cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.3581766
title: Heterogeneity of studies in anesthesiology meta-analyses: A meta-epidemiological review and proposal for evidence mapping.xlsx

description: <b>Background</b> Heterogeneity among the primary studies included in a systematic review is one of the most challenging considerations for systematic reviewers. Current practices in anesthesiology systematic reviews have not been evaluated, but traditional methods may not provide sufficient information to evaluate the true nature of these differences. We address these issues by examining the practices of systematic reviewers for evaluating heterogeneity in anesthesiology reviews. We also propose a mapping method for presenting heterogeneous aspects of the primary studies in systematic reviews. <b>Methods</b> We evaluated heterogeneity practices reported in systematic reviews published in highly ranked anesthesiology journals. Elements extracted from the SRs included heterogeneity tests, models used, analyses conducted, plots used to display heterogeneity, and significant p-values. We also extracted all I<sup>2</sup> values from the SRs to quantify the level of heterogeneity. Additionally, we selected a systematic review develop an evidence map in order to display clinical heterogeneity. <b>Results</b> Our statistical analysis showed 150/207 SRs reporting a test for statistical heterogeneity. Of the 150 SRs, 138 reported the use of a plot to display statistical heterogeneity. Subgroup analyses were the most commonly reported analysis (54%). Meta-regression and sensitivity analyses were used sparingly (25%; 23% respectively). A random effects model was most commonly reported (33%); however, most SRs did not report this information (38%). Heterogeneity statistics across meta-analyses suggested that, in our sample, the majority (55%) did not present sufficient heterogeneity to be of great concern. <b>Conclusions</b> Many reviews did not provide sufficient detail regarding heterogeneity. We are calling for improvement to reporting practices.
DOI: 10.6084/m9.figshare.3581766.v1
title: Figshare data Heterogeneity.xlsx

description: <b>Background</b> Heterogeneity among the primary studies included in a systematic review is one of the most challenging considerations for systematic reviewers. Current practices in anesthesiology systematic reviews have not been evaluated, but traditional methods may not provide sufficient information to evaluate the true nature of these differences. We address these issues by examining the practices of systematic reviewers for evaluating heterogeneity in anesthesiology reviews. We also propose a mapping method for presenting heterogeneous aspects of the primary studies in systematic reviews. <b>Methods</b> We evaluated heterogeneity practices reported in systematic reviews published in highly ranked anesthesiology journals. Elements extracted from the SRs included heterogeneity tests, models used, analyses conducted, plots used to display heterogeneity, and significant p-values. We also extracted all I<sup>2</sup> values from the SRs to quantify the level of heterogeneity. Additionally, we selected a systematic review develop an evidence map in order to display clinical heterogeneity. <b>Results</b> Our statistical analysis showed 150/207 SRs reporting a test for statistical heterogeneity. Of the 150 SRs, 138 reported the use of a plot to display statistical heterogeneity. Subgroup analyses were the most commonly reported analysis (54%). Meta-regression and sensitivity analyses were used sparingly (25%; 23% respectively). A random effects model was most commonly reported (33%); however, most SRs did not report this information (38%). Heterogeneity statistics across meta-analyses suggested that, in our sample, the majority (55%) did not present sufficient heterogeneity to be of great concern. <b>Conclusions</b> Many reviews did not provide sufficient detail regarding heterogeneity. We are calling for improvement to reporting practices.
DOI: 10.6084/m9.figshare.3581739
title: Discutindo Bioética e Anos 1960

description: A brief presentation of the scientific, social and cultural contributions from the 1960s to stablish the roots of contemporary Bioethics.
DOI: 10.6084/m9.figshare.3581739.v1
title: Discutindo Bioética e Anos 1960

description: A brief presentation of the scientific, social and cultural contributions from the 1960s to stablish the roots of contemporary Bioethics.
DOI: 10.6084/m9.figshare.3581616
title: Time Series Meta-Analysis Files

description: Data files, notes and ipython notebook from gut time series meta analysis by Gibbons et al., 2016.<br>
DOI: 10.6084/m9.figshare.3581616.v2
title: Time Series Meta-Analysis Files

description: Data files, notes and ipython notebook from gut time series meta analysis by Gibbons et al., 2016.<br>
DOI: 10.6084/m9.figshare.3581616.v1
title: Time Series Meta-Analysis Files

description: Data files, notes and ipython notebook from gut time series meta analysis by Gibbons et al., 2016.<br>
DOI: 10.6084/m9.figshare.3581598
title: Multi-fasta file of variable SNP positions in 2000+ Staphylococcus aureus genomes

description: N315 is the reference strain. Each genome downloaded from NCBI SRA and aligned using BWA. SNPs called using GCAT.
DOI: 10.6084/m9.figshare.3581598.v2
title: Multi-fasta file of variable SNP positions in 2000+ Staphylococcus aureus genomes

description: N315 is the reference strain. Each genome downloaded from NCBI SRA and aligned using BWA. SNPs called using GCAT.
DOI: 10.6084/m9.figshare.3581598.v1
title: aligned_subtyping_strains.fasta

description: Multi-fasta file of variable SNP positions 2000+ Staphylococcus aureus genomes
DOI: 10.6084/m9.figshare.3581481
title: Flashy females shed light on reciprocal nature of courtship in frogs

description: We examined courtship behaviour of 15–20 females from each of four populations of red-eyed treefrogs. We measured mating behaviour using a no-choice experimental design. Females were tested in three 10-min trials in which she was presented, in random order, with a model from the local or one of two non-local populations. We recorded the occurrence of back and/or flank displays and time invested in flank display. Due to the uniformly short duration of back displays (&lt;3 s), we did not measure duration for this trait. We recorded the advertisement calls of 12–22 males from each of six populations of red-eyed treefrogs. We determined the dominant frequency and the interquartile range bandwidth (bandwidth; the frequency range containing the middle 50% of sound energy) using Raven 1.4.We also include data from mate choice trials conducted by Jacobs et al. in 2013 using live males and females. For methods, see: Jacobs, L. E., Vega, A., Dudgeon, S., Kaiser, K., & Robertson, J. M. (2016). Local not vocal: assortative female choice in divergent populations of red‐eyed treefrogs, Agalychnis callidryas (Hylidae: Phyllomedusinae). <i>Biological Journal of the Linnean Society</i>.<br>
DOI: 10.6084/m9.figshare.3581481.v1
title: Male and female courtship signals constitute local dialects in red-eyed treefrogs

description: We examined courtship behaviour of 15–20 females from each of four populations of red-eyed treefrogs. We measured mating behaviour using a no-choice experimental design. Females were tested in three 10-min trials in which she was presented, in random order, with a model from the local or one of two non-local populations. We recorded the occurrence of back and/or flank displays and time invested in flank display. Due to the uniformly short duration of back displays (&lt;3 s), we did not measure duration for this trait. We recorded the advertisement calls of 12–22 males from each of six populations of red-eyed treefrogs. We determined the dominant frequency and the interquartile range bandwidth (bandwidth; the frequency range containing the middle 50% of sound energy) using Raven 1.4.
DOI: 10.6084/m9.figshare.3581481.v3
title: Flashy females shed light on reciprocal nature of courtship in frogs

description: We examined courtship behaviour of 15–20 females from each of four populations of red-eyed treefrogs. We measured mating behaviour using a no-choice experimental design. Females were tested in three 10-min trials in which she was presented, in random order, with a model from the local or one of two non-local populations. We recorded the occurrence of back and/or flank displays and time invested in flank display. Due to the uniformly short duration of back displays (&lt;3 s), we did not measure duration for this trait. We recorded the advertisement calls of 12–22 males from each of six populations of red-eyed treefrogs. We determined the dominant frequency and the interquartile range bandwidth (bandwidth; the frequency range containing the middle 50% of sound energy) using Raven 1.4.We also include data from mate choice trials conducted by Jacobs et al. in 2013 using live males and females. For methods, see: Jacobs, L. E., Vega, A., Dudgeon, S., Kaiser, K., & Robertson, J. M. (2016). Local not vocal: assortative female choice in divergent populations of red‐eyed treefrogs, Agalychnis callidryas (Hylidae: Phyllomedusinae). <i>Biological Journal of the Linnean Society</i>.<br>
DOI: 10.6084/m9.figshare.3581481.v2
title: Flashy females shed light on reciprocal nature of courtship in frogs

description: We examined courtship behaviour of 15–20 females from each of four populations of red-eyed treefrogs. We measured mating behaviour using a no-choice experimental design. Females were tested in three 10-min trials in which she was presented, in random order, with a model from the local or one of two non-local populations. We recorded the occurrence of back and/or flank displays and time invested in flank display. Due to the uniformly short duration of back displays (&lt;3 s), we did not measure duration for this trait. We recorded the advertisement calls of 12–22 males from each of six populations of red-eyed treefrogs. We determined the dominant frequency and the interquartile range bandwidth (bandwidth; the frequency range containing the middle 50% of sound energy) using Raven 1.4.
DOI: 10.6084/m9.figshare.3581457
title: Predictors of stamina in dogs exercising exercising in high ambient temperatures

description: This data set was collected from a canine exercise study looking at predictors of stamina during exercise in high ambient temperatures. The exercise consisted of search, agility, and ball retrieve. Measurements collected include core body temperature, pulse rate, left and right ear temperature, and hematological values.
DOI: 10.6084/m9.figshare.3581457.v1
title: StaminaManuscriptData.xlsx

description: This data set was collected from a canine exercise study looking at predictors of stamina during exercise in high ambient temperatures. The exercise consisted of search, agility, and ball retrieve. Measurements collected include core body temperature, pulse rate, left and right ear temperature, and hematological values.
DOI: 10.6084/m9.figshare.3581436
title: A Centrifugation-based Physicochemical Characterization Method for the Interaction between Proteins and Nanoparticles

description: Raw data of analytical ultracentrifugation experiments
DOI: 10.6084/m9.figshare.3581436.v1
title: A Centrifugation-based Physicochemical Characterization Method for the Interaction between Proteins and Nanoparticles

description: Raw data of analytical ultracentrifugation experiments
DOI: 10.17632/gjjwbwb895.1
title: Geochemical Discrimination of Igneous Zircon in the Gawler Craton, South Australia

description: Whole rock geochemical data and zircon trace and rare earth element chemistry for unaltered igneous suites in the Gawler Craton, South Australia.
DOI: 10.6084/m9.figshare.3581403
title: Burkina Faso study materials

description: Baseline dataset and IRB Protocol for the Burkina Faso study
DOI: 10.6084/m9.figshare.3581403.v1
title: Burkina Faso study dataset

description: Baseline dataset for the Burkina Faso study
DOI: 10.6084/m9.figshare.3581403.v2
title: Burkina Faso study dataset

description: Baseline dataset and IRB Protocol for the Burkina Faso study
DOI: 10.21223/9qlh89/uodptr
title: 13202_data_dictionary.tab
DOI: 10.21223/9qlh89/8qrcmw
title: 13202_data_viroma_potato_Burundi_2018.tab
DOI: 10.17632/mg2x8kd49w.1
title: Data-Wei Guo

description: The raw data of XRD, nanoindentation value for equiatomic CrMnFeCoNi high entropy alloy
DOI: 10.21223/9qlh89/v03iob
title: 13202_data_documentation.tab
DOI: 10.21223/9qlh89/uo0irn
title: 13202_data_documentation.tab
DOI: 10.21223/9qlh89/jxwdau
title: 13202_data_viroma_potato_Burundi_2018.tab
DOI: 10.21223/9qlh89/fqds97
title: 13202_data_dictionary.tab
DOI: 10.21223/9qlh89
title: Dataset for: Virus biodiversity: Determination of virus variability in potato and sweetpotato from Lake Kivu region (i.e. samples from potato-Burundi, sweetpotato-Rwanda)

description: The new data set of Virus biodiversity: Molecular information of the viral sequences (viroma) has been generated in representative potato samples collected in selected cultivated fields in Burundi. For this, the sequencing and assembly of small interfering RNAs (sRSA) was used, which is a modern diagnostic method developed by the CIP. sRSA is a generic diagnostic method that allows to detect all viruses (known and not yet discovered / new) in a single test, so it is considered a revolutionary diagnostic method. The information resulting from the project will make it possible to better understand the diversity of potato viruses, guarantee the control of established, emerging and exotic viral diseases that allow a rapid and reliable integral response to the risks faced by Africa due to global warming.
DOI: 10.6084/m9.figshare.3581253
title: Streamlining Assessment Exercises and Faculty Activity Reviews

description: A presentation given by Jonathan Breeze, Symplectic at the VIVO 2016 conference in Denver, CO.<br><br>Abstract: Ask a researcher to populate an institutional webpage and you’ll see them roll their eyes and move on to something more enjoyable. Ask a researcher to complete their faculty activity report and they'll grudgingly do it, but complain about the duplicated effort. However: ask a researcher to keep a system up-to-date throughout the year, so that they can avoid the annual form-filling common with other systems, and they might not only do it, but tell their colleagues about how easy it was! One of the core concepts behind Symplectic’s mission is the reduction of the administrative burden from research institutions and their staff. The next logical step in this calling is the tackling of faculty activity and performance-related assessments: parts of a much larger data- gathering exercise that institutions partake in every year and one that remains laborious to all required to contribute. The latest major release of Elements, Symplectic’s leading Research Information Management System, contained a highly-anticipated solution to this issue - the Assessment Module. Assessment-related data can now be reused, repurposed, and resurfaced on a VIVO profile, with researchers having the freedom to pick what’s pertinent for public use. This presentation will explore how this module offers a significant new repurpose of institutional data. Complementing our long-standing relationship with VIVO, Symplectic is continually committed to semantically linking previously siloed data; knowing that this data is only useful when it can be reused throughout an institution freeing faculty from burdensome reentry.
DOI: 10.6084/m9.figshare.3581253.v1
title: Streamlining Assessment Exercises and Faculty Activity Reviews

description: A presentation given by Jonathan Breeze, Symplectic at the VIVO 2016 conference in Denver, CO.<br><br>Abstract: Ask a researcher to populate an institutional webpage and you’ll see them roll their eyes and move on to something more enjoyable. Ask a researcher to complete their faculty activity report and they'll grudgingly do it, but complain about the duplicated effort. However: ask a researcher to keep a system up-to-date throughout the year, so that they can avoid the annual form-filling common with other systems, and they might not only do it, but tell their colleagues about how easy it was! One of the core concepts behind Symplectic’s mission is the reduction of the administrative burden from research institutions and their staff. The next logical step in this calling is the tackling of faculty activity and performance-related assessments: parts of a much larger data- gathering exercise that institutions partake in every year and one that remains laborious to all required to contribute. The latest major release of Elements, Symplectic’s leading Research Information Management System, contained a highly-anticipated solution to this issue - the Assessment Module. Assessment-related data can now be reused, repurposed, and resurfaced on a VIVO profile, with researchers having the freedom to pick what’s pertinent for public use. This presentation will explore how this module offers a significant new repurpose of institutional data. Complementing our long-standing relationship with VIVO, Symplectic is continually committed to semantically linking previously siloed data; knowing that this data is only useful when it can be reused throughout an institution freeing faculty from burdensome reentry.
DOI: 10.6084/m9.figshare.3581244
title: Analysis of enhancement at small and large radiation doses for effectiveness of inactivation in cultured cells by combining two agents with radiation

description: <b>Purpose:</b> To evaluate the enhancement effect of two combined radiation-sensitizing agents in mammalian cells at small doses as compared to large doses using the linear-quadratic (LQ) mathematical model. <b>Methods and materials:</b> Data on clonogenic assays concerning the radio-enhancement effects of combined halogenated pyrimidines and hyperthermia or combined cisplatin and hyperthermia, as published in earlier reports, were analyzed according to the LQ-formula: S(D)/S(0) = exp−(αD + βD<sup>2</sup>). Effects of sensitizing agents on the linear parameter α and the quadratic parameter β are compared in order to evaluate differences depending on the applied dose, the possible relations to mechanisms of radiation sensitization and to derive suggestions for applications. <b>Results:</b> The values of the linear parameter α, which determines the effectiveness at low doses, are for all cell lines and all conditions more increased than the values of the parameter β which has a higher contribution at larger radiation doses. The combination of hyperthermia with halogenated pyrimidines to radiation as well as the combination of hyperthermia and cisplatin to radiation significantly increases the value of the linear parameter α, as compared to radiation alone or radiation combined with a single agent. <b>Conclusions:</b> The radiation enhancement factors of the values of linear and quadratic parameters demonstrate that the sensitizing agents have a larger effect on the linear parameter which is dominant at low radiation doses as is used in fractionated-radiation treatment in the clinic. Moreover, the effect is even further increased when two radiation sensitizers are used.
DOI: 10.6084/m9.figshare.3581244.v1
title: Analysis of enhancement at small and large radiation doses for effectiveness of inactivation in cultured cells by combining two agents with radiation

description: <b>Purpose:</b> To evaluate the enhancement effect of two combined radiation-sensitizing agents in mammalian cells at small doses as compared to large doses using the linear-quadratic (LQ) mathematical model. <b>Methods and materials:</b> Data on clonogenic assays concerning the radio-enhancement effects of combined halogenated pyrimidines and hyperthermia or combined cisplatin and hyperthermia, as published in earlier reports, were analyzed according to the LQ-formula: S(D)/S(0) = exp−(αD + βD<sup>2</sup>). Effects of sensitizing agents on the linear parameter α and the quadratic parameter β are compared in order to evaluate differences depending on the applied dose, the possible relations to mechanisms of radiation sensitization and to derive suggestions for applications. <b>Results:</b> The values of the linear parameter α, which determines the effectiveness at low doses, are for all cell lines and all conditions more increased than the values of the parameter β which has a higher contribution at larger radiation doses. The combination of hyperthermia with halogenated pyrimidines to radiation as well as the combination of hyperthermia and cisplatin to radiation significantly increases the value of the linear parameter α, as compared to radiation alone or radiation combined with a single agent. <b>Conclusions:</b> The radiation enhancement factors of the values of linear and quadratic parameters demonstrate that the sensitizing agents have a larger effect on the linear parameter which is dominant at low radiation doses as is used in fractionated-radiation treatment in the clinic. Moreover, the effect is even further increased when two radiation sensitizers are used.
DOI: 10.6084/m9.figshare.3581235
title: Code and data for "A rigorous statistical framework for estimating the long-term health impact of air pollution"

description: This folder contains code and data necessary to fit the models documented in Section 4 of the paper "A rigorous statistical framework for estimating the long-term health impact of air pollution".<br><br>The code is a mixture of C and R and is run from the file MAIN.R where more specific instructions can be found.<br>
DOI: 10.6084/m9.figshare.3581199
title: XMetDB database dump as of 20160815 - an open database for xenobiotic metabolism

description: Database dump for XMetDB (www.xmetdb.org); an open access and open source database and web interface for the submission and retrieval of experimental metabolite data for drugs and other xenobiotics.
DOI: 10.6084/m9.figshare.3581199.v1
title: xmetdb-20160815.sql

description: Database dump for XMetDB (www.xmetdb.org); an open access and open source database and web interface for the submission and retrieval of experimental metabolite data for drugs and other xenobiotics.
DOI: 10.6084/m9.figshare.3581199.v3
title: XMetDB database dump as of 20160815 - an open database for xenobiotic metabolism

description: Database dump for XMetDB (www.xmetdb.org); an open access and open source database and web interface for the submission and retrieval of experimental metabolite data for drugs and other xenobiotics.
DOI: 10.6084/m9.figshare.3581199.v2
title: Database dump of XMetDB 20160815 - an open database for xenobiotic metabolism

description: Database dump for XMetDB (www.xmetdb.org); an open access and open source database and web interface for the submission and retrieval of experimental metabolite data for drugs and other xenobiotics.