cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17632/g2pbwnww8w.2
title: Spatial molecular anatomy of germ layers in the gastrulating Cynomolgus monkey embryo-Supplemental Materials

description: During mammalian embryogenesis, spatial regulation of gene expression and cell signaling are functionally coupled with lineage specification, patterning of tissue progenitors and germ layer morphogenesis. While the mouse model has been instrumental for understanding mammalian development, comparatively little is known about human and non-human primate gastrulation due to the restriction of both technical and ethical issues. Here, we present a spatial and temporal survey of the molecular dynamics of cell types populating the non-human primate embryos during gastrulation. We reconstructed three-dimensional digital models from serial sections of Cynomolgus monkey (Macaca fascicularis) gastrulating embryos at 1-day temporal resolution from E17 to E21. Spatial transcriptomics identifies gene expression profiles unique to the germ layers. Cross-species comparison reveals a developmental coordinate of germ layer segregation between mouse and primates, and species-specific transcription programs during gastrulation. These findings offer insights into evolutionarily conserved and divergent processes during mammalian gastrulation.
This Supplemental Materials containing Table S1-7, Supplementary file 1-10 and Supplementary video 1. They are also available at our website: http://sop.ccla.ac.cn.
DOI: 10.17632/xrthvhmdf9.1
title: Media Exposure - Adolescents

description: Data
DOI: 10.17632/96w9wxp42w.1
title: 2022 design of unit cell with Negative Poisson's ratio

description: Stl data of the unit cell with negative poisson's ratio. The detail of the design method is discussed in the paper:
DOI: 10.17632/gt7vskw4hv.1
title: Problematic Internet Use and its effects on Somatic Symptoms, Hyperventilation and Chronic Fatigue Syndrome among Youth 

description: 500 students were selected from six different colleges through stratified random sampling, out of which 448 data was selected for final analysis after data screening.  Internet usage scale measured problematic internet use, Somatic symptom disorder –B criteria scale measured three psychological criteria interpreted as cognitive, affective and behavioural aspects. Nijmegen questionnaire and Chalder fatigue scale assessed hyperventilation and chronic fatigue syndrome respectively.
DOI: 10.17632/n8pkb4tzyz.1
title: Supplementary Table 1 -A pharmacovigilance study of terbinafine indication and liver enzyme elevation

description: Supplemental Table I. Reporting Numbers according to Age Group and Sex for Both FAERS and CVARO Databases. Details on patient demographics, notably age and sex, of patients reporting LEE events with terbinafine usage.
DOI: 10.17632/ncsbbw5xjk.1
title: Morphologic characteristics of cutaneous immune-related adverse events in patients receiving immune checkpoint inhibitors combined with other anticancer therapies: A multicenter retrospective study (Supplemental File)

description: This file includes additional methodological details and data.
DOI: 10.17632/7jzgfwhznn.2
title: Design and implementation of a versatile magnetic field mapper

description: Mapping out magnetic field profiles from arbitrarily shaped magnets is an essential step in research, manufacturing, and maintenance. It helps you find out what’s under the surface of any object and identify areas of high-flux density in addition to determining field homogeneity which can be crucial for magnetic spectroscopy. Our magnetic field mapper is easy-to-use, has a user-friendly interface, and can be operated remotely. The mapper is a triple axis Hall effect-based magnetometer, which means that it can measure the strength of magnetic fields in 3D. It is made up of three Hall sensors which are mounted on a triple-slot sensor probe which is attached to translation stages allowing motion in three dimensions. The translation in X and Y motion (independent) is from −50 to +50 mm while in Z is from −150 to +150 mm with a nominal resolution of 0.1 mm. The height of the magnetometer is 1000 mm and it’s specially design for mapping the magnetic fields for permanent magnet assemblies used in low-field or mobile NMR applications. The mapper is low cost and easy to manufacture. All the required material are easy to find and in this database we provide all the designs required to replicate this instrument.
DOI: 10.17632/twkw889nmd.1
title: A dataset of an extended SEPIC DC-DC converter for micro-grid based photovoltaic (PV) applications

description: A single-ended primary inductor converter (SEPIC) direct current to direct current (DC-DC) converter was designed and incorporated with a photovoltaic (PV) panel in this article. A dataset of voltage gain at the expense of varied values of duty-cycle was generated. Besides, a data of voltage stress across the semiconductor components were obtained to determine the feasibility of the components used in designing the extended SEPIC converter. One of the aims of generating these data was to boost the low energy generated by the panel to a higher energy value with less complexity. For voltage gain data, a duty-cycle value was varied from 0.5 to 0.9 (50% to 90%) and the data obtained for the voltage gain was recorded. For voltage stress data, a voltage across individual active component of the converter was measured. These data could be reused by researchers interested in incorporating PV panel with a DC-DC boost converter for off-grid modelling.
DOI: 10.17632/cpb3skbrhn.1
title: Neuronal paxillin and drebrin mediate BDNF-induced force transduction and growth cone turning in a soft tissue-like environment

description: Soft tissue environments govern neuronal morphogenesis. However, the precise molecular mechanisms underlying chemotropism-directed axonal growth cone movement in extremely soft environments remain unclear. Here, we show that drebrin, a growth cone T-zone protein, modulates growth cone turning in response to BDNF coated on a soft substrate. Structurally, axonal growth cones of rodent hippocampal neurons grown on 0.1 kPa hydrogels possess an expanded T-zone in which drebrin is highly integrated with both F-actin and microtubules. Biochemically, we identify paxillin as interacting with drebrin in cells grown on 0.1 kPa hydrogels but not on glass coverslips. When grown on 0.1 kPa substrates, growth cones asymmetrically exposed to BDNF-bound stripes exhibit enhanced paxillin/drebrin interaction on the side facing the stripes, an activity that is PKA- and AAK1-dependent, but independent of Src kinase. Functionally, we show that BDNF-induced growth cone turning and force generation on soft substrates require drebrin phosphorylation and paxillin/drebrin association.
DOI: 10.17632/ysdxb6557d.2
title: Ensemble Classification using Balanced Data to Predict Customer Churn: A Case Study on the Telecom Industry

description:  This research examines the factors affecting customer churn in the telecom industry. In this regard, we use data mining classification methods, such as neural network, K-nearest neighbor, support vector machine, logistic regression, decision tree, and random forest. The results are analyzed using various criteria such as accuracy, precision, recall, F1-score, and ROC curve. After determining the successful classifiers, we combine them with the AdaBoost and XGBoost methods.
DOI: 10.17632/fprbxjtrzy.1
title: Exploitation of high tumour GSH levels for targetted siRNA delivery in rhabdomyosarcoma cells

description: Background: Metastatic alveolar rhabdomyosarcoma (aRMS) is an aggressive paediatric cancer with a poor prognosis. Downregulation of critical tumour genes using targetted siRNA has the potential to improve patient outcomes. However, the delivery of siRNA remains an obstacle, and association with nanoparticles could help to deliver, protect, target, and enhance penetration. The addition of near-infrared (NIR) dyes to the nanosystem can enable monitoring of uptake and accumulation during treatment.
Methods: In this study, two siRNA targeting options were selected and validated: (i) Human αB-crystallin (CRYAB) & Heat Shock Protein Family B (Small) Member 2 (HSPB2), and (ii) Keratin 17 (KRT17). A mesoporous silica based theranostic nanosystem was loaded with IR820 dye and linked to the siRNA via disulfide bonds. The system was characterized and evaluated for transfection efficiency and signalling. In addition, the metabolic effects and cell proliferation were monitored in 2D culture and also in 3D spheroid models. 
Results: The synthesized nanosystem was found to maintain a strong bond with the siRNA  molecules, and showed a high degree of protection; preventing degradation with RNase I during a 24 h incubation. The siRNA was effectively delivered and transfected into the aRMS cells by the nanosystem with a significant suppression of viability; 53.21 ± 23.40 % for CRYAB & HSPB2 siRNA, and 88.06 ± 17.28 % for KRT17 siRNA. The cause of cellular proliferation suppression was discovered with over 50% of cell apoptosis and necrosis within the RH30 spheroids were found after 72 h of nanosystem delivered siRNA transfection. Moreover, it has been demonstrated that the IR820 cellular uptake rate and penetration depth was significantly improved through the stable loading into the nanosystem. 
Conclusions: A successful theranostic nanosystem was generated that combined targeting siRNA treatment with IR820 NIR monitoring. This may help to pave the way for less invasive and more effective treatment of aRMS.
DOI: 10.17632/pdmgg3h58g.1
title: Supplemental data

description: Supplemental Tables 1-3 and Figures 1-3
DOI: 10.17632/rjm7hfsy2v.1
title: Dataset: Comparison of point-of-care testing with laboratory testing of the international normalized ratio in patients receiving long-term vitamin K antagonist treatment

description: The dataset contains paired INR measurements of point-of-care and laboratory testing from 1,846 patients with each three individual INR comparisons, in total 5,538 paired INR measurements of point-of-care and laboratory testing. Data is gathered from March 2015 to March 2016 at the Anticoagulation Clinic at Bispebjerg-Frederiksberg Hospital, Denmark. Besides INR measurements, the dataset contains vitamin K antagonist treatment indication, age, sex and months between 1st and 3rd INR measurement.
DOI: 10.17632/65kffmcgpp.1
title: Body composition and handgrip strength in Brazilian Jiu-Jitsu: a systematic review

description: Data for "Body composition and handgrip strength in Brazilian Jiu-Jitsu: a systematic review"
DOI: 10.17632/6rrwfvzbx5.2
title: An alternative ephemeris of comet 2P/Encke which explains the Taurid Meteoroid Complex

description: In a recent paper*, we examined the influence of alternative ephemerides for comet 2P/Encke on the formation of the Taurid Meteoroid Complex (TMC). Among the 114 stream formation scenarios explored, we found a specific orbital history of the comet which explains the main features of the major Taurid meteor showers (NTA & STA, BTA & ZPE). The agreement between our simulations and the general TMC characteristics indicates that this particular orbital evolution is likely the closest available "history" of the recent dynamical evolution of 2P/Encke. This specific ephemeris of 2P/Encke, labelled "A4", is provided here to help understanding the dynamical evolution of this particular comet. 

* "A Proposed Alternative Dynamical History for 2P/Encke which Explains the Taurid Meteoroid Complex", A. Egal, P. Wiegert & P. G. Brown, MNRAS
DOI: 10.17632/ccdppxc6pb.1
title: Dataset on Working conditions and stressors and perceived mental health among Iranian healthcare workers

description: The survey’s data aimed at collecting information on topics reflecting occupational risk factors and mental health among hospital nurses during the Covid-19 pandemic. We collected data on variables including gender, marital status, employment status, occupational health training, evaluation of work environment stressors, fear of Covid-19, and occupational burnout constructs, specifically reflecting emotional exhaustion, depersonalization, and personal accomplishment.Data from this study may provide invaluable resource for researcher, and workplace well-being units to better understand nurses’ working conditions and health outcomes in hospital settings.
DOI: 10.17632/fj3422ckc9.1
title: Dermatologic Adverse Events Associated with Immune Checkpoint Inhibitors in Melanoma: A Network Meta-Analysis of Randomized Trials

description: eFigure 1 Flowchart of trial selection
eTable 1. Trial characteristics
eTable 2. P-scores and best safety rankings for rash and pruritus in network meta-analyses. The P-score measures the extent of certainty that a treatment is better than another treatment, averaged over all competing treatments; a greater P-score indicates a higher likelihood of being the treatment with best safety for rash/pruritus.
DOI: 10.17632/r7gj93tvz9.1
title: Experimental investigation in an insulated box (Average temperature) 

description: The detailed description of data can be found in Experimental condition.docx
The data was categorized by
-	Measurement position
-	Phase Change Material (PCM) position: on a side wall and at the top
-       Loading condition: empty, extruded polystyrene (XPS) and test product (TP)
For example
C01 Temperature X-250mm Side Empty.xlsx: at X = 250 mm in a box with PCM on a side wall (empty)
C01 Temperature Y-145mm Side Empty.xlsx: at Y = 145 mm in a box with PCM on a side wall (empty)
C02 Temperature X-250mm Top Empty.xlsx: at X = 250 mm in a box with PCM at the top (empty)
C03 Temperature X-250 mm Side XPS: at X = 250 mm in a box with PCM on a side wall (XPS)
C05 Temperature X-250 mm Side TP: at X = 250 mm in a box with PCM on a side wall (TP)
DOI: 10.17632/yjbpwtx3c4.1
title: Experimental investigation in an insulated box (Air velocity)

description: The detailed description of data can be found in Experimental condition.docx
The data was categorized by
-	Measurement position
-	Phase Change Material (PCM) position: on a side wall and at the top
-       Loading condition: empty, extruded polystyrene (XPS) and test product (TP)
For example
C01 Air velocity X-250mm Side Empty.xlsx: at X = 250 mm in a box with PCM on a side wall (empty)
C01 Air velocity Y-145mm Side Empty.xlsx: at Y = 145 mm in a box with PCM on a side wall (empty)
C02 Ait velocity X-250mm Top Empty.xlsx: at X = 250 mm in a box with PCM at the top (empty)
C03 Air velocity X-250 mm Side XPS: at X = 250 mm in a box with PCM on a side wall (XPS)
C05 Air velocity X-250 mm Side TP: at X = 250 mm in a box with PCM on a side wall (TP)
DOI: 10.17632/rj5fybnzh6.1
title: The effects of cricket meal (Gryllus sigillatus) on the meat quality, growth, and internal morphology of broiler chickens

description: This research was originally conducted to meet the requirements of an MSc Thesis by Holly Fisher in 2021 at Dalhousie University in the Faculty of Agriculture in the Department of Animal Science, Bible Hill, NS, Canada, titled, “Evaluation of cricket meal (Gryllus sigillatus) and black soldier fly meal (Hermetia illucens) when incorporated in broiler chicken (Gallus gallus) diets," and specifically accompanies the chapter, "The impact of cricket meal (Grillus sigillatus) on the meat quality, growth, and internal morphology of broiler chickens," within the same thesis. 

Abstract 
Access to protein sources for use in animal feeds is vital to ensuring food security and efficient food production. This study investigates the dietary inclusion of cricket (Gryllus sigillatus) meal (CM) at dietary inclusion rates of 0% (non-medicated control; NM), 0% (medicated control), 5, 10, 15, and 20% CM (all non-medicated), and its impact on the growth parameters, internal morphology, and meat quality of Ross 308 broiler chickens (n=624 total; 26 birds/pen). Bird weight and feed intake were recorded weekly, and growth parameters were calculated. On days 13, 20, and 35, organ indices were calculated for three birds/pen. On day 35, meat quality was analyzed. The final average live weight of broilers fed 5% CM (1933.4 g) was lower than broilers fed the 10% CM (2063.5 g; P<0.05) and the 0% NM diets (2095.6 g; P<0.05). The total weight gain of chickens fed 5% CM (54.1 g/day) was lower than that of chickens fed all other treatments (P<0.05). A significant difference was observed in the small intestine of the chickens fed 5% CM (7.9%) on day 20 compared to all other treatments. Feed treatments did not influence meat texture or colour. Cooking loss in birds fed the 10% CM diet (35.5%) was significantly higher than that of birds fed the 0% NM control (31.9%). Results indicate that CM included in up to 20% of the diet had no detrimental impact on the growth, internal morphology, and meat quality of broiler chickens. Further research is required to determine whether a dietary inclusion of >20% CM will produce the same results.
DOI: 10.6084/m9.figshare.20147192
title: PISCO_SWAT_Cuenca_Ramis_CJTG

description: SWAT outputs simulated from the PISCO Product corresponding to the period 1981-2016.
DOI: 10.6084/m9.figshare.20147192.v7
title: PISCO_SWAT_Cuenca_Ramis_CJTG

description: SWAT outputs simulated from the PISCO Product corresponding to the period 1981-2016.
DOI: 10.6084/m9.figshare.20147192.v6
title: PISCO_SWAT_Cuenca_Ramis_CJTG

description: SWAT outputs simulated from the PISCO Product corresponding to the period 1981-2016.
DOI: 10.17632/46pxcbzty8.1
title: Forecasting climate-driven extinction risk and distributional change of the Karner blue butterfly to guide managed relocation

description: The Karner blue butterfly (Kbb) (Plebejus samuelis) is a federally listed endangered species whose decline is exacerbated by climate change. Evaluating how climate shapes population dynamics and the distribution of the Kbb may help develop adaptation plans. We applied mixed endo-exogenous models to examine the extinction risk and the likely distributional shift of some existent Kbb populations under several climatic change scenarios (elevated temperature and increased precipitation variance) by 2049. The predictions showed that local management of Kbb populations in Central Wisconsin and at Indiana Dunes National Park might not have been sufficient to mitigate adverse effects of climate change, and Kbbs were projected to reach higher abundance in the northern Midwest. These results suggest that some threatened populations might benefit from managed relocation and that it would be possible to reintroduce the Kbb back to Minnesota. To identify target sites for relocation, we overlapped model projections with the Minnesota soil classification map. We found a large expanse of sandy and loamy sandy soils geographically coincident with high climatic suitability for the Kbb.  If those areas were planted with the host wild lupine (Lupinus perennis) and other native nectar plants, they have the potential to be developed as climate refugia of this imperiled butterfly. However, habitat management in currently occupied sites can be a more effective conservation strategy for populations with lower extinction risks.

The uploaded data include 1. future climate envelops of the upper Midwest region till 2049 we extracted from the four RCPs of GFDL in terms of mean, max, and min temperature and total precipitation as well as three additional scenarios (+0.5/1%, +1.0/2%, +1.5/3%), which are the inputs of our endo-exogenous models for prediction; 2. all the pseudo-extinction risk outputs for each population and ecoregion, as well as four-way ANOVA test results of pairwise comparison between treatments (i.e., four climate scenarios, two habitat areas, four time windows, and two models); 3. all the projected maps of suitable habitats in the upper Midwest for the populations in each of the five ecoregions; 4. Some demo codes for extracting raw climate date and making predictions.
DOI: 10.17632/5ydr2s8v7f.1
title: Strategy searches: Dynamic resistance exercise and clinical biomarkers in adults with metabolic syndrome a protocol of systematic review and meta-analysis

description: Annex of information resources and searches strategies for dynamic resistance exercise and clinical biomarkers in adults with metabolic syndrome
DOI: 10.17632/kv3wjbndgw.1
title: “Decommunized” Concepts-Toponyms 

description: Ми ставили завдання виявити реакції мовців на концепти, що віддзеркалюють такий важливий суспільний процес в Україні, як ДЕКОМУНІЗАЦІЯ та її результат – перейменування міст. Ми обрали дві нові назви українських міст КРОПИВНИЦЬКИЙ та ГОРІШНІ ПЛАВНІ, оскільки саме в цих містах були зафіксовані протестні заходи місцевих жителів щодо зміни топонімів. 
Ми опитали 556 респондентів. Із них – 324 особи, що проживають у м. Кропивницькому (колишній Кіровоград) та 232 – у Горішніх Плавнях (колишній Комсомольськ). Нам було важливо охопити широку вікову аудиторію від 18 до 69 років, залучивши однакову кількість жінок та чоловіків (по 278), а також врахувавши, рівну кількість осіб серед тих, які хоча б рік навчалися в школі в добу СРСР (18-38 років), і тих, які вчилися тільки в незалежній Україні (39-69 років). Однак реакції окремо по кожній із цих категорій не розподілялися. Результати вираховувалися від загальної кількості реакцій.
Учасникам асоціативного експерименту було поставлено такі питання: 1) «назвіть одну свою реакцію на поняття ДЕКОМУНІЗАЦІЯ»; 2) «назвіть одну свою реакцію на назву міста КРОПИВНИЦЬКИЙ (для жителів Кропивницького) / ГОРІШНІ ПЛАВНІ (для жителів Горішніх Плавнів)». 
Отже, нами було отримано 1112 реакцій (556 – на стимул ДЕКОМУНІЗАЦІЯ, 324 – на КРОПИВНИЦЬКИЙ, 232 – на ГОРІШНІ ПЛАВНІ. Опитування мало індивідуальний характер. Питання було поставлене реципієнту один на один, а не в групі.  
Багато реакцій повторюються. Тому ми подавали реакцію, а біля неї ставили цифру, яка вказує на те, скільки людей відреагували саме такою рефлексемою, наприклад: "ощищення – 21". Через це в таблицях було уведено таке позначення, як наприклад: 88 рефлексем (358 відповідей), скорочено - 88 (358), де перша цифра означає кількість різних реакцій на той самий стимул, а цифра в дужках позначає кількість людей, які ці реакції продемонстрували. Перша цифра завжди буде меншою, оскільки деякі реакції у респондентів повторюються і рахуються як одна, а друга цифра (більша) показує кількість осіб.
DOI: 10.17632/hc3bct2byc.1
title: Raw data on fiber-reinforced cementitious composite subjected to high temperature

description: Raw data for manuscript entitled "A multiscale investigation on the performance improvement of fiber-reinforced cementitious composites after exposure to high temperatures" in Cement and Concrete Composites, and co-submitted article entitled “Experimental dataset on the residual performance of fiber-reinforced cementitious composite subjected to high temperature” in Data in Brief.