cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.3187897.v1
title: Molecular Dynamics Study of the Membrane Interaction of a Membranotropic Dengue Virus C Protein Derived Peptide

description: Dengue virus C protein, essential in the Dengue virus life cycle, possess a segment, peptide PepC, known to bind membranes composed of negatively-charged phospholipids. To characterize its interaction with the membrane we have used the molecular dynamics HMMM membrane model system. This approach is able of achieving a stable system and sampling the peptide/lipid interactions which determine the orientation and insertion of the peptide upon membrane binding. We have been able of demonstrating spontaneous binding of PepC to the 1,2-Divaleryl-sn-glycero-3-phosphate / 1,2-Divaleryl-sn-glycero-3-phosphocholine membrane model system whereas no binding was observed at all for the 1,2-Divaleryl-sn-glycero-3-phosphocholine one. PepC, adopting an α-helix profile, did not insert into the membrane but did bind to its surface through a charge anchor formed by its three positively-charged residues. PepC, maintaining its three dimensional structure along the whole simulation, presented a nearly parallel orientation with respect to the membrane when bound to it. The positively-charged amino acids residues Arg-2, Lys-6 and Arg-16 are the main responsible for the peptide binding to the membrane stabilizing the structure of the bound peptide. The segment of Dengue virus C protein where PepC resides is a fundamental protein-membrane interface which might control protein/membrane interaction, and its positive amino acids are responsible for membrane binding defining its specific location in the bound state. These data should help in our understanding of the molecular mechanism of DENV life cycle as well as making possible the future development of potent inhibitor molecules, which target Dengue virus C protein structures involved in membrane binding.
DOI: 10.6084/m9.figshare.3188002.v2
title: Freddie Mercury—acoustic analysis of speaking fundamental frequency, vibrato, and subharmonics

description: Freddie Mercury was one of the twentieth century’s best-known singers of commercial contemporary music. This study presents an acoustical analysis of his voice production and singing style, based on perceptual and quantitative analysis of publicly available sound recordings. Analysis of six interviews revealed a median speaking fundamental frequency of 117.3 Hz, which is typically found for a baritone voice. Analysis of voice tracks isolated from full band recordings suggested that the singing voice range was 37 semitones within the pitch range of F#2 (about 92.2 Hz) to G5 (about 784 Hz). Evidence for higher phonations up to a fundamental frequency of 1,347 Hz was not deemed reliable. Analysis of 240 sustained notes from 21 a-cappella recordings revealed a surprisingly high mean fundamental frequency modulation rate (vibrato) of 7.0 Hz, reaching the range of vocal tremor. Quantitative analysis utilizing a newly introduced parameter to assess the regularity of vocal vibrato corroborated its perceptually irregular nature, suggesting that vibrato (ir)regularity is a distinctive feature of the singing voice. Imitation of subharmonic phonation samples by a professional rock singer, documented by endoscopic high-speed video at 4,132 frames per second, revealed a 3:1 frequency locked vibratory pattern of vocal folds and ventricular folds.
DOI: 10.6084/m9.figshare.3187828
title: <i>LINE-1</i> and inflammatory gene methylation levels are early biomarkers of metabolic changes: association with adiposity

description: We analyzed whether global and inflammatory genes methylation can be early predictors of metabolic changes and their associations with the diet, in a cross-sectional study (<i>n</i> = 40). Higher global methylation was associated to adiposity, insulin resistance, and lower quality of the diet. Methylation of <i>IL-6, SERPINE1</i> and <i>CRP</i> genes was related to adiposity traits and macronutrients intake. <i>SERPINE1</i> hypermethylation was also related to some metabolic alterations. <i>CRP</i> methylation was a better predictor of insulin resistance than CRP plasma concentrations. Global and inflammatory gene promoter hypermethylation can be good early biomarkers of adiposity and metabolic changes and are associated to the quality of the diet.
DOI: 10.6084/m9.figshare.3187876
title: pan_genome_sequences.zip

description: sdadadaa
DOI: 10.6084/m9.figshare.3187903.v3
title: FOOD resources: ontologies and data

description: This dataset contains all the excel files, the ontologies (accompanied by their HTML documentation and diagrams) and data developed in the context of the Italian project "FOOD: Food in Open Data".<br>
DOI: 10.6084/m9.figshare.3187840
title: Recent independent emergence of multiple multi-drug resistant Serratia marcescens clones within the United Kingdom and Ireland

description: The folder contain multi-fasta files for the genes in the pan-genome of multiple multi-drug resistant Serratia marcescens <br>
DOI: 10.6084/m9.figshare.3187876.v1
title: pan_genome_sequences.zip

description: sdadadaa
DOI: 10.6084/m9.figshare.3187756
title: Supplementary file.xlsx

description: The concentrations of Cu, Ni, Pb, Zn, Cd, and Cr were analyzed from 87 topsoil samples in the pre-rainy season and 115 samples in the post-rainy season. The Cd concentration was determined through inductively coupled plasma mass spectrometry (ICP-MS, Baird ICP2070, USA). The concentrations of Cu, Ni, Pb, Zn, and Cr were determined using an inductively coupled plasma optical emission spectrometer (ICP-OES, Baird ICP2070, USA). The pollution index (PI) of heavy metals was calculated from the measured and background concentrations. The ecological risk index (RI) was assessed based on the PI values and toxic-response parameters.
DOI: 10.6084/m9.figshare.3187828.v1
title: <i>LINE-1</i> and inflammatory gene methylation levels are early biomarkers of metabolic changes: association with adiposity

description: We analyzed whether global and inflammatory genes methylation can be early predictors of metabolic changes and their associations with the diet, in a cross-sectional study (<i>n</i> = 40). Higher global methylation was associated to adiposity, insulin resistance, and lower quality of the diet. Methylation of <i>IL-6, SERPINE1</i> and <i>CRP</i> genes was related to adiposity traits and macronutrients intake. <i>SERPINE1</i> hypermethylation was also related to some metabolic alterations. <i>CRP</i> methylation was a better predictor of insulin resistance than CRP plasma concentrations. Global and inflammatory gene promoter hypermethylation can be good early biomarkers of adiposity and metabolic changes and are associated to the quality of the diet.
DOI: 10.6084/m9.figshare.3187903.v4
title: FOOD resources: ontologies and data

description: This dataset is the outcome of an e-government project named FOOD, FOod in Open Data, which was carried out in the context of a collaboration between the Institute of Cognitive Sciences and Technologies of the Italian National Research Council, the Italian Ministry of Agriculture (MIPAAF) and the Italian Digital Agency (AgID). In particular, we implemented several ontologies for describing protected names of products (wine, pasta, fish, oil, etc.). In addition, we present the process carried out for producing and publishing a LOD dataset containing data extracted from existing Italian policy documents on such products and compliant with the aforementioned ontologies.<br><br>This dataset contains all the excel files, the ontologies, accompanied by their HTML documentation (in English and Italian) and diagrams, and data developed in the context of the Italian project "FOOD: Food in Open Data".<br>
DOI: 10.6084/m9.figshare.3187756.v2
title: Supplementary file.xlsx

description: The concentrations of Cu, Ni, Pb, Zn, Cd, and Cr were analyzed from 87 topsoil samples in the pre-rainy season and 115 samples in the post-rainy season. The Cd concentration was determined through inductively coupled plasma mass spectrometry (ICP-MS, Baird ICP2070, USA). The concentrations of Cu, Ni, Pb, Zn, and Cr were determined using an inductively coupled plasma optical emission spectrometer (ICP-OES, Baird ICP2070, USA). The pollution index (PI) of heavy metals was calculated from the measured and background concentrations. The ecological risk index (RI) was assessed based on the PI values and toxic-response parameters.
DOI: 10.6084/m9.figshare.3187756.v1
title: Supplementary file.xlsx

description: The concentrations of Cu, Ni, Pb, Zn, Cd, and Cr were analyzed from 87 topsoil samples in the pre-rainy season and 115 samples in the post-rainy season. The Cd concentration was determined through inductively coupled plasma mass spectrometry (ICP-MS, Baird ICP2070, USA). The concentrations of Cu, Ni, Pb, Zn, and Cr were determined using an inductively coupled plasma optical emission spectrometer (ICP-OES, Baird ICP2070, USA). The pollution index (PI) of heavy metals was calculated from the measured and background concentrations. The ecological risk index (RI) was assessed based on the PI values and toxic-response parameters.
DOI: 10.6084/m9.figshare.3187840.v1
title: Recent independent emergence of multiple multi-drug resistant Serratia marcescens clones within the United Kingdom and Ireland

description: The folder contain multi-fasta files for the genes in the pan-genome of multiple multi-drug resistant Serratia marcescens <br>
DOI: 10.6084/m9.figshare.3187713
title: PRE data for "Structure Ensemble of the First Two RNA Recognition Motif Domains of a Poly(U) Binding Protein from Paramagnetic Relaxation Enhancement and Molecular Simulation"

description: <br> <b>Structure Ensemble of the First Two </b><b>RNA Recognition Motif</b><b> Domains of a Poly(U) Binding Protein from Paramagnetic Relaxation Enhancement and Molecular Simulation</b> <b> </b> Guanhua Zhu<sup>1</sup>, Wei Liu<sup>2</sup>, Chenglong Bao<sup>3</sup>, Dudu Tong<sup>1</sup>, Hui Ji<sup>3</sup>, Zuowei Shen<sup>3</sup>, Daiwen Yang<sup>2</sup>, Lanyuan Lu<sup>1*</sup><sup>Manuscript submitted for review.</sup>
DOI: 10.6084/m9.figshare.3187709
title: Effect of some managerial factors on behavior and performance of quail.pdf

description: Our work was carried out in three separate experiments; The first experiment concluded that cage systems are still the most efficient form of housing for breeder Japanese quail because it was accompanied with greatest feeding and drinking, egg production, hatchability,egg quality and lower mortality percent, but in order to reduce the welfare problems associated with these systems, the birds have to be equipped at minimum with an area for pecking, scratching, and dust-bathing to meet the fundamental behavioral needs of birds. The second experiment summarized that the sex ratio 1 male to 3 females was the optimum mating ratio in mass-mated groups of Japanese quail which lead to highest level of complete mating, egg production, maximum fertility and hatchability, and lowest level of agonistic encounters. The third experiment revealed that the puberty and sexual maturity ages of female quail were found to be 48 and 54 days, respectively. While in male quail they were found to be 32 and 42 days, respectively. The meat of Japanese quail (breast meat) contains 74.58% moisture, 18.88% protein, 3.45% fat and 2.57% ash in female, while in males 73.90% moisture, 19.75% protein, 2.58% fat.
DOI: 10.6084/m9.figshare.3187709.v1
title: Effect of some managerial factors on behavior and performance of quail.pdf

description: Our work was carried out in three separate experiments; The first experiment concluded that cage systems are still the most efficient form of housing for breeder Japanese quail because it was accompanied with greatest feeding and drinking, egg production, hatchability,egg quality and lower mortality percent, but in order to reduce the welfare problems associated with these systems, the birds have to be equipped at minimum with an area for pecking, scratching, and dust-bathing to meet the fundamental behavioral needs of birds. The second experiment summarized that the sex ratio 1 male to 3 females was the optimum mating ratio in mass-mated groups of Japanese quail which lead to highest level of complete mating, egg production, maximum fertility and hatchability, and lowest level of agonistic encounters. The third experiment revealed that the puberty and sexual maturity ages of female quail were found to be 48 and 54 days, respectively. While in male quail they were found to be 32 and 42 days, respectively. The meat of Japanese quail (breast meat) contains 74.58% moisture, 18.88% protein, 3.45% fat and 2.57% ash in female, while in males 73.90% moisture, 19.75% protein, 2.58% fat.
DOI: 10.6084/m9.figshare.3187703
title: Kruppel-like factor 4 (KLF-4) inhibits the epithelial-to-mesenchymal transition and proliferation of human endometrial carcinoma cells

description: Kruppel-like factors (KLFs) are a group of transcriptional regulators, being tumor-suppressive in various types of cancers, but not clear in human endometrial carcinoma (EC). We investigated the KLF-4 expression in both mRNA and protein levels in 29 EC specimens with RT-qPCR and Western blotting methods, and then to determine its promotion to Epithelial-to-mesenchymal transition (EMT) and proliferation of EC Ishikawa cells, via analyzing EMT-associated markers and via CCK-8 and colony forming assay. We found the downregulation of KLF-4 in the 29 EC specimens, correlating with the EC malignance. Moreover, we confirmed reduced levels of EMT and cell proliferation of Ishikawa cells post-KLF-4 overexpression. In conclusion, the significantly reduced KLF-4 correlated with the EC malignance. And the overexpressed KLF-4 promoted the EMT and proliferation of EC cells <i>in vitro</i>. The present study recognized the tumor suppressive role of KLF-4 in EC.
DOI: 10.6084/m9.figshare.3187840.v2
title: Recent independent emergence of multiple multi-drug resistant Serratia marcescens clones within the United Kingdom and Ireland

description: The folder contain multi-fasta files for the genes in the pan-genome of multiple multi-drug resistant Serratia marcescens <br>
DOI: 10.6084/m9.figshare.3187705
title: Pub1-PRE experimental data.zip

description: Exp. PRE data<br>
DOI: 10.6084/m9.figshare.3187840.v4
title: Recent independent emergence of multiple multi-drug resistant Serratia marcescens clones within the United Kingdom and Ireland

description: The folder contain multi-fasta files for the genes in the pan-genome of multiple multi-drug resistant Serratia marcescens <br>
DOI: 10.6084/m9.figshare.3187713.v2
title: PRE data for "Structure Ensemble of the First Two RNA Recognition Motif Domains of a Poly(U) Binding Protein from Paramagnetic Relaxation Enhancement and Molecular Simulation"

description: <br> <b>Structure Ensemble of the First Two </b><b>RNA Recognition Motif</b><b> Domains of a Poly(U) Binding Protein from Paramagnetic Relaxation Enhancement and Molecular Simulation</b> <b> </b> Guanhua Zhu<sup>1</sup>, Wei Liu<sup>2</sup>, Chenglong Bao<sup>3</sup>, Dudu Tong<sup>1</sup>, Hui Ji<sup>3</sup>, Zuowei Shen<sup>3</sup>, Daiwen Yang<sup>2</sup>, Lanyuan Lu<sup>1*</sup><sup>Manuscript submitted for review.</sup>
DOI: 10.6084/m9.figshare.3187703.v1
title: Kruppel-like factor 4 (KLF-4) inhibits the epithelial-to-mesenchymal transition and proliferation of human endometrial carcinoma cells

description: Kruppel-like factors (KLFs) are a group of transcriptional regulators, being tumor-suppressive in various types of cancers, but not clear in human endometrial carcinoma (EC). We investigated the KLF-4 expression in both mRNA and protein levels in 29 EC specimens with RT-qPCR and Western blotting methods, and then to determine its promotion to Epithelial-to-mesenchymal transition (EMT) and proliferation of EC Ishikawa cells, via analyzing EMT-associated markers and via CCK-8 and colony forming assay. We found the downregulation of KLF-4 in the 29 EC specimens, correlating with the EC malignance. Moreover, we confirmed reduced levels of EMT and cell proliferation of Ishikawa cells post-KLF-4 overexpression. In conclusion, the significantly reduced KLF-4 correlated with the EC malignance. And the overexpressed KLF-4 promoted the EMT and proliferation of EC cells <i>in vitro</i>. The present study recognized the tumor suppressive role of KLF-4 in EC.
DOI: 10.6084/m9.figshare.3187840.v3
title: Recent independent emergence of multiple multi-drug resistant Serratia marcescens clones within the United Kingdom and Ireland

description: The folder contain multi-fasta files for the genes in the pan-genome of multiple multi-drug resistant Serratia marcescens <br>
DOI: 10.6084/m9.figshare.3187693
title: Using the modified Delphi method to establish clinical consensus for the diagnosis and treatment of patients with rotator cuff pathology (Round 1 and 2 Data Sets)

description: A modified Delphi method was used to establish clinical practice guidelines for the treatment and management of patients with rotator cuff pathology. This are the results from Round 1 and 2 voting.
DOI: 10.6084/m9.figshare.3187705.v1
title: Pub1-PRE experimental data.zip

description: Exp. PRE data<br>
DOI: 10.6084/m9.figshare.3187713.v1
title: Pub1-PRE experimental data.zip

description: <br> <b>Structure Ensemble of the First Two </b><b>RNA Recognition Motif</b><b> Domains of a Poly(U) Binding Protein from Paramagnetic Relaxation Enhancement and Molecular Simulation</b> <b> </b> Guanhua Zhu<sup>1</sup>, Wei Liu<sup>2</sup>, Chenglong Bao<sup>3</sup>, Dudu Tong<sup>1</sup>, Hui Ji<sup>3</sup>, Zuowei Shen<sup>3</sup>, Daiwen Yang<sup>2</sup>, Lanyuan Lu<sup>1*</sup><sup>Manuscript submitted for review.</sup>
DOI: 10.6084/m9.figshare.3187693.v1
title: Using the modified Delphi method to establish clinical consensus for the diagnosis and treatment of patients with rotator cuff pathology (Round 1 and 2 Data Sets)

description: A modified Delphi method was used to establish clinical practice guidelines for the treatment and management of patients with rotator cuff pathology. This are the results from Round 1 and 2 voting.
DOI: 10.6084/m9.figshare.3187683
title: 2014 07 22 VID00001 Enhanced Frames

description: Segment of frames of VID00001 taken on 22 July 2014. Frames bracket the best single frame at VID00001 0 20 28-60. Frames are extracted using Cisco FlipShare software distributed with the Cisco Flip UltraHD 720p digital video recorder used to record the video. Frames are then enhanced using Adobe Photoshop Creative Cloud as follows:1) Image Size; Width 300%; Resolution: 300 per inch; With Scale Styles; With Constrain Proportions; Interpolation: preserve details; Noise: 100.2) Save; As: PNG Format; Interlace: None; Filter: Adaptive; Compression: 9.<br><br>Project order 33a<br>
DOI: 10.6084/m9.figshare.3187685
title: 2014 07 22 VID00001 Enhanced Frames No Denoise

description: Segment of frames of VID00001 taken on 22 July 2014. Frames bracket the best single frame at VID00001 0 20 28-60. Frames are extracted using Cisco FlipShare software distributed with the Cisco Flip UltraHD 720p digital video recorder used to record the video. Frames are then enhanced using Adobe Photoshop Creative Cloud as follows:1) Image Size; Width 300%; Resolution: 300 per inch; With Scale Styles; With Constrain Proportions; Interpolation: preserve details; Noise: 0.2) Save; As: PNG Format; Interlace: None; Filter: Adaptive; Compression: 9.These settings best preserve fine details through the enlargement process.<br><br>Project order 34a<b></b><i></i><sub></sub><sup></sup><br><br>
DOI: 10.6084/m9.figshare.3187683.v2
title: 2014 07 22 VID00001 Enhanced Frames

description: Segment of frames of VID00001 taken on 22 July 2014. Frames bracket the best single frame at VID00001 0 20 28-60. Frames are extracted using Cisco FlipShare software distributed with the Cisco Flip UltraHD 720p digital video recorder used to record the video. Frames are then enhanced using Adobe Photoshop Creative Cloud as follows:1) Image Size; Width 300%; Resolution: 300 per inch; With Scale Styles; With Constrain Proportions; Interpolation: preserve details; Noise: 100.2) Save; As: PNG Format; Interlace: None; Filter: Adaptive; Compression: 9.<br><br>Project order 33a<br>
DOI: 10.6084/m9.figshare.3187689.v1
title: Round 1 Results.pdf

description: Dephi Methodology used in Consensus Statement Development for clinical practice guidelines in the management and treatment of rotator cuff disorders.
DOI: 10.6084/m9.figshare.3187683.v1
title: 22 July 2014 VID00001 Enhanced Frames

description: Segment of frames of VID00001 taken on 22 July 2014. Frames bracket the best single frame at VID00001 0 20 28-60. Frames are extracted using Cisco FlipShare software distributed with the Cisco Flip UltraHD 720p digital video recorder used to record the video. Frames are then enhanced using Adobe Photoshop Creative Cloud as follows:1) Image Size; Width 300%; Resolution: 300 per inch; With Scale Styles; With Constrain Proportions; Interpolation: preserve details; Noise: 100.2) Save; As: PNG Format; Interlace: None; Filter: Adaptive; Compression: 9.<br>
DOI: 10.6084/m9.figshare.3187669
title: The noise pareidolia test

description: A simple neuropsychological test evoking and measuring visual hallucination-like illusions in dementia with Lewy body and other dementia disorders.
DOI: 10.6084/m9.figshare.3187685.v1
title: 22 July 2014 Enhanced Frames No Denoise

description: Segment of frames of VID00001 taken on 22 July 2014. Frames bracket the best single frame at VID00001 0 20 28-60. Frames are extracted using Cisco FlipShare software distributed with the Cisco Flip UltraHD 720p digital video recorder used to record the video. Frames are then enhanced using Adobe Photoshop Creative Cloud as follows:1) Image Size; Width 300%; Resolution: 300 per inch; With Scale Styles; With Constrain Proportions; Interpolation: preserve details; Noise: 0.2) Save; As: PNG Format; Interlace: None; Filter: Adaptive; Compression: 9.These settings best preserve fine details through the enlargement process.<b></b><i></i><sub></sub><sup></sup><br><br>
DOI: 10.6084/m9.figshare.3187655
title: 2014 09 20 VID00043 Enhanced Frames No Denoise

description: Every frame of VID00043 taken on 20 September 2014. Frames are extracted using Cisco FlipShare software distributed with the Cisco Flip UltraHD 720p digital video recorder used to record the video. Frames are then enhanced using Adobe Photoshop Creative Cloud as follows:1) Image Size; Width 300%; Resolution: 300 per inch; With Scale Styles; With Constrain Proportions; Interpolation: preserve details; Noise: 0.2) Save; As: PNG Format; Interlace: None; Filter: Adaptive; Compression: 9.These settings best preserve fine details through the enlargement process.<br><br>Project order 46a<br>
DOI: 10.6084/m9.figshare.3187663
title: rfigshare upload test

description: Upload files to figshare using rfigshare as described at https://github.com/lcolladotor/rfigshare_test
DOI: 10.6084/m9.figshare.3187663.v1
title: rfigshare upload test

description: Upload files to figshare using rfigshare as described at https://github.com/lcolladotor/rfigshare_test
DOI: 10.6084/m9.figshare.3187685.v2
title: 22 July 2014 VID00001 Enhanced Frames No Denoise

description: Segment of frames of VID00001 taken on 22 July 2014. Frames bracket the best single frame at VID00001 0 20 28-60. Frames are extracted using Cisco FlipShare software distributed with the Cisco Flip UltraHD 720p digital video recorder used to record the video. Frames are then enhanced using Adobe Photoshop Creative Cloud as follows:1) Image Size; Width 300%; Resolution: 300 per inch; With Scale Styles; With Constrain Proportions; Interpolation: preserve details; Noise: 0.2) Save; As: PNG Format; Interlace: None; Filter: Adaptive; Compression: 9.These settings best preserve fine details through the enlargement process.<b></b><i></i><sub></sub><sup></sup><br><br>