cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7732328.v1
title: Fig 3.jpg

description: Four figures and two tables. The dataset refers to creation and analysis of zebrafish carrying transgenes encoding human PTDSS1, as described in the F1000 manuscript, "<strong>Analysis of transgenic zebrafish expressing the Lenz-Majewski syndrome gene<i> PTDSS1</i> in skeletal cell lineages</strong>". The Excel spreadsheets give raw qPCR(relating to Figure 2) and phenotyping (relating to Figure 4) data.
DOI: 10.6084/m9.figshare.7732265
title: Expert judgement policy (with code book)

description: The data details the experts judgement policy for which the medical students were compared to. The codebook explains the variables.
DOI: 10.6084/m9.figshare.7732268
title: Failure dataset

description: This failure dataset contains the injected faults, the workload, the effects of failure (both the user-side impact and our own in-depth correctness checks), and the error logs produced by the OpenStack cloud management system.<br>Please refers to the paper "How Bad Can a Bug Get? Empirical analysis of software failures in the OpenStack cloud computing platform" (ESEC/FSE '19).<br>Please, cite the following paper if you use the dataset:<br><pre>@inproceedings{cotroneo2019bad,</pre><pre>title={How bad can a bug get? an empirical analysis of software failures in the OpenStack cloud computing platform},</pre><pre>author={Cotroneo, Domenico and De Simone, Luigi and Liguori, Pietro and Natella, Roberto and Bidokhti, Nematollah},</pre><pre>booktitle={Proceedings of the 2019 27th ACM Joint Meeting on European Software Engineering Conference and Symposium on the Foundations of Software Engineering},</pre><pre>pages={200--211},</pre><pre>year={2019} }</pre><pre><br></pre><pre>Visit the github repo for any updates: https://github.com/dessertlab/Fault-Injection-Dataset</pre>
DOI: 10.7284/127375
title: Gravimeter data collected during research cruise AR22 using a Bell BGM-3 instrument system onboard the platform RV Neil Armstrong

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7732328.v3
title: Analysis of transgenic zebrafish expressing the Lenz-Majewski syndrome gene PTDSS1 in skeletal cell lineages.

description: Four figures and two tables. The dataset refers to creation and analysis of zebrafish carrying transgenes encoding human PTDSS1, as described in the F1000 manuscript, "<strong>Analysis of transgenic zebrafish expressing the Lenz-Majewski syndrome gene<i> PTDSS1</i> in skeletal cell lineages</strong>". The Excel spreadsheets give raw qPCR(relating to Figure 2) and phenotyping (relating to Figure 4) data.
DOI: 10.6084/m9.figshare.7732265.v1
title: Expert judgement policy (with code book)

description: The data details the experts judgement policy for which the medical students were compared to. The codebook explains the variables.
DOI: 10.7284/127364
title: Gyrocompass data collected during research cruise AR22 using a Sperry NAVIGAT X MK 1 instrument system onboard the platform RV Neil Armstrong

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7732259
title: Developing sport expertise in youth sport: A decision training program in basketball

description: <b>Background:</b> The purpose of the study was to examine the effect of applying a decision training program, using a tool combination of video feedback and questioning, on the development of decision-making, execution skills and procedural knowledge in basketball players. <b>Methods:</b> A three phase quasi-experimental design was implemented: Phase A (pre-test), Phase B (post-test) and Phase C (re-test). The sample was comprised of twelve male players aged between 12 and 13 years old, included in the Under-14 category, who were divided into two groups: experimental group (n=5) and control group (n=6). The independent variable of the study was the decision training program that was applied over 11 weeks. Players had to analyze the causes and reasons of the decision made, through video feedback and questioning. Decision-making and skill execution variables were assessed using the French & Thomas (1987) observation instrument, while a validated questionnaire was used to assess procedural knowledge in basketball. <b>Results:</b>The results reported that sport expertise improved in players from the experimental group, who showed a significantly higher mean percentage of successful decisions and execution skills than the control group in post-test time. In the intra-group analysis, the experimental group significantly improved in terms of some of the variables of decision-making, execution skills and procedural knowledge from the pre-test to the post-test. <b>Discussion:</b>These results reinforce the idea of including cognitive tools in training, such as video-feedback and questioning to improve sport expertise in athletes' formative stages and presumably to improve their performance but maintaining decision training throughout time<b>.</b> <b> </b>
DOI: 10.6084/m9.figshare.7732328.v2
title: Analysis of transgenic zebrafish expressing the Lenz-Majewski syndrome gene PTDSS1 in skeletal cell lineages.

description: Four figures and two tables. The dataset refers to creation and analysis of zebrafish carrying transgenes encoding human PTDSS1, as described in the F1000 manuscript, "<strong>Analysis of transgenic zebrafish expressing the Lenz-Majewski syndrome gene<i> PTDSS1</i> in skeletal cell lineages</strong>". The Excel spreadsheets give raw qPCR(relating to Figure 2) and phenotyping (relating to Figure 4) data.
DOI: 10.6084/m9.figshare.7732244
title: Baseline and primary data (including code book)

description: This data contains the baseline and primary data points for the medical students who participated in the ORaClES study. The codebook describes the variables.
DOI: 10.6084/m9.figshare.7732259.v1
title: Developing sport expertise in youth sport: A decision training program in basketball

description: <b>Background:</b> The purpose of the study was to examine the effect of applying a decision training program, using a tool combination of video feedback and questioning, on the development of decision-making, execution skills and procedural knowledge in basketball players. <b>Methods:</b> A three phase quasi-experimental design was implemented: Phase A (pre-test), Phase B (post-test) and Phase C (re-test). The sample was comprised of twelve male players aged between 12 and 13 years old, included in the Under-14 category, who were divided into two groups: experimental group (n=5) and control group (n=6). The independent variable of the study was the decision training program that was applied over 11 weeks. Players had to analyze the causes and reasons of the decision made, through video feedback and questioning. Decision-making and skill execution variables were assessed using the French & Thomas (1987) observation instrument, while a validated questionnaire was used to assess procedural knowledge in basketball. <b>Results:</b>The results reported that sport expertise improved in players from the experimental group, who showed a significantly higher mean percentage of successful decisions and execution skills than the control group in post-test time. In the intra-group analysis, the experimental group significantly improved in terms of some of the variables of decision-making, execution skills and procedural knowledge from the pre-test to the post-test. <b>Discussion:</b>These results reinforce the idea of including cognitive tools in training, such as video-feedback and questioning to improve sport expertise in athletes' formative stages and presumably to improve their performance but maintaining decision training throughout time<b>.</b> <b> </b>
DOI: 10.7284/127370
title: Multibeam Echosounder data collected during research cruise AR22 using a Kongsberg EM710 instrument system onboard the platform RV Neil Armstrong

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7732196
title: Functional annotation of Podosphaera xanthii transcriptome

description: Functional annotation of the <i>de novo</i> assembled transcriptome of <i>Podosphaera xanthii.</i><i></i>
DOI: 10.6084/m9.figshare.7732208
title: A randomized, double-blind, 3-way crossover, analog classroom study of SHP465 mixed amphetamine salts extended-release in adolescents with ADHD

description: <b>Objectives</b>: To evaluate the duration of efficacy, safety, and tolerability of SHP465 mixed amphetamine salts (MAS) extended-release versus placebo and immediate-release MAS (MAS IR) in adolescents with attention-deficit/hyperactivity disorder (ADHD). <b>Methods</b>: This phase 2, randomized, 3-period, 3-treatment crossover study compared SHP465 MAS (25/50 mg) with placebo and MAS IR (12.5 mg) in 13–17-year-old adolescents with ADHD having ADHD Rating Scale, Version IV (ADHD-RS-IV) total scores ≥24. A laboratory classroom served as a controlled environment during 16-hour observations, with efficacy assessed on the last day of each 7-day treatment period. The primary efficacy analysis compared SHP465 MAS with placebo on Permanent Product Measure of Performance (PERMP) total score averaged over the 16-hour postdose period using a mixed linear model. Comparisons were also conducted between MAS IR and placebo (for assay sensitivity) and between SHP465 MAS and MAS IR. PERMP problems attempted and answered correctly and ADHD symptoms based on ADHD-RS-IV; participant self-report; Swanson, Kotkin, Agler, M-Flynn, and Pelham Scale; and Revised Conner’s Parent Rating Scale scores were also evaluated. Safety and tolerability assessments included treatment-emergent adverse events and vital signs. <b>Results</b>: The intent-to-treat population included 84 participants. Least squares mean (95% CI) PERMP total score treatment differences significantly favored SHP465 MAS (combined 25/50 mg) over placebo for the average of all postdose assessment time points (41.26 [32.24, 50.29]; <i>P</i> P P P <b>Conclusions</b>: SHP465 MAS significantly improved PERMP total scores versus placebo from 2 to 16 hours postdose in adolescents with ADHD. The safety and tolerability profile of SHP465 MAS was consistent with previous reports of SHP465 MAS in individuals with ADHD.
DOI: 10.6084/m9.figshare.7732178
title: Supplementary Table 1: Vitamin D and Genotype

description: Supplementary Table 1: Vitamin D and Genotype RNA-seq data
DOI: 10.6084/m9.figshare.7732187
title: Supplementary Table 2: All Genes TSNE-clusters

description: Supplementary Table 2: All Genes TSNE-clusters RNA-seq data
DOI: 10.6084/m9.figshare.7732208.v1
title: A randomized, double-blind, 3-way crossover, analog classroom study of SHP465 mixed amphetamine salts extended-release in adolescents with ADHD

description: <b>Objectives</b>: To evaluate the duration of efficacy, safety, and tolerability of SHP465 mixed amphetamine salts (MAS) extended-release versus placebo and immediate-release MAS (MAS IR) in adolescents with attention-deficit/hyperactivity disorder (ADHD). <b>Methods</b>: This phase 2, randomized, 3-period, 3-treatment crossover study compared SHP465 MAS (25/50 mg) with placebo and MAS IR (12.5 mg) in 13–17-year-old adolescents with ADHD having ADHD Rating Scale, Version IV (ADHD-RS-IV) total scores ≥24. A laboratory classroom served as a controlled environment during 16-hour observations, with efficacy assessed on the last day of each 7-day treatment period. The primary efficacy analysis compared SHP465 MAS with placebo on Permanent Product Measure of Performance (PERMP) total score averaged over the 16-hour postdose period using a mixed linear model. Comparisons were also conducted between MAS IR and placebo (for assay sensitivity) and between SHP465 MAS and MAS IR. PERMP problems attempted and answered correctly and ADHD symptoms based on ADHD-RS-IV; participant self-report; Swanson, Kotkin, Agler, M-Flynn, and Pelham Scale; and Revised Conner’s Parent Rating Scale scores were also evaluated. Safety and tolerability assessments included treatment-emergent adverse events and vital signs. <b>Results</b>: The intent-to-treat population included 84 participants. Least squares mean (95% CI) PERMP total score treatment differences significantly favored SHP465 MAS (combined 25/50 mg) over placebo for the average of all postdose assessment time points (41.26 [32.24, 50.29]; <i>P</i> P P P <b>Conclusions</b>: SHP465 MAS significantly improved PERMP total scores versus placebo from 2 to 16 hours postdose in adolescents with ADHD. The safety and tolerability profile of SHP465 MAS was consistent with previous reports of SHP465 MAS in individuals with ADHD.
DOI: 10.7284/127368
title: Radiometer data collected during research cruise AR22 using a Biospherical QSR-2150 instrument system onboard the platform RV Neil Armstrong

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7732187.v1
title: Supplementary Table 2: All Genes TSNE-clusters

description: Supplementary Table 2: All Genes TSNE-clusters RNA-seq data
DOI: 10.7284/127369
title: Radiometer data collected during research cruise AR22 using a Eppley RAD instrument system onboard the platform RV Neil Armstrong

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7732196.v1
title: Data Citation 3_Functional annotation of P. xanthii transcriptome.xlsx

description: Functional annotation of the <i>de novo</i> assembled transcriptome of <i>Podosphaera xanthii.</i><i></i>
DOI: 10.7284/127362
title: Speedlog data collected during research cruise AR22 using a JRC JLN-550 instrument system onboard the platform RV Neil Armstrong

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/127358
title: Splitbeam Echosounder data collected during research cruise AR22 using a Kongsberg EK80 instrument system onboard the platform RV Neil Armstrong

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7731737
title: Silver nanoparticle-induced expression of proteins related to oxidative stress and neurodegeneration in an <i>in vitro</i> human blood-brain barrier model

description: Silver nanoparticles (AgNPs) have been reported to penetrate the central nervous system (CNS) and induce neurotoxicity. However, there is a paucity of understanding of the toxicity of AgNPs and their effect on the blood-brain barrier (BBB) including the underlying molecular mechanism(s) of action. Such information is important for the formulation of new strategies for delivery of biological therapeutics to central nervous system (CNS) targets. Using an in vitro BBB model and mass spectrometry-based proteomics, we investigated alterations in the proteomes of brain endothelial cells and astrocytes at different time points after AgNPs exposure (24 and 48 h). Our data showed that several proteins involved in neurodisorders and neurodegeneration were significantly upregulated in endothelial cells (e.g. 7-dehydrocholesterol reductase, zinc transporters 1 and 6), while proteins responsible for maintaining brain homeostasis were significantly downregulated (e.g anti-oxidative proteins glutathione peroxidase 1 and glutathione peroxidase 4). Many inflammatory pathways were significantly upregulated at 24 h post-AgNPs exposure (C9 pathway), while at 48 h proteins involved in BBB damage and anti-inflammatory responses were upregulated (quinoneoxidoreductase1 and glutamate cysteine ligase catalytic subunit) suggesting that by the later time point, cellular protection pathways had been activated to rescue the cells from AgNPs-induced toxicity. Our study suggests that in the initial stage of exposure, AgNPs exerted direct cellular stress on the endothelial cells by triggering a pro-inflammatory cascade. This study provides detailed insight into the toxic potency of AgNPs on in vitro BBB model and adds to the understanding of the adaptive role of BBB with regards to AgNPs-mediated toxicity.
DOI: 10.7284/127367
title: SSV (Sound Speed Velocimeter) data collected during research cruise AR22 using a AML SmartX P1S2 instrument system onboard the platform RV Neil Armstrong

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7731737.v1
title: Silver nanoparticle-induced expression of proteins related to oxidative stress and neurodegeneration in an <i>in vitro</i> human blood-brain barrier model

description: Silver nanoparticles (AgNPs) have been reported to penetrate the central nervous system (CNS) and induce neurotoxicity. However, there is a paucity of understanding of the toxicity of AgNPs and their effect on the blood-brain barrier (BBB) including the underlying molecular mechanism(s) of action. Such information is important for the formulation of new strategies for delivery of biological therapeutics to central nervous system (CNS) targets. Using an in vitro BBB model and mass spectrometry-based proteomics, we investigated alterations in the proteomes of brain endothelial cells and astrocytes at different time points after AgNPs exposure (24 and 48 h). Our data showed that several proteins involved in neurodisorders and neurodegeneration were significantly upregulated in endothelial cells (e.g. 7-dehydrocholesterol reductase, zinc transporters 1 and 6), while proteins responsible for maintaining brain homeostasis were significantly downregulated (e.g anti-oxidative proteins glutathione peroxidase 1 and glutathione peroxidase 4). Many inflammatory pathways were significantly upregulated at 24 h post-AgNPs exposure (C9 pathway), while at 48 h proteins involved in BBB damage and anti-inflammatory responses were upregulated (quinoneoxidoreductase1 and glutamate cysteine ligase catalytic subunit) suggesting that by the later time point, cellular protection pathways had been activated to rescue the cells from AgNPs-induced toxicity. Our study suggests that in the initial stage of exposure, AgNPs exerted direct cellular stress on the endothelial cells by triggering a pro-inflammatory cascade. This study provides detailed insight into the toxic potency of AgNPs on in vitro BBB model and adds to the understanding of the adaptive role of BBB with regards to AgNPs-mediated toxicity.
DOI: 10.7284/127361
title: Water Temperature data collected during research cruise AR22 using a Sea-Bird SBE-48 instrument system onboard the platform RV Neil Armstrong

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/127360
title: TSG (Thermosalinograph) data collected during research cruise AR22 using a Sea-Bird SBE-45 instrument system onboard the platform RV Neil Armstrong

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7731647
title: Table.docx

description: Demographic data and aneurysm characteristics in SC
and SAC are described in table 1. Comparison of procedure-related complications,
angiographic outcomes and clinical outcomes in SC and SAC in table 2. Analysis of risk
factors for aneurysmal recurrence in coiling ruptured wide-neck MCABAs in table
3. Analysis of risk factors for procedure-related
complications in coiling ruptured wide-neck MCABAs in table 4. Analysis of risk factors for clinical outcomes in
coiling ruptured wide-neck MCABAs in table 5. 

 

<b></b><i></i><sub></sub><sup></sup><br>
DOI: 10.7284/127401
title: ADCP (Acoustic Doppler Current Profiler) data collected during research cruise AR23-01 using a Hawaii UHDAS instrument system onboard the platform RV Neil Armstrong

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7731656
title: MAGAM II – prospective observational multicentre poisons centres study on eye exposures caused by cleaning products

description: <b>Objective:</b> Local effects on the eye following cleaning product exposures are frequently reported. According to EU chemicals legislation many cleaning products are labelled with Hazard Phrase 318 indicating risk of irreversible eye damage. The objectives of this study were to identify cleaning products with potential for irreversible eye damage by collecting human exposure data from poisons centres (PC), and to clarify to what degree exact product identification is possible during a PC telephone call. <b>Methods:</b> MAGAM II was a multicentre binational prospective observational PC study. All human eye exposures to detergents or maintenance products reported to nine PCs taking calls from the public and medical professionals during an 18-month period were included. The severity of eye effects was rated according to the WHO Poisoning Severity Score. <b>Results:</b> Five hundred and eighty-six cases were included. Product identification by name leading to formula information was successful in 533 cases (91%). Follow-up was successful in 528 exposures. Irrigation was performed in 94% of cases. Duration of symptoms was ≥24 hours in 73 patients (25%). 33 (6%) patients developed moderate eye injury. Healing was reported in all cases. The percentage of moderate cases was highest in the group of drain cleaners (25%), toilet cleaners (18%) and oven cleaners (15%). Products intended for professional use caused relatively more moderate eye injuries than products also intended for consumer use. <b>Conclusion:</b> MAGAM II has shown that PCs are able to identify formulas in sufficiently high quality as needed for product-directed toxicovigilance. The results underline the potential of PC exposure case data for product safety monitoring. The results indicate that irreversible eye damage is very rare after cleaning product exposure.
DOI: 10.6084/m9.figshare.7731656.v1
title: MAGAM II – prospective observational multicentre poisons centres study on eye exposures caused by cleaning products

description: <b>Objective:</b> Local effects on the eye following cleaning product exposures are frequently reported. According to EU chemicals legislation many cleaning products are labelled with Hazard Phrase 318 indicating risk of irreversible eye damage. The objectives of this study were to identify cleaning products with potential for irreversible eye damage by collecting human exposure data from poisons centres (PC), and to clarify to what degree exact product identification is possible during a PC telephone call. <b>Methods:</b> MAGAM II was a multicentre binational prospective observational PC study. All human eye exposures to detergents or maintenance products reported to nine PCs taking calls from the public and medical professionals during an 18-month period were included. The severity of eye effects was rated according to the WHO Poisoning Severity Score. <b>Results:</b> Five hundred and eighty-six cases were included. Product identification by name leading to formula information was successful in 533 cases (91%). Follow-up was successful in 528 exposures. Irrigation was performed in 94% of cases. Duration of symptoms was ≥24 hours in 73 patients (25%). 33 (6%) patients developed moderate eye injury. Healing was reported in all cases. The percentage of moderate cases was highest in the group of drain cleaners (25%), toilet cleaners (18%) and oven cleaners (15%). Products intended for professional use caused relatively more moderate eye injuries than products also intended for consumer use. <b>Conclusion:</b> MAGAM II has shown that PCs are able to identify formulas in sufficiently high quality as needed for product-directed toxicovigilance. The results underline the potential of PC exposure case data for product safety monitoring. The results indicate that irreversible eye damage is very rare after cleaning product exposure.
DOI: 10.7284/127387
title: CTD (Conductivity, Temperature, Depth) data collected during research cruise AR23-01 using a Sea-Bird SBE-911+ instrument system onboard the platform RV Neil Armstrong

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/133946
title: CTD (Conductivity, Temperature, Depth) data collected during research cruise EN630 using a Sea-Bird SBE-911+ instrument system onboard the platform RV Endeavor

description: Original (unprocessed) data collected during a Field_expedition