cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.24126156
title: Supplementary Material for: Assessing the Acceptability of Less Invasive Caries Removal Techniques for treating Deep Carious Lesions: A Conjoint Survey among Dentists Practicing in a Midwestern American State”

description: Background: This study identified factors that influence dentists’ decisions regarding less invasive caries removal techniques such as stepwise removal (SW) and selective removal (SE) using a marketing research technique, conjoint analysis. Methods: A survey was sent to 1,434 dentists practicing in Iowa. Dentists were randomly assigned to receive a questionnaire to rate the likelihood they would use either SW/SE in hypothetical clinical scenarios. The scenarios were carefully created by conjoint design and included three relevant attributes: depth of lesion, hardness of carious dentin and patient age. Descriptive and conjoint analysis were performed to assess trade-offs between these attributes, using SPSS Results: The study revealed that depth of lesion was the most important factor in dentists’ decisions (49 importance value) when choosing a SW to treat a deep carious lesion (DCL), followed by hardness of carious dentin and patient age (21 importance value). For the SE-group, depth of the lesion was also the predominant factor when selecting a treatment. The study also identified that a high proportion of dentists (24.9%) indicated they would never consider using SW or SE under any circumstances. Conclusions: Our survey showed that depth of lesion was the most important reason to select a less invasive caries removal method. The high proportion of dentists indicating they would never consider selective caries removal techniques suggests that these less invasive options are underutilized.
DOI: 10.6084/m9.figshare.24126156.v11
title: Supplementary Material for: Assessing the Acceptability of Less Invasive Caries Removal Techniques for treating Deep Carious Lesions: A Conjoint Survey among Dentists Practicing in a Midwestern American State”

description: Background: This study identified factors that influence dentists’ decisions regarding less invasive caries removal techniques such as stepwise removal (SW) and selective removal (SE) using a marketing research technique, conjoint analysis. Methods: A survey was sent to 1,434 dentists practicing in Iowa. Dentists were randomly assigned to receive a questionnaire to rate the likelihood they would use either SW/SE in hypothetical clinical scenarios. The scenarios were carefully created by conjoint design and included three relevant attributes: depth of lesion, hardness of carious dentin and patient age. Descriptive and conjoint analysis were performed to assess trade-offs between these attributes, using SPSS Results: The study revealed that depth of lesion was the most important factor in dentists’ decisions (49 importance value) when choosing a SW to treat a deep carious lesion (DCL), followed by hardness of carious dentin and patient age (21 importance value). For the SE-group, depth of the lesion was also the predominant factor when selecting a treatment. The study also identified that a high proportion of dentists (24.9%) indicated they would never consider using SW or SE under any circumstances. Conclusions: Our survey showed that depth of lesion was the most important reason to select a less invasive caries removal method. The high proportion of dentists indicating they would never consider selective caries removal techniques suggests that these less invasive options are underutilized.
DOI: 10.6084/m9.figshare.24126156.v10
title: Supplementary Material for: Assessing the Acceptability of Less Invasive Caries Removal Techniques for treating Deep Carious Lesions: A Conjoint Survey among Dentists Practicing in a Midwestern American State”

description: Background: This study identified factors that influence dentists’ decisions regarding less invasive caries removal techniques such as stepwise removal (SW) and selective removal (SE) using a marketing research technique, conjoint analysis. Methods: A survey was sent to 1,434 dentists practicing in Iowa. Dentists were randomly assigned to receive a questionnaire to rate the likelihood they would use either SW/SE in hypothetical clinical scenarios. The scenarios were carefully created by conjoint design and included three relevant attributes: depth of lesion, hardness of carious dentin and patient age. Descriptive and conjoint analysis were performed to assess trade-offs between these attributes, using SPSS Results: The study revealed that depth of lesion was the most important factor in dentists’ decisions (49 importance value) when choosing a SW to treat a deep carious lesion (DCL), followed by hardness of carious dentin and patient age (21 importance value). For the SE-group, depth of the lesion was also the predominant factor when selecting a treatment. The study also identified that a high proportion of dentists (24.9%) indicated they would never consider using SW or SE under any circumstances. Conclusions: Our survey showed that depth of lesion was the most important reason to select a less invasive caries removal method. The high proportion of dentists indicating they would never consider selective caries removal techniques suggests that these less invasive options are underutilized.
DOI: 10.5281/zenodo.10406334
title: Data from: International multicenter examination of MOG antibody assays.

description: Raw data set for:


Reindl M, Schanda K, Woodhall M, Tea F, Ramanathan S, Sagen J, Fryer JP, Mills J, Teegen B, Mindorf S, Ritter N, Krummrei U, Stöcker W, Eggert J, Flanagan EP, Ramberger M, Hegen H, Rostasy K, Berger T, Leite MI, Palace J, Irani SR, Dale RC, Probst C, Probst M, Brilot F, Pittock SJ, Waters P. International multicenter examination of MOG antibody assays. Neurol Neuroimmunol Neuroinflamm. 2020 Mar 5;7(2). doi: 10.1212/NXI.0000000000000674. Print 2020 Mar 5. PubMed PMID: 32024795; PubMed Central PMCID: PMC7051197.






 

Objective: To compare the reproducibility of 11 antibody assays for immunoglobulin (Ig) G and IgM myelin oligodendrocyte glycoprotein antibodies (MOG-IgG and MOG-IgM) from 5 international centers.

Methods: The following samples were analyzed: MOG-IgG clearly positive sera (n = 39), MOG-IgG low positive sera (n = 39), borderline negative sera (n = 13), clearly negative sera (n = 40), and healthy blood donors (n = 30). As technical controls, 18 replicates (9 MOG-IgG positive and 9 negative) were included. All samples and controls were recoded, aliquoted, and distributed to the 5 testing centers, which performed the following antibody assays: 5 live and 1 fixed immunofluorescence cell-based assays (CBA-IF, 5 MOG-IgG, and 1 MOG-IgM), 3 live flow cytometry cell-based assays (CBA-FACS, all MOG-IgG), and 2 ELISAs (both MOG-IgG).

Results: We found excellent agreement (96%) between the live CBAs for MOG-IgG for samples previously identified as clearly positive or negative from 4 different national testing centers. The agreement was lower with fixed CBA-IF (90%), and the ELISA showed no concordance with CBAs for detection of human MOG-IgG. All CBAs showed excellent interassay reproducibility. The agreement of MOG-IgG CBAs for borderline negative (77%) and particularly low positive (33%) samples was less good. Finally, most samples from healthy blood donors (97%) were negative for MOG-IgG in all CBAs.

Conclusions: Live MOG-IgG CBAs showed excellent agreement for high positive and negative samples at 3 international testing centers. Low positive samples were more frequently discordant than in a similar comparison of aquaporin-4 antibody assays. Further research is needed to improve international standardization for clinical care.
DOI: 10.5281/zenodo.10406333
title: Data from: International multicenter examination of MOG antibody assays.

description: Raw data set for:


Reindl M, Schanda K, Woodhall M, Tea F, Ramanathan S, Sagen J, Fryer JP, Mills J, Teegen B, Mindorf S, Ritter N, Krummrei U, Stöcker W, Eggert J, Flanagan EP, Ramberger M, Hegen H, Rostasy K, Berger T, Leite MI, Palace J, Irani SR, Dale RC, Probst C, Probst M, Brilot F, Pittock SJ, Waters P. International multicenter examination of MOG antibody assays. Neurol Neuroimmunol Neuroinflamm. 2020 Mar 5;7(2). doi: 10.1212/NXI.0000000000000674. Print 2020 Mar 5. PubMed PMID: 32024795; PubMed Central PMCID: PMC7051197.






 

Objective: To compare the reproducibility of 11 antibody assays for immunoglobulin (Ig) G and IgM myelin oligodendrocyte glycoprotein antibodies (MOG-IgG and MOG-IgM) from 5 international centers.

Methods: The following samples were analyzed: MOG-IgG clearly positive sera (n = 39), MOG-IgG low positive sera (n = 39), borderline negative sera (n = 13), clearly negative sera (n = 40), and healthy blood donors (n = 30). As technical controls, 18 replicates (9 MOG-IgG positive and 9 negative) were included. All samples and controls were recoded, aliquoted, and distributed to the 5 testing centers, which performed the following antibody assays: 5 live and 1 fixed immunofluorescence cell-based assays (CBA-IF, 5 MOG-IgG, and 1 MOG-IgM), 3 live flow cytometry cell-based assays (CBA-FACS, all MOG-IgG), and 2 ELISAs (both MOG-IgG).

Results: We found excellent agreement (96%) between the live CBAs for MOG-IgG for samples previously identified as clearly positive or negative from 4 different national testing centers. The agreement was lower with fixed CBA-IF (90%), and the ELISA showed no concordance with CBAs for detection of human MOG-IgG. All CBAs showed excellent interassay reproducibility. The agreement of MOG-IgG CBAs for borderline negative (77%) and particularly low positive (33%) samples was less good. Finally, most samples from healthy blood donors (97%) were negative for MOG-IgG in all CBAs.

Conclusions: Live MOG-IgG CBAs showed excellent agreement for high positive and negative samples at 3 international testing centers. Low positive samples were more frequently discordant than in a similar comparison of aquaporin-4 antibody assays. Further research is needed to improve international standardization for clinical care.
DOI: 10.6084/m9.figshare.24212682.v1
title: RBFOX2 deregulation promotes pancreatic cancer progression and metastasis through alternative splicing

description: These data contain TIFF and jpeg images of RBFOX2 (RBM9) staining in PDAC TMAs, histology images from mouse models and images from immunocytochemistry confocal images of ABI1 cellular localization in RBFOX2 replete and depleted cells.
DOI: 10.6084/m9.figshare.24212682
title: RBFOX2 deregulation promotes pancreatic cancer progression and metastasis through alternative splicing

description: These data contain TIFF and jpeg images of RBFOX2 (RBM9) staining in PDAC TMAs, histology images from mouse models and images from immunocytochemistry confocal images of ABI1 cellular localization in RBFOX2 replete and depleted cells.
DOI: 10.6084/m9.figshare.24188580.v1
title: Synaptic density affects clinical severity via network dysfunction in syndromes associated with Frontotemporal Lobar Degeneration

description: Data used to derive figures and results in the primary manuscript and in the supplementary materials for Synaptic density affects clinical severity via network dysfunction in syndromes associated with Frontotemporal Lobar Degeneration.
We have also uploaded the Zip folder for the Maybrain software.
DOI: 10.6084/m9.figshare.24188580
title: Synaptic density affects clinical severity via network dysfunction in syndromes associated with Frontotemporal Lobar Degeneration

description: Data used to derive figures and results in the primary manuscript and in the supplementary materials for Synaptic density affects clinical severity via network dysfunction in syndromes associated with Frontotemporal Lobar Degeneration.
We have also uploaded the Zip folder for the Maybrain software.
DOI: 10.6084/m9.figshare.24648513
title: A type VII-secreted lipase toxin with reverse domain arrangement

description: Raw data for figure 5. Microscopy images for S. aureus cells expressing TslA, stained with Sytox Green and Disc3(5). Includes all steps in image analysis.
DOI: 10.25505/fiz.icsd.cc2d05wh
title: CSD 2204716: Experimental Crystal Structure Determination

description: Related Article: Julia-Maria Hübner, Brenna C. Bierman, Reine Wallenberg, Daniel C. Fredrickson|2022|J.Am.Chem.Soc.|144|21016|doi:10.1021/jacs.2c10306
description: An entry from the Inorganic Crystal Structure Database, the world’s repository for inorganic crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the joint CCDC and FIZ Karlsruhe Access Structures service and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.25505/fiz.icsd.cc2d5l5c
title: CSD 2209902: Experimental Crystal Structure Determination

description: Related Article: Daniel B. Straus, Tomasz Klimczuk, Xianghan Xu, Robert J. Cava|2022|Chem.Mater.|34|10772|doi:10.1021/acs.chemmater.2c03051
description: An entry from the Inorganic Crystal Structure Database, the world’s repository for inorganic crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the joint CCDC and FIZ Karlsruhe Access Structures service and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.25505/fiz.icsd.cc2dh0db
title: CSD 2218961: Experimental Crystal Structure Determination

description: Related Article: Bingjie Cai, Danyang Dou, Bingbing Zhang, Ling Li, Ying Wang|2023|Dalton Trans.|52|862|doi:10.1039/D2DT03974E
description: An entry from the Inorganic Crystal Structure Database, the world’s repository for inorganic crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the joint CCDC and FIZ Karlsruhe Access Structures service and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.25505/fiz.icsd.cc2dh0fc
title: CSD 2218962: Experimental Crystal Structure Determination

description: Related Article: Bingjie Cai, Danyang Dou, Bingbing Zhang, Ling Li, Ying Wang|2023|Dalton Trans.|52|862|doi:10.1039/D2DT03974E
description: An entry from the Inorganic Crystal Structure Database, the world’s repository for inorganic crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the joint CCDC and FIZ Karlsruhe Access Structures service and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.6084/m9.figshare.24630672
title: <b>The phylogenetic study on single copy nuclear genes of Sparganium (Typhaceae)</b>

description: 1421 single copy nuclear genes from 29 samples of Sparganium
DOI: 10.6084/m9.figshare.24630672.v1
title: <b>The phylogenetic study on single copy nuclear genes of Sparganium (Typhaceae)</b>

description: 1421 single copy nuclear genes from 29 samples of Sparganium
DOI: 10.34740/kaggle/dsv/7245057
title: AutoXGB
DOI: 10.5281/zenodo.8405498
title: Dataset: Maurel et al. "Hayabusa 2 returned samples reveal a weak to null magnetic field during aqueous alteration of Ryugu's parent body"

description: Samples: C0005 and A0154a from asteroid Ryugu (JAXA Hayabusa 2 mission), CI chondrite Orgueil, CM2 chondrite Daoura 003



C0005: NRM, ARM, IRM demagnetization and anisotropy of ARM (AARM), IRM acquisition

A0154a: NRM demagnetization, AARM

Orgueil: NRM and ARM demagnetization

Daoura 003: NRM demagnetization
DOI: 10.5281/zenodo.8405497
title: Dataset: Maurel et al. "Hayabusa 2 returned samples reveal a weak to null magnetic field during aqueous alteration of Ryugu's parent body"

description: Samples: C0005 and A0154a from asteroid Ryugu (JAXA Hayabusa 2 mission), CI chondrite Orgueil, CM2 chondrite Daoura 003



C0005: NRM, ARM, IRM demagnetization and anisotropy of ARM (AARM), IRM acquisition

A0154a: NRM demagnetization, AARM

Orgueil: NRM and ARM demagnetization

Daoura 003: NRM demagnetization
DOI: 10.6084/m9.figshare.24672117.v1
title: Supplementary Material for: Metformin Regulates the miR-205/VEGFA Axis in Renal Cell Carcinoma Cells – Exploring a Clinical Synergism with Tyrosine Kinase Inhibitors

description: Introduction: Metformin (MF) intake could be associated with a favorable outcome in Sunitinib (SUT)- and Axitinib (AX)-treated clear cell renal cell carcinoma (ccRCC) patients. Functionally, MF induces miR-205, a microRNA serving as a tumor suppressor in several cancers. Methods: qRT-PCR, viability assays and Western blotting analyzed MF and SUT/AX effects in RCC4 and 786-O cells. A tetracycline-inducible overexpression model was used to study the role of miR-205 and its known target gene VEGFA. We analyzed miR-205 and VEGFA within a public and an in-house ccRCC cohort. HUVEC (Human Umbilical Vein Endothelial Cell) sprouting assays examined miR-205 effects on angiogenesis initiation. To determine the influence of the von Hippel-Lindau tumor suppressor (VHL), we examined VHLwt re-expressing RCC4 and 786-O cells. Results: Viability assays confirmed a sensitizing effect of MF towards SUT/AX in RCC4 and 786-O cells. Overexpression of miR-205 diminished VEGFA expression – as did treatment with MF. Tumor tissue displayed a downregulation of miR-205 and an upregulation of VEGFA. Accordingly, miR-205 caused less and shorter vessel sprouts in HUVEC assays. Finally, VHLwt expressing RCC4, and 786-O cells displayed higher miR-205 and lower VEGFA levels. Conclusion: Our results support the protective role of MF in ccRCC and offer functional insights into the clinical synergism with tyrosine kinase inhibitors (TKI).
DOI: 10.6084/m9.figshare.24672117
title: Supplementary Material for: Metformin Regulates the miR-205/VEGFA Axis in Renal Cell Carcinoma Cells – Exploring a Clinical Synergism with Tyrosine Kinase Inhibitors

description: Introduction: Metformin (MF) intake could be associated with a favorable outcome in Sunitinib (SUT)- and Axitinib (AX)-treated clear cell renal cell carcinoma (ccRCC) patients. Functionally, MF induces miR-205, a microRNA serving as a tumor suppressor in several cancers. Methods: qRT-PCR, viability assays and Western blotting analyzed MF and SUT/AX effects in RCC4 and 786-O cells. A tetracycline-inducible overexpression model was used to study the role of miR-205 and its known target gene VEGFA. We analyzed miR-205 and VEGFA within a public and an in-house ccRCC cohort. HUVEC (Human Umbilical Vein Endothelial Cell) sprouting assays examined miR-205 effects on angiogenesis initiation. To determine the influence of the von Hippel-Lindau tumor suppressor (VHL), we examined VHLwt re-expressing RCC4 and 786-O cells. Results: Viability assays confirmed a sensitizing effect of MF towards SUT/AX in RCC4 and 786-O cells. Overexpression of miR-205 diminished VEGFA expression – as did treatment with MF. Tumor tissue displayed a downregulation of miR-205 and an upregulation of VEGFA. Accordingly, miR-205 caused less and shorter vessel sprouts in HUVEC assays. Finally, VHLwt expressing RCC4, and 786-O cells displayed higher miR-205 and lower VEGFA levels. Conclusion: Our results support the protective role of MF in ccRCC and offer functional insights into the clinical synergism with tyrosine kinase inhibitors (TKI).
DOI: 10.25442/hku.24647487
title: Supporting data for "CIM-WV: A 2D semantic segmentation dataset of rich window view contents in high-rise, high-density Hong Kong based on photorealistic City Information Models"

description: This is the official repository of the CIM-WV dataset. For technical details, please refer to:Li, M., Yeh, A. G. & Xue, F. (2023). CIM-WV: A 2D semantic segmentation dataset of rich window view contents in high-rise, high-density Hong Kong based on photorealistic City Information Models. Urban Informatics, 1-24.This study was supported in part by the Department of Science and Technology of Guangdong Province (GDST) (2020B1212030009, 2023A1515010757) and the University of Hong Kong (203720465).<b>Overview of CIM-WV</b>This paper presents a City Information Model (CIM)-generated Window View (CIM-WV) dataset comprising 2,000 annotated images collected in the high-rise, high-density urban areas of Hong Kong. 1) Window view images of CIM-WV depict diversified urban scenes of Hong Kong at different locations, elevations, and orientations2) The CIM-WV includes seven semantic labels, i.e., building, sky, vegetation, road, waterbody, vehicle, and terrain.In addition, we provide variants of DeepLab V3+ models trained on CIM-WV, real window view images, Google Earth CIM-generated window view images from New York, and Google Earth CIM-generated window view images from Singapore, respectively.You can modify the source code here to use the trained DeepLab V3+ models. <b>Contribution</b>1) CIM-WV is the first public CIM-generated photorealistic window view dataset with rich semantics. 2) Comparative analysis shows a more accurate window view assessment using deep learning from CIM-WV than deep transfer learning from ground-level views.3) For urban researchers and practitioners, our publicly accessible deep learning models trained on CIM-WV enable novel multi-source window view-based urban applications including precise real estate valuation, improvement of built environment, and window view-related urban analytics.Please cite our paper and dataset, if you find our work useful for your research and practices. Many thanks.For any inquiries, please feel free to contact Maosu at maosulee@connect.hku.hk or Dr. Frank at xuef@hku.hk.
DOI: 10.25442/hku.24647487.v1
title: Supporting data for "CIM-WV: A 2D semantic segmentation dataset of rich window view contents in high-rise, high-density Hong Kong based on photorealistic City Information Models"

description: This is the official repository of the CIM-WV dataset. For technical details, please refer to:Li, M., Yeh, A. G. & Xue, F. (2023). CIM-WV: A 2D semantic segmentation dataset of rich window view contents in high-rise, high-density Hong Kong based on photorealistic City Information Models. Urban Informatics, 1-24.This study was supported in part by the Department of Science and Technology of Guangdong Province (GDST) (2020B1212030009, 2023A1515010757) and the University of Hong Kong (203720465).<b>Overview of CIM-WV</b>This paper presents a City Information Model (CIM)-generated Window View (CIM-WV) dataset comprising 2,000 annotated images collected in the high-rise, high-density urban areas of Hong Kong. 1) Window view images of CIM-WV depict diversified urban scenes of Hong Kong at different locations, elevations, and orientations2) The CIM-WV includes seven semantic labels, i.e., building, sky, vegetation, road, waterbody, vehicle, and terrain.In addition, we provide variants of DeepLab V3+ models trained on CIM-WV, real window view images, Google Earth CIM-generated window view images from New York, and Google Earth CIM-generated window view images from Singapore, respectively.You can modify the source code here to use the trained DeepLab V3+ models. <b>Contribution</b>1) CIM-WV is the first public CIM-generated photorealistic window view dataset with rich semantics. 2) Comparative analysis shows a more accurate window view assessment using deep learning from CIM-WV than deep transfer learning from ground-level views.3) For urban researchers and practitioners, our publicly accessible deep learning models trained on CIM-WV enable novel multi-source window view-based urban applications including precise real estate valuation, improvement of built environment, and window view-related urban analytics.Please cite our paper and dataset, if you find our work useful for your research and practices. Many thanks.For any inquiries, please feel free to contact Maosu at maosulee@connect.hku.hk or Dr. Frank at xuef@hku.hk.