cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.29313164
title: Supplementary Material for: Repeat Intravitreal Bevacizumab in a Very Low Birth Weight Infant with Recurrent ROP: 3-Year Follow-Up and Literature Review

description: Purpose: Low gestational birth weight is associated with increased incidence of Retinopathy of Prematurity (ROP). In recent years, intravitreal injection of anti-vascular endothelial growth factor (VEGF) has become more prevalent for ROP. Despite the demonstrated effectiveness following anti-VEGF injection, recurrence of ROP has been reported. A standardized treatment protocol for recurrent ROP following anti-VEGF monotherapy is still lacking, particularly for extremely low birthweight infants. This study reviews possible treatments for recurrent ROP and associated challenges.
Case Report: We report a very low birth weight infant (500g) with a recurrence of ROP after the initial intravitreal Bevacizumab (IVB) injection, who was successfully treated with a repeat injection at a later date. No retinal detachment or no recurrence was observed after a long term follow up of 36 months. 
Conclusion: This case report highlights the complexity of managing ROP, particularly for recurrent ROP in very low birth weight infants. Premature infants with extremely low birth weight may benefit from a repeat injection of anti-VEGF after the initial IVB to treat the recurrence.
DOI: 10.6084/m9.figshare.29313164.v1
title: Supplementary Material for: Repeat Intravitreal Bevacizumab in a Very Low Birth Weight Infant with Recurrent ROP: 3-Year Follow-Up and Literature Review

description: Purpose: Low gestational birth weight is associated with increased incidence of Retinopathy of Prematurity (ROP). In recent years, intravitreal injection of anti-vascular endothelial growth factor (VEGF) has become more prevalent for ROP. Despite the demonstrated effectiveness following anti-VEGF injection, recurrence of ROP has been reported. A standardized treatment protocol for recurrent ROP following anti-VEGF monotherapy is still lacking, particularly for extremely low birthweight infants. This study reviews possible treatments for recurrent ROP and associated challenges.
Case Report: We report a very low birth weight infant (500g) with a recurrence of ROP after the initial intravitreal Bevacizumab (IVB) injection, who was successfully treated with a repeat injection at a later date. No retinal detachment or no recurrence was observed after a long term follow up of 36 months. 
Conclusion: This case report highlights the complexity of managing ROP, particularly for recurrent ROP in very low birth weight infants. Premature infants with extremely low birth weight may benefit from a repeat injection of anti-VEGF after the initial IVB to treat the recurrence.
DOI: 10.6084/m9.figshare.29313167
title: Supplementary Material for: New insights into the interaction of sugarcane cystatin (CaneCPI-5) with the surface of hydroxyapatite through molecular dynamics simulations

description: Introduction: This study conducted a molecular dynamics simulation to elucidate the interactions in silico between a sugarcane cystatin (CaneCPI-5) and hydroxyapatite, aiming to deepen the understanding of its potential role in modulating the dental enamel demineralization process. Methods: The CaneCPI-5 protein structure was modeled using homology with SWISS-MODEL, based on the multicystatin template PDB-ID 4LZI. Molecular dynamics simulations were conducted with the protein positioned randomly in a box containing a hydroxyapatite surface (001 face). Molecular dynamics simulations were then carried out for 500 ns with control of temperature and pressure using the GROMACS package. The free energy of interaction between CaneCPI-5 and the hydroxyapatite surface was calculated using the MM/GBSA method based on trajectory frames. Results: For several initial orientations, the protein rapidly migrated to anchor to the surface, ensuring minimal distance between its amino acid residues and the surface. Most residues interacting with the surface phosphates were positively charged. Arginine 81, alanine 105 and arginine 107 were found to be key residues. During the simulations, similar values were observed for all orientations in terms of root-mean-square deviation, radius of gyration, and root mean square fluctuation. The free energy calculation showed strong protein-hydroxyapatite interactions, except for one of the initial orientations. Conclusion: This study demonstrates that CaneCPI-5 has affinity for hydroxyapatite surfaces, with positively charged residues, particularly arginine. The stable binding observed throughout the simulations suggests that this protein may contribute to mechanisms that influence the integrity of dental enamel in demineralizing conditions.
DOI: 10.6084/m9.figshare.29313167.v1
title: Supplementary Material for: New insights into the interaction of sugarcane cystatin (CaneCPI-5) with the surface of hydroxyapatite through molecular dynamics simulations

description: Introduction: This study conducted a molecular dynamics simulation to elucidate the interactions in silico between a sugarcane cystatin (CaneCPI-5) and hydroxyapatite, aiming to deepen the understanding of its potential role in modulating the dental enamel demineralization process. Methods: The CaneCPI-5 protein structure was modeled using homology with SWISS-MODEL, based on the multicystatin template PDB-ID 4LZI. Molecular dynamics simulations were conducted with the protein positioned randomly in a box containing a hydroxyapatite surface (001 face). Molecular dynamics simulations were then carried out for 500 ns with control of temperature and pressure using the GROMACS package. The free energy of interaction between CaneCPI-5 and the hydroxyapatite surface was calculated using the MM/GBSA method based on trajectory frames. Results: For several initial orientations, the protein rapidly migrated to anchor to the surface, ensuring minimal distance between its amino acid residues and the surface. Most residues interacting with the surface phosphates were positively charged. Arginine 81, alanine 105 and arginine 107 were found to be key residues. During the simulations, similar values were observed for all orientations in terms of root-mean-square deviation, radius of gyration, and root mean square fluctuation. The free energy calculation showed strong protein-hydroxyapatite interactions, except for one of the initial orientations. Conclusion: This study demonstrates that CaneCPI-5 has affinity for hydroxyapatite surfaces, with positively charged residues, particularly arginine. The stable binding observed throughout the simulations suggests that this protein may contribute to mechanisms that influence the integrity of dental enamel in demineralizing conditions.
DOI: 10.6084/m9.figshare.29313170
title: Supplementary Material for: Impact of Living in a Mountain Environment on Health and Mortality: Insights from the Alpine Population in Northern Italy

description: Introduction: Residing at moderate altitudes has been associated with various health benefits also affecting mortality risk. This study investigates life expectancy and disease-specific mortality rates among populations in the Italian Alps and in northern Italian lowland regions. Additionally, cardiometabolic health and serum metabolite concentrations of residents in an Alpine province across three distinct elevation zones (&lt;1,000 m, 1,000-1,500 m, and &gt;1,500 m above sea level) are studied. Methods: Data on life expectancy and mortality rate (per ten thousand) were retrieved from the ISTAT database for 6 provinces located in the Italian Alps and 6 provinces at sea level near the Alps. Using cross-sectional data from a sub-sample of the Cooperative Health Research in South Tyrol (CHRIS) study (n=6,292), we fitted multivariable adjusted logistic regression models to investigate associations between altitude and cardiometabolic health, determined by the Cumulative Illness Rating Scale. Moreover, associations between altitude and 175 serum metabolites were evaluated through linear regression models (n=1,447). Results: Population size and sex distribution were similar between provinces (p&gt;0.485). Life expectancy at 65 years differed between areas (20.8±0.4 vs 20.1±0.3, for Alps vs sea-level, respectively, p=0.026). Mortality rate for diseases of the circulatory system was lower in the Alps than at sea-level (35.3±5.7 vs. 44.5±6.8, respectively, p=0.026). No statistically significant differences were found for mortality (Alps vs. sea-level) from all causes (108.1±15.7 vs. 126.1±15.5, p=0.065), cerebrovascular diseases (8.4±2.5 vs. 12.6±3.1, p=0.065), endocrine, nutritional and metabolic diseases (3.6±1.0 vs. 5.0±1.0, p=0.065), neoplasms (31.1±4.7 vs. 34.3±2.4 p=0.394) and diseases of the respiratory system (8.3±1.7 vs. 8.8±1.7, p=0.589). In the CHRIS study sample, living at moderate vs. low altitude level was associated with lower odds of mild to severe conditions in the hypertension (OR:0.77; 95%CI: 0.62-0.96) and endocrine-metabolic domain (OR:0.77, 95%CI: 0.61-0.97). No differences in blood serum metabolic profiles were observed between people living at different altitude levels. Conclusions: Living in the Italian Alps seems to have a positive effect on life expectancy and mortality from certain diseases compared to living at sea level in northern Italy. Furthermore, living at moderate altitude conferred some cardiometabolic health benefits in the CHRIS study population, even after corrections for confounding factors. The metabolite profile in a sub-sample did, however, not reveal any significant differences between altitude levels.
DOI: 10.6084/m9.figshare.29313170.v1
title: Supplementary Material for: Impact of Living in a Mountain Environment on Health and Mortality: Insights from the Alpine Population in Northern Italy

description: Introduction: Residing at moderate altitudes has been associated with various health benefits also affecting mortality risk. This study investigates life expectancy and disease-specific mortality rates among populations in the Italian Alps and in northern Italian lowland regions. Additionally, cardiometabolic health and serum metabolite concentrations of residents in an Alpine province across three distinct elevation zones (&lt;1,000 m, 1,000-1,500 m, and &gt;1,500 m above sea level) are studied. Methods: Data on life expectancy and mortality rate (per ten thousand) were retrieved from the ISTAT database for 6 provinces located in the Italian Alps and 6 provinces at sea level near the Alps. Using cross-sectional data from a sub-sample of the Cooperative Health Research in South Tyrol (CHRIS) study (n=6,292), we fitted multivariable adjusted logistic regression models to investigate associations between altitude and cardiometabolic health, determined by the Cumulative Illness Rating Scale. Moreover, associations between altitude and 175 serum metabolites were evaluated through linear regression models (n=1,447). Results: Population size and sex distribution were similar between provinces (p&gt;0.485). Life expectancy at 65 years differed between areas (20.8±0.4 vs 20.1±0.3, for Alps vs sea-level, respectively, p=0.026). Mortality rate for diseases of the circulatory system was lower in the Alps than at sea-level (35.3±5.7 vs. 44.5±6.8, respectively, p=0.026). No statistically significant differences were found for mortality (Alps vs. sea-level) from all causes (108.1±15.7 vs. 126.1±15.5, p=0.065), cerebrovascular diseases (8.4±2.5 vs. 12.6±3.1, p=0.065), endocrine, nutritional and metabolic diseases (3.6±1.0 vs. 5.0±1.0, p=0.065), neoplasms (31.1±4.7 vs. 34.3±2.4 p=0.394) and diseases of the respiratory system (8.3±1.7 vs. 8.8±1.7, p=0.589). In the CHRIS study sample, living at moderate vs. low altitude level was associated with lower odds of mild to severe conditions in the hypertension (OR:0.77; 95%CI: 0.62-0.96) and endocrine-metabolic domain (OR:0.77, 95%CI: 0.61-0.97). No differences in blood serum metabolic profiles were observed between people living at different altitude levels. Conclusions: Living in the Italian Alps seems to have a positive effect on life expectancy and mortality from certain diseases compared to living at sea level in northern Italy. Furthermore, living at moderate altitude conferred some cardiometabolic health benefits in the CHRIS study population, even after corrections for confounding factors. The metabolite profile in a sub-sample did, however, not reveal any significant differences between altitude levels.
DOI: 10.5281/zenodo.15655345
title: Kohren-Salis Adler-Apotheke

description: Historical questionnaire/s 1924/1948 and index cards, partly selected enclosures regarding the history of a German pharmacy, catalogued via Kalliope portal (Historischer Fragebogen 1924/1948 und Karteikarten, ggf. gemeinfreie Anlagen zur Apothekengeschichte; als Katalog dient das Nachlassportal Kalliope): https://kalliope-verbund.info/DE-611-BF-70963 [Funktion: Im Findbuch anzeigen]Please note: The Kalliope catalogue entry might indicate related material in the archival folder which cannot be published due to copyright or other legal restrictions (NB: Das Katalogisat bei Kalliope kann auch auf Materialien - teils erheblichen Umfangs - verweisen, die aus archiv- oder urheberrechtlichen Gründen nicht veröffentlicht werden dürfen).
DOI: 10.5281/zenodo.15655346
title: Kohren-Salis Adler-Apotheke

description: Historical questionnaire/s 1924/1948 and index cards, partly selected enclosures regarding the history of a German pharmacy, catalogued via Kalliope portal (Historischer Fragebogen 1924/1948 und Karteikarten, ggf. gemeinfreie Anlagen zur Apothekengeschichte; als Katalog dient das Nachlassportal Kalliope): https://kalliope-verbund.info/DE-611-BF-70963 [Funktion: Im Findbuch anzeigen]Please note: The Kalliope catalogue entry might indicate related material in the archival folder which cannot be published due to copyright or other legal restrictions (NB: Das Katalogisat bei Kalliope kann auch auf Materialien - teils erheblichen Umfangs - verweisen, die aus archiv- oder urheberrechtlichen Gründen nicht veröffentlicht werden dürfen).
DOI: 10.60756/lnec-tasw25g398
title: Shake-table testing of a full-scale URM cavity-wall building developing a two-way out-of-plane bending collapse mechanism (LNEC-BUILD-1)

description: The dataset contains acceleration and displacement measurements from a shake-table test on a full-scale single-storey URM building, built with cavity walls and without any seismic-proof detailing. These tests complement earlier experiments on a full-scale two-storey building specimen simulating the end unit of a typical Dutch terraced house. Specifically, the new test building represents the upper part of the original building, including its second storey and the roof. The test structure was subjected to a series of incremental dynamic tests up to the collapse of the building. The test sequence included excitations under combined horizontal and vertical floor motions. The experiment was terminated with the development of a two-way out-of-plane bending collapse mechanism in one of the load-bearing walls of the building.

The shake-table tests were conducted in 2017 at the National Laboratory for Civil Engineering (LNEC) facilities in Lisbon, Portugal. They were part of the EUCENTRE Foundation project 'Study of the vulnerability of masonry buildings in Groningen', within the research framework programme on hazard and risk of induced seismicity in the Groningen province, sponsored by the Nederlandse Aardolie Maatschappij BV (NAM). The project was carried out in collaboration with the research group of Masonry Structures from the University of Pavia in Italy.
DOI: 10.5281/zenodo.15655331
title: Supplementary Table 1. Quality assessment based on the AMSTAR-2 criteria

description: Supplementary Table 1. Quality assessment based on the AMSTAR-2 criteria
DOI: 10.5281/zenodo.15655332
title: Supplementary Table 1. Quality assessment based on the AMSTAR-2 criteria

description: Supplementary Table 1. Quality assessment based on the AMSTAR-2 criteria
DOI: 10.60756/lnec-dtv58z357
title: Shaking table testing of selectively retrofitted reinforced concrete walls

description: A number of reinforced concrete wall specimens were tested under dynamic conditions on the shaking-table at LNEC (Lisbon). The main objective of this experimental programme was to assess the effectiveness of selective intervention techniques for repair and strengthening of reinforced concrete walls. The models were tested up to collapse using both artificial and natural accelerograms.
DOI: 10.17632/bh3rjk62nd.1
title: Promotional Media for Sustainable Heritage Tourism: A Case Study of Kayutangan Icon in Malang City, Indonesia

description: Kayutangan Heritage is a historical area that is an icon of Malang City but is not yet widely known as a leading tourist destination. This study aims to design video content as a promotional media that can increase tourist interest in the area. The method used is Design Thinking through five stages: empathize, define, ideate, prototype, and test. Data were obtained through literature studies, observations, interviews, and questionnaires. The result is a video content that emphasizes the historical side, aesthetic visuals, and emotional approaches, which are expected to attract tourists' attention and strengthen Kayutangan's image as a city icon.
DOI: 10.15468/dl.ehqz35
title: Occurrence Download

description: A dataset containing 1183 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is China",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Buteo refectus Portenko, 1935"
 ]
}

 The dataset includes 1183 records from 6 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0042544-250525065834625/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.17632/rm8t8kmhpj.1
title: Motorbike Accident Severity Analysis Dataset

description: Summary of Motorbike Accident Severity Analysis Dataset Rules:

1. Severe Accident:
 Young students (14–29) with low education, minimal riding experience, long daily travel, who frequently talk and smoke while riding, do not wear helmets, inherit their bike, lack a driving license, ride old bikes on highways under poor road and weather conditions at night with high traffic, overspeed, consume alcohol, overtake vehicles, and ride in no-light conditions.

2. No Accident:
 Middle-aged employees (30–49) with higher education, experienced riders, short daily travel, who neither talk nor smoke while riding, wear helmets, own their bikes, have valid licenses, ride new bikes on dry rural roads during clear weather in daylight with low traffic, stay within speed limits, do not drink alcohol or overtake.

3. Moderate Accident:
 Older riders (50–74) who are educated or in other occupations, with moderate riding experience and daily travel distance, who often talk and sometimes smoke while riding, do not wear helmets, inherit their bikes, may or may not have a license, ride median-old bikes on highways with dry or wet roads in clear or rainy weather at various times of day, moderate traffic density, overspeed, possible alcohol consumption, possible overtaking, and varying road light conditions.
DOI: 10.17632/t3dbj86sjx.1
title: A computational workflow for assessing drug effects on temporal signaling dynamics reveals robustness in stimulus-specific NFκB signaling

description: simulation data for the paper "A computational workflow for assessing drug effects on temporal signaling dynamics reveals robustness in stimulus-specific NFκB signaling".
DOI: 10.15468/dl.pf2bf9
title: Occurrence Download

description: A dataset containing 13010 records in GBIF matching the query:
SELECT
 kingdom,
 kingdomkey,
 phylum,
 phylumkey,
 class,
 classkey,
 "order",
 orderkey,
 family,
 familykey,
 genus,
 genuskey,
 species,
 specieskey,
 "year",
 IF(ISNULL(kingdomkey), NULL, SUM(COUNT(*)) OVER (
 PARTITION BY kingdomkey, "year")) kingdomcount,
 IF(ISNULL(phylumkey), NULL, SUM(COUNT(*)) OVER (
 PARTITION BY phylumkey, "year")) phylumcount,
 IF(ISNULL(classkey), NULL, SUM(COUNT(*)) OVER (
 PARTITION BY classkey, "year")) classcount,
 IF(ISNULL(orderkey), NULL, SUM(COUNT(*)) OVER (
 PARTITION BY orderkey, "year")) ordercount,
 IF(ISNULL(familykey), NULL, SUM(COUNT(*)) OVER (
 PARTITION BY familykey, "year")) familycount,
 IF(ISNULL(genuskey), NULL, SUM(COUNT(*)) OVER (
 PARTITION BY genuskey, "year")) genuscount,
 COUNT(*) occurrences,
 MIN(GBIF_TEMPORALUNCERTAINTY(eventdate, eventtime)) mintemporaluncertainty,
 MIN(COALESCE(coordinateuncertaintyinmeters, 1000)) mincoordinateuncertaintyinmeters
FROM
 occurrence
WHERE
 occurrence.countrycode = 'VU'
 AND occurrence.occurrencestatus = 'PRESENT'
 AND (occurrence."year" &gt;= 2000 AND occurrence."year" &lt;= 2025)
 AND occurrence.hasgeospatialissues = FALSE
 AND NOT GBIF_STRINGARRAYCONTAINS(occurrence.issue, 'TAXON_MATCH_FUZZY', TRUE)
 AND (occurrence.distancefromcentroidinmeters &gt;= 2000.0 OR occurrence.distancefromcentroidinmeters IS NULL)
 AND NOT occurrence.basisofrecord IN ('FOSSIL_SPECIMEN', 'LIVING_SPECIMEN')
 AND (occurrence.specieskey IS NOT NULL AND occurrence."year" IS NOT NULL)
GROUP BY
 occurrence.kingdom,
 occurrence.kingdomkey,
 occurrence.phylum,
 occurrence.phylumkey,
 occurrence.class,
 occurrence.classkey,
 occurrence."order",
 occurrence.orderkey,
 occurrence.family,
 occurrence.familykey,
 occurrence.genus,
 occurrence.genuskey,
 occurrence.species,
 occurrence.specieskey,
 occurrence."year"

 The dataset's 13010 records were derived from 162 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0042527-250525065834625/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.18712/nsd-nsd3211-v1
title: NOKUT National Student Survey 2022, institutions

description: The National Student Survey is an annual survey directed at university and college students, conducted by the Norwegian Agency for Quality Assurance in Education (NOKUT) on behalf of the Ministry of Education. The survey asks students about their views on various aspects related to study quality, including teaching, guidance, learning environment, learning outcomes, and other important topics.

The purpose of the survey is to provide a more comprehensive information base for individuals considering a study program and to contribute to quality development efforts at Norwegian universities and colleges. The results are published on a dedicated web portal and distributed through various reports. NOKUT also shares anonymized data with educational institutions and other relevant stakeholders to enable them to conduct their own analyses. Additionally, the data is made available for research through Sikt. 

Nearly 35,000 students responded to the survey in 2022. Just under 7,000 of these were third-year students participating in a pilot for distributing the survey to third-year students. The survey covers study programs at bachelor's and master's levels offered in Norway that last at least three semesters. This includes regular bachelor's and master's studies as well as 4-, 5-, and 6-year professional programs such as teacher education, civil engineering, medicine, veterinary studies, and similar fields.

The NOKUT National Student Survey 2022 consists of four data files. This file contains information on the institutions.