cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.6536109
title: Northern hemispheric atmospheric ethane trends in the upper troposphere and lower stratosphere (2006-2016) with reference to methane and propane

description: Datasets for northern hemispheric atmospheric ethane, propane and methane (2006-2016) from airborne measurements by IAGOS-CARIBIC project.
DOI: 10.5281/zenodo.7337588
title: Data of horizontal and vertical components of gusty disturbance

description: Observed data of horizontal and vertical gust disturbance components, 70 cases outside the equator and 16 cases near the equator.
DOI: 10.5281/zenodo.8254345
title: A Hybrid Deep Learning-Based Forecasting Model for the Peak Height of Ionospheric F2 Layer

description: The data for paper.
DOI: 10.6073/pasta/85a8f46dabe413973195c8530911088a
title: Santa Barbara Channel Marine BON: Nearshore kelp forest integrated quad and swath cover, 1980-ongoing

description: The Santa Barbara Channel Marine Biodiversity Observation Network (SBCMBON) tracks long-term patterns in species abundance and diversity. This dataset contains counts of algae and invertebrates (both sessile and mobile) by integrating data from four contributing projects working in the kelp forests of the Santa Barbara Channel, USA. The four contributing projects are two research projects: The Santa Barbara Coastal LTER (SBC LTER) and the Partnership for Interdisciplinary Studies of Coastal Oceans (PISCO), the kelp forest monitoring program of the Santa Barbara Channel National Park, and the San Nicolas Island monitoring program supported by USGS. Together, these projects have recorded data for more than 200 species at approximately 100 sites on both the mainland coast and on the Santa Barbara Channel Islands. Sampling began in 1982 and is ongoing. Data were collected by human observation (divers using SCUBA) during regular surveys. The data table documents the number of organisms and the area over which that number was counted for calculation of areal abundance. Data were collected by human observation (divers using SCUBA) during regular surveys. The algae and invertebrate counts record the number of taxa found in each plot, including quad (small square plots such as 1 or 2 m2) and swath (large linear plots such as 60 m2). See Method and protocol for information on integration and data processing. MBON is funded by National Aeronautics and Space Administration (NASA), Bureau of Ocean Energy Management (BOEM), and National Oceanic and Atmospheric Administration (NOAA). For users who are interested in using all or part of this integrated datasets, please contact data owners to discuss your research interests, data-related issues or any other questions. A recommended citation for the data package is available from the download page. In addition, any manuscript generated using this dataset is expected to be sent to the data owners before publication so we can be sure the data is used in the proper context and methods are reported accurately: Santa Barbara Coastal LTER (LTER): Dan Reed dan.reed@lifesci.ucsb.edu Robert Miller miller@msi.ucsb.edu Partnership for Interdisciplinary Studies of Coastal Oceans (PISCO): Jenn Caselle caselle@ucsb.edu Kelp forest monitoring (KFM): David Kushner david_kushner@nps.gov Joshua Sprague joshua_sprague@nps.gov San Nicolas Island monitoring (SNI): Kevin Lafferty Klafferty@usgs.gov Mike Kenner mkenner@ucsc.edu
DOI: 10.6084/m9.figshare.22665025
title: Supplementary Material for: CircARF3 mitigates allergic rhinitis through targeting microRNA-205-5p/sirtuin 5 axis

description: Background: Circular RNAs (circRNAs) are essential in the progression of allergic rhinitis (AR). The purpose of this research is to examine the role of circRNA ADP-ribosylation factor 3 (circARF3) in the pathogenesis of AR. Methods: To generate an animal model of AR, mice were treated with house dust mite (HDM), and mice nasal epithelial cells (NEpCs) were treated with IL-4/IL-13 to imitate the inflammatory damage of AR in vitro. Sanger sequencing, qRT-PCR, and RNAse R digestion assays all validated the circularization structure of circARF3. The levels of CircARF3, miR-205-5p, and sirtuin 5 (SIRT5) were determined by qRT-PCR or western blotting. Luciferase reporter, RNA immunoprecipitation, and pull-down experiments were used to investigate the regulatory network. Flow cytometry was used to investigate the rate of cell apoptosis, and western blotting was used to determine the levels of apoptotic-related proteins (cleaved caspase 3, cleaved Polyadenosine-diphosphate-ribose polymerase) and HMGB1, TLR4, and MyD88. Enzyme-linked immunosorbent assay was used to assess the inflammatory response. Hematoxylin-eosin staining and TUNEL were used to detect the histology of injury and apoptosis of nasal mucosa tissues. Results: CircARF3 and SIRT5 levels were reduced in HDM-treated animals and IL-4/IL-13-treated NEpCs, while miR-205-5p expression was increased. CircARF3 was generated by back-splicing exons 3–5 with a stable circular shape. CircARF3 overexpression mitigated IL-4/IL-13-induced apoptosis in NEpCs by inhibiting miR-205-5p. SIRT5 upregulation attenuated IL-4/IL-13-induced inflammatory injury in NEpCs, and SIRT5 knockdown induced opposite effects. miR-205-5p silencing reversed the effects of SIRT5 knockdown on IL-4/IL-13-induced inflammatory injury. Furthermore, circARF3 overexpression alleviated histological abnormalities, apoptosis, inflammatory response, and HMGB1/TLR4 signaling activation in HDM-treated animals. Conclusion: CircARF3 inhibited cell apoptosis and inflammation via the miR-205-5p/SIRT5 axis in IL-4/IL-13-treated NEpCs and HDM-treated mice.
DOI: 10.6084/m9.figshare.24223444.v1
title: Characteristics of Lunar surface electrons inferred from ARTEMIS observations I: backscattered electrons (Dataset)

description: This dataset contains accompanying data for the manuscript "Characteristics of Lunar surface electrons inferred from ARTEMIS observations I: backscattered electrons" by S. Xu et al.
DOI: 10.17188/1193794
title: Materials Data on MnO by Materials Project

description: MnO is Halite, Rock Salt structured and crystallizes in the trigonal R-3m space group. The structure is three-dimensional. Mn2+ is bonded to six equivalent O2- atoms to form a mixture of edge and corner-sharing MnO6 octahedra. The corner-sharing octahedral tilt angles are 0°. All Mn–O bond lengths are 2.25 Å. O2- is bonded to six equivalent Mn2+ atoms to form a mixture of edge and corner-sharing OMn6 octahedra. The corner-sharing octahedral tilt angles are 0°.
DOI: 10.17632/xdhxyk6yvh.2
title: Data for: Silurian-Devonian lithospheric thinning and thermally softening along the northern margin of the Tarim Craton: geological mapping, petro-structural analysis and geochronological constraints

description: The datasets contain three supplemental tables (Table S1 to S3). Table S1 show the LA-ICP-MS zircon and monazite U-Pb data for the key samples of Korla area, NE Tarim Craton. Table S2 display the Biotite 40Ar/39Ar stepwise heating data of mylonitic granite from the Korla area, NE Tarim Craton. Table S3 show ages data of the Paleozoic igneous rocks from the NE Tarim, eastern STS and CTS domains.
DOI: 10.4121/20787274
title: Data underlying the publication: A cryogenic, coincident fluorescence, electron and ion beam microscope

description: Introduction Data underlying the publication: A cryogenic, coincident fluorescence, electron and ion beam microscope. Publication DOI: 10.7554/eLife.82891 Authors: D.B. Boltje, J.P. Hoogenboom, A.J. Jakobi, G.J. Jensen, C.T.H. Jonker, M.J. Kaag, A.J. Koster, M.G.F. Last, C. de Agrela Pinto, J.M. Plitzko, S. Raunser, S. Tacke, Z. Wang, E.B. van der Wee, R. Wepf, S. den Hoedt Repository created by Daan Boltje General description All data underlying the manuscript figures is stored in this repository. Experiments have been carried out at the Department of Imaging Physics at Delft University of Technology (Delft, NL) in 2020 and 2021 and resulting data are presented in figures 1, 2, 3, 4, 7 and 8. <br> External validation experiments have been carried out at the Department of Structural Biochemistry, Max Planck Institute of Molecular Physiology, (Dortmund, DE) between March-May 2021. The data from these experiments are used in figure 5, 6 and video 1.
DOI: 10.5281/zenodo.7850759
title: WIPP_BATS1_Temperature_Fiber

description: This dataset includes the temperature fiber-optic monitoring data, ERT resistivity data, and thermal couple data from the ERT borehole from BATS 1 conducted at WIPP. The measurements cover the heating cycle from 01/21/2020 to 02/15/2020. WIPP Heater__2019-12-17_23-00-16 (1)_ch1_full.tsv and WIPP Heater__2019-12-17_23-00-16 (1)_ch3_full.tsv are from the 5-m long fiber-optic borehole and the 10-m long fiber-optic borehole, respectively. Array_Heated_Temperature_SN7066_Data_v2.xlsx is the thermal couple data in the ERT borehole. P1_1.csv, P1_2.csv, and P1_3.csv are the resistivity data from three different depths: top (1.7 m from the drift wall), mid (2.9 m from the drift wall), and bottom (4.1 m from the drift wall).
DOI: 10.5281/zenodo.7905013
title: Single particle tracking data for Sittewelle & Royle (2023)

description: A project to analyse intracellular vesicle mobility. A preprint of the manuscript is available at https://doi.org/10.1101/2023.05.10.540182 Code associated with the manuscript can be found at https://github.com/quantixed/p063p036 TrackMate XML files for: ATG9A, Clathrin, EB3, LAMP1, ML1N, Rab5, Rab11, Rab30, Rab35, SCAMP1, SCAMP3, TPD54 TPD54 (pre and post bleach) are available here together with some of the larger outputs from the code. These TrackMate XML files can be processed using TrackMateR as described here or using the code associated with the manuscript. The folders contain calibration csv files which will correct the scaling where required during processing with TrackMateR.
DOI: 10.6084/m9.figshare.21601203
title: Supplementary Material for: Trends of Blood Transfusion According to Diseases in Korea: A 10-Year Nationwide Cohort Study

description: <b><i>Introduction:</i></b> Recent guidelines recommend restrictive red blood cell transfusion; therefore, hospitals have started introducing and implementing patient blood management programs. This is the first study to analyze changes in the trends of blood transfusions in the whole population over the past 10 years according to sex, age group, blood component, disease, and hospital type. <b><i>Methods:</i></b> This cohort study analyzed blood transfusion records for 10 years, from January 2009 to December 2018, using nationwide population-based data from the Korean National Health Insurance Service-Health Screening Cohort database. <b><i>Results:</i></b> The proportion of transfusion procedures conducted in the total population has increased constantly for 10 years. Although its proportion in the age group of 10–79 years decreased, the total number of transfusions increased significantly due to the increase in the population and proportion of transfusions in those aged 80 years or older. Furthermore, the proportion of multicomponent transfusion procedures increased in this age group, which was greater than that of transfusions. The most common disease among transfusion patients in 2009 was cancer, of which gastrointestinal (GI) cancer accounted for more than half, followed by trauma and hematologic diseases (GI cancers &gt; trauma &gt; other cancers &gt; hematologic diseases). The proportion of patients with GI cancer decreased, whereas that of trauma and hematologic diseases increased over the 10 years, with trauma becoming the most common disease type in 2018 (trauma &gt; GI cancers &gt; hematologic diseases &gt; other cancers). Although transfusion rates per hospitalization decreased, the total number of inpatients increased, thus increasing the number of blood transfusions in all types of hospitals. <b><i>Discussion/Conclusions:</i></b> The proportion of transfusion procedures in the total population increased owing to the increase in the total number of transfusions in patients aged 80 years or older. The proportion of patients with trauma and hematologic diseases has also increased. Moreover, the total number of inpatients has been increasing, which subsequently increases the number of blood transfusions performed. Specific management strategies targeting these groups may improve blood management.
DOI: 10.6084/m9.figshare.21881520
title: Supplementary Material for: Structural Correlates of Lifetime Voice-Hearing in Patients with Borderline Personality Disorder: A Pilot Study

description: <b><i>Introduction:</i></b> Auditory verbal hallucinations (AVH) are transdiagnostic phenomena that can occur in several mental disorders, including borderline personality disorder (BPD). Despite the transdiagnostic relevance of these symptoms, very little is known about neural signatures of AVH in BPD. <b><i>Methods:</i></b> We used structural magnetic resonance imaging to investigate multiple markers of brain morphology in BPD patients presenting with a lifetime history of AVH (AVH, <i>n</i> = 6) versus BPD patients without AVH (nAVH, <i>n</i> = 10) and healthy controls (HC, <i>n</i> = 12). The Computational Anatomy Toolbox (CAT12) was used for surface-based morphometric analyses that considered cortical thickness (CTh), gyrification (CG), and complexity of cortical folding (CCF). Factorial models were used to explore differences between AVH patients and HC, as well as between the patient groups. <b><i>Results:</i></b> Compared to HC, AVH patients showed distinct abnormalities in key regions of the language network, i.e., aberrant CTh and CG in right superior temporal gyrus and abnormal CCF in left inferior frontal gyrus. Further abnormalities were found in right prefrontal cortex (CTh) and left orbitofrontal cortex (CCF). Compared to nAVH patients, individuals with AVH showed abnormal CTh in right prefrontal cortex, along with CCF differences in right transverse temporal, superior parietal, and parahippocampal gyri. CG differences between the patient groups were found in left orbitofrontal cortex. <b><i>Conclusion:</i></b> The data suggest a transdiagnostic neural signature of voice-hearing that converges on key regions involved in speech generation and perception, memory and executive control. It is possible that cortical features of distinct evolutionary and genetic origin, i.e., CTh and CG/CCF, differently contribute to AVH vulnerability in BPD.
DOI: 10.6084/m9.figshare.22109693
title: Supplementary Material for: Changes in Inflammatory Markers in Clinical High Risk of Developing Psychosis

description: <b><i>Introduction:</i></b> Immune alterations are associated with the progression of psychosis. However, there are few studies designed to longitudinally measure inflammatory biomarkers during psychotic episodes. We aimed to assess changes in biomarkers from the prodromal phase to psychotic episodes in individuals with clinical high risk (CHR) of psychosis and compare converters and non-converters to psychosis as well as healthy controls (HCs). <b><i>Methods:</i></b> We enrolled 394 individuals with CHR and 100 HCs. A total of 263 individuals with CHR completed the 1-year follow-up, and 47 had converted to psychosis. Interleukin (IL)-1β, 2, 6, 8, 10, tumor necrosis factor-α (TNF-α), and vascular endothelial growth factor levels were measured at baseline and 1 year after completion of the clinical assessment. <b><i>Results:</i></b> The baseline serum levels of IL-10, IL-2, and IL-6 were significantly lower in the conversion group than in the non-conversion group (IL-10, <i>p</i> = 0.010; IL-2, <i>p</i> = 0.023; IL-6, <i>p</i> = 0.012) and HC (IL-6: <i>p</i> = 0.034). Self-controlled comparisons showed that IL-2 changed significantly (<i>p</i> = 0.028), and IL-6 levels tended toward significance (<i>p</i> = 0.088) in the conversion group. In the non-conversion group, serum levels of TNF-α (<i>p</i> = 0.017) and VEGF (<i>p</i> = 0.037) changed significantly. Repeated measures analysis of variance revealed a significant time effect related to TNF-α (<i>F</i> = 4.502, <i>p</i> = 0.037, effect size (η<sup>2</sup>) = 0.051), a group effect related to IL-1β (<i>F</i> = 4.590, <i>p</i> = 0.036, η<sup>2</sup> = 0.062), and IL-2 (<i>F</i> = 7.521, <i>p</i> = 0.011, η<sup>2</sup> = 0.212), but no time × group effect. <b><i>Discussion:</i></b> Alterations in the serum levels of inflammatory cytokines were found to precede the first episode of psychosis in the CHR population, particularly for those who later converted to psychosis. Longitudinal analysis supports the varied roles of cytokines in individuals with CHR with later psychotic conversion or non-conversion outcomes.
DOI: 10.6084/m9.figshare.22116863
title: Supplementary Material for: Serum potassium trajectory during AKI and mortality risk

description: Background: The association between potassium (sK) level trajectory and mortality or the need for kidney replacement therapy (KRT) during acute kidney injury (AKI) has not been adequately explored. Methods: In this prospective cohort, AKI patients admitted to the Hospital Civil de Guadalajara were enrolled. Eight groups based on the sK (mEq/L) level trajectories during 10 days of hospitalization were created, (1) normokalemia (normoK), defined as sK between 3.5-5.5; (2) hyperkalemia to normoK; (3) hypokalemia to normoK; (4) fluctuating potassium; (5) persistent hypoK; (6) normoK to hypoK; (7) normoK to hyperK; (8) persistent hyperK. We assessed the association of sK trajectories with mortality and the need for KRT. Results: A total of 311 AKI patients were included. The mean age 52.6 years, and 58.6% were male. AKI stage 3 was present in 63.9%. KRT started in 36% patients, and 21.2% died. After adjusting for confounders, 10-day hospital mortality was significantly higher in group 7 and 8 (OR, 1.35 and 1.61, p = &lt;0.05, for both, respectively), and KRT initiation was higher only in group 8 (OR 1.38, p = &lt; 0.05) compared with group 1. Mortality in different subgroups of patients in group 8 did not change the primary results. Conclusion: In our prospective cohort, most patients with AKI had alterations in sK+. NormoK to hyperK and persistent hyperK were associated with death, while only persistent hyperK was correlated with the need for KRT.
DOI: 10.6084/m9.figshare.22241053
title: Supplementary Material for: Predicting Individual Patient Platelet Demand in a Large Tertiary Care Hospital Using Machine Learning

description: <b><i>Introduction:</i></b> An increasing shortage of donor blood is expected, considering the demographic change in Germany. Due to the short shelf life and varying daily fluctuations in consumption, the storage of platelet concentrates (PCs) becomes challenging. This emphasizes the need for reliable prediction of needed PCs for the blood bank inventories. Therefore, the objective of this study was to evaluate multimodal data from multiple source systems within a hospital to predict the number of platelet transfusions in 3 days on a per-patient level. <b><i>Methods:</i></b> Data were collected from 25,190 (42% female and 58% male) patients between 2017 and 2021. For each patient, the number of received PCs, platelet count blood tests, drugs causing thrombocytopenia, acute platelet diseases, procedures, age, gender, and the period of a patient’s hospital stay were collected. Two models were trained on samples using a sliding window of 7 days as input and a day 3 target. The model predicts whether a patient will be transfused 3 days in the future. The model was trained with an excessive hyperparameter search using patient-level repeated 5-fold cross-validation to optimize the average macro F2-score. <b><i>Results:</i></b> The trained models were tested on 5,022 unique patients. The best-performing model has a specificity of 0.99, a sensitivity of 0.37, an area under the precision-recall curve score of 0.45, an MCC score of 0.43, and an F1-score of 0.43. However, the model does not generalize well for cases when the need for a platelet transfusion is recognized. <b><i>Conclusion:</i></b> A patient AI-based platelet forecast could improve logistics management and reduce blood product waste. In this study, we build the first model to predict patient individual platelet demand. To the best of our knowledge, we are the first to introduce this approach. Our model predicts the need for platelet units for 3 days in the future. While sensitivity underperforms, specificity performs reliably. The model may be of clinical use as a pretest for potential patients needing a platelet transfusion within the next 3 days. As sensitivity needs to be improved, further studies should introduce deep learning and wider patient characterization to the methodological multimodal, multisource data approach. Furthermore, a hospital-wide consumption of PCs could be derived from individual predictions.
DOI: 10.6084/m9.figshare.22353037
title: Supplementary Material for: Effect of Fentanyl for Preterm Infants on Mechanical Ventilation: A Systematic Review and Meta-Analysis

description: <b><i>Introduction:</i></b> Because excessive physical stress is harmful, reducing pain and discomfort in premature neonates during mechanical ventilation is a major challenge for physicians. There are no consensus and systematic review on the use of fentanyl, the most commonly used pain reliever in preterm neonates during mechanical ventilation. We aim to compare the benefits and harms of fentanyl versus placebo or no drug for preterm neonates receiving mechanical ventilation. <b><i>Methods:</i></b> A systematic review of randomized controlled trials (RCTs) was conducted according to the Cochrane Handbook for Systematic Reviews of Interventions. The systematic review was reported using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement. Scientific databases such as MEDLINE, Embase, CENTRAL, and CINAHL were searched. All preterm infants on mechanical ventilation and enrolled in an RCT of fentanyl versus control were included. <b><i>Results:</i></b> Of 256 reports initially retrieved, 4 reports met the eligibility criteria. Fentanyl was not associated with mortality risk compared to the control (risk ratio: 0.72, 95% confidence intervals [CIs]: 0.36–1.44). No increase in ventilation duration (mean difference [MD]: 0.04, 95% CIs: −0.63–0.71) and no effect on hospital stay length (MD: 4.00, 95% CIs: −7.12–15.12) were found. Fentanyl intervention does not affect any other morbidities, including bronchopulmonary dysplasia, periventricular leukomalacia, patent ductus arteriosus, intraventricular hemorrhage (IVH), severe IVH, sepsis, and necrotizing enterocolitis. <b><i>Conclusion:</i></b> The present systematic review and meta-analysis failed to demonstrate the benefit of administering fentanyl to preterm infants on mechanical ventilation in mortality and morbidities. Follow-up studies are required to investigate the long-term neurodevelopment of the children.