cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.25934/pr00003551.0
title: Available IPD datapackage for study 'Multicenter, Randomized, Double-blind, Phase III Trial to Investigate the Efficacy and Safety of Oral BIBF 1120 Plus Standard Pemetrexed Therapy Compared to Placebo Plus Standard Pemetrexed Therapy in Patients With Stage IIIB/IV or Recurrent Non Small Cell Lung Cancer After Failure of First Line Chemotherapy'

description: The trial will be performed to evaluate if BIBF 1120 in combination with standard pemetrexed therapy is more effective than placebo (inactive capsule) plus standard pemetrexed therapy in patients with stage IIIB, IV or recurrent NSCLC. Safety information about BIBF1120/pemetrexed will be obtained.
DOI: 10.17632/xhhgzjjt3h.1
title: Trichoderma Swollenin protein interacts with AtABCB5 transporter to regulate plant development by activating rapid auxin signaling

description: The datasets registers the trichoderma swollenin protein interacts with AtABCB5 transporter to regulate plant development by activating rapid auxin signaling..30
DOI: 10.17632/dwt6y7nrnx.1
title: Data for Publication

description: Data for Publication in Biocatalysis and Agricultural Biotechnology
DOI: 10.25574/46395
title: Chandra X-ray Observatory ObsId 46395
DOI: 10.25574/46403
title: Chandra X-ray Observatory ObsId 46403
DOI: 10.15468/dl.rc8xb2
title: Occurrence Download

description: A dataset containing 31 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Dama dama",
 "Country is Canada",
 "HasCoordinate is true"
 ]
}

 The dataset includes 31 records from 3 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0015146-250802193616735/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.25574/46404
title: Chandra X-ray Observatory ObsId 46404
DOI: 10.25574/46409
title: Chandra X-ray Observatory ObsId 46409
DOI: 10.25574/46422
title: Chandra X-ray Observatory ObsId 46422
DOI: 10.25574/46426
title: Chandra X-ray Observatory ObsId 46426
DOI: 10.25574/62632
title: Chandra X-ray Observatory ObsId 62632
DOI: 10.25574/62634
title: Chandra X-ray Observatory ObsId 62634
DOI: 10.25574/62644
title: Chandra X-ray Observatory ObsId 62644
DOI: 10.17632/pxw2rbsnv4.1
title: Code and Data for “Breaking Barriers: How Market Competition Sparks Innovation in China's State-Owned Enterprises?”

description: This is a replication package of the paper "Breaking Barriers: How Market Competition Sparks Innovation in China's State-Owned Enterprises?" submitted to Economic Modelling.
DOI: 10.17632/s7wtjxdsvd.2
title: Transcriptomic changes in RAW264.7 cells exposed to bacterial lipopolysaccharide (LPS) and/or the nitrone compound 5,5-dimethyl-1-pyrroline N-oxide (DMPO) - Ilumina Microarray data

description: The main hypothesis to be tested is that DMPO causes transcriptomic changes in macrophages (RAW264.7 cell line) to make them resistant to activation with bacterial lipopolysaccharide (LPS) , chromatographically purified from E. coli 055:B5. 
The main objective was to characterize the overall trasncriptomic changes caused in RAW264.7 cells exposed to DMPO and/or LPS. 
RAW264.7 cells (ATCC TIB-71, passage 3-4) were cultured in T-25 flask in DMEM culture medium with high glucose and 5% heat inactivated fetal calf serum (GIBCO). After reaching a 70% confluence, monolayers were rinsed and incubated in medium alone, medium+DMPO (50mM), medium+LPS (1ng/ml), medium+DMPO+LPS. After incubation for 6h, in 5% CO2 at 37oC, under the 4 different conditions the medium was removed, the mnolayers rinsed with PBS. Following the cell monolayers were harvested in 1ml TRIZOL to purify total RNA. RNA integrity was assessed by capilar electrophoresis (Eukaryote Total RNA Nano). This experiment was repeated in 3 different dates (3 replicates). Transcriptomic analisis was performed by microarray in a Ilumina Platform. 
This data set shows transcriptomic analyses for more than 45000 genes. 
 
The color codes used in the Excel document are:
Medium or Control - pink
Medium + DMPO - yellow
Medium + LPS - green
Medium + DMPO + LPS - orange 



Main conclusions
DMPO by itself causes transcriptomic changes in macrophages. 
LPS activate the expression of genes under the transcriptional control of NF-kB
DMPO dampens LPS-induced transcriptomic changes. 
Remarkably DMPO activates the expression of genes under the transcriptional control of Nrf2.

These data suggest that DMPO can be a potential structural platform for the design of novel kind of mechanism-based anti-inflammatory, antioxidant and poadipogenic drugs for the treatment of chronic inflammatory diseases, in which the phenotypic switch of macrophages from M2 to M1, is the main pathogenic mechanism.
The use of DMPO to block LPS-induced inflammation cytokine storm in sepsis is considered as a life saving therapeutic strategy.
DOI: 10.17632/kpkt95p6by.2
title: Analysis data of organic matter on the debris of glaciers in Mount Gongga

description: Analysis data of organic matter on the debris of glaciers in Mount Gongga”, Mendeley Data
DOI: 10.5517/ccdc.csd.cc2n1ym9
title: CCDC 2444741: Experimental Crystal Structure Determination

description: Related Article: Dongjing Hong|2025|CSD Communication|||
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.17632/y7cgz69654
title: Developing and implementing a self-management skills model for left-behind children in weak rural schools: Using digital technology

description: Data from the daily record sheet, calculated the average time spent by students in each grade on each activity (total time divided by the number of participants), and obtained the average time distribution for Grades 5 and 6.Shown in "Statistics of the Average Duration of Each Activity _ Grade 5 and Statistics of the Average Duration of Each Activity _ Grade 6".
By calculating the average planning rate for each activity (the total number of plans for each activity divided by 60 days), obtained the distribution of average planning rates for students in both grades, as shown in "The average planned rate of each activity _ Grade 5 and The average planned rate of each activity _ Grade 6".
DOI: 10.17632/y7cgz69654.2
title: Developing and implementing a self-management skills model for left-behind children in weak rural schools: Using digital technology

description: Data from the daily record sheet, calculated the average time spent by students in each grade on each activity (total time divided by the number of participants), and obtained the average time distribution for Grades 5 and 6.Shown in "Statistics of the Average Duration of Each Activity _ Grade 5 and Statistics of the Average Duration of Each Activity _ Grade 6".
By calculating the average planning rate for each activity (the total number of plans for each activity divided by 60 days), obtained the distribution of average planning rates for students in both grades, as shown in "The average planned rate of each activity _ Grade 5 and The average planned rate of each activity _ Grade 6".
DOI: 10.17632/gxz97bz82m.1
title: Replication file for common institutional ownership and firms' ESG disclosure

description: Replication file for common institutional ownership and firms' ESG disclosure
DOI: 10.17632/zd8crfzfs8
title: Research data for the research titled, "Hand-Held Laser Welding of Grade-2 Titanium: Effects of Enhanced Shielding on Fractography, Microstructure, and Mechanical Properties"

description: This is research data for the research titled, "Hand-Held Laser Welding of Grade-2 Titanium: Effects of Enhanced Shielding on Fractography, Microstructure, and Mechanical Properties".
DOI: 10.17632/zd8crfzfs8.1
title: Research data for the research titled, "Hand-Held Laser Welding of Grade-2 Titanium: Effects of Enhanced Shielding on Fractography, Microstructure, and Mechanical Properties"

description: This is research data for the research titled, "Hand-Held Laser Welding of Grade-2 Titanium: Effects of Enhanced Shielding on Fractography, Microstructure, and Mechanical Properties".
DOI: 10.15468/dl.scxnaa
title: Occurrence Download

description: A dataset containing 6 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Dama dama",
 "Country is Chile",
 "HasCoordinate is true"
 ]
}

 The dataset includes 6 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0015147-250802193616735/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.17632/fbv4tx873j
title: Enterococcus faecalis YN771

description: This study elucidates the effects of different oxygen concentrations on Enterococcus faecalis YN771 and its oxygen adaptation mechanisms through integrated transcriptomic and metabolomic analyses. Figure 1 presents scanning electron microscopy images of E. faecalis YN771 under varying oxygen levels, demonstrating the impact of oxygen concentration on cellular growth and morphology. Figure 2 displays mass spectrometry analysis of microaerobic samples, while Table 2's gas chromatography results indicate that oxygen concentration variations lead to significant changes in individual fatty acid components.
Transcriptional changes were identified through comparative analysis of YN771's complete transcriptome under different oxygen conditions. Principal component analysis (PCA) revealed distinct transcriptomic differences (Figure 3A), with Figure 3B providing a visual comparison of differentially expressed gene (DEG) numbers across oxygen conditions. GO enrichment analysis showed that during the transition from anaerobic to microaerobic conditions (Figure 4A), DEGs were primarily involved in fatty acid biosynthesis and metabolism. The shift from microaerobic to aerobic culture (Figure 4B) revealed differential gene expression related to cell structure formation (particularly extracellular components and cell walls), morphology regulation, lipid metabolism, and growth-related compound synthesis.

Compared to anaerobic and aerobic groups, significant gene expression differences (Figure 4C) were associated with aerobic energy metabolism, macromolecule (protein, lipid, nucleic acid) synthesis, sulfur metabolism, and oxidative stress adaptation. The anaerobic-to-aerobic transition (Figure 4D) involved differential gene functions in carbon utilization, energy metabolism, macromolecule synthesis, sulfur metabolism, and oxidative stress adaptation.
KEGG analysis demonstrated oxygen-dependent metabolic regulation, showing:
- Aerobic vs. microaerobic conditions (Figure 5A): energy metabolism remodeling, carbon utilization optimization, coenzyme synthesis
- Microaerobic vs. anaerobic (Figure 5B): membrane structure optimization, energy adjustment, cofactor synthesis
- Aerobic vs. anaerobic (Figure 5C): enhanced aerobic respiration, efficient carbon use
- Aerobic vs. microaerobic (Figure 5D): redox balance strengthening, metabolic enhancement
Multivariate analysis confirmed significant aerobic/anaerobic differences (PCA in Figure 6A, OPLS-DA in Figure 6B). Anaerobic condition metabolites showed distinct regulation patterns (Figure 7, Tables 3-4). KEGG pathway analysis (Figure 8A-B) identified 13 significantly altered secondary pathways, primarily in metabolism categories.
Integration of transcriptomic and metabolomic data revealed 12 core metabolic pathways (Table 5). RT-qPCR validation (Figure 9) confirmed consistent expression patterns of virulence factors and metabolic enzymes across oxygen conditions, supporting transcriptome reliability.
DOI: 10.17632/fbv4tx873j.1
title: Enterococcus faecalis YN771

description: This study elucidates the effects of different oxygen concentrations on Enterococcus faecalis YN771 and its oxygen adaptation mechanisms through integrated transcriptomic and metabolomic analyses. Figure 1 presents scanning electron microscopy images of E. faecalis YN771 under varying oxygen levels, demonstrating the impact of oxygen concentration on cellular growth and morphology. Figure 2 displays mass spectrometry analysis of microaerobic samples, while Table 2's gas chromatography results indicate that oxygen concentration variations lead to significant changes in individual fatty acid components.
Transcriptional changes were identified through comparative analysis of YN771's complete transcriptome under different oxygen conditions. Principal component analysis (PCA) revealed distinct transcriptomic differences (Figure 3A), with Figure 3B providing a visual comparison of differentially expressed gene (DEG) numbers across oxygen conditions. GO enrichment analysis showed that during the transition from anaerobic to microaerobic conditions (Figure 4A), DEGs were primarily involved in fatty acid biosynthesis and metabolism. The shift from microaerobic to aerobic culture (Figure 4B) revealed differential gene expression related to cell structure formation (particularly extracellular components and cell walls), morphology regulation, lipid metabolism, and growth-related compound synthesis.

Compared to anaerobic and aerobic groups, significant gene expression differences (Figure 4C) were associated with aerobic energy metabolism, macromolecule (protein, lipid, nucleic acid) synthesis, sulfur metabolism, and oxidative stress adaptation. The anaerobic-to-aerobic transition (Figure 4D) involved differential gene functions in carbon utilization, energy metabolism, macromolecule synthesis, sulfur metabolism, and oxidative stress adaptation.
KEGG analysis demonstrated oxygen-dependent metabolic regulation, showing:
- Aerobic vs. microaerobic conditions (Figure 5A): energy metabolism remodeling, carbon utilization optimization, coenzyme synthesis
- Microaerobic vs. anaerobic (Figure 5B): membrane structure optimization, energy adjustment, cofactor synthesis
- Aerobic vs. anaerobic (Figure 5C): enhanced aerobic respiration, efficient carbon use
- Aerobic vs. microaerobic (Figure 5D): redox balance strengthening, metabolic enhancement
Multivariate analysis confirmed significant aerobic/anaerobic differences (PCA in Figure 6A, OPLS-DA in Figure 6B). Anaerobic condition metabolites showed distinct regulation patterns (Figure 7, Tables 3-4). KEGG pathway analysis (Figure 8A-B) identified 13 significantly altered secondary pathways, primarily in metabolism categories.
Integration of transcriptomic and metabolomic data revealed 12 core metabolic pathways (Table 5). RT-qPCR validation (Figure 9) confirmed consistent expression patterns of virulence factors and metabolic enzymes across oxygen conditions, supporting transcriptome reliability.
DOI: 10.15468/dl.cgu97p
title: Occurrence Download

description: A dataset containing 10 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Paracrossochilus acerus)",
 "BasisOfRecord is one of (Specimen, Literature Occurrence, Human Observation, Observation)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "Year is greater than or equal to 1991",
 "Year is less than or equal to 2025"
 ]
}

 The dataset includes 10 records from 4 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0015149-250802193616735/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.57745/xy3v3h
title: 2009-EGG-RU-0101-Unikauskas.ogg

description: Enregistrement audio en version originale russe
DOI: 10.57745/iyga6f
title: Unikauskas 2-2.avi

description: Enregistrement vidéo, partie 2,
Entretien en russe
DOI: 10.57745/vwrbzx
title: Unikauskas 1-2.avi

description: Enregistrement vidéo, partie 1,
Entretien en russe
DOI: 10.57745/qkpuzu
title: Entretien avec Oleg Unikauskas. Histoire de vie et expériences de déportation en URSS

description: Cet entretien a eu lieu le 16 février 2009 à Bratsk (région d'Irkoutsk), Russie. Il a été mené par Emilia Koustova et Larissa Salakhova, avec la participation de Alain Blum qui s'occupait de l'enregistrement. L'entretien a été réalisé en russe. Il a duré 1 heure et 40 minutes.
DOI: 10.15468/dl.2rqsv8
title: Occurrence Download

description: A dataset containing 14244 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Myrmophylax atrothorax)",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 "License is one of (CC-BY 4.0, CC0 1.0)"
 ]
}

 The dataset includes 14244 records from 13 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0015150-250802193616735/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.nbt492
title: Occurrence Download

description: A dataset containing 101 species occurrences available in GBIF matching the query:
{
 "and" : [
 "OccurrenceStatus is Present",
 "TaxonKey is Pupalia grandiflora"
 ]
}

 The dataset includes 101 records from 12 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0015152-250802193616735/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.eywczx
title: Occurrence Download

description: A dataset containing 320 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Entomacrodus thalassinus"
 ]
}

 The dataset includes 320 records from 33 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0015151-250802193616735/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.17632/6cx8rcftjk
title: Organic Fertilization Optimizes Root Exudates to Strengthen Rhizosphere Microbial Network Stability and Nutrient Cycling in Jackfruit Monoculture System

description: This is a set of data regarding the metabolite components of root systems under different fertilization treatments, the soil microorganisms after metabolite addition, and the soil physical and chemical data.
DOI: 10.17632/6cx8rcftjk.1
title: Organic Fertilization Optimizes Root Exudates to Strengthen Rhizosphere Microbial Network Stability and Nutrient Cycling in Jackfruit Monoculture System

description: This is a set of data regarding the metabolite components of root systems under different fertilization treatments, the soil microorganisms after metabolite addition, and the soil physical and chemical data.
DOI: 10.17632/8xbbck45tt
title: Triple-Wavelength Photoplethysmography for Hemoglobin Machine Learning Applications

description: Dataset consists of triple-wavelength photoplethysmography (PPG) signal, Hb value, age, and gender. The triple-wavelength of PPG signal was measured by a MAXM86161 module sensor that emitted three types of light (green, red and infrared light) and measured using a photodetector. The Hb value was measured by a Hb meter, Nesco Multicheck 2®. Total of 52 subjects (60% female and 40% male) data were collected. The data were collected at Depok City, West Java, Indonesia. This resource is valuable for researchers advancing non-invasive Hb measurement based on machine learning.
DOI: 10.17632/8xbbck45tt.2
title: Triple-Wavelength Photoplethysmography for Hemoglobin Machine Learning Applications

description: Dataset consists of triple-wavelength photoplethysmography (PPG) signal, Hb value, age, and gender. The triple-wavelength of PPG signal was measured by a MAXM86161 module sensor that emitted three types of light (green, red and infrared light) and measured using a photodetector. The Hb value was measured by a Hb meter, Nesco Multicheck 2®. Total of 52 subjects (60% female and 40% male) data were collected. The data were collected at Depok City, West Java, Indonesia. This resource is valuable for researchers advancing non-invasive Hb measurement based on machine learning.
DOI: 10.17632/f6hr5v95nb
title: Variation in Depression Risk by Race and Ethnicity in Vitiligo

description: Supplementary Material
DOI: 10.17632/f6hr5v95nb.2
title: Variation in Depression Risk by Race and Ethnicity in Vitiligo

description: Supplementary Material
DOI: 10.17632/8xh8sx232r
title: A combined enteric neuron-gastric tumor organoid reveals metabolic vulnerabilities in gastric cancer

description: Data S1. Focused library CRISPR screen quality and the aberrant splicing events detected upon knockout of the synthetic lethal gene hit MAGOHB in ARHGAP fusion-containing organoids, related to Figure 2.
A, More than 98% of the sgRNAs were detected within a 5-fold range from the mean reads of sgRNAs as highlighted by the shaded areas.
B, Screen data reproducibility between two biological replicates in the focused library screening.
C, Growth competition assay of organoid lines with (GX052-TO and GX121-TO) and without (GX049-TO, GX068-TO, GX069-TO and GX076-TO) ARHGAP fusion gene with MAGOHB knockout. n = 3.
D, GFP disruption percentage of organoids with MAGOHB knockout in terms of doubling frequency (Number of hours post-sgRNA transduction/Doubling time) normalized to safe harbor.
E, RNA-seq and splicing analyses revealed increased alternative splicing events, along with aberrant changes in spliced intron count at the fusion gene upon MAGOHB knockout, indicate its regulatory role in the splicing of CTNND1-ARHGAP26. Number of total differential alternative splicing events including alternative 3’ splice sites (A3SS), alternative 5’ splice sites (A5SS), mutually exclusive exons (MXE), retained introns (RI) and exon skipping (SE) in GX058-TO upon MAGOHB knockout (left panel). Number of differential alternative splicing events identified in CTNND1 and ARHGAP26 sequences in GX058-TO with MAGOHB knockout (right panel).
F, Fold change of spliced intron counts per million between GX058-TO control and its respective CTNND1-ARHGAP26 knockout clone (upper panel) or with MAGOHB knockout (lower panel) at the indicated genomic coordinates. The fusion gene is identified at chr11: 57810223:+chr5: 143014080 by STAR-Fusion. n = 2.
G, Relative fusion fragments per million total RNA-seq fragments (FFPM) of fusion gene knockout and MAGOHB knockout to controls analyzed by STAR-Fusion. n = 2.
H, Knockout of MAGOHB introduced reduction in CTNND1-ARHGAP26 fusion protein expression. The modest decrease in the fusion exon transcript revealed by STAR-Fusion when MAGOHB was knocked out is evident in the reduction of the fusion protein. 
I, Enriched pathways for genes with at least 5 total differential alterative splicing events in GX058-TO with MAGOHB knockout using Hallmark gene sets. n = 2.
J, Enriched pathways of the downregulated genes in MAGOHB knockout organoids compared with control with reference to Hallmark gene sets. n = 2. The growth inhibition brought by MAGOHB knockout could be due to the reduction of the disease fusion protein level and/or the concomitant alternations of gene expressions in additional pathways.