cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q2s46vpq
title: BindingDB Entry 50003191: Discovery and Characterization of AZD6738, a Potent Inhibitor of Ataxia Telangiectasia Mutated and Rad3 Related (ATR) Kinase with Application as an Anticancer Agent.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2, Cytochrome P450 1A, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A, DNA-dependent protein kinase, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial, Serine-protein kinase ATM, Serine/threonine-protein kinase ATR, and mTOR/FKBP12A/FKBP12B, Uniprot A0A024R3C7, C1ID52, P05177, P08684, P10635, P11712, P33261, P40989, P42336, P42345, P78527, Q13315, Q13535, Q6GRK0, and S5RV20
DOI: 10.7270/q2nc63xx
title: BindingDB Entry 50003192: Potent, Irreversible Inhibition of Human Carboxylesterases by Tanshinone Anhydrides Isolated from Salvia miltiorrhiza ("Danshen").

description: Small molecule binding data for protein Acyl coenzyme A:cholesterol acyltransferase and Cholinesterases; ACHE & BCHE, Uniprot P06276, P22303, and P23141
DOI: 10.7270/q2hq42kg
title: BindingDB Entry 50003193: NMR-Based Investigation of Hydrogen Bonding in a Dihydroanthracen-1(4 H)one from Rubia philippinensis and Its Soluble Epoxide Hydrolase Inhibitory Potential.

description: Small molecule binding data for protein EBifunctional epoxide hydrolase 2, Uniprot P34913
DOI: 10.7270/q2cz39vr
title: BindingDB Entry 50003194: Stereoselective Synthesis of the Isomers of Notoincisol A: Assigment of the Absolute Configuration of this Natural Product and Biological Evaluation.

description: Small molecule binding data for protein Peroxisome proliferator-activated receptor, Uniprot P37231
DOI: 10.7270/q2862k4r
title: BindingDB Entry 50003195: Molecular Basis for Multiple Omapatrilat Binding Sites within the ACE C-Domain: Implications for Drug Design.

description: Small molecule binding data for protein Angiotensin-converting enzyme, Uniprot P12821
DOI: 10.7270/q24f1td1
title: BindingDB Entry 50003196: Neolymphostin A Is a Covalent Phosphoinositide 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Dual Inhibitor That Employs an Unusual Electrophilic Vinylogous Ester.

description: Small molecule binding data for protein PIK3CG/PIK3R1, Phosphatidylinositol 3-kinase regulatory subunit beta/Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform/gamma isoform, SRC, and mTOR/FKBP12A/FKBP12B, Uniprot A0A024R720, A0A0S2Z3Y8, A0A2K8FKV1, O00329, P06239, P42336, P42338, P42345, and P48736
DOI: 10.7270/q20p12pp
title: BindingDB Entry 50003197: Total Synthesis of Xanthoangelol B and Its Various Fragments: Toward Inhibition of Virulence Factor Production of Staphylococcus aureus.

description: Small molecule binding data for protein Histidine protein kinase SaeS and Receptor-histidine kinase AgrC, Uniprot O07911 and Q2G2U1
DOI: 10.7270/q22n550r
title: BindingDB Entry 50003177: Decision Making in Medicinal Chemistry: The Power of Our Intuition.

description: Small molecule binding data for protein Estrogen receptor, Uniprot Q7LCB3 and Q92731
DOI: 10.7270/q2vx0k6d
title: BindingDB Entry 50003198: Overcoming Time-Dependent Inhibition (TDI) of Cytochrome P450 3A4 (CYP3A4) Resulting from Bioactivation of a Fluoropyrimidine Moiety.

description: Small molecule binding data for protein Beta-secretase (BACE) and Cytochrome P450 3A, Uniprot A0A024R3D7, P08684, P56817, and Q6GRK0
DOI: 10.7270/q2r49tgf
title: BindingDB Entry 50003202: Structure-Based Engineering of Irreversible Inhibitors against Histone Lysine Demethylase KDM5A.

description: Small molecule binding data for protein Lysine-specific demethylase 4A, Lysine-specific demethylase 5A/5B, and Lysine-specific demethylase 6A, Uniprot O15550, O75164, and P29375
DOI: 10.7270/q2gq71gj
title: BindingDB Entry 50003204: Structural Basis of Sirtuin 6 Inhibition by the Hydroxamate Trichostatin A: Implications for Protein Deacylase Drug Development.

description: Small molecule binding data for protein NAD-dependent deacetylase sirtuin 1 and Sirtuin-6 (SIRT6), Uniprot A0A024QZQ1, Q8N6T7, and Q96EB6
DOI: 10.7270/q2mg7s6w
title: BindingDB Entry 50003203: Hydroxybiphenylamide GroEL/ES Inhibitors Are Potent Antibacterials against Planktonic and Biofilm Forms of Staphylococcus aureus.

description: Small molecule binding data for protein 10 kDa chaperonin, 60 kDa heat shock protein, mitochondrial, and Thiosulfate sulfurtransferase, Uniprot A0A024R3X4, A0A384NKQ2, P10809, Q16762, and Q7BGE6
DOI: 10.7270/q2bz68rt
title: BindingDB Entry 50003205: First Report of Plant-Derived β-Sitosterol with Antithrombotic, in Vivo Anticoagulant, and Thrombus-Preventing Activities in a Mouse Model.

description: Small molecule binding data for protein Thrombin and coagulation factor X, Uniprot P00734
DOI: 10.7270/q23f4sbj
title: BindingDB Entry 50003207: Optimization of Phenyl Indole Inhibitors of the AAA+ ATPase p97.

description: Small molecule binding data for protein Valosin containing protein, p97 subunit, Uniprot P55072 and V9HW80
DOI: 10.7270/q2765j1t
title: BindingDB Entry 50003206: Diterpenoids from Euphorbia dulcis with Potassium Ion Channel Inhibitory Activity with Selective G Protein-Activated Inwardly Rectifying Ion Channel (GIRK) Blocking Effect.

description: Small molecule binding data for protein G protein-activated inward rectifier potassium channel 4, Uniprot A0A5J6E2W8 and P48544
DOI: 10.7270/q2zp48ts
title: BindingDB Entry 50003208: Discovery and Pharmacology of a Novel Somatostatin Subtype 5 (SSTR5) Antagonist: Synergy with DPP-4 Inhibition.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A, Prostanoid DP receptor, Sodium channel protein type 5 subunit alpha, Somatostatin receptor, Somatostatin receptor type 1, Somatostatin receptor type 2, Somatostatin receptor type 3, Somatostatin receptor type 4, Somatostatin receptor type 5, Voltage-gated calcium channel, and Voltage-gated potassium channel beta subunit Mink, Uniprot C1ID52, C7S316, O08858, P08684, P10635, P11712, P15382, P30872, P30874, P31391, P32745, P35346, P40989, Q13258, Q13936, Q14524, Q6GRK0, and S5RV20
DOI: 10.7270/q2q81gsc
title: BindingDB Entry 50003211: 2-Aminoadipic Acid-C(O)-Glutamate Based Prostate-Specific Membrane Antigen Ligands for Potential Use as Theranostics.

description: Small molecule binding data for protein Glutamate carboxypeptidase II, Uniprot Q04609
DOI: 10.7270/q2v127h3
title: BindingDB Entry 50003210: Optimization of Preclinical Metabolism for Somatostatin Receptor Subtype 5-Selective Antagonists.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2, Sodium channel protein type 5 subunit alpha, Somatostatin receptor, Somatostatin receptor type 5, and Voltage-gated calcium channel, Uniprot O08858, P35346, P40989, Q13936, and Q14524
DOI: 10.7270/q2kh0r22
title: BindingDB Entry 50003212: Discovery of 4-Azaindole Inhibitors of TGFβRI as Immuno-oncology Agents.

description: Small molecule binding data for protein Activin receptor type-1B, Cytochrome P450 1A, Cytochrome P450 2C19, Cytochrome P450 2C8, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A, Mitogen-activated protein kinase 14, TGF-beta receptor type II, and TGF-beta receptor type-1, Uniprot A0A024RD15, A3QNQ0, C1ID52, P05177, P08684, P10632, P10635, P11712, P33261, P36896, P36897, P37173, Q16539, Q5T7S2, Q6GRK0, and S5RV20
DOI: 10.7270/q2668gw1
title: BindingDB Entry 50003216: Anti-inflammatory Activity of Natural Geranylated Flavonoids: Cyclooxygenase and Lipoxygenase Inhibitory Properties and Proteomic Analysis.

description: Small molecule binding data for protein Arachidonate 5-lipoxygenase, Prostaglandin E synthase/G/H synthase 2, and Prostaglandin G/H synthase (cyclooxygenase), Uniprot P05979, P09917, and P35354
DOI: 10.7270/q2fr00bq
title: BindingDB Entry 50003213: Discovery of JND3229 as a New EGFR

description: Small molecule binding data for protein Epidermal growth factor receptor, Uniprot P00533
DOI: 10.7270/q29z97mf
title: BindingDB Entry 50003214: ALK5 kinase inhibitory activity and synthesis of 2,3,4-substituted 5,5-dimethyl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazoles.

description: Small molecule binding data for protein CDK2/CycE, TGF-beta receptor type-1, and Tyrosine-protein kinase ABL1, Uniprot A0A024RB77, P00520, P24864, P24941, P36897, and Q5T7S2
DOI: 10.7270/q22f7r5q
title: BindingDB Entry 50003217: The Berkeleylactones, Antibiotic Macrolides from Fungal Coculture.

description: Small molecule binding data for protein Matrix metalloproteinase (2 and 3), Uniprot P08254
DOI: 10.7270/q2xs5z29
title: BindingDB Entry 50003218: Synthesis and biological evaluation of morpholine-substituted diphenylpyrimidine derivatives (Mor-DPPYs) as potent EGFR T790M inhibitors with improved activity toward the gefitinib-resistant non-small cell lung cancers (NSCLC).

description: Small molecule binding data for protein Epidermal growth factor receptor, Uniprot P00533
DOI: 10.7270/q2p84fmj
title: BindingDB Entry 50003220: Isolation and structure determination of nostocyclopeptides A1 and A2 from the terrestrial cyanobacterium Nostoc sp. ATCC53789.

description: Small molecule binding data for protein Papain, Plasminogen, and Thrombin and coagulation factor X, Uniprot P00734, P00747, and P00784
DOI: 10.7270/q2t156b8
title: BindingDB Entry 50003219: Recent updates on third generation EGFR inhibitors and emergence of fourth generation EGFR inhibitors to combat C797S resistance.

description: Small molecule binding data for protein Epidermal growth factor receptor, Uniprot P00533
DOI: 10.7270/q2dr2z6z
title: BindingDB Entry 50003222: Recent advances (2015-2016) in anticancer hybrids.

description: Small molecule binding data for protein Epidermal growth factor receptor, Tyrosinase, and Vascular endothelial growth factor receptor 1, Uniprot L7RSL3, O42713, P00533, and P17948
DOI: 10.7270/q2jh3pwt
title: BindingDB Entry 50003221: How to train your inhibitor: Design strategies to overcome resistance to Epidermal Growth Factor Receptor inhibitors.

description: Small molecule binding data for protein Epidermal growth factor receptor and Receptor tyrosine-protein kinase erbB-2, Uniprot P00533, P04626, and X5DNK3
DOI: 10.7270/q29026gx
title: BindingDB Entry 50003224: Targeting Eph/ephrin system in cancer therapy.

description: Small molecule binding data for protein Ephrin receptor, Ephrin type-A receptor 2, Ephrin type-B receptor 2, and Ephrin type-B receptor 4, Uniprot A0A024QZA8, A1MA61, P29317, P29323, P54760, P54764, Q03145, and Q541P7
DOI: 10.7270/q2571fqr
title: BindingDB Entry 50003225: Indole-fused azepines and analogues as anticancer lead molecules: Privileged findings and future directions.

description: Small molecule binding data for protein Cyclin-Dependent Kinase 1 (CDK1) and Glycogen Synthase Kinase-3, beta, Uniprot P06493, P14635, and P18266
DOI: 10.7270/q21j9dg3
title: BindingDB Entry 50003226: From bench (laboratory) to bed (hospital/home): How to explore effective natural and synthetic PAK1-blockers/longevity-promoters for cancer therapy.

description: Small molecule binding data for protein Ephrin type-A receptor 3, Histone deacetylase, Mitogen-activated protein kinase kinase kinase 11, PAK 1/CDC42, Prostaglandin E synthase/G/H synthase 2, Protein kinase C (PKC), Serine/threonine-protein kinase PAK 1, Tyrosine-protein kinase Fyn, and p21-Activated kinase 3 (PAK3), Uniprot A0A024QZ26, A0A024R5E6, A0A024R5P0, O15379, O75914, O88643, P06241, P09217, P29319, P35354, P56524, Q13153, Q13547, Q16584, Q6IT96, Q8WUI4, Q92769, Q969S8, Q96DB2, Q9BY41, Q9UBN7, Q9UKV0, and Q9UQL6
DOI: 10.7270/q2ws8wzz
title: BindingDB Entry 50003228: Recent developments in small molecule therapies for renal cell carcinoma.

description: Small molecule binding data for protein Focal adhesion kinase 1/vascular endothelial growth factor receptor 3, Vascular endothelial growth factor receptor 1, and Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2), Uniprot L7RSL3, P17948, P35916, and P35968
DOI: 10.7270/q2s1856w
title: BindingDB Entry 50003229: Structural insights of cyclin dependent kinases: Implications in design of selective inhibitors.

description: Small molecule binding data for protein CDK2/Cyclin O, Cyclin-T1/Cyclin-dependent-like kinase 5, Cyclin-dependent kinase 1, Cyclin-dependent kinase 4, Cyclin-dependent kinase 6, and Cyclin-dependent kinase 9, Uniprot A0A024R880, A0A024RB77, A0A024RBB6, A0A090N7W4, P06493, P11802, P24941, P50750, Q00534, and Q00535
DOI: 10.7270/q2hh6nrf
title: BindingDB Entry 50003231: 1,3,5-Triazines: A promising scaffold for anticancer drugs development.

description: Small molecule binding data for protein CDK2/CycE, Cyclin-Dependent Kinase 2 (CDK2), Cyclin-Dependent Kinase 5 (CDK5), Cyclin-Dependent Kinase 7 (CDK7), Cyclin-Dependent Kinase 9 (CDK9), Histamine H4 receptor, PIK3CG/PIK3R1, Serine/threonine-protein kinase PAK 4, Thymidine phosphorylase, and Ubiquitin-conjugating enzyme E2 B, Uniprot A0A024R0J1, A0A024R720, A0A024R880, A0A024RB77, A0A090N7W4, A0A0S2Z3F9, A0A2X0SFG1, E5KRG5, O60563, O96013, P19971, P20248, P24864, P24941, P27986, P48736, P50613, P50750, P51946, P63146, Q00535, Q15078, and Q9H3N8
DOI: 10.7270/q2n87dg5
title: BindingDB Entry 50003230: Covalent binding design strategy: A prospective method for discovery of potent targeted anticancer agents.

description: Small molecule binding data for protein Fibroblast growth factor receptor 1, TEC family kinase, and Tyrosine-protein kinase BTK, Uniprot P11362, P51813, and Q06187
DOI: 10.7270/q2cr5x14
title: BindingDB Entry 50003232: Targeting Wnt-driven cancers: Discovery of novel tankyrase inhibitors.

description: Small molecule binding data for protein Poly [ADP-ribose] polymerase 1, Poly [ADP-ribose] polymerase 2, Poly [ADP-ribose] polymerase tankyrase-1, and Poly [ADP-ribose] polymerase tankyrase-2, Uniprot A0A024R3T8, O95271, P09874, Q9H2K2, and Q9UGN5
DOI: 10.7270/q2805593
title: BindingDB Entry 50003233: Rational design and screening of peptide-based inhibitors of heat shock factor 1 (HSF1).

description: Small molecule binding data for protein Heat shock factor protein 1, Uniprot Q00613
DOI: 10.7270/q24b341j
title: BindingDB Entry 50003234: Harnessing pyrrolidine iminosugars into dimeric structures for the rapid discovery of divalent glycosidase inhibitors.

description: Small molecule binding data for protein Beta-galactosidase/Glucosylceramidase, Uniprot Q58D55
DOI: 10.7270/q20k2c9t
title: BindingDB Entry 50003235: Replacement of Arg with Nle and modified D-Phe in the core sequence of MSHs, Ac-His-D-Phe-Arg-Trp-NH

description: Small molecule binding data for protein Melanocortin receptor (M4 and M5), Melanocortin receptor 3, and Melanocyte-stimulating hormone receptor, Uniprot P32245, P33032, P41968, Q01726, and Q1JUL4
DOI: 10.7270/q2vt1vt4
title: BindingDB Entry 50003236: Design, synthesis and biological evaluation of novel xanthine oxidase inhibitors bearing a 2-arylbenzo[b]furan scaffold.

description: Small molecule binding data for protein Xanthine dehydrogenase, Uniprot P80457
DOI: 10.7270/q2r2143h
title: BindingDB Entry 50003237: Screening serine/threonine and tyrosine kinase inhibitors for histidine kinase inhibition.

description: Small molecule binding data for protein Sensor protein kinase WalK, Uniprot Q9RDT3
DOI: 10.7270/q2m90ccs
title: BindingDB Entry 50003238: Design and biological evaluation of tetrahydro-β-carboline derivatives as highly potent histone deacetylase 6 (HDAC6) inhibitors.

description: Small molecule binding data for protein Cereblon/Histone deacetylase 1, Cereblon/Histone deacetylase 2, Histone deacetylase 10, Histone deacetylase 4, Histone deacetylase 6, and Histone deacetylase 8, Uniprot A0A024QZ26, P56524, Q13547, Q6IT96, Q92769, Q969S8, Q9BY41, and Q9UBN7
DOI: 10.7270/q2gh9mnh
title: BindingDB Entry 50003239: Synthesis and biological evaluation of β

description: Small molecule binding data for protein Adrenergic receptor and Beta-2 adrenergic receptor and beta-3 adrenergic receptor, Uniprot A8KAG8, P07550, P08588, P13945, and X5DQM5
DOI: 10.7270/q2736tm3
title: BindingDB Entry 50003241: Design, synthesis and biological evaluation of a series of novel 2-benzamide-4-(6-oxy-N-methyl-1-naphthamide)-pyridine derivatives as potent fibroblast growth factor receptor (FGFR) inhibitors.

description: Small molecule binding data for protein Bcr-Abl, Ephrin type-A receptor 2, Epidermal growth factor receptor, Fibroblast growth factor receptor 1, Fibroblast growth factor receptor 2, Fibroblast growth factor receptor 3, Fibroblast growth factor receptor 4, Insulin-like growth factor I receptor, Proto-oncogene tyrosine-protein kinase Src, Receptor protein-tyrosine kinase erbB-4, Receptor tyrosine-protein kinase erbB-2, Tyrosine-protein kinase receptor FLT3, Vascular endothelial growth factor receptor 1, and Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2), Uniprot A0A024QZA8, A0A024R8E2, L7RSL3, P00519, P00533, P04626, P08069, P11274, P11362, P12931, P17948, P21802, P22455, P22607, P29317, P35968, P36888, Q15303, and X5DNK3
DOI: 10.7270/q2br8vwb
title: BindingDB Entry 50003240: From hit to lead: Structure-based discovery of naphthalene-1-sulfonamide derivatives as potent and selective inhibitors of fatty acid binding protein 4.

description: Small molecule binding data for protein Fatty acid binding protein muscle and Fatty acid-binding protein 4 (FABP4), Uniprot A0A384MDY5, E7DVW4, P05413, and P15090
DOI: 10.7270/q23b62v9
title: BindingDB Entry 50003242: A comparative study of non-native N-acyl l-homoserine lactone analogs in two Pseudomonas aeruginosa quorum sensing receptors that share a common native ligand yet inversely regulate virulence.

description: Small molecule binding data for protein PhzR and Transcriptional activator protein lasR, Uniprot P25084 and Q9RMS5
DOI: 10.7270/q2zk5kc1
title: BindingDB Entry 50003243: SAR studies on truxillic acid mono esters as a new class of antinociceptive agents targeting fatty acid binding proteins.

description: Small molecule binding data for protein Fatty acid binding protein muscle, Fatty acid-binding protein 5 (FABP5), and Fatty acid-binding protein, brain, Uniprot A0A384MDY5, E7DVW5, O15540, P05413, and Q01469
DOI: 10.7270/q2tt4tn9
title: BindingDB Entry 50003244: Design, synthesis, molecular modeling and anti-proliferative evaluation of novel quinoxaline derivatives as potential DNA intercalators and topoisomerase II inhibitors.

description: Small molecule binding data for protein Topoisomerase I/II, Uniprot P11388
DOI: 10.7270/q2q242x8
title: BindingDB Entry 50003245: Rational design of mitochondria-targeted pyruvate dehydrogenase kinase 1 inhibitors with improved selectivity and antiproliferative activity.

description: Small molecule binding data for protein 3-phosphoinositide dependent protein kinase-1, Uniprot O15530
DOI: 10.7270/q2fj2kg7
title: BindingDB Entry 50003247: Structure-based discovery of selective BRPF1 bromodomain inhibitors.

description: Small molecule binding data for protein Bromodomain-containing protein 4, Bromodomain-containing protein 9, Peregrin, and Transcription intermediary factor 1-alpha, Uniprot O15164, O60885, P55201, and Q9H8M2
DOI: 10.7270/q2k93b6z
title: BindingDB Entry 50003246: Surmounting the resistance against EGFR inhibitors through the development of thieno[2,3-d]pyrimidine-based dual EGFR/HER2 inhibitors.

description: Small molecule binding data for protein Epidermal growth factor receptor and Receptor tyrosine-protein kinase erbB-2, Uniprot P00533, P04626, and X5DNK3
DOI: 10.7270/q29w0j57
title: BindingDB Entry 50003249: Molecular dynamics simulations of viral neuraminidase inhibitors with the human neuraminidase enzymes: Insights into isoenzyme selectivity.

description: Small molecule binding data for protein Sialidase 1, Sialidase 2, Sialidase 3, and Sialidase 4, Uniprot B3KR54, Q5JQI0, Q8WWR8, Q99519, Q9UQ49, and Q9Y3R4
DOI: 10.7270/q22b91qx
title: BindingDB Entry 50003251: Targeting prohibitin with small molecules to promote melanogenesis and apoptosis in melanoma cells.

description: Small molecule binding data for protein Prohibitin-2, Uniprot O35129 and Q3V235
DOI: 10.7270/q2639sf8
title: BindingDB Entry 50003250: Design and biological evaluation of novel triaryl pyrazoline derivatives with dioxane moiety for selective BRAF

description: Small molecule binding data for protein BRAF/CRAF, Dual specificity mitogen-activated protein kinase kinase; MEK1/2, Mitogen-activated protein kinase 14, Mitogen-activated protein kinase 8/9, RAF proto-oncogene serine/threonine-protein kinase, and Serine/threonine-protein kinase B-raf, Uniprot A0A024RD15, A4QPA9, L7RRS6, P04049, P15056, P28028, P36507, P45983, Q02750, and Q16539
DOI: 10.7270/q2xk8j7n
title: BindingDB Entry 50003252: Fibrogenic Disorders in Human Diseases: From Inflammation to Organ Dysfunction.

description: Small molecule binding data for protein Angiotensin II receptor, CREB-binding protein/Histone acetyltransferase p300, JNK2/JNK3, MAP kinase ERK1, Mitogen-activated protein kinase 10, Mitogen-activated protein kinase 14, Mitogen-activated protein kinase 8/9, Rho-associated protein kinase 1, Rho-associated protein kinase 2, Sphingosine 1-phosphate receptor 2 (S1P2), Sphingosine 1-phosphate receptor Edg-5/Sphingosine 1-phosphate receptor Edg-3, Sphingosine kinase 1, Sphingosine kinase types 2 (SphK2), Tankyrase 1/2, Tyrosine-protein kinase JAK1, Tyrosine-protein kinase JAK2, and Tyrosine-protein kinase JAK3, Uniprot A0A024QZH5, A0A024R7B2, A0A024R7M7, A0A024RD15, A0A2P9DU05, L7RXH5, O60674, O75116, O95136, O95271, P23458, P27361, P30556, P45983, P45984, P47752, P50052, P52333, P53779, Q13464, Q16539, Q53YY0, Q53ZR5, Q92793, Q9H2K2, Q9NRA0, and Q9NYA1
DOI: 10.7270/q2p271sw
title: BindingDB Entry 50003254: 4-(Phenoxy) and 4-(benzyloxy)benzamides as potent and selective inhibitors of mono-ADP-ribosyltransferase PARP10/ARTD10.

description: Small molecule binding data for protein Mono [ADP-ribose] polymerase PARP16, Poly [ADP-ribose] polymerase 1, Poly [ADP-ribose] polymerase 10, Poly [ADP-ribose] polymerase 12, Poly [ADP-ribose] polymerase 14, Poly [ADP-ribose] polymerase 15, Poly [ADP-ribose] polymerase 2, Poly [ADP-ribose] polymerase 4, Poly [ADP-ribose] polymerase tankyrase-1, Poly [ADP-ribose] polymerase tankyrase-2, and Protein mono-ADP-ribosyltransferase PARP3, Uniprot A0A024R318, A0A024R3T8, A4D1T0, O95271, P09874, Q460N3, Q460N5, Q53GL7, Q8N5Y8, Q9H0J9, Q9H2K2, Q9UGN5, Q9UKK3, and Q9Y6F1
DOI: 10.7270/q2st7shx
title: BindingDB Entry 50003253: Discovery of a potent glucokinase activator with a favorable liver and pancreas distribution pattern for the treatment of type 2 diabetes mellitus.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2, Uniprot P40989
DOI: 10.7270/q2j9692k
title: BindingDB Entry 50003255: Synthesis and anticancer activity of new dihydropyrimidinone derivatives.

description: Small molecule binding data for protein Kinesin-like protein 1, Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2), and mTOR/FKBP12A/FKBP12B, Uniprot P35968, P42345, and P52732
DOI: 10.7270/q28w3h1v
title: BindingDB Entry 50003257: Current progress on antioxidants incorporating the pyrazole core.

description: Small molecule binding data for protein Tyrosinase and Xanthine dehydrogenase, Uniprot O42713 and P47989
DOI: 10.7270/q2dn47r5
title: BindingDB Entry 50003256: Synthesis and biological evaluation of magnolol derivatives as melatonergic receptor agonists with potential use in depression.

description: Small molecule binding data for protein Melatonin receptor, Uniprot P48039 and P49286