cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q21z449s
title: BindingDB Entry 50028493: Role of the hydrogen bonding heteroatom-Lys53 interaction between the p38alpha mitogen-activated protein (MAP) kinase and pyridinyl-substituted 5-membered heterocyclic ring inhibitors.

description: Small molecule binding data for protein Mitogen-activated protein kinase 14, Uniprot Q16539
DOI: 10.7270/q2251j73
title: BindingDB Entry 50030711: Novel cyclic-imide peptidomimetics as aminopeptidase N inhibitors. Design, chemistry and activity evaluation. Part I.

description: Small molecule binding data for protein Aminopeptidase N, Uniprot P15145
DOI: 10.7270/q23b5zxk
title: BindingDB Entry 50026628: N-Acyl-3-amino-5H-furanone derivatives as new inhibitors of LuxR-dependent quorum sensing: Synthesis, biological evaluation and binding mode study.

description: Small molecule binding data for protein Transcriptional activator protein luxR, Uniprot P12746
DOI: 10.7270/q2542nks
title: BindingDB Entry 50029682: TBA

description: Small molecule binding data for protein Dopamine beta-hydroxylase, Uniprot P15101
DOI: 10.7270/q25q4w0p
title: BindingDB Entry 50028492: Fluorinated isatin derivatives. Part 1: synthesis of new N-substituted (S)-5-[1-(2-methoxymethylpyrrolidinyl)sulfonyl]isatins as potent caspase-3 and -7 inhibitors.

description: Small molecule binding data for protein Caspase-3 and Caspase-7, Uniprot P42574 and P55210
DOI: 10.7270/q25x290z
title: BindingDB Entry 50030710: Discovery of potential ZAP-70 kinase inhibitors: pharmacophore design, database screening and docking studies.

description: Small molecule binding data for protein Tyrosine-protein kinase ZAP-70, Uniprot P43403
DOI: 10.7270/q270818t
title: BindingDB Entry 50026627: 4-(1,3-Thiazol-2-yl)morpholine derivatives as inhibitors of phosphoinositide 3-kinase.

description: Small molecule binding data for protein PI3-kinase subunit alpha, PI3-kinase subunit beta, PI3-kinase subunit delta, and PI3-kinase subunit gamma, Uniprot O00329, P42336, P42338, and P48736
DOI: 10.7270/q28s4pwg
title: BindingDB Entry 50029681: TBA

description: Small molecule binding data for protein EDNRA, Uniprot P25101
DOI: 10.7270/q29g5mq0
title: BindingDB Entry 50028491: Design, synthesis and SAR studies of tripeptide analogs with the scaffold 3-phenylpropane-1,2-diamine as aminopeptidase N/CD13 inhibitors.

description: Small molecule binding data for protein Aminopeptidase N, Uniprot P15145
DOI: 10.7270/q29p31q8
title: BindingDB Entry 50030709: Univalent and bivalent ligands of butorphan: characteristics of the linking chain determine the affinity and potency of such opioid ligands.

description: Small molecule binding data for protein Delta-type opioid receptor, Kappa-type opioid receptor, and Mu-type opioid receptor, Uniprot P35372, P41143, and P41145
DOI: 10.7270/q29s1qvm
title: BindingDB Entry 50026641: Substituted 6-phenyl-2-naphthols. Potent and selective nonsteroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 1 (17beta-HSD1): design, synthesis, biological evaluation, and pharmacokinetics.

description: Small molecule binding data for protein Estradiol 17-beta-dehydrogenase 1 (17beta-HSD1) and Estradiol 17-beta-dehydrogenase 2, Uniprot P14061 and P37059
DOI: 10.7270/q2br8s0v
title: BindingDB Entry 50026623: Structure-activity relationship study of bone morphogenetic protein (BMP) signaling inhibitors.

description: Small molecule binding data for protein Bone morphogenetic protein 4, Uniprot P12644
DOI: 10.7270/q2dj5fkr
title: BindingDB Entry 50029679: TBA

description: Small molecule binding data for protein Epidermal growth factor receptor, VEGF-receptor 2 and tyrosine-protein kinase SRC, and cAMP-dependent protein kinase (PKA), Uniprot P00533, P12931, P17612, P22612, and P22694
DOI: 10.7270/q2f76cg5
title: BindingDB Entry 50028489: Design and synthesis of isoform-selective phospholipase D (PLD) inhibitors. Part II. Identification of the 1,3,8-triazaspiro[4,5]decan-4-one privileged structure that engenders PLD2 selectivity.

description: Small molecule binding data for protein Phospholipase D (PLD) and Phospholipase D2 (PLD2), Uniprot O14939 and Q13393
DOI: 10.7270/q2ff3sfm
title: BindingDB Entry 50030708: Probes for narcotic receptor mediated phenomena. 39. Enantiomeric N-substituted benzofuro[2,3-c]pyridin-6-ols: synthesis and topological relationship to oxide-bridged phenylmorphans.

description: Small molecule binding data for protein Delta-type opioid receptor, Kappa-type opioid receptor, and Mu-type opioid receptor, Uniprot P35372, P41143, and P41145
DOI: 10.7270/q2fj2gkb
title: BindingDB Entry 50026635: Synthesis and evaluation of pyrazolo[3,4-b]pyridines and its structural analogues as TNF-alpha and IL-6 inhibitors.

description: Small molecule binding data for protein Cyclin-dependent kinase 1, Cyclin-dependent kinase 2, and Mitogen-activated protein kinase 14, Uniprot P06493, P24941, and Q16539
DOI: 10.7270/q2j966bx
title: BindingDB Entry 50029678: TBA

description: Small molecule binding data for protein Cysteinyl leukotriene receptor 1 and Leukotriene B4 receptor, Uniprot Q15722 and Q2NNR5
DOI: 10.7270/q2k0745f
title: BindingDB Entry 50028486: Synthesis, activity and molecular modeling of a new series of chromones as low molecular weight protein tyrosine phosphatase inhibitors.

description: Small molecule binding data for protein Low molecular weight phosphotyrosine protein phosphatase (LMWPTP) and Protein-tyrosine phosphatase 1B, Uniprot P18031 and P24666
DOI: 10.7270/q2k64j5b
title: BindingDB Entry 50030707: Discovery of dermorphin-based affinity labels with subnanomolar affinity for mu opioid receptors.

description: Small molecule binding data for protein Delta-type opioid receptor, Mu-type opioid receptor, Nociceptin/mu opioid receptor, Opioid receptors; mu & delta, and mu/kappa opioid receptor, Uniprot P33533, P33535, P35372, P41143, and P97266
DOI: 10.7270/q2m908gw
title: BindingDB Entry 50026618: N-(thiazol-2-yl)-2-thiophene carboxamide derivatives as Abl inhibitors identified by a pharmacophore-based database screening of commercially available compounds.

description: Small molecule binding data for protein Tyrosine-protein kinase ABL1, Uniprot P00519
DOI: 10.7270/q2pr7vvm
title: BindingDB Entry 50028485: Argifin; efficient solid phase total synthesis and evaluation of analogues of acyclic peptide.

description: Small molecule binding data for protein Chitinase, Chitinase A, and Chitinase C1, Uniprot P07254 and P11797
DOI: 10.7270/q2pz58wb
title: BindingDB Entry 50030706: Neglected tropical diseases: multi-target-directed ligands in the search for novel lead candidates against Trypanosoma and Leishmania.

description: Small molecule binding data for protein Cruzipain and Trypanothione reductase, Uniprot P25779 and P28593
DOI: 10.7270/q2q2401s
title: BindingDB Entry 50026632: N-Benzyl-N-(pyrrolidin-3-yl)carboxamides as a new class of selective dual serotonin/noradrenaline reuptake inhibitors.

description: Small molecule binding data for protein Cytochrome P450 2D6 (2D6), Cytochrome P450 3A, Serotonin and norepinephrine transporters (SERT/NET), Sodium-dependent dopamine transporter, Sodium-dependent noradrenaline transporter, and Voltage-gated potassium channel, Uniprot P08684, P10635, P23975, P31645, Q01959, and Q12809
DOI: 10.7270/q2r2116m
title: BindingDB Entry 50026616: Novel inhibitors of anthrax edema factor.

description: Small molecule binding data for protein Calmodulin-sensitive adenylate cyclase, Uniprot P40136
DOI: 10.7270/q2rv0npw
title: BindingDB Entry 50029689: TBA

description: Small molecule binding data for protein Cholesterol esterase, Uniprot P30122
DOI: 10.7270/q2sj1kgz
title: BindingDB Entry 50028496: Design and structural analysis of novel pharmacophores for potent and selective peroxisome proliferator-activated receptor gamma agonists.

description: Small molecule binding data for protein Peroxisome proliferator-activated receptor, Peroxisome proliferator-activated receptor alpha (PPAR alpha), and Peroxisome proliferator-activated receptor delta (PPAR delta), Uniprot P37231, Q03181, and Q07869
DOI: 10.7270/q2sq90f7
title: BindingDB Entry 50030714: Synthesis and evaluation of a full-agonist orvinol for PET-imaging of opioid receptors: [11C]PEO.

description: Small molecule binding data for protein Delta-type opioid receptor, Kappa-type opioid receptor, and Mu-type opioid receptor, Uniprot P35372, P41143, and P41145
DOI: 10.7270/q2tt4qrd
title: BindingDB Entry 50026631: Synthesis and evaluation of alpha,alpha'-disubstituted phenylacetate derivatives for T-type calcium channel blockers.

description: Small molecule binding data for protein Voltage-gated T-type calcium channel and Voltage-gated potassium channel, Uniprot O43497 and Q12809
DOI: 10.7270/q2x63mvv
title: BindingDB Entry 50028494: Pyrido[2,3-e]-1,2,4-triazolo[4,3-a]pyrazin-1-one as a new scaffold to develop potent and selective human A3 adenosine receptor antagonists. Synthesis, pharmacological evaluation, and ligand-receptor modeling studies.

description: Small molecule binding data for protein Adenosine A1 receptor, Adenosine receptor A1, Adenosine receptor A2a, and Adenosine receptor A3, Uniprot P0DMS8, P25099, P28190, P29274, and P30542
DOI: 10.7270/q2zk5gg4
title: BindingDB Entry 50026629: Discovery of triazolinone non-nucleoside inhibitors of HIV reverse transcriptase.

description: Small molecule binding data for protein Cytochrome P450 3A, Uniprot P08684
DOI: 10.7270/q20c4vr4
title: BindingDB Entry 50029696: TBA

description: Small molecule binding data for protein Cyclooxygenase and Cyclooxygenase-1 (COX-1), Uniprot P23219 and P35354
DOI: 10.7270/q20z735d
title: BindingDB Entry 50028508: A new class of 5-HT2B antagonists possesses favorable potency, selectivity, and rat pharmacokinetic properties.

description: Small molecule binding data for protein Serotonin receptor (2b and 2c), Uniprot P41595
DOI: 10.7270/q2154h45
title: BindingDB Entry 50030720: Amplification of the inhibitory activity of miglitol by monofluorination.

description: Small molecule binding data for protein α-glucosidase, Uniprot P53051
DOI: 10.7270/q22b8xv3
title: BindingDB Entry 50026643: Slow self-activation enhances the potency of viridin prodrugs.

description: Small molecule binding data for protein PI3-kinase subunit alpha, Uniprot P42336
DOI: 10.7270/q2445mgv
title: BindingDB Entry 50029695: TBA

description: Small molecule binding data for protein Integrin alpha-IIb/beta-3, Uniprot P05106 and P08514
DOI: 10.7270/q24q7tvw
title: BindingDB Entry 50028506: The identification of novel PLC-gamma inhibitors using virtual high throughput screening.

description: Small molecule binding data for protein Phospholipase C-gamma-2, Uniprot P16885
DOI: 10.7270/q24x57v5
title: BindingDB Entry 50030719: O-Spiro C-aryl glucosides as novel sodium-dependent glucose co-transporter 2 (SGLT2) inhibitors.

description: Small molecule binding data for protein Sodium/glucose cotransporter 1 (SGLT1) and Sodium/glucose cotransporter 2 (SGLT2), Uniprot P13866 and P31639
DOI: 10.7270/q2542nf0
title: BindingDB Entry 50026669: Synthesis and evaluation of heteroaryl-ketone derivatives as a novel class of VEGFR-2 inhibitors.

description: Small molecule binding data for protein Vascular endothelial growth factor receptor and Vascular endothelial growth factor receptor 2, Uniprot L7RSL3, P17948, and P35968
DOI: 10.7270/q2639pjc
title: BindingDB Entry 50026642: Identification and validation of human DNA ligase inhibitors using computer-aided drug design.

description: Small molecule binding data for protein DNA Ligase I, Uniprot P18858
DOI: 10.7270/q27w6c5t
title: BindingDB Entry 50029694: TBA

description: Small molecule binding data for protein Acetylcholinesterase, Uniprot P23795
DOI: 10.7270/q28g8kkm
title: BindingDB Entry 50028502: 5,6-Diarylanthranilo-1,3-dinitriles as a new class of antihyperglycemic agents.

description: Small molecule binding data for protein Glucose-6-phosphatase and Protein-tyrosine phosphatase 1B, Uniprot P18031 and P35575
DOI: 10.7270/q28p60jf
title: BindingDB Entry 50030718: Design, synthesis, screening, and molecular modeling study of a new series of ROS1 receptor tyrosine kinase inhibitors.

description: Small molecule binding data for protein Proto-oncogene tyrosine-protein kinase ROS, Uniprot P08922
DOI: 10.7270/q28w3d4z
title: BindingDB Entry 50026665: Design and optimization of potent, selective antagonists of Oxytocin.

description: Small molecule binding data for protein Oxytocin receptor, Vasopressin V1a receptor (V1a), and Vasopressin V2 receptor (V2), Uniprot P30518, P30559, and P37288
DOI: 10.7270/q2cj8dgt
title: BindingDB Entry 50029692: TBA

description: Small molecule binding data for protein CCKBR and Cholecystokinin receptor, Uniprot P30551 and P30553
DOI: 10.7270/q2d79b9b
title: BindingDB Entry 50028501: Discovery and structure-activity study of a novel benzoxaborole anti-inflammatory agent (AN2728) for the potential topical treatment of psoriasis and atopic dermatitis.

description: Small molecule binding data for protein Phosphodiesterase 1A (PDE1A) and Phosphodiesterase 7, Uniprot P54750 and Q13946
DOI: 10.7270/q2df6r8s
title: BindingDB Entry 50030717: Kojic acid-amino acid conjugates as tyrosinase inhibitors.

description: Small molecule binding data for protein Tyrosinase, Uniprot O42713
DOI: 10.7270/q2dn44v8
title: BindingDB Entry 50026664: Exploration of a fundamental substituent effect of alpha-ketoheterocycle enzyme inhibitors: Potent and selective inhibitors of fatty acid amide hydrolase.

description: Small molecule binding data for protein Acyl-CoA: cholesterol acyltransferase (ACAT), Anandamide amidohydrolase, and Neutral cholesterol ester hydrolase 1, Uniprot P23141, P97612, and Q6PIU2
DOI: 10.7270/q2gb2418
title: BindingDB Entry 50029701: TBA

description: Small molecule binding data for protein Human immunodeficiency virus type 1 protease
DOI: 10.7270/q2h99553
title: BindingDB Entry 50029691: TBA

description: Small molecule binding data for protein Cholecystokinin receptor, Uniprot P30551, P30553, and P32238
DOI: 10.7270/q2j10322
title: BindingDB Entry 50028499: Discovery of potent non-urea inhibitors of soluble epoxide hydrolase.

description: Small molecule binding data for protein Epoxide hydratase, Uniprot P34913
DOI: 10.7270/q2j67h0h
title: BindingDB Entry 50030716: Synthesis and SAR of 1,4,5,6-tetrahydropyridazines as potent cannabinoid CB1 receptor antagonists.

description: Small molecule binding data for protein Cannabinoid receptor 1 and Cannabinoid receptor 2, Uniprot P21554 and P34972
DOI: 10.7270/q2j96664
title: BindingDB Entry 50026658: (9S)-9-(2-hydroxy-4,4-dimethyl-6-oxo-1-cyclohexen-1-yl)-3,3-dimethyl-2,3,4,9-tetrahydro-1H-xanthen-1-one, a selective and orally active neuropeptide Y Y5 receptor antagonist.

description: Small molecule binding data for protein Neuropeptide Y receptor type 1, Neuropeptide Y receptor type 2, Neuropeptide Y receptor type 5 ( NPY Y5), and PPYR1, Uniprot P25929, P49146, P50391, and Q15761
DOI: 10.7270/q2k93792
title: BindingDB Entry 50026634: Design and synthesis of novel oxazole containing 1,3-dioxane-2-carboxylic acid derivatives as PPAR alpha/gamma dual agonists.

description: Small molecule binding data for protein Peroxisome proliferator-activated receptor and Peroxisome proliferator-activated receptor alpha (PPAR alpha), Uniprot P37231 and Q07869
DOI: 10.7270/q2ms3spr
title: BindingDB Entry 50028519: Synthesis and anti-inflammatory properties of 1alpha,25-dihydroxy-16-ene-20-cyclopropyl-24-oxo-vitamin D3, a hypocalcemic, stable metabolite of 1alpha,25-dihydroxy-16-ene-20-cyclopropyl-vitamin D3.

description: Small molecule binding data for protein Vitamin D receptor, Uniprot P11473
DOI: 10.7270/q2n29wxg
title: BindingDB Entry 50029690: TBA

description: Small molecule binding data for protein Acyl coenzyme A:cholesterol acyltransferase 1, Acyl-CoA:cholesterol acyltransferase, and Sterol O-acyltransferase, Soat, Uniprot O70536 and P35610
DOI: 10.7270/q2ns0tsp
title: BindingDB Entry 50028498: Design of chimeric histone deacetylase- and tyrosine kinase-inhibitors: a series of imatinib hybrides as potent inhibitors of wild-type and mutant BCR-ABL, PDGF-Rbeta, and histone deacetylases.

description: Small molecule binding data for protein Histone deacetylase, Histone deacetylase 1, Platelet-derived growth factor receptor beta, Tyrosine-protein kinase ABL1, and Vascular endothelial growth factor receptor 2, Uniprot A0A024QZ26, P00519, P09619, P35968, Q13547, and Q9UBN7
DOI: 10.7270/q2nz87qh
title: BindingDB Entry 50030715: Diphenylmethylene hydroxamic acids as selective class IIa histone deacetylase inhibitors.

description: Small molecule binding data for protein Histone deacetylase, Histone deacetylase 1, Histone deacetylase 1/3/5/8, Histone deacetylase 4, Histone deacetylase 7 (HDAC7), and Histone deacetylase 8, Uniprot A0A024QZ26, P56524, Q13547, Q8WUI4, Q92769, Q9BY41, Q9UBN7, and Q9UQL6
DOI: 10.7270/q2p26xx2
title: BindingDB Entry 50026653: Structure-activity relationship studies on vitamin D lactam derivatives as vitamin D receptor antagonist.

description: Small molecule binding data for protein Vitamin D receptor, Uniprot P11473
DOI: 10.7270/q2qv3mgm
title: BindingDB Entry 50029699: TBA

description: Small molecule binding data for protein Human immunodeficiency virus type 1 protease
DOI: 10.7270/q2rr1z91
title: BindingDB Entry 50030722: The identification of beta-hydroxy carboxylic acids as selective MMP-12 inhibitors.

description: Small molecule binding data for protein ADAM17, Angiotensin-converting enzyme, Collagenase, Matrix metalloproteinase-1 (MMP1), Matrix metalloproteinase-12 (MMP12), Matrix metalloproteinase-14 (MMP14), Matrix metalloproteinase-7 (MMP7), and Stromelysin-1, Uniprot P03956, P08253, P08254, P09237, P12821, P14780, P39900, P45452, P50281, and P78536
DOI: 10.7270/q2st7png
title: BindingDB Entry 50026650: Discovery of piperidine-aryl urea-based stearoyl-CoA desaturase 1 inhibitors.

description: Small molecule binding data for protein Acyl-CoA desaturase 1 and Voltage-gated potassium channel, Uniprot P13516 and Q12809
DOI: 10.7270/q2vm4c7s
title: BindingDB Entry 50029697: TBA

description: Small molecule binding data for protein 12-Lipoxygenase (12-LOX), Arachidonate 15-lipoxygenase, and Arachidonate 5-lipoxygenase, Uniprot P12527, P16050, and P18054
DOI: 10.7270/q2w9593r
title: BindingDB Entry 50028509: Discovery of potent and selective DP1 receptor antagonists in the azaindole series.

description: Small molecule binding data for protein G protein-coupled receptor 44, Prostaglandin E2 receptor, Prostaglandin E2 receptor EP1 subtype (EP1), Prostaglandin E2 receptor EP2 subtype (EP2), Prostaglandin E2 receptor EP4 subtype (EP4), Prostanoid DP receptor, Prostanoid FP receptor, Prostanoid IP receptor, and Prostanoid TP receptor, Uniprot P21731, P34995, P35408, P43088, P43115, P43116, P43119, Q13258, and Q9Y5Y4
DOI: 10.7270/q2wh2q1r
title: BindingDB Entry 50030721: Identification of a cell-active non-peptide sirtuin inhibitor containing N-thioacetyl lysine.

description: Small molecule binding data for protein NAD-Dependent Deacetylase Sirtuin-1, NAD-dependent deacetylase sirtuin 2, and NAD-dependent protein deacetylase sirtuin-3 (SIRT3), Uniprot Q8IXJ6, Q96EB6, and Q9NTG7
DOI: 10.7270/q2wm1ddm
title: BindingDB Entry 50029684: TBA

description: Small molecule binding data for protein COX-1 and Prostaglandin G/H synthase (cyclooxygenase), Uniprot P05979 and Q63921
DOI: 10.7270/q2xd11rs
title: BindingDB Entry 50030712: Reactivity of isothiazolones and isothiazolone-1-oxides in the inhibition of the PCAF histone acetyltransferase.

description: Small molecule binding data for protein Histone acetyltransferase PCAF, Uniprot Q92831
DOI: 10.7270/q2xk8fc6
title: BindingDB Entry 50026649: Discovery and optimization of pyridazinone non-nucleoside inhibitors of HIV-1 reverse transcriptase.

description: Small molecule binding data for protein Cytochrome P450 1A, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), and Cytochrome P450 3A, Uniprot P05177, P08684, P10635, P11712, and P33261
DOI: 10.7270/q2028rf8
title: BindingDB Entry 50028528: 1-Sulfonyl-4-acylpiperazines as selective cannabinoid-1 receptor (CB1R) inverse agonists for the treatment of obesity.

description: Small molecule binding data for protein Cannabinoid receptor, Cannabinoid receptor 1, Cannabinoid receptor 2, Cytochrome P450 2C8, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), Cytochrome P450 3A, and Voltage-gated potassium channel, Uniprot P08684, P10632, P10635, P11712, P20272, P21554, P34972, and Q12809
DOI: 10.7270/q20865cn
title: BindingDB Entry 50030729: The discovery of tertiary-amine LXR agonists with potent cholesterol efflux activity in macrophages.

description: Small molecule binding data for protein Liver X receptor (LXR alpha AND LXR beta) and Pregnane X receptor (PXR), Uniprot O75469, P55055, and Q13133
DOI: 10.7270/q21c1wq8
title: BindingDB Entry 50026670: Structural modifications of N-arylamide oxadiazoles: Identification of N-arylpiperidine oxadiazoles as potent and selective agonists of CB2.

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 1A, Beta-1 adrenergic receptor, Cannabinoid receptor 1, Cannabinoid receptor 2, Dopamine receptor D2L/neurotensin receptor NTS1, Histamine H1 receptor, Mu-type opioid receptor, Muscarinic acetylcholine receptor M1, Neurokinin 1 receptor, Serotonin receptor (2b and 2c), Somatostatin receptor, and Voltage-gated potassium channel, Uniprot P08588, P08908, P11229, P14416, P21554, P25103, P31391, P34972, P35367, P35372, P41595, and Q12809
DOI: 10.7270/q2348kbg
title: BindingDB Entry 50029707: TBA

description: Small molecule binding data for protein Epidermal growth factor receptor, PDGFR-beta/Platelet-derived growth factor receptor alpha, Protein kinase C alpha type, Protein kinase C delta type, VEGF-receptor 2 and tyrosine-protein kinase SRC, and cAMP-dependent protein kinase (PKA), Uniprot P00533, P09619, P12931, P16234, P17252, P17612, P22612, P22694, and Q05655
DOI: 10.7270/q23r0ssz
title: BindingDB Entry 50028526: Optimisation of a series of potent, selective and orally bioavailable GlyT1 inhibitors.

description: Small molecule binding data for protein Glycine transporter 1 and Glycine transporter 2, Uniprot P48067 and Q9Y345
DOI: 10.7270/q23x86qs
title: BindingDB Entry 50030728: Synthesis and pharmacological evaluation of novel N-alkyl/aryl substituted thiazolidinone arecoline analogues as muscarinic receptor 1 agonist in Alzheimer's dementia models.

description: Small molecule binding data for protein Muscarinic acetylcholine receptor M1, Uniprot P08482
DOI: 10.7270/q26w9b2w
title: BindingDB Entry 50029706: TBA

description: Small molecule binding data for protein Protein tyrosine phosphatase SHP-2 (SHP-2), Tyrosine-protein kinase ABL1, and VEGF-receptor 2 and tyrosine-protein kinase SRC, Uniprot P00519, P12931, and Q06124
DOI: 10.7270/q27h1jg7
title: BindingDB Entry 50028525: Discovery of 4-(benzylaminomethylene)isoquinoline-1,3-(2H,4H)-diones and 4-[(pyridylmethyl)aminomethylene]isoquinoline-1,3-(2H,4H)-diones as potent and selective inhibitors of the cyclin-dependent kinase 4.

description: Small molecule binding data for protein AKT/p21CIP1, Cyclin-dependent kinase 1, Cyclin-dependent kinase 2, Cyclin-dependent kinase 4, Epidermal growth factor receptor, Histidine-tagged Rb, Inhibitor of NF-kappa-B kinase (IKK), Insulin receptor, MAP kinase-activated protein kinase 2, Mitogen-activated protein kinase kinase kinase 8, Protein kinase C theta type, Pyruvate dehydrogenase kinase isoenzyme 1 (PDK1), RAF serine/threonine protein kinase, SRC, Serine/threonine-protein kinase mTOR, Signal transducer and activator of transcription 3, VEGF-receptor 2 and tyrosine-protein kinase SRC, and Vascular endothelial growth factor receptor 2, Uniprot O14920, P00533, P06213, P06239, P06400, P06493, P07948, P11802, P12931, P15056, P24941, P31749, P35968, P40763, P41279, P42345, P49137, Q04759, and Q15118