cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.1610405.v1
title: <b>Next-generation re-sequencing of genes involved in increased platelet reactivity in diabetic patients on acetylsalicylic acid</b>

description: The objective of this study was to investigate whether rare missense genetic variants in several genes related to platelet functions and acetylsalicylic acid (ASA) response are associated with the platelet reactivity in patients with diabetes type 2 (T2D) on ASA therapy. Fifty eight exons and corresponding introns of eight selected genes, including PTGS1, PTGS2, TXBAS1, PTGIS, ADRA2A, ADRA2B, TXBA2R, and P2RY1 were re-sequenced in 230 DNA samples from T2D patients by using a pooled PCR amplification and next-generation sequencing by Illumina HiSeq2000. The observed non-synonymous variants were confirmed by individual genotyping of 384 DNA samples comprising of the individuals from the original discovery pools and additional verification cohort of 154 ASA-treated T2DM patients. The association between investigated phenotypes (ASA induced changes in platelets reactivity by PFA-100, VerifyNow and serum thromboxane B2 level [sTxB2]), and accumulation of rare missense variants (genetic burden) in investigated genes was tested using statistical collapsing tests. We identified a total of 35 exonic variants, including 3 common missense variants, 15 rare missense variants, and 17 synonymous variants in 8 investigated genes. The rare missense variants exhibited statistically significant difference in the accumulation pattern between a group of patients with increased and normal platelet reactivity based on PFA-100 assay. Our study suggests that genetic burden of the rare functional variants in eight genes may contribute to differences in the platelet reactivity measured with the PFA-100 assay in the T2DM patients treated with ASA.
DOI: 10.6084/m9.figshare.1610386.v1
title: Fly Song Playback Chambers

description: The 3D printer files are zipped and come with a description.
DOI: 10.6084/m9.figshare.1610410.v2
title: Copper and palladium complexes with substituted pyrimidine-2-thiones and 2-thiouracils: syntheses, spectral characterization, and X-ray crystallographic study

description: Copper(I) and palladium(II) complexes containing 5-acetyl-6-methyl-1,2,3,4-tetrahydropyrimidine-2-thione (L<sup>1</sup>), ethyl 4,6-dimethyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate (L<sup>2</sup>), <i>cis</i>-5-acetyl-6-ethyl-5,6-dihydro-2-thiouracil (L<sup>3</sup>), and 5,6-dihydro-2-thiouracil (L<sup>4</sup>) have been synthesized. All complexes were characterized by elemental analysis, IR, <sup>1</sup>H, and <sup>13</sup>C NMR spectroscopy. To assign bands in the IR spectra of L<sup>1</sup> and L<sup>2</sup> and complexes with Cu(I) and Pd(II), deuterium substitution of movable protons at N-atoms was used. The crystal structures of two compounds, [Cu(L<sup>2</sup>)<sub>2</sub>Cl] and [Pd(L<sup>4</sup>)<sub>2</sub>Cl<sub>2</sub>], were determined by X-ray single-crystal and powder diffraction, respectively. In [Cu(L<sup>2</sup>)<sub>2</sub>Cl], copper has a rare coordination number of three and triangular surrounding of two neutral L<sup>2</sup> molecules, coordinated through sulfurs, and chloride. In [Pd(L<sup>4</sup>)<sub>2</sub>Cl<sub>2</sub>], palladium has a standard square-planar geometry, formed by two uracil molecules and two chlorides. A new method for the synthesis of 5,6-dihydro-2-thiouracil, starting from β-aminopropionic acid, was suggested.
DOI: 10.6084/m9.figshare.1610063
title: The Harvard Organic Photovoltaics 2015 (HOPV) dataset: An experiment-theory calibration resource.

description: Standard data sets used for the calibration of computational results have been extremely useful for the development of electronic structure methods and their application to areas such as thermochemistry1–3 as well as non-covalent interactions4,5. To our knowledge, the field of organic photovoltaics, specifically as it pertains to high-throughput virtual screening, lacks a similar collection of data. Since the relationship between theoretically predicted and experimentally observed properties is often non-trivial, the dissemination of directly comparable data for a well-defined set of molecules can be a great asset to accelerate advances in this field. The Harvard Organic Photovoltaic Dataset (HOPV15) presented in this work is a collation of experimental photovoltaic data from the literature, and corresponding quantum-chemical calculations performed over a range of geometries, each with quantum chemical results using a variety of density functionals and basis sets. It is anticipated that this dataset will be of use in both relating electronic structure calculations to experimental observations through the generation of calibration schemes, as well as for the creation of new semi-empirical methods and the benchmarking of current and future model chemistries in the domain of organic electronics.
DOI: 10.6084/m9.figshare.1610215.v1
title: NCEP Australia

description: Data from NCEP for Australia saved as a Raster stack. Shared under the following license http://opendatacommons.org/licenses/odbl/1.0/ Work is attributted to Climatic Research Unit, University of East Anglia This dataset is used for demonstration in the zoon R package: https://zoonproject.wordpress.com/
DOI: 10.6084/m9.figshare.1610405
title: Next-generation re-sequencing of genes involved in increased platelet reactivity in diabetic patients on acetylsalicylic acid

description: The objective of this study was to investigate whether rare missense genetic variants in several genes related to platelet functions and acetylsalicylic acid (ASA) response are associated with the platelet reactivity in patients with diabetes type 2 (T2D) on ASA therapy. Fifty eight exons and corresponding introns of eight selected genes, including PTGS1, PTGS2, TXBAS1, PTGIS, ADRA2A, ADRA2B, TXBA2R, and P2RY1 were re-sequenced in 230 DNA samples from T2D patients by using a pooled PCR amplification and next-generation sequencing by Illumina HiSeq2000. The observed non-synonymous variants were confirmed by individual genotyping of 384 DNA samples comprising of the individuals from the original discovery pools and additional verification cohort of 154 ASA-treated T2DM patients. The association between investigated phenotypes (ASA induced changes in platelets reactivity by PFA-100, VerifyNow and serum thromboxane B2 level [sTxB2]), and accumulation of rare missense variants (genetic burden) in investigated genes was tested using statistical collapsing tests. We identified a total of 35 exonic variants, including 3 common missense variants, 15 rare missense variants, and 17 synonymous variants in 8 investigated genes. The rare missense variants exhibited statistically significant difference in the accumulation pattern between a group of patients with increased and normal platelet reactivity based on PFA-100 assay. Our study suggests that genetic burden of the rare functional variants in eight genes may contribute to differences in the platelet reactivity measured with the PFA-100 assay in the T2DM patients treated with ASA.
DOI: 10.6084/m9.figshare.1610405.v3
title: Next-generation re-sequencing of genes involved in increased platelet reactivity in diabetic patients on acetylsalicylic acid

description: The objective of this study was to investigate whether rare missense genetic variants in several genes related to platelet functions and acetylsalicylic acid (ASA) response are associated with the platelet reactivity in patients with diabetes type 2 (T2D) on ASA therapy. Fifty eight exons and corresponding introns of eight selected genes, including PTGS1, PTGS2, TXBAS1, PTGIS, ADRA2A, ADRA2B, TXBA2R, and P2RY1 were re-sequenced in 230 DNA samples from T2D patients by using a pooled PCR amplification and next-generation sequencing by Illumina HiSeq2000. The observed non-synonymous variants were confirmed by individual genotyping of 384 DNA samples comprising of the individuals from the original discovery pools and additional verification cohort of 154 ASA-treated T2DM patients. The association between investigated phenotypes (ASA induced changes in platelets reactivity by PFA-100, VerifyNow and serum thromboxane B2 level [sTxB2]), and accumulation of rare missense variants (genetic burden) in investigated genes was tested using statistical collapsing tests. We identified a total of 35 exonic variants, including 3 common missense variants, 15 rare missense variants, and 17 synonymous variants in 8 investigated genes. The rare missense variants exhibited statistically significant difference in the accumulation pattern between a group of patients with increased and normal platelet reactivity based on PFA-100 assay. Our study suggests that genetic burden of the rare functional variants in eight genes may contribute to differences in the platelet reactivity measured with the PFA-100 assay in the T2DM patients treated with ASA.
DOI: 10.6084/m9.figshare.1610054
title: Copy Number Variation Database

description: CNVs observed in population
DOI: 10.6084/m9.figshare.1609865
title: Cheetah camera trap data

description: Cheetah images from camera trap surveys in the Northern Tuli Game Reserve, Botswana
DOI: 10.6084/m9.figshare.1610405.v2
title: <b>Next-generation re-sequencing of genes involved in increased platelet reactivity in diabetic patients on acetylsalicylic acid</b>

description: The objective of this study was to investigate whether rare missense genetic variants in several genes related to platelet functions and acetylsalicylic acid (ASA) response are associated with the platelet reactivity in patients with diabetes type 2 (T2D) on ASA therapy. Fifty eight exons and corresponding introns of eight selected genes, including PTGS1, PTGS2, TXBAS1, PTGIS, ADRA2A, ADRA2B, TXBA2R, and P2RY1 were re-sequenced in 230 DNA samples from T2D patients by using a pooled PCR amplification and next-generation sequencing by Illumina HiSeq2000. The observed non-synonymous variants were confirmed by individual genotyping of 384 DNA samples comprising of the individuals from the original discovery pools and additional verification cohort of 154 ASA-treated T2DM patients. The association between investigated phenotypes (ASA induced changes in platelets reactivity by PFA-100, VerifyNow and serum thromboxane B2 level [sTxB2]), and accumulation of rare missense variants (genetic burden) in investigated genes was tested using statistical collapsing tests. We identified a total of 35 exonic variants, including 3 common missense variants, 15 rare missense variants, and 17 synonymous variants in 8 investigated genes. The rare missense variants exhibited statistically significant difference in the accumulation pattern between a group of patients with increased and normal platelet reactivity based on PFA-100 assay. Our study suggests that genetic burden of the rare functional variants in eight genes may contribute to differences in the platelet reactivity measured with the PFA-100 assay in the T2DM patients treated with ASA.
DOI: 10.6084/m9.figshare.1609803
title: The role of spatial boundaries in shaping long-term event representations: behavioural data

description: The excel file contains means for each participant and condition across Experiments 1-3.<br>
DOI: 10.6084/m9.figshare.1610054.v2
title: Copy Number Variation Database

description: CNVs observed in population
DOI: 10.6084/m9.figshare.1609800
title: ENSO and coastal development enhance coastal burial of terrestrial carbon

description: This file contains raw data associated with the following paper: Macreadie PI, Rolph T, Boyd R, Schröder-Adams C, Skilbeck CG (2015) ENSO and coastal development enhance coastal burial of terrestrial carbon. Plos One
DOI: 10.6084/m9.figshare.1610054.v1
title: Copy Number Variation Database

description: CNVs observed in population of patients with ID
DOI: 10.6084/m9.figshare.1609797
title: Lorem ipsum distribution

description: This is a dataset of the fictional species 'Lorem ipsum'. This species is new to the shores of the UK and is used to demonstrate the functionality of zoon, an R package for modelling species distributions.
DOI: 10.6084/m9.figshare.1609797.v1
title: Lorem ipsum distribution

description: This is a dataset of the fictional species 'Lorem ipsum'. This species is new to the shores of the UK and is used to demonstrate the functionality of zoon, an R package for modelling species distributions.
DOI: 10.6084/m9.figshare.1609800.v1
title: ENSO and coastal development enhance coastal burial of terrestrial carbon

description: This file contains raw data associated with the following paper: Macreadie PI, Rolph T, Boyd R, Schröder-Adams C, Skilbeck CG (2015) ENSO and coastal development enhance coastal burial of terrestrial carbon. Plos One
DOI: 10.6084/m9.figshare.1609804
title: The role of spatial boundaries in shaping long-term event representations: computational model

description: MATLAB code for model presented in paper.
DOI: 10.6084/m9.figshare.1609803.v3
title: The role of spatial boundaries in shaping long-term event representations: behavioural data

description: The excel file contains means for each participant and condition across Experiments 1-3.<br>
DOI: 10.6084/m9.figshare.1609792
title: An SNP in Exon 11 of Chicken 5′-AMP-Activated Protein Kinase Gamma 3 Subunit Gene was Associated with Meat Water Holding Capacity

description: The 5′-Adenosine-monophosphate -activated protein kinase plays a key role in regulating cellular energy homeostasis, and it was reported that nucleotide variants in the genes coding the protein were associated with meat quality. In the present study, genetic variations in the exons of gamma non-catalytic subunit genes of the protein kinase were screened among 284 White Plymouth Rock chickens from 7 families with denaturing gradient gel electrophoresis, and their meat quality traits including drip loss and cooked meat rate which reflect water holding capacity and serum biochemical indices were also measured, and the association between the genotypes and the traits was analyzed with a SAS GLM procedure. Our results showed that there were three G/A nucleotide variants including one in exon 6 of the gamma subunit 2 gene and two in exon 11 of the gamma subunit 3 gene, which resulted in amino acid substitutions V150I, V315 M, and A337 T, respectively. And locus V315 M was associated with water holding capacity significantly (P
DOI: 10.6084/m9.figshare.1609803.v2
title: The role of spatial boundaries in shaping long-term event representations: behavioural data

description: The excel file contains means for each participant and condition across Experiments 1-3.<br>Note, these was a mistake with the Control analyses of Experiments 2 & 3 in the "Horneretal_Rooms_2015" file. The file "Horneretal_Rooms_2016" contains the correct data that is reported in the paper.
DOI: 10.6084/m9.figshare.1609792.v1
title: An SNP in Exon 11 of Chicken 5′-AMP-Activated Protein Kinase Gamma 3 Subunit Gene was Associated with Meat Water Holding Capacity

description: The 5′-Adenosine-monophosphate -activated protein kinase plays a key role in regulating cellular energy homeostasis, and it was reported that nucleotide variants in the genes coding the protein were associated with meat quality. In the present study, genetic variations in the exons of gamma non-catalytic subunit genes of the protein kinase were screened among 284 White Plymouth Rock chickens from 7 families with denaturing gradient gel electrophoresis, and their meat quality traits including drip loss and cooked meat rate which reflect water holding capacity and serum biochemical indices were also measured, and the association between the genotypes and the traits was analyzed with a SAS GLM procedure. Our results showed that there were three G/A nucleotide variants including one in exon 6 of the gamma subunit 2 gene and two in exon 11 of the gamma subunit 3 gene, which resulted in amino acid substitutions V150I, V315 M, and A337 T, respectively. And locus V315 M was associated with water holding capacity significantly (P
DOI: 10.6084/m9.figshare.1609784
title: How to conduct a Social Network Analysis: a tool for empowering teams and work groups

description: Anglim, J., & Waters, L. (2007). How to conduct a social network analysis: A tool for empowering teams and work groups. Workshop presented at 7thAustralian Industrial & Organisational Psychology Conference, June 28-30, Adelaide, Australia.
DOI: 10.6084/m9.figshare.1609779
title: “I Feel Contaminated in my Fake Hand”: Obsessive-Compulsive-Disorder like Disgust Sensations Arise from Dummy during Rubber Hand Illusion

description: Data for the publcation: “I Feel Contaminated in my Fake Hand”: Obsessive-Compulsive-Disorder like Disgust Sensations Arise from Dummy during Rubber Hand Illusion
DOI: 10.6084/m9.figshare.1609777
title: Open pledge

description: Text form of the pledge I made publicly at OpenCon 2015 to be open with my work as a researcher. This is a revised form of my pledge, orginally made at the 2014 SPARC Open Access Meeting (see http://dx.doi.org/10.6084/m9.figshare.954994).
DOI: 10.6084/m9.figshare.1609779.v3
title: “I Feel Contaminated in my Fake Hand”: Obsessive-Compulsive-Disorder like Disgust Sensations Arise from Dummy during Rubber Hand Illusion

description: Data for the publcation: “I Feel Contaminated in my Fake Hand”: Obsessive-Compulsive-Disorder like Disgust Sensations Arise from Dummy during Rubber Hand Illusion
DOI: 10.6084/m9.figshare.1609770.v1
title: Trial

description: Trial
DOI: 10.6084/m9.figshare.1609777.v1
title: Open pledge

description: Text form of the pledge I made publicly at OpenCon 2015 to be open with my work as a researcher.
DOI: 10.6084/m9.figshare.1609779.v2
title: “I Feel Contaminated in my Fake Hand”: Obsessive-Compulsive-Disorder like Disgust Sensations Arise from Dummy during Rubber Hand Illusion

description: Data for the publcation: “I Feel Contaminated in my Fake Hand”: Obsessive-Compulsive-Disorder like Disgust Sensations Arise from Dummy during Rubber Hand Illusion
DOI: 10.6084/m9.figshare.1609757
title: Evaluation of the Pulmonary Toxicity of Ambient Particulate Matter From Camp Victory, Iraq

description: Anecdotal reports in the press and epidemiological studies suggest that deployment to Iraq and Afghanistan may be associated with respiratory diseases and symptoms in U.S. military personnel and veterans. Exposures during military operations were complex, but virtually all service members were exposed to high levels of respirable, geogenic dust. Inhalation of other dusts has been shown to be associated with adverse health effects, but the pulmonary toxicity of ambient dust from Iraq has not been previously studied. The relative toxicity of Camp Victory dust was evaluated by comparing it to particulate matter from northern Kuwait, a standard U.S. urban dust, and crystalline silica using a single intratracheal instillation in rats. Lung histology, protein levels, and cell counts were evaluated in the bronchoalveolar lavage fluid 1–150 d later. The Iraq dust provoked an early significant, acute inflammatory response. However, the level of inflammation in response to the Iraq dust, U.S. urban dust, and Kuwait dust rapidly declined and was nearly at control levels by the end of the study At later times, animals exposed to the Iraq, U.S. urban, or Kuwait dusts showed increased small airway remodeling and emphysema compared to silica-exposed and control animals without evidence of fibrosis or premalignant changes. The severity and persistence of pulmonary toxicity of these three dusts from the Middle East resemble those of a U.S. urban dust and are less than those of silica. Therefore, Iraq dust exposure is not highly toxic, but similar to other poorly soluble low-toxicity dusts.
DOI: 10.6084/m9.figshare.1609757.v1
title: Evaluation of the Pulmonary Toxicity of Ambient Particulate Matter From Camp Victory, Iraq

description: Anecdotal reports in the press and epidemiological studies suggest that deployment to Iraq and Afghanistan may be associated with respiratory diseases and symptoms in U.S. military personnel and veterans. Exposures during military operations were complex, but virtually all service members were exposed to high levels of respirable, geogenic dust. Inhalation of other dusts has been shown to be associated with adverse health effects, but the pulmonary toxicity of ambient dust from Iraq has not been previously studied. The relative toxicity of Camp Victory dust was evaluated by comparing it to particulate matter from northern Kuwait, a standard U.S. urban dust, and crystalline silica using a single intratracheal instillation in rats. Lung histology, protein levels, and cell counts were evaluated in the bronchoalveolar lavage fluid 1–150 d later. The Iraq dust provoked an early significant, acute inflammatory response. However, the level of inflammation in response to the Iraq dust, U.S. urban dust, and Kuwait dust rapidly declined and was nearly at control levels by the end of the study At later times, animals exposed to the Iraq, U.S. urban, or Kuwait dusts showed increased small airway remodeling and emphysema compared to silica-exposed and control animals without evidence of fibrosis or premalignant changes. The severity and persistence of pulmonary toxicity of these three dusts from the Middle East resemble those of a U.S. urban dust and are less than those of silica. Therefore, Iraq dust exposure is not highly toxic, but similar to other poorly soluble low-toxicity dusts.
DOI: 10.6084/m9.figshare.1609777.v2
title: Open pledge

description: Text form of the pledge I made publicly at OpenCon 2015 to be open with my work as a researcher.