cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.3535/nh5-5k7-75k
title: Animalia

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/42m-pnx-3f9
title: Ctena decussata (O. G. Costa, 1829)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/xk2-2wz-by8
title: Conus loroisii Kiener, 1846

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/msl-5rc-0ye
title: Animalia

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/w26-9c5-cjz
title: Euglesa subtruncata (Malm, 1855)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/ax3-jtl-v3y
title: Monoplex pilearis (Linnaeus, 1758)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/al3-yvh-2se
title: Nodulus contortus (Jeffreys, 1856)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/k4j-2nq-7s0
title: Macrogastra plicatula plicatula (Draparnaud, 1801)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/c2z-199-yez
title: Gigahomalopoma carpenteri (Pilsbry, 1889)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/enm-ee7-gcz
title: Cochlicopa lubricella (Porro, 1838)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/fm4-xq2-pf1
title: Helix pathetica Mousson, 1854

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/j5f-r1v-hqx
title: Macrogastra attenuata lineolata (Held, 1836)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/1aa-4b1-1cn
title: Abida occidentalis (Fagot, 1888)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/j6z-bj2-zbd
title: Cecilioides acicula (O. F. Müller, 1774)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/qhm-3ln-l1z
title: Propeleda platessa (Dall, 1890)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/2ld-alv-pme
title: Monacha samsunensis (L. Pfeiffer, 1868)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/2s0-d1a-rx0
title: Helicina fasciata Lamarck, 1822

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.15468/dl.6epr33
title: Occurrence Download

description: A dataset containing 115280 species occurrences available in GBIF matching the query:
{
 "Geometry" : [
 "POLYGON((-74.03402 4.82433,-74.0306 4.80035,-74.02603 4.78094,-74.02318 4.76896,-74.01975 4.75583,-74.01347 4.74441,-74.01347 4.73585,-74.02032 4.73242,-74.02318 4.72386,-74.02546 4.70616,-74.02889 4.69132,-74.03402 4.6839,-74.03745 4.67477,-74.04487 4.66164,-74.05286 4.63994,-74.058 4.62111,-74.06199 4.61026,-74.05914 4.59428,-74.06428 4.58229,-74.0717 4.57372,-74.06485 4.56117,-74.07227 4.55831,-74.0814 4.56002,-74.0854 4.55032,-74.07684 4.54689,-74.0757 4.5389,-74.07912 4.52634,-74.08369 4.51036,-74.07969 4.49552,-74.08426 4.48467,-74.07798 4.46812,-74.07455 4.47668,-74.07113 4.51207,-74.05572 4.51093,-74.04201 4.51436,-74.03459 4.53605,-74.02774 4.56002,-74.00491 4.56174,-73.99578 4.61654,-74.00605 4.62339,-74.01518 4.63481,-74.03174 4.63652,-74.02432 4.66278,-74.01404 4.65992,-74.00434 4.66849,-74.00605 4.68047,-74.01404 4.69874,-74.00891 4.75526,-74.01576 4.75868,-74.01518 4.7935,-73.99749 4.80435,-74.00434 4.80892,-74.00377 4.81691,-74.01176 4.8209,-74.03402 4.82433))"
 ]
}

 The dataset includes 115280 records from 164 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0004067-250811113504898/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.3535/1g5-6f5-qzz
title: Animalia

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/4kh-jxa-y1k
title: Gonyodiscus rotundatus (O. F. Müller, 1774)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/91s-21b-c4q
title: Pomatias elegans (O. F. Müller, 1774)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/c0b-zxw-q47
title: Clathromangelia loiselieri Oberling, 1970

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/2h0-gwr-h2z
title: Tectura virginea (O. F. Müller, 1776)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/92h-sdn-9s7
title: Animalia

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/fve-lma-8ar
title: Helix philibinensis Rossmässler, 1839

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/s7j-kcr-qjb
title: Helicodonta obvoluta (O. F. Müller, 1774)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/2zy-6zx-sa1
title: Clausilia bidentata bidentata (Strøm, 1765)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/8ar-zt7-10c
title: Animalia

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/72x-vgn-sca
title: Merdigera obscura (O. F. Müller, 1774)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/he7-n5n-2ta
title: Valvata piscinalis (O. F. Müller, 1774)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/gas-ntn-td5
title: Callista erycina (Linnaeus, 1758)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/je2-jap-e11
title: Clio pyramidata Linnaeus, 1767

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/5cg-0cn-kes
title: Sciocochlea nordsiecki Subai, 1993

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/afm-01k-eae
title: Asaphis violascens (Forsskål, 1775)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/vwm-vmq-00c
title: Hastula hectica (Linnaeus, 1758)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/3wa-3dm-alj
title: Hyalocylis striata (Rang, 1828)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/ykf-dbl-vrg
title: Oxychilus draparnaudi (H. Beck, 1837)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/svr-q1e-1w1
title: Sepia officinalis Linnaeus, 1758

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/w95-7ar-qd7
title: Clausilia rugosa parvula (A. Férussac, 1807)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/xht-4rn-0ht
title: Oxychilus draparnaudi (H. Beck, 1837)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/kn0-et1-a13
title: Animalia

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/mq8-slt-kv6
title: Helicodonta obvoluta (O. F. Müller, 1774)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/jzh-t31-pcb
title: Bittium reticulatum (da Costa, 1778)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/keb-99g-a1k
title: Gonyodiscus perspectivus (Megerle von Mühlfeld, 1816)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/9z0-p9g-790
title: Aegopinella nitidula (Draparnaud, 1805)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/mqm-xm4-swg
title: Condylomitra tuberosa (Reeve, 1845)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/bkw-sex-mc9
title: Americardia biangulata (Broderip & G. B. Sowerby I, 1829)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/rsz-f6v-v9f
title: Orculella cretiminuta E. Gittenberger & Hausdorf, 2004

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/kdt-fzh-q25
title: Colubraria muricata ([Lightfoot, 1786])

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/ag5-pt8-4qt
title: Rossmaessleria sultana (Morelet, 1880)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/axk-vy5-ca1
title: Hydrorissoia gracilis Brandt, 1968

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/hly-526-hzy
title: Albinaria praeclara parallelifera (O. Boettger, 1878)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/4tx-qb0-9ay
title: Theba pisana (O. F. Müller, 1774)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/x7m-tb4-epp
title: Ciliella ciliata (W. Hartmann, 1821)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/bh0-3fx-l4m
title: Animalia

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/dpn-5sv-ees
title: Animalia

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/lt4-cy2-v96
title: Granaria frumentum illyrica (Rossmässler, 1835)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/4gx-cb3-js0
title: Mastus subaii Maassen, 1995

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/c18-lev-rb2
title: Orculella cretiminuta E. Gittenberger & Hausdorf, 2004

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/ds2-jmt-sl3
title: Retusa truncatula (Bruguière, 1792)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/gxx-090-gvx
title: Animalia

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/gfx-qhj-ar6
title: Venerupis aspera (Quoy & Gaimard, 1835)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/1z6-vq3-g8k
title: Taranis moerchii (Malm, 1861)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/tl2-766-3b9
title: Cochlicella acuta (O. F. Müller, 1774)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/laq-47w-gkm
title: Eatonina pumila (Monterosato, 1884)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/r65-mn7-w5r
title: Chondrina tenuimarginata (Des Moulins, 1835)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/9hc-4p4-dca
title: Cochlostoma scalarinum (A. Villa & G. B. Villa, 1841)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.15468/dl.j55bk3
title: Occurrence Download

description: A dataset listing the 26 species recorded in GBIF matching the query:
{
 "and" : [
 "Country is United States of America",
 "GadmGid is one of (USA.5.56_1, USA.5.19_1)",
 "TaxonKey is Baetidae"
 ]
}

 The dataset's 26 records were derived from 6 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0004070-250811113504898/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.3535/qcq-fy1-tzw
title: Acanthinula aculeata (O. F. Müller, 1774)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/sem-rzs-9n5
title: Macularia sylvatica (Draparnaud, 1801)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/byv-kr2-m44
title: Metafruticicola pellita (A. Férussac, 1832)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/qrf-vpl-5en
title: Helix figulina Rossmässler, 1839

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/gxl-ed0-fm5
title: Euplecta C. Semper, 1870

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/scv-xs9-j6v
title: Gradaterebra capensis (E. A. Smith, 1873)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/lpq-7h1-5xf
title: Pusillina philippi (Aradas & Maggiore, 1844)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/9wq-q7f-m1z
title: Hygromia limbata (Draparnaud, 1805)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/y0c-v9k-m54
title: Helicidae Rafinesque, 1815

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.15468/dl.ns8yh2
title: Occurrence Download

description: A dataset containing 396465 species occurrences available in GBIF matching the query:
{
 "and" : [
 {
 "or" : [
 "PublishingCountry is Colombia",
 {
 "and" : [
 "Country is Colombia",
 {
 "not" : {
 "Issue" : [
 "is Country coordinate mismatch"
 ]
 }
 }
 ]
 }
 ]
 },
 "GadmGid is one of (COL.12_2)"
 ]
}

 The dataset includes 396465 records from 325 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0004068-250811113504898/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.3535/173-f3j-bxt
title: Aegopinella nitidula (Draparnaud, 1805)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/kkv-t73-6q1
title: Viviparus Montfort, 1810

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/jcg-qbk-rtk
title: Lajonkairia lajonkairii (Payraudeau, 1826)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/6fy-yd6-pzd
title: Orculella ignorata Hausdorf, 1996

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/w7t-c9h-r3v
title: Aegopis gemonensis (A. Férussac, 1832)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/980-2c0-sp7
title: Xylophaga dorsalis (W. Turton, 1819)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/ptl-9xf-975
title: Leucozonia nassa (Gmelin, 1791)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/w9j-kzw-j9e
title: Vertigo pusilla O. F. Müller, 1774

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/9ye-gm1-ars
title: Metafruticicola noverca (L. Pfeiffer, 1853)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/x6j-x8w-22s
title: Alvania beanii (Hanley, 1844)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/b2f-m5p-6le
title: Alvania cancellata (da Costa, 1778)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/h4g-a5s-n07
title: Crisilla semistriata (Montagu, 1808)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/8pd-e9c-fc9
title: Eulimella acicula (R. A. Philippi, 1836)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/c20-njm-lbt
title: Rissoella diaphana (Alder, 1848)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.15468/dl.d4qb8t
title: Occurrence Download

description: A dataset containing 1134468 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Filipendula ulmaria"
 ]
}

 The dataset includes 1134468 records from 2295 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0004051-250811113504898/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5517/ccdc.csd.cc2n3fs0
title: CCDC 2446172: Experimental Crystal Structure Determination

description: Related Article: W. Clegg, L. Horsburgh, R.E. Mulvey, F.J. Craig|2025|CSD Communication|||
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2n3ft1
title: CCDC 2446173: Experimental Crystal Structure Determination

description: Related Article: W. Clegg, L. Horsburgh, R.E. Mulvey, F.J. Craig|2025|CSD Communication|||
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2n3fx4
title: CCDC 2446176: Experimental Crystal Structure Determination

description: Related Article: W. Clegg, L. Horsburgh, R.E. Mulvey, F.J. Craig|2025|CSD Communication|||
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2n3fy5
title: CCDC 2446177: Experimental Crystal Structure Determination

description: Related Article: W. Clegg, L. Horsburgh, R.E. Mulvey, F.J. Craig|2025|CSD Communication|||
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2n4t0n
title: CCDC 2447481: Experimental Crystal Structure Determination

description: Related Article: Frank R.  Fronczek|2025|CSD Communication|||
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2n66wz
title: CCDC 2448841: Experimental Crystal Structure Determination

description: Related Article: Rao M. Uppu, Frank R.  Fronczek|2025|CSD Communication|||
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.21233/dzzf-f817
title: Ecours pollen dataset

description: Raw data for the Ecours pollen dataset submitted to the Neotoma Paleoecology Database. Data is available through the landing page in JSON format. The landing page referenced by the DOI also contains links to publications and a map-based viewer for the dataset. The Neotoma Paleoecology Database maintains a homepage at https://www.neotomadb.org.
DOI: 10.6084/m9.figshare.29040216
title: Design, synthesis, characterization, and antimicrobial potential of peptide derivatives of jurubidine: <i>in-vitro</i> and <i>in-silico</i> study

description: Herein, we report the synthesis of peptide derivatives of Jurubidine (<b>2a–2h</b>) with a significant yield ranging from 79 to 88% which were characterised by <sup>1</sup>H NMR,<sup>13</sup>C NMR, Mass, and IR spectroscopy. Thereafter, we investigated their antimicrobial and antifungal potency through minimum inhibitory concentration (MIC), and virtually predict the possible mechanism of inhibition <i>via</i> targeting three key proteins. The antimicrobial activity for all the compounds ranging from 100 ± 2.20 to 220 ± 2.65 µg/mL against microbial strains was better than the reference drugs. The compounds <b>2g</b> and <b>2h</b> were having better MIC values against all the bacterial strains and also against fungal strains. Physiochemical properties and toxicity profile illustrated that <b>2h</b> followed by <b>2f</b> and <b>2g</b> were the best suitable drug candidate with high GI-absorption. In conclusion, <b>2g</b> (dipeptide derivative) was found to be most potent antifungal whereas <b>2h</b> (monopeptide derivative) was the most potent antibacterial compound.
DOI: 10.6084/m9.figshare.29040216.v1
title: Design, synthesis, characterization, and antimicrobial potential of peptide derivatives of jurubidine: <i>in-vitro</i> and <i>in-silico</i> study

description: Herein, we report the synthesis of peptide derivatives of Jurubidine (<b>2a–2h</b>) with a significant yield ranging from 79 to 88% which were characterised by <sup>1</sup>H NMR,<sup>13</sup>C NMR, Mass, and IR spectroscopy. Thereafter, we investigated their antimicrobial and antifungal potency through minimum inhibitory concentration (MIC), and virtually predict the possible mechanism of inhibition <i>via</i> targeting three key proteins. The antimicrobial activity for all the compounds ranging from 100 ± 2.20 to 220 ± 2.65 µg/mL against microbial strains was better than the reference drugs. The compounds <b>2g</b> and <b>2h</b> were having better MIC values against all the bacterial strains and also against fungal strains. Physiochemical properties and toxicity profile illustrated that <b>2h</b> followed by <b>2f</b> and <b>2g</b> were the best suitable drug candidate with high GI-absorption. In conclusion, <b>2g</b> (dipeptide derivative) was found to be most potent antifungal whereas <b>2h</b> (monopeptide derivative) was the most potent antibacterial compound.