cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.19905163.v1
title: Use of human bone marrow mesenchymal stem cells immortalized by the expression of telomerase in wound healing in diabetic rats

description: Diabetes mellitus is associated with neural and micro- and macrovascular complications. Therapeutic options for these complications are limited and the delivery of mesenchymal stem cells into lesions have been reported to improve the healing process. In this work, the effects of the administration of a lineage of human bone marrow mesenchymal stem cells immortalized by the expression of telomerase (hBMSC-TERT) as a potential therapeutic tool for wound healing in diabetic rats were investigated. This is the first description of the use of these cells in diabetic wounds. Dorsal cutaneous lesions were made in streptozotocin-induced diabetic rats and hBMSC-TERT were subcutaneously administered around the lesions. The healing process was evaluated macroscopically, histologically, and by birefringence analysis. Diabetic wounded rats infused with hBMSC-TERT (DM-TERT group) and the non-diabetic wounded rats not infused with hBMSC-TERT (CW group) had very similar patterns of fibroblastic response and collagen proliferation indicating improvement of wound healing. The result obtained by birefringence analysis was in accordance with that obtained by the histological analysis. The results indicated that local administration of hBMSC-TERT in diabetic wounds improved the wound healing process and may become a therapeutic option for wounds in individuals with diabetes.
DOI: 10.6084/m9.figshare.19905163
title: Use of human bone marrow mesenchymal stem cells immortalized by the expression of telomerase in wound healing in diabetic rats

description: Diabetes mellitus is associated with neural and micro- and macrovascular complications. Therapeutic options for these complications are limited and the delivery of mesenchymal stem cells into lesions have been reported to improve the healing process. In this work, the effects of the administration of a lineage of human bone marrow mesenchymal stem cells immortalized by the expression of telomerase (hBMSC-TERT) as a potential therapeutic tool for wound healing in diabetic rats were investigated. This is the first description of the use of these cells in diabetic wounds. Dorsal cutaneous lesions were made in streptozotocin-induced diabetic rats and hBMSC-TERT were subcutaneously administered around the lesions. The healing process was evaluated macroscopically, histologically, and by birefringence analysis. Diabetic wounded rats infused with hBMSC-TERT (DM-TERT group) and the non-diabetic wounded rats not infused with hBMSC-TERT (CW group) had very similar patterns of fibroblastic response and collagen proliferation indicating improvement of wound healing. The result obtained by birefringence analysis was in accordance with that obtained by the histological analysis. The results indicated that local administration of hBMSC-TERT in diabetic wounds improved the wound healing process and may become a therapeutic option for wounds in individuals with diabetes.
DOI: 10.6084/m9.figshare.19905164
title: Evaluation of preoperative data and post-operative results of phacotrabeculectomy in minimum five-year follow-up

description: ABSTRACT Objective: To evaluate the results of phacotrabeculectomy in a follow-up of five years or more. Methods: Retrospective, interventional and analytical study that was carried out in the surgical center of clínica de olhos do juazeiro with patients operated on from 2006 to 2013. 34 eyes of 29 patients with senile cataract and primary open-angle glaucoma, who underwent phacotrabeculectomy were involved in the investigation. A risk score for glaucomatous dam-age ranging from 0 to 5 when evaluating intraocular pressure, excavation of the optic disc, number of hypotensive drugs used to treat glaucoma and the patient's age in years. The sample was of convenience and paired. The paired Wilcoxon test was used to verify differences be-tween means. P &lt;0.05 was accepted for the rejection of the null hypothesis. The study was approved by the ethics committee of the Brazil platform and follows the principles of resolu-tion 466 of the National Health Council. Results: The mean visual acuity was significantly higher after a five-year follow-up (preoperative average 0.42 +/- 0.23 versus postoperative average 0.62 +/- 0.29 - p = 0.0031). The average risk score for glaucomatous damage after five years of follow-up was significantly lower when compared to the preoperative (preoperative mean: 9.47 +/- 1.61 versus postoperative mean 6.55 +/- 2, 21) p &lt;0.0001, considered extremely significant. Conclusion: Phacotrabeculectomy was significantly effective in improving visual acuity and reducing the risk of glaucomatous damage after a five-year postoperative follow-up.
DOI: 10.6084/m9.figshare.19905164.v1
title: Evaluation of preoperative data and post-operative results of phacotrabeculectomy in minimum five-year follow-up

description: ABSTRACT Objective: To evaluate the results of phacotrabeculectomy in a follow-up of five years or more. Methods: Retrospective, interventional and analytical study that was carried out in the surgical center of clínica de olhos do juazeiro with patients operated on from 2006 to 2013. 34 eyes of 29 patients with senile cataract and primary open-angle glaucoma, who underwent phacotrabeculectomy were involved in the investigation. A risk score for glaucomatous dam-age ranging from 0 to 5 when evaluating intraocular pressure, excavation of the optic disc, number of hypotensive drugs used to treat glaucoma and the patient's age in years. The sample was of convenience and paired. The paired Wilcoxon test was used to verify differences be-tween means. P &lt;0.05 was accepted for the rejection of the null hypothesis. The study was approved by the ethics committee of the Brazil platform and follows the principles of resolu-tion 466 of the National Health Council. Results: The mean visual acuity was significantly higher after a five-year follow-up (preoperative average 0.42 +/- 0.23 versus postoperative average 0.62 +/- 0.29 - p = 0.0031). The average risk score for glaucomatous damage after five years of follow-up was significantly lower when compared to the preoperative (preoperative mean: 9.47 +/- 1.61 versus postoperative mean 6.55 +/- 2, 21) p &lt;0.0001, considered extremely significant. Conclusion: Phacotrabeculectomy was significantly effective in improving visual acuity and reducing the risk of glaucomatous damage after a five-year postoperative follow-up.
DOI: 10.17632/dfgb37479r.1
title: Pathways for peat

description: Peatlands are the largest terrestrial carbon store in the world and store twice as much carbon as all forests. In the Netherlands, peatlands have been drained on a wide scale. This drainage has caused the accelerated decomposition of peat, resulting in subsidence and greenhouse gas emissions. In the light of these substantial greenhouse gas emissions, a shift is taking place in the management of peatlands.

The Dutch government has underlined this shift by its ambitions to limit greenhouse gas emissions from peatlands by 1,0 Mt CO2-eq in 2030, as described in the Climate Accord. The Dutch government has also committed itself to a reduction of greenhouse gas emissions of 95% in 2050, which will translate to a reduction of 3,9 Mt CO2-eq in 2050 compared to 1990. Provinces are currently developing strategies to achieve the goal in 2030 and a nationwide research program has been set up to monitor and model emissions better. 

Based on these ongoing strategies and programs, this study wants to illustrate possible combinations of intermediate steps that lead to reaching the reduction goals of 1,0 Mt CO2-eq reduction in 2030 and a reduction of 95%, 3,9 Mt, in 2050 for the Dutch peatlands by designing scenarios and pathways. This study will thereby answer the question: “What are possible pathways to reduce the GHG emissions of the Dutch peatlands with 1,0 Mt CO2-eq by 2030 and with 3,9 Mt by 2050 compared to 1990? “
DOI: 10.17632/ysky8r2wkd.1
title: Repository of 2D shapes with known roundness and sphericity

description: This repository contains 2D black and white jpg shapes with known Wadell roundness R and sphericity S. Its purpose is to serve as training and test images for roundness and sphericity measurement artificial vision algorithms, in particular with application to fracking sands.
The dataset contains 1300 figures that cover the full range of possible combinations of roundness R and sphericity S with 0.1<R<0.9 and 0.15<S<1, with steps of 0.05 in both R and S.
There are approximately 4.3 figures for each possible combination of R and S in the indicated ranges and steps.

The basic data set is in the artificial500 folder, where the files are on average 500px wide. The same figures are available in smaller average sizes of 100px and 200px in the artificial100 and artificial200 folders, in order to test the insensitivity of the measurement algorithms to image accuracy.

The artiShapes.xlsx excel sheet contains the true Wadell roundness and sphericity corresponding to each jpg filename.
DOI: 10.6084/m9.figshare.19905169
title: Palliative care in emergency services: an integrative review

description: Abstract This article seeks to understand the approach of emergency teams to patients with an advanced chronic condition from a palliative care perspective. This integrative review searched for articles in five databases using the descriptors “emergency medical services,” “patient assistance team,” “attitudes of health personnel” and “palliative care”. At first, 12,290 publications were identified, which were then reduced to 26 articles for the final sample. Among the main measures found in the literature to use palliative care in emergency services, the following stand out: individualized and flexible care plan; network management; access to the palliative care team; empathic communication; identification eligible patients; and control of symptoms. We thus conclude that emergency teams must recognize the importance of palliative care and redirect the care focused in “saving lives” towards a care that preserves human dignity.
DOI: 10.6084/m9.figshare.19905169.v1
title: Palliative care in emergency services: an integrative review

description: Abstract This article seeks to understand the approach of emergency teams to patients with an advanced chronic condition from a palliative care perspective. This integrative review searched for articles in five databases using the descriptors “emergency medical services,” “patient assistance team,” “attitudes of health personnel” and “palliative care”. At first, 12,290 publications were identified, which were then reduced to 26 articles for the final sample. Among the main measures found in the literature to use palliative care in emergency services, the following stand out: individualized and flexible care plan; network management; access to the palliative care team; empathic communication; identification eligible patients; and control of symptoms. We thus conclude that emergency teams must recognize the importance of palliative care and redirect the care focused in “saving lives” towards a care that preserves human dignity.
DOI: 10.6084/m9.figshare.19905170
title: Inclusion of genomic information in estimation of genetic parameters for body weights and visual scores in Nelore cattle

description: ABSTRACT The aim of this study was to evaluate genomic information inclusion in genetic parameter estimation of standardized body weight at birth and at 240, 365, and 450 days of age, and visual scores for body structure, precocity, and body muscularity, measured as yearlings in Nelore cattle. We compared genetic parameters, (co)variance components (estimated from Bayesian inference and Gibbs sampling), breeding value accuracies, genetic trends, and principal component analysis (PCA) obtained through traditional GBLUP and ssGBLUP methods. For all traits analyzed, part of the phenotypic variation was explained by the additive genetic effect, thus indicating the capacity of traits to respond to the selection process. Estimates of genetic correlation, in both methodologies, between body weights and visual scores were, in general, high and positive, showing that the selection for visual scores can lead to heavier animals. Genetic trends showed genetic progress, both when estimated breeding values and genomic estimated breeding values were used. The PCA, genetic trends, and accuracy estimates on breeding values showed that inclusion of single nucleotide polymorphism information contributed towards slightly better estimates of the genetic variability of evaluated traits. Genomic information did not bring greater gains in genetic estimates, due to redundancy of kinship information from the pedigree, which already had complete animal kinship data.
DOI: 10.6084/m9.figshare.19905170.v1
title: Inclusion of genomic information in estimation of genetic parameters for body weights and visual scores in Nelore cattle

description: ABSTRACT The aim of this study was to evaluate genomic information inclusion in genetic parameter estimation of standardized body weight at birth and at 240, 365, and 450 days of age, and visual scores for body structure, precocity, and body muscularity, measured as yearlings in Nelore cattle. We compared genetic parameters, (co)variance components (estimated from Bayesian inference and Gibbs sampling), breeding value accuracies, genetic trends, and principal component analysis (PCA) obtained through traditional GBLUP and ssGBLUP methods. For all traits analyzed, part of the phenotypic variation was explained by the additive genetic effect, thus indicating the capacity of traits to respond to the selection process. Estimates of genetic correlation, in both methodologies, between body weights and visual scores were, in general, high and positive, showing that the selection for visual scores can lead to heavier animals. Genetic trends showed genetic progress, both when estimated breeding values and genomic estimated breeding values were used. The PCA, genetic trends, and accuracy estimates on breeding values showed that inclusion of single nucleotide polymorphism information contributed towards slightly better estimates of the genetic variability of evaluated traits. Genomic information did not bring greater gains in genetic estimates, due to redundancy of kinship information from the pedigree, which already had complete animal kinship data.
DOI: 10.6084/m9.figshare.19905173
title: Vulnerability of patients with prostatic hyperplasia treated with dutasteride and finasteride

description: Summary Benign prostatic hyperplasia is a pathology whose incidence has been increasing in recent years throughout Brazil. The disease is correlated with hormonal factors, and pharmacological treatment can have adverse effects on patients. This study assesses the socioeconomic and socio-cultural factors that interfere with healing or reduce quality of life. We analyzed data from Federal Government platforms between January 2009 and September 2019, looking at factors such as ethnicity, education level and economic status of patients. In all regions of Brazil, these factors proved to be important, as they can directly affect the incidence of the disease and adherence and continuity of treatment.
DOI: 10.17632/w5fwx87dtk.2
title: Data for: Characterization of biodegradable/non-compostable films made from cellulose acetate/corn starch blends processed under reactive extrusion conditions

description: These files provide the transparent date of this article.
DOI: 10.6084/m9.figshare.19905175
title: Phasing out the pre-transplant cytotoxicity crossmatch: Are we missing something?

description: Abstract Introduction: The anti-human globulin-enhanced complement-dependent cytotoxicity crossmatch (AHG-CDCXM) assay has been used to assess the presence of donor-specific antibodies (DSA) in recipient’s serum before kidney transplantation. The flow cytometric crossmatch (FCXM) assay was first introduced as an additional test. The aim of this study was to clinically validate the single use of the FCXM assay. Methods: This study compared the outcomes of a cohort of kidney transplant patients that underwent FCXM only (FCXM group) versus a cohort of kidney transplant patients that underwent AHG-CDCXM (control group). Results: Ninety-seven patients in the FCXM group and 98 controls were included. All crossmatches in the control group were negative. One patient in the FCXM group had a positive B cell crossmatch. One year after transplantation, there were no significant differences in patient survival (p = 0.591) and graft survival (p = 0.692) between the groups. Also, no significant difference was found in the incidence of Banff ≥ 1A acute cellular rejection episodes (p = 0.289). However, acute antibody-mediated rejections occurred in 3 controls (p = 0.028). Conclusion: The results showed that discontinuing the AHG-CDCXM assay does not modify the clinical outcomes in a 1-year follow-up.
DOI: 10.6084/m9.figshare.19905175.v1
title: Phasing out the pre-transplant cytotoxicity crossmatch: Are we missing something?

description: Abstract Introduction: The anti-human globulin-enhanced complement-dependent cytotoxicity crossmatch (AHG-CDCXM) assay has been used to assess the presence of donor-specific antibodies (DSA) in recipient’s serum before kidney transplantation. The flow cytometric crossmatch (FCXM) assay was first introduced as an additional test. The aim of this study was to clinically validate the single use of the FCXM assay. Methods: This study compared the outcomes of a cohort of kidney transplant patients that underwent FCXM only (FCXM group) versus a cohort of kidney transplant patients that underwent AHG-CDCXM (control group). Results: Ninety-seven patients in the FCXM group and 98 controls were included. All crossmatches in the control group were negative. One patient in the FCXM group had a positive B cell crossmatch. One year after transplantation, there were no significant differences in patient survival (p = 0.591) and graft survival (p = 0.692) between the groups. Also, no significant difference was found in the incidence of Banff ≥ 1A acute cellular rejection episodes (p = 0.289). However, acute antibody-mediated rejections occurred in 3 controls (p = 0.028). Conclusion: The results showed that discontinuing the AHG-CDCXM assay does not modify the clinical outcomes in a 1-year follow-up.
DOI: 10.17632/zp73gjphws.2
title: Data for: In-depth study from gluten/PCL-based food packaging films obtained under reactive extrusion conditions using chrome octanoate as a potential food grade catalyst

description: These files provide the transparent date of this article.
DOI: 10.17632/38wd6dyvnd.2
title: Data for: In vitro and in vivo digestibility from bionanocomposite edible films based on native pumpkin flour/plum flour

description: These files provide the transparent date of this article.
DOI: 10.17632/786d8rmc8x.2
title: Data for: Hydrogen-bonding interactions and compostability of bionanocomposite films prepared from corn starch and nano-fillers with and without added Jamaica flower extract

description: These files provide the transparent date of this article.
DOI: 10.17632/7n5sr97dng.1
title: Data for: Reactive extrusion-processed shape-memory food packaging films made from native and carboxymethylated plantain flour/polystyrene blends

description: These files provide the transparent date of this article.
DOI: 10.6084/m9.figshare.19905179.v1
title: Enteral nutrition in older adults with dementia in palliative care

description: Abstract The number of older adults and, consequently, the incidence of chronic non-communicable diseases, including dementia, have increased exponentially. Dementia leads to progressive loss of functionality, including food-related complications. This article presents results of an integrative review on the current scientific evidence of enteral nutritional therapy in patients with dementia in palliative care. Articles published between 2009 and 2019 were included. Data were collected in November 2019 in five databases, based on the following search words: “enteral nutrition”, “palliative care” and “dementia”. After applying the inclusion criteria, 11 articles remained in the sample. The main findings of these publications were divided into three categories: “palliative care and care plan”, “palliative care and enteral nutrition” and “enteral nutrition in older adults with dementia”. The results call attention to the need for decision making to be based on scientific evidence.
DOI: 10.17632/wgrjmnbnpc.1
title: Structure-digestibility relationship from noodles based on organocatalytically esterified regular and waxy corn starch obtained by reactive extrusion using sodium propionate

description: These files provide the transparent date of this article.
DOI: 10.6084/m9.figshare.19905179
title: Enteral nutrition in older adults with dementia in palliative care

description: Abstract The number of older adults and, consequently, the incidence of chronic non-communicable diseases, including dementia, have increased exponentially. Dementia leads to progressive loss of functionality, including food-related complications. This article presents results of an integrative review on the current scientific evidence of enteral nutritional therapy in patients with dementia in palliative care. Articles published between 2009 and 2019 were included. Data were collected in November 2019 in five databases, based on the following search words: “enteral nutrition”, “palliative care” and “dementia”. After applying the inclusion criteria, 11 articles remained in the sample. The main findings of these publications were divided into three categories: “palliative care and care plan”, “palliative care and enteral nutrition” and “enteral nutrition in older adults with dementia”. The results call attention to the need for decision making to be based on scientific evidence.
DOI: 10.17632/cjmw72wbsw.1
title: Data for: Reactive extrusion-processed native and phosphated starch-based food packaging films governed by the hierarchical structure

description: These files provide the transparent date of this article.
DOI: 10.17632/9mpjnzp2hz.2
title: Data for: Are modified pumpkin flour/plum flour nanocomposite films biodegradable and compostable?

description: These files provide the transparent date of this article.