cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.5241259.v1
title: Erratum: Skeletal Muscle Metabolic Gene Expression Is Not Affected by Dichloroacetate-Mediated Modulation of Substrate Utilisation

description: <i>Aim:</i> This study investigated whether changing fuel use, by increasing pyruvate dehydrogenase complex (PDC) flux, independently of plasma substrate availability and insulin signalling, would alter metabolic gene expression. <i>Methods:</i> The PDC activator, dichloroacetate (DCA), was administered as an intravenous infusion in healthy male subjects at a rate of 50 mg kg<sup>–1</sup> min<sup>–1</sup>, for 90 min. Saline was infused as a control (CON) on a separate occasion in a randomised sequence. Muscle biopsies were taken from the vastus lateralis at 0 and 30 min into the infusion and 90 min after infusion. Gene expression was quantified using RT-qPCR, and immunoblotting was used to confirm that there were no changes in insulin signalling via the PI3K/Akt pathway. <i>Results:</i> Blood glucose concentrations fell during both trials but 3 h after the start of the infusion they were lower in DCA (p &lt; 0.05) than CON. Blood lactate concentrations also declined in both trials (p &lt; 0.01), however, this decrease was also more pronounced in DCA than CON (p &lt; 0.001). Carbohydrate oxidation was increased by DCA, 0.037 ± 0.017 g min<sup>–1</sup> (p &lt; 0.05) at 3 h with no change observed in CON. UCP3 and PGC1α mRNA expression were induced in CON (as a response to continued fasting) but this was attenuated by DCA. Akt phosphorylation and the expression of other metabolic genes and transcription factors were unchanged throughout the intervention. <i>Conclusion:</i> It is concluded that PDC flux can be increased independently of plasma substrate availability, without causing downstream alterations to metabolic gene expression in the short term.
DOI: 10.6084/m9.figshare.12354812.v1
title: Data sets and R Code: Evaluating boreal forest restoration strategies after moose (Alces alces) overbrowsing

description: This file contains the R code and data sets used in Noonan et al. Evaluating boreal forest restoration strategies after moose (<i>Alces alces</i>) overbrowsing. <br>
DOI: 10.6084/m9.figshare.29126096.v1
title: Raw data

description: Data for subsequent analysis
DOI: 10.6084/m9.figshare.8120753.v1
title: Table 1 and 2.xlsx

description: This is the excel spreadsheets created as part of my Thesis research. The purpose of this study was to review Sustainability Reports (SRs) issued by The Hartford Financial Services Group (HIG), and determine what concepts of corporate social responsibility (CSR) are reported, to what standard are the reports made, the degree in which corporate activity regarding CSR are reported, and how readily available this information is. Copies of HIG’s SRs were obtained through the Global Reporting Initiative’s (GRI) Sustainability Disclosure Database, and copies of HIG’s Annual 10-K Report to the U.S. Securities and Exchange Commission were obtained through HIG’s Investor Relations website. The disclosures were categorized based on the “three pillars of sustainability” as defined by the Brundtland Commission and Morelli (2011). These disclosures contained classifications under all “three pillars”, with the majority of disclosures falling underneath more than one classification.
DOI: 10.6084/m9.figshare.19222071.v1
title: The ARRIVE Essential 10: author checklist – Ameliorative effect of gel combination of Centella asiatica extract transfersomes and rosemary essential oil nanoemulsion against UVB-induced skin aging in balb/c mice

description: The ARRIVE Essential 10: author checklist generated from “ameliorative effect of gel combination of <i>Centella asiatica</i> extract transfersomes and rosemary essential oil nanoemulsion against UVB-induced skin aging in balb/c mice” submitted to F1000Research
DOI: 10.6084/m9.figshare.2067000.v1
title: Dostępność komunikacyjna polskich miast-gospodarzy turnieju Euro 2012

description: utorzy artykułu mają na celu udowodnienie tezy, iż środki transportu świadczące o dostępności komunikacyjnej polskich miast organizatorów turnieju UEFA EURO 2012 wykazują charakter komplementarny i tylko jako takie są w stanie sprostać postulatom przewozowym stawianym przez wzmożony ruch turystyczny. Od dawna wiadomo, iż sprawna realizacja postulatów przewozowych przyczynia się do zwiększonego ruchu turystycznego oraz jest podstawą do budowania marki turystycznej danego regionu. Przywilej organizacji turnieju piłkarskiego o światowym znaczeniu oprócz wielu korzyści niesie ze sobą jeszcze większą odpowiedzialność władz danego państwa. Autorzy postarają się w poniższym artykule przedstawić osiągnięcia z okresu pięciu lat bezpośrednio przed rozgrywkami, które wpłynęły bezpośrednio na zwiększenie dostępności komunikacyjnej czterech miast-gospodarzy.
DOI: 10.6084/m9.figshare.12449663.v1
title: Air pollutants data in 2020

description: This dataset includes the following data: (1) Daily-average mass concentrations of PM<sub>2.5</sub>, SO<sub>2</sub>, NO<sub>2</sub>, CO and O<sub>3</sub> at the air quality monitoring network in China from January to February in 2020; (2) Comprehensive measurements at Dianshanhu supersite in Shanghai, which provided concentrations of water-soluble ions and carbonaceous aerosols.
DOI: 10.6084/m9.figshare.23884245.v1
title: 出租车OD数据

description: The folder "Taxi OD data" including Taxi OD data for 10 working days. including the boarding and alighting points.
DOI: 10.6084/m9.figshare.27930093.v1
title: CKD_ data

description: Data on the general public to screen the people at risk for CKD and related conditions.
DOI: 10.6084/m9.figshare.28236242.v1
title: High resolution implementation of the Holdridge Life Zone system with transitional zones and altitudinal belts

description: Paper submitted, full text forthcoming.Interactive view available at: https://aenikolopov.projects.earthengine.app/view/hlz<br>Code available: https://github.com/armenenikolopov/HoldridgeLifeZoneMap<br>ABSTRACT:<br>The Holdridge Life Zone (HLZ) system is a widely used framework for ecological classification, yet existing implementations suffer from coarse resolution and inaccurate evapotranspiration estimates. We present the first global 30-arcsecond (~1 km²) global HLZ map, a 3600x improvement over currently available models, addressing critical limitations of previous models. This high-resolution approach is particularly important in topographically complex regions such as the Tropical Andes, where elevation-driven climate changes occur over short distances and are missed in lower-resolution models. Additionally, many transitional life zones predicted by Holdridge are only visible when mapped at fine scales, making this model especially useful for field-based ecological studies and herbarium specimen attribution rather than broad-scale climate applications.<br>A key weakness of the traditional HLZ system is its reliance on a simplified evapotranspiration approximation, which we demonstrate to be several-fold inaccurate outside the tropics and significantly flawed even within them. We provide the first quantitative assessment of where these errors are most severe and introduce a high-resolution alternative using the Penman-Monteith model for improved classification accuracy, particularly in non-tropical regions. These resulting classification differences are discussed. To support broad adoption, we provide open-source code, downloadable datasets, and an interactive web tool for zone determination. This refined HLZ implementation enables more precise ecological fieldwork, floristic studies, biogeographical studies, and climate impact assessments at local scales.<br><br>
DOI: 10.6084/m9.figshare.29108897.v1
title: <b>The Impacts of Socioeconomic, Natural, and Built Environment on Outdoor Exercise in Rapidly Urbanizing Regions</b>

description: This study utilizes survey data from Dongguan, a rapidly urbanizing city in southern China, combined with GIS-based environmental metrics to analyze outdoor exercise patterns across communities with different socioeconomic levels. The dataset incorporates the total exercise duration recorded from 130 neighborhoods/villages, matched with community-level socioeconomic indicators and built/natural environmental characteristics.<br>
DOI: 10.4121/uuid:a98594b5-f612-4ccf-8e0a-952116ec0bc2
title: High-Resolution Magic Angle Spinning Nuclear Magnetic Resonance (HR-MAS-NMR) spectra as quick and direct insight of almonds

description: HR-MAS-NMR spectra of almond samples in D2O By using these data please mention the Natural Product Research publication titled "High-Resolution Magic Angle Spinning Nuclear Magnetic Resonance (HR-MAS-NMR) as quick and direct insight of almonds" by Rotondo et al. 2019
DOI: 10.6084/m9.figshare.20063738.v1
title: Global river sediment dataset 1985~2020

description: Dataset and Code supporting "<b>Changes in global fluvial sediment concentrations and fluxes between 1985 and 2020</b>"
DOI: 10.6084/m9.figshare.27208356.v2
title: language and graph multimodal data for heterogeneous catalyst

description: The DFT-relaxed structure data is originally sourced from the Open Catalyst Project.
DOI: 10.6084/m9.figshare.29092139.v1
title: Source data_Molecular docking

description: Molecular docking results of peptide 1003 with several bacterial proteins
DOI: 10.17632/2f6prz79hy
title: Evaluation of the efficacy and safety of cross-linked hyaluronic acid 30 mg/ml for filling nasolabial folds

description: Introduction: the nasolabial folds (NLF) are a highly mobile facial region that undergoes multifactorial changes during aging. Cientific Hyaluronic Facial Implant 30® is a 30 mg/ml cross-linked hyaluronic acid (HRA) filler developed to optimize the results of this highly dynamic facial area.

Objectives: to evaluate the safety and efficacy of Cientific Hyaluronic Facial Implant 30® (CH30), composed of 30 mg/ml HRA, for the correction of moderate to severe NLF.

Materials and methods: a 12-month, prospective, multicenter clinical study that included 64 male and female patients between 30 and 75 years of age with moderate to severe NLF treated in both NLFs with CH30 to balance the asymmetry until optimal
correction was achieved. Efficacy assessments by evaluators included analysis of NLF severity using the Wrinkle Severity Rating Scale (WSRS) and improvement using the Global Aesthetic Improvement Scale (GAIS). Safety was recorded throughout the study based on checks at each appointment and patient reporting of adverse events.

Results: no adverse events were observed during the 12-month follow-up. In 100% of cases, defect correction, duration, and satisfaction were rated by patients and physicians as “improved” to “very improved,” with a very slow decrease in effect
observed at 12 months.

Conclusions: the use of AHR for the treatment of NLF is one of the most effective and safe options in current aesthetic medicine. Its ability to restore volume, smooth wrinkles, and improve skin quality make it a key tool for facial rejuvenation. The durability of the results, combined with its low complication rate, makes HRA widely recommended for patients seeking a natural and longlasting aesthetic improvement, making it one of the most popular interventions in modern aesthetic medicine.
DOI: 10.6084/m9.figshare.10011788.v2
title: State of Open Data 2019

description: Raw data and questionnaire from the Springer Nature - Digital Science collaboration of an annual survey of research authors on their attitudes and behaviour around research data.
DOI: 10.6084/m9.figshare.28944935.v1
title: Tutorial data for DMC-BrainMap

description: Tutorial dataset for the DMC-BrainMap software.
DOI: 10.17632/bg92x53rk4
title: Naive pluripotent stem cell-based models capture FGF-dependent human hypoblast lineage specification.

description: 10X processed scRNA-seq matrices and H5 files from Cell Ranger pipeline for Dattani et al. (2024), Cell Stem Cell: "Naive pluripotent stem cell-based models capture FGF-dependent human hypoblast lineage specification".

Sequencing was performed on Novaseq 6000, generating paired end reads (28x10x10x90 bases). Sample demultiplexing, alignment, and quantification of barcode counts was performed using Cell Ranger Multi. Cell Ranger .h5 files from individual samples are attached in this dataset together with a .xls containing sample information. 

Scanpy was used to read and analyse raw read counts from the Cell Ranger output. Cells expressing fewer than 15,000 counts, more than 100,0000 counts, or more than 15% mitochondrial reads were filtered out. The resultant count matrix was normalised and log-transformed using reciple_zheng_17. The top 1000 highly variable genes were identified for initial dimensionality reduction with PCA prior to non-linear dimensionality reduction using UMAP. Cells visualised in UMAP plots were coloured according to individual marker gene expression values, and the Leiden algorithm (resolution 0.8) was used to identify cell clusters. Outlier clusters were discarded that likely corresponded to Mouse Embryonic Fibroblasts (DR4 MEFs) or contained dying cells with &gt;~12% mitochondrial reads. 

Attached are two .h5ad.gz files contain normalised counts matrices used for producing UMAPs in Fig1 and Fig5 of doi: https://doi.org/10.1101/2023.11.30.569161. Also included are H5 files from Cell Ranger output. 

For any questions regarding this data, please email: a.dattani@exeter.ac.uk or g.guo@exeter.ac.uk.
DOI: 10.17632/s6zh89fb5c
title: The roadless map of Greece

description: Scientific context
Roadless land conservation is a measurable tool to preserve the nature of high ecological integrity, hamper fragmentation, and address biodiversity decline (Ibisch et al. 2016; Kati et al. 2020). Greece has introduced a roadless legislation to this aim (BCL 2022; Kati et al. 2022) but risks rapid habitat loss from RES deployment (Kati et al. 2021). Biodiversity-inclusive spatial planning is needed, and roadless maps can be valuable tools for this aim under the Global and European Biodiversity Strategy.

Description
The dataset is the roadless map of Greece (5/2022), updating a previous work (Kati et al. 2020). Definitions:  Roadless Core Area (RCA) is any land patch (excluding large waterbodies) that has a size greater than 1 km2 and lies at least 1 km away from the nearest road (accessible by motor vehicles, excluding paths). Roadless Area (RA) is the RCA and its 1 km buffer zone. Roadless Island (RI) and Roadless islet (Ri) are any non-artificial islands that are road-free in all their area, with a size above and below 1 km2, respectively. Roadless Fragmentation Indicator (RFI) is the percentage of RAs plus RIs of the Greek territory. Content: The dataset includes high-confidence data and consists of four sub-databases in kmz format: (a) 389 RCAs (different colors indicate five different size categories: 1-5, 5-10, 10-20,20-50 and >50 km2, (b) 389 RAs (including the RCAs), (c) 62 RI and (d) 3,456 Ris. Nota: The RFI is 6.1%. Most of the roadless sites had a size of over 1,000ha, lying in mountains and islands.

Significance, use, limitations
We recommend using the database to: 
•	Expand the Greek roadless legislation to roadless sites of at least 1,000ha.
•	Include roadless sites in the strictly protected zones of the national network of protected areas (EC 2020).
•	Identify new areas for expanding and connecting the network of protected areas (EC 2020).
•	Define exclusion zones for new infrastructure development across sectors (SEAs) for Renewable Energy Sources, transport, tourism, industry, etc. 
•	Update the SEBI 13 indicator (EEA 2012) and monitor fragmentation in Greece in more natural ecosystems (RFI) 
•	Trigger policies toward landscape conservation and fragmentation minimization (CoE 2000; EC 2020).
•	Identify wilderness areas of Greece and map old-growth forests

Funding
Green Fund of Greece: program “Natural environment and innovative environmental actions 2021”.

References
BCL 2022. https://bc.lab.uoi.gr/en/research/projects/roadless/
CoE 2000. https://www.coe.int/en/web/conventions/full-list/-/conventions/treaty/176 
EC 2020. https://ec.europa.eu/info/files/communication-eu-biodiversity-strategy-2030-bringing-nature-back-our-lives_en 
EEA 2012. https://www.eea.europa.eu/publications/streamlining-european-biodiversity-indicators-2020 
Ibisch et al. 2016. http://doi.org/10.1126/science.aaf7166 
Kati et al. 2020. https://doi.org/10.3390/d12040124 
Kati et al. 2022. https://doi.org/10.1126/science.abo2014
DOI: 10.6084/m9.figshare.19850641.v1
title: Parameters and Modeling Instructions.rarResearch on equivalent model of pedestrian bridge deck based on stainless steel core plate

description: <strong>Research on equivalent model of pedestrian bridge deck based on stainless steel core plate</strong>
DOI: 10.6084/m9.figshare.27138573.v1
title: 20241001_starrydata2

description: All data on Starrydata2, a database of experimental properties in the field of inorganic materials
DOI: 10.6084/m9.figshare.28143381.v1
title: Semiparametric Regression Analysis of Interval-Censored Multi-State Data with An Absorbing State

description: In studies of chronic diseases, the health status of a subject can often be characterized by a finite number of transient disease states and an absorbing state, such as death. The times of transitions among the transient states are ascertained through periodic examinations and thus interval-censored. The time of reaching the absorbing state is known or right-censored, with the transient state at the previous instant being unobserved. In this article, we provide a general framework for analyzing such multi-state data. We formulate the effects of potentially time-dependent covariates on the multi-state disease process through semiparametric proportional intensity models with random effects. We combine nonparametric maximum likelihood estimation with sieve estimation and develop a stable expectation-maximization algorithm. We establish the asymptotic properties of the proposed estimators through novel use of modern empirical process theory, sieve estimation theory, and semiparametric efficiency theory. In addition, we dynamically predict future states and survival time using the evolving disease history. Finally, we assess the performance of the proposed methods through extensive simulation studies and provide an illustration with a cardiac allograft vasculopathy study. Supplementary materials for this article are available online, including a standardized description of the materials available for reproducing the work.
DOI: 10.6084/m9.figshare.899204.v1
title: Index Reads - File B - Second Sequencing Run

description: Raw sequence files were split up due to upload limits. This file is in two parts (a and b). Concatenate these files before analysis.
DOI: 10.6084/m9.figshare.7038590.v1
title: Comparação entre avaliação cinemática 2D e 3D da corrida

description: Arquivos do trabalho de iniciação científica que visou fazer uma revisão da literatura sobre a confibilidade e validade da cinemática 2D da corrida e um estudo de caso de comparando a cinemática 2D com a 3D de um sujeito saudável durante a corrida em esteira a 3,5 m/h.
DOI: 10.6084/m9.figshare.7670519.v1
title: Dataset MPVh y2019m02

description: Background: Human Metapneumovirus (hMPV) is a negative single-stranded RNA virus. Infection by hMPV mainly affects the pediatric population and can cause upper or lower respiratory tract pathologies which can develop life threating complications. This study was carried out between 2009 and 2010 in a high complexity national hospital in Lima, Peru. The time frame corresponds to the pandemic of influenza A H1N1. Methods: RT-PCR was utilized to attain the amplification and identification of the virus.Results: A total of 539 samples were analized from patients with a clinical context suggestive of an acute respiratory tract infection. Of these samples 73 (13.54%) were positive for hMPV. Out of the positive cases, 63% were under 1 year old, and increased to nearly 80% when considering children younger than 2 years old. Cough was the most frequent symptom presented by our population with a number of 62 cases (84.93%). Viral seasonality was also established, noting its predominance during the months of summer in the southern hemisphere.Conclusions: The infection by hMPV has an important prevalence in Peru. It mainly affects children under 1 year old and can cause both upper and lower respiratory tract infections that can develop into potential life threating complications.<br>
DOI: 10.6084/m9.figshare.8293325.v1
title: PretoriaData.m from Nectar, humidity, honey bees (<i>Apis mellifera</i>) and varroa in summer: a theoretical thermofluid analysis of the fate of water vapour from honey ripening and its implications on the control of <i>Varroa destructor</i>

description: This theoretical thermofluid analysis investigates the relationships between honey production rate, nectar concentration and the parameters of entrance size, nest thermal conductance, brood nest humidity and the temperatures needed for nectar to honey conversion. It quantifies and shows that nest humidity is positively related to the amount, and water content of the nectar being desiccated into honey and negatively with respect to nest thermal conductance and entrance size. It is highly likely that honeybees, in temperate climates and in their natural home, with much smaller thermal conductance and entrance, can achieve higher humidities more easily and more frequently than in man-made hives. As a consequence, it is possible that <i>Varroa destructor</i>, a parasite implicated in the spread of pathogenic viruses and colony collapse, which loses fecundity at absolute humidities of 4.3 kPa (approx. 30 gm<sup>−3</sup>) and above, is impacted by the more frequent occurrence of higher humidities in these low conductance, small entrance nests. This study provides the theoretical basis for new avenues of research into the control of varroa, via the modification of beekeeping practices to help maintain higher hive humidities.
DOI: 10.17632/nhx267cffj
title: Database PYD Arequipa 2024

description: PYD database Arequipa, Peru, 2024