cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.23677785.v1
title: Jamestown Canyon Virus is transmissible by <em>Aedes aegypti</em> and is only moderately blocked by <em>Wolbachia</em> co-infection

description: Jamestown Canyon virus (JCV), a negative-sense arbovirus, is increasingly common in the upper Midwest of the USA. Transmitted by a range of mosquito genera, JCV’s primary amplifying host is white-tailed deer. <i>Aedes aegypti</i> is responsible for transmitting various positive-sense viruses globally including dengue (DENV), Zika, chikungunya, and Yellow Fever. <i>Ae. aegypti’s </i>distribution, once confined to the tropics, is expanding, in part due to climate change. <i>Wolbachia</i>, an insect endosymbiont, limits the replication of co-infecting viruses inside insects. The release and spread of the symbiont into <i>Ae. aegypti</i> populations have been effective in reducing transmission of DENV to humans, although the mechanism of <i>Wolbachia</i>-mediated viral blocking is still poorly understood. Here we explored JCV infection potential in <i>Ae. aegypti</i>, the nature of the vector’s immune response, and interactions with <i>Wolbachia</i> infection. We show that <i>Ae. aegypti</i> is highly competent for JCV, which grows to high loads and rapidly reaches the saliva after an infectious blood meal. The mosquito immune system responds with strong induction of RNAi and JAK/STAT. Neither the direct effect of viral infection nor the energetic investment in immunity appears to affect mosquito longevity. <i>Wolbachia</i> infection blocked JCV only in the early stages of infection. <i>Wolbachia</i>-induced immunity was small compared to that of JCV, suggesting innate immune priming does not likely explain blocking. We propose two models to explain why <i>Wolbachia’s </i>blocking of negative-sense viruses like JCV may be less than that of positive-sense viruses, relating to the slowdown of host protein synthesis and the triggering of interferon-like factors like Vago. In conclusion, we highlight the risk for increased human disease with the predicted future overlap of <i>Ae. aegypti</i> and JCV ranges. We suggest that with moderate <i>Wolbachia</i>-mediated blocking and distinct biology, negative-sense viruses represent a fruitful comparator model to other viruses for understanding blocking mechanisms in mosquitoes.<br>
DOI: 10.6084/m9.figshare.23677785
title: Jamestown Canyon Virus is transmissible by <em>Aedes aegypti</em> and is only moderately blocked by <em>Wolbachia</em> co-infection

description: Jamestown Canyon virus (JCV), a negative-sense arbovirus, is increasingly common in the upper Midwest of the USA. Transmitted by a range of mosquito genera, JCV’s primary amplifying host is white-tailed deer. <i>Aedes aegypti</i> is responsible for transmitting various positive-sense viruses globally including dengue (DENV), Zika, chikungunya, and Yellow Fever. <i>Ae. aegypti’s </i>distribution, once confined to the tropics, is expanding, in part due to climate change. <i>Wolbachia</i>, an insect endosymbiont, limits the replication of co-infecting viruses inside insects. The release and spread of the symbiont into <i>Ae. aegypti</i> populations have been effective in reducing transmission of DENV to humans, although the mechanism of <i>Wolbachia</i>-mediated viral blocking is still poorly understood. Here we explored JCV infection potential in <i>Ae. aegypti</i>, the nature of the vector’s immune response, and interactions with <i>Wolbachia</i> infection. We show that <i>Ae. aegypti</i> is highly competent for JCV, which grows to high loads and rapidly reaches the saliva after an infectious blood meal. The mosquito immune system responds with strong induction of RNAi and JAK/STAT. Neither the direct effect of viral infection nor the energetic investment in immunity appears to affect mosquito longevity. <i>Wolbachia</i> infection blocked JCV only in the early stages of infection. <i>Wolbachia</i>-induced immunity was small compared to that of JCV, suggesting innate immune priming does not likely explain blocking. We propose two models to explain why <i>Wolbachia’s </i>blocking of negative-sense viruses like JCV may be less than that of positive-sense viruses, relating to the slowdown of host protein synthesis and the triggering of interferon-like factors like Vago. In conclusion, we highlight the risk for increased human disease with the predicted future overlap of <i>Ae. aegypti</i> and JCV ranges. We suggest that with moderate <i>Wolbachia</i>-mediated blocking and distinct biology, negative-sense viruses represent a fruitful comparator model to other viruses for understanding blocking mechanisms in mosquitoes.<br>
DOI: 10.34740/kaggle/dsv/6364211
title: PV Power UV Illuminance Temperature Humidity
DOI: 10.34740/kaggle/dsv/6364470
title: MoviesDatasets
DOI: 10.34740/kaggle/dsv/6364489
title: Mahanagar Yatayat Transport Dataset
DOI: 10.3886/e117405v1-141121
title: Data and code for: Bartik Instruments: What, When, Why, and How

description: This repository contains code and data associated with our paper title "Bartik Instruments: What, When, Why, and How." The abstract of the paper is: The Bartik instrument is formed by interacting local industry shares and national industry growth rates. We show that the typical use of a Bartik instrument assumes a pooled exposure research design, where the shares measure differential exposure to common shocks, and identification is based on exogeneity of the shares. Next, we show how the Bartik instrument weights each of the exposure designs. Finally, we discuss how to assess the plausibility of the research design. We illustrate our results through two applications: estimating the elasticity of labor supply, and estimating the elasticity of substitution between immigrants and natives.
DOI: 10.48511/hnag-sf78
title: Indian Lake Level

description: This dataset contains lake level data for Indian Lake level logger. This site is part of the Living Lakes Canada Columbia Basin Water Monitoring Framework program. Indian Lake was selected for monitoring because it was identified as a priority by the Yaq̓it ʔa·knuqⱡi ‘it. The data is being collected to track the impacts of climate change on Columbia Basin water supply and support community climate adaptation. Monitoring has been implemented on this site. Data will be added soon.

Province of BC, Healthy Watersheds Initiative partners (Stronger BC, Real Estate Foundation of BC, Watersheds BC), Province of BC, Columbia Basin Trust, Canada’s Digital Technology Supercluster partners (Carl Data Solutions, Teck Resources Ltd., Microsoft, Astra Smart Systems, i4C Innovation, the University of Victoria and Genome BC), MakeWay, RBC Tech for Nature, Regional District of Central Kootenay, Sitka Foundation, and the Vancouver Foundation.
DOI: 10.6084/m9.figshare.24025734
title: Testing the roles of time, diversification rates and niche conservatism in shaping the inverse latitudinal diversity gradient of Potentilla (Rosaceae).

description: Supplementary Materials for: Testing the roles of time, diversification rates and niche conservatism in shaping the inverse latitudinal diversity gradient of <i>Potentilla</i> (Rosaceae)
DOI: 10.6084/m9.figshare.24025734.v2
title: Testing the roles of time, diversification rates and niche conservatism in shaping the inverse latitudinal diversity gradient of Potentilla (Rosaceae).

description: Supplementary Materials for: Testing the roles of time, diversification rates and niche conservatism in shaping the inverse latitudinal diversity gradient of <i>Potentilla</i> (Rosaceae)
DOI: 10.5281/zenodo.8025276
title: Replication package for: Informality, Consumption Taxes and Redistribution

description: Replication package for: Informality, Consumption Taxes and Redistribution This permits the replication of the paper based on metadata from 32 micro household expenditure surveys.
DOI: 10.5281/zenodo.8025277
title: Replication package for: Informality, Consumption Taxes and Redistribution

description: Replication package for: Informality, Consumption Taxes and Redistribution This permits the replication of the paper based on metadata from 32 micro household expenditure surveys.
DOI: 10.5281/zenodo.8284123
title: Replication package for: Informality, Consumption Taxes and Redistribution

description: Replication package for: Informality, Consumption Taxes and Redistribution This permits the replication of the paper based on metadata from 32 micro household expenditure surveys.
DOI: 10.48511/1vce-h052
title: Willie Phillips Creek Hydrometric

description: This dataset contains hydrometric and water temperature data for Willie Phillips Creek hydrometric station. This site is part of the Living Lakes Canada Columbia Basin Water Monitoring Framework program. Willie Phillips Creek was selected for monitoring Yaq̓it ʔa·knuqⱡi‘it priorities. The data is being collected to track the impacts of climate change on Columbia Basin water supply and support community climate adaptation. Monitoring has been implemented on this site. Data will be added soon.

Province of BC, Healthy Watersheds Initiative partners (Stronger BC, Real Estate Foundation of BC, Watersheds BC), Province of BC, Columbia Basin Trust, Canada’s Digital Technology Supercluster partners (Carl Data Solutions, Teck Resources Ltd., Microsoft, Astra Smart Systems, i4C Innovation, the University of Victoria and Genome BC), MakeWay, RBC Tech for Nature, Regional District of Central Kootenay, Sitka Foundation, and the Vancouver Foundation.
DOI: 10.14469/hpc/12996
title: Endo_TS1_G16_PCM_chloroform_def2tzvpp_v_01

description: Kinisot.py command line KIE calculation: "python3 /usr/local/bin/Kinisot.py REACTANT.log TS.log --iso ATOM -t TEMP", where ATOM is number label of transferred proton and TEMP is the temperature (Kelvin)
DOI: 10.14469/hpc/12997
title: Endo_TS1_G16_PCM_chlorobenzene_def2tzvpp_v_01_reactant

description: Gaussian 16 (C01) calculation
DOI: 10.14469/hpc/12999
title: Endo_TS1_G16_PCM_carbon_tetrachloride_def2tzvpp_v_01_reactant

description: Gaussian 16 (C01) calculation
DOI: 10.14469/hpc/13000
title: Endo_TS1_G16_PCM_carbon_tetrachloride_def2tzvpp_v_01

description: Kinisot.py command line KIE calculation: "python3 /usr/local/bin/Kinisot.py REACTANT.log TS.log --iso ATOM -t TEMP", where ATOM is number label of transferred proton and TEMP is the temperature (Kelvin)
DOI: 10.14469/hpc/13001
title: Endo_TS1_G16_PCM_DCM_def2tzvpp_v_01_reactant

description: Gaussian 16 (C01) calculation
DOI: 10.14469/hpc/13002
title: Endo_TS1_G16_PCM_DCM_def2tzvpp_v_01

description: Kinisot.py command line KIE calculation: "python3 /usr/local/bin/Kinisot.py REACTANT.log TS.log --iso ATOM -t TEMP", where ATOM is number label of transferred proton and TEMP is the temperature (Kelvin)
DOI: 10.14469/hpc/12991
title: Endo_TS1_G16_PCM_chlorobenzene_def2tzvpp_v_01_reactant

description: Gaussian 16 (C01) calculation
DOI: 10.14469/hpc/12992
title: Endo_TS1_G16_PCM_chlorobenzene_def2tzvpp_v_01

description: Kinisot.py command line KIE calculation: "python3 /usr/local/bin/Kinisot.py REACTANT.log TS.log --iso ATOM -t TEMP", where ATOM is number label of transferred proton and TEMP is the temperature (Kelvin)
DOI: 10.14469/hpc/12993
title: Endo_TS1_G16_PCM_dichloroethane_def2tzvpp_v_01_reactant

description: Gaussian 16 (C01) calculation
DOI: 10.14469/hpc/12994
title: Endo_TS1_G16_PCM_dichloroethane_def2tzvpp_v_01

description: Kinisot.py command line KIE calculation: "python3 /usr/local/bin/Kinisot.py REACTANT.log TS.log --iso ATOM -t TEMP", where ATOM is number label of transferred proton and TEMP is the temperature (Kelvin)
DOI: 10.14469/hpc/12995
title: Endo_TS1_G16_PCM_chloroform_def2tzvpp_v_01_reactant

description: Gaussian 16 (C01) calculation
DOI: 10.14469/hpc/13077
title: Endo_TS1_G16_PCM_chloroform_def2tzvpp_v_01_reactant_bis(dimethylamine)

description: Gaussian 16 (C01) calculation
DOI: 10.14469/hpc/13078
title: Endo_TS1_G16_PCM_chloroform_def2tzvpp_v_02_bis(trifluoromethyl)

description: Kinisot.py command line KIE calculation: "python3 /usr/local/bin/Kinisot.py REACTANT.log TS.log --iso ATOM -t TEMP", where ATOM is number label of transferred proton and TEMP is the temperature (Kelvin)
DOI: 10.14469/hpc/13079
title: Endo_TS1_G16_PCM_chloroform_def2tzvpp_v_01_reactant_bis(trifluoromethyl)

description: Gaussian 16 (C01) calculation
DOI: 10.14469/hpc/13091
title: Endo_TS1_G16_PCM_DCM_def2tzvpp_v_01_reactant_bis(dimethylamine)

description: Gaussian 16 (C01) calculation
DOI: 10.14469/hpc/13092
title: Endo_TS1_G16_PCM_DCM_def2tzvpp_v_02_bis(trifluoromethyl)

description: Kinisot.py command line KIE calculation: "python3 /usr/local/bin/Kinisot.py REACTANT.log TS.log --iso ATOM -t TEMP", where ATOM is number label of transferred proton and TEMP is the temperature (Kelvin)
DOI: 10.14469/hpc/13094
title: Endo_TS1_G16_PCM_DCM_def2tzvpp_v_01_reactant_bis(trifluoromethyl)

description: Gaussian 16 (C01) calculation
DOI: 10.14469/hpc/13122
title: Endo_TS1_G16_PCM_chloroform_def2tzvpp_v_01_reactant_bis(dimethylamine)_stretched

description: Kinisot.py command line KIE calculation: "python3 /usr/local/bin/Kinisot.py REACTANT.log TS.log --iso ATOM -t TEMP", where ATOM is number label of transferred proton and TEMP is the temperature (Kelvin)
DOI: 10.14469/hpc/13073
title: Endo_TS1_G16_PCM_chloroform_def2tzvpp_v_02_2_explicit_solvents

description: Kinisot.py command line KIE calculation: "python3 /usr/local/bin/Kinisot.py REACTANT.log TS.log --iso ATOM -t TEMP", where ATOM is number label of transferred proton and TEMP is the temperature (Kelvin)
DOI: 10.14469/hpc/13076
title: Endo_TS1_G16_PCM_chloroform_def2tzvpp_v_02_bis(dimethylamine)

description: Kinisot.py command line KIE calculation: "python3 /usr/local/bin/Kinisot.py REACTANT.log TS.log --iso ATOM -t TEMP", where ATOM is number label of transferred proton and TEMP is the temperature (Kelvin)
DOI: 10.14469/hpc/13110
title: Endo_TS1_G16_PCM_DCM_def2tzvpp_v_02_bis(dimethylamine)

description: Kinisot.py command line KIE calculation: "python3 /usr/local/bin/Kinisot.py REACTANT.log TS.log --iso ATOM -t TEMP", where ATOM is number label of transferred proton and TEMP is the temperature (Kelvin)
DOI: 10.14469/hpc/13124
title: Endo_TS1_G16_PCM_DCM_def2tzvpp_v_01_reactant_bis(dimethylamine)_stretched

description: Kinisot.py command line KIE calculation: "python3 /usr/local/bin/Kinisot.py REACTANT.log TS.log --iso ATOM -t TEMP", where ATOM is number label of transferred proton and TEMP is the temperature (Kelvin)
DOI: 10.14469/hpc/13072
title: Endo_TS1_G16_PCM_chloroform_def2tzvpp_v_02_reactant_2_explicit_solvents

description: Gaussian 16 (C01) calculation
DOI: 10.14469/hpc/13074
title: Endo_TS1_G16_PCM_chloroform_def2tzvpp_v_02_reactant_1_explicit_solvent

description: Gaussian 16 (C01) calculation
DOI: 10.14469/hpc/13075
title: Endo_TS1_G16_PCM_chloroform_def2tzvpp_v_02_1_explicit_solvent

description: Kinisot.py command line KIE calculation: "python3 /usr/local/bin/Kinisot.py REACTANT.log TS.log --iso ATOM -t TEMP", where ATOM is number label of transferred proton and TEMP is the temperature (Kelvin)
DOI: 10.34740/kaggle/dsv/6364517
title: 📒Meta Kaggle ported to MS SQL SERVER 2022 DB
DOI: 10.6084/m9.figshare.23988312
title: MEANGS responses to letter to editor

description: MEANGS data for responses the letter to editor.
DOI: 10.6084/m9.figshare.23988312.v1
title: MEANGS responses to letter to editor

description: MEANGS data for responses the letter to editor.
DOI: 10.25345/c58w38c67
title: MassIVE MSV000092752 - LabeledGlucoseCarnitineEndpointJune2023
title: Endpoint data for Chagas experiment with use of L-carnitine for treatment. Used various different organs.
DOI: 10.48511/7t0w-hj46
title: Edwards Lake Level

description: This dataset contains lake level data for Edwards Lake level logger. This site is part of the Living Lakes Canada Columbia Basin Water Monitoring Framework program. Edwards Lake was selected for monitoring because it was identified as a priority by the Yaq̓it ʔa·knuqⱡi ‘it. The data is being collected to track the impacts of climate change on Columbia Basin water supply and support community climate adaptation. Monitoring has been implemented on this site. Data will be added soon.

Province of BC, Healthy Watersheds Initiative partners (Stronger BC, Real Estate Foundation of BC, Watersheds BC), Province of BC, Columbia Basin Trust, Canada’s Digital Technology Supercluster partners (Carl Data Solutions, Teck Resources Ltd., Microsoft, Astra Smart Systems, i4C Innovation, the University of Victoria and Genome BC), MakeWay, RBC Tech for Nature, Regional District of Central Kootenay, Sitka Foundation, and the Vancouver Foundation.
DOI: 10.48511/eq4z-cc79
title: Kindersley Creek Hydrometric

description: This dataset contains hydrometric and water temperature data for Kindersley Creek hydrometric station. This site is part of the Living Lakes Canada Columbia Basin Water Monitoring Framework program. Kindersley Creek was selected for monitoring for its geographic distribution and its opposite aspect to Dunbar Creek. The data is being collected to track the impacts of climate change on Columbia Basin water supply and support community climate adaptation. Monitoring has been implemented on this site. Data will be added soon.

Province of BC, Healthy Watersheds Initiative partners (Stronger BC, Real Estate Foundation of BC, Watersheds BC), Province of BC, Columbia Basin Trust, Canada’s Digital Technology Supercluster partners (Carl Data Solutions, Teck Resources Ltd., Microsoft, Astra Smart Systems, i4C Innovation, the University of Victoria and Genome BC), MakeWay, RBC Tech for Nature, Regional District of Central Kootenay, Sitka Foundation, and the Vancouver Foundation.
DOI: 10.25345/c55717z66
title: MassIVE MSV000092753 - Labeled Glucose Timepoint Pilot
title: Pilot for testing various timepoints of labeling in mice using C13 labeled glucose
DOI: 10.48511/1vvd-1911
title: Jones Creek Hydrometric

description: This dataset contains hydrometric and water temperature data for Jones Creek hydrometric station. This site is part of the Living Lakes Canada Columbia Basin Water Monitoring Framework program. Jones Creek was selected for monitoring drawdown from farming, increased human habitation, new structures to facilitate forest harvesting, loss of forest cover and changes to snowpack. The data is being collected to track the impacts of climate change on Columbia Basin water supply and support community climate adaptation. Monitoring has been implemented on this site. Data will be added soon.

Province of BC, Healthy Watersheds Initiative partners (Stronger BC, Real Estate Foundation of BC, Watersheds BC), Province of BC, Columbia Basin Trust, Canada’s Digital Technology Supercluster partners (Carl Data Solutions, Teck Resources Ltd., Microsoft, Astra Smart Systems, i4C Innovation, the University of Victoria and Genome BC), MakeWay, RBC Tech for Nature, Regional District of Central Kootenay, Sitka Foundation, and the Vancouver Foundation.
DOI: 10.5281/zenodo.8284188
title: forpus_spengeli_zanfona_1.fasta.gz

description: .
DOI: 10.5281/zenodo.8284187
title: forpus_spengeli_zanfona_1.fasta.gz

description: .
DOI: 10.48511/1f1v-m675
title: Fish Lake Level

description: This dataset contains lake level data for Fish Lake level logger. This site is part of the Living Lakes Canada Columbia Basin Water Monitoring Framework program. Fish Lake was selected for monitoring as it flows into Dunbar Creek and represents a mid-elevation lake. The data is being collected to track the impacts of climate change on Columbia Basin water supply and support community climate adaptation. Monitoring has been implemented on this site. Data will be added soon.

Province of BC, Healthy Watersheds Initiative partners (Stronger BC, Real Estate Foundation of BC, Watersheds BC), Province of BC, Columbia Basin Trust, Canada’s Digital Technology Supercluster partners (Carl Data Solutions, Teck Resources Ltd., Microsoft, Astra Smart Systems, i4C Innovation, the University of Victoria and Genome BC), MakeWay, RBC Tech for Nature, Regional District of Central Kootenay, Sitka Foundation, and the Vancouver Foundation.
DOI: 10.5281/zenodo.6288138
title: AlphScore_final dataset

description: This file contains AlphScore_final as described in our associated publication. The file is based on dbNSFP 4.2a, contains a header and is tab-separated and compressed using bgzip. The columns contain the following content: #chr chromosome (hg38) pos(1-based) position (hg38) ref reference allele alt alternative allele aaref reference amino acid aaalt alternative amino acid rs_dbSNP rs number hg19_chr chromosome (hg19) hg19_pos(1-based) position (hg19) ID variant id in the format: chromosome:position:reference amino acid:alternative amino acid genename genename, taken from dbNSFP Uniprot_acc_split The Uniprot-IDs of the structural models that were used to create AlphScore_final (multiple entries separated by ; ) Uniprot_acc Uniprot_acc as provided by dbNSFP HGVSp_VEP_split The missense variant(s) as used to create AlphScore_final; these variant(s) correspond(s) to the Uniprot_acc_split HGVSp_VEP HGVSp_VEP as provided by dbNSFP CADD_raw CADD_raw as provided by dbNSFP REVEL_score REVEL_score as provided by dbNSFP DEOGEN2_score DEOGEN2_score as provided by dbNSFP b_factor AlphaFold's pLDDT-score of the residue (if a variant affects multiple proteins, the values of the proteins as indicated in Uniprot_acc_split are given separated by ; ). SOLVENT_ACCESSIBILITY_core Solvent accessibility of the residue as calculated for C-alpha by DSSP (if a variant affects multiple proteins, the values of the proteins as indicated in Uniprot_acc_split are given separated by ; ). in_gnomad_train TRUE if the variant was in the gnomAD set used for training in_clinvar_ds TRUE if the variant was in the ClinVar set used for validation / training of combined scores AlphScore This column corresponds to AlphScore_final glm_AlphCadd This column corresponds to AlphScore_final + CADD glm_AlphRevel This column corresponds to AlphScore_final + REVEL glm_RevelCadd This column corresponds to REVEL + CADD glm_AlphRevelCadd This column corresponds to AlphScore_final + REVEL + CADD glm_AlphDeogen This column corresponds to AlphScore_final + DEOGEN2 glm_CaddDeogen This column corresponds to CADD + DEOGEN2 glm_DeogenRevel This column corresponds to DEOGEN2 + REVEL glm_AlphDeogenRevel This column corresponds to AlphScore_final + DEOGEN2 + REVEL glm_AlphCaddDeogen This column corresponds to AlphScore_final + CADD + DEOGEN2 glm_CaddDeogenRevel This column corresponds to CADD + DEOGEN2 + REVEL Note that the Creative Commons license applies only to the values of AlphScore_final. REVEL and CADD scores as well as combined scores containing REVEL and CADD are not licensed for commercial use. The full list of references can be found in our manuscript.
description: These are updated files which include chromosome 22. In version 1 of the files, chromosome 22 did not exist. The ranges and interpretations of the scores are the same as in the first version of the files.