cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.25934/pr00009410
title: Proprotein convertase subtilisin/kexin type 9 (PCSK9) Inhibitors on Cardiovascular and Heart Failure Outcomes

description: Background on Heart Failure
Heart failure is a condition where the heart is not able to effectively pump and circulate blood around the body. When the heart cannot pump enough blood, the body's cells may not receive enough oxygen and nutrients to function correctly, leading to tiredness, shortness of breath, and other health issues. Millions of people around the world live with heart failure, making it a significant public health concern. Finding effective treatments for heart failure can help improve daily life and longevity for these individuals.

Understanding PCSK9 Inhibitors and Bococizumab
PCSK9 inhibitors are a type of medicine that helps lower cholesterol levels in the blood by stopping a protein (called PCSK9) from working. When this protein is hindered, the liver is able to remove more cholesterol from the human body, which may help prevent heart problems like subsequent heart attacks. Bococizumab is a specific PCSK9 inhibitor that is used like this. Even though it is meant to reduce the risk of heart problems, researchers are not sure how well it works for those with heart failure.

Necessity of the Research
Our research is essential because it aims to fill in the gaps in our understanding of how well Bococizumab and similar drugs can help people with heart failure. By finding out if these medications reduce the risk of severe heart problems or the need to be hospitalized due to heart failure, our study could lead to better treatment strategies and outcomes for patients—potentially extending lives and improving their quality of life.

How the Research Will Be Conducted
To conduct this research, we will look back at data from past clinical trials, specifically the SPIRE 1 and 2 trials, where Bococizumab was studied in many patients. We will select information from these trials that concern patients with heart failure and analyze it to draw conclusions about the effectiveness and benefits of Bococizumab for those with this condition. This type of study design—a retrospective analysis of previous trials—is chosen because it allows us to utilize existing data to answer new questions without the time and cost of starting new trials.
DOI: 10.15468/dl.2qycd3
title: Occurrence Download

description: A dataset containing 292 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is one of (Russian Federation, Japan, China)",
 "TaxonKey is Eschrichtius robustus (Lilljeborg, 1861)"
 ]
}

 The dataset includes 292 records from 13 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0013404-241024112534372/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.3tv3cp
title: Occurrence Download

description: A dataset listing the 129 species recorded in GBIF matching the query:
{
 "DatasetKey" : [
 "is Spiders (Aracnida:Araneae) of PSU’s Botanical Garden (Perm, Russia)"
 ]
}

 The dataset's 129 records were derived from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0013394-241024112534372/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.6kp5hp
title: Occurrence Download

description: A dataset containing 36727 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON ((36.62635 -3.446147, 36.80726 -3.446147, 36.80726 -3.300472, 36.62635 -3.300472, 36.62635 -3.446147))",
 "Year is greater than or equal to 2013",
 "HasGeospatialIssue is false",
 "TaxonKey is Aves",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen, Specimen)"
 ]
 }
 }
 ]
}

 The dataset includes 36727 records from 7 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0013403-241024112534372/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.8whrdg
title: Occurrence Download

description: A dataset containing 16 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Specimen",
 "Country is Spain",
 "OccurrenceStatus is Present",
 "TaxonKey is Aurinia sinuata (L.) Griseb."
 ]
}

 The dataset includes 16 records from 9 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0013406-241024112534372/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15151/esrf-es-1893861834
title: Investigation of the stereochemical identity of lipid nanoparticles for RNA delivery

description: Lipid nanoparticles (LNPs) have proven to be a superior vehicle for the delivery of genetic material like RNA, also known as the basis for the COVID-19 vaccine. Much work has already been done on LNPs to understand their fundamentals and to identify optimal lipid compositions. Nevertheless, little is known about the influence of stereoisomers of single lipid components on transport efficiency and targeting properties of LNPs. We recently explored lipid stereoisomers, finding that isomeric differences can increase the transfection efficiency by several folds and also have an influence on cell selectivity. Recent reports show that the efficiency of endosomal escape can be attributed to the internal structure of LNPs. We postulated that the different isomers influence the lipid packing and thus the internal structure. In this proposal we plan to use SAXS to gain a deeper understanding of how lipid isomers change the nanostructure and thus the properties of the resulting LNP formulations.
DOI: 10.15151/esrf-es-1896679501
title: Structural investigation of membrane and water-soluble proteins

description: The portfolio of this BAG includes structural investigation of membrane proteins as well as soluble proteins relevant to various scientific fields. These range from basic science to application-related projects with impact on biotechnology (optogenetics, biocatalysts) and medicine (bacterial and viral pathogens, diseases involving protein aggregation).
DOI: 10.15151/esrf-es-1897081712
title: Macromolecular Crystallography in Lyon/Toulouse/Bordeaux / IBCP-MMSB ICBMS / IPBS LMGM / IECB IBGC CBMN

description: The different research teams who are part of this BAG are located in Lyon, Toulouse and Bordeaux. They are mainly working on worldwide health concerns
or biotechnological relevant projects. In more details, infectiology, molecular assemblies, biosynthetic pathways or glycobiology are their main research axises.
Important results have been obtained so far regarding the development of new therapeutic strategies against several infectious diseases or regarding plastic
bioremediation. In order to go further into details of all these studies, access to ESRF facilities is a requirement.
DOI: 10.15151/esrf-es-1883533213
title: Structural Determination of Novel Ytterbium Polyhydrides

description: Dense lanthanide polyhydrides are theorised to be promising candidates to exhibit high-temperature superconductivity, expedited by the observation of superconductivity in the La-H system. The heavy lanthanides have electronic properties which are thought to enhance superconductivity in hydrides, however, there remain systems that have yet to be fully explored, such as Yb-H. In our preliminary experiments on the Yb-H system, we observe the formation of two novel polyhydrides: Yb4H23 and YbH7.5, synthesised at pressures exceeding 150 GPa and temperatures above 1000 K. Here, we propose to comprehensively study the Yb-H system, establishing phase stability, determining the equations of state and exploring further hydrogenation. This is imperative to our parallel studies investigating their electronic transport properties.
DOI: 10.15151/esrf-es-1883535022
title: Determination of the local structure of boron carbide (B13C2) using the Pair Distribution Function method

description: The crystal structure of B13C2 remains consistent across different compositions, with the arrangement of boron and carbon atoms and the existence of vacancies contributing to its chemical disorder. The structural units consist of a 12-atom icosahedron connected to a 3-atom chain of C-B-C. Extensive efforts have been made to investigate how the atomic distributions of boron and carbon affect its properties, which are crucial for its technological applications (extraordinary hardness and high melting point). To investigate potential defects or local disorder, a PDF experiment is proposed. Based on the simulation for both an ideal unit cell and defective ones based on DFT method PDF can successfully reveal materials local structure. The synthesis of B13C2 has already been proven utilizing the SHS method.
DOI: 10.15151/esrf-es-1883559839
title: Unravelling the kinetics of active state formation of V,Fe-containing Co3-xMxO4 oxygen evolution electrocatalysts using time-resolved operan

description: The alkaline water splitting and oxygen evolution reaction (OER) using Co-based electrocatalysts is a promising approach to produce green H2 using electricity from renewable energies. Recent studies showed that the Co3O4 active state formation is linked to a reversible deactivation which opens up strategies to apply potentiodynamic reaction conditions rejuvenating the catalyst. But before a detailed operando understanding of the active state formation dynamics is required. In this experiment, we aim to clarify those for highly active V,Fe-containing Co3-xMxO4 electrocatalysts using operando time-resolved high-energy X-ray diffraction (HE-XRD) and link the structural findings to the catalytic deactivation under OER conditions. Thereby, we will reveal how the reversible (near-surface) restructuring as well as the potential-induced lattice strain is linked to the catalytic activity and will contribute to the understanding of decisive interfacial properties to improve electrocatalysts.
DOI: 10.15151/esrf-es-1947916305
title: Investigating the metamagnetic phase transition in FeRh.

description: FeRh undergoes an AFM-FM phase transition at about room temperature. Associated with a structural (lattice expansion) and resistivity changes amongst other key characteristic changes, this metamagnetic transition positions the material as a potential candidate for applications in memrsistive device development and ultimately neuromorphic computing. The objective of the experiment is to investigate with a nanometric resolution the effects of the transition on the structure of the sample and ultimately correlation with the magnetic properties of the material.
DOI: 10.15468/dl.ve5s4h
title: Occurrence Download

description: A dataset containing 33915 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Blysmus compressus (L.) Panz. ex Link"
 ]
}

 The dataset includes 33915 records from 407 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0013405-241024112534372/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.24768867
title: PilY1 regulates the dynamic architecture of the Type IV pilus machine in Pseudomonas aeruginosa

description: Figures for the paper
DOI: 10.6084/m9.figshare.24768867.v1
title: PilY1 regulates the dynamic architecture of the Type IV pilus machine in Pseudomonas aeruginosa

description: Figures for the paper
DOI: 10.6084/m9.figshare.25287526
title: An effector essential for virulence of necrotrophic fungi targets plant HIRs to inhibit host immunity

description: Source data of "An effector essential for virulence of necrotrophic fungi targets plant HIRs to inhibit host immunity"
DOI: 10.6084/m9.figshare.25287526.v1
title: An effector essential for virulence of necrotrophic fungi targets plant HIRs to inhibit host immunity

description: Source data of "An effector essential for virulence of necrotrophic fungi targets plant HIRs to inhibit host immunity"
DOI: 10.6084/m9.figshare.25835635
title: Inflammasome-targeted therapy might prevent adverse perinatal outcomes of recurrent chronic histiocytic intervillositis of unknown etiology

description: Comparison of IL-1b, IL-18, NLRP3, PYCARD, CASPASE 1, MEFV gene signatures expression in healthy controls, and CHI samples
DOI: 10.6084/m9.figshare.25835635.v1
title: Inflammasome-targeted therapy might prevent adverse perinatal outcomes of recurrent chronic histiocytic intervillositis of unknown etiology

description: Comparison of IL-1b, IL-18, NLRP3, PYCARD, CASPASE 1, MEFV gene signatures expression in healthy controls, and CHI samples
DOI: 10.15468/dl.y4qxsj
title: Occurrence Download

description: A dataset containing 628 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Blysmus sinocompressus Tang & F.T.Wang"
 ]
}

 The dataset includes 628 records from 20 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0013407-241024112534372/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.27232041
title: Wafer-scale vertical injection III-nitride deep-ultraviolet light emitters

description: Source data in the paper
DOI: 10.6084/m9.figshare.27232041.v1
title: Wafer-scale vertical injection III-nitride deep-ultraviolet light emitters

description: Source data in the paper
DOI: 10.15468/dl.jtheuj
title: Occurrence Download

description: A dataset containing 263 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON ((36.8106 7.627229, 36.87296 7.627229, 36.87296 7.700269, 36.8106 7.700269, 36.8106 7.627229))",
 "Year is greater than or equal to 2013",
 "HasGeospatialIssue is false",
 "TaxonKey is Aves",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen, Specimen)"
 ]
 }
 }
 ]
}

 The dataset includes 263 records from 3 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0013408-241024112534372/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.24771732.v1
title: Polyclonality overcomes fitness barriers in Apc-driven tumorigenesis

description: Source data accompanying main figures 1-4
DOI: 10.6084/m9.figshare.24771732
title: Polyclonality overcomes fitness barriers in Apc-driven tumorigenesis

description: Source data accompanying main figures 1-4
DOI: 10.6084/m9.figshare.27117423
title: Dynamic photomask directed lithography based on electrically stimulated nematic liquid crystal architectures

description: Source data are provided with this paper.
DOI: 10.6084/m9.figshare.27117423.v1
title: Dynamic photomask directed lithography based on electrically stimulated nematic liquid crystal architectures

description: Source data are provided with this paper.
DOI: 10.15468/dl.vc4vzr
title: Occurrence Download

description: A dataset containing 2632 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Cyperus amuricus Maxim."
 ]
}

 The dataset includes 2632 records from 130 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0013409-241024112534372/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.4jpz7f
title: Occurrence Download

description: A dataset containing 3999 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Bolboschoenus fluviatilis (Torr.) Soják"
 ]
}

 The dataset includes 3999 records from 215 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0013410-241024112534372/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.bfcbt7
title: Occurrence Download

description: A dataset containing 1469 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Bolboschoenus glaucus (Lam.) S.G.Sm."
 ]
}

 The dataset includes 1469 records from 141 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0013412-241024112534372/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.bqfz2u
title: Occurrence Download

description: A dataset containing 120 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is one of (Russian Federation, Japan, China)",
 "Geometry POLYGON((7 -2,168 -2,168 90,7 90,7 -2))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "TaxonKey is Eschrichtius robustus (Lilljeborg, 1861)"
 ]
}

 The dataset includes 120 records from 8 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0013414-241024112534372/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.m4kfsn
title: Occurrence Download

description: A dataset containing 187 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Bolboschoenus koshevnikovii (Litv.) A.E.Kozhevn."
 ]
}

 The dataset includes 187 records from 24 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0013415-241024112534372/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.usjngs
title: Occurrence Download

description: A dataset containing 29856 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is one of (Mexico, United States of America, Canada)",
 "Geometry POLYGON((-181 0,-90 0,-90 90,-181 90,-181 0))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "TaxonKey is Eschrichtius robustus (Lilljeborg, 1861)"
 ]
}

 The dataset includes 29856 records from 86 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0013413-241024112534372/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.qfs7ku
title: Occurrence Download

description: A dataset containing 99 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Cyperus alulatus J.Kern"
 ]
}

 The dataset includes 99 records from 13 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0013416-241024112534372/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.egrpzx
title: Occurrence Download

description: A dataset containing 6349 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Bolboschoenus laticarpus Marhold, Hroudová, Duchácek & Zákr."
 ]
}

 The dataset includes 6349 records from 113 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0013417-241024112534372/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.24tcaq
title: Occurrence Download

description: A dataset containing 2632 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Cyperus amuricus Maxim."
 ]
}

 The dataset includes 2632 records from 130 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0013418-241024112534372/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.27368385
title: <b>DATA SET </b>(Investigating the Efficacy of Fish-Assisted Activity on College Students’ Mental Health 2024)

description: This is a dataset acquired and analyzed during the study entitled "Investigating the Efficacy of Fish-Assisted Activity on College Students' Mental Health". It includes the total scores of participants on state anxiety, mindfulness, positive and negative affect schedule across three treatment conditions: visual, tactile, and a combination of both.
DOI: 10.15468/dl.2q7kzx
title: Occurrence Download

description: A dataset containing 250 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Cyperus arenarius Retz."
 ]
}

 The dataset includes 250 records from 42 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0013420-241024112534372/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.hm92eg
title: Occurrence Download

description: A dataset containing 1705 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is one of (Observation, Machine Observation, Human Observation, Occurrence evidence)",
 "Geometry POLYGON((105 0,131 0,131 42,105 42,105 0))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is one of (Carcinoscorpius rotundicauda (Latreille, 1802), Tachypleus tridentatus (Leach, 1819), Hippocampus Rafinesque, 1810, Trachidermus fasciatus Heckel, 1837)",
 "Year 1990-2024"
 ]
}

 The dataset includes 1705 records from 12 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0013421-241024112534372/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.t3prz8
title: Occurrence Download

description: A dataset containing 7532 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Cyperus articulatus L."
 ]
}

 The dataset includes 7532 records from 385 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0013422-241024112534372/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.uhusz3
title: Occurrence Download

description: A dataset containing 697096 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Quercus suber L."
 ]
}

 The dataset includes 697096 records from 442 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0056467-240229165702484/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.zf5adm
title: Occurrence Download

description: A dataset containing 51 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Boesenbergia pulchella (Ridl.) Merr."
 ]
}

 The dataset includes 51 records from 7 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0061649-240229165702484/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.4anb2h
title: Occurrence Download

description: A dataset containing 8617 species occurrences available in GBIF matching the query:
{
 "and" : [
 {
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen)"
 ]
 }
 }
 ]
 },
 "TaxonKey is Chrysococcyx xanthorhynchus (Horsfield, 1821)"
 ]
}

 The dataset includes 8617 records from 17 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0002572-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.