cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.18712/nsd-nsd2811-v1
title: Database on the hospital administrative apparatus, health institutions, 1989

description: The data collection "Database on the hospital administrative apparatus" was part of the "Program for healthcare research", initiated and financed by the Research Council of Norway and the Norwegian Council for Applied Social Research (NORAS). Norwegian Centre for Research Data (now Sikt - Norwegian Agency for Shared Services in Education and Research) was responsible for the data collection. The database formed a general starting point that gave an almost total overview of all health (related) institutions in Norway in 1988. From this total overview, 130 central institutions, somatic and psychiatric hospitals (and departments) were singled out as units in further data collection. This was supplemented with information on how the hospital's administrative apparatus is structured, its job structure and the staff's competence profile. As a measure of competence, information was collected on highest education, further education and seniority.
DOI: 10.25502/ykeg-ry71/d
title: Données des producteurs atteints dans la composante chaine de valeur manioc au Tanganyika

description: PICAGL is a World bank-funded regional project for agriculture development in Eastern DRC, covering two provinces, namely South-Kivu and Tanganyika. This data was collected under the cassava value chain component through which the project reached thousands of cassava producers.
DOI: 10.6084/m9.figshare.24441163
title: Supplementary Material for: CureGN Pathology Classification and Core Scoring Criteria, Reproducibility, and Clinicopathologic Correlations

description: Introduction: CureGN is an observational cohort study of patients with minimal change disease (MCD), focal segmental glomerulosclerosis (FSGS), membranous nephropathy (MN), or IgA nephropathy (IgAN). We developed a conventional, consensus-based scoring system to document pathologic features for application across multiple pathologists and herein describe the protocol, reproducibility and correlation with clinical parameters at biopsy. Methods: Definitions were established for glomerular, tubular, interstitial and vascular lesions evaluated semi-quantitatively using digitized light microscopy slides and electron micrographs, and reported immunofluorescence. Cases with curated pathology materials as of April 2019 were scored by a randomly assigned pathologist, with at least 10% of cases scored by a second pathologist. Scoring reproducibility was assessed using Gwet’s AC1 statistic and correlations with clinical variables were performed. Results: Of 800 scored biopsies (143 MCD, 185 FSGS, 206 MN, 266 IgA), 94 were scored twice (11.8%). Of 60 pathology features, 46 (76.7%) demonstrated excellent (AC1&gt;0.8), and 12 (20.0%) had good (AC1 0.6-0.8) reproducibility. Mesangial hypercellularity scored as absent, focal or diffuse had moderate reproducibility (AC1=0.58), but good reproducibility (ACI=0.71) when scored as absent or focal vs diffuse. The percent glomeruli scored as no lesions had fair reproducibility (AC1=0.34). Strongest correlations between pathologic features and clinical characteristics at biopsy included interstitial inflammation, interstitial fibrosis and tubular atrophy with eGFR, foot process effacement with UPCR, and active crescents with hematuria. Conclusions: Most scored pathology features showed excellent reproducibility, demonstrating consistency for these features across multiple pathologists. Correlations between certain pathologic features and expected clinical characteristics show the value of this approach for future studies on clinicopathologic correlations and biomarker discovery.
DOI: 10.6084/m9.figshare.24441163.v1
title: Supplementary Material for: CureGN Pathology Classification and Core Scoring Criteria, Reproducibility, and Clinicopathologic Correlations

description: Introduction: CureGN is an observational cohort study of patients with minimal change disease (MCD), focal segmental glomerulosclerosis (FSGS), membranous nephropathy (MN), or IgA nephropathy (IgAN). We developed a conventional, consensus-based scoring system to document pathologic features for application across multiple pathologists and herein describe the protocol, reproducibility and correlation with clinical parameters at biopsy. Methods: Definitions were established for glomerular, tubular, interstitial and vascular lesions evaluated semi-quantitatively using digitized light microscopy slides and electron micrographs, and reported immunofluorescence. Cases with curated pathology materials as of April 2019 were scored by a randomly assigned pathologist, with at least 10% of cases scored by a second pathologist. Scoring reproducibility was assessed using Gwet’s AC1 statistic and correlations with clinical variables were performed. Results: Of 800 scored biopsies (143 MCD, 185 FSGS, 206 MN, 266 IgA), 94 were scored twice (11.8%). Of 60 pathology features, 46 (76.7%) demonstrated excellent (AC1&gt;0.8), and 12 (20.0%) had good (AC1 0.6-0.8) reproducibility. Mesangial hypercellularity scored as absent, focal or diffuse had moderate reproducibility (AC1=0.58), but good reproducibility (ACI=0.71) when scored as absent or focal vs diffuse. The percent glomeruli scored as no lesions had fair reproducibility (AC1=0.34). Strongest correlations between pathologic features and clinical characteristics at biopsy included interstitial inflammation, interstitial fibrosis and tubular atrophy with eGFR, foot process effacement with UPCR, and active crescents with hematuria. Conclusions: Most scored pathology features showed excellent reproducibility, demonstrating consistency for these features across multiple pathologists. Correlations between certain pathologic features and expected clinical characteristics show the value of this approach for future studies on clinicopathologic correlations and biomarker discovery.
DOI: 10.25345/c59882z3x
title: MassIVE MSV000093458 - GNPS - LC-MSe Data from the Berries and Roots of 60 Panax ginseng Genotypes
title: LC-MSe data acquired from the berry and root extracts of 60 different Panax ginseng genotypes, grown in an identical research farm. Details will be updated when the manuscript is published.
DOI: 10.5517/ccdc.csd.cc2c7dhj
title: CCDC 2181857: Experimental Crystal Structure Determination

description: Related Article: Arimalai Dinakararaja Samyuktha, Kannatt Radhakrishnan Ethiraj, Ponnusamy Shanmugam|2023|New J.Chem.|47|20818|doi:10.1039/D3NJ03766E
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2d5cjh
title: CCDC 2209696: Experimental Crystal Structure Determination

description: Related Article: Vincent Ming-Yau Leung, Hong-Chai Fabio Wong, Chun-Man Pook, Ying-Lung Steve Tse, Ying-Yeung Yeung|2023|Chemical Science|14|12684|doi:10.1039/D3SC03081D
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2f3g56
title: CCDC 2237647: Experimental Crystal Structure Determination

description: Related Article: Andressa Lunardi, Tanize Bortolotto, Camila Nunes Cechin, Natália de Freitas Daudt, Melina de Azevedo Mello, Sailer S. dos Santos, Roberta Cargnelutti, Ernesto Schulz Lang, Bárbara Tirloni|2023|Dalton Trans.|52|16841|doi:10.1039/D3DT03094F
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2fd5gh
title: CCDC 2246026: Experimental Crystal Structure Determination

description: Related Article: Pandi Muthukumar, Gunasekaran Arunkumar, Mehboobali Pannipara, Abdullah G. Al-Sehemi, Dohyun Moon, Savarimuthu Philip Anthony|2023|New J.Chem.|47|20831|doi:10.1039/D3NJ03660J
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2fvff5
title: CCDC 2259727: Experimental Crystal Structure Determination

description: Related Article: Meng Wang, Simin Li, Xiongkai Tang, Dongjie Zuo, Yanyuan Jia, Shuo Guo, Zong-Jie Guan, Hui Shen|2023|Phys.Chem.Chem.Phys.(PCCP)|25|30373|doi:10.1039/D3CP02736H
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.6084/m9.figshare.24612204
title: Supplementary Material for: Sampling from extracorporeal circuit: a step forward for dose monitoring in CRRT

description: Introduction: Continuous renal replacement therapies (CRRT) require constant monitoring and periodic treatment readjustments, being applied to highly complex patients, with rapidly changing clinical needs. To promote precision medicine in the field of renal replacement therapy and encourage dynamic prescription, the Acute Dialysis Quality Initiative (ADQI) recommends periodically measuring the solutes extracorporeal clearance with the aim of assessing the current treatment delivery and the gap from the therapeutic prescription (often intended as effluent dose). To perform this procedure, it is therefore necessary to obtain blood and effluent samples from the extracorporeal circuit to measure the concentrations of a target solute (usually represented by urea) prefilter, post-filter and in the effluent line. However, samples must be collected simultaneously from the extracorporeal circuit ports, with the same suction flow at unknown rate. Methods: The proposed study takes the first steps toward identifying the technical factors that should be considered in determining the optimal suction rate to collect samples from the extracorporeal circuit to measure the extracorporeal clearance for a specific solute. Results: The results obtained identify the low suction rate (i.e., 1 ml/min) as an ideal parameter for an adequate sampling method. Low velocities do not perturb the external circulation system and ensure stable prevailing pressures in the circuit. Higher velocities can be allowed only with blood flows above 120 ml/min preferably in conditions of appropriate filtration fraction. Discussion/Conclusions: The specific value of aspiration flow rate must be proportioned to the prescription of CRRT treatments set by the clinician.
DOI: 10.6084/m9.figshare.24612204.v1
title: Supplementary Material for: Sampling from extracorporeal circuit: a step forward for dose monitoring in CRRT

description: Introduction: Continuous renal replacement therapies (CRRT) require constant monitoring and periodic treatment readjustments, being applied to highly complex patients, with rapidly changing clinical needs. To promote precision medicine in the field of renal replacement therapy and encourage dynamic prescription, the Acute Dialysis Quality Initiative (ADQI) recommends periodically measuring the solutes extracorporeal clearance with the aim of assessing the current treatment delivery and the gap from the therapeutic prescription (often intended as effluent dose). To perform this procedure, it is therefore necessary to obtain blood and effluent samples from the extracorporeal circuit to measure the concentrations of a target solute (usually represented by urea) prefilter, post-filter and in the effluent line. However, samples must be collected simultaneously from the extracorporeal circuit ports, with the same suction flow at unknown rate. Methods: The proposed study takes the first steps toward identifying the technical factors that should be considered in determining the optimal suction rate to collect samples from the extracorporeal circuit to measure the extracorporeal clearance for a specific solute. Results: The results obtained identify the low suction rate (i.e., 1 ml/min) as an ideal parameter for an adequate sampling method. Low velocities do not perturb the external circulation system and ensure stable prevailing pressures in the circuit. Higher velocities can be allowed only with blood flows above 120 ml/min preferably in conditions of appropriate filtration fraction. Discussion/Conclusions: The specific value of aspiration flow rate must be proportioned to the prescription of CRRT treatments set by the clinician.
DOI: 10.6084/m9.figshare.24612207
title: Supplementary Material for: Sampling from extracorporeal circuit: a step forward for dose monitoring in CRRT

description: Introduction: Continuous renal replacement therapies (CRRT) require constant monitoring and periodic treatment readjustments, being applied to highly complex patients, with rapidly changing clinical needs. To promote precision medicine in the field of renal replacement therapy and encourage dynamic prescription, the Acute Dialysis Quality Initiative (ADQI) recommends periodically measuring the solutes extracorporeal clearance with the aim of assessing the current treatment delivery and the gap from the therapeutic prescription (often intended as effluent dose). To perform this procedure, it is therefore necessary to obtain blood and effluent samples from the extracorporeal circuit to measure the concentrations of a target solute (usually represented by urea) prefilter, post-filter and in the effluent line. However, samples must be collected simultaneously from the extracorporeal circuit ports, with the same suction flow at unknown rate. Methods: The proposed study takes the first steps toward identifying the technical factors that should be considered in determining the optimal suction rate to collect samples from the extracorporeal circuit to measure the extracorporeal clearance for a specific solute. Results: The results obtained identify the low suction rate (i.e., 1 ml/min) as an ideal parameter for an adequate sampling method. Low velocities do not perturb the external circulation system and ensure stable prevailing pressures in the circuit. Higher velocities can be allowed only with blood flows above 120 ml/min preferably in conditions of appropriate filtration fraction. Discussion/Conclusions: The specific value of aspiration flow rate must be proportioned to the prescription of CRRT treatments set by the clinician.
DOI: 10.6084/m9.figshare.24612207.v1
title: Supplementary Material for: Sampling from extracorporeal circuit: a step forward for dose monitoring in CRRT

description: Introduction: Continuous renal replacement therapies (CRRT) require constant monitoring and periodic treatment readjustments, being applied to highly complex patients, with rapidly changing clinical needs. To promote precision medicine in the field of renal replacement therapy and encourage dynamic prescription, the Acute Dialysis Quality Initiative (ADQI) recommends periodically measuring the solutes extracorporeal clearance with the aim of assessing the current treatment delivery and the gap from the therapeutic prescription (often intended as effluent dose). To perform this procedure, it is therefore necessary to obtain blood and effluent samples from the extracorporeal circuit to measure the concentrations of a target solute (usually represented by urea) prefilter, post-filter and in the effluent line. However, samples must be collected simultaneously from the extracorporeal circuit ports, with the same suction flow at unknown rate. Methods: The proposed study takes the first steps toward identifying the technical factors that should be considered in determining the optimal suction rate to collect samples from the extracorporeal circuit to measure the extracorporeal clearance for a specific solute. Results: The results obtained identify the low suction rate (i.e., 1 ml/min) as an ideal parameter for an adequate sampling method. Low velocities do not perturb the external circulation system and ensure stable prevailing pressures in the circuit. Higher velocities can be allowed only with blood flows above 120 ml/min preferably in conditions of appropriate filtration fraction. Discussion/Conclusions: The specific value of aspiration flow rate must be proportioned to the prescription of CRRT treatments set by the clinician.
DOI: 10.6084/m9.figshare.24612213
title: Supplementary Material for: Sampling from extracorporeal circuit: a step forward for dose monitoring in CRRT

description: Introduction: Continuous renal replacement therapies (CRRT) require constant monitoring and periodic treatment readjustments, being applied to highly complex patients, with rapidly changing clinical needs. To promote precision medicine in the field of renal replacement therapy and encourage dynamic prescription, the Acute Dialysis Quality Initiative (ADQI) recommends periodically measuring the solutes extracorporeal clearance with the aim of assessing the current treatment delivery and the gap from the therapeutic prescription (often intended as effluent dose). To perform this procedure, it is therefore necessary to obtain blood and effluent samples from the extracorporeal circuit to measure the concentrations of a target solute (usually represented by urea) prefilter, post-filter and in the effluent line. However, samples must be collected simultaneously from the extracorporeal circuit ports, with the same suction flow at unknown rate. Methods: The proposed study takes the first steps toward identifying the technical factors that should be considered in determining the optimal suction rate to collect samples from the extracorporeal circuit to measure the extracorporeal clearance for a specific solute. Results: The results obtained identify the low suction rate (i.e., 1 ml/min) as an ideal parameter for an adequate sampling method. Low velocities do not perturb the external circulation system and ensure stable prevailing pressures in the circuit. Higher velocities can be allowed only with blood flows above 120 ml/min preferably in conditions of appropriate filtration fraction. Discussion/Conclusions: The specific value of aspiration flow rate must be proportioned to the prescription of CRRT treatments set by the clinician.
DOI: 10.6084/m9.figshare.24612213.v1
title: Supplementary Material for: Sampling from extracorporeal circuit: a step forward for dose monitoring in CRRT

description: Introduction: Continuous renal replacement therapies (CRRT) require constant monitoring and periodic treatment readjustments, being applied to highly complex patients, with rapidly changing clinical needs. To promote precision medicine in the field of renal replacement therapy and encourage dynamic prescription, the Acute Dialysis Quality Initiative (ADQI) recommends periodically measuring the solutes extracorporeal clearance with the aim of assessing the current treatment delivery and the gap from the therapeutic prescription (often intended as effluent dose). To perform this procedure, it is therefore necessary to obtain blood and effluent samples from the extracorporeal circuit to measure the concentrations of a target solute (usually represented by urea) prefilter, post-filter and in the effluent line. However, samples must be collected simultaneously from the extracorporeal circuit ports, with the same suction flow at unknown rate. Methods: The proposed study takes the first steps toward identifying the technical factors that should be considered in determining the optimal suction rate to collect samples from the extracorporeal circuit to measure the extracorporeal clearance for a specific solute. Results: The results obtained identify the low suction rate (i.e., 1 ml/min) as an ideal parameter for an adequate sampling method. Low velocities do not perturb the external circulation system and ensure stable prevailing pressures in the circuit. Higher velocities can be allowed only with blood flows above 120 ml/min preferably in conditions of appropriate filtration fraction. Discussion/Conclusions: The specific value of aspiration flow rate must be proportioned to the prescription of CRRT treatments set by the clinician.
DOI: 10.6084/m9.figshare.24612225
title: Supplementary Material for: Sampling from extracorporeal circuit: a step forward for dose monitoring in CRRT

description: Introduction: Continuous renal replacement therapies (CRRT) require constant monitoring and periodic treatment readjustments, being applied to highly complex patients, with rapidly changing clinical needs. To promote precision medicine in the field of renal replacement therapy and encourage dynamic prescription, the Acute Dialysis Quality Initiative (ADQI) recommends periodically measuring the solutes extracorporeal clearance with the aim of assessing the current treatment delivery and the gap from the therapeutic prescription (often intended as effluent dose). To perform this procedure, it is therefore necessary to obtain blood and effluent samples from the extracorporeal circuit to measure the concentrations of a target solute (usually represented by urea) prefilter, post-filter and in the effluent line. However, samples must be collected simultaneously from the extracorporeal circuit ports, with the same suction flow at unknown rate. Methods: The proposed study takes the first steps toward identifying the technical factors that should be considered in determining the optimal suction rate to collect samples from the extracorporeal circuit to measure the extracorporeal clearance for a specific solute. Results: The results obtained identify the low suction rate (i.e., 1 ml/min) as an ideal parameter for an adequate sampling method. Low velocities do not perturb the external circulation system and ensure stable prevailing pressures in the circuit. Higher velocities can be allowed only with blood flows above 120 ml/min preferably in conditions of appropriate filtration fraction. Discussion/Conclusions: The specific value of aspiration flow rate must be proportioned to the prescription of CRRT treatments set by the clinician.