cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.30845072.v1
title: Supplementary Material for: Extracellular vesicle-based urinary proteomic signatures predict remission and relapse in primary membranous nephropathy

description: Background: Primary membranous nephropathy (PMN) is one of the leading causes of nephrotic syndrome in adults, but reliable prognostic assessment tools remain limited. Although traditional clinical parameters and serum anti-PLA2R antibodies constitute cornerstones of prognosis assessment, they fail to fully capture the heterogeneity of PMN treatment responses. Identification of multidimensional prognostic risk factors facilitates further guidance for treatment in PMN patients. This study aimed to identify novel urinary protein signatures predictive of clinical remission and delineate molecular subtypes associated with relapse.
Methods: We performed quantitative proteomic profiling on extracellular vesicles (uEVs) isolated from baseline urine samples of 86 biopsy-confirmed PMN patients using nanoflow high-performance liquid chromatography–tandem mass spectrometry (nanoHPLC-MS/MS). The primary endpoints were clinical remission (complete or partial remission) and time to clinical remission. A prognostic model was developed by screening 101 machine learning algorithms, with the final risk score derived from a random survival forest and stepwise Cox regression, internally validated via bootstrap resampling. Relapse-associated molecular subtypes were identified using non-negative matrix factorization (NMF).
Results: During a median follow-up of 8 months (IQR: 3.4-18.5), 76.1% of patients achieved remission, with a median time to remission of 11.2 months (95%CI: 6.2-18.0). The four-protein risk model (PON1, ACTBL2, RDX, TPP1) effectively stratified patients into high- and low-risk groups (Harrell's C-index = 0.729). The combined model integrating this proteomic signature with clinical features (anti-PLA2R Ab, age, eGFR) demonstrated superior predictive performance (Harrell's C-index = 0.744) compared to the clinical-feature-only model (Harrell's C-index = 0.636). To improve clinical applicability, we developed a web-based interactive Shiny application for PMN patients individualized risk prediction. Additionally, proteomic clustering identified three distinct molecular subtypes (PMN1-3), with subtype PMN2 emerging as an independent predictor of relapse (OR = 10.26, 95% CI: 1.68–81.97; P &lt; 0.05).
Conclusion: The combined model incorporating four non-invasive urinary proteomic signature and clinical characteristics significantly improved performance of predicting clinical remission in PMN patients compared to the clinical-feature-only model. Furthermore, molecular subtyping of the urinary proteome can identify patients at high risk for relapse. These findings provide a foundation for integrating advanced proteomics into personalized prognostic assessment for PMN patients, pending external validation in larger cohorts.
DOI: 10.6084/m9.figshare.30845075
title: Supplementary Material for: A Multi-national Survey on Immunosuppressive Regimens and Mycophenolate Monitoring Practices After Kidney Transplantation

description: Abstract: 
Background: Kidney transplantation (KT) offers substantial improvements in both survival and quality of life compared to dialysis in patients with end-stage kidney disease. However, the success of KT is critically dependent on effective immunosuppression. There has been improvement in short-term graft survival outcomes, but chronic rejection and cumulative drug toxicities continue to present significant challenges. Regarding immunosuppression monitoring strategies, calcineurin inhibitor trough concentrations is a standard practice, but for the mycophenolate mofetil (MMF), fixed dosing remains widespread despite considerable evidence supporting for dose optimization based on mycophenolic acid (MPA) area under the curve (AUC) monitoring. To elucidate current immunosuppressive practices and mycophenolate dosing strategies, we conducted a survey of multiple transplant centers in India, Australia, and New Zealand. 
Methods: An internet-based questionnaire was sent via professional societies and direct correspondence to practitioners across Australia, New Zealand and India.
Results: We received responses from 142 centers across the three regions. Most respondents (90%) reported use of antibody induction therapy in standard risk recipients. Maintenance immunosuppression overwhelmingly involved “triple therapy” with tacrolimus (98%), mycophenolate (78% as mycophenolate mofetil), long-term corticosteroid continuation (96%). Overall, 78% reported never using MPA concentrations to guide management, though with geographic differences: 90% of respondents from India reported never measuring MPA, compared to only 32% from Australia and New Zealand (p&lt;0.001). Major reasons for not measuring MPA given were difficulty in attaining MPA concentrations (56%), cost (33%), and uncertainty around techniques to assess exposure and concentration targets (36%). Only a minority (11%) of respondents questioned the clinical value of monitoring in clinical care.
Conclusion: Across distinct geographic regions, immunosuppression regimen including tacrolimus, MMF and long-term corticosteroids in standard risk kidney transplant recipients was homogenous. MPA concentration measurement to guide therapy is rarely used in India, though not uncommon across Australia and New Zealand at least in specific circumstances. Overcoming practical barriers and ensuring accessible clinical guidance may provide opportunities to improve the uptake of MPA monitoring
DOI: 10.6084/m9.figshare.30845075.v1
title: Supplementary Material for: A Multi-national Survey on Immunosuppressive Regimens and Mycophenolate Monitoring Practices After Kidney Transplantation

description: Abstract: 
Background: Kidney transplantation (KT) offers substantial improvements in both survival and quality of life compared to dialysis in patients with end-stage kidney disease. However, the success of KT is critically dependent on effective immunosuppression. There has been improvement in short-term graft survival outcomes, but chronic rejection and cumulative drug toxicities continue to present significant challenges. Regarding immunosuppression monitoring strategies, calcineurin inhibitor trough concentrations is a standard practice, but for the mycophenolate mofetil (MMF), fixed dosing remains widespread despite considerable evidence supporting for dose optimization based on mycophenolic acid (MPA) area under the curve (AUC) monitoring. To elucidate current immunosuppressive practices and mycophenolate dosing strategies, we conducted a survey of multiple transplant centers in India, Australia, and New Zealand. 
Methods: An internet-based questionnaire was sent via professional societies and direct correspondence to practitioners across Australia, New Zealand and India.
Results: We received responses from 142 centers across the three regions. Most respondents (90%) reported use of antibody induction therapy in standard risk recipients. Maintenance immunosuppression overwhelmingly involved “triple therapy” with tacrolimus (98%), mycophenolate (78% as mycophenolate mofetil), long-term corticosteroid continuation (96%). Overall, 78% reported never using MPA concentrations to guide management, though with geographic differences: 90% of respondents from India reported never measuring MPA, compared to only 32% from Australia and New Zealand (p&lt;0.001). Major reasons for not measuring MPA given were difficulty in attaining MPA concentrations (56%), cost (33%), and uncertainty around techniques to assess exposure and concentration targets (36%). Only a minority (11%) of respondents questioned the clinical value of monitoring in clinical care.
Conclusion: Across distinct geographic regions, immunosuppression regimen including tacrolimus, MMF and long-term corticosteroids in standard risk kidney transplant recipients was homogenous. MPA concentration measurement to guide therapy is rarely used in India, though not uncommon across Australia and New Zealand at least in specific circumstances. Overcoming practical barriers and ensuring accessible clinical guidance may provide opportunities to improve the uptake of MPA monitoring
DOI: 10.5281/zenodo.17874891
title: Coherent Spin Dynamics in Magnesium-Dependent ATPase: A Theoretical Limit Analysis of the Magnetic Isotope Effect
DOI: 10.5281/zenodo.17874892
title: Coherent Spin Dynamics in Magnesium-Dependent ATPase: A Theoretical Limit Analysis of the Magnetic Isotope Effect
DOI: 10.15468/dl.bjrxwh
title: Occurrence Download

description: A dataset containing 1246 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Philippines",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Rattus everetti"
 ]
}

 The dataset includes 1246 records from 13 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0043458-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.2npd44
title: Occurrence Download

description: A dataset containing 145481 species occurrences available in GBIF matching the query:
{
 "and" : [
 "SpeciesKey is one of (Antrostomus vociferus)",
 "BasisOfRecord is one of (Human Observation, Observation, Occurrence evidence)",
 "Year is greater than or equal to 1951",
 "Year is less than or equal to 2024",
 "Month is greater than or equal to April",
 "Month is less than or equal to July",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present"
 ]
}

 The dataset includes 145481 records from 17 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0043416-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.k5nzw2
title: Occurrence Download

description: A dataset containing 2039 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Strychnos innocua",
 "Continent is Africa"
 ]
}

 The dataset includes 2039 records from 104 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0043461-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.4rwuep
title: Occurrence Download

description: A dataset containing 7690 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON ((-108.273484 37.312529, -108.318416 37.362430, -108.383497 37.362430, -108.338538 37.312529, -108.273484 37.312529))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "Year is greater than or equal to 2015",
 "Year is less than or equal to 2025"
 ]
}

 The dataset includes 7690 records from 6 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0043462-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.j9b9r5
title: Occurrence Download

description: A dataset containing 52 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Eunereis patagonica",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 52 records from 7 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0043463-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.ex5grh
title: Occurrence Download

description: A dataset containing 14049512 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON((61.52487 35.25806,62.13574 32.8192,65.43525 30.98288,64.25106 30.30649,61.1454 30.71859,59.8759 29.24475,61.67247 27.61076,60.74092 25.57456,61.68271 24.80799,65.41545 24.6437,67.90727 25.52982,68.39312 27.68685,70.49363 28.57444,72.44407 32.8567,80.98744 27.14283,86.16975 25.62307,89.04903 26.0095,88.74933 24.82891,90.52724 24.3422,90.06478 23.29551,91.03887 20.66572,93.42061 17.87605,93.1616 15.96719,93.89526 15.18054,95.83251 16.49895,95.81423 18.88373,96.39316 18.47345,98.87368 18.96896,101.47837 20.55262,102.27374 21.94828,100.49257 22.85578,100.53278 23.67343,103.96621 24.93764,104.54136 25.56759,104.73085 26.17354,104.10241 27.30708,105.00753 29.39687,104.11397 30.60069,105.42037 32.20441,106.1748 34.7684,103.30227 38.41545,100.08066 39.85855,93.00629 39.97377,89.9109 39.03537,88.85681 38.17749,89.10603 37.31957,84.21138 36.22857,80.10264 36.84447,78.05782 36.35705,75.71181 38.18624,72.78709 38.03729,72.40386 39.0425,70.94208 39.27737,68.69605 37.98985,66.20038 38.42204,64.59397 37.89534,61.52487 35.25806),(95.12017 22.31185,95.43108 21.76189,95.15338 20.81699,95.12017 22.31185))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Aves"
 ]
}

 The dataset includes 14049512 records from 122 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0043417-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.5ectrn
title: Occurrence Download

description: A dataset containing 12743 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Danaus plexippus plexippus",
 "Year 1900-2025"
 ]
}

 The dataset includes 12743 records from 46 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0043460-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.2rjyp7
title: Occurrence Download

description: A dataset containing 41028 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Aves",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "Geometry POLYGON ((-67.56404 10.29258, -67.57412 10.29258, -67.57304 10.28444, -67.58312 10.28444, -67.58205 10.27631, -67.6022 10.27631, -67.60328 10.28444, -67.61336 10.28444, -67.61659 10.30886, -67.62667 10.30886, -67.62775 10.317, -67.6479 10.317, -67.64359 10.28444, -67.63351 10.28444, -67.62922 10.25189, -67.63929 10.25189, -67.63822 10.24376, -67.6483 10.24376, -67.64616 10.22748, -67.626 10.22748, -67.62493 10.21934, -67.60478 10.21934, -67.60371 10.21121, -67.59363 10.21121, -67.5915 10.19493, -67.58142 10.19493, -67.58036 10.18679, -67.56021 10.18679, -67.56127 10.19493, -67.54112 10.19493, -67.53104 10.19493, -67.53211 10.20307, -67.52203 10.20307, -67.5231 10.21121, -67.49287 10.21121, -67.4918 10.20307, -67.48173 10.20307, -67.47535 10.15425, -67.4552 10.15425, -67.45414 10.14611, -67.43399 10.14611, -67.43717 10.17052, -67.42709 10.17052, -67.42816 10.17866, -67.41808 10.17866, -67.41914 10.18679, -67.42922 10.18679, -67.43028 10.19493, -67.44036 10.19493, -67.44249 10.21121, -67.45256 10.21121, -67.45683 10.24376, -67.46691 10.24376, -67.46798 10.25189, -67.47805 10.25189, -67.47699 10.24376, -67.48706 10.24376, -67.48599 10.23562, -67.51622 10.23562, -67.51729 10.24376, -67.5576 10.24376, -67.55867 10.25189, -67.56875 10.25189, -67.5709 10.26817, -67.56082 10.26817, -67.56297 10.28444, -67.55289 10.28444, -67.55827 10.32514, -67.56835 10.32514, -67.56404 10.29258))",
 "Year is greater than or equal to 2010",
 "Year is less than or equal to 2025"
 ]
}

 The dataset includes 41028 records from 3 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0043464-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.zszrwd
title: Occurrence Download

description: A dataset containing 32 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen)"
 ]
 }
 },
 "TaxonKey is Eleginus nawaga"
 ]
}

 The dataset includes 32 records from 5 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0043465-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.17874898
title: هم ارزی تابع موج شرودینگر و میدان تنش حجمی

description: چارچوب دینامیک حجمی مقاوم به عنوان بسط حقیقی و مکانیکی 

مکانیک کوانتومی در نظر گرفته میشود. رفتار کوانتومی ذرات، پدیدهای نوظهور از نوسانات

هندسی ساختار بنیادی فضا-زمان است که توسط میدان تنش حجمی حاکمیت میشود
DOI: 10.5281/zenodo.17874899
title: هم ارزی تابع موج شرودینگر و میدان تنش حجمی

description: چارچوب دینامیک حجمی مقاوم به عنوان بسط حقیقی و مکانیکی 

مکانیک کوانتومی در نظر گرفته میشود. رفتار کوانتومی ذرات، پدیدهای نوظهور از نوسانات

هندسی ساختار بنیادی فضا-زمان است که توسط میدان تنش حجمی حاکمیت میشود
DOI: 10.5281/zenodo.17874488
title: Data on cellular mechanical properties
DOI: 10.5281/zenodo.17874489
title: Data on cellular mechanical properties
DOI: 10.15468/dl.64au9e
title: Occurrence Download

description: A dataset containing 6 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Neanthes abyssorum",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 6 records from 3 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0043470-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.vb27rp
title: Occurrence Download

description: A dataset containing 33 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Philippines",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Rattus norvegicus"
 ]
}

 The dataset includes 33 records from 4 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0043467-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.ekufez
title: Occurrence Download

description: A dataset listing the 1 species recorded in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON((100.10278 0.86261,100.70046 -0.7376,103.72746 -0.42913,103.16833 1.26742,101.43311 2.07684,100.10278 0.86261))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Aedes aegypti"
 ]
}

 The dataset's 1 records were derived from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0043450-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.hyhfvz
title: Occurrence Download

description: A dataset containing 2776 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON ((-106.916191 37.267031, -106.962774 37.319506, -107.031203 37.319506, -106.984591 37.267031, -106.916191 37.267031))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "Year is greater than or equal to 2015",
 "Year is less than or equal to 2025"
 ]
}

 The dataset includes 2776 records from 4 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0043471-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.wwds8g
title: Occurrence Download

description: A dataset containing 5932 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Strychnos spinosa",
 "Continent is Africa"
 ]
}

 The dataset includes 5932 records from 153 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0043469-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.bdbp6x
title: Occurrence Download

description: A dataset containing 2984 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Continent is Asia",
 "Country is Philippines",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Rousettus amplexicaudatus",
 "Year 1000-2025"
 ]
}

 The dataset includes 2984 records from 19 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0043468-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.17874692
title: JRC-Multi-Modal Retinal Vessel Segmentation

description: Existing retinal vessel segmentation datasets are mostly fundus images. We release this multi-modal retinal vessel segmentation dataset with our paper "Universal Vessel Segmentation for Multi-Modality Retinal Images" (IEEE Trans. Image Processing, vol.34, pp.7903-7918, 2025) to facilitate the study of vessel segmentation in multi-modal retinal imaging. 

The dataset has three subdatasets: JRCFA, JRCFAF and JRCIR, for the Fluorescence Angiography (FA), Fundus AutoFluorescence (FAF) and Infrard Reflectance (IR) modalities, respectively. Each dataset contains 40 images with high-quality vessel annotations by retina experts in the Jacobs Retina Center (JRC) in University of California, San Diego.
DOI: 10.5281/zenodo.17874693
title: JRC-Multi-Modal Retinal Vessel Segmentation

description: Existing retinal vessel segmentation datasets are mostly fundus images. We release this multi-modal retinal vessel segmentation dataset with our paper "Universal Vessel Segmentation for Multi-Modality Retinal Images" (IEEE Trans. Image Processing, vol.34, pp.7903-7918, 2025) to facilitate the study of vessel segmentation in multi-modal retinal imaging. 

The dataset has three subdatasets: JRCFA, JRCFAF and JRCIR, for the Fluorescence Angiography (FA), Fundus AutoFluorescence (FAF) and Infrard Reflectance (IR) modalities, respectively. Each dataset contains 40 images with high-quality vessel annotations by retina experts in the Jacobs Retina Center (JRC) in University of California, San Diego.