cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.25957306.v1
title: PDTC improves cognitive impairment in LPS-induced ARDS by regulating miR-181c/NF-κB axis-mediated neuroinflammation

description: Cognitive impairment is a severe complication of acute respiratory distress syndrome (ARDS). Emerging studies have revealed the effects of pyrrolidine dithiocarbamate (PDTC) on improving surgery-induced cognitive impairment. The major aim of the study was to investigate whether PDTC protected against ARDS-induced cognitive dysfunction and to identify the underlying mechanisms involved. The rat model of ARDS was established by intratracheal instillation of lipopolysaccharide (LPS), followed by treatment with PDTC. The cognitive function of rats was analyzed by the Morris Water Maze, and pro-inflammatory cytokines were assessed by quantitative real-time PCR, enzyme-linked immunosorbent assay, and western blot assays. A dual-luciferase reporter gene assay was performed to identify the relationship between miR-181c and its target gene, <i>TAK1 binding protein 2 (TAB2)</i>. The results showed that PDTC improved cognitive impairment and alleviated neuroinflammation in the hippocampus in LPS-induced ARDS model. Furthermore, we demonstrated that miR-181c expression was downregulated in the hippocampus of the ARDS rats, which was restored by PDTC treatment. In vitro studies showed that miR-181c alleviated LPS-induced pro-inflammatory response by inhibiting TAB2, a critical molecule in the nuclear factor (NF)-κB signaling pathway. PDTC improves cognitive impairment in LPS-induced ARDS by regulating miR-181c/NF-κB axis-mediated neuroinflammation, providing a potential opportunity for the treatment of this disease.
DOI: 10.15151/esrf-es-2013334370
title: Exploring the dynamic nature of OCP crystals by combined use of diffraction and in crystallo spectrophotometry at room-temperature

description: The photoactive Orange Carotenoid Protein (OCP) is a reversible photoswitch which serves photoprotection in cyanobacteria (Wilson et al. 2006). OCP is
functionalized by a keto-carotenoid pigment which, in the presence of a blue-green photon, is able to induce conformational changes resulting in a photoactivated
state capable of quenching an excess of absorbed light energy. Preliminary experiments offered first evidence that dehydration of OCP crystals lead to the trapping of
a pre-activated state. The very goal of our experiment is to verify this hypothesis by simultaneous collection of diffraction and spectroscopic data from crystals at
room-temperature and at varied levels of humidity
DOI: 10.15151/esrf-es-2004447730
title: Jahn-Teller distortions in La1-xSrxCo1-yNiyO3-d perovskites

description: We suppose that accurate temperature dependent high-resolution X-ray powder diffraction (XPD) measurements in order to study an effects associated with Jahn-Teller (JT) distortions in La1-xSrxCo1-yNiyO3-d.
The combination of XPD results with our neutron diffraction [10] and Co K-edge XMCD data will give us the opportunity to establish the correlations between crystal and magnetic structure changes and clarify the origin of magneto-structural phase transition near the paramagnetic -&gt;ferromagnetic -&gt;antiferromagnetic transitions, as well as to provide an input for a novel modeling methods based on the density functional theory (DFT, DFT+U, DFT+U+SO) and the dynamic mean-field theory (DFT+DMFT). The calculations will allow us to gain new fundamental insights into the nature of AFM to FM phase transition by clarifying spin-states in each phase, i.e. compare of the Co3+(HS) + Co4+(IS) into Co3+(HS-&gt;IS-&gt;LS) + growth of cooperative JT effect Co4+(LS) or dynamic JT Co2+(LS) [9-11].
DOI: 10.15151/esrf-es-2031230634
title: scanning diffraction tests on synthetic Egyptian Blue samples

description: nano-beam scanning diffraction tests on synthetic Egyptian Blue samples
DOI: 10.6084/m9.figshare.25880135
title: Prevalence of tinnitus following non-blast related traumatic brain injury: a systematic review of literature

description: To establish the prevalence of tinnitus in adults who have sustained non-blast related traumatic brain injury (TBI), as well as the prevalence of tinnitus following TBI in the absence of hearing loss. A systematic search was carried out using MEDLINE, EMBASE, PsycINFO, CINAHL from January 1st 1990 to August 14th 2023. TBI, tinnitus and auditory findings were extracted from all eligible studies, and a descriptive synthesis performed. This systematic review was registered with PROSPERO (Registration number: CRD42022377637). Based on the Oxford Centre of Evidence-Based Medicine (OCEBM) (2011) criteria, the highest quality evidence identified was at Level 2b, with the bulk of the included studies predominantly populating the lower evidence tiers. While there was a substantial variability in the methods used to establish and report the presence of tinnitus, its occurrence following TBI was evident in adults with and without hearing loss. The need for prospective, longitudinal research into tinnitus following non-blast related TBI is evident. Such comprehensive studies hold the potential to inform and enhance the clinical diagnosis and management of this patient population.
DOI: 10.6084/m9.figshare.25880135.v1
title: Prevalence of tinnitus following non-blast related traumatic brain injury: a systematic review of literature

description: To establish the prevalence of tinnitus in adults who have sustained non-blast related traumatic brain injury (TBI), as well as the prevalence of tinnitus following TBI in the absence of hearing loss. A systematic search was carried out using MEDLINE, EMBASE, PsycINFO, CINAHL from January 1st 1990 to August 14th 2023. TBI, tinnitus and auditory findings were extracted from all eligible studies, and a descriptive synthesis performed. This systematic review was registered with PROSPERO (Registration number: CRD42022377637). Based on the Oxford Centre of Evidence-Based Medicine (OCEBM) (2011) criteria, the highest quality evidence identified was at Level 2b, with the bulk of the included studies predominantly populating the lower evidence tiers. While there was a substantial variability in the methods used to establish and report the presence of tinnitus, its occurrence following TBI was evident in adults with and without hearing loss. The need for prospective, longitudinal research into tinnitus following non-blast related TBI is evident. Such comprehensive studies hold the potential to inform and enhance the clinical diagnosis and management of this patient population.
DOI: 10.15151/esrf-es-2003417825
title: Emphasizing Substrate Registry and Orientation in Crystallographic Studies of MOF and COF Thin Films

description: Metal-organic frameworks (MOFs) and covalent organic frameworks (COFs) are pivotal in molecular separation, catalysis, and energy storage due to their
distinctive structures. Our proposal focuses on MOF and COF thin films, aiming to explore the limits of these materials. We've developed a novel 2D film MOF
and COF class, showing exceptional separation performance. Our breakthrough in crystallization has led to single-unit-cell thick 2D zeolitic imidazolate framework
(ZIF) films with superior hydrogen flux. We've also prepared Zn2(bim)4 and UiO-66-NH2 MOF films, and extended our methods to 2D COF films, demonstrating
impressive separation capabilities. Access to the BM01 synchrotron facility for GIXRD will allow detailed analysis of crystal structures and effects of solvent
annealing and guest molecules on film structure. We aim to further investigate UiO-66 derivatives for selective NH3 separation, contributing to renewable energy
solutions.
DOI: 10.15151/esrf-es-2002917053
title: Coupling oxidation state and catalyst stability during pulsed electrochemical CO2 reduction via operando X-ray absorption spectroscopy

description: Electrochemical CO2 reduction (eCO2R) is a promising pathway to convert detrimental CO2 emissions into sustainable chemicals. The use of gas diffusion electrodes (GDEs) fed by gaseous CO2 enables achieving high activity and selectivity, albeit with limited stability. We recently demonstrated by operando wide-angle X-rays scattering that, during continuous electrolysis, (bi)carbonate crystals precipitate close to the catalyst, causing GDE instability. Strikingly, preliminary pulsed electrolysis experiments show that (bi)carbonate precipitation can take place without losses of GDE selectivity, leading to a 10-fold increase in GDE stability. As the catalyst can oxidize during the pulses, we propose to use operando X-rays absorption spectroscopy to investigate the role of catalyst oxidation state in controlling GDE selectivity and stability during pulsed electrolysis, as this holds the key to stable eCO2R.
DOI: 10.15151/esrf-es-2002918174
title: Determining the material time of an aging metallic glass - relation of dynamics and structure

description: Glasses are off-equilibrium materials that slowly relax towards their meta-stable equilibrium state, which is referred to as physical aging. Physical aging is known to be a highly non-linear process with regard to temperature history. The physical origin of this non-linearity has been proposed decades ago within the famous material time concept. Recently, this conjecture has been confirmed by some of the authors for an aging molecular glass, by the first-time experimental determination of the material time, which was then shown to, e.g., linearize the change of the material's dielectric properties during aging. The proposal aims to extend the material time concept to metallic glasses, by XPCS experiments. Moreover, simultaneous structural characterizations offer the unique opportunity of verifying whether the material time, determined from dynamical properties of the material, does linearize the change of the material's structure during aging.
DOI: 10.15151/esrf-es-2002918892
title: Proof of principle experiment for demonstrating high-resolution computed tomography ghost-imaging x-ray fluorescence

description: X-ray fluorescence computed tomography (XRF-CT) is an important imaging technique that provides three-dimensional chemical maps. It can be used in many fields for example, to study the distribution of trace elements in biological tissues, to map the distribution of metal ions in materials, or to study the distribution of contrast agents in medical imaging. Despite its success XRF-CT faces several challenges related to the requirement to focus the incident beam and raster scan the sample. Our proposal centres around a proof-of-principle experiment aimed at demonstrating the potential of applying an innovative technique called Ghost Imaging (GI) to XRF-CT. This experimental endeavour underscores several significant advantages that distinguish it from conventional raster scan imaging approaches:
DOI: 10.15151/esrf-es-2002919217
title: Understanding the rare earths distribution of Geochemistry in Clarion-Clipperton Zone Polymetallic Nodules at the nanoscale

description: Polymetallic nodules and hardgrounds, spread across vast abyssal plains, rich in Fe, Mn, Ni, Co, Cu, and REE and yttrium (REY), result from metal precipitation in the ocean due to erosion or hydrothermal emissions. Clarion-Clipperton Zone's polymetallic nodules boast concentrations of up to 2800 ppm REY, making them promising alternative sources for rare earth supply. However, uncertainties persist regarding REY enrichment mechanisms resulting in strong variations in Ce anomalies. Biogenic fluorapatite and Fe-Mn oxy-hydroxides are acknowledged Ce scavengers, yet their enrichment mechanisms remain under-explained. These experiments will pioneer μXRF and μXANES measurements, illuminating the distribution of Ce3+ and Ce4+ in Clarion-Clipperton polymetallic nodules. Furthermore, the acquired data will serve as a proxy to subsequently investigate and comprehend the mechanisms underlying the accumulation of Ce and REY in polymetallic nodules and hardgrounds found in Spanish waters.
DOI: 10.15151/esrf-es-2002919516
title: Structure-activity relationships of homogeneous Pd species in high-pressure diene-CO2 reactions forming carbon-fixating monomers

description: This proposal aims to shed light on the Pd-catalyzed reaction of novel conjugated dienes with CO2. Recently, several new dienes were synthesized in our group, widening the potential scope of this reaction. The synthesis of cyclic monoesters with these dienes would provide a wide variety of building blocks for polyesters with high CO2 fixation capacity. To achieve high product yields for different types of dienes, more insights in (i) the catalytic cycle, (ii) structure-activity relationships and (iii) the main deactivation routes are required. These aspects have not yet been properly investigated using relevant characterization techniques (e.g. XAS, NMR, IR) due to the challenging reactions conditions, such as high CO2 pressure. The proposed experiment aims to fill this gap, focusing on the characterization of the Pd catalysts under industrially relevant temperature and CO2 pressure, employing an ad hoc designed high-pressure catalytic cell.
DOI: 10.15151/esrf-es-2001353901
title: In situ study of the reactivity of Calcium Carbonate polymorphs and aluminosilicates during hydration of low-clinker LC3 cement pastes

description: To pursue the 2050 global Net Neutrality goal, cement industry (producing the most used material worldwide but also emitting about 6% of the global CO2) has to find groundbreaking strategies to reduce the cement and concrete impact. Addingreactive non-cementitious materials to cement formulations is a very promising way to improve the sustainability of construction and building materials. Composite formulations of Cement, Limestone and Calcined Clay (LC3 cements) or pozzolans-based cements, where non-cementitious phases may reach 45% wt.,show synergistic effects between CaCO3 and aluminosilicates. However, aspects as polymorphisms, particle shape and size, aspect ratio and surface activity are expected to play a relevant role are still unstudied.
Using in situ s3DXRD e Phase Contrast Tomography (PCT) during LC3 cement hydration can provide a deep insight on the effects of the above mentioned aspects evident to us, up to now, by X-ray diffraction, 27Al/29Si SS NMR and TG/DSC studies.
DOI: 10.15151/esrf-es-2003357538
title: Nanoscopic 3D axon morphology in the normal and diseased human brain

description: The pathways of the brain control the speed of saltatory conduction by means of the micrometer-sized axons. The larger axons the faster the signal conduction along the axon. Holotomography imaging at ID16A showed that axons in the monkey brain visualized in 3D are not cylinder-like as assumed today but form a distribution of diameters along the axon. Human 3D axon morphology has not been explored. Selected pathways with different functions will give new insights into how 3D axon morphology adapts to the need for speed. It will provide validation data for in vivo 3D Magnetic Resonance Imaging (MRI) axon models to explain why a larger population of large axons is detected by MRI but not supported by 2D histology. Further, we will shed light on a novel hypothesis that neurodegenerative diseases may attack different axon diameter populations by quantifying the 3D morphology of known attacked pathways in a diseased brain to be compared with a healthy brain.
DOI: 10.15151/esrf-es-2000216609
title: Unveiling Copper Adaptation Mechanisms in Bacteria: Insights from Bufferin-Copper Complexes via X-ray Absorption Spectroscopy

description: A necessary metal that is toxic in excess, copper induces adaptive responses in bacteria. Bacterial resistance or tolerance to this agent has thus become a problem in healthcare and agriculture. We identified a new mechanism for copper adaptation based on post-translationally modified peptides called ‘bufferins’ that enhance bacterial growth in the presence of excess copper, through the formation of complexes with copper. Our objective is to exploit X-ray Absorption Spectroscopy to investigate the copper binding site of bufferins in order to gain insight into what is likely to become a new path toward bacterial resistance.
DOI: 10.15151/esrf-es-2000217284
title: Following dislocation structures at a penetrable grain boundary during cyclic loading

description: This proposal aims at investigating the 3D damage evolution during first stage fatigue near a penetrable grain boundary in micron-sized copper cantilevers. To do so, we will combine the recent 3D- μLaue technique of BM32 with the users’ in situ micro-deformation capabilities, to measure cyclically loaded Cu bi-crystals. The X-ray microscope will provide 3D microstructural quantities (local strains, dislocations densities, etc.) with high spatial resolution (&lt; 0.5 µm) relevant to understand the interaction mechanisms between dislocations and grain boundaries, which will help formulating mechanism-based material laws.
DOI: 10.15151/esrf-es-2003362800
title: Uncovering nuclear quantum effects in superionic ice at extreme P-T conditions

description: We aim to extend our investigations on superionic water ice under extreme pressure and temperature, following proposals HC-4677 and HC-5078. Previously, we implemented a novel sample assembly enabling efficient laser-heating of confined H2O in the diamond anvil cell, revealing a remarkable volume thermal expansion of fcc ice indicative of superionic conduction. Discrepancies between advanced ab-initio calculations and experiments suggest nuclear quantum effects influence. We propose studying deuterated ice (D2O) to explore this further. These measurements have the potential to challenge ab-initio calculations. It should also help refine icy planetary interior models and deepen our understanding of hydrogen bonds in extreme conditions.
DOI: 10.15151/esrf-es-1999196779
title: RIXS study of spontaneously forming superstructures in the thiospinel CuIr2S4

description: The thiospinel CuIr2S4 is discussed as an outstanding example for the spontaneous formation of complex superstructures (octamers) below a metal-insulator transition. The mechanism is still controversial. Theories range from an itinerant picture of an orbitally induced Peierls transition, neglec¬ting spin-orbit coupling, to local models in which spin-orbit coupling and intersite Coulomb repulsion are decisive. In preliminary RIXS data, we found evidence for dimers in the metallic phase at 300 K, a very unexpected result. We propose a thorough RIXS study to clarify the origin of superstructures in this fascinating material, e.g. establishing whether the dimerisation is intrinsic or a remnant of the insulating phase.
DOI: 10.15151/esrf-es-1999197477
title: A combined XAS/XES investigation of photochemically-driven water capture and release in azopyridine-appended metal-organic frameworks

description: Water scarcity is one of the key contemporary environmental issues. Metal Organic Frameworks (MOFs) have emerged as unique materials for atmospheric water harvesting even at very low relative humidity levels, with facile uptake and release kinetics. In order to rationally design improved water harvesting MOFs it is however critical to reach a detailed mechanistic, structural, and electronic understanding of the dynamic adsorption-desorption process. Here, we propose a combined in situ hard XAS/XES study to investigate the local structural and electronic modifications that occur during water adsorption and desorption in MOF systems appended with azopyridine molecules that undergo photochemically induced cis/trans transitions, which regulate the water uptake and release. We expect our results to unveil the stages of water capture by selected MOFs with unprecedented detail, thereby paving the way for the rational design of improved MOF water harvesting systems.
DOI: 10.15468/dl.ugsmdj
title: Occurrence Download

description: A dataset containing 126 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Athyma jina Moore, 1857"
 ]
}

 The dataset includes 126 records from 23 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0011077-250127130748423/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.8348321
title: Datasets and scripts of the study "The Spread of the Yellow Ribbon in Twitter: Agent-based Simulation of a Complex Contagion Process"

description: Datasets and scripts of the study "The Spread of the Yellow Ribbon in Twitter: Agent-based Simulation of a Complex Contagion Process"
DOI: 10.5281/zenodo.8348322
title: Datasets and scripts of the study "The Spread of the Yellow Ribbon in Twitter: Agent-based Simulation of a Complex Contagion Process"

description: Datasets and scripts of the study "The Spread of the Yellow Ribbon in Twitter: Agent-based Simulation of a Complex Contagion Process"
DOI: 10.15468/dl.4a7hv3
title: Occurrence Download

description: A dataset containing 200 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Unkana ambasa (Moore, 1857)"
 ]
}

 The dataset includes 200 records from 8 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0011078-250127130748423/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.nbryzc
title: Occurrence Download

description: A dataset listing the 34 species recorded in GBIF matching the query:
{
 "and" : [
 "Year is 2010",
 "TaxonKey is Litoria Tschudi, 1838"
 ]
}

 The dataset's 34 records were derived from 24 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0011076-250127130748423/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.6exux7
title: Occurrence Download

description: A dataset containing 70 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Year is 1900",
 "TaxonKey is Vulpes vulpes (Linnaeus, 1758)"
 ]
}

 The dataset includes 70 records from 21 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0011079-250127130748423/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.14457/tu.the.2024.109
title: Production rescheduling with machine breakdown based on data collection from IOT system

description: Job shop scheduling is critical to manufacturing optimization, encompassing proactive planning and reactive adjustments to unforeseen disruptions. This paper addresses the complex job shop environment characterized by parallel machines within groups, shared machines across processes, and the occasional dedication of machine groups to specific processes due to extended processing times. We propose a novel realtime rescheduling methodology to enhance production efficiency in this dynamic setting. Our approach integrates a Genetic Algorithm (GA) with Adaptive Large Neighborhood Search (ALNS) to effectively explore a vast solution space. We further introduce batch splitting to increase flexibility and responsiveness to disruptions. Rigorous evaluation of diverse problem instances demonstrates the methodology's ability to minimize tardiness and makespan while maintaining computational efficiency. Significantly, our approach effectively repairs schedules disrupted by machine breakdowns, improving delivery times and reducing production costs.