cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7102055
title: Refraction and eye anterior segment parameters in schizophrenic patients

description: ABSTRACT Purpose: To evaluate the difference in terms of refractive errors and anterior segment parameters between schizophrenic patients and healthy volunteers. Methods: This study compared 70 patients (48 men) who were diagnosed with schizophrenia with a control group of 60 (35 men) who were similar in terms of age, gender, education, and socioeconomic level. Anterior segment examination was performed using a Scheimflug system. Axial length and lens thickness (LT) were measured using optic biometry. The following tests were administered to the psychiatric patient group: Brief Psychiatric Rating Scale (BPRS), Scale for the Assessment of Negative Symptoms (SANS), and Scale for the Assessment of Positive Symptoms (SAPS). Results: Mild myopia was detected in both the schizophrenic and control groups, with no statistically significant difference (p&gt;0.005). Corneal volume (CV), anterior chamber volume (ACV), anterior chamber depth (ACD), and central corneal thickness (CCT) values were lower in the schizophrenic group, and there was a statistically significant between-group difference (p=0.026, p=0.014, p=0.048, and p=0.005, respectively). LT was greater in schizophrenics, and the difference was found to be statistically significant (p=0.006). A statistically significant negative correlation was found between SAPS and cylinder values (p=0.008). The axial eye length, cylinder value, pupil diameter, mean keratometric value, and anterior chamber angle revealed no statistically significant difference between the groups (p&gt;0.05). Conclusion: No statistically significant difference was detected in terms of refraction disorders between schizophrenics and the healthy control group, while some differences in anterior chamber parameters were present. These results demonstrate that schizophrenics may exhibit clinical and structural differences in the eye.
DOI: 10.6084/m9.figshare.7102058.v1
title: Bibliographical Survey on Special Education and Teaching Science in Brazil

description: ABSTRACT: With the World Declaration of Education for All, Brazil has opted to build an inclusive education system. Thus, it is necessary that Special Education is also the subject of research on Teaching Science, but studies indicate that there is little research in this area. As such, the aim of this work was to carry out a national bibliographical survey to evaluate how the research area of teaching Science has approached the Special Education theme. The bibliographic research was carried out in line with the revision procedures defined by Content Analysis and used six journals of strata A1 and A2 defined by CAPES qualis as corpus of information. The searches were carried out from five descriptors: inclusion, inclusive education, special education, special educational needs and teacher education. According to the selection criteria, only 28 papers were found: 15 on teaching Science and learning; 12 on the education of Science teachers from the perspective of Special Education and one on evaluation and curriculum for Special Education. Most of these works were written by Éder Pires de Camargo and Anna Maria Canavarro Benite, and the teaching of Physics for the visually impaired is the theme that has been published the most. The publications began in 2006, reaching the largest number of publications in 2015. The results show that the amount of research in this area is still incipient, having little representation compared to the total number of publications in the best evaluated journals.
DOI: 10.6084/m9.figshare.7102049
title: Visual loss resulting from immunosuppressive therapy in patients with syphilitic uveitis

description: ABSTRACT Permanent visual loss can be caused by improper use of immunosuppressive therapy in cases of uveitis without differential diagnosis of syphilitic uveitis. We present four cases of syphilitic uveitis that were incorrectly diagnosed as being secondary to rheumatic diseases and were subsequently treated with immunosuppressive therapy, leading to permanent visual loss. These cases highlight the importance of ruling out syphilis in the differential diagnosis of inflammatory ocular diseases before starting use of immunosuppressive therapy.
DOI: 10.6084/m9.figshare.7102049.v1
title: Visual loss resulting from immunosuppressive therapy in patients with syphilitic uveitis

description: ABSTRACT Permanent visual loss can be caused by improper use of immunosuppressive therapy in cases of uveitis without differential diagnosis of syphilitic uveitis. We present four cases of syphilitic uveitis that were incorrectly diagnosed as being secondary to rheumatic diseases and were subsequently treated with immunosuppressive therapy, leading to permanent visual loss. These cases highlight the importance of ruling out syphilis in the differential diagnosis of inflammatory ocular diseases before starting use of immunosuppressive therapy.
DOI: 10.6084/m9.figshare.7102043
title: Acute retinal necrosis following intravitreal dexamethasone (Ozurdex®) implant

description: A 52-year-old woman undergoing azathioprine treatment for rheumatoid arthritis developed acute retinal necrosis a month after intravitreal dexamethasone (Ozurdex ®) implantation for posterior uveitis in the left eye. Varicella zoster virus (VZV) DNA was detected in the anterior chamber and vitreous samples on polymerase chain reaction (PCR) analysis. Retinal detachment occurred despite systemic and intravitreal antiviral therapy. Favorable structural and functional outcomes were achieved after retinal surgery with silicone oil. To the authors’ knowledge, this is the first reported case of acute retinal necrosis following placement of an Ozurdex® implant. Physicians practicing Ozurdex® implantations should be aware of this unusual but devastating complication. Extra caution and frequent follow-up are required in all immunocompromised patients receiving Ozurdex® implantation.
DOI: 10.6084/m9.figshare.7102046
title: Diversity of parameters in the muscle strength evaluation of Brazilian school children and adolescents: a systematic review

description: Abstract Muscle strength (MS) is considered important indicative of global health regardless of age or clinical condition. The aim of this study was to summarize evidence from research carried out in Brazil that investigated MS in school children and adolescents, showing the objectives, tests, protocols and quantitative of youngsters who met the health criteria for MS. Systematic review conducted in the PubMed, Web of Science, Scopus, Sportdiscus, LILACS and Scielo databases, with complementary searches in reference lists. In all articles, the risk of bias was analyzed. Of the 15,609 articles initially identified, 27 were included, comprising data from 29,604 children and adolescents. The 27 studies included presented moderate (37%) and low risk of bias (63%). Three out of four studies investigating MS in children and adolescents were carried out in southern and southeastern Brazil (77.7%). It was found that 65.9% of boys and 58.2% of girls had adequate levels of MS for health, with results varying from 14.8% to 66.0% in girls and from 20.4% to 76.9% in boys. Several MS measurement protocols were identified; however, horizontal jump was the most used test to evaluate MS (59.2%). MS is a physical valence searched in children and adolescents and a variety of protocols are used. In addition, it is necessary to propose MS cutoff points based on health criteria for the accurate estimation of this physical valence in children and adolescents in Brazil.
DOI: 10.6084/m9.figshare.7102043.v1
title: Acute retinal necrosis following intravitreal dexamethasone (Ozurdex®) implant

description: A 52-year-old woman undergoing azathioprine treatment for rheumatoid arthritis developed acute retinal necrosis a month after intravitreal dexamethasone (Ozurdex ®) implantation for posterior uveitis in the left eye. Varicella zoster virus (VZV) DNA was detected in the anterior chamber and vitreous samples on polymerase chain reaction (PCR) analysis. Retinal detachment occurred despite systemic and intravitreal antiviral therapy. Favorable structural and functional outcomes were achieved after retinal surgery with silicone oil. To the authors’ knowledge, this is the first reported case of acute retinal necrosis following placement of an Ozurdex® implant. Physicians practicing Ozurdex® implantations should be aware of this unusual but devastating complication. Extra caution and frequent follow-up are required in all immunocompromised patients receiving Ozurdex® implantation.
DOI: 10.6084/m9.figshare.7102046.v1
title: Diversity of parameters in the muscle strength evaluation of Brazilian school children and adolescents: a systematic review

description: Abstract Muscle strength (MS) is considered important indicative of global health regardless of age or clinical condition. The aim of this study was to summarize evidence from research carried out in Brazil that investigated MS in school children and adolescents, showing the objectives, tests, protocols and quantitative of youngsters who met the health criteria for MS. Systematic review conducted in the PubMed, Web of Science, Scopus, Sportdiscus, LILACS and Scielo databases, with complementary searches in reference lists. In all articles, the risk of bias was analyzed. Of the 15,609 articles initially identified, 27 were included, comprising data from 29,604 children and adolescents. The 27 studies included presented moderate (37%) and low risk of bias (63%). Three out of four studies investigating MS in children and adolescents were carried out in southern and southeastern Brazil (77.7%). It was found that 65.9% of boys and 58.2% of girls had adequate levels of MS for health, with results varying from 14.8% to 66.0% in girls and from 20.4% to 76.9% in boys. Several MS measurement protocols were identified; however, horizontal jump was the most used test to evaluate MS (59.2%). MS is a physical valence searched in children and adolescents and a variety of protocols are used. In addition, it is necessary to propose MS cutoff points based on health criteria for the accurate estimation of this physical valence in children and adolescents in Brazil.
DOI: 10.6084/m9.figshare.7102037
title: Idiopathic polypoidal choroidal vasculopathy masquerading as choroidal tumors: one year follow-up of a peripheral lesion

description: ABSTRACT This case report describes peripheral idiopathic polypoidal choroidal vasculopathy (IPCV) with a collection of small aneurysmal dilations that masqueraded as choroidal tumors in an elderly patient. A 68-year-old African American woman was referred to us with a suspected diagnosis of asymptomatic vascular choroidal tumor and choroidal capillary hemangioma, affecting the temporal peripheral fundus. Upon examination, optical coherence tomography (OCT) revealed two large hemorrhagic pigment epithelium detachments (PED), and indocyanine green angiography (ICG) confirmed the diagnosis of IPCV. One year later, there was reduction in the hemorrhagic pigment epithelium detachments and the lesion took on a different appearance, resembling a choroidal osteoma. No treatment was necessary despite the presence of multiple polyps. IPCV is a rare condition that can resemble other choroidal diseases depending on the stage of presentation. OCT is the best tool to determine the characteristics of the lesions, and indocyanine green angiography should be used to confirm the diagnosis. Not all cases require treatment.
DOI: 10.6084/m9.figshare.7102037.v1
title: Idiopathic polypoidal choroidal vasculopathy masquerading as choroidal tumors: one year follow-up of a peripheral lesion

description: ABSTRACT This case report describes peripheral idiopathic polypoidal choroidal vasculopathy (IPCV) with a collection of small aneurysmal dilations that masqueraded as choroidal tumors in an elderly patient. A 68-year-old African American woman was referred to us with a suspected diagnosis of asymptomatic vascular choroidal tumor and choroidal capillary hemangioma, affecting the temporal peripheral fundus. Upon examination, optical coherence tomography (OCT) revealed two large hemorrhagic pigment epithelium detachments (PED), and indocyanine green angiography (ICG) confirmed the diagnosis of IPCV. One year later, there was reduction in the hemorrhagic pigment epithelium detachments and the lesion took on a different appearance, resembling a choroidal osteoma. No treatment was necessary despite the presence of multiple polyps. IPCV is a rare condition that can resemble other choroidal diseases depending on the stage of presentation. OCT is the best tool to determine the characteristics of the lesions, and indocyanine green angiography should be used to confirm the diagnosis. Not all cases require treatment.
DOI: 10.6084/m9.figshare.7102040
title: Association between visual impairment and depression in the elderly: a systematic review

description: ABSTRACT A systematic review was conducted to investigate the relationship between visual impairment and depression in the elderly. We searched electronic databases (LILACS, SciELO, MEDLINE, and Cochrane Central Register of Controlled Trials) from inception to August 2014 and researched the described references. The search strategy used the following terms: (visual impairment or blindness) and (elderly) and (depression). Of the 641 electronics, 42 works were selected in full and another 20 were identified as being possibly relevant. Ten studies were included. The studies ranged in sample size from 31 to 21,995 participants. Depression was associated with visual impairment in all studies; however, without standardization of diagnostic tests, we could not conduct a meta-analysis or establish a relationship between visual impairment and depression in the elderly.
DOI: 10.6084/m9.figshare.7102040.v1
title: Association between visual impairment and depression in the elderly: a systematic review

description: ABSTRACT A systematic review was conducted to investigate the relationship between visual impairment and depression in the elderly. We searched electronic databases (LILACS, SciELO, MEDLINE, and Cochrane Central Register of Controlled Trials) from inception to August 2014 and researched the described references. The search strategy used the following terms: (visual impairment or blindness) and (elderly) and (depression). Of the 641 electronics, 42 works were selected in full and another 20 were identified as being possibly relevant. Ten studies were included. The studies ranged in sample size from 31 to 21,995 participants. Depression was associated with visual impairment in all studies; however, without standardization of diagnostic tests, we could not conduct a meta-analysis or establish a relationship between visual impairment and depression in the elderly.
DOI: 10.6084/m9.figshare.7102031
title: A supramolecular look at microenvironmental regulation of limbal epithelial stem cells and the differentiation of their progeny

description: ABSTRACT Various approaches have been taken to improve our knowledge of the microenvironmental regulation of limbal epithelial stem cells. Researchers have extensively investigated the roles of growth factors, survival factors, cytokines, enzymes, and permeable molecules secreted by the limbal cells. However, recent evidence suggests that stem cell fate (i.e., self-renewal or differentiation) can also be influenced by biophysical and mechanical cues related to the supramolecular organization and the liquid crystalline (mesophase) nature of the stromal extracellular matrix. These cues can be sensed by stem cells and transduced into intracellular biochemical and functional responses, a process known as mechanotransduction. The objective of this review is to offer perspectives on the supramolecular microenvironmental regulation of limbal epithelial stem cells and the differentiation of their progeny.
DOI: 10.6084/m9.figshare.7102031.v1
title: A supramolecular look at microenvironmental regulation of limbal epithelial stem cells and the differentiation of their progeny

description: ABSTRACT Various approaches have been taken to improve our knowledge of the microenvironmental regulation of limbal epithelial stem cells. Researchers have extensively investigated the roles of growth factors, survival factors, cytokines, enzymes, and permeable molecules secreted by the limbal cells. However, recent evidence suggests that stem cell fate (i.e., self-renewal or differentiation) can also be influenced by biophysical and mechanical cues related to the supramolecular organization and the liquid crystalline (mesophase) nature of the stromal extracellular matrix. These cues can be sensed by stem cells and transduced into intracellular biochemical and functional responses, a process known as mechanotransduction. The objective of this review is to offer perspectives on the supramolecular microenvironmental regulation of limbal epithelial stem cells and the differentiation of their progeny.
DOI: 10.6084/m9.figshare.7102028
title: Bilateral acute angle closure in a patient with dengue fever: a case report

description: ABSTRACT We report the case of a 46-year-old female patient who presented with bilateral acute angle closure during the course of dengue infection. Dengue diagnosis was confirmed by serological tests. The patient had plateau iris configuration identified by ultrasound biomicroscopy. This is the second reported case with this condition during dengue fever and the first to describe the characteristics of the angle.
DOI: 10.6084/m9.figshare.7102028.v1
title: Bilateral acute angle closure in a patient with dengue fever: a case report

description: ABSTRACT We report the case of a 46-year-old female patient who presented with bilateral acute angle closure during the course of dengue infection. Dengue diagnosis was confirmed by serological tests. The patient had plateau iris configuration identified by ultrasound biomicroscopy. This is the second reported case with this condition during dengue fever and the first to describe the characteristics of the angle.
DOI: 10.6084/m9.figshare.7102019
title: Foliar morphoanatomical plasticity of Smilax campestris (Smilacaceae) in an environmental gradient of restinga, Santa Catarina State, Brazil

description: ABSTRACT In this study, the foliar morphoanatomical plasticity of Smilax campestris (Smilacaceae) was analyzed along an environmental gradient in different restinga formations, in the coastal plain of São Francisco do Sul, Santa Catarina State, Brazil. Twenty individuals were selected by formation, from which 140 leaves were collected for the morphoanatomical characterization. The environmental heterogeneity was characterized by soil nutrition and light radiation. Data were evaluated using ANOVA and PCA. All the leaf traits analyzed, as well as the environmental variables, showed a statistically significant difference among the four restinga formations, with emphasis on the traits of dry mass, fresh mass, leaf area, specific leaf area, abaxial epidermis thickness and leaf density. The main environmental variables were: organic matter, base saturation, sum of bases and magnesium content. The morphoanatomical adjustments of S. campestris in response to different environmental conditions resulted in sclerophyllous leaves, with a pronounced xeromorphic appearance near the sea that gradually becomes less evident within the continent.
DOI: 10.6084/m9.figshare.7102022
title: Preoperative tranilast as adjunctive therapy to primary pterygium surgery with a 1-year follow-up

description: Purpose: To determine the efficacy of tranilast as an adjunctive therapy in conjunctival autograft. Methods: Twenty-nine patients were randomly allocated to the Tranilast Group (n=15) or the Control Group (n=14). The Tranilast Group received a subconjunctival injection of 0.5% tranilast 30 days prior to surgery. Conjunctival autograft was performed in both groups using fibrin sealant and 0.02% subconjunctival mitomycin C at the end of the surgery. After the resection of the pterygium, immunohistochemistry was performed with 100 cells to identify epithelial cells positive for transforming growth factor-β (TGF-β). Subjective symptoms were evaluated using a 5-point scale, and the recurrence rate was assessed. Results: Both groups showed improvements in their symptoms and similar clinical results. Compared with the Control Group, the Tranilast Group failed to show a decreased recurrence rate (p=0.59). However, the number of epithelial cells expressing TGF-β was lower in the Tranilast Group (5 cells; 95% CI: 2.56-13.15; Control Group, 16 cells, 95% CI: 11.53-24.76; p=0.01). Minimal but reversible complications, including glaucoma secondary to corticosteroids and granuloma, occurred during the study. Conclusion: Tranilast was effective in decreasing the number of pterygium epithelial cells expressing TGF-β.
DOI: 10.6084/m9.figshare.7102022.v1
title: Preoperative tranilast as adjunctive therapy to primary pterygium surgery with a 1-year follow-up

description: Purpose: To determine the efficacy of tranilast as an adjunctive therapy in conjunctival autograft. Methods: Twenty-nine patients were randomly allocated to the Tranilast Group (n=15) or the Control Group (n=14). The Tranilast Group received a subconjunctival injection of 0.5% tranilast 30 days prior to surgery. Conjunctival autograft was performed in both groups using fibrin sealant and 0.02% subconjunctival mitomycin C at the end of the surgery. After the resection of the pterygium, immunohistochemistry was performed with 100 cells to identify epithelial cells positive for transforming growth factor-β (TGF-β). Subjective symptoms were evaluated using a 5-point scale, and the recurrence rate was assessed. Results: Both groups showed improvements in their symptoms and similar clinical results. Compared with the Control Group, the Tranilast Group failed to show a decreased recurrence rate (p=0.59). However, the number of epithelial cells expressing TGF-β was lower in the Tranilast Group (5 cells; 95% CI: 2.56-13.15; Control Group, 16 cells, 95% CI: 11.53-24.76; p=0.01). Minimal but reversible complications, including glaucoma secondary to corticosteroids and granuloma, occurred during the study. Conclusion: Tranilast was effective in decreasing the number of pterygium epithelial cells expressing TGF-β.
DOI: 10.6084/m9.figshare.7102016
title: VIOLENT ARRANGEMENTS AND HOPE: HOW THE LANGUAGE OF HUMAN RIGHTS WAS ENACTED AFTER A TERRORIST ATTACK IN FORTALEZA, CE, BRAZIL

description: ABSTRACT This paper describes some forms of resistance to contemporary violent arrangements - understood as the tense relations, in Brazil, between groups of the violent organized crime and between the latter and the public world - which have emerged in the speech of people who survived or were affected by a terrorist attack in the neighborhood of Benfica, in Fortaleza, Ceará, Brazil, occurred in March, 2018. In line with other studies about forms of subjective and collective flourishing in circumstances of violence or political destruction, we will term this form of resistance as 'hope'. By engaging with two interviews conducted with two survivors, a professor, and a human rights' activist, we argue that hope, in these dialogues, amounted to responding to violence not by means of vengeance or extralegal mechanisms of violence but by using tropes that inform the defense of human rights.