cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.3481949.v2
title: Exemplar OCC dataset from Springer Nature metadata

description: This archive contains an exemplar dataset of the information obtained running the main tools used for building the OpenCitations Corpus (http://opencitations.net) on the metadata of the 67 articles included in the Proceedings of the 14th International Semantic Web Conference gently provided by Springer Nature.<br><br>Some statistics of the information in this dataset:<br>- number of citing/cited objects: 1441<br>- number of citations: 1531<br>- number of containers (journals, proceedings, books, etc.): 411<br>- number of publishers: 42<br>- number of authors: 3076<br>- number of authors with ORCID: 157<br>- number of RDF statements: 69995<br>
DOI: 10.6084/m9.figshare.3481949.v1
title: Exemplar OCC dataset from Springer-Nature metadata

description: This archive contains an exemplar dataset of the information obtained running the main tools used for building the OpenCitations Corpus (http://opencitations.net) on the metadata of the 67 articles included in the Proceedings of the 14th International Semantic Web Conference gently provided by Springer Nature.<br><br>Some statistics of the information in this dataset:<br>- number of citing/cited objects: 1441<br>- number of citations: 1531<br>- number of containers (journals, proceedings, books, etc.): 411<br>- number of publishers: 42<br>- number of authors: 3076<br>- number of authors with ORCID: 157<br>- number of RDF statements: 69995<br>
DOI: 10.6084/m9.figshare.3481922
title: Exemplar OCC dataset from Europe PubMed Central metadata

description: This archive contains an exemplar dataset of the information obtained running the main tools used for building the OpenCitations Corpus (http://opencitations.net) on the metadata of 67 articles gathered from Europe PubMed Central.<br><br>Some statistics of the information in this dataset:<br>- number of citing/cited objects: 3391<br>- number of citations: 3337<br>- number of containers (journals, proceedings, books, etc.): 1047<br>- number of publishers: 137<br>- number of authors: 21658<br>- number of authors with ORCID: 957<br>- number of RDF statements: 377237<br>
DOI: 10.6084/m9.figshare.3481922.v1
title: Exemplar OCC dataset from Europe PubMed Central metadata

description: This archive contains an exemplar dataset of the information obtained running the main tools used for building the OpenCitations Corpus (http://opencitations.net) on the metadata of 67 articles gathered from Europe PubMed Central.<br><br>Some statistics of the information in this dataset:<br>- number of citing/cited objects: 3391<br>- number of citations: 3337<br>- number of containers (journals, proceedings, books, etc.): 1047<br>- number of publishers: 137<br>- number of authors: 21658<br>- number of authors with ORCID: 957<br>- number of RDF statements: 377237<br>
DOI: 10.6084/m9.figshare.3481811
title: Conformational and structural study of <i>N</i>-nicotinyl <i>N′, N</i>″-bis(diisobutyl amine)phosphoric triamide

description: Single crystals of C5H4NC(O)NHP(O)[N(i-C4H9)2]2 were prepared and investigated by X-ray crystallography. Interestingly, four symmetrically independent conformers were detected in the structure of this compound by X-ray crystallography. The greatest difference in these conformers was different torsion angles. In all conformers, the phosphoryl and carbonyl groups showed anti-configurations, and the two terminal CH3 groups of each alkyl chain in amine parts have different spatial orientations due to their connection to a prochiral carbon atom. The diastereotopic protons of every CH2 moiety in amine groups also have different spatial orientations. Every conformer forms a centrosymmetric dimer with its own symmetrically generated analog via a hydrogen bond. The first conformer connects to others (A, B, and C) via electrostatic interactions and forms a tetramer. All hydrogen bonds and electrostatic interactions result in the formation of a three-dimensional polymeric network in the crystalline lattice of compound. To find the most stable conformer, density functional theory (DFT) calculations were performed. The computationally optimized geometric parameters are in good agreement with the experimental results. According to DFT calculations, B is the most stable conformer with energy of −987714.07 kcal/mol. In all conformers the electron density of HOMO is localized on P=O and C=O oxygen atoms and some parts of amine groups, while LUMO is localized on the nicotinamide part of the molecule.
DOI: 10.6084/m9.figshare.3481811.v1
title: Conformational and structural study of <i>N</i>-nicotinyl <i>N′, N</i>″-bis(diisobutyl amine)phosphoric triamide

description: Single crystals of C5H4NC(O)NHP(O)[N(i-C4H9)2]2 were prepared and investigated by X-ray crystallography. Interestingly, four symmetrically independent conformers were detected in the structure of this compound by X-ray crystallography. The greatest difference in these conformers was different torsion angles. In all conformers, the phosphoryl and carbonyl groups showed anti-configurations, and the two terminal CH3 groups of each alkyl chain in amine parts have different spatial orientations due to their connection to a prochiral carbon atom. The diastereotopic protons of every CH2 moiety in amine groups also have different spatial orientations. Every conformer forms a centrosymmetric dimer with its own symmetrically generated analog via a hydrogen bond. The first conformer connects to others (A, B, and C) via electrostatic interactions and forms a tetramer. All hydrogen bonds and electrostatic interactions result in the formation of a three-dimensional polymeric network in the crystalline lattice of compound. To find the most stable conformer, density functional theory (DFT) calculations were performed. The computationally optimized geometric parameters are in good agreement with the experimental results. According to DFT calculations, B is the most stable conformer with energy of −987714.07 kcal/mol. In all conformers the electron density of HOMO is localized on P=O and C=O oxygen atoms and some parts of amine groups, while LUMO is localized on the nicotinamide part of the molecule.
DOI: 10.6084/m9.figshare.3481748
title: Influenza vaccination of pregnant women protects them over two consecutive influenza seasons in a randomized controlled trial

description: <b>Background</b>: We assessed the persistence of hemagglutinin inhibition (HAI) antibodies and the vaccine efficacy (VE) of trivalent inactivated influenza vaccine (IIV3) following vaccination of a cohort of pregnant South African women during a second influenza season. <b>Methods</b>: A cohort of women who participated in a randomized placebo-controlled trial on the safety, immunogenicity and efficacy of IIV3 in 2011 had HAI titers measured in 2012 and were monitored for influenza illness until the end of 2012. <b>Results</b>: The proportion of women with HAI titers ≥1:40 was significantly greater in vaccinees (63%) compared to placebo-recipients (22%; p <b>Conclusion</b>: The majority of women who received IIV3 during pregnancy had HAI titers above the putative threshold for protection against influenza illness one year after vaccination and showed a trend towards protection against influenza disease.
DOI: 10.6084/m9.figshare.3481748.v1
title: Influenza vaccination of pregnant women protects them over two consecutive influenza seasons in a randomized controlled trial

description: <b>Background</b>: We assessed the persistence of hemagglutinin inhibition (HAI) antibodies and the vaccine efficacy (VE) of trivalent inactivated influenza vaccine (IIV3) following vaccination of a cohort of pregnant South African women during a second influenza season. <b>Methods</b>: A cohort of women who participated in a randomized placebo-controlled trial on the safety, immunogenicity and efficacy of IIV3 in 2011 had HAI titers measured in 2012 and were monitored for influenza illness until the end of 2012. <b>Results</b>: The proportion of women with HAI titers ≥1:40 was significantly greater in vaccinees (63%) compared to placebo-recipients (22%; p <b>Conclusion</b>: The majority of women who received IIV3 during pregnancy had HAI titers above the putative threshold for protection against influenza illness one year after vaccination and showed a trend towards protection against influenza disease.
DOI: 10.6084/m9.figshare.3481709
title: The two sides of adversity: the effect of distant versus recent adversity on updating emotional content in working memory

description: Previous research suggests that adversity can have both adaptive and maladaptive effects, yet the emotional and working memory processes that contribute to more or less adaptive outcomes are unclear. The present study sought to investigate how updating emotional content differs in adolescents who have experienced past, recent, or no adversity. Participants who had experienced distant adversity (<i>N</i> = 53), no adversity (<i>N</i> = 58), or recent adversity only (<i>N</i> = 20) performed an emotion <i>n</i>-back task with emotional facial expressions. Results revealed that the distant adversity group exhibited significantly <i>faster</i> reaction times (RTs) than the no adversity and recent adversity only groups. In contrast, the recent adversity only group exhibited significantly <i>slower</i> RTs and more errors than the distant adversity and no adversity groups. These results suggest an emotion and executive control pathway by which both the benefits and negative effects of adversity may be conferred. Results also highlight the importance of time in assessing the impact of adversity.
DOI: 10.6084/m9.figshare.3481709.v1
title: The two sides of adversity: the effect of distant versus recent adversity on updating emotional content in working memory

description: Previous research suggests that adversity can have both adaptive and maladaptive effects, yet the emotional and working memory processes that contribute to more or less adaptive outcomes are unclear. The present study sought to investigate how updating emotional content differs in adolescents who have experienced past, recent, or no adversity. Participants who had experienced distant adversity (<i>N</i> = 53), no adversity (<i>N</i> = 58), or recent adversity only (<i>N</i> = 20) performed an emotion <i>n</i>-back task with emotional facial expressions. Results revealed that the distant adversity group exhibited significantly <i>faster</i> reaction times (RTs) than the no adversity and recent adversity only groups. In contrast, the recent adversity only group exhibited significantly <i>slower</i> RTs and more errors than the distant adversity and no adversity groups. These results suggest an emotion and executive control pathway by which both the benefits and negative effects of adversity may be conferred. Results also highlight the importance of time in assessing the impact of adversity.
DOI: 10.6084/m9.figshare.3481700
title: Validez estructural de la escala de autorregulación del aprendizaje para estudiantes universitarios / Structural validity of the learning self-regulation questionnaire for university students

description: <b>RESUMEN: </b>El objetivo del estudio fue obtener evidencias de validez de la estructura interna del Cuestionario de Autorregulación del Aprendizaje (Learning Self-Regulation Questionnaire; LSRQ) y verificar la invarianza métrica comparada con un estudio previo. Los participantes fueron 237 estudiantes universitarios de los tres primeros ciclos académicos de una universidad privada, procedentes de tres ciudades del Perú (dos del norte y una de Lima). El análisis se realizó mediante un análisis factorial semiconfirmatorio, especificando como matriz de comparación (a) la configuración derivada de un estudio previo, y (b) la estimación libre de las cargas factoriales. Los resultados indican que dos dimensiones representan satisfactoriamente la estructura del instrumento; pero la invarianza métrica respecto a un estudio previo no fue satisfactoria. La reespecificación del modelo, mediante la eliminación de dos ítems con problemas de complejidad factorial y la estimación libre de los ítems, obtuvieron resultados satisfactorios. Se discuten estos resultados en el marco de la interpretación de sus puntajes y la falta de invarianza métrica.<br><b>DESCRIPCIÓN: </b>The study’s aim was to obtain evidence of validity of the Learning Self-Regulation Questionnaire (LSRQ) internal structure and to verify metric invariance compared with a previous research study. The participants were 237 university students from the first three academic semesters of a private university in three Peruvian cities (two in the North of Peru, and one in Lima). The analysis was performed by a semi-confirmatory factor analysis, specifying as comparison matrix: a) the configuration derived from a previous study, and b) the free estimation loadings factors. The results indicate that two dimensions represent the instrument structure satisfactorily; but the metric invariance compared to a previous study was not satisfactory. The re-specification of the model, by removing two items with factorial complexity problems and the free estimation of the items, was successful. These results are discussed so as to the interpretation of their scores and the lack of metric invariance.<br><br><b>AUTORES: </b><b>Chávez Ventura, Gina</b>; <b>Merino Soto, César</b><b>EDITORIAL: </b><b>Universidad Peruana de Ciencias Aplicadas (UPC)</b><b>REVISTA: </b><b>Revista Digital de Investigación en Docencia Universitaria (RIDU)</b><b>FECHA DE PUBLICACIÓN: </b>DIC-2015<b>PDF: FULLTEXT / TEXTO COMPLETO</b><b>URL: </b>http://hdl.handle.net/10757/604928<b>DOI: </b>10.19083/ridu.9.453; 10.19083/ridu.9.405
DOI: 10.6084/m9.figshare.3481688
title: High-resolution arrays reveal burden of copy number variations on Parkinson disease genes associated with increased disease risk in random cohorts

description: Background: Parkinson disease (PD) is a neurological disease responsible for a considerable rate of mortality and morbidity in the society. Since the symptoms of the disease appear much later than the actual onset of neuron degeneration, a majority of cases remain undiagnosed until the manifestation of the symptoms. Objectives: In order to investigate the existence of such susceptibility in the population, we analyzed Copy Number Variation (CNV) influences on PD genes in 1715 individuals from 12 different populations. Results: Overall, 16 CNV-PD genes, 3 known to be causal and 13 associated, were found to be significantly enriched. PARK2, was under heavy burden with ~1% of the population containing CNV in the exonic region. The impact of these genes on the genome and disease pathway was analyzed using several genome analysis tools. Protein interaction network of CNV-PD genes revealed a complex interaction of molecules forming a major hub by the α-Synuclein, whose direct interactors, LRRK2, PARK2 and ATP13A2 are under CNV influence. Conclusions: We hypothesize that CNVs may not be the initiating event in the pathogenesis of PD and remain latent until additional secondary hits are acquired and also propose novel genes that may fall under the PD pathway which contribute in pathogenesis.
DOI: 10.6084/m9.figshare.3481688.v1
title: High-resolution arrays reveal burden of copy number variations on Parkinson disease genes associated with increased disease risk in random cohorts

description: Background: Parkinson disease (PD) is a neurological disease responsible for a considerable rate of mortality and morbidity in the society. Since the symptoms of the disease appear much later than the actual onset of neuron degeneration, a majority of cases remain undiagnosed until the manifestation of the symptoms. Objectives: In order to investigate the existence of such susceptibility in the population, we analyzed Copy Number Variation (CNV) influences on PD genes in 1715 individuals from 12 different populations. Results: Overall, 16 CNV-PD genes, 3 known to be causal and 13 associated, were found to be significantly enriched. PARK2, was under heavy burden with ~1% of the population containing CNV in the exonic region. The impact of these genes on the genome and disease pathway was analyzed using several genome analysis tools. Protein interaction network of CNV-PD genes revealed a complex interaction of molecules forming a major hub by the α-Synuclein, whose direct interactors, LRRK2, PARK2 and ATP13A2 are under CNV influence. Conclusions: We hypothesize that CNVs may not be the initiating event in the pathogenesis of PD and remain latent until additional secondary hits are acquired and also propose novel genes that may fall under the PD pathway which contribute in pathogenesis.
DOI: 10.6084/m9.figshare.3481661
title: Computational and molecular analysis of conserved influenza A virus RNA secondary structures involved in infectious virion production

description: As well as encoding viral proteins, genomes of RNA viruses harbor secondary and tertiary RNA structures that have been associated with functions essential for successful replication and propagation. Here, we identified stem-loop structures that are extremely conserved among 1,884 M segment sequences of influenza A virus (IAV) strains from various subtypes and host species using computational and evolutionary methods. These structures were predicted within the 3′ and 5′ ends of the coding regions of M1 and M2, respectively, where packaging signals have been previously proposed to exist. These signals are thought to be required for the incorporation of a single copy of 8 different negative-strand RNA segments (vRNAs) into an IAV particle. To directly test the functionality of conserved stem-loop structures, we undertook reverse genetic experiments to introduce synonymous mutations designed to disrupt secondary structures predicted at 3 locations and found them to attenuate infectivity of recombinant virus. In one mutant, predicted to disrupt stem loop structure at nucleotide positions 219–240, attenuation was more evident at increased temperature and was accompanied by an increase in the production of defective virus particles. Our results suggest that the conserved secondary structures predicted in the M segment are involved in the production of infectious viral particles during IAV replication.
DOI: 10.6084/m9.figshare.3481661.v1
title: Computational and molecular analysis of conserved influenza A virus RNA secondary structures involved in infectious virion production

description: As well as encoding viral proteins, genomes of RNA viruses harbor secondary and tertiary RNA structures that have been associated with functions essential for successful replication and propagation. Here, we identified stem-loop structures that are extremely conserved among 1,884 M segment sequences of influenza A virus (IAV) strains from various subtypes and host species using computational and evolutionary methods. These structures were predicted within the 3′ and 5′ ends of the coding regions of M1 and M2, respectively, where packaging signals have been previously proposed to exist. These signals are thought to be required for the incorporation of a single copy of 8 different negative-strand RNA segments (vRNAs) into an IAV particle. To directly test the functionality of conserved stem-loop structures, we undertook reverse genetic experiments to introduce synonymous mutations designed to disrupt secondary structures predicted at 3 locations and found them to attenuate infectivity of recombinant virus. In one mutant, predicted to disrupt stem loop structure at nucleotide positions 219–240, attenuation was more evident at increased temperature and was accompanied by an increase in the production of defective virus particles. Our results suggest that the conserved secondary structures predicted in the M segment are involved in the production of infectious viral particles during IAV replication.
DOI: 10.6084/m9.figshare.3481649
title: elastin edge linking

description: elastin
DOI: 10.6084/m9.figshare.3481649.v2
title: elastin edge linking

description: elastin
DOI: 10.6084/m9.figshare.3481649.v1
title: process_link_by_laplacian.m

description: elastin
DOI: 10.6084/m9.figshare.3481646
title: Highly optimized statistical modeling of genome-scale count data

description: Talk given at International Biometrics Conference, Victoria, July 2016<br>Session: Modelling Count Data in the Era of Next Generation Sequencing Data<br>http://f1000research.com/articles/5-1356/v1http://genomebiology.biomedcentral.com/articles/10.1186/s13059-015-0862-3http://f1000research.com/articles/4-1521/v2<br><br>
DOI: 10.6084/m9.figshare.3479660
title: RAW DATA. Attitudes toward mental illness among college students in Nuevo León, México

description: These are raw data from a survey conducted from October 2014 to February 2015 in the Universidad Autonoma de Nuevo Leon (UANL), Mexico. The survey assessed attitudes toward mental illness in students of this University.
DOI: 10.6084/m9.figshare.3479660.v1
title: RAW DATA. Attitudes toward mental illness among college students in Nuevo León, México

description: These are raw data from a survey conducted from October 2014 to February 2015 in the Universidad Autonoma de Nuevo Leon (UANL), Mexico. The survey assessed attitudes toward mental illness in students of this University.
DOI: 10.6084/m9.figshare.3479657
title: Relationship of the Tarim Craton to the Central Asian Orogenic Belt: insights from Devonian intrusions in the northern margin of Tarim Craton, China

description: The boundary and relation of the Tarim Craton to the Central Asian Orogenic Belt (CAOB) and its role in the formation history of the CAOB remain controversial. This article presents ages and Hf-in-zircon isotopic and geochemical results for gabbroic, dioritic, and granitic plutons from the northern margin of Tarim Craton (NMTC), and discusses their petrogenesis and tectonic regimes as well as the boundary between the CAOB and the Tarim Craton. These plutons yield zircon ages of 424–385 Ma. In the Quruqtagh zone south of the Xinger Fault, the gabbroic pluton shows enrichment in LREEs and LILEs, depletion in HFSEs and positive <i>ε</i><sub>Hf</sub>(<i>t</i>) values (+4.0 to +11.4), suggesting that parental magmas of gabbros were likely derived by partial melting of a depleted mantle wedge previously metasomatized by slab-derived aqueous fluids. In the Hulashan Zone north of the Xinger Fault, the studied rocks include one dioritic pluton and three granitic plutons. The geochemical characteristics and petrogenesis of the dioritic pluton are similar to those of the studied gabbroic with positive <i>ε</i><sub>Hf</sub>(<i>t</i>) values (+3.0 to +9.4). The three granitic plutons display relative depletion in HFSEs and enrichment in LILEs. Their variable <i>ε</i><sub>Hf</sub>(<i>t</i>) values range from −2.1 to +8.9, with <i>T</i><sub>DM2</sub> ages of 858–1503 Ma, suggesting complex crustal sources with different proportions of juvenile and ancient materials. This article confirms and evidences an Andean-style active continental margin of the Tarim Craton due to southward subduction of the South Tianshan Ocean. Furthermore, our Hf isotopic data, together with regional data from the literature, show that the Hulashan zone to the north to the Xinger Fault has younger continental materials in deep than these of NMTC south of the fault, and is similar to microcontinental fragments in the CAOB. This suggests that the Xinger fault may be the boundary between the Tarim Craton and Tianshan orogen.