cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.14457/cu.the.2009.1555
title: Proposed guidelines for utilizing community learning resources in social studies instruction in secondary schools : a case study of Kampong Thom Province, Kingdom of Cambodia

description: To study the state and problems of utilizing community learning resources in social studies instruction of Cambodian teachers and to propose the guidelines for Cambodian secondary school teachers. The samples were 28 teachers teaching history, geography, and morals-civics from 7 High Schools in Kampong Thom Province, Kingdom of Cambodia. The data were collected through interview and were analyzed by content analysis, frequencies, and percentage. The findings revealed that explanation and additional homework were mostly utilized, the field trips were rarely organized, and written test was mostly used to assess studentsA learning outcomes. No schoolAs policy and no budget for supporting on organizing activities outside the class, a short amount of time for organizing activities outside the class, and teachersA lack of knowledge on methods for organizing activities outside the class and on community learning resources were the main problems. In the guidelines, the contents of social studies curriculum related to community learning resources, a list of community learning resources, methods for organizing activities, and samples of organizing activities for utilizing community learning resources in social studies instruction were presented. The guidelines that were verified by three Cambodian experts in the fields of social studies instruction and educational administration indicated that they were very appropriate and were considered as instructional innovation.
DOI: 10.14457/cu.the.2009.1556
title: Assessment tool of Thai menopause-specific quality of life in Surat Thani province, Thailand

description: Objective: To develop an assessment tool of Thai menopause-specific quality of life in Surat Thani Province, Thailand. Methodology: This study was divided research design into three phases as follows; phase 1 Concept clarification: a thorough study of related literature was conducted to search for the concept of menopause-specific quality of life and its existing instruments to guide developing instrument, phase II Item development: in-depth interviews with 30 Thai menopausal women in Surat Thani was conducted and an initial pool of items relating to menopause-specific quality of life was generated to develop the instrument, then, tested with 399 menopausal women, and phase III psychometric test: the developed questionnaire was tested for validity and reliability with 402 menopausal women. Result: The Thai Menopause-Specific Quality of Life instrument was well developed with 63 items, internal consistency reliability coefficient obtained 0.952, comprised of 3 domains including physic-psychological well-being (51 items), sexual-socio-economic well-being (9 items) and vasomotor well-being (3 items). Conclusion: The present study was directed to develop an effective instrument with integrity of psychometric property. This instrument was more likely meaningful to detect quality of life specific to Thai menopausal women.
DOI: 10.14457/cu.the.2009.1557
title: The relationships between affective variables, willingness to communicate in English, and English communication behaviors of Thai secondary school students

description: The present study aimed to investigate the levels of affective variables (international posture, English learning motivation, and confidence in English communication), WTC in English, and English communication behaviors of Thai secondary school students, the relationships between five constructs and the model of English communication in Thai contexts. The participants were 438 eleventh grade students in 11 public schools under Bangkok Educational Service Areas 1-3 in the academic year 2009. The research instruments were questionnaire, classroom observation scheme, and interview questions. The findings revealed that Thai secondary school students reported having English learning motivation at the high level and other four constructs at the moderate level. About the relationships between five constructs, WTC in English was found to have the relationship with English communication behaviors at the moderate level, and affective variables were found to have the relationships with WTC in English and English communication behaviors at the low level at the significant level of .05. The observation data showed that the students with higher WTC communicated more frequently than the ones with lower WTC. The interview data showed that students with high and low WTC had similar levels of affective variables. For the model of English communication in Thai contexts, the findings exhibited the different model from the theoretical model. The new model fitted in with the empirical data. The validation indicated the goodness of fit test: chi-square = 18.51, p = .95, df = 30, GFI = .99, AGFI = .97 and RMR = .033.
DOI: 10.14457/cu.the.2009.1559
title: Efficacy of standardized extract of centella asiatica ECa 233 in the management of minor aphthous ulceration

description: A randomized, single-blind, placebo controlled trial was conduted to evaluate the efficacy of an oral paste containing a standardized extract of centela asiatica on minor aphthous ulcer (MiRAU) in comparison to 10% triamcinolone (TA) oral paste. One hundred and twenty individuals, median age of 21 years, 37 males and 83 females, presented at least on MiRAU with an onset of no longer than 48 hours at entry (day 0) were recruitd by an announement to the public. They were randomy divided into 3 groups of treatment receiving placebo oral paste (control), 0.05% ECa 233 oral paste and 0.10% TA oral paste. Subjects were instructed to apply the medication by themselves 3 times a day for 10 days. In addition they were asked to make a daily recording of ulcer size, degree of pain and occurrence of new ulcer in a given daily booklet. Photograph was taken on day 0 and at the follow-up on day 3 and day 10. Initial mean ulcer size was 8.14 ± 0.75, 7.80 ± 0.66 and 8.74 ± 0.76 sq.mm and initial pain score assessed by a visual analog scale (VAS) was 6.53 ± 0.30, 6.63 ± 0,26 and 6.75 ± 0.29 in cotrol, 0.05% ECa 233 and 0.10% TA treated groups, respectively. Ulcer size in control group increased to its peak value on day 3 then gradually declined with mean time to complete healing of 8.65 ± 0.25 days. In contrast a prompt decrease was noted on day 1 and continued to decrease to reach a statistically significant difference from control on day 3 in both 0.05% ECa 233 or 0.10% TA treated group which accordingly exhibited complete healing in 6.63 ± 0.23 and 6.58 ± 0.25 days. Reduction of pain by 0.05% ECa 233 and 0.10% TA was clearly demonstrated on day 1 and pain score in both groups became significantly different from control group on day 3. In addition, no adverse effect was reported during the course of treatment of 11 days. Base on the results observed, 0.05% ECa 233 seems to be as effective as 0.10% TA in reducing the ulcer size as well as ulcer associated pain in MiRAU. Further study on the prevention of recurrence of MiRAU would strengthen the potential of ECa 233 as an effectve and safe alternative treatment of MiRAU.
DOI: 10.14457/cu.the.2009.1560
title: The impact of Korean television dramas on Thai society : a case study in Bangkok

description: To study the impact of Korean television dramas and the reason why Korean television dramas have influenced a Thai audience in Bangkok. The benefits from this research can be as a guideline for the government or the private sector to find out keys of success of Korean television dramas and use as a strategy to improve our dramas to attract the other counties that can bring an income to our country like a Korean wave phenomenon. The scope of this study is restricted on Thai society by using Thai audience in Bangkok who age between 18-60 years old that prefer to watch Korean television dramas, totaling 400 participants. The research used the methods of qualitative research which is collecting data from library books, related researches, journals, etc. and also the quantitative research to collect data by using a questionnaire as a tool. The data were analyzed by means of the Statistical Products and Service Solutions (SPSS) Program for the result. The research results are found that Korean television dramas have affected on Thai society on positive and negative. The impact on the positive of Korean television dramas mostly affected the audiences for relaxation and entertainment. Korean television dramas also have influenced them to travel to Korea including get knowledge of Korean culture. Besides, the impacts on negative of Korean television dramas were Thai people having excessive adapted to Korean culture, Thai culture have excessive dominated by Korean culture and Thai people were forgot Thai culture. Moreover, audiences have influenced to watch Korean television dramas by Korean wave. The Korean wave that mostly influences is tourist attraction, drama or movie and Korean music.
DOI: 10.14457/cu.the.2009.1561
title: Re-evaluating "Pro-Poor": a model for monitoring of the universal coverage scheme in Thailand

description: The Nation of Thailand, which had a GDP per capita of approximately $6,600 (PPP) at the time and was still struggling to recover from the crippling effects of the Asian Financial Crisis, was able to implement a universal coverage program for its citizens with a fairly comprehensive benefits package in 2001. However, the current system for universal health coverage in Thailand is a patchwork of 3 separate and unequal public health insurance schemes. Given the inequity in the Thai health system that preceded the Universal Coverage Scheme, monitoring of the program for pro-poor qualities is a critical aspect of ensuring that the Scheme meets its goal of providing universal access to high-quality healthcare for all. The primary objective of this research was to construct a conceptual model for pro-poor monitoring of the Universal Coverage Scheme based upon survey of frontline stakeholders, key informant interview, participant observation, review of health system data, and a theoretical framework based on development and sociological concepts rather than the more heavily emphasized quantitative health economic analytics. The results of the research appear to show that pro-poor monitoring indicators should be expanded beyond quantitative economic measures. Although the research did indicate that UC Scheme stakeholders are concerned about economic impacts and characteristics, it also revealed their strong concerns with heavy staff workloads, underfunding of services, and quality of care provided. While the health economic evaluations of the Scheme have accentuated the successful shift of the financial burden of care from the poor, they have been less revealing about the fact that much of that burden has fallen on public health facilities and their staff. In addition, there are no econometric indicators appropriate for determining the value of receiving high quality care when medically necessary. The results appear to indicate that additional metrics should be included in the monitoring model to help address these issues.
DOI: 10.14457/cu.the.2009.1562
title: Effect of RVV-X and RVV-X-specific antivenom on renal functions and coagulopathy in rats

description: Acute renal failure (ARF) is the most frequent and a serious complication in Russell’s viper bite victims. Russell's viper venom-factor X activator (RVV-X) has been identified as a main procoagulant enzyme involving coagulopathy, which might be responsible for changes in renal hemodynamics and functions. In this study, RVV-X was purified four fold from crude Russell's viper venom (cRVV) using a Sephadex G-100 gel filtration and then a Q-sepharose anion exchange column chromatography with approximately 5% yield. Purified RVV-X had coagulant and fibrinogenolytic functions. Then, we studied the effects of purified RVV-X and cRVV on DIC, renal hemodynamics and functions, as well as the accompanying histopathological changes in Sprague-Dawley rats (SD) (n = 6). The plasma D-dimer level was determined after intravenous injection of equipotent sublethal dose of cRVV (7 μg/kg) and purified RVV-X (1.75 μg/kg) in rats at various times. The plasma D-dimer levels increased and reached a peak at 10 min, declined temporarily and then reached another peak at 30 min after purified RVV-X injection, while plasma D-dimer levels of rats given cRVV gradually increased to reach a peak at 45 min. The higher plasma D-dimer level at 45 min of rats given crude venom is supposed to be due to the other coagulants in crude venom promoting coagulopathy. Changes in renal hemodynamic and function were evaluated using mean arterial pressure (MAP), glomerular filtration rate (GFR), effective renal plasma flow (ERPF), effective renal blood flow (ERBF), renal vascular resistance (RVR), and fractional excretion of all electrolytes (FE[subscript E]). After 10 min rat receiving both cRVV and purified RVV-X significantly decreased GFR, ERPF, ERBF and significantly increased RVR when compared to the normal saline control group. These changes correlated to the kidney lesions. There were no significant differences in renal hemodynamic and function parameters in rats injected with cRVV and purified RVV-X. These findings indicated that RVV-X plays an important role in renal hemodynamic and function changes through DIC. In addition, we established the rabbit anti-recombinant proteins IgG antibodies recognizing purified RVV-X but did not inhibit factor X activator activity of purified RVV-X. However, these rabbit anti-recombinant proteins IgG antibodies cross reacted with Cryptelytrops albolabris and Calloselasma rhodostoma venoms. Further studies are needed to use these antibodies to further develop the affinity column for purification of snake molecules for drug discovery.
DOI: 10.14457/cu.the.2009.1563
title: Romantische elemente in Michael Endes phantastischen kinder-und jugendromanen

description: In der vorliegenden Magisterarbeit werden die romantischen Elemente in drei phantastischen Kinder- und Jugendromanen von Michael Ende untersucht, nämlich Jim Knopf und Lukas der Lokomotivführer, Momo und Die unendliche Geschichte. In der Arbeit wird untersucht, wie Michael Ende die romantischen Elemente in seinen Romanen darstellt. Die Gemeinsamkeiten und Unterschiede der romantischen Elemente in seinen einzelnen Romanen werden ebenfalls analysiert. Aus der Untersuchung geht hervor, dass Michael Ende ein moderner Autor ist, der von der Romantik beeinflusst wird. In seinen drei ausgewählten Romanen kommen verschiedene romantischen Elemente vor, nämlich Erscheinungsformen, Schreibtechnik und Themen. Außerdem erscheinen in diesen drei Romanen die romantischen Motive, Symbole und Allegorien, die den großen Vorbildern der Romantiker nachstreben, nämlich Novalis und E.T.A. Hoffmann. Allerdings werden die romantischen Elemente sowohl ähnlich als auch unterschiedlich dargestellt, denn sie werden in verschiedenen Zeitperioden geschrieben. Die gesellschaftlichen Hintergründe und Einstellungen in den einzelnen Zeitperioden üben deshalb einen Einfluss auf seine Werke aus. Aus den Untersuchungsergebnissen können wir aber schließen, dass Michael Ende die romantischen Gedanken und Motive als Grundlage für seine drei phantastischen Kinderund Jugendromane verwendet.
DOI: 10.14457/cu.the.2009.1564
title: Basophil activation test in diagnosis of immediate iodinated contrast media hypersensitivity patients

description: The diagnosis and prevention of iodinated contrast media or radiocontrast media (RCM) hypersensitivity is still a major problem in clinical practice. At present, there are no alternative methods to diagnose RCM-induced hypersensitivity reaction other than history taking. Basophil activation test (BAT) by determining CD63 expression on basophil cell surface was demonstrated to correlate with hypersensitivity drug reactions. The purpose of this study, therefore, aims to explore the possibility whether BAT play a role in the diagnosis of patients with a history of RCM-induced immediate hypersensitivity reaction. Whole blood from 24 patients and 14 healthy donors were incubated in the presence or absence of 1:10 and 1:100 dilution concentrations of radiocontrast media. Levels of CD63 expressions on basophil surface were consequently determined by fluorescence staining and Flow cytometry analysis. The result from the study indicated that basophils from 13 out of 24 patients with a history of RCM reactions (54.17%) had increased CD63 expression and 11 out of 13 patients showed positive BAT result to both 1:10 and 1:100 concentrations of incubated RCM. Sensitivity and specificity of BAT were 54.17% and 92.86%, respectively. BAT results were not significantly different between skin test positive and skin test negative patients. In addition, BAT in combination with skin test results had increased sensitivity to 70.8%. In conclusion, basophil activation test (BAT) may be potentially useful in the diagnosis of patients with RCM-induced hypersensitivity reactions.
DOI: 10.14457/cu.the.2009.1565
title: Effects of genistein and exercise training on endothelial dysfunction in aging male rats

description: The present study aims to investigate the effects of genistein, a potent phyto-antioxidant, and exercise training on age-induced endothelial dysfunction. Male Wistar rats (20-22-month old) were divided into five groups: 1) aged rats treated with corn oil (Aged+Veh), 2) aged rats treated with genistein (Aged+Gen, (0.25 mg/kg BW/day, s.c.)), 3) aged rats without exercise training (Aged+Without-Ex), 4) aged rats with exercise training (Aged+Ex, swimming 40 min/day, 5 days/week for 8 weeks), and 5) aged rats treated with both genistein and exercise training (Aged+Gen+Ex) group. The cremaster arterioles response to acetylcholine (Ach; 10⁻⁵ M, 5ml/5min) was accessed after 1-min norepinephrine preconstriction (10 μM). To determine NO bioavailability, the Krebs-Ringer buffer with 4, 5-diaminofluorescein-diacetate (3 μM DAF-2DA), and 10 μM Ach saturated with 95%N2 and 5%CO₂ were used. Changes NO-associated fluorescent intensity along the cremaster arterioles were analyzed by the Image Pro-Plus Software. Liver malondialdehyde (MDA) level was measured by thiobarbituric acid reaction and used as an indicator for oxidative stress. TNF-α level was determined by ELISA kit. The results showed that the mean arterial blood pressure (MAP), MDA level and TNF-α level of Aged groups (Aged+Without-Ex and Aged+Veh) were significantly increased when compared to controls. MAP, MDA level and TNF-α level of Aged-treated group (Aged+Gen, Aged+Ex and Aged+Gen+Ex groups) were significantly decreased as compared to their age-matched control groups (P&lt;0.05). In these three groups of treatments, Ach-induced vasodilation after preconstriction with norepinephrine and NO-associated fluorescent intensity were significantly increased as compared to their age-matched control groups (P&lt;0.05). The correlation between, Ach-induced vasodilatation and NO-associated fluorescent intensity was demonstrated and represented by a linear line: y = 0.4276x – 2.0966, R²=0.82, (P&lt;0.01). These findings indicated that genistein and exercise training could improve age-induced endothelial dysfunction via reduced oxidative stress, reduced TNF-α and increased NO bioavailability.
DOI: 10.14457/cu.the.2009.1566
title: Use of phage display technology to identify proteins that interact with LipL32, the major outer membrane protein of pathogenic Leptospira

description: Leptospirosis is one of the most common zoonotic diseases worldwide. The causative agent of leptospirosis is pathogenic spirochetal bacteria named Leptospira interrogans. Leptospirosis presents broad spectrum of clinical features. However, pathogenesis remains unclear. The initial step of infection requires host-pathogen interaction. Outer membrane components including outer membrane proteins (OMPs) may play a key role in host-microbe interactions. LipL32 is the major OMP that is conserved among pathogenic leptospires, constitutively expressed, immunogenic, and capable of binding to extracellular matrix of mammalian cell. To identify the host proteins that interact with LipL32, phage display technology was employed in our study. Recombinant LipL32 was produced and used as a target molecule for biopanning with random heptapeptide phage library (Ph.D.-7). Then, 52 randomly selected plaques from the third round of panning were sequenced. The result showed 6 peptide sequence patterns. The most frequent peptide sequence is WHWTYYW. From database search, putative proteins that potentially bind to LipL32 include scavenger receptor class F, chloride channel assembly 2, laminin α-5, coronin 2A, proataglandin E receptor 1 and glycoprotein VI. However, the interactions of LipL32 with these host proteins and their roles in the pathogenesis of leptospirosis require further investigation.
DOI: 10.14457/cu.the.2009.1567
title: Effect of extracts from green vegetables on modification of mutagenicity of nitrite-treated aminopyrene and nitrite-treated chicken extract using ames test

description: The extracts from leaves of raw and blanched vegetables, namely Cha-Plu (Piper sarmentosum Roxb.), Yor (Morinda citrifolia L.), Pak-Waan-Bann (Sauropus androgynus Merr.), and Pak-Khom (Amaranthus lividus Linn.) did not have mutagenicity when they were tested by using Salmonella typhimurium strain TA98 and TA100 of the Ames test. However, they were mutagenic after reacted with nitrite in an acidic condition (pH3-3.5) without activating system on both strains. The standard mutagen models were 1-aminopyrene treated with nitrite and chicken extract treated with nitrite. The results revealed that the extracts from raw and blanched vegetables could reduce the direct-acting mutagenicity of compounds that occurred in the two models on both tester strains. The antimutagenicity of each extract added to the first model was strong (&gt;60% inhibition) while it was moderate to weak in the second model, except the extract from raw Pak-Khom showed no active on both strains in second model. The results showed that the potency of antimutagenicity was not dose-dependent. Antimutagenicity of compounds in vegetable extracts might counteract the direct-acting mutagenicity of nitrite treated 1-aminopyrene and nitrite treated chicken extract. The results indicated that antimutagenic effect of extracts from blanched vegetables was not reduced compared with raw vegetables. It was concluded that heat processing had not an effect on antimutagenic activity of each vegetable. This experiment suggested that consumption of nitrite-containing foods with these vegetables (raw and blanched) should prevent the mutagenicity of direct mutagen occurring in gastric like condition.