cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5517/ccdc.csd.cc2bq65g
title: CCDC 2166285: Experimental Crystal Structure Determination

description: Related Article: Joanna Krajewska, Krzysztof Nowicki, Krzysztof Durka, Paulina H. Marek-Urban, Patrycja Wińska, Tomasz Stępniewski, Krzysztof Woźniak, Agnieszka E. Laudy, Sergiusz Luliński|2022|RSC Advances|12|23099|doi:10.1039/D2RA03910A
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2bq66h
title: CCDC 2166286: Experimental Crystal Structure Determination

description: Related Article: Joanna Krajewska, Krzysztof Nowicki, Krzysztof Durka, Paulina H. Marek-Urban, Patrycja Wińska, Tomasz Stępniewski, Krzysztof Woźniak, Agnieszka E. Laudy, Sergiusz Luliński|2022|RSC Advances|12|23099|doi:10.1039/D2RA03910A
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2bq67j
title: CCDC 2166287: Experimental Crystal Structure Determination

description: Related Article: Joanna Krajewska, Krzysztof Nowicki, Krzysztof Durka, Paulina H. Marek-Urban, Patrycja Wińska, Tomasz Stępniewski, Krzysztof Woźniak, Agnieszka E. Laudy, Sergiusz Luliński|2022|RSC Advances|12|23099|doi:10.1039/D2RA03910A
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2bq68k
title: CCDC 2166288: Experimental Crystal Structure Determination

description: Related Article: Joanna Krajewska, Krzysztof Nowicki, Krzysztof Durka, Paulina H. Marek-Urban, Patrycja Wińska, Tomasz Stępniewski, Krzysztof Woźniak, Agnieszka E. Laudy, Sergiusz Luliński|2022|RSC Advances|12|23099|doi:10.1039/D2RA03910A
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2bq69l
title: CCDC 2166289: Experimental Crystal Structure Determination

description: Related Article: Joanna Krajewska, Krzysztof Nowicki, Krzysztof Durka, Paulina H. Marek-Urban, Patrycja Wińska, Tomasz Stępniewski, Krzysztof Woźniak, Agnieszka E. Laudy, Sergiusz Luliński|2022|RSC Advances|12|23099|doi:10.1039/D2RA03910A
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2bq6bm
title: CCDC 2166290: Experimental Crystal Structure Determination

description: Related Article: Joanna Krajewska, Krzysztof Nowicki, Krzysztof Durka, Paulina H. Marek-Urban, Patrycja Wińska, Tomasz Stępniewski, Krzysztof Woźniak, Agnieszka E. Laudy, Sergiusz Luliński|2022|RSC Advances|12|23099|doi:10.1039/D2RA03910A
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2bq6cn
title: CCDC 2166291: Experimental Crystal Structure Determination

description: Related Article: Joanna Krajewska, Krzysztof Nowicki, Krzysztof Durka, Paulina H. Marek-Urban, Patrycja Wińska, Tomasz Stępniewski, Krzysztof Woźniak, Agnieszka E. Laudy, Sergiusz Luliński|2022|RSC Advances|12|23099|doi:10.1039/D2RA03910A
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc24dxhz
title: CCDC 1978621: Experimental Crystal Structure Determination

description: Related Article: Yuki Imamura, Hikaru Mizutani, Masahisa Nakada|2022|Synlett|33|1556|doi:10.1055/a-1855-3777
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.34740/kaggle/dsv/4143427
title: YouTube Trending Video Dataset (updated daily)
DOI: 10.6084/m9.figshare.20748892
title: erythroxylum_pelleterianum_decontaminated_gx.fasta.gz

description: ......
DOI: 10.6084/m9.figshare.20748892.v1
title: erythroxylum_pelleterianum_decontaminated_gx.fasta.gz

description: ......
DOI: 10.6084/m9.figshare.20749510
title: Supplementary Material for: Upregulation of miRNA-26a enhances the apoptosis of cerebral neurons by targeting EphA2 and inhibiting the MAPK pathway

description: Neural tube defects (NTDs) constitute the second most common congenital malformation of the central nervous system. The pathogenesis of NTDs is not entirely clear. In recent years, microRNAs have become a hot spot in genetic and developmental biology research. The present study aimed to explore the potential role of microRNA (miRNA)-26a in NTDs and the underlying pathogenesis thereof. First, we found significantly increased miRNA-26a expression in fetuses with NTDs (p&lt;0.0001), which significantly downregulated EphA2 and ERK1 mRNA and protein expression levels in fetuses with NTDs compared to normal controls (p&lt;0.01). In addition, dual-luciferase reporter assay showed that miR-26a negatively regulated EphA2 by directly binding with the 3'-untranslated region of EphA2. Second, upregulation of miRNA-26a expression increased caspase 3 and 9 protein expression levels (p&lt;0.01); and decreased EphA2 mRNA and protein expression levels (p&lt;0.01), as well as ERK1 and SRF protein expression levels (p&lt;0.01) in mouse neural stem cells (NE-4C) and human astroblastoma cells (U87MG). Furthermore, the upregulation of miRNA-26a inhibited cell proliferation and enhanced apoptosis of NE-4C and U87MG cells (p&lt;0.05). Similar results were observed with the MAPK inhibitor PD98059 (p&lt;0.01). These results suggest that miR-26a downregulates EphA2 to regulate SRF through the MAPK pathway, which affects nervous system development miR-26a targets EphA2, modulates phosphorylation of MAPK/ERK(MEK) pathway, regulates SRF, and participates in regulating nervous cell proliferation and apoptosis. Dysregulation of the aforementioned mechanism may be involved in the pathogenesis of NTDs.
DOI: 10.6084/m9.figshare.20749510.v1
title: Supplementary Material for: Upregulation of miRNA-26a enhances the apoptosis of cerebral neurons by targeting EphA2 and inhibiting the MAPK pathway

description: Neural tube defects (NTDs) constitute the second most common congenital malformation of the central nervous system. The pathogenesis of NTDs is not entirely clear. In recent years, microRNAs have become a hot spot in genetic and developmental biology research. The present study aimed to explore the potential role of microRNA (miRNA)-26a in NTDs and the underlying pathogenesis thereof. First, we found significantly increased miRNA-26a expression in fetuses with NTDs (p&lt;0.0001), which significantly downregulated EphA2 and ERK1 mRNA and protein expression levels in fetuses with NTDs compared to normal controls (p&lt;0.01). In addition, dual-luciferase reporter assay showed that miR-26a negatively regulated EphA2 by directly binding with the 3'-untranslated region of EphA2. Second, upregulation of miRNA-26a expression increased caspase 3 and 9 protein expression levels (p&lt;0.01); and decreased EphA2 mRNA and protein expression levels (p&lt;0.01), as well as ERK1 and SRF protein expression levels (p&lt;0.01) in mouse neural stem cells (NE-4C) and human astroblastoma cells (U87MG). Furthermore, the upregulation of miRNA-26a inhibited cell proliferation and enhanced apoptosis of NE-4C and U87MG cells (p&lt;0.05). Similar results were observed with the MAPK inhibitor PD98059 (p&lt;0.01). These results suggest that miR-26a downregulates EphA2 to regulate SRF through the MAPK pathway, which affects nervous system development miR-26a targets EphA2, modulates phosphorylation of MAPK/ERK(MEK) pathway, regulates SRF, and participates in regulating nervous cell proliferation and apoptosis. Dysregulation of the aforementioned mechanism may be involved in the pathogenesis of NTDs.
DOI: 10.5281/zenodo.6653900
title: Video_frame_dataset

description: The dataset consists of video frames corresponding to different hand movements such as scroll-right, scroll-left, scroll-up, scroll-down, zoom-in, and zoom-out.
DOI: 10.5281/zenodo.6653899
title: Video_frame_dataset

description: The dataset consists of video frames corresponding to different hand movements such as scroll-right, scroll-left, scroll-up, scroll-down, zoom-in, and zoom-out.
DOI: 10.5281/zenodo.7037956
title: European power grid network with nodal prices

description: European power grid network with nodal prices as metadata
DOI: 10.5281/zenodo.7037955
title: European power grid network with nodal prices

description: European power grid network with nodal prices as metadata
DOI: 10.25574/53257
title: Chandra X-ray Observatory ObsId 53257
DOI: 10.25574/53263
title: Chandra X-ray Observatory ObsId 53263
DOI: 10.25574/53268
title: Chandra X-ray Observatory ObsId 53268
DOI: 10.25574/53273
title: Chandra X-ray Observatory ObsId 53273
DOI: 10.25574/53278
title: Chandra X-ray Observatory ObsId 53278
DOI: 10.25574/53283
title: Chandra X-ray Observatory ObsId 53283
DOI: 10.25574/53289
title: Chandra X-ray Observatory ObsId 53289
DOI: 10.25574/53300
title: Chandra X-ray Observatory ObsId 53300
DOI: 10.25574/53308
title: Chandra X-ray Observatory ObsId 53308
DOI: 10.25574/53313
title: Chandra X-ray Observatory ObsId 53313
DOI: 10.25574/53332
title: Chandra X-ray Observatory ObsId 53332
DOI: 10.25574/53339
title: Chandra X-ray Observatory ObsId 53339
DOI: 10.25574/53360
title: Chandra X-ray Observatory ObsId 53360
DOI: 10.25574/53362
title: Chandra X-ray Observatory ObsId 53362
DOI: 10.25574/53367
title: Chandra X-ray Observatory ObsId 53367
DOI: 10.25574/53375
title: Chandra X-ray Observatory ObsId 53375
DOI: 10.25574/53389
title: Chandra X-ray Observatory ObsId 53389
DOI: 10.25574/53399
title: Chandra X-ray Observatory ObsId 53399
DOI: 10.25574/53407
title: Chandra X-ray Observatory ObsId 53407
DOI: 10.25574/53416
title: Chandra X-ray Observatory ObsId 53416
DOI: 10.25574/53422
title: Chandra X-ray Observatory ObsId 53422
DOI: 10.5281/zenodo.7036360
title: Humid tropical vertebrates are at lower risk of extinction and population decline in forests with higher structural integrity

description: The four Excel workbooks contain processed data in the form of humid tropical forest area under each of multiple values of the Structural Condition Index (SCI), Forest Structural Integrity Index (FSII), and Human Footprint (HFP) for Mammal, Bird, Reptile and Amphibian species. The associated README text file contains metadata to describe the data in the xlsx workbooks. Python code to replicate geospatial analyses and R code to replicate statistical analyses are provided in the respective scripts. ArcGIS Pro is required to be installed prior to running the Python script.
DOI: 10.5281/zenodo.7036359
title: Humid tropical vertebrates are at lower risk of extinction and population decline in forests with higher structural integrity

description: The four Excel workbooks contain processed data in the form of humid tropical forest area under each of multiple values of the Structural Condition Index (SCI), Forest Structural Integrity Index (FSII), and Human Footprint (HFP) for Mammal, Bird, Reptile and Amphibian species. The associated README text file contains metadata to describe the data in the xlsx workbooks. Python code to replicate geospatial analyses and R code to replicate statistical analyses are provided in the respective scripts. ArcGIS Pro is required to be installed prior to running the Python script.
DOI: 10.25574/53428
title: Chandra X-ray Observatory ObsId 53428
DOI: 10.25574/53434
title: Chandra X-ray Observatory ObsId 53434
DOI: 10.25574/53442
title: Chandra X-ray Observatory ObsId 53442
DOI: 10.25574/53449
title: Chandra X-ray Observatory ObsId 53449
DOI: 10.25574/53455
title: Chandra X-ray Observatory ObsId 53455
DOI: 10.25574/53467
title: Chandra X-ray Observatory ObsId 53467
DOI: 10.25574/53481
title: Chandra X-ray Observatory ObsId 53481
DOI: 10.25574/53487
title: Chandra X-ray Observatory ObsId 53487
DOI: 10.5517/ccdc.csd.cc25j7b9
title: CCDC 2011600: Experimental Crystal Structure Determination

description: Related Article: Anatoly N. Vereshchagin, Taigib M. Iliyasov, Kirill A. Karpenko, Radmir N. Akchurin, Mikhail E. Minyaev|2022|Molecules|27|4367|doi:10.3390/molecules27144367
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc25j8tt
title: CCDC 2011646: Experimental Crystal Structure Determination

description: Related Article: Anatoly N. Vereshchagin, Taigib M. Iliyasov, Kirill A. Karpenko, Radmir N. Akchurin, Mikhail E. Minyaev|2022|Molecules|27|4367|doi:10.3390/molecules27144367
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc24fhqt
title: CCDC 1979186: Experimental Crystal Structure Determination

description: Related Article: Anatoly N. Vereshchagin, Taigib M. Iliyasov, Kirill A. Karpenko, Radmir N. Akchurin, Mikhail E. Minyaev|2022|Molecules|27|4367|doi:10.3390/molecules27144367
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.15128/r1s7526c436
title: Constraining the carbon budget of peat ecosystems : application of stoichiometry and enthalpy balances [dataset]

description: We consider how the stoichiometry and energy content of organic matter reservoirs and fluxes through and from a peatland enable the fluxes and storage of carbon within a peatland to be constrained. We include the elemental composition of the above- and below-ground biomass, litter, the peat profile, and the dissolved and particulate organic matter within a blanket bog in northern England for which the C budget has previously been measured. The study shows, based only on the elemental composition, and calculation of oxidation and energy contents, that: i) DOC in first-order streams is significantly more oxidised than in peat pore water but that there was no significant difference in organic carbon oxidation state down the peat profile; ii) The occurrence and speciation of N uptake and release in the peatland with N used and recycled can be predicted; iii) The relatively high oxidation state of DOC in stream water acts as an endpoint for peat-forming reactions; iv) Methanogenesis does not result in deep peat formation as it requirement for energy consumes too much organic matter to form residual peat at depth; v) Sulphate reduction does occur during the formation of deep peat; vi) Organic matter elemental composition could be constrained to within three bounding equations though the proportions of carbon species could not be specified. vii) The formation of deep peat in this catchment could only be achieved if the DOM in the peat pore water is the dominant electron acceptor and energy source in the production of residual organic matter; however, it is unclear as to the flux of DOM up or down the peat profile.
DOI: 10.5281/zenodo.7037995
title: Vaccination data for 4, level-3 health centres in central Uganda

description: This dataset describes the number of individuals who receiving vaccines at four level-3 health centers in four subcounties in central Uganda between 2017 and 2021.
DOI: 10.5281/zenodo.7037994
title: Vaccination data for 4, level-3 health centres in central Uganda

description: This dataset describes the number of individuals who receiving vaccines at four level-3 health centers in four subcounties in central Uganda between 2017 and 2021.
DOI: 10.48366/r214164
title: Existing smart building domain ontologies comparison

description: In the building domains, it is important to use existing energy sources as efficiently as possible, in other words, maximizing energy output and minimizing the energy cost. As energy efficiency is essential for social, economic, and environmental issues. Several energy-related ontologies are available for describing data of different types of building-related domains hence it is required to present all related ontologies in a commonplace. This comparison is presented to discuss energy-efficient ontologies for buildings and to explore their features, covered by existing ontologies.
DOI: 10.48366/r214162
title: SPARQL Query Optimization

description: Compares the performance of various algorithms evaluated using the LUBM benchmark.
DOI: 10.34740/kaggle/dsv/4143573
title: 2021 World Population (updated daily)
DOI: 10.15151/esrf-es-851626422
title: Cryo-EM structure of D-family DNA polymerase in a ternary elongation mode

description: PolD is an archaeal replicative DNA polymerase that possesses an atypical catalytic core (two-barrel) that is only found in RNA polymerases. We have reported he individual crystal structures of each subunit of PolD (Sauguet et al. 2016) as well as the Cryo-EM structure of PolD in complex with DNA (Raia et al , 2019) and PCNA (a processivity factor) (Madru et al. 2020). So far, the structure of the ternary complex of PolD with an incoming nucleotide and a DNA or RNA primer across a DNA template has not yet been resolved (Elongation mode). Such a structure has been challenging to obtain with a wild type version of PolD due to the flexibility of the primer substrate in the protein, we therefore created two different PolD variants (each including a different set of mutations) that showed to stabilize the elongation mode of PolD. Resolving these structures would be crucial to understand the positioning of the nucleotide in such a DNA polymerase with a unique catalytic core fold.
DOI: 10.15151/esrf-es-899047700
title: cryoEM structure of Malaria proteins

description: Malaria is a life-threatening disease that kills over 400,000 people each year and affects an estimated 229 million people worldwide. Sub-Saharan Africa bears the greatest health, social and economic impact of malaria, with approximately 370,000 deaths in 2020. It is estimated that approximately 3 billion USD is spent annually on malaria control. We aim to design novel inhibitors for the malaria parasite UAP enzyme that could potentially block the transmission of the parasite from mosquitoes to humans. We will begin by determining the structure of the malaria parasite UAP enzyme by X-ray crystallography or cryogenic electron microscopy
DOI: 10.15151/esrf-es-895035980
title: Study of molecular mechanisms of a Mycobacterium tuberculosis repressor by CryoEM analysis

description: During our screens for finding new small molecules with anti-TB capacity, we identified a gene controlling the expression of a putative efflux pump in Mycobacterium tuberculosis, the causative agent of TB. Gene names are voluntarily omitted, for confidentiality reason. The gene product is a repressor protein belonging to a well-known family of transcriptional factors whose mechanism of action has never been explicitly demonstrated. Furthermore, controlling the action of this repressor may have therapeutic potential when combined with the use of some commercial anti-TB drugs. Hence, to modulate activity of the repressor, we first must gain insight into how this protein works. This question will be addressed in the present project by using cryo-EM thorough analysis in combination with the functional data already acquired
DOI: 10.15151/esrf-es-883953464
title: The Iberian cryoEM community BAG

description: The Iberian cryoEM BAG is a large consortium (&gt; 30 groups) composed of Portuguese and Spanish groups working in biologically relevant problems including disease related metabolic enzymes, antibiotic resistance, DNA replication and DNA maintenance, protein synthesis, virus structure and mechanisms, and macromolecular complexes involved in the control of key cellular processes like protein folding and degradation.
DOI: 10.5281/zenodo.6982734
title: Tuomiokirjakortisto, Käkisalmen lääni, 1600-luku

description: CSV-muotoiset tiedostot Käkisalmen läänin tuomiokirjakortistoista. Lisätietoa tuomiokirjakortistoista: http://wiki.narc.fi/portti/index.php/Tuomiokirjakortisto_(Tuokko)
DOI: 10.5281/zenodo.7022629
title: Tuomiokirjakortisto, Käkisalmen lääni, 1600-luku

description: CSV-muotoiset tiedostot Käkisalmen läänin tuomiokirjakortistoista. Lisätietoa tuomiokirjakortistoista: http://wiki.narc.fi/portti/index.php/Tuomiokirjakortisto_(Tuokko)
DOI: 10.5281/zenodo.7030975
title: Tuomiokirjakortisto, Käkisalmen lääni, 1600-luku

description: CSV-muotoiset tiedostot Käkisalmen läänin tuomiokirjakortistoista. Lisätietoa tuomiokirjakortistoista: http://wiki.narc.fi/portti/index.php/Tuomiokirjakortisto_(Tuokko)
DOI: 10.5281/zenodo.7038077
title: Tuomiokirjakortisto, Käkisalmen lääni, 1600-luku

description: CSV-muotoiset tiedostot Käkisalmen läänin tuomiokirjakortistoista. Lisätietoa tuomiokirjakortistoista: http://wiki.narc.fi/portti/index.php/Tuomiokirjakortisto_(Tuokko)
DOI: 10.5281/zenodo.6982733
title: Tuomiokirjakortisto, Käkisalmen lääni, 1600-luku

description: CSV-muotoiset tiedostot Käkisalmen läänin tuomiokirjakortistoista. Lisätietoa tuomiokirjakortistoista: http://wiki.narc.fi/portti/index.php/Tuomiokirjakortisto_(Tuokko)