cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.10648067
title: Dataset

description: This dataset shows the clutch size for the Buceroti suborder in the Bucerotiformes order. This suborder contains two families: the Bucorvidae and the Bucerotidae. All member of the suborder are Hornbill birds. I used these factors for the dataset as one has not been previously compiled before. I also used clutch size specifically as it is a useful numerical representative of breeding success in birds, as it can indicate factors such as resource and/or energetic availability for breeding birds.

During the literature search I searched on Google Scholar for each species in the Buceroti suborder and tried to find papers published which had numerical clutch size data. I also aimed to only use papers with data which is from later than 2000 to ensure the data is more recent and comparable between each species. There is, however, one species (Ceratogymna atrata) which I was unable to find a later dataset for on clutch size, so it is prior to 2000.

The clutch size data represents the mean number of eggs laid per breeding pair in a single brood for each species. I was unable to find Location data in the form of latitudinal and longitudinal co-ordinates, so the location data shown simply states the range of the species across the world.

Reference List:

Carstens, K.F., Kassanjee, R., Little, R.M., Ryan, P.G. and Hockey, P.A., 2019. The effects of weather, group size and type of nest on the timing of egg-laying in the Southern Ground-hornbill Bucorvus leadbeateri. Journal of Ornithology, 160, pp.633-640.

 Jetz, W., Sekercioglu, C.H. and Böhning-Gaese, K., 2008. The worldwide variation in avian clutch size across species and space. PLoS biology, 6(12), p.e303

 Phillimore, A.B., Freckleton, R.P., Orme, C.D.L. and Owens, I.P., 2006. Ecology predicts large-scale patterns of phylogenetic diversification in birds. The American Naturalist, 168(2), pp.220-229.

 Poulsen, H., 1970. Nesting Behaviour of the Black-Casqued Hornbill Ceratogymna atrata (Temm.) and the Great Hornbill Buceros bicornis L. Ornis Scandinavica, pp.11-15.

 Stander, M.C., Van de Ven, T.M. and Engelbrecht, D., 2004. Observations of nesting strategies of three African hornbill species.
DOI: 10.5281/zenodo.10648068
title: Dataset

description: This dataset shows the clutch size for the Buceroti suborder in the Bucerotiformes order. This suborder contains two families: the Bucorvidae and the Bucerotidae. All member of the suborder are Hornbill birds. I used these factors for the dataset as one has not been previously compiled before. I also used clutch size specifically as it is a useful numerical representative of breeding success in birds, as it can indicate factors such as resource and/or energetic availability for breeding birds.

During the literature search I searched on Google Scholar for each species in the Buceroti suborder and tried to find papers published which had numerical clutch size data. I also aimed to only use papers with data which is from later than 2000 to ensure the data is more recent and comparable between each species. There is, however, one species (Ceratogymna atrata) which I was unable to find a later dataset for on clutch size, so it is prior to 2000.

The clutch size data represents the mean number of eggs laid per breeding pair in a single brood for each species. I was unable to find Location data in the form of latitudinal and longitudinal co-ordinates, so the location data shown simply states the range of the species across the world.

Reference List:

Carstens, K.F., Kassanjee, R., Little, R.M., Ryan, P.G. and Hockey, P.A., 2019. The effects of weather, group size and type of nest on the timing of egg-laying in the Southern Ground-hornbill Bucorvus leadbeateri. Journal of Ornithology, 160, pp.633-640.

 Jetz, W., Sekercioglu, C.H. and Böhning-Gaese, K., 2008. The worldwide variation in avian clutch size across species and space. PLoS biology, 6(12), p.e303

 Phillimore, A.B., Freckleton, R.P., Orme, C.D.L. and Owens, I.P., 2006. Ecology predicts large-scale patterns of phylogenetic diversification in birds. The American Naturalist, 168(2), pp.220-229.

 Poulsen, H., 1970. Nesting Behaviour of the Black-Casqued Hornbill Ceratogymna atrata (Temm.) and the Great Hornbill Buceros bicornis L. Ornis Scandinavica, pp.11-15.

 Stander, M.C., Van de Ven, T.M. and Engelbrecht, D., 2004. Observations of nesting strategies of three African hornbill species.
DOI: 10.6084/m9.figshare.23803057
title: Additional file 3 of Novel covalent CDK7 inhibitor potently induces apoptosis in acute myeloid leukemia and synergizes with Venetoclax

description: Additional file 3: Supplementary Table 3.
DOI: 10.6084/m9.figshare.4928825
title: Efficient Sparse Estimate of Sufficient Dimension Reduction in High Dimension

description: In this article, we propose a new efficient sparse estimate (ESE) in sufficient dimension reduction using distance covariance. Our method is model-free and does not need any kernel function or slicing selection. Moreover, it can naturally deal with multivariate response scenarios, making it appealing in a modified sequential algorithm that targets the large <i>p</i> small <i>n</i> problems. Compared with screening procedures that only use marginal utility, our method can extract more useful information from the data and is capable of determining the size of the selected submodel automatically while most of screening procedures cannot. Under mild conditions, based on manifold theories and techniques, it can be shown that our method would perform asymptotically as well as if the true irrelevant predictors were known, which is referred to as the oracle property. Extensive simulation studies and two real data examples demonstrate the effectiveness and efficiency of the proposed approach. It is remarkable that the analysis in cardiomyopathy microarray data reveals distinct and interesting findings. Supplemental materials for this article are available online.
DOI: 10.6084/m9.figshare.19608940.v1
title: Hox transcript antisense RNA knockdown inhibits osteosarcoma progression by regulating the phosphoinositide 3-kinase/AKT pathway through the microRNA miR-6888-3p/spleen tyrosine kinase axis

description: Long non-coding RNA HOX transcript antisense RNA (lncRNA HOTAIR) is thought to be a key regulator of the occurrence and development of osteosarcoma (OS). The expression of HOTAIR, microRNA miR-6888-3p, spleen tyrosine kinase (SYK), and phosphoinositide 3-kinase/AKT (PI3K/AKT) pathway-related proteins in OS was detected by quantitative reverse transcription-PCR (qRT-PCR) and western blotting. Changes in the proliferation and migration of OS cells were detected by Cell Counting Kit-8 (CCK-8) and transwell assays after the knockdown of HOTAIR, miR-6888-3p, or SYK. Luciferase assays, RNA immunoprecipitation (RIP), and RNA pull-down assays were used to detect the relationship between miR-6888-3p and HOTAIR or SYK. We found that HOTAIR and SYK were highly expressed in OS, whereas miR-6888-3p expression was low. In addition, downregulation of HOTAIR or SYK significantly inhibited the growth and migration of OS cells and the PI3K/AKT pathway, both <i>in vitro</i> and <i>in vivo</i>. Additionally, downregulation of miR-6888-3p promoted the proliferation and migration of OS cells and activated the PI3K/AKT pathway. Mechanistically, these results suggest that the HOTAIR sponge, miR-6888-3p, regulates SYK expression. To summarize, HOTAIR regulates SYK by acting on miR-6888-3p, thereby promoting the proliferation and migration of OS cells.
DOI: 10.6084/m9.figshare.19608948
title: Long intergenic non-protein coding RNA 847 promotes laryngeal squamous cell carcinoma progression through the microRNA-181a-5p/zinc finger E-box binding homeobox 2 axis

description: The present study is targeted at investigating the effects of long intergenic non-protein coding RNA 847 (LINC00847) on the malignant biological behaviors of laryngeal squamous cell carcinoma (LSCC) cells, and the mechanisms. Quantitative real-time PCR and Western blotting were conducted for detecting the expressions of LINC00847, microRNA-181a-5p (miR-181a-5p) and zinc finger E-box binding homeobox 2 (ZEB2) in LSCC cell lines and tissue samples. BrdU, cell counting kit-8, scratch wound healing, Transwell and flow cytometry assays were utilized for detecting cell proliferation, migration, invasion, and cell cycle progression. Dual-luciferase reporter gene, RNA binding protein immunoprecipitation (RIP), and RNA pull-down assays were utilized to investigate the interaction among LINC00847, miR-181a-5p, and ZEB2. The subcellular location of LINC00847 was determined by RNA fluorescence in situ hybridization (RNA-FISH) assay. Tumor growth was evaluated using a xenograft model of nude mice. It was revealed that LINC00847 expression was increased in LSCC tissues, and its high expression was associated with lymph node metastasis and poor differentiation. LINC00847 was mainly located in the cytoplasm of LSCC cells, and LINC00847 overexpression promoted LSCC cell proliferation, migration, invasion, and accelerated the cell cycle progression while knocking down LINC00847 had the opposite effects <i>in vitro</i> and inhibited the tumor growth <i>in vivo</i>. LINC00847 directly targeted miR-181a-5p and negatively modulated miR-181a-5p expression. ZEB2 was a target gene of miR-181a-5p, and was positively and indirectly modulated by LINC00847. Our data suggest that LINC00847 promotes LSCC progression by regulating the miR-181a-5p/ZEB2 axis.
DOI: 10.6084/m9.figshare.19608948.v1
title: Long intergenic non-protein coding RNA 847 promotes laryngeal squamous cell carcinoma progression through the microRNA-181a-5p/zinc finger E-box binding homeobox 2 axis

description: The present study is targeted at investigating the effects of long intergenic non-protein coding RNA 847 (LINC00847) on the malignant biological behaviors of laryngeal squamous cell carcinoma (LSCC) cells, and the mechanisms. Quantitative real-time PCR and Western blotting were conducted for detecting the expressions of LINC00847, microRNA-181a-5p (miR-181a-5p) and zinc finger E-box binding homeobox 2 (ZEB2) in LSCC cell lines and tissue samples. BrdU, cell counting kit-8, scratch wound healing, Transwell and flow cytometry assays were utilized for detecting cell proliferation, migration, invasion, and cell cycle progression. Dual-luciferase reporter gene, RNA binding protein immunoprecipitation (RIP), and RNA pull-down assays were utilized to investigate the interaction among LINC00847, miR-181a-5p, and ZEB2. The subcellular location of LINC00847 was determined by RNA fluorescence in situ hybridization (RNA-FISH) assay. Tumor growth was evaluated using a xenograft model of nude mice. It was revealed that LINC00847 expression was increased in LSCC tissues, and its high expression was associated with lymph node metastasis and poor differentiation. LINC00847 was mainly located in the cytoplasm of LSCC cells, and LINC00847 overexpression promoted LSCC cell proliferation, migration, invasion, and accelerated the cell cycle progression while knocking down LINC00847 had the opposite effects <i>in vitro</i> and inhibited the tumor growth <i>in vivo</i>. LINC00847 directly targeted miR-181a-5p and negatively modulated miR-181a-5p expression. ZEB2 was a target gene of miR-181a-5p, and was positively and indirectly modulated by LINC00847. Our data suggest that LINC00847 promotes LSCC progression by regulating the miR-181a-5p/ZEB2 axis.
DOI: 10.6084/m9.figshare.19608936.v1
title: Plasmacytoma variant translocation 1 stabilized by EIF4A3 promoted malignant biological behaviors of lung adenocarcinoma by generating circular RNA LMNB2

description: Increasing evidence suggests that plasmacytoma variant translocation 1 (PVT1) plays a vital role in the development of multiple tumors including lung adenocarcinoma (LUAD). Eukaryotic initiation factor 4A-3 (EIF4A3) is considered a key factor in human cancers. However, the role and potential mechanism of PVT1 combined with EIF4A3 in LUAD remain unclear. This study investigated the effects and regulatory mechanisms of PVT1, EIF4A3, and circLMNB2 on the growth, migration, invasion, and epithelial-mesenchymal transition (EMT) of LUAD cells (H1299 and HCC827 cells) The expression level, diagnostic value and prognostic significance of PVT1, EIF4A3, and circLMNB2 were assessed, and enrichment analysis was performed using R package. Rescue experiments and a xenograft model were used to validate the PVT1/EIF4A3/circLMNB2 axis in LUAD. PVT1 and EIF4A3 were upregulated and indicated poor prognosis in LUAD. Knockdown of PVT1 and EIF4A3 suppressed LUAD cell proliferation, migration, invasion, and EMT. Mechanistically, PVT1 was stabilized by EIF4A3. PVT1 could recruit EIF4A3 to promote circLMNB2 expression. Rescue experiments indicated that circLMNB2 overexpression could reverse the reduced behavior caused by PVT1 or EIF4A3 knockdown. Enrichment analysis showed that PVT1/EIF4A3/circLMNB2 may regulate LUAD development by participating in ribosome biogenesis and spliceosome formation. Our findings demonstrate that PVT1/EIF4A3/circLMNB2 enhances the malignant behaviors of LUAD cells, providing a novel perspective for the clinical treatment of LUAD.
DOI: 10.6084/m9.figshare.12788901.v1
title: Additional file 1 of Identification of key genes in atrial fibrillation using bioinformatics analysis

description: Additional file 1: Table S1. The DEGs between AF and SR tissues.
DOI: 10.6084/m9.figshare.12788901
title: Additional file 1 of Identification of key genes in atrial fibrillation using bioinformatics analysis

description: Additional file 1: Table S1. The DEGs between AF and SR tissues.
DOI: 10.6084/m9.figshare.25213775
title: Amplex Red experiments elucidating XO and uricase activity on deaminated guanosine analogs

description: XO and Uricase have activity only when cypin deaminates the guanosine analogs first.
DOI: 10.6084/m9.figshare.25213775.v1
title: Amplex Red experiments elucidating XO and uricase activity on deaminated guanosine analogs

description: XO and Uricase have activity only when cypin deaminates the guanosine analogs first.
DOI: 10.6084/m9.figshare.23803231.v1
title: Additional file 3 of Changes in expression levels of erythrocyte and immune-related genes are associated with high altitude polycythemia

description: Supplementary Material 3
DOI: 10.6084/m9.figshare.23803234
title: Additional file 4 of Changes in expression levels of erythrocyte and immune-related genes are associated with high altitude polycythemia

description: Supplementary Material 4
DOI: 10.6084/m9.figshare.25213757
title: Global Aluminum GHG Emissions Inventory (CEADs-AGE)

description: This is the data file for review of the manuscript "Differentiated technology packages to deliver 1.5°C target for global aluminum smelters" submitted to Science. Four sheets are included, each representing the electricity-related CO2 emission, process-related CO2 emission, process-related PFCs emission, and total GHG emission of global aluminum smelters, all with unit million tons CO2e/year.
DOI: 10.6084/m9.figshare.25213757.v1
title: Global Aluminum GHG Emissions Inventory (CEADs-AGE)

description: This is the data file for review of the manuscript "Differentiated technology packages to deliver 1.5°C target for global aluminum smelters" submitted to Science. Four sheets are included, each representing the electricity-related CO2 emission, process-related CO2 emission, process-related PFCs emission, and total GHG emission of global aluminum smelters, all with unit million tons CO2e/year.
DOI: 10.6084/m9.figshare.23803234.v1
title: Additional file 4 of Changes in expression levels of erythrocyte and immune-related genes are associated with high altitude polycythemia

description: Supplementary Material 4
DOI: 10.6084/m9.figshare.23803225
title: Additional file 1 of Changes in expression levels of erythrocyte and immune-related genes are associated with high altitude polycythemia

description: Supplementary Material 1
DOI: 10.6084/m9.figshare.23803228
title: Additional file 2 of Changes in expression levels of erythrocyte and immune-related genes are associated with high altitude polycythemia

description: Supplementary Material 2
DOI: 10.6084/m9.figshare.23803087
title: Additional file 2 of A GATA2-CDC6 axis modulates androgen receptor blockade-induced senescence in prostate cancer

description: Additional file 2: Table S1. RNA sequencing raw data and analysis of enzalutamide-treated LNCaP cells versus untreated counterparts.
DOI: 10.6084/m9.figshare.23803087.v1
title: Additional file 2 of A GATA2-CDC6 axis modulates androgen receptor blockade-induced senescence in prostate cancer

description: Additional file 2: Table S1. RNA sequencing raw data and analysis of enzalutamide-treated LNCaP cells versus untreated counterparts.
DOI: 10.6084/m9.figshare.23803090.v1
title: Additional file 3 of A GATA2-CDC6 axis modulates androgen receptor blockade-induced senescence in prostate cancer

description: Additional file 3: Table S2. Pathway expression analysis of in vitro and in vivo enzalutamide-sensitive and –resistant prostate cancer samples. RNA sequencing data were retrieved from publically available datasets with accession numbers GSE55030, GSE109708, GSE184168, GSE163240, GSE150807 and GSE151083.
DOI: 10.25549/hhrohp-ouc113169865
title: Vuyiseka Dubula-Majola, interview, South Africa, 2022

description: Vuyiseka Dubula-Majola, South Africa, 2022 October 17, oral history interview by Asna Tabassum. The inteview was conducted over the Internet (Zoom) as part of the Health and Human Rights Oral History Project.Vuyiseka Dubula-Majola is the Director of the Africa Centre for HIV/AIDS Management at Stellenbosch University. A former secretary-general of the Treatment Action Campaign, she is also the founder of the Activist Centre for Education & Development and has spent her entire career on the frontline of the fight against HIV/AIDS, campaigning for better public policies for HIV treatment and the advancement of the rights of HIV positive people in South Africa. In 2018, Dubula-Majola was one of 15 recipients worldwide of the Franco-German Prize for Human Rights and the Rule of Law, awarded in recognition of her lifelong commitment to helping HIV positive people, especially women. In her oral history, she charts her involvement in HIV/AIDS activism, beginning with her own positive diagnosis in 2001. She shares how she became involved with the Treatment Action Campaign and the key milestones that have informed her work in the health and human rights space until present.
DOI: 10.25549/hhrohp-ouc1sto1803210
title: The Health and Human Rights Oral History Project
DOI: 10.25549/hhrohp-ouc1sto1803208
title: The Health and Human Rights Oral History Project
DOI: 10.25549/hhrohp-ouc113169439
title: Vuyiseka Dubula-Majola, interview, South Africa, 2022

description: Vuyiseka Dubula-Majola, South Africa, 2022 October 17, oral history interview by Asna Tabassum. The inteview was conducted over the Internet (Zoom) as part of the Health and Human Rights Oral History Project.Vuyiseka Dubula-Majola is the Director of the Africa Centre for HIV/AIDS Management at Stellenbosch University. A former secretary-general of the Treatment Action Campaign, she is also the founder of the Activist Centre for Education & Development and has spent her entire career on the frontline of the fight against HIV/AIDS, campaigning for better public policies for HIV treatment and the advancement of the rights of HIV positive people in South Africa. In 2018, Dubula-Majola was one of 15 recipients worldwide of the Franco-German Prize for Human Rights and the Rule of Law, awarded in recognition of her lifelong commitment to helping HIV positive people, especially women. In her oral history, she charts her involvement in HIV/AIDS activism, beginning with her own positive diagnosis in 2001. She shares how she became involved with the Treatment Action Campaign and the key milestones that have informed her work in the health and human rights space until present.
DOI: 10.25549/hhrohp-ouc113169308
title: Mandeep Dhaliwal, interview, New York, NY, USA, 2022

description: Mandeep Dhaliwal, New York, New York, USA, 2022 September 29, oral history interview by Lillie Guo, Los Angeles, California, USA. The inteview was conducted over the Internet (Zoom) as part of the Health and Human Rights Oral History Project.Dr. Mandeep Dhaliwal is the Director of the United Nations Development Program's HIV, Health and Development Group. A physician and lawyer, Dr. Dhaliwal has over 20 years of experience working on HIV, health, human rights and evidence-based policy and programming in low-and middle-income countries. She joined UNDP in 2008 as the Cluster Leader: Human Rights, Gender and Sexual Diversities in the HIV/AIDS Group. She was also the architect and lead for the Global Commission on HIV and the Law which UNDP convened on behalf of the Joint UN Program on HIV/AIDS. In her oral history, Dr. Dhaliwal discusses major inflection points in the global HIV response, beginning with her early interventions representing sex workers in India, to her work with the Lawyer’s Collective where she pioneered work on HIV and the law. Dr. Dhaliwal later went on to serve as a senior adviser to the Dutch Royal Tropical Institute’s Special Program on HIV/AIDS and as the lead on HIV care and treatment at the International HIV/AIDS Alliance. She shares critical reflections on centering the voices and experiences of those living with HIV, as well as community engagement and civil society activism.
DOI: 10.25549/hhrohp-ouc112603955
title: Lillie Guo, interview, Los Angeles, CA, USA, 2022

description: Lillie Guo, Los Angeles, California, USA, 2022 November 14, oral history interview, by Summer Peet, Los Angeles, California, USA. The inteview was conducted over the Internet (Zoom) as part of the Health and Human Rights Oral History Project.Lillie Guo is an undergraduate student at the University of Southern California (USC) Keck School of Medicine, studying Global Health with a minor in Spanish. She is also a Research Assistant with the USC Institute on Inequalities in Global Health and served as a student interviewer for the pilot phase of The Health and Human Rights Oral History Project (HHROHP). The following transcript reflects a conversation conducted near the conclusion of the pilot phase of the Project. Guo looks back on her participation in the HHROHP and shares the ways in which she approached the interviewer role, what she learned from the interviews she conducted, and in what ways the Project has impacted her.
DOI: 10.25549/hhrohp-ouc112603954
title: Maylis Basturk, interview, Los Angeles, CA, USA, 2022

description: Maylis Basturk, Los Angeles, California, USA, 2022 November 14, oral history interview, by Summer Peet, Los Angeles, California, USA. The inteview was conducted over the Internet (Zoom) as part of the Health and Human Rights Oral History Project.Maylis Basturk is a second year medical student at the University of Southern California Keck School of Medicine. She served as a student interviewer for the pilot phase of The Health and Human Rights Oral History Project (HHROHP). The following transcript reflects a conversation conducted near the conclusion of the pilot phase of the Project. Basturk looks back on her participation in the HHROHP and shares the ways in which she approached the interviewer role, what she learned from the interviews she conducted, and in what ways the Project has impacted her.