cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.24631071.v1
title: Supplementary Material for: European Nephrologists' Attitudes Towards the Application of Artificial Intelligence in Clinical Practice: A Comprehensive Survey

description: Introduction: The rapid advancement of artificial intelligence and big data analytics, including descriptive, diagnostic, predictive, and prescriptive analytics, has the potential to revolutionize many areas of medicine, including nephrology and dialysis. Artificial intelligence and big data analytics can be used to analyse large amounts of patient medical records, including laboratory results and imaging studies, to improve the accuracy of diagnosis, enhance early detection, identify patterns and trends, and personalize treatment plans for patients with kidney disease. Additionally, artificial intelligence and big data analytics can be used to identify patients’ treatment who are not receiving adequate care, highlighting care inefficiencies in the dialysis provider, optimizing patient outcomes, and reducing healthcare costs, and consequently creating values for all the involved stakeholders. 
Objectives: We present the results of a comprehensive survey aimed at exploring the attitudes of European physicians from eight countries working within a major hemodialysis network (Fresenius Medical Care) towards the application of Artificial intelligence in clinical practice. 
Methods: An electronic survey on the implementation of artificial intelligence in hemodialysis clinics was distributed to 1,067 physicians. Of the 1,067 individuals invited to participate in the study, 404 (37.9%) professionals agreed to participate in the survey. Results: The survey showed that a substantial proportion of respondents believe that artificial intelligence has the potential to support physicians in reducing medical malpractice or mistakes. 
Conclusion: While artificial intelligence's potential benefits are recognized in reducing medical errors and improving decision-making, concerns about treatment plan consistency, personalization, privacy, and the human aspects of patient care persist. Addressing these concerns will be crucial for successfully integrating artificial intelligence solutions in nephrology practice.
DOI: 10.6084/m9.figshare.28868627.v1
title: <i>Escherichia coli </i>bacteriophage<i> </i>MLS11<i> </i>complete genome

description: The phage is an <i>Escherichia coli</i> bacteriophage that can lyse the atypical Enteropathogenic <i>E. coli</i> (aEPEC), which was isolated and purified by the animal bacterial disease epidemiology research and comprehensive prevention and control innovation team of Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences.
DOI: 10.6084/m9.figshare.12866801.v1
title: Supplementary Material for: Identification of Seasonal Variations of Antibodies against PR-10-Specific Epitopes Can Be Improved Using Peptide-Phage Display

description: <b><i>Background:</i></b> In pollinosis patients, allergen-specific antibody titers show seasonal variations. Little is known about these variations at the epitope level. <b><i>Objectives:</i></b> We aimed at investigating seasonal variations on the level of allergen epitope recognition in patients with Bet v 1-related food allergy using a peptide phage display approach. <b><i>Methods:</i></b> Serum samples collected over 1 year from 4 patients of the placebo arm of the birch-associated soya allergy immunotherapy trial were included. To identify epitopes from Bet v 1-related food allergens, patient sera were used in peptide phage display experiments. In silico analysis of enriched allergen-related motifs was performed. <b><i>Results:</i></b> We identified epitope motifs related to Bet v 1 and its homologs in soya and hazelnut (Gly m 4 and Cor a 1, respectively) that were enriched in accordance with birch and hazel pollen exposure. Within several weeks after the birch pollen season peak, the pattern of identified epitope motifs differed considerably among patients. Data for amino acid preferences in homologous Bet v 1 and Cor a 1 epitope motifs identified for one of the investigated patients suggest changes in concentration or specificity of serum antibodies for the Cor a 1 epitope motif. <b><i>Conclusions:</i></b> Peptide phage display data suggest an impact of birch and hazel pollen exposure on the recognition pattern of Bet v 1-like allergen epitopes. Epitope-oriented analyses could provide deeper, personalized details regarding the allergen epitope recognition influenced by pollen exposure beyond the capability of current methods.
DOI: 10.6084/m9.figshare.24131789.v1
title: Structural insight into G2019S mutated LRRK2 kinase and brain-penetrant type I inhibitor complex: a molecular dynamics approach

description: More than 40 mutations in the multidomain leucine-rich repeat kinase 2 (LRRK2) are found and mutation G2019S in the kinase domain is the most concerned with Parkinson’s disease (PD). The discovery of the various types of inhibitors has largely emerged recently. However, the comparative study on molecular insight in WT and G2019S LRRK2 kinase domain upon binding of the inhibitors has not yet been explored in detail. This work considered five ATP-competitive Type I inhibitors complexed with WT and mutated LRRK2 kinase. Three reported potent and brain-penetrant inhibitors, GNE-7915, PF-06447475 and MLi-2 (comp1, comp2 and comp3 respectively) and also, another two inhibitors, Pyrrolo[2,3-b] pyridine derivative (comp4) and Pyrrolo[2,3-d] pyrimidine derivative (comp5), were used. In this work, classical and accelerated molecular dynamics (cMD and aMD) simulations were performed for a total of 12 systems (apo and holo). This study found structural and thermodynamic stability for all the inhibitors. Comparatively larger molecules (size 15.3 − 15.4 Å), comp1, comp3 and comp5, showed more selectivity towards mutated LRRK2 kinase in terms of flexibility of residues, compactness and dynamics of kinase, the stability inside the binding-pocket. Also, inhibitors comp3 and comp5 showed higher binding affinity towards G2019S LRRK2 among the five. Residues, E1948 and A1950 (in hinge region) were observed mainly to form hydrogen bonds with inhibitors. Finally, MLi-2 showed a conformational rearrangement by dihedral flipping in both WT and mutated systems but got stability in G2019S LRRK2. This work could potentially help design more improved and effective Type I inhibitors for G2019S LRRK2 kinase. Among five Type-I inhibitor molecules, comp1 (GNE-7915), comp2 (PF-06447475), comp3 (MLi-2), comp4 (Pyrrolo[2,3-b]pyridine derivative), comp5 (Pyrrolo[2,3-d]pyrimidine derivative), comparatively larger molecules (comp1, comp3 and comp5) showed selectivity towards G2019S LRRK2 and a stable conformation for MLi-2 (after dihedral flipping of the molecule) was found in the mutated system. Communicated by Ramaswamy H. Sarma
DOI: 10.17632/d6dwfvpz5x
title: Aswan DEM

description: SRTM for Aswan area in EGYPT
DOI: 10.6084/m9.figshare.12611819.v1
title: Source Data

description: Source Data of <i>in vivo</i> experiment in the main figures.
DOI: 10.6084/m9.figshare.25196051.v1
title: Supplementary Material for: Early Brain Activity in Very Preterm Infants of Mothers with Gestational Diabetes Mellitus: A Pilot Study

description: <b><i>Introduction:</i></b> Neurological consequences of preterm infants born to mothers with gestational diabetes mellitus (GDM) are unclear. In this pilot study, we investigated the effect of GDM on brain activity in very preterm infants. <b><i>Methods:</i></b> Preterm infants &lt;32 gestational weeks of mothers with GDM compared to gestational age- and sex-matched controls born between 2011 and 2018 were included. Amplitude-integrated electroencephalography (aEEG) was assessed for total maturation and individual component scores according to Burdjalov and colleagues, the dominating visual background, and the presence of sleep-wake cycles per hour in the first 72 h of life and weekly at days 7, 14, 21, and 28. <b><i>Results:</i></b> We included 47 infants of mothers with GDM and 94 control infants. Both the aEEG total maturation score and its individual component scores, as well as the percentage of continuous background pattern, increased equally during the first 4 weeks after birth in both groups. GDM-exposed infants showed a slightly but significantly higher number of sleep-wake cycles per hour. <b><i>Conclusion:</i></b> We found normal maturation of brain activity in the first 4 weeks after birth in very preterm infants born to mothers with GDM, not differing from a very preterm control group. The higher number of sleep-wake cycles per hour in GDM-exposed infants could indicate transiently enhanced maturation. Further studies on brain activity and brain development in very preterm infants of mothers with GDM are needed to validate our results.
DOI: 10.6084/m9.figshare.28333532.v1
title: THE ROLE OF SANDY ENVIRONMENT IN ENHANCING GROWTH, COGNITION AND REPRODUCTION IN CULTURED SENEGALESE SOLE FEMALES

description: These datasets are associated with the study performed in Senegalese sole females, where animals were monitored for 2 years in different conditions using sand as environmental enrichment to observe differences between groups at several physiological and genomic levels.
DOI: 10.17632/rjytc5c3cr
title: Data associated with PEARL-catalyzed peptide bond formation after chain reversal by ureido-forming condensation domains. ACS Cent Sci 2024

description: Data associated with Yu et al ACS Cent Sci 2024 doi:10.1021/acscentsci.4c00044
DOI: 10.6084/m9.figshare.22044047.v1
title: Effect of anti-retroviral regimen on proximal tubular function in Zambian adolescents and young adults living with HIV

description: We conducted a cross-sectional study involving 180 adolescents and young adults receiving antiretroviral theray for at least 12 months at the University Teaching Hospitals (UTHs) in Lusaka, Zambia. These were either on Tenofovir or Abacavir-based antiretroviral regimen . SmartCare, a national HIV electronic medical database, was used to select eligible participants between May 2018 and March 2019 using a checklist to verify eligibility. All participants were aged between 10 and 24 years who had received ART for a minimum of 12 months and had a documented normal estimated glomerular filtration rate (eGFR) at initiation of the current antiretroviral regimen. Written informed consent and/or assent for participation in this study were obtained from each participant and/or parent or guardian. The study adhered to the declaration of Helsinki <strong>Data collection</strong> Individual participant data were collected from Smart Care, interviews, and physical examination including current age, sex, current weight, body mass index (BMI), current ART regimen and duration, baseline CD4+ cell count, self-reported 85% ART adherence, previous or current tuberculosis, and baseline creatinine or estimated Glomerular Filtration Rate (eGFR). Participants were requested to provide two first-morning spot urine specimens for urinary protein and creatinine levels to calculate a mean (2-sample) urine protein to creatinine ratio (UPCR). The second first-morning urine was obtained within 7-14 days of the first specimen. Each spot urine sample was analyzed for markers of tubular function, urinary b2-microglobulin, a1-microglobulin, creatinine, and urine phosphate. Urine β2-microglobulin and α1-microglobulin were determined by Enzyme-linked immunosorbent assays (ELISA) with detection range of 31.25—2000 ng/mL and 4.69-300 ng/mL. All reagents, samples and standards were prepared according to the instructions in the manufacturer’s manual (Wuhan Elabscience Biotechnology Co. Ltd, Donghu Hi-Tech Development Area, Wuhan, Hubei, China). The urinary proteins were expressed as the ratio-to-creatinine (a1-MCR, b2-MCR, and UPCR) to adjust for variations in urine concentration. Serum or plasma samples were analyzed for CD4+ cell count, HIV viral load, hemoglobin, calcium, potassium, uric acid, urea, phosphate, serum creatinine, and albumin.
DOI: 10.6084/m9.figshare.12733121.v1
title: A Novel Small-Molecule Inhibitor of Endosomal TLRs Reduces Inflammation and Alleviates Autoimmune Disease Symptoms in Murine Models.

description: Supplementary data from our published article A Novel Small-Molecule Inhibitor of Endosomal TLRs Reduces Inflammation and Alleviates Autoimmune Disease Symptoms in Murine Models. You can see the co-authors in the publication. The data were collected from the cited reference publications.<br>
DOI: 10.17632/f2kx4ch76r
title: dataset of urban freight transport survey

description: This file presents raw inferential statistical data that determined the impact of accessibility, congestion, safety, and ecological impacts on the performance of urban freight transport. A survey was carried out among the freight transport managers and users in the city of Fez.
DOI: 10.17632/f76vgddrms
title: Data for "Sources and behaviors of 210Pb and 137Cs in the Yellow Sea sediment: Sedimentation rates and deposition fluxes"

description: Activities and deposition fluxes of Pb-210 and Cs-137 in the Yellow Sea sediments; The Yellow Sea sedimentation rates
DOI: 10.25451/flinders.27139428.v1
title: ESOC 2024 - Modernising Mirror Therapy - Beltrame - Poster

description: Poster presented at the European Stroke Organisation Conference (ESOC) 2024 by Beltrame et al. for the research titled "<i>Modernising</i><i> Mirror Therapy: </i><i>Adding Music & Virtual Reality to Improve Engagement</i><i>".</i>
DOI: 10.6084/m9.figshare.27110083.v1
title: <b>Post-collapse somatic growth and population recovery failure of sardine (</b><b><i>Sardinops sagax</i></b><b>) in the northern Benguela from otolith biochronologies</b>

description: The sardine (<i>Sardinops sagax</i>) stock was majorly exploited in the past (1950-1999) in Namibia with catches totalling 14.7 million tons which led to sardine’s collapse and it’s yet to recover. We developed a robust otolith biochronology of annual increment width to infer long-term growth patterns of sardine using 744 otoliths archived in Namibia from 1982 to 2021. All archived otoliths used were sourced from the Ministry of Fisheries and Marine Resources (MFMR) in Namibia. The archived otoliths stems from MFMR annual purse-seine surveys as well as commercial port samples. The annual hydro-acoustic pelagic biomass survey covers the entire shelf area, starting from north of Lüderitz town ending south of Angola. Commercial port otolith samples were taken from port of Walvis Bay sampled from commercial purse-seine vessels. Thus, events are titled according to the biomass survey or the commercial port samples.<br>Biological measurement obtained from archived otolith (if available) were recorded such as total lengths (TL ± 0.01 mm), month, year and station number. The sagittal otoliths were mounted whole in black Perspex plate moulds and embedded in epoxy resin. Calibrated images of the sardine otoliths were taken using Zeiss Stemi 508 stereo microscope that is fitted with a Carl Zeiss Axiocam 208 colour camera. In order to assess the age of sardine at a given length, otolith annual growth increments were counted (core to edge) along the otolith's largest radius using a Zeiss Stemi 508 stereo microscope 320× magnification. We analysed a total of 787 otolith images using ObjectJ which is an ImageJ plugin (http://imagej.nih.gov/ij/). The length of each annual increment on the along the post-rostrum axis of the otolith from the nucleus to posterior edge.<br>Linear mixed effect models were applied to separate intrinsic (within individual) and extrinsic (by year – e.g. population density, environment) factors to estimate mean annual growth for fish older than 1 year (&gt;1 years). The increment widths were recorded together with its year when the increment was formed (calendar year), and age at the time of increment formation (Age) for each fish.<br>Project(s): TRIATLAS (Tropical and South Atlantic Climate-based Marine Ecosystem Prediction for Sustainable Management)<br>Funding: Horizon 2020. Grant award no. AMD-817578-41: TRIATLAS Project<br>
DOI: 10.6084/m9.figshare.6958910.v1
title: soil pH values

description: soil pH
DOI: 10.6084/m9.figshare.1597662.v1
title: Social Influences in Sequential Decision Making_Raw_Data

description: Raw Data from PlosOne Paper: <br>Social Influences in Sequential Decision Making<br>
DOI: 10.6084/m9.figshare.21590673.v2
title: Data & Code for: Adaptive phenotypic and genomic divergence in the common chaffinch <em>Fringilla coelebs</em> following niche expansion within a small oceanic island Published in Journal of Evolutionary Biology

description: The data includes separated by folder the datasets and scripts to perform different analysis, including: <br> 1.VCFs 2. Morphology 3. Colour 4. RDA 5. BayPass 6. TopGo <br> Each folder contains a README.txt that explains each file.
DOI: 10.6084/m9.figshare.5669008.v1
title: Determination of the pi (π) number through square net of identical resistors

description: The number π is generally described as the value obtained from the perimeter per diameter ratio of a circumference. But this number appears in various circumstances in the sciences in general, especially when a system has periodicity. In this work we present a way to obtain this mathematical constant experimentally by measuring the equivalent resistance in an resistors infinite square grid. Measurements were made throughout the fabrication process using real resistors and simulating them in an online application. The measurements show that the greater the number of layers of the mesh, the closer the value of π is reached. We will also present other alternative ways of performing such an experiment.
DOI: 10.6084/m9.figshare.6989024.v2
title: fMRI results

description: Relevent fMRI images for: <br>B. McCoy, S. Jahfari, G. Engels, T. Knapen, J. Theeuwes (2018). Dopaminergic medication reduces striatal sensitivity to negative outcomes in Parkinson's disease.
DOI: 10.17632/f2yfz4r9fr
title: Medical Sentiment Analysis Dataset for Kurdish Short Text over Social Media

description: Data Description

The Kurdish language is one of the languages of the Middle East that is used for speaking by Kurdish people. Central Kurdish (Sorani) and Kurmanji are two popular dialects of the Kurdish Language [1, 2]. In this project, the Sorani dialect is used for collecting the database. The texts of Sorani Kurdish are like Persian, Arabic, and Urdu that are written from right to left. The characters among those languages are almost like each other but sometimes have different Unicode as shown in Table 1. The number of Sorani Kurdish alphabets is 36 that is divided into vowels (ا, ه‌, و, ۆ, وو, ى, ێ) and consonants (ئ, ب, پ, ت, ج, چ, ح, خ, د, ر, ڕ, ز, ژ, س, ش, ع, غ, ف, ڤ, ق, ک گ, ل, ڵ, م, ن, ه, (و, ى)) [3, 4]. The character (و, ى)  used as vowels and constants based on the positions of the word for example the word (گوڵ) (gull) means (Flower) the (و)  is vowel while the word (وازى) (wazi) means (game) the (و) is constant and the word (يارى) (yari) means (play) the first  (ى) is constant by contrast the second one is a vowel. The Kurdish language is complex and has different scripts (no standard) for Sorani dialect for example in some sources (ك) is used instead of (ک) [3, 4].

Dataset Labeling:

After collecting the dataset, another important step is labeling the samples. For this purpose, three annotators read the samples accurately and manually labeled the unlabeled samples for two classes (medical and non-medical). This process needs a huge effort and consumes time. For labeling each sample, the annotator annotates the sample based on some special words in the medical domain and the meaning of each sentence as shown in Table 4:
DOI: 10.6084/m9.figshare.28817420.v1
title: GFP mRNA transfection in Primary Human T cells

description: Flow cytometry data for GFP mRNA transfection in Primary Human T cells transfected with electroporation parameters 500V, 2 ms, 2 pulses or 0V, 2 ms, 2 pulses and with and without the presence of GFP mRNA.
DOI: 10.6084/m9.figshare.28882952.v2
title: Supplementary Materials- Factors Influencing Individual’s Privacy-Protective Behavior in the Age of Surveillance Capitalism

description: Measurement Items
DOI: 10.6084/m9.figshare.3549870.v1
title: Appendix A. Spatial distribution of research sites and burn plots.

description: Spatial distribution of research sites and burn plots.
DOI: 10.6084/m9.figshare.14563500.v1
title: Sahle Largest net

description: Largest connected component of the sahle network of metal binding spheres
DOI: 10.6084/m9.figshare.12901682.v1
title: HRV_Data_Antarctic Station Neymayer III.txt

description: Heart rate and heart rate variability indices in frequency domain collected in n=25 crew-members overwintering at the German station in Antarctica "Neumayer III". Numbers refer to sessions as follows:0 = baseline, 1 = February, 2 = March, 3 = April, 4 = May, 5 = June, 6 = July, 7 = August, 8 = September, 9 = October.Data were recorded for 10 min in supine position in the morning.hr, heart rate; log, Logarithm; HF, High Frequency power; LF, Low Frequency power; LF/HF, LF to HF ratio; HFnu, High Frequency power in normalised units; LFnu, Low Frequency power in normalised units.Sex is dummy coded: men = 0; Women = 1
DOI: 10.17632/2pc36hgz7d
title: Data for: Eco-efficiency assessment of the electricity sector: evidence from 28 European Union countries

description: Data for: Eco-efficiency assessment of the electricity sector: evidence from 28 European Union countries
DOI: 10.17632/hnmhh6w2st
title: DataShare_Tn3

description: This dataset supports the article "Transposition with Tn3-family elements occurs through interaction with the β-sliding clamp processivity factor"
DOI: 10.6084/m9.figshare.13041860.v1
title: Croc_anticancer_Table1_data.pdf

description: Cytotoxic and anti-growth effects of crocodile organs on human cells.
DOI: 10.6084/m9.figshare.12420779.v1
title: Extended Data Figure 7.xlsx

description: Extended Data Figure 7.xlsx
DOI: 10.6084/m9.figshare.15104142.v2
title: Data for all participants

description: The original data included 1067 patients with type 2 diabetes and 1054 healthy controls.The data contained information about the gene locis being studied.
DOI: 10.6084/m9.figshare.15638832.v1
title: A standardized and statistically defensible framework for quantitative morphological analyses in taxonomic studies

description: Example datasets and Rscript for the publication "A standardized and statistically defensible framework for quantitative morphological analyses in taxonomic studies"<br>
DOI: 10.6084/m9.figshare.25216460.v2
title: Supplementary Material for: Feeling Alone Together: Loneliness in Older Adults with Cognitive Impairment and Their Family Caregivers with Low Mastery

description: Introduction. Loneliness in older persons with cognitive impairment (PCI) may beget loneliness in their family caregivers, depending on buffering resources caregivers possess. This study examined the association between loneliness in older persons with cognitive impairment (PCI) and loneliness experienced by their family caregivers, and the moderating role of caregiver mastery in this association.

Methods. Dyadic data from 135 PCI and their family caregivers in Singapore were analyzed using multivariable regression. Loneliness was measured by a three-item UCLA loneliness scale. Mastery was assessed using a seven-item Pearlin instrument. 

Results. Multivariable regression showed that PCI loneliness and caregiver loneliness were weakly associated, taking other covariates into account. The significant interaction between PCI loneliness and caregiver mastery revealed that PCI loneliness was associated with caregiver loneliness only when caregivers had low mastery. 

Discussion. Lonely PCI may share their feelings of loneliness with their caregivers, and this can lead to loneliness among caregivers if they have low mastery. Promoting caregiver mastery may help reduce caregiver loneliness, directly and indirectly as a buffer against PCI loneliness.