative adverse symptoms such as postoperative fever and postoperative pain.
DOI: 10.6084/m9.figshare.26149414.v3
title: Rebuilding Investigations Kit

description: Investigations of healthcare harm often overlook the valuable insights of patients and families.An initial research phase of this study reviewed literature, interviewed stakeholders (patients and families, staff who have been investigated and those who have conducted investigations, policy makers, patient safety researchers), and conducted a documentary analysis of policy statements for half the NHS Trusts in England and Wales. The findings from this research were complex, but communication of these findings was further complicated by issues of trust. Patients and families had experienced harm from initial healthcare, and then secondary harms from poor investigation processes. This activity was developed as a sense making activity that synthesises the evidence from the mixed methods research phase. Rather than telling people what the researchers found from the evidence, this activity enabled others to come to their own conclusions.It is based on an interactive narrative, that presents multiple perspectives of a serious incident. The narrative unfolds in three stages of [1] past (the initial incident or harm event), [2] present (the investigation) and [3] future (the aftermath or longer term impacts on the characters in the narrative). The narrative is told through a series of cards. The cards initial reveal the characters involved in the narrative, who are arranged on the narrative timeline, where each character has their own timeline of events. Subsequent cards reveal these events, and the person engaging in the activity arranges them in an appropriate order on an appropriate character timeline.The narrative is fragmented so the person engaging in this activity kit must piece together the story from the fragments to make sense of it. In phase 2, the person engaging in this activity is then cast into an active role in the narrative as the incident investigator. They make choices about who they are as an investigator and gain access to different kinds of evidence.This is repeated, the second time as a different investigator.In the concluding part of this narrative, the person engaging in the activity finds out what the longer term impacts of the incident and the investigation have been in different characters in the narrative. <br>https://learn-together.org.uk/
DOI: 10.17044/scilifelab.28746086.v1
title: The BalticMAG catalog

description: This is a comprehensive catalog of species-cluster representative genomes. To make this catalog, we generated 527 metagenome-assembled genomes (MAGs) from 204 microbial model communities. Moreover, we binned 305 MAGs from the metagenomes corresponding to the samples from which we established the microbial model communities. To make the genomic catalog comprehensive, we added 771 MAGs from the publicly available metagenomes collected from the Baltic Sea (Alneberg et al., 2018, 2020). Altogether, the 1603 MAGs were dereplicated into 701 species-clusters (average nucleotide identity - ANI ≥ 95%), which form the Baltic Sea genomic catalog (BalticMAG catalog).In this Figshare, we share all 701 species-cluster representative genomes. Moreover, you will find a table with metadata for the genomes.
DOI: 10.6084/m9.figshare.18070597.v1
title: Additional file 13 of Integrative analysis of 3604 GWAS reveals multiple novel cell type-specific regulatory associations

description: Additional file 13: Table S12. FORGE2 DNase I hotspot analysis results (q-values) for a set of 25 variants from a GWAS on myeloproliferative neoplasms.
DOI: 10.6084/m9.figshare.26977276.v1
title: Supplementary Material for: Effectiveness of Intranasal Corticosteroids for Sleep Disturbances in Patients with Allergic Rhinitis: A Systematic Review and Meta-Analysis

description: Introduction: Allergic rhinitis (AR) is a chronic condition caused by an immunoglobulin E-mediated response to environmental allergens, which affects 10–40% of the global population. AR symptoms, such as nasal congestion and rhinorrhea, significantly reduce quality of life and are associated with sleep disturbances, further exacerbating the condition's burden. Despite the known impact of AR on sleep, the effects of intranasal corticosteroids on sleep quality have not been comprehensively reviewed. Therefore, this systematic review and meta-analysis aimed to investigate the efficacy of intranasal corticosteroids in improving sleep quality among patients with AR.
Methods: This systematic review and meta-analysis followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. The study protocol was registered with PROSPERO (CRD42023460698). A comprehensive search was conducted on PubMed, Cochrane Central Register of Controlled Trials, and Ichushi-Web. Randomized controlled trials (RCTs) comparing intranasal corticosteroids with placebos in patients with AR were included. Data extraction and risk of bias assessment were independently performed by two authors. The primary outcome was the improvement in sleep quality measured by standardized questionnaires. Meta-analyses were performed using a random-effects model. The risk of bias was assessed using the RoB2 tool.
Results: Eighteen RCTs involving 6,019 participants were included. The meta-analysis of 12 comparisons from eight studies for the Rhinoconjunctivitis Quality of Life Questionnaire sleep domain showed significant improvement in sleep quality with a standardized mean difference (SMD) of 0.292 (95% confidence interval [CI]: 0.235 to 0.350, p &lt; 0.0001, I² = 0.0%). The Nocturnal Rhinoconjunctivitis Quality of Life Questionnaire also showed improvement with an SMD of 0.284 (95% CI: 0.164 to 0.404, p &lt; 0.0001) based on two comparisons from one study. However, the Epworth Sleepiness Scale did not show significant results (SMD: 0.027, 95% CI: -0.429 to 0.483, p = 0.907) based on two comparisons from two studies. Sensitivity analysis, excluding two studies with high risk of bias according to RoB2, confirmed the robustness of these results. Subgroup analyses for patients with seasonal or perennial AR showed significant improvements in both groups.
Conclusion: This study demonstrates that intranasal corticosteroids significantly improve sleep quality in patients with AR. These findings support the use of intranasal corticosteroids as a first-line treatment for AR, not only for managing daytime symptoms but also for enhancing sleep quality. Future research should focus on sleep quality changes as a primary outcome and incorporate both subjective and objective measures to better understand the relationship between sleep and AR symptoms.
DOI: 10.6084/m9.figshare.28703024.v1
title: Source data of "SMART-BarSeq: Multiplexed Metabolic Profiling via aTF-Nanopore Sequencing Enables Clinical Biomarker Detection"

description: Source data of "SMART-BarSeq: Multiplexed Metabolic Profiling via aTF-Nanopore Sequencing Enables Clinical Biomarker Detection"
DOI: 10.6084/m9.figshare.25466395.v1
title: Data from: Questioning the sixth mass extinction

description: <b>Abstract</b>The idea that Earth is currently experiencing a sixth mass extinction is widespread. We critically evaluate this claim. Very few studies have tested this idea. Some studies showed that recent extinction rates are faster than fossil background rates, but extinction rates can exceed background rates outside mass extinctions. Other studies extrapolated from recent extinctions to project 75% global species loss. But these recent extinctions were mostly of island species. No cause was specified for these future extinctions, and &gt;50% of assessed species are considered non-threatened. We find numerous other issues. Proponents of the sixth mass extinction have made invaluable contributions by highlighting recent extinctions, but these extinctions may not be equivalent to past mass extinctions or relevant to current threats.
DOI: 10.6084/m9.figshare.25840936.v1
title: Charlie's Place Lichen Data

description: These data describe in-depth lichen collections in various habitats in the area of central Newfoundland known as "Charlie's Place". These collections are describe in a manuscript by Gillingham et al. published in the Bryologist. NOTE: CollectionID/Foray Number: specimens in this column starting with "CMS" are part of the Foray NL (2023); other collector numbers beginning with "CH" are collections by Claudia Hanel (Province of NL); all other numbers are collector number by R. Troy McMullin (Canadian Museum of Nature)<br>
DOI: 10.6084/m9.figshare.19158146.v1
title: Evaluation of alternatives and decision matrix.docx

description: This file contain information about expert evaluations of Azerbaijan regions according to the criteria
DOI: 10.6084/m9.figshare.25834897.v1
title: Supplementary Material for: An unusual presentation of MPO-associated glomerulonephritis and suspected IgA mediated anti-GBM disease: a case report

description: Introduction: Anti-glomerular basement membrane (GBM) disease is a rare cause of glomerulonephritis usually mediated by IgG antibodies and is associated with ANCA-associated glomerulonephritis in up to 50% of cases. IgA mediated anti-GBM disease is extremely rare and presents diagnostic difficulties as circulating IgA antibodies will not be detected by standard serological tests for anti-GBM disease. 
Case presentation: We present the case of a 67 year old man with rapidly progressive glomerulonephritis requiring haemodialysis at presentation. Serological testing was positive for anti-MPO and negative for IgG anti-GBM antibodies. Kidney biopsy revealed necrotizing crescentic glomerulonephritis with linear staining of IgA along the GBM. He was treated with a combination of immunosuppression and plasma exchange and was able to become dialysis independent. 
Conclusion: To our knowledge, this is the first documented “double positive” IgA anti-GBM disease and ANCA-associated glomerulonephritis.
DOI: 10.6084/m9.figshare.6489353.v1
title: aacna_rtqpcr

description: CT values of RTqPCR
DOI: 10.6084/m9.figshare.25567248.v1
title: Supplementary Material for: Additive Effects of Citrus Juice Flavonoid Naringenin and Statins on HERG Channels Expressed in Xenopus Oocytes

description: Objective: Naringenin, a major flavonoid found in citrus juice, has been shown to inhibit HERG channels and cause QT prolongation. Statins, the most commonly used class of cholesterol reducing drugs, have also been reported to inhibit HERG channels and prolong QT interval in patients using these drugs. However, the interaction between naringenin and statins on the function of HERG channels has not been studied. Materials and Methods: In the present study, we expressed HERG channels in Xenopus oocytes and tested the effects of naringenin and statins separately and combined on HERG channels. Results: When 30 µM naringenin was added to statins (1 µM rosuvastatin or 3 µM atorvastatin), significantly greater inhibition of HERG was demonstrated, compared to the inhibition caused by statins alone. Conclusions: The results indicate that an additive interaction occurs between naringenin and statins; this could pose an increased risk of arrhythmias by decreasing repolarization reserve.
DOI: 10.6084/m9.figshare.28789940.v1
title: Fig6_Sleep

description: Raw and processed data
DOI: 10.6084/m9.figshare.12198510.v14
title: CINDy Networks from TCGA

description: Networks of CINDy interactions (between modulators and transcription factors) generated by the algorithm described here: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0109569. <br>The R objects are intended to be loaded and used in conjunction with the MOMA package here: https://bioconductor.org/packages/devel/bioc/html/MOMA.html
DOI: 10.6084/m9.figshare.14544621.v1
title: Open-ended Questionnaire Responses-Social Cyncisim-converted.pdf

description: A qualitative study to investigate social cynicism in women in a sample of (n=20) young adult women through a focus group discussion and open-ended questionnaires. The data was analyzed by applying thematic analysis that generated five central themes.
DOI: 10.6084/m9.figshare.4665061.v1
title: Bathymetry of the Adriatic Sea The legacy of the last eustatic cycle and the impact of modern sediment dispersal

description: The Istituto di Scienze Marine (ISMAR-CNR) has conducted several research projects on the Italian side of the Adriatic Sea over more than 15 years, collecting bathymetric, geophysical and sediment core data to perform multidisciplinary studies of modern sediment dynamics and of past environmental changes during the last eustatic cycle. A crucial step in this direction was the construction of a detailed bathymetry, a time-consuming task due to the extensive shallow water portion of the basin. Given the setting of the Adriatic Sea and the long-lasting research effort, the bathymetric map is necessarily based on heterogeneous data with uneven spatial distribution of Single-Beam echo-soundings. The main objective of this work is to illustrate the methodology applied to compile the bathymetric map of the west side of the Adriatic Sea at basin scale (1:750,000) and to describe the main morphological units that characterise the seafloor and reflect its main geological features. This bathymetry can also be used in oceanographic modelling both at regional and local scale, focussing on the interaction between bottom currents and seafloor morphology.<br>
DOI: 10.5281/zenodo.15299980
title: DS1.1 - Simulation transmission studies of assessing transmission performance of VCSEL-based transmitters across temperature variations and fiber lengths_SPRINTER_v2.0

description: The dataset consists of simulated waveforms and eye diagrams captured at both transmitter (Tx) and receiver (Rx) ends, aiming to assess transmission performance across various operational temperatures of the vertical-cavity surface-emitting laser (VCSEL)-based Tx (25, 55, and 85 °C). 

Specifically, at the Tx-end, the simulation data are enhanced with captured spectra at the VCSEL-based Tx output. For each temperature, the peak-to-peak voltage of the RF electrical input was set at 200 mV, operating at 50 GBaud with an OOK-NRZ modulation format. This peak-to-peak voltage was selected in order to align with the performance of a typical network interface controller. In addition, the chirp factor of the VCSEL-based Tx was set at 10 and 12.

Following this, the transmission performance was examined across fiber lengths of 500 m and 1 km. The exported data focused on capturing the simulation results at three critical stages of the transmission: a) during the generation of the RF 50 GBaud OOK-NRZ signals, b) at the VCSEL output, and c) during the reception of the electrical signal at the Rx-end (transimpedance amplifier (TIA) output). The devices that impose the bandwidth limitations and are investigated in these simulations, were: the laser driver, VCSEL, photodiode, and TIA. 
description: The dataset comprises raw simulation data concerning waveforms and eye diagrams of 50 Gb/s OOK-NRZ signals at various stages, both at the transmitter (Tx) and receiver (Rx) ends.

This version is further enhanced with spectra data captured at the Tx-end. 

These simulations were conducted to assess the transmission performance of the Module-1b SPRINTER prototype, which facilitates a 200 Gb/s aggregated capacity and supports the generation and detection of four 50 GBaud OOK-NRZ signals. The dataset is presented in *.csv format and encompasses results obtained for various operational temperatures of the Tx-side. Additionally, this version contains simulation data for different chirp factors at the Tx end. These evaluations were conducted during transmission through a standard single-mode fiber across for two different fiber lengths (500 m & 1 km).
DOI: 10.5281/zenodo.15299981
title: DS1.1 - Simulation transmission studies of assessing transmission performance of VCSEL-based transmitters across temperature variations and fiber lengths_SPRINTER_v2.0

description: The dataset consists of simulated waveforms and eye diagrams captured at both transmitter (Tx) and receiver (Rx) ends, aiming to assess transmission performance across various operational temperatures of the vertical-cavity surface-emitting laser (VCSEL)-based Tx (25, 55, and 85 °C). 

Specifically, at the Tx-end, the simulation data are enhanced with captured spectra at the VCSEL-based Tx output. For each temperature, the peak-to-peak voltage of the RF electrical input was set at 200 mV, operating at 50 GBaud with an OOK-NRZ modulation format. This peak-to-peak voltage was selected in order to align with the performance of a typical network interface controller. In addition, the chirp factor of the VCSEL-based Tx was set at 10 and 12.

Following this, the transmission performance was examined across fiber lengths of 500 m and 1 km. The exported data focused on capturing the simulation results at three critical stages of the transmission: a) during the generation of the RF 50 GBaud OOK-NRZ signals, b) at the VCSEL output, and c) during the reception of the electrical signal at the Rx-end (transimpedance amplifier (TIA) output). The devices that impose the bandwidth limitations and are investigated in these simulations, were: the laser driver, VCSEL, photodiode, and TIA. 
description: The dataset comprises raw simulation data concerning waveforms and eye diagrams of 50 Gb/s OOK-NRZ signals at various stages, both at the transmitter (Tx) and receiver (Rx) ends.

This version is further enhanced with spectra data captured at the Tx-end. 

These simulations were conducted to assess the transmission performance of the Module-1b SPRINTER prototype, which facilitates a 200 Gb/s aggregated capacity and supports the generation and detection of four 50 GBaud OOK-NRZ signals. The dataset is presented in *.csv format and encompasses results obtained for various operational temperatures of the Tx-side. Additionally, this version contains simulation data for different chirp factors at the Tx end. These evaluations were conducted during transmission through a standard single-mode fiber across for two different fiber lengths (500 m & 1 km).
DOI: 10.6084/m9.figshare.28050104.v1
title: Processed FDI data and import value data of Korea related to Semiconductor and Secondary battery

description: This data is primarily processed from data collected by the Export-Import Bank of Korea and the Korea International Trade Association.
DOI: 10.6084/m9.figshare.13142732.v1
title: Supplementary Material for: Ontogeny and Dynamics of the Gonadal Development, Embryogenesis, and Gestation in Xenotoca eiseni (Cyprinodontiformes, Goodeidae)

description: We characterized the ontogeny and dynamics of gonadal development, embryogenesis, and gestation in captive stocks of the viviparous redtail splitfin,<i> Xenotoca eiseni</i>. Using histology, we showed that gonads were fully differentiated at the time of birth with a male:female sex ratio of 1:1 in the captive stock. External secondary sex features included a modified anal fin and a distinctive orange tail coloration. These features first appeared at 4 weeks after birth and were discriminative for males thereafter. There was no sex-related dichotomy in body size, and <i>X. eiseni</i> reached sexual maturity at approximately 12 weeks of age. We found no evidence for sperm storage in females. Gestation normally took 6 weeks, and there was a positive correlation between female body size and the number of offspring produced, with up to 27 offspring for a single pregnancy. Yolk is the main food source for developing embryos for the period up to 2 weeks, and thereafter, trophotaeniae in embryos act as nutrient exchange surfaces in the ovarian lumen, which subsequently undergo complete regression within 2 weeks of birth. In our final analysis, we discuss the great potential of <i>X. eiseni</i> as a model for studying the effects of chemicals on sexual development.
DOI: 10.6084/m9.figshare.19393910.v1
title: China_Mainland_SCK_Vs30.xlsx

description: Gridded <i>V</i><sub><i>S</i>30</sub> data estimated by SCK model for mainland China.
DOI: 10.15468/dl.3wqj9r
title: Occurrence Download

description: A dataset containing 4300 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Observation, Human Observation, Machine Observation, Living Specimen)"
 ]
 }
 },
 "TaxonKey is Hylaea fasciaria (Linnaeus, 1758)"
 ]
}

 The dataset includes 4300 records from 66 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0009483-250426092105405/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.20522199.v1
title: Salicornia growth trial_ Light and temperature effects

description: Trial to measure the effects of temperature and light on growth of Salicornia ramossisima coupled to a IMRAS system. Salicornias were in floating rafts and periodically supplied water from RAS with Senegalese sole juveniles
DOI: 10.6084/m9.figshare.22306747.v1
title: Molecular dynamics of the ERRγ ligand-binding domain bound with agonist and inverse agonist

description: Moleucular dynamics simulation data of ERRγ bound with agonist and inverse agonist are given. <br> Trajectory files (.xtc) generated using gromacs for apo and ligand bound ERRγ are stored. <br> 100ps coordinates saved after removing PBC for 500ns simulations (.xtc) are given along with .tpr files.