cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5286/isis.e.rb2000181
title: ISTAN commissioning proposal

description: The ability to design new and more sophisticated apparatus capable of pushing the limits of experiments is necessary for progress. The team at Uppsala University in conjunction with partners at ISIS and Stockholm University, have designed and built a state-of-the-art magnetic suspension balance (MSB) for simultaneous thermogravimetric analysis (TGA) and neutron diffraction experiments. Based on the Rubotherm ISOSORP, it is capable of achieving a range of experimental conditions for TGA not yet seen on a neutron instrument. The IGAn currently available for TGA is limited in scope with the experimental conditions it can achieve. This is due in part to the design and the balance-by-wire mechanism it uses to weigh the samples. The new ancillary designed at Uppsala University is however, much more sophisticated and more capable than the existing IGAn.
DOI: 10.5286/isis.e.rb2000181-1
title: ISTAN commissioning proposal

description: The ability to design new and more sophisticated apparatus capable of pushing the limits of experiments is necessary for progress. The team at Uppsala University in conjunction with partners at ISIS and Stockholm University, have designed and built a state-of-the-art magnetic suspension balance (MSB) for simultaneous thermogravimetric analysis (TGA) and neutron diffraction experiments. Based on the Rubotherm ISOSORP, it is capable of achieving a range of experimental conditions for TGA not yet seen on a neutron instrument. The IGAn currently available for TGA is limited in scope with the experimental conditions it can achieve. This is due in part to the design and the balance-by-wire mechanism it uses to weigh the samples. The new ancillary designed at Uppsala University is however, much more sophisticated and more capable than the existing IGAn.
DOI: 10.5286/isis.e.rb2000205
title: Magnetic structure of frustrated quasi-one-dimensional spin-1/2 chain KVOPO4

description: We propose the low-temperature neutron diffraction experiment on a quantum magnet KVOPO4. This compound shows experimental signatures of spin chains with competing ferromagnetic and antiferromagnetic interactions and may have an unusual, canted antiferromagnetic ground state. The proposed neutron experiment will elucidate the magnetic structure of KVOPO4 and assist in constructing a general microscopic picture of this interesting compound.
DOI: 10.5286/isis.e.rb2000205-1
title: Magnetic structure of frustrated quasi-one-dimensional spin-1/2 chain KVOPO4

description: We propose the low-temperature neutron diffraction experiment on a quantum magnet KVOPO4. This compound shows experimental signatures of spin chains with competing ferromagnetic and antiferromagnetic interactions and may have an unusual, canted antiferromagnetic ground state. The proposed neutron experiment will elucidate the magnetic structure of KVOPO4 and assist in constructing a general microscopic picture of this interesting compound.
DOI: 10.5286/isis.e.rb2000234
title: The dynamics of water in halloysite

description: Water is ubiquitous on Earth, where its presence has shaped the planet and led to life. Halloysite is a clay mineral that is formed by water, holds water in its structure and can subsequently lose water. Therefore, where we find halloysite in nature, we can also find a story of how water was taken up and expelled by the planet. This knowledge can feed into the global water cycle and be useful in agriculture; halloysite is found in soils where the uptake of water can be vital for the nutrition of plants. This experiment aims to reveal how water molecules moves through halloysite by subjecting it to a beam of neutrons. Halloysite is made up of a one-molecule thick water layer, squeezed in between two layers of clay. This is a novel opportunity to study a two-dimensional water layer and will give atomic-level insight, on a water-mineral relationship that is consequential in nature.
DOI: 10.5286/isis.e.rb2000234-1
title: The dynamics of water in halloysite

description: Water is ubiquitous on Earth, where its presence has shaped the planet and led to life. Halloysite is a clay mineral that is formed by water, holds water in its structure and can subsequently lose water. Therefore, where we find halloysite in nature, we can also find a story of how water was taken up and expelled by the planet. This knowledge can feed into the global water cycle and be useful in agriculture; halloysite is found in soils where the uptake of water can be vital for the nutrition of plants. This experiment aims to reveal how water molecules moves through halloysite by subjecting it to a beam of neutrons. Halloysite is made up of a one-molecule thick water layer, squeezed in between two layers of clay. This is a novel opportunity to study a two-dimensional water layer and will give atomic-level insight, on a water-mineral relationship that is consequential in nature.
DOI: 10.17632/wfy6p6dbdd.1
title: Data for: Sequencing shorter cfDNA fragments improves the fetal DNA fraction in noninvasive prenatal testing

description: A total of 2817 plasma samples from pregnant women (1409 male and 1408 female fetuses) were collected at a single prenatal diagnostic center between October 2015 and July 2018. The mean age, BMI, and gestational age of pregnant women were 30.6 years (range 18-49 years), 22.4 kg/m2 (range 14.9-44.2 kg/m2), and 17.4 weeks (range 12-27 weeks)
DOI: 10.5286/isis.e.rb2010015
title: PROBING WATER DYNAMICS IN HEALTHY AND CANCER HUMAN TISSUE BY QENS

description: Normal-to-malignant transformation, still an ill-understood process, is related to the biomechanical properties of cells within tissues, which are strongly dependent on the dynamical behaviour of interfacial water. This is known to play a fundamental role in normal cellular activity, namely through maintenance of the three-dimensional architecture and functional conformation of biopolymers.Building on the success of previous QENS and INS experiments on intracellular water in human cancer and non-tumorigenic cells [1-4], the present study aims to apply QENS for probing interfacial water dynamics in healthy and cancer human tissue. This is an innovative approach for identifying particular features associated to malignancy that may allow a better understanding of the normal-to-cancer transition thus contributing to improved cancer diagnosis methods and chemotherapeutic approaches.
DOI: 10.5286/isis.e.rb2010015-1
title: PROBING WATER DYNAMICS IN HEALTHY AND CANCER HUMAN TISSUE BY QENS

description: Normal-to-malignant transformation, still an ill-understood process, is related to the biomechanical properties of cells within tissues, which are strongly dependent on the dynamical behaviour of interfacial water. This is known to play a fundamental role in normal cellular activity, namely through maintenance of the three-dimensional architecture and functional conformation of biopolymers.Building on the success of previous QENS and INS experiments on intracellular water in human cancer and non-tumorigenic cells [1-4], the present study aims to apply QENS for probing interfacial water dynamics in healthy and cancer human tissue. This is an innovative approach for identifying particular features associated to malignancy that may allow a better understanding of the normal-to-cancer transition thus contributing to improved cancer diagnosis methods and chemotherapeutic approaches.
DOI: 10.5286/isis.e.rb2000231
title: Investigation of magnetic structure in the polar magnetic oxides LuMWO6 (M = Fe, Cr)

description: Magnetoelectric multiferroics, materials in which magnetic and electric orders coexist and coupled to each other, have drawn tremendous interest in condensed matter physics due to their fundamental physics and promising applications in future storage devices. Along this line, we have discovered a new magnetoelectric multiferroic material LuFeWO6. However, we did not observe multiferroicity in the isostructural compound LuCrWO6. Both the compounds crystallize in polar orthorhombic structure and exhibit long-range magnetic ordering of Fe3+- and Cr3+ ions at TN = 11.8 K and 19.2 K, respectively. LuFeWO6 shows a change in electric polarization at TN demonstrating the magnetoelectric multiferroicity. Therefore, we need knowledge of the magnetic structure to understand the origin of multiferroicity in LuFeWO6 and the absence of the same in LuCrWO6.
DOI: 10.5286/isis.e.rb2000231-1
title: Investigation of magnetic structure in the polar magnetic oxides LuMWO6 (M = Fe, Cr)

description: Magnetoelectric multiferroics, materials in which magnetic and electric orders coexist and coupled to each other, have drawn tremendous interest in condensed matter physics due to their fundamental physics and promising applications in future storage devices. Along this line, we have discovered a new magnetoelectric multiferroic material LuFeWO6. However, we did not observe multiferroicity in the isostructural compound LuCrWO6. Both the compounds crystallize in polar orthorhombic structure and exhibit long-range magnetic ordering of Fe3+- and Cr3+ ions at TN = 11.8 K and 19.2 K, respectively. LuFeWO6 shows a change in electric polarization at TN demonstrating the magnetoelectric multiferroicity. Therefore, we need knowledge of the magnetic structure to understand the origin of multiferroicity in LuFeWO6 and the absence of the same in LuCrWO6.
DOI: 10.5286/isis.e.rb2010109
title: Two-dimensional magnetism in the Cu-containing planes of metatorbenite

description: Advances in coordination chemistry have led to the discovery of new architectures which can be described by different model magnetic systems. Here we focus on metatorbenite, a mineral with a crystal structure which consists of alternating layers of (1) uranyl phosphate and (2) a network of spin-1/2 Cu2+ ions linked by a hydrogen-bonded network of water. The diamagnetic uranyl phosphate layers serve to effectively magnetically insulate the magnetic layers, meaning that this compound is expected to be a model two-dimensional Heisenberg square-lattice antiferromagnet. To estimate the inter-sheet coupling J' it is important to measure the Neel temperature, but this is difficult to do with bulk techniques since the system is so anisotropic; it is well-known that muons, on the other hand, are ideally suited to detecting magnetic order in highly anisotropic systems.
DOI: 10.5286/isis.e.rb2010109-1
title: Two-dimensional magnetism in the Cu-containing planes of metatorbenite

description: Advances in coordination chemistry have led to the discovery of new architectures which can be described by different model magnetic systems. Here we focus on metatorbenite, a mineral with a crystal structure which consists of alternating layers of (1) uranyl phosphate and (2) a network of spin-1/2 Cu2+ ions linked by a hydrogen-bonded network of water. The diamagnetic uranyl phosphate layers serve to effectively magnetically insulate the magnetic layers, meaning that this compound is expected to be a model two-dimensional Heisenberg square-lattice antiferromagnet. To estimate the inter-sheet coupling J' it is important to measure the Neel temperature, but this is difficult to do with bulk techniques since the system is so anisotropic; it is well-known that muons, on the other hand, are ideally suited to detecting magnetic order in highly anisotropic systems.
DOI: 10.5286/isis.e.rb2000241
title: [NCNR/NIST] Depth-profiling magnetic behavior at Weyl Mn3Ge/ferromagnet interfaces

description: In the proposed experiments, we will use PNR to elucidate exchange coupling at Mn3Ge/FM heterointerfaces. In doing so, we will address the following fundamental questions: Does the adjacent ferromagnet induce a magnetization within Mn3+δGe? Does the presence of Mn3+δGe suppress magnetism with the ferromagnetic layer at the interface? How does the composition of the Mn3+δGe film impact the interfacial magnetism? The proposed experiments will be complemented by measurements of the spin Hall effect to provide a detailed understanding on how the interfacial magnetic profile impacts the spin-orbit torques in these heterostructures.
DOI: 10.17632/8ndj4hdxnn.1
title: Data for: The continuing burden of Rh disease, 50 years after the introduction of anti-Rh(D) immunoglobin prophylaxis; A call to action

description: NO ADDITIONAL DATA SETS WITH THIS MANUSCRIPT. HOWEVER, AN INSTRUCTIVE VIDEO PRESENTATION HAS BEEN DEVELOPED AT COLUMBIA UNIVERSITY AND KEDRION INDUSTRY. THIS VIDEO WILL BE AVAILABLE TO ALL AJOG READER
DOI: 10.5286/isis.e.rb2000241-1
title: [NCNR/NIST] Depth-profiling magnetic behavior at Weyl Mn3Ge/ferromagnet interfaces

description: In the proposed experiments, we will use PNR to elucidate exchange coupling at Mn3Ge/FM heterointerfaces. In doing so, we will address the following fundamental questions: Does the adjacent ferromagnet induce a magnetization within Mn3+δGe? Does the presence of Mn3+δGe suppress magnetism with the ferromagnetic layer at the interface? How does the composition of the Mn3+δGe film impact the interfacial magnetism? The proposed experiments will be complemented by measurements of the spin Hall effect to provide a detailed understanding on how the interfacial magnetic profile impacts the spin-orbit torques in these heterostructures.
DOI: 10.5286/isis.e.rb2010152-2
title: Plant Antimicrobial Protein Interactions with Self-Assembled Floating Membrane Models of Plant and Bacterial Membranes

description: Previously (RB1910140) we developed free floating model plant and pathogen membranes where complex unsaturated lipid mixtures and sterols which can be self-assembled adjacent to anionic PEGylated thiol self-assembling monolayers (SAM). Here, we will examine the interaction of plant defence protein purothionin, under physiologically accurate conditions using this sample system. Furthermore, we will examine whether this novel sample system has any particular issues relating to this kind of interaction studies and how the disruption of the floating bilayer affects the system behaviour. For our study we will generate four different membranes – two plant plasma membrane models of different complexity in their lipid composition and two bacterial models. The distribution of purothionin across each membrane, as well as the position and condition of each membrane itself will be elucidated.
DOI: 10.5286/isis.e.rb2000227
title: Neutron powder diffraction studies on quasi two-dimensional corrugated layered oxides Ba4Mn3O10 and Sr4Mn3O10

description: Ba4Mn3O10 and Sr4Mn3O10 crystallize in an orthorhombic crystal structure consisting of corrugated layers containing Mn3O12 polyhedra. The magnetic susceptibility consists of a broad hump-like feature around 180 K indicating the presence of low dimensional magnetic correlation. Recently, we studied the Ru counterpart, Ba4Ru3O10 using neutron scattering and muSR technique and observed the absence of any magnetic moment at one of the two Ru site which is found to be connected to the significant crystal-field effect. Inspired from this result we already performed inelastic neutron scattering on the proposed compounds. This observation clearly indicates that the orbital effect is playing a crucial role in Ba4Mn3O10 and Sr4Mn3O10. Hence, to explore the true magnetic structure is very important and necessary to understand the physics behind the complex magnetic ground state in these compounds.
DOI: 10.5286/isis.e.rb2000227-1
title: Neutron powder diffraction studies on quasi two-dimensional corrugated layered oxides Ba4Mn3O10 and Sr4Mn3O10

description: Ba4Mn3O10 and Sr4Mn3O10 crystallize in an orthorhombic crystal structure consisting of corrugated layers containing Mn3O12 polyhedra. The magnetic susceptibility consists of a broad hump-like feature around 180 K indicating the presence of low dimensional magnetic correlation. Recently, we studied the Ru counterpart, Ba4Ru3O10 using neutron scattering and muSR technique and observed the absence of any magnetic moment at one of the two Ru site which is found to be connected to the significant crystal-field effect. Inspired from this result we already performed inelastic neutron scattering on the proposed compounds. This observation clearly indicates that the orbital effect is playing a crucial role in Ba4Mn3O10 and Sr4Mn3O10. Hence, to explore the true magnetic structure is very important and necessary to understand the physics behind the complex magnetic ground state in these compounds.
DOI: 10.5286/isis.e.rb2010615
title: Controlled morphological transformation of polymer nanoparticles

description: The production of nanoparticles with well-defined shapes and dimensions is key to understanding their unique properties and tailoring them for specific applications. For example, we know that cylindrical nanoparticles interact with cells in a different way to spherical ones, and we would like to understand why in more detail so that we can design advanced medicines which use nanoparticles to deliver therapeutics to specific locations in the body, reducing side effects. We have been studying a method that allows the straightforward production of cylindrical nanoparticles with very well controlled lengths, which could allow these fundamental properties to be studied in much greater detail. Here, we will investigate how this 'morphological transformation' process works at the molecular level.
DOI: 10.5286/isis.e.rb2010615-1
title: Controlled morphological transformation of polymer nanoparticles

description: The production of nanoparticles with well-defined shapes and dimensions is key to understanding their unique properties and tailoring them for specific applications. For example, we know that cylindrical nanoparticles interact with cells in a different way to spherical ones, and we would like to understand why in more detail so that we can design advanced medicines which use nanoparticles to deliver therapeutics to specific locations in the body, reducing side effects. We have been studying a method that allows the straightforward production of cylindrical nanoparticles with very well controlled lengths, which could allow these fundamental properties to be studied in much greater detail. Here, we will investigate how this 'morphological transformation' process works at the molecular level.
DOI: 10.5286/isis.e.rb2010405
title: Transport of water in soft confinement

description: The project aims at establishing a new model to describe water transport in soft porous materials which accounts for coupling between adsorption, deformation and transport. In contrary to water transport in condensed matter, soft materials present much more complex processes and a complete picture of transport is lacking. We therefore propose to investigate water transport in polymers with intrinsic microporosity (PIM-1) under relevant conditions of mechanical stress and hydrostatics pressures. First, structural deformations of the polymer and of its microporosity (pore dimension &lt; 2 nm) in these conditions will be investigated (proposal submitted on NIMROD). Then, transport mechanisms at the microscopic scale will be investigated by quasi-elastic incoherent neutron scattering on IRIS. We request for these experiments 5 days on IRIS.
DOI: 10.5286/isis.e.rb2010405-1
title: Transport of water in soft confinement

description: The project aims at establishing a new model to describe water transport in soft porous materials which accounts for coupling between adsorption, deformation and transport. In contrary to water transport in condensed matter, soft materials present much more complex processes and a complete picture of transport is lacking. We therefore propose to investigate water transport in polymers with intrinsic microporosity (PIM-1) under relevant conditions of mechanical stress and hydrostatics pressures. First, structural deformations of the polymer and of its microporosity (pore dimension &lt; 2 nm) in these conditions will be investigated (proposal submitted on NIMROD). Then, transport mechanisms at the microscopic scale will be investigated by quasi-elastic incoherent neutron scattering on IRIS. We request for these experiments 5 days on IRIS.
DOI: 10.5286/isis.e.rb2010441
title: Short range magnetic order in the Ni48Mn36Sn16 Heusler compound

description: Ni2MnX (X=In,Sn,Ga...) Heuslers are a class of intermetallic compounds widely studied for their multifunctional properties. A deep understanding of the physical mechanisms that control their magnetic features, pivotal to design new materials with predictable properties, is not yet achieved. The aim of the present proposal is to investigate the presence of magnetic short-range correlations in the ferromagnetic austenitic phase of the Ni48Mn36Sn16 alloy through measurements of small angle neutron scattering. Indeed, neutron diffraction experiments, performed on the WISH diffractometer on the same alloy, showed an increase of diffuse scattering at low-Q by decreasing temperature. This fact suggests the presence in the material of short-range ferromagnetic correlations that could be due to nanometric inhomogeneities or to the complex interplay of different magnetic interactions.
DOI: 10.5286/isis.e.rb2010441-1
title: Short range magnetic order in the Ni48Mn36Sn16 Heusler compound

description: Ni2MnX (X=In,Sn,Ga...) Heuslers are a class of intermetallic compounds widely studied for their multifunctional properties. A deep understanding of the physical mechanisms that control their magnetic features, pivotal to design new materials with predictable properties, is not yet achieved. The aim of the present proposal is to investigate the presence of magnetic short-range correlations in the ferromagnetic austenitic phase of the Ni48Mn36Sn16 alloy through measurements of small angle neutron scattering. Indeed, neutron diffraction experiments, performed on the WISH diffractometer on the same alloy, showed an increase of diffuse scattering at low-Q by decreasing temperature. This fact suggests the presence in the material of short-range ferromagnetic correlations that could be due to nanometric inhomogeneities or to the complex interplay of different magnetic interactions.
DOI: 10.5286/isis.e.rb2000151
title: Field dependence of the incommensurate phase in Ca3Ru2O7

description: The layered perovskite ruthenates are a fascinating family of materials, in which electron correlations, distorted octahedral crystal fields and spin-orbit coupling combine to produce myriad electronic and magnetic phases. Bilayer Ca3Ru2O7 undergoes a coupled structural, electronic and magnetic transition at Ts = 48K. On recent experiments at WISH (RB1920210) and I16 at the Diamond Light Source, we discovered an incommensurate phase that appears in the vicinity of this transition. There is an outstanding question, however, regarding how this phase relates to satellite peaks previously seen in Ca3Ru2O7 under magnetic fields. Here we propose to resolve this question using single crystal neutron diffraction at WISH, allowing us to complete the dataset needed for a publication.
DOI: 10.17632/hjzfrhmvxm.1
title: Data for: Evaluation of Cerebral Oxygen Perfusion During Shoulder Arthroplasty Performed in the Semi-Beach Chair Position

description: Graphs provided by statistians after obtaining data from our machineless
DOI: 10.5286/isis.e.rb2000151-1
title: Field dependence of the incommensurate phase in Ca3Ru2O7

description: The layered perovskite ruthenates are a fascinating family of materials, in which electron correlations, distorted octahedral crystal fields and spin-orbit coupling combine to produce myriad electronic and magnetic phases. Bilayer Ca3Ru2O7 undergoes a coupled structural, electronic and magnetic transition at Ts = 48K. On recent experiments at WISH (RB1920210) and I16 at the Diamond Light Source, we discovered an incommensurate phase that appears in the vicinity of this transition. There is an outstanding question, however, regarding how this phase relates to satellite peaks previously seen in Ca3Ru2O7 under magnetic fields. Here we propose to resolve this question using single crystal neutron diffraction at WISH, allowing us to complete the dataset needed for a publication.