cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.60712/si-id14454.1
title: StrainInfo SI-ID 14454.1

description: StrainInfo dataset 14454 about a strain of Pseudomonas aeruginosa. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.60712/si-id14455.1
title: StrainInfo SI-ID 14455.1

description: StrainInfo dataset 14455 about a strain of Pseudomonas aeruginosa. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.60712/si-id14456.1
title: StrainInfo SI-ID 14456.1

description: StrainInfo dataset 14456 about a strain of Pseudomonas aeruginosa. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.60712/si-id14457.1
title: StrainInfo SI-ID 14457.1

description: StrainInfo dataset 14457 about a strain of Chryseobacterium joostei. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.60712/si-id14465.1
title: StrainInfo SI-ID 14465.1

description: StrainInfo dataset 14465 about a strain of Bradyrhizobium. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.60712/si-id14361.1
title: StrainInfo SI-ID 14361.1

description: StrainInfo dataset 14361 about a strain of Ralstonia. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.60712/si-id14362.1
title: StrainInfo SI-ID 14362.1

description: StrainInfo dataset 14362 about a strain of Unidentified. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.60712/si-id14458.1
title: StrainInfo SI-ID 14458.1

description: StrainInfo dataset 14458 about a strain of Unidentified. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.60712/si-id14459.1
title: StrainInfo SI-ID 14459.1

description: StrainInfo dataset 14459 about a strain of Bradyrhizobium. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.60712/si-id14460.1
title: StrainInfo SI-ID 14460.1

description: StrainInfo dataset 14460 about a strain of Rhizobium. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.60712/si-id14461.1
title: StrainInfo SI-ID 14461.1

description: StrainInfo dataset 14461 about a strain of Bradyrhizobium. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.60712/si-id14466.1
title: StrainInfo SI-ID 14466.1

description: StrainInfo dataset 14466 about a strain of Azomonas insignis. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.60712/si-id14467.1
title: StrainInfo SI-ID 14467.1

description: StrainInfo dataset 14467 about a strain of Schinkia azotoformans. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.60712/si-id14468.1
title: StrainInfo SI-ID 14468.1

description: StrainInfo dataset 14468 about a strain of Virgibacillus pantothenticus. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.60712/si-id14469.1
title: StrainInfo SI-ID 14469.1

description: StrainInfo dataset 14469 about a strain of Acidovorax. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.60712/si-id14566.1
title: StrainInfo SI-ID 14566.1

description: StrainInfo dataset 14566 about a strain of Acetobacter pasteurianus. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.20372/aau_rdm/ewbz6t
title: Analgesic and Antinflammatory Activities of the Root Extract of Grewia schweinfurthii and its Constituent and Determination of Nutritional and Antinutritional Compositions of its Fruit

description: The Data was Analgesic and Antinflammatory Activities of the Root extract of Grewia schweinfurthii and its Constituent and Determination of Nutritional and Antinutritional Compositions of its Fruit
DOI: 10.60712/si-id14567.1
title: StrainInfo SI-ID 14567.1

description: StrainInfo dataset 14567 about a strain of Gluconacetobacter liquefaciens. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.60712/si-id14462.1
title: StrainInfo SI-ID 14462.1

description: StrainInfo dataset 14462 about a strain of Bradyrhizobium. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.60712/si-id14470.1
title: StrainInfo SI-ID 14470.1

description: StrainInfo dataset 14470 about a strain of Mesorhizobium plurifarium. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.60712/si-id14471.1
title: StrainInfo SI-ID 14471.1

description: StrainInfo dataset 14471 about a strain of Mesorhizobium plurifarium. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.60712/si-id14472.1
title: StrainInfo SI-ID 14472.1

description: StrainInfo dataset 14472 about a strain of Niallia circulans. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.60712/si-id14473.1
title: StrainInfo SI-ID 14473.1

description: StrainInfo dataset 14473 about a strain of Lacticaseibacillus manihotivorans. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.60712/si-id14570.1
title: StrainInfo SI-ID 14570.1

description: StrainInfo dataset 14570 about a strain of Acetobacter. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.60712/si-id14571.1
title: StrainInfo SI-ID 14571.1

description: StrainInfo dataset 14571 about a strain of Acetobacter pasteurianus. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.60712/si-id14572.1
title: StrainInfo SI-ID 14572.1

description: StrainInfo dataset 14572 about a strain of Acetobacter pasteurianus. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.60712/si-id14676.1
title: StrainInfo SI-ID 14676.1

description: StrainInfo dataset 14676 about a strain of Enterococcus faecium. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.60712/si-id14677.1
title: StrainInfo SI-ID 14677.1

description: StrainInfo dataset 14677 about a strain of Enterococcus faecalis. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.60712/si-id14474.1
title: StrainInfo SI-ID 14474.1

description: StrainInfo dataset 14474 about a strain of Weissella confusa. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.60712/si-id14475.1
title: StrainInfo SI-ID 14475.1

description: StrainInfo dataset 14475 about a strain of Bacillus. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.60712/si-id14476.1
title: StrainInfo SI-ID 14476.1

description: StrainInfo dataset 14476 about a strain of Unidentified. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.60712/si-id14573.1
title: StrainInfo SI-ID 14573.1

description: StrainInfo dataset 14573 about a strain of Acetobacter pasteurianus. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.60712/si-id14574.1
title: StrainInfo SI-ID 14574.1

description: StrainInfo dataset 14574 about a strain of Acetobacter pasteurianus. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.60712/si-id14575.1
title: StrainInfo SI-ID 14575.1

description: StrainInfo dataset 14575 about a strain of Acetobacter pasteurianus. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.60712/si-id14576.1
title: StrainInfo SI-ID 14576.1

description: StrainInfo dataset 14576 about a strain of Acetobacter pasteurianus. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.60712/si-id14678.1
title: StrainInfo SI-ID 14678.1

description: StrainInfo dataset 14678 about a strain of Enterococcus faecalis. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.60712/si-id14679.1
title: StrainInfo SI-ID 14679.1

description: StrainInfo dataset 14679 about a strain of Enterococcus faecalis. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.60712/si-id14680.1
title: StrainInfo SI-ID 14680.1

description: StrainInfo dataset 14680 about a strain of Enterococcus faecalis. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.60712/si-id14681.1
title: StrainInfo SI-ID 14681.1

description: StrainInfo dataset 14681 about a strain of Enterococcus durans. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.60712/si-id14477.1
title: StrainInfo SI-ID 14477.1

description: StrainInfo dataset 14477 about a strain of Bacillus. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.60712/si-id14478.1
title: StrainInfo SI-ID 14478.1

description: StrainInfo dataset 14478 about a strain of Peribacillus simplex. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.60712/si-id14479.1
title: StrainInfo SI-ID 14479.1

description: StrainInfo dataset 14479 about a strain of Unidentified. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.60712/si-id14480.1
title: StrainInfo SI-ID 14480.1

description: StrainInfo dataset 14480 about a strain of Neobacillus fumarioli. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.60712/si-id14578.1
title: StrainInfo SI-ID 14578.1

description: StrainInfo dataset 14578 about a strain of Acetobacter pasteurianus. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.60712/si-id14579.1
title: StrainInfo SI-ID 14579.1

description: StrainInfo dataset 14579 about a strain of Acetobacter pasteurianus. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.6084/m9.figshare.25400130
title: Assessment of cytochrome P450 induction in canine intestinal organoid models

description: Understanding cytochrome P450 (CYP) enzymes in the canine intestine is vital for predicting drug metabolism and developing safer oral medications. This study evaluates canine colonoids as a model to assess the expression and induction of essential intestinal CYP enzymes.Canine colonoids were cultured in expansion medium (EM) with Wnt-3A and in differentiation medium (DM) without Wnt-3A. We assessed the mRNA expression of <i>CYP2B11</i>, <i>CYP2C21</i>, <i>CYP3A12</i>, and <i>CYP3A98</i> using qPCR and examined the effects of rifampicin and phenobarbital as inducers.Our findings show that DM significantly increased the mRNA expression of <i>CYP3A98</i> and <i>CYP2B11</i>, but not <i>CYP3A12</i>, compared to EM. <i>CYP2C21</i>, not typically expressed in the intestine, remained unexpressed in colonoids. Rifampicin induced CYP3A98, aligning with pregnane x receptor (PXR) regulation, while phenobarbital did not, suggesting no constitutive androstane receptor (CAR) involvement. CYP2B11 did not respond to either inducer, suggesting alternative regulatory pathways in canine colonoids.This study is a pioneering effort to establish conditions for studying P450 expression in canine colonoids, confirming significant CYP3A98 expression in the canine intestine. It demonstrated colonoids can induce CYP activity post drug treatments. Further research is needed to enhance species-specific drug metabolism understanding and validate this model for broader applications. Understanding cytochrome P450 (CYP) enzymes in the canine intestine is vital for predicting drug metabolism and developing safer oral medications. This study evaluates canine colonoids as a model to assess the expression and induction of essential intestinal CYP enzymes. Canine colonoids were cultured in expansion medium (EM) with Wnt-3A and in differentiation medium (DM) without Wnt-3A. We assessed the mRNA expression of <i>CYP2B11</i>, <i>CYP2C21</i>, <i>CYP3A12</i>, and <i>CYP3A98</i> using qPCR and examined the effects of rifampicin and phenobarbital as inducers. Our findings show that DM significantly increased the mRNA expression of <i>CYP3A98</i> and <i>CYP2B11</i>, but not <i>CYP3A12</i>, compared to EM. <i>CYP2C21</i>, not typically expressed in the intestine, remained unexpressed in colonoids. Rifampicin induced CYP3A98, aligning with pregnane x receptor (PXR) regulation, while phenobarbital did not, suggesting no constitutive androstane receptor (CAR) involvement. CYP2B11 did not respond to either inducer, suggesting alternative regulatory pathways in canine colonoids. This study is a pioneering effort to establish conditions for studying P450 expression in canine colonoids, confirming significant CYP3A98 expression in the canine intestine. It demonstrated colonoids can induce CYP activity post drug treatments. Further research is needed to enhance species-specific drug metabolism understanding and validate this model for broader applications.
DOI: 10.6084/m9.figshare.25400130.v1
title: Assessment of cytochrome P450 induction in canine intestinal organoid models

description: Understanding cytochrome P450 (CYP) enzymes in the canine intestine is vital for predicting drug metabolism and developing safer oral medications. This study evaluates canine colonoids as a model to assess the expression and induction of essential intestinal CYP enzymes.Canine colonoids were cultured in expansion medium (EM) with Wnt-3A and in differentiation medium (DM) without Wnt-3A. We assessed the mRNA expression of <i>CYP2B11</i>, <i>CYP2C21</i>, <i>CYP3A12</i>, and <i>CYP3A98</i> using qPCR and examined the effects of rifampicin and phenobarbital as inducers.Our findings show that DM significantly increased the mRNA expression of <i>CYP3A98</i> and <i>CYP2B11</i>, but not <i>CYP3A12</i>, compared to EM. <i>CYP2C21</i>, not typically expressed in the intestine, remained unexpressed in colonoids. Rifampicin induced CYP3A98, aligning with pregnane x receptor (PXR) regulation, while phenobarbital did not, suggesting no constitutive androstane receptor (CAR) involvement. CYP2B11 did not respond to either inducer, suggesting alternative regulatory pathways in canine colonoids.This study is a pioneering effort to establish conditions for studying P450 expression in canine colonoids, confirming significant CYP3A98 expression in the canine intestine. It demonstrated colonoids can induce CYP activity post drug treatments. Further research is needed to enhance species-specific drug metabolism understanding and validate this model for broader applications. Understanding cytochrome P450 (CYP) enzymes in the canine intestine is vital for predicting drug metabolism and developing safer oral medications. This study evaluates canine colonoids as a model to assess the expression and induction of essential intestinal CYP enzymes. Canine colonoids were cultured in expansion medium (EM) with Wnt-3A and in differentiation medium (DM) without Wnt-3A. We assessed the mRNA expression of <i>CYP2B11</i>, <i>CYP2C21</i>, <i>CYP3A12</i>, and <i>CYP3A98</i> using qPCR and examined the effects of rifampicin and phenobarbital as inducers. Our findings show that DM significantly increased the mRNA expression of <i>CYP3A98</i> and <i>CYP2B11</i>, but not <i>CYP3A12</i>, compared to EM. <i>CYP2C21</i>, not typically expressed in the intestine, remained unexpressed in colonoids. Rifampicin induced CYP3A98, aligning with pregnane x receptor (PXR) regulation, while phenobarbital did not, suggesting no constitutive androstane receptor (CAR) involvement. CYP2B11 did not respond to either inducer, suggesting alternative regulatory pathways in canine colonoids. This study is a pioneering effort to establish conditions for studying P450 expression in canine colonoids, confirming significant CYP3A98 expression in the canine intestine. It demonstrated colonoids can induce CYP activity post drug treatments. Further research is needed to enhance species-specific drug metabolism understanding and validate this model for broader applications.