cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.21835300
title: 4-Carvomenthenol, a monoterpene of essential oils, and its underlying effects on anti-inflammatory activity and immediate hypersensitivity reaction

description: Abstract The monoterpene 4-carvomenthenol (Carvo) is found in essential oils of plant. Here, we evaluate the Carvo oral pretreatment in acute inflammatory experimental models and in silico molecular docking. Mice pretreated with Carvo were challenged and submitted to the protocols: paw edema, peritonitis, scratching behavior and anaphylactic shock reaction. Besides, we used histamine H1 receptor, cyclooxygenases (COX-1 and COX-2) and phospholipase A2, as targets for molecular docking analysis. Carvo inhibited the carrageenan-induced paw edema and decreased the peritoneal influx of polymorphonuclear cells on carrageenan-challenged mice without interfering with the mononuclear cell influx. Moreover, Carvo diminished the histamine, PGE2 and compound 48/80 induced paw edematogenic effect. The monoterpene also diminished the mice scratching behavior and, surprisingly, avoided the animal death caused by compound 48/80 in 30 min. Through the docking analysis, Carvo showed favorable binding energy to the histamine H1 receptor. This study demonstrates that Carvo attenuated the allergic inflammatory process, decreasing edema, cell migration, activation of mast cells and the histamine release, probably due to interaction of Carvo with the histamine H1 receptor, ameliorating the itching and the anaphylactic shock reaction. Therefore, the results of this study indicate that Carvo has anti-inflammatory properties by reducing the histamine effects.
DOI: 10.6084/m9.figshare.21835300.v1
title: 4-Carvomenthenol, a monoterpene of essential oils, and its underlying effects on anti-inflammatory activity and immediate hypersensitivity reaction

description: Abstract The monoterpene 4-carvomenthenol (Carvo) is found in essential oils of plant. Here, we evaluate the Carvo oral pretreatment in acute inflammatory experimental models and in silico molecular docking. Mice pretreated with Carvo were challenged and submitted to the protocols: paw edema, peritonitis, scratching behavior and anaphylactic shock reaction. Besides, we used histamine H1 receptor, cyclooxygenases (COX-1 and COX-2) and phospholipase A2, as targets for molecular docking analysis. Carvo inhibited the carrageenan-induced paw edema and decreased the peritoneal influx of polymorphonuclear cells on carrageenan-challenged mice without interfering with the mononuclear cell influx. Moreover, Carvo diminished the histamine, PGE2 and compound 48/80 induced paw edematogenic effect. The monoterpene also diminished the mice scratching behavior and, surprisingly, avoided the animal death caused by compound 48/80 in 30 min. Through the docking analysis, Carvo showed favorable binding energy to the histamine H1 receptor. This study demonstrates that Carvo attenuated the allergic inflammatory process, decreasing edema, cell migration, activation of mast cells and the histamine release, probably due to interaction of Carvo with the histamine H1 receptor, ameliorating the itching and the anaphylactic shock reaction. Therefore, the results of this study indicate that Carvo has anti-inflammatory properties by reducing the histamine effects.
DOI: 10.6084/m9.figshare.21835303
title: Perception of discrimination against immigrants compared to Chilean-born and its relationship with access to services and health outcomes

description: ABSTRACT OBJECTIVES Compare self-perceived discrimination between immigrants and locals in Chile and analyze the relationship between immigration and perceived discrimination and immigration, discrimination and health outcomes, adjusting for sociodemographic characteristics and social capital. METHODS Cross-sectional study, using population-based survey (CASEN2017). We selected 2,409 immigrants (representative of N = 291,270) and 67,857 locals (representative of N = 5,438,036) over 18 years of age surveyed. We estimated logistic regression models, considering the complex sample, with discrimination, self-rated health, medical treatment, healthcare system membership, complementary health insurance, medical consultation and problems when consulting as dependent variables, immigration and discrimination as main exposure variables, and social capital and sociodemographic variables as covariates of the models. RESULTS Immigrants were more likely to perceive discrimination in general compared to locals (OR = 2.31; 95%CI: 1.9-2.9). However, this does not occur for all specific reasons for discrimination; skin color and physical appearance were the most frequent causes of discrimination in immigrants. The interaction between immigration and discrimination was significantly related to worse self-rated health outcomes and treatment for pathologies, disfavoring discrimination against immigrants. In both locals and immigrants, discrimination was not associated with health care access outcomes, except for problems during consultation in locals (OR = 1.61; 95%CI 1.4-1.8). CONCLUSIONS In Chile, experiences of discrimination are intertwined with other forms of rejection and social exclusion, so it is urgent to raise awareness among the population to prevent these discriminatory practices, especially in health care and daily use places. It is essential to address discrimination in order to have an impact on intermediate variables and health outcomes. The extension of the results to the entire immigrant population could be very useful to deepen the problem and improve the estimates made.
DOI: 10.6084/m9.figshare.21835303.v1
title: Perception of discrimination against immigrants compared to Chilean-born and its relationship with access to services and health outcomes

description: ABSTRACT OBJECTIVES Compare self-perceived discrimination between immigrants and locals in Chile and analyze the relationship between immigration and perceived discrimination and immigration, discrimination and health outcomes, adjusting for sociodemographic characteristics and social capital. METHODS Cross-sectional study, using population-based survey (CASEN2017). We selected 2,409 immigrants (representative of N = 291,270) and 67,857 locals (representative of N = 5,438,036) over 18 years of age surveyed. We estimated logistic regression models, considering the complex sample, with discrimination, self-rated health, medical treatment, healthcare system membership, complementary health insurance, medical consultation and problems when consulting as dependent variables, immigration and discrimination as main exposure variables, and social capital and sociodemographic variables as covariates of the models. RESULTS Immigrants were more likely to perceive discrimination in general compared to locals (OR = 2.31; 95%CI: 1.9-2.9). However, this does not occur for all specific reasons for discrimination; skin color and physical appearance were the most frequent causes of discrimination in immigrants. The interaction between immigration and discrimination was significantly related to worse self-rated health outcomes and treatment for pathologies, disfavoring discrimination against immigrants. In both locals and immigrants, discrimination was not associated with health care access outcomes, except for problems during consultation in locals (OR = 1.61; 95%CI 1.4-1.8). CONCLUSIONS In Chile, experiences of discrimination are intertwined with other forms of rejection and social exclusion, so it is urgent to raise awareness among the population to prevent these discriminatory practices, especially in health care and daily use places. It is essential to address discrimination in order to have an impact on intermediate variables and health outcomes. The extension of the results to the entire immigrant population could be very useful to deepen the problem and improve the estimates made.
DOI: 10.6084/m9.figshare.21835306
title: A scientometric study of the molecular data on Brazilian red algae

description: ABSTRACT The growth in the number of molecular sequences produced in recent years has provided valuable contributions to the knowledge diversity of red algae (Rhodophyta) in Brazil. However, many works indicate that there is still much to be studied. Here, we highlight the importance of compiling all these data to evidence possible taxonomic and geographic knowledge gaps in red algae through molecular data. So, this study presents a scientometric analysis of the molecular studies carried out on red algae in Brazil, based on the analysis of DNA sequences available in the public database GenBank. Our results demonstrated an increase in published papers from 1994 to 2020, corresponding to 165 studies analyzed. A huge disparity in the production of knowledge was observed, with the southeastern region concentrating the researchers responsible for most of the published studies, with emphasis on those in the University of São Paulo (USP). Bahia and São Paulo states stand out with the highest observed taxonomic richness, respectively. We also could identify the taxonomic groups with more molecular data generated, the sequence number deposited per institution since 1994, the main markers used, the regions that require a greater collection effort, and where the researchers who study red algae in the country are.
DOI: 10.6084/m9.figshare.21835306.v1
title: A scientometric study of the molecular data on Brazilian red algae

description: ABSTRACT The growth in the number of molecular sequences produced in recent years has provided valuable contributions to the knowledge diversity of red algae (Rhodophyta) in Brazil. However, many works indicate that there is still much to be studied. Here, we highlight the importance of compiling all these data to evidence possible taxonomic and geographic knowledge gaps in red algae through molecular data. So, this study presents a scientometric analysis of the molecular studies carried out on red algae in Brazil, based on the analysis of DNA sequences available in the public database GenBank. Our results demonstrated an increase in published papers from 1994 to 2020, corresponding to 165 studies analyzed. A huge disparity in the production of knowledge was observed, with the southeastern region concentrating the researchers responsible for most of the published studies, with emphasis on those in the University of São Paulo (USP). Bahia and São Paulo states stand out with the highest observed taxonomic richness, respectively. We also could identify the taxonomic groups with more molecular data generated, the sequence number deposited per institution since 1994, the main markers used, the regions that require a greater collection effort, and where the researchers who study red algae in the country are.
DOI: 10.6084/m9.figshare.9870974.v1
title: Diseases neglected by the media and strategies for visibility from the viewpoint of key actors

description: Abstract Although health is a recurrent topic in newspapers, some diseases are visibly excluded from this coverage, originating diseases neglected by the media. The goal of this study was to identify – based on the opinion of journalists, press officers, health managers, and government health advisors – these diseases along with strategies for dealing with media neglect. The qualitative study was based on 19 semi-structured interviews with key actors. Data was submited to thematic content analysis using Maxqda software. The neglected diseases include infectious and parasitic diseases, rare diseases, periodontal diseases, cancer, and work-related illnesses.
DOI: 10.6084/m9.figshare.9870974
title: Diseases neglected by the media and strategies for visibility from the viewpoint of key actors

description: Abstract Although health is a recurrent topic in newspapers, some diseases are visibly excluded from this coverage, originating diseases neglected by the media. The goal of this study was to identify – based on the opinion of journalists, press officers, health managers, and government health advisors – these diseases along with strategies for dealing with media neglect. The qualitative study was based on 19 semi-structured interviews with key actors. Data was submited to thematic content analysis using Maxqda software. The neglected diseases include infectious and parasitic diseases, rare diseases, periodontal diseases, cancer, and work-related illnesses.
DOI: 10.6084/m9.figshare.9871370
title: How does the image of the scientist appear in short animation films?

description: Abstract This is a study on the way science and scientists are represented in short films on science and technology featured in Anima Mundi Festival (1993-2013), considering symbolic elements that contribute to the image of science. Amongst 405 films on science and technology, 102 were selected for analysis. Brazilian productions predominated (91), as did films featuring genetics, biotechnology, and astronomy. The narratives mostly address technology development, ethical considerations, and explanations of scientific processes. Scientists appear in 80% of the films – mostly white men, wearing a white coat or uniform, in secret laboratories. Scientists’ presence in public spaces – stages, the media, industry – indicates a call for their greater visibility in society.
DOI: 10.6084/m9.figshare.21835308
title: Development of processed low-sodium Maasdam cheese

description: ABSTRACT The article assesses the effect of different potassium emulsifying salts concentrations on physicochemical, colorimetric, and texture characteristics of processed cheese manufactured using Maasdam. Except for pH, physicochemical parameters remained unchanged, but the gradual substitution of sodium emulsifying salts with potassium-based salts influenced color and texture. Treatments with at least 50% potassium salts showed a reduction of at least 30% of sodium. The sodium decrease allows the product's classification as processed cheese with low-sodium content (&lt;140mg per 56.7g serving). The data obtained present substantial information that can help the dairy industries develop newly reduced-sodium products.
DOI: 10.6084/m9.figshare.21835309
title: Cartesian three-dimensional method to quantify displacements between cone beam computed tomography models

description: ABSTRACT Introduction: Research in Orthodontics and Oral Surgery has been relying on three-dimensional (3D) models to evaluate treatment results with displacement color map techniques, even though it has important limitations. Objectives: This study proposed a method of tracking translational movements of 3D objects to evaluate displacements in surfaces with no shape modification. Methods: Cone Beam Computed Tomography (CBCT) data of ten patients were imported to the Dolphin software. A hypothetical virtual surgical plan (randomly defined) was developed in the software and afterwards verified using the proposed method. All the procedures were carried out by two evaluators, in two different time-points, with a 15-day interval. ITK-Snap software was used to generate high quality STL models. Centroid points were automatically generated and their coordinates were compared to confirm if they represented the known displacements simulated. The paired t-test and the Bland-Altman plots were used, as well as the intraclass correlation coefficient. Results: Interexaminers and intra-examiner tests showed excellent reliability of the method, with mean displacement measurement error values under 0.1mm. The paired t-test did not show any statistically significant differences. Conclusion: The method showed excellent reliability to track the simulated translational displacements of bone segments.
DOI: 10.6084/m9.figshare.21835309.v1
title: Cartesian three-dimensional method to quantify displacements between cone beam computed tomography models

description: ABSTRACT Introduction: Research in Orthodontics and Oral Surgery has been relying on three-dimensional (3D) models to evaluate treatment results with displacement color map techniques, even though it has important limitations. Objectives: This study proposed a method of tracking translational movements of 3D objects to evaluate displacements in surfaces with no shape modification. Methods: Cone Beam Computed Tomography (CBCT) data of ten patients were imported to the Dolphin software. A hypothetical virtual surgical plan (randomly defined) was developed in the software and afterwards verified using the proposed method. All the procedures were carried out by two evaluators, in two different time-points, with a 15-day interval. ITK-Snap software was used to generate high quality STL models. Centroid points were automatically generated and their coordinates were compared to confirm if they represented the known displacements simulated. The paired t-test and the Bland-Altman plots were used, as well as the intraclass correlation coefficient. Results: Interexaminers and intra-examiner tests showed excellent reliability of the method, with mean displacement measurement error values under 0.1mm. The paired t-test did not show any statistically significant differences. Conclusion: The method showed excellent reliability to track the simulated translational displacements of bone segments.
DOI: 10.6084/m9.figshare.21755546
title: The genesis of neoliberalism in Brazil: an analysis of SEST adjustments

description: Abstract This article discusses the beginning of neoliberalism in Brazil during the 1980s, considering the politics introduced by the Secretariat of Control of the Public Companies (SEST) into state companies. SEST’s politics promoted neoliberalism in Brazil even before the proposals made by the IMF in 1983 and came before the Washington Consensus proposals that were implemented by the government during the 1990s, which is understood as the beginning of neoliberalism in Brazil.
DOI: 10.6084/m9.figshare.21755546.v1
title: The genesis of neoliberalism in Brazil: an analysis of SEST adjustments

description: Abstract This article discusses the beginning of neoliberalism in Brazil during the 1980s, considering the politics introduced by the Secretariat of Control of the Public Companies (SEST) into state companies. SEST’s politics promoted neoliberalism in Brazil even before the proposals made by the IMF in 1983 and came before the Washington Consensus proposals that were implemented by the government during the 1990s, which is understood as the beginning of neoliberalism in Brazil.
DOI: 10.6084/m9.figshare.21755623.v1
title: Development opportunities: economic complexity as a driver for São Paulo

description: Abstract The study analyzes the growth and development opportunities for cities in the Brazilian state of São Paulo, considering economic complexity. Our hypothesis is that the structural heterogeneity in Brazil, and in São Paulo, creates regional inequality. Therefore, cities have different development trajectories depending on their current economic capacities and productive structures. The level of economic complexity is the measurement of an economy’s ability to produce goods with a higher (or lower) level of embedded knowledge. Applying this theory to cities in the state of São Paulo indicates substantially unequal levels of complexity in the state territory, with the best indicators centered around cities such as São Paulo and Campinas. A correlation was found between the municipalities’ current level of complexity, their levels of production, and complexity outlook. Thus, based on the opportunities presented for each municipality and their engagement in this transformation process, cities will develop at different speeds and inequalities will emerge.
DOI: 10.6084/m9.figshare.21755623
title: Development opportunities: economic complexity as a driver for São Paulo

description: Abstract The study analyzes the growth and development opportunities for cities in the Brazilian state of São Paulo, considering economic complexity. Our hypothesis is that the structural heterogeneity in Brazil, and in São Paulo, creates regional inequality. Therefore, cities have different development trajectories depending on their current economic capacities and productive structures. The level of economic complexity is the measurement of an economy’s ability to produce goods with a higher (or lower) level of embedded knowledge. Applying this theory to cities in the state of São Paulo indicates substantially unequal levels of complexity in the state territory, with the best indicators centered around cities such as São Paulo and Campinas. A correlation was found between the municipalities’ current level of complexity, their levels of production, and complexity outlook. Thus, based on the opportunities presented for each municipality and their engagement in this transformation process, cities will develop at different speeds and inequalities will emerge.
DOI: 10.6084/m9.figshare.21835312
title: A retrospective report on the preoperative mandatory SARS-COV-2 infection screening in a single pediatric center. Is it time to stop testing our patients?

description: ABSTRACT The novel coronavirus SARS-COV-2 (COVID-19) pandemic dramatically changed the workflow of healthcare professionals around the world. Surgical procedures were withheld and postponed in a scenario of fear and uncertainty. Despite numerous medical institutions having swiftly and widely implemented pre-operative screening protocols, cost-effective studies remain scarce specially when comparing to other mitigation measures such as the donning of masks and social distancing measures. The objective of our study is to report the monthly positivity rates of SARS-COV-2 infection in our service and compare our data with monthly positivity rates reported by the State Health Department. Between April, 2020, to February, 2022, 7,199 patients had the RT-PCR for SARS-COV-2 collected, with 187 (2.59%) testing positive for COVID-19. Most of them (62.1%) were asymptomatic. The most common symptoms were coryza (10.7%), fever (10%), and diarrhea (8.7%). Nonetheless, there were two deaths due to COVID-19 reported in our center. Further studies are necessary to elucidate the impact of pre-operative screening for SARS-COV-2 in asymptomatic patients.
DOI: 10.6084/m9.figshare.21835312.v1
title: A retrospective report on the preoperative mandatory SARS-COV-2 infection screening in a single pediatric center. Is it time to stop testing our patients?

description: ABSTRACT The novel coronavirus SARS-COV-2 (COVID-19) pandemic dramatically changed the workflow of healthcare professionals around the world. Surgical procedures were withheld and postponed in a scenario of fear and uncertainty. Despite numerous medical institutions having swiftly and widely implemented pre-operative screening protocols, cost-effective studies remain scarce specially when comparing to other mitigation measures such as the donning of masks and social distancing measures. The objective of our study is to report the monthly positivity rates of SARS-COV-2 infection in our service and compare our data with monthly positivity rates reported by the State Health Department. Between April, 2020, to February, 2022, 7,199 patients had the RT-PCR for SARS-COV-2 collected, with 187 (2.59%) testing positive for COVID-19. Most of them (62.1%) were asymptomatic. The most common symptoms were coryza (10.7%), fever (10%), and diarrhea (8.7%). Nonetheless, there were two deaths due to COVID-19 reported in our center. Further studies are necessary to elucidate the impact of pre-operative screening for SARS-COV-2 in asymptomatic patients.