cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17632/m7r4msjb4c
title: A compendium of mutational signatures of environmental agents Kucab et al.

description: Whole-genome-sequencing (WGS) of human tumours has revealed distinct mutation patterns that hint at the causative origins of cancer. We examined mutational signatures in 324 WGS human induced pluripotent stem cells exposed to 79 known or suspected environmental carcinogens. 41 yielded characteristic substitution mutational signatures. Some were similar to signatures found in human tumours. Additionally, 6 agents produced double-substitution signatures and 8 produced indel signatures. Investigating mutation asymmetries across genome topography revealed fully functional mismatch and transcription-coupled repair pathways. DNA damage induced by environmental mutagens can be resolved by disparate repair/replicative pathways, resulting in an assortment of signature outcomes even for a single agent. This compendium of experimentally-induced mutational signatures permits further exploration of roles of environmental agents in cancer aetiology, and underscores how human stem cell DNA is directly vulnerable to environmental agents.
DOI: 10.17632/4mc5hgr2fg
title: The Holstein colostrum proteome.

description: Proteomic profile of colostrum collected from Holstein primiparous cows
DOI: 10.17632/ncpwm55snp
title: Replication of the paper "Measuring Access and Inequality of Access to Health Care: A Decomposition Approach"

description: This folder contains the Stata do-files and data used to replicate the results presented in the scientific publication titled Measuring Access and Inequality of Access to Health Care: A Decomposition Approach. 
The do-files are designed to import data, compute various indices related to access to healthcare, perform factor decomposition, generate figures, and conduct inequality decomposition.
DOI: 10.6084/m9.figshare.23951592.v1
title: Dataset

description: To develop a prognostic model for neoadjuvant immunochemotherapy efficacy in esophageal squamous cell carcinoma (ESCC) by analyzing the immune microenvironment
DOI: 10.17632/j8bw86mc5h
title: A gut microbiota-associated hepatic c-kit+ type 1 classical dendritic cell subset: a pivotal contributor to the pathogenesis of metabolic dysfunction-associated steatohepatitis (MASH)

description: The fecal microbiome data of "A gut microbiota-associated hepatic c-kit+ type 1 classical dendritic cell subset: a pivotal contributor to the pathogenesis of metabolic dysfunction-associated steatohepatitis (MASH)" Nature Communication (2024).
DOI: 10.6084/m9.figshare.24137925.v1
title: Dataset of 50 prostate slides

description: Dataset of 50 prostate slides for the paper entitled "Semantic segmentation of gleason patterns in prostate adenocarcinoma exploiting an ensemble model of attention-based U-Net"
DOI: 10.6084/m9.figshare.14270746.v1
title: Use of near infrared spectroscopy in cotton seeds physiological quality evaluation

description: Abstract: This study aimed to evaluate the near-infrared spectroscopy potential in analyzing the quality of cottonseed regarding different physiological quality levels, noting the need for faster techniques and tools to aid decision making. It was used eight samples of cottonseed with and without lint, presenting different physiological quality. The “high” (lots 1, 4, 5, 6 and 7) and “low” (lots 2, 3 and 8) vigor levels were defined based on vigor tests carried out and on the Normative Instruction 45/2013. The near infrared spectroscopy spectra was obtained from four types of sample preparations: whole seeds, cut in a half, without tegument and grounded seeds. Using the spectra and the grouping of lots in high and low vigor, cross validation models were optimized, built using the PLS - DA method, making it possible to predict seed classes. Grounded seeds were the best type of sample preparation, with 95% of correct predictions for high vigor seeds and 100% of low vigor (both for seeds with lint) and with 100% correct predictions for high vigor seeds and 91.7% low vigor (without lint).
DOI: 10.6084/m9.figshare.16855612.v1
title: Supplementary Material for: Associations of Body Mass Index-Metabolic Phenotypes with Cognitive Decline in Parkinson’s Disease

description: <b><i>Background:</i></b> Growing evidence suggests important effects of body mass index (BMI) and metabolic status on neurodegenerative diseases. However, the roles of BMI and metabolic status on cognitive outcomes in Parkinson’s disease (PD) may vary and are yet to be determined. <b><i>Methods:</i></b> In total, 139 PD patients from the whole PD cohort in Parkinson’s Progression Markers Initiative database underwent complete laboratory measurements, demographic and anthropometric parameters at baseline, and were enrolled in this study. Further, they were categorized into 4 different BMI-metabolic status phenotypes using Adult Treatment Panel-III criteria. Motor and cognition scales at baseline and longitudinal changes after a 48-month follow-up were compared among the 4 groups. Repeated-measure linear mixed models were performed to compare PD-related biomarkers among BMI-metabolic status phenotypes across time. <b><i>Results:</i></b> We found that PD patients in the metabolically unhealthy normal weight group showed more cognitive decline in global cognition and visuospatial perception after a 48-month follow-up than those in the other 3 groups (<i>p</i> &lt; 0.05). No difference was found in motor scales among different BMI-metabolic status phenotypes. Finally, compared to the metabolically healthy normal weight group, the metabolically healthy obesity group had lower CSF Aβ42 and serum neurofilament levels in repeated-measure linear mixed models adjusting for age, gender, APOE e4 carrier status, and years of education (<i>p</i> = 0.031 and 0.046, respectively). <b><i>Conclusion:</i></b> The MUNW phenotype was associated with a rapid cognitive decline in PD.
DOI: 10.17632/h8gwx4r2bn
title: A comprehensive parcel-level dataset on Farmland Assessment Act in Salt Lake County, Utah

description: The dataset compiles important factors influencing farmland conversion in Salt Lake County, Utah, from 2010 to 2018. Collected from secondary sources, the data is processed at the parcel level. Parcel boundary information, including location, greenbelt status, and ownership details are sourced from the Salt Lake County Assessor’s Office. It incorporates determinants and control variables from the USDA National Agricultural Statistics Service’s Cropland Data Layers and NASA’s MODIS-EVI datasets. This dataset is valuable for researchers, educators, and practitioners in sustainable development, environmental studies, and social sciences with a focus on US farmland preservation. The dataset can be used to test hypotheses on the control of urban growth, study the impact of preferential farmland tax assessment programs, and compare farmland tax policies across the US. Additionally, the dataset supports trend generation, summative analyses, and integration with other geospatial data to explore indirect impacts on ecosystem services. Its simple format makes the dataset an excellent teaching tool for statistics or econometrics classes.
DOI: 10.17632/sp25w5kxvd
title: Miyazaki et al., iScience, 2022

description: Raw data for Miyazaki et al., "Intracellular Ca2+ dynamics in the ALA neuron reflect sleep pressure and regulate sleep in Caenorhabditis elegans" published in iScience (2022).
DOI:https://doi.org/10.1016/j.isci.2022.104452
DOI: 10.17632/yx22hyw853
title: Topology optimization of MBB and a Simplified Side Impact Problem using a Spatial kernel

description: These are the computer models used for structural topology optimization from the paper "A spatial kernel approach for topology optimization" by Roux, Yi, and Gandikota.
DOI: 10.17632/8nk3scf9bj
title: Supplemental materials: Modeling the relationship between heat stress, feed intake and day relative to calving in non-lactating dairy cows

description: Supplemental materials of the manuscript "Modeling the relationship between heat stress, feed intake and day relative to calving in non-lactating dairy cows".
DOI: 10.17632/g4674nx62z
title: Data for: Robust and Rapid Superlubrication Obtained with Mixtures of Hydrated Ions and Polyethylene Glycol Solutions

description: The Origin files of research data, and Matlab code.
DOI: 10.17632/5zrtmp7gwd
title: Electric Vehicle Charging Dataset

description: This electric vehicle (EV) charging dataset includes the EV connection time, charging duration, energy consumption, and day number each corresponding respectively to connectionTime_decimal, chargingDuration, kWhDelivered, dayIndicator columns in the dataset for an EV charging parking lot. The data is generated using conditional tabular generative adversarial networks (CTGAN) and kernel density estimation (KDE) from the Caltech dataset to maintain a realistic load profile, accurately model EV owner behaviors, and preserve the relationship between the columns of the dataset. This dataset includes EV data for 29,600 days while the original Caltech dataset includes data for only 185 days. This data can be useful in training machine learning algorithms, specifically, reinforcement learning algorithms. The connection time range is 0-24. The unit for charging duration is hour and energy consumption is in kWh.
DOI: 10.6084/m9.figshare.14038832.v2
title: Table 3. Modified PRISMA-ScR checklist

description: Table 3. Modified PRISMA-ScR checklist
DOI: 10.17632/vgd2hxjs86
title: Placebo group regrowth rate in alopecia areata clinical trials: Supplementary Materials

description: Placebo group regrowth rate in alopecia areata clinical trials: A systematic review and meta-analysis.
Supplementary materials.
DOI: 10.17632/zjwhhpzgvm
title: Phosphate Depletion in Insulin-Insensitive Skeletal Muscle Drives AMPD Activation and Sarcopenia in Chronic Kidney DIsease

description: The original images and blots of the manuscript Phosphate Depletion in Insulin-Insensitive Skeletal Muscle Drives AMPD Activation and Sarcopenia in Chronic Kidney DIsease
DOI: 10.6084/m9.figshare.25217198.v1
title: Supplementary Material for: Eosinophils are an endogenous source of IL-4 during filarial infections and contribute to the development of an optimal T helper 2 response

description: Interleukin-4 (IL-4) is a central regulator of type 2 immunity, crucial for the defense against multicellular parasites like helminths. This study focuses on its roles and cellular sources during Litomosoides sigmodontis infection, a model for human filarial infections. Our research uncovers eosinophils as a major source of IL-4, especially during the early phase of filarial infection. Using dblGATA mice lacking eosinophil and subsequently eosinophil-derived IL-4, we reveal their profound impact on the Th2 response. Lack of eosinophils impact Th2 polarization and resulted in impaired type 2 cytokine production. Surprisingly, eosinophil deficiency had no impact on macrophage polarization and proliferation as well as on antibody production. These findings shed new light on IL-4 dynamics and eosinophil effector functions in filarial infections.
DOI: 10.17632/ntdhgrbyyy
title: Cardiac rehabilitation after AMI and atherogenic miRNAs

description: Clinical, biochemical, anthropometric parameters, and microRNA data are summarized based on study follow-up time points. Raw data from qPCR is included in a separate Excel sheet.
DOI: 10.21233/z0at-v422
title: CRDY29 pollen surface sample dataset

description: Raw data for the CRDY29 pollen surface sample dataset submitted to the Neotoma Paleoecology Database. Data is available through the landing page in JSON format. The landing page referenced by the DOI also contains links to publications and a map-based viewer for the dataset. The Neotoma Paleoecology Database maintains a homepage at https://www.neotomadb.org.
DOI: 10.6084/m9.figshare.1368310.v1
title: BOLD fMRI of C-fiber mediated nociceptive processing in mouse brain in response to thermal stimulation of the forepaw

description: Functional magnetic resonance imaging (fMRI) in rodents enables non-invasive studies of brain function in response to peripheral input or at rest. In this study we describe a thermal stimulation paradigm using infrared laser diodes to apply noxious heat to the forepaw of mice in order to study nociceptive processing. Stimulation at 45 and 46 °C<br>led to robust BOLD signal changes in various brain structures including the somatosensory cortices and the thalamus. The BOLD signal amplitude scaled with the temperature applied but not with the area irradiated by the laser beam. To demonstrate the specificity of the paradigm for assessing nociceptive signaling we administered the quaternary lidocaine derivative QX-314 to the forepaws, which due to its positive charge cannot readily cross biological membranes. However, upon activation of TRPV1 channels following the administration of capsaicin the BOLD signal was largely abolished, indicative of a selective block of the C-fiber nociceptors due to QX-314 having entered the cells via the now open TRPV1 channels. This demonstrates that the cerebral BOLD response to thermal noxious paw stimulation is specifically mediated by C-fibers.
DOI: 10.17632/shm45fmjcx
title: Industrial Carbon Emission Intensity: a comprehensive dataset of European Regions

description: The dataset includes data on Carbon Emission Intensity from industrial sources for the European Regions.
DOI: 10.6084/m9.figshare.27902268.v1
title: Data supporting 'Increased crevassing across accelerating Greenland Ice Sheet margins'

description: Data supporting the paper:

Chudley, T. R., Howat, I. M., King, M. D., and MacKie, E. J. (accepted) Increased crevassing across accelerating Greenland Ice Sheet margins. Nature Geoscience.

Full details of the data are described within the README.md file.
DOI: 10.17632/24xbkgwcx7
title: Published Journal of Studies in Islam and Psychology; No. 24

description: The journal is set to publish original articles on a wide range of issues including;

 The philosophy of psychology with a critical outlook from the perspective of Islam;
 The uses of psychology in the service of the Islamic society and its needs;
 The formation of psychology in the Islamic society;
 Psychological analysis of Islamic concepts in areas such as:
 1. Anthropology, such as: banned, impatience, hasty, captious, pious, faithful;
 2. Belief, such as: God, resurrection, Imamate, intercession, Paradise, Hell and ...;
 3. Value, such as: repentance, trust, self-esteem, mental relaxation, grief, fear;
 4. Practical instructions of Islam, such as: qisas (retaliation), prayers, inheritance, hajj, khums (one fifth);
 Study of psychological findings from Islamic perspective in terms of critique, confirmation and completion, alternative presentation, presentation of new theory;
DOI: 10.17632/2htygv23m6
title: Aging-Induced Restructuring of Lamellar Morphology in Material Extrusion-Fabricated Polyhydroxyalkanoate (PHA) Composite: Dataset

description: This dataset complements the study "Aging-Induced Restructuring of Lamellar Morphology in Material Extrusion-Fabricated Polyhydroxyalkanoate (PHA) Composite: The Role of Thermal History on Mechanical Properties". It includes original mechanical testing data and the data table ready for statistical analysis in any statistical software.
DOI: 10.17632/hh42swfh9w
title: Dataset of pollination traits in Fabales

description:  This the largest morphological dataset constructed for Fabales to date, and the data presented  can be used for morphology, biogeography, ancestral state, ancestral area analyses of any Fabales clades. The dataset is related to Aygoren Uluer et al. 2022 (https://bmcecolevol.biomedcentral.com/articles/10.1186/s12862-022-02003-y)
DOI: 10.17632/nz6hrryn55
title: LINF_120016900

description: arginine N-methyltransferase-like protein; Leishmania infantum
DOI: 10.6084/m9.figshare.27287550.v1
title: AOSLO Multi-spectral AF Images

description: The retinal pigment epithelium (RPE) is vital for the healthy function of the retina. Cellular level changes in the RPE are not visualized with current clinical techniques due to a lack of spatial resolution. Fluorescence adaptive optics scanning light ophthalmoscopy (AOSLO) can image RPE cells by utilizing their intrinsic autofluorescence (AF). The RPE AF has been imaged with only a few discrete excitation and emission bands and the multi-spectral AF has not been interrogated systematically at the level of single cells. In this study, we imaged 16 healthy eyes (ages 20-75) with AOSLO to investigate the multi-spectral AF as a function of age and wavelength with excitation from 650 - 805 nm. Quantitative analysis showed that 720 nm light produced images with the highest SNR (65.0 dB). Spatial AF variability showed a trend to increase with aging, suggesting increased heterogeneity in RPE AF with age. Spatial variability in the multi-spectral fluorescence of RPE cells with age may be a consequence of normal age-related loss of RPE cells. Multi-spectral fluorescence AOSLO provides new insight into aging related changes to RPE cells and may be a useful tool for studying diseases that affect the RPE, such as age-related macular degeneration (AMD).
DOI: 10.17632/fj636xh5y6
title: Robust and prototypical immune responses towards COVID-19 vaccine in First Nations people are impacted by comorbidities. Zhang et al.

description: Supplementary Table 5 from Zhang et al., Nature Immunology, 2023
https://doi.org/10.1038/s41590-023-01508-y
DOI: 10.6084/m9.figshare.28183187.v1
title: Stage one data

description: This represents the stage one quantitative data, providing an initial analysis based on measurable variables collected during the first phase of the research. The project investigated the extent to which homework affects secondary school adolescents’ leisure. This was important because the majority of research within this area focused on the effects of homework on adolescents’ academic development. This project explored the other, non-academic effects on leisure. An interpretivist sequential mixed methods research design was used to explore the actual versus expected time spent on homework, time spent on leisure and/or non-academic responsibilities. This was achieved from the perspective of the parents, adolescents, and teachers using questionnaire in stage one and then follow-up semi-structured interviews for parents and adolescents during stage two. Three schools participated in the project, each with distinct characteristics. School one, located in the Nottingham East constituency, became an academy in 2018 and was uninspected by Ofsted. It was larger than average, with higher-than-average numbers of minority ethnic students, English as an Additional Language (EAL) learners, and those eligible for free school meals. It had a homework policy for all year groups but no specified consequences for non-completion. School two, also in Nottingham East constituency, became an academy in 2012 and was rated good by Ofsted in 2017. It had below-average numbers of minority ethnic and EAL students and average free school meal eligibility but no homework policy. School three, based in Nottingham North, joined a multi-academy trust in 2012 and was rated good by Ofsted in 2018. It was ethnically diverse, with a significant proportion of EAL learners and high free school meal eligibility. Its homework policy was similar to school one's but included detention as a consequence for non-completion.The thesis can be accessed here: Exploring the effects of homework on secondary school adolescents’ leisure - IRep - Nottingham Trent University
DOI: 10.17632/j9km43bzrs
title: Dataset for the performance of 15 lumbar movement control tests in non-specific chronic low back pain

description: Value of the Data
•	The dataset may help to better understand the complexity of LMC ability. 
•	The dataset can be processed to investigate the structure of LMC and how single test results can be combined.
•	The dataset can be used to compare the ability of LMC in participants with NSCLBP with other groups. The data of other groups or subgroups can be calibrated using the data provided with this article. 
•	The dataset will be beneficial for researchers and practitioners evaluating and measuring LMC.
Abstract
The ability to actively control movements of the lumbar spine (LMC) is believed to play an important role in non-specific chronic low back pain (NSCLBP). However, because NSCLBP is a multifactorial problem and LMC a complex ability, different aspects of LMC are still debated including the influence of pain, the question whether LMC is a cause or consequence of NSCLBP or whether differences in LMC are due to population variance. 
The complexity of LMC is reflected in the large number of described tests, hence it is not possible to evaluate LMC by a single test. LMC ability should be understood as a latent construct. The structure of LMC and how to summarize results of different single LMC tests is unknown.
The dataset provided in this article was used to analyse the structural validity of LMC in NSCLBP. 277 participants (age 42.4 years (± 15.8), 61% female) performed 15 different test movements. 21 experienced physiotherapists rated the performance of each test movement on a nominal scale (correct / incorrect including the direction of test movement). A test was rated as “incorrect” if movement in the lumbar spine occurred prematurely and / or excessively based on the visual observation of a trained physiotherapist. In addition to the judgement whether the test performance was correct / incorrect the direction of test movement and the presence of pain was noted. 
For statistical analysis, raw data was converted to a binary scale (correct / incorrect). Item response theory (IRT) is recommended to analyse the data because the underlying statistical model is reflective, the single LMC tests are binary scaled (correct / incorrect) and the underlying ability (LMC) measured on a continuous scale.
First dimensionality and local independence were analysed, followed by selection of the best fitting IRT model. Finally, IRT modelling was used to describe the psychometric properties of each item and each battery of tests. 
The datasets provided in this article are useful for calibration and for group comparisons. Besides they support a better understanding of LMC.
DOI: 10.6084/m9.figshare.1256328.v1
title: electricity types

description: electricity types
DOI: 10.17632/4wxmhr5rgs
title: Data for: Are Instructor Generated YouTube Videos Effective in Accounting Classes? A Study of Student Performance, Engagement, Motivation, and Perception

description: We examine whether instructor generated YouTube videos improve student performance in a principles of accounting class. We also gather information about student engagement, motivation, and perception. The instructor designed the videos to help students in traditional and hybrid classes to work through financial oriented problems. The instructor also created lecture videos and information videos. We find evidence that video usage improves student performance. This finding is noteworthy since learning is the foremost goal of any instructional method. Students viewed the videos primarily for exam review. Students watched the videos and believed they were helpful and should be used in class. However, students do not necessarily want video classes to replace traditional classes. We make an important contribution by providing information about the usefulness of instructor generated videos to deliver course content.