cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.1273746
title: Structure Of Complement C3(H2O) Revealed By Quantitative Cross-Linking/Mass Spectrometry And Modeling

description: The slow but spontaneous and ubiquitous formation of C3(H2O), the hydrolytic and conformationally rearranged product of C3, initiates antibody-independent activation of the complement system that is a key first line of antimicrobial defense. The structure of C3(H2O) has not been determined. Here we subjected C3(H2O) to quantitative cross-linking/mass spectrometry (QCLMS). This revealed details of the structural differences and similarities between C3(H2O) and C3, as well as between C3(H2O) and its pivotal proteolytic cleavage product, C3b, which shares functionally similarity with C3(H2O). Considered in combination with the crystal structures of C3 and C3b, the QCMLS data suggest that C3(H2O) generation is accompanied by the migration of the thioester-containing domain of C3 from one end of the molecule to the other. This creates a stable C3b-like platform able to bind the zymogen, factor B, or the regulator, factor H. Integration of available crystallographic and QCLMS data allowed the determination of a 3D model of the C3(H2O) domain architecture. The unique arrangement of domains thus observed in C3(H2O), which retains the anaphylatoxin domain (that is excised when C3 is enzymatically activated to C3b), can be used to rationalize observed differences between C3(H2O) and C3b in terms of complement activation and regulation.

<strong>For more information</strong> about how to reproduce this modeling, see the Sali lab website or the README file.
DOI: 10.5281/zenodo.598124
title: Structure Of Complement C3(H2O) Revealed By Quantitative Cross-Linking/Mass Spectrometry And Modeling

description: The slow but spontaneous and ubiquitous formation of C3(H2O), the hydrolytic and conformationally rearranged product of C3, initiates antibody-independent activation of the complement system that is a key first line of antimicrobial defense. The structure of C3(H2O) has not been determined. Here we subjected C3(H2O) to quantitative cross-linking/mass spectrometry (QCLMS). This revealed details of the structural differences and similarities between C3(H2O) and C3, as well as between C3(H2O) and its pivotal proteolytic cleavage product, C3b, which shares functionally similarity with C3(H2O). Considered in combination with the crystal structures of C3 and C3b, the QCMLS data suggest that C3(H2O) generation is accompanied by the migration of the thioester-containing domain of C3 from one end of the molecule to the other. This creates a stable C3b-like platform able to bind the zymogen, factor B, or the regulator, factor H. Integration of available crystallographic and QCLMS data allowed the determination of a 3D model of the C3(H2O) domain architecture. The unique arrangement of domains thus observed in C3(H2O), which retains the anaphylatoxin domain (that is excised when C3 is enzymatically activated to C3b), can be used to rationalize observed differences between C3(H2O) and C3b in terms of complement activation and regulation.

<strong>For more information</strong> about how to reproduce this modeling, see the Sali lab website or the README file.
DOI: 10.5517/ccdc.csd.cc1yyg6k
title: CCDC 1815769: Experimental Crystal Structure Determination

description: Related Article: Huijun Liu, Jiajie Zeng, Jingjing Guo, Han Nie, Zujin Zhao, Ben Zhong Tang|2018|Angew.Chem.,Int.Ed.|57|9290|doi:10.1002/anie.201802060
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc1z1z55
title: CCDC 1819147: Experimental Crystal Structure Determination

description: Related Article: Sadeh Sadeh, My P. T. Cao, J. Wilson Quail, Jianfeng Zhu, Jens Müller|2018|Chem.-Eur.J.|24|8298|doi:10.1002/chem.201801139
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc1z1z66
title: CCDC 1819148: Experimental Crystal Structure Determination

description: Related Article: Sadeh Sadeh, My P. T. Cao, J. Wilson Quail, Jianfeng Zhu, Jens Müller|2018|Chem.-Eur.J.|24|8298|doi:10.1002/chem.201801139
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc1p0dhl
title: CCDC 1549519: Experimental Crystal Structure Determination

description: Related Article: Viktor Bezborodov, Ilya Babenko, Igor Rozentsveig, Nikolay Korchevin, Ekaterina Levanova, Vladimir Smirnov, Tatyana Borodina, Vitaliy Saraev, Alexey Vilms|2018|Polyhedron|151|287|doi:10.1016/j.poly.2018.05.053
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc1q2gcm
title: CCDC 1581290: Experimental Crystal Structure Determination

description: Related Article: Kehan Xu, Shaosheng He, Shichao Chen, Guoliang Qiu, Jingbo Shi, Xinhua Liu, Xiaoyu Wu, Jing Zhang, Wenjian Tang|2018|Eur.J.Med.Chem.|154|144|doi:10.1016/j.ejmech.2018.05.021
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.15151/esrf-es-102584455
title: Macromolecular crystallography at the Philipps University Marburg (MarBAG)
DOI: 10.17632/r84ztskjwf.1
title: Data for: Comparison of different chemical cleaning reagents on fouling recovery in a self-forming dynamic membrane bioreactor (SFDMBR)

description: This document only includes the SFDMBR performance data.
DOI: 10.5523/bris.6a34adi090bo27ds5kkm5y9h5
title: Data from The Condensation Kinetics of Water on Amorphous Aerosol Particles (JPC Letters, 2018)

description: Aerosol particles can exist as solution droplets, viscous semi-solids, glasses or crystalline solids. Responding to changes in the surrounding gas phase environment, particles can grow by water condensation changing rapidly in composition and, possibly, changing dramatically in viscosity. The timescale for condensational growth is important to establish for particles undergoing processes in the atmosphere or during inhalation. Here, we report direct measurements of the timescales for condensational growth on a range of model aerosol systems extending from viscous aerosol particles containing a single saccharide solute (sucrose, glucose, raffinose or trehalose) and a starting viscosity equivalent to a glass of ~1012 Pa s, through to non-viscous sodium nitrate or tetraethylene glycol particles. Measurements are reported at -7.5, 0 and 20 oC using an electrodynamic balance for particles of initial size ~8-10 m.  Overall, the condensation timescales observed in this work indicate that water condensation occurs rapidly at all temperatures examined (&lt; 10 s) and for particles of all initial viscosities spanning 10-2 to 1012 Pa·s, with only a marginal delay (&lt;1 order of magnitude) for particles starting as a glass. This conclusion is significant for both cloud formation processes (droplets &lt; 1 μm should track changes in gas phase RH) and inhalation formulations (droplets &gt; 1 μm may require longer timescales for equilibration than inhalation).
DOI: 10.5281/zenodo.1270328
title: Data Supplementing Article "Estuarine Circulation In A Shallow But Stratified Estuary: Different Responses To River Discharge Between Deep Ship Channel And Shoals" Submitted To Journal Of Geophysical Research: Oceans

description: The dataset uploaded includes the measured salinity and velocity at two monitoring stations (one at the lower Mobile Bay and the other at the eastern edge of ship channel in middle Mobile Bay) and from multiple ship cruises crossing the lower, middle, and upper Mobile Bay. 

Detail information on the measurement frequency, date, and location can be found in the mat files.  Records with bad quality are filled with NaN values.
DOI: 10.5281/zenodo.1270329
title: Data Supplementing Article "Estuarine Circulation In A Shallow But Stratified Estuary: Different Responses To River Discharge Between Deep Ship Channel And Shoals" Submitted To Journal Of Geophysical Research: Oceans

description: The dataset uploaded includes the measured salinity and velocity at two monitoring stations (one at the lower Mobile Bay and the other at the eastern edge of ship channel in middle Mobile Bay) and from multiple ship cruises crossing the lower, middle, and upper Mobile Bay. 

Detail information on the measurement frequency, date, and location can be found in the mat files.  Records with bad quality are filled with NaN values.
DOI: 10.5281/zenodo.1270382
title: The Process Of Hdac11 Assay Development: Linearity And Km Calculation

description: With previously optimized conditions, the linearity range for HDAC11 was obtained and the Km for the substrate was calculated.

 

<strong>Note: </strong>1. In the assay buffer, BSA conc. is 0.5 mg/ml (instead of 0.5%).

          2. In the 7.5 ul developer solution, 40 uM of TSA (Trichostatin A) is also included.
description: The SGC is a registered charity (number 1097737) that receives funds from AbbVie, Bayer Pharma AG, Boehringer Ingelheim, Canada Foundation for Innovation, Eshelman Institute for Innovation, Genome Canada through Ontario Genomics Institute [OGI-055], Innovative Medicines Initiative (EU/EFPIA) [ULTRA-DD grant no. 115766], Janssen, Merck KGaA, Darmstadt, Germany, MSD, Novartis Pharma AG, Ontario Ministry of Research, Innovation and Science (MRIS), Pfizer, São Paulo Research Foundation-FAPESP, Takeda, and Wellcome.
DOI: 10.5281/zenodo.1270383
title: The Process Of Hdac11 Assay Development: Linearity And Km Calculation

description: With previously optimized conditions, the linearity range for HDAC11 was obtained and the Km for the substrate was calculated.

 

<strong>Note: </strong>1. In the assay buffer, BSA conc. is 0.5 mg/ml (instead of 0.5%).

          2. In the 7.5 ul developer solution, 40 uM of TSA (Trichostatin A) is also included.
description: The SGC is a registered charity (number 1097737) that receives funds from AbbVie, Bayer Pharma AG, Boehringer Ingelheim, Canada Foundation for Innovation, Eshelman Institute for Innovation, Genome Canada through Ontario Genomics Institute [OGI-055], Innovative Medicines Initiative (EU/EFPIA) [ULTRA-DD grant no. 115766], Janssen, Merck KGaA, Darmstadt, Germany, MSD, Novartis Pharma AG, Ontario Ministry of Research, Innovation and Science (MRIS), Pfizer, São Paulo Research Foundation-FAPESP, Takeda, and Wellcome.
DOI: 10.5445/ir/1000082997
title: Cloud top phase distributions of simulated deep convective clouds
DOI: 10.5281/zenodo.1260446
title: Combat-Tb Genome Annotation Graph Database

description: The Neo4J graph database containing annotation related to the M. tuberculosis H37Rv genome, created as part of the COMBAT TB project at the South African National Bioinformatics Institute (SANBI).
description: -  Updated rRNAs and GO Terms
- Added H37RV UNIPROT CSV
DOI: 10.5281/zenodo.1283382
title: Asvs, Taxonomy & Metadata

description: Amplicon sequence variants (ASVs) and associated taxonomy called using DADA2 (v1.6.0) and Silva 16S database v132, along with anonymized specimen metadata.

File list:


	<strong>Specimen_Table.csv</strong>: contains specimen type, subject id, and study day for each specimen collected. Some specimens have data on antibiotics administered that day in the "abx_b" column.
	<strong>seqtab.rds</strong>: ASVs for each specimen (rownames correlate to specimen_id2 in specimen table)
	<strong>taxa.rds</strong>: taxonomic assignments for each ASV in seqtab.rds
DOI: 10.5281/zenodo.1283383
title: 16S Amplicon Sequence Variance + Taxonomy

description: Amplicon sequence variants (ASVs) and associated taxonomy called using DADA2 (v1.6.0) and Silva 16S database v132.
DOI: 10.17632/jvpxdt6frp.1
title: Data for: Accessibility Analysis for Transportation Projects and Plans

description: Summary files contain 2010 actual and 2020 forecast land use patterns, including household counts (HH) and employment counts (EMP) by Census Tract. Also included is the accessibility to jobs of each Census Tract (ACCESS). Change in households, employment, and accessibility between build and no build scenarios are included for convenience (DIFF variables). The impedance files are the zone-to-zone travel times by auto during the peak hour used as inputs to the TELUM 2010 land use model. For the Loop 1604 projects, there is only 2010 and 2020 travel times; for the Mobility 2040 projects, there is also 2015 travel times provided.
DOI: 10.5517/ccdc.csd.cc1mpsgk
title: CCDC 1510489: Experimental Crystal Structure Determination

description: Related Article: Aline Nonat, Tao Liu, Olivier Jeannin, Franck Camerel, Loïc J. Charbonnière|2018|Chem.-Eur.J.|24|3784|doi:10.1002/chem.201705532
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc1mpshl
title: CCDC 1510490: Experimental Crystal Structure Determination

description: Related Article: Aline Nonat, Tao Liu, Olivier Jeannin, Franck Camerel, Loïc J. Charbonnière|2018|Chem.-Eur.J.|24|3784|doi:10.1002/chem.201705532
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.17032/shu-180003
title: An acute bout of cycling does not induce compensatory responses in pre-menopausal women not using hormonal contraceptives

description: There is a clear need to improve understanding of the effects of physical activity and exercise on appetite control. Therefore, the acute and short-term effects (three days) of a single bout of cycling on energy intake and energy expenditure were examined in women not using hormonal contraceptives. Sixteen active (n = 8) and inactive (n = 8) healthy pre-menopausal women completed a randomised crossover design study with two conditions (exercise and control). The exercise day involved cycling for one hour (50% of maximum oxygen uptake) and resting for two hours, whilst the control day comprised three hours of rest. On each experimental day participants arrived at the laboratory fasted, consumed a standardised breakfast and an ad libitum pasta lunch. Food diaries and combined heart rate-accelerometer monitors were used to assess free-living food intake and energy expenditure, respectively, over the subsequent three days. There were no main effects or condition (exercise vs control) by group (active vs inactive) interaction for absolute energy intake (P &gt; 0.05) at the ad libitum laboratory lunch meal, but there was a condition effect for relative energy intake (P = 0.004, ηp2 = 0.46) that was lower in the exercise condition (1417 ± 926 kJ vs. 2120 ± 923 kJ). Furthermore, post-breakfast satiety was higher in the active than in the inactive group (P = 0.005, ηp2 = 0.44). There were no main effects or interactions (P &gt; 0.05) for mean daily energy intake, but both active and inactive groups consumed less energy from protein (14 ± 3% vs. 16 ± 4%, P = 0.016, ηp2 = 0.37) and more from carbohydrate (53 ± 5% vs. 49 ± 7%, P = 0.031, ηp2 = 0.31) following the exercise condition. This study suggests that an acute bout of cycling does not induce compensatory responses in active and inactive women not using hormonal contraceptives, while the stronger satiety response to the standardised breakfast meal in active individuals adds to the growing literature that physical activity helps improve the sensitivity of short-term appetite control.
DOI: 10.18169/papdeott007074
title: Use and Validation of Known Powder Materials for Turbine Components for the Additive Manufacture of Corresponding Components
DOI: 10.18169/papdeott007083
title: Schlüsselverteilung bei industriellen Feldbussen mit Controller/Device Prinzip
DOI: 10.18169/papdeott007089
title: Steckbares Leistungsmodul
DOI: 10.18169/papdeott007098
title: Mobile Ladeinfrastruktur für Elektrofahrzeuge
DOI: 10.18169/papdeott007106
title: Automated Optimal Image Quality Defined by Voxel Size per Selected Coil
DOI: 10.18169/papdeott007122
title: Hochsicherheitszugang für Anlagentechnik zum Internet der Dinge (IoT)
DOI: 10.18169/papdeott007130
title: Protokollunterstützung bei beliebigen Spulenkombinatoriken
DOI: 10.5517/ccdc.csd.cc1q6rj6
title: CCDC 1585418: Experimental Crystal Structure Determination

description: Related Article: Malay Das,  and Anil K. Saikia|2018|J.Org.Chem.|83|6178|doi:10.1021/acs.joc.8b00440
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.18169/papdeott007131
title: Auswertesoftware zur Qualitätssicherung bei der Lagerung von MRT-Patienten
DOI: 10.18169/papdeott007132
title: Visualisierung der vorhergesagten Waggonbelegung in Bahnsystemen
DOI: 10.18169/papdeott007133
title: Reject Analysis mit Timer
DOI: 10.18169/papdeott007134
title: Verfahren zur kontinuierlichen Bildgebung peripherer Gelenke unter Belastung und Entlastung
DOI: 10.18169/papdeott007138
title: Verfahren zur patientengetriggerten Bildgebung peripherer Gelenke unter Belastung und Entlastung
DOI: 10.18169/papdeott007144
title: System and Method of Integrating Weather Forecast into Power System Planning and Energy Management Systems
DOI: 10.18169/papdeott007146
title: Self-Assembling Drones Used as Surface Coils for Magnet Resonance Imaging
DOI: 10.18169/papdeott007152
title: Tabletkamera als Navigationssystem für CT-Interventionen
DOI: 10.4225/08/5b164b6249582
title: Parkes observations for project P892 semester 2018APRS_BPSR_16

description: SUPERBx looks at the highest Galactic latitudes in a search for pulsars and fast radio bursts (FRBs). We use optimised GPU codes and supercomputing to search for these, making discoveries in real time. Handling our data as it comes in is essential for the SKA Phase I era so this work applies directly to the high-data rates of next generation telescopes. Our pulsar discoveries are typically nearby scintillating sources, intermittent sources and those in interesting binary systems. Our FRB discoveries have discovery lags of ~1 second, rather than months/years and these feed rapid alerts to the world-wide follow-up community via a dedicated VOEvent format an Astronomer's Telegrams. The goal of this is to allow localisation of the discovered FRBs. This is key for identifying FRB host galaxies, so as to solve the mystery of their progenitors and to exploit their many uses as tools for precision cosmology measurements.
DOI: 10.18169/papdeott007157
title: Fingerabdrucksensor bei Schaltern und Schaltanlagen der elektrischen Energieverteilung zur Sicherstellung der Schalthoheit
DOI: 10.18169/papdeott007158
title: Automated Surveillance of Intensive Care Unit Patients
DOI: 10.18169/papdeott007160
title: A Method and System for an Automatic Magnetic Resonance Study Parser using Deep Learning
DOI: 10.18169/papdeott007161
title: Methode zur Verbesserung der EMV-Abstrahlungen bei quasi-resonanten Schaltvorgängen
DOI: 10.18169/papdeott007163
title: Sicherstellung einer funkbasierten Kommunikationsverbindung basierend auf einer zeitlichen und räumlichen Anpassung der Abstrahlcharakteristik, der Abstrahlrichtung und der Feldstärke bei Funkantennen
DOI: 10.18169/papdeott007165
title: Schütz-Aufsatzmodul mit Motorschutzfunktion
DOI: 10.18169/papdeott007167
title: Parallelschaltung von Leistungsausgängen
DOI: 10.18169/papdeott007168
title: Integration von dosimetrischen Sensoren in Durchleuchtungsanlagen
DOI: 10.25810/4c3b-b819.2
title: World Newspaper Coverage of Climate Change or Global Warming, 2004-2018 - May 2018

description: The Media and Climate Change Observatory Data monitors 74 sources (across newspapers, radio and TV) in 38 countries in seven different regions around the world. Data is assembled by accessing archives through the Lexis Nexis, Proquest and Factiva databases via the University of Colorado libraries. More information may be found at: http://sciencepolicy.colorado.edu/icecaps/research/media_coverage/index.html. These data include Excel (.xlsx), CSV (.csv), and plain-text README files (.txt).
DOI: 10.4225/08/5b1766efd7f8e
title: Parkes observations for project P737 semester 2017OCTS_01

description: Pulsar observations using the Parkes radio telescope have led to some of the most exciting astronomical results in the last few years.  The aim of this proposal is to carry out tests of the new backend instruments which cannot be carried out during standard maintenance periods. High precision pulsar timing experiments require cross-coupling in the feed to be measured.  This can only be done using observations of PSR J0437-4715 from rise-to-set.  We propose to undertake such observations and make the results available for any users of the telescope.  We will also use P737 to commission new receivers such as the UWB.
DOI: 10.5517/ccdc.csd.cc1q94lr
title: CCDC 1587714: Experimental Crystal Structure Determination

description: Related Article: Tian-Xiang Lan, Xia Zhang, Chang-Neng Chen, Hui-Sheng Wang, Mei Wang, Yu-Hua Fan|2018|J.Coord.Chem.|71|1415|doi:10.1080/00958972.2018.1468563
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.14457/stou.the.2005.339
title: ความพึงพอใจต่อการเลี้ยงไหมพันธุ์ไทยพื้นเมือง ของเกษตรกรในจังหวัดกำแพงเพชร
DOI: 10.14457/stou.the.2005.340
title: แนวทางการส่งเสริมความยั่งยืน ของพืชพื้นบ้าน-อาหารพื้นเมือง : กรณีศึกษาภูมิปัญญาคนจันทบูร
DOI: 10.14457/stou.the.2005.341
title: การมีส่วนร่วมในการดำเนินงาน ด้านการแปรรูปกระท้อนของสมาชิกกลุ่มแม่บ้านเกษตรกร อำเภอเมือง จังหวัดปราจีนบุรี
DOI: 10.14457/stou.the.2005.342
title: ปัจจัยที่เกี่ยวข้องกับการยอมรับเทคโนโลยี การผลิตเมล็ดพันธุ์ข้าว ของเกษตรกรในจังหวัดสกลนคร
DOI: 10.14457/stou.the.2005.343
title: ปัจจัยที่เกี่ยวข้องกับการยอมรับ การผลิตข้าวหอมมะลิอินทรีย์ ของเกษตรกรทำนา เขตทุ่งกุลาร้องไห้ ในจังหวัดร้อยเอ็ด
DOI: 10.14457/stou.the.2005.344
title: การผลิตผักกระเฉด ของกลุ่มผู้ปลูกผักกระเฉด ในจังหวัดสมุทรปราการ