cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6075/j0668ddr
title: Data from: SEEKR2: Versatile Multiscale Milestoning Utilizing the OpenMM Molecular Dynamics Engine

description: This data set contains the files necessary to recreate the results in the paper "SEEKR2: Versatile Multiscale Milestoning Utilizing the OpenMM Molecular Dynamics Engine". Specifically, the data for the host-guest, trypsin-benzamidine, and jak2-ligand6 systems are contained here, with instructions for how to compute kinetics and thermodynamics quantities, as well as convergence and plots.
description: All data were generated using SEEKR2 v2.5.1-beta, which is also required to analyze and visualize the data in this collection. Software modules and versions: SEEKR2 v2.5.1-beta Python 3.8 Numpy 1.22.3 Scipy 1.7.3 matplotlib 3.5.2
DOI: 10.6075/j0j966jf
title: Data from: Short-term variability of atmospheric helium revealed through a cryo-enrichment method

description: He/N2 observations from Scripps Pier and supplementary O2/N2, Ar/N2 and CO2 data collected in April and May 2022. Helium mole fraction measurements were made using a cryo-enrichment method and combined with O2, Ar, and CO2 data collected using the regular methods of the Scripps O2 network. Details of the dataset are provided in the associated publication and the readme file.
DOI: 10.17909/stwg-r373
title: 10.1093/mnras/stac2820

description: These are the MAST Level 3 data that represent the observations used in the Deep diving off the ‘Cosmic Cliffs’: previously hidden outflows in NGC 3324 revealed by JWST.  More details about these data sets
are given in Reiter et al. (2022; DOI:10.1093/mnras/stac2820).
DOI: 10.26179/mpee-jt93
title: 2007-08 CEAMARC-CASO VOYAGE TRACE ELEMENT SAMPLING AROUND AN ICEBERG
DOI: 10.26179/fdqh-cd64
title: Antarctic Fur Seal Populations on Heard Island Summer 1987-1988
DOI: 10.22002/jdw94-3nh81
title: Tuning methylation-dependent silencing dynamics by synthetic modulation of CpG density

description: Raw data for paper "Tuning methylation-dependent silencing dynamics by synthetic modulation of CpG density". Previously titled as "Promoter CpG content regulates DNMT-dependent silencing dynamics"
DOI: 10.6084/m9.figshare.23918391.v1
title: Supplementary Material for: Sustained Response to Ruxolitinib of Eosinophilia-Associated Myeloproliferative Neoplasm with Translocation t(8;9)(p21;p24)

description: The translocation t(8;9) produces the fusion gene PCM1-JAK2, resulting in the continuous activation of the JAK2 tyrosine kinase. Myelodysplastic/myeloproliferative neoplasms are the most common disease with t(8;9)/PCM1-JAK2. Individuals with this abnormality have similar features, and JAK2 kinase inhibitor (ruxolitinib) is an effective treatment of the condition. The long-term remission results of ruxolitinib are varied. It is important to determine the response to ruxolitinib. Here, we describe a patient who has been diagnosed with eosinophilia-associated myeloproliferative neoplasm with t(8;9)(p21;p24). This patient has achieved sustained response for &gt;1 year since the administration of ruxolitinib.
DOI: 10.6084/m9.figshare.22732195
title: Roadblocks and resistance: Digital mediation as a process of calibration among U.S. parents of adolescents

description: Research in parental mediation often focuses on how parents’ practices for managing digital media are aligned with normative expectations. However, there is less research that explores parental mediation as a process, with practices changing over time in response to barriers and challenges. To address this gap, the goal of the current study is to examine parents’ decisions around not monitoring or limiting adolescents’ media use. Based on focus group discussions and interviews with predominantly female (77%) and White (92%) parents living in five communities in the Midwestern United States, we explore parental mediation as a process in which decisions about children’s media use reflect competing individual, ideological, and structural factors. In eight focus groups (<i>n</i> = 48) and 13 follow-up interviews, we ask parents to narrate barriers to commonly suggested mediation strategies to examine how parents’ navigate factors such as efficacy, conflict, or adolescent autonomy in managing digital media use. Based on the findings, we propose that looking at barriers illustrates mediation as a process of calibration, a decision that is made and re-made as parents navigate complex and sometimes contradictory situations and expectations. <b>Prior State of Knowledge:</b> Past studies on parental mediation of digital technology define a range of strategies like restriction or monitoring and explore factors predicting whether parents use these strategies. Less research examines how parents arrive at the decision to implement normative mediation strategies. <b>Novel Contributions:</b> We propose the term calibration to explain how barriers and challenges prompt shifts in parental mediation over time. Calibration captures how parents balance competing internal and external factors, like efficacy or norms, in engaging with adolescents about digital media use. <b>Practical Implications:</b> Conceptualizing mediation as calibration may help parents develop a toolbox of strategies that can shift as needed. In addition, focusing on values like autonomy helps parents choose which mediation strategies work for their family context and which may not.
DOI: 10.6084/m9.figshare.22732195.v1
title: Roadblocks and resistance: Digital mediation as a process of calibration among U.S. parents of adolescents

description: Research in parental mediation often focuses on how parents’ practices for managing digital media are aligned with normative expectations. However, there is less research that explores parental mediation as a process, with practices changing over time in response to barriers and challenges. To address this gap, the goal of the current study is to examine parents’ decisions around not monitoring or limiting adolescents’ media use. Based on focus group discussions and interviews with predominantly female (77%) and White (92%) parents living in five communities in the Midwestern United States, we explore parental mediation as a process in which decisions about children’s media use reflect competing individual, ideological, and structural factors. In eight focus groups (<i>n</i> = 48) and 13 follow-up interviews, we ask parents to narrate barriers to commonly suggested mediation strategies to examine how parents’ navigate factors such as efficacy, conflict, or adolescent autonomy in managing digital media use. Based on the findings, we propose that looking at barriers illustrates mediation as a process of calibration, a decision that is made and re-made as parents navigate complex and sometimes contradictory situations and expectations. <b>Prior State of Knowledge:</b> Past studies on parental mediation of digital technology define a range of strategies like restriction or monitoring and explore factors predicting whether parents use these strategies. Less research examines how parents arrive at the decision to implement normative mediation strategies. <b>Novel Contributions:</b> We propose the term calibration to explain how barriers and challenges prompt shifts in parental mediation over time. Calibration captures how parents balance competing internal and external factors, like efficacy or norms, in engaging with adolescents about digital media use. <b>Practical Implications:</b> Conceptualizing mediation as calibration may help parents develop a toolbox of strategies that can shift as needed. In addition, focusing on values like autonomy helps parents choose which mediation strategies work for their family context and which may not.
DOI: 10.5519/qd.pnct7106
title: Query on the Natural History Museum Data Portal (data.nhm.ac.uk) (1 records)
DOI: 10.26179/vzhh-3x13
title: Temperature Data from the Lakes of the Vestfold Hills Antarctica
DOI: 10.26179/qbbn-ps87
title: Royal Penguins at Macquarie Island
DOI: 10.6084/m9.figshare.21617562
title: Fagopyrum genome data

description: <em>Fagopyrum</em> genome data
DOI: 10.6084/m9.figshare.23866962.v37
title: Untitled Item

description: Regridding Global CMIP6 GCMs dataset(0.5 degree)Historical dataset: 7 CMIP6 GCMs (1850-2014, ACCESS-CM2 to GFDL-ESM4)Future dataset: 7 CMIP6 GCMs and 4 SSP scenarios (2015-2100)Composition of dataset: Average temperature, Maximum temperature, Minimum temperature, Windspeed, Relative humidity, Solar radiationIf you are using our codes and dataset, please use the following references:Song, Y.H., Chung, E.S., Shahid, S., Kim, Y.J., Kim, D.K. 2023. Development of global monthly dataset of CMIP6 climate variables for estimating evapotranspiration. Scientific Data.<br>
DOI: 10.6084/m9.figshare.22309716
title: Cloning and Characterisation of a novel phosphate transporter gene <i>EcPT1</i> from <i>Eichhornia crassipes</i>

description: <i>Eichhornia crassipes</i> (Mart.) Solms can absorb nitrogen and phosphorus efficiently from water. Cloning the phosphate transporter 1 from <i>E. crassipes</i> (<i>EcPHT1</i>) and studying its characteristics can help to explain the molecular mechanism of absorption and transportation of inorganic phosphate (Pi) in <i>E. crassipes</i> and develop new genetic resources for phosphate transport to aid genetic breeding of crops with increased phosphate use efficiency. In this paper, we have used RACE method to clone the <i>EcPT1</i> with 1572 bps which encoded a polypeptide of 523 amino acids and contained 11 transmembrane regions which was the typical structure of plant PHT1. The phylogenetic analysis also showed EcPT1 was closely related to other plant PHT1s. Quantitative real-time RT-PCR (qRT-PCR) showed that the <i>EcPT1</i> expression in roots was up-regulated under low phosphorus stress . Moreover the <i>EcPT1</i> expression in leaves was suppressed after <i>E. crassipes</i> was transferred to sufficient Pi from deficient Pi. Yeast functional complementation tests showed that the <i>EcPT1</i> could complement the phosphate transport function of the Pi deficient yeast PHO84 in 175 μM Pi and make it grow best in pH = 5 or 6. All these results indicated that <i>EcPT1</i> might be a phosphate transporter gene. Its expression was different in different tissues.
DOI: 10.6084/m9.figshare.22194452
title: Genome-wide analysis of the ABCB gene family in <i>Vitis vinifera</i>: its expression patterns in berries and its responses to iron and heavy metal stresses

description: All living organisms contain ATP-binding cassette (ABC) transporters that perform different biological functions. Here, we identified 19 putative VvABCB from grapevine genomic and proteomic databases. Bioinformatics analyses revealed the phylogenetic relationship, conserved motifs, localisation, and structure of ABCB genes and the regulatory elements in their promoter. Twenty conserved motifs were found among the VvABCB subfamily and their properties were similar to those of ABC transporters. We showed that the <i>VvABCB</i> gene promoters contain many elements related to the light response motif in addition to gibberellin-responsive elements, auxin-responsive elements, and cis-acting element involved in abiotic stresses. The gene expression levels were also analysed at different developmental stages of berries. The transcripts levels of <i>VvABCB</i> genes differed at the various developmental stages of berries, suggesting that they are involved in growth and development. The expression profiles of <i>VvABCB</i> genes obtained via qRT-PCR were used to assess genetic responses to iron and heavy metal stresses. Iron, copper, mercury, and boron induced regulatory responses in <i>VvABCB</i> genes, which likely play a role in coping with iron and heavy metal stresses in plants. This study establishes a base for future functional research on this class of ABC transporters in grapevine.
DOI: 10.6084/m9.figshare.22227171
title: CPPU and salicylic acid application improved fruit retention, yield, and fruit quality of mango cv. Dusehri

description: The present investigation was aimed at assessing the efficacy of N1-(2-chloro-4-pyridyl)-N3-phenylurea (CPPU) and salicylic acid on fruit retention, yield, and quality of mango cv. Dusehri. The research was carried out at the Department of Fruit Science, Punjab Agricultural University, Ludhiana, India. The experiment was conducted simultaneously at two different locations for two cropping seasons during 2019–20 and 2020–21. Fruit retention enhancing treatments of 2,4-Dichlorophenoxyacetic acid (2,4-D) (@20 ppm), CPPU (@5, 10, and 15 ppm), and salicylic acid (@100, 200, and 300 ppm) were applied at pea stage of fruit growth. Experimental plants were observed for various reproductive, yield, and fruit quality parameters. The results indicated that foliar application of CPPU (T6-CPPU @10 ppm) significantly enhanced fruit retention during marble and harvest stages at both locations in both seasons. The novel growth hormone also improved fruit yield, fruit weight, and fruit quality in mango cv. Dusehri. Foliar applied salicylic acid recorded intermediate values for observed parameters. Therefore, foliar application of CPPU can be considered as a better alternative to 2,4-D for fruit drop management of mango.
DOI: 10.6084/m9.figshare.22309716.v1
title: Cloning and Characterisation of a novel phosphate transporter gene <i>EcPT1</i> from <i>Eichhornia crassipes</i>

description: <i>Eichhornia crassipes</i> (Mart.) Solms can absorb nitrogen and phosphorus efficiently from water. Cloning the phosphate transporter 1 from <i>E. crassipes</i> (<i>EcPHT1</i>) and studying its characteristics can help to explain the molecular mechanism of absorption and transportation of inorganic phosphate (Pi) in <i>E. crassipes</i> and develop new genetic resources for phosphate transport to aid genetic breeding of crops with increased phosphate use efficiency. In this paper, we have used RACE method to clone the <i>EcPT1</i> with 1572 bps which encoded a polypeptide of 523 amino acids and contained 11 transmembrane regions which was the typical structure of plant PHT1. The phylogenetic analysis also showed EcPT1 was closely related to other plant PHT1s. Quantitative real-time RT-PCR (qRT-PCR) showed that the <i>EcPT1</i> expression in roots was up-regulated under low phosphorus stress . Moreover the <i>EcPT1</i> expression in leaves was suppressed after <i>E. crassipes</i> was transferred to sufficient Pi from deficient Pi. Yeast functional complementation tests showed that the <i>EcPT1</i> could complement the phosphate transport function of the Pi deficient yeast PHO84 in 175 μM Pi and make it grow best in pH = 5 or 6. All these results indicated that <i>EcPT1</i> might be a phosphate transporter gene. Its expression was different in different tissues.
DOI: 10.6084/m9.figshare.22194452.v1
title: Genome-wide analysis of the ABCB gene family in <i>Vitis vinifera</i>: its expression patterns in berries and its responses to ion and heavy metal stresses

description: All living organisms contain ATP-binding cassette (ABC) transporters that perform different biological functions. Here, we identified 19 putative VvABCB from grapevine genomic and proteomic databases. Bioinformatics analyses revealed the phylogenetic relationship, conserved motifs, localisation, and structure of ABCB genes and the regulatory elements in their promoter. Twenty conserved motifs were found among the VvABCB subfamily and their properties were similar to those of ABC transporters. We showed that the <i>VvABCB</i> gene promoters contain many elements related to the light response motif in addition to gibberellin-responsive elements, auxin-responsive elements, and cis-acting element involved in abiotic stresses. The gene expression levels were also analysed at different developmental stages of berries. The transcripts levels of <i>VvABCB</i> genes differed at the various developmental stages of berries, suggesting that they are involved in growth and development. The expression profiles of <i>VvABCB</i> genes obtained via qRT-PCR were used to assess genetic responses to ion and heavy metal stresses. Iron, copper, mercury, and boron induced regulatory responses in <i>VvABCB</i> genes, which likely play a role in coping with iron and heavy metal stresses in plants. This study establishes a base for future functional research on this class of ABC transporters in grapevine.
DOI: 10.6084/m9.figshare.22194452.v2
title: Genome-wide analysis of the ABCB gene family in <i>Vitis vinifera</i>: its expression patterns in berries and its responses to iron and heavy metal stresses

description: All living organisms contain ATP-binding cassette (ABC) transporters that perform different biological functions. Here, we identified 19 putative VvABCB from grapevine genomic and proteomic databases. Bioinformatics analyses revealed the phylogenetic relationship, conserved motifs, localisation, and structure of ABCB genes and the regulatory elements in their promoter. Twenty conserved motifs were found among the VvABCB subfamily and their properties were similar to those of ABC transporters. We showed that the <i>VvABCB</i> gene promoters contain many elements related to the light response motif in addition to gibberellin-responsive elements, auxin-responsive elements, and cis-acting element involved in abiotic stresses. The gene expression levels were also analysed at different developmental stages of berries. The transcripts levels of <i>VvABCB</i> genes differed at the various developmental stages of berries, suggesting that they are involved in growth and development. The expression profiles of <i>VvABCB</i> genes obtained via qRT-PCR were used to assess genetic responses to iron and heavy metal stresses. Iron, copper, mercury, and boron induced regulatory responses in <i>VvABCB</i> genes, which likely play a role in coping with iron and heavy metal stresses in plants. This study establishes a base for future functional research on this class of ABC transporters in grapevine.
DOI: 10.6084/m9.figshare.22227171.v1
title: CPPU and salicylic acid application improved fruit retention, yield, and fruit quality of mango cv. Dusehri

description: The present investigation was aimed at assessing the efficacy of N1-(2-chloro-4-pyridyl)-N3-phenylurea (CPPU) and salicylic acid on fruit retention, yield, and quality of mango cv. Dusehri. The research was carried out at the Department of Fruit Science, Punjab Agricultural University, Ludhiana, India. The experiment was conducted simultaneously at two different locations for two cropping seasons during 2019–20 and 2020–21. Fruit retention enhancing treatments of 2,4-Dichlorophenoxyacetic acid (2,4-D) (@20 ppm), CPPU (@5, 10, and 15 ppm), and salicylic acid (@100, 200, and 300 ppm) were applied at pea stage of fruit growth. Experimental plants were observed for various reproductive, yield, and fruit quality parameters. The results indicated that foliar application of CPPU (T6-CPPU @10 ppm) significantly enhanced fruit retention during marble and harvest stages at both locations in both seasons. The novel growth hormone also improved fruit yield, fruit weight, and fruit quality in mango cv. Dusehri. Foliar applied salicylic acid recorded intermediate values for observed parameters. Therefore, foliar application of CPPU can be considered as a better alternative to 2,4-D for fruit drop management of mango.
DOI: 10.6084/m9.figshare.23918610.v1
title: Supplementary Material for: Analysis of hematological indices and splenectomy rates in 2,130 patients with Hemoglobin H diseases or β-thalassemia

description: Introduction Splenomegaly and hypersplenism are common complications of thalassemia patients due to the excessive clearance of defective red blood cells from the spleen. To date, splenectomy has been considered one of the most effective treatments for splenomegaly, reducing clinical severity among thalassemia patients. Thus, we aim to investigate the differences in splenectomy rates and hematological indices among thalassemia patients with different genotypes. Method In this study, we analyzed the clinical data of thalassemia in 2,130 patients admitted to the 923rd Hospital of the People’s Liberation Army from January 2006 to December 2020, and the statistical software SPSS 26.0 was applied to analyze the data. Result Of the 2,130 patients with thalassemia, 265 patients underwent splenectomy. It was determined that significantly more patients with hemoglobin H (HbH) disease, a form of α-thalassemia, have undergone splenectomy than β-thalassemia patients (20% vs. 7%). Further, HbH disease patients were diagnosed at a significantly older age than β-thalassemia patients. Conclusion The greater probability of HbH disease patients undergoing splenectomy is likely influenced by multiple factors, including their lower dependency on transfusion, leading to high spleen compensatory stress on the spleen and the destruction of defective erythrocytes. In contrast, β-thalassemia is clinically more severe and less tolerant of hemoglobin fluctuations. Based on these findings, clinicians are suggested to pay more attention to HbH patients as many of them are still under-transfused, which could lead to chronic hemolysis and more severe hepatosplenomegaly. These results might offer insight for improving the clinical management of patients with different types of thalassemia.
DOI: 10.57841/casdc.0001792
title: 碳纤维和氟化钙协同提高PTFE摩擦学性能研究
DOI: 10.57841/casdc.0001793
title: 0Cr18Ni9Ti-U71Mn摩擦副高速重载磨损行为的数值模拟