cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.20551410.v1
title: MicroRNA-124a Protects the Myocardium Against Ischemia Reperfusion Injury Through Regulation of the Notch Signaling Pathway

description: Abstract Introduction: This study’s objective is to investigate the effect of downregulation of micro ribonucleic acid (miR)-124a on myocardial injury after ischemia reperfusion (I/R) in rats. Methods: Sprague Dawley (SD) rats (n=20) were divided into four groups - sham, I/R, I/R+miR-124a antagomir (I/R+ant-miR-124a), and I/R+ant-normal control (NC). The pathomorphological and infarct size variance of injured myocardial tissues with IR were conducted with hematoxylin (HE) and triphenyltetrazolium chloride (TTC) staining. The expression levels of miR-124a, BAX, nuclear factor kappa B (NF-KB), Notch1, and Hes1 were examined by quantitative real-time polymerase chain reaction or Western blot in myocardium. The inflammatory cytokines interleukin (IL)-6, IL-1β, and tumor necrosis factor alpha (TNF-α) were detected by the enzyme-linked immunosorbent assay, as well as the activity of lactate dehydrogenase (LDH) and creatine kinase (CK) in serum by colorimetry. Results: The expression of miR-124a was increased in the I/R group. Compared with I/R and I/R+ant-NC groups, after downregulating miR-124a, the expression of IL-6, IL-1β, TNF-α, BAX, NF-KB, LDH, and CK were decreased, but the expression of Notch1 and Hes1 were increased. In HE staining, myocardial tissue edema, red blood cell exudation, and myocardial fiber arrangement disorder were accompanied by inflammatory cell infiltration and local necrosis in the I/R group. However, the pathological injury of myocardial tissue was alleviated after downregulating miR-124a. Additionally, TTC results showed that the myocardial infarction area was decreased in the I/R+ant-miR-124a group. Conclusion: Downregulation of miR-124a expression through Notch pathway can significantly reduce myocardial damage after 24 hours of I/R in SD rats. Therefore, miR-124a may become a potential therapeutic target for I/R injury.
DOI: 10.6084/m9.figshare.12004557.v1
title: Additional file 1 of Dynamic LTR retrotransposon transcriptome landscape in septic shock patients

description: Additional file 1 : Table S1. The HERV transcriptome in whole blood samples (descriptive phase).
DOI: 10.6084/m9.figshare.20551663
title: Long Noncoding RNA AF131217.1 Regulated Coronary Slow Flow-Induced Inflammation Affecting Coronary Slow Flow via KLF4

description: Abstract Introduction: This study investigated the correlation between the levels of long noncoding ribonucleic acids (lncRNAs) AF131217.1 and coronary slow flow (CSF). Methods: A total of 22 patients in the high-sensitivity C-reactive protein (hsCRP) group diagnosed with CSF from January 2018 to December 2018 were enrolled in this study. Coronary flow velocity was determined using the thrombolysis in myocardial infarction frame count (TFC) method. Results: LncRNA AF131217.1 expression in the CSF model was activated. Mean TFC was positively correlated with lncRNA AF131217.1 levels and hsCRP levels. LncRNA AF131217.1 induced inflammation factor levels in the in vitro model. Micro ribonucleic acid (miR)-128-3p is a target spot of lncRNA AF131217.1 on the inflammation in vitro model via Kruppel-like factor (KLF) 4. MiR-128-3p reduced inflammation factor levels (tumor necrosis factor alpha, interleukin [IL]-6, IL-1β, and IL-18). Conclusion: Thus, lncRNA AF131217.1 promoted inflammation in the regulated CSF via KLF4 by miR-128-3p.
DOI: 10.25549/usctheses-c3-599898
title: etd-RuizSusana-3651~055
DOI: 10.25549/usctheses-c3-599869
title: etd-RuizSusana-3651~026
DOI: 10.6084/m9.figshare.20551933
title: QUANTITATIVE ANALYSIS AND HYPERSPECTRAL REMOTE SENSING INVERSION OF RICE CANOPY SPAD IN A COLD REGION

description: ABSTRACT This study used a spectral index method and an artificial intelligence algorithm to quantitatively analyze rice canopy soil and plant analyzer development (SPAD) based on ground nonimaging spectral data and UAV hyperspectral images to build a high-precision SPAD prediction model for nondestructive monitoring of the chlorophyll relative content of rice in cold regions. First, this study First, this study selected characteristic bands sensitive to SPAD using uninformative variable elimination and the successive projections algorithm. Then, the correlation between commonly used vegetation indices and SPAD was analyzed. Finally, this study constructed a back propagation neural network (BPNN) model, BPNN with particle swarm optimization (PSO-BPNN) model, and BPNN with genetic algorithm optimization (GA-BPNN) model, and then verified the reliability of these models. According to the results, GA-BPNN had the best predictive effect. The coefficient of the determination reached 0.818, and the root mean square error was 0.847. GA-BPNN model combined with UAV hyperspectral images were used for inversion mapping; the predicted range of SPAD was 33.1–41.2, which is in good agreement with the measured value (32.7–40.6). The inversion of regional rice canopy SPAD by nonimaging spectral data and UAV hyperspectral images had high credibility, which provided technical support for the scientific management of rice in a cold region.
DOI: 10.25549/usctheses-c3-599925
title: etd-RuizSusana-3651~082
DOI: 10.6084/m9.figshare.19501228
title: Additional file 1 of Genome-wide survey of the GATA gene family in camptothecin-producing plant Ophiorrhiza pumila

description: Additional file 1.
DOI: 10.25549/usctheses-c3-601222
title: etd-GaddisMala-3657~03
DOI: 10.6084/m9.figshare.12004557
title: Additional file 1 of Dynamic LTR retrotransposon transcriptome landscape in septic shock patients

description: Additional file 1 : Table S1. The HERV transcriptome in whole blood samples (descriptive phase).
DOI: 10.6084/m9.figshare.19501234
title: Additional file 3 of Genome-wide survey of the GATA gene family in camptothecin-producing plant Ophiorrhiza pumila

description: Additional file 3.
DOI: 10.6084/m9.figshare.19501243
title: Additional file 6 of Genome-wide survey of the GATA gene family in camptothecin-producing plant Ophiorrhiza pumila

description: Additional file 6.
DOI: 10.25549/usctheses-c3-589769
title: etd-ChiuCathle-3452~101
DOI: 10.6084/m9.figshare.19501246
title: Additional file 7 of Genome-wide survey of the GATA gene family in camptothecin-producing plant Ophiorrhiza pumila

description: Additional file 7.
DOI: 10.6084/m9.figshare.12687142.v1
title: Additional file 4 of Identification of resistance loci in Chinese and Canadian canola/rapeseed varieties against Leptosphaeria maculans based on genome-wide association studies

description: Additional file 4.
DOI: 10.25549/usctheses-c3-577161
title: etd-CardenasMi-3510_053
DOI: 10.6084/m9.figshare.14782731.v1
title: Additional file 3 of Reversible GABAergic dysfunction involved in hippocampal hyperactivity predicts early-stage Alzheimer disease in a mouse model

description: Additional file 3: Supplementary Table S2.
DOI: 10.6084/m9.figshare.14782728.v1
title: Additional file 2 of Reversible GABAergic dysfunction involved in hippocampal hyperactivity predicts early-stage Alzheimer disease in a mouse model

description: Additional file 2: Supplementary Table S1.
DOI: 10.6084/m9.figshare.16879930
title: Additional file 4 of Chitosan oligosaccharides packaged into rat adipose mesenchymal stem cells-derived extracellular vesicles facilitating cartilage injury repair and alleviating osteoarthritis

description: Additional file 4: Table S1. The differentially expressed genes (DEGs) in at least two comparison groups.
DOI: 10.25549/usctheses-c3-589756
title: etd-ChiuCathle-3452~088
DOI: 10.6084/m9.figshare.14782731
title: Additional file 3 of Reversible GABAergic dysfunction involved in hippocampal hyperactivity predicts early-stage Alzheimer disease in a mouse model

description: Additional file 3: Supplementary Table S2.
DOI: 10.25549/usctheses-c3-601233
title: etd-GaddisMala-3657~14
DOI: 10.6084/m9.figshare.16879930.v1
title: Additional file 4 of Chitosan oligosaccharides packaged into rat adipose mesenchymal stem cells-derived extracellular vesicles facilitating cartilage injury repair and alleviating osteoarthritis

description: Additional file 4: Table S1. The differentially expressed genes (DEGs) in at least two comparison groups.
DOI: 10.25549/usctheses-c3-589741
title: etd-ChiuCathle-3452~073
DOI: 10.25549/usctheses-c3-577194
title: etd-CardenasMi-3510_086
DOI: 10.25549/usctheses-c3-577212
title: etd-CardenasMi-3510_104
DOI: 10.25549/usctheses-c3-577172
title: etd-CardenasMi-3510_064
DOI: 10.25549/usctheses-c3-589681
title: etd-ChiuCathle-3452~013
DOI: 10.6084/m9.figshare.16879933.v1
title: Additional file 5 of Chitosan oligosaccharides packaged into rat adipose mesenchymal stem cells-derived extracellular vesicles facilitating cartilage injury repair and alleviating osteoarthritis

description: Additional file 5: Table S2. DEGs in each cluster used for biological process and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analyses.
DOI: 10.25549/usctheses-c3-589724
title: etd-ChiuCathle-3452~056
DOI: 10.25549/usctheses-c3-589765
title: etd-ChiuCathle-3452~097
DOI: 10.25549/usctheses-c3-599934
title: etd-RuizSusana-3651~091
DOI: 10.25549/usctheses-c3-601315
title: etd-GaddisMala-3657~96
DOI: 10.25549/usctheses-c3-577165
title: etd-CardenasMi-3510_057
DOI: 10.25549/usctheses-c3-589690
title: etd-ChiuCathle-3452~022
DOI: 10.25549/usctheses-c3-577135
title: etd-CardenasMi-3510_027
DOI: 10.25549/usctheses-c3-589718
title: etd-ChiuCathle-3452~050
DOI: 10.25549/usctheses-c3-601292
title: etd-GaddisMala-3657~73
DOI: 10.25549/usctheses-c3-577110
title: etd-CardenasMi-3510_002
DOI: 10.6084/m9.figshare.19503047
title: Enhancing integrated denitrifying anaerobic methane oxidation and Anammox processes for nitrogen and methane removal: A review

description: The integration of denitrifying anaerobic methane oxidation (DAMO) and anaerobic ammonium oxidation (Anammox) simultaneously converts ammonium, methane, and oxidized nitrogen species (nitrite and nitrate) to harmless N<sub>2</sub> and CO<sub>2</sub>. This integrated and complementary process achieves the nitrogen and carbon cycles in wastewater with the potential to be applied widely at full scale to realize energy-positive wastewater treatment plants (WWTPs). In this review, we summarize the collaborative and competitive interactions of DAMO–Anammox microorganisms and systematically evaluate the challenges for the full-scale application of integrated DAMO–Anammox for wastewater treatment, including their extremely slow growth rate, low metabolic activity, and limited nitrogen and methene removal rate. We examine comprehensively the critical role of bioreactor design (attached, suspended, and granular sludge systems) for biomass retention and substrate transfer. The paper also discussed strategies involving trace elements (Cu(II) and Fe(II)), Zero Valent Iron (ZVI), and External Electrostatic Fields (EEFs) to enhance the DAMO–Anammox microbial activities. Further review is provided on the addition of Humics, quinone-compound anthraquinone-2,6-disulfonate (AQDs), Fe(III), Mn(IV) as electron acceptors through extracellular electron transfer (EET) and couple with autotrophic denitrification (AuDen) (H<sub>2</sub>S and Fe(II)) to accelerate nitrogen and methane removal. Finally, a conceptual design of innovative WWTPs based on the integrated DAMO–Anammox was proposed.
DOI: 10.25549/usctheses-c3-599962
title: etd-RuizSusana-3651~119
DOI: 10.25549/usctheses-c3-589698
title: etd-ChiuCathle-3452~030
DOI: 10.25549/usctheses-c3-589746
title: etd-ChiuCathle-3452~078
DOI: 10.25549/usctheses-c3-589764
title: etd-ChiuCathle-3452~096
DOI: 10.25549/usctheses-c3-589759
title: etd-ChiuCathle-3452~091
DOI: 10.25549/usctheses-c3-589715
title: etd-ChiuCathle-3452~047
DOI: 10.25549/usctheses-c3-601307
title: etd-GaddisMala-3657~88
DOI: 10.25549/usctheses-c3-577196
title: etd-CardenasMi-3510_088
DOI: 10.25549/usctheses-c3-600001
title: etd-RuizSusana-3651~158
DOI: 10.25549/usctheses-c3-601264
title: etd-GaddisMala-3657~45
DOI: 10.25549/usctheses-c3-601240
title: etd-GaddisMala-3657~21
DOI: 10.25549/usctheses-c3-599989
title: etd-RuizSusana-3651~146
DOI: 10.25549/usctheses-c3-577184
title: etd-CardenasMi-3510_076
DOI: 10.6084/m9.figshare.20551663.v1
title: Long Noncoding RNA AF131217.1 Regulated Coronary Slow Flow-Induced Inflammation Affecting Coronary Slow Flow via KLF4

description: Abstract Introduction: This study investigated the correlation between the levels of long noncoding ribonucleic acids (lncRNAs) AF131217.1 and coronary slow flow (CSF). Methods: A total of 22 patients in the high-sensitivity C-reactive protein (hsCRP) group diagnosed with CSF from January 2018 to December 2018 were enrolled in this study. Coronary flow velocity was determined using the thrombolysis in myocardial infarction frame count (TFC) method. Results: LncRNA AF131217.1 expression in the CSF model was activated. Mean TFC was positively correlated with lncRNA AF131217.1 levels and hsCRP levels. LncRNA AF131217.1 induced inflammation factor levels in the in vitro model. Micro ribonucleic acid (miR)-128-3p is a target spot of lncRNA AF131217.1 on the inflammation in vitro model via Kruppel-like factor (KLF) 4. MiR-128-3p reduced inflammation factor levels (tumor necrosis factor alpha, interleukin [IL]-6, IL-1β, and IL-18). Conclusion: Thus, lncRNA AF131217.1 promoted inflammation in the regulated CSF via KLF4 by miR-128-3p.
DOI: 10.25549/usctheses-c3-589721
title: etd-ChiuCathle-3452~053
DOI: 10.25549/usctheses-c3-577181
title: etd-CardenasMi-3510_073
DOI: 10.6084/m9.figshare.14260192.v1
title: Identification of differential DNA methylation alterations of ovarian cancer in peripheral whole blood based on within-sample relative methylation orderings

description: Leukocyte cell proportion changes affect the detection of cancer-associated aberrant DNA methylation alterations in peripheral blood samples. We aimed to detect cellular DNA methylation changes in ovarian cancer (OVC) blood samples avoiding the above-mentioned cell-composition effects. Based on the within-sample relative methylation orderings (RMOs) of CpG loci in leukocyte subtypes, we developed the Ref-RMO method to detect aberrant methylation alterations from OVC blood samples. Stable CpG pairs with consistent RMOs in different leukocyte subtypes were determined, more than 99% of which retained their RMO patterns in peripheral whole blood (PWB) in independent datasets. Based on the stable CpG pairs, significantly reversed CpG pairs were detected from OVC PWB samples, which were relative to clinical information such as age, subtype, grade, stage, or CA125 level. Results showed 439 CpG loci were determined to be significant differential DNA methylations between OVC and healthy blood samples. They were mainly enriched in KEGG pathways, such as cytokine-cytokine receptor interaction, apoptosis, proteoglycans in cancer, and immune-associated Gene Ontology terms. STRING analysis showed that they tended to have functional interactions with cancer-associated genes recorded in the COSMIC database. Leukocyte cellular differential DNA methylations could be identified by the proposed RMO-based method from OVC PWB samples, which were cancer-associated aberrant signals against cell-composition effects.
DOI: 10.25549/usctheses-c3-599914
title: etd-RuizSusana-3651~071
DOI: 10.25549/usctheses-c3-589772
title: etd-ChiuCathle-3452~104
DOI: 10.25549/usctheses-c3-601275
title: etd-GaddisMala-3657~56
DOI: 10.25549/usctheses-c3-577182
title: etd-CardenasMi-3510_074
DOI: 10.25549/usctheses-c3-589680
title: etd-ChiuCathle-3452~012
DOI: 10.25549/usctheses-c3-599957
title: etd-RuizSusana-3651~114
DOI: 10.25549/usctheses-c3-589670
title: etd-ChiuCathle-3452~002
DOI: 10.25549/usctheses-c3-600000
title: etd-RuizSusana-3651~157
DOI: 10.25549/usctheses-c3-601231
title: etd-GaddisMala-3657~12
DOI: 10.6084/m9.figshare.20551854
title: Meta-Analysis of Pulmonary Artery Denervation for Treatment of Pulmonary Hypertension

description: ABSTRACT Introduction: Pulmonary artery denervation (PADN) can reduce the sympathetic nervous system (SNS) activity, reduce pulmonary artery pressure (PAP), and improve the quality of life in patients with pulmonary hypertension (PH). We conducted a systematic meta-analysis of the effectiveness of PADN in the treatment of PH patients. Methods: This is a comprehensive literature search including all public clinical trials investigating the effects of PADN on PH. Outcomes were mean pulmonary artery pressure (mPAP), pulmonary vascular resistance (PVR), cardiac output (CO), right ventricular (RV) Tei index, 6-minute walk distance (6MWD), and New York Heart Association (NYHA) cardiac function grading. Results: A total of eight clinical studies with 213 PH patients who underwent PADN were included. Meta-analysis showed that after PADN, mPAP (mean difference [MD] -12.51, 95% confidence interval [CI] -17.74 to -7.27, P&lt;0.00001) (mmHg) and PVR (MD -5.17, 95% CI -7.70 to -2.65, P&lt;0.0001) (Wood unit) decreased significantly, CO (MD 0.59, 95% CI 0.32 to 0.86, P&lt;0.0001) (L/min) and 6MWD (MD 107.75, 95% CI 65.64 to 149.86, P&lt;0.00001) (meter) increased significantly, and RV Tei index (MD -0.05, 95% CI -0.28 to 0.17, P=0.63) did not change significantly. Also after PADN, the proportion of NYHA cardiac function grading (risk ratio 0.23, 95% CI 0.14 to 0.37, P&lt;0.00001) III and IV decreased significantly. Conclusion: This meta-analysis supports PADN as a potential new treatment for PH. Further high-quality randomized controlled studies are needed.
DOI: 10.6084/m9.figshare.20551854.v1
title: Meta-Analysis of Pulmonary Artery Denervation for Treatment of Pulmonary Hypertension

description: ABSTRACT Introduction: Pulmonary artery denervation (PADN) can reduce the sympathetic nervous system (SNS) activity, reduce pulmonary artery pressure (PAP), and improve the quality of life in patients with pulmonary hypertension (PH). We conducted a systematic meta-analysis of the effectiveness of PADN in the treatment of PH patients. Methods: This is a comprehensive literature search including all public clinical trials investigating the effects of PADN on PH. Outcomes were mean pulmonary artery pressure (mPAP), pulmonary vascular resistance (PVR), cardiac output (CO), right ventricular (RV) Tei index, 6-minute walk distance (6MWD), and New York Heart Association (NYHA) cardiac function grading. Results: A total of eight clinical studies with 213 PH patients who underwent PADN were included. Meta-analysis showed that after PADN, mPAP (mean difference [MD] -12.51, 95% confidence interval [CI] -17.74 to -7.27, P&lt;0.00001) (mmHg) and PVR (MD -5.17, 95% CI -7.70 to -2.65, P&lt;0.0001) (Wood unit) decreased significantly, CO (MD 0.59, 95% CI 0.32 to 0.86, P&lt;0.0001) (L/min) and 6MWD (MD 107.75, 95% CI 65.64 to 149.86, P&lt;0.00001) (meter) increased significantly, and RV Tei index (MD -0.05, 95% CI -0.28 to 0.17, P=0.63) did not change significantly. Also after PADN, the proportion of NYHA cardiac function grading (risk ratio 0.23, 95% CI 0.14 to 0.37, P&lt;0.00001) III and IV decreased significantly. Conclusion: This meta-analysis supports PADN as a potential new treatment for PH. Further high-quality randomized controlled studies are needed.
DOI: 10.25549/usctheses-c3-599937
title: etd-RuizSusana-3651~094
DOI: 10.25549/usctheses-c3-599889
title: etd-RuizSusana-3651~046
DOI: 10.25549/usctheses-c3-599861
title: etd-RuizSusana-3651~018
DOI: 10.25549/usctheses-c3-589779
title: etd-ChiuCathle-3452~111
DOI: 10.25549/usctheses-c3-577127
title: etd-CardenasMi-3510_019
DOI: 10.25549/usctheses-c3-577129
title: etd-CardenasMi-3510_021
DOI: 10.25549/usctheses-c3-589675
title: etd-ChiuCathle-3452~007
DOI: 10.25549/usctheses-c3-599924
title: etd-RuizSusana-3651~081
DOI: 10.25549/usctheses-c3-599904
title: etd-RuizSusana-3651~061
DOI: 10.25549/usctheses-c3-599880
title: etd-RuizSusana-3651~037
DOI: 10.25549/usctheses-c3-601293
title: etd-GaddisMala-3657~74
DOI: 10.25549/usctheses-c3-601296
title: etd-GaddisMala-3657~77
DOI: 10.25549/usctheses-c3-599853
title: etd-RuizSusana-3651~010
DOI: 10.25549/usctheses-c3-577168
title: etd-CardenasMi-3510_060
DOI: 10.25549/usctheses-c3-601284
title: etd-GaddisMala-3657~65
DOI: 10.25549/usctheses-c3-577109
title: etd-CardenasMi-3510_001
DOI: 10.25549/usctheses-c3-577138
title: etd-CardenasMi-3510_030
DOI: 10.25549/usctheses-c3-599951
title: etd-RuizSusana-3651~108
DOI: 10.25549/usctheses-c3-599917
title: etd-RuizSusana-3651~074
DOI: 10.25549/usctheses-c3-599851
title: etd-RuizSusana-3651~008
DOI: 10.25549/usctheses-c3-601242
title: etd-GaddisMala-3657~23
DOI: 10.25549/usctheses-c3-577179
title: etd-CardenasMi-3510_071
DOI: 10.25549/usctheses-c3-589706
title: etd-ChiuCathle-3452~038
DOI: 10.25549/usctheses-c3-589696
title: etd-ChiuCathle-3452~028
DOI: 10.25549/usctheses-c3-589745
title: etd-ChiuCathle-3452~077
DOI: 10.25549/usctheses-c3-599997
title: etd-RuizSusana-3651~154
DOI: 10.25549/usctheses-c3-601266
title: etd-GaddisMala-3657~47
DOI: 10.25549/usctheses-c3-577122
title: etd-CardenasMi-3510_014
DOI: 10.25549/usctheses-c3-599961
title: etd-RuizSusana-3651~118
DOI: 10.25549/usctheses-c3-589671
title: etd-ChiuCathle-3452~003
DOI: 10.25549/usctheses-c3-589782
title: etd-ChiuCathle-3452~114
DOI: 10.25549/usctheses-c3-577126
title: etd-CardenasMi-3510_018
DOI: 10.25549/usctheses-c3-577216
title: etd-CardenasMi-3510_108
DOI: 10.25549/usctheses-c3-600012
title: etd-RuizSusana-3651~169
DOI: 10.25549/usctheses-c3-577144
title: etd-CardenasMi-3510_036
DOI: 10.25549/usctheses-c3-577176
title: etd-CardenasMi-3510_068
DOI: 10.25549/usctheses-c3-577175
title: etd-CardenasMi-3510_067
DOI: 10.25549/usctheses-c3-599944
title: etd-RuizSusana-3651~101
DOI: 10.6084/m9.figshare.4299203
title: Long noncoding RNA HIT000218960 promotes papillary thyroid cancer oncogenesis and tumor progression by upregulating the expression of high mobility group AT-hook 2 (HMGA2) gene

description: Accumulating evidence suggests that long noncoding RNAs (lncRNAs) play an important role in oncogenesis and tumor progression. However, our knowledge of lncRNAs in thyroid cancer is still limited. To explore the crucial lncRNAs involved in oncogenesis of papillary thyroid cancer (PTC), we acquired data of differentially expressed lncRNAs between PTC tissues and paired adjacent noncancerous thyroid tissues through lncRNA microarray. In the microarray data, we observed that a newly identified lncRNA, HIT000218960, was significantly upregulated in PTC tissues and associated with a well-known oncogene, high mobility group AT-hook 2 (HMGA2) gene. Both in normal thyroid tissues and PTC tissues, the expression of HIT000218960 was significantly positively correlated with that of HMGA2 mRNA. Knockdown of HIT000218960 in PTC cells resulted in downregulation of HMGA2. In addition, functional assays indicated that inhibition of HIT000218960 in PTC cells suppressed cell proliferation, colony formation, migration and invasion in vitro. Increased HIT000218960 expression in PTC tissues was obviously correlated with lymph node metastasis and multifocality, as well as TNM stage. Those findings suggest that HIT000218960 might acts as a tumor promoter through regulating the expression of HMGA2.
DOI: 10.6084/m9.figshare.25195427
title: covid_eco_epi_var

description: The COVID-19 pandemic has caused over 7.02 million deaths as of January 2024 and profoundly affected most countries’ Gross Domestic Product (GDP). Here, we study the interaction of SARS-CoV-2 transmission, mortality, and economic output between January 2020 and December 2022 across 25 European countries.
DOI: 10.25549/usctheses-c3-599912
title: etd-RuizSusana-3651~069
DOI: 10.25549/usctheses-c3-599877
title: etd-RuizSusana-3651~034
DOI: 10.25549/usctheses-c3-601298
title: etd-GaddisMala-3657~79
DOI: 10.25549/usctheses-c3-577208
title: etd-CardenasMi-3510_100
DOI: 10.25549/usctheses-c3-589700
title: etd-ChiuCathle-3452~032
DOI: 10.25549/usctheses-c3-599852
title: etd-RuizSusana-3651~009
DOI: 10.25549/usctheses-c3-599928
title: etd-RuizSusana-3651~085
DOI: 10.25549/usctheses-c3-599927
title: etd-RuizSusana-3651~084
DOI: 10.25549/usctheses-c3-601251
title: etd-GaddisMala-3657~32