cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.18150/lp4i0u
title: Data related to the work entitled Spectroscopic studies under properties of chlorpromazine conjugated to gold nanoparticles

description: Our research focuses on developing synthesis techniques for conjugating chlorpromazine (CPZ), a neuroleptic drug, with gold nanoparticles (AuNPs). The CPZ-AuNP conjugates were synthesized via a ligand exchange reaction on quasi-spherical, negatively charged citrate-stabilized TC-AuNPs, averaging 55 ± 5 nm in diameter. UV–vis spectroscopy was used to assess the stability of the conjugates under varying pH levels and ionic strengths. Electrokinetic measurements revealed that the zeta potential of the CPZ-AuNP conjugates is highly dependent on the amount of CPZ adsorbed onto the nanoparticle surface. Notably, the conjugates displayed an isoelectric point at pH 8.8. To investigate the adsorption structure of CPZ on the TC-AuNPs, surface-enhanced Raman spectroscopy (SERS) and surface-enhanced infrared absorption spectroscopy (SEIRA) were utilized. Spectral interpretation was supported by Raman and FTIR data for CPZ, as well as Density Functional Theory (DFT) calculations. The findings suggest that CPZ binds to the nanoparticle surface primarily through the phenothiazine ring and propylene bridge, both oriented at an angle. Moreover, the C-N-C fragment was found to interact with the TC-AuNP surface in a perpendicular orientation.
DOI: 10.18150/ld1p95
title: Data related to the work entitled The Adsorption of Chlorpromazine on the Surface of Gold Nanoparticles and Its Effect on the Toxicity to Selected Mammalian Cells

description: This study aimed to synthesize chlorpromazine (CPZ) conjugates with gold nanoparticles (AuNPs) and assess their biological effects on human lymphocyte cell lines (HUT-78 and COLO 720L), as well as human (COLO 679) and murine (B16-F0) melanoma cells. The biological activity of the CPZ-AuNP conjugates was compared to that of free CPZ and well-characterized AuNPs. Cell treatments with CPZ, AuNPs, and CPZ-AuNP conjugates were analyzed using standard assays—MTT, LDH, and MDA—to monitor mitochondrial activity, membrane integrity, and lipid peroxidation, respectively. Results showed that positively charged CPZ-AuNP conjugates were more effective in reducing cell viability than AuNPs alone. A dose-dependent increase in membrane damage was linked to oxidative stress triggered by the conjugates. The biological effects were influenced by both the composition and particle size of the AuNPs. Overall, conjugation with AuNPs appeared to diminish CPZ's biological activity, and the cellular response varied depending on the cell line examined.
DOI: 10.18150/whcdok
title: Data related to the work entitled Spectroscopic Properties and Biological Activity of Fluphenazine Conjugates with Gold Nanoparticles

description: The objective of this study was to develop a method for preparing stable fluphenazine (FPZ) conjugates with gold nanoparticles (AuNPs) and to explore their physicochemical and biological characteristics. The FPZ-AuNP conjugates were synthesized through a ligand exchange reaction on the surface of AuNPs, with an average diameter of 17 ± 5 nm. Electrokinetic analyses showed that the zeta potential of the FPZ-AuNPs was influenced by both their chemical composition and the pH of the surrounding medium. The conjugates exhibited an isoelectric point, attributed to the acid–base behavior of FPZ. To determine the molecular orientation of FPZ upon adsorption, surface-enhanced Raman spectroscopy (SERS) was employed, supported by density functional theory (DFT) calculations. Biological evaluation using human neuroblastoma SH-SY5Y cells demonstrated that FPZ-AuNP conjugates significantly decreased cell viability compared to either free FPZ or citrate-stabilized AuNPs alone. The observed cytotoxic effect was dose-dependent, increasing with higher concentrations of the FPZ-AuNP conjugates.
DOI: 10.15468/dl.k3g3xq
title: Occurrence Download

description: A dataset containing 970 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON((71 33,98 33,98 51,71 51,71 33))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Calligonum L."
 ]
}

 The dataset includes 970 records from 19 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0015869-250426092105405/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.zg3nan
title: Occurrence Download

description: A dataset containing 26692 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Lactarius deterrimus Gröger"
 ]
}

 The dataset includes 26692 records from 229 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0015868-250426092105405/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.53n3zs
title: Occurrence Download

description: A dataset containing 7 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Myrmotherula oreni Miranda, Aleixo, Whitney, Silveira, Guilherme, Santos & Schneider, 2013"
 ]
}

 The dataset includes 7 records from 2 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0015870-250426092105405/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.15342113
title: Immunomodulatory endothelial cells contribute to T cell recruitment and activation through antigen presentation on MHC class II
DOI: 10.5281/zenodo.15342114
title: Immunomodulatory endothelial cells contribute to T cell recruitment and activation through antigen presentation on MHC class II
DOI: 10.5281/zenodo.15342118
title: melanorivulus_kayabi_spades_01.fasta.gz
DOI: 10.5281/zenodo.15342119
title: melanorivulus_kayabi_spades_01.fasta.gz
DOI: 10.48579/pro/mlvpni
title: Occurrence of Cuban bee throughout more than a century (125 years) of data

description: This database contains information on Cuban bees from historical collections of six natural history museums: Museo Nacional de Historia Natural de Cuba, Instituto de Ecología y Sistemática (Havana, Cuba), Muséum national d'Histoire naturelle, American Museum of Natural History, Smithsonian Institution, and the National Museum of Natural History, Washington, Kansas University, Natural History Museum, Kansas from three countries. In addition, it includes information from collections made by the first author between 2018-2024, from the bibliography and online databases, with information from other institutions: Ontario, Toronto, York University, Packer Collection, Florida, Gainesville, Division of Plant Industry, Florida State Collection of Arthropods, Los Angeles County Museum of Natural History, Cornell University Insect Collection, Illinois Natural History Survey, National Museum of Natural History and Museum of Comparative Zoology. The database includes 1322 records, of which 1067 are new records, of bees from various localities in the Cuban provinces of Havana, Mayabeque and Artemisa. Fiftytwo species distributed in 23 genera and 4 families were recorded. For these species, the database provides information on ecology, biogeographic distribution and the museum where the specimens are kept. Coordinates (GPS) from a single point are provided for the 117 localities where species were recorded.
DOI: 10.6084/m9.figshare.28685312
title: Supplementary Material for: Evidence on protective factors for dementia and cognitive impairment in older adults: an umbrella review

description: Introduction: Dementia represents a global public health challenge, and no conclusive evidence exists on how to prevent its onset or at least reduce the risk. This umbrella review aims to identify interventions or exposures that can reduce the incidence of dementia or cognitive impairment.
Methods: A search of meta-analyses and systematic reviews published from 2018 to 2025 (January) was conducted across four databases. Articles assessing associations between interventions or exposures to protective factors and incidence of dementia or cognitive decline in non-demented older adults were selected.
Results: Out of 6,324 articles, 177 underwent full-text screening, and 17 were included. They showed that psychosocial factors (social engagement, purpose in life, life satisfaction, and cognitive reserve) and influenza vaccination protect against dementia. Evidence on antihypertensives is promising, while evidence on low-dose aspirin is promising yet inconclusive. No clear results emerged for both single- and multi-domain lifestyle interventions.
Conclusions: These results offer new insight on potential targets for dementia prevention, a global public health priority. In particular, favorable psychosocial factors and influenza vaccination, undervalued in the scientific debate on dementia prevention, emerged as promising and feasible targets for preventive initiatives. Future research should focus on fine-tuning interventions to promote brain health, exploring their underlying mechanisms, and developing targeted and personalized strategies for specific population subgroups.
DOI: 10.6084/m9.figshare.28685312.v50
title: Supplementary Material for: Evidence on protective factors for dementia and cognitive impairment in older adults: an umbrella review

description: Introduction: Dementia represents a global public health challenge, and no conclusive evidence exists on how to prevent its onset or at least reduce the risk. This umbrella review aims to identify interventions or exposures that can reduce the incidence of dementia or cognitive impairment.
Methods: A search of meta-analyses and systematic reviews published from 2018 to 2025 (January) was conducted across four databases. Articles assessing associations between interventions or exposures to protective factors and incidence of dementia or cognitive decline in non-demented older adults were selected.
Results: Out of 6,324 articles, 177 underwent full-text screening, and 17 were included. They showed that psychosocial factors (social engagement, purpose in life, life satisfaction, and cognitive reserve) and influenza vaccination protect against dementia. Evidence on antihypertensives is promising, while evidence on low-dose aspirin is promising yet inconclusive. No clear results emerged for both single- and multi-domain lifestyle interventions.
Conclusions: These results offer new insight on potential targets for dementia prevention, a global public health priority. In particular, favorable psychosocial factors and influenza vaccination, undervalued in the scientific debate on dementia prevention, emerged as promising and feasible targets for preventive initiatives. Future research should focus on fine-tuning interventions to promote brain health, exploring their underlying mechanisms, and developing targeted and personalized strategies for specific population subgroups.
DOI: 10.6084/m9.figshare.28685312.v49
title: Supplementary Material for: Evidence on protective factors for dementia and cognitive impairment in older adults: an umbrella review

description: Introduction: Dementia represents a global public health challenge, and no conclusive evidence exists on how to prevent its onset or at least reduce the risk. This umbrella review aims to identify interventions or exposures that can reduce the incidence of dementia or cognitive impairment.
Methods: A search of meta-analyses and systematic reviews published from 2018 to 2025 (January) was conducted across four databases. Articles assessing associations between interventions or exposures to protective factors and incidence of dementia or cognitive decline in non-demented older adults were selected.
Results: Out of 6,324 articles, 177 underwent full-text screening, and 17 were included. They showed that psychosocial factors (social engagement, purpose in life, life satisfaction, and cognitive reserve) and influenza vaccination protect against dementia. Evidence on antihypertensives is promising, while evidence on low-dose aspirin is promising yet inconclusive. No clear results emerged for both single- and multi-domain lifestyle interventions.
Conclusions: These results offer new insight on potential targets for dementia prevention, a global public health priority. In particular, favorable psychosocial factors and influenza vaccination, undervalued in the scientific debate on dementia prevention, emerged as promising and feasible targets for preventive initiatives. Future research should focus on fine-tuning interventions to promote brain health, exploring their underlying mechanisms, and developing targeted and personalized strategies for specific population subgroups.
DOI: 10.6084/m9.figshare.28930556
title: Supplementary Material for: Association between Rheumatoid Arthritis and the Incidence of IgA Nephropathy

description: Introduction: IgA nephropathy and rheumatoid arthritis are both common autoimmune diseases, but epidemiological data are limited on the relationship between these two diseases. We aimed to assess the association between rheumatoid arthritis and the risk of developing IgA nephropathy. 
Methods: In this study, we analyzed 4,311,393 adults using a nationwide epidemiological database in Japan. The definitions of rheumatoid arthritis and IgA nephropathy were based on ICD-10 codes. After excluding individuals with a prior history of IgA nephropathy, study participants were categorized into two groups according to the presence of rheumatoid arthritis. The primary outcome was the incidence of IgA nephropathy between January 2005 and May 2022. 
Results: Median (interquartile range) age was 44 (36–53) years, and 2,497,313 (58%) were men. Rheumatoid arthritis was observed in 41,828 individuals (1.0%). During a median follow-up of 1,089 (532–1,797) days, there were 2,610 and 43 incidences of IgA nephropathy in individuals without and with rheumatoid arthritis, yielding incidence rates with 95% confidence intervals of 1.74 (1.67–1.81) and 2.99 (2.22–4.04) per 10,000 person-years, respectively, indicating a higher cumulative incidence in individuals with rheumatoid arthritis (log-rank p= 0.0002). Multivariable Cox regression analysis demonstrated that comorbid rheumatoid arthritis had a higher risk for developing IgA nephropathy (Hazard ratio 1.50, 95% confidence interval 1.10–2.02). Results were consistent even when IgA nephropathy was defined as both the ICD-10 code with the confirmation of performance of kidney biopsy (Hazard ratio 1.70, 95% confidence interval 1.02–2.83).
Conclusion: Our analysis utilizing a largescale population-based cohort concluded that rheumatoid arthritis may increase risk of developing IgA nephropathy.
DOI: 10.6084/m9.figshare.28930562
title: Supplementary Material for: Decoding Precision Aging: The Intersection of Cognitive Decline, Frailty, and Hormonal Biomarkers

description: Background: Cognitive frailty, characterized by the coexistence of cognitive impairment and physical frailty, is a significant predictor of cognitive decline. However, few studies integrate both cognitive and physical assessments alongside hormonal markers, such as cortisol, that may influence frailty and cognitive function. To address this gap, our study combines non-invasive physical, cognitive, and cortisol markers to assess frailty in aging adults.
 
Methods: Data were collected from four sites as part of the Healthy Minds for Life (HML) longitudinal cohort, a project within the Precision Aging Network. Baseline data included cognitive evaluation using the Montreal Cognitive Assessment (MoCA); frailty assessment using a validated 20-second elbow flexion-extension test analyzed by AI under single-task and dual-task conditions; cortisol measurement in eccrine sweat samples via Direct Analysis in Real Time Mass Spectrometry (DART-MS); and demographic information.
 
Results: Of 202 participants completing all assessments, 60 were identified with mild cognitive impairment (MCI). The dual-task frailty index (FI) derived from the 20-second test significantly differentiated individuals with MCI from cognitively robust participants and correlated strongly with MoCA scores (p = 0.015). The dual-task FI showed superior model fit compared to the single-task FI when predicting cognitive function. A significant correlation between the dual-task FI and cortisol by age interaction was observed (p = 0.0042) highlighting the potential impact of cortisol to moderate the relationship between frailty and age in an otherwise healthy aging population. By contrast, no significant correlation was found between dual-task FI and aging outside of the presence of cortisol (p = 0.116) in this study. 

Conclusions: This study highlights practical and efficient methods for assessing frailty emphasizing the value of dual-task testing and cortisol measures in identifying individuals at higher risk for cognitive and physical decline. The findings underscore the importance of integrating hormonal markers with cognitive and physical assessments to enhance risk stratification and intervention planning in aging populations.
DOI: 10.6084/m9.figshare.28930565
title: Supplementary Material for: Association Between Parathyroid Hormone Concentration and Incident Atrial Fibrillation in Older Persons with Kidney Failure Initiating Dialysis

description: Background: Atrial fibrillation (AF) is common in persons with kidney failure on hemodialysis. In the general population, higher intact parathyroid hormone (iPTH) levels were found to be associated with presence of AF. Whether iPTH associates with AF in patients on hemodialysis is unknown.
Methods: Using merged USRDS-DaVita data (2006-2011) we selected persons aged 67+ years who initiated hemodialysis and survived 120 days. Eligible persons had continuous Medicare A+B coverage from 2 years prior to kidney failure and no diagnosis of AF. Sociodemographic, comorbidity, and clinical information was abstracted from Medicare forms, billing claims, and electronic health records. iPTH was categorized consistent with previous work: &lt;150; 150-&lt;300; 300-&lt;600; and 600 pg/mL. Patients were followed for incident (ie, newly-diagnosed) AF as reflected in inpatient and outpatient claims. Unadjusted and multivariable Cox regression was used to estimate the associations of time-updated iPTH category (referent: 150-&lt;300 pg/mL) with incident AF.
Results: Of 15,225 patients initiating hemodialysis, surviving 120 days, and without a prior diagnosis of AF, iPTH (in pg/mL) at baseline was &lt;150 in 4479, 150-&lt;300 in 5964, 300-&lt;600 in 3479, and ≥600 in 1064 persons. During 21,845 patient-years 2857 patients had incident AF (rate, 13.1/100 person-years). After multivariable adjustment, patients with iPTH&lt;150pg/mL had 13% (95% CI, 3-25%) higher relative AF incidence compared with the 150-&lt;300 pg/mL group, but no association was found for those with iPTH 300-&lt;600 (HR: 1.04; 95% CI, 0.95-1.14) or iPTH ≥600 pg/mL (HR: 0.90; 95% CI, 0.75-1.08).
Conclusion: Among persons with incident kidney failure on hemodialysis, compared with those whose iPTH was between 150 and &lt;300 pg/mL, lower iPTH was independently associated with higher AF incidence; however, no association with AF was identified for higher iPTH levels.
DOI: 10.15468/dl.nhqd9z
title: Occurrence Download

description: A dataset containing 30487 species occurrences available in GBIF matching the query:
{
 "and" : [
 "SpeciesKey is one of (Antennaria umbrinella Rydb., Antennaria microphylla Rydb., Antennaria rosea Greene, Antennaria anaphaloides Rydb., Antennaria parvifolia Nutt., Antennaria racemosa Hook., Antennaria corymbosa E.E.Nelson, Antennaria media Greene, Antennaria monocephala DC., Antennaria dimorpha (Nutt.) Torr. & A.Gray, Antennaria howellii Greene, Antennaria neglecta Greene)",
 "HasCoordinate is true"
 ]
}

 The dataset includes 30487 records from 249 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0015871-250426092105405/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.55gfp7
title: Occurrence Download

description: A dataset containing 120338 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Taraba major (Vieillot, 1816)",
 "HasCoordinate is true"
 ]
}

 The dataset includes 120338 records from 185 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0015866-250426092105405/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.usyenb
title: Occurrence Download

description: A dataset containing 849577 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Fagus sylvatica L.",
 "Country is one of (Holy See, Jersey, Guernsey, Isle of Man, United Kingdom of Great Britain and Northern Ireland, Ukraine, Switzerland, Sweden, Spain, Slovakia, Slovenia, Serbia, San Marino, Russian Federation, Romania, Portugal, Poland, Netherlands, Montenegro, Moldova, Republic of, Monaco, Malta, North Macedonia, Luxembourg, Lithuania, Liechtenstein, Latvia, Italy, Ireland, Iceland, Hungary, Greece, Germany, Åland Islands, Finland, Estonia, Faroe Islands, Denmark, Czechia, Croatia, Bulgaria, Bosnia and Herzegovina, Belgium, Belarus, Austria, Andorra, Albania)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 849577 records from 755 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0015867-250426092105405/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.18150/t8abro
title: Raw data for publication "Halloysite supplemented in the diet, and sex of Cherry Valley ducks affects growth, carcass composition, meat quality, and jejunum and leg bone strength"

description: Natural minerals like halloysite may enhance waterfowl nutrition. This study evaluated the effects of 1% halloysite in the diet of male and female Cherry Valley ducks on growth, carcass traits, meat quality, and jejunum and leg bone strength. Ducks were assigned to control and experimental groups (50 birds each), with halloysite added to the experimental group’s diet for 42 days. Halloysite reduced final body weight and weight gain but increased liver weight. Female ducks had more pectoral muscle, total muscle, and abdominal fat, while males had more carcass remains. Treated ducks showed lower protein but higher collagen, fat, and water in pectoral muscles. Control ducks had redder and yellower leg muscles; males had more fat than females. Halloysite increased jejunum strength. Halloysite negatively affected growth but altered meat quality and improved jejunum strength. Its mixed effects suggest further research is needed.The dataset presents raw data related to the publication "Halloysite supplemented in the diet, and sex of Cherry Valley ducks affects growth, carcass composition, meat quality, and jejunum and leg bone strength".The data was obtained as a part of a project entitled "Multiomic research of the gastrointestinal tract and phenotypic features of ducks fed with feed with the addition of aluminosilicates." No. UMO-2021/43/D/NZ9/01756, financed by the National Science Center (Poland). (Project Investigator: Banaszak, Mirosław)This dataset contains data on:- chemical composition of feed;- individual body weight of ducks;- production results for replicates;- tissue composition of carcasses;- meat quality characteristics;- physical characteristics of bones;- physical characteristics of jejunum.