cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q2gh9mzj
title: BindingDB Entry 50006353: Design, Synthesis, and Evaluation of Orally Available Clioquinol-Moracin M Hybrids as Multitarget-Directed Ligands for Cognitive Improvement in a Rat Model of Neurodegeneration in Alzheimer's Disease.

description: Small molecule binding data for protein 3',5'-cyclic phosphodiesterase, Uniprot A0A140VJR0 and Q08499
DOI: 10.7270/q23b6349
title: BindingDB Entry 50006357: Design and synthesis of 2-oxindole based multi-targeted inhibitors of PDK1/Akt signaling pathway for the treatment of glioblastoma multiforme.

description: Small molecule binding data for protein 3-phosphoinositide dependent protein kinase-1, Axin-1/Glycogen synthase kinase-3 beta, Glycogen synthase kinase-3, and Serine/threonine-protein kinase Chk1/2, Uniprot A0A024R0L5, O14757, O15530, P49840, P49841, and Q6FI27
DOI: 10.7270/q2736tx4
title: BindingDB Entry 50006356: Development of new highly potent imidazo[1,2-b]pyridazines targeting Toxoplasma gondii calcium-dependent protein kinase 1.

description: Small molecule binding data for protein Cyclin-Dependent Kinase 5 (CDK5), Glycogen synthase kinase-3, Receptor-interacting serine/threonine-protein kinase 3, and Serine/threonine-protein kinase haspin, Uniprot A0A090N7W4, B2LUN4, I6LNT8, Q00535, Q15078, Q8TF76, and Q9Y572
DOI: 10.7270/q2zk5knm
title: BindingDB Entry 50006358: Structural Elucidation of a Small Molecule Inhibitor of Protein Disulfide Isomerase.

description: Small molecule binding data for protein Protein Disulfide-Isomerase (PDI), Uniprot A0A024R8S5 and P07237
DOI: 10.7270/q2k93bjf
title: BindingDB Entry 50006362: Anion and sulfonamide inhibition studies of an α-carbonic anhydrase from the Antarctic hemoglobinless fish Chionodraco hamatus.

description: Small molecule binding data for protein Carbonic anhydrase and Carbonic anhydrases; II & IX, Uniprot P00915, P00918, P07451, V9HW21, V9HWA3, and V9HWE3
DOI: 10.7270/q2q2437q
title: BindingDB Entry 50006361: Potent complement C3a receptor agonists derived from oxazole amino acids: Structure-activity relationships.

description: Small molecule binding data for protein C3a anaphylatoxin chemotactic receptor, Uniprot A8K2H7 and Q16581
DOI: 10.7270/q2tt4txw
title: BindingDB Entry 50006360: Enzyme kinetics and inhibition of histone acetyltransferase KAT8.

description: Small molecule binding data for protein HIF1A/p300/CREB-binding protein and Histone acetyltransferase KAT8, Uniprot Q09472 and Q9H7Z6
DOI: 10.7270/q2fn195j
title: BindingDB Entry 50006363: A selective delta opioid receptor antagonist based on a stilbene core.

description: Small molecule binding data for protein Delta-type opioid receptor, Uniprot P41143
DOI: 10.7270/q2639sqv
title: BindingDB Entry 50006366: Benzo[7]annulene-based GluN2B selective NMDA receptor antagonists: Surprising effect of a nitro group in 2-position.

description: Small molecule binding data for protein GluN1/GluN2B NMDA receptor, Glutamate receptor ionotropic, NMDA 2B, and Sigma-1 receptor, Uniprot Q05586, Q13224, and Q60492
DOI: 10.7270/q29w0jg8
title: BindingDB Entry 50006364: Discovery of potent, selective, and orally bioavailable inhibitors of interleukin-1 receptor-associate kinase-4.

description: Small molecule binding data for protein Interleukin-1 receptor-associated kinase 1, Interleukin-1 receptor-associated kinase 4, and Mitogen-activated protein kinase kinase kinase 7, Uniprot O43318, P51617, Q69FE3, and Q9NWZ3
DOI: 10.7270/q22b920x
title: BindingDB Entry 50006367: Identification and optimisation of a series of tetrahydrobenzotriazoles as metabotropic glutamate receptor 5-selective positive allosteric modulators that improve performance in a preclinical model of cognition.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2 and D(2) dopamine receptor/Metabotropic glutamate receptor 5, Uniprot P40989 and P41594
DOI: 10.7270/q2st7stz
title: BindingDB Entry 50006371: 1H-Pyrazolo[3,4-g]hexahydro-isoquinolines as potent GR antagonists with reduced hERG inhibition and an improved pharmacokinetic profile.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2 and Glucocorticoid receptor, Uniprot F1D8N4, P04150, P06536, and P40989
DOI: 10.7270/q2xk8jh7
title: BindingDB Entry 50006370: Design of Specific Serine Protease Inhibitors Based on a Versatile Peptide Scaffold: Conversion of a Urokinase Inhibitor to a Plasma Kallikrein Inhibitor.

description: Small molecule binding data for protein Coagulation factor X and plasma kallikrein, Coagulation factor XI, Hepatocyte growth factor activator/Serine protease hepsin/Suppressor of tumorigenicity 14 protein, Kallikrein 1, Plasma kallikrein, Plasminogen, Thrombin, Thrombin and coagulation factor X, Tissue-type plasminogen activator, Trypsin I, Urokinase-type plasminogen activator (uPA), Urokinase-type plasminogen activator/surface receptor, and Vitamin K-dependent protein C, Uniprot A0A024QZM9, A0A1R3UCD2, P00734, P00747, P00749, P00750, P00760, P03951, P03952, P04070, P06869, P06870, P11214, P19221, P20918, P26262, Q0VBA8, Q3TJ94, and Q9Y5Y6
DOI: 10.7270/q2p2724s
title: BindingDB Entry 50006372: Synthesis, cyclooxygenase inhibition, anti-inflammatory evaluation and ulcerogenic liability of novel triarylpyrazoline derivatives as selective COX-2 inhibitors.

description: Small molecule binding data for protein Prostaglandin E synthase/G/H synthase 2 and Prostaglandin G/H synthase (cyclooxygenase), Uniprot P05979 and P35354
DOI: 10.7270/q2jd50sx
title: BindingDB Entry 50006373: Design and synthesis of an in vivo-efficacious PIM3 kinase inhibitor as a candidate anti-pancreatic cancer agent.

description: Small molecule binding data for protein Axin-1/Glycogen synthase kinase-3 beta, Death-associated protein kinase 1, Serine/threonine-protein kinase pim-1, Serine/threonine-protein kinase pim-2, and Serine/threonine-protein kinase pim-3, Uniprot A0A024QYW7, A0A024RD25, P11309, P49841, P53355, Q6FI27, Q86V86, and Q9P1W9
DOI: 10.7270/q2dn482m
title: BindingDB Entry 50006374: Microwave-assisted solid-phase synthesis of side-chain to side-chain lactam-bridge cyclic peptides.

description: Small molecule binding data for protein Melanocortin receptor 1, Melanocortin receptor 3, Melanocortin receptor 4, and Melanocortin receptor 5, Uniprot A0A0B6VTJ4, P33033, P41149, P56450, Q01727, and Q544G7
DOI: 10.7270/q28w3h9f
title: BindingDB Entry 50006375: Discovery and Pharmacology of a Novel Class of Diacylglycerol Acyltransferase 2 Inhibitors.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2, Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A, Diacylglycerol O-acyltransferase 1, Diacylglycerol O-acyltransferase 2, Glycerol-3-phosphate acyltransferase 1, mitochondrial, and Voltage-gated calcium channel, Uniprot C1ID52, O60840, O75907, P08684, P10635, P11712, P40989, Q10469, Q54AA6, Q6GRK0, Q921V5, Q96PD7, Q9HCL2, Q9Z2A7, and S5RV20
DOI: 10.7270/q2542rk1
title: BindingDB Entry 50006376: Development of Alkyne-Containing Pyrazolopyrimidines To Overcome Drug Resistance of Bcr-Abl Kinase.

description: Small molecule binding data for protein Bcr-Abl and Cereblon/BCR/ABL, Uniprot A0A024R8E2, P00519, and P11274
DOI: 10.7270/q21c20vp
title: BindingDB Entry 50006377: Benzazaborinines as Novel Bioisosteric Replacements of Naphthalene: Propranolol as an Example.

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 1A, 5-hydroxytryptamine receptor 2A, 5-hydroxytryptamine receptor 2B, 5-hydroxytryptamine receptor 2C, 5-hydroxytryptamine receptor 6, 5-hydroxytryptamine receptor 7, Adenosine receptor A1/Alpha-2A adrenergic receptor, Adenosine receptor A2a, Adenosine receptor A3, Adrenergic receptor, Angiotensin II receptor, Cholecystokinin receptor, Cytochrome P450 1A, Cytochrome P450 2C19, Cytochrome P450 2C8, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A, D(2) dopamine receptor, Delta-type opioid receptor, Dopamine D1 and D2 receptor, Endothelin receptor, ET-A/ET-B, Kappa-type opioid receptor, Mu-type opioid receptor, Muscarinic acetylcholine receptor M1 and M3, Muscarinic acetylcholine receptor M2 and M5, Serotonin (5-HT) receptor, and Vasopressin receptor, Uniprot A0A024R3C5, A0A024R3W1, A4D1Q0, C1ID52, P05177, P07550, P08172, P08588, P08684, P08908, P08913, P0DMS8, P10632, P10635, P11229, P11712, P14416, P18825, P20309, P21728, P25101, P28222, P28223, P28335, P29274, P30556, P32238, P33261, P34969, P35348, P35372, P37288, P41143, P41145, P41595, P50406, Q4W594, Q53XZ3, Q53YY0, Q5ZGX3, Q6GRK0, S5RV20, X5D2B0, X5D7I5, X5DNB4, and X5DQM5
DOI: 10.7270/q2rx9g2v
title: BindingDB Entry 50006380: A structure-activity relationship of non-peptide macrocyclic histone deacetylase inhibitors and their anti-proliferative and anti-inflammatory activities.

description: Small molecule binding data for protein Cereblon/Histone deacetylase 1, Cereblon/Histone deacetylase 6, and Histone deacetylase 8, Uniprot A0A024QZ26, Q13547, Q6IT96, Q9BY41, and Q9UBN7
DOI: 10.7270/q2wm1hf9
title: BindingDB Entry 50006378: 2,30-Bis(10H-indole) heterocycles: New p53/MDM2/MDMX antagonists.

description: Small molecule binding data for protein MDM2-MDMX, Uniprot O15151 and Q00987
DOI: 10.7270/q2n58qcw
title: BindingDB Entry 50006381: Synthesis and comparison of the biological activity of monocyclic phosphonate, difluorophosphonate and phosphate analogs of the natural AChE inhibitor cyclophostin.

description: Small molecule binding data for protein Acetylcholinesterase and Cholinesterases; ACHE & BCHE, Uniprot P22303 and Q7YWJ9
DOI: 10.7270/q2hd7zpm
title: BindingDB Entry 50006382: Discovery of novel quinoline-based mTOR inhibitors via introducing intra-molecular hydrogen bonding scaffold (iMHBS): The design, synthesis and biological evaluation.

description: Small molecule binding data for protein PIK3CG/PIK3R1, Phosphatidylinositol 3-kinase regulatory subunit beta/Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform/gamma isoform, and mTOR/FKBP12A/FKBP12B, Uniprot A0A024R720, A0A2K8FKV1, O00329, P42336, P42338, P42345, and P48736
DOI: 10.7270/q2cn76xt
title: BindingDB Entry 50006383: Modification of a dihydropyrrolopyrimidine phosphoinositide 3-kinase (PI3K) inhibitor to improve oral bioavailability.

description: Small molecule binding data for protein Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial, Uniprot P42336
DOI: 10.7270/q27w6g6h
title: BindingDB Entry 50006385: Design, synthesis and evaluation of antiestrogen and histone deacetylase inhibitor molecular hybrids.

description: Small molecule binding data for protein Baculoviral IAP repeat-containing protein 2/Estrogen receptor, Cereblon/Histone deacetylase 6, and Histone deacetylase 3, Uniprot A0A024QZ26, G4XH65, O15379, P03372, and Q9UBN7
DOI: 10.7270/q2445qg3
title: BindingDB Entry 50006386: Design, synthesis and preliminary biological studies of pyrrolidine derivatives as Mcl-1 inhibitors.

description: Small molecule binding data for protein Apoptosis regulator Bcl-2/Bcl-2 homologous antagonist/killer, Bcl-xL/Bcl-2-binding component 3, and MCL1-BAK1 complex, Uniprot A0A024R2B3, A0A0S2Z3C5, P10415, Q07817, and Q07820
DOI: 10.7270/q20c4zst
title: BindingDB Entry 50006387: Synthesis and SAR of Imidazo[1,5-a]pyridine derivatives as 5-HT4 receptor partial agonists for the treatment of cognitive disorders associated with Alzheimer's disease.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2, Cytochrome P450 2D6, Cytochrome P450 3A, Serotonin (5-HT) receptor, Serotonin 4 (5-HT4) receptor, and Serotonin receptor 2a and 2b (5HT2A and 5HT2B), Uniprot A0A2D3FAF9, C1ID52, O70528, P08684, P10635, P30994, P40989, Q13639, Q62758, and Q6GRK0
DOI: 10.7270/q2qz2dz2
title: BindingDB Entry 50006389: Novel Series of Dihydropyridinone P2X7 Receptor Antagonists.

description: Small molecule binding data for protein Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A, P2X purinoceptor 1, P2X purinoceptor 4, P2X purinoceptor 5, P2X purinoceptor 7, and P2X2/3, Uniprot C1ID52, P08684, P10635, P11712, P51575, P56373, Q64663, Q6GRK0, Q93086, Q99571, Q99572, Q9UBL9, and S5RV20
DOI: 10.7270/q2vq35nb
title: BindingDB Entry 50006388: Novel hydrazone moiety-bearing aminopyrimidines as selective inhibitors of epidermal growth factor receptor T790M mutant.

description: Small molecule binding data for protein Epidermal growth factor receptor and MER intracellular domain/EGFR extracellular domain chimera, Uniprot P00533, P04626, P21860, Q15303, and X5DNK3
DOI: 10.7270/q2m61p8h
title: BindingDB Entry 50006390: Antibacterial Prenylated Acylphloroglucinols from Psorothamnus fremontii.

description: Small molecule binding data for protein Cytochrome P450 11A1, Uniprot P14137
DOI: 10.7270/q2bp05s0
title: BindingDB Entry 50006393: 5-Aryl-1-imino-1-oxo-[1,2,4]thiadiazines.

description: Small molecule binding data for protein Beta-secretase (BACE), Uniprot A0A024R3D7 and P56817
DOI: 10.7270/q2gf0xhb
title: BindingDB Entry 50006391: Multicomponent reaction-based synthesis and biological evaluation of tricyclic heterofused quinolines with multi-trypanosomatid activity.

description: Small molecule binding data for protein Acetylcholinesterase, Uniprot O42275
DOI: 10.7270/q26w9f24
title: BindingDB Entry 50006394: Thioxo-dihydroquinazolin-one Compounds as Novel Inhibitors of Myeloperoxidase.

description: Small molecule binding data for protein Myeloperoxidase and Xanthine dehydrogenase, Uniprot P05164 and P47989
DOI: 10.7270/q2348pdm
title: BindingDB Entry 50006395: Design, Synthesis, and Biological Evaluation of 1,2-Dihydroisoquinolines as HIV-1 Integrase Inhibitors.

description: Small molecule binding data for protein Integrase, Uniprot F2WR39,F2WR52,Q76353
DOI: 10.7270/q2tq64kv
title: BindingDB Entry 50006397: Targeting the Src Homology 2 (SH2) Domain of Signal Transducer and Activator of Transcription 6 (STAT6) with Cell-Permeable, Phosphatase-Stable Phosphopeptide Mimics Potently Inhibits Tyr641 Phosphorylation and Transcriptional Activity.

description: Small molecule binding data for protein Signal transducer and activator of transcription 6, Uniprot P42226
DOI: 10.7270/q2zg6w79
title: BindingDB Entry 50006396: Synthesis and Evaluation of Novel Erlotinib-NSAID Conjugates as More Comprehensive Anticancer Agents.

description: Small molecule binding data for protein MER intracellular domain/EGFR extracellular domain chimera, Prostaglandin E synthase/G/H synthase 2, and Prostaglandin G/H synthase (cyclooxygenase), Uniprot P00533, P05979, and P35354
DOI: 10.7270/q2k64n3p
title: BindingDB Entry 50006399: Design and synthesis of fused tetrahydroisoquinoline-iminoimidazolines.

description: Small molecule binding data for protein Adenosine receptor A2a, Uniprot P29274 and X5DNB4
DOI: 10.7270/q2ff3wcz
title: BindingDB Entry 50006400: Highly functionalized tetrahydropyridines are cytotoxic and selective inhibitors of human puromycin sensitive aminopeptidase.

description: Small molecule binding data for protein Aminopeptidase and Aminopeptidase N, Uniprot P15145 and P55786
DOI: 10.7270/q29p34nm
title: BindingDB Entry 50006401: Spiroindole Alkaloids and Spiroditerpenoids from Aspergillus duricaulis and Their Potential Neuroprotective Effects.

description: Small molecule binding data for protein Beta amyloid A4 protein, Uniprot A0A140VJC8 and P05067
DOI: 10.7270/q2280bm6
title: BindingDB Entry 50006406: Development of a potent and selective cell penetrant Legumain inhibitor.

description: Small molecule binding data for protein Caspase, Caspase-3, Cathepsin (B and K), Cathepsin (S and K), Legumain, and Ubiquitin carboxyl-terminal hydrolase 17, Uniprot A0A024R374, P07858, P25774, P42574, Q14790, Q53XC6, Q6R6M4, and Q99538
DOI: 10.7270/q25x2czb
title: BindingDB Entry 50006404: Synthesis and biological evaluation of negative allosteric modulators of the Kv11.1(hERG) channel.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2, Uniprot P40989
DOI: 10.7270/q2xg9v5t
title: BindingDB Entry 50006407: Flavones Inhibit the Activity of AKR1B10, a Promising Therapeutic Target for Cancer Treatment.

description: Small molecule binding data for protein Aldo-keto reductase family member 1B10 (AKR1B10) and Aldose reductase, Uniprot A0A024R7A8, O60218, and P15121
DOI: 10.7270/q2sq93d1
title: BindingDB Entry 50006408: Synthesis and biological evaluation of novel 5-(hydroxamic acid)methyl oxazolidinone derivatives.

description: Small molecule binding data for protein Amine oxidase (flavin-containing) A and Amine oxidase [flavin-containing] B, Uniprot P21397, P27338, and Q53YE7
DOI: 10.7270/q2nz8bnv
title: BindingDB Entry 50006409: Resveratrol-Related Polymethoxystilbene Glycosides: Synthesis, Antiproliferative Activity, and Glycosidase Inhibition.

description: Small molecule binding data for protein Beta-galactosidase, Uniprot Q2U7N3
DOI: 10.7270/q2j67kxf
title: BindingDB Entry 50006410: Synthesis, biological activity evaluation and molecular docking studies of novel coumarin substituted thiazolyl-3-aryl-pyrazole-4-carbaldehydes.

description: Small molecule binding data for protein Cytochrome P450 2A6, Uniprot P11509
DOI: 10.7270/q2df6v64
title: BindingDB Entry 50006411: Novel orally active inhibitors of β-1,3-glucan synthesis derived from enfumafungin.

description: Small molecule binding data for protein Beta-1,3-glucan synthase, Uniprot O13383
DOI: 10.7270/q28p63jp
title: BindingDB Entry 50006412: Structure activity relationships of 4-hydroxy-2-pyridones: A novel class of antituberculosis agents.

description: Small molecule binding data for protein Cytochrome P450 2C9, Cytochrome P450 2D6, and Cytochrome P450 3A, Uniprot C1ID52, P08684, P10635, P11712, Q6GRK0, and S5RV20
DOI: 10.7270/q2514270
title: BindingDB Entry 50006413: Analogues of ethionamide, a drug used for multidrug-resistant tuberculosis, exhibit potent inhibition of tyrosinase.

description: Small molecule binding data for protein Tyrosinase, Uniprot O42713
DOI: 10.7270/q21839jq
title: BindingDB Entry 50006414: Identification and activity of inhibitors of the essential nematode-specific metalloprotease DPY-31.

description: Small molecule binding data for protein Zinc metalloproteinase dpy-31, Uniprot A0A0C5PRQ1, A0A4E9F4X4,A0A5S6PQA5, and A8Q2D1
DOI: 10.7270/q2rr227r
title: BindingDB Entry 50006419: Structure-activity relationship studies of pyrimidine-2,4-dione derivatives as potent P2X7 receptor antagonists.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2 and P2X purinoceptor 7, Uniprot P40989 and Q99572
DOI: 10.7270/q2wh2t0j
title: BindingDB Entry 50006418: Discovery of AZ0108, an orally bioavailable phthalazinone PARP inhibitor that blocks centrosome clustering.

description: Small molecule binding data for protein Poly [ADP-ribose] polymerase 1, Poly [ADP-ribose] polymerase 2, Poly [ADP-ribose] polymerase 6, Protein mono-ADP-ribosyltransferase PARP3, and Tankyrase 1/2, Uniprot A0A024R318, A0A024R3T8, A0A024R5Z4, O95271, P09874, Q2NL67, Q9H2K2, Q9UGN5, and Q9Y6F1
DOI: 10.7270/q2n019hb
title: BindingDB Entry 50006422: Development of a Highly Potent D2/D3 Agonist and a Partial Agonist from Structure-Activity Relationship Study of N(6)-(2-(4-(1H-Indol-5-yl)piperazin-1-yl)ethyl)-N(6)-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine Analogues: Implication in the Treatment of Parkinson's Disease.

description: Small molecule binding data for protein D(2) dopamine receptor, D(3) dopamine receptor, Dopamine D2 receptor and Serotonin 2a receptor (D2 and 5HT2a), and Dopamine receptor D2 and D3, Uniprot A0A024R3C5, P14416, P19020, P35462, and P61169
DOI: 10.7270/q2cf9t36
title: BindingDB Entry 50006425: Benzoxazolone Carboxamides as Potent Acid Ceramidase Inhibitors: Synthesis and Structure-Activity Relationship (SAR) Studies.

description: Small molecule binding data for protein Acid ceramidase, Uniprot Q13510
DOI: 10.7270/q2h70jsm
title: BindingDB Entry 50006424: Discovery of a marine-derived bis-indole alkaloid fascaplysin, as a new class of potent P-glycoprotein inducer and establishment of its structure-activity relationship.

description: Small molecule binding data for protein Cyclin-dependent kinase 4, Uniprot A0A024RBB6 and P11802
DOI: 10.7270/q241713m
title: BindingDB Entry 50006431: Discovery and SAR of Novel and Selective Inhibitors of Urokinase Plasminogen Activator (uPA) with an Imidazo[1,2-a]pyridine Scaffold.

description: Small molecule binding data for protein Coagulation factor X and plasma kallikrein, Plasminogen, Thrombin and coagulation factor VII, Thrombin and coagulation factor X, Tissue-type plasminogen activator, and Urokinase-type plasminogen activator/surface receptor, Uniprot A0A024QZM9, P00734, P00742, P00747, P00749, P00750, P03952, P08709, and Q5JVE7
DOI: 10.7270/q27s7rss
title: BindingDB Entry 50006427: Identification, synthesis and pharmacological evaluation of novel anti-EV71 agents via cyclophilin A inhibition.

description: Small molecule binding data for protein Peptidyl-prolyl cis-trans isomerase A, Uniprot P62937 and V9HWF5
DOI: 10.7270/q20868bf
title: BindingDB Entry 50006434: Arthroamide, a Cyclic Depsipeptide with Quorum Sensing Inhibitory Activity from Arthrobacter sp.

description: Small molecule binding data for protein Accessory gene regulator protein A, Uniprot P0A0I7 and Q309Y7
DOI: 10.7270/q2qr514t
title: BindingDB Entry 50006438: Synthesis and biological evaluation of picolinamides and thiazole-2-carboxamides as mGluR5 (metabotropic glutamate receptor 5) antagonists.

description: Small molecule binding data for protein D(2) dopamine receptor/Metabotropic glutamate receptor 5, Uniprot P41594
DOI: 10.7270/q2vh5rvr
title: BindingDB Entry 50006435: Searching for novel applications of the benzohomoadamantane scaffold in medicinal chemistry: Synthesis of novel 11β-HSD1 inhibitors.

description: Small molecule binding data for protein 11-beta-hydroxysteroid dehydrogenase, Uniprot P28845 and X5D2L1
DOI: 10.7270/q2g73hrk
title: BindingDB Entry 50006441: Discovery of substituted-2,4-dimethyl-(naphthalene-4-carbonyl)amino-benzoic acid as potent and selective EP4 antagonists.

description: Small molecule binding data for protein Cytochrome P450 1A, Cytochrome P450 2B6, Cytochrome P450 2C19, Cytochrome P450 2C8, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A, and Prostaglandin E2 receptor, Uniprot C1ID52, P05177, P08684, P10632, P10635, P11712, P20813, P33261, P34995, P35408, P43115, P43116, Q6GRK0, and S5RV20
DOI: 10.7270/q2m048fv
title: BindingDB Entry 50006440: Identification of novel protein tyrosine phosphatase sigma inhibitors promoting neurite extension.

description: Small molecule binding data for protein Receptor-type tyrosine-protein phosphatase S, Uniprot Q13332
DOI: 10.7270/q2bk1gcp
title: BindingDB Entry 50006445: Cross metathesis with hydroxamate and benzamide BOC-protected alkenes to access HDAC inhibitors and their biological evaluation highlighted intrinsic activity of BOC-protected dihydroxamates.

description: Small molecule binding data for protein Cereblon/Histone deacetylase 1, Cereblon/Histone deacetylase 2, Cereblon/Histone deacetylase 6, and Histone deacetylase 3, Uniprot A0A024QZ26, O15379, Q13547, Q6IT96, Q92769, and Q9UBN7
DOI: 10.7270/q2319zwj
title: BindingDB Entry 50006449: Identification of dual PPARα/γ agonists and their effects on lipid metabolism.

description: Small molecule binding data for protein Peroxisome proliferator-activated receptor, Uniprot F1D8S4, P37231, and Q07869