cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.14006200
title: Real-life association between inhaler technique, patient preference and asthma control in patients with uncontrolled asthma switched to budesonide/formoterol DuoResp® Spiromax® combination

description: <b>Objective:</b> In asthma, treatment effectiveness is strongly influenced by the quality of inhaler use. New devices such as Spiromax® have been specifically developed to improve ease of use. It is crucial to determine whether switching to such a device improves inhaler technique and clinical outcomes, and to identify factors associated with handling errors. <b>Methods:</b> This observational study assessed inhaler device handling errors in 1435 asthma patients recruited via 135 participating physicians in France, before and after switching therapy from the Symbicort Turbuhaler® or Seretide® Diskus® to DuoResp® Spiromax®. Patients received training in the use of their new device at baseline and were re-assessed after three months. <b>Results:</b> After three months of use, 67% of patients were using the DuoResp® Spiromax® with no handling errors, and 88% with no critical errors. The presence of comorbidities was associated with handling errors overall. Concurrent illness potentially affecting device handling and previous training were associated with critical device handling errors. Most patients (85.4%) preferred DuoResp® Spiromax® over their previous device. Levels of inadequately controlled or uncontrolled asthma were reduced from baseline among patients using DuoResp® Spiromax® (8.6% versus 64.6%), and were higher in patients with critical handling errors. <b>Conclusions:</b> Effective patient education, correct inhaler technique, treatment adherence and devices associated with high patient satisfaction are interrelated factors key to the successful delivery of inhaled asthma therapy. Inhaler technique and patient device satisfaction should be routinely assessed in treated patients with uncontrolled asthma. Supplemental data for this article can be accessed at publisher’s website.
DOI: 10.6084/m9.figshare.13637255.v1
title: Cleaning agent usage in healthcare professionals and relationship to lung and skin symptoms

description: Healthcare workers have an increased risk of respiratory symptoms and dermatitis, likely related to cleaning/disinfecting agents. The aim of this study was to identify work tasks and cleaning/disinfecting agents associated with respiratory symptoms and hand dermatitis among healthcare workers in a tertiary hospital. Cleaning agent usage, respiratory symptoms and skin symptoms were recorded by participants using a questionnaire in a cross-sectional study. Age and sex adjusted odds ratios (OR) were used to examine associations between job tasks, exposures, respiratory, and skin outcomes. Two hundred and thirty healthcare workers who were exposed to cleaning agents were compared with 77 who had no, or minimal, exposure. Exposed workers had an increased risk of respiratory symptoms (adjusted OR = 2.17; 95% CI: 1.18–4.14) and skin symptoms (adjusted OR = 1.77; 95% CI: 1.00 − 3.17). Washing instruments manually, using aerosol products, cleaning operating rooms, cleaning sanitary rooms, preparing disinfectants, and filling devices with cleaning products were cleaning tasks associated with various respiratory symptoms. Bleach was the only cleaning agent associated with a respiratory symptom: tightness in the chest (unadjusted OR = 2.46; 95% CI: 1.01–6.89) but statistical significance did not persist after adjustment for age and sex. Hand dermatitis was associated with actual disinfecting tasks (adjusted OR = 2.19; 95% CI: 1.10–4.66). Bleach was the only cleaning agent significantly associated with hand dermatitis (adjusted OR = 2.54; 95% CI: 1.32–5.13). This study provides insight into possible work tasks that need interventions to reduce or prevent respiratory and skin symptoms in healthcare workers.
DOI: 10.6084/m9.figshare.14006200.v2
title: Real-life association between inhaler technique, patient preference and asthma control in patients with uncontrolled asthma switched to budesonide/formoterol DuoResp® Spiromax® combination

description: <b>Objective:</b> In asthma, treatment effectiveness is strongly influenced by the quality of inhaler use. New devices such as Spiromax® have been specifically developed to improve ease of use. It is crucial to determine whether switching to such a device improves inhaler technique and clinical outcomes, and to identify factors associated with handling errors. <b>Methods:</b> This observational study assessed inhaler device handling errors in 1435 asthma patients recruited via 135 participating physicians in France, before and after switching therapy from the Symbicort Turbuhaler® or Seretide® Diskus® to DuoResp® Spiromax®. Patients received training in the use of their new device at baseline and were re-assessed after three months. <b>Results:</b> After three months of use, 67% of patients were using the DuoResp® Spiromax® with no handling errors, and 88% with no critical errors. The presence of comorbidities was associated with handling errors overall. Concurrent illness potentially affecting device handling and previous training were associated with critical device handling errors. Most patients (85.4%) preferred DuoResp® Spiromax® over their previous device. Levels of inadequately controlled or uncontrolled asthma were reduced from baseline among patients using DuoResp® Spiromax® (8.6% versus 64.6%), and were higher in patients with critical handling errors. <b>Conclusions:</b> Effective patient education, correct inhaler technique, treatment adherence and devices associated with high patient satisfaction are interrelated factors key to the successful delivery of inhaled asthma therapy. Inhaler technique and patient device satisfaction should be routinely assessed in treated patients with uncontrolled asthma. Supplemental data for this article can be accessed at publisher’s website.
DOI: 10.6084/m9.figshare.13615840.v1
title: Extent of non-adherence and non-persistence in asthma patients: analysis of a large claims data set

description: The objective of this study was to assess non-adherence (NA) and non-persistence (NP) to long-acting asthma medications in Germany by differentiating between measurement of NA in periods of therapy continuation and measurement of NP in therapy-naïve patients. We analyzed treatment adherence to long-acting asthma medication using German claims data for periods of treatment continuation based on the medication possession ratio (MPR) and the proportion of days covered. Persistence was assessed in treatment-naïve patients. Outcomes were observed from the date of the first to the last prescription within a 12-month period. Both NA and NP analyses considered prescription supply, using either defined daily dosages, or prescribed daily dosages derived from a medical chart review. We identified 52,508 asthma patients (mean age: 40.1, 58.4% female) who received at least two long-acting asthma prescriptions within 12 months; 50,660 treatment-naïve patients were included in the NP analysis (mean age: 39.7, 58.8% female). The mean 12-month MPR was 38.5% (89.4% NA according to MPR ≤ 80%) and the average proportion of days covered was 40.4% (85.9% NA). Agent-specific MPR and NA rates varied between 31.8% (91.8% NA) and 56.2% (71.6% NA). The average weighted-MPR increased to 53.1% when using the prescribed daily dosage. Based on <i>a</i> &gt; 90-day gap definition, 86.7% of patients were considered non-persistent after 12 months (&gt;180: 72.3%). When using prescribed daily dosages, NP rates ranged from 66.7 to 78.5%. High levels of treatment NA and NP indicate a substantial need to improve adherence and persistence to long-acting asthma medication in Germany.
DOI: 10.6084/m9.figshare.19703536
title: Supplementary Material for: Effect of Germline MEFV polymorphisms on the prognosis of Japanese children with cancer: A regional analysis

description: Introduction: MEFV is the gene responsible for familial Mediterranean fever (FMF). It encodes pyrin, which controls inflammation; Besides, previous studies have reported that some germline MEFV variants were associated with tumour susceptibility. Materials and Methods: The loci of 12 germline MEFV variants were genotyped in 153 Japanese children with cancer, and the frequencies of these variants among the patient groups were compared with those in the general Japanese population. Additionally, the relationship between these variants and clinical data, including relapse and death, was investigated. Results: Minor allele frequencies did not differ between patients and the general population, or between sex, age at diagnosis, and diagnosis among patients. P369S/R408Q associated with significantly lower relapse-free survival in all patient analyses and in patients with solid tumours. Additionally, although the results were not significant, E148Q/L110P was likely to associate with worse relapse-free survival in patients with solid tumours. Discussion/Conclusion: Despite several limitations, this study provided the novel insight that the germline MEFV variants are associated with the clinical outcome of paediatric cancer.
DOI: 10.6084/m9.figshare.19703536.v1
title: Supplementary Material for: Effect of Germline MEFV polymorphisms on the prognosis of Japanese children with cancer: A regional analysis

description: Introduction: MEFV is the gene responsible for familial Mediterranean fever (FMF). It encodes pyrin, which controls inflammation; Besides, previous studies have reported that some germline MEFV variants were associated with tumour susceptibility. Materials and Methods: The loci of 12 germline MEFV variants were genotyped in 153 Japanese children with cancer, and the frequencies of these variants among the patient groups were compared with those in the general Japanese population. Additionally, the relationship between these variants and clinical data, including relapse and death, was investigated. Results: Minor allele frequencies did not differ between patients and the general population, or between sex, age at diagnosis, and diagnosis among patients. P369S/R408Q associated with significantly lower relapse-free survival in all patient analyses and in patients with solid tumours. Additionally, although the results were not significant, E148Q/L110P was likely to associate with worse relapse-free survival in patients with solid tumours. Discussion/Conclusion: Despite several limitations, this study provided the novel insight that the germline MEFV variants are associated with the clinical outcome of paediatric cancer.
DOI: 10.48370/ofd/msk8uu
title: Lyomyces crustosus (Pers.) P.Karst., 5027

description: Fungarium Macromycetes
DOI: 10.6084/m9.figshare.19703182.v1
title: Dataset for "Complex interplay between organic and secondary inorganic aerosols with ambient relative humidity implicates the aerosol liquid water content over India during wintertime"

description: Amar Krishna Gopinath, Subha S. Raj, Snehitha M. Kommula, Christi Jose, Upasana Panda, Yukti Bishambu, Narendra Ojha, R. Ravikrishna, Pengfei Liu, Sachin S. Gunthe <br> Dataset for "Complex interplay between organic and secondary inorganic aerosols with ambient relative humidity implicates the aerosol liquid water content over India during wintertime"
DOI: 10.6084/m9.figshare.19661399
title: Survival data from An experimental test of Lanchester's models of combat in the neotropical termite <i>Nasutitermes corniger</i> (Blattodea: Termitidae)

description: This is a CSV document containing the data used for the survival GLMM analysis.
DOI: 10.6084/m9.figshare.19661399.v1
title: Survival data from An experimental test of Lanchester's models of combat in the neotropical termite <i>Nasutitermes corniger</i> (Blattodea: Termitidae)

description: This is a CSV document containing the data used for the survival GLMM analysis.
DOI: 10.6084/m9.figshare.19661402
title: Battle data from An experimental test of Lanchester's models of combat in the neotropical termite <i>Nasutitermes corniger</i> (Blattodea: Termitidae)

description: This is a .txt with battle death information.
DOI: 10.6084/m9.figshare.19661402.v1
title: Battle data from An experimental test of Lanchester's models of combat in the neotropical termite <i>Nasutitermes corniger</i> (Blattodea: Termitidae)

description: This is a .txt with battle death information.
DOI: 10.6084/m9.figshare.19661408
title: R code on Bayesian output from An experimental test of Lanchester's models of combat in the neotropical termite <i>Nasutitermes corniger</i> (Blattodea: Termitidae)

description: This is an Rmarkdown files containing the code used to summarize output from the Bayesian analysis.
DOI: 10.6084/m9.figshare.19661414
title: Behavioral data from An experimental test of Lanchester's models of combat in the neotropical termite <i>Nasutitermes corniger</i> (Blattodea: Termitidae)

description: This is a CSV document containing the data used for the behavioral analysis.
DOI: 10.6084/m9.figshare.19661408.v1
title: R code on Bayesian output from An experimental test of Lanchester's models of combat in the neotropical termite <i>Nasutitermes corniger</i> (Blattodea: Termitidae)

description: This is an Rmarkdown files containing the code used to summarize output from the Bayesian analysis.
DOI: 10.6084/m9.figshare.19661414.v1
title: Behavioral data from An experimental test of Lanchester's models of combat in the neotropical termite <i>Nasutitermes corniger</i> (Blattodea: Termitidae)

description: This is a CSV document containing the data used for the behavioral analysis.
DOI: 10.6084/m9.figshare.19661417
title: GLMM R code on survival from An experimental test of Lanchester's models of combat in the neotropical termite <i>Nasutitermes corniger</i> (Blattodea: Termitidae)

description: This is an Rmarkdown document detailing the code used for the binomial GLMM on survival rates.
DOI: 10.6084/m9.figshare.19661417.v1
title: GLMM R code on survival from An experimental test of Lanchester's models of combat in the neotropical termite <i>Nasutitermes corniger</i> (Blattodea: Termitidae)

description: This is an Rmarkdown document detailing the code used for the binomial GLMM on survival rates.
DOI: 10.6084/m9.figshare.19661420.v1
title: Configuration file; from An experimental test of Lanchester's models of combat in the neotropical termite <i>Nasutitermes corniger</i> (Blattodea: Termitidae)

description: This file is an example of our .conf file used to run the Bayesian analyses.
DOI: 10.6084/m9.figshare.19661423.v1
title: GLMM R code on behavioral data from An experimental test of Lanchester's models of combat in the neotropical termite <i>Nasutitermes corniger</i> (Blattodea: Termitidae)

description: This is an Rmarkdown document detailing the code used for the binomial GLMM on behavioral data.
DOI: 10.6084/m9.figshare.19661423
title: GLMM R code on behavioral data from An experimental test of Lanchester's models of combat in the neotropical termite <i>Nasutitermes corniger</i> (Blattodea: Termitidae)

description: This is an Rmarkdown document detailing the code used for the binomial GLMM on behavioral data.
DOI: 10.6084/m9.figshare.19661420
title: Configuration file; from An experimental test of Lanchester's models of combat in the neotropical termite <i>Nasutitermes corniger</i> (Blattodea: Termitidae)

description: This file is an example of our .conf file used to run the Bayesian analyses.
DOI: 10.48370/ofd/gooxau
title: Lyomyces crustosus (Pers.) P.Karst., 5219

description: Fungarium Macromycetes
DOI: 10.48370/ofd/0b2p0f/coemaj
title: MRIPAS_coll_164063_BisonBonasus_1996_scan.jpg

description: :unav
DOI: 10.48370/ofd/0b2p0f/thvzkk
title: MRIPAS_coll_164063_BisonBonasus_1996_M_ad_skull_without_horns_scan3D.rar

description: skull without horns
DOI: 10.48370/ofd/0b2p0f/ow6cuj
title: MRIPAS_coll_164063_BisonBonasus_1996_M_ad_skull_with_horns_scan3D.rar

description: skull with horns
DOI: 10.48370/ofd/0b2p0f/xrjvyd
title: MRIPAS_coll_164063_BisonBonasus_1996_M_ad_jaw_scan3D.stl

description: jaw
DOI: 10.48370/ofd/0b2p0f/ncmqik
title: MRIPAS_coll_164063_BisonBonasus_1996_M_ad_skull_with_horns_scan3D_small.stl

description: skull with horns
DOI: 10.48370/ofd/0b2p0f/ioj0xd
title: MRIPAS_coll_164063_BisonBonasus_1996_M_ad_skull_without_horns_scan3D_small.stl

description: skull without horns
DOI: 10.48370/ofd/0b2p0f
title: Bison bonasus - 164063, Zoological collection of the Mammal Research Institute, PAS

description: Bison bonasus (European bison) from Zoological collection of the Mammal Research Institute, PAS. Collected 1996-03-13 in: Białowieża Forest, Poland. Material type: skull, jaw
DOI: 10.6084/m9.figshare.19635515
title: Supplementary Table S1 from Radial porosity profiles: a new bone histological method for comparative developmental analysis of diametric limb bone growth

description: Details of the sampled bones along with their porosity measurements to define their radial porosity profiles (RPPs).
DOI: 10.6084/m9.figshare.19635515.v2
title: Supplementary Table S1 from Radial porosity profiles: a new bone histological method for comparative developmental analysis of diametric limb bone growth

description: Details of the sampled bones along with their porosity measurements to define their radial porosity profiles (RPPs).
DOI: 10.6084/m9.figshare.19635524
title: Supplementary Table S3 from Radial porosity profiles: a new bone histological method for comparative developmental analysis of diametric limb bone growth

description: Group memberships of elements in the duck dataset, including incomplete RPPs, and their congruence between DTW-hclust and ED-hclust analysed in the 4-group setup.
DOI: 10.6084/m9.figshare.19635521
title: Supplementary Information 4 from Radial porosity profiles: a new bone histological method for comparative developmental analysis of diametric limb bone growth

description: R output of the results of the analyses of the duck-only dataset
DOI: 10.6084/m9.figshare.19635524.v1
title: Supplementary Table S3 from Radial porosity profiles: a new bone histological method for comparative developmental analysis of diametric limb bone growth

description: Group memberships of elements in the duck dataset, including incomplete RPPs, and their congruence between DTW-hclust and ED-hclust analysed in the 4-group setup.
DOI: 10.6084/m9.figshare.19635530
title: Supplementary Table S4 from Radial porosity profiles: a new bone histological method for comparative developmental analysis of diametric limb bone growth

description: Group memberships of elements in the complete dataset, including incomplete RPPs, and their congruence between DTW-hclust and ED-hclust analysed in the 5-group setup.
DOI: 10.6084/m9.figshare.19635530.v2
title: Supplementary Table S4 from Radial porosity profiles: a new bone histological method for comparative developmental analysis of diametric limb bone growth

description: Group memberships of elements in the complete dataset, including incomplete RPPs, and their congruence between DTW-hclust and ED-hclust analysed in the 5-group setup.
DOI: 10.6084/m9.figshare.19635521.v1
title: Supplementary Information 4 from Radial porosity profiles: a new bone histological method for comparative developmental analysis of diametric limb bone growth

description: R output of the results of the analyses of the duck-only dataset
DOI: 10.6084/m9.figshare.19635533.v1
title: Supplementary Information 2 from Radial porosity profiles: a new bone histological method for comparative developmental analysis of diametric limb bone growth

description: R scripts of the different analyses performed in this study
DOI: 10.6084/m9.figshare.19635515.v1
title: Supplementary Table S1 from Radial porosity profiles: a new bone histological method for comparative developmental analysis of diametric limb bone growth

description: Details of the sampled bones along with their porosity measurements to define their radial porosity profiles (RPPs).
DOI: 10.6084/m9.figshare.19635533
title: Supplementary Information 2 from Radial porosity profiles: a new bone histological method for comparative developmental analysis of diametric limb bone growth

description: R scripts of the different analyses performed in this study
DOI: 10.6084/m9.figshare.19635539
title: Supplementary Information 6 from Radial porosity profiles: a new bone histological method for comparative developmental analysis of diametric limb bone growth

description: R output of the results of the analyses of the complete dataset
DOI: 10.6084/m9.figshare.19635539.v1
title: Supplementary Information 6 from Radial porosity profiles: a new bone histological method for comparative developmental analysis of diametric limb bone growth

description: R output of the results of the analyses of the complete dataset
DOI: 10.6084/m9.figshare.19635542
title: Supplementary Table S2 from Radial porosity profiles: a new bone histological method for comparative developmental analysis of diametric limb bone growth

description: Sorting of duckling limb elements by GBTM and K-means into two groups within early (4 & 8 dph), mid- (15 dph) and late (30 dph) juveniles
DOI: 10.6084/m9.figshare.19635542.v1
title: Supplementary Table S2 from Radial porosity profiles: a new bone histological method for comparative developmental analysis of diametric limb bone growth

description: Sorting of duckling limb elements by GBTM and K-means into two groups within early (4 & 8 dph), mid- (15 dph) and late (30 dph) juveniles
DOI: 10.6084/m9.figshare.19635530.v1
title: Supplementary Table S4 from Radial porosity profiles: a new bone histological method for comparative developmental analysis of diametric limb bone growth

description: Group memberships of elements in the complete dataset, including incomplete RPPs, and their congruence between DTW-hclust and ED-hclust analysed in the 5-group setup.
DOI: 10.6084/m9.figshare.19635554.v1
title: Supplementary Information 5 from Radial porosity profiles: a new bone histological method for comparative developmental analysis of diametric limb bone growth

description: R output of the results of the analyses of the extinct paravian dinosaur-only dataset
DOI: 10.6084/m9.figshare.19635554
title: Supplementary Information 5 from Radial porosity profiles: a new bone histological method for comparative developmental analysis of diametric limb bone growth

description: R output of the results of the analyses of the extinct paravian dinosaur-only dataset
DOI: 10.6084/m9.figshare.19635560
title: Supplementary Information 3 from Radial porosity profiles: a new bone histological method for comparative developmental analysis of diametric limb bone growth

description: R scripts of the different graphs used in data and results visualization in this study
DOI: 10.6084/m9.figshare.19635560.v1
title: Supplementary Information 3 from Radial porosity profiles: a new bone histological method for comparative developmental analysis of diametric limb bone growth

description: R scripts of the different graphs used in data and results visualization in this study
DOI: 10.48370/ofd/ve7aif/dynvkd
title: MRIPAS_coll_170662_BisonBonasus_2015_M_ad_skull_without_horns_scan3D.rar

description: skull without horns
DOI: 10.48370/ofd/ve7aif/ejawxe
title: MRIPAS_coll_170662_BisonBonasus_2015_M_ad_skull_with_horns_scan3D.rar

description: skull with horns
DOI: 10.48370/ofd/ve7aif/v32mqb
title: MRIPAS_coll_170662_BisonBonasus_2015_M_ad_jaw_scan3D.rar

description: jaw
DOI: 10.48370/ofd/ve7aif/nc3o1c
title: MRIPAS_coll_170662_BisonBonasus_2015_M_ad_jaw_scan3D_small.stl

description: jaw
DOI: 10.48370/ofd/ve7aif/5apfeg
title: MRIPAS_coll_170662_BisonBonasus_2015_M_ad_skull_with_horns_scan3D_small.stl

description: skull with horns
DOI: 10.48370/ofd/ve7aif/9aomom
title: MRIPAS_coll_170662_BisonBonasus_2015_M_ad_skull_without_horns_scan3D_small.stl

description: skull without horns
DOI: 10.48370/ofd/ve7aif
title: Bison bonasus - 170662, Zoological collection of the Mammal Research Institute, PAS

description: Bison bonasus (European bison) from Zoological collection of the Mammal Research Institute, PAS. Collected 2015-09-01 in: Białowieża National Park, European bison Show Reserve, Poland. Material type: skull, jaw