cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17632/myggxy4mmw
title: TOP1 inhibition therapy protects against SARS-CoV-2-induced lethal inflammation. Ho et al.

description: Hyperinflammation that occurs during COVID19 is linked to increased disease severity and mortality. Reducing the magnitude of the inflammatory response during infection with SARS-CoV-2 might be key to the development of novel therapeutics against COVID19. We had previously shown that inhibition of epigenetic regulators such as Top1 can block lethal hyperinflammation associated with other models of bacterial and viral infections and co-infections. We first performed epigenetic characterization (Hi-C [table S1], H3K27ac ChIP Seq [table s2]) on A549-ACE2 cells infected with SARS-CoV-2 and identified a chromatin signature that is associated with SARS-CoV-2 infection. To then understand if Top1 is required for the inflammatory response against SARS-CoV-2, we performed RNA-sequencing in cells treated with control or TOP1 targeting siRNAs [table s3]. We found that genes associated with the inflammatory response are downregulated with TOP1 knockdown, suggesting that TOP1 is required for activating the inflammatory response in infected cells. Finally, we performed RNA-seq on the lungs of SARS-CoV-2 infected golden syrian hamsters that were treated either with DMSO vehicle control or topotecan (TPT), a TOP1 inhibitors [table s4]. We found that genes associated with the inflammatory response were down regulated in TPT treated hamsters. Histology scoring of the lungs of hamsters treated with TPT [table s5] also showed that these lungs were less inflammed. Taken together, our data suggest that TOP1 inhibition may be a suitable way to reduce inflammation in the context of SARS-CoV-2 infection.
DOI: 10.17632/nvrdxn35tb
title: Multiplexed LNP-mRNA vaccination against pathogenic coronavirus species. Peng et al

description: Original data of flow cytometry to check the characterization of  mRNA-LNP particles
DOI: 10.17632/p2xv7wsf28
title: Data for: Modified non-flat splash function in sand saltation

description: Original figure data
DOI: 10.17632/pbspmrj3hx
title: Entrevistas Proyecto Rehabilitación de la Visión

description: Transcripciones de entrevistas de proyecto cuyo objetivo fue: Describir las condiciones del acceso a la rehabilitación de la visión en Bucaramanga y su Área Metropolitana. Materiales y Métodos: Se realizó un estudio de caso colectivo tomando elementos de la fenomenología.  Se asumió la postura teórica de Andersen y colaboradores. Se realizaron entrevistas semi-estructuradas a 11 pacientes y profesionales involucrados en la atención y rehabilitación, residentes en municipios del área metropolitana de Bucaramanga. El análisis se hizo en tres momentos: descubrimiento, codificación e interpretación de los datos.  Se acudió al uso de técnicas de recolección de información que permitieran la conversación y el intercambio de experiencias entre los sujetos y las investigadoras, en este sentido se realizaron entrevistas semi-estructuradas las cuales permitieron captar vivencias, opiniones y concepciones sobre el acceso a los servicios de rehabilitación, así como los elementos críticos, que, de acuerdo con la trayectoria de cada persona, pueden estar afectando significativamente el acceso real a los servicios en las ciudades de estudio. 
Teniendo en cuenta las condiciones sanitarias por el brote de la COVID-19 y en algunos casos por las ocupaciones personales y profesionales que no hicieron posible el encuentro presencial, se realizaron entrevistas semiestructuradas telefónicas, las cuales fueron grabadas en medio digital, mediante el uso de una aplicación para tal fin. Una vez realizadas se guardaron e identificaron teniendo en cuenta la ciudad y el rol del entrevistado asignándose un número a cada una; posteriormente se transcribieron en su totalidad. Para el análisis de la información, se utilizó el análisis cualitativo propuesto por Taylor, siguiendo el momento de descubrimiento, codificación y relativización o interpretación de los datos. Se implementó la estrategia de triangulación de investigadoras, pues cada una codificó de forma independiente las transcripciones; los códigos y categorías resultantes se refinaron a través de reuniones de equipo en curso para participar en la reflexión colectiva, ampliando las posibilidades de codificación. Para apoyar el análisis se utilizó el software atlas.ti (v. 6.2). Todas las personas invitadas aceptaron participar y luego se solicitó su consentimiento informado verbal. En todo momento se garantizó el manejo ético, anónimo y confidencial de la información y del nombre de los participantes.  

Dos categorías emergen del estudio:  1. Rehabilitación de la visión: Un asunto incipiente. 2. Experiencia de las personas con baja visión frente a los procesos de atención para el manejo de la baja visión, con sus subcategorías: Fallas en la identificación y orientación frente al manejo de la baja visión y Dificultades para asistir a las atenciones clínicas y acceso a dispositivos opticos y no.   

En los cuatro municipios del estudio las personas experimentan múltiples barreras para lograr su rehabilitación de la vision.
DOI: 10.17632/ry2x2rgydz
title: Allergenic Protein Prediction Outputs of 4 Edible Insect Species 

description: Protein Information for silk moth (Bombyx mori), yellow mealworm (Tenebrio molitor), migratory locust (Locusta migratoria), and house cricket (Acheta domesticus) obtained from AllerCatPro 2.0, as well as tropomyosin sequences obtained from the 4 edible insects
DOI: 10.17632/s8h4n3khzp
title: Are Syrian children integrated into our education?: Turkish teacher perspectives on the inclusive education project

description: Transcripts of Interview data
DOI: 10.17632/v9njsfs4n2
title: Defense inducers mediated alleviation of biotic stress in tomato through alteration in oxidative stress markers (Dataset)

description: The research set out to determine the effect of the prophylactic and curative spray of the synthetic defense inducers on the tomato plant infected with Clavibacter michiganensis subsp michiganensis (Cmm), done at the Department of Plant Pathology, G B Pant University of Agriculture and Technology, India. In doing so, the tomato plants were artificially inoculated with Cmm, in two sets of plants receiving the treatment of SA, INA, BTH and lysozyme at the concentration of 200µM, 500µM and 800µM along with the positive and negative control, wherein one set of plants were treated before the pathogen inoculation and other was treated after the pathogen inoculation. The effect of defense inducers on plant was assessed through the enzymatic activity of PO (fig1), phenyl propanoid synthesis (Fig.2 and 3), PPO ( Fig.4), β-1,3 glucanase(PR2, Fig.5), hydrogen peroxide production in leaf tissues (Fig.6) and lignin deposition in stem section (Fig.7). In comparing all the treatments it was observed that the prophylactic treatment is more efficient than the curative treatment (Table1) in imparting resistance to the tomato plants against the invading pathogen. These Figures and Tables are present in the attached file titled "Mendely dataset for All Life Journal.docx".
DOI: 10.17632/vp27db45nm
title: FAVORABILIDAD GEOTÉRMICA APLICANDO EL MÉTODO DE ANÀLISIS GEOTHERMAL PLAY FAIRWAY  ÁREA 2, Sierras Subandinas, Cuenca de Tucumán y su extensión en la provincia de Santiago del Estero, Argentina

description: Geospatial data provided in shapefile and GeoTiff formats.
DOI: 10.17632/y4kgjrp6db
title: Data for: Ecotoxicity of oil sludges and residuals from their washing with surfactants: Soil dehydrogenase and ryegrass germination tests

description: The data presented here correspond to our manuscript: "Ecotoxicity of oil sludges and residuals from their washing with surfactants: Soil dehydrogenase and ryegrass germination tests". The files are labelled according to the toxicity test, "dha" for dehydrogenase activity test and "germination" for seed germination test. The datasheets have all the data with the replicates of all the experiments performed in our study.
DOI: 10.17632/zrt94j9kh4
title: JMTP hedonic communal

description: The data describes a scenario where wage theft is alleged to have taken place in a restaurant setting. There are 2 brands in the study; one, a fine dining restaurant, and second a casual chain. The main hypotheses is that the fine ding restaurant has lower brand credibility, integrity and attitude after reports of wage theft than the casual dining chain
DOI: 10.17632/2y29tsw7nh
title: Sampling and evaluation of basaltic rocks of the Faroe Islands: Details on material used in geochronological 40Ar/39Ar dating of local rocks

description: The analytical data presented in this ‘Supplement B' are linked to the geochronological study: “On the timing and nature of magmatism in the North Atlantic Igneous Province: New implications from basaltic rocks of the Faroe Islands” by Jógvan Hansen and Morgan Ganerød, 2023.
In the actual work new absolute/radiometric ages for onshore sill intrusions and selected lava flows cropping out in the Faroe Islands, by means of the K-Ar based 40Ar/39Ar incremental heating method, have been determined. The actual sills most likely reflect the final stages of magmatism in the Faroe Iceland Basalt Group (FIBG) subsequent to greater magmatic activity, linked to the onset of seafloor-spreading within this part of the NE Atlantic area at ~55.5 to ~56 Ma.
In this dataset contribution we provide info regarding collection of suitable rock samples, the nature of their petrography and finally, an overview is presented when it comes to major element compositions of individual samples.
DOI: 10.17632/6bknwxdbjg
title: Thermal structure beneath the Mt. Changbai Volcanic Area, northeastern Asia: New insights from temperature logging and numerical modeling

description: 1. Temperature logs
The well temperature was measured by a cable system consisting of a thermistor (max. temperature 350 °C) and a 5000-m cable. This system is manufactured by Pioneer Petrotech Services, Canada, and allows the temperature to be continuously recorded with a sensitivity of 0.01 C, a limiting accuracy of 0.1 C and a depth interval of 0.05 m. The four wells had sufficiently long shut-in times (the time elapsed after the cessation of drilling) for the temperature to recover. Well C-1, approximately 7 km north of the caldera center, is almost within the Tianchi caldera, whereas the other three wells are approximately 20 km to 60 km from the caldera. The measured data are listed in Dataset s1-s4.
2. Thermophysical parameters 
We measured the thermal conductivities and concentrations of heat-producing elements (Th, U, and K) in 19 core samples (from wells C-2 and C-3) and 12 outcrop samples (near wells C-1 and C-4) extracted from the representative lithologies of the four wells. The measured data are listed in Dataset s5.

Dataset S1. The temperature logs of C-1. 
Dataset S2. The temperature logs of C-2. 
Dataset S3. The temperature logs of C-3. 
Dataset S4. The temperature logs of C-4. 
Dataset S5. The measured thermal conductivity, U-Th-K concentration and heat production.
DOI: 10.17632/9y4ftbv2vz
title: Data of "Galectin-1 deletion in mice causes bone loss via impaired osteogenic differentiation potential of BMSCs"

description: Data of "Galectin-1 deletion in mice causes bone loss via impaired osteogenic differentiation potential of BMSCs"
DOI: 10.17632/mpmpx9wvfz
title: Study_HighMathAchievement

description: Data for the study titled: The Mathematical, Motivational, and Cognitive Characteristics of High Mathematics Achievers in Primary School
DOI: 10.17632/rsrkwvtp22
title: LINF_330015600

description: 2,4-dienoyl-CoA reductase
Leishmania infantum (strain JPCM5)
DOI: 10.17632/sybfrkt9gf
title: MD-HIT

description: MD-HIT code for controlling redundancy of materials datasets using either composition or structure features.
DOI: 10.17632/xnxkybct29
title: Data for: Fate of intertidal microphytobenthos nitrogen under enhanced nutrient availability: Evidence for a shift in the pool of retained nitrogen revealed through 15N-labeling

description: Data supporting a pulse-chase study of labeled 15N (ammonium) into sandy intertidal sediment that then underwent nutrient enrichment. The goal was to see how nutrient enrichment affected the fate and processing of the labeled N taken up by MPB.
DOI: 10.17632/674vgm3jtx
title: imported_fruits

description: imported fruits - Vietnam
DOI: 10.17632/cr9jf45xrr
title: Context embeddings trained on short sequence FASTA files with binding site

description: Data to generate "FIGURE 4: Context embeddings trained on short sequence FASTA files with binding site – N = 28,052" for "Vector Embeddings by Sequence Similarity and Context for Improved Compression, Similarity Search, Clustering, Organization, and Manipulation of cDNA Libraries" by Daniel H. Um, et al.
DOI: 10.17632/jn5ckdgsz6
title: Stimulating β-adrenergic receptors promotes synaptic potentiation by switching CaMKII movement from LTD to LTP mode

description: Learning, memory and cognition are thought to require synaptic plasticity, specifically including as hippocampal long-term potentiation and depression (LTP and LTD). LTP versus LTD is induced by high- versus low-frequency stimulation (HFS versus LFS) but, stimulating β-adrenergic receptors (βARs) enables LTP induction also by LFS (1 Hz) or theta frequencies (~5 Hz) that don’t cause plasticity by themselves. In contrast to HFS-LTP, such βAR-LTP requires Ca2+-flux through L-type voltage-gated Ca2+-channels, not NMDA-type glutamate receptors (NMDARs). Surprisingly, we found that βAR-LTP still required a non-ionotropic scaffolding function of the NMDAR: the stimulus-induced binding of the Ca2+/calmodulin-dependent protein kinase II (CaMKII) to its GluN2B subunit that mediates CaMKII movement to excitatory synapses. In hippocampal neurons, β-adrenergic stimulation with isoproterenol transformed LTD-type CaMKII movement to LTP-type movement, resulting in CaMKII movement to excitatory instead of inhibitory synapses. Additionally, isoproterenol enabled induction of a major cell-biological feature of LTP in response to LTD stimuli: increased SEP-GluA1 surface expression. Like for βAR-LTP in hippocampal slices, the isoproterenol effects on CaMKII movement and SEP-GluA1 surface expression involved L-type Ca2+-channels and specifically required β2-ARs. Taken together, these results indicate that isoproterenol transforms LTD stimuli to LTP signals by switching CaMKII movement and GluN2B binding to LTP mode.
DOI: 10.17632/jvnv64b34m
title: LINF_260013200

description: asparagine synthetase A
Leishmania infantum (strain JPCM5)
DOI: 10.17632/nnppdc3ryj
title: Numerical investigation of streamwise vortex-induced vibration at low Reynolds numbers: mass ratio effects

description: In this numerical study vortex-induced vibration of a circular cylinder is analyzed using an in-house code. Mass ratio values of m* = 2,5 and 10 are investigated at Reynolds number Re = 100. A single excitation region is observed in this study that corresponds to the second excitation branch found at moderately high-Re experiments. For a system without external damping the magnitude of the streamwise fluid force was found to be zero where the vibration frequency passes through the natural frequency in vacuum. At the same point the phase angle between displacement and streamwise fluid force shows changes.
DOI: 10.17632/shv6wk5mzs
title: SLC-2014-Yards

description: Salt Lake City study on yard biodiversity and homeowner preferences. Code published on github https://github.com/allieblanchette/SLC-2014-Yards
DOI: 10.17632/tf9j4xymj2
title: Heat transfer data of supercritical carbon dioxide flowing upwards in tubes

description: The data is uploaded to study heat transfer characteristics of SCO2 vertically flowing in a tube. The experiments were conducted by CNNC Key Laboratory Nuclear Reactor Thermal Hydraulics Technology, Nuclear Power Institute of China. More information can be found in the uploaded file.
DOI: 10.17632/275d8w3x3j
title: ANTAGONISM BETWEEN CO-INFECTING GASTROINTESTINAL NEMATODES: A META-ANALYSIS OF EXPERIMENTAL INFECTIONS IN SHEEP

description: Gastrointestinal nematodes (GIN) have enormous global impacts in humans, wildlife and grazing livestock. Within grazing livestock, sheep are of particular global importance and the economics and sustainability of sheep production are greatly constrained by GIN infections. Natural infections are composed of co-infections with multiple species, and while some past work suggests species can interact negatively with one another within the same host, there is wide variation in reported patterns. Here, we undertook a systematic literature search and meta-analysis of experimental GIN co-infections of sheep to determine whether these experimental studies support the hypothesis of antagonistic interactions between different co-infecting GIN, and test whether aspects of parasite biology or experimental design influence the observed effects. 
A systematic search of the literature yielded 4848 studies, within which, we identified 19 experimental sheep studies comparing post-mortem worm counts across two co-infecting GIN species. Meta-analysis of 67 effects obtained from these studies provides strong evidence for interactions between GIN species. There was wide variation in the strength and direction of these interactions, but the global effect was significantly antagonistic. On average, there was a decrease in the number of worms of one species when a co-infecting species was also present, relative to a mono-infection with that species alone. This effect was dependent on the infectious dose and was rapidly lost after anthelmintic treatment, suggesting that live worms are required for the effect to occur. Individual parasite species varied in the extent to which they both exerted, and were subject to, these interspecies interactions, and these differences are more complex than simply co-localisation within the gastrointestinal tract.
Antagonistic interactions between co-infecting GIN may feedback into their epidemiology as well as potentially affecting the clinical impacts of infection. Furthermore, the consequences of these interactions may be heightened when clinical interventions affect only one species within the co-infecting network. Whilst it was not possible to identify the causes of variation between GIN species in the impact of co-infection, these findings point to new avenues for epidemiological, clinical and mechanistic research on GIN co-infections.
DOI: 10.17632/3cbsvgdzvb
title: LINF_310038600

description: protein of unknown function - conserved; Leishmania infantum (strain JPCM5)
DOI: 10.17632/7k28x8tys6
title: Boivin_et_al_Nanaimo Depth Profiling Table of Isotopic Data

description: Table 1 contains acquisition parameters. 
Table 2 contains isotopic data for detrital zircon grains from the Nanaimo Group. This table is divided into three columns. The first column is for homogenous grains. The second and third columns are rim and core measurements for heterogeneous grains. The results of measurements of validation reference materials is included above the data from each measurement session.
DOI: 10.17632/7km9wcspn3
title: Portable CPU implementation of Wilson, Brillouin and Susskind fermions in lattice QCD

description: A modern Fortran implementation of three Dirac operators (Wilson, Brillouin, Susskind) in lattice QCD is presented, based on OpenMP shared-memory parallelization and SIMD pragmas. The main idea is to apply a Dirac operator to N_v vectors simultaneously, to ease the memory bandwidth bottleneck. All index computations are left to the compiler and maximum weight is given to portability and flexibility. The lattice volume, N_x N_y n_z N_t, the number of colors, N_c, and the number of right-hand sides, N_v, are parameters defined at compile time. Several memory layout options are compared. The code performs well on modern many-core architectures (480 Gflop/s, 880 Gflop/s, and 780 Gflop/s with N_v = 12 for the three operators in single precision on a 72-core KNL processor, a 2 x 24-core Skylake node yields similar results). Explicit run-time tests with CG/BiCGstab inverters confirm that the memory layout is relevant for the KNL, but less so for the Skylake architecture. The ancillary code distribution contains all routines, including the single, double, and mixed precision Krylov space solvers, to render it self-contained and ready-to-use.
DOI: 10.17632/f44gwcnvbv
title: Dados - Perfil dos vacinadores brasileiros

description: Base de dados sobre o perfil dos vacinadores brasileiros
DOI: 10.17632/h8wbcjkc5j
title: LINF_180022300

description: gamma-glutamylcysteine synthetase | GSH1
Leishmania infantum (strain JPCM5)
DOI: 10.17632/kszs274kf5
title: Data for: Analysis of the cloud-to-ground lightning characteristics before and after installation of the coastal and inland wind farms in China

description: Analysis results of the cloud to ground lightning activities over the wind farms in China
DOI: 10.17632/nfxbn5jf2h
title: Wagner's Law

description: Data on per capita GDP and state expenditures of 12 Indian states.
DOI: 10.17632/rz8px48ysr
title: PSME3 alleviates the onset of PE via mediating the ubiquitin-independent degradation of UBE2V2

description: Raw data of protein expression levels in TMT quantitative mass spectrometry, with the control group being shNC (shNC1, shNC2, shNC3) and the experimental group being shPSME3.
DOI: 10.17632/sdkgv34spb
title: Dataset: The psychometric properties of the 360° Servant Leadership Competency Appraisal [360° SLCA]: A servant leadership competence measure

description: Dataset of managers and employees that completed the 360 Servant Leader Competency Appraisal.
DOI: 10.17632/xb4r9vbh7x
title: Experimental data - Fitness effects of a demography-dispersal trade-off in expanding Saccharomyces cerevisiae mats - Physical Biology 2023

description: Data for experimental results obtained from TBR1 and TBR5 yeast mat experiments. Data that was used to generate the figures are included in excel sheets in the corresponding folder for each figure. Each figure can be generated by running the m file (in MATLAB) while having all the data files (corresponding to each figure) downloaded into the same folder.
DOI: 10.17632/zjfpsfd95k
title: From crystal phase mixture to pure metal-organic frameworks – Tuning pore and structure properties

description: The deposit contains data for the paper "From crystal phase mixture to pure metal-organic frameworks – Tuning pore and structure properties" including BET, CIF files, cRED, FTIR, Raman, QEXAFSm SXRD, XRD, SEM, TEM.