cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.24785829.v1
title: Supplementary Material for: Preterm formula, fortified or unfortified human milk for very preterm infants, the PREMFOOD study, a parallel randomised feasibility trial

description: Objective: Uncertainty exists regarding optimal supplemental diet for very preterm infants if mother’s own milk (MM) is insufficient. We evaluated feasibility for a randomised controlled trial powered to detect important differences in health outcomes.
Methods: In this open, parallel, feasibility trial, we randomised infants 25+0-31+6 weeks gestation by opt-out consent, to one of three supplements to MM: unfortified human milk (UHM) (unfortified MM +/- unfortified pasteurised human donor milk (DM); fortified human milk (FHM) (fortified MM +/- fortified DM), and unfortified MM +/- preterm formula (PTF) from birth to 35+0 weeks post menstrual age. Feasibility outcomes included opt-outs, adherence rates, and slow growth safety criteria. We also obtained anthropometry, and magnetic resonance imaging body composition data at term and term plus 6 weeks (opt-in consent), as potential biomarkers for metabolic risk.
Results: 35 infants were randomised to UHM, 34 to FHM, and 34 to PTF groups, of which 21, 19, and 24 infants completed imaging at term. Opt-out consent was above target at 62%, while 6% of parents withdrew from feeding intervention. Two infants met predefined slow weight gain thresholds. There were no significant between-group differences in total adipose tissue volume at term (mean (sd): UHM: 0.870L (0.35L); FHM: 0.889L (0.31L); PTF: 0.809L (0.25L), p=0.66), nor in any other body composition measure or anthropometry at either timepoint.
Conclusions: Randomisation to UHM, FHM, and PTF feeding interventions by opt-out consent was acceptable to parents and clinical teams, associated with safe growth profiles, and body composition which did not indicate utility for biomarkers of metabolic risk.
DOI: 10.21227/ykpn-jx78
title: CICIDS2017 and UNBSW-NB15

description: The UNSW-NB15 Dataset is a compilation of raw network data packets crafted by the University of South Wales. This dataset is designed to create a blend of modern normal network activity and synthetic contemporary attack behavior. It encompasses nine types of attacks, including Fuzzers, Analysis, Backdoors, DoS, Exploits, Generic, Reconnaissance, Shellcode, and Worms, resulting in a total of 10 classes of traffic and 49 features.The CICIDS2017 dataset was curated by the Canadian Institute for Cybersecurity (CIC) using the B-Profile system, which simulates a network environment with a continuous variety of traffic attacks over a five-day period. This dataset serves as a popular training resource, containing both benign and up-to-date common attacks, resembling real-world data (PCAPs). It encompasses a total of 15 labels, including 14 network attacks and normal traffic, such as Botnet, Web Attack Brute Force, DoS, DDoS, Infiltration, Heartbleed, Bot, PortScan, and other common attacks based on the McAfee report of 2016.Furthermore, it includes 15 labels for traffic based on the results of network traffic analysis performed by CICFlowMeter. The analysis incorporates labeled flows derived from timestamps, source and destination IP addresses, source and destination ports, protocols, and attacks, all presented in CSV files
DOI: 10.6084/m9.figshare.24599037
title: Supplementary Material for: Human monocytes exposed to SARS-CoV-2 display features of innate immune memory producing high levels of CXCL10 upon restimulation

description: Introduction A role for innate immune memory in protection during COVID-19 infection or vaccination has been recently reported. However, no study so far has shown whether SARS-CoV-2 can train innate immune cells. The aim of this study was to investigate whether this virus can induce trained immunity in human monocytes. Methods Monocytes were exposed to inactivated (i)SARS-CoV-2 for 24 hours, followed by a resting period in medium only and a secondary stimulation on day 6 after which, the cytokine/chemokine and transcriptomic profiles were determined. Results Compared to untrained cells, the iSARS-CoV-2-trained monocytes secreted significantly higher levels of IL-6, TNF-α, CXCL10, CXCL9 and CXCL11 upon restimulation. Transcriptome analysis of iSARS-CoV-2 trained monocytes revealed increased expression of several inflammatory genes. As epigenetic and metabolic modifications are hallmarks of trained immunity, we analyzed the expression of genes related to these processes. Findings indicate that indeed SARS-CoV-2-trained monocytes show changes in the expression of genes involved in metabolic pathways including the tricarboxylic acid (TCA) cycle, amino acid metabolism and the expression of several epigenetic regulator genes. Using epigenetic inhibitors that block histone methyl and acetyl transferases, we observed that the capacity of monocytes to be trained by iSARS-CoV-2 was abolished. Conclusion Overall, our findings indicate that iSARS-CoV-2 can induce properties associated with trained immunity in human monocytes. These results contribute to the knowledge required for improving vaccination strategies to prevent infectious diseases.
DOI: 10.6084/m9.figshare.24534610
title: Supplementary Material for: Ayurveda for a type 1 diabetes patient with peripheral arterial occlusive disease (PAOD)

description: Introduction: The effect of Ayurvedic therapy in type 2 diabetes (t2d) is well documented. For people with type 1 diabetes (t1d), there is little evidence on the applicability of Ayurvedic therapy. This case illustrates the course of Ayurvedic treatment in a person with t1d accompanied by peripheral arterial occlusive disease (PAOD). Case presentation: The patient had insulin-dependent t1d since the age of 6 years. At 39 years of age, he developed progressive bilateral peripheral arterial occlusive disease (PAOD) of the femoral arteries. He presented claudication symptoms at a walking distance of 150m. 10 surgical interventions for recanalization have been performed. The PAOD put heavy psychological strains on the patient. He developed moderate depression with anxiety and complains of tinnitus and sleep disturbances. Through an initial outpatient Ayurvedic treatment focused on dietary and lifestyle changes, phytotherapeutics and a subsequent 6-week inpatient Ayurvedic treatment in India, a weight reduction of 12 kg, a reduction in insulin requirement to 65% of baseline, as well as a walking performance without restriction at medium load could be achieved. The depression and inner tension completely retreated, one-sided tinnitus, and existing sleep disturbances dissolved completely. The lasting effect was still perceptible 5 months after the inpatient stay. Conclusions: For this person with t1d with PAOD, outpatient and inpatient Ayurvedic therapy could generate a significant improvement of his situation. The case demonstrates that people with t1d can benefit from individualized Ayurvedic therapy. This case motivates to invest in Ayurvedic research for people with t1d and complications.
DOI: 10.6084/m9.figshare.24534610.v1
title: Supplementary Material for: Ayurveda for a type 1 diabetes patient with peripheral arterial occlusive disease (PAOD)

description: Introduction: The effect of Ayurvedic therapy in type 2 diabetes (t2d) is well documented. For people with type 1 diabetes (t1d), there is little evidence on the applicability of Ayurvedic therapy. This case illustrates the course of Ayurvedic treatment in a person with t1d accompanied by peripheral arterial occlusive disease (PAOD). Case presentation: The patient had insulin-dependent t1d since the age of 6 years. At 39 years of age, he developed progressive bilateral peripheral arterial occlusive disease (PAOD) of the femoral arteries. He presented claudication symptoms at a walking distance of 150m. 10 surgical interventions for recanalization have been performed. The PAOD put heavy psychological strains on the patient. He developed moderate depression with anxiety and complains of tinnitus and sleep disturbances. Through an initial outpatient Ayurvedic treatment focused on dietary and lifestyle changes, phytotherapeutics and a subsequent 6-week inpatient Ayurvedic treatment in India, a weight reduction of 12 kg, a reduction in insulin requirement to 65% of baseline, as well as a walking performance without restriction at medium load could be achieved. The depression and inner tension completely retreated, one-sided tinnitus, and existing sleep disturbances dissolved completely. The lasting effect was still perceptible 5 months after the inpatient stay. Conclusions: For this person with t1d with PAOD, outpatient and inpatient Ayurvedic therapy could generate a significant improvement of his situation. The case demonstrates that people with t1d can benefit from individualized Ayurvedic therapy. This case motivates to invest in Ayurvedic research for people with t1d and complications.
DOI: 10.6084/m9.figshare.24787482
title: Supplementary Material for: Cerebrospinal fluid concentration of the RET-inhibitor pralsetinib: a case report

description: Introduction
Pralsetinib is used to treat metastatic RET fusion-positive non-small cell lung cancer. Preclinical studies of pralsetinib have shown blood-brain barrier (BBB) penetration and intracranial activity. The intracranial efficacy of pralsetinib in patients with brain metastasis is considered to be greater compared to older multikinase tyrosine kinase inhibitors. However, CSF concentrations of pralsetinib in patients are not well described in literature. 

Case presentation
We report a case of a patient with RET fusion-positive NSCLC treated with pralsetinib. Despite of extracranial clinical and radiologic remission, the patient developed progressive brain metastasis during treatment with pralsetinib. We measured the pralsetinib concentration in plasma and in CSF to determine the CSF-to-unbound plasma ratio. The measured pralsetinib concentrations in plasma and CSF were 1951 ng/ml (~57 unbound) and 14 ng/mL, respectively, reflecting a CSF-to-unbound plasma concentration ratio of 0.25. Our findings were compared with data from literature.

Conclusion
We showed that pralsetinib penetrates the CSF well and is expected to be an effective treatment for brain metastasis of RET fusion-positive NSCLC. Lack of intracranial efficacy is more likely to be caused by intrinsic or acquired tumor resistance instead of suboptimal exposure of pralsetinib in the brain.
DOI: 10.6084/m9.figshare.24787482.v1
title: Supplementary Material for: Cerebrospinal fluid concentration of the RET-inhibitor pralsetinib: a case report

description: Introduction
Pralsetinib is used to treat metastatic RET fusion-positive non-small cell lung cancer. Preclinical studies of pralsetinib have shown blood-brain barrier (BBB) penetration and intracranial activity. The intracranial efficacy of pralsetinib in patients with brain metastasis is considered to be greater compared to older multikinase tyrosine kinase inhibitors. However, CSF concentrations of pralsetinib in patients are not well described in literature. 

Case presentation
We report a case of a patient with RET fusion-positive NSCLC treated with pralsetinib. Despite of extracranial clinical and radiologic remission, the patient developed progressive brain metastasis during treatment with pralsetinib. We measured the pralsetinib concentration in plasma and in CSF to determine the CSF-to-unbound plasma ratio. The measured pralsetinib concentrations in plasma and CSF were 1951 ng/ml (~57 unbound) and 14 ng/mL, respectively, reflecting a CSF-to-unbound plasma concentration ratio of 0.25. Our findings were compared with data from literature.

Conclusion
We showed that pralsetinib penetrates the CSF well and is expected to be an effective treatment for brain metastasis of RET fusion-positive NSCLC. Lack of intracranial efficacy is more likely to be caused by intrinsic or acquired tumor resistance instead of suboptimal exposure of pralsetinib in the brain.
DOI: 10.25318/9810014601-eng
title: Labour market characteristics of Canada's military and veteran populations: Canada, provinces and territories

description: Data on military service status by industry subsectors - North American Industry Classification System (NAICS) 2017, occupation - National Occupational Classification (NOC) 2021, work activity during the reference year, age and gender for the population aged 17 and over who worked since 2020, in private households, Canada, provinces and territories.
DOI: 10.34934/dvn/lxqrrx
title: Replication Data for Exploring Modern Bank Penetration: Evidence from the Early 20th-Century Netherlands

description: The files (R and CSV) contain the replication data for our analysis of a set of 2,355 death duty forms from the Netherlands in 1921, presented in our article “Exploring Modern Bank Penetration in the Netherlands in the 20th Century,” published in Economic History Review. A detailed description of this dataset is available in Ruben Peeters and Amaury de Vicq. “Inheritance Taxation Records in the Netherlands in 1921: The Memories Database” (forthcoming in 2023). The database itself is currently stored on the servers of University of Antwerp as part of the datafiles of the Social History of Finance Reserach Group. The paper also uses two other datasets, Tafel Vbis and the Dutch Banking Database (1880-1940). The Tafel Vbis dataset is described in a published paper by Ruben Peeters and Amaury de Vicq: de Vicq, A., & Peeters, R. (2020). “Introduction to the ‘Tafel v-bis’ Dataset: Death Duty Summary Information for The Netherlands, 1921,” Research Data Journal for the Humanities and Social Sciences, 5(1), 1-19. doi: https://doi.org/10.1163/24523666-bja10007. The Tafel Vbis datafiles are currently stored on the servers of University of Antwerp as part of the datafiles of the Social History of Finance Reserach Group, Odysseus Group. The Dutch Banking Database is described and published by DANS, and should be cited as follows: Vicq, A. de; Gelderblom, Prof. dr. O.; Jonker, Prof. dr. J. (2021): Dutch Banking Database, 1880-1940. DANS. https://doi.org/10.17026/dans-xre-kfdf
DOI: 10.6084/m9.figshare.24787107.v1
title: Supplementary Material for: Well-differentiated adenocarcinoma spreading widely in the gastric submucosa

description: A 56-year-old woman was referred to our hospital due to dry mouth. Diagnostic upper gastrointestinal endoscopy showed slightly elevated lesions both on the anterior wall and lesser curvature in the upper part of the stomach. Biopsy proven tuble-forming atypical cells in the two lesions led us to treat the presumed early gastric cancers with endoscopic submucosal dissection (ESD). Pathological examination of the ESD specimen showed well differentiated malignant cells spreading widely in the submucosa with positive lateral and deep margins. Retrospective image re-evaluation after ESD noticed us the correlation between the presumed early gastric cancers and the multiple submucosal cyst-like lesions in the gastric wall on computed tomography. Under the tentative diagnosis of gastric cancers originating not from orthotopic gastric mucosa but from submucosal ectopic gastric gland, the patient underwent laparoscopic total gastrectomy and regional lymph node dissection, revealing the tumor infiltration to the serosa and regional lymph node swelling. Post-operative pathological evaluation showed lymph node metastases, multiple submucosal cyst-like lesions lined with a single layer of presumably benign epithelium, papillary adenocarcinoma cells in the submucosa, and tubular adenocarcinoma cells both in the mucosal and subserosal regions. The patient was discharged on the postoperative 7th day without any events and completed adjuvant chemotherapy on an outpatient basis. General surgeons should note that cyst-like lesion(s) in the gastric wall might be a predictor of extensive submucosal cancer cell spreading even in a case of well differentiated gastric adenocarcinoma.
DOI: 10.6084/m9.figshare.24787107
title: Supplementary Material for: Well-differentiated adenocarcinoma spreading widely in the gastric submucosa

description: A 56-year-old woman was referred to our hospital due to dry mouth. Diagnostic upper gastrointestinal endoscopy showed slightly elevated lesions both on the anterior wall and lesser curvature in the upper part of the stomach. Biopsy proven tuble-forming atypical cells in the two lesions led us to treat the presumed early gastric cancers with endoscopic submucosal dissection (ESD). Pathological examination of the ESD specimen showed well differentiated malignant cells spreading widely in the submucosa with positive lateral and deep margins. Retrospective image re-evaluation after ESD noticed us the correlation between the presumed early gastric cancers and the multiple submucosal cyst-like lesions in the gastric wall on computed tomography. Under the tentative diagnosis of gastric cancers originating not from orthotopic gastric mucosa but from submucosal ectopic gastric gland, the patient underwent laparoscopic total gastrectomy and regional lymph node dissection, revealing the tumor infiltration to the serosa and regional lymph node swelling. Post-operative pathological evaluation showed lymph node metastases, multiple submucosal cyst-like lesions lined with a single layer of presumably benign epithelium, papillary adenocarcinoma cells in the submucosa, and tubular adenocarcinoma cells both in the mucosal and subserosal regions. The patient was discharged on the postoperative 7th day without any events and completed adjuvant chemotherapy on an outpatient basis. General surgeons should note that cyst-like lesion(s) in the gastric wall might be a predictor of extensive submucosal cancer cell spreading even in a case of well differentiated gastric adenocarcinoma.
DOI: 10.6084/m9.figshare.14618298
title: SL_SF_evolution

description: Data and R-script to reproduce results from manuscript
DOI: 10.25318/9810014601-fra
title: Caractéristiques sur le marché du travail de la population des militaires et des anciens combattants du Canada : Canada, provinces et territoires

description: Données sur l'état de service militaire selon les sous-secteurs d'industries - Système de classification des industries de l’Amérique du Nord (SCIAN) 2017, la profession – Classification nationale des professions (CNP) 2021, le travail pendant l'année de référence et l'âge et le genre pour la population âgée de 17 ans et plus qui travaillait depuis 2020, dans des ménages privés, au Canada, provinces et territoires.
DOI: 10.6084/m9.figshare.24799695
title: Annotation files for Longgeng 57

description: With LRS data, we assembled one genome and then generate a set of annotation data for an early-matured <i>Geng/japonica</i> glutinous rice mega variety genome, Longgeng 57 (LG57), which carries multiple elite traits including good grain quality and wide adaptability.
DOI: 10.5519/qd.a07xkr2h
title: Query on the Natural History Museum Data Portal (data.nhm.ac.uk) (8295 records)
DOI: 10.5519/qd.rn5gtqzk
title: Query on the Natural History Museum Data Portal (data.nhm.ac.uk) (8295 records)
DOI: 10.25318/9810014701-eng
title: Military family structure and household living arrangements: Canada, provinces and territories, census metropolitan areas and census agglomerations with parts

description: Data on military service status by census family status and household living arrangements, number of children, age of youngest child, age and gender for the population aged 17 years and over in census families in private households in Canada, provinces and territories, census metropolitan areas and census agglomerations with parts.
DOI: 10.15151/esrf-es-1430762064
title: strain imaging in Si membranes

description: strain imaging in Si membranes
DOI: 10.15151/esrf-es-1431196527
title: Scanning experiments on 3D printed polymer structures of RM82 liquid crystal elastomers

description: Scanning experiments on 3D printed polymer structures of RM82 liquid crystal elastomers
DOI: 10.15151/esrf-es-1430718182
title: DCT and S3DXRD on creep samples

description: DCT and S3DXRD on creep samples
DOI: 10.13140/rg.2.2.23981.67046
title: IMG-20211019-WA0329
DOI: 10.15151/esrf-es-1369836704
title: structural aspects of dynamic deformation of Zr-Cu-Al metallic glasses under laser shock loading

description: In the proposed experiment we will investigate the structural aspects of dynamic deformation of Zr-Cu-Al metallic glasses under laser shock loading. To this
end, a mid- power density laser with a nanoseconds pulse duration will be used to generate a shock wave and the local atomic arrangement of the glassy sample will be probed during its propagation by time-resolved X-ray absorption spectroscopy for Cu K-edge. By quantitative analysis of the EXAFS spectra we
will evaluate the parameters of local atomic environment of Cu atoms during shock compression. These results will help us to elucidate the structural origin of the experimentally observed anomalies in the pressure dependence of the sound/shock wave velocity in Zr-Cu-Al metallic glasses and identify a possible underlying pressure-induced structural transition in the amorphous phase.
DOI: 10.13140/rg.2.2.13915.34082
title: IMG-20211019-WA0329
DOI: 10.25318/9810014701-fra
title: Structure de la famille de militaires et situation des particuliers dans le ménage : Canada, provinces et territoires, régions métropolitaines de recensement et agglomérations de recensement y compris les parties

description: Données sur l'état de service militaire selon la situation dans la famille de recensement et la situation des particuliers dans le ménage, le nombre d'enfants, l'âge du plus jeune enfant, l'âge et le genre pour la population âgée de 17 ans et plus dans les familles de recensement dans les ménages privés au Canada, des provinces et territoires, des régions métropolitaines de recensement et des agglomérations de recensement et les parties.
DOI: 10.21985/n2-c7fh-j155
title: Knowledge graph descriptive statistics
DOI: 10.23728/b2share.86fca60588b14eaca5e2ce1e898e9955
title: Quest for Orthologs - 2022 Reference Proteomes participant dataset submitted by Domainoid+

description: Participant dataset OEBD00200002T7 submitted by Domainoid+ for event Quest for Orthologs - 2022 Reference Proteomes, organized by community QfO. Predictions made by Domainoid+ participant
DOI: 10.23728/b2share.8e7760f295cb40f7a1469baef66871c7
title: Quest for Orthologs - 2022 Reference Proteomes participant dataset submitted by InParanoid5

description: Participant dataset OEBD00200003BT submitted by InParanoid5 for event Quest for Orthologs - 2022 Reference Proteomes, organized by community QfO. Predictions made by InParanoid5 participant
DOI: 10.34740/kaggle/dsv/7193369
title: MoviesDatasets
DOI: 10.34740/kaggle/dsv/7193383
title: Mahanagar Yatayat Transport Dataset
DOI: 10.6084/m9.figshare.24799653
title: scRNA GPLVM data

description: Paper: https://arxiv.org/pdf/2209.06716.pdfCode repo: https://github.com/InfProbSciX/gplvm_scrna
DOI: 10.6084/m9.figshare.24799653.v1
title: scRNA GPLVM data

description: Paper: https://arxiv.org/pdf/2209.06716.pdfCode repo: https://github.com/InfProbSciX/gplvm_scrna
DOI: 10.5519/qd.2609xhag
title: Query on the Natural History Museum Data Portal (data.nhm.ac.uk) (1 records)
DOI: 10.6084/m9.figshare.24799800
title: 20231214_starrydata2

description: All data on Starrydata2, a database of experimental properties in the field of inorganic materials
DOI: 10.6084/m9.figshare.24799800.v1
title: 20231214_starrydata2

description: All data on Starrydata2, a database of experimental properties in the field of inorganic materials
DOI: 10.25387/g3.23283128
title: Supplemental Material for De-la-Cruz, Oyama, and Núñez-Farfán, 2023

description: 1) Chromosomes length from the genome of Datura stramonium
2) Annotation of the genome in gff3 format
3) Annotation of the genome in gft format
4) Genome assembly of Datura stramonium
5) Predicted proteins from the genome of Datura stramonium