cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.15151/esrf-es-948303735
title: Molecular structural basis of the effect of external load on the mechanical performance of skeletal muscle

description: This proposal will use time-resolved X-ray diffraction to determine the contribution of novel regulatory mechanisms in the myosin-containing thick filaments in fast-twitch skeletal muscles of mammals to the performance of those muscles in response to changes in external load. The protocols will mimic the normal functions of human skeletal muscles in everyday life, providing the fundamental mechanistic understanding to underpin the development of novel therapies for muscle weakness. The ID02 beamline with Eiger 2-4M detector is uniquely suitable worldwide to determine the relevant molecular structural changes in isolated muscle.
DOI: 10.6084/m9.figshare.21213257.v1
title: Preventive and healing effect of high dosing grape seed flour on CKD patients of various stages and aetiologies

description: Chronic kidney disease (CKD) is a worldwide public health concern characterised by a progressive alteration of renal function, and obesity, diabetes and hypertension are major risk factors. Oxidative stress is commonly observed in CKD patients resulting from an imbalance between overproduction of reactive oxygen species (ROS) and impairment of defense mechanisms. Therefore, strategies that alleviate oxidative stress may have major clinical implications towards improving vascular health and reducing the burden of CKD. Also, CKD worsens the quality of life of patients, therefore it is fundamental to implement new therapeutic strategies aimed at slowing down its progression. This interventional study is a randomised placebo-controlled clinical trial consisting at the daily oral supplementation with high dosing grape seed flour (GSF ≈ 1 g/kg) for experimental (n = 30) or starch for placebo (n = 10) to patients suffering from CKD of various stages and aetiologies. Blood and urine samples were collected at baseline and after a six-month-long supplementation period to follow up the disease evolution through the determination of renal function biomarkers, as well as antioxidant, anti-inflammatory and blood parameters. Supplementation with high dosing GSF was safe and well tolerated during the entire period of investigation. GSF clearly improved the main renal function biomarkers as GFR, proteinuria, blood pressure, oxidative stress and inflammation as well as the overall patient welfare as indicated by several blood parameters. Most importantly high dosing GSF specifically halted and even reversed the progression of diabetic nephropathy a major cause of CKD and end stage renal disease.
DOI: 10.15151/esrf-es-947339285
title: operando synchrotron X-ray diffraction and pair distribution function analysis: understanding lithiation/delithiation mechanism in graphite-

description: In this proposal, we aim to gain insights into lithium distribution and lithiation/delithiation mechanism of graphite-silicon (Gr-Si) composite anode using combined techniques of high-energy operando synchrotron X-ray diffraction and total X-ray scattering analyzed by pair distribution function. We aim to probe the degradation mechanism of Gr-Si anode cycled at different C-rates in long- and short-structure ranges. The proposed experiments are under the umbrella of the Big-Map and BATTERY 2030+ projects.
DOI: 10.15151/esrf-es-947339466
title: Localization of fibrillar polymorphs in human brain tissue

description: Fibrillar aggregates of Abeta peptides and tau protein are defining features of Alzheimer's disease (AD) but the role these structures play in the etiology of disease remains uncertain. Outstanding questions remain as to the distribution of polymorphs between and within cases. The proposed work will apply x-ray scanning micro- and nano-diffraction to histological sections of human brain tissue in order to map the distribution and arrangement of fibrillar aggregates of these proteins in plaques and tangles. The central hypothesis of the proposed work is that the spatial distribution of structural polymorphs in brain tissue will provide important clues as to how fibrils contribute to disease. The results of these studies will provide a preliminary assessment of whether or not different fibrillar polymorphs spread by a prion-like process during disease progression and provide insights into the mechanisms by which different strains are associated with different disease subtypes.
DOI: 10.15151/esrf-es-947339778
title: Light-induced halide ion segregation in hybride perovskites

description: We will use X-ray photon correlation spectroscopy to reveal the reversible dynamics of the light-soaking domains in hybrid organic-inorganic perovskites. These domains appear due to light-induced segregation of iodide and bromide ions in MAPb(I/Br)3 films and are characterized by different band gaps and slightly different crystal structures. Using the scattering of coherent X-rays in Bragg geometry, we will characterize the size of the iodine-rich and bromide-rich domains and obtain a characteristic time scale of their formation. This information will help to improve the stability of the perovskite-based solar cells. These kind of experiment can be applicable rather generally to study the ion migration in various soft- and hard-condensed matter systems.
DOI: 10.15151/esrf-es-947341209
title: Study How Intracrystalline Amino Acids Tune the Magnetization of Manganese (II) Carbonate

description: Incorporation of organic molecules into the lattice of inorganic crystalline hosts is a common phenomenon in biomineralization, and has been shown to alter various properties of the crystalline host. Taking this phenomenon as our source of inspiration, we propose herein to study how incorporation of specific single amino acids into the lattice of manganese (II) carbonate alters its inherent magnetic properties. Our preliminary results show that amino-acid-incorporating paramagnetic MnCO3 exhibits different magnetic behavior as compared to that of pure MnCO3. We will study the effect the incorporation of amino acids have on the lattice distortion and microstructure of the host crystal and correlate this to the measured magnetic properties. We will also study the changes in structure below the Néel temperature at 5K as well as perform in-situ heating to study the kinetics of the lattice distortion relaxation and correlate this as well to the magnetic properties.
DOI: 10.15151/esrf-es-946447414
title: Time- and space- resolved SAXS investigation of the effect of Mg on the precipitation of Al3(Sc,Zr).

description: This experiment consists in a time- and space- resolved SAXS study of the effect of Mg concentration on the precipitation of nano scale Al3 (Sc,Zr) precipitates with a core-shell structure. To investigate the impact of Mg, samples containing an Mg concentration gradient will be used and probed at different locations of the gradient. The SAXS study will be conducted in situ in order to investigate directly the effect of temperature on the different precipitation steps' kinetics. On top of results concerning the size, number density and volumic fraction of precipitates, both the in situ SAXS and ex situ anomalous SAXS experiments will allow to observe the chemical profile inside precipitates. This experiment will provide meaningful insight and results that are essential towards the development of novel Al-Mg-Sc-Zr alloys and their properties modelling.
DOI: 10.15151/esrf-es-903399806
title: Bridging the gap between cellular and whole body imaging using Hierarchical Phase-Contrast Tomography: HiP-CT

description: Humans and other large organisms are three-dimensional multiscale biological systems where large scale function and structure are dependent on the macrostructure’s interconnectivity down to the cellular and subcellular level. Using the exceptional coherence provided by the ESRF-EBS, we have demonstrated that propagation-based phase-contrast can effectively decouple resolution from specimen size in soft tissue, obtaining 1.4 micron voxel resolution in 150 mm diameter human organs. Through this Long Term Proposal (LTP) we will develop the techniques required to image whole human and animal bodies ex vivo at 25 micron resolution, zooming to sub-micron voxels (0.7micron) locally, resolving sub-cellular structures through hard- and soft-tissue. Resolving how the micro (sub-cellular) interacts with the macro (whole organism) across length scales will provide all new insights into biological and biomedical function. This is true for both healthy and pathological system level behaviour.
DOI: 10.15151/esrf-es-945453600
title: In-situ XAS of a Pt anode for Kolbe electro-oxidation of carboxylic acids to alkanes

description: We plan to investigate by in situ XAS the surface of a Pt anode during the Kolbe electro-oxidation of aqueous carboxylic acids. Under reaction conditions, the Pt surface is conditioned, and develops a “barrier layer” which provides high selectivity towards alkanes, while the undesired water oxidation reaction to oxygen in suppressed. We propose to use in situ XAS to investigate (i) the formation and composition of the barrier layer and (ii) the surface structure of the Pt electrode during the Kolbe oxidation of aqueous carboxylic acids. This information, yet unknown to date, is crucial to improve the process selectivity and to develop alternative electrodes composed of earth abundant non-noble materials.
DOI: 10.15151/esrf-es-945455699
title: Magnetic Bragg ptychography imaging of strain and magnetiostriction spin texture tuning in Tb3Fe5O12 epitaxial thin film Spin Seebeck device

description: Spin Seebeck effect (SSE) has received notoriety for the next generation of magnetic device applications, with on-chip spintronic and thermoelectric functionalities. Understanding how crystal structure and strain are intertwined with the magnetic structure in devices is a crucial question underpinning SSE nanotechnology. This enigma could be resolved today thanks to the EBS upgrade, which provides sufficient hard X-ray coherent flux to develop the required tools. We are pioneering a novel 3D magnetic Bragg ptychography microscopy to reveal precisely how crystalline strain causes the magnetic spin texture tuning, in technologically relevant SSE prototype devices structures. This proposal builds on our preliminary results from experiment HC-4336, which have demonstrated the feasibility of obtaining magnetic ptychography reconstructions from the unique experiment set-up provided by ID01. We now require more beamtime to bring the quality of these results towards high impact publication.
DOI: 10.15151/esrf-es-945456750
title: Photoinduced nitroslyl linkage isomers : a time-resolved diffraction study

description: Mononitrosyl complexes of general composition [ML5NO]n± (M=transition metal, L=ligand such as F,Cl,Br, CN, etc) can form linkage isomers upon irradiation with light in the visible spectral range. We aim to measure the structure of the MS2 state, corresponding to a nitrosyl linkage isomer, in sodium nitroprusside (Na2[Fe(CN)5NO]2H2O ) after pulsed laser excitation. Based on ultrafast UV/Vis and infrared spectroscopy, the MS2 state is expected to be occupied within 10 ps. Thus a diffraction experiment with a time resolution of 10-100 ps at room temperature (at room temperature MS2 has a lifetime of 300ns) would prove that SNP has indeed equilibrated in the MS2 minimum after only 10 ps. This experiment would also demonstrate the possibility to capture full structures on single crystals at such a short time scale.
DOI: 10.15151/esrf-es-945457293
title: Effect of x-ray irradiation in structural glasses

description: Glasses are amorphous systems extremely common in our everyday life. Being in a metastable state, they have 'memory' of their history and can be produced in very different ways. With this proposal we want to explore the effect of x-ray irradiation on some prototypical glasses following their structural changes through x-ray diffuse scattering. We will study systems irradiated with different photon energies, investigating the effect of radiolysis and knock-on events.
DOI: 10.15151/esrf-es-945460577
title: HERFD XAS, XES and RIXS study to reveal the electronic structure of single atom doped TiO2 nanocrystals

description: We propose to investigate the role of orbital hybridization in the magnetism of TiO2 and single-atom doped (e.g. Fe, Co, Ni, and Cu) TiO2 nanocrystals using element selective HERFD XAS, XES, and resonant inelastic x-ray scattering (RIXS). The motivation of this work is to find the reason behind the ferromagnetism in the single-atom (e.g. Fe, Co, Ni, and Cu) doped TiO2, an unexpected property with no bulk analogue. These XES/RIXS measurements can uniquely determine whether the observed magnetization is due to a magnetic moment from one of the constituent elements, or their orbital hybridization.
DOI: 10.15151/esrf-es-945469933
title: Band-like/atomic-like duality of dd excitations in cuprates

description: The fascinating properties of high Tc superconducting cuprates are often attributed to the peculiar entwining of sev-eral degrees of freedom (charge density and anisotropy, spin, lattice modes). This implies that the corresponding excitations all have comparable energies, lying in the mid (&lt;500 meV) and far infrared range (&lt;100 meV), and are often of mixed character. Aside to the low energy region, RIXS spectra are dominated by the dd excitations, which are often dismissed as uninteresting. However, two recent experiments are now hinting to band-like effects occurring in the dd excitations of cuprates. We propose to measure the azimuthal (φ) dependence of the dd excitations in the striped cuprate LSCO, at different doping levels, to confirm the existence of unexpected jumps in the dd intensi-ty. The doping, temperature and q dependence of these discontinuities will confirm if this effect is band-like, possi-bly telling us which low energy order is involved in this phenomenology.
DOI: 10.5283/epub.53202
title: Data archive of 'Intersubband Polariton-Polariton Scattering in a Dispersive Microcavity'
DOI: 10.22021/bbldntz202210
title: The Linked Open British National Bibliography – Books. 1950/2022-10 – N-Triples
DOI: 10.22021/bbldrdfz202210
title: The Linked Open British National Bibliography – Books. 1950/2022-10 – RDF/XML
DOI: 10.6084/m9.figshare.21550230.v1
title: The dictionary of corporate sustainable development

description: This is the dictionary of corporate sustainable development. Based on this dictionary, we build the dataset of corporate sustainability disclosure.
DOI: 10.5519/qd.j9ak4x01
title: Query on the Natural History Museum Data Portal (data.nhm.ac.uk) (13097633 records)
DOI: 10.6084/m9.figshare.21378744
title: 3um polystyrene bead & red blood cell & histological slide datasets

description: We shared a part of 3um polystyrene bead, red blood cell, and histological datasets used in the study "<strong>Deep learning based on parameterized physical forward model for adaptive holographic imaging with unpaired data</strong>". <br> 3um polystyrene bead - 300 ground truths - 100 diffraction intensities for each distance (7, 9, 11, 13, 15, and 17mm) <br> red blood cell - 600 ground truths - 600 diffraction intensities for unknwon distance <br> histological slide - 20 ground truths for each tissue type(1-20: duodenum, 21-40: stomach, body, 41-60: stomach, antrum) - 20 diffraction intensities for each tissue type(1-20: small bowel, 21-40: appendix, 41-60: rectum, 61-80: colon) <br> The whole datasets are available from the corresponding author upon reasonable request.
DOI: 10.6084/m9.figshare.21378744.v4
title: 3um polystyrene bead & red blood cell & histological slide datasets

description: We shared a part of 3um polystyrene bead, red blood cell, and histological datasets used in the study "<strong>Deep learning based on parameterized physical forward model for adaptive holographic imaging with unpaired data</strong>". <br> 3um polystyrene bead - 300 ground truths - 100 diffraction intensities for each distance (7, 9, 11, 13, 15, and 17mm) <br> red blood cell - 600 ground truths - 600 diffraction intensities for unknwon distance <br> histological slide - 20 ground truths for each tissue type(1-20: duodenum, 21-40: stomach, body, 41-60: stomach, antrum) - 20 diffraction intensities for each tissue type(1-20: small bowel, 21-40: appendix, 41-60: rectum, 61-80: colon) <br> The whole datasets are available from the corresponding author upon reasonable request.
DOI: 10.6084/m9.figshare.21550230.v2
title: The dictionary of corporate sustainable development

description: This is the dictionary of corporate sustainable development. Based on this dictionary, we build the dataset of corporate sustainability disclosure.
DOI: 10.5281/zenodo.7317654
title: APARENT Data

description: Processed data for the <em>Cell</em> article "A Deep Neural Network for Predicting and Engineering Alternative Polyadenylation" (https://doi.org/10.1016/j.cell.2019.04.046). See Github page for information about data content and format (https://github.com/johli/aparent).
DOI: 10.5281/zenodo.7317653
title: APARENT Data

description: Processed data for the <em>Cell</em> article "A Deep Neural Network for Predicting and Engineering Alternative Polyadenylation" (https://doi.org/10.1016/j.cell.2019.04.046). See Github page for information about data content and format (https://github.com/johli/aparent).
DOI: 10.6084/m9.figshare.21550230.v3
title: The dictionary of corporate sustainable development

description: This is the dictionary of corporate sustainable development. Based on this dictionary, we build the dataset of corporate sustainability disclosure.
DOI: 10.6084/m9.figshare.21550155.v1
title: Information disclosure index of sustainable development of listed firms in China 2010-2019

description: This is the dataset on corporate sustainability disclosure of Chinese listed firms in 2010-2019. This dataset includes the Corporate Sustainability Disclosure Index (CSDI), CSDI_Economic Dimension (CSDI_ECO), CSDI_Environmental Dimension (CSDI_ENV), and CSDI_Social Dimension (CSDI_SOCI).
DOI: 10.7910/dvn/pg51ez/c98wxj
title: G3_rohu_tagging_data-1.tab

description: Data
DOI: 10.5281/zenodo.7317835
title: In situ tuning of dynamical Coulomb blockade in hybrid nanowire devices

description: This repository contains the raw data and processing Python scripts corresponding to the paper "In situ tuning of dynamical Coulomb blockade in hybrid nanowire devices"
DOI: 10.5281/zenodo.7317834
title: In situ tuning of dynamical Coulomb blockade in hybrid nanowire devices

description: This repository contains the raw data and processing Python scripts corresponding to the paper "In situ tuning of dynamical Coulomb blockade in hybrid nanowire devices"
DOI: 10.6084/m9.figshare.21550155
title: Information disclosure index of sustainable development of listed firms in China 2010-2019

description: This is the dataset on corporate sustainability disclosure of Chinese listed firms in 2010-2019. This dataset includes the Corporate Sustainability Disclosure Index (CSDI), CSDI_Economic Dimension (CSDI_ECO), CSDI_Environmental Dimension (CSDI_ENV), and CSDI_Social Dimension (CSDI_SOCI).
DOI: 10.6084/m9.figshare.21550155.v2
title: Information disclosure index of sustainable development of listed firms in China 2010-2019

description: This is the dataset on corporate sustainability disclosure of Chinese listed firms in 2010-2019. This dataset includes the Corporate Sustainability Disclosure Index (CSDI), CSDI_Economic Dimension (CSDI_ECO), CSDI_Environmental Dimension (CSDI_ENV), and CSDI_Social Dimension (CSDI_SOCI).
DOI: 10.6084/m9.figshare.21550230
title: The dictionary of corporate sustainable development

description: This is the dictionary of corporate sustainable development. Based on this dictionary, we build the dataset of corporate sustainability disclosure.
DOI: 10.6084/m9.figshare.21550230.v4
title: The dictionary of corporate sustainable development

description: This is the dictionary of corporate sustainable development. Based on this dictionary, we build the dataset of corporate sustainability disclosure.
DOI: 10.15151/esrf-es-945453089
title: XAFS investigation of the electronic and structural properties of Ga dopant in SiGe and pure Ge epitaxial layers for MOSFET applications

description: The goal of this proposal is to use X-ray absorption Fine Structure (XAFS) to investigate the electronic and structural properties of Ga atoms in series of novel Ga doped epitaxial SiGe and pure Ge epitaxial layers grown on Si that hold great promise for the development of next generation ultra-scaled p-type MOSFETs devices. This investigation will provide a better understanding of the electronic and structural properties of the Ga-based defect complexes formed in the SiGe and Ge lattices during chemical vapor deposition (CVD), as a function of the Ga concentration. Additionally, the structure of the superficial segregated Ga phases obtained at high Ga concentrations will be investigated. This will be used as input parameter to guide further the Density Functional Theory (DFT) calculations of the electronic properties and local environment of the different Ga-defect complexes formed (e.g.: Ga-vacancy, Ga-Si/Ge interstitials, Ga clusters).
DOI: 10.6084/m9.figshare.21476642
title: <i>IRF1</i> expression might be a biomarker of CD8+ T cell infiltration in cutaneous melanoma

description: This study aimed to explore the expression profile of interferon regulatory factor (IRF) genes in skin cutaneous melanoma (SKCM), their association with CD8 + T cell infiltration, and the potential regulatory network in melanoma and non-melanoma cells. Bioinformatic analysis was conducted using the SKCM subset of The Cancer Genome Atlas (TCGA) Pan-Cancer, Genotype-Tissue Expression Project (GTEx), and single-cell RNA-seq data from the Human Protein Atlas and Jerby-Arnon et al. 2018ʹs dataset. <i>IRF1</i> expression is robustly associated with moderate to strong CD8 + T cell infiltration in the tumor microenvironment. It is ubiquitously expressed in tumor and non-tumor cells in melanoma. Melanoma tumor cells and macrophages had 16/36 and 9/27 cell-specific <i>IRF1</i>-correlated genes, respectively. The methylation of four CpG sites (cg00255919, cg21138405, cg15375424, and cg27587780) within the <i>IRF1</i> gene locus showed moderate to strong negative correlations with <i>IRF1</i> expression. <i>IRF1</i> expression might serve as a biomarker indicating CD8 + T cell infiltration in skin melanoma. It might exert different regulatory effects in melanoma and non-melanoma cells in the tumor microenvironment. Cg00255919, cg21138405, cg15375424, and cg27587780 are four critical CpG sites that might modulate the transcription of <i>IRF1</i>.