cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.4811074
title: Supplementary Material for: Volume and Characteristics of Intracerebral Hemorrhage with Direct Oral Anticoagulants in Comparison with Warfarin

description: <i>Background:</i> Patients undergoing anticoagulation therapy often experience intracerebral hemorrhages (ICHs), and warfarin in particular is known to increase hematoma expansion in ICHs, which results in a poor outcome. Recent studies reported that, in comparison with warfarin, direct oral anticoagulants (DOACs) cause fewer ICHs with better functional outcome. However, since it is still unknown whether DOACs are associated with a smaller hematoma volume of ICHs, we aimed to compare the volume, hematoma expansion, and outcomes associated with ICHs treated with DOACs and warfarin. <i>Methods:</i> We performed a prospective multicenter cross-sectional study. The subjects included patients with acute ICHs who received either DOACs or warfarin. We evaluated the clinical characteristics, and measured initial and follow-up ICH volumes. The volume of ICHs and hematoma expansion were compared between the DOAC and warfarin groups. Mortality and modified Rankin score at discharge were evaluated as outcomes. <i>Results:</i> There were 18 patients in the DOAC group and 71 in the warfarin group. The baseline characteristics were similar between the 2 groups. Initial median hematoma volume of ICHs in the DOAC group was significantly lower than that in the warfarin group (6.2 vs. 24.2 mL, respectively; <i>p</i> = 0.04). In cases involving follow-up computed tomography scanning, the median hematoma volume of ICHs at follow-up was lower in the DOAC group than in the warfarin group (initial: DOACs 4.4 vs. warfarin 13.5 mL; follow-up: 5.0 vs. 18.4 mL, respectively; <i>p</i> = 0.05). Further, the hematoma in ICHs associated with DOACs did not expand. Although the mortality of ICHs associated with DOACs (11%) was lower than that associated with warfarin (24%), this difference was not statistically significant. The univariate analysis showed that the anticoagulant type (DOACs vs. warfarin) and sex (male vs. female) were associated with ICH volume. The multivariable linear regression showed that the use of DOACs (compared to warfarin; β: –0.23, <i>p</i> = 0.03) and female sex (compared to male; β: –0.25, <i>p</i> = 0.02) were associated with a small hematoma volume. <i>Conclusions:</i> Based on the results of the present study, in terms of the risks associated with ICHs, the use of DOACs appears to be safer than warfarin for anticoagulation therapy. Further studies are required to validate these findings.
DOI: 10.6084/m9.figshare.4811074.v1
title: Supplementary Material for: Volume and Characteristics of Intracerebral Hemorrhage with Direct Oral Anticoagulants in Comparison with Warfarin

description: <i>Background:</i> Patients undergoing anticoagulation therapy often experience intracerebral hemorrhages (ICHs), and warfarin in particular is known to increase hematoma expansion in ICHs, which results in a poor outcome. Recent studies reported that, in comparison with warfarin, direct oral anticoagulants (DOACs) cause fewer ICHs with better functional outcome. However, since it is still unknown whether DOACs are associated with a smaller hematoma volume of ICHs, we aimed to compare the volume, hematoma expansion, and outcomes associated with ICHs treated with DOACs and warfarin. <i>Methods:</i> We performed a prospective multicenter cross-sectional study. The subjects included patients with acute ICHs who received either DOACs or warfarin. We evaluated the clinical characteristics, and measured initial and follow-up ICH volumes. The volume of ICHs and hematoma expansion were compared between the DOAC and warfarin groups. Mortality and modified Rankin score at discharge were evaluated as outcomes. <i>Results:</i> There were 18 patients in the DOAC group and 71 in the warfarin group. The baseline characteristics were similar between the 2 groups. Initial median hematoma volume of ICHs in the DOAC group was significantly lower than that in the warfarin group (6.2 vs. 24.2 mL, respectively; <i>p</i> = 0.04). In cases involving follow-up computed tomography scanning, the median hematoma volume of ICHs at follow-up was lower in the DOAC group than in the warfarin group (initial: DOACs 4.4 vs. warfarin 13.5 mL; follow-up: 5.0 vs. 18.4 mL, respectively; <i>p</i> = 0.05). Further, the hematoma in ICHs associated with DOACs did not expand. Although the mortality of ICHs associated with DOACs (11%) was lower than that associated with warfarin (24%), this difference was not statistically significant. The univariate analysis showed that the anticoagulant type (DOACs vs. warfarin) and sex (male vs. female) were associated with ICH volume. The multivariable linear regression showed that the use of DOACs (compared to warfarin; β: –0.23, <i>p</i> = 0.03) and female sex (compared to male; β: –0.25, <i>p</i> = 0.02) were associated with a small hematoma volume. <i>Conclusions:</i> Based on the results of the present study, in terms of the risks associated with ICHs, the use of DOACs appears to be safer than warfarin for anticoagulation therapy. Further studies are required to validate these findings.
DOI: 10.6084/m9.figshare.4811026
title: Matlab script to run one realisation of the three plates example (figure 7 and 8) from Coupling strength assumption in statistical energy analysis

description: Matlab script to run one realisation of the three plates example (figure 7 and 8)
DOI: 10.6084/m9.figshare.4811035
title: MOUtbhR RNA-seq quantitative analysis

description: RNA-seq pipeline analysis of mouse single end libraries.
DOI: 10.6084/m9.figshare.4811014
title: RIECCU_ECG_DATA from Multiscale ordinal network analysis of human cardiac dynamics

description: ECG records analysed in Section 5a of the manuscript (anonymised)
DOI: 10.6084/m9.figshare.4811017
title: Matlab script to plot figure 3 from Coupling strength assumption in statistical energy analysis

description: Matlab script to plot figure 3
DOI: 10.6084/m9.figshare.4811014.v1
title: RIECCU_ECG_DATA from Multiscale ordinal network analysis of human cardiac dynamics

description: ECG records analysed in Section 5a of the manuscript (anonymised)
DOI: 10.6084/m9.figshare.4811002
title: Appendix S2 from Chance long-distance or human-mediated dispersal? How <i>Acacia s.l. farnesiana</i> attained its pan-tropical distribution

description: Microsatellite PCR product lengths for each locus for each Acacia farnesiana individual used in this study.
DOI: 10.6084/m9.figshare.4811002.v1
title: Appendix S2 from Chance long-distance or human-mediated dispersal? How <i>Acacia s.l. farnesiana</i> attained its pan-tropical distribution

description: Microsatellite PCR product lengths for each locus for each Acacia farnesiana individual used in this study.
DOI: 10.6084/m9.figshare.4810993
title: Adolescent SRQ dataset from Social Reward Questionnaire–Adolescent Version and its association with callous–unemotional traits

description: Complete dataset
DOI: 10.6084/m9.figshare.4810996
title: Matlab script to plot figure 2 from Coupling strength assumption in statistical energy analysis

description: Matlab script to plot figure 2
DOI: 10.6084/m9.figshare.4810972
title: HGT in Spirochaetes

description: HGT in human gut microbes: Horizontally transferred genes received by Spirochaetes species.
DOI: 10.6084/m9.figshare.4810975
title: Verrucomicrobia

description: HGT in human gut microbes: Horizontally transferred genes received by Verrucomicrobia species.
DOI: 10.6084/m9.figshare.4810966
title: HGT Proteobacteria-part I

description: HGT in human gut microbes: Horizontally transferred genes received by Proteobacteria species
DOI: 10.6084/m9.figshare.4810975.v1
title: Verrucomicrobia

description: HGT in human gut microbes: Horizontally transferred genes received by Verrucomicrobia species.
DOI: 10.6084/m9.figshare.4810966.v1
title: HGT Proteobacteria-part I

description: HGT in human gut microbes: Horizontally transferred genes received by Proteobacteria species
DOI: 10.6084/m9.figshare.4810972.v1
title: HGT in Spirochaetes

description: HGT in human gut microbes: Horizontally transferred genes received by Spirochaetes species.
DOI: 10.6084/m9.figshare.4810963
title: HGT in Firmicutes

description: HGT in human gut microbes: Horizontally transferred genes received by Firmicutes.
DOI: 10.6084/m9.figshare.4810993.v1
title: Adolescent SRQ dataset from Social reward questionnaire: adolescent version and its association with callous–unemotional traits

description: Complete dataset
DOI: 10.6084/m9.figshare.4810960
title: HGT in Bacteroidetes

description: HGT in human gut microbes: Horizontally transferred genes received by Bacteroidetes species.
DOI: 10.6084/m9.figshare.4810963.v1
title: HGT in Firmicutes

description: HGT in human gut microbes: Horizontally transferred genes received by Firmicutes.
DOI: 10.6084/m9.figshare.4810927
title: One-dimensional steady-state thermal model for rotary kilns used in the manufacture of cement

description: Rotary kilns are used extensively in the cement industry to convert raw meal into cement clinker. In order to optimise the operation of cement kilns, computationally efficient thermal models are required. In this work, the development of a one-dimensional thermal model for kilns is explored. To simplify the model, the kiln is assumed to be well mixed in the transverse direction. A simultaneous mass and energy balance is solved based on a steady-state approximation. Existing semi-empirical models for heat transfer in the kiln are implemented and critically evaluated. The resulting one-dimensional model is capable of predicting axial temperature profiles in the rotary kiln which agree well with the available experimental data found in the literature. The model presented here extends from previous published models by considering a full enthalpy balance for the gas in the kiln. This allows the model to be used in a fully predictive manner, taking into account the temperature-dependent thermodynamic, transport, and radiative properties of the gas phase.
DOI: 10.6084/m9.figshare.4810957
title: HGT in Archaea-part I

description: HGT in human gut microbes: Horizontally transferred genes received by Archaea species.
DOI: 10.6084/m9.figshare.4810915
title: Nuclear PAR quantification (ENZO)

description: Some original slices and correspondent quantification.GFP means PAR.
DOI: 10.6084/m9.figshare.4810915.v1
title: Nuclear PAR quantification (ENZO)

description: Some original slices and correspondent quantification.GFP means PAR.
DOI: 10.6084/m9.figshare.4810957.v1
title: HGT in Archaea-part I

description: HGT in human gut microbes: Horizontally transferred genes received by Archaea species.
DOI: 10.6084/m9.figshare.4810960.v2
title: HGT in Bacteroidetes

description: HGT in human gut microbes: Horizontally transferred genes received by Bacteroidetes species.
DOI: 10.6084/m9.figshare.4810960.v1
title: HGT in Bacteroidetes

description: HGT in human gut microbes: Horizontally transferred genes received by Bacteroidetes species.
DOI: 10.6084/m9.figshare.4810927.v1
title: One-dimensional steady-state thermal model for rotary kilns used in the manufacture of cement

description: Rotary kilns are used extensively in the cement industry to convert raw meal into cement clinker. In order to optimise the operation of cement kilns, computationally efficient thermal models are required. In this work, the development of a one-dimensional thermal model for kilns is explored. To simplify the model, the kiln is assumed to be well mixed in the transverse direction. A simultaneous mass and energy balance is solved based on a steady-state approximation. Existing semi-empirical models for heat transfer in the kiln are implemented and critically evaluated. The resulting one-dimensional model is capable of predicting axial temperature profiles in the rotary kiln which agree well with the available experimental data found in the literature. The model presented here extends from previous published models by considering a full enthalpy balance for the gas in the kiln. This allows the model to be used in a fully predictive manner, taking into account the temperature-dependent thermodynamic, transport, and radiative properties of the gas phase.
DOI: 10.6084/m9.figshare.4810873
title: Non-specific adsorption of complement proteins affects complement activation pathways of gold nanomaterials

description: The complement system is a key humoral component of innate immunity, serving as the first line of defense against intruders, including foreign synthetic nanomaterials. Although gold nanomaterials (AuNMs) are widely used in nanomedicine, their immunological response is not well understood. Using AuNMs of three shapes commonly used in biomedical applications: spherical gold nanoparticles, gold nanostars and gold nanorods, we demonstrated that AuNMs activated whole complement system, leading to the formation of SC5b-9 complex. All three complement pathways were simultaneously activated by all the AuNMs. Recognition molecules of the complement system interacted with all AuNMs <i>in vitro</i>, except for l-ficolin, but the correlation between these interactions and corresponding complement pathway activation was only observed in the classical and alternative pathways. We also observed the mediating role of complement activation in cellular uptake of all AuNMs by human U937 promonocytic cells, which expresses complement receptors. Taken together, our results highlighted the potential immunological challenges for clinical applications of AuNMs that were often overlooked.
DOI: 10.6084/m9.figshare.4810873.v1
title: Non-specific adsorption of complement proteins affects complement activation pathways of gold nanomaterials

description: The complement system is a key humoral component of innate immunity, serving as the first line of defense against intruders, including foreign synthetic nanomaterials. Although gold nanomaterials (AuNMs) are widely used in nanomedicine, their immunological response is not well understood. Using AuNMs of three shapes commonly used in biomedical applications: spherical gold nanoparticles, gold nanostars and gold nanorods, we demonstrated that AuNMs activated whole complement system, leading to the formation of SC5b-9 complex. All three complement pathways were simultaneously activated by all the AuNMs. Recognition molecules of the complement system interacted with all AuNMs <i>in vitro</i>, except for l-ficolin, but the correlation between these interactions and corresponding complement pathway activation was only observed in the classical and alternative pathways. We also observed the mediating role of complement activation in cellular uptake of all AuNMs by human U937 promonocytic cells, which expresses complement receptors. Taken together, our results highlighted the potential immunological challenges for clinical applications of AuNMs that were often overlooked.
DOI: 10.15468/gj477u
title: A review of the Indian species formerly assigned to the genus Storena Walckenaer, 1805 (Araneae: Zodariidae) with the description of a new genus

description: This dataset contains the digitized treatments in Plazi based on the original journal article Sankaran, Pradeep M., Caleb, John T. D., Sebastian, Pothalil A. (2020): A review of the Indian species formerly assigned to the genus Storena Walckenaer, 1805 (Araneae: Zodariidae) with the description of a new genus. European Journal of Taxonomy 707: 1-23, DOI: https://doi.org/10.5852/ejt.2020.707
DOI: 10.6084/m9.figshare.4810837
title: Deep genomic analysis of the <i>Chlorella sorokiniana</i> SAG 211-8k chloroplast

description: The chloroplast genome contains information that is applicable in many scientific fields, such as plant systematics, phylogenetic reconstruction and biotechnology, because its features are highly conserved among species. To date, several complete green algal chloroplast genomes have been sequenced and assembled. In this study, the nucleotide sequence of the chloroplast genome (cpDNA) of <i>Chlorella sorokiniana</i> SAG 211-8k is reported and compared for the first time to the chloroplast genomes of 10 Chlorellaceae. The recently updated <i>Chlorella sorokiniana</i> cpDNA sequence, assembled as a circular map of 109 811 bp, encodes 113 genes. Similar to other <i>Chlorella</i> strains, this chloroplast genome does not show a quadripartite structure and lacks the large rRNA operon-encoding Inverted Repeat (IR). The <i>Chlorella sorokiniana</i> plastid encodes the tRNA(Ile)-lysidine synthetase (<i>til</i>S), which is responsible for modifying the CAU anticodon of a unique tRNA. Gene ordering and clustering highlight the close relationships among <i>Chlorella</i> clade members and the preservation of crucial gene clusters in photosynthetic strains. The features of <i>Chlorella sorokiniana</i> presented here reinforce the monophyletic character of Chlorellaceae and provide important information that sheds light on chloroplast genome evolution among species of <i>Chlorella</i>.
DOI: 10.6084/m9.figshare.4810825
title: MOUtbhR RNA-seq mapping assess

description: RNA-seq pipeline analysis of mouse single end libraries.
DOI: 10.6084/m9.figshare.4810825.v1
title: MOUtbhR RNA-seq mapping assess

description: RNA-seq pipeline analysis of mouse single end libraries.
DOI: 10.6084/m9.figshare.4810837.v1
title: Deep genomic analysis of the <i>Chlorella sorokiniana</i> SAG 211-8k chloroplast

description: The chloroplast genome contains information that is applicable in many scientific fields, such as plant systematics, phylogenetic reconstruction and biotechnology, because its features are highly conserved among species. To date, several complete green algal chloroplast genomes have been sequenced and assembled. In this study, the nucleotide sequence of the chloroplast genome (cpDNA) of <i>Chlorella sorokiniana</i> SAG 211-8k is reported and compared for the first time to the chloroplast genomes of 10 Chlorellaceae. The recently updated <i>Chlorella sorokiniana</i> cpDNA sequence, assembled as a circular map of 109 811 bp, encodes 113 genes. Similar to other <i>Chlorella</i> strains, this chloroplast genome does not show a quadripartite structure and lacks the large rRNA operon-encoding Inverted Repeat (IR). The <i>Chlorella sorokiniana</i> plastid encodes the tRNA(Ile)-lysidine synthetase (<i>til</i>S), which is responsible for modifying the CAU anticodon of a unique tRNA. Gene ordering and clustering highlight the close relationships among <i>Chlorella</i> clade members and the preservation of crucial gene clusters in photosynthetic strains. The features of <i>Chlorella sorokiniana</i> presented here reinforce the monophyletic character of Chlorellaceae and provide important information that sheds light on chloroplast genome evolution among species of <i>Chlorella</i>.
DOI: 10.6084/m9.figshare.4810807
title: Behaviour of CD4 and CD8 cells after an in vitro stimulation

description: CD4+ cell behaviour after an in vitro stimulation (tracked with CFSE). Time is in hours.<br><br>Data has been published in Statistical determination of threshold for cellular division in the CFSE-labeling assay, Liu et al. Journal of Immunological Methods, 2006 (doi:10.1016/j.jim.2006.03.010)<br><br>Data has been previously studied in Evaluation of Multitype Mathematical Models for CFSE-Labeling Experiment Data, Miao et al., Belletin of Mathematical Biology, 2012 (DOI 10.1007/s11538-011-9668-y)<br>
DOI: 10.6084/m9.figshare.4810798
title: Camera-trapping and seed-labelling reveals widespread granivory and scatter-hoarding of nuts by rodents in the Fynbos Biome

description: Many plant–animal interactions can be challenging to directly observe, due to species being small, cryptic and/or nocturnal. Previous research on seed predation and dispersal by rodents in the Fynbos Biome of South Africa has relied on indirect evidence, as methods for directly monitoring rodent–seed interactions were not available. The aims of the study were to determine which resident small mammals scatter-hoard nuts and the geographic, seasonal and taxonomic extent of scatter-hoarding in the Fynbos Biome. We used camera traps focused on seed stations at eight sites in the Fynbos Biome to determine the responses of small mammals to tagged nut-like fruits (nuts) of seven endemic plant species belonging to the Proteaceae (<i>n</i> = 3), Rosaceae (<i>n</i> = 2), Restionaceae (<i>n</i> = 1) and Cupressaceae (<i>n</i> = 1), as well as commercial sunflower seeds. We found <i>Acomys subspinosus</i> and <i>Gerbilliscus paeba</i> scatter-hoarded nuts, which they typically carried and buried individually. <i>Rhabdomys pumilio</i> and <i>Micaelamys namaquensis</i> only consumed nuts. <i>Leucadendron pubescens</i> and <i>L. loranthifolium</i> are added to the list of known plant species that are scatter-hoarded by rodents. Nuts of <i>Cliffortia cuneata</i> and <i>C. phillipsii</i>, and the critically endangered <i>Widdringtonia cedarbergensis</i>, were consumed but not dispersed by small mammals, whereas nuts of <i>Ceratocaryum argenteum</i> were neither consumed nor scatter-hoarded by rodents (within its native range). <i>Gerbilliscus paeba</i> and <i>A. subspinosus</i> scatter-hoarded nuts aseasonally, outside of seed-fall periods. Scatter-hoarding was widespread throughout the Fynbos Biome, although it was highly localised across and within sampled sites. The absence of scatter-hoarding rodents at sites with rodent-dispersed plants remains an important aspect for future investigation.
DOI: 10.6084/m9.figshare.4810804
title: European tree mortality information

description: This dataset provides consistent European tree mortality information from 2002 to 2012.Description of dataset:id_plot ... ID of plot<br>lat_MODIS ... latitude of centerpoint of corresponding cell of MODIS grid, in degrees using WGS84, accuracy 1 km<br>lon_MODIS ... longitude of centerpoint of MODIS cell, see above<br>id_plot ... ID of tree<br>year ... year of observation of trees status<br>species ... tree species group of tree: 1 pioneer conifers, 2 shade tolerant conifers, 3 mediterranean conifers, 4 fast growing deciduous, 5 light demanding broadleaf, 6 shade tolerant broadleaf, 7 evergreen broadleaf, 9 unclassified<br>age ... age class of forest stand: 1 0-20 years, 2 21-40 years, 3 41-60 years, 4 61-80 years, 5 81-100 years, 6 101-120 years, 7 &gt;120 years<br>status ... status of tree: 0 alive, 1 dead<br><br>The file contains processed results derived using tree data from the ICP Forests database with falsified locations centered using the grid system of MODIS satellite data. For access to the original data please contact the data holder, ICP Forests (http://icp-forests.net/).<br><br>This analysis is based on data collected by partners of the official UNECE ICP Forests Network (http://icp-forests.net/contributors). Part of the data was co-financed by the European Commission (data received on 05.12.2015).<br>For details see the corresponding scientific publication.<br>Neumann, M., Mues, V., Moreno, A., Hasenauer, H., Seidl, R. (2017). Climate variability drives recent tree mortality in Europe. Global Change Biology. 10.1111/gcb.13724
DOI: 10.6084/m9.figshare.4810816
title: Context, Continuity, Correspondence, and Continental Connections: New Approaches to the Ironwork Hoards of Roman Britain

description: For over forty years the study of Roman ironwork hoards in Britain has been defined by a single study by Manning (1972). This article summarizes the wealth of advances made since that publication regarding the distribution, context, and contents of these hoards, highlighting how these alter our understanding of them as a continuation of Iron Age practices. Furthermore, by looking at British hoards at a European level for the first time, we see that British and Continental hoards are closely related. Using Correspondence Analysis to produce new groupings based on content, which crosscut those proposed by Manning (1972) based on distribution, the article provides the first analysis of the entire contents of these hoards. Finally, a discussion of hoard contents is used to examine the potential significance of the artefacts deposited.