DOI: 10.5281/zenodo.7412771
title: Corticolimbic Response to Threat and Recollected Ages of Exposure to Childhood Maltreatment

description: Data files indicating regional BOLD fMRI response of young adults to negative (angry or fearful) faces versus neutral faces in Hariri amygdala activation face matching task. MACE_scores_BOLD_fMRI_amyg_hipp.csv - Contains overall BOLD fMRI response to negative minus neutral faces in bilateral amygdala, hippocampus, fusiform gyrus, inferior frontal gyrus pars triangularis, ventromedial prefrontal cortex, dorsomedial prefrontal cortex and anterior cingulate cortex as well as Maltreatment and Abuse Chronology of Exposure scores for severity of exposure to 10 types of childhood maltreatment across each age of childhood and parameters for age, sex, parental education and childhood financial sufficiency. Early_vs_late_maltreatment_BOLD_fMRI_amyg_hipp_pfc_fusiform_for_mixed_model.xlsx - Data in long format indicating for each participant baseline adjusted BOLD fMRI response to negative minus neutral faces at each TR interval for amygdala, hippocampus, fusiform gyrus, inferior frontal gyrus pars triangularis, ventromedial prefrontal cortex, dorsomedial prefrontal cortex and anterior cingulate cortex with participants classified as having experienced no maltreatment, only early childhood maltreatment on only late childhood maltreatment based on type / time predictors for each region. Early_vs_late_maltreatment_regional_fMRI_response_negative_vs_neutral_faces.xlsx - Individual participant baseline adjusted data for response to negative faces and neutral faces at each TR interval for amygdala, hippocampus, fusiform gyrus, inferior frontal gyrus pars triangularis, ventromedial prefrontal cortex, dorsomedial prefrontal cortex and anterior cingulate cortex with each participant classified as having experienced no maltreatment, only early childhood maltreatment or only late childhood maltreatment based on region specific definitions. Early_vs_late_maltreatment_time_course_BOLD_fMRI_regional_response.xlsx - Group means and sem for baseline adjusted BOLD fMRI response to negative minus neutral faces at each TR interval for amygdala, hippocampus, fusiform gyrus, inferior frontal gyrus pars triangularis, ventromedial prefrontal cortex, dorsomedial prefrontal cortex and anterior cingulate cortex based on region specific groupings classifications as having experienced no maltreatment, only early childhood maltreatment on only late childhood maltreatment. Early_vs_late_maltreatment_time_course_regional_response_negative_vs_neutral_faces.xlsx - Group means and sem for baseline adjusted BOLD fMRI response to negative faces and neutral faces at each TR interval for amygdala, hippocampus, fusiform gyrus, inferior frontal gyrus pars triangularis, ventromedial prefrontal cortex, dorsomedial prefrontal cortex and anterior cingulate cortex based on region specific groupings classifications as having experienced no maltreatment, only early childhood maltreatment on only late childhood maltreatment.
description: Funding for data collection and sensitive period analyses. U.S. National Institutes of Health grant RO1 MH091391; US National Institutes of Health grant RO3 MH113077 to MHT.