cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.22308934.v1
title: Supplementary Material for: Impact of Long-Term Antithrombotic and Statin Therapy on the Clinical Outcome in Patients with Cavernous Malformations of the Central Nervous System: A Single-Center Case Series of 428 Patients

description: <b><i>Introduction:</i></b> Literature regarding the safety and efficacy of antithrombotic (antiplatelet or anticoagulant) therapy and statins in patients with cavernous malformations (CMs) of the central nervous system is sparse, resulting in uncertainty about its use in clinical practice. The aim of this study was to analyze the impact of antithrombotic therapy and statins on the risk of hemorrhage and focal neurological deficit in patients with CMs. <b><i>Methods:</i></b> The authors’ institutional database was screened for all patients with CMs of the central nervous system treated at their institution between 2006 and 2018. Patients with radiological and/or histological diagnosis of CMs, clinical baseline characteristics, available patient’s medication history, and follow-up data were included in this study. Time-to-event probability (hemorrhage or focal neurological deficit) as well as the number of events (hemorrhage or focal neurological deficit) during follow-up were assessed in patients who were categorized according to their medical treatment (antithrombotic therapy, statins, combined therapy, or no treatment). <b><i>Results:</i></b> Four hundred twenty-eight patients with CMs were eligible and included in the final analysis. Sixty-nine (16.1%) patients were on long-term antithrombotic therapy and 46 (10.6%) on long-term statins, of whom 31 patients were on a combination of both. The probability of experiencing first hemorrhage or focal neurological deficit was less likely in patients on antiplatelet therapy (HR 0.09, 95% CI 0.021–0.39, <i>p</i> = 0.001), anticoagulant therapy (HR 0.12, 95% CI 0.016–0.85, <i>p</i> = 0.034), or the combination thereof (HR 0.12, 95% CI 0.016–0.93, <i>p</i> = 0.043) compared to patients with no antithrombotic treatment. The number of hemorrhages and focal neurological deficits were significantly lower in patients on antithrombotic therapy compared to patients on no treatment during follow-up. In patients on statins alone, the time-to-event probability was comparable to that of patients on no treatment (HR 0.91, 95% CI 0.438–1.91, <i>p</i> = 0.812), and the number of events was similar to patients on no treatment. <b><i>Conclusion:</i></b> The results of our study provide further evidence that antithrombotic therapy alone or in combination with statins in patients with CMs of the central nervous system does not increase the risk of hemorrhage or focal neurological deficit but, on the contrary, may have some benefit.
DOI: 10.6084/m9.figshare.7928633.v1
title: gVCF_NA19351

description: 1000 Genomes gVCF mapped to hs37d5 for NA19351. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307
DOI: 10.6084/m9.figshare.24431806.v1
title: Sawai et al_microsatellite data.xlsx

description: Microsatellite genotyping data (30 loci) and geographical locations of 1,062 samples from wild boar (Sus scrofa leucomystax) in Japan. The data were analysed in the article: "Assessing population structure and migration patterns of wild boar (Sus scrofa) in Japan".
DOI: 10.6084/m9.figshare.28830974.v2
title: External data

description: Prediction models
DOI: 10.1184/r1/13834643.v1
title: Cognitive & Motor Skill Transfer Across Speeds: A Video Game Study (Data)

description: This zipped folder contains the data that was used in the Cognitive & Motor Skill Transfer project. There are 5 different items: Human data (game logs - event files), model data (game logs - event files), human game scores, model game scores, and the R spreadsheets that were input for statistical analyses and creation of figures. The README for these data can be found within the zipped folder.<br>The corresponding software for this project can be found on KiltHub at https://doi.org/10.1184/R1/13836224 <br>
DOI: 10.6084/m9.figshare.11510100.v1
title: Symmetric FLAIR atlas (brain and skull)

description: Symmetric FLAIR atlas with brain and skull
DOI: 10.6084/m9.figshare.26720712.v1
title: Additional file 7 of The lack of Tex44 causes severe subfertility with flagellar abnormalities in male mice

description: Supplementary Material 7: Table 5. Raw data corresponding to Figures 3b,c,d, 4b and 7b.
DOI: 10.6084/m9.figshare.21900221.v1
title: Factors determining farmers’ access to agricultural credit in Turkey

description: ABSTRACT: This study assessed the parameters determining the access of producers to agricultural credit in Turkey. This research was carried out in the production areas par excellence of the country. A total of 409 producers have been surveyed. The data collected was collected during the first quarter of 2021 and relates to the socio-economic and demographic characteristics of producers as well as the factors likely to influence their access to agricultural credit. The analysis of the results from the logistic regression model produced shows that the access of producers to agricultural credit is determined by their socio-economic and demographic characteristics. These parameters are level of education, degree of involvement in agricultural activities, social security status, household size and whether you own a tractor. Given the importance of agricultural credit for the agricultural sector; it is therefore, imperative to facilitate its access to producers.
DOI: 10.15468/dl.5upz9k
title: Occurrence Download

description: A dataset containing 3517 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Observation, Human Observation, Machine Observation, Living Specimen)"
 ]
 }
 },
 "TaxonKey is Macaria notata (Linnaeus, 1758)"
 ]
}

 The dataset includes 3517 records from 78 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0009479-250426092105405/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.25715559.v1
title: Post Focus Group Responses

description: Nepal's National Health Insurance (NHIP) enrollees and non-enrollees participated in various focus group discussion to share their experiences and perceptions regarding NHIP. This post-focus group survey was conducted to understand the socio-demographic profile of those participants.
DOI: 10.6084/m9.figshare.13469529.v1
title: Abstract and Survey With Results.docx

description: A survey was conducted to determine medical librarians' knowledge of the types of clinical trials and their comfort levels in locating clinical trials for systematic reviews. The article was published in the April 2021 issue of the Journal of the Medical Library Association. The abstract, survey, and compiled results are available in this document.
DOI: 10.6084/m9.figshare.14339729.v1
title: Supplementary Material for: Adjuvant Chemotherapy in High-Risk Prostate Cancer Patients after Primary Local Therapy: Recurrence, Metastasis, and Survival – A Meta-Analysis

description: <b><i>Context:</i></b> Several randomized clinical trials (RCTs) have recently tested adjuvant chemotherapy to high-risk prostate cancer patients (PCA) after primary local therapy. <b><i>Objective:</i></b> The aim of the study was to perform a systematic review and meta-analysis of RCTs evaluating the adjuvant chemotherapy in high-risk prostate cancer patients after primary local therapy. The primary endpoint was overall survival (OS). The secondary endpoint was disease-free survival (DFS) and biochemical recurrence-free survival (BRFS). <b><i>Methods:</i></b> A systematic review of PubMed/Medline, Embase, and Cochrane databases was performed to identify relevant studies published in English up to March 2020. Six trials were selected for inclusion. <b><i>Results:</i></b> There were 7 studies included in the present study. The meta-analysis did not show a significant OS benefit from adjuvant chemotherapy in patients with high-risk prostate cancer after primary local therapy (hazard ratio [HR]: 0.87; 95% confidence interval [CI], 0.72–1.05; <i>p =</i> 0.15). But docetaxel in patients with high-risk prostate cancer after primary local therapy was associated with a slightly OS improvement (HR: 0.79; 95% CI, 0.63–0.98; <i>p</i> = 0.03). It also did not show a significant benefit in DFS and BRFS in patients with high-risk prostate cancer (HR: 0.89, 95% CI, 0.75–1.06, <i>p</i> = 0.18; HR: 0.85, 95% CI, 0.69–1.06, <i>p</i> = 0.16). <b><i>Conclusions:</i></b> This meta-analysis shows a slightly OS benefit from docetaxel in patients with high-risk prostate cancer after primary local therapy. It did not show a significant benefit in DFS and BRFS from adjuvant chemotherapy in patients with high-risk prostate cancer.
DOI: 10.6084/m9.figshare.16393380.v1
title: Chromosomal level genome of Ilex asprella and insight into antiviral metabolite pathway

description: <i>Ilex</i> is a monogeneric plant group in the family Aquifoliaceae. In <i>Lingnan</i> area of China, <i>Ilex asprella</i> is commonly used as a major component of cooling beverages. According to the records of Traditional Chinese Medicine (TCM), root of <i>I. asprella </i>was effective in treating lung infections and relieving organ inflammations. The pharmacological activities of <i>I. asprella </i>have been proved by biochemical research in recent years. With reference to the <i>in vivo</i> studies, ethanolic extract of <i>I.</i> <i>asprella </i>can significantly decrease the viral load of influenza A virus. Lung index, which is an indicator of lung edema, was also massively reduced. By using the column chromatography, the main anti-influenza compound Asprellcosides B, which is an ursane type triterpenoid saponin, was discovered. In fact, triterpenoid saponin is one of the most common biological active chemical in <i>I.</i> <i>asprella.</i> Other than treating influenza virus, triterpenoid Asprellanoside A were also showing anti-herpes simplex virus 1 (HSV-1) activity. Anti-cancer and anti-complement triterpenoids have also been found in <i>I. asprella</i>.
DOI: 10.6084/m9.figshare.28613747.v1
title: De-identified Dataset: Implementation of Group Antenatal Care (G-ANC) at Health Posts in Ethiopia

description: This deidentified dataset is from an effectiveness study evaluating Group Antenatal Care (G-ANC) at health posts in Ethiopia. The study aimed to assess the effectiveness of implementing G-ANC in increasing antenatal care attendance and facility delivery rates.
DOI: 10.6084/m9.figshare.28045040.v1
title: GVHD RAG Data with Production and Interaction Type

description: A classic retrieval augmented generation (RAG) Q&A bot that answers questions about the GVHD medical condition.
DOI: 10.6084/m9.figshare.28480604.v1
title: Raw data for the paper

description: The objective of this study was to examine the therapeutic effects of Astragalus polysaccharide and <i>Clostridium butyricum</i> on liver injury induced by a simulated space environment in mice.
DOI: 10.6084/m9.figshare.26876287.v2
title: Raw data - Interests of Google users in information pollution terminologies: An infodemiology study

description: Raw data of the manuscript "<i>Interests of Google users in information pollution terminologies: An infodemiology study</i>"
DOI: 10.6084/m9.figshare.14695787.v1
title: Diamondiferous kimberlites from recently explored Upper Muna field (Siberian craton):petrology, mineralogy and geochemistry insights

description: Table S6. Rb-Sr isotope composition of kimberlites
DOI: 10.6084/m9.figshare.15104580.v1
title: Raw data: R1 and R2 for each mite and mucus samples

description: Raw reads for mite and mucus samples. NCBI SRA submissions were temporary down; we will update the SRA accession numbers here as soon as possible<br>
DOI: 10.6084/m9.figshare.25911982.v1
title: sclarea_annotation

description: Gene annotation for the <i>S. sclarea</i> genome was performed using a combination of ab initio prediction, homology-based methods, and transcriptome data.
DOI: 10.6084/m9.figshare.28776011.v1
title: Industry_awareness_of_green_practices_Interview_Questions.xlsx

description: Supplementary data of research Survey_Questions_Industry_Awareness_Adoption_Of_Green_practices
DOI: 10.6084/m9.figshare.26461531.v1
title: Suplemen: Menguasai Visualisasi Data (Prinsip, Teknik, dan Praktik Menggunakan DataWrapper)

description: File ini berisi 3 data yang berbeda yang muncul pada sheet secara berturut-turut: perceraian, wisatawan, dan haji. Dataset ini digunakan sebagai bahan praktik pada “DataViz: Bagaimana Menyajikan Data Riset secara Visual Menggunakan DataWrapper” yang diselenggarakan oleh Relawan Jurnal IndonesiaKantor Pusat RJI, Yogyakarta | Kamis, 25 Juli 2024<b>Sumber data:</b>BPS, Jumlah Perceraian Menurut Provinsi dan Faktor [link]BPS, Jumlah Jemaah Haji yang Diberangkatkan ke Tanah Suci Mekah Menurut Provinsi [link]BPS, Jumlah Kunjungan Wisatawan Mancanegara ke Indonesia Menurut Kebangsaan (Kunjungan) [link]<br>Salindia materi: https://www.erickunto.com/2024/08/menguasai-visualisasi-data-prinsip-teknik-dan-praktik-menggunakan-datawrapper.html<br>
DOI: 10.6084/m9.figshare.23578896.v1
title: Supplementary Material for: Effects of Acute Exercise on Affect, Anxiety, and Self-Esteem in Poly-Substance Dependent Inpatients

description: <b><i>Introduction:</i></b> Negative affect and anxiety frequently precede the onset of drug use in those with substance use disorder (SUD). Low self-esteem may increase the risk of relapse. We examined the short-term effects of exercise on affect, anxiety, and self-esteem in inpatients with poly-SUD. <b><i>Methods:</i></b> This is a multicenter randomized control trial (RCT) with a crossover design. Thirty-eight inpatients (37.3 ± 6.4 years; 84% male) from three clinics participated in 45 min of soccer, circuit training, and control condition (psychoeducation) in a random order. Positive and negative affect (PANAS), state anxiety (single item), and self-esteem (Rosenberg SE-scale) were measured immediately before, immediately after, 1-h, 2-h, and 4-h post-exercise. Heart rate and ratings of perceived exertion were taken. Effects were assessed using linear mixed effects models. <b><i>Results:</i></b> Compared to the control condition, there were significant post-exercise improvements in positive affect (β = 2.99, CI = 0.39: 5.58), self-esteem (β = 1.84, CI = 0.49: 3.20), and anxiety (β = −0.69, CI = −1.34: −0.04) after circuit training (shown) and soccer. Effects persisted 4-h post-exercise. Reductions in negative affect were observed 2-h (circuit training: β = −3.39, CI = −6.35: −1.51) and 4-h (soccer: β = −3.71, CI = −6.03: −1.39) post-exercise, respectively. <b><i>Conclusion:</i></b> Moderately strenuous exercise undertaken in naturalistic settings may improve mental health symptoms in poly-SUD inpatients for up to 4-h post-exercise.
DOI: 10.6084/m9.figshare.5124421.v1
title: Supplementary Material for: Secreted Expression of a Hyperthermophilic α-Amylase Gene from <b><i>Thermococcus</i></b> sp. HJ21 in <b><i>Bacillus subtilis</i></b>

description: The hyperthermophilic α-amylase from <i>Thermococcus</i> sp. HJ21 possesses unique traits (Ca<sup>2+</sup>-independent thermostability and optimal temperature of 95°C) that make it a great potential candidate for use in the food industry. However, this Archaea isolated from a deep-sea thermal vent requires strict control of culture conditions and produces only small amounts of α-amylase. To solve these problems, the α-amylase gene was cloned and expressed in <i>Bacillus subtilis</i>, which is an ideal food-grade host for heterologous protein expression. To express high levels of this α-amylase in <i>B. subtilis</i>, the promoters P<sub><i>grac</i></sub>, P<sub><i>xylA</i></sub>, P43, and P<sub><i>hag</i></sub> were used to construct four different expression vectors for testing. The vector containing the P<sub><i>xylA</i></sub> promoter was found to have the highest transcriptional activity and produce the highest amylase activity (19.6 U/ml). To test the secretion efficiency of signal peptides in <i>B. subtilis</i>, three signal peptides were cloned and fused to the α-amylase gene (lacking its native signal peptide). The optimal signal peptide was S<sub><i>amyQ</i></sub>, with a secretion efficiency of approximately 90%. These results indicate that the promoter P<sub><i>xylA</i></sub> and signal peptide S<sub><i>amyQ</i></sub> tested in this study may be useful for the expression and secretion of archaeal proteins in <i>B. subtilis</i>.
DOI: 10.6084/m9.figshare.26840590.v1
title: Supplementary Material for: Diagnostic Accuracy of Papanicolaou Society of Cytopathology System for Reporting Respiratory Cytology: A Systematic Review and Meta-Analysis

description: Introduction
This study conducts the first meta-analysis to evaluate the diagnostic accuracy and the aggregated risk of malignancy associated with each category of the Papanicolaou Society of Cytopathology (PSC) system for reporting respiratory cytology.
Methods
A systematic search was conducted in PubMed, Scopus, and Web of Science using the keywords “(Lung, Respiratory specimens) AND (Papanicolaou Society of Cytopathology System).” Articles were assessed for risk of bias using the QUADAS-2 tool. After excluding inadequate samples, sensitivity and specificity for various cut-off points. Summary receiver operating characteristic (sROC) curves and diagnostic odds ratios (DOR) were pooled to assess diagnostic accuracy.
Results
Five studies, totaling 3489 cases, were included. Sensitivity and specificity for the "Atypical and higher risk categories" considered positive were 60% (95% CI, 51%-68%) and 87% (95% CI, 81%-92%), respectively. For the "Suspicious for malignancy and higher risk categories" considered positive, sensitivity and specificity were 49% (95% CI, 40%-58%) and 95% (95% CI, 92%-97%), respectively. Sensitivity and specificity for the "Malignant" category considered positive for malignancy were 42% (95% CI, 33%-52%) and 97% (95% CI, 92%-99%), respectively. The pooled Area Under the Curve (AUC) ranged from 68% to 75% for each cut-off.
Conclusion
This meta-analysis underscores the PSC system's accuracy in reporting respiratory cytology. It highlights the diagnostic importance of the "Suspicious" and "Malignant" categories in identifying malignancy, and the utility of the "Atypical" category for initial screening. These findings support the PSC system's role in enhancing diagnostic accuracy and clinical decision-making in respiratory cytology.
DOI: 10.6084/m9.figshare.21855813.v1
title: Data of condensation spray flow

description: This is a dataset of condensation spray flow. It includes datasets of "measure temperature" and "measured droplet diameter and velocity."
DOI: 10.6084/m9.figshare.19699795.v1
title: panel_data.csv

description: Panel data for the paper "Hedging Commodities in Times of Distress: The Case of COVID-19".
DOI: 10.6084/m9.figshare.24572983.v1
title: Supplementary Material for: Clinical Features of Quail Egg Ingestion in Patients With Acquired Tolerance to Hen Eggs: A Case Series Study

description: Introduction Patients with hen’s egg allergy are often instructed to avoid consuming other avian eggs, such as quail eggs. However, it is unclear whether patients with an acquired tolerance to hen eggs continue to avoid consuming quail eggs. This study aimed to evaluate the clinical features of quail egg ingestion. Methods This prospective case series included children aged ≥1 year with hen’s egg allergy who were recruited between October 2019 and February 2021 in our hospital. We conducted an oral food challenge (OFC) with three boiled quail eggs to evaluate the clinical features of quail egg ingestion in patients with acquired tolerance to hen eggs. The primary outcome was a positive OFC after ingesting three quail eggs. Secondary outcomes were cross-antigenicity between hen and quail eggs observed through the skin prick test (SPT) and pattern of quail egg allergy, comprising the onset of reaction, and severity. The correlation between the diameters of the wheals with SPT in hen and quail eggs was evaluated using the Pearson product-moment correlation coefficient. Results A total of 62 patients underwent the quail egg OFC. The median (interquartile range) age of the participants was 3 (2-5) years. Thirty-three (53%) patients had a history of anaphylaxis due to hen eggs. The median total immunoglobulin E (IgE) level in patients who underwent the OFC with half a heated whole hen’s egg was 271 (98-593) IU/mL. The median specific IgE level in egg white and ovomucoid was 9.7 (3.2-21.5) and 4.4 (1.3-6.9) UA/mL, respectively. The quail egg OFC results revealed that none of the 59 patients who ate the three quail eggs completely had an allergic reaction. The SPT-positive and SPT-negative rates in raw and boiled hen and quail egg whites were both correlated. The diameters of wheals with SPT in raw hen and quail egg whites and yolks were positively correlated. Conclusion Patients with an acquired tolerance to hen eggs may not be required to avoid consuming quail eggs.
DOI: 10.6084/m9.figshare.23989410.v1
title: Estrogen prevents age-dependent beige adipogenesis failure through NAMPT-controlled ER stress pathway

description: Thermogenic beige adipocytes are recognized as potential therapeutic targets for combating metabolic diseases. However, the metabolic advantages they offer are compromised with aging. Here, we show that treating mice with estrogen (E2), a hormone that decreases with age can counteract the age-related decline in beige adipogenesis when exposed to cold temperature, while concurrently enhancing energy expenditure and improving glucose tolerance in mice. Mechanistically, we find that nicotinamide phosphoribosyl transferase (NAMPT) plays a pivotal role in facilitating the formation of E2-induced beige adipocytes, which subsequently suppresses the onset of age-related ER stress. Furthermore, we found that targeting NAMPT signaling, either genetically or pharmacologically, can restore the formation of beige adipocytes by increasing the number of perivascular adipocyte progenitor cells. Conversely, the absence of NAMPT signaling prevents this process. Together, our findings shed light on the mechanisms regulating the age-dependent impairment of beige adipocyte formation and underscore the E2-NAMPT-controlled ER stress pathway as a key regulator of this process.
DOI: 10.6084/m9.figshare.28005257.v1
title: Rice Meta Date

description: Temperature is a critical environmental factor affecting the growth and development of rice, especially under the backdrop of global climate change, where temperature fluctuations have become increasingly significant in influencing the growth cycle and development rate of rice. To comprehensively evaluate the impact of temperature changes on various growth stages of rice, this study conducted a meta-analysis by integrating data from multiple relevant studies, systematically analyzing the effect of temperature on the development rate across six growth cycles of rice. The results indicate that increased temperatures significantly accelerate the development rate of rice during all growth stages, with a general acceleration in growth speed at different developmental phases. The study further found that when the temperature ranges from 28℃to 32℃, the growing conditions for rice are most favorable, exhibiting the optimal development rate. This study provides scientific evidence for understanding how temperature changes affect rice growth and development and offers valuable references for rice cultivation management and climate adaptation strategies.