cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.23632482
title: Julia code for generating figures 1, 2 and supplementary figure 2 from Astrocyte endfeet may theoretically act as valves to convert pressure oscillations to glymphatic flow

description: The glymphatic system of cerebrospinal fluid transport through the perivascular spaces of the brain has been implicated in metabolic waste clearance, neurodegenerative diseases and in acute neurological disorders such as stroke and cardiac arrest. In other biological low-pressure fluid pathways such as in veins and the peripheral lymphatic system, valves play an important role in ensuring the flow direction. Though fluid pressure is low in the glymphatic system and directed bulk flow has been measured in pial and penetrating perivascular spaces, no valves have yet been identified. Valves, which asymmetrically favour forward flow to backward flow, would imply that the considerable oscillations in blood and ventricle volumes seen in magnetic resonance imaging could cause directed bulk flow. Here, we propose that astrocyte endfeet may act as such valves using a simple elastic mechanism. We combine a recent fluid mechanical model of viscous flow between elastic plates with recent measurements of <i>in vivo</i> elasticity of the brain to predict order of magnitude flow-characteristics of the valve. The modelled endfeet are effective at allowing forward while preventing backward flow.
DOI: 10.6084/m9.figshare.23632482.v1
title: Julia code for generating figures 1, 2 and supplementary figure 2 from Astrocyte endfeet may theoretically act as valves to convert pressure oscillations to glymphatic flow

description: The glymphatic system of cerebrospinal fluid transport through the perivascular spaces of the brain has been implicated in metabolic waste clearance, neurodegenerative diseases and in acute neurological disorders such as stroke and cardiac arrest. In other biological low-pressure fluid pathways such as in veins and the peripheral lymphatic system, valves play an important role in ensuring the flow direction. Though fluid pressure is low in the glymphatic system and directed bulk flow has been measured in pial and penetrating perivascular spaces, no valves have yet been identified. Valves, which asymmetrically favour forward flow to backward flow, would imply that the considerable oscillations in blood and ventricle volumes seen in magnetic resonance imaging could cause directed bulk flow. Here, we propose that astrocyte endfeet may act as such valves using a simple elastic mechanism. We combine a recent fluid mechanical model of viscous flow between elastic plates with recent measurements of <i>in vivo</i> elasticity of the brain to predict order of magnitude flow-characteristics of the valve. The modelled endfeet are effective at allowing forward while preventing backward flow.
DOI: 10.5281/zenodo.7787589
title: Gene-based association analysis for back pain-related phenotypes, results

description: Results of gene-based association analysis of back pain-related phenotypes using imputed genotypes (500K GWAS) and exome sequencing data (200K WES) from the UK Biobank. Back pain-related phenotypes: CBP - chronic back pain IDD - Intervertebral disc disorder defined by the ICD-10 code M51 Dorsalgia, defined by the ICD-10 code M54 SGIT - linear combination of the above original traits, obtained as described by Svishcheva et al. (doi: 10.3390/genes13101694)
DOI: 10.5281/zenodo.7787590
title: Gene-based association analysis for back pain-related phenotypes, results

description: Results of exome-wide gene-based association analysis of back pain-related phenotypes using exome sequencing data from a UK biobank project, 200k release. Back pain-related phenotypes: CBP - chronic back pain IDD - Intervertebral disc disorder defined by the ICD-10 code M51 Dorsalgia, defined by the ICD-10 code M54 SGIT - linear combination of the above original traits, obtained as described by Svishcheva et al. (doi: 10.3390/genes13101694)
DOI: 10.5281/zenodo.8118630
title: Gene-based association analysis for back pain-related phenotypes, results

description: Results of gene-based association analysis of back pain-related phenotypes using imputed genotypes (500K GWAS) and exome sequencing data (200K WES) from the UK Biobank. Back pain-related phenotypes: CBP - chronic back pain IDD - Intervertebral disc disorder defined by the ICD-10 code M51 Dorsalgia, defined by the ICD-10 code M54 SGIT - linear combination of the above original traits, obtained as described by Svishcheva et al. (doi: 10.3390/genes13101694)
DOI: 10.6084/m9.figshare.23632530
title: Additional file 1 of How does the work-life balance impact stress on primary healthcare workers during the COVID-19 pandemic?

description: Additional file 1: Supplementary Table 1. Correlations among variables.
DOI: 10.6084/m9.figshare.23632530.v1
title: Additional file 1 of How does the work-life balance impact stress on primary healthcare workers during the COVID-19 pandemic?

description: Additional file 1: Supplementary Table 1. Correlations among variables.
DOI: 10.6084/m9.figshare.23632542
title: Additional file 1 of Segregation between breeds and local breed proportions in genetic and genomic models for crossbreds

description: Additional file 1. It contains the QMSim instruction file for the simulation in Example II.
DOI: 10.6084/m9.figshare.23632542.v1
title: Additional file 1 of Segregation between breeds and local breed proportions in genetic and genomic models for crossbreds

description: Additional file 1. It contains the QMSim instruction file for the simulation in Example II.
DOI: 10.6084/m9.figshare.23632545
title: Additional file 2 of Segregation between breeds and local breed proportions in genetic and genomic models for crossbreds

description: Additional file 2. It contains the Julia code for the construction and inversion of the relationship matrices used in Example II.
DOI: 10.6084/m9.figshare.23632545.v1
title: Additional file 2 of Segregation between breeds and local breed proportions in genetic and genomic models for crossbreds

description: Additional file 2. It contains the Julia code for the construction and inversion of the relationship matrices used in Example II.
DOI: 10.6084/m9.figshare.23632690.v1
title: Additional file 1 of Prevalence and risk factors determinants of the non-use of insecticide-treated nets in an endemic area for malaria: analysis of data from Cameroon

description: Additional file 1. The database generated and used in the current study showing demographic characteristics information (including sex, age, date of birth, educational level) of household members, ownership and usage of nets, preferences and continuous use of the mosquito nets.
DOI: 10.6084/m9.figshare.23632690
title: Additional file 1 of Prevalence and risk factors determinants of the non-use of insecticide-treated nets in an endemic area for malaria: analysis of data from Cameroon

description: Additional file 1. The database generated and used in the current study showing demographic characteristics information (including sex, age, date of birth, educational level) of household members, ownership and usage of nets, preferences and continuous use of the mosquito nets.
DOI: 10.6084/m9.figshare.23632707
title: Additional file 2 of Effect of ready-to-use therapeutic foods on time to recovery among children with severe acute malnutrition in Ethiopia: a prospective cohort study

description: Supplementary Material 2
DOI: 10.6084/m9.figshare.23632707.v1
title: Additional file 2 of Effect of ready-to-use therapeutic foods on time to recovery among children with severe acute malnutrition in Ethiopia: a prospective cohort study

description: Supplementary Material 2
DOI: 10.6084/m9.figshare.23632720
title: Additional file 2 of Staff perspectives on the influence of patient characteristics on alarm management in the intensive care unit: a cross-sectional survey study

description: Supplementary Material 2
DOI: 10.6084/m9.figshare.23632720.v1
title: Additional file 2 of Staff perspectives on the influence of patient characteristics on alarm management in the intensive care unit: a cross-sectional survey study

description: Supplementary Material 2
DOI: 10.6084/m9.figshare.23632723
title: Additional file 3 of Staff perspectives on the influence of patient characteristics on alarm management in the intensive care unit: a cross-sectional survey study

description: Supplementary Material 3
DOI: 10.6084/m9.figshare.23632723.v1
title: Additional file 3 of Staff perspectives on the influence of patient characteristics on alarm management in the intensive care unit: a cross-sectional survey study

description: Supplementary Material 3
DOI: 10.5281/zenodo.7909733
title: Confocal data of Dictyorachys callidictyus, holotype, NIGP201153

description: This dataset contains the raw confocal laser scanning microscopy (CLSM) slices for the holotype of <em>Dictyorachys callidictyus</em> (NIGP201153) from mid-Cretaceous Burmese amber. This dataset is associated with the publication "<em>Dictyorachys</em> gen. nov., an enigmatic genus of jewel beetles from mid-Cretaceous amber of northern Myanmar (Coleoptera: Buprestidae)" (DOI:10.3140/bull.geosci.1875). Confocal images were obtained with a Zeiss LSM710 confocal laser scanning microscope, using the 561 nm (DPSS 561-10) laser excitation line. The original CZI files are provided, which could be opened by the ZEISS ZEN software.
DOI: 10.5281/zenodo.7909734
title: Confocal data of Dictyorachys callidictyus, holotype, NIGP201153

description: This dataset contains the raw confocal laser scanning microscopy (CLSM) slices for the holotype of <em>Dictyorachys callidictyus</em> (NIGP201153) from mid-Cretaceous Burmese amber. This dataset is associated with the publication "<em>Dictyorachys</em> gen. nov., an enigmatic genus of jewel beetles from mid-Cretaceous amber of northern Myanmar (Coleoptera: Buprestidae)" (DOI:10.3140/bull.geosci.1875). Confocal images were obtained with a Zeiss LSM710 confocal laser scanning microscope, using the 561 nm (DPSS 561-10) laser excitation line. The original CZI files are provided, which could be opened by the ZEISS ZEN software.
DOI: 10.5519/qd.cq6u50pl
title: Query on the Natural History Museum Data Portal (data.nhm.ac.uk) (1 records)
DOI: 10.6084/m9.figshare.21652112
title: A reinvestigation of multiple independent evolution and Triassic-Jurassic origin of multicellular Volvocine algae

description: The evolution of multicellular organisms is considered to be a major evolutionary transition, profoundly affecting the ecology and evolution of nearly all life on earth. The volvocine algae, a unique clade of chlorophytes with diverse cell morphology, provide an appealing model for investigating the evolution of multicellularity and development. However, the phylogenetic relationship and timescale of the volvocine algae are not fully resolved. Here, we use extensive taxon and gene sampling to reconstruct the phylogeny of the volvocine algae. Our results support that the colonial volvocine algae are not monophyletic group, and multicellularity independently evolve at least twice in the volvocine algae, once in Tetrabaenaceae and another in the Goniaceae + Volvocaceae. The simulation analyses suggest that incomplete lineage sorting is a major factor for the tree topology discrepancy, which imply that the multispecies coalescent model better fit the data used in this study. The coalescent-based species tree supported that the Goniaceae is monophyletic, Crucicarteria is the earliest diverging lineage, followed by Hafniomonas and Radicarteria within the Volvocales, and the four incertae sedis taxa and Sphaeropleales grouped into a monophyletic lineage. By considering the multiple uncertainties in divergence time estimation, the dating analyses indicate that the volvocine algae occurred during the Cryogenian to Ediacaran (696.6–551.1 Ma), and multicellularity in the volvocine algae originated from the Triassic to Jurassic. Our phylogeny and timeline provide an evolutionary framework for studying the evolution of key traits and the origin of multicellularity in the volvocine algae.
DOI: 10.6084/m9.figshare.21652112.v1
title: A reinvestigation of multiple independent evolution and Triassic-Jurassic origin of multicellular Volvocine algae

description: The evolution of multicellular organisms is considered to be a major evolutionary transition, profoundly affecting the ecology and evolution of nearly all life on earth. The volvocine algae, a unique clade of chlorophytes with diverse cell morphology, provide an appealing model for investigating the evolution of multicellularity and development. However, the phylogenetic relationship and timescale of the volvocine algae are not fully resolved. Here, we use extensive taxon and gene sampling to reconstruct the phylogeny of the volvocine algae. Our results support that the colonial volvocine algae are not monophyletic group, and multicellularity independently evolve at least twice in the volvocine algae, once in Tetrabaenaceae and another in the Goniaceae + Volvocaceae. The simulation analyses suggest that incomplete lineage sorting is a major factor for the tree topology discrepancy, which imply that the multispecies coalescent model better fit the data used in this study. The coalescent-based species tree supported that the Goniaceae is monophyletic, Crucicarteria is the earliest diverging lineage, followed by Hafniomonas and Radicarteria within the Volvocales, and the four incertae sedis taxa and Sphaeropleales grouped into a monophyletic lineage. By considering the multiple uncertainties in divergence time estimation, the dating analyses indicate that the volvocine algae occurred during the Cryogenian to Ediacaran (696.6–551.1 Ma), and multicellularity in the volvocine algae originated from the Triassic to Jurassic. Our phylogeny and timeline provide an evolutionary framework for studying the evolution of key traits and the origin of multicellularity in the volvocine algae.
DOI: 10.5281/zenodo.8118719
title: Natural history specimens collected and/or identified and deposited.

description: Natural history specimen data collected and/or identified by Bartholomew Anthony Maina, http://www.wikidata.org/entity/Q120378903. Claims or attributions were made on Bionomia, https://bionomia.net using specimen data from the Global Biodiversity Information Facility, https://gbif.org.
description: http://www.wikidata.org/entity/Q120378903
DOI: 10.5281/zenodo.8118718
title: Natural history specimens collected and/or identified and deposited.

description: Natural history specimen data collected and/or identified by Bartholomew Anthony Maina, http://www.wikidata.org/entity/Q120378903. Claims or attributions were made on Bionomia, https://bionomia.net using specimen data from the Global Biodiversity Information Facility, https://gbif.org.
description: http://www.wikidata.org/entity/Q120378903
DOI: 10.6084/m9.figshare.23633643
title: DATABASE.xlsx

description: Database from : <strong>Melatonin as Adjunctive Therapy for Neonatal Sepsis: </strong> <strong>Systematic Review and Meta-analysis</strong>
DOI: 10.5281/zenodo.8118744
title: Natural history specimens collected and/or identified and deposited.

description: Natural history specimen data collected and/or identified by Walter Richard Suter, http://www.wikidata.org/entity/Q120379149. Claims or attributions were made on Bionomia, https://bionomia.net using specimen data from the Global Biodiversity Information Facility, https://gbif.org.
description: http://www.wikidata.org/entity/Q120379149
DOI: 10.5281/zenodo.8118743
title: Natural history specimens collected and/or identified and deposited.

description: Natural history specimen data collected and/or identified by Walter Richard Suter, http://www.wikidata.org/entity/Q120379149. Claims or attributions were made on Bionomia, https://bionomia.net using specimen data from the Global Biodiversity Information Facility, https://gbif.org.
description: http://www.wikidata.org/entity/Q120379149
DOI: 10.5281/zenodo.8118472
title: The mutational landscape of a US Midwestern breast cancer cohort reveals subtype-specific cancer drivers and prognostic markers

description: Supplementary Figures and Tables for the manuscript.
DOI: 10.5281/zenodo.8118738
title: The mutational landscape of a US Midwestern breast cancer cohort reveals subtype-specific cancer drivers and prognostic markers

description: Supplementary Figures and Tables for the manuscript.
DOI: 10.21227/aqcq-6552
title: Rotated reconstructed 3D imaging results

description: Supplementary material of the article "Precise 2D and 3D fluoroscopic Imaging by　using an FMCW Millimeter-Wave Radar".A wrench, and a hammer were packed inside a cardboard box as an imaging sample, to ensure stability, foam cushioning material was used to fix the tools within the boxes. We conducted object scanning from four distinct directions at 90-degree intervals. The acquired data was then reconstructed, and the results from each direction were stitched together, considering the respective scanning angles. This supplementary material shows the reconstructed 3D point cloud image, the red point cloud is the wrench, the orange point cloud is the hammer, and the blue point cloud represents the front and back of the box.
DOI: 10.6084/m9.figshare.23172785.v1
title: Supplementary Material for: Burden of acute kidney injury among adult hospital patients in the Italian Lombardy Region – a 20 years real world data analysis

description: Background: Acute kidney injury (AKI) is a frequent condition, with persisted shortage of large-scale epidemiological studies. We analyzed the population-wide healthcare system of the Italian Lombardy region over the 2000-2019 period, and evaluated AKI incidence, mortality, and related healthcare resources utilization and cost in all citizens 40 years and older. Methods: The retrospective cohort analysis of an administrative claims database that routinely collects information about health care provision in a high-income region with 10 million citizens. Over 20 years, AKI was identified in 84,384 hospital discharge records by the International Classification of Diseases 9th Revision codes (mean age 77.4±11.6 years, 52.5% were males). Results: From 2000 to 2019, the AKI rates per 100,000 population changed from 32.9 to 90.5 for incidence, from 4.7 to 11.9 for mortality, and from 32.3 to 44.1 for years of life lost (YLLs), respectively. In-hospital mortality changed slightly (14.2% and 13.2%, respectively), while 30-day mortality decreased from 21.5% to 17.4%, respectively. Incidence rates increased with age and were higher in males, and varied almost four-fold between provinces. The median hospitalization cost was €4,014 (IQR 3,652; 4,134), and the annual cost of treatment risen from €5.2 million in 2000 to €22.9 million in 2019. Hemodialysis was administered in 7.4% of hospitalizations. Over the total study period the cumulative AKI burden accounted for 11,420 in-hospital deaths, 63,370.8 YLLs, and €329 million of direct cost. Conclusions: This real-world analysis demonstrates the high burden of AKI with prominent geographical differences that require further implementation of preventive and diagnostic actions.
DOI: 10.6084/m9.figshare.23172785
title: Supplementary Material for: Burden of acute kidney injury among adult hospital patients in the Italian Lombardy Region – a 20 years real world data analysis

description: Background: Acute kidney injury (AKI) is a frequent condition, with persisted shortage of large-scale epidemiological studies. We analyzed the population-wide healthcare system of the Italian Lombardy region over the 2000-2019 period, and evaluated AKI incidence, mortality, and related healthcare resources utilization and cost in all citizens 40 years and older. Methods: The retrospective cohort analysis of an administrative claims database that routinely collects information about health care provision in a high-income region with 10 million citizens. Over 20 years, AKI was identified in 84,384 hospital discharge records by the International Classification of Diseases 9th Revision codes (mean age 77.4±11.6 years, 52.5% were males). Results: From 2000 to 2019, the AKI rates per 100,000 population changed from 32.9 to 90.5 for incidence, from 4.7 to 11.9 for mortality, and from 32.3 to 44.1 for years of life lost (YLLs), respectively. In-hospital mortality changed slightly (14.2% and 13.2%, respectively), while 30-day mortality decreased from 21.5% to 17.4%, respectively. Incidence rates increased with age and were higher in males, and varied almost four-fold between provinces. The median hospitalization cost was €4,014 (IQR 3,652; 4,134), and the annual cost of treatment risen from €5.2 million in 2000 to €22.9 million in 2019. Hemodialysis was administered in 7.4% of hospitalizations. Over the total study period the cumulative AKI burden accounted for 11,420 in-hospital deaths, 63,370.8 YLLs, and €329 million of direct cost. Conclusions: This real-world analysis demonstrates the high burden of AKI with prominent geographical differences that require further implementation of preventive and diagnostic actions.
DOI: 10.6084/m9.figshare.23633679
title: <em>Spodoptera litura</em> fasta sequence (South Korea)

description: Mutation survey (I4790M) of partial sequence ryanodine receptor (RyR) <em>Spodoptera litura</em> sequence (South Korea)
DOI: 10.6084/m9.figshare.23633679.v1
title: <em>Spodoptera litura</em> fasta sequence (South Korea)

description: Mutation survey (I4790M) of partial sequence ryanodine receptor (RyR) <em>Spodoptera litura</em> sequence (South Korea)
DOI: 10.6084/m9.figshare.23627751
title: Mutation survey_(G4946E)_fasta file

description: Mutation survey (G4946E) of partial sequnce ryanodine receptor (RyR) Spodioptera exigua (BAW) and their sequence file
DOI: 10.6084/m9.figshare.23627751.v1
title: Mutation survey_(G4946E)_fasta file

description: Mutation survey (G4946E) of partial sequnce ryanodine receptor (RyR) Spodioptera exigua (BAW) and their sequence file
DOI: 10.6084/m9.figshare.23627358
title: BAW_Whole Genome annotation and assembly

description: <strong>Supplementary data provides further details on this assembly and</strong> <strong>annotation process. </strong> <em><strong>Genome sequencing and assembly of Spodoptera exigua </strong></em><strong>(BAW)</strong>
DOI: 10.6084/m9.figshare.23627358.v1
title: BAW_Whole Genome annotation and assembly

description: <strong>Supplementary data provides further details on this assembly and</strong> <strong>annotation process. </strong> <em><strong>Genome sequencing and assembly of Spodoptera exigua </strong></em><strong>(BAW)</strong>
DOI: 10.6084/m9.figshare.23617185
title: I4790M_mutation survey_fasta.txt

description: The mutation was checked in the Korean and USA museum specimens and new samples (without bioassay, refer to manuscript Fig. 2 B.)
DOI: 10.6084/m9.figshare.23617185.v1
title: I4790M_mutation survey_fasta.txt

description: The mutation was checked in the Korean and USA museum specimens and new samples (without bioassay, refer to manuscript Fig. 2 B.)
DOI: 10.15151/esrf-es-1117954265
title: Structural Biology of Macromolecules and Macromolecular complexes from India

description: Structural biology research groups located in India constitute the INDIA-BAG and will utilize MX & SAXS to study different biological macromolecules. The non-proprietary agreement signed between ESRF and the Department of Biotechnology (DBT) enables studies that provide fundamental mechanistic insight regarding different biological processes. A brief description of over 50 research groups is provided in the global summary and a summary of their research contributions involving data collected at ESRF is provided in the 2 year BAG report. The ESRF-India partnership is supported by a single grant provided to the RCB by the DBT. Please note that a report listing no. of shifts utilized, details of users and the research output from these visits has to be sent to the DBT to obtain release of funds to pay ESRF membership dues. Consequently, all the structural biologists from India are grouped in a single BAG to enable monitoring of progress to collect the required statistics.