cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7516310.v1
title: Echocardiographic Assessment of Right Ventricular Function by Two-Dimensional Strain In Patients with Left-Sided Valvular Heart Disease: Comparison with Three-Dimensional Echocardiography

description: Abstract Background: Right ventricular (RV) dysfunction is a well-known predictor of mortality in patients with valvular heart disease (VHD). The assessment of RV function is often difficult due to complex geometry and hemodynamic factors. We aim to analyze RV function in patients with severe mitral and/or aortic valve disease using two-dimensional strain (2DS) imaging and conventional echocardiographic parameters, comparing it with right ventricular ejection fraction (RVEF) measured by three-dimensional echocardiography (3DE). Methods: Fifty-three patients with severe mitral and/or aortic VHD underwent complete transthoracic echocardiogram in the preoperative setting for cardiac surgery, including conventional echocardiographic parameters of RV function and speckle-tracking derived 2DS indices: RV global longitudinal strain (RVGS) and RV free wall longitudinal strain (RVFWS). Conventional echocardiographic and 2DS parameters were compared with real-time 3DE RVEF using Spearman correlation test. For comparison between two groups of patients based on the presence of RV dysfunction (normal RVEF ≥ 44% - A, abnormal RVEF &lt; 44% - B), we used nonparametric Mann-Whitney U test. ROC (receiver operating characteristic) curve analysis was used to assess the clinical utility of all RV function variables in defining RV dysfunction. P values &lt;0,05 were considered statistically significant. Results: We found a significant correlation between all parameters and RVEF (p&lt;0.05), with best results for RV fractional area change (FAC), RVGS, and RVFWS. Dividing the population into two-groups based on RVEF, we found 14 patients with RV dysfunction (27.4%), and significant differences between the groups for all RV function variables. For detection of RV dysfunction defined by 3DE, ROC curve analysis showed the best area under the curve (AUC) for RVGS (0.872), RVFWS (0.851) and FAC (0.932). Conclusions: We observed significant correlation between RVGS, RVFWS and RVEF, with good accuracy in detecting RV dysfunction, comparable to FAC and better than other conventional parameters of RV function assessment. The evaluation of RV myocardial deformation with 2DS may have additional diagnostic and prognostic value in patients with severe left-sided VHD. (Int J Cardiovasc Sci. 2018; [online].ahead print, PP.0-0).
DOI: 10.6084/m9.figshare.7518257
title: Qualitative management of water resources. Proposed methodology for planning a stations network for monitoring the quality of surface water. Case study: basin Muriaé River.

description: ABSTRACT Among the premises for planning a water quality monitoring network is understanding of the regional geographic, hydrological and economic conditions. In this context, this article describes the planning of a water quality monitoring network for the Muriaé River Basin, so that based on the technical criteria adopted, the positioning of the stations meets the monitoring needs. The Muriaé River, a tributary on the left bank of the Paraíba do Sul River, has a watershed of 8,161 km2. The leading economic activities in this area are manufacturing, concentrated in two industrial clusters in the municipalities of Muriaé (Minas Gerais state) and Itaperuna (Rio de Janeiro state), and agriculture, mainly along the Gavião River and near the discharge of the basin. Regarding hydropower generation, there are no power plants with inundated areas greater than 3 km2, the lower threshold for required monitoring according to Resolution 003/2010 issued jointly by the National Water Agency and National Electric Energy Agency. Finally, monitoring points were projected following the criteria for control or strategic points, reference points, impact points and potential power generation points. A Water Quality Index (WQI) was calculated to identify the points with water stress in the basin. The scales defined were hydrography of 1:250,000, Otto codification at level 6 and distribution of discharge of organic waste by urban districts. The results indicate that the location of the stations tends to approximate the potential points of pollution in the basin.
DOI: 10.6084/m9.figshare.7518257.v1
title: Qualitative management of water resources. Proposed methodology for planning a stations network for monitoring the quality of surface water. Case study: basin Muriaé River.

description: ABSTRACT Among the premises for planning a water quality monitoring network is understanding of the regional geographic, hydrological and economic conditions. In this context, this article describes the planning of a water quality monitoring network for the Muriaé River Basin, so that based on the technical criteria adopted, the positioning of the stations meets the monitoring needs. The Muriaé River, a tributary on the left bank of the Paraíba do Sul River, has a watershed of 8,161 km2. The leading economic activities in this area are manufacturing, concentrated in two industrial clusters in the municipalities of Muriaé (Minas Gerais state) and Itaperuna (Rio de Janeiro state), and agriculture, mainly along the Gavião River and near the discharge of the basin. Regarding hydropower generation, there are no power plants with inundated areas greater than 3 km2, the lower threshold for required monitoring according to Resolution 003/2010 issued jointly by the National Water Agency and National Electric Energy Agency. Finally, monitoring points were projected following the criteria for control or strategic points, reference points, impact points and potential power generation points. A Water Quality Index (WQI) was calculated to identify the points with water stress in the basin. The scales defined were hydrography of 1:250,000, Otto codification at level 6 and distribution of discharge of organic waste by urban districts. The results indicate that the location of the stations tends to approximate the potential points of pollution in the basin.
DOI: 10.5066/p9bkw4bx
title: Tidal daily discharge and quality assurance data supporting an assessment of water quality and discharge in the Herring River, Wellfleet, Massachusetts, November 2015 &ndash; September 2017
DOI: 10.6084/m9.figshare.10296044
title: THE POLITICAL ECONOMY OF HEALTH IN FRENCH TERRITORY AND THE GLOBALIZED PHARMACEUTICAL MANUFACTURING

description: ABSTRACT We approach the production of biomedicines in France as a productive spatial circuit. This circuit is part of the health-industrial complex (HIC), a concept that helps to explain the spatial and historical context to analyze the political economy of health care in France. Initially, we justify the use of the concept of the health-industrial complex, rather than the medical-industrial complex, as is commonly used in France and in Anglo-Saxon countries, and its relation to the political economy of health care. Then, we explain why the productive spatial circuit is more appropriate to a geographic approach of this industrial complex than the productive chain. Finally, we deal with the production of biomedicines and, more specifically, the importance of the Contract Development and Manufacturing Organization (CDMO) in the production of this technology to serve the major pharmaceutical laboratories, favoring the global production of this industrial branch.
DOI: 10.6084/m9.figshare.10296044.v1
title: THE POLITICAL ECONOMY OF HEALTH IN FRENCH TERRITORY AND THE GLOBALIZED PHARMACEUTICAL MANUFACTURING

description: ABSTRACT We approach the production of biomedicines in France as a productive spatial circuit. This circuit is part of the health-industrial complex (HIC), a concept that helps to explain the spatial and historical context to analyze the political economy of health care in France. Initially, we justify the use of the concept of the health-industrial complex, rather than the medical-industrial complex, as is commonly used in France and in Anglo-Saxon countries, and its relation to the political economy of health care. Then, we explain why the productive spatial circuit is more appropriate to a geographic approach of this industrial complex than the productive chain. Finally, we deal with the production of biomedicines and, more specifically, the importance of the Contract Development and Manufacturing Organization (CDMO) in the production of this technology to serve the major pharmaceutical laboratories, favoring the global production of this industrial branch.
DOI: 10.6084/m9.figshare.5816226
title: Hydrodynamics of a tropical estuary: Buranhém River, Porto Seguro, Brazil

description: ABSTRACT Estuaries are dynamic environments that are highly vulnerable to anthropogenic influences, especially when adjacent to urban areas. In this study it is assessed for the first time the hydrodynamic characteristics of the Buranhém estuary (Northeast Brazil). The aim is to define the salt transport mechanisms and the hydrodynamics and stratification patterns of this tropical estuary, under both spring and neap tidal conditions. Fieldwork was carried out during 8 days covering varying tidal range conditions (July 30th to August 7th, 2015). Salinity and temperature were continuously monitored at moored stations at both the surface and bottom, whereas velocity profile was sampled by a bottom-mounted instrument. Average velocity in the water column was 0.46 m.s-1 during flood tides and 1.0 m.s-1 during ebb tides. Residual currents were seaward, with ebb dominance. The dominant salt transport mechanism is turbulent diffusion. Most of the layer Richardson values did not exceed 2, indicating well mixed conditions mainly during spring tides. Stratification varies with tide condition, with spring tides being able to further mix the vertical structure. Vertical velocity gradients that generate vertical mixing overcome the stabilizing effects generated by vertical density gradients.
DOI: 10.6084/m9.figshare.7509026
title: Knock on the Right Door. How we are Treating the Patient with Acute Myocardial Infarction

description: Abstract Background: To reduce mortality of acute myocardial infarction, medical care must be provided within the first hours of the event. Objective: To identify the “front door” to medical care of acute coronary patients and the time elapsed between patients’ admission and performance of myocardial reperfusion in the public health system of the city of Joinville, Brazil. Methods: The study was a retrospective analysis of the medical records of 112 consecutive patients diagnosed with acute myocardial infarction by coronary angiography. We identified the place of the first medical contact and calculated the time between admission to this place and admission to the referral hospital, as well as the time until coronary angiography, with or without percutaneous transluminal angioplasty. A descriptive analysis of data was made using mean and standard deviation, and a p &lt; 0.05 was set as statistically significant. Results: Only 16 (14.3%) patients were admitted through the cardiology referral unit. Door-to-angiography time was shorter than 90 minutes in 50 (44.2%) patients and longer than 270 minutes in 39 (34.5%) patients. No statistically significant difference was observed in door-to-angiography time between patients transported directly to the referral hospital and those transferred from other health units (p&lt;0.240). Considering the time between pain onset and angiography, only 3 (2.9%) patients may have benefited from myocardial reperfusion performed within less than 240 minutes. Conclusion: Management of patients with acute myocardial infarction is not in conformity with current guidelines for the treatment of this condition. The structure of the healthcare system should be urgently modified so that users in need of emergency services receive adequate care in accordance with local conditions.
DOI: 10.6084/m9.figshare.7509026.v1
title: Knock on the Right Door. How we are Treating the Patient with Acute Myocardial Infarction

description: Abstract Background: To reduce mortality of acute myocardial infarction, medical care must be provided within the first hours of the event. Objective: To identify the “front door” to medical care of acute coronary patients and the time elapsed between patients’ admission and performance of myocardial reperfusion in the public health system of the city of Joinville, Brazil. Methods: The study was a retrospective analysis of the medical records of 112 consecutive patients diagnosed with acute myocardial infarction by coronary angiography. We identified the place of the first medical contact and calculated the time between admission to this place and admission to the referral hospital, as well as the time until coronary angiography, with or without percutaneous transluminal angioplasty. A descriptive analysis of data was made using mean and standard deviation, and a p &lt; 0.05 was set as statistically significant. Results: Only 16 (14.3%) patients were admitted through the cardiology referral unit. Door-to-angiography time was shorter than 90 minutes in 50 (44.2%) patients and longer than 270 minutes in 39 (34.5%) patients. No statistically significant difference was observed in door-to-angiography time between patients transported directly to the referral hospital and those transferred from other health units (p&lt;0.240). Considering the time between pain onset and angiography, only 3 (2.9%) patients may have benefited from myocardial reperfusion performed within less than 240 minutes. Conclusion: Management of patients with acute myocardial infarction is not in conformity with current guidelines for the treatment of this condition. The structure of the healthcare system should be urgently modified so that users in need of emergency services receive adequate care in accordance with local conditions.
DOI: 10.6084/m9.figshare.7512650
title: Research on calcifications in the cervical region using panoramic and teleradiographic techniques

description: ABSTRACT Objective: The aim of the study was to evaluate the contribution of lateral and frontal teleradiographs to the identification and location of calcifications in soft tissues, when compared with those observed in panoramic radiographs. Methods: Radiopaque references in gutta-percha were placed unilaterally on the heads of three cadavers, endeavoring at all times to keep to the same level as the bifurcation of the common carotid artery in different structures, sites of possible calcifications, and three radiographic incidences were obtained for each anatomic part. Thus, the sample of this study was composed of 27 panoramic radiographs, 27 lateral teleradiographs and 27 frontal teleradiographs, totaling 81 radiographs. Results: According to the criteria of Cicchetti and Sparrow, the intraclass correlation coefficients (ICCs) obtained were below 0.40. Conclusion: It can be concluded that the lateral and frontal teleradiographs did not contribute efficiently to the identification and location of radiopacities in the cervical region, and that the anatomic conformation interferes in the observation of the presence of radiopacity in the cervical region.
DOI: 10.6084/m9.figshare.7512650.v1
title: Research on calcifications in the cervical region using panoramic and teleradiographic techniques

description: ABSTRACT Objective: The aim of the study was to evaluate the contribution of lateral and frontal teleradiographs to the identification and location of calcifications in soft tissues, when compared with those observed in panoramic radiographs. Methods: Radiopaque references in gutta-percha were placed unilaterally on the heads of three cadavers, endeavoring at all times to keep to the same level as the bifurcation of the common carotid artery in different structures, sites of possible calcifications, and three radiographic incidences were obtained for each anatomic part. Thus, the sample of this study was composed of 27 panoramic radiographs, 27 lateral teleradiographs and 27 frontal teleradiographs, totaling 81 radiographs. Results: According to the criteria of Cicchetti and Sparrow, the intraclass correlation coefficients (ICCs) obtained were below 0.40. Conclusion: It can be concluded that the lateral and frontal teleradiographs did not contribute efficiently to the identification and location of radiopacities in the cervical region, and that the anatomic conformation interferes in the observation of the presence of radiopacity in the cervical region.
DOI: 10.6084/m9.figshare.7512740
title: EDUCATIONAL POLICIES OF LIBERAL GOVERNMENTS IN THE CREATION AND ORGANIZATION OF THE NORMAL SCHOOLS OF BOYACA (1930-1938)

description: Abstract At the beginning of the 20th century, most of Boyacá’s population was in the rural areas becoming this department in a pioneer for building schools and improving the teacher’s work conditions; as part of this, new Normal schools were opened, which allowed to train new teachers between 1930 and 1938. Taking it into account, 4 key central concepts were formulated to develop this research project: National educational policies implemented in the Colombian Normal Schools, the implementation of these educational reforms in the department of Boyacá, the teacher’s training, curriculum implemented in these institutions and the schooling processes developed during the study period. The following question was considered: How did the educational policies of liberalism influence on the creation and organization of Normal schools in Boyacá? It is supported by the social history method of education; for the data collection and analysis of sources such as: memoirs of education ministers of that time, secretaries of education and newspapers, the hermeneutical approach methodology was used.
DOI: 10.6084/m9.figshare.7512740.v1
title: EDUCATIONAL POLICIES OF LIBERAL GOVERNMENTS IN THE CREATION AND ORGANIZATION OF THE NORMAL SCHOOLS OF BOYACA (1930-1938)

description: Abstract At the beginning of the 20th century, most of Boyacá’s population was in the rural areas becoming this department in a pioneer for building schools and improving the teacher’s work conditions; as part of this, new Normal schools were opened, which allowed to train new teachers between 1930 and 1938. Taking it into account, 4 key central concepts were formulated to develop this research project: National educational policies implemented in the Colombian Normal Schools, the implementation of these educational reforms in the department of Boyacá, the teacher’s training, curriculum implemented in these institutions and the schooling processes developed during the study period. The following question was considered: How did the educational policies of liberalism influence on the creation and organization of Normal schools in Boyacá? It is supported by the social history method of education; for the data collection and analysis of sources such as: memoirs of education ministers of that time, secretaries of education and newspapers, the hermeneutical approach methodology was used.
DOI: 10.6084/m9.figshare.7512119
title: Use of Moringa oleifera seeds for the removal of turbidity of water supply

description: Water used for human consumption may contain various impurities and solid particles in suspension that increase its turbidity level. Moringa oleifera Lam is a plant that has the potential to be used as coagulating agent in removing turbidity. The objective of this work was to evaluate the efficiency of Moringa oleifera seeds used in shells and without shells in the removal of turbidity from waters with different degrees of turbidity. Waters were used with 70, 250 and 400 initial NTU obtained synthetically. The extract of moringa seeds was prepared using unshelled and shelled seeds, seeking a simplified procedure and practice. The sedimentation times and dose of coagulant solution used were based on existing recommendations in the literature. All treatments were performed with three replicates and the averages depicted in graphs. The results showed that the use of extract of moringa seeds in shells was more efficient than with unshelled seeds in the removal of turbidity of all treatments and that the shelled seeds removed more than 99% of the initial turbidity of the water samples. Furthermore, there was a direct relationship between turbidity removal efficiency and the level of initial turbidity of the samples. The seeds were more efficient in removing turbidity of the water with a higher level of initial turbidity.
DOI: 10.6084/m9.figshare.7512119.v1
title: Use of Moringa oleifera seeds for the removal of turbidity of water supply

description: Water used for human consumption may contain various impurities and solid particles in suspension that increase its turbidity level. Moringa oleifera Lam is a plant that has the potential to be used as coagulating agent in removing turbidity. The objective of this work was to evaluate the efficiency of Moringa oleifera seeds used in shells and without shells in the removal of turbidity from waters with different degrees of turbidity. Waters were used with 70, 250 and 400 initial NTU obtained synthetically. The extract of moringa seeds was prepared using unshelled and shelled seeds, seeking a simplified procedure and practice. The sedimentation times and dose of coagulant solution used were based on existing recommendations in the literature. All treatments were performed with three replicates and the averages depicted in graphs. The results showed that the use of extract of moringa seeds in shells was more efficient than with unshelled seeds in the removal of turbidity of all treatments and that the shelled seeds removed more than 99% of the initial turbidity of the water samples. Furthermore, there was a direct relationship between turbidity removal efficiency and the level of initial turbidity of the samples. The seeds were more efficient in removing turbidity of the water with a higher level of initial turbidity.
DOI: 10.6084/m9.figshare.14269994.v1
title: Main Study (Responses).xlsx

description: This study aims to evaluate the predictive relationship of attitudes, subjective norms, perceived behavioural control and willingness to buy grocery online.
DOI: 10.6084/m9.figshare.14269994
title: Main Study (Responses).xlsx

description: This study aims to evaluate the predictive relationship of attitudes, subjective norms, perceived behavioural control and willingness to buy grocery online.
DOI: 10.6084/m9.figshare.13286031
title: Effects of adjunct treatment with intravenous immunoglobulins on the course of severe COVID-19: results from a retrospective cohort study

description: To evaluate the effect of adjunct treatment with Octagam, an intravenous immunoglobulin (IVIG) product, on clinical outcomes and biomarkers in critically ill COVID-19 patients. Data from a single center was analyzed retrospectively. Patients had received preliminary standard intensive care (SIC) according to a local treatment algorithm, either alone or along with IVIG 5% at 30 g/day for 5 days. The two groups were compared regarding baseline characteristics, survival and changes in inflammation markers. Imbalance in baseline APACHE II scores was addressed by propensity score matching. Otherwise, Kaplan–Meier and multiple logistic regression models were used. Out of 93 patients, 51 had received IVIG and 42 had not. About 75% of patients were male and both groups had comparable body mass index and AB0 blood type distribution. IVIG-treated patients were younger (mean 65 ± 15 versus 71 ± 15 years, <i>p</i> = .066) and had slightly lower baseline disease scores (APACHE II: 20.6 versus 22.4, <i>p</i> = .281; SOFA: 5.0 versus 7.0, <i>p</i> = .006). Overall survival was 61% in the SIC + IVIG and 38% in the SIC only group (odds ratio: 2.2, 95% confidence interval: 0.9–5.4, <i>p</i> = .091 after controlling for baseline imbalances). IVIG significantly prolonged median survival time (68 versus 18 days, <i>p</i> = .014) and significantly reduced plasma levels of C-reactive protein (median change from baseline −71.5 versus −0.3 mg/L, <i>p</i> = .049). Clinically relevant benefits through adjunct IVIG treatment in COVID-19 need to be confirmed in a randomized, controlled trial.