cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.26179/pft8-vc59
title: Australian Hydrographic Service Surveys at Davis Station - ITRF2000
DOI: 10.26179/r16w-am36
title: Amery Ice Shelf - hot water drill borehole AM06, RDI 300 kHz ADCP ocean velocity data 2010-2011
DOI: 10.26179/qk65-3g42
title: ASPeCt bridge-based sea-ice observations - 2007 to 2013
DOI: 10.26179/q9bd-5f74
title: Wave acquisition stereo-camera system measurements (WASS) from a voyage of the S.A. Agulhas II, July 2017
DOI: 10.26179/ppwg-5d78
title: Davis pyranometer and pyrgeometer data, 2018-2019
DOI: 10.5281/zenodo.7312611
title: Players' decisions data for exit-voice irrigation experiment

description: This data contains the decisions data of human-subject players who participated in the irrigation exit-voice experiment.
DOI: 10.5281/zenodo.7312610
title: Players' decisions data for exit-voice irrigation experiment

description: This data contains the decisions data of human-subject players who participated in the irrigation exit-voice experiment.
DOI: 10.6084/m9.figshare.21540072
title: fastq_baritula.tar

description: Diglossa baritula FASTQ files
DOI: 10.6084/m9.figshare.21540072.v1
title: fastq_baritula.tar

description: Diglossa baritula FASTQ files
DOI: 10.25442/hku.21400992
title: Supporting data for "Characterization of Chinese medicine celastrol and celastrol-loaded biodegradable nanoparticles towards the therapy of obesity and non-alcoholic fatty liver disease"

description: Obesity and non-alcoholic fatty liver disease (NAFLD) are hallmarked by aberrant lipid accumulation, persistent chronic inflammation and hyperactive endoplasmic reticulum (ER) stress. Warburg effect of aerobic glycolysis in hepatic M1 macrophages is a major cause for metabolic dysfunction and inflammatory stress NAFLD. Plant-derived triterpene celastrol markedly inhibited macrophage M1 polarization and adipocyte hypertrophy in obesity. The present study was designed to identify the celastrol-bound proteins which reprogrammed metabolic and inflammatory pathways in M1 macrophages. On the other hand, as a promising anti-obesity drug, plant-derived celastrol is challenged by poor water solubility and low oral bioavailability in clinical applications. The present study was designed to develop a biocompatible albumin-based nanoparticle carrier system for the controlled release of celastrol and targeted delivery in obesity and NAFLD mice. <br> The results demonstrated that celastrol might alleviate lipid accumulation, inflammation and fibrosis in the liver via covalent modification of PKM2. Meanwhile, the results indicated that albumin-based nanoparticles may be a general biocompatible drug carrier system for the controlled release of hydrophobic compounds (e.g., celastrol) for the treatment of obesity and NAFLD. This dataset contains the data from experimental results.
DOI: 10.25442/hku.21400992.v1
title: Supporting data for "Characterization of Chinese medicine celastrol and celastrol-loaded biodegradable nanoparticles towards the therapy of obesity and non-alcoholic fatty liver disease"

description: Obesity and non-alcoholic fatty liver disease (NAFLD) are hallmarked by aberrant lipid accumulation, persistent chronic inflammation and hyperactive endoplasmic reticulum (ER) stress. Warburg effect of aerobic glycolysis in hepatic M1 macrophages is a major cause for metabolic dysfunction and inflammatory stress NAFLD. Plant-derived triterpene celastrol markedly inhibited macrophage M1 polarization and adipocyte hypertrophy in obesity. The present study was designed to identify the celastrol-bound proteins which reprogrammed metabolic and inflammatory pathways in M1 macrophages. On the other hand, as a promising anti-obesity drug, plant-derived celastrol is challenged by poor water solubility and low oral bioavailability in clinical applications. The present study was designed to develop a biocompatible albumin-based nanoparticle carrier system for the controlled release of celastrol and targeted delivery in obesity and NAFLD mice. <br> The results demonstrated that celastrol might alleviate lipid accumulation, inflammation and fibrosis in the liver via covalent modification of PKM2. Meanwhile, the results indicated that albumin-based nanoparticles may be a general biocompatible drug carrier system for the controlled release of hydrophobic compounds (e.g., celastrol) for the treatment of obesity and NAFLD. This dataset contains the data from experimental results.
DOI: 10.25442/hku.21428049
title: Supporting data for Tectonics and River Processes: Three Case Studies in East Asia

description: This dataset contains OSL measurements used for the chapter two of the above titled thesis. The dataset are presented in four different folders. The READMe file provides information on the content of each of the files.
DOI: 10.25442/hku.21428049.v1
title: Supporting data for Tectonics and River Processes: Three Case Studies in East Asia

description: This dataset contains OSL measurements used for the chapter two of the above titled thesis. The dataset are presented in four different folders. The READMe file provides information on the content of each of the files.
DOI: 10.25919/nxp3-bw40
title: Parkes observations for project P971 semester 2022OCTS_01

description: We propose further timing observations of the relativistic pulsar - white-dwarf binary, PSR J1141$-$6545. This unique system offers access to a wide range of physics, from relativistic phenomena through pulsar emission cone studies, to the structure and distribution of interstellar plasma along our line-of-sight. The analysis of existing data has already revealed the first detection of Lense-Thirring precession in a binary star system, and hinted at complex emission beam structure probed via geodetic precession. Further timing of this system for the next few years is needed for studies of these effects at higher precision.
DOI: 10.25442/hku.21431073
title: Supporting data for "Age and vaccine-dependent anti-NA antibody response against A(H1N1) and A(H1N1)pdm09 influenza viruses".

description: There are 4 main datasets included 1. The NI titers measured for post-infection ferret anti-sera using Enzyme-Linked Lectin Assay (ELLA) to characterise the N1 NA antigenic drifts of A(H1N1) viruses between 1977-1991. 2. The HI and NI titers measured in individuals aged 5-70 years using HI assay and ELLA, respectively, to observe the immune imprinting patterns across a panel of antigenically distinct HA and NA proteins of A(H1N1) and A(H1N1)pdm09 viruses from 1977-2015. 3. The NI antibody titers measured using ELLA against antigenically distinct NAs from A(H1N1) and A(H1N1)pdm09 viruses from 1977-2009 in individuals who were infected with A(H1N1)pdm09 virus during 2013-2016 to observe the back-boosting of NI antibodies. 4. The NI titers measured using ELLA in individuals who recieved a single dose of SIIV and eIIV during 2017/2018 influenza season and NI titers in individuals who were repeatedly vaccinated for 2 influenza seasons (2017/2018, 2018/2019) using homologous and heterologous vaccines. Additionally, the NI titers measured using ELLA for a historical A(H1N1) strain in individuals who received a single dose of SIIV and eIIV during 2017/2018 influenza season to observe the back-boosting of NI antibodies with vaccination. <br>
DOI: 10.25442/hku.21431073.v1
title: Supporting data for "Age and vaccine-dependent anti-NA antibody response against A(H1N1) and A(H1N1)pdm09 influenza viruses".

description: There are 4 main datasets included 1. The NI titers measured for post-infection ferret anti-sera using Enzyme-Linked Lectin Assay (ELLA) to characterise the N1 NA antigenic drifts of A(H1N1) viruses between 1977-1991. 2. The HI and NI titers measured in individuals aged 5-70 years using HI assay and ELLA, respectively, to observe the immune imprinting patterns across a panel of antigenically distinct HA and NA proteins of A(H1N1) and A(H1N1)pdm09 viruses from 1977-2015. 3. The NI antibody titers measured using ELLA against antigenically distinct NAs from A(H1N1) and A(H1N1)pdm09 viruses from 1977-2009 in individuals who were infected with A(H1N1)pdm09 virus during 2013-2016 to observe the back-boosting of NI antibodies. 4. The NI titers measured using ELLA in individuals who recieved a single dose of SIIV and eIIV during 2017/2018 influenza season and NI titers in individuals who were repeatedly vaccinated for 2 influenza seasons (2017/2018, 2018/2019) using homologous and heterologous vaccines. Additionally, the NI titers measured using ELLA for a historical A(H1N1) strain in individuals who received a single dose of SIIV and eIIV during 2017/2018 influenza season to observe the back-boosting of NI antibodies with vaccination. <br>
DOI: 10.25442/hku.21427239
title: Supporting data for “IN-DEPTH STUDY OF ABERRANT CHROMATIN REGULATORS IN HEPATOCELLULAR CARCINOMA DEVELOPMENT”

description: Raw data for the research projects regarding the thesis “IN-DEPTH STUDY OF ABERRANT CHROMATIN REGULATORS IN HEPATOCELLULAR CARCINOMA DEVELOPMENT” for Ph.D. degree examination. <br> Three projects are included: <br> The first project investigated the oncogenic role of VPS72 in HCC which we previously reported it genetic amplification in liver cancer patients. In this thesis, we revealed an important master regulatory gene whos expression is repressed by excessive VPS72 and subsequently failed to maintain the metabolic balance in HCC cells. <br> The second project explored the previously reported protein-protein interaction of SIRT7 with NRF2 and how SIRT7 regulates the chronic activation of NRF2 signaling in HCC cells. <br> The third project is a side project conducted during the research to facilitate the design of molecular cloning. The McDesigner is a swift webserver able to provide various reliable molecular cloning strategies case by case.
DOI: 10.25442/hku.21427239.v1
title: Supporting data for “IN-DEPTH STUDY OF ABERRANT CHROMATIN REGULATORS IN HEPATOCELLULAR CARCINOMA DEVELOPMENT”

description: Raw data for the research projects regarding the thesis “IN-DEPTH STUDY OF ABERRANT CHROMATIN REGULATORS IN HEPATOCELLULAR CARCINOMA DEVELOPMENT” for Ph.D. degree examination. <br> Three projects are included: <br> The first project investigated the oncogenic role of VPS72 in HCC which we previously reported it genetic amplification in liver cancer patients. In this thesis, we revealed an important master regulatory gene whos expression is repressed by excessive VPS72 and subsequently failed to maintain the metabolic balance in HCC cells. <br> The second project explored the previously reported protein-protein interaction of SIRT7 with NRF2 and how SIRT7 regulates the chronic activation of NRF2 signaling in HCC cells. <br> The third project is a side project conducted during the research to facilitate the design of molecular cloning. The McDesigner is a swift webserver able to provide various reliable molecular cloning strategies case by case.
DOI: 10.6084/m9.figshare.21541509
title: supplementary_figs.zip

description: Image source files for “Fluorogenic reporter enables identification of compounds that inhibit SARS-CoV-2” supplementary figures.
DOI: 10.6084/m9.figshare.21541509.v1
title: supplementary_figs.zip

description: Image source files for “Fluorogenic reporter enables identification of compounds that inhibit SARS-CoV-2” supplementary figures.
DOI: 10.6084/m9.figshare.20103644
title: gamma_glu_leu_summary_statistics.txt

description: The data shows the summary statisitcss for genome-wide association study of Gamma-glutanyl-leucine.
DOI: 10.6084/m9.figshare.20103644.v1
title: gamma_glu_leu_summary_statistics.txt

description: The data shows the summary statisitcss for genome-wide association study of Gamma-glutanyl-leucine.
DOI: 10.6084/m9.figshare.21541491.v1
title: Evaluation of pharmacy access performance tables and figures.docx

description: This file is created for the study of the evaluation of pharmacy access performance (PAP). It includes the IVSFSs-based linguistic scale, the linguistic terms for fuzzy preferences of the best criterion, main criterion weights obtained with BBWM, treemap of the main criterion set, ranking of alternatives, PAP rankings in the districts of Antalya city.
DOI: 10.6084/m9.figshare.21541491
title: Evaluation of pharmacy access performance tables and figures

description: This file is created for the study of the evaluation of pharmacy access performance (PAP). It includes the IVSFSs-based linguistic scale, the linguistic terms for fuzzy preferences of the best criterion, main criterion weights obtained with BBWM, treemap of the main criterion set, ranking of alternatives, PAP rankings in the districts of Antalya city.
DOI: 10.6084/m9.figshare.21541491.v3
title: Evaluation of pharmacy access performance tables and figures

description: This file is created for the study of the evaluation of pharmacy access performance (PAP). It includes the IVSFSs-based linguistic scale, the linguistic terms for fuzzy preferences of the best criterion, main criterion weights obtained with BBWM, treemap of the main criterion set, ranking of alternatives, PAP rankings in the districts of Antalya city.
DOI: 10.6084/m9.figshare.21541491.v2
title: Evaluation of pharmacy access performance tables and figures.docx

description: This file is created for the study of the evaluation of pharmacy access performance (PAP). It includes the IVSFSs-based linguistic scale, the linguistic terms for fuzzy preferences of the best criterion, main criterion weights obtained with BBWM, treemap of the main criterion set, ranking of alternatives, PAP rankings in the districts of Antalya city.
DOI: 10.26188/20224374
title: REMOVED

description: This dataset contains the results of the agent miner algorithm evaluation on 10 real-world BPIC event sets and 6 synthetic event sets. <br> Applied configuration: max_dfg_dist (synthetic) = 0.5 (v10) max_dfg_dist (bpic) = 0.25 (v09) requested_agent_count = 7 (v09 and v10) requested activity type per agent = 7 (v09 and v10) <br>
DOI: 10.26188/20224374.v3
title: REMOVED

description: This dataset contains the results of the agent miner algorithm evaluation on 10 real-world BPIC event sets and 6 synthetic event sets. <br> Applied configuration: max_dfg_dist (synthetic) = 0.5 (v10) max_dfg_dist (bpic) = 0.25 (v09) requested_agent_count = 7 (v09 and v10) requested activity type per agent = 7 (v09 and v10) <br>
DOI: 10.13012/b2idb-4432073_v1
title: Data for Chemical Short-Range Ordering in a CrCoNi Medium-Entropy Alloy

description: This dataset is for characterizing chemical short-range-ordering in CrCoNi medium entropy alloys. It has three sub-folders: 1. code, 2. sample WQ, 3. sample HT. The software needed to run the files is Gatan Microscopy Suite® (GMS). Please follow the instruction on this page to install the DM3 GMS: https://www.gatan.com/installation-instructions#Step1 1. Code folder contains three DM scripts to be installed in Gatan DigitalMicrograph software to analyze scanning electron nanobeam diffraction (SEND) dataset: Cepstrum.s: need [EF-SEND_sampleWQ_cropped_aligned.dm3] in Sample WQ and the average image from [EF-SEND_sampleWQ_cropped_aligned.dm3]. Same for Sample HT folder. log_BraggRemoval.s: same as above. Patterson.s: Need refined diffuse patterns in Sample HT folder. 2. Sample WQ and 3. Sample HT folders both contain the SEND data (.ser) and the binned SEND data (.dm3) as well as our calculated strain maps as the strain measurement reference. The Sample WQ folder additionally has atomic resolution STEM images; the Sample HT folder additionally has three refined diffuse patterns as references for diffraction data processing. * Only .ser file is needed to perform the strain measurement using imToolBox as listed in the manuscript. .emi file contains the meta data of the microscope, which can be opened together with .ser file using FEI TIA software.
DOI: 10.26188/20224374.v2
title: Agent Miner : evaluation results

description: This dataset contains the results of the agent miner algorithm evaluation on 10 real-world BPIC event sets and 6 synthetic event sets. <br> Applied configuration: max_dfg_dist (synthetic) = 0.5 (v10) max_dfg_dist (bpic) = 0.25 (v09) requested_agent_count = 7 (v09 and v10) requested activity type per agent = 7 (v09 and v10) <br>
DOI: 10.15151/esrf-es-924501946
title: BAG Barcelona

description: BAG Barcelona has a long tradition of accessing the ESRF. It is constituted by 10 groups that belong to the Institute of Molecular Biology Barcelona from the Spanish Research Council (IBMB-CSIC), the Institute for Research in Biomedicine (IRB), and the Research Institute from Hospital Santa Creu i Sant Pau (HSCSP-IR). The main subjects of research are protein/DBA complexes, molecular machines, compounds of viruses, molecular mechanisms of proteases, and other enzymes. Recently, a new group (E. Marcos) interested in de-novo designed protein scaffolds has joined the BAG. Our Scientific results strongly rely on the high-quality data and excellent performance and support of ESRF macromolecular crystallography beamlines.
DOI: 10.15151/esrf-es-925342731
title: PROTEINS RELATED TO PATHOGENESIS OF DISEASES, VIRAL PROTEINS, CELL DIVISION, SIGNALLING AND CHROMATIN PROCESSES

description: Our BAG is composed of eight PIs at six different institutions in Italy and Austria. We focus on a large variety of human, bacterial, viral and synthetic protein targets and address diverse biological contexts by combining structural biology with biochemistry, biophysics, cellular and in vivo investigations.
DOI: 10.15151/esrf-es-925344270
title: ITABAG: 3D structures of macromolecules related to human health

description: The ITABAG includes structural biologists from Universities, the National Research Council and Hospital research centres in Italy. The laboratories take advantage of single crystal and small angle X-ray diffraction methods to study the structure-function relationships in various macromolecules. A unifying factor for the vast majority of the macromolecules under study is that they are related to human health, either directly, being human proteins involved in some disease, or indirectly, as proteins expressed by human pathogens and validated as potential pharmacological targets. Other projects investigate basic chemical processes, such as crystal growth, or aim at characterising macromolecules with potential biotechnological applications.
DOI: 10.15151/esrf-es-928405015
title: Berlin-Karlsruhe - Macromolecular Crystallography BAG - Structural Biology of light responsive, signal transducing and metalloproteins

description: The project aims to investigate structure-function relationships in different groups of soluble and membrane proteins, most of which are involved in signal transduction or energy conversion. We investigate the signalling mechanisms of phytochromes by focusing on the structures of the intermediates of the photocycle and by analysing domain movements or by introducing unnatural amino acids. We analyse the structures of different G protein-coupled receptors (GPCRs; e.g. melanocortin-4 receptor and rhodopsin), either alone or in complex with their cognate G-proteins, to understand their signalling mechanisms. In our work on the biocatalytic splitting of molecular hydrogen into protons and electrons, we analyse the membrane-bound and soluble [NiFe] hydrogenases, proteins of the remarkably small subgroup of hydrogenases that are active under aerobic conditions. Other research areas include mechanosensitive channels, microbial rhodopsins, cytomegalovirus proteins and DNA photolyases.
DOI: 10.15151/esrf-es-945455503
title: Role of stretch-induced structural changes in the myofilaments in the length-dependent activation of cardiac muscle

description: A healthy heart produces a stronger contraction in response to increased venous filling, a response known as the Frank-Starling relationship. Despite decades of investigation at the cellular level, the molecular basis of this so-called “length-dependent activation” (LDA) in cardiac muscle is still unclear. Here we will use a combination of mechanical protocols and small-angle X-ray diffraction at ID02 on electrically paced muscle tissue isolated from the rat heart to determine the dynamic structural changes in the constituent myosin and actin filaments induced by an increase in muscle length during the relaxed phase of the cardiac cycle. Disruption of LDA is a common pathogenic mechanism underlying cardiac dysfunction: the results of this research will provide new targets and assays for the development of new pharmacological approaches to treat heart failure in cardiac diseases.
DOI: 10.15151/esrf-es-945456988
title: Single crystal structural studies of alkali carbonates Na2CO3, K2CO3 and NaKCO3 at high pressures and temperatures

description: This proposal aims to study the Na2CO3 - K2CO3 system from a structural point of view using single crystal diffraction at simultaneous high pressure and temperature in the range 0-15 GPa and 0-1200 K with resistive heated DACs. The experiments are aimed both at the structural determination of alkaline carbonates at variable pressures and temperatures, and at the determination of accurate thermal EoS for the different polymorphs.
DOI: 10.15470/xpzkxb
title: Lista nacional (National Checklist) de Myxomycetes (Ceratiomyxales, Echinosteliales, Liceales y Trichiales) de la Pen?nsula Ib?rica

description: This dataset contains 127 taxa corresponding to species of Mycetozoa included in the orders Ceratiomyxales, Echinosteliales, Liceales and Trichiales present in the Iberian Peninsula. It is based on the taxonomic and chorological work carried out within the Flora Mycologica Iberica project, which results for this groups were published in : Lado, C. & Pando, F. 1997. Flora Mycologica Iberica, Vol. 2. Myxomycetes, I. Ceratiomyxales, Echinosteliales, Liceales, Trichiales. - Real Jardin Bot?nico Madrid, Consejo Superior de Investigaciones Cient?ficas. J. Kramer, Madrid, Berlin, Stuttgart This dataset was prepared as one of the deliverables of the GBIF's CESP 20'18 project "Increasing capacities to develop National Species Checklists in the Latin America and the Caribbean Region", to test the set of good practices compiled within the project.
DOI: 10.48668/v6g4jm/yunix5
title: FIGURE 1_for repository_family based int_07Jan2022.pptx

description: Figure 1: The CONSORT diagram
DOI: 10.48668/v6g4jm/sn4nnk
title: TABLE 2_for repository_family based int_07Jan2022.docx

description: Table 2: Baseline characteristics of the younger family members among the dyads (N=256)
DOI: 10.48668/v6g4jm/azl3fo
title: TABLE 4_for repository_family based int_07Jan2022.docx

description: Table 4: The results of the satisfaction survey among the dyads in the intervention group
DOI: 10.48668/v6g4jm/8olkhw
title: TABLE 3_for repository_family based int_07Jan2022.docx

description: Table 3: Between-group comparisons of outcomes among the dyad participants
DOI: 10.48668/v6g4jm/6kwgne
title: TABLE 1_for repository_family based int_07Jan2022.docx

description: Table 1: Baseline characteristics of the older adults among the dyads (N=320)
DOI: 10.48668/v6g4jm
title: Effect of a family-based multimedia intervention on the uptake of faecal immunohistochemical test among South Asian older adults: A cluster-randomised controlled trial

description: Data for the assessment of the feasibility, acceptability and effectiveness of a family-based multimedia intervention to enhance faecal immunohistochemical test utilisation among South Asian older adults in Hong Kong