cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.5862000
title: ANALYSIS OF THE PREVALENCE OF BURNOUT SYNDROME IN PROFESSIONALS OF PRIMARY HEALTH CARE

description: Abstract Burnout syndrome results from a chronic process of exposure to labor stressors. It is characterized by emotional exhaustion dimensions, depersonalization and low personal accomplishment. Health professionals are prone to it by dealing directly with people and suffering, which harms their health and the care offered to society. The primary health care is the level of care that is most adjacent to the community, exposing professionals to their realities. This study aims to identify the prevalence of burnout in Primary Care professionals and associated factors. This is a cross-sectional study carried out with 153 health care professionals from the city of Juiz de Fora, Minas Gerais, Brazil, between 2013 and 2014. The Maslach Burnout Inventory was used to measure the outcome. The prevalence of the syndrome was 51%, highlighting that the prevalence was higher among nursing professionals. The variables associated with the outcome after multivariate analysis were: self-assessment of poor health status and job dissatisfaction. Work at the primary level of care is complex and demanding, which makes it relevant to care for the health and satisfaction of these professionals, in order to protect their well-being and the production of quality care for society.
DOI: 10.6084/m9.figshare.5862000.v1
title: ANALYSIS OF THE PREVALENCE OF BURNOUT SYNDROME IN PROFESSIONALS OF PRIMARY HEALTH CARE

description: Abstract Burnout syndrome results from a chronic process of exposure to labor stressors. It is characterized by emotional exhaustion dimensions, depersonalization and low personal accomplishment. Health professionals are prone to it by dealing directly with people and suffering, which harms their health and the care offered to society. The primary health care is the level of care that is most adjacent to the community, exposing professionals to their realities. This study aims to identify the prevalence of burnout in Primary Care professionals and associated factors. This is a cross-sectional study carried out with 153 health care professionals from the city of Juiz de Fora, Minas Gerais, Brazil, between 2013 and 2014. The Maslach Burnout Inventory was used to measure the outcome. The prevalence of the syndrome was 51%, highlighting that the prevalence was higher among nursing professionals. The variables associated with the outcome after multivariate analysis were: self-assessment of poor health status and job dissatisfaction. Work at the primary level of care is complex and demanding, which makes it relevant to care for the health and satisfaction of these professionals, in order to protect their well-being and the production of quality care for society.
DOI: 10.6084/m9.figshare.5861991
title: In vitro evaluation of the anti-leishmanial activity and toxicity of PK11195

description: BACKGROUND Leishmaniasis, one of the most neglected diseases, is a serious public health problem in many countries, including Brazil. Currently available treatments require long-term use and have serious side effects, necessitating the development of new therapeutic interventions. Because translocator protein (TSPO) levels are reduced in Leishmania amazonensis-infected cells and because this protein participates in apoptosis and immunomodulation, TSPO represents a potential target for Leishmania chemotherapy. The present study evaluated PK11195, a ligand of this protein, as an anti-leishmanial agent. OBJECTIVE To evaluate the leishmanicidal activity of PK11195 against L. amazonensis in infected CBA mouse macrophages in vitro. METHODS The viability of axenic L. amazonensis, Leishmania major, and Leishmania braziliensis promastigotes was assessed after 48 h treatment with PK11195 (0.2-400 µM). Additionally, intracellular parasite viability was evaluated to determine IC50 values and the number of viable parasites in infected macrophages treated with PK11195 (50-100 µM). Infected macrophages were then treated with PK11195 (25-100 µM) to determine the percentage of L. amazonensis-infected cells and the number of parasites per infected cell. Electron microscopy was used to investigate morphological changes caused by PK11195. The production of free oxygen radicals, nitric oxide, and pro-inflammatory cytokines was also evaluated in infected macrophages treated with PK11195 and primed or not primed with IFN-γ. FINDINGS Median IC50 values for PK11195 were 14.2 µM for L. amazonensis, 8.2 µM for L. major, and 3.5 µM for L. braziliensis. The selective index value for L. amazonensis was 13.7, indicating the safety of PK11195 for future testing in mammals. Time- and dose-dependent reductions in the percentage of infected macrophages, the number of parasites per infected macrophage, and the number of viable intracellular parasites were observed. Electron microscopy revealed some morphological alterations suggestive of autophagy. Interestingly, MCP-1 and superoxide levels were reduced in L. amazonensis-infected macrophages treated with PK11195. MAIN CONCLUSIONS PK11195 causes the killing of amastigotes in vitro by mechanisms independent of inflammatory mediators and causes morphological alterations within Leishmania parasites, suggestive of autophagy, at doses that are non-toxic to macrophages. Thus, this molecule has demonstrated potential as an anti-leishmanial agent.
DOI: 10.6084/m9.figshare.5861991.v1
title: In vitro evaluation of the anti-leishmanial activity and toxicity of PK11195

description: BACKGROUND Leishmaniasis, one of the most neglected diseases, is a serious public health problem in many countries, including Brazil. Currently available treatments require long-term use and have serious side effects, necessitating the development of new therapeutic interventions. Because translocator protein (TSPO) levels are reduced in Leishmania amazonensis-infected cells and because this protein participates in apoptosis and immunomodulation, TSPO represents a potential target for Leishmania chemotherapy. The present study evaluated PK11195, a ligand of this protein, as an anti-leishmanial agent. OBJECTIVE To evaluate the leishmanicidal activity of PK11195 against L. amazonensis in infected CBA mouse macrophages in vitro. METHODS The viability of axenic L. amazonensis, Leishmania major, and Leishmania braziliensis promastigotes was assessed after 48 h treatment with PK11195 (0.2-400 µM). Additionally, intracellular parasite viability was evaluated to determine IC50 values and the number of viable parasites in infected macrophages treated with PK11195 (50-100 µM). Infected macrophages were then treated with PK11195 (25-100 µM) to determine the percentage of L. amazonensis-infected cells and the number of parasites per infected cell. Electron microscopy was used to investigate morphological changes caused by PK11195. The production of free oxygen radicals, nitric oxide, and pro-inflammatory cytokines was also evaluated in infected macrophages treated with PK11195 and primed or not primed with IFN-γ. FINDINGS Median IC50 values for PK11195 were 14.2 µM for L. amazonensis, 8.2 µM for L. major, and 3.5 µM for L. braziliensis. The selective index value for L. amazonensis was 13.7, indicating the safety of PK11195 for future testing in mammals. Time- and dose-dependent reductions in the percentage of infected macrophages, the number of parasites per infected macrophage, and the number of viable intracellular parasites were observed. Electron microscopy revealed some morphological alterations suggestive of autophagy. Interestingly, MCP-1 and superoxide levels were reduced in L. amazonensis-infected macrophages treated with PK11195. MAIN CONCLUSIONS PK11195 causes the killing of amastigotes in vitro by mechanisms independent of inflammatory mediators and causes morphological alterations within Leishmania parasites, suggestive of autophagy, at doses that are non-toxic to macrophages. Thus, this molecule has demonstrated potential as an anti-leishmanial agent.
DOI: 10.6084/m9.figshare.5861988
title: Performance of different methods for reference evapotranspiration estimation in Jaíba, Brazil

description: ABSTRACT FAO Penman-Monteith (FO-PM) is considered the standard method for the estimation of reference evapotranspiration (ET0) but requires various meteorological data, which are often not available. The objective of this work was to evaluate the performance of the FAO-PM method with limited meteorological data and other methods as alternatives to estimate ET0 in Jaíba-MG. The study used daily meteorological data from 2007 to 2016 of the National Institute of Meteorology’s station. Daily ET0 values were randomized, and 70% of these were used to determine the calibration parameters of the ET0 for the equations of each method under study. The remaining data were used to test the calibration against the standard method. Performance evaluation was based on Willmott’s index of agreement, confidence coefficient and root-mean-square error. When one meteorological variable was missing, either solar radiation, relative air humidity or wind speed, or in the simultaneous absence of wind speed and relative air humidity, the FAO-PM method showed the best performances and, therefore, was recommended for Jaíba. The FAO-PM method with two missing variables, one of them being solar radiation, showed intermediate performance. Methods that used only air temperature data are not recommended for the region.
DOI: 10.6084/m9.figshare.5861988.v1
title: Performance of different methods for reference evapotranspiration estimation in Jaíba, Brazil

description: ABSTRACT FAO Penman-Monteith (FO-PM) is considered the standard method for the estimation of reference evapotranspiration (ET0) but requires various meteorological data, which are often not available. The objective of this work was to evaluate the performance of the FAO-PM method with limited meteorological data and other methods as alternatives to estimate ET0 in Jaíba-MG. The study used daily meteorological data from 2007 to 2016 of the National Institute of Meteorology’s station. Daily ET0 values were randomized, and 70% of these were used to determine the calibration parameters of the ET0 for the equations of each method under study. The remaining data were used to test the calibration against the standard method. Performance evaluation was based on Willmott’s index of agreement, confidence coefficient and root-mean-square error. When one meteorological variable was missing, either solar radiation, relative air humidity or wind speed, or in the simultaneous absence of wind speed and relative air humidity, the FAO-PM method showed the best performances and, therefore, was recommended for Jaíba. The FAO-PM method with two missing variables, one of them being solar radiation, showed intermediate performance. Methods that used only air temperature data are not recommended for the region.
DOI: 10.6084/m9.figshare.5861985
title: Oral Anticoagulation in Atrial Fibrillation: Development and Evaluation of a Mobile Health Application to Support Shared Decision-Making

description: Abstract Background: Atrial fibrillation is responsible for one in four strokes, which may be prevented by oral anticoagulation, an underused therapy around the world. Considering the challenges imposed by this sort of treatment, mobile health support for shared decision-making may improve patients’ knowledge and optimize the decisional process. Objective: To develop and evaluate a mobile application to support shared decision about thromboembolic prophylaxis in atrial fibrillation. Methods: We developed an application to be used during the clinical visit, including a video about atrial fibrillation, risk calculators, explanatory graphics and information on the drugs available for treatment. In the pilot phase, 30 patients interacted with the application, which was evaluated qualitatively and by a disease knowledge questionnaire and a decisional conflict scale. Results: The number of correct answers in the questionnaire about the disease was significantly higher after the interaction with the application (from 4.7 ± 1.8 to 7.2 ± 1.0, p &lt; 0.001). The decisional conflict scale, administered after selecting the therapy with the app support, resulted in an average of 11 ± 16/100 points, indicating a low decisional conflict. Conclusions: The use of a mobile application during medical visits on anticoagulation in atrial fibrillation improves disease knowledge, enabling a shared decision with low decisional conflict. Further studies are needed to confirm if this finding can be translated into clinical benefit.
DOI: 10.5061/dryad.r31sg.2/6.2
title: Locations

description: Approximate latitude and longitude of samped populations. NOTE: these are estimated from maps, and do not represent exact sampling locations, as GPS coordinates were not taken in the field.
DOI: 10.5061/dryad.24tt2/1
title: Treml_etal_Appendix_S2_Reef_Locations

description: List of reef IDs and centroid locations.
DOI: 10.5061/dryad.24tt2/2
title: Treml_etal_Appendix_S4_99SP_Prob_Mat_1002x1002x99

description: Row-normalized probability matrices for the 99 trait combinations as a three-dimensional array for reading in the R software environment (.RData file). Array indexing as [from reef, to reef, model taxon].
DOI: 10.5061/dryad.24tt2/3
title: Read_Treml_etal_ConMats

description: Example R script for reading and extracting data matrices from the .RData file.
DOI: 10.5061/dryad.6pr21/1
title: Experimental MR Signal Contrast Dynamics Magnitude Data Set 1

description: MR Signal Magnitude Image Data Contrast Dynamics Experiment No. 1
DOI: 10.5061/dryad.6pr21/2
title: Experimental MR Signal Contrast Dynamics Magnitude Data Set 2

description: MR Signal Magnitude Image Data Contrast Dynamics Experiment No. 2
DOI: 10.5061/dryad.6pr21/3
title: Experimental MR Signal Contrast Dynamics Magnitude Data Set 3

description: MR Signal Magnitude Image Data Contrast Dynamics Experiment No. 3
DOI: 10.5061/dryad.6pr21/4
title: Experimental MR Signal Contrast Dynamics Magnitude Data Set 4

description: MR Signal Magnitude Image Data Contrast Dynamics Experiment No. 4
DOI: 10.5061/dryad.6pr21/5
title: Experimental MR Signal Contrast Dynamics Magnitude Data Set 5

description: MR Signal Magnitude Image Data Contrast Dynamics Experiment No. 5
DOI: 10.5061/dryad.8h4v0/10
title: PAR_median_shade house

description: Photosynthetic active radiation (PAR) for shade-house
DOI: 10.5061/dryad.8h4v0/14
title: R script_landscape experiment

description: R script for the analysis of data from landscape experiment
DOI: 10.5061/dryad.8h4v0/15
title: R script_mesocosm experiment

description: R script for the analysis of data from mesocosm experiment
DOI: 10.5061/dryad.8h4v0/16
title: R script_environment_factors

description: R script for the analysis of data from landscape experiment using environmental variables
DOI: 10.5061/dryad.8h4v0/17
title: R script_graphs

description: R script for plotting figures
DOI: 10.5061/dryad.8h4v0/19
title: Climate and microclimate scripts

description: R scripts for the microclimatic figures in appendices
DOI: 10.5061/dryad.8h4v0/9
title: PAR_median_plot

description: Photosynthetic active radiation (PAR) for landscape
DOI: 10.5061/dryad.91jq5/1
title: Figure_1b_tree

description: Newick file for figure 1b. Neighbor-joining tree of 502 sorghum accessions for 265,487 SNPs
DOI: 10.5061/dryad.91jq5/2
title: Figure_S4b_tree

description: Newick file for figure S4b. Neighbor-joining tree of 502 sorghum accessions for 194,852 SNPs with MAF&gt;=0.02 and missing rate&lt;=50%
DOI: 10.5061/dryad.cv0q3/1
title: MySQL database for gene expression analysis

description: MySQL database for the transcriptional, network connectedness, molecular evolution, and GO term analysis
DOI: 10.5061/dryad.h79q4/1
title: pv42_data
DOI: 10.5061/dryad.k2d05/3
title: add_genotype-linenumber_file script

description: add_genotype-linenumber_file: This python script works on csv files that have been exported from the CLC Genomics Workbench. It adds two columns (genotype and line number) at the beginning of each csv file listed in column 1 of an input file. The input file is a csv file. The first row of the input file is considered as a header row. The script also removes the term "mapping" from the chromosome names.
DOI: 10.5061/dryad.k2d05/4
title: remove_header script

description: This python script removes the header row from each csv file that is listed in column 1 of an input csv file.
DOI: 10.5061/dryad.k2d05/5
title: merge_sort_enzymes_files

description: This perl script merges files listed in column 1 of an input csv file based on various columns within the files to be merged. For example, if chromosome number is found in column 3 and SNP position in column 4, the user could merge all files within the list by columns 3 and then by column 4.
DOI: 10.5061/dryad.k2d05/6
title: extract_SNPs_from_CLC_file

description: This python script cleans up the output files that come from the version 6.0 and higher of the CLC software. It removes any SNP calls with length greater than 1 and also all calls where the reference base is a deletion (i.e. a -). It also removes any duplicate entries in the input file.
DOI: 10.5061/dryad.k2d05/7
title: extract_SNPs_from_CLC_file script

description: This python script extracts unique and repetitive rows from an input csv file and puts them into two separate files.
DOI: 10.5061/dryad.k2d05/8
title: remove_offsite_SNPs script

description: This python script detects those SNPs that aren't within the specific distance of the restriction enzyme used for GBS DNA template preparation and puts good-hits and bad-hits into separate files.
DOI: 10.5061/dryad.k2d05/9
title: merge_CLCv6_SNP_files_with_SAM_files script

description: This python script merges the SNP detection results of CLC(version6 or higher) with the information in SAM files from CLC version 6 or higher. This script requires samtools. The user must specify the path to the samtools software path as well as the reference file name on lines 438 and 439 of this script.
DOI: 10.5061/dryad.mk159/7
title: Rickettsia alignment

description: This is a text file of a DNA sequence alignment in FASTA format.
DOI: 10.5061/dryad.mk159/8
title: Spiroplasma alignment

description: This is a text file of a DNA sequence alignment in FASTA format.
DOI: 10.5061/dryad.pf093/1
title: chicken data
DOI: 10.5061/dryad.q57h0/1
title: 1_efns_herbivory_variation

description: EFN traits and foliar herbivory per plant in each population of Anemopaegma album (around 300 individuals from 10 populations).
DOI: 10.5061/dryad.q57h0/2
title: 2_nectar_variation

description: Nectar descriptors per plant in each population of Anemopaegma album.
DOI: 10.5061/dryad.q57h0/3
title: 3_ant_assemblage

description: Ant assemblages feeding on extrafloral nectaries in each population of Anemopaegma album (around 300 individuals from 10 populations). Dataset was sampled at two different periods: t0 and t1.
DOI: 10.5061/dryad.q57h0/4
title: 4_ant_index

description: Morpho-functional descriptors of each ant species based on the EFN phenotypes, herbivory, ant size and ant recruitment.
DOI: 10.5061/dryad.q57h0/5
title: 5_across_population

description: Plant, ant and herbivorous descriptors per population (e.g. average abundance of EFNs, community-level ant traits) (N = 10 populations).
DOI: 10.5061/dryad.q57h0/6
title: 6_XY_gps

description: Latitude and longitude of each population of Anemopaegma album (N = 10 populations).
DOI: 10.5061/dryad.r31sg.1
title: Data from: Highly variable reproductive isolation among pairs of Catostomus species
DOI: 10.5061/dryad.r31sg.2/7.2
title: lib1_sucker_barcode_key

description: Barcode-ID pairs for individual fish for lane 1 of sequencing. (Please note that there are individuals included in this barcode file that belong to a different project, and are not discussed in the related paper. )
DOI: 10.5061/dryad.r31sg.2/8.2
title: lib2_sucker_barcode_key

description: Barcode-ID pairs for individual fish for lane 2 of sequencing. (Please note that there are individuals included in this barcode file that belong to a different project, and are not discussed in the related paper. )
DOI: 10.5061/dryad.r31sg.2/9.2
title: Assemblies

description: This is a tarred (compressed) file that contains assemblies to an artificial reference genome. When untarred, this file will contain &gt;800 files in .bam format, one for each individual fish. These files were produced using bwa (Burrows-Wheeler Aligner, Li and Durbin 2009).
DOI: 10.5061/dryad.s5v7b/1
title: Summary of results from coalescent simulations under isolation and secondary contact models

description: This Rdata file contains two objects, "isolation" containing the parameters and summary output of coalescent simulations under an isolation model, and "secondary contact" containing the parameters and summary output of coalescent simulations under a secondary contact model. These data are also available as tab delimited files in this repository. See README for definitions of each column name. All simulations were performed using MSMOVE (https://github.com/geneva/msmove).
DOI: 10.5061/dryad.1h7p0/1
title: Data_SmithEtAl_2015_BiologyLetters

description: File contains data on oxygen treatments and the maximum temperatures where heart beats were observed in Sceloporus tristichus eggs.  Data on egg masses are also provided.
DOI: 10.5061/dryad.25tf0/1
title: Microsatellite genotyping

description: Microsatellite genotyping of Hyacinth Macaw by population.
DOI: 10.5061/dryad.25tf0/2
title: Cytochrome b sequences of mitochondrial DNA

description: Sequencing of the cytochrome b of mitochondrial DNA of Hyacinth Macaws
DOI: 10.5061/dryad.25tf0/3
title: ND2 Sequences of mitochondrial DNA

description: NADH dehydrogenase 2 (ND2) sequencing of the mitochondrial DNA of Hyacinth macaws.
DOI: 10.5061/dryad.2q60r/1
title: Background Information

description: Questionnaire Responses
DOI: 10.5061/dryad.2q60r/10
title: Wound Data

description: Data on butchering wounds reported in questionnaire responses
DOI: 10.5061/dryad.2q60r/2
title: Consumption Data

description: Consumption data from questionnaire responses
DOI: 10.5061/dryad.2q60r/5
title: Pet data

description: Data collected from questionnaire responses on animals kept as pets.
DOI: 10.5061/dryad.2q60r/6
title: Reasons for hunting

description: Data collected from questionnaire responses
DOI: 10.5061/dryad.2q60r/7
title: Zoonotic Disease Awareness

description: Questionnaire responses
DOI: 10.5061/dryad.2q60r/9
title: Injury Data

description: Data on animal injuries reported in questionnaire responses
DOI: 10.5061/dryad.3b568/1
title: lat_by_depth_by_sp

description: Data used in quantile regression modelling.
DOI: 10.5061/dryad.3b568/2
title: Mean temperature environmental surface
DOI: 10.5061/dryad.3b568/3
title: Mean aragonite environmental surface
DOI: 10.5061/dryad.64732/1
title: BehavioralData

description: Behavioral data for all participants
DOI: 10.5061/dryad.754c6.1
title: Data from: Quantifying hummingbird preference for floral trait combinations: the role of selection on trait interactions in the evolution of pollination syndromes
DOI: 10.5061/dryad.754c6.2
title: Data from: Quantifying hummingbird preference for floral trait combinations: the role of selection on trait interactions in the evolution of pollination syndromes
DOI: 10.5061/dryad.754c6.2/1.2
title: All visits to the 48 combinations, each replicated 28 times

description: This is an excel spread sheet of the visitation data for each of the 48 combinations, summed across the 28 replicates
DOI: 10.5061/dryad.754c6.2/2.2
title: R Code for Dryad

description: This is the R code used to determine the importance of different models for explaining hummingbird visitation followed by the R code for best subsets regression