cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.8248930
title: H2020 ENODISE: UBRI Experimental Aeroacoustic Database BLI Configuration A

description: This database contains the datasets for the aeroacoustic experiments conducted at the University of Bristol regarding Boundary Layer Ingestion configurations A1 and A2 as part of the H2020 ENODISE project. Configuration A1 consists of a propeller ingesting a zero-pressure-gradient boundary layer while A2 is a propeller ingesting an adverse pressure gradient boundary layer in a partially buried configuration. Far-field acoustics are measured using two microphone arcs, near-field measurements consist of surface static pressure and pressure fluctuations. Propeller force and torque is measured using a load cell. Flow-field measurements are obtained through hotwire anemometry. This forms part of Deliverable D3.3, see D3.3 report for further information regarding measurement techniques. Included are descriptive READMEs and instrumentation layouts. The data is in the HDF5 format and comprises mean, spectral, and other processed data types in engineering units. Now updated with D3.6 to include cleaned CAD models of both A1 and A2 configurations in STEP formats.
description: v1.0.1 - updated A2.UBRI.zip to correct static pressure rms calculation and hotwire SW Y coordinates. v1.1.0 - updated A2.UBRI.zip to more accurately reflect measured freestream velocities - replaced SW Plate Only hotwire data in A2.UBRI.zip with 2D X-wire counterparts, additional lines. - updated A1.UBRI.zip to more accurately reflect measured freestream velocities v1.2.0 - Added CAD geometry files
DOI: 10.18739/a23x83n3n
title: Radon-222 and Radium-226 seawater and ice data from Bering Sea and Chukchi Sea 2021

description: Mercury (Hg) concentrations and speciation within surface waters of the Arctic Ocean are controlled by a complex set of processes including photochemical and microbial transformations, redox reactions, and air-sea exchange of gaseous and particulate Hg species. In this study, our aim was to estimate the magnitude of volatile Hg fluxes across the air-sea interface, and examine the influence of ice cover on this process. While gas exchange in the open ocean has been modeled as a function of wind speed, the parameterization is problematic in the presence of sea ice, which can physically block gas exchange, as well as reduce fetch and dampen waves. By using measurements of Radon-222 (Rn-222) gas and it parent isotope, Radium-226 (Ra-226), to accurately measure gas exchange velocities (k), the relative impacts of chemical and biological processes on mercury distributions within the surface waters can then be deduced.
 This dataset contains Radon-222 and Radium-226 activity concentrations from R/V Sikuliaq cruise SKQ202108S in the Bering Sea, through the Bering Strait, and in shelf waters of the Chukchi Sea during May – June 2021. Samples include seawater (16 water column profiles), as well as ice cores and brine from four ice stations. At the time of the cruise, sampling locations in the Bering Sea were ice free and gas transfer velocities (k) estimated from Rn-222 deficits (with respect to Ra-226 concentrations) were in general agreement with published parameterizations of k as a function of wind speed. The springtime retreating ice edge was located at 69-70 degrees north latitude in the Chukchi Sea, and sampling locations there were located along the ice edge, in areas of open water, and at sites within the pack ice up to ~10 kilometers (km) from the ice edge. Gas transfer velocities in the marginal ice zone also reflected recent wind histories, with k values generally at the high end of or exceeding those predicted from the wind speed parameterizations.
DOI: 10.25387/g3.24581928
title: Supplemental Material for Barragan et al., 2023

description: RNAseq analysis of differential gene expression between "normal/healthy" Arabidopsis arenosa individuals and "abnormal/sick" ones. Raw read counts, processed read counts after normalization, and differential gene expression statistics can be found here.
DOI: 10.25387/g3.24581928.v1
title: Supplemental Material for Barragan et al., 2023

description: RNAseq analysis of differential gene expression between "normal/healthy" Arabidopsis arenosa individuals and "abnormal/sick" ones. Raw read counts, processed read counts after normalization, and differential gene expression statistics can be found here.
DOI: 10.6073/pasta/6ce63c067471ce075992d0189c4cebb0
title: Intertidal Crab Data in Midcoast Maine: 2018-2023

description: Invasive species have caused major disruptions to ecosystems worldwide. The European green crab invaded North America in the 1800s and is considered one of the world’s 100 worst invaders by the IUCN. Observations of spatiotemporal green crab population dynamics are essential for predicting and managing the ecological and economic impacts of this harmful invasive species. These data come from a standardized method for assessing green crab population dynamics in the rocky intertidal zone of New England and Atlantic Canada. Data was collected from 10 survey sites located along the coast of Maine from Yarmouth, ME (furthest point south), to Walpole, ME (furthest site north) from January, 2018 to November, 2023. Data was collected following the survey design described in McMahan (2020), using a 1m^2 quadrat to sample rocky intertidal habitat. The resulting data collected using this protocol has a wide range of uses, including to inform ecological research, conservation efforts, mitigation strategies, and fishery development, as well as for educational outreach purposes.
DOI: 10.5281/zenodo.10258019
title: Single-Cell RNA-Sequencing Reveals Placental Response under Environmental Stress

description: This repository provides scRNA-seq data corresponding to the manuscript "Single-Cell RNA-Sequencing Reveals Placental Response under Environmental Stress" by Van Buren, Azzara, Rangel-Moreno, de la Luz Garcia-Hernandez, Murphy, Cohen, Lin, and Park. The repository includes both count by gene matrices output from CellRanger version 6.0.1 (file names *_filtered_feature_matrix.h5 for each of the eight samples Control_1_M, Control_1_F, Control_2_M, Control_2_F, As_1_M, As_1_F, As_2_M, As_2_F), and a finalized Seurat object including cell type assignments as used for analyses in the manuscript (file name final_Seurat_obj.RData). Accompanying code used in analysis can be found at https://github.com/edvanburen/placenta_code.
DOI: 10.5281/zenodo.10258020
title: Single-Cell RNA-Sequencing Reveals Placental Response under Environmental Stress

description: This repository provides scRNA-seq data corresponding to the manuscript "Single-Cell RNA-Sequencing Reveals Placental Response under Environmental Stress" by Van Buren, Azzara, Rangel-Moreno, de la Luz Garcia-Hernandez, Murphy, Cohen, Lin, and Park. The repository includes both count by gene matrices output from CellRanger version 6.0.1 (file names *_filtered_feature_matrix.h5 for each of the eight samples Control_1_M, Control_1_F, Control_2_M, Control_2_F, As_1_M, As_1_F, As_2_M, As_2_F), and a finalized Seurat object including cell type assignments as used for analyses in the manuscript (file name final_Seurat_obj.RData). Accompanying code used in analysis can be found at https://github.com/edvanburen/placenta_code.
DOI: 10.25345/c51n7xz17
title: MassIVE MSV000093670 - Proteomic analysis of Breast cancer spheroids responder and non-responder to Trastuzumab
title: Proteomic analysis of breast cancer spheroids obtained from BT-474 cell line to characterize Trastuzumab resistance mechanism. Four conditions were examined: responder and non-responder spheroids before and after a 15-days treatment with Trastuzumab (RS_0, RS_15, nRS_0 and nRS_15).
DOI: 10.5517/ccdc.csd.cc2ftr67
title: CCDC 2259069: Experimental Crystal Structure Determination

description: Related Article: Ahmad Takallou, Munir Al-Siyabi, Sulaiman Al-Shidhani, Yazdanbakhsh Lotfi Nosood, Azizollah Habibi, Alhajaj Almaani, Muhammad U. Anwar, Ahmed Al-Harrasi|2023|Org.Biomol.Chem.|21|9530|doi:10.1039/D3OB01768K
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2ggt5y
title: CCDC 2278350: Experimental Crystal Structure Determination

description: Related Article: Leo W. T. Parsons, James C. Fettinger, Louise A. Berben|2023|Chemical Science|14|13944|doi:10.1039/D3SC03806H
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2gjft8
title: CCDC 2279920: Experimental Crystal Structure Determination

description: Related Article: Eva Zahradníková, Jean-Pascal Sutter, Petr Halaš, Bohuslav Drahoš|2023|Dalton Trans.|52|18513|doi:10.1039/D3DT02639F
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2gjyzy
title: CCDC 2280421: Experimental Crystal Structure Determination

description: Related Article: Jieyu Tang, Xi Liu, Xue Zhang, Jianzhang Zhao, Yan Wan|2023|New J.Chem.|47|22418|doi:10.1039/D3NJ04201D
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2gjz00
title: CCDC 2280422: Experimental Crystal Structure Determination

description: Related Article: Jieyu Tang, Xi Liu, Xue Zhang, Jianzhang Zhao, Yan Wan|2023|New J.Chem.|47|22418|doi:10.1039/D3NJ04201D
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2gjz11
title: CCDC 2280423: Experimental Crystal Structure Determination

description: Related Article: Jieyu Tang, Xi Liu, Xue Zhang, Jianzhang Zhao, Yan Wan|2023|New J.Chem.|47|22418|doi:10.1039/D3NJ04201D
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5281/zenodo.10058338
title: The coupling mechanism of ligands with SERT distinguishes substrates from inhibitors (raw data)

description: Raw data of the manuscript: Ligand coupling mechanism of the human serotonin transporter differentiates substrates from inhibitors


Abstract:


The presynaptic serotonin transporter (SERT) reuptakes the serotonin (5HT) released into the synaptic cleft, thus ensuring temporal and spatial regulation of serotonergic signalling. Clinically approved drugs used for the treatment of neurological disorders, including depression and anxiety modulate SERT by trapping the transporter in the outward-open conformation. Illicit drugs of abuse as amphetamines act as substrates but reverse the transport direction, thereby releasing intracellular accumulated 5HT. Both mechanisms increase extracellular 5HT levels. Stoichiometry of the transport cycle has been described by kinetic schemes, the structures of the main conformations within the transport cycle revealed static coordinates. By combining in-silico approaches with in-vitro experiments and making use of a homologous series of 5HT analogues, we decoded the essential coupling mechanism between the substrate and the transporter which triggers uptake. The free energy calculations showed that only scaffold-bound substrates can correctly close the extracellular gate by pulling on the bundle domain through long-range electrostatic interactions. The associated spatial and physico-chemical requirements define substrate and inhibitor properties, opening new possibilities for rational drug design approaches.
DOI: 10.5281/zenodo.10381879
title: The coupling mechanism of ligands with SERT distinguishes substrates from inhibitors (raw data)

description: Raw data of the manuscript: Ligand coupling mechanism of the human serotonin transporter differentiates substrates from inhibitors


Abstract:


The presynaptic serotonin transporter (SERT) reuptakes the serotonin (5HT) released into the synaptic cleft, thus ensuring temporal and spatial regulation of serotonergic signalling. Clinically approved drugs used for the treatment of neurological disorders, including depression and anxiety modulate SERT by trapping the transporter in the outward-open conformation. Illicit drugs of abuse as amphetamines act as substrates but reverse the transport direction, thereby releasing intracellular accumulated 5HT. Both mechanisms increase extracellular 5HT levels. Stoichiometry of the transport cycle has been described by kinetic schemes, the structures of the main conformations within the transport cycle revealed static coordinates. By combining in-silico approaches with in-vitro experiments and making use of a homologous series of 5HT analogues, we decoded the essential coupling mechanism between the substrate and the transporter which triggers uptake. The free energy calculations showed that only scaffold-bound substrates can correctly close the extracellular gate by pulling on the bundle domain through long-range electrostatic interactions. The associated spatial and physico-chemical requirements define substrate and inhibitor properties, opening new possibilities for rational drug design approaches.
DOI: 10.5281/zenodo.8094750
title: The coupling mechanism of ligands with SERT distinguishes substrates from inhibitors (raw data)

description: Raw data of the manuscript: Ligand coupling mechanism of the human serotonin transporter differentiates substrates from inhibitors


Abstract:


The presynaptic serotonin transporter (SERT) reuptakes the serotonin (5HT) released into the synaptic cleft, thus ensuring temporal and spatial regulation of serotonergic signalling. Clinically approved drugs used for the treatment of neurological disorders, including depression and anxiety modulate SERT by trapping the transporter in the outward-open conformation. Illicit drugs of abuse as amphetamines act as substrates but reverse the transport direction, thereby releasing intracellular accumulated 5HT. Both mechanisms increase extracellular 5HT levels. Stoichiometry of the transport cycle has been described by kinetic schemes, the structures of the main conformations within the transport cycle revealed static coordinates. By combining in-silico approaches with in-vitro experiments and making use of a homologous series of 5HT analogues, we decoded the essential coupling mechanism between the substrate and the transporter which triggers uptake. The free energy calculations showed that only scaffold-bound substrates can correctly close the extracellular gate by pulling on the bundle domain through long-range electrostatic interactions. The associated spatial and physico-chemical requirements define substrate and inhibitor properties, opening new possibilities for rational drug design approaches.
DOI: 10.5281/zenodo.8094751
title: The coupling mechanism of ligands with SERT distinguishes substrates from inhibitors (raw data)

description: Raw data of the manuscript: Ligand coupling mechanism of the human serotonin transporter differentiates substrates from inhibitors <strong>Abstract:</strong> The presynaptic serotonin transporter (SERT) reuptakes the serotonin (5HT) released into the synaptic cleft, thus ensuring temporal and spatial regulation of serotonergic signalling. Clinically approved drugs used for the treatment of neurological disorders, including depression and anxiety modulate SERT by trapping the transporter in the outward-open conformation. Illicit drugs of abuse as amphetamines act as substrates but reverse the transport direction, thereby releasing intracellular accumulated 5HT. Both mechanisms increase extracellular 5HT levels. Stoichiometry of the transport cycle has been described by kinetic schemes, the structures of the main conformations within the transport cycle revealed static coordinates. By combining <em>in-silico</em> approaches with <em>in-vitro</em> experiments and making use of a homologous series of 5HT analogues, we decoded the essential coupling mechanism between the substrate and the transporter which triggers uptake. The free energy calculations showed that only scaffold-bound substrates can correctly close the extracellular gate by pulling on the bundle domain through long-range electrostatic interactions. The associated spatial and physico-chemical requirements define substrate and inhibitor properties, opening new possibilities for rational drug design approaches.
DOI: 10.6084/m9.figshare.24808362
title: Datasets of intercrystal scatter in dual-panel Positron Emission Mammography system

description: Raw data tables from the statistical analysis of Monte Carlo simulations of intercrystal scatter events using either pixelated or monolithic LYSO crystals. The data includes total number of events classified by type of interaction (photoelectric, single Compton or multiple Compton scattering).
DOI: 10.6084/m9.figshare.24808362.v1
title: Datasets of intercrystal scatter in dual-panel Positron Emission Mammography system

description: Raw data tables from the statistical analysis of Monte Carlo simulations of intercrystal scatter events using either pixelated or monolithic LYSO crystals. The data includes total number of events classified by type of interaction (photoelectric, single Compton or multiple Compton scattering).
DOI: 10.17861/a6472fd5-7c4c-4706-9aab-7b7a76fd6d37
title: Integrating and Evaluating the Effects of Wettability and Invading Fluid Velocity on Fluid Displacement Kinetics and Ganglion Dynamics

description: Details of dynamic ganglion behaviour
DOI: 10.6084/m9.figshare.24032742.v1
title: Regional dynamic cerebral autoregulation to abrupt reductions in blood pressure in acute hypoxia (fraction of inspired oxygen; FiO2 = 12.5%).xlsx

description: Regional dynamic cerebral autoregulation to abrupt reductions in blood pressure in acute hypoxia (fraction of inspired oxygen; FiO2 = 12.5%)
DOI: 10.6084/m9.figshare.24032742.v2
title: Regional dynamic cerebral autoregulation to abrupt reductions in blood pressure in acute hypoxia (fraction of inspired oxygen; FiO2 = 12.5%).xlsx

description: Regional dynamic cerebral autoregulation to abrupt reductions in blood pressure in acute hypoxia (fraction of inspired oxygen; FiO2 = 12.5%)
DOI: 10.7910/dvn/epvgjn
title: Replication Data for: Anti-Immigrant Rhetoric and ICE Reporting Interest: Evidence from a Large-Scale Study of Web Search Data

description: This dataset contains the code and the non-Bing data to replicate the article "Anti-Immigrant Rhetoric and ICE Reporting Interest: Evidence from a Large-Scale Study of Web Search Data". For access to the Bing data, please complete the following form: https://forms.office.com/pages/responsepage.aspx?id=DQSIkWdsW0yxEjajBLZtrQAAAAAAAAAAAAN__rP-L2FUNkc4TkMwRU1XTkxBNVdESUE0NVVUWThNMC4u
DOI: 10.60600/yu/zgkzja/u7hvdd
title: User guide.pdf

description: The user guide provides a brief background of the project and outlines some useful information about the dataset.
DOI: 10.60600/yu/zgkzja/050xw9
title: Wave 1 Phone Survey Instrument.html

description: This file is part of "Calling for Health: Can Mobile Phones Improve Awareness and Takeup of Maternity Benefits?". Materials are easiest to read after downloading by using [Access Dataset &gt; Original Format ZIP].
DOI: 10.60600/yu/zgkzja/0sitph
title: PhoneSurvey_Wave3-Codebook.html

description: This file is part of "Calling for Health: Can Mobile Phones Improve Awareness and Takeup of Maternity Benefits?". Materials are easiest to read after downloading by using [Access Dataset &gt; Original Format ZIP].
DOI: 10.60600/yu/zgkzja/gynp2i
title: PhoneSurvey_Wave1-Codebook.html

description: This file is part of "Calling for Health: Can Mobile Phones Improve Awareness and Takeup of Maternity Benefits?". Materials are easiest to read after downloading by using [Access Dataset &gt; Original Format ZIP].
DOI: 10.60600/yu/zgkzja/tzjfsw
title: Follow-up CCT Survey Instrument.pdf

description: This file is part of "Calling for Health: Can Mobile Phones Improve Awareness and Takeup of Maternity Benefits?". Materials are easiest to read after downloading by using [Access Dataset &gt; Original Format ZIP].
DOI: 10.60600/yu/zgkzja/ujepqh
title: PhoneSurvey_Wave2-Codebook.html

description: This file is part of "Calling for Health: Can Mobile Phones Improve Awareness and Takeup of Maternity Benefits?". Materials are easiest to read after downloading by using [Access Dataset &gt; Original Format ZIP].
DOI: 10.60600/yu/zgkzja/5erfip
title: wave3.tab

description: This file is part of "Calling for Health: Can Mobile Phones Improve Awareness and Takeup of Maternity Benefits?". Materials are easiest to read after downloading by using [Access Dataset &gt; Original Format ZIP].
DOI: 10.60600/yu/zgkzja/exjocr
title: Wave 2 Phone Survey Instrument.html

description: This file is part of "Calling for Health: Can Mobile Phones Improve Awareness and Takeup of Maternity Benefits?". Materials are easiest to read after downloading by using [Access Dataset &gt; Original Format ZIP].
DOI: 10.60600/yu/zgkzja/ho14am
title: wave2.tab

description: This file is part of "Calling for Health: Can Mobile Phones Improve Awareness and Takeup of Maternity Benefits?". Materials are easiest to read after downloading by using [Access Dataset &gt; Original Format ZIP].
DOI: 10.60600/yu/zgkzja/hrux11
title: FollowUpSurveyCCT-Codebook.html

description: This file is part of "Calling for Health: Can Mobile Phones Improve Awareness and Takeup of Maternity Benefits?". Materials are easiest to read after downloading by using [Access Dataset &gt; Original Format ZIP].
DOI: 10.60600/yu/zgkzja/stst9c
title: Wave 3 Phone Survey Instrument.html

description: This file is part of "Calling for Health: Can Mobile Phones Improve Awareness and Takeup of Maternity Benefits?". Materials are easiest to read after downloading by using [Access Dataset &gt; Original Format ZIP].
DOI: 10.60600/yu/zgkzja/w9xmva
title: wave1.tab

description: This file is part of "Calling for Health: Can Mobile Phones Improve Awareness and Takeup of Maternity Benefits?". Materials are easiest to read after downloading by using [Access Dataset &gt; Original Format ZIP].
DOI: 10.60600/yu/zgkzja/96gobh
title: follow_up_cct.tab

description: This file is part of "Calling for Health: Can Mobile Phones Improve Awareness and Takeup of Maternity Benefits?". Materials are easiest to read after downloading by using [Access Dataset &gt; Original Format ZIP].
DOI: 10.60600/yu/zgkzja/gf5b2h
title: wave1.tab

description: This file is part of "Calling for Health: Can Mobile Phones Improve Awareness and Takeup of Maternity Benefits?". Materials are easiest to read after downloading by using [Access Dataset &gt; Original Format ZIP].