cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5517/ccdc.csd.cc1n08zx
title: CCDC 1519619: Experimental Crystal Structure Determination

description: Related Article: Hong-Tao Xue, Gabriele Boschetto, Michal Krompiec, Graham E. Morse, Fu-Ling Tang, Chris-Kriton Skylaris|2017|Phys.Chem.Chem.Phys.(PCCP)|19|5617|doi:10.1039/C6CP08165G
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc1n09kj
title: CCDC 1519637: Experimental Crystal Structure Determination

description: Related Article: Rong-Yan Wang, Xiao Zhang, Qi-Sheng Huo, Jie-Hui Yu, Ji-Qing Xu|2017|RSC Advances|7|19073|doi:10.1039/C6RA27510A
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc1n09lk
title: CCDC 1519638: Experimental Crystal Structure Determination

description: Related Article: Rong-Yan Wang, Xiao Zhang, Qi-Sheng Huo, Jie-Hui Yu, Ji-Qing Xu|2017|RSC Advances|7|19073|doi:10.1039/C6RA27510A
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc1n09ml
title: CCDC 1519639: Experimental Crystal Structure Determination

description: Related Article: Rong-Yan Wang, Xiao Zhang, Qi-Sheng Huo, Jie-Hui Yu, Ji-Qing Xu|2017|RSC Advances|7|19073|doi:10.1039/C6RA27510A
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc1n09nm
title: CCDC 1519640: Experimental Crystal Structure Determination

description: Related Article: Rong-Yan Wang, Xiao Zhang, Qi-Sheng Huo, Jie-Hui Yu, Ji-Qing Xu|2017|RSC Advances|7|19073|doi:10.1039/C6RA27510A
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc1n09qp
title: CCDC 1519642: Experimental Crystal Structure Determination

description: Related Article: Mir Abolfazl Naziri, Ertan Sahin, Nurgul Seferoglu, Behrouz Shaabani|2018|J.Coord.Chem.|71|89|doi:10.1080/00958972.2018.1432857
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc1mgyjk
title: CCDC 1503919: Experimental Crystal Structure Determination

description: Related Article: Jie Yang, Xu Zhen, Bin Wang, Xuming Gao, Zichun Ren, Jiaqiang Wang, Yujun Xie, Jianrong Li, Qian Peng, Kanyi Pu, Zhen Li|2018|Nat.Commun.|9|840|doi:10.1038/s41467-018-03236-6
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc1n09rq
title: CCDC 1519643: Experimental Crystal Structure Determination

description: Related Article: Jianlin Yang, Ming Zhang, Peng Wang, Wenjuan Liu, Ruwei Shen|2018|Chin.Chem.Lett.|29|524|doi:10.1016/j.cclet.2017.09.001
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc1n09sr
title: CCDC 1519644: Experimental Crystal Structure Determination

description: Related Article: Simon Remy,  Florent Olivon,  Sandy Desrat,  Florent Blanchard,  Véronique Eparvier,  Pieter Leyssen,  Johan Neyts,  Fanny Roussi,  David Touboul,  and Marc Litaudon|2018|J.Nat.Prod.|81|901|doi:10.1021/acs.jnatprod.7b01025
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc1n09ts
title: CCDC 1519645: Experimental Crystal Structure Determination

description: Related Article: Simon Remy,  Florent Olivon,  Sandy Desrat,  Florent Blanchard,  Véronique Eparvier,  Pieter Leyssen,  Johan Neyts,  Fanny Roussi,  David Touboul,  and Marc Litaudon|2018|J.Nat.Prod.|81|901|doi:10.1021/acs.jnatprod.7b01025
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc1n09wv
title: CCDC 1519647: Experimental Crystal Structure Determination

description: Related Article: Simon Remy,  Florent Olivon,  Sandy Desrat,  Florent Blanchard,  Véronique Eparvier,  Pieter Leyssen,  Johan Neyts,  Fanny Roussi,  David Touboul,  and Marc Litaudon|2018|J.Nat.Prod.|81|901|doi:10.1021/acs.jnatprod.7b01025
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc1n09xw
title: CCDC 1519648: Experimental Crystal Structure Determination

description: Related Article: Simon Remy,  Florent Olivon,  Sandy Desrat,  Florent Blanchard,  Véronique Eparvier,  Pieter Leyssen,  Johan Neyts,  Fanny Roussi,  David Touboul,  and Marc Litaudon|2018|J.Nat.Prod.|81|901|doi:10.1021/acs.jnatprod.7b01025
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc1n09yx
title: CCDC 1519649: Experimental Crystal Structure Determination

description: Related Article: Simon Remy,  Florent Olivon,  Sandy Desrat,  Florent Blanchard,  Véronique Eparvier,  Pieter Leyssen,  Johan Neyts,  Fanny Roussi,  David Touboul,  and Marc Litaudon|2018|J.Nat.Prod.|81|901|doi:10.1021/acs.jnatprod.7b01025
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc1n09zy
title: CCDC 1519650: Experimental Crystal Structure Determination

description: Related Article: Alexander W. Schuppe, Timothy R. Newhouse|2017|J.Am.Chem.Soc.|139|631|doi:10.1021/jacs.6b12268
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc1n0b00
title: CCDC 1519651: Experimental Crystal Structure Determination

description: Related Article: Alexander W. Schuppe, Timothy R. Newhouse|2017|J.Am.Chem.Soc.|139|631|doi:10.1021/jacs.6b12268
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc1n0b11
title: CCDC 1519652: Experimental Crystal Structure Determination

description: Related Article: Benita Barton, Eric C. Hosten, Daniel V. Jooste|2017|Tetrahedron|73|2662|doi:10.1016/j.tet.2017.03.049
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc1n0b22
title: CCDC 1519653: Experimental Crystal Structure Determination

description: Related Article: Benita Barton, Eric C. Hosten, Daniel V. Jooste|2017|Tetrahedron|73|2662|doi:10.1016/j.tet.2017.03.049
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc1n0b33
title: CCDC 1519654: Experimental Crystal Structure Determination

description: Related Article: Benita Barton, Eric C. Hosten, Daniel V. Jooste|2017|Tetrahedron|73|2662|doi:10.1016/j.tet.2017.03.049
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc1n0b44
title: CCDC 1519655: Experimental Crystal Structure Determination

description: Related Article: Takumi Fujino,  Tomoaki Hinoue,  Yoshinosuke Usuki,  Tetsuya Satoh|2016|Org.Lett.|18|5688|doi:10.1021/acs.orglett.6b02919
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc1n0b55
title: CCDC 1519656: Experimental Crystal Structure Determination

description: Related Article: Takumi Fujino,  Tomoaki Hinoue,  Yoshinosuke Usuki,  Tetsuya Satoh|2016|Org.Lett.|18|5688|doi:10.1021/acs.orglett.6b02919
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc1n0b88
title: CCDC 1519659: Experimental Crystal Structure Determination

description: Related Article: Philipp Bertocco, Janis Derendorf, Carsten Jenne, Christoph Kirsch|2017|Inorg.Chem.|56|3459|doi:10.1021/acs.inorgchem.6b03006
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc1n0b99
title: CCDC 1519660: Experimental Crystal Structure Determination

description: Related Article: Philipp Bertocco, Janis Derendorf, Carsten Jenne, Christoph Kirsch|2017|Inorg.Chem.|56|3459|doi:10.1021/acs.inorgchem.6b03006
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc1n0bff
title: CCDC 1519664: Experimental Crystal Structure Determination

description: Related Article: Hasan Mtiraoui, Kevin Renault, Morgane Sanselme, Moncef Msaddek, Pierre-Yves Renard, Cyrille Sabot|2017|Org.Biomol.Chem.|15|7474|doi:10.1039/C7OB90126G
description: Related Article: Hasan Mtiraoui, Kevin Renault, Morgane Sanselme, Moncef Msaddek, Pierre-Yves Renard, Cyrille Sabot|2017|Org.Biomol.Chem.|15|3060|doi:10.1039/C7OB00205J
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.15468/dl.bptsuk
title: Occurrence Download

description: A dataset containing 1 species occurrences available in GBIF matching the query:
{
 "and" : [
 "GadmGid is CHN.28_1",
 "TaxonKey is Leymus arjinshanicus"
 ]
}

 The dataset includes 1 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0054368-251009101135966/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.v232p5
title: Occurrence Download

description: A dataset containing 148 species occurrences available in GBIF matching the query:
{
 "and" : [
 {
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen)"
 ]
 }
 }
 ]
 },
 "TaxonKey is one of (Townsendia condensata Parry)"
 ]
}

 The dataset includes 148 records from 16 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0014997-241126133413365/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.pmwvgf
title: Occurrence Download

description: A dataset containing 482702 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Continent is South America",
 "OccurrenceStatus is Present",
 "TaxonKey is Apidae"
 ]
}

 The dataset includes 482702 records from 273 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0014989-241126133413365/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.22654291
title: Data from: "AP-1/c-Fos supports SIV and HIV-1 latency in CD4 T-cells infected in vivo"

description:  Seurat objects containing the scRNA-seq data from the two rhesus macaques in "AP-1/c-Fos supports SIV and HIV-1 latency in CD4 T-cells infected <em>in vivo</em>"
DOI: 10.6084/m9.figshare.22654291.v1
title: Data from: "AP-1/c-Fos supports SIV and HIV-1 latency in CD4 T-cells infected in vivo"

description:  Seurat objects containing the scRNA-seq data from the two rhesus macaques in "AP-1/c-Fos supports SIV and HIV-1 latency in CD4 T-cells infected <em>in vivo</em>"
DOI: 10.15468/dl.tgj9ak
title: Occurrence Download

description: A dataset containing 1083 species occurrences available in GBIF matching the query:
{
 "and" : [
 {
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen)"
 ]
 }
 }
 ]
 },
 "TaxonKey is one of (Thymophylla tenuiloba (DC.) Small)"
 ]
}

 The dataset includes 1083 records from 65 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0014998-241126133413365/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.rhpmmh
title: Occurrence Download

description: A dataset containing 297 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Vespa soror Buysson, 1905)",
 "HasCoordinate is true"
 ]
}

 The dataset includes 297 records from 7 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0014999-241126133413365/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.27953115
title: <b>table</b>

description: Basketball, Musculoskeletal Manipulations, Postural balance, Exercise,
DOI: 10.6084/m9.figshare.27953115.v1
title: <b>table</b>

description: Basketball, Musculoskeletal Manipulations, Postural balance, Exercise,
DOI: 10.15468/dl.a29g3q
title: Occurrence Download

description: A dataset containing 14420 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Gobius niger Linnaeus, 1758",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 14420 records from 151 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0015001-241126133413365/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.7274/27923100
title: Development of Hsp90 C-Terminal Modulators: To Treat Two Diseases with One Target

description: The modulation of the heat shock protein 90 (Hsp90) C-terminal domain has emerged as a promising area of investigation due to its critical role in the chaperone cycle and protein homeostasis. Hsp90 is a ubiquitous molecular chaperone involved in the folding, stabilization, and activation of a wide array of client proteins, many of which are key regulators of cellular signaling pathways. Traditional approaches to targeting Hsp90 have focused on its N-terminal ATP-binding domain, but these strategies have often been limited by dose-limiting toxicity caused by induction of the heat shock response (HSR). Recent research has shifted toward the C-terminal domain of Hsp90, which presents a unique set of regulatory features and potential therapeutic advantages. Targeting the C-terminal domain can effectively disrupt the chaperone cycle, leading to selective degradation of oncogenic client proteins without induction of the HSR typically associated with N-terminal inhibitors.
This dissertation explores the structure activity relationship (SAR) on the Hsp90 C-terminal modulators, investigating the size and nature of Hsp90 C-terminal domain. Analysis of SAR via cell viability assays have led to the identification of some key features associated with C-terminal domain modulation. Moreover, we have developed small molecules that target the Hsp90 C-terminal domain, demonstrating potential as therapeutic agents in cancer and/or neurodegenerative diseases. These compounds exhibit a distinct mechanism of action, providing a new avenue for therapeutic intervention with potentially reduced side effects compared to conventional Hsp90 inhibitors. In summary, this work enhances our insights into the Hsp90 C-terminal domain's binding mechanisms and highlights its potential as a target for novel therapeutic strategies.
DOI: 10.7274/27923100.v1
title: Development of Hsp90 C-Terminal Modulators: To Treat Two Diseases with One Target

description: The modulation of the heat shock protein 90 (Hsp90) C-terminal domain has emerged as a promising area of investigation due to its critical role in the chaperone cycle and protein homeostasis. Hsp90 is a ubiquitous molecular chaperone involved in the folding, stabilization, and activation of a wide array of client proteins, many of which are key regulators of cellular signaling pathways. Traditional approaches to targeting Hsp90 have focused on its N-terminal ATP-binding domain, but these strategies have often been limited by dose-limiting toxicity caused by induction of the heat shock response (HSR). Recent research has shifted toward the C-terminal domain of Hsp90, which presents a unique set of regulatory features and potential therapeutic advantages. Targeting the C-terminal domain can effectively disrupt the chaperone cycle, leading to selective degradation of oncogenic client proteins without induction of the HSR typically associated with N-terminal inhibitors.
This dissertation explores the structure activity relationship (SAR) on the Hsp90 C-terminal modulators, investigating the size and nature of Hsp90 C-terminal domain. Analysis of SAR via cell viability assays have led to the identification of some key features associated with C-terminal domain modulation. Moreover, we have developed small molecules that target the Hsp90 C-terminal domain, demonstrating potential as therapeutic agents in cancer and/or neurodegenerative diseases. These compounds exhibit a distinct mechanism of action, providing a new avenue for therapeutic intervention with potentially reduced side effects compared to conventional Hsp90 inhibitors. In summary, this work enhances our insights into the Hsp90 C-terminal domain's binding mechanisms and highlights its potential as a target for novel therapeutic strategies.
DOI: 10.57745/j9p5cs
title: PFAS_SOEREPRO_2024_Database.tab

description: :unav
DOI: 10.57745/suumi1
title: PFAS_SOEREPRO_2024_Database_metadata.xlsx

description: :unav
DOI: 10.15468/dl.m7hyf3
title: Occurrence Download

description: A dataset containing 27590 species occurrences available in GBIF matching the query:
{
 "and" : [
 {
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen)"
 ]
 }
 }
 ]
 },
 "TaxonKey is one of (Petrorhagia saxifraga (L.) Link)"
 ]
}

 The dataset includes 27590 records from 329 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0015002-241126133413365/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.