cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.21624517.v1
title: Three Different Strategies for Repair of Symptomatic or Aneurysmatic Aberrant Right Subclavian Arteries

description: ABSTRACT Introduction: In this study, we aimed to present three different methods for symptomatic aberrant right subclavian artery (ARSA) surgery. Methods: We identified 11 consecutive adult patients undergoing symptomatic and/or aneurysmal ARSA repair between January 2016 and December 2020. Symptoms were dysphagia (n=8) and dyspnea + dysphagia (n=3). Six patients had aneurysm formation of the ARSA (mean diameter of 4.2 cm [range 2.8 - 6.3]). All data were analyzed retrospectively. Results: Median age of the patients (7 females/4 males) was 55 years (range 49 - 62). The first four patients (36.4%) underwent hybrid repair using thoracic endovascular aortic repair (TEVAR) and bilateral carotid-subclavian artery bypass (CScBp). Three patients (27.2%) were treated by open ARSA resection/ligation with left mini posterolateral thoracotomy (LMPLT) and right CScBp. And the last four patients (36.4%) underwent ARSA resection/ligation with LMPLT and ascending aorta-right subclavian artery bypass with upper mini sternotomy (UMS). Two of the four patients who underwent TEVAR + bilateral CScBp had continuing dysphagia cause of persistent esophageal compression. Brachial plexus injury developed in one of three patients who underwent LMPLT + right CScBp. Pleural effusion treated with thoracentesis alone was observed in one of four patients who underwent UMS + LMPLT. Conclusion: Among the symptomatic and/or aneurysmal ARSA treatment approaches, surgical and hybrid methods are used. There is still no consensus on how to manage these patients. In our study, we recommend the UMS + LMPLT method, since the risk of complications with anatomical bypass is less, and we have more successful surgical results.
DOI: 10.6084/m9.figshare.21624519
title: Can a pharyngeal bulb prosthesis eliminate hypernasal speech in individuals with hypodynamic velopharynx?

description: ABSTRACT Purpose: to investigate the effectiveness of a pharyngeal bulb prosthesis to eliminate hypernasality in patients with operated cleft palate presenting with diagnosis of hypodynamic velopharynx. Methods: twenty patients with cleft palate, ages 11-40 years, presenting hypodynamic velopharynx participated in the study. Patients had their speech audio recorded twice, with and without prosthesis, simultaneously with nasometry. Three speech-pathologists rated the presence and absence of hypernasality. Perceptual and nasometric data without and with prosthesis were compared, using the McNemar Test (p&lt;0.05). Results: three (15%) patients presented hypernasality without prosthesis and normal resonance with prosthesis, 3 (15%), normal resonance without prosthesis and hypernasality with prosthesis, 9 (45%), hypernasality without and with prosthesis, and 5 (25%), normal resonance in both conditions. Nasometry (≤27% cut off): 1 (5%), presented scores &gt;27% without prosthesis and &lt;27% with prosthesis, 2 (10%), scores &lt;27% without prosthesis and &gt;27% with prosthesis, 17 (85%), scores &gt;27% in both conditions, and 1(5%), scores &lt;27% in both conditions. The comparisons between the results were not significant (p=1.000). Conclusion: the pharyngeal bulb prosthesis alone is insufficient to eliminate hypernasality of patients presented with hypodynamic velopharynx. To this purpose, the combination between the prosthesis and speech therapy is required.
DOI: 10.6084/m9.figshare.21624519.v1
title: Can a pharyngeal bulb prosthesis eliminate hypernasal speech in individuals with hypodynamic velopharynx?

description: ABSTRACT Purpose: to investigate the effectiveness of a pharyngeal bulb prosthesis to eliminate hypernasality in patients with operated cleft palate presenting with diagnosis of hypodynamic velopharynx. Methods: twenty patients with cleft palate, ages 11-40 years, presenting hypodynamic velopharynx participated in the study. Patients had their speech audio recorded twice, with and without prosthesis, simultaneously with nasometry. Three speech-pathologists rated the presence and absence of hypernasality. Perceptual and nasometric data without and with prosthesis were compared, using the McNemar Test (p&lt;0.05). Results: three (15%) patients presented hypernasality without prosthesis and normal resonance with prosthesis, 3 (15%), normal resonance without prosthesis and hypernasality with prosthesis, 9 (45%), hypernasality without and with prosthesis, and 5 (25%), normal resonance in both conditions. Nasometry (≤27% cut off): 1 (5%), presented scores &gt;27% without prosthesis and &lt;27% with prosthesis, 2 (10%), scores &lt;27% without prosthesis and &gt;27% with prosthesis, 17 (85%), scores &gt;27% in both conditions, and 1(5%), scores &lt;27% in both conditions. The comparisons between the results were not significant (p=1.000). Conclusion: the pharyngeal bulb prosthesis alone is insufficient to eliminate hypernasality of patients presented with hypodynamic velopharynx. To this purpose, the combination between the prosthesis and speech therapy is required.
DOI: 10.6084/m9.figshare.21624526
title: JUDGMENT OF JUSTICE OF QUOTAS IN THE UNIVERSITY AND ITS RELATION WITH THE MORAL DEVELOPMENT

description: ABSTRACT The aim of this study is to investigate the relationship between the fairness of quota judgment and the level of moral competency of students and professors. This work was conducted with 317 college students and 15 professors from a base course for engineering at a Public University. We use a structured questionnaire to collect data, composed of a dilemma of quotas and eight arguments related to justice and eight to injustice of quotas. We still apply the Moral Competence Test (MCT_xt), which considers affective and cognitive aspects of the judgment and gives rise to score - C. The results indicated the low C index of the participants, conflict of interest in the judgment of the fairness of quota and the racial issue as the main disagreement factor. Among non-quota students, the higher the C index, the more they considered quotas like unfairness and among quota students, the lower the C score, the greater the choice for fairness. For judgments based on equity, as in the case of affirmative actions, higher levels of moral development would be necessary. Education has an essential role in developing students’ moral competence and, consequently, in promoting their participation in social, civic and professional life.
DOI: 10.6084/m9.figshare.21624526.v1
title: JUDGMENT OF JUSTICE OF QUOTAS IN THE UNIVERSITY AND ITS RELATION WITH THE MORAL DEVELOPMENT

description: ABSTRACT The aim of this study is to investigate the relationship between the fairness of quota judgment and the level of moral competency of students and professors. This work was conducted with 317 college students and 15 professors from a base course for engineering at a Public University. We use a structured questionnaire to collect data, composed of a dilemma of quotas and eight arguments related to justice and eight to injustice of quotas. We still apply the Moral Competence Test (MCT_xt), which considers affective and cognitive aspects of the judgment and gives rise to score - C. The results indicated the low C index of the participants, conflict of interest in the judgment of the fairness of quota and the racial issue as the main disagreement factor. Among non-quota students, the higher the C index, the more they considered quotas like unfairness and among quota students, the lower the C score, the greater the choice for fairness. For judgments based on equity, as in the case of affirmative actions, higher levels of moral development would be necessary. Education has an essential role in developing students’ moral competence and, consequently, in promoting their participation in social, civic and professional life.
DOI: 10.6084/m9.figshare.21624525.v1
title: A MATHEMATICAL MODEL AND SOLUTION METHOD FOR THE BERTH ALLOCATION PROBLEM WITH VARIABLE HANDLING TIME AND CONTINUOUS TIME HORIZON

description: ABSTRACT In this paper, we present the integration of two problems related to the operations in a port terminal: the Berth Allocation Problem (BAP) integrated with the Machine Assignment Problem. We present a mixed-integer linear programming (MILP) formulation, capable of assigning and scheduling incoming vessels to berthing positions and the assignment of machines for handling the vessels. The machines can be quay cranes, mobile cranes, straddle carriers, forklifts, trucks, and any other machine. The problem aims to minimize the waiting time plus the handling time of the vessels. To solve the problem, we developed a heuristic algorithm, capable of solving a problem instance in seconds. To compare the results, we generate several instance problems based on real data and solve them with our MILP formulation implemented in a solver, our heuristic, and a First In First Out (FIFO) algorithm. The solver was able to find solutions only in small-scale instances, and the heuristic was able to find good solutions for all instances.
DOI: 10.6084/m9.figshare.21624525
title: A MATHEMATICAL MODEL AND SOLUTION METHOD FOR THE BERTH ALLOCATION PROBLEM WITH VARIABLE HANDLING TIME AND CONTINUOUS TIME HORIZON

description: ABSTRACT In this paper, we present the integration of two problems related to the operations in a port terminal: the Berth Allocation Problem (BAP) integrated with the Machine Assignment Problem. We present a mixed-integer linear programming (MILP) formulation, capable of assigning and scheduling incoming vessels to berthing positions and the assignment of machines for handling the vessels. The machines can be quay cranes, mobile cranes, straddle carriers, forklifts, trucks, and any other machine. The problem aims to minimize the waiting time plus the handling time of the vessels. To solve the problem, we developed a heuristic algorithm, capable of solving a problem instance in seconds. To compare the results, we generate several instance problems based on real data and solve them with our MILP formulation implemented in a solver, our heuristic, and a First In First Out (FIFO) algorithm. The solver was able to find solutions only in small-scale instances, and the heuristic was able to find good solutions for all instances.
DOI: 10.6084/m9.figshare.21624528
title: IMPROVED BIASED RANDOM KEY GENETIC ALGORITHM FOR THE TWO-DIMENSIONAL NON-GUILLOTINE CUTTING PROBLEM

description: ABSTRACT The two-dimensional cutting problem has a direct relationship with industry problems. There are several proposals to solve these problems. In particular, solution proposals using metaheuristics are the focus of this research. Thus, in this paper, we present a specialized biased random key genetic algorithm. Several tests were performed using known instances in the specific literature, and the results found by the metaheuristics proposed were, in many cases, equal or superior to the results already published in the literature. Another comparison of results presented in this paper is related to the results obtained by specialized metaheuristics and the results found by a mathematical model using commercial software. Once again, in this case, the genetic algorithm presented results equal to or very close to the optimum found by the mathematical model. In addition, the optimization proposal was extended to two-dimensional non-guillotine cutting without parts orientation.
DOI: 10.6084/m9.figshare.21624528.v1
title: IMPROVED BIASED RANDOM KEY GENETIC ALGORITHM FOR THE TWO-DIMENSIONAL NON-GUILLOTINE CUTTING PROBLEM

description: ABSTRACT The two-dimensional cutting problem has a direct relationship with industry problems. There are several proposals to solve these problems. In particular, solution proposals using metaheuristics are the focus of this research. Thus, in this paper, we present a specialized biased random key genetic algorithm. Several tests were performed using known instances in the specific literature, and the results found by the metaheuristics proposed were, in many cases, equal or superior to the results already published in the literature. Another comparison of results presented in this paper is related to the results obtained by specialized metaheuristics and the results found by a mathematical model using commercial software. Once again, in this case, the genetic algorithm presented results equal to or very close to the optimum found by the mathematical model. In addition, the optimization proposal was extended to two-dimensional non-guillotine cutting without parts orientation.
DOI: 10.6084/m9.figshare.21624529
title: ALMOST SQUARING THE SQUARE: OPTIMAL PACKINGS FOR NON-DECOMPOSABLE SQUARES

description: ABSTRACT We consider the problem of finding the minimum uncovered area (trim loss) when tiling non- overlapping distinct integer-sided squares in an N × N square container such that the squares are placed with their edges parallel to those of the container. We find such trim losses and associated optimal packings for all container sizes N from 1 to 101, through an independently developed adaptation of Ian Gambini’s enumerative algorithm. The results were published as a new sequence to The On-Line Encyclopedia of Integer Sequences®. These are the first known results for optimal packings in non-decomposable squares.
DOI: 10.6084/m9.figshare.21624529.v1
title: ALMOST SQUARING THE SQUARE: OPTIMAL PACKINGS FOR NON-DECOMPOSABLE SQUARES

description: ABSTRACT We consider the problem of finding the minimum uncovered area (trim loss) when tiling non- overlapping distinct integer-sided squares in an N × N square container such that the squares are placed with their edges parallel to those of the container. We find such trim losses and associated optimal packings for all container sizes N from 1 to 101, through an independently developed adaptation of Ian Gambini’s enumerative algorithm. The results were published as a new sequence to The On-Line Encyclopedia of Integer Sequences®. These are the first known results for optimal packings in non-decomposable squares.
DOI: 10.6084/m9.figshare.21624532.v1
title: RISK FACTORS IN THE SOFTWARE DEPLOYMENT PHASE: A CASE STUDY APPLIED IN TWO BRAZILIAN GOVERNMENT COMPANIES

description: ABSTRACT This work presents the results of a case study to identify the main risk factors in the software deployment phase involving two government Brazilian companies. The case study was developed through several on-site visits to monitor the deployment of the system adopted by companies and conduct interviews with team managers. The data were acquired mainly through questionnaires applied to the technical team (analysts and developers) involved with the software implementation. After acquiring the data, an empirical analysis was carried out, where the Risk Factors (RF) and the Containment Strategies (CS) identified in the literature were compared with the RF and CS found in the software deployment phase of the two companies. As a result, this work presents 11 risk factors and 14 Containment strategies found in the literature, in addition to a total of 9 RF and 9 CS recorded in the implementation of the software in companies A and B, which had not yet been cataloged in the literature.
DOI: 10.6084/m9.figshare.21624532
title: RISK FACTORS IN THE SOFTWARE DEPLOYMENT PHASE: A CASE STUDY APPLIED IN TWO BRAZILIAN GOVERNMENT COMPANIES

description: ABSTRACT This work presents the results of a case study to identify the main risk factors in the software deployment phase involving two government Brazilian companies. The case study was developed through several on-site visits to monitor the deployment of the system adopted by companies and conduct interviews with team managers. The data were acquired mainly through questionnaires applied to the technical team (analysts and developers) involved with the software implementation. After acquiring the data, an empirical analysis was carried out, where the Risk Factors (RF) and the Containment Strategies (CS) identified in the literature were compared with the RF and CS found in the software deployment phase of the two companies. As a result, this work presents 11 risk factors and 14 Containment strategies found in the literature, in addition to a total of 9 RF and 9 CS recorded in the implementation of the software in companies A and B, which had not yet been cataloged in the literature.
DOI: 10.6084/m9.figshare.21624534
title: Pharmaceutical evaluation of compounded furosemide capsules and excipient performance

description: Abstract Compounding pharmacies play an important role not only in compounding personalized formulations, but also preparing drugs at the same concentration and dosage as those from commercial manufacturers. The excipients used in compounding are generally standardized for many drugs, however they do not consider the intrinsic properties, such as the poor water solubility, of each substance. The excipient performance of commercially available compounded furosemide capsules in 7 compounding pharmacies from Manaus was evaluated and compared them to the performance of the reference medicinal product (Lasix® tablets) and 2 batches of capsules made in-house (T2 and T4) with a standardized excipient. All batches were subjected to tests for weight variation, assay, uniformity of dosage units, disintegration and dissolution profile. Of the 7 different compound formulas acquired in the compounding pharmacies, only 2 passed all tests. Most formulas passed the tests for weight determination, disintegration time and assay, however batches from 2 establishments failed in regards to the uniformity of the content and 5 batches failed the dissolution test. The reference medicinal product was approved in all tests, as were the T2 capsules made in-house with drug-excipient ratio 1:2. These results confirm the importance of the excipient composition, especially for poorly soluble drugs.
DOI: 10.6084/m9.figshare.21624534.v1
title: Pharmaceutical evaluation of compounded furosemide capsules and excipient performance

description: Abstract Compounding pharmacies play an important role not only in compounding personalized formulations, but also preparing drugs at the same concentration and dosage as those from commercial manufacturers. The excipients used in compounding are generally standardized for many drugs, however they do not consider the intrinsic properties, such as the poor water solubility, of each substance. The excipient performance of commercially available compounded furosemide capsules in 7 compounding pharmacies from Manaus was evaluated and compared them to the performance of the reference medicinal product (Lasix® tablets) and 2 batches of capsules made in-house (T2 and T4) with a standardized excipient. All batches were subjected to tests for weight variation, assay, uniformity of dosage units, disintegration and dissolution profile. Of the 7 different compound formulas acquired in the compounding pharmacies, only 2 passed all tests. Most formulas passed the tests for weight determination, disintegration time and assay, however batches from 2 establishments failed in regards to the uniformity of the content and 5 batches failed the dissolution test. The reference medicinal product was approved in all tests, as were the T2 capsules made in-house with drug-excipient ratio 1:2. These results confirm the importance of the excipient composition, especially for poorly soluble drugs.
DOI: 10.6084/m9.figshare.21624537
title: Nasal airflow measures and peak inspiratory flow in mouth-breathing children before and after nasal cleansing and massage maneuvers

description: ABSTRACT This study aimed at investigating the effects of nasal cleansing and massage maneuvers on upper airway patency in mouth-breathing children. This is a case report on eight children, aged 7 to 10 years, with a speech-language-hearing diagnosis of mouth breathing and otorhinolaryngological assessment and clinical diagnosis of rhinitis. Nasal airflow and patency were respectively assessed with the Glatzel mirror and Peak Nasal Inspiratory Flow (PNIF). Then, they were submitted to nasal cleansing and massage maneuvers with a saline solution, followed by reassessment with the Glatzel mirror and PNIF to compare results. The medians of total nasal airflow quantification were significant. Data on unilateral nasal cavity measurement indicated a sharp increase in nasal airflow in each nostril, with statistically significant differences between before and after nasal cleansing and massage maneuvers. The medians of the total PNIF were significant after the cleansing. It is concluded that the nasal airflow increased in PNIF after the cleansing maneuver.
DOI: 10.6084/m9.figshare.21624537.v1
title: Nasal airflow measures and peak inspiratory flow in mouth-breathing children before and after nasal cleansing and massage maneuvers

description: ABSTRACT This study aimed at investigating the effects of nasal cleansing and massage maneuvers on upper airway patency in mouth-breathing children. This is a case report on eight children, aged 7 to 10 years, with a speech-language-hearing diagnosis of mouth breathing and otorhinolaryngological assessment and clinical diagnosis of rhinitis. Nasal airflow and patency were respectively assessed with the Glatzel mirror and Peak Nasal Inspiratory Flow (PNIF). Then, they were submitted to nasal cleansing and massage maneuvers with a saline solution, followed by reassessment with the Glatzel mirror and PNIF to compare results. The medians of total nasal airflow quantification were significant. Data on unilateral nasal cavity measurement indicated a sharp increase in nasal airflow in each nostril, with statistically significant differences between before and after nasal cleansing and massage maneuvers. The medians of the total PNIF were significant after the cleansing. It is concluded that the nasal airflow increased in PNIF after the cleansing maneuver.
DOI: 10.6084/m9.figshare.21624538
title: Environmental Fragility in a Permanent Preservation Area

description: Abstract Permanent preservation areas reduce the exposure of sediments and nutrients in aquatic medium and improve the quality of water. The analysis of natural features and anthropic use in rivers’ surroundings makes it possible detecting potential ecological unbalance. This study analyzed the potential and emerging environmental fragility in Permanent Preservation Areas (PPA). Environmental fragilities around drainage areas composing the sub-basin were assessed based on soil, relief, rainfall, land use/land cover (LULC) features. The degrees of emerging environmental fragility observed in the second-order stream were lower than those in first-order ones: 3.07 and 2.68, on average, respectively; and standard deviation of approximately 0.7 was recorded in each group. First-order streams are more closely associated with high slopes, and it increases their fragility. Then reduction of fragility levels around water springs due to conservationist practices will decrease material and energy transfer throughout network connections and rebalance the assessed aquatic ecosystem.