cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.1543416.v1
title: Transgenic Mice Tumor Growth

description: This file contains measurements of skin cancer tumors, measured on transgenic mice. The data contain measurements on untreated mice and mice that went through trteatment
DOI: 10.6084/m9.figshare.21749834.v1
title: Supplementary Material for: Association of Body Shape Index with Cerebral Small Vessel Disease

description: Introduction: A body shape index (ABSI) is an anthropometric index designed to reflect the influence of visceral fat. ABSI has been previously associated with various atherosclerosis, metabolic diseases, and cardiovascular diseases; however, relatively few studies have been conducted on cerebrovascular disease. In this study, we evaluated the association between ABSI and cerebral small vessel disease (cSVD) in health check-up participants. Methods: We evaluated consecutive health check-up participants between January 2006 and December 2013. As subtypes of cSVD, we quantitatively measured the volume of white matter hyperintensity (WMH) and qualitatively measured the presence of silent brain infarct (SBI) and cerebral microbleed (CMB). ABSI was calculated according to the following formula: ABSI (m11/6/kg-2/3) = waist circumference (m) / [body mass index (kg/m2)2/3 × height (m)1/2]. Results: A total of 3,219 health check-up participants were assessed (median age, 56 years; male sex, 54.0%). In the multivariable analysis, ABSI was significantly associated with WMH volume (β = 0.107, 95% confidence interval [CI] = 0.013 to 0.200), SBI (adjusted odds ratio [aOR] = 1.62, 95% CI = 1.14-2.31) and CMB (aOR = 1.64, 95% CI = 1.16-2.33) after adjusting for confounders (per 100 m11/6/kg-2/3). Furthermore, ABSI showed a dose-response relationship with the burden of each cSVD pathology. Conclusions: High ABSI was associated with a higher burden of cSVD in health check-up participants. As ABSI showed close associations with all subtypes of cSVD, visceral fat may be a common risk factor penetrating cSVD pathologies.
DOI: 10.6084/m9.figshare.25603188.v1
title: Annotation dataset of Cinnamomum chago

description: Genome annotation data including organelle.
DOI: 10.17632/bnsjg4t8mh
title: Data associated with "Unexpected transformations during pyrroloiminoquinone biosynthesis" JACS 2024 146(20):14235.

description: Data associated with all figures in the main text and Supporting Information
DOI: 10.17632/r5db8gbgxs
title: Task-irrelevant visual perceptual learning in children and adults

description: Task-irrelevant visual perceptual learning (VPL) was examined in a group of elementary school age children (7 – 10 years old, n = 20 subjects) and a group of young adults (18 – 31 years old, n = 20 subjects). The experiment consisted of several sessions conducted on separate days. In the first session subjects’ thresholds for coherent motion detection were measured. In the second session subjects completed a pretest for discrimination performance of different coherent motion directions. From the third to the fourteenth session subjects performed a rapid serial visual presentation (RSVP) task at screen center while coherent motion in different directions was exposed as task-irrelevant in the visual periphery. Prior to the experiment each subject was randomly assigned to two different exposure conditions (n = 10 subjects for each age group for each exposure condition). There was a threshold exposure condition in which coherent motion was exposed at the individual threshold for coherent motion detection. There was also a suprathreshold exposure condition in which coherent motion was exposed at 4.0 x individual threshold for coherent motion detection. In each trial of the RSVP one coherent motion direction, termed the “task-irrelevant learning direction” was exclusively paired with RSVP targets, while other coherent motion directions were randomly paired with RSVP distractors (“untrained directions”). Finally, in the fifteenth session subjects completed a posttest in motion direction discrimination exactly as in the pretest. The results show that subjects in both age groups improved significantly on the RSVP over the course of the exposure sessions. In the threshold exposure condition subjects in each age group significantly improved discrimination performance for the task-irrelevant learning direction from pretest to posttest. In the suprathreshold exposure condition children significantly improved discrimination performance for the task-irrelevant learning direction from pretest to posttest, while young adults significantly decreased discrimination performance. Furthermore, subjects also completed the Useful Field of View (UFOV) subtests for processing speed, divided attention and selective attention. The discrimination performance increase in the suprathreshold exposure condition in children was significantly correlated with the selective attention ability, such that children with greater discrimination performance increase from pretest to posttest also tended to show greater selective attention ability. No such association was observed either for young adults or for any other UFOV subtest.
DOI: 10.6084/m9.figshare.12085551.v1
title: Supplementary Material for: Increased Release of Proinflammatory Proteins in Primary Human Adipocytes and Activation of the Inflammatory NFĸB, p38, and ERK Pathways upon Omentin Treatment

description: <b><i>Objectives:</i></b> To investigate the impact of omentin on the release of inflammation-related biomarkers and inflammatory pathways in primary human adipocytes. <b><i>Methods:</i></b> Adipocytes were treated with or without omentin (500 and 2,000 ng/mL), and the supernatants were analyzed for inflammation-related biomarkers using proximity extension assay technology. Potential upstream regulators of the omentin-stimulated proteins were identified using Ingenuity Pathway Analysis. Protein levels of components of inflammatory pathways were measured using Western blotting. <b><i>Results:</i></b> 2,000 ng/mL omentin induced the release of 30 biomarkers 97.1 ± 31.1-fold in the supernatants (all <i>p</i> &lt; 0.05). Most biomarkers were proin­flammatory chemokines and cytokines. We identified the transcription factor nuclear factor “kappa-light-chain-enhancer” of activated B cells (NFĸB) and the kinases p38 and extracellular signal-regulated kinase (ERK)1/2 as potential upstream regulators in silico. On the cellular level, treatment with 2,000 ng/mL omentin for 24 h enhanced the phosphorylation levels of NFĸB 2.1 ± 0.3-fold (<i>p</i> &lt; 0.05), of p38 2.6 ± 0.4-fold (<i>p</i> &lt; 0.05), and of ERK1/2 1.8 ± 0.2-fold (<i>p</i> &lt; 0.05). <b><i>Conclusions:</i></b> These data argue that omentin exerts proinflammatory effects through the activation of the inflammatory NFĸB, p38, and ERK1/2 pathways in cultured primary adipocytes.
DOI: 10.6084/m9.figshare.12925010.v1
title: Supplementary Material for: Placebo Response in Phase 3 Trials of Systemic Therapies for Moderate-to-Severe Plaque Psoriasis: A Systematic Review and Meta-Analysis

description: <b><i>Background:</i></b> Wide fluctuations in placebo responses have been reported in phase 3 trials of systemic therapies for moderate-to-severe plaque psoriasis. <b><i>Methods:</i></b> In this systematic review and meta-analysis, we assessed placebo responses in phase 3 trials of systemic therapies for moderate-to-severe plaque psoriasis. The medical databases PubMed Medline, Embase, and Web of Science were searched for studies reporting on phase 3 psoriasis trials. A proportion meta-analysis determined the proportion of placebo-treated psoriasis patients obtaining a 75, 90, or 100% reduction in Psoriasis Area and Severity Index (PASI), that is, PASI75, PASI90, or PASI100, respectively, at week 12. In the assessment of PASI75 response, 44 trials with a total number of 7,972 patients were included. <b><i>Conclusion:</i></b> In pooled analyses, 5.2% (95% CI 4.7–5.7%) obtained PASI75, 2.1% (95% CI 1.7–2.4%) obtained PASI90, and 0.3% (95% CI 0.1–0.5%) obtained PASI100 among placebo receivers. No temporal changes were observed. The overall proportion of placebo responders in phase 3 psoriasis trials is low and does not appear to be increasing in recent years.
DOI: 10.6084/m9.figshare.24799443.v1
title: Fordító és tolmács hallgatók pályakövetése / Career path survey of translator and interpreter graduates (ELTE Eötvös Loránd University)

description: A jelen kérdőíves kutatás az ELTE BTK Fordító- és Tolmácsképző Tanszékének öregdiákjai körében készült azzal a céllal, hogy a tanszék és elődintézményei (FTCS, FTK) fennállásának 50. évfordulóján átfogó képet kapjunk a végzett hallgatók karrierútjáról, valamint a képzéssel és a nyelvi közvetítői szakmával kapcsolatos véleményükről.Az online felmérés 28 kérdésből állt, kitöltése anonim és önkéntes volt. A kérdőívet a tanszék alumni levelezőlistáján és az egyetem elektronikus rendszerén (ELTE Neptun) keresztül osztottuk meg a végzett hallgatókkal. A 381 kitöltés megközelítőleg 25 százalékos válaszadási arányt eredményezett.<br><b>Közzétett fájlok (magyar és angol):</b><i>Pályakövetési kérdőív (Pdf)</i><i>Pályakövetési kérdőív összesített adatok (Pdf)</i><i>Pályakövetési kérdőív részletes kvantitatív adatok (Excel)</i><br>The present survey was conducted among alumni of the Department of Translation and Interpreting (FTT), Eötvös Loránd University, Hungary with the aim to get a comprehensive picture of the career paths of graduates and their opinions about the training and the language mediation industry -- on the occasion of the 50th anniversary of the department and its predecessor institutions (FTCS, FTK).The online survey consisted of 28 questions, completed anonymously and on a voluntary basis. The questionnaire was shared with graduates via the department's alumni mailing list and the university's electronic system (ELTE Neptun). The 381 completions resulted in a response rate of approximately 25%.<br><b>Published files (English and Hungarian):</b><i>Career Tracking Questionnaire (Pdf)</i><i>Accumulated data of the Career Tracking Questionnaire (Pdf)</i><i>Detailed quantitative data of the Career Path Questionnaire (Excel)</i>
DOI: 10.6084/m9.figshare.1241506.v1
title: Data for "C60 fullerene promotes monolayer collapse"

description: This archive contains the starting structures (gro), topology files (top, itp), and simulation parameter files (mdp) for the simulations reported in the article entitled "C60 fullerene promotes monolayer collapse" by Jonathan Barnoud, Laura Urbini, and Luca Monticelli.
DOI: 10.6084/m9.figshare.12714425.v1
title: Supplemental Materials for the Philippine Journal of Science paper entitled, "Resistance gene analogs of mango: insights on molecular defenses and evolutionary dynamics"

description: In this study, transcriptomic data (from diverse mango varieties) and whole-genome data (from Alphonso variety) were utilized in order to obtain a comprehensive analysis of mango RGAs
DOI: 10.6084/m9.figshare.15263658.v1
title: Supplementary Material for: Long-Term Outcomes after Early Neonatal Hyperglycemia in VLBW Infants: A Systematic Review

description: <b><i>Introduction:</i></b> Long-term effects of early hyperglycemia in VLBW infants are poorly characterized. The objective of this study was to systematically review the effect of early hyperglycemia on growth, metabolic health, and neurodevelopment after neonatal intensive care unit discharge in VLBW infants. <b><i>Methods:</i></b> The systematic review was conducted in accordance with the PRISMA guidelines. A study protocol was registered in PROSPERO (CRD42019123335). Data sources included Ovid MEDLINE, Embase, Cochrane Library, CINAHL, and Scopus. Selected studies included infants with a blood glucose concentration &gt;150 mg/dL (8.3 mmol/L) during the first 28 days of life, a gestational age (GA) &lt;32 weeks, and/or a birth weight &lt;1,500 g and longitudinal data on growth, metabolic health, or neurodevelopment outcomes. The GRADE system was used to assess quality of evidence. <b><i>Results:</i></b> Eight studies (<i>n</i> = 987 infants) reported long-term outcomes from 4-month corrected GA to 7 years old. Most studies compared long-term outcomes of preterm infants with and without hyperglycemia. Two studies addressed outcomes related to interventions following early hyperglycemia. Some studies found differences in growth, metabolic health, and neurodevelopment outcomes between VLBW preterm infants with hyperglycemia and without hyperglycemia, while other studies found no differences between groups. The overall graded quality of evidence was low. <b><i>Conclusions:</i></b> Well-designed randomized controlled and prospective studies are necessary to determine the effect of early hyperglycemia and its treatment on later metabolic and neurodevelopmental outcomes in VLBW infants. Authors propose a potential study design for standardizing the assessment of long-term metabolic and neurodevelopmental outcomes following early hyperglycemia in preterm infants.
DOI: 10.6084/m9.figshare.22226182.v1
title: Supplementary Material for: Genetic and environmental factors underlying parallel changes in body mass index and alcohol consumption: a 36-year longitudinal study of adult twins

description: Introduction: While the genetic and environmental underpinnings of body weight and alcohol use are fairly well-known, determinants of simultaneous changes in these traits are still poorly known. We sought to quantify the environmental and genetic components underlying parallel changes in weight and alcohol consumption, and to investigate potential covariation between them. Methods: The analysis comprised 4461 adult participants (58% women) from the Finnish Twin Cohort with four measures of alcohol consumption and body mass index (BMI) over a 36-year follow-up. Trajectories of each trait were described by growth factors, defined as intercepts (i.e., baseline) and slopes (i.e., change over follow-up), using Latent Growth Curve Modeling. Growth values were used for male (190 monozygotic pairs, 293 dizygotic pairs) and female (316 monozygotic pairs, 487 dizygotic pairs) same-sex complete twin pairs in multivariate twin modeling. The variances and covariances of growth factors were then decomposed into genetic and environmental components. Results: The baseline heritabilities were similar in men (BMI: h2=79% [95% Confidence Interval: 74,83]; alcohol consumption: h2=49% [32,67]) and women (h2=77% [73,81]; h2=45% [29,61]). Heritabilities of BMI change were similar in men (h2=52% [42,61]) and women (h2=57% [50,63]), but the heritability of change in alcohol consumption was significantly higher (p=0.03) in men (h2=45% [34,54]) than in women (h2=31% [22,38]). Significant additive genetic correlations between BMI at baseline and change in alcohol consumption were observed in both men (rA =-0.17 [-0.29,-0.04]) and women (rA=-0.18 [-0.31,-0.06]). Non-shared environmental factors affecting changes in alcohol consumption and BMI were correlated in men (rE=0.18 [0.06,0.30]). Among women, non-shared environmental factors affecting baseline alcohol consumption and the change in BMI were inversely correlated (rE=-0.11 [-0.20, -0.01]). Conclusions: Based on genetic correlations, genetic variation underlying BMI may affect change in alcohol consumption. Independent of genetic effects, change in BMI correlates with change in alcohol consumption in men, suggesting direct effects between them.
DOI: 10.6084/m9.figshare.3827610.v1
title: rbcL_all_Jan2016_full_headers.csv

description: Reference library of rbcL sequences, downloaded from the NCBI database on January 27, 2016, in CSV format, including information on GID, accession number, species, and sequence length.
DOI: 10.6084/m9.figshare.19644631.v1
title: Direct Numerical Simulation of a Moist Cough Flow using Eulerian Approximation for Liquid Droplets

description: The COVID-19 pandemic has inspired several studies on the fluid dynamics of respiratory events. Here, we propose a computational approach in which respiratory droplets are coarse-grained into an Eulerian liquid field advected by the fluid streamlines. A direct numerical simulation is carried out for a moist cough using a closure model for space-time dependence of the evaporation time scale. Stokes-number estimates are provided, for the initial droplet size of 10 μm, which are found to be ≪1, thereby justifying the neglect of droplet inertia, over the duration of the simulation. Several important features of the moist-cough flow reported in the literature using Lagrangian tracking methods have been accurately captured using our scheme. Some new results are presented, including the evaporation time for a ‘mild’ cough, a saturation-temperature diagram and a favourable correlation between the vorticity and liquid fields. The present approach can be extended for studying the long-range transmission of virus-laden droplets.
DOI: 10.6084/m9.figshare.28016804.v1
title: Expression data and differential expression analysis of <i>CDS2 </i>targeted SW837 and OMM2.5 xenografted cells

description: Expression assessment was done using Kallisto v0.51.1[PMID: 27043002] with ENSEMBLv103 annotation of the Human genome and differential expression analyses was perfomred using R4.4.1 and sleuth v0.30.1 [PMID: 28581496].This dataset contains two different folders :<b>1) kallisto:</b> contains a subfolder per sample with the results of the transcript quantifications perfomed with kallisto<b>2) expression_analysis</b>: contains three subfolders:<b>2.1) </b><b>cohort_tables:</b> with collated counts and TPM tables<b>2.2.) DE_results:</b> results from the differential expression analyses made with sleuth with respective .Rds files per comparison <b>2.3) overall_qc_figures:</b> qc plots
DOI: 10.6084/m9.figshare.23536248.v1
title: Apatite fission track (AFT) age, apatite (U/Th)-He (AHe) age and thermal modelling data for igneous bedrocks of the Wrangellia terrane on Vancouver Island, Canada

description: This file provides the detailed thermochronology ages and thermal modelling results for the manuscript - <em>Exhumation of Wrangellia on Vancouver Island, Canada during accretion processes as constrained by Low-Temperature Thermochronology</em>. Table S1. Apatite (U-Th)/He data. Dataset S1. Bedrock AFT data (Tables S2 to S13) Dataset S2. QTQt models for bedrock samples (Figures S1 to S12)
DOI: 10.6084/m9.figshare.27396006.v1
title: Revisiting the Collatz Conjecture: The Number 1 as a Masked 3

description: The Collatz conjecture, often referred to as the "3n + 1 problem," represents one of the most intriguing open questions in mathematics. It posits that the iterative application of a specific transformation on any natural number inevitably leads to the number 1. This paper presents an extraordinary discovery: the prime number 3 plays a pivotal role in the structure of the Collatz sequence by being symbolically represented as "1" through a unique transformation. During the analysis of the Collatz sequence, it was found that the prime number 3, when divided by itself, is symbolically represented as "1" without actually equating to the value 1 in the conventional numeric sense. This transformation allows 3 to assume an apparent terminal position, similar to the actual number 1, suggesting a possible hidden mathematical symmetry. This unique property is only applicable to the prime number 3 and remains unattainable for other primes and numbers in general, implying that 3 acts as a "fixed point" or "masked 3."

The following transformations summarize this process:

T(n) = \begin{cases} \frac{n}{2}, & \text{if } n \text{ is even}, \ 3n + 1, & \text{if } n \text{ is odd}. \end{cases}

When n = 3, the symbolic self-division yields:

T(3) → 1 (symbolically as masked 3).

This insight opens new questions regarding the significance of the number 3 in the Collatz sequence and posits the hypothesis that the Collatz sequence conceals a deeper mathematical structure. The symbolic reduction of 3 to 1 through self-division may play a significant role and could potentially be the key to a complete explanation of the Collatz conjecture. Therefore, we propose that the scientific community further investigates the symbolic meaning of the "masked 3" to understand why and how the number 3 assumes this unique role. This inquiry could lead to new insights into the nature of iterative processes and the role of prime numbers within these systems.
DOI: 10.17632/fff64w3rzn
title: Dataset of NaTech events triggered by lightning within the Process Industry

description: This study delves into the impactful realm of lightning strikes, a meteorological phenomenon that poses substantial risks to the process industry by potentially triggering technological disruptions. Despite constituting merely 13% of NaTech (Natural-Technological) events, lightning events hold significant consequences within the process industry. To better comprehend this, a meticulous analysis of past lightning-triggered events was conducted, utilizing open-source industrial-accident databases to create a new dataset. The research builds upon prior studies concerning NaTech events triggered by lightning and updates the information, encompassing events until the close of 2022. A systematic classification system was introduced, in adherence to NaTech risk field recent studies, enhancing the accuracy of information. Moreover, adjustments were made in compliance with international regulations governing lightning strikes. From deep analysis of past events collected in this new dataset, the variables relationship can be elucidated allowing the estimation of conditional probabilities governing critical dependencies associated with the industrial infrastructure, such as the source and the state of damage, the final scenario, and the sensible equipment or macro-sector bolster industrial vulnerability awareness against this common natural factor. Novel insights in this line could be deepened in a contribution submitted to the Heliyon Journal part of Elsevier’s Cell Press entitled.
DOI: 10.6084/m9.figshare.26046145.v1
title: Data Base

description: The purpose of this study is to evaluate changes in cardiovascular parameters during general anesthesia in patients undergoing laparoscopic cholecystectomy. Data from 342 patients with cholecystectomies for cholelithiasis at Railway Hospital Galati, Romania were reviewed retrospectively. All patients received the same type of intraoperative anesthetics. Among 342 patients, 85.7% (n =292) were female. More than half of them, 53.51% (n=183) were between 40-59 age, and only 16.37% (n =56) under 40 ages. Patients with a normal body mass index represented 45,6% (n =156), 33,3% (n =114) were underweight and 12% (n =42) had grade 1 obesity (body mass index 25 -29,9 kg/m2). Minimum intraoperative blood pressure was correlated with gender (p 0.015 &lt; 0.005), with men having higher blood pressure than women (p 0.006 &lt; 0.05) and with body mass index, high BMI is associated with elevated blood pressure (p 0.025 &lt; 0.05). Older age was correlated with increased maximum intraoperative blood pressure (p &lt; 0.001 &lt; 0.05) and, respectively, maximum intraoperative heart rate (p 0,015 &lt; 0,05). These patients have the highest risk of hemodynamic compromise that can be associated with increased ischemic heart risk.
DOI: 10.17632/crgbbpjmpc
title: Sterling Silver Spin ring Wholesaler | Anxiety Spinner Ring

description: Spin rings, also known as fidget rings or anxiety rings, are designed to help alleviate anxiety and provide a calming effect by keeping the hands occupied with a repetitive motion. They typically consist of a band with an outer ring that spins around the inner band.
Spinner rings can be helpful for individuals with anxiety, ADHD, or other conditions that cause restlessness or a need for constant movement. The repetitive motion of spinning the outer ring can provide a soothing sensation and help to redirect nervous energy.
https://www.925silvershine.com/meditation/spin-ring