cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.17755823
title: DISTENDER Climate Simulations: Statistical Downscaling for Guimaraes_D3, Vertical level 2m, Global model EC-EARTH3, scenario Historical -  Guimaraes (Portugal)

description: Local (high resolution) climate data produced applying statistical downscaling techniques in the EU Project DISTENDER for five case studies. https://distender.eu/the-project . The datasets from the statistical downscaling come from the outputs of three global climate models that have been bias corrected (Parametric quantile mapping).
More details about the domains, the provided variable, levels and periods are provided in the README file.
DOI: 10.5281/zenodo.17755824
title: DISTENDER Climate Simulations: Statistical Downscaling for Guimaraes_D3, Vertical level 2m, Global model EC-EARTH3, scenario Historical -  Guimaraes (Portugal)

description: Local (high resolution) climate data produced applying statistical downscaling techniques in the EU Project DISTENDER for five case studies. https://distender.eu/the-project . The datasets from the statistical downscaling come from the outputs of three global climate models that have been bias corrected (Parametric quantile mapping).
More details about the domains, the provided variable, levels and periods are provided in the README file.
DOI: 10.17026/ar/ggfndw
title: PAN-00173467 - strap end group 10.1

description: &lt;p&gt;This find is registered at Portable Antiquities of the Netherlands with number PAN-00173467&lt;/p&gt;
description: Modified: 2025-04-29T14:47:12+02:00
DOI: 10.11582/2025.13eu1cfp
title: NorESM2-MM-CRiceS-historical

description: Historical simulation of NorESM2-MM with CRiceS modifications for air-sea gas exchanges.
DOI: 10.24342/35fe563a-8715-4590-961a-a7e219dde339
title: Clay database FI-CLAY/14/856

description: Partly multivariate database of geotechnical properties of Finnish clay soils. Database is available as supplementary material to an article (https://www.tandfonline.com/doi/full/10.1080/17499518.2020.1864410) and in 304dB database compilation by TC304 (http://140.112.12.21/issmge/tc304.htm)
DOI: 10.17026/ar/wruahs
title: PAN-00173083 - devotional pendant Modern period

description: &lt;p&gt;This find is registered at Portable Antiquities of the Netherlands with number PAN-00173083&lt;/p&gt;
description: Modified: 2025-04-26T11:47:21+02:00
DOI: 10.6084/m9.figshare.30751400
title: Sequences analysis of phyllosphere-associated bacterial isolates from celery and parsley and isolates from celery monocropping, parsley monocropping, celery-parsley intercropping and bulk soil.

description: <br>The dataset consists of the sequence analysis of phylosphere associated bacterial obtained from phyllosphere-associated bacterial isolates from celery and parsley and isolates from celery monocropping, parsley monocropping, celery-parsley intercropping and bulk soil. The dataset includes processed sequences, accession information, and metadata.
DOI: 10.6084/m9.figshare.30751400.v1
title: Sequences analysis of phyllosphere-associated bacterial isolates from celery and parsley and isolates from celery monocropping, parsley monocropping, celery-parsley intercropping and bulk soil.

description: <br>The dataset consists of the sequence analysis of phylosphere associated bacterial obtained from phyllosphere-associated bacterial isolates from celery and parsley and isolates from celery monocropping, parsley monocropping, celery-parsley intercropping and bulk soil. The dataset includes processed sequences, accession information, and metadata.
DOI: 10.17026/ar/jtyvag
title: PAN-00166147 - coin/coin-related, (anoniem, bisschoppelijk), “Friese” penning

description: &lt;p&gt;This find is registered at Portable Antiquities of the Netherlands with number PAN-00166147&lt;/p&gt;
description: Modified: 2025-04-28T13:25:03+02:00
DOI: 10.6084/m9.figshare.29447748
title: Bidirectional causal relationship between sleep disorders and thyroid function: a Mendelian randomization study

description: Sleep disorders and thyroid dysfunction are prevalent global health issues, significantly impairing physiological function and quality of life. Although studies suggest an association, the causal mechanisms remain unclear. This study employed bidirectional Mendelian randomization (MR) to investigate causality and identify key genes and pathways. Using large-scale European GWAS data, inverse-variance-weighted and sensitivity analyses assessed causal robustness, alongside functional enrichment and gene screening. Forward MR showed excessive daytime sleepiness and prolonged sleep duration negatively correlated with free triiodothyronine (FT3) and thyroxine (FT4), while insomnia negatively correlated with TSH. Reverse MR linked low FT3 and high TSH to increased sleep apnea risk, with high TSH potentially promoting morning preference. Functional enrichment implicated dopaminergic synapses, gap junctions, and unsaturated fatty acid biosynthesis. Key genes included GRM5, CRHR1, DRD2, SLC6A3, and GABRA2 (sleep-to-thyroid effects) and ITPK1, MBIP, PDE10A, PDE8B, and PRDM11 (thyroid-to-sleep effects). The study confirms bidirectional causality, with dopaminergic pathways potentially driving pathogenesis.
DOI: 10.6084/m9.figshare.29447748.v1
title: Bidirectional causal relationship between sleep disorders and thyroid function: a Mendelian randomization study

description: Sleep disorders and thyroid dysfunction are prevalent global health issues, significantly impairing physiological function and quality of life. Although studies suggest an association, the causal mechanisms remain unclear. This study employed bidirectional Mendelian randomization (MR) to investigate causality and identify key genes and pathways. Using large-scale European GWAS data, inverse-variance-weighted and sensitivity analyses assessed causal robustness, alongside functional enrichment and gene screening. Forward MR showed excessive daytime sleepiness and prolonged sleep duration negatively correlated with free triiodothyronine (FT3) and thyroxine (FT4), while insomnia negatively correlated with TSH. Reverse MR linked low FT3 and high TSH to increased sleep apnea risk, with high TSH potentially promoting morning preference. Functional enrichment implicated dopaminergic synapses, gap junctions, and unsaturated fatty acid biosynthesis. Key genes included GRM5, CRHR1, DRD2, SLC6A3, and GABRA2 (sleep-to-thyroid effects) and ITPK1, MBIP, PDE10A, PDE8B, and PRDM11 (thyroid-to-sleep effects). The study confirms bidirectional causality, with dopaminergic pathways potentially driving pathogenesis.
DOI: 10.6084/m9.figshare.29380355
title: Relationship between the geographical distribution of adolescent body size and photoperiod observed in Japan and China: a spatial analysis

description: Geographic analyses of Japanese children have shown a paradoxical trend: effective daylength – the duration of sunlight above a given illumination threshold – is negatively associated with height and positively with weight adjusted for height. These patterns suggest photoperiodic influences, possibly resembling thyroid hormone effects. To investigate whether similar associations exist in Han Chinese children, we analyzed province-level data from 2019 on average height and weight, using annual mean global solar radiation at each provincial capital as a proxy for effective daylength. We applied the regression model: Height = a₀ + a₁ × Weight − a₂ × Solar Radiation. Under normal physiological conditions, height and weight are typically proportional; thus, support for this model would imply solar radiation is linked to reduced height and increased weight. To assess regional variation, we used geographically weighted regression (GWR), which estimates location-specific coefficients. The results showed spatial heterogeneity: the weight coefficient was greater in western provinces, while the solar radiation coefficient tended to be smaller at higher latitudes. A global regression for provinces north of 30°N revealed statistically significant associations for 9-year-old boys. These findings suggest that the height – daylength and weight – daylength relationships observed in Japan may also exist in northern China, though weaker and more variable.
DOI: 10.6084/m9.figshare.29380355.v1
title: Relationship between the geographical distribution of adolescent body size and photoperiod observed in Japan and China: a spatial analysis

description: Geographic analyses of Japanese children have shown a paradoxical trend: effective daylength – the duration of sunlight above a given illumination threshold – is negatively associated with height and positively with weight adjusted for height. These patterns suggest photoperiodic influences, possibly resembling thyroid hormone effects. To investigate whether similar associations exist in Han Chinese children, we analyzed province-level data from 2019 on average height and weight, using annual mean global solar radiation at each provincial capital as a proxy for effective daylength. We applied the regression model: Height = a₀ + a₁ × Weight − a₂ × Solar Radiation. Under normal physiological conditions, height and weight are typically proportional; thus, support for this model would imply solar radiation is linked to reduced height and increased weight. To assess regional variation, we used geographically weighted regression (GWR), which estimates location-specific coefficients. The results showed spatial heterogeneity: the weight coefficient was greater in western provinces, while the solar radiation coefficient tended to be smaller at higher latitudes. A global regression for provinces north of 30°N revealed statistically significant associations for 9-year-old boys. These findings suggest that the height – daylength and weight – daylength relationships observed in Japan may also exist in northern China, though weaker and more variable.
DOI: 10.6084/m9.figshare.30352301
title: Medicinal chemistry perspective of ERK1/2 inhibitors in cancer treatment: an updated patent review (2019–present)

description: The mitogen-activated protein kinase (MAPK) pathway also known as the RAS/RAF/MEK/ERK pathway is a vital intracellular signaling cascade that regulates apoptosis, differentiation, proliferation, and signal transduction. This review focuses on the critical role of ERK1/2 in the MAPK pathway and its implication in various cancers. It presents a detailed analysis of ERK1/2 inhibitors currently undergoing clinical evaluation, along with recently patented ERK1/2 inhibitors. The data were compiled by systematically searching databases including SciFinder, PubMed, Scopus, Google Scholar, and Google Patents using the keyword ‘ERK’ for the period 2019 to the present. Since 2019, several heterocyclic ERK1/2 inhibitors have shown promise in overcoming resistance within the MAPK cascade. However, detailed investigations into mutant versus wild-type ERK1/2 binding dynamics remain sparse, and the development of non-traditional approaches like PROTAC-mediated ERK degradation is still in its nascent stage. To successfully transition ERK1/2 inhibitors from bench to bedside, several strategic directions must be prioritized. First, overcoming resistance remains a critical challenge. Future ERK inhibitors must effectively target downstream components. Second, there is a pressing need to move beyond traditional ATP-competitive inhibitors. In addition, the pharmacological properties of ERK-targeting agents to enhance clinical efficacy and safety.
DOI: 10.6084/m9.figshare.30352301.v1
title: Medicinal chemistry perspective of ERK1/2 inhibitors in cancer treatment: an updated patent review (2019–present)

description: The mitogen-activated protein kinase (MAPK) pathway also known as the RAS/RAF/MEK/ERK pathway is a vital intracellular signaling cascade that regulates apoptosis, differentiation, proliferation, and signal transduction. This review focuses on the critical role of ERK1/2 in the MAPK pathway and its implication in various cancers. It presents a detailed analysis of ERK1/2 inhibitors currently undergoing clinical evaluation, along with recently patented ERK1/2 inhibitors. The data were compiled by systematically searching databases including SciFinder, PubMed, Scopus, Google Scholar, and Google Patents using the keyword ‘ERK’ for the period 2019 to the present. Since 2019, several heterocyclic ERK1/2 inhibitors have shown promise in overcoming resistance within the MAPK cascade. However, detailed investigations into mutant versus wild-type ERK1/2 binding dynamics remain sparse, and the development of non-traditional approaches like PROTAC-mediated ERK degradation is still in its nascent stage. To successfully transition ERK1/2 inhibitors from bench to bedside, several strategic directions must be prioritized. First, overcoming resistance remains a critical challenge. Future ERK inhibitors must effectively target downstream components. Second, there is a pressing need to move beyond traditional ATP-competitive inhibitors. In addition, the pharmacological properties of ERK-targeting agents to enhance clinical efficacy and safety.
DOI: 10.6084/m9.figshare.30751509
title: Treatment of Lead-Contaminated Water Using Poly(2-Hydroxy 4-MethacryloyloxyBenzophenone): Adsorption Isotherms, Kinetics, and Thermodynamic Studies

description: Lead (Pb<sup>2+</sup>) is a pervasive, highly toxic pollutant that adversely affects human health and contaminates aquatic ecosystems through industrial discharges. This study evaluates the effectiveness of a novel material, poly(2-hydroxy4-methacryloyloxybenzophenone)(PHMB), for the removal of Pb<sup>+2</sup> from water. The monomer 2-hydroxy4-methacryloyloxybenzophenone (HMB) was synthesized and polymerized <i>via</i> free-radical polymerization to obtain the adsorbent PHMB. PHMB and HMB were characterized by spectroscopic techniques (FTIR,<sup>1</sup>H and <sup>13</sup>C NMR). Removal efficiency of Pb<sup>2+</sup> from water samples was examined using UV-Visible spectroscopy. Results showed that optimal Pb<sup>2+</sup> removal was achieved at pH 6 with a PHMB dosage of 0.75 g/L, and equilibrium was attained within 180 min. Isotherm analysis showed that the Freundlich model provided the best fit, indicating favorable multilayer adsorption of Pb<sup>2+</sup>, with a maximum adsorption capacity of 142.68 mg/g. The kinetic study revealed that the adsorption process was well-fitted by the pseudo-second-order kinetic model, indicating that chemisorption was the dominant adsorption mechanism. Additionally, thermodynamic data confirmed that the adsorption process was spontaneous and exothermic; the ΔG and ΔH values were −72 J/mol and −10kJ/mol, respectively. Furthermore, PHMB retained about 80% of its efficiency across multiple regeneration cycles; its reusability and high affinity for Pb<sup>2+</sup> make it a strong candidate for sustainable practical water purification.
DOI: 10.6084/m9.figshare.30751509.v1
title: Treatment of Lead-Contaminated Water Using Poly(2-Hydroxy 4-MethacryloyloxyBenzophenone): Adsorption Isotherms, Kinetics, and Thermodynamic Studies

description: Lead (Pb<sup>2+</sup>) is a pervasive, highly toxic pollutant that adversely affects human health and contaminates aquatic ecosystems through industrial discharges. This study evaluates the effectiveness of a novel material, poly(2-hydroxy4-methacryloyloxybenzophenone)(PHMB), for the removal of Pb<sup>+2</sup> from water. The monomer 2-hydroxy4-methacryloyloxybenzophenone (HMB) was synthesized and polymerized <i>via</i> free-radical polymerization to obtain the adsorbent PHMB. PHMB and HMB were characterized by spectroscopic techniques (FTIR,<sup>1</sup>H and <sup>13</sup>C NMR). Removal efficiency of Pb<sup>2+</sup> from water samples was examined using UV-Visible spectroscopy. Results showed that optimal Pb<sup>2+</sup> removal was achieved at pH 6 with a PHMB dosage of 0.75 g/L, and equilibrium was attained within 180 min. Isotherm analysis showed that the Freundlich model provided the best fit, indicating favorable multilayer adsorption of Pb<sup>2+</sup>, with a maximum adsorption capacity of 142.68 mg/g. The kinetic study revealed that the adsorption process was well-fitted by the pseudo-second-order kinetic model, indicating that chemisorption was the dominant adsorption mechanism. Additionally, thermodynamic data confirmed that the adsorption process was spontaneous and exothermic; the ΔG and ΔH values were −72 J/mol and −10kJ/mol, respectively. Furthermore, PHMB retained about 80% of its efficiency across multiple regeneration cycles; its reusability and high affinity for Pb<sup>2+</sup> make it a strong candidate for sustainable practical water purification.
DOI: 10.17026/ar/f7wo9s
title: PAN-00173084 - devotional pendant Modern period

description: &lt;p&gt;This find is registered at Portable Antiquities of the Netherlands with number PAN-00173084&lt;/p&gt;
description: Modified: 2025-04-26T11:46:30+02:00
DOI: 10.7910/dvn/exzwud
title: Replication Data for: Who is Trusted to Navigate the Storm? Gendered Leadership Preferences in Times of Crisis

description: This replication archive contains all scripts and data necessary to replicate the analysis in "Who is Trusted to Navigate the Storm? Gendered Leadership Preferences in Times of Crisis", published in Electoral Studies by Lotte Hargrave (University of Manchester), Jessica C. Smith (University of Southampton), Viktor Valgarðsson (University of Iceland), Daniel Devine (University of Southampton), Hannah Bunting (University of Exeter), and Caroline Leicht (University of Manchester).
DOI: 10.34740/kaggle/dsv/13937112
title: Annual Ground Water Quality Report -2025 (India)
DOI: 10.17026/ar/hcyuev
title: PAN-00157718 - Roman ceramic gaming piece

description: &lt;p&gt;This find is registered at Portable Antiquities of the Netherlands with number PAN-00157718&lt;/p&gt;
description: Modified: 2025-04-26T11:56:18+02:00
DOI: 10.17026/ar/5qssty
title: PAN-00084785 - Fede ring

description: &lt;p&gt;This find is registered at Portable Antiquities of the Netherlands with number PAN-00084785&lt;/p&gt;
description: Modified: 2025-04-30T16:09:23+02:00
DOI: 10.11588/duerer.online.692d7b2a60a77
title: Albrecht Dürers Haus, https://d-nb.info/gnd/1207558540
DOI: 10.5281/zenodo.17776007
title: Touche 2026 Causality Mock Dataset
DOI: 10.5281/zenodo.17776006
title: Touche 2026 Causality Mock Dataset
DOI: 10.5281/zenodo.17777089
title: Data extraction, transformation and loading in the farm register automation process, treatments and fertilization plan

description: The purpose of the research is represented by the automation of the process of drawing up the records of agricultural holdings through the necessary registers for the documentation and planning of plant protection works and the prevention of pollution with nitrates from agricultural sources. Through Robotic Process Automation (RPA) in agriculture, we can manage a wide range of repetitive or routine tasks. Using RPA to automate various agricultural operations allows companies and farmers to reduce unnecessary expenses while increasing production and profits. RPA is about simplifying complex agricultural processes that help save time and improve overall operational efficiency towards an important level of process planning and control that will enable farms to maximize their profitability with minimal losses. We carried out the Extraction Transformation and Loading (ETL) of the data related to the declared parcels from the files downloaded from the holdings' account, later by means of the algorithms the summation of the areas related to the crops and categories of use found in the single payment request was realized. The sheets containing the data related to the animals declared by the holding and the identification data of the holding were identified, and finally the sheets intended for storing the extracted data and the calculated values were created.
DOI: 10.5281/zenodo.17777088
title: Data extraction, transformation and loading in the farm register automation process, treatments and fertilization plan

description: The purpose of the research is represented by the automation of the process of drawing up the records of agricultural holdings through the necessary registers for the documentation and planning of plant protection works and the prevention of pollution with nitrates from agricultural sources. Through Robotic Process Automation (RPA) in agriculture, we can manage a wide range of repetitive or routine tasks. Using RPA to automate various agricultural operations allows companies and farmers to reduce unnecessary expenses while increasing production and profits. RPA is about simplifying complex agricultural processes that help save time and improve overall operational efficiency towards an important level of process planning and control that will enable farms to maximize their profitability with minimal losses. We carried out the Extraction Transformation and Loading (ETL) of the data related to the declared parcels from the files downloaded from the holdings' account, later by means of the algorithms the summation of the areas related to the crops and categories of use found in the single payment request was realized. The sheets containing the data related to the animals declared by the holding and the identification data of the holding were identified, and finally the sheets intended for storing the extracted data and the calculated values were created.
DOI: 10.17026/ar/iruguv
title: PAN-00122574 - finger ring with soldered square bezel

description: &lt;p&gt;This find is registered at Portable Antiquities of the Netherlands with number PAN-00122574&lt;/p&gt;
description: Modified: 2025-04-30T16:28:24+02:00
DOI: 10.5281/zenodo.17777161
title: Dataset: Biogas could enable the cost effective defossilization of n-propanol and its derivatives
DOI: 10.5281/zenodo.17777162
title: Dataset: Biogas could enable the cost effective defossilization of n-propanol and its derivatives
DOI: 10.7910/dvn/0w2bmf
title: Shanghai Health Education Tagging Corpus (Restricted Access)

description: This dataset contains a restricted corpus of Chinese health education resources curated by the Shanghai Municipal Center for Health Promotion (SMCHP) together with human- and model-generated multi-tier tags
DOI: 10.5517/ccdc.csd.cc26wsrn
title: CCDC 2052502: Experimental Crystal Structure Determination

description: Related Article: Wei-Feng Zheng|2023|CSD Communication|||
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.15468/dl.6xbmtn
title: Occurrence Download

description: A dataset containing 25 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is one of (Observation, Human Observation, Specimen)",
 "Country is one of (China, Pakistan)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Parnassius epaphus",
 "Year 2000-2025"
 ]
}

 The dataset includes 25 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0020249-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.dsg32e
title: Occurrence Download

description: A dataset containing 660 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Myotis daubentonii",
 "HasCoordinate is true",
 "Country is Netherlands",
 "Year is 2020,2022"
 ]
}

 The dataset includes 660 records from 3 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0020248-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.