DOI: 10.5061/dryad.p0c87
title: Data from: Effects of a 60 Hz magnetic field exposure up to 3000 µT on human brain activation as measured by functional magnetic resonance imaging

description: Several aspects of the human nervous system and associated motor and
 cognitive processes have been reported to be modulated by extremely
 low-frequency (ELF, &lt; 300 Hz) time-varying Magnetic Fields (MF).
 Due do their worldwide prevalence; power-line frequencies (60 Hz in North
 America) are of particular interest. Despite intense research efforts over
 the last few decades, the potential effects of 60 Hz MF still need to be
 elucidated, and the underlying mechanisms to be understood. In this study,
 we have used functional Magnetic Resonance Imaging (fMRI) to characterize
 potential changes in functional brain activation following human exposure
 to a 60 Hz MF through motor and cognitive tasks. First, pilot results
 acquired in a first set of subjects (N=9) were used to demonstrate the
 technical feasibility of using fMRI to detect subtle changes in functional
 brain activation with 60 Hz MF exposure at 1800 μT. Second, a full study
 involving a larger cohort of subjects tested brain activation during 1) a
 finger tapping task (N=20), and 2) a mental rotation task (N=21); before
 and after a one-hour, 60 Hz, 3000 μT MF exposure. The results indicate
 significant changes in task-induced functional brain activation as a
 consequence of MF exposure. However, no impact on task performance was
 found. These results illustrate the potential of using fMRI to identify
 MF-induced changes in functional brain activation, suggesting that a
 one-hour 60 Hz, 3000 μT MF exposure can modulate activity in specific
 brain regions after the end of the exposure period (i.e., residual
 effects). We discuss the possibility that MF exposure at 60 Hz, 3000 μT
 may be capable of modulating cortical excitability via a modulation of
 synaptic plasticity processes.
description: fMRI full experiment
 3000 microTesla part 1fMRI full experiment
 3000 microTesla part 1-10: MRI and fMRI DICOM images corresponding to the
 full study conducted with a 3000 microTesla exposure. These DICOM files
 have been produced by a Siemens 3T Verio (Siemens, Germany) MRI, as
 described in the paper. DICOM is a standard format for MRI images, and
 these can be analyzed with software packages such as BrainVoyager (Brain
 Innovation, The Netherlands), which we have used in the paper; or an
 open-access software package such as FSL
 (http://fsl.fmrib.ox.ac.uk/fsl/fslwiki/). The analysis procedure for the
 fMRI data is fully described in the Methods section of the paper. DICOM
 files are available for each subject pre- and post-exposure, for each of
 the two tasks presented in the paper (finger tapping and mental rotation).
 Two tasks were used in this experiment: a mental rotation task and a
 finger tapping task. The subject who have properly conducted the mental
 rotation task and have been included in the analysis are: S02, S03, S04,
 S06, S07, S09, S10, S11, S12, S13, S14, S16, S17, S18, S20, S21, S23, S24,
 S25, S27, S29. The subject who have properly conducted the finger tapping
 task and have been included in the analysis are: S03, S04, S06, S07, S08,
 S09, S10, S12, S13, S14, S16, S17, S20, S22, S23, S24, S25, S26, S27, S29.
 Please feel free to contact the authors if further guidance is
 required.fMRI full experiment
 3000 microTesla part 2fMRI full experiment
 3000 microTesla part 3fMRI full experiment
 3000 microTesla part 4fMRI full experiment
 3000 microTesla part 5fMRI full experiment
 3000 microTesla part 6fMRI full experiment
 3000 microTesla part 7fMRI full experiment
 3000 microTesla part 8fMRI full experiment
 3000 microTesla part 9fMRI full experiment
 3000 microTesla part 10fMRI_Pilot_1800_microTesla_DICOM part 1fMRI_Pilot_1800_microTesla_DICOM part 1-2: MRI and fMRI DICOM images corresponding to the pilot study conducted with a 1800 microTesla exposure These DICOM files have been produced by a Siemens 1.5T Avanto (Siemens, Germany) MRI, as described in the paper. DICOM is a standard format for MRI images, and these can be analyzed with software packages such as BrainVoyager (Brain Innovation, The Netherlands), which we have used in the paper; or an open-access software package such as FSL (http://fsl.fmrib.ox.ac.uk/fsl/fslwiki/). The analysis procedure for the fMRI data is fully described in the Methods section of the paper. DICOM files are available for each subject pre- and post-exposure, for each of the two tasks presented in the paper (finger tapping and mental rotation). Please feel free to contact the authors if further guidance is required.fMRI_Pilot_1800_microTesla_DICOM part 2