cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.5666407
title: Using Respondent Driven Sampling for assessing alcoholism in women

description: ABSTRACT In this cross-sectional observational study, our focus is to show statistics related to women who use excessive alcohol. Howewer, the difficulty to obtain a frame to consider a sampling design of alcoholic women, it was decided as an alternative the use of the Respondent Driven Sampling (RDS) method. The method allowed the presentation of indicators related to alcoholism based on a sample of 36 women selected from treatment centers. The results of the survey showed that of 91.7% of women who make excessive use of alcohol in combination with other drugs, 69.44% use marijuana and cigarettes. And, of the 30,087 women who consume alcohol, 24,371 need evaluation and treatment.
DOI: 10.6084/m9.figshare.5666407.v1
title: Using Respondent Driven Sampling for assessing alcoholism in women

description: ABSTRACT In this cross-sectional observational study, our focus is to show statistics related to women who use excessive alcohol. Howewer, the difficulty to obtain a frame to consider a sampling design of alcoholic women, it was decided as an alternative the use of the Respondent Driven Sampling (RDS) method. The method allowed the presentation of indicators related to alcoholism based on a sample of 36 women selected from treatment centers. The results of the survey showed that of 91.7% of women who make excessive use of alcohol in combination with other drugs, 69.44% use marijuana and cigarettes. And, of the 30,087 women who consume alcohol, 24,371 need evaluation and treatment.
DOI: 10.6084/m9.figshare.5666404
title: Application of Friction Surfacing to the Production of Aluminum Coatings Reinforced with Al2O3 Particles

description: The aim of this work was to produce deposits of AA6351-T6, reinforced with alumina (Al2O3) particles, over a substrate of AA5052-H32 through friction surfacing. AA6351-T6 consumable rods were drilled with one and two holes, which were filled with Al2O3 particles posteriorly. To perform the deposition, a conventional KONE KFE-3/BR milling machine was used. The results showed that Al2O3 particles increase the hardness values of the produced deposits when compared to those without particle addition. The coatings presented a fine equiaxed grain size distribution, once the grain refinement was nearly 48% lower than the as-received material. Moreover, deposit regions that showed finer grain boundaries also showed a higher volume fraction, which can be related to the particle stimulated phenomenon. Electron backscatter diffraction results showed the occurrence of low angle grain boundary substructures and lattice rotation, indicating that the material undergoes dynamic recrystallization during friction surfacing.
DOI: 10.6084/m9.figshare.5666395
title: Effect of Milk Renewal on Cell Viability In Vitro at Different Time Frames

description: Abstract The purpose of this study was to evaluate if the renewal of milk as a storage medium, every 12, 24 and 48 h, is able to increase its ability to maintain human periodontal ligament fibroblasts (PDLF) viability over time. PDLF were soaked in Minimum Essential Medium at 37 °C (MEM-37) (positive control), tap water (Water) (negative control) and in skimmed milk (44 wells) at 5 °C and 20 °C. The skimmed milk was renewed every 12 h (Milk-12), 24 h (Milk-24) and 48 h (Milk-48) in 11 wells of each plate, and the milk in the remaining 11 wells of each plate was maintained in situ (not renewed milk) (NRM). After 24, 48, 72, 96 and 120 h, cell viability was determined by the tetrazolium salt-based colorimetric (MTT) assay. Data were statistically analyzed by Kruskal-Wallis, Scheffé and Mann-Whitney tests (a=5%). At 5 °C, only Milk-48 was significantly better than NRM. At 20 °C, NRM was more effective than Milk-12 and Milk-24 in all time periods. In relation to the temperature (5 °C or 20 °C), renewal of milk at 5 °C was better in maintaining cell viability than the renewal at 20 °C. In conclusion, the renewal of milk was able to increase its ability to maintain cell viability only when performed every 48 h in milk maintained at 5 °C.
DOI: 10.6084/m9.figshare.5666395.v1
title: Effect of Milk Renewal on Cell Viability In Vitro at Different Time Frames

description: Abstract The purpose of this study was to evaluate if the renewal of milk as a storage medium, every 12, 24 and 48 h, is able to increase its ability to maintain human periodontal ligament fibroblasts (PDLF) viability over time. PDLF were soaked in Minimum Essential Medium at 37 °C (MEM-37) (positive control), tap water (Water) (negative control) and in skimmed milk (44 wells) at 5 °C and 20 °C. The skimmed milk was renewed every 12 h (Milk-12), 24 h (Milk-24) and 48 h (Milk-48) in 11 wells of each plate, and the milk in the remaining 11 wells of each plate was maintained in situ (not renewed milk) (NRM). After 24, 48, 72, 96 and 120 h, cell viability was determined by the tetrazolium salt-based colorimetric (MTT) assay. Data were statistically analyzed by Kruskal-Wallis, Scheffé and Mann-Whitney tests (a=5%). At 5 °C, only Milk-48 was significantly better than NRM. At 20 °C, NRM was more effective than Milk-12 and Milk-24 in all time periods. In relation to the temperature (5 °C or 20 °C), renewal of milk at 5 °C was better in maintaining cell viability than the renewal at 20 °C. In conclusion, the renewal of milk was able to increase its ability to maintain cell viability only when performed every 48 h in milk maintained at 5 °C.
DOI: 10.6084/m9.figshare.5666392
title: Biomechanical study of the effect of platelet rich plasma on the treatment of medial collateral ligament lesion in rabbits

description: Abstract Purpose: To evaluate the use of platelet-rich plasma in the early stages of healing of traumatic injury of the medial collateral ligament in the knee of rabbits. Methods: Thirty rabbits were subjected to surgical lesion of the medial collateral ligament. Of these, 16 were treated with platelet-rich plasma and 14 with saline (control). After 3 and 6 weeks of treatment, 50% of the animals from each group were sacrificed, and biomechanical tests were performed on the injured ligament to compare the tensile strength between the two groups. Results: Platelet-rich plasma significantly increased the tensile strength of the ligament in the groups treated after3 and 6 weeks. In the group treated with platelet-rich plasma vs. saline, the tensile strength values were 3192.5 ± 189.7 g/f vs. 2851.1 ± 193.1 g/f at3 weeks (p = 0.005) and 5915.6 ± 832.0 g/f vs. 4187.6 ± 512.9 g/f at 6 weeks (p = 0.0001). Conclusion: The use of platelet-rich plasma at the injury site accelerated ligament healing in an animal model, demonstrated by an increase in the tensile strength of the medial collateral ligament.
DOI: 10.6084/m9.figshare.5666392.v1
title: Biomechanical study of the effect of platelet rich plasma on the treatment of medial collateral ligament lesion in rabbits

description: Abstract Purpose: To evaluate the use of platelet-rich plasma in the early stages of healing of traumatic injury of the medial collateral ligament in the knee of rabbits. Methods: Thirty rabbits were subjected to surgical lesion of the medial collateral ligament. Of these, 16 were treated with platelet-rich plasma and 14 with saline (control). After 3 and 6 weeks of treatment, 50% of the animals from each group were sacrificed, and biomechanical tests were performed on the injured ligament to compare the tensile strength between the two groups. Results: Platelet-rich plasma significantly increased the tensile strength of the ligament in the groups treated after3 and 6 weeks. In the group treated with platelet-rich plasma vs. saline, the tensile strength values were 3192.5 ± 189.7 g/f vs. 2851.1 ± 193.1 g/f at3 weeks (p = 0.005) and 5915.6 ± 832.0 g/f vs. 4187.6 ± 512.9 g/f at 6 weeks (p = 0.0001). Conclusion: The use of platelet-rich plasma at the injury site accelerated ligament healing in an animal model, demonstrated by an increase in the tensile strength of the medial collateral ligament.
DOI: 10.6084/m9.figshare.5666389
title: Incremental Prognostic Value of the Incorporation of Clinical Data Into Coronary Anatomy Data in Acute Coronary Syndromes: SYNTAX-GRACE Score

description: Abstract Background: When performing coronary angiography in patients with acute coronary syndrome (ACS), the anatomical extent of coronary disease usually prevails in the prognostic reasoning. It has not yet been proven if clinical data should be accounted for in risk stratification together with anatomical data. Objective: To test the hypothesis that clinical data increment the prognostic value of anatomical data in patients with ACS. Methods: Patients admitted with objective criteria for ACS and who underwent angiography during hospitalization were included. Primary outcome was defined as in-hospital cardiovascular death, and the prognostic value of the SYNTAX Score (anatomical data) was compared to that of the SYNTAX-GRACE Score, which resulted from the incorporation of the GRACE Score into the SYNTAX score. The Integrated Discrimination Improvement (IDI) was calculated to evaluate the SYNTAX-GRACE Score ability to correctly reclassify information from the traditional SYNTAX model. Results: This study assessed 365 patients (mean age, 64 ± 14 years; 58% male). In-hospital cardiovascular mortality was 4.4%, and the SYNTAX Score was a predictor of that outcome with a C-statistic of 0.81 (95% CI: 0.70 - 0.92; p &lt; 0.001). The GRACE Score was a predictor of in-hospital cardiac death independently of the SYNTAX Score (p &lt; 0.001, logistic regression). After incorporation into the predictive model, the GRACE Score increased the discrimination capacity of the SYNTAX Score from 0.81 to 0.92 (95% CI: 0.87 - 0.96; p = 0.04). Conclusion: In patients with ACS, clinical data complement the prognostic value of coronary anatomy. Risk stratification should be based on the clinical-anatomical paradigm, rather than on angiographic data only.
DOI: 10.6084/m9.figshare.5666389.v1
title: Incremental Prognostic Value of the Incorporation of Clinical Data Into Coronary Anatomy Data in Acute Coronary Syndromes: SYNTAX-GRACE Score

description: Abstract Background: When performing coronary angiography in patients with acute coronary syndrome (ACS), the anatomical extent of coronary disease usually prevails in the prognostic reasoning. It has not yet been proven if clinical data should be accounted for in risk stratification together with anatomical data. Objective: To test the hypothesis that clinical data increment the prognostic value of anatomical data in patients with ACS. Methods: Patients admitted with objective criteria for ACS and who underwent angiography during hospitalization were included. Primary outcome was defined as in-hospital cardiovascular death, and the prognostic value of the SYNTAX Score (anatomical data) was compared to that of the SYNTAX-GRACE Score, which resulted from the incorporation of the GRACE Score into the SYNTAX score. The Integrated Discrimination Improvement (IDI) was calculated to evaluate the SYNTAX-GRACE Score ability to correctly reclassify information from the traditional SYNTAX model. Results: This study assessed 365 patients (mean age, 64 ± 14 years; 58% male). In-hospital cardiovascular mortality was 4.4%, and the SYNTAX Score was a predictor of that outcome with a C-statistic of 0.81 (95% CI: 0.70 - 0.92; p &lt; 0.001). The GRACE Score was a predictor of in-hospital cardiac death independently of the SYNTAX Score (p &lt; 0.001, logistic regression). After incorporation into the predictive model, the GRACE Score increased the discrimination capacity of the SYNTAX Score from 0.81 to 0.92 (95% CI: 0.87 - 0.96; p = 0.04). Conclusion: In patients with ACS, clinical data complement the prognostic value of coronary anatomy. Risk stratification should be based on the clinical-anatomical paradigm, rather than on angiographic data only.
DOI: 10.6084/m9.figshare.5666386
title: Left Atrial Appendage Closure with Amplatzer Cardiac Plug in Nonvalvular Atrial Fibrillation: Safety and Long-Term Outcome

description: Abstract Background: Atrial fibrillation (AF) is a cardiac arrhythmia with high risk for thromboembolic events, specially stroke. Objective: To assess the safety of left atrial appendage closure (LAAC) with the Amplatzer Cardiac Plug for the prevention of thromboembolic events in patients with nonvalvular AF. Methods: This study included 15 patients with nonvalvular AF referred for LAAC, 6 older than 75 years (mean age, 69.4 ± 9.3 years; 60% of the male sex). Results: The mean CHADS2 score was 3.4 ± 0.1, and mean CHA2DS2VASc , 4.8 ± 1.8, evidencing a high risk for thromboembolic events. All patients had a HAS-BLED score &gt; 3 (mean, 4.5 ± 1.2) with a high risk for major bleeding within 1 year. The device was successfully implanted in all patients, with correct positioning in the first attempt in most of them (n = 11; 73.3%). Conclusion: There was no periprocedural complication, such as device migration, pericardial tamponade, vascular complications and major bleeding. All patients had an uneventful in-hospital course, being discharged in 2 days. The echocardiographic assessments at 6 and 12 months showed neither device migration, nor thrombus formation, nor peridevice leak. On clinical assessment at 12 months, no patient had thromboembolic events or bleeding related to the device or risk factors. In this small series, LAAC with Amplatzer Cardiac Plug proved to be safe, with high procedural success rate and favorable outcome at the 12-month follow-up. (Arq Bras Cardiol. 2017; [online].ahead print, PP.0-0)
DOI: 10.6084/m9.figshare.5666386.v1
title: Left Atrial Appendage Closure with Amplatzer Cardiac Plug in Nonvalvular Atrial Fibrillation: Safety and Long-Term Outcome

description: Abstract Background: Atrial fibrillation (AF) is a cardiac arrhythmia with high risk for thromboembolic events, specially stroke. Objective: To assess the safety of left atrial appendage closure (LAAC) with the Amplatzer Cardiac Plug for the prevention of thromboembolic events in patients with nonvalvular AF. Methods: This study included 15 patients with nonvalvular AF referred for LAAC, 6 older than 75 years (mean age, 69.4 ± 9.3 years; 60% of the male sex). Results: The mean CHADS2 score was 3.4 ± 0.1, and mean CHA2DS2VASc , 4.8 ± 1.8, evidencing a high risk for thromboembolic events. All patients had a HAS-BLED score &gt; 3 (mean, 4.5 ± 1.2) with a high risk for major bleeding within 1 year. The device was successfully implanted in all patients, with correct positioning in the first attempt in most of them (n = 11; 73.3%). Conclusion: There was no periprocedural complication, such as device migration, pericardial tamponade, vascular complications and major bleeding. All patients had an uneventful in-hospital course, being discharged in 2 days. The echocardiographic assessments at 6 and 12 months showed neither device migration, nor thrombus formation, nor peridevice leak. On clinical assessment at 12 months, no patient had thromboembolic events or bleeding related to the device or risk factors. In this small series, LAAC with Amplatzer Cardiac Plug proved to be safe, with high procedural success rate and favorable outcome at the 12-month follow-up. (Arq Bras Cardiol. 2017; [online].ahead print, PP.0-0)
DOI: 10.6084/m9.figshare.5666383
title: SITE CLASSIFICATION FOR EUCALYPT STANDS USING ARTIFICIAL NEURAL NETWORK BASED ON ENVIRONMENTAL AND MANAGEMENT FEATURES

description: ABSTRACT Several methods have been proposed to perform site classification for timber production. However, there is frequent need to assess site productive capacity before forest establishment. This has motivated the application of Artificial Neural Networks (ANN) for site classification. Hereby, the traditional guide curve (GC) procedure was compared to the ANN with no stand measures as input. In addition, different ANN settings were tested to assess the best setting. The variables used to train the ANN were: climatic variables, soil types, spacing and genetic material. The results from the ANN and the GC methods were compared to the observed classes, which were defined using the observed dominant high at the age of seven years. The comparison was performed using the Kappa coefficient (K) and descriptive analysis. The results showed that the cost function “Cross Entropy” and the output activation function “Softmax” were the best for this purpose. The ANN classification resulted in substantial agreement with the observed indices against a moderate agreement of the GC procedure. The change in growth patterns throughout the rotation may have hindered the proper classification by the CG method, which does not happen with the ANN. Moreover, the GC method shows efficiency on classification in cases which data from stands at the age close to the reference age are available. Also, it could be possible to improve its accuracy if another advanced regression techniques were applied. However, the ANN method presented here is not sensible to growth instability and allows classifying sites with no plantation history.
DOI: 10.6084/m9.figshare.5666383.v1
title: SITE CLASSIFICATION FOR EUCALYPT STANDS USING ARTIFICIAL NEURAL NETWORK BASED ON ENVIRONMENTAL AND MANAGEMENT FEATURES

description: ABSTRACT Several methods have been proposed to perform site classification for timber production. However, there is frequent need to assess site productive capacity before forest establishment. This has motivated the application of Artificial Neural Networks (ANN) for site classification. Hereby, the traditional guide curve (GC) procedure was compared to the ANN with no stand measures as input. In addition, different ANN settings were tested to assess the best setting. The variables used to train the ANN were: climatic variables, soil types, spacing and genetic material. The results from the ANN and the GC methods were compared to the observed classes, which were defined using the observed dominant high at the age of seven years. The comparison was performed using the Kappa coefficient (K) and descriptive analysis. The results showed that the cost function “Cross Entropy” and the output activation function “Softmax” were the best for this purpose. The ANN classification resulted in substantial agreement with the observed indices against a moderate agreement of the GC procedure. The change in growth patterns throughout the rotation may have hindered the proper classification by the CG method, which does not happen with the ANN. Moreover, the GC method shows efficiency on classification in cases which data from stands at the age close to the reference age are available. Also, it could be possible to improve its accuracy if another advanced regression techniques were applied. However, the ANN method presented here is not sensible to growth instability and allows classifying sites with no plantation history.
DOI: 10.6084/m9.figshare.5666380
title: SPIROMETRY IN SCHOOLCHILDREN FOR FIELD STUDIES: DOES TESTING ON DIFFERENT DAYS CHANGE THE RESULT OF THE EXAM?

description: ABSTRACT Objective: To analyze if there is variation in the results of spirometry performed by healthy schoolchildren on different days. Methods: Cross-sectional study with healthy schoolchildren aged 7 to 12 years old, in Florianópolis, Santa Catarina, Southern Brazil. Prepubescent children, non-athletes, born at full term, without cardiorespiratory, rheumatic, musculoskeletal, neurological and visual or hearing deficit were included. The child’s health was assessed by a health questionnaire and by the survey International Study of Asthma and Allergies in Childhood. The spirometric test was performed on 3 different days, not exceeding the interval of 15 days between the first and last exams, following the guidelines of the American Thoracic Society. The absolute values and percentages of predicted values of forced vital capacity, forced volume in the first second and peak expiratory flow were analyzed. Statistical analysis was performed using the Shapiro-Wilk normality test followed by one-way analysis of variance or Friedman test and by Bonferroni’s post-hoc test for multiple parametric comparisons. Also, the intraclass correlation coefficient was applied to compare results on the same patients on the different tested days. Results: Twenty-two children were analyzed, with a mean age of 9.3±1.1 years. All the spirometric parameters showed a reduction in absolute value after the first exam, but without significant difference. Regarding reproducibility of spirometry results, the tests presented intraclass correlation coefficient &gt;0.70. Conclusions: There was no change in the results of spirometry performed by healthy schoolchildren on three different days.
DOI: 10.6084/m9.figshare.5666380.v1
title: SPIROMETRY IN SCHOOLCHILDREN FOR FIELD STUDIES: DOES TESTING ON DIFFERENT DAYS CHANGE THE RESULT OF THE EXAM?

description: ABSTRACT Objective: To analyze if there is variation in the results of spirometry performed by healthy schoolchildren on different days. Methods: Cross-sectional study with healthy schoolchildren aged 7 to 12 years old, in Florianópolis, Santa Catarina, Southern Brazil. Prepubescent children, non-athletes, born at full term, without cardiorespiratory, rheumatic, musculoskeletal, neurological and visual or hearing deficit were included. The child’s health was assessed by a health questionnaire and by the survey International Study of Asthma and Allergies in Childhood. The spirometric test was performed on 3 different days, not exceeding the interval of 15 days between the first and last exams, following the guidelines of the American Thoracic Society. The absolute values and percentages of predicted values of forced vital capacity, forced volume in the first second and peak expiratory flow were analyzed. Statistical analysis was performed using the Shapiro-Wilk normality test followed by one-way analysis of variance or Friedman test and by Bonferroni’s post-hoc test for multiple parametric comparisons. Also, the intraclass correlation coefficient was applied to compare results on the same patients on the different tested days. Results: Twenty-two children were analyzed, with a mean age of 9.3±1.1 years. All the spirometric parameters showed a reduction in absolute value after the first exam, but without significant difference. Regarding reproducibility of spirometry results, the tests presented intraclass correlation coefficient &gt;0.70. Conclusions: There was no change in the results of spirometry performed by healthy schoolchildren on three different days.
DOI: 10.6084/m9.figshare.5666377
title: Family caregivers articulating the social network of a child with special health care needs

description: ABSTRACT In Brazil, studies rarely address the social network of a child with special health care needs (CSHCN). Objective: the study sought to characterize the social network of the child and analyze the role of the family in its creation. Method: a qualitative approach was developed through five dynamics (Speaking Map) based on the creative sensitive method, with five groups of families (12 participants) in their homes. Results: the critical discourse analysis of the caregivers (grandparents, siblings and neighbors) showed that the mother plays the main role in articulating the social network, with its points being linked by the hospital, primary and rehabilitation care, household, school, etc. Familial care becomes more visible at home and within the community. Conclusion: with the insufficient public policy that articulating healthcare facilities for CSHCN in the community, family members shape a social network characterized by a dense and fluid mesh.