cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q2sx6j8j
title: BindingDB Entry 50017171: Development of BRD4 inhibitors as anti-inflammatory agents and antidotes for arsenicals.

description: Small molecule binding data for protein Bromodomain-containing protein 4, Uniprot O60885
DOI: 10.7270/q2xp78zd
title: BindingDB Entry 50017169: Design, synthesis and structure-activity relationship studies of pyrido[2,3-d]pyrimidin-7-ones as potent Janus Kinase 3 (JAK3) covalent inhibitors.

description: Small molecule binding data for protein Epidermal growth factor receptor, Non-receptor tyrosine-protein kinase TYK2, Tyrosine-protein kinase BTK, Tyrosine-protein kinase JAK1, Tyrosine-protein kinase JAK2, and Tyrosine-protein kinase JAK3, Uniprot O60674, P00533, P23458, P29597, P52333, and Q06187
DOI: 10.7270/q22b933p
title: BindingDB Entry 50017167: Synthesis and evaluation of dual fatty acid amide hydrolase-monoacylglycerol lipase inhibition and antinociceptive activities of 4-methylsulfonylaniline-derived semicarbazones.

description: Small molecule binding data for protein Fatty-acid amide hydrolase 1 and Monoglyceride lipase, Uniprot O00519 and Q99685
DOI: 10.7270/q2639ts5
title: BindingDB Entry 50017163: Design, synthesis, and biological evaluation of polyphenol derivatives as DYRK1A inhibitors. The discovery of a potentially promising treatment for Multiple Sclerosis.

description: Small molecule binding data for protein Dual specificity tyrosine-phosphorylation-regulated kinase 1A, Uniprot Q13627
DOI: 10.7270/q29w0kjk
title: BindingDB Entry 50017162: Discovery of novel spiro compound as RAF kinase inhibitor with in vitro potency against KRAS mutant cancer.

description: Small molecule binding data for protein Cytochrome P450 1A2, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A4, Potassium voltage-gated channel subfamily H member 2, RAF proto-oncogene serine/threonine-protein kinase, and Serine/threonine-protein kinase B-raf, Uniprot P04049, P05177, P08684, P10635, P11712, P15056, P33261, and Q12809
DOI: 10.7270/q2fn1b89
title: BindingDB Entry 50017159: Synthesis and biological evaluation of 7H-pyrrolo [2,3-d] pyrimidine derivatives as potential p21-activated kinase 4 (PAK4) inhibitors.

description: Small molecule binding data for protein Serine/threonine-protein kinase PAK 4, Uniprot O96013
DOI: 10.7270/q2kd2301
title: BindingDB Entry 50017157: Design, synthesis, and biological evaluation of β-carboline 1,3,4-oxadiazole based hybrids as HDAC inhibitors with potential antitumor effects.

description: Small molecule binding data for protein Histone deacetylase 1, Histone deacetylase 2, Histone deacetylase 3, Histone deacetylase 6, and Histone deacetylase 8, Uniprot O15379, Q13547, Q92769, Q9BY41, and Q9UBN7
DOI: 10.7270/q2q52tph
title: BindingDB Entry 50017156: Design, synthesis, and antitumor activity evaluation of novel acyl sulfonamide spirodienones.

description: Small molecule binding data for protein 72 kDa type IV collagenase, Uniprot P08253
DOI: 10.7270/q2tx3kdx
title: BindingDB Entry 50017155: Design, synthesis, and behavioral evaluation of dual-acting compounds as phosphodiesterase type 10A (PDE10A) inhibitors and serotonin ligands targeting neuropsychiatric symptoms in dementia.

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 1A, 5-hydroxytryptamine receptor 2A, 5-hydroxytryptamine receptor 7, Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor, D(2) dopamine receptor, and cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, Uniprot P08908, P14416, P25100, P28223, P34969, P35348, P35368, and Q9Y233
DOI: 10.7270/q2zk5mqx
title: BindingDB Entry 50017154: Novel biphenyl-based scaffold as potent and selective histone deacetylase 6 (HDAC6) inhibitors: Identification, development and pharmacological evaluation.

description: Small molecule binding data for protein Histone deacetylase 1, Histone deacetylase 2, Histone deacetylase 3, Histone deacetylase 6, and Histone deacetylase 8, Uniprot O15379, Q13547, Q92769, Q9BY41, and Q9UBN7
DOI: 10.7270/q23b6455
title: BindingDB Entry 50017153: Discovery of 6,7-dihydro-5H-pyrrolo[3,4-d] pyrimidine derivatives as a new class of ATR inhibitors.

description: Small molecule binding data for protein FKBP12A/mTOR, Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform, Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha, Serine/threonine-protein kinase B-raf, and Serine/threonine-protein kinase mTOR, Uniprot O00329, O00443, P15056, P27986, P42345, and P62942
DOI: 10.7270/q2736vz0
title: BindingDB Entry 50017152: Antibacterial activity evaluation of vinyl sulfones against global predominant methicillin-resistant Staphylococcus aureus USA300.

description: Small molecule binding data for protein Sortase family protein, Uniprot Q9S446
DOI: 10.7270/q2bv7mpd
title: BindingDB Entry 50017151: Lessons Learned from Past Cyclin-Dependent Kinase Drug Discovery Efforts.

description: Small molecule binding data for protein Aurora kinase A, Aurora kinase B, Bromodomain-containing protein 4, Cyclin-A2/Cyclin-dependent kinase 2, Cyclin-dependent kinase 1, Cyclin-dependent kinase 12, Cyclin-dependent kinase 13, Cyclin-dependent kinase 14, Cyclin-dependent kinase 19, Cyclin-dependent kinase 2, Cyclin-dependent kinase 3, Cyclin-dependent kinase 4, Cyclin-dependent kinase 5, Cyclin-dependent kinase 6, Cyclin-dependent kinase 7, Cyclin-dependent kinase 8, Cyclin-dependent kinase 9, Glycogen synthase kinase-3 alpha, Glycogen synthase kinase-3 beta, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform, and Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform, Uniprot O14965, O60885, O94921, P06493, P11802, P20248, P24941, P42336, P42338, P49336, P49840, P49841, P50613, P50750, Q00526, Q00534, Q00535, Q02399, Q14004, Q96GD4, Q9BWU1, and Q9NYV4
DOI: 10.7270/q2gm8ccp
title: BindingDB Entry 50017149: Peptide-based long-acting co-agonists of GLP-1 and cholecystokinin 1 receptors as novel anti-diabesity agents.

description: Small molecule binding data for protein Cholecystokinin receptor type A, Gastrin/cholecystokinin type B receptor, and Glucagon-like peptide 1 receptor, Uniprot P32238, P32239, and P43220
DOI: 10.7270/q2mc942z
title: BindingDB Entry 50017147: Discovery and structure-activity relationships of a novel oxazolidinone class of bacterial type II topoisomerase inhibitors.

description: Small molecule binding data for protein DNA gyrase subunit A/B, DNA topoisomerase 2-alpha, and Potassium voltage-gated channel subfamily H member 2, Uniprot P0AES4, P0AES6, P11388, and Q12809
DOI: 10.7270/q2r215fd
title: BindingDB Entry 50017146: Discovery of 4-phenylindolines containing a (5-cyanopyridin-3-yl)methoxy moiety as potent inhibitors of the PD-1/PD-L1 interaction.

description: Small molecule binding data for protein Programmed cell death 1 ligand/protein 1, Uniprot Q15116 and Q9NZQ7
DOI: 10.7270/q2vt1x40
title: BindingDB Entry 50017145: Pyrizolo[1,5-a]pyrimidine derivatives of the second-generation TRK inhibitor: Design, synthesis and biological evaluation.

description: Small molecule binding data for protein ALK tyrosine kinase receptor and High affinity nerve growth factor receptor, Uniprot P04629 and Q9UM73
DOI: 10.7270/q20k2dkt
title: BindingDB Entry 50017144: Discovery of novel 2,8-diazaspiro[4.5]decan-1-one derivatives as potent RIPK1 kinase inhibitors.

description: Small molecule binding data for protein Receptor-interacting serine/threonine-protein kinase 1, Uniprot Q13546
DOI: 10.7270/q24b35b0
title: BindingDB Entry 50017138: Rationalizing the binding and α subtype selectivity of synthesized imidazodiazepines and benzodiazepines at GABAA receptors by using molecular docking studies.

description: Small molecule binding data for protein Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2, Gamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2, Gamma-aminobutyric acid receptor subunit alpha-3/beta-2/gamma-2, and Gamma-aminobutyric acid receptor subunit alpha-5/beta-2/gamma-2, Uniprot P14867, P18507, P31644, P34903, P47869, and P47870
DOI: 10.7270/q2833x2b
title: BindingDB Entry 50017137: Discovery and optimization of betulinic acid derivatives as novel potent CD73 inhibitors.

description: Small molecule binding data for protein 5'-nucleotidase, Uniprot P21589 and Q61503
DOI: 10.7270/q2cv4nsb
title: BindingDB Entry 50017134: Unraveling the Design and Discovery of c-Jun N-Terminal Kinase Inhibitors and Their Therapeutic Potential in Human Diseases.

description: Small molecule binding data for protein Leucine-rich repeat serine/threonine-protein kinase 2, Mitogen-activated protein kinase 10/8/9, Mitogen-activated protein kinase 14, Mitogen-activated protein kinase 8, and Mitogen-activated protein kinase 9, Uniprot P45983, P45984, P53779, Q16539, Q5S007, and Q91Y86
DOI: 10.7270/q2hm5dgm
title: BindingDB Entry 50017132: Design and synthesis of novel spirocyclic carboxylic acids as potent and orally bioavailable DGAT1 inhibitors and their biological evaluation.

description: Small molecule binding data for protein Acetyl-CoA acetyltransferase, mitochondrial and Diacylglycerol O-acyltransferase 1, Uniprot O75907 and P24752
DOI: 10.7270/q2n87fvh
title: BindingDB Entry 50017128: The Design and Optimization of Monomeric Multitarget Peptides for the Treatment of Multifactorial Diseases.

description: Small molecule binding data for protein Delta-type opioid receptor, Mu-type opioid receptor, and Substance-P receptor, Uniprot P25103, P35372, and P41143
DOI: 10.7270/q2s186js
title: BindingDB Entry 50017124: Main protease mutants of SARS-CoV-2 variants remain susceptible to nirmatrelvir.

description: Small molecule binding data for protein Replicase polyprotein 1ab, Uniprot P0DTD1
DOI: 10.7270/q2ws8z8t
title: BindingDB Entry 50017122: Novel D

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 1A, 5-hydroxytryptamine receptor 2A, 5-hydroxytryptamine receptor 3A, 5-hydroxytryptamine receptor 7, and D(2) dopamine receptor, Uniprot O70212, P08908, P14416, P28223, and P34969
DOI: 10.7270/q21j9ft0
title: BindingDB Entry 50017121: Human Neuraminidases: Structures and Stereoselective Inhibitors.

description: Small molecule binding data for protein Sialidase-1, Sialidase-2, Sialidase-3, and Sialidase-4, Uniprot Q8WWR8, Q99519, Q9UQ49, and Q9Y3R4
DOI: 10.7270/q25b06j8
title: BindingDB Entry 50017120: Drugging the Next Undruggable KRAS Allele-Gly12Asp.

description: Small molecule binding data for protein GTPase KRas, Uniprot P01116
DOI: 10.7270/q2930z75
title: BindingDB Entry 50017119: Advances in the Development of Nonpeptide Small Molecules Targeting Ghrelin Receptor.

description: Small molecule binding data for protein Growth hormone secretagogue receptor type 1, Uniprot Q92847
DOI: 10.7270/q2dv1pxq
title: BindingDB Entry 50017117: Discovery and characterization of benzyloxy piperidine based dopamine 4 receptor antagonists.

description: Small molecule binding data for protein D(1A) dopamine receptor, D(1B) dopamine receptor, D(3) dopamine receptor, and D(4) dopamine receptor, Uniprot P21728, P21917, P21918, and P35462
DOI: 10.7270/q2jh3r74
title: BindingDB Entry 50017111: A dual aurora and lim kinase inhibitor reduces glioblastoma proliferation and invasion.

description: Small molecule binding data for protein Aurora kinase A, Aurora kinase B, and LIM domain kinase 1, Uniprot O14965, P53667, and Q96GD4
DOI: 10.7270/q2p84gx0
title: BindingDB Entry 50017110: Discovery of pyrroledione analogs as potent transient receptor potential canonical channel 5 inhibitors.

description: Small molecule binding data for protein Short transient receptor potential channel 4 and Short transient receptor potential channel 5, Uniprot Q9UBN4 and Q9UL62
DOI: 10.7270/q2t157p5
title: BindingDB Entry 50017109: Ophiorrhines F and G, Key Biogenetic Intermediates of Ophiorrhine Alkaloids from

description: Small molecule binding data for protein Epidermal growth factor receptor, Tyrosine-protein kinase BTK, Tyrosine-protein kinase ITK/TSK, and Tyrosine-protein kinase Tec, Uniprot P00533, P42680, Q06187, and Q08881
DOI: 10.7270/q2xs60f1
title: BindingDB Entry 50017105: Tigliane Diterpenoids with Larvicidal, Antifungal, and α-Glucosidase Inhibitory Activities from

description: Small molecule binding data for protein Maltase-glucoamylase, Uniprot O43451
DOI: 10.7270/q22j6gxx
title: BindingDB Entry 50017102: Development of naringenin-O-carbamate derivatives as multi-target-directed liagnds for the treatment of Alzheimer's disease.

description: Small molecule binding data for protein Acetylcholinesterase, Carboxylic ester hydrolase, and Cholinesterase, Uniprot P06276, P22303, P37136, and Q9JKC1
DOI: 10.7270/q26977nn
title: BindingDB Entry 50017101: Structure-based design, synthesis and biological evaluation of aminopyrazines as highly potent, selective, and cellularly active allosteric SHP2 inhibitors.

description: Small molecule binding data for protein Tyrosine-protein phosphatase non-receptor type 1, Tyrosine-protein phosphatase non-receptor type 11, and Tyrosine-protein phosphatase non-receptor type 6, Uniprot P18031, P29350, and Q06124
DOI: 10.7270/q2b280bx
title: BindingDB Entry 50017099: Identification of novel xanthine oxidase inhibitors via virtual screening with enhanced characterization of molybdopterin binding groups.

description: Small molecule binding data for protein Xanthine dehydrogenase/oxidase, Uniprot P47989
DOI: 10.7270/q2fr01n5
title: BindingDB Entry 50017098: Discovery of Pyrazolo[1,5-a]pyrazin-4-ones as Potent and Brain Penetrant GluN2A-Selective Positive Allosteric Modulators Reducing AMPA Receptor Binding Activity.

description: Small molecule binding data for protein Glutamate receptor 2, Glutamate receptor ionotropic, NMDA 1/2C, Glutamate receptor ionotropic, NMDA 1/2D, and Glutamate receptor ionotropic, NMDA 2A, Uniprot O15399, P42262, Q05586, Q12879, and Q14957
DOI: 10.7270/q2kh0sb2
title: BindingDB Entry 50017097: Toll-like receptor 7 and 8 imidazoquinoline-based agonist/antagonist pairs.

description: Small molecule binding data for protein Toll-like receptor 7 and Toll-like receptor 8, Uniprot Q9NR97 and Q9NYK1
DOI: 10.7270/q2q81j37
title: BindingDB Entry 50017088: Discovery of DS-3801b, a non-macrolide GPR38 agonist with N-methylanilide structure.

description: Small molecule binding data for protein Motilin receptor, Uniprot O43193
DOI: 10.7270/q2v128v0
title: BindingDB Entry 50017084: Rational drug design to explore the structure-activity relationship (SAR) of TRK inhibitors with 2,4-diaminopyrimidine scaffold.

description: Small molecule binding data for protein ALK tyrosine kinase receptor, BDNF/NT-3 growth factors receptor, High affinity nerve growth factor receptor, NT-3 growth factor receptor, and Proto-oncogene tyrosine-protein kinase ROS, Uniprot P04629, P08922, Q16288, Q16620, and Q9UM73
DOI: 10.7270/q2zs31kd
title: BindingDB Entry 50017083: Discovery of highly potent SARS-CoV-2 M

description: Small molecule binding data for protein Replicase polyprotein 1ab, Uniprot P0DTD1
DOI: 10.7270/q23j3j18
title: BindingDB Entry 50017082: Identification and optimization of a novel series of selective PIP5K inhibitors.

description: Small molecule binding data for protein Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, Phosphatidylinositol 4-kinase alpha, Phosphatidylinositol 4-kinase beta, Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha, Phosphatidylinositol 4-phosphate 5-kinase type-1 beta, Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma, Platelet-derived growth factor receptor beta, and [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial, Uniprot O00329, O14986, O60331, P09619, P42336, P42338, P42356, P48736, Q15118, Q99755, and Q9UBF8
DOI: 10.7270/q27948q4
title: BindingDB Entry 50017080: Phenothiazine, anthraquinone and related tricyclic derivatives as inhibitors of monoamine oxidase.

description: Small molecule binding data for protein Amine oxidase [flavin-containing] A and Amine oxidase [flavin-containing] B, Uniprot P21397 and P27338
DOI: 10.7270/q2bz6b34
title: BindingDB Entry 50017079: Morphinan derivatives with an oxabicyclo[3.2.1]octane structure as dual agonists toward δ and κ opioid receptors.

description: Small molecule binding data for protein Delta-type opioid receptor, Kappa-type opioid receptor, and Mu-type opioid receptor, Uniprot P35372, P41143, and P41145
DOI: 10.7270/q2gq72s0
title: BindingDB Entry 50017078: Synthesis and biological evaluation of quinolone derivatives as transthyretin amyloidogenesis inhibitors and fluorescence sensors.

description: Small molecule binding data for protein Transthyretin, Uniprot P02766
DOI: 10.7270/q2mg7tjs
title: BindingDB Entry 50017077: Indolylarylsulfones bearing phenylboronic acid and phenylboronate ester functionalities as potent HIV‑1 non-nucleoside reverse transcriptase inhibitors.

description: Small molecule binding data for protein Reverse transcriptase/RNaseH, Uniprot Q72547
DOI: 10.7270/q2r78k8h
title: BindingDB Entry 50017075: Design, synthesis and biological evaluation of nitrofuran-1,3,4-oxadiazole hybrids as new antitubercular agents.

description: Small molecule binding data for protein Potassium voltage-gated channel subfamily H member 2, Uniprot Q12809
DOI: 10.7270/q2w09b07
title: BindingDB Entry 50017074: Quinazoline-based hydroxamic acid derivatives as dual histone methylation and deacetylation inhibitors for potential anticancer agents.

description: Small molecule binding data for protein Histone deacetylase 1, Histone deacetylase 6, and Histone-lysine N-methyltransferase EHMT1, Uniprot Q13547, Q9H9B1, and Q9UBN7
DOI: 10.7270/q20r9tgt
title: BindingDB Entry 50017072: Development of isoquinolinone derivatives as immunoproteasome inhibitors.

description: Small molecule binding data for protein Proteasome subunit beta type-1, Proteasome subunit beta type-2, and Proteasome subunit beta type-5, Uniprot P20618, P28074, and P49721
DOI: 10.7270/q24j0k5n
title: BindingDB Entry 50017071: Discovery of GCC5694A: A potent and selective sodium glucose co-transporter 2 inhibitor for the treatment of type 2 diabetes.

description: Small molecule binding data for protein Sodium/glucose cotransporter 1 and Sodium/glucose cotransporter 2, Uniprot P13866 and P31639
DOI: 10.7270/q2862mh3
title: BindingDB Entry 50017070: Towards multi-target antidiabetic agents: In vitro and in vivo evaluation of 3,5-disubstituted indolin-2-one derivatives as novel α-glucosidase inhibitors.

description: Small molecule binding data for protein Glycogen synthase kinase-3 beta, Uniprot P49841
DOI: 10.7270/q2cz3c62
title: BindingDB Entry 50017069: Dual-function antiandrogen/HDACi hybrids based on enzalutamide and entinostat.

description: Small molecule binding data for protein Androgen receptor and Histone deacetylase 1, Uniprot P10275 and Q13547
DOI: 10.7270/q2hq43zt
title: BindingDB Entry 50017068: Design, synthesis, and biological evaluation of novel (4-(1,2,4-oxadiazol-5-yl)phenyl)-2-aminoacetamide derivatives as multifunctional agents for the treatment of Alzheimer's disease.

description: Small molecule binding data for protein Acetylcholinesterase and Cholinesterase, Uniprot O42275 and P81908
DOI: 10.7270/q2ng4vqm
title: BindingDB Entry 50017067: Heat shock protein 90 (Hsp90)/Histone deacetylase (HDAC) dual inhibitors for the treatment of azoles-resistant Candida albicans.

description: Small molecule binding data for protein Heat shock protein HSP 90-alpha/90-beta and Histone deacetylase, Uniprot O15379, P07900, P08238, P56524, Q13547, Q8WUI4, Q92769, Q969S8, Q96DB2, Q9BY41, Q9UBN7, Q9UKV0, and Q9UQL6
DOI: 10.7270/q2s75mdw
title: BindingDB Entry 50017066: Discovery and optimization of cyclohexane-1,4-diamines as allosteric MALT1 inhibitors.

description: Small molecule binding data for protein Cytochrome P450 1A2, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A4, Mucosa-associated lymphoid tissue lymphoma translocation protein 1, and Potassium voltage-gated channel subfamily H member 2, Uniprot P05177, P08684, P10635, P11712, P33261, Q12809, and Q9UDY8
DOI: 10.7270/q2x06c4m
title: BindingDB Entry 50017063: Sultam based Carbonic Anhydrase VII inhibitors for the management of neuropathic pain.

description: Small molecule binding data for protein Carbonic anhydrase 1, Carbonic anhydrase 12, Carbonic anhydrase 2, Carbonic anhydrase 7, and Carbonic anhydrase 9, Uniprot O43570, P00915, P00918, P43166, and Q16790
DOI: 10.7270/q21r6vkr
title: BindingDB Entry 50017061: Construction and activity evaluation of novel benzodioxane derivatives as dual-target antifungal inhibitors.

description: Small molecule binding data for protein Lanosterol 14-alpha demethylase and Squalene epoxidase ERG1, Uniprot P10613 and Q92206
DOI: 10.7270/q25d8wwr
title: BindingDB Entry 50017060: Discovery of novel 6-hydroxybenzothiazole urea derivatives as dual Dyrk1A/α-synuclein aggregation inhibitors with neuroprotective effects.

description: Small molecule binding data for protein Alpha-synuclein, Dual specificity tyrosine-phosphorylation-regulated kinase 1A, Dual specificity tyrosine-phosphorylation-regulated kinase 1B, and Dual specificity tyrosine-phosphorylation-regulated kinase 2, Uniprot P37840, Q13627, Q92630, and Q9Y463
DOI: 10.7270/q2959nk1
title: BindingDB Entry 50017059: Identification of a selective BRD4 PROTAC with potent antiproliferative effects in AR-positive prostate cancer based on a dual BET/PLK1 inhibitor.

description: Small molecule binding data for protein Bromodomain-containing protein 4 and Serine/threonine-protein kinase PLK1, Uniprot O60885 and P53350
DOI: 10.7270/q2dz0dbf
title: BindingDB Entry 50017058: Discovery and optimization of new 6, 7-dihydroxy-1, 2, 3, 4-tetrahydroisoquinoline derivatives as potent influenza virus PA

description: Small molecule binding data for protein Polymerase acidic protein, Uniprot P03433
DOI: 10.7270/q2jq1525
title: BindingDB Entry 50017057: Exploring disordered loops in DprE1 provides a functional site to combat drug-resistance in Mycobacterium strains.

description: Small molecule binding data for protein Decaprenylphosphoryl-beta-D-ribose oxidase, Uniprot P9WJF1
DOI: 10.7270/q2pg1ws3
title: BindingDB Entry 50017056: Pyridazino-pyrrolo-quinoxalinium salts as highly potent and selective leishmanicidal agents targeting trypanothione reductase.

description: Small molecule binding data for protein Trypanothione reductase, Uniprot A4HSF7
DOI: 10.7270/q2t72nht
title: BindingDB Entry 50017055: Discovery and radiosensitization research of ursolic acid derivatives as SENP1 inhibitors.

description: Small molecule binding data for protein Sentrin-specific protease 1, Uniprot Q9P0U3
DOI: 10.7270/q2z03d63
title: BindingDB Entry 50017053: Design, synthesis, and biological evaluation of N-(3-cyano-1H-indol-5/6-yl)-6-oxo-1,6-dihydropyrimidine-4-carboxamides and 5-(6-oxo-1,6-dihydropyrimidin-2-yl)-1H-indole-3-carbonitriles as novel xanthine oxidase inhibitors.

description: Small molecule binding data for protein Xanthine dehydrogenase/oxidase, Uniprot P47989
DOI: 10.7270/q22n56bn
title: BindingDB Entry 50017052: Investigation of chalcogen bioisosteric replacement in a series of heterocyclic inhibitors of tryptophan 2,3-dioxygenase.

description: Small molecule binding data for protein Indoleamine 2,3-dioxygenase 1 and Tryptophan 2,3-dioxygenase, Uniprot P14902 and P48775
DOI: 10.7270/q26d5z1j
title: BindingDB Entry 50017051: Design, synthesis and biological evaluation of bisindole derivatives as anticancer agents against Tousled-like kinases.

description: Small molecule binding data for protein Serine/threonine-protein kinase tousled-like 2, Uniprot Q86UE8