cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.14113532
title: Supplementary Material for: What Can Be Done to Solve the Unmet Clinical Need of Hepatocellular Carcinoma Patients following Lenvatinib Failure?

description: <b><i>Background/Aim:</i></b> An effective postprogression treatment of lenvatinib (LEN) against unresectable hepatocellular carcinoma (u-HCC) has not been established. We aimed to elucidate the clinical role of continuing LEN beyond progression of disease (PD). <b><i>Methods:</i></b> From March 2018 to October 2020, 99 u-HCC patients, in whom PD was confirmed (male:female = 78:21, median age 72 years, Child-Pugh A = 99, Barcelona Clinic Liver Cancer stage A:B:C = 2:43:54, LEN as first-line = 55), were enrolled (stopped LEN at PD [A group], <i>n</i> = 26; continued LEN beyond PD [B group], <i>n</i> = 73). Radiological response was evaluated with RECIST 1.1. Clinical features and prognostic factors for overall survival (OS) were retrospectively investigated using inverse probability weighting (IPW) calculated by propensity score. <b><i>Results:</i></b> Median time to progression, best response, and modified albumin-bilirubin grade (mALBI) at both baseline and PD did not show significant difference between the groups. Postprogression treatment in the A group was best supportive care in 17, sorafenib in 4, regorafenib in 3, ramucirumab in 1, and hepatic arterial infusion chemotherapy in 1. After adjusting with IPW, the B group showed better prognosis in regard to OS after PD and OS after introducing LEN than the A group (10.8/19.6 vs. 5.8/11.2 months, <i>p</i> &lt; 0.001, respectively). In IPW-adjusted Cox hazard multivariate analysis, significant prognostic factors for OS after PD were mALBI 2b/3 at PD (HR 1.983, <i>p</i> = 0.021), decline of Eastern Cooperative Oncology Group performance status (ECOG PS) from baseline at PD (HR 3.180, <i>p</i> &lt; 0.001), elevated alpha-fetoprotein (≥100 ng/mL) at introducing LEN (HR 2.511, <i>p</i> = 0.004), appearance of new extrahepatic metastasis (HR 2.396, <i>p</i> = 0.006), positive for hand-foot skin reaction (HFSR) before PD (any grade) (HR 0.292, <i>p</i> &lt; 0.001), and continuing LEN beyond PD (HR 0.297, <i>p</i> &lt; 0.001). <b><i>Conclusion:</i></b> When ECOG PS and hepatic reserve function permit, continuing LEN treatment beyond PD, especially in u-HCC patients showed HFSR during LEN treatment, might be a good therapeutic option, at least until a more effective drug as a postprogression treatment after LEN failure is developed.
DOI: 10.6084/m9.figshare.14113532.v1
title: Supplementary Material for: What Can Be Done to Solve the Unmet Clinical Need of Hepatocellular Carcinoma Patients following Lenvatinib Failure?

description: <b><i>Background/Aim:</i></b> An effective postprogression treatment of lenvatinib (LEN) against unresectable hepatocellular carcinoma (u-HCC) has not been established. We aimed to elucidate the clinical role of continuing LEN beyond progression of disease (PD). <b><i>Methods:</i></b> From March 2018 to October 2020, 99 u-HCC patients, in whom PD was confirmed (male:female = 78:21, median age 72 years, Child-Pugh A = 99, Barcelona Clinic Liver Cancer stage A:B:C = 2:43:54, LEN as first-line = 55), were enrolled (stopped LEN at PD [A group], <i>n</i> = 26; continued LEN beyond PD [B group], <i>n</i> = 73). Radiological response was evaluated with RECIST 1.1. Clinical features and prognostic factors for overall survival (OS) were retrospectively investigated using inverse probability weighting (IPW) calculated by propensity score. <b><i>Results:</i></b> Median time to progression, best response, and modified albumin-bilirubin grade (mALBI) at both baseline and PD did not show significant difference between the groups. Postprogression treatment in the A group was best supportive care in 17, sorafenib in 4, regorafenib in 3, ramucirumab in 1, and hepatic arterial infusion chemotherapy in 1. After adjusting with IPW, the B group showed better prognosis in regard to OS after PD and OS after introducing LEN than the A group (10.8/19.6 vs. 5.8/11.2 months, <i>p</i> &lt; 0.001, respectively). In IPW-adjusted Cox hazard multivariate analysis, significant prognostic factors for OS after PD were mALBI 2b/3 at PD (HR 1.983, <i>p</i> = 0.021), decline of Eastern Cooperative Oncology Group performance status (ECOG PS) from baseline at PD (HR 3.180, <i>p</i> &lt; 0.001), elevated alpha-fetoprotein (≥100 ng/mL) at introducing LEN (HR 2.511, <i>p</i> = 0.004), appearance of new extrahepatic metastasis (HR 2.396, <i>p</i> = 0.006), positive for hand-foot skin reaction (HFSR) before PD (any grade) (HR 0.292, <i>p</i> &lt; 0.001), and continuing LEN beyond PD (HR 0.297, <i>p</i> &lt; 0.001). <b><i>Conclusion:</i></b> When ECOG PS and hepatic reserve function permit, continuing LEN treatment beyond PD, especially in u-HCC patients showed HFSR during LEN treatment, might be a good therapeutic option, at least until a more effective drug as a postprogression treatment after LEN failure is developed.
DOI: 10.5281/zenodo.4561894
title: Experimental data of the paper entitled: Simulation of COVID-19 propagation scenarios in the Madrid metropolitan area

description: Experimental data of the paper: Simulation of COVID-19 propagation scenarios in the Madrid metropolitan area<br> David E. Singh*,Maria-cristina Marinescu,Miguel Guzman-Merino,Christian Duran,Concepción Delgado-Sanz,<br> Diana Gomez-Barroso,Jesus Carretero<br> Front. Public Health - Infectious Diseases DOI: 10.3389/fpubh.2021.636023 Dataset structure: * Each directory corresponds to each scenario presented in the paper<br> * Each directory contains in each sub-directory each one of the experiments (simulations) run<br> * For each sub-directory the contents are:<br> - citylist.txt -&gt; The cities considered in the simulation<br> - output.txt -&gt; the simulation output<br> - xml directory:<br> - XMLCityConfigFile.xml -&gt; Configuration file with the city list <br> - XMLConfigFile.xml -&gt; Main configuration file<br> - xmlCityName:<br> - distances.dat -&gt; Distance vector with other cities configured in the simulator<br> - id.dat -&gt; city's id<br> - location.dat -&gt; city's location<br> - nuts.dat -&gt; city's NUTS code<br> - XMLConfigFile.xml -&gt; COVID-19 configuration parameters<br> - XMLGraphConfigFile.xml -&gt; city's configuration parameters
DOI: 10.5281/zenodo.4561893
title: Experimental data of the paper entitled: Simulation of COVID-19 propagation scenarios in the Madrid metropolitan area

description: Experimental data of the paper: Simulation of COVID-19 propagation scenarios in the Madrid metropolitan area<br> David E. Singh*,Maria-cristina Marinescu,Miguel Guzman-Merino,Christian Duran,Concepción Delgado-Sanz,<br> Diana Gomez-Barroso,Jesus Carretero<br> Front. Public Health - Infectious Diseases DOI: 10.3389/fpubh.2021.636023 Dataset structure: * Each directory corresponds to each scenario presented in the paper<br> * Each directory contains in each sub-directory each one of the experiments (simulations) run<br> * For each sub-directory the contents are:<br> - citylist.txt -&gt; The cities considered in the simulation<br> - output.txt -&gt; the simulation output<br> - xml directory:<br> - XMLCityConfigFile.xml -&gt; Configuration file with the city list <br> - XMLConfigFile.xml -&gt; Main configuration file<br> - xmlCityName:<br> - distances.dat -&gt; Distance vector with other cities configured in the simulator<br> - id.dat -&gt; city's id<br> - location.dat -&gt; city's location<br> - nuts.dat -&gt; city's NUTS code<br> - XMLConfigFile.xml -&gt; COVID-19 configuration parameters<br> - XMLGraphConfigFile.xml -&gt; city's configuration parameters
DOI: 10.17033/data.00000153
title: Joint Air Quality Initiative (JOAQUIN)

description: "The project translated the science of new and emerging health relevant pollutants (UFP, EC) into practice. We obtained data and information on the current local and regional situations and improved the collective understanding of air pollution and its impact on citizens’ health. This resulted in truly health relevant information that is crucial to increase the capacity of air quality experts, authorities and public health professionals in order to facilitate and provide the motivation for better air quality policies. For your convenience we created several general reports with our scientific findings on ultrafine particles (UFP) in NW Europe, the chemical composition of particulate matter across NW Europe and a case study on the genotoxic effects of particulate matter." (www.joaquin.eu; 2021)
description: Ultrafine Particles: TSI 3031 Ultrafine Particle Monitor Total PM1 number concentration: TSI 3783 Environmental Particle Counter Black Carbon: Thermo 5012 Multiangle Absorption Photometer (MAAP) Other parameters taken from: https://uk-air.defra.gov.uk/
DOI: 10.48370/ofd/bsxrdm/ydcatc
title: 1047-0002.jpg

description: :unav
DOI: 10.48370/ofd/bsxrdm
title: Krwawnik pannoński (Achillea pannonica Scheele), 2699

description: Herbarium
DOI: 10.5517/ccv1lxc
title: CCDC 776113: Experimental Crystal Structure Determination

description: Related Article: C.A.Tovee, C.A.Kilner, J.A.Thomas, M.A.Halcrow|2010|CSD Communication|||
DOI: 10.5517/ccv1lwb
title: CCDC 776112: Experimental Crystal Structure Determination

description: Related Article: C.A.Tovee, C.A.Kilner ,J.A.Thomas, M.A.Halcrow|2010|CSD Communication|||
DOI: 10.5255/ukda-sn-854373
title: An evaluation of short earth science continuing professional development for trainee primary school teachers, 2009-2015

description: The comments from 1395 evaluation forms completed by 25% trainee teachers participating in earth science workshops were used to ascertain whether the workshops contributed to teaching practices and teacher confidence. The workshops took place in English teacher training establishments between 2009 and 2015. The background qualifications of the trainees, and their confidence at teaching science prior to the workshop were investigated. The evaluation responses of the participants were analysed thematically (Braun & Clarke, 2006) and it was found that these themes related very closely to Guskey’s (2000) categories as being important outcomes for effective Continuing Professional Development (CPD). The workshops provided informative, accurate subject content knowledge which could be used along with the pedagogical content knowledge for trainees and teachers with little science background. The trainees stated that they felt confident in using the workshop ideas; that they could adapt these ideas to their own teaching styles and that the simple but effective resources were easily available for use. The workshops provided the knowledge and understanding of the subject a teacher needed prior to offering it as a lesson, seen as being very important (Harlen and Elstgeest (1992). The workshops showed that they could indeed fulfil a need effectively in a short workshop providing confidence and reliable teaching content.
DOI: 10.6084/m9.figshare.13198259
title: High-resolution surface faulting from the 1983 Idaho Lost River Fault Mw 6.9 earthquake and previous events

description: This dataset contains key characteristics about the data described in the Data Descriptor High-resolution surface faulting from the 1983 Idaho Lost River Fault Mw 6.9 earthquake and previous events. <br> Contents: <br> 1. human readable metadata summary table in CSV format 2. machine readable metadata file in JSON format
DOI: 10.6084/m9.figshare.13198259.v1
title: High-resolution surface faulting from the 1983 Idaho Lost River Fault Mw 6.9 earthquake and previous events

description: This dataset contains key characteristics about the data described in the Data Descriptor High-resolution surface faulting from the 1983 Idaho Lost River Fault Mw 6.9 earthquake and previous events. <br> Contents: <br> 1. human readable metadata summary table in CSV format 2. machine readable metadata file in JSON format
DOI: 10.6084/m9.figshare.13562570
title: A SARS-CoV-2 cytopathicity dataset generated by high-content screening of a large drug repurposing collection

description: This dataset contains key characteristics about the data described in the Data Descriptor A SARS-CoV-2 cytopathicity dataset generated by high-content screening of a large drug repurposing collection. <br> Contents: <br> 1. human readable metadata summary table in CSV format 2. machine readable metadata file in JSON format
DOI: 10.5281/zenodo.4557334
title: IUCLID templates for PPP Risk Assessment - Template 5.3 - Template summary table integrating experimental evidence on genotoxicity for metabolites

description: This word file contains the <strong>template for a summary table integrating experimental evidence on genotoxicity for metabolites</strong>. The filled-in template shall be uploaded in Attached (sanitised) documents for publication <strong>under 5.4 Genotoxicity testing-endpoint summary</strong> or alternatively by filling in an HTML table <strong>in the description of key information in the endpoint-summary</strong>. If the information is added as a HTML table it can be included in the report generated, but it can not if it is attached.
description: EU; DOCX; pesticides.peerreview@efsa.europa.eu
DOI: 10.5281/zenodo.4557333
title: IUCLID templates for PPP Risk Assessment - Template 5.3 - Template summary table integrating experimental evidence on genotoxicity for metabolites

description: This word file contains the <strong>template for a summary table integrating experimental evidence on genotoxicity for metabolites</strong>. The filled-in template shall be uploaded in Attached (sanitised) documents for publication <strong>under 5.4 Genotoxicity testing-endpoint summary</strong> or alternatively by filling in an HTML table <strong>in the description of key information in the endpoint-summary</strong>. If the information is added as a HTML table it can be included in the report generated, but it can not if it is attached.
description: EU; DOCX; pesticides.peerreview@efsa.europa.eu
DOI: 10.6084/m9.figshare.13584986
title: Compilation of longitudinal microbiota data and hospitalome from hematopoietic cell transplantation patients

description: This dataset contains key characteristics about the data described in the Data Descriptor Compilation of longitudinal microbiota data and hospitalome from hematopoietic cell transplantation patients. <br> Contents: <br> 1. human readable metadata summary table in CSV format 2. machine readable metadata file in JSON format
DOI: 10.6084/m9.figshare.14113592
title: FUG members.sav

description: This data is a section of the larger dataset on a forestry project conducted in Mt Elgon. It shows household forest user group membership.
DOI: 10.6084/m9.figshare.14113592.v1
title: FUG members.sav

description: This data is a section of the larger dataset on a forestry project conducted in Mt Elgon. It shows household forest user group membership.
DOI: 10.5063/x34vvx
title: TEste3

description: TEste3
DOI: 10.14457/tu.the.2020.8
title: Rainfall forecasting modelling using machine learning approach

description: Rainfall forecast is essential for water resources planning and management. Various approaches for forecasting have been developed; however, the accuracy of the forecast is still not satisfied for real engineering practice. This study aims to investigate the capability of the machine learning approach in the forecasting of monthly rainfall by using Deep Learning Neural Network (DNN). Ping river basin, situated in the northern part of Thailand, was selected as a study area due to its availability of long time series of rainfall data. Six rainfall stations, distributed over the river basin, were selected for analysis using monthly rainfall from 1975 to 2018. Based on previous studies in this area, it has been revealed that 24 Large Atmospheric Variables (LAV), used as predictors in the DNN model, were correlated with monthly rainfall over the Ping river basin. The result of the first simulation using all 24 LAV during the validation period (2009-2018) in predicting monthly rainfall for 6 rainfall stations for one year ahead indicates that DNN is capable of forecasting with an accuracy of the forecast from 58-72%. Further improvement of the forecast was also conducted by the input selection technique resulting in a reduction of input LAV from 24 to 13 LAV. The second simulation of DNN with the input selection technique revealed that DNN provided better accuracy of the forecast for one year ahead with the stochastic efficiency of the forecast from 70-78%.
DOI: 10.5281/zenodo.4557367
title: IUCLID templates for PPP Risk Assessment - Template 1.1 - Template for presentation the assessment for the equivalence of batches

description: This word file contains the<strong> template for presentation the assessment for the equivalence of batches</strong>, replacing the Appendix J of the EFSA administrative guidance on submission of dossiers and assessment reports for the peer‐review of pesticide active substances (EFSA, 2019; doi:10.2903/sp.efsa.2019.EN-1612). The filled-in template shall be <strong>included in Document J </strong>which can be <strong>uploaded in the “method of manufacture” document (Section 1.8) of IUCLID</strong>.
description: EU; DOCX; pesticides.peerreview@efsa.europa.eu
description: {"references": ["European Food Safety Authority 2019. Administrative guidance on submission of dossiers and assessment reports for the peer\u2010review of pesticide active substances, EFSA supporting publication 2019: 16( 4): EN\u20101612. 49 pp. doi: 10.2903/sp.efsa.2019.EN\u20101612"]}
DOI: 10.5281/zenodo.4557366
title: IUCLID templates for PPP Risk Assessment - Template 1.1 - Template for presentation the assessment for the equivalence of batches

description: This word file contains the<strong> template for presentation the assessment for the equivalence of batches</strong>, replacing the Appendix J of the EFSA administrative guidance on submission of dossiers and assessment reports for the peer‐review of pesticide active substances (EFSA, 2019; doi:10.2903/sp.efsa.2019.EN-1612). The filled-in template shall be <strong>included in Document J </strong>which can be <strong>uploaded in the “method of manufacture” document (Section 1.8) of IUCLID</strong>.
description: EU; DOCX; pesticides.peerreview@efsa.europa.eu
description: {"references": ["European Food Safety Authority 2019. Administrative guidance on submission of dossiers and assessment reports for the peer\u2010review of pesticide active substances, EFSA supporting publication 2019: 16( 4): EN\u20101612. 49 pp. doi: 10.2903/sp.efsa.2019.EN\u20101612"]}
DOI: 10.5281/zenodo.4560402
title: Gut Vascular Barrier impairment leads to intestinal bacteria dissemination and colorectal cancer metastasis to liver

description: Code imaging related to<strong> Gut Vascular Barrier impairment leads to intestinal bacteria dissemination and colorectal cancer metastasis to liver</strong>
DOI: 10.6084/m9.figshare.14113619
title: SupplData.zip

description: Data sets and Matlab codes for manuscript titled:"Rolling balance board of adjustable geometry as a tool to assess balancing skill and to estimate reaction time delay" submitted to the Journal of the Royal Society Interface under submission number rsif-2020-0956.R2.
DOI: 10.5066/p9vpfxqr
title: Data used to develop a probabilistic assessment of tephra-fall hazards at Hanford, Washington

description: Data in this data release contain Model input and output for simulations used to estimate the amount of tephra that could fall on the Hanford nuclear waste repository. The results of that study were written up in the report: Mastin, L.G., Van Eaton, A.E., and Schwaiger, H.F., 2020 A Probabilistic Assessment of Tephra-Fall Hazards at Hanford, Washington, from a Future Eruption of Mount St. Helens, U.S. Geological Survey Open-File Report 2020-XXXX, 54 pp. That study cites supplementary tables and files, which are included in this data release. The supplementary data are contained in three zip files: 1) Main_report_supplementary_tables.zip contains the supplementary tables cited in the main report, along with a readme file. 2) Appendix_A_supplementary_files.zip contains the supplementary files cited in Appendix A. 3) Appendix_B_supplementary_tables.zip contains supplementary tables cited in Appendix B.
DOI: 10.48493/jyvf-5a27
title: ARCHIPELAGO human stable isotope database
DOI: 10.5281/zenodo.4557312
title: IUCLID templates for PPP Risk Assessment - Template 5.2 - Template for a summary assessment report of a QSAR

description: The word file "Template 5.2" contains the <strong>template for a summary assessment report of a QSAR</strong>. The filled-in template shall be uploaded in Attached (sanitised) documents for publication <strong>in the relevant endpoint study record</strong>. The word file "example" provides an <strong>example </strong>of a summary assessment report of a QSAR for genotoxicity.
description: EU; DOCX; pesticides.peerreview@efsa.europa.eu
DOI: 10.5281/zenodo.4557311
title: IUCLID templates for PPP Risk Assessment - Template 5.2 - Template for a summary assessment report of a QSAR

description: The word file "Template 5.2" contains the <strong>template for a summary assessment report of a QSAR</strong>. The filled-in template shall be uploaded in Attached (sanitised) documents for publication <strong>in the relevant endpoint study record</strong>. The word file "example" provides an <strong>example </strong>of a summary assessment report of a QSAR for genotoxicity.
description: EU; DOCX; pesticides.peerreview@efsa.europa.eu
DOI: 10.5281/zenodo.4557275
title: IUCLID templates for PPP Risk Assessment - Template 5.1 - Template for presentation of results in tabular format for mammalian toxicology studies

description: This word file contains the template for <strong>presentation of results in tabular format for mammalian toxicology studies</strong>, replacing the Appendix F of the EFSA administrative guidance on submission of dossiers and assessment reports for the peer‐review of pesticide active substances (EFSA, 2019; doi:10.2903/sp.efsa.2019.EN-1612). <br> The filled-in template shall be used when compiling HTML tables or alternatively be uploaded in Attached (sanitised) documents for publication <strong>in the relevant endpoint study record</strong>. If the information is added as a HTML table it can be included in the report generated, but it can not if it is attached.
description: EU; DOCX; pesticides.peerreview@efsa.europa.eu
description: {"references": ["European Food Safety Authority 2019. Administrative guidance on submission of dossiers and assessment reports for the peer\u2010review of pesticide active substances, EFSA supporting publication 2019: 16( 4): EN\u20101612. 49 pp. doi: 10.2903/sp.efsa.2019.EN\u20101612"]}
DOI: 10.5281/zenodo.4557274
title: IUCLID templates for PPP Risk Assessment - Template 5.1 - Template for presentation of results in tabular format for mammalian toxicology studies

description: This word file contains the template for <strong>presentation of results in tabular format for mammalian toxicology studies</strong>, replacing the Appendix F of the EFSA administrative guidance on submission of dossiers and assessment reports for the peer‐review of pesticide active substances (EFSA, 2019; doi:10.2903/sp.efsa.2019.EN-1612). <br> The filled-in template shall be used when compiling HTML tables or alternatively be uploaded in Attached (sanitised) documents for publication <strong>in the relevant endpoint study record</strong>. If the information is added as a HTML table it can be included in the report generated, but it can not if it is attached.
description: EU; DOCX; pesticides.peerreview@efsa.europa.eu
description: {"references": ["European Food Safety Authority 2019. Administrative guidance on submission of dossiers and assessment reports for the peer\u2010review of pesticide active substances, EFSA supporting publication 2019: 16( 4): EN\u20101612. 49 pp. doi: 10.2903/sp.efsa.2019.EN\u20101612"]}