cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5286/isis.e.rb2220225
title: Separate incoherent and coherent QENS of protonated and fully deuterated GFP with polarisation analysis.

description: In order to detect quantum effects in the individual dynamics of hydrogens in proteins, we study a fully deuterated protein powder (dGFP) compared to a protonated one (pGFP) both hydrated in D2O, to search for mass effects. We performed QENS at ILL on a TOF spectrometer (IN5) in 2019. However, it is obvious from experimental data that coherent scattering stemming from collective dynamics of all atoms, including the water hydration shell, contaminates the signal arising from incoherent scattering. It was confirmed through static polarisation analysis at 300K on D7 instrument at ILL in 2021, and proved to be highly dependent on the momentum transfer Q and the temperature probed. In order to yield rigorously comparable results, we want to separate both contributions to QENS at sub-meV resolution by performing polarisation analysis on LET instrument for a large Q range at 10, 220 and 310K.
DOI: 10.5286/isis.e.rb2220260
title: Probing the interfacial magnetism of Antiferromagnetic insulators

description: This project has a chance of unambiguously demonstrating spin-orbit torque induced switching for a typical perpendicular antiferromagnetic (AFM) material whose structure is simple and colinear. This experiment not only confirms the feasibility of using SOT to control magnetism of AFM but also clearly rules out other thermal artefacts by high Rxy signal-to-noise ratio and the typical SOT behaviors under external fields. This experiment can advance the development of antiferromagnetic spintronics and memory devices.
DOI: 10.5286/isis.e.rb2220260-1
title: Probing the interfacial magnetism of Antiferromagnetic insulators

description: This project has a chance of unambiguously demonstrating spin-orbit torque induced switching for a typical perpendicular antiferromagnetic (AFM) material whose structure is simple and colinear. This experiment not only confirms the feasibility of using SOT to control magnetism of AFM but also clearly rules out other thermal artefacts by high Rxy signal-to-noise ratio and the typical SOT behaviors under external fields. This experiment can advance the development of antiferromagnetic spintronics and memory devices.
DOI: 10.3535/5ch-fzn-38z
title: Valerianella vesicaria (L.) Moench

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/6ad-yn3-ena
title: Hordeum murinum subsp. murinum

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.5286/isis.e.rb2220033
title: Chemcial and thermal effects of curvature at oil-water interfaces

description: Despite the obvious importance, understanding about effects of surfactant structure and temperature (T) at oil-water (O-W) interfaces is needed. This proposal aims to explore these effects with a range of novel, custom-made and structurally diverse surfactants (Figure 1). Of particular focus is the chemical identity of the surfactant hydrophobic chain tip termini, which are in direct contact with the molecules of the external oil phase. With these surfactants, the hydrophilic group structure remains constant (sodium sulfosuccinate), thereby permitting effects of T on hydrophobic interactions (surfactant-oil) to be isolated.
DOI: 10.5286/isis.e.rb2220033-2
title: Chemcial and thermal effects of curvature at oil-water interfaces

description: Despite the obvious importance, understanding about effects of surfactant structure and temperature (T) at oil-water (O-W) interfaces is needed. This proposal aims to explore these effects with a range of novel, custom-made and structurally diverse surfactants (Figure 1). Of particular focus is the chemical identity of the surfactant hydrophobic chain tip termini, which are in direct contact with the molecules of the external oil phase. With these surfactants, the hydrophilic group structure remains constant (sodium sulfosuccinate), thereby permitting effects of T on hydrophobic interactions (surfactant-oil) to be isolated.
DOI: 10.5286/isis.e.rb2255008-1
title: Commerical Access to SANS2D
DOI: 10.3535/xs4-p5e-rt9
title: Scandix pecten-veneris L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/zjd-2qj-fzw
title: Plantago cretica L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.5286/isis.e.rb2220792
title: NR Study of Helper Lipid Effect on Interaction between Lipid Nanoparticles and a Model Lipid Bilayer Mimicking Endosome Membrane

description: LNP has become one of the hottest topics during the ongoing pandemic of COVID-19 due to their application as the gene delivery vector for both the Pfizer–BioNTech and Moderna mRNA vaccines. LNPs are internalised by the cells through endocytosis and the endosomal escape process releases the payloads: this process is often the major bottleneck in achieving high cell transfections. Neutron reflection is particularly powerful to study the interaction between the LNPs and a model supported lipid bilayer (SLB) mimicking an endosome membrane. The aim of this study is to determine how different lipids help mediate the interaction of LNPs with lipid membrane bilayer, mimicking an important step in endocytosis, as a function of crucial factors such as temperature and solution pH.
DOI: 10.5286/isis.e.rb2220792-2
title: NR Study of Helper Lipid Effect on Interaction between Lipid Nanoparticles and a Model Lipid Bilayer Mimicking Endosome Membrane

description: LNP has become one of the hottest topics during the ongoing pandemic of COVID-19 due to their application as the gene delivery vector for both the Pfizer–BioNTech and Moderna mRNA vaccines. LNPs are internalised by the cells through endocytosis and the endosomal escape process releases the payloads: this process is often the major bottleneck in achieving high cell transfections. Neutron reflection is particularly powerful to study the interaction between the LNPs and a model supported lipid bilayer (SLB) mimicking an endosome membrane. The aim of this study is to determine how different lipids help mediate the interaction of LNPs with lipid membrane bilayer, mimicking an important step in endocytosis, as a function of crucial factors such as temperature and solution pH.
DOI: 10.5286/isis.e.rb2255008
title: Commerical Access to SANS2D
DOI: 10.3535/9ax-w9p-rtw
title: Hypericum montanum L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.5286/isis.e.rb2220200
title: NR determination of the structural profile of asymmetric myelin membranes and their interaction mechanism with Myelin Basic Protein (MBP)

description: Myelin is an asymmetric multilamellar membrane wrapped around the axons and consists of alternating extracellular and cytoplasmic leaflets. Any structural changes of the myelin sheath, mainly demyelination, are signatures of several inflammatory neurological disorders as Multiple Sclerosis (MS). We suggest generating flat asymmetric myelin membranes with intercalated MBP, which are suitable for Neutron Reflectometry (NR) analysis. We aim to obtain a precise measurement of the vertical membrane layer structure for both native and EAE (an accepted animal model for MS) compositions. From the differences between them important clues on the underlying biological processes of MS can be inferred. We also propose to carry do time-resolved NR to study the stability of the asymmetric membranes by assessing the flip-flop time scales.
DOI: 10.5286/isis.e.rb2220200-1
title: NR determination of the structural profile of asymmetric myelin membranes and their interaction mechanism with Myelin Basic Protein (MBP)

description: Myelin is an asymmetric multilamellar membrane wrapped around the axons and consists of alternating extracellular and cytoplasmic leaflets. Any structural changes of the myelin sheath, mainly demyelination, are signatures of several inflammatory neurological disorders as Multiple Sclerosis (MS). We suggest generating flat asymmetric myelin membranes with intercalated MBP, which are suitable for Neutron Reflectometry (NR) analysis. We aim to obtain a precise measurement of the vertical membrane layer structure for both native and EAE (an accepted animal model for MS) compositions. From the differences between them important clues on the underlying biological processes of MS can be inferred. We also propose to carry do time-resolved NR to study the stability of the asymmetric membranes by assessing the flip-flop time scales.
DOI: 10.3535/gm1-44q-t9v
title: Sparganium erectum subsp. neglectum (Beeby) K.Richt.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/q28-zlg-mfz
title: Bromus inermis Leyss.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.5286/isis.e.rb2210330-3
title: Studying the heterogeneity of crosslinked polymer networks

description: Thin polymer coatings are important as they protect vital metal infrastructure (bridges, buildings, boats and planes) that would otherwise rust/corrode. The majority of these are based on epoxy oligomers that are crosslinked via a curing reaction to form a continuous insoluble polymer network. The misconception that no water at all is able to permeate these polymer coating means that we must adjust how we think about these coatings. We know from polymer physics that the energy penalty driving phase separation scales with polymerization index N. In these polymer networks we suspect that phase separation is important in determining the properties of diffusion, percolation and uptake of water in these layers. In this proposal we plan to use deuterated DGEBA and SANS to study where the water is localised in these polymer networks and understand the length scale of phase separation.
DOI: 10.5286/isis.e.rb2220190
title: Investigating the accessibility of pore structures for alkane isomerisation

description: The isomerisation of n-butane is the main route to isobutane, a market valued at $20 billion, due to isobutanes use as a fuel additive, propellant and precursor for tert-butyl hydroperoxide. Zeolite catalysts are suited to this reaction because their micropores offer a confined space to control the reaction pathway and prevent bulky side products forming. However, it is important to understand the accessibility of these porous, as this strongly influences reaction conversion. Therefore, we propose to contrast how n-butane occupies different zeotype frameworks with different porosities, but identical active sites. Thus, allowing us to focus purely on the accessibility of the framework, to explain the significant differences in catalytic activity. We will investigate the occupation of non-deuterated and fully deuterated n-butane through the internal pores of CoAlPO-5 and CoAlPO-18.
DOI: 10.5286/isis.e.rb2220190-1
title: Investigating the accessibility of pore structures for alkane isomerisation

description: The isomerisation of n-butane is the main route to isobutane, a market valued at $20 billion, due to isobutanes use as a fuel additive, propellant and precursor for tert-butyl hydroperoxide. Zeolite catalysts are suited to this reaction because their micropores offer a confined space to control the reaction pathway and prevent bulky side products forming. However, it is important to understand the accessibility of these porous, as this strongly influences reaction conversion. Therefore, we propose to contrast how n-butane occupies different zeotype frameworks with different porosities, but identical active sites. Thus, allowing us to focus purely on the accessibility of the framework, to explain the significant differences in catalytic activity. We will investigate the occupation of non-deuterated and fully deuterated n-butane through the internal pores of CoAlPO-5 and CoAlPO-18.
DOI: 10.3535/1z3-zk1-jvw
title: Roemeria hybrida (L.) DC.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/35e-ssm-8g3
title: Onobrychis squarrosa Viv.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.5286/isis.e.rb2220244-1
title: Unlocking the potential of solid-state batteries through in-situ battery analysis using X-ray tomography and neutron imaging

description: To reduce global warming, rechargeable batteries are one of the key technologies to increase the use of electric transportation and storage of electricity from intermittent renewable sources. Current Li ion batteries have safety hazards and limited energy density. Solid-state Li metal batteries (SSLMBs) are a new type of batteries that can improve safety and energy density, but the brittleness of the solid state electrolyte (SSE) materials leads to cracking during expansion and shrinkage when the SSLMBs are being charged and discharged. This experiment uses neutron imaging to investigate the distribution of Li ions and X-ray computed tomography to investigate microstructure changes of SSE. The research objective is to improve cycling stability of the SSLMBs during Li intercalation and removal.
DOI: 10.5286/isis.e.rb2291029
title: Proprietary access for Johnson Matthey
DOI: 10.5286/isis.e.rb2291029-1
title: Proprietary access for Johnson Matthey
DOI: 10.3535/9dq-3l1-gbc
title: Medicago polymorpha L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/en0-4j0-sqt
title: Alopecurus cucullatus (L.) Raspail

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.5286/isis.e.rb2220244
title: Unlocking the potential of solid-state batteries through in-situ battery analysis using X-ray tomography and neutron imaging

description: To reduce global warming, rechargeable batteries are one of the key technologies to increase the use of electric transportation and storage of electricity from intermittent renewable sources. Current Li ion batteries have safety hazards and limited energy density. Solid-state Li metal batteries (SSLMBs) are a new type of batteries that can improve safety and energy density, but the brittleness of the solid state electrolyte (SSE) materials leads to cracking during expansion and shrinkage when the SSLMBs are being charged and discharged. This experiment uses neutron imaging to investigate the distribution of Li ions and X-ray computed tomography to investigate microstructure changes of SSE. The research objective is to improve cycling stability of the SSLMBs during Li intercalation and removal.
DOI: 10.5286/isis.e.rb2220482
title: Oxidation of a natural organic matter at air-mineral interface by aqueous ozone II

description: Following a successful, one-day, proof-of-concept experiment to characterize the system, we request time for an ISIS/RHUL facility development PhD student: Humic material silanized onto silica blocks will be oxidised at the water-mineral interface using aqueous ozone. The kinetics of the reaction are critical in the assessment of the atmospheric lifetime of HUmic-Like Substances (HULIS) being cloud-processed on atmospheric mineral aerosol. Film thickness measurements will allow radiative-transfer assessment of top-of-atmosphere heating to be calculated for cloud processing. The experiments will incorporate a new fibre-optic launched UV-Vis solid-liquid cell to measure the concentration of oxidant within the cell. The experiment is for a NERC grant joint between ISIS and RHUL. The proof-of-concept demonstrated we can make the films and now we ask for time to perform the original proposal
DOI: 10.5286/isis.e.rb2220482-1
title: Oxidation of a natural organic matter at air-mineral interface by aqueous ozone II

description: Following a successful, one-day, proof-of-concept experiment to characterize the system, we request time for an ISIS/RHUL facility development PhD student: Humic material silanized onto silica blocks will be oxidised at the water-mineral interface using aqueous ozone. The kinetics of the reaction are critical in the assessment of the atmospheric lifetime of HUmic-Like Substances (HULIS) being cloud-processed on atmospheric mineral aerosol. Film thickness measurements will allow radiative-transfer assessment of top-of-atmosphere heating to be calculated for cloud processing. The experiments will incorporate a new fibre-optic launched UV-Vis solid-liquid cell to measure the concentration of oxidant within the cell. The experiment is for a NERC grant joint between ISIS and RHUL. The proof-of-concept demonstrated we can make the films and now we ask for time to perform the original proposal
DOI: 10.3535/93f-1r7-3q6
title: Lysimachia arvensis subsp. arvensis

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/q46-43t-m4c
title: Scandix iberica M. Bieb.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.5286/isis.e.rb2220159
title: Lipid exchange for ApoA-I-based reconstituted (r-) HDL, compositional effects

description: Lipoprotein function is to carry fats in our body. HDL is able to remove cholesterol thanks to reverse cholesterol transport which requires enzymes and receptors to work. HDL is also able to exchange lipids to a greater extent than LDL in a receptor free mode. Not all HDL exchanges lipids to the same extent. The capacity of HDL to exchange lipids depends on the apolipoprotein content and probably also on the lipid cargo. In this proposal we aim at quantifying HDL capacity to exchange lipids as a function of apolipoprotein type (ApoA-I and a single amino acid mutant that is pathogenic) and lipid cargo (saturated vs unsaturated lipids) usign neutron reflection. The data will clarify the observed effects we see in HDL extracted from adult human male blood. This data is very important to understand the function of HDL and designed therapeutics against atherosclerosis.
DOI: 10.5286/isis.e.rb2220159-1
title: Lipid exchange for ApoA-I-based reconstituted (r-) HDL, compositional effects

description: Lipoprotein function is to carry fats in our body. HDL is able to remove cholesterol thanks to reverse cholesterol transport which requires enzymes and receptors to work. HDL is also able to exchange lipids to a greater extent than LDL in a receptor free mode. Not all HDL exchanges lipids to the same extent. The capacity of HDL to exchange lipids depends on the apolipoprotein content and probably also on the lipid cargo. In this proposal we aim at quantifying HDL capacity to exchange lipids as a function of apolipoprotein type (ApoA-I and a single amino acid mutant that is pathogenic) and lipid cargo (saturated vs unsaturated lipids) usign neutron reflection. The data will clarify the observed effects we see in HDL extracted from adult human male blood. This data is very important to understand the function of HDL and designed therapeutics against atherosclerosis.
DOI: 10.3535/m81-wtp-3k2
title: Scandix stellata Banks & Sol.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/qn2-fbt-0rj
title: Gypsophila vaccaria (L.) Sm.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.5286/isis.e.rb2200036-1
title: Uncovering magnetic structures underneath giant spontaneous exchange bias effect in a kagome magnet

description: The exchange bias (EB) effect,characterized by a shift of the hysteresis loop,plays a key role in spintronics and magnetic recording. The mechanism of EB effect is still lacking, what we know isthat EB effect originates from the pinned uncompensated magnetic moments. Recently, reports show EB effect is observed in single-phase materials which origin from multiple magneticbehaviors, e.g. AFM/FM, spin glass/FM, and spin glass/AFM. And These single-phase materials are also more appropriate as prototypes to understand the mechanism of EB effect usingtechniques which are difficult to apply on heterostructures like neutron diffraction. The hexagram-like kagome lattice, a “functional group” with giant geometrical frustration, exhibits diversemagnetic behaviors. Utilizing kagome lattice, we design a giant spontaneous EB effect in TbMn6(Ge, Ga)6 as large as 1.25 T at 5 K.
DOI: 10.5286/isis.e.rb2220185
title: Magnetic structure of a Pr-based antiferromagnet with competing interactions

description: Rare-earth based correlated materials often host competing interactions and electronic ground states associated with different degrees of freedom. We have examined a Pr-based antiferromagnet which has competing antiferromagnetic and ferromagnetic interactions. We find that applying hydrostatic pressure induces a new low-temperature first-order transition, and it is of particular interest to determine its nature, and whether it corresponds to nematic ordering. In order to understand the electronic ground state and magnetism of the system, we propose to perform neutron diffraction on both powder and single crystal samples using the WISH diffractometer, so as to determine the detailed magnetic structure and the temperature dependence of the order parameter. Knowing whether the magnetic order breaks the lattice rotational symmetry will be important for uncovering possible nematicity.
DOI: 10.5286/isis.e.rb2220185-1
title: Magnetic structure of a Pr-based antiferromagnet with competing interactions

description: Rare-earth based correlated materials often host competing interactions and electronic ground states associated with different degrees of freedom. We have examined a Pr-based antiferromagnet which has competing antiferromagnetic and ferromagnetic interactions. We find that applying hydrostatic pressure induces a new low-temperature first-order transition, and it is of particular interest to determine its nature, and whether it corresponds to nematic ordering. In order to understand the electronic ground state and magnetism of the system, we propose to perform neutron diffraction on both powder and single crystal samples using the WISH diffractometer, so as to determine the detailed magnetic structure and the temperature dependence of the order parameter. Knowing whether the magnetic order breaks the lattice rotational symmetry will be important for uncovering possible nematicity.
DOI: 10.15468/dl.v8q2e8
title: Occurrence Download

description: A dataset containing 544 species occurrences available in GBIF matching the query:
{
 "DatasetKey" : [
 "is Vascular plants from a study of primary producer traits across an altitudinal gradient in alpine Finse"
 ]
}

 The dataset includes 544 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0109219-250525065834625/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.3535/dt8-06a-6vw
title: Medicago polymorpha L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.