cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q23f4r7s
title: BindingDB Entry 50044593: Discovery and optimization of pyrrolo[1,2-a]pyrazinones leads to novel and selective inhibitors of PIM kinases.

description: Small molecule binding data for protein 40S ribosomal protein S27, AKT/p21CIP1, ALK tyrosine kinase receptor, Activator of S phase kinase DBF4/Cell division cycle 7-related protein kinase, Aurora kinase B/Inner centromere protein, CDC7/DBF4 (Cell division cycle 7-related protein kinase/Activator of S phase kinase), Cyclin-dependent kinase 2, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), Cytochrome P450 3A, Ephrin receptor, Epidermal growth factor receptor, Fibroblast growth factor receptor 1, Focal adhesion kinase 1/vascular endothelial growth factor receptor 3, Glycogen synthase kinase-3, Hepatocyte growth factor receptor, High affinity immunoglobulin gamma Fc receptor I, Inhibitor of NF-kappa-B kinase (IKK), Insulin receptor, JAK2/TYK2, JAK3/JAK1, Kinesin-1 heavy chain/ Tyrosine-protein kinase receptor RET, MAP kinase ERK2, MAP kinase signal-integrating kinase 2, MAP kinase-activated protein kinase 2, Maternal embryonic leucine zipper kinase (MELK), Mitogen-activated protein kinase 14, Mitotic checkpoint serine/threonine-protein kinase BUB1, Neurotrophic tyrosine kinase receptor, PKC alpha and beta-2, Pancreatic endoplasmic reticulum kinase (PERK), Proto-oncogene tyrosine-protein kinase ROS, Pyruvate dehydrogenase kinase isoenzyme 1 (PDK1), SRC, Serine/threonine-protein kinase Aurora, Serine/threonine-protein kinase Chk1, Serine/threonine-protein kinase EEF2K, Serine/threonine-protein kinase MST4, Serine/threonine-protein kinase NEK6, Serine/threonine-protein kinase NIM1, Serine/threonine-protein kinase PAK 4, Serine/threonine-protein kinase PIM, Serine/threonine-protein kinase PLK1, Serine/threonine-protein kinase haspin, Tyrosine kinase non-receptor protein 2, Tyrosine-protein kinase ABL1, Tyrosine-protein kinase BRK, Tyrosine-protein kinase JAK1, Tyrosine-protein kinase JAK2, Tyrosine-protein kinase Kit (Kit), Tyrosine-protein kinase SYK, Tyrosine-protein kinase ZAP-70, Tyrosine-protein kinase receptor FLT3, and Vascular endothelial growth factor receptor 2, Uniprot O00311, O00418, O14757, O14920, O14965, O43683, O60674, O96013, P00519, P00533, P04629, P05771, P06213, P06239, P07948, P07949, P08581, P08684, P08922, P10635, P10721, P11309, P11362, P11712, P12314, P23458, P24941, P28482, P29317, P29597, P31749, P35916, P35968, P36888, P42677, P43403, P43405, P49137, P49841, P52333, P53350, Q05397, Q07912, Q13882, Q14680, Q15118, Q16539, Q86V86, Q8IY84, Q8TF76, Q96GD4, Q9HBH9, Q9HC98, Q9NZJ5, Q9P1W9, Q9P289, Q9UBU7, and Q9UM73
DOI: 10.7270/q23t9jzd
title: BindingDB Entry 50046086: Novel spirohydantoin derivative as a potent multireceptor-active antipsychotic and antidepressant agent.

description: Small molecule binding data for protein Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor and Serotonin (5-HT) receptor, Uniprot P14842, P19327, P32305, and P61169
DOI: 10.7270/q24f1sf2
title: BindingDB Entry 50045570: Discovery of novel spiro 1,3,4-thiadiazolines as potent, orally bioavailable and brain penetrant KSP inhibitors.

description: Small molecule binding data for protein Kinesin-like protein 1, Uniprot P52732
DOI: 10.7270/q2571dfr
title: BindingDB Entry 50043443: TBA

description: Small molecule binding data for protein Cytochrome P450 1A, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), and Metabotropic glutamate receptor 5, Uniprot P05177, P10635, P11712, and P41594
DOI: 10.7270/q2571dtp
title: BindingDB Entry 50046595: 1,3,7-Triethyl-substituted xanthines--possess nanomolar affinity for the adenosine A1 receptor.

description: Small molecule binding data for protein Adenosine Receptors A2a (A2a) and Adenosine receptor A1, Uniprot P25099 and P30543
DOI: 10.7270/q27m09pp
title: BindingDB Entry 50046085: Fragmentation of GW4064 led to a highly potent partial farnesoid X receptor agonist with improved drug-like properties.

description: Small molecule binding data for protein Bile acid receptor FXR, Uniprot Q96RI1
DOI: 10.7270/q2862j5s
title: BindingDB Entry 50045569: Novel thiazolo[3,2-b]-1,2,4-triazoles derived from naproxen with analgesic/anti-inflammatory properties: Synthesis, biological evaluation and molecular modeling studies.

description: Small molecule binding data for protein Cyclooxygenase and Prostaglandin G/H synthase (cyclooxygenase), Uniprot P05979 and P35354
DOI: 10.7270/q28g8nb9
title: BindingDB Entry 50045118: Synthesis of new melatoninergic hexahydroindenopyridines.

description: Small molecule binding data for protein Melatonin receptor, Uniprot P48039 and P49286
DOI: 10.7270/q290257c
title: BindingDB Entry 50043442: TBA

description: Small molecule binding data for protein Cytochrome P450 2D6 (2D6), Uniprot P10635
DOI: 10.7270/q29025m9
title: BindingDB Entry 50046594: Synthesis of chiral ND-322, ND-364 and ND-364 derivatives as selective inhibitors of human gelatinase.

description: Small molecule binding data for protein Aminopeptidase N and Collagenase, Uniprot P08253, P14780, and P15145
DOI: 10.7270/q2cc12fv
title: BindingDB Entry 50046084: Synthesis and molecular docking of 1,2,3-triazole-based sulfonamides as aromatase inhibitors.

description: Small molecule binding data for protein Aromatase (CYP19), Uniprot P11511
DOI: 10.7270/q2dr2wz0
title: BindingDB Entry 50043441: TBA

description: Small molecule binding data for protein ADAM17, Disintegrin and metalloproteinase domain-containing protein 10 (ADAM10), and Matrix metalloproteinase-14 (MMP14), Uniprot O14672, P50281, and P78536
DOI: 10.7270/q2dr2x9w
title: BindingDB Entry 50046593: Rhododendrol glycosides as stereospecific tyrosinase inhibitors.

description: Small molecule binding data for protein Tyrosinase, Uniprot P14679
DOI: 10.7270/q2gq70bb
title: BindingDB Entry 50044590: Synthesis and biological evaluation of tetrahydro[1,4]diazepino[1,2-a]indol-1-ones as cyclin-dependent kinase inhibitors.

description: Small molecule binding data for protein Cyclin-Dependent Kinase 5 (CDK5), Uniprot Q00535 and Q15078
DOI: 10.7270/q2h41t56
title: BindingDB Entry 50046083: Development and validation of a novel assay to identify radiosensitizers that target nucleophosmin 1.

description: Small molecule binding data for protein NPM/ALK (Nucleophosmin/ALK tyrosine kinase receptor), Uniprot P06748
DOI: 10.7270/q2hm5b49
title: BindingDB Entry 50045567: Design, synthesis and biological evaluation of new hybrid anticonvulsants derived from N-benzyl-2-(2,5-dioxopyrrolidin-1-yl)propanamide and 2-(2,5-dioxopyrrolidin-1-yl)butanamide derivatives.

description: Small molecule binding data for protein Cytochrome P450 3A, Uniprot P08684
DOI: 10.7270/q2jd4zmw
title: BindingDB Entry 50046592: Non-basic azolotriazinone MCHR1 antagonists for the treatment of obesity: An empirical brain-exposures-driven candidate selection for in vivo efficacy studies.

description: Small molecule binding data for protein GPR24, Melanin-concentrating hormone receptor, and Voltage-gated potassium channel, Uniprot Q12809 and Q99705
DOI: 10.7270/q2k35w5t
title: BindingDB Entry 50044092: Structure-activity relationship of celecoxib and rofecoxib for the membrane permeabilizing activity.

description: Small molecule binding data for protein Cyclooxygenase and Prostaglandin G/H synthase (cyclooxygenase), Uniprot P05979 and P35354
DOI: 10.7270/q2mp54w9
title: BindingDB Entry 50045123: GPR103 antagonists demonstrating anorexigenic activity in vivo: design and development of pyrrolo[2,3-c]pyridines that mimic the C-terminal Arg-Phe motif of QRFP26.

description: Small molecule binding data for protein Cytochrome P450 2D6 (2D6), GPR103, Voltage-gated potassium channel, Voltage-gated potassium channel beta subunit Mink, and Voltage-gated sodium channel subunit Nav1.5, Uniprot P10635, P15382, Q12809, Q14524, and Q96P65
DOI: 10.7270/q2nc62vm
title: BindingDB Entry 50045566: 2-(Isopropylamino)thieno[3,2-d]pyrimidin-4(3H)-one derivatives as selective phosphodiesterase 7 inhibitors with potent in vivo efficacy.

description: Small molecule binding data for protein Phosphodiesterase 3 (PDE3), Phosphodiesterase 7, cAMP-specific 3',5'-cyclic phosphodiesterase 4B, and cGMP-specific 3',5'-cyclic phosphodiesterase, Uniprot O76074, Q07343, Q13946, and Q14432
DOI: 10.7270/q2p84dbj
title: BindingDB Entry 50043439: Influences of hydrocarbon linkers on the receptor binding affinities of gonadotropin-releasing hormone peptides.

description: Small molecule binding data for protein Gonadotropin releasing hormone 1 (GnRHR1), Uniprot P30968
DOI: 10.7270/q2pv6mwt
title: BindingDB Entry 50044091: Arylamino bisphosphonates: potent and selective inhibitors of the tumor-associated carbonic anhydrase XII.

description: Small molecule binding data for protein Carbonic Anhydrase XIV, Carbonic anhydrase, Carbonic anhydrase 12, Carbonic anhydrase 2, and Carbonic anhydrase 9, Uniprot O43570, P00915, P00918, Q16790, and Q9ULX7
DOI: 10.7270/q2r49sfk
title: BindingDB Entry 50045573: Application of cultured human mast cells (CHMC) for the design and structure-activity relationship of IgE-mediated mast cell activation inhibitors.

description: Small molecule binding data for protein Tyrosine-protein kinase SYK, Uniprot P43405
DOI: 10.7270/q2rf5wn3
title: BindingDB Entry 50045122: Coumarin hybrids as novel therapeutic agents.

description: Small molecule binding data for protein Acetylcholinesterase, Cholinesterase, and VEGF-receptor 2 and tyrosine-protein kinase SRC, Uniprot P06276, P12931, and P22303
DOI: 10.7270/q2tm7cn0
title: BindingDB Entry 50044090: Discovery of 4-anilinoa-carbolines as novel Brk inhibitors.

description: Small molecule binding data for protein AKT/p21CIP1, ALK tyrosine kinase receptor, CaM kinase IV, Glycogen synthase kinase-3, Homeodomain-interacting protein kinase 1, Homeodomain-interacting protein kinase 2 (HIPK2), Homeodomain-interacting protein kinase 3, JAK3/JAK1, MAP kinase ERK2, MAP kinase-activated protein kinase 3, MAP kinase-activated protein kinase 5, Mitogen-activated protein kinase 10, Mitogen-activated protein kinase 3, Myotonin-protein kinase, PAK1, Serine/threonine-protein kinase 24, Serine/threonine-protein kinase AKT, Serine/threonine-protein kinase MARK1, Serine/threonine-protein kinase MST4, Serine/threonine-protein kinase Nek1, Serine/threonine-protein kinase Nek2, Serine/threonine-protein kinase PIM, Serine/threonine-protein kinase VRK1, Serine/threonine-protein kinase c-TAK1, Tyrosine-protein kinase BRK, VEGF-receptor 2 and tyrosine-protein kinase SRC, c-Jun N-terminal kinase, JNK, p21-Activated kinase 2 (PAK2), and p21-Activated kinase 3 (PAK3), Uniprot O75914, P12931, P27361, P27448, P28482, P31749, P31751, P45983, P49841, P51955, P52333, P53779, Q09013, Q13153, Q13177, Q13882, Q16566, Q16644, Q86Z02, Q8IW41, Q96PY6, Q99986, Q9H2X6, Q9H422, Q9P0L2, Q9P1W9, Q9P289, Q9UM73, Q9Y243, and Q9Y6E0
DOI: 10.7270/q2v126db
title: BindingDB Entry 50044595: 2-Amino-7-substituted benzoxazole analogs as potent RSK2 inhibitors.

description: Small molecule binding data for protein Ribosomal protein S6 kinase alpha 3, Serine/threonine-protein kinase Aurora, and Tyrosine-protein kinase JAK2, Uniprot O14965, O60674, and P51812
DOI: 10.7270/q2w66nd8
title: BindingDB Entry 50045121: Novel pyrazoline derivatives as bi-inhibitor of COX-2 and B-Raf in treating cervical carcinoma.

description: Small molecule binding data for protein Cyclooxygenase and Cyclooxygenase-1 (COX-1), Uniprot P23219 and P35354
DOI: 10.7270/q2wq05km
title: BindingDB Entry 50046597: Nitrogenated honokiol derivatives allosterically modulate GABAA receptors and act as strong partial agonists.

description: Small molecule binding data for protein GABA receptor alpha-1/beta-2/gamma-2 subunit, Uniprot P14867, P18507, and P47870
DOI: 10.7270/q2zc84cq
title: BindingDB Entry 50044089: Discovery of a potent and selectivea3ß4 nicotinic acetylcholine receptor antagonist from ana-conotoxin synthetic combinatorial library.

description: Small molecule binding data for protein Neuronal acetylcholine receptor protein alpha-3/beta-4 subunit and Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit, Uniprot P04757, P09483, P12390, P12392, P30926, and P32297
DOI: 10.7270/q2zs2z3x
title: BindingDB Entry 50044594: Discovery and development of Janus kinase (JAK) inhibitors for inflammatory diseases.

description: Small molecule binding data for protein JAK2/TYK2, JAK3/JAK1, Tyrosine-protein kinase JAK1, Tyrosine-protein kinase JAK2, and Tyrosine-protein kinase JAK3, Uniprot O60674, P23458, P29597, P52333, and Q62137
DOI: 10.7270/q20003q8
title: BindingDB Entry 50045128: Flow synthesis and biological activity of aryl sulfonamides as selective carbonic anhydrase IX and XII inhibitors.

description: Small molecule binding data for protein Carbonic anhydrase, Carbonic anhydrase 12, Carbonic anhydrase 2, and Carbonic anhydrase 9, Uniprot O43570, P00915, P00918, and Q16790
DOI: 10.7270/q2028t8v
title: BindingDB Entry 50046087: Synthetic 1,2,3-triazole-linked glycoconjugates bind with high affinity to human galectin-3.

description: Small molecule binding data for protein Galectin-3, Uniprot P17931
DOI: 10.7270/q20g3mzk
title: BindingDB Entry 50046604: Functional Profiling of 2-Aminopyrimidine Histamine H4 Receptor Modulators.

description: Small molecule binding data for protein Histamine H1 receptor, Histamine H2 receptor, Histamine H4 Receptor, Histamine H4 receptor, Histamine receptor (H3), and Histamine receptor (H4), Uniprot P25021, P35367, Q91ZY1, Q91ZY2, Q9H3N8, and Q9Y5N1
DOI: 10.7270/q21g0npk
title: BindingDB Entry 50043444: TBA

description: Small molecule binding data for protein Glutamate carboxypeptidase II, Uniprot Q04609
DOI: 10.7270/q2251kpb
title: BindingDB Entry 50044096: Discovery of a potent and dissociated non-steroidal glucocorticoid receptor agonist containing an alkyl carbinol pharmacophore.

description: Small molecule binding data for protein Glucocorticoid receptor, Mineralocorticoid receptor (MR), and Progesterone receptor, Uniprot P04150, P06401, and P08235
DOI: 10.7270/q22j6dft
title: BindingDB Entry 50044601: Discovery of TD-4306, a long-actingß2-agonist for the treatment of asthma and COPD.

description: Small molecule binding data for protein Beta-1 adrenergic receptor, Beta-2 adrenergic receptor and beta-3 adrenergic receptor, and Beta-3 adrenergic receptor, Uniprot P07550, P08588, and P13945
DOI: 10.7270/q23r0vh6
title: BindingDB Entry 50045127: Discovery and structure-activity relationships of phenyl benzenesulfonylhydrazides as novel indoleamine 2,3-dioxygenase inhibitors.

description: Small molecule binding data for protein Indoleamine 2,3-dioxygenase, Uniprot P14902
DOI: 10.7270/q25t3n1w
title: BindingDB Entry 50044095: Pharmacophoric modifications lead to superpotentavß3 integrin ligands with suppresseda5ß1 activity.

description: Small molecule binding data for protein Fibronectin receptor beta/Integrin alpha5, Integrin alpha-IIb/beta-3, Integrin beta-3/Vitronectin receptor alpha, Integrin beta-5/Vitronectin receptor alpha, and Integrin beta-6/Vitronectin receptor alpha, Uniprot P05106, P05556, P06756, P08514, P08648, P18084, and P18564
DOI: 10.7270/q2668frt
title: BindingDB Entry 50044600: Discovery of a 4-aryloxy-1H-pyrrolo[3,2-c]pyridine and a 1-aryloxyisoquinoline series of TRPA1 antagonists.

description: Small molecule binding data for protein Cytochrome P450 1A, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), Cytochrome P450 3A, Transient receptor potential cation channel subfamily A member 1, and Transient receptor potential cation channel subfamily V member 1, Uniprot O75762, P05177, P08684, P10635, P11712, P33261, Q6RI86, and Q8NER1
DOI: 10.7270/q2765h1d
title: BindingDB Entry 50045577: The design, synthesis and biological evaluation of conformationally restricted 4-substituted-2,6-dimethylfuro[2,3-d]pyrimidines as multi-targeted receptor tyrosine kinase and microtubule inhibitors as potential antitumor agents.

description: Small molecule binding data for protein Epidermal growth factor receptor, Platelet-derived growth factor receptor beta, Similar to alpha-tubulin isoform 1, and Vascular endothelial growth factor receptor 2, Uniprot P00533, P09619, and P35968
DOI: 10.7270/q27h1m7x
title: BindingDB Entry 50045126: Strategies for the modulation of phase II metabolism in a series of PKCe inhibitors.

description: Small molecule binding data for protein Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), Cytochrome P450 3A, and Protein kinase C, epsilon, Uniprot P08684, P10635, P11712, and Q02156
DOI: 10.7270/q2805413
title: BindingDB Entry 50043450: The lignan (-)-hinokinin displays modulatory effects on human monoamine and GABA transporter activities.

description: Small molecule binding data for protein Excitatory Amino Acid EAAT2, Excitatory amino acid transporter 1, Excitatory amino acid transporter 3, GABA transporter 1, GABA transporter 3, and Glycine transporter 1, Uniprot P30531, P43003, P43004, P43005, P48066, and P48067
DOI: 10.7270/q28054fg
title: BindingDB Entry 50046602: Discovery of a novel Kv7 channel opener as a treatment for epilepsy.

description: Small molecule binding data for protein KCNQ (Kv7) potassium channel, Potassium voltage-gated channel subfamily KQT member 4, Voltage-gated potassium channel beta subunit Mink/subunit Kv7.1, and Voltage-gated potassium channel subunit Kv7.2/Kv7.3, Uniprot O43525, O43526, P15382, P51787, P56696, and Q9JK96
DOI: 10.7270/q29k4cr6
title: BindingDB Entry 50044094: Non-imidazole histamine H3 receptor ligands incorporating antiepileptic moieties.

description: Small molecule binding data for protein Histamine H1 receptor, Histamine receptor (H3), and Histamine receptor (H4), Uniprot P35367, Q9H3N8, and Q9Y5N1
DOI: 10.7270/q29z96fs
title: BindingDB Entry 50044599: Structure-activity relationships of privileged structures lead to the discovery of novel biased ligands at the dopamine D2 receptor.

description: Small molecule binding data for protein Dopamine receptor D2L/neurotensin receptor NTS1, Uniprot P14416
DOI: 10.7270/q2bc419g
title: BindingDB Entry 50046092: 9H-Carbazole-1-carboxamides as potent and selective JAK2 inhibitors.

description: Small molecule binding data for protein JAK2/TYK2, JAK3/JAK1, Tyrosine-protein kinase JAK1, and Tyrosine-protein kinase JAK2, Uniprot O60674, P23458, P29597, and P52333
DOI: 10.7270/q2bz67rd
title: BindingDB Entry 50045576: The amide linker in nonpeptide neurotensin receptor ligands plays a key role in calcium signaling at the neurotensin receptor type 2.

description: Small molecule binding data for protein Neurotensin receptor 1 and Neurotensin receptor 2, Uniprot P20789 and Q63384
DOI: 10.7270/q2c82bxs
title: BindingDB Entry 50045125: Design and synthesis of 5-[(2-chloro-6-fluorophenyl)acetylamino]-3-(4-fluorophenyl)-4-(4-pyrimidinyl)isoxazole (AKP-001), a novel inhibitor of p38 MAP kinase with reduced side effects based on the antedrug concept.

description: Small molecule binding data for protein MAP kinase p38, Mitogen-activated protein kinase 10, Mitogen-activated protein kinase 14, and Mitogen-activated protein kinase 9, Uniprot P45984, P53779, Q15759, and Q16539
DOI: 10.7270/q2cr5vs5
title: BindingDB Entry 50043449: TBA

description: Small molecule binding data for protein X-linked inhibitor of apoptosis protein (XIAP), Uniprot P98170
DOI: 10.7270/q2cr5w6z
title: BindingDB Entry 50046601: Small cyclic agonists of iron regulatory hormone hepcidin.

description: Small molecule binding data for protein Solute carrier family 40 member 1, Uniprot Q9NP59
DOI: 10.7270/q2fb54fg
title: BindingDB Entry 50044093: Using 'biased-privileged' scaffolds to identify lysine methyltransferase inhibitors.

description: Small molecule binding data for protein Protein G9a (G9a) and SET domain-containing protein 7/9 (Set7/9), Uniprot Q8WTS6 and Q96KQ7
DOI: 10.7270/q2fq9z54
title: BindingDB Entry 50044598: Discovery of 5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine inhibitors of Erk2.

description: Small molecule binding data for protein Cyclin-dependent kinase 2 and MAP kinase ERK2, Uniprot P24941 and P28482
DOI: 10.7270/q2gq70fp
title: BindingDB Entry 50045575: Design and synthesis of potent, selective phenylimidazole-based FVIIa inhibitors.

description: Small molecule binding data for protein Coagulation factor VII, Coagulation factor X/antithrombin III, Prothrombin, and Trypsin, Uniprot P00734, P00742, P07477, P07478, P08709, and P35030
DOI: 10.7270/q2gx4d6f
title: BindingDB Entry 50045124: Pharmacological evaluation and docking studies ofa,ß-unsaturated carbonyl based synthetic compounds as inhibitors of secretory phospholipase A2, cyclooxygenases, lipoxygenase and proinflammatory cytokines.

description: Small molecule binding data for protein Cyclooxygenase, Lipoxygenase, and Prostaglandin G/H synthase (cyclooxygenase), Uniprot P05979 and P35354
DOI: 10.7270/q2hh6mhw
title: BindingDB Entry 50043448: Substrate-based fragment identification for the development of selective, nonpeptidic inhibitors of striatal-enriched protein tyrosine phosphatase.

description: Small molecule binding data for protein Mitogen-activated protein kinase phosphatase 5 (MKP5), Receptor-type tyrosine-protein phosphatase F (LAR), T-cell protein-tyrosine phosphatase, Tyrosine-Protein Phosphatase (CD45), and tyrosine-protein phosphatase non-receptor type 5 isoform a, Uniprot P08575, P10586, P17706, P54829, and Q9Y6W6
DOI: 10.7270/q2hh6mwt
title: BindingDB Entry 50046600: Pseudosaccharin amines as potent and selective KV1.5 blockers.

description: Small molecule binding data for protein Voltage-gated potassium channel subunit Kv1.5, Uniprot P22460
DOI: 10.7270/q2kh0pw0
title: BindingDB Entry 50044597: Discovery of biarylaminoquinazolines as novel tubulin polymerization inhibitors.

description: Small molecule binding data for protein Epidermal growth factor receptor, Fibroblast growth factor receptor 1, Tyrosine-protein kinase ABL1, and VEGF-receptor 2 and tyrosine-protein kinase SRC, Uniprot P00519, P00533, P11362, and P12931
DOI: 10.7270/q2kw5hs8
title: BindingDB Entry 50046090: Allobetulin derived seco-oleananedicarboxylates act as inhibitors of acetylcholinesterase.

description: Small molecule binding data for protein Acetylcholinesterase and Butyrylcholinesterase (BuChE), Uniprot O42275 and P81908
DOI: 10.7270/q2mc91q7
title: BindingDB Entry 50045574: Design and synthesis of novel 1,2-dithiolan-4-yl benzoate derivatives as PTP1B inhibitors.

description: Small molecule binding data for protein Protein tyrosine phosphatase SHP-2 (SHP-2), Protein-tyrosine phosphatase 1B, Protein-tyrosine phosphatase 1C, and T-cell protein-tyrosine phosphatase, Uniprot P17706, P18031, P29350, and Q06124
DOI: 10.7270/q2n58p5s
title: BindingDB Entry 50046599: Discovery of diazepane amide DORAs and 2-SORAs enabled by exploration of isosteric quinazoline replacements.

description: Small molecule binding data for protein Orexin receptor 2, Uniprot O43614 and S4X0W3
DOI: 10.7270/q2n87c7m
title: BindingDB Entry 50043447: Synthesis and bioconversions of formestane.

description: Small molecule binding data for protein Aromatase (CYP19), Uniprot P11511
DOI: 10.7270/q2q81fn5
title: BindingDB Entry 50044596: Application of encoded library technology (ELT) to a protein-protein interaction target: discovery of a potent class of integrin lymphocyte function-associated antigen 1 (LFA-1) antagonists.

description: Small molecule binding data for protein Integrin alpha-L/beta-2 (LFA-1), Uniprot P20701
DOI: 10.7270/q2qj7k1s
title: BindingDB Entry 50046089: Design of selective PI3Ka inhibitors starting from a promiscuous pan kinase scaffold.

description: Small molecule binding data for protein PI3-kinase subunit alpha, PI3-kinase subunit beta, PI3-kinase subunit delta, PI3-kinase subunit gamma, Serine/threonine-protein kinase mTOR, and Vascular endothelial growth factor receptor 2, Uniprot O00329, P35968, P42336, P42338, P42345, and P48736
DOI: 10.7270/q2rx9dvb
title: BindingDB Entry 50046598: Design, synthesis and structure-activity relationship studies of novel phenoxyacetamide-based free fatty acid receptor 1 agonists for the treatment of type 2 diabetes.

description: Small molecule binding data for protein Free fatty acid receptor 1, Uniprot O14842