cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17632/fj6nwvbt48.1
title: Large-scale Ridesharing DARP Instances Based on Real Travel Demand

description: This dataset presents a set of large-scale Dial-a-Ride Problem (DARP) instances. The instances were created as a standardized set of ridesharing DARP problems for the purpose of benchmarking and comparing different solution methods. The instances are based on real demand and realistic travel time data from 3 different US cities: Chicago, New York City, and Washington, DC. The instances consist of real travel requests from the selected period, positions of vehicles with their capacities, and realistic shortest travel times between all pairs of locations in each city. The instances and results of two solution methods, the Insertion Heuristic and the optimal Vehicle-group Assignment method, can be found in the dataset. 📄 Paper: arXiv:2305.18859 📁 Data: DOI:10.5281/zenodo.7986103 👩‍💻 Code: https://github.com/aicenter/Ridesharing_DARP_instances The dataset was presented at the IEEE International Conference on Intelligent Transportation Systems (ITSC 2023) in Bilbao, Bizkaia, Spain, 24-28 September 2023 (Session CON03)
DOI: 10.5281/zenodo.8416909
title: Cobalt datapackage for unfold

description: Datapackage for unfold.
DOI: 10.5281/zenodo.10259754
title: Cobalt datapackage for unfold

description: Datapackage for unfold.
DOI: 10.5281/zenodo.8416908
title: Cobalt datapackage for unfold

description: Datapackage for unfold.
DOI: 10.5281/zenodo.8418163
title: Cobalt datapackage for unfold

description: Datapackage for unfold.
DOI: 10.17632/thfkcryrj9.1
title: Ninety-Four Most Frequent Characters and Sixteen Lexical Features of Three Ancient Chinese Vernacular Novels

description: This dataset provides a normalized frequency of ninety-four Most Frequent Characters (MFCs) and normalized values of sixteen lexical features of each chapter of three ancient Chinese vernacular novels, Marriage Bonds to Awaken the World (Xing Shi Yin Yuan Zhuan 醒世姻緣傳; MBAW), Pu Songling’s Popular Songs from Leisure Studio (Liao Zhai Li Qu Ji 聊齋俚曲集; PSLS), and Ding Yaokang’s Sequel to the Plum in Golden Vase (Xu Jin Ping Mei 續金瓶梅; SPGV). MBAW is an important work in the developing process of Chinese long vernacular novels. However, a significant question of MBAW, the authorship of this novel, remains shrouded in mystery. There are two dominant conjectures about the author of MBAW, one is Pu Songling 蒲松齡 (1640-1715) and the other is Ding Yaokang 丁耀亢 (1599-1669). The data can be used to evaluate if the authorship of MBAW can be attributed to either Pu Songling or Ding Yaokang through a comparative examination of the linguistic stylings of MBAW and two other novels from the same genre, PSLS and SPGV, which have been confirmed as the works of Pu Songling and Ding Yaokang, respectively. The 94 MFCs of the two novels are as follows: 了, 的, 不, 一, 是, 人, 他, 說, 來, 子, 你, 我, 個, 這, 那, 有, 道, 著, 也, 去, 家, 上, 裡, 大, 在, 就, 到, 得, 又, 兩, 日, 麼, 下, 只, 好, 見, 要, 頭, 還, 叫, 出, 兒, 沒, 把, 看, 老, 二, 小, 姐, 十, 娘, 生, 三, 門, 都, 回, 如, 打, 知, 心, 做, 才, 相, 起, 自, 過, 可, 合, 天, 時, 事, 與, 官, 甚, 銀, 公, 中, 夫, 吃, 前, 無, 後, 將, 怎, 們, 年, 外, 些, 問, 走, 聽, 待, 多, and 進. Definitions of the 16 lexical features are provided in the second worksheet of the Excel file named “Lexical features”.
DOI: 10.17632/w5zy4vct6r.1
title: Clinical-histopathological features and cancer gene analysis of cutaneous epithelioid angiosarcoma: a report of four cases

description: We have summarized the clinical information for the four epithelioid angiosarcoma.
DOI: 10.17632/5kn9m9cwg5.1
title: Supplementary data of "Blood Lipid Metabolic Profiles and Causal Links to Site-Specific Cancer Risks"

description: Observational and Mendelian randomization (MR) studies have established links between dyslipidemia and select cancer susceptibilities. However, there is a lack of comprehensive exploration of causal relationships spanning diverse cancer types. Here, we conducted a two-sample MR analysis to elucidate the causative connections between 9 blood lipid metabolic profiles (namely, adiponectin, leptin, lipoprotein A, apolipoprotein A1, apolipoprotein B, cholesterol, triglycerides, LDL-cholesterol, and HDL-cholesterol) and 21 site-specific cancer risks. Our findings reveal genetically predicted adiponectin levels to be associated with a reduced ovarian cancer risk, while genetically determined leptin increases bladder cancer risk but decreases prostate cancer risk. Lipoprotein A elevates risk of prostate cancer while diminishing risk of endometrial cancer, while apolipoprotein A1 heightens risks of breast and cervical cancers. Furthermore, elevated levels of cholesterol are positively correlated with kidney cancer, and triglycerides demonstrate a positive association with non-melanoma skin cancer but a negative association with breast cancer. Protective effects of genetically predicted LDL-cholesterol on endometrial cancer and adverse effects of HDL-cholesterol on breast cancer are also observed. Our study conclusively establishes that blood lipid metabolic profiles exert causal effects on cancer susceptibility, providing more robust evidence for cancer prevention and prompting contemplation regarding the future health of the human populace.
DOI: 10.5281/zenodo.10214922
title: INTERACT arctic research stations: Historic weather data fetched and plotted from Copernicus Climate Data Store

description: Plots with historic weather data for arctic research stations covered by International Network for Terrestrial Research and Monitoring in the Arctic (INTERACT). Comparison with WMO climate normal periods 1961-1990 and 1991-2020, averages and stations deviations from the normal periods are calculated and plotted.
The data source for historic data of temperature and precipitation is: 
Hersbach, H., Bell, B., Berrisford, P., Biavati, G., Horányi, A., Muñoz Sabater, J., Nicolas, J., Peubey, C., Radu, R., Rozum, I., Schepers, D., Simmons, A., Soci, C., Dee, D., Thépaut, J-N. (2023): ERA5 monthly averaged data on single levels from 1940 to present. Copernicus Climate Change Service (C3S) Climate Data Store (CDS), DOI: 10.24381/cds.f17050d7  
See the linked github repository https://zenodo.org/doi/10.5281/zenodo.10214962 for how data was fetched from Copernicus Climate Data Store, prepared and plotted. The github repository also contains CSVs with source data for the plots.
DOI: 10.5281/zenodo.10214923
title: INTERACT arctic research stations: Historic weather data fetched and plotted from Copernicus Climate Data Store

description: Plots with historic weather data for arctic research stations covered by International Network for Terrestrial Research and Monitoring in the Arctic (INTERACT). Comparison with WMO climate normal periods 1961-1990 and 1991-2020, averages and stations deviations from the normal periods are calculated and plotted.
The data source for historic data of temperature and precipitation is: 
Hersbach, H., Bell, B., Berrisford, P., Biavati, G., Horányi, A., Muñoz Sabater, J., Nicolas, J., Peubey, C., Radu, R., Rozum, I., Schepers, D., Simmons, A., Soci, C., Dee, D., Thépaut, J-N. (2023): ERA5 monthly averaged data on single levels from 1940 to present. Copernicus Climate Change Service (C3S) Climate Data Store (CDS), DOI: 10.24381/cds.f17050d7  
See the linked github repository https://zenodo.org/doi/10.5281/zenodo.10214962 for how data was fetched from Copernicus Climate Data Store, prepared and plotted. The github repository also contains CSVs with source data for the plots.
DOI: 10.6084/m9.figshare.24649515
title: Supplementary Material for: Evaluation of bone mineral density in lung transplant recipients by chest computed tomography

description: Introduction: Lung transplantation (LT) recipients are at risk of bone mineral density (BMD) loss. Pre- and post-LT BMD loss has been reported in some cross-sectional studies; however, there are limited studies regarding the serial BMD change in LT recipients. The aim of this study was to investigate the serial BMD changes and the clinical characteristics associated with BMD decline. Methods: This was a single-center, retrospective observational study. BMD was serially measured in thoracic vertebral bodies (Th4, 7, 10) using computed tomography (CT) before and 3 and 12 months after LT. The frequency of osteoporosis and factors associated with pre-LT osteoporosis and post-LT BMD loss were evaluated. The frequency of post-LT compression fracture and its associated factors were also analyzed. Results: This study included 128 adult LT recipients. LT recipients had decreased BMD (151.8 ± 42.2 mg/mL) before LT compared with age-, sex-, and smoking index-matched controls (176.2 ± 35.7 mg/mL). The diagnosis of COPD was associated with pre-LT osteoporosis. LT recipients experience further BMD decline after transplantation, and the percentage of recipients classified as exhibiting osteoporosis increased from 20% at baseline to 43% at 12 months. Recipients who had been taking no or small doses of glucocorticoids before LT had rapid BMD loss after LT. Early bisphosphonate use (within 3 months) after LT attenuated BMD loss and decreased new-onset compression fracture. Conclusion: LT recipients are at high risk for BMD loss and compression fracture after LT. Early bisphosphonate use may decrease BMD loss and compression fracture.
DOI: 10.6084/m9.figshare.24649515.v1
title: Supplementary Material for: Evaluation of bone mineral density in lung transplant recipients by chest computed tomography

description: Introduction: Lung transplantation (LT) recipients are at risk of bone mineral density (BMD) loss. Pre- and post-LT BMD loss has been reported in some cross-sectional studies; however, there are limited studies regarding the serial BMD change in LT recipients. The aim of this study was to investigate the serial BMD changes and the clinical characteristics associated with BMD decline. Methods: This was a single-center, retrospective observational study. BMD was serially measured in thoracic vertebral bodies (Th4, 7, 10) using computed tomography (CT) before and 3 and 12 months after LT. The frequency of osteoporosis and factors associated with pre-LT osteoporosis and post-LT BMD loss were evaluated. The frequency of post-LT compression fracture and its associated factors were also analyzed. Results: This study included 128 adult LT recipients. LT recipients had decreased BMD (151.8 ± 42.2 mg/mL) before LT compared with age-, sex-, and smoking index-matched controls (176.2 ± 35.7 mg/mL). The diagnosis of COPD was associated with pre-LT osteoporosis. LT recipients experience further BMD decline after transplantation, and the percentage of recipients classified as exhibiting osteoporosis increased from 20% at baseline to 43% at 12 months. Recipients who had been taking no or small doses of glucocorticoids before LT had rapid BMD loss after LT. Early bisphosphonate use (within 3 months) after LT attenuated BMD loss and decreased new-onset compression fracture. Conclusion: LT recipients are at high risk for BMD loss and compression fracture after LT. Early bisphosphonate use may decrease BMD loss and compression fracture.
DOI: 10.6084/m9.figshare.24540946
title: Supplementary Material for: miR-874-3p is identified as a biomarker for acute kidney injury and mediates disease development via targeting MSRB3

description: Introduction: Acute kidney injury (AKI) is a common clinical disease, especially in the intensive care unit. Identification of reliable biomarker is of great clinical significance and benefit the therapy and prevention of AKI. The clinical significance and function of miR-874-3p in AKI development were evaluated in this study aiming to explore a novel biomarker for AKI. Methods: There were 83 AKI patients and 56 healthy individuals included and the serum samples were collected. The AKI animal models were established via ischemic/reperfusion and LPS on C57BL/6 mice. The expression of miR-874-3p was evaluated using PCR, while the potential downstream targets were also validated in AKI mice. Results: miR-874-3p was downregulated in both AKI patients and established AKI mice models. The downregulation of miR-874-3p could discriminate against AKI patients and predict poor prognosis of patients. miR-874-3p was negatively correlated with the levels of Scr, BUN, CRP, NEU, and PCT and positively correlated with the eGFR of AKI patients. In I/R- and LPS-induced AKI mice, overexpressing miR-874-3p could alleviate renal dysfunction, oxidative stress, and inflammation induced by AKI. Additionally, miR-874-3p could negatively regulate the expression of MSRB3, which was speculated as the potential mechanism underlying the function of miR-874-3p in AKI. Conclusion: miR-874-3p served as a diagnostic and prognostic biomarker of AKI and mediate the severity and development of AKI via targeting MSRB3.
DOI: 10.6084/m9.figshare.24540946.v1
title: Supplementary Material for: miR-874-3p is identified as a biomarker for acute kidney injury and mediates disease development via targeting MSRB3

description: Introduction: Acute kidney injury (AKI) is a common clinical disease, especially in the intensive care unit. Identification of reliable biomarker is of great clinical significance and benefit the therapy and prevention of AKI. The clinical significance and function of miR-874-3p in AKI development were evaluated in this study aiming to explore a novel biomarker for AKI. Methods: There were 83 AKI patients and 56 healthy individuals included and the serum samples were collected. The AKI animal models were established via ischemic/reperfusion and LPS on C57BL/6 mice. The expression of miR-874-3p was evaluated using PCR, while the potential downstream targets were also validated in AKI mice. Results: miR-874-3p was downregulated in both AKI patients and established AKI mice models. The downregulation of miR-874-3p could discriminate against AKI patients and predict poor prognosis of patients. miR-874-3p was negatively correlated with the levels of Scr, BUN, CRP, NEU, and PCT and positively correlated with the eGFR of AKI patients. In I/R- and LPS-induced AKI mice, overexpressing miR-874-3p could alleviate renal dysfunction, oxidative stress, and inflammation induced by AKI. Additionally, miR-874-3p could negatively regulate the expression of MSRB3, which was speculated as the potential mechanism underlying the function of miR-874-3p in AKI. Conclusion: miR-874-3p served as a diagnostic and prognostic biomarker of AKI and mediate the severity and development of AKI via targeting MSRB3.
DOI: 10.6084/m9.figshare.24551227
title: Supplementary Material for: Comparative cytogenetic analysis of diploid and triploid pacific abalone, Haliotis discus hannai

description: Cytogenetic analysis of triploid Haliotis discus hannai larvae (produced by chemical treatment) and its diploids were performed. The results showed that triploid H. discus hannai had a chromosome number of 3n = 54, consisting of 30 metacentric (m) and 24 submetacentric (sm) chromosomes, while the diploids had a chromosome number of 2n = 36, consisting of 20 metacentric (m) and 16 submetacentric (sm) chromosomes. Notably, both triploids and diploids displayed variation in the number of NORs and/or their diameter. The average number of NORs was significantly higher in triploids than in diploids (P &lt; 0.05), while there was no significant difference in the average diameter of NORs between the two groups (P &gt; 0.05). Additionally, 5S rDNA localization to 3 submetacentric chromosomes was observed in triploids, compared to 2 submetacentric chromosomes in diploids. The number of 18S rDNA sites displayed positional conservancy and quantitative variability in both diploids and triploids. Specifically, 18S rDNA was found at the end of the chromosome in both groups, with triploids exhibiting a significantly higher number of loci than diploids (P &lt; 0.01). This study provides valuable insights into the cytogenetic characteristics of triploid H. discus hannai, which could facilitate further research on the stability of the chromosome set in this species.
DOI: 10.6084/m9.figshare.24551227.v1
title: Supplementary Material for: Comparative cytogenetic analysis of diploid and triploid pacific abalone, Haliotis discus hannai

description: Cytogenetic analysis of triploid Haliotis discus hannai larvae (produced by chemical treatment) and its diploids were performed. The results showed that triploid H. discus hannai had a chromosome number of 3n = 54, consisting of 30 metacentric (m) and 24 submetacentric (sm) chromosomes, while the diploids had a chromosome number of 2n = 36, consisting of 20 metacentric (m) and 16 submetacentric (sm) chromosomes. Notably, both triploids and diploids displayed variation in the number of NORs and/or their diameter. The average number of NORs was significantly higher in triploids than in diploids (P &lt; 0.05), while there was no significant difference in the average diameter of NORs between the two groups (P &gt; 0.05). Additionally, 5S rDNA localization to 3 submetacentric chromosomes was observed in triploids, compared to 2 submetacentric chromosomes in diploids. The number of 18S rDNA sites displayed positional conservancy and quantitative variability in both diploids and triploids. Specifically, 18S rDNA was found at the end of the chromosome in both groups, with triploids exhibiting a significantly higher number of loci than diploids (P &lt; 0.01). This study provides valuable insights into the cytogenetic characteristics of triploid H. discus hannai, which could facilitate further research on the stability of the chromosome set in this species.
DOI: 10.57745/gml9xv
title: rmqs1_16S_microbial_habitat.tab

description: habitat code for 1789 samples from RMQS
DOI: 10.57745/mpmw8o
title: rmqs1_16S_microbial_habitat.metadata.tab

description: name and pH complex of each habitat
DOI: 10.5519/qd.kid6s7cj
title: Query on the Natural History Museum Data Portal (data.nhm.ac.uk) (642877 records)
DOI: 10.6084/m9.figshare.24581562
title: Supplementary Material for: The association between dapagliflozin use and the risk of post contrast acute kidney injury in patients with type 2 diabetes and chronic kidney disease: a propensity-matched analysis

description: Introduction This study aimed to investigate the effect of dapagliflozin in preventing post contrast acute kidney injury (PC-AKI) in patients with type 2 diabetes (T2DM) and chronic kidney disease (CKD) who underwent an elective coronary procedure. Methods Data of patients with T2DM and CKD undergoing an elective coronary procedure at Civil Aviation General Hospital from October 2020 to April 2023, were collected from the electronic medical records. Based on dapagliflozin usage, patients were classified as dapagliflozin users and non-users. 1:1 nearest-neighbor propensity matching was performed to compare dapagliflozin users with non-users. The primary endpoint was the first PC-AKI observed. Univariate and multivariate COX regression models were used to determine the independent risk/preventive factors for PC-AKI. Thereafter, subgroup analyses were performed to evaluate the interaction between subgroup and dapagliflozin usage. Changes in the serum creatinine (SCr) and cystatin C (CysC) levels were monitored at 24h, 48h and 72h after the procedure. Results 256 pairs (256 dapagliflozin users in the dapagliflozin group and 256 dapagliflozin non-users in the control group) were identified in the cohort. The incidence of PC-AKI in dapagliflozin group (10.9%) was lower than that in control group (22.3%). COX regression analyses showed that dapagliflozin use was associated with a lower risk of PC-AKI (HR 0.81, 95% CI: 0.69-0.95, P=0.01) after adjustment for covariates. In the subgroup analyses, similar HRs of the dapagliflozin usage on the PC-AKI outcome were observed in patients across different patients’ characteristics which revealed its consistent benefit of preventing PC-AKI. The eGFR levels at post-48h and 72h were significant higher in the dapagliflozin group than those in the control group, while levels of SCr (post-48h and 72h) and CysC (post-24h and 48h) in the dapagliflozin group were lower compared with the control group. Conclusion Our findings suggest dapagliflozin effectively decrease PC-AKI risk and exert reno-protective effects in patients with T2DM and CKD undergoing an elective coronary procedure.
DOI: 10.6084/m9.figshare.24581562.v1
title: Supplementary Material for: The association between dapagliflozin use and the risk of post contrast acute kidney injury in patients with type 2 diabetes and chronic kidney disease: a propensity-matched analysis

description: Introduction This study aimed to investigate the effect of dapagliflozin in preventing post contrast acute kidney injury (PC-AKI) in patients with type 2 diabetes (T2DM) and chronic kidney disease (CKD) who underwent an elective coronary procedure. Methods Data of patients with T2DM and CKD undergoing an elective coronary procedure at Civil Aviation General Hospital from October 2020 to April 2023, were collected from the electronic medical records. Based on dapagliflozin usage, patients were classified as dapagliflozin users and non-users. 1:1 nearest-neighbor propensity matching was performed to compare dapagliflozin users with non-users. The primary endpoint was the first PC-AKI observed. Univariate and multivariate COX regression models were used to determine the independent risk/preventive factors for PC-AKI. Thereafter, subgroup analyses were performed to evaluate the interaction between subgroup and dapagliflozin usage. Changes in the serum creatinine (SCr) and cystatin C (CysC) levels were monitored at 24h, 48h and 72h after the procedure. Results 256 pairs (256 dapagliflozin users in the dapagliflozin group and 256 dapagliflozin non-users in the control group) were identified in the cohort. The incidence of PC-AKI in dapagliflozin group (10.9%) was lower than that in control group (22.3%). COX regression analyses showed that dapagliflozin use was associated with a lower risk of PC-AKI (HR 0.81, 95% CI: 0.69-0.95, P=0.01) after adjustment for covariates. In the subgroup analyses, similar HRs of the dapagliflozin usage on the PC-AKI outcome were observed in patients across different patients’ characteristics which revealed its consistent benefit of preventing PC-AKI. The eGFR levels at post-48h and 72h were significant higher in the dapagliflozin group than those in the control group, while levels of SCr (post-48h and 72h) and CysC (post-24h and 48h) in the dapagliflozin group were lower compared with the control group. Conclusion Our findings suggest dapagliflozin effectively decrease PC-AKI risk and exert reno-protective effects in patients with T2DM and CKD undergoing an elective coronary procedure.