cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.4635935
title: Raw Data for the article: Novel swine biliary dilatation model with temperature-controlled endobiliary radiofrequency ablation: An effective tool for training in EUS-guided biliary drainage

description: <strong>Background and objectives: </strong>EUS-guided biliary drainage (EUS-BD) is used as a rescue method after failed endoscopic retrograde cholangiography. However, it is considered a technically challenging procedure. Phantoms and ex vivo biliary dilatation models have been used to enhance the learning of EUS-BD, but they provide a limited level of realism. The aim of this study was to develop a swine biliary dilatation model that uses temperature-controlled endobiliary radiofrequency ablation (EB-RFA) for training in EUS-BD. <strong>Materials and methods: </strong>Target temperature-controlled (80°C at 7 or 10 W for 60-120 s) EB-RFA was performed on seven pigs. Two weeks after the EB-RFA, EUS examination was performed to confirm biliary dilatation, and EUS-BD was then attempted by performing a hepaticogastrostomy (HGS) or cholecystogastrostomy (CGS). <strong>Results: </strong>Twelve sessions of EB-RFA (11 at the distal common bile duct [CBD] and one at the proximal CBD) were successfully performed on the seven pigs. There were no immediate postprocedural adverse events. Two weeks after the procedures, clinical signs of jaundice were observed in all the pigs. EUS examination revealed massive intrahepatic and extrahepatic biliary dilatations in all the pigs, and EUS-BD was attempted in the same session. HGS was performed on six pigs. Technical success was achieved in five of the six pigs (83.3%). Technical failure in HGS occurred during the stent deployment, and CGS was successfully performed on one pig. <strong>Conclusions: </strong>Our study shows that EB-RFA is an effective minimally invasive method for creating biliary dilatation models. It may be considered suitable for training in EUS-BD.
DOI: 10.5281/zenodo.4635934
title: Raw Data for the article: Novel swine biliary dilatation model with temperature-controlled endobiliary radiofrequency ablation: An effective tool for training in EUS-guided biliary drainage

description: <strong>Background and objectives: </strong>EUS-guided biliary drainage (EUS-BD) is used as a rescue method after failed endoscopic retrograde cholangiography. However, it is considered a technically challenging procedure. Phantoms and ex vivo biliary dilatation models have been used to enhance the learning of EUS-BD, but they provide a limited level of realism. The aim of this study was to develop a swine biliary dilatation model that uses temperature-controlled endobiliary radiofrequency ablation (EB-RFA) for training in EUS-BD. <strong>Materials and methods: </strong>Target temperature-controlled (80°C at 7 or 10 W for 60-120 s) EB-RFA was performed on seven pigs. Two weeks after the EB-RFA, EUS examination was performed to confirm biliary dilatation, and EUS-BD was then attempted by performing a hepaticogastrostomy (HGS) or cholecystogastrostomy (CGS). <strong>Results: </strong>Twelve sessions of EB-RFA (11 at the distal common bile duct [CBD] and one at the proximal CBD) were successfully performed on the seven pigs. There were no immediate postprocedural adverse events. Two weeks after the procedures, clinical signs of jaundice were observed in all the pigs. EUS examination revealed massive intrahepatic and extrahepatic biliary dilatations in all the pigs, and EUS-BD was attempted in the same session. HGS was performed on six pigs. Technical success was achieved in five of the six pigs (83.3%). Technical failure in HGS occurred during the stent deployment, and CGS was successfully performed on one pig. <strong>Conclusions: </strong>Our study shows that EB-RFA is an effective minimally invasive method for creating biliary dilatation models. It may be considered suitable for training in EUS-BD.
DOI: 10.5281/zenodo.4636026
title: Raw Data for the article: The impact of Centre's heart transplant status and volume on in-hospital outcomes following extracorporeal membrane oxygenation for refractory post-cardiotomy cardiogenic shock: a meta-analysis

description: <strong>Background: </strong>Postcardiotomy cardiogenic shock (PCS) that is refractory to inotropic support remains a major concern in cardiac surgery and is almost universally fatal unless treated with mechanical support. While reported mortality rates on ECMO vary from center to center, aim of the current report is assess if the outcomes differ between centres according to volume and heart transplantation status. <strong>Methods: </strong>A systematic search was performed according to PRISMA statement using PubMed/Medline databases between 2010 and 2018. Relevant articles were scrutinized and included in the meta-analysis only if reporting in-hospital/30-day mortality and heart transplantation status of the centre. Paediatric and congenital heart surgery-related studies along with those conducted in the setting of veno-venous ECMO for respiratory distress syndrome were excluded. Differences were assessed by means of subgroup meta-analysis and meta-regression. <strong>Results: </strong>Fifty-four studies enrolling N = 4421 ECMO patients were included. Of those, 6 series were performed in non-HTx centres (204 pts.;4.6%). Overall 30-day survival (95% Confidence Intervals) was 35.3% (32.5-38.2%) and did not statistically differ between non-HTx: 33.3% (26.8-40.4%) and HTx centres: 35.7% (32.7-38.8%); P<sub>interaction</sub> = 0.531. There was no impact of centre volume on survival as well: ß<sub>coef</sub> = 0.0006; P = 0.833. No statistical differences were seen between HTx and non-HTx with respect to ECMO duration, limb complications, reoperations for bleeding, kidney injury and sepsis. There were however significantly less neurological complications in the HTx as compared to non-HTx centres: 11.9% vs 19.5% respectively; P = 0.009; an inverse relationship was seen for neurologic complications in centres performing more ECMOs annually ß<sub>coef</sub> = - 0.0066; P = 0.031. Weaning rates and bridging to HTx and/or VADs were higher in HTx facilities. <strong>Conclusions: </strong>There was no apparent difference in survival after ECMO implantation for refractory PCS according to centre's ECMO volume and transplantation status. Potentially different risk profiles of patients in these centres must be taken account for before definite conclusions are drawn.
DOI: 10.5281/zenodo.4636025
title: Raw Data for the article: The impact of Centre's heart transplant status and volume on in-hospital outcomes following extracorporeal membrane oxygenation for refractory post-cardiotomy cardiogenic shock: a meta-analysis

description: <strong>Background: </strong>Postcardiotomy cardiogenic shock (PCS) that is refractory to inotropic support remains a major concern in cardiac surgery and is almost universally fatal unless treated with mechanical support. While reported mortality rates on ECMO vary from center to center, aim of the current report is assess if the outcomes differ between centres according to volume and heart transplantation status. <strong>Methods: </strong>A systematic search was performed according to PRISMA statement using PubMed/Medline databases between 2010 and 2018. Relevant articles were scrutinized and included in the meta-analysis only if reporting in-hospital/30-day mortality and heart transplantation status of the centre. Paediatric and congenital heart surgery-related studies along with those conducted in the setting of veno-venous ECMO for respiratory distress syndrome were excluded. Differences were assessed by means of subgroup meta-analysis and meta-regression. <strong>Results: </strong>Fifty-four studies enrolling N = 4421 ECMO patients were included. Of those, 6 series were performed in non-HTx centres (204 pts.;4.6%). Overall 30-day survival (95% Confidence Intervals) was 35.3% (32.5-38.2%) and did not statistically differ between non-HTx: 33.3% (26.8-40.4%) and HTx centres: 35.7% (32.7-38.8%); P<sub>interaction</sub> = 0.531. There was no impact of centre volume on survival as well: ß<sub>coef</sub> = 0.0006; P = 0.833. No statistical differences were seen between HTx and non-HTx with respect to ECMO duration, limb complications, reoperations for bleeding, kidney injury and sepsis. There were however significantly less neurological complications in the HTx as compared to non-HTx centres: 11.9% vs 19.5% respectively; P = 0.009; an inverse relationship was seen for neurologic complications in centres performing more ECMOs annually ß<sub>coef</sub> = - 0.0066; P = 0.031. Weaning rates and bridging to HTx and/or VADs were higher in HTx facilities. <strong>Conclusions: </strong>There was no apparent difference in survival after ECMO implantation for refractory PCS according to centre's ECMO volume and transplantation status. Potentially different risk profiles of patients in these centres must be taken account for before definite conclusions are drawn.
DOI: 10.5281/zenodo.6259390
title: msd-errors - Random walk data

description: The data related to the random walk components of the msd-error work, including truly random and temporarily anti-correlated random walks at a series of system and step size. These have either be analysed numerically or analytically (using kinisi, WLS, or OLS).<br><br>Created using showyourwork from this GitHub repo.<br>
DOI: 10.5281/zenodo.4636120
title: Raw Data for the article: Veno-Arterial Extracorporeal Life Support in Heart Transplant and Ventricle Assist Device Centres. Meta-analysis

description: <strong>Aims: </strong>Because reported mortality on veno-arterial (V-A) extracorporeal life support (ECLS) substantially varies between centres, the aim of the current analysis was to assess the outcomes between units performing heart transplantation and/or implanting ventricular assist device (HTx/VAD) vs. non-HTx/VAD units in patients undergoing V-A ECLS for cardiogenic shock. <strong>Methods and results: </strong>Systematic search according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses was performed using PubMed/MEDLINE databases until 30 November 2019. Articles reporting in-hospital/30-day mortality and centre's HTx/VAD status were included. In-hospital outcomes and long-term survival were analysed in subgroup meta-analysis. A total of 174 studies enrolling n = 13 308 patients were included with 20 series performed in non-HTx/VAD centres (1016 patients, 7.8%). Majority of patients underwent V-A ECLS for post-cardiotomy shock (44.2%) and acute myocardial infarction (20.7%). Estimated overall in-hospital mortality was 57.2% (54.9-59.4%). Mortality rates were higher in non-HTx/VAD [65.5% (59.8-70.8%)] as compared with HTx/VAD centres [55.8% (53.3-58.2%)], P &lt; 0.001. Estimated late survival was 61.8% (55.7-67.9%) without differences between non-HTx/VAD and HTx/VAD centres: 66.5% (30.3-1.02%) vs. 61.7% (55.5-67.8%), respectively (P = 0.797). No differences were seen with respect to ECLS duration, limb complications, and reoperations for bleeding, kidney injury, and sepsis. Yet, weaning rates were higher in HTx/VAD vs. non-HTx/VAD centres: 58.7% (56.2-61.1%) vs. 48.9% (42.0-55.9%), P = 0.010. Estimated rate of bridge to heart transplant was 6.6% (5.2-8.3%) with numerical, yet not statistically significant, difference between non-HTx/VAD [2.7% (0.8-8.3%)] as compared with HTx/VAD [6.7% (5.3-8.6%)] (P = 0.131). <strong>Conclusions: </strong>Survival after V-A ECLS differed according to centre's HTx/VAD status. Potentially different risk profiles of patients must be taken account for before definite conclusions are drawn.
DOI: 10.5281/zenodo.4636207
title: Raw Data for the article: Left Ventricle Unloading with Veno-Arterial Extracorporeal Membrane Oxygenation for Cardiogenic Shock. Systematic Review and Meta-Analysis

description: During veno-arterial extracorporeal membrane oxygenation (VA-ECMO), the increase of left ventricular (LV) afterload can potentially increase the LV stress, exacerbate myocardial ischemia and delay recovery from cardiogenic shock (CS). Several strategies of LV unloading have been proposed. Systematic review and meta-analysis in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement included adult patients from studies published between January 2000 and March 2019. The search was conducted through numerous databases. Overall, from 62 papers, 7581 patients were included, among whom 3337 (44.0%) received LV unloading concomitant to VA-ECMO. Overall, in-hospital mortality was 58.9% (4466/7581). A concomitant strategy of LV unloading as compared to ECMO alone was associated with 12% lower mortality risk (RR 0.88; 95% CI 0.82-0.93; <em>p</em> &lt; 0.0001; <em>I</em><sup>2</sup> = 40%) and 35% higher probability of weaning from ECMO (RR 1.35; 95% CI 1.21-1.51; <em>p</em> &lt; 0.00001; <em>I</em><sup>2</sup> = 38%). In an analysis stratified by setting, the highest mortality risk benefit was observed in case of acute myocardial infarction: RR 0.75; 95%CI 0.68-0.83; <em>p</em> &lt; 0.0001; <em>I</em><sup>2</sup> = 0%. There were no apparent differences between two techniques in terms of complications. In heterogeneous populations of critically ill adults in CS and supported with VA-ECMO, the adjunct of LV unloading is associated with lower early mortality and higher rate of weaning.
DOI: 10.5281/zenodo.4636206
title: Raw Data for the article: Left Ventricle Unloading with Veno-Arterial Extracorporeal Membrane Oxygenation for Cardiogenic Shock. Systematic Review and Meta-Analysis

description: During veno-arterial extracorporeal membrane oxygenation (VA-ECMO), the increase of left ventricular (LV) afterload can potentially increase the LV stress, exacerbate myocardial ischemia and delay recovery from cardiogenic shock (CS). Several strategies of LV unloading have been proposed. Systematic review and meta-analysis in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement included adult patients from studies published between January 2000 and March 2019. The search was conducted through numerous databases. Overall, from 62 papers, 7581 patients were included, among whom 3337 (44.0%) received LV unloading concomitant to VA-ECMO. Overall, in-hospital mortality was 58.9% (4466/7581). A concomitant strategy of LV unloading as compared to ECMO alone was associated with 12% lower mortality risk (RR 0.88; 95% CI 0.82-0.93; <em>p</em> &lt; 0.0001; <em>I</em><sup>2</sup> = 40%) and 35% higher probability of weaning from ECMO (RR 1.35; 95% CI 1.21-1.51; <em>p</em> &lt; 0.00001; <em>I</em><sup>2</sup> = 38%). In an analysis stratified by setting, the highest mortality risk benefit was observed in case of acute myocardial infarction: RR 0.75; 95%CI 0.68-0.83; <em>p</em> &lt; 0.0001; <em>I</em><sup>2</sup> = 0%. There were no apparent differences between two techniques in terms of complications. In heterogeneous populations of critically ill adults in CS and supported with VA-ECMO, the adjunct of LV unloading is associated with lower early mortality and higher rate of weaning.
DOI: 10.6084/m9.figshare.7964666
title: Code and data for "A latitudinal signal in the relationship between species geographic range size and climatic niche area"

description: Code and data to reproduce the analyses from:<br>&gt; Dallas, TA "A latitudinal signal in the relationship between species geographic range size and climatic niche area"<br>Please cite the original data sources for the species trait and occurrence data. Information and citations provided in the article text, and within the analysis code (`dallas2021.Rmd')
DOI: 10.6084/m9.figshare.7964666.v3
title: Code and data for "A latitudinal signal in the relationship between species geographic range size and climatic niche area"

description: Code and data to reproduce the analyses from:<br>&gt; Dallas, TA "A latitudinal signal in the relationship between species geographic range size and climatic niche area"<br>Please cite the original data sources for the species trait and occurrence data. Information and citations provided in the article text, and within the analysis code (`dallas2021.Rmd')
DOI: 10.6084/m9.figshare.7964666.v2
title: Code and data for "A latitudinal signal in the relationship between species geographic range size and climatic niche area"

description: Code and data to reproduce the analyses from:<br>&gt; Dallas, TA "A latitudinal signal in the relationship between species geographic range size and climatic niche area"<br>Please cite the original data sources for the species trait and occurrence data. Information and citations provided in the article text, and within the analysis code (`dallas2021.Rmd')
DOI: 10.5281/zenodo.6256759
title: Raw data for "Corticomuscular and Intermuscular Coupling in Simple Hand Movements to Enable a Hybrid Brain-Computer Interface": unpublished figures and source data.

description: Figures 1-4: Selected features (EEG-EMG and EMG-EMG couples) for movement vs rest classification (Ext R and L, Gra R and L). Figure 5: Distribution of Gra vs Ext classification among bands. Source data.
DOI: 10.5281/zenodo.6256758
title: Raw data for "Corticomuscular and Intermuscular Coupling in Simple Hand Movements to Enable a Hybrid Brain-Computer Interface": unpublished figures and source data.

description: Figures 1-4: Selected features (EEG-EMG and EMG-EMG couples) for movement vs rest classification (Ext R and L, Gra R and L). Figure 5: Distribution of Gra vs Ext classification among bands. Source data.
DOI: 10.17632/495z7s99zs.1
title: Proteomics and phosphoproteomics datasets of a muscle-specific STIM1 loss-of-function mouse model.

description: STIM1 is an ER/SR transmembrane protein that interacts with ORAI1 to activate store operated Ca2+ entry (SOCE) upon ER/SR depletion of calcium. Normally highly expressed in skeletal muscle, STIM1 deficiency causes significant changes to mitochondrial ultrastructure that do not occur with loss of ORAI1 or other components of SOCE. The datasets in this article are from large-scale proteomics and phosphoproteomics experiments in an inducible mouse model of skeletal muscle-specific STIM1 knock out (KO). These data reveal statistically significant changes in the relative abundance of specific proteins and sites of protein phosphorylation in STIM1 KO gastrocnemius. Protein samples from five biological replicates of each condition (+/- STIM1) were enzymatically digested, the resulting peptides labeled with tandem mass tag (TMT) reagents, mixed, and fractionated.  Phosphopeptides were enriched and a small amount of each input retained for protein abundance analysis. All phosphopeptide and input fractions were analyzed by nano LC-MS/MS on a Q Exactive Plus Orbitrap mass spectrometer, searched with Proteome Discoverer software, and processed with in-house R-scripts for data normalization and statistical analysis.
DOI: 10.17632/nzvxy6pvdj.1
title: H2S and PSSH Microscopy images for Statzer et al, Nat Comm, 2022

description: Original microscopy images used for making Figures 4g, 5b&c and 7e&f.
DOI: 10.17632/yxp9z5zz24.1
title: Data for: High-resolution-palynology signals in the surface sediments of coastal Hainan Island of China

description: Raw data for pollen and spore count from 318 marine surface sediment samples collected from south and southeastern Hainan Island coastal-shelf. Dry sample weight and preservation conditions were also provided.
DOI: 10.17632/34znc6vj9m.2
title: Skin Cancer Transportation Barriers to Healthcare - Supplement

description: Supplemental materials for manuscript "Prevalence and predictors of transportation barriers to healthcare among U.S. adults with a history of skin cancer"
DOI: 10.17632/cvz9xdtwd2.2
title: The influence of shifting perspective on episodic and semantic details during autobiographical memory recall

description: Summary data of the effects of shifting perspective on autobiographical memory narratives and subjective ratings.
DOI: 10.17632/wr9wsvjkh3.1
title: LINF_230005800

description: protein of unknown function - conserved
Leishmania infantum (strain JPCM5)
DOI: 10.17632/8gb2w6wstt.1
title: LINF_230006100

description: GDP-mannose pyrophosphorylase | GDPMP
Leishmania infantum (strain JPCM5)
DOI: 10.17632/5trrm2j2dd.1
title: LINF_230006300

description: cyclophilin 3 | CyP3
Leishmania infantum (strain JPCM5)
DOI: 10.17632/98p2vg7d5k.1
title: LINF_230006600

description: Leucine Rich repeat-containing protein
Leishmania infantum (strain JPCM5)
DOI: 10.17632/t67cwxrbks.1
title: LINF_230007100

description: endoribonuclease L-PSP (pb5)
Leishmania infantum (strain JPCM5)
DOI: 10.17632/jswyp7fbtm.1
title: LINF_230007200

description: ATP-binding cassette (ABC) protein | ABCC1
Leishmania infantum (strain JPCM5)
DOI: 10.17632/yyz7c5m77f.1
title: LINF_230007300

description: ATP-binding cassette (ABC) protein | ABCC2
Leishmania infantum (strain JPCM5)
DOI: 10.17632/zbksm23r8k.1
title: Preclinical evaluation of a precision medicine approach to DNA vaccination in Type 1 diabetes

description: The figures refer to the PNAS paper of the same title.
Blood glucose monitoring (Figures 1, 2, 3): Excel file compiling the incidence of diabetes in each group (Fig.1-2) and percentage of proliferated cells in each mouse (Fig.3).
Flow cytometry (Figures 4,5): Raw FCS files with explanatory Excel file for file naming and panels
Histopathology (Figure 6): Excel file compiling the scoring from two independent investigators, one blinded to the groups, averages per section, per mouse and per group. There are two tissue sections per slide, 3 slides per mouse (total 6 sections per mouse), and 5 mice per group. Image files are ~1Gb each and cannot be uploaded due to capacity limits.
DOI: 10.17632/2533hkj66b.1
title: Data in Batemans Bay (BB)

description: The field data and model results in BB.
DOI: 10.17632/8t8zgz6g39.1
title: Patient and Provider Satisfaction with Synchronous Teledermatology during the COVID-19 Pandemic: A Systematic Review

description: The following supplemental documents include the PRISMA Flow Diagram, PRISMA Checklist, and Satisfaction Score Criteria.
DOI: 10.17632/bkkpcbfb62.1
title: Supplementary Material for Genotype-Phenotype Correlations of Neurovascular Structures on the Feet in Pachyonychia Congenita: a cross-sectional study

description: Supplementary Table S1. Survey responses according to PC genotypes  

Supplementary Table S2a. Predictors of the ways NVS impact patients within PC-K16 mutations

Supplementary Table S2b. Predictors of the ways NVS impact patients within PC-K16 mutations (head domain)

Supplementary Table S3. Predictors of the ways NVS impact patients within PC-K6a mutations

Supplementary Table S4. Proportion of individuals within each PC genotype 

Supplementary Table S5. Presence of NVS within mutations in PC genotypes


Appendix 1. Survey

Appendix 2. Mutation analysis