cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.26649859
title: Systematic analysis of the adverse effects of commonly used clinical tetracycline drugs based on the FAERS database

description: Tetracyclines are a class of antibacterial drugs commonly used in clinical practice, but there is no systematic analysis of the adverse effects (AEs) of these drugs. We performed such pharmacovigilance analyses using the US Food and Drug Administration Adverse Event Reporting System (FAERS) database to explore tetracycline-related AEs. We used the pharmacovigilance analysis tool Open Vigil 2.1 to access FAERS data and obtained AE reports from January 2004 to June 2023, including doxycycline, minocycline, tigecycline, omadacycline, sarecycline, and eravacycline as the top suspect drugs. The signal value of the AE of the analyzed drug was calculated by the reporting odds ratio (ROR). A total of 15,020 cases were identified by analyzing drugs. In terms of adverse signals, doxycycline caused gastrointestinal mucosal necrosis (ROR = 1699.652); minocycline was reported to cause bone hyperpigmentation (ROR = 30976.223); tigecycline is responsible for blood fibrinogen decreased (ROR = 1714.078). AE reports of tetracycline drugs varied significantly. We found some AEs not mentioned in the instruction, such as the ototoxicity of tetracyclines. Doxycycline was associated with psychiatric side effects; minocycline presented in thyroid and skin tissue-associated tumors; abnormal signals were detected with eravacycline in the blood system.
DOI: 10.6084/m9.figshare.26649859.v1
title: Systematic analysis of the adverse effects of commonly used clinical tetracycline drugs based on the FAERS database

description: Tetracyclines are a class of antibacterial drugs commonly used in clinical practice, but there is no systematic analysis of the adverse effects (AEs) of these drugs. We performed such pharmacovigilance analyses using the US Food and Drug Administration Adverse Event Reporting System (FAERS) database to explore tetracycline-related AEs. We used the pharmacovigilance analysis tool Open Vigil 2.1 to access FAERS data and obtained AE reports from January 2004 to June 2023, including doxycycline, minocycline, tigecycline, omadacycline, sarecycline, and eravacycline as the top suspect drugs. The signal value of the AE of the analyzed drug was calculated by the reporting odds ratio (ROR). A total of 15,020 cases were identified by analyzing drugs. In terms of adverse signals, doxycycline caused gastrointestinal mucosal necrosis (ROR = 1699.652); minocycline was reported to cause bone hyperpigmentation (ROR = 30976.223); tigecycline is responsible for blood fibrinogen decreased (ROR = 1714.078). AE reports of tetracycline drugs varied significantly. We found some AEs not mentioned in the instruction, such as the ototoxicity of tetracyclines. Doxycycline was associated with psychiatric side effects; minocycline presented in thyroid and skin tissue-associated tumors; abnormal signals were detected with eravacycline in the blood system.
DOI: 10.6084/m9.figshare.26317938.v2
title: Comparing musculoskeletal and connective tissue disorder risks of teriparatide and abaloparatide in osteoporosis: an analysis based on FDA adverse event reporting system (FAERS)

description: Osteoporosis (OP), characterized by low bone mass and increased fracture risk, is a prevalent skeletal disorder. Teriparatide (TP) and abaloparatide (ABL) are anabolic agents that may reduce fracture incidence, but their impact on musculoskeletal and connective tissue disorders (MCTD) risk is uncertain A retrospective, observational disproportionality analysis was conducted utilizing FAERS data from Q1 2004 to Q3 2023, where TP or ABL was identified as the primary suspect drug. Multiple data mining algorithms, including reporting odds ratio (ROR), proportional reporting ratio (PRR), Bayesian confidence propagation neural network (BCPNN), and multi-item gamma Poisson shrinker (MGPS), were employed to detect MCTD safety signals. A total of 366,747 TP-related and 422,377 ABL-related cases were identified, predominantly among female patients aged ≥45 years. The top specific AEs involved musculoskeletal, connective tissue, and administration site disorders. Comparative analysis revealed a higher frequency of AEs related to the nervous, cardiovascular, and gastrointestinal systems for ABL compared to TP. Both drugs exhibited strong signals for arthralgia, limb pain, back pain, muscle spasms, bone pain, muscle pain, and muscle weakness The analysis suggests a potential MCTD risk with TP and ABL treatment in OP patients, highlighting the need for AE monitoring and management in clinical practice. This contributes to a better understanding of the safety profiles of these anabolic medications.
DOI: 10.6084/m9.figshare.26405372
title: Post-marketing safety surveillance of fostamatinib: an observational, pharmacovigilance study leveraging FAERS database

description: Fostamatinib, an FDA-approved oral small-molecule spleen tyrosine kinase (SYK) inhibitor, is used to treat thrombocytopenia in adults with chronic immune thrombocytopenia (ITP) who have not responded to previous treatments. However, comprehensive safety data is lacking. This study uses the FDA Adverse Event Reporting System (FAERS) database to explore real-world adverse events (AEs) related to fostamatinib, aiming to inform its clinical use. The FAERS database was retrospectively queried to extract reports associated with fostamatinib from 2019 to 2023. To identify and evaluate potential AEs in patients receiving fostamatinib, various disproportionality analyses such as the reporting odds ratio (ROR), the proportional reporting ratio (PRR), the Bayesian confidence propagation neural network (BCPNN), and the multi-item gamma Poisson shrinker (MGPS) were employed. A total of 23 AE signals were included in our analysis. Among them, hypertension, blood pressure increase, blood pressure abnormality, hepatic enzyme increase, and diarrhea were consistent with the common AEs described for fostamatinib in clinical trials. In addition, unexpected serious AEs were detected including cerebral thrombosis and necrotizing soft tissue infection. The median time to onset of fostamatinib-related AEs was 86 days. Our investigation revealed several possibly emergent safety concerns associated with fostamatinib in real-world clinical practice, which might provide essential vigilance evidence for clinicians and pharmacists to manage the safety issues of fostamatinib.
DOI: 10.6084/m9.figshare.26405372.v1
title: Post-marketing safety surveillance of fostamatinib: an observational, pharmacovigilance study leveraging FAERS database

description: Fostamatinib, an FDA-approved oral small-molecule spleen tyrosine kinase (SYK) inhibitor, is used to treat thrombocytopenia in adults with chronic immune thrombocytopenia (ITP) who have not responded to previous treatments. However, comprehensive safety data is lacking. This study uses the FDA Adverse Event Reporting System (FAERS) database to explore real-world adverse events (AEs) related to fostamatinib, aiming to inform its clinical use. The FAERS database was retrospectively queried to extract reports associated with fostamatinib from 2019 to 2023. To identify and evaluate potential AEs in patients receiving fostamatinib, various disproportionality analyses such as the reporting odds ratio (ROR), the proportional reporting ratio (PRR), the Bayesian confidence propagation neural network (BCPNN), and the multi-item gamma Poisson shrinker (MGPS) were employed. A total of 23 AE signals were included in our analysis. Among them, hypertension, blood pressure increase, blood pressure abnormality, hepatic enzyme increase, and diarrhea were consistent with the common AEs described for fostamatinib in clinical trials. In addition, unexpected serious AEs were detected including cerebral thrombosis and necrotizing soft tissue infection. The median time to onset of fostamatinib-related AEs was 86 days. Our investigation revealed several possibly emergent safety concerns associated with fostamatinib in real-world clinical practice, which might provide essential vigilance evidence for clinicians and pharmacists to manage the safety issues of fostamatinib.
DOI: 10.6084/m9.figshare.26317938.v1
title: Comparing musculoskeletal and connective tissue disorder risks of Teriparatide and abaloparatide in osteoporosis: an analysis based on FDA adverse event reporting system (FAERS)

description: Osteoporosis (OP) is a common skeletal disorder characterized by decreased bone mass and increased fracture risk. Anabolic agents such as teriparatide (TP) and abaloparatide (ABL) have been introduced to stimulate bone formation and reduce fracture incidence. However, whether their use increases the risk of musculoskeletal and connective tissue disorders (MCTD) remains unclear. A retrospective, observational disproportionality analysis was conducted utilizing FAERS data from Q1 2004 to Q3 2023, where TP or ABL was identified as the primary suspect drug. Multiple data mining algorithms, including reporting odds ratio (ROR), proportional reporting ratio (PRR), Bayesian confidence propagation neural network (BCPNN), and multi-item gamma Poisson shrinker (MGPS), were employed to detect MCTD safety signals. A total of 366,747 TP-related and 422,377 ABL-related cases were identified, predominantly among female patients aged ≥45 years. The top specific AEs involved musculoskeletal, connective tissue, and administration site disorders. Comparative analysis revealed a higher frequency of AEs related to the nervous, cardiovascular, and gastrointestinal systems for ABL compared to TP. Both drugs exhibited strong signals for arthralgia, limb pain, back pain, muscle spasms, bone pain, muscle pain, and muscle weakness. This FAERS-based data mining analysis highlighted potential MCTD risk profiles associated with TP and ABL treatment in osteoporosis patients, emphasizing the importance of monitoring and managing these AEs in clinical practice. The findings contribute to a deeper understanding of the safety profiles of these anabolic osteoporosis medications.
DOI: 10.15468/dl.79ztsj
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 "BasisOfRecord is one of (Human Observation, Machine Observation, Occurrence evidence, Observation)",
 "TaxonKey is one of (Dacnis cayana)",
 "Country is one of (American Samoa, Australia, Christmas Island, Cocos (Keeling) Islands, Cook Islands, Fiji, French Polynesia, Guam, Heard Island and McDonald Islands, Kiribati, Marshall Islands, Micronesia (Federated States of), Nauru, New Caledonia, New Zealand, Niue, Norfolk Island, Northern Mariana Islands, Palau, Papua New Guinea, Pitcairn, Samoa, Solomon Islands, Tokelau, Tonga, Tuvalu, United States Minor Outlying Islands, Vanuatu, Wallis and Futuna)"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0024429-250802193616735/datasets/export for details.
DOI: 10.15468/dl.8s9uu5
title: Occurrence Download

description: A dataset containing 2 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Mogera insularis",
 "Country is China",
 "HasCoordinate is true"
 ]
}

 The dataset includes 2 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0024430-250802193616735/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.15098103
title: Synthesis and Radiation Damage of Vacancy-Ordered Double Perovskites, ((NH4)(1-x)FAx)2SnBr6 - Data

description: This Origin file contains the supporting processed data for all of the figures from the main paper from the publication 'Synthesis and Radiation Damage of Vacancy-Ordered Double Perovskites, ((NH4)(1-x)FAx)2SnBr6'.
DOI: 10.5281/zenodo.16759005
title: Synthesis and Radiation Damage of Vacancy-Ordered Double Perovskites, ((NH4)(1-x)FAx)2SnBr6 - Data

description: This Origin file contains the supporting processed data for all of the figures from the main paper from the publication 'Synthesis and Radiation Damage of Vacancy-Ordered Double Perovskites, ((NH4)(1-x)FAx)2SnBr6'.
DOI: 10.15468/dl.e2avxd
title: Occurrence Download

description: A dataset containing 15 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Philippines",
 "TaxonKey is Gardenia pseudopsidium"
 ]
}

 The dataset includes 15 records from 4 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0024431-250802193616735/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.qtxykk
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Chrysolophus pictus",
 "Country is Ecuador",
 "HasCoordinate is true"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0024432-250802193616735/datasets/export for details.
DOI: 10.15468/dl.jyn6ck
title: Occurrence Download

description: A dataset containing 130 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Chrysolophus pictus",
 "Country is Poland",
 "HasCoordinate is true"
 ]
}

 The dataset includes 130 records from 2 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0024433-250802193616735/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.repeap
title: Occurrence Download

description: A dataset containing 222 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Chrysolophus pictus",
 "Country is Sweden",
 "HasCoordinate is true"
 ]
}

 The dataset includes 222 records from 4 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0024434-250802193616735/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.8yah8a
title: Occurrence Download

description: A dataset containing 1240 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Pternistis ahantensis)",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 "License is one of (CC-BY 4.0, CC0 1.0)"
 ]
}

 The dataset includes 1240 records from 18 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0024435-250802193616735/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.21227/mrcp-4075
title: "A Software Architecture Catalog for Fault-Tolerant Containerized Systems"

description: "This paper presents a structured Software Architecture Catalog for Fault-Tolerant Containerized Systems. It addresses the lack of a structured understanding of diverse fault tolerance architectures in containerized environments. The research identifies and systematically validates the presence of five primary fault tolerance tactics in the state of the art: restart, replacement, checkpoint, replication, and migration. These tactics are modeled using BPMN to represent their operational flows. The catalog incorporates an enhanced post-fault diagnostics and offline healing flow to complement online tactics, and offers actionable architectural patterns, providing a consolidated resource for designing more robust containerized applications."
DOI: 10.15468/dl.yav5pe
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Pternistis atrifrons)",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 "License is one of (CC-BY 4.0, CC0 1.0)"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0024436-250802193616735/datasets/export for details.
DOI: 10.6084/m9.figshare.28188245
title: Anonymized Interview Metadata for "Transgressing Beauty and Gender Norms: Textual Analysis of Male Celebgram Posts in Indonesia and Malaysia"

description: This study explores how male beauty influencers in Indonesia and Malaysia are redefining masculinity on Instagram, a platform that offers both opportunity and risk in culturally conservative societies. Through makeup, fashion, and aesthetic expression, these “celebgrams” challenge traditional gender norms while gaining visibility and building supportive online communities. Their presence is partly fueled by a strong female following and the “female gaze,” which helps reshape beauty ideals and opens up professional opportunities. While Instagram offers a relatively safe space for self-expression and empowerment, offline backlash reveals the tension between digital freedom and social conservatism. This research highlights how social media enables layered forms of identity negotiation and cultural change, offering insight into how gender expression is being reimagined in Southeast Asia.<br>
DOI: 10.6084/m9.figshare.28188245.v5
title: Anonymized Interview Metadata for "Transgressing Beauty and Gender Norms: Textual Analysis of Male Celebgram Posts in Indonesia and Malaysia"

description: This study explores how male beauty influencers in Indonesia and Malaysia are redefining masculinity on Instagram, a platform that offers both opportunity and risk in culturally conservative societies. Through makeup, fashion, and aesthetic expression, these “celebgrams” challenge traditional gender norms while gaining visibility and building supportive online communities. Their presence is partly fueled by a strong female following and the “female gaze,” which helps reshape beauty ideals and opens up professional opportunities. While Instagram offers a relatively safe space for self-expression and empowerment, offline backlash reveals the tension between digital freedom and social conservatism. This research highlights how social media enables layered forms of identity negotiation and cultural change, offering insight into how gender expression is being reimagined in Southeast Asia.<br>
DOI: 10.6084/m9.figshare.28188245.v4
title: Anonymized Interview Metadata for "Transgressing Beauty and Gender Norms: Textual Analysis of Male Celebgram Posts in Indonesia and Malaysia"

description: This study examines male Instagram celebrities, termed “celebgrams,” who have emerged as beauty influencers. Historically, beauty has been closely associated with femininity, but male beauty is garnering more attention, especially in Indonesia and Malaysia, where Islamic cultural norms deeply shape societal views on beauty and gender roles. This study explores how six male beauty celebgrams in Indonesia and Malaysia use Instagram to challenge traditional beauty norms and redefine masculinity in conservative societies. Through textual analysis grounded in the framework of transgression within media and cultural studies, this study investigates how these influencers construct alternative narratives and representations of male beauty. The findings reveal that social media platforms, particularly Instagram, empower young men in conservative societies like Indonesia and Malaysia to embrace cosmetics and redefine masculinity. Embracing the concept of the “female gaze,” these influencers challenge societal expectations and push the boundaries of social, cultural, and religious norms. This research underscores the transformative potential of digital spaces as secure environments for self-expression, professional recognition, and community building, reshaping gendered body identities and fostering inclusivity in the discourse on beauty and gender.
DOI: 10.15468/dl.49br5r
title: Occurrence Download

description: A dataset containing 2 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Apistogramma tucurui)",
 "BasisOfRecord is one of (Specimen, Literature Occurrence, Human Observation, Observation)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "Year is greater than or equal to 1991",
 "Year is less than or equal to 2025"
 ]
}

 The dataset includes 2 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0024437-250802193616735/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.745jry
title: Occurrence Download

description: A dataset containing 3911 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Pectinatella magnifica"
 ]
}

 The dataset includes 3911 records from 68 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0024438-250802193616735/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.bayuu4
title: Occurrence Download

description: A dataset containing 271335 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Psophodes olivaceus)",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 "License is one of (CC-BY 4.0, CC0 1.0)"
 ]
}

 The dataset includes 271335 records from 41 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0024410-250802193616735/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.dhetaa
title: Occurrence Download

description: A dataset containing 5 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Randia loheri"
 ]
}

 The dataset includes 5 records from 4 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0024439-250802193616735/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.16758897
title: benchmark
DOI: 10.5281/zenodo.16758898
title: benchmark
DOI: 10.15468/dl.9vshrr
title: Occurrence Download

description: A dataset containing 16687 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Pternistis bicalcaratus)",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 "License is one of (CC-BY 4.0, CC0 1.0)"
 ]
}

 The dataset includes 16687 records from 58 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0024440-250802193616735/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.gjyr22
title: Occurrence Download

description: A dataset containing 20 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Pternistis camerunensis)",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 "License is one of (CC-BY 4.0, CC0 1.0)"
 ]
}

 The dataset includes 20 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0024442-250802193616735/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.zfd7e8
title: Occurrence Download

description: A dataset containing 1662 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Chrysolophus pictus",
 "Country is United Kingdom of Great Britain and Northern Ireland",
 "HasCoordinate is true"
 ]
}

 The dataset includes 1662 records from 33 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0024441-250802193616735/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.