cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.8117852
title: Transgenerational sperm DNA methylation epimutation developmental origins following ancestral vinclozolin exposure

description: A number of environmental factors from nutrition to toxicants have been shown to promote the epigenetic transgenerational inheritance of disease and phenotypic variation. This requires alterations in the germline (sperm or egg) epigenome. Previously, the agricultural fungicide vinclozolin was found to promote the transgenerational inheritance of sperm differential DNA methylation regions (DMRs) termed epimutations that help mediate this epigenetic inheritance. The current study was designed to investigate the developmental origins of the transgenerational DMRs during gametogenesis. Male control and vinclozolin lineage F3 generation rats were used as a source of embryonic day 13 (E13) primordial germ cells, embryonic day 16 (E16) prospermatogonia, postnatal day 10 (P10) spermatogonia, adult pachytene spermatocytes, round spermatids, caput epididymal spermatozoa, and caudal sperm. The DMRs between the control versus vinclozolin lineage samples were determined for each developmental stage. The top 100 statistically significant DMRs for each stage were compared. The developmental origins of the caudal epididymal sperm DMRs were assessed. The chromosomal locations and genomic features of the different stage DMRs were investigated. In addition, the DMR associated genes were identified. Previous studies have demonstrated alterations in the DMRs of primordial germ cells (PGCs). Interestingly, the majority of the DMRs identified in the current study for the caudal sperm originated during the spermatogenic process in the testis. A cascade of epigenetic alterations initiated in the PGCs appears to be required to alter the epigenetic programming during spermatogenesis to modify the sperm epigenome involved in the transgenerational epigenetic inheritance phenomenon.
DOI: 10.6084/m9.figshare.8117852.v2
title: Transgenerational sperm DNA methylation epimutation developmental origins following ancestral vinclozolin exposure

description: A number of environmental factors from nutrition to toxicants have been shown to promote the epigenetic transgenerational inheritance of disease and phenotypic variation. This requires alterations in the germline (sperm or egg) epigenome. Previously, the agricultural fungicide vinclozolin was found to promote the transgenerational inheritance of sperm differential DNA methylation regions (DMRs) termed epimutations that help mediate this epigenetic inheritance. The current study was designed to investigate the developmental origins of the transgenerational DMRs during gametogenesis. Male control and vinclozolin lineage F3 generation rats were used as a source of embryonic day 13 (E13) primordial germ cells, embryonic day 16 (E16) prospermatogonia, postnatal day 10 (P10) spermatogonia, adult pachytene spermatocytes, round spermatids, caput epididymal spermatozoa, and caudal sperm. The DMRs between the control versus vinclozolin lineage samples were determined for each developmental stage. The top 100 statistically significant DMRs for each stage were compared. The developmental origins of the caudal epididymal sperm DMRs were assessed. The chromosomal locations and genomic features of the different stage DMRs were investigated. In addition, the DMR associated genes were identified. Previous studies have demonstrated alterations in the DMRs of primordial germ cells (PGCs). Interestingly, the majority of the DMRs identified in the current study for the caudal sperm originated during the spermatogenic process in the testis. A cascade of epigenetic alterations initiated in the PGCs appears to be required to alter the epigenetic programming during spermatogenesis to modify the sperm epigenome involved in the transgenerational epigenetic inheritance phenomenon.
DOI: 10.6084/m9.figshare.8117852.v1
title: Transgenerational sperm DNA methylation epimutation developmental origins following ancestral vinclozolin exposure

description: A number of environmental factors from nutrition to toxicants have been shown to promote the epigenetic transgenerational inheritance of disease and phenotypic variation. This requires alterations in the germline (sperm or egg) epigenome. Previously, the agricultural fungicide vinclozolin was found to promote the transgenerational inheritance of sperm differential DNA methylation regions (DMRs) termed epimutations that help mediate this epigenetic inheritance. The current study was designed to investigate the developmental origins of the transgenerational DMRs during gametogenesis. Male control and vinclozolin lineage F3 generation rats were used as a source of embryonic day 13 (E13) primordial germ cells, embryonic day 16 (E16) prospermatogonia, postnatal day 10 (P10) spermatogonia, adult pachytene spermatocytes, round spermatids, caput epididymal spermatozoa, and caudal sperm. The DMRs between the control versus vinclozolin lineage samples were determined for each developmental stage. The top 100 statistically significant DMRs for each stage were compared. The developmental origins of the caudal epididymal sperm DMRs were assessed. The chromosomal locations and genomic features of the different stage DMRs were investigated. In addition, the DMR associated genes were identified. Previous studies have demonstrated alterations in the DMRs of primordial germ cells (PGCs). Interestingly, the majority of the DMRs identified in the current study for the caudal sperm originated during the spermatogenic process in the testis. A cascade of epigenetic alterations initiated in the PGCs appears to be required to alter the epigenetic programming during spermatogenesis to modify the sperm epigenome involved in the transgenerational epigenetic inheritance phenomenon.
DOI: 10.6084/m9.figshare.8117843
title: hawkes_et_al_data from Sexual selection drives the evolution of male wing interference patterns

description: This is all the raw data
DOI: 10.6084/m9.figshare.8117840
title: New supplemtary tables from Sexual selection drives the evolution of male wing interference patterns

description: A list of full statistical models for wing data
DOI: 10.6084/m9.figshare.8117843.v1
title: hawkes_et_al_data from Sexual selection drives the evolution of male wing interference patterns

description: This is all the raw data
DOI: 10.6084/m9.figshare.8117837
title: Experimental Data from A mathematical model for a biphasic dna amplification reaction

description: This file contains the raw data shown in Figure 1 and Figures 4-7
DOI: 10.6084/m9.figshare.8117837.v1
title: Experimental Data from A mathematical model for a biphasic dna amplification reaction

description: This file contains the raw data shown in Figure 1 and Figures 4-7
DOI: 10.6084/m9.figshare.8117831
title: Matlab code from A mathematical model for a biphasic dna amplification reaction

description: This is the matlab file (.m) that was used to solve the system of ODEs described in the manuscript.
DOI: 10.6084/m9.figshare.8117774.v1
title: Patient and caregiver experiences on care transitions for adults with a hip fracture: a scoping review

description: <b>Purpose:</b> The purpose of this scoping review was to explore the literature on experiences and perspectives of patients with hip fractures and their caregivers during transitions in care. <b>Methods:</b> Seven databases were searched for studies published between 1 January 2000 and 3 July 2018. Grey literature was also searched. <b>Results:</b> Eleven articles met the inclusion criteria. The scoping review found that patients and caregivers encounter several challenges during care transitions including the following: lack of information sharing, role confusion and disorganized discharge planning. Common suggestions reported in the literature for improving care transitions were: increasing written communication, offering a patient representative role, using technology for knowledge dissemination and increasing geriatrician involvement. <b>Conclusions:</b> The results of this scoping review provide a useful foundation from which to build strategies to address challenges such as lack of information sharing, role confusion and disorganized discharge planning experienced by patients and caregivers during care transitions. Further research needs to explore the development of strategies to promote patient-centered care especially during discharge from an acute care facility.Implications for rehabilitationEncourage health care providers to collaborate with patients with hip fracture and caregivers on decision-making about rehabilitation and recovery goals, discharge planning and safe patient transfer.Assess the needs of patients with hip fracture and caregivers before, during and after a care transition to deliver patient and family-centered care across multiple care settings.Provide patients with hip fracture and caregivers standardized information-exchange tools to increase timely, accurate exchange of information during care transitions.Encourage formal discussions about roles and responsibilities in the transitions in care process among patients with hip fracture, caregivers and health care providers. Encourage health care providers to collaborate with patients with hip fracture and caregivers on decision-making about rehabilitation and recovery goals, discharge planning and safe patient transfer. Assess the needs of patients with hip fracture and caregivers before, during and after a care transition to deliver patient and family-centered care across multiple care settings. Provide patients with hip fracture and caregivers standardized information-exchange tools to increase timely, accurate exchange of information during care transitions. Encourage formal discussions about roles and responsibilities in the transitions in care process among patients with hip fracture, caregivers and health care providers.
DOI: 10.6084/m9.figshare.12871547.v1
title: SuppTab1.docx

description: Top loadings for PC1, PC2 and PC3 from the PCA analysis of the 1506 protein abundances of 96 stickleback from four populations inhabiting different environements.
DOI: 10.6084/m9.figshare.8117711
title: manuscript.doc

description: manuscript
DOI: 10.6084/m9.figshare.8117711.v1
title: manuscript.doc

description: manuscript
DOI: 10.6084/m9.figshare.8116169
title: UG.33Grapes.Total.SNP.final.miss90.maf10.SIFT.vcf.gz

description: Prediction of functional effects of candidate SNP variants detected by analysis of genome resequencing data from 33 grape accessions using SIFT
DOI: 10.6084/m9.figshare.8116169.v1
title: UG.33Grapes.Total.SNP.final.miss90.maf10.SIFT.vcf.gz

description: Prediction of functional effects of candidate SNP variants detected by analysis of genome resequencing data from 33 grape accessions using SIFT
DOI: 10.6084/m9.figshare.8116166
title: 33Grapes.Total.SNP.final.Pltd.vcf.gz

description: Candidate SNP variants detected by analysis of genome resequencing data from 33 grape accessions
DOI: 10.6084/m9.figshare.8116166.v2
title: 33Grapes.Total.SNP.final.Pltd.vcf.gz

description: Candidate SNP variants detected by analysis of genome resequencing data from 33 grape accessions
DOI: 10.6084/m9.figshare.8116166.v1
title: 33Grapes.Total.SNP.final.Pltd.vcf.gz

description: Candidate SNP variants detected by analysis of genome resequencing data from 33 grape accessions
DOI: 10.6084/m9.figshare.8116163
title: 33Grapes.Total.SNP.final.MT.vcf.gz

description: Candidate SNP variants detected by analysis of genome resequencing data from 33 grape accessions
DOI: 10.6084/m9.figshare.8116163.v1
title: 33Grapes.Total.SNP.final.MT.vcf.gz

description: Candidate SNP variants detected by analysis of genome resequencing data from 33 grape accessions
DOI: 10.6084/m9.figshare.8116160
title: 33Grapes.Total.SNP.final.chr19.vcf.gz

description: Candidate SNP variants detected by analysis of genome resequencing data from 33 grape accessions
DOI: 10.6084/m9.figshare.8116160.v1
title: 33Grapes.Total.SNP.final.chr19.vcf.gz

description: Candidate SNP variants detected by analysis of genome resequencing data from 33 grape accessions
DOI: 10.6084/m9.figshare.8116157
title: 33Grapes.Total.SNP.final.chr18.vcf.gz

description: Candidate SNP variants detected by analysis of genome resequencing data from 33 grape accessions
DOI: 10.6084/m9.figshare.8116157.v1
title: 33Grapes.Total.SNP.final.chr18.vcf.gz

description: Candidate SNP variants detected by analysis of genome resequencing data from 33 grape accessions
DOI: 10.6084/m9.figshare.8116142
title: 33Grapes.Total.SNP.final.chr17.vcf.gz

description: Candidate SNP variants detected by analysis of genome resequencing data from 33 grape accessions
DOI: 10.6084/m9.figshare.8116142.v1
title: 33Grapes.Total.SNP.final.chr17.vcf.gz

description: Candidate SNP variants detected by analysis of genome resequencing data from 33 grape accessions
DOI: 10.6084/m9.figshare.8116139
title: 33Grapes.Total.SNP.final.chr16.vcf.gz

description: Candidate SNP variants detected by analysis of genome resequencing data from 33 grape accessions
DOI: 10.6084/m9.figshare.8116139.v1
title: 33Grapes.Total.SNP.final.chr16.vcf.gz

description: Candidate SNP variants detected by analysis of genome resequencing data from 33 grape accessions
DOI: 10.6084/m9.figshare.8116136
title: 33Grapes.Total.SNP.final.chr15.vcf.gz

description: Candidate SNP variants detected by analysis of genome resequencing data from 33 grape accessions
DOI: 10.6084/m9.figshare.8116136.v1
title: 33Grapes.Total.SNP.final.chr15.vcf.gz

description: Candidate SNP variants detected by analysis of genome resequencing data from 33 grape accessions
DOI: 10.6084/m9.figshare.8116133
title: 33Grapes.Total.SNP.final.chr14.vcf.gz

description: Candidate SNP variants detected by analysis of genome resequencing data from 33 grape accessions
DOI: 10.6084/m9.figshare.8116133.v1
title: 33Grapes.Total.SNP.final.chr14.vcf.gz

description: Candidate SNP variants detected by analysis of genome resequencing data from 33 grape accessions
DOI: 10.6084/m9.figshare.8116130
title: 33Grapes.Total.SNP.final.chr13.vcf.gz

description: Candidate SNP variants detected by analysis of genome resequencing data from 33 grape accessions
DOI: 10.6084/m9.figshare.8116130.v1
title: 33Grapes.Total.SNP.final.chr13.vcf.gz

description: Candidate SNP variants detected by analysis of genome resequencing data from 33 grape accessions
DOI: 10.6084/m9.figshare.8116127
title: 33Grapes.Total.SNP.final.chr12.vcf.gz

description: Candidate SNP variants detected by analysis of genome resequencing data from 33 grape accessions
DOI: 10.6084/m9.figshare.8116127.v1
title: 33Grapes.Total.SNP.final.chr12.vcf.gz

description: Candidate SNP variants detected by analysis of genome resequencing data from 33 grape accessions
DOI: 10.6084/m9.figshare.8116121
title: 33Grapes.Total.SNP.final.chr11.vcf.gz

description: Candidate SNP variants detected by analysis of genome resequencing data from 33 grape accessions
DOI: 10.6084/m9.figshare.8116121.v1
title: 33Grapes.Total.SNP.final.chr11.vcf.gz

description: Candidate SNP variants detected by analysis of genome resequencing data from 33 grape accessions
DOI: 10.6084/m9.figshare.8116118
title: 33Grapes.Total.SNP.final.chr10.vcf.gz

description: Candidate SNP variants detected by analysis of genome resequencing data from 33 grape accessions
DOI: 10.6084/m9.figshare.8116118.v1
title: 33Grapes.Total.SNP.final.chr10.vcf.gz

description: Candidate SNP variants detected by analysis of genome resequencing data from 33 grape accessions
DOI: 10.6084/m9.figshare.8116115
title: 33Grapes.Total.SNP.final.chr09.vcf.gz

description: Candidate SNP variants detected by analysis of genome resequencing data from 33 grape accessions
DOI: 10.6084/m9.figshare.8116115.v1
title: 33Grapes.Total.SNP.final.chr09.vcf.gz

description: Candidate SNP variants detected by analysis of genome resequencing data from 33 grape accessions
DOI: 10.6084/m9.figshare.8116112
title: 33Grapes.Total.SNP.final.chr08.vcf.gz

description: Candidate SNP variants detected by analysis of genome resequencing data from 33 grape accessions
DOI: 10.6084/m9.figshare.8116112.v1
title: 33Grapes.Total.SNP.final.chr08.vcf.gz

description: Candidate SNP variants detected by analysis of genome resequencing data from 33 grape accessions
DOI: 10.6084/m9.figshare.8116109
title: 33Grapes.Total.SNP.final.chr07.vcf.gz

description: Candidate SNP variants detected by analysis of genome resequencing data from 33 grape accessions
DOI: 10.6084/m9.figshare.8116109.v1
title: 33Grapes.Total.SNP.final.chr07.vcf.gz

description: Candidate SNP variants detected by analysis of genome resequencing data from 33 grape accessions
DOI: 10.6084/m9.figshare.8116106
title: 33Grapes.Total.SNP.final.chr06.vcf.gz

description: Candidate SNP variants detected by analysis of genome resequencing data from 33 grape accessions
DOI: 10.6084/m9.figshare.8116106.v1
title: 33Grapes.Total.SNP.final.chr06.vcf.gz

description: Candidate SNP variants detected by analysis of genome resequencing data from 33 grape accessions
DOI: 10.6084/m9.figshare.8116103
title: 33Grapes.Total.SNP.final.chr05.vcf.gz

description: Candidate SNP variants detected by analysis of genome resequencing data from 33 grape accessions
DOI: 10.6084/m9.figshare.8116103.v1
title: 33Grapes.Total.SNP.final.chr05.vcf.gz

description: Candidate SNP variants detected by analysis of genome resequencing data from 33 grape accessions
DOI: 10.17608/k6.auckland.8116097
title: Supplementary_tables_metabolites.xlsx

description: We identified proximal and distal target genes for 145 genome-wide significant metabolite-associated SNPs by the systematic integration of chromatin interaction (Hi-C), expression quantitative trait loci (eQTL), gene ontology (KEGG), protein classification (The Human Protein Atlas), drug-gene interaction (DGIdb), and literature text mining (PubMed) data. Our approach revealed that ~90% of the metabolite-associated SNPs are eQTLs. These SNPs form 612 distinct eSNP-eGene interactions via chromatin looping across 48 human tissues.
DOI: 10.7925/drs1.duchas_4453790
title: Games

description: Story collected by Michael J. Hanley, a student at Cill Moibhí (B) school (Kilmovee, Co. Mayo) (no informant identified).
description: Collected as part of the Schools' Folklore scheme, 1937-1938, under the supervision of teacher Mícheál Ó Labhartaigh.
description: Supported by funding from the Department of Arts, Heritage and the Gaeltacht (Ireland), University College Dublin, and the National Folklore Foundation (Fondúireacht Bhéaloideas Éireann), 2014-2016.
DOI: 10.7925/drs1.duchas_4453791
title: Scoileanna Cois Claí

description: Story collected by a student at Caurane (C.) school (Caurans Lower, Co. Mayo) from informant Páraic de Róiste.
description: Collected as part of the Schools' Folklore scheme, 1937-1938, under the supervision of teacher Bean Uí Fhaoláin.
description: Supported by funding from the Department of Arts, Heritage and the Gaeltacht (Ireland), University College Dublin, and the National Folklore Foundation (Fondúireacht Bhéaloideas Éireann), 2014-2016.
DOI: 10.7925/drs1.duchas_4453792
title: Games

description: Story collected by John Duffy, a student at Cill Moibhí (B) school (Kilmovee, Co. Mayo) (no informant identified).
description: Collected as part of the Schools' Folklore scheme, 1937-1938, under the supervision of teacher Mícheál Ó Labhartaigh.
description: Supported by funding from the Department of Arts, Heritage and the Gaeltacht (Ireland), University College Dublin, and the National Folklore Foundation (Fondúireacht Bhéaloideas Éireann), 2014-2016.
DOI: 10.7925/drs1.duchas_4453793
title: Riddles

description: Story collected by a student at Tón Ruadh school (Tonroe, Co. Mayo) (no informant identified).
description: Collected as part of the Schools' Folklore scheme, 1937-1938, under the supervision of teacher Máirtín Ó Giobaláin.
description: Supported by funding from the Department of Arts, Heritage and the Gaeltacht (Ireland), University College Dublin, and the National Folklore Foundation (Fondúireacht Bhéaloideas Éireann), 2014-2016.
DOI: 10.7925/drs1.duchas_4453794
title: Seanscéal Eile

description: Story collected by Brighid Ní Mhóráin, a student at Caurane (C.) school (Caurans Lower, Co. Mayo) from informant Mártan Ó Móráin.
description: Collected as part of the Schools' Folklore scheme, 1937-1938, under the supervision of teacher Bean Uí Fhaoláin.
description: Supported by funding from the Department of Arts, Heritage and the Gaeltacht (Ireland), University College Dublin, and the National Folklore Foundation (Fondúireacht Bhéaloideas Éireann), 2014-2016.
DOI: 10.7925/drs1.duchas_4453795
title: Townlands

description: Story collected by a student at Maolach Mór school (Meelick More, Co. Mayo) (no informant identified).
description: Collected as part of the Schools' Folklore scheme, 1937-1938, under the supervision of teacher Seán Mac Coisdealbha.
description: Supported by funding from the Department of Arts, Heritage and the Gaeltacht (Ireland), University College Dublin, and the National Folklore Foundation (Fondúireacht Bhéaloideas Éireann), 2014-2016.
DOI: 10.7925/drs1.duchas_4453796
title: Funny Stories

description: Story collected by Eibhlín Ní Gabhláin, a student at Tón Ruadh school (Tonroe, Co. Mayo) (no informant identified).
description: Collected as part of the Schools' Folklore scheme, 1937-1938, under the supervision of teacher Máirtín Ó Giobaláin.
description: Supported by funding from the Department of Arts, Heritage and the Gaeltacht (Ireland), University College Dublin, and the National Folklore Foundation (Fondúireacht Bhéaloideas Éireann), 2014-2016.
DOI: 10.7925/drs1.duchas_4453797
title: Landlords

description: Story collected by a student at Maolach Mór school (Meelick More, Co. Mayo) (no informant identified).
description: Collected as part of the Schools' Folklore scheme, 1937-1938, under the supervision of teacher Seán Mac Coisdealbha.
description: Supported by funding from the Department of Arts, Heritage and the Gaeltacht (Ireland), University College Dublin, and the National Folklore Foundation (Fondúireacht Bhéaloideas Éireann), 2014-2016.
DOI: 10.7925/drs1.duchas_4453798
title: Áiteacha Cáiliúla sa gCeantar

description: Story collected by Peggi Ní Congaile, a student at Caurane (C.) school (Caurans Lower, Co. Mayo) from informant Páraic Mac Congaile.
description: Collected as part of the Schools' Folklore scheme, 1937-1938, under the supervision of teacher Bean Uí Fhaoláin.
description: Supported by funding from the Department of Arts, Heritage and the Gaeltacht (Ireland), University College Dublin, and the National Folklore Foundation (Fondúireacht Bhéaloideas Éireann), 2014-2016.
DOI: 10.7925/drs1.duchas_4453799
title: Cures

description: Story collected by a student at Maolach Mór school (Meelick More, Co. Mayo) (no informant identified).
description: Collected as part of the Schools' Folklore scheme, 1937-1938, under the supervision of teacher Seán Mac Coisdealbha.
description: Supported by funding from the Department of Arts, Heritage and the Gaeltacht (Ireland), University College Dublin, and the National Folklore Foundation (Fondúireacht Bhéaloideas Éireann), 2014-2016.
DOI: 10.7925/drs1.duchas_4453800
title: Cloonmore House and Its Estate

description: Story collected by Eibhlín Ní Gabhláin, a student at Tón Ruadh school (Tonroe, Co. Mayo) from 2 informants.
description: Collected as part of the Schools' Folklore scheme, 1937-1938, under the supervision of teacher Máirtín Ó Giobaláin.
description: Supported by funding from the Department of Arts, Heritage and the Gaeltacht (Ireland), University College Dublin, and the National Folklore Foundation (Fondúireacht Bhéaloideas Éireann), 2014-2016.