cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7007951.v1
title: Exploring population responses to environmental change when there is never enough data; a factor analytic approach

description: These are the two demographic datasets used in the manuscript "Exploring population responses to environmental change when there is never enough data; a factor analytic approach".<br>Abstract1. Temporal variability in the environment drives variation in vital rates, with consequences for population dynamics and life history evolution. Integral projection models (IPMs) are data-driven structured population models widely used to study population dynamics and life history evolution in temporally variable environments. However, many data sets have insufficient temporal replication for the environmental drivers of vital rates to be identified with confidence, limiting their use for evaluating population level responses to environmental change.2. Parameter selection, where the kernel is constructed at each time step by randomly selecting the time-varying parameters from their joint probability distribution, is one approach to including stochasticity in IPMs. We consider a factor analytic (FA) approach for modelling the covariance matrix of time-varying parameters, whereby latent variable(s) describe the covariance among vital rate parameters. This decreases the number of parameters to estimate and, where the covariance is positive, the latent variable can be interpreted as a measure of environmental quality. We demonstrate this using simulation studies and two case studies.3. The simulation studies suggest the FA approach provides similarly accurate estimates of stochastic population growth rate to estimating an unstructured covariance matrix. We demonstrate how the latent parameter can be perturbed to show how selection on reproductive delays in the monocarp <i>Carduus nutans </i>changes under different environmental conditions. We develop a demographic model of the fire dependent herb <i>Eryngium cuneifolium</i> to show how a putative driver of the variation in environmental quality can be incorporated with the addition of a single parameter. Using perturbation analyses we determine optimal management strategies for this species.4. This approach estimates fewer parameters than previous approaches and allows novel eco-evolutionary insights. Predictions on population dynamics and life history evolution under different environmental conditions can be made without necessarily identifying causal factors. Putative environmental drivers can be incorporated with relatively few parameters, allowing for predictions on how populations will respond to changes in the environment.<br>The <i>Carduus nutans</i> data are owned by CSIRO. The <i>Eryngium cuneifolium </i>were provided by the Archbold Biological Station. Example code for parameterising an IPM using the FA approach are available on github with DOI: http://doi.org/10.5281/zenodo.1312855.
DOI: 10.6084/m9.figshare.7007921
title: Orsini et al., ATVB

description: raw data from Orsini et al., ATVB<br>
DOI: 10.6084/m9.figshare.7007921.v1
title: Orsini et al., ATVB

description: raw data from Orsini et al., ATVB<br>
DOI: 10.6084/m9.figshare.7007858
title: Bystander Assistance for Trauma Victims in Low- and Middle-Income Countries: A Systematic Review of Prevalence and Training Interventions

description: <b>Objective:</b> Lack of organized prehospital care may contribute to the disproportionate burden of trauma-related deaths in low- and middle-income countries (LMICs). The World Health Organization (WHO) recommends bystander training in basic principles of first aid and victim transport; however, prevalence of bystander or layperson assistance to trauma victims in LMICs has not been well-described, and organized reviews of existing evidence for bystander training are lacking. This systematic review aims to 1) describe the prevalence of bystander or layperson aid or transport for trauma victims in the prehospital setting in LMICs and 2) ascertain impacts of bystander training interventions in these settings. <b>Methods:</b> A systematic search of OVID Medline, Cochrane Library, and relevant gray literature was conducted. We included 1) all studies detailing prevalence of bystander-administered aid or transport for trauma victims in LMICs and 2) all randomized controlled trials and observational studies evaluating bystander training interventions. We extracted study characteristics, interventions, and outcomes data. Study quality was assessed using Grading of Recommendations Assessment, Development and Evaluation (GRADE) criteria. <b>Results:</b> Sixty-two studies detailed prevalence of bystander transport and aid. Family members, police, and bus or taxi drivers commonly transported patients; a majority of patients, up to &gt;94%, received aid from bystanders. Twenty-four studies examined impacts of training interventions. Only one study looked at transport interventions; the remainder addressed first aid training. Interventions varied in content, duration, and target learners. Evidence was generally of low quality, but all studies demonstrated improvements in layperson knowledge and skills. Five studies reported a mortality reduction. <b>Conclusions:</b> Heterogeneity in data reporting and outcomes limited formal meta-analysis. However, this review shows high rates of bystander involvement in prehospital trauma care and transport in LMICs and highlights the need for bystander training. Bystander training in these settings is feasible and may have an important impact on meaningful outcomes such as mortality. Categories of involved bystanders varied by region and training interventions should be targeted at relevant groups. “Train the trainer” models appear promising in securing community engagement and maximizing participation. Further research is needed to examine the value of bystander transport networks in trauma.
DOI: 10.6084/m9.figshare.7007903
title: Dataset analysing the crossover between archivists, recordkeeping professionals and research data management using email list data

description: This dataset relates to research on the connections between archives professionals and research data management. It consists of a single Excel spreadsheet with four sheets, containing an analysis of emails sent to two email discussions lists: Archives-NRA (Archivists, conservators and records managers) and Research-Dataman. The coded dataset and a list of codes used for each mailing list is provided.<br>The two datasets were downloaded from the JiscMail Email Discussion list archives on 27 July 2018. <br>The Archives-NRA dataset was compiled by conducting a free text search for "research data" on the mailing list's archives, and the metadata for every search result was downloaded and coded (144 metadata records in total). <br>The resulting coded dataset demonstrates how frequently archivists and records professionals discuss research data on the Archives-NRA list, the topics which are discussed, and an increase in these discussions over time. <br><br>The Research-Dataman dataset was compiled by conducting a free text search for "archivist" on the mailing list's archives, and the metadata for every search result was downloaded and coded (197 emails total). <br>The resulting coded dataset demonstrates how frequently data management professionals seek the advice of archivists or advertise vacancies for archivists, and how often archivists email this mailing list. <br>The names and email addresses of the mailing list participants have been redacted for privacy reasons but the original full-text emails can be accessed by members of the respective mailing lists using the URLs provided in the dataset.<br><br><br>
DOI: 10.6084/m9.figshare.7007858.v1
title: Bystander Assistance for Trauma Victims in Low- and Middle-Income Countries: A Systematic Review of Prevalence and Training Interventions

description: <b>Objective:</b> Lack of organized prehospital care may contribute to the disproportionate burden of trauma-related deaths in low- and middle-income countries (LMICs). The World Health Organization (WHO) recommends bystander training in basic principles of first aid and victim transport; however, prevalence of bystander or layperson assistance to trauma victims in LMICs has not been well-described, and organized reviews of existing evidence for bystander training are lacking. This systematic review aims to 1) describe the prevalence of bystander or layperson aid or transport for trauma victims in the prehospital setting in LMICs and 2) ascertain impacts of bystander training interventions in these settings. <b>Methods:</b> A systematic search of OVID Medline, Cochrane Library, and relevant gray literature was conducted. We included 1) all studies detailing prevalence of bystander-administered aid or transport for trauma victims in LMICs and 2) all randomized controlled trials and observational studies evaluating bystander training interventions. We extracted study characteristics, interventions, and outcomes data. Study quality was assessed using Grading of Recommendations Assessment, Development and Evaluation (GRADE) criteria. <b>Results:</b> Sixty-two studies detailed prevalence of bystander transport and aid. Family members, police, and bus or taxi drivers commonly transported patients; a majority of patients, up to &gt;94%, received aid from bystanders. Twenty-four studies examined impacts of training interventions. Only one study looked at transport interventions; the remainder addressed first aid training. Interventions varied in content, duration, and target learners. Evidence was generally of low quality, but all studies demonstrated improvements in layperson knowledge and skills. Five studies reported a mortality reduction. <b>Conclusions:</b> Heterogeneity in data reporting and outcomes limited formal meta-analysis. However, this review shows high rates of bystander involvement in prehospital trauma care and transport in LMICs and highlights the need for bystander training. Bystander training in these settings is feasible and may have an important impact on meaningful outcomes such as mortality. Categories of involved bystanders varied by region and training interventions should be targeted at relevant groups. “Train the trainer” models appear promising in securing community engagement and maximizing participation. Further research is needed to examine the value of bystander transport networks in trauma.
DOI: 10.6084/m9.figshare.7007774
title: All slices - detail

description: 12 Slices from 4 subjects, scanned in MRI via spiral trajectory , reconstructed with a Minimal Linear Network.<br>
DOI: 10.6084/m9.figshare.7007774.v1
title: All slices - detail

description: 12 Slices from 4 subjects, scanned in MRI via spiral trajectory , reconstructed with a Minimal Linear Network.<br>
DOI: 10.7284/107396
title: GNSS (Global Navigation Satellite System) data collected during research cruise EN507 using a Furuno GP-90D instrument system onboard the platform RV Endeavor
DOI: 10.6084/m9.figshare.7007693
title: Complete_data_healthhui.xlsx from A liver health hui: hepatitis C knowledge and associated risk factors in New Zealand gang members and their families

description: Hepatitis C virus (HCV) and B virus (HBV) infections are highly prevalent, with a high percentage of undiagnosed cases. Knowledge of HCV and its modes of transmission are essential for disease prevention and management. We studied a high-risk New Zealand gang population on viral hepatitis prevalence, their level of knowledge and the liver health risk factors in a community setting. Participants completed demographic, risk factor and knowledge questionnaires in three health meetings in New Zealand. Participants' blood samples were tested for HBV, HCV, biochemical indicators of liver disease. Liver fibrosis levels were assessed using a Fibroscan<sup>®</sup> device. We studied 52 adult Mongrel Mob members, affiliates and whānau (extended family) throughout New Zealand. We identified no HCV and two HBV cases, confirmed high-risk factors levels and poor associated knowledge, with a significant association between lack of knowledge and presence of specific risk factors. We successfully conducted a community-focused, high-risk, hard-to-reach gang population study, and found a link between lack of knowledge and risk factors for HCV infection. This study provided first-of-its-kind data on viral hepatitis in a gang population and demonstrated the need for educational screening programmes to aid early HCV detection, prevention and treatment.
DOI: 10.6084/m9.figshare.7007693.v1
title: Complete_data_healthhui.xlsx from A liver health hui: hepatitis C knowledge and associated risk factors in New Zealand gang members and their families

description: Hepatitis C virus (HCV) and B virus (HBV) infections are highly prevalent, with a high percentage of undiagnosed cases. Knowledge of HCV and its modes of transmission are essential for disease prevention and management. We studied a high-risk New Zealand gang population on viral hepatitis prevalence, their level of knowledge and the liver health risk factors in a community setting. Participants completed demographic, risk factor and knowledge questionnaires in three health meetings in New Zealand. Participants' blood samples were tested for HBV, HCV, biochemical indicators of liver disease. Liver fibrosis levels were assessed using a Fibroscan<sup>®</sup> device. We studied 52 adult Mongrel Mob members, affiliates and whānau (extended family) throughout New Zealand. We identified no HCV and two HBV cases, confirmed high-risk factors levels and poor associated knowledge, with a significant association between lack of knowledge and presence of specific risk factors. We successfully conducted a community-focused, high-risk, hard-to-reach gang population study, and found a link between lack of knowledge and risk factors for HCV infection. This study provided first-of-its-kind data on viral hepatitis in a gang population and demonstrated the need for educational screening programmes to aid early HCV detection, prevention and treatment.
DOI: 10.7284/107245
title: Multiplexed data collected during research cruise EN508 using a Hawaii UHDAS instrument system onboard the platform RV Endeavor
DOI: 10.7284/112012
title: GNSS (Global Navigation Satellite System) data collected during research cruise EN514 using a Trimble NT-300D instrument system onboard the platform RV Endeavor
DOI: 10.6084/m9.figshare.7007552
title: a-Synuclein short MD simulations:homo-A53T

description: Short molecular dynamics simulations of a-Synuclein amyloids, homo-A53T<br>
DOI: 10.6084/m9.figshare.7007552.v1
title: a-Synuclein short MD simulations:homo-A53T

description: Short molecular dynamics simulations of a-Synuclein amyloids, homo-A53T<br>
DOI: 10.6084/m9.figshare.7007543
title: Chronologie des dépôts de brevets relatifs aux SDN

description: Corpus de 141 familles de brevets relatives aux stimulateurs des défenses naturelles des plantes (SDN), obtenu par interrogation en novembre 2007 de la base <i>Derwent World Patents Index</i>. L'abrégé Derwent (une version à valeur ajoutée de l'abrégé par défaut du brevet) de chacune de ces familles de brevets décrit explicitement un effet SDN.
DOI: 10.6084/m9.figshare.7007543.v1
title: Chronologie des dépôts de brevets relatifs aux SDN

description: Corpus de 141 familles de brevets relatives aux stimulateurs des défenses naturelles des plantes (SDN), obtenu par interrogation en novembre 2007 de la base <i>Derwent World Patents Index</i>. L'abrégé Derwent (une version à valeur ajoutée de l'abrégé par défaut du brevet) de chacune de ces familles de brevets décrit explicitement un effet SDN.
DOI: 10.6084/m9.figshare.7007537
title: Chronologie des dépôts de brevets relatifs au Bion®

description: Corpus de 168 familles de brevets relatives au Bion®, obtenu par interrogation en novembre 2007 de la base <i>Derwent World Patents Index</i> par mot-clé, nomenclature chimique et numéro <i>CAS Registry</i>. Il cherche à rendre compte du développement du Bion® dans la stratégie de Syngenta, de ses concurrents ou des laboratoires de recherche.
DOI: 10.6084/m9.figshare.7007534
title: Supplementary Material for: Zinc Alleviates Lipopolysaccharide Interference with Both Body Temperature and Sickness Behavior in Virgin Female Rats

description: <b><i>Objectives:</i></b> Previous studies from our group<b><i></i></b> showed that lipopolysaccharide (LPS) exposure induces several signs of sickness behavior, including a decrease in food consumption, body weight gain, adipsia, and a biphasic effect in tympanic temperature with a first phase of hypothermia, followed by an increased tympanic temperature. LPS can activate a chain of nonspecific host responses, including the immune response, and decreased zinc levels. In addition, there are differences in the immune response between males and females, particularly fever, with sex hormones interfering with body temperature. This study aims to characterize the effects of zinc treatment on tympanic temperature, body weight gain, food and water consumption, and general activity in open field of virgin female rats exposed to a dose of LPS that was previously reported to induce sickness behavior. <b><i>Methods:</i></b> Virgin female Wistar rats were treated with either saline (S) or LPS. One hour later, the S group received another injection of saline (S + S group), half of the LPS group received saline (LPS + S group) and the other half received zinc (LPS + Zn group). Tympanic temperature, body weight, and water and food consumption were measured for 96 h. Measurements and observations started 2 h after LPS administration. <b><i>Results:</i></b> Treatment with zinc attenuated LPS-increased temperature, decreased the body weight gain and food consumption, and water consumption was increased. <b><i>Conclusion:</i></b> Zinc treatment is beneficial as it reduces the increased tympanic temperature induced by LPS, but it does not influence other sickness behavior caused by exposure to LPS.
DOI: 10.6084/m9.figshare.7007537.v2
title: Chronologie des dépôts de brevets relatifs au Bion®

description: Corpus de 168 familles de brevets relatives au Bion®, obtenu par interrogation en novembre 2007 de la base <i>Derwent World Patents Index</i> par mot-clé, nomenclature chimique et numéro <i>CAS Registry</i>. Il cherche à rendre compte du développement du Bion® dans la stratégie de Syngenta, de ses concurrents ou des laboratoires de recherche.
DOI: 10.6084/m9.figshare.7007531
title: a-Synuclein short MD simulations:WT

description: Short molecular dynamics simulations of a-Synuclein amyloids, WT
DOI: 10.6084/m9.figshare.7007537.v1
title: Corpus de 168 familles de brevets relatives au Bion®

description: Corpus de 168 familles de brevets relatives au Bion®, obtenu par interrogation en novembre 2007 de la base <i>Derwent World Patents Index</i> par mot-clé, nomenclature chimique et numéro <i>CAS Registry</i>. Il cherche à rendre compte du développement du Bion® dans la stratégie de Syngenta, de ses concurrents ou des laboratoires de recherche.
DOI: 10.6084/m9.figshare.7007531.v2
title: a-Synuclein short MD simulations:WT

description: Short molecular dynamics simulations of a-Synuclein amyloids, WT
DOI: 10.6084/m9.figshare.7007531.v1
title: a-Synuclein short MD simulations:WT

description: Short molecular dynamics simulations of a-Synuclein amyloids, WT
DOI: 10.7284/112001
title: GNSS (Global Navigation Satellite System) data collected during research cruise EN525 using a Trimble NT-300D instrument system onboard the platform RV Endeavor
DOI: 10.6084/m9.figshare.7007492
title: Liste des PME actives dans le domaine des SDN en France et à l'étranger

description: Liste aussi exhaustive que possible des PME actives dans le domaine des stimulateurs des défenses naturelles des plantes (SDN) en France et à l'étranger, en date de 2007, avec un exemple de leur produit commercialisé ou en cours d'étude.
DOI: 10.6084/m9.figshare.7007492.v1
title: Liste des PME actives dans le domaine des SDN en France et à l'étranger

description: Liste aussi exhaustive que possible des PME actives dans le domaine des stimulateurs des défenses naturelles des plantes (SDN) en France et à l'étranger, en date de 2007, avec un exemple de leur produit commercialisé ou en cours d'étude.
DOI: 10.6084/m9.figshare.7007483
title: More business as usual? Explaining business bias across issues and institutions in the European Union

description: Business interest groups numerically dominate the European Union (EU) interest group communities. However, scholars note that the relative proportion of business interests varies by either the institutional venue or the policy issue. Exchange-theoretical approaches emphasize the distinct informational needs of policy-makers at different venues, hereby favoring business actors to a varying degree. Other scholars emphasize the importance of conflict and argue that containment or expansion of conflict on concrete policy issues shapes the relative presence of business interest representatives. We simultaneously test both hypotheses comparing interest group activities on seventy issues observed in the European Parliament, the European Commission and in the EU media. We find little differences between the EU venues in terms of the interests represented. Rather, the salience and scope of issues seem more important denominators for variation in business lobby activity.
DOI: 10.6084/m9.figshare.7007483.v1
title: More business as usual? Explaining business bias across issues and institutions in the European Union

description: Business interest groups numerically dominate the European Union (EU) interest group communities. However, scholars note that the relative proportion of business interests varies by either the institutional venue or the policy issue. Exchange-theoretical approaches emphasize the distinct informational needs of policy-makers at different venues, hereby favoring business actors to a varying degree. Other scholars emphasize the importance of conflict and argue that containment or expansion of conflict on concrete policy issues shapes the relative presence of business interest representatives. We simultaneously test both hypotheses comparing interest group activities on seventy issues observed in the European Parliament, the European Commission and in the EU media. We find little differences between the EU venues in terms of the interests represented. Rather, the salience and scope of issues seem more important denominators for variation in business lobby activity.
DOI: 10.6084/m9.figshare.7007486
title: Discovery of (phenylureido)piperidinyl benzamides as prospective inhibitors of bacterial autolysin E from <i>Staphylococcus aureus</i>

description: Autolysin E (AtlE) is a cell wall degrading enzyme that catalyzes the hydrolysis of the β-1,4-glycosidic bond between the <i>N</i>-acetylglucosamine and <i>N</i>-acetylmuramic acid units of the bacterial peptidoglycan. Using our recently determined crystal structure of AtlE from <i>Staphylococcus aureus</i> and a combination of pharmacophore modeling, similarity search, and molecular docking, a series of (Phenylureido)piperidinyl benzamides were identified as potential binders and surface plasmon resonance (SPR) and saturation-transfer difference (STD) NMR experiments revealed that discovered compounds bind to AtlE in a lower micromolar range. (phenylureido)piperidinyl benzamides are the first reported non-substrate-like compounds that interact with this enzyme and enable further study of the interaction of small molecules with bacterial AtlE as potential inhibitors of this target.