cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.10592687
title: Supplementary Material for: Impact of Serum Bicarbonate Levels on Muscle Mass and Kidney Function in Pre-Dialysis Chronic Kidney Disease Patients

description: <b><i>Background:</i></b> Treatment of metabolic acidosis to target the higher serum bicarbonate level than guideline recommendation may downregulate muscle protein degradation and improve renal function among chronic kidney disease (CKD) patients. We conducted a study to test the effects of increased serum bicarbonate level on muscle parameters, nutrition, and renal function in pre-dialysis CKD patients. <b><i>Methods:</i></b> This was a randomized, controlled study. CKD stage 3–4 patients with serum HCO<sub>3</sub><sup>–</sup> &lt;22 mEq/L were randomized to either receive oral sodium bicarbonate with high target bicarbonate level of 25 ± 1 or standard level of 22 ± 1 mEq/L as control group using protocol-based titration of dosage adjustment. The changes of muscle mass measured by bioelectrical impedance analysis (BIA), muscle strength by hand grip dynamometer, estimated glomerular filtration rate (eGFR) using CKD-Epidemiology Collaboration equation, nutritional markers, and muscle-related biomarkers were determined. Data at baseline and after 4 months of sodium bicarbonate supplementation were compared between groups using Student <i>t</i> test or chi-square test as appropriate. <b><i>Results:</i></b> Forty-two patients completed the study (<i>n</i> = 21 per group). The mean age and eGFR were 61.2 ± 9.8 years and 32.4 ± 14.1 mL/min respectively. Serum bicarbonate levels at baseline were 21.0 ± 2.1 mEq/L. Baseline data including sex, diabetes, serum bicarbonate level, creatinine, and blood pressure were similar. After 4 months of treatment, the average serum bicarbonate levels in both groups were 24.0 ± 1.4 and 20.7 ± 2.3 mEq/L (<i>p</i> &lt; 0.001). Both BIA-derived total-body muscle mass and appendicular lean balance were increased at 4 months in the higher bicarbonate group (26.0 ± 5.3 to 26.7 ± 5.5 kg, <i>p</i> = 0.04 and 19.8 ± 4.1 to 20.7 ± 4.4 kg, <i>p</i> = 0.06, respectively) despite comparable body weight and protein intake. Patients in the high bicarbonate group had a significant reduction of plasma myostatin levels, a surrogate of muscle degradation, at the study exit after adjusting for baseline values (–3,137.8; 95% CI –6,235.3 to –40.4 pg/mL, <i>p</i>= 0.04), but unaltered insulin-like growth factor-1 level, as the mediator of muscle cell growth, (141 [106–156] to 110 [87–144] ng/mL, <i>p</i> = 0.13) compared to the control group. Muscle strength, eGFR as well as serum prealbumin were not significantly different between 2 groups (<i>p</i> &gt; 0.05). Neither worsening hypertension nor congestive heart failure was found throughout the study. <b><i>Conclusion:</i></b> Bicarbonate supplementation to achieve the serum level ∼24 mEq/L demonstrates better muscle mass preservation in patients with pre-dialysis CKD. The impact of alkaline therapy on renal function may require a longer period of study.
DOI: 10.6084/m9.figshare.10590830

description: The file contains respective title and URL of the considered 165 articles used in the investigation titled "A Review on the Prevalence of Machine Learning Techniques in Software Defect Prediction".
DOI: 10.6084/m9.figshare.10590830.v1
title: 165_Articles.xlsx

description: The file contains respective title and URL of the considered 165 articles used in the investigation titled "A Review on the Prevalence of Machine Learning Techniques in Software Defect Prediction".
DOI: 10.6084/m9.figshare.10580921
title: Characteristic dietary habits associated with high values of estimated 24-hours urinary sodium excretion and sodium-to-potassium ratio assessed by age group among the residents of a rural town in Japan

description: Excess salt intake causes hypertension and cardiovascular disease (CVD). We examined estimated 24-h urinary sodium (Na) excretion and sodium-to-potassium (Na/K) ratio and analyzed the association between estimated 24-h urinary salt excretion (urinary salt excretion) and dietary habits by age group to develop effective public health programs to promote salt reduction. A total of 4,051 subjects aged 30–74 years old received information during periodic health checkups. In the analysis, 1,202 subjects without hypertension whose urine samples and dietary habits were confirmed (29.7%; 483 men and 719 women) were included. The median urinary salt excretion was 9.1 g/day in men and 8.6 g/day in women. Daily intake of soups in men aged &lt;50 years old and daily intake of beans, soups, or pickles in women aged ≥70 years old were associated with high values of urinary salt excretion (<i>p</i> = .03, <i>p</i> &lt; .01, <i>p</i> = .01, and <i>p</i> = .02, respectively). The median urinary Na/K ratio (mEq/mEq) was 4.4 in both men and women. Daily intake of vegetables in men aged &lt;50 years old and more than 3 days/week intake of fruit in women aged 50–59 and 60–69 years old were associated with lower values of urinary Na/K ratio (<i>p</i> = .03, <i>p</i> &lt; .01, and <i>p</i> &lt; .01, respectively). These findings revealed that dietary salt reduction should be promoted according to age group with regard to differences in dietary habits associated with high values of estimated 24-h urinary Na excretion and urinary Na/K ratio.
DOI: 10.6084/m9.figshare.10582124
title: data for logistic regression analyses (exp 1) 'emotional faces and biological motion study'

description: data from exp 1 is given in a form ready for logistic regression analyses <br><b>*** important ***</b>the logistic-regression ready data from exp 2 can be generated through the R codes for experiment 2
DOI: 10.6084/m9.figshare.10580921.v1
title: Characteristic dietary habits associated with high values of estimated 24-hours urinary sodium excretion and sodium-to-potassium ratio assessed by age group among the residents of a rural town in Japan

description: Excess salt intake causes hypertension and cardiovascular disease (CVD). We examined estimated 24-h urinary sodium (Na) excretion and sodium-to-potassium (Na/K) ratio and analyzed the association between estimated 24-h urinary salt excretion (urinary salt excretion) and dietary habits by age group to develop effective public health programs to promote salt reduction. A total of 4,051 subjects aged 30–74 years old received information during periodic health checkups. In the analysis, 1,202 subjects without hypertension whose urine samples and dietary habits were confirmed (29.7%; 483 men and 719 women) were included. The median urinary salt excretion was 9.1 g/day in men and 8.6 g/day in women. Daily intake of soups in men aged &lt;50 years old and daily intake of beans, soups, or pickles in women aged ≥70 years old were associated with high values of urinary salt excretion (<i>p</i> = .03, <i>p</i> &lt; .01, <i>p</i> = .01, and <i>p</i> = .02, respectively). The median urinary Na/K ratio (mEq/mEq) was 4.4 in both men and women. Daily intake of vegetables in men aged &lt;50 years old and more than 3 days/week intake of fruit in women aged 50–59 and 60–69 years old were associated with lower values of urinary Na/K ratio (<i>p</i> = .03, <i>p</i> &lt; .01, and <i>p</i> &lt; .01, respectively). These findings revealed that dietary salt reduction should be promoted according to age group with regard to differences in dietary habits associated with high values of estimated 24-h urinary Na excretion and urinary Na/K ratio.
DOI: 10.6084/m9.figshare.10576637
title: System parameters of case studies.

description: system parameters
DOI: 10.6084/m9.figshare.10582124.v1
title: data for logistic regression analyses (exp 1)

description: data from exp 1 is given in a form ready for logistic regression analyses <br><b>*** important ***</b>the logistic-regression ready data from exp 2 can be generated through the R codes for experiment 2
DOI: 10.6084/m9.figshare.10576637.v2
title: System parameters of case studies.

description: system parameters
DOI: 10.6084/m9.figshare.10576637.v1
title: System parameters of case studies.

description: system parameters
DOI: 10.6084/m9.figshare.10567109
title: CR6 interacting factor 1 deficiency induces premature senescence via SIRT3 inhibition in endothelial cells

description: Raw data for submission to open access journal
DOI: 10.6084/m9.figshare.10567109.v1
title: CR6 interacting factor 1 deficiency induces premature senescence via SIRT3 inhibition in endothelial cells

description: Raw data for submission to open access journal
DOI: 10.6084/m9.figshare.10567082
title: MOESM2 of Development of a high number, high coverage dog rabies vaccination programme in Sri Lanka

description: Additional file 2: Figure S2. Results from the univariable regression analysis. Variables whose P value was under 0.2 were considered for the model and included in the models created mostly by forward selection. The age category was divided into adult (over one year of age) and young (less than one year) for the final model due to low counts of puppy dogs.
DOI: 10.6084/m9.figshare.10567082.v1
title: MOESM2 of Development of a high number, high coverage dog rabies vaccination programme in Sri Lanka

description: Additional file 2: Figure S2. Results from the univariable regression analysis. Variables whose P value was under 0.2 were considered for the model and included in the models created mostly by forward selection. The age category was divided into adult (over one year of age) and young (less than one year) for the final model due to low counts of puppy dogs.
DOI: 10.6084/m9.figshare.10567064
title: MOESM1 of Structural variant calling: the long and the short of it

description: Additional file 1: Table S1.
DOI: 10.6084/m9.figshare.10567064.v1
title: MOESM1 of Structural variant calling: the long and the short of it

description: Additional file 1: Table S1.
DOI: 10.6084/m9.figshare.10566998
title: MOESM8 of Infection and RNA-seq analysis of a zebrafish tlr2 mutant shows a broad function of this toll-like receptor in transcriptional and metabolic control and defense to Mycobacterium marinum infection

description: Additional file 8: Figure S8. Sub-network enrichment analysis. Networks of common targets of the 97 up regulated genes (Fig. 6d) in tlr2+/− (a) and tlr2−/− (b) with Mma20 infection. Red represents up regulation, blue represents down regulation and grey represents genes for which no expression was detected.
DOI: 10.6084/m9.figshare.10566998.v1
title: MOESM8 of Infection and RNA-seq analysis of a zebrafish tlr2 mutant shows a broad function of this toll-like receptor in transcriptional and metabolic control and defense to Mycobacterium marinum infection

description: Additional file 8: Figure S8. Sub-network enrichment analysis. Networks of common targets of the 97 up regulated genes (Fig. 6d) in tlr2+/− (a) and tlr2−/− (b) with Mma20 infection. Red represents up regulation, blue represents down regulation and grey represents genes for which no expression was detected.
DOI: 10.6084/m9.figshare.10566953
title: MOESM16 of Infection and RNA-seq analysis of a zebrafish tlr2 mutant shows a broad function of this toll-like receptor in transcriptional and metabolic control and defense to Mycobacterium marinum infection

description: Additional file 16: Table S5. List of primers.
DOI: 10.6084/m9.figshare.10566944
title: MOESM15 of Infection and RNA-seq analysis of a zebrafish tlr2 mutant shows a broad function of this toll-like receptor in transcriptional and metabolic control and defense to Mycobacterium marinum infection

description: Additional file 15: Table S4. A-H Gene lists of GSEA and SNEA analysis.
DOI: 10.6084/m9.figshare.10566953.v1
title: MOESM16 of Infection and RNA-seq analysis of a zebrafish tlr2 mutant shows a broad function of this toll-like receptor in transcriptional and metabolic control and defense to Mycobacterium marinum infection

description: Additional file 16: Table S5. List of primers.
DOI: 10.6084/m9.figshare.10566938
title: MOESM14 of Infection and RNA-seq analysis of a zebrafish tlr2 mutant shows a broad function of this toll-like receptor in transcriptional and metabolic control and defense to Mycobacterium marinum infection

description: Additional file 14: Table S3. Two categories of genes including the c-Maf transcription factor were significantly affected in the GO category.
DOI: 10.6084/m9.figshare.10566938.v1
title: MOESM14 of Infection and RNA-seq analysis of a zebrafish tlr2 mutant shows a broad function of this toll-like receptor in transcriptional and metabolic control and defense to Mycobacterium marinum infection

description: Additional file 14: Table S3. Two categories of genes including the c-Maf transcription factor were significantly affected in the GO category.
DOI: 10.6084/m9.figshare.10566944.v1
title: MOESM15 of Infection and RNA-seq analysis of a zebrafish tlr2 mutant shows a broad function of this toll-like receptor in transcriptional and metabolic control and defense to Mycobacterium marinum infection

description: Additional file 15: Table S4. A-H Gene lists of GSEA and SNEA analysis.
DOI: 10.6084/m9.figshare.10566926
title: MOESM12 of Infection and RNA-seq analysis of a zebrafish tlr2 mutant shows a broad function of this toll-like receptor in transcriptional and metabolic control and defense to Mycobacterium marinum infection

description: Additional file 12: Table S1. Reads of mpeg1.1 and mpx genes of the tlr2+/− control and the tlr2−/− mutant in RNAseq analysis.
DOI: 10.6084/m9.figshare.10566929
title: MOESM13 of Infection and RNA-seq analysis of a zebrafish tlr2 mutant shows a broad function of this toll-like receptor in transcriptional and metabolic control and defense to Mycobacterium marinum infection

description: Additional file 13: Table S2. GO analysis of genes that have a different basal expression level in the absence of infection in the Tlr2 mutant versus the heterozygote control. Shown is the GO analysis of the group of 878 genes that were different with a FDR P value of 10− 10 indicated in Fig. 2.
DOI: 10.6084/m9.figshare.10566929.v1
title: MOESM13 of Infection and RNA-seq analysis of a zebrafish tlr2 mutant shows a broad function of this toll-like receptor in transcriptional and metabolic control and defense to Mycobacterium marinum infection

description: Additional file 13: Table S2. GO analysis of genes that have a different basal expression level in the absence of infection in the Tlr2 mutant versus the heterozygote control. Shown is the GO analysis of the group of 878 genes that were different with a FDR P value of 10− 10 indicated in Fig. 2.
DOI: 10.6084/m9.figshare.10566926.v1
title: MOESM12 of Infection and RNA-seq analysis of a zebrafish tlr2 mutant shows a broad function of this toll-like receptor in transcriptional and metabolic control and defense to Mycobacterium marinum infection

description: Additional file 12: Table S1. Reads of mpeg1.1 and mpx genes of the tlr2+/− control and the tlr2−/− mutant in RNAseq analysis.
DOI: 10.6084/m9.figshare.10566815
title: MOESM1 of Exome resequencing and GWAS for growth, ecophysiology, and chemical and metabolomic composition of wood of Populus trichocarpa

description: Additional file 1: Table S1. a Number of significant single SNP-markers. b. Proportion of significant SNPs on total analyzed SNPs. Table S2. Number of significant sliding windows. Table S3. Top three significantly associated single SNPs. Table S4. Top three significantly associated SNP-windows.
DOI: 10.6084/m9.figshare.10566815.v1
title: MOESM1 of Exome resequencing and GWAS for growth, ecophysiology, and chemical and metabolomic composition of wood of Populus trichocarpa

description: Additional file 1: Table S1. a Number of significant single SNP-markers. b. Proportion of significant SNPs on total analyzed SNPs. Table S2. Number of significant sliding windows. Table S3. Top three significantly associated single SNPs. Table S4. Top three significantly associated SNP-windows.
DOI: 10.6084/m9.figshare.10566806
title: MOESM1 of Molecular and immune correlates of TIM-3 (HAVCR2) and galectin 9 (LGALS9) mRNA expression and DNA methylation in melanoma

description: Additional file 1. Associations and correlations of TIM-3 and LGALS9 methylation and mRNA expression with clinical-pathological parameters, molecular features and immune cell infiltrates in N = 470 melanoma patients from The Cancer Genome Atlas. Molecular data were obtained from The Cancer Genome Atlas [28]. P-values refer to Kruskal-Wallis (&gt; two group comparisons), Wilcoxon Mann-Whitney U (2 group comparison) tests, and Spearman’s rank correlation (continuous variables), respectively.
DOI: 10.6084/m9.figshare.10566806.v1
title: MOESM1 of Molecular and immune correlates of TIM-3 (HAVCR2) and galectin 9 (LGALS9) mRNA expression and DNA methylation in melanoma

description: Additional file 1. Associations and correlations of TIM-3 and LGALS9 methylation and mRNA expression with clinical-pathological parameters, molecular features and immune cell infiltrates in N = 470 melanoma patients from The Cancer Genome Atlas. Molecular data were obtained from The Cancer Genome Atlas [28]. P-values refer to Kruskal-Wallis (&gt; two group comparisons), Wilcoxon Mann-Whitney U (2 group comparison) tests, and Spearman’s rank correlation (continuous variables), respectively.
DOI: 10.6084/m9.figshare.10566641
title: MOESM1 of Pravastatin induces NO synthesis by enhancing microsomal arginine uptake in healthy and preeclamptic placentas

description: Additional file 1. Detailed clinical data of participants.
DOI: 10.6084/m9.figshare.10566641.v1
title: MOESM1 of Pravastatin induces NO synthesis by enhancing microsomal arginine uptake in healthy and preeclamptic placentas

description: Additional file 1. Detailed clinical data of participants.
DOI: 10.6084/m9.figshare.10566626
title: MOESM1 of Functional connectivity studies in migraine: what have we learned?

description: Additional file 1: Table S2. Schematic overview of regions with an altered functional connectivity to the examined networks throughout 25 studies of interictal migraine compared with healthy volunteers
DOI: 10.6084/m9.figshare.10566626.v1
title: MOESM1 of Functional connectivity studies in migraine: what have we learned?

description: Additional file 1: Table S2. Schematic overview of regions with an altered functional connectivity to the examined networks throughout 25 studies of interictal migraine compared with healthy volunteers
DOI: 10.6084/m9.figshare.10566458
title: Body Mass Data

description: All body mass measurements for the field season in grams and the corresponding date each measurement was taken<br>
DOI: 10.6084/m9.figshare.10566461
title: Survival Data

description: The data used to generate survival information. For each vole, in the column "Last" is the last day (in number of days from the start of the field season) the vole was recorded by RFID antennas or caught in live traps (whichever was later)<br>
DOI: 10.6084/m9.figshare.10566359
title: Data for number of offspring and mates

description: The number of offspring and successful mating partners for each vole.<br>
DOI: 10.6084/m9.figshare.10566458.v1
title: Body Mass Data

description: All body mass measurements for the field season in grams and the corresponding date each measurement was taken<br>
DOI: 10.6084/m9.figshare.10566461.v1
title: Survival Data

description: The data used to generate survival information. For each vole, in the column "Last" is the last day (in number of days from the start of the field season) the vole was recorded by RFID antennas or caught in live traps (whichever was later)<br>
DOI: 10.6084/m9.figshare.10566269
title: Density/Sex Ratio Data

description: Data showing the number of males, females, offspring, and total adult voles caught in live traps during each two week period of data collection for both the high density (HD) and low density (LD) enclosures. This file also has the number of times traps were set during the two week period and the sex ratio, calculated as the proportion of total adult individuals that were male.<br>
DOI: 10.6084/m9.figshare.10566269.v1
title: Density/Sex Ratio Data

description: Data showing the number of males, females, offspring, and total adult voles caught in live traps during each two week period of data collection for both the high density (HD) and low density (LD) enclosures. This file also has the number of times traps were set during the two week period and the sex ratio, calculated as the proportion of total adult individuals that were male.<br>
DOI: 10.6084/m9.figshare.10566359.v1
title: Data for number of offspring and mates

description: The number of offspring and successful mating partners for each vole.<br>
DOI: 10.6084/m9.figshare.10566029
title: Dataset_submitted to JGR-Oceans Deoxygenation and its controls in a semi-enclosed shelf ecosystem, northern Yellow Sea

description: This dataset provides the long-term monitoring data in the northern Yellow Sea (NYS) from 1976 to 2006, including temperature, salinity, dissolved oxygen (DO), apparent oxygen utilization (AOU), DO saturation and nutrients along the section of Chengshanjiao-Dalian. There are four sheets of “Winter”, “Summer”, "Water column in winter" and "Water column in summer" in the Data Table. The “Winter” and “Summer” sheets show the surface and bottom time series data in winter and summer, respectively, while the "Water column in winter" and "Water column in summer" sheets display the climatological values of related parameters for each monitoring site in winter and summer, respectively.
DOI: 10.6084/m9.figshare.10565987
title: SourceMemory_Age_verbal responses.xlsx

description: This study looked at eye movements in relation to source memory in older adults. Participants first studied images of common objects appearing in different quadrants of a screen. After a delay, they were shown cues one at a time presented in all four quadrants. Participants stated whether or not the cue had been seen before and in which location. Participants also rated level of confidence in their responses. In trials where participants either claimed they have not seen a previously presented cue or placed it in an incorrect location, they looked significantly more at the correct quadrant. The proportion of time looking at the correct quadrants during incorrect responses was not related to confidence ratings. These results suggest that eye gaze during the memory task does not reflect memory retrieval below the threshold of verbal report. They instead point to an implicit form of source memory in humans that is accessible to eye movements but not to verbal responses.The data consist of: E-Prime output participant files recording the behavioral and eye tracking data, and a file with the participants location responses which were manually recorded.
DOI: 10.17608/k6.auckland.10565963
title: Abel Tasman and Marlborough Mouse microsatellite data

description: Microsatellite data (ID, Location, collection year and called alleles) accompanying the paper:<br><br><b>Island invasion and reinvasion: Informing invasive species management with genetic measures of connectivity</b><br>by Florian Pichlmueller, Elaine C. Murphy, Jamie B. MacKay, John Henderson, Rachel M. Fewster, James C. Russell<br><br>
DOI: 10.6084/m9.figshare.10565969
title: Data for vegetation and soil parameters .xlsx

description: The aboveground biomass, vegetation cover, LAI, carbon content of vegetation and soil organ carbon on four levels of degraded alpine wetland meadows.