cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.5652781
title: Audiències de televisió per l'últim any (octubre 2020 - octubre 2021)

description: <strong>El dataset obtingut ens proporciona una visió general de les audiències de cada cadena en cada una de les franges del dia. Aquestes franges són les estàndard utilitzades en el context de la televisió convencional. Per a cada dia i franja, tenim un percentatge d’audiència per cada una de les cadenes de TV (o agrupacions de cadenes, com ara les autonòmiques).</strong>
DOI: 10.5281/zenodo.5652780
title: Audiències de televisió per l'últim any (octubre 2020 - octubre 2021)

description: <strong>El dataset obtingut ens proporciona una visió general de les audiències de cada cadena en cada una de les franges del dia. Aquestes franges són les estàndard utilitzades en el context de la televisió convencional. Per a cada dia i franja, tenim un percentatge d’audiència per cada una de les cadenes de TV (o agrupacions de cadenes, com ara les autonòmiques).</strong>
DOI: 10.5281/zenodo.5652779
title: Raw data Morente and Ruano_N15 and C13 olive grove

description: The dataset contains data about de N15 and C13 isotopic content of different arthropos in the olive grove
DOI: 10.5281/zenodo.5652778
title: Raw data Morente and Ruano_N15 and C13 olive grove

description: The dataset contains data about de N15 and C13 isotopic content of different arthropos in the olive grove
DOI: 10.15151/esrf-es-541100571
title: Structural Biology BAG - Portugal

description: The Portuguese MX BAG includes 13 PIs from three different institutions. Our research interests include soluble and membrane proteins of biomedical interest from humans or pathogenic organisms, many of which can be drug targets. Focus is also given to structural enzymology, aimed at the elucidation of reaction mechanisms, active sites, and inhibition tolerance in proteins with potential biotechnology applications. In several cases, complementary structural biology approaches are being used, combining MX with SAXS and, more recently, CryoEM.
DOI: 10.15151/esrf-es-541058059
title: The Institute of Structural and Molecular Biology (ISMB) application for beam time, comprising groups from Birkbeck College, UCL and the Que

description: The ISMB spans Birkbeck and UCL with researchers in the core Departments at Birkbeck Biological Sciences and several UCL Research Departments. Research groups from Queen Mary University of London (QMUL) are joint co-applicants as they have strong links and collaborations with groups from ISMB. All groups share common interests in disciplines including structural, chemical, molecular and cell biology; using multidisciplinary and multiscalar approaches. ISMB, UCL and QMUL investigators, ranging from early-career research fellows to internationally-established senior academics, apply X-ray crystallography carried out mainly at our Wellcome funded facility at Birkbeck, as an essential method enabling: i) description of the atomic-level mechanistic details of macromolecules and macromolecular machines, and ii) structure-based drug discovery, while iii) complementing and supporting cryo-electron microscopy (cryo-EM) projects.
DOI: 10.15151/esrf-es-541411588
title: IBS BAG

description: The IBS BAG currently includes 24 IBS teams and 4 external groups from CERMAV and iRTSV/CEA (Grenoble), CEA-Cadarache (St Paul lez Durance) and IRBA (Brétigny-sur-Orge). We study structure-function relationships of proteins emphasizing in human health, biotechnology and methodology. Most of the projects can be grouped in different topics as follows: host-pathogen interaction, immunology, new drug targets, fundamental cellular mechanisms, membrane proteins, intrinsically disordered proteins, biotechnological applications and methodology. Some of these projects use integrative approaches (X-ray crystallography, SAXS, NMR (and cryo-EM), together with other biophysical studies) with the aim to fully understand the complexity of the biological macromolecular systems on study. Some other teams are dedicated to serial crystallography and its developments, for which the new ESRF-EBS might be the perfect tool.
DOI: 10.15151/esrf-es-551719805
title: Southampton, Bristol, Exeter, KCL, Portsmouth, UCL Royal Free Block Allocation Group (BAG)

description: This BAG coordinates activities of groups from the South-West of the UK. The focus is on projects in Immunology, transcriptional regulation, and enzymology. A particular strength are the macromolecular complexes that several of the groups target. The activities in rational protein design (Bristol) and enzyme design (Portsmouth) are particular highlight and have enriched the portfolio of projects of this ag since joining in 2020.
DOI: 10.15151/esrf-es-565653887
title: High-Resolution Powder X-ray Diffraction Study of Hybrid Single Crystals

description: Hybrid materials are an exciting new class of materials, where these promise novel functions and properties. However, their synthesis remains very challenging. This project will investigate a unique class of hybrid materials: single crystals containing foreign occlusions. We have developed a new strategy for generating hybrid crystals, where we have found that the addition of small amounts of organic solvents to the crystallisation medium facilitates the occlusion of high levels of additives in crystal hosts (calcium carbonate, calcium sulfate and manganese carbonate). With the ability to precisely tune the composition of the hybrid crystals, we now have a unique opportunity to investigate their structure/composition relationships. HR-PXRD will be used to determine how the crystal lattice is affected by the occlusions. This will provide vital insights into the occlusion mechanism in crystals and will ultimately enable the design of a novel functional materials with tunable properties.
DOI: 10.15151/esrf-es-551089324
title: Morphogenesis of crossed architectures in molluscan shells in 3D

description: Molluscan shells are a model system to study the most fundamental principles of biomineralization. Various shell structures are different in terms of their size, crystallography, shape and calcium carbonate polymorph of their mineral building blocks. Here, we propose to analyze pattern formation in the most common crossed shell architectures. Crossed-lamellar and cross-foliated structures, are unique architectures where the mineral building units are assembled to form crystallographically coherent domains. These domains evolve to form complex spatial configurations separated by twin-like abrupt changes in crystallographic texture. Astonishingly, in the case of molluscs, these domains can only be distinguished by the crystallographic orientation of the mineral units that comprise them. Following the evolution of the crossed patterns using 3D-XRD in ID13 will allow us to quantify the process of their formation in time and in space.
DOI: 10.15151/esrf-es-612768194
title: Gypsum 3dxrd

description: Gypsum crystallization
DOI: 10.15151/esrf-es-555094780
title: Nanoscale carbonate-oxalate mineralogy from the Great Barrier Reef: understanding pollution and climate change impacts during coral and sedi

description: As part of a broad study centred on the Low Isles reef near Port Douglas, we are studying the mineralogical, geochemical, and microbial populations in sediment and corals in order to better understand how organic minerals form in reef environments, their prominence, and the effects that climate change is having on the mineralogy and microorganisms present on the reef. By characterising the minerals present in the corals and sediment, we hope to for the first time develop an understanding of how susceptible certain corals are to acidification and rising sea temperatures.
DOI: 10.6084/m9.figshare.16943797
title: PEPC gene family data

description: PEPC gene family identified from 17 genomic datasets in “Convergent molecular evolution of phosphoenolpyruvate carboxylase gene family in C4 and crassulacean acid metabolism plants”
DOI: 10.6084/m9.figshare.16943797.v1
title: PEPC gene family data

description: PEPC gene family identified from 17 genomic datasets in “Convergent molecular evolution of phosphoenolpyruvate carboxylase gene family in C4 and crassulacean acid metabolism plants”
DOI: 10.5281/zenodo.4889182
title: Data for "Diversity of Non-Equilibrium Patterns and Emergence of Activity in Confined Electrohydrodynamically Driven Liquids"

description: Raw data (microscopy videos and image sequences) and scripts used for the analysis for the publication "Diversity of Non-Equilibrium Patterns and Emergence of Activity in Confined Electrohydrodynamically Driven Liquids", Science Advances 7 (38), eabh1642
DOI: 10.5281/zenodo.4889181
title: Data for "Diversity of Non-Equilibrium Patterns and Emergence of Activity in Confined Electrohydrodynamically Driven Liquids"

description: Raw data (microscopy videos and image sequences) and scripts used for the analysis for the publication "Diversity of Non-Equilibrium Patterns and Emergence of Activity in Confined Electrohydrodynamically Driven Liquids", Science Advances 7 (38), eabh1642
DOI: 10.6084/m9.figshare.16948570.v1
title: Isotope disequilibrium caused by the influx of fluids during crustal anatexis

description: Isotope disequilibrium during crustal anatexis is increasingly recognized in the magmatic systems, which is usually attributed to stoichiometry or peritectic phases of melting reactions. However, whether fluid influx can contribute to isotope disequilibrium during fluid-fluxed melting remains poorly constrained. Here we report combined Mg-O-Sr isotopic data for migmatites from Dabie orogen. Except for one sample that has experienced post-migmatization metasomatism, leucosomes show considerably lower δ<sup>26</sup>Mg (-0.71‰ ~ -0.23‰) and δ<sup>18</sup>O (3.7‰ ~ 8.7‰) but higher <sup>87</sup>Sr/<sup>86</sup>Sr(i) (0.7089 ~ 0.7131) than the corresponding melanosomes (-0.29‰ ~ -0.11‰, 6.9‰ ~ 10.6‰ and 0.7080 ~ 0.7119, respectively). Such isotopic difference between leucosomes and melanosomes cannot result from fractionation during either fractional crystallization, accumulation or equilibrium, incongruent to non-modal melting, but most likely records isotope disequilibrium during crustal anatexis. Co-variations of δ<sup>18</sup>O, δ<sup>26</sup>Mg and <sup>87</sup>Sr/<sup>86</sup>Sr(i) of leucosomes indicate influx of external fluids and their preferential partition into melts. The external fluids could have low δ<sup>18</sup>O and δ<sup>26</sup>Mg but high <sup>87</sup>Sr/<sup>86</sup>Sr(i) and were most likely derived from dehydration of the surrounding eclogites and gneisses with Neoproterozoic protoliths experienced meteoric-hydrothermal exchange. One leucosome is plotted off the major trends by its rather low δ<sup>26</sup>Mg (~ -0.71‰), and may have been overprinted by Fe-Mg inter-diffusion. Simple diffusion calculations suggested that the timescale to reach isotopic equilibration during fluid-fluxed melting is larger by one order of magnitude than that of dehydration melting. Hence, fluid-fluxed melting may generate melts out of isotope equilibrium with restite, and cautions should be taken in interpretation of isotopic data of the resulting granitoids.
DOI: 10.6084/m9.figshare.16948570
title: Isotope disequilibrium caused by the influx of fluids during crustal anatexis

description: Isotope disequilibrium during crustal anatexis is increasingly recognized in the magmatic systems, which is usually attributed to stoichiometry or peritectic phases of melting reactions. However, whether fluid influx can contribute to isotope disequilibrium during fluid-fluxed melting remains poorly constrained. Here we report combined Mg-O-Sr isotopic data for migmatites from Dabie orogen. Except for one sample that has experienced post-migmatization metasomatism, leucosomes show considerably lower δ<sup>26</sup>Mg (-0.71‰ ~ -0.23‰) and δ<sup>18</sup>O (3.7‰ ~ 8.7‰) but higher <sup>87</sup>Sr/<sup>86</sup>Sr(i) (0.7089 ~ 0.7131) than the corresponding melanosomes (-0.29‰ ~ -0.11‰, 6.9‰ ~ 10.6‰ and 0.7080 ~ 0.7119, respectively). Such isotopic difference between leucosomes and melanosomes cannot result from fractionation during either fractional crystallization, accumulation or equilibrium, incongruent to non-modal melting, but most likely records isotope disequilibrium during crustal anatexis. Co-variations of δ<sup>18</sup>O, δ<sup>26</sup>Mg and <sup>87</sup>Sr/<sup>86</sup>Sr(i) of leucosomes indicate influx of external fluids and their preferential partition into melts. The external fluids could have low δ<sup>18</sup>O and δ<sup>26</sup>Mg but high <sup>87</sup>Sr/<sup>86</sup>Sr(i) and were most likely derived from dehydration of the surrounding eclogites and gneisses with Neoproterozoic protoliths experienced meteoric-hydrothermal exchange. One leucosome is plotted off the major trends by its rather low δ<sup>26</sup>Mg (~ -0.71‰), and may have been overprinted by Fe-Mg inter-diffusion. Simple diffusion calculations suggested that the timescale to reach isotopic equilibration during fluid-fluxed melting is larger by one order of magnitude than that of dehydration melting. Hence, fluid-fluxed melting may generate melts out of isotope equilibrium with restite, and cautions should be taken in interpretation of isotopic data of the resulting granitoids.
DOI: 10.34740/kaggle/dsv/2787658
title: AutoXGB
DOI: 10.6084/m9.figshare.16948864
title: Supplementary Material for: Unusually High Prevalence of Stroke and Cerebral Vasculopathy in Hemoglobin SC Disease: A Retrospective Single Institution Study

description: <b><i>Introduction:</i></b> Unlike homozygous hemoglobin SS (HbSS) disease, stroke is a rare complication in hemoglobin SC (HbSC) disease. However, recent studies have demonstrated a high prevalence of silent stroke in HbSC disease. The factors associated with stroke and cerebral vasculopathy in the HbSC population are unknown. <b><i>Methods:</i></b> We conducted a retrospective study of all patients with sickle cell disease treated at the University of Missouri, Columbia, over an 18-year period (2000–2018). The goal of the study was to characterize the silent, overt stroke, and cerebral vasculopathy in HbSC patients and compare them to patients with HbSS and HbS/β thalassemia1 (thal) in this cohort. We also analyzed the laboratory and clinical factors associated with stroke and cerebral vasculopathy in the HbSC population. <b><i>Results:</i></b> Of the 34 HbSC individuals, we found that the overall prevalence of stroke and cerebral vasculopathy was 17.7%. Only females had evidence of stroke or cerebral vasculopathy in our HbSC cohort (33.3%, <i>p</i> = 0.019). Time-averaged means of maximum velocities were lower in the HbSC group than the HbSS group and did not correlate with stroke outcome. Among HbSC individuals, those with stroke and cerebral vasculopathy had a marginally higher serum creatinine than those without these complications (0.77 mg/dL vs. 0.88 mg/dL, <i>p</i> = 0.08). Stroke outcome was associated with recurrent vaso-occlusive pain crises (Rec VOCs) (75 vs. 25%, <i>p</i> = 0.003) in HbSC patients. The predominant cerebrovascular lesions in HbSC included microhemorrhages and leukoencephalopathy. <b><i>Conclusion:</i></b> There is a distinct subset of individuals with HbSC who developed overt, silent stroke, and cerebral vasculopathy. A female predominance and association with Rec VOCs were identified in our cohort; however, larger clinical trials are needed to identify and confirm specific clinical and laboratory markers associated with stroke and vasculopathy in HbSC disease.
DOI: 10.6084/m9.figshare.16948864.v1
title: Supplementary Material for: Unusually High Prevalence of Stroke and Cerebral Vasculopathy in Hemoglobin SC Disease: A Retrospective Single Institution Study

description: <b><i>Introduction:</i></b> Unlike homozygous hemoglobin SS (HbSS) disease, stroke is a rare complication in hemoglobin SC (HbSC) disease. However, recent studies have demonstrated a high prevalence of silent stroke in HbSC disease. The factors associated with stroke and cerebral vasculopathy in the HbSC population are unknown. <b><i>Methods:</i></b> We conducted a retrospective study of all patients with sickle cell disease treated at the University of Missouri, Columbia, over an 18-year period (2000–2018). The goal of the study was to characterize the silent, overt stroke, and cerebral vasculopathy in HbSC patients and compare them to patients with HbSS and HbS/β thalassemia1 (thal) in this cohort. We also analyzed the laboratory and clinical factors associated with stroke and cerebral vasculopathy in the HbSC population. <b><i>Results:</i></b> Of the 34 HbSC individuals, we found that the overall prevalence of stroke and cerebral vasculopathy was 17.7%. Only females had evidence of stroke or cerebral vasculopathy in our HbSC cohort (33.3%, <i>p</i> = 0.019). Time-averaged means of maximum velocities were lower in the HbSC group than the HbSS group and did not correlate with stroke outcome. Among HbSC individuals, those with stroke and cerebral vasculopathy had a marginally higher serum creatinine than those without these complications (0.77 mg/dL vs. 0.88 mg/dL, <i>p</i> = 0.08). Stroke outcome was associated with recurrent vaso-occlusive pain crises (Rec VOCs) (75 vs. 25%, <i>p</i> = 0.003) in HbSC patients. The predominant cerebrovascular lesions in HbSC included microhemorrhages and leukoencephalopathy. <b><i>Conclusion:</i></b> There is a distinct subset of individuals with HbSC who developed overt, silent stroke, and cerebral vasculopathy. A female predominance and association with Rec VOCs were identified in our cohort; however, larger clinical trials are needed to identify and confirm specific clinical and laboratory markers associated with stroke and vasculopathy in HbSC disease.
DOI: 10.6084/m9.figshare.16949275
title: Supplementary Material for: Predicting Severe Renal and Gastrointestinal Involvement in Childhood Immunoglobulin A Vasculitis with Routine Laboratory Parameters

description: <b><i>Background:</i></b> Immunoglobulin A vasculitis (IgAV) is the most common vasculitis in children. Although childhood IgAV is generally considered as a self-limited disease, progressive course and poor prognosis could occur in some cases which mostly result from severe renal involvement and gastrointestinal (GI) involvement. <b><i>Methods:</i></b> We performed a retrospective study of pediatric patients diagnosed as IgAV in our institution from 2016 to 2019. Patients were divided into groups based on the occurrence and severity of GI and renal involvement. Analysis of variance (ANOVA) and Kruskal-Wallis test were used to compare results of laboratory parameters among groups and prediction models were built by using logistic regression analysis. <b><i>Results:</i></b> A total of 286 patients were enrolled. GI involvement occurred in 148 (51.7%) patients, 30 (20.3%) of which were severe cases. Renal involvement developed in 120 (42.0%) patients, 22 (18.3%) of which were severe cases. Compared with patients with only cutaneous manifestations, white blood cell (WBC) count, neutrophil-to-lymphocyte ratio (NLR), and D-dimer levels were higher in those with GI involvement, and D-dimer level was found to be positively associated with severity. Increased NLR and lower complement 3 (C3) were found in patients with renal involvement, but only C3 was relevant in distinguishing moderate and severe cases. The prediction model for severe renal involvement was: Logit (P) = 6.820 + 0.270 (age) + 0.508 (NLR) − 16.130 (C3), with an AUC of 0.914. The prediction model for severe GI involvement was: Logit (P) = −5.459 + 0.005 (WBC) + 1.355 (D-dimer) – 0.020 (NLR), with an AUC of 0.849. <b><i>Conclusion:</i></b> Our data suggest C3 to be an exclusive predictor for severe renal involvement and D-dimer level to be positively associated with the severity of GI involvement. Prediction models consisting of the above parameters were built for obtaining prognostic information in the early phase of IgAV.
DOI: 10.6084/m9.figshare.16949275.v1
title: Supplementary Material for: Predicting Severe Renal and Gastrointestinal Involvement in Childhood Immunoglobulin A Vasculitis with Routine Laboratory Parameters

description: <b><i>Background:</i></b> Immunoglobulin A vasculitis (IgAV) is the most common vasculitis in children. Although childhood IgAV is generally considered as a self-limited disease, progressive course and poor prognosis could occur in some cases which mostly result from severe renal involvement and gastrointestinal (GI) involvement. <b><i>Methods:</i></b> We performed a retrospective study of pediatric patients diagnosed as IgAV in our institution from 2016 to 2019. Patients were divided into groups based on the occurrence and severity of GI and renal involvement. Analysis of variance (ANOVA) and Kruskal-Wallis test were used to compare results of laboratory parameters among groups and prediction models were built by using logistic regression analysis. <b><i>Results:</i></b> A total of 286 patients were enrolled. GI involvement occurred in 148 (51.7%) patients, 30 (20.3%) of which were severe cases. Renal involvement developed in 120 (42.0%) patients, 22 (18.3%) of which were severe cases. Compared with patients with only cutaneous manifestations, white blood cell (WBC) count, neutrophil-to-lymphocyte ratio (NLR), and D-dimer levels were higher in those with GI involvement, and D-dimer level was found to be positively associated with severity. Increased NLR and lower complement 3 (C3) were found in patients with renal involvement, but only C3 was relevant in distinguishing moderate and severe cases. The prediction model for severe renal involvement was: Logit (P) = 6.820 + 0.270 (age) + 0.508 (NLR) − 16.130 (C3), with an AUC of 0.914. The prediction model for severe GI involvement was: Logit (P) = −5.459 + 0.005 (WBC) + 1.355 (D-dimer) – 0.020 (NLR), with an AUC of 0.849. <b><i>Conclusion:</i></b> Our data suggest C3 to be an exclusive predictor for severe renal involvement and D-dimer level to be positively associated with the severity of GI involvement. Prediction models consisting of the above parameters were built for obtaining prognostic information in the early phase of IgAV.
DOI: 10.25405/data.ncl.16918357.v1
title: Let’s talk transition in haemophilia interview transcripts

description: This presents qualitative interview transcripts from interviews of caregivers of young people with haemophilia. The interview process aimed to highlight barriers and facilitators within the process of transition, enhanced by the integration of existing psychological theory. <br>
DOI: 10.25405/data.ncl.16918357
title: Let’s talk transition in haemophilia interview transcripts

description: This presents qualitative interview transcripts from interviews of caregivers of young people with haemophilia. The interview process aimed to highlight barriers and facilitators within the process of transition, enhanced by the integration of existing psychological theory. <br>
DOI: 10.6084/m9.figshare.16691323
title: Fish_growth_data_set

description: Daily increment of fish otoliths of chub young of the year, they length at capture and the environmental conditions in which they grew up (sector, year, temperature, discharge).
DOI: 10.5445/ir/1000139453
title: MIPAS monthly zonal mean Age of Air data, based on MIPAS SF6 retrievals, processed at KIT-IMK, Karlsruhe

description: Aus den Infrarotspektren der Jahre 2002-2012 des Satelliteninstrumentes MIPAS wurde die räumliche und zeitliche Verteilung von SF6 berechnet. Daraus wurden zonale Monatsmittelwerte des Luftalters (Age of Air) in 30 jeweils 6 Grad umfassenden Breitenbereichen bestimmt. Die Berechnung des Luftalters ist beschrieben in Haenel et al. (2015) [https://doi.org/10.5194/acp-15-13161-2015], die SF6-Daten für den vorliegenden Datensatz (Versionen V5H_SF6_21 und V5R_SF6_224/225) wurden jedoch berechnet mit den neueren Spektroskopiedaten für SF6 und CFC-11 von J.J.Harrison (2018,2020) [https://doi.org/10.5194/amt-11-5827-2018, https://doi.org/10.1016/j.jqsrt.2020.107202].