cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.9761558.v1
title: Supplementary Material for: Outcomes of Prophylactic Pantoprazole in Adult Intensive Care Unit Patients Receiving Dialysis: Results of a Randomized Trial

description: <b><i>Background:</i></b> Intensive care unit (ICU) patients with acute kidney injury requiring renal replacement therapy (RRT) are considered at high risk of gastrointestinal (GI) bleeding and stress ulcer prophylaxis (SUP) is often prescribed. We aimed to assess the incidence of GI bleeding and effects of SUP in these patients. <b><i>Methods:</i></b> We assessed GI bleeding in ICU patients receiving RRT at baseline (and at any time in the ICU) and effects of prophylactic pantoprazole versus placebo in the international SUP in the ICU (SUP-ICU) trial. All analyses were conducted according to a published protocol and statistical analysis plan. <b><i>Results:</i></b> Data of 3,291 acutely admitted adult ICU patients with one or more risk factors for GI bleeding randomized to pantoprazole or placebo intravenously once daily during ICU stay (until ICU discharge, death, or a maximum of 90 days) were analyzed. Some 20 out of 258 (7.8%, 95% CI 4.5–11.1%) and 52 out of 568 (9.2%, 95% CI 6.8–11.6%) of the patients receiving RRT at baseline and at any time in ICU, respectively, developed clinically important GI bleeding in the ICU. We did not observe statistically significant differences in the intervention effect (pantoprazole vs. placebo) in the proportion of patients with clinically important GI bleeding, clinically important events, infectious adverse events, use of interventions to stop GI bleeding, or 90-day mortality in patients with versus without RRT at baseline. <b><i>Conclusions:</i></b> In adult ICU patients receiving RRT at baseline, we observed high incidences of clinically important GI bleeding, but did not observe effects of pantoprazole versus placebo in this subgroup.
DOI: 10.6084/m9.figshare.22331191.v1
title: Suplemental file S1. PROC MIXED and LSMESTIMATE Code for SAS

description: Example of the code used to account for statistical significances for phenotype and other variables.
DOI: 10.6084/m9.figshare.1222998.v1
title: Data Sharing Effect on Article Citation Rate in Paleoceanography

description: The validation of scientific results requires reproducible methods and data. Often, however, data sets supporting research articles are not openly accessible and interlinked. This analysis tests whether open sharing and linking of supporting data through the PANGAEA® data library measurably increases the citation rate of articles published between 1993 and 2010 in the journal Paleoceanography as reported in the Thomson Reuters Web of Science database. The 12.85% (171) of articles with publicly available supporting data sets received 19.94% (8,056) of the aggregate citations (40,409). Publicly available data were thus significantly (p=0.007, 95% confidence interval) associated with about 35% more citations per article than the average of all articles sampled over the 18-year study period (1,331), and the increase is fairly consistent over time (14 of 18 years). This relationship between openly available, curated data and increased citation rate may incentivize researchers to share their data.
DOI: 10.6084/m9.figshare.19535572.v1
title: Supplementary Material for: Nontraditional Risk Factors for Residual Recurrence Risk in Patients with Ischemic Stroke of Different Etiologies

description: <b><i>Background and Objective:</i></b> With the popularization of guideline-based secondary prevention based on traditional risk factors, rates of stroke recurrence reduced greatly after ischemic stroke (IS) or transient ischemic attack (TIA), but the residual risk still exists. We aim to evaluate which IS subtype benefits the most from the current secondary prevention and to evaluate nontraditional risk factors for residual recurrence risk of different IS etiologies. <b><i>Methods:</i></b> The study included IS/TIA patients who participated in both biomarker substudy and imaging substudy of the Third China National Stroke Registry. We used 5 guideline-recommended interventions (antiplatelet, statins, anticoagulant, antihypertensive, and antidiabetic therapies) to document the performance of secondary prevention care. Residual risk was defined as the risk of stroke recurrence despite adherence to these 5 guideline-based secondary prevention strategies. Risk factors associated with stroke recurrence were analyzed by using Cox regression models. <b><i>Results:</i></b> In total, 9,733 patients were included in this study. At 3 months, 4,186 (43.0%) patients adhered to 5 secondary prevention strategies, and the residual risk of recurrence was 5.1%. According to Trial of Org 10172 in Acute Stroke Treatment subtypes, cardioembolism benefited the most from current secondary prevention (relative risk reduction: 65.2%), followed by large-artery atherosclerosis (LAA) (29.0%) and small-artery occlusion (SAO) (20.0%). Despite adhering to secondary prevention strategies, high sensitivity C-reactive protein, interleukin-6 (IL-6) levels, and impaired renal function were independent risk factors for the residual recurrence risk of LAA subtype, while IL-6 and trimethylamine N-oxide significantly contributed to the residual risk of SAO subtype. <b><i>Conclusions:</i></b> LAA and SAO subtypes own the specific nontraditional risk factors while inflammation is a common risk factor for residual recurrence risk of both.
DOI: 10.6084/m9.figshare.19771999.v1
title: Supplementary Material for: Low-Dose Alcohol-Induced Inhibition of Mouse Orthotopically Transplanted Tumors Is Associated with T-Cell Response

description: <b><i>Introduction:</i></b> The effects of low-dose alcohol consumption on colorectal cancer development are not well understood. Epidemiological studies have reported that people who consume small amounts of alcohol have lower mortality rates than both nondrinkers and heavy drinkers. This phenomenon has been labeled the “J-curve effect” of alcohol. This study examined the effects of low-dose alcohol (0.5%, 1%, and 2%) on tumor growth in a transplant colon cancer model. <b><i>Methods:</i></b> BALB/c and BALB/c nude mice were used to analyze T-cell immunity. Syngeneic CT26 murine colon cancer cells were implanted into the cecal wall, and the resulting T-cell immune effects were monitored. <b><i>Results:</i></b> The growth of orthotopic tumors was markedly inhibited upon ingestion of low-dose (0.5%) alcohol compared with that in the control mice. In contrast, cells from the same line were injected into the cecal wall of nude mice, and tumor growth inhibition was not observed. Histopathological and RNA sequence analyses were performed to elucidate the mechanisms underlying tumor growth inhibition. An increase in tumor CD8<sup>+</sup> T lymphocytes and changes in cytokine levels were observed. Microbiome analysis using 16S rRNA gene sequencing of cecal contents was performed and revealed <i>Mucispirillum schaedleri</i> and <i>Clostridium cocleatum</i> showed decreased and increased abundance, respectively, in the alcohol group. <b><i>Discussion/Conclusion:</i></b> Ingesting a threshold amount of alcohol results in the infiltration of T lymphocytes, which may enhance immune responsiveness in mouse colorectal cancer models.
DOI: 10.6084/m9.figshare.28640471.v1
title: Figure 2. ARPES and DFT calculations

description: Figure 2. ARPES and DFT calculations
DOI: 10.6084/m9.figshare.24942420.v1
title: TEM and FF Cryo-SEM images of Arabidopsis plant

description: Ultrastructural and supramolecular rearrangements that occur during the dark-to-light transition in plants.
DOI: 10.17632/bk57yxws9v
title: Muc25 raw data

description: Raw data of Muc25 submitted for Virulence
DOI: 10.17632/bvv4hk4dzc
title: LINF_170012500

description: Acyl-CoA binding protein | ACBP_103; Leishmania infantum (strain JPCM5)
DOI: 10.6084/m9.figshare.11493420.v1
title: data_and_code_for_Mobike_v4.zip

description: The dataset and sourcecode for shared bike paper.
DOI: 10.6084/m9.figshare.16832260.v1
title: Supplementary Material for: Risk Stratification as a Predictive Factor for Cephalosporin Allergy: A Case-Controlled Study

description: <b><i>Background:</i></b> Compared to penicillin, cephalosporin allergies are less common in children, and their diagnostic approach is less standardized. A recent European Academy of Allergy and Clinical Immunology position paper provided a risk stratification system for patients with suspected β-lactam hypersensitivity reactions. <b><i>Objective:</i></b> This study aimed to evaluate risk stratification and predicting factors for confirmed cephalosporin hypersensitivity. <b><i>Methods:</i></b> The case-controlled study included patients with confirmed cephalosporin hypersensitivity (skin tests, <i>n</i> = 53; drug provocation, <i>n</i> = 19). For each patient, 2 age- and gender-matched control subjects were included in the study. Data were retrieved from patients’ records and analyzed retrospectively. Risk stratification was performed according to the severity of index reactions, which was initially divided as high and low risk and then further divided as immediate and nonimmediate. <b><i>Results:</i></b> According to risk stratification, the patient and control groups were divided as follows: high-risk immediate (66.7% vs. 13%, respectively), high-risk delayed (1.4% vs. 8.3%, respectively), low-risk immediate (16.7% vs. 16%, respectively), and low-risk delayed (15.3% vs. 62.9%, respectively). Immediate reactions (odds ratio [OR]: 12.1, 95% confidence interval [CI]: 9–24.8, <i>p</i> &lt; 0.001) and high-risk reactions (OR: 7.8, 95% CI: 4.1–14.6, <i>p</i> &lt; 0.001) were associated with confirmed cephalosporin hypersensitivity in univariate analysis. Multivariate regression analysis indicated that immediate reactions (OR: 7.5, 95% CI: 3.3–16.8, <i>p</i> &lt; 0.001) and high-risk reactions (OR: 5.2, 95% CI: 2.1–12.9, <i>p</i> &lt; 0.001) were significant risk factors for the prediction of cephalosporin hypersensitivity. <b><i>Conclusion:</i></b> This model can be applied in children with suspected cephalosporin allergy. Skin testing provides diagnostic information in high-risk patients with immediate reactions and reduces the need for drug provocation testing in these patients. It is highly likely to confirm the diagnosis of low-risk patients directly with provocation tests without skin tests. High-risk and immediate reactions were found to be predictive factors for confirmed cephalosporin allergy.
DOI: 10.6084/m9.figshare.25289353.v1
title: Datasets used in EMFSA

description: The datasets used in paper "EMFSA: emoji-based multifeature fusion sentiment analysis", proposing EMFSA model
DOI: 10.6084/m9.figshare.25707115.v2
title: R script for model specification from Sleep in the wild: the importance of individual effects and environmental conditions on sleep behaviour in wild boar

description: R script containing code to run the models described in the manuscript
DOI: 10.6084/m9.figshare.28107950.v1
title: Supplementary File 1.pdf

description: This study presents the whole-genome sequence of <i>B. velezensis</i> B26- Supplementary file 1 provides MultiQC report.
DOI: 10.6084/m9.figshare.6269054.v1
title: Supplementary Material for: Beyond Irritable Bowel Syndrome: The Efficacy of the Low Fodmap Diet for Improving Symptoms in Inflammatory Bowel Diseases and Celiac Disease

description: <b><i>Background and Aim:</i></b> To evaluate the usefulness of a low FODMAP (Fermentable Oligosaccharides, Disaccharides, Monosaccharides, and Polyols) diet on patients with irritable bowel syndrome (IBS), non-active inflammatory bowel diseases (IBD), and celiac disease (CD) on a gluten-free diet (GFD). <b><i>Methods:</i></b> Dietetic interventional prospective study. IBS, IBD, and CD subjects were evaluated to check if they fulfilled the Rome III criteria. Each subject was educated to follow a low FODMAP diet after being evaluated by filling out questionnaires that assessed the quality of life (QoL) and symptoms experienced (IBS-SSS and SF-36), and was reevaluated after 1 and 3 months. <b><i>Results:</i></b> One hundred twenty-seven subjects were enrolled: 56 with IBS, 30 with IBD, and 41 with CD. IBS-SSS showed that abdominal symptoms improved after 1 and 3 months of diet in all subjects, with significant difference among the 3 groups at T0 (average scores IBS: 293 ± 137, IBD: 206 ± 86, CD: 222 ± 65, <i>p</i> &lt; 0.001), but no difference at T3 (IBS: 88 ± 54, IBD: 73 ± 45, CD: 77 ± 49, <i>p</i> = ns). By analyzing the SF-36 questionnaire, we did not observe any difference between the 3 groups, in terms of response to diet (<i>p</i> = ns), we observed a clinical improvement from T0 to T3 for most of the questionnaire’s domains. <b><i>Conclusions:</i></b> A low FODMAP diet could be a valid option to counter ­abdominal symptoms in patients with IBS, non-active IBD, or CD on a GFD, and thus, improve their QoL and social ­relations.
DOI: 10.17632/2bmw498btp
title: Impulse buying during livestream

description: the antecedents and consequences of impulse buying during livestreaming
DOI: 10.6084/m9.figshare.12250076.v1
title: Figure 4 - Biofilm Viability (Confocal).xlsx

description: RAW Data from the paper "<b>Cell death and biomass reduction in biofilms of multidrug resistant extended spectrum β-lactamase-producing uropathogenic <i>Escherichia coli</i> isolates by 1,8-cineole</b>" from Plos One.
DOI: 10.6084/m9.figshare.20153159.v1
title: Figures

description: Parkinson’s disease (PD) is a prevalent neurodegenerative disorder with indistinct etiology and ill-defined pathophysiology. A growing body of reports currently suggests that gut inflammation contributes to the pathogenesis of PD, but the mechanism remains largely unknown. The causes of gut inflammation are miscellaneous. One of such elements is a peripheral infection that can alter gut microbiota composition. <em>Citrobacter rodentium</em> (C.R), a kind of gram-negative bacteria, is an appropriate model organism to study inflammatory bowel disease (IBD) consisting of Ulcerative colitis (UC) and Crohn’s disease (CD). Hence, we hypothesize that C.R infection leading to pro-inflammatory circumstances initiate PD-like injuries or exacerbate the PD pathology in a MPTP-established PD mouse model. <strong>Results:</strong> Primarily, C.R delivery in mice induced an IBD-like symptom, including significant weight loss, increased mortality and water content in feces, gut barrier impairment, intestinal hyperpermeability and inflammation, microbial dysbiosis. Interestingly, C.R challenge altered DA (dopamine) metabolism in the brain via up-regulation the expression of MAOA (monoamine oxidase A) and MAOB (monoamine oxidase B). Secondly, compared to mice with the sole C.R infection or MPTP injection, the combination of C.R and MPTP caused the worse behavioral performances, the over-activation of microglia and astrocyte, the up-regulation of pro-inflammatory cytokines, the breakdown of the blood-brain barrier (BBB), and the dopaminergic degeneration in mice. Mechanistically, the C.R challenge increased the levels of TLR4 in the colon and the striatum. Simultaneously, RNAseq analysis showed the DEGs in the striatum mainly enriches in the PI3K-AKT signaling pathway, which implied the potential involvement of TLR4-PI3K-AKT signaling pathway in the disease condition.
DOI: 10.6084/m9.figshare.27852291.v1
title: <b>Concerns about Misinformation on Instagram in Five Countries</b>

description: Data and replication files to understand concerns about misinformation on Instagram using five country (Canada, France, the United Kingdom, the United States, and Germany) collected in January and February 2023.
DOI: 10.17632/jc39rkk4g8
title: Skin Cancer Screening Supplemental Material

description: A Cross-Sectional Study on Skin Cancer Screening Behaviors in Sexual Minorities Among Adults in the United States - Supplemental Materials
DOI: 10.17632/z7phmfz8yk
title: Structural and electronic properties of the perovskite-type ferrimagnetic semiconductor CaCo0.5Zr0.5O3

description: The purpose of this work is to report the structural, magnetic, electrical and electronic properties of the perovskite-type semiconductor CaCo0.5Zr0.5O3. For the synthesis of the material, the standard solid-state reaction method was employed, followed by an analysis of its crystal structure by Rietveld refinement applied to X-ray diffraction patterns, which revealed the crystallisation of the compound in an orthorhombic structure belonging to the Pcmn space group. Through morphological and compositional analyses, it was determined that the surface of the samples evidenced mean grain size of 1.47 ± 0.01 µm, as well as the occurrence of minimal levels of impurities. The curves of magnetic susceptibility as a function of temperature and magnetisation as a function of external magnetic field showed a weakly ferrimagnetic response of the material, with Weiss temperature =-72 K and effective magnetic moment 1.78 B, suggesting that Co4+ does not present crystalline field splitting and the spins adopt low spin states. The electrical resistivity exhibits behaviour and order of magnitude (106 .m) characteristic of a semiconductor feature and current-voltage curves with a typical thermistor-type semiconductor response. Density of states and band structure analysis indicate that the material exhibits ferromagnetic semiconductor-like behaviour at low temperatures, with a mean band gap of 0.89 eV and an effective magnetic moment of 2.0 µB.
DOI: 10.4121/uuid:76c46b83-c930-4798-a1c9-4be94dfeb741
title: Hospital Billing - Event Log

description: The 'Hospital Billing' event log was obtained from the financial modules of the ERP system of a regional hospital. The event log contains events that are related to the billing of medical services that have been provided by the hospital. Each trace of the event log records the activities executed to bill a package of medical services that were bundled together. The event log does not contain information about the actual medical services provided by the hospital. The 100,000 traces in the event log are a random sample of process instances that were recorded over three years. Several attributes such as the 'state' of the process, the 'caseType', the underlying 'diagnosis' etc. are included in the event log. Events and attribute values have been anonymized. The time stamps of events have been randomized for this purpose, but the time between events within a trace has not been altered. More information about the event log can be found in the related publications.
DOI: 10.6084/m9.figshare.1004939.v1
title: UK Higher Education Project Management Survey Data

description: This data set was derived from the UK Higher Education Project Management survey conducted in 2014 representing the sector's maturity during the academic year 2012-2013.
DOI: 10.6084/m9.figshare.25342486.v1
title: Single variant analysis for common variants

description: Summary data for "Single variant analysis for common variants".Note: Summary data for "GAD_7" and "Mental_distress" failed to upload in the first time and were uploaded later separately.
DOI: 10.6084/m9.figshare.3565074.v1
title: Full Archive

description: Full Archive
DOI: 10.17632/xh6sg437my
title: Nutrient Water Supply for Strawberry Plants in Greenhouse

description: Parameters/Features Abbreviation Measurement Date Date - Water Consumed Water Milli Liters Greenhouse Maximum Temperature GHMaxTemp °C Greenhouse Minimum Temperature GHMinTemp °C Greenhouse Average Temperature GHAveTemp °C Greenhouse Temperature Gap GHTempGap °C Greenhouse Maximum Humidity GHMaxHum % Greenhouse Minimum Humidity GHMinHum % Greenhouse Average Humidity GHAveHum % Greenhouse humidity gap GHHumGap % Greenhouse Maximum CO2 Value GHMaxCO2 ppm Greenhouse Minimum CO2 Value GHMinCO2 ppm Greenhouse Average CO2 Value GHAveCO2 ppm Greenhouse CO2 Value Gap GHCO2Gap ppm
DOI: 10.6084/m9.figshare.16674256.v1
title: P09

description: CCEP files for patient 9
DOI: 10.6084/m9.figshare.26153533.v1
title: Data for “Species differences in learning about gustatory and visual stimuli in two recently diverged species of Drosophila”, Animal Behaviour.

description: Learning is central to our understanding of how behaviour is shaped by the environment. A key open question is whether learning across contexts evolves as an integrated process, or whether learning in each context is free to evolve separately. Here, we measured learning in two sensory contexts in multiple genotypes and both sexes of two closely related, but ecologically divergent, species of fruit flies, <i>Drosophila simulans</i> and <i>Drosophila sechellia</i>. These species are morphologically very similar but differ dramatically in ecology and population biology. We tested how flies from each genotype, sex and species responded to and learned about different gustatory and visual cues. This approach allowed us to test whether species differences in learning were independent or correlated across contexts. Surprisingly, we found no evidence that <i>D. simulans</i> learned in any of our treatments. In contrast, <i>D. sechellia</i> learned to avoid gustatory stimuli that were paired with an aversive stimulus, as predicted, but unexpectedly learned to approach visual stimuli that were paired with the aversive stimulus. At the genotype level, genotypes, but not species, differed in their naïve responses to stimuli, but genotypes did not differ in learning in either species. Our results demonstrate that <i>D. sechellia</i> indeed differs from <i>D. simulans</i> in both learning contexts, but in a stimulus-dependent way. We suggest that studies of additional species or population pairs that employ this framework will be critical for evaluating the dimensionality of learning and its evolution.
DOI: 10.17632/77vtmjrhsm
title: A new finding relating subatomic particles' mass to the square of the magnetic flux quantum provides a novel interpretation of the mass and a novel Wave Function interpretation.

description: The motivation for investigating the issues presented in this article stemmed from a need to understand better the relationship in long-established physics formulas and extract the information they provided using conventional methods. Based on the definition of magnetic flux quantization, which is based on a combination of fundamental physical constants, the Planck constant, and the particle’s elementary charge, this work explores the results that arise when this equation is combined with the equation of the Bohr-level electrostatic force acting on the electron, which leads to a new mathematical relationship between the combined expressions. The new relationship yields novel theoretical findings related to the known universal constants. Following this insight, the formalism developed in this paper indicates that the mass of the electron and other subatomic particles is associated with the magnitude of the square of the magnetic flux quantum, which makes up the particle. This conclusion is not as strange as it may seem, as the square of the magnetic flux quantum appears in the context of magnetic energy in a current loop and, according to Einstein’s special theory of relativity, energy is equivalent to mass. Another aspect described at the end of this paper demonstrates the connection between the square of the magnetic flux quantum through the Bohr radius and the significance of the wave function in the atom. The theoretical results are in full accordance with experimental results published by NIST CODATA 2018 that I’ve used, which validates the existence of the relationship.