cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.25606/surf.578c6039-505561a0
title: The Cosmogrid Simulation: Statistical Properties of Small Dark Matter Halos (2048-032)

description: We present the results of the "Cosmogrid" cosmological N-body simulation suites based on the concordance LCDM model. The Cosmogrid simulation was performed in a 30 Mpc box with 2048³ particles. The mass of each particle is 1.28x10^5 Msun, which is sufficient to resolve ultra-faint dwarfs. We found that the halo mass function shows good agreement with the Sheth & Tormen fitting function down to ~10^7 Msun. We have analyzed the spherically averaged density profiles of the three most massive halos which are of galaxy group size and contain at least 170 million particles. The slopes of these density profiles become shallower than -1 at the inner most radius. We also find a clear correlation of halo concentration with mass. The mass dependence of the concentration parameter cannot be expressed by a single power law, however a simple model based on the Press-Schechter theory proposed by Navarro et al. gives reasonable agreement with this dependence. The spin parameter does not show a correlation with the halo mass. The probability distribution functions for both concentration and spin are well fitted by the log-normal distribution for halos with the masses larger than ~10^8 Msun. The subhalo abundance depends on the halo mass. Galaxy-sized halos have 50% more subhalos than ~10^11 Msun halos have. This is snapshot 032 of the 2048³ resolution collection.
DOI: 10.25606/surf.578c6039-9343eeea
title: The Cosmogrid Simulation: Statistical Properties of Small Dark Matter Halos (2048-030)

description: We present the results of the "Cosmogrid" cosmological N-body simulation suites based on the concordance LCDM model. The Cosmogrid simulation was performed in a 30 Mpc box with 2048³ particles. The mass of each particle is 1.28x10^5 Msun, which is sufficient to resolve ultra-faint dwarfs. We found that the halo mass function shows good agreement with the Sheth & Tormen fitting function down to ~10^7 Msun. We have analyzed the spherically averaged density profiles of the three most massive halos which are of galaxy group size and contain at least 170 million particles. The slopes of these density profiles become shallower than -1 at the inner most radius. We also find a clear correlation of halo concentration with mass. The mass dependence of the concentration parameter cannot be expressed by a single power law, however a simple model based on the Press-Schechter theory proposed by Navarro et al. gives reasonable agreement with this dependence. The spin parameter does not show a correlation with the halo mass. The probability distribution functions for both concentration and spin are well fitted by the log-normal distribution for halos with the masses larger than ~10^8 Msun. The subhalo abundance depends on the halo mass. Galaxy-sized halos have 50% more subhalos than ~10^11 Msun halos have. This is snapshot 030 of the 2048³ resolution collection.
DOI: 10.14457/cu.the.2012.662
title: The role of Thai tourism in promoting Thai-Vietnamese relations

description: This thesis argues that tourism has contributed greatly to the better relationship between Thailand and Vietnam, especially on people – to – people relations. In it, the factors that lead to the growth of Thai tourism in Vietnam will also be investigated. Then, it will analyze to what extent Thai tourism helps shape Vietnamese attitudes and understanding of Thailand as well as how Thai tourism contributes to the development of Thai – Vietnamese relations. The research will utilize both quantitative and qualitative methods but is mainly based on qualitative research method including documentary research, questionnaire and interviews. Findings show that the history of long-standing relationship between Vietnam and Thailand has witnessed many ups and downs stage. In some periods, it was very complicated and was governed by prejudices and suspicions. However, since diplomatic relation between two countries was officially established on August 6, 1976, the Thai – Vietnamese relationship has improved significantly. A better understanding between the people of the two nations has contributed to better diplomatic relations. This is partly due to the development of Thai tourism in the Vietnam market. Thai tourism helps build a strong and beautiful image for the country. The study also reveals the contribution of Thai tourism to the development of Thai – Vietnamese relationship and its role in changing attitudes and understandings of Vietnamese tourists toward Thailand.
DOI: 10.14457/cu.the.2012.663
title: Development of phasor measurement unit conformed to IEEE C37.118 standard

description: Phasor is an electrical complex value containing of magnitude root mean square value and phase angle in polar form represents instantaneous electrical sinusoidal waveform. We propose an idea to develop phasor measurement device that conformed accuracy to IEEE C37.118 standard for 50 Hz power system without communication part.
DOI: 10.14457/cu.the.2012.664
title: The effects of cognitive academic language learning approach on English oral communication ability of bible college students

description: The objectives of this study were to 1) investigate the effects of Cognitive Academic Language Learning Approach on English oral communication ability of Bible College students 2) explore students’ opinions towards the components of CALLA. The participants were college students at Bangkok Bible Seminary. The Paired-Samples T-test was applied to investigate the differences between the mean scores from the pre and post English Oral Communication Ability Test. The interview was used to explore into the students’ opinion towards the CALLA. The results of the analyses revealed that there was a significant difference between the mean scores from the pre and posttest. In other words, the Bible college students improved their English oral communication ability after the use of CALLA. The result of the interview showed both positive and negative opinions towards the components of CALLA which are content, language, and strategy as well as the instructional process. The interview showed that the impacts of the English oral communication ability of the students are the content motivation, their confidence and willingness to communicate, the use of strategies, as well as, the collaboration in class activities.
DOI: 10.14457/cu.the.2012.665
title: Integrated approach for rural community development : the case study of Saemaul Undong during 1970-1979

description: The purpose of this research is to study South Korea’s rural development program or Saemaul Undong with the focus on the integrated approach strategy for rural development, by analyzing the secondary academic data for Saemaul Undong and other related information collected through various sources including finding from research studies, books, journals and online articles. The study is concentrating on the early phase which is during 1970-1979 since it had the most impressive outcome. The findings of this study reveal the significant integrated approach of Saemaul Undong’s strategy which is, the combination of bottom-up and top-down, a profound factor to achieve impressive outcome of South Korea’s rural development in 1970-1979. However, culturally, under Asian rural conditions, it may be difficult for rural people to start the development project. Investment and development in rural areas would be inefficient if the rural people were not ready to make effective use of such investment. Therefore, to successfully achieve in rural development and investment, the Korean government employed a top-down approach in the initial stage to shape a basic groundwork for the bottom-up approach from rural people in the latter stage. There are negative perspectives towards the program, such as it could not stop the rural-out migration and it was established as political apparatus for President Park Chung Hee. In spite of that criticism, it succeeded in the improvement of life and better standard of living and increased rural household income as it was first proposed with the strong support for the government and the participation from rural people.
DOI: 10.14457/cu.the.2012.666
title: Effects of substituents on the 5-position of deoxyuridinemonophosphate on the thiolate addition in thymidylate synthase using QM/MM technique

description: Thymidylate synthase (TS) is an enzyme that catalyses the reductive methylation of dUMP to produce dTMP in the thymine nucleotide synthesis. The Michael addition and ternary covalent complex formation are considered as important steps involved in the inhibition mechanism of a known anticancer drug, 5-FU. The effect of functional group substitution on the C-5 position of dUMP substrate with halogen atoms (F-, Cl- and Br- ) and electron withdrawing (CN-, NO₂-) and donating (NH₂-, OH-) groups towards the TS stability is investigated by means of molecular dynamics simulation technique. The simulated results showed that an additionally unique hydrogen bond between the substituted group of dUMP analogues and the hydroxyl group of Y94 was observed in most systems except CldUMP and BrdUMP analogues. The MM/PBSA binding free energy provides the orders of averaged binding affinity are: CldUMP ~ FdUMP &gt; dUMP &gt; BrdUMP for halogen analogues and CNdUMP ~ NO₂dUMP &gt; OHdUMP ~ NH₂dUMP for electron withdrawing and donating analogues. Based on the B3LYP/6-31+G*-CHARMM hybrid method, the Michael addition and ternary covalent complex formation between dUMP and mTHF substrates to form the methylene bridging intermediate is determined via a concerted mechanism. By following the several tests of QM/MM approaches, the SCS-MP2 method with aug-cc-pVTZ basis sets is selected for reaction energy profile evaluation. Due to the close of activation energy with FdUMP anticancer drug and high affinity of the binding in CldUMP analogue, therefore, we proposed that the CldUMP analogue has a potent to be the new candidate inhibitor against thymidylate synthase function.
DOI: 10.14457/cu.the.2012.667
title: Virulence gene analysis and pathogenicity of Thai isolated mycoplasma gallisepticum

description: The four virulence genes (pvpA, gapA, mgc2 and LP (MGA_0319)) were analyzed from 19 isolates of Mycoplasma gallisepticum (MG) from central, eastern and western parts of Thailand and 2 reference strains including F (vaccine strain) and S6 (ATCC® 15302TM) by PCR (exp. 1). Results revealed the variation in gapA and pvpA genes existence. The gapA and pvpA genes were found in 15 and 4 of 19 isolates, respectively. Whereas, mgc2 and LP genes were detected in all isolates. PCR results of 2 reference strains were positive for all 4 genes. Interestingly, all 4 gapA-negative isolates also performed pvpA-negative PCR results. Additionally, 3 isolates were obtained from the eastern and 1 from western parts; on the other hand, all MG isolates from the central part showed gapA-positive results. The pathogenicity study of 3 Thai MG isolates (58/46, 31/46 and 54/46) and 2 reference strains compared with the control group were determined in chickens (exp. 2) and chicken embryonated eggs (CEE) (exp. 3). The results showed that the pathogenicity study in chickens and CEE were similar. The 58/46 isolate (from the central part, gapA and pvpA-positive) caused the most severe clinical signs, lesion scores and mortality compared with 31/46 and 54/46 (from eastern part, gapA-positive, pvpA-negative) and reference strains did. This experiment suggested that pvpA-negative isolates produced the lower virulent than pvpA-positive isolates.
DOI: 10.14457/cu.the.2012.668
title: Purification of free lutein from marigold flower by preparative chromatography and particle formation of free lutein by supercritical carbon dioxide

description: Marigold flowers is a rich source of lutein, a type of xanthophylls that has been demonstrate to reduce the risk of ocular diseases and provide protective effect against cardiovascular diseases and stroke, etc. However, to exhibit some of these pharmaceutical properties, the compound should be of high purity. Liquid chromatography has widely been used to effectively separate lutein from other impurities for analytical purposes. However, only few reports were found on larger preparative scale. The first part of this work therefore aims to develop a protocol for preparative scale liquid chromatography purification of free lutein derived from marigold flowers. With silica gel as a stationary and mixture of hexane:ethyl acetate at 70:30 volume ratio (10 ml/min flow rate) as a mobile phase, as high as 97.1 % purity lutein could be obtained. Unfortunately, other than the purity issue, one other limitation to the applicability of the compound is its poor water solubility. This causes low oral and dermal bioavailability. To reduce this problem, supercritical anti-solvent (SAS) micronization of lutein particles were investigated using carbon dioxide (CO2) as anti-solvent. In the second part of this work, because their binary phase equilibrium data with CO2 are available in literature, the possibility to use dichloromethane (DCM) and ethanol as solvents in which lutein was dissolved prior to the SAS experiments was investigated. The reduction in size of lutein from 202.3 µm of unprocessed lutein to 1.58 µm and 902 nm could be achieved by SAS technique using DCM and ethanol, respectively. In addition, the last part of this work aims to demonstrate the feasibility of SAS micronization of lutein dissolved in mixture of hexane and ethyl acetate (70:30 v/v). The solubility of the SAS micronized lutein particles in aqueous solution was found to increase significantly from being almost insoluble to having approximately 20% solubility. Success in SAS micronization in hexane:ethyl acetate solvent mixture, which was used as a mobile phase for the chromatographic purification, implies that a step of solvent evaporation from the eluted samples and re-dissolving the dried sample into another organic solvent can be omitted. By this, not only the process cost can be reduced, the degradation of lutein during complicated processing steps can also be minimized.
DOI: 10.14457/cu.the.2012.669
title: Evalution of tree frog antimicrobial peptide production by bacterial and plant expression system

description: Antimicrobial peptides play a role in innate immune system in all living organisms. Rhacoporin-2, a novel AMP from the skin secretion of Rhacophorus feae, shows an antimicrobial activity against both Gram-positive and Gram-negative bacteria. Contrastingly, it is relatively unharmful to mammalian red blood cell. Thus, it has a potential to be used as pharmaceutical agent. SUMO fusion system is employed for Rhacoporin-2 production. Therefore, the objective of this study is to evaluate the recombinant peptide, SUMO-Rhacoporin2, production by bacterial expression system and plant expression system. In Escherichia coli system, the total 131 µg/L of Rhacoporin2 with 85% purity was produced and the peptide exhibited the antibacterial activity against Salmonella Typhimurium at 8 µM. Hence, SUMO fusion system was effective for antimicrobial peptide production by bacterial system. For the recombinant peptide production in 2 plant hosts, Lemna minor and Arabidopsis thaliana, the results showed that the very low amount of recombinant peptide, 44.8 µg, was synthesized from 100 mg fresh duckweed, whereas, SUMOstar fusion tag for peptide production was unsuccessful in Arabidopsis. Therefore, SUMO fusion system was ineffective in these two species. However, plant system is still promising due to the low cost of production for therapeutic agents.
DOI: 10.14457/cu.the.2012.670
title: Phytochemistry and bioactivities of salacia verrucosa and ficus foveolata stems

description: Chemical investigation of the stems of Salacia verrucosa Wight (family Celastraceae) led to the isolation of one new (21α-hydroxyfriedelane-1,3-dione) and three known 1,3-diketofriedelane triterpenes (friedelane-1,3-dione, 26-hydroxyfriedelane-1,3-dione and 30-hydroxyfriedelane-1,3-dione), three friedelane-type triterpenes (friedelin, kokoonol and 21α-hydroxyfriedelan-3-one), and one oleanane-type triterpene (3β,22α-dihydroxyolean-12-en-29-oic acid). From the stems of Ficus foveolata (Wall. ex Miq.) Miq. (family Moraceae), two new (foveolide A and foveoeudesmenone) and two known eudesmane-type sesquiterpenes [4(15)-eudesmene-1β,6α-diol and 4(15)-eudesmene-1β,5α-diol], a new sesquiterpenoid dimer (foveolide B), one new (foveospirolide) and one known phenolic compound (ethyl rosmarinate), together with three known triterpenes (friedelin, taraxerol and betulin) were isolated. The chemical structures of these plant constituents were determined by spectroscopic analyses, including UV, IR, MS and NMR, and comparison with previously reported data. Friedelane-1,3-dione was strongly cytotoxic against human colon cancer cell line (SW620) with an IC [subscript 50] value of 2.02 µM, whereas 26-hydroxyfriedelane-1,3-dione and 21α-hydroxyfriedelan-3-one were moderately cytotoxic against colon, liver (HepG2) and gastric (KATO-III) cancer cell lines. 26-Hydroxyfriedelane-1,3-dione also exhibited moderate cytotoxicity against lung (CHAGO) and breast (BT474) cancer cell lines. Foveolide A was moderately cytotoxic against colon, liver, breast and gastric cancer cell lines, while foveolide B was specifically cytotoxic toward colon cancer cell line. In addition, foveolide A exhibited anti-tuberculosis activity against Mycobacterium tuberculosis with a minimum inhibitory concentration of 200 µM.
DOI: 10.25606/surf.578c6039-9e69e5df
title: The Cosmogrid Simulation: Statistical Properties of Small Dark Matter Halos (2048-028)

description: We present the results of the "Cosmogrid" cosmological N-body simulation suites based on the concordance LCDM model. The Cosmogrid simulation was performed in a 30 Mpc box with 2048³ particles. The mass of each particle is 1.28x10^5 Msun, which is sufficient to resolve ultra-faint dwarfs. We found that the halo mass function shows good agreement with the Sheth & Tormen fitting function down to ~10^7 Msun. We have analyzed the spherically averaged density profiles of the three most massive halos which are of galaxy group size and contain at least 170 million particles. The slopes of these density profiles become shallower than -1 at the inner most radius. We also find a clear correlation of halo concentration with mass. The mass dependence of the concentration parameter cannot be expressed by a single power law, however a simple model based on the Press-Schechter theory proposed by Navarro et al. gives reasonable agreement with this dependence. The spin parameter does not show a correlation with the halo mass. The probability distribution functions for both concentration and spin are well fitted by the log-normal distribution for halos with the masses larger than ~10^8 Msun. The subhalo abundance depends on the halo mass. Galaxy-sized halos have 50% more subhalos than ~10^11 Msun halos have. This is snapshot 028 of the 2048³ resolution collection.
DOI: 10.14457/cu.the.2012.671
title: Morphotectonic analysis of Mae Ping Fault Zone in Changwat Tak and Changwat Kamphaeng Phet, Northwestern Thailand

description: The Mae Ping fault zone in Changwat Tak and Changwat Kamphaeng phet was selected for analysis of morphotectonic and tectonic interpretation. The application of remote-sensing data was conducted toward the present study. Morphotectonic analysis and tectonic interpretation of the Mae Ping fault zone are the main task of this study. In this study, Digital elevation model and Landsat-7 ETM+ bands 4-5-7 were chosen to create the false color composite. The visual images interpretation combined with geomorphic indices was conducted to analyze the morphotectonic that were created in GIS database. Field investigations were also used to test for accuracy of the lineament interpretation and values of geomorphic indices. The analysis found that lineament patterns are mainly trend in NW-SE azimuth direction with a total length of about 230 kilometers. From the calculated data reveal that mountain front sinuosity index represent low values from 1.04 to 1.77, Valley floor width to height ratio show very low values from 0.30 to 2.66, and Stream length gradient index display very high values. Geomorphological features like offset streams, triangular facets, and shutter ridges show that the tectonic controls in the area. Morphotectonic evidences such as straight mountain front, V-shape valley and narrow valley floor, and abruptly change slope of several streams and result of geomorphic indices indicate that tectonic activities are highest in zone 3 of the study areas which are control by strike-slip fault and normal fault. The final results from this research can be used as a spatial data for supporting active faults study in Thailand including geological hazard warning and city planning for much better efficient management in the future.
DOI: 10.14457/cu.the.2012.672
title: Bioavailability and fractionation of Cd and Zn in contaminated soils amended by filter cake, vinasse and boiler ash from ethanol production plant

description: Boiler ash (BA), filter cake (FC), and vinasse (VN) are three major wastes produced from ethanol production processes. Waste utilization from ethanol production as soil amendments and metal immobilizing agents is one of a promising and sustainable options to help utilize materials effectively, reduce waste disposal, and adds values to these waste-products. As a consequence, this research was carried out by adding BA, FC, and VN at different ratio (3% w/w) in two different Cd and Zn concentration levels of low Cd (LCdS) and high Cd (HCdS) contaminated soils, respectively for 3 months. The results showed that the addition of single BA and FC (3% w/w), and a combination of 1.5% BA and 1.5% VN (w/w) caused the significant reduction in the bioavaialble Cd concentration (BCR1+2) during the first few week of the soil pot experiment. Based on this, a four-month pot experiment of sugarcane (Saccharum officinarum L.) cultivation was further conducted to determine the effect of these waste-products on sugarcane growth, metal accumulation in sugarcane, and fractionation of Cd and Zn in soils by the BCR sequential extraction. Two studied soils (LCdS and HCdS) showed different results. LCdS showed the improved sugarcane biomass production; 6 and 3-fold higher for the aboveground parts (from 8.46 to 57.6 g plant-1) and root (from 2.10 to 6.59 g plant-1), respectively as compared to non-amended soil, while no positive effect was observed in HCdS. There was no significant difference in metal uptake by sugarcane among different treatments in LCdS (0.44 to 0.52 mg Cd kg-1 and 39.9 to 48.1 mg Zn kg-1), however, the reduction of the most bioavailable Cd concentration (BCR1+2) in the treated soils (from 35.4% to 54.5%) and the transformation of Cd into organic-matter bound fraction (BCR3) at the end of the pot experiment highlighted the beneficial effects of these waste-products in promoting the sugarcane growth and Cd stabilization in LCdS. Alternatively, the addition of single BA and FC (3% w/w) to HCdS contributed to the reduction of Cd uptake in aboveground part of sugarcane (61.9% and 48.9%, respectively) and bioavailability of Cd (BCR1+2) in the treated soils, but not significantly at *p&lt;0.05 (6.8% and 4.0%, respectively). No metal toxicity visually seen in both studied soils and low metal translocation to sugarcanes was observed as indicated by low translocation index (TF&lt;1). The results from this study could provide useful information for the recycling sugarcane waste-products generated from ethanol production plant on agricultural lands for improving sugarcane productivity and predicting metal mobility in the future use.