cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.23702115.v1
title: Carbohydrate, flavonoid, anthocyanin,total phenol, chlorophyll and mineral (K+) content development of wax apple fruit as affected by CPPU and NAA using swabbing technology

description: Abstract The study was conducted to investigate the effect of CPPU(2-Chloro-4-pyridyl-phenylurea) and NAA (Naphthaleneacetic acid) on the pigments, total phenol, flavonoid and mineral (K+) content in wax apple fruit. CPPU concentrations were 10, 15 and 20ppm (Expt.1) and 6, 12, 18ppm NAA were applied coming after swabbing technique (Expt.2). In Expt.1, the lowest fruit weight, fruit size and chlorophyll content was observed in control treatment. However, the highest fruit weight, fruit size and chlorophyll (SPAD) content was found in 15ppm CPPU. The most effective concentration was 15ppm CPPU for the earlier fruit maturity (color development) compared to other concentrations. Moreover, flavonoid, fructose, inverted sugar, total phenol and K+ were higher in 15ppm CPPU than control, 10 and 20ppm CPPU. In addition, anthocyanin was found increasing trend while developing the fruit maturity represented by color development. In Expt.2, chlorophyll was higher in 15ppm CPPU than control, 6, 18ppm NAA. Furthermore, flavonoid, fructose, inverted sugar, total phenol and K+ content were higher in 12ppm NAA than control, 6 and 18ppm NAA. Besides, the maximum anthocyanin was found in 12ppm NAA. Finally it seemed that 15ppm CPPU and 12ppm NAA were the best concentration for fruit growth and biochemical contents development in wax apple.
DOI: 10.6084/m9.figshare.23803726
title: Cross-cultural adaptation of the milestones project in otolaryngology for the brazilian reality

description: ABSTRACT Introduction: competency-based medical education is well established, but there is a worldwide shortage of instruments capable of assessing these doctors in training. Objective: to validate the instrument The Otolaryngology - Head and Neck Surgery Milestone Project for use in Residency Programs in Otorhinolaryngology in Brazil. Method: The study had 5 stages. In stage I, two independent translations of the Milestones Project in otorhinolaryngology were carried out. In step II, a synthesis of the translations was performed. Subsequently, the competencies required by the Brazilian Association of Otorhinolaryngology for training otorhinolaryngologists in Brazil were added. In step III, a back-translation of the instrument was carried out and sent to the original authors. Then, the instrument was sent to be evaluated by a committee of 8 experts. In stage IV, each expert made comments about each of the items, and after analyzing the suggestions, a new instrument was created. In stage V, this instrument was sent for evaluation by otorhinolaryngologists across the country. Results: after translations and expert evaluation, an instrument with 19 items was created. The instrument was submitted to analysis by Otorhinolaryngologists from all over Brazil. Acceptance percentages were: applicability (99.25%), reliability (99.5%), reproducibility (98.6%), reliability (93.84%), relevance (93.15%). Conclusion: the created instrument was considered applicable, reproducible, relevant, reliable and trustworthy, presenting content validity.
DOI: 10.6084/m9.figshare.23803726.v1
title: Cross-cultural adaptation of the milestones project in otolaryngology for the brazilian reality

description: ABSTRACT Introduction: competency-based medical education is well established, but there is a worldwide shortage of instruments capable of assessing these doctors in training. Objective: to validate the instrument The Otolaryngology - Head and Neck Surgery Milestone Project for use in Residency Programs in Otorhinolaryngology in Brazil. Method: The study had 5 stages. In stage I, two independent translations of the Milestones Project in otorhinolaryngology were carried out. In step II, a synthesis of the translations was performed. Subsequently, the competencies required by the Brazilian Association of Otorhinolaryngology for training otorhinolaryngologists in Brazil were added. In step III, a back-translation of the instrument was carried out and sent to the original authors. Then, the instrument was sent to be evaluated by a committee of 8 experts. In stage IV, each expert made comments about each of the items, and after analyzing the suggestions, a new instrument was created. In stage V, this instrument was sent for evaluation by otorhinolaryngologists across the country. Results: after translations and expert evaluation, an instrument with 19 items was created. The instrument was submitted to analysis by Otorhinolaryngologists from all over Brazil. Acceptance percentages were: applicability (99.25%), reliability (99.5%), reproducibility (98.6%), reliability (93.84%), relevance (93.15%). Conclusion: the created instrument was considered applicable, reproducible, relevant, reliable and trustworthy, presenting content validity.
DOI: 10.6084/m9.figshare.23701918.v1
title: Successive applications of gibberellic acid in alternate bearing mandarins

description: Abstract Gibberellins can promote the inhibition of floral induction in citrus in order to reduce alternate bearing. However, not much is known about the responsiveness of Citrus deliciosa to exogenous applications of gibberellic acid. Furthermore, the successive application of gibberellins is barely studied. The main objective of this work was to evaluate the effect of successive applications of gibberellic acid (GA3) on the reduction of spring flowering subsequent to low fruit load periods (off-year) in ‘Montenegrina’ and ‘Rainha’ mandarin trees, in southern Brazil. The treatments consisted of one to four successive applications of GA3 (40 mg L-1) with 21-day interval in off-year trees. Applications began in May and ended in July. There was a significant reduction in sprouting and flowering of ‘Montenegrina’ mandarin with more than two GA3 successive applications compared to the control. To ‘Rainha’ mandarin, only two GA3 applications reduced the sprouting and solely one GA3 application was enough to reduce sprouting in relation to the control. GA3 use reduced sprouting and flowering of Montenegrina and Rainha cultivars. The orchard age may be related to its level of alternate bearing and, therefore, to the greater or lesser sensitivity of gibberellin applications.
DOI: 10.6084/m9.figshare.23701918
title: Successive applications of gibberellic acid in alternate bearing mandarins

description: Abstract Gibberellins can promote the inhibition of floral induction in citrus in order to reduce alternate bearing. However, not much is known about the responsiveness of Citrus deliciosa to exogenous applications of gibberellic acid. Furthermore, the successive application of gibberellins is barely studied. The main objective of this work was to evaluate the effect of successive applications of gibberellic acid (GA3) on the reduction of spring flowering subsequent to low fruit load periods (off-year) in ‘Montenegrina’ and ‘Rainha’ mandarin trees, in southern Brazil. The treatments consisted of one to four successive applications of GA3 (40 mg L-1) with 21-day interval in off-year trees. Applications began in May and ended in July. There was a significant reduction in sprouting and flowering of ‘Montenegrina’ mandarin with more than two GA3 successive applications compared to the control. To ‘Rainha’ mandarin, only two GA3 applications reduced the sprouting and solely one GA3 application was enough to reduce sprouting in relation to the control. GA3 use reduced sprouting and flowering of Montenegrina and Rainha cultivars. The orchard age may be related to its level of alternate bearing and, therefore, to the greater or lesser sensitivity of gibberellin applications.
DOI: 10.6084/m9.figshare.23701880.v1
title: Effect of fruits maturation stage and vegetal regulators in the physiological quality of seeds sweet passion fruit cv. BRS Mel do Cerrado

description: Abstract This study aimed to evaluate the effect of fruit maturation stages and pre-germination treatments with plant regulators on the physiological quality of seeds of cv. BRS Mel do Cerrado. Two experiments were carried out, germination and emergence, installed in a completely randomized design in a 3 x 2 factorial arrangement, with three stages maturation (1-partially ripe fruits; 2-fully ripe fruits and 3-senescent fruits) and two pre-germination treatments (1. [GA4+7 +N-(phenylmethyl)-aminopurine (300 ppm)] and 2. distilled water), forming six treatments with four replications of 50 seeds. The evaluated characteristics were germination percentage at 14 and 35 days, germination speed index (GSI), emergence percentage and emergence speed index (ESI). Germination at 14 days, GSI and seedling emergence were not affected by the maturation stage, however germination and GSI were higher when the plant regulator was used. The final percentage of germination was higher in seeds taken from partially ripe fruits and treated with regulators and a higher ESI was observed for seeds from senescent fruits and treated with regulator. Seeds treated with plant regulators are more vigorous and have a higher rate of seedling emergence.
DOI: 10.6084/m9.figshare.23701880
title: Effect of fruits maturation stage and vegetal regulators in the physiological quality of seeds sweet passion fruit cv. BRS Mel do Cerrado

description: Abstract This study aimed to evaluate the effect of fruit maturation stages and pre-germination treatments with plant regulators on the physiological quality of seeds of cv. BRS Mel do Cerrado. Two experiments were carried out, germination and emergence, installed in a completely randomized design in a 3 x 2 factorial arrangement, with three stages maturation (1-partially ripe fruits; 2-fully ripe fruits and 3-senescent fruits) and two pre-germination treatments (1. [GA4+7 +N-(phenylmethyl)-aminopurine (300 ppm)] and 2. distilled water), forming six treatments with four replications of 50 seeds. The evaluated characteristics were germination percentage at 14 and 35 days, germination speed index (GSI), emergence percentage and emergence speed index (ESI). Germination at 14 days, GSI and seedling emergence were not affected by the maturation stage, however germination and GSI were higher when the plant regulator was used. The final percentage of germination was higher in seeds taken from partially ripe fruits and treated with regulators and a higher ESI was observed for seeds from senescent fruits and treated with regulator. Seeds treated with plant regulators are more vigorous and have a higher rate of seedling emergence.
DOI: 10.48512/xcv8476569
title: Ready or Not An Archaeological KSA Needs Assessment

description: Debates about the best means of preparing archaeologists continue. This article reviews data from 674 archaeological job postings to assess in-demand archaeological knowledge, skills, and abilities. The needs assessment reveals American archaeology’s demand for dynamic, highly skilled professionals capable of identifying, preserving, and protecting the past. The skills demanded in archaeology job postings are the skills necessary to succeed as an archaeologist in any sector and the same skills necessary to meet the challenges faced by discipline more generally.
DOI: 10.6084/m9.figshare.23803776
title: Supplementary Material for: Association of lifelong cognitive reserve with dementia and mild cognitive impairment among older adults with limited formal education: a population-based cohort study

description: Introduction: Early-life educational attainment contributes to cognitive reserve (CR). We investigated the associations of lifelong CR with dementia and mild cognitive impairment (MCI) among older people with limited formal education. Methods: This population-based cohort study included 2127 dementia-free participants (≥60 years; 59.4% women; 81.5% with no or elementary school) who were examined at baseline (August-December 2014) and follow-up (March-September 2018). Lifelong CR score at baseline was generated from six lifespan intellectual factors. Dementia, MCI, and their subtypes were defined according to the international criteria. Data were analyzed using Cox proportional-hazards models. Results: During the total of 8330.6 person-years of follow-up, 101 persons were diagnosed with dementia, including 74 with AD and 26 with VaD. The high (versus low) tertile of lifelong CR score was associated with multivariable-adjusted hazards ratio (95% confidence interval) of 0.28 (0.14–0.55) for dementia and 0.18 (0.07–0.48) for AD. The association between higher CR and reduced AD risk was significant in people aged 60-74 but not in those aged≥75 years (P-for-interaction=0.011). Similarly, among MCI-free people at baseline (n=1635), the high (versus low) tertile of lifelong CR score was associated with multivariable-adjusted hazard ratio of 0.51 (0.38–0.69) for MCI and 0.46 (0.33–0.64) for amnestic MCI. Lifelong CR was not related to VaD or non-amnestic MCI. Discussion: High lifelong CR is associated with reduced risks of dementia and MCI, especially AD and amnestic MCI. It highlights the importance of lifelong CR in in maintaining late-life cognitive health even among people with no or limited education.
DOI: 10.5519/qd.3yeko6fk
title: Query on the Natural History Museum Data Portal (data.nhm.ac.uk) (25 records)
DOI: 10.6084/m9.figshare.23803791
title: Supplementary Material for: Long-term trajectories of biomarkers, functional, and echocardiographic parameters in patients with chronic heart failure from dilated or ischaemic cardiomyopathy

description: Introduction: The long-term evolution of clinical, echocardiographic and laboratory parameters of cardiac function in patients with chronic heart failure (HF) with either reduced (HFrEF) or mildly reduced (HFmrEF) left ventricular ejection fraction (LVEF) is incompletely characterized. Methods: We identified patients with chronic stable HF who presented at least twice to a university HF outpatient clinic between 1995 and 2021. Trajectories of NYHA functional class, LVEF, left ventricular internal enddiastolic diameter (LVIDD), NT-proBNP concentrations and HF treatment over ten years follow-up were analysed using fractional polynomials. Analyses were repeated after stratifying patients according to aetiology (ischemic vs. dilated) or HF category (HFrEF vs. HFmrEF). Results: A total of 2,132 patients were included, of whom 51% had ischemic and 49% had dilated HF. 86% and 14% were classified as HFrEF and HFmrEF, respectively. Mean LVEF was 28±10%, and median NT-proBNP and eGFR values were 1,170 (385-3,176) pmol/L and 81 (62-100) ml/min/1.73m², respectively. Median follow-up was 5.2 (2.6-9.2) years. Overall, NYHA functional class and LVIDD trajectories were U-shaped, whereas LVEF and NT-proBNP concentrations markedly improved during the first year and remained stable thereafter. However, the evolution of HF parameters significantly differed with respect to HF category and aetiology, with greater improvements seen in patients with HFrEF of non-ischemic origin. Improvements in HF variables were associated with optimization of HF therapy, notably with initiation and up-titration of renin-angiotensin-system blockers. Discussion/Conclusion: This study provides insights into the natural history of HF in a large cohort of well-treated chronic HF outpatients with respect to subgroups of HF and different etiologist.
DOI: 10.6084/m9.figshare.23803791.v1
title: Supplementary Material for: Long-term trajectories of biomarkers, functional, and echocardiographic parameters in patients with chronic heart failure from dilated or ischaemic cardiomyopathy

description: Introduction: The long-term evolution of clinical, echocardiographic and laboratory parameters of cardiac function in patients with chronic heart failure (HF) with either reduced (HFrEF) or mildly reduced (HFmrEF) left ventricular ejection fraction (LVEF) is incompletely characterized. Methods: We identified patients with chronic stable HF who presented at least twice to a university HF outpatient clinic between 1995 and 2021. Trajectories of NYHA functional class, LVEF, left ventricular internal enddiastolic diameter (LVIDD), NT-proBNP concentrations and HF treatment over ten years follow-up were analysed using fractional polynomials. Analyses were repeated after stratifying patients according to aetiology (ischemic vs. dilated) or HF category (HFrEF vs. HFmrEF). Results: A total of 2,132 patients were included, of whom 51% had ischemic and 49% had dilated HF. 86% and 14% were classified as HFrEF and HFmrEF, respectively. Mean LVEF was 28±10%, and median NT-proBNP and eGFR values were 1,170 (385-3,176) pmol/L and 81 (62-100) ml/min/1.73m², respectively. Median follow-up was 5.2 (2.6-9.2) years. Overall, NYHA functional class and LVIDD trajectories were U-shaped, whereas LVEF and NT-proBNP concentrations markedly improved during the first year and remained stable thereafter. However, the evolution of HF parameters significantly differed with respect to HF category and aetiology, with greater improvements seen in patients with HFrEF of non-ischemic origin. Improvements in HF variables were associated with optimization of HF therapy, notably with initiation and up-titration of renin-angiotensin-system blockers. Discussion/Conclusion: This study provides insights into the natural history of HF in a large cohort of well-treated chronic HF outpatients with respect to subgroups of HF and different etiologist.
DOI: 10.6084/m9.figshare.23803794
title: Supplementary Material for: Association of lifelong cognitive reserve with dementia and mild cognitive impairment among older adults with limited formal education: a population-based cohort study

description: Introduction: Early-life educational attainment contributes to cognitive reserve (CR). We investigated the associations of lifelong CR with dementia and mild cognitive impairment (MCI) among older people with limited formal education. Methods: This population-based cohort study included 2127 dementia-free participants (≥60 years; 59.4% women; 81.5% with no or elementary school) who were examined at baseline (August-December 2014) and follow-up (March-September 2018). Lifelong CR score at baseline was generated from six lifespan intellectual factors. Dementia, MCI, and their subtypes were defined according to the international criteria. Data were analyzed using Cox proportional-hazards models. Results: During the total of 8330.6 person-years of follow-up, 101 persons were diagnosed with dementia, including 74 with AD and 26 with VaD. The high (versus low) tertile of lifelong CR score was associated with multivariable-adjusted hazards ratio (95% confidence interval) of 0.28 (0.14–0.55) for dementia and 0.18 (0.07–0.48) for AD. The association between higher CR and reduced AD risk was significant in people aged 60-74 but not in those aged≥75 years (P-for-interaction=0.011). Similarly, among MCI-free people at baseline (n=1635), the high (versus low) tertile of lifelong CR score was associated with multivariable-adjusted hazard ratio of 0.51 (0.38–0.69) for MCI and 0.46 (0.33–0.64) for amnestic MCI. Lifelong CR was not related to VaD or non-amnestic MCI. Discussion: High lifelong CR is associated with reduced risks of dementia and MCI, especially AD and amnestic MCI. It highlights the importance of lifelong CR in in maintaining late-life cognitive health even among people with no or limited education.
DOI: 10.6084/m9.figshare.23803794.v1
title: Supplementary Material for: Association of lifelong cognitive reserve with dementia and mild cognitive impairment among older adults with limited formal education: a population-based cohort study

description: Introduction: Early-life educational attainment contributes to cognitive reserve (CR). We investigated the associations of lifelong CR with dementia and mild cognitive impairment (MCI) among older people with limited formal education. Methods: This population-based cohort study included 2127 dementia-free participants (≥60 years; 59.4% women; 81.5% with no or elementary school) who were examined at baseline (August-December 2014) and follow-up (March-September 2018). Lifelong CR score at baseline was generated from six lifespan intellectual factors. Dementia, MCI, and their subtypes were defined according to the international criteria. Data were analyzed using Cox proportional-hazards models. Results: During the total of 8330.6 person-years of follow-up, 101 persons were diagnosed with dementia, including 74 with AD and 26 with VaD. The high (versus low) tertile of lifelong CR score was associated with multivariable-adjusted hazards ratio (95% confidence interval) of 0.28 (0.14–0.55) for dementia and 0.18 (0.07–0.48) for AD. The association between higher CR and reduced AD risk was significant in people aged 60-74 but not in those aged≥75 years (P-for-interaction=0.011). Similarly, among MCI-free people at baseline (n=1635), the high (versus low) tertile of lifelong CR score was associated with multivariable-adjusted hazard ratio of 0.51 (0.38–0.69) for MCI and 0.46 (0.33–0.64) for amnestic MCI. Lifelong CR was not related to VaD or non-amnestic MCI. Discussion: High lifelong CR is associated with reduced risks of dementia and MCI, especially AD and amnestic MCI. It highlights the importance of lifelong CR in in maintaining late-life cognitive health even among people with no or limited education.
DOI: 10.6084/m9.figshare.23803824
title: Supplementary Material for: Long-term trajectories of biomarkers, functional, and echocardiographic parameters in patients with chronic heart failure from dilated or ischaemic cardiomyopathy

description: Introduction: The long-term evolution of clinical, echocardiographic and laboratory parameters of cardiac function in patients with chronic heart failure (HF) with either reduced (HFrEF) or mildly reduced (HFmrEF) left ventricular ejection fraction (LVEF) is incompletely characterized. Methods: We identified patients with chronic stable HF who presented at least twice to a university HF outpatient clinic between 1995 and 2021. Trajectories of NYHA functional class, LVEF, left ventricular internal enddiastolic diameter (LVIDD), NT-proBNP concentrations and HF treatment over ten years follow-up were analysed using fractional polynomials. Analyses were repeated after stratifying patients according to aetiology (ischemic vs. dilated) or HF category (HFrEF vs. HFmrEF). Results: A total of 2,132 patients were included, of whom 51% had ischemic and 49% had dilated HF. 86% and 14% were classified as HFrEF and HFmrEF, respectively. Mean LVEF was 28±10%, and median NT-proBNP and eGFR values were 1,170 (385-3,176) pmol/L and 81 (62-100) ml/min/1.73m², respectively. Median follow-up was 5.2 (2.6-9.2) years. Overall, NYHA functional class and LVIDD trajectories were U-shaped, whereas LVEF and NT-proBNP concentrations markedly improved during the first year and remained stable thereafter. However, the evolution of HF parameters significantly differed with respect to HF category and aetiology, with greater improvements seen in patients with HFrEF of non-ischemic origin. Improvements in HF variables were associated with optimization of HF therapy, notably with initiation and up-titration of renin-angiotensin-system blockers. Discussion/Conclusion: This study provides insights into the natural history of HF in a large cohort of well-treated chronic HF outpatients with respect to subgroups of HF and different etiologist.