cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7899179.v1
title: Booklet content validation on excess weight for adults with hypertension

description: ABSTRACT Objective: To validate the content and appearance of an educational booklet about excess weight for adults with hypertension. Method: Methodological study in which an educational booklet was developed from theoretical material on hypertension, chronic diseases and obesity, as well as guiding points for the clinical practice of the nurse in the care of young adults with excess weight and based on the Transtheoretical Model. Twenty-one specialists participated in the validation of content and appearance, being 9 teachers, 7 technicians and 5 designers. Results: The Global Content Validity Index was 0.78 and the material was considered appropriate or superior. The experts suggested adjustments, incorporated into the material for print production of the final version. Conclusion: The educational booklet for people with hypertension and excess weight was considered valid regarding content and appearance.
DOI: 10.6084/m9.figshare.7899161
title: Theoretical Study of Plasmonically Induced Transparency Effect in Arrays of Graphene-Based Double Disk Resonators

description: Abstract In this paper, we consider coupled disk-shaped resonators separated by a thin dielectric substrate that can be used as frequency-tunable filters or as electromagnetic switches in the terahertz frequency band. The two disks are electromagnetically coupled and resonate with dipole plasmonic modes. By using a Temporal Coupled-Mode Theory based approach, we show how to analytically calculate the frequency response of such structures.The analytical results are in good agreement with those obtained from computational simulations based on the finite element method.
DOI: 10.6084/m9.figshare.7899167.v1
title: Innominate vs. Axillary Artery Cannulation in Aortic Surgery: a Systematic Review and Meta-Analysis

description: Abstract Objective: To investigate whether axillary artery cannulation has supremacy over innominate artery cannulation in thoracic aortic surgery. Methods: A comprehensive search was undertaken among the four major databases (PubMed, Excerpta Medica dataBASE [EMBASE], Scopus, and Ovid) to identify all randomized and nonrandomized controlled trials comparing axillary to innominate artery cannulation in thoracic aortic surgery. Databases were evaluated and assessed up to March 2017. Results: Only three studies fulfilled the criteria for this meta-analysis, including 534 patients. Cardiopulmonary bypass time was significantly shorter in the innominate group (P=0.004). However, the innominate group had significantly higher risk of prolonged intubation &gt; 48 hours (P=0.04) than the axillary group. Further analysis revealed no significant difference between the innominate and axillary groups for deep hypothermic circulatory arrest time (P=0.06). The relative risks for temporary and permanent neurological deficits as well as in-hospital mortality were not significantly different for both groups (P=0.90, P=0.49, and P=0.55, respectively). Length of hospital stay was similar for both groups. Conclusion: There is no superiority of axillary over innominate artery cannulation in thoracic aortic surgery in terms of perioperative outcomes; however, as the studies were limited, larger scale comparative studies are required to provide a solid evidence base for choosing optimal arterial cannulation site.
DOI: 10.6084/m9.figshare.7899170.v1
title: Filaggrin silencing by shRNA directly impairs the skin barrier function of normal human epidermal keratinocytes and then induces an immune response

description: The objective of this study was to investigate whether a single defect in skin barrier function simulated by filaggrin silencing could induce Th2-predominant inflammation. Filaggrin gene expression was silenced in cultured normal human epidermal keratinocytes (NHEKs) using small hairpin RNA (shRNA, GTTGGCTCAAGCATATTATTT). The efficacy of silencing was confirmed by polymerase chain reaction (PCR) and Western blotting. Filaggrin-silenced cells (LV group), shRNA control cells (NC group), and noninfected cells (Blank group) were evaluated. The expression of cornified cell envelope-related proteins, including cytokeratin (CK)-5, -10, -14, loricrin, involucrin, and transglutaminase (TGM)-1, was detected by Western blotting. Interleukins (IL)-2, IL-4, IL-5, IL-12p70, IL-13, and interferon-gamma (IFN-γ) were detected by enzyme-linked immunosorbent assay (ELISA). After filaggrin was successfully silenced by shRNA, the expressions of CK-5, -10, -14, involucrin, and TGM-1 in NHEKs were significantly downregulated compared to the Blank and NC groups (P&lt;0.05 or P&lt;0.01); only loricrin expression was markedly upregulated (P&lt;0.01). Filaggrin silencing also resulted in significant increases of IL-2, IL-4, IL-5, and IL-13 (P&lt;0.05 or P&lt;0.01), and significant decreases of IL-12p70 and IFN-γ (P&lt;0.01) compared with cells in the Blank and NC groups. Filaggrin silencing impaired normal skin barrier function mainly by targeting the cornified cell envelope. The immune response after filaggrin silencing was characterized by Th2 cells, mainly because of the inhibition of IFN-γ expression. Lack of filaggrin may directly impair skin barrier function and then further induce the immune response.
DOI: 10.6084/m9.figshare.7899173.v1
title: Dexamethasone and sodium carboxymethyl cellulose prevent postoperative intraperitoneal adhesions in rats

description: We aimed to evaluate the effects of the barrier agent sodium carboxymethyl cellulose (SCMC) with and without dexamethasone for the prevention of postoperative adhesion formation in a rat model of postoperative peritoneal adhesion. A total of 160 three-month old male and female Wistar rats underwent a laparotomy, and adhesions were induced by ileocecal abrasion. Rats were randomly assigned to 4 groups (n=40 each): group A, untreated; group B, treated with SCMC only; group C1, treated with SCMC + 3 mg dexamethasone, and group C2, treated with SCMC + 8 mg dexamethasone. After 12 days, adhesion formation and histopathological changes were compared. In groups A, B, C1, and C2, the mortality rates were 10, 5, 5, and 5%, respectively. In groups C1 and C2, the adhesions were filmy and easy to dissect and were milder compared with those in groups A and B. The total adhesion score in group C1 (3.38±0.49) was significantly lower than that of group B (6.01±0.57; P&lt;0.01) or group A (8.01±0.67; P&lt;0.05). There was no significant difference in adhesion formation between groups C1 and C2. Compared with groups A and B, groups C1 and C2 exhibited milder histopathological changes. SCMC in combination with dexamethasone can prevent adhesion formation and is a better barrier agent than SCMC alone. The safety and feasibility of SCMC in combination with dexamethasone to prevent adhesion formation after abdominal surgery warrants further clinical study.
DOI: 10.6084/m9.figshare.7899152
title: Elderly care: performance of interventions carried out by More Doctors Program professionals

description: ABSTRACT In order to assess coverage and quality of elderly care, a cross-sectional study of 204 interventions of Family Health Specialization students of UFPel was conducted, both connected and not connected to the More Doctors Program (PMM). The coverage difference between the third and first months of intervention and the percentage at the end of the third month were calculated in order to obtain quality indicators. An average increase in coverage of 35.7 percentage points (pp) (32.9, 38.6) was found: 42.1 pp (38.6, 45.7) and 26.1 pp (22.3, 30) were, respectively, related and not related to PMM. Brief Multidimensional Assessment (AMR), up-to-date clinical examination and assessment of the need for dental treatment showed better results in interventions conducted by PMM professionals. The interventions were effective regardless of supply and nationality, obtaining significantly better results those conducted by PMM professionals, especially Cubans.
DOI: 10.6084/m9.figshare.7899155
title: A methodology to determine size and shape of plots for sugarcane plantation

description: ABSTRACT: Brazil is the largest sugarcane producer in the world and the leader in the production of sugar and ethanol. Although sugarcane has become an important factor in the Brazilian economy, cultivation has presented many issues, for example, the problems due to burning before the manual harvest. The Brazilian authorities have approved a law that prohibits this practice and mechanized harvesting has thus become the most fitting approach. Given this development, areas for sugarcane plantation must be properly rebuilt to accommodate the new way of harvesting. The main characteristic demanded of sugarcane plots to use harvesting machines is that they must be rectangular. In the present paper, we propose a methodology for dividing the plantation area into plots and planning their allocation so as to accommodate mechanized harvesting. In view of the requirement for plots to be rectangular, we represented this problem as a two-dimensional cutting problem, and to find a solution we adopted the AND/OR graph approach. The computational experiments were conducted using real cases, and the proposed strategy was shown to perform well.
DOI: 10.6084/m9.figshare.7899149
title: Caryocar brasiliense camb protects against genomic and oxidative damage in urethane-induced lung carcinogenesis

description: The antioxidant effects of Caryocar brasiliense Camb, commonly known as the pequi fruit, have not been evaluated to determine their protective effects against oxidative damage in lung carcinogenesis. In the present study, we evaluated the role of pequi fruit against urethane-induced DNA damage and oxidative stress in forty 8-12 week old male BALB/C mice. An in vivo comet assay was performed to assess DNA damage in lung tissues and changes in lipid peroxidation and redox cycle antioxidants were monitored for oxidative stress. Prior supplementation with pequi oil or its extract (15 µL, 60 days) significantly reduced urethane-induced oxidative stress. A protective effect against DNA damage was associated with the modulation of lipid peroxidation and low protein and gene expression of nitric oxide synthase. These findings suggest that the intake of pequi fruit might protect against in vivo genotoxicity and oxidative stress.
DOI: 10.6084/m9.figshare.7899152.v1
title: Elderly care: performance of interventions carried out by More Doctors Program professionals

description: ABSTRACT In order to assess coverage and quality of elderly care, a cross-sectional study of 204 interventions of Family Health Specialization students of UFPel was conducted, both connected and not connected to the More Doctors Program (PMM). The coverage difference between the third and first months of intervention and the percentage at the end of the third month were calculated in order to obtain quality indicators. An average increase in coverage of 35.7 percentage points (pp) (32.9, 38.6) was found: 42.1 pp (38.6, 45.7) and 26.1 pp (22.3, 30) were, respectively, related and not related to PMM. Brief Multidimensional Assessment (AMR), up-to-date clinical examination and assessment of the need for dental treatment showed better results in interventions conducted by PMM professionals. The interventions were effective regardless of supply and nationality, obtaining significantly better results those conducted by PMM professionals, especially Cubans.
DOI: 10.6084/m9.figshare.7899155.v1
title: A methodology to determine size and shape of plots for sugarcane plantation

description: ABSTRACT: Brazil is the largest sugarcane producer in the world and the leader in the production of sugar and ethanol. Although sugarcane has become an important factor in the Brazilian economy, cultivation has presented many issues, for example, the problems due to burning before the manual harvest. The Brazilian authorities have approved a law that prohibits this practice and mechanized harvesting has thus become the most fitting approach. Given this development, areas for sugarcane plantation must be properly rebuilt to accommodate the new way of harvesting. The main characteristic demanded of sugarcane plots to use harvesting machines is that they must be rectangular. In the present paper, we propose a methodology for dividing the plantation area into plots and planning their allocation so as to accommodate mechanized harvesting. In view of the requirement for plots to be rectangular, we represented this problem as a two-dimensional cutting problem, and to find a solution we adopted the AND/OR graph approach. The computational experiments were conducted using real cases, and the proposed strategy was shown to perform well.
DOI: 10.6084/m9.figshare.7899161.v1
title: Theoretical Study of Plasmonically Induced Transparency Effect in Arrays of Graphene-Based Double Disk Resonators

description: Abstract In this paper, we consider coupled disk-shaped resonators separated by a thin dielectric substrate that can be used as frequency-tunable filters or as electromagnetic switches in the terahertz frequency band. The two disks are electromagnetically coupled and resonate with dipole plasmonic modes. By using a Temporal Coupled-Mode Theory based approach, we show how to analytically calculate the frequency response of such structures.The analytical results are in good agreement with those obtained from computational simulations based on the finite element method.
DOI: 10.6084/m9.figshare.7899137
title: ROOTS OF MINI-CUTTING OF CLONES OF SEQUOIA SEMPERVIRENS IN DIFFERENT SEASONS OF THE YEAR

description: ABSTRACT We analyzed the rooting of sequoia mini-cuttings from different clones in the four seasons of the year and the use of the logistic model to estimate the time of maximization of rooting in each factor of analysis. Mini-cuttings of five clones grown in clonal mini-garden were placed to root in mini-tunnel in four seasons of the year. Weekly evaluations were performed (from 30 to 93 days) of these variables: survival (%), rooted mini-cuttings (%) and a number of emitted roots. These data were used to adjust the original logistic function. The experiment was set in completely randomized design, in a factorial scheme of 5 (clones) x 4 (seasons), using five replicates of 50 mini-cuttings per experimental unit. During the winter the lowest rooting of mini-cuttings was achieved (85%), with rates higher than 90% in other seasons. In winter, slower rooting also occurred, around 60-70 days, while in other seasons it was between 50-60 days after mini-cutting planting. The rooting process is dependent on the clones. Our data showed that four clones presented rooting greater than 90% and one less than 70%. In general, mini-cuttings can be performed at any time of the year, recommending the period of 90 days in mini-tunnel.
DOI: 10.6084/m9.figshare.7899140
title: Evaluation of nitrate adsorption from aqueous medium using modified montmorillonites

description: ABSTRACT This study investigated the efficiency of nitrate removal in aqueous medium using adsorption on commercial montmorillonites compared to an anionic resin widely used in this operation. Some of these clays were intercalated with hexadecyltrimethylammonium ion for this investigation. Specific surface areas, cation exchange capacities and mid-infrared spectra were determined for clays characterization. Preliminary tests indicated that the nanoclay functionalized with aminopropyltriethoxysilane and octadecylamine was the most efficient in nitrate adsorption, although it did not exceed anionic resin in efficiency. Adsorption kinetic and equilibrium of nitrate from aqueous phase on the nanoclay and anionic resin were determined and modeled for comparison, as well as for the selection of representative models and estimation of thermodynamic properties of the studied systems. All experiments were carried out at 25°C and at pH 7. Equilibrium isotherms were also determined at 35 and 45°C. The obtained results show that the adsorption processes studied are physical, spontaneous and favorable for both the resin and the nanoclay, which have very good affinity with nitrate. The most representative models for the systems were the pseudo-second order kinetic model and the Freundlich equilibrium isotherm.
DOI: 10.6084/m9.figshare.7899146
title: An ontogenic study of the behavioral effects of chronic intermittent exposure to ayahuasca in mice

description: Ayahuasca is a beverage obtained from decoctions of the Banisteriopsis caapi plus Psychotria viridis. In religious contexts, ayahuasca is used by different age groups. However, little is known of the effects of ayahuasca during ontogenic development, particularly with regard to the functional characteristics of the central nervous system. Animal models are useful for studying the ontogenic effects of ayahuasca because they allow exclusion of the behavioral influence associated with the ritualistic use. We investigated the effects of exposure to ayahuasca (1.5 mL/kg, orally, twice a week) on memory and anxiety in C57BL/6 mice, with the post-natal day (PND) being used as the ontogenic criterion for classification: childhood (PND21 to PND35), adolescence (PND35 to PND63), adulthood (PND90-PND118), childhood-adolescence (PND21 to PND63), childhood-adulthood (PND21 to PND118) and adolescence-adulthood (PND35 to PND118). One day after the last ayahuasca exposure, the mice were subjected to the Morris water maze (MWM), open field and elevated plus maze tasks (EPM). Ayahuasca did not affect locomotion in the open field or open arms exploration in the EPM, but increased the risk assessment behavior in the childhood group. Ayahuasca did not cause any change in acquisition of spatial reference memory in the MWM task, but decreased the time spent on the platform quadrant during the test session in the adolescence group. These results suggest that, in mice, exposure to ayahuasca in childhood and adolescence promoted anxiety and memory impairment, respectively. However, these behavioral changes were not long-lasting since they were not observed in the childhood-adulthood and adolescence-adulthood groups.
DOI: 10.6084/m9.figshare.7899137.v1
title: ROOTS OF MINI-CUTTING OF CLONES OF SEQUOIA SEMPERVIRENS IN DIFFERENT SEASONS OF THE YEAR

description: ABSTRACT We analyzed the rooting of sequoia mini-cuttings from different clones in the four seasons of the year and the use of the logistic model to estimate the time of maximization of rooting in each factor of analysis. Mini-cuttings of five clones grown in clonal mini-garden were placed to root in mini-tunnel in four seasons of the year. Weekly evaluations were performed (from 30 to 93 days) of these variables: survival (%), rooted mini-cuttings (%) and a number of emitted roots. These data were used to adjust the original logistic function. The experiment was set in completely randomized design, in a factorial scheme of 5 (clones) x 4 (seasons), using five replicates of 50 mini-cuttings per experimental unit. During the winter the lowest rooting of mini-cuttings was achieved (85%), with rates higher than 90% in other seasons. In winter, slower rooting also occurred, around 60-70 days, while in other seasons it was between 50-60 days after mini-cutting planting. The rooting process is dependent on the clones. Our data showed that four clones presented rooting greater than 90% and one less than 70%. In general, mini-cuttings can be performed at any time of the year, recommending the period of 90 days in mini-tunnel.
DOI: 10.6084/m9.figshare.7899143
title: Life cycle assessment of Municipal Construction and Demolition Waste Management System of Campinas Metropolitan Region

description: ABSTRACT The absence or inefficiency of Municipal Construction and Demolition Waste Management Systems (MCDWMS) may cause environmental impacts, which need a systematic evaluation, considering the local reality. There are few studies on the environmental impacts’ quantification of construction and demolition waste (CDW) management. Thus, in this work, MCDWMS’ environmental performance of the municipalities in the metropolitan region of Campinas was evaluated based on the life cycle assessment (LCA) methodology. The LCA study was modeled using the SimaPro 8.2.0, and the environmental impacts were evaluated by the CML baseline 2000 method, considering the categories of global warming, human toxicity, photochemical oxidation, acidification and eutrophication. When comparing the current environmental performance with the scenario that includes a recycling rate of 70% of CDW Class A (goal established in the Solid Waste Plan of São Paulo State), the environmental impacts were reduced in 22%. However, when analyzing the scenarios individually for each municipality, it was verified that due to the transport distances, some municipalities did not present environmental benefits resulting from recycling. These results demonstrate that recycling should not be the first option in the MCDWMS, and that the adoption of source reduction and reuse of waste within the scope of CDW management is urgent. These results may support the decision-making process in CDW management systems, as currently many Brazilian municipalities are planning the implementation of recycling facilities.
DOI: 10.6084/m9.figshare.7899146.v1
title: An ontogenic study of the behavioral effects of chronic intermittent exposure to ayahuasca in mice

description: Ayahuasca is a beverage obtained from decoctions of the Banisteriopsis caapi plus Psychotria viridis. In religious contexts, ayahuasca is used by different age groups. However, little is known of the effects of ayahuasca during ontogenic development, particularly with regard to the functional characteristics of the central nervous system. Animal models are useful for studying the ontogenic effects of ayahuasca because they allow exclusion of the behavioral influence associated with the ritualistic use. We investigated the effects of exposure to ayahuasca (1.5 mL/kg, orally, twice a week) on memory and anxiety in C57BL/6 mice, with the post-natal day (PND) being used as the ontogenic criterion for classification: childhood (PND21 to PND35), adolescence (PND35 to PND63), adulthood (PND90-PND118), childhood-adolescence (PND21 to PND63), childhood-adulthood (PND21 to PND118) and adolescence-adulthood (PND35 to PND118). One day after the last ayahuasca exposure, the mice were subjected to the Morris water maze (MWM), open field and elevated plus maze tasks (EPM). Ayahuasca did not affect locomotion in the open field or open arms exploration in the EPM, but increased the risk assessment behavior in the childhood group. Ayahuasca did not cause any change in acquisition of spatial reference memory in the MWM task, but decreased the time spent on the platform quadrant during the test session in the adolescence group. These results suggest that, in mice, exposure to ayahuasca in childhood and adolescence promoted anxiety and memory impairment, respectively. However, these behavioral changes were not long-lasting since they were not observed in the childhood-adulthood and adolescence-adulthood groups.