cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.9547298
title: Public survey on priorities and preferences in developing locally driven sea level rise plans in eastern coastal states in December 2017

description: This data set contains the responses of 503 persons affiliated with coastal communities in the East Coast of the United States. There is no personally identifiable information contained within this data set. There are 26 questions in the survey, including the consent form, 15 questions about priorities and preferences in developing community-based sea level rise plans, and 10 demographic questions (7 asked in the survey and 3 provided by the survey company). Topics include priorities for inclusion in a plan, methods to fund a plan and subsequent action, and methods to resolve conflict around sea level rise planning. In addition to the results, the full details of the questions are included.
DOI: 10.6084/m9.figshare.9547475.v1
title: Libro Maestro

description: Hoja de Excel para compilar y organizar referencias bibliográficas con menciones a productos de investigación. Material de apoyo para elaborar informes de citación, elaborado por Enrique Rodríguez-Trujano
DOI: 10.6084/m9.figshare.9547154
title: Taiwan_Pteridophyte_Checklist_v.5.9_official.xlsx

description: The full and official version of TPG (2019)-Taiwanese Pteridophyte Checklist. Other details can be seen in TPG (2019) Updating Taiwanese pteridophyte checklist: a new phylogenetic classification. Taiwania 64(4). DOI: 10.6165/tai.2019.64.
DOI: 10.6084/m9.figshare.9547154.v1
title: Taiwan_Pteridophyte_Checklist_v.5.9_official.xlsx

description: The full and official version of TPG (2019)-Taiwanese Pteridophyte Checklist. Other details can be seen in TPG (2019) Updating Taiwanese pteridophyte checklist: a new phylogenetic classification. Taiwania 64(4). DOI: 10.6165/tai.2019.64.
DOI: 10.6084/m9.figshare.9547298.v1
title: Public survey on priorities and preferences in developing locally driven sea level rise plans in eastern coastal states in December 2017

description: This data set contains the responses of 503 persons affiliated with coastal communities in the East Coast of the United States. There is no personally identifiable information contained within this data set. There are 26 questions in the survey, including the consent form, 15 questions about priorities and preferences in developing community-based sea level rise plans, and 10 demographic questions (7 asked in the survey and 3 provided by the survey company). Topics include priorities for inclusion in a plan, methods to fund a plan and subsequent action, and methods to resolve conflict around sea level rise planning. In addition to the results, the full details of the questions are included.
DOI: 10.6084/m9.figshare.9546731
title: Data from: Spatial organisation of expanding bacterial colonies is affected by contact-dependent growth inhibition

description: Data used to produce figures presented in Spatial organisation of expanding bacterial colonies is affected by contact-dependent growth inhibition. For description of each file see data_description.txt
DOI: 10.6084/m9.figshare.9546731.v1
title: Data from: Spatial organisation of expanding bacterial colonies is affected by contact-dependent growth inhibition

description: Data used to produce figures presented in Spatial organisation of expanding bacterial colonies is affected by contact-dependent growth inhibition. For description of each file see data_description.txt
DOI: 10.6084/m9.figshare.9545174
title: Family-Wise Error Rate Controlling Procedures for Discrete Data

description: In applications such as clinical safety analysis, the data of the experiments usually consist of frequency counts. In the analysis of such data, researchers often face the problem of multiple testing based on discrete test statistics, aimed at controlling family-wise error rate (FWER). Most existing FWER controlling procedures are developed for continuous data, which are often conservative when analyzing discrete data. By using minimal attainable <i>p</i>-values, several FWER controlling procedures have been specifically developed for discrete data in the literature. In this article, by using known marginal distributions of true null <i>p</i>-values, three more powerful stepwise procedures are developed, which are modified versions of the conventional Bonferroni, Holm and Hochberg procedures, respectively. It is shown that the first two procedures strongly control the FWER under arbitrary dependence and are more powerful than the existing Tarone-type procedures, while the last one only ensures control of the FWER in special settings. Through extensive simulation studies, we provide numerical evidence of superior performance of the proposed procedures in terms of the FWER control and minimal power. A real clinical safety data are used to demonstrate applications of our proposed procedures. An R package “MHTdiscrete” and a web application are developed for implementing the proposed procedures.
DOI: 10.6084/m9.figshare.9545174.v2
title: Family-Wise Error Rate Controlling Procedures for Discrete Data

description: In applications such as clinical safety analysis, the data of the experiments usually consist of frequency counts. In the analysis of such data, researchers often face the problem of multiple testing based on discrete test statistics, aimed at controlling family-wise error rate (FWER). Most existing FWER controlling procedures are developed for continuous data, which are often conservative when analyzing discrete data. By using minimal attainable <i>p</i>-values, several FWER controlling procedures have been specifically developed for discrete data in the literature. In this article, by using known marginal distributions of true null <i>p</i>-values, three more powerful stepwise procedures are developed, which are modified versions of the conventional Bonferroni, Holm and Hochberg procedures, respectively. It is shown that the first two procedures strongly control the FWER under arbitrary dependence and are more powerful than the existing Tarone-type procedures, while the last one only ensures control of the FWER in special settings. Through extensive simulation studies, we provide numerical evidence of superior performance of the proposed procedures in terms of the FWER control and minimal power. A real clinical safety data are used to demonstrate applications of our proposed procedures. An R package “MHTdiscrete” and a web application are developed for implementing the proposed procedures.
DOI: 10.6084/m9.figshare.9545174.v1
title: Familywise Error Rate Controlling Procedures for Discrete Data

description: In applications such as clinical safety analysis, the data of the experiments usually consists of frequency counts. In the analysis of such data, researchers often face the problem of multiple testing based on discrete test statistics, aimed at controlling family-wise error rate (FWER). Most existing FWER controlling procedures are developed for continuous data, which are often conservative when analyzing discrete data. By using minimal attainable <i>p</i>-values, several FWER controlling procedures have been specifically developed for discrete data in the literature. In this paper, by utilizing known marginal distributions of true null <i>p</i>-values, three more powerful stepwise procedures are developed, which are modified versions of the conventional Bonferroni, Holm and Hochberg procedures, respectively. It is shown that the first two procedures strongly control the FWER under arbitrary dependence and are more powerful than the existing Tarone-type procedures, while the last one only ensures control of the FWER in special settings. Through extensive simulation studies, we provide numerical evidence of superior performance of the proposed procedures in terms of the FWER control and minimal power. A real clinical safety data is used to demonstrate applications of our proposed procedures. An R package “MHTdiscrete” and a web application are developed for implementing the proposed procedures.
DOI: 10.6084/m9.figshare.9544061
title: 2019_Synthetic_lethal_interaction_of_SHOC2_depletion_with_MEK_inhibition_in_RAS_driven_cancers

description: This dataset contains supporting data for "Synthetic lethal interaction of SHOC2 depletion with MEK inhibition in RAS-driven cancers", Cell Reports (2019).<br>Contents:<br>genomewide.chip: Alignment file for the three screens performed with the Avana CRISPR library<br>Files beginning with genomewide_scores: raw sequencing readcounts for the three cell lines screened with the Avana CRISPR library. Column headers indicate early or late time point and treatment condition (DMSO or trametinib). There are multiple sequencing replicates for each cell line in separate files.<br>minipool.chip: Alignment file for the seven screens performed with the reduced representation CRISPR library.<br>Files beginning with minipool_scores: raw sequencing readcounts for the three cell lines screened with the Avana CRISPR library. Column headers indicate early or late time point and treatment condition (DMSO or trametinib). A pDNA reference is also provided.
DOI: 10.6084/m9.figshare.9544061.v1
title: 2019_Synthetic_lethal_interaction_of_SHOC2_depletion_with_MEK_inhibition_in_RAS_driven_cancers

description: This dataset contains supporting data for "Synthetic lethal interaction of SHOC2 depletion with MEK inhibition in RAS-driven cancers", Cell Reports (2019).<br>Contents:<br>genomewide.chip: Alignment file for the three screens performed with the Avana CRISPR library<br>Files beginning with genomewide_scores: raw sequencing readcounts for the three cell lines screened with the Avana CRISPR library. Column headers indicate early or late time point and treatment condition (DMSO or trametinib). There are multiple sequencing replicates for each cell line in separate files.<br>minipool.chip: Alignment file for the seven screens performed with the reduced representation CRISPR library.<br>Files beginning with minipool_scores: raw sequencing readcounts for the three cell lines screened with the Avana CRISPR library. Column headers indicate early or late time point and treatment condition (DMSO or trametinib). A pDNA reference is also provided.
DOI: 10.25375/uct.9541991
title: Khayelitsha Hospital TB study pharmacokinetic variables: Non compartmental analysis

description: Human immunodeficiency virus associated tuberculosis (HIV-TB) comprise 10% of global tuberculosis cases but contribute a disproportionate 22% of global tuberculosis mortality. HIV-infected patients hospitalized with HIV-TB have high high case fatality rates despite treatment and often present with a clinical picture compatible with sepsis. There is paucity of data in critically ill HIV-infected patients admitted to hospital at the time of tuberculosis diagnosis. Improved, evidence-based treatment interventions in this patient group are urgently needed to improve survival.We performed intensive pharmacokinetic studies (from 0-8 hours) in a high burden setting (Khayelitsha Hospital, Cape Town), within the routine service. We assessed rifampicin, isoniazid and pyrazinamide exposure in a group of hospitalized HIV-TB patients and a group of outpatients on the third day of standard antituberculosis therapy using non-compartmental analysis. We followed hospitalized patients for 12 weeks to asses survival. We compared pharmacokinetic exposures in hospitalized patients and outpatients; hospitalized patients who survived twelve weeks and those who died; and hospitalized patients presenting with high lactate (more than 2.2 mmol/L) and patient presenting with normal lactate.
DOI: 10.25375/uct.9541991.v1
title: Khayelitsha Hospital TB study pharmacokinetic variables: Non compartmental analysis

description: Human immunodeficiency virus associated tuberculosis (HIV-TB) comprise 10% of global tuberculosis cases but contribute a disproportionate 22% of global tuberculosis mortality. HIV-infected patients hospitalized with HIV-TB have high high case fatality rates despite treatment and often present with a clinical picture compatible with sepsis. There is paucity of data in critically ill HIV-infected patients admitted to hospital at the time of tuberculosis diagnosis. Improved, evidence-based treatment interventions in this patient group are urgently needed to improve survival.We performed intensive pharmacokinetic studies (from 0-8 hours) in a high burden setting (Khayelitsha Hospital, Cape Town), within the routine service. We assessed rifampicin, isoniazid and pyrazinamide exposure in a group of hospitalized HIV-TB patients and a group of outpatients on the third day of standard antituberculosis therapy using non-compartmental analysis. We followed hospitalized patients for 12 weeks to asses survival. We compared pharmacokinetic exposures in hospitalized patients and outpatients; hospitalized patients who survived twelve weeks and those who died; and hospitalized patients presenting with high lactate (more than 2.2 mmol/L) and patient presenting with normal lactate.
DOI: 10.6084/m9.figshare.9533537
title: Does faecal matter reflect location? An initial assessment of isotopic variability between consumed prey remains and faecal matter for wild jaguars<sup>*</sup>

description: Faecal isotopic analysis may complement other non-invasive wildlife survey tools for monitoring landscape use by carnivores, such as motion-detecting cameras and non-invasive genetic sampling. We analysed carbon, nitrogen, and strontium isotopes in faecal matter produced by jaguars (<i>Panthera onca</i>) as well as bones from consumed prey at the Mountain Pine Ridge Forest Reserve (MPR) in Belize, Central America. The MPR is ideally suited for a spatial isotope study as vegetation and geology both vary considerably. The isotopic composition of faecal matter should reflect the habitat and geology where consumed prey lived. We used bone from consumed prey recovered from jaguar scats as a proxy for diet. Faecal matter and bone showed comparable spatial isotopic trends, suggesting that the isotopic composition of jaguar faeces can be used to detect foraging in different habitats (pine forest versus broadleaf forest) or on different geologies (Mesozoic carbonates; Palaeozoic granite, contact metamorphics, and metasediments). This result is reassuring as bones are not always present in carnivore scats. Studying landscape use by cryptic and wide-ranging carnivore species like jaguars remains challenging. Isotopic analysis of faecal matter complements the existing array of non-invasive spatial monitoring tools.
DOI: 10.6084/m9.figshare.9533510
title: Longer analgesic effect with naproxen sodium than ibuprofen in post-surgical dental pain: a randomized, double-blind, placebo-controlled, single-dose trial

description: <b>Background:</b> Non-steroidal anti-inflammatory drugs (NSAIDs) are recommended as first-line medications in mild-to-moderate acute pain. However, comparative data regarding the duration of analgesia for commonly-used NSAIDs at non-prescription doses is lacking. This study evaluated the time to rescue medication following a single dose of naproxen sodium (NAPSO) vs ibuprofen (IBU) and placebo in subjects with moderate-to-severe post-surgical dental pain. <b>Methods:</b> This single-center, randomized, double-blind, parallel group, placebo-controlled study included healthy subjects with moderate-to-severe baseline pain (Categorical Pain Intensity Scale) who also rated their pain ≥ 5 on a 0–10 pain intensity Numerical Rating Scale following extraction of two impacted mandibular third molars. A single oral dose of NAPSO (440 mg), IBU (400 mg), or placebo was administered. The primary efficacy endpoint was the time to first rescue medication, while secondary endpoints included the sum of pain intensity difference (SPID) and total pain relief (TOTPAR) over 24 h. ClinicalTrials.gov trial registration number: NCT03404206 (EudraCT 2017-005049-67). <b>Results:</b> In the per protocol population (<i>n</i> = 385; mean age = 19 years), the time to rescue medication was significantly (<i>p</i> <b>Conclusions:</b> The duration of pain relief after a single dose of NAPSO was significantly longer than after IBU, and significantly fewer NAPSO-treated subjects required rescue medication over a 24-h period. <b>Trial registration:</b>ClinicalTrials.gov identifier: NCT03404206.
DOI: 10.6084/m9.figshare.9533537.v1
title: Does faecal matter reflect location? An initial assessment of isotopic variability between consumed prey remains and faecal matter for wild jaguars<sup>*</sup>

description: Faecal isotopic analysis may complement other non-invasive wildlife survey tools for monitoring landscape use by carnivores, such as motion-detecting cameras and non-invasive genetic sampling. We analysed carbon, nitrogen, and strontium isotopes in faecal matter produced by jaguars (<i>Panthera onca</i>) as well as bones from consumed prey at the Mountain Pine Ridge Forest Reserve (MPR) in Belize, Central America. The MPR is ideally suited for a spatial isotope study as vegetation and geology both vary considerably. The isotopic composition of faecal matter should reflect the habitat and geology where consumed prey lived. We used bone from consumed prey recovered from jaguar scats as a proxy for diet. Faecal matter and bone showed comparable spatial isotopic trends, suggesting that the isotopic composition of jaguar faeces can be used to detect foraging in different habitats (pine forest versus broadleaf forest) or on different geologies (Mesozoic carbonates; Palaeozoic granite, contact metamorphics, and metasediments). This result is reassuring as bones are not always present in carnivore scats. Studying landscape use by cryptic and wide-ranging carnivore species like jaguars remains challenging. Isotopic analysis of faecal matter complements the existing array of non-invasive spatial monitoring tools.
DOI: 10.6084/m9.figshare.9527900
title: Data for paper of Guangdong's Energy Intensity.xlsx

description: The data is about energy intensity, per capita GDP, FDI, Urbanization, Industrial Structure, Tech and spatial weigth of Guangdong Province in China from 2005 to 2016.
DOI: 10.6084/m9.figshare.9533510.v2
title: Longer analgesic effect with naproxen sodium than ibuprofen in post-surgical dental pain: a randomized, double-blind, placebo-controlled, single-dose trial

description: <b>Background:</b> Non-steroidal anti-inflammatory drugs (NSAIDs) are recommended as first-line medications in mild-to-moderate acute pain. However, comparative data regarding the duration of analgesia for commonly-used NSAIDs at non-prescription doses is lacking. This study evaluated the time to rescue medication following a single dose of naproxen sodium (NAPSO) vs ibuprofen (IBU) and placebo in subjects with moderate-to-severe post-surgical dental pain. <b>Methods:</b> This single-center, randomized, double-blind, parallel group, placebo-controlled study included healthy subjects with moderate-to-severe baseline pain (Categorical Pain Intensity Scale) who also rated their pain ≥ 5 on a 0–10 pain intensity Numerical Rating Scale following extraction of two impacted mandibular third molars. A single oral dose of NAPSO (440 mg), IBU (400 mg), or placebo was administered. The primary efficacy endpoint was the time to first rescue medication, while secondary endpoints included the sum of pain intensity difference (SPID) and total pain relief (TOTPAR) over 24 h. ClinicalTrials.gov trial registration number: NCT03404206 (EudraCT 2017-005049-67). <b>Results:</b> In the per protocol population (<i>n</i> = 385; mean age = 19 years), the time to rescue medication was significantly (<i>p</i> <b>Conclusions:</b> The duration of pain relief after a single dose of NAPSO was significantly longer than after IBU, and significantly fewer NAPSO-treated subjects required rescue medication over a 24-h period. <b>Trial registration:</b>ClinicalTrials.gov identifier: NCT03404206.
DOI: 10.6084/m9.figshare.9533510.v1
title: Longer analgesic effect with naproxen sodium than ibuprofen in postsurgical dental pain: a randomized, double-blind, placebo-controlled, single-dose trial

description: <b>Background.</b> Non-steroidal anti-inflammatory drugs (NSAIDs) are recommended as first-line medications in mild-to-moderate acute pain. However, comparative data regarding the duration of analgesia for commonly-used NSAIDs at non-prescription doses is lacking. We evaluated the time to rescue medication following a single dose of naproxen sodium (NAPSO) versus ibuprofen (IBU) and placebo in subjects with moderate-to-severe postsurgical dental pain. <b>Methods.</b> Our single-center, randomized, double-blind, parallel group, placebo-controlled study included healthy subjects with moderate-to-severe baseline pain (Categorical Pain Intensity Scale) who also rated their pain ≥5 on a 0-10 pain intensity Numerical Rating Scale following extraction of two impacted mandibular third molars. A single oral dose of NAPSO (440 mg), IBU (400 mg), or placebo was administered. The primary efficacy endpoint was the time to first rescue medication, while secondary endpoints included the sum of pain intensity difference (SPID) and total pain relief (TOTPAR) over 24 h. ClinicalTrials.gov trial registration number: NCT03404206 (EudraCT 2017-005049-67). <b>Results.</b> In the per protocol population (n = 385; mean age 19 years), the time to rescue medication was significantly (p <b>Conclusions.</b> The duration of pain relief after a single dose of NAPSO was significantly longer than after IBU, and significantly fewer NAPSO-treated subjects required rescue medication over a 24-h period.
DOI: 10.6084/m9.figshare.9518603
title: A Lagrangian drifter for surveys of water surface roughness in streams

description: Water surface roughness in rivers and streams is mainly driven by flow, turbulence and riverbed conditions. Conversely, water surface roughness gives easy access to information about hydrodynamics – provided that measurements are possible at sufficient spatial-temporal resolution and accuracy. We present a novel small-size (diameter 28 mm) drifter, which detects water surface roughness through acceleration measurements while floating on the water surface. Laboratory tests revealed a good agreement between drifter-based measurements and optical characterization of surface roughness. Only very short waves with periods &lt;0.15 s remained undetected by the drifter. Results from laboratory and field experiments show strong correlations between the drifter-measured water surface roughness, flow and shear velocities, Froude and Reynolds numbers. The small-sized drifter is particularly appropriate for reach-scale measurements in streams, where the application of other devices or methods is too large or laborious.
DOI: 10.6084/m9.figshare.9518603.v1
title: A Lagrangian drifter for surveys of water surface roughness in streams

description: Water surface roughness in rivers and streams is mainly driven by flow, turbulence and riverbed conditions. Conversely, water surface roughness gives easy access to information about hydrodynamics – provided that measurements are possible at sufficient spatial-temporal resolution and accuracy. We present a novel small-size (diameter 28 mm) drifter, which detects water surface roughness through acceleration measurements while floating on the water surface. Laboratory tests revealed a good agreement between drifter-based measurements and optical characterization of surface roughness. Only very short waves with periods &lt;0.15 s remained undetected by the drifter. Results from laboratory and field experiments show strong correlations between the drifter-measured water surface roughness, flow and shear velocities, Froude and Reynolds numbers. The small-sized drifter is particularly appropriate for reach-scale measurements in streams, where the application of other devices or methods is too large or laborious.
DOI: 10.6084/m9.figshare.9516491
title: Carter collar data.xlsx

description: pressure and area testing of a range of different collar types subjected to 3 different forces
DOI: 10.6084/m9.figshare.9516491.v1
title: Carter collar data.xlsx

description: pressure and area testing of a range of different collar types subjected to 3 different forces