cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7980719
title: Additional file 7: of RNA-Seq and iTRAQ reveal multiple pathways involved in storage root formation and development in sweet potato (Ipomoea batatas L.)

description: Table S4. Correlation between transcriptome and proteome. (XLSX 1344 kb)
DOI: 10.6084/m9.figshare.7980725.v1
title: Additional file 9: of RNA-Seq and iTRAQ reveal multiple pathways involved in storage root formation and development in sweet potato (Ipomoea batatas L.)

description: Table S5. The detailed information of each GO functional category of proteomic analysis. (XLS 1085 kb)
DOI: 10.6084/m9.figshare.7980794.v1
title: MOESM1 of Small nucleolar RNA Sf-15 regulates proliferation and apoptosis of Spodoptera frugiperda Sf9 cells

description: Additional file 1: Table S1. Differentially expressed gene list upon Sf-15 overexpression and repression. ASO and Sf-15 means cells were transfected with antisense oligonucleotides of Sf-15 and overexpression vector pBac[A3-EGFP-A3-Sf-15], respectively.
DOI: 10.6084/m9.figshare.20039498
title: Evaluation of antiarthritic activity of ginkgolic acid against Freund’s adjuvant induced arthritic rat model

description: This study aimed to analyze the antiarthritic activity of ginkgolic acid against the Complete Freund’s Adjuvant (CFA)-induced arthritis in rats. Arthritis was induced through an intradermal injection of CFA (0.1 mL) at the right hind footpad of adult Wistar Albino rats. Ginkgolic acid was administered orally at doses of 25 mg/kg and 50 mg/kg, respectively, once daily via gavage for 25 days upon inducing arthritis. Indomethacin was administered orally at a dose of 3 mg/kg twice in a week which served as positive control group. The animals were sacrificed and subjected to biochemical and histopathological analysis upon completion of treatment. Ginkgolic acid was able to reverse the arthritic effect (p &lt; 0.01) induced by CFA in a dose dependent manner. Swelling of paw, thymus and spleen index, serum biomarker levels, and pro-inflammatory cytokines were significantly reduced (p &lt; 0.01) by the acid whereas the antioxidant enzyme activities were remarkably restored. The histopathological findings were in agreement with the biochemical results. The results indicate that the antioxidant and anti-inflammatory properties of ginkgolic acid can be credited to the antiarthritic effects, and it can be promoted as a potential agent for therapeutic use against osteoarthritis.
DOI: 10.6084/m9.figshare.14267106
title: Additional file 2 of Epigenome-wide association study of whole blood gene expression in Framingham Heart Study participants provides molecular insight into the potential role of CHRNA5 in cigarette smoking-related lung diseases

description: Additional file 2. Supplemental Tables.
DOI: 10.6084/m9.figshare.18462000
title: Additional file 1 of A prognostic model based on immune-related long noncoding RNAs for patients with epithelial ovarian cancer

description: Additional file 1. Supplementary Table S1: A list of 2483 immune-related genes from ImmPort.
DOI: 10.6084/m9.figshare.18462003
title: Additional file 2 of A prognostic model based on immune-related long noncoding RNAs for patients with epithelial ovarian cancer

description: Additional file 2. Supplementary Table S2: A list of 421 differentially expressed immune-related lncRNAs.
DOI: 10.6084/m9.figshare.18461837
title: Additional file 3 of Differential proteomic analysis demonstrates follicle fluid participate immune reaction and protein translation in yak

description: Additional file 3. Upregulated DEPs in immature FF.
DOI: 10.6084/m9.figshare.18462033
title: Additional file 1 of Investigating the genomic alteration improved the clinical outcome of aged patients with lung carcinoma

description: Additional file 1: Table S1-S4.
DOI: 10.6084/m9.figshare.18462033.v1
title: Additional file 1 of Investigating the genomic alteration improved the clinical outcome of aged patients with lung carcinoma

description: Additional file 1: Table S1-S4.
DOI: 10.6084/m9.figshare.7452026.v1
title: Inhibitory effect of reduced graphene oxide-silver nanocomposite on progression of artificial enamel caries

description: Abstract The use of antimicrobial agents is an efficient method to prevent dental caries. Also, nanometric antibacterial agents with wide antibacterial spectrum and strong antibacterial effects can be applied for prevention of dental caries. Objectives: The aim of this study was to evaluate the inhibitory effect of reduced graphene oxide-silver nanoparticles (rGO/Ag) composite on the progression of artificial enamel caries in a Streptococcus mutans biofilm model. Material and Methods: Enamel specimens from bovine incisors were divided into eight treatment groups (n = 13), as follows: group 1 was inoculated with S. mutans grown in Brain Heart Infusion containing 1% sucrose (1% BHIS), as negative control; groups 2-4 were inoculated with S. mutans grown in the presence of different rGO/Ag concentrations (0.08, 0.12, 0.16 mg/mL) + 1% BHIS; group 5-7 were inoculated with S. mutans grown in the presence of different agents (0.16 mg/mL reduced graphene oxide, 0.16 mg/mL silver nanoparticles, 10 ppm NaF) + 1% BHIS; group 8 was mixed with 1% BHIS, without inoculation. Artificial enamel carious lesions were produced by S. mutans biofilm model for 7 days. Confocal laser scanning microscopy and atomic force microscopy were used to analyze roughness and morphology of the enamel surface. Polarized light microscopy and confocal laser scanning microscopy were employed to measure the lesion depth and the relative optical density (ROD) of the demineralized layer. Results: Compared with the control groups, the rGO/Ag groups showed: (a) reduced enamel surface roughness; (b) much smoother and less eroded surfaces; (c) shallower lesion depth and less mineral loss. Conclusion: As a novel composite material, rGO/Ag can be a promising antibacterial agent for caries prevention.
DOI: 10.6084/m9.figshare.22661179
title: Tectono‑magmatic control on the intensity of decratonic gold mineralization in the southeastern margin of the North China Craton: A perspective from geochemical comparison

description: The North China Craton (NCC), notably the southeastern margin of the NCC, hosts the most typical example of decratonic gold deposits. However, the factors controlling the intensity of decratonic gold mineralization and the relation between the geodynamic model of decratonization and gold mineralization still deserve to be well elucidated. The Bengbu and the Jiaobei uplifts are located at the southeastern margin of the NCC and the two uplifts have similar tectonic positions and metamorphic basements, yet the intensity of gold mineralization is quite distinct. Mesozoic mineralization and magmatism in both uplifts are controlled by the same deep geodynamic process. Accordingly, in this review, we make an effort to find solutions to these problems by integrating the whole-rock geochemical and Sr-Nd-Pb isotopic data as well as zircon U-Pb-Hf-O isotopic data from late Mesozoic magmatic rocks from the Bengbu uplift and the Jiaobei uplift. The late Mesozoic magmatism of the two uplifts can be divided into three stages, i.e. Late Jurassic (stage I), middle Early Cretaceous (stage II), and late Early Cretaceous (stage III). Comparative studies of the gold-related rocks in these two areas indicate that the intensity of the decratonic gold mineralization is controlled by magmatic source composition (i.e. the affinity of the upper crust of the South China Block), intrinsic magmatic variables of gold-related rocks (i.e. redox state and volatiles content), as well as lithospheric architecture (i.e. lithospheric thickness). Additionally, the integrated data of magmatic rocks in the three stages suggest that plate subduction acts as the recycling engine factory responsible for the decratonic mineral systems. In the early stage (Triassic), continental subduction of the South China Block induced pre-enrichment of ore-forming nutriments in magma sources, whereas in the late stage (Early Cretaceous), oceanic subduction of the paleo-Pacific plate led to the craton destruction, thereby triggering related magmatism and gold mineralization in the eastern NCC.
DOI: 10.6084/m9.figshare.22661179.v1
title: Tectono‑magmatic control on the intensity of decratonic gold mineralization in the southeastern margin of the North China Craton: A perspective from geochemical comparison

description: The North China Craton (NCC), notably the southeastern margin of the NCC, hosts the most typical example of decratonic gold deposits. However, the factors controlling the intensity of decratonic gold mineralization and the relation between the geodynamic model of decratonization and gold mineralization still deserve to be well elucidated. The Bengbu and the Jiaobei uplifts are located at the southeastern margin of the NCC and the two uplifts have similar tectonic positions and metamorphic basements, yet the intensity of gold mineralization is quite distinct. Mesozoic mineralization and magmatism in both uplifts are controlled by the same deep geodynamic process. Accordingly, in this review, we make an effort to find solutions to these problems by integrating the whole-rock geochemical and Sr-Nd-Pb isotopic data as well as zircon U-Pb-Hf-O isotopic data from late Mesozoic magmatic rocks from the Bengbu uplift and the Jiaobei uplift. The late Mesozoic magmatism of the two uplifts can be divided into three stages, i.e. Late Jurassic (stage I), middle Early Cretaceous (stage II), and late Early Cretaceous (stage III). Comparative studies of the gold-related rocks in these two areas indicate that the intensity of the decratonic gold mineralization is controlled by magmatic source composition (i.e. the affinity of the upper crust of the South China Block), intrinsic magmatic variables of gold-related rocks (i.e. redox state and volatiles content), as well as lithospheric architecture (i.e. lithospheric thickness). Additionally, the integrated data of magmatic rocks in the three stages suggest that plate subduction acts as the recycling engine factory responsible for the decratonic mineral systems. In the early stage (Triassic), continental subduction of the South China Block induced pre-enrichment of ore-forming nutriments in magma sources, whereas in the late stage (Early Cretaceous), oceanic subduction of the paleo-Pacific plate led to the craton destruction, thereby triggering related magmatism and gold mineralization in the eastern NCC.
DOI: 10.6084/m9.figshare.18462003.v1
title: Additional file 2 of A prognostic model based on immune-related long noncoding RNAs for patients with epithelial ovarian cancer

description: Additional file 2. Supplementary Table S2: A list of 421 differentially expressed immune-related lncRNAs.
DOI: 10.6084/m9.figshare.7976390
title: Nd:YAG Laser for Ahmed Tube Shunt Blockage in Patients Implanted with Boston Type I Keratoprosthesis

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DOI: 10.6084/m9.figshare.14791347.v1
title: In vitro activities of the tetrazole VT-1161 compared with itraconazole and fluconazole against <i>Cryptococcus</i> and non-<i>albicans Candida</i> species

description: Recently, <i>Cryptococcus</i> and non-<i>albicans Candida</i> (NAC) have emerged as health-threatening pathogens for clinical fungal infections. Due to their increased resistance to existing antifungal drugs, novel antifungals are urgently needed. In this study, we evaluated the antifungal effect of VT-1161 and its comparators itraconazole and fluconazole against common fluconazole-sensitive or -resistant <i>Cryptococcus</i> and NAC strains. The tested strains were obtained from Chinese patients by the Invasive Fungal Infection Group within the past 2 years. The minimum inhibitory concentrations (MICs) of VT-1161 and other triazoles were measured according to the Clinical and Laboratory Standards Institute (CLSI) M27-Ed4 guidelines. We found that VT-1161 exhibited strong in vitro activity against <i>Cryptococcus</i> spp.. VT-1161 (geometric mean MIC = 0.024 μg/mL) was 21.7-fold and 104.5-fold more potent than itraconazole and fluconazole, respectively. Against the seven <i>Cryptococcus neoformans</i> isolates with higher fluconazole MICs (≥8 μg/mL based on the MIC<sub>90</sub> value of this azole), VT-1161 maintained potent activities, with MICs ranging between 0.031 and 0.5 μg/mL. For NAC spp., VT-1161 (geometric mean MIC = 0.099 μg/mL) was 6.0-fold and 11.4-fold more effective than itraconazole and fluconazole, respectively. There is a positive correlation of the MICs between VT-1161 and itraconazole/fluconazole. The MIC values of VT-1161 against <i>Candida glabrata</i> and <i>Candida tropicalis</i> were significantly lower than those of fluconazole, whereas for <i>Candida parapsilosis</i> the differences in the MIC values between VT-1161 and fluconazole were not statistically significant. The results showed that tetrazole VT-1161 might be a promising candidate for treating <i>Cryptococcus</i> and NAC infections.
DOI: 10.6084/m9.figshare.13219253.v1
title: Additional file 13 of Circular RNA hsa_circ_0004872 inhibits gastric cancer progression via the miR-224/Smad4/ADAR1 successive regulatory circuit

description: Additional file 13: Table S5. CircRNA-seq analysis of the differentially expressed circRNAs in GC tissue and corresponding nontumor tissue.
DOI: 10.6084/m9.figshare.7976390.v2
title: Nd:YAG Laser for Ahmed Tube Shunt Blockage in Patients Implanted with Boston Type I Keratoprosthesis

description: Full copyright for enhanced digital
features is owned by the authors.

 

<strong>Article full
text</strong>

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The full text of this article can be found <b>here</b>. <br>
<br>
<strong>Provide enhanced digital features for this article</strong><br>
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enhanced digital features for your article then please contact adisrapidplus@springer.com.<br>
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Moreover, all sponsorship and disclosure information is included to provide
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that however the content is reached the reader has a full understanding of its
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DOI: 10.6084/m9.figshare.7976390.v1
title: Nd:YAG Laser for Ahmed Tube Shunt Blockage in Patients Implanted with Boston Type I Keratoprosthesis: A Case Series

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<strong>Article full
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will be made available on this page in the next few days. <br>
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visibility and readership. All features will be thoroughly peer reviewed to
ensure the content is of the highest scientific standard and all features are
marked as ‘peer reviewed’ to ensure readers are aware that the content has been
reviewed to the same level as the articles they are being presented alongside.
Moreover, all sponsorship and disclosure information is included to provide complete
transparency and adherence to good publication practices. This ensures that
however the content is reached the reader has a full understanding of its
origin. No fees are charged for hosting additional open access content.<br>
<br>
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DOI: 10.6084/m9.figshare.18461831
title: Additional file 1 of Differential proteomic analysis demonstrates follicle fluid participate immune reaction and protein translation in yak

description: Additional file 1. All identified proteins.
DOI: 10.6084/m9.figshare.18461843
title: Additional file 5 of Differential proteomic analysis demonstrates follicle fluid participate immune reaction and protein translation in yak

description: Additional file 5. GO of upregulated DEPs in immature FF.
DOI: 10.6084/m9.figshare.22132328
title: Hybrid Transthoracic Periventricular Device Closure of Ventricular Septal Defects: Single-Center Experience

description: Abstract Objective: To evaluate the efficacy of hybrid transthoracic periventricular device closure of ventricular septal defects (VSDs) in a single center. Methods: All patients who underwent hybrid transthoracic periventricular device closure of VSDs between January 2018 and December 2019 were retrospectively analyzed. The preoperative, operative and postoperative findings and clinical follow-ups were reviewed. Results: A total of 59 patients underwent the procedure. Transesophageal echocardiographic guidance was used in all procedures. The procedure was successful in 57 procedures (97%). The procedures of two patients were changed to open-heart surgery during the same intervention due to severe aortic insufficiency (the device was not deployed) and significant residual shunt after device deployment. One major complication (1.7%) was observed after the procedure. The patient’s device was dislodged within 12 hours after the procedure, and this patient underwent device extraction and VSD patch closure due to significant residual shunt. Eight (14%) minor complications were observed after the procedure, and three of them persisted during follow-up. Three of these eight complications were incomplete right bundle branch block, one of which resolved during follow-up; two were mild residual shunts, one of which resolved during follow-up; two were mild new-onset tricuspid valve insufficiencies; and one was mild new-onset mitral valve insufficiency; all valvular insufficiencies were resolved during follow-up. Conclusions: Hybrid transthoracic periventricular device closure of VSD seems to be a good alternative approach due to its procedural success and low risk rates. The best advantage of the procedure is the possibility of switching to open-heart surgery, if necessary.
DOI: 10.6084/m9.figshare.22132422.v1
title: Myhre Syndrome Misdiagnosed as Marfan Syndrome: an Educational Presentation

description: Abstract A 32-month-old girl with patent ductus arteriosus, false tendon of left ventricle, mild pulmonary hypertension, and chronic cardiac insufficiency (cardiac function level I-II) was misdiagnosed with Marfan Syndrome and there was no improvement in her physical growth after operation for this disease. The preterm baby was finally diagnosed with Myhre Syndrome by clinical phenotypes and mutation of SMAD4 gene.
DOI: 10.6084/m9.figshare.19510895
title: Mitochondrial genome structure, phylogenetic analyses and substitution rate estimation of the Oedogoniales

description: The order Oedogoniales comprises three genera, <i>Oedogonium, Oedocladium</i> and <i>Bulbochaete</i>, which were classified based on traditional morphological criteria, and includes more than 600 described species. This group is economically important in astaxanthin production and the energy sector. However, only one mitochondrial genome (mitogenome) has been reported so far. This study determined the mitochondrial genomes of seven Oedogoniales species, including six <i>Oedogonium</i> species and <i>Oedocladium prescottii</i>. Comparative analyses between the newly determined mitogenomes and the previously reported <i>Bulbochaete rectangularis</i> var. <i>hiloensis</i> mitogenome showed that all eight mitogenomes comprised 12 protein-coding genes (PCGs) and two rRNAs; however, the mitogenomes differed in their genome sizes, GC content, tRNAs, non-coding regions and introns. Synteny analysis of the eight mitogenomes revealed a high degree of syntenic conservation in general, with some rearrangements and inversions. The average nucleotide identity (ANI) analysis of the eight mitogenomes indicated <i>Oedogonium dentireticulatum</i> showed high similarity with <i>Oedogonium</i> sp3 (ANI of 96.32%). Most of the PCGs of the eight mitogenomes presented the conventional start codon ATG and stop codon TAR (TAA/TAG/TGA), and the synonymous codon preferences were conserved. Phylogenetic results indicated that <i>Oedogonium</i> was polyphyletic, and species of <i>Oedocladium</i> clustered with <i>Oedogonium</i>, while the position of <i>B. rectangularis</i> var. <i>hiloensis</i> was uncertain for the incongruent phylogenetic results. Statistical analyses of substitution rates demonstrated no significant differences among the three genera, and the dN/dS ratios based on branch model showed that <i>cob, cox</i>1 and <i>nad</i>4 of <i>Oedocladium prescottii</i> and <i>B. rectangularis</i> var. <i>hiloensis</i> were putative fast-evolving genes. These findings suggested that the traditional taxonomy of Oedogoniales did not define natural groups, and that species of <i>Oedocladium</i> and <i>Bulbochaete</i> may have undergone rapid evolution.