cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.8196840
title: Donor-acceptor complex formation by social self-sorting of polycyclic aromatic hydrocarbons and perylene bisimides

description: Additional data to report https://doi.org/10.1039/D3CC03704E Self-assembly versus complexation with polycyclic aromatic hydrocarbon (PAH) guest molecules is studied for a series of perylene bisimides (PBIs). Bulky imide substituents at the PBI guide their self-assembly into dimer aggregates with null-type exciton coupling. Host-guest titration experiments with perylene and triphenylene PAHs afford 1:1 and 1:2 complexes whose properties are studied by single crystal X-ray analysis and UV/Vis and fluorescence spectroscopy.
description: Additional data to report: https://doi.org/10.1039/D3CC03704E
DOI: 10.17864/1947.000491
title: Computer code for 'Ecological determinants of Cope's rule and its inverse'

description: This dataset includes a computer code written in MATLAB required to run the eco-evolutionary model with two adaptive traits presented in Roy et al. (2023, Communications Biology). The code includes an executable programme, and four MATLAB subroutines that need to be called in within the programme to run the model. This code can be adapted to generate the evolutionary trajectories and outcome of the model under user-defined parameter combinations and scenarios described in details in Roy et al. (2023).
DOI: 10.6084/m9.figshare.24118215
title: MV Kron-RLS

description: MV Kron-RLS
DOI: 10.6084/m9.figshare.24118215.v1
title: MV Kron-RLS

description: MV Kron-RLS
DOI: 10.6084/m9.figshare.24118206
title: Which modality is best for delivering an imagery script? Evidence for desirable difficulty effect

description: Data for my research
DOI: 10.6084/m9.figshare.24118206.v1
title: Which modality is best for delivering an imagery script? Evidence for desirable difficulty effect

description: Data for my research
DOI: 10.5281/zenodo.8334550
title: The data of "A comparison of citation-based clustering and topic modeling for science mapping"

description: These files consist of the data used in "A comparison of citation-based clustering and topic modeling for science mapping".
DOI: 10.5281/zenodo.8334551
title: The data of "A comparison of citation-based clustering and topic modeling for science mapping"

description: These files consist of the data used in "A comparison of citation-based clustering and topic modeling for science mapping".
DOI: 10.6092/unibo/amsacta/6854
title: MAIA Stroke Patients Interviews

description: The dataset contains the post-stroke patients’ and caregivers’ interviews carried out during the Horizon 2020 MAIA project to explore the impact of motor disability on their lives, previous experiences with assistive technologies, opinions, and attitudes about MAIA and their needs.
DOI: 10.6084/m9.figshare.23796594
title: Open Innovation Data.csvOpen Innovation Frameworks: A diagnostic analysis of deployment, engagement, evaluation, and governance of Open Innovation in SMEsOpen innovation frameworks: a diagnostic analysis of deployment, engagement, evaluation, and governance of open innovation in Small and medium-sized enterprises

description: The primary data from SMEs was gathered via a survey. SME managers who own or operate in the industries were the primary respondents, utilising a survey to gather primary data from SMEs
DOI: 10.6084/m9.figshare.23796594.v1
title: Open Innovation Data.csvOpen Innovation Frameworks: A diagnostic analysis of deployment, engagement, evaluation, and governance of Open Innovation in SMEsOpen innovation frameworks: a diagnostic analysis of deployment, engagement, evaluation, and governance of open innovation in Small and medium-sized enterprises

description: The primary data from SMEs was gathered via a survey. SME managers who own or operate in the industries were the primary respondents, utilising a survey to gather primary data from SMEs
DOI: 10.6084/m9.figshare.23936067
title: ARRIVE checklist

description: The ARRIVE 2.0 Checklist for “Co-rotating twin screw process for continuous manufacturing of solid crystal suspension: A promising strategy to enhance the solubility, permeation and oral bioavailability of Carvedilol”
DOI: 10.6084/m9.figshare.23936067.v3
title: ARRIVE checklist

description: The ARRIVE 2.0 Checklist for “Co-rotating twin screw process for continuous manufacturing of solid crystal suspension: A promising strategy to enhance the solubility, permeation and oral bioavailability of Carvedilol”
DOI: 10.6084/m9.figshare.23936067.v2
title: ARRIVE checklist

description: The ARRIVE 2.0 Checklist for “Co-rotating twin screw process for continuous manufacturing of solid crystal suspension: A promising strategy to enhance the solubility, permeation and oral bioavailability of Carvedilol”
DOI: 10.5281/zenodo.8125029
title: Raw data and analysis code of Transfusion model

description: Raw data and analysis code of the paper entitled Development and External Validation of a Model Based on Electronic Health Records to Predict Minor, or Moderate, and Major Transfusion During On-pump Cardiac Surgery
DOI: 10.5281/zenodo.8125030
title: Raw data and analysis code of Transfusion model

description: Raw data and analysis code of the paper entitled Development and External Validation of a Model Based on Electronic Health Records to Predict Minor, or Moderate, and Major Transfusion During On-pump Cardiac Surgery
DOI: 10.5281/zenodo.8125003
title: Raw data and analysis code of Transfusion model

description: Raw data and analysis code of the paper entitled Development and External Validation of a Model Based on Electronic Health Records to Predict Minor, or Moderate, and Major Transfusion During On-pump Cardiac Surgery
DOI: 10.5281/zenodo.8125002
title: Raw data and analysis code of Transfusion model

description: Raw data and analysis code of the paper entitled Development and External Validation of a Model Based on Electronic Health Records to Predict Minor, or Moderate, and Major Transfusion During On-pump Cardiac Surgery
DOI: 10.48677/f07e4ad2-9c08-4279-b688-c4c92e5c6996
title: Test-Metadatensatz

description: Hier wird eine kurze Zusammenfassung angegeben. Diese Beschreibung soll dem Benutzer in einem kurzen Text ein Verständnis für den Inhalt des Datensatzes bieten. Es soll in ganzen Sätzen in einfacher Form mitgeteilt werden, was die Daten darstellen, für welchen Zweck sie geschaffen wurden und wie diese Daten genutzt werden sollten.
DOI: 10.6084/m9.figshare.23905143.v1
title: Supplementary Material for: Geometric versus hemodynamic indexes for rupture-destined aneurysms: a retrospective cohort and a repeated-measures study

description: Introduction: A proper stratification of intracranial aneurysms is critical in identifying rupture-destined aneurysms and unruptured intracranial aneurysms. We aimed to determine the utility of geometric and hemodynamic indexes in differentiating two types of aneurysms, and to examine the characteristics of natural evolutionary changes of unruptured aneurysms. Methods: Rupture-destined aneurysm refers to an aneurysm that undergoes subsequent aneurysmal subarachnoid hemorrhage (SAH). On the other hand, an unruptured intracranial aneurysm is characterized by an aneurysm that does not experience rupture during serial time-of-flight magnetic resonance angiography (TOF-MRA). In addition to geometric indexes, signal intensity gradient (SIG), an in-vivo approximated wall shear stress from TOF-MRA, was measured in aneurysms. The difference between the maximum and minimum values of SIG in an aneurysm compared to parent arterial values was designated as the delta-SIG ratio. Results: This study analyzed 20 rupture-destined aneurysms in 20 patients and 45 unruptured intracranial aneurysms in 41 patients with follow-up TOF-MRA. While geometric indexes did not show differences between the two groups, the delta-SIG ratio was higher in the rupture-destined aneurysms (1.5±0.6 vs. 1.1±0.3, P=0.032). The delta-SIG ratio showed a higher area under the receiver operating characteristics curve for SAH than the size ratio (0.72 [95% CI, 0.58–0.87] vs. 0.56 [95% CI, 0.41–0.72], P=0.033). The longitudinal re-examination of TOF-MRA in the unruptured intracranial aneurysms revealed evidence of aneurysmal growth, while concurrently exhibiting hemodynamic stability. Discussion/Conclusion: The delta-SIG ratio showed higher discriminatory results between the two groups compared to geometric indexes. Aneurysmal rupture risk should be assessed by considering both geometric and hemodynamic information. This study was registered on ClinicalTrials.gov (NCT05450939).
DOI: 10.5281/zenodo.8334634
title: Information Status Indicator

description: A .csv table containing the results os all three information status sub-indicators, and the final information status indicator for all regions listed in GRIIS, considering alien amphibian species.
DOI: 10.5281/zenodo.8334633
title: Information Status Indicator

description: A .csv table containing the results os all three information status sub-indicators, and the final information status indicator for all regions listed in GRIIS, considering alien amphibian species.
DOI: 10.6084/m9.figshare.23832201.v1
title: Supplementary Material for: Effects of different exercises on physical function, dialysis adequacy, and health-related quality of life in maintenance hemodialysis patients: A systematic review and network meta-analysis

description: Background: Clinical guidelines recommend exercise training for patients undergoing maintenance hemodialysis (MHD). However, the effectiveness of different types of exercise remains uncertain. Objectives: To compare and rank the effect of different types of exercise on walking capacity, cardiorespiratory fitness, dialysis adequacy, and health-related quality of life (HRQOL) in patients undergoing MHD. Methods: Eight databases (four English and four Chinese) were searched from inception to January 1, 2022. Randomized controlled trials evaluating the efficacy of different exercises for patients undergoing MHD were included. Two independent reviewers screened the literature, extracted data, assessed the risk of bias, and evaluated the certainty of evidence. A frequentist random-effect network meta-analysis was conducted. Results: Ninety trials with 4,084 participants comparing 15 types of exercise were included, reporting on the six-minute walking test (45 trials), peak oxygen uptake (22 trials), dialysis adequacy (30 trials), and HRQOL (23 trials). Network meta-analysis showed that the most effective intervention for walking capacity was intradialytic aerobic exercise combined with blood flow restriction with a mean difference and 95% confidence interval of 97.35 [11.89-182.81], for peak oxygen uptake it was non-intradialytic combined aerobic and resistance exercise (4.35 [2.25-6.44]), for dialysis adequacy it was intradialytic combined aerobic and resistance exercise (0.17 [0.06-0.28]), for the physical component summary of HRQOL it was intradialytic aerobic exercise (4.93 [2.31-7.54]), and for the mental component summary of HRQOL it was non-intradialytic combined aerobic and resistance exercise (6.36 [0.45-12.27]). Ultimately, intradialytic combined aerobic and resistance exercise could improve all the above outcomes compared to usual care. Conclusions: This study concluded that intradialytic combined aerobic and resistance exercise is optimal for MHD patients due to its significant positive effects on multiple outcomes. Walking capacity can be further enhanced by combining blood flow restriction with exercise. For improving dialysis adequacy, intradialytic exercise proves to be more effective than non-intradialytic exercise. Further well-designed clinical trials are needed to investigate the effects of exercise with varying durations, intensities, and frequencies.
DOI: 10.6084/m9.figshare.23212940.v1
title: Systematic distributions of interaction strengths across tree interaction networks yield positive diversity-productivity relationships

description: Interaction strength of trees in suptropical forest and all the parameters estimated from the model used in the manuscript.
DOI: 10.6084/m9.figshare.23804019
title: Supplementary Material for: Circadian clock genes are regulated by rhythmic corticosterone at physiological levels in the rat hippocampus

description: Introduction: In the hippocampus, clock gene expression is important for memory and mood; however, the signaling mechanism controlling clock gene expression in the hippocampus is unknown. Recent findings suggest that circadian glucocorticoid rhythms driven by the suprachiasmatic nucleus (SCN) control rhythmic clock gene expression in neurons; in addition, dexamethasone modulates hippocampal clock gene expression. We therefore hypothesized that oscillations of clock genes in the hippocampus could be driven by SCN-controlled circadian rhythms in glucocorticoids. Methods: Temporal profiles of hippocampal clock gene expression were established by qRT-PCR on rat hippocampi, while cellular distribution was established by in situ hybridization. To determine the effect of rhythmic glucocorticoids on hippocampal clock gene expression, the SCN was lesioned, adrenal glands removed and a 24h exogenous corticosterone rhythm at physiological levels was reestablished by use of a programmable infusion pump. Results: Daily rhythms were detected for Per1, Per2, Bmal1, Nr1d1, and Dbp, while clock gene products were confirmed in both the hippocampus proper and the dentate gyrus. In sham controls, differential hippocampal expression of Per1 and Dbp between ZT3 and ZT15 was detectable. This rhythm was abolished by SCN-lesion; however, reestablishing the natural rhythm in corticosterone restored differential rhythmic expression of both Per1 and Dbp. Further, a 6h phase-delay in the corticosterone profile caused a predictable shift in expression of Nr1d1. Conclusion: Our data show that rhythmic corticosterone can drive hippocampal clock gene rhythms suggesting that the SCN regulates the circadian oscillator of the hippocampus by controlling the circadian rhythm in circulating glucocorticoids.
DOI: 10.6084/m9.figshare.23804019.v1
title: Supplementary Material for: Circadian clock genes are regulated by rhythmic corticosterone at physiological levels in the rat hippocampus

description: Introduction: In the hippocampus, clock gene expression is important for memory and mood; however, the signaling mechanism controlling clock gene expression in the hippocampus is unknown. Recent findings suggest that circadian glucocorticoid rhythms driven by the suprachiasmatic nucleus (SCN) control rhythmic clock gene expression in neurons; in addition, dexamethasone modulates hippocampal clock gene expression. We therefore hypothesized that oscillations of clock genes in the hippocampus could be driven by SCN-controlled circadian rhythms in glucocorticoids. Methods: Temporal profiles of hippocampal clock gene expression were established by qRT-PCR on rat hippocampi, while cellular distribution was established by in situ hybridization. To determine the effect of rhythmic glucocorticoids on hippocampal clock gene expression, the SCN was lesioned, adrenal glands removed and a 24h exogenous corticosterone rhythm at physiological levels was reestablished by use of a programmable infusion pump. Results: Daily rhythms were detected for Per1, Per2, Bmal1, Nr1d1, and Dbp, while clock gene products were confirmed in both the hippocampus proper and the dentate gyrus. In sham controls, differential hippocampal expression of Per1 and Dbp between ZT3 and ZT15 was detectable. This rhythm was abolished by SCN-lesion; however, reestablishing the natural rhythm in corticosterone restored differential rhythmic expression of both Per1 and Dbp. Further, a 6h phase-delay in the corticosterone profile caused a predictable shift in expression of Nr1d1. Conclusion: Our data show that rhythmic corticosterone can drive hippocampal clock gene rhythms suggesting that the SCN regulates the circadian oscillator of the hippocampus by controlling the circadian rhythm in circulating glucocorticoids.
DOI: 10.5281/zenodo.8116664
title: Cipher Machine Hagelin CX-52 (Inv. 1987-180)

description: This dataset represents the computed tomography image acquisition of a historical cipher machine from the collection of the Deutsches Museum. It is composed of CT reconstructed image stacks in the DICOM (.dcm) format.<br> It can be imported in any free or propietary CT-Viewer that supports the DICOM standard to generated 2D and 3D imaging.<br> If segmentations/ROIs are availabe, they are uploaded in a seperate image stacks and are a subset of the scanned cipher machine.<br> <br> object details:<br> name: Hagelin CX-52<br> Inv.-No. of the Deutsches Museum: 1987-180 file object details:<br> file format: image/dcm<br> pixel spacing unit: mm<br> X pixel spacing: 0.154<br> Y pixel spacing: 0.154<br> Z pixel spacing: 0.154<br> grid size x: 1685<br> grid size y: 1002<br> grid size z: 701<br> color depth: 16Bit ownership & image acquisition:<br> project: 3D-Cipher<br> collection: Deutsches Museum<br> IP holder: Deutsches Museum<br> license: Creative Commons BY-SA 4.0<br> scanning facility: Fraunhofer Development Center X-ray Technology EZRT/Fraunhofer IIS<br> scanning device: High Energy CT XXL-CT<br> Funding attribution: German Federal Ministry of Education and Research<br> acknowledgement: CryptoMuseum (as main source for informations about the cipher machines)
description: Funding: German Federal Ministry of Education and Research (BMBF), grant programme: eHeritage.
DOI: 10.5281/zenodo.8116665
title: Cipher Machine Hagelin CX-52 (Inv. 1987-180)

description: This dataset represents the computed tomography image acquisition of a historical cipher machine from the collection of the Deutsches Museum. It is composed of CT reconstructed image stacks in the DICOM (.dcm) format.<br> It can be imported in any free or propietary CT-Viewer that supports the DICOM standard to generated 2D and 3D imaging.<br> If segmentations/ROIs are availabe, they are uploaded in a seperate image stacks and are a subset of the scanned cipher machine.<br> <br> object details:<br> name: Hagelin CX-52<br> Inv.-No. of the Deutsches Museum: 1987-180 file object details:<br> file format: image/dcm<br> pixel spacing unit: mm<br> X pixel spacing: 0.154<br> Y pixel spacing: 0.154<br> Z pixel spacing: 0.154<br> grid size x: 1685<br> grid size y: 1002<br> grid size z: 701<br> color depth: 16Bit ownership & image acquisition:<br> project: 3D-Cipher<br> collection: Deutsches Museum<br> IP holder: Deutsches Museum<br> license: Creative Commons BY-SA 4.0<br> scanning facility: Fraunhofer Development Center X-ray Technology EZRT/Fraunhofer IIS<br> scanning device: High Energy CT XXL-CT<br> Funding attribution: German Federal Ministry of Education and Research<br> acknowledgement: CryptoMuseum (as main source for informations about the cipher machines)
description: Funding: German Federal Ministry of Education and Research (BMBF), grant programme: eHeritage.
DOI: 10.34740/kaggle/dsv/5207872
title: Pesplanus Dataset
DOI: 10.34740/kaggle/dsv/6451822
title: Global Genomic Neurofibromatosis Neoplasia
DOI: 10.6084/m9.figshare.23909547.v1
title: Supplementary Material for: The impact of thrombocytopenia and lymphopenia on mortality in patients infected with Influenza virus – a retrospective cohort study

description: Introduction Influenza virus causes significant global annual morbidity and mortality. Thrombocytopenia is recognized as a poor prognostic factor in sepsis and is associated with mortality, while lymphopenia has been established as a poor prognostic factor in other viral infections. We aimed to assess the incidence of thrombocytopenia and lymphopenia in seasonal influenza and their effect on clinical outcomes. Methods This single-center, retrospective, cohort study included consecutive adult patients, hospitalized in Rabin Medical Center between October 2017 - April 2018, with laboratory confirmed influenza. Patients were grouped according to blood counts on admission: 1. Thrombocytopenia (&lt;150 K/ml), 2. lymphopenia (&lt;0.5K/ml), and 3. both thrombocytopenia and lymphopenia. Patients without thrombocytopenia and lymphopenia were designated as controls. The primary outcome was 30-days all-cause mortality. Risk factors were identified by univariable and multivariable analyses, using logistic regression and reported as odds ratios (OR) and 95% confidence intervals (CI). Results A total of 625 patients were included, 112 (18%) had thrombocytopenia, 98 (15.6%) had lymphopenia and 107 (17%) had both. The crude 30-days all-cause mortality was 7.6% (48/625). Mortality rates were 7.1% (8/112) for the thrombocytopenia group, 11.2% (11/98) for the lymphopenia group, and 14.9% (16/107) for patients with both vs 4.2% (13/308) in the control (p=0.000 for all). In a multivariable regression model, significant thrombocytopenia (&lt;100 K/microL) [OR 5.07, (95% CI 1.5-16.2)[, age [OR 1.07, (95% CI 1.02-1.11)], time to oseltamivir ]OR 1.006, (95%1.002-1.11)], and significant respiratory support [OR 8.85, (3.4-22.6)], were associated with 30-day all-cause mortality. Conclusion Patients hospitalized with seasonal influenza and thrombocytopenia &lt; 100K/mL on admission, have an increased 30-days all-cause mortality.
DOI: 10.6084/m9.figshare.23925117.v1
title: Supplementary Material for: Childhood-onset Refractory Hypertension Results from Neurofibromatosis type 1 Caused by a Splicing NF1 mutation

description: Background: Neurofibromatosis type 1 (NF-1) is caused by mutations in the NF1 gene that encodes neurofibromin, a negative regulator of RAS proto-oncogene. Approximately one-third of the reported pathogenic mutations in NF1 are splicing mutations, but most consequences are unclear. The objective of this study was to identify the pathogenicity of splicing mutation in a Chinese family with NF-1 and determine the effects of the pre-mRNA splicing mutation by in vitro functional analysis. Methods: Next-generation sequencing was used to screen candidate mutations. We performed a minigene splicing assay to determine the effect of the splicing mutation on NF1 expression and three-dimensional structure models of neurofibromin were generated using SWISS-MODEL and PROCHECK method, respectively. Results: A pathogenic splicing mutation c.479+1G&gt;C in NF1 was found in the proband characterized by childhood-onset refractory hypertension. In vitro analysis demonstrated that c.479+1G&gt;C mutation caused skipping of exon 4, leading to a Glutamine to Valine substitution at position 97 in neurofibromin and an open reading frame shift terminating at codon 108. Protein modelling showed that several major domains were missing in the truncated neurofibromin protein. Conclusion: The splicing mutation c.479+1G&gt;C identified in a Chinese patient with NF-1 and childhood-onset refractory hypertension caused skipping of exon 4 and a truncated protein. Our findings offered new evidence for the molecular diagnosis of NF-1.