DOI: 10.5061/dryad.sr7c7
title: Data from: Inaccuracy of venous point-of-care glucose measurements in critically ill patients: a cross-sectional study

description: Introduction: Current guidelines and consensus recommend arterial and
 venous samples as equally acceptable for blood glucose assessment in
 point-of-care devices, but there is limited evidence to support this
 recommendation. We evaluated the accuracy of two devices for bedside
 point-of-care blood glucose measurements using arterial, fingerstick and
 catheter venous blood samples in ICU patients, and assessed which factors
 could impair their accuracy. Methods: 145 patients from a 41-bed adult
 mixed-ICU, in a tertiary care hospital were prospectively enrolled.
 Fingerstick, central venous (catheter) and arterial blood (indwelling
 catheter) samples were simultaneously collected, once per patient.
 Arterial measurements obtained with Precision PCx, and arterial,
 fingerstick and venous measurements obtained with Accu-chek Advantage II
 were compared to arterial central lab measurements. Agreement between
 point-of-care and laboratory measurements were evaluated with
 Bland-Altman, and multiple linear regression models were used to
 investigate interference of associated factors. Results: Mean difference
 between Accu-chek arterial samples versus central lab was 10.7 mg/dL (95%
 LA -21.3 to 42.7 mg/dL), and between Precision PCx versus central lab was
 18.6 mg/dL (95% LA -12.6 to 49.5 mg/dL). Accu-chek fingerstick versus
 central lab arterial samples presented a similar bias (10.0 mg/dL) but a
 wider 95% LA (-31.8 to 51.8 mg/dL). Agreement between venous samples with
 arterial central lab was the poorest (mean bias 15.1 mg/dL; 95% LA -51.7
 to 81.9). Hyperglycemia, low hematocrit, and acidosis were associated with
 larger differences between arterial and venous blood measurements with the
 two glucometers and central lab. Vasopressor administration was associated
 with increased error for fingerstick measurements. Conclusions: Sampling
 from central venous catheters should not be used for glycemic control in
 ICU patients. In addition, reliability of the two evaluated glucometers
 was insufficient. Error with Accu-chek Advantage II increases mostly with
 central venous samples. Hyperglycemia, lower hematocrit, acidosis, and
 vasopressor administration increase measurement error.
description: Data from: INACCURACY OF
 VENOUS POINT-OF-CARE GLUCOSE MEASUREMENTS IN CRITICALLY ILL PATIENTS: A
 CROSS-SECTIONAL STUDYData collected and
 presented here include arterial measurements obtained with Precision PCx
 (Abbott®, USA), arterial, fingerstick and venous measurements obtained
 with Accu-chek® Advantage II (Roche®, Switzerland) and arterial
 measurements obtained at the central lab (reference). Sequential Organ
 Failure Assessment score (SOFA score), Acute Physiology and Chronic Health
 Evaluation II (APACHE II score), mean arterial blood pressure, peripheral
 body temperature, hematocrit level, arterial pH, arterial oxygen
 saturation, room temperature and humidity, total bilirubin levels,
 triglycerides, use of vasopressors (norepinephrine and dopamine),
 acetaminophen, ascorbic acid, mannitol and mechanical ventilation are also
 provided.Data
 bank_19052015.xls