cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.6106274.v1
title: Kopie van DATABASE EM.xlsx

description: Single-handed general practices and group practices are the two predominant modes of primary care provision across European countries. In Belgium, single-handed practices have been the main form of primary care provision for years, but recently a trend is emerging towards introducing more group practices where a number of primary care physicians collaborate with other health professionals such as primary care nurses. The aim of this study was to measure the current support in general practices, and to gain insight in the general practitioner attitudes towards being supported by a practice nurse. Additionally, the aim was knowing to which extent general practitioners find practice nurses suitable to perform those tasks in their practice, that include the nurses’ entire area of expertise. A cross-sectional study was conducted among general practitioners who were currently working in a general practice in Flanders (Belgium). 271 general practitioners filled out an online questionnaire. 30% declared to be supported by a practice nurse. The majority (&gt;80%) of general practitioners showed positive attitudes towards collaboration with a practice nurse. General practitioners declared practice nurses to be most suitable to perform technical skills, and to provide patient education and health promotion advise.
DOI: 10.6084/m9.figshare.6106103
title: Supplementary Material for: No Muscle Depletion with High Visceral Fat as a Novel Beneficial Biomarker of Sorafenib for Hepatocellular Carcinoma

description: <b><i>Background:</i></b> Sorafenib is a standard therapy for patients with advanced hepatocellular carcinoma (HCC). However, no predictive biomarkers of sorafenib efficacy have been discovered. Herein, we investigated the impact of body composition, such as skeletal muscle and visceral fat, on the prognosis of advanced HCC patients treated with sorafenib. <b><i>Methods:</i></b> We enrolled 100 patients with advanced HCC treated with sorafenib. Prior to receiving sorafenib therapy, skeletal muscle index (SMI) and visceral fat area (VFA) were measured using computed tomography at the third lumbar vertebra and umbilical level, respectively. Muscle depletion was defined as an SMI value &lt; 42 cm<sup>2</sup>/m<sup>2</sup> in men and &lt; 38 cm<sup>2</sup>/m<sup>2</sup> in women. High VFA (H-VFA) was defined as a value ≥100 cm<sup>2</sup>. In addition to SMI and VFA, we also analyzed various clinical parameters as potential prognostic factors. <b><i>Results:</i></b> Multivariate analysis showed that having a tumor number &lt; 7 (hazard ratio [HR] = 0.409, <i>p</i> &lt; 0.001), absence of extrahepatic spread (EHS) (HR = 0.562, <i>p</i> &lt; 0.001), absence of muscle depletion (HR = 0.498, <i>p</i> = 0.006), and H-VFA (HR = 0.556, <i>p</i> = 0.031) were significant factors for long-term survival. Therefore, we evaluated the prognosis of those with no muscle depletion with H-VFA. The no muscle depletion with H-VFA group showed significantly longer survival than the other group (median survival time 15.6 vs. 11.0 months, <i>p</i> = 0.003). Multivariate analysis showed that having a tumor number &lt; 7 (HR = 0.454, <i>p</i> = 0.001), absence of EHS (HR = 0.511, <i>p</i> = 0.008), and no muscle depletion with H-VFA (HR = 0.454, <i>p</i> = 0.002) were significant predictors of survival. <b><i>Conclusions:</i></b> We identified no muscle depletion with H-VFA as a novel biomarker for advanced HCC patients treated with sorafenib.
DOI: 10.6084/m9.figshare.6106091
title: Supplemental gene list to accompany Figure 1j, Figure 2d. DeTCT 3' end sequencing carried out on various neural crest mutants at different time points

description: 3' end sequencing of multiple neural crest mutants; tfap2a, tfap2c, sox10, mitfa and yap1 at differing time points. Lists represent relevant pairwise comparisons.
DOI: 10.6084/m9.figshare.6106091.v1
title: Supplemental gene list to accompany Figure 1j, Figure 2d. DeTCT 3' end sequencing carried out on various neural crest mutants at different time points

description: 3' end sequencing of multiple neural crest mutants; tfap2a, tfap2c, sox10, mitfa and yap1 at differing time points. Lists represent relevant pairwise comparisons.
DOI: 10.6084/m9.figshare.6106088
title: On the influence of water conductivity, pH and climate on bryophyte assemblages in Catalan semi-natural springs

description: Bryophytes are some of the most sensitive biological indicators of environmental change. Springs have a significant presence of bryophytes and so are ideal habitats for studying their relationship with the environment. We tested whether bryophyte assemblages can be explained with macro-, meso- and micro-ecological variables (i.e. seasonal climate, altitude, water pH and conductivity) sampling bryophytes from 198 semi-natural springs distributed along montane regions in the north-eastern Iberian Peninsula. We tested the influence of environmental variables on bryophyte assemblages in springs using sparse Partial Least Squares. Our results show that variability in bryophyte assemblages is explained by seasonal climate (temperature and precipitation from winter, spring, summer and autumn and temperature and precipitation seasonality), altitude and water conductivity. The results obtained by the present study will be useful for predicting bryophyte diversity in springs using simple and easy to obtain variables such as climate, water pH and conductivity.
DOI: 10.6084/m9.figshare.6106088.v1
title: On the influence of water conductivity, pH and climate on bryophyte assemblages in Catalan semi-natural springs

description: Bryophytes are some of the most sensitive biological indicators of environmental change. Springs have a significant presence of bryophytes and so are ideal habitats for studying their relationship with the environment. We tested whether bryophyte assemblages can be explained with macro-, meso- and micro-ecological variables (i.e. seasonal climate, altitude, water pH and conductivity) sampling bryophytes from 198 semi-natural springs distributed along montane regions in the north-eastern Iberian Peninsula. We tested the influence of environmental variables on bryophyte assemblages in springs using sparse Partial Least Squares. Our results show that variability in bryophyte assemblages is explained by seasonal climate (temperature and precipitation from winter, spring, summer and autumn and temperature and precipitation seasonality), altitude and water conductivity. The results obtained by the present study will be useful for predicting bryophyte diversity in springs using simple and easy to obtain variables such as climate, water pH and conductivity.
DOI: 10.6084/m9.figshare.6106082
title: Supplemental gene lists to accompany Figure 1i, Figure 2e. FACS of neural crest cells at 22 hpf

description: FACS followed by RNA-Seq of sox10:mg cells in zebrafish at 22 hpf.
DOI: 10.6084/m9.figshare.6106082.v1
title: Supplemental gene lists to accompany Figure 1i, Figure 2e. FACS of neural crest cells at 22 hpf

description: FACS followed by RNA-Seq of sox10:mg cells in zebrafish at 22 hpf.
DOI: 10.6084/m9.figshare.6106079
title: Supplemental gene list to accompany Figure 4b-c and Supplemental Figure 2. RNA-Seq tfap2a;tfap2c mutants at 15 somites

description: RNA-Seq carried out on zebrafish embryos knockouts of tfap2a and tfap2c at the 15 somites stage. Gene lists are relevant pairwise comparisons carried out using DESeq2.
DOI: 10.6084/m9.figshare.6106079.v1
title: Supplimential gene list to accompany Figure 4b-c and Supplemental Figure 2. RNA-Seq tfap2a;tfap2c mutants at 15 somites

description: RNA-Seq carried out on zebrafish embryos knockouts of tfap2a and tfap2c at the 15 somites stage. Gene lists are relevant pairwise comparisons carried out using DESeq2.
DOI: 10.6084/m9.figshare.6106073
title: seedVicious

description: Computer program to predict microRNA targets, near target sites, and more. More information available at http://seedvicious.essex.ac.uk<br><br><br>
DOI: 10.6084/m9.figshare.6106073.v1
title: seedVicious

description: Computer program to predict microRNA targets, near target sites, and more. More information available at http://seedvicious.essex.ac.uk<br><br><br>
DOI: 10.6084/m9.figshare.6106067
title: Supplementary Material for: Meibomian Gland Dysfunction in Primary and Secondary Sjögren Syndrome

description: <b><i>Purpose:</i></b> We hypothesized that women with primary (pSS) and secondary Sjögren syndrome (sSS; with systemic lupus erythematosus [SLE] or rheumatoid arthritis [RA]) have meibomian gland dysfunction (MGD). We sought to test our hypothesis. <b><i>Methods:</i></b> Subjects with pSS, sSS + SLE, sSS + RA, and non-SS-related MGD were recruited from the Sjögren’s Syndrome Foundation or outpatient clinics at Tufts University School of Dental Medicine or Brigham and Women’s Hospital. The control population was recruited from the Greater Boston area. After providing written informed consent, the subjects underwent an eye examination and/or completed two questionnaires that assess symptoms of dry eye disease (DED). <b><i>Results:</i></b> Our results demonstrate that pSS and sSS patients have MGD. These subjects had meibomian gland orifice metaplasia, an increased number of occluded meibomian gland orifices, and a reduced quality of meibomian gland secretions. Further, patients with pSS, sSS + SLE, sSS + RA, and MGD had significant alterations in their tear film, lid margin, cornea, and conjunctiva. Symptoms of DED were increased ∼10-fold in all pSS, sSS, and MGD groups relative to controls. <b><i>Conclusions:</i></b> Our findings support our hypothesis and show that individuals with pSS, sSS + SLE, and sSS + RA have MGD. In addition, our study indicates that patients with pSS and sSS have both aqueous-deficient and evaporative DED.
DOI: 10.6084/m9.figshare.6106067.v1
title: Supplementary Material for: Meibomian Gland Dysfunction in Primary and Secondary Sjögren Syndrome

description: <b><i>Purpose:</i></b> We hypothesized that women with primary (pSS) and secondary Sjögren syndrome (sSS; with systemic lupus erythematosus [SLE] or rheumatoid arthritis [RA]) have meibomian gland dysfunction (MGD). We sought to test our hypothesis. <b><i>Methods:</i></b> Subjects with pSS, sSS + SLE, sSS + RA, and non-SS-related MGD were recruited from the Sjögren’s Syndrome Foundation or outpatient clinics at Tufts University School of Dental Medicine or Brigham and Women’s Hospital. The control population was recruited from the Greater Boston area. After providing written informed consent, the subjects underwent an eye examination and/or completed two questionnaires that assess symptoms of dry eye disease (DED). <b><i>Results:</i></b> Our results demonstrate that pSS and sSS patients have MGD. These subjects had meibomian gland orifice metaplasia, an increased number of occluded meibomian gland orifices, and a reduced quality of meibomian gland secretions. Further, patients with pSS, sSS + SLE, sSS + RA, and MGD had significant alterations in their tear film, lid margin, cornea, and conjunctiva. Symptoms of DED were increased ∼10-fold in all pSS, sSS, and MGD groups relative to controls. <b><i>Conclusions:</i></b> Our findings support our hypothesis and show that individuals with pSS, sSS + SLE, and sSS + RA have MGD. In addition, our study indicates that patients with pSS and sSS have both aqueous-deficient and evaporative DED.
DOI: 10.6084/m9.figshare.6106058
title: Triaxial_Tests

description: In order to investigate the mechanical behavior of MHBS, triaxial tests are done combined with measures of compressional wave velocity. The last one has been after compared to Helgurd's model to study pore habit of MHBS.<br>
DOI: 10.6084/m9.figshare.6106058.v2
title: Triaxial_Tests

description: In order to investigate the mechanical behavior of MHBS, triaxial tests are done combined with measures of compressional wave velocity. The last one has been after compared to Helgurd's model to study pore habit of MHBS.<br>
DOI: 10.6084/m9.figshare.6106058.v1
title: Triaxial_Tests

description: In order to investigate the mechanical behavior of MHBS, triaxial tests are done combined with measures of compressional wave velocity. The last one has been after compared to Helgurd's model to study pore habit of MHBS.<br>
DOI: 10.6084/m9.figshare.6106055
title: Supplementary Material for: Global Scientific Production on Illicit Drug Addiction: A Two-Decade Analysis

description: <b><i>Aims:</i></b> Addiction science has made great progress in the past decades. We conducted a scientometric study in order to quantify the number of publications and the growth rate globally, regionally, and at country levels. <b><i>Methods:</i></b> In October 2015, we searched the Scopus database using the general keywords of addiction or drug-use disorders combined with specific terms regarding 4 groups of illicit drugs – cannabis, opioids, cocaine, and other stimulants or hallucinogens. All documents published during the 20-year period from 1995 to 2014 were included. <b><i>Results:</i></b> A total of 95,398 documents were retrieved. The highest number of documents were on opioids, both globally (60.1%) and in each of 5 continents. However, studies on cannabis showed a higher growth rate in the last 5-year period of the study (2010–2014). The United States, the United Kingdom, Germany, Canada, Australia, France, Spain, Italy, China, and Japan – almost all studies were from high-income countries – occupied the top 10 positions and produced 81.4% of the global science on drug addiction. <b><i>Conclusion:</i></b> As there are important socio-cultural differences in the epidemiology and optimal clinical care of addictive disorders, it is suggested that low- and more affected middle-income countries increase their capacity to conduct research and disseminate the knowledge in this field.
DOI: 10.6084/m9.figshare.6106004
title: Ledesma_et_al_2018_WRR_Dataset.xlsx

description: Final derived data reported in the figures of the paper entitled "Stream dissolved organic matter composition reflects the riparian zone, not upslope soils in boreal forest headwaters", by Ledesma et al. published in Water Resources Research in 2018.<br>
DOI: 10.6084/m9.figshare.6105980
title: zipFile

description: Test fichier zip<br>
DOI: 10.6084/m9.figshare.6105980.v1
title: zipFile

description: Test fichier zip<br>
DOI: 10.6084/m9.figshare.6105971
title: Negative affect varying in motivational intensity influences scope of memory

description: Emotions influence cognitive processes involved in memory. While some research has suggested that cognitive scope is determined by affective valence, recent models of emotion–cognition interactions suggest that motivational intensity, rather than valence, influences these processes. The present research was designed to clarify how negative affects differing in motivational intensity impact memory for centrally or peripherally presented information. Experiments 1 & 2 found that, relative to a neutral condition, high intensity negative affect (anger) enhances memory for centrally presented information. Experiment 3 replicated this effect using another high intensity negative affect (threat). Experiment 4 extended this by finding that, relative to a neutral condition, low intensity negative affect (sadness) enhanced memory for peripherally presented information. Finally, in Experiment 5, the effects of sadness and threat on scope of memory were directly compared, finding that threat narrowed scope of memory, while sadness broadened scope of memory. Together, these results provide additional support for the motivational dimensional model of cognitive scope, in that high intensity emotions narrow cognitive scope, while low intensity emotions broaden cognitive scope.
DOI: 10.6084/m9.figshare.6105971.v1
title: Negative affect varying in motivational intensity influences scope of memory

description: Emotions influence cognitive processes involved in memory. While some research has suggested that cognitive scope is determined by affective valence, recent models of emotion–cognition interactions suggest that motivational intensity, rather than valence, influences these processes. The present research was designed to clarify how negative affects differing in motivational intensity impact memory for centrally or peripherally presented information. Experiments 1 & 2 found that, relative to a neutral condition, high intensity negative affect (anger) enhances memory for centrally presented information. Experiment 3 replicated this effect using another high intensity negative affect (threat). Experiment 4 extended this by finding that, relative to a neutral condition, low intensity negative affect (sadness) enhanced memory for peripherally presented information. Finally, in Experiment 5, the effects of sadness and threat on scope of memory were directly compared, finding that threat narrowed scope of memory, while sadness broadened scope of memory. Together, these results provide additional support for the motivational dimensional model of cognitive scope, in that high intensity emotions narrow cognitive scope, while low intensity emotions broaden cognitive scope.
DOI: 10.6084/m9.figshare.6105956
title: deuxFichiers

description: Test avec plusieurs fichiers<br>
DOI: 10.6084/m9.figshare.6105956.v1
title: deuxFichiers

description: Test avec plusieurs fichiers<br>
DOI: 10.6084/m9.figshare.6105875
title: Supplementary Material for: Factors Associated with Functional Performance among Patients on Hemodialysis in Taiwan

description: <b><i>Background/Aims:</i></b> We investigated factors associated with functional performance in hemodialysis (HD) patients as well as their relationships with mortality. <b><i>Methods:</i></b> We enrolled 790 HD patients who were followed up from 2009 to 2013. Functional performance was evaluated by Karnofsky Performance Status Scale (KPSS) scores. We examined the associations of clinical variables and all-cause mortality with KPSS scores. <b><i>Results:</i></b> Of the participants, 460 had high KPSS scores (range 90–100) and 330 had low KPSS scores (below 80). On multivariate analysis, age and weekly HD sessions were associated with significantly increased odds of a lower KPSS score (age: OR 1.05, 95% CI 1.04–1.07, <i>p</i> &lt; 0.001; weekly HD: OR 2.10, 95% CI 1.37–3.21, <i>p</i> = 0.001). A low KPSS score was a significant predictor of increased all-cause mortality (hazard ratio 1.49; 95% CI 1.02–2.16, <i>p</i> = 0.037), as determined using Cox regression analysis. <b><i>Conclusion:</i></b> Functional performance was associated with clinical variables and all-cause mortality in HD patients.
DOI: 10.6084/m9.figshare.6105854
title: Nonlinear spectroscopy of plasmonic nanoparticles

description: The plasmon resonance of a metal nanoparticle increases the optical field amplitude in and around the particle with respect to the incoming wave. In consequence, optical effects that are nonlinear in their field amplitude profit from this increased field. In general, a plasmonic structure can react nonlinearly by itself and it can also enhance the effect of the nonlinearity in its environment, which we consider as plasmonic nanoantenna. In this paper, we review third-order nonlinear effects such as third-harmonic generation, pump-probe spectroscopy, coherent anti-Stokes Raman scattering and four-wave mixing of and near plasmonic nanostructures. All these processes are described by very similar equations for the nonlinear polarization, but the underling physics differs.
DOI: 10.6084/m9.figshare.6105854.v1
title: Nonlinear spectroscopy of plasmonic nanoparticles

description: The plasmon resonance of a metal nanoparticle increases the optical field amplitude in and around the particle with respect to the incoming wave. In consequence, optical effects that are nonlinear in their field amplitude profit from this increased field. In general, a plasmonic structure can react nonlinearly by itself and it can also enhance the effect of the nonlinearity in its environment, which we consider as plasmonic nanoantenna. In this paper, we review third-order nonlinear effects such as third-harmonic generation, pump-probe spectroscopy, coherent anti-Stokes Raman scattering and four-wave mixing of and near plasmonic nanostructures. All these processes are described by very similar equations for the nonlinear polarization, but the underling physics differs.
DOI: 10.6084/m9.figshare.6105827
title: DATASET [Thia 2018 J Anim Ecol]: Bathygobius cocosensis trait covariances

description: Data, scripts, and results associated with the publication:<br><br>Thia et al. (2018) Larval traits show temporally consistent constraints, but are decoupled from postsettlement juvenile growth, in an intertidal fish. Journal of Animal Ecology.
DOI: 10.6084/m9.figshare.6105827.v1
title: Thia et al. (2018) J Anim Ecol: Larval traits show temporally consistent constraints, but are decoupled from post-settlement juvenile growth, in an intertidal fish

description: Data, scripts, and results associated with this publication.<br>
DOI: 10.6084/m9.figshare.6105827.v2
title: Thia et al. 2018 J Anim Ecol: Larval traits show temporally consistent constraints, but are decoupled from post-settlement juvenile growth, in an intertidal fish

description: Data, scripts, and results associated with this publication.<br>
DOI: 10.6084/m9.figshare.6105827.v3
title: Thia et al. (2018) J Anim Ecol: Larval traits show temporally consistent constraints, but are decoupled from post-settlement juvenile growth, in an intertidal fish

description: Data, scripts, and results associated with this publication.<br>
DOI: 10.6084/m9.figshare.6105827.v4
title: DATASET (Thia et al. 2018 J Anim Ecol): Larval traits show temporally consistent constraints, but are decoupled from post-settlement juvenile growth, in an intertidal fish.

description: Data, scripts, and results associated with this publication.<br>
DOI: 10.6084/m9.figshare.6105827.v5
title: DATASET [Thia et al. 2018 J Anim Ecol]: Larval traits show temporally consistent constraints, but are decoupled from post-settlement juvenile growth, in an intertidal fish.

description: Data, scripts, and results associated with this publication.<br>
DOI: 10.6084/m9.figshare.6105827.v6
title: DATASET [Thia et al. 2018 J Anim Ecol]: Larval traits show temporally consistent constraints, but are decoupled from post-settlement juvenile growth, in an intertidal fish

description: Data, scripts, and results associated with this publication.<br>
DOI: 10.6084/m9.figshare.6105827.v7
title: DATASET [Thia et al. 2018 J Anim Ecol]: Larval traits show temporally consistent constraints, but are decoupled from post-settlement juvenile growth, in an intertidal fish

description: Data, scripts, and results associated with this publication.<br>
DOI: 10.6084/m9.figshare.6105827.v9
title: DATASET [Thia 2018 J Anim Ecol]: Bathygobius cocosensis trait covariances

description: Data, scripts, and results associated with the publication:<br><br>Thia et al. (2018) Larval traits show temporally consistent constraints, but are decoupled from postsettlement juvenile growth, in an intertidal fish. Journal of Animal Ecology.
DOI: 10.6084/m9.figshare.6105827.v8
title: DATASET: Thia et al. (2018) J Anim Ecol

description: Data, scripts, and results associated with the publication:<br><br>Thia et al. (2018) Larval traits show temporally consistent constraints, but are decoupled from postsettlement juvenile growth, in an intertidal fish. Journal of Animal Ecology.
DOI: 10.6084/m9.figshare.6105437
title: MOESM7 of Clostridium thermocellum LL1210 pH homeostasis mechanisms informed by transcriptomics and metabolomics

description: Additional file 7. Extracellular amino acid concentrations in media from C. thermocellum LL1210 chemostats that were sampled when pH values were pH 6.48, pH 6.24, pH 6.12, and below. Demonstrations of data homoscedasticity for T tests.