DOI: 10.3886/icpsr33444.v1
title: Center for Education and Drug Abuse Research (CEDAR): Etiological and Prospective Family Study in Southwestern Pennsylvania, Baseline Data, 1990-2011
title: Version 1

description: The Center for Education and Drug Abuse Research (CEDAR) conducts research on 775 families enrolled in the Center's prospective investigations into the etiology of substance use disorder (SUD). The pro-bands are men with lifetime presence/absence of SUD consequent to use of an illicit drug who have a 10-12 year old biological son or daughter. The biological children of SUD men are assigned to the high average risk (HAR) group whereas offspring of men without SUD, having neither axis 1 disorder ("normal") nor SUD psychiatric disorder, are assigned to the low average risk (LAR) group. A second control group (Psych control) was also collected, in whom the fathers had a lifetime DSM-III-R diagnosis of any psychiatric disorder not related to substance use. The sample sizes are as follows: HAR = 344, LAR = 350, and Psych = 81. The children are currently in varying stages of follow-up evaluation conducted at ages 12-14, 16, 19, and annually thereafter until age 30. CEDAR has already shown that they can predict in 10-12 year old youth cannabis use disorder by age 22 with approximately 70 percent accuracy, thereby substantiating the paradigm, subject recruitment strategy, and measurement protocols. Multidisciplinary research is conducted on family members (father, mother, children) with the objective of elucidating the genetic, bio-behavioral, and environmental factors on development of SUD consequent to use of illegal drugs. Research protocols are organized into three thematically connected research modules (Neurogenetics, Developmental Psychopathology, and Translation) linking etiology and prevention. The research components thus align with the NIH Roadmap model such that basic science informs clinical research leading to prevention guided by an understanding of etiology. In addition to module-level research, faculty also participate in three organizational aims: (1) Devise a practical scale to quantify the transmissible liability to SUD; (2) Empirically test a bio-psychological theory of SUD etiology focusing on off-time maturation leading to psychological dysregulation predisposing to SUD; and, (3) Delineate SUD liability variants within an ontogenetic framework.
description: Three groups of male and female children are studied for a 20-year period: (1) Offspring of substance abusing fathers, (2) Offspring of normal fathers, and (3) Offspring of psychiatrically disturbed fathers. The three groups are longitudinally tracked from age 10-12 until they reach age 30 using the following assessment schedule: age 10-12, age 12-14, age 16, age 19-30 (with annual evaluations).
description: ICPSR data undergo a confidentiality review and are altered when necessary to limit the risk of disclosure. ICPSR also routinely creates ready-to-go data files along with setups in the major statistical software formats as well as standard codebooks to accompany the data. In addition to these procedures, ICPSR performed the following processing steps for this data collection: Created variable labels and/or value labels.; Standardized missing values.; Checked for undocumented or out-of-range codes..
description: Presence of Common Scales: This study utilized the following measurement tools: Child Behavior Checklist (CBCL), Dimensions of Temperament - Revised (DOTs-R), Family Assessment Measure (FAM), Health Problems Checklist (HPQ), and Multidimensional Personality Questionnaire (MPQ).
description: Datasets: 
 
 DS0: Study-Level Files 
 DS1: Carbon Monoxide (CO) Monitoring 
 DS2: Child Behavior Checklist 
 DS3: Cognitive Errors Questionnaire 
 DS4: Demographic Form - Father 
 DS5: Demographic Form - Mother 
 DS6: Demographic Form - Index Case 
 DS7: Dimensions of Temperament Survey - Revised - Index Case 
 DS8: Dimensions of Temperament Survey - Revised - Father 
 DS9: Dimensions of Temperament Survey - Revised - Mother 
 DS10: Dimensions of Temperament Survey - Revised - Caregiver on Index Case 
 DS11: Drug Use Chart - Father 
 DS12: Drug Use Chart - Mother 
 DS13: Drug Use Chart - Caregiver on Index Case 
 DS14: Drug Use Chart - Index Case 
 DS15: Family Assessment Measure - General Scale - Father 
 DS16: Family Assessment Measure - General Scale - Mother 
 DS17: Family Assessment Measure - General Scale - Index Case 
 DS18: Family Assessment Measure - Dyadic Relationship Scale - Father on Index Case 
 DS19: Family Assessment Measure - Dyadic Relationship Scale - Index Case on Father 
 DS20: Family Assessment Measure - Dyadic Relationship Scale - Mother on Index Case 
 DS21: Family Assessment Measure - Dyadic Relationship Scale - Index Case on Mother 
 DS22: Family Assessment Measure - Dyadic Relationship Scale - Index Case on Sibling 
 DS23: Family Assessment Measure - Dyadic Relationship Scale - Sibling on Index Case 
 DS24: Family Assessment Measure - Self Rating Scale - Father 
 DS25: Family Assessment Measure - Self Rating Scale - Mother 
 DS26: Family Assessment Measure - Self Rating Scale - Index Case 
 DS27: Health Problems Checklist - Father 
 DS28: Health Problems Checklist - Mother 
 DS29: Multidimensional Personality Questionnaire - Father 
 DS30: Multidimensional Personality Questionnaire - Mother 
 DS31: Nursing Assessment 
 DS32: Psychiatric History Marker for DSM-III-R - Father 
 DS33: Psychiatric History Marker for DSM-III-R - Mother 
 DS34: Psychiatric History Marker for DSM-III-R - Index Case 
 DS35: Psychiatric History Marker for DSM-IV - Father 
 DS36: Psychiatric History Marker for DSM-IV - Mother 
 DS37: Psychiatric History Marker for DSM-IV - Index Case 
 DS38: Psychiatric Treatment History Questionnaire - Father 
 DS39: Psychiatric Treatment History Questionnaire - Mother 
 DS40: Psychiatric Treatment History Questionnaire - Index Case 
 DS41: Revised Parent-Adolescent Communication Form 
 DS42: Substance Use Questionnaire - Scale 
 DS43: Substance Use Questionnaire - Drug 
 DS44: Substance Use Questionnaire - Rank 
 DS45: Substance Use Questionnaire - Stop 
 DS46: Vigilance Task
description: cognitive assessment test, face-to-face interview, mail questionnaire, paper and pencil interview (PAPI), on-site questionnaire, telephone interview 
 For more information regarding the CEDAR study measures, users are encouraged to see the Center for Education and Drug Abuse Research (CEDAR) Web site.
description: Fathers, mothers, and biological children ages 10-12 in 1990 in Southeastern Pennsylvania whose father had a lifetime presence/absence of substance abuse disorder consequent to use of an illicit drug. Smallest Geographic Unit: Census tract
description: The sample uses a high risk paradigm, in which the families were selected based on a DSM-III-R diagnosis of substance use disorder in the biological father of the index child (High Average Risk, or HAR group) versus NO DSM-III-R psychiatric disorder (Low Average Risk, or LAR group). A second control group (Psych control) was also collected, in whom the fathers had a lifetime DSM-III-R diagnosis of any psychiatric disorder not related to substance use. The sample sizes are as follows: HAR = 344, LAR = 350, and Psych = 81. Citation: Tarter, R.E., Vanyukov, M.M. (2001). Introduction: Theoretical and operational framework for research into the etiology of substance use disorders. Journal of Child and Adolescent Substance Abuse 10 (4):1-12.