cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17632/m5f5tzdwjv
title: Pharmacological data on Combination of Astragaloside Ⅳ with Tanshinone ⅡA inhibits the Angiotensin II-stimulated proliferation and migration of vascular smooth muscle cells via the STIM1, TRPC1/6, and NFATc3 signaling pathway

description: Objective: Astragaloside Ⅳ and Tanshinone ⅡA combined application is widely used to clinically treat coronary heart disease and atherosclerosis in China. However, it is not clear if a combined application is better than a single application of either drug alone. This study aimed to evaluate the role of TRPC/NFATc-mediated calcium signaling in the angiotensin II-induced migration and proliferation of vascular smooth muscle cells and the inhibitory effect of astragaloside Ⅳ combined with tanshinone ⅡA that occurs via the STIM1, TRPC1/ 6, and NFAT3 signaling pathway. Materials and methods: Primary VSMCs were obtained from the abdominal aortas of SD rats, cultured by tissue block adherence and identified by immunocytochemistry. VSMC migration and proliferation were investigated by transwell migration and MTT assays, respectively. Intracellular Fluo-3/AM [Ca2+]i fluorescence was detected using a laser confocal microscope. The protein expression of STIM1, TRPC1, TRPC6, calcineurin and NFATc3 was determined using a Western blot. Results: Astragaloside Ⅳ combined with tanshinone ⅡA could significantly inhibit angiotensin II-induced VSMC proliferation, migration and [Ca2+]i increases, and this combination was superior to either drug alone and was not significantly different from the TRPC blocker SKF96365. Western blotting revealed that Ang II induced obvious increases in VSMC STIM1, TRPC1, TRPC6, CaN and NFATc3 protein expression and that astragaloside Ⅳ combined with tanshinone ⅡA and SKF96365 significantly inhibited the STIM1, TRPC1, TRPC6, CaN and NFATc3 protein expression induced by angiotensin II, indicating that astragaloside Ⅳ combined with tanshinone ⅡA has the same blocking effect on TRPC-NFATc calcium signaling as SKF96365 and is better than the application of a single drug alone. Conclusions: Astragaloside Ⅳ combined with tanshinone ⅡA can inhibit the proliferation and migration of angiotensin II-induced VSMCs and is superior to the single application of either astragaloside Ⅳ or tanshinone ⅡA, and the mechanism is related to the inhibition of the STIM1, TRPC1/6, CaN, and NFATc3 calcium signaling pathway.
DOI: 10.17632/mnnktz4hkt
title: Data for: 3431114

description: A research on improving the banking hall operations of a bank using the lean approach.
DOI: 10.17632/v57bc7v59j
title: H＆E and nissl staining

description: Effect of Crocin pretreatment on histopathological changes of the hippocampus in rats in acute high altitude hypoxia
DOI: 10.17632/zs2fgw6hcr
title: Inertia-based connectivity matrices

description: Two connectivity matrices (one for schizophrenia patients and one for healthy controls) Scripts needed to perform clustering
DOI: 10.17632/22c9d4d2bs
title: FIG (5-6 and 7 (graphical abstract)) Telomere and ATM dynamics in CD4 T cell depletion in active and virus-suppressed HIV-1 infection

description: Fig.5. DNA damage response in HIV-infected SupT1 and CD4 T cells with or without RAL treatment. A-B) Confocal microscopy analysis of 53BP1 and TRF1 co-localization as a marker for dysfunctional telomere-induced foci (TIF) in SupT1 and primary CD4 T cells with HIV-1 infection. C-D) Representative overlaid histograms and summary data of mean fluorescence intensity (MFI) of telomere lengths in SupT1 cells or primary CD4 T cells, with or without HIV-1 infection and RAL treatment, as measured by Flow-FISH at the indicated times. Fig.6. The PI3K/ATM pathways are dysregulated in HIV-infected T cells and promote DDR and cell apoptosis. A) The microarray results of PI3K/ATM-related gene expressions in SupT1 cells with or without HIV-1 infection at day 3. B) RT-PCR analysis of p24 and ATM/AKT-related gene expressions in SupT1 cells with or without HIV-1 infection at day 3 and day 6 after HIV-1 infection. C) Array results of PI3K/ATM-related gene expressions in primary CD4 T cells with or without HIV-1 infection at day 5. D) RT-PCR analysis of p24 and ATM/AKT-related gene expressions in primary CD4 T cells at day 5 after HIV-1 infection. E) Western blot analysis of p24, ATM, CHK2, AKT, γH2AX, and PARP-1 expressions in SupT1 cells at the early (day 3) and late (day 6) phase of HIV-1 infection. F) Western blot analysis of p24, ATM, CHK2, AKT, γH2AX and PARP-1 expressions in primary CD4 cells at the early (day 3) and late (day 5) phase of HIV-1 infection. G) Western blot analysis of p24, ATM, pATM, CHK2, pCHK2, AKT, pAKT, γH2AX and PARP-1 expressions in SupT1 cells at day 6 after HIV infection and RAL treatment. H) Western blot analysis of p24, ATM, CHK2, pCHK2, AKT and pAKT expressions in primary CD4 T cells at day 5 after HIV infection and RAL treatment. Fig.7. Model of HIV-1 infection in CD4 T cells. The PI3K/ATM pathways are initially activated and then become deficient, causing telomeric DNA damage and erosion, CD4 T cell apoptosis and depletion, during HIV-1 infection. ART can partially reverse this process by inhibiting HIV-1 replication; however, PI3K/ATM pathways will remain dysregulated in these virus-suppressed, ART-treated CD4 T cells, and thus, the cells will survive but in an early apoptotic state in this setting of latent HIV-1 infection and/or inflammation.
DOI: 10.17632/bf6v69tdpj
title: Research data for the leakage through an incomplete-sealed well
DOI: 10.17632/ddpfchwk8c
title: Data for: Melting behavior of the Molten Salt Fast Reactor freeze-valve: a first parametric study

description: This is a declaration in which the main Author explains why no data have been uploaded.
DOI: 10.17632/44xmwp5njs
title: Data for: Major lineages of Loasaceae subfam. Loasoideae diversified during the Andean uplift

description: Research data: Concatenated alignment used to infer the divergence times and biogeographic history of Loasoideae and maximum clade credibility trees of Cornales in .tre format for callibration schemes A, B and C. Refer to the main article: Acuña, Luebert, Henning & Weigend. Major lineages of Loasaceae subfam. Loasoideae diversified during the Andean uplift. Molecular Phylogenetics and Evolution, for details.
DOI: 10.17632/5vskf7brh4
title: Data for: High compression leg bandaging prevents seated postural hypotension among elderly hospitalized patients

description: Primary database
DOI: 10.17632/c8345gkf9p
title: Data for: Evaluation of post-mortem diagnostic tests for bovine tuberculosis using Bayesian latent class analysis

description: Raw data used to evaluate tuberculosis post-mortem diagnostic tests in Brazil.
DOI: 10.17632/wyd56h8tz7
title: Data for: Effect of sugarcane genotype and maturity stage at harvest on feed intake and ruminal parameters of growing steers

description: Raw data
DOI: 10.17632/h3fkhm8gsd
title: Data for: How State Anxious Individuals Perceive Time Retrospectively: The Mediating Effect of Memory Bias

description: This is the dataset of the study "How State Anxious Individuals Perceive Time Retrospectively: The Mediating Effect of Memory Bias", which includes the raw and analyzed data from three experiments. Detailed information is available from the author on reasonable request.
DOI: 10.6084/m9.figshare.28291919
title: Ultralight wheelchair part failures are associated with sensor-monitored road shocks: A pilot study

description: Wheelchair part failures and repairs have significantly increased over the last decade, leading to severe consequences for wheelchair users. Servicing these devices by wheelchair repair technicians has reduced part failures. However, no tools or technologies have been developed to support servicing in practice. To inform servicing events, risk factors affecting wheelchair quality and reliability need to be identified. This pilot study tracks wheelchair usage for a week in the community for eight ultralight manual wheelchair users and assesses the relationship between usage variables and user-reported part failures over 20 months. The participants’ preferences for using smart technology for wheelchair servicing were evaluated. At least 73 wheelchair part failures and two adverse consequences were reported. Data analysis indicated associations between part failure frequency, usage variable of road shocks, wheelchair maintenance frequency, and the user’s demographic characteristics of training status and transportation. Six participants favored using smart technology for wheelchair servicing. This study’s findings encourage the development of usage monitoring technology and failure prediction models to support technician-led servicing and prevent wheelchair failures and user consequences.
DOI: 10.6084/m9.figshare.28291919.v1
title: Ultralight wheelchair part failures are associated with sensor-monitored road shocks: A pilot study

description: Wheelchair part failures and repairs have significantly increased over the last decade, leading to severe consequences for wheelchair users. Servicing these devices by wheelchair repair technicians has reduced part failures. However, no tools or technologies have been developed to support servicing in practice. To inform servicing events, risk factors affecting wheelchair quality and reliability need to be identified. This pilot study tracks wheelchair usage for a week in the community for eight ultralight manual wheelchair users and assesses the relationship between usage variables and user-reported part failures over 20 months. The participants’ preferences for using smart technology for wheelchair servicing were evaluated. At least 73 wheelchair part failures and two adverse consequences were reported. Data analysis indicated associations between part failure frequency, usage variable of road shocks, wheelchair maintenance frequency, and the user’s demographic characteristics of training status and transportation. Six participants favored using smart technology for wheelchair servicing. This study’s findings encourage the development of usage monitoring technology and failure prediction models to support technician-led servicing and prevent wheelchair failures and user consequences.
DOI: 10.17632/zzj883n2bc
title: Data for: Mixed messages: Assessing interactions between portion-size and energy-density perceptions in different weight and sex groups

description: RT data obtained from the Garner Classification Tasks from 70 individuals (including 36 overweight) for discriminating portion sizes and energy density of food.
DOI: 10.17632/4ggjzvjhy2
title: Data for: The Impact of Provider Education on Pediatric Palliative Care Referral

description: The aim of this project was to implement an effective educational initiative using standardized guidelines to increase provider knowledge of patients who qualify for palliative care referral, while subsequently impacting referral rates. Educational sessions were developed outlining referral recommendations from the AAP, National Hospice and Palliative Care Organization (NHPCO), and those included in the institutional policy. Presurveys and postsurveys validated by two clinical experts in the field were administered to participants at the time of the intervention. Referral rates for the organization were also collected for two months prior to the intervention, and two months following the intervention.
DOI: 10.17632/5c7d3ktnm4
title: Data for: Grouping Detection and Forecasting Security Controls Using Unrestricted Cooperative Bargains

description: data from three entire days: (1) before Black Friday (Nov/21/2014); during Black Friday (Nov/28/2014); and (3) after Black Friday (Dec/05/2014). There are different sections of network traffic: (1) normal; (2) DDoS; (3) Flash Crowd; and (4) Flash Crowd + DDoS which is a very rare scenario. Since the IP of hosts are confidential, they are masked by letters (one letter represents just one number). The data in this repository is related to site P (78 samples with around 500,00 records each). The dataset is available in the CSV format (text). The fields are limited by apostrophe, separated by semicolon and compressed with 7z. Mirror at: https://uspbr-my.sharepoint.com/:f:/g/personal/and1970_usp_br/EvRKMh0d3slPpDkdZgBuR-oBULsPbgnHvnsqC9P5UzBFOQ?e=TAgPyc . A complete version of this dataset with all the e-commerce sites can be found at: https://uspbr-my.sharepoint.com/:f:/g/personal/and1970_usp_br/EvYstyiZiWdEhOfiI21IOWwB1lCHXsrNUKPpBx7-z1rnWQ?e=efkCVa Please in case of use, cite our original researches: 1) Grouping Detection and Forecasting Security Controls Using Unrestricted Cooperative Bargains; 2) A Proposal to Distinguish DDoS Traffic in Flash Crowd Environments.
DOI: 10.17632/gdr6pbmb3w
title: Data for: High Versus Low Mean Arterial Pressures in Hepatorenal Syndrome: A Randomized Controlled Trial

description: This is some of our processed data.
DOI: 10.17632/jx7b5t4f6j
title: Design files and LabVIEW VIs for the IceDrone

description: These design files and LabVIEW VIs contained in this dataset allow sea ice and iceberg researchers to replicate the IceDrone. The IceDrone is a student-built, unmanned ice sampling system that was designed to acquire ice samples from high-risk environments, like icebergs and thin sea ice. IceDrone is relatively small and portable and can be operated with little support infrastructure, which frees up research equipment on icebreakers, like baskets and helicopters, for other research activities. IceDrone is built around the commercially available DJI Matrice 600 Pro (M600) hexcopter. The M600 is modified to carry a custom ice coring system and landing gear. The files presented here are separated into versions. Versions 1 and 2 include the initial design, and upgrades that were made after a field test, respectively. Version 1 includes the basic design files and describes the overall construction of IceDrone. Version 2 includes upgrades to the ice core drill design, laser range finders to regulate descent speed, automated drill motor control, vibration dampening for the camera/gimbal system, and a 3D printed enclosure for the electronics.
DOI: 10.17632/xtrmcz67kh
title: Data for: Instrumental and clinical comparison between laryngeal mask airway Proseal and Supreme in pediatric patients
DOI: 10.17632/yvjkr7w7ys
title: Data for: Multilocus phylogeny of Oreochromis cichlid fishes reveals reticulate evolution and recent colonisation of extreme aquatic environments

description: Nexus files for mtDNA and nuDNA datasets
DOI: 10.17632/g56ndmwwbh
title: Data for: Application of ADVANTG to the JET3 - NEXP streaming benchmark experiment

description: Final results showing the application of ADVANTG code to a complex neutron streaming problem in a realistic fusion geometry. Results include a comparison of ADVANTG accelerated simulation results to analog results, results from different institutions and to experimental results.
DOI: 10.17632/w83h66729n
title: Data belonging to: "Direct visualization of native CRISPR target search in live bacteria reveals Cascade DNA surveillance mechanism"

description: Dataset includes D* coefficient lists, all localizations/tracks, interference data for different conditions and further data used in all figures of the manuscript. For raw image files (due to size restrictions not uploaded here) ask one of the corresponding authors of the paper. For further details see STAR methods of the paper.
DOI: 10.17632/2x95ff2b9z
title: Data for: INCREMENTAL PROCEDURE METHOD FOR THE ANALYSIS OF GROUND REACTION DUE TO EXCAVATION OF A CIRCULAR TUNNEL BY CONSIDERING THE EFFECT OF OVERBURDEN DEPTH

description: In this article, one can find the output diagrams that include the distribution of vertical stress (v), radial stress (r), tangential stress () and radial displacement (ur) along the distance ratio (r/R), and the input data that contain Tunnel excavation radius, R (m); Depth of tunnel crown, h (m); In-situ stress ratio, Ko; Unit weight, g (MPa/m); Elastic modulus, E (MPa); Poisson's ratio, ; Internal friction angle,  (deg.); Dilation angle,  (deg.); Cohesion, c (MPa); Clockwise angle in polar coordinate , (deg.); and Confinement loss,  .
DOI: 10.17632/b5d3w3hjyj
title: RNAseq in TOX up- and down-regulated mycosis fungoides cells

description: We up-regulated (TOX vs G) and down-regulated (SH1&SH2 vs SHV) TOX expression in Myla cell line, and performed RNA sequencing to analyse TOX-related transcriptome differences in these cells. Over-expression and suppression of TOX led to mRNA regulation of multiple genes including PRKAR2B.
DOI: 10.17632/h9v3s74fnt
title: Data for: The effect of successive uniaxial and biaxial cyclic loading on the fracture resistance of limestone samples

description: The purpose of the tests: a comparative assessment of the damage and resistance of limestone to the destructive effect under uniaxial and biaxial cyclic mechanical loads. Test data for two 50x50x25 mm limestone samples under uniaxial and biaxial sequential cyclic compressive loading are presented. The maximum stress in the cycle is 10 MPa. Sample LM1 was tested in series of 20 cycles in one direction. Each series of 20 cycles for the LM2 sample consisted of two subseries of 10 cycles, the second of which was carried out in the direction perpendicular to the direction of the first subseries. Loading was carried out before the destruction of the samples. Data are presented in two folders designated according to samples and test modes LM1 and LM2 respectively. Each of these folders contains subfolders directly with the corresponding data. Each subfolder contains three data files in which the registration results are recorded: - a file with the letters AE with data on the number of pulses of acoustic emission; - a file with the letter P with data on the load on the sample; - a file with the letter T with data on the strain gauge deformations oriented along the direction of the first loading in the series. For visualization and data processing, each folder contains programs written in the Mathcad software, the name of which contains the word Test. The data of sample LM1 are presented as follows. Folder LM1_8 - test data at a voltage of 8 MPa and a number of cycles of 20 (estimated loads). Folder LM1_10_20 - test data at a voltage of 10 MPa with cycle numbers from 1 to 20. Folder LM1_10_40 - test data at a stress of 10 MPa with cycle numbers from 21 to 40; further similarly to the folder LM1_10_122, when the destruction of the sample occurred. The data of LM2 sample are presented for those series when loading was carried out along the orientation direction of the strain gauge glued to the sample. Folder LM2_10_10 - test data at a stress of 10 MPa with load numbers from 1 to 10. Folder LM2_10_30 - test data at a voltage of 10 MPa with load numbers from 21 to 30, etc. to the folder LM2_10_110. It contains data on the subseries of loading when the destruction of the sample occurred. As a result, we obtained graphs of changes in the loads and deformations of the sample over time, as well as graphs of changes in the number of AE pulses up to failure. The study was supported by the Russian Foundation for Basic Research, grant No. 17-05-00570.
DOI: 10.17632/23j8ktc8yr
title: Data for: Prediction of high-resolution reservoir facies and permeability, an integrated approach in the Irwin River Coal Measures Formation, Perth Basin, Western Australia

description: Attached the LAS files for the raw log/core data and the results including the facies logs and the predicted permeability log
DOI: 10.17632/2wypf6vj34
title: Data for: 1D Thermal Creep Channel Flow in the BGK Approximation by Adding and Doubling

description: fuck you
DOI: 10.17632/cg4zm2wsz2
title: Achanthes trinodis

description: The deposition of silica by diatoms may also prove to be of utility to nanotechnology. Diatom cells repeatedly and reliably manufacture valves of various shapes and sizes, potentially allowing diatoms to manufacture micro- or nano-scale structures which may be of use in a range of devices, including: optical systems; semiconductor nanolithography; and even vehicles for drug delivery. With an appropriate artificial selection procedure, diatoms that produce valves of particular shapes and sizes might be evolved for cultivation in chemostat cultures to mass-produce nanoscale components
DOI: 10.17632/kddjgvbrhj
title: Fine scale assemblage structure of benthic invertebrate megafauna on the North Pacific seamount Mokumanamana

description: Raw and standardized counts of benthic invertebrates from the Northwestern Hawiian seamount Mokumanamana from AUV still images. This data is structured to compare invertebrate communities between depths and sides of a single deep-sea feature. One side has more depth bins counted than the other two, due to analysis that found every 50 m of depth was not necessary to see differences in community.. Standardized counts are divided by the number of images in each transect. Also included are two sets of R code for all analyses done in R, one for the S362 with more depth bins, and one for the whole of the seamount at the same depths.
DOI: 10.17632/8szgmx5bk9
title: Data for: Volcano-hydrothermal inflation revealed through spatial variation in stress field in Tatun Volcano Group, Northern Taiwan
DOI: 10.17632/9ybkkwmrpt
title: Data for: The Social Lives of Married Women: Peer Effects in Female Autonomy and Children's Food Consumption
DOI: 10.17632/c96zp8bbmg
title: Data for: Phosphorus fractions in sediments and their relevance for historical lake eutrophication in the Ponte Tresa basin (Lake Lugano, Switzerland) since 1959
DOI: 10.17632/g5ypj2dyj2
title: Mechanism of DNA end sensing and processing by the Mre11-Rad50 complex. Kaeshammer et al.

description: Raw images describing the biochemistry of bacterial MR as published in Mechanism of DNA end sensing and processing by the Mre11-Rad50 complex. Kaeshammer et al.
DOI: 10.17632/x94fnvn5kb
title: Data for: Laser Firing in Silicon Heterojunction Interdigitated Back Contact Architecture for Low Contact Resistance

description: The manuscript details a new laser firing technique applied to completed SHJ-IBC solar cells on polycrystalline silicon on glass substrates, in order to lower contact resistance and improve fill-factor and efficiency.
DOI: 10.17632/2tyyrf5cfx
title: Data for: Household solid waste characterization in Tandil (Argentina): socioeconomic, institutional, temporal and cultural aspects influencing waste quantity and composition

description: Results of a stratified door-to-door solid waste characterization performed in the city of Tandil, Buenos Aires (Argentina).
DOI: 10.17632/dyt9m5s2cj
title: Data for: An expert-based approach to assess the potential for local people engagement in nature conservation: the case study of the Niassa National Reserve in Mozambique
DOI: 10.17632/rkswngdh5f
title: Data for: Application of electrical resistivity method in the characterization of 2D desiccation cracking process of clayey soil
DOI: 10.17632/9zfrh6r4p9
title: Seattle bikeshare survey

description: A survey of Seattle bikesharing users and potential users was conducted in February - March 2018. Respondents included users of Pronto (222 respondents) and dockless bikesharing (505 respondents), and potential Seattle bikesharing users who had not yet used any Seattle bikesharing offerings. The survey was hosted on Google Forms and was distributed through several online platforms: UW Today / UW News, the Seattle Bike Blog, and social media. As a participation incentive, respondents were entered in a drawing for a premium bag (valued at $160) from Swift Industries, a Seattle company. The survey included sections on Pronto, dockless bikesharing, and demographics.