cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q2c82bjv
title: BindingDB Entry 50041484: Simple colorimetric inhibition assay of heme crystallization for high-throughput screening of antimalarial compounds.

description: Small molecule binding data for protein Histidine-rich protein, Uniprot P05227
DOI: 10.7270/q2c82bq3
title: BindingDB Entry 50043155: A thienopyrimidine derivative induces growth inhibition and apoptosis in human cancer cell lines via inhibiting Aurora B kinase activity.

description: Small molecule binding data for protein Aurora kinase B/Inner centromere protein and Serine/threonine-protein kinase Aurora, Uniprot O14965 and Q96GD4
DOI: 10.7270/q2d79cxt
title: BindingDB Entry 50043743: Investigation of fluorinated and bifunctionalized 3-phenylchroman-4-one (isoflavanone) aromatase inhibitors.

description: Small molecule binding data for protein Aromatase (CYP19), Uniprot P11511
DOI: 10.7270/q2fn17qw
title: BindingDB Entry 50044240: Inhibition of histidine decarboxylase. Derivatives of histidine.

description: Small molecule binding data for protein Histidine decarboxylase, Uniprot P16453
DOI: 10.7270/q2g73g09
title: BindingDB Entry 50042144: An investigation into the structure-activity relationships associated with the systematic modification of theß(2)-adrenoceptor agonist indacaterol.

description: Small molecule binding data for protein Beta-1 adrenergic receptor, Beta-2 adrenergic receptor, Beta-2 adrenergic receptor and beta-3 adrenergic receptor, and Dopamine receptor D2L/neurotensin receptor NTS1, Uniprot P07550, P08588, P14416, and Q8K4Z4
DOI: 10.7270/q2h133dc
title: BindingDB Entry 50043154: Selectivity of phenothiazine cholinesterase inhibitors for neurotransmitter systems.

description: Small molecule binding data for protein Histamine H1 receptor, Histamine H2 Receptor, and Serotonin 3 (5-HT3) receptor, Uniprot P25021, P35367, and P46098
DOI: 10.7270/q2hh6mdj
title: BindingDB Entry 50042674: Naphthalenyl derivatives for hitting P-gp/MRP1/BCRP transporters.

description: Small molecule binding data for protein ATP-binding cassette sub-family G member 2, Multidrug resistance-associated protein 1, and P-glycoprotein 1, Uniprot P08183, P33527, and Q9UNQ0
DOI: 10.7270/q2j104n3
title: BindingDB Entry 50043742: Discovery and optimization of N-(3-(1,3-dioxo-2,3-dihydro-1H-pyrrolo[3,4-c]pyridin-4-yloxy)phenyl)benzenesulfonamides as novel GPR119 agonists.

description: Small molecule binding data for protein G-protein coupled receptor 119, G-protein coupled receptor 119 (GPR119), and Glucose-dependent insulinotropic receptor, Uniprot Q7TQN8, Q7TQP3, and Q8TDV5
DOI: 10.7270/q2kk9ddh
title: BindingDB Entry 50044775: Discovery of potent and selective sirtuin 2 (SIRT2) inhibitors using a fragment-based approach.

description: Small molecule binding data for protein NAD-Dependent Deacetylase Sirtuin-1, NAD-dependent deacetylase sirtuin 2, and NAD-dependent protein deacetylase sirtuin-3 (SIRT3), Uniprot Q8IXJ6, Q96EB6, and Q9NTG7
DOI: 10.7270/q2m046qm
title: BindingDB Entry 50042143: Design and synthesis of diarylamines and diarylethers as cytotoxic antitumor agents.

description: Small molecule binding data for protein AXL receptor tyrosine kinase, MER intracellular domain/EGFR extracellular domain chimera, and Tyrosine-protein kinase receptor TYRO3, Uniprot P30530, Q06418, and Q12866
DOI: 10.7270/q2ms3v5v
title: BindingDB Entry 50043153: Indazoles as potential c-Met inhibitors: design, synthesis and molecular docking studies.

description: Small molecule binding data for protein Hepatocyte growth factor receptor, Uniprot P08581
DOI: 10.7270/q2n58nqj
title: BindingDB Entry 50042673: Evaluation of adamantane hydroxamates as botulinum neurotoxin inhibitors: synthesis, crystallography, modeling, kinetic and cellular based studies.

description: Small molecule binding data for protein Botulinum neurotoxin type A, Uniprot P10845
DOI: 10.7270/q2np25ww
title: BindingDB Entry 50043741: Correlation between chemotype-dependent binding conformations of HSP90a/ß and isoform selectivity-Implications for the structure-based design of HSP90a/ß selective inhibitors for treating neurodegenerative diseases.

description: Small molecule binding data for protein Glucose regulated protein 94kDa (Grp94) and Heat shock protein 75 kDa, mitochondrial, Uniprot P14625 and Q12931
DOI: 10.7270/q2pc340d
title: BindingDB Entry 50044782: Expanding the results of a high throughput screen against an isochorismate-pyruvate lyase to enzymes of a similar scaffold or mechanism.

description: Small molecule binding data for protein P-protein and Salicylate synthetase, Irp9, Uniprot P0A9J8
DOI: 10.7270/q2qr4zd6
title: BindingDB Entry 50042142: A focused sulfated glycoconjugate Ugi library for probing heparan sulfate-binding angiogenic growth factors.

description: Small molecule binding data for protein Acidic fibroblast growth factor, Basic fibroblast growth factor, and Vascular endothelial growth factor A, Uniprot P05230, P09038, and P15692
DOI: 10.7270/q2rj4kw5
title: BindingDB Entry 50043152: Evaluation of adenine as scaffold for the development of novel P2X3 receptor antagonists.

description: Small molecule binding data for protein P2X2/P2X3 receptor, Uniprot P49654
DOI: 10.7270/q2rx9ddh
title: BindingDB Entry 50042672: Synthesis and biological evaluation of novel tryptoline derivatives as indoleamine 2,3-dioxygenase (IDO) inhibitors.

description: Small molecule binding data for protein Indoleamine 2,3-dioxygenase, Uniprot P14902
DOI: 10.7270/q2st7rcq
title: BindingDB Entry 50044245: Inhibition of four human serine proteases by substituted benzamidines.

description: Small molecule binding data for protein Complement C1s, Plasminogen, and Prothrombin, Uniprot P00734, P00747, and P09871
DOI: 10.7270/q2vh5q4x
title: BindingDB Entry 50042141: Synthesis and optimization of substituted furo[2,3-d]-pyrimidin-4-amines and 7H-pyrrolo[2,3-d]pyrimidin-4-amines as ACK1 inhibitors.

description: Small molecule binding data for protein Activated CDC42 kinase 1, JAK3/JAK1, SRC, Tyrosine kinase non-receptor protein 2, Vascular endothelial growth factor receptor 2, and Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2), Uniprot O54967, P06239, P35968, P52333, Q02763, and Q07912
DOI: 10.7270/q2xk8h3f
title: BindingDB Entry 50044244: 5-Cyano-2'-deoxyuridine 5'-phosphate: a potent competitive inhibitor of thymidylate synthetase.

description: Small molecule binding data for protein Thymidylate Synthase (TS), Uniprot P00469
DOI: 10.7270/q2xw4md9
title: BindingDB Entry 50044780: DNA repair and redox activities and inhibitors of apurinic/apyrimidinic endonuclease 1/redox effector factor 1 (APE1/Ref-1): a comparative analysis and their scope and limitations toward anticancer drug development.

description: Small molecule binding data for protein Apurinic-apyrimidinic endonuclease 1 (APE-1), Uniprot P27695
DOI: 10.7270/q2028szd
title: BindingDB Entry 50043158: The development of a new class of inhibitors for betaine-homocysteine S-methyltransferase.

description: Small molecule binding data for protein Betaine--homocysteine S-methyltransferase 1, Uniprot Q93088 and V9HWA4
DOI: 10.7270/q20g3mg9
title: BindingDB Entry 50042678: Cyclopropyl- and methyl-containing inhibitors of neuronal nitric oxide synthase.

description: Small molecule binding data for protein Nitric Oxide Synthase, endothelial, Nitric Oxide Synthase, inducible, and Nitric-oxide synthase, brain, Uniprot P29473, P29476, and P29477
DOI: 10.7270/q20z74rf
title: BindingDB Entry 50043746: Synthesis and structure-activity relationship of 2-adamantylmethyl tetrazoles as potent and selective inhibitors of human 11ß-hydroxysteroid dehydrogenase type 1 (11ß-HSD1).

description: Small molecule binding data for protein 11-beta-hydroxysteroid dehydrogenase 1, Cytochrome P450 1A, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), and Pregnane X receptor (PXR), Uniprot O75469, P05177, P10635, P11712, P28845, P33261, and P50172
DOI: 10.7270/q21c1zd2
title: BindingDB Entry 50044251: Nicotinamide adenine dinucleotide phosphate-decanaldehyde adduct as an inhibitor of beef brain NADP-linked aldehyde reductase.

description: Small molecule binding data for protein Aldose reductase (ALR2), Uniprot P16116
DOI: 10.7270/q2319x65
title: BindingDB Entry 50042147: 6-Carboxymethyl-2-azabicyclo[2.2.1]heptane enantiomers: muscarinic activities of rigid analogues of arecoline

description: Small molecule binding data for protein Muscarinic acetylcholine receptor M1, Uniprot P08482
DOI: 10.7270/q25b043m
title: BindingDB Entry 50044786: Design and synthesis of Lapatinib derivatives containing a branched side chain as HER1/HER2 targeting antitumor drug candidates.

description: Small molecule binding data for protein Epidermal growth factor receptor, Epidermal growth factor receptor and ErbB2 (HER1 and HER2), Platelet-derived growth factor receptor beta, Tyrosine-protein kinase Kit (Kit), and Vascular endothelial growth factor receptor 2, Uniprot P00533, P04626, P09619, P10721, and P35968
DOI: 10.7270/q26t0nxq
title: BindingDB Entry 50042146: Optical isomers of the H1 antihistamine terfenadine: synthesis and activity

description: Small molecule binding data for protein Histamine H1 receptor, Uniprot P31389
DOI: 10.7270/q28w3fvs
title: BindingDB Entry 50044249: A manual method for applying the Hansch approach to drug design.

description: Small molecule binding data for protein Xanthine oxidase, Uniprot P47989
DOI: 10.7270/q2930vrn
title: BindingDB Entry 50044785: ¿-Hydroxyethyl piperidine iminosugar and N-alkylated derivatives: a study of their activity as glycosidase inhibitors and as immunosuppressive agents.

description: Small molecule binding data for protein Lysosomal alpha-mannosidase, Uniprot O00754
DOI: 10.7270/q2b859bk
title: BindingDB Entry 50041503: Design, synthesis and melatoninergic activity of new unsubstituted and beta,beta'-difunctionalised 2,3-dihydro-1H-pyrrolo[3,2,1-ij]quinolin-6-alkanamides.

description: Small molecule binding data for protein Melatonin 1C, Uniprot P49219
DOI: 10.7270/q2cr5vq8
title: BindingDB Entry 50042675: Potent elastase inhibitors from cyanobacteria: structural basis and mechanisms mediating cytoprotective and anti-inflammatory effects in bronchial epithelial cells.

description: Small molecule binding data for protein Leukocyte elastase, Uniprot P08246
DOI: 10.7270/q2dn46kh
title: BindingDB Entry 50044248: Stereoelectronic factors in the binding of substrate analogues and inhibitors to purine nucleoside phosphorylase isolated from human erythrocytes.

description: Small molecule binding data for protein Purine nucleoside phosphorylase, Uniprot P00491
DOI: 10.7270/q2dv1mg2
title: BindingDB Entry 50044784: Structure-activity relationships of the thujaplicins for inhibition of human tyrosinase.

description: Small molecule binding data for protein Tyrosinase, Uniprot O42713 and P14679
DOI: 10.7270/q2h133hq
title: BindingDB Entry 50043750: Ligands of the neuropeptide Y Y2 receptor.

description: Small molecule binding data for protein Neuropeptide Y receptor type 1, Neuropeptide Y receptor type 2, and Neuropeptide Y receptor type 5 ( NPY Y5), Uniprot P25929, P49146, and Q15761
DOI: 10.7270/q2jd4z9v
title: BindingDB Entry 50044247: Design of species- or isozyme-specific enzyme inhibitors. 3. Species and isozymic differences between mammalian and bacterial adenylate kinases in substituent tolerance in an enzyme-substrate complex.

description: Small molecule binding data for protein Adenylate kinase 2 and Adenylate kinase 3 alpha like 1, Uniprot P29410 and P29411
DOI: 10.7270/q2jm2c77
title: BindingDB Entry 50044783: Discovery and structure-activity relationship studies of irreversible benzisothiazolinone-based inhibitors against Staphylococcus aureus sortase A transpeptidase.

description: Small molecule binding data for protein Sortase
DOI: 10.7270/q2k075js
title: BindingDB Entry 50042151: Macrolide-type motilin receptor agonists: Assessment of the biological value of the 2- and 4-hydroxyl groups of acid-stable 8,9-anhydroerythromycin A 6,9-hemiacetals

description: Small molecule binding data for protein Motilin receptor
DOI: 10.7270/q2ks6ssx
title: BindingDB Entry 50041500: Structure-activity studies and analgesic efficacy of N-(3-pyridinyl)-bridged bicyclic diamines, exceptionally potent agonists at nicotinic acetylcholine receptors.

description: Small molecule binding data for protein Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit, Uniprot P17787 and P43681
DOI: 10.7270/q2ms3v7r
title: BindingDB Entry 50043749: The synthesis and comparative receptor binding affinities of novel, isomeric pyridoindolobenzazepine scaffolds.

description: Small molecule binding data for protein Dopamine receptor D2L/neurotensin receptor NTS1, Histamine H1 receptor, Histamine H2 Receptor, Serotonin 3 (5-HT3) receptor, and Sigma, Uniprot P14416, P25021, P35367, P46098, and Q99720
DOI: 10.7270/q2p270p4
title: BindingDB Entry 50044246: Antidepressant agents. 9. 3,3-Diphenylcyclobutylamines, a new class of central stimulants.

description: Small molecule binding data for protein Norepinephrine transporter and SLC6A4, Uniprot O55192 and Q60857
DOI: 10.7270/q2qj7jhn
title: BindingDB Entry 50041499: Optimization of 1,3,4-benzotriazepine-based CCK(2) antagonists to obtain potent, orally active inhibitors of gastrin-mediated gastric acid secretion.

description: Small molecule binding data for protein Cholecystokinin B receptor and Cholecystokinin receptor, Uniprot P30552, P32238, and P32239
DOI: 10.7270/q2qj7jpw
title: BindingDB Entry 50043160: Evaluation of thiazole containing biaryl analogs as diacylglycerol acyltransferase 1 (DGAT1) inhibitors.

description: Small molecule binding data for protein Diacylglycerol O-acyltransferase 1 (DGAT1), Uniprot O75907
DOI: 10.7270/q2qz2cbk
title: BindingDB Entry 50042680: Biotransformation of LASSBio-579 and pharmacological evaluation of p-hydroxylated metabolite a N-phenylpiperazine antipsychotic lead compound.

description: Small molecule binding data for protein 5-Hydroxytryptamine receptor 2C (5-HT2C), Adrenergic receptor alpha, Alpha adrenergic receptor 1A and 1B, Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor, Dopamine receptors; D2 & D4, and Serotonin (5-HT) receptor, Uniprot P14842, P15823, P19327, P21917, P22909, P28335, and P61169
DOI: 10.7270/q2rf5wh9
title: BindingDB Entry 50043748: Synthesis and activity of substituted heteroaromatics as positive allosteric modulators fora4ß2a5 nicotinic acetylcholine receptors.

description: Small molecule binding data for protein Nicotinic acetylcholine receptor alpha4/beta2/alpha5, Uniprot P17787, P30532, and P43681
DOI: 10.7270/q2t43vqb
title: BindingDB Entry 50044781: Discovery of substituted 6-pheny-3H-pyridazin-3-one derivatives as novel c-Met kinase inhibitors.

description: Small molecule binding data for protein Hepatocyte growth factor receptor, Uniprot P08581
DOI: 10.7270/q2v69ktn
title: BindingDB Entry 50041498: Discovery of new C3aR ligands. Part 1: arginine derivatives.

description: Small molecule binding data for protein C3a anaphylatoxin chemotactic receptor, Uniprot Q16581
DOI: 10.7270/q2v989gh
title: BindingDB Entry 50043159: Stereoselective synthesis and anti-proliferative effects on prostate cancer evaluation of 5-substituted-3,4-diphenylfuran-2-ones.

description: Small molecule binding data for protein 3-phosphoinositide dependent protein kinase-1, Uniprot O15530
DOI: 10.7270/q2vq341v
title: BindingDB Entry 50042679: Synthesis of derivatives of methyl rosmarinate and their inhibitory activities against matrix metalloproteinase-1 (MMP-1).

description: Small molecule binding data for protein Collagenase, Matrix metalloproteinase-1 (MMP1), Matrix metalloproteinase-12 (MMP12), and Stromelysin-1, Uniprot P03956, P08253, P08254, P14780, P39900, and P45452
DOI: 10.7270/q2w66n71
title: BindingDB Entry 50043747: Synthesis/biological evaluation of hydroxamic acids and their prodrugs as inhibitors for Botulinum neurotoxin A light chain.

description: Small molecule binding data for protein Botulinum neurotoxin type A, Uniprot P10845
DOI: 10.7270/q2z89dqv
title: BindingDB Entry 50042148: Synthesis, biological activity and electrostatic properties of 3-[2-(dimethylamino)ethyl]-5-[(3-amino-1,2,4-thiadiazol-5-yl)methyl]-1H-indole, a novel 5-HT1D receptor agonist.

description: Small molecule binding data for protein Serotonin 1d (5-HT1d) receptor, Uniprot P79400
DOI: 10.7270/q20003j1
title: BindingDB Entry 50043754: Discovery of thiazolylpyridinone SCD1 inhibitors with preferential liver distribution and reduced mechanism-based adverse effects.

description: Small molecule binding data for protein Acyl-CoA desaturase 1 and Stearoyl-CoA desaturase 1, Uniprot O00767 and P13516
DOI: 10.7270/q21n82qr
title: BindingDB Entry 50044787: Implications of N-capped urea/thiourea and C-capped 3-(1-piperazinyl)-1,2-benzisothiazole with bridging Gly-Val/Phe-Gly-Val-Pro as therapeutic targets.

description: Small molecule binding data for protein Urease, Uniprot P07374
DOI: 10.7270/q2222w2b
title: BindingDB Entry 50042155: TBA

description: Small molecule binding data for protein Motilin receptor, Uniprot O43193
DOI: 10.7270/q22r3svp
title: BindingDB Entry 50041505: Synthesis and biological activity of nociceptin/orphanin FQ analogues substituted in position 7 or 11 with Calpha,alpha-dialkylated amino acids.

description: Small molecule binding data for protein Nociceptin receptor and Nociceptin/Orphanin FQ, NOP receptor, Uniprot P35370, P35377, P41146, and P47748
DOI: 10.7270/q22v2hj0
title: BindingDB Entry 50043165: Synthesis and evaluation of a conditionally-silent agonist for thea7 nicotinic acetylcholine receptor.

description: Small molecule binding data for protein Neuronal acetylcholine receptor protein alpha-7 subunit, Uniprot P36544
DOI: 10.7270/q2377b16
title: BindingDB Entry 50042685: Synthesis and structure-activity relationship studies of novel dual inhibitors of soluble epoxide hydrolase and 5-lipoxygenase.

description: Small molecule binding data for protein 5-lipoxygenase/FLAP and Epoxide hydratase, Uniprot P09917 and P34913
DOI: 10.7270/q23r0vbz
title: BindingDB Entry 50043753: Cholinesterase inhibitory activity versus aromatic core multiplicity: a facile green synthesis and molecular docking study of novel piperidone embedded thiazolopyrimidines.

description: Small molecule binding data for protein Acetylcholinesterase and Butyrylcholinesterase (BuChE), Uniprot O42275 and P81908
DOI: 10.7270/q2445p0d
title: BindingDB Entry 50044258: TBA

description: Small molecule binding data for protein Uracil nucleotide/cysteinyl leukotriene receptor, Uniprot Q13304
DOI: 10.7270/q2542q4s
title: BindingDB Entry 50044250: Thymidylate synthetase inhibitors. Synthesis of N-substituted 5-aminomethyl-2'-deoxyuridine 5'-phosphates.

description: Small molecule binding data for protein Thymidylate synthase, Uniprot P07607 and Q2TA32
DOI: 10.7270/q25t3msb
title: BindingDB Entry 50042154: TBA

description: Small molecule binding data for protein HTR4 and Serotonin 4 (5-HT4) receptor, Uniprot O70528
DOI: 10.7270/q26h4jmv
title: BindingDB Entry 50041504: SAR studies on thiazolo[4,5-d]pyrimidine based CXCR2 antagonists involving a novel tandem displacement reaction.

description: Small molecule binding data for protein Interleukin-8 receptors, CXCR2, Uniprot P25025
DOI: 10.7270/q26m388q
title: BindingDB Entry 50043164: 2-Aminothiazole based P2Y(1) antagonists as novel antiplatelet agents.

description: Small molecule binding data for protein Purinergic receptor P2Y1, Uniprot P47900
DOI: 10.7270/q27082rh
title: BindingDB Entry 50042684: Synthesis, pharmacological evaluation and QSAR modeling of mono-substituted 4-phenylpiperidines and 4-phenylpiperazines.

description: Small molecule binding data for protein Dopamine receptor D2L/neurotensin receptor NTS1 and Monoamine oxidase, Uniprot P14416 and P21396
DOI: 10.7270/q27h1m2p
title: BindingDB Entry 50043752: Inhibition of LOX by flavonoids: a structure-activity relationship study.

description: Small molecule binding data for protein 5-lipoxygenase/FLAP and Lipoxygenase-1, Uniprot P08170 and P09917
DOI: 10.7270/q29k4ch2
title: BindingDB Entry 50042153: TBA

description: Small molecule binding data for protein Integrin alpha-IIb/beta-3, Uniprot P05106 and P08514
DOI: 10.7270/q2bc40zk
title: BindingDB Entry 50043163: Design, synthesis and evaluation of inhibitor of apoptosis protein (IAP) antagonists that are highly selective for the BIR2 domain of XIAP.

description: Small molecule binding data for protein X-linked inhibitor of apoptosis protein (XIAP), Uniprot P98170
DOI: 10.7270/q2br8th0
title: BindingDB Entry 50042683: 2,3-diarylpropenoic acids as selective non-steroidal inhibitors of type-5 17ß-hydroxysteroid dehydrogenase (AKR1C3).

description: Small molecule binding data for protein 17-beta-Hydroxysteroid Dehydrogenase 5 (17-beta-HSD5, AKR1C3), Aldo-keto reductase family 1 member C1, and Aldo-keto reductase family 1 member C2, Uniprot P42330, P52895, and Q04828
DOI: 10.7270/q2c82bs0
title: BindingDB Entry 50043751: Structural studies, homology modeling and molecular docking of novel non-competitive antagonists of GluK1/GluK2 receptors.

description: Small molecule binding data for protein Grik2, Uniprot Q13002
DOI: 10.7270/q2f76dvh
title: BindingDB Entry 50042152: Non-peptide fibrinogen receptor antagonists. 3. design and discovery of a centrally constrained inhibitor

description: Small molecule binding data for protein Integrin alpha-IIb/beta-3, Uniprot P05106 and P08514
DOI: 10.7270/q2g1627j
title: BindingDB Entry 50043162: Synthesis, structure-activity relationships, and in vivo efficacy of the novel potent and selective anaplastic lymphoma kinase (ALK) inhibitor 5-chloro-N2-(2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl)-N4-(2-(isopropylsulfonyl)phenyl)pyrimidine-2,4-diamine (LDK378) currently in phase 1 and phase

description: Small molecule binding data for protein ALK tyrosine kinase receptor, Hepatocyte growth factor receptor, Insulin receptor, Insulin-like growth factor I receptor, JAK3/JAK1, Kinesin-1 heavy chain/ Tyrosine-protein kinase receptor RET, MAP kinase signal-integrating kinase 2, Neurotrophic tyrosine kinase receptor, Neurotrophic tyrosine kinase receptor type 2, Platelet-derived growth factor receptor, Proto-oncogene tyrosine-protein kinase ROS, Rho-associated protein kinase, Testis-specific serine/threonine-protein kinase 1, Transcription factor ETV6, Tyrosine-protein kinase ABL1, Tyrosine-protein kinase BTK, Tyrosine-protein kinase JAK1, Tyrosine-protein kinase JAK2, Tyrosine-protein kinase SYK, Tyrosine-protein kinase ZAP-70, Tyrosine-protein kinase receptor FLT3, and p21-Activated kinase 2 (PAK2), Uniprot O60674, O75116, P00519, P04629, P06213, P07949, P08069, P08581, P08922, P16234, P23458, P36888, P41212, P43403, P43405, P52333, Q06187, Q13177, Q16620, Q9BXA7, Q9HBH9, and Q9UM73
DOI: 10.7270/q2gh9k9m
title: BindingDB Entry 50042682: Design, synthesis and SAR of piperidyl-oxadiazoles as 11ß-hydroxysteroid dehydrogenase 1 inhibitors.

description: Small molecule binding data for protein 11-beta-hydroxysteroid dehydrogenase 1, Uniprot P28845
DOI: 10.7270/q2hd7x6x
title: BindingDB Entry 50044255: TBA

description: Small molecule binding data for protein Epidermal growth factor receptor, Hepatocyte growth factor receptor, and Insulin receptor, Uniprot P00533, P06213, and P08581
DOI: 10.7270/q2hm5b1z
title: BindingDB Entry 50044791: Potent nonimmunosuppressive cyclophilin inhibitors with improved pharmaceutical properties and decreased transporter inhibition.

description: Small molecule binding data for protein ATP-binding cassette sub-family G member 2, Bile salt export pump (BSEP), Cyclophilin A, Cyclophilin B (CypB), Cytochrome P450 2C19, Cytochrome P450 2C8, Cytochrome P450 2D6 (2D6), Cytochrome P450 3A, Multidrug resistance-associated protein 2 (MRP2), P-glycoprotein 1, Peptidyl-prolyl cis-trans isomerase F, mitochondrial, Solute carrier organic anion transporter family member 1B1 (OATP1B1), and Solute carrier organic anion transporter family member 1B3 (OATP1B3), Uniprot O95342, P08183, P08684, P10632, P10635, P23284, P30405, P33261, P62937, Q92887, Q9NPD5, Q9UNQ0, and Q9Y6L6