cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.15473/1901511
title: ARIS Acoustic Camera Data Around a 5kW In-River Turbine from Tanana River Test Site

description: Four days (June 14-17, 2021) of ARIS acoustic camera data from the main research barge of the Tanana River Test Site operated by UAF. Data are collected sidelooking with the turbine in part of the field of view. This data was collected as part of a fish collision risk study. An acoustic camera was used rather than a traditional underwater camera due to the high levels of suspended sediments at the Tanana River Test Site.
DOI: 10.6073/pasta/5ed322c072dde9a3c8b7d888a7256aee
title: Jornada Basin LTER Cross-scale Interactions Study (CSIS) Block 5 meteorological station: 30-minute soil volumetric water content data: 2013 - ongoing

description: 30-minute Soil Moisture data at 10 cm at CSIS Block-5. Collection of soil volumetric water content data at Jornada LTER Cross-scale Interactions Study (CSIS) blocks, New Mexico, supports the environmental monitoring objectives of the Jornada LTER monitoring program that look at plant-soil water dynamics. Soil volumetric water content is measured at 10 cm depth at 3 locations at each of the 4 plots per block. The locations in each plot are under bare soil, under perennial grass, and under shrub. Volumetric water content, bulk electrical conductivity, soil temperature, and bulk dielectric permittivity are recorded every 30 minutes at an automated meteorological station installed at Jornada LTER CSIS Block-5 site. This is an ONGOING dataset.
DOI: 10.15151/esrf-es-998583034
title: Structure of metalloproteins, membrane proteins, filamentous sarcomer proteins, and virus particles

description: Our work focusses on biological nitrogen fixation by Nitrogenase, on metalloenzymes and integral membrane proteins of bacterial and archaeal respiratory systems (Andrade/Einsle/Wohlwend), the working mechanism and regulation of medically relevant membrane proteins and complexes and their defects leading to pathologies (Hunte), bacterial antibiotic resistance factors and viral and bacterial proteins bound to their targets or inhibitors, and their interactions with glycans (Stehle), human S100 proteins involved in nutritional immunity, USP18 enforcing the endogenous antiviral interferon response, and the respiratory complex NQR of V. cholerae (Fritz), LDL lipoprotein particles with low resolution data collection and phasing to find envelopes of parts of membrane proteins escaping conventional methods (Baumstark/Lunin), and on multi-domain components of the sarcomeric filamentous protein titin and their binding to the E3 ubiquitin ligase MuRF1 and the central myosin rod-domain (Mayans).
DOI: 10.6084/m9.figshare.21670027.v1
title: Eleven years of Progress Testing at Unicamp: a test validity study

description: Abstract: Introduction: The Medical School of the State University of Campinas (UNICAMP) has been testing the cumulative cognitive acquisition among its students through the Progress Test (PT) for over a decade, making it possible to analyze the utility of the test as a strategy to support pedagogical decisions and to point out the main threats to its validity. Objective: To provide an analysis of the validity of the PT, explaining opportunities for its use, especially in determining standards of cognitive sufficiency for progression, standards of cognitive sufficiency at the end of the course, and identification of students at risk. Method: Retrospective observational study of historical series of successive written tests performed to analyze cognitive accumulation, covering a period from 2006 to 2016, totaling 11 years and 6 consecutive classes. At each instance of measurement (test application), the study uses a mixed model where exposure (test performance) and outcome (test score) are evaluated at the same time point, characterizing a cross-sectional study, the successive results of which will generate the cognitive growth curves. Result: A cognitive accumulation of around 6 percentage points was observed with each new test. Students, upon completing the 6th year, scored around 65.7% (± 9.1). A “floor effect” was determined for each test to identify students with below-average performance, which in general was about 1.5 SD below the average of the respective class. Conclusion: TP-Unicamp offers reliable data to support important pedagogical decisions, such as the identification of students at academic risk for low performance, criteria for progression and cognitive performance at the end of the course. As reliability is influenced by sampling, increasing the number of items in each test and increasing the frequency of tests could represent strategies to overcome potential limitations.
DOI: 10.6084/m9.figshare.21670027
title: Eleven years of Progress Testing at Unicamp: a test validity study

description: Abstract: Introduction: The Medical School of the State University of Campinas (UNICAMP) has been testing the cumulative cognitive acquisition among its students through the Progress Test (PT) for over a decade, making it possible to analyze the utility of the test as a strategy to support pedagogical decisions and to point out the main threats to its validity. Objective: To provide an analysis of the validity of the PT, explaining opportunities for its use, especially in determining standards of cognitive sufficiency for progression, standards of cognitive sufficiency at the end of the course, and identification of students at risk. Method: Retrospective observational study of historical series of successive written tests performed to analyze cognitive accumulation, covering a period from 2006 to 2016, totaling 11 years and 6 consecutive classes. At each instance of measurement (test application), the study uses a mixed model where exposure (test performance) and outcome (test score) are evaluated at the same time point, characterizing a cross-sectional study, the successive results of which will generate the cognitive growth curves. Result: A cognitive accumulation of around 6 percentage points was observed with each new test. Students, upon completing the 6th year, scored around 65.7% (± 9.1). A “floor effect” was determined for each test to identify students with below-average performance, which in general was about 1.5 SD below the average of the respective class. Conclusion: TP-Unicamp offers reliable data to support important pedagogical decisions, such as the identification of students at academic risk for low performance, criteria for progression and cognitive performance at the end of the course. As reliability is influenced by sampling, increasing the number of items in each test and increasing the frequency of tests could represent strategies to overcome potential limitations.
DOI: 10.15151/esrf-es-968518286
title: Identifying the imposter in inks of highly active Pt-alloyed catalysts for hydrogen PEMFCs

description: One of the main bottlenecks of proton exchange membrane fuel cells (PEMFC) technology is the inefficient catalyst for cathodic oxygen reduction reaction, limiting their efficiency. Pt-alloyed catalysts, either shaped-controlled octahedra oh-PtNiIr or PtCo intermetallics, exhibit significantly increased activity than commercial Pt nanoparticles but only in laboratory measurements. The ink nature is expected to play a critical role in PEMFC devices, as the catalyst layer manufactured from the ink has to ensure good proton and electron conductivity to the active sites on the catalyst surface, which is difficult in the case of highly active catalysts. Here we propose a study allowing an understanding of the catalyst-support-ionomer interface formation. We plan to perform an in-situ X-ray Diffraction experiment enabling reconstruction of the catalyst local environment from the angstrom to the nanometre scale at each step of the ink and catalyst layer manufacturing.
DOI: 10.6084/m9.figshare.21670030
title: Relationship between actinic keratosis and malignant skin lesions on the eyelid

description: ABSTRACT Purpose: To evaluate the variables possibly related to actinic keratosis and malignant skin lesions on the eyelid. Methods: A prospective study of patients with suspected eyelid malignancy was conducted. The participants underwent a 2-mm punch biopsy at two opposite sites of the lesion for diagnosis, and the results were compared with those of the histopathological study of the surgical excised specimen. The patients with an actinic keratosis component were divided into two groups (actinic keratosis-associated malignancy and actinic keratosis alone), which were compared for the following variables: age, disease duration, largest diameter, tumor area, Fitzpatrick classification, sex, tumor site and margin involvement. A cluster analysis was also performed. Results: We analyzed 174 lesions, of which 50 had an actinic keratosis component. Actinic keratosis was associated with squamous cell carcinoma in 22% of the cases and to basal cell carcinoma in 38%, which shows that both neoplasms may have contiguous actinic keratosis. Statistical analysis revealed no significant difference among the variables. In a cluster analysis, four groups were identified with malignant lesions in the medial canthus with the largest mean diameter and area. All margin involvements on the lower eyelid were related to malignancy, which means that all cases with margin involvement had an almost 100% risk of malignancy. Conclusions: Larger actinic keratosis lesions in the medial canthus and lesions with margin involvement on the lower eyelid have a greater probability of malignant association.
DOI: 10.6084/m9.figshare.21670030.v1
title: Relationship between actinic keratosis and malignant skin lesions on the eyelid

description: ABSTRACT Purpose: To evaluate the variables possibly related to actinic keratosis and malignant skin lesions on the eyelid. Methods: A prospective study of patients with suspected eyelid malignancy was conducted. The participants underwent a 2-mm punch biopsy at two opposite sites of the lesion for diagnosis, and the results were compared with those of the histopathological study of the surgical excised specimen. The patients with an actinic keratosis component were divided into two groups (actinic keratosis-associated malignancy and actinic keratosis alone), which were compared for the following variables: age, disease duration, largest diameter, tumor area, Fitzpatrick classification, sex, tumor site and margin involvement. A cluster analysis was also performed. Results: We analyzed 174 lesions, of which 50 had an actinic keratosis component. Actinic keratosis was associated with squamous cell carcinoma in 22% of the cases and to basal cell carcinoma in 38%, which shows that both neoplasms may have contiguous actinic keratosis. Statistical analysis revealed no significant difference among the variables. In a cluster analysis, four groups were identified with malignant lesions in the medial canthus with the largest mean diameter and area. All margin involvements on the lower eyelid were related to malignancy, which means that all cases with margin involvement had an almost 100% risk of malignancy. Conclusions: Larger actinic keratosis lesions in the medial canthus and lesions with margin involvement on the lower eyelid have a greater probability of malignant association.
DOI: 10.6084/m9.figshare.21670032
title: Biological properties of Schinus terebinthifolia Raddi essential oil

description: Abstract Schinus terebinthifolia Raddi green fruits essential oil (EO) was evaluated regarding its phytochemical profile, antimicrobial and cytotoxic activities, and toxicity. Gas chromatography with mass spectrometry was applied to identify its constituents, thereafter the minimum inhibitory concentration, minimum bactericidal and fungicidal concentrations, and its antibiofilm activity were evaluated. The EO cytotoxicity was assessed in tumor and non-tumor human cells, and in vivo toxicity was evaluated in a Galleria mellonella model. The major constituents of S. terebinthifolia EO were alpha-phellandrene and beta-phellandrene. The EO had a weak activity against all strains of Candida albicans (MIC 1000μg/mL) and had no activity against non-albicans strains, bacteria, and C. albicans biofilm. Cytostatic activity against all tumor cell lines was shown. Additionally, cell viability remained at EO concentrations up to 62.5 μg/mL. At 16 mg/mL, 50% hemolysis was observed, and it had low toxicity in vivo. Overall, the S. terebinthifolia EO was characterized by low antimicrobial and antibiofilm activities, with no evidence of toxicity to human tumor and non-tumor cells.
DOI: 10.6084/m9.figshare.21670032.v1
title: Biological properties of Schinus terebinthifolia Raddi essential oil

description: Abstract Schinus terebinthifolia Raddi green fruits essential oil (EO) was evaluated regarding its phytochemical profile, antimicrobial and cytotoxic activities, and toxicity. Gas chromatography with mass spectrometry was applied to identify its constituents, thereafter the minimum inhibitory concentration, minimum bactericidal and fungicidal concentrations, and its antibiofilm activity were evaluated. The EO cytotoxicity was assessed in tumor and non-tumor human cells, and in vivo toxicity was evaluated in a Galleria mellonella model. The major constituents of S. terebinthifolia EO were alpha-phellandrene and beta-phellandrene. The EO had a weak activity against all strains of Candida albicans (MIC 1000μg/mL) and had no activity against non-albicans strains, bacteria, and C. albicans biofilm. Cytostatic activity against all tumor cell lines was shown. Additionally, cell viability remained at EO concentrations up to 62.5 μg/mL. At 16 mg/mL, 50% hemolysis was observed, and it had low toxicity in vivo. Overall, the S. terebinthifolia EO was characterized by low antimicrobial and antibiofilm activities, with no evidence of toxicity to human tumor and non-tumor cells.
DOI: 10.6084/m9.figshare.21670033
title: The Progress Test in gynecology and obstetrics medical residency: the national experience

description: Abstract: Introduction: The Progress Test (PT) is a comprehensive, longitudinal cognitive assessment with benefits for the learner, educational programs, and society. Although it is widely used in undergraduate courses in Brazil, there is little experience regarding its use in medical residency. This study aims to portray Febrasgo’s experience in the first four years of implementing the Resident’s Individual PT in ObGyn (TPI-GO). Experience report: The TPI-GO was implemented in 2018, being offered annually to Brazilian residents. In the last two years, the TPI-GO has been provided online. Febrasgo established criteria that allow for exemption or bonus in the theoretical test to encourage the trainees’ participation in the TPI-GO to obtain the Specialist Certification in Gynecology and Obstetrics (TEGO). Results are provided confidentially to candidates and allow self-assessment. The results of the residents’ performance from the same service are provided to the program supervisor, offering subsidies for self-assessment of quality and indicating points for improvement. Discussion: Since it was implemented, there has been an increasing number of candidates enrolled in the TPI-GO and a high adherence rate. The medians of performance of the two cohorts of residents studied showed cognitive evolution between beginners (R1) and graduates (R3), with differences attributed in part to the adverse effects of the Pandemic on training. Conclusion: The implementation of the PT in medical residency is feasible, acceptable, and shows advantages and benefits, but it requires the commitment of the organizing team, besides logistical and financial support. The results confidentiality is recommended and preserves the candidate. The possibility of granting bonuses and exemptions in the TEGO theoretical test is an excellent attraction aiming at the adhesion and adherence of residents to the PT. The TPI-GO online increases access with acceptable levels of security.
DOI: 10.6084/m9.figshare.21670033.v1
title: The Progress Test in gynecology and obstetrics medical residency: the national experience

description: Abstract: Introduction: The Progress Test (PT) is a comprehensive, longitudinal cognitive assessment with benefits for the learner, educational programs, and society. Although it is widely used in undergraduate courses in Brazil, there is little experience regarding its use in medical residency. This study aims to portray Febrasgo’s experience in the first four years of implementing the Resident’s Individual PT in ObGyn (TPI-GO). Experience report: The TPI-GO was implemented in 2018, being offered annually to Brazilian residents. In the last two years, the TPI-GO has been provided online. Febrasgo established criteria that allow for exemption or bonus in the theoretical test to encourage the trainees’ participation in the TPI-GO to obtain the Specialist Certification in Gynecology and Obstetrics (TEGO). Results are provided confidentially to candidates and allow self-assessment. The results of the residents’ performance from the same service are provided to the program supervisor, offering subsidies for self-assessment of quality and indicating points for improvement. Discussion: Since it was implemented, there has been an increasing number of candidates enrolled in the TPI-GO and a high adherence rate. The medians of performance of the two cohorts of residents studied showed cognitive evolution between beginners (R1) and graduates (R3), with differences attributed in part to the adverse effects of the Pandemic on training. Conclusion: The implementation of the PT in medical residency is feasible, acceptable, and shows advantages and benefits, but it requires the commitment of the organizing team, besides logistical and financial support. The results confidentiality is recommended and preserves the candidate. The possibility of granting bonuses and exemptions in the TEGO theoretical test is an excellent attraction aiming at the adhesion and adherence of residents to the PT. The TPI-GO online increases access with acceptable levels of security.
DOI: 10.6084/m9.figshare.21670036
title: Pediatric canalicular laceration repair using the Mini Monoka versus Masterka monocanalicular stent

description: ABSTRACT Purpose: One of the most important disadvantages of using Mini Monoka stents in pediatric canalicular laceration repair is premature stent loss. In this study, we aimed to compare clinical outcomes between the use of Mini Monoka and Masterka monocanalicular stents in children and discuss the potential causes of premature stent loss. Methods: The medical records of 36 patients who underwent surgical repair of canalicular lacerations were retrospectively reviewed. Children aged &lt;18 years who underwent canalicular laceration repair with either Mini Monoka or Masterka and had at least 6 months of follow-up after stent removal were included in the study. The patients’ demographics, mechanism of injury, type of stent used, premature stent loss, and success rate were analyzed. Success was defined as stent removal without subsequent epiphora and premature stent loss. Results: Twenty-seven children fulfilled our study criteria, and their data were included in the analyses. Mini Monoka was used in 14 patients (51.9%), whereas Masterka was used in 13 patients (48.1%). The preoperative clinical features, including age, sex, and mechanism of injury, were similar between the two groups. The mean age was 8.3 ± 5.5 years in the Mini Monoka group and 7.8 ± 5.9 years in the Masterka group (p=0.61). Three patients in the Mini Monoka group (21.4%) underwent reoperation due to premature stent loss. No premature stent loss was observed in the Masterka group. As a result, the rate of success was 78.6% in the Mini Monoka group, whereas it was 100% in the Masterka group (p=0.22). Conclusions: Even though the two groups did not show any statistically significant difference in success rate, we did not observe any premature stent loss in the Masterka group. Further studies with larger and randomized series are warranted to elaborate on these findings.
DOI: 10.6084/m9.figshare.21670036.v1
title: Pediatric canalicular laceration repair using the Mini Monoka versus Masterka monocanalicular stent

description: ABSTRACT Purpose: One of the most important disadvantages of using Mini Monoka stents in pediatric canalicular laceration repair is premature stent loss. In this study, we aimed to compare clinical outcomes between the use of Mini Monoka and Masterka monocanalicular stents in children and discuss the potential causes of premature stent loss. Methods: The medical records of 36 patients who underwent surgical repair of canalicular lacerations were retrospectively reviewed. Children aged &lt;18 years who underwent canalicular laceration repair with either Mini Monoka or Masterka and had at least 6 months of follow-up after stent removal were included in the study. The patients’ demographics, mechanism of injury, type of stent used, premature stent loss, and success rate were analyzed. Success was defined as stent removal without subsequent epiphora and premature stent loss. Results: Twenty-seven children fulfilled our study criteria, and their data were included in the analyses. Mini Monoka was used in 14 patients (51.9%), whereas Masterka was used in 13 patients (48.1%). The preoperative clinical features, including age, sex, and mechanism of injury, were similar between the two groups. The mean age was 8.3 ± 5.5 years in the Mini Monoka group and 7.8 ± 5.9 years in the Masterka group (p=0.61). Three patients in the Mini Monoka group (21.4%) underwent reoperation due to premature stent loss. No premature stent loss was observed in the Masterka group. As a result, the rate of success was 78.6% in the Mini Monoka group, whereas it was 100% in the Masterka group (p=0.22). Conclusions: Even though the two groups did not show any statistically significant difference in success rate, we did not observe any premature stent loss in the Masterka group. Further studies with larger and randomized series are warranted to elaborate on these findings.
DOI: 10.6084/m9.figshare.21670038
title: Fulminant endogenous panophthalmitis caused by Clostridium septicum infection

description: ABSTRACT We report an unusual case of fulminant endogenous Clostridium septicum panophthalmitis. A 74-year-old male patient presented with sudden amaurosis in the right eye, which in a few hours, evolved into an orbital cellulitis, endophthalmitis, anterior segment ischemia, and secondary perforation of the eye. A complete diagnostic study, which included cranial and orbital contrast-enhanced computed tomography scan, contrast-enhanced magnetic resonance imaging, blood cultures, and complete blood work, were performed. No causal agent was identified. Clostridium septicum infection caused fulminant gaseous panophthalmitis. Despite broad-spectrum antibiotic treatment, evisceration of the eyeball was necessary. The extension study showed a colon adenocarcinoma as the origin of the infection. Clostridium septicum panophthalmitis is a rare but aggressive orbital infection. This infection warrants the identification of a neoplastic process in the gastrointestinal tract in many cases not previously described.