cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.8195234
title: Evaluation of food baits to capture Drosophila suzukii in the southern of Brazil

description: Abstract: Drosophila suzukii is one of the main pests of small fruits in the world. An effective monitoring is fundamental to detect the presence of the fly and to predict the infestation of fruits in new areas. We evaluated the food baits Ceratrap®, Torula®, Biofruit®, Suzukii Trap®, apple cider vinegar, and a homemade mixture comprising wine, vinegar and molasses (WVM) for D. suzukii attractiveness, and if reproductive stage affects females attraction and capture in the different baits. Bait selectivity of non-target insects was assessed. The preference of adults between ripe blackberry fruit and the food baits was also evaluated. Adults showed a higher attraction (61.97% of the captured insects) to the WVM mixture than to Ceratrap® (1.32%), Torula® (0.52%), Biofruit® (13.15%), Suzukii Trap® (17.6%), and apple vinegar (5.4%). Considering the attractiveness to D. suzukii, Suzukii Trap® and apple vinegar were the most selective to non-target insects. In general, reproductively immature females showed a preference for Biofruit®, apple vinegar, and WVM, whereas mature females did not show bait preferences. Adults preferred ripe blackberry fruit over the WVM mixture. Understanding the field behavior of D. suzukii is of foremost importance to estimate insect population density and outline pest management strategies.
DOI: 10.6084/m9.figshare.8195240
title: The compound, diallyl disulfide, enriched in garlic, prevents the progression of doxorubicin-induced nephropathy

description: Abstract The main medicinal property of garlic is mostly attributed to its organosulfur compounds, of which the oil-soluble diallyl disulfide (DADS) is the principal component of distilled garlic oil. Nuclear factor erythroid 2-related factor 2 (Nrf2) is an important cellular regulator in response to oxidative stress. This study assessed the possible protective effect of DADS on doxorubicin (Dox)-induced nephrotoxicity and its potential regulation of the Nrf2 pathway. Treatment with DADS (200 μM) induced heme oxygenase (HO)-1 and NADPH quinone oxidoreductase 1 (NQO-1) expression in a human proximal tubular cell line. The induction of HO-1 expression was suppressed in Nrf2-silenced cells. In an animal study, pretreatment with DADS relieved Dox-induced albuminuria, increased catalase activity, and reduced the urinary 8-hydroxy-2'-deoxyguanosine level. In addition, DADS ameliorated the severity of glomerulosclerosis and suppressed expressions of fibrotic and inflammatory gene expressions. Our data indicate that DADS, a major component of garlic, showed protective effects of preventing the progression of Dox-induced nephropathy through enhancing Nrf2-mediated antioxidant activity. DADS, a normal constituent of the human diet, merits investigation as a potential antioxidant daily food supplement against free radical-mediated chronic diseases.
DOI: 10.6084/m9.figshare.8195273
title: Beyond Traditional Health Training: Experience of Popular Education in Medical Training

description: ABSTRACT In recent years medical training has been at the heart of different discussions and policies. Despite the evolutionary process of Brazilian medical education, whether in its curricular or methodological aspects, there are still important gaps to be filled, in order to guarantee an comprehensive and humanistic education. It has become évident that transforming the methodologies and the curriculum does not go far enough; it is fundamental to introduce students into spaces of reflection, that can have a positive affect on their «existential worlds”. One possible tool for building such spaces would be university extension programs, understood as an interdisciplinary, educational, cultural, scientific and political process capable of fostering interaction between the University and the most diverse sectors of society, transforming them mutually. Thus, this article presents and analyzes the impacts of an extensionist action, based on Popular Health Education in a settlement in innerstate Bahia, on the training of medical students, according to their perceptions. Content analysis was applied to the field diaries and semi-structured interviews of ten medical students participating in the program «Social participation and the right to health: intersectoral planning, art, social mobilization and popular education in a settlement in Bahia». The results indicate that the traditional teaching of medicine often neglects the human being in all its potential, as well as its social, political and cultural context. The curriculum offers little possibility for real community-based practice; practical activities are often confined to the hospital setting; there are few opportunities for exchanges and dialogues with students from other undergraduate courses. Thus, it is concluded that university extension can favor important processes of transformation in medical education by enabling a broad understanding of individuals, their relationships and their ways of living in the world.
DOI: 10.6084/m9.figshare.8195273.v1
title: Beyond Traditional Health Training: Experience of Popular Education in Medical Training

description: ABSTRACT In recent years medical training has been at the heart of different discussions and policies. Despite the evolutionary process of Brazilian medical education, whether in its curricular or methodological aspects, there are still important gaps to be filled, in order to guarantee an comprehensive and humanistic education. It has become évident that transforming the methodologies and the curriculum does not go far enough; it is fundamental to introduce students into spaces of reflection, that can have a positive affect on their «existential worlds”. One possible tool for building such spaces would be university extension programs, understood as an interdisciplinary, educational, cultural, scientific and political process capable of fostering interaction between the University and the most diverse sectors of society, transforming them mutually. Thus, this article presents and analyzes the impacts of an extensionist action, based on Popular Health Education in a settlement in innerstate Bahia, on the training of medical students, according to their perceptions. Content analysis was applied to the field diaries and semi-structured interviews of ten medical students participating in the program «Social participation and the right to health: intersectoral planning, art, social mobilization and popular education in a settlement in Bahia». The results indicate that the traditional teaching of medicine often neglects the human being in all its potential, as well as its social, political and cultural context. The curriculum offers little possibility for real community-based practice; practical activities are often confined to the hospital setting; there are few opportunities for exchanges and dialogues with students from other undergraduate courses. Thus, it is concluded that university extension can favor important processes of transformation in medical education by enabling a broad understanding of individuals, their relationships and their ways of living in the world.
DOI: 10.6084/m9.figshare.8195291
title: Prostate brachytherapy with iodine-125 seeds: analysis of a single institutional cohort

description: ABSTRACT  Objectives: Brachytherapy (BT) with iodine-125 seeds placement is a consolidated treatment for prostate cancer. The objective of this study was to assess the clinical outcomes in patients with prostate cancer who underwent low-dose-rate (LDR) -BT alone in a single Brazilian institution.  Materials and Methods: Patients treated with iodine-125 BT were retrospectively assessed after at least 5 years of follow-up. Patients who received combination therapy (External beam radiation therapy-EBRT and BT) and salvage BT were not included.  Results: 406 men were included in the study (65.5% low-risk, 30% intermediate-risk, and 4.5% high-risk patients). After a median follow-up of 87.5 months, 61 (15.0%) patients developed biochemical recurrence. The actuarial biochemical failure-free survival (BFFS) at 5 and 10 years were 90.6% and 82.2%, respectively. A PSA nadir ≥ 1 ng / mL was associated with a higher risk of biochemical failure (HR = 5.81; 95% CI: 3.39 to 9.94; p ≤ 0.001). The actuarial metastasis-free survival (MFS) at 5 and 10 years were 98.3% and 94%, respectively. The actuarial overall survival (OS) at 5 and 10 years were 96.2% and 85.1%, respectively. Acute and late grade 2 and 3 gastrointestinal toxicities were observed in 5.6%, 0.5%, 4.6% and 0.5% of cases, respectively. For genitourinary the observed acute and late grade 2 and 3 toxicities rates were 57.3%, 3.6%, 28% and 3.1%, respectively. No grade 4 and 5 were observed.  Conclusions: BT was effective as a definitive treatment modality for prostate cancer, and its endpoints and toxicities were comparable to those of the main series in the literature.
DOI: 10.6084/m9.figshare.8195306
title: Elemental concentration via portable x-ray fluorescence spectrometry: Assessing the impact of water content

description: ABSTRACT Portable X-ray fluorescence (pXRF) analysis can be considered one of the main recent advances for chemical characterization of earth materials. The water content of the samples can affect the pXRF performance. As a novelty, we aimed to establish relationships (linear regression) between the effect of water content on pXRF results and atomic number (Z) of the elements. Three certified reference materials (CRM) were investigated: OREAS 100a, OREAS 101a, and OREAS 101b. These materials were saturated (0.68 g g-1) with distilled water and left to air-dry naturally. During the drying, the elemental concentrations (C) were determined at different water contents using a pXRF spectrometer. For each water content, the ratio Cwet/Cdry was determined and plotted against the water content. The attenuation coefficient (σ) was also determined. High σ values mean more influence of water content upon measurement element concentration. The obtained recovery rates allowed a qualitative determination. The concentration for the most elements reduced linearly with increasing water content. A predictable behavior of the water content on pXRF results as function of atomic number was not found. Elements identified by Lα spectral line with highest Z were more impacted by water content than elements identified by Kα line with lowest Z. Ti, Cr and Fe was not significantly influenced by water content, and Sr was the most impacted. Our findings contribute to decision-making before characterization earth materials via pXRF, obliging the use of dry samples for determination of impacted elements or by using moisture-corrected data.
DOI: 10.6084/m9.figshare.8195315.v1
title: Inhibitory Effect on the Hepatitis B Cells through the Regulation of miR-122-MAP3K2 signal pathway

description: Abstract: The aim of this study was to investigate the inhibitory effect of regulation of miR-122-MAP3K2 signal pathway on the hepatitis B cells. We detected the content of MAP3K2 from patients with HBV blood serum samples and analyzed the correlation between content of MAP3K2 and copies of HBV-DNA. Wound healing and Transwell assays were used to detect the function of cells from control group (wild type) and observer group (overexpresses miR-122). Secretion levels of HBsAg and MAP3K2 in the supernatant and level of MAP3K2 in cells were detected by ELISA and western blot, respectively. The results showed that there was a positive correlation between the copies of HBV-DNA and MAP3K2 in serum. In the assays involving detection of the number of HBV-DNA copies, the supernatant levels of HBsAg and MAP3K2, and the level of MAP3K2 in the cells, the rate of increase of these indicators significantly slowed as culture time. In conclusion, overexpression of miR-122 could inhibit the migration of hepatoblastoma cells; however, following transfection with miR-122, DNA synthesis and the secretion of HBsAg were inhibited. Overexpression of miR-122 can also downregulate MAP3K2. Consequently, we concluded that regulating the miR-122-MAP3K2 signaling pathway exerts an inhibitory effect in hepatitis B cells.
DOI: 10.6084/m9.figshare.8195507
title: A Bibliography of David K. McAlpine

description: A complete list of the 161 publications of the Australian Museum dipterist—David K. McAlpine—is presented. This list is compiled under Dr McAlpine’s oversight and has benefited from his input throughout. It includes reports, notes presented at meetings, and published newspaper or magazine pieces, many of which Dr McAlpine describes as popular or informal. A list of 103 peer-reviewed works (a subset of the present list) is published separately by Cox & McEvey (2019).
DOI: 10.6084/m9.figshare.8196062
title: Additional file 3: of Transposon libraries identify novel Mycobacterium bovis BCG genes involved in the dynamic interactions required for BCG to persist during in vivo passage in cattle

description: Differences in in vitro fitness between BCG Danish and BCG Pasteur input libraries. Output from the genomic comparisons of the two input libraries describing relative in vitro fitness between BCG Danish and BCG Pasteur. (XLSX 241 kb)
DOI: 10.6084/m9.figshare.8196062.v1
title: Additional file 3: of Transposon libraries identify novel Mycobacterium bovis BCG genes involved in the dynamic interactions required for BCG to persist during in vivo passage in cattle

description: Differences in in vitro fitness between BCG Danish and BCG Pasteur input libraries. Output from the genomic comparisons of the two input libraries describing relative in vitro fitness between BCG Danish and BCG Pasteur. (XLSX 241 kb)
DOI: 10.6084/m9.figshare.8196116
title: MOESM2 of Generalist host species drive Trypanosoma cruzi vector infection in oil palm plantations in the Orinoco region, Colombia

description: Additional file 2. 12S DNA reference database of vertebrate species from GenBank.
DOI: 10.6084/m9.figshare.8196125.v1
title: MOESM3 of Generalist host species drive Trypanosoma cruzi vector infection in oil palm plantations in the Orinoco region, Colombia

description: Additional file 3. 12S DNA taxonomy file of vertebrate species from GenBank.
DOI: 10.6084/m9.figshare.8195282.v1
title: Relationship between periodontal outcomes and serum biomarkers changes after non-surgical periodontal therapy

description: Abstract: The systemic effect of chronic periodontitis (CP) has been suggested by several studies as an etiologic factor and modulator of diseases based on the changes in the inflammatory marker levels. This study aimed to investigate the relationship between the changes in clinical periodontal outcomes and serum biomarkers (CRP, IL-6, albumin and percentage of leukocytes) after non-surgical periodontal therapy in systemically healthy adults. An interventional study was conducted with a sample of 29 individuals without CP (control group) and 33 with CP (CP group). Periodontal clinical variables were recorded, and the serum levels of inflammatory markers were measured. Statistical analysis included the chi-square and Student’s t-tests and Pearson’s correlation analysis. After 90 days of non-surgical periodontal treatment, a reduction of periodontal parameters and IL-6 in both groups could be observed (P &lt; 0.001). The correlation analysis revealed a directly proportional correlation between changes in the probing depth (r = 0.349, P = 0.049) and clinical attachment level (r = 0.374, P = 0.034) with CRP in the CP group. The findings suggest a reduction of IL-6 serum concentration and periodontal clinical measures 90 days after periodontal therapy in both groups.
DOI: 10.6084/m9.figshare.8195300
title: Biochar association with phosphate fertilizer and its influence on phosphorus use efficiency by maize

description: ABSTRACT The use of fertilizers with some degree of protection of the phosphate ions can reduce soil adsorption and increase the absorption by plants, increasing the efficiency of phosphorus (P) fertilization. This study aimed to evaluate the performance of a phosphate fertilizer associated with biochar in granules in a P-fixing soil in a greenhouse experiment. Biochars were produced from two sources of biomass: sugarcane bagasse (SB) and wood sawdust (WS), which were pyrolysed at two temperatures (350 °C and 700 °C). After chemical and physical characterization, the biochar samples were granulated with triple superphosphate (TSP) in a 3:1 ratio (TSP: biochar). The agronomic evaluation of the fertilizers was carried out by two successive maize crops (Zea mays L.) in the greenhouse, using a factorial scheme of (5x3) in randomized block design with four replicates. The treatments consisted of five fertilizers (TSP-WS350, TSP-WS700, TSP-SB350, TSP-SB700, and TSP) and three P doses (100, 200, and 400 mg dm-3). It was evaluated the dry matter production, P uptake in maize and P available in the soil after cultivation. The results indicate that dry matter production, considering the P uptake by the plant and the P available in the soil when using a dose of 400 mg dm-3, presented higher results in both crop cycles and the recovery rate in both cultivations occurred inversely to the P doses. The simple association of biochar with soluble phosphate fertilizer did not increase the efficiency of P use by maize, but it increased available P in soil.
DOI: 10.6084/m9.figshare.8196116.v1
title: MOESM2 of Generalist host species drive Trypanosoma cruzi vector infection in oil palm plantations in the Orinoco region, Colombia

description: Additional file 2. 12S DNA reference database of vertebrate species from GenBank.
DOI: 10.6084/m9.figshare.8196125
title: MOESM3 of Generalist host species drive Trypanosoma cruzi vector infection in oil palm plantations in the Orinoco region, Colombia

description: Additional file 3. 12S DNA taxonomy file of vertebrate species from GenBank.
DOI: 10.6084/m9.figshare.8196158.v1
title: Additional file 1 of Capturing the differences between humoral immunity in the normal and tumor environments from repertoire-seq of B-cell receptors using supervised machine learning

description: Table S1. A table showing the number of reads, inferred reads, unique reads, clones, and extracted clones for each sample. (XLS 33 kb)
DOI: 10.6084/m9.figshare.8196167
title: Additional file 1: of Transcriptome analysis of the model grass Lolium temulentum exposed to green leaf volatiles

description: Table S1. List of primers for selected DES used for qRT-PCR expression analysis. This table contains, DES gene name, qPCR primers, amplicon length, annelling temperatures and efficiency (XLSX 9 kb)
DOI: 10.6084/m9.figshare.8196167.v1
title: Additional file 1: of Transcriptome analysis of the model grass Lolium temulentum exposed to green leaf volatiles

description: Table S1. List of primers for selected DES used for qRT-PCR expression analysis. This table contains, DES gene name, qPCR primers, amplicon length, annelling temperatures and efficiency (XLSX 9 kb)
DOI: 10.6084/m9.figshare.8196173.v1
title: Additional file 2: of Transcriptome analysis of the model grass Lolium temulentum exposed to green leaf volatiles

description: Table S2. Table of sequence read counts and percent alignments, at 1, 2, and 6â  h time points and their corresponding untreated controls. (XLSX 45 kb)
DOI: 10.6084/m9.figshare.8196176.v1
title: Additional file 3: of Transcriptome analysis of the model grass Lolium temulentum exposed to green leaf volatiles

description: Table S3. Table describing the GLV transcriptome values, contig length range and # of unique sequences (XLSX 40 kb)
DOI: 10.6084/m9.figshare.8196182
title: Additional file 4: of Transcriptome analysis of the model grass Lolium temulentum exposed to green leaf volatiles

description: Table S4. List of DES on spreadsheets for the up- or down-regulated DES at 1, 2, and 6â  h time points. These spreadsheets contain the identified nucleotide sequences, annotation, Reads Per Kilobase Million and log2 values for GLV treated samples and their corresponding untreated controls, p-values, FDR and GO terms are on separate spreadsheets for the up- or down-regulated DES at each time point. (XLSX 2883 kb)
DOI: 10.6084/m9.figshare.8196182.v1
title: Additional file 4: of Transcriptome analysis of the model grass Lolium temulentum exposed to green leaf volatiles

description: Table S4. List of DES on spreadsheets for the up- or down-regulated DES at 1, 2, and 6â  h time points. These spreadsheets contain the identified nucleotide sequences, annotation, Reads Per Kilobase Million and log2 values for GLV treated samples and their corresponding untreated controls, p-values, FDR and GO terms are on separate spreadsheets for the up- or down-regulated DES at each time point. (XLSX 2883 kb)
DOI: 10.6084/m9.figshare.8196188
title: Additional file 5: of Transcriptome analysis of the model grass Lolium temulentum exposed to green leaf volatiles

description: Table S5. List of DES on spreadsheets for the up- or down-regulated DES Venn comparisons at 1, 2, and 6â  h time points. These spreadsheets contain the locus designations, annotation and GO terms, and log2 values for GLV treated samples and their corresponding untreated controls, for the up- or down-regulated DES for each related group shown in the Venn diagrams (Fig. 3). (XLSX 884 kb)
DOI: 10.6084/m9.figshare.8196188.v1
title: Additional file 5: of Transcriptome analysis of the model grass Lolium temulentum exposed to green leaf volatiles

description: Table S5. List of DES on spreadsheets for the up- or down-regulated DES Venn comparisons at 1, 2, and 6â  h time points. These spreadsheets contain the locus designations, annotation and GO terms, and log2 values for GLV treated samples and their corresponding untreated controls, for the up- or down-regulated DES for each related group shown in the Venn diagrams (Fig. 3). (XLSX 884 kb)
DOI: 10.6084/m9.figshare.8196254.v1
title: Additional file 4: of Millennial-scale variability of East Asian summer monsoon inferred from sea surface salinity in the northern East China Sea (ECS) and its impact on the Japan Sea during Marine Isotope Stage (MIS) 3

description: Table S1. The tie points of the fine-tuned age model of KR07-12 PC-01. (XLS 27 kb)
DOI: 10.6084/m9.figshare.8196053
title: Additional file 2: of Transposon libraries identify novel Mycobacterium bovis BCG genes involved in the dynamic interactions required for BCG to persist during in vivo passage in cattle

description: The predicted essentiality and in vivo fitness of BCG genes. Output from the comparisons between the input and output libraries, describing the relative fitness of each gene during passage through the cattle. (XLSX 2251 kb)
DOI: 10.6084/m9.figshare.8196275.v1
title: Additional file 2: of Prognostic value of B cells in cutaneous melanoma

description: Table S1. All count/nucleotide/diversity measurements for each sample. Table S2 Classification information for each sample. (XLSX 560 kb)
DOI: 10.6084/m9.figshare.8196173
title: Additional file 2: of Transcriptome analysis of the model grass Lolium temulentum exposed to green leaf volatiles

description: Table S2. Table of sequence read counts and percent alignments, at 1, 2, and 6â  h time points and their corresponding untreated controls. (XLSX 45 kb)
DOI: 10.6084/m9.figshare.8196176
title: Additional file 3: of Transcriptome analysis of the model grass Lolium temulentum exposed to green leaf volatiles

description: Table S3. Table describing the GLV transcriptome values, contig length range and # of unique sequences (XLSX 40 kb)
DOI: 10.6084/m9.figshare.8196254
title: Additional file 4: of Millennial-scale variability of East Asian summer monsoon inferred from sea surface salinity in the northern East China Sea (ECS) and its impact on the Japan Sea during Marine Isotope Stage (MIS) 3

description: Table S1. The tie points of the fine-tuned age model of KR07-12 PC-01. (XLS 27 kb)