cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17632/dn8khn4c6w
title: Pharmacological Network Analysis to Explore the Functions and Mechanisms Underlying the Effect of Quercetin from Achyranthis Bidentatae Radix on Intervertebral Disc Degeneration

description: Intervertebral disc degeneration (IDD) is a common multifactorial disorder in orthopedics and a leading cause of low-back pain. Achyranthis Bidentatae Radix (ABR) and its active components have been applied in clinical treatments for IDD. This study aimed to explore the therapeutic effects and the underlying mechanisms of ABR in treating IDD. Network pharmacology, RNA sequencing (RNA seq), molecular docking, and molecular dynamics simulation were employed to predict potential ABR targets for IDD treatment. An in vitro IDD model was established using IL-1β–treated nucleus pulposus cells (NPCs). To explore the biological processes and signaling pathways, we employed toluidine blue staining, β-Gal senescence staining, CCK-8 assay, TUNEL apoptosis assay, reactive oxygen species (ROS) detection, flow cytometry, RT-qPCR, and western blotting. Network pharmacology and RNA-seq confirmed 30 overlapping hub genes. Functional enrichment annotation showed their significant involvement in hypoxia, collagen biosynthetic, inflammatory response, angiogenesis, and PI3K-Akt signaling pathway. Protein-protein interaction (PPI) analysis, molecular docking and molecular dynamics simulations revealed that quercetin (QUE), a major active component of ABR, exhibits strong binding affinity to the core target NOS3 (eNOS). In vitro experiments demonstrated that QUE significantly improved NPCs viability and reduced oxidative stress, extracellular matrix (ECM) degradation, inflammatory responses, apoptosis, and cellular senescence induced by IL-1β. Furthermore, QUE inhibited phosphorylation of p-PI3K, p-Akt, and p-NOS3 in IDD progression. Our results suggest that QUE protects NPCs from IL-1β–induced injury by regulating NPC viability, oxidative stress, ECM degradation, inflammatory responses, apoptosis, and cellular senescence. The PI3K/Akt/eNOS signaling pathway may play a critical role in this process.
DOI: 10.17632/dn8khn4c6w.1
title: Pharmacological Network Analysis to Explore the Functions and Mechanisms Underlying the Effect of Quercetin from Achyranthis Bidentatae Radix on Intervertebral Disc Degeneration

description: Intervertebral disc degeneration (IDD) is a common multifactorial disorder in orthopedics and a leading cause of low-back pain. Achyranthis Bidentatae Radix (ABR) and its active components have been applied in clinical treatments for IDD. This study aimed to explore the therapeutic effects and the underlying mechanisms of ABR in treating IDD. Network pharmacology, RNA sequencing (RNA seq), molecular docking, and molecular dynamics simulation were employed to predict potential ABR targets for IDD treatment. An in vitro IDD model was established using IL-1β–treated nucleus pulposus cells (NPCs). To explore the biological processes and signaling pathways, we employed toluidine blue staining, β-Gal senescence staining, CCK-8 assay, TUNEL apoptosis assay, reactive oxygen species (ROS) detection, flow cytometry, RT-qPCR, and western blotting. Network pharmacology and RNA-seq confirmed 30 overlapping hub genes. Functional enrichment annotation showed their significant involvement in hypoxia, collagen biosynthetic, inflammatory response, angiogenesis, and PI3K-Akt signaling pathway. Protein-protein interaction (PPI) analysis, molecular docking and molecular dynamics simulations revealed that quercetin (QUE), a major active component of ABR, exhibits strong binding affinity to the core target NOS3 (eNOS). In vitro experiments demonstrated that QUE significantly improved NPCs viability and reduced oxidative stress, extracellular matrix (ECM) degradation, inflammatory responses, apoptosis, and cellular senescence induced by IL-1β. Furthermore, QUE inhibited phosphorylation of p-PI3K, p-Akt, and p-NOS3 in IDD progression. Our results suggest that QUE protects NPCs from IL-1β–induced injury by regulating NPC viability, oxidative stress, ECM degradation, inflammatory responses, apoptosis, and cellular senescence. The PI3K/Akt/eNOS signaling pathway may play a critical role in this process.
DOI: 10.17632/t53k6b8ghg
title: The vitality of regional development

description: The vitality of regional development
DOI: 10.17632/rb3cffgpzj
title: Assessment of the implementation of BIM and DT in Water Management Sector: A case study of luanda,Angola

description: This dataset was obtained from a field survey conducted in the Luanda-Angola. The dataset, collected between from March 14 to October 04, 2024 using a a non-probability expert sampling framework, to evaluates the adoption of BIM and DT technologies in the Luanda water sector. The survey link was self-administered questionnaires distributed through two primary channels: institutional partnerships with OEA and OA headquarters in Luanda, and targeted outreach to AECO firms identified via Angolan industry registries, resulting in 63 complete responses during the study period. A rigorous multi-stage analytical framework to examine BIM and DT adoption patterns in Angola's water sector. Chi-Square statistical analyses were conducted at a 0.05 significance threshold using Statistical Package for the Social Sciences (SPSS) software.
Results revealed that BIM familiarity varies significantly across professionals and that most have a basic understanding of the DT. Results also reveal that improved planning and design processes emerged as principal benefits, followed by enhanced data management and better visualization and simulation capabilities. 
Keywords: BIM implementation; Digital Twin; Water Management; Angola
DOI: 10.17632/t53k6b8ghg.1
title: The vitality of regional development

description: The vitality of regional development
DOI: 10.17632/gm95hsn33d
title: Building data of a Industrial Parks in Southern China

description: This dataset comprises vector data of industrial buildings within an industrial development zone in Zhangzhou City, Fujian Province, China. It includes building height, rooftop obstructions, rooftop radiation, rooftop material, corresponding industrial enterprise information, production environment, and rooftop solar potential scores.
DOI: 10.17632/rb3cffgpzj.1
title: Assessment of the implementation of BIM and DT in Water Management Sector: A case study of luanda,Angola

description: This dataset was obtained from a field survey conducted in the Luanda-Angola. The dataset, collected between from March 14 to October 04, 2024 using a a non-probability expert sampling framework, to evaluates the adoption of BIM and DT technologies in the Luanda water sector. The survey link was self-administered questionnaires distributed through two primary channels: institutional partnerships with OEA and OA headquarters in Luanda, and targeted outreach to AECO firms identified via Angolan industry registries, resulting in 63 complete responses during the study period. A rigorous multi-stage analytical framework to examine BIM and DT adoption patterns in Angola's water sector. Chi-Square statistical analyses were conducted at a 0.05 significance threshold using Statistical Package for the Social Sciences (SPSS) software.
Results revealed that BIM familiarity varies significantly across professionals and that most have a basic understanding of the DT. Results also reveal that improved planning and design processes emerged as principal benefits, followed by enhanced data management and better visualization and simulation capabilities. 
Keywords: BIM implementation; Digital Twin; Water Management; Angola
DOI: 10.17632/gm95hsn33d.1
title: Building data of a Industrial Parks in Southern China

description: This dataset comprises vector data of industrial buildings within an industrial development zone in Zhangzhou City, Fujian Province, China. It includes building height, rooftop obstructions, rooftop radiation, rooftop material, corresponding industrial enterprise information, production environment, and rooftop solar potential scores.
DOI: 10.15468/ev5veg
title: Cryptic or underworked? Taxonomic revision of the Antistrophus rufus species complex (Cynipoidea, Aulacideini)

description: This dataset contains the digitized treatments in Plazi based on the original journal article Nastasi, Louis F., Tooker, John F., Davis, Charles K., Smith, Cecil N., Frey, Timothy S., Hatfield, M. J., Presnall, Tara M., Hines, Heather M., Deans, Andrew R. (2024): Cryptic or underworked? Taxonomic revision of the Antistrophus rufus species complex (Cynipoidea, Aulacideini). Journal of Hymenoptera Research 97: 399-439, DOI: 10.3897/jhr.97.121918AbstractCryptic species present challenges across many subdisciplines of biology. Not all “ cryptic ” species, however, are truly cryptic; many are simply underexplored morphologically. We examined this idea for the Antistrophus rufus species complex, which previously contained three species thought to be morphologically cryptic. To determine whether the A. rufus complex are truly cryptic species, we assessed species boundaries of members of the A. rufus species complex using morphological, ecological, and DNA barcode data, and tested whether a set of 50 morphological characters could adequately diagnose these species. We revealed that this complex includes five species, and that there are useful phenotypic diagnostic characters for all members of this species complex. This enabled redescription of four species and the description of Antistrophus laurenae Nastasi, sp. nov., which induces externally inconspicuous galls in stems of Silphium integrifolium Michx., a host not associated with other members of the complex. We use these new diagnostic characters to construct a key to the five species of the rufus complex. We conclude that the A. rufus complex was not a true case of cryptic species. Our Bayesian analysis of DNA barcode data suggests possible cospeciation of members of the rufus complex and their Silphium host plants, but further study is necessary to better understand the evolution of host use in the lineage.
DOI: 10.5281/zenodo.14326528
title: Seismo-tectonics of Greater Iberia: An updated review

description: Present databases are results of the article Seismo-tectonics of Greater Iberia: An updated review. 

Authors:Olaiz, A., Álvarez Gómez, J.A., De Vicente, G., Muñoz-Martín, A., Cantavella, J.V., Custódio, S., Vales, D. and Heidbach, O.

Current status: under review in Solid Earth

The file focal mechanism is a compilation of the moment tensor focal mechanisms in Iberia. It contains 472 events, including 9 new focal mechanisms. 

The World Stress Map database is an updated version of the last database published in 2016. The focal mechanisms have been added and categorized according to WSM quality standards.
DOI: 10.5281/zenodo.14609801
title: Seismo-tectonics of Greater Iberia: An updated review

description: Present databases are results of the article Seismo-tectonics of Greater Iberia: An updated review. 

Authors:Olaiz, A., Álvarez Gómez, J.A., De Vicente, G., Muñoz-Martín, A., Cantavella, J.V., Custódio, S., Vales, D. and Heidbach, O.

Current status: under review in Solid Earth

The file focal mechanism is a compilation of the moment tensor focal mechanisms in Iberia. It contains 472 events, including 9 new focal mechanisms. 

The World Stress Map database is an updated version of the last database published in 2016. The focal mechanisms have been added and categorized according to WSM quality standards.
DOI: 10.15468/uyubgx
title: Five new species of Synagelides Strand, 1906 from China (Araneae, Salticidae)

description: This dataset contains the digitized treatments in Plazi based on the original journal article Liu, Ke-ke, Zhao, Zi-Yi, Xiao, Yong-hong, Peng, Xian-Jin (2022): Five new species of Synagelides Strand, 1906 from China (Araneae, Salticidae). ZooKeys 1102: 59-82, DOI: http://dx.doi.org/10.3897/zookeys.1102.76800, URL: http://dx.doi.org/10.3897/zookeys.1102.76800
DOI: 10.15468/qvj5sz
title: Two news species of Corallistidae (Porifera; Demospongiae; Tetractinellida) with a first record of Awhiowhio from the Atlantic

description: This dataset contains the digitized treatments in Plazi based on the original journal article Dias, Alan, Kelly, Michelle, Pinheiro, Ulisses (2023): Two news species of Corallistidae (Porifera; Demospongiae; Tetractinellida) with a first record of Awhiowhio from the Atlantic. Zootaxa 5277 (1): 182-192, DOI: 10.11646/zootaxa.5277.1.9, URL: http://dx.doi.org/10.11646/zootaxa.5277.1.9AbstractIn the present study, we describe two new species of Corallistidae from Brazil, comparing them to all valid species of the respective genera. Both are notable Porifera records, with the first specimen of Neophrissospongia Pisera and Lévi, 2002 registered for the Brazilian coast and the first specimen of Awhiowhio Kelly, 2007 registered for the Atlantic Ocean. The specimens were preserved in 80% ethanol and analyzed following classical procedure for Demospongiae, with dissociated spicule mounts, skeletal sections and Scanning Electron Microscopy. Neophrissospongia jorgeorum sp. nov. is differentiated from its congeners by the categories of spicules present, especially the lack of streptasters/amphiasters. Awhiowhio saci sp. nov. is characterized especially by the presence of spiraster-shaped microrhabds and microxeas.
DOI: 10.15468/r5q5nh
title: A reappraisal of the taxonomy and biodiversity of the extant coccolithophore genus Palusphaera (Rhabdosphaeraceae, Prymnesiophyceae)

description: This dataset contains the digitized treatments in Plazi based on the original journal article Archontikis, Odysseas A., Young, Jeremy R. (2021): A reappraisal of the taxonomy and biodiversity of the extant coccolithophore genus Palusphaera (Rhabdosphaeraceae, Prymnesiophyceae). Phycologia 60 (6): 589-602, DOI: 10.1080/00318884.2021.1965758, URL: https://doi.org/10.1080/00318884.2021.1965758ABSTRACTThe genus Palusphaera Lecal-Schlauder emend. R.E. Norris is a distinctive modern coccolithophore that accommodates monomorphic, monothecate coccospheres with one type of spine-bearing heterococcoliths. Having examined a set of scanning electron microscopy images from our collections, we were able to demonstrate that four distinct species of Palusphaera exist in the modern oceans, including the type species Palusphaera vandelii, an informally proposed form, Palusphaera sp. 1 (type robusta) that is herein taxonomically ratified as Palusphaera crosiae sp.nov., and a distinctive morphotype,which is formally described as Palusphaera bownii sp. nov. Biometric analyses and observations on the morphologies of numerous P. vandelii specimens revealed the existence of a further form, and its commonly distinguished coccolith morphotypes are therefore taxonomically separated from Palusphaera vandelii and established as a discrete species, Palusphaera probertii sp. nov.
DOI: 10.15468/dl.evvfc7
title: Occurrence Download

description: A dataset containing 4 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Continent is Asia",
 "Country is Pakistan",
 "OccurrenceStatus is Present",
 "TaxonKey is Capra falconeri",
 "Year 1990-2025"
 ]
}

 The dataset includes 4 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0065585-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/ejf7d4
title: On some Acanthoglossa and Hypomedon species II. Two new species, a new synonymy, and additional records (Coleoptera: Staphylinidae: Paederinae)

description: This dataset contains the digitized treatments in Plazi based on the original journal article Assing, Volker (2016): On some Acanthoglossa and Hypomedon species II. Two new species, a new synonymy, and additional records (Coleoptera: Staphylinidae: Paederinae). Linzer biologische Beiträge 48 (1): 317-325, DOI: 10.5281/zenodo.5416273
DOI: 10.15468/9tm87r
title: A further study on the spider genus Baiyuerius Zhao, Li & Li, 2023, from China (Agelenidae, Coelotinae)

description: This dataset contains the digitized treatments in Plazi based on the original journal article Luo, Bin, Lu, Feng, Zhang, Zhi-Sheng, Wang, Lu-Yu (2023): A further study on the spider genus Baiyuerius Zhao, Li & Li, 2023, from China (Agelenidae, Coelotinae). ZooKeys 1184: 91-102, DOI: http://dx.doi.org/10.3897/zookeys.1184.107931, URL: http://dx.doi.org/10.3897/zookeys.1184.107931
DOI: 10.15468/bdsype
title: A taxonomic review of the Amazonian rheophyte Schusterolejeunea Grolle (Lejeuneaceae: Cololejeuneinae), with two new combinations

description: This dataset contains the digitized treatments in Plazi based on the original journal article Sierra, Adriel M., Zartman, Charles E. (2023): A taxonomic review of the Amazonian rheophyte Schusterolejeunea Grolle (Lejeuneaceae: Cololejeuneinae), with two new combinations. Cryptogamie, Bryologie 20 (4): 107-122, DOI: 10.5252/cryptogamie-bryologie2023v44a4, URL: http://dx.doi.org/10.11646/zootaxa.4878.3.2ABSTRACTSchusterolejeunea inundata (Spruce) Grolle is a widespread, yet poorly known species restricted to riparian habitats of the Amazon Basin in northern South America. Since its original description by Richard Spruce in 1884, phenotypic differences among populations convinced the original author to split the taxon into two varieties. An extensive review of Schusterolejeunea Grolle specimens hailing from disparate regions of the Amazon Basin has provided convincing evidence of discontinuities among leaf, lobule, and perianth morphology offering support for a novel taxonomic proposal. In the present review, the genus Schusterolejeunea encompasses two species, S. inundata and the newly elevated species Schusterolejeunea saxorum (Spruce) A.M.Sierra & C.E.Zartman, stat. nov., comb. nov., which differs from S. inundata by its oblong leaves, with large rectangular to oblong lobules, that cover 1/3-2/3 of the leaf lobe, and the perianth with five indistinct low keels. The variety Schusterolejeunea inundata var. fontinaloides (Spruce) A.M.Sierra & C.E.Zartman, comb. nov. is considered a distinct taxon, distinguished from S. inundata var. inundata by its ovate leaves, and lobules on the primary stem triangular with a longer keel extending 6-12 cells long. For each taxon, we present a detailed morphological description, current geographical distribution, and illustrations.
DOI: 10.15468/eft3a9
title: Info Flora Schweiz - Balsaminaceae

description: This dataset contains the digitized treatments in Plazi based on the original url / website Info Flora (2021): Info Flora Schweiz - Balsaminaceae., URL: https://www.infoflora.ch/de/flora/balsaminaceae.html
DOI: 10.15468/aa5zes
title: Taxonomic and nomenclatural novelties in some Cactaceae of Greater Antilles

description: This dataset contains the digitized treatments in Plazi based on the original journal article Guiggi, Alessandro, Mariotti, Mauro (2022): Taxonomic and nomenclatural novelties in some Cactaceae of Greater Antilles. Phytotaxa 573 (2): 215-230, DOI: 10.11646/phytotaxa.573.2.3, URL: http://dx.doi.org/10.11646/phytotaxa.573.2.3AbstractThe recently debated identity and incertus status of Cereus serruliflorus, Opuntia taylorii, O. tuna. and of its presumed close relatives, O. dillenii and O. jamaicensis from the Caribbean region, are here investigated to clarify the correct application of the names through an analysis of the protologues, original material, and examination of other specimens. One new endemic species to Jamaica (O. kingstoniana) was described; O. repens subsp. taylorii comb. nov. is proposed; an epitipe was designated for Cactus tuna (≡ O. tuna) and Cereus serruliflorus (≡ Serrulatocereus serrulatus); O. jamaicensis is here accepted as a valid species, distinct from O. tuna sensu auct.
DOI: 10.15468/vzawsq
title: Molecular phylogeny and taxonomy of the Hydrangea serrata complex (Hydrangeaceae) in western Japan, including a new subspecies of H. acuminata from Yakushima

description: This dataset contains the digitized treatments in Plazi based on the original journal article Hirota, Shun K., Yahara, Tetsukazu, Fuse, Kengo, Sato, Hiroyuki, Tagane, Shuichiro, Fujii, Shinji, Minamitani, Tadashi, Suyama, Yoshihisa (2022): Molecular phylogeny and taxonomy of the Hydrangea serrata complex (Hydrangeaceae) in western Japan, including a new subspecies of H. acuminata from Yakushima. PhytoKeys 188: 49-71, DOI: http://dx.doi.org/10.3897/phytokeys.188.64259, URL: http://dx.doi.org/10.3897/phytokeys.188.64259
DOI: 10.15468/r7evs6
title: The Vitex trifolia complex (Lamiaceae) in the Philippines

description: This dataset contains the digitized treatments in Plazi based on the original journal article Gentallan Jr., Renerio P., Sengun, Seda, Bartolome, Michael Cedric B., Quiñones, Kristine Joyce O., Coronado, Nadine B., Borromeo, Teresita H., Timog, Emmanuel Bonifacio S. (2024): The Vitex trifolia complex (Lamiaceae) in the Philippines. PhytoKeys 248: 1-40, DOI: 10.3897/phytokeys.248.120387AbstractThe Vitex trifolia complex in the Philippines comprises economically important medicinal species, but its taxonomic status has become ambiguous due to numerous historical nomenclatural revisions. We assembled the complete chloroplast genomes of five species belonging to this species complex to provide additional evidence for their species delimitation. Based on a detailed analysis of specimens which combined molecular and morphological data, we propose reinstating V. elmeri Moldenke and delineating V. arvensis Gentallan, Sengun & M. B. Bartolome as a new endemic species belonging to this complex. The new species is a putative hybrid between V. bicolor Willd. and V. elmeri Moldenke. The specific epithet arvensis reflects its predominantly cultivated nature, both on a commercial scale and in home gardens, as a valued medicinal plant. We also provided a key to identify the five species belonging to the V. trifolia complex in the Philippines.
DOI: 10.15468/shnn5h
title: Typification of names allied to Centaurea ambigua (Asteraceae) from the Apennine Peninsula (Italy)

description: This dataset contains the digitized treatments in Plazi based on the original journal article Bartolucci, Fabrizio, Conti, Fabio (2024): Typification of names allied to Centaurea ambigua (Asteraceae) from the Apennine Peninsula (Italy). Italian Botanist 18: 215-223, DOI: 10.3897/italianbotanist.18.143065AbstractA contribution to the nomenclature of the Italian endemic Centaurea ambigua is presented. A survey of original material for the names applied to the three currently accepted subspecies (C. ambigua subsp. ambigua, C. ambigua subsp. laciniata, C. ambigua subsp. nigra) was performed. Lectotypes for five names based on specimens preserved at FI, G and NAP are designated: C. ambigua, C. dissecta var. macrocephala, C. dissecta var. melanocephala, C. dissecta var. nigra, and C. laciniata. Finally, C. ambigua subsp. laciniata, actually considered a subspecies narrowly endemic to Abruzzo (central Italy), is proposed here as a heterotypic synonym of C. ambigua subsp. ambigua.
DOI: 10.15468/mbh2bk
title: A taxonomic review of the genus Fignya Solovyev & Witt, 2009 (Lepidoptera, Limacodidae) with descriptions of three new species and one new combination

description: This dataset contains the digitized treatments in Plazi based on the original journal article Wu, Jun, Han, Huilin (2024): A taxonomic review of the genus Fignya Solovyev & Witt, 2009 (Lepidoptera, Limacodidae) with descriptions of three new species and one new combination. ZooKeys 1213: 225-235, DOI: 10.3897/zookeys.1213.132318AbstractThree new species of the genus Fignya Solovyev & Witt, 2009, F. qiana sp. nov., F. trigonum sp. nov., and F. samkosa sp. nov., are described from China and Cambodia. Additionally, a new combination, F. brachygnatha (Wu & Fang, 2008), comb. nov., is proposed. The new species are illustrated with images of the adults and male genitalia, and compared with similar species. A key to all known species in the genus, along with their geographical distributions, is provided.