cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7103561.v1
title: MOESM2 of A digital elevation model for simulating the 1945 Makran tsunami in Karachi Harbour

description: Additional file 2: Table S1. Soundings digitized from the 1955 edition of Admiralty nautical chart (BA40), “Karáchi Harbour”. Table S2. Soundings digitized from the 1939 edition of Admiralty nautical chart (BA40), “Karáchi Harbour”.
DOI: 10.6084/m9.figshare.7103528
title: MOESM1 of The effect of virtual reality-based balance training on motor learning and postural control in healthy adults: a randomized preliminary study

description: Additional file 1. The gradient of slope determined from all sessions in each game. This excel file describes the way to compute the gradient of slope to define the plateau phase in each game. The scores from a fitted curve, using the power law function, are used to determine the slope.
DOI: 10.6084/m9.figshare.7103528.v1
title: MOESM1 of The effect of virtual reality-based balance training on motor learning and postural control in healthy adults: a randomized preliminary study

description: Additional file 1. The gradient of slope determined from all sessions in each game. This excel file describes the way to compute the gradient of slope to define the plateau phase in each game. The scores from a fitted curve, using the power law function, are used to determine the slope.
DOI: 10.6084/m9.figshare.7103510
title: Additional file 2: of Paleoceanographic history of the Japan Sea over the last 9.5 million years inferred from radiolarian assemblages (IODP Expedition 346 Sites U1425 and U1430)

description: Raw data (%) of the species used in this study (U1430). (XLSX 42 kb)
DOI: 10.6084/m9.figshare.7103510.v1
title: Additional file 2: of Paleoceanographic history of the Japan Sea over the last 9.5 million years inferred from radiolarian assemblages (IODP Expedition 346 Sites U1425 and U1430)

description: Raw data (%) of the species used in this study (U1430). (XLSX 42 kb)
DOI: 10.6084/m9.figshare.7103489
title: Additional file 1: of Paleoceanographic history of the Japan Sea over the last 9.5 million years inferred from radiolarian assemblages (IODP Expedition 346 Sites U1425 and U1430)

description: Raw data (%) of the species used in this study (U1425). (XLSX 84 kb)
DOI: 10.6084/m9.figshare.7103489.v1
title: Additional file 1: of Paleoceanographic history of the Japan Sea over the last 9.5 million years inferred from radiolarian assemblages (IODP Expedition 346 Sites U1425 and U1430)

description: Raw data (%) of the species used in this study (U1425). (XLSX 84 kb)
DOI: 10.6084/m9.figshare.7103369
title: Additional file 2: of Predicting recurrence of Clostridium difficile infection following encapsulated fecal microbiota transplantation

description: Batch file for sequencing processing. (TXT 12 kb)
DOI: 10.6084/m9.figshare.7103369.v1
title: Additional file 2: of Predicting recurrence of Clostridium difficile infection following encapsulated fecal microbiota transplantation

description: Batch file for sequencing processing. (TXT 12 kb)
DOI: 10.6084/m9.figshare.7103288
title: Additional file 1: of Burden of albinism: development and validation of a burden assessment tool

description: French and English (US) versions of the BoA questionnaire. (XLSX 10 kb)
DOI: 10.6084/m9.figshare.7103285
title: MOESM1 of Exploring non-linear distance metrics in the structureâ activity space: QSAR models for human estrogen receptor

description: Additional file 1. Supporting information.
DOI: 10.6084/m9.figshare.7103285.v1
title: MOESM1 of Exploring non-linear distance metrics in the structureâ activity space: QSAR models for human estrogen receptor

description: Additional file 1. Supporting information.
DOI: 10.6084/m9.figshare.7103288.v1
title: Additional file 1: of Burden of albinism: development and validation of a burden assessment tool

description: French and English (US) versions of the BoA questionnaire. (XLSX 10 kb)
DOI: 10.6084/m9.figshare.7103243
title: MOESM1 of Effects of mutations in the effector domain of influenza A virus NS1 protein

description: Additional file 1: Table S1. Mascot search results from LC-MS analysis of the novel polypeptide band in lane 8 of Fig.Â 2c. The data include a summary of protein IDs followed by details on the individual peptide hits.
DOI: 10.6084/m9.figshare.7103108
title: Phenotypic similarity between fruits of Gevuina avellana (Proteaceae) and wasp-induced galls of Nothofagus dombeyi (Nothofagaceae) does not protect fruits from predation by rodents

description: ABSTRACT Fruits of Gevuina avellana (Proteaceae) seem to mimic wasp-induced galls of Nothofagus dombeyi (Nothofagaceae) to escape predation by rodents, which may change both spatially and temporarily. The objective of this study was to evaluate the similarity between the fruits of G. avellana and the galls of N. dombeyi and to determine if this similarity protects fruits from predation by rodents in a disturbed temperate forest. We evaluated: i) the similarity between fruits and galls by measuring length, diameter, weight and color; and ii) the effects of galls on fruit predation by offering them to rodents in varying proportions, in a forest and a meadow, over two years. Fruits and galls showed similar phenotypes but fruits were more consumed than galls, even at low fruit frequencies, suggesting that their similarities are not due to mimicry. Fruits escaped predation more in the meadow than in the forest, particularly during the second year, thus indicating spatio-temporal variability in the phenomenon. The similarity between fruits and galls seems to be the result of phylogenetic and/or developmental constraints, rather than the result of a Darwinian coevolutionary pathway mediated by rodents. However, mimicry may happen with other dry-fruited plants inhabiting deforested habitats, which encourages further studies.
DOI: 10.6084/m9.figshare.7103243.v1
title: MOESM1 of Effects of mutations in the effector domain of influenza A virus NS1 protein

description: Additional file 1: Table S1. Mascot search results from LC-MS analysis of the novel polypeptide band in lane 8 of Fig.Â 2c. The data include a summary of protein IDs followed by details on the individual peptide hits.
DOI: 10.6084/m9.figshare.7103108.v1
title: Phenotypic similarity between fruits of Gevuina avellana (Proteaceae) and wasp-induced galls of Nothofagus dombeyi (Nothofagaceae) does not protect fruits from predation by rodents

description: ABSTRACT Fruits of Gevuina avellana (Proteaceae) seem to mimic wasp-induced galls of Nothofagus dombeyi (Nothofagaceae) to escape predation by rodents, which may change both spatially and temporarily. The objective of this study was to evaluate the similarity between the fruits of G. avellana and the galls of N. dombeyi and to determine if this similarity protects fruits from predation by rodents in a disturbed temperate forest. We evaluated: i) the similarity between fruits and galls by measuring length, diameter, weight and color; and ii) the effects of galls on fruit predation by offering them to rodents in varying proportions, in a forest and a meadow, over two years. Fruits and galls showed similar phenotypes but fruits were more consumed than galls, even at low fruit frequencies, suggesting that their similarities are not due to mimicry. Fruits escaped predation more in the meadow than in the forest, particularly during the second year, thus indicating spatio-temporal variability in the phenomenon. The similarity between fruits and galls seems to be the result of phylogenetic and/or developmental constraints, rather than the result of a Darwinian coevolutionary pathway mediated by rodents. However, mimicry may happen with other dry-fruited plants inhabiting deforested habitats, which encourages further studies.
DOI: 10.6084/m9.figshare.7103102
title: ASSESSMENT OF UNIVERSITY ENTRY WRITING EXAMS: FROM THEORY TO PRACTICE

description: ABSTRACT This paper presents a reflection about the assessment of large scale writing tests. Although this research, in a broader perspective, is situated in the interface between text and discourse theories and educational assessment studies, this work is mainly focused on the textual and discursive analysis undertaken during the assessment of university entry writing exams. The concept of "gap" is analyzed, which operationalises the evaluation of the argumentative quality of essays in the scoring guide used by the Fundação para o Vestibular da Unesp (Vunesp). The concept of discursive ethos (Maingueneau, 2005, 2010) is the main theoretical notion mobilized for the analyses. The corpus comprises a set of essays produced by occasion of a highly competitive university entry exam. The objective is to demonstrate how the concept of gap works and how it is an example of evaluation parameter that responds to both criteria of applicability and theoretical robustness, a central demand for the elaboration of scoring tools for assessment of large scale writing tests.
DOI: 10.6084/m9.figshare.7103105
title: Detection of herpes simplex-1 and -2 and varicella zoster virus by quantitative real-time polymerase chain reaction in corneas from patients with bacterial keratitis

description: ABSTRACT Objective: Bacterial keratitis occurs worldwide, and despite recent developments, it remains a potentially blinding condition. This study assesses the presence of herpes simplex virus (HSV-1 and -2) and varicella zoster virus (VZV) by quantitative real-time polymerase chain reaction (qPCR) in corneal scrapings from patients with bacterial keratitis. Methods: A total of 65 patients with clinical diagnoses of infectious corneal ulcers prospectively underwent clinical eye examinations. Corneal scrapings were investigated by Gram staining, Giemsa staining, culture, and qPCR (the study group). Risk factors and epidemiological data were recorded. The control group comprising 25 eyes with typical herpes dendritic keratitis was also analyzed by qPCR. Results: From the study group (n=65), nine patients (13.8%) had negative smears, cultures, and qPCR findings. Fifty-six (86.2%) patients had positive cultures: 51 for bacteria, 4 for fungi, and 1 for amoebae. Of the patients who had positive bacterial cultures, qPCR identified 10 patients who were also positive for virus: one for VZV and nine for HSV-1. Of the 25 patients in the control group, 21 tested positive for HSV-1 by qPCR analysis. Conclusions: Herpes may be present in patients with bacterial corneal ulcers, and qPCR may be useful in its detection.
DOI: 10.6084/m9.figshare.7103105.v1
title: Detection of herpes simplex-1 and -2 and varicella zoster virus by quantitative real-time polymerase chain reaction in corneas from patients with bacterial keratitis

description: ABSTRACT Objective: Bacterial keratitis occurs worldwide, and despite recent developments, it remains a potentially blinding condition. This study assesses the presence of herpes simplex virus (HSV-1 and -2) and varicella zoster virus (VZV) by quantitative real-time polymerase chain reaction (qPCR) in corneal scrapings from patients with bacterial keratitis. Methods: A total of 65 patients with clinical diagnoses of infectious corneal ulcers prospectively underwent clinical eye examinations. Corneal scrapings were investigated by Gram staining, Giemsa staining, culture, and qPCR (the study group). Risk factors and epidemiological data were recorded. The control group comprising 25 eyes with typical herpes dendritic keratitis was also analyzed by qPCR. Results: From the study group (n=65), nine patients (13.8%) had negative smears, cultures, and qPCR findings. Fifty-six (86.2%) patients had positive cultures: 51 for bacteria, 4 for fungi, and 1 for amoebae. Of the patients who had positive bacterial cultures, qPCR identified 10 patients who were also positive for virus: one for VZV and nine for HSV-1. Of the 25 patients in the control group, 21 tested positive for HSV-1 by qPCR analysis. Conclusions: Herpes may be present in patients with bacterial corneal ulcers, and qPCR may be useful in its detection.
DOI: 10.6084/m9.figshare.7103099
title: EVALUATION OF USABILITY OF MAPS OF DIFFERENT SCALES PRESENTED IN AN IN-CAR ROUTE GUIDANCE AND NAVIGATION SYSTEM

description: Abstract Noise from the information communication process produced by the interfaces of navigation systems has overloaded drivers' cognitive processing systems and increased the probability of traffic accidents. This work evaluates the usability of maps of different scales in a prototype route guidance and navigation system. The maps were designed on basic cartographic communication principles, such as perceptive grouping and figure-ground segregation, as well drivers’ requirements for performing a tactical task. Two different scales were adopted, 1:3,000 and 1:6,000, and the maps implemented in the prototype. A total of 52 subjects (26 males and 26 females) participated in an experiment performed in a driving simulator. The maps describe an urban route composed of 13 simple and complex maneuvers. The drivers’ mental workload was measured in terms of visual demand, navigational error and subjective preference. Results reveal that the usability of maps is influenced by map scale variation, and this is related to maneuver complexity. Also, an association between drivers’ visual demand and gender was found, and this was related to drivers’ spatial ability. More implications are presented and discussed.
DOI: 10.6084/m9.figshare.7103102.v1
title: ASSESSMENT OF UNIVERSITY ENTRY WRITING EXAMS: FROM THEORY TO PRACTICE

description: ABSTRACT This paper presents a reflection about the assessment of large scale writing tests. Although this research, in a broader perspective, is situated in the interface between text and discourse theories and educational assessment studies, this work is mainly focused on the textual and discursive analysis undertaken during the assessment of university entry writing exams. The concept of "gap" is analyzed, which operationalises the evaluation of the argumentative quality of essays in the scoring guide used by the Fundação para o Vestibular da Unesp (Vunesp). The concept of discursive ethos (Maingueneau, 2005, 2010) is the main theoretical notion mobilized for the analyses. The corpus comprises a set of essays produced by occasion of a highly competitive university entry exam. The objective is to demonstrate how the concept of gap works and how it is an example of evaluation parameter that responds to both criteria of applicability and theoretical robustness, a central demand for the elaboration of scoring tools for assessment of large scale writing tests.
DOI: 10.6084/m9.figshare.7103096
title: Keratoconus progression is not inhibited by reducing eyelid muscular force with botulinum toxin A treatment: a randomized trial

description: ABSTRACT Purpose: To evaluate whether reducing eyelid muscular force through the administration of botulinum toxin type A (BTX-A) to the orbicularis oculi muscles of patients with keratoconus affected corneal parameters indicative of disease progression. Methods: In this prospective parallel randomized clinical trial, 40 eyes of 40 patients with keratoconus were randomized into equally sized control and BTX-A groups. Patients in the BTX-A group received subcutaneous BTX-A injections into the orbicularis muscle. The control group received no intervention. Palpebral fissure height, best spectacle-corrected visual acuity (BSCVA), and corneal topographic parameters were evaluated at baseline and at 3-, 6-, 12-, and 18-month follow-ups. Results: The mean ± standard deviation vertical palpebral fissure heights were 9.74 ± 1.87 mm and 9.45 ± 1.47 mm at baseline in the control and BTX-A groups, respectively, and 10.0 ± 1.49 mm and 9.62 ± 1.73 mm at 18 months, with no significant difference between the groups (p=0.337). BSCVA values were 0.63 ± 0.56 and 0.60 ± 0.27 at baseline in the control and BTX-A groups (p=0.643), and 0.52 ± 0.59 and 0.45 ± 0.26 at 18 months, again with no significant difference between the groups (p=0.452). In addition, there were no statistical differences between the groups at 18 months for the three keratometry topographic parameters: flattest (K1), steepest (K2), and mean (Km) keratometry (p=0.562). Conclusion: BTX-A inhibition of eyelid force generation did not result in detectable changes in corneal parameters in keratoconic patients during 18 months of follow-up.
DOI: 10.6084/m9.figshare.7103099.v1
title: EVALUATION OF USABILITY OF MAPS OF DIFFERENT SCALES PRESENTED IN AN IN-CAR ROUTE GUIDANCE AND NAVIGATION SYSTEM

description: Abstract Noise from the information communication process produced by the interfaces of navigation systems has overloaded drivers' cognitive processing systems and increased the probability of traffic accidents. This work evaluates the usability of maps of different scales in a prototype route guidance and navigation system. The maps were designed on basic cartographic communication principles, such as perceptive grouping and figure-ground segregation, as well drivers’ requirements for performing a tactical task. Two different scales were adopted, 1:3,000 and 1:6,000, and the maps implemented in the prototype. A total of 52 subjects (26 males and 26 females) participated in an experiment performed in a driving simulator. The maps describe an urban route composed of 13 simple and complex maneuvers. The drivers’ mental workload was measured in terms of visual demand, navigational error and subjective preference. Results reveal that the usability of maps is influenced by map scale variation, and this is related to maneuver complexity. Also, an association between drivers’ visual demand and gender was found, and this was related to drivers’ spatial ability. More implications are presented and discussed.
DOI: 10.6084/m9.figshare.7103093
title: Yellow fever outbreak in Brazil: the puzzle of rapid viral spread and challenges for immunisation

description: We discuss the complex eco-social factors involved in the puzzle of the unexpected rapid viral spread in the ongoing Brazilian yellow fever (YF) outbreak, which has increased the reurbanisation risk of a disease without urban cases in Brazil since 1942. Indeed, this rapid spatial viral dissemination to the Southeast and South regions, now circulating in the Atlantic Forest fragments close to peri-urban areas of the main Brazilian megalopolises (São Paulo and Rio de Janeiro) has led to an exponential increase in the number of yellow fever cases. In less than 18 months, 1,833 confirmed cases and 578 deaths were recorded most of them reported in the Southeast region (99,9%). Large epizooties in monkeys and other non-human primates (NHPs) were communicated in the country with 732 YF virus (YFV) laboratory confirmed events only in the 2017/2018 monitoring period. We also discuss the peculiarities and similarities of the current outbreak when compared with previous great epidemics, examining several hypotheses to explain the recent unexpected acceleration of epizootic waves in the sylvatic cycle of the YFV together with the role of human, NHPs and mosquito mobility with respect to viral spread. We conclude that the most feasible hypothesis to explain this rapidity would be related to human behavior combined with ecological changes that promoted a significant increase in mosquito and NHP densities and their contacts with humans. We emphasize the urgent need for an adequate response to this outbreak such as extending immunisation coverage to the whole Brazilian population and developing novel strategies for immunisation of NHPs confined in selected reserve areas and zoos. Finally, we stress the urgent need to improve the quality of response in order to prevent future outbreaks and a catastrophic reurbanisation of the disease in Brazil and other South American countries. Continuous monitoring of YFV receptivity and vulnerability conditions with effective control of the urban vector Aedes aegypti and significant investments in YF vaccine production capacity and research and development for reduction of adverse effects are of the highest priority.
DOI: 10.6084/m9.figshare.7103096.v1
title: Keratoconus progression is not inhibited by reducing eyelid muscular force with botulinum toxin A treatment: a randomized trial

description: ABSTRACT Purpose: To evaluate whether reducing eyelid muscular force through the administration of botulinum toxin type A (BTX-A) to the orbicularis oculi muscles of patients with keratoconus affected corneal parameters indicative of disease progression. Methods: In this prospective parallel randomized clinical trial, 40 eyes of 40 patients with keratoconus were randomized into equally sized control and BTX-A groups. Patients in the BTX-A group received subcutaneous BTX-A injections into the orbicularis muscle. The control group received no intervention. Palpebral fissure height, best spectacle-corrected visual acuity (BSCVA), and corneal topographic parameters were evaluated at baseline and at 3-, 6-, 12-, and 18-month follow-ups. Results: The mean ± standard deviation vertical palpebral fissure heights were 9.74 ± 1.87 mm and 9.45 ± 1.47 mm at baseline in the control and BTX-A groups, respectively, and 10.0 ± 1.49 mm and 9.62 ± 1.73 mm at 18 months, with no significant difference between the groups (p=0.337). BSCVA values were 0.63 ± 0.56 and 0.60 ± 0.27 at baseline in the control and BTX-A groups (p=0.643), and 0.52 ± 0.59 and 0.45 ± 0.26 at 18 months, again with no significant difference between the groups (p=0.452). In addition, there were no statistical differences between the groups at 18 months for the three keratometry topographic parameters: flattest (K1), steepest (K2), and mean (Km) keratometry (p=0.562). Conclusion: BTX-A inhibition of eyelid force generation did not result in detectable changes in corneal parameters in keratoconic patients during 18 months of follow-up.
DOI: 10.6084/m9.figshare.7103093.v1
title: Yellow fever outbreak in Brazil: the puzzle of rapid viral spread and challenges for immunisation

description: We discuss the complex eco-social factors involved in the puzzle of the unexpected rapid viral spread in the ongoing Brazilian yellow fever (YF) outbreak, which has increased the reurbanisation risk of a disease without urban cases in Brazil since 1942. Indeed, this rapid spatial viral dissemination to the Southeast and South regions, now circulating in the Atlantic Forest fragments close to peri-urban areas of the main Brazilian megalopolises (São Paulo and Rio de Janeiro) has led to an exponential increase in the number of yellow fever cases. In less than 18 months, 1,833 confirmed cases and 578 deaths were recorded most of them reported in the Southeast region (99,9%). Large epizooties in monkeys and other non-human primates (NHPs) were communicated in the country with 732 YF virus (YFV) laboratory confirmed events only in the 2017/2018 monitoring period. We also discuss the peculiarities and similarities of the current outbreak when compared with previous great epidemics, examining several hypotheses to explain the recent unexpected acceleration of epizootic waves in the sylvatic cycle of the YFV together with the role of human, NHPs and mosquito mobility with respect to viral spread. We conclude that the most feasible hypothesis to explain this rapidity would be related to human behavior combined with ecological changes that promoted a significant increase in mosquito and NHP densities and their contacts with humans. We emphasize the urgent need for an adequate response to this outbreak such as extending immunisation coverage to the whole Brazilian population and developing novel strategies for immunisation of NHPs confined in selected reserve areas and zoos. Finally, we stress the urgent need to improve the quality of response in order to prevent future outbreaks and a catastrophic reurbanisation of the disease in Brazil and other South American countries. Continuous monitoring of YFV receptivity and vulnerability conditions with effective control of the urban vector Aedes aegypti and significant investments in YF vaccine production capacity and research and development for reduction of adverse effects are of the highest priority.