cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17632/jy4jw2hhvg.2
title: Survey data on the Effect of Macro-economic Factors on Business Sustainability in the Leather Industry Cluster of Kanpur and Unnao, Uttar Pradesh , India

description: Macro-economic factors are known to significantly affect the business performance. Kanpur and Unnao, situated on the river Ganges have evolved as the leather industry hub of North India. Leather Industry is known to pollute surface and groundwater resources and chromium pollution is known to take its toll on the workers in the leather processing and tanning. Pollutants and waste water invariably finds its way to the River Ganges. Recent environmental consciousness and changes in ethical consumption of leather goods have motivated the researchers to investigate the effects of macro-economic factors on the business sustainability of the leather industry. 500 industry workers, manufacturers, raw hide suppliers, marketers and exporters were presented with a questionnaire comprising nine demographic and 42 items, six each the seven constructs used in the study. The data was collected in a face to face setting where the potential respondents were explained the purpose of the study and their consent was taken before collecting the data. No personally identifiable information was collected and participation was voluntary. The final data of 397 comprised mostly of males (93.2%). 7 point Likert type questions were framed to elicit responses on the seven constructs namely, Government Policies & Regulations, Environmental Regulations, Economic Conditions, Technological Advancements, Socio-Cultural Factors, Global Market Trends and Business Sustainability.
The preliminary data was analysed using SPSS 23 and the hypotheses were analysed using path analysis by structural equation modelling (SmartPLS 4.0). Bootstrapping was done (10000 iterations) and the bootstrapped histograms of the path coefficients satisfactorily followed normal distribution.
Data in .xlsx and .sav formats is appended. Also included are the questionnaire, consent form and the output of PLS model.
DOI: 10.17632/79cx4pmxg4
title: Osteopontin Derived from PDE12-Driven Tumor Cells Contributes to the Immunosuppressive Niche via Triggering Inflammatory Cytokine-enriched Tumor- associated Macrophages in intrahepatic Cholangiocarcinoma

description: This data is the original dataset for Osteopontin Derived from PDE12-Driven Tumor Cells Contributes to the Immunosuppressive Niche via Triggering Inflammatory Cytokine-enriched Tumor- associated Macrophages in intrahepatic Cholangiocarcinoma. The complex intratumoral immune status is an important feature of intrahepatic cholangiocarcinoma（ICC）that has been closely connected with poor Immunotherapy response. Phosphodiesterase12 (PDE12) is identified as a significant target involved in negatively regulating the immune response, whereas its regulatory mechanism and roles in neoplasm progression remain indistinct. Herein, we show that PDE12 fuels ICC tumor growth by constructing an intratumoral immunosuppressive microenvironment (TIME). Mechanistically, the residue K377 of PDE12, competitively succinylation and de-succinylation modified by OGDH and SIRT7, is essential for its proteolytic activity. Osteopontin (OPN/SPP1), secreted by PDE12-driven ICC cells, mobilizes externalization of ANXA1 on the membrane of macrophages and accumulates inflammatory cytokine-enriched tumor- associated macrophages (Inflam-TAMs), which are responsible for the tumor-promoting effects. Underscoring the translational potential of the PDE12-SPP1-ANXA1 signaling axis, PDE12 inhibitors (PDE12-IN-1) or α-SPP1 both enhance the sensitivity of ICC cells to α-PD1 with improved anti-tumor benefits. Collectively, our findings highlight a link between ICC TIME and PDE12-SPP1-ANXA1 axis, suggesting a potentially valuable biomarker and promising therapy target for further development.
DOI: 10.17632/79cx4pmxg4.1
title: Osteopontin Derived from PDE12-Driven Tumor Cells Contributes to the Immunosuppressive Niche via Triggering Inflammatory Cytokine-enriched Tumor- associated Macrophages in intrahepatic Cholangiocarcinoma

description: This data is the original dataset for Osteopontin Derived from PDE12-Driven Tumor Cells Contributes to the Immunosuppressive Niche via Triggering Inflammatory Cytokine-enriched Tumor- associated Macrophages in intrahepatic Cholangiocarcinoma. The complex intratumoral immune status is an important feature of intrahepatic cholangiocarcinoma（ICC）that has been closely connected with poor Immunotherapy response. Phosphodiesterase12 (PDE12) is identified as a significant target involved in negatively regulating the immune response, whereas its regulatory mechanism and roles in neoplasm progression remain indistinct. Herein, we show that PDE12 fuels ICC tumor growth by constructing an intratumoral immunosuppressive microenvironment (TIME). Mechanistically, the residue K377 of PDE12, competitively succinylation and de-succinylation modified by OGDH and SIRT7, is essential for its proteolytic activity. Osteopontin (OPN/SPP1), secreted by PDE12-driven ICC cells, mobilizes externalization of ANXA1 on the membrane of macrophages and accumulates inflammatory cytokine-enriched tumor- associated macrophages (Inflam-TAMs), which are responsible for the tumor-promoting effects. Underscoring the translational potential of the PDE12-SPP1-ANXA1 signaling axis, PDE12 inhibitors (PDE12-IN-1) or α-SPP1 both enhance the sensitivity of ICC cells to α-PD1 with improved anti-tumor benefits. Collectively, our findings highlight a link between ICC TIME and PDE12-SPP1-ANXA1 axis, suggesting a potentially valuable biomarker and promising therapy target for further development.
DOI: 10.5284/1133955
title: Data from a Magnetometry Survey at Thornton Manor, Stratford-upon-Avon, Warwickshire, October 2023

description: This collection includes a report, geophysics, vector and GIS data from a magnetometer survey carried out by SUMO Geophysics at Thornton Manor, Stratford-upon-Avon, Warwickshire in October 2023.
DOI: 10.15468/dl.7c3wc2
title: Occurrence Download

description: A dataset containing 16 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Echium simplex",
 "Country is Australia",
 "HasCoordinate is true"
 ]
}

 The dataset includes 16 records from 2 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0002414-250710112747441/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.prp9vh
title: Occurrence Download

description: A dataset containing 23 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Watersipora arcuata",
 "Country is Australia",
 "HasCoordinate is true"
 ]
}

 The dataset includes 23 records from 6 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0002415-250710112747441/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.17632/5ngx4jz7fg
title: Data Repository: An aptasensor for specific quantification of the signaling protein Amuc_1100 from Akkermansia muciniphila MucT

description: The combination of rGO-FETs (reduced Graphene Oxide-Field Effect Transistor) and DNA oligonucleotide aptamers has proved to be a promising technical method to detect analytes with high sensitivity and specificity. Targeting the Amuc_1100 protein, we demonstrate the application and ability of the aptamer/FET combination to detect Akkermansia muciniphila, an intestinal symbiont that improves host metabolism. Amuc_1100, a protein highly expressed on the bacterial outer membrane that signals to Toll-like receptor 2 and, has been shown to partially replicate these beneficial effects. By developing, characterizing, and demonstrating the suitability of SELEX based anti-AMUC_1100 aptamer libraries for the construction of functional rGO-FET sensors for specific and sensitive Amuc_1100 quantification, we provide evidence that the evolution of focused polyclonal aptamer libraries for related targets can be used as a straightforward strategy. Revolution and innovation in sensing technology will undoubtedly further improve the diagnostic and monitoring process in biomedical technlogy.
DOI: 10.17632/5ngx4jz7fg.1
title: Data Repository: An aptasensor for specific quantification of the signaling protein Amuc_1100 from Akkermansia muciniphila MucT

description: The combination of rGO-FETs (reduced Graphene Oxide-Field Effect Transistor) and DNA oligonucleotide aptamers has proved to be a promising technical method to detect analytes with high sensitivity and specificity. Targeting the Amuc_1100 protein, we demonstrate the application and ability of the aptamer/FET combination to detect Akkermansia muciniphila, an intestinal symbiont that improves host metabolism. Amuc_1100, a protein highly expressed on the bacterial outer membrane that signals to Toll-like receptor 2 and, has been shown to partially replicate these beneficial effects. By developing, characterizing, and demonstrating the suitability of SELEX based anti-AMUC_1100 aptamer libraries for the construction of functional rGO-FET sensors for specific and sensitive Amuc_1100 quantification, we provide evidence that the evolution of focused polyclonal aptamer libraries for related targets can be used as a straightforward strategy. Revolution and innovation in sensing technology will undoubtedly further improve the diagnostic and monitoring process in biomedical technlogy.
DOI: 10.17632/txyzcd78pt
title: LINF_230017900

description: Protein of unknown function - conserved; Leishmania infantum (strain JPCM5)
DOI: 10.17632/txyzcd78pt.1
title: LINF_230017900

description: Protein of unknown function - conserved; Leishmania infantum (strain JPCM5)
DOI: 10.17632/53bd9d3365
title: LINF_230018200

description: Protein of unknown function - conserved; Leishmania infantum (strain JPCM5)
DOI: 10.17632/53bd9d3365.1
title: LINF_230018200

description: Protein of unknown function - conserved; Leishmania infantum (strain JPCM5)
DOI: 10.17632/xkfgsph4hw
title: LINF_230019000

description: Protein of unknown function - conserved; Leishmania infantum (strain JPCM5)
DOI: 10.17632/xkfgsph4hw.1
title: LINF_230019000

description: Protein of unknown function - conserved; Leishmania infantum (strain JPCM5)
DOI: 10.17632/4kk8cnstm6
title: Raw Data_Technology Readiness and Adoption Patterns in Indonesia's Mobile Fitness Ecosystem

description: The attachment files are the data's of the paper: Technology Readiness and Adoption Patterns in Indonesia's Mobile Fitness Ecosystem
DOI: 10.17632/4kk8cnstm6.1
title: Raw Data_Technology Readiness and Adoption Patterns in Indonesia's Mobile Fitness Ecosystem

description: The attachment files are the data's of the paper: Technology Readiness and Adoption Patterns in Indonesia's Mobile Fitness Ecosystem
DOI: 10.17632/422dvvgxz7
title: Formation of five-fold Mg complex in bicarbonate-sulfate solution facilitates inorganic precipitation of proto-dolomite at 20℃

description: TEM pictures of proto-dolomite
DOI: 10.17632/422dvvgxz7.1
title: Formation of five-fold Mg complex in bicarbonate-sulfate solution facilitates inorganic precipitation of proto-dolomite at 20℃

description: TEM pictures of proto-dolomite
DOI: 10.17632/f6r5xj9hxp
title: Locations and Storage Coefficients of Large Italian Reservoirs

description: The Dataset provides the geographic coordinates (latitude N, longitude E; WGS84) and the storage coefficient of 448 large Italian reservoirs. The storage coefficient (k) is defined as the ratio between the maximum volume above the spillway crest and the maximum discharge from the spillway (i.e., design discharge), and is expressed in hours.
DOI: 10.17632/f6r5xj9hxp.1
title: Locations and Storage Coefficients of Large Italian Reservoirs

description: The Dataset provides the geographic coordinates (latitude N, longitude E; WGS84) and the storage coefficient of 448 large Italian reservoirs. The storage coefficient (k) is defined as the ratio between the maximum volume above the spillway crest and the maximum discharge from the spillway (i.e., design discharge), and is expressed in hours.
DOI: 10.15468/dl.6v9vu4
title: Occurrence Download

description: A dataset containing 2746 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Carduus pycnocephalus",
 "Country is Australia",
 "HasCoordinate is true"
 ]
}

 The dataset includes 2746 records from 27 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0002416-250710112747441/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.17632/zmdyh4yrpg
title: SmSPI_colabfold

description: Source data and results for ColabFold simulations between Schistosoma mansoni serine protease inhibitor SmSPI and relevant human proteases
DOI: 10.15468/dl.5bzuak
title: Occurrence Download

description: A dataset containing 1397 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Misgurnus anguillicaudatus",
 "Country is Australia",
 "HasCoordinate is true"
 ]
}

 The dataset includes 1397 records from 18 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0002418-250710112747441/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.17632/zmdyh4yrpg.1
title: SmSPI_colabfold

description: Source data and results for ColabFold simulations between Schistosoma mansoni serine protease inhibitor SmSPI and relevant human proteases
DOI: 10.17632/7j8kkrg7fv
title: Divergent pathways of soil organic carbon sequestration mediated by ecological restoration in arid coal mining areas: Plant- vs. microbial-derived contributions

description: Divergent pathways of soil organic carbon sequestration mediated by ecological restoration in arid coal mining areas: Plant- vs. microbial-derived contributions
DOI: 10.17632/7j8kkrg7fv.1
title: Divergent pathways of soil organic carbon sequestration mediated by ecological restoration in arid coal mining areas: Plant- vs. microbial-derived contributions

description: Divergent pathways of soil organic carbon sequestration mediated by ecological restoration in arid coal mining areas: Plant- vs. microbial-derived contributions
DOI: 10.15468/dl.e55u8f
title: Occurrence Download

description: A dataset containing 253 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is China",
 "TaxonKey is Eothenomys miletus"
 ]
}

 The dataset includes 253 records from 8 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0002419-250710112747441/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.17632/y73n6gfcy2
title: Isolation and Immunomodulatory Evaluation of Glycyrrhiza Polysaccharide-Induced Probiotics from Murine Gut Microbiota

description: While low-molecular-weight Glycyrrhiza polysaccharide (LGP) demonstrates immunomodulatory effects through gut microbiota modulation, the specific LGP-responsive bacterial taxa and their therapeutic potential as next-generation probiotics (NGPs) remain poorly characterized. In this study, we isolated dominant LGP-induced bacterial strains (Bacteroides vulgatus and Parabacteroides sp.) from murine intestinal contents and systematically evaluated their probiotic potential using comprehensive NGPs selection criteria: 1) it has excellent gastrointestinal tolerance, and the survival rate in gastric juice with pH 2.5 and 0.5% cholate is over 90%; 2) broad-spectrum antibiotic susceptibility; 3) potent pathogen inhibition (Escherichia coli, Enterobacter cloacae, and Proteus vulgaris), and 4) absence of cytotoxicity or phagocytic interference in RAW264.7 macrophages (confirmed for heat-killed cells, supernatants, and lysates). In vivo experiments, we found that NGPs exhibited significant immunomodulatory abilities, B. vulgatus fresh culture (BX) stimulated 2.49-fold leukocyte proliferation, and parabacteroides sp. lysate (PL) elevated IL-10 production (1.33-fold). NGPs slao ameliorated hepatic injury markers, restored intestinal barrier integrity, enriched beneficial taxa (Akkermansia, Rikenella, UCG-010), enhanced SCFA production (isobutyrate, isovalerate, butyrate, valerate), and modulated critical metabolic pathways (LPS biosynthesis, TCA cycle, gluconeogenesis). These findings not only elucidate the microbial mechanisms underlying LGP's immunomodulation but also provide two well-characterized, gut-derived NGP candidates with validated multi-functional efficacy, meeting stringent safety and functionality requirements for therapeutic development.
DOI: 10.17632/y73n6gfcy2.1
title: Isolation and Immunomodulatory Evaluation of Glycyrrhiza Polysaccharide-Induced Probiotics from Murine Gut Microbiota

description: While low-molecular-weight Glycyrrhiza polysaccharide (LGP) demonstrates immunomodulatory effects through gut microbiota modulation, the specific LGP-responsive bacterial taxa and their therapeutic potential as next-generation probiotics (NGPs) remain poorly characterized. In this study, we isolated dominant LGP-induced bacterial strains (Bacteroides vulgatus and Parabacteroides sp.) from murine intestinal contents and systematically evaluated their probiotic potential using comprehensive NGPs selection criteria: 1) it has excellent gastrointestinal tolerance, and the survival rate in gastric juice with pH 2.5 and 0.5% cholate is over 90%; 2) broad-spectrum antibiotic susceptibility; 3) potent pathogen inhibition (Escherichia coli, Enterobacter cloacae, and Proteus vulgaris), and 4) absence of cytotoxicity or phagocytic interference in RAW264.7 macrophages (confirmed for heat-killed cells, supernatants, and lysates). In vivo experiments, we found that NGPs exhibited significant immunomodulatory abilities, B. vulgatus fresh culture (BX) stimulated 2.49-fold leukocyte proliferation, and parabacteroides sp. lysate (PL) elevated IL-10 production (1.33-fold). NGPs slao ameliorated hepatic injury markers, restored intestinal barrier integrity, enriched beneficial taxa (Akkermansia, Rikenella, UCG-010), enhanced SCFA production (isobutyrate, isovalerate, butyrate, valerate), and modulated critical metabolic pathways (LPS biosynthesis, TCA cycle, gluconeogenesis). These findings not only elucidate the microbial mechanisms underlying LGP's immunomodulation but also provide two well-characterized, gut-derived NGP candidates with validated multi-functional efficacy, meeting stringent safety and functionality requirements for therapeutic development.
DOI: 10.17632/5y7jdmw4yy
title: Spectrophotometry Uv-Vis and TLC Data for Phytochemical of Ethanolic Extract Moringa oleifera

description: The UV-Visible spectrophotometric analysis of Moringa oleifera extract revealed characteristic absorption peaks indicating the presence of phenol, flavonoid, alkaloid, tannin, and saponin compounds, while Thin Layer Chromatography (TLC) profiling steroids and terpenoids.
DOI: 10.17632/5y7jdmw4yy.1
title: Spectrophotometry Uv-Vis and TLC Data for Phytochemical of Ethanolic Extract Moringa oleifera

description: The UV-Visible spectrophotometric analysis of Moringa oleifera extract revealed characteristic absorption peaks indicating the presence of phenol, flavonoid, alkaloid, tannin, and saponin compounds, while Thin Layer Chromatography (TLC) profiling steroids and terpenoids.
DOI: 10.15468/dl.crgy5v
title: Occurrence Download

description: A dataset containing 484014 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Cenchrus spinifex, Chloris gayana, Cynara cardunculus, Erigeron canadensis, Oenothera laciniata, Tetragonia tetragonoides, Acacia crassicarpa, Acanthospermum australe, Aeschynomene americana, Agave vivipara)",
 "BasisOfRecord is one of (Specimen, Human Observation, Observation, Living Specimen, Machine Observation, Literature Occurrence)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 484014 records from 2845 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0002409-250710112747441/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.cqm9k8
title: Occurrence Download

description: A dataset containing 129 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Caracal aurata"
 ]
}

 The dataset includes 129 records from 8 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0010781-251025141854904/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.vkea8s
title: Occurrence Download

description: A dataset containing 1 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Betta tomi",
 "Country is Singapore",
 "OccurrenceStatus is Present",
 "EventDate is 1800,2026"
 ]
}

 The dataset includes 1 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0010782-251025141854904/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.17501780
title: Python Codes and Some Data Files Supporting "Deep learning-based diagnosis of corneal condition by using raw optical coherence tomography data"
DOI: 10.6084/m9.figshare.29886833
title: <b>Genetic Studies in Carrot (</b><i>Daucus carota </i><b> </b>L.<b>): Advancements and Trends in Research</b>

description: Cultivated carrot (Daucus carota L. subsp. <i>sativus</i>) is a globally important crop, valued both economically and nutritionally for its high content of beta-carotene, vitamins, and other bioactive compounds. Advances in molecular genetics and genomics have significantly contributed to carrot breeding, enhancing traits such as yield, stress tolerance, disease resistance, pigment content (carotenoids and anthocyanins), and nutritional quality. This study provides a comprehensive scientometric analysis of genetic research on carrots, mapping trends, and identifying main research themes and methodological developments from 1960 to 2023. Through bibliometric analysis of 398 publications indexed in Web of Science, using keyword co-occurrence networks, author collaboration patterns, and temporal trend analysis. Three distinct research phases were identified: an initial exploratory phase (1964-1989), a growth phase driven by molecular marker development (1990-2009), and a modern acceleration phase (2010-2023) characterized by next-generation sequencing and genome-wide association studies. Research focus was predominantly on Plant Biology (67.59%), followed by Conservation (15.58%) and Plant Breeding (10.55%). The integration of omics technologies has provided new insights into abiotic stress tolerance, carotenoid and anthocyanin biosynthesis, and genetic diversity. Despite significant advancements, challenges remain in integrating genomic resources into breeding programs and ensuring genetic diversity conservation. Future research should emphasize genome-assisted breeding strategies and functional genomics for sustainable carrot production under climate change.