cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.24167775
title: Visual attention-guided augmented representation of geographic scenes: A case of bridge stress visualization

description: Efficient geovisualization is beneficial for understanding geospatial phenomena, an important research direction for GISers and Cartographers. However, the current research on geovisualization overemphasizes the visual effects while neglecting the prominent representation of crucial information and failing to consider the user's cognitive workload of information processing. Following the laws of visual perception of the human eyes, this article proposes a visual attention-guided augmented representation approach of geographic scenes that involves area of interest computation, background simplification, and compound graphic variables. Finally, we select bridge stress visualization as a case study for experimental analysis. The experi?mental results of eye-tracking show that augmented representation could draw the participants' attention to areas of interest in a short time, increasing their duration of fixations and the accuracy of completing given tasks. These findings suggest that our approach can enhance geographic scenes' cognitive efficiency, offers a new idea for the theoretical studies of geovisualization, and holds promising potential for broader application in various geographical phenomena visualization.
DOI: 10.25582/data.2022-10.2621471/2285866
title: Data for EMSL Project 51834 from October 2022
DOI: 10.6084/m9.figshare.7390634
title: Analysis of BMSCs-intervened viscoelasticity of sciatic nerve in rats with chronic alcoholic intoxication

description: Abstract Purpose: To investigate the impact of bone mesenchymal stem cells (BMSCs) intervention on the viscoelasticity of sciatic nerve in rats with chronic alcohol intoxication (CAI). Methods: The CAI rat models were prepared, divided into model groups, and treated with either BMSCs or basic fibroblast growth factor (bFGF). Then the rats underwent electrophysiological test and the serum levels of malondialdehyde (MDA), superoxide dismutase (SOD), and metallothionein (MT) were measured. Histological observation, stress relaxation test, and creep test were performed for the sciatic nerve of the CAI model in each group. Results: The MDA level of group BMSC was significantly lower (p&lt;0.05) than that of groups MOD (the CIA model) and bFGF. The SOD and MT levels were higher in group BMSC than in groups MOD and bFGF (p&lt;0.05). The motor nerve conduction velocity and amplitude were higher in group BMSC than in groups MOD and bFGF (p&lt;0.05). The amounts of 7200s stress reduction and 7200 s strain increase of the sciatic nerve in group BMSC were greater than those in groups bFGF and MOD (p&lt;0.05). Conclusion: Bone mesenchymal stem cells can improve the metabolism of free radicals, restore the tissue morphology and viscoelasticity of the chronic alcohol intoxication animal model, and positively affect the repairing of the injured sciatic nerve.
DOI: 10.25582/data.2022-09.2609285/2285867
title: Data for EMSL Project 51834 from September 2022
DOI: 10.25582/data.2022-10.2621596/2285868
title: Data for EMSL Project 51834 from October 2022
DOI: 10.25582/data.2021-10.2368034/2285869
title: Data for EMSL Project 51834 from October 2021
DOI: 10.25582/data.2021-09.2328558/2285870
title: Data for EMSL Project 51834 from September 2021
DOI: 10.25582/data.2022-01.2417410/2285871
title: Data for EMSL Project 51834 from January 2022
DOI: 10.25582/data.2022-04.2479161/2285872
title: Data for EMSL Project 51834 from April 2022
DOI: 10.25582/data.2021-12.2389923/2285873
title: Data for EMSL Project 51834 from December 2021
DOI: 10.25582/data.2021-09.2321566/2285874
title: Data for EMSL Project 51834 from September 2021
DOI: 10.25582/data.2021-11.2387788/2285875
title: Data for EMSL Project 51834 from November 2021
DOI: 10.25582/data.2021-08.2304657/2285876
title: Data for EMSL Project 51834 from August 2021
DOI: 10.25582/data.2022-10.2623211/2285877
title: Data for EMSL Project 51834 from October 2022
DOI: 10.25582/data.2021-09.2327286/2285878
title: Data for EMSL Project 51834 from September 2021
DOI: 10.25582/data.2022-10.2617732/2285879
title: Data for EMSL Project 51834 from October 2022
DOI: 10.25582/data.2021-10.2360955/2285880
title: Data for EMSL Project 51834 from October 2021
DOI: 10.25582/data.2021-11.2375285/2285881
title: Data for EMSL Project 51834 from November 2021
DOI: 10.25582/data.2022-09.2608796/2285882
title: Data for EMSL Project 51834 from September 2022
DOI: 10.25582/data.2021-10.2368121/2285883
title: Data for EMSL Project 51834 from October 2021
DOI: 10.6084/m9.figshare.7390772
title: Analysis of the application values of different combination schemes of liquid-based cytology and high-risk human papilloma virus test in the screening of high-grade cervical lesions

description: The aim of this study was to explore the value of different combination schemes of liquid-based cytology (LBC) and high-risk human papilloma virus (HPV) test in the screening of high-grade (≥CIN 2) cervical lesions. From 5727 women who had undergone examinations with LBC and high-risk HPV test, 1884 patients with positive results of either or both LBC and HPV test were included in this study and underwent cervical biopsy. Based on the pathological examination results, comparisons of the assessment indicators of all diagnostic tests were made, and the application values of LBC and high-risk HPV test and different combination schemes of the two in the screening of high-grade (≥CIN II) cervical lesions were estimated. Compared with the single test method, the sensitivity and negative predictive value of the combination scheme of LBC+HPV (with one positive result) were increased significantly (98.7% and 99.7%), but the specificity (60.8%) and accuracy rate (65.4%) dropped significantly (P&lt;0.05). The sensitivity of LBC+HPV (with two positive results) was the lowest (80.7%), but the specificity and accuracy rate were the highest (83.5% and 83.1%, P&lt;0.05). Z test showed that differences in the screening efficiency of four schemes were not statistically significant (P&gt;0.05). Both LBC and HPV test were effective methods in the screening of high-grade cervical lesions; combination of the two tests did not improve the screening efficiency, but the scheme of LBC+HPV (with two positive results) significantly increased the sensitivity and negative predictive value, which was of better cost-benefit value.
DOI: 10.25582/data.2021-11.2387016/2285884
title: Data for EMSL Project 51834 from November 2021
DOI: 10.25582/data.2021-11.2387281/2285885
title: Data for EMSL Project 51834 from November 2021
DOI: 10.25582/data.2021-08.2305243/2285886
title: Data for EMSL Project 51834 from August 2021
DOI: 10.25582/data.2021-11.2387656/2285887
title: Data for EMSL Project 51834 from November 2021
DOI: 10.25582/data.2021-08.2304262/2285888
title: Data for EMSL Project 51834 from August 2021
DOI: 10.25582/data.2022-10.2622385/2285889
title: Data for EMSL Project 51834 from October 2022
DOI: 10.6084/m9.figshare.14728642
title: Additional file 2 of A systematic review of natural language processing applied to radiology reports

description: Additional file 2. Individual properties for every publication.
DOI: 10.25582/data.2022-01.2417415/2285890
title: Data for EMSL Project 51834 from January 2022
DOI: 10.6084/m9.figshare.14206586
title: Trehalose causes low-grade lysosomal stress to activate TFEB and the autophagy-lysosome biogenesis response

description: The autophagy-lysosome system is an important cellular degradation pathway that recycles dysfunctional organelles and cytotoxic protein aggregates. A decline in this system is pathogenic in many human diseases including neurodegenerative disorders, fatty liver disease, and atherosclerosis. Thus there is intense interest in discovering therapeutics aimed at stimulating the autophagy-lysosome system. Trehalose is a natural disaccharide composed of two glucose molecules linked by a ɑ-1,1-glycosidic bond with the unique ability to induce cellular macroautophagy/autophagy and with reported efficacy on mitigating several diseases where autophagy is dysfunctional. Interestingly, the mechanism by which trehalose induces autophagy is unknown. One suggested mechanism is its ability to activate TFEB (transcription factor EB), the master transcriptional regulator of autophagy-lysosomal biogenesis. Here we describe a potential mechanism involving direct trehalose action on the lysosome. We find trehalose is endocytically taken up by cells and accumulates within the endolysosomal system. This leads to a low-grade lysosomal stress with mild elevation of lysosomal pH, which acts as a potent stimulus for TFEB activation and nuclear translocation. This process appears to involve inactivation of MTORC1, a known negative regulator of TFEB which is sensitive to perturbations in lysosomal pH. Taken together, our data show the trehalose can act as a weak inhibitor of the lysosome which serves as a trigger for TFEB activation. Our work not only sheds light on trehalose action but suggests that mild alternation of lysosomal pH can be a novel method of inducing the autophagy-lysosome system. <b>Abbreviations:</b> ASO: antisense oligonucleotide; AU: arbitrary units; BMDM: bone marrow-derived macrophages; CLFs: crude lysosomal fractions; CTSD: cathepsin D; LAMP: lysosomal associated membrane protein; LIPA/LAL: lipase A, lysosomal acid type; MAP1LC3: microtubule-associated protein 1 light chain 3; MFI: mean fluorescence intensity; MTORC1: mechanistic target of rapamycin kinase complex 1; pMAC: peritoneal macrophages; SLC2A8/GLUT8: solute carrier family 2, (facilitated glucose transporter), member 8; TFEB: transcription factor EB; TMR: tetramethylrhodamine; TREH: trehalase
DOI: 10.6084/m9.figshare.14728642.v1
title: Additional file 2 of A systematic review of natural language processing applied to radiology reports

description: Additional file 2. Individual properties for every publication.
DOI: 10.25582/data.2021-09.2322408/2285891
title: Data for EMSL Project 51834 from September 2021
DOI: 10.25582/data.2022-09.2609283/2285892
title: Data for EMSL Project 51834 from September 2022
DOI: 10.6084/m9.figshare.7390865
title: Apoptotic mechanisms in rabbits with blast-induced acute lung injury

description: Abstract Purpose: To investigate the apoptotic mechanisms in rabbits with blast-induced acute lung injury (ALI). Methods: A total of 40 rabbits were randomly divided into a blank control group (A, n=10) and an experimental group (EXP, n=30). Explosion-induced chest-ALI models were prepared and sampled at different time points (4, 12, and 24h after modeling, T1-T3) to test the lung dry weight/wet weight ratio (W/D) and arterial oxygen pressure (PaO2), apoptosis of lung tissue by the TUNEL assay, and Caspase-3, Bax, and Bcl-2 levels by immunohistochemical analysis. Furthermore, lung tissue was sampled to observe pathological morphology by microscopy. Results: Under a light microscope, Group EXP exhibited obvious edema in the pulmonary interstitial substance and alveoli, a large number of red blood cells, inflammatory cells, and serous exudation in the alveolar cavity, as well as thickening of the pulmonary interstitial fluid. Compared to Group A, the W/D ratio was significantly increased in Group EXP (P&lt;0.01), while PaO2 was significantly reduced (P&lt;0.01). The apoptosis index was significantly increased (P&lt;0.01), and caspase-3 and Bax/Bcl-2 levels were increased (P&lt;0.01). Conclusion: Apoptosis plays an important role in the occurrence and development of acute lung injury in rabbits by participating in lung injury and promoting the progression of ALI.
DOI: 10.25582/data.2022-04.2479174/2285893
title: Data for EMSL Project 51834 from April 2022
DOI: 10.25582/data.2022-01.2417248/2285894
title: Data for EMSL Project 51834 from January 2022
DOI: 10.25582/data.2021-08.2305279/2285895
title: Data for EMSL Project 51834 from August 2021
DOI: 10.25582/data.2021-09.2321503/2285896
title: Data for EMSL Project 51834 from September 2021
DOI: 10.25582/data.2022-10.2617214/2285897
title: Data for EMSL Project 51834 from October 2022
DOI: 10.25582/data.2021-11.2387408/2285898
title: Data for EMSL Project 51834 from November 2021
DOI: 10.25582/data.2022-10.2616403/2285899
title: Data for EMSL Project 51834 from October 2022
DOI: 10.25582/data.2021-10.2368058/2285900
title: Data for EMSL Project 51834 from October 2021
DOI: 10.6084/m9.figshare.7915181.v1
title: Additional file 2: of Reprogramming histone modification patterns to coordinate gene expression in early zebrafish embryos

description: Table S1. Pairwise dissimilarities for each stage in zebrafish (XLSX 9 kb)
DOI: 10.25582/data.2021-08.2303959/2285901
title: Data for EMSL Project 51834 from August 2021
DOI: 10.6084/m9.figshare.15253308.v1
title: Additional file 1 of Comprehensive genomic survey, structural classification and expression analysis of C2H2-type zinc finger factor in wheat (Triticum aestivum L.)

description: Additional file 1: Table S1. Classification of the 457 Triticum aestivum C2H2-ZFPs according to the organization of their contained C2H2 fingers. Table S2. List of 204 Triticum aestivum C2H2-ZFP genes and their related information. Table S3. One-to-one orthologous relationships between T.aestivum and T.aestivum, T.aestivum and A.tauschii, T.aestivum and B.distachyon, T.aestivum and Rice, T.aestivum and Arabidopsis. Table S4. Primers used for qRT-PCR. Table S5. Expression profiles of T. aestivum C2H2-ZFP genes.
DOI: 10.25582/data.2022-10.2615606/2285902
title: Data for EMSL Project 51834 from October 2022
DOI: 10.6084/m9.figshare.15253308
title: Additional file 1 of Comprehensive genomic survey, structural classification and expression analysis of C2H2-type zinc finger factor in wheat (Triticum aestivum L.)

description: Additional file 1: Table S1. Classification of the 457 Triticum aestivum C2H2-ZFPs according to the organization of their contained C2H2 fingers. Table S2. List of 204 Triticum aestivum C2H2-ZFP genes and their related information. Table S3. One-to-one orthologous relationships between T.aestivum and T.aestivum, T.aestivum and A.tauschii, T.aestivum and B.distachyon, T.aestivum and Rice, T.aestivum and Arabidopsis. Table S4. Primers used for qRT-PCR. Table S5. Expression profiles of T. aestivum C2H2-ZFP genes.
DOI: 10.25582/data.2022-10.2620108/2285903
title: Data for EMSL Project 51834 from October 2022
DOI: 10.25582/data.2021-12.2410937/2285904
title: Data for EMSL Project 51834 from December 2021
DOI: 10.25582/data.2021-08.2304293/2285905
title: Data for EMSL Project 51834 from August 2021
DOI: 10.25582/data.2022-10.2615771/2285906
title: Data for EMSL Project 51834 from October 2022
DOI: 10.25582/data.2021-08.2303798/2285907
title: Data for EMSL Project 51834 from August 2021
DOI: 10.6084/m9.figshare.7915205.v1
title: Additional file 5: of Reprogramming histone modification patterns to coordinate gene expression in early zebrafish embryos

description: Table S4. Enriched GO and INTERPRO domains for active gene group in zebrafish. (XLSX 15 kb)
DOI: 10.25582/data.2021-12.2404779/2285908
title: Data for EMSL Project 51834 from December 2021
DOI: 10.6084/m9.figshare.6887423
title: PTENα regulates mitophagy and maintains mitochondrial quality control

description: PTEN plays an important role in tumor suppression, and PTEN family members are involved in multiple biological processes in various subcellular locations. Here we report that PTENα, the first identified PTEN isoform, regulates mitophagy through promotion of PARK2 recruitment to damaged mitochondria. We show that PTENα-deficient mice exhibit accumulation of cardiac mitochondria with structural and functional abnormalities, and PTENα-deficient mouse hearts are more susceptible to injury induced by isoprenaline and ischemia-reperfusion. Mitochondrial clearance by mitophagy is also impaired in PTENα-deficient cardiomyocytes. In addition, we found PTENα physically interacts with the E3 ubiquitin ligase PRKN, which is an important mediator of mitophagy. PTENα binds PRKN through the membrane binding helix in its N-terminus, and promotes PRKN mitochondrial translocation through enhancing PRKN self-association in a phosphatase-independent manner. Loss of PTENα compromises mitochondrial translocation of PRKN and resultant mitophagy following mitochondrial depolarization. We propose that PTENα functions as a mitochondrial quality controller that maintains mitochondrial function and cardiac homeostasis. <b>Abbreviations:</b> BECN1 beclin 1; CCCP carbonyl cyanide m-chlorophenylhydrazone; FBXO7 F-box protein 7; FS fraction shortening; HSPA1L heat shock protein family A (Hsp70) member 1 like; HW: BW heart weight:body weight ratio; I-R ischemia-reperfusion; ISO isoprenaline; MAP1LC3/LC3 microtubule associated protein 1 light chain 3; MBH membrane binding helix; MFN1 mitofusin 1; MFN2 mitofusin 2; Nam nicotinamide; TMRM tetramethylrhodamine ethyl ester; WGA wheat germ agglutinin
DOI: 10.25582/data.2021-11.2387369/2285909
title: Data for EMSL Project 51834 from November 2021
DOI: 10.25582/data.2021-11.2376178/2285910
title: Data for EMSL Project 51834 from November 2021
DOI: 10.25582/data.2021-09.2322380/2285911
title: Data for EMSL Project 51834 from September 2021
DOI: 10.25582/data.2021-09.2322340/2285912
title: Data for EMSL Project 51834 from September 2021
DOI: 10.25582/data.2021-11.2387658/2285913
title: Data for EMSL Project 51834 from November 2021
DOI: 10.25582/data.2021-11.2389635/2285914
title: Data for EMSL Project 51834 from November 2021
DOI: 10.25582/data.2021-08.2305255/2285915
title: Data for EMSL Project 51834 from August 2021
DOI: 10.25582/data.2021-09.2327635/2285916
title: Data for EMSL Project 51834 from September 2021
DOI: 10.25582/data.2021-10.2348006/2285917
title: Data for EMSL Project 51834 from October 2021
DOI: 10.25582/data.2021-11.2380514/2285918
title: Data for EMSL Project 51834 from November 2021
DOI: 10.25582/data.2022-01.2417421/2285919
title: Data for EMSL Project 51834 from January 2022
DOI: 10.25582/data.2021-09.2328631/2285920
title: Data for EMSL Project 51834 from September 2021
DOI: 10.25582/data.2022-10.2615879/2285921
title: Data for EMSL Project 51834 from October 2022
DOI: 10.25582/data.2022-10.2621364/2285922
title: Data for EMSL Project 51834 from October 2022
DOI: 10.25582/data.2021-12.2401298/2285923
title: Data for EMSL Project 51834 from December 2021
DOI: 10.6084/m9.figshare.25158014
title: Supplementary Material for: A Prognostic Model for Survival in Patients with Gastric Signet-Ring Cell Carcinoma

description: Background: The objective of our study was to develop a nomogram to predict overall survival (OS) and cancer-specific survival (CSS) in patients with gastric signet ring cell carcinoma (GSRCC).
Patients and Methods: A total of 3408 GSRCC patients between 1975 and 2017 were screened from the Surveillance, Epidemiology, and End Results (SEER) database and randomly divided into training and validation cohorts. Univariate and multivariate Cox analyses were conducted to identify independent prognostic factors for the construction of a nomogram. The performance of the model was then assessed by the concordance index (C-index), calibration plot and area under the receiver operating characteristic (ROC) curve (AUC). Then, the novel nomogram was further assessed by 64 GSRCC patients from our hospital as the external cohort.
Results: We identified age, tumor lymph node metastasis (TNM) staging system, surgery and chemotherapy as significant independent elements of prognosis. On this basis, a nomogram was constructed, with a C-index of OS in the training and validation cohorts of 0.763 (95% CI: 0.751–0.774) and 0.766 (95% CI: 0.748–0.784) and a C-index of CSS of 0.765 (95% CI: 0.753–0.777) and 0.773 (95% CI: 0.755–0.791), respectively. The AUCs of the nomogram for predicting 2- and 5-year OS were 0.848 and 0.885, respectively, and those for predicting CSS were 0.854 and 0.899, respectively, demonstrating the excellent predictive value of the constructed nomogram compared to the traditional AJCC staging system. Similar results were also observed in both the internal and external validation sets.
Conclusion: The nomogram provided an accurate tool to predict OS and CSS in patients with GSRCC, which can assist clinicians in making predictions about individual patient survival.
DOI: 10.25582/data.2021-11.2387284/2285924
title: Data for EMSL Project 51834 from November 2021
DOI: 10.25582/data.2021-09.2320307/2285925
title: Data for EMSL Project 51834 from September 2021
DOI: 10.25582/data.2022-04.2479160/2285926
title: Data for EMSL Project 51834 from April 2022
DOI: 10.25582/data.2022-09.2609474/2285927
title: Data for EMSL Project 51834 from September 2022
DOI: 10.25582/data.2021-12.2411421/2285928
title: Data for EMSL Project 51834 from December 2021
DOI: 10.25582/data.2022-04.2479180/2285929
title: Data for EMSL Project 51834 from April 2022
DOI: 10.25582/data.2021-11.2375865/2285930
title: Data for EMSL Project 51834 from November 2021
DOI: 10.25582/data.2022-04.2479144/2285931
title: Data for EMSL Project 51834 from April 2022
DOI: 10.25582/data.2021-10.2369925/2285932
title: Data for EMSL Project 51834 from October 2021
DOI: 10.25582/data.2021-12.2399791/2285933
title: Data for EMSL Project 51834 from December 2021
DOI: 10.25582/data.2021-09.2317883/2285934
title: Data for EMSL Project 51834 from September 2021
DOI: 10.25582/data.2022-10.2621267/2285935
title: Data for EMSL Project 51834 from October 2022
DOI: 10.25582/data.2021-12.2390574/2285936
title: Data for EMSL Project 51834 from December 2021
DOI: 10.25582/data.2021-08.2305321/2285937
title: Data for EMSL Project 51834 from August 2021
DOI: 10.25582/data.2022-09.2612219/2285938
title: Data for EMSL Project 51834 from September 2022
DOI: 10.25582/data.2022-09.2608823/2285939
title: Data for EMSL Project 51834 from September 2022
DOI: 10.25582/data.2021-11.2387955/2285940
title: Data for EMSL Project 51834 from November 2021
DOI: 10.25582/data.2022-10.2613658/2285941
title: Data for EMSL Project 51834 from October 2022
DOI: 10.25582/data.2021-10.2363575/2285942
title: Data for EMSL Project 51834 from October 2021
DOI: 10.25582/data.2022-10.2621199/2285943
title: Data for EMSL Project 51834 from October 2022
DOI: 10.6084/m9.figshare.7915298.v1
title: Additional file 5: of Integrated analysis of lncRNA and mRNA repertoires in Marekâ s disease infected spleens identifies genes relevant to resistance

description: DE protein coding genes, known lncRNAs and putative lncRNAs in 17 samples. (XLSX 237 kb)
DOI: 10.25582/data.2021-10.2363865/2285944
title: Data for EMSL Project 51834 from October 2021
DOI: 10.25582/data.2022-10.2617964/2285945
title: Data for EMSL Project 51834 from October 2022
DOI: 10.25582/data.2022-10.2621354/2285946
title: Data for EMSL Project 51834 from October 2022
DOI: 10.25582/data.2021-12.2399862/2285947
title: Data for EMSL Project 51834 from December 2021
DOI: 10.25582/data.2021-08.2305302/2285948
title: Data for EMSL Project 51834 from August 2021
DOI: 10.25582/data.2021-12.2399650/2285949
title: Data for EMSL Project 51834 from December 2021
DOI: 10.25582/data.2021-09.2318857/2285950
title: Data for EMSL Project 51834 from September 2021
DOI: 10.25582/data.2022-09.2606403/2285951
title: Data for EMSL Project 51834 from September 2022
DOI: 10.25582/data.2021-08.2304587/2285952
title: Data for EMSL Project 51834 from August 2021
DOI: 10.25582/data.2021-11.2387625/2285953
title: Data for EMSL Project 51834 from November 2021
DOI: 10.25582/data.2022-01.2417431/2285954
title: Data for EMSL Project 51834 from January 2022
DOI: 10.25582/data.2021-09.2322495/2285955
title: Data for EMSL Project 51834 from September 2021
DOI: 10.25582/data.2022-10.2617959/2285956
title: Data for EMSL Project 51834 from October 2022
DOI: 10.25582/data.2021-09.2322522/2285957
title: Data for EMSL Project 51834 from September 2021
DOI: 10.25582/data.2022-10.2620112/2285958
title: Data for EMSL Project 51834 from October 2022