cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.14290187.v1
title: Depressive symptoms and chronotypes of elderly nursing home residentes: A case management study

description: ABSTRACT. Institutionalization potentiates the tendency for specific sleep disturbances which occur with aging, besides negative health consequences such as increased rate of depressive symptoms. Objective: To compare sleep profile and depressive symptoms in elderly nursing home residents, highlighting gender differences. Methods: A quantitative descriptive study of 29 elderly from two different nursing homes was conducted. A sociodemographics questionnaire, Sleep Diary, Morningness-Eveningness Questionnaire and the 15-item Geriatric Depression Scale were applied. Data were analyzed using descriptive statistics, Student’s t-test and the Mann-Whitney U-test. Results: The sample comprised individuals that were predominantly female (72%), aged 80-90 years (48%), widowed (66%) and low-educated (83%). The women were found to sleep and awake later than the men. Regarding chronotypes, the women were classified as evening types and men as intermediate/indifferent types. Most of the elderly exhibited symptoms of major depression (48%). Compared to men, women had more depressive symptoms in both dysthymia and major depression categories. Conclusion: No significant differences were evident on comparisons of sleep profile and depressive symptoms, but elderly with the intermediate chronotype scored lower on the depressive symptoms scale.
DOI: 10.6084/m9.figshare.14290190
title: Challenges in the diagnosis of dementia: insights from the United Kingdom-Brazil Dementia Workshop

description: ABSTRACT. In July 2019, a group of multidisciplinary dementia researchers from Brazil and the United Kingdom (UK) met in the city of Belo Horizonte, Minas Gerais, Brazil, to discuss and propose solutions to current challenges faced in the diagnosis, public perception and care of dementia. Here we summarize the outcomes from the workshop addressing challenges in diagnosis. Brazil faces a major problem in dementia underdiagnosis, particularly involving the population in an adverse socioeconomic context. There is poor availability of resources and specialists, and the knowledge of general practitioners and other healthcare professionals is far from satisfactory. Low education level is a further obstacle in diagnosing dementia, as the most commonly used screening tests are not designed to evaluate this population. Patients and their families must overcome the stigma of a diagnosis of dementia, which is still prevalent in Brazil and increases the burden of this condition. Whilst the UK has greater resources, dedicated memory services and a National Dementia Strategy plan, the National Health Service (NHS) has limited funding. Therefore, some challenges regarding diagnosis are common across both countries. The authors suggest possible solutions to confront these, with the goal of improving assessment and recognition of dementia and reducing misdiagnosis.
DOI: 10.6084/m9.figshare.14290192
title: Pharmacological interventions in corticobasal degeneration: a review

description: ABSTRACT. Corticobasal degeneration (CBD) is a sporadic tauopathy that presents with a varied combination of motor, cognitive, and behavioral features, making its diagnosis difficult. CBD has high morbidity and poor prognosis, with no effective therapy at present. We searched the PubMed/MEDLINE database for articles published from 1990 to 2019, using the keywords “corticobasal degeneration” AND “treatment.” The PRISMA method was adopted. Retrieved articles were characterized as having one of two methodological approaches: (1) studies aimed at primary tauopathy treatment and (2) symptomatic management. Review articles (based on CBD expert groups), case reports, case series, and pilot clinical trials were selected. Few attempts have been made to study drug options and drug efficacy in CBD systematically, and an effective treatment is not yet available. Treatment is symptomatic and based on similarity with other diseases due to the scarcity of studies specifically addressing CBD. CBD seems not to spark interest in more clinical trials for its low prevalence and reliability in clinical diagnosis.
DOI: 10.6084/m9.figshare.14290192.v1
title: Pharmacological interventions in corticobasal degeneration: a review

description: ABSTRACT. Corticobasal degeneration (CBD) is a sporadic tauopathy that presents with a varied combination of motor, cognitive, and behavioral features, making its diagnosis difficult. CBD has high morbidity and poor prognosis, with no effective therapy at present. We searched the PubMed/MEDLINE database for articles published from 1990 to 2019, using the keywords “corticobasal degeneration” AND “treatment.” The PRISMA method was adopted. Retrieved articles were characterized as having one of two methodological approaches: (1) studies aimed at primary tauopathy treatment and (2) symptomatic management. Review articles (based on CBD expert groups), case reports, case series, and pilot clinical trials were selected. Few attempts have been made to study drug options and drug efficacy in CBD systematically, and an effective treatment is not yet available. Treatment is symptomatic and based on similarity with other diseases due to the scarcity of studies specifically addressing CBD. CBD seems not to spark interest in more clinical trials for its low prevalence and reliability in clinical diagnosis.
DOI: 10.6084/m9.figshare.14290195
title: A closer look at the epidemiology of schizophrenia and common mental disorders in Brazil

description: ABSTRACT. Schizophrenia and common mental disorders are noteworthy social and economic concern worldwide. Epidemiologic studies on the impact of specific mental disorders in emerging countries are scarce. Objectives: We aimed to characterize the demographic, social, and economic burden of schizophrenia and common mental disorders patients in the health system in Brazil. Methods: Data on these conditions in Brazil between 2008 and 2019 were collected through the website of the Departamento de Informática do Sistema Único de Saúde (Information Technology Department of the Unified Health System - DATASUS) maintained by the Brazilian Ministry of Health. Mean annual hospital admissions were 154,009.67, and cumulative incidence of 77.44 admissions per 100,000 inhabitants. Results: Average annual hospital expenses were US$ 67,216,056.04, with an average admission cost of US$ 432.58. The most affected age groups were older adults albeit younger individuals showed a trend towards increase of occurrences in recent years. There were a higher number of admissions in men compared to women. Conclusions: We consider the results obtained important to assist in evaluating and guiding public policies regarding the prevention and treatment in health systems.
DOI: 10.6084/m9.figshare.14290195.v1
title: A closer look at the epidemiology of schizophrenia and common mental disorders in Brazil

description: ABSTRACT. Schizophrenia and common mental disorders are noteworthy social and economic concern worldwide. Epidemiologic studies on the impact of specific mental disorders in emerging countries are scarce. Objectives: We aimed to characterize the demographic, social, and economic burden of schizophrenia and common mental disorders patients in the health system in Brazil. Methods: Data on these conditions in Brazil between 2008 and 2019 were collected through the website of the Departamento de Informática do Sistema Único de Saúde (Information Technology Department of the Unified Health System - DATASUS) maintained by the Brazilian Ministry of Health. Mean annual hospital admissions were 154,009.67, and cumulative incidence of 77.44 admissions per 100,000 inhabitants. Results: Average annual hospital expenses were US$ 67,216,056.04, with an average admission cost of US$ 432.58. The most affected age groups were older adults albeit younger individuals showed a trend towards increase of occurrences in recent years. There were a higher number of admissions in men compared to women. Conclusions: We consider the results obtained important to assist in evaluating and guiding public policies regarding the prevention and treatment in health systems.
DOI: 10.6084/m9.figshare.14290198
title: Speech in the foreign accent syndrome: differential diagnosis between organic and functional cases

description: ABSTRACT. Foreign accent syndrome (FAS) is an extremely rare disorder, with 112 cases described until 2019. We compare two cases of the foreign accent syndrome in native speakers of Brazilian Portuguese in its classic form (FAS) and psychiatric variant (FALS). Two cases were analyzed: (1) a right-handed, 69-year-old man, with a prior history of stroke, and (2) a right-handed, 43-year-old woman, diagnosed with schizophrenia. They were evaluate for language and speech, including the speech intelligibility. Both patients had speech impairments complaints, similar to a new accent, without previous exposure to a foreign language. However, the onset of the speech disorder was sudden in case 1 and insidious and with transient events in case 2, with speech intelligibility scores of 95.5 and 55.3% respectively. Besides neurologic impairment, the clinical presentation of FALS was extremely severe and differed to that expected in FAS cases, in which speech intelligibility is preserved.
DOI: 10.6084/m9.figshare.14290199.v1
title: Phineas Gage's great legacy

description: ABSTRACT. The case of Phineas Gage is an integral part of medical folklore. His accident still causes astonishment and curiosity and can be considered as the case that most influenced and contributed to the nineteenth century's neuropsychiatric discussion on the mind-brain relationship and brain topography. It was perhaps the first case to suggest the role of brain areas in determining personality and which specific parts of the brain, when affected, can induce specific mental changes. In addition, his case contributed to the emergence of the scientific approaches that would later culminate in psychosurgery. Gage is a fixed element in the studies of neurology, psychology, and neuroscience, having been solidified as one of the greatest medical curiosities of all time, deserving its prominence.
DOI: 10.6084/m9.figshare.14290198.v1
title: Speech in the foreign accent syndrome: differential diagnosis between organic and functional cases

description: ABSTRACT. Foreign accent syndrome (FAS) is an extremely rare disorder, with 112 cases described until 2019. We compare two cases of the foreign accent syndrome in native speakers of Brazilian Portuguese in its classic form (FAS) and psychiatric variant (FALS). Two cases were analyzed: (1) a right-handed, 69-year-old man, with a prior history of stroke, and (2) a right-handed, 43-year-old woman, diagnosed with schizophrenia. They were evaluate for language and speech, including the speech intelligibility. Both patients had speech impairments complaints, similar to a new accent, without previous exposure to a foreign language. However, the onset of the speech disorder was sudden in case 1 and insidious and with transient events in case 2, with speech intelligibility scores of 95.5 and 55.3% respectively. Besides neurologic impairment, the clinical presentation of FALS was extremely severe and differed to that expected in FAS cases, in which speech intelligibility is preserved.
DOI: 10.6084/m9.figshare.14290199
title: Phineas Gage's great legacy

description: ABSTRACT. The case of Phineas Gage is an integral part of medical folklore. His accident still causes astonishment and curiosity and can be considered as the case that most influenced and contributed to the nineteenth century's neuropsychiatric discussion on the mind-brain relationship and brain topography. It was perhaps the first case to suggest the role of brain areas in determining personality and which specific parts of the brain, when affected, can induce specific mental changes. In addition, his case contributed to the emergence of the scientific approaches that would later culminate in psychosurgery. Gage is a fixed element in the studies of neurology, psychology, and neuroscience, having been solidified as one of the greatest medical curiosities of all time, deserving its prominence.
DOI: 10.6084/m9.figshare.14290202
title: Practices of caregivers when evaluating the risk of falls in the admission of older adults to nursing homes

description: ABSTRACT. Falls are a complex problem for the older population residing in nursing homes. Despite recommendations, many difficulties remain in the evaluation of and systematic information on fall risk factors. Objectives: To build and validate the Scale for Practices of Identification of and Information on Fall Risk Factors in the Admission of Older Adults; to describe the practices of professionals in identifying and providing information on fall risk factors in the admission of older adults; and to associate these practices with the training, experience, and age of the caretakers. Methods: This is a methodological study. Based on a literature review, we analyzed the contexts, consulted specialists, selected indicators, and designed the scale, which was evaluated by experts. The process included a pre-test, reformulation, application, and validation. Results: The response rate was 65.52%. The validated scale has 13 items and 2 dimensions: risk factor evaluation practices and information practices; it presents good psychometric properties (α=0.913) to evaluate the risk of falls in the admission of older adults. Conclusions: Caregivers who received training during professional activities had better practices as to the provision of information to older adults about the risk of falls. The risk associated with gait and balance changes is more significant compared to the cognitive state.
DOI: 10.6084/m9.figshare.14290207
title: Effects of a multimodal exercise program on the functional capacity of Parkinson's disease patients considering disease severity and gender

description: The purpose of this study was to investigate the effects of a multimodal exercise program (MEP) on the functional capacity of patients with Parkinson's disease (PD) according to disease severity and gender. Fourteen patients with PD participated in the study and were distributed into groups according to 1) stage of disease and 2) gender. Functional capacity was evaluated before and after 6 months of intervention. The overall PD patient group improved their coordination and strength. Men and women improved in strength performance after exercise. Men also improved on coordination. For severity of disease, the unilateral group improved in strength, while the bilateral group improved in strength, balance, coordination and the UPDRS-functional score. In conclusion, a MEP is efficient in improving components of functional capacity in patients with PD, especially in strength. Gender may be considered in the exercise program. Individuals in the bilateral disease group appeared to benefit more from exercise.
DOI: 10.6084/m9.figshare.14290202.v1
title: Practices of caregivers when evaluating the risk of falls in the admission of older adults to nursing homes

description: ABSTRACT. Falls are a complex problem for the older population residing in nursing homes. Despite recommendations, many difficulties remain in the evaluation of and systematic information on fall risk factors. Objectives: To build and validate the Scale for Practices of Identification of and Information on Fall Risk Factors in the Admission of Older Adults; to describe the practices of professionals in identifying and providing information on fall risk factors in the admission of older adults; and to associate these practices with the training, experience, and age of the caretakers. Methods: This is a methodological study. Based on a literature review, we analyzed the contexts, consulted specialists, selected indicators, and designed the scale, which was evaluated by experts. The process included a pre-test, reformulation, application, and validation. Results: The response rate was 65.52%. The validated scale has 13 items and 2 dimensions: risk factor evaluation practices and information practices; it presents good psychometric properties (α=0.913) to evaluate the risk of falls in the admission of older adults. Conclusions: Caregivers who received training during professional activities had better practices as to the provision of information to older adults about the risk of falls. The risk associated with gait and balance changes is more significant compared to the cognitive state.
DOI: 10.6084/m9.figshare.14290204
title: Cerebral toxoplasmosis and alcohol abuse in AIDS: dementia with multiple etiologies

description: ABSTRACT Major neurocognitive disorder due to multiple etiologies, or dementia due to multiple etiologies (DME), is a term coined by the Diagnostic and Statistical Manual of Mental Disorders to refer to complex cases when multiple pathologies, such as Alzheimer's disease, Lewy Bodies, human immunodeficiency virus (HIV), vascular-related brain damage or frontotemporal lobar degeneration, are identified as contributing to neurocognitive impairment and/or behavioral alterations, based on patient's neuroimaging tests, laboratorial exams, associated symptomatology and medical history. In this study, we report the case of a 63-year-old male patient who presented with parkinsonism symptoms, aphasia and cognitive impairment on multiple domains after cerebral toxoplasmosis related to acquired immunodeficiency syndrome, vascular damage and a history of alcohol abuse. We discuss the neurocognitive and neurobehavioral variables that characterized this diagnosis, as well as the importance of the differential diagnosis of DME on the field of neuropsychology of aging and, especially, for individuals living with HIV infection.
DOI: 10.6084/m9.figshare.14290204.v1
title: Cerebral toxoplasmosis and alcohol abuse in AIDS: dementia with multiple etiologies

description: ABSTRACT Major neurocognitive disorder due to multiple etiologies, or dementia due to multiple etiologies (DME), is a term coined by the Diagnostic and Statistical Manual of Mental Disorders to refer to complex cases when multiple pathologies, such as Alzheimer's disease, Lewy Bodies, human immunodeficiency virus (HIV), vascular-related brain damage or frontotemporal lobar degeneration, are identified as contributing to neurocognitive impairment and/or behavioral alterations, based on patient's neuroimaging tests, laboratorial exams, associated symptomatology and medical history. In this study, we report the case of a 63-year-old male patient who presented with parkinsonism symptoms, aphasia and cognitive impairment on multiple domains after cerebral toxoplasmosis related to acquired immunodeficiency syndrome, vascular damage and a history of alcohol abuse. We discuss the neurocognitive and neurobehavioral variables that characterized this diagnosis, as well as the importance of the differential diagnosis of DME on the field of neuropsychology of aging and, especially, for individuals living with HIV infection.
DOI: 10.6084/m9.figshare.14290207.v1
title: Effects of a multimodal exercise program on the functional capacity of Parkinson's disease patients considering disease severity and gender

description: The purpose of this study was to investigate the effects of a multimodal exercise program (MEP) on the functional capacity of patients with Parkinson's disease (PD) according to disease severity and gender. Fourteen patients with PD participated in the study and were distributed into groups according to 1) stage of disease and 2) gender. Functional capacity was evaluated before and after 6 months of intervention. The overall PD patient group improved their coordination and strength. Men and women improved in strength performance after exercise. Men also improved on coordination. For severity of disease, the unilateral group improved in strength, while the bilateral group improved in strength, balance, coordination and the UPDRS-functional score. In conclusion, a MEP is efficient in improving components of functional capacity in patients with PD, especially in strength. Gender may be considered in the exercise program. Individuals in the bilateral disease group appeared to benefit more from exercise.
DOI: 10.6084/m9.figshare.14290210
title: Strength and sources of self-efficacy beliefs by physical education student teachers

description: In the teaching domain, self-efficacy (SE) is related to teachers' judgment about their own ability to achieve learning outcomes and student engagement. SE is formed by four sources of information: mastery experiences, vicarious experiences, social persuasion, and psychophysiological states. We measured and analyzed SE and its sources for teaching physical education. Student teachers (n = 114) from three universities responded to two Likert scales - Physical Education Teacher Self-Efficacy Scale and Teacher Self-Efficacy Scale Sources - and a social demographic questionnaire. SE for teaching was classified as moderate, and vicarious experiences and social persuasion were the main sources of information. Results were discussed for future researches related to teaching practices in undergraduate programs as well as in-service teacher training.
DOI: 10.6084/m9.figshare.14290208
title: Improved exercise capacity in the heat followed by coconut water consumption

description: The aim of the present study was to assess the effects of prior ingestion of coconut water on fluid retention and exercise capacity in the heat as well as signs of gastrointestinal distress. Eight physically active men were recruited (age 23 ± 3 years, height 176 ± 6 cm, body mass 78 ± 7 kg) and performed three exercise capacity trials on a cycle ergometer in the heat (34 ± 1°C) after the ingestion of one of the following drinks: a) plain water (PW), b) flavored drink (FD), and c) coconut water (CW). Ingestion of CWresulted in a longer time to exhaustion (p=0.029). Likewise, participants achieved a higher heart rate in the CW session when compared to the other trials (PW 183 ± 5 bpm, FD 184 ± 8 bpm, and CW 189 ± 8 bpm, p&lt;0.05) and a reduced urine output after the coconut water ingestion (PW 214 ± 85 ml, FD 267 ± 90 ml, and CW 161 ± 73 ml, p&lt;0.05) indicating a higher fluid retention of coconut water in comparison to plain water and the flavored drink. These results demonstrate that previous ingestion of coconut water improves exercise capacity in the heat and provide a reduced urine output in comparison to plain water and flavored drink. Also there is no evidence for GI distress.
DOI: 10.6084/m9.figshare.14290208.v1
title: Improved exercise capacity in the heat followed by coconut water consumption

description: The aim of the present study was to assess the effects of prior ingestion of coconut water on fluid retention and exercise capacity in the heat as well as signs of gastrointestinal distress. Eight physically active men were recruited (age 23 ± 3 years, height 176 ± 6 cm, body mass 78 ± 7 kg) and performed three exercise capacity trials on a cycle ergometer in the heat (34 ± 1°C) after the ingestion of one of the following drinks: a) plain water (PW), b) flavored drink (FD), and c) coconut water (CW). Ingestion of CWresulted in a longer time to exhaustion (p=0.029). Likewise, participants achieved a higher heart rate in the CW session when compared to the other trials (PW 183 ± 5 bpm, FD 184 ± 8 bpm, and CW 189 ± 8 bpm, p&lt;0.05) and a reduced urine output after the coconut water ingestion (PW 214 ± 85 ml, FD 267 ± 90 ml, and CW 161 ± 73 ml, p&lt;0.05) indicating a higher fluid retention of coconut water in comparison to plain water and the flavored drink. These results demonstrate that previous ingestion of coconut water improves exercise capacity in the heat and provide a reduced urine output in comparison to plain water and flavored drink. Also there is no evidence for GI distress.