cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.24954945
title: A nondestructive testing dataset of rocks with different section shapes, different integralities, and different flaws

description: Structure of folders<pre>  Dataset<br>  ├── 1.shape<br>  | ├── R-S-0-0-0(circle)<br>  | └── R-C-0-0-0(square)<br>  ├── 2.crackLengthAndShape<br>  | ├── G-I-0-0-0(no crack)<br>  | ├── G-N-1-1-5(1mmx5mm)<br>  | ├── G-N-1-1-10(1mmx10mm)<br>  | ├── G-N-1-1-15(1mmx15mm)<br>  | ├── G-N-1-1-20(1mmx20mm)<br>  | ├── G-N-1-2-5(2mmx5mm)<br>  | ├── G-N-1-3-5(3mmx5mm)<br>  | ├── G-N-1-4-5(4mmx5mm)<br>  | ├── G-N-1-5-5(5mmx5mm)<br>  | ├── G-N-2-1-5(double1mmx5mm)<br>  | ├── G-N-2-1-10(double1mmx5mm)<br>  | ├── G-N-4-1-5(quadruple1mmx5mm)<br>  └── README.md<br>  <br>  directory: 14</pre>Data formatIn the collection stage, samples for each time period are annotated through manual recording. During the dataset construction phase, the data is partitioned based on the index supplied by the internal data structure within the file. The mechanical wave detection captured a singular signal pulse spanning a duration of 1638.4 microseconds. In accordance with the instrument's sampling interval of 0.2 microseconds, Python was utilized to transfer signal data in the form of a matrix with dimensions 8192×2.Dataset overviewThis dataset can be very huge (192 GB), so it is compressed in zip format.The total data number in this dataset is summarized in Table: Subdirectory Number of data (Unit: unit) Subdirectory Number of data (Unit: unit) Subdirectory Number of data (Unit: unit) R-S-0-0-0 82930 G-N-1-1-15 59227 G-N-1-5-5 58696 R-C-0-0-0 109217 G-N-1-1-20 90721 G-N-2-1-5 61088 G-I-0-0-0 112596 G-N-1-2-5 53833 G-N-2-1-10 61340 G-N-1-1-5 31814 G-N-1-3-5 57700 G-N-4-1-5 81908 G-N-1-1-10 56403 G-N-1-4-5 77939 Total 995412 <br><b>Acknowledgement</b>Readers are welcome to use this dataset for any type of research.Creator: Zhuoran Tian, Chunjiang ZouDataset correspondence: 220204912@aa.seu.edu.cn, chunjiang.zou@brunel.ac.uk
DOI: 10.6084/m9.figshare.24954945.v1
title: A nondestructive testing dataset of rocks with different section shapes, different integralities, and different flaws

description: Structure of folders<pre>  Dataset<br>  ├── 1.shape<br>  | ├── R-S-0-0-0(circle)<br>  | └── R-C-0-0-0(square)<br>  ├── 2.crackLengthAndShape<br>  | ├── G-I-0-0-0(no crack)<br>  | ├── G-N-1-1-5(1mmx5mm)<br>  | ├── G-N-1-1-10(1mmx10mm)<br>  | ├── G-N-1-1-15(1mmx15mm)<br>  | ├── G-N-1-1-20(1mmx20mm)<br>  | ├── G-N-1-2-5(2mmx5mm)<br>  | ├── G-N-1-3-5(3mmx5mm)<br>  | ├── G-N-1-4-5(4mmx5mm)<br>  | ├── G-N-1-5-5(5mmx5mm)<br>  | ├── G-N-2-1-5(double1mmx5mm)<br>  | ├── G-N-2-1-10(double1mmx5mm)<br>  | ├── G-N-4-1-5(quadruple1mmx5mm)<br>  └── README.md<br>  <br>  directory: 14</pre>Data formatIn the collection stage, samples for each time period are annotated through manual recording. During the dataset construction phase, the data is partitioned based on the index supplied by the internal data structure within the file. The mechanical wave detection captured a singular signal pulse spanning a duration of 1638.4 microseconds. In accordance with the instrument's sampling interval of 0.2 microseconds, Python was utilized to transfer signal data in the form of a matrix with dimensions 8192×2.Dataset overviewThis dataset can be very huge (207 GB), so it is compressed in zip format.The total data number in this dataset is summarized in Table: Subdirectory Number of data (Unit: unit) Subdirectory Number of data (Unit: unit) Subdirectory Number of data (Unit: unit) R-S-0-0-0 82930 G-N-1-1-15 59227 G-N-1-5-5 58696 R-C-0-0-0 109217 G-N-1-1-20 90721 G-N-2-1-5 61088 G-I-0-0-0 112596 G-N-1-2-5 53833 G-N-2-1-10 61340 G-N-1-1-5 31814 G-N-1-3-5 57700 G-N-4-1-5 81908 G-N-1-1-10 56403 G-N-1-4-5 77939 Total 995412 <b>Acknowledgment</b>Readers are welcome to use this dataset for any type of research.Creator: Zhuoran Tian, Chunjiang ZouDataset correspondence: 220204912@aa.seu.edu.cn, chunjiang.zou@brunel.ac.uk
DOI: 10.6084/m9.figshare.24954945.v2
title: A nondestructive testing dataset of rocks with different section shapes, different integralities, and different flaws

description: Structure of folders<pre>  Dataset<br>  ├── 1.shape<br>  | ├── R-S-0-0-0(circle)<br>  | └── R-C-0-0-0(square)<br>  ├── 2.crackLengthAndShape<br>  | ├── G-I-0-0-0(no crack)<br>  | ├── G-N-1-1-5(1mmx5mm)<br>  | ├── G-N-1-1-10(1mmx10mm)<br>  | ├── G-N-1-1-15(1mmx15mm)<br>  | ├── G-N-1-1-20(1mmx20mm)<br>  | ├── G-N-1-2-5(2mmx5mm)<br>  | ├── G-N-1-3-5(3mmx5mm)<br>  | ├── G-N-1-4-5(4mmx5mm)<br>  | ├── G-N-1-5-5(5mmx5mm)<br>  | ├── G-N-2-1-5(double1mmx5mm)<br>  | ├── G-N-2-1-10(double1mmx5mm)<br>  | ├── G-N-4-1-5(quadruple1mmx5mm)<br>  └── README.md<br>  <br>  directory: 14</pre>Data formatIn the collection stage, samples for each time period are annotated through manual recording. During the dataset construction phase, the data is partitioned based on the index supplied by the internal data structure within the file. The mechanical wave detection captured a singular signal pulse spanning a duration of 1638.4 microseconds. In accordance with the instrument's sampling interval of 0.2 microseconds, Python was utilized to transfer signal data in the form of a matrix with dimensions 8192×2.Dataset overviewThis dataset can be very huge (192 GB), so it is compressed in zip format.The total data number in this dataset is summarized in Table: Subdirectory Number of data (Unit: unit) Subdirectory Number of data (Unit: unit) Subdirectory Number of data (Unit: unit) R-S-0-0-0 82930 G-N-1-1-15 59227 G-N-1-5-5 58696 R-C-0-0-0 109217 G-N-1-1-20 90721 G-N-2-1-5 61088 G-I-0-0-0 112596 G-N-1-2-5 53833 G-N-2-1-10 61340 G-N-1-1-5 31814 G-N-1-3-5 57700 G-N-4-1-5 81908 G-N-1-1-10 56403 G-N-1-4-5 77939 Total 995412 <br><b>Acknowledgement</b>Readers are welcome to use this dataset for any type of research.Creator: Zhuoran Tian, Chunjiang ZouDataset correspondence: 220204912@aa.seu.edu.cn, chunjiang.zou@brunel.ac.uk
DOI: 10.6084/m9.figshare.25266970
title: Intracellular Zn<sup>2+</sup> Promotes Extracellular Matrix Remodeling in Dexamethasone-Treated Trabecular Meshwork

description: Given the widespread application of glucocorticoids in ophthalmology, the associated elevation of intraocular pressure (IOP) has long been a vexing concern for clinicians, yet the underlying mechanisms remain inconclusive. Much of the discussion focuses on the extracellular matrix (ECM) of trabecular meshwork (TM). It's widely agreed that glucocorticoids impact the expression of matrix metalloproteinases (MMPs), leading to ECM deposition. Since Zn2+ is vital for MMPs, we explored its role in ECM alterations induced by dexamethasone (DEX). Our study revealed that in human TM cells treated with DEX, the level of intracellular Zn2+ significantly decreased and accompanied by impaired extracellular Zn2+ uptake. This correlated with changes in several Zrt-, Irt-related proteins (ZIP) and metallothionein. ZIP8 knockdown impaired extracellular Zn2+ uptake, but Zn2+ chelation didn't affect ZIP8 expression. Resembling DEX's effects, chelating Zn2+ decreased MMP2 expression, increased the deposition of ECM proteins, and induced structural disarray of ECM. Conversely, supplementation of exogenous Zn2+ to DEX-treated cells ameliorated these outcomes. Inspiringly, dietary zinc supplementation in mice significantly reduced DEX-induced IOP elevation and collagen content in TM, thereby rescuing the visual function of the mice. These findings underscore zinc's pivotal role in ECM regulation, providing a novel perspective on the pathogenesis of glaucoma.
DOI: 10.6084/m9.figshare.25266970.v1
title: Intracellular Zn<sup>2+</sup> Promotes Extracellular Matrix Remodeling in Dexamethasone-Treated Trabecular Meshwork

description: Given the widespread application of glucocorticoids in ophthalmology, the associated elevation of intraocular pressure (IOP) has long been a vexing concern for clinicians, yet the underlying mechanisms remain inconclusive. Much of the discussion focuses on the extracellular matrix (ECM) of trabecular meshwork (TM). It's widely agreed that glucocorticoids impact the expression of matrix metalloproteinases (MMPs), leading to ECM deposition. Since Zn2+ is vital for MMPs, we explored its role in ECM alterations induced by dexamethasone (DEX). Our study revealed that in human TM cells treated with DEX, the level of intracellular Zn2+ significantly decreased and accompanied by impaired extracellular Zn2+ uptake. This correlated with changes in several Zrt-, Irt-related proteins (ZIP) and metallothionein. ZIP8 knockdown impaired extracellular Zn2+ uptake, but Zn2+ chelation didn't affect ZIP8 expression. Resembling DEX's effects, chelating Zn2+ decreased MMP2 expression, increased the deposition of ECM proteins, and induced structural disarray of ECM. Conversely, supplementation of exogenous Zn2+ to DEX-treated cells ameliorated these outcomes. Inspiringly, dietary zinc supplementation in mice significantly reduced DEX-induced IOP elevation and collagen content in TM, thereby rescuing the visual function of the mice. These findings underscore zinc's pivotal role in ECM regulation, providing a novel perspective on the pathogenesis of glaucoma.
DOI: 10.6084/m9.figshare.25266994
title: Supplemental Materials: Intracellular Zn<sup>2+</sup> Promotes Extracellular Matrix Remodeling in Dexamethasone-Treated Trabecular Meshwork

description: Supplemental Materials: Intracellular Zn<sup>2+</sup> Promotes Extracellular Matrix Remodeling in Dexamethasone-Treated Trabecular Meshwork
DOI: 10.6084/m9.figshare.25266994.v1
title: Supplemental Materials: Intracellular Zn<sup>2+</sup> Promotes Extracellular Matrix Remodeling in Dexamethasone-Treated Trabecular Meshwork

description: Supplemental Materials: Intracellular Zn<sup>2+</sup> Promotes Extracellular Matrix Remodeling in Dexamethasone-Treated Trabecular Meshwork
DOI: 10.6084/m9.figshare.25272505
title: Qualitative Study_ACS_Yogyakarta_Indonesia_2019-2022

description: Indonesia, located in Southeast Asia, is the world's fourth most populated country. ACS is regarded as a leading cause of death and disability in Indonesia. Prior to the COVID-19 epidemic, unmet timely care needs among ACS patients in Indonesia were a major problem. From 3 January 2020 to 16 August 2023, about 6,813,000 confirmed cases of COVID-19 were reported in Indonesia, with 161,916 deaths. It is critical to understand patients' treatment seeking behavior as well as the hurdles that may contribute to delayed presentation of ACS patients to health institutions during the pandemic. This qualitative study, therefore, aimed to explore patients’ treatment seeking behavior, barriers in seeking medical treatment, and treatment experiences of patients with ACS during the COVID-19 pandemic. The findings from this study could serve as an essential lesson for healthcare workers and policymakers looking to establish appropriate and practical measures to encourage individuals with ACS to seek medical care in a timely and effective manner during the next health crisis.
DOI: 10.6084/m9.figshare.25297993
title: Asymmetric synthesis, characterization of chiral <i>trans</i> and <i>cis</i>-3-chloro/oxo/thio-4-styryl-<i>β</i>-lactams using (<i>R</i>)-(+)-1-phenylethylamine and their efficient column chromatographic separation

description: Diverse chiral <i>trans</i> and <i>cis</i>-3-chloro/oxo/thio-4-styryl-<i>β</i>-lactams were efficiently synthesized using chiral 3′-phenylallylidene-[(<i>R</i>)-1′-phenylethyl] amine and substituted ethanoic acids. Moore ketenes derived from chloro/phenythio/benzylthio ethanoic acids (Cl/PhS/BzS) affords both chiral <i>trans</i>- and <i>cis β</i>-lactams, with a preference for <i>trans</i>-stereochemistry. However, Bose-Evans ketenes obtained from 2-methoxy/phenoxyethanoic acids (MeO/PhO), led to the exclusive formation of <i>cis</i>-diastereomers only. Further, individual diastereomers of <i>trans</i>- and <i>cis-β</i>-lactams were separated <i>via</i> efficient column chromatography. The relative <i>cis</i> and <i>trans</i> configuration of the C-3 and C-4 protons in chiral <i>β</i>-lactams was established using coupling constant value ranging from <i>J</i> = 1.4 to 2.1 Hz (in case of <i>trans</i>) and <i>J</i> = 4.3 to 5.2 Hz (in case of <i>cis</i>) respectively. Structural confirmation of <i>β</i>-lactams was done using FT-IR, NMR (<sup>1</sup>H,<sup>13</sup>C,<sup>1</sup>H-<sup>1</sup>H COSY and <sup>1</sup>H-<sup>13</sup>C HSQC), elemental analysis, ESI-MS and X-ray crystallography.
DOI: 10.6084/m9.figshare.25297993.v1
title: Asymmetric synthesis, characterization of chiral <i>trans</i> and <i>cis</i>-3-chloro/oxo/thio-4-styryl-<i>β</i>-lactams using (<i>R</i>)-(+)-1-phenylethylamine and their efficient column chromatographic separation

description: Diverse chiral <i>trans</i> and <i>cis</i>-3-chloro/oxo/thio-4-styryl-<i>β</i>-lactams were efficiently synthesized using chiral 3′-phenylallylidene-[(<i>R</i>)-1′-phenylethyl] amine and substituted ethanoic acids. Moore ketenes derived from chloro/phenythio/benzylthio ethanoic acids (Cl/PhS/BzS) affords both chiral <i>trans</i>- and <i>cis β</i>-lactams, with a preference for <i>trans</i>-stereochemistry. However, Bose-Evans ketenes obtained from 2-methoxy/phenoxyethanoic acids (MeO/PhO), led to the exclusive formation of <i>cis</i>-diastereomers only. Further, individual diastereomers of <i>trans</i>- and <i>cis-β</i>-lactams were separated <i>via</i> efficient column chromatography. The relative <i>cis</i> and <i>trans</i> configuration of the C-3 and C-4 protons in chiral <i>β</i>-lactams was established using coupling constant value ranging from <i>J</i> = 1.4 to 2.1 Hz (in case of <i>trans</i>) and <i>J</i> = 4.3 to 5.2 Hz (in case of <i>cis</i>) respectively. Structural confirmation of <i>β</i>-lactams was done using FT-IR, NMR (<sup>1</sup>H,<sup>13</sup>C,<sup>1</sup>H-<sup>1</sup>H COSY and <sup>1</sup>H-<sup>13</sup>C HSQC), elemental analysis, ESI-MS and X-ray crystallography.
DOI: 10.6084/m9.figshare.25302031.v1
title: Amplified positive environmental and energy effects under China' carbon neutrality

description: We analyze the amplified air quality, human health, and renewable energy self-reinforcing synergies of China’s carbon neutral target. Our results highlight that global developing and polluting countries’ quest for carbon neutrality can produce important positive feedbacks between aerosols mitigation, air quality improvement, and enhanced renewable energy, which can be amplified via weakened aerosol-meteorology interactions and better atmospheric dispersion.
DOI: 10.6084/m9.figshare.25302031.v2
title: Amplified positive environmental and energy effects under China' carbon neutrality

description: We analyze the amplified air quality, human health, and renewable energy self-reinforcing synergies of China’s carbon neutral target. Our results highlight that global developing and polluting countries’ quest for carbon neutrality can produce important positive feedbacks between aerosols mitigation, air quality improvement, and enhanced renewable energy, which can be amplified via weakened aerosol-meteorology interactions and better atmospheric dispersion.
DOI: 10.6084/m9.figshare.25302031.v3
title: Amplified positive environmental and energy effects under China' carbon neutrality

description: We analyze the amplified air quality, human health, and renewable energy self-reinforcing synergies of China’s carbon neutral target. Our results highlight that global developing and polluting countries’ quest for carbon neutrality can produce important positive feedbacks between aerosols mitigation, air quality improvement, and enhanced renewable energy, which can be amplified via weakened aerosol-meteorology interactions and better atmospheric dispersion.
DOI: 10.6084/m9.figshare.25302031.v4
title: Amplified positive environmental and energy effects under China' carbon neutrality

description: We analyze the amplified air quality, human health, and renewable energy self-reinforcing synergies of China’s carbon neutral target. Our results highlight that global developing and polluting countries’ quest for carbon neutrality can produce important positive feedbacks between aerosols mitigation, air quality improvement, and enhanced renewable energy, which can be amplified via weakened aerosol-meteorology interactions and better atmospheric dispersion.
DOI: 10.6084/m9.figshare.25302031.v5
title: Amplified positive environmental and energy effects under China' carbon neutrality

description: We analyze the amplified air quality, human health, and renewable energy self-reinforcing synergies of China’s carbon neutral target. Our results highlight that global developing and polluting countries’ quest for carbon neutrality can produce important positive feedbacks between aerosols mitigation, air quality improvement, and enhanced renewable energy, which can be amplified via weakened aerosol-meteorology interactions and better atmospheric dispersion.
DOI: 10.6084/m9.figshare.25335541
title: Data and metadata for Malawauw et al., <i>'Parasitism in reef fish communities: evaluating the roles </i><i>of host traits, habitat use, and phylogeny on infection </i><i>by Scaphanocephalus (Trematoda)'</i>

description: These files contain the data and metadata from Malawauw et al., <i>'Parasitism in reef fish communities: evaluating the roles </i><i>of host traits, habitat use, and phylogeny on infection </i><i>by Scaphanocephalus (Trematoda)'</i>
DOI: 10.6084/m9.figshare.25335541.v1
title: Data and metadata for Malawauw et al., <i>'Parasitism in reef fish communities: evaluating the roles </i><i>of host traits, habitat use, and phylogeny on infection </i><i>by Scaphanocephalus (Trematoda)'</i>

description: These files contain the data and metadata from Malawauw et al., <i>'Parasitism in reef fish communities: evaluating the roles </i><i>of host traits, habitat use, and phylogeny on infection </i><i>by Scaphanocephalus (Trematoda)'</i>
DOI: 10.5281/zenodo.10868775
title: Data analysis and benchmark results for: "hictk: blazing fast toolkit to work with .hic and .cool files"

description: README

Data found in this dataset was generated as part of the following publication: "hictk: blazing fast toolkit to work with .hic and .cool files" (preprint available soon).The data analysis pipeline used to generate the data is hosted on GitHub at github.com/paulsengroup/2023-hictk-paper and archived on Zenodo doi.org/10.5281/zenodo.10868277.

Refer to the README found in the .zip file for more information on how the data is organized.

Contact information

Inquiries regarding this dataset should be addressed to the corresponding author for "hictk: blazing fast toolkit to work with .hic and .cool files" (Jonas Paulsen).
DOI: 10.5281/zenodo.8331155
title: Data analysis and benchmark results for: "hictk: blazing fast toolkit to work with .hic and .cool files"

description: README

Data found in this dataset was generated as part of the following publication: "hictk: blazing fast toolkit to work with .hic and .cool files" (preprint available soon).The data analysis pipeline used to generate the data is hosted on GitHub at github.com/paulsengroup/2023-hictk-paper and archived on Zenodo doi.org/10.5281/zenodo.10868277.

Refer to the README found in the .zip file for more information on how the data is organized.

Contact information

Inquiries regarding this dataset should be addressed to the corresponding author for "hictk: blazing fast toolkit to work with .hic and .cool files" (Jonas Paulsen).
DOI: 10.5281/zenodo.8331156
title: Data analysis and benchmark results for: "hictk: blazing fast toolkit to work with .hic and .cool files"

description: <strong>README</strong> Data found in this dataset was generated as part of the following publication: "hictk: blazing fast toolkit to work with .hic and .cool files" (preprint available soon).<br> <br> The data analysis pipeline used to generate the data is hosted on GitHub at github.com/paulsengroup/2023-hictk-paper and archived on Zenodo doi.org/10.5281/zenodo.8331042. Refer to the README found in the .zip file for more information on how the data is organized. <strong>Contact information</strong> Inquiries regarding this dataset should be addressed to the corresponding author for "hictk: blazing fast toolkit to work with .hic and .cool files" (Jonas Paulsen).
DOI: 10.5281/zenodo.10875997
title: Block-oriented description of a fictional CHP generation plant for unit commitment testing

description: Block-oriented description of a fictional combined heat&power generation plant for unit commitment testing.

Example input data is available at: https://doi.org/10.5281/zenodo.10875471
DOI: 10.5281/zenodo.10875998
title: Block-oriented description of a fictional CHP generation plant for unit commitment testing

description: Block-oriented description of a fictional combined heat&power generation plant for unit commitment testing.

Example input data is available at: https://doi.org/10.5281/zenodo.10875471
DOI: 10.6084/m9.figshare.25451689.v12
title: 1_perception&motor_EEGdata

description: EEG data for experiment 1.Each folder contains:a) Raw EEG files for one subject (subX), named as "subX.cnt" and "subX.evt" generated by ANT eego device;b) "subX.seg" files contains the segment time if the EEG recording was paused during experiment (NOT for all subjects);c) a log file (.txt) that records all information during preprocessing;d) pure EEG datasets (.set file generated by eeglab) for each of four conditions.
DOI: 10.6084/m9.figshare.25379827
title: Data from "Ant queens cannibalise infected brood to contain disease spread and recycle nutrients"

description: Data arising from "Ant queens cannibalise infected brood to contain disease spread and recycle nutrients". Experiment were performed finding that solitarily founding ant queens cannibalise all sick larvae in their nests before they become contagious, showing clearly that filial cannibalism both (i) contains an otherwise lethal infection without any long-term consequences on queen survival and (ii) enables the reinvestment of recouped energy into additional egg production. See published manuscript for full details.Data sets<i>larval_cannibalism</i> – number of larvae cannibalised by queens; description of data included in file.<i>larval_cannibalism_rates</i> – number of larvae cannibalised by queens over time; description of data included in file.<i>longterm_survival</i><i> _and_final_colony_size</i> – longterm survival and colony sizes of queens post-cannibalism; description of data included in file.<i>queen_survival</i> – survival of queens presented with infectious larvae; description of data included in file.<i>eggs</i> - number of eggs laid by cannibal and non-cannibal queens;description of data included in file.R codeAll R analysis code and output provided for each analysis performed (on above data); every file is fully annotated.
DOI: 10.6084/m9.figshare.25382560
title: ML.raxml.treefile.Decker.et.al..support

description: <b>Boring systematics: a genome skimmed phylogeny of ctenostome bryozoans and their endolithic family Penetrantiidae with the description of one new species</b>
DOI: 10.6084/m9.figshare.25382560.v1
title: ML.raxml.treefile.Decker.et.al..support

description: <b>Boring systematics: a genome skimmed phylogeny of ctenostome bryozoans and their endolithic family Penetrantiidae with the description of one new species</b>
DOI: 10.6084/m9.figshare.25388377
title: The raw data of the SKIP14.A2-OE/CK transgenic hairy roots' ubiquitinome in rapeseeds

description: To system-wide identify the degradation substrates of SKIP14.A2, 35S::<i>SKIP14.A</i>2 transgenic ZS11 hairy roots were constructed, and the independently expressed mGFP (with the promoter of 2×35S) was used as a screening marker for positive transgenic materials. Hairy roots with GFP signals produced by the same cotyledon are used as "OE" materials, while hairy roots without GFP signals are used as "CK" materials. RT-PCR assay with these two groups showed that the expression of target gene in OE-1/2/3 sample was increased by 29.309, 73.164 and 28.573 times compared with CK1/2/3, respectively. Subsequently, OE and CK groups were carried out for ubiquitinome (4D-fastDIA) analysis.