cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q2th8n6t
title: BindingDB Entry 50034739: -cyano-substituted analogoues of decarboxylated S-adenosylmethionine as enzyme activated, irreversible inhibitors of S-adenosylmethionine decarboxylase

description: Small molecule binding data for protein S-adenosylmethionine decarboxylase 1, Uniprot P17707
DOI: 10.7270/q2w66mh6
title: BindingDB Entry 50037403: 3-Thio-1,2,4-triazoles, novel somatostatin sst2/sst5 agonists.

description: Small molecule binding data for protein Somatostatin receptor, Uniprot P30872, P30874, P31391, P32745, and P35346
DOI: 10.7270/q2wh2qnt
title: BindingDB Entry 50036496: N6,C8-distributed adenosine derivatives as partial agonists for adenosine A1 receptors.

description: Small molecule binding data for protein Adenosine receptor A1, Uniprot P25099
DOI: 10.7270/q2wm1dzs
title: BindingDB Entry 50035569: Potential inhibitors of S-adenosylmethionine-dependent methyltransferases. 10. Base- and amino acid modified analogues of S-aristeromycinyl-L-homocysteine.

description: Small molecule binding data for protein Histamine N-methyltransferase and Phenylethanolamine N-methyltransferase, Uniprot P10938 and P50135
DOI: 10.7270/q2xk8g31
title: BindingDB Entry 50035560: N-[2-hydroxy-5-[2-(methylamino)ethyl]phenyl]methanesulfonamide. A potent agonist which releases intracellular calcium by activation of alpha 1-adrenoceptors.

description: Small molecule binding data for protein Alpha-1A adrenergic receptor, Uniprot P35348
DOI: 10.7270/q2xp75b3
title: BindingDB Entry 50033855: Synthesis of rhodamine B-benzenesulfonamide conjugates and their inhibitory activity against humana- and bacterial/fungalß-carbonic anhydrases.

description: Small molecule binding data for protein Carbonic Anhydrase III, Carbonic Anhydrase VA, Carbonic Anhydrase VB, Carbonic Anhydrase XIV, Carbonic anhydrase, Carbonic anhydrase 12, Carbonic anhydrase 13 (CA XIII), Carbonic anhydrase 2, Carbonic anhydrase 4, Carbonic anhydrase 6 (CA-VI), Carbonic anhydrase 7, Carbonic anhydrase 9, and beta-Carbonic Anhydrase, Uniprot O43570, P00915, P00918, P07451, P22748, P23280, P35218, P43166, Q16790, Q5AJ71, Q8N1Q1, Q9ULX7, and Q9Y2D0
DOI: 10.7270/q2z89cwp
title: BindingDB Entry 50034738: Synthesis and excitatory amino acid pharmacology of some novel quinoxalinediones

description: Small molecule binding data for protein Glutamate-NMDA, Uniprot P35439
DOI: 10.7270/q20002t6
title: BindingDB Entry 50037410: Synthesis of an N-acyl sulfamate analog of luciferyl-AMP: a stable and potent inhibitor of firefly luciferase.

description: Small molecule binding data for protein Luciferase, Uniprot Q01158
DOI: 10.7270/q20865z8
title: BindingDB Entry 50036504: Opioid antagonist activity of naltrexone-derived bivalent ligands: importance of a properly oriented molecular scaffold to guide"address" recognition at kappa opioid receptors.

description: Small molecule binding data for protein Delta-type opioid receptor and mu/kappa opioid receptor, Uniprot P41143, P41144, and P97266
DOI: 10.7270/q20c4wb5
title: BindingDB Entry 50035580: New bidentates as full inhibitors of enkephalin-degrading enzymes: synthesis and analgesic properties.

description: Small molecule binding data for protein Aminopeptidase N and Neutral Endopeptidase (NEP), Uniprot P07861 and P15145
DOI: 10.7270/q21g0mnq
title: BindingDB Entry 50033863: Design and synthesis of novel amide AKT1 inhibitors with selectivity over CDK2.

description: Small molecule binding data for protein AKT/p21CIP1 and Cyclin-dependent kinase 2, Uniprot P24941 and P31749
DOI: 10.7270/q2319wj7
title: BindingDB Entry 50036512: Binding affinities for sulfonamide inhibitors with human thrombin using Monte Carlo simulations with a linear response method.

description: Small molecule binding data for protein Prothrombin, Uniprot P00734
DOI: 10.7270/q23r0tm4
title: BindingDB Entry 50037409: Lead optimization of 4-(dimethylamino)quinazolines, potent and selective antagonists for the melanin-concentrating hormone receptor 1.

description: Small molecule binding data for protein Alpha-2A adrenergic receptor, Melanin-concentrating hormone receptor, and Neuropeptide Y receptor type 5 ( NPY Y5), Uniprot P08913, Q15761, and Q99705
DOI: 10.7270/q2416xq2
title: BindingDB Entry 50036503: Synthesis and biological activity of novel nonsteroidal progesterone receptor antagonists based on cyclocymopol monomethyl ether.

description: Small molecule binding data for protein Androgen Receptor, Glucocorticoid receptor, Mineralocorticoid receptor (MR), and Progesterone receptor, Uniprot P04150, P06401, P08235, and P10275
DOI: 10.7270/q2445n2w
title: BindingDB Entry 50035578: Synthesis of xanthines as adenosine antagonists, a practical quantitative structure-activity relationship application.

description: Small molecule binding data for protein Adenosine A1 receptor and Adenosine receptor A1, Uniprot P25099 and P28190
DOI: 10.7270/q2474b72
title: BindingDB Entry 50033870: Anti-inflammatory endiandric acid analogues from the roots of Beilschmiedia tsangii.

description: Small molecule binding data for protein Nitric Oxide Synthase, inducible, Uniprot P29477
DOI: 10.7270/q24t6jv7
title: BindingDB Entry 50034752: The syntheses and binding affinities of tools for the study of angiotensin AT2 receptors

description: Small molecule binding data for protein Angiotensin II receptor, Uniprot P50052
DOI: 10.7270/q2571cdw
title: BindingDB Entry 50033862: Characteristic of alkylated chalcones from Angelica keiskei on influenza virus neuraminidase inhibition.

description: Small molecule binding data for protein Neuraminidase, Uniprot Q9IGQ6
DOI: 10.7270/q26h4j51
title: BindingDB Entry 50037417: Structure-activity relationship studies on ortho-substituted cinnamic acids, a new class of selective EP(3) antagonists.

description: Small molecule binding data for protein Prostaglandin E2 receptor, Prostaglandin E2 receptor EP1 subtype (EP1), Prostaglandin E2 receptor EP2 subtype (EP2), and Prostaglandin E2 receptor EP4 subtype (EP4), Uniprot P34995, P35408, P43115, and P43116
DOI: 10.7270/q26t0n9n
title: BindingDB Entry 50036511: Smart region definition: a new way to improve the predictive ability and interpretability of three-dimensional quantitative structure-activity relationships.

description: Small molecule binding data for protein Brain glycogen phosphorylase, Uniprot P11216
DOI: 10.7270/q27w6csw
title: BindingDB Entry 50035577: 10-Ketonaltrexone and 10-ketooxymorphone.

description: Small molecule binding data for protein Delta-type opioid receptor and mu/kappa opioid receptor, Uniprot P41143, P41144, and P97266
DOI: 10.7270/q28g8m63
title: BindingDB Entry 50034751: The rational design and synthesis of non-peptide rhegnylogues of CCK-26-33 - a novel series of CCK-A selective ligands

description: Small molecule binding data for protein Cholecystokinin receptor, Uniprot P30551 and P56481
DOI: 10.7270/q2bk1d1c
title: BindingDB Entry 50036510: Synthesis and structure-activity relationships of 17beta-substituted 14beta-hydroxysteroid 3-(alpha-L-rhamnopyranoside)s: steroids that bind to the digitalis receptor.

description: Small molecule binding data for protein Sodium/potassium-transporting ATPase alpha-1 chain, Uniprot P50997
DOI: 10.7270/q2cj8f4r
title: BindingDB Entry 50036500: Use of a dipeptide chemical library in the development of non-peptide tachykinin NK3 receptor selective antagonists.

description: Small molecule binding data for protein Neurokinin 1 receptor, Neurokinin 3 receptor, TACR2, and TACR3, Uniprot P16177, P25103, P29371, P30098, and P51144
DOI: 10.7270/q2cn74hm
title: BindingDB Entry 50035575: Synthesis of the antileukemic agents 5,10-dideazaaminopterin and 5,10-dideaza-5,6,7,8-tetrahydroaminopterin.

description: Small molecule binding data for protein Dihydrofolate reductase, Dihydrofolate reductase (DHFR), and Thymidylate Synthase (TS), Uniprot P00376, P00381, and P00469
DOI: 10.7270/q2cr5tr9
title: BindingDB Entry 50033868: Cracking the molecular weight barrier: fragment screening of an aminotransferase using an NMR-based functional assay.

description: Small molecule binding data for protein Branched-chain-amino-acid transferase, Uniprot P54687
DOI: 10.7270/q2d79bwz
title: BindingDB Entry 50034750: Synthesis of a potent and selective non-peptide CCK-B/gastrin receptor antagonist tritiated ligand.

description: Small molecule binding data for protein Cholecystokinin receptor, Uniprot P30551, P32239, and P56481
DOI: 10.7270/q2g161m2
title: BindingDB Entry 50037415: (2S,1'S,2'R,3'R)-2(2'-Carboxy-3'-hydroxymethylcyclopropyl)glycine-[3H], a potent and selective radioligand for labeling group 2 and 3 metabotropic glutamate receptors.

description: Small molecule binding data for protein GRM8, Uniprot O00222
DOI: 10.7270/q2gb24q7
title: BindingDB Entry 50036509: Conformationally constrained [p-(omega-aminoalkyl)phenacetyl]-L-seryl-L-lysyl dipeptide amides as potent peptidomimetic inhibitors of Candida albicans and human myristoyl-CoA:protein N-myristoyl transferase.

description: Small molecule binding data for protein Myristoyl-CoA:protein N-myristoyltransferase (Nmt), Uniprot P30418
DOI: 10.7270/q2gf0v34
title: BindingDB Entry 50035585: Synthesis and biological activity of modified peptide inhibitors of angiotensin-converting enzyme.

description: Small molecule binding data for protein Angiotensin-converting enzyme, Uniprot P12821
DOI: 10.7270/q2h132sw
title: BindingDB Entry 50037406: Carbonic anhydrase inhibitors: design of thioureido sulfonamides with potent isozyme II and XII inhibitory properties and intraocular pressure lowering activity in a rabbit model of glaucoma.

description: Small molecule binding data for protein Carbonic anhydrase, Carbonic anhydrase 12, and Carbonic anhydrase 2, Uniprot O43570, P00915, and P00918
DOI: 10.7270/q2hh6kfk
title: BindingDB Entry 50033867: Structure-based optimization of potent 4- and 6-azaindole-3-carboxamides as renin inhibitors.

description: Small molecule binding data for protein Renin, Uniprot P00797
DOI: 10.7270/q2j103m7
title: BindingDB Entry 50034749: Biological properties of (R)-4-benzamido-5-oxopentanoic basic derivatives as CCK-antagonists

description: Small molecule binding data for protein Cholecystokinin receptor, Uniprot P30551 and P32239
DOI: 10.7270/q2ks6sb3
title: BindingDB Entry 50037413: Synthesis and biological activity of 3,4-dihydroquinazolines for selective T-type Ca2+ channel blockers.

description: Small molecule binding data for protein Voltage-gated T-type calcium channel, Uniprot O43497
DOI: 10.7270/q2m0463j
title: BindingDB Entry 50036508: Synthesis and in vitro activity of 3 beta-substituted-3 alpha-hydroxypregnan-20-ones: allosteric modulators of the GABAA receptor.

description: Small molecule binding data for protein GABA receptor alpha-1/beta-2/gamma-2 subunit, Uniprot P14867, P18507, and P47870
DOI: 10.7270/q2n58mrk
title: BindingDB Entry 50033866: Discovery of amide replacements that improve activity and metabolic stability of a bis-amide smoothened antagonist hit.

description: Small molecule binding data for protein G-protein- coupled-like receptor Smoothened (Smo) and Smoothened homolog, Uniprot P56726 and Q99835
DOI: 10.7270/q2n58mxt
title: BindingDB Entry 50035571: A new generation of phosphodiesterase inhibitors: multiple molecular forms of phosphodiesterase and the potential for drug selectivity.

description: Small molecule binding data for protein cGMP-dependent 3',5'-cyclic phosphodiesterase, Uniprot O00408
DOI: 10.7270/q2ns0vcq
title: BindingDB Entry 50034748: Peptidomimetic inhibitors of human immunodeficiency virus protease (HIV-PR): Design, enzyme binding and selectivity, antiviral efficacy, and cell permeability properties

description: Small molecule binding data for protein Cathepsin D, Cathepsin E, Human immunodeficiency virus type 1 protease, Human rhinovirus A protease, Pepsin A, and Renin, Uniprot P00791, P00797, P07339, and P14091
DOI: 10.7270/q2qj7j2t
title: BindingDB Entry 50037412: Discovery of a novel, potent and selective human beta3-adrenergic receptor agonist.

description: Small molecule binding data for protein Beta-1 adrenergic receptor, Beta-2 adrenergic receptor and beta-3 adrenergic receptor, and Beta-3 adrenergic receptor, Uniprot P07550, P08588, and P13945
DOI: 10.7270/q2qr4xr8
title: BindingDB Entry 50036507: Rationally designed inhibitors of inosine monophosphate dehydrogenase.

description: Small molecule binding data for protein Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2), Uniprot P12268
DOI: 10.7270/q2qz2bhd
title: BindingDB Entry 50035583: Potential neuroleptic agents. 3. Chemistry and antidopaminergic properties of substituted 6-methoxysalicylamides.

description: Small molecule binding data for protein Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor, Uniprot P61169
DOI: 10.7270/q2rv0p8x
title: BindingDB Entry 50035570: 1,3-Dialkyl-8-(p-sulfophenyl)xanthines: potent water-soluble antagonists for A1- and A2-adenosine receptors.

description: Small molecule binding data for protein Adenosine A2a receptor and Adenosine receptor A1, Uniprot P25099 and P46616
DOI: 10.7270/q2rx9cfj
title: BindingDB Entry 50033865: Structure-based design and optimization of potent renin inhibitors on 5- or 7-azaindole-scaffolds.

description: Small molecule binding data for protein Renin, Uniprot P00797
DOI: 10.7270/q2sj1m3f
title: BindingDB Entry 50034747: Antiinflammatory -benzeneethanamines. III

description: Small molecule binding data for protein Arachidonate 5-lipoxygenase, Group VII phospholipase A2, Phospholipase A2 group 1B, Prostaglandin D2 synthase, and Prostaglandin G/H synthase (cyclooxygenase), Uniprot O02853, P04055, P05979, P12527, and P79208
DOI: 10.7270/q2v69kbc
title: BindingDB Entry 50037411: L-arginine analogs as alternate substrates for nitric oxide synthase.

description: Small molecule binding data for protein Nitric oxide synthase, inducible, Uniprot P35228
DOI: 10.7270/q2vh5pg0
title: BindingDB Entry 50036506: Stereoselective synthesis and biodistribution of potent [11C]-labeled antagonists for positron emission tomography imaging of muscarinic receptors in the airways.

description: Small molecule binding data for protein Muscarinic acetylcholine receptor M1, Muscarinic acetylcholine receptor M3, and Muscarinic receptor M2 and M3, Uniprot P08482 and P10980
DOI: 10.7270/q2vm4cvv
title: BindingDB Entry 50035582: Synthesis and biological evaluation of phosphonamidate peptide inhibitors of enkephalinase and angiotensin-converting enzyme.

description: Small molecule binding data for protein Angiotensin-converting enzyme-related carboxypeptidase and Neutral Endopeptidase (NEP), Uniprot P07861 and Q5EGZ1
DOI: 10.7270/q2wq045t
title: BindingDB Entry 50033864: New pyrazolyl and thienyl aminohydantoins as potent BACE1 inhibitors: exploring the S2' region.

description: Small molecule binding data for protein Beta-secretase 1, Beta-secretase 2 (BACE2), and Cathepsin D, Uniprot P07339, P56817, and Q9Y5Z0
DOI: 10.7270/q2x92bs9
title: BindingDB Entry 50034746: ()-7-deazaaristeromycin lacking the hydroxymethyl substituent

description: Small molecule binding data for protein Adenosylhomocysteinase, Uniprot P23526
DOI: 10.7270/q20g3khb
title: BindingDB Entry 50033871: Inhibitors of androgen receptor activation function-2 (AF2) site identified through virtual screening.

description: Small molecule binding data for protein Androgen Receptor, Uniprot P10275
DOI: 10.7270/q2125t5p
title: BindingDB Entry 50034753: The conserved acid binding domain model of inhibitors of protein phosphatases 1 and 2A: Molecular modelling aspects.

description: Small molecule binding data for protein Protein-tyrosine phosphatase 1B and Serine/threonine protein phosphatase 2A, 56 kDa regulatory subunit, alpha isoform, Uniprot P18031 and Q15172
DOI: 10.7270/q21r6r9x
title: BindingDB Entry 50037428: Bis(aminopyrrolidine)-derived ureas (APUs) as potent MCH1 receptor antagonists.

description: Small molecule binding data for protein Melanin-concentrating hormone receptor, Uniprot Q99705
DOI: 10.7270/q2222vdd
title: BindingDB Entry 50036520: Non-peptide glycoprotein IIb/IIIa inhibitors. 17. Design and synthesis of orally active, long-acting non-peptide fibrinogen receptor antagonists.

description: Small molecule binding data for protein Fibronectin receptor beta/Integrin alpha5, Integrin alpha-IIb/beta-3, and Integrin beta-3/Vitronectin receptor alpha, Uniprot P05106, P05556, P06756, P08514, and P08648
DOI: 10.7270/q22r3sdv
title: BindingDB Entry 50037418: Carbonic anhydrase inhibitors. Inhibition of isozymes I, II, IV, V, and IX with anions isosteric and isoelectronic with sulfate, nitrate, and carbonate.

description: Small molecule binding data for protein Carbonic Anhydrase VA, Carbonic anhydrase, Carbonic anhydrase 2, Carbonic anhydrase 4, and Carbonic anhydrase 9, Uniprot P00915, P00918, P22748, P35218, and Q16790
DOI: 10.7270/q2348kx3
title: BindingDB Entry 50035590: Inactivation of gamma-aminobutyric acid aminotransferase by (S,E)-4-amino-5-fluoropent-2-enoic acid and effect on the enzyme of (E)-3-(1-aminocyclopropyl)-2-propenoic acid.

description: Small molecule binding data for protein Gamma-amino-N-butyrate transaminase, Uniprot P80147
DOI: 10.7270/q25h7h1n
title: BindingDB Entry 50037427: Carbonic anhydrase inhibitors. Inhibition of the human cytosolic isozyme VII with aromatic and heterocyclic sulfonamides.

description: Small molecule binding data for protein Carbonic Anhydrase III, Carbonic Anhydrase XIII, Carbonic anhydrase, Carbonic anhydrase 2, Carbonic anhydrase 7, and Carbonic anhydrase VII, Uniprot P00915, P00918, P07451, P43166, Q9D6N1, and Q9ERQ8
DOI: 10.7270/q25t3m4t
title: BindingDB Entry 50036519: 9-Benzyladenines: potent and selective cAMP phosphodiesterase inhibitors.

description: Small molecule binding data for protein Adenosine receptor A1, cGMP-dependent 3',5'-cyclic phosphodiesterase, and cGMP-specific 3',5'-cyclic phosphodiesterase, Uniprot O00408, O76074, and P30542
DOI: 10.7270/q26w9bnh
title: BindingDB Entry 50035587: Replacement of the ribofuranose oxygen of 2-5A derivatives by methylene: synthesis of an aristeromycin analogue of 2-5A core 5'-monophosphate (5'-O-phosphoryladenylyl)(2'----5')adenyl(2'----5')adenosine.

description: Small molecule binding data for protein RNase L, Uniprot Q05823 and Q05921
DOI: 10.7270/q27081t0
title: BindingDB Entry 50033878: Synthesis and Na+/H+ exchanger inhibitory activity of benzoylguanidine derivatives.

description: Small molecule binding data for protein Sodium/hydrogen exchanger 1, Uniprot P26431
DOI: 10.7270/q2805307
title: BindingDB Entry 50033869: A novel amino-benzosuberone derivative is a picomolar inhibitor of mammalian aminopeptidase N/CD13.

description: Small molecule binding data for protein Aminopeptidase N, Bacterial leucyl aminopeptidase, and Cytosol aminopeptidase, Uniprot P00727, P15145, and Q01693
DOI: 10.7270/q29887rz
title: BindingDB Entry 50037426: Carbonic anhydrase inhibitors. Inhibition of the transmembrane isozyme XII with sulfonamides-a new target for the design of antitumor and antiglaucoma drugs?

description: Small molecule binding data for protein Carbonic anhydrase, Carbonic anhydrase 12, and Carbonic anhydrase 2, Uniprot O43570, P00915, and P00918
DOI: 10.7270/q29k4bwk
title: BindingDB Entry 50036518: Biological and conformational examination of stereochemical modifications using the template melanotropin peptide, Ac-Nle-c[Asp-His-Phe-Arg-Trp-Ala-Lys]-NH2, on human melanocortin receptors.

description: Small molecule binding data for protein Melanocortin receptor 3 (MC3R), Melanocortin receptor 4, Melanocortin receptor 5 (MC5R), and Melanocyte-stimulating hormone receptor, Uniprot P32245, P33032, P41968, and Q01726
DOI: 10.7270/q29p326z
title: BindingDB Entry 50035599: Synthesis of 8-amino-3-deazaguanine via imidazole precursors. Antitumor activity and inhibition of purine nucleoside phosphorylase.

description: Small molecule binding data for protein Purine nucleoside phosphorylase, Uniprot P00491
DOI: 10.7270/q2b858wb
title: BindingDB Entry 50037416: Carbonic anhydrase inhibitors. Novel sulfanilamide/acetazolamide derivatives obtained by the tail approach and their interaction with the cytosolic isozymes I and II, and the tumor-associated isozyme IX.

description: Small molecule binding data for protein Carbonic anhydrase, Carbonic anhydrase 2, and Carbonic anhydrase 9, Uniprot P00915, P00918, and Q16790
DOI: 10.7270/q2bp03cs
title: BindingDB Entry 50035586: Functionalized congeners of adenosine: preparation of analogues with high affinity for A1-adenosine receptors.

description: Small molecule binding data for protein Adenosine receptor A1, Uniprot P25099
DOI: 10.7270/q2br8skg
title: BindingDB Entry 50033877: Bioactive prenylogous cannabinoid from fiber hemp (Cannabis sativa).

description: Small molecule binding data for protein Cannabinoid receptor 1, Cannabinoid receptor 2, Transient receptor potential M8 protein (TRPM8), Transient receptor potential cation channel subfamily A member 1, Transient receptor potential cation channel subfamily V member 1, and Vanilloid receptor, Uniprot P21554, P34972, Q6RI86, Q8NER1, Q8R455, and Q9WUD2
DOI: 10.7270/q2cc115v
title: BindingDB Entry 50034759: Cyclic ether acetal platelet activating factor (PAF) receptor antagonists II: imidazo[4,5-c]pyridyl derivatives

description: Small molecule binding data for protein Platelet activating factor receptor, Uniprot P25105
DOI: 10.7270/q2f190gp
title: BindingDB Entry 50037425: 4'C-ethynyl-thymidine acts as a chain terminator during DNA-synthesis catalyzed by HIV-1 reverse transcriptase.

description: Small molecule binding data for protein Human immunodeficiency virus type 1 reverse transcriptase
DOI: 10.7270/q2fb53m9
title: BindingDB Entry 50036517: 7-Spiroindanyl derivatives of naltrexone and oxymorphone as selective ligands for delta opioid receptors.

description: Small molecule binding data for protein Delta-type opioid receptor, Kappa-type opioid receptor, Kappa-type opioid receptor (KOR), and Mu-type opioid receptor, Uniprot P32300, P33534, P35372, P41143, P41145, and P42866
DOI: 10.7270/q2gh9jc3
title: BindingDB Entry 50033876: Fluorinated cannabinoid CB2 receptor ligands: synthesis and in vitro binding characteristics of 2-oxoquinoline derivatives.

description: Small molecule binding data for protein Cannabinoid receptor 1 and Cannabinoid receptor 2, Uniprot P21554 and P34972
DOI: 10.7270/q2h132h9
title: BindingDB Entry 50034758: Cyclic ether acetal platelet activating factor (PAF) receptor antagonists I: 3-pyridyl derivatives

description: Small molecule binding data for protein Platelet activating factor receptor, Uniprot P25105
DOI: 10.7270/q2js9r6q
title: BindingDB Entry 50037424: Carbonic anhydrase inhibitors. Inhibition of the membrane-bound human and bovine isozymes IV with sulfonamides.

description: Small molecule binding data for protein Carbonic Anhydrase IV, Carbonic anhydrase, Carbonic anhydrase 2, and Carbonic anhydrase 4, Uniprot P00915, P00918, P22748, and Q95323
DOI: 10.7270/q2k35v96
title: BindingDB Entry 50036516: Synthesis and structure-activity relationships of a new model of arylpiperazines. 2. Three-dimensional quantitative structure-activity relationships of hydantoin-phenylpiperazine derivatives with affinity for 5-HT1A and alpha 1 receptors. A comparison of CoMFA models.

description: Small molecule binding data for protein Serotonin (5-HT) receptor, Uniprot P19327
DOI: 10.7270/q2k64jnm
title: BindingDB Entry 50035596: Binding requirements of phenolic phenylethylamines in the benzonorbornene skeleton at the active site of phenylethanolamine N-methyltransferase.

description: Small molecule binding data for protein Phenylethanolamine N-methyltransferase, Uniprot P10938
DOI: 10.7270/q2m61ktf
title: BindingDB Entry 50035584: Molecular mechanism of action of 5,6-dihydroxytryptamine. Synthesis and biological evaluation of 4-methyl-, 7-methyl-, and 4,7-dimethyl-5,6-dihydroxytryptamines.

description: Small molecule binding data for protein Sodium-dependent serotonin transporter, Uniprot P31652