cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.20278209.v1
title: Magnetic resonance imaging findings in patients with polymyalgia rheumatica

description: Abstract Objective: To describe the prevalence of magnetic resonance imaging (MRI) findings in patients with the clinical diagnosis of polymyalgia rheumatica (PMR). Materials and Methods: Sixteen consecutive patients with untreated PMR, meeting the American College of Rheumatology criteria, underwent MRI examinations of the shoulder(s), hip(s), or both, depending on clinical complaints. Six patients also underwent MRI of the spine. Results: We evaluated 24 shoulders, among which we identified subacromial-subdeltoid bursitis in 21 (87.5%), glenohumeral joint effusion in 17 (70.8%), and fluid distention of the long head of the biceps tendon sheath in 15 (62.5%). Peritendinitis and capsular edema were observed in 21 (87.5%) and 17 (70.8%) shoulders, respectively. We also evaluated 17 hips, identifying hip joint effusion in 12 (70.6%), trochanteric bursitis in 11 (64.7%), peritendinitis in 17 (100%), and capsular edema in 14 (82.4%). All six of the patients who underwent MRI of the spine were found to have interspinous bursitis. Conclusion: Subacromial-subdeltoid bursitis, glenohumeral joint effusion, and hip joint effusion are common findings in patients with PMR. In addition, such patients appear to be highly susceptible to peritendinitis and capsular edema. There is a need for case-control studies to validate our data and to determine the real impact that these findings have on the diagnosis of PMR by MRI.
DOI: 10.6084/m9.figshare.20278210
title: The use of Pilates for pain control in patients with fibromyalgia

description: Abstract Introduction: Although the Pilates method is commonly used to treat fibromyalgia (FM) in clinical practice, research is scarce, and little is known about its real effectiveness in pain management. Objective: Systematically review the literature to determine whether Pilates affects pain control in FM patients. Methods: The PubMed, Science Direct, PEDro and Cochrane databases were searched to identify randomized controlled trials that investigated the effects of Pilates in individuals diagnosed with FM. The descriptors used were: “pilates based exercise” OR “pilates training” OR “pilates exercise” OR “pilates” AND “fibromyalgia.” Independent reviewers performed abstract/full-text screening, data extraction, and methodological quality assessments using the PEDro scale. Results: The search identified 646 potential articles, four of which were used in the analysis. The Pilates method had positive effects on pain control, physical function, quality of life and biopsychosocial factors such as stress and depression in individuals with FM in four studies. However, improvement in these parameters did not differ between intervention groups in three studies. Additionally, the control group showed no significant improvement for the same parameters in one study. The PEDro scale scores of the studies ranged from 6 to 8 points. Conclusion: Evidence suggests that Pilates influences pain control in individuals with FM, and is more effective than no intervention or minimal intervention in the treatment of FM.
DOI: 10.6084/m9.figshare.20278210.v1
title: The use of Pilates for pain control in patients with fibromyalgia

description: Abstract Introduction: Although the Pilates method is commonly used to treat fibromyalgia (FM) in clinical practice, research is scarce, and little is known about its real effectiveness in pain management. Objective: Systematically review the literature to determine whether Pilates affects pain control in FM patients. Methods: The PubMed, Science Direct, PEDro and Cochrane databases were searched to identify randomized controlled trials that investigated the effects of Pilates in individuals diagnosed with FM. The descriptors used were: “pilates based exercise” OR “pilates training” OR “pilates exercise” OR “pilates” AND “fibromyalgia.” Independent reviewers performed abstract/full-text screening, data extraction, and methodological quality assessments using the PEDro scale. Results: The search identified 646 potential articles, four of which were used in the analysis. The Pilates method had positive effects on pain control, physical function, quality of life and biopsychosocial factors such as stress and depression in individuals with FM in four studies. However, improvement in these parameters did not differ between intervention groups in three studies. Additionally, the control group showed no significant improvement for the same parameters in one study. The PEDro scale scores of the studies ranged from 6 to 8 points. Conclusion: Evidence suggests that Pilates influences pain control in individuals with FM, and is more effective than no intervention or minimal intervention in the treatment of FM.
DOI: 10.6084/m9.figshare.20278212
title: Development and validation of analytical methods by HPLC for quality control of avermectins and milbemycins in bulk samples

description: Abstract This work aims to develop analytical methods using high-performance liquid chromatography with a diode array detector (HPLC-DAD) for analysis and quantification of avermectins (AVMs) and milbemycins (MBMs) in bulk samples. First, the methods were optimized and some parameters such as temperature, flow rate, injection volume and mobile phase with different proportions of solvents were evaluated. The best chromatographic conditions were obtained using the Phenomenex® C18 (150 × 4.60 mm, 5 μm) column at a temperature of 20 °C, flow rate of 1.2 mL min-1, injection volume of 20 μL, and detection at 250 nm. Acetonitrile: ultrapure water (87: 13, v/v) was used as mobile phase for moxidectin and eprinomectin, and acetonitrile: methanol: ultrapure water (53: 35: 12, v/v/v) for abamectin and ivermectin. Under these conditions satisfactory results were obtained, with appropriate limits of detection and quantification, acceptable linearity, precision, accuracy, and robustness. These methods satisfy the need for analytical methods for the multi-determination of MBMs and the B1a and B1b forms of AVMs by HPLC-DAD, which can be considered simple, effective, innovative and should aid in the development of the field.
DOI: 10.6084/m9.figshare.20278212.v1
title: Development and validation of analytical methods by HPLC for quality control of avermectins and milbemycins in bulk samples

description: Abstract This work aims to develop analytical methods using high-performance liquid chromatography with a diode array detector (HPLC-DAD) for analysis and quantification of avermectins (AVMs) and milbemycins (MBMs) in bulk samples. First, the methods were optimized and some parameters such as temperature, flow rate, injection volume and mobile phase with different proportions of solvents were evaluated. The best chromatographic conditions were obtained using the Phenomenex® C18 (150 × 4.60 mm, 5 μm) column at a temperature of 20 °C, flow rate of 1.2 mL min-1, injection volume of 20 μL, and detection at 250 nm. Acetonitrile: ultrapure water (87: 13, v/v) was used as mobile phase for moxidectin and eprinomectin, and acetonitrile: methanol: ultrapure water (53: 35: 12, v/v/v) for abamectin and ivermectin. Under these conditions satisfactory results were obtained, with appropriate limits of detection and quantification, acceptable linearity, precision, accuracy, and robustness. These methods satisfy the need for analytical methods for the multi-determination of MBMs and the B1a and B1b forms of AVMs by HPLC-DAD, which can be considered simple, effective, innovative and should aid in the development of the field.
DOI: 10.6084/m9.figshare.20278213
title: Interictal and postictal 18F-FDG PET/CT in epileptogenic zone localization

description: Abstract Objective: To evaluate the performance of 18F-fluorodeoxyglucose positron-emission tomography/computed tomography ( 18F-FDG PET/CT) in localizing epileptogenic zones, comparing 18F-FDG injection performed in the traditional interictal period with that performed near the time of a seizure. Materials and Methods: We evaluated patients with refractory epilepsy who underwent 18F-FDG PET/CT. The reference standards for localization of the epileptogenic zone were histopathology and follow-up examinations (in patients who underwent surgery) or serial electroencephalography (EEG) recordings, long-term video EEG, and magnetic resonance imaging (in patients who did not). The 18F-FDG injection was performed whether the patient had an epileptic seizure during the EEG monitoring period or not. The 18F-FDG PET/CT results were categorized as concordant or discordant with the reference standards. Results: Of the 110 patients evaluated, 10 were in a postictal group (FDG injection after a seizure) and 100 were in the interictal group. The 18F-FDG PET/CT was concordant with the reference standards in nine (90%) of the postictal group patients and in 60 (60%) of the interictal group patients. Among the nine postictal group patients in whom the results were concordant, the 18F-FDG PET/CT showed hypermetabolism and hypometabolism in the epileptogenic zone in four (44.4%) and five (55.6%), respectively. Conclusion: Our data indicate that 18F-FDG PET/CT is a helpful tool for localization of the epileptogenic zone and that EEG monitoring is an important means of correlating the findings. In addition, postictal 18F-FDG PET/CT is able to identify the epileptogenic zone by showing either hypometabolism or hypermetabolism.
DOI: 10.6084/m9.figshare.20278213.v1
title: Interictal and postictal 18F-FDG PET/CT in epileptogenic zone localization

description: Abstract Objective: To evaluate the performance of 18F-fluorodeoxyglucose positron-emission tomography/computed tomography ( 18F-FDG PET/CT) in localizing epileptogenic zones, comparing 18F-FDG injection performed in the traditional interictal period with that performed near the time of a seizure. Materials and Methods: We evaluated patients with refractory epilepsy who underwent 18F-FDG PET/CT. The reference standards for localization of the epileptogenic zone were histopathology and follow-up examinations (in patients who underwent surgery) or serial electroencephalography (EEG) recordings, long-term video EEG, and magnetic resonance imaging (in patients who did not). The 18F-FDG injection was performed whether the patient had an epileptic seizure during the EEG monitoring period or not. The 18F-FDG PET/CT results were categorized as concordant or discordant with the reference standards. Results: Of the 110 patients evaluated, 10 were in a postictal group (FDG injection after a seizure) and 100 were in the interictal group. The 18F-FDG PET/CT was concordant with the reference standards in nine (90%) of the postictal group patients and in 60 (60%) of the interictal group patients. Among the nine postictal group patients in whom the results were concordant, the 18F-FDG PET/CT showed hypermetabolism and hypometabolism in the epileptogenic zone in four (44.4%) and five (55.6%), respectively. Conclusion: Our data indicate that 18F-FDG PET/CT is a helpful tool for localization of the epileptogenic zone and that EEG monitoring is an important means of correlating the findings. In addition, postictal 18F-FDG PET/CT is able to identify the epileptogenic zone by showing either hypometabolism or hypermetabolism.
DOI: 10.6084/m9.figshare.20278215.v1
title: Maturation and germination of Trichosanthes cucumerina L. seeds

description: Abstract: Trichosanthes cucumerina L. (Cucurbitaceae) is a traditional fruit vegetable grown by family farmers in the Amazon. This study aimed to evaluate seed maturation as a function of age and fruit morphological characteristics, and the effect of different temperatures on seed germination of accessions of the species. A completely randomized design was adopted in the maturation study, with five treatments (fruit age: 20, 30, 40, 50, and 60 days after anthesis - DAA) and four replications. Seed quality was evaluated through dry mass, water content, germination, and vigor variables, while the fruits were evaluated for physical characteristics and the number of seeds. A completely randomized design in a 3 (temperatures: 20, 25, and 30 °C) x 7 (accessions: PIN I, PIN II, TSA, MAO, UTB, ITA, and IMI) factorial scheme, with four replications was adopted in the study of germination temperatures. Seed quality was evaluated using germination and vigor tests. Seeds reach physiological maturity around 50 DAA. The fruits are partially or completely orange or reddish-orange in color at that time. The temperature of 30 °C favored the seed germination process, resulting in a higher percentage and germination rate.
DOI: 10.6084/m9.figshare.20278215
title: Maturation and germination of Trichosanthes cucumerina L. seeds

description: Abstract: Trichosanthes cucumerina L. (Cucurbitaceae) is a traditional fruit vegetable grown by family farmers in the Amazon. This study aimed to evaluate seed maturation as a function of age and fruit morphological characteristics, and the effect of different temperatures on seed germination of accessions of the species. A completely randomized design was adopted in the maturation study, with five treatments (fruit age: 20, 30, 40, 50, and 60 days after anthesis - DAA) and four replications. Seed quality was evaluated through dry mass, water content, germination, and vigor variables, while the fruits were evaluated for physical characteristics and the number of seeds. A completely randomized design in a 3 (temperatures: 20, 25, and 30 °C) x 7 (accessions: PIN I, PIN II, TSA, MAO, UTB, ITA, and IMI) factorial scheme, with four replications was adopted in the study of germination temperatures. Seed quality was evaluated using germination and vigor tests. Seeds reach physiological maturity around 50 DAA. The fruits are partially or completely orange or reddish-orange in color at that time. The temperature of 30 °C favored the seed germination process, resulting in a higher percentage and germination rate.
DOI: 10.6084/m9.figshare.20278221
title: Levels of impulsivity in individuals with cannabis use disorder

description: Abstract Introduction Substance use disorder consists of the presence of cognitive, behavioral, and physiological symptoms, indicating continuous use of one or more substances by the individual. The literature points to the existence of a relationship between impulsive behavior, in which individuals tend to act thoughtlessly and with a lower level of planning, and consumption of substances including cannabis. Objectives To examine the presence and severity of impulsivity in individuals with cannabis use disorder and investigate associations between sociodemographic and clinical characteristics and impulsivity. Method Participants completed a sociodemographic data sheet and the Barratt Impulsiveness Scale (BIS-11). A total of 122 subjects with a diagnosis of cannabis use disorder participated, with a mean age of 34.46 years (standard deviation = 9.62). Results The prevalence of high levels of impulsivity in the sample ranged from 30 to 33%; the BIS-11 total score was significantly associated with cohabitation and alcohol use. The BIS-11 scores for motor impulsivity and attentional impulsivity were also associated with consumption of alcohol. No associations were found between impulsivity and the variables age, education, use of tobacco, or use of cocaine/crack. Conclusion This study contributes to understanding of substance dependence, especially cannabis. It found presence of impulsive behavior among individuals with cannabis use disorder, which is corroborated by reports in the literature.
DOI: 10.6084/m9.figshare.20278221.v1
title: Levels of impulsivity in individuals with cannabis use disorder

description: Abstract Introduction Substance use disorder consists of the presence of cognitive, behavioral, and physiological symptoms, indicating continuous use of one or more substances by the individual. The literature points to the existence of a relationship between impulsive behavior, in which individuals tend to act thoughtlessly and with a lower level of planning, and consumption of substances including cannabis. Objectives To examine the presence and severity of impulsivity in individuals with cannabis use disorder and investigate associations between sociodemographic and clinical characteristics and impulsivity. Method Participants completed a sociodemographic data sheet and the Barratt Impulsiveness Scale (BIS-11). A total of 122 subjects with a diagnosis of cannabis use disorder participated, with a mean age of 34.46 years (standard deviation = 9.62). Results The prevalence of high levels of impulsivity in the sample ranged from 30 to 33%; the BIS-11 total score was significantly associated with cohabitation and alcohol use. The BIS-11 scores for motor impulsivity and attentional impulsivity were also associated with consumption of alcohol. No associations were found between impulsivity and the variables age, education, use of tobacco, or use of cocaine/crack. Conclusion This study contributes to understanding of substance dependence, especially cannabis. It found presence of impulsive behavior among individuals with cannabis use disorder, which is corroborated by reports in the literature.
DOI: 10.6084/m9.figshare.20278219.v1
title: Common and uncommon neuroimaging manifestations of ataxia: an illustrated guide for the trainee radiologist. Part 2 - neoplastic, congenital, degenerative, and hereditary diseases

description: Abstract Ataxia is defined as a lack of coordination of voluntary movement, caused by a variety of factors. Ataxia can be classified by the age at onset and type (chronic or acute). The causative lesions involve the cerebellum and cerebellar connections. The correct, appropriate use of neuroimaging, particularly magnetic resonance imaging, can make the diagnosis relatively straightforward and facilitate implementation of the appropriate clinical management. The purpose of this pictorial essay is to describe the imaging findings of ataxia, based on cases obtained from the archives of a tertiary care hospital, with a review of the most important findings. We also discuss and review the imaging aspects of neoplastic diseases, malformations, degenerative diseases, and hereditary diseases related to ataxia.
DOI: 10.6084/m9.figshare.20278219
title: Common and uncommon neuroimaging manifestations of ataxia: an illustrated guide for the trainee radiologist. Part 2 - neoplastic, congenital, degenerative, and hereditary diseases

description: Abstract Ataxia is defined as a lack of coordination of voluntary movement, caused by a variety of factors. Ataxia can be classified by the age at onset and type (chronic or acute). The causative lesions involve the cerebellum and cerebellar connections. The correct, appropriate use of neuroimaging, particularly magnetic resonance imaging, can make the diagnosis relatively straightforward and facilitate implementation of the appropriate clinical management. The purpose of this pictorial essay is to describe the imaging findings of ataxia, based on cases obtained from the archives of a tertiary care hospital, with a review of the most important findings. We also discuss and review the imaging aspects of neoplastic diseases, malformations, degenerative diseases, and hereditary diseases related to ataxia.
DOI: 10.6084/m9.figshare.20278225
title: The BigFLUX Magnetic Matrix Technology

description: Abstract The Magnetic separation of ultra-fine ore particles has always posed a challenge to the JONES/WHIMS process. Despite many advances in this technology, no effective improvement has been made to its core component: The Magnetic Matrix. The current approach to separate ultra-fine particles teaches that the gap of the matrix and its teeth size must be smaller than usual in order to accommodate the small size of the particles. However, practice proved this approach to be far from ideal. The closing of the gap between grooved plates, whose teeth are smaller, drastically reduces the flow area, reduces the feed capacity, and makes the matrices prone to clogging. In addition, smaller teeth reduce the magnetic field and its gradient, leading to poor results with ultra-fine ore particles. This research proves that bigger teeth are better suited for high intensity magnetic separation of ultra-fines because they avoid matrix clogging thanks to the larger slurry flow area. Additionally, bigger teeth amplify the magnetic field “Bmax” and increases the magnetic gradient “Grad (∆B /∆X)”. The positive results of this new “BigFLUX Matrix” technology, are being displayed in several mining operations worldwide, increasing metallurgical recovery and producing high quality concentrates and low iron content sand from iron ore tailings.
DOI: 10.6084/m9.figshare.20278225.v1
title: The BigFLUX Magnetic Matrix Technology

description: Abstract The Magnetic separation of ultra-fine ore particles has always posed a challenge to the JONES/WHIMS process. Despite many advances in this technology, no effective improvement has been made to its core component: The Magnetic Matrix. The current approach to separate ultra-fine particles teaches that the gap of the matrix and its teeth size must be smaller than usual in order to accommodate the small size of the particles. However, practice proved this approach to be far from ideal. The closing of the gap between grooved plates, whose teeth are smaller, drastically reduces the flow area, reduces the feed capacity, and makes the matrices prone to clogging. In addition, smaller teeth reduce the magnetic field and its gradient, leading to poor results with ultra-fine ore particles. This research proves that bigger teeth are better suited for high intensity magnetic separation of ultra-fines because they avoid matrix clogging thanks to the larger slurry flow area. Additionally, bigger teeth amplify the magnetic field “Bmax” and increases the magnetic gradient “Grad (∆B /∆X)”. The positive results of this new “BigFLUX Matrix” technology, are being displayed in several mining operations worldwide, increasing metallurgical recovery and producing high quality concentrates and low iron content sand from iron ore tailings.
DOI: 10.6084/m9.figshare.20278227
title: Effects of glucocorticoids on interstitial glucose concentrations in individuals with hematologic cancer and without known diagnosis of diabetes: a pilot study

description: ABSTRACT Objective To analyze interstitial glucose behavior during glucocorticoid use in non-diabetic patients receiving chemotherapy for hematologic malignancies. Methods Prospective pilot study carried out to assess interstitial glucose levels in 15 non-diabetic individuals with hematologic malignancies who received glucocorticoids in combination with chemotherapy. The FreeStyle Libre flash monitoring system (Abbott Diabetes Care) was used for up to 14 days to measure interstitial glucose. Results Median age and body mass index were 53 (42-61) years and 25 (23-28) kg/m2 respectively. Interstitial glucose levels &gt;180mg/dL lasting at least one hour were detected in 60% of participants. Interstitial glucose profile parameters (median and peak interstitial glucose levels and percentage of time during which interstitial glucose levels were &gt;180mg/dL) were significantly (p&lt;0.01) higher during glucocorticoid use (115mg/dL, 218mg/dL and 10% respectively) than after glucocorticoid discontinuation (97mg/dL, 137mg/dL and 0% respectively). Mean interstitial glucose levels increased in the afternoon and at night during glucocorticoid use. Conclusion This pilot study was the first to evaluate interstitial glucose levels in non-diabetic individuals using glucocorticoids in treatment of hematologic cancer. Glucocorticoid use during chemotherapy significantly increases interstitial glucose levels in these patients.