cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.6127043.v1
title: Leadless Pacing: Current State and Future Direction

description: <b>Article full text</b> <br> The full text of this article can be found here<b>. </b>https://link.springer.com/article/10.1007/s40119-017-0097-3 <br> <b>Provide enhanced content for this article</b> <br> If you are an author of this publication and would like to provide additional enhanced content for your article then please contact <b>adisrapidplus@springer.com</b>. <br> The journal offers a range of additional features designed to increase visibility and readership. All features will be thoroughly peer reviewed to ensure the content is of the highest scientific standard and all features are marked as ‘peer reviewed’ to ensure readers are aware that the content has been reviewed to the same level as the articles they are being presented alongside. Moreover, all sponsorship and disclosure information is included to provide complete transparency and adherence to good publication practices. This ensures that however the content is reached the reader has a full understanding of its origin. No fees are charged for hosting additional open access content. <br> Other enhanced features include, but are not limited to: <br> • Slide decks • Videos and animations • Audio abstracts • Audio slides
DOI: 10.6084/m9.figshare.6126989
title: Data tables. The mafic alkaline volcanism of SW Madagascar (Ankililoaka, Tulear region): <sup>40</sup>Ar/<sup>39</sup>Ar ages, geochemistry and tectonic setting

description: X-ray fluorescence whole-rock data, mineral compositions, <sup>40</sup>Ar/<sup>39</sup>Ar dataset, mantle source modelling and figures showing volcanological features and thin sections.
DOI: 10.6084/m9.figshare.6126989.v1
title: Data tables. The mafic alkaline volcanism of SW Madagascar (Ankililoaka, Tulear region): <sup>40</sup>Ar/<sup>39</sup>Ar ages, geochemistry and tectonic setting

description: X-ray fluorescence whole-rock data, mineral compositions, <sup>40</sup>Ar/<sup>39</sup>Ar dataset, mantle source modelling and figures showing volcanological features and thin sections.
DOI: 10.6084/m9.figshare.6126974
title: Sill Dimensions data collection.xlsx

description: This is a spreadsheet of measurements on igneous sills intruding sedimentary basins, imaged on seismic reflection data. The measurements were made from a variety of commercial and non-commercial seismic surveys. The data is naturally full of gaps due to different data types and measurements made on each survey. The spreadsheet has a second tab of data that has been cleaned for download and analysis.
DOI: 10.6084/m9.figshare.6126974.v1
title: Sill Dimensions data collection.xlsx

description: This is a spreadsheet of measurements on igneous sills intruding sedimentary basins, imaged on seismic reflection data. The measurements were made from a variety of commercial and non-commercial seismic surveys. The data is naturally full of gaps due to different data types and measurements made on each survey. The spreadsheet has a second tab of data that has been cleaned for download and analysis.
DOI: 10.6084/m9.figshare.6126959
title: Supplementary Material for: Integrative Bioinformatics Analysis Provides Insight into the Molecular Mechanisms of Chronic Kidney Disease

description: <b><i>Background/Aims:</i></b> Chronic kidney disease (CKD) is a worldwide public health problem. Regardless of the underlying primary disease, CKD tends to progress to end-stage kidney disease, resulting in unsatisfactory and costly treatment. Its common pathogenesis, however, remains unclear. The aim of this study was to provide an unbiased catalog of common gene-expression changes of CKD and reveal the underlying molecular mechanism using an integrative bioinformatics approach. <b><i>Methods:</i></b> We systematically collected over 250 Affymetrix microarray datasets from the glomerular and tubulointerstitial compartments of healthy renal tissues and those with various types of established CKD (diabetic kidney disease, hypertensive nephropathy, and glomerular nephropathy). Then, using stringent bioinformatics analysis, shared differentially expressed genes (DEGs) of CKD were obtained. These shared DEGs were further analyzed by the gene ontology (GO) and pathway enrichment analysis. Finally, the protein-protein interaction networks(PINs) were constructed to further refine our results. <b><i>Results:</i></b> Our analysis identified 176 and 50 shared DEGs in diseased glomeruli and tubules, respectively, including many transcripts that have not been previously reported to be involved in kidney disease. Enrichment analysis also showed that the glomerular and tubulointerstitial compartments underwent a wide range of unique pathological changes during chronic injury. As revealed by the GO enrichment analysis, shared DEGs in glomeruli were significantly enriched in exosomes. By constructing PINs, we identified several hub genes (e.g. OAS1, JUN, and FOS) and clusters that might play key roles in regulating the development of CKD. <b><i>Conclusion:</i></b> Our study not only further reveals the unifying molecular mechanism of CKD pathogenesis but also provides a valuable resource of potential biomarkers and therapeutic targets.
DOI: 10.6084/m9.figshare.6126947
title: Genetic diversity statistics by gene.

description: Genetic diversity statistics by gene, including ncRNAs. From 57 non-clonal strains.
DOI: 10.6084/m9.figshare.6126947.v2
title: Genetic diversity statistics by gene.

description: Genetic diversity statistics by gene, including ncRNAs. From 57 non-clonal strains.
DOI: 10.6084/m9.figshare.6126947.v1
title: Genetic diversity statistics by gene.

description: Genetic diversity statistics by gene, including ncRNAs. From 57 non-clonal strains.
DOI: 10.6084/m9.figshare.6126932
title: Supplementary Material for: Survival of Hepatocellular Carcinoma Patients Treated with Sorafenib beyond Progression

description: <b><i>Background/Aim:</i></b> Sorafenib leads to improved survival in advanced hepatocellular carcinoma (HCC) patients. Continuation of sorafenib beyond progression has been a possible treatment strategy when further approved therapeutic agents are lacking. <b><i>Methods:</i></b> We performed a retrospective analysis of all HCC patients at our institution with documented disease progression under treatment with sorafenib. Overall survival (OS) from start of sorafenib treatment was compared between patients who received sorafenib for &gt; 3 weeks beyond progression (group 1) and those who discontinued sorafenib ≤3 weeks after progression (group 2). Group 1 was further subdivided into those patients who received sorafenib for &gt; 3 months (group 1a) and those who received it for ≤3 months (group 1b). <b><i>Results:</i></b> A total of 71 patients were analyzed. Median OS for all patients was 15.4 months. OS in group 1 (15.6 months) and 2 (13.0 months) was similar (<i>p</i> = 0.90). Patients in group 1a showed significantly prolonged median OS (19.7 months) compared to that of patients in group 1b (13.6 months, <i>p</i> = 0.004), and they showed a trend towards prolonged OS compared to group 2 (<i>p</i> = 0.126). For patients with a poor prognosis according to their Child-Pugh stage, performance status, alpha-fetoprotein, and response to prior sorafenib treatment, OS was significantly prolonged in group 1 versus group 2 (12.1 vs. 6.4 months, <i>p</i> = 0.019). <b><i>Conclusion:</i></b> In HCC patients, continuing sorafenib beyond progression for &gt; 3 months is associated with improved survival compared to discontinuing sorafenib within 3 months. Furthermore, patients with a poor prognosis who continue sorafenib beyond progression in general show significantly prolonged survival.
DOI: 10.6084/m9.figshare.6126932.v1
title: Supplementary Material for: Survival of Hepatocellular Carcinoma Patients Treated with Sorafenib beyond Progression

description: <b><i>Background/Aim:</i></b> Sorafenib leads to improved survival in advanced hepatocellular carcinoma (HCC) patients. Continuation of sorafenib beyond progression has been a possible treatment strategy when further approved therapeutic agents are lacking. <b><i>Methods:</i></b> We performed a retrospective analysis of all HCC patients at our institution with documented disease progression under treatment with sorafenib. Overall survival (OS) from start of sorafenib treatment was compared between patients who received sorafenib for &gt; 3 weeks beyond progression (group 1) and those who discontinued sorafenib ≤3 weeks after progression (group 2). Group 1 was further subdivided into those patients who received sorafenib for &gt; 3 months (group 1a) and those who received it for ≤3 months (group 1b). <b><i>Results:</i></b> A total of 71 patients were analyzed. Median OS for all patients was 15.4 months. OS in group 1 (15.6 months) and 2 (13.0 months) was similar (<i>p</i> = 0.90). Patients in group 1a showed significantly prolonged median OS (19.7 months) compared to that of patients in group 1b (13.6 months, <i>p</i> = 0.004), and they showed a trend towards prolonged OS compared to group 2 (<i>p</i> = 0.126). For patients with a poor prognosis according to their Child-Pugh stage, performance status, alpha-fetoprotein, and response to prior sorafenib treatment, OS was significantly prolonged in group 1 versus group 2 (12.1 vs. 6.4 months, <i>p</i> = 0.019). <b><i>Conclusion:</i></b> In HCC patients, continuing sorafenib beyond progression for &gt; 3 months is associated with improved survival compared to discontinuing sorafenib within 3 months. Furthermore, patients with a poor prognosis who continue sorafenib beyond progression in general show significantly prolonged survival.
DOI: 10.6084/m9.figshare.6126911
title: Horizontal subzone characteristics and methane seepage properties of the gas flowing fracture zone above the gob

description: In this paper, based on the development height of a GFFZ above the gob, the GFFZ was horizontally divided into the following: a lateral fracture subzone, an O-ring fracture subzone, and a compacted subzone. The identification criteria for all of these horizontal subzones were given by analyzing the influence of the stress in the coal rock mass on the development of mining-induced fractures. A numerical simulation study was conducted for the influences of the mining height and mining depth on the morphological development of all horizontal subzones of the GFFZ, and the simulation results showed that the mining height was the main factor influencing the development characteristics of horizontal subzones of the GFFZ. Both the maximum distance of the lateral fracture subzone beyond the mining boundary and the width of the O-ring fracture subzone increased with the increase of mining height. A physical simulation experiment was performed for extraction of gob methane through a surface borehole, and the experimental results showed that the gas flow state was laminar within the range of the lateral fracture subzone and the compacted subzone but that the gas flow state was turbulent, not following Darcy's law, within the range of the O-ring fracture subzone
DOI: 10.6084/m9.figshare.6126866
title: Pre-computed Functional Brain Networks for Healthy Controls

description: - the Correlation of Envelope - iPLV- PLV
DOI: 10.6084/m9.figshare.6126863
title: Supplementary Material for: Effect of Transversus Abdominis Plane Block on Postoperative Pain after Colorectal Surgery: A Meta-Analysis of Randomized Controlled Trials

description: <b><i>Objectives:</i></b> To assess the analgesic efficacy of transversus abdominis plane (TAP) block in patients undergoing colorectal surgery (CRS). <b><i>Materials and Methods:</i></b> The databases of PubMed, ISI Web of Science, and Embase were searched, and randomized controlled studies (RCTs) that compared TAP block to control for relief of postoperative pain in patients who underwent CRS were included. Outcomes, including postoperative pain at rest and with movement, morphine use, postoperative nausea and vomiting, and the length of hospital stay, were analyzed using STATA software. The weighted mean differences (WMDs) with 95% confidence intervals (95% CIs) or relative risk with 95% CI were used to present the strength of associations. <b><i>Results:</i></b> A total of 7 RCTs with 511 patients were included. The results of this study suggested that TAP block significantly relieved postoperative pain during postanesthetic recovery after CRS at rest and during movement (WMDs were –0.98 [95% CI –1.57 to –0.38] and –0.68 [–1.07 to –0.30], respectively), and also decreased pain intensity during movement 24 h after CRS (WMD: –0.57 [95% CI –1.06 to –0.08]). TAP block significantly reduced opioid consumption within 24 h when compared to controls, with a WMD of 15.66 (95% CI –23.93 to –7.39). However, TAP block did not shorten the length of hospital stay. <b><i>Conclusions:</i></b> TAP block was an effective approach for relief of postoperative pain and reduced postoperative consumption of morphine. More RCTs with large sample sizes are required to confirm these findings.
DOI: 10.6084/m9.figshare.6126854
title: Supplementary Material for: In utero Fetal Intubation for a Large Neck Mass: A Minimally Invasive EXIT Option

description: Fetuses with obstructive neck and orofacial lesions have been delivered via an ex utero intrapartum treatment (EXIT) procedure to facilitate securement of the airway while on placental circulation. Pregnancy-related cardiovascular changes and technical issues unique to an EXIT procedure increase fetal and maternal risks relative to a standard cesarean section. In order to circumvent such issues, fetal endoscopic intubation has been proposed. We report a case of a fetus with a large neck mass (mixed solid and multiloculated cystic lesion measuring 9.2 × 5.3 × 8.5 cm, neck hyperextension, protruding tongue, and serial gagging movements) that was successfully intubated in utero<i></i> and delivered at 36 weeks and 0 days via standard cesarean section, thereby avoiding an EXIT procedure. The risks, benefits, and technical issues of in utero tracheal intubation are reviewed.
DOI: 10.6084/m9.figshare.6126854.v1
title: Supplementary Material for: In utero Fetal Intubation for a Large Neck Mass: A Minimally Invasive EXIT Option

description: Fetuses with obstructive neck and orofacial lesions have been delivered via an ex utero intrapartum treatment (EXIT) procedure to facilitate securement of the airway while on placental circulation. Pregnancy-related cardiovascular changes and technical issues unique to an EXIT procedure increase fetal and maternal risks relative to a standard cesarean section. In order to circumvent such issues, fetal endoscopic intubation has been proposed. We report a case of a fetus with a large neck mass (mixed solid and multiloculated cystic lesion measuring 9.2 × 5.3 × 8.5 cm, neck hyperextension, protruding tongue, and serial gagging movements) that was successfully intubated in utero<i></i> and delivered at 36 weeks and 0 days via standard cesarean section, thereby avoiding an EXIT procedure. The risks, benefits, and technical issues of in utero tracheal intubation are reviewed.
DOI: 10.6084/m9.figshare.6126776
title: Codes and Data - Lebreton et al. Science Advances 2018

description: This folder contains all codes and data necessary to reproduce the analyses and results reported in Lebreton, et al. (2018) Science Advances. <br><br>[M. Lebreton, S. Langdon, M. J. Slieker, J. S. Nooitgedacht, A. E. Goudriaan, D. Denys, R. J. van Holst and J. Luigjes (2018) Two sides of the same coin: monetary incentives concurrently improve and bias confidence judgments, Science Advances (https://doi.org/10.1126/sciadv.aaq0668) ]<br><br>Please note that the codes needs Matlab R2014b or a more resent version, with the Statistics and Machine Learning toolbox.<br><br>
DOI: 10.6084/m9.figshare.6126713
title: Supplementary Material for: Increased Group 2 Innate Lymphoid Cells Are Correlated with Eosinophilic Granulocytes in Patients with Allergic Airway Inflammation

description: The T helper 2 (Th2)-type response was considered the hypostasis of allergic airway diseases, including asthma and allergic rhinitis (AR). However, more recent studies have suggested that allergic airway inflammation also depends on innate immunity and is closely related to group 2 innate lymphoid cells (ILC2s). This study evaluated the ILC2 levels of asthma subjects, patients with asthma and AR, and healthy individuals, regarding how to investigate the relationship between clinical data and ILC2 levels. It was found that asthma patients and asthma with AR patients had higher ILC2 levels compared to healthy subjects. ILC2s were positively correlated with the percentage of eosinophils in patients with asthma and AR, but not with pulmonary function. ILC2 levels were higher in mild asthma subjects than in patients with severe asthma. This study provides a new interpretation of the pathogenesis of allergic airway inflammation and may provide a new direction for the diagnosis and assessment of allergic airway diseases.
DOI: 10.6084/m9.figshare.6126713.v1
title: Supplementary Material for: Increased Group 2 Innate Lymphoid Cells Are Correlated with Eosinophilic Granulocytes in Patients with Allergic Airway Inflammation

description: The T helper 2 (Th2)-type response was considered the hypostasis of allergic airway diseases, including asthma and allergic rhinitis (AR). However, more recent studies have suggested that allergic airway inflammation also depends on innate immunity and is closely related to group 2 innate lymphoid cells (ILC2s). This study evaluated the ILC2 levels of asthma subjects, patients with asthma and AR, and healthy individuals, regarding how to investigate the relationship between clinical data and ILC2 levels. It was found that asthma patients and asthma with AR patients had higher ILC2 levels compared to healthy subjects. ILC2s were positively correlated with the percentage of eosinophils in patients with asthma and AR, but not with pulmonary function. ILC2 levels were higher in mild asthma subjects than in patients with severe asthma. This study provides a new interpretation of the pathogenesis of allergic airway inflammation and may provide a new direction for the diagnosis and assessment of allergic airway diseases.
DOI: 10.6084/m9.figshare.6126641
title: Bird_nest_analysis_code

description: This is code and data used for the bird nest paper
DOI: 10.6084/m9.figshare.6126332
title: Additional file 7: of Genomic heritability estimates in sweet cherry reveal non-additive genetic variance is relevant for industry-prioritized traits

description: Breeding values, dominance values, epistatic values and genetic values of all individuals for all traits in the RosBREED sweet cherry Crop Reference Set. An online app for exploring the breeding and genetic values presented in Additional file 7 is available at:Â https://www.rosbreed.org/breeding/cherry/gebv . (XLSX 791 kb)
DOI: 10.6084/m9.figshare.6126332.v1
title: Additional file 7: of Genomic heritability estimates in sweet cherry reveal non-additive genetic variance is relevant for industry-prioritized traits

description: Breeding values, dominance values, epistatic values and genetic values of all individuals for all traits in the RosBREED sweet cherry Crop Reference Set. An online app for exploring the breeding and genetic values presented in Additional file 7 is available at:Â https://www.rosbreed.org/breeding/cherry/gebv . (XLSX 791 kb)
DOI: 10.6084/m9.figshare.6126326
title: Additional file 5: of Genomic heritability estimates in sweet cherry reveal non-additive genetic variance is relevant for industry-prioritized traits

description: Variance component percentages for all RosBREED sweet cherry traits. (CSV 3 kb)
DOI: 10.6084/m9.figshare.6126326.v1
title: Additional file 5: of Genomic heritability estimates in sweet cherry reveal non-additive genetic variance is relevant for industry-prioritized traits

description: Variance component percentages for all RosBREED sweet cherry traits. (CSV 3 kb)
DOI: 10.6084/m9.figshare.6126323
title: Additional file 4: of Genomic heritability estimates in sweet cherry reveal non-additive genetic variance is relevant for industry-prioritized traits

description: Variance component estimates and standard errors for all RosBREED sweet cherry traits. (CSV 5 kb)
DOI: 10.6084/m9.figshare.6126323.v1
title: Additional file 4: of Genomic heritability estimates in sweet cherry reveal non-additive genetic variance is relevant for industry-prioritized traits

description: Variance component estimates and standard errors for all RosBREED sweet cherry traits. (CSV 5 kb)
DOI: 10.6084/m9.figshare.6126317
title: Additional file 2: of Genomic heritability estimates in sweet cherry reveal non-additive genetic variance is relevant for industry-prioritized traits

description: Number of observations (N) and Spearman rank correlations (Ď ) between genetic values derived from a single year and the multi-year genetic values using the ADI model (Panel A) or the phenotypic data (Panel B), genetic values derived from the reduced models and the full model (Panel C), and breeding values derived from the reduced models and the full model (Panel D). (XLSX 11 kb)
DOI: 10.6084/m9.figshare.6126317.v1
title: Additional file 2: of Genomic heritability estimates in sweet cherry reveal non-additive genetic variance is relevant for industry-prioritized traits

description: Number of observations (N) and Spearman rank correlations (Ď ) between genetic values derived from a single year and the multi-year genetic values using the ADI model (Panel A) or the phenotypic data (Panel B), genetic values derived from the reduced models and the full model (Panel C), and breeding values derived from the reduced models and the full model (Panel D). (XLSX 11 kb)
DOI: 10.6084/m9.figshare.6126311
title: Additional file 1: of Genomic heritability estimates in sweet cherry reveal non-additive genetic variance is relevant for industry-prioritized traits

description: Individuals from the RosBREED sweet cherry Crop Reference set used in this study. “Self” refers to individuals derived from self-pollination, and “Unk” means that at least one parent is not known. (XLSX 17 kb)
DOI: 10.6084/m9.figshare.6126311.v1
title: Additional file 1: of Genomic heritability estimates in sweet cherry reveal non-additive genetic variance is relevant for industry-prioritized traits

description: Individuals from the RosBREED sweet cherry Crop Reference set used in this study. “Self” refers to individuals derived from self-pollination, and “Unk” means that at least one parent is not known. (XLSX 17 kb)
DOI: 10.6084/m9.figshare.6126287
title: Additional file 4: of l-carnitine in critically ill patients—a case series study

description: Figure S4. Correlation of BMI and SOFA score with the change in f-Carnitine from day 0 to day 14. (a) Each plot depicts a relationship between the BMI on the x-axis, and the change of f-Carnitine from day 0 to day 14 (Δ f-Carnitine) on the y-axis. There was a significant negative correlation between the BMI and the Δf-Carnitine (r = − 0.47, p = 0.01), which suggests an association between lower BMI and larger decrease of f-Carnitine. (b) Each plot depicts a relationship between the SOFA score at the time of ICU admission on the x-axis, and the change of f-Carnitine from day 0 to day 14 (Δ f-Carnitine) on the y-axis. There was a significant correlation between the SOFA score on ICU admission and the Δf-Carnitine (r = 0.46, p = 0.01), which suggests an association between high SOFA score and larger decrease of f-Carnitine. (ZIP 188 kb)