cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.12059439
title: Chaetoceros affinis draft genome assembly

description: Thes is a draft genome of Chaetoceros affinis based on two strains isolated from the Canary Islands, assembled with Platanus. The genome assembly was performed to locate microsatellite loci and is in a draft stage. Raw data can be found on NCBI SRA under ID PRJNA622510.
DOI: 10.6084/m9.figshare.12059436.v1
title: data.xlsx

description: In the file, the data points in spectrum is measured by a USB2000-VIS-NIR-ES spectrometer. The measurement system adopts the diffuse reflection mode with a spectrum range of 957.03–1727.23 nm, with each spectrum having 477 data points. The hardness data is measured by texture analyzer (TA.XT. plus, Stable Micro Systems, UK) and a P100 probe.<br>
DOI: 10.6084/m9.figshare.12059439.v1
title: Chaetoceros affinis draft genome assembly

description: Thes is a draft genome of Chaetoceros affinis based on two strains isolated from the Canary Islands, assembled with Platanus. The genome assembly was performed to locate microsatellite loci and is in a draft stage. Raw data can be found on NCBI SRA under ID PRJNA622510.
DOI: 10.6084/m9.figshare.12059493.v3
title: Melatonin binding assay by Acellera

description: Filtered trajectories of the melatonin binding assay against main protease of SARS-CoV-2 (PDB ID: 6YB7), provided by Acellera.<br>
DOI: 10.6084/m9.figshare.12059493.v2
title: Melatonin binding assay by Acellera

description: Filtered trajectories of the melatonin binding assay against main protease of SARS-CoV-2 (PDB ID: 6YB7), provided by Acellera.<br>
DOI: 10.25392/leicester.data.12059376
title: Data to accompany: The development of a quality of life scale for informal carers for older adults.

description: Data to accompany: The development of a quality of life scale for informal carers for older adults. (Zipped file)Published in: Gerontology and Geriatric Medicine.<br><b>Abstract</b><b>Background.</b> The aim of the study was to develop a multi-dimensional quality of life instrument suitable for use among individuals across cultures who have an informal care role for older persons.<b>Methods.</b> Participants were informal carers of older adults in the UK (<i>n</i>=308), USA (<i>n</i>=164), and China (<i>n</i>=131). We carried out exploratory and confirmatory factor analyses of 61 items derived from the eight-factor Adult Carers Quality of Life questionnaire with newly added items to define both traditional and non-traditional informal care roles.<b>Results.</b> Findings suggest a 24-item quality of life scale with a six-factor structure to caring for older adults that assesses (1) exhaustion, (2) adoption of a traditional carer role, (3) personal growth, (4) management and performance, (5) level of support, and (6) financial matters.<b>Conclusion.</b> We present a new scale to assess the multi-dimensional aspects of quality of life among those caring for older adults.
DOI: 10.25392/leicester.data.12059376.v1
title: Data to accompany: The development of a quality of life scale for informal carers for older adults.

description: Data to accompany: The development of a quality of life scale for informal carers for older adults. (Zipped file)Published in: Gerontology and Geriatric Medicine.<br><b>Abstract</b><b>Background.</b> The aim of the study was to develop a multi-dimensional quality of life instrument suitable for use among individuals across cultures who have an informal care role for older persons.<b>Methods.</b> Participants were informal carers of older adults in the UK (<i>n</i>=308), USA (<i>n</i>=164), and China (<i>n</i>=131). We carried out exploratory and confirmatory factor analyses of 61 items derived from the eight-factor Adult Carers Quality of Life questionnaire with newly added items to define both traditional and non-traditional informal care roles.<b>Results.</b> Findings suggest a 24-item quality of life scale with a six-factor structure to caring for older adults that assesses (1) exhaustion, (2) adoption of a traditional carer role, (3) personal growth, (4) management and performance, (5) level of support, and (6) financial matters.<b>Conclusion.</b> We present a new scale to assess the multi-dimensional aspects of quality of life among those caring for older adults.
DOI: 10.6084/m9.figshare.12059358
title: README.txt

description: Readme file<br>
DOI: 10.6084/m9.figshare.12059358.v1
title: README.txt

description: Readme file<br>
DOI: 10.6084/m9.figshare.12059319
title: Calf_experiment.mat

description: Ultrasound raw data associated to the calf experiment<br>
DOI: 10.6084/m9.figshare.12059229
title: Plexiglas_experiments__raw-data.mat

description: Ultrasound raw data associated to the plexiglas experiment<br>
DOI: 10.6084/m9.figshare.12059229.v1
title: Plexiglas_experiments__raw-data.mat

description: Ultrasound raw data associated to the plexiglas experiment<br>
DOI: 10.6084/m9.figshare.12059046
title: Table S1: GDGT compositions across all experiment conditions and sampling times

description: Table S1 Notes. GDGT relative abundances are given as percent of total GDGT quantified. In the O<sub>2</sub> column, “Air” describes experiments without gas sparge, and 0.2* is describes the serially transferred 0.2% O<sub>2</sub> gas-fed batch experiment. ES and LL in the Phase column describe Early Stationary and Late Log phase sampling respectively.<br>
DOI: 10.6084/m9.figshare.12058962
title: Daily SST measured at 8 wave-exposed intertidal locations along the Nova Scotia coast (May 2015 to June 2017)

description: Daily values of sea surface temperature (SST) measured between 01 May 2015 and 21 June 2017 at 8 wave-exposed locations along the Atlantic coast of Nova Scotia, Canada.
DOI: 10.6084/m9.figshare.12058944
title: Supporting data

description: Raw data and Figures
DOI: 10.6084/m9.figshare.12058962.v1
title: Daily SST measured at 8 wave-exposed intertidal locations along the Nova Scotia coast (May 2015 to June 2017)

description: Daily values of sea surface temperature (SST) measured between 01 May 2015 and 21 June 2017 at 8 wave-exposed locations along the Atlantic coast of Nova Scotia, Canada.
DOI: 10.6084/m9.figshare.12058944.v1
title: Supporting data

description: Raw data and Figures
DOI: 10.6084/m9.figshare.12059046.v1
title: Table S1: GDGT compositions across all experiment conditions and sampling times

description: GDGT relative abundances. In the O<sub>2</sub> column, “Atmospheric” is used to describe experiments without gas sparge, and 0.2* is used to describe the serially transferred 0.2% O<sub>2</sub> gas-fed batch experiment. ES and LL in the Phase column describe Early Stationary and Late Log phase sampling respectively.
DOI: 10.6084/m9.figshare.12058854
title: Winter and spring conditions determine the production of the salvinia weevil mass rearing programme

description: Invasion from giant salvinia (<i>Salvinia molesta</i> Mitchell, Salviniaceae) blocks sunlight entering waterbodies, reducing submerged aquatic macrophytes, thus lowering dissolved oxygen and stressing aquatic organisms. Due to its rapid growth and ease of dispersal through fragmentation, giant salvinia can quickly become problematic and difficult to eradicate. Since invasion of giant salvinia is persistent, land managers need a cost-effective method of control. Biological control by the salvinia weevil (<i>Cyrtobagous salviniae</i> Calder and Sands, Coleoptera: Curculionidae) has proven successful in controlling giant salvinia, and at a fraction of the cost of chemical and mechanical control. To maintain a source of salvinia weevils for field releases, mass rearing in outdoor ponds by natural resource managers is common practice in tropical regions. Using number of freezing hours and degree-day calculator, we examined how winter and spring conditions impacted the production of weevils in mass rearing ponds across southern Louisiana, USA. We found that winter temperature determined adult weevil mortality while spring temperature dictated reproduction, larval appearance, and timing of pond harvest. During winters with &lt;55 h of freezing temperatures, ponds maintained densities of at least 13 adult salvinia weevils kg<sup>−1</sup>. Winter with &gt;200 hours of freezing temperature reduced adult density in the ponds nearly extirpating the population. Larvae were found on samples on average at 89 degree-days which began accumulating in January 1st. This study suggested that winter and spring conditions are critical for mass rearing operations and population growth of <i>C. salviniae</i>.
DOI: 10.6084/m9.figshare.12058854.v1
title: Winter and spring conditions determine the production of the salvinia weevil mass rearing programme

description: Invasion from giant salvinia (<i>Salvinia molesta</i> Mitchell, Salviniaceae) blocks sunlight entering waterbodies, reducing submerged aquatic macrophytes, thus lowering dissolved oxygen and stressing aquatic organisms. Due to its rapid growth and ease of dispersal through fragmentation, giant salvinia can quickly become problematic and difficult to eradicate. Since invasion of giant salvinia is persistent, land managers need a cost-effective method of control. Biological control by the salvinia weevil (<i>Cyrtobagous salviniae</i> Calder and Sands, Coleoptera: Curculionidae) has proven successful in controlling giant salvinia, and at a fraction of the cost of chemical and mechanical control. To maintain a source of salvinia weevils for field releases, mass rearing in outdoor ponds by natural resource managers is common practice in tropical regions. Using number of freezing hours and degree-day calculator, we examined how winter and spring conditions impacted the production of weevils in mass rearing ponds across southern Louisiana, USA. We found that winter temperature determined adult weevil mortality while spring temperature dictated reproduction, larval appearance, and timing of pond harvest. During winters with &lt;55 h of freezing temperatures, ponds maintained densities of at least 13 adult salvinia weevils kg<sup>−1</sup>. Winter with &gt;200 hours of freezing temperature reduced adult density in the ponds nearly extirpating the population. Larvae were found on samples on average at 89 degree-days which began accumulating in January 1st. This study suggested that winter and spring conditions are critical for mass rearing operations and population growth of <i>C. salviniae</i>.
DOI: 10.6084/m9.figshare.12058821
title: Abundance of seaweeds and sessile invertebrates at the high and mid-intertidal zones in wave-exposed habitats along the Nova Scotia coast (2017)

description: Percent cover of seaweeds and sessile invertebrates measured in the summer of 2017 at the high and mid-intertidal zones in wave-exposed rocky habitats along the Atlantic coast of Nova Scotia, Canada.
DOI: 10.6084/m9.figshare.12058728
title: CBX8 phosphorylation.xlsx

description: 我们进行了CBX8的体外磷酸化，并使用质谱法鉴定了PKD1-CA磷酸化了CBX8的哪个残基。质谱分析了包括Ser219，Ser236和Ser256在内的三个磷酸化丝氨酸位点
DOI: 10.6084/m9.figshare.12058821.v1
title: Abundance of seaweeds and sessile invertebrates at the high and mid-intertidal zones in wave-exposed habitats along the Nova Scotia coast (2017)

description: Percent cover of seaweeds and sessile invertebrates measured in the summer of 2017 at the high and mid-intertidal zones in wave-exposed rocky habitats along the Atlantic coast of Nova Scotia, Canada.
DOI: 10.6084/m9.figshare.12058656.v2
title: data for MS-AFSC-Nonadditive effects of decomposing mixed foliar litter on the release of several metallic elements in a Pinus massoniana Lamb. forest.xlsx

description: data for MS-AFSC-Nonadditive effects of decomposing mixed foliar litter on the release of several metallic elements in a Pinus massoniana Lamb. forest<br>The objectives of this study were 1) to assess the potential nonadditive effects of mixed leaf litter on the release of multiple metallic elements during decomposition and 2) to explore the relationship of the potential mixing effect and the changing litter quality (i.e., C, N, P and metallic elements) with environmental hydrothermal dynamics. <br>
DOI: 10.6084/m9.figshare.12058656.v1
title: data for MS-AFSC-Nonadditive effects of decomposing mixed foliar litter on the release of several metallic elements in a Pinus massoniana Lamb. forest.xlsx

description: data for MS-AFSC-Nonadditive effects of decomposing mixed foliar litter on the release of several metallic elements in a Pinus massoniana Lamb. forest
DOI: 10.6084/m9.figshare.12058449
title: A biographical sketch of Troy D. Zars (1967–2018)

description: Troy D. Zars (1967–2018) was an American biologist. He studied the relationships between genes, neuronal circuits and behavior in the fruit fly <i>Drosophila melanogaster</i>. Zars co-pioneered the use of transgene expression to locally restore gene function in memory-defective fly mutants, an approach that provided breakthrough insights into the localization of memory traces in the fly brain. With ensuing refinements of the methods of transgene expression and the broadening in the range of transgenes to be expressed, this shaped the field of modern behavioral neurogenetics.
DOI: 10.6084/m9.figshare.12058449.v1
title: A biographical sketch of Troy D. Zars (1967–2018)

description: Troy D. Zars (1967–2018) was an American biologist. He studied the relationships between genes, neuronal circuits and behavior in the fruit fly <i>Drosophila melanogaster</i>. Zars co-pioneered the use of transgene expression to locally restore gene function in memory-defective fly mutants, an approach that provided breakthrough insights into the localization of memory traces in the fly brain. With ensuing refinements of the methods of transgene expression and the broadening in the range of transgenes to be expressed, this shaped the field of modern behavioral neurogenetics.
DOI: 10.6084/m9.figshare.12058230
title: Family history of cardiovascular disease and risk of premature coronary heart disease: A matched case-control study

description: <b>Background</b> Self-reported family history of cardiovascular disease (CVD) is an independent risk factor for future coronary heart disease (CHD) events. However, inclusion of family history of CVD in the traditional risk scores failed to improve risk prediction of CHD. It is proposed that family history of CVD may substantially increase the risk of CHD among younger individuals. <b></b> <b>Methodology</b> We conducted a matched case-control study with 170 hospital-based premature CHD patients (&lt;55 years in men and &lt;65 years in women) from a tertiary care centre in Thiruvananthapuram, Kerala and age and sex matched community-based controls in 1:1 ratio. Conditional logistic regression analysis was conducted to assess the independent association of family history of cardiovascular disease (CVD) and premature CHD. We estimated McNemar's odds ratios and their 95 percent confidence intervals. <b>Result</b> The prevalence of any family history of CVD and CHD in the control population was 24% and 21%, respectively. The family history of CVD was independently associated with premature CHD (OR = 9.0; 95%CI 4.7 – 17.3). There was a dose response relationship between family history and premature CHD as the risk increased linearly with increase in number of affected family members. <b>Conclusion</b> Family history of CVD is an independent risk factor for premature CHD. The risk of premature CHD increases linearly with increase in number of affected family members. Collecting family history beyond parental history of CVD is important for risk stratification. Targeting young individuals with family history of CVD for intensive risk reduction interventions may help to prevent future events.
DOI: 10.6084/m9.figshare.12058230.v1
title: Family history of CVD and risk of premature CHD study data

description: The following data set was utilized in the article: "Family history of cardiovascular disease and risk of premature coronary heart disease: A matched case-control study".
DOI: 10.6084/m9.figshare.12058230.v2
title: Family history of cardiovascular disease and risk of premature coronary heart disease: A matched case-control study

description: The following data set was utilized in the article: "Family history of cardiovascular disease and risk of premature coronary heart disease: A matched case-control study".
DOI: 10.25375/uct.12058164
title: Impact data of some youth who applied for the Chrysalis Academy

description: This data was obtained from some youth from Cape Town who applied for the Chrysalis Academy programme; both those who were selected and completed the programme and those who were not selected into the programme. <br><br>It includes post programme data about the outcomes of these individuals. The data was used in a formative evaluation of the programme to assess the impact of the programme.<br>The CA programme is geared to help youth in the Western Cape develop the skills and resilience needed to transcend the prevailing poverty, inequality, unemployment and crime in their communities. <br><br>Chrysalis offers a 3-month residential and 5 year After-Care programme for NEET youth aged 18-25 that includes life and vocational skills training as well as counselling and community service. <br><br>The programme also includes a 2-week outdoor/wilderness component that is deemed crucial to the success of the programme.<br>This data was acquired between 2018 and 2019.<br>
DOI: 10.25375/uct.12058164.v1
title: Impact data of some youth who applied for the Chrysalis Academy

description: This data was obtained from some youth from Cape Town who applied for the Chrysalis Academy programme; both those who were selected and completed the programme and those who were not selected into the programme. <br><br>It includes post programme data about the outcomes of these individuals. The data was used in a formative evaluation of the programme to assess the impact of the programme.<br>The CA programme is geared to help youth in the Western Cape develop the skills and resilience needed to transcend the prevailing poverty, inequality, unemployment and crime in their communities. <br><br>Chrysalis offers a 3-month residential and 5 year After-Care programme for NEET youth aged 18-25 that includes life and vocational skills training as well as counselling and community service. <br><br>The programme also includes a 2-week outdoor/wilderness component that is deemed crucial to the success of the programme.<br>This data was acquired between 2018 and 2019.<br>
DOI: 10.6084/m9.figshare.12058230.v3
title: Family history of cardiovascular disease and risk of premature coronary heart disease: A matched case-control study

description: <b>Background</b> Self-reported family history of cardiovascular disease (CVD) is an independent risk factor for future coronary heart disease (CHD) events. However, inclusion of family history of CVD in the traditional risk scores failed to improve risk prediction of CHD. It is proposed that family history of CVD may substantially increase the risk of CHD among younger individuals. <b></b> <b>Methodology</b> We conducted a matched case-control study with 170 hospital-based premature CHD patients (&lt;55 years in men and &lt;65 years in women) from a tertiary care centre in Thiruvananthapuram, Kerala and age and sex matched community-based controls in 1:1 ratio. Conditional logistic regression analysis was conducted to assess the independent association of family history of cardiovascular disease (CVD) and premature CHD. We estimated McNemar's odds ratios and their 95 percent confidence intervals. <b>Result</b> The prevalence of any family history of CVD and CHD in the control population was 24% and 21%, respectively. The family history of CVD was independently associated with premature CHD (OR = 9.0; 95%CI 4.7 – 17.3). There was a dose response relationship between family history and premature CHD as the risk increased linearly with increase in number of affected family members. <b>Conclusion</b> Family history of CVD is an independent risk factor for premature CHD. The risk of premature CHD increases linearly with increase in number of affected family members. Collecting family history beyond parental history of CVD is important for risk stratification. Targeting young individuals with family history of CVD for intensive risk reduction interventions may help to prevent future events.
DOI: 10.6084/m9.figshare.12058101
title: Supplementary Material for: Myofibroblast-Derived Exosomes Contribute to Development of a Susceptible Substrate for Atrial Fibrillation

description: <b><i>Objective:</i></b> Atrial fibrosis plays a critical role in atrial fibrillation (AF). A key event in the pathogenesis of fibrosis is the activation of fibroblasts (FBs) into myofibroblasts (MFBs). Paracrine factors released from MFBs lead to ion channel expression changes in cardiomyocytes (CMs). Downregulation of L-type calcium channel Ca<sub>v</sub>1.2 expression is a hallmark of AF-associated ionic remodeling. However, whether exosome (Exo)-mediated crosstalk between MFBs and CMs regulates Ca<sub>v</sub>1.2 expression remains unknown. <b><i>Methods:</i></b> Atrial FBs and CMs were isolated and cultured from neonatal rats by enzymatic digestion. The activation of FBs into MFBs was induced by angiotensin II. Co-culture assay and in vitro Exo treatment were used to determine the effect of MFB-derived Exos on Ca<sub>v</sub>1.2 expression. Confocal Ca<sup>2+</sup> imaging was performed to examine the adrenergic stimulation-elicited Ca<sup>2+</sup> influx signals. The levels of potential Ca<sub>v</sub>1.2-inhibitory microRNAs (miRNAs) were measured by qRT-PCR. <b><i>Results:</i></b> Untreated FBs expressed limited amounts of alpha smooth muscle actin (α-SMA), while angiotensin II induced a significant upregulation of α-SMA-expressing MFBs. Co-cultures of MFBs and CMs resulted in downregulation of Ca<sub>v</sub>1.2 expression in CMs, which was largely abolished by pretreatment of MFBs with exosomal inhibitor GW4869. More importantly, treatment with MFB-derived Exos caused repression of Ca<sub>v</sub>1.2 expression in CMs. Additionally, the adrenergic receptor agonist-elicited Ca<sup>2+</sup> influx signals in CMs were remarkably attenuated by pretreatment with MFB-derived Exos, corresponding to the paralleled change in Ca<sub>v</sub>1.2 expression. Finally, miR-21-3p, a potential Ca<sub>v</sub>1.2-inhibitory miRNA, was enriched in MFB-derived Exos and upregulated in CMs in response to MFB-derived Exos. <b><i>Conclusion:</i></b> We uncover an Exo-mediated crosstalk between MFBs and CMs, contributing to increased vulnerability to AF by reducing the expression of Ca<sub>v</sub>1.2 in CMs.
DOI: 10.6084/m9.figshare.12058089
title: Wave fetch GIS layers for Australia at 100m scale

description: This data layer gives values of summed wave fetch in 32 angular sectors around focal cells, using a model modified from that given in Burrows et al (2012 - see reference). Wave fetch is the distance to the nearest land in a defined direction. The model performs a three-scale search for land around each cell in the model, sparsely (every 10km) up to 200km, every 1km up to 20km away, and every 100m up to 1km distant. Fetch is calculated up to 5km from the coastline.<br>Values represent the summed number of grid cells to the nearest land across all 32 11.5° sectors. The file is a GeoTIFF using the WGS84 projection.