cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7488/ds/7664
title: Transmembrane protein 97 is a potential synaptic amyloid beta receptor in human Alzheimer’s disease

description: Data from Colom-Cadena et al Published in Acta Neuropathologica in 2024. Abstract: Synapse loss correlates with cognitive decline in Alzheimer’s disease, and soluble oligomeric amyloid beta (Aβ) is implicated in synaptic dysfunction and loss. An important knowledge gap is the lack of understanding of how Aβ leads to synapse degeneration. In particular, there has been difficulty in determining whether there is a synaptic receptor that binds Aβ and mediates toxicity. While many candidates have been observed in model systems, their relevance to human AD brain remains unknown. This is in part due to methodological limitations preventing visualization of Aβ binding at individual synapses. To overcome this limitation, we combined two high resolution microscopy techniques: array tomography and Förster resonance energy transfer (FRET) to image over 1 million individual synaptic terminals in temporal cortex from AD (n=11) and control cases (n=9). Within presynapses and postsynaptic densities, oligomeric Aβ generates a FRET signal with transmembrane protein 97. Further, amyloid beta generates a FRET signal with cellular prion protein, and postsynaptic density 95 within postsynapses. Transmembrane protein 97 is also present in a higher proportion of postsynapses in Alzheimer’s brain compared to controls. We inhibited Aβ / transmembrane protein 97 interaction in a mouse model of amyloidopathy by treating with the allosteric modulator CT1812. CT1812 drug concentration correlated negatively with synaptic FRET signal between transmembrane protein 97 and Aβ. In human induced pluripotent stem cell derived neurons, transmembrane protein 97 is present in synapses and colocalizes with Aβ when neurons are challenged with human Alzheimer’s brain homogenate. Transcriptional changes are induced by Aβ including changes in genes involved in neurodegeneration and neuroinflammation. CT1812 treatment of these neurons caused changes in gene sets involved in synaptic function. These data support a role for transmembrane protein 97 in the synaptic binding of Aβ in human Alzheimer’s disease brain where it may mediate synaptotoxicity.
DOI: 10.6084/m9.figshare.24968769
title: Burnout and resilience in Sri Lankan HCWs Study

description: This study explores the relationship between burnout and mental health problems among health workers in Sri Lanka, and the role of resilience as a buffer. Data are based on self-report questionnaires including the Copenhagen Burnout Inventory, Brief Resilience Scale and Depression, anxiety and stress scale.
DOI: 10.25810/5dxz-xm93.68
title: Latin American Newspaper Coverage of Climate Change or Global Warming, 2005-2023 - November 2023

description: The Media and Climate Change Observatory Data monitors 126 sources (across newspapers, radio and TV) in 58 countries in seven different regions around the world. Data is assembled by accessing archives through the Lexis Nexis, Proquest and Factiva databases via the University of Colorado libraries. More information may be found at: http://mecco.colorado.edu.
DOI: 10.6084/m9.figshare.24968823
title: 20240110_starrydata2

description: All data on Starrydata2, a database of experimental properties in the field of inorganic materials
DOI: 10.6084/m9.figshare.24968823.v1
title: 20240110_starrydata2

description: All data on Starrydata2, a database of experimental properties in the field of inorganic materials
DOI: 10.5281/zenodo.10474631
title: Supplement to "Long-term stability, noise, and temperature sensitivity of modular porous-pot electrodes..."

description: Supplement to "Long-term stability, noise, and temperature sensitivity of modular porous-pot electrodes..."
DOI: 10.25810/fq7x-q521.48
title: Middle Eastern Newspaper Coverage of Climate Change or Global Warming, 2004-2023 - November 2023

description: The Media and Climate Change Observatory Data monitors 127 sources (across newspapers, radio and TV) in 59 countries in seven different regions around the world. Data is assembled by accessing archives through the Lexis Nexis, Proquest and Factiva databases via the University of Colorado libraries. More information may be found at: http://mecco.colorado.edu.
DOI: 10.14473/csda/cfl79i/fjywmh
title: K_CSDA00294.pdf

description: Karty
DOI: 10.14473/csda/cfl79i/34gone
title: PR03_CSDA00294.pdf

description: Tisková zpráva

Plýtvání potravinami, nákupní a spotřební chování českých domácností – Potraviny 2021
DOI: 10.14473/csda/cfl79i/fybthe
title: PR02_CSDA00294.pdf

description: Tisková zpráva

Způsob stravování, nakupování a chování české společnosti vzhledem k životnímu prostředí – Potraviny 2021
DOI: 10.14473/csda/cfl79i/6f6gv4
title: Potraviny_2021_FINALNI.tab

description: Data
DOI: 10.14473/csda/cfl79i/fkkfiy
title: PR04_CSDA00294.pdf

description: Tisková zpráva

Stravovací kultura Čechů a objednávání jídla přes rozvozové aplikace – Potraviny 2021
DOI: 10.14473/csda/cfl79i/w5jolf
title: TI_CSDA00294.pdf

description: Technická informace
DOI: 10.14473/csda/cfl79i/t1fhb4
title: OM_CSDA294.pdf

description: Ostatní materiály
DOI: 10.14473/csda/cfl79i/jialbk
title: PR05_CSDA00294.pdf

description: Tisková zpráva

Česká veřejnost o samozásobitelství a zahradničení – Potraviny 2021
DOI: 10.14473/csda/cfl79i/folf93
title: PR01_CSDA00294.pdf

description: Tisková zpráva

Česká veřejnost k problematice geneticky upravených plodin – Potraviny 2021
DOI: 10.14473/csda/cfl79i
title: Potraviny 2021

description: Výzkum Potraviny 2021provedl výzkumný tým CVVM Sociologického ústavu AV ČR, v.v.i.
DOI: 10.14473/csda/cfl79i/ghixsd
title: D_CSDA00294.pdf

description: Dotazník
DOI: 10.6084/m9.figshare.24906093
title: Integrative analysis of the metabolome and transcriptome provides insights into the mechanisms of Lignan biosynthesis in <i>Herpetospermum pedunculosum</i><i> </i>(Ser.) C. B. Clarke

description: Herpetospermum pedunculosum (Ser.) C. B. Clarke is a traditional Chinese herbal medicine that relies heavily on the lignans with antioxidant and hepatoprotective functions found in its dried ripe seeds (Herpetospermum caudigerum). However, little is known about the regulatory mechanisms of lignan biosynthesis in H. pedunculosum. Herein, we used metabolome (non-targeted UHPLC-MS/MS) to identify key metabolites, which are involved in the lignan production during green mature (GM) and yellow mature (YM) stages of the H. pedunculosum. Seeds of the Herpetospermum pedunculosum (Ser.) C. B. Clarke are green at the green mature stage (30 days after pollination, 30 DAP) and black at the yellow mature stage (60 days after pollination, 60 DAP).
DOI: 10.6084/m9.figshare.24906093.v1
title: Integrative analysis of the metabolome and transcriptome provides insights into the mechanisms of Lignan biosynthesis in <i>Herpetospermum pedunculosum</i><i> </i>(Ser.) C. B. Clarke

description: Herpetospermum pedunculosum (Ser.) C. B. Clarke is a traditional Chinese herbal medicine that relies heavily on the lignans with antioxidant and hepatoprotective functions found in its dried ripe seeds (Herpetospermum caudigerum). However, little is known about the regulatory mechanisms of lignan biosynthesis in H. pedunculosum. Herein, we used metabolome (non-targeted UHPLC-MS/MS) to identify key metabolites, which are involved in the lignan production during green mature (GM) and yellow mature (YM) stages of the H. pedunculosum. Seeds of the Herpetospermum pedunculosum (Ser.) C. B. Clarke are green at the green mature stage (30 days after pollination, 30 DAP) and black at the yellow mature stage (60 days after pollination, 60 DAP).
DOI: 10.6084/m9.figshare.24941373
title: ZNF263 PC-9OR CoIP-MS

description: CoIP-MS results in PC-9OR cells overexpressed with Flag-tagged ZNF263 to identify proteins interacting with ZNF263.
DOI: 10.6084/m9.figshare.24941373.v1
title: ZNF263 PC-9OR CoIP-MS

description: CoIP-MS results in PC-9OR cells overexpressed with Flag-tagged ZNF263 to identify proteins interacting with ZNF263.
DOI: 10.5281/zenodo.10475197
title: Dataset: Navigating complexity in inclusive pursuit: Proximal Policy Optimisation algorithm's role in Autonomous Decision-Making for Autism
DOI: 10.5281/zenodo.10475198
title: Dataset: Navigating complexity in inclusive pursuit: Proximal Policy Optimisation algorithm's role in Autonomous Decision-Making for Autism
DOI: 10.6084/m9.figshare.24941367
title: ZNF263 ChIP PC-9OR

description: ChIP sequencing data in PC-9OR cells overexrepssed with Flag-tagged ZNF263.
DOI: 10.6084/m9.figshare.24941367.v1
title: ZNF263 ChIP PC-9OR

description: ChIP sequencing data in PC-9OR cells overexrepssed with Flag-tagged ZNF263.
DOI: 10.14473/csda/rjs0yo/whej55
title: OM_CSDA00293.pdf

description: Ostatní materiály
DOI: 10.14473/csda/rjs0yo/n9shnf
title: Potraviny_FINALNI.tab

description: Data
DOI: 10.14473/csda/rjs0yo/kflosf
title: PR02_CSDA00293.pdf

description: Tisková zpráva

Vyhazování vzhledově nedokonalé zeleniny a ovoce jako jedna z forem plýtvání potravinami – Potraviny 2020
DOI: 10.14473/csda/rjs0yo/padhyf
title: PR03_CSDA00293.pdf

description: Tisková zpráva

Způsob stravování, nakupování a chování české společnosti vzhledem k životnímu prostředí – Potraviny 2020
DOI: 10.14473/csda/rjs0yo/ep67sp
title: PR04_CSDA00293.pdf

description: Tisková zpráva

Česká veřejnost o biopotravinách – Potraviny 2020
DOI: 10.14473/csda/rjs0yo/ikmspc
title: D_CSDA00293.pdf

description: Dotazník
DOI: 10.14473/csda/rjs0yo/eufked
title: K_CSDA00293.pdf

description: Karty
DOI: 10.6084/m9.figshare.24941349
title: LUAD clinical samples naive vs residual

description: Gene expression data (FPKM) with clincial tumor samples from advanced lung adenocarinoma patients treated with osimertinib before surgery compared to patients with no treatments.
DOI: 10.6084/m9.figshare.24941349.v1
title: LUAD clinical samples naive vs residual

description: Gene expression data (FPKM) with clincial tumor samples from advanced lung adenocarinoma patients treated with osimertinib before surgery compared to patients with no treatments.
DOI: 10.14473/csda/rjs0yo/njq47n
title: PR05_CSDA00293.pdf

description: Tisková zpráva

Česká veřejnost o lokálních potravinách – Potraviny 2020
DOI: 10.14473/csda/rjs0yo/u7gxxx
title: PR01_CSDA00293.pdf

description: Tisková zpráva

Plýtvání potravinami, nákupní a spotřební chování českých domácností – Potraviny 2020
DOI: 10.14473/csda/rjs0yo
title: Potraviny 2020

description: Výzkum Potraviny 2020 provedl výzkumný tým CVVM Sociologického ústavu AV ČR, v.v.i.
DOI: 10.6084/m9.figshare.24941319
title: LUAD parental vs osimertinib-resistant

description: Gene expression data (FPKM) of three lung adenocarcinoma cell lines (PC-9, HCC827, and H1975) with osimertinib-resistance compared to their parental cell lines.
DOI: 10.6084/m9.figshare.24941265
title: LUAD_NC vs ZNF263.xlsx

description: Gene expression data (FPKM) in three lung adenocarcinoma cell lines (PC-9, HCC827, and H1975) overexpressed with ZNF263 or vector.
DOI: 10.6084/m9.figshare.24941265.v1
title: LUAD_NC vs ZNF263.xlsx

description: Gene expression data (FPKM) in three lung adenocarcinoma cell lines (PC-9, HCC827, and H1975) overexpressed with ZNF263 or vector.
DOI: 10.14473/csda/wgcgsk/fr4rl4
title: D_CSDA00292.pdf

description: Dotaznik
DOI: 10.14473/csda/wgcgsk/k9pja9
title: TI_CSDA00292.pdf

description: Technická informace
DOI: 10.34740/kaggle/dsv/7370813
title: MoviesDatasets
DOI: 10.34740/kaggle/dsv/7370822
title: Mahanagar Yatayat Transport Dataset
DOI: 10.14473/csda/7ht1lh/8kzg3c
title: TI_CSDA00291.pdf

description: Technická informace
DOI: 10.14473/csda/7ht1lh/syeusm
title: Data_Hodnoty mladych_new.tab

description: Data
DOI: 10.14473/csda/7ht1lh/tq0cmn
title: D_CSDA00291.pdf

description: Dotazník
DOI: 10.14473/csda/vf8vfe/e7ckkg
title: TI_CSDA00288.pdf

description: Technická informace
DOI: 10.14473/csda/vf8vfe/tl8edb
title: D_CSDA00288.pdf

description: Dotazník
DOI: 10.14473/csda/vf8vfe
title: QUALITAS 2016

description: Data vznikla v rámci speciálního medicínsko-sociálního výzkum s názvem QUALITAS, na kterém spolupracují Sociologický ústav AV ČR, Fyziologický ústav AV ČR, IKEM a firma Synlab. Výzkum QUALITAS je zaměřený na zdraví a zdravý životní styl a jeho cílem je především studovat vliv životního stylu na různé aspekty rozvoje civilizačních chorob.
DOI: 10.14473/csda/vf8vfe/axmydo
title: DataQualitasArchive_FINALNI.tab

description: Data
DOI: 10.14473/csda/dpki0a/4gqdrl
title: data_pecovatele_new_opr.tab

description: Data
Podpora neformálních pečovatelů
DOI: 10.14473/csda/dpki0a/nanvan
title: TI_CSDA00167_a.pdf

description: Technická informace_a
Podpora neformálních pečovatelů
DOI: 10.14473/csda/dpki0a/9efbdg
title: OM_CSDA00167.pdf

description: Ostatní materiály
Podpora neformálních pečovatelů
DOI: 10.14473/csda/dpki0a/gaesej
title: D_CSDA00167.pdf

description: Dotazník
Podpora neformálních pečovatelů
DOI: 10.14473/csda/dpki0a
title: Podpora neformálních pečovatelů

description: Výzkum byl zaměřen na neformální pečovatele, jejichž péče je velmi intenzivní. Snažil se celkově zmapovat jejich životní situaci a problémy, kterým v souvislosti s péčí čelí. Zaměřen byl rovněž na jejich ekonomickou aktivitu, finanční situaci a další příbuzná témata. Výzkum není ze statistického pohledu reprezentativní, jsou v něm mimo jiné nadreprezentováni pečovatelé o OZP a menší kraje z důvodu možnosti jejich samostatné analýzy. Výzkum byl financován z prostředků Evropského sociálního fondu a Státního rozpočtu ČR a byl proveden agenturou STEM/MARK pro Fond dalšího vzdělávání v rámci projektu „podpora neformálních pečovatelů“ (CZ.1.04/3.1.00/C6.00002).
DOI: 10.14473/csda/dpki0a/kvxgt9
title: TI_CSDA00167.pdf

description: Technická informace
Podpora neformálních pečovatelů
DOI: 10.15139/s3/5pzd6r
title: ISHARE1 data set and code book

description: This is the data associated with ISHARE1.
DOI: 10.5281/zenodo.8236406
title: Negative emotions enhance memory-guided attention in a visual search task  by increasing frontoparietal, insular, and parahippocampal cortical activity

description: Previous literature has demonstrated that long-term memory representations guide the deployment of attentional resources during visual search in real-world pictures. However, it is currently unknown whether such a memory-guided visual search effect might be affected by the emotional context of the picture. Here, we addressed this question using functional magnetic resonance imaging (fMRI). Participants were asked to encode the position of a high-contrast target stimulus embedded in emotional (negative or positive) or neutral pictures. At retrieval, they performed a visual search for the target presented at the same location as encoding, but at a much lower contrast. Behavioral data showed that negative emotional pictures enhanced the effect of memory-guided attention, improving participants’ target detection performance. At the neural level, this effect was supported by increased activation in a large circuit of regions involving the dorsal and ventral frontoparietal cortex, insular and parahippocampal cortex. We propose that these regions might form an integrated neural circuit that is recruited to select and process previously encoded target locations (i.e., memory-guided attention sustained by the frontoparietal cortex) embedded in emotional contexts (i.e., emotional contexts recollection supported by the parahippocampal cortex and emotional monitoring supported by the insular cortex). Ultimately, these findings reveal that negative emotions can enhance memory-guided visual search performance by increasing neural activity in a large-scale brain circuit, contributing to disentangle the complex relationship between emotion, attention, and memory.
DOI: 10.5281/zenodo.8264425
title: Negative emotions enhance memory-guided attention in a visual search task  by increasing frontoparietal, insular, and parahippocampal cortical activity

description: Previous literature has demonstrated that long-term memory representations guide the deployment of attentional resources during visual search in real-world pictures. However, it is currently unknown whether such a memory-guided visual search effect might be affected by the emotional context of the picture. Here, we addressed this question using functional magnetic resonance imaging (fMRI). Participants were asked to encode the position of a high-contrast target stimulus embedded in emotional (negative or positive) or neutral pictures. At retrieval, they performed a visual search for the target presented at the same location as encoding, but at a much lower contrast. Behavioral data showed that negative emotional pictures enhanced the effect of memory-guided attention, improving participants’ target detection performance. At the neural level, this effect was supported by increased activation in a large circuit of regions involving the dorsal and ventral frontoparietal cortex, insular and parahippocampal cortex. We propose that these regions might form an integrated neural circuit that is recruited to select and process previously encoded target locations (i.e., memory-guided attention sustained by the frontoparietal cortex) embedded in emotional contexts (i.e., emotional contexts recollection supported by the parahippocampal cortex and emotional monitoring supported by the insular cortex). Ultimately, these findings reveal that negative emotions can enhance memory-guided visual search performance by increasing neural activity in a large-scale brain circuit, contributing to disentangle the complex relationship between emotion, attention, and memory.
DOI: 10.17638/datacat.liverpool.ac.uk/2573
title: Computational Data for Compositional Fields Explored with PhaseBO

description: Energies above the convex hull for Li-Sn-S-Cl, Y-Sr-Ti-O, and Li-Mg-P-Cl-Br phase fields, for which PhaseBO was performed to find the corresponding lowest energy compositions through the iterative PhaseBO exploration.
description: DFT computations data, calculated energies above convex hull
DOI: 10.25810/gyv-zg57.68
title: New Zealand Newspaper Coverage of Climate Change or Global Warming, 2000-2023 - November 2023

description: The Media and Climate Change Observatory Data monitors 127 sources (across newspapers, radio and TV) in 59 countries in seven different regions around the world. Data is assembled by accessing archives through the Lexis Nexis, Proquest and Factiva databases via the University of Colorado libraries. More information may be found at: http://mecco.colorado.edu.
DOI: 10.6073/pasta/0fb9c6eea290040edad3de1a7595f279
title: Epiphytic lichen surveys on 12 valleywide plots in Hubbard Brook 2016

description: Using the USFS FIA lichen indicator protocol we inventoried 12
 valleywide plots of mixed broadleaf and conifer tree composition over
 an elevation gradient to examine patterns of lichen abundance and
 diversity in the valley and their possible correspondence to air
 pollution indices and landscape variables. The surveys were conducted
 as part of an NSF funded LTER REU project by Aílis Clyne in 2016.
 Voucher specimens from this study were deposited at the Cornell Plant
 Pathology Herbarium (CUP) and the results published in the Journal of
 the Torrey Botanical Society.

 
 These data were gathered as part of the Hubbard Brook Ecosystem Study
 (HBES). The HBES is a collaborative effort at the Hubbard Brook
 Experimental Forest, which is operated and maintained by the USDA
 Forest Service, Northern Research Station.

 
 An analysis of these data can be found in: Natalie L. Cleavitt, Ailís
 B. Clyne, Timothy J. Fahey "Epiphytic macrolichen patterns along
 an elevation gradient in the White Mountain National Forest, New
 Hampshire," The Journal of the Torrey Botanical Society, 146(1),
 8-17, (21 January 2019)
DOI: 10.6073/pasta/63af7569519d3bb65058c7a5dc887922
title: Hubbard Brook Experimental Forest: Ice measurement study

description: A study was conducted at the Hubbard Brook Experimental Forest in New
 Hampshire, USA, to evaluate how measurements of ice accretion are
 affected by ice collector characteristics and configurations. Water
 was sprayed over passive ice collectors during freezing conditions to
 simulate ice storms of different intensity. The collectors consisted
 of plates composed of four different materials and installed
 horizontally; two different types of wires strung horizontally; and
 rods of three different materials, three different diameters, and
 installed at three different inclinations. Measurements were made with
 no ice and after approximately 0.25 and 0.50 inches of ice were
 applied. These data have been published in Campbell et al. 2020.

 
 Campbell, J. L., Rustad, L. E., Garlick, S., Newman, N., Stanovick, J.
 S., Halm, I., Driscoll, C. T., Barjenbruch, B. L., Burakowski, E.,
 Hilberg, S. D., Sanders, K. J., Shafer, J. C., & Doesken, N. J.
 (2020). A Comparison of Low-Cost Collector Configurations for
 Quantifying Ice Accretion, Journal of Applied Meteorology and
 Climatology, 59(9), 1429-1442.
 https://doi.org/10.1175/JAMC-D-19-0280.1
DOI: 10.6073/pasta/5e3b1193fb315be08940919619d44142
title: Beetle community at Hubbard Brook sampled by window traps 1973-1977 and 2015-2017

description: Beetles were sampled using window traps at in the same locations
 within the Hubbard Brook Experimental Forest, New Hampshire, in
 1973-1977 and again in 2015-2017. Samples were collected from late May
 through early August, but the number of weeks sampled differed among
 years. Most individuals collected were identified to the family level.
 For statistical analyses, counts by taxon for all samples were
 adjusted to a 48-hr collection period by simple linear interpolation.

 
 These data were gathered as part of the Hubbard Brook Ecosystem Study
 (HBES). The HBES is a collaborative effort at the Hubbard Brook
 Experimental Forest, which is operated and maintained by the USDA
 Forest Service, Northern Research Station.

 
 These data have been published in Harris, J.E., Rodenhouse, N.L. and
 Holmes, R.T., 2019. Decline in beetle abundance and diversity in an
 intact temperate forest linked to climate
 warming. Biological
 Conservation, 240, p.108219.
DOI: 10.6073/pasta/0091815dab851bf053528c878f963ec1
title: Sap Flow in the Soil Freezing Study at the Hubbard Brook Experimental Forest, 2010

description: The climate is changing in many temperate forests with the amount of
 forest area dominated by sugar maple experiencing an insulating
 snowpack expected to shrink between 49 and 95% compared to 1951-2005
 values. A reduced snowpack and increased depth and duration of soil
 frost can injure fine roots, which are essential for plant water
 uptake. Water uptake is a crucial component of ecosystem functioning
 because this process strongly impacts other biological processes, such
 as primary productivity and nutrient uptake. We evaluated the effects
 of changing winter climate, including snow and soil frost dynamics, by
 measuring sap flow rates in the Soil Freezing Study plots at the
 Hubbard Brook Experimental Forest.

 
 These data were gathered as part of the Hubbard Brook Ecosystem Study
 (HBES). The HBES is a collaborative effort at the Hubbard Brook
 Experimental Forest, which is operated and maintained by the USDA
 Forest Service, Northern Research Station.

 
 Analysis of these data are published in: Harrison, J.L., Reinmann,
 A.B., Maloney, A.S. et al. Transpiration of
 Dominant Tree Species Varies in Response to Projected Changes in
 Climate: Implications for Composition and Water Balance of Temperate
 Forest Ecosystems. Ecosystems (2020).
 https://doi.org/10.1007/s10021-020-00490-y