cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.15156/bio/sh3426275.08fu
title: SH3426275.08FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15156/bio/sh3426276.08fu
title: SH3426276.08FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15156/bio/sh3426277.08fu
title: SH3426277.08FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15156/bio/sh3426278.08fu
title: SH3426278.08FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15156/bio/sh3426279.08fu
title: SH3426279.08FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15156/bio/sh3426280.08fu
title: SH3426280.08FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15156/bio/sh3426281.08fu
title: SH3426281.08FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15156/bio/sh3426282.08fu
title: SH3426282.08FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.7270/q2c53pr1
title: BindingDB Entry 50005393: Discovery of potent selective bioavailable phosphodiesterase 2 (PDE2) inhibitors active in an osteoarthritis pain model. Part II: optimization studies and demonstration of in vivo efficacy.

description: Small molecule binding data for protein 3',5'-cyclic phosphodiesterase and Homo sapiens phosphodiesterase 2A (PDE2A), Uniprot O00408, Q07343, and X5DNX5
DOI: 10.7270/q2gx4fgf
title: BindingDB Entry 50005392: Optimization of a 1,5-dihydrobenzo[b][1,4]diazepine-2,4-dione series of HIV capsid assembly inhibitors 1: addressing configurational instability through scaffold modification.

description: Small molecule binding data for protein Structural capsid protein, Uniprot Q76129
DOI: 10.7270/q23n269c
title: BindingDB Entry 50005397: Synthesis and evaluation of N-substituted nipecotic acid derivatives with an unsymmetrical bis-aromatic residue attached to a vinyl ether spacer as potential GABA uptake inhibitors.

description: Small molecule binding data for protein GABA transporter, Uniprot P23978, P31649, and P31650
DOI: 10.7270/q27d2z1q
title: BindingDB Entry 50005394: Design and synthesis of L- and D-phenylalanine derived rhodanines with novel C5-arylidenes as inhibitors of HCV NS5B polymerase.

description: Small molecule binding data for protein RNA-directed RNA polymerase, Uniprot O39930
DOI: 10.7270/q200050p
title: BindingDB Entry 50005398: Therapeutic and pharmacokinetic characterizations of an anti-amyloidogenic bis-styrylbenzene derivative for Alzheimer's disease treatment.

description: Small molecule binding data for protein Beta amyloid A4 protein, Uniprot A0A140VJC8 and P05067
DOI: 10.7270/q2v69nhf
title: BindingDB Entry 50005399: Tri-substituted imidazole analogues of SB203580 as inducers for cardiomyogenesis of human embryonic stem cells.

description: Small molecule binding data for protein p38 MAP kinase alpha/beta, Uniprot A0A024RD15 and Q16539
DOI: 10.7270/q2qf8wsq
title: BindingDB Entry 50005400: Identification of the fused bicyclic 4-amino-2-phenylpyrimidine derivatives as novel and potent PDE4 inhibitors.

description: Small molecule binding data for protein 3',5'-cyclic phosphodiesterase, Uniprot Q07343 and X5DNX5
DOI: 10.7270/q2kp852s
title: BindingDB Entry 50005401: Design, synthesis and biological evaluation of novel pyrimidine, 3-cyanopyridine and m-amino-N-phenylbenzamide based monocyclic EGFR tyrosine kinase inhibitors.

description: Small molecule binding data for protein MER intracellular domain/EGFR extracellular domain chimera and Receptor tyrosine-protein kinase erbB-2, Uniprot P00533, P04626, and X5DNK3
DOI: 10.7270/q2b56nn3
title: BindingDB Entry 50005403: Dual-acting histone deacetylase-topoisomerase I inhibitors.

description: Small molecule binding data for protein Histone deacetylase and Histone deacetylase 8, Uniprot A0A024QZ26, O15379, P56524, Q13547, Q6IT96, Q8WUI4, Q92769, Q969S8, Q96DB2, Q9BY41, Q9UBN7, Q9UKV0, and Q9UQL6
DOI: 10.7270/q2fx7dch
title: BindingDB Entry 50005402: Probes for narcotic receptor mediated phenomena. 47. Novel C4a- and N-substituted-1,2,3,4,4a,9a-hexahydrobenzofuro[2,3-c]pyridin-6-ols.

description: Small molecule binding data for protein Delta-type opioid receptor, Kappa-type opioid receptor, and Mu-type opioid receptor, Uniprot P35372, P41143, and P41145
DOI: 10.7270/q26d5wxc
title: BindingDB Entry 50005404: Synthesis and carbonic anhydrase inhibitory properties of sulfamides structurally related to dopamine.

description: Small molecule binding data for protein Carbonic anhydrase, Carbonic anhydrase V, and Carbonic anhydrases; II & IX, Uniprot A0A0S2Z3D0, A8K3J4, O43570, P00915, P00918, P35218, Q16790, Q9ULX7, V9HW21, and V9HWE3
DOI: 10.7270/q22r3vkx
title: BindingDB Entry 50005405: Selective CB2 agonists with anti-pruritic activity: discovery of potent and orally available bicyclic 2-pyridones.

description: Small molecule binding data for protein Cannabinoid receptor 1 and Cannabinoid receptor 2, Uniprot A0A024RAH7, A0A385KNU8, P21554, P34972, P47746, and S5TLS4
DOI: 10.7270/q2z03c3b
title: BindingDB Entry 50005406: Synthesis and antifungal evaluation of pentyloxyl-diphenylisoxazoloyl pneumocandins and echinocandins.

description: Small molecule binding data for protein Beta-1,3-glucan synthase, Uniprot O13383
DOI: 10.7270/q2t72mcm
title: BindingDB Entry 50005408: Effect of anchoring 4-anilidopiperidines to opioid peptides.

description: Small molecule binding data for protein Delta-type opioid receptor, Mu-type opioid receptor, Nociceptin/mu opioid receptor, and Opioid receptors; mu and delta, Uniprot A2AD37, P32300, P33535, P41143, and P97266
DOI: 10.7270/q2pg1vnw
title: BindingDB Entry 50005409: Development of cell-active non-peptidyl inhibitors of cysteine cathepsins.

description: Small molecule binding data for protein Cathepsin (B and K), Uniprot A0A024R374 and P07858
DOI: 10.7270/q2dz0c7p
title: BindingDB Entry 50005411: Design, synthesis and biological evaluation of indeno[1,2-d]thiazole derivatives as potent histone deacetylase inhibitors.

description: Small molecule binding data for protein Histone deacetylase, Uniprot A0A024QZ26, O15379, P56524, Q13547, Q6IT96, Q8WUI4, Q92769, Q969S8, Q96DB2, Q9BY41, Q9UBN7, Q9UKV0, and Q9UQL6
DOI: 10.7270/q2jq13xj
title: BindingDB Entry 50005410: Design and synthesis of novel opioid ligands with an azabicyclo[2.2.2]octane skeleton having a 7-amide side chain and their pharmacologies.

description: Small molecule binding data for protein Kappa-type opioid receptor, Opioid receptors; mu and delta, and mu/kappa opioid receptor, Uniprot A2AD37, P32300, P41144, P41145, and P42866
DOI: 10.7270/q2959mhq
title: BindingDB Entry 50005413: Design, synthesis, and initial evaluation of a high affinity positron emission tomography probe for imaging matrix metalloproteinases 2 and 9.

description: Small molecule binding data for protein Interstitial collagenase and Matrix metalloproteinase 2/9, Uniprot A0A024R6R4, P03956, P08253, and P14780
DOI: 10.7270/q25h7k58
title: BindingDB Entry 50005416: Metabolites from Microcystis aeruginosa bloom material collected at a water reservoir near Kibbutz Hafetz Haim, Israel.

description: Small molecule binding data for protein Trypsin, Uniprot P07477, P07478, P35030, and Q5NV56
DOI: 10.7270/q21r6tfj
title: BindingDB Entry 50005417: Characterization of maleimide-based glycogen synthase kinase-3 (GSK-3) inhibitors as stimulators of steroidogenesis.

description: Small molecule binding data for protein Axin-1/Glycogen synthase kinase-3 beta, Uniprot P49841 and Q6FI27
DOI: 10.7270/q2s75k77
title: BindingDB Entry 50005419: Potential of lichen secondary metabolites against Plasmodium liver stage parasites with FAS-II as the potential target.

description: Small molecule binding data for protein Enoyl-ACP Reductase (FabI), Uniprot P0AEK4
DOI: 10.7270/q2x069zj
title: BindingDB Entry 50005418: Aeruginosins from a Microcystis sp. bloom material collected in Varanasi, India.

description: Small molecule binding data for protein Trypsin, Uniprot P07477, P07478, P35030, and Q5NV56
DOI: 10.7270/q2ng4tjz
title: BindingDB Entry 50005420: Recent development of potent analogues of oxazolidinone antibacterial agents.

description: Small molecule binding data for protein Amine oxidase (flavin-containing) A, Uniprot P21397 and Q53YE7
DOI: 10.7270/q2cz3b39
title: BindingDB Entry 50005423: Identification and synthesis of N-(thiophen-2-yl) benzamide derivatives as BRAF(V600E) inhibitors.

description: Small molecule binding data for protein BRAF/CRAF, Uniprot P15056
DOI: 10.7270/q2hq42tm
title: BindingDB Entry 50005422: Inhibition of monoamine oxidase by phthalide analogues.

description: Small molecule binding data for protein Amine oxidase (flavin-containing) A, Amine oxidase [flavin-containing] B, and Monoamine oxidase, Uniprot P19643, P21396, P21397, P27338, and Q53YE7
DOI: 10.7270/q24j0j2w
title: BindingDB Entry 50005427: Dieckol, a SARS-CoV 3CL(pro) inhibitor, isolated from the edible brown algae Ecklonia cava.

description: Small molecule binding data for protein 3C-like proteinase (3CL-PRO), Uniprot A7J8L2 and P0C6X7
DOI: 10.7270/q28918s6
title: BindingDB Entry 50005425: Synthesis and structure-activity relationships of 2-amino-3-carboxy-4-phenylthiophenes as novel atypical protein kinase C inhibitors.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2 and Protein kinase C iota type/zeta type, Uniprot P40989, P41743, and Q05513
DOI: 10.7270/q20r9sbm
title: BindingDB Entry 50005429: The use of virtual screening and differential scanning fluorimetry for the rapid identification of fragments active against MEK1.

description: Small molecule binding data for protein Dual specificity mitogen-activated protein kinase kinase 1/Mitogen-activated protein kinase 1/RAF proto-oncogene serine/threonine-protein kinase, Uniprot A4QPA9 and Q02750
DOI: 10.7270/q2r78j49
title: BindingDB Entry 50005431: Caffeic acid derivatives: a new type of influenza neuraminidase inhibitors.

description: Small molecule binding data for protein Neuraminidase
DOI: 10.7270/q2w098vm
title: BindingDB Entry 50005430: A novel benzazepinone sodium channel blocker with oral efficacy in a rat model of neuropathic pain.

description: Small molecule binding data for protein Sodium channel protein type 9 subunit alpha, Uniprot Q15858
DOI: 10.7270/q2mg7sf1
title: BindingDB Entry 50005433: Development of indole/indazole-aminopyrimidines as inhibitors of c-Jun N-terminal kinase (JNK): optimization for JNK potency and physicochemical properties.

description: Small molecule binding data for protein c-Jun N-terminal kinase, JNK, Uniprot P45983, P45984, and P53779
DOI: 10.7270/q2c250cj
title: BindingDB Entry 50005437: New insight into adenosine receptors selectivity derived from a novel series of [5-substituted-4-phenyl-1,3-thiazol-2-yl] benzamides and furamides.

description: Small molecule binding data for protein Adenosine receptor A1, Adenosine receptor A2a, Adenosine receptor A3, and Adenosine receptors; A2a & A2b, Uniprot P0DMS8, P29274, P29275, P30542, and X5DNB4
DOI: 10.7270/q2gt5r3k
title: BindingDB Entry 50005436: A class of pyrrole derivatives endowed with analgesic/anti-inflammatory activity.

description: Small molecule binding data for protein Cyclooxygenase, Prostaglandin E synthase/G/H synthase 2, and Prostaglandin G/H synthase (cyclooxygenase), Uniprot P22437, P23219, P35354, Q05769, and Q543T1
DOI: 10.7270/q23j3gx3
title: BindingDB Entry 50005439: Dissecting the pharmacophore of curcumin. Which structural element is critical for which action?

description: Small molecule binding data for protein Integrase and Protease, Uniprot F2WR39,F2WR52,Q76353 and Q9YQ12
DOI: 10.7270/q27947nt
title: BindingDB Entry 50005438: Synthesis and pharmacological properties of a new hydrophilic and orally bioavailable 5-HT4 antagonist.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2 and Serotonin (5-HT) receptor, Uniprot A0A2D3FAF9, P40989, and Q13639
DOI: 10.7270/q2zs30gn
title: BindingDB Entry 50005441: Peptidomimetic modification improves cell permeation of bivalent farnesyltransferase inhibitors.

description: Small molecule binding data for protein Protein Farnesyltransferase (PFT), Uniprot A0A384MEJ5, P49354, and P49356
DOI: 10.7270/q2kk9fqz
title: BindingDB Entry 50005445: Structure-based design of β-site APP cleaving enzyme 1 (BACE1) inhibitors for the treatment of Alzheimer's disease.

description: Small molecule binding data for protein Beta-secretase (BACE), Uniprot A0A024R3D7 and P56817
DOI: 10.7270/q2q81h1x
title: BindingDB Entry 50005444: Discovery of a novel [3.2.1] benzo fused bicyclic sulfonamide-pyrazoles as potent, selective and efficacious γ-secretase inhibitors.

description: Small molecule binding data for protein Presenilin-1, Uniprot A0A024R6A3 and P49768
DOI: 10.7270/q2v127r7
title: BindingDB Entry 50005442: Inhibition of HIV-1 integrase dimerization and activity with crosslinked interfacial peptides.

description: Small molecule binding data for protein Integrase, Uniprot T1QYY3
DOI: 10.7270/q2b27z7s
title: BindingDB Entry 50005447: Exploiting drug-resistant enzymes as tools to identify thienopyrimidinone inhibitors of human immunodeficiency virus reverse transcriptase-associated ribonuclease H.

description: Small molecule binding data for protein Reverse transcriptase, Uniprot Q9WKE8
DOI: 10.7270/q2ft8pzs
title: BindingDB Entry 50005446: Orally active opioid compounds from a non-poppy source.

description: Small molecule binding data for protein Delta-type opioid receptor, Kappa-type opioid receptor, Mu-type opioid receptor, and mu/kappa opioid receptor, Uniprot P35372, P41143, P41144, P41145, and P97266
DOI: 10.7270/q26976hf
title: BindingDB Entry 50005448: Identification of potent and orally bioavailable nucleotide competing reverse transcriptase inhibitors: in vitro and in vivo optimization of a series of benzofurano[3,2-d]pyrimidin-2-one derived inhibitors.

description: Small molecule binding data for protein Reverse transcriptase, Uniprot Q9WKE8
DOI: 10.7270/q22j6fsq
title: BindingDB Entry 50005449: Synthesis and biological evaluation of 18F-labled 2-phenylindole derivatives as PET imaging probes for β-amyloid plaques.

description: Small molecule binding data for protein Beta amyloid A4 protein, Uniprot A0A140VJC8 and P05067
DOI: 10.7270/q2xs5z9f
title: BindingDB Entry 50005450: Synthesis and evaluation of 8-amino-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one derivatives as glycogen synthase kinase-3 (GSK-3) inhibitors.

description: Small molecule binding data for protein Glycogen synthase kinase-3, Uniprot A0A024R0L5, P49840, P49841, and Q6FI27
DOI: 10.7270/q2t156kd
title: BindingDB Entry 50005451: Synthesis and SAR of potent and selective tetrahydropyrazinoisoquinolinone 5-HT(2C) receptor agonists.

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 2A, 5-hydroxytryptamine receptor 2B, and 5-hydroxytryptamine receptor 2C, Uniprot P28223, P28335, and P41595
DOI: 10.7270/q2jm2dk4
title: BindingDB Entry 50005457: In vitro and in vivo evaluation of polymethylene tetraamine derivatives as NMDA receptor channel blockers.

description: Small molecule binding data for protein NR1/NR2A, Uniprot Q05586, Q12879, and Q547U9
DOI: 10.7270/q2pc359v
title: BindingDB Entry 50005455: 20(S)-Protopanaxadiol (PPD) analogues chemosensitize multidrug-resistant cancer cells to clinical anticancer drugs.

description: Small molecule binding data for protein Multidrug resistance protein 1/Multidrug resistance associated protein 1, Uniprot A4D1D2 and P08183
DOI: 10.7270/q2dv1ntz
title: BindingDB Entry 50005459: 1,4-Diaryl-substituted triazoles as cyclooxygenase-2 inhibitors: Synthesis, biological evaluation and molecular modeling studies.

description: Small molecule binding data for protein Prostaglandin E synthase/G/H synthase 2 and Prostaglandin G/H synthase (cyclooxygenase), Uniprot P05979 and P35354