cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.6969593.v1
title: Supplementary Material for: Uric Acid as a Predictor of Immunoglobulin A Nephropathy Progression: A Cohort Study of 1965 Cases

description: <b><i>Background:</i></b> The role of serum uric acid (SUA) level in the progression of Immunoglobulin A nephropathy (IgAN) remains controversial. <b><i>Methods:</i></b> In a cohort of 1,965 cases with biopsy-proven IgAN, we examined the associations of SUA concentration with the primary outcome of a composite of all-cause mortality or kidney failure (defined as a reduction of estimated glomerular filtration rate [eGFR] by 40% from baseline, requirements for dialysis and transplantation), or the outcome of kidney failure alone, assessed using Cox and logistic regression models, respectively, with adjustment for confounders. <b><i>Results:</i></b> At baseline, the mean age was 33.37 ± 11.07 years, eGFR was 101.30 ± 30.49 mL/min/1.73 m<sup>2</sup>, and mean uric acid level was 5.32 ± 1.76 mg/dL. During a median of 7-year follow-up, 317 cases reached the composite outcome of all-cause mortality (5 deaths) or kidney failure (36 cases of dialysis, 5 cases of renal transplantation, and 271 cases with reduction of eGFR by 40% from baseline). After adjustment for demographic and IgAN specific covariates and treatments, a higher quartile of uric acid was linearly associated with an increased risk of the primary outcome (highest versus lowest quartile, hazard ratio [HR] 2.39; 95% CI 1.52–3.75) and kidney failure (highest versus lowest quartile, HR 2.55; 95% CI 1.62–4.01) in the Cox proportional hazards regression models. In the continuous analysis, a 1 mg/dL greater uric acid level was associated with 16% increased risk of primary outcome (HR 1.16, 95% CI 1.07–1.25) and 17% increased risk of kidney failure (HR 1.17, 95% CI 1.08–1.27), respectively, in the fully adjusted model. The multivariate ­logistic regression analyses for the sensitive analyses drew consistent results. In the subgroup analyses, significant interactions were detected that patients with mean arterial pressure (MAP) &lt; 90 mm Hg or mesangial hypercellularity had a higher association of SUA with the incidence of the primary outcome than those with MAP ≥90 mm Hg or those without mesangial hypercellularity respectively. Hyperuricemia was not significantly associated with the risk of developing the primary outcome in elder patients (≥32 years old), patients with eGFR &lt; 90 mL/min or with tubular atrophy/interstitial fibrosis. <b><i>Conclusions:</i></b> SUA level may be positively associated with the progression of IgAN. It was noticeable that the association of hyperuricemia with IgAN progression was less significant in patients with elder age, lower eGFR, or tubular atrophy/interstitial fibrosis, which may be due to some more confounders in association with the IgA progression in these patients. Future prospective studies are warranted to confirm these findings and to investigate the underlying mechanisms.
DOI: 10.17632/5j7brtkktv
title: Zebra fecal egg counts

description: In wildlife, endoparasite burden can be strongly affected by host life-history stage, environmental conditions, host abundance, and parasite co-infections. We tested the effects of these factors on gastrointestinal parasite infection in plains zebras (Equus quagga) in the Serengeti ecosystem, Tanzania, using fecal egg counts of two nematode families (Strongylidae and Ascarididae) and on the presence/absence of cestode (Anoplocephalidae) eggs. We predicted higher egg counts of Strongylidae and Ascarididae and increased likelihood of Anoplocephalidae infection in individuals 1) during energetically costly life history stages when resource allocation to immune processes may decrease and in young zebras after weaning because of increased uptake of infective stages with forage, 2) when climatic conditions facilitate survival of infective stages, 3) during times of large aggregations when forage contamination with infective stages increases, and 4) in individuals co-infected with more than one of these parasites, as this may indicate reduced immune competence. Strongylidae egg counts were higher and occurrence of Anoplocephalidae eggs was more likely in bachelors than in band stallions, whereas Ascarididae egg counts were higher in band stallions. Strongylidae and Ascarididae egg counts were not affected by lactation in adult females or by age class in young. In adult males, adult females, and young, Ascarididae infections were more likely in wet conditions. Co-infections did not affect Strongylidae egg counts. Ascarididae egg counts in adult females were higher when individuals were co-infected with Anoplocephalidae. We present evidence that parasite burdens in plains zebras are affected by life history stage, environmental conditions, and co-infection.
DOI: 10.17632/wfdp6t7v2f
title: Artificial Intelligence in Medicine: Revolutionizing Healthcare Practices and Patient Outcomes

description: Abstract
Artificial intelligence (AI) has transformed medicine, advancing diagnostics, treatment, and patient outcomes. This study employs bibliometric analysis and the PRISMA framework to explore AI research trends in medicine from 2019 to 2023. Key findings reveal significant growth in publications, with radiomics, genomics, and predictive analytics as major focus areas. Federated learning frameworks and wearable technologies emerge as critical innova-tions, addressing challenges such as data privacy and real-time monitoring. Despite these advancements, significant barriers persist, including algorithmic bias, data confidentiality, and the need for infrastructure and training to integrate AI into clinical workflows. Future directions emphasize the importance of interdisciplinary collaboration, ethical AI develop-ment, and explainable models to ensure trust and equitable access. By addressing these chal-lenges, AI has the potential to revolutionize healthcare systems, optimize resource alloca-tion, and enhance personalized medicine. This study highlights the transformative role of AI in shaping the future of medicine and improving global health outcomes.

Keywords: Artificial Intelligence, Personalized Medicine, Healthcare Innovation, AI-Driven Diagnostics, Machine Learning, Deep Learning, Predictive Analytics
DOI: 10.6084/m9.figshare.11312171.v1
title: Supplementary Table S1 List of primers for real-time PCR.docx

description: List of primers for real-time PCR
DOI: 10.6084/m9.figshare.11704242.v1
title: Patient 5

description: Atrial Flutter patient #1Part 1 contains the raw ultrasound RF dataPart 2 contains the B-mode, multi-2D and 3D-rendered EWI activation timings
DOI: 10.6084/m9.figshare.14986725.v1
title: Supplementary Material for: An Apparently Balanced Complex Chromosome Rearrangement Involving Seven Breaks and Four Chromosomes in a Healthy Female and Segregation/Recombination in Her Affected Son

description: Duplication of the distal 1q and 4p segments are both characterized by the presence of intellectual disability/neurodevelopmental delay and dysmorphisms. Here, we describe a male with a complex chromosome rearrangement (CCR) presenting with overlapping clinical findings between these 2 syndromes. In order to better characterize this CCR, classical karyotyping, FISH, and chromosomal microarray analysis were performed on material from the patient and his parents, which revealed an unbalanced karyotype with duplications at 1q41q43 and 4p15.2p14 in the proband. The rearrangements, which were derived from a maternal balanced karyotype, included an insertion of a segment from the long to the short arm of chromosome 1, a balanced translocation involving chromosomes 14 and 18, and an insertion of a segment from the short arm of chromosome 4 into the derived chromosome 14. This study aimed to better define the clinical history and prognosis of a patient with this rare category of chromosomal aberration. Our results suggest that the frequency of CCR in the general population may be underestimated; when balanced, they may not have a phenotypic effect. Moreover, they emphasize the need for cytogenetic techniques complementary to chromosomal microarray for proper genetic counseling.
DOI: 10.6084/m9.figshare.7514267.v1
title: Influence of agitation intensity on flotation rate of apatite particles

description: Abstract The agitation intensity has a directly influence on flotation performance, lifting the particles and promoting the contact of bubbles and particles. In this paper, the energy input by the agitation on apatite flotation was investigated. The influence of pulp agitation in the flotation rate of particles with different sizes and two dosage levels was evaluated by batch testing. The flotation tests were conducted in an oscillating grid flotation cell (OGC), developed to promote a near isotropic turbulence environment. The cell is able to control the intensity of agitation and measure the energy transferred to the pulp phase. A sample of pure apatite was crushed (P80=310µm), characterized and floated with sodium oleate as collector. Four levels of energy dissipation, from 0.1 to 2 kWm-3, and two levels of collector dosage are used during the tests. The flotation kinetics by particle size were determined in function of the energy transferred. The results show a strong influence of the agitation intensity on the apatite flotation rate with both low and high dosage. For fine particles, when increasing the energy input, the flotation rate increase too, and this fact can be attributed to elevation of bubble-particle collisions. The kinetic result for the coarse particles demonstrated a reduction of the flotation rate whenever the energy input for this particle size was increased, whereby the turbulence caused by the agitation promotes the detachment of bubble-particle.
DOI: 10.15468/dl.hcrbe8
title: Occurrence Download

description: A dataset containing 433 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Observation, Human Observation, Machine Observation, Living Specimen)"
 ]
 }
 },
 "TaxonKey is Acleris cristana (Denis & Schiffermüller), 1775"
 ]
}

 The dataset includes 433 records from 29 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0009384-250426092105405/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.17632/tmn5n9h9p9
title: Data for: Meta-modeling game for deriving theoretical-consistent, micro-structural-based traction-separation laws via deep reinforcement learning

description: Data generated from DEM assembles used in the meta-modeling algorithm.
DOI: 10.17632/2pxgf95y43
title: Risk-free rate of return in Sweden 2010-2018

description: Year-month and risk-free rate of return (in %), collected from Nasdaq.
DOI: 10.6084/m9.figshare.12696437.v1
title: Supplementary Material for: The Burden and Trends of Primary Liver Cancer Caused by Specific Etiologies from 1990 to 2017 at the Global, Regional, National, Age, and Sex Level Results from the Global Burden of Disease Study 2017

description: <b><i>Background:</i></b> Liver cancer is one of the leading causes of cancer-related deaths worldwide. The primary causes of liver cancer include hepatitis B virus (HBV), hepatitis C virus (HCV), alcohol consumption, nonalcoholic fatty liver disease, and other factors. <b><i>Aims:</i></b> The objective of this study was to evaluate the global and sex-, age-, region-, country-, and etiology-related liver cancer burden, as well as the trends in liver cancer caused by different etiologies. <b><i>Methods:</i></b> The causes of liver cancer from 1990 to 2017, including global, regional, and national liver cancer incidence, mortality, and etiology, were collected from the Global Burden of Disease study 2017, and the time-dependent change in the trends of liver cancer burden was evaluated by annual percentage change. <b><i>Results:</i></b> The global liver cancer incidence and mortality have been increasing. There were 950,000 newly-diagnosed liver cancer cases and over 800,000 deaths in 2017, which is more than twice the numbers recorded in 1990. HBV and HCV are the major causes of liver cancer. HBV is the major risk factor of liver cancer in Asia, while HCV and alcohol abuse are the major risk factors in the high sociodemographic index and high human development index regions. The mean onset age and incidence of liver cancer with different etiologies have gradually increased in the past 30 years. <b><i>Conclusions:</i></b> The global incidence is still rising and the causes have national, regional, or population specificities. More targeted prevention strategies must be developed for the different etiologic types in order to reduce liver cancer burden.
DOI: 10.6084/m9.figshare.27178287.v1
title: DATA.xlsx

description: Evaluation of the Vaginal Panel Realtime PCR Kit (Vircell, SL) for diagnosing vaginitis: A comparative study with routinely used diagnosticsThe study aims to assess the efficacy and accuracy of a molecular diagnostic test in comparison to routinely used diagnostic methods for detecting three common vaginal infections: bacterial vaginosis (BV), vulvovaginal candidiasis (VVC), and trichomoniasis.
DOI: 10.6084/m9.figshare.20189891.v1
title: Supplementary Material for: Developmental Trajectories of Self-, Other-, and Dual-Harm across Adolescence: The Role of Relationships with Peers and Teachers

description: <b><i>Introduction:</i></b> We investigated the longitudinal course of self-, other-, and dual-harm in adolescents, focusing on the infliction of physical injury on oneself, another person, or both parties, respectively. We examined the within-person transitions between these types of harm and whether relationships with peers and teachers predict individual harm trajectories. <b><i>Methods:</i></b> We used community-representative longitudinal data (<i>N</i> = 1,482; 52% male; 50% both parents born abroad). The participants self-reported self- and other-harm at 13, 15, 17, and 20 years. We assigned them to groups with self-, other-, dual- or no harm at specific assessments. Bullying victimization and relationship quality with classmates and teachers were assessed at 13 and 17. We estimated transition probabilities between the harm groups using latent Markov chain models. <b><i>Results:</i></b> At age 13, 3% of the sample engaged in dual-harm, 10% in self-harm only, and 7% in other-harm only. These percentages decreased in late adolescence. Initial dual-harm was often followed by sex-specific single-harm: most of the female participants transitioned to self-harm, and male participants to other-harm. Those in the initial dual-harm group were less likely to stop harming than those in the initial single-harm groups (<i>p</i> &lt; 0.05). Adverse relationship experiences generally predicted harm. A positive teacher-student bond was associated with the cessation of single-harm. <b><i>Conclusion:</i></b> Single- and dual-harm in the form of physical injury typically emerge by mid-adolescence. After this point, adolescents commonly maintain harm, especially those who have presented with dual-harm. Helping adolescents cope with adverse relationship experiences and creating opportunities for positive relationship experiences could address these harmful behaviors.
DOI: 10.6084/m9.figshare.7897925.v1
title: gVCF_HG03271

description: 1000 Genomes gVCF mapped to hs37d5 for HG03271. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307
DOI: 10.6084/m9.figshare.23936097.v1
title: Supplementary Material for: Intravitreal triamcinolone acetonide for diabetic macular edema and macular edema secondary to retinal vein occlusion: a meta-analysis

description: Background: The comparative safety and efficacy of different doses of intravitreal triamcinolone acetonide (IVTA) for diabetic macular edema (DME) and macular edema (ME) secondary to retinal vein occlusion (RVO) is unclear. Objectives: This meta-analysis aimed to compare the safety and efficacy of different doses of IVTA in this setting. Methods: A systematic literature search for randomized clinical trials (RCTs) was conducted on Cochrane Library, Ovid MEDLINE and EMBASE from January 2005 to May 2022. Studies reporting on patients with DME or ME secondary to RVO that received treatment with different doses of IVTA. A random effects meta-analysis was performed. Cochrane’s risk of bias tool 2 was used to assess the risk of bias and grading of recommendations, assessment, development and evaluation (GRADE) guidelines were used to assess certainty of evidence. Results: Five RCTs reporting on 1,041 eyes at baseline were included in this meta-analysis. In eyes with ME secondary to RVO, high dose (4 mg) IVTA achieved a significantly better change in best-corrected visual acuity (WMD=-4.75 ETDRS letters, 95%CI=[-7.73, -1.78], p=.002) and reduction in retinal thickness (WMD=-93.02 µm, 95%CI=[-153.23, -32.82], p=.002) at months 4-6 compared to low dose (1-2 mg) IVTA. However, high dose IVTA had a higher risk of intraocular pressure (IOP)-related adverse events (RR=2.99, 95%CI=[1.05, 8.50], p=.04) and cataract surgery (RR=5.67, 95%CI=[3.09, 10.41], p&lt;.00001) than low dose IVTA in eyes with ME secondary to RVO. These efficacy and safety differences in high dose and low dose IVTA were not observed in DME eyes. Conclusions: The RCT evidence in this setting is limited. High dose IVTA achieved greater improvements in visual acuity and reductions in retinal thickness than low dose IVTA at months 4-6. However, high dose IVTA had a less favourable safety profile than low dose IVTA. The significance of these outcomes was based on patients with ME secondary to RVO, but not DME.
DOI: 10.6084/m9.figshare.28303454.v1
title: Supplementary Material for: Hidden Resources for Cancer Patients – Interactions between spirituality, religiosity and selected factors influencing patient’s self-care

description: Introduction. Religiosity and spirituality (SpR) can be vital in helping people face life's challenges. While Spiritual Care (SpC) is used in palliative care, this study explores effects for cancer patient’s self-care (SC) in earlier stages . 
Methods. Using validated instruments we surveyed patients about SpR (SpNQ-20, GrAw-7, SpREUK), and factors of SC: well-being (WHO-5, L-1), self-efficacy (ASKU), ability to change (PIAC), as well as lay etiology and the use of Complementary and alternative Medicine (CAM). Data were analyzed using SPSS according a three-step plan with descriptive methods, Spearman correlations and mediation analysis.
Results. We included 108 patients (41 female, 63 males, four no data) with a median age of 66 years (range 30-89). Welch tests show a less well-being, self-efficacy and ability to change in our study population (p &lt; 0.05) compared to non-cancer controls. Whitney-U-test has documented increased well-being, CAM use if the patients were S/R+ (p &lt; 0.05). S/R self-categorization had no impact on PIAC and ASKU. Perceptual spirituality (GrAw-7) correlates with all factors of SC (p &lt; 0.05): WHO-5 (rs = 0.25), PIAC (rs = 0.25), ASKU (rs = 0.296), L-1 (rs = 0.35) and CAM use (rs = 0.39, p &lt; 0.001). Mediation analysis demonstrates that the impact of Spirituality on self-care (CAM use) is mediated by religiosity, GrAw-7 and spiritual needs. 
Conclusion. Spirituality and hidden spiritual needs are a valuable resource. By integrating SpC early in the treatment, we can create support ways and improve SC, well-being and coping.
DOI: 10.17632/3zzkvnj3sk
title: Design of a Dual Screening Tool for the Detection of Fungi and Mycotoxins in Stored Cocoa

description: This data is centered on the development of a cell-free screening method to identify mycotoxins and fungi in stored cocoa beans, addressing a critical gap in local knowledge about fungal contamination. Utilizing computational tools like Benchling for cassette design and AlphaFold for protein modeling, we identified cross-activity with Aflatoxin, specifically Gliotoxin and ABA. The constructed cassettes, featuring chimeric proteins Bichota and X19X, were validated through AlphaFold modeling, and their interactions with target molecules and natural components in healthy cacao were explored via Docking and Virtual Screening using SwissDock. The data suggests that our screening method has the potential to empower cocoa producers by providing real-time information to prevent economic losses due to fungal contamination and mycotoxin production. Furthermore, the application of this technology aligns with international market standards, ensuring compliance with maximum permissible limits of mycotoxins for cocoa exports according to European Union legislation. The success of this project could significantly contribute to strengthening the cocoa value chain, improving product quality, and expanding opportunities in global markets.
DOI: 10.6084/m9.figshare.13323431.v1
title: 元数据描述.docx

description: d对新冠疫情期间电商订单数据进行综合分析
DOI: 10.6084/m9.figshare.13489215.v1
title: PerPlex EEG.zip

description: ERP experiment with eight healthy participants during color textural perception of natural and fractal images followed byreasoning on their complexity degree, against single color reference images. Recorded data: 5 neural channels by Biopac wireless EEG system.<br>Please, cite related paper:Nicolae, I.E.; Ivanovici, M. Preparatory Experiments Regarding Human Brain Perception and Reasoning of Image Complexity for Synthetic Color Fractal and Natural Texture Images via EEG. Appl. Sci. 2021, 1, 0. https://dx.doi.org/10.3390/app1010000<br><br>
DOI: 10.6084/m9.figshare.19499405.v1
title: patches and local annotations, slide 029, zoom 248x248 um2

description: patches and local annotations: data for slide with ID of the last 3 characters of the file name: local annotations in csv format and a folder with patches at zoom level indicated at the 6th character of the file name