cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.21755681.v1
title: Profile of pharmaceutical interventions of a pharmacotherapeutic follow-up model for diabetic patients in a community pharmacy

description: Abstract The insertion of Pharmaceutical Care in Primary Health Care (PHC) improves patients’ clinical outcomes and quality of life. Pharmacotherapeutic follow-up can contribute to the management of chronic diseases such as diabetes, promoting better glycemic control and adherence to therapy. This study aimed to assess the Drug-therapy Problems (DTPs) and Pharmacist Interventions (PIs) on the pharmacotherapeutic management in patients with type 2 diabetes mellitus (T2DM) in a community pharmacy. A quantitative, retrospective, and cross-sectional study was conducted in a Pharmaceutical Care Program within the PHC in Juiz de Fora (Minas Gerais, Brazil). Inclusion criteria were patients with T2DM above 18, who attended at least three pharmaceutical consultations between July 2016 and October 2018 and presented two or more glycated hemoglobin tests. The study group (n = 17) was largely composed of women (65%), elderly (76%), sedentary (72%), and obese people (52%). The resolution was achieved in 79% of the DTPs identified (n = 115). Most of DTPs were related to administration and adherence to pharmacotherapy (46%). 60% of the 437 PIs involved the provision of information and counseling. In other words, accessible interventions lead to high resolvability. Therefore, clinical actuation of pharmacists could improve the prognosis in diabetes treatment.
DOI: 10.6084/m9.figshare.14277812
title: Plexiform Lesions in an Experimental Model of Monocrotalin-Induced Pulmonary Arterial Hypertension

description: Abstract Background The monocrotaline (MCT)-induced pulmonary arterial hypertension model is one of the most reproduced today, presenting as a limitation the absence of plexiform lesions, typical manifestations of the severe disease in humans. Objective To evaluate the severity of MCT-induced pulmonary arteriopathy by pathological findings of lung and heart tissue samples, clinical course and 37-day survival. Methods Fifty male Wistar rats were divided into one of the four groups – control (CG) (n = 10) and three intervention (MCT) groups. The MCT groups received intraperitoneal injection (60 mg/kg) of MCT and remained exposed to the substance for 15 days (G15, n = 10), 30 days (G30, n = 10) and 37 days (G37, n = 20). At the end of each period, the animals were sacrificed, and pulmonary and cardiac tissues were collected for anatomopathological and morphometric analysis. The Kruskal-Wallis test was used, considering a level of significance of 5%. Results In the lungs of MCT animals, lesions related to pulmonary arteriopathy were found, including muscularization of the arterioles, hypertrophy of the middle layer and concentric neointimal lesions. Complex lesions were observed in MCT groups, described as plexiform and plexiform-like lesions. Right ventricular hypertrophy was evidenced by increased thickness and diameter of the cardiomyocytes and a significant increase in the right ventricular wall thickness (p &lt;0.0000). Conclusion The MCT model was able to generate moderate-severe pulmonary arteriopathy associated with secondary right ventricular hypertrophy. The 37-day survival rate was 50%. To our knowledge, this study was the first to note the presence of complex vascular lesions, similar to those observed in patients with severe pulmonary arterial hypertension, in an isolated MCT model. (Arq Bras Cardiol. 2020; 115(3):480-490)
DOI: 10.6084/m9.figshare.14277812.v1
title: Plexiform Lesions in an Experimental Model of Monocrotalin-Induced Pulmonary Arterial Hypertension

description: Abstract Background The monocrotaline (MCT)-induced pulmonary arterial hypertension model is one of the most reproduced today, presenting as a limitation the absence of plexiform lesions, typical manifestations of the severe disease in humans. Objective To evaluate the severity of MCT-induced pulmonary arteriopathy by pathological findings of lung and heart tissue samples, clinical course and 37-day survival. Methods Fifty male Wistar rats were divided into one of the four groups – control (CG) (n = 10) and three intervention (MCT) groups. The MCT groups received intraperitoneal injection (60 mg/kg) of MCT and remained exposed to the substance for 15 days (G15, n = 10), 30 days (G30, n = 10) and 37 days (G37, n = 20). At the end of each period, the animals were sacrificed, and pulmonary and cardiac tissues were collected for anatomopathological and morphometric analysis. The Kruskal-Wallis test was used, considering a level of significance of 5%. Results In the lungs of MCT animals, lesions related to pulmonary arteriopathy were found, including muscularization of the arterioles, hypertrophy of the middle layer and concentric neointimal lesions. Complex lesions were observed in MCT groups, described as plexiform and plexiform-like lesions. Right ventricular hypertrophy was evidenced by increased thickness and diameter of the cardiomyocytes and a significant increase in the right ventricular wall thickness (p &lt;0.0000). Conclusion The MCT model was able to generate moderate-severe pulmonary arteriopathy associated with secondary right ventricular hypertrophy. The 37-day survival rate was 50%. To our knowledge, this study was the first to note the presence of complex vascular lesions, similar to those observed in patients with severe pulmonary arterial hypertension, in an isolated MCT model. (Arq Bras Cardiol. 2020; 115(3):480-490)
DOI: 10.6084/m9.figshare.21639955
title: Pricing, strategies, and entrepreneurial decisions: market fit and competition analysis in the case of Sabor Anthigo

description: Abstract This teaching case portrays the reality of a long-lived small company - the Restaurant e Pizzaria Sabor Anthigo. It aimed to contextualize real difficulties presented by an entrepreneur, confronted with sector statistics, environmental, cultural, economic, demographic, and social changes experienced by the enterprise, in line with marketing theories used in classrooms. The data used in the teaching case were collected in two interviews aimed at the entrepreneur and in documents provided by him, in addition to research in establishments in the region and agencies that promote entrepreneurship. It was decided to insert throughout the life and entrepreneurial history of the protagonist, Melquisedec Bahia, practical propositions, doubts, and possible commercial objections experienced by managers and adminisitration students (and related areas), undergraduate or graduate students. The protagonist presents managerial/entrepreneurial anxieties and questions, such as: correctly pricing products and services; segment his target audience; face seasonality; identify the competition; adjust his business. The research question was: can you establish an interesting, viable business fit that communicates value to a certain audience and follows a strategy that provides stability and success for the enterprise? This active methodology encourages the connection between professional challenges and the participant’s reality to develop professional dramatization.
DOI: 10.6084/m9.figshare.21639955.v1
title: Pricing, strategies, and entrepreneurial decisions: market fit and competition analysis in the case of Sabor Anthigo

description: Abstract This teaching case portrays the reality of a long-lived small company - the Restaurant e Pizzaria Sabor Anthigo. It aimed to contextualize real difficulties presented by an entrepreneur, confronted with sector statistics, environmental, cultural, economic, demographic, and social changes experienced by the enterprise, in line with marketing theories used in classrooms. The data used in the teaching case were collected in two interviews aimed at the entrepreneur and in documents provided by him, in addition to research in establishments in the region and agencies that promote entrepreneurship. It was decided to insert throughout the life and entrepreneurial history of the protagonist, Melquisedec Bahia, practical propositions, doubts, and possible commercial objections experienced by managers and adminisitration students (and related areas), undergraduate or graduate students. The protagonist presents managerial/entrepreneurial anxieties and questions, such as: correctly pricing products and services; segment his target audience; face seasonality; identify the competition; adjust his business. The research question was: can you establish an interesting, viable business fit that communicates value to a certain audience and follows a strategy that provides stability and success for the enterprise? This active methodology encourages the connection between professional challenges and the participant’s reality to develop professional dramatization.
DOI: 10.6084/m9.figshare.21755686
title: BRS 429: sweet cassava with yellow pulp and high technological and sensory qualities

description: Abstract BRS 429 is a sweet cassava cultivar with yellow pulp and technological qualities (high root yield, early maturity, and favorable plant architecture) and sensory qualities (short cooking time, little fiber, and soft texture) that make it an excellent option for cultivation in the Distrito Federal, Paraná, and São Paulo, Brazil.
DOI: 10.6084/m9.figshare.21755686.v1
title: BRS 429: sweet cassava with yellow pulp and high technological and sensory qualities

description: Abstract BRS 429 is a sweet cassava cultivar with yellow pulp and technological qualities (high root yield, early maturity, and favorable plant architecture) and sensory qualities (short cooking time, little fiber, and soft texture) that make it an excellent option for cultivation in the Distrito Federal, Paraná, and São Paulo, Brazil.
DOI: 10.6084/m9.figshare.21755687
title: Inheritance of resistance to Fusarium wilt in the carioca grain type common bean

description: Abstract Carioca grains are the most cultivated commercial group of common bean and Fusarium oxysporum f. sp. phaseoli (Fop) is an important disease under field conditions. Genetic resistance is the most effective control strategy. Thus, our objective was to study the inheritance of Fop resistance in the carioca grain type common bean. Lines CNFC 11965 (S) and CVIII 8511 (R) were crossed to obtain F1 and F2 generations and backcrosses, inoculated with the isolate FOP UFV 01, and severity grades used to estimate genetic parameters. Segregation of resistant and susceptible plants in the F2 generations and backcrosses resulted in dominant monogenic inheritance of Fop resistance. The high values of heritability emphasized the probability of success in the selection processes because environmental factors were not significant. The carioca grain line CVIII 8511 is promising, and its Fop resistance gene can be transferred to commercial cultivars of this group using the backcross method.
DOI: 10.6084/m9.figshare.21755687.v1
title: Inheritance of resistance to Fusarium wilt in the carioca grain type common bean

description: Abstract Carioca grains are the most cultivated commercial group of common bean and Fusarium oxysporum f. sp. phaseoli (Fop) is an important disease under field conditions. Genetic resistance is the most effective control strategy. Thus, our objective was to study the inheritance of Fop resistance in the carioca grain type common bean. Lines CNFC 11965 (S) and CVIII 8511 (R) were crossed to obtain F1 and F2 generations and backcrosses, inoculated with the isolate FOP UFV 01, and severity grades used to estimate genetic parameters. Segregation of resistant and susceptible plants in the F2 generations and backcrosses resulted in dominant monogenic inheritance of Fop resistance. The high values of heritability emphasized the probability of success in the selection processes because environmental factors were not significant. The carioca grain line CVIII 8511 is promising, and its Fop resistance gene can be transferred to commercial cultivars of this group using the backcross method.
DOI: 10.6084/m9.figshare.21755696
title: Inflammatory Phenotype by OCT Coronary Imaging: Specific Features Among De Novo Lesions, In-Stent Neointima, and In-Stent Neo-Atherosclerosis

description: Abstract Background Coronary stenosis can be caused de novo atherosclerosis, in-stent restenosis, and in-stent neoatherosclerosis, three entities that develop from a diverse pathophysiological milieu. Objective This study aims to investigate, using optical coherence tomography (OCT), whether or not coronary lesions related to these processes differ in their local inflammatory profile. Methods Retrospective analysis of patients with diagnosed or suspected coronary lesions who had undergone OCT imaging for clinical reasons. Macrophage and intra-plaque neovascularization were assessed by OCT and used as surrogates of local inflammation. A significance level of &lt; 0.05 was adopted as statistically significant. Results From the 121 lesions, 74 were de novo, 29 were restenosis, and 18 were neoatherosclerosis. Neovascularization was found in 65.8% of de novo, 10.3% in restenosis, and 94.4% in neoatherosclerosis (p&lt;0.01 for all). The volume of neovascularization was different among lesion types (950 vs. 0 vs. 6220, respectively [median values in 1000 x µm3/mm]; p&lt;0.01 for all), which were significantly higher in neoatherosclerosis and lower in restenosis. The presence of macrophages differed among the lesions (95.9% in de novo vs. 6.9% in restenosis vs. 100% in neoatherosclerosis [p&lt;0.01 for all]). Moreover, the intensity of macrophagic infiltration was different among lesion types (2.5 vs. 0.0 vs. 4.5, respectively [median values of macrophage score]; p&lt;0.01 for all), significantly higher in neoatheroscleosis and lower in restenosis. Conclusion When compared using coronary OCT, de novo atherosclerosis, in-stent restenosis, and neoatherosclerosis presented markedly different inflammatory phenotypes.
DOI: 10.6084/m9.figshare.21755696.v1
title: Inflammatory Phenotype by OCT Coronary Imaging: Specific Features Among De Novo Lesions, In-Stent Neointima, and In-Stent Neo-Atherosclerosis

description: Abstract Background Coronary stenosis can be caused de novo atherosclerosis, in-stent restenosis, and in-stent neoatherosclerosis, three entities that develop from a diverse pathophysiological milieu. Objective This study aims to investigate, using optical coherence tomography (OCT), whether or not coronary lesions related to these processes differ in their local inflammatory profile. Methods Retrospective analysis of patients with diagnosed or suspected coronary lesions who had undergone OCT imaging for clinical reasons. Macrophage and intra-plaque neovascularization were assessed by OCT and used as surrogates of local inflammation. A significance level of &lt; 0.05 was adopted as statistically significant. Results From the 121 lesions, 74 were de novo, 29 were restenosis, and 18 were neoatherosclerosis. Neovascularization was found in 65.8% of de novo, 10.3% in restenosis, and 94.4% in neoatherosclerosis (p&lt;0.01 for all). The volume of neovascularization was different among lesion types (950 vs. 0 vs. 6220, respectively [median values in 1000 x µm3/mm]; p&lt;0.01 for all), which were significantly higher in neoatherosclerosis and lower in restenosis. The presence of macrophages differed among the lesions (95.9% in de novo vs. 6.9% in restenosis vs. 100% in neoatherosclerosis [p&lt;0.01 for all]). Moreover, the intensity of macrophagic infiltration was different among lesion types (2.5 vs. 0.0 vs. 4.5, respectively [median values of macrophage score]; p&lt;0.01 for all), significantly higher in neoatheroscleosis and lower in restenosis. Conclusion When compared using coronary OCT, de novo atherosclerosis, in-stent restenosis, and neoatherosclerosis presented markedly different inflammatory phenotypes.
DOI: 10.6084/m9.figshare.21755699
title: CHARACTERIZATION OF THE PROFESSIONAL PHYSICAL EDUCATION FIELD IN BRAZILIAN MULTIPROFESSIONAL HEALTH RESIDENCY PROGRAMS

description: ABSTRACT Multiprofessional residencies in the professional health field (MHR) are intersectoral cooperation programs to qualify health professionals. This study aimed to characterize the offer of vacancies meant for the professional Physical Education field in Brazilian MHR programs. It is a descriptive study of a documentary nature on the offer of training vacancies in MHR for the professional Physical Education field in 2022. The characterization of the programs considered: federative unit, proposing institution, total number of general vacancies, vacancies offered for Physical Education, focus of intervention of the programs, and other professional fields presented in the identified programs. A total of 184 vacancies offered by 77 MHR programs that include Physical Education in Brazil were identified. The Northeast region had the highest number of programs (n=29) and vacancies offered (n=89). Family Health was the major focus as to vacancies, while nursing appeared as the most frequent professional field among the identified programs (97.4%). This research work presented the characterization of the offer of vacancies intended for Physical Education in Brazilian MHR programs. Additionally, it evidences the need for a more equitable distribution of vacancies for Physical Education in the country.
DOI: 10.6084/m9.figshare.21755699.v1
title: CHARACTERIZATION OF THE PROFESSIONAL PHYSICAL EDUCATION FIELD IN BRAZILIAN MULTIPROFESSIONAL HEALTH RESIDENCY PROGRAMS

description: ABSTRACT Multiprofessional residencies in the professional health field (MHR) are intersectoral cooperation programs to qualify health professionals. This study aimed to characterize the offer of vacancies meant for the professional Physical Education field in Brazilian MHR programs. It is a descriptive study of a documentary nature on the offer of training vacancies in MHR for the professional Physical Education field in 2022. The characterization of the programs considered: federative unit, proposing institution, total number of general vacancies, vacancies offered for Physical Education, focus of intervention of the programs, and other professional fields presented in the identified programs. A total of 184 vacancies offered by 77 MHR programs that include Physical Education in Brazil were identified. The Northeast region had the highest number of programs (n=29) and vacancies offered (n=89). Family Health was the major focus as to vacancies, while nursing appeared as the most frequent professional field among the identified programs (97.4%). This research work presented the characterization of the offer of vacancies intended for Physical Education in Brazilian MHR programs. Additionally, it evidences the need for a more equitable distribution of vacancies for Physical Education in the country.
DOI: 10.6084/m9.figshare.21639893
title: Humility in organizations: a bibliometric study

description: Abstract Humility is a characteristic little studied in the organizational environment. The interest in research on humility started to gain some representativeness this century. However, literature reviews on humility in management are rare, making it necessary to systematize the relevant knowledge in this field. This research highlights the intellectual structure of the domain, the current studies, and research opportunities associated with humility in organizations. A bibliometric study was carried out from 2000 to 2020, and activity and relationship indicators, such as co-citations and bibliographic coupling, were analyzed. Results show three major thematic lines that make up the intellectual structure of the field: (i) concepts, antecedents, and organizational attributes, (i) methods and scales, and (iii) behavioral issues. This research is organized on four major fronts: (i) expressed humility, (ii) humility and CEOs, (iii) humility and teams, and (iv) humility and organizational behavior. Finally, an agenda for future research is presented, emphasizing the analysis of how expressed humility and humble behavior can be taught and internalized in the organizational culture.
DOI: 10.6084/m9.figshare.21639893.v1
title: Humility in organizations: a bibliometric study

description: Abstract Humility is a characteristic little studied in the organizational environment. The interest in research on humility started to gain some representativeness this century. However, literature reviews on humility in management are rare, making it necessary to systematize the relevant knowledge in this field. This research highlights the intellectual structure of the domain, the current studies, and research opportunities associated with humility in organizations. A bibliometric study was carried out from 2000 to 2020, and activity and relationship indicators, such as co-citations and bibliographic coupling, were analyzed. Results show three major thematic lines that make up the intellectual structure of the field: (i) concepts, antecedents, and organizational attributes, (i) methods and scales, and (iii) behavioral issues. This research is organized on four major fronts: (i) expressed humility, (ii) humility and CEOs, (iii) humility and teams, and (iv) humility and organizational behavior. Finally, an agenda for future research is presented, emphasizing the analysis of how expressed humility and humble behavior can be taught and internalized in the organizational culture.
DOI: 10.6084/m9.figshare.21639889
title: Knowledge connections for conservation of the Atlantic Goliath Grouper, Epinephelus itajara: records of tropical Brazilian coast

description: Abstract The Atlantic Goliath Grouper (AGG), Epinephelus itajara, the largest Epinephelidae in the Atlantic Ocean, it is classified as critically endangered in Brazil. In the Brazilian northeast, studies focusing on the species are still incipient. Here we study the occurrence, habitat use, and spatial distribution of AGG in Alagoas (Brazil) by combining participatory methods, such as Citizen Science and Local Ecological Knowledge. Living individuals represented 64% (n = 85) of the records, while dead individuals were 36% (n = 47), with 14 records from illegal captures. Juveniles are common in estuaries and shallow natural coastal reefs, while adults are distributed in deeper areas on natural and artificial reefs. The occurrence was significantly higher on Alagoas’ southern coast. The São Francisco River (SFR) estuary stood out with 52 occurrences. We mapped 37 occurrence sites for AGG distributed along the coast, emphasising an artificial reef near SFR that received 12 reports about aggregations. The influence area of the SFR was indicated as a priority for species conservation due to the identification of a nursery and possible aggregations close to its mouth. We highlight the urgency of implementing short and long-term management actions along Alagoas’ coast.