cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q2ks6s2h
title: BindingDB Entry 50034766: Aminophosphonate endothelin converting enzyme inhibitors: potency-enhancing and selectivity-improving modifications of phosphoramidon

description: Small molecule binding data for protein Endothelin-converting enzyme 1 and Neutral Endopeptidase (NEP), Uniprot P07861 and P42891
DOI: 10.7270/q2nk3fs6
title: BindingDB Entry 50037431: Synthesis and evaluation of pyrazolidine derivatives as dipeptidyl peptidase IV (DP-IV) inhibitors.

description: Small molecule binding data for protein Dipeptidyl peptidase IV, Uniprot P14740
DOI: 10.7270/q2nv9jwt
title: BindingDB Entry 50036523: Structure-activity relationships of N-hydroxyurea 5-lipoxygenase inhibitors.

description: Small molecule binding data for protein 5-lipoxygenase/FLAP and Arachidonate 5-lipoxygenase, Uniprot P09917 and P12527
DOI: 10.7270/q2nz887n
title: BindingDB Entry 50035607: Inhibition of cathepsin D by substrate analogues containing statine and by analogues of pepstatin.

description: Small molecule binding data for protein Cathepsin D, Pepsin A, and Pepsinogen C, Uniprot P00791, P20142, and P80209
DOI: 10.7270/q2q240md
title: BindingDB Entry 50033883: Lipid and sulfur substituted prenylcysteine analogs as human Icmt inhibitors.

description: Small molecule binding data for protein Isoprenylcysteine carboxyl methyltransferase, Uniprot O60725
DOI: 10.7270/q2qj7hst
title: BindingDB Entry 50034765: Synthesis of coumarins as subtype-selective inhibitors of monoamine oxidase

description: Small molecule binding data for protein Monoamine Oxidase Type B (MAO-B) and Monoamine oxidase, Uniprot P19643 and P21396
DOI: 10.7270/q2sb46hx
title: BindingDB Entry 50037430: cis-6-oxo-hexahydro-2-oxa-1,4-diazapentalene and cis-6-oxo-hexahydropyrrolo[3,2-c]pyrazole based scaffolds: design rationale, synthesis and cysteinyl proteinase inhibition.

description: Small molecule binding data for protein Cathepsin K, Cathepsin S, Cruzipain, and Cysteine proteinase B, Uniprot P25774, P25779, P36400, and P43235
DOI: 10.7270/q2sj1m94
title: BindingDB Entry 50036522: Substituted N-phenylisothioureas: potent inhibitors of human nitric oxide synthase with neuronal isoform selectivity.

description: Small molecule binding data for protein Nitric oxide synthase, brain, Nitric oxide synthase, inducible, and Nitric-oxide synthase (endothelial and brain), Uniprot P29475 and P35228
DOI: 10.7270/q2sq910t
title: BindingDB Entry 50035605: Design and synthesis of conformationally constrained somatostatin analogues with high potency and specificity for mu opioid receptors.

description: Small molecule binding data for protein Nociceptin/mu opioid receptor and Opioid receptors; mu & delta, Uniprot P33533 and P33535
DOI: 10.7270/q2tq61x3
title: BindingDB Entry 50033881: N-Heteroaryl glycinamides and glycinamines as potent NPY5 antagonists.

description: Small molecule binding data for protein Neuropeptide Y receptor type 5 ( NPY Y5), Uniprot Q15761
DOI: 10.7270/q2v988kf
title: BindingDB Entry 50034764: 1,4-substituted indoles: a potent and selective class of angiostensin II receptor antagonists

description: Small molecule binding data for protein Angiotensin II AT1B and Angiotensin II AT2, Uniprot P29089 and P35351
DOI: 10.7270/q2x34z6t
title: BindingDB Entry 50037429: N-i-Propoxy-N-biphenylsulfonylaminobutylhydroxamic acids as potent and selective inhibitors of MMP-2 and MT1-MMP.

description: Small molecule binding data for protein Collagenase, Matrix Metalloproteinase-8 (MMP-8), Matrix metalloproteinase-1 (MMP1), Matrix metalloproteinase-14 (MMP14), Matrix metalloproteinase-7 (MMP7), and Stromelysin-1, Uniprot P03956, P08253, P08254, P09237, P14780, P22894, and P50281
DOI: 10.7270/q2x92bzj
title: BindingDB Entry 50036521: Discovery and biological activity of orally active peptidyl trifluoromethyl ketone inhibitors of human neutrophil elastase.

description: Small molecule binding data for protein Leukocyte elastase, Uniprot P08246
DOI: 10.7270/q2xg9rqr
title: BindingDB Entry 50035604: Azasteroids: structure-activity relationships for inhibition of 5 alpha-reductase and of androgen receptor binding.

description: Small molecule binding data for protein Androgen receptor, Uniprot P15207
DOI: 10.7270/q2zg6sm0
title: BindingDB Entry 50033880: Synthesis and preliminary evaluation of a modified estradiol-core bearing a fused¿-lactone as non-estrogenic inhibitor of 17ß-hydroxysteroid dehydrogenase type 1.

description: Small molecule binding data for protein Estradiol 17-beta-dehydrogenase 1 (17beta-HSD1), Uniprot P14061
DOI: 10.7270/q2057gkd
title: BindingDB Entry 50036539: beta-Methylation of the Phe7 and Trp9 melanotropin side chain pharmacophores affects ligand-receptor interactions and prolonged biological activity.

description: Small molecule binding data for protein Melanocyte-stimulating hormone receptor, Uniprot Q01726
DOI: 10.7270/q20v8djd
title: BindingDB Entry 50037436: Design, synthesis, biological evaluation and molecular docking of curcumin analogues as antioxidant, cyclooxygenase inhibitory and anti-inflammatory agents.

description: Small molecule binding data for protein Cyclooxygenase, Prostaglandin G/H synthase (Cyclooxygenase-2), and Prostaglandin G/H synthase (cyclooxygenase), Uniprot P05979, P35354, and P79208
DOI: 10.7270/q21836wz
title: BindingDB Entry 50033899: Pantolactams as androgen receptor antagonists for the topical suppression of sebum production.

description: Small molecule binding data for protein Androgen Receptor, Uniprot P10275
DOI: 10.7270/q218372m
title: BindingDB Entry 50035614: Angiotensin converting enzyme inhibitors as antihypertensive agents: 1-[(2-mercaptocycloalkyl)carbonyl]-L-prolines.

description: Small molecule binding data for protein Angiotensin-converting enzyme, Uniprot P47820
DOI: 10.7270/q21v5ffn
title: BindingDB Entry 50034779: Potent glycosidase inhibitors, N-phenyl cyclic isourea derivatives of 5-amino- and 5-amino-1-C-(hydroxymethyl)-cyclopentane-1,2,3,4-tetraols

description: Small molecule binding data for protein Alpha-glucosidase, Glucocerebrosidase (Acid beta-Glucosidase), and Lysosomal alpha-glucosidase, Uniprot P04062, P10253, and Q9MYM4
DOI: 10.7270/q23n245r
title: BindingDB Entry 50037443: Studies on the reactivity of CDDO, a promising new chemopreventive and chemotherapeutic agent: implications for a molecular mechanism of action.

description: Small molecule binding data for protein Nitric oxide synthase, inducible, Uniprot P35228
DOI: 10.7270/q24x58c9
title: BindingDB Entry 50035613: Synthesis and biological evaluation of 1-(1,2-benzisothiazol-3-yl)- and (1,2-benzisoxazol-3-yl)piperazine derivatives as potential antipsychotic agents.

description: Small molecule binding data for protein Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor, GABA receptor gamma-1 subunit, Histamine H1 receptor, and Metabotropic glutamate receptor 3 (mGlu3), Uniprot P23574, P31390, P31422, and P61169
DOI: 10.7270/q27d2vwp
title: BindingDB Entry 50037442: Synthesis and evaluation of potential inhibitors of eIF4E cap binding to 7-methyl GTP.

description: Small molecule binding data for protein Eukaryotic translation initiation factor 4E (eIF4E), Uniprot P06730
DOI: 10.7270/q27m08mc
title: BindingDB Entry 50036537: Mutagenesis reveals structure-activity parallels between human A2A adenosine receptors and biogenic amine G protein-coupled receptors.

description: Small molecule binding data for protein Adenosine receptor A2a, Uniprot P29274
DOI: 10.7270/q28p612k
title: BindingDB Entry 50035612: Ribose-modified adenosine analogues as adenosine receptor agonists.

description: Small molecule binding data for protein Adenosine receptor A1, Uniprot P25099
DOI: 10.7270/q28s4q8t
title: BindingDB Entry 50033896: Synthesis, molecular modeling and biological evaluation of chalcone thiosemicarbazide derivatives as novel anticancer agents.

description: Small molecule binding data for protein Epidermal growth factor receptor, Uniprot P00533
DOI: 10.7270/q29c6xxr
title: BindingDB Entry 50034777: Peptidomimetic inhibitors of p21ras farnesyltransferase: Hydrophobic functionalization leads to disruption of p21ras membrane association in whole cells

description: Small molecule binding data for protein Protein Farnesyltransferase (PFT), Uniprot P49354 and P49356
DOI: 10.7270/q2bc401g
title: BindingDB Entry 50034768: L-161,638: A potent AT2selective quinazolinone angiotensin II binding inhibitor

description: Small molecule binding data for protein Angiotensin II AT2, Angiotensin II receptor, and Angiotensin II type 1a (AT-1a) receptor, Uniprot P34976, P35351, and P50052
DOI: 10.7270/q2c24x63
title: BindingDB Entry 50037441: Synthesis and opioid receptor binding properties of a highly potent 4-hydroxy analogue of naltrexone.

description: Small molecule binding data for protein Delta-type opioid receptor, Kappa-type opioid receptor, and Mu-type opioid receptor, Uniprot P35372, P41143, and P41145
DOI: 10.7270/q2cc11cj
title: BindingDB Entry 50036536: The role of phenylalanine at position 6 in glucagon's mechanism of biological action: multiple replacement analogues of glucagon.

description: Small molecule binding data for protein Glucagon receptor, Uniprot P30082
DOI: 10.7270/q2df6rsh
title: BindingDB Entry 50035611: Isozyme-specific enzyme inhibitors. 10. Adenosine 5'-triphosphate derivatives as substrates or inhibitors of methionine adenosyltransferases of rat normal and hepatoma tissues.

description: Small molecule binding data for protein S-adenosylmethionine synthetase (MAT 1 and MAT 2), Uniprot P13444 and P18298
DOI: 10.7270/q2dj5g0j
title: BindingDB Entry 50033895: Strategies to lower the Pgp efflux liability in a series of potent indole azetidine MCHR1 antagonists.

description: Small molecule binding data for protein GPR24 and Voltage-gated potassium channel, Uniprot Q12809
DOI: 10.7270/q2f47png
title: BindingDB Entry 50034776: Differential binding and dopamine uptake activity of cocaine analogues modified at nitrogen

description: Small molecule binding data for protein Monoamine transporters; Norepininephrine & dopamine, Uniprot P23977
DOI: 10.7270/q2gt5nx3
title: BindingDB Entry 50037440: 2-(Arylmethyl)-3-substituted quinuclidines as selective alpha 7 nicotinic receptor ligands.

description: Small molecule binding data for protein Neuronal acetylcholine receptor and Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit, Uniprot P17787, P43681, and Q05941
DOI: 10.7270/q2h41s4b
title: BindingDB Entry 50036535: Synthesis of nonhydrolyzable analogues of thiazole-4-carboxamide and benzamide adenine dinucleotide containing fluorine atom at the C2' of adenine nucleoside: induction of K562 differentiation and inosine monophosphate dehydrogenase inhibitory activity.

description: Small molecule binding data for protein Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2), Uniprot P12268
DOI: 10.7270/q2h70gcd
title: BindingDB Entry 50035619: Thromboxane synthetase inhibitors and antihypertensive agents. 2. N-[(1H-imidazol-1-yl)alkyl]-1H-isoindole-1,3(2H)-diones and N-[(1H-1,2,4-triazol-1-yl)alkyl]-1H-isoindole-1,3(2H)-diones as unique antihypertensive agents.

description: Small molecule binding data for protein Thromboxane-A synthase, Uniprot P49430
DOI: 10.7270/q2j966r9
title: BindingDB Entry 50033894: Identification of a non-phosphorylated, cell permeable, small molecule ligand for the Stat3 SH2 domain.

description: Small molecule binding data for protein Signal transducer and activator of transcription 1, Signal transducer and activator of transcription 3, and Transcription Factor STAT3, Uniprot P40763, P42225, and P42227
DOI: 10.7270/q2jw8fcw
title: BindingDB Entry 50034775: 16-propyl derivatives of estradiol as inhibitors of 17-hydroxysteroid dehydrogenase type 1

description: Small molecule binding data for protein Estradiol 17-beta-dehydrogenase 1 (17beta-HSD1), Uniprot P14061
DOI: 10.7270/q2mk6dnt
title: BindingDB Entry 50037439: 2-Piperazinecarboxamides as potent and selective melanocortin subtype-4 receptor agonists.

description: Small molecule binding data for protein Melanocortin receptor 3 (MC3R), Melanocortin receptor 4, and Melanocortin receptor 5 (MC5R), Uniprot P32245, P33032, and P41968
DOI: 10.7270/q2mw2hvb
title: BindingDB Entry 50036534: Synthesis and ligand binding studies of 4'-iodobenzoyl esters of tropanes and piperidines at the dopamine transporter.

description: Small molecule binding data for protein Dopamine Transporter (DAT), Uniprot P23977
DOI: 10.7270/q2n01734
title: BindingDB Entry 50035618: Synthesis and biological properties of chitin synthetase inhibitors resistant to cellular peptidases.

description: Small molecule binding data for protein Chitin synthase, Uniprot P23316
DOI: 10.7270/q2p26zh3
title: BindingDB Entry 50033893: Structure-based design and synthesis of 1,3-oxazinan-2-one inhibitors of 11ß-hydroxysteroid dehydrogenase type 1.

description: Small molecule binding data for protein 11-beta-hydroxysteroid dehydrogenase 1, 11-beta-hydroxysteroid dehydrogenase 2, 3-beta-hydroxysteroid dehydrogenase/delta 5--&gt;4-isomerase type II, Bile acid receptor FXR, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), Cytochrome P450 3A, Estradiol 17-beta-dehydrogenase 1 (17beta-HSD1), Glucocorticoid receptor, Mineralocorticoid receptor (MR), and Voltage-gated potassium channel, Uniprot P04150, P08235, P08684, P10635, P11712, P14061, P26439, P28845, P50172, P80365, Q12809, and Q96RI1
DOI: 10.7270/q2pk0gn0
title: BindingDB Entry 50034774: 3-Hydroxy-19-nor-17-pregna-1,3,5(10)-triene-21,17-carbolactone as inhibitor of 17-hydroxysteroid dehydrogenase type 2

description: Small molecule binding data for protein Estradiol 17-beta-dehydrogenase 2, Uniprot P37059
DOI: 10.7270/q2rb75cj
title: BindingDB Entry 50037438: Design, synthesis, and structure-activity relationships of tetrahydroquinoline-based farnesyltransferase inhibitors.

description: Small molecule binding data for protein Protein Farnesyltransferase (PFT) and Protein Farnesyltransferase (PFT)/farnesyltransferase beta subunit, Uniprot P49354, P49356, Q02293, and Q04631
DOI: 10.7270/q2rn38jm
title: BindingDB Entry 50036533: Selective inhibitors of monoamine oxidase. 4. SAR of tricyclic N-methylcarboxamides and congeners binding at the tricyclics' hydrophilic binding site.

description: Small molecule binding data for protein Monoamine Oxidase Type B (MAO-B) and Monoamine oxidase, Uniprot P19643 and P21396
DOI: 10.7270/q2rr1ztr
title: BindingDB Entry 50035617: Methotrexate analogues. 26. Inhibition of dihydrofolate reductase and folylpolyglutamate synthetase activity and in vitro tumor cell growth by methotrexate and aminopterin analogues containing a basic amino acid side chain.

description: Small molecule binding data for protein Dihydrofolate reductase and Folylpoly-gamma-glutamate synthetase, Uniprot P00375 and P48760
DOI: 10.7270/q2st7q62
title: BindingDB Entry 50033892: Discovery of a tetrahydroisoquinoline-based hydroxamic acid derivative (ZYJ-34c) as histone deacetylase inhibitor with potent oral antitumor activities.

description: Small molecule binding data for protein Histone deacetylase and Histone deacetylase 8, Uniprot A0A024QZ26, Q9BY41, and Q9UBN7
DOI: 10.7270/q2tb17cq
title: BindingDB Entry 50034773: Synthesis and glutamate antagonist activity of 4-phosphonoalkylquinoline derivatives: A novel class of non-NMDA antagonist

description: Small molecule binding data for protein Glutamate-NMDA, Uniprot P35439
DOI: 10.7270/q2w37x3w
title: BindingDB Entry 50037437: Fused pyrimidine based inhibitors of phosphodiesterase 7 (PDE7): synthesis and initial structure-activity relationships.

description: Small molecule binding data for protein Phosphodiesterase 3 and cGMP-dependent 3',5'-cyclic phosphodiesterase, Uniprot O00408, Q13370, and Q14432
DOI: 10.7270/q2wd417w
title: BindingDB Entry 50036532: An orally bioavailable pyrrolinone inhibitor of HIV-1 protease: computational analysis and X-ray crystal structure of the enzyme complex.

description: Small molecule binding data for protein Human immunodeficiency virus type 1 protease
DOI: 10.7270/q2wh2qkx
title: BindingDB Entry 50035616: N-substituent modulation of opiate agonist/antagonist activity in resolved 3-methyl-3-(m-hydroxyphenyl)piperidines.

description: Small molecule binding data for protein Nociceptin/mu opioid receptor, Opioid receptor, and Opioid receptors; mu & delta, Uniprot P33533, P33535, and P34975
DOI: 10.7270/q2xg9rjh
title: BindingDB Entry 50033891: Combination of pharmacophore model development and binding mode analyses: identification of ligand features essential for I¿B kinase-beta (IKKß) inhibitors and virtual screening based on it.

description: Small molecule binding data for protein Inhibitor of NF-kappa-B kinase (IKK), Uniprot O14920
DOI: 10.7270/q2z3204w
title: BindingDB Entry 50034771: Mercaptoacyl dipeptides as dual inhibitors of angiotensin-converting enzyme and neutral endopeptidase. Preliminary structure-activity studies

description: Small molecule binding data for protein Angiotensin-converting enzyme and Neutral Endopeptidase (NEP), Uniprot P07861 and P12822
DOI: 10.7270/q20865wc
title: BindingDB Entry 50035623: Synthesis and rat lens aldose reductase inhibitory activity of some benzopyran-2-ones.

description: Small molecule binding data for protein Aldose reductase, Uniprot P07943
DOI: 10.7270/q20c4w5x
title: BindingDB Entry 50033908: Hybrids of oxoisoaporphine-tacrine congeners: novel acetylcholinesterase and acetylcholinesterase-inducedß-amyloid aggregation inhibitors.

description: Small molecule binding data for protein Acetylcholinesterase and Butyrylcholinesterase (BuChE), Uniprot O42275 and P81908
DOI: 10.7270/q20v8d8t
title: BindingDB Entry 50034789: N-chloromethyl quinuclidinium derivatives: A new class of irreversible ligands for 5-HT3 receptors.

description: Small molecule binding data for protein Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor, Uniprot P35563 and Q9JJ16
DOI: 10.7270/q22n532t
title: BindingDB Entry 50037452: Liver-selective glucocorticoid antagonists: a novel treatment for type 2 diabetes.

description: Small molecule binding data for protein Androgen Receptor, Estradiol receptor alpha (ERα), Estradiol receptor beta (ERβ), Glucocorticoid receptor, Mineralocorticoid receptor (MR), Progesterone receptor, Thyroid Hormone Receptor (TR-beta), and Thyroid hormone receptor, Uniprot F1D8N7, P03372, P04150, P06401, P08235, P10275, P10827, P10828, and Q92731
DOI: 10.7270/q22z166f
title: BindingDB Entry 50036547: Curcumin analogs with altered potencies against HIV-1 integrase as probes for biochemical mechanisms of drug action.

description: Small molecule binding data for protein Human immunodeficiency virus type 1 integrase
DOI: 10.7270/q23t9hxj
title: BindingDB Entry 50036538: 2-Carbomethoxy-3-aryl-8-oxabicyclo[3.2.1]octanes: potent non-nitrogen inhibitors of monoamine transporters.

description: Small molecule binding data for protein Serotonin and norepinephrine transporters (SERT/NET) and Sodium-dependent dopamine transporter, Uniprot P31645 and Q01959
DOI: 10.7270/q2416xmq
title: BindingDB Entry 50035622: Syntheses and antifolate activity of 5-methyl-5-deaza analogues of aminopterin, methotrexate, folic acid, and N10-methylfolic acid.

description: Small molecule binding data for protein Dihydrofolate reductase, Uniprot P00375
DOI: 10.7270/q24m9510
title: BindingDB Entry 50034788: Pyrazolo[1,5-a]pyridines and pyrazolo[1,5-b]pyridazines as 5ht3-antagonists

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 1A, Dopamine receptor D2L/neurotensin receptor NTS1, and Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor, Uniprot P08908, P14416, P35563, and Q9JJ16
DOI: 10.7270/q2513zkv
title: BindingDB Entry 50033897: Identification and characterization of a novel integrin-linked kinase inhibitor.

description: Small molecule binding data for protein Serine/threonine-protein kinase ILK-1, Uniprot Q13418
DOI: 10.7270/q25m666t
title: BindingDB Entry 50034778: EPSP synthase inhibitor design IV. New aromatic substrate analogs and symmetrical inhibitors containing novel 3-phosphate mimics.

description: Small molecule binding data for protein 5-enolpyruvylshikimate-3-phosphate synthase, Uniprot P0A6D3
DOI: 10.7270/q26d5tr9
title: BindingDB Entry 50037451: Synthesis and biological activity of new potential agonists for the human adenosine A2A receptor.

description: Small molecule binding data for protein Adenosine Receptors A2a (A2a), Adenosine receptor A1, Adenosine receptor A2a, Adenosine receptor A2b, and Adenosine receptor A3, Uniprot P0DMS8, P29274, P29275, P30542, and P30543
DOI: 10.7270/q26m37hf
title: BindingDB Entry 50036545: Ras farnesyltransferase: a new therapeutic target.

description: Small molecule binding data for protein Geranylgeranyl transferase type I beta subunit/Protein Farnesyltransferase (PFT), Protein Farnesyltransferase (PFT), Protein Farnesyltransferase (PFT)/farnesyltransferase beta subunit, and Protein farnesyltransferase beta/geranylgeranyltransferase type I alpha subunit, Uniprot P22007, P29702, P29703, P49354, P49355, P49356, P53609, Q02293, Q04631, Q61239, and Q8K2I1
DOI: 10.7270/q27p8zzv
title: BindingDB Entry 50035621: Synthesis and alpha-D-glucosidase inhibitory activity of N-substituted valiolamine derivatives as potential oral antidiabetic agents.

description: Small molecule binding data for protein Maltase-glucoamylase and Sucrase-isomaltase, Uniprot O43451 and P14410
DOI: 10.7270/q27s7p5w
title: BindingDB Entry 50033906: Derivatives of pyrrolo[3,4-d]pyridazinone, a new class of analgesic agents.

description: Small molecule binding data for protein Nociceptin/mu opioid receptor, Uniprot P33535
DOI: 10.7270/q28c9wrx
title: BindingDB Entry 50034787: EMD 61 753 as a favourable representative of structurally novel arylacetamido-type K opiate receptor agonists

description: Small molecule binding data for protein Nociceptin/mu opioid receptor, Opioid receptors; mu & delta, and mu/kappa opioid receptor, Uniprot P33533, P33535, and P41144
DOI: 10.7270/q2b56kg1
title: BindingDB Entry 50037450: Substituted 3-imidazo[1,2-a]pyridin-3-yl- 4-(1,2,3,4-tetrahydro-[1,4]diazepino-[6,7,1-hi]indol-7-yl)pyrrole-2,5-diones as highly selective and potent inhibitors of glycogen synthase kinase-3.

description: Small molecule binding data for protein AKT/p21CIP1, Cyclin-dependent kinase 2, Cyclin-dependent kinase 4, Glycogen synthase kinase-3, Mixed lineage kinase 7, PKC alpha and beta-2, Pyruvate dehydrogenase kinase isoenzyme 1 (PDK1), TGF-beta receptor type II, Vascular endothelial growth factor receptor 2, and cAMP-dependent protein kinase (PKA), Uniprot P05771, P11802, P22694, P24941, P31749, P35968, P37173, P49841, Q15118, and Q9NYL2
DOI: 10.7270/q2bc406q
title: BindingDB Entry 50036544: Synthesis and pharmacological activity of deltorphin and dermorphin-related glycopeptides.

description: Small molecule binding data for protein Nociceptin/mu opioid receptor and Opioid receptors; mu & delta, Uniprot P33533 and P33535
DOI: 10.7270/q2bg2pk6
title: BindingDB Entry 50035631: Folate analogues. 25. Synthesis and biological evaluation of N10-propargylfolic acid and its reduced derivatives.

description: Small molecule binding data for protein Dihydrofolate reductase, Thymidylate Synthase (TS), and Thymidylate synthase, Uniprot P00381, P00469, and P07607
DOI: 10.7270/q2cf9qn4
title: BindingDB Entry 50035620: Isozyme-specific enzyme inhibitors. 11. L-homocysteine-ATP S-C5' covalent adducts as inhibitors of rat methionine adenosyltransferases.

description: Small molecule binding data for protein S-adenosylmethionine synthetase (MAT 1 and MAT 2), Uniprot P18298
DOI: 10.7270/q2cj8dvr
title: BindingDB Entry 50033905: 4-benzimidazolyl-3-phenylbutanoic acids as novel PIF-pocket-targeting allosteric inhibitors of protein kinase PKC¿.

description: Small molecule binding data for protein Protein kinase C (PKC), Uniprot Q05513
DOI: 10.7270/q2d50ng6
title: BindingDB Entry 50034786: Synthesis of RPR 100893, prototype of a new series of potent and selective non peptide NK1 antagonists : the triarylperhydroisoindolols.

description: Small molecule binding data for protein Neurokinin 1 receptor, Uniprot P25103