cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.24566669
title: An ultrastructural report of human articular cartilage resident cells in correlation with their phenotypic characteristics

description: The recent discovery of progenitors based on their differential fibronectin-adhesion (FAA-CPs) and migratory-based (MCPs) assay has evoked interest due to their superiority in terms of their efficient chondrogenesis and reduced hypertrophic propensity. This study aims to isolate and enrich three articular cartilage subsets, chondrocytes, FAA-CPs, and MCPs, and compare their undifferentiated and chondrogenic differentiated status, using in-vitro phenotypical characterization in correlation with ultrastructural analysis using Transmission Electron Microscopy (TEM). Following informed consent, cartilage shavings were procured from a non-diseased human ankle joint and cultured to obtain the three subsets. Chondrocytes exhibited higher CD106 and lower CD49b and CD146 levels. Following chondrogenic differentiation, corroborative results were seen, with the MCP group showing the highest GAG/DNA ratio levels and uptake of extracellular matrix stain as compared to the FAA-CP group. TEM analysis of the chondrocytes revealed the presence of more autolytic cells with disintegrated cytoplasm and plasma membrane. The differentiated FAA-CPs and MCPs displayed higher collagen and rough endoplasmic reticulum. The results presented in this study provide novel information on the ultrastructural characteristics of cartilage resident cells, with the chondrocyte group displaying features of terminal differentiation. Both progenitor subtypes showed superiority in varied contexts, with greater collagen fibrils and greater GAG content in MCPs. The display of preferential and differentiation traits sheds insight on the necessity to enrich progenitors and coculturing them with the general pool of constituent cells to combine their advantages and reduce their drawbacks to achieve a regenerative tissue displaying genuine hyaline-like repair while limiting their terminal differentiation.
DOI: 10.6084/m9.figshare.24566669.v1
title: An ultrastructural report of human articular cartilage resident cells in correlation with their phenotypic characteristics

description: The recent discovery of progenitors based on their differential fibronectin-adhesion (FAA-CPs) and migratory-based (MCPs) assay has evoked interest due to their superiority in terms of their efficient chondrogenesis and reduced hypertrophic propensity. This study aims to isolate and enrich three articular cartilage subsets, chondrocytes, FAA-CPs, and MCPs, and compare their undifferentiated and chondrogenic differentiated status, using in-vitro phenotypical characterization in correlation with ultrastructural analysis using Transmission Electron Microscopy (TEM). Following informed consent, cartilage shavings were procured from a non-diseased human ankle joint and cultured to obtain the three subsets. Chondrocytes exhibited higher CD106 and lower CD49b and CD146 levels. Following chondrogenic differentiation, corroborative results were seen, with the MCP group showing the highest GAG/DNA ratio levels and uptake of extracellular matrix stain as compared to the FAA-CP group. TEM analysis of the chondrocytes revealed the presence of more autolytic cells with disintegrated cytoplasm and plasma membrane. The differentiated FAA-CPs and MCPs displayed higher collagen and rough endoplasmic reticulum. The results presented in this study provide novel information on the ultrastructural characteristics of cartilage resident cells, with the chondrocyte group displaying features of terminal differentiation. Both progenitor subtypes showed superiority in varied contexts, with greater collagen fibrils and greater GAG content in MCPs. The display of preferential and differentiation traits sheds insight on the necessity to enrich progenitors and coculturing them with the general pool of constituent cells to combine their advantages and reduce their drawbacks to achieve a regenerative tissue displaying genuine hyaline-like repair while limiting their terminal differentiation.
DOI: 10.6084/m9.figshare.20382376
title: Comparison of mini percutaneous nephrolithotomy and standard percutaneous nephrolithotomy for renal stones &gt;2cm: a systematic review and meta-analysis

description: ABSTRACT Background The purpose is to compare the efficacy and safety of mini percutaneous nephrolithotomy (mini-PCNL) versus standard percutaneous nephrolithotomy (standard-PCNL) in patients with renal stones &gt;2cm. Materials and Methods A systematic literature search was conducted in PubMed, Web of Science, Scopus, and the Cochrane Library databases to identify relevant studies before March 8, 2021. Stone-free rate (SFR), operation time, fever rate, hemoglobin drop, blood transfusion rate, and hospitalization time were used as outcomes to compare mini-PCNL and standard-PCNL. The meta-analysis was performed using the Review Manager version 5.4. Results Seven randomized controlled trials were included in our meta-analysis, involving 1407 mini-PCNL cases and 1436 standard-PCNL cases. Our results reveal that, for renal stones &gt;2cm, mini-PCNL has a similar SFR (risk ratio (RR)=1.01, 95% confidence interval (CI): 0.98 to 1.04, p=0.57) and fever rate (RR=1.22, 95% CI: 0.97-1.51, p=0.08). Standard-PCNL was associated with a significantly shorter operating time (weighted mean difference (WMD)=8.23, 95% CI: 3.44 to 13.01, p &lt;0.01) and a longer hospitalization time (WMD=-20.05, 95% CI: -29.28 to -10.81, p &lt;0.01) than mini-PCNL. Subgroup analysis showed hemoglobin drop and blood transfusion for 30F standard-PCNL were more common than mini-PCNL (WMD=-0.95, 95% CI: -1.40 to -0.50, p &lt;0.01; RR=0.20, 95% CI: 0.07 to 0.58, p &lt;0.01). Conclusion In the treatment of &gt;2cm renal stones, mini-PCNL should be considered an effective and reliable alternative to standard-PCNL (30F). It achieves a comparable SFR to standard-PCNL, but with less blood loss, lower transfusion rate, and shorter hospitalization. However, the mini-PCNL does not show a significant advantage over the 24F standard-PCNL. On the contrary, this procedure takes a longer operation time. Trial registration This meta-analysis was reported consistent with the PRISMA statement and was registered on PROSPERO, with registration number 2021CRD42021234893.
DOI: 10.6084/m9.figshare.20382376.v1
title: Comparison of mini percutaneous nephrolithotomy and standard percutaneous nephrolithotomy for renal stones &gt;2cm: a systematic review and meta-analysis

description: ABSTRACT Background The purpose is to compare the efficacy and safety of mini percutaneous nephrolithotomy (mini-PCNL) versus standard percutaneous nephrolithotomy (standard-PCNL) in patients with renal stones &gt;2cm. Materials and Methods A systematic literature search was conducted in PubMed, Web of Science, Scopus, and the Cochrane Library databases to identify relevant studies before March 8, 2021. Stone-free rate (SFR), operation time, fever rate, hemoglobin drop, blood transfusion rate, and hospitalization time were used as outcomes to compare mini-PCNL and standard-PCNL. The meta-analysis was performed using the Review Manager version 5.4. Results Seven randomized controlled trials were included in our meta-analysis, involving 1407 mini-PCNL cases and 1436 standard-PCNL cases. Our results reveal that, for renal stones &gt;2cm, mini-PCNL has a similar SFR (risk ratio (RR)=1.01, 95% confidence interval (CI): 0.98 to 1.04, p=0.57) and fever rate (RR=1.22, 95% CI: 0.97-1.51, p=0.08). Standard-PCNL was associated with a significantly shorter operating time (weighted mean difference (WMD)=8.23, 95% CI: 3.44 to 13.01, p &lt;0.01) and a longer hospitalization time (WMD=-20.05, 95% CI: -29.28 to -10.81, p &lt;0.01) than mini-PCNL. Subgroup analysis showed hemoglobin drop and blood transfusion for 30F standard-PCNL were more common than mini-PCNL (WMD=-0.95, 95% CI: -1.40 to -0.50, p &lt;0.01; RR=0.20, 95% CI: 0.07 to 0.58, p &lt;0.01). Conclusion In the treatment of &gt;2cm renal stones, mini-PCNL should be considered an effective and reliable alternative to standard-PCNL (30F). It achieves a comparable SFR to standard-PCNL, but with less blood loss, lower transfusion rate, and shorter hospitalization. However, the mini-PCNL does not show a significant advantage over the 24F standard-PCNL. On the contrary, this procedure takes a longer operation time. Trial registration This meta-analysis was reported consistent with the PRISMA statement and was registered on PROSPERO, with registration number 2021CRD42021234893.
DOI: 10.21227/8a7n-kt84
title: IEEEXtreme 13: Ranged Alfa Pool

description: This dataset contains a total of 1289 submissions, with 6% correct solutions and 12% partial solutions. Link to the original challenge: https://csacademy.com/ieeextreme-practice/task/ranged-alfa-pool/ See the included PDF document for details about the original challenge.
DOI: 10.6084/m9.figshare.8323760
title: Role of <i>Wdr45b</i> in maintaining neural autophagy and cognitive function

description: Macroautophagy/autophagy functions as a quality control mechanism by degrading misfolded proteins and damaged organelles and plays an essential role in maintaining neural homeostasis. The phosphoinositide phosphatidylinositol-3-phosphate (PtdIns3P) effector Atg18 is essential for autophagosome formation in yeast. Mammalian cells contain four Atg18 homologs, belonging to two subclasses, WIPI1 (WD repeat domain, phosphoinositide interacting 1), WIPI2 and WDR45B/WIPI3 (WD repeat domain 45B), WDR45/WIPI4. The role of <i>Wdr45b</i> in autophagy and in neural homeostasis, however, remains unknown. Recent human genetic studies have revealed a potential causative role of <i>WDR45B</i> in intellectual disability. Here we demonstrated that mice deficient in <i>Wdr45b</i> exhibit motor deficits and learning and memory defects. Histological analysis reveals that <i>wdr45b</i> knockout (KO) mice exhibit a large number of swollen axons and show cerebellar atrophy. SQSTM1- and ubiquitin-positive aggregates, which are autophagy substrates, accumulate in various brain regions in <i>wdr45b</i> KO mice. Double KO mice, <i>wdr45b</i> and <i>wdr45</i>, die within one day after birth and exhibit more severe autophagy defects than either of the single KO mice, suggesting that these two genes act cooperatively in autophagy. Our studies demonstrated that WDR45B is critical for neural homeostasis in mice. The <i>wdr45b</i> KO mice provide a model to study the pathogenesis of intellectual disability. <b>Abbreviations</b>: ACSF: artificial cerebrospinal fluid; AMC: aminomethylcoumarin; BPAN: beta-propeller protein-associated neurodegeneration; CALB1: calbindin 1; CNS: central nervous system; DCN: deep cerebellar nuclei; fEPSP: field excitatory postsynaptic potential; IC: internal capsule; ID: intellectual disability; ISH: <i>in situ</i> hybridization; KO: knockout; LTP: long-term potentiation; MBP: myelin basic protein; MGP: medial globus pallidus; PtdIns3P: phosphoinositide phosphatidylinositol-3-phosphate; WDR45B: WD repeat domain 45B; WIPI1: WD repeat domain, phosphoinositide interacting 1; WT: wild type.
DOI: 10.6084/m9.figshare.8323760.v1
title: Role of <i>Wdr45b</i> in maintaining neural autophagy and cognitive function

description: Macroautophagy/autophagy functions as a quality control mechanism by degrading misfolded proteins and damaged organelles and plays an essential role in maintaining neural homeostasis. The phosphoinositide phosphatidylinositol-3-phosphate (PtdIns3P) effector Atg18 is essential for autophagosome formation in yeast. Mammalian cells contain four Atg18 homologs, belonging to two subclasses, WIPI1 (WD repeat domain, phosphoinositide interacting 1), WIPI2 and WDR45B/WIPI3 (WD repeat domain 45B), WDR45/WIPI4. The role of <i>Wdr45b</i> in autophagy and in neural homeostasis, however, remains unknown. Recent human genetic studies have revealed a potential causative role of <i>WDR45B</i> in intellectual disability. Here we demonstrated that mice deficient in <i>Wdr45b</i> exhibit motor deficits and learning and memory defects. Histological analysis reveals that <i>wdr45b</i> knockout (KO) mice exhibit a large number of swollen axons and show cerebellar atrophy. SQSTM1- and ubiquitin-positive aggregates, which are autophagy substrates, accumulate in various brain regions in <i>wdr45b</i> KO mice. Double KO mice, <i>wdr45b</i> and <i>wdr45</i>, die within one day after birth and exhibit more severe autophagy defects than either of the single KO mice, suggesting that these two genes act cooperatively in autophagy. Our studies demonstrated that WDR45B is critical for neural homeostasis in mice. The <i>wdr45b</i> KO mice provide a model to study the pathogenesis of intellectual disability. <b>Abbreviations</b>: ACSF: artificial cerebrospinal fluid; AMC: aminomethylcoumarin; BPAN: beta-propeller protein-associated neurodegeneration; CALB1: calbindin 1; CNS: central nervous system; DCN: deep cerebellar nuclei; fEPSP: field excitatory postsynaptic potential; IC: internal capsule; ID: intellectual disability; ISH: <i>in situ</i> hybridization; KO: knockout; LTP: long-term potentiation; MBP: myelin basic protein; MGP: medial globus pallidus; PtdIns3P: phosphoinositide phosphatidylinositol-3-phosphate; WDR45B: WD repeat domain 45B; WIPI1: WD repeat domain, phosphoinositide interacting 1; WT: wild type.
DOI: 10.5281/zenodo.10724414
title: Supplemental Material: Computational Experiments in Computer Science Research: A Literature Survey

description: This laboratory package contains supplemental material from the study: "Supplemental Material: Computational Experiments in Computer Science Research: A literature survey". The supplementary material contains:1. The .xlsx file of the dataset used to analyze the RQs.2. The list of figures published in the scientific article.
DOI: 10.5281/zenodo.10724415
title: Supplemental Material: Computational Experiments in Computer Science Research: A Literature Survey

description: This laboratory package contains supplemental material from the study: "Supplemental Material: Computational Experiments in Computer Science Research: A literature survey". The supplementary material contains:1. The .xlsx file of the dataset used to analyze the RQs.2. The list of figures published in the scientific article.
DOI: 10.6084/m9.figshare.14615213.v1
title: Additional file 1 of The fecal microbiota of patients with pancreatic ductal adenocarcinoma and autoimmune pancreatitis characterized by metagenomic sequencing

description: Additional file 1: Table S1. Statistics for the Illumina metagenomic sequencing data.
DOI: 10.6084/m9.figshare.14615213
title: Additional file 1 of The fecal microbiota of patients with pancreatic ductal adenocarcinoma and autoimmune pancreatitis characterized by metagenomic sequencing

description: Additional file 1: Table S1. Statistics for the Illumina metagenomic sequencing data.
DOI: 10.21227/m2ms-0413
title: IEEEXtreme 13: Xranda and Tree

description: This dataset contains a total of 4624 submissions, with 3% correct solutions and 9% partial solutions. Link to the original challenge: https://csacademy.com/ieeextreme-practice/task/xranda-and-tree/ See the included PDF document for details about the original challenge.
DOI: 10.5281/zenodo.10713630
title: Common Training and Testing data for Machine Learning Models in PNW
DOI: 10.5281/zenodo.10713631
title: Common Training and Testing data for Machine Learning Models in PNW
DOI: 10.5281/zenodo.10724379
title: Common Training and Testing data for Machine Learning Models in PNW
DOI: 10.6084/m9.figshare.14615216
title: Additional file 2 of The fecal microbiota of patients with pancreatic ductal adenocarcinoma and autoimmune pancreatitis characterized by metagenomic sequencing

description: Additional file 2: Table S2. Denovo assembly of high-quality metagenomic shotgun sequencing data.
DOI: 10.6084/m9.figshare.14615216.v1
title: Additional file 2 of The fecal microbiota of patients with pancreatic ductal adenocarcinoma and autoimmune pancreatitis characterized by metagenomic sequencing

description: Additional file 2: Table S2. Denovo assembly of high-quality metagenomic shotgun sequencing data.
DOI: 10.6084/m9.figshare.14615219
title: Additional file 3 of The fecal microbiota of patients with pancreatic ductal adenocarcinoma and autoimmune pancreatitis characterized by metagenomic sequencing

description: Additional file 3: Table S3. Differentially enriched gut microbiota at every level between groups using MetaPhlAn2 method. Taxon with a p. adj &lt; 0.2 (FDR-corrected Kruskal–Wallis test) were shown. FDR-corrected Kruskal–Wallis test was followed by Steel–Dwass test for pairwise comparisons. Threshold of p-value (Steel–Dwass test) was set at 0.05.
DOI: 10.6084/m9.figshare.14615219.v1
title: Additional file 3 of The fecal microbiota of patients with pancreatic ductal adenocarcinoma and autoimmune pancreatitis characterized by metagenomic sequencing

description: Additional file 3: Table S3. Differentially enriched gut microbiota at every level between groups using MetaPhlAn2 method. Taxon with a p. adj &lt; 0.2 (FDR-corrected Kruskal–Wallis test) were shown. FDR-corrected Kruskal–Wallis test was followed by Steel–Dwass test for pairwise comparisons. Threshold of p-value (Steel–Dwass test) was set at 0.05.
DOI: 10.6084/m9.figshare.14615221
title: Additional file 3 of KDM6A-ARHGDIB axis blocks metastasis of bladder cancer by inhibiting Rac1

description: Additional file 3.
DOI: 10.25549/whit-c170-57208
title: Doctor Voice working, Southern California, 1934

description: Photographic portrait of Doctor Voice, Southern California, 1934. "Subject: Doctor Voice working; Client: Theradophilus; Agency: Heintz-Peckering Co[mpany], 323 W. 6th St[ree]t-Ed Martin; Original Print Order: 1; Size: 5x7; Finish: gl[ossy]; Mount: M[oun]t[e]d; Job: 8-22-117; Year: 1934" -- on envelope front. "Operator's Report Name: Dick; 1 Original Photographs-At Studio: 5x7; Amount: 15.00; Extra Charges: #572" -- on envelope back. "Original, Order, Heintz-Pickering & Co[mpany], 562 Paramount B[ui]ld[in]g, This NUMBER MUST appear on INVOICE, No. 572, To: Dick Whittington, Date: August 22, 1934, Client: Therapy, L[imi]t[e]d, Date Wanted, Confirming order of Mr. E. E. Martin, 1 photo of man to be used for Theradophilus mail order ad in Physical Culture, For Use in, Heintz Pickering & Co[mpany], By eem/cp" -- order front.
DOI: 10.15468/dl.t1kgp5
title: Occurrence Download

description: A dataset containing 68692 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Russian Federation",
 "Geometry POLYGON((22.75 49.14,22.75 59.37,50.44 59.37,50.44 49.14,22.75 49.14))",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 68692 records from 181 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0073198-160910150852091/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.25549/whit-c170-95167
title: Scenes from play, Southern California, 1940

description: 23 photographs of scenes from a play, Southern California, 1940. "Subject: Scenes from a play, 2 [ilg]; Client: Pilgrimage Play, Hal Weiner; Classifications: 8/12/40; Original Print Order: 1 #5, 2, 5, 20, 1 #11, 2#10, 16, 1 #19; Size: 8x10; Finish: gl[ossy], dull; Year: 1940; Job: 07-3-13" -- on envelope front. "23 Original Photographs - Size: 12 - 11x14 gl[ossy], 11 - 8x10 gl[ossy]; 21 @ 2, 2 @ 2.50; 12 - 11x14 @ 25¢ extra; Amount: 50" -- on envelope back.
DOI: 10.15468/dl.psengf
title: Occurrence Download

description: A dataset containing 329 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Curcuma L.",
 "Country is Australia"
 ]
}

 The dataset includes 329 records from 7 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0073203-160910150852091/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.25549/whit-c170-61210
title: Group watching advancing prices, 52 Birthday Sale, Southern California, 1933

description: 5 photographic portraits of boy, man, and women, Southern California, 1933. "Subject: Group watching advancing prices, 52 Birthday Sale; Client: May Co.; Original Print Order: 1 ea[ch]; Size: 8x10; Finish: gl[ossy]; Year: 1933; Job: 6-13-50" -- on envelope front. "Operator's Report Name: Dick; 5 Original Photographs-- At Studio: 8x10, incl[uding] models & artwork; Amount: $30.00; Extra Charges: Bishop" -- on envelope back.
DOI: 10.25549/whit-c170-95072
title: 2nd Ford after 500 miles, Southern California, 1940

description: 10 photographs of 2nd Ford motor after 500 miles, Southern California, 1940. "2nd Ford after 500 miles; Client: Calif[ornia] Testing Laboratories; Original Print Order: Wed[nesday] a.m., 1 ea[ch]; Size: 8x10; Finish: gl[ossy]; Year: 1940; Job: 07-2-10" -- on envelope front. "Operator's Report - Name: Joe; 10 Original Photographs - Size; total neg[ative]s 142; Amount: 25.00" -- on envelope back.
DOI: 10.15468/dl.dphpwj
title: Occurrence Download

description: A dataset containing 168 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Curcuma L.",
 "Country is Myanmar"
 ]
}

 The dataset includes 168 records from 6 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0073205-160910150852091/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.25549/whit-c170-63546
title: Christmas roto book, Bullock's, Southern California, 1933

description: 22 photographs of Bullock's Christmas items, Southern California, 1933. "Subject: Xmas roto book; Client: Bullock's; Original Print Order: 1 ea[ch]; Size: contact; Finish: gloss[y]; Job: 11-14-81-D; Year: 1933" -- on envelope front. "Original Photographs-Size: Charged in 11-14-81-A" -- on envelope back.
DOI: 10.15468/dl.gfj9ss
title: Occurrence Download

description: A dataset containing 1202 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Carcharodon carcharias (Linnaeus, 1758)"
 ]
}

 The dataset includes 1202 records from 88 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0073382-160910150852091/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.25549/whit-c170-83533
title: Wrecked Studebaker & Chrysler, Iveson vs. Baller, Southern California, 1935

description: 5 photographs of two wrecked automobiles, Southern California, 1935. "Subject: Wrecked Studebaker & Chrysler, Iveson vs. Baller; Client: Helen Callaway, 920 Bartlett B[ui]ld[in]g, Mi 9301. Mr. Baker; Original Print Order: 1 ea[ch]; Size: 8x10; Finish: gl[ossy]; Year: 1935; Job: 11-14-83" -- on envelope front. "Operator's Report Name: Beegle; 5 Original Photographs--Size: 8x10 Int[eriors]; Amount: 11=; 1 Ounces of Flash Powder" -- on envelope back.
DOI: 10.25549/whit-c170-4801
title: Mr. Hughes residence, Cypress Street, Covina, CA, 1925

description: Photograph of exterior of house, Cypress Street, Covina, CA, 1925. "Subject: Mr. Hughes residence, Cypress St[reet], Covina" -- on envelope.
DOI: 10.15468/dl.vnaoay
title: Occurrence Download

description: A dataset containing 12 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Boesenbergia Kuntze",
 "Country is China"
 ]
}

 The dataset includes 12 records from 4 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0073221-160910150852091/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.25549/whit-c170-4266
title: 190 North Freeman Street, Hawthorne, CA, 1925

description: 2 photographs of the exterior of 190 North Freeman Street, Hawthorne, CA, 1925. "Subject: 190 No[rth] Freeman St[reet], Hawthorne; Client: W. Dwight Hammond; Year: 1925; Job: 7-31-75" -- on envelope.