cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.6168290.v1
title: Additional file 1: of Analysis of hepatic transcriptome demonstrates altered lipid metabolism following Lactobacillus johnsonii BS15 prevention in chickens with subclinical necrotic enteritis

description: Table S1. Details for regulatory genes and pathways related to lipid metabolism in comparison of control group and SNE group. (XLSX 120 kb)
DOI: 10.6084/m9.figshare.6168311
title: Additional file 2: of Analysis of hepatic transcriptome demonstrates altered lipid metabolism following Lactobacillus johnsonii BS15 prevention in chickens with subclinical necrotic enteritis

description: Table S2. Details for genes and pathways relevant to lipid metabolism mediating the preventive effects of BS15 treatment bases on SNE chickens. (XLSX 13 kb)
DOI: 10.6084/m9.figshare.6168311.v1
title: Additional file 2: of Analysis of hepatic transcriptome demonstrates altered lipid metabolism following Lactobacillus johnsonii BS15 prevention in chickens with subclinical necrotic enteritis

description: Table S2. Details for genes and pathways relevant to lipid metabolism mediating the preventive effects of BS15 treatment bases on SNE chickens. (XLSX 13 kb)
DOI: 10.6084/m9.figshare.6168326
title: Additional file 3: of Analysis of hepatic transcriptome demonstrates altered lipid metabolism following Lactobacillus johnsonii BS15 prevention in chickens with subclinical necrotic enteritis

description: Table S3. Details for regulatory genes and pathways related to lipid metabolism in comparison of control group and BS15 group. (XLSX 42 kb)
DOI: 10.6084/m9.figshare.6168326.v1
title: Additional file 3: of Analysis of hepatic transcriptome demonstrates altered lipid metabolism following Lactobacillus johnsonii BS15 prevention in chickens with subclinical necrotic enteritis

description: Table S3. Details for regulatory genes and pathways related to lipid metabolism in comparison of control group and BS15 group. (XLSX 42 kb)
DOI: 10.6084/m9.figshare.6169034
title: MOESM10 of The role of retinoic acid signaling in starfish metamorphosis

description: Additional file 10: Supplementary dataset 1. The dataset for phylogenetic analysis of Raldh and Aldh2.
DOI: 10.6084/m9.figshare.6169034.v1
title: MOESM10 of The role of retinoic acid signaling in starfish metamorphosis

description: Additional file 10: Supplementary dataset 1. The dataset for phylogenetic analysis of Raldh and Aldh2.
DOI: 10.6084/m9.figshare.6169043
title: MOESM11 of The role of retinoic acid signaling in starfish metamorphosis

description: Additional file 11: Supplementary dataset 2. The dataset for phylogenetic analysis of RAR, RXR and THR.
DOI: 10.6084/m9.figshare.6169043.v1
title: MOESM11 of The role of retinoic acid signaling in starfish metamorphosis

description: Additional file 11: Supplementary dataset 2. The dataset for phylogenetic analysis of RAR, RXR and THR.
DOI: 10.6084/m9.figshare.6169427
title: Imaging CF3I conical intersection and photodissociation dynamics by ultrafast electron diffraction

description: Data from both ultrafast electron diffraction experiment and full multiple spawn simulation for CF3I molecule pumped by femtosecond UV laser. <br><br>
DOI: 10.6084/m9.figshare.6169427.v1
title: Imaging CF3I conical intersection and photodissociation dynamics by ultrafast electron diffraction

description: Data from both ultrafast electron diffraction experiment and full multiple spawn simulation for CF3I molecule pumped by femtosecond UV laser. <br><br>
DOI: 10.6084/m9.figshare.6174971
title: Additional file 10: of Effects of drought stress and water recovery on physiological responses and gene expression in maize seedlings

description: Numbers of DEGs in different metabolisms in response to water deficit and recovery. (XLSX 9Â kb)
DOI: 10.6084/m9.figshare.6174971.v1
title: Additional file 10: of Effects of drought stress and water recovery on physiological responses and gene expression in maize seedlings

description: Numbers of DEGs in different metabolisms in response to water deficit and recovery. (XLSX 9Â kb)
DOI: 10.6084/m9.figshare.6175037
title: Additional file 3: of Effects of drought stress and water recovery on physiological responses and gene expression in maize seedlings

description: Summary of reads, mapped to B73 reference genome, yielded by illumina sequencing technique. (XLSX 9Â kb)
DOI: 10.6084/m9.figshare.6175037.v1
title: Additional file 3: of Effects of drought stress and water recovery on physiological responses and gene expression in maize seedlings

description: Summary of reads, mapped to B73 reference genome, yielded by illumina sequencing technique. (XLSX 9Â kb)
DOI: 10.6084/m9.figshare.6175049
title: Additional file 4: of Effects of drought stress and water recovery on physiological responses and gene expression in maize seedlings

description: Up regulated genes at 3Â day, 6Â day and re-watered stages. (XLSX 194Â kb)
DOI: 10.6084/m9.figshare.6175049.v1
title: Additional file 4: of Effects of drought stress and water recovery on physiological responses and gene expression in maize seedlings

description: Up regulated genes at 3Â day, 6Â day and re-watered stages. (XLSX 194Â kb)
DOI: 10.6084/m9.figshare.6175067
title: Additional file 5: of Effects of drought stress and water recovery on physiological responses and gene expression in maize seedlings

description: Down regulated genes at 3Â day, 6Â day and re-watered stages. (XLSX 268Â kb)
DOI: 10.6084/m9.figshare.6175067.v1
title: Additional file 5: of Effects of drought stress and water recovery on physiological responses and gene expression in maize seedlings

description: Down regulated genes at 3Â day, 6Â day and re-watered stages. (XLSX 268Â kb)
DOI: 10.6084/m9.figshare.6175085
title: Additional file 6: of Effects of drought stress and water recovery on physiological responses and gene expression in maize seedlings

description: The overlap DEGs between maize seedlings and silk, ovary tissues. (XLSX 20Â kb)
DOI: 10.6084/m9.figshare.6175085.v1
title: Additional file 6: of Effects of drought stress and water recovery on physiological responses and gene expression in maize seedlings

description: The overlap DEGs between maize seedlings and silk, ovary tissues. (XLSX 20Â kb)
DOI: 10.6084/m9.figshare.6175106
title: Additional file 7: of Effects of drought stress and water recovery on physiological responses and gene expression in maize seedlings

description: Up regulated TFs at 3Â day, 6Â day and re-watered stages. (XLSX 24Â kb)
DOI: 10.6084/m9.figshare.6175106.v1
title: Additional file 7: of Effects of drought stress and water recovery on physiological responses and gene expression in maize seedlings

description: Up regulated TFs at 3Â day, 6Â day and re-watered stages. (XLSX 24Â kb)
DOI: 10.6084/m9.figshare.6175118
title: Additional file 8: of Effects of drought stress and water recovery on physiological responses and gene expression in maize seedlings

description: Down regulated TFs at 3Â day, 6Â day and re-watered stages. (XLSX 23Â kb)
DOI: 10.6084/m9.figshare.6175118.v1
title: Additional file 8: of Effects of drought stress and water recovery on physiological responses and gene expression in maize seedlings

description: Down regulated TFs at 3Â day, 6Â day and re-watered stages. (XLSX 23Â kb)
DOI: 10.6084/m9.figshare.6175133
title: Additional file 9: of Effects of drought stress and water recovery on physiological responses and gene expression in maize seedlings

description: Enriched GO terms among the DEGs in response to water deficit and recovery. (XLSX 20Â kb)
DOI: 10.6084/m9.figshare.6175133.v1
title: Additional file 9: of Effects of drought stress and water recovery on physiological responses and gene expression in maize seedlings

description: Enriched GO terms among the DEGs in response to water deficit and recovery. (XLSX 20Â kb)
DOI: 10.6084/m9.figshare.6175148
title: Additional file 1: of First case of AML with rare chromosome translocations: a case report of twins

description: Fusion Report. (XLS 2Â kb)
DOI: 10.6084/m9.figshare.6175148.v1
title: Additional file 1: of First case of AML with rare chromosome translocations: a case report of twins

description: Fusion Report. (XLS 2Â kb)
DOI: 10.6084/m9.figshare.6175433
title: Additional file 1: of Pretreatment microRNA levels can predict HBsAg clearance in CHB patients treated with pegylated interferon Îą-2a

description: Predicted target genes of miRNAs (XLSX 37Â kb)
DOI: 10.6084/m9.figshare.6175433.v1
title: Additional file 1: of Pretreatment microRNA levels can predict HBsAg clearance in CHB patients treated with pegylated interferon Îą-2a

description: Predicted target genes of miRNAs (XLSX 37Â kb)
DOI: 10.6084/m9.figshare.6175505
title: Additional file 4: of Pretreatment microRNA levels can predict HBsAg clearance in CHB patients treated with pegylated interferon Îą-2a

description: The biological pathways of the differential expressed miRNAs target genes (XLSX 24Â kb)
DOI: 10.6084/m9.figshare.6175505.v1
title: Additional file 4: of Pretreatment microRNA levels can predict HBsAg clearance in CHB patients treated with pegylated interferon Îą-2a

description: The biological pathways of the differential expressed miRNAs target genes (XLSX 24Â kb)
DOI: 10.6084/m9.figshare.6179318
title: Efficacy of targeted therapy for advanced renal cell carcinoma: A systematic review and meta-analysis of randomized controlled trials

description: ABSTRACT We conducted a systematic review and meta-analysis of the literature on the efficacy of the targeted therapies in the treatment of advanced RCC and, via an indirect comparison, to provide an optimal treatment among these agents. A systematic search of Medline, Scopus, Cochrane Library and Clinical Trials unpublished was performed up to Jan 1, 2015 to identify eligible randomized trials. Outcomes of interest assessing a targeted agent included progression free survival (PFS), overall survival (OS) and objective response rate (ORR). Thirty eligible randomized controlled studies, total twentyfourth trails (5110 cases and 4626 controls) were identified. Compared with placebo and IFN-α, single vascular epithelial growth factor (receptor) tyrosine kinase inhibitor and mammalian target of rapamycin agent (VEGF(r)-TKI & mTOR inhibitor) were associated with improved PFS, improved OS and higher ORR, respectively. Comparing sorafenib combination vs sorafenib, there was no significant difference with regard to PFS and OS, but with a higher ORR. Comparing single or combination VEGF(r)-TKI & mTOR inhibitor vs BEV + IFN-α, there was no significant difference with regard to PFS, OS, or ORR. Our network ITC meta-analysis also indicated a superior PFS of axitinib and everolimus compared to sorafenib. Our data suggest that targeted therapy with VEGF(r)-TKI & mTOR inhibitor is associated with superior efficacy for treating advanced RCC with improved PFS, OS and higher ORR compared to placebo and IFN-α. In summary, here we give a comprehensive overview of current targeted therapies of advanced RCC that may provide evidence for the adequate targeted therapy selecting.
DOI: 10.6084/m9.figshare.6179318.v1
title: Efficacy of targeted therapy for advanced renal cell carcinoma: A systematic review and meta-analysis of randomized controlled trials

description: ABSTRACT We conducted a systematic review and meta-analysis of the literature on the efficacy of the targeted therapies in the treatment of advanced RCC and, via an indirect comparison, to provide an optimal treatment among these agents. A systematic search of Medline, Scopus, Cochrane Library and Clinical Trials unpublished was performed up to Jan 1, 2015 to identify eligible randomized trials. Outcomes of interest assessing a targeted agent included progression free survival (PFS), overall survival (OS) and objective response rate (ORR). Thirty eligible randomized controlled studies, total twentyfourth trails (5110 cases and 4626 controls) were identified. Compared with placebo and IFN-α, single vascular epithelial growth factor (receptor) tyrosine kinase inhibitor and mammalian target of rapamycin agent (VEGF(r)-TKI & mTOR inhibitor) were associated with improved PFS, improved OS and higher ORR, respectively. Comparing sorafenib combination vs sorafenib, there was no significant difference with regard to PFS and OS, but with a higher ORR. Comparing single or combination VEGF(r)-TKI & mTOR inhibitor vs BEV + IFN-α, there was no significant difference with regard to PFS, OS, or ORR. Our network ITC meta-analysis also indicated a superior PFS of axitinib and everolimus compared to sorafenib. Our data suggest that targeted therapy with VEGF(r)-TKI & mTOR inhibitor is associated with superior efficacy for treating advanced RCC with improved PFS, OS and higher ORR compared to placebo and IFN-α. In summary, here we give a comprehensive overview of current targeted therapies of advanced RCC that may provide evidence for the adequate targeted therapy selecting.
DOI: 10.6084/m9.figshare.6179375
title: Acetic acid production by the newly isolated Pseudomonas sp. CSJ-3

description: ABSTRACT A fermentative acetic acid producing strain, named CSJ-3, was isolated from sludge and identified as Pseudomonas sp. on the basis of 16S rRNA gene analysis. The effects of cultivation conditions on the production of acetic acid by Pseudomonas sp. CSJ-3 were investigated in batch fermentation, and the maximum yield of acetic acid reached up to 0.49 % during 30 h cultivation under the optimum growth condition, including fermentation temperature of 37.0 ºC, fermentation pH of 4.50, ethanol concentration of 8 %, carbon source (glucose) amount of 10 g/L, and rotation speed of 120 r/min. When ultraviolet (UV) irradiation was used for the mutation in culture medium to improve the yield of acetic acid, the results showed that the yield of acetic acid reached up to 0.59 %. UV and FTIR confirmed that acetic acid was the major fermented product.
DOI: 10.6084/m9.figshare.6179375.v1
title: Acetic acid production by the newly isolated Pseudomonas sp. CSJ-3

description: ABSTRACT A fermentative acetic acid producing strain, named CSJ-3, was isolated from sludge and identified as Pseudomonas sp. on the basis of 16S rRNA gene analysis. The effects of cultivation conditions on the production of acetic acid by Pseudomonas sp. CSJ-3 were investigated in batch fermentation, and the maximum yield of acetic acid reached up to 0.49 % during 30 h cultivation under the optimum growth condition, including fermentation temperature of 37.0 ºC, fermentation pH of 4.50, ethanol concentration of 8 %, carbon source (glucose) amount of 10 g/L, and rotation speed of 120 r/min. When ultraviolet (UV) irradiation was used for the mutation in culture medium to improve the yield of acetic acid, the results showed that the yield of acetic acid reached up to 0.59 %. UV and FTIR confirmed that acetic acid was the major fermented product.
DOI: 10.6084/m9.figshare.6179402
title: Prostate cancer incidentally discovered at the time of radical cystoprostatectomy does not decrease overall survival: Results from a large Chinese medical center

description: ABSTRACT Purpose To investigate the incidence and pathologic characteristics of prostate cancer (PCa) incidentally discovered at the time of radical cystectomy and its impact on overall survival. Materials and Methods A single center retrospective study of 762 male patients who underwent radical cystoprostatectomy from Jan 1994 to Dec 2012. Results Of all included patients, 132 (17.3%) were found to have PCa. Patients with incidental PCa had a significantly higher mean age (69.2 vs. 62.2 years, P=0.015). Among the 132 patients with PCa, prostate specific antigen (PSA) analysis was available in 76 patients (57.6%), with a median value of 1.06ng/mL, and 61 (80.3%) patients had a PSA value below 4ng/mL. Four hundred and thirty-six patients (57.1%) were successfully followed, with a median duration of 46.5 months. The overall 5-year survival rate was 62.1%, and the 5-year cancer–specific survival rate was 72%. PCa recurrence was defined by two consecutive PSA values of &gt;0.2 ng/mL and rising, and no PCa recurrence occurred. According to a univariate analyses, incidental PCa was not associated with cancer-specific survival (P=0.192) or overall survival (P=0.493). According to univariate analyses, the overall survival of patients with PCa was not associated with prostate cancer staging, PSA value, or Gleason score (All P values&gt;0.05). Conclusions Prostate cancer incidentally discovered at the time of radical cystectomy does not decrease overall survival. Patients with incidental PCa were older than those without. The PSA value before operation is not helpful for predicting incidental prostate cancers.
DOI: 10.6084/m9.figshare.6179402.v1
title: Prostate cancer incidentally discovered at the time of radical cystoprostatectomy does not decrease overall survival: Results from a large Chinese medical center

description: ABSTRACT Purpose To investigate the incidence and pathologic characteristics of prostate cancer (PCa) incidentally discovered at the time of radical cystectomy and its impact on overall survival. Materials and Methods A single center retrospective study of 762 male patients who underwent radical cystoprostatectomy from Jan 1994 to Dec 2012. Results Of all included patients, 132 (17.3%) were found to have PCa. Patients with incidental PCa had a significantly higher mean age (69.2 vs. 62.2 years, P=0.015). Among the 132 patients with PCa, prostate specific antigen (PSA) analysis was available in 76 patients (57.6%), with a median value of 1.06ng/mL, and 61 (80.3%) patients had a PSA value below 4ng/mL. Four hundred and thirty-six patients (57.1%) were successfully followed, with a median duration of 46.5 months. The overall 5-year survival rate was 62.1%, and the 5-year cancer–specific survival rate was 72%. PCa recurrence was defined by two consecutive PSA values of &gt;0.2 ng/mL and rising, and no PCa recurrence occurred. According to a univariate analyses, incidental PCa was not associated with cancer-specific survival (P=0.192) or overall survival (P=0.493). According to univariate analyses, the overall survival of patients with PCa was not associated with prostate cancer staging, PSA value, or Gleason score (All P values&gt;0.05). Conclusions Prostate cancer incidentally discovered at the time of radical cystectomy does not decrease overall survival. Patients with incidental PCa were older than those without. The PSA value before operation is not helpful for predicting incidental prostate cancers.
DOI: 10.6084/m9.figshare.6179504
title: Subclinical Anthracycline-Induced Cardiotoxicity in the Long - Term Follow-Up of Lymphoma Survivors: A Multi-Layer Speckle Tracking Analysis

description: Abstract Background: Anthracycline generates progressive left ventricular dysfunction associated with a poor prognosis. Objectives: The purpose of this study was to evaluate whether layer-specific strain analysis could assess the subclinical left ventricular dysfunction after exposure to anthracycline. Methods: Forty-two anthracycline-treated survivors of large B-cell non-Hodgkin lymphoma, aged 55.83 ± 17.92 years (chemotherapy group) and 27 healthy volunteers, aged 51.39 ± 13.40 years (control group) were enrolled. The cumulative dose of epirubicin in chemotherapy group was 319.67 ± 71.71mg/m2. The time from last dose of epirubicin to the echocardiographic examination was 52.92 ± 22.32 months. Global longitudinal (GLS), circumferential (GCS) and radial strain (GRS), subendocardial, mid and subepicardial layer of longitudinal (LS-ENDO, LS-MID, LS-EPI) and circumferential strain (CS-ENDO, CS-MID, CS-EPI) values were analyzed. Transmural strain gradient was calculated as differences in peak systolic strain between the subendocardial and subepicardial layers. A value of p &lt; 0.05 was considered significant. Results: Conventional parameters of systolic and diastolic function showed no significant difference between two groups. Compared with controls, patients had significantly lower GCS and GLS. Multi-layer speckle tracking analysis showed significant reduction of circumferential strain of subendocardial layer, transmural CS gradient and longitudinal strain of all three layers. In contrast, the two groups did not differ in transmural longitudinal strain gradient and radial strains. Conclusions: It proved the preferential impairment of subendocardial deformation in long-term survivors after exposure to anthracycline. Multi-layer speckle tracking echocardiography might facilitate the longitudinal follow-up of this at-risk patient cohort.
DOI: 10.6084/m9.figshare.6179504.v1
title: Subclinical Anthracycline-Induced Cardiotoxicity in the Long - Term Follow-Up of Lymphoma Survivors: A Multi-Layer Speckle Tracking Analysis

description: Abstract Background: Anthracycline generates progressive left ventricular dysfunction associated with a poor prognosis. Objectives: The purpose of this study was to evaluate whether layer-specific strain analysis could assess the subclinical left ventricular dysfunction after exposure to anthracycline. Methods: Forty-two anthracycline-treated survivors of large B-cell non-Hodgkin lymphoma, aged 55.83 ± 17.92 years (chemotherapy group) and 27 healthy volunteers, aged 51.39 ± 13.40 years (control group) were enrolled. The cumulative dose of epirubicin in chemotherapy group was 319.67 ± 71.71mg/m2. The time from last dose of epirubicin to the echocardiographic examination was 52.92 ± 22.32 months. Global longitudinal (GLS), circumferential (GCS) and radial strain (GRS), subendocardial, mid and subepicardial layer of longitudinal (LS-ENDO, LS-MID, LS-EPI) and circumferential strain (CS-ENDO, CS-MID, CS-EPI) values were analyzed. Transmural strain gradient was calculated as differences in peak systolic strain between the subendocardial and subepicardial layers. A value of p &lt; 0.05 was considered significant. Results: Conventional parameters of systolic and diastolic function showed no significant difference between two groups. Compared with controls, patients had significantly lower GCS and GLS. Multi-layer speckle tracking analysis showed significant reduction of circumferential strain of subendocardial layer, transmural CS gradient and longitudinal strain of all three layers. In contrast, the two groups did not differ in transmural longitudinal strain gradient and radial strains. Conclusions: It proved the preferential impairment of subendocardial deformation in long-term survivors after exposure to anthracycline. Multi-layer speckle tracking echocardiography might facilitate the longitudinal follow-up of this at-risk patient cohort.
DOI: 10.6084/m9.figshare.6179507
title: Competitive Adsorption of Dye Species onto Biomass Nanoporous Carbon in Single and Bicomponent Systems

description: ABSTRACT We first present a cost-effective approach to simultaneously dispose of rutaceae plant waste (the discarded peels of orange, finger citron, pomelo and lemon) to yield biomass nanoporous carbons (BNCs). The adsorption of orange II (OII) and acid chrome blue K (ACBK) from aqueous solutions in single and binary dye systems by four types of BNCs were studied in a batch adsorption system. The adsorption studies include both equilibrium adsorption isotherms and kinetics. Four adsorption models for predicting the multicomponent equilibrium sorption isotherms have been compared in order to determine which one is the best fit model to predict or correlate binary adsorption data. The kinetic data were well described by the pseudo-second-order kinetic model. It was found that the adsorption capacity of orange peel-based nanoporous carbon (OPC) is much higher than those of the other types of BNCs. In addition, OPC also shows higher OII uptake capacities from binary dye solutions. The four types of BNCs could be employed as a low-cost alternative for the removal of textile dyes from effluents.