cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7910/dvn/8yvinu/viaoii
title: MedRed_test.txt

description: The test test with tagged entities according to the IOB tagging scheme.
DOI: 10.7910/dvn/8yvinu/4qqkt8
title: MedRed_train.txt

description: The train test with tagged entities according to the IOB tagging scheme.
DOI: 10.7910/dvn/8yvinu/wsc0ke
title: MedRed_dev.txt

description: The development test with tagged entities according to the IOB tagging scheme.
DOI: 10.6085/aa/shb001_021mxti012r00_20110127.40.1
title: (:unkn)
DOI: 10.6085/aa/shb001_021mxti012r00_20110313.40.1
title: (:unkn)
DOI: 10.6085/aa/shb001_021mxti012r00_20110422.40.1
title: (:unkn)
DOI: 10.6085/aa/shb001_021mxti012r00_20110809.40.1
title: (:unkn)
DOI: 10.6085/aa/shb001_021mxti012r00_20110906.40.1
title: (:unkn)
DOI: 10.6085/aa/shb001_021mxti012r00_20111101.40.1
title: (:unkn)
DOI: 10.14469/hpc/6912
title: 4-allyl-2-methoxyphenyl 2-cyclopentylacetate

description: 15 mL acetonitrile, DMAP(61 mg, 0.5 mmol) and EDC.HCl (1.25 g, 6.5 mmol) were mixed. 0.702 g of cyclopentylacetic acid (5.45 mmol), rinsing with 5 + 2 mL of acetonitrile. 0.819 g of eugenol (4.99 mmol) was added, rinsing with 5 + 2 mL of acetonitrile. The mixture was reacted under reflux at about 97 –99oC with stirring. TLC was conducted every 20 min with 30% ethyl acetate in hexane as the eluent to see when reaction was complete. At 65 mins the reaction was complete with a faintly yellow solution produced. When complete, after adding 20 mL hexane, the mixture was washed with HCl (1M, 2 x 20 mL), NaHCO3 (10 wt%, 2 x 20 mL), 20 mL distilled H2O and saturated NaCl(aq) (2 x 20 mL). The mixture was filtered under gravity and rinsed with 10 mL hexane after drying with MgSO4. The solvent was then removed in vacuo, leaving our synthesized ester. A slightly darker yellow solution was produced after being rotary evaporated. Product appears to be almost pure from NMR and IR analysis
DOI: 10.6073/pasta/ac0cb1045ce6a1eb35674fc6d4b9fc4b
title: Jornada Basin LTER: Wireless meteorological station at NPP C-CALI site: 30-minute summary data: 2013 - ongoing

description: 30-minute summary data at NPP C-CALI met station. Average air temperature, relative humidity, wind speed and wind direction are measured and calculated based on 1-second scan rate of all sensors located at an automated meteorological station installed at Jornada LTER NPP C-CALI site. Wind speed is measured at 75 cm, 150 cm, and 300 cm, wind direction at approximately 3m, and air temperature and relative humidity at approximate 2.5m. This climate station is operated by the Jornada LTER Program. This is an ONGOING dataset.
DOI: 10.6085/aa/shlx00_xxxibtnxtsr01_20111028.40.1
title: (:unkn)
DOI: 10.6085/aa/shlx00_xxxibtnxtsr01_20111128.40.1
title: (:unkn)
DOI: 10.6085/aa/shlx00_xxxibtnxtsr01_20120108.40.1
title: (:unkn)
DOI: 10.14469/hpc/6913
title: 4-allyl-2-methoxyphenyl 2-cyclopropylacetate

description: 15 mL acetonitrile, DMAP(61 mg, 0.5 mmol) and EDC.HCl (1.25 g, 6.5 mmol) were mixed. 0.5635 g of cyclopropylacetic acid (5.64 mmol) was added, rinsing with 5 + 2 mL of acetonitrile. 0.837 g of eugenol (5.10 mmol) was added, rinsing with 5 + 2 mL of acetonitrile. The mixture was reacted under reflux at 97–99oC with stirring. TLC was conducted every 20 min with 30% ethyl acetate in hexane as the eluent to see when reaction was complete. At 60 mins the reaction was complete with a colourless solution produced. When complete, after adding 20 mL hexane, the mixture was washed with HCl (1M, 2 x 20 mL), NaHCO3 (10 wt%, 2 x 20 mL), 20 mL distilled H2O and saturated NaCl(aq) (2 x 20 mL). The mixture was filtered under gravity and rinsed with 10 mL hexane after drying with MgSO4. The solvent was then removed in vacuo, leaving our synthesized ester. No visible change to colour after being rotary evaporated. Product not 100% pure
DOI: 10.25345/c5w993
title: MassIVE MSV000085051 - G q/11 -dependent regulation of endosomal cAMP generation by parathyroid hormone class B GPCR
title: cAMP production on activation of Gs by G protein-coupled receptors has classically been considered to be plasma membranedelimited, but a shift in this paradigm has occurred in recent years with the identification of several receptors that continue to signal from early endosomes after internalization. The molecular mechanisms regulating this aspect of signaling remain incompletely understood. Here, we investigated the role of Gq/11 activation by the parathyroid hormone (PTH) type 1 receptor (PTHR) in mediating endosomalcAMPresponses.InhibitionofGq/11 signalingbyFR900359 markedly reduced the duration of PTH-induced cAMP production, and this effect was mimicked in cells lacking endogenous Gaq/11. We determined that modulation of cAMP generation by Gq/11 occurs at the level of the heterotrimeric G protein via liberation of cell surface Gbr subunits, which, in turn, act in a phosphoinositide3 kinase dependent manner to promote the assembly of PTHR barrestinGbr signaling complexes that mediate endosomal cAMP responses. These resultsunveil insights intothe spatiotemporalregulation of Gs-dependent cAMP signaling.
DOI: 10.6073/pasta/6150397728dc4200da3b0890a2b554e5
title: Jornada Basin LTER: Wireless meteorological station at NPP C-CALI site: Daily summary data: 2013 - ongoing

description: Daily summary data at NPP C-CALI met station. Average/maximum/minimum air temperature; average/maximum relative humidity and wind speed and average wind direction. These are measured and calculated based on 1-second scan rate of all sensors located at an automated meteorological station installed at Jornada LTER NPP C-CALI site. Wind speed is measured at 75 cm, 150 cm, and 300 cm, wind direction at approximately 3m, and air temperature and relative humidity at approximate 2.5m. This climate station is operated by the Jornada LTER Program. This is an ONGOING dataset.
DOI: 10.6085/aa/shlx00_xxxibtnxmbr11_20110509.40.1
title: (:unkn)
DOI: 10.6085/aa/shb001_021mxti019r00_20110127.40.1
title: (:unkn)
DOI: 10.6085/aa/shb001_021mxti019r00_20110313.40.1
title: (:unkn)
DOI: 10.6085/aa/shb001_021mxti019r00_20110422.40.1
title: (:unkn)
DOI: 10.6085/aa/shb001_021mxti019r00_20110809.40.1
title: (:unkn)
DOI: 10.6085/aa/shb001_021mxti019r00_20110906.40.1
title: (:unkn)
DOI: 10.6085/aa/shb001_021mxti019r00_20111101.40.1
title: (:unkn)
DOI: 10.6073/pasta/1317258803df0f60445e1c0c95f09670
title: Jornada Basin LTER: Wireless meteorological station at NPP C-CALI site: 1-second summary precipitation data: 2013 - ongoing

description: 1-second summary precipitation data at NPP C-CALI met station. Total precipitation per second is recorded only if there is measurable precipitation. This is recorded at an automated meteorological station installed at Jornada LTER NPP C-CALI site.. This climate station is operated by the Jornada LTER Program. IMPORTANT: Rainfall is only recorded when a bucket tip occurs on the tipping bucket rain gauge. If there is missing data due to equipment or other problems, there will be no indication of this within this dataset. The user needs to review precipitation values in the 30 minute, hourly, or data summary datasets to determine if there are missing periods in this 1 second detailed precipitation dataset. Reference the package i.d.'s knb-lter-jrn.210437016, knb-lter-jrn.210437031, and knb-lter-jrn.210437046 for the NPP C-CALI met station 30 minute, hourly, and daily summary datasets, respectively. This is an ONGOING dataset.
DOI: 10.6085/aa/shlx00_xxxibtnxmbr12_20110616.40.1
title: (:unkn)
DOI: 10.3886/e117390v1
title: Social Heterogeneity, Local Capacity, and Urban Parks

description: Please cite the corresponding article if this dataset is used to support additional findings:<br><br>Leon-Moreta, Agustin, Vittoria R. Totaro, and David S. Dixon. "Social heterogeneity, local capacity, and urban parks: Evidence from US cities." Cities 99 (2020): 102588. https://doi.org/10.1016/j.cities.2019.102588<br><br>The data described here were used in the analysis and findings reported in the article reference above. A STATA (V. 13) do-file for calculating variables and R scripts for deriving the reported geospatial model are also included. Please cite the corresponding article if this dataset is used to support additional findings.<br><br>Note that a variable has been removed from this dataset due to proprietary interests. Please contact corresponding author Leon-Moreta for more information and access to this variable.
description: Municipalities in the United States.
DOI: 10.6084/m9.figshare.5670268
title: Determinants of the use of health care services: multilevel analysis in the Metropolitan Region of Sao Paulo

description: OBJECTIVE To evaluate the individual and contextual determinants of the use of health care services in the metropolitan region of Sao Paulo.METHODS Data from the Sao Paulo Megacity study – the Brazilian version of the World Mental Health Survey multicenter study – were used. A total of 3,588 adults living in 69 neighborhoods in the metropolitan region of Sao Paulo, SP, Southeastern Brazil, including 38 municipalities and 31 neighboring districts, were selected using multistratified sampling of the non-institutionalized population. Multilevel Bayesian logistic models were adjusted to identify the individual and contextual determinants of the use of health care services in the past 12 months and presence of a regular physician for routine care.RESULTS The contextual characteristics of the place of residence (income inequality, violence, and median income) showed no significant correlation (p &gt; 0.05) with the use of health care services or with the presence of a regular physician for routine care. The only exception was the negative correlation between living in areas with high income inequality and presence of a regular physician (OR: 0.77; 95%CI 0.60;0.99) after controlling for individual characteristics. The study revealed a strong and consistent correlation between individual characteristics (mainly education and possession of health insurance), use of health care services, and presence of a regular physician. Presence of chronic and mental illnesses was strongly correlated with the use of health care services in the past year (regardless of the individual characteristics) but not with the presence of a regular physician.CONCLUSIONS Individual characteristics including higher education and possession of health insurance were important determinants of the use of health care services in the metropolitan area of Sao Paulo. A better understanding of these determinants is essential for the development of public policies that promote equitable use of health care services.
DOI: 10.6084/m9.figshare.5670268.v1
title: Determinants of the use of health care services: multilevel analysis in the Metropolitan Region of Sao Paulo

description: OBJECTIVE To evaluate the individual and contextual determinants of the use of health care services in the metropolitan region of Sao Paulo.METHODS Data from the Sao Paulo Megacity study – the Brazilian version of the World Mental Health Survey multicenter study – were used. A total of 3,588 adults living in 69 neighborhoods in the metropolitan region of Sao Paulo, SP, Southeastern Brazil, including 38 municipalities and 31 neighboring districts, were selected using multistratified sampling of the non-institutionalized population. Multilevel Bayesian logistic models were adjusted to identify the individual and contextual determinants of the use of health care services in the past 12 months and presence of a regular physician for routine care.RESULTS The contextual characteristics of the place of residence (income inequality, violence, and median income) showed no significant correlation (p &gt; 0.05) with the use of health care services or with the presence of a regular physician for routine care. The only exception was the negative correlation between living in areas with high income inequality and presence of a regular physician (OR: 0.77; 95%CI 0.60;0.99) after controlling for individual characteristics. The study revealed a strong and consistent correlation between individual characteristics (mainly education and possession of health insurance), use of health care services, and presence of a regular physician. Presence of chronic and mental illnesses was strongly correlated with the use of health care services in the past year (regardless of the individual characteristics) but not with the presence of a regular physician.CONCLUSIONS Individual characteristics including higher education and possession of health insurance were important determinants of the use of health care services in the metropolitan area of Sao Paulo. A better understanding of these determinants is essential for the development of public policies that promote equitable use of health care services.
DOI: 10.6084/m9.figshare.5670265
title: Impact of local treatment on overall survival of patients with metastatic prostate cancer: systematic review and meta-analysis

description: ABSTRACT Context Currently, standard treatment of metastatic prostatic cancer (MPCa) is androgen-deprivation therapy (ADT). Recent studies suggested that local treatment of MPCa is related to increase of survival of those patients, as observed in other tumors. Objective To evaluate the impact of local treatment on overall survival and cancer specific survival in 3 and 5 years in patients with MPCa. Materials and Methods Systematic review and meta-analysis of population studies published at PubMed, Scielo, Lilacs, Cochrane and EMBASE databases until June 2016. Several large cohorts and Post-Roc studies were included, that evaluated patients with MPCa submitted to local treatment (LT) using radiotherapy (RDT), surgery (RP) or brachytherapy (BCT) or not submitted to local treatment (NLT). Results 34.338 patients were analyzed in six included papers, 31.653 submitted to NLT and 2.685 to LT. Overall survival in three years was significantly higher in patients submitted to LT versus NLT (64.2% vs. 44.5%; RD 0.19, 95% CI, 0.17-0.21; p&lt;0.00001; I2=0%), as well as in five years (51.9% vs. 23.6%; RD 0.30, 95% CI, 0.11-0.49; p&lt;0.00001; I2=97%). Sensitive analysis according to type of local treatment showed that surgery (78.2% and 45.0%; RD 0.31, 95% CI, 0.26-0.35; p&lt;0.00001; I2=50%) and radiotherapy (60.4% and 44.5%; RD 0.17, 95% CI, 0.12-0.22; p&lt;0.00001; I2=67%) presented better outcomes. Conclusion LT using RDT, RP or BCT seems to significantly improve overall survival and cancer-specific survival of patients with metastatic prostatic cancer. Prospective and randomized studies must be performed in order to confirm our results.
DOI: 10.6084/m9.figshare.5670265.v1
title: Impact of local treatment on overall survival of patients with metastatic prostate cancer: systematic review and meta-analysis

description: ABSTRACT Context Currently, standard treatment of metastatic prostatic cancer (MPCa) is androgen-deprivation therapy (ADT). Recent studies suggested that local treatment of MPCa is related to increase of survival of those patients, as observed in other tumors. Objective To evaluate the impact of local treatment on overall survival and cancer specific survival in 3 and 5 years in patients with MPCa. Materials and Methods Systematic review and meta-analysis of population studies published at PubMed, Scielo, Lilacs, Cochrane and EMBASE databases until June 2016. Several large cohorts and Post-Roc studies were included, that evaluated patients with MPCa submitted to local treatment (LT) using radiotherapy (RDT), surgery (RP) or brachytherapy (BCT) or not submitted to local treatment (NLT). Results 34.338 patients were analyzed in six included papers, 31.653 submitted to NLT and 2.685 to LT. Overall survival in three years was significantly higher in patients submitted to LT versus NLT (64.2% vs. 44.5%; RD 0.19, 95% CI, 0.17-0.21; p&lt;0.00001; I2=0%), as well as in five years (51.9% vs. 23.6%; RD 0.30, 95% CI, 0.11-0.49; p&lt;0.00001; I2=97%). Sensitive analysis according to type of local treatment showed that surgery (78.2% and 45.0%; RD 0.31, 95% CI, 0.26-0.35; p&lt;0.00001; I2=50%) and radiotherapy (60.4% and 44.5%; RD 0.17, 95% CI, 0.12-0.22; p&lt;0.00001; I2=67%) presented better outcomes. Conclusion LT using RDT, RP or BCT seems to significantly improve overall survival and cancer-specific survival of patients with metastatic prostatic cancer. Prospective and randomized studies must be performed in order to confirm our results.
DOI: 10.6084/m9.figshare.5670262
title: Advances and challenges in oral health after a decade of the “Smiling Brazil” Program

description: ABSTRACT OBJECTIVE To analyze oral health work changes in primary health care after Brazil’s National Oral Health Policy Guidelines were released. METHODS A literature review was conducted on Medline, LILACS, Embase, SciELO, Biblioteca Virtual em Saúde, and The Cochrane Library databases, from 2000 to 2013, on elements to analyze work changes. The descriptors used included: primary health care, family health care, work, health care policy, oral health care services, dentistry, oral health, and Brazil. Thirty-two studies were selected and analyzed, with a predominance of qualitative studies from the Northeast region with workers, especially dentists, focusing on completeness and quality of care. RESULTS Observed advances focused on educational and permanent education actions; on welcoming, bonding, and accountability. The main challenges were related to completeness; extension and improvement of care; integrated teamwork; working conditions; planning, monitoring, and evaluation of actions; stimulating people’s participation and social control; and intersectorial actions. CONCLUSIONS Despite the new regulatory environment, there are very few changes in oral health work. Professionals tend to reproduce the dominant biomedical model. Continuing efforts will be required in work management, training, and permanent education fields. Among the possibilities are the increased engagement of managers and professionals in a process to understand work dynamics and training in the perspective of building significant changes for local realities.
DOI: 10.6084/m9.figshare.5670259
title: Methods and challenges for the health impact assessment of vaccination programs in Latin America

description: ABSTRACT OBJECTIVE To describe methods and challenges faced in the health impact assessment of vaccination programs, focusing on the pneumococcal conjugate and rotavirus vaccines in Latin America and the Caribbean. METHODS For this narrative review, we searched for the terms "rotavirus", "pneumococcal", "conjugate vaccine", "vaccination", "program", and "impact" in the databases Medline and LILACS. The search was extended to the grey literature in Google Scholar. No limits were defined for publication year. Original articles on the health impact assessment of pneumococcal and rotavirus vaccination programs in Latin America and the Caribbean in English, Spanish or Portuguese were included. RESULTS We identified 207 articles. After removing duplicates and assessing eligibility, we reviewed 33 studies, 25 focusing on rotavirus and eight on pneumococcal vaccination programs. The most frequent studies were ecological, with time series analysis or comparing pre- and post-vaccination periods. The main data sources were: health information systems; population-, sentinel- or laboratory-based surveillance systems; statistics reports; and medical records from one or few health care services. Few studies used primary data. Hospitalization and death were the main outcomes assessed. CONCLUSIONS Over the last years, a significant number of health impact assessments of pneumococcal and rotavirus vaccination programs have been conducted in Latin America and the Caribbean. These studies were carried out few years after the programs were implemented, meet the basic methodological requirements and suggest positive health impact. Future assessments should consider methodological issues and challenges arisen in these first studies conducted in the region.
DOI: 10.6084/m9.figshare.5670262.v1
title: Advances and challenges in oral health after a decade of the “Smiling Brazil” Program

description: ABSTRACT OBJECTIVE To analyze oral health work changes in primary health care after Brazil’s National Oral Health Policy Guidelines were released. METHODS A literature review was conducted on Medline, LILACS, Embase, SciELO, Biblioteca Virtual em Saúde, and The Cochrane Library databases, from 2000 to 2013, on elements to analyze work changes. The descriptors used included: primary health care, family health care, work, health care policy, oral health care services, dentistry, oral health, and Brazil. Thirty-two studies were selected and analyzed, with a predominance of qualitative studies from the Northeast region with workers, especially dentists, focusing on completeness and quality of care. RESULTS Observed advances focused on educational and permanent education actions; on welcoming, bonding, and accountability. The main challenges were related to completeness; extension and improvement of care; integrated teamwork; working conditions; planning, monitoring, and evaluation of actions; stimulating people’s participation and social control; and intersectorial actions. CONCLUSIONS Despite the new regulatory environment, there are very few changes in oral health work. Professionals tend to reproduce the dominant biomedical model. Continuing efforts will be required in work management, training, and permanent education fields. Among the possibilities are the increased engagement of managers and professionals in a process to understand work dynamics and training in the perspective of building significant changes for local realities.
DOI: 10.6084/m9.figshare.5670259.v1
title: Methods and challenges for the health impact assessment of vaccination programs in Latin America

description: ABSTRACT OBJECTIVE To describe methods and challenges faced in the health impact assessment of vaccination programs, focusing on the pneumococcal conjugate and rotavirus vaccines in Latin America and the Caribbean. METHODS For this narrative review, we searched for the terms "rotavirus", "pneumococcal", "conjugate vaccine", "vaccination", "program", and "impact" in the databases Medline and LILACS. The search was extended to the grey literature in Google Scholar. No limits were defined for publication year. Original articles on the health impact assessment of pneumococcal and rotavirus vaccination programs in Latin America and the Caribbean in English, Spanish or Portuguese were included. RESULTS We identified 207 articles. After removing duplicates and assessing eligibility, we reviewed 33 studies, 25 focusing on rotavirus and eight on pneumococcal vaccination programs. The most frequent studies were ecological, with time series analysis or comparing pre- and post-vaccination periods. The main data sources were: health information systems; population-, sentinel- or laboratory-based surveillance systems; statistics reports; and medical records from one or few health care services. Few studies used primary data. Hospitalization and death were the main outcomes assessed. CONCLUSIONS Over the last years, a significant number of health impact assessments of pneumococcal and rotavirus vaccination programs have been conducted in Latin America and the Caribbean. These studies were carried out few years after the programs were implemented, meet the basic methodological requirements and suggest positive health impact. Future assessments should consider methodological issues and challenges arisen in these first studies conducted in the region.