cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.6984578.v1
title: The association between the etiology of a spinal cord injury and time to mortality in the United States: A 44-year investigation

description: <b>Objective:</b> To determine the association between spinal cord injury (SCI) etiology categories and mortality, and examine the association between etiology sub-categories and mortality. <b>Design:</b> Prospective cohort study. <b>Setting</b>: Model Systems and Shriners Hospital SCI units. <b>Participants</b>: Data were analyzed from 42,627 cases in the SCI Model System Collaborative Survival Study Database from 1973 to 2017. Those with SCI etiologies categorized as vehicular, violent, sports, falls, pedestrian, and medical were included. <b>Interventions</b>: Not applicable. <b>Outcome Measure</b>: Time to mortality after SCI. <b>Results:</b> Relative to the sports related etiology category, those with medical, pedestrian, violence, falls, and vehicular related SCIs had a 2.00 (95% confidence intervals (CIs): 1.79–2.24), 1.57 (CIs: 1.34–1.83), 1.54 (CIs: 1.41–1.68), 1.35 (CIs: 1.25–1.45), and 1.26 (CIs: 1.17–1.35) higher hazard for mortality, respectfully. Persons with SCIs from automobile crashes had a 1.38 (CIs: 1.23–1.56) higher hazard for mortality, whereas those with SCIs from motorcycle crashes had a 1.21 (CIs: 1.04–1.39) higher hazard for mortality, relative to other etiologies within the vehicular category. Those with SCIs from diving had a 1.37 (CIs: 1.18–1.59) higher hazard for mortality relative to other etiologies within the sports category. <b>Conclusions:</b> Injury etiology categories and certain sub-categories were associated with a higher risk for early mortality. Understanding how additional factors such as socioeconomic status, co-occurring injuries, medical co-morbidities, and environmental aspects interact with SCI etiologies may provide insights for how etiology of injury impacts survival. These findings may serve as a development for extending long-term life expectancy by informing SCI prevention programs and care post-injury.
DOI: 10.6084/m9.figshare.6984515
title: Risk Data_20082018.xlsx

description: Data used to construct risk index which quantifies trade risk in the economies of the SACU member states
DOI: 10.6084/m9.figshare.6984443
title: EEDP.pdf

description: Riesgo de suicidio en enonatos
DOI: 10.6084/m9.figshare.6984431
title: “Out of the can”: a draft genome assembly, liver transcriptome and nutrigenomics of the European sardine, Sardina pilchardus

description: Clupeiformes, such as sardines and herrings, represent an important share of worldwide fisheries. Among those, the European sardine (Sardina pilchardus, Walbaum 1792) exhibits significant commercial relevance. While the last decade showed a steady and sharp decline in capture levels, recent advances in culture husbandry represent promising research avenues. Yet, the complete absence of genomic resources from sardine imposes a severe bottleneck to understand its physiological and ecological requirements. We generated 69 Gbp of paired-end reads using Illumina HiSeq X Ten and assembled a draft genome assembly with an N50 scaffold length of 25,579 bp and BUSCO completeness of 82.1% (Actinopterygii). The estimated size of the genome ranges between 655 and 850 Mb. Additionally, we generated a relatively high-level liver transcriptome. To deliver a proof of principle of the value of this dataset, we established the presence and function of enzymes (Elovl2, Elovl5, and Fads2) that have pivotal roles in the biosynthesis of long chain polyunsaturated fatty acids, essential nutrients particularly abundant in oily fish such as sardines. Our study provides the first omics dataset from a valuable economic marine teleost species, the European sardine, representing an essential resource for their effective conservation, management, and sustainable exploitation.
DOI: 10.6084/m9.figshare.6984431.v1
title: “Out of the can”: a draft genome assembly, liver transcriptome and nutrigenomics of the European sardine, Sardina pilchardus

description: Clupeiformes, such as sardines and herrings, represent an important share of worldwide fisheries. Among those, the European sardine (Sardina pilchardus, Walbaum 1792) exhibits significant commercial relevance. While the last decade showed a steady and sharp decline in capture levels, recent advances in culture husbandry represent promising research avenues. Yet, the complete absence of genomic resources from sardine imposes a severe bottleneck to understand its physiological and ecological requirements. We generated 69 Gbp of paired-end reads using Illumina HiSeq X Ten and assembled a draft genome assembly with an N50 scaffold length of 25,579 bp and BUSCO completeness of 82.1% (Actinopterygii). The estimated size of the genome ranges between 655 and 850 Mb. Additionally, we generated a relatively high-level liver transcriptome. To deliver a proof of principle of the value of this dataset, we established the presence and function of enzymes (Elovl2, Elovl5, and Fads2) that have pivotal roles in the biosynthesis of long chain polyunsaturated fatty acids, essential nutrients particularly abundant in oily fish such as sardines. Our study provides the first omics dataset from a valuable economic marine teleost species, the European sardine, representing an essential resource for their effective conservation, management, and sustainable exploitation.
DOI: 10.6084/m9.figshare.6984338
title: Supplementary Material for: Prevalence of Actinic Keratosis in Patients Attending General Practitioners in Switzerland

description: <b><i>Background:</i></b> Most of the data concerning the prevalence of actinic keratosis (AK) originate from the USA and Australia, and recently from Austria and Spain, but are based on populations in dermatology practices. Switzerland is the leading country with skin cancer incidence in Europe. AK prevalence among the Swiss population is therefore an important public health issue. <b><i>Objective:</i></b> To assess the prevalence of AK in the outpatient Swiss population in general practice. <b><i>Methods:</i></b> General practitioners captured AK diagnosis stage and localization in consecutive patients, who attended the physician for any reason. <b><i>Results:</i></b> A total of 2,844 consecutive patients (55.7% female) were enrolled in 59 general practitioners’ offices. AK prevalence was 25.3% and increased steadily with age; 33% of men and 19% of women were diagnosed with AK. Every second AK patient declared leisure-related UV exposure, while only 23% were exposed to UV occupationally; 16% of the patients were UV exposed both occupationally and during leisure. AK distribution among sun-exposed body sites and extent of disease varied by sex. <b><i>Conclusion:</i></b> In Switzerland AK is a common diagnosis in dermatology practices. Since up to 5% of AK may progress to invasive squamous cell carcinoma (SCC), prevention of AK, as well as education of patients and general practitioners, may play a critical role for subsequent SCC development. This is the first study on AK prevalence in Switzerland identifying patients most affected by AK. These results will help to define future approaches to target general practitioners for education, screening, and specific intervention in patients with AK.
DOI: 10.6084/m9.figshare.6984338.v1
title: Supplementary Material for: Prevalence of Actinic Keratosis in Patients Attending General Practitioners in Switzerland

description: <b><i>Background:</i></b> Most of the data concerning the prevalence of actinic keratosis (AK) originate from the USA and Australia, and recently from Austria and Spain, but are based on populations in dermatology practices. Switzerland is the leading country with skin cancer incidence in Europe. AK prevalence among the Swiss population is therefore an important public health issue. <b><i>Objective:</i></b> To assess the prevalence of AK in the outpatient Swiss population in general practice. <b><i>Methods:</i></b> General practitioners captured AK diagnosis stage and localization in consecutive patients, who attended the physician for any reason. <b><i>Results:</i></b> A total of 2,844 consecutive patients (55.7% female) were enrolled in 59 general practitioners’ offices. AK prevalence was 25.3% and increased steadily with age; 33% of men and 19% of women were diagnosed with AK. Every second AK patient declared leisure-related UV exposure, while only 23% were exposed to UV occupationally; 16% of the patients were UV exposed both occupationally and during leisure. AK distribution among sun-exposed body sites and extent of disease varied by sex. <b><i>Conclusion:</i></b> In Switzerland AK is a common diagnosis in dermatology practices. Since up to 5% of AK may progress to invasive squamous cell carcinoma (SCC), prevention of AK, as well as education of patients and general practitioners, may play a critical role for subsequent SCC development. This is the first study on AK prevalence in Switzerland identifying patients most affected by AK. These results will help to define future approaches to target general practitioners for education, screening, and specific intervention in patients with AK.
DOI: 10.6084/m9.figshare.6984323
title: Shower data from six hotels

description: Shower data (water consumption, average temperature, flow rate, energy) collected in six different Swiss hotels in 2016.
DOI: 10.6084/m9.figshare.6984323.v2
title: Shower data from six hotels

description: Shower data (water consumption, average temperature, flow rate, energy) collected in six different Swiss hotels in 2016.
DOI: 10.6084/m9.figshare.6984314
title: Publication of raw and curated NMR spectroscopic data for organic molecules

description: Talk delivered on 20 August 2018 at the CINF session on sharing research data at the ACS Meeting in Boston
DOI: 10.6084/m9.figshare.6984296
title: Six months on - NHS England needs to focus on dissemination, implementation and audit of its Low Priority Initiative

description: Results and analytic code to show the prescribing over time of 17 medicines identified as "low-value" by NHS England.
DOI: 10.6084/m9.figshare.6984296.v1
title: The NHS England “low-priority medicines initiative” has had minimal impact on prescribing

description: Results and analytic code to show the prescribing over time of 17 medicines identified as "low-value" by NHS England.
DOI: 10.6084/m9.figshare.6984290
title: RhoA controls retinoid signaling by ROCK dependent regulation of retinol metabolism

description: The ubiquitously expressed small GTPase RhoA is essential for embryonic development and mutated in different cancers. Functionally, it is well described as a regulator of the actin cytoskeleton, but its role in gene regulation is less understood. Using primary mouse keratinocytes with a deletion of the RhoA gene, we have now been exploring how the loss of RhoA affects gene expression. Performing transcription factor reporter assays, we found a significantly decreased activity of a RAR luciferase reporter in RhoA-null keratinocytes. Inhibition of the RhoA effector ROCK in control cells reproduced this phenotype. ATRA and retinal, but not retinol increased RAR reporter activity of keratinocytes with impaired RhoA/ROCK signaling, suggesting that retinol metabolism is regulated by RhoA/ROCK signaling. Furthermore a significant percentage of known ATRA target genes displayed altered expression in RhoA-null keratinocytes. These data reveal an unexpected link between the cytoskeletal regulator RhoA and retinoid signaling and uncover a novel pathway by which RhoA regulates gene expression.
DOI: 10.6084/m9.figshare.6984296.v2
title: Six months on - NHS England needs to focus on dissemination, implementation and audit of its Low Priority Initiative

description: Results and analytic code to show the prescribing over time of 17 medicines identified as "low-value" by NHS England.
DOI: 10.6084/m9.figshare.6984290.v1
title: RhoA controls retinoid signaling by ROCK dependent regulation of retinol metabolism

description: The ubiquitously expressed small GTPase RhoA is essential for embryonic development and mutated in different cancers. Functionally, it is well described as a regulator of the actin cytoskeleton, but its role in gene regulation is less understood. Using primary mouse keratinocytes with a deletion of the RhoA gene, we have now been exploring how the loss of RhoA affects gene expression. Performing transcription factor reporter assays, we found a significantly decreased activity of a RAR luciferase reporter in RhoA-null keratinocytes. Inhibition of the RhoA effector ROCK in control cells reproduced this phenotype. ATRA and retinal, but not retinol increased RAR reporter activity of keratinocytes with impaired RhoA/ROCK signaling, suggesting that retinol metabolism is regulated by RhoA/ROCK signaling. Furthermore a significant percentage of known ATRA target genes displayed altered expression in RhoA-null keratinocytes. These data reveal an unexpected link between the cytoskeletal regulator RhoA and retinoid signaling and uncover a novel pathway by which RhoA regulates gene expression.
DOI: 10.6084/m9.figshare.6984272
title: Harry Potter and the Chamber of <i>What</i>?: the impact of what individuals know on word processing during reading

description: During reading, effects of contextual support indexed by N400 – a brain potential sensitive to semantic activation/retrieval – amplitude are presumably mediated by comprehenders’ world knowledge. Moreover, variability in knowledge may influence the contents, timing, and mechanisms of what is brought to mind during real-time sentence processing. Since it is infeasible to assess the entirety of each individual’s knowledge, we investigated a limited domain – the narrative world of Harry Potter (HP). We recorded event-related brain potentials while participants read sentences ending in words more/less contextually supported. For sentences about HP, but not about general topics, contextual N400 effects were graded according to individual participants’ HP knowledge. Our results not only confirm that context affects semantic processing by ∼250 ms or earlier, on average, but empirically demonstrate what has until now been assumed – that N400 context effects are a function of each individual’s knowledge, which here is highly correlated with their reading experience.
DOI: 10.6084/m9.figshare.6984266
title: Periphytic diatoms of the Mediterranean karst spring Sa Vena (Su Gologone system, Sardinia, Italy): relationships with environmental variables and effects of an extreme flash flood

description: In Sardinia, Italy, karst springs are strategic water resources and potential hotspots of biodiversity; however, they are understudied, and their communities remain largely unknown. This study was conducted at Sa Vena spring (Su Gologone system) to characterize the diatom communities, to describe their relationships with environmental variables, and to evaluate the impact of an extreme flash flood. High species richness, diversity, and evenness were found both in epiphytic and epilithic assemblages. Statistical analyses showed significant differences between assemblages from the 2 substrates and in assemblages from the same substrate. Differences seem due to the stronger impact of seasonal water level variations and flash flood on macrophytes than on cobbles. Further, epilithic assemblages showed more stable behavior over time, both on an annual (higher resistence) and a multiannual (higher resilience) scale. Alkalinity (<i>p</i> = 0.002) and dissolved oxygen (<i>p</i> = 0.004) explained a significant amount of variance in epiphytic and epilithic assemblages, respectively, according to RDA analyses; however BOD<sub>5</sub>, negatively correlated with dissolved oxygen, can be the most probable driver of epilithic diatoms. The results suggest the importance of the proper management and preservation of this biotope, both for the high biodiversity and potential vulnerability to climate change.
DOI: 10.6084/m9.figshare.6984266.v1
title: Periphytic diatoms of the Mediterranean karst spring Sa Vena (Su Gologone system, Sardinia, Italy): relationships with environmental variables and effects of an extreme flash flood

description: In Sardinia, Italy, karst springs are strategic water resources and potential hotspots of biodiversity; however, they are understudied, and their communities remain largely unknown. This study was conducted at Sa Vena spring (Su Gologone system) to characterize the diatom communities, to describe their relationships with environmental variables, and to evaluate the impact of an extreme flash flood. High species richness, diversity, and evenness were found both in epiphytic and epilithic assemblages. Statistical analyses showed significant differences between assemblages from the 2 substrates and in assemblages from the same substrate. Differences seem due to the stronger impact of seasonal water level variations and flash flood on macrophytes than on cobbles. Further, epilithic assemblages showed more stable behavior over time, both on an annual (higher resistence) and a multiannual (higher resilience) scale. Alkalinity (<i>p</i> = 0.002) and dissolved oxygen (<i>p</i> = 0.004) explained a significant amount of variance in epiphytic and epilithic assemblages, respectively, according to RDA analyses; however BOD<sub>5</sub>, negatively correlated with dissolved oxygen, can be the most probable driver of epilithic diatoms. The results suggest the importance of the proper management and preservation of this biotope, both for the high biodiversity and potential vulnerability to climate change.
DOI: 10.6084/m9.figshare.6984272.v1
title: Harry Potter and the Chamber of <i>What</i>?: the impact of what individuals know on word processing during reading

description: During reading, effects of contextual support indexed by N400 – a brain potential sensitive to semantic activation/retrieval – amplitude are presumably mediated by comprehenders’ world knowledge. Moreover, variability in knowledge may influence the contents, timing, and mechanisms of what is brought to mind during real-time sentence processing. Since it is infeasible to assess the entirety of each individual’s knowledge, we investigated a limited domain – the narrative world of Harry Potter (HP). We recorded event-related brain potentials while participants read sentences ending in words more/less contextually supported. For sentences about HP, but not about general topics, contextual N400 effects were graded according to individual participants’ HP knowledge. Our results not only confirm that context affects semantic processing by ∼250 ms or earlier, on average, but empirically demonstrate what has until now been assumed – that N400 context effects are a function of each individual’s knowledge, which here is highly correlated with their reading experience.
DOI: 10.6084/m9.figshare.6984221
title: Data_article_Changes in the West African forest-savanna mosaic, insights from central Togo

description: satellite images, questionnaire data, data collection<br>
DOI: 10.6084/m9.figshare.6984221.v1
title: Data_article_Changes in the West African forest-savanna mosaic, insights from central Togo

description: satellite images, questionnaire data, data collection<br>
DOI: 10.7284/107615
title: Multibeam Echosounder data collected during research cruise MGL0801 using a Kongsberg EM120 instrument system onboard the platform RV Marcus G. Langseth
DOI: 10.6084/m9.figshare.6984251.v2
title: Channelings

description: Materials related to the Channelings Interviews:<br>N_date= original interviews in Italian with the channeler NE_date= original interviews in Italian with the channeler E
DOI: 10.6084/m9.figshare.6984251.v3
title: Channelings

description: Materials related to the Channelings Interviews:<br>N_date= original interviews in Italian with the channeler NE_date= original interviews in Italian with the channeler ED_date= original interviews in Italian with the channeler D
DOI: 10.6084/m9.figshare.6984206
title: Functional diversity of the world freshwater fish faunas

description: Zipped file containing csv tables with information on the global distribution of freshwater fish species functional traits, basin occurrences, and taxonomic and functional indices.
DOI: 10.6084/m9.figshare.6984251.v4
title: Channelings

description: Materials related to the Channelings Interviews:<br>N_date= original interviews in Italian with the channeler NE_date= original interviews in Italian with the channeler ED_date= original interviews in Italian with the channeler DGroup_date = original group interviews in Italian<br>
DOI: 10.6084/m9.figshare.6984251.v5
title: Channelings

description: Materials related to the Channelings Interviews:<br>N_date= original audio interviews in Italian with the channeler NE_date= original audio interviews in Italian with the channeler ED_date= original audio interviews in Italian with the channeler DGroup_date = original audio group interviews in ItalianMultiple channelings_date = English translation of multiple channelings interview<br><br>
DOI: 10.6084/m9.figshare.6984251.v6
title: Channelings

description: Materials related to the Channelings Interviews:<br>N_date= original audio interviews in Italian with the channeler NE_date= original audio interviews in Italian with the channeler ED_date= original audio interviews in Italian with the channeler DGroup_date = original audio group interviews in ItalianMultiple channelings_date = English translation of multiple channelings interviews<br><br>
DOI: 10.6084/m9.figshare.6984251.v7
title: Channelings

description: Materials related to the Channelings Interviews:<br>N_date= original audio interviews in Italian with the channeler NE_date= original audio interviews in Italian with the channeler ED_date= original audio interviews in Italian with the channeler DGroup_date = original audio group interviews in ItalianGroup Channeling while in Hypnobe = English translation of multiple channelings interviews<br><br>
DOI: 10.6084/m9.figshare.6984251.v8
title: Channelings

description: Materials related to the Channelings Interviews:<br>N_date= original audio interviews in Italian with the channeler NE_date= original audio interviews in Italian with the channeler ED_date= original audio interviews in Italian with the channeler DGroup_date = original audio group interviews in ItalianGroup Channelings while in Hypnobe = English translation of multiple channelings interviews<br><br>
DOI: 10.6084/m9.figshare.6984050
title: Untitled ItemComplications of planned home births in the Czech Republic 2016-2017

description: This prospective cohort observational study is based on an analysis of cases of women with complications of planned domestic childbirth in the Czech Republic between 2016 and 2017. The data collection was carried out using an on-line form accessible to all maternity hospitals in the Czech Republic.
DOI: 10.6084/m9.figshare.6984050.v1
title: Untitled ItemComplications of planned home births in the Czech Republic 2016-2017

description: This prospective cohort observational study is based on an analysis of cases of women with complications of planned domestic childbirth in the Czech Republic between 2016 and 2017. The data collection was carried out using an on-line form accessible to all maternity hospitals in the Czech Republic.
DOI: 10.7284/102430
title: INS (Inertial Navigation System) data collected during research cruise MGL0804 using a Kongsberg Seapath 200 instrument system onboard the platform RV Marcus G. Langseth