cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.57770/fnb1ks
title: Health Services Utilisation in Breast Cancer Survivors in Taiwan

description: Surveillance guidelines for breast cancer survivors recommend regular history and physical and mammography, and against routine imaging for detecting distant metastasis. Stage 0, I, II breast cancer cases treated at a major cancer center were identified from the Taiwan Cancer Registry. We used multivariable negative binomial and logistic regression analyses on institutional claims data to examine factors contributing to utilisation patterns of surveillance visits and tests in disease-free survivors. The mean number of surveillance visits during months 13 to 60 after cancer treatment initiation was 18.5 (SD 8.2) among the 2,090 breast cancer survivors followed for at least five years. After adjusting for patient and disease factors, the number of visits was the highest among patients mainly followed by medical oncologists compared to surgeons and radiation oncologists. Patient cohorts treated in more recent years had lower number of visits associated with care coordination effort, the adjusted mean being 19.2 visits for the 2002 cohort, and 16.3 visits for the 2008 cohort (p , 0.0001). Although imaging tests were highly utilised, there was a significant decrease in tumor marker testing from the 2002 to the 2008 treatment cohort (adjusted rate 99.4% to 35.1% respectively, p , 0.0001) in association with an institutional guideline change.
DOI: 10.4121/8b025bf5-97b4-4708-a590-a8cdf4f662b0
title: Data pertaining to the paper Encapsulated crystallisation inhibitor as a long-term solution to mitigate salt damage in hydraulic mortars

description: The paper follows an experimental approach to investigate the effect of capsules on the properties of mortar and the effect of the encapsulated inhibitor on the salt weathering resistance of various mortars.<br>The data is added a zipped file with a readme file in each folder explaining the data, data types and the way to process the data. The type of files include ".xlsx", ."xls", ".txt" for alphanumeric data, ".tiff" and ".jpg" for image related data and ".m" are MATLAB files for processing the data.
DOI: 10.4121/8b025bf5-97b4-4708-a590-a8cdf4f662b0.v2
title: Data pertaining to the paper Encapsulated crystallisation inhibitor as a long-term solution to mitigate salt damage in hydraulic mortars

description: The paper follows an experimental approach to investigate the effect of capsules on the properties of mortar and the effect of the encapsulated inhibitor on the salt weathering resistance of various mortars.<br>The data is added a zipped file with a readme file in each folder explaining the data, data types and the way to process the data. The type of files include ".xlsx", ."xls", ".txt" for alphanumeric data, ".tiff" and ".jpg" for image related data and ".m" are MATLAB files for processing the data.
DOI: 10.5281/zenodo.13120535
title: HER2/neu-specific T-cells

description: Single-cell RNA-seq data of HER2/neu-specific T-cells genereated with the BD Rhapsody™ system.

Donor information: 3 healthy subjects, 2 male (SampleTag04, SampleTag05), 1 female (SampleTag06).

Cell preparation: HER2/neu-specific T-cells were obtained via a Tetramer-based sorting of the naturally-occuring anti-CD3 and anti-CD28-activated T-cells co-cultured with the Dendritic cells that were maturated by a KIFGSLAFL peptide. 

Single-cell analysis system: BD Rhapsody™

Library strategy: 5' mRNA sequencing

Library preparation protocol: BD Rhapsody™ TCR/BCR Full Length, Targeted mRNA, and Sample Tag Library Preparation

mRNA panel: BD Rhapsody™ Immune Response Panel HS

BD Pipeline version: 1.11.1L
DOI: 10.5281/zenodo.13120536
title: HER2/neu-specific T-cells

description: Single-cell RNA-seq data of HER2/neu-specific T-cells genereated with the BD Rhapsody™ system.

Donor information: 3 healthy subjects, 2 male (SampleTag04, SampleTag05), 1 female (SampleTag06).

Cell preparation: HER2/neu-specific T-cells were obtained via a Tetramer-based sorting of the naturally-occuring anti-CD3 and anti-CD28-activated T-cells co-cultured with the Dendritic cells that were maturated by a KIFGSLAFL peptide. 

Single-cell analysis system: BD Rhapsody™

Library strategy: 5' mRNA sequencing

Library preparation protocol: BD Rhapsody™ TCR/BCR Full Length, Targeted mRNA, and Sample Tag Library Preparation

mRNA panel: BD Rhapsody™ Immune Response Panel HS

BD Pipeline version: 1.11.1L
DOI: 10.5281/zenodo.7990869
title: Data associated with Spatial predictors of immunotherapy response in triple negative breast cancer

description: This dataset contains all the IMC data associated with Wang et al. Spatial predictors of immunotherapy response in triple negative breast cancer, 2023. 


The zip file NTPublic contains:



	
Raw multiplexed image data, image masks (cell, nuclear, epithelial, vessel), spillover matrix for signal compensation, antibody panel information, clinical data
	
Processed single-cell data
	
Code for analysis and creating plots



Please read the accompanying DataGuide.pdf for folder structure guide and information on both the raw and processed data.


Please read the accompanying CodeGuide.pdf to reproduce published figures. 
description: Funding: This research was funded by CRUK (grants A25815, A27463 and A29580).

THIS DATASET IS AVAILABLE THROUGH THIS REPOSITORY FOR ACADEMIC NON-COMMERCIAL USE ONLY.
THE DATASET CAN ONLY BE USED BY THE APPLICANTS NAMED ON THE APPLICATION AND FOR THE INTENDED USE SPECIFIED IN THE APPLICATION. COPY OR DISTRIBUTION OF THIS DATASET IS STRICTLY PROHIBITED.
DOI: 10.5281/zenodo.10819963
title: Clinical isolation of Saccharomyces cerevisiae antibiotics-sensitive phenotypes dataset in a women's and children's hospital

description: Clinical isolation of Saccharomyces cerevisiae antibiotics-sensitive phenotypes dataset in a women's and children's hospital (Candida albicans served as the control group).
DOI: 10.5281/zenodo.10819964
title: Clinical isolation of Saccharomyces cerevisiae antibiotics-sensitive phenotypes dataset in a women's and children's hospital

description: Clinical isolation of Saccharomyces cerevisiae antibiotics-sensitive phenotypes dataset in a women's and children's hospital (Candida albicans served as the control group).
DOI: 10.5281/zenodo.13120603
title: Fictive reactions validated by TTL with USPTO as source of molecules - equilibrated subset (1M)
DOI: 10.5281/zenodo.13120604
title: Fictive reactions validated by TTL with USPTO as source of molecules - equilibrated subset (1M)
DOI: 10.57770/x9k5qe
title: A clinical clerkship collaborative program in Taiwan: Acquiring core clinical competencies through patient care responsibility

description: Background/Purpose: Traditionally, clinical clerkship training in Taiwan does not provide medical students with sufficient patient care responsibilities and often results in inadequate clinical skills. Methods: We implemented a pilot clerkship program at a comprehensive cancer center that emphasizes core clinical competency through direct patient care and dedicated faculty and mentors. Students were an integral part of the patient care team held accountable for providing coordinated and holistic care. Students’ self-assessment of clinical competencies, faculty evaluation, and objective structured clinical examination were compared against their peers trained by traditional clerkship at a main teaching hospital. Results: Fifty medical students completed the clerkship program in the first 3 years. At the end of the clerkship, participants rated themselves significantly higher than their peers in almost all patient care and clinical skill domains. The most significant areas included physical examination, clinical reasoning, developing management plan, holistic approach, handling ethical issues, and time management skills. The students rated their clerkship teachers significantly higher in time spent with students, skills and enthusiasm in teaching, as well as giving students appropriate patient care responsibilities. There was no significant difference in the end-of-clerkship objective structured clinical examination performance, but participants of the program achieved better grades in their subsequent internship.
DOI: 10.57770/nhqmon
title: Attitude towards hereditary cancer risk management among women with cancer in Taiwan

description: Abstract Background Risk management intentions prior to genetic counseling predict risk management uptake following genetic test-ing. Limited studies examined the attitude and understanding towards genetic counseling/testing in underserved countries. The purposes of this study were to explore knowledge and attitude towards genetic counseling, testing, and risk management for breast and ovarian cancer, and to understand the factors infuencing risk management intentions in women with cancer in Taiwan. Methods Cross-sectional with correlational design was used in this study. Participants were enrolled for genetic testing based on clinical criteria suspected of having hereditary cancer. Survey was conducted using a standardized questionnaire including (1) demographics and personal/family history of cancer; (2) prior experience or consideration of genetic testing and reasons for not considering; (3) perception and attitude towards genetic counseling; and (4) intentions for risk management with a hypothetical BRCA1 mutation status. Multinomial logistic regression was used to analyze the predictors of participants’ intentions for cancer risk management strategies. Results A total of 430 women with cancer were analyzed in which 51.6% had family history of cancer in frst-degree relatives. Only 30.7% had considered genetic testing and 28.4% had known about genetic counseling prior to the study. When prompted with the services of genetic counseling, the attitude towards genetic counseling was fairly positive (score of 19.8±2.9 out of 25). Given hypothetical BRCA1 mutation status, enhanced breast cancer screening with annual breast MRI was much more accepted than cancer risk reducing interventions. More positive attitude towards genetic counseling (each score point increase) was associated with higher odds of intention for breast MRI (OR 1.20, 95% CI 1.09–1.32) and preventive tamox-ifen (OR 1.11, 95% CI 1.02–1.22). Having considered genetic testing prior to the study was associated with higher odds of intention for all four risk management strategies: breast MRI (OR 2.99, 95% CI 1.46–6.11), preventive tamoxifen (OR 1.79, 95% CI 1.00–3.17), risk-reducing mastectomy (OR 2.24, 95% CI 1.13–4.42), and risk-reducing salpingo-oophorectomy (OR 2.69, 95% CI 1.27–6.93). Conclusion Knowledge of genetic testing and positive attitude towards genetic counseling were associated with increased willingness to consider cancer risk management strategies for hereditary breast and ovarian cancer syndrome. Given the limited knowledge on genetic testing and counseling in the studied population, increasing public awareness of these services may increase adoption of the risk management strategies.
DOI: 10.57770/e4knqt
title: Uptake of genetic testing among patients seeking cancer genetic counseling in Taiwan

description: Abstract Genetic testing is becoming increasingly available and affordable. Understanding the reasons for individual decisions about genetic testing may assist in the identification of clinically appropriate use of genetic counseling and genetic testing resources. With the ongoing development of cancer genetic counseling services in Taiwan, we conducted this study to understand the characteristics of those seeking cancer genetic counseling and genetic testing and the predictors for undergoing genetic testing after counseling. Cross-sectional with correlational design was used in this study. Surveys completed by patients visiting the genetic counseling clinic at the cancer center included demographics, personal and family history of cancer, and questions on attitudes toward genetic counseling and genetic testing. Multinomial logistic regression was used to analyze the predictors of decision to undergo genetic testing. A total of 120 participants between the years 2018 and 2021 were analyzed, of which 54.2% were referred by health care professionals. The majority (76.7%) had a personal history of cancer and 50% had breast cancer. Over half (53.3%) had a strong family history of cancer defined as two or more 1st-degree relatives having cancer at a young age. Only 35.8% decided to receive genetic testing right after counseling and 47.5% were undecided. The main reason for hesitation or not pursuing testing was cost (41.4%). Multivariate logistic regression analysis showed that a positive attitude toward genetic counseling was significantly associated with the uptake of genetic testing (Odds ratio 7.60, 95% CI 2.34–24.66, p&lt; 0.001). Given the significant number of individuals undecided about genetic testing after counseling, decision aid could be developed to support genetic counseling and increase satisfaction with the testing decision.
DOI: 10.57770/0faeix
title: Germline breast cancer susceptibility gene mutations and breast cancer outcomes

description: Abstract Background: It is unclear whether germline breast cancer susceptibility gene mutations affect breast cancer related outcomes. We wanted to evaluate mutation patterns in 20 breast cancer susceptibility genes and correlate the mutations with clinical characteristics to determine the effects of these germline mutations on breast cancer prognosis. Methods: The study cohort included 480 ethnic Chinese individuals in Taiwan with at least one of the six clinical risk factors for hereditary breast cancer: family history of breast or ovarian cancer, young age of onset for breast cancer, bilateral breast cancer, triple negative breast cancer, both breast and ovarian cancer, and male breast cancer. PCR-enriched amplicon-sequencing on a next generation sequencing platform was used to determine the germline DNA sequences of all exons and exon-flanking regions of the 20 genes. Protein-truncating variants were identified as pathogenic. Results: We detected a 13.5% carrier rate of pathogenic germline mutations, with BRCA2 being the most prevalent and the non-BRCA genes accounting for 38.5% of the mutation carriers. BRCA mutation carriers were more likely to be diagnosed of breast cancer with lymph node involvement (66.7% vs 42.6%; P = 0.011), and had significantly worse breast cancer specific outcomes. The 5-year disease-free survival was 73.3% for BRCA mutation carriers and 91.1% for non-carriers (hazard ratio for recurrence or death 2.42, 95% CI 1.29–4.53; P = 0.013). After adjusting for clinical prognostic factors, BRCA mutation remained an independent poor prognostic factor for cancer recurrence or death (adjusted hazard ratio 3.04, 95% CI 1.40–6.58; P = 0.005). Non-BRCA gene mutation carriers did not exhibit any significant difference in cancer characteristics or outcomes compared to those without detected mutations. Among the risk factors for hereditary breast cancer, the odds of detecting a germline mutation increased significantly with having bilateral breast cancer (adjusted odds ratio 3. 27, 95% CI 1.64–6.51; P = 0.0008) or having more than one risk factor (odds ratio 2.07, 95% CI 1.22–3.51; P = 0.007). Conclusions: Without prior knowledge of the mutation status, BRCA mutation carriers had more advanced breast cancer on initial diagnosis and worse cancer-related outcomes. Optimal approach to breast cancer treatment for BRCA mutation carriers warrants further investigation.
DOI: 10.57770/kd8shy
title: Mismatch Repair (MMR) Gene Mutation Carriers Have Favorable Outcome in Colorectal and Endometrial Cancer: A Prospective Cohort Study

description: Simple Summary: Germline and somatic deficiencies of mismatch repair proteins (MMRd) are related to colorectal and endometrial cancers, but the survival impact in Asian patients remains unclear. We investigated the prevalence and outcomes of patients with germline and/or somatic MMRd. Germline and somatic MMRd were determined by gene sequencing and protein staining of tumor samples, respectively. We found that colorectal and endometrial cancer patients with germline MMRd have favorable survival outcomes compared to those without, regardless of somatic MMRd status. These findings highlight the importance of germline genetic testing when tumor MMRd is detected.
DOI: 10.15468/dl.nra663
title: Occurrence Download

description: A dataset containing 150701 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Stuckenia pectinata (L.) Börner)",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 "HasGeospatialIssue is false",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Specimen)"
 ]
 }
 }
 ]
}

 The dataset includes 150701 records from 555 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0040895-240626123714530/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.12793236
title: Northern Hemisphere ice sheets and ocean interactions during the last glacial period in a coupled ice sheet-climate model

description: This archive provides the GRISLI ice sheet model and iLOVECLIM model outputs as part of the manuscript "Northern Hemisphere ice sheets and ocean interactions during the last glacial period in a coupled ice sheet-climate model".

Contact: louise.abot@locean.ipsl.fr
DOI: 10.4121/bad723e5-c0ca-4725-a4c1-8314a41a046a
title: Data underlying the PhD thesis: A numerical and experimental study of ratcheting for head check initiation in rails

description: This dataset is to supplement the doctoral dissertation of 'A numerical and experimental study of ratcheting for head check initiation in rails'. The dataset contains the multiple simulation and test data that demonstrate the results of the each of the main chapters of this dissertation. The data and coding in Chapter 1 explains the elasto-plastic behaviours of rail steels. Data provided for Chapter 2 demonstrates the simulated ratcheting behaviours in rails with a new FE wheel--rail rolling contact modelling designed for this study. For Chapter 3, the data contains the surface and subsurface contact stress states post-processed from wheel-rail rolling contact with a cylindrical and a conical wheel. In Chapter 4, data from the uniaxial monotonic and cyclic tests and the relevant calibrated constitutive models are summarised and presented accompanied by the Python codes. The final Chapter 5 contains the data of the ratcheting simulation in rails that demonstrate the detailed ratcheting behaviour of the two tested rail steels under wheel--rail rolling contacts.
DOI: 10.4121/bad723e5-c0ca-4725-a4c1-8314a41a046a.v1
title: Data underlying the PhD thesis: A numerical and experimental study of ratcheting for head check initiation in rails

description: This dataset is to supplement the doctoral dissertation of 'A numerical and experimental study of ratcheting for head check initiation in rails'. The dataset contains the multiple simulation and test data that demonstrate the results of the each of the main chapters of this dissertation. The data and coding in Chapter 1 explains the elasto-plastic behaviours of rail steels. Data provided for Chapter 2 demonstrates the simulated ratcheting behaviours in rails with a new FE wheel--rail rolling contact modelling designed for this study. For Chapter 3, the data contains the surface and subsurface contact stress states post-processed from wheel-rail rolling contact with a cylindrical and a conical wheel. In Chapter 4, data from the uniaxial monotonic and cyclic tests and the relevant calibrated constitutive models are summarised and presented accompanied by the Python codes. The final Chapter 5 contains the data of the ratcheting simulation in rails that demonstrate the detailed ratcheting behaviour of the two tested rail steels under wheel--rail rolling contacts.
DOI: 10.5281/zenodo.13120336
title: Xenolith Constraints on Lithospheric Architecture and Mantle Geochemistry of Australia

description: Compilation of new and previously analysed mantle-derived clinopyroxenes and garnets from kimberlites, lamproites and related rocks from across Australia.
DOI: 10.5281/zenodo.13120337
title: Xenolith Constraints on Lithospheric Architecture and Mantle Geochemistry of Australia

description: Compilation of new and previously analysed mantle-derived clinopyroxenes and garnets from kimberlites, lamproites and related rocks from across Australia.
DOI: 10.15468/dl.v66fbg
title: Occurrence Download

description: A dataset containing 27 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Continent is Asia",
 "Country is China",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "TaxonKey is Panthera pardus (Linnaeus, 1758)"
 ]
}

 The dataset includes 27 records from 9 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0040906-240626123714530/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.hauf8w
title: Occurrence Download

description: A dataset listing the 26 species recorded in GBIF matching the query:
{
 "and" : [
 "Country is Ukraine",
 "Geometry POLYGON((22.87917 49.06301,22.53999 49.10601,22.10648 48.4169,22.89619 47.95397,23.21515 47.99523,24.11677 47.91495,24.19697 47.89981,24.27894 47.9036,24.42561 47.9461,24.55167 47.95733,24.1593 48.41361,23.656 48.761,22.87917 49.06301))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "TaxonKey is Chiroptera"
 ]
}

 The dataset's 26 records were derived from 10 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0040903-240626123714530/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.snkzvw
title: Occurrence Download

description: A dataset containing 273874 species occurrences available in GBIF matching the query:
{
 "and" : [
 "OccurrenceStatus is Present",
 "TaxonKey is Blattodea"
 ]
}

 The dataset includes 273874 records from 1125 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0040904-240626123714530/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.gmfd4x
title: Occurrence Download

description: A dataset containing 359 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Taraxacum apenninum (Ten.) DC.",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 359 records from 8 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0079710-231120084113126/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.jsaqmq
title: Occurrence Download

description: A dataset containing 627 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Mexico",
 "HasCoordinate is true",
 "TaxonKey is Camponotus atriceps (Smith, 1858)",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 627 records from 15 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0000167-190813142620410/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.yryj2z
title: Occurrence Download

description: A dataset containing 3 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Cyperus tempeae G.C.Tucker"
 ]
}

 The dataset includes 3 records from 3 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0154489-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.