cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.23118164.v1
title: Network Intrusion Detection Datasets

description: With the continuous expansion of data exchange, the threat of cybercrime and network invasions is also on the rise. This project aims to address these concerns by investigating an innovative approach: an Attentive Transformer Deep Learning Algorithm for Intrusion Detection of IoT Systems using Automatic Xplainable Feature Selection. The primary focus of this project is to develop an effective Intrusion Detection System (IDS) using the aforementioned algorithm. To accomplish this, carefully curated datasets have been utilized, which have been created through a meticulous process involving data extraction from the University of New Brunswick repository. This repository houses the datasets used in this research and can be accessed publically in order to replicate the findings of this research.
DOI: 10.6084/m9.figshare.14154941.v1
title: Interview Analysis

description: Interview analysis from Pediatric Discharge and Follow-up Care Study
DOI: 10.15468/dl.ds2pkh
title: Occurrence Download

description: A dataset containing 10 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Australia",
 "DatasetKey is NSW BioNet Atlas",
 "Geometry POLYGON((151.59493 -33.18142,151.59077 -33.18275,151.59121 -33.1843,151.59125 -33.18934,151.59332 -33.19371,151.59742 -33.19412,151.60024 -33.19529,151.60525 -33.19503,151.60904 -33.19229,151.61017 -33.18832,151.60945 -33.18444,151.60738 -33.18193,151.60579 -33.17902,151.60253 -33.17835,151.59924 -33.17912,151.59493 -33.18142))",
 "IucnRedListCategory is one of (EX, EW, CR, EN, VU)",
 "OccurrenceStatus is Present"
 ]
}

 The dataset includes 10 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0009502-250426092105405/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.3406282.v1
title: TAT.ARC protein transduction or RNA interference with ARC impact on survival of primary cortical neurons subjected to 150 min oxygen-glucose deprivation (OGD): Lactate dehydrogenase activity was measured as a marker of cell membrane integrity loss and neuronal cell death 24 h afterwards.

description: Primary neuronal cultures were transduced with lentiviral particles for knockdown of apoptosis repressor with CARD domain (ARC) or non-targeting control or treated with TAT proteins for ARC or beta Galaktosidase before 150 min of oxygen glucose deprivation (OGD). Cell death was monitored by the release of lactate dehydrogenase (LDH) in the supernatant medium.
DOI: 10.6084/m9.figshare.23541447.v2
title: Supplementary Material for: Patient Preferences: Results of a German Adaptive Choice-Based Conjoint Analysis (Market Research Study Sponsored by Eli Lilly and Company) in Patients on Palliative Treatment for Advanced Breast Cancer

description: <b><i>Introduction:</i></b> Integration of patient preferences into shared decision making improves disease-related outcomes, but such data from patients with advanced breast cancer (aBC) are limited. The objective of this study was to demonstrate the relative importance of overall survival (OS) and progression-free survival (PFS) in relation to quality of life (QoL) and therapy-associated side effects from the perspective of patients with aBC. <b><i>Methods:</i></b> Postmenopausal patients with hormone receptor-positive, human epidermal growth factor receptor 2-negative aBC receiving first- or second-line treatment were recruited throughout Germany. Patient-relevant attributes for aBC therapy assessment were collected using a stepwise multimodal approach. A conjoint matrix was developed, resulting in 2 attributes for therapy goals (OS and PFS), 4 for QoL, and 6 for side effects. An online quantitative survey was then performed using adaptive choice-based conjoint (ACBC) methodology. <b><i>Results:</i></b> The quantitative survey included 104 patients: 67 (64.4%) receiving first-line treatment and 37 (35.6%) receiving second-line treatment. The QoL attribute “physical agility and mobility” received the highest utility score (19.4 of 100%), reflecting the greatest importance to patients, followed by treatment goals (OS [15.2%] and PFS [14.4%]). Therapy-related side effects were less important, with nausea/vomiting being the most important (9.3%), followed by infection (6.4%) and hair loss (5.0%). The McFadden pseudo <i>R</i><sup>2</sup> (0.805), the root likelihood (0.864), and the χ<sup>2</sup> test (2,809.041; <i>p</i> &lt; 0.0001) indicated a very good fit of the statistical model. <b><i>Conclusion:</i></b> Using ACBC analysis, it appears that QoL, OS, and PFS are most important to postmenopausal patients with aBC in relation to cancer treatment. Side effects seem to be less important if OS or PFS are prolonged and the QoL is maintained. Thus, QoL, OS, and PFS should be considered equally when making treatment decisions in aBC.
DOI: 10.6084/m9.figshare.25441186.v1
title: Supplementary Material for: Alcohol use and mental health: how genetic information can help unravel their relationship

description: Background: Traditional epidemiological evidence suggests various associations exist between alcohol and mental/cognitive health outcomes. However, whether these reflect causal relationships remains unclear. Mendelian Randomization (MR) – a kind of instrumental variables analysis using genetic variants to proxy for an exposure of interest – has the potential to improve causal inference from observational data.
Summary: In the first part of this review, the challenges of causal inference in the field are discussed, and a theoretical and practical introduction to the technique of MR is given. Next, we report on literature searches performed to update a previous systematic review of MR studies evaluating alcohol–mental health relationships. Twelve relevant studies were identified and considered in the context of the 22 studies included in the previous review. While the reviewed MR literature suggests possible causal relationships/a lack thereof, for the most part, the nature of causal relationships between alcohol and mental health remains unclear. 
Key messages: MR is beginning to yield valuable insights into the causal effects of (problematic) alcohol consumption on mental and cognitive health outcomes. Future studies must be mindful of the technique’s underlying assumptions and should allow for potential non-linearity in relationships. Triangulating across sensitivity methods within MR studies, as well as between MR studies and other methods for enhanced causal inference, will be crucial.
DOI: 10.6084/m9.figshare.26818192.v1
title: Supplementary Material for: ASSOCIATION OF INSULIN RECEPTOR SUBSTRATE 1 (IRS 1) EXPRESSION IN THE PROGNOSIS OF HEAD AND NECK SQUAMOUS CELL CARCINOMA - A SYSTEMATIC REVIEW AND META ANALYSIS

description: INTRODUCTION: Head and neck squamous cell carcinoma (HNSCC) is the most common mucosal neoplasm that affects the head and neck region. It is the 6th most common cancer globally, most commonly seen in South Asian countries. Insulin receptor substrate 1 (IRS-1) like Insulin Receptor (IR) is an adaptor protein that integrates multiple transmembrane signals from growth factors and hormones, to regulate cell growth, survival, differentiation, and metabolism. Evidence suggests that IRS 1 plays a vital role in cancer progression and nodal metastasis. The aim is to assess the prognostic implications of the insulin receptor substrate 1 expression in head and neck squamous cell carcinoma from evidence-based results.

METHODS: A systematic literature search was done to identify articles describing Insulin receptor substrate 1 (IRS 1) and head and neck squamous cell carcinoma carried out for Pubmed, Cochrane, and Google Scholar, using MeSH terms. 

RESULTS: A total of 486 cases of HNSCC were included in this systematic review. Out of 3 studies, increased/high expression of IRS 1 was 67%. 64% of the cases in Stage I and Stage II (TNM staging) showed higher expression of IRS 1, whereas 70% of the Stage III and Stage IV cases showed upregulation of IRS 1. IRS 1 was equally upregulated in cases with lymph node metastasis as well as in cases without any lymph node metastasis. 74% of the patients that showed high expression of IRS 1 showed high mortality during the follow-up period of 13 months. 

CONCLUSION: This review concluded that elevated levels of IRS 1 expression were associated with poor prognosis and increased lymph node metastasis
DOI: 10.6084/m9.figshare.3561387.v1
title: Supplement 1. R and WinBUGS code to facilitate running of the covariate state-space model.

description: File List argos.csv (MD5: 231845256e0e3e2780b89b1979b11593) dive.csv (MD5: 0637c54ff8df8166d7f07b80295eaa5a) example.R (MD5: )5c05f59f227390015949a4789d2feef9 dat4bugsCOV.R (MD5: e1648cc3144721f82d351922cd28f7e5) ssmMeta.R (MD5: 63baa0688eb6061afb2f8d7a80a6d2f4) DCRWSmeta_cov1oneway.txt (MD5: 4d1eadc5bc3c88f9d3ac1534c71ab5ba) Description Supplement contains sample data, functions and scripts to prepare the data and fit the covariate state-space model presented in this paper. Two raw data files contain samples of Argos location data (argos.csv) and individual dive data (dive.csv) for a subset of Southern elephant seals tagged with CTD-SRDLs at Davis Station, Antarctica in 2011 under the Australian Integrated Marine Observing System. Following the worked example given in the example.R file should enable readers to run the covariate state-space model and/or fit their own Argos and dive data using the R and WinBUGS codes provided (dat4bugsCOV.R, ssmMeta.R, and DCRWSmeta_cov1oneway.txt). The argos.csv file is a comma-separated file containing the Southern elephant seal raw Argos tracking data. Column definitions "id" - is a unique identifier for the seal from which the tracking data set came. "time" - is the GMT date-time of each observation with the following format: "2001-11-13 07:59:59". "lc" is the Argos location quality class of each observation. Values in ascending order of quality are: "Z", "B", "A", "0", "1", "2", "3". "lon" is the observed longitude in decimal degrees. "lat" is the observed latitude in decimal degress. The dive.csv file is a comma-separated file containing the Southern elephant seal individual dive data. Column definitions "id" - is a unique identifier for the seal from which the dive dataset came (same as for the argos.csv file). "time" - is the GMT date-time of each observation with the following format: "2001-11-13 07:59:59". "MAX_DEP" – the dive covariate used here is the logarithm of the maximum depth in meters recorded for the dive. The reader may use any dive covariate, raw or pre-processed (with any name), here. example.R contains R code for the worked Southern elephant seal example showing model implementation. dat4bugsCOV.R is an R function which prepares and writes input data for WinBUGS model. ssmMeta.R is an R function which fits covariate state-space model to Argos tracking data. DCRWSmeta_cov1oneway.txt contains WinBUGS code for the covariate state-space model.
DOI: 10.6084/m9.figshare.20217581.v2
title: Spatiotemporal Flow L-function

description: This zip contains the code and data used in the simulation experiment and case study mentioned in the paper " Spatiotemporal Flow L-function: a new method for identifying spatiotemporal clusters in geogrphical flow data".
DOI: 10.6084/m9.figshare.27860220.v1
title: "Soil organic carbon increases with decreasing microbial carbon use efficiency during vegetation restoration," GCB-Supplementary Dataset S1.

description: The dataset of the papre "Soil organic carbon increases with decreasing microbial carbon use efficiency during vegetation restoration"
DOI: 10.6084/m9.figshare.19212396.v1
title: Supplementary Table2.pdf

description: Data of non-pollen and pollen in Nile Delta
DOI: 10.6084/m9.figshare.24434446.v1
title: Figure.rar

description: vortex generator
DOI: 10.6084/m9.figshare.5683945.v1
title: Supplementary Material for: The Protective Effects of Κ-Opioid Receptor Stimulation in Hypoxic Pulmonary Hypertension Involve Inhibition of Autophagy Through the AMPK-MTOR Pathway

description: <b><i>Background/Aims:</i></b> In a previous study, we showed that κ-opioid receptor stimulation with the selective agonist U50,488H ameliorated hypoxic pulmonary hypertension (HPH). However, the roles that pulmonary arterial smooth muscle cell (PASMC) proliferation, apoptosis, and autophagy play in κ-opioid receptor-mediated protection against HPH are still unknown. The goal of the present study was to investigate the role of autophagy in U50,488H-induced HPH protection and the underlying mechanisms. <b><i>Methods:</i></b> Rats were exposed to 10% oxygen for three weeks to induce HPH. After hypoxia, the mean pulmonary arterial pressure (mPAP) and the right ventricular pressure (RVP) were measured. Cell viability was monitored using the Cell Counting Kit-8 (CCK-8) assay. Cell apoptosis was detected by flow cytometry and Western blot. Autophagy was assessed by means of the mRFP-GFP-LC3 adenovirus transfection assay and by Western blot. <b><i>Results:</i></b> Inhibition of autophagy by the administration of chloroquine prevented the development of HPH in the rat model, as evidenced by significantly reduced mPAP and RVP, as well as decreased autophagy. U50,488H mimicked the effects of chloroquine, and the effects of U50,488H were blocked by nor-BNI, a selective κ-opioid receptor antagonist. <i>In vitro</i> experiments showed that the inhibition of autophagy by chloroquine was associated with decreased proliferation and increased apoptosis of PASMCs. Under hypoxia, U50,488H also significantly inhibited autophagy, reduced proliferation and increased apoptosis of PASMCs. These effects of U50,488H were blocked by nor-BNI. Moreover, exposure to hypoxic conditions significantly increased AMPK phosphorylation and reduced mTOR phosphorylation, and these effects were abrogated by U50,488H. The effects of U50,488H on PASMC autophagy were inhibited by AICAR, a selective AMPK agonist, or by rapamycin, a selective mTOR inhibitor. <b><i>Conclusion:</i></b> Our data provide evidence for the first time that κ-opioid receptor stimulation protects against HPH by inhibiting PASMCs autophagy via the AMPK-mTOR pathway.
DOI: 10.5525/gla.researchdata.1933
title: PhD Thesis: The Genetic and Cellular Basis of Viviparity
DOI: 10.6084/m9.figshare.14375033.v1
title: Supplementary Material for: Pharmacological Treatment of Osteoporosis in Elderly People: A Systematic Review and Meta-Analysis

description: <b><i>Background:</i></b> The evidence supporting the use of antiresorptive and anabolic agents for fracture prevention in elderly patients is still inconclusive. Whether it is too late to alter the course of the disease in this age-group has remained uncertain. <b><i>Objectives:</i></b> The objective of this study was to determine the efficacy and safety of antiresorptive and anabolic agents in elderly patients. <b><i>Methods:</i></b> PubMed, Web of Science, MEDLINE, and the Cochrane Central Register of Controlled Trials were searched for randomized controlled trials (RCTs) and post hoc analyses of RCTs reporting efficacy outcomes or adverse events of antiresorptive and anabolic agents in elderly patients. Statistical heterogeneity was assessed with the Cochran <i>Q</i> χ<sup>2</sup> test and <i>I</i><sup>2</sup> statistic. All results were expressed as relative risk (RR) with 95% confidence intervals (CIs). <b><i>Results:</i></b> The meta-analysis included 1 RCT and 11 post hoc analyses of data from 10 double-blind placebo-controlled RCTs. Antiresorptive therapy significantly reduced the pooled incidence of vertebral fractures (RR = 0.43; 95% CI = 0.35–0.53; and <i>p</i> &lt; 0.001). It was also associated with lower risk of nonvertebral and hip fractures (RR = 0.84; 95% CI = 0.74–0.96; and <i>p</i> = 0.009 and RR = 0.75; 95% CI = 0.58–0.97; and <i>p</i> = 0.028, respectively). For any adverse events, no difference was observed between antiresorptive agents and placebo groups (RR = 1.01; 95% CI = 1.00–1.02; and <i>p</i> = 0.23). <b><i>Conclusions:</i></b> Both antiresorptive and anabolic agents represented potentially important osteoporosis treatments, showing significant effects on reducing vertebral, nonvertebral, or hip fracture risk, and were well-tolerated by elderly patients. Even in the elderly, maybe it is not too late to alter the course of the disease.
DOI: 10.6084/m9.figshare.16366287.v1
title: DCP Survey Questions

description: Survey Questions
DOI: 10.6084/m9.figshare.24849231.v1
title: Screening Bifidobacterium with Antioxidant Properties from the Initial Intestinal Flora of Neonates-supplementary information.xlsx

description: Screening Bifidobacterium with Antioxidant Properties from the Initial Intestinal Flora of Neonates
DOI: 10.6084/m9.figshare.28234802.v1
title: Dataset for Advancing financial technology through QRIS in Indonesia and Malaysia

description: this is Dataset
DOI: 10.6084/m9.figshare.c.3858004_d2.v1
title: Additional file 2: of Examining database persistence of ISO/EN 13606 standardized electronic health record extracts: relational vs. NoSQL approaches

description: Java program. Program written in Java performing the six queries on the MongoDB database, using the MongoDB query language, and further processing the JSON result in order to produce relational table-like results. (JAVA 32.6 kb)
DOI: 10.6084/m9.figshare.12348218.v1
title: Comparison of article count and fractional count of publications of leading Russian organizations in 2018

description: This is an appednix to the article that introduces the concept of a national fractional count, which allows to assess more objectively the contribution of organizations and researchers to the gross scientific product and does not demotivate participation in international collaborations. We performed a detailed comparison of the article and national fractional counts in 2018, as well as in dynamics over the period 2000-2018 and in the fields of science for the three groups of organizations. Comparison shows the increasing variation of fractional and article counting results. <br>
DOI: 10.6084/m9.figshare.28366964.v1
title: <b>Interdisciplinary Team-Based Learning Workshop for Periodontic and Endodontic Postgraduate Residents: A Descriptive Study</b>

description: This data is about Perception of working in a dental clinic and psychological well being index of a group of trainee Dental Surgery assistants before and after mental wellness module.
DOI: 10.6084/m9.figshare.28522076.v1
title: Supplementary Material for: Home-based dialysis and person-centered care: A scoping review

description: Introduction
Managing dialysis at home requires the involvement of the patient in decisions, treatment, and their illness and health. Evidence-based person-centered care interventions focus on listening to the patient's narrative, establishing a partnership between patients and healthcare professionals, and documenting care and treatment in a shared health plan. Therefore, a person-centered care intervention is expected to enhance the patient's ability to manage dialysis at home. This study aimed to identify and map evidence for person-centered interventions and home-based dialysis for individuals with kidney failure.
Methods
A scoping review was conducted based on the approach of Arksey and O'Malley. A systematic search was carried out in Medline, CINAHL, and Scopus for articles in all languages and without time restrictions. Person-centered care interventions concerning home dialysis were included. Two independent researchers assessed the literature. Data were extracted using NVIVO, and a relational analytical framework was employed to synthesise the data.
Results
The search identified 9,443 articles, of which 16 met the inclusion criteria. A total of 13 person-centered care interventions were identified. Eight interventions aimed to involve the patient in the decision regarding the type of dialysis modality, with six interventions identified to involve the patient in treatment, illness, and health. Only one intervention was identified to involve the patient in the decisions that follow once the patient has commenced dialysis treatment. Five interventions showed a correlation between a person-centered care intervention and the number of patients in home dialysis.
Conclusion
There is a need for interventions for patients in home dialysis to be adapted to a more person-centered care approach, particularly regarding the involvement of the patient in their treatment, illness and health, as well as the decisions that follow the initiation of dialysis treatment.
DOI: 10.6084/m9.figshare.15172536.v1
title: Molecular modelling on SARS-CoV-2 papain-like protease: an integrated study with homology modelling, molecular docking, and molecular dynamics simulations

description: SARS-CoV-2 PLpro was investigated as a therapeutic target for potent antiviral drugs due to its essential role in not only viral replication but also in regulating the inborn immune response. Several computational approaches, including homology modelling, molecular docking, and molecular dynamics (MD) studies, were employed to search for promising drugs in treating SARS-CoV-2. Eighty-one compounds, sub-structurally similar to the antiviral drug, were used as potential inhibitors of PLpro. From our results, three complexes containing the ligands with Pubchem IDs: 153012995, 12149203, and 123608715 showed lower binding energies than the control (Ritonavir), indicating that they may become promising inhibitors for PLpro. MD was performed in a water solvent to validate the stability of the three complexes. All complexes achieved stable structure during the simulation as no significant fluctuations were observed in the validation parameters. Moreover, the binding energy for each complex was estimated using the MM-GBSA method. Complex 1 was the most stable structure based on the lowest binding energy score and its structure remained in a similar cavity with the docket snapshot. Based on our studies, three ligands were assumed to be potential inhibitors. The ligand of complex 1 may become the most promising antiviral drug against SARS-CoV-2 targeting PLpro.
DOI: 10.6084/m9.figshare.19090271.v1
title: California city tree inventories

description: A cleaned and standardized set of publicly available municipal tree inventories for cities in the state of California. Inventories were gathered in 2020, but were not necessarily up to date at that time. Scientific names have been standardized, but common names (when provided) have not. Sources and information can be found in the file "CA tree inventory data sources.xlsx"<br>
DOI: 10.6084/m9.figshare.6244346.v1
title: Hawaii FEF dataset and analysis

description: Analysis of fungal ITS1 sequence data from the interior of leaves from native Hawaiian plants. <br>
DOI: 10.6084/m9.figshare.28722119.v1
title: Table_S9.rank_genes_immune_time.csv

description: <b>Table S9. </b>Differentially expressed genes (DEGs) in brain tumor-associated immune cells, 7 vs 28d post GL261-GSCs implantation. Related to Figures 5 D-F and suppl. 5 C-D.
DOI: 10.6084/m9.figshare.19653825.v2
title: A Raman Spectroscopic Perspective of the Chang’E-5 Lunar Soils

description: Data for the manuscript submitted to GRL (i.e., A Raman Spectroscopic Perspective of the Chang’E-5 Lunar Soils) <br>