cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.4117555
title: Mapping GPIIb/IIIa on murine blood platelets with expansion microscopy

description: <strong>Mapping GPIIb/IIIa on murine blood platelets with expansion microscopy</strong> We visualize the membrane architecture of platelets by mapping platelet integrin GPIIb/IIIa by super-resolution fluorescence. Our approach combines colocalization and expansion microscopy and successfully interrogates highly abundant receptors and their interactions where conventional methods fail in such dense 3D scenarios (https://doi.org/10.1101/2021.02.16.431449) Here we provide a s<em>election of typical images</em> of receptor distributions on unexpanded and expanded murine platelets, the <em>code</em> for simulation of platelet receptor distributions including a <em>user manual </em>and a <em>video protocol </em>of 10x expansion microscopy with resting platelets. <strong>Sample images: </strong> Unexpanded, 4x expanded and 10x expanded resting murine platelets on glycine coated coverslips were imaged on a SP5 confocal microscope (detailed methods can be found in the manuscript). There are three different labeling combinations: Case I: directly immunolabeled with monoclonal antibodies antibodies carrying Alexa Fluor 488 (MWReg30, green channel) or Alexa Fluor 594 (JON6, magenta channel) can bind simultaneously on the same GPIIb/IIIa receptor -&gt; high colocalization Case II: directly immunolabeled with a monoclonal antibody targeting GPIIb/IIIa (MWReg30) carrying either Alexa Fluor 594 or Alexa Fluor 488) -&gt; low colocalizaiton Case III: directly immunolabeld with monoclonal antibodies carrying Alexa Fluor 488 targeting GPIIb/IIIa (JON6) and carrying Alexa Fluor 594 targeting GPIX (p0p6) -&gt; low colocalization The provided sample images are .ims (Imaris) files contain the raw data, chromatic aberration corrected data & deconvolved data as consecutive time points, as well as the cropped image stack of a single platelet with the masked data used for colocalization analysis. <strong>MatLab Scipts: 3D-Image simulation of Platelet Receptor Distributions</strong> The provided MatLab scripts allow to create 2-color, 3D image stacks based on simulated platelet receptor distributions and the image resolution provided by confocal microscopy and sample expansion. Refer to the user manual for a detailed description of how to set up and run the simulation. <strong>Video Protocol:</strong> <strong>10x expansion microscopy with resting platelets.</strong> The provided video protocol describes the sample preperation for 10x expansion microscopy of resting platelets, including platelet washing, immunolabeling, gelation, digestion, expansion and sample mounting for imaging. Detailed step by step protocols are also provided in the supplementary material (https://doi.org/10.1101/2021.02.16.431449).
DOI: 10.5281/zenodo.5185399
title: Data for "Learning from mistakes - Assessing the performance and uncertainty in process-based models"

description: <strong>Data for the publication "Learning from mistakes - Assessing the performance and uncertainty in process-based models"</strong> The corresponding python code can be found at github.com/MoritzFeigl/Learning-from-mistakes. This dataset contains data of hydrological and meteorological observations of the Fortress Ski Area (Alberta, Canada) for August 8-26, 2019. It consists of input and output files for the HFLUX models calibration period (C) and the validation periods (V, V3). The input files containes additional data used in the learning from mistakes workflow. The meteorological data and part of the hydrological data were provided by John Pomeroy and the University of Saskatchewan’s Cold Water Laboratory.
DOI: 10.5281/zenodo.5185398
title: Data for "Learning from mistakes - Assessing the performance and uncertainty in process-based models"

description: <strong>Data for the publication "Learning from mistakes - Assessing the performance and uncertainty in process-based models"</strong> The corresponding python code can be found at github.com/MoritzFeigl/Learning-from-mistakes. This dataset contains data of hydrological and meteorological observations of the Fortress Ski Area (Alberta, Canada) for August 8-26, 2019. It consists of input and output files for the HFLUX models calibration period (C) and the validation periods (V, V3). The input files containes additional data used in the learning from mistakes workflow. The meteorological data and part of the hydrological data were provided by John Pomeroy and the University of Saskatchewan’s Cold Water Laboratory.
DOI: 10.6084/m9.figshare.15155967
title: Supplementary Material for: How Dialysis Patients Cope with a Curfew? A Comparison of Psychological Status between Hemodialysis and Peritoneal Dialysis Patients During the COVID-19 Pandemic

description: <b><i>Introduction:</i></b> There are many differences between hemodialysis (HD) and peritoneal dialysis (PD) treatments, including their impact on the psychological status of the patients. In this study, our aim was to compare the psychological statuses of HD and PD patients during the social isolation period due to the COVID-19 pandemic. <b><i>Methods:</i></b> We conducted this cross-sectional study on adult HD and PD patients when the curfew measures were in effect. We used an electronic form composed of 3 sections to collect data. In the first section, we collected data on the demographics and clinical and laboratory parameters of the patients. The second and third sections consisted of the Hospital Anxiety and Depression Scale (HADS) and the Impact of Event Scale-Revised (IES-R) questionnaires, respectively. <b><i>Results:</i></b> The HD (<i>n</i> = 116) and PD (<i>n</i> = 130) groups were similar regarding age and sex, and they had similar HADS anxiety scores. HADS depression scores were higher in PD patients (<i>p</i> = 0.052). IES-R scores were significantly higher in PD patients in comparison to HD patients (<i>p</i> = 0.001). Frequencies of abnormal HADS-anxiety (<i>p</i> = 0.035) and severe psychological impact (<i>p</i> = 0.001) were significantly higher in PD patients. <b><i>Discussion/Conclusion:</i></b> During the social isolation period due to the COVID-19 pandemic, HD patients had better mood profiles than PD patients. A more stable daily routine, an uninterrupted face-to-face contact with health-care workers, and social support among patients in the in-center dialysis environment might be the cause of the favorable mood status. PD patients might need additional psychological support during those periods.
DOI: 10.6084/m9.figshare.14891307
title: Supplementary Material for: Axolotls’ and Mice’s Oral-Maxillofacial Trephining Wounds Heal Differently

description: Medicine
DOI: 10.6084/m9.figshare.15155981.v1
title: Titanokorys_ldk.tnt from A giant nektobenthic radiodont from the Burgess Shale and the significance of hurdiid carapace diversity

description: Radiodonts, stem-group euarthropods that evolved during the Cambrian explosion, were among the largest and most diversified lower palaeozoic predators. These animals were widespread geographically, occupying a variety of ecological niches, from benthic foragers to nektonic suspension feeders and apex predators. Here, we describe the largest Cambrian hurdiid radiodont known so far, <i>Titanokorys gainesi</i>, gen. et sp. nov., from the Burgess Shale (Marble Canyon, Kootenay National Park, British Columbia). Estimated to reach half-a-meter in length, this new species bears a very large ovoid-shaped central carapace with distinct short posterolateral processes and an anterior spine. Geometric morphometric analyses highlight the high diversity of carapace shapes in hurdiids and show that <i>Titanokorys</i> bridges a morphological gap between forms with long and short carapaces. Carapace shape, however, is prone to homoplasy and shows no consistent relationship with trophic ecology, as demonstrated by new data, including a reappraisal of the poorly known <i>Pahvantia</i>. Despite distinct carapaces, <i>Titanokorys</i> shares similar rake-like appendages for sediment-sifting with <i>Cambroraster,</i> a smaller but much more abundant sympatric hurdiid from the Burgess Shale<i>.</i> The co-occurrence of these two species on the same bedding planes highlights the potential competition for benthic resources and the high diversity of large predators sustained by Cambrian communities.
DOI: 10.6084/m9.figshare.15155981
title: Titanokorys_ldk.tnt from A giant nektobenthic radiodont from the Burgess Shale and the significance of hurdiid carapace diversity

description: Radiodonts, stem-group euarthropods that evolved during the Cambrian explosion, were among the largest and most diversified lower palaeozoic predators. These animals were widespread geographically, occupying a variety of ecological niches, from benthic foragers to nektonic suspension feeders and apex predators. Here, we describe the largest Cambrian hurdiid radiodont known so far, <i>Titanokorys gainesi</i>, gen. et sp. nov., from the Burgess Shale (Marble Canyon, Kootenay National Park, British Columbia). Estimated to reach half-a-meter in length, this new species bears a very large ovoid-shaped central carapace with distinct short posterolateral processes and an anterior spine. Geometric morphometric analyses highlight the high diversity of carapace shapes in hurdiids and show that <i>Titanokorys</i> bridges a morphological gap between forms with long and short carapaces. Carapace shape, however, is prone to homoplasy and shows no consistent relationship with trophic ecology, as demonstrated by new data, including a reappraisal of the poorly known <i>Pahvantia</i>. Despite distinct carapaces, <i>Titanokorys</i> shares similar rake-like appendages for sediment-sifting with <i>Cambroraster,</i> a smaller but much more abundant sympatric hurdiid from the Burgess Shale<i>.</i> The co-occurrence of these two species on the same bedding planes highlights the potential competition for benthic resources and the high diversity of large predators sustained by Cambrian communities.
DOI: 10.6084/m9.figshare.15155990
title: P_all_ldk.tps from A giant nektobenthic radiodont from the Burgess Shale and the significance of hurdiid carapace diversity

description: Radiodonts, stem-group euarthropods that evolved during the Cambrian explosion, were among the largest and most diversified lower palaeozoic predators. These animals were widespread geographically, occupying a variety of ecological niches, from benthic foragers to nektonic suspension feeders and apex predators. Here, we describe the largest Cambrian hurdiid radiodont known so far, <i>Titanokorys gainesi</i>, gen. et sp. nov., from the Burgess Shale (Marble Canyon, Kootenay National Park, British Columbia). Estimated to reach half-a-meter in length, this new species bears a very large ovoid-shaped central carapace with distinct short posterolateral processes and an anterior spine. Geometric morphometric analyses highlight the high diversity of carapace shapes in hurdiids and show that <i>Titanokorys</i> bridges a morphological gap between forms with long and short carapaces. Carapace shape, however, is prone to homoplasy and shows no consistent relationship with trophic ecology, as demonstrated by new data, including a reappraisal of the poorly known <i>Pahvantia</i>. Despite distinct carapaces, <i>Titanokorys</i> shares similar rake-like appendages for sediment-sifting with <i>Cambroraster,</i> a smaller but much more abundant sympatric hurdiid from the Burgess Shale<i>.</i> The co-occurrence of these two species on the same bedding planes highlights the potential competition for benthic resources and the high diversity of large predators sustained by Cambrian communities.
DOI: 10.6084/m9.figshare.15155990.v1
title: P_all_ldk.tps from A giant nektobenthic radiodont from the Burgess Shale and the significance of hurdiid carapace diversity

description: Radiodonts, stem-group euarthropods that evolved during the Cambrian explosion, were among the largest and most diversified lower palaeozoic predators. These animals were widespread geographically, occupying a variety of ecological niches, from benthic foragers to nektonic suspension feeders and apex predators. Here, we describe the largest Cambrian hurdiid radiodont known so far, <i>Titanokorys gainesi</i>, gen. et sp. nov., from the Burgess Shale (Marble Canyon, Kootenay National Park, British Columbia). Estimated to reach half-a-meter in length, this new species bears a very large ovoid-shaped central carapace with distinct short posterolateral processes and an anterior spine. Geometric morphometric analyses highlight the high diversity of carapace shapes in hurdiids and show that <i>Titanokorys</i> bridges a morphological gap between forms with long and short carapaces. Carapace shape, however, is prone to homoplasy and shows no consistent relationship with trophic ecology, as demonstrated by new data, including a reappraisal of the poorly known <i>Pahvantia</i>. Despite distinct carapaces, <i>Titanokorys</i> shares similar rake-like appendages for sediment-sifting with <i>Cambroraster,</i> a smaller but much more abundant sympatric hurdiid from the Burgess Shale<i>.</i> The co-occurrence of these two species on the same bedding planes highlights the potential competition for benthic resources and the high diversity of large predators sustained by Cambrian communities.
DOI: 10.6084/m9.figshare.15155993.v1
title: Titanokorys_noc.tnt from A giant nektobenthic radiodont from the Burgess Shale and the significance of hurdiid carapace diversity

description: Radiodonts, stem-group euarthropods that evolved during the Cambrian explosion, were among the largest and most diversified lower palaeozoic predators. These animals were widespread geographically, occupying a variety of ecological niches, from benthic foragers to nektonic suspension feeders and apex predators. Here, we describe the largest Cambrian hurdiid radiodont known so far, <i>Titanokorys gainesi</i>, gen. et sp. nov., from the Burgess Shale (Marble Canyon, Kootenay National Park, British Columbia). Estimated to reach half-a-meter in length, this new species bears a very large ovoid-shaped central carapace with distinct short posterolateral processes and an anterior spine. Geometric morphometric analyses highlight the high diversity of carapace shapes in hurdiids and show that <i>Titanokorys</i> bridges a morphological gap between forms with long and short carapaces. Carapace shape, however, is prone to homoplasy and shows no consistent relationship with trophic ecology, as demonstrated by new data, including a reappraisal of the poorly known <i>Pahvantia</i>. Despite distinct carapaces, <i>Titanokorys</i> shares similar rake-like appendages for sediment-sifting with <i>Cambroraster,</i> a smaller but much more abundant sympatric hurdiid from the Burgess Shale<i>.</i> The co-occurrence of these two species on the same bedding planes highlights the potential competition for benthic resources and the high diversity of large predators sustained by Cambrian communities.
DOI: 10.6084/m9.figshare.15155996
title: H_all_ldk.tps from A giant nektobenthic radiodont from the Burgess Shale and the significance of hurdiid carapace diversity

description: Radiodonts, stem-group euarthropods that evolved during the Cambrian explosion, were among the largest and most diversified lower palaeozoic predators. These animals were widespread geographically, occupying a variety of ecological niches, from benthic foragers to nektonic suspension feeders and apex predators. Here, we describe the largest Cambrian hurdiid radiodont known so far, <i>Titanokorys gainesi</i>, gen. et sp. nov., from the Burgess Shale (Marble Canyon, Kootenay National Park, British Columbia). Estimated to reach half-a-meter in length, this new species bears a very large ovoid-shaped central carapace with distinct short posterolateral processes and an anterior spine. Geometric morphometric analyses highlight the high diversity of carapace shapes in hurdiids and show that <i>Titanokorys</i> bridges a morphological gap between forms with long and short carapaces. Carapace shape, however, is prone to homoplasy and shows no consistent relationship with trophic ecology, as demonstrated by new data, including a reappraisal of the poorly known <i>Pahvantia</i>. Despite distinct carapaces, <i>Titanokorys</i> shares similar rake-like appendages for sediment-sifting with <i>Cambroraster,</i> a smaller but much more abundant sympatric hurdiid from the Burgess Shale<i>.</i> The co-occurrence of these two species on the same bedding planes highlights the potential competition for benthic resources and the high diversity of large predators sustained by Cambrian communities.
DOI: 10.6084/m9.figshare.15155996.v1
title: H_all_ldk.tps from A giant nektobenthic radiodont from the Burgess Shale and the significance of hurdiid carapace diversity

description: Radiodonts, stem-group euarthropods that evolved during the Cambrian explosion, were among the largest and most diversified lower palaeozoic predators. These animals were widespread geographically, occupying a variety of ecological niches, from benthic foragers to nektonic suspension feeders and apex predators. Here, we describe the largest Cambrian hurdiid radiodont known so far, <i>Titanokorys gainesi</i>, gen. et sp. nov., from the Burgess Shale (Marble Canyon, Kootenay National Park, British Columbia). Estimated to reach half-a-meter in length, this new species bears a very large ovoid-shaped central carapace with distinct short posterolateral processes and an anterior spine. Geometric morphometric analyses highlight the high diversity of carapace shapes in hurdiids and show that <i>Titanokorys</i> bridges a morphological gap between forms with long and short carapaces. Carapace shape, however, is prone to homoplasy and shows no consistent relationship with trophic ecology, as demonstrated by new data, including a reappraisal of the poorly known <i>Pahvantia</i>. Despite distinct carapaces, <i>Titanokorys</i> shares similar rake-like appendages for sediment-sifting with <i>Cambroraster,</i> a smaller but much more abundant sympatric hurdiid from the Burgess Shale<i>.</i> The co-occurrence of these two species on the same bedding planes highlights the potential competition for benthic resources and the high diversity of large predators sustained by Cambrian communities.
DOI: 10.6084/m9.figshare.15155993
title: Titanokorys_noc.tnt from A giant nektobenthic radiodont from the Burgess Shale and the significance of hurdiid carapace diversity

description: Radiodonts, stem-group euarthropods that evolved during the Cambrian explosion, were among the largest and most diversified lower palaeozoic predators. These animals were widespread geographically, occupying a variety of ecological niches, from benthic foragers to nektonic suspension feeders and apex predators. Here, we describe the largest Cambrian hurdiid radiodont known so far, <i>Titanokorys gainesi</i>, gen. et sp. nov., from the Burgess Shale (Marble Canyon, Kootenay National Park, British Columbia). Estimated to reach half-a-meter in length, this new species bears a very large ovoid-shaped central carapace with distinct short posterolateral processes and an anterior spine. Geometric morphometric analyses highlight the high diversity of carapace shapes in hurdiids and show that <i>Titanokorys</i> bridges a morphological gap between forms with long and short carapaces. Carapace shape, however, is prone to homoplasy and shows no consistent relationship with trophic ecology, as demonstrated by new data, including a reappraisal of the poorly known <i>Pahvantia</i>. Despite distinct carapaces, <i>Titanokorys</i> shares similar rake-like appendages for sediment-sifting with <i>Cambroraster,</i> a smaller but much more abundant sympatric hurdiid from the Burgess Shale<i>.</i> The co-occurrence of these two species on the same bedding planes highlights the potential competition for benthic resources and the high diversity of large predators sustained by Cambrian communities.
DOI: 10.6084/m9.figshare.15155999
title: Table 2.1-3 Caron & Moysiuk.xlsx from A giant nektobenthic radiodont from the Burgess Shale and the significance of hurdiid carapace diversity

description: Radiodonts, stem-group euarthropods that evolved during the Cambrian explosion, were among the largest and most diversified lower palaeozoic predators. These animals were widespread geographically, occupying a variety of ecological niches, from benthic foragers to nektonic suspension feeders and apex predators. Here, we describe the largest Cambrian hurdiid radiodont known so far, <i>Titanokorys gainesi</i>, gen. et sp. nov., from the Burgess Shale (Marble Canyon, Kootenay National Park, British Columbia). Estimated to reach half-a-meter in length, this new species bears a very large ovoid-shaped central carapace with distinct short posterolateral processes and an anterior spine. Geometric morphometric analyses highlight the high diversity of carapace shapes in hurdiids and show that <i>Titanokorys</i> bridges a morphological gap between forms with long and short carapaces. Carapace shape, however, is prone to homoplasy and shows no consistent relationship with trophic ecology, as demonstrated by new data, including a reappraisal of the poorly known <i>Pahvantia</i>. Despite distinct carapaces, <i>Titanokorys</i> shares similar rake-like appendages for sediment-sifting with <i>Cambroraster,</i> a smaller but much more abundant sympatric hurdiid from the Burgess Shale<i>.</i> The co-occurrence of these two species on the same bedding planes highlights the potential competition for benthic resources and the high diversity of large predators sustained by Cambrian communities.
DOI: 10.6084/m9.figshare.15155999.v1
title: Table 2.1-3 Caron & Moysiuk.xlsx from A giant nektobenthic radiodont from the Burgess Shale and the significance of hurdiid carapace diversity

description: Radiodonts, stem-group euarthropods that evolved during the Cambrian explosion, were among the largest and most diversified lower palaeozoic predators. These animals were widespread geographically, occupying a variety of ecological niches, from benthic foragers to nektonic suspension feeders and apex predators. Here, we describe the largest Cambrian hurdiid radiodont known so far, <i>Titanokorys gainesi</i>, gen. et sp. nov., from the Burgess Shale (Marble Canyon, Kootenay National Park, British Columbia). Estimated to reach half-a-meter in length, this new species bears a very large ovoid-shaped central carapace with distinct short posterolateral processes and an anterior spine. Geometric morphometric analyses highlight the high diversity of carapace shapes in hurdiids and show that <i>Titanokorys</i> bridges a morphological gap between forms with long and short carapaces. Carapace shape, however, is prone to homoplasy and shows no consistent relationship with trophic ecology, as demonstrated by new data, including a reappraisal of the poorly known <i>Pahvantia</i>. Despite distinct carapaces, <i>Titanokorys</i> shares similar rake-like appendages for sediment-sifting with <i>Cambroraster,</i> a smaller but much more abundant sympatric hurdiid from the Burgess Shale<i>.</i> The co-occurrence of these two species on the same bedding planes highlights the potential competition for benthic resources and the high diversity of large predators sustained by Cambrian communities.