cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.3905252
title: Gene expression is encoded in all parts of a co-evolving interacting gene regulatory structure

description: <strong>Understanding the genetic regulatory code that governs gene expression is a primary challenge in molecular biology that opens up possibilities to cure human diseases and solve biotechnology problems. However, the fundamental question of how each of the individual coding and non-coding regions of the gene regulatory structure interact and contribute to the mRNA expression levels remains unanswered. Considering that all the information for gene expression regulation is already present in living cells, here we applied deep learning on over 20,000 mRNA datasets to discover the genetic regulatory code controlling mRNA expression in 7 model organisms ranging from bacteria to Human. We show that in all organisms, mRNA abundance can be predicted directly from the DNA sequence with high accuracy, demonstrating that up to 82% of the variation of gene expression levels is encoded in the gene regulatory structure. Coding and non-coding regions carry both overlapping and orthogonal information and jointly contribute to gene expression levels. By searching for DNA regulatory motifs present across the whole gene regulatory structure, we discover that motif interactions can regulate gene expression levels in a range of over three orders of magnitude. The uncovered co-evolution of coding and non-coding regions challenges the current paradigm that single motifs or regions are solely responsible for gene expression levels. Instead, we demonstrate how the holistic system that spans the entire gene regulatory structure, and which contains the right combination of all regulatory elements, is required to understand, control, and design any future gene expression systems.</strong>
DOI: 10.5281/zenodo.3905251
title: Gene expression is encoded in all parts of a co-evolving interacting gene regulatory structure

description: <strong>Understanding the genetic regulatory code that governs gene expression is a primary challenge in molecular biology that opens up possibilities to cure human diseases and solve biotechnology problems. However, the fundamental question of how each of the individual coding and non-coding regions of the gene regulatory structure interact and contribute to the mRNA expression levels remains unanswered. Considering that all the information for gene expression regulation is already present in living cells, here we applied deep learning on over 20,000 mRNA datasets to discover the genetic regulatory code controlling mRNA expression in 7 model organisms ranging from bacteria to Human. We show that in all organisms, mRNA abundance can be predicted directly from the DNA sequence with high accuracy, demonstrating that up to 82% of the variation of gene expression levels is encoded in the gene regulatory structure. Coding and non-coding regions carry both overlapping and orthogonal information and jointly contribute to gene expression levels. By searching for DNA regulatory motifs present across the whole gene regulatory structure, we discover that motif interactions can regulate gene expression levels in a range of over three orders of magnitude. The uncovered co-evolution of coding and non-coding regions challenges the current paradigm that single motifs or regions are solely responsible for gene expression levels. Instead, we demonstrate how the holistic system that spans the entire gene regulatory structure, and which contains the right combination of all regulatory elements, is required to understand, control, and design any future gene expression systems.</strong>
DOI: 10.5281/zenodo.3776748
title: Mesquita et al 2020

description: Data used in the paper "In-situ observations of neutral shear instability in the statically stable high-latitude mesosphere and lower thermosphere during quiet magnetic conditions". Data includes "pyglow-master.zip", which is the python code used to generate the empirical model results.
DOI: 10.5281/zenodo.3905269
title: edexter/MAR: Initial release of project

description: Data and code pertaining "Modeling the trophic impacts of invasive zooplankton in a highly invaded river"
DOI: 10.5281/zenodo.3905268
title: edexter/MAR: Initial release of project

description: Data and code pertaining "Modeling the trophic impacts of invasive zooplankton in a highly invaded river"
DOI: 10.5281/zenodo.3905255
title: Scholarly journals publishing articles by family and community physicians in Brazil, up to December 2018

description: This is the dataset of manuscript titled "In which journals do family and community physicians in Brazil publish? The <em>Trajetórias MFC</em> project". There are two spreadsheets: the dataset proper and the data dictionary. See the manuscript for background. All spreadsheets are in the CSV (comma-separated values) format, delimited with semicolons and encoded in UTF-8 with the byte-order mark (BOM). The spreadsheets can be opened with desktop or Web application software (LibreOffice Calc, Microsoft Excel, Google Sheets) or with statistical software such as R. See also the preprint, dataset and supplementary table for an earlier milestone, about the postgraduate education of family and community physicians in Brazil.
DOI: 10.7910/dvn/dul9kt/vg2jrl
title: Final pooled DCE data _difference in variables.tab

description: FNP DCE data
DOI: 10.21227/hh9b-yp17
title: MQTT Internet of Things Intrusion Detection Dataset

description: Message Queuing Telemetry Transport (MQTT) protocol is one of the most recent standards used in Internet of Things (IoT) machine to machine communication. The increase in the number of available IoT devices and used protocols reinforce the need for new and robust Intrusion Detection Systems (IDS). However, building IoT IDS requires the availability of datasets to process, train and evaluate these models. The dataset presented in this paper is the first to simulate and MQTT-based network. The dataset is generated using a simulated MQTT network architecture. The network comprises twelve sensors, a broker, a simulated camera, and an attacker. Five scenarios are recorded: (1) normal operation, (2) aggressive scan, (3) UDP scan, (4) Sparta SSH brute-force, and (5) MQTT brute-force attack. The raw pcap files are saved, then features are extracted. Three abstraction levels of features are extracted from the raw pcap files: (a) packet features, (b) Unidirectional flow features and (c) Bidirectional flow features. The csv feature files in the dataset are suited for Machine Learning (ML) usage. Also, the raw pcap files are suitable for the deeper analysis of MQTT IoT networks communication and the associated attacks.
DOI: 10.21227/45ry-q565
title: MQTT Internet of Things Intrusion Detection Dataset

description: Message Queuing Telemetry Transport (MQTT) protocol is one of the most recent standards used in Internet of Things (IoT) machine to machine communication. The increase in the number of available IoT devices and used protocols reinforce the need for new and robust Intrusion Detection Systems (IDS). However, building IoT IDS requires the availability of datasets to process, train and evaluate these models. The dataset presented in this paper is the first to simulate and MQTT-based network. The dataset is generated using a simulated MQTT network architecture. The network comprises twelve sensors, a broker, a simulated camera, and an attacker. Five scenarios are recorded: (1) normal operation, (2) aggressive scan, (3) UDP scan, (4) Sparta SSH brute-force, and (5) MQTT brute-force attack. The raw pcap files are saved, then features are extracted. Three abstraction levels of features are extracted from the raw pcap files: (a) packet features, (b) Unidirectional flow features and (c) Bidirectional flow features. The csv feature files in the dataset are suited for Machine Learning (ML) usage. Also, the raw pcap files are suitable for the deeper analysis of MQTT IoT networks communication and the associated attacks.
DOI: 10.5281/zenodo.3905311
title: TCTracer Evaluation Data - International Conference on Software Engineering 2020

description: This repository provides the data artefacts for the experiments conducted using our tool TCtracer for the International Conference on Software Engineering (ICSE) 2020 paper "Establishing Multilevel Test-to-Code Traceability Links".
DOI: 10.14272/peqhirfakiasbk-uhfffaoysa-n/chmo0000593
title: 1H nuclear magnetic resonance spectroscopy (1H NMR) (tritylbenzene)
title: InChI=1S/C25H20/c1-5-13-21(14-6-1)25(22-15-7-2-8-16-22,23-17-9-3-10-18-23)24-19-11-4-12-20-24/h1-20H

description: dataset for 1H nuclear magnetic resonance spectroscopy (1H NMR) 1H NMR (300 MHz, DMSO-d6 [2.50 ppm], ppm) δ = 7.33–7.28 (m, 8H, Car.H), 7.23–7.20 (m, 4H, Car.H), 7.18–7.13 (m, 8H, CarH).
DOI: 10.14272/peqhirfakiasbk-uhfffaoysa-n/chmo0000630
title: infrared absorption spectroscopy (IR) (tritylbenzene)
title: InChI=1S/C25H20/c1-5-13-21(14-6-1)25(22-15-7-2-8-16-22,23-17-9-3-10-18-23)24-19-11-4-12-20-24/h1-20H

description: dataset for infrared absorption spectroscopy (IR) IR (ATR, ṽ) = 3084 (vw), 3055 (w), 3029 (w), 3017 (w), 1672 (w), 1592 (w), 1490 (m), 1441 (w), 1385 (w), 1183 (w), 1081 (w), 1034 (w), 1002 (w), 765 (m), 749 (vs), 700 (vs), 633 (s), 620 (w), 588 (w), 564 (vw), 548 (vw), 524 (w), 511 (vw), 492 (w) cm–1.
DOI: 10.14272/peqhirfakiasbk-uhfffaoysa-n/chmo0000470
title: mass spectrometry (MS) (tritylbenzene)
title: InChI=1S/C25H20/c1-5-13-21(14-6-1)25(22-15-7-2-8-16-22,23-17-9-3-10-18-23)24-19-11-4-12-20-24/h1-20H

description: dataset for mass spectrometry (MS) EI (m/z, 70 eV, 110 °C): 320 (56) [M+], 243 (100) [M+ – C6H5], 165 (60) [M+ – 2 C6H5 –H].HRMS–EI (m/z): [M]+ calcd for C25H20, 320.1565; found, 320.1566.
DOI: 10.14272/peqhirfakiasbk-uhfffaoysa-n.1
title: tritylbenzene
title: InChI=1S/C25H20/c1-5-13-21(14-6-1)25(22-15-7-2-8-16-22,23-17-9-3-10-18-23)24-19-11-4-12-20-24/h1-20H

description: This dataset contains experimental data from a sample (tritylbenzene, InChI=1S/C25H20/c1-5-13-21(14-6-1)25(22-15-7-2-8-16-22,23-17-9-3-10-18-23)24-19-11-4-12-20-24/h1-20H). The datasets from the following experiments are available: mass spectrometry (MS) infrared absorption spectroscopy (IR) 1H nuclear magnetic resonance spectroscopy (1H NMR)
DOI: 10.5281/zenodo.3905319
title: PHASTA compressible test case for two processes

description: Input files and execution instructions for PHASTA on a Stampede2 Skylake node using two processes. The expected results are included in the included README.md.
DOI: 10.14272/birldgkmjjezri-uhfffaoysa-n.1
title: 1-bromo-4-[1,2,2-tris(4-bromophenyl)ethenyl]benzene
title: InChI=1S/C26H16Br4/c27-21-9-1-17(2-10-21)25(18-3-11-22(28)12-4-18)26(19-5-13-23(29)14-6-19)20-7-15-24(30)16-8-20/h1-16H

description: This dataset contains experimental data from a sample (1-bromo-4-[1,2,2-tris(4-bromophenyl)ethenyl]benzene, InChI=1S/C26H16Br4/c27-21-9-1-17(2-10-21)25(18-3-11-22(28)12-4-18)26(19-5-13-23(29)14-6-19)20-7-15-24(30)16-8-20/h1-16H). The datasets from the following experiments are available: infrared absorption spectroscopy (IR) mass spectrometry (MS) 1H nuclear magnetic resonance spectroscopy (1H NMR) 13C nuclear magnetic resonance spectroscopy (13C NMR)
DOI: 10.14272/birldgkmjjezri-uhfffaoysa-n/chmo0000470
title: mass spectrometry (MS) (1-bromo-4-[1,2,2-tris(4-bromophenyl)ethenyl]benzene)
title: InChI=1S/C26H16Br4/c27-21-9-1-17(2-10-21)25(18-3-11-22(28)12-4-18)26(19-5-13-23(29)14-6-19)20-7-15-24(30)16-8-20/h1-16H

description: dataset for mass spectrometry (MS) EI (m/z, 70 eV, 140 °C): 652/650/648/646/644 (18/67/100/70/16) [M+], 571/569/567/565 (10/30/32/12) [M+ – Br], 490/488/486 (9/13/5) [M+ – 2 Br], 409/407 (6/7) [M+ – 3 Br], 328 (27) [M+ – 4 Br], 327 (32) [M+ – 4 Br – H], 326 (32) [M+ – 4 Br – 2 H], 252 (34) [C20H12+], 164 (44), 163 (34).HRMS–FAB (m/z): [M+] calcd for C26H1679Br281Br2, 647.7945; found, 647.7944.HRMS–FAB (m/z): [M+] calcd for C26H1679Br4, 643.7985; found, 643.7986.
DOI: 10.14272/birldgkmjjezri-uhfffaoysa-n/chmo0000595
title: 13C nuclear magnetic resonance spectroscopy (13C NMR) (1-bromo-4-[1,2,2-tris(4-bromophenyl)ethenyl]benzene)
title: InChI=1S/C26H16Br4/c27-21-9-1-17(2-10-21)25(18-3-11-22(28)12-4-18)26(19-5-13-23(29)14-6-19)20-7-15-24(30)16-8-20/h1-16H

description: dataset for 13C nuclear magnetic resonance spectroscopy (13C NMR) 13C NMR (100 MHz, Dichloromethane-d2 [54.0 ppm], ppm) δ = 142.2 (2C, Cq), 140.3 (4C, Cq), 133.4 (8C, CarH), 131.8 (8C, CarH), 121.6 (4C, CqBr).
DOI: 10.14272/birldgkmjjezri-uhfffaoysa-n/chmo0000593
title: 1H nuclear magnetic resonance spectroscopy (1H NMR) (1-bromo-4-[1,2,2-tris(4-bromophenyl)ethenyl]benzene)
title: InChI=1S/C26H16Br4/c27-21-9-1-17(2-10-21)25(18-3-11-22(28)12-4-18)26(19-5-13-23(29)14-6-19)20-7-15-24(30)16-8-20/h1-16H

description: dataset for 1H nuclear magnetic resonance spectroscopy (1H NMR) 1H NMR (400 MHz, Dichloromethane-d2 [5.32 ppm], ppm) δ = 7.30–7.34 (m, 8H, CarH), 6.90–6.93 (m, 8H, CarH).
DOI: 10.14272/birldgkmjjezri-uhfffaoysa-n/chmo0000630
title: infrared absorption spectroscopy (IR) (1-bromo-4-[1,2,2-tris(4-bromophenyl)ethenyl]benzene)
title: InChI=1S/C26H16Br4/c27-21-9-1-17(2-10-21)25(18-3-11-22(28)12-4-18)26(19-5-13-23(29)14-6-19)20-7-15-24(30)16-8-20/h1-16H

description: dataset for infrared absorption spectroscopy (IR) IR (ATR, ṽ) = 1581 (w), 1483 (vs), 1392 (m), 1103 (w), 1069 (s), 1007 (vs), 975 (w), 963 (w), 863 (m), 817 (vs), 792 (vs), 765 (w), 735 (m), 717 (w), 700 (w), 652 (w), 632 (w), 623 (w), 567 (w), 503 (s), 489 (s), 477 (s), 391 (w) cm–1.
DOI: 10.7910/dvn/pg7bho/6hnhwd
title: supplementary_data.tgz

description: :unav
DOI: 10.7910/dvn/pg7bho/tnobvu
title: supplementary_data.tgz

description: :unav
DOI: 10.7910/dvn/pg7bho/ydsdki
title: supplementary_data.tgz

description: README for each file now includes stacking information for validation.
DOI: 10.5281/zenodo.3905327
title: Bartonella spp. infection in nest fleas and arctic foxes from Karrak Lake, NU

description: PCR results for fleas and foxes tested for Bartonella spp. DNA via conventional and qPCR.
DOI: 10.5281/zenodo.3834904
title: Bartonella spp. infection in nest fleas and arctic foxes from Karrak Lake, NU

description: PCR results for fleas and foxes tested for Bartonella spp. DNA via conventional and qPCR.
DOI: 10.5281/zenodo.3905313
title: Data for Breivik et al. 2020 COSMIC Release

description: Contains all necessary data to reproduce all plots of Breivik et al. 2020 using version 3.3 of COSMIC (Compact Object Synthesis and Monte Carlo Investigation Code)
DOI: 10.5281/zenodo.3905312
title: Data for Breivik et al. 2020 COSMIC Release

description: Contains all necessary data to reproduce all plots of Breivik et al. 2020 using version 3.3 of COSMIC (Compact Object Synthesis and Monte Carlo Investigation Code)
DOI: 10.25919/5ef277c5cd060
title: Parkes observations for project P1043 semester 2020APRS_01

description: We propose observations with the ultra-wide-bandwidth, low frequency receiver (UWL) installed at the Parkes telescope to carry out single pulse study of millisecond pulsars. We have selected two of the brightest pulsars that are regularly observed by the Parkes Pulsar Timing Array. Our observations will enable statistical properties study of single pulses with ultra-wide-bandwidth, measuring jitter noise level of the linear and circular polarization states as well as in the total intensity signal, measuring jitter bandwidth and how jitter noise decorrelates with frequency. The UWL receiver, with its much wider bandwidth, will provide unique opportunity for study of jitter noise evolution with frequency.
DOI: 10.14457/mu.the.2000.829
title: In vitro studies on seed germination and plant growth of Vanda and Phaius
DOI: 10.14457/mu.the.2000.830
title: Study on the effect of 2, 6-dihydroxyacetophenone on cholesterol metabolism in hyperlipidemic hamsters
DOI: 10.14457/mu.the.2000.831
title: Polymorphisms and mutations of apolipoprotein B and apolipoprotein E genes in Thai subjects
DOI: 10.14457/mu.the.2000.832
title: Study of protease inhibitor in rubber latex
DOI: 10.14457/mu.the.2000.833
title: Microvascularization of the midbrain in common tree shrew (Tupaia glis)
DOI: 10.14457/mu.the.2000.834
title: Insulin-like growth factor-I promotes maturation rate of the domestic cat oocytes in vitro
DOI: 10.14457/mu.the.2000.835
title: Tidal wave height analysis at the coast Paknam Tachin, Ko Sichang and Hua-Hin
DOI: 10.14457/mu.the.2000.836
title: The effects of relaxation training on pre and postoperative anxiety of patients undergoing a total abdominal hysterectomy
DOI: 10.14457/mu.the.2000.837
title: Effects of cardiac rehabilitation on the exercise capacity and quality of life in patients with myocardial infarction
DOI: 10.14457/mu.the.2000.838
title: Cost-effectiveness of directly observed treatment, short course versus self-aministered treatment of pulmonary tuberculosis
DOI: 10.14457/mu.the.2000.839
title: Factors of mothers' health behavior related to severity of acute respiratory infection in children under 5 years
DOI: 10.14457/mu.the.2000.840
title: Physician shortages in community hospital
DOI: 10.14457/mu.the.2000.841
title: Risk factors of urinary tract infection in the elderly patients in Maharat Nakhonratchasima hospital
DOI: 10.14457/mu.the.2000.842
title: Efficiency of an anaerobic sequencing batch reactor (AnA2/O2 SBR) in the treatment of textile wastewater /
DOI: 10.14457/mu.the.2000.843
title: A study of low density polyethylene and polystyrene blends with reactive compatibilisers
DOI: 10.14457/mu.the.1999.937
title: Detection of Chlamydia pneumoniae in chronic obstructive pulmonary disease with acute respiratory illness
DOI: 10.14457/mu.the.1999.938
title: A study on the short tandem repeat system (STRs) locus DYS385 in Thai population
DOI: 10.14457/mu.the.2000.844
title: Laboratory investigation of viral eitologic agents in pediatric patients with acute viral encephalitis
DOI: 10.14457/mu.the.2000.845
title: Development of sub-district administration organization potentiality on AIDS prevention and control through empowerment process in Nonsawang sub-district, Kudkhaopun district, Ubon Ratchathani province
DOI: 10.14457/mu.the.2000.846
title: The effectiveness of the self-help group towards the child care behaviors of HIV-infected mothers with anxiety at Queen Sirikit National Institute of Child Health
DOI: 10.14457/mu.the.2000.847
title: Effects of a dental health education program on oral health care provided to preschool children by their mothers
DOI: 10.14457/mu.the.2000.848
title: Detection of delta-endotoxin genes from local isolates of Bacillus thuringiensis by polymerase chain reaction
DOI: 10.14457/mu.the.2000.849
title: The effectiveness of protection motivation theory and social support as applied to a health education program on dengue heamorrphagic fever prevention among grade 5 students
DOI: 10.14457/mu.the.2000.850
title: Roles and behaviros of foundation volunteers in assisting society as perceived by metropolitan investigation police
DOI: 10.14457/mu.the.2000.851
title: A phonological study of Pa-O (Taungthu) at Ban Huay Salop, Tambon Huay Pha, Munag District Mae Hong Son province
DOI: 10.14457/mu.the.2000.852
title: Factors affecting job satisfaction of correctional officers in the Bangkok region
DOI: 10.14457/mu.the.2000.853
title: Some factors affecting performane achievement of the investigators in Metropolitan Police Bureau
DOI: 10.14457/mu.the.2000.854
title: An analysis of the causality of violent offenses committed by the young male offenders
DOI: 10.14457/mu.the.2000.855
title: A physochemical study of anti-herper simplex components from Gynura procumbens Merr
DOI: 10.14457/mu.the.2000.856
title: The evaluation of environmental study course management of the nursing science programme Ministry of Public Health
DOI: 10.14457/mu.the.2000.857
title: Production of monoclonal antibodies against Penicillium marneffei antigens and molecular epidemiology of Penicillium marneffei infection in Thailand
DOI: 10.14457/mu.the.2000.858
title: Effect of exercise on fructose absorption facilitated by alanine and physical performance
DOI: 10.14457/mu.the.2000.859
title: A proposed model of provincial environmental education centers
DOI: 10.14457/mu.the.2000.860
title: Thailand health management scenarios in the next two decades (2020)
DOI: 10.14457/mu.the.2000.861
title: Factors associated with menopausal symptoms : a study at health clinic, health promotion center region 1
DOI: 10.14457/mu.the.2000.862
title: Microvascularization of pons in the common tree shrew (Tupaia glis)
DOI: 10.14457/mu.the.2000.863
title: The adjusted corrective constant factor for audiometric test
DOI: 10.14457/mu.the.2000.864
title: Study on the expression of hepatitis B surface and its modified genes in Saccharomyces cerevisiae
DOI: 10.14457/mu.the.2000.865
title: Lactose digestion and tolerance after yogurt tablet consumption in adolescents
DOI: 10.14457/mu.the.2000.866
title: Adsorption of copper(II) and zinc(II) in 0.01 M hydrochloric acid solution by chitosans
DOI: 10.14457/mu.the.2000.867
title: Effects of formative assessment on motivation and learning outcomes of first year students at Wang Klai Kangwon Campus, Rajamangala Institute of Technology
DOI: 10.14457/mu.the.2000.868
title: A phonological study of Yangon Burmes
DOI: 10.25387/g3.12458255
title: Supplemental Material for Humble et al., 2020

description: Humble et al Supplementary Material.pdf: PDF file containing Supplementary Tables and Figures to accompany the manuscript<br>Agaz_array_77661_genotypes.vcf: VCF file containing 77661 genotypes for 276 Antarctic fur seal samples<br>Agaz_array_85359_flanking_sequences.txt: Text file containing the flanking sequences for all 85,359 SNPs tiled on the Agaz 85K genotyping array.
DOI: 10.25387/g3.12458255.v2
title: Supplemental Material for Humble et al., 2020

description: Humble et al Supplementary Material.pdf: PDF file containing Supplementary Tables and Figures to accompany the manuscript<br>Agaz_array_77661_genotypes.vcf: VCF file containing 77661 genotypes for 276 Antarctic fur seal samples<br>Agaz_array_85359_flanking_sequences.txt: Text file containing the flanking sequences for all 85,359 SNPs tiled on the Agaz 85K genotyping array.
DOI: 10.25387/g3.12458255.v1
title: Supplemental Material for Humble et al., 2020

description: Humble et al Supplementary Material.pdf: PDF file containing Supplementary Tables and Figures to accompany the manuscript<br>Agaz_array_77661_genotypes.vcf: VCF file containing 77661 genotypes for 276 Antarctic fur seal samples<br>Agaz_array_85359_flanking_sequences.txt: Text file containing the flanking sequences for all 85,359 SNPs tiled on the Agaz 85K genotyping array.
DOI: 10.6084/m9.figshare.3761562.v1533
title: Online Labour Index: Measuring the Online Gig Economy for Policy and Research

description: Data repository for the data underlying the Online Labour Index. See http://ilabour.oii.ox.ac.uk online-labour-index/ for details.
DOI: 10.3886/e120001v1-25082
title: Resilience and Mental Health among Juveniles

description: The aim of the first study (Study 1) is to analyse the relationship between resilience and the broadly-understood mental health of juveniles admitted to youth education centres. Study 2 aimed to understand the direct and indirect role of resilience in shaping the mental health of juveniles. In the model we tested, we looked at the relationship among resilience, coping strategies, and mental well-being. The first study involved 201 juveniles, the second involved 253 juveniles. The results of both studies have shown that resilience is an important predictor of mental health of juveniles. The obtained results indicate that work on the level of juvenile resilience leads to strengthening of positive mental health indicators and buffering of negative indicators.