cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.11365163.v1
title: Genetic diversity and phylogenetic analysis of Chinese Han and Li ethnic populations from Hainan Island by 30 autosomal insertion/deletion polymorphisms

description: With the characteristics of low mutation rate, length variation and short amplicon size, insertion/deletion polymorphisms (InDels) have the advantages of both short tandem repeats (STRs) and single nucleotide polymorphisms (SNPs). Herein, people of two ethnicities from Hainan Island were genotyped for the first time using the Investigator DIPplex kit. We investigated the forensic parameters of the 30 InDels and the phylogenetic relationships among different populations. The accumulated powers of discrimination and powers of exclusion were 0.999 999 999 9646 and 0.9897 in the Hainan Han population and 0.999 999 999 9292 and 0.9861 in the Hainan Li population, respectively. Additionally, population comparisons among geographically, ethnically and linguistically diverse populations via cluster heatmap, multidimensional scaling, principal component analysis, phylogenetic tree and STRUCTURE analyses demonstrated that the Hainan Han population had genetic similarities to the other Han, She and Tujia populations, while the Hainan Li population had close genetic relationships to the Zhuang and Miao groups; both populations had a high degree of genetic differentiation from most Turkic-speaking populations. Aforementioned results suggested that the 30 autosomal InDels are highly polymorphic and informative, which are suitable for human identification and population genetics.
KEYPOINTSFour hundred and forty-five Chinese individuals from two ethnicities (Hainan Han and Hainan Li) were firstly analyzed by 30 autosomal InDels included in the Investigator DIPplex panel.Forensic parameters of the 30 InDels in the two populations showed high polymorphism and universality for human identification purposes.The Investigator DIPplex panel had a certain capacity of differentiating intercontinental populations and different language populations. Four hundred and forty-five Chinese individuals from two ethnicities (Hainan Han and Hainan Li) were firstly analyzed by 30 autosomal InDels included in the Investigator DIPplex panel. Forensic parameters of the 30 InDels in the two populations showed high polymorphism and universality for human identification purposes. The Investigator DIPplex panel had a certain capacity of differentiating intercontinental populations and different language populations.
DOI: 10.6084/m9.figshare.7170860
title: Additional file 6: of Rhomboid domain-containing protein 1 promotes breast cancer progression by regulating the p-Akt and CDK2 levels

description: Table S3. In MCF7 RHBDD1 knock-out cells, 8 upregulated genes that promoted the apoptotic process and 22 downregulated genes that inhibited the apoptotic process were listed. (XLS 31 kb)
DOI: 10.6084/m9.figshare.7170860.v1
title: Additional file 6: of Rhomboid domain-containing protein 1 promotes breast cancer progression by regulating the p-Akt and CDK2 levels

description: Table S3. In MCF7 RHBDD1 knock-out cells, 8 upregulated genes that promoted the apoptotic process and 22 downregulated genes that inhibited the apoptotic process were listed. (XLS 31 kb)
DOI: 10.6084/m9.figshare.19753786
title: Obesity patterns, metabolic abnormality, and diabetic kidney disease in patients with type 2 diabetes

description: The study aimed to examine the associations of obesity measures and metabolic abnormalities with DKD in a Chinese diabetic population
DOI: 10.6084/m9.figshare.7170875
title: Additional file 7: of Rhomboid domain-containing protein 1 promotes breast cancer progression by regulating the p-Akt and CDK2 levels

description: Table S4. 73 genes were differentially expressed between RHBDD1 knock-out and wild-type MCF7 cells. (XLS 16 kb)
DOI: 10.6084/m9.figshare.7170875.v1
title: Additional file 7: of Rhomboid domain-containing protein 1 promotes breast cancer progression by regulating the p-Akt and CDK2 levels

description: Table S4. 73 genes were differentially expressed between RHBDD1 knock-out and wild-type MCF7 cells. (XLS 16 kb)
DOI: 10.6084/m9.figshare.7170887
title: Additional file 8: of Rhomboid domain-containing protein 1 promotes breast cancer progression by regulating the p-Akt and CDK2 levels

description: Table S5. Patient characteristics in 84 breast cancer specimens. (XLS 8 kb)
DOI: 10.6084/m9.figshare.7170887.v1
title: Additional file 8: of Rhomboid domain-containing protein 1 promotes breast cancer progression by regulating the p-Akt and CDK2 levels

description: Table S5. Patient characteristics in 84 breast cancer specimens. (XLS 8 kb)
DOI: 10.6084/m9.figshare.19753833
title: N<sup>6</sup>-methyladenosine methyltransferase KIAA1429 elevates colorectal cancer aerobic glycolysis via HK2-dependent manner

description: Emerging evidence has emphasized the critical roles played by N<sup>6</sup>-methyladenosine RNA (m<sup>6</sup>A) modification in colorectal carcinoma (CRC) initiation and progression. However, the roles and mechanism of m<sup>6</sup>A and KIAA1429 in CRC progression require further clarification. Here, our research aimed to investigate the functions of KIAA1429 in CRC tumorigenesis. Results indicated that KIAA1429 up-regulation closely correlated to the poor prognosis of CRC patients. Bio-functional assays demonstrated that KIAA1429 promoted the aerobic glycolysis, including glucose uptake, lactate production, ATP generation and extracellular acidification rate (ECAR). Mechanistically, KIAA1429 positively up-regulated HK2 level via increasing its mRNA stability by binding the m<sup>6</sup>A site of HK2 mRNA via m<sup>6</sup>A-independent manner. Collectively, our work indicates that KIAA1429 has the potential to promote CRC carcinogenesis by targeting HK2 via m<sup>6</sup>A-independent manner, providing insight into the critical roles of m<sup>6</sup>A in CRC.
DOI: 10.6084/m9.figshare.19753833.v1
title: N<sup>6</sup>-methyladenosine methyltransferase KIAA1429 elevates colorectal cancer aerobic glycolysis via HK2-dependent manner

description: Emerging evidence has emphasized the critical roles played by N<sup>6</sup>-methyladenosine RNA (m<sup>6</sup>A) modification in colorectal carcinoma (CRC) initiation and progression. However, the roles and mechanism of m<sup>6</sup>A and KIAA1429 in CRC progression require further clarification. Here, our research aimed to investigate the functions of KIAA1429 in CRC tumorigenesis. Results indicated that KIAA1429 up-regulation closely correlated to the poor prognosis of CRC patients. Bio-functional assays demonstrated that KIAA1429 promoted the aerobic glycolysis, including glucose uptake, lactate production, ATP generation and extracellular acidification rate (ECAR). Mechanistically, KIAA1429 positively up-regulated HK2 level via increasing its mRNA stability by binding the m<sup>6</sup>A site of HK2 mRNA via m<sup>6</sup>A-independent manner. Collectively, our work indicates that KIAA1429 has the potential to promote CRC carcinogenesis by targeting HK2 via m<sup>6</sup>A-independent manner, providing insight into the critical roles of m<sup>6</sup>A in CRC.
DOI: 10.6084/m9.figshare.7170956
title: Additional file 2: of The frequency of ANCA-associated vasculitis in a national database of hospitalized patients in China

description: Pollutants in major cities. (XLSX 14 kb)
DOI: 10.6084/m9.figshare.7170956.v1
title: Additional file 2: of The frequency of ANCA-associated vasculitis in a national database of hospitalized patients in China

description: Pollutants in major cities. (XLSX 14 kb)
DOI: 10.6084/m9.figshare.7170962
title: Additional file 3: of The frequency of ANCA-associated vasculitis in a national database of hospitalized patients in China

description: Pollutants in provinces. (XLSX 17 kb)
DOI: 10.6084/m9.figshare.7170962.v1
title: Additional file 3: of The frequency of ANCA-associated vasculitis in a national database of hospitalized patients in China

description: Pollutants in provinces. (XLSX 17 kb)
DOI: 10.5281/zenodo.10672698
title: IODP Expedition 393 Ion chromatography

description: Cation and anion concentration in interstitial water samples was measured by ion chromatography using a conductivity detector. Cation analytes include calcium, magnesium, potassium, and sodium. Anion analytes include chloride, sulfate, and bromide.
DOI: 10.5281/zenodo.10672699
title: IODP Expedition 393 Ion chromatography

description: Cation and anion concentration in interstitial water samples was measured by ion chromatography using a conductivity detector. Cation analytes include calcium, magnesium, potassium, and sodium. Anion analytes include chloride, sulfate, and bromide.
DOI: 10.5281/zenodo.10672696
title: IODP Expedition 393 ICP-AES elemental analysis (solids)

description: Elemental contents in hard rock and sediment samples was measured by inductively coupled plasma - atomic emission spectrocopy (ICP-AES). Data are presented by element-wavelength pair (e.g., more than one calcium line may be reported). Elemental lines for which data do not exist for a particular expedition will not appear.
DOI: 10.5281/zenodo.10672697
title: IODP Expedition 393 ICP-AES elemental analysis (solids)

description: Elemental contents in hard rock and sediment samples was measured by inductively coupled plasma - atomic emission spectrocopy (ICP-AES). Data are presented by element-wavelength pair (e.g., more than one calcium line may be reported). Elemental lines for which data do not exist for a particular expedition will not appear.
DOI: 10.6084/m9.figshare.19753919
title: β-Patchoulene represses hypoxia-induced proliferation and epithelial-mesenchymal transition of liver cancer cells

description: Hepatocellular carcinoma (HCC) is a malignant tumor originating from liver epithelial cells with a high clinical mortality rate. β-Patchoulene (β-PAE) is a compound extracted from patchouli, which has analgesic, anti-inflammatory and antioxidant effects. This research aims to probe the impacts of β-PAE on hypoxia-induced HCC cell proliferation and epithelial-mesenchymal transition (EMT). Firstly, hypoxic injury models were constructed in HCC Huh-7 and MHCC97 cells, and the hypoxic injury cell models were then treated with different concentrations of β-PAE. The cell viability, proliferation, migration, invasion and apoptosis were checked by the cell counting kit-8 (CCK-8) assay, colony formation assay, Transwell assay, flow cytometry and terminal deoxyribonucleotide transferase (TdT)-mediated dUTP nick end labeling (TUNEL) assay. The expression of Survivin protein, EMT markers and the NF-κB/HIF-1α pathway was gauged by Western blot (WB) or cellular immunofluorescence or reverse transcription-polymerase chain reaction (RT-PCR). The <i>in-vivo</i> experiment was conducted to confirm the anti-tumor role of β-PAE. As a result, β-PAE abated hypoxia-induced HCC cell growth, proliferation, migration, invasion and EMT and facilitated apoptosis <i>in vitro</i> and <i>in vivo</i> dose-dependently. Further mechanism studies displayed that β-PAE inactivated the NF-κB/HIF-1α pathway, and HIF-1α activation significantly reversed the β-PAE-mediated tumor inhibition. β-PAE repressed the proliferation and EMT of hypoxia-induced HCC cells by choking the NF-κB/HIF-1α pathway, suggesting that β-PAE was a potential drug for HCC treatment.
DOI: 10.6084/m9.figshare.19753919.v1
title: β-Patchoulene represses hypoxia-induced proliferation and epithelial-mesenchymal transition of liver cancer cells

description: Hepatocellular carcinoma (HCC) is a malignant tumor originating from liver epithelial cells with a high clinical mortality rate. β-Patchoulene (β-PAE) is a compound extracted from patchouli, which has analgesic, anti-inflammatory and antioxidant effects. This research aims to probe the impacts of β-PAE on hypoxia-induced HCC cell proliferation and epithelial-mesenchymal transition (EMT). Firstly, hypoxic injury models were constructed in HCC Huh-7 and MHCC97 cells, and the hypoxic injury cell models were then treated with different concentrations of β-PAE. The cell viability, proliferation, migration, invasion and apoptosis were checked by the cell counting kit-8 (CCK-8) assay, colony formation assay, Transwell assay, flow cytometry and terminal deoxyribonucleotide transferase (TdT)-mediated dUTP nick end labeling (TUNEL) assay. The expression of Survivin protein, EMT markers and the NF-κB/HIF-1α pathway was gauged by Western blot (WB) or cellular immunofluorescence or reverse transcription-polymerase chain reaction (RT-PCR). The <i>in-vivo</i> experiment was conducted to confirm the anti-tumor role of β-PAE. As a result, β-PAE abated hypoxia-induced HCC cell growth, proliferation, migration, invasion and EMT and facilitated apoptosis <i>in vitro</i> and <i>in vivo</i> dose-dependently. Further mechanism studies displayed that β-PAE inactivated the NF-κB/HIF-1α pathway, and HIF-1α activation significantly reversed the β-PAE-mediated tumor inhibition. β-PAE repressed the proliferation and EMT of hypoxia-induced HCC cells by choking the NF-κB/HIF-1α pathway, suggesting that β-PAE was a potential drug for HCC treatment.
DOI: 10.6084/m9.figshare.24472485
title: Additional file 1 of Diminished ovarian reserve causes adverse ART outcomes attributed to effects on oxygen metabolism function in cumulus cells

description: Additional file 1: Supplementary Figure. A The gene relative expression in different groups by RNA-Seq. B The gene relative expression verified in different groups by RT-PCR. The file of DESCRIPTION contains a description of the names of the table data in the supplementary files.
DOI: 10.6084/m9.figshare.24472485.v1
title: Additional file 1 of Diminished ovarian reserve causes adverse ART outcomes attributed to effects on oxygen metabolism function in cumulus cells

description: Additional file 1: Supplementary Figure. A The gene relative expression in different groups by RNA-Seq. B The gene relative expression verified in different groups by RT-PCR. The file of DESCRIPTION contains a description of the names of the table data in the supplementary files.
DOI: 10.6084/m9.figshare.12413894
title: Additional file 1 of SCDb: an integrated database of stomach cancer

description: Additional file 1.
DOI: 10.6084/m9.figshare.12413894.v1
title: Additional file 1 of SCDb: an integrated database of stomach cancer

description: Additional file 1.
DOI: 10.6084/m9.figshare.12413897
title: Additional file 1 of Proteomic Analysis of Rice Subjected to Low Light Stress and Overexpression of OsGAPB Increases the Stress Tolerance

description: Additional file 1: Table S1. The related information of all the peptides identified in proteomic analysis.
DOI: 10.6084/m9.figshare.12413897.v1
title: Additional file 1 of Proteomic Analysis of Rice Subjected to Low Light Stress and Overexpression of OsGAPB Increases the Stress Tolerance

description: Additional file 1: Table S1. The related information of all the peptides identified in proteomic analysis.
DOI: 10.5281/zenodo.10672694
title: IODP Expedition 393 ICP-AES elemental analysis (interstitial water)

description: Elemental concentration in interstitial water samples was measured by inductively coupled plasma - atomic emission spectroscopy (ICP-AES). Data are presented by element-wavelength pair (e.g., more than one calcium line may be reported). Elemental lines for which data do not exist for a particular expedition will not appear.
DOI: 10.5281/zenodo.10672695
title: IODP Expedition 393 ICP-AES elemental analysis (interstitial water)

description: Elemental concentration in interstitial water samples was measured by inductively coupled plasma - atomic emission spectroscopy (ICP-AES). Data are presented by element-wavelength pair (e.g., more than one calcium line may be reported). Elemental lines for which data do not exist for a particular expedition will not appear.
DOI: 10.6084/m9.figshare.12413906
title: Additional file 2 of Proteomic Analysis of Rice Subjected to Low Light Stress and Overexpression of OsGAPB Increases the Stress Tolerance

description: Additional file 2: Table S2. Protein groups and majority proteins identified in proteomic analysis.
DOI: 10.6084/m9.figshare.12413906.v1
title: Additional file 2 of Proteomic Analysis of Rice Subjected to Low Light Stress and Overexpression of OsGAPB Increases the Stress Tolerance

description: Additional file 2: Table S2. Protein groups and majority proteins identified in proteomic analysis.
DOI: 10.6084/m9.figshare.12413909
title: Additional file 2 of Identification and characterization of male reproduction-related genes in pig (Sus scrofa) using transcriptome analysis

description: Additional file 2: Table S8. TSGs in pig.
DOI: 10.6084/m9.figshare.12413909.v1
title: Additional file 2 of Identification and characterization of male reproduction-related genes in pig (Sus scrofa) using transcriptome analysis

description: Additional file 2: Table S8. TSGs in pig.
DOI: 10.6084/m9.figshare.12413912
title: Additional file 3 of Proteomic Analysis of Rice Subjected to Low Light Stress and Overexpression of OsGAPB Increases the Stress Tolerance

description: Additional file 3: Table S3. Differentially expressed proteins between control light (0-NIP-CK) and low light (1-NIP-LL).
DOI: 10.6084/m9.figshare.11889624
title: Slab roll-back and crustal growth in the Eastern Junggar terrane, NW China: evidence from Carboniferous A-type granitoids and adakitic rocks

description: Revealing the formation mechanism of granitic plutons is vital for understanding crustal growth of Earth. Here, we present an integrated study of geochronological, elemental, whole rock Nd and zircon Hf isotopic data for a granitic pluton system that formed in the Eastern Junggar, NW China. Zircon U–Pb dating suggests the seven granitic plutons were emplaced at 356–312 Ma. The monzogranites have high alkaline and Zr contents, and high Ga/Al and TFe<sub>2</sub>O<sub>3</sub>/MgO ratios, which are geochemically similar to A-type granitoids. They display positive ɛ<sub>Nd</sub>(t) (+4.3 to +5.4) and ɛ<sub>Hf</sub>(t) (+7.6 to +12.4) values, and young Nd and Hf model ages, suggesting a lower arc crust source. The quartz monzodiorites have high Sr, low Y and Yb contents, yielding relatively high Sr/Y ratios that are similar to modern adakites. These rocks also have high positive ɛ<sub>Nd</sub>(t) (+7.6 to +8.0) and ɛ<sub>Hf</sub>(t) (+13.9 to +15.5) values, and young Nd and Hf model ages, indicating a subducted oceanic crustal source. In combination with data from other plutons in this area, we suggest that they were likely generated by roll-back of the subducted Junggar oceanic slab, which resulted in back-arc extension, asthenosphere upwelling, and partial melting of oceanic crust and lower arc crust.
DOI: 10.6084/m9.figshare.12413912.v1
title: Additional file 3 of Proteomic Analysis of Rice Subjected to Low Light Stress and Overexpression of OsGAPB Increases the Stress Tolerance

description: Additional file 3: Table S3. Differentially expressed proteins between control light (0-NIP-CK) and low light (1-NIP-LL).
DOI: 10.6084/m9.figshare.11889624.v1
title: Slab roll-back and crustal growth in the Eastern Junggar terrane, NW China: evidence from Carboniferous A-type granitoids and adakitic rocks

description: Revealing the formation mechanism of granitic plutons is vital for understanding crustal growth of Earth. Here, we present an integrated study of geochronological, elemental, whole rock Nd and zircon Hf isotopic data for a granitic pluton system that formed in the Eastern Junggar, NW China. Zircon U–Pb dating suggests the seven granitic plutons were emplaced at 356–312 Ma. The monzogranites have high alkaline and Zr contents, and high Ga/Al and TFe<sub>2</sub>O<sub>3</sub>/MgO ratios, which are geochemically similar to A-type granitoids. They display positive ɛ<sub>Nd</sub>(t) (+4.3 to +5.4) and ɛ<sub>Hf</sub>(t) (+7.6 to +12.4) values, and young Nd and Hf model ages, suggesting a lower arc crust source. The quartz monzodiorites have high Sr, low Y and Yb contents, yielding relatively high Sr/Y ratios that are similar to modern adakites. These rocks also have high positive ɛ<sub>Nd</sub>(t) (+7.6 to +8.0) and ɛ<sub>Hf</sub>(t) (+13.9 to +15.5) values, and young Nd and Hf model ages, indicating a subducted oceanic crustal source. In combination with data from other plutons in this area, we suggest that they were likely generated by roll-back of the subducted Junggar oceanic slab, which resulted in back-arc extension, asthenosphere upwelling, and partial melting of oceanic crust and lower arc crust.
DOI: 10.6084/m9.figshare.20278233
title: Critical analysis of Chagas disease treatment in different countries

description: As a result of globalization and constant migratory flows, Chagas disease is now present in almost all continents. The management and treatment of the disease is often influenced by the economic and social context of the societies that host patients. In this manuscript, we aim to provide a comparative review of approaches to patients with Chagas disease in the Americas and Europe.
DOI: 10.6084/m9.figshare.20278233.v1
title: Critical analysis of Chagas disease treatment in different countries

description: As a result of globalization and constant migratory flows, Chagas disease is now present in almost all continents. The management and treatment of the disease is often influenced by the economic and social context of the societies that host patients. In this manuscript, we aim to provide a comparative review of approaches to patients with Chagas disease in the Americas and Europe.
DOI: 10.6084/m9.figshare.12413921
title: Additional file 3 of Identification and characterization of male reproduction-related genes in pig (Sus scrofa) using transcriptome analysis

description: Additional file 3: Table S9. The significantly related TFs in porcine TSGs、NTSGs、LCTSGs、MCTSGs and HCTSGs.
DOI: 10.6073/pasta/adb5fccc494424032c1693b6eb82095a
title: Jornada Basin LTER: Wireless meteorological station at NPP P-SMAL site: 1-hour summary data: 2017 - ongoing

description: Hourly summary data at NPP P-SMAL met station. Average/maximum/minimum air temperature; average relative humidity and wind direction; average/maximum wind speed. These are measured and calculated based on 1-second scan rate of all sensors located at an automated meteorological station installed at Jornada LTER NPP P-SMAL site. Wind speed is measured at 75 cm, 150 cm, and 300 cm, wind direction at approximately 3m, and air temperature and relative humidity at approximate 2.5m. This climate station is operated by the Jornada LTER Program. This is an ONGOING dataset.
DOI: 10.6084/m9.figshare.12413921.v1
title: Additional file 3 of Identification and characterization of male reproduction-related genes in pig (Sus scrofa) using transcriptome analysis

description: Additional file 3: Table S9. The significantly related TFs in porcine TSGs、NTSGs、LCTSGs、MCTSGs and HCTSGs.
DOI: 10.6084/m9.figshare.19395741
title: Additional file 3 of Urinary metabolomics reveals the biological characteristics of early pregnancy in pigs

description: Additional file 3. Table S3. Metabolites identified at high confidence level.