cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.3470375
title: JH Survey 2 20160701 EM3+ wav files

description: <br>Panshanger Barbastelle Survey 2<br>1 July 2016<br>21:25-23:00<br>Justin A T Halls<br>EM3+ 384ksps 16bit<br>Neumic microphone at 5%<br>Luton 9:50pm 12C 77% 1008hPa 6.7m/s WSW light cloud51.798956 -0.145018Pleasant, clear evening with base camp at the junction of two large and one smaller <br>ride through the coniferous part of the Panshanger woods. Quite breezy in open<br>areas at times. Mainly Common Pips with one or two Sopranos and a nyctalus,<br>probably Leislers. No confirmed Barbstelles at this location although we thought<br>we had a pair of Barbies fly past at 22:21, observed flying about waist height from the <br>northern ride and departing down the southern ride.<br>On analysis looks like BLE's, sweeping 50-25kHz with some second harmonic. Area<br>at the junction quite open so not likely to be Barbastelle clutter type calls.<br>The Tascam was located about a 100yards down the ride to the south and did not pick up<br>the 35kHz bat at all.<br>
DOI: 10.6084/m9.figshare.3470375.v1
title: JH Survey 2 20160701 EM3+ wav files

description: <br>Panshanger Barbastelle Survey 2<br>1 July 2016<br>21:25-23:00<br>Justin A T Halls<br>EM3+ 384ksps 16bit<br>Neumic microphone at 5%<br>Luton 9:50pm 12C 77% 1008hPa 6.7m/s WSW light cloud51.798956 -0.145018Pleasant, clear evening with base camp at the junction of two large and one smaller <br>ride through the coniferous part of the Panshanger woods. Quite breezy in open<br>areas at times. Mainly Common Pips with one or two Sopranos and a nyctalus,<br>probably Leislers. No confirmed Barbstelles at this location although we thought<br>we had a pair of Barbies fly past at 22:21, observed flying about waist height from the <br>northern ride and departing down the southern ride.<br>On analysis looks like BLE's, sweeping 50-25kHz with some second harmonic. Area<br>at the junction quite open so not likely to be Barbastelle clutter type calls.<br>The Tascam was located about a 100yards down the ride to the south and did not pick up<br>the 35kHz bat at all.<br>
DOI: 10.6084/m9.figshare.3470363
title: Pre- & Post-operative 3dMD Surface Scans

description: This folder contains the optical surface scans of the patients (with texture) in upright position, using the laser 3dMD system installed at the Royal Free Hospital.All image files can be opened up using the free-software Paraview (www.paraview.org).
DOI: 10.6084/m9.figshare.3470363.v2
title: Pre- & Post-operative 3dMD Surface Scans

description: This folder contains the optical surface scans of the patients (with texture) in upright position, using the laser 3dMD system installed at the Royal Free Hospital.All image files can be opened up using the free-software Paraview (www.paraview.org).
DOI: 10.6084/m9.figshare.3470363.v5
title: Pre- & Post-operative 3dMD Surface Scans

description: This folder contains the optical surface scans of the patients (with texture) in upright position, using the laser 3dMD system installed at the Royal Free Hospital.All image files can be opened up using the free-software Paraview (www.paraview.org).
DOI: 10.6084/m9.figshare.3470363.v4
title: Pre- & Post-operative 3dMD Surface Scans

description: This folder contains the optical surface scans of the patients (with texture) in upright position, using the laser 3dMD system installed at the Royal Free Hospital.All image files can be opened up using the free-software Paraview (www.paraview.org).
DOI: 10.6084/m9.figshare.3470336
title: High impact of sleeping problems on quality of life in transgender individuals: A cross-sectional multicenter study

description: Introduction Studies in the general population suggest that determinants of QoL are often sex-dependent. Sex-dependent analyses of QoL in transgender populations have not been performed so far. Methods In this cross-sectional multicentre study including 82 transwomen (TW) and 72 transmen (TM) at different treatment stages, we investigated potential determinants for QoL, assessed by the Short Form (36) Health Survey (SF-36), focusing on the impact of mood (BDI, STAI-X), sleep quality (PSQI), chronic pain (GPQ), body image (FBeK) and social support (SSS). Results The age-adjusted SF-36 total score and its subscales did not significantly differ between TM and TW. Using a multivariate regression analysis approach, we identified common but also sex-dependent determinants for QoL (Adjusted R<sup>2 </sup>= 0.228; 0.650 respectively). Accounting for general characteristics such as age, BMI and treatment status, sleep quality according to the PSQI was an independent and strong determinant of QoL in both sexes (β = -0.451, p =0.003 TM; β = -0.320; p = 0.0029 TW). Chronic pain was a significant independent predictor of QoL in TM (β = -0.298; p = 0.042) but not in TW. In contrast, anxiety (β= - 0.451; p&lt; 0.001) being unemployed (β= -0.206; p = 0.020) and insecurity about the own appearance (FBeK) (β= -0.261; p = 0.01) were independent predictors of QoL in TW. The rate of those reporting high sleep disturbances (PSQI ≥5) was high with 79.2% in TW and 81.2% in TM. Accordingly, age-adjusted QoL was also significantly lower in those reporting poor sleep in both sexes. Conclusions Sleep strongly affected QoL in both gender, while other factors, like pain and body image, seem to be gender specific in transgender individuals.
DOI: 10.6084/m9.figshare.3470336.v1
title: Raw_data.xlsx

description: Introduction Studies in the general population suggest that determinants of QoL are often sex-dependent. Sex-dependent analyses of QoL in transgender populations have not been performed so far. Methods In this cross-sectional multicentre study including 82 transwomen (TW) and 72 transmen (TM) at different treatment stages, we investigated potential determinants for QoL, assessed by the Short Form (36) Health Survey (SF-36), focusing on the impact of mood (BDI, STAI-X), sleep quality (PSQI), chronic pain (GPQ), body image (FBeK) and social support (SSS). Results The age-adjusted SF-36 total score and its subscales did not significantly differ between TM and TW. Using a multivariate regression analysis approach, we identified common but also sex-dependent determinants for QoL (Adjusted R<sup>2 </sup>= 0.228; 0.650 respectively). Accounting for general characteristics such as age, BMI and treatment status, sleep quality according to the PSQI was an independent and strong determinant of QoL in both sexes (β = -0.451, p =0.003 TM; β = -0.320; p = 0.0029 TW). Chronic pain was a significant independent predictor of QoL in TM (β = -0.298; p = 0.042) but not in TW. In contrast, anxiety (β= - 0.451; p&lt; 0.001) being unemployed (β= -0.206; p = 0.020) and insecurity about the own appearance (FBeK) (β= -0.261; p = 0.01) were independent predictors of QoL in TW. The rate of those reporting high sleep disturbances (PSQI ≥5) was high with 79.2% in TW and 81.2% in TM. Accordingly, age-adjusted QoL was also significantly lower in those reporting poor sleep in both sexes. Conclusions Sleep strongly affected QoL in both gender, while other factors, like pain and body image, seem to be gender specific in transgender individuals.
DOI: 10.6084/m9.figshare.3470321
title: Supplementary Material for: Is Intra-Arterial Treatment for Acute Ischemic Stroke Less Effective in Women than in Men?

description: <i>Introduction:</i> Stroke etiology and outcome after ischemic stroke differ between men and women. We examined if sex modifies the effect of intra-arterial treatment (IAT) in a randomized clinical trial of IAT for acute ischemic stroke in the Netherlands (MR CLEAN). <i>Patients and Methods:</i> The primary outcome was the score on the modified Rankin scale at 90 days. We tested for interaction between sex and treatment and estimated the treatment effect by sex with multiple ordinal logistic regression with adjustment for prognostic factors. <i>Results:</i> All 500 patients were included in the analysis; 292 (58.4%) were men. The treatment effect (adjusted common odds ratio) was 2.39 [95% confidence interval (CI) 1.55-3.68] in men and 0.99 (95% CI 0.60-1.66) in women (pinteraction = 0.016). In women, mortality was higher in the intervention group than in the control group (24 vs. 15%, p = 0.07). Serious adverse events occurred more often in women than in men undergoing intervention. There were no differences in neuro-imaging outcomes. <i>Discussion and Conclusion:</i> Contrary to other studies, we found a significant interaction between sex and treatment effect in the MR CLEAN trial. Pooled analyses of all published thrombectomy trials did not confirm this finding. In MR CLEAN, women seem to have a slightly more unfavorable profile, causing higher mortality and more serious adverse events, but insufficient to explain the absence of an overall effect. This suggests a play of chance and makes it clear that IAT should not be withheld in women.
DOI: 10.6084/m9.figshare.3470303
title: The taxonomic placement of the Miocene Patagonian frog <i>Wawelia gerholdi</i> (Amphibia: Anura)

description: Nicoli, L. Muzzopappa, P. & Faivovich, J., July 2016 The taxonomic placement of the Miocene frog <i>Wawelia gerholdi</i> (Amphibia: Anura). <i>Alcheringa 40</i>, xxx–xxx. ISSN 0311-5518. The Miocene frog <i>Wawelia gerholdi</i>, from northern Patagonia, was previously attributed to Ceratophryidae, the clade of extant South American horned frogs, making it one of the oldest records known for this group. However, the only known specimen has juvenile traits and is strongly similar to the australobatrachian <i>Calyptocephalella</i>. We re-examined the morphology of <i>W. gerholdi</i> and provide additional anatomical information and comparisons with juvenile individuals of Ceratophryidae and <i>Calyptocephalella gayi</i>, the only extant species of <i>Calyptocephalella</i>. We reject a close relationship between <i>W. gerholdi</i> and Ceratophryidae. Furthermore, the holotype is indistinguishable from juveniles of <i>C. gayi</i> and shares with all the species of this genus a character state combination that seems unique among anurans. Therefore, we consider <i>Wawelia</i> to be a junior synonym of <i>Calyptocephalella</i>. The problematic taxonomic status of numerous fossil species of <i>Calyptocephalella</i>, together with its untested monophyly, also prompts us to provisionally consider the extinct species as a <i>species inquirenda</i> included in this genus, pending a comprehensive revision of all available remains. <i>Laura Nicoli [</i>lnicoli@macn.gov.ar<i>] and Julián Faivovich [</i>julian@macn.gov.ar<i>], División Herpetología, and Paula Muzzopappa [</i>pmuzzopappa@macn.gov.ar<i>], Sección Paleontología de Vertebrados, Museo Argentino de Ciencias Naturales ‘Bernardino Rivadavia’-CONICET, Av. Angel Gallardo 470, C1405DJR, Buenos Aires, Argentina.</i>
DOI: 10.6084/m9.figshare.3470303.v1
title: The taxonomic placement of the Miocene Patagonian frog <i>Wawelia gerholdi</i> (Amphibia: Anura)

description: Nicoli, L. Muzzopappa, P. & Faivovich, J., July 2016 The taxonomic placement of the Miocene frog <i>Wawelia gerholdi</i> (Amphibia: Anura). <i>Alcheringa 40</i>, xxx–xxx. ISSN 0311-5518. The Miocene frog <i>Wawelia gerholdi</i>, from northern Patagonia, was previously attributed to Ceratophryidae, the clade of extant South American horned frogs, making it one of the oldest records known for this group. However, the only known specimen has juvenile traits and is strongly similar to the australobatrachian <i>Calyptocephalella</i>. We re-examined the morphology of <i>W. gerholdi</i> and provide additional anatomical information and comparisons with juvenile individuals of Ceratophryidae and <i>Calyptocephalella gayi</i>, the only extant species of <i>Calyptocephalella</i>. We reject a close relationship between <i>W. gerholdi</i> and Ceratophryidae. Furthermore, the holotype is indistinguishable from juveniles of <i>C. gayi</i> and shares with all the species of this genus a character state combination that seems unique among anurans. Therefore, we consider <i>Wawelia</i> to be a junior synonym of <i>Calyptocephalella</i>. The problematic taxonomic status of numerous fossil species of <i>Calyptocephalella</i>, together with its untested monophyly, also prompts us to provisionally consider the extinct species as a <i>species inquirenda</i> included in this genus, pending a comprehensive revision of all available remains. <i>Laura Nicoli [</i>lnicoli@macn.gov.ar<i>] and Julián Faivovich [</i>julian@macn.gov.ar<i>], División Herpetología, and Paula Muzzopappa [</i>pmuzzopappa@macn.gov.ar<i>], Sección Paleontología de Vertebrados, Museo Argentino de Ciencias Naturales ‘Bernardino Rivadavia’-CONICET, Av. Angel Gallardo 470, C1405DJR, Buenos Aires, Argentina.</i>
DOI: 10.6084/m9.figshare.3470294
title: Project VALKYRIE is active as of today

description: VALKYRIE (VALQUIRIA in portuguese) is a clinical trial studying the treatment of children and adolescents with diffuse tumors of the pons (brainstem), a serious disease difficult to treat, and currently with no established curative therapy. This study evaluates the possibility of improving treatment outcomes (quality of life and survival of patients) with the use of valproic acid, an antiepileptic drug already used for decades in children and adolescents. Recently, new discoveries have shown that most patients with diffuse pontine tumors have a genetic mutation which causes a change in the way the genes are rendered 'readable' by the cell machinery. This alteration can be reverted by valproic acid, and thus tumor cells may become less resistant to treatment.(excerpt).
DOI: 10.6084/m9.figshare.3470294.v1
title: VALKYRIE is active as of today

description: VALKYRIE (VALQUIRIA in portuguese) is a clinical trial studying the treatment of children and adolescents with diffuse tumors of the pons (brainstem), a serious disease difficult to treat, and currently with no established curative therapy. This study evaluates the possibility of improving treatment outcomes (quality of life and survival of patients) with the use of valproic acid, an antiepileptic drug already used for decades in children and adolescents. Recently, new discoveries have shown that most patients with diffuse pontine tumors have a genetic mutation which causes a change in the way the genes are rendered 'readable' by the cell machinery. This alteration can be reverted by valproic acid, and thus tumor cells may become less resistant to treatment.(excerpt).
DOI: 10.6084/m9.figshare.3470294.v3
title: Project VALKYRIE is active as of today

description: VALKYRIE (VALQUIRIA in portuguese) is a clinical trial studying the treatment of children and adolescents with diffuse tumors of the pons (brainstem), a serious disease difficult to treat, and currently with no established curative therapy. This study evaluates the possibility of improving treatment outcomes (quality of life and survival of patients) with the use of valproic acid, an antiepileptic drug already used for decades in children and adolescents. Recently, new discoveries have shown that most patients with diffuse pontine tumors have a genetic mutation which causes a change in the way the genes are rendered 'readable' by the cell machinery. This alteration can be reverted by valproic acid, and thus tumor cells may become less resistant to treatment.(excerpt).
DOI: 10.6084/m9.figshare.3470291
title: Hyperandrogenism deteriorates the quality of life in the Chinese women with polycystic ovary syndrome.xls

description: Polycystic ovary syndrome (PCOS) as a common metabolic and endocrine disorder among reproductive women in China, significantly affect the patients’ life qualities. Androgen has been known to contribute to the mood disturbance, little knows about the association between the high androgens level and the life quality in PCOS patients. Therefore, we wished to evaluate the correlation between the Chinese quality of life and androgens in PCOS. We recruited 80 PCOS patients and 40 healthy women from the Gynecology and Physical Examination Center. The quality of life was assessed by the Chinese quality of life instrument (ChQOL) questionnaire. The study protocol was approved by the Ethics Committee of the Heilongjiang University of Chinese Medicine. <br><br> <br>
DOI: 10.6084/m9.figshare.3470294.v2
title: VALKYRIE is active as of today

description: VALKYRIE (VALQUIRIA in portuguese) is a clinical trial studying the treatment of children and adolescents with diffuse tumors of the pons (brainstem), a serious disease difficult to treat, and currently with no established curative therapy. This study evaluates the possibility of improving treatment outcomes (quality of life and survival of patients) with the use of valproic acid, an antiepileptic drug already used for decades in children and adolescents. Recently, new discoveries have shown that most patients with diffuse pontine tumors have a genetic mutation which causes a change in the way the genes are rendered 'readable' by the cell machinery. This alteration can be reverted by valproic acid, and thus tumor cells may become less resistant to treatment.(excerpt).
DOI: 10.6084/m9.figshare.3470291.v1
title: PCOS.xls

description: Polycystic ovary syndrome (PCOS) as a common metabolic and endocrine disorder among reproductive women in China, significantly affect the patients’ life qualities. Androgen has been known to contribute to the mood disturbance, little knows about the association between the high androgens level and the life quality in PCOS patients. Therefore, we wished to evaluate the correlation between the Chinese quality of life and androgens in PCOS. We recruited 80 PCOS patients and 40 healthy women from the Gynecology and Physical Examination Center. The quality of life was assessed by the Chinese quality of life instrument (ChQOL) questionnaire. The study protocol was approved by the Ethics Committee of the Heilongjiang University of Chinese Medicine. <br><br> <br>
DOI: 10.6084/m9.figshare.3470291.v2
title: Hyperandrogenism deteriorates the quality of life in the Chinese women with polycystic ovary syndrome.xls

description: Polycystic ovary syndrome (PCOS) as a common metabolic and endocrine disorder among reproductive women in China, significantly affect the patients’ life qualities. Androgen has been known to contribute to the mood disturbance, little knows about the association between the high androgens level and the life quality in PCOS patients. Therefore, we wished to evaluate the correlation between the Chinese quality of life and androgens in PCOS. We recruited 80 PCOS patients and 40 healthy women from the Gynecology and Physical Examination Center. The quality of life was assessed by the Chinese quality of life instrument (ChQOL) questionnaire. The study protocol was approved by the Ethics Committee of the Heilongjiang University of Chinese Medicine. <br><br> <br>
DOI: 10.6084/m9.figshare.3470291.v3
title: Hyperandrogenism deteriorates the quality of life in the Chinese women with polycystic ovary syndrome.xls

description: Polycystic ovary syndrome (PCOS) as a common metabolic and endocrine disorder among reproductive women in China, significantly affect the patients’ life qualities. Androgen has been known to contribute to the mood disturbance, little knows about the association between the high androgens level and the life quality in PCOS patients. Therefore, we wished to evaluate the correlation between the Chinese quality of life and androgens in PCOS. We recruited 80 PCOS patients and 40 healthy women from the Gynecology and Physical Examination Center. The quality of life was assessed by the Chinese quality of life instrument (ChQOL) questionnaire. The study protocol was approved by the Ethics Committee of the Heilongjiang University of Chinese Medicine. <br><br> <br>
DOI: 10.6084/m9.figshare.3470291.v5
title: Hyperandrogenism deteriorates the quality of life in the Chinese women with polycystic ovary syndrome.xls

description: Polycystic ovary syndrome (PCOS) as a common metabolic and endocrine disorder among reproductive women in China, significantly affect the patients’ life qualities. Androgen has been known to contribute to the mood disturbance, little knows about the association between the high androgens level and the life quality in PCOS patients. Therefore, we wished to evaluate the correlation between the Chinese quality of life and androgens in PCOS. We recruited 80 PCOS patients and 40 healthy women from the Gynecology and Physical Examination Center. The quality of life was assessed by the Chinese quality of life instrument (ChQOL) questionnaire. The study protocol was approved by the Ethics Committee of the Heilongjiang University of Chinese Medicine. <br><br> <br>
DOI: 10.6084/m9.figshare.3470273.v4
title: Riedl et al Supporting Figure SF6 (figshare)

description: Western Blot of Caco-2 cells in 2D versus 3D<br>
DOI: 10.6084/m9.figshare.3470273.v5
title: Riedl et al Supporting Figures SF1-8 (figshare)

description: This dataset contains 8 Supporting Figures accompanying the article "Comparison of cancer cells cultured in 2D vs 3D reveals differences in AKT/mTOR/S6-kinase signaling and drug response" published in Journal of Cell Science
DOI: 10.6084/m9.figshare.3470210
title: Canopy removal experiment and recovery length

description: Data from two manipulative experiments investigating the effect of different level canopy removal on algal turf invasion in Capraia Island. <b>-RECOVERY LENGTH EXPERIMENT-</b>Datasets named <b>Rec.len_HSRturf_Capraia_2014 </b>and <b>Rec.len_HSRturf_Capraia_2015</b><b> </b>include data on propagation of algal turf for different level of canopy removal in 8 90x30 cm experimental transects. In each transect two region of different quality were produced: a cleared patch (30x30cm), where all erect organisms were removed and a canopy-degraded region (of 60x30cm) which was allocated to the following conditions: 0%, 25%, 50% and 75% of canopy removal. The cleared patch and canopy-degraded region were sampled at the scale of 2 x 2 cm, yielding 675 observations for each transect. Algal turfs cover was assessed twice: after one and two years from the set-up of the experiment (July 2014, July 2015).Datasets named <b>Rec.len_C.amentacea_2014</b> and <b>Rec.len_C.amentacea_2015</b> include data of <i>Cystoseira amentacea</i> cover of cleared patches in and canopy degraded region for each transect. <b>-CANOPY REMOVAL EXPERIMENT-</b>The dataset named <b>Exp.Can.rem_HSRTurf_2015</b> includes data of turf cover for different level of canopy removal (0%, 25%, 50% and 75%). 8 transects of 60 x 30 cm were randomly assigned that to these treatments:0%, 25%, 50% and 75% of canopy removed. Visual estimates of percentage cover of algal turfs was obtained by sampling these transects in July 2015 as described above. Dataset named <b>Exp</b><b>Canrem_</b><b>C.amentacea_2015 </b>include data of <i>Cystoseira amentacea</i> cover for each experimental transect.<b>-R SCRIPTS </b>The R file named <b>Maximum-Likelihood</b> estimation includes the script to conduct the maximum likelihood estimation of Turf-<i>Cystoseira </i>model parameter. The R file named <b>Rec_len_Bootstrap</b> includes the script to compute recovery length metrics (Half-point recovery length (<i>L<sub>half</sub></i>) and the Exponential recovery length (<i>L<sub>exp</sub>) )</i> and the bootstraps standard errors.