cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.23599305.v1
title: 01 Neonatal Hypernatremic Dehydration in Breastfed Neonates: A Prospective Study Unmasking the Influences of Breastfeeding Practices and Early Weight Monitoring

description: descriptive data for a prospective study
DOI: 10.6084/m9.figshare.14279820.v1
title: Lisdexamfetamine dimesylate in the treatment of attention-deficit/hyperactivity disorder: pharmacokinetics, efficacy and safety in children and adolescents

description: Background Psychostimulants (methylphenidate and amphetamines) are considered first-line therapy for attention-deficit/hyperactivity disorder (ADHD). Lisdexamfetamine dimesylate (LDX) is a new psychostimulant approved for the treatment of ADHD in Brazil. The pharmacologically active fraction, d-amphetamine, is gradually released by hydrolysis of the LDX prodrug. Objectives To perform a systematic review of the literature of the efficacy and safety of LDX in the treatment of ADHD in children and adolescents. Methods Medline/PubMed searches for “d-amfetamine”, “lisdexamfetamine” and “lisdexamfetamine dimesylate” were conducted including articles available from January 2000 to November 2013. Additional references were identified using references listed in those articles. Further data on LDX were requested from its manufacturer. Results Thirty-one papers were found related to ADHD treatment in children and adolescents. Discussion The therapeutic benefits of LDX in children with ADHD are achieved as early as 1.5 hours after its administration and last for up to 13 hours, with efficacy comparable or superior to that of other available psychostimulants. The literature also reports efficacy in long-term treatment, with safety and tolerability profiles comparable to those of other stimulants used for the treatment of ADHD. Most of the adverse events associated with LDX are considered to be mild or moderate in severity, with the most common being loss of appetite and insomnia.
DOI: 10.6084/m9.figshare.25902520.v1
title: Supplementary Material for: Exploring the mechanism of cardiorenal protection with finerenone based on network pharmacology

description: Introduction: Large prospective trials have demonstrated that finerenone could reduce the risk of cardiovascular death and progression of renal failure among patients with chronic kidney disease (CKD) associated heart failure (HF) and/or type 2 diabetes mellitus (T2DM). The aim of this study was to explore the molecular mechanism of finerenone in the treatment of cardiorenal diseases through network pharmacology.
Methods: The STITH, SwissTargetPrediction, PharmMapper, DrugBank and ChEMBL databases were used to screen the targets of finerenone. The diseases-related targets were retrieved from the DisGeNET, GeneCards, CTD, OMIM and MalaCards databases. The protein-protein interaction (PPI) network was conducted with STRING database and Cytoscape software. The clusterProfiler R package was used to perform Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis. The interactions of key targets and finerenone were analyzed by molecular docking in Autodock software. Diabetes mellitus was induced by intraperitoneal injection of streptozotocin. Histopathology of myocardial and renal tissues were observed by hematoxylin-eosin (HE) staining, and detection of protein expressions was conducted using western blotting.
Results: A total of 111 potential cardiorenal targets of finerenone were identified. The main mechanisms of action may be associated with lipid and atherosclerosis, fluid shear stress and atherosclerosis, AGE-RAGE signaling pathway in diabetic complications and diabetic cardiomyopathy. The hub targets demonstrated by the PPI network were CASP3, ALB, MMP9, EGFR, ANXA5, IGF1, SRC, TNFRSF1A, IL2 and PPARG, and the docking results suggested that finerenone could bind to these targets with high affinities. HE staining revealed the cardiorenal protection of finerenone on diabetic mice. In addition, the protein expressions of CASP3 and EGFR were increased while ALB was decreased in myocardial and renal tissues in diabetic mice compared with control mice, which were reversed by finerenone.
Conclusion: This study suggested that finerenone exerts cardiorenal benefits through multiple targets and pathways.
DOI: 10.6084/m9.figshare.13169300.v1
title: Code Availability

description: Example of code to demonstrate how the dataset can be accessed and how to visualize some signals. It is only required to have Matlab® software to run this example.
DOI: 10.6084/m9.figshare.28850855.v1
title: Prediction uploaded on April 23 regarding the outcome of the Bologna/Empoli on April 24

description: Further details about the study are available at the following links:<br>https://osf.io/pcwah<br>https://osf.io/xsb9t
DOI: 10.6084/m9.figshare.28124051.v1
title: Changes in perturbation-correlation moving-window two-dimensional correlation spectroscopy of dissolved organic matter induced by dam regulation in a river-type reservoir

description: <b>Background: </b>Water levels in reservoirs are regulated by dams and thus affects the fate of dissolved organic matter(DOM). For more effective water management and natural watershed conservation, the correlation between dam regulation and DOM changes urgently needs to be explained. According to the regulation rules of Shuikou Reservoir dam, the monitoring times were determined to be September 2021, November 2021, January 2022 and May 2022, and the sampling sites covered Shili'an, Yangkeng, Liujia Bridge, Youxi reservoir entrance (downstream), Gutian Huangtian, Gutian Huangtian (downstream), Bay mouth, Xiongjiang River in Minqing, and Front of Shuikou Reservoir dam. Basic water quality parameters, such as temperature, pH, dissolved oxygen (DO), dissolved total nitrogen (DTN), total phosphorus (TP), dissolved organic carbon (DOC), NH<sub>4</sub><sup>+</sup>, NO<sub>3</sub><sup>-</sup>, turbidity, conductivity (us), as well as the components and concentrations of DOM, were collected at the time and space defined above.<b>Methods: </b>In this study, in-situ monitoring, field sampling, perturbation-correlation moving-window two-dimensional (PCMW2D) correlation spectroscopy technology and statistical methods were used orderly.<b>Technique</b><b>: </b>Perturbation-correlation moving-window two-dimensional (PCMW2D) correlation spectroscopy technology was employed to analyze the DOM fluorescence components. Mantel tests were used to statistically evaluate the relationships between DOM fluorescence components and water quality parameters, as well as indicators of organic pollutants.
DOI: 10.6084/m9.figshare.27629220.v1
title: 玉潭油藏表层沉积物正烷烃和碳氮同位素

description: 本研究研究了山区储层沉积物中有机碳 （OC） 的来源和移动及其在碳循环中的作用。研究人员发现，大多数 OC 来自外部来源，包括污水 （33.1%）、植物 （27.1%） 和土壤 （19.9%），其中超过 70% 由植物衍生材料组成。农业和城市化等人类活动对 OC 动力学有很大影响，而水库在管理其运输和储存方面起着至关重要的作用。这些发现加深了我们对农业流域碳储量的理解，并为山区水资源管理和生态保护提供了指导。
DOI: 10.6084/m9.figshare.17158742.v1
title: Mouse Whole Heart Optical Mapping Data

description: All data are provided in .mat format, and organised so that each folder contains an individual experiment (i.e. whole heart or isolated atrium). All PCLs are within single experimental files. .txt are also provided that contain suggested setting for use in ElectroMap, and regions of interest. Filenames include animal ID and intervention.
DOI: 10.6084/m9.figshare.736505.v2
title: Maintaining Processes and Strategies

description: The importance of software maintenance during the life-cycle of software system cannot be over emphasized. The maintenance tasks were focused on delivering system improvements, fixing software defects and preventing software problems from happening. The International Organization for Standardization (ISO) provides guidance for the maintenance of software. The basis for Maintenances Process and its activities comes from the definition of ISO/IEC 12207. It defines the activities and tasks of software maintenance, and provides maintenance planning requirements. This process also includes the migration and retirement of the software. While ISO/IEC 12207 describes the process of what activities and tasks to do to provide guidance to Maintenance Process, ISO/IEC 14764 provides guidance on the management of how to perform the Maintenance Process. There are several models and approaches of how to perform software maintenance process. Organizations should seek to adopt maintenance strategies depending on their business’ need and, of course, capabilities. IT-manager should examine the key elements of their software structure beforehand implementing software maintenance process. This paper aimed to describe ISO/IEC 14764 which defines a clear emphasis on software maintenance process. In this study, I will also examine some of the software maintenance strategies/process that are used by organization and determine if there was improvement in the competitive measures of cost, quality and productivity.
DOI: 10.6084/m9.figshare.21532389.v1
title: Supplementary Material for: A Novel Mask with Selective Ports for Inflow and Outflow Reduces CO<sub>2</sub> Rebreathing during Non-Invasive Ventilation: A Physiological Study in Healthy Volunteers

description: <b><i>Background:</i></b> CO<sub>2</sub> rebreathing is one of the risks associated with noninvasive ventilation (NIV), possibly contributing to failure. In a bench study, we showed that a novel mask design, with separate limbs for inflow and outflow gases, significantly reduced CO<sub>2</sub> rebreathing in different ventilation settings. <b><i>Objectives:</i></b> The study aimed to test whether a new mask design could 1) reduce CO<sub>2</sub> rebreathing in healthy volunteers during NIV (phase 1) and 2) reduce minute ventilation (phase 2). <b><i>Materials and Methods:</i></b> Healthy volunteers were randomly assigned to NIV using two masks in a crossover design: a traditional single-limb mask for inflow and outflow gases and a mask with two separated limbs. In phase 1, six ventilation settings were tested for each mask: CPAP (PEEP 5 cmH<sub>2</sub>O) and pressure support ventilation (PSV, PS Level 5 cmH<sub>2</sub>O) using a mechanical ventilator with a bias flow of 8 or 20 L/min; free-flow CPAP (PEEP 5 cmH<sub>2</sub>O) with 60 or 90 L/min of gas flow. A nasal cannula was inserted in one nostril of the volunteers and connected to a CO<sub>2</sub> gas analyzer to measure CO<sub>2</sub> during the respiratory cycle. In phase 2, volunteers underwent a prolonged time of ventilation in CPAP 90 L/min and PSV with 20 L/min of bias flow. During free-flow CPAP, electrical impedance tomography was used to record the change in impedance during tidal breathing and then estimate tidal volume. <b><i>Results:</i></b> Ten healthy adults were enrolled in phase 1, and 8 volunteers in phase 2. CO<sub>2</sub> during inspiration was significantly lower in each setting with the two-limb versus the one-limb mask (<i>p</i> &lt; 0.001). The maximum CO<sub>2</sub> reduction was observed in the continuous-flow CPAP settings. EtCO<sub>2</sub> was lower with the two-limb mask compared to the one-limb mask (<i>p</i> &lt; 0.001). However, no difference in minute ventilation was observed between the two masks. <b><i>Conclusion:</i></b> The new mask design with two ports for inhaled and exhaled gases reduced the amount of CO<sub>2</sub> rebreathing in all tested ventilation settings. The CO<sub>2</sub> rebreathing reduction did not decrease minute ventilation in healthy volunteers.
DOI: 10.6084/m9.figshare.25539763.v1
title: Supplementary Material for: Tongue Pressure Resistance Training for Post-Stroke Dysphagia: A Case Study

description: ABSTRACT
Purpose: The purpose of this study was to explore the effect of a lingual resistance training protocol on the swallowing function of an individual presenting with dysphagia and reduced tongue pressures following a supratentorial ischemic stroke. 
Methods: A study involving a lingual resistance training protocol with videofluoroscopy to measure outcomes comparing different parameters to ASPEKT normative reference values at three timepoints: baseline (VFSS A), following a 4-week lead-in period to control for spontaneous recovery (VFSS B), and at the 8-week endpoint of treatment (VFSS C). The study was interrupted due to the COVID-19 pandemic after 1 participant enrollment and is presented as single case study.
Results:
Isometric tongue pressures: Following the 4-week lead-in, a decline in maximum isometric anterior tongue pressure (MAIP) and regular effort saliva swallow pressures (RESS) was noted, however there was no change in maximum posterior isometric tongue pressures (MPIP). Isometric tongue pressures improved post-treatment, with increases in MAIP, MPIP, and to a lesser degree RESS.
Swallowing Function: Impairments in swallowing safety continued between the baseline VFSS A (Penetration-Aspiration Scale score [PAS]=8) and lead-in VFSS B (PAS=5). Swallowing safety improved following the intervention, with PAS scores = 1 at the endpoint VFSS C. Pixel-based measures of swallowing efficiency revealed a reduced frequency of post-swallow total pharyngeal reside following the treatment. Improvements were found in two other swallowing parameters, laryngeal vestibule closure integrity and pharyngeal area at maximum pharyngeal constriction, at the endpoint VFSS.
Conclusion: These pilot data suggest improvements in some swallowing parameters as an outcome of intervention.
DOI: 10.6084/m9.figshare.27157110.v1
title: <b>Lee et al., 2024, </b><b>Reprogramming of flagellin receptor responses with surrogate ligands</b>

description: Schrödinger suites (ver 2021-4) was used as follows: the crystal structure of FLS2ECD (PDB ID:4MNA) was obtained from the PDB database (https://www.rcsb.org) and processed using the default settings on the Protein Preparation pipeline of the software. 5 different receptor grids (&lt;20Å) were generated to encompass every possible binding pocket on the FLS2 structure. SMILE strings of chemicals were processed into 3D structure for docking by LigPrep. The docking was conducted using Glide XP mode, with flexible ligand setting. 10 poses for each chemical isoforms were extracted based on binding energy prediction computed with MM-GBSA. Subsequently, the lateral chains of FLS2 amino acids participating in interaction with the chemicals within a 12 Å window were extracted. All steps were conducted under simulatory pH=5.3. Visualization of the estimated model was performed using PyMOL (ver 2.5.5).
DOI: 10.5285/ce0c8d35-8bbc-4ef5-a7df-188740330c7b
title: Lagerstatten fossil occurrence data for six Triassic marine communities following the Permian-Triassic mass extinction

description: Lagerstatten fossil occurrence data for six Triassic marine communities following the Permian-Triassic mass extinction. Also included are ecological trait data and feeding rules needed to parameterise food web model - PFIM (Paleo Food web Inference Model). See Dunhill et al. 2024, Nat Comms, https://www.nature.com/articles/s41467-024-53000-2) for method info.

The six Triassic marine communities are;
Dienerian, Guiyang, South China 
Early Spathian, Paris, southeastern Idaho, USA
Spathian, Chaohu, Anhui Province, South China 
Anisian, Luoping, Yunnan, China
Ladinian, Xingyi,Guizhou, China
Carnian, Guanling, China
DOI: 10.6084/m9.figshare.21341766.v2
title: Metagenome and 16S rRNA sequences

description: NCD:C6_1,C6_2,C6_3 HFD:CH10_3,CH10_5,CH13_5 HFD-L:HL10_1,HL10_2,HL13_3 HFD-H:HH13_1,HH13_3,HH13_4
DOI: 10.15468/dl.56x8xn
title: Occurrence Download

description: A dataset containing 4860 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Observation, Human Observation, Machine Observation, Living Specimen)"
 ]
 }
 },
 "TaxonKey is Mercurialis annua L."
 ]
}

 The dataset includes 4860 records from 205 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0009661-250426092105405/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.23295218.v1
title: R codes and data to reproduce main analyses on spatial synchrony and related figures in "<b>Stabilizing effects of spatially heterogeneous disturbance via reduced spatial synchrony on a rocky shore community"</b>

description: R codes and data to reproduce analyses and figures
DOI: 10.6084/m9.figshare.24192486.v1
title: Example code for time-normalized plots (MAT-file)

description: Example MAT-code to create time-normalized plots from the MAT-files
DOI: 10.6084/m9.figshare.23710311.v2
title: <b>Assessment of indoor and outdoor </b><b>formaldehyde, total volatile organic compounds (TVOC), and particulate matter (PM2.5, and PM10) levels in Kalasin</b><b>, Thailand</b>

description: The study was conducted in Kalasin Province in order to determine the levels of formaldehyde, TVOCs, PM2.5, and PM10 present in the air both inside and outside at seven different locations. These locations included important roadways, residential neighborhoods, shopping centers, motorcycle repair shops, gas stations, industrial zones, and rural areas. The findings revealed that formaldehyde levels in stores and motorbike maintenance facilities exceed the Thai Air Standard. This is an important discovery that can help improve air quality in these areas.
DOI: 10.6084/m9.figshare.27902247.v1
title: PRISMA Checklist and Flow Diagram for "Systematic literature review: Servant leadership in public sectors"

description: This dataset includes the PRISMA 2020 checklist and flowchart, supporting the systematic review titled "Systematic literature review: Servant leadership in public sectors." These materials are provided to enhance the transparency and reproducibility of the study.
DOI: 10.6084/m9.figshare.10011467.v1
title: Supplementary Material for: Complications after Radiofrequency Ablation for Hepatocellular Carcinoma: A Multicenter Study Involving 9,411 Japanese Patients

description: <b><i>Introduction:</i></b> Radiofrequency ablation (RFA) for hepatocellular carcinoma (HCC) is considered a safe and minimally invasive procedure. We previously reported that the mortality and complication rates for RFA were 0.038% (5/13,283 patients) and 3.54% (579 complications/16,346 procedures), respectively, from 1999 to 2010 (previous period). In this study, we investigated the clinical criteria for RFA and the mortality and complication rates from 2011 to 2015 (recent period). <b><i>Methods:</i></b> Data were collected from 25 centers by using a questionnaire developed by the Chugoku-Shikoku Society for Local Ablation Therapy of HCC. The criteria for RFA, RFA modification, use of image-guidance modalities, mortality, and complications during the previous and recent periods were compared. <b><i>Results:</i></b> We evaluated 11,298 procedures for 9,411 patients, including those that involved new devices (bipolar RFA and internally adjustable electrode system). The criterion of hepatic function for RFA increased from a Child-Pugh score ≤8 during the previous period to ≤9 during the recent period. The criteria regarding the tumor location and other risk factors have been expanded recently because of the increased use of several modifications of the RFA procedure and image-guidance modalities. The mortality rate was 0.064% (6/9,411 patients), and the complication rate was 2.92% (330 complications/11,298 procedures). There was no difference in mortality rates between the 2 periods (<i>p</i> = 0.38), but the complication rates was significantly lower during the recent period (<i>p</i> = 0.038). <b><i>Discussion and Conclusions:</i></b> Our findings confirmed that RFA, including the use of new devices, is a low-risk procedure for HCC, despite the expansion of the criteria for RFA during the recent period.
DOI: 10.6084/m9.figshare.22072160.v2
title: Untitled Item

description: tables
DOI: 10.6084/m9.figshare.14709306.v1
title: a depth-analysis of organelle genome diversity in 1495 rice hybrids reveals hybrid rice breeding strategy

description: The genomic architecture for heterosis in rice hybrid has been well elucidated. Since cultivated rice is a self-pollinating plant or an inbreeding crop, the rice male sterility varieties, which are unable to produce functional pollen grains and are used as female parents to avoid self-pollination, are prerequisite for efficiently generating hybrid rice varieties to produce large quantities of hybrid seeds. However, we know little about maternally inherited cytoplasmic genome variations for rice hybrids. In this study, we analyzed the cytoplasmic genomes of a collection of 1495 elite hybrid rice (O. sativa) varieties, and revealed 5 major types of hybrid cytoplasm which were adopted in different hybrid production strategies. We revealed that the appliance of cytoplasmic male sterility associated gene WA352c, a new type of mitochondrial genome from wild rice (O. rufipogon) population was introduced to cultivated rice (O. sativa) population and broaden the organelle resource pool. We also conducted organelle genome assembling for 5 representative hybrids from 5 groups, and revealed variable sequence structure for hybrids mtDNA (mitochondrial DNA) but conservative for cpDNA (chloroplast DNA). The functional effects for group-specific nucleotide variations were also evaluated. In order to figure out the interaction between nuclear and cytoplasm could hinder the cross between nuclear genomes, we analyzed the nucleus-genetic relationship among female lines containing 5 types of organelle. There were 4 subtypes of WA352c-based CMS (cytoplasmic male sterile) lines, and subtype 4 had ‘communicated’ with EGMS (environment sensitive male sterile) lines. They shared genomic similarities as well as composition patterns of heterotic loci. Our results showed that, hybrid cytoplasmic genome also contained polymorphisms. It could imply strategies for hybrids production and helped us get better understanding of hybrid rice.
DOI: 10.6084/m9.figshare.28749650.v1
title: Activist Climate Narratives Dataset

description: Dataset of climate related articles scraped from activist sources. Each entry contains the original scraped content, a cleaned version of the content, the url from which it was scraped, the title of the article, a full document embedding, and a cluster number. For full details on the data collection and processing procedures, refer to the associated paper.
DOI: 10.6084/m9.figshare.7616198.v1
title: Dislocation rates with combinations of anti-protrusio cages and dual mobility cups in revision cases: are we safe?

description: This retrospective study included all patients in whom a Burch–Schneider cage and a dual mobility cup were implanted in our department between 2007 and 2014 and who had a minimum follow-up period of 24 months. Implantation of the Burch–Schneider cage was indicated in cases of extensive cup base defects and an unstable caudal cup edge. All patients who had to receive a tumor prosthesis or push-through prosthesis due to a defect situation in the shaft area, or who were undergoing surgery due to a malignant disease, were excluded.
DOI: 10.6084/m9.figshare.17009348.v1
title: Whitt 2021 LES paper, Data for plotting ROMS results

description: Data for plotting ROMS results.
DOI: 10.6084/m9.figshare.27569652.v1
title: A Comparison of Machine Learning-based Approaches in Estimating Surface PM2.5 Concentrations focusing on Artificial Neural Networks and High Pollution Events

description: The dataset contains the raw data used in A Comparison of Machine Learning-based Approaches in Estimating Surface PM2.5 Concentrations focusing on Artificial Neural Networks and High Pollution Events, which was submitted to <i>Atmosphere</i>.
DOI: 10.6084/m9.figshare.12546563.v1
title: Virus survival in evaporated saliva microdroplets deposited on inanimate surfaces

description: Raw data of Virus survival via plaque assays. This Dataset was used to prepare Fig. 4 in the Paper.<br>