cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.30746651
title: Development of a novel alpha7-nicotinic acetylcholine receptor-selective cell-penetrating peptide for intracellular cargo transport

description: Cell membranes present barriers to the intracellular delivery of therapeutic agents. This impediment is frequently exacerbated by the hydrophobic characteristics of many such molecules, ultimately reducing the efficiency of their cellular uptake and therapeutic effectiveness. Therapeutics are being created that exploit natural bypass mechanisms by forming complexes with cell-penetrating peptides (CPPs) derived from viruses. However, current CPPs lack the ability to selectively target precise cellular macromolecules. As a result, they are distributed broadly and cause off-target side effects. Neurotropic CPPs derived from the rabies virus glycoprotein (RVG) can access the brain by binding to plasma membrane targets, including, but not exclusively, nicotinic acetylcholine receptors (nAChRs). To overcome this barrier of minimal target selectivity, we designed several chimeric peptides composed of regions from the RVG and <i>α</i>-bungarotoxin, an α7 subtype-selective protein. Using human nAChRs expressed in <i>Xenopus laevis</i> oocytes, we screened the selectivity of our peptides using two-electrode voltage clamp electrophysiology. We identified a peptide with improved α7 nAChR subtype selectivity and apparent potency compared to the control RVG peptide. Using mammalian Neuro-2a cells, we demonstrated that our peptide depends on α7 nAChR plasma membrane expression to internalize and carry small-molecule payloads into neuronal-like cells without significant cytotoxic effects. Our novel α7 nAChR subtype-selective CPP may be useful in research applications requiring cargo delivery. Translationally, our α7 nAChR-selective CPP holds potential to be a dual drug delivery system to transport cargo into the brain for the treatment of neurological diseases.
DOI: 10.6084/m9.figshare.30746651.v1
title: Development of a novel alpha7-nicotinic acetylcholine receptor-selective cell-penetrating peptide for intracellular cargo transport

description: Cell membranes present barriers to the intracellular delivery of therapeutic agents. This impediment is frequently exacerbated by the hydrophobic characteristics of many such molecules, ultimately reducing the efficiency of their cellular uptake and therapeutic effectiveness. Therapeutics are being created that exploit natural bypass mechanisms by forming complexes with cell-penetrating peptides (CPPs) derived from viruses. However, current CPPs lack the ability to selectively target precise cellular macromolecules. As a result, they are distributed broadly and cause off-target side effects. Neurotropic CPPs derived from the rabies virus glycoprotein (RVG) can access the brain by binding to plasma membrane targets, including, but not exclusively, nicotinic acetylcholine receptors (nAChRs). To overcome this barrier of minimal target selectivity, we designed several chimeric peptides composed of regions from the RVG and <i>α</i>-bungarotoxin, an α7 subtype-selective protein. Using human nAChRs expressed in <i>Xenopus laevis</i> oocytes, we screened the selectivity of our peptides using two-electrode voltage clamp electrophysiology. We identified a peptide with improved α7 nAChR subtype selectivity and apparent potency compared to the control RVG peptide. Using mammalian Neuro-2a cells, we demonstrated that our peptide depends on α7 nAChR plasma membrane expression to internalize and carry small-molecule payloads into neuronal-like cells without significant cytotoxic effects. Our novel α7 nAChR subtype-selective CPP may be useful in research applications requiring cargo delivery. Translationally, our α7 nAChR-selective CPP holds potential to be a dual drug delivery system to transport cargo into the brain for the treatment of neurological diseases.
DOI: 10.6084/m9.figshare.30746653
title: Kratom Beverages Online: Marketing Narratives, Content, Dosing, and Potential Risks

description: In the past five years, the market for pre-made kratom, or <i>Mitragyna speciosa</i>, drinks has expanded rapidly. They are now sold in retail stores, convenience stores, grocery stores, specialty tobacco shops, and online. Despite their rapid market expansion, significant gaps remain in our understanding of their online marketing strategies, reported kratom content, dosing information, and serving sizes. To examine the online marketing practices of pre-made kratom beverages sold in the United States, with a focus on transparency, dosage information, and public health risks. We analyzed the front labels and websites of 107 ready-to-drink kratom products using Python-based web scraping and manual image inspection. We examined marketed benefits, ingredient lists, dosage recommendations, and the presence of warnings or Food and Drug Administration (FDA) disclaimers. Kratom content ranged from 20 mg to 500 mg per drink and was reported using inconsistent terms such as “extract,” “alkaloids,” or “mitragynine.” Serving suggestions varied from one to fifteen servings per drink, and the recommended dose ranged from 17.5 mg to 350 mg. Marketing of the product most emphasized natural or organic qualities and wellness related claims. The considerable variation in reported kratom content, dose, and serving size, together with its frequent framings as a “health-based” product, points to a need for stronger regulation. Policies should include evidence-based dosing recommendations, standardized and transparent online descriptions and warnings, and clear marketing guidelines for kratom beverages promoted as natural or wellness products.
DOI: 10.6084/m9.figshare.30746653.v1
title: Kratom Beverages Online: Marketing Narratives, Content, Dosing, and Potential Risks

description: In the past five years, the market for pre-made kratom, or <i>Mitragyna speciosa</i>, drinks has expanded rapidly. They are now sold in retail stores, convenience stores, grocery stores, specialty tobacco shops, and online. Despite their rapid market expansion, significant gaps remain in our understanding of their online marketing strategies, reported kratom content, dosing information, and serving sizes. To examine the online marketing practices of pre-made kratom beverages sold in the United States, with a focus on transparency, dosage information, and public health risks. We analyzed the front labels and websites of 107 ready-to-drink kratom products using Python-based web scraping and manual image inspection. We examined marketed benefits, ingredient lists, dosage recommendations, and the presence of warnings or Food and Drug Administration (FDA) disclaimers. Kratom content ranged from 20 mg to 500 mg per drink and was reported using inconsistent terms such as “extract,” “alkaloids,” or “mitragynine.” Serving suggestions varied from one to fifteen servings per drink, and the recommended dose ranged from 17.5 mg to 350 mg. Marketing of the product most emphasized natural or organic qualities and wellness related claims. The considerable variation in reported kratom content, dose, and serving size, together with its frequent framings as a “health-based” product, points to a need for stronger regulation. Policies should include evidence-based dosing recommendations, standardized and transparent online descriptions and warnings, and clear marketing guidelines for kratom beverages promoted as natural or wellness products.
DOI: 10.6084/m9.figshare.30746654
title: Study on criticality uncertainties of MCCI products due to concrete compositions

description: The criticality properties of fuel debris from Molten Core-Concrete Interaction (MCCI) are considered to depend on the composition of the concrete aggregate. Various concrete aggregate compositions are known, and experiments have been conducted to produce MCCI using concretes with different aggregates, but few studies have addressed their criticality characteristics. From these backgrounds, critical experiments at the modified Static Experiment Critical Facility (STACY) were conducted to clarify the criticality characteristics of fuel debris by making structural simulant rods of mortar composition that did not contain aggregate to simulate concrete. In this study, to evaluate the representativeness of the samples used in the STACY experiment, we clarified differences in criticality characteristics, such as effective multiplication factors, under varying neutron moderation and moisture conditions for concretes with typical compositions and for the experimental mortar composition. In addition, the critical radius and the possible range of critical mass, which are important for handling fuel debris, were clarified. We also evaluated the impact on effective multiplication due to uncertainties in composition. As a result, it can be concluded that differences in criticality characteristics due to aggregate type, including compositional uncertainties, are generally small.
DOI: 10.6084/m9.figshare.30746654.v1
title: Study on criticality uncertainties of MCCI products due to concrete compositions

description: The criticality properties of fuel debris from Molten Core-Concrete Interaction (MCCI) are considered to depend on the composition of the concrete aggregate. Various concrete aggregate compositions are known, and experiments have been conducted to produce MCCI using concretes with different aggregates, but few studies have addressed their criticality characteristics. From these backgrounds, critical experiments at the modified Static Experiment Critical Facility (STACY) were conducted to clarify the criticality characteristics of fuel debris by making structural simulant rods of mortar composition that did not contain aggregate to simulate concrete. In this study, to evaluate the representativeness of the samples used in the STACY experiment, we clarified differences in criticality characteristics, such as effective multiplication factors, under varying neutron moderation and moisture conditions for concretes with typical compositions and for the experimental mortar composition. In addition, the critical radius and the possible range of critical mass, which are important for handling fuel debris, were clarified. We also evaluated the impact on effective multiplication due to uncertainties in composition. As a result, it can be concluded that differences in criticality characteristics due to aggregate type, including compositional uncertainties, are generally small.
DOI: 10.15468/dl.pty9su
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Cleaveius puriensis",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017638-251120083545085/datasets/export for details.
DOI: 10.15468/dl.3ze77n
title: Occurrence Download

description: A dataset containing 41050 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Lolium rigidum",
 "HasCoordinate is true"
 ]
}

 The dataset includes 41050 records from 486 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017639-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.am7mtw
title: Occurrence Download

description: A dataset containing 97 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Breviceps sylvestris FitzSimons, 1930"
 ]
}

 The dataset includes 97 records from 9 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0011381-240906103802322/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.bww58x
title: Occurrence Download

description: A dataset containing 6 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Apis nuluensis Tingek, Koeniger & Koeniger, 1996"
 ]
}

 The dataset includes 6 records from 4 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0011382-240906103802322/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.11004722
title: Data for 'Global Assessment of Interannual Hazard Variability in Coastal Urban Areas and Ecosystems'

description: This dataset supports Odériz et al. (2024). 'Global Assessment of Interannual Hazard Variability in Coastal Urban Areas and Ecosystems'
DOI: 10.5281/zenodo.13744521
title: cif files and VASP files for Li6PS5X crystals and a set of isovalent analogs

description: This dataset is meant as supplementary material to the research paper titled "The Devil in the Details: Lessons from Li6PS5X for Robust High-Throughput Workflows" authored by Asif Iqbal Bhatti, Sandeep Kumar, Catharina Jaeken, Michael Sluydts, Danny E.P. Vanpoucke and Stefaan Cottenier. At the time of writing this description, the manuscript is under peer review (publication info will be added here once published). 

The data set contains cif files as well as VASP input and output for all crystals that are being discussed in this paper.
DOI: 10.5281/zenodo.13744522
title: cif files and VASP files for Li6PS5X crystals and a set of isovalent analogs

description: This dataset is meant as supplementary material to the research paper titled "The Devil in the Details: Lessons from Li6PS5X for Robust High-Throughput Workflows" authored by Asif Iqbal Bhatti, Sandeep Kumar, Catharina Jaeken, Michael Sluydts, Danny E.P. Vanpoucke and Stefaan Cottenier. At the time of writing this description, the manuscript is under peer review (publication info will be added here once published). 

The data set contains cif files as well as VASP input and output for all crystals that are being discussed in this paper.
DOI: 10.15468/dl.z8wwwd
title: Occurrence Download

description: A dataset containing 83 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Anhima cornuta (Linnaeus, 1766), Chauna chavaria (Linnaeus, 1766))",
 "Year 1990-1991"
 ]
}

 The dataset includes 83 records from 6 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0011384-240906103802322/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.4121/4012c93e-cc03-4301-b2af-cb8b3785273a
title: Data underlying the publication: The Mechanism behind Vibration Assisted Fluidization of Cohesive Micro-Silica

description: In our manuscript, we revealed the mechanism by which mechanical vibration improves/initiates the fluidization of cohesive powdersExperiments were performed, in presence and absence of mechanical vibration at various superficial gas velocitiesContains (raw) data of corresponding to DOI: 10.14356/kona.2024007:Pressure drop dataBed extension dataPrimary particle and agglomerate size distributionsX-ray images<br>
DOI: 10.4121/4012c93e-cc03-4301-b2af-cb8b3785273a.v1
title: Data underlying the publication: The Mechanism behind Vibration Assisted Fluidization of Cohesive Micro-Silica

description: In our manuscript, we revealed the mechanism by which mechanical vibration improves/initiates the fluidization of cohesive powdersExperiments were performed, in presence and absence of mechanical vibration at various superficial gas velocitiesContains (raw) data of corresponding to DOI: 10.14356/kona.2024007:Pressure drop dataBed extension dataPrimary particle and agglomerate size distributionsX-ray images<br>
DOI: 10.15468/dl.kfs2us
title: Occurrence Download

description: A dataset containing 135 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Breviceps verrucosus Rapp, 1842"
 ]
}

 The dataset includes 135 records from 11 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0011385-240906103802322/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.eb827b
title: Occurrence Download

description: A dataset containing 150 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Anhima cornuta (Linnaeus, 1766)",
 "Year 2000-2001"
 ]
}

 The dataset includes 150 records from 3 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0011386-240906103802322/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.esejhy
title: Occurrence Download

description: A dataset containing 5719 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON((-0.98349 45.9551,-0.93613 45.9551,-0.93613 45.98579,-0.98349 45.98579,-0.98349 45.9551))",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 5719 records from 30 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0011387-240906103802322/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.ujfcwn
title: Occurrence Download

description: A dataset containing 535 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Anhima cornuta (Linnaeus, 1766)",
 "Year 2010-2011"
 ]
}

 The dataset includes 535 records from 8 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0011388-240906103802322/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.gdbue6
title: Occurrence Download

description: A dataset containing 340 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON((25.3545 42.10212,25.46291 42.10212,25.46291 42.15312,25.3545 42.15312,25.3545 42.10212))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present"
 ]
}

 The dataset includes 340 records from 7 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0011389-240906103802322/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.26983549
title: dataset for study 1

description: As one of the love gods from Greek myth, Pothos represents the idea of inaccessible yet unforgettable love, a concept that mirrors the relationships formed in the Chinese Otome game between players and in-game agents. This research, which combines game ontology and the Basic Psychological Needs Theory (BPNT), explores the mechanism model of motivation for engaging in Otome games in China. Study 1 used the Structural Equation Model (SEM) and collected 759 Chinese data, constructed a model of motivation based on previous results. To address the unresolved question from Study 1, study 2 employed qualitative methods with 15 respondents to further compare virtual and real romantic relationships. Our research unravels the intricate mechanism of motivation for game engagement from a unique combination of game ontology and psychological perspective, not only contributes to the extension and potentiality of media psychology but also provides practical insights for game developers and psychologists.
DOI: 10.6084/m9.figshare.26983549.v2
title: dataset for study 1

description: As one of the love gods from Greek myth, Pothos represents the idea of inaccessible yet unforgettable love, a concept that mirrors the relationships formed in the Chinese Otome game between players and in-game agents. This research, which combines game ontology and the Basic Psychological Needs Theory (BPNT), explores the mechanism model of motivation for engaging in Otome games in China. Study 1 used the Structural Equation Model (SEM) and collected 759 Chinese data, constructed a model of motivation based on previous results. To address the unresolved question from Study 1, study 2 employed qualitative methods with 15 respondents to further compare virtual and real romantic relationships. Our research unravels the intricate mechanism of motivation for game engagement from a unique combination of game ontology and psychological perspective, not only contributes to the extension and potentiality of media psychology but also provides practical insights for game developers and psychologists.
DOI: 10.6084/m9.figshare.26983549.v1
title: dataset for study 1

description: As one of the love gods from Greek myth, Pothos represents the idea of inaccessible yet unforgettable love, a concept that mirrors the relationships formed in the Chinese Otome game between players and in-game agents. This research, which combines game ontology and the Basic Psychological Needs Theory (BPNT), explores the mechanism model of motivation for engaging in Otome games in China. Study 1 used the Structural Equation Model (SEM) and collected 759 Chinese data, constructed a model of motivation based on previous results. To address the unresolved question from Study 1, study 2 employed qualitative methods with 15 respondents to further compare virtual and real romantic relationships. Our research unravels the intricate mechanism of motivation for game engagement from a unique combination of game ontology and psychological perspective, not only contributes to the extension and potentiality of media psychology but also provides practical insights for game developers and psychologists.
DOI: 10.6084/m9.figshare.26983438
title: 数据集 1.xlsx

description: DHC 的准确阈值是使用极限法获得的。每个观察者总共经历了 19,800 次颜色刺激（6 种颜色×10 对颜色方向×33 组互补刺激×2 组交替×5 次重复）。
DOI: 10.6084/m9.figshare.26983438.v1
title: 数据集 1.xlsx

description: DHC 的准确阈值是使用极限法获得的。每个观察者总共经历了 19,800 次颜色刺激（6 种颜色×10 对颜色方向×33 组互补刺激×2 组交替×5 次重复）。
DOI: 10.18712/nsd-nsd1540-v2
title: Norwegian Fathers’ Use of Parental Leave, 1987-89

description: The project has highlighted the following issues: 
1. Which factors are important for fathers when it comes to take a paternity leave? 
2. How does the arrangement around the (paid) leave of absence affect men's use of paternity leave?
3. What do the men who take paternitiy leave experience regarding (paid) leave of absence?
DOI: 10.18712/nsd-nsd2867-v2
title: Prospects for the Norwegian Forest Sector: A Green Shift to Come?, 2018

description: BioNEXT is a three-year research project that started in 2016, which was led by the Norwegian University of Environmental and Life Sciences. In BioNEXT, researchers and business partners explored what it takes to make Norway's future bioenergy production profitable, efficient and sustainable. The background is large untapped forest resources and political visions of using these for industrial production of bioenergy. In this transition phase, the aim of BioNEXT is to provide research-based knowledge so that strategic, sustainable choices can be made.
DOI: 10.15468/dl.t3ejmz
title: Occurrence Download

description: A dataset containing 1075 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is one of (Korea, Republic of, Japan, France, Spain, Portugal, Indonesia, Algeria, Chinese Taipei)",
 "TaxonKey is Rugulopteryx okamurae (E.Y.Dawson) I.K.Hwang, W.J.Lee & H.S.Kim, 2009"
 ]
}

 The dataset includes 1075 records from 31 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0011390-240906103802322/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.