cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.4602511
title: Data supporting the results presented in Stephenson et al. from Host heterogeneity affects both parasite transmission to and fitness on subsequent hosts

description: This file contains the raw data from the experiment described in Stephenson et al
DOI: 10.6084/m9.figshare.4602511.v1
title: Data supporting the results presented in Stephenson et al. from Host heterogeneity affects both parasite transmission to and fitness on subsequent hosts

description: This file contains the raw data from the experiment described in Stephenson et al
DOI: 10.15131/shef.data.4602472
title: The Standardised Tibia

description: This model was originally developed by Hans Gray and Riche Gill, at that time working at the Orthopaedic Oxford Engineering Centre, University of Oxford (UK), in the frame of a collaboration with Luca Cristofolini and Marco Viceconti, at that time based at the Medical Technology Lab of the Rizzoli Orthopaedic Institute, in Italy. The research that motivated the generation of this model was published here [ref1]. The fileset contains two STL surfaces representing the inner and outer surface obtained by segmenting a clinical CT of a composite tibia model 3101, at that time produced by Pacific Research Laboratories, Vashon, Washington, USA, that was then bought by Sawbones . The fileset was originally made available as Open Access to the research community in 2004 as part of the now defunct BEL Repository, which was then absorbed into the also now defunct PhysiomeSpace repository.
DOI: 10.15131/shef.data.4602472.v1
title: The Standardised Tibia

description: This model was originally developed by Hans Gray and Riche Gill, at that time working at the Orthopaedic Oxford Engineering Centre, University of Oxford (UK), in the frame of a collaboration with Luca Cristofolini and Marco Viceconti, at that time based at the Medical Technology Lab of the Rizzoli Orthopaedic Institute, in Italy. The research that motivated the generation of this model was published here [ref1]. The fileset contains two STL surfaces representing the inner and outer surface obtained by segmenting a clinical CT of a composite tibia model 3101, at that time produced by Pacific Research Laboratories, Vashon, Washington, USA, that was then bought by Sawbones . The fileset was originally made available as Open Access to the research community in 2004 as part of the now defunct BEL Repository, which was then absorbed into the also now defunct PhysiomeSpace repository.
DOI: 10.6084/m9.figshare.4602334
title: SF-6D utility values for better- and worse-seeing eye for health states based on the Snellen equivalent in patients with Age-Related Macular Degeneration

description: <b><i>Objective</i></b><b>:</b> Economic evaluations in wet age-related macular degeneration (ARMD) tend to overestimate the effect of interventions, in terms of quality of life (QOL), as the interaction between the worse seeing eye (WSE) and the better seeing eye (BSE) is not incorporated. Some ad hoc modelling approaches are published to incorporate this interaction. In this investigation we set out to provide SF-6D utility estimates for health states of ARMD, that incorporated this interaction based on data of a clinical trial. <b><i>Methods</i></b><b>:</b> SF-6D data of 191 ARMD patients (&gt;65 years) were used to fill health states defined by the combination of WSE and BSE using Snellen equivalents; no visual loss (≥20/40), mild-moderate (&lt;20/40 - &gt;20/200) and severe (≤20/200). <b><i>Results</i></b>: We found a consistent linear relation between health states and SF-6D and found an interaction between changes in the WSE and BSE. In this elderly population, co-morbidity did produce considerable background noise. <b><i>Conclusion</i>: </b>We provide utility values for economic modeling in ARMD when direct utility measures are lacking. Besides, the results presented here provide a solution to overcome overestimation of the effect of interventions in ARMD and will result in more valid and more conservative estimates of the effects.
DOI: 10.6084/m9.figshare.4602337
title: Male professional footballers’ experiences of mental health difficulties and help-seeking

description: <b>Objectives:</b> Male professional footballers (soccer) represent an at-risk population of developing mental health difficulties and not accessing professional support. One in four current footballers report mental health difficulties. Higher prevalence is reported after retirement. This qualitative study aimed to provide in-depth insight into male professional footballers’ lived experiences of mental health difficulties and help-seeking. <b>Methods:</b> Seven participants were interviewed. Data were analysed using interpretative phenomenological analysis. <b>Results:</b> One superordinate theme emerged; ‘Survival’. This related to survival in the professional football world, of mental health difficulties and after transition into the ‘real world’. Six subordinate themes are explored alongside literature pertaining to male mental health, identity, injury, transition, and emotional development. Shame, stigma, fear and level of mental health literacy (knowledge of mental health and support) were barriers to help-seeking. <b>Conclusion:</b> Support for professional footballers’ mental wellbeing requires improvement. Recommendations are made for future research, mental health education and support.
DOI: 10.6084/m9.figshare.4602337.v1
title: Male professional footballers’ experiences of mental health difficulties and help-seeking

description: <b>Objectives:</b> Male professional footballers (soccer) represent an at-risk population of developing mental health difficulties and not accessing professional support. One in four current footballers report mental health difficulties. Higher prevalence is reported after retirement. This qualitative study aimed to provide in-depth insight into male professional footballers’ lived experiences of mental health difficulties and help-seeking. <b>Methods:</b> Seven participants were interviewed. Data were analysed using interpretative phenomenological analysis. <b>Results:</b> One superordinate theme emerged; ‘Survival’. This related to survival in the professional football world, of mental health difficulties and after transition into the ‘real world’. Six subordinate themes are explored alongside literature pertaining to male mental health, identity, injury, transition, and emotional development. Shame, stigma, fear and level of mental health literacy (knowledge of mental health and support) were barriers to help-seeking. <b>Conclusion:</b> Support for professional footballers’ mental wellbeing requires improvement. Recommendations are made for future research, mental health education and support.
DOI: 10.6084/m9.figshare.4602313
title: gbif.csv

description: Gbif data set <br>
DOI: 10.6084/m9.figshare.4602313.v1
title: gbif.csv

description: Gbif data set <br>
DOI: 10.6084/m9.figshare.4602334.v2
title: SF-6D utility values for better- and worse-seeing eye for health states based on the Snellen equivalent in patients with Age-Related Macular Degeneration

description: <b><i>Objective</i></b><b>:</b> Economic evaluations in wet age-related macular degeneration (ARMD) tend to overestimate the effect of interventions, in terms of quality of life (QOL), as the interaction between the worse seeing eye (WSE) and the better seeing eye (BSE) is not incorporated. Some ad hoc modelling approaches are published to incorporate this interaction. In this investigation we set out to provide SF-6D utility estimates for health states of ARMD, that incorporated this interaction based on data of a clinical trial. <b><i>Methods</i></b><b>:</b> SF-6D data of 191 ARMD patients (&gt;65 years) were used to fill health states defined by the combination of WSE and BSE using Snellen equivalents; no visual loss (≥20/40), mild-moderate (&lt;20/40 - &gt;20/200) and severe (≤20/200). <b><i>Results</i></b>: We found a consistent linear relation between health states and SF-6D and found an interaction between changes in the WSE and BSE. In this elderly population, co-morbidity did produce considerable background noise. <b><i>Conclusion</i>: </b>We provide utility values for economic modeling in ARMD when direct utility measures are lacking. Besides, the results presented here provide a solution to overcome overestimation of the effect of interventions in ARMD and will result in more valid and more conservative estimates of the effects.
DOI: 10.6084/m9.figshare.4602301
title: Supporting datasets for Comparison of Multi-locus Sequence Typing software for next generation sequencing data

description: To test the accuracy of MLST applications, we have constructed two datasets of simulated reads in FASTQ format. The first has perfect reads over the MLST genes, plus a flanking region (based on the Salmonella Typhi CT18 reference) in varying levels of coverage from 1 to 30. This allows for us to see at what point each software application can accurately detect an allele.The second dataset is similar to the first, but contains 2 Salmonella samples Salmonella Typhi CT18 and Salmonella Weltevreden, with the samples mixed in varying ratios. This allows us to see at what point software applications detect that there is a mixed allele/contamination.
DOI: 10.6084/m9.figshare.4602334.v1
title: AMD_qol.sav

description: <b><i>Objective</i></b><b>:</b> Economic evaluations in wet age-related macular degeneration (ARMD) tend to overestimate the effect of interventions, in terms of quality of life (QOL), as the interaction between the worse seeing eye (WSE) and the better seeing eye (BSE) is not incorporated. Some ad hoc modelling approaches are published to incorporate this interaction. In this investigation we set out to provide SF-6D utility estimates for health states of ARMD, that incorporated this interaction based on data of a clinical trial. <b><i>Methods</i></b><b>:</b> SF-6D data of 191 ARMD patients (&gt;65 years) were used to fill health states defined by the combination of WSE and BSE using Snellen equivalents; no visual loss (≥20/40), mild-moderate (&lt;20/40 - &gt;20/200) and severe (≤20/200). <b><i>Results</i></b>: We found a consistent linear relation between health states and SF-6D and found an interaction between changes in the WSE and BSE. In this elderly population, co-morbidity did produce considerable background noise. <b><i>Conclusion</i>: </b>We provide utility values for economic modeling in ARMD when direct utility measures are lacking. Besides, the results presented here provide a solution to overcome overestimation of the effect of interventions in ARMD and will result in more valid and more conservative estimates of the effects.
DOI: 10.6084/m9.figshare.4602124
title: The genera <i>Melanothamnus</i> Bornet & Falkenberg and <i>Vertebrata</i> S.F. Gray constitute well-defined clades of the red algal tribe Polysiphonieae (Rhodomelaceae, Ceramiales)

description: <i>Polysiphonia</i> is the largest genus of red algae, and several schemes subdividing it into smaller taxa have been proposed since its original description. Most of these proposals were not generally accepted, and currently the tribe Polysiphonieae consists of the large genus <i>Polysiphonia</i> (190 species), the segregate genus <i>Neosiphonia</i> (43 species) and 13 smaller genera (&lt; 10 species each). In this paper, phylogenetic relationships of the tribe Polysiphonieae are analysed, with particular emphasis on the genera <i>Carradoriella, Fernandosiphonia, Melanothamnus, Neosiphonia, Polysiphonia sensu stricto</i>, <i>Streblocladia</i> and <i>Vertebrata</i>. We evaluated the consistency of 14 selected morphological characters in the identified clades. Based on molecular phylogenetic (<i>rbc</i>L and 18S genes) and morphological evidence, two speciose genera are recognized: <i>Vertebrata</i> (including the type species of the genera <i>Ctenosiphonia, Enelittosiphonia, Boergeseniella</i> and <i>Brongniartella</i>) and <i>Melanothamnus</i> (including the type species of the genera <i>Fernandosiphonia</i> and <i>Neosiphonia</i>). Both genera are distinguished from other members of the Polysiphonieae by synapomorphic characters, the emergence of which could have provided evolutionarily selective advantages for these two lineages. In <i>Vertebrata</i> trichoblast cells are multinucleate, possibly associated with the development of extraordinarily long photoprotective trichoblasts. <i>Melanothamnus</i> has 3-celled carpogonial branches and plastids lying exclusively on radial walls of the pericentral cells, which similarly may improve resistance to damage caused by excessive light. Other relevant characters that are constant in each genus are also shared with other clades. The evolutionary origin of the genera <i>Melanothamnus</i> and <i>Vertebrata</i> is estimated as 75.7–95.78 and 90.7–138.66 Ma, respectively. Despite arising in the Cretaceous, before the closure of the Tethys Seaway, <i>Melanothamnus</i> is a predominantly Indo-Pacific genus and its near-absence from the north-eastern Atlantic is enigmatic. The nomenclatural implications of this work are that 46 species are here transferred to <i>Melanothamnus</i>, six species are transferred to <i>Vertebrata</i>, and 13 names are resurrected for <i>Vertebrata</i>.
DOI: 10.6084/m9.figshare.4602124.v1
title: The genera <i>Melanothamnus</i> Bornet & Falkenberg and <i>Vertebrata</i> S.F. Gray constitute well-defined clades of the red algal tribe Polysiphonieae (Rhodomelaceae, Ceramiales)

description: <i>Polysiphonia</i> is the largest genus of red algae, and several schemes subdividing it into smaller taxa have been proposed since its original description. Most of these proposals were not generally accepted, and currently the tribe Polysiphonieae consists of the large genus <i>Polysiphonia</i> (190 species), the segregate genus <i>Neosiphonia</i> (43 species) and 13 smaller genera (&lt; 10 species each). In this paper, phylogenetic relationships of the tribe Polysiphonieae are analysed, with particular emphasis on the genera <i>Carradoriella, Fernandosiphonia, Melanothamnus, Neosiphonia, Polysiphonia sensu stricto</i>, <i>Streblocladia</i> and <i>Vertebrata</i>. We evaluated the consistency of 14 selected morphological characters in the identified clades. Based on molecular phylogenetic (<i>rbc</i>L and 18S genes) and morphological evidence, two speciose genera are recognized: <i>Vertebrata</i> (including the type species of the genera <i>Ctenosiphonia, Enelittosiphonia, Boergeseniella</i> and <i>Brongniartella</i>) and <i>Melanothamnus</i> (including the type species of the genera <i>Fernandosiphonia</i> and <i>Neosiphonia</i>). Both genera are distinguished from other members of the Polysiphonieae by synapomorphic characters, the emergence of which could have provided evolutionarily selective advantages for these two lineages. In <i>Vertebrata</i> trichoblast cells are multinucleate, possibly associated with the development of extraordinarily long photoprotective trichoblasts. <i>Melanothamnus</i> has 3-celled carpogonial branches and plastids lying exclusively on radial walls of the pericentral cells, which similarly may improve resistance to damage caused by excessive light. Other relevant characters that are constant in each genus are also shared with other clades. The evolutionary origin of the genera <i>Melanothamnus</i> and <i>Vertebrata</i> is estimated as 75.7–95.78 and 90.7–138.66 Ma, respectively. Despite arising in the Cretaceous, before the closure of the Tethys Seaway, <i>Melanothamnus</i> is a predominantly Indo-Pacific genus and its near-absence from the north-eastern Atlantic is enigmatic. The nomenclatural implications of this work are that 46 species are here transferred to <i>Melanothamnus</i>, six species are transferred to <i>Vertebrata</i>, and 13 names are resurrected for <i>Vertebrata</i>.
DOI: 10.6084/m9.figshare.4602085
title: Supplementary Material for: Hochuekkito, a Japanese Herbal Medicine, Restores Metabolic Homeostasis between Mitochondrial and Glycolytic Pathways Impaired by Influenza A Virus Infection

description: <b><i>Background:</i></b> Hochuekkito (HKT), a traditional Japanese herbal medicine (Kampo), has been used to treat symptoms of several diseases. In a recent clinical study, HKT was shown to be protective against the influenza virus infection. However, the underlying mechanism of the prophylactic effect is not clear. Mitochondrial and glycolytic pathways play important roles in cellular energy metabolism to maintain biological functions. These metabolic pathways are affected by the influenza virus infection. In this study, we examined the relationship between the preventive effects of HKT against the influenza virus infection and cellular energy metabolism in mitochondria and glycolysis using Madin-Darby canine kidney cells and influenza A/PR/8/34 (H1N1) virus (IAV). <b><i>Methods:</i></b> Mitochondrial and glycolytic metabolic pathways were evaluated on the basis of the oxygen consumption rate (OCR) and extracellular acidification rate (ECAR), respectively, using the XF24 Extracellular Analyzer. <b><i>Results:</i></b> The OCR/ECAR ratio in IAV-infected cells was lower than that in control cells. Cells that were treated with HKT before IAV infection showed a metabolic pattern similar to that in the control cells (increase in both OCR and ECAR). <b><i>Conclusions:</i></b> Our results suggest that HKT not only activates both mitochondrial and glycolytic energy metabolism in IAV-infected cells but also helps maintain metabolic homeostasis similar to that in noninfected cells.
DOI: 10.6084/m9.figshare.4602019
title: Experiment ESWC2017

description: Dataset from an evaluation of ontology learning process in semantic web domain
DOI: 10.6084/m9.figshare.4602085.v2
title: Supplementary Material for: Hochuekkito, a Japanese Herbal Medicine, Restores Metabolic Homeostasis between Mitochondrial and Glycolytic Pathways Impaired by Influenza A Virus Infection

description: <b><i>Background:</i></b> Hochuekkito (HKT), a traditional Japanese herbal medicine (Kampo), has been used to treat symptoms of several diseases. In a recent clinical study, HKT was shown to be protective against the influenza virus infection. However, the underlying mechanism of the prophylactic effect is not clear. Mitochondrial and glycolytic pathways play important roles in cellular energy metabolism to maintain biological functions. These metabolic pathways are affected by the influenza virus infection. In this study, we examined the relationship between the preventive effects of HKT against the influenza virus infection and cellular energy metabolism in mitochondria and glycolysis using Madin-Darby canine kidney cells and influenza A/PR/8/34 (H1N1) virus (IAV). <b><i>Methods:</i></b> Mitochondrial and glycolytic metabolic pathways were evaluated on the basis of the oxygen consumption rate (OCR) and extracellular acidification rate (ECAR), respectively, using the XF24 Extracellular Analyzer. <b><i>Results:</i></b> The OCR/ECAR ratio in IAV-infected cells was lower than that in control cells. Cells that were treated with HKT before IAV infection showed a metabolic pattern similar to that in the control cells (increase in both OCR and ECAR). <b><i>Conclusions:</i></b> Our results suggest that HKT not only activates both mitochondrial and glycolytic energy metabolism in IAV-infected cells but also helps maintain metabolic homeostasis similar to that in noninfected cells.
DOI: 10.6084/m9.figshare.4602016
title: EXCEED - The Extreme Climate Event Database

description: Extreme Climate Event Database is a picture database intended to induce emotionally salient stimuli reactions in the context of natural hazards associated with global climate change and related extreme events.<br>The creation of the database was motivated by the need to better understand the impact that the increase in natural disasters worldwide has on human emotional reactions.<br>This new database consists of 150 pictures divided into three categories: two negative categories that depict images of floods and droughts, and a neutral category composed of inanimate objects.<br>Each image receives an abbreviation identification letter for the category that it belongs to, followed by a crescent number within the group, the respective attribution credit and creative common (CC) license. <br>The letter N represents neutral pictures (range: N01 to N50), FL designates the flood group (range FL01 to FL50), and DR designates drought pictures (range DR01 to DR50). <br>All pictures are in JPEG format; however, the resolution and dimensions could vary between pictures.<br><br>All EXCEED images are under Creative Common (CC) license, and each image is under specific license according to restrictions of modifications and use in commercial settings.<br><br>When using any image from EXCEED, one must be careful to individual license for each picture as well for the credits for the owner and EXCEED.<br>Access &lt; https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0204093 &gt; to read about the development and validation of EXCEED.<br>
DOI: 10.6084/m9.figshare.4602019.v2
title: Experiment ESWC2017

description: Dataset from an evaluation of ontology learning process in semantic web domain
DOI: 10.6084/m9.figshare.4602001
title: Clinical trials to compare two treatments

description: Clinical trials to compare two treatments
DOI: 10.6084/m9.figshare.4602001.v1
title: Clinical trials to compare two treatments

description: Clinical trials to compare two treatments
DOI: 10.6084/m9.figshare.4602019.v1
title: Experiment ESWC2017

description: Dataset from an evaluation of ontology learning process in semantic web domain
DOI: 10.6084/m9.figshare.4601983
title: Table S4b: U/Pb data for analyses by SHRIMP. Uranium–lead zircon systematics in the Sudbury impact crater-fill: implications for target lithologies and crater evolution

description: Table S4b: U/Pb data for analyses by SHRIMP
DOI: 10.6084/m9.figshare.4601983.v1
title: Table S4b: U/Pb data for analyses by SHRIMP. Uranium–lead zircon systematics in the Sudbury impact crater-fill: implications for target lithologies and crater evolution

description: Table S4b: U/Pb data for analyses by SHRIMP
DOI: 10.6084/m9.figshare.4601977
title: Table S2. Uranium–lead zircon systematics in the Sudbury impact crater-fill: implications for target lithologies and crater evolution

description: Table S2: Trace element (ppb) and Pb-isotope data of Neoarchean and Paleoproterozoic granitoid and gneiss feldspar
DOI: 10.6084/m9.figshare.4601974
title: Table S1: Sample information. Uranium–lead zircon systematics in the Sudbury impact crater-fill: implications for target lithologies and crater evolution

description: Table S1: Sample information.
DOI: 10.6084/m9.figshare.4601977.v1
title: Table S2. Uranium–lead zircon systematics in the Sudbury impact crater-fill: implications for target lithologies and crater evolution

description: Table S2: Trace element (ppb) and Pb-isotope data of Neoarchean and Paleoproterozoic granitoid and gneiss feldspar
DOI: 10.6084/m9.figshare.4601965
title: Table S4a: U/Pb data for analyses by LA-ICPMS and SIMS (12JAP014). Uranium–lead zircon systematics in the Sudbury impact crater-fill: implications for target lithologies and crater evolution

description: Table S4a: U/Pb data for analyses by LA-ICPMS and SIMS (12JAP014)
DOI: 10.6084/m9.figshare.4601968
title: Table S3. Uranium–lead zircon systematics in the Sudbury impact crater-fill: implications for target lithologies and crater evolution

description: Table S3: Isotopic modelling parameters
DOI: 10.6084/m9.figshare.4601974.v1
title: Table S1: Sample information. Uranium–lead zircon systematics in the Sudbury impact crater-fill: implications for target lithologies and crater evolution

description: Table S1: Sample information.
DOI: 10.6084/m9.figshare.4601965.v1
title: Table S4a: U/Pb data for analyses by LA-ICPMS and SIMS (12JAP014). Uranium–lead zircon systematics in the Sudbury impact crater-fill: implications for target lithologies and crater evolution

description: Table S4a: U/Pb data for analyses by LA-ICPMS and SIMS (12JAP014)