cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q2k35xcx
title: BindingDB Entry 50003501: Novel cyclic compounds as potent phosphodiesterase 4 inhibitors.

description: Small molecule binding data for protein Phosphodiesterase 4, Uniprot A0A140VJR0, P27815, Q07343, Q08493, Q08499, and X5DNX5
DOI: 10.7270/q2fb55nk
title: BindingDB Entry 50003502: Metabolites of the angiotensin II antagonist tasosartan: the importance of a second acidic group.

description: Small molecule binding data for protein Angiotensin II receptor (AT-1) type-1, Uniprot P25095 and P29089
DOI: 10.7270/q29k4dz9
title: BindingDB Entry 50003503: Quantitative structure-activity relationships of 2, 4-diamino-5-(2-X-benzyl)pyrimidines versus bacterial and avian dihydrofolate reductase.

description: Small molecule binding data for protein Dihydrofolate reductase, Uniprot P00378 and P00381
DOI: 10.7270/q2251mzb
title: BindingDB Entry 50003505: Synthesis and antitumor activity of new glycosides of epipodophyllotoxin, analogues of etoposide, and NK 611.

description: Small molecule binding data for protein DNA topoisomerase II, Uniprot P11388 and Q02880
DOI: 10.7270/q25x2cpr
title: BindingDB Entry 50003504: Design of new topoisomerase II inhibitors based upon a quinobenzoxazine self-assembly model.

description: Small molecule binding data for protein DNA topoisomerase II, Uniprot P11388 and Q02880
DOI: 10.7270/q2xd14f0
title: BindingDB Entry 50003506: Three-dimensional quantitative structure-activity relationship study of the cannabimimetic (aminoalkyl)indoles using comparative molecular field analysis.

description: Small molecule binding data for protein Cannabinoid receptor, Uniprot P20272
DOI: 10.7270/q2sn0cq8
title: BindingDB Entry 50003507: Synthesis of 7-benzylamino-6-chloro-2-piperazino-4-pyrrolidinopteridine and novel derivatives free of positional isomers. Potent inhibitors of cAMP-specific phosphodiesterase and of malignant tumor cell growth.

description: Small molecule binding data for protein Phosphodiesterase 4, Uniprot A0A140VJR0, P27815, Q07343, Q08493, Q08499, and X5DNX5
DOI: 10.7270/q2nv9n0d
title: BindingDB Entry 50003508: Methoxy-substituted 3-formyl-2-phenylindoles inhibit tubulin polymerization.

description: Small molecule binding data for protein Similar to alpha-tubulin isoform 1, Uniprot Q862L2
DOI: 10.7270/q2j38w9f
title: BindingDB Entry 50003509: N-(2-Benzoylphenyl)-L-tyrosine PPARgamma agonists. 2. Structure-activity relationship and optimization of the phenyl alkyl ether moiety.

description: Small molecule binding data for protein Peroxisome proliferator-activated receptor, Uniprot F1D8S4, P37231, and Q07869
DOI: 10.7270/q28p6383
title: BindingDB Entry 50003511: Design and synthesis of a series of 6-substituted-2-pyridinylmethylamine derivatives as novel, high-affinity, selective agonists at 5-HT1A receptors.

description: Small molecule binding data for protein Serotonin 1 (5-HT1) receptor, Uniprot P19327
DOI: 10.7270/q2db84mj
title: BindingDB Entry 50003510: N-(2-Benzoylphenyl)-L-tyrosine PPARgamma agonists. 3. Structure-activity relationship and optimization of the N-aryl substituent.

description: Small molecule binding data for protein Peroxisome proliferator-activated receptor, Uniprot P37231
DOI: 10.7270/q24x5bjc
title: BindingDB Entry 50003512: Novel potent nonpeptide aminopeptidase N inhibitors with a cyclic imide skeleton.

description: Small molecule binding data for protein Aminopeptidase and Dipeptidyl peptidase II and dipeptidyl peptidase IV (DPP2 and DPP4), Uniprot A0A024RC61, P15144, and P27487
DOI: 10.7270/q2154ksh
title: BindingDB Entry 50003513: Mapping the melatonin receptor. 5. Melatonin agonists and antagonists derived from tetrahydrocyclopent[b]indoles, tetrahydrocarbazoles and hexahydrocyclohept[b]indoles.

description: Small molecule binding data for protein Melatonin receptor type 1C, Uniprot P49288
DOI: 10.7270/q2wd439m
title: BindingDB Entry 50003514: 1,4-Cyclohexanecarboxylates: potent and selective inhibitors of phosophodiesterase 4 for the treatment of asthma.

description: Small molecule binding data for protein Phosphodiesterase 4 and cAMP-specific 3',5'-cyclic phosphodiesterase 4C, Uniprot A0A140VJR0, P14644, P27815, Q07343, Q08493, Q08499, and X5DNX5
DOI: 10.7270/q2mw2kv5
title: BindingDB Entry 50003516: Synthesis and biological activity of chimeric structures derived from the cytotoxic natural compounds dolastatin 10 and dolastatin 15.

description: Small molecule binding data for protein Similar to alpha-tubulin isoform 1, Uniprot Q862L2
DOI: 10.7270/q2rn3bkw
title: BindingDB Entry 50003515: Antitumor agents. 181. Synthesis and biological evaluation of 6,7,2',3',4'-substituted-1,2,3,4-tetrahydro-2-phenyl-4-quinolones as a new class of antimitotic antitumor agents.

description: Small molecule binding data for protein Similar to alpha-tubulin isoform 1, Uniprot Q862L2
DOI: 10.7270/q2h41v5m
title: BindingDB Entry 50003517: Synthesis, calcium mobilizing, and physicochemical properties of D-chiro-inositol 1,3,4,6-tetrakisphosphate, a novel and potent ligand at the D-myo-inositol 1,4,5-trisphosphate receptor.

description: Small molecule binding data for protein Inositol 1,4,5-trisphosphate receptor type 2, Uniprot Q14571
DOI: 10.7270/q2cf9st6
title: BindingDB Entry 50003518: Structure-antiviral activity relationship in the series of pyrimidine and purine N-[2-(2-phosphonomethoxy)ethyl] nucleotide analogues. 1. Derivatives substituted at the carbon atoms of the base.

description: Small molecule binding data for protein Thymidine kinase, Uniprot P06479 and Q6QCL9
DOI: 10.7270/q23x89cj
title: BindingDB Entry 50003520: Novel and potent 6-chloro-3-pyridinyl ligands for the alpha4beta2 neuronal nicotinic acetylcholine receptor.

description: Small molecule binding data for protein Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit, Uniprot P09483 and P12390
DOI: 10.7270/q27p924q
title: BindingDB Entry 50003519: A peptide agonist acts by occupation of a monomeric G protein-coupled receptor: dual sites of covalent attachment to domains near TM1 and TM7 of the same molecule make biologically significant domain-swapped dimerization unlikely.

description: Small molecule binding data for protein Cholecystokinin receptor, Uniprot P32238 and P32239
DOI: 10.7270/q2057jn4
title: BindingDB Entry 50003521: 2-Amino-4-benzyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridines: novel selective beta3-adrenoceptor agonists.

description: Small molecule binding data for protein Adrenergic receptor and Beta-2 adrenergic receptor and beta-3 adrenergic receptor, Uniprot A8KAG8, P07550, P08588, P13945, and X5DQM5
DOI: 10.7270/q2vd7257
title: BindingDB Entry 50003522: Synthesis and serotonergic activity of substituted 2, N-benzylcarboxamido-5-(2-ethyl-1-dioxoimidazolidinyl)-N, N-dimethyltryptamine derivatives: novel antagonists for the vascular 5-HT(1B)-like receptor.

description: Small molecule binding data for protein Serotonin (5-HT) receptor, Serotonin 1 (5-HT1) receptor, and Serotonin receptor 2a and 2c (5HT2A and 5HT2C), Uniprot P08909, P19327, and P28221
DOI: 10.7270/q2kw5jr7
title: BindingDB Entry 50003524: 2-(2-Phenylcyclopropyl)imidazolines: reversed enantioselective interaction at I(1) and I(2) imidazoline receptors.

description: Small molecule binding data for protein Adrenergic receptor alpha-2, Imidazoline I2-receptor, and Nischarin, Uniprot P19328, P21397, P22086, P27338, Q53YE7, and Q9Y2I1
DOI: 10.7270/q2qn69gz
title: BindingDB Entry 50003523: Anticonvulsant and sodium channel-blocking properties of novel 10,11-dihydro-5H-dibenz[b,f]azepine-5-carboxamide derivatives.

description: Small molecule binding data for protein Sodium channel protein type I I alpha subunit, Uniprot P04774, P04775, and P08104
DOI: 10.7270/q2g73hg0
title: BindingDB Entry 50003525: (R)-3,3,3-Trifluoro-2-hydroxy-2-methylpropionamides are orally active inhibitors of pyruvate dehydrogenase kinase.

description: Small molecule binding data for protein Pyruvate dehydrogenase kinase, Uniprot A4D1H4, Q15118, Q15119, Q15120, and Q16654
DOI: 10.7270/q26q210w
title: BindingDB Entry 50003527: Structure-activity relationships in 1,4-benzodioxan-related compounds. 6. Role of the dioxane unit on selectivity for alpha(1)-adrenoreceptor subtypes.

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 1A, 5-hydroxytryptamine receptor 2A, Adrenergic receptor, Adrenergic receptor alpha-2, and Dopamine D2 receptor and Serotonin 2a receptor (D2 and 5HT2a), Uniprot B0ZBE0, P08908, P14842, P19328, P22086, P25100, P35348, P35368, P61169, and Q5ZGX3
DOI: 10.7270/q2bg2rr8
title: BindingDB Entry 50003526: Conformationally constrained butyrophenones with mixed dopaminergic (D(2)) and serotoninergic (5-HT(2A), 5-HT(2C)) affinities: synthesis, pharmacology, 3D-QSAR, and molecular modeling of (aminoalkyl)benzo- and -thienocycloalkanones as putative atypical antipsychotics.

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 2A, 5-hydroxytryptamine receptor 2C, Dopamine D2 receptor and Serotonin 2a receptor (D2 and 5HT2a), and Dopamine receptors; D1 & D2, Uniprot P14842, P18901, P28335, and P61169
DOI: 10.7270/q22z1885
title: BindingDB Entry 50003528: Synthesis and histone deacetylase inhibitory activity of new benzamide derivatives.

description: Small molecule binding data for protein Histone deacetylase, Uniprot A0A024QZ26, O15379, P56524, Q13547, Q6IT96, Q8WUI4, Q92769, Q969S8, Q96DB2, Q9BY41, Q9UBN7, Q9UKV0, and Q9UQL6
DOI: 10.7270/q2tf012v
title: BindingDB Entry 50003530: WB 4101-related compounds. 2. Role of the ethylene chain separating amine and phenoxy units on the affinity for alpha(1)-adrenoreceptor subtypes and 5-HT(1A) receptors.

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 1A, Adrenergic receptor, Adrenergic receptor alpha-2, Dopamine D2 receptor and Serotonin 2a receptor (D2 and 5HT2a), and Serotonin 2 (5-HT2) receptor, Uniprot B0ZBE0, P08908, P08909, P14842, P19328, P22086, P25100, P30994, P35348, P35368, P61169, and Q5ZGX3
DOI: 10.7270/q2z60rss
title: BindingDB Entry 50003529: Antitumor agents. 196. Substituted 2-thienyl-1,8-naphthyridin-4-ones: their synthesis, cytotoxicity, and inhibition of tubulin polymerization.

description: Small molecule binding data for protein Similar to alpha-tubulin isoform 1, Uniprot Q862L2
DOI: 10.7270/q2pn98c1
title: BindingDB Entry 50003531: Angiotensin II analogues encompassing 5,9- and 5,10-fused thiazabicycloalkane tripeptide mimetics.

description: Small molecule binding data for protein Angiotensin II receptor (AT-1) type-1, Uniprot P25095 and P29089
DOI: 10.7270/q2f76g95
title: BindingDB Entry 50003533: Alpha(2) adrenoceptor agonists as potential analgesic agents. 1. (Imidazolylmethyl)oxazoles and -thiazoles.

description: Small molecule binding data for protein Adrenergic receptor alpha-2, Uniprot P19328 and P22086
DOI: 10.7270/q2k0770f
title: BindingDB Entry 50003532: Improving the nicotinic pharmacophore with a series of (Isoxazole)methylene-1-azacyclic compounds: synthesis, structure-activity relationship, and molecular modeling.

description: Small molecule binding data for protein Muscarinic acetylcholine receptor, Uniprot P08482, P08483, P08485, P08911, and P10980
DOI: 10.7270/q29g5qj0
title: BindingDB Entry 50003534: Vasorelaxation by new hybrid compounds containing dihydropyridine and pinacidil-like moieties.

description: Small molecule binding data for protein Voltage-dependent L-type calcium channel subunit alpha-1S, Uniprot Q02485
DOI: 10.7270/q25q4zt8
title: BindingDB Entry 50003535: Synthesis and structure-activity relationships of new 1, 3-disubstituted cyclohexanes as structurally rigid leukotriene B(4) receptor antagonists.

description: Small molecule binding data for protein Leukotriene B4 receptor and Leukotriene B4 receptor 2, Uniprot Q15722 and Q9NPC1
DOI: 10.7270/q21z474s
title: BindingDB Entry 50003537: Three-dimensional quantitative structure-activity relationship analyses using comparative molecular field analysis and comparative molecular similarity indices analysis to elucidate selectivity differences of inhibitors binding to trypsin, thrombin, and factor Xa.

description: Small molecule binding data for protein Thrombin, Thrombin and coagulation factor X, and Trypsin I, Uniprot P00735, P00742, P00760, and Q5JVE7
DOI: 10.7270/q2x63qpv
title: BindingDB Entry 50003538: Tetrahydrobenzindoles: selective antagonists of the 5-HT7 receptor.

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 1A, 5-hydroxytryptamine receptor 6, 5-hydroxytryptamine receptor 7, Dopamine D2 receptor and Serotonin 2a receptor (D2 and 5HT2a), Serotonin 2 (5-HT2) receptor, and Serotonin 4 (5-HT4) receptor, Uniprot O70528, P08908, P08909, P14842, P30994, P34969, P50406, P61169, and Q5ZGX3
DOI: 10.7270/q2sf2zxp
title: BindingDB Entry 50003539: Syntheses and biological activities of rebeccamycin analogues. Introduction of a halogenoacetyl substituent.

description: Small molecule binding data for protein Protein kinase C (PKC), Uniprot A0A024R328, L7RSM7, L7RTI5, O94806, P05129, P05771, P17252, P24723, P41743, Q02156, Q04759, Q05513, Q05655, and Q15139
DOI: 10.7270/q2ns0xmp
title: BindingDB Entry 50003540: Bicyclic tripeptide mimetics with reverse turn inducing properties.

description: Small molecule binding data for protein Angiotensin II receptor (AT-1) type-1, Uniprot P25095 and P29089
DOI: 10.7270/q2d79f4b
title: BindingDB Entry 50003542: Acquisition of high-affinity, SH2-targeted ligands via a spatially focused library.

description: Small molecule binding data for protein Growth factor receptor-bound protein 2, SRC, and Tyrosine-protein kinase Fyn, Uniprot A0A0S2Z3Y8, B0LPF3, P06239, P06241, and P62993
DOI: 10.7270/q2j105wn
title: BindingDB Entry 50003541: Discovery of 6-oxo-3-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)-1(6H)- pyridazinebutanoic acid (FK 838): a novel non-xanthine adenosine A1 receptor antagonist with potent diuretic activity.

description: Small molecule binding data for protein Adenosine A2 receptor, Adenosine receptor, and Adenosine receptor A1, Uniprot P25099, P29276, P30542, and P30543
DOI: 10.7270/q20z760d
title: BindingDB Entry 50003545: Synthesis and in vitro pharmacology of a series of new chiral histamine H3-receptor ligands: 2-(R and S)-Amino-3-(1H-imidazol-4(5)-yl)propyl ether derivatives.

description: Small molecule binding data for protein Histamine H3 receptor, Uniprot Q9QYN8
DOI: 10.7270/q24q7xpw
title: BindingDB Entry 50003544: Characterization of the binding site of the histamine H3 receptor. 1. Various approaches to the synthesis of 2-(1H-imidazol-4-yl)cyclopropylamine and histaminergic activity of (1R,2R)- and (1S,2S)-2-(1H-imidazol-4-yl)-cyclopropylamine.

description: Small molecule binding data for protein Histamine H3 receptor, Uniprot Q9QYN8
DOI: 10.7270/q28g8pdm
title: BindingDB Entry 50003543: Melatonergic properties of the (+)- and (-)-enantiomers of N-(4-methoxy-2,3-dihydro-1H-phenalen-2-yl)amide derivatives.

description: Small molecule binding data for protein Melatonin receptor type 1C, Uniprot P49288
DOI: 10.7270/q2w66ph1
title: BindingDB Entry 50003546: Laurenditerpenol, a new diterpene from the tropical marine alga Laurenciaintricata that potently inhibits HIF-1 mediated hypoxic signaling in breast tumor cells.

description: Small molecule binding data for protein Hypoxia inducible factors; HIF-1-alpha, HIF-2-alpha, Uniprot D0VY79, Q16665, and Q99814
DOI: 10.7270/q2ms3whr
title: BindingDB Entry 50003548: Novel derivatives of 2-pyridinemethylamine as selective, potent, and orally active agonists at 5-HT1A receptors.

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 1A, Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor, Dopamine D2 receptor and Serotonin 2a receptor (D2 and 5HT2a), and Serotonin 1 (5-HT1) receptor, Uniprot P08908, P15823, P19327, P23944, P43140, P61169, and Q5ZGX3
DOI: 10.7270/q2rj4n61
title: BindingDB Entry 50003547: Comparative molecular field analysis of hydantoin binding to the neuronal voltage-dependent sodium channel.

description: Small molecule binding data for protein Sodium channel protein type I I alpha subunit, Uniprot P04774, P04775, and P08104
DOI: 10.7270/q2h134r8
title: BindingDB Entry 50003549: Novel antiarthritic agents with 1,2-isothiazolidine-1,1-dioxide (gamma-sultam) skeleton: cytokine suppressive dual inhibitors of cyclooxygenase-2 and 5-lipoxygenase.

description: Small molecule binding data for protein Cyclooxygenase, Uniprot P35355 and Q63921
DOI: 10.7270/q27h1n97
title: BindingDB Entry 50003551: A 3D-QSAR study on the structural requirements for binding to CB(1) and CB(2) cannabinoid receptors.

description: Small molecule binding data for protein Cannabinoid receptor 1 and Cannabinoid receptor 2, Uniprot A0A024RAH7, P21554, P34972, and S5TLS4
DOI: 10.7270/q2c82d1z
title: BindingDB Entry 50003550: Anilides of (R)-trifluoro-2-hydroxy-2-methylpropionic acid as inhibitors of pyruvate dehydrogenase kinase.

description: Small molecule binding data for protein Pyruvate dehydrogenase kinase, Uniprot A4D1H4, Q15118, Q15119, Q15120, and Q16654
DOI: 10.7270/q23r0wmz
title: BindingDB Entry 50003552: A rapid computational method for lead evolution: description and application to alpha(1)-adrenergic antagonists.

description: Small molecule binding data for protein Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor, Uniprot P15823, P23944, and P43140
DOI: 10.7270/q2028v88
title: BindingDB Entry 50003553: Further studies on nociceptin-related peptides: discovery of a new chemical template with antagonist activity on the nociceptin receptor.

description: Small molecule binding data for protein Nociceptin/Orphanin FQ, NOP receptor, Uniprot P35377 and Q542U1
DOI: 10.7270/q2v98btd
title: BindingDB Entry 50003554: 3-(Hydroxymethyl)-bearing phosphatidylinositol ether lipid analogues and carbonate surrogates block PI3-K, Akt, and cancer cell growth.

description: Small molecule binding data for protein Serine/threonine-protein kinase AKT, Uniprot B0LPE5, P31749, P31751, and Q9Y243
DOI: 10.7270/q2qj7m2n
title: BindingDB Entry 50003555: GRid-INdependent descriptors (GRIND): a novel class of alignment-independent three-dimensional molecular descriptors.

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 2A and Corticosteroid-binding globulin, Uniprot P08185 and P14842
DOI: 10.7270/q2g163kf
title: BindingDB Entry 50003557: Synthesis and pharmacological characterization of [(125)I]iodomethyllycaconitine ([(125)I]iodo-MLA). A new ligand for the alpha(7) nicotinic acetylcholine receptor.

description: Small molecule binding data for protein Neuronal acetylcholine receptor, Uniprot Q05941
DOI: 10.7270/q2ks6v9g
title: BindingDB Entry 50003556: 2,7-Dioxo-2,3,4,5,6,7-hexahydro-1H-benzo[h][1,4]diazonine as a new template for the design of CCK(2) receptor antagonists.

description: Small molecule binding data for protein Cholecystokinin receptor, Uniprot P56481 and Q3ZB46
DOI: 10.7270/q26h4m5v
title: BindingDB Entry 50003559: Synthesis and SAR of new 5-phenyl-3-ureido-1,5-benzodiazepines as cholecystokinin-B receptor antagonists.

description: Small molecule binding data for protein Cholecystokinin receptor, Uniprot P30551, P30553, and P32239
DOI: 10.7270/q2b85bvq
title: BindingDB Entry 50003558: Secondary amides of (R)-3,3,3-trifluoro-2-hydroxy-2-methylpropionic acid as inhibitors of pyruvate dehydrogenase kinase.

description: Small molecule binding data for protein Pyruvate dehydrogenase kinase and [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial, Uniprot B5DFI9, O54937, Q63065, and Q64536
DOI: 10.7270/q22v2jt0
title: BindingDB Entry 50003560: Structure-based design of novel bicyclic nonpeptide inhibitors for the src SH2 domain.

description: Small molecule binding data for protein Calmodulin/Proto-oncogene tyrosine-protein kinase Src, Uniprot P12931
DOI: 10.7270/q2z322cv
title: BindingDB Entry 50003561: Discovery of potent cyclic pseudopeptide human tachykinin NK-2 receptor antagonists.

description: Small molecule binding data for protein Neurokinin 2 receptor, Uniprot P21452
DOI: 10.7270/q2pk0jwz
title: BindingDB Entry 50003563: 2D QSAR modeling and preliminary database searching for dopamine transporter inhibitors using genetic algorithm variable selection of Molconn Z descriptors.

description: Small molecule binding data for protein Sodium-dependent dopamine transporter, Uniprot P23977
DOI: 10.7270/q2tb19n4
title: BindingDB Entry 50003562: Adenosine analogues as inhibitors of Trypanosoma brucei phosphoglycerate kinase: elucidation of a novel binding mode for a 2-amino-N(6)-substituted adenosine.

description: Small molecule binding data for protein Phosphoglycerate kinase 1, Uniprot P00558 and V9HWF4
DOI: 10.7270/q2js9t53
title: BindingDB Entry 50003565: 6-Alkylamino- and 2,3-dihydro-3'-methoxy-2-phenyl-4-quinazolinones and related compounds: their synthesis, cytotoxicity, and inhibition of tubulin polymerization.

description: Small molecule binding data for protein Similar to alpha-tubulin isoform 1, Uniprot Q862L2
DOI: 10.7270/q2f192f2
title: BindingDB Entry 50003566: Solid-phase synthesis and biological evaluation of a combinatorial library of philanthotoxin analogues.

description: Small molecule binding data for protein Acetylcholine receptor protein alpha chain/beta chain/delta chain /gamma chain, Uniprot P02708, P07510, P11230, and Q07001
DOI: 10.7270/q29889rs
title: BindingDB Entry 50003567: Synthesis, (18)F-labeling, and biological evaluation of piperidyl and pyrrolidyl benzilates as in vivo ligands for muscarinic acetylcholine receptors.

description: Small molecule binding data for protein Muscarinic acetylcholine receptor, Uniprot P08482, P08483, P08485, P08911, and P10980
DOI: 10.7270/q25m68fs
title: BindingDB Entry 50003568: Synthesis, structure-activity relationships, and pharmacological profile of 9-amino-4-oxo-1-phenyl-3,4,6,7-tetrahydro[1,4]diazepino[6, 7,1-hi]indoles: discovery of potent, selective phosphodiesterase type 4 inhibitors.

description: Small molecule binding data for protein Phosphodiesterase 3, Phosphodiesterase 4, Phosphodiesterase, PDE1/PDE5, and cAMP-specific 3',5'-cyclic phosphodiesterase 4C, Uniprot A0A024RB59, A0A140VJR0, O76074, P14644, P27815, P54750, Q01064, Q07343, Q08493, Q08499, Q13370, Q14123, Q14432, and X5DNX5
DOI: 10.7270/q21v5hq2
title: BindingDB Entry 50003569: Synthesis, molecular modeling, and pharmacological testing of bis-quinolinium cyclophanes: potent, non-peptidic blockers of the apamin-sensitive Ca(2+)-activated K(+) channel.

description: Small molecule binding data for protein Small conductance calcium-activated potassium channel, Uniprot P70604, P70605, and P70606
DOI: 10.7270/q2x35161
title: BindingDB Entry 50003570: Binding and preliminary evaluation of 5-hydroxy- and 10-hydroxy-2,3, 12,12a-tetrahydro-1H-[1]benzoxepino[2,3,4-ij]isoquinolines as dopamine receptor ligands.

description: Small molecule binding data for protein Dopamine D2 receptor and Serotonin 2a receptor (D2 and 5HT2a) and Dopamine receptors; D1 & D2, Uniprot P18901 and P61169
DOI: 10.7270/q2sb48g9
title: BindingDB Entry 50003571: 3D-QSAR CoMFA study on imidazolinergic I(2) ligands: a significant model through a combined exploration of structural diversity and methodology.

description: Small molecule binding data for protein Nischarin, Uniprot Q9Y2I1
DOI: 10.7270/q2nk3hrk
title: BindingDB Entry 50003572: Novel and selective calcitonin-inducing agents.

description: Small molecule binding data for protein Phosphodiesterase 4, Uniprot A0A140VJR0, P27815, Q07343, Q08493, Q08499, and X5DNX5
DOI: 10.7270/q2d221c4
title: BindingDB Entry 50003574: 2-amino-2-oxazolines as subtype selective alpha(2) adrenoceptor agonists.

description: Small molecule binding data for protein Adenosine receptor A1/Alpha-2A adrenergic receptor and Adrenergic receptor, Uniprot P08913, P18089, P18825, and Q4W594
DOI: 10.7270/q2ht2s2q
title: BindingDB Entry 50003573: Inhibition of protein kinase C(alpha) by dequalinium analogues: dependence on linker length and geometry.

description: Small molecule binding data for protein PKC alpha and beta-2, Uniprot L7RSM7 and P17252