cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.8186984.v2
title: Differential requirements of protein geranylgeranylation for the virulence of human pathogenic fungi

description: Protein prenylation is a crucial post-translational modification largely mediated by two heterodimeric enzyme complexes, farnesyltransferase and geranylgeranyltransferase type-I (GGTase-I), each composed of a shared α-subunit and a unique β-subunit. GGTase-I enzymes are validated drug targets that contribute to virulence in <i>Cryptococcus neoformans</i> and to the yeast-to-hyphal transition in <i>Candida albicans</i>. Therefore, we sought to investigate the importance of the α-subunit, RamB, and the β-subunit, Cdc43, of the <i>A. fumigatus</i> GGTase-I complex to hyphal growth and virulence. Deletion of <i>cdc43</i> resulted in impaired hyphal morphogenesis and thermo-sensitivity, which was exacerbated during growth in rich media. The Δ<i>cdc43</i> mutant also displayed hypersensitivity to cell wall stress agents and to cell wall synthesis inhibitors, suggesting alterations of cell wall biosynthesis or stress signaling. In support of this, analyses of cell wall content revealed decreased amounts of β-glucan in the Δ<i>cdc43</i> strain. Despite strong <i>in vitro</i> phenotypes, the Δ<i>cdc43</i> mutant was fully virulent in two models of murine invasive aspergillosis, similar to the control strain. We further found that a strain expressing the α-subunit gene, <i>ramB</i>, from a tetracycline-inducible promoter was inviable under non-inducing <i>in vitro</i> growth conditions and was virtually avirulent in both mouse models. Lastly, virulence studies using <i>C. albicans</i> strains with tetracycline-repressible <i>RAM2</i> or <i>CDC43</i> expression revealed reduced pathogenicity associated with downregulation of either gene in a murine model of disseminated infection. Together, these findings indicate a differential requirement for protein geranylgeranylation for fungal virulence, and further inform the selection of specific prenyltransferases as promising antifungal drug targets for each pathogen.
DOI: 10.6084/m9.figshare.3761562.v1337
title: Online Labour Index: Measuring the Online Gig Economy for Policy and Research

description: Data repository for the data underlying the Online Labour Index. See http://ilabour.oii.ox.ac.uk online-labour-index/ for details.
DOI: 10.6084/m9.figshare.3761562.v1338
title: Online Labour Index: Measuring the Online Gig Economy for Policy and Research

description: Data repository for the data underlying the Online Labour Index. See http://ilabour.oii.ox.ac.uk online-labour-index/ for details.
DOI: 10.6084/m9.figshare.3761562.v1339
title: Online Labour Index: Measuring the Online Gig Economy for Policy and Research

description: Data repository for the data underlying the Online Labour Index. See http://ilabour.oii.ox.ac.uk online-labour-index/ for details.
DOI: 10.25386/genetics.11440986
title: Supplemental Material for Ianiri et al., 2020

description: Revised version of Supplemental files relatives to the manuscript GENETICS/2019/302740R1 <b>Mating-type specific ribosomal proteins control aspects of sexual reproduction in <i>Cryptococcus neoformans</i></b>
DOI: 10.25387/g3.10006634.v1
title: Supplemental Material for Miller, 2020

description: Supplemental tables for manuscript looking at DSB repair and meiotic events in D. melanogaster females unable to construct full-length SC and females heterozygous for SC mutants.
DOI: 10.25387/g3.11449542.v1
title: Supplementary Material for Kandul, 2020

description: Supplementary Figures
DOI: 10.25387/g3.10006634
title: Supplemental Material for Miller, 2020

description: Supplemental tables for manuscript looking at DSB repair and meiotic events in D. melanogaster females unable to construct full-length SC and females heterozygous for SC mutants.
DOI: 10.25386/genetics.11440986.v1
title: Supplemental Material for Ianiri et al., 2020

description: Revised version of Supplemental files relatives to the manuscript GENETICS/2019/302740R1 <b>Mating-type specific ribosomal proteins control aspects of sexual reproduction in <i>Cryptococcus neoformans</i></b>
DOI: 10.25387/g3.11449542
title: Supplementary Material for Kandul, 2020

description: Supplementary Figures
DOI: 10.25405/data.ncl.11470392
title: Transient absorption spectroscopy porphyrins and photocatalysts

description: Nanosecond transient measurements were performed with a custom laser spectrometer comprised of a Brillian Quantel laser with frequency doubled (532 nm, 330 mJ) or tripled (355 nm, 160 mJ) option, an Applied Photophysics xenon light source including a mod. 720 150 W lamp housing, a mod. 620 power controlled lamp supply and a mod. 03- 102 arc lamp pulser. Laser excitation was provided at 90° with respect to the white light probe beam. Light transmitted by the sample was focused onto the entrance slit of a SpectraKinetic monochromator (Applied photophysics). Kinetic traces were processed by means of a Agilent digital oscilloscope. A typical pulse energy of 2 mJ cm<sup>−2</sup> was used.<br>Zn and Sn refer to the metal centreme = Ph-CO2Me subsituentOH = Ph-CO2HN = pyridyl PH and POEt = Ph-PO(OEt)2<br>TEOA = 5% v/v triethanolamine added to 1:1 MeCN:H2O solutioncat = 10 equiv <b>CoNMeim </b>addedN+ = methyl pyridiniumstructures are provided in the JPEG file.<br><br>
DOI: 10.6084/m9.figshare.11472648
title: Leaf & root associated microbiomes from three Asian green's grown in an urban farm (2018)

description: Metagenome Assembled Genomes (MAG's) from three Asian green's grown in an urban farm in Singapore
DOI: 10.6084/m9.figshare.11472648.v1
title: Leaf & root associated microbiomes from three Asian green's grown in an urban farm (2018)

description: Metagenome Assembled Genomes (MAG's) from three Asian green's grown in an urban farm in Singapore
DOI: 10.6084/m9.figshare.3761562.v1344
title: Online Labour Index: Measuring the Online Gig Economy for Policy and Research

description: Data repository for the data underlying the Online Labour Index. See http://ilabour.oii.ox.ac.uk online-labour-index/ for details.
DOI: 10.6084/m9.figshare.11446692.v2
title: MOESM1 of Microbiome changes: an indicator of Parkinson’s disease?

description: Additional file 1: Table S1. Compliation of the reported findings from stool microbiome studies comparing PD patients to healthy controls. + = higher in PD patients; - = higher in controls subjects; * = p &lt; 0.05.
DOI: 10.6084/m9.figshare.3761562.v1345
title: Online Labour Index: Measuring the Online Gig Economy for Policy and Research

description: Data repository for the data underlying the Online Labour Index. See http://ilabour.oii.ox.ac.uk online-labour-index/ for details.
DOI: 10.6084/m9.figshare.11494545
title: Global Annual Urban Dynamics 1985-2015

description: <b>High spatiotemporal resolution mapping of global urban change from 1985 to 2015</b>
DOI: 10.25412/iop.11429904
title: SUPPLEMENTARY_DATA.zip

description: The interannual variability of ENSO, water availability (MIDI, SPI, scPDSI), and atmospheric CO<sub>2</sub> growth rate.
DOI: 10.6084/m9.figshare.11494545.v1
title: Global Annual Urban Dynamics 1985-2015

description: <b>High spatiotemporal resolution mapping of global urban change from 1985 to 2015</b>
DOI: 10.6084/m9.figshare.11494545.v2
title: Global Annual Urban Dynamics 1985-2015

description: <b>High spatiotemporal resolution mapping of global urban change from 1985 to 2015</b>
DOI: 10.25412/iop.11429904.v1
title: SUPPLEMENTARY_DATA.zip

description: The interannual variability of ENSO, water availability (MIDI, SPI, scPDSI), and atmospheric CO<sub>2</sub> growth rate.
DOI: 10.25405/data.ncl.11494395
title: Learning Ethics from Dementia Researchers in the Context of HCI

description: The data in this record is of qualitative discussions to gain an understanding of ethical experiences and practices in the field of HCI and dementia. These interviews took place between June and Early September 2019. The data set contains 22 anonymised interviews from diverse countries, institutions, and disciplines. These interviews range from 45 minutes - 1 hour 10. Due to participants talking about their own work in the interviews, the data set is not openly available due to confidentiality considerations.
DOI: 10.6084/m9.figshare.3761562.v1348
title: Online Labour Index: Measuring the Online Gig Economy for Policy and Research

description: Data repository for the data underlying the Online Labour Index. See http://ilabour.oii.ox.ac.uk online-labour-index/ for details.
DOI: 10.6084/m9.figshare.3761562.v1349
title: Online Labour Index: Measuring the Online Gig Economy for Policy and Research

description: Data repository for the data underlying the Online Labour Index. See http://ilabour.oii.ox.ac.uk online-labour-index/ for details.
DOI: 10.25386/genetics.11516508
title: Supplemental Material for Di Stefano et al., 2020

description: Supplementary tables S3 and S4.<br><b>Supplementary Table 3. </b>Fold Change in Expression (mean, median and p value) of all genes.<b>Supplementary Table 4. </b>Fold Change in Expression (mean, median and p value) of genes that are displaced from more than 5% relative to the nuclear periphery, according to the models.<br>
DOI: 10.25386/genetics.11516508.v1
title: Supplemental Material for Di Stefano et al., 2020

description: Supplementary tables S3 and S4.<br><b>Supplementary Table 3. </b>Fold Change in Expression (mean, median and p value) of all genes.<b>Supplementary Table 4. </b>Fold Change in Expression (mean, median and p value) of genes that are displaced from more than 5% relative to the nuclear periphery, according to the models.<br>
DOI: 10.5281/zenodo.3939160
title: Signal, bias, and the role of transcriptome assembly quality in phylogenomic inference

description: Transcriptome assemblies of liver RNA-seq from 38 craniate taxa. Each taxon has two assemblies from the same read sets, one of high quality and one of low-quality according to overall TransRate score.
DOI: 10.5281/zenodo.3939159
title: Signal, bias, and the role of transcriptome assembly quality in phylogenomic inference

description: Transcriptome assemblies of liver RNA-seq from 38 craniate taxa. Each taxon has two assemblies from the same read sets, one of high quality and one of low-quality according to overall TransRate score.
DOI: 10.25405/data.ncl.11534097
title: Interviews and field notes from Ambit

description: Manuscripts of transcribed interview data, and memos and ethnographic field notes
DOI: 10.25386/genetics.11535675
title: Supplemental Material for Ding et al., 2020

description: Supplementary Material for Ding et al., 2020, including six Supplementary Figures.<br><b>Movie 1</b>: Sample 40-worm feeding experiments with DH5α-ilux bioluminescent bacteria. Top three samples are DA609 worms, middle three samples are N2 worms, bottom left and middle samples are DA1116 worms, bottom right sample is a no-worm control. The movie plays at 10800x real speed. <br><br><b>Movie 2</b>: A sample large population N2 swarming experiment with DH5α-ilux bioluminescent bacteria. The top right sample is a no-worm control. The movie plays at 1800x real speed. <br><br><b>Movie 3</b>: A sample large population N2 swarming experiment with OP50-GFP fluorescent bacteria. The top right sample is a no-worm control. The movie plays at 1800x real speed. <br><br><b>Movie 4</b>: A sample large population DA609 swarming experiment with DH5α-ilux bioluminescent bacteria. The top right sample is a no-worm control. The movie plays at 3600x real speed.<br><br><b>Movie 5</b>: Automatic detection of the migrating worm front in a sample large population N2 swarming experiment with DH5α-ilux bioluminescent bacteria. The bright field channel is shown on the left side and the bioluminescence channel is shown on the right side. The top right sample in each channel is a no-worm control. <br><br><b>Movie 6</b>: Automatic detection of the migrating worm front in a sample large population DA609 swarming experiment with DH5α-ilux bioluminescent bacteria. The bright field channel is shown on the left side and the bioluminescence channel is shown on the right side. The top right sample in each channel is a no-worm control.<br><br>
DOI: 10.25386/genetics.11535675.v1
title: Supplemental Material for Ding et al., 2020

description: Supplementary Material for Ding et al., 2020, including six Supplementary Figures.<br><b>Movie 1</b>: Sample 40-worm feeding experiments with DH5α-ilux bioluminescent bacteria. Top three samples are DA609 worms, middle three samples are N2 worms, bottom left and middle samples are DA1116 worms, bottom right sample is a no-worm control. The movie plays at 10800x real speed. <br><br><b>Movie 2</b>: A sample large population N2 swarming experiment with DH5α-ilux bioluminescent bacteria. The top right sample is a no-worm control. The movie plays at 1800x real speed. <br><br><b>Movie 3</b>: A sample large population N2 swarming experiment with OP50-GFP fluorescent bacteria. The top right sample is a no-worm control. The movie plays at 1800x real speed. <br><br><b>Movie 4</b>: A sample large population DA609 swarming experiment with DH5α-ilux bioluminescent bacteria. The top right sample is a no-worm control. The movie plays at 3600x real speed.<br><br><b>Movie 5</b>: Automatic detection of the migrating worm front in a sample large population N2 swarming experiment with DH5α-ilux bioluminescent bacteria. The bright field channel is shown on the left side and the bioluminescence channel is shown on the right side. The top right sample in each channel is a no-worm control. <br><br><b>Movie 6</b>: Automatic detection of the migrating worm front in a sample large population DA609 swarming experiment with DH5α-ilux bioluminescent bacteria. The bright field channel is shown on the left side and the bioluminescence channel is shown on the right side. The top right sample in each channel is a no-worm control.<br><br>
DOI: 10.6084/m9.figshare.11543418
title: Additional file 1 of Practising an explosive eruption in Iceland: outcomes from a European exercise

description: Additional file 1. Description of the Katla exercise.
DOI: 10.25405/data.ncl.11534985
title: OurPlace PBML Engagements

description: Workshop and classroom activities and anonymised highlights of data that informed the paper 'We are the Greatest Showmen: Configuring a Framework for Project-Based Mobile Learning'. The abstract for this research is below:<br><br>Following a design-based approach, we report on engagements spanning classroom and outdoor learning with students (ages 6-13) and teachers from three different UK schools and a summer school of Travelling Showchildren. Working within the time constraints of each context, we deployed a variety of configurations of a project-based mobile learning (PBML) framework intended to support the production of student-designed mobile learning activities. We contribute insights gained from these engagements, including how mobile technologies can harness students’ existing desire for independence and how they can be configured to leverage the physical and social attributes of place and community as learning resources. We argue for further exploration of the potential roles for mobile technologies within project-based learning, and contribute our PBML framework with recommendations for its re-configuration in response to contextual constraints. <br>
DOI: 10.25387/g3.11522544.v1
title: Supplemental Material for Susič et al., 2020

description: Supplemental data corresponding to the manuscript titled: Whole genome sequencing and comparative genomics of two nematicidal <i>Bacillus</i> strains reveals a wide range of possible virulence factors. The data include the morphological characteristics of the two studied strains; 16S analysis; detailed phylogenetic positioning of the two strains within the genus Bacillus; detailed ANI, Tetra and TCS scores; strain-specific homologous clusters and their GO-term affiliations; BLASTP hits for putative nematode-virulent proteases; putative chitinase sequences analysis; and predicted/putative secondary metabolite clusters (antiSMASH analysis).<br>
DOI: 10.25387/g3.11522544
title: Supplemental Material for Susič et al., 2020

description: Supplemental data corresponding to the manuscript titled: Whole genome sequencing and comparative genomics of two nematicidal <i>Bacillus</i> strains reveals a wide range of possible virulence factors. The data include the morphological characteristics of the two studied strains; 16S analysis; detailed phylogenetic positioning of the two strains within the genus Bacillus; detailed ANI, Tetra and TCS scores; strain-specific homologous clusters and their GO-term affiliations; BLASTP hits for putative nematode-virulent proteases; putative chitinase sequences analysis; and predicted/putative secondary metabolite clusters (antiSMASH analysis).<br>
DOI: 10.6084/m9.figshare.3761562.v1354
title: Online Labour Index: Measuring the Online Gig Economy for Policy and Research

description: Data repository for the data underlying the Online Labour Index. See http://ilabour.oii.ox.ac.uk online-labour-index/ for details.
DOI: 10.6084/m9.figshare.11565048
title: MOESM10 of Towards the restoration of the Mesoamerican Biological Corridor for large mammals in Panama: comparing multi-species occupancy to movement models

description: Additional file 10. Results - Estimates of the best supported SSF model for each individual.
DOI: 10.6084/m9.figshare.11565048.v1
title: MOESM10 of Towards the restoration of the Mesoamerican Biological Corridor for large mammals in Panama: comparing multi-species occupancy to movement models

description: Additional file 10. Results - Estimates of the best supported SSF model for each individual.
DOI: 10.25405/data.ncl.11494395.v1
title: Learning Ethics from Dementia Researchers in the Context of HCI

description: The data in this record is of qualitative discussions to gain an understanding of ethical experiences and practices in the field of HCI and dementia. These interviews took place between June and Early September 2019. The data set contains 22 anonymised interviews from diverse countries, institutions, and disciplines. These interviews range from 45 minutes - 1 hour 10. Due to participants talking about their own work in the interviews, the data set is not openly available due to confidentiality considerations.
DOI: 10.25405/data.ncl.11534985.v1
title: OurPlace PBML Engagements

description: Workshop and classroom activities and anonymised highlights of data that informed the paper 'We are the Greatest Showmen: Configuring a Framework for Project-Based Mobile Learning'. The abstract for this research is below:<br><br>Following a design-based approach, we report on engagements spanning classroom and outdoor learning with students (ages 6-13) and teachers from three different UK schools and a summer school of Travelling Showchildren. Working within the time constraints of each context, we deployed a variety of configurations of a project-based mobile learning (PBML) framework intended to support the production of student-designed mobile learning activities. We contribute insights gained from these engagements, including how mobile technologies can harness students’ existing desire for independence and how they can be configured to leverage the physical and social attributes of place and community as learning resources. We argue for further exploration of the potential roles for mobile technologies within project-based learning, and contribute our PBML framework with recommendations for its re-configuration in response to contextual constraints. <br>
DOI: 10.25573/serc.11569419
title: Dataset: Use of lead isotopes for developing chronologies in recent salt-marsh sediments

description: Dating of recent salt-marsh sediments is hindered by the radiocarbon plateau and the moving ∼100 year window of 210Pb accumulation histories. Introduction of anthropogenic Pb to the environment is a means to date salt-marsh sediment deposited over the last 200 years by correlating downcore changes in concentration and isotopic ratios to historical production and consumption. We investigated use of Pb as a chronometer in a core of salt-marsh sediment from New Jersey, USA. Changes in Pb concentration identified horizons at AD 1875, 1925, 1935 and 1974 that correspond to features of historic U.S Pb production and consumption. Stable lead isotopes (206Pb:207Pb) constrained ages at AD 1827, 1857 and 1880, reflecting Pb production in the Upper Mississippi Valley with its unusual isotopic signature and at AD 1965 and 1980 from leaded gasoline. Confirmatory evidence for the gasoline horizons came from increased Sb concentrations caused by vehicle emissions and industrial activity. These nine chronostratigraphic markers of fixed dates provide precise constraints on sediment age in the northeastern USA and enable salt-marsh records of coastal evolution and wetland development to extend beyond the period of instrumental measurements.
DOI: 10.6084/m9.figshare.3761562.v1355
title: Online Labour Index: Measuring the Online Gig Economy for Policy and Research

description: Data repository for the data underlying the Online Labour Index. See http://ilabour.oii.ox.ac.uk online-labour-index/ for details.
DOI: 10.6084/m9.figshare.3761562.v1358
title: Online Labour Index: Measuring the Online Gig Economy for Policy and Research

description: Data repository for the data underlying the Online Labour Index. See http://ilabour.oii.ox.ac.uk online-labour-index/ for details.
DOI: 10.25387/g3.11604990.v1
title: Supplemental Material for Cheng et al., 2020

description: Table S1 contains genes identified by transcriptome-wide association studies for attention deficiency/hyperactive disorder, autism spectrum disorder and cervical cancer (P value&lt;0.0001).
DOI: 10.25387/g3.11604990
title: Supplemental Material for Cheng et al., 2020

description: Table S1 contains genes identified by transcriptome-wide association studies for attention deficiency/hyperactive disorder, autism spectrum disorder and cervical cancer (P value&lt;0.0001).
DOI: 10.6084/m9.figshare.3761562.v1359
title: Online Labour Index: Measuring the Online Gig Economy for Policy and Research

description: Data repository for the data underlying the Online Labour Index. See http://ilabour.oii.ox.ac.uk online-labour-index/ for details.
DOI: 10.6084/m9.figshare.11626482
title: MOESM5 of Molecular epidemiology and antimicrobial resistance features of Acinetobacter baumannii clinical isolates from Pakistan

description: Additional file 5: Table S3. Genome assembly features of 25 clinical isolates of Acinetobacter baumannii collected in Pakistan between 2013 and 2015.
DOI: 10.6084/m9.figshare.11625603.v1
title: data2

description: Data for an MSR paper<br>
DOI: 10.6084/m9.figshare.11626467
title: MOESM2 of Molecular epidemiology and antimicrobial resistance features of Acinetobacter baumannii clinical isolates from Pakistan

description: Additional file 2: Table S1. Primers used for amplification and sequencing of the blaOXA-51-like and ampC loci in 52 clinical isolates of Acinetobacter baumannii collected in Pakistan between 2013 and 2015.
DOI: 10.6084/m9.figshare.11626473
title: MOESM3 of Molecular epidemiology and antimicrobial resistance features of Acinetobacter baumannii clinical isolates from Pakistan

description: Additional file 3: Table S2. Antimicrobial susceptibility results for 52 clinical isolates of Acinetobacter baumannii collected in Pakistan between 2013 and 2015.
DOI: 10.6084/m9.figshare.11626482.v1
title: MOESM5 of Molecular epidemiology and antimicrobial resistance features of Acinetobacter baumannii clinical isolates from Pakistan

description: Additional file 5: Table S3. Genome assembly features of 25 clinical isolates of Acinetobacter baumannii collected in Pakistan between 2013 and 2015.
DOI: 10.6084/m9.figshare.11626473.v1
title: MOESM3 of Molecular epidemiology and antimicrobial resistance features of Acinetobacter baumannii clinical isolates from Pakistan

description: Additional file 3: Table S2. Antimicrobial susceptibility results for 52 clinical isolates of Acinetobacter baumannii collected in Pakistan between 2013 and 2015.