cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.28659185.v3
title: Methodology for generating chorioallantoic membrane patient-derived xenograft (CAM-PDX) models of pleural mesothelioma and performing preclinical imaging for the translation of cancer studies and drug screening

description: <b>Background</b>Pleural mesothelioma is a cancer of the lung lining associated with asbestos exposure. Platinum/pemetrexed chemotherapy has been used for many years but provides little benefit and, despite recent immunotherapy advances, prognosis remains poor underpinning the need for development of novel therapeutics or drug repurposing. Fertilized hens’ eggs provide a rapid and cost-effective alternative to murine models of pleural mesothelioma which are commonly used in preclinical studies, with chorioallantoic membrane (CAM) xenografts being a partial replacement for mouse flank xenografts. Here we describe methods to generate mesothelioma patient-derived xenografts on the CAM (CAM-PDX), and to subsequently assess these PDX nodules by preclinical imaging and histology.<b>Methods</b>Fragments of surplus mesothelioma tissue obtained from patient biopsies were implanted onto the CAM on embryonic day 7 (E7), fresh or following cryopreservation, with the established PDX dissected on E14 and fixed for histological/immunohistochemical analysis. The optimal freezing method was determined by comparing tissue integrity and cellular content of cryopreserved tissue fragments with paired fresh samples via histological/immunohistochemical analyses. [<sup>18</sup>F]-fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) was used to assess viability of PDXs <i>in ovo.</i><b>Results</b>Methodologies for processing, cryopreservation, re-animation, and engraftment of mesothelioma tissue fragments were established. Cryopreservation of biopsy samples and parallel processing of contiguous sections allows for assessment of mesothelioma cellularity. CAM-PDXs, generated from fresh or slow-frozen tissue, were well vascularized whilst maintaining the architecture and cellular composition of the patient tissue. Furthermore, uptake of [<sup>18</sup>F]-FDG following intravenous injection could be visualized and quantified.<b>Conclusions</b>The CAM is a rapid platform for engrafting patient-derived tissue, maintaining elements of the tumor microenvironment and recapitulating heterogeneity observed in mesothelioma. Combining the CAM-PDX model and FDG-PET/CT provides a quantitative<i> in vivo </i>platform for pre-screening of novel treatment strategies and drug combinations, with the potential for development of patient tumor avatars for predicting clinical response.
DOI: 10.5281/zenodo.15734293
title: All-sky Radiative Fluxes Computed by GRTcode using ERA5 Reanalysis and CMIP7 Input4MIPs as Inputs for 2001 to 2024

description: All-sky Radiative Fluxes Computed by GRTcode using ERA5 Reanalysis and CMIP7 Input4MIPs as Inputs for 2001 to 2024. These results are spectrally integrated as longwave broadband fluxes for assessible data size. Spectrally resolved results are avaiable upon request to Jing.Feng@princeton.edu.

GRTcode is available at https://github.com/fengzydy/GRTCODE.git

Using annual-mean, monthly-mean surface temperature, humidity, ozone concentration, and cloud conditions from the ERA5 reanalysis dataset (Hersbach et al., 2020), a set of global-scale line-by-line experiments perturbing the concentrations of well-mixed greenhouse gases was conducted for the period 2001–2024. These experiments include:



Control: A control experiment using a time series of global-mean, annual-mean concentrations of WMGHGs (Nicolls et al., 2025, as included in control.nc).

xPI: Identical to Control, except that an individual WMGHG species, x, is held fixed at its 1850 concentration (as included in PI.nc).

CO24xPI: Similar to CO2PI, except that CO2  concentration is four times of 1850 concentration.
DOI: 10.15468/dl.q8wphd
title: Occurrence Download

description: A dataset containing 15 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Ecuador",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Stenocercus festae",
 "Year 2020-2025"
 ]
}

 The dataset includes 15 records from 5 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0029544-250802193616735/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.25574/07587
title: Chandra X-ray Observatory ObsId 07587

description: HETG Spectroscopy of the Crab Pulsar and the Interstellar Medium
DOI: 10.15468/dl.n7zrcn
title: Occurrence Download

description: A dataset containing 59427 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 "BasisOfRecord is one of (Human Observation, Machine Observation, Occurrence evidence, Observation)",
 "TaxonKey is one of (Synallaxis spixi)",
 "Country is one of (Anguilla, Antigua and Barbuda, Argentina, Aruba, Bahamas, Barbados, Belize, Bolivia (Plurinational State of), Bonaire, Sint Eustatius and Saba, Bouvet Island, Brazil, Cayman Islands, Chile, Colombia, Costa Rica, Cuba, Curaçao, Dominica, Dominican Republic, Ecuador, El Salvador, Falkland Islands (Malvinas), French Guiana, Grenada, Guadeloupe, Guatemala, Guyana, Haiti, Honduras, Jamaica, Martinique, Mexico, Montserrat, Nicaragua, Panama, Paraguay, Peru, Puerto Rico, Saint Barthélemy, Saint Kitts and Nevis, Saint Lucia, Saint Martin (French part), Saint Vincent and the Grenadines, Sint Maarten (Dutch part), South Georgia and the South Sandwich Islands, Suriname, Trinidad and Tobago, Turks and Caicos Islands, Uruguay, Venezuela (Bolivarian Republic of), Virgin Islands (British), Virgin Islands (U.S.))"
 ]
}

 The dataset includes 59427 records from 24 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0029518-250802193616735/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.29868284
title: How to assess breast cancer risk in menopausal patients being treated with menopausal hormone therapy?

description: The administration of Menopausal Hormone Therapy (MHT) needs to be evaluated in relation to the individual patient’s indications for therapy and risk estimations, which include the Breast Cancer (BC) risk estimation. We reviewed the lifetime BC risk and the associated mortality in relation to MHT use. For many patients with climacteric symptoms and/or osteoporosis, the balance is in favor of MHT use. The risk of breast cancer can be estimated using unmodifiable risk factors, such as the patient’s personal and family history, the breast density assessed on her mammogram, and modifiable risk factors such as alcohol intake. In complex situations, prediction models can be used to guide decision-making. When the 5-year BC risk is low (below 3%), MHT can be prescribed; caution is needed in women with a risk between 3% and 6%, and MHT should generally be avoided when the risk is high, i.e. above 6%.
DOI: 10.6084/m9.figshare.29868284.v1
title: How to assess breast cancer risk in menopausal patients being treated with menopausal hormone therapy?

description: The administration of Menopausal Hormone Therapy (MHT) needs to be evaluated in relation to the individual patient’s indications for therapy and risk estimations, which include the Breast Cancer (BC) risk estimation. We reviewed the lifetime BC risk and the associated mortality in relation to MHT use. For many patients with climacteric symptoms and/or osteoporosis, the balance is in favor of MHT use. The risk of breast cancer can be estimated using unmodifiable risk factors, such as the patient’s personal and family history, the breast density assessed on her mammogram, and modifiable risk factors such as alcohol intake. In complex situations, prediction models can be used to guide decision-making. When the 5-year BC risk is low (below 3%), MHT can be prescribed; caution is needed in women with a risk between 3% and 6%, and MHT should generally be avoided when the risk is high, i.e. above 6%.
DOI: 10.15468/dl.c5y677
title: Occurrence Download

description: A dataset containing 26259 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Streptopelia vinacea)",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 "License is one of (CC-BY 4.0, CC0 1.0)"
 ]
}

 The dataset includes 26259 records from 60 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0029545-250802193616735/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.hdwkce
title: Occurrence Download

description: A dataset containing 559 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Streptopelia xanthocycla)",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 "License is one of (CC-BY 4.0, CC0 1.0)"
 ]
}

 The dataset includes 559 records from 3 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0029546-250802193616735/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.jy6377
title: Occurrence Download

description: A dataset containing 26 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is BOLD:AAB3777"
 ]
}

 The dataset includes 26 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0029547-250802193616735/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.g5bnsu
title: Occurrence Download

description: A dataset containing 311 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Viet Nam",
 "TaxonKey is Angiopteris"
 ]
}

 The dataset includes 311 records from 26 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0029548-250802193616735/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.16781095
title: Global evapotranspiration datasets used in "Evaluation of global evapotranspiration products over irrigated areas using multiple reference datasets", resampled to 0.1° and aggregated monthly

description: Dataset description

This dataset contains the global evapotranspiration (ET) products and reference datasets used in Laluet et al. (2025), Evaluation of global evapotranspiration products over irrigated areas using multiple reference datasets, Hydrology and Earth System Sciences.

Contents

The datasets include:





Six global ET products:





FLUXCOM (RS) – 2001–2020




GLEAMv4 (v4.2a) – 2000–2024




MOD16A2 (v105) – 2001–2023




ERA5-Land (2024 CDS release) – 2000–2024




SSEBop (v6.1) – 2012–2024




PMLv2 (v0.1.8) – 2000–2023






FAO Global Map of Irrigation Areas (GMIA)




OpenET ensemble product (for CONUS only)



Study regions





Contiguous United States (CONUS)




Ebro Basin (Spain)




Italy (including the Po Valley)




South Asia (including the Indus Basin)



Processing applied





All datasets have been resampled to a 0.1° spatial resolution




Aggregated to monthly time steps



Coverage





FLUXCOM: 2001–2020




GLEAMv4: 2000–2024




MOD16A2: 2001–2023




ERA5-Land: 2000–2024




SSEBop: 2012–2024




PMLv2: 2000–2023


OpenET ensemble product: 2016–2022


Format





NetCDF4 (CF-compliant metadata)



Licence





Creative Commons Attribution 4.0 International (CC-BY 4.0)



Reference paper

Laluet, P., Dorigo, W., & Corbari, C. (2025). Evaluation of global evapotranspiration products over irrigated areas using multiple reference datasets. Hydrology and Earth System Sciences. [DOI of the paper]

Funding

This work was carried out with support from the European Space Agency under the Climate Change Initiative – Anthropogenic Water Use (CCI-AWU) precursor project (contract number 4000142449/23/I-NB).

Contact

pierre.laluet@geo.tuwien.ac.at
DOI: 10.15468/dl.5ckwgb
title: Occurrence Download

description: A dataset containing 2073 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Cenostigma bracteosum"
 ]
}

 The dataset includes 2073 records from 110 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0029549-250802193616735/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.92q2m7
title: Occurrence Download

description: A dataset containing 11353815 species occurrences available in GBIF matching the query:
(Query is too complex. Can be viewed on the landing page)

 The dataset includes 11353815 records from 6901 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0029512-250802193616735/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.3535/0k7-g7g-7fz
title: †Rotularia bognoriensis (Mantell, 1822)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/9l0-l1r-h2m
title: Animalia

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/jk0-1sx-v71
title: Animalia

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/ma7-4s0-ce3
title: †Peltoceras athleta (Phillips, 1829)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/a4l-f09-6ms
title: Pseudothurmannia

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/akr-ggy-epn
title: Animalia

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/j2r-4qk-98v
title: Cnidaria

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/959-k2q-2tn
title: Mammalia Linnaeus, 1758

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/df5-31b-s07
title: Chondrichthyes

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/mpm-n58-bse
title: Equus (Equus) caballus Linnaeus, 1758

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/v8a-vll-jlw
title: Mammalia Linnaeus, 1758

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/m5n-29j-s2z
title: Animalia

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/tw1-0lr-ttd
title: Mammalia Linnaeus, 1758

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/yqs-25h-xw7
title: Mammalia Linnaeus, 1758

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/td7-xpy-n1s
title: Bos taurus Linnaeus, 1758

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/zwh-vxx-151
title: Crioceratites

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.15468/dl.2q6r25
title: Occurrence Download

description: A dataset containing 138 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Acanthochromis polyacanthus",
 "Country is United States of America",
 "HasCoordinate is true"
 ]
}

 The dataset includes 138 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0022310-250811113504898/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.3535/kwa-93l-nss
title: Bos taurus Linnaeus, 1758

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/9ys-2pk-f36
title: Aves

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/xjr-pa5-mv9
title: Amblyraja radiata (Donovan, 1808)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/b21-jxk-4y0
title: Brachiopoda Duméril, 1805

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/h18-snn-mhf
title: Animalia

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/94d-608-c5g
title: Animalia

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/v1a-hwn-ntg
title: Phacops

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/pzw-039-wyn
title: Mammalia Linnaeus, 1758

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.5281/zenodo.16901353
title: Determinants of crime in the United States
DOI: 10.3535/l5z-457-nv6
title: Animalia

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/sl1-cn8-egw
title: Muscardinus Kaup, 1829

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.5281/zenodo.16901352
title: Determinants of crime in the United States
DOI: 10.3535/5q6-wpp-6zy
title: Mammalia Linnaeus, 1758

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/btd-h5e-6tq
title: Mammalia Linnaeus, 1758

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/fkg-m0g-x3e
title: Mammalia Linnaeus, 1758

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/x2c-bpj-89d
title: Mammalia Linnaeus, 1758

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/eje-vfe-nml
title: Mammalia Linnaeus, 1758

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/q0e-l1e-lka
title: Ovis aries Linnaeus, 1758

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/y77-xfx-h6f
title: Mammalia Linnaeus, 1758

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/7t8-4n6-vm7
title: Mammalia Linnaeus, 1758

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/gze-4es-lxw
title: †Pseudolimea Arkell, 1933

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/er4-ty5-yf6
title: †Applinocrinus cretaceus Peck, 1973

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/lw3-ck3-9sb
title: Plant remains

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/7st-e9w-j34
title: Pseudothurmannia

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/bnp-2rw-2tv
title: Animalia

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/1cm-59h-f3q
title: Animalia

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/zgb-5t2-zyd
title: Mammalia Linnaeus, 1758

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/wy6-pvk-83w
title: Bos taurus Linnaeus, 1758

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.5066/p9yqchsr
title: Data Associated with Poecivirus Testing of Individual Birds with Beak Deformities

description: This data set is comprised of two tables, one with results of poecivirus screening of tissues from six North American avian species using PCR followed by Sanger sequencing in addition to unbiased metagenomic sequencing, the second lists the names and sequences of primers used.
DOI: 10.5281/zenodo.15265399
title: Retrospective performance-indexed analysis of Thoroughbred racehorses undergoing surgical management of proximal sesamoid bone fractures
DOI: 10.5281/zenodo.15265400
title: Retrospective performance-indexed analysis of Thoroughbred racehorses undergoing surgical management of proximal sesamoid bone fractures
DOI: 10.6084/m9.figshare.28830278.v9
title: Reconstructed Zurich Air Pollution Data (2015–2019) with Lag Structure for Urinary Metal Toxicokinetic Analysis

description: This dataset contains reconstructed daily air pollution data from the Zurich NABEL monitoring station (“Kaserne”) between 2015 and 2019, including NO₂, SO₂, CO, PM₁₀, PM₂.₅, and derived PM₁₀–₂.₅ values. A few missing values for all pollutants except PM₂.₅ were imputed using linear interpolation, while missing PM₂.₅ values were reconstructed using an XGBoost-based machine learning model trained on the remaining pollutants. All imputed values are flagged accordingly.To enable toxicokinetic modeling of airborne metal exposure, the dataset includes:14-day average concentrations for each pollutant preceding the urine test,27 lagged weekly averages (lag –1 to –26) aligned with the dates of Chelate-Evoked Metal Excretion Testing (CEMET) conducted at a clinical center in Pfäffikon SZ, Switzerland.The lag structure was designed to explore the delay between environmental exposure and urinary excretion of heavy metals. These lag times are still largely unknown, which may explain why many environmental impact studies fail to detect associations between pollutant exposure and metal biomarkers. This dataset provides a novel foundation for investigating these temporal dynamics.
DOI: 10.5066/p9b5bskq
title: Serological Survey Data for Francisella tularensis and Brucella spp. Exposure in Wildlife on the Arctic Coastal Plain of Alaska

description: This dataset consists of one table with diagnostic screening results from a study of Francisella tularensis bacteria exposure in tundra-nesting geese and mammals and Brucella spp. exposure in mammals sampled from multiple locations on the Arctic Coastal Plain of Alaska, 2014-2017. The table provides sample collection and location data of geese, arctic fox, red fox, caribou, small mammal, and polar bear samples.
DOI: 10.5067/hhk2qt3lqmel
title: Antarctic_Mosaics
DOI: 10.5067/r0aricrbakye
title: UAVSAR_RPI
DOI: 10.5067/7peqv8svr4dm
title: UAVSAR_POLSAR
DOI: 10.5067/f1sc87efgt9u
title: AirSAR_TOPSAR
DOI: 10.5067/snwg/opera_l2_cslc-s1-static_calval_v1
title: OPERA Coregistered Single-Look Complex from Sentinel-1 Static Layers product for Calibration &amp; Validation (Version 1)