cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17028/rd.lboro.23968134.v1
title: Supplementary information files for The hamstrings to quadriceps functional ratio expressed over the full angle-angular velocity range using a limited number of data points

description: Supplementary files for article The hamstrings to quadriceps functional ratio expressed over the full angle-angular velocity range using a limited number of data pointsThe hamstring to quadriceps (H : Q) strength ratio is widely used to identify individuals at risk of sustaining hamstring strain injuries. However, its efficacy is not supported by the current evidence. Current methods for the calculation of the H : Q ratio provide only a one- or two-dimensional ratio, often ignoring fundamental muscle mechanical properties. Based on isokinetic torque measurements of the knee flexors and extensors (0-400° s<sup>-1</sup>) in 25 young, physically active males, we derived a model equation that creates a threedimensional H : Q functional ratio profile. The model robustness was tested against a different number of input torque data (8, 11, 14 and 17 pairs of points) and small perturbation of the knee joint angle data (5°). The model was consistent and behaved well under all conditions apart from the eight pairs of points (R<sup>2</sup>= 0.84-0.96; RMSE = 0.14-0.25; NRMSE = 0.12-0.27), and the H : Q functional ratio was successfully described even at angles and velocities that cannot be normally assessed with isokinetic dynamometry. Overall, our results suggest that the model can provide a fast and accurate three-dimensional description of the knee joint muscle strength balance using as few as 11 experimental data points and this could be an easy-to-employ screening tool.<br>
DOI: 10.5281/zenodo.8252543
title: Supplementary Material

description: Dataset related to publication
DOI: 10.5281/zenodo.8252542
title: Supplementary Material

description: Dataset related to publication
DOI: 10.5517/cc8rdv7
title: CCDC 260829: Experimental Crystal Structure Determination

description: Related Article: C.Mann, R.Gompper, K.Polborn|2005|CSD Communication|||
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc8r46b
title: CCDC 260561: Experimental Crystal Structure Determination

description: Related Article: C.Mann, R.Gompper, K.Polborn|2005|CSD Communication|||
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccx0d8k
title: CCDC 834528: Experimental Crystal Structure Determination

description: Related Article: Xiao-Feng Wang,Zhong-Qin Chen,Peng-Fei Yang,Yan-Fei Wang|2012|Koord.Khim.|38|847|
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccvvv9t
title: CCDC 800367: Experimental Crystal Structure Determination

description: Related Article: Hong-Hui Liu, Yi-Wen Chen, Dong-Zhao Gao|2012|Jiegou Huaxue|31|39|
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.6084/m9.figshare.23820972.v1
title: Supplementary Material for: TCN1 expression is increased in asthma

description: Introduction: Asthma is a chronic disease that affects populations worldwide. The purpose of this study was to investigate the expression of TCN1 in sputum and its correlation with inflammation and lung function in asthma. Methods: We recruited 141 subjects, detected TCN1 mRNA level by qRT-PCR, detected TCN1 protein expression by western-blot, detected TCN1 protein level by ELISA, and analyzed the correlation between TCN1 and FeNO, IgE, EOS%, lung functions and some Th2 cytokines. The diagnostic value of TCN1 was evaluated by ROC curve. The expression of TCN1 was further confirmed by human bronchial epithelial cell in vitro. Results: Compared with the health group, the expression of TCN1 in induced sputum cells increased in asthma group and was correlated with FeNO, IgE and EOS%. TCN1 level was also elevated in the induced sputum supernatant of asthma patients. The protein level of TCN1 in induced sputum supernatant was correlated with FeNO, IgE and PC-20, FEV1%pred, FEV1/FVC and some cytokines (IL-4, IL-5, IL-10, IL-13, MUC5AC). TCN1 was also differentially expressed in patients with different severity of asthma. Four weeks after ICS treatment, the expression of TCN1 in induced sputum supernatant increased. In vitro, the protein level of TCN1 in human bronchial epithelial cells’ supernatant increased after stimulated with IL-4 and IL-13. Conclusion: The expression of TCN1 was increased in asthma patients' sputum, and was positively correlated with some inflammatory markers, negatively correlated with lung function. TCN1 may be used as a potential biomarker for the diagnosis and treatment of asthma.
DOI: 10.6084/m9.figshare.23762685.v1
title: Supplementary Material for: Postoperative early body weight loss is a risk factor for recurrence in patients with pStage III gastric cancer

description: Introduction: The goal of this study was to determine whether postoperative early body weight loss (EWL) after radical gastrectomy is a risk factor for recurrence in patients with pathological stage III (pStage III) gastric cancer who received postoperative adjuvant chemotherapy, which included tegafur/gimeracil/oteracil (S-1). Methods: Patients who underwent gastrectomy for gastric cancer were identified from a prospectively managed gastric cancer database. We analyzed 58 consecutive patients who underwent radical gastrectomy with D2 lymph node dissection for confirmed pStage III gastric cancer treated postoperatively with adjuvant chemotherapy including S-1 between 2010 and 2019. Clinical and pathologic characteristics, baseline body mass index (BMI), and postoperative weights were extracted. Weight changes were evaluated from the preoperative period to the start of adjuvant chemotherapy. EWL was defined as % BMI change = (preoperative BMI – postoperative BMI at the start of adjuvant chemotherapy) × 100 / preoperative BMI. Results: Of the 58 consecutive patients who underwent radical resection for gastric cancer, 72.4% were male, with a mean age of 65.5 years, and a mean preoperative BMI of 21.2 (range 15.4–29.1) kg/m2. The degree of EWL was found to be closely correlated to compliance with adjuvant chemotherapy. Multivariate analysis by Cox proportional hazard analysis revealed that EWL was an independent factor for relapse-free survival (RFS), and patients with an EWL of 15.9% or more severe had poorer RFS. Conclusion: EWL above a certain rate at the start of adjuvant chemotherapy was a predictor of poor compliance with adjuvant chemotherapy and a high risk of disease recurrence in patients with pStage III gastric cancer.
DOI: 10.2908/ei_etea19_m
title: Euro area 19 international trade - monthly data
title: Commerce international de l'Eurozone19 - données mensuelles
title: Internationaler Handel der Euroraum19 - Monatliche Daten
DOI: 10.34740/kaggle/dsv/6313044
title: COVID Vaccination in World (updated daily)
DOI: 10.6084/m9.figshare.23758518.v1
title: Supplementary Material for: Effect of needle-to-puncture time on reperfusion outcome in acute ischemic stroke

description: Introduction To investigate the impact of time interval between start of intravenous thrombolysis (IVT) to start of endovascular thrombectomy (EVT) on stroke outcomes. Methods Data from the Quality Improvement and Clinical Research (QuICR) provincial stroke registry from Alberta, Canada was used to identify stroke patients who received IVT and EVT from January 2015 to December 2019. We assessed the impact of the time interval between IVT bolus to EVT puncture (needle-to-puncture times “NPT”) on outcomes. Radiological outcomes included successful initial recanalization (revised arterial occlusive lesion 2b–3), successful initial and final reperfusion (modified thrombolysis in cerebral infarction 2b–3). Clinical outcomes were 90-day modified Rankin Scale (mRS) and mortality. Results Of the 680 patients, 233 patients (median age 73, 41% females) received IVT+EVT. Median NPT was 38 minutes (IQR, 24–60). Arrival during working hours was independently associated with shorter NPT (P &lt; 0.001). Successful initial recanalization, initial and final reperfusion were observed in 12%, 10% and 83% of patients, respectively. NPT was not associated with initial successful recanalization (OR 0.97 for every 10-minute increase of NPT, 95% CI 0.91 – 1.04), initial successful reperfusion (OR 1.01, 95% CI 0.96 – 1.07), or final successful reperfusion (OR 1.03, 95% CI 0.97 – 1.08). Every 10-minute delay in NPT was associated with lower odds of functional independence at 90 days (mRS ≤ 2; OR 0.93; 95% CI, 0.88–0.97). Patients with shorter NPT (≤ 38 min) had lower 90-day mRS scores (median 1 vs 3; OR 0.54 [0.31–0.91]) and had lower mortality (6.1% vs 21.2%; OR, 0.23 [0.10–0.57]) than the longer NPT group. Conclusion Shorter NPT did not impact reperfusion outcomes, but was associated with better clinical outcome.
DOI: 10.6084/m9.figshare.23559966.v1
title: Supplementary Material for: Hepatic fibrosis evaluated in patients with type 2 diabetes with and without chronic kidney disease

description: Background. Non-alcoholic fatty liver disease (NAFLD), and particularly liver fibrosis, has been suggested as a risk factor of chronic kidney disease (CKD). Given that NAFLD affects every fourth person globally, better insight is needed. Our aim was to investigate the association between hepatic fibrosis and CKD in patients with type 2 diabetes and to compare different methods for diagnosing liver fibrosis in this study population. Methods. Cross-sectional study including patients with type 2 diabetes with CKD Stages 3–5 (N=50) or without CKD (N=50). CKD was defined as eGFR &lt;60 mL/min/1.73 m2 with or without proteinuria. Three methods were used to detect significant liver fibrosis defined as either ≥8 kilopascal measured by transient elastography (FibroScan®), fibrosis-4 (FIB-4) score ≥2.67 or NAFLD fibrosis score (NFS) &gt;0.675. Results. Significant liver fibrosis was found in 38% and 28% of the patients with and without CKD, respectively, using at least one of the three methods. Both FIB-4 score and NFS were significantly higher in patients with CKD (P&lt;0.0009 and P&lt;0.0001, respectively), although insignificant after adjustments for age, sex, BMI, and duration of diabetes. In patients without CKD, a significant association between steatosis and fibrosis was observed (P=0.0007). Discussion/ Conclusion. Our data do not support any strong independent association between liver fibrosis and established CKD as assessed by FibroScan, FIB-4 score and NFS, respectively.
DOI: 10.26050/wdcc/ar6.c6danrces
title: IPCC DDC: NCAR CESM2 model output prepared for CMIP6 DAMIP

description: Project: Coupled Model Intercomparison Project Phase 6 (CMIP6) datasets - These data have been generated as part of the internationally-coordinated Coupled Model Intercomparison Project Phase 6 (CMIP6; see also GMD Special Issue: http://www.geosci-model-dev.net/special_issue590.html). The simulation data provides a basis for climate research designed to answer fundamental science questions and serves as resource for authors of the Sixth Assessment Report of the Intergovernmental Panel on Climate Change (IPCC-AR6). CMIP6 is a project coordinated by the Working Group on Coupled Modelling (WGCM) as part of the World Climate Research Programme (WCRP). Phase 6 builds on previous phases executed under the leadership of the Program for Climate Model Diagnosis and Intercomparison (PCMDI) and relies on the Earth System Grid Federation (ESGF) and the Centre for Environmental Data Analysis (CEDA) along with numerous related activities for implementation. The original data is hosted and partially replicated on a federated collection of data nodes, and most of the data relied on by the IPCC is being archived for long-term preservation at the IPCC Data Distribution Centre (IPCC DDC) hosted by the German Climate Computing Center (DKRZ). The project includes simulations from about 120 global climate models and around 45 institutions and organizations worldwide. Summary: These data include the subset used by IPCC AR6 WGI authors of the datasets originally published in ESGF for 'CMIP6.DAMIP.NCAR.CESM2' with the full Data Reference Syntax following the template 'mip_era.activity_id.institution_id.source_id.experiment_id.member_id.table_id.variable_id.grid_label.version'. The CESM2 climate model, released in 2018, includes the following components: aerosol: MAM4 (same grid as atmos), atmos: CAM6 (0.9x1.25 finite volume grid; 288 x 192 longitude/latitude; 32 levels; top level 2.25 mb), atmosChem: MAM4 (same grid as atmos), land: CLM5 (same grid as atmos), landIce: CISM2.1, ocean: POP2 (320x384 longitude/latitude; 60 levels; top grid cell 0-10 m), ocnBgchem: MARBL (same grid as ocean), seaIce: CICE5.1 (same grid as ocean). The model was run by the National Center for Atmospheric Research, Climate and Global Dynamics Laboratory, 1850 Table Mesa Drive, Boulder, CO 80305, USA (NCAR) in native nominal resolutions: aerosol: 100 km, atmos: 100 km, atmosChem: 100 km, land: 100 km, landIce: 5 km, ocean: 100 km, ocnBgchem: 100 km, seaIce: 100 km.
DOI: 10.25403/upresearchdata.23956923
title: A novel approach for improving supply chain management for SARS-CoV-2 point-of-care diagnostic services in resource-limited settings

description: This was a multiphase mixed methods study consisted of three phases, starting with a geospatial analysis to assess the spatial distribution of COVID-19 point of care (POC) testing services in the Mopani District. Phase 2 involved an audit of primary healthcare (PHC) clinics providing COVID-19 POC diagnostic services to evaluate the impact of supply chain management (SCM) on accessibility and identify barriers and enablers. Based on the findings from the initial phases, Phase 3 employed a nominal group technique (NGT) to collaborate with key stakeholders in co-creating a novel approach for improving SCM systems for COVID-19 POC diagnostic services. For geospatial analysis, ArcGIS 10.8.2 software was employed to determine the following: i) the physical location of PHC clinics and district hospitals (areas of supply) ii) the population distribution (areas of demand) iii) calculated the travel distances from areas of demand to areas of supply iv) examined variations of spatial accessibility in different areas and v) identified areas with a paucity of COVID-19 diagnostic services. <br> For the audit, we utilised an audit tool and the dataset contains the supply chain management compliance score for all the audited facilities. For the NGT, we used a qualitative data analysis approach (involving key stakeholders) in the co-creation of a novel approach for improving SCM. The dataset contains barriers and strategies that the key stakeholders identified. The barriers and strategies are ranked according to priority.
DOI: 10.25403/upresearchdata.23956923.v1
title: A novel approach for improving supply chain management for SARS-CoV-2 point-of-care diagnostic services in resource-limited settings

description: This was a multiphase mixed methods study consisted of three phases, starting with a geospatial analysis to assess the spatial distribution of COVID-19 point of care (POC) testing services in the Mopani District. Phase 2 involved an audit of primary healthcare (PHC) clinics providing COVID-19 POC diagnostic services to evaluate the impact of supply chain management (SCM) on accessibility and identify barriers and enablers. Based on the findings from the initial phases, Phase 3 employed a nominal group technique (NGT) to collaborate with key stakeholders in co-creating a novel approach for improving SCM systems for COVID-19 POC diagnostic services. For geospatial analysis, ArcGIS 10.8.2 software was employed to determine the following: i) the physical location of PHC clinics and district hospitals (areas of supply) ii) the population distribution (areas of demand) iii) calculated the travel distances from areas of demand to areas of supply iv) examined variations of spatial accessibility in different areas and v) identified areas with a paucity of COVID-19 diagnostic services. <br> For the audit, we utilised an audit tool and the dataset contains the supply chain management compliance score for all the audited facilities. For the NGT, we used a qualitative data analysis approach (involving key stakeholders) in the co-creation of a novel approach for improving SCM. The dataset contains barriers and strategies that the key stakeholders identified. The barriers and strategies are ranked according to priority.
DOI: 10.5281/zenodo.8252528
title: Results of the CCM SOCOLv3 runs with and without orographic gravity waves (OGW) parameterizations

description: 1. Model run without any OGW parameterization: T_no_OGW.nc – Temperature (K) U_no_OGW.nc – Eastward zonal wind (m/s) 2. Model run with the OGW parameterization of Lott and Miller: T_Lott_Miller.nc – Temperature (K) U_Lott_Miller.nc – Eastward zonal wind (m/s) 3. Model run with the OGW parameterization of the Saint-Petersburg University (SPBU): T_SPBU.nc – Temperature (K) U_SPBU.nc – Eastward zonal wind (m/s) ------------------------------------------------------------------------------------------------- (monthly and zonal mean values averaged over 2009-2018 time period)
DOI: 10.5281/zenodo.8252527
title: Results of the CCM SOCOLv3 runs with and without orographic gravity waves (OGW) parameterizations

description: 1. Model run without any OGW parameterization: T_no_OGW.nc – Temperature (K) U_no_OGW.nc – Eastward zonal wind (m/s) 2. Model run with the OGW parameterization of Lott and Miller: T_Lott_Miller.nc – Temperature (K) U_Lott_Miller.nc – Eastward zonal wind (m/s) 3. Model run with the OGW parameterization of the Saint-Petersburg University (SPBU): T_SPBU.nc – Temperature (K) U_SPBU.nc – Eastward zonal wind (m/s) ------------------------------------------------------------------------------------------------- (monthly and zonal mean values averaged over 2009-2018 time period)
DOI: 10.6084/m9.figshare.23436521.v1
title: Supplementary Material for: Association of intradialytic hypertension with future cardiovascular events and mortality in hemodialysis patients: effects of ambulatory blood pressure

description: Introduction: Intradialytic-hypertension (IDHTN) is associated with increased risk of adverse outcomes. Patients with IDHTN have higher 44-hour blood pressure (BP) than patients without this condition. Whether the excess risk in these patients is due to the BP rise during dialysis per se or on elevated 44-h BP or other co-morbid conditions is uncertain. This study evaluated the association of IDHTN with cardiovascular events and mortality and the influence of ambulatory BP and other cardiovascular risk factors on these associations. Methods: 242 hemodialysis patients with valid 48-h ABPM (Mobil-O-Graph-NG) were followed for a median of 45.7 months. IDHTN was defined as: SBP rise ≥10mmHg from pre- to post-dialysis and post-dialysis SBP≥150mmHg. The primary end-point was all-cause mortality; the secondary endpoint was a composite of cardiovascular death, non-fatal myocardial infarction, non-fatal stroke, resuscitation-after cardiac-arrest, heart-failure-hospitalization, coronary or peripheral revascularization. Results: Cumulative freedom from both the primary and secondary endpoint was significantly lower for IDHTN patients (logrank-p=0.048 and 0.022, respectively), corresponding to higher risks for all-cause-mortality (HR=1.566; 95%CI [1.001, 2.450]) and the composite cardiovascular outcome (HR=1.675; 95%CI [1.071, 2.620]) in these individuals. However, the observed associations lost statistical significance after adjustment for 44-h SBP (HR=1.529; 95%CI [0.952, 2.457] and HR=1.388; 95%CI [0.866, 2.225], respectively). In the final model after additional adjustment for 44-h SBP, interdialytic-weight-gain, age, history of coronary-artery-disease, heart-failure, diabetes and 44-h PWV, the association of IDHTN with the outcomes was also not significant and the respective HRs were 1.377 (95%CI [0.836, 2.268]) and 1.451 (95%CI [0.891, 2.364]). Conclusions: IDHTN patients had higher risk for mortality and cardiovascular outcomes but this risk is at least partly confounded by the elevated BP levels during the interdialytic period.
DOI: 10.6084/m9.figshare.23652573.v1
title: Supplementary Material for: Comparison of clinical course and outcomes between dilated and hypokinetic non-dilated cardiomyopathy

description: Background: By definition, dilated cardiomyopathy (DCM) is characterized by enlargement of the left ventricular (LV) cavity, and systolic dysfunction. However, in 2016 ESC introduced a new clinical entity – hypokinetic non-dilated cardiomyopathy (HNDC). HNDC is defined as LV systolic dysfunction without LV dilatation. However, the diagnosis of HNDC has so far rarely been made by a cardiologist, and it is unknown whether “classic” DCM differs from HNDC in terms of clinical course and outcomes. Objectives: Comparison of heart failure profiles and outcomes between patients with “classic” dilated (DCM) and hypokinetic non-dilated cardiomyopathies (HNDC). Method: We retrospectively analysed 785 DCM patients, defined as impaired left ventricle (LV) systolic function (ejection fraction [LVEF] &lt;45%) in the absence of coronary artery disease, valve disease, congenital heart disease and severe arterial hypertension. “Classic” DCM was diagnosed when LV dilatation was present (LV end-diastolic diameter &gt;52mm/58mm in women/men); otherwise, HNDC was diagnosed. After 47±31 months, the all-cause mortality and composite endpoint (all-cause mortality, heart transplant – HTX, left ventricle assist device implantation - LVAD) were assessed. Results: There were 617 (79%) patients with LV dilatation. Patients with “classic” DCM differed from HNDC in terms of clinically relevant parameters [hypertension (47% vs. 64%, p=0.008), ventricular tachyarrhythmias (29% vs. 15%, p=0.007), NYHA class (2.5±0.9 vs. 2.2±0.8, p=0.003), had lower cholesterol (LDL: 2.9±1.0 vs. 3.2±1.1mmol/l, p=0.049) and higher NT-proBNP (3351±5415 vs. 2563±8584pg/ml, p=0.0001); and required higher diuretics dosages (57.8±89.5 vs. 33.7±48.7mg/day, p=&lt;0.0001). All of their chambers were larger (LVEDd: 68.3±4.5 vs. 52.7±3.5mm, p&lt;0.0001) and they had lower LVEF (25.2±9.4 vs. 36.6±11.7%, p&lt;0.0001). During the follow-up, there were 145 (18%) composite endpoints (“classic” DCM vs. HNDC: 122 [20%] vs. 26 [18%], p=0.22): deaths (97 [16%] vs. 24 [14%], p=0.67), HTX (17 [4%] vs. 4 [4%], p=0.97) and LVAD (19 [5%] vs 0 [0%], p=0.03). Both groups did not differ in terms of all-cause mortality (p=0.70), CV mortality (p=0.37) and composite endpoint (p=0.26). Conclusions: LV dilatation was absent in more than one-fifth of DCM patients. HNDC patients had less severe HF symptoms, less advanced cardiac remodelling, and required lower diuretics dosages. On the other hand, “classic” DCM and HNDC patients did not differ in terms of all-cause mortality, CV mortality and composite endpoint.