cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.14457/cu.the.2007.1612
title: Utilization of fly ash from biomass power plant in lightweight concrete

description: The purpose of this research is to study and develop lightweight concrete using waste products; namely, rice husk ash and biomass fly ash. The wastes were obtained from a biomass power plant as replacement materials for main ingredient, Portland cement, to make lightweight concrete. Experimental programs involve determination of proper manufacturing method of autoclaved aerated lightweight concrete using blowing agent and duration of curing time based on density and compressive strength of lightweight concrete. Optimum amount of aluminium powder and water-to-binder ratio were investigated for all mixes throughout the experimental programs. Physical and chemical characteristics of biomass fly ash were also determined. The physical and mechanical properties of lightweight concrete samples evaluated include dry density, compressive strength, and water absorption. The testing results showed that the optimum duration of high pressure curing was 14 hours. While the optimal amount of aluminium content, water–to-binder ratio, and binder-to-aggregate ratio of lightweight concrete were 0.3% of aluminium powder by total solid weight, 0.472, and 55:45, respectively. The use of fly ash as the main ingredient to replace Portland cement resulted in decrease in density significantly. From main testing results, it can be used to noted that the optimal mix proportion be 30%RH, 30%B3 which used the highest amount of biomass fly ash replacement and did not compromise the aerated lightweight mortar properties as compared with control mix.. Finally, it can be concluded that fly ash from a biomass power plant can be sufficiently used as cement replacement for lightweight concrete block production. Beside the utilization of the wastes, biomass fly ash, pollution, and disposal problems can also be mitigated as a result.
DOI: 10.14457/cu.the.2007.1613
title: Surface modification of fabrics by air plasma and argon plasma generated from theta-pinch device

description: Polyester, cotton and polyester/cotton blended (T/C) fabrics were surfaced-modified by high temperature-pulsed air plasma and argon plasma generated from a theta-pinch device. The number of plasma shot applied to the fabric was varied from 10, 20, 30 and 40 shots. The theta-pinch device was operated with the pressure of 2 Pa, the maximum input current of 125 kA and the charging voltage of 20 kV. Attenuated total reflectance fourier transform infrared spectra of all plasma-treated fabrics indicated the formation of hydrophilic functional groups such as carbonyl, amine and aldehyde groups depending on the gas type and the fabric type. In addition, scanning electron microscopic photographs revealed the etching and the redeposition of etched fragments on the fabric surface resulting in surface roughness. It was found that better wettability was achieved with increasing the number of plasma shot. However, dyeability and colorfastness to washing properties were also depended on the fabric type. It was found that highly hydrophilic fabric such as cotton, air and argon plasma treatments had no effects on these two properties. In the case of polyester and T/C fabrics, after dyeing with selected dyes, it was found that the highest color strengths were achieved when they were modified by 20 shots of air plasma.
DOI: 10.14457/cu.the.2007.1614
title: Control structure design of reaction section of hydrodealkylation process using maximum scaled gain method

description: Design a process control structure for a complex process, such as the process having material or energy recycle, is a complicate task. The design control loop would effect the operation significantly. This thesis presents a plantwide control design procedure base on basic idea of self-optimizing control to select controlled variables which when kept constant lead to minimum economic loss. The maximum scaled gain is used to selecting and paring controlled variables with manipulated variables. This presented-method is elementary and effective. In the study, three control structures were designed and compared. In order to illustrate the dynamic behaviors of the control structures in reaction section of HDA plant when economic disturbance load occur such as change in toluene flowrates, methane composition in fresh gas feed and disturbance load hot stream were made. All of control structures can operate to achieve the objective and within process constraints. The performance of designed control structures were presented in IAE value and compared with reference structure. The designed structures are faster response than reference structure. The benzene products of designed structures (6.25%) are smaller deviation from steady state than reference structure (6.85%). Thence, the designed structures were studied about variation of heat exchanger duty to cost and dynamic performance of structure. Disturbance load cold stream, disturbance load hot stream and fresh toluene feed flowrates were made for study dynamic response. The large heat exchanger is lower utility cost than the small heat exchanger. The good structure can handle disturbance of large heat exchanger which small furnace duty
DOI: 10.14457/cu.the.2007.1615
title: Inter-population linkage disequilibrium patterns of GABRA2 and GABRG1 genes at the GABA locus on human chromosome 4

description: GABRA2 and GABRG1, which encode the α2 and γ1 subunits, respectively, of the GABAA receptor, are located in a cluster on chromosome 4p. The GABRA2 locus has been found to be associated with alcohol dependence (AD) in several studies, but no functional variant that can account for this association has been identified. In order to understand the reported associations, we sought to understand LD patterns and haplotype structure of these genes. With close intergenic distance, ~90 kb, it was anticipated some markers might show intergenic LD. Variation in 13-SNP haplotype block structure was observed in 5 different populations: European American, African American, Chinese [Han and Thai], Thai, and Hmong. In Hmong, a 280 kb region of considerably higher LD spans the intergenic region, whereas in other populations, there were two or more LD blocks cross this region. To understand better the findings of association of AD with markers located at the 3’ region of GABRA2 which may be attributable to the adjacent gene, GABRG1, we genotyped Six tag single nucleotide polymorphisms (SNPs) that span GABRG1 and GABRA2 in 276 African-Americans (AAs) with AD and in 242 AA controls. Individual single SNP associations were tested by chi-square. Nominally significant allele frequency differences were identified for rs10938426, at GABRG1 intron 1, with p= 0.044. Significant differences in both genotype and allele frequency (p=0.008 and 0.007 respectively) were observed at rs279869, located at GABRA2 intron 6. We performed haplotype association analysis by means of PHASE. Six-SNP haplotypes combining SNPs from both gene loci showed differences between controls and AD subjects, p=0.0027, significant after Bonferroni correction. Two-SNP haplotype composed of rs10938426 and rs279869, showed greater significance (p=0.00013). This finding suggests significance of the interrelationship between these two genes and the possibility of risk loci in each of them. A two-SNP haplotype composed of one SNP from each gene suggests possible interaction of these genes and supports the involvement of both in predisposition to AD in AAs.
DOI: 10.7910/dvn/hsrilh/ne02fp
title: ai_public_opinion_us_2018_report_dataverse.Rmd

description: :unav
DOI: 10.7910/dvn/hsrilh/xjpaoq
title: YALE0065_field-date.tab

description: :unav
DOI: 10.14457/cu.the.2007.1616
title: Qualitative and quantitative determinations of anticonvulsants in centella asiatica (L.) urban

description: Ethyl acetate extract of the aerial part of Centella asiatica (L.) Urban (CA) was found to possess the anticonvulsant activity in the PTZ test model. Using the fractionation of the extract by conventional chromatographic technique together with the standard PTZ antiepileptic screening model, it was found that saturated very long-chain fatty acids (VLFAs) were the active principle in CA. Spectroscopic techniques were used to elucidate the chemical structure, IR and NMR data confirmed that active principle are VLFAs with the GC-MS technique to analyze the composition of the VLFAs, revealed that the sample contain C12-C28 chain length acids, which contain C16 and C28 chain length acids as main component. A thin-layer chromatographic (TLC) method was developed to determine VLFAs by using silica gel plate GF254 as stationary phase and hexane: ethyl acetate: glacial acetic acid (14:6:1) as developing solvent, oleanolic acid as internal standard. The detection of the TLC spot was developed by spraying with 3% phosphomolybdic acid in methanol and scanned with densitometer at wavelength 550 nm. This method was validated according to ICH guideline. The percentage recovery was in the range of 98.68-102.99 and percentage of RSD was not more than 2. The developed method was applied to analyze the CA that collected from 12 locations of Thailand, such as Prachin Buri, Nakhon Si Thammarat (Ban Bo Lo local growth and Ban Bo Lo trade), Ubon Ratchathani, Trat, Rayong, Chon Buri, Nakhon Ratchasima, Sukhothai, Chiang Mai (green petioles), Chiang Mai and Phitsanulok. The maximum content of VLFAs was founded 0.27% w/w (Rayong), 0.24% w/w (Sukhothai and Nakhon Ratchasima). Furthermore, the content of those compounds in CA that collected from the commercial crops of Nakhon Pathom, Ubon Ratchathani and Nakhon Si Thammarat provinces. The maximum VLFAs of CA in sample collected from Nakhon Pathom province was observed also annually determine in November, from Ubon Ratchathani in September and from Nakhon Si Thammarat province was observed in May. Information obtained may be utilized as criteria for plant varieties selection and breeding programs for commercial cultivars of optimal VLFAs content for further isolation of pure VLFAs.
DOI: 10.14457/cu.the.2007.1617
title: Formulation development of film coated tablets containing malvastrum coromandelianum extract

description: The spray-dried powder of Malvastrum coromandelianum water extract has been reported to be able to lower blood sugar for diabetic rabbits. It was also utilized for treating diabetic patients. However, the dried powder turned from pale brown into damp dark brown mass after storage for a few days, even filled into hard gelatin capsule. Therefore, the purpose of this study was to develop film coated tablets of high dose of Malvastrum coromandelianum powder. The spray-dried powder was evaluated for particle size, flow, and density. The core tablets were produced on a single-punch tablet press by direct compression method and using various fillers and lubricants to obtain optimal core tablet formulation. The coating process was performed using hydroxypropylmethylcellulose (HPMC), chitosan and Eudragit E100 as film former by Thai coater. These tablets were evaluated for friability, hardness, disintegration and % drug dissolved at 60 minutes. The content was analyzed by high performance liquid chromatography. The influences of type of polymeric films HPMC, chitosan and Eudragit E100 on adhesive strength and moisture protection were evaluated both initially and accelerated conditioned (45 ± 2 ℃ /75 ± 5 % RH for 4 months). The results found Malvastrum coromandelianum spray-dried powder exhibited poor flow property in spite of narrow sizes and spherical shape particles with rough surface and aggregation in cluster. The selected core tablets showed satisfactory properties, having light brown color with smooth and shiny surface. HPMC and Eudragit E100 film coated tablets showed good appearance and physical properties of high mechanical resistance with low moisture sorption. The chitosan coated tablets exhibited the highest moisture sorption and color change. The concentration film coated significantly influenced both moisture and dissolution pattern while the type of polymer had slight effect on disintegration time. After storage at accelerated condition, the content of both HPMC and Eudragit E100 coated tablets was still within the standard of pharmacopoeia and good appearance. The percent remaining of the active compounds was 90.41% and 90.65% of the initial content as HPMC5 and PMC2, respectively. However, HPMC coated tablets showed poor appearance of swelling after storage for 6 months. In conclusion, Eudragit E100 film coated tablets of high dose of Malvastrum coromandelianum extract could be prepared with satisfactory properties and stability.
DOI: 10.14457/cu.the.2007.1618
title: Alphaglucosidase inhibitors from Gynura procumbens

description: Glucosidase is the key enzyme which catalyzes the final step in the digestive process of carbohydrates. Hence, -glucosidase inhibitors can retard the liberation of D-glucose from complex dietary carbohydrates and delay glucose absorption, reducing plasma glucose levels. In a preliminary examination of the extracts of Gynura procumbens, the aqueous extract exhibited highest inhibitory activity on ?-glucosidase. Further fractionation of the active aqueous extract by bioassay guidance furnished fractions showing 82.93, 59.41, and 64.21% inhibition on ?-glucosidase at concentration 1mg/ml, respectively. Moreover, a kinetic study was performed on the most active fraction to analyse the inhibition mechanism. The active fractions were treated with acetic anhydride to give 3 acetyl derivatives, GP1, GP2, and GP3, respectively. The structures were determinated by analyses of 1H, 13C and 2D-NMR, IR and mass spectrometry. The results suggested that the present components were [alpha]-D-glucosyl-(1 [vector] 2)-O-psicoside, [alpha]-D-glucosyl-(1 [vector] 2)-O-fructoside and [alpha]-D-galactosyl-(1 [vector] 2)-O-tagatoside, respectively.
DOI: 10.14457/cu.the.2007.1619
title: Viscoelastic and swelling properties of acrylamide copolymeric hydrogels

description: The viscoelastic and swelling properties of polyacrylamide-based hydrogels containing ionic moiety were investigated as a function of anionic comonomer structure. The hydrogels were synthesized from free-radical crosslinking copolymerization of acrylamide and ionic comonomer; i.e. monoprotic acid: acrylic acid, crotonic acid and diprotic acid: maleic acid, itaconic acid. Initiation by a redox initiator of ammonium persulfate (APS) and N,N,N',N'– tetramethylethylenediamine (TEMED). The N,N'-methylenebisacrylamide (MBA) crosslinking agent was used in the copolymerization. The copolymerization was carried out at 250 rpm, 45 degrees celsius under nitrogen atmosphere for 30 minutes. Feeding composition of all components, i.e. monomer, comonomer, initiator, co-initiator, and crosslinker was fixed to the same value for all copolymeric systems. The synthesized polymers were characterized by RAMAN Spectroscopy and Scanning Electron Microscopy. The mechanical strength of the swollen hydrogels was measured by a rheological method. The copolymers have a higher storage modulus ([storate modulus]) which agrees with the lower water absorption. The average molecular weight between crosslinks ([average molecular weight between crosslinks]) and polymer-solvent interaction parameter ([interaction parameter of polymer with solvent]) was determined from swelling data using equations based on Flory-Rehner swelling theory, and the approaches of Brannon-Peppas and Peppas on monoprotic acid-containing hydrogels. The equation modified by Şen and Güven was used for determining M[subscript c] and chi for diprotic acid-containing hydrogels. Equilibrium elastic modulus was used to determine M[subscript c] based on the polymer network theory. Large difference between [average molecular weight between crosslinks] from both measurements was observed. This difference on the basis of different theories indicates an existence of an intrinsic heterogeneous structure within the hydrogels.
DOI: 10.14457/cu.the.2007.1620
title: Enhancement of tetrachloroethylene removal efficiency by using extended surfactants

description: This research aims to introduce seven extended anionic surfactants, Alfoterra series, to enhance the tetrachloroethylene (PCE) removal from contaminated sand, and to investigate the optimum condition of different extended surfactants and electrolyte concentrations that yields the highest PCE removal. Alfoterra surfactants varying alkyl chain length and number of propylene oxide (PO) group in their molecules were used and mixed with sodium dihexyl sulfosuccinate (AMA), anionic surfactant, to form microemulsion solutions with PCE. This study hypothesized that the optimum condition to maximize the solubilization of PCE in micelles occurs at the supersolubilization region in the type I microemulsion. The supersolubilization condition for microemulsion of each Alfoterra mixed with AMA was obtained by measuring interfacial tension incorporated with an observation of an aqueous phase appearance. The critical micelle concentrations (CMC) of mixed Alfoterra surfactants with AMA were determined and found that the longer the Alfoterra chain length or the higher the number of PO group, the lower the CMC. The solubilization study of the seven systems of Alfoterra mixed with AMA was carried out in batch experiments. The results showed that the longer the chain length or the higher the number of PO groups in Alfoterra gives the higher micelle-water partitioning coefficient (Km) indicating that the PCE solubilization is higher. However, the effects of both factors are not linearly correlated, especially for the very long alkyl chain length, the PCE solubilization is remarkably reduced. From the solubilization study result, the three surfactant systems were selected for column study based on the solubilization capacity for PCE as low, medium, and high namely; C[subscript 12,13]H[subscript 25,27]-(PO)[subscript 4]–SO[subscript 4]Na+AMA, C[subscript 14,15]H[subscript 29,31]-(PO)[subscript 4]–SO4Na+AMA and C[subscript 14,15]H[subscript 29,31]-(PO)[subscript 8]–SO[subscript 4]Na+AMA, respectively. The total removal of PCE in the column using three surfactant systems was illustrated and the removal mechanism was distinguished as mobilization and solubilization. The results revealed that PCE can be removed from contaminated sand in the range of 59-83%. As expected, the system of C[subscript 14,15]H[subscript 29,31]-(PO)[subscript 8]–SO[subscript 4]Na+AMA, which yields the highest solubilization in batch experiments, gives the highest PCE removal by solubilization mechanism.
DOI: 10.14457/cu.the.2007.1621
title: Learning binary variables selections to improve the mip solution time in architectural layout design optimization

description: Varieties of optimization techniques have been used to solve an architectural layout design optimization for more than a decade such as an expert system, an evolutionary algorithm, a simulated annealing and a mathematical programming method. This thesis will concentrate on the mathematical programming technique that formulates an architectural layout design optimization as the architectural layout Mixed Integer Programming (MIP) model called AL-MIP. All non-linear relationship among design components will be captured using the corresponding linear equalities and linear inequalities. Due to the combinatorial nature of the MIP solutions, the AL-MIP can be solved optimally for a small size, (2-5 rooms), within a reasonable time limit. To remedy this situation, both valid inequality constraints called AL-MIP+ from non-circular connectivity of consecutive room connections and the architect’s preference constraints have been adopted that reduces the computational time significantly. Moreover, to speed up the computational time of AL-MIP+, the machine learning using Genetic Algorithm (GA) has been applied to determine the best sequences of branching variables, the Special Order Set (SOS) called AL-MIP+GA. The search space reduction comes from the better candidate solution used to prune the search tree. These combinations of speeding up technique illustrate the computational MIP iterations and time reduction more than 80% that is now achievable for a medium size (5-10 rooms). The global solutions from 10 room patterns have been solved within a few minute. Indeed, both valid inequality MIP and learning methodology present a novel mathematical concept to optimize MIP for an architectural layout design problem.
DOI: 10.14457/cu.the.2007.1622
title: The study of neural potential in mesenchymal stem cells

description: Mesenchymal stem cell (MSC) is tissue-specific stem cells that can differentiat into bone cartilage, chrodocyte, adipocyte, and myoblast. Recently, there have been many reports that MSC have a capacity to differentiate into cells in other cell lineage, so called transdifferentiation, such as neural cells. Using either stem cell-based therapy or creating trophic factor is benefit for treatment of neural injury because the rebuilding neuron is an inefficient process in nature. Thus, understanding on this mechanism will lead to an improvement of MSCs future application, while fibroblast growth factor 2 (FGF2) and retinoic acid (RA) are commonly used to induce neural differentiation of MSCs. Our results proposed that the mechanism neural gene regulation is associated with repressor element 1 (RE 1)-silencing transcription factor (REST) also called neuron-restrictive silencer factor (NRSF), REST/NRSF and NRSE dsRNA, found specifically in mouse MSCs which only found in neural tissue. NRSE dsRNA levels were up-regulated when mouse MSCs were treated with RA. In this study we found the basic understanding that will lead to improve the neural differentiation method of MSCs for future application.