cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q2nv9p4m
title: BindingDB Entry 50015335: Synthesis and bioevaluation of diaryl urea derivatives as potential antitumor agents for the treatment of human colorectal cancer.

description: Small molecule binding data for protein Cytochrome P450 1A2, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A4, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, Potassium voltage-gated channel subfamily H member 2, and Serine/threonine-protein kinase mTOR, Uniprot O00329, P05177, P08684, P10635, P11712, P33261, P42336, P42338, P42345, P48736, and Q12809
DOI: 10.7270/q2j38xfn
title: BindingDB Entry 50015336: Design and synthesis of dual inhibitors targeting snail and histone deacetylase for the treatment of solid tumour cancer.

description: Small molecule binding data for protein Histone deacetylase 1, Histone deacetylase 11, Histone deacetylase 4, and Histone deacetylase 8, Uniprot P56524, Q13547, Q96DB2, and Q9BY41
DOI: 10.7270/q2db85rr
title: BindingDB Entry 50015337: Fragment-Based Discovery of MRTX1719, a Synthetic Lethal Inhibitor of the PRMT5•MTA Complex for the Treatment of

description: Small molecule binding data for protein Methylosome protein 50/Protein arginine N-methyltransferase 5 and Protein arginine N-methyltransferase 5, Uniprot O14744 and Q9BQA1
DOI: 10.7270/q28k7f00
title: BindingDB Entry 50015338: Synthesis and Evaluation of Structurally Diverse C-2-Substituted Thienopyrimidine-Based Inhibitors of the Human Geranylgeranyl Pyrophosphate Synthase.

description: Small molecule binding data for protein Farnesyl pyrophosphate synthase and Geranylgeranyl pyrophosphate synthase, Uniprot O95749 and P14324
DOI: 10.7270/q24x5cpk
title: BindingDB Entry 50015339: Discovery of N-Trisubstituted Pyrimidine Derivatives as Type I RET and RET Gatekeeper Mutant Inhibitors with a Novel Kinase Binding Pose.

description: Small molecule binding data for protein Aurora kinase A, High affinity nerve growth factor receptor, Macrophage colony-stimulating factor 1 receptor, Mitogen-activated protein kinase kinase kinase kinase 4, Proto-oncogene tyrosine-protein kinase receptor Ret, Receptor-type tyrosine-protein kinase FLT3 [K633Q], and Serine/threonine-protein kinase Nek2, Uniprot O14965, O95819, P04629, P07333, P07949, P36888, and P51955
DOI: 10.7270/q2154mz5
title: BindingDB Entry 50015340: Synthesis, Biological Evaluation, and Molecular Modeling Studies of 3,4-Diarylpyrazoline Series of Compounds as Potent, Nonbrain Penetrant Antagonists of Cannabinoid-1 (CB

description: Small molecule binding data for protein Cannabinoid receptor 1 and Cannabinoid receptor 2, Uniprot P21554 and P34972
DOI: 10.7270/q2wd44g8
title: BindingDB Entry 50015341: A Selective and Orally Bioavailable Quinoline-6-Carbonitrile-Based Inhibitor of CDK8/19 Mediator Kinase with Tumor-Enriched Pharmacokinetics.

description: Small molecule binding data for protein Cyclin-C/Cyclin-dependent kinase 19, Cyclin-dependent kinase 19, Cyclin-dependent kinase 8, Mitogen-activated protein kinase kinase kinase kinase 2, Myosin-IIIb, and Serine/threonine-protein kinase haspin, Uniprot P24863, P49336, Q12851, Q8TF76, Q8WXR4, and Q9BWU1
DOI: 10.7270/q2rn3crj
title: BindingDB Entry 50015342: Design, Synthesis, and Biological Evaluation of 2-Formyl Tetrahydronaphthyridine Urea Derivatives as New Selective Covalently Reversible FGFR4 Inhibitors.

description: Small molecule binding data for protein Fibroblast growth factor receptor 1, Fibroblast growth factor receptor 2, Fibroblast growth factor receptor 3, and Fibroblast growth factor receptor 4, Uniprot P11362, P21802, P22455, and P22607
DOI: 10.7270/q2mw2n17
title: BindingDB Entry 50015344: Discovery of Potent, Selective, and In Vivo Efficacious AKT Kinase Protein Degraders via Structure-Activity Relationship Studies.

description: Small molecule binding data for protein RAC-alpha serine/threonine-protein kinase, RAC-beta serine/threonine-protein kinase, and RAC-gamma serine/threonine-protein kinase, Uniprot P31749, P31751, and Q9Y243
DOI: 10.7270/q2h41wb8
title: BindingDB Entry 50015345: Development of a Novel, Small-Molecule Brain-Penetrant Histone Deacetylase Inhibitor That Enhances Spatial Memory Formation in Mice.

description: Small molecule binding data for protein Histone deacetylase 1, Histone deacetylase 2, Histone deacetylase 3, Histone deacetylase 6, and Histone deacetylase 8, Uniprot O15379, Q13547, Q92769, Q9BY41, and Q9UBN7
DOI: 10.7270/q2cf9v08
title: BindingDB Entry 50015353: Discovery and Optimization of Highly Selective Inhibitors of CDK5.

description: Small molecule binding data for protein CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7, Cyclin-A2/Cyclin-dependent kinase 2, Cyclin-T1/Cyclin-dependent kinase 9, Cyclin-dependent kinase 5 activator 1, and Cyclin-dependent kinase 6/G1/S-specific cyclin-D3, Uniprot O60563, P20248, P24941, P30281, P50613, P50750, P51946, P51948, Q00534, Q00535, and Q15078
DOI: 10.7270/q27p939c
title: BindingDB Entry 50015356: Drug Repurposing of Quisinostat to Discover Novel

description: Small molecule binding data for protein Histone deacetylase 1, Histone deacetylase 2, Histone deacetylase 3, Histone deacetylase 6, Histone deacetylase 8, and NAD-dependent protein deacetylase sirtuin-2, Uniprot O15379, Q13547, Q8IXJ6, Q92769, Q9BY41, and Q9UBN7
DOI: 10.7270/q23x8bkn
title: BindingDB Entry 50015358: Synthesis and Evaluation of Novel Tetrahydronaphthyridine CXCR4 Antagonists with Improved Drug-like Profiles.

description: Small molecule binding data for protein Alpha-2A adrenergic receptor, Alpha-2C adrenergic receptor, Cytochrome P450 1A2, Cytochrome P450 2C19, Cytochrome P450 2C8, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A4, D(2) dopamine receptor, Kappa-type opioid receptor, Mu-type opioid receptor, Muscarinic acetylcholine receptor M2, Neuronal acetylcholine receptor subunit alpha-7, and Potassium voltage-gated channel subfamily H member 2, Uniprot P05177, P08172, P08684, P08913, P10632, P10635, P11712, P14416, P18825, P33261, P35372, P36544, P41145, and Q12809
DOI: 10.7270/q2057kv7
title: BindingDB Entry 50015359: Discovery of a Partial Glucokinase Activator Clinical Candidate: Diethyl ((3-(3-((5-(Azetidine-1-carbonyl)pyrazin-2-yl)oxy)-5-isopropoxybenzamido)-1

description: Small molecule binding data for protein ATP-dependent translocase ABCB1, Cytochrome P450 1A2, Cytochrome P450 2B6, Cytochrome P450 2C19, Cytochrome P450 2C8, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A4, Hexokinase-4, and Potassium voltage-gated channel subfamily H member 2, Uniprot P05177, P08183, P08684, P10632, P10635, P11712, P20813, P33261, P35557, P52792, and Q12809
DOI: 10.7270/q2vd73cb
title: BindingDB Entry 50015360: Discovery of Small-Molecule Inhibitors of the PD-1/PD-L1 Axis That Promote PD-L1 Internalization and Degradation.

description: Small molecule binding data for protein Programmed cell death 1 ligand 1 and Programmed cell death 1 ligand/protein 1, Uniprot Q15116, Q9EP73, and Q9NZQ7
DOI: 10.7270/q2qn6bp2
title: BindingDB Entry 50015361: -Aryl Mercaptopropionamides as Broad-Spectrum Inhibitors of Metallo-β-Lactamases.

description: Small molecule binding data for protein 72 kDa type IV collagenase, Matrix metalloproteinase-14, and VIM-1 metallo-beta-lactamase, Uniprot P08253, P50281, and Q5GN09
DOI: 10.7270/q2kw5kzb
title: BindingDB Entry 50015362: Discovery of Brain-Penetrant Glucosylceramide Synthase Inhibitors with a Novel Pharmacophore.

description: Small molecule binding data for protein Ceramide glucosyltransferase, Lysosomal acid glucosylceramidase, and Sodium-dependent serotonin transporter, Uniprot O88693, P04062, P31645, and Q16739
DOI: 10.7270/q2g73jm6
title: BindingDB Entry 50015363: Structure-Based Design of a Chemical Probe Set for the 5-HT

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 1A, 5-hydroxytryptamine receptor 1B, 5-hydroxytryptamine receptor 1D, 5-hydroxytryptamine receptor 2A, 5-hydroxytryptamine receptor 2B, 5-hydroxytryptamine receptor 2C, 5-hydroxytryptamine receptor 3A, and 5-hydroxytryptamine receptor 5A, Uniprot P08908, P28221, P28222, P28223, P28335, P41595, P46098, and P47898
DOI: 10.7270/q2bg2swg
title: BindingDB Entry 50015367: Probing Fluorinated Motifs onto Dual AChE-MAO B Inhibitors: Rational Design, Synthesis, Biological Evaluation, and Early-ADME Studies.

description: Small molecule binding data for protein Acetylcholinesterase, Albumin, Amine oxidase [flavin-containing] A, Amine oxidase [flavin-containing] B, Cholinesterase, and Cytochrome P450 3A4, Uniprot P02768, P08684, P21397, P22303, P27338, and P81908
DOI: 10.7270/q26q225j
title: BindingDB Entry 50015369: Discovery of MAP855, an Efficacious and Selective MEK1/2 Inhibitor with an ATP-Competitive Mode of Action.

description: Small molecule binding data for protein Cytochrome P450 3A4, Dual specificity mitogen-activated protein kinase kinase 1, and High affinity nerve growth factor receptor, Uniprot P04629, P08684, and Q02750
DOI: 10.7270/q22z19ft
title: BindingDB Entry 50015370: Expansion of the 4-(Diethylamino)benzaldehyde Scaffold to Explore the Impact on Aldehyde Dehydrogenase Activity and Antiproliferative Activity in Prostate Cancer.

description: Small molecule binding data for protein Aldehyde dehydrogenase 1A1, Aldehyde dehydrogenase family 1 member A3, and Aldehyde dehydrogenase, dimeric NADP-preferring, Uniprot P00352, P30838, and P47895
DOI: 10.7270/q2z60szf
title: BindingDB Entry 50015373: Design, Synthesis, and Bioevaluation of 2-Aminopteridin-7(8

description: Small molecule binding data for protein Adenosine receptor A2a, Uniprot P29274
DOI: 10.7270/q2tf027h
title: BindingDB Entry 50015375: Targeting the S2 Subsite Enables the Structure-Based Discovery of Novel Highly Selective Factor XIa Inhibitors.

description: Small molecule binding data for protein Coagulation factor X, Coagulation factor XI, Plasma kallikrein, and Prothrombin, Uniprot P00734, P00742, P03951, and P03952
DOI: 10.7270/q2pn99jp
title: BindingDB Entry 50015377: Design, Synthesis, and Preclinical Profiling of GSK3739936 (BMS-986180), an Allosteric Inhibitor of HIV-1 Integrase with Broad-Spectrum Activity toward 124/125 Polymorphs.

description: Small molecule binding data for protein Potassium voltage-gated channel subfamily H member 2 and Solute carrier organic anion transporter family member 1B1, Uniprot Q12809 and Q9Y6L6
DOI: 10.7270/q2k07853
title: BindingDB Entry 50015379: Evodiamine-Inspired Topoisomerase-Histone Deacetylase Dual Inhibitors: Novel Orally Active Antitumor Agents for Leukemia Therapy.

description: Small molecule binding data for protein Histone deacetylase 1, Histone deacetylase 2, Histone deacetylase 3, Histone deacetylase 6, and Histone deacetylase 8, Uniprot O15379, Q13547, Q92769, Q9BY41, and Q9UBN7
DOI: 10.7270/q2f76hgt
title: BindingDB Entry 50015382: Resveratrol-Based MTDLs to Stimulate Defensive and Regenerative Pathways and Block Early Events in Neurodegenerative Cascades.

description: Small molecule binding data for protein Amine oxidase [flavin-containing] A and Amine oxidase [flavin-containing] B, Uniprot P21397 and P27338
DOI: 10.7270/q29g5rqn
title: BindingDB Entry 50015383: A New Class of Bi- and Trifunctional Sugar Oximes as Antidotes against Organophosphorus Poisoning.

description: Small molecule binding data for protein Acetylcholinesterase, Uniprot P22303
DOI: 10.7270/q25q510q
title: BindingDB Entry 50015384: Rational Design, Chemical Syntheses, and Biological Evaluations of Peripherally Selective Mu Opioid Receptor Ligands as Potential Opioid Induced Constipation Treatment.

description: Small molecule binding data for protein Delta-type opioid receptor, Kappa-type opioid receptor, and Mu-type opioid receptor, Uniprot P33534, P35372, P41143, P41145, and P42866
DOI: 10.7270/q21z489f
title: BindingDB Entry 50015385: Design, Synthesis, and Biological Evaluation of NAP Isosteres: A Switch from Peripheral to Central Nervous System Acting Mu-Opioid Receptor Antagonists.

description: Small molecule binding data for protein Delta-type opioid receptor, Kappa-type opioid receptor, and Mu-type opioid receptor, Uniprot P33534, P41143, and P42866
DOI: 10.7270/q2x63rt2
title: BindingDB Entry 50015387: Discovery of (

description: Small molecule binding data for protein AP2-associated protein kinase 1, ATP-binding cassette sub-family C member 2, BMP-2-inducible protein kinase, Bile salt export pump, Broad substrate specificity ATP-binding cassette transporter ABCG2, Citron Rho-interacting kinase, Cyclin-G-associated kinase, Cytochrome P450 1A2, Cytochrome P450 2B6, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A4, Glycogen synthase kinase-3 alpha, MAP kinase-interacting serine/threonine-protein kinase 1, MAP kinase-interacting serine/threonine-protein kinase 2, Potassium voltage-gated channel subfamily H member 2, Rho-associated protein kinase 2, Serine/threonine-protein kinase LATS2, Serine/threonine-protein kinase N2, Sodium-dependent noradrenaline transporter, Sodium/bile acid cotransporter, Solute carrier family 22 member 6, Solute carrier family 22 member 8, Solute carrier organic anion transporter family member 1B1, Solute carrier organic anion transporter family member 1B3, and cGMP-dependent protein kinase 2, Uniprot O14578, O14976, O75116, O95342, P05177, P08684, P10635, P11712, P20813, P23975, P33261, P49840, Q12809, Q13237, Q14973, Q16513, Q2M2I8, Q4U2R8, Q8TCC7, Q92887, Q9BUB5, Q9HBH9, Q9NPD5, Q9NRM7, Q9NSY1, Q9UNQ0, and Q9Y6L6
DOI: 10.7270/q2sf312p
title: BindingDB Entry 50015388: SAR of Novel 3-Arylisoquinolinones:

description: Small molecule binding data for protein Ribosyldihydronicotinamide dehydrogenase [quinone], Uniprot P16083
DOI: 10.7270/q2ns0zts
title: BindingDB Entry 50015389: Discovery of TAK-925 as a Potent, Selective, and Brain-Penetrant Orexin 2 Receptor Agonist.

description: Small molecule binding data for protein Orexin receptor type 2 and Orexin/Hypocretin receptor type 1, Uniprot O43613 and O43614
DOI: 10.7270/q2j10735
title: BindingDB Entry 50015390: A Chemical Strategy toward Novel Brain-Penetrant EZH2 Inhibitors.

description: Small molecule binding data for protein Histone-lysine N-methyltransferase EZH2, Uniprot Q15910
DOI: 10.7270/q2d79gbf
title: BindingDB Entry 50015392: Development of Potent and Selective Janus Kinase 2/3 Directing PG-PROTACs.

description: Small molecule binding data for protein Protein cereblon and Tyrosine-protein kinase JAK2, Uniprot O60674 and Q96SW2
DOI: 10.7270/q28g8qmq
title: BindingDB Entry 50015393: Identification of the Highly Active, Species Cross-Reactive Complex I Inhibitor BAY-179.

description: Small molecule binding data for protein Cytochrome P450 1A2, Cytochrome P450 2C8, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A4, and Potassium voltage-gated channel subfamily H member 2, Uniprot P05177, P08684, P10632, P10635, P11712, and Q12809
DOI: 10.7270/q24q7zw0
title: BindingDB Entry 50015394: Discovery of SHR5133, a Highly Potent and Novel HBV Capsid Assembly Modulator.

description: Small molecule binding data for protein Capsid protein, Cytochrome P450 1A2, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A4, and Potassium voltage-gated channel subfamily H member 2, Uniprot P05177, P08684, P10635, P11712, P33261, Q03732, and Q12809
DOI: 10.7270/q20z7752
title: BindingDB Entry 50015398: CRCM5484: A BET-BDII Selective Compound with Differential Anti-leukemic Drug Modulation.

description: Small molecule binding data for protein Bromodomain-containing protein 2, Bromodomain-containing protein 3, and Bromodomain-containing protein 4, Uniprot O60885, P25440, and Q15059
DOI: 10.7270/q2w66qpp
title: BindingDB Entry 50015399: Structure-Based Optimization of a Fragment-like TLR8 Binding Screening Hit to an

description: Small molecule binding data for protein Cytochrome P450 3A4, Potassium voltage-gated channel subfamily H member 2, Toll-like receptor 4, Toll-like receptor 7, Toll-like receptor 8, and Toll-like receptor 9, Uniprot O00206, P08684, P58681, Q12809, Q9NR96, Q9NR97, and Q9NYK1
DOI: 10.7270/q2rj4pcp
title: BindingDB Entry 50015400: Diminishing GSH-Adduct Formation of Tricyclic Diazepine-based Mutant IDH1 Inhibitors.

description: Small molecule binding data for protein Cytochrome P450 3A4, Isocitrate dehydrogenase [NADP] cytoplasmic, Isocitrate dehydrogenase [NADP], mitochondrial, and Nuclear receptor subfamily 1 group I member 2, Uniprot O75469, O75874, P08684, and P48735
DOI: 10.7270/q2ms3xpd
title: BindingDB Entry 50015402: Development of 6-Methanesulfonyl-8-nitrobenzothiazinone Based Antitubercular Agents.

description: Small molecule binding data for protein Decaprenylphosphoryl-beta-D-ribose oxidase, Uniprot P9WJF1
DOI: 10.7270/q2h135xx
title: BindingDB Entry 50015403: Discovery by Virtual Screening of an Inhibitor of CDK5-Mediated PPARγ Phosphorylation.

description: Small molecule binding data for protein Cytochrome P450 2C9 and Peroxisome proliferator-activated receptor gamma, Uniprot P11712 and P37231
DOI: 10.7270/q2c82f6m
title: BindingDB Entry 50015404: Discovery of SHR2415, a Novel Pyrrole-Fused Urea Scaffold ERK1/2 Inhibitor.

description: Small molecule binding data for protein Cyclin-dependent kinase 2, Cytochrome P450 1A2, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A4, Glycogen synthase kinase-3 beta, Mitogen-activated protein kinase 1/3, Mitogen-activated protein kinase 3, and Potassium voltage-gated channel subfamily H member 2, Uniprot P05177, P08684, P10635, P11712, P24941, P27361, P28482, P33261, P49841, and Q12809
DOI: 10.7270/q27h1pgw
title: BindingDB Entry 50015407: Discovery of Phospholipase D Inhibitors with Improved Drug-like Properties and Central Nervous System Penetrance.

description: Small molecule binding data for protein Cytochrome P450 1A2, Cytochrome P450 2B6, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A4, Phospholipase D1, Phospholipase D2, and Potassium voltage-gated channel subfamily H member 2, Uniprot O14939, P05177, P08684, P10635, P11712, P20813, P33261, Q12809, and Q13393
DOI: 10.7270/q23r0xr5
title: BindingDB Entry 50015409: Small-Molecule Inhibitor of the Oncogenic KRAS

description: Small molecule binding data for protein GTPase KRas, Uniprot P01116
DOI: 10.7270/q2000603
title: BindingDB Entry 50015410: Novel Cyclic Cyanoenone Derivatives as KEAP1Modulators for Treating Neurodegenerative Diseases.

description: Small molecule binding data for protein Nuclear factor erythroid 2-related factor 2, Uniprot Q16236
DOI: 10.7270/q2v98czm
title: BindingDB Entry 50015413: Allosteric Site on SHIP2 Identified Through Fluorescent Ligand Screening and Crystallography: A Potential New Target for Intervention.

description: Small molecule binding data for protein Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2, Uniprot O15357 and Q6P549
DOI: 10.7270/q2qj7n6v
title: BindingDB Entry 50015414: Structure-Activity Relationship Study of Dexrazoxane Analogues Reveals ICRF-193 as the Most Potent Bisdioxopiperazine against Anthracycline Toxicity to Cardiomyocytes Due to Its Strong Topoisomerase IIβ Interactions.

description: Small molecule binding data for protein DNA topoisomerase 2-alpha and DNA topoisomerase 2-beta, Uniprot P11388 and Q02880
DOI: 10.7270/q2ks6wfp
title: BindingDB Entry 50015415: Structure-Based Identification of Potent Lysine-Specific Demethylase 1 Inhibitor Peptides and Temporary Cyclization to Enhance Proteolytic Stability and Cell Growth-Inhibitory Activity.

description: Small molecule binding data for protein Lysine-specific histone demethylase 1A and REST corepressor 1, Uniprot O60341 and Q9UKL0
DOI: 10.7270/q2g164qn
title: BindingDB Entry 50015418: Targeting Acute Myelogenous Leukemia Using Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on the 2-Hydroxypyrazolo[1,5-

description: Small molecule binding data for protein Dihydroorotate dehydrogenase (quinone), mitochondrial, Uniprot Q02127
DOI: 10.7270/q2b85d1s
title: BindingDB Entry 50015420: Defining Target Engagement Required for Efficacy

description: Small molecule binding data for protein Nuclear receptor ROR-alpha, Nuclear receptor ROR-beta, and Nuclear receptor ROR-gamma, Uniprot P35398, P51449, and Q92753
DOI: 10.7270/q26h4n92
title: BindingDB Entry 50015421: Heterodimeric GW7604 Derivatives: Modification of the Pharmacological Profile by Additional Interactions at the Coactivator Binding Site.

description: Small molecule binding data for protein Estrogen receptor and Estrogen receptor beta, Uniprot P03372 and Q92731
DOI: 10.7270/q22r3wkb
title: BindingDB Entry 50015422: Discovery of tert-amine-based RORγt agonists.

description: Small molecule binding data for protein Nuclear receptor ROR-gamma, Uniprot P51449 and P51450
DOI: 10.7270/q2z323jh
title: BindingDB Entry 50015423: Design and synthesis of novel orally selective and type II pan-TRK inhibitors to overcome mutations by property-driven optimization.

description: Small molecule binding data for protein Aurora kinase A, Aurora kinase B, BDNF/NT-3 growth factors receptor, High affinity nerve growth factor receptor, and NT-3 growth factor receptor, Uniprot O14965, P04629, Q16288, Q16620, and Q96GD4
DOI: 10.7270/q2tb1bts
title: BindingDB Entry 50015425: A Versatile Sub-Nanomolar Fluorescent Ligand Enables NanoBRET Binding Studies and Single-Molecule Microscopy at the Histamine H

description: Small molecule binding data for protein Histamine H1 receptor, Histamine H2 receptor, Histamine H3 receptor, and Histamine H4 receptor, Uniprot P25021, P35367, Q9H3N8, and Q9Y5N1
DOI: 10.7270/q2pk0m21
title: BindingDB Entry 50015427: 1,4,9-Triazaspiro[5.5]undecan-2-one Derivatives as Potent and Selective METTL3 Inhibitors.

description: Small molecule binding data for protein N6-adenosine-methyltransferase catalytic subunit, Uniprot Q86U44
DOI: 10.7270/q2js9vbr
title: BindingDB Entry 50015428: Activity of

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 1A, 5-hydroxytryptamine receptor 2A, 5-hydroxytryptamine receptor 2B, 5-hydroxytryptamine receptor 2C, and 5-hydroxytryptamine receptor 7, Uniprot P08908, P28223, P28335, P34969, and P41595
DOI: 10.7270/q2f193mq
title: BindingDB Entry 50015429: Potent Inhibition of HIF1α and p300 Interaction by a Constrained Peptide Derived from CITED2.

description: Small molecule binding data for protein CREB-binding protein/Histone acetyltransferase p300, Uniprot Q09472 and Q92793
DOI: 10.7270/q2988bxf
title: BindingDB Entry 50015430: Rational Remodeling of Atypical Scaffolds for the Design of Photoswitchable Cannabinoid Receptor Tools.

description: Small molecule binding data for protein Cannabinoid receptor 1 and Cannabinoid receptor 2, Uniprot P21554 and P34972
DOI: 10.7270/q25h7m64
title: BindingDB Entry 50015431: Oxadiazepinone HBV capsid assembly modulators.

description: Small molecule binding data for protein Capsid protein, Uniprot Q03732
DOI: 10.7270/q21v5jv8
title: BindingDB Entry 50015432: Optimization of Beclin 1-Targeting Stapled Peptides by Staple Scanning Leads to Enhanced Antiproliferative Potency in Cancer Cells.

description: Small molecule binding data for protein Beclin-1, Uniprot Q14457
DOI: 10.7270/q2x352cp
title: BindingDB Entry 50015433: Development of a Selective Dual Discoidin Domain Receptor (DDR)/p38 Kinase Chemical Probe.

description: Small molecule binding data for protein Discoidin domain-containing receptor 2, Epithelial discoidin domain-containing receptor 1, Mitogen-activated protein kinase 11, Mitogen-activated protein kinase 14, Receptor-interacting serine/threonine-protein kinase 2, Ribosomal protein S6 kinase alpha-5, and Tyrosine-protein kinase ABL1, Uniprot O43353, O75582, P00519, Q08345, Q15759, Q16539, and Q16832