cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.6503036.v1
title: Does fertility in Brazil and Argentina converge? A focus on inequalities

description: Abstract The idea of trend in fertility levels towards convergence in Latin America and the Caribbean is widely accepted, both in academic studies and in the underlying assumptions of the population projections in the region. However, little is known about the demographic convergence processes when fertility is decomposed according to variables of social differentiation. The aim of this article is to compare the convergence hypothesis in Argentina and Brazil from 1970 to 2010 through the analysis of the evolution of the Total Fertility Rate by statistical regions, educational levels and socio-occupational categories. Data come from national population censuses and variables were harmonized to allow comparisons between both countries. A variation of the Brass P/F ratio method and the Gompertz relational model was used to estimate fertility levels and measures of convergence was calculated to assess the hypothesis of convergence according to the categories of analysis. The results show evidence of convergence in fertility during the period of study, especially in Brazil, although some cycles of divergence and marked differences between the two countries were observed, particularly those arising from the position in the occupational structure.
DOI: 10.6084/m9.figshare.6503033
title: Genetic diversity between papaya lines and their correlation with heterosis in hybrids for disease resistance and morpho-agronomic traits

description: ABSTRACT This study aimed to verify if the genetic divergence between papaya lines, obtained by means of molecular markers, is correlated with heterosis in the hybrids for characteristics related to production, fruit quality and disease resistance. Eight parents and 56 hybrids obtained from diallel crosses were evaluated in randomized blocks, with four replicates. The number of commercial fruits (NCF), the average fruit weight (AFW), the productivity (PROD), the fruit firmness (FIRM) and the total soluble solids (TSS) were evaluated, as well as the severity of black spot on leaves (BSS) and fruits (BSSFr), phoma spot (PSS) and powdery mildew on leaves (PMS). Correlations were estimated between genetic divergence, obtained based on SSR, and heterosis, estimated for each characteristic in four possibilities of crossings within the diallel: i) all crossings; ii) between parents of the ‘Solo’ group; iii) between parents of the ‘Formosa’ group; and iv) between parents of ‘Solo’ with ‘Formosa’ group and ‘Formosa’ with ‘Solo’ group. Results indicate the possibility of exploring heterosis both in crossings between groups and in crossings within groups. The low magnitude of the estimates of correlation between heterosis and morphological characteristics of the hybrids with genetic distance obtained by SSR in the parents indicates that the behavior of hybrids cannot be inferred based on the genetic divergence between parents.
DOI: 10.6084/m9.figshare.6503033.v1
title: Genetic diversity between papaya lines and their correlation with heterosis in hybrids for disease resistance and morpho-agronomic traits

description: ABSTRACT This study aimed to verify if the genetic divergence between papaya lines, obtained by means of molecular markers, is correlated with heterosis in the hybrids for characteristics related to production, fruit quality and disease resistance. Eight parents and 56 hybrids obtained from diallel crosses were evaluated in randomized blocks, with four replicates. The number of commercial fruits (NCF), the average fruit weight (AFW), the productivity (PROD), the fruit firmness (FIRM) and the total soluble solids (TSS) were evaluated, as well as the severity of black spot on leaves (BSS) and fruits (BSSFr), phoma spot (PSS) and powdery mildew on leaves (PMS). Correlations were estimated between genetic divergence, obtained based on SSR, and heterosis, estimated for each characteristic in four possibilities of crossings within the diallel: i) all crossings; ii) between parents of the ‘Solo’ group; iii) between parents of the ‘Formosa’ group; and iv) between parents of ‘Solo’ with ‘Formosa’ group and ‘Formosa’ with ‘Solo’ group. Results indicate the possibility of exploring heterosis both in crossings between groups and in crossings within groups. The low magnitude of the estimates of correlation between heterosis and morphological characteristics of the hybrids with genetic distance obtained by SSR in the parents indicates that the behavior of hybrids cannot be inferred based on the genetic divergence between parents.
DOI: 10.6084/m9.figshare.6503030
title: AGREEMENT IN DIAGNOSIS OF KNEE INJURIES BY ORTHOPEDISTS WITH CLINICAL EXPERIENCE IN KNEE TREATMENT

description: ABSTRACT Objective: To analyze the level of agreement in diagnosing knee injury among orthopedists with clinical experience in knee treatment. Method: An online questionnaire was used to analyze the ability of orthopedic knee surgeons to diagnose intra-articular knee injuries using MRI, the importance given to this test in their clinical practice, and the agreement between these diagnoses and the radiology report. Results: The study participants considered MRI an important tool for clarifying inconclusive diagnoses and surgical planning. The level of agreement between the surgeons and the radiologist was considered to be very slight for posterior cruciate ligament injuries, collateral ligament injuries, and chondral injuries, and was considered slight for anterior cruciate ligament and meniscus injuries. Conclusion: A diagnosis of intra-articular knee injury must be based on the patient history, physical examination, and radiological imaging (MRI) in order to provide a complete approach to the patient. Level of Evidence III; Clinical study.
DOI: 10.6084/m9.figshare.6503030.v1
title: AGREEMENT IN DIAGNOSIS OF KNEE INJURIES BY ORTHOPEDISTS WITH CLINICAL EXPERIENCE IN KNEE TREATMENT

description: ABSTRACT Objective: To analyze the level of agreement in diagnosing knee injury among orthopedists with clinical experience in knee treatment. Method: An online questionnaire was used to analyze the ability of orthopedic knee surgeons to diagnose intra-articular knee injuries using MRI, the importance given to this test in their clinical practice, and the agreement between these diagnoses and the radiology report. Results: The study participants considered MRI an important tool for clarifying inconclusive diagnoses and surgical planning. The level of agreement between the surgeons and the radiologist was considered to be very slight for posterior cruciate ligament injuries, collateral ligament injuries, and chondral injuries, and was considered slight for anterior cruciate ligament and meniscus injuries. Conclusion: A diagnosis of intra-articular knee injury must be based on the patient history, physical examination, and radiological imaging (MRI) in order to provide a complete approach to the patient. Level of Evidence III; Clinical study.
DOI: 10.6084/m9.figshare.6503027
title: Suicidal ideation, anxiety, and depression in patients with multiple sclerosis

description: ABSTRACT Psychiatric disorders frequently occur in patients with multiple sclerosis (MS); however, limited reports are available on these comorbidities. We aimed to investigate the relationships among MS, anxiety, depression, and suicidal ideation. Methods: One hundred and thirty two patients with relapsing-remitting MS were evaluated using the Expanded Disability Status Scale, Beck Depression Inventory-II (BDI-II), Beck Scale for Suicide Ideation (BSI), and Hospital Anxiety and Depression Scale. Results: A hierarchical regression analysis was performed to evaluate the variables. The regression equation significantly predicted the BSI score (R2 = 0.306; adjusted R2 = 0.273; F (9, 125) = 9.18; p &lt; 0.0005), and the BDI-II score was the only variable that contributed significantly to this model (p &lt; 0.0005). Conclusions: A high prevalence of depression and anxiety, and a higher rate of suicidal ideation were identified in MS patients compared to the general population. The presence of depressive symptoms appeared to have a direct influence on the risk of suicide.
DOI: 10.6084/m9.figshare.6503027.v1
title: Suicidal ideation, anxiety, and depression in patients with multiple sclerosis

description: ABSTRACT Psychiatric disorders frequently occur in patients with multiple sclerosis (MS); however, limited reports are available on these comorbidities. We aimed to investigate the relationships among MS, anxiety, depression, and suicidal ideation. Methods: One hundred and thirty two patients with relapsing-remitting MS were evaluated using the Expanded Disability Status Scale, Beck Depression Inventory-II (BDI-II), Beck Scale for Suicide Ideation (BSI), and Hospital Anxiety and Depression Scale. Results: A hierarchical regression analysis was performed to evaluate the variables. The regression equation significantly predicted the BSI score (R2 = 0.306; adjusted R2 = 0.273; F (9, 125) = 9.18; p &lt; 0.0005), and the BDI-II score was the only variable that contributed significantly to this model (p &lt; 0.0005). Conclusions: A high prevalence of depression and anxiety, and a higher rate of suicidal ideation were identified in MS patients compared to the general population. The presence of depressive symptoms appeared to have a direct influence on the risk of suicide.
DOI: 10.6084/m9.figshare.6503009
title: A review of 50 cases of bath-related headache: clinical features and possible diagnostic criteria

description: ABSTRACT Objective: To describe clinical features and possible diagnostic criteria of the 50 bath-related headache (BRH) cases that have been published in the literature to date. Methods: Based on a literature search in the major medical databases, we analyzed all case reports or case series on BRH that were published between 2000 and 2017. Results: We describe 48 women and two men diagnosed with BRH. Of these 50 patients, 90% were from Asian countries. The average age was 49.3 years. There was an association of BRH with migraine (28%), tension-type headache (12%) and cold stimulus headache (4%). Headache was bilaterally localized, had an explosive or pulsating quality and a severe intensity. The pain lasted from five minutes to four days. Associated manifestations were nausea, vomiting, photophobia or phonophobia. There was a good therapeutic response with nimodipine and when avoiding a hot bath. Conclusions: Bath-related headache is a benign headache that is not associated with a structural lesion.
DOI: 10.6084/m9.figshare.6503009.v1
title: A review of 50 cases of bath-related headache: clinical features and possible diagnostic criteria

description: ABSTRACT Objective: To describe clinical features and possible diagnostic criteria of the 50 bath-related headache (BRH) cases that have been published in the literature to date. Methods: Based on a literature search in the major medical databases, we analyzed all case reports or case series on BRH that were published between 2000 and 2017. Results: We describe 48 women and two men diagnosed with BRH. Of these 50 patients, 90% were from Asian countries. The average age was 49.3 years. There was an association of BRH with migraine (28%), tension-type headache (12%) and cold stimulus headache (4%). Headache was bilaterally localized, had an explosive or pulsating quality and a severe intensity. The pain lasted from five minutes to four days. Associated manifestations were nausea, vomiting, photophobia or phonophobia. There was a good therapeutic response with nimodipine and when avoiding a hot bath. Conclusions: Bath-related headache is a benign headache that is not associated with a structural lesion.
DOI: 10.6084/m9.figshare.6503006
title: Validated registry of pre-dialysis chronic kidney disease: description of a large cohort

description: ABSTRACT Introduction: Chronic diseases account for the majority of deaths in Brazil. These include hypertension (SAH) and diabetes mellitus (DM), which are the main causes of chronic kidney disease (CKD). Objective: This study aimed to validate the data of an electronic health record and to point out characteristics of the profile of these users in relation to clinical quality indicators for a pre-dialytic CKD. Methods: Retrospective cohort, August/2010 to December/2014. Included users &gt; 18 years, with at least two queries. Variables analyzed: sociodemographic, underlying disease, main medications and main clinical indicators of control. A descriptive analysis was performed and the percentage of users was evaluated in the goals at admission and at the end of the study. Results: Exported, converted and validated data of 1,977 users with average follow-up time of 21 months. Of these, 51.4% were men, 58% were &gt; 64 years of age and 81.6% were overweight. The main medications in use were diuretics (82.9%), BRAT (62%), Statin (60.7%) and ACE inhibitors (49.9%). The percentage of users with a decline in the glomerular filtration rate was 33.7%. Regarding glycated hemoglobin, users with CKD and DM, 36% were within the initial goal and 52.1% of the final. Blood pressure was at the target for admission at 34.3% and 49.8% at the end of follow-up. Conclusion: Validated data are of vital importance for health managers to monitor users. The population of this study is predominantly elderly, obese, requiring multi-professional care to slow the progression of the disease and decrease morbidity and mortality.
DOI: 10.6084/m9.figshare.6503006.v1
title: Validated registry of pre-dialysis chronic kidney disease: description of a large cohort

description: ABSTRACT Introduction: Chronic diseases account for the majority of deaths in Brazil. These include hypertension (SAH) and diabetes mellitus (DM), which are the main causes of chronic kidney disease (CKD). Objective: This study aimed to validate the data of an electronic health record and to point out characteristics of the profile of these users in relation to clinical quality indicators for a pre-dialytic CKD. Methods: Retrospective cohort, August/2010 to December/2014. Included users &gt; 18 years, with at least two queries. Variables analyzed: sociodemographic, underlying disease, main medications and main clinical indicators of control. A descriptive analysis was performed and the percentage of users was evaluated in the goals at admission and at the end of the study. Results: Exported, converted and validated data of 1,977 users with average follow-up time of 21 months. Of these, 51.4% were men, 58% were &gt; 64 years of age and 81.6% were overweight. The main medications in use were diuretics (82.9%), BRAT (62%), Statin (60.7%) and ACE inhibitors (49.9%). The percentage of users with a decline in the glomerular filtration rate was 33.7%. Regarding glycated hemoglobin, users with CKD and DM, 36% were within the initial goal and 52.1% of the final. Blood pressure was at the target for admission at 34.3% and 49.8% at the end of follow-up. Conclusion: Validated data are of vital importance for health managers to monitor users. The population of this study is predominantly elderly, obese, requiring multi-professional care to slow the progression of the disease and decrease morbidity and mortality.
DOI: 10.6084/m9.figshare.6503003
title: Protein-energy adequacy and nutritional evolution of preterm infants in neonatal intensive care unit

description: ABSTRACT Objective To evaluate the prescription of protein-calorie nutrition and its adequacy to the requirements of preterm newborns. Methods Prospective study with 30 preterm infants from a neonate intensive unit care. Anthropometric and nutritional therapy data were collected daily. Nutritional demands were defined according to the national guidelines. Protein-calorie nutritional support was considered adequate when it reached 70% of the calculated demand. The evolution of nutritional status was evaluated according to the growth curves of preterm infants. Statistical analyses were performed with the Statistical Package for Social Sciences 20.0, at a 5% significance level. Results The means of demand, prescription and infusion significantly differed from each other. The values of calories and proteins prescribed and infused were inadequate according to the calculated ones. There was no significant difference between the volume of prescribed and administered nutrition (p&gt;0.05). At birth, 30% of the children were small, 66.7% were adequate, and 3.3% were large for gestational age. At discharge, the percentages were 33.3%; 63.3%; 3.3%, respectively. The values at birth significantly differed from those at discharge (p&lt;0.01). Conclusion In the Unit of Neonatal Care studied, inadequate nutrient prescription and support is a factor that can compromise the nutritional status of the newborns at hospital discharge.
DOI: 10.6084/m9.figshare.6503003.v1
title: Protein-energy adequacy and nutritional evolution of preterm infants in neonatal intensive care unit

description: ABSTRACT Objective To evaluate the prescription of protein-calorie nutrition and its adequacy to the requirements of preterm newborns. Methods Prospective study with 30 preterm infants from a neonate intensive unit care. Anthropometric and nutritional therapy data were collected daily. Nutritional demands were defined according to the national guidelines. Protein-calorie nutritional support was considered adequate when it reached 70% of the calculated demand. The evolution of nutritional status was evaluated according to the growth curves of preterm infants. Statistical analyses were performed with the Statistical Package for Social Sciences 20.0, at a 5% significance level. Results The means of demand, prescription and infusion significantly differed from each other. The values of calories and proteins prescribed and infused were inadequate according to the calculated ones. There was no significant difference between the volume of prescribed and administered nutrition (p&gt;0.05). At birth, 30% of the children were small, 66.7% were adequate, and 3.3% were large for gestational age. At discharge, the percentages were 33.3%; 63.3%; 3.3%, respectively. The values at birth significantly differed from those at discharge (p&lt;0.01). Conclusion In the Unit of Neonatal Care studied, inadequate nutrient prescription and support is a factor that can compromise the nutritional status of the newborns at hospital discharge.
DOI: 10.6084/m9.figshare.6503000
title: Factors associated with body image dissatisfaction of the elderly who practice weight training

description: Abstract Introduction: The body image is a multidimensional construct of the internal and external representations of the corporal structures added to the physical appearance, which can be influenced by aging. The weight training can be an important exercise to help elderly to face all the changes arising from aging, being one of them the dissatisfaction with body image. Objective: This study aims at identifying the factors associated with body image dissatisfaction of the elderly who practice weight training. Methods: This is an observational cross-sectional study. The sample, chosen by convenience and intentionally, embraced 174 male and female elderly subjects who practice weight training at one of the 15 fitness centers drawn for the research that offered this modality of physical exercise in Maringá city, state of Paraná, Brazil. A questionnaire with sociodemographic and health profile questions was used, as well as the BSQ to assess body dissatisfaction. Data analysis was carried out by using a descriptive inferential statistical approach with the Chi-squared test, Fischer's exact test, and binary logistic regression, adopting a significance when p &lt; 0.05. Results: The majority of the elderly showed no body dissatisfaction (82.2%). There was a significant association among the absence of body dissatisfaction and the following items: retirement (p = 0.031), current study (p = 0.035), self perception of health (p = 0.016), body self perception (p = 0.001), and practice time (p = 0.027). Conclusion: Based on the results obtained, it can be concluded that the sociodemographic factors are intervenient when considering body dissatisfaction of the elderly people who practice weight training.
DOI: 10.6084/m9.figshare.6502997
title: Role of non-coding RNAs in non-aging-related neurological disorders

description: Protein coding sequences represent only 2% of the human genome. Recent advances have demonstrated that a significant portion of the genome is actively transcribed as non-coding RNA molecules. These non-coding RNAs are emerging as key players in the regulation of biological processes, and act as "fine-tuners" of gene expression. Neurological disorders are caused by a wide range of genetic mutations, epigenetic and environmental factors, and the exact pathophysiology of many of these conditions is still unknown. It is currently recognized that dysregulations in the expression of non-coding RNAs are present in many neurological disorders and may be relevant in the mechanisms leading to disease. In addition, circulating non-coding RNAs are emerging as potential biomarkers with great potential impact in clinical practice. In this review, we discuss mainly the role of microRNAs and long non-coding RNAs in several neurological disorders, such as epilepsy, Huntington disease, fragile X-associated ataxia, spinocerebellar ataxias, amyotrophic lateral sclerosis (ALS), and pain. In addition, we give information about the conditions where microRNAs have demonstrated to be potential biomarkers such as in epilepsy, pain, and ALS.
DOI: 10.6084/m9.figshare.6503000.v1
title: Factors associated with body image dissatisfaction of the elderly who practice weight training

description: Abstract Introduction: The body image is a multidimensional construct of the internal and external representations of the corporal structures added to the physical appearance, which can be influenced by aging. The weight training can be an important exercise to help elderly to face all the changes arising from aging, being one of them the dissatisfaction with body image. Objective: This study aims at identifying the factors associated with body image dissatisfaction of the elderly who practice weight training. Methods: This is an observational cross-sectional study. The sample, chosen by convenience and intentionally, embraced 174 male and female elderly subjects who practice weight training at one of the 15 fitness centers drawn for the research that offered this modality of physical exercise in Maringá city, state of Paraná, Brazil. A questionnaire with sociodemographic and health profile questions was used, as well as the BSQ to assess body dissatisfaction. Data analysis was carried out by using a descriptive inferential statistical approach with the Chi-squared test, Fischer's exact test, and binary logistic regression, adopting a significance when p &lt; 0.05. Results: The majority of the elderly showed no body dissatisfaction (82.2%). There was a significant association among the absence of body dissatisfaction and the following items: retirement (p = 0.031), current study (p = 0.035), self perception of health (p = 0.016), body self perception (p = 0.001), and practice time (p = 0.027). Conclusion: Based on the results obtained, it can be concluded that the sociodemographic factors are intervenient when considering body dissatisfaction of the elderly people who practice weight training.