cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.12033996
title: Global transcriptome analysis of novel stress associated protein (<i>SAP</i>) genes expression dynamism of combined abiotic stresses in <i>Oryza sativa</i> (L.)

description: Genes encoding proteins with A20/AN1 zinc-finger domains, belonging to the stress associated protein (SAP) gene family, are present in all eukaryotes and play a decisive role in plant response to diverse physiological and molecular activities particularly on biotic and abiotic stresses (AbS). In this first and foremost study, global transcriptome analysis of members of the <i>SAP</i> gene family was carried out in C3 model-<i>Oryza sativa</i> (<i>OsSAP</i>) aiming at the identification of <i>OsSAP</i> genes activated in response to unique or Combined AbS (CAbS). Based on the available spatio-temporal and phytohormonal RNA-Seq expression profile datasets, nine <i>OsSAP</i> genes were filtered out and identified by a differential expression signature noted in various tissues as well as plant hormones. Comparative genome ideogram of <i>OsSAP</i> genes confirmed the orthologous collinearity with C4 panicoid genomes. Interactome of these genes, revealed the molecular cross-talks of <i>OsSAP</i>. Thus, the computational expression signature of <i>OsSAP</i> genes led to a better understanding of gene dynamism in diverse developmental tissues/organs. Transcriptional regulation analysis of key <i>OsSAP</i> genes in response to stress (drought and salinity) suggested the novel role of <i>OsSAP1</i>, <i>OsSAP2</i>, <i>OsSAP5, OsSAP7</i>, <i>OsSAP8</i> and <i>OsSAP11</i> in AbS. Altogether, the study provides deeper insights on molecular characteristics of <i>OsSAP</i> genes, which could be deployed further to decipher their precise functional roles in AbS responses. Communicated by Ramaswamy H. Sarma
DOI: 10.6084/m9.figshare.12033996.v2
title: Global transcriptome analysis of novel stress associated protein (<i>SAP</i>) genes expression dynamism of combined abiotic stresses in <i>Oryza sativa</i> (L.)

description: Genes encoding proteins with A20/AN1 zinc-finger domains, belonging to the stress associated protein (SAP) gene family, are present in all eukaryotes and play a decisive role in plant response to diverse physiological and molecular activities particularly on biotic and abiotic stresses (AbS). In this first and foremost study, global transcriptome analysis of members of the <i>SAP</i> gene family was carried out in C3 model-<i>Oryza sativa</i> (<i>OsSAP</i>) aiming at the identification of <i>OsSAP</i> genes activated in response to unique or Combined AbS (CAbS). Based on the available spatio-temporal and phytohormonal RNA-Seq expression profile datasets, nine <i>OsSAP</i> genes were filtered out and identified by a differential expression signature noted in various tissues as well as plant hormones. Comparative genome ideogram of <i>OsSAP</i> genes confirmed the orthologous collinearity with C4 panicoid genomes. Interactome of these genes, revealed the molecular cross-talks of <i>OsSAP</i>. Thus, the computational expression signature of <i>OsSAP</i> genes led to a better understanding of gene dynamism in diverse developmental tissues/organs. Transcriptional regulation analysis of key <i>OsSAP</i> genes in response to stress (drought and salinity) suggested the novel role of <i>OsSAP1</i>, <i>OsSAP2</i>, <i>OsSAP5, OsSAP7</i>, <i>OsSAP8</i> and <i>OsSAP11</i> in AbS. Altogether, the study provides deeper insights on molecular characteristics of <i>OsSAP</i> genes, which could be deployed further to decipher their precise functional roles in AbS responses. Communicated by Ramaswamy H. Sarma
DOI: 10.6084/m9.figshare.12073392
title: Exploring the interaction of Peloruside-A with drug resistant αβII and αβIII tubulin isotypes in human ovarian carcinoma using a molecular modeling approach

description: Microtubules (MTs) play an essential role in mitosis; hence they are identified as potential targets to design novel anti-mitotic agents. MT’s are composed of α/β-tubulin isotypes that are associated with differential drug-resistant effects against MT-targeting agents. Peloruside-A (PLA) is a potent anti-mitotic agent showing excellent activity against taxol-resistant carcinoma. PLA alters MT dynamics by binding to the ‘non-taxoid’ site of β-tubulin. The abundance of βII and βIII tubulin isotypes in human ovarian carcinoma affects the efficacy of PLA. Nevertheless, the mechanism of PLA resistance due to βII and βIII tubulin isotype is not well understood. Therefore, we investigated the interactions of PLA with αβIIa, αβIIb, and αβIII tubulin isotypes which are predominantly expressed in the human ovarian carcinoma, using a molecular modeling approach. A sequence analysis study shows that the βIII isotype has seven residue variations at the ‘non-taxoid’ site compared to the βIIa and βIIb isotypes. Molecular docking and molecular dynamics simulation revealed that residue variation at the ‘non-taxoid’ site of βIII isotype affect PLA binding. Furthermore, binding energy calculations showed that αβIIa has the highest binding towards PLA, whereas αβIIb and αβIII isotypes shows weaker associations with PLA. Our computational study provides valuable structural and energetic information to increase understanding into the origin of PLA resistance in human ovarian carcinoma and could be helpful to develop potential PLA analogs against specific β-tubulin isotypes expressed in cancer cells. Communicated by Ramaswamy H. Sarma
DOI: 10.6084/m9.figshare.12073392.v1
title: Exploring the interaction of Peloruside-A with drug resistant αβII and αβIII tubulin isotypes in human ovarian carcinoma using a molecular modeling approach

description: Microtubules (MTs) play an essential role in mitosis; hence they are identified as potential targets to design novel anti-mitotic agents. MT’s are composed of α/β-tubulin isotypes that are associated with differential drug-resistant effects against MT-targeting agents. Peloruside-A (PLA) is a potent anti-mitotic agent showing excellent activity against taxol-resistant carcinoma. PLA alters MT dynamics by binding to the ‘non-taxoid’ site of β-tubulin. The abundance of βII and βIII tubulin isotypes in human ovarian carcinoma affects the efficacy of PLA. Nevertheless, the mechanism of PLA resistance due to βII and βIII tubulin isotype is not well understood. Therefore, we investigated the interactions of PLA with αβIIa, αβIIb, and αβIII tubulin isotypes which are predominantly expressed in the human ovarian carcinoma, using a molecular modeling approach. A sequence analysis study shows that the βIII isotype has seven residue variations at the ‘non-taxoid’ site compared to the βIIa and βIIb isotypes. Molecular docking and molecular dynamics simulation revealed that residue variation at the ‘non-taxoid’ site of βIII isotype affect PLA binding. Furthermore, binding energy calculations showed that αβIIa has the highest binding towards PLA, whereas αβIIb and αβIII isotypes shows weaker associations with PLA. Our computational study provides valuable structural and energetic information to increase understanding into the origin of PLA resistance in human ovarian carcinoma and could be helpful to develop potential PLA analogs against specific β-tubulin isotypes expressed in cancer cells. Communicated by Ramaswamy H. Sarma
DOI: 10.34808/q2er-d670
title: The XPS studies revealing the surface chemistry of Cu-Sn-TiO2 nanocomposite coatings

description: The dataset contains the X-Ray Photoelectron Spectroscopy (XPS) data of nanocomposite Cu-Sn-TiO2 coatings electrodeposited from oxalic acid bath containing Cu and Sn salts as well as TiO2 nanoparticles under various treatments: mechanical stirring, ultrasonic or none. The details of the electrodeposition process are presented in the descriptor file attached to the dataset. The measurements are a part of the studies on CuSn coatings formation and their micromechanical, anti-corrosion, and antimicrobial properties. 
The analysis was performed using an Escalab 250Xi system (ThermoFisher Scientific, USA), equipped with a monochromatic AlKa source. The dataset contains files in two formats: VGD - dedicated format to be used with ThermoFisher Avantage software and converted AVG text format.
DOI: 10.34808/9320-0f64
title: The scanning electron microscopy (SEM) studies of heavy boron-doped diamond oxidation under high-temperature

description: The dataset contains the results of scanning electron microscopy (SEM) images of heavy boron-doped diamond (BDD) electrodes subjected to high-temperature oxidation in a furnace at 600 Celsius. The micrographs reveal the material decomposition of BDD grains due to high temperature.
These and similar results were part of the studies described within the manuscript in Materials journal (10.3390/ma13040964) and in Ultramicroscopy journal (10.1016/j.ultramic.2019.01.004)
DOI: 10.34808/1qg7-ad70
title: The BDD electrodes wettability modification by anodic polarization treatment

description: The dataset contains the raw images, photographs obtained for the contact angle measurement at the surface of the boron-doped diamond (BDD) electrode. The measurements were carried out on after potentiodynamic polarization procedure, at various anodic polarization scan range (no polarization - HTBDD; 1.0 V; 1.4 V; 1.9 V; 2.5 V vs Ag|AgCl, scan rate 1 mV/s) in 1M H2SO4 solution. The modification of the contact angle is a derivative of the BDD surface termination oxidation. More detailed information on this study may be found in the manuscript published in Carbon: 10.1016/j.carbon.2015.10.064.
Wettability angle was measured by the sessile drop method (drop volume ∼50 µL) using the self-designed tensiometer system based on B/W CCD camera (Thorlabs, DCU223M, USA).
DOI: 10.34808/v32v-aw37
title: X-ray Photoelectron Spectroscopy studies of laser-induced titania nanotubes

description: This dataset contains the results of high-resolution XPS studies obtained during the formation of the hollow nanopillar arrays through the laser-induced transformation of titania nanotubes. 
The analysis was performed using an Escalab 250Xi system (ThermoFisher Scientific, USA), equipped with a monochromatic AlKa source. More detailed information on this study may be found in the open-access Scientific Reports article by authors: 10.1038/s41598-020-77309-2
The dataset contains the files of the laser-modified sample "F30" and the reference sample prior to the modification. The files are in two formats: VGD - dedicated format to be used with ThermoFisher Avantage software and converted AVG ASCII text files.
DOI: 10.6084/m9.figshare.14332868
title: Supplementary Material for: An Accidental Repetitive 10-Fold Overdose of Sildenafil in a Young Infant with Pulmonary Hypertension

description: Sildenafil is a selective phosphodiesterase type-5 inhibitor that is increasingly used to treat pulmonary hypertension (PH) in neonates. Only little is known about the relation between the dose of sildenafil, plasma concentrations, and the degree of toxicity. Here, we present a young infant with congenital diaphragmatic hernia and PH who received an unintentional 10-fold overdose of oral sildenafil for 6 consecutive days. This overdose, compared to the therapeutic dose, resulted in increased plasma concentrations of sildenafil from 42 to 521 mcg/L and desmethylsildenafil from 81 to 393 mcg/L. However, the high exposure only led to diarrhea, without any other serious adverse events. This case describes the mild symptoms upon an overdose with the role of therapeutic drug monitoring to monitor exposure in relation to symptoms and therewith support clinical decision-making.
DOI: 10.6084/m9.figshare.14332868.v1
title: Supplementary Material for: An Accidental Repetitive 10-Fold Overdose of Sildenafil in a Young Infant with Pulmonary Hypertension

description: Sildenafil is a selective phosphodiesterase type-5 inhibitor that is increasingly used to treat pulmonary hypertension (PH) in neonates. Only little is known about the relation between the dose of sildenafil, plasma concentrations, and the degree of toxicity. Here, we present a young infant with congenital diaphragmatic hernia and PH who received an unintentional 10-fold overdose of oral sildenafil for 6 consecutive days. This overdose, compared to the therapeutic dose, resulted in increased plasma concentrations of sildenafil from 42 to 521 mcg/L and desmethylsildenafil from 81 to 393 mcg/L. However, the high exposure only led to diarrhea, without any other serious adverse events. This case describes the mild symptoms upon an overdose with the role of therapeutic drug monitoring to monitor exposure in relation to symptoms and therewith support clinical decision-making.
DOI: 10.6084/m9.figshare.14332823
title: eams_data.zip

description: <b>Modulation of shelf circulations under multiple river discharges in the East China Sea</b><br>
DOI: 10.34808/0kbc-ny83
title: Complete input data to CFD 3D model of combustion in the large marine 4-stroke engine

description: Input data to CFD and 3D model of combustion process for large marine 4-stroke diesel engine.
Parameters of the engine are presented in https://doi.org/10.1515/pomr-2015-006
Data consist of moving mesh of combustion chamber and solving stering files for AVL Fire Software v.2014 and later.
Results of calculation are validated acording to combustion pressure and oxygen and NOx fraction in the exhaust gas
DOI: 10.34808/7v5s-vx82
title: Low frequency nois of supecapacitor

description: Dataset contains results of low frequency noise observation during discharge of commercially available supercapacitor, type DRL 2.7V 10F, with a nominal capacitance 10 F and a nominal voltage 2.7 V. Supercapacitor was charged to various voltages and discharged through a resistor. In the experiment the 50 Ohm and 200 Ohm resistors were used. The supercapacitor was charged to various voltages from 0,5 V to 2,7 V, which is nominal voltage of this device. The measurement method and measurement setup are described in https://doi.org/10.1515/mms-2017-0059. 
Data is stored in binary files with little-endian byte order (8 bytes per sample, double precision). Single .bin file contains 32 seconds of voltage observation taken with sampling frequency 1024 Hz.  Files contain observations for single experiment are stored in one ZIP archive and numbered sequentially. The electrical signal was amplified before sampled. Signal amplification for each experiment is given in "description.txt" file.
Filename decoding:D4_RRROhm_VVV_NNN.bin
RRR - discharge resistor value in Ohms (50/200), VVV - charging voltage (0V5 -&gt; 0,5 V; 1V0 -&gt; 1,0 V, ...), NNN - sequential file number.
The binary data have to be read as little-endian byte order double precision number.
DOI: 10.48420/14308478
title: STRIDE Research Software Engineering COVID-19 interview study dataset and materials.

description: This dataset contains results from an interview study deployed between April and June 2020 to understand the changing situation in research software engineering work environments as a result of the COVID-19 pandemic. The study took place over an eight-week period, during which 17 self-identified research software engineers (RSEs) recorded their thoughts about the impact of the pandemic on their work and lifestyles. Each weekly entry included a series of questions based on the agile software engineering retrospective, a technique used within agile teams to look back on previous work. The first week followed a basic retrospective format, asking participants to assess what went well and didn’t go well, and to identify areas that could be improved going forward. To encourage ongoing participation, questions in subsequent weeks were adapted from creative retrospective plans designed by agile practitioners. <br>An invitation to take part was issued via various international RSE social media channels in two batches, resulting in 11 participants starting in the week commencing on the 6<sup>th </sup> of April, and six starting in the week of the 20<sup>th</sup> of April. In total, 17 participants responded to the invitation; 15 agreed to participate after the first week. Participants were sent an email each week inviting them to complete a diary entry for a total of eight weeks; data were collected through a survey deployed via JISC’s Online Surveys.<br>The consent form and a pdf of the first week of questions are included in the materials to provide an example of how the survey was administered. The entry week and questions are reported in full in columns A and B in the spreadsheet accordingly. To avoid identification of individuals, demographic information and some contextual information has been redacted. Redactions are indicated by *** in the response.<br>The study was conducted as part of the STRIDE project: https://stride.org.uk.
DOI: 10.48420/14308478.v1
title: STRIDE Research Software Engineering COVID-19 interview study dataset and materials.

description: This dataset contains results from an interview study deployed between April and June 2020 to understand the changing situation in research software engineering work environments as a result of the COVID-19 pandemic. The study took place over an eight-week period, during which 17 self-identified research software engineers (RSEs) recorded their thoughts about the impact of the pandemic on their work and lifestyles. Each weekly entry included a series of questions based on the agile software engineering retrospective, a technique used within agile teams to look back on previous work. The first week followed a basic retrospective format, asking participants to assess what went well and didn’t go well, and to identify areas that could be improved going forward. To encourage ongoing participation, questions in subsequent weeks were adapted from creative retrospective plans designed by agile practitioners. <br>An invitation to take part was issued via various international RSE social media channels in two batches, resulting in 11 participants starting in the week commencing on the 6<sup>th </sup> of April, and six starting in the week of the 20<sup>th</sup> of April. In total, 17 participants responded to the invitation; 15 agreed to participate after the first week. Participants were sent an email each week inviting them to complete a diary entry for a total of eight weeks; data were collected through a survey deployed via JISC’s Online Surveys.<br>The consent form and a pdf of the first week of questions are included in the materials to provide an example of how the survey was administered. The entry week and questions are reported in full in columns A and B in the spreadsheet accordingly. To avoid identification of individuals, demographic information and some contextual information has been redacted. Redactions are indicated by *** in the response.<br>The study was conducted as part of the STRIDE project: https://stride.org.uk.
DOI: 10.5517/ccdc.csd.cc25qv70
title: CCDC 2017952: Experimental Crystal Structure Determination

description: Related Article: Kenta Sato, Masashi Hasegawa, Yuki Nojima, Nobuyuki Hara, Tomohiko Nishiuchi, Yoshitane Imai, Yasuhiro Mazaki|2020|Chem.-Eur.J.|27|1323|doi:10.1002/chem.202004283
DOI: 10.5517/ccdc.csd.cc25xwvv
title: CCDC 2023768: Experimental Crystal Structure Determination

description: Related Article: Laura Bergamonti, Silvia Gentili, Domenico Acquotti, Matteo Tegoni, Pier Paolo Lottici, Claudia Graiff|2020|J.Hazard.Mater.|410|124585|doi:10.1016/j.jhazmat.2020.124585
DOI: 10.5517/ccdc.csd.cc25xwww
title: CCDC 2023769: Experimental Crystal Structure Determination

description: Related Article: Laura Bergamonti, Silvia Gentili, Domenico Acquotti, Matteo Tegoni, Pier Paolo Lottici, Claudia Graiff|2020|J.Hazard.Mater.|410|124585|doi:10.1016/j.jhazmat.2020.124585
DOI: 10.25505/fiz.icsd.cc1xpzwg
title: CSD 1778807: Experimental Crystal Structure Determination

description: Related Article: Ma Huiyuan, Wang Xiaodan, Dong Baoxia, Li Chunxiang, Wu Lizhou|2008|Cryst.Res.Technol.|43|28|doi:10.1002/crat.200710986
DOI: 10.25505/fiz.icsd.cc1xpbjg
title: CSD 1778176: Experimental Crystal Structure Determination

description: Related Article: V. Smetana, V. Babizhet'sky, G.V. Vajenine, A. Simon|2006|Inorg.Chem.|45|10786|doi:10.1021/ic0613816
DOI: 10.25505/fiz.icsd.cc1xpwr7
title: CSD 1778710: Experimental Crystal Structure Determination

description: Related Article: Jiang Hailong, Ma En, Mao Jiang Gao|2007|Inorg.Chem.|46|7012|doi:10.1021/ic700793n
DOI: 10.25505/fiz.icsd.cc1xwy0r
title: CSD 1784515: Experimental Crystal Structure Determination

description: Related Article: S. Lupart, G. Gregori, J. Maier, W. Schnick|2012|J.Am.Chem.Soc.|134|10132|doi:10.1021/ja302255d
DOI: 10.25505/fiz.icsd.cc1xmys8
title: CSD 1776851: Experimental Crystal Structure Determination

description: Related Article: B. Muktha, T.N. Guru Row|2007|Struct.Chem.|18|195|doi:10.1007/s11224-006-9093-2
DOI: 10.25505/fiz.icsd.cc1xtnky
title: CSD 1782331: Experimental Crystal Structure Determination

description: Related Article: A. Haberer, R. Kaindl, O. Oeckler, H. Huppertz|2010|J.Solid State Chem.|183|1970|doi:10.1016/j.jssc.2010.06.019
DOI: 10.5517/ccdc.csd.cc26qjhz
title: CCDC 2047441: Experimental Crystal Structure Determination

description: Related Article: Tomoyuki Yanagi, Takayuki Tanaka, Hideki Yorimitsu|2021|Chemical Science|12|2784|doi:10.1039/D1SC00044F
DOI: 10.25505/fiz.icsd.cc27k10w
title: CSD 2071947: Experimental Crystal Structure Determination

description: Related Article: Zhihui NI|2021|ICSD Communication|||
DOI: 10.25505/fiz.icsd.cc27kk5k
title: CSD 2072448: Experimental Crystal Structure Determination

description: Related Article: Brian W. Skelton|2021|ICSD Communication|||
DOI: 10.5281/zenodo.4603020
title: Data for publication: "Zooplanktivore fish body growth responses to browning-induced light limitation vary over ontogeny, but not with fish density"

description: Data for publication: "Zooplanktivore fish body growth responses to browning-induced light limitation vary over ontogeny, but not with fish density" in "Ecology of Freshwater Fish".
DOI: 10.5281/zenodo.4603019
title: Data for publication: "Zooplanktivore fish body growth responses to browning-induced light limitation vary over ontogeny, but not with fish density"

description: Data for publication: "Zooplanktivore fish body growth responses to browning-induced light limitation vary over ontogeny, but not with fish density" in "Ecology of Freshwater Fish".
DOI: 10.5281/zenodo.4626756
title: Trialstreamer data

description: Trialstreamer annotated collection of RCTs. This respository contains baseline files (large), and subsequent updates (daily for PubMed, weekly for ICTRP).
DOI: 10.5281/zenodo.4643647
title: Dataset from Biagioli V, Belloni S, Albanesi B, Piredda A, Caruso R. Comment on "The experience on coronavirus disease 2019 and cancer from an oncology hub institution in Milan, Lombardy Region" and reflections from the Italian Association of Oncology Nurses. Eur J Cancer. 2020 Aug;135:8-10. doi: 10.1016/j.ejca.2020.05.022. Epub 2020 Jun 4. PMID: 32521294; PMCID: PMC7269936.

description: Dataset from the Letter to the Editor Biagioli V, Belloni S, Albanesi B, Piredda A, Caruso R. Comment on "The experience on coronavirus disease 2019 and cancer from an oncology hub institution in Milan, Lombardy Region" and reflections from the Italian Association of Oncology Nurses. Eur J Cancer. 2020 Aug;135:8-10. doi: 10.1016/j.ejca.2020.05.022. Epub 2020 Jun 4. PMID: 32521294; PMCID: PMC7269936.