cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.6503171.v1
title: Association between hematological profile and serum 25-hydroxyvitamin D levels and FokI polymorphism in individuals with cystic fibrosis

description: ABSTRACT Objective The present study aimed at investigating the association between hematological profile and serum 25-hydroxyvitamin D (25[OH]D) levels and Fokl polymorphism of the vitamin D receptor gene in individuals with Cystic Fibrosis. Methods A cross-sectional study that involved 18 men and women aged 0-25 years with Cystic Fibrosis. Socio-demographic information and the factors associated with sun exposure were obtained. Weight, height, and arm circumference were also measured. Blood sample was collected for the analysis of biochemical parameters (25[OH]D, parathyroid hormone, and calcium levels and blood count) and for the validation of the presence of FokI polymorphism in the vitamin D receptor gene. Results Among the participants, 33.33% (n=6) had vitamin D deficiency (19.60±6.180 ng/mL), and 27.8% (n=5) presented with anemia and low weight for age. In terms of genotype, 5.6% (n=1) presented with the FF genotype, 72.3% (n=13) had the Ff genotype, and 22.2% (n=4) had the ff genotype. Serum 25(OH)D levels were associated with hemoglobin (p=0.008) and hematocrit (p=0.019) levels and leukocyte count (p=0.0114). No association was observed between 25(OH)D levels and the genotypes (FF, Ff, and ff) (p=0.2451). In addition, an association was observed between FokI polymorphism and the total leukocyte count (p=0.01). Conclusion An association was observed between serum 25(OH)D levels and hemoglobin and hematocrit levels and leukocyte count in individuals with Cystic Fibrosis. Moreover, FokI polymorphism was associated with total leukocyte count.
DOI: 10.6084/m9.figshare.6503168
title: Chondroblastic osteosarcoma of the mandible: case report

description: ABSTRACT We report the case of a 32-year-old male patient, who was subjected to cone-beam tomography for planning the removal of an unerupted tooth. Cone-beam CT scans revealed the presence of a mixed lesion with poorly defined limits in the left posterior mandibular region, with "sun-ray" periosteal reaction. An incisional biopsy was performed and the diagnosis was chondroblastic osteosarcoma. In this paper, a discussion of the differential diagnosis criteria and treatment of this unusual malignant neoplasm is performed. Thus, it is intended to provide information that will help in the study of management protocols for the increasingly effective treatment of gnathic osteosarcomas.
DOI: 10.6084/m9.figshare.6503168.v1
title: Chondroblastic osteosarcoma of the mandible: case report

description: ABSTRACT We report the case of a 32-year-old male patient, who was subjected to cone-beam tomography for planning the removal of an unerupted tooth. Cone-beam CT scans revealed the presence of a mixed lesion with poorly defined limits in the left posterior mandibular region, with "sun-ray" periosteal reaction. An incisional biopsy was performed and the diagnosis was chondroblastic osteosarcoma. In this paper, a discussion of the differential diagnosis criteria and treatment of this unusual malignant neoplasm is performed. Thus, it is intended to provide information that will help in the study of management protocols for the increasingly effective treatment of gnathic osteosarcomas.
DOI: 10.6084/m9.figshare.6503165
title: Sialolithiasis in equine: case report

description: ABSTRACT Sialolithiasis is a condition that affects the salivary glands or their ducts, characterized by the presence of calcified structures, called sialolites, with slow and gradual growth, usually asymptomatic, hindering or impeding the normal flow of saliva. Due to the absence of reports in the national literature, the case of a 15-year-old mare who had a 13cm sialolite in the parotid duct near the face ridge for more than 2 years is described. The diagnosis was made through clinical examination: with visualization and palpation of the sialolite, dental evaluation; and complementary exams: radiography and ultrasonography. We chose surgical treatment through percutaneous access, which is the most appropriate for large stones, and Stenon's duct suture was performed, without postoperative fistulas. The assessment and dental care during the procedure was extremely important, since the dental tips facilitate the formation of the stones.
DOI: 10.6084/m9.figshare.6503165.v1
title: Sialolithiasis in equine: case report

description: ABSTRACT Sialolithiasis is a condition that affects the salivary glands or their ducts, characterized by the presence of calcified structures, called sialolites, with slow and gradual growth, usually asymptomatic, hindering or impeding the normal flow of saliva. Due to the absence of reports in the national literature, the case of a 15-year-old mare who had a 13cm sialolite in the parotid duct near the face ridge for more than 2 years is described. The diagnosis was made through clinical examination: with visualization and palpation of the sialolite, dental evaluation; and complementary exams: radiography and ultrasonography. We chose surgical treatment through percutaneous access, which is the most appropriate for large stones, and Stenon's duct suture was performed, without postoperative fistulas. The assessment and dental care during the procedure was extremely important, since the dental tips facilitate the formation of the stones.
DOI: 10.6084/m9.figshare.6503162
title: “Zero nada, zero”: Indians Guimarães Rosa, his speech

description: ABSTRACT This work examines the chronicle “Uns índios (sua fala)”, published by Guimarães Rosa in the journal A manhã (1954). In this chronicle, the writer recounts his encounter, in the state of Mato Grosso, with Tereno Indians, and his expedition to an indigenous camp in search of some secrets of the surprising Tariano language. As the chronicle implies, the seeming unintelligibility of the Tariano language is an effect of the intervention of those who want to catalog it or capture it in a writing device, and the "Indian" and "White" identities are effects produced in writing, as are the distinctions between "civilization" and "barbarism". This paper will attempt to demonstrate how this chronicle reflects some of the aspects that require reformulating the renowned documentary nature of the Guimarães Rosa corpus, as well as modifying some of the presuppositions of our reading instruments, which are generally held captive by a representational imperative.
DOI: 10.6084/m9.figshare.6503162.v1
title: “Zero nada, zero”: Indians Guimarães Rosa, his speech

description: ABSTRACT This work examines the chronicle “Uns índios (sua fala)”, published by Guimarães Rosa in the journal A manhã (1954). In this chronicle, the writer recounts his encounter, in the state of Mato Grosso, with Tereno Indians, and his expedition to an indigenous camp in search of some secrets of the surprising Tariano language. As the chronicle implies, the seeming unintelligibility of the Tariano language is an effect of the intervention of those who want to catalog it or capture it in a writing device, and the "Indian" and "White" identities are effects produced in writing, as are the distinctions between "civilization" and "barbarism". This paper will attempt to demonstrate how this chronicle reflects some of the aspects that require reformulating the renowned documentary nature of the Guimarães Rosa corpus, as well as modifying some of the presuppositions of our reading instruments, which are generally held captive by a representational imperative.
DOI: 10.6084/m9.figshare.6503156
title: Fungal dermatitis associated to Rhodotorula glutinis in dog (Canis familiaris): case report

description: ABSTRACT The fungi Rhodotorula sp was considered nonpathogenic, but with the increase of immunosuppressed humans in the last two decades, the species R. mucilaginosa, R. glutinis and R. minuta became potentially pathogenic agents. There have been few veterinary clinical reports associated with Rhodotorula spp. and this work aims to describe the first case of fungal dermatitis caused by R. glutinis in immunosuppressed dog due to visceral leishmaniasis and osteosarcoma in the city of Cuiabá-Mato Grosso. An 11-year-old male mongrel dog was examined to the Veterinary Hospital with skin lesions and the diagnosis was dermatophytosis and the treatment was implemented with topical tea tree oil for one month, but the treatment failed. The animal returned to the Veterinary Hospital with bleeding in the injured area of the tail and biopsy was performed for microbiological and histopathology evaluation. In the microbiological and histopathological analysis, yeast was isolated and yeast-like structures in silver staining were observed, respectively. The isolated yeast was identified as R. glutinis by DNA sequencing. A new treatment was implemented without clinical improvement. The animal was diagnosed with leishmaniasis and osteosarcoma, which probably caused immunosuppression, and its clinical conditions evolved to death.
DOI: 10.6084/m9.figshare.6503156.v1
title: Fungal dermatitis associated to Rhodotorula glutinis in dog (Canis familiaris): case report

description: ABSTRACT The fungi Rhodotorula sp was considered nonpathogenic, but with the increase of immunosuppressed humans in the last two decades, the species R. mucilaginosa, R. glutinis and R. minuta became potentially pathogenic agents. There have been few veterinary clinical reports associated with Rhodotorula spp. and this work aims to describe the first case of fungal dermatitis caused by R. glutinis in immunosuppressed dog due to visceral leishmaniasis and osteosarcoma in the city of Cuiabá-Mato Grosso. An 11-year-old male mongrel dog was examined to the Veterinary Hospital with skin lesions and the diagnosis was dermatophytosis and the treatment was implemented with topical tea tree oil for one month, but the treatment failed. The animal returned to the Veterinary Hospital with bleeding in the injured area of the tail and biopsy was performed for microbiological and histopathology evaluation. In the microbiological and histopathological analysis, yeast was isolated and yeast-like structures in silver staining were observed, respectively. The isolated yeast was identified as R. glutinis by DNA sequencing. A new treatment was implemented without clinical improvement. The animal was diagnosed with leishmaniasis and osteosarcoma, which probably caused immunosuppression, and its clinical conditions evolved to death.
DOI: 10.6084/m9.figshare.6503153
title: Segmentation Methods for Micro CT Images: A Comparative Study Using Human Bone Samples

description: Abstract X-ray microtomography (microCT) is a nondestructive technique used to assess bone morphometry. For an accurate analysis, it is necessary to segment the bone tissue from the background images, avoiding under- or overestimation of the real bone volume. Thus, segmentation methods for microCT can influence the accuracy of bone morphometry analysis. The purpose of this study was to compare two different image segmentation methods available on microCT software (subjective and objective) regarding to the human bone morphometric analysis. Sixteen samples containing a fixation screws covered by 0.5-1mm of bone were scanned using the SkyScan 1173 scanner. Three examiners segmented the microCT images subjectively and recorded the threshold values. Subsequently, an objective segmentation was also done. The 3D analysis was performed for both images using the values previously determined in CTAn software. Five bone morphometric parameters were calculated (BV/TV, Tb.Th, Tb.N, Tb.Sp, Conn.Den) and used as dependent variables. ANOVA showed no significant differences between the methods concerning BV/TV (p=0.424), Tb.N (p=0.672), Tb.Th (p=0.183), Tb.Sp (p=0.973) and Conn.Den (p=0.204). Intra- and interobserver agreement ranged from satisfactory to excellent (0.55-1 and 0.546-0.991, respectively). Therefore, results obtained with subjective threshorlding were similar to those obtained with objective segmentation. Since objective segmentation does not have human input and it is a truly objective method, it should be the first choice in microCT studies that concern homogeneity and high resolution human bone sample.
DOI: 10.6084/m9.figshare.6503144
title: INFLUENCE OF JOINT HIPERMOBILITY ON POSTOPERATIVE RESULTS OF KNEE SURGERY

description: ABSTRACT Objective: To evaluate the prevalence of joint hypermobility in patients undergoing knee surgery to treat traumatic injury to the meniscus and anterior cruciate ligament, and the influence of this hypermobility on postoperative results. Methods: This prospective study assessed joint hypermobility in patients who underwent surgical reconstruction of the anterior cruciate ligament (ACL), partial meniscectomy, or a procedure combining ACL reconstruction and partial meniscectomy during the period 2011-2015. The Beighton score was used to evaluate joint hypermobility and Tegner activity scale for postoperative assessment. Results: A total of 242 patients underwent surgery during the study period: 107 to treat ACL injuries, 75 to treat ACL injuries associated with meniscus injuries, and 60 to treat meniscus injuries. Of the total, 45 patients had joint hypermobility. We found no association between joint hypermobility and sex or type of injury. Postoperative Tegner scale results were not influenced by the presence of joint hypermobility. Conclusion: No association was found between joint hypermobility and the evaluated variables (gender and type of specific injury), and hypermobility did not have a negative impact on postoperative outcomes. Level of Evidence IV; Case series.
DOI: 10.6084/m9.figshare.6503144.v1
title: INFLUENCE OF JOINT HIPERMOBILITY ON POSTOPERATIVE RESULTS OF KNEE SURGERY

description: ABSTRACT Objective: To evaluate the prevalence of joint hypermobility in patients undergoing knee surgery to treat traumatic injury to the meniscus and anterior cruciate ligament, and the influence of this hypermobility on postoperative results. Methods: This prospective study assessed joint hypermobility in patients who underwent surgical reconstruction of the anterior cruciate ligament (ACL), partial meniscectomy, or a procedure combining ACL reconstruction and partial meniscectomy during the period 2011-2015. The Beighton score was used to evaluate joint hypermobility and Tegner activity scale for postoperative assessment. Results: A total of 242 patients underwent surgery during the study period: 107 to treat ACL injuries, 75 to treat ACL injuries associated with meniscus injuries, and 60 to treat meniscus injuries. Of the total, 45 patients had joint hypermobility. We found no association between joint hypermobility and sex or type of injury. Postoperative Tegner scale results were not influenced by the presence of joint hypermobility. Conclusion: No association was found between joint hypermobility and the evaluated variables (gender and type of specific injury), and hypermobility did not have a negative impact on postoperative outcomes. Level of Evidence IV; Case series.
DOI: 10.6084/m9.figshare.6503141
title: Essential oils from Citrus x aurantium and Citrus x latifolia (Rutaceae) have anesthetic activity and are effective in reducing ion loss in silver catfish ( Rhamdia quelen )

description: ABSTRACT This study investigated the anesthetic effect of the essential oils (EOs) from the peel of Citrus x aurantium (EOCA) and Citrus x latifolia (EOCL) on silver catfish Rhamdia quelen. Fish were exposed to different concentrations of EOCA and EOCL to determine time of anesthesia induction and recovery. Induction of anesthesia was observed in all fish exposed to 400, 600 or 800 μL L−1 EOCA and 300, 400 or 500 μL L−1 EOCL. Another group of fish were exposed for 8 h to 50, 100, or 200 μL L−1 of either EOs. Overall, fish exposed to ethanol and both EOs presented higher ventilatory frequencies (VF) than the control group throughout the 8 h of exposure. Net ion (Na+, K+ and Cl−) effluxes and ammonia excretion were significantly lower in fish exposed to 50, 100 or 200 μL L−1 of either EOs compared to control fish. Mortality was 37% in fish exposed to 200 μL L−1 of either EOs after 8 h. These findings suggest that EOCA and EOCL are useful anesthetics and sedatives for Rhamdia quelen, but their usefulness as alternatives to reduce stress in fish transportation at the lower concentrations tested (50-100 µL L−1) deserves further study.
DOI: 10.15468/dl.u7px85
title: Occurrence Download

description: A dataset containing 1 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Limonium teuchirae Brullo"
 ]
}

 The dataset includes 1 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0046707-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.ds7yju
title: Occurrence Download

description: A dataset containing 14 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Liparis stolzii Schltr."
 ]
}

 The dataset includes 14 records from 10 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0046708-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.yduun2
title: Occurrence Download

description: A dataset containing 994 species occurrences available in GBIF matching the query:
{
 "DatasetKey" : [
 "is NEON Biorepository Benthic Macroinvertebrate Collection (Unsorted Bulk Sample)"
 ]
}

 The dataset includes 994 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0046709-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.bwfc9v
title: Occurrence Download

description: A dataset containing 7 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Limonium thaenicum Brullo & Erben"
 ]
}

 The dataset includes 7 records from 4 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0046710-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.fsy2dy
title: Occurrence Download

description: A dataset containing 100 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is China",
 "OccurrenceStatus is Present",
 "TaxonKey is one of (Acrostichum speciosum Willd., Acrostichum aureum L.)",
 "Year 2000-2024"
 ]
}

 The dataset includes 100 records from 4 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0046711-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.3qxf3s
title: Occurrence Download

description: A dataset containing 285 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Liparis stricklandiana Rchb.f."
 ]
}

 The dataset includes 285 records from 30 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0046712-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.25496845
title: Supplementary Material for: IDN5706 inhibits synovial inflammation via inducing M2 polarization of synovial macrophages in osteoarthritis rats

description: Introduction: IDN5706 is a tetrahydro derivative of hyperforin. In this study, we aimed to explore the effect of IDN5706 on synovial macrophages in osteoarthritis (OA) rats, and the underlying mechanisms. 
Methods: OA rats were employed for the in vivo experiments, and RAW264.7 cells were employed for the in vitro experiments. Histopathological changes in synovium were examined using hematoxylin and eosin (HE) staining; Cell apoptosis in synovium was assessed by TUNEL staining; Macrophages polarization was determined by immunohistochemical analysis and flow cytometry; The mRNA expression and protein level of genes were detected by qRT-PCR and western blot; The efferocytosis of macrophages was assessed by flow cytometry. 
Results: IDN5706 reversed the increased CD86-positive cells (M1 macrophages) and decreased CD206-positive cells (M2 macrophages), both in synovium and synovial fluid of OA rats. The in vitro experiments further confirmed the promotion effect of IDN5706 on M2 macrophages, accompanied by the elevated Arg-1 and reduced iNOS. Also, the up-regulated p-mTOR in synovium and synovial fluid of OA rats were reversed by IDN5706, and the decreased M1 macrophages and increased M2 macrophages induced by IDN5706 were reversed by mTOR activator. IDN5706 enhanced the efferocytosis of IL-4 treated RAW264.7 cells, and the animal experiments further revealed the involvement of efferocytosis in the improvement of OA by IDN5706. 
Conclusions: IDN5706 enhanced the efferocytosis of synovial macrophages by inducing M2 polarization via inhibiting p-mTOR, thus suppressing synovial inflammation and OA development, providing a theoretical basis for IDN5706 as a clinical drug for inflammatory diseases.
DOI: 10.6084/m9.figshare.25496845.v1
title: Supplementary Material for: IDN5706 inhibits synovial inflammation via inducing M2 polarization of synovial macrophages in osteoarthritis rats

description: Introduction: IDN5706 is a tetrahydro derivative of hyperforin. In this study, we aimed to explore the effect of IDN5706 on synovial macrophages in osteoarthritis (OA) rats, and the underlying mechanisms. 
Methods: OA rats were employed for the in vivo experiments, and RAW264.7 cells were employed for the in vitro experiments. Histopathological changes in synovium were examined using hematoxylin and eosin (HE) staining; Cell apoptosis in synovium was assessed by TUNEL staining; Macrophages polarization was determined by immunohistochemical analysis and flow cytometry; The mRNA expression and protein level of genes were detected by qRT-PCR and western blot; The efferocytosis of macrophages was assessed by flow cytometry. 
Results: IDN5706 reversed the increased CD86-positive cells (M1 macrophages) and decreased CD206-positive cells (M2 macrophages), both in synovium and synovial fluid of OA rats. The in vitro experiments further confirmed the promotion effect of IDN5706 on M2 macrophages, accompanied by the elevated Arg-1 and reduced iNOS. Also, the up-regulated p-mTOR in synovium and synovial fluid of OA rats were reversed by IDN5706, and the decreased M1 macrophages and increased M2 macrophages induced by IDN5706 were reversed by mTOR activator. IDN5706 enhanced the efferocytosis of IL-4 treated RAW264.7 cells, and the animal experiments further revealed the involvement of efferocytosis in the improvement of OA by IDN5706. 
Conclusions: IDN5706 enhanced the efferocytosis of synovial macrophages by inducing M2 polarization via inhibiting p-mTOR, thus suppressing synovial inflammation and OA development, providing a theoretical basis for IDN5706 as a clinical drug for inflammatory diseases.
DOI: 10.15468/dl.gfmg3p
title: Occurrence Download

description: A dataset containing 186 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Limonium thiniense Erben"
 ]
}

 The dataset includes 186 records from 21 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0046713-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.m6sgzz
title: Occurrence Download

description: A dataset containing 25 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Liparis suborbicularis Summerh."
 ]
}

 The dataset includes 25 records from 11 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0046714-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.