cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q2445qrp
title: BindingDB Entry 50007036: Anti-biofilm Agents against

description: Small molecule binding data for protein Fucose-binding lectin PA-IIL, Uniprot Q9HYN5
DOI: 10.7270/q2445qs4
title: BindingDB Entry 50007305: Synthesis and SAR of 5-aryl-furan-2-carboxamide derivatives as potent urotensin-II receptor antagonists.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GSC2 and Urotensin-2 receptor, Uniprot P40989 and Q9UKP6
DOI: 10.7270/q2445qtk
title: BindingDB Entry 50007653: Investigation of Inactive-State κ Opioid Receptor Homodimerization via Single-Molecule Microscopy Using New Antagonistic Fluorescent Probes.

description: Small molecule binding data for protein Delta-type opioid receptor, Kappa-type opioid receptor, and Mu-type opioid receptor, Uniprot P35372, P41143, and P41145
DOI: 10.7270/q2445qv1
title: BindingDB Entry 50008259: Design, synthesis and evaluation of activity and pharmacokinetic profile of new derivatives of xanthone and piperazine in the central nervous system.

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 1A, 5-hydroxytryptamine receptor 2A, and 5-hydroxytryptamine receptor 2B, Uniprot P08908, P14842, P19327, P28223, and P41595
DOI: 10.7270/q2445qwg
title: BindingDB Entry 50008908: Defining Structure-Functional Selectivity Relationships (SFSR) for a Class of Non-Catechol Dopamine D

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 1A, 5-hydroxytryptamine receptor 1B, 5-hydroxytryptamine receptor 1D, 5-hydroxytryptamine receptor 1E, 5-hydroxytryptamine receptor 2A, 5-hydroxytryptamine receptor 2B, 5-hydroxytryptamine receptor 3A, 5-hydroxytryptamine receptor 4, 5-hydroxytryptamine receptor 5A, 5-hydroxytryptamine receptor 6, 5-hydroxytryptamine receptor 7, Alpha-1A adrenergic receptor, Alpha-1B adrenergic receptor, Alpha-2A adrenergic receptor, Beta-1 adrenergic receptor, Beta-2 adrenergic receptor, D(1A) dopamine receptor, D(1B) dopamine receptor, D(2) dopamine receptor, D(3) dopamine receptor, D(4) dopamine receptor, Histamine H1 receptor, Histamine H2 receptor, Kappa-type opioid receptor, Mu-type opioid receptor, Muscarinic acetylcholine receptor M1, Muscarinic acetylcholine receptor M2, Muscarinic acetylcholine receptor M3, Sigma non-opioid intracellular receptor 1, Sodium-dependent dopamine transporter, and Sodium-dependent serotonin transporter, Uniprot P07550, P08172, P08588, P08908, P08913, P11229, P14416, P20309, P21728, P21917, P21918, P25021, P28221, P28222, P28223, P28566, P31645, P34969, P35348, P35367, P35368, P35372, P35462, P41145, P41595, P46098, P47898, P50406, Q01959, Q13639, and Q99720
DOI: 10.7270/q2445qxx
title: BindingDB Entry 50009522: Medicinal properties of terpenes found in Cannabis sativa and Humulus lupulus.

description: Small molecule binding data for protein Cannabinoid receptor 2, Neuronal acetylcholine receptor subunit alpha-7, and Transient receptor potential cation channel subfamily A member 1, Uniprot O75762, P34972, and P36544
DOI: 10.7270/q2445qzc
title: BindingDB Entry 50009851: Discovery of a Potent and Selective Coactivator Associated Arginine Methyltransferase 1 (CARM1) Inhibitor by Virtual Screening.

description: Small molecule binding data for protein Histone-arginine methyltransferase CARM1, Protein arginine N-methyltransferase 1, Protein arginine N-methyltransferase 3, Protein arginine N-methyltransferase 5, Protein arginine N-methyltransferase 6, Protein arginine N-methyltransferase 7, and Protein arginine N-methyltransferase 8, Uniprot O14744, O60678, Q86X55, Q96LA8, Q99873, Q9NR22, and Q9NVM4
DOI: 10.7270/q2445r07
title: BindingDB Entry 50010127: Investigation around the Oxadiazole Core in the Discovery of a New Chemotype of Potent and Selective FXR Antagonists.

description: Small molecule binding data for protein Bile acid receptor, Uniprot Q96RI1
DOI: 10.7270/q2445r1p
title: BindingDB Entry 50010426: Histone deacetylase 8 (HDAC8) and its inhibitors with selectivity to other isoforms: An overview.

description: Small molecule binding data for protein 72 kDa type IV collagenase, Histone deacetylase 1/2/3/4/5/6/7/8/9/11/Polyamine deacetylase HDAC10, Histone deacetylase 2, Histone deacetylase 6, and Histone deacetylase 8, Uniprot O15379, P08253, P56524, Q13547, Q8WUI4, Q92769, Q969S8, Q96DB2, Q9BY41, Q9UBN7, Q9UKV0, and Q9UQL6
DOI: 10.7270/q2445r24
title: BindingDB Entry 50010702: Pro-apoptotic carboxamide analogues of natural fislatifolic acid targeting Mcl-1 and Bcl-2.

description: Small molecule binding data for protein Apoptosis regulator Bcl-2, Bcl-2-like protein 1, and Induced myeloid leukemia cell differentiation protein Mcl-1, Uniprot P10415, Q07817, and Q07820
DOI: 10.7270/q2445r3k
title: BindingDB Entry 50011048: Identification and Optimization of Pyrrolidine Derivatives as Highly Potent Ghrelin Receptor Full Agonists.

description: Small molecule binding data for protein Cytochrome P450 1A2, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A4, Growth hormone secretagogue receptor type 1, Kappa-type opioid receptor, and Mu-type opioid receptor, Uniprot P05177, P08684, P10635, P11712, P33261, P34975, P35372, P41145, and Q92847
DOI: 10.7270/q2445r41
title: BindingDB Entry 50011669: Discovery of PIPE-359, a Brain-Penetrant, Selective M

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GSC2, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A4, Muscarinic acetylcholine receptor M1, Muscarinic acetylcholine receptor M2, Muscarinic acetylcholine receptor M3, and Muscarinic acetylcholine receptor M4, Uniprot P08172, P08173, P08684, P10635, P11229, P11712, P20309, and P40989
DOI: 10.7270/q2445r5g
title: BindingDB Entry 50012292: Structure-activity relationship study of tryptophan-based butyrylcholinesterase inhibitors.

description: Small molecule binding data for protein Acetylcholinesterase and Cholinesterase, Uniprot P06276 and P22303
DOI: 10.7270/q2445r6x
title: BindingDB Entry 50012920: Chiral Analogues of PFI-1 as BET Inhibitors and Their Functional Role in Myeloid Malignancies.

description: Small molecule binding data for protein Bromodomain-containing protein 4, Uniprot O60885
DOI: 10.7270/q2445r7c
title: BindingDB Entry 50013279: Carvedilol serves as a novel CYP1B1 inhibitor, a systematic drug repurposing approach through structure-based virtual screening and experimental verification.

description: Small molecule binding data for protein Cytochrome P450 1B1, Uniprot Q16678
DOI: 10.7270/q2445r8t
title: BindingDB Entry 50013560: Discovery of Atabecestat (JNJ-54861911): A Thiazine-Based β-Amyloid Precursor Protein Cleaving Enzyme 1 Inhibitor Advanced to the Phase 2b/3 EARLY Clinical Trial.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GSC2, Beta-secretase 1, Beta-secretase 2, Cathepsin D, Cathepsin E, Cytochrome P450 1A2, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6, and Cytochrome P450 3A4, Uniprot P05177, P07339, P08684, P10635, P11712, P14091, P33261, P40989, P56817, P56818, and Q9Y5Z0
DOI: 10.7270/q2445r98
title: BindingDB Entry 50013916: Investigating the phosphinic acid tripeptide mimetic DG013A as a tool compound inhibitor of the M1-aminopeptidase ERAP1.

description: Small molecule binding data for protein Aminopeptidase N, Endoplasmic reticulum aminopeptidase 1, and Endoplasmic reticulum aminopeptidase 2, Uniprot P15144, Q6P179, and Q9NZ08
DOI: 10.7270/q2445rbq
title: BindingDB Entry 50014582: -Aromatic-Substituted Indazole Derivatives as Brain-Penetrant and Orally Bioavailable JNK3 Inhibitors.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GSC2, Casein kinase I isoform epsilon, Cytochrome P450 2C9, Cytochrome P450 3A4, Epithelial discoidin domain-containing receptor 1, Mitogen-activated protein kinase 10, Mitogen-activated protein kinase 14, Mitogen-activated protein kinase 8, and Mitogen-activated protein kinase 9, Uniprot P08684, P11712, P40989, P45983, P45984, P49674, P53779, Q08345, and Q16539
DOI: 10.7270/q2474dwd
title: BindingDB Entry 9401: ASK1 inhibitor and preparation method and use thereof

description: Small molecule binding data for protein Mitogen-activated protein kinase kinase kinase 5, Uniprot Q99683
DOI: 10.7270/q2474dxv
title: BindingDB Entry 9610: Compounds and their use as BACE1 inhibitors

description: Small molecule binding data for protein Beta-secretase 1, Beta-secretase 2, and Cathepsin D, Uniprot P07339, P56817, and Q9Y5Z0
DOI: 10.7270/q2474dz9
title: BindingDB Entry 9788: Small molecule inhibitors of lactate dehydrogenase and methods of use thereof

description: Small molecule binding data for protein L-lactate dehydrogenase A chain, Uniprot P00338
DOI: 10.7270/q2474f05
title: BindingDB Entry 9997: Compounds useful as inhibitors of indoleamine 2,3-dioxygenase and/or tryptophan dioxygenase

description: Small molecule binding data for protein Indoleamine 2,3-dioxygenase 1, Uniprot P14902
DOI: 10.7270/q2474f1m
title: BindingDB Entry 10175: Tri-substituted imidazoles for the inhibition of TGF beta and methods of treatment

description: Small molecule binding data for protein TGF-beta receptor type-1, Uniprot P36897
DOI: 10.7270/q2474f22
title: BindingDB Entry 10384: Prognostic biomarkers for TTK inhibitor chemotherapy

description: Small molecule binding data for protein Dual specificity protein kinase TTK, Uniprot P33981
DOI: 10.7270/q2474f3h
title: BindingDB Entry 10771: Hypoxia inducible factor-2(alpha) inhibitors and their use in the treatment of diseases

description: Small molecule binding data for protein Vascular endothelial growth factor A, Uniprot P15692
DOI: 10.7270/q2474f4z
title: BindingDB Entry 50006989: Discovery of 1,4-Naphthoquinones as a New Class of Antiproliferative Agents Targeting GPR55.

description: Small molecule binding data for protein G-protein coupled receptor 55, Uniprot Q9Y2T6
DOI: 10.7270/q2474f5d
title: BindingDB Entry 50007606: Recent advancements of 4-aminoquinazoline derivatives as kinase inhibitors and their applications in medicinal chemistry.

description: Small molecule binding data for protein Aurora kinase A, Aurora kinase B, Bromodomain-containing protein 4, Epidermal growth factor receptor, Inhibitor of nuclear factor kappa-B kinase subunit beta, Proto-oncogene tyrosine-protein kinase Src, Receptor tyrosine-protein kinase erbB-2, Receptor tyrosine-protein kinase erbB-3, Receptor tyrosine-protein kinase erbB-4, Serine/threonine-protein kinase PAK 1, Serine/threonine-protein kinase PAK 4, Tyrosine-protein kinase JAK1, Tyrosine-protein kinase JAK2, Tyrosine-protein kinase JAK3, Tyrosine-protein kinase Lck, Vascular endothelial growth factor receptor 2, and Vascular endothelial growth factor receptor 3, Uniprot O14920, O14965, O60674, O60885, O96013, P00533, P04626, P06239, P12931, P21860, P23458, P35916, P35968, P52333, Q13153, Q15303, and Q96GD4
DOI: 10.7270/q2474f6v
title: BindingDB Entry 50007927: Design, Synthesis, and Pharmacological Evaluation of Potent Positive Allosteric Modulators of the Glucagon-like Peptide-1 Receptor (GLP-1R).

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GSC2, Cytochrome P450 3A4, and Glucagon-like peptide 1 receptor, Uniprot O35659, P08684, P40989, and P43220
DOI: 10.7270/q2474f79
title: BindingDB Entry 50008209: A new series of bicalutamide, enzalutamide and enobosarm derivatives carrying pentafluorosulfanyl (SF

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GSC2 and Androgen receptor, Uniprot P15207 and P40989
DOI: 10.7270/q2474f8r
title: BindingDB Entry 50008530: Comparison of Orexin 1 and Orexin 2 Ligand Binding Modes Using X-ray Crystallography and Computational Analysis.

description: Small molecule binding data for protein Orexin receptor type 2 and Orexin/Hypocretin receptor type 1, Uniprot O43613 and O43614
DOI: 10.7270/q2474f96
title: BindingDB Entry 50009188: Medicinal chemistry of metal chelating fragments in metalloenzyme active sites: A perspective.

description: Small molecule binding data for protein Deoxyhypusine hydroxylase, Uniprot Q9BU89
DOI: 10.7270/q2474fbn
title: BindingDB Entry 50009812: Design, Synthesis, and Characterization of Cyclic Peptidomimetics of the Inducible Nitric Oxide Synthase Binding Epitope That Disrupt the Protein-Protein Interaction Involving SPRY Domain-Containing Suppressor of Cytokine Signaling Box Protein (SPSB) 2 and Inducible Nitric Oxide Synthase.

description: Small molecule binding data for protein SPRY domain-containing SOCS box protein 2, Uniprot O88838
DOI: 10.7270/q2474fc3
title: BindingDB Entry 50010382: Identification and Optimization of EphA2-Selective Bicycles for the Delivery of Cytotoxic Payloads.

description: Small molecule binding data for protein Ephrin type-A receptor 2, Uniprot P29317
DOI: 10.7270/q2474fdj
title: BindingDB Entry 50011001: Development of Conformationally Constrained α-RgIA Analogues as Stable Peptide Antagonists of Human α9α10 Nicotinic Acetylcholine Receptors.

description: Small molecule binding data for protein Neuronal acetylcholine receptor subunit alpha-10/alpha-9 and Neuronal acetylcholine receptor subunit alpha-7, Uniprot P36544, Q9GZZ6, and Q9UGM1
DOI: 10.7270/q2474ff0
title: BindingDB Entry 50011338: TBA

description: Small molecule binding data for protein 72 kDa type IV collagenase and Matrix metalloproteinase-9, Uniprot P08253 and P14780
DOI: 10.7270/q2474fgf
title: BindingDB Entry 50011621: Discovery of Pamiparib (BGB-290), a Potent and Selective Poly (ADP-ribose) Polymerase (PARP) Inhibitor in Clinical Development.

description: Small molecule binding data for protein Cytochrome P450 1A2, Cytochrome P450 2C19, Cytochrome P450 2C8, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A4, Poly [ADP-ribose] polymerase 1, Poly [ADP-ribose] polymerase 2, Poly [ADP-ribose] polymerase tankyrase-1, Poly [ADP-ribose] polymerase tankyrase-2, Protein mono-ADP-ribosyltransferase PARP10, Protein mono-ADP-ribosyltransferase PARP11, Protein mono-ADP-ribosyltransferase PARP12, Protein mono-ADP-ribosyltransferase PARP3, Protein mono-ADP-ribosyltransferase PARP6, Protein mono-ADP-ribosyltransferase PARP8, Protein mono-ADP-ribosyltransferase TIPARP, Solute carrier family 22 member 6, Solute carrier family 22 member 8, Solute carrier organic anion transporter family member 1B1, and Solute carrier organic anion transporter family member 1B3, Uniprot O95271, P05177, P08684, P09874, P10632, P10635, P11712, P33261, Q2NL67, Q4U2R8, Q53GL7, Q7Z3E1, Q8N3A8, Q8TCC7, Q9H0J9, Q9H2K2, Q9NPD5, Q9NR21, Q9UGN5, Q9Y6F1, and Q9Y6L6
DOI: 10.7270/q2474fhw
title: BindingDB Entry 50011977: Evaluation of 5-(Trifluoromethyl)-1,2,4-oxadiazole-Based Class IIa HDAC Inhibitors for Huntington's Disease.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GSC2, Cytochrome P450 1A2, Cytochrome P450 2C19, Cytochrome P450 2C8, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A4, Histone deacetylase 1/2/3/8, Histone deacetylase 2, Histone deacetylase 3/Nuclear receptor corepressor 2, Histone deacetylase 4, Histone deacetylase 5, Histone deacetylase 6, Histone deacetylase 7, Histone deacetylase 8, Histone deacetylase 9, Muscarinic acetylcholine receptor M1, Muscarinic acetylcholine receptor M2, Muscarinic acetylcholine receptor M3, and Muscarinic acetylcholine receptor M4, Uniprot O15379, P05177, P08172, P08173, P08684, P10632, P10635, P11229, P11712, P20309, P33261, P40989, P56524, Q13547, Q8WUI4, Q92769, Q9BY41, Q9UBN7, Q9UKV0, Q9UQL6, and Q9Y618
DOI: 10.7270/q2474fjb
title: BindingDB Entry 50012591: Pyrazolo[1,5a]pyrimidines as a new class of FUSE binding protein 1 (FUBP1) inhibitors.

description: Small molecule binding data for protein Far upstream element-binding protein 1, Uniprot Q96AE4
DOI: 10.7270/q2474fks
title: BindingDB Entry 50013222: Indole-like Trk receptor antagonists.

description: Small molecule binding data for protein BDNF/NT-3 growth factors receptor, High affinity nerve growth factor receptor, and NT-3 growth factor receptor, Uniprot P04629, Q16288, and Q16620
DOI: 10.7270/q2474fm7
title: BindingDB Entry 50013864: Discovery of a First-In-Class Small Molecule Antagonist against the Adrenomedullin-2 Receptor: Structure-Activity Relationships and Optimization.

description: Small molecule binding data for protein Calcitonin gene-related peptide 2 and Protein ADM2, Uniprot P10092 and Q7Z4H4
DOI: 10.7270/q2474fnp
title: BindingDB Entry 50014232: Gemfibrozil derivatives as activators of soluble guanylyl cyclase - A structure-activity study.

description: Small molecule binding data for protein Guanylate cyclase soluble subunit alpha-1/beta-1, Uniprot Q02108 and Q02153
DOI: 10.7270/q2474fp4
title: BindingDB Entry 50014520: Design, synthesis and evaluation of novel 9-arylalkyl-10-methylacridinium derivatives as highly potent FtsZ-targeting antibacterial agents.

description: Small molecule binding data for protein Cell division protein FtsZ, Uniprot A5Z1V5 and P0A9A6
DOI: 10.7270/q24b34c1
title: BindingDB Entry 9192: SARS-CoV-2 Mpro inhibitors with antiviral activity in a transgenic mouse model

description: Small molecule binding data for protein Replicase polyprotein 1ab, Uniprot P0DTD1
DOI: 10.7270/q24b34dg
title: BindingDB Entry 9579: Bicyclic amines as novel JAK kinase inhibitors

description: Small molecule binding data for protein Non-receptor tyrosine-protein kinase TYK2, Tyrosine-protein kinase JAK1, Tyrosine-protein kinase JAK2, and Tyrosine-protein kinase JAK3, Uniprot O60674, P23458, P29597, and P52333
DOI: 10.7270/q24b34fx
title: BindingDB Entry 9966: Pyrazolo[ 1,5a]pyrimidine derivatives as IRAK4 modulators

description: Small molecule binding data for protein Nuclear receptor ROR-gamma, Uniprot P51449
DOI: 10.7270/q24b34gc
title: BindingDB Entry 10353: Anti-proliferative agents for treating PAH

description: Small molecule binding data for protein Cyclin-dependent kinase 4/G1/S-specific cyclin-D1 and Cyclin-dependent kinase 6/G1/S-specific cyclin-D3, Uniprot P11802, P24385, P30281, and Q00534
DOI: 10.7270/q24b34ht
title: BindingDB Entry 10562: Substituted pyrrolo[1,2-a]pyrazines and pyrrolo[1,2-a][1,4]diazepines as TREX1 inhibitors

description: Small molecule binding data for protein Three-prime repair exonuclease 1, Uniprot Q91XB0 and Q9NSU2
DOI: 10.7270/q24b34j8
title: BindingDB Entry 10740: Treatment of upper aerodigestive tract disorders and cough

description: Small molecule binding data for protein Transient receptor potential cation channel subfamily M member 8, Uniprot Q7Z2W7
DOI: 10.7270/q24b34kq
title: BindingDB Entry 50005560: De Novo Design of Boron-Based Peptidomimetics as Potent Inhibitors of Human ClpP in the Presence of Human ClpX.

description: Small molecule binding data for protein ATP-dependent Clp protease proteolytic subunit, mitochondrial, Uniprot Q16740
DOI: 10.7270/q24b34m5
title: BindingDB Entry 50007260: Discovery of potent Pan-Raf inhibitors with increased solubility to overcome drug resistance.

description: Small molecule binding data for protein Discoidin domain-containing receptor 2, Ephrin type-A receptor 2, Epithelial discoidin domain-containing receptor 1, Fibroblast growth factor receptor 2, Macrophage colony-stimulating factor 1 receptor, Platelet-derived growth factor receptor beta, Proto-oncogene tyrosine-protein kinase receptor Ret, RAF proto-oncogene serine/threonine-protein kinase, Serine/threonine-protein kinase A-Raf, Serine/threonine-protein kinase B-raf, and Tyrosine-protein kinase Lck, Uniprot P04049, P06239, P07333, P07949, P09619, P10398, P15056, P21802, P29317, Q08345, and Q16832
DOI: 10.7270/q24b34nm
title: BindingDB Entry 50007867: Design, synthesis and biological evaluation of 2-hydrazinyladenosine derivatives as A

description: Small molecule binding data for protein Adenosine receptor A1 and Adenosine receptor A2a, Uniprot P29274 and P30542
DOI: 10.7270/q24b34p2
title: BindingDB Entry 50008477: Isolation, Structural Identification, Synthesis, and Pharmacological Profiling of 1,2-

description: Small molecule binding data for protein Amine oxidase [flavin-containing] B, Cytochrome P450 1A2, Cytochrome P450 3A4, Multidrug and toxin extrusion protein 1, and Utrophin, Uniprot P05177, P08684, P27338, P46939, and Q96FL8
DOI: 10.7270/q24b34qh
title: BindingDB Entry 50008859: New dual ligands for the D

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 1A, 5-hydroxytryptamine receptor 2A, 5-hydroxytryptamine receptor 6, 5-hydroxytryptamine receptor 7, and D(2) dopamine receptor, Uniprot P08908, P14416, P28223, P34969, and P50406
DOI: 10.7270/q24b34rz
title: BindingDB Entry 50009125: Rasagiline derivatives combined with histamine H

description: Small molecule binding data for protein Amine oxidase [flavin-containing] A, Amine oxidase [flavin-containing] B, D(2) dopamine receptor, D(3) dopamine receptor, Histamine H1 receptor, Histamine H3 receptor, and Histamine H4 receptor, Uniprot P14416, P19643, P21397, P27338, P35367, P35462, Q9H3N8, and Q9Y5N1
DOI: 10.7270/q24b34sd
title: BindingDB Entry 50009475: Design, synthesis and biological evaluation of benzoylacrylic acid shikonin ester derivatives as irreversible dual inhibitors of tubulin and EGFR.

description: Small molecule binding data for protein Epidermal growth factor receptor, Uniprot P00533
DOI: 10.7270/q24b34tv
title: BindingDB Entry 50010089: Novel small molecule binders of human N-glycanase 1, a key player in the endoplasmic reticulum associated degradation pathway.

description: Small molecule binding data for protein Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase, Uniprot Q96IV0
DOI: 10.7270/q24b34v9
title: BindingDB Entry 50010645: Discovery of Small-Molecule Stabilizers of 14-3-3 Protein-Protein Interactions via Dynamic Combinatorial Chemistry.

description: Small molecule binding data for protein 14-3-3 protein zeta/delta, Uniprot P63104
DOI: 10.7270/q24b34wr
title: BindingDB Entry 50011284: Novel tertiary sulfonamide derivatives containing benzimidazole moiety as potent anti-gastric cancer agents: Design, synthesis and SAR studies.

description: Small molecule binding data for protein Carbonic anhydrase 9, Uniprot Q16790
DOI: 10.7270/q24b34x6
title: BindingDB Entry 50011915: A study of the structure-affinity relationship in SYA16263; is a D

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 1A, 5-hydroxytryptamine receptor 2A, 5-hydroxytryptamine receptor 2C, 5-hydroxytryptamine receptor 7, D(2) dopamine receptor, D(3) dopamine receptor, D(4) dopamine receptor, and Sodium-dependent serotonin transporter, Uniprot P08908, P14416, P21917, P28223, P28335, P31645, P34969, and P35462
DOI: 10.7270/q24b34zn
title: BindingDB Entry 50012244: Synthesis of indole inhibitors of silent information regulator 1 (SIRT1), and their evaluation as cytotoxic agents.

description: Small molecule binding data for protein NAD-dependent protein deacetylase sirtuin-1 and NAD-dependent protein deacetylase sirtuin-2, Uniprot Q8IXJ6 and Q96EB6
DOI: 10.7270/q24b350h
title: BindingDB Entry 50012545: Design, synthesis, and biological evaluation of a novel series of peripheral-selective noradrenaline reuptake inhibitors-Part 2.

description: Small molecule binding data for protein Sodium-dependent dopamine transporter, Sodium-dependent noradrenaline transporter, and Sodium-dependent serotonin transporter, Uniprot P23975, P31645, and Q01959
DOI: 10.7270/q24b351z
title: BindingDB Entry 50012868: Novel Blocker of Onco SK3 Channels Derived from Scorpion Toxin Tamapin and Active against Migration of Cancer Cells.

description: Small molecule binding data for protein Small conductance calcium-activated potassium channel protein 2 and Small conductance calcium-activated potassium channel protein 3, Uniprot P70604 and Q9UGI6
DOI: 10.7270/q24b352d
title: BindingDB Entry 50013515: Gut-Restricted Selective Cyclooxygenase-2 (COX-2) Inhibitors for Chemoprevention of Colorectal Cancer.

description: Small molecule binding data for protein Prostaglandin G/H synthase 1 and Prostaglandin G/H synthase 2, Uniprot P23219, P35354, and Q05769