cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.15022617.v1
title: Supplementary Material for: Glass Ionomer Sealant versus Fluoride Varnish Application to Prevent Occlusal Caries in Primary Second Molars among Preschool Children: A Randomized Controlled Trial

description: Fissure sealant is a recommended preventive measure on permanent molars, but its efficacy on primary molars in preschool children is still in doubt. Sodium fluoride varnish (NaFV) enhances remineralization and is effective in preventing caries in smooth surfaces, but limited information is available regarding its use on occlusal surfaces of primary molars. The present study aimed to compare the efficacy of glass ionomer sealant (GIS) versus topical application of 5% NaFV in preventing and arresting occlusal caries in primary second molars among preschool children. One calibrated examiner examined children aged 3–4 years for visible plaque index (VPI), decayed-missing-filled primary surface (dmfs) index, and extent of carious lesions by the International Caries Detection and Assessment System (ICDAS). Subjects with 1 or more primary second molars that were sound or with incipient lesions (ICDAS 0–1), with distinct visual enamel changes (ICDAS 2), or with localized enamel breakdown (ICDAS 3) were recruited. The children were randomly assigned to either NaFV group – application of 5% NaFV at 3-monthly intervals or GIS group – 1 single placement of GIS. A parental questionnaire was used to collect information on the children’s sociodemographic background and oral health-related habits. Two blinded examiners conducted clinical examinations after 6 and 12 months to evaluate the development of occlusal caries and the retention of GIS. Negative binomial regression using generalized estimating equations was employed to adjust for the clustering effect and evaluate the influence of selected variables on the development of occlusal caries into dentin at 12 months. A total of 323 children with 1,159 primary second molars received the respective preventive measures at baseline. At 12 months, 280 children with 989 molars were evaluated. Caries had developed or progressed into dentin in 7.8% and 8.0% of the molars in the NaFV and GIS groups, respectively, with no significant difference between the groups (<i>p</i> = 0.913). The overall retention rates of GIS were 24.6% and 13.5% at 6 and 12 months, respectively. Regression analyses showed only baseline caries experience, and an ICDAS code had a significant association with occlusal caries progression. Quarterly NaFV application and single GIS placement showed similar effectiveness in the prevention of occlusal caries development among preschool children.
DOI: 10.6084/m9.figshare.25329847.v1
title: Supplementary Material for: Combined genetic association and differed expression analysis of UBE2L3 uncovers a genetic regulatory role of (immuno) proteasome in IgA Nephropathy

description: Introduction: IgA nephropathy (IgAN) is a leading cause of end-stage renal disease. The exact pathogenesis of IgAN is not well defined, but some genetic studies have led to a novel discovery that the (immuno) proteasome probably plays an important role in IgAN.
Methods: We firstly analyzed the association of variants in the UBE2L3 region with susceptibility to IgA nephropathy in 3495 patients and 9101 controls, and then analyzed the association between lead variant and clinical phenotypes in 1803 patients with regular follow-up data. The blood mRNA levels of members of the ubiquitin-proteasome system including UBE2L3 were analyzed in peripheral blood mononuclear cells (PBMCs) from 53 patients and 28 healthy controls. The associations between UBE2L3 and the expression levels of genes involved in Gd-IgA1 production were also explored.
Results: The rs131654 showed the most significant association signal in UBE2L3 region (OR 1.10, 95% CI 1.04-1.16, P = 2.29×10-3), whose genotypes were also associated with the levels of Gd-IgA1 (P = 0.04). The rs131654 was observed to exert cis-eQTL effects on UBE2L3 in various tissues and cell types, particularly in immune-cell types in multiple databases. The UBE2L3, LUBAC, and proteasome subunits were highly expressed in patients compared with healthy controls. High expression levels of UBE2L3 were not only associated with higher proteinuria (r = 0.34, P = 0.01) and lower eGFR (r = -0.28, P = 0.04), also positively correlated with the gene expression of LUBAC and other proteasome subunits. Additionally, mRNA expression levels of UBE2L3 were also positively correlated with IL-6 and RELA, but negatively correlated with the expression levels of the key enzyme in the process of glycosylation including C1GALT1 and C1GALT1C1.
Conclusion: In conclusion, by combined genetic association and differed expression analysis of UBE2L3, our data support a role of genetically conferred dysregulation of the (immuno) proteasome in regulating galactose-deficient IgA1 in the development of IgAN.
DOI: 10.6084/m9.figshare.6002204.v1
title: Statistics of SNP detection and annotation

description: The details of the detected SNPs using SAMtools and subsequent annotation using ANNOVAR are displayed herein, including upstream, exonic, intronic, splicing, downstream, and intergenic SNPs, point mutations, and genome-wide heterozygosity rate.[BH1] [BH1]Must upload, also, to Figshare.
DOI: 10.17632/jpsbf5wx95
title: LINF_110015300

description: Protein of unknown function - conserved; Leishmania infantum (strain JPCM5)
DOI: 10.6084/m9.figshare.12721319.v2
title: ground_motion_flatfile_for_KMA_stations_2003_2019

description: flatfile of the ground-motion data for the stations operated by Korea Meteorological Agency from 2003 to 2019.<br>The paper related to data processing for this flatfile is being reviewed. <br>If someone want to use this data, please contact the author<br>contact : sewoon@hotmail.com
DOI: 10.6084/m9.figshare.19069610.v2
title: Daily precipitation dataset at 0.1° for the Yarlung Zangbo River basin from 2001 to 2015

description: In order to obtain higher precision regional precipitation dataset in the Yarlung Zangbo River basin, two different schemes were proposed on the basis of the two most application potential satellite-based precipitation products, IMERG and CMORPH_BLD. The first method aimed to correct the positive error of IMERG based on high correlation (CC&gt;0.9) between IMERG and gauges. The second algorithm was developed to merge IMERG with CMORPH_BLD by the stepwise linear regression. As the reference, IMERG played a key role in correction of precipitation ratio determination and precipitation event detection. Two daily datasets with 0.1° resolution (BRD_IMERG and IGREA_IMERG-CMORPH) performed better than IMERG in CC, RMSE, ME, FAR and CSI, and streamflow simulation in the whole basin (NS: 0.86 and 0.87; RBIAS: -19% and -11%) and sub-basins. The two proposed methods were relatively simple and efficient for reconstructing higher precision regional precipitation, and the datasets provided a good application demonstration in the alpine region.
DOI: 10.17632/5cg2dmz5nb
title: Supplements for article "COVID-19 and thyroid cancer"

description: Supplementary Figure 1. The boxplots and density diagrams of protein expression distribution in two matrices.
Supplementary Figure 2. The heatmaps of common DEPs in the two expression profiles. (a) COVID-19 compared with not infected, (b) DTC compared with NT.
Note: Euclidean distance and Complete method were used in the clustering. Z-scores were calculated.
Supplementary Figure 3. The bubble chart of (a) gene ontology and (b) pathway enrichment analysis for hub genes. 
Supplement 1. The data for each databases.
DOI: 10.6084/m9.figshare.1224314.v1
title: Highly Cited Documents on Google Scholar (1950-2013)

description: This dataset contains: - A sample of 64,000 highly cited documents published in the period 1950-2013, collected from Google Scholar on the 28th of May, 2014. - List of clean references of the top 1% most cited documents in Google Scholar (640 documents) - Study case: different versions (detected and undetected by Google Scholar) for the work "A Mathematical Theory of Communication", by Claude Shannon.
DOI: 10.6084/m9.figshare.21842130.v1
title: A polygenic basis for birth weight in a wild population of red deer (Cervus elaphus).

description: Individual phenotypic data on birth weight in red deer (<em>Cervus elaphus</em>), and associated genomic data. See ‘Data_description.txt’ for more details. Please contact the authors if you plan to use this data.
DOI: 10.6084/m9.figshare.27880524.v1
title: MHC locus fine-mapping results

description: Results from fine-mapping the MHC locus. Two sets of results are provided (i) before conditioning the MHC region by imputing the HLA alleles, (ii) after conditioning the MHC region imputed with HLA alleles according to the top lead SNP.
DOI: 10.6084/m9.figshare.10052663.v1
title: S1_raw data for behavior analysis.xlsx

description: Raw data for behavior analysis of GluD1 knockout mice with a pure C57BL/6N background.<br>
DOI: 10.6084/m9.figshare.12000753.v1
title: Supplementary Material for: Poststroke Cognitive Impairment in Model-Based Economic Evaluation: A Systematic Review

description: <b><i>Introduction:</i></b> Cognitive impairment (CI) is a frequent consequence of stroke and is associated with increased costs and reduced quality of life. However, its inclusion in model-based economic evaluation for stroke is limited. <b><i>Objective:</i></b> To identify, review, and critically appraise current models of stroke for use in economic evaluation, and to identify applicability to modeling poststroke CI. <b><i>Methods:</i></b> PubMed, EMBASE, and the NHS Economic Evaluations Database (NHS EED) were systematically searched for papers published from January 2008 to August 2018. Studies that described the development or design of a model of stroke progression intended for use in economic evaluation were included. Abstracts were screened, followed by full text review of potentially relevant articles. Models that included CI were retained for data extraction, and among the remainder, models that included both stroke recurrence and disability were also retained. Relevance and potential for adaptation for modeling CI were assessed using a standard questionnaire. <b><i>Results:</i></b> Forty modeling studies were identified and categorized into 4 groups: Markov disability/recurrence (k = 29); CI (k = 2); discrete event simulation (k = 4), and other (k = 5). Only 2 modeling studies included CI as an outcome, and both focused on narrow populations at risk of intracranial aneurysm. None of the models allowed for disease progression in the absence of a stroke recurrence. None of the included studies carried out any sensitivity analysis in relation to model design or structure. <b><i>Conclusions:</i></b> Current stroke models used in economic evaluation are not adequate to model poststroke CI or dementia, and will require adaptation to be used for this purpose.
DOI: 10.6084/m9.figshare.20368390.v1
title: A new podocnemidid (Pleurodira: Pelomedusoides) from the Eocene of north-western Argentina, with comments on its evolutionary relationships and palaeoenvironmental settings

description: We report a new small podocnemidid, <i>Gestemys powelli</i> gen. et sp. nov., based on one nearly complete skull, lower jaw, two shells, and remains of the appendicular skeleton belonging to two specimens from the Eocene Geste Formation of the San Antonio de la Cobres Basin, Salta Province, north-western Argentina. As in other podocnemidid genera, <i>Gestemys</i> exhibits a fully developed and medially extensive cavum pterygoidei, an incisura columellae auris enclosing the stapes and Eustachian tube, and lacks an exoccipital quadrate contact. <i>Gestemys powelli</i> bears a huge foramen palatinum posterius and a short pterygoid flange that does not reach the basisphenoid suture, exposing the cavum pterygoid. Phylogenetic analyses place <i>Gestemys powelli</i> as a member of Podocnemididae more closely related to Erymnochelyinae than Podocnemidinae. In regards to the palaeoenvironmental settings of the Palaeogene formations (Maíz Gordo and Geste) of north-western Argentina, at least two features differentiate the palaeoenvironment where <i>G. powelli</i> was recovered and those of other podocnemidid turtles from the Maíz Gordo Formation: 1) <i>G. powelli</i> was found <i>in situ</i> with very little re-working; and 2) in contrast to the muddy rocks indicating the marginal lacustrine setting and humid climate of the Maíz Gordo Formation, <i>G. powelli</i> is associated with a coarse-grained floodplain setting and a dry, temperate climate. Such differences highlight the contrasting environmental dynamics in which podocnemidid turtles lived during the Palaeogene. http://zoobank.org/urn:lsid:zoobank.org:pub:0E631DA2-053F-4BD6-91BD-2401F34A5777
DOI: 10.17632/rzy2m93jyh
title: Data for: An open-label randomized pragmatic non-inferiority pilot trial comparing the effectiveness of Curare 30cH against individualized homeopathic medicines in post-stroke hemiparesis

description: Post-stroke hemiparesis RCT master chart and Bengali version of the Stroke Impact Scale (SIS) questionnaire
DOI: 10.6084/m9.figshare.16887934.v2
title: Improving cassava bacterial blight resistance by editing the epigenome

description: The zipped folder contains all of the data used in figures for Veley et al. organized by figure number.
DOI: 10.17632/9mw3cnj5ww
title: HIF-Independent Oxygen Sensing Regulates Ferroptosis, by Minikes et al.

description: Raw data for Western blots and images
DOI: 10.6084/m9.figshare.20289099.v2
title: Global Production and Trends in Nighttime Oxidants – Increases in China, Decreases Elsewhere

description: Datasets that support the findings of the study "Global Production and Trends in Nighttime Oxidants – Increases in China, Decreases Elsewhere"
DOI: 10.60893/figshare.apl.26156317.v1
title: Supplementary material

description: Supplementary material
DOI: 10.17632/wvyhtrff73
title: Visual literacy test - Validation and reliability data

description: The files presented contain the data obtained and processed, corresponding to the process of validation and reliability of the instrument.

1. Validation focus group: Categories and subcategories of analysis of the data obtained in the focus group and the results based on the items mentioned.
2. Content validation coefficient: Evaluation of the experts by category and item and processing to obtain the CVC.
3. Quiz responses: Responses of the 255 subjects who answered the test, with which the reliability and degree of difficulty of the items that make up the test were obtained. 
4. Visual literacy test: Design of the visual literacy test applied in the pilot study.
DOI: 10.6084/m9.figshare.1330132.v1
title: Dataset for classification of signaling proteins based on molecular star graph descriptors using machine-learning models

description: The positive group of 608 signaling protein sequences was downloaded as FASTA format from Protein Databank (Berman et al., 2000) by using the “Molecular Function Browser” in the “Advanced Search Interface” (“Signaling (GO ID23052)”, protein identity cut-off = 30%). The negative group of 2077 non-signaling proteins was downloaded as the PISCES CulledPDB (http://dunbrack.fccc.edu/PISCES.php) (Wang & R. L. Dunbrack, 2003) (November 19th, 2012) using identity (degree of correspondence between two sequences) less than 20%, resolution of 1.6 Å and R-factor 0.25. The full dataset is containing 2685 FASTA sequences of protein chains from the PDB databank: 608 are signaling proteins and 2077 are non-signaling peptides. This kind of unbalanced data is not the most suitable to be used as an input for learning algorithms because the results would present a high sensitivity and low specificity; learning algorithms would tend to classify most of samples as part of the most common group. To avoid this situation, a pre-processing stage is needed in order to get a more balanced dataset, in this case by means of the synthetic minority oversampling technique (SMOTE). In short, SMOTE provides a more balanced dataset using an expansion of the lower class by creating new samples, interpolating other minority-class samples. After this pre-processing, the final dataset is composed of 1824 positive samples (signaling protein chains) and 2432 negative cases (non-signaling protein chains). Paper is available at: http://dx.doi.org/10.1016/j.jtbi.2015.07.038 Please cite: Carlos Fernandez-Lozano, Rubén F. Cuiñas, José A. Seoane, Enrique Fernández-Blanco, Julian Dorado, Cristian R. Munteanu, Classification of signaling proteins based on molecular star graph descriptors using Machine Learning models, Journal of Theoretical Biology, Volume 384, 7 November 2015, Pages 50-58, ISSN 0022-5193, http://dx.doi.org/10.1016/j.jtbi.2015.07.038.(http://www.sciencedirect.com/science/article/pii/S0022519315003999)
DOI: 10.6084/m9.figshare.27928537.v1
title: Additional file 5 of The IMPACT Survey: the humanistic impact of osteogenesis imperfecta in adults

description: Supplementary Material 5
DOI: 10.6084/m9.figshare.27246606.v1
title: Supplementary Material for: Mastery learning guided by AI is superior to directed self-regulated learning in flexible bronchoscopy training – an RCT.

description: Introduction: Simulation-based training has proven effective for learning flexible bronchoscopy. However, no studies have tested the efficacy of training towards established proficiency criteria i.e., mastery learning (ML). We wish to test the effectiveness of ML compared to Directed Self-Regulated Learning (DSRL) on novice bronchoscopists’ end-of-training performance.
Methods: In a standardized simulated setting, novices without prior bronchoscopy experience trained using an artificial intelligence (AI) guidance system that automatically recognizes the bronchial segments. They were randomized into two groups: the ML group and the DSRL group. The ML group trained until they completed two procedures meeting the proficiency targets: 18 inspected segments, 18 structured progressions, &lt;120 seconds procedure time. The DSRL group trained until they no longer perceived any additional benefits from training. Both groups then did a finalizing test, without the AI-guidance enabled. 
Results: 24 participants completed the study, with 12 in each group. Both groups had a high mean number of inspected segments (ML=17.2 segments, DSRL=17.3 segments, P=.85) and structured progressions (ML=15.5 progressions, DSRL=14.8 progressions, P=.58), but the ML group performed the test procedure significantly faster (ML=107 seconds, DSRL=180 seconds, P&lt;.001). The ML did not spend significantly longer time training (ML=114 minutes, DSRL=109 minutes, P=.84).
Conclusions: ML is a very efficient training form allowing novice trainees to learn how to perform a thorough, systematic, and quick flexible bronchoscopy. ML does not require longer time spent training compared to DSRL, and we therefore recommend training of future bronchoscopists by this method.
DOI: 10.6084/m9.figshare.24278590.v1
title: Supplementary Material for: Risk factors for neurodevelopmental impairment at two- and five years corrected age in preterm infants with established bronchopulmonary dysplasia

description: Introduction: The objective of this study was to identify risk factors for neurodevelopmental impairment (NDI) at two- and five-years corrected age (CA) in a cohort of preterm infants with established bronchopulmonary dysplasia (BPD). Methods: This single center retrospective cohort study included infants born between 2009 and 2016 at a gestational age &lt; 30 weeks with moderate or severe BPD at 36 weeks’ postmenstrual age. Perinatal characteristics, (social) demographics, and comorbidities were collected from the electronic patient records. Odds ratios for NDI were calculated with univariate and multivariate logistic regression analyses adjusting for potential confounders. Results: Of the 602 eligible infants, 123 infants were diagnosed with BPD. NDI was present in 30.3%, and 56.1% at two- and five-years CA, respectively. The only independent risk factors associated with NDI in the multivariate analyses were birthweight (adjusted odds ratio (aOR) 0.74, 95%CI 0.57-0.95; aOR 0.70, 95%CI 0.54-0.91, respectively), small for gestational age (SGA) (aOR 3.25, 95%CI 1.09-9.61; aOR 5.44, 95%CI 1.62-18.2, respectively) at both time points, and male gender at five-years CA (OR 2.49, 95%CI 1.11-5.57). Discussion/Conclusion: Birthweight and SGA are independent risk factors for NDI at two- and five-years CA and male gender at five-years CA in preterm infants with BPD. In contrast, well known other risk factors for NDI in the general population of preterm infants, such as GA, maternal education, and neonatal comorbidities were not independently associated with NDI.
DOI: 10.6084/m9.figshare.25288027.v1
title: Supplementary Material for: Reduced Proliferative Capacity and Defense against <i>Staphylococcus aureus</i> in Human Nasal Mucosal Epithelium Lacking ZNF365

description: <b><i>Introduction:</i></b> Chronic rhinosinusitis with nasal polyps (CRSwNP) is a common chronic inflammatory disease of the nose characterized by barrier disruption and environmental susceptibility, and the deletion of ZNF365 may be a factor inducing these manifestations. However, there is no study on the mechanism of action between CRSwNP and ZNF365. Therefore, this study focuses on the effect of the zinc finger protein ZNF365 on the proliferation of nasal mucosal epithelial cells and their defense against <i>Staphylococcus aureus</i> (<i>S. aureus</i>). <b><i>Methods:</i></b> Immunohistochemistry and Western blot were applied to verify the changes of ZNF365 expression in nasal polyp tissues and control tissues, as well as in primary epithelial cells. ZNF365 was knocked down in human nasal mucosa epithelial cell line (HNEpc), and the proliferation, migration, and transdifferentiation of epithelium were observed by immunofluorescence, QPCR, CCK8, and cell scratch assay. The changes of mesenchymal markers and TLR4-MAPK-NF-κB pathway were also observed after the addition of <i>S. aureus</i>. <b><i>Results:</i></b> ZNF365 expression was reduced in NP tissues and primary nasal mucosal epithelial cells compared to controls. Knockdown of ZNF365 in HNEpc resulted in decreased proliferation and migration ability of epithelial cells and abnormal epithelial differentiation (decreased expression of tight junction proteins). <i>S. aureus</i> stimulation further inhibited epithelial cell proliferation and migration, while elevated markers of epithelial-mesenchymal transition and inflammatory responses occurred. <b><i>Conclusion:</i></b> ZNF365 is instrumental in maintaining the proliferative capacity of nasal mucosal epithelial cells and defending against the invasion of <i>S. aureus</i>. The findings suggest that ZNF365 may participate in the development of CRSwNP.
DOI: 10.17632/ht42k92fbt
title: Data for: How urban green management is influencing passerine birds’ nesting in the Mediterranean: a case study in a Catalan city

description: Inventory of the total vegetation of the urban area of the city of Valls in 2014
DOI: 10.17632/dbh5xsyvg5
title: Program for stability and accuracy analysis of finite difference methods

description: Title of program: MODST Catalogue Id: ACDF_v1_0 Nature of problem One of the main problems in solving partial differential equations using finite difference methods is the evaluation of various properties of a finite difference algorithm such as order of accuracy, consistency and particularly stability. These problems must almost always be solved by hand. Using the analytical programming language REDUCE 2, the program determines the above properties of finite difference algorithms for simple partial differential equations. Versions of this program held in the CPC repository in Mendeley Data ACDF_v1_0; MODST; 10.1016/0010-4655(84)90169-3 This program has been imported from the CPC Program Library held at Queen's University Belfast (1969-2019)
DOI: 10.6084/m9.figshare.27977163.v1
title: ChatCPT Data EN (DeepL)

description: Input and output data from long-term learning in mathematical statistics using ChatGPT, translated by DeepL.