cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.10800971
title: Genetic architecture of immune cell DNA methylation in the rhesus macaque

description: Complete model outputs from rhesus macaque (Macaca mulatta) whole blood meQTL and eQTL analyses in article, "Genetic architecture of immune cell DNA methylation in the rhesus macaque". 

cis meQTL model output (SNP-CpG associations): 



IMAGE_573_meqtl_model_res_wPVE.txt: 



Model results from IMAGE meQTL mapping including all genome, chromatin state annotations, and PVE estimates



pqlseq_allimagesnps_res_converged_wpve.txt:



Model results from PQLseq meQTL mapping including PVE estimates 




cis eQTL model output (SNP-gene associations): 



eqtl_res_sva5_gemma_172samples_qvalue.txt: 



Model results from GEMMA eQTL mapping
DOI: 10.5281/zenodo.10800972
title: Genetic architecture of immune cell DNA methylation in the rhesus macaque

description: Complete model outputs from rhesus macaque (Macaca mulatta) whole blood meQTL and eQTL analyses in article, "Genetic architecture of immune cell DNA methylation in the rhesus macaque". 

cis meQTL model output (SNP-CpG associations): 



IMAGE_573_meqtl_model_res_wPVE.txt: 



Model results from IMAGE meQTL mapping including all genome, chromatin state annotations, and PVE estimates



pqlseq_allimagesnps_res_converged_wpve.txt:



Model results from PQLseq meQTL mapping including PVE estimates 




cis eQTL model output (SNP-gene associations): 



eqtl_res_sva5_gemma_172samples_qvalue.txt: 



Model results from GEMMA eQTL mapping
DOI: 10.26179/anef-0h92
title: Aurora Australis Voyage 1 2004-2005 Underway Data
DOI: 10.6084/m9.figshare.25388524
title: Supplementary Material for Partitioning of tin between mafic minerals, Fe-Ti oxides and silicate melts: Implications for tin enrichment in magmatic processes

description: Supplementary Material for Partitioning of tin between mafic minerals, Fe-Ti oxides and silicate melts: Implications for tin enrichment in magmatic processes
DOI: 10.34740/kaggle/dsv/7820576
title: Layline Shareholder activism dataset
DOI: 10.26179/cayn-1052
title: Aurora Australis Voyage 2 2004-2005 Underway Data
DOI: 10.26179/fdae-fx94
title: Aurora Australis Voyage 3 2004-2005 Underway Data
DOI: 10.18112/openneuro.ds005025.v1.1.0
title: Traveling Spine 7T CoilQA
DOI: 10.7910/dvn/8qqk6j
title: Attrition and the Gender Patenting Gap

description: Review of Economics and Statistics: Forthcoming.
DOI: 10.5281/zenodo.1422845
title: Observations of Diurnal Coastal-Trapped Waves with a Thermocline-Intensified Velocity Field

description: Repository for the data presented in the JPO 2019 article: "Observations of Diurnal Coastal-Trapped Waves with a Thermocline-Intensified Velocity Field". Observations were compared against output from Ken Brink's model. The model is available from: https://darchive.mblwhoilibrary.org/handle/1912/10527.
DOI: 10.6084/m9.figshare.25388452.v1
title: maximum_likelihood_trees

description: IQ-Tree output files (log, iqtree, and tree files) for maximum likelihood tree estimation for 14 empirical phylogenetic datasets.
DOI: 10.5517/ccdc.csd.cc2dcbpt
title: CCDC 2215436: Experimental Crystal Structure Determination

description: Related Article: Nikita R. Romanenko, Maxim A. Faraonov, Nikita G. Osipov, Alexey V. Kuzmin, Salavat S. Khasanov, Akihiro Otsuka, Hideki Yamochi, Hiroshi Kitagawa, Dmitri V. Konarev|2023|New J.Chem.|47|6924|doi:10.1039/D3NJ00506B
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2dps52
title: CCDC 2225464: Experimental Crystal Structure Determination

description: Related Article: Shi-Yi Liu, Xue-Xin Li, Wei-Chao Chen, Kui-Zhan Shao, Xin-Long Wang, Chao Qin, Zhong-Min Su|2023|Sci.China.Chem.|67|862|doi:10.1007/s11426-023-1776-0
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.6084/m9.figshare.25389187
title: Supplementary Material for: MiR-21-5p modulates airway inflammation and epithelial-mesenchymal transition processes in a mouse model of CARAS

description: Introduction: Combined allergic rhinitis and asthma syndrome (CARAS) is a concurrent allergic symptom of diseases of allergic rhinitis and asthma. However, the mechanism of CARAS remains unclear. The study aimed to investigate the impact of microRNA-21 (miR-21) on CARAS via targeting Poly (ADP-ribose) polymerase-1 (PARP-1) and PI3K/AKT pathways.
Methods: The levels of miR-21-5p and PARP-1 in CARAS patients were detected by Quantitative reverse transcription polymerase chain reaction (RT-qPCR) and Enzyme-linked Immunosorbent Assay (ELISA). An ovalbumin (OVA)-sensitized mouse model of CARAS was established. And knock down of miR-21-5p was constructed by intranasally administering with miR-21-5p shRNA-encoding adeno-associated virus (AAV) vector. Airway resistance and airway inflammatory response were detected. ELISA was used to evaluate IL-4/IL-5/IL-13 levels in bronchoalveolar lavage fluid (BALF). Expression levels of E-cadherin, fibronectin, and α-SMA were determined using western blotting. The levels of PARP-1 and the activation of PI3K/AKT were assayed.
Results: Down-regulation of miR-21-5p relieved pathophysiological symptoms of asthma including airway hyperreactivity and inflammatory cell infiltration. Down-regulation of miR-21-5p significantly reduced the levels of IL4, IL-5, and IL-13 in BALF. Additionally, down-regulation of miR-21-5p inhibited the epithelial-mesenchymal transition (EMT) process in CARAS mice. Furthermore, miR-21-5p regulated PARP-1 and was involved in PI3K/AKT activation in CARAS mice.
Conclusion: Down-regulation of miR-21-5p ameliorated CARAS-associated lung injury by alleviating airway inflammation, inhibiting the EMT process and regulating PARP-1/PI3K/AKT in a mouse model of CARAS.
DOI: 10.48479/7zn6-bw59
title: Tidally offset neutral gas in Lyman continuum emitting galaxy Haro 11

description: Around 400 million years after the Big Bang, the ultraviolet emission from star-forming galaxies reionized the Universe. Ionizing
radiation (Lyman Continuum, LyC) is absorbed by cold neutral hydrogen gas (Hi) within galaxies, hindering the escape of LyC
photons. Since the Hi reservoir of LyC emitters has never been mapped, major uncertainties remain on how LyC photons escape
galaxies and ionize the intergalactic medium. We have directly imaged the neutral gas in the nearby reionization-era analog
galaxy Haro 11 with the 21cm line to identify the mechanism enabling ionizing radiation escape. We find that merger-driven
interactions have caused a bulk offset of the neutral gas by about 6 kpc from the center of the galaxy, where LyC emission
production sites are located. This could facilitate the escape of ionizing radiation into our line of sight. Galaxy interactions can
cause both elevated LyC production and large-scale displacement of Hi from the regions where these photons are produced.
They could contribute to the anisotropic escape of LyC radiation from galaxies and the reionization of the Universe. We argue
for a systematic assessment of the effect of environment on LyC production and escape.
DOI: 10.5281/zenodo.10807048
title: Iranian Sheep Genotypes
DOI: 10.5281/zenodo.10807049
title: Iranian Sheep Genotypes
DOI: 10.6084/m9.figshare.25388260.v1
title: 01.原始数据

description: Eggplant transcriptome data
DOI: 10.26036/cnp0005248
title: Dasiphora genome resequencing data

description: Dasiphora genome resequencing data
DOI: 10.6084/m9.figshare.24499003
title: <b>An outsized contribution of rivers to carbon emissions from interconnected urban river-lake networks within plains</b>

description: This study explored the patterns of carbon dioxide (CO<sub>2</sub>) and methane (CH<sub>4</sub>) emissions and underlying mechanisms in Ge Lake and its tributaries, located in an urban area within a plain in China. The results revealed that carbon emissions from rivers were significantly higher than those from the downstream receiving lake, exhibiting a decrease along the river flow direction. The findings may add the understanding carbon emissions in plain aquatic ecosystems, and benefit the estimates of carbon emissions in these regions with greater precision.
DOI: 10.6084/m9.figshare.24499003.v2
title: <b>An outsized contribution of rivers to carbon emissions from interconnected urban river-lake networks within plains</b>

description: This study explored the patterns of carbon dioxide (CO<sub>2</sub>) and methane (CH<sub>4</sub>) emissions and underlying mechanisms in Ge Lake and its tributaries, located in an urban area within a plain in China. The results revealed that carbon emissions from rivers were significantly higher than those from the downstream receiving lake, exhibiting a decrease along the river flow direction. The findings may add the understanding carbon emissions in plain aquatic ecosystems, and benefit the estimates of carbon emissions in these regions with greater precision.
DOI: 10.6084/m9.figshare.24499003.v1
title: <b>An outsized contribution of rivers to carbon emissions from urban aquatic ecosystems in plains</b>

description: This study explored the patterns of carbon dioxide (CO<sub>2</sub>) and methane (CH<sub>4</sub>) emissions and underlying mechanisms in Ge Lake and its tributaries, located in an urban area within a plain in China. The results revealed that carbon emissions from rivers were significantly higher than those from the downstream receiving lake, exhibiting a decrease along the river flow direction. The findings may add the understanding carbon emissions in plain aquatic ecosystems, and benefit the estimates of carbon emissions in these regions with greater precision.
DOI: 10.5281/zenodo.10807024
title: Data & Code of "A new function of offset response in the primate auditory cortex: marker of temporal integration"
DOI: 10.5281/zenodo.10807023
title: Data & Code of "A new function of offset response in the primate auditory cortex: marker of temporal integration"
DOI: 10.6084/m9.figshare.23672355.v1
title: Data for "Matching the scales of planning and environmental risk: An evaluation of Community Wildfire Protection Plans in the western U.S."

description: Data for "Matching the scales of planning and environmental risk: An evaluation of Community Wildfire Protection Plans in the western U.S."
DOI: 10.6084/m9.figshare.25389856
title: RAWDATA-<b>Renal tissue-derived exosomal miRNA-34a in diabetic nephropathy induces renal tubular cell fibrosis by promoting the polarization of M1 macrophages</b>

description: <b>Background:</b> Diabetic nephropathy (DN) is the leading cause of chronic kidney disease, and the activation and infiltration of phagocytes are critical steps of DN. This study aimed to explore the mechanism of exosomes in macrophages and diabetes nephropathy and the role of miRNA-34a, which might provide a new path for treating DN.<b>Methods:</b> The DN model was established, and the success of the model establishment was confirmed by detecting general indicators, HE staining, and immunohistochemistry. Electron microscopy and NanoSight Tracking Analysis (NTA) were used to see the morphology and size of exosomes. MiRNA-34a inhibitor, miRNA-34a mimics, pc-PPARGC1A, and controls were transfected in macrophages with or without kidney exosomal. A dual luciferase reporter gene experiment verifies the targeting relationship between miRNA-34a and PPARGC1A. After exosomal culture, macrophages are co-cultured with normal renal tubular cells to detect renal tubular cell fibrosis. Q-PCR and western blot were undertaken to detect related RNA and proteins.<b>Results: </b>An animal model of diabetic nephropathy was successfully constructed. Macrophages could phagocytose exosomes. After ingesting model exosomes, M1 macrophages were activated, while M2 macrophages were weakened, indicating the model mice's kidney exosomes caused the polarization. MiRNA-34a inhibitor increased PPARGC1A expression. MiRNA-34a expressed higher in diabetic nephropathy model-Exo. MiRNA-34a negatively regulated PPARGC1A. <i>PPARGC1A</i> rescued macrophage polarization and renal tubular cell fibrosis.<b>Conclusion:</b> Exosomal miRNA-34a of tubular epithelial cells promoted M1 macrophage activation in diabetic nephropathy via negatively regulating PPARGC1A expression, which may provide a new direction for further exploration of DN treatment.
DOI: 10.6084/m9.figshare.25389856.v1
title: RAWDATA-<b>Renal tissue-derived exosomal miRNA-34a in diabetic nephropathy induces renal tubular cell fibrosis by promoting the polarization of M1 macrophages</b>

description: <b>Background:</b> Diabetic nephropathy (DN) is the leading cause of chronic kidney disease, and the activation and infiltration of phagocytes are critical steps of DN. This study aimed to explore the mechanism of exosomes in macrophages and diabetes nephropathy and the role of miRNA-34a, which might provide a new path for treating DN.<b>Methods:</b> The DN model was established, and the success of the model establishment was confirmed by detecting general indicators, HE staining, and immunohistochemistry. Electron microscopy and NanoSight Tracking Analysis (NTA) were used to see the morphology and size of exosomes. MiRNA-34a inhibitor, miRNA-34a mimics, pc-PPARGC1A, and controls were transfected in macrophages with or without kidney exosomal. A dual luciferase reporter gene experiment verifies the targeting relationship between miRNA-34a and PPARGC1A. After exosomal culture, macrophages are co-cultured with normal renal tubular cells to detect renal tubular cell fibrosis. Q-PCR and western blot were undertaken to detect related RNA and proteins.<b>Results: </b>An animal model of diabetic nephropathy was successfully constructed. Macrophages could phagocytose exosomes. After ingesting model exosomes, M1 macrophages were activated, while M2 macrophages were weakened, indicating the model mice's kidney exosomes caused the polarization. MiRNA-34a inhibitor increased PPARGC1A expression. MiRNA-34a expressed higher in diabetic nephropathy model-Exo. MiRNA-34a negatively regulated PPARGC1A. <i>PPARGC1A</i> rescued macrophage polarization and renal tubular cell fibrosis.<b>Conclusion:</b> Exosomal miRNA-34a of tubular epithelial cells promoted M1 macrophage activation in diabetic nephropathy via negatively regulating PPARGC1A expression, which may provide a new direction for further exploration of DN treatment.
DOI: 10.6084/m9.figshare.25388260.v2
title: 01.原始数据

description: 茄子转录组数据
DOI: 10.5281/zenodo.6111983
title: Earthquake catalogue for the Taupō region: 2010–2019

description: This deposit contains the earthquake catalogue described in "A Decade of Earthquake Activity at Taupō Volcano, New Zealand" by Illsley-Kemp et al., submitted for publication in <em>Volcanica.</em> Events that have been identified as false detections, caused by distance large magnitude earthquakes are flagged by event_type='other event'
DOI: 10.5281/zenodo.6832537
title: Earthquake catalogue for the Taupō region: 2010–2019

description: This deposit contains the earthquake catalogue described in "A Decade of Earthquake Activity at Taupō Volcano, New Zealand" by Illsley-Kemp et al., published in <em>Volcanica: </em>https://doi.org/10.30909/vol.05.02.335348 If you use this dataset please cite this paper appropriately Events that have been identified as false detections, caused by distance large magnitude earthquakes are flagged by event_type='other event'
DOI: 10.5281/zenodo.7882274
title: Earthquake catalogue for the Taupō region: 2010–2019

description: This deposit contains the earthquake catalogue described in "A Decade of Earthquake Activity at Taupō Volcano, New Zealand" by Illsley-Kemp et al., published in Volcanica: https://doi.org/10.30909/vol.05.02.335348


If you use this dataset please cite this paper appropriately


Events that have been identified as false detections, caused by distance large magnitude earthquakes are flagged by event_type='other event'
DOI: 10.6084/m9.figshare.25389430
title: Additional file 1 of Annual dialysis data report 2020, JSDT renal data registry

description: Additional file 1. Supplementary tables 1–42.
DOI: 10.15156/bio/sh3566876.08fu
title: SH3566876.08FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15156/bio/sh3566877.08fu
title: SH3566877.08FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15156/bio/sh3566878.08fu
title: SH3566878.08FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.25549/one-c4-6739
title: ONE magazine 2/1 (1954-01)

description: ONE magazine, volume 2, number 1 (1954 January). Issued monthly.
DOI: 10.15156/bio/sh1567635.08fu
title: SH1567635.08FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15156/bio/sh1567636.08fu
title: SH1567636.08FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15156/bio/sh1567637.08fu
title: SH1567637.08FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.