cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.6207827.v1
title: First stages chronic kidney disease have mild effects on cognitive performance. Results of a 15,105 brazilian adult baseline cohort

description: Abstract Introduction: The aging of the population may lead to an increased prevalence of dementia and chronic kidney disease (CKD) and their overlap. Objective: We investigated the association between CKD and cognitive performance among Brazilian adults (35-74 years). Methods: Baseline data analysis of the Longitudinal Study of Adults (ELSA-Brasil), a multicenter cohort comprising 15,105 civil servants, was performed. Kidney function was defined by the CKD-Epi-estimated GRF and albumin creatinin ratio (ACR). Cognitive performance was measured across tests that included the word memory tests, verbal fluency tests and Trail Making Test B. Multiple logistic and linear regressions were used to investigate the association between CKD and global as well as test-specific lowered cognitive performance. Results: More than 90% of participants did not present CKD even considering reduced GFR or increased ACR simultaneously. Lowered cognitive performance was detected among 15.8% of the participants and mean values of GFR were slightly higher among those with normal than with lowered cognitive performance (86 ± 15 mL/min/1.73 m2 x 85 ± 16 mL/min/1.73 m2, p &lt; 0.01). Age, education, skin-color, smoking, drinking, hypertension, and diabetes were associated with lowered cognition. After adjustment for these variables, there was no association between CKD and lowered cognitive performance. Negligibly small beta values were observed when analyzing CKD and the scores of all tests. Conclusion: These results suggest that cognitive performance remains preserved until renal function reaches significant worsening. Preventive measures to maintain renal function may contribute to the preservation of cognitive function.
DOI: 10.6084/m9.figshare.6207806
title: Sugarcane bagasse as a source of carbon for enzyme production by filamentous fungi1

description: ABSTRACT The aim of the present work was to assess the enzymatic activity of six strains of filamentous fungi grown in liquid media containing 1% sugarcane bagasse as the sole carbon source. All fungal strains were able to use this agro-industrial residue, producing various types of enzymes, such as cellulases, xylanases, amylases, pectinases, and laccases. However, Aspergillus japonicus Saito was the most efficient producer, showing the highest enzymatic activity for laccase (395.73 U L-1), endo-β-1,4-xylanase (3.55 U mL-1) and β-xylosidase (9.74 U mL-1) at seven, fourteen and twenty-one days in culture, respectively. Furthermore, the endo-β-1,4-xylanases and β-xylosidases of A. japonicus showed maximum activity at 50°C, and pH 5.5 and pH 3.5-4.5, respectively. Thus, these results indicate that A. japonicus has a great biotechnological potential for the production of these enzymes using sugarcane bagasse as the sole source of carbon.
DOI: 10.6084/m9.figshare.6207806.v1
title: Sugarcane bagasse as a source of carbon for enzyme production by filamentous fungi1

description: ABSTRACT The aim of the present work was to assess the enzymatic activity of six strains of filamentous fungi grown in liquid media containing 1% sugarcane bagasse as the sole carbon source. All fungal strains were able to use this agro-industrial residue, producing various types of enzymes, such as cellulases, xylanases, amylases, pectinases, and laccases. However, Aspergillus japonicus Saito was the most efficient producer, showing the highest enzymatic activity for laccase (395.73 U L-1), endo-β-1,4-xylanase (3.55 U mL-1) and β-xylosidase (9.74 U mL-1) at seven, fourteen and twenty-one days in culture, respectively. Furthermore, the endo-β-1,4-xylanases and β-xylosidases of A. japonicus showed maximum activity at 50°C, and pH 5.5 and pH 3.5-4.5, respectively. Thus, these results indicate that A. japonicus has a great biotechnological potential for the production of these enzymes using sugarcane bagasse as the sole source of carbon.
DOI: 10.6084/m9.figshare.6207803
title: Hematological response of Amazonian ornamental Peckoltia oligospila subjected to stress by transportation

description: ABSTRACT The objective of this work was to evaluate the hematological responses of bola-pleco (Peckoltia oligospila) undergoing the stress of transportation. Variations on blood parameters were analyzed at 0, 6, 24, 48, 72 and 96h after transportation. Responses to stress were detected from 0 to 6h after the transportation of fish, however, most parameters returned to baselines values within 24h of transportation. The moment of 0h was the most critical, presenting higher values of glycemia, erythroblasts and erythrocytes. Late secondary responses were observed to total plasmatic protein, mean corpuscular volume (MCV) and mean corpuscular hemoglobin (MCH) at 6h, returning to baselines values after this time. Leukocyte number was not affected by stress of transportation. The stress by transportation was not severe to influence the health of P. oligospila, indicating that fish is resistant to stress if compared to other species. However, we recommended no stressful procedures for at least 24 hours for recovery, in order to ensure health and survival of fish.
DOI: 10.6084/m9.figshare.6207803.v1
title: Hematological response of Amazonian ornamental Peckoltia oligospila subjected to stress by transportation

description: ABSTRACT The objective of this work was to evaluate the hematological responses of bola-pleco (Peckoltia oligospila) undergoing the stress of transportation. Variations on blood parameters were analyzed at 0, 6, 24, 48, 72 and 96h after transportation. Responses to stress were detected from 0 to 6h after the transportation of fish, however, most parameters returned to baselines values within 24h of transportation. The moment of 0h was the most critical, presenting higher values of glycemia, erythroblasts and erythrocytes. Late secondary responses were observed to total plasmatic protein, mean corpuscular volume (MCV) and mean corpuscular hemoglobin (MCH) at 6h, returning to baselines values after this time. Leukocyte number was not affected by stress of transportation. The stress by transportation was not severe to influence the health of P. oligospila, indicating that fish is resistant to stress if compared to other species. However, we recommended no stressful procedures for at least 24 hours for recovery, in order to ensure health and survival of fish.
DOI: 10.6084/m9.figshare.6207800
title: ETHNOGRAPHY AND ITS CONTRIBUTIONS TO THE DEVELOPMENT OF A RESEARCH IN THE TEACHING CONTEXT OF THE PEDAGOGY OF ALTERNATION

description: ABSTRACT In this paper, we analyse the ethnography contributions to the development of a research in a school named Escola Família Agrícola (EFA). As it is an ethnographic research, we have been adopted the qualitative and interpretative approach in data analysis, because the study focus are the literacy practices and events mediated by the pedagogical tools of the Pedagogy of Alternation. The data were generated in 2014 and consist of: audio-visual material, field notes, school documents, photographs and texts of (16) the genre Notebook of Reality. Considering the didactic-pedagogical proposal of the teaching context of the Pedagogy of Alternation had assumed by the school and the teachers' work, the research results have revealed that the students training makes it possible to develop language skills from the social uses of writing at school and in the community.
DOI: 10.6084/m9.figshare.6207800.v1
title: ETHNOGRAPHY AND ITS CONTRIBUTIONS TO THE DEVELOPMENT OF A RESEARCH IN THE TEACHING CONTEXT OF THE PEDAGOGY OF ALTERNATION

description: ABSTRACT In this paper, we analyse the ethnography contributions to the development of a research in a school named Escola Família Agrícola (EFA). As it is an ethnographic research, we have been adopted the qualitative and interpretative approach in data analysis, because the study focus are the literacy practices and events mediated by the pedagogical tools of the Pedagogy of Alternation. The data were generated in 2014 and consist of: audio-visual material, field notes, school documents, photographs and texts of (16) the genre Notebook of Reality. Considering the didactic-pedagogical proposal of the teaching context of the Pedagogy of Alternation had assumed by the school and the teachers' work, the research results have revealed that the students training makes it possible to develop language skills from the social uses of writing at school and in the community.
DOI: 10.6084/m9.figshare.6207791
title: The differentiation potential of adipose tissue-derived mesenchymal stem cells into cell lineage related to male germ cells

description: ABSTRACT The adipose tissue is a reliable source of Mesenchymal stem cells (MSCs) showing a higher plasticity and transdifferentiation potential into multilineage cells. In the present study, adipose tissue-derived mesenchymal stem cells (AT-MSCs) were isolated from mice omentum and epididymis fat depots. The AT-MSCs were initially compared based on stem cell surface markers and on the mesodermal trilineage differentiation potential. Additionally, AT-MSCs, from both sources, were cultured with differentiation media containing retinoic acid (RA) and/or testicular cell-conditioned medium (TCC). The AT-MSCs expressed mesenchymal surface markers and differentiated into adipogenic, chondrogenic and osteogenic lineages. Only omentum-derived AT-MSCs expressed one important gene marker related to male germ cell lineages, after the differentiation treatment with RA. These findings reaffirm the importance of adipose tissue as a source of multipotent stromal-stem cells, as well as, MSCs source regarding differentiation purpose.
DOI: 10.6084/m9.figshare.6207791.v1
title: The differentiation potential of adipose tissue-derived mesenchymal stem cells into cell lineage related to male germ cells

description: ABSTRACT The adipose tissue is a reliable source of Mesenchymal stem cells (MSCs) showing a higher plasticity and transdifferentiation potential into multilineage cells. In the present study, adipose tissue-derived mesenchymal stem cells (AT-MSCs) were isolated from mice omentum and epididymis fat depots. The AT-MSCs were initially compared based on stem cell surface markers and on the mesodermal trilineage differentiation potential. Additionally, AT-MSCs, from both sources, were cultured with differentiation media containing retinoic acid (RA) and/or testicular cell-conditioned medium (TCC). The AT-MSCs expressed mesenchymal surface markers and differentiated into adipogenic, chondrogenic and osteogenic lineages. Only omentum-derived AT-MSCs expressed one important gene marker related to male germ cell lineages, after the differentiation treatment with RA. These findings reaffirm the importance of adipose tissue as a source of multipotent stromal-stem cells, as well as, MSCs source regarding differentiation purpose.
DOI: 10.6084/m9.figshare.6207788
title: Descriptive analysis of rabies in wild animals in the state of Sergipe, Brazil

description: ABSTRACT The wild cycle of rabies constitutes a serious challenge to epidemiological surveillance for disease control in domestic, companion or production animals, and in humans. The understanding of rabies virus circulation in the natural environment is increasingly important due to the constancy of natural reservoirs of the disease and the presence of potential vectors of the infection to humans and domestic animals. Aiming to evaluate the occurrence of rabies in the State of Sergipe a total of 935 hematophagous bats (Desmodus rotundus), 46 wild dogs (Cerdocyon thous) and 24 primates (Callithrix spp.) were analyzed from 1987 to 2014, of which 1 bat, 17 crab-eating foxes and no primates were positive. Due to the lack of positive results in hematophagous bats, the main vector of herbivorous rabies, more studies are needed to monitor cases, because from an epidemiological point of view, Sergipe is endemic for herbivorous rabies. Epidemiological surveillance of rabies virus in wild animals is primordial for the success of disease control programs in herds of domestic animals and humans.
DOI: 10.6084/m9.figshare.6207788.v1
title: Descriptive analysis of rabies in wild animals in the state of Sergipe, Brazil

description: ABSTRACT The wild cycle of rabies constitutes a serious challenge to epidemiological surveillance for disease control in domestic, companion or production animals, and in humans. The understanding of rabies virus circulation in the natural environment is increasingly important due to the constancy of natural reservoirs of the disease and the presence of potential vectors of the infection to humans and domestic animals. Aiming to evaluate the occurrence of rabies in the State of Sergipe a total of 935 hematophagous bats (Desmodus rotundus), 46 wild dogs (Cerdocyon thous) and 24 primates (Callithrix spp.) were analyzed from 1987 to 2014, of which 1 bat, 17 crab-eating foxes and no primates were positive. Due to the lack of positive results in hematophagous bats, the main vector of herbivorous rabies, more studies are needed to monitor cases, because from an epidemiological point of view, Sergipe is endemic for herbivorous rabies. Epidemiological surveillance of rabies virus in wild animals is primordial for the success of disease control programs in herds of domestic animals and humans.
DOI: 10.6084/m9.figshare.6207785
title: Development of a predicative model for identification of loss of stability and proteolysis occurrence in UHT milk

description: ABSTRACT The aim of this work was to develop a predictive model for identifying loss of stability and sedimentation in UHT milk by determining the enzymatic activity of aminopeptidasis in milk by spectrophotometry. Samples of raw milk, pasteurized and UHT after filling for 6 months in Southern Brazil were analyzed. Acidity, freezing point, fat, total solids, nonfat solids and density were analyzed in raw and pasteurized milk. Raw milk samples were also subjected to psychrotrophic count analysis and aminopeptidasis activity and UAT samples of stored milk were analyzed for degree of proteolysis through sensory analysis and aminopeptidasis activity. Sensory changes were observed in smaller storage time for samples of raw milk originated with psychrotrophic count above 107 CFU ml-1. There was no correlation between aminopeptidasis activity and proteolysis and there was also no significant correlation between physicochemical parameters and the occurrence of proteolysis in stored milk. The model was unable to predict loss of stability and occurrence of proteolysis in UHT milk.
DOI: 10.6084/m9.figshare.6207785.v1
title: Development of a predicative model for identification of loss of stability and proteolysis occurrence in UHT milk

description: ABSTRACT The aim of this work was to develop a predictive model for identifying loss of stability and sedimentation in UHT milk by determining the enzymatic activity of aminopeptidasis in milk by spectrophotometry. Samples of raw milk, pasteurized and UHT after filling for 6 months in Southern Brazil were analyzed. Acidity, freezing point, fat, total solids, nonfat solids and density were analyzed in raw and pasteurized milk. Raw milk samples were also subjected to psychrotrophic count analysis and aminopeptidasis activity and UAT samples of stored milk were analyzed for degree of proteolysis through sensory analysis and aminopeptidasis activity. Sensory changes were observed in smaller storage time for samples of raw milk originated with psychrotrophic count above 107 CFU ml-1. There was no correlation between aminopeptidasis activity and proteolysis and there was also no significant correlation between physicochemical parameters and the occurrence of proteolysis in stored milk. The model was unable to predict loss of stability and occurrence of proteolysis in UHT milk.
DOI: 10.6084/m9.figshare.6207779
title: URSOLIC ACID AND CIS-TILIROSIDE PRODUCED BY Merremia tomentosa AFFECT OVIPOSITION OF Leucoptera coffeella ON COFFEE PLANTS

description: To contribute to the development of new products to control the coffee leaf miner (Leucoptera coffeella), which is a major pest for coffee plants, this work aimed to select plant species able to produce substances active against this insect and to identify the active substances in the selected plant and their protein targets in the insect. Among the extracts of nineteen plant species, only that from leaves of Merremia tomentosa (Choisy) Hall. f. (Convolvulaceae) reduced the oviposition of L. coffeella on leaves of coffee plants. This extract was submitted to successive fractionation steps to achieve the isolation and identification of two active substances, ursolic acid (UA) and cis-tiliroside (CT). An in silico study showed that UA inhibits glycogen phosphorylases (GP) by binding to their allosteric site, while CT probably inhibits xanthine dehydrogenases (XT). As both GP and XT appear to be essential enzymes for insects, these results suggest that, during evolution, L. coffeella learned to identify plants producing inhibitors of these enzymes to avoid oviposition on such plants. Thus, both UA and CT have potential to be used as lead compounds in the development of new products for the control of the coffee leaf miner.
DOI: 10.6084/m9.figshare.6207779.v1
title: URSOLIC ACID AND CIS-TILIROSIDE PRODUCED BY Merremia tomentosa AFFECT OVIPOSITION OF Leucoptera coffeella ON COFFEE PLANTS

description: To contribute to the development of new products to control the coffee leaf miner (Leucoptera coffeella), which is a major pest for coffee plants, this work aimed to select plant species able to produce substances active against this insect and to identify the active substances in the selected plant and their protein targets in the insect. Among the extracts of nineteen plant species, only that from leaves of Merremia tomentosa (Choisy) Hall. f. (Convolvulaceae) reduced the oviposition of L. coffeella on leaves of coffee plants. This extract was submitted to successive fractionation steps to achieve the isolation and identification of two active substances, ursolic acid (UA) and cis-tiliroside (CT). An in silico study showed that UA inhibits glycogen phosphorylases (GP) by binding to their allosteric site, while CT probably inhibits xanthine dehydrogenases (XT). As both GP and XT appear to be essential enzymes for insects, these results suggest that, during evolution, L. coffeella learned to identify plants producing inhibitors of these enzymes to avoid oviposition on such plants. Thus, both UA and CT have potential to be used as lead compounds in the development of new products for the control of the coffee leaf miner.
DOI: 10.6084/m9.figshare.6207776
title: Biodiversity and family agriculture in Joanópolis, São Paulo State, Brazil: economic potential of the local flora

description: ABSTRACT The aim of this work was to study the economic potential of the local flora in order to point out or reinforce new productive chains based on biodiversity. The project was carried out with family farmers in the municipality of Joanópolis, in São Paulo State, Brazil. The work consisted of surveying the local flora by means of collections in all the properties benefited by the project and subsequent herborization. The visits were made annually, one in each season The species in the reproductive stage, with flowers and/or fruits, were collected for botanical identification. The collected species were evaluated in relation to their traditional use by the local population and the information obtained was systematized in a table as alternatives for agricultural production. As a result, we have listed more than a hundred possibilities from the local biodiversity for economic use and income generation.
DOI: 10.6084/m9.figshare.6207776.v1
title: Biodiversity and family agriculture in Joanópolis, São Paulo State, Brazil: economic potential of the local flora

description: ABSTRACT The aim of this work was to study the economic potential of the local flora in order to point out or reinforce new productive chains based on biodiversity. The project was carried out with family farmers in the municipality of Joanópolis, in São Paulo State, Brazil. The work consisted of surveying the local flora by means of collections in all the properties benefited by the project and subsequent herborization. The visits were made annually, one in each season The species in the reproductive stage, with flowers and/or fruits, were collected for botanical identification. The collected species were evaluated in relation to their traditional use by the local population and the information obtained was systematized in a table as alternatives for agricultural production. As a result, we have listed more than a hundred possibilities from the local biodiversity for economic use and income generation.
DOI: 10.6084/m9.figshare.6207770
title: An axisymmetric nodal averaged finite element

description: Abstract A nodal averaging technique which was earlier used for plane strain and three-dimensional problems is extended to include the axisymmetric one. Based on the virtual work principle, an expression for nodal force is found. In turn, a nodal force variation yields a stiffness matrix that proves to be non-symmetrical. But, cumbersome non-symmetrical terms can be rejected without the loss of Newton-Raphson iterations convergence. An approximate formula of volume for a ring of triangular profile is exploited in order to simplify program codes and also to accelerate calculations. The proposed finite element is intended primarily for quasistatic problems and large irreversible strain i.e. for metal forming analysis. As a test problem, deep rolling of a steel rod is studied.
DOI: 10.6084/m9.figshare.6207770.v1
title: An axisymmetric nodal averaged finite element

description: Abstract A nodal averaging technique which was earlier used for plane strain and three-dimensional problems is extended to include the axisymmetric one. Based on the virtual work principle, an expression for nodal force is found. In turn, a nodal force variation yields a stiffness matrix that proves to be non-symmetrical. But, cumbersome non-symmetrical terms can be rejected without the loss of Newton-Raphson iterations convergence. An approximate formula of volume for a ring of triangular profile is exploited in order to simplify program codes and also to accelerate calculations. The proposed finite element is intended primarily for quasistatic problems and large irreversible strain i.e. for metal forming analysis. As a test problem, deep rolling of a steel rod is studied.
DOI: 10.6084/m9.figshare.6207767
title: Palynology of native Amaranthaceae and Araliaceae in forest fragments of the Northwest of São Paulo State

description: ABSTRACT We investigated the pollen morphology of two native species of Amaranthaceae and three of Araliaceae from forest fragments in order to contribute with the palynology, taxonomy, and conservation of degraded areas. The pollen grains were acetolyzed, measured, qualitatively described and photographed using light and scanning electron microscopy. Quantitative data were analyzed by descriptive statistics. The pollen grains of Amaranthaceae are monads, small, apolar, spherical, pantoporate, and with metareticulate exine. For Araliaceae, the pollen grains are monads, small to medium, isopolar, subcircular to subtriangular, oblato-spheroidal to subprolate, 3-colporate, sometimes with vestibulum, lalongate endoaperture and microreticulate exine. The pollen data confirmed Amaranthaceae as a stenopalynous family. On the other hand, the species of Araliaceae studied characteristically present pollen grains apertures that can be used to differentiate them.