cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.15468/dl.6yewpc
title: Occurrence Download

description: A dataset containing 22137 species occurrences available in GBIF matching the query:
{
 "and" : [
 "DatasetKey is Global compendium of Aedes albopictus occurrence",
 "TaxonKey is Aedes albopictus (Skuse, 1894)"
 ]
}

 The dataset includes 22137 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0075738-240626123714530/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.7tfy92
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "Geometry" : [
 "MULTIPOLYGON (((144.773978 -36.975367, 144.773978 -36.977612, 144.778469 -36.977612, 144.778469 -36.975367, 144.773978 -36.975367)), ((144.778469 -36.977612, 144.778469 -36.982104, 144.773978 -36.982104, 144.773978 -36.98435, 144.780715 -36.98435, 144.780715 -36.977612, 144.778469 -36.977612)), ((144.780715 -36.98435, 144.780715 -36.988841, 144.785207 -36.988841, 144.785207 -36.98435, 144.780715 -36.98435)))"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0075739-240626123714530/datasets/export for details.
DOI: 10.6084/m9.figshare.26784610
title: <b>Yinqin Qingfei granules alleviate </b><b><i>Mycoplasma pneumoniae </i></b><b>pneumonia </b><b><i>via </i></b><b>inhibiting NLRP3 inflammasome-mediated macrophage pyroptosis</b>

description: <b>Background:</b> <i>Mycoplasma pneumoniae</i> pneumonia (MPP) is a prevalent respiratory infectious disease in children. Given the increasing resistance of <i>Mycoplasma pneumoniae</i> (MP) to macrolide antibiotics, the identification of new therapeutic agents is critical. Yinqin Qingfei granules (YQQFG), a Chinese patent medicine formulated specifically for pediatric MPP, lacks a clear explanation of its mechanism.<b>Methods:</b> The primary components of YQQFG were identified using LC-MS/MS. <i>In </i><i>vitro</i>, RAW264.7 cells infected with MP underwent morphological examination via scanning electron microscopy. Drug-containing serum was prepared, and its intervention concentration was determined using the CCK-8 assay. The active components of YQQFG were molecularly docked with NLRP3 protein using Autodock Vina software. A RAW264.7 cell line overexpressing NLRP3 was created using lentivirus to pinpoint the target of YQQFG. <i>In </i><i>vivo</i>, MPP model mice were established via nasal instillation of MP. Lung damage was assessed by lung index and H&E staining. Pyroptosis-associated protein levels in cells and lung tissue were measured by western blot, while interleukin (IL)-1β and IL-18 levels in cell supernatants and mouse serum were quantified using ELISA. Immunofluorescence double staining of lung tissue sections was conducted to assess the correlation between NLRP3 protein expression and macrophages. The expression of the community-acquired respiratory distress syndrome toxin (CARDS TX) was evaluated by qPCR.<b>Results:</b> 25 effective components with favorable oral bioavailability were identified in YQQFG. Both in vitro and in vivo studies demonstrated that YQQFG substantially reduced the expression of the NLRP3/Caspase-1/GSDMD pathway, decreasing the release of IL-1β and IL-18, and inhibited MP exotoxin. Molecular docking indicated strong affinity between most YQQFG components and NLRP3 protein. Lentivirus transfection and immunofluorescence double staining confirmed that YQQFG significantly suppressed NLRP3 expression in macrophages, outperforming azithromycin(AZM). The combination of YQQFG and AZM yielded the optimal therapeutic effect for MPP.<b>Conclusion:</b> YQQFG mitigates inflammatory responses by suppressing NLRP3 inflammasome-mediated macrophage pyroptosis, thereby ameliorating MP-induced acute lung injury. YQQFG serves as an effective adjunct and alternative medication for pediatric MPP treatment.
DOI: 10.6084/m9.figshare.26784610.v1
title: Yinqin Qingfei granules alleviate <i>Mycoplasma pneumoniae</i> pneumonia <i>via</i> inhibiting NLRP3 inflammasome-mediated macrophage pyroptosis

description: <b>Background:</b> <i>Mycoplasma pneumoniae</i> pneumonia (MPP) is a prevalent respiratory infectious disease in children. Given the increasing resistance of <i>Mycoplasma pneumoniae</i> (MP) to macrolide antibiotics, the identification of new therapeutic agents is critical. Yinqin Qingfei granules (YQQFG), a Chinese patent medicine formulated specifically for pediatric MPP, lacks a clear explanation of its mechanism.<b>Methods:</b> The primary components of YQQFG were identified using LC-MS/MS. In vitro, RAW264.7 cells infected with MP underwent morphological examination via scanning electron microscopy. Drug-containing serum was prepared, and its intervention concentration was determined using the CCK-8 assay. The active components of YQQFG were molecularly docked with NLRP3 protein using Autodock Vina software. A RAW264.7 cell line overexpressing NLRP3 was created using lentivirus to pinpoint the target of YQQFG. In vivo, MPP model mice were established via nasal instillation of MP. Lung damage was assessed by lung index and H&E staining. Pyroptosis-associated protein levels in cells and lung tissue were measured by western blot, while interleukin (IL)-1β and IL-18 levels in cell supernatants and mouse serum were quantified using ELISA. Immunofluorescence double staining of lung tissue sections was conducted to assess the correlation between NLRP3 protein expression and macrophages. The expression of the community-acquired respiratory distress syndrome toxin (CARDS TX) was evaluated by qPCR.<b>Results:</b> 25 effective components with favorable oral bioavailability were identified in YQQFG. Both in vitro and in vivo studies demonstrated that YQQFG substantially reduced the expression of the NLRP3/Caspase-1/GSDMD pathway, decreasing the release of IL-1β and IL-18, and inhibited MP exotoxin. Molecular docking indicated strong affinity between most YQQFG components and NLRP3 protein. Lentivirus transfection and immunofluorescence double staining confirmed that YQQFG significantly suppressed NLRP3 expression in macrophages, outperforming azithromycin(AZM). The combination of YQQFG and AZM yielded the optimal therapeutic effect for MPP.<b>Conclusion:</b> YQQFG mitigates inflammatory responses by suppressing NLRP3 inflammasome-mediated macrophage pyroptosis, thereby ameliorating MP-induced acute lung injury. YQQFG serves as an effective adjunct and alternative medication for pediatric MPP treatment.
DOI: 10.6084/m9.figshare.26784610.v2
title: <b>Yinqin Qingfei granules alleviate </b><b><i>Mycoplasma pneumoniae </i></b><b>pneumonia </b><b><i>via </i></b><b>inhibiting NLRP3 inflammasome-mediated macrophage pyroptosis</b>

description: <b>Background:</b> <i>Mycoplasma pneumoniae</i> pneumonia (MPP) is a prevalent respiratory infectious disease in children. Given the increasing resistance of <i>Mycoplasma pneumoniae</i> (MP) to macrolide antibiotics, the identification of new therapeutic agents is critical. Yinqin Qingfei granules (YQQFG), a Chinese patent medicine formulated specifically for pediatric MPP, lacks a clear explanation of its mechanism.<b>Methods:</b> The primary components of YQQFG were identified using LC-MS/MS. <i>In </i><i>vitro</i>, RAW264.7 cells infected with MP underwent morphological examination via scanning electron microscopy. Drug-containing serum was prepared, and its intervention concentration was determined using the CCK-8 assay. The active components of YQQFG were molecularly docked with NLRP3 protein using Autodock Vina software. A RAW264.7 cell line overexpressing NLRP3 was created using lentivirus to pinpoint the target of YQQFG. <i>In </i><i>vivo</i>, MPP model mice were established via nasal instillation of MP. Lung damage was assessed by lung index and H&E staining. Pyroptosis-associated protein levels in cells and lung tissue were measured by western blot, while interleukin (IL)-1β and IL-18 levels in cell supernatants and mouse serum were quantified using ELISA. Immunofluorescence double staining of lung tissue sections was conducted to assess the correlation between NLRP3 protein expression and macrophages. The expression of the community-acquired respiratory distress syndrome toxin (CARDS TX) was evaluated by qPCR.<b>Results:</b> 25 effective components with favorable oral bioavailability were identified in YQQFG. Both in vitro and in vivo studies demonstrated that YQQFG substantially reduced the expression of the NLRP3/Caspase-1/GSDMD pathway, decreasing the release of IL-1β and IL-18, and inhibited MP exotoxin. Molecular docking indicated strong affinity between most YQQFG components and NLRP3 protein. Lentivirus transfection and immunofluorescence double staining confirmed that YQQFG significantly suppressed NLRP3 expression in macrophages, outperforming azithromycin(AZM). The combination of YQQFG and AZM yielded the optimal therapeutic effect for MPP.<b>Conclusion:</b> YQQFG mitigates inflammatory responses by suppressing NLRP3 inflammasome-mediated macrophage pyroptosis, thereby ameliorating MP-induced acute lung injury. YQQFG serves as an effective adjunct and alternative medication for pediatric MPP treatment.
DOI: 10.15468/dl.fz9yzf
title: Occurrence Download

description: A dataset containing 1714213 species occurrences available in GBIF matching the query:
{
 "DatasetKey" : [
 "is Pl@ntNet observations"
 ]
}

 The dataset includes 1714213 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0075693-240626123714530/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.bfqb4x
title: Occurrence Download

description: A dataset containing 69686 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Continent is Asia",
 "Country is one of (Brunei Darussalam, Cambodia, Indonesia, Lao People’s Democratic Republic, Malaysia, Myanmar, Philippines, Singapore, Thailand, Viet Nam)",
 "IucnRedListCategory is one of (EX, EW, CR, EN, VU, NT, LC, DD, NE)",
 "OccurrenceStatus is Present",
 "TaxonKey is Ascomycota"
 ]
}

 The dataset includes 69686 records from 194 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0075723-240626123714530/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.13347809
title: Material da Revisão Sistemática do Paper Ensino de Algoritmos e Programação na Educação Profissional Técnica: Uma Revisão Sistemática da Literatura
DOI: 10.5281/zenodo.13347810
title: Material da Revisão Sistemática do Paper Ensino de Algoritmos e Programação na Educação Profissional Técnica: Uma Revisão Sistemática da Literatura
DOI: 10.5281/zenodo.13347736
title: RAW DATA - Control of Intermolecular Interactions toward the Production of Free-Standing Interfacial Polydopamine Films - ACS Applied Materials & Interfaces 2023 15 (30), 36922-36935 DOI: 10.1021/acsami.3c05236

description: This repository contains RAW data for the experiment described in the publication:

 

Jakub Szewczyk, Visnja Babacic, Adam Krysztofik, Olena Ivashchenko, Mikołaj Pochylski, Robert Pietrzak, Jacek Gapiński, Bartłomiej Graczykowski, Mikhael Bechelany, and Emerson Coy, Control of Intermolecular Interactions toward the Production of Free-Standing Interfacial Polydopamine Films, ACS Applied Materials & Interfaces 2023 15 (30), 36922-36935, DOI: 10.1021/acsami.3c05236.

 

For more information please contact the corresponding authors.
DOI: 10.5281/zenodo.13347737
title: RAW DATA - Control of Intermolecular Interactions toward the Production of Free-Standing Interfacial Polydopamine Films - ACS Applied Materials & Interfaces 2023 15 (30), 36922-36935 DOI: 10.1021/acsami.3c05236

description: This repository contains RAW data for the experiment described in the publication:

 

Jakub Szewczyk, Visnja Babacic, Adam Krysztofik, Olena Ivashchenko, Mikołaj Pochylski, Robert Pietrzak, Jacek Gapiński, Bartłomiej Graczykowski, Mikhael Bechelany, and Emerson Coy, Control of Intermolecular Interactions toward the Production of Free-Standing Interfacial Polydopamine Films, ACS Applied Materials & Interfaces 2023 15 (30), 36922-36935, DOI: 10.1021/acsami.3c05236.

 

For more information please contact the corresponding authors.
DOI: 10.5281/zenodo.10804349
title: Deflections of the s-FKLP model for validation purposes
title: Ugięcia modelu s-FKLP na potrzeby walidacji

description: The test data included are for plate deflections obtained according to the s-FKLP model produced for model validation. The methodology and analysis of the obtained data is included in the Open Access article:

Stempin, P.; Pawlak, T. P. & Sumelka, W.Formulation of non-local space-fractional plate model and validation for composite micro-plates International Journal of Engineering Science, Elsevier BV, 2023, 192, 103932.

DOI: https://doi.org/10.1016/j.ijengsci.2023.103932

 
description: Zamieszczone dane badawcze dotyczą ugięć płyty otrzymanych wg modelu s-FKLP wytworzonych na potrzebę walidacji modelu. Metodologia i analiza otrzymanych danych zawarta jest w artykule Open Access: 

Stempin, P.; Pawlak, T. P. & Sumelka, W.Formulation of non-local space-fractional plate model and validation for composite micro-plates International Journal of Engineering Science, Elsevier BV, 2023, 192, 103932.

DOI: https://doi.org/10.1016/j.ijengsci.2023.103932
DOI: 10.5281/zenodo.10804350
title: Deflections of the s-FKLP model for validation purposes
title: Ugięcia modelu s-FKLP na potrzeby walidacji

description: The test data included are for plate deflections obtained according to the s-FKLP model produced for model validation. The methodology and analysis of the obtained data is included in the Open Access article:

Stempin, P.; Pawlak, T. P. & Sumelka, W.Formulation of non-local space-fractional plate model and validation for composite micro-plates International Journal of Engineering Science, Elsevier BV, 2023, 192, 103932.

DOI: https://doi.org/10.1016/j.ijengsci.2023.103932

 
description: Zamieszczone dane badawcze dotyczą ugięć płyty otrzymanych wg modelu s-FKLP wytworzonych na potrzebę walidacji modelu. Metodologia i analiza otrzymanych danych zawarta jest w artykule Open Access: 

Stempin, P.; Pawlak, T. P. & Sumelka, W.Formulation of non-local space-fractional plate model and validation for composite micro-plates International Journal of Engineering Science, Elsevier BV, 2023, 192, 103932.

DOI: https://doi.org/10.1016/j.ijengsci.2023.103932
DOI: 10.5281/zenodo.10804525
title: Deflections of the s-FKLP model for parametric study purposes
title: Ugięcia modelu s-FKLP na potrzeby studium parametrycznego

description: The test data included are for plate deflections obtained according to the s-FKLP model produced for parametric study purposes. The methodology and analysis of the obtained data is included in the Open Access article:

Stempin, P.; Pawlak, T. P. & Sumelka, W.Formulation of non-local space-fractional plate model and validation for composite micro-platesInternational Journal of Engineering Science, Elsevier BV, 2023, 192, 103932.

DOI: https://doi.org/10.1016/j.ijengsci.2023.103932
description: Zamieszczone dane badawcze dotyczą ugięć płyty otrzymanych wg modelu s-FKLP wytworzonych na potrzebę studium parametrycznego. Metodologia i analiza otrzymanych danych zawarta jest w artykule Open Access: 

Stempin, P.; Pawlak, T. P. & Sumelka, W.Formulation of non-local space-fractional plate model and validation for composite micro-platesInternational Journal of Engineering Science, Elsevier BV, 2023, 192, 103932.

DOI: https://doi.org/10.1016/j.ijengsci.2023.103932
DOI: 10.5281/zenodo.10804526
title: Deflections of the s-FKLP model for parametric study purposes
title: Ugięcia modelu s-FKLP na potrzeby studium parametrycznego

description: The test data included are for plate deflections obtained according to the s-FKLP model produced for parametric study purposes. The methodology and analysis of the obtained data is included in the Open Access article:

Stempin, P.; Pawlak, T. P. & Sumelka, W.Formulation of non-local space-fractional plate model and validation for composite micro-platesInternational Journal of Engineering Science, Elsevier BV, 2023, 192, 103932.

DOI: https://doi.org/10.1016/j.ijengsci.2023.103932
description: Zamieszczone dane badawcze dotyczą ugięć płyty otrzymanych wg modelu s-FKLP wytworzonych na potrzebę studium parametrycznego. Metodologia i analiza otrzymanych danych zawarta jest w artykule Open Access: 

Stempin, P.; Pawlak, T. P. & Sumelka, W.Formulation of non-local space-fractional plate model and validation for composite micro-platesInternational Journal of Engineering Science, Elsevier BV, 2023, 192, 103932.

DOI: https://doi.org/10.1016/j.ijengsci.2023.103932
DOI: 10.5281/zenodo.10805044
title: Deflections of the s-FKLP model for parametric study purposes
title: Ugięcia modelu s-FKLP na potrzeby studium parametrycznego

description: The test data included are for plate deflections obtained according to the s-FKLP model produced for parametric study purposes. The methodology and analysis of the obtained data is included in the Open Access article:

Stempin, P.; Pawlak, T. P. & Sumelka, W.Formulation of non-local space-fractional plate model and validation for composite micro-platesInternational Journal of Engineering Science, Elsevier BV, 2023, 192, 103932.

DOI: https://doi.org/10.1016/j.ijengsci.2023.103932
description: Zamieszczone dane badawcze dotyczą ugięć płyty otrzymanych wg modelu s-FKLP wytworzonych na potrzebę studium parametrycznego. Metodologia i analiza otrzymanych danych zawarta jest w artykule Open Access: 

Stempin, P.; Pawlak, T. P. & Sumelka, W.Formulation of non-local space-fractional plate model and validation for composite micro-platesInternational Journal of Engineering Science, Elsevier BV, 2023, 192, 103932.

DOI: https://doi.org/10.1016/j.ijengsci.2023.103932
DOI: 10.15468/dl.sqcft7
title: Occurrence Download

description: A dataset containing 1 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Indonesia",
 "Geometry POLYGON((82.37018 -23.04163,202.62982 -23.04163,202.62982 25.04163,82.37018 25.04163,82.37018 -23.04163))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Miniopterus tristis (Waterhouse, 1845)",
 "Year 2004-2024"
 ]
}

 The dataset includes 1 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0075742-240626123714530/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.97vzr5
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "Geometry" : [
 "POLYGON ((144.830123 -36.982104, 144.830123 -36.98435, 144.832368 -36.98435, 144.832368 -36.982104, 144.830123 -36.982104))"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0075743-240626123714530/datasets/export for details.
DOI: 10.5517/ccdc.csd.cc2cnp80
title: CCDC 2194622: Experimental Crystal Structure Determination

description: Related Article: Yang-Yang Ju, Ling Chai, Kang Li, Jiang-Feng Xing, Xiao-Hui Ma, Zhen-Lin Qiu, Xin-Jing Zhao, Jun Zhu, Yuan-Zhi Tan|2023|J.Am.Chem.Soc.|145|2815|doi:10.1021/jacs.2c08746
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2cnp91
title: CCDC 2194623: Experimental Crystal Structure Determination

description: Related Article: Yang-Yang Ju, Ling Chai, Kang Li, Jiang-Feng Xing, Xiao-Hui Ma, Zhen-Lin Qiu, Xin-Jing Zhao, Jun Zhu, Yuan-Zhi Tan|2023|J.Am.Chem.Soc.|145|2815|doi:10.1021/jacs.2c08746
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2cnpb2
title: CCDC 2194624: Experimental Crystal Structure Determination

description: Related Article: Yang-Yang Ju, Ling Chai, Kang Li, Jiang-Feng Xing, Xiao-Hui Ma, Zhen-Lin Qiu, Xin-Jing Zhao, Jun Zhu, Yuan-Zhi Tan|2023|J.Am.Chem.Soc.|145|2815|doi:10.1021/jacs.2c08746
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2dr2kt
title: CCDC 2226716: Experimental Crystal Structure Determination

description: Related Article: Sebastian Obermann, Wenhao Zheng, Jason Melidonie, Steffen Böckmann, Silvio Osella, Nicolás Arisnabarreta, L. Andrés Guerrero-León, Felix Hennersdorf, David Beljonne, Jan J. Weigand, Mischa Bonn, Steven De Feyter, Michael Ryan Hansen, Hai I. Wang, Ji Ma, Xinliang Feng|2023|Chemical Science|14|8607|doi:10.1039/D3SC02824K
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2j62rl
title: CCDC 2329549: Experimental Crystal Structure Determination

description: Related Article: Matthew C. Risi, William Henderson, Graham C. Saunders|2024|Polyhedron|255|116992|doi:10.1016/j.poly.2024.116992
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.15468/dl.yke89r
title: Occurrence Download

description: A dataset containing 2865231 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Continent is Europe",
 "Geometry POLYGON((-10.48909 47.89352,60.08802 47.89352,60.08802 72.25884,-10.48909 72.25884,-10.48909 47.89352))",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Hemiptera",
 "Year 2000-2024"
 ]
}

 The dataset includes 2865231 records from 1835 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0075728-240626123714530/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.t7fap5
title: Occurrence Download

description: A dataset containing 5656 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Ostrea edulis Linnaeus, 1758)",
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil)"
 ]
 }
 },
 "Geometry POLYGON ((-12.62497 53.1001, 3.499824 53.1001, 3.499824 61.65918, -12.62497 61.65918, -12.62497 53.1001))"
 ]
}

 The dataset includes 5656 records from 50 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0032658-241107131044228/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.