cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.5718952.v1
title: Regional health network in the Amazonian context: the case in Manaus, Entorno and Alto Rio Negro

description: Abstract Objectives: to analyze the dimensions of policy, structure and organization in the construction of Redes de Atenção à Saúde (RAS) (healthcare networks) in the health region of Manaus, Entorno and Alto Rio Negro, focusing on Atenção Primária à Saúde (APS) (primary healthcare) and Rede de Urgência e Emergência (RUE) (urgency and emergency network). Methods: a case study with multidimensional analysis using quantitative and qualitative approach carried out in the first semester of 2016. Results: 37 interviewed key informants, such as managers (States, Cities and Regionals), providers and civil society. The reality was marked by the difficulties in the implementation of RAS's with centralized decision-making powers of State level. Perception of insufficient human resources of limited installed capacity, particularly in the APS, with insufficient priority given to this level of care. Concentration of services in Manaus, priority for urgency and emergency actions expressed in the greatest investment in human resources and mate-rials allocated at this level of care, lack of proposals for promoting equity. Conclusions: the Region was unable to implement RAS to respond to the health demands in the region. The necessity to overcome the dependency relation with the cities and the State and to strengthen its protagonism and fulfillits roles in management network, instituting a plan capable of strengthening APS to be committed in reducing iniquities and with adequate responses in health needs.
DOI: 10.6084/m9.figshare.5718949.v1
title: Nurse training in health in different regions in Brazil

description: Abstract Objectives: to identify on the one hand whether there has been any changes in the nurse training in Brazil and on the other if regionalizing health incurred interference in this process. Methods: an exploratory research of a multiple case study in a qualitative approach developed between November 2015 and March 2017, in seven regions in Brazil. The data were collected by in-depth interviews with 16 administrators of the undergraduate courses in nursing and by documentary analysis of the Projetos Políticos Pedagógicos (Political Pedagogical Projects). Content analysis was undertaken by having the theoretical references of the Diretrizes Curriculares Nacionais (National Curriculum Guidelines). Results: varied profiles of undergraduates were observed with higher tendency for the basic level in health practice or for hospital level with competencies in health care that is still fragmented and not interdisciplinary. The curricular structure of the courses focuses on isolated disciplines with little or no interdisciplinary integration and the pedagogical model is based on traditional teaching-learning strategies and additional evaluation process. There were no differences in health among the regions. Conclusions: it is necessary in concomitance with the changes that are required in the field of training to undertake efforts in the development of health units and training institutions, which has already proven to be a factor of professional retention and regional development.
DOI: 10.6084/m9.figshare.5718946
title: Trend of Observed and Projected Extreme Climate Indices in Minas Gerais State

description: Abstract Climate extreme indices of temperature and precipitation over Minas Gerais are analyzed by using 19 General Circulation Models belonging to the CMIP5 in 1948-2005 period and during the periods of 2041-2070 and 2071-2100. The Reanalysis (NCEP / NCAR) data is also used for the 1948-2005 period for comparison with simulations models, as well as, conventional meteorological station data for the 1961-2014 period. Trend analysis of these indices is made through the statistical Mann-Kendall and Sen’s Slope estimator for spatial means of the indexes in two study areas: north and south of Minas Gerais (NMG and SMG, respectively). Generally, the temperature-related indices have higher tendencies of values than the precipitation rates, are significant in most and show an increase of hot days and nights and a reduction of cold days and nights in Minas Gerais. Regarding to precipitation, even with few significant amounts, one can observe an increase in dry conditions in the NMG region and humid conditions in the SMG, intensifying the existing differences in the state. Therefore, these results may have important implications for studies of climatic extremes and monitoring activities of the extreme features of temperature and rainfall in Minas Gerais.
DOI: 10.6084/m9.figshare.5718946.v1
title: Trend of Observed and Projected Extreme Climate Indices in Minas Gerais State

description: Abstract Climate extreme indices of temperature and precipitation over Minas Gerais are analyzed by using 19 General Circulation Models belonging to the CMIP5 in 1948-2005 period and during the periods of 2041-2070 and 2071-2100. The Reanalysis (NCEP / NCAR) data is also used for the 1948-2005 period for comparison with simulations models, as well as, conventional meteorological station data for the 1961-2014 period. Trend analysis of these indices is made through the statistical Mann-Kendall and Sen’s Slope estimator for spatial means of the indexes in two study areas: north and south of Minas Gerais (NMG and SMG, respectively). Generally, the temperature-related indices have higher tendencies of values than the precipitation rates, are significant in most and show an increase of hot days and nights and a reduction of cold days and nights in Minas Gerais. Regarding to precipitation, even with few significant amounts, one can observe an increase in dry conditions in the NMG region and humid conditions in the SMG, intensifying the existing differences in the state. Therefore, these results may have important implications for studies of climatic extremes and monitoring activities of the extreme features of temperature and rainfall in Minas Gerais.
DOI: 10.6084/m9.figshare.5718943
title: Genetic variability during four cycles of recurrent selection in rice

description: Abstract: The objective of this work was to estimate genetic and phenotypic parameters among progenies of the CNA6 population of upland rice (Oryza sativa) for grain yield and plant height in four cycles of recurrent selection, in order to evaluate the genetic variability and the genotype × location interaction. The experimental data were obtained from yield trials of S0:2 progenies, which were carried out in the experimental design of Federer’s augmented blocks, without replications for progenies within each location. The effect of S0:2 progenies was significant in all cycles for grain yield and in the first three cycles for plant height, indicating the maintenance of the population’s genetic potential to generate transgressive progenies. The participation of the component of the progeny × location interaction in phenotypic variance was of high magnitude. The genetic variability of the CNA6 population of upland rice is maintained for grain yield and plant height during the four cycles of recurrent selection.
DOI: 10.6084/m9.figshare.5718943.v1
title: Genetic variability during four cycles of recurrent selection in rice

description: Abstract: The objective of this work was to estimate genetic and phenotypic parameters among progenies of the CNA6 population of upland rice (Oryza sativa) for grain yield and plant height in four cycles of recurrent selection, in order to evaluate the genetic variability and the genotype × location interaction. The experimental data were obtained from yield trials of S0:2 progenies, which were carried out in the experimental design of Federer’s augmented blocks, without replications for progenies within each location. The effect of S0:2 progenies was significant in all cycles for grain yield and in the first three cycles for plant height, indicating the maintenance of the population’s genetic potential to generate transgressive progenies. The participation of the component of the progeny × location interaction in phenotypic variance was of high magnitude. The genetic variability of the CNA6 population of upland rice is maintained for grain yield and plant height during the four cycles of recurrent selection.
DOI: 10.6084/m9.figshare.5718940
title: Healthier Sairé: a intersectorial policy as a turning point for local equity

description: Abstract Public health studies see intersectoriality as a strategy to promote equity in addressing the social determinants of health. The municipality of Sairé, a member of the Healthy Pernambuco Municipalities Network (RPMS), stands out for its adoption of an intersectorial policy, named A Healthier Sairé. This present study examines how this policy has promoted local equity. It was a case study using a timeline to record critical events, analysis of documents, interviews and participant observation. Actor-Network Theory (ANT) was used as a theoretical reference, and showed how adoption of the municipal policy had been central in promoting local empowerment and equity. The results, based on the timeline, demonstrate that initially it was necessary to obtain a cognitive translation, conducted through the direct influence and responsibility of the RPMS, which facilitated a second, strategic translation, with the construction of a policy anchored on the municipal program - which is currently being translated logistically into concrete actions directed towards equity. Key factors in this process for promoting local equity were: the role of strategic leadership; the value given to training; and the retention and use of structures that had previously been built.
DOI: 10.6084/m9.figshare.5718937
title: Mentha pulegium crude extracts induce thiol oxidation and potentiate hemolysis when associated to t-butyl hydroperoxide in human’s erythrocytes

description: ABSTRACT Mentha pulegium (Lamiaceae) tea has been used as a traditional medicine; however, the modulatory effect of M. pulegium extracts on damage to human erythrocytes associated to t-butyl hydroperoxide (t-BHP) exposure remains to be investigated. Accordingly, we perform this study in order to test the hypothesis that aqueous and ethanolic extracts of M. pulegium could modulate the hemolysis associated to t-BHP exposure, non-protein thiol (NPSH) oxidation and lipid peroxidation (measured as thiobarbituric acid reactive substances - TBARS) in human erythrocytes. Samples were co-incubated with t-BHP (4 mmol/L) and/or aqueous or ethanolic extracts (10-1000 mg/mL) during 120 min to further analysis. We found that both extracts, when associated to t-BHP, potentiate NPSH oxidation and hemolysis. Moreover, both extracts significantly prevents against t-BHP-induced TBARS production. A significant correlation among hemolysis and NPSH levels was found. Taking together, our data points that the association of M. pulegium extracts with t-BHP culminates in toxic effect to exposed erythrocytes, besides its protective effect against t-BHP-induced TBARS production. So, we infer that the use of this extract may exert negative effect during painful crisis in sickle cell anemia. However, more studies are still necessary to better investigate/understand the mechanism(s) involved in the toxic effect resultant from this association.
DOI: 10.6084/m9.figshare.5718937.v1
title: Mentha pulegium crude extracts induce thiol oxidation and potentiate hemolysis when associated to t-butyl hydroperoxide in human’s erythrocytes

description: ABSTRACT Mentha pulegium (Lamiaceae) tea has been used as a traditional medicine; however, the modulatory effect of M. pulegium extracts on damage to human erythrocytes associated to t-butyl hydroperoxide (t-BHP) exposure remains to be investigated. Accordingly, we perform this study in order to test the hypothesis that aqueous and ethanolic extracts of M. pulegium could modulate the hemolysis associated to t-BHP exposure, non-protein thiol (NPSH) oxidation and lipid peroxidation (measured as thiobarbituric acid reactive substances - TBARS) in human erythrocytes. Samples were co-incubated with t-BHP (4 mmol/L) and/or aqueous or ethanolic extracts (10-1000 mg/mL) during 120 min to further analysis. We found that both extracts, when associated to t-BHP, potentiate NPSH oxidation and hemolysis. Moreover, both extracts significantly prevents against t-BHP-induced TBARS production. A significant correlation among hemolysis and NPSH levels was found. Taking together, our data points that the association of M. pulegium extracts with t-BHP culminates in toxic effect to exposed erythrocytes, besides its protective effect against t-BHP-induced TBARS production. So, we infer that the use of this extract may exert negative effect during painful crisis in sickle cell anemia. However, more studies are still necessary to better investigate/understand the mechanism(s) involved in the toxic effect resultant from this association.
DOI: 10.6084/m9.figshare.5718934
title: Chronic Periodontitis and RANKL/OPG Ratio in Peri-Implant Mucosae Inflammation

description: Abstract tHistory of chronic periodontitis (CP) is a risk factor for oseointegration failure. The osteoclastogenesis system (RANK, RANKL and OPG) is critical for bone homeostatic control. We investigated the levels of OPG and RANKL in peri-implant tissues from volunteers with and without a history of CP and their association with mucosae inflammation. This is a single-blind case-contro study. Diagnosis of a history of CP and peri-implant examination was performed on 46 volunteers, divided into control (without history of CP, n=26) and CP group (with history of CP, n=20). Gingival biopsies were harvested during implant exposure. Quantitative PCR evaluated OPG/RANKL mRNA expressions. OPG and RANKL proteins were analyzed by western blot and immunohistochemistry assay. The chi-square test analyzed the significance of nominal variables between groups while continuous variables were analyzed by T-test or Mann-Whitney test, after Shapiro-Wilk test evaluation. The 2-ΔΔCT Livak method calculation evaluated the gene expression. Values of p&lt;0.05 were considered statistically significant. Volunteers with CP history had 23 times higher chance of developing mucosae inflammation. High mucosae levels of RANKL (p=0.04) and RANKL/OPG (p=0.001) mRNA expressions were observed in CP group. CP volunteers showed increased RANKL protein levels in opposition to decreased OPG expression. Even without active periodontitis, volunteers with a history of CP had elevated gingival levels of RANKL/OPG and higher correlation with peri-implant mucosae inflammation and implant loss.
DOI: 10.6084/m9.figshare.5718934.v1
title: Chronic Periodontitis and RANKL/OPG Ratio in Peri-Implant Mucosae Inflammation

description: Abstract tHistory of chronic periodontitis (CP) is a risk factor for oseointegration failure. The osteoclastogenesis system (RANK, RANKL and OPG) is critical for bone homeostatic control. We investigated the levels of OPG and RANKL in peri-implant tissues from volunteers with and without a history of CP and their association with mucosae inflammation. This is a single-blind case-contro study. Diagnosis of a history of CP and peri-implant examination was performed on 46 volunteers, divided into control (without history of CP, n=26) and CP group (with history of CP, n=20). Gingival biopsies were harvested during implant exposure. Quantitative PCR evaluated OPG/RANKL mRNA expressions. OPG and RANKL proteins were analyzed by western blot and immunohistochemistry assay. The chi-square test analyzed the significance of nominal variables between groups while continuous variables were analyzed by T-test or Mann-Whitney test, after Shapiro-Wilk test evaluation. The 2-ΔΔCT Livak method calculation evaluated the gene expression. Values of p&lt;0.05 were considered statistically significant. Volunteers with CP history had 23 times higher chance of developing mucosae inflammation. High mucosae levels of RANKL (p=0.04) and RANKL/OPG (p=0.001) mRNA expressions were observed in CP group. CP volunteers showed increased RANKL protein levels in opposition to decreased OPG expression. Even without active periodontitis, volunteers with a history of CP had elevated gingival levels of RANKL/OPG and higher correlation with peri-implant mucosae inflammation and implant loss.
DOI: 10.6084/m9.figshare.5718928
title: Reflections on teachers' educations in a science center: trajectory, conceptions and formative practices

description: Abstract: In the present article we describe the trajectory, formative practices and pedagogical models most frequently employed in teachers' continuing education experiences at the Sciences Center of the Federal University of Juiz de Fora between 2007 and 2015. As data sources, we have used reports made to financial support agencies, research that was conducted with the mentioned courses as an object of study and notes and observations from mediators. As theoretical support for the analysis we have used the formation models: (i) classical; (ii) reflexive practical; and (iii) political-emancipatory. We emphasize that these models are an important reference for the analysis and reflection on the training practices that we have been developing offering support to promote changes in the design of continuing education projects and the trajectory of the same, moving from the classical training model towards the emancipatory-political model. This discussion is of great relevance to the current debate on teacher education.
DOI: 10.6084/m9.figshare.5718928.v1
title: Reflections on teachers' educations in a science center: trajectory, conceptions and formative practices

description: Abstract: In the present article we describe the trajectory, formative practices and pedagogical models most frequently employed in teachers' continuing education experiences at the Sciences Center of the Federal University of Juiz de Fora between 2007 and 2015. As data sources, we have used reports made to financial support agencies, research that was conducted with the mentioned courses as an object of study and notes and observations from mediators. As theoretical support for the analysis we have used the formation models: (i) classical; (ii) reflexive practical; and (iii) political-emancipatory. We emphasize that these models are an important reference for the analysis and reflection on the training practices that we have been developing offering support to promote changes in the design of continuing education projects and the trajectory of the same, moving from the classical training model towards the emancipatory-political model. This discussion is of great relevance to the current debate on teacher education.
DOI: 10.6084/m9.figshare.5718925
title: Evaluation of forage grass resistance to Mahanarva fimbriolata (Stål)

description: ABSTRACT The aim of this study was to select forage grasses with potential resistance to Mahanarva fimbriolata by assessing effects on insect. No-choice assays were conducted with 12 genotypes and laboratory-reared insects. The following parameters were assessed: mortality and duration of the nymphal stage; adult weight and longevity; pre-oviposition period; number of eggs/female; viability and duration of the embryonic period. As main result it was verified that the mortality of nymphs reared on Panicum maximum cv. Paredão is almost complete and that this forage grass may be characterized as resistant to this insect by antibiosis. Further, the grasses can be divided into three groups following a cluster analysis: P. maximum cv. Aries, Setaria sphacelata cv. Kazungula, Brachiaria humidicola, A. gayanus and P. maximum cv. Aruana, which are insect-resistant grasses; Brachiaria decumbens cv. Basilisk, B. dictyoneura, B. brizantha cv. MG-4 and B. ruziziensis, which are moderately resistant grasses; and B. brizantha MG-5 and B. brizantha ecotype BB185, which are susceptible grasses.
DOI: 10.6084/m9.figshare.5718925.v1
title: Evaluation of forage grass resistance to Mahanarva fimbriolata (Stål)

description: ABSTRACT The aim of this study was to select forage grasses with potential resistance to Mahanarva fimbriolata by assessing effects on insect. No-choice assays were conducted with 12 genotypes and laboratory-reared insects. The following parameters were assessed: mortality and duration of the nymphal stage; adult weight and longevity; pre-oviposition period; number of eggs/female; viability and duration of the embryonic period. As main result it was verified that the mortality of nymphs reared on Panicum maximum cv. Paredão is almost complete and that this forage grass may be characterized as resistant to this insect by antibiosis. Further, the grasses can be divided into three groups following a cluster analysis: P. maximum cv. Aries, Setaria sphacelata cv. Kazungula, Brachiaria humidicola, A. gayanus and P. maximum cv. Aruana, which are insect-resistant grasses; Brachiaria decumbens cv. Basilisk, B. dictyoneura, B. brizantha cv. MG-4 and B. ruziziensis, which are moderately resistant grasses; and B. brizantha MG-5 and B. brizantha ecotype BB185, which are susceptible grasses.
DOI: 10.6084/m9.figshare.5718916
title: Use of a child health surveillance instrument focusing on growth. A cross-sectional study

description: ABSTRACT BACKGROUND: Proper use of a child health handbook is an important indicator of the quality of care provided to children at healthcare services. This study aimed to evaluate the use of child health surveillance tool (by health professionals?), especially focusing on growth. DESIGN AND SETTING: Cross-sectional study carried out in the context of the Family Health Strategy in two municipalities in Paraíba, Brazil. METHODS: Three hundred and twenty-one children under five years of age from areas covered by health workers were included in the study. Mothers answered a questionnaire asking for information on sociodemographic characteristics. Growth charts, records of iron and vitamin A supplementation and notes on immunization schedules registered in the instrument were analyzed. In the case of children for whom the third version of the child health handbook was used, the association between completion of this handbook and sociodemographic characteristics was analyzed. RESULTS: All the parameters studied showed high frequencies of inadequate data entry, ranging from 41.1% for the weight-versus- age chart to 95.3% for the body mass index-versus-age chart. Higher frequency of inadequate data entry was found among children aged 25 months and over and among those living in areas of these municipalities with minimal numbers of professionals in the healthcare teams. CONCLUSIONS: The use of a child health handbook to monitor children’s growth in the municipalities studied appeared to be faulty. Data entry to this instrument was better at locations with larger healthcare teams.