cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.21624438
title: Is Ozone therapy an adjunct treatment for SARS-CoV-2 / COVID-19 infection?

description: Abstract Up to today, there is no specific treatment against SARS-CoV-2 / COVID-19 infection; there the necessity to search for alternatives that help patients with COVID-19. The objective of this study was to review the use of ozone therapy as adjunct treatment for SARS-CoV-2 / COVID-19 infection, highlighting the mechanisms of action, forms of application and current clinical evidence. A systematic review was conducted in electronic databases, searching the terminology Ozone “or” Ozone therapy “and” SARS-CoV-2 or COVID-19 or Coronavirus. Results: nineteen studies were included; ten were editorials, comments, brief reports or reviews, and nine clinical studies. We found that ozone therapy could be favorable for treating patients infected with SARS-CoV-2 / COVID-19, through a direct antiviral effect, regulation of oxidative stress, immunomodulation and improvement of oxygen metabolism. Patients who were treated with ozone therapy responded favorably; therefore, ozone therapy appears to be a promising treatment for patients infected with SARS-CoV-2 / COVID-19. Its mechanism of action justifies its use as an adjuvant therapy; however, scientific evidence is based on case series and clinical trials are necessary to corroborate its effectiveness and safety.
DOI: 10.6084/m9.figshare.21624438.v1
title: Is Ozone therapy an adjunct treatment for SARS-CoV-2 / COVID-19 infection?

description: Abstract Up to today, there is no specific treatment against SARS-CoV-2 / COVID-19 infection; there the necessity to search for alternatives that help patients with COVID-19. The objective of this study was to review the use of ozone therapy as adjunct treatment for SARS-CoV-2 / COVID-19 infection, highlighting the mechanisms of action, forms of application and current clinical evidence. A systematic review was conducted in electronic databases, searching the terminology Ozone “or” Ozone therapy “and” SARS-CoV-2 or COVID-19 or Coronavirus. Results: nineteen studies were included; ten were editorials, comments, brief reports or reviews, and nine clinical studies. We found that ozone therapy could be favorable for treating patients infected with SARS-CoV-2 / COVID-19, through a direct antiviral effect, regulation of oxidative stress, immunomodulation and improvement of oxygen metabolism. Patients who were treated with ozone therapy responded favorably; therefore, ozone therapy appears to be a promising treatment for patients infected with SARS-CoV-2 / COVID-19. Its mechanism of action justifies its use as an adjuvant therapy; however, scientific evidence is based on case series and clinical trials are necessary to corroborate its effectiveness and safety.
DOI: 10.6084/m9.figshare.21624439
title: Relationship between physical activity, feelings of disability, and quality of life in patients with peripheral vestibular dysfunction

description: ABSTRACT Purpose: to verify the association of self-reported feelings of disability and physical activity with the impact of vestibular symptoms on the quality of life of patients with vestibular dysfunction. Methods: a retrospective, cross-sectional, analytical, documentary study approved by the Research Ethics Committee (evaluation report no. 4.462.519), with 50 selected medical records of patients diagnosed with peripheral vestibular dysfunction, including a survey of their medical history and results of the Dizziness Handicap Inventory (DHI). Results: the sample’s mean age was 55.38 years, and the majority were females (70%). The DHI revealed a moderate impact of dizziness. Physically active patients perceived less impact of the disease (p-value = 0.0167), while patients with feelings of disability, due to vestibular symptoms, had a greater damage of their quality of life (p-value = 0.0468). Conclusion: physical activity was associated with less damage of dizziness to the quality of life; also, a greater impact on the quality of life was associated with feelings of disability related to vestibular complaints.
DOI: 10.6084/m9.figshare.21624439.v1
title: Relationship between physical activity, feelings of disability, and quality of life in patients with peripheral vestibular dysfunction

description: ABSTRACT Purpose: to verify the association of self-reported feelings of disability and physical activity with the impact of vestibular symptoms on the quality of life of patients with vestibular dysfunction. Methods: a retrospective, cross-sectional, analytical, documentary study approved by the Research Ethics Committee (evaluation report no. 4.462.519), with 50 selected medical records of patients diagnosed with peripheral vestibular dysfunction, including a survey of their medical history and results of the Dizziness Handicap Inventory (DHI). Results: the sample’s mean age was 55.38 years, and the majority were females (70%). The DHI revealed a moderate impact of dizziness. Physically active patients perceived less impact of the disease (p-value = 0.0167), while patients with feelings of disability, due to vestibular symptoms, had a greater damage of their quality of life (p-value = 0.0468). Conclusion: physical activity was associated with less damage of dizziness to the quality of life; also, a greater impact on the quality of life was associated with feelings of disability related to vestibular complaints.
DOI: 10.6084/m9.figshare.21624441
title: Survival and distribution of weedy rice seedbank after twenty-two years of different rice cropping systems

description: ABSTRACT: Weedy rice (Oryza sativa L.) is the most problematic weed in rice fields due to the few control management alternatives to control it, because of the genetic similarity with the crop. Different cropping systems (regarding soil preparation before sowing) have been used as options to control the persistence and emergence of the weed seedbank. Therefore, the objective of this study was to evaluate the longevity and vertical distribution of weedy rice seeds in the soil seedbank after 22 years of different rice cropping systems. Data was analyzed as a two-way factorial, with cropping systems carried out for 22 years [no-tillage (NT), conventional tillage (CT), wet direct-seeded (WDS)] as one factor and sampling depth (0-2, 2-5, 5-10 and 10-20 cm) as the other factor. The number of whole and deteriorated seeds per m-2 were assessed, as well as the viability (%). No effect between the systems were detected up to 5 cm, however at 5-10 cm CT and WDS showed higher amount of seeds, and WDS at 10-20 cm. As the sampling depth increased, NT showed fewer amount of seeds, while less reduction of the soil seedbank was observed in WDS. CT and WDS spread viable seeds in the soil profile from 0 to 20 cm depth. After 22 years there are viable weedy rice seeds up to 10 cm of depth in the three cropping systems and there is no difference among them up to 5 cm of depth, demonstrating the serious problem of the seedbank for this species.
DOI: 10.6084/m9.figshare.21624441.v1
title: Survival and distribution of weedy rice seedbank after twenty-two years of different rice cropping systems

description: ABSTRACT: Weedy rice (Oryza sativa L.) is the most problematic weed in rice fields due to the few control management alternatives to control it, because of the genetic similarity with the crop. Different cropping systems (regarding soil preparation before sowing) have been used as options to control the persistence and emergence of the weed seedbank. Therefore, the objective of this study was to evaluate the longevity and vertical distribution of weedy rice seeds in the soil seedbank after 22 years of different rice cropping systems. Data was analyzed as a two-way factorial, with cropping systems carried out for 22 years [no-tillage (NT), conventional tillage (CT), wet direct-seeded (WDS)] as one factor and sampling depth (0-2, 2-5, 5-10 and 10-20 cm) as the other factor. The number of whole and deteriorated seeds per m-2 were assessed, as well as the viability (%). No effect between the systems were detected up to 5 cm, however at 5-10 cm CT and WDS showed higher amount of seeds, and WDS at 10-20 cm. As the sampling depth increased, NT showed fewer amount of seeds, while less reduction of the soil seedbank was observed in WDS. CT and WDS spread viable seeds in the soil profile from 0 to 20 cm depth. After 22 years there are viable weedy rice seeds up to 10 cm of depth in the three cropping systems and there is no difference among them up to 5 cm of depth, demonstrating the serious problem of the seedbank for this species.
DOI: 10.6084/m9.figshare.21624442
title: Abnormal Origin of the Pulmonary Artery from the Ascending Aorta in the Neonate

description: ABSTRACT The anomalous origin of one pulmonary artery from the ascending aorta is a rare congenital heart disease, generally diagnosed based on the clinical information and on echocardiographic and computed tomography angiography findings. Here we report two neonates successfully treated with surgery early in life.
DOI: 10.6084/m9.figshare.21624442.v1
title: Abnormal Origin of the Pulmonary Artery from the Ascending Aorta in the Neonate

description: ABSTRACT The anomalous origin of one pulmonary artery from the ascending aorta is a rare congenital heart disease, generally diagnosed based on the clinical information and on echocardiographic and computed tomography angiography findings. Here we report two neonates successfully treated with surgery early in life.
DOI: 10.6084/m9.figshare.21624445
title: Nile tilapia nursery feeding management in a biofloc system

description: ABSTRACT Nile tilapia (Oreochromis niloticus) has an opportunistic omnivorous feeding behavior and studies have demonstrated the consumption of microorganisms by the species from bioflocs, especially in the early phases of life. One may thus assume that when reared in biofloc systems, there may be a reduction in the feeding rates in the Nile tilapia nursery system when compared to the ponds. This study evaluated the effects of different feeding management options in Nile tilapia nurseries in a biofloc system. A total of 700 fingerlings (2.37 ± 0.55 g) were stocked in 20 experimental units (100 L) and inoculated with mature biofloc for the evaluation of five different feeding management options. After 49 days, it was observed that the higher feed rates caused an increase in nitrogen compounds and solids in the water, worsening the feed conversion rate. Furthermore, the excess feed supplied to the tilapia in the biofloc caused a reduction in the utilization of protein nitrogen, an increase in the liver and visceral fat, in addition to an increase in the production of solids and consumption of alkalinizer by fish biomass. On the other hand, low feeding rates cause a decrease in the growth and uniformity of the tilapia juveniles. Taking the results into consideration, it is recommended to use the feed management option proposed in treatment TC (26% below the highest feed rate) in the tilapia nursery in the biofloc system.
DOI: 10.6084/m9.figshare.21624445.v1
title: Nile tilapia nursery feeding management in a biofloc system

description: ABSTRACT Nile tilapia (Oreochromis niloticus) has an opportunistic omnivorous feeding behavior and studies have demonstrated the consumption of microorganisms by the species from bioflocs, especially in the early phases of life. One may thus assume that when reared in biofloc systems, there may be a reduction in the feeding rates in the Nile tilapia nursery system when compared to the ponds. This study evaluated the effects of different feeding management options in Nile tilapia nurseries in a biofloc system. A total of 700 fingerlings (2.37 ± 0.55 g) were stocked in 20 experimental units (100 L) and inoculated with mature biofloc for the evaluation of five different feeding management options. After 49 days, it was observed that the higher feed rates caused an increase in nitrogen compounds and solids in the water, worsening the feed conversion rate. Furthermore, the excess feed supplied to the tilapia in the biofloc caused a reduction in the utilization of protein nitrogen, an increase in the liver and visceral fat, in addition to an increase in the production of solids and consumption of alkalinizer by fish biomass. On the other hand, low feeding rates cause a decrease in the growth and uniformity of the tilapia juveniles. Taking the results into consideration, it is recommended to use the feed management option proposed in treatment TC (26% below the highest feed rate) in the tilapia nursery in the biofloc system.
DOI: 10.6084/m9.figshare.21624447.v1
title: Analysis of muscle activation in children and adolescents with severe cerebral palsy

description: Abstract Introduction: Children and adolescents with spastic quadriparesis have a worse selective motor control, and studies with this population are still very scarce. The same is true with scientific evidence of one of the methods most used as a physiotherapeutic treatment in this population, the Bobath Concept. Objective: To evaluate spine erector muscles activation, gluteus medius and gluteus maximus, through the handling of the Bobath Concept and the sustained kneeling posture in subjects with a diagnosis of severe cerebral palsy; and to compare muscle activation with a reference group, in order to increase the reliability of this study. Methods: A cross-sectional study was carried out with 38 children and adolescents with cerebral palsy, classified by GMFCS at levels IV and V, and 20 healthy participants, aged between 3 and 18 years. They were submitted to the handling of the Bobath Concept and to the sustained kneeling posture, with muscle activation obtained by electromyography. Results: We observed significant muscle activation during handling in side-sitting, with weight transfer and without the help of another therapist, and in the sustained kneeling posture, for the erector of the spine and gluteus medius. Conclusion: The evidence from this study suggests that both the handling in side-sitting and the sustained kneeling posture cause significant muscle activation in the erector of the spine and gluteus medius for severe quadriparesis subjects, GMFCS IV and V, which can contribute to the improvement of postural control and decision-making in physical therapy practice.
DOI: 10.6084/m9.figshare.21624447
title: Analysis of muscle activation in children and adolescents with severe cerebral palsy

description: Abstract Introduction: Children and adolescents with spastic quadriparesis have a worse selective motor control, and studies with this population are still very scarce. The same is true with scientific evidence of one of the methods most used as a physiotherapeutic treatment in this population, the Bobath Concept. Objective: To evaluate spine erector muscles activation, gluteus medius and gluteus maximus, through the handling of the Bobath Concept and the sustained kneeling posture in subjects with a diagnosis of severe cerebral palsy; and to compare muscle activation with a reference group, in order to increase the reliability of this study. Methods: A cross-sectional study was carried out with 38 children and adolescents with cerebral palsy, classified by GMFCS at levels IV and V, and 20 healthy participants, aged between 3 and 18 years. They were submitted to the handling of the Bobath Concept and to the sustained kneeling posture, with muscle activation obtained by electromyography. Results: We observed significant muscle activation during handling in side-sitting, with weight transfer and without the help of another therapist, and in the sustained kneeling posture, for the erector of the spine and gluteus medius. Conclusion: The evidence from this study suggests that both the handling in side-sitting and the sustained kneeling posture cause significant muscle activation in the erector of the spine and gluteus medius for severe quadriparesis subjects, GMFCS IV and V, which can contribute to the improvement of postural control and decision-making in physical therapy practice.
DOI: 10.6084/m9.figshare.21382717
title: A typical enzyme activity for glutathione conjugation indicates exposure of pacu to pollutants

description: Abstract Functional enzyme assays to detect sublethal poisoning of Neotropical fish are paramount. Accordingly, we assayed a glutathione S-transferase (GST) activity in liver and kidney cytosols from Piaractus mesopotamicus injected with methyl parathion or benzo[a]pyrene using the substrate 1-chloro-2,4-dinitrobenzene (CDNB), which is the usual substrate for assaying a known general activity of GST. Since the most reactive substrate is required to reveal specific changes in enzyme activity, we also used two alternative substrates, 1,2-dichloro-4-nitrobenzene (DCNB) and ethacrynic acid (ETHA). Activities with CDNB or ETHA did not change. However, assays with DCNB showed that methyl parathion caused a decrease in GST activity in the liver on the 24th, 48th and 96th hour after the injection. DCNB also revealed that GST activity in the liver increased seven days after benzo[a]pyrene injection, coming down to normal after fourteen days. Benzo[a]pyrene, but not methyl parathion, increased the activities with DCNB in cytosol from the kidney seven and fourteen days after the injection. Thus, a decreased liver GST activity assayed with DCNB corresponded to contamination of P. mesopotamicus with methyl parathion. The increase of this GST activity in the liver and the kidney correlates to pacu contamination with polycyclic aromatic hydrocarbons.
DOI: 10.6084/m9.figshare.21382717.v1
title: A typical enzyme activity for glutathione conjugation indicates exposure of pacu to pollutants

description: Abstract Functional enzyme assays to detect sublethal poisoning of Neotropical fish are paramount. Accordingly, we assayed a glutathione S-transferase (GST) activity in liver and kidney cytosols from Piaractus mesopotamicus injected with methyl parathion or benzo[a]pyrene using the substrate 1-chloro-2,4-dinitrobenzene (CDNB), which is the usual substrate for assaying a known general activity of GST. Since the most reactive substrate is required to reveal specific changes in enzyme activity, we also used two alternative substrates, 1,2-dichloro-4-nitrobenzene (DCNB) and ethacrynic acid (ETHA). Activities with CDNB or ETHA did not change. However, assays with DCNB showed that methyl parathion caused a decrease in GST activity in the liver on the 24th, 48th and 96th hour after the injection. DCNB also revealed that GST activity in the liver increased seven days after benzo[a]pyrene injection, coming down to normal after fourteen days. Benzo[a]pyrene, but not methyl parathion, increased the activities with DCNB in cytosol from the kidney seven and fourteen days after the injection. Thus, a decreased liver GST activity assayed with DCNB corresponded to contamination of P. mesopotamicus with methyl parathion. The increase of this GST activity in the liver and the kidney correlates to pacu contamination with polycyclic aromatic hydrocarbons.
DOI: 10.6084/m9.figshare.21624451
title: Industry workers with hypertension and diabetes mellitus, the prevalence of self-reported adherence, and disease control

description: Abstract To evaluate the prevalence of self-reported drug adherence and factors associated, as well as clinical health outcomes, for industry workers with hypertension (HTN) and diabetes mellitus (DM). This was a cross-sectional study of 137 Brazilian industry workers with HTN and/ or DM. Self-reported adherence was assessed, and the disease control was defined through blood pressure and capillary glycemia values. Data were descriptively analyzed and the factors associated with adherence were evaluated using the Poisson model with robust variance to calculate prevalence ratios. The prevalence of self-reported drug adherence was 79.6% and the prevalence of disease control was 53.8%. There was no statistically significant association between the two variables. In the controlled disease group, non-adherence was associated with being under 40 years of age, not having a partner, and having a risky alcohol consumption habit. In the uncontrolled disease group, adherence was highest for participants aged 40 years and older. The prevalence of self-reported drug adherence was high, but the prevalence of disease control was low and not associated with adherence, indicating that the self-reported adherence measure may be inaccurate. Our findings identify some factors that explain non-adherent behavior in the workforce.
DOI: 10.6084/m9.figshare.21624451.v1
title: Industry workers with hypertension and diabetes mellitus, the prevalence of self-reported adherence, and disease control

description: Abstract To evaluate the prevalence of self-reported drug adherence and factors associated, as well as clinical health outcomes, for industry workers with hypertension (HTN) and diabetes mellitus (DM). This was a cross-sectional study of 137 Brazilian industry workers with HTN and/ or DM. Self-reported adherence was assessed, and the disease control was defined through blood pressure and capillary glycemia values. Data were descriptively analyzed and the factors associated with adherence were evaluated using the Poisson model with robust variance to calculate prevalence ratios. The prevalence of self-reported drug adherence was 79.6% and the prevalence of disease control was 53.8%. There was no statistically significant association between the two variables. In the controlled disease group, non-adherence was associated with being under 40 years of age, not having a partner, and having a risky alcohol consumption habit. In the uncontrolled disease group, adherence was highest for participants aged 40 years and older. The prevalence of self-reported drug adherence was high, but the prevalence of disease control was low and not associated with adherence, indicating that the self-reported adherence measure may be inaccurate. Our findings identify some factors that explain non-adherent behavior in the workforce.
DOI: 10.6084/m9.figshare.21624454
title: Rhizosphere bacterial and fungal communities of healthy and wilted pepper (Capsicum annuum L.) in an organic farming system

description: ABSTRACT: Rhizosphere microorganisms play an important role in the growth and health of plants. Around the world, diverse soil-borne pathogens attack Capsicum annuum causing significant damage and economic losses. This study determined whether the diversity and composition of microbial communities in the rhizosphere soil of C. annuum plants is significantly changed by wilt disease. We used the 16S rRNA gene for bacteria and the internal transcribed spacer region for fungi to characterize the rhizosphere microbiomes of healthy and wilted plants. The most abundant bacterial phyla were Proteobacteria and Gemmatimonadetes, while the most abundant fungal phyla were Ascomycota and Mucoromycota. The bacterial α-diversity did not show significant differences in richness and diversity, but did show a significant difference in evenness and dominance of species. Rare taxa were present in both healthy and wilted conditions with relative abundances &lt; 1%. In the fungi, all evaluated estimators showed a significant reduction in the wilted condition. The β-diversity showed significant differences in the structure of bacterial and fungal communities, which were segregated according to plant health conditions. The same occurred when comparing the alpha and beta diversity of this study based on organic agriculture with that of other studies based on conventional agriculture. We observed a significant difference with estimators analyzed by segregating rhizosphere communities depending on the farming method used. Finally, the differential abundance analysis did not show significant results in the bacterial communities; however, in the fungal communities, Fusarium, Thanatephorus, Rhizopus, Curvularia, Cladosporium, and Alternaria were more abundant in the rhizosphere of wilted than healthy plants. Species from these genera have been previously reported as phytopathogens of several plants, including C. annuum.