cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.9986351.v1
title: INSERTION OF THE FATHER IN THE CARE OF THE HOSPITALIZED PRETERM INFANT: PERCEPTION OF THE MULTIPROFESSIONAL TEAM

description: ABSTRACT Objective: To understand the perception of the multiprofessional health care team regarding the inclusion of fathers in the care of preterm infants who are in Intensive Care Units (ICUs). Methods: This is a descriptive study with a qualitative approach, using a semi-structured interview with 12 health care professionals of a neonatal ICU, from February to July 2017. The data were analyzed according to the Discourse of the Collective Subject. Results: Seven main ideas (MI) emerged from the text analysis, which were grouped into two themes: 1) the role of the father according to the multiprofessional health care team views (MI1: parent provider, MI2: shared care, MI3: supportive father); 2) perception of the father caring for the hospitalized preterm infant (MI4: father does not change diapers; MI5: father conquering new spaces; MI6: strengthening the bonding; MI7: father providing maternal security. Conclusions: The results of this study point out to the importance of including the father figure in the humanized care of preterm infants. Professional health care team should be more aware of fathers’ importance in the care of hospitalized preterm infants.
DOI: 10.6084/m9.figshare.9986351
title: INSERTION OF THE FATHER IN THE CARE OF THE HOSPITALIZED PRETERM INFANT: PERCEPTION OF THE MULTIPROFESSIONAL TEAM

description: ABSTRACT Objective: To understand the perception of the multiprofessional health care team regarding the inclusion of fathers in the care of preterm infants who are in Intensive Care Units (ICUs). Methods: This is a descriptive study with a qualitative approach, using a semi-structured interview with 12 health care professionals of a neonatal ICU, from February to July 2017. The data were analyzed according to the Discourse of the Collective Subject. Results: Seven main ideas (MI) emerged from the text analysis, which were grouped into two themes: 1) the role of the father according to the multiprofessional health care team views (MI1: parent provider, MI2: shared care, MI3: supportive father); 2) perception of the father caring for the hospitalized preterm infant (MI4: father does not change diapers; MI5: father conquering new spaces; MI6: strengthening the bonding; MI7: father providing maternal security. Conclusions: The results of this study point out to the importance of including the father figure in the humanized care of preterm infants. Professional health care team should be more aware of fathers’ importance in the care of hospitalized preterm infants.
DOI: 10.6084/m9.figshare.19980096
title: PEDIATRIC APPENDICITIS: AGE DOES MAKE A DIFFERENCE

description: ABSTRACT Objective: To investigate the influence of patient age on the diagnosis and management of appendicitis, as well as to evaluate the rate of complications according to the age group. Methods: We undertook a retrospective analysis of 1,736 children who underwent laparoscopic appendectomy in our center between January 2000 and December 2013. Patients were divided in groups taken into account their age: group A were infants, group B were preschoolers, group C were those ones older than five years old, and group D were those ones younger than five years old. A p value of 0.05 was considered statistically significant. Results: We found higher incidence of misdiagnosis and atypical symptoms in the youngest patients. The rate of perforation was similar between group A and B (p=0.17). However, it was higher in group D than in group C (p&lt;0.0001). The incidence of postoperative complications was higher in the youngest patients too (p=0.0002). Conclusions: The age does make a difference in acute appendicitis. Because of its unusual presentation in children younger than five years old, it is often misdiagnosed, which leads to an increased morbidity. Although clinical presentation varies between infants and preschoolers, no statistically significant differences were observed in the rate of perforated appendix or postoperative complications.
DOI: 10.6084/m9.figshare.19980096.v1
title: PEDIATRIC APPENDICITIS: AGE DOES MAKE A DIFFERENCE

description: ABSTRACT Objective: To investigate the influence of patient age on the diagnosis and management of appendicitis, as well as to evaluate the rate of complications according to the age group. Methods: We undertook a retrospective analysis of 1,736 children who underwent laparoscopic appendectomy in our center between January 2000 and December 2013. Patients were divided in groups taken into account their age: group A were infants, group B were preschoolers, group C were those ones older than five years old, and group D were those ones younger than five years old. A p value of 0.05 was considered statistically significant. Results: We found higher incidence of misdiagnosis and atypical symptoms in the youngest patients. The rate of perforation was similar between group A and B (p=0.17). However, it was higher in group D than in group C (p&lt;0.0001). The incidence of postoperative complications was higher in the youngest patients too (p=0.0002). Conclusions: The age does make a difference in acute appendicitis. Because of its unusual presentation in children younger than five years old, it is often misdiagnosed, which leads to an increased morbidity. Although clinical presentation varies between infants and preschoolers, no statistically significant differences were observed in the rate of perforated appendix or postoperative complications.
DOI: 10.6084/m9.figshare.9985730
title: CULTURAL ADAPTATION AND RELIABILITY ANALYSIS OF THE EARLY CLINICAL ASSESSMENT OF BALANCE

description: ABSTRACT Objective: To translate the Early Clinical Assessment of Balance (ECAB), an assessment scale developed specifically for children and adolescents with cerebral palsy into Brazilian Portuguese, evaluate semantic, idiomatic, experiential and conceptual equivalences, and to examine the face validity and the reliability within and between examiners of the Brazilian version. Methods: The following steps were done: translation by two independent translators; synthesis of translations; back translation into English; analysis of back-translations by a multidisciplinary committee and the author of the test to develop the final version of the test; test application training; administration of the translated version of ECAB (videotaped) in 60 children and adolescents with cerebral palsy; intra and inter-examiner reliability assessment. Reability was assessed by intraclass correlation coefficient (CCI). Results: The discrepancies found were related mainly to semantic equivalence and, therefore, there was no need to make cultural adaptations in any of the 13 items on the scale. The rate of agreement was greater than 90% and the reliability of the ECAB-Portuguese total score was excellent both for the intra-rater test (CCI=1.00) and for the inter-rater test (CCI=0.998). Likewise, the reliability evaluation of each of the scale items was also excellent. Conclusions: The translated version of the ECAB into Portuguese provides a tool for the evaluation of the specific balance for children and adolescents with cerebral palsy with different levels of functioning.
DOI: 10.6084/m9.figshare.9985730.v1
title: CULTURAL ADAPTATION AND RELIABILITY ANALYSIS OF THE EARLY CLINICAL ASSESSMENT OF BALANCE

description: ABSTRACT Objective: To translate the Early Clinical Assessment of Balance (ECAB), an assessment scale developed specifically for children and adolescents with cerebral palsy into Brazilian Portuguese, evaluate semantic, idiomatic, experiential and conceptual equivalences, and to examine the face validity and the reliability within and between examiners of the Brazilian version. Methods: The following steps were done: translation by two independent translators; synthesis of translations; back translation into English; analysis of back-translations by a multidisciplinary committee and the author of the test to develop the final version of the test; test application training; administration of the translated version of ECAB (videotaped) in 60 children and adolescents with cerebral palsy; intra and inter-examiner reliability assessment. Reability was assessed by intraclass correlation coefficient (CCI). Results: The discrepancies found were related mainly to semantic equivalence and, therefore, there was no need to make cultural adaptations in any of the 13 items on the scale. The rate of agreement was greater than 90% and the reliability of the ECAB-Portuguese total score was excellent both for the intra-rater test (CCI=1.00) and for the inter-rater test (CCI=0.998). Likewise, the reliability evaluation of each of the scale items was also excellent. Conclusions: The translated version of the ECAB into Portuguese provides a tool for the evaluation of the specific balance for children and adolescents with cerebral palsy with different levels of functioning.
DOI: 10.6084/m9.figshare.19979912
title: Haniffa TCR

description: TCR part of the Haniffa dataset. <br> Rehosting from https://www.ebi.ac.uk/arrayexpress/files/E-MTAB-10026/E-MTAB-10026.processed.2.zip <br> Source: https://www.nature.com/articles/s41591-021-01329-2
DOI: 10.6084/m9.figshare.19979912.v1
title: Haniffa TCR

description: TCR part of the Haniffa dataset. <br> Rehosting from https://www.ebi.ac.uk/arrayexpress/files/E-MTAB-10026/E-MTAB-10026.processed.2.zip <br> Source: https://www.nature.com/articles/s41591-021-01329-2
DOI: 10.6084/m9.figshare.9985982
title: PHYSICIANS’ KNOWLEDGE ABOUT PATIENTS’ RELIGIOUS BELIEFS IN PEDIATRIC CARE

description: ABSTRACT Objective: To describe the knowledge of pediatricians and pediatric residents about the meaning of death according to the most prevalent religions in Brazil. Methods: A cross-sectional survey was conducted among pediatricians and pediatric residents at a tertiary-level children’s hospital in the city of São Paulo, SP, Brazil, questioning about their knowledge and experience related to spiritual care and the most common religious beliefs among pediatric palliative care patients in Brazil. Results: 116 physicians answered the questionnaire, 98 (84.5%) considered themselves religious, defined as followers of any spiritual creed around the world, and 18 (15.5%) non-religious. Of the total, 97 (83.6%) considered themselves capable of dealing with the spiritual care of Catholic patients, 49 (42.2%) of Protestant patients and 92 (79.3%) of patients that follow Spiritism in the process of death. Religious doctors used less chaplaincy services than non-religious doctors (relative risk - RR 2.54; p=0.0432; confidence interval of 95% - 95%CI 1.21-5.34). Among the physicians, 111 (96%) believe that spirituality is beneficial in accepting the death process, responses were associated with the religiosity of the physicians (RR 1.18; p=0.0261; 95%CI 0.95-1.45). Also, 106 (91.4%) are unaware of the religion of their patients and the same number of participants consider pediatricians, in general, unprepared to deal with the spiritual aspect of death. These data are not associated with the participants’ religiosity. Conclusions: Although most pediatricians and residents consider themselves able to deal with the most prevalent religions in Brazil and affirm that spirituality is beneficial during the death process, little importance is given to the spiritual identity of their patients, which could limit an appropriate approach to their death process.
DOI: 10.6084/m9.figshare.9985982.v1
title: PHYSICIANS’ KNOWLEDGE ABOUT PATIENTS’ RELIGIOUS BELIEFS IN PEDIATRIC CARE

description: ABSTRACT Objective: To describe the knowledge of pediatricians and pediatric residents about the meaning of death according to the most prevalent religions in Brazil. Methods: A cross-sectional survey was conducted among pediatricians and pediatric residents at a tertiary-level children’s hospital in the city of São Paulo, SP, Brazil, questioning about their knowledge and experience related to spiritual care and the most common religious beliefs among pediatric palliative care patients in Brazil. Results: 116 physicians answered the questionnaire, 98 (84.5%) considered themselves religious, defined as followers of any spiritual creed around the world, and 18 (15.5%) non-religious. Of the total, 97 (83.6%) considered themselves capable of dealing with the spiritual care of Catholic patients, 49 (42.2%) of Protestant patients and 92 (79.3%) of patients that follow Spiritism in the process of death. Religious doctors used less chaplaincy services than non-religious doctors (relative risk - RR 2.54; p=0.0432; confidence interval of 95% - 95%CI 1.21-5.34). Among the physicians, 111 (96%) believe that spirituality is beneficial in accepting the death process, responses were associated with the religiosity of the physicians (RR 1.18; p=0.0261; 95%CI 0.95-1.45). Also, 106 (91.4%) are unaware of the religion of their patients and the same number of participants consider pediatricians, in general, unprepared to deal with the spiritual aspect of death. These data are not associated with the participants’ religiosity. Conclusions: Although most pediatricians and residents consider themselves able to deal with the most prevalent religions in Brazil and affirm that spirituality is beneficial during the death process, little importance is given to the spiritual identity of their patients, which could limit an appropriate approach to their death process.
DOI: 10.6084/m9.figshare.19980171
title: “BRUSH UP”: AN INNOVATIVE TECHNOLOGICAL AID FOR PARENTS TO KEEP A CHECK OF THEIR CHILDREN’S ORAL HYGIENE BEHAVIOUR

description: ABSTRACT Objective: To investigate the impact of “Brush Up” - a mobile application, on oral hygiene behaviours of 4-6-year-old children in Bangalore city. Methods: In this experimental study, 247 children aged 4-6, were randomly divided into three groups. Considering “Brush Up” is a mobile application, parents of the children in Group 1 (n=82) downloaded the application on their smartphones. Children in Group 2 (n=83) and Group 3 (n=82) received tooth brushing instructions by an educative video and manual demonstration, respectively. Effectiveness of tooth brushing was assessed with plaque scores, which were recorded for all the groups at baseline and one month using Visible Biofilm Index. Results: Wilcoxon signed rank test showed a significant improvement in the tooth brushing behaviour for the Brush Up group, which was indicated by a lower plaque score after a follow-up of one month. Kruskal-Wallis test followed by post-hoc test showed that the mean ranks of plaque scores of Brush Up group are consistently lower than those of video demonstration group and manual demonstration group. Conclusions: The lower plaque score in subsequent follow-up in Brush Up group suggests that using a smart system can enhance learning a correct tooth brushing method in young children and can also help in implementing the required reinforcement and motivation to brush and aid in better plaque control.
DOI: 10.6084/m9.figshare.19980171.v1
title: “BRUSH UP”: AN INNOVATIVE TECHNOLOGICAL AID FOR PARENTS TO KEEP A CHECK OF THEIR CHILDREN’S ORAL HYGIENE BEHAVIOUR

description: ABSTRACT Objective: To investigate the impact of “Brush Up” - a mobile application, on oral hygiene behaviours of 4-6-year-old children in Bangalore city. Methods: In this experimental study, 247 children aged 4-6, were randomly divided into three groups. Considering “Brush Up” is a mobile application, parents of the children in Group 1 (n=82) downloaded the application on their smartphones. Children in Group 2 (n=83) and Group 3 (n=82) received tooth brushing instructions by an educative video and manual demonstration, respectively. Effectiveness of tooth brushing was assessed with plaque scores, which were recorded for all the groups at baseline and one month using Visible Biofilm Index. Results: Wilcoxon signed rank test showed a significant improvement in the tooth brushing behaviour for the Brush Up group, which was indicated by a lower plaque score after a follow-up of one month. Kruskal-Wallis test followed by post-hoc test showed that the mean ranks of plaque scores of Brush Up group are consistently lower than those of video demonstration group and manual demonstration group. Conclusions: The lower plaque score in subsequent follow-up in Brush Up group suggests that using a smart system can enhance learning a correct tooth brushing method in young children and can also help in implementing the required reinforcement and motivation to brush and aid in better plaque control.
DOI: 10.6084/m9.figshare.18415520.v1
title: Stabilization of a Mn-Co oxide during oxygen evolution in alkaline media

description: Improving the stability of electrocatalysts for the oxygen evolution reaction (OER) through materials design has received less attention than improving their catalytic activity. We explored the effects of Mn addition to a cobalt oxide for stabilizing the catalyst by comparing single phase CoO<sub>x</sub> and (Co<sub>0.7</sub>Mn<sub>0.3</sub>)O<sub>x</sub> films electro­deposited in alkaline solution. The obtained disordered films were classified as layered oxides using X-ray absorption spectroscopy (XAS). The CoO<sub>x</sub> films showed a constant decrease in the catalytic activity during cycling, confirmed by oxygen detection, while that of (Co<sub>0.7</sub>Mn<sub>0.3</sub>)O<sub>x</sub> remained constant within error as measured by electrochemical metrics. These trends were rationalized based on XAS analysis of the metal oxidation states, which were Co<sup>2.7+</sup> and Mn<sup>3.7+</sup> in the bulk and similar near the surface of (Co<sub>0.7</sub>Mn<sub>0.3</sub>)O<sub>x</sub>, before and after cycling. Thus, Mn in (Co<sub>0.7</sub>Mn<sub>0.3</sub>)O<sub>x</sub> successfully stabilized the bulk catalyst material and its surface activity during OER cycling. The development of stabilization approaches is essential to extend the durability of OER catalysts.
DOI: 10.6084/m9.figshare.18415520
title: Stabilization of a Mn-Co oxide during oxygen evolution in alkaline media

description: Improving the stability of electrocatalysts for the oxygen evolution reaction (OER) through materials design has received less attention than improving their catalytic activity. We explored the effects of Mn addition to a cobalt oxide for stabilizing the catalyst by comparing single phase CoO<sub>x</sub> and (Co<sub>0.7</sub>Mn<sub>0.3</sub>)O<sub>x</sub> films electro­deposited in alkaline solution. The obtained disordered films were classified as layered oxides using X-ray absorption spectroscopy (XAS). The CoO<sub>x</sub> films showed a constant decrease in the catalytic activity during cycling, confirmed by oxygen detection, while that of (Co<sub>0.7</sub>Mn<sub>0.3</sub>)O<sub>x</sub> remained constant within error as measured by electrochemical metrics. These trends were rationalized based on XAS analysis of the metal oxidation states, which were Co<sup>2.7+</sup> and Mn<sup>3.7+</sup> in the bulk and similar near the surface of (Co<sub>0.7</sub>Mn<sub>0.3</sub>)O<sub>x</sub>, before and after cycling. Thus, Mn in (Co<sub>0.7</sub>Mn<sub>0.3</sub>)O<sub>x</sub> successfully stabilized the bulk catalyst material and its surface activity during OER cycling. The development of stabilization approaches is essential to extend the durability of OER catalysts.
DOI: 10.6084/m9.figshare.19980195
title: Elevated IgA and IL-10 levels in very-early-onset inflammatory bowel disease secondary to IL-10 receptor deficiency

description: ABSTRACT Objective: To report two patients with very-early-onset inflammatory bowel disease (VEOIBD) secondary to interleukin-10 receptor (IL-10R) mutations, explore immunophenotyping data and plasma cytokine profile on these cases compared to healthy controls, and describe the phenotype of IL-10/IL-10R mutations based on a literature review. Case description: We report on two female infants referred to our tertiary center at the age of ten months, with severe colonic and perianal disease, as well as significant malnutrition, who had shown limited response to usual inflammatory bowel disease (IBD) therapy agents. In the first case, whole-exome sequencing (WES) revealed a homozygous (c.537G&gt;A/p.T179T) mutation in exon 4 of the IL-10RA gene, while in the second patient, compound heterozygosity was identified, also in the IL-10RA gene (chr11:117.859.199 variant A&gt;G/p.Tyr57Cys and chr11: 117.860.335 variant G&gt;T/p.Val123Leu). Both patients underwent hematopoietic cell transplantation (HCT). Immunological work-up of these patients revealed increased IL-10 plasma levels and increased IgA. Comments: Our case reports disclose novel findings on plasma cytokine profile in IL-10R deficiency, and we describe the severe phenotype of IL-10/IL-10R deficiency that should be recognized by physicians.
DOI: 10.6084/m9.figshare.19980195.v1
title: Elevated IgA and IL-10 levels in very-early-onset inflammatory bowel disease secondary to IL-10 receptor deficiency

description: ABSTRACT Objective: To report two patients with very-early-onset inflammatory bowel disease (VEOIBD) secondary to interleukin-10 receptor (IL-10R) mutations, explore immunophenotyping data and plasma cytokine profile on these cases compared to healthy controls, and describe the phenotype of IL-10/IL-10R mutations based on a literature review. Case description: We report on two female infants referred to our tertiary center at the age of ten months, with severe colonic and perianal disease, as well as significant malnutrition, who had shown limited response to usual inflammatory bowel disease (IBD) therapy agents. In the first case, whole-exome sequencing (WES) revealed a homozygous (c.537G&gt;A/p.T179T) mutation in exon 4 of the IL-10RA gene, while in the second patient, compound heterozygosity was identified, also in the IL-10RA gene (chr11:117.859.199 variant A&gt;G/p.Tyr57Cys and chr11: 117.860.335 variant G&gt;T/p.Val123Leu). Both patients underwent hematopoietic cell transplantation (HCT). Immunological work-up of these patients revealed increased IL-10 plasma levels and increased IgA. Comments: Our case reports disclose novel findings on plasma cytokine profile in IL-10R deficiency, and we describe the severe phenotype of IL-10/IL-10R deficiency that should be recognized by physicians.
DOI: 10.6084/m9.figshare.19979828
title: Besnard_SupplTable1.xlsx

description: <strong>Supplementary Table 1. List of genes deleted in Mo’s affected heifers and human Jacobsen syndrome.</strong>
DOI: 10.6084/m9.figshare.19979828.v1
title: Besnard_SupplTable1.xlsx

description: <strong>Supplementary Table 1. List of genes deleted in Mo’s affected heifers and human Jacobsen syndrome.</strong>
DOI: 10.6084/m9.figshare.19979822.v1
title: Besnard_SupplTable2.xlsx

description: <strong>Supplementary Table 2. List of candidate variants for persistent </strong><em><strong>truncus arteriosus</strong></em><strong>.</strong>
DOI: 10.6084/m9.figshare.19979822
title: Besnard_SupplTable2.xlsx

description: <strong>Supplementary Table 2. List of candidate variants for persistent </strong><em><strong>truncus arteriosus</strong></em><strong>.</strong>
DOI: 10.57745/clnzyq/ohtj0n
title: Dataverse_Tracage Rampi 160316 RWT & AG.tab

description: :unav
DOI: 10.5517/ccdc.csd.cc2b507s
title: CCDC 2149764: Experimental Crystal Structure Determination

description: Related Article: Aaron Gabriel Nunez Avila, Benoît Deschênes Simard, Joseph E. Arnold, Mathieu Morency, Daniel Chartrand, Thierry Maris, Gilles Berger, Graeme M. Day, Stephen Hanessian, James D. Wuest|2022|J.Org.Chem.|87|6680|doi:10.1021/acs.joc.2c00369
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.