cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.5718862
title: Effectiveness of preoperative decolonization with nasal povidone iodine in Chinese patients undergoing elective orthopedic surgery: a prospective cross-sectional study

description: Staphylococcus aureus colonization in the nares of patients undergoing elective orthopedic surgery increases the potential risk of surgical site infections. Methicillin-resistant S. aureus (MRSA) has gained recognition as a pathogen that is no longer only just a hospital-acquired pathogen. Patients positive for MRSA are associated with higher rates of morbidity and mortality following infection. MRSA is commonly found in the nares, and methicillin-sensitive S. aureus (MSSA) is even more prevalent. Recently, studies have determined that screening for this pathogen prior to surgery and diminishing staphylococcal infections at the surgical site will dramatically reduce surgical site infections. A nasal mupirocin treatment is shown to significantly reduce the colonization of the pathogen. However, this treatment is expensive and is currently not available in China. Thus, in this study, we first sought to determine the prevalence of MSSA/MSRA in patients undergoing elective orthopedic surgery in northern China, and then, we treated the positive patients with a nasal povidone-iodine swab. Here, we demonstrate a successful reduction in the colonization of S. aureus. We propose that this treatment could serve as a cost-effective means of eradicating this pathogen in patients undergoing elective orthopedic surgery, which might reduce the rate of surgical site infections.
DOI: 10.6084/m9.figshare.5718862.v1
title: Effectiveness of preoperative decolonization with nasal povidone iodine in Chinese patients undergoing elective orthopedic surgery: a prospective cross-sectional study

description: Staphylococcus aureus colonization in the nares of patients undergoing elective orthopedic surgery increases the potential risk of surgical site infections. Methicillin-resistant S. aureus (MRSA) has gained recognition as a pathogen that is no longer only just a hospital-acquired pathogen. Patients positive for MRSA are associated with higher rates of morbidity and mortality following infection. MRSA is commonly found in the nares, and methicillin-sensitive S. aureus (MSSA) is even more prevalent. Recently, studies have determined that screening for this pathogen prior to surgery and diminishing staphylococcal infections at the surgical site will dramatically reduce surgical site infections. A nasal mupirocin treatment is shown to significantly reduce the colonization of the pathogen. However, this treatment is expensive and is currently not available in China. Thus, in this study, we first sought to determine the prevalence of MSSA/MSRA in patients undergoing elective orthopedic surgery in northern China, and then, we treated the positive patients with a nasal povidone-iodine swab. Here, we demonstrate a successful reduction in the colonization of S. aureus. We propose that this treatment could serve as a cost-effective means of eradicating this pathogen in patients undergoing elective orthopedic surgery, which might reduce the rate of surgical site infections.
DOI: 10.6084/m9.figshare.5718859
title: Effect of atenolol pre-treatment in heart damage in a model of intestinal ischemia-reperfusion

description: Abstract Purpose: To investigate the effects of atenolol in inflammatory mediator and oxidative stress in a myocardial injury by intestinal ischemia/reperfusion in rat model. Methods: Adult Wistar male rats were randomly (n=8), anesthetized and divided in: Sham: submitted to operation only; group SS+IR: intravenous saline infusion following superior mesenteric artery occlusion during 60 minutes (ischemia) and open for 120 minutes (reperfusion); group AT+IR: intravenous atenolol infusion (2 mg/kg) following superior mesenteric artery occlusion during 60 minutes (ischemia) and open for 120 minutes (reperfusion); and group AT+I+AT+R: intravenous atenolol infusion following superior mesenteric artery occlusion during 60 minutes (ischemia) and in the time 45 minutes other atenolol doses were administrated and the artery was open for 120 minutes (reperfusion), all animals were submitted to muscular relaxation for mechanical ventilation. In the end of experiment the animals were euthanized and the hearts tissue were morphology analyzed by histology and malondialdehyde by ELISA, and the plasma were analyzed for tumor necrosis factor-alpha by ELISA. Results: The group SS+IR demonstrated the higher malondialdehyde levels when compared with the atenolol treated-groups (p=0.001) in the heart tissue. The tumor necrosis factor-alpha level in plasma decrease in the treated groups when compared with SS+IR group (p=0.001). Histology analyses demonstrate pyknosis, edema, cellular vacuolization, presence of inflammatory infiltrate and band contraction in the heart tissue of the rats. Conclusion: Atenolol significantly reduce the degree of cardiac damage after intestinal ischemia-reperfusion.
DOI: 10.6084/m9.figshare.5718859.v1
title: Effect of atenolol pre-treatment in heart damage in a model of intestinal ischemia-reperfusion

description: Abstract Purpose: To investigate the effects of atenolol in inflammatory mediator and oxidative stress in a myocardial injury by intestinal ischemia/reperfusion in rat model. Methods: Adult Wistar male rats were randomly (n=8), anesthetized and divided in: Sham: submitted to operation only; group SS+IR: intravenous saline infusion following superior mesenteric artery occlusion during 60 minutes (ischemia) and open for 120 minutes (reperfusion); group AT+IR: intravenous atenolol infusion (2 mg/kg) following superior mesenteric artery occlusion during 60 minutes (ischemia) and open for 120 minutes (reperfusion); and group AT+I+AT+R: intravenous atenolol infusion following superior mesenteric artery occlusion during 60 minutes (ischemia) and in the time 45 minutes other atenolol doses were administrated and the artery was open for 120 minutes (reperfusion), all animals were submitted to muscular relaxation for mechanical ventilation. In the end of experiment the animals were euthanized and the hearts tissue were morphology analyzed by histology and malondialdehyde by ELISA, and the plasma were analyzed for tumor necrosis factor-alpha by ELISA. Results: The group SS+IR demonstrated the higher malondialdehyde levels when compared with the atenolol treated-groups (p=0.001) in the heart tissue. The tumor necrosis factor-alpha level in plasma decrease in the treated groups when compared with SS+IR group (p=0.001). Histology analyses demonstrate pyknosis, edema, cellular vacuolization, presence of inflammatory infiltrate and band contraction in the heart tissue of the rats. Conclusion: Atenolol significantly reduce the degree of cardiac damage after intestinal ischemia-reperfusion.
DOI: 10.6084/m9.figshare.5718856
title: Assessment of watermelon accessions for salt tolerance using stress tolerance indices

description: ABSTRACT Salt stress is the most significant constraint for agricultural production in arid and semi-arid regions. Thus, genetically improved stress-tolerant varieties are needed for the future. The identification of salt-tolerant genotypes is the starting point for such breeding studies. This study was conducted to determine and assess the tolerance of different watermelon genotypes under saline conditions. Twenty-two watermelon genotypes and accessions were grown in pots with 3 kg of soil in four saline stress conditions (0 mmol kg-1 as the control, 25, 50 and 100 mmol kg-1 NaCl). The detrimental effects of salt stress on the plants were evident with increasing doses of NaCl. Stress indices calculated over the plant dry weights under the 100 mmol kg-1 salinity level were used to assess the salt tolerance of the genotypes. Stress intensity was calculated as 0.76. Such a value indicated that the highest dose of salt exerted severe stress on the plants. The G04, G14 and G21 genotypes were considered to be salt tolerant, since these genotypes showed the highest values of K/Na and Ca/Na ratios in the plant tissue. The losses in dry mass at severe salt stress reached 75.48%. In principal component analyses, the genotypes had positive correlations with stress tolerance indices of MP (mean productivity), GMP (geometric mean productivity) and STI (stress tolerance index). The GMP and STI indices indicated that G04 (a member of Citrullus colocynthis), G14 and G21 could be prominent sources to develop salt tolerance.
DOI: 10.6084/m9.figshare.5718856.v1
title: Assessment of watermelon accessions for salt tolerance using stress tolerance indices

description: ABSTRACT Salt stress is the most significant constraint for agricultural production in arid and semi-arid regions. Thus, genetically improved stress-tolerant varieties are needed for the future. The identification of salt-tolerant genotypes is the starting point for such breeding studies. This study was conducted to determine and assess the tolerance of different watermelon genotypes under saline conditions. Twenty-two watermelon genotypes and accessions were grown in pots with 3 kg of soil in four saline stress conditions (0 mmol kg-1 as the control, 25, 50 and 100 mmol kg-1 NaCl). The detrimental effects of salt stress on the plants were evident with increasing doses of NaCl. Stress indices calculated over the plant dry weights under the 100 mmol kg-1 salinity level were used to assess the salt tolerance of the genotypes. Stress intensity was calculated as 0.76. Such a value indicated that the highest dose of salt exerted severe stress on the plants. The G04, G14 and G21 genotypes were considered to be salt tolerant, since these genotypes showed the highest values of K/Na and Ca/Na ratios in the plant tissue. The losses in dry mass at severe salt stress reached 75.48%. In principal component analyses, the genotypes had positive correlations with stress tolerance indices of MP (mean productivity), GMP (geometric mean productivity) and STI (stress tolerance index). The GMP and STI indices indicated that G04 (a member of Citrullus colocynthis), G14 and G21 could be prominent sources to develop salt tolerance.
DOI: 10.6084/m9.figshare.5718850
title: PROGNOSTIC FACTORS IN PATIENTS WITH PRESSURE SORES IN A UNIVERSITY HOSPITAL IN SOUTHERN BRAZIL

description: ABSTRACT Objective: Despite advances in medical care, patients who are hospitalized or have spinal cord injuries often develop pressure sores. The objective of this study was to describe the epidemiological characteristics of pressure sores and evaluate factors associated with recurrence and cure. Methods: In this historical cohort study, clinical and laboratory data were collected from medical records between 1997 and 2016. Results: Sixty individuals with pressure ulcers were included; mean patient age was 38.1±16.5 (37.0) years, 83.3% were men, and 86.8% identified as white. Most patients (85.1%) had paraplegia, amputation, or trauma of the lower limbs with motor sequelae; the remainder (14.9%) were quadriplegic. Most (78.3%) underwent surgery, and the mean follow-up time was 1.8±2.5 years. The lesions were cured in 25 patients; they recurred in 25% of the patients, and recurrence was seen to be associated with the location of the lesions. Patients with recurrent lesions had more medical consultations and a longer treatment time. Individuals whose ulcers had healed had fewer lesions, higher body mass index (BMI), and a higher proportion of these patients underwent surgery. Conclusions: BMI and location and number of lesions are prognostic factors. Level of Evidence IV, Case Series.
DOI: 10.6084/m9.figshare.5718850.v1
title: PROGNOSTIC FACTORS IN PATIENTS WITH PRESSURE SORES IN A UNIVERSITY HOSPITAL IN SOUTHERN BRAZIL

description: ABSTRACT Objective: Despite advances in medical care, patients who are hospitalized or have spinal cord injuries often develop pressure sores. The objective of this study was to describe the epidemiological characteristics of pressure sores and evaluate factors associated with recurrence and cure. Methods: In this historical cohort study, clinical and laboratory data were collected from medical records between 1997 and 2016. Results: Sixty individuals with pressure ulcers were included; mean patient age was 38.1±16.5 (37.0) years, 83.3% were men, and 86.8% identified as white. Most patients (85.1%) had paraplegia, amputation, or trauma of the lower limbs with motor sequelae; the remainder (14.9%) were quadriplegic. Most (78.3%) underwent surgery, and the mean follow-up time was 1.8±2.5 years. The lesions were cured in 25 patients; they recurred in 25% of the patients, and recurrence was seen to be associated with the location of the lesions. Patients with recurrent lesions had more medical consultations and a longer treatment time. Individuals whose ulcers had healed had fewer lesions, higher body mass index (BMI), and a higher proportion of these patients underwent surgery. Conclusions: BMI and location and number of lesions are prognostic factors. Level of Evidence IV, Case Series.
DOI: 10.6084/m9.figshare.5718844
title: Passifloraceae sensu stricto from Parque Estadual Cachoeira da Fumaça, Espírito Santo, Brazil

description: Abstract The “Parque Estadual Cachoeira da Fumaça” (PECF) is located between Alegre and Ibitirama, region of Caparaó, South of Espírito Santo, protecting springs and remnants of a preserved section of the Braço Norte Direito river, affluent of the Itapemirim river. In this work, we are presented the species of Passifloraceae stricto sensu in the PECF. The family is represented for the genus Passiflora with six species: Passiflora alata, P. amethystina, P. capsularis, P. edulis, P. porophylla and P. speciosa. Descriptions, photos, geographic distribution data and palinotaxonomy, in addition taxonomic comments are presented.
DOI: 10.6084/m9.figshare.5718844.v1
title: Passifloraceae sensu stricto from Parque Estadual Cachoeira da Fumaça, Espírito Santo, Brazil

description: Abstract The “Parque Estadual Cachoeira da Fumaça” (PECF) is located between Alegre and Ibitirama, region of Caparaó, South of Espírito Santo, protecting springs and remnants of a preserved section of the Braço Norte Direito river, affluent of the Itapemirim river. In this work, we are presented the species of Passifloraceae stricto sensu in the PECF. The family is represented for the genus Passiflora with six species: Passiflora alata, P. amethystina, P. capsularis, P. edulis, P. porophylla and P. speciosa. Descriptions, photos, geographic distribution data and palinotaxonomy, in addition taxonomic comments are presented.
DOI: 10.6084/m9.figshare.5718841
title: The Indians in the cartography of Lusitanian America

description: Abstract Indigenous representations in the cartography of the colonial conquest of Lusitanian America and the Amazon were used to reinvent and locate Indigenous peoples. Often these representations were pictorial, with strong presence of figurative elements and ornaments, particularly seen in the maps produced between the sixteenth and the eighteenth centuries. However, in the Pombaline period (1750 - 1777) there were changes in cartographic representations - aesthetic values related to simplicity and symmetry in the composition of the maps began to stand out in place of ornamentation. Indigenous people are not featured very frequently in the cartographic production of the time, except when represented within the territory administratively defined by Pombaline reforms such as villages, parishes, settlements, farms, mills and plantations. The new Pombaline order intensified the processes of de-territorialization and re-territorialization of Indigenous societies in the Amazon, which came to relate to the Portuguese (and Spanish) colonial conquests in a different way. In this sense, the objective of this article is to discuss indigenous representations within the scope of space representation (designed space) of colonial Amazonia, through the investigation of colonial maps within the theoretical-methodological perspective of historical cartography.
DOI: 10.6084/m9.figshare.5718841.v1
title: The Indians in the cartography of Lusitanian America

description: Abstract Indigenous representations in the cartography of the colonial conquest of Lusitanian America and the Amazon were used to reinvent and locate Indigenous peoples. Often these representations were pictorial, with strong presence of figurative elements and ornaments, particularly seen in the maps produced between the sixteenth and the eighteenth centuries. However, in the Pombaline period (1750 - 1777) there were changes in cartographic representations - aesthetic values related to simplicity and symmetry in the composition of the maps began to stand out in place of ornamentation. Indigenous people are not featured very frequently in the cartographic production of the time, except when represented within the territory administratively defined by Pombaline reforms such as villages, parishes, settlements, farms, mills and plantations. The new Pombaline order intensified the processes of de-territorialization and re-territorialization of Indigenous societies in the Amazon, which came to relate to the Portuguese (and Spanish) colonial conquests in a different way. In this sense, the objective of this article is to discuss indigenous representations within the scope of space representation (designed space) of colonial Amazonia, through the investigation of colonial maps within the theoretical-methodological perspective of historical cartography.
DOI: 10.6084/m9.figshare.5718835
title: Quality of life and adherence to treatment in early-treated Brazilian phenylketonuria pediatric patients

description: Early dietary treatment of phenylketonuria (PKU), an inborn error of phenylalanine (Phe) metabolism, results in normal cognitive development. Although health-related quality of life (HRQoL) of PKU patients has been reported as unaffected in high-income countries, there are scarce data concerning HRQoL and adherence to treatment of PKU children and adolescents from Brazil. The present study compared HRQoL scores in core dimensions of Brazilian early-treated PKU pediatric patients with those of a reference population, and explored possible relationships between adherence to treatment and HRQoL. Early-treated PKU pediatric patient HRQoL was evaluated by self- and parent-proxy reports of the Pediatric Quality of Life Inventory (PedsQL) core scales. Adherence to treatment was evaluated by median Phe levels and percentage of results within the therapeutic target range in two periods. Means for total and core scales scores of PedsQL self- and parent proxy-reports of PKU patients were significantly lower than their respective means for controls. Adequacy of median Phe concentrations and the mean percentage of values in the target range fell substantially from the first year of life to the last year of this study. There was no significant difference in mean total and core scale scores for self- and parent proxy-reports between patients with adequate and those with inadequate median Phe concentrations. The harmful consequences for intellectual capacity caused by poor adherence to dietary treatment could explain the observed decrease in all HRQoL scales, especially in school functioning. Healthcare system and financial difficulties may also have influenced negatively all HRQoL dimensions.
DOI: 10.6084/m9.figshare.5718835.v1
title: Quality of life and adherence to treatment in early-treated Brazilian phenylketonuria pediatric patients

description: Early dietary treatment of phenylketonuria (PKU), an inborn error of phenylalanine (Phe) metabolism, results in normal cognitive development. Although health-related quality of life (HRQoL) of PKU patients has been reported as unaffected in high-income countries, there are scarce data concerning HRQoL and adherence to treatment of PKU children and adolescents from Brazil. The present study compared HRQoL scores in core dimensions of Brazilian early-treated PKU pediatric patients with those of a reference population, and explored possible relationships between adherence to treatment and HRQoL. Early-treated PKU pediatric patient HRQoL was evaluated by self- and parent-proxy reports of the Pediatric Quality of Life Inventory (PedsQL) core scales. Adherence to treatment was evaluated by median Phe levels and percentage of results within the therapeutic target range in two periods. Means for total and core scales scores of PedsQL self- and parent proxy-reports of PKU patients were significantly lower than their respective means for controls. Adequacy of median Phe concentrations and the mean percentage of values in the target range fell substantially from the first year of life to the last year of this study. There was no significant difference in mean total and core scale scores for self- and parent proxy-reports between patients with adequate and those with inadequate median Phe concentrations. The harmful consequences for intellectual capacity caused by poor adherence to dietary treatment could explain the observed decrease in all HRQoL scales, especially in school functioning. Healthcare system and financial difficulties may also have influenced negatively all HRQoL dimensions.
DOI: 10.6084/m9.figshare.5718832
title: Comparison of Arndt-endobronchial blocker plus laryngeal mask airway with left-sided double-lumen endobronchial tube in one-lung ventilation in thoracic surgery in the morbidly obese

description: This study aimed to evaluate the feasibility and performance of Arndt-endobronchial blocker (Arndt) combined with laryngeal mask airway (LMA) compared with left-sided double-lumen endobronchial tube (L-DLT) in morbidly obese patients in one-lung ventilation (OLV). In a prospective, randomized double-blind controlled clinical trial, 80 morbidly obese patients (ASA I-III, aged 20–70) undergoing general anesthesia for elective thoracic surgeries were randomly allocated into groups Arndt (n=40) and L-DLT (n=40). In group Arndt, a LMA™ Proseal was placed followed by an Arndt-endobronchial blocker. In group L-DLT, patients were intubated with a left-sided double-lumen endotracheal tube. Primary endpoints were the airway establishment, ease of insertion, oxygenation, lung collapse and surgical field exposure. Results showed similar ease of airway establishment and tube/device insertion between the two groups. Oxygen arterial pressure (PaO2) of patients in the Arndt group was significantly higher than L-DLT (154±46 vs 105±52 mmHg; P&lt;0.05). Quality of lung collapse and surgical field exposure in the Arndt group was significantly better than L-DLT (effective rate 100 vs 90%; P&lt;0.05). Duration of surgery and anesthesia were significantly shorter in the Arndt group (2.4±1.7 vs 3.1±1.8 and 2.8±1.9 vs 3.8±1.8 h, respectively; P&lt;0.05). Incidence of hoarseness of voice and incidence and severity of throat pain at the post-anesthesia care unit and 12, 24, 48, and 72 h after surgery were significantly lower in the Arndt group (P&lt;0.05). Findings suggested that Arndt-endobronchial blocker combined with LMA can serve as a promising alternative for morbidly obese patients in OLV in thoracic surgery.