cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.4733554
title: Left Ventricular Compressions Improve Hemodynamics in a Swine Model of Out-of-Hospital Cardiac Arrest

description: <b>Introduction</b>: We hypothesized that chest compressions located directly over the left ventricle (LV) would improve hemodynamics, including coronary perfusion pressure (CPP), and return of spontaneous circulation (ROSC) in a swine model of cardiac arrest. <b>Methods</b>: Transthoracic echocardiography (echo) was used to mark the location of the aortic root and the center of the left ventricle on animals (<i>n</i> = 26) which were randomized to receive chest compressions in one of the two locations. After a period of ten minutes of ventricular fibrillation, basic life support (BLS) with mechanical cardiopulmonary resuscitation (CPR) was initiated and performed for ten minutes followed by advanced cardiac life support (ACLS) for an additional ten minutes. During BLS the area of maximal compression was verified using transesophageal echo. CPP and other hemodynamic variables were averaged every two minutes. <b>Results</b>: Mean CPP was not significantly higher in the LV group during all time intervals of resuscitation; mean CPP was significantly higher in the LV group during the 12–14 minute interval of BLS and during minutes 22–30 of ACLS (p &lt; 0.05). Aortic systolic and diastolic pressures, right atrial systolic pressures, and end-tidal CO2 (ETCO2) were higher in the LV group during all time intervals of resuscitation (p &lt; 0.05). Nine of the left ventricle group (69%) achieved ROSC and survived to 60 minutes compared to zero of the aortic root group (p &lt; 0.001). <b>Conclusions</b>: In our swine model of cardiac arrest, chest compressions over the left ventricle improved hemodynamics and resulted in a greater proportion of animals with ROSC and survival to 60 minutes.
DOI: 10.6084/m9.figshare.4733581
title: Prevalence of inappropriate medication use in residential long-term care facilities for the elderly: A systematic review

description: <b>Background:</b> Multi-morbidity and polypharmacy of the elderly population enhances the probability of elderly in residential long-term care facilities experiencing inappropriate medication use. <b>Objectives:</b> The aim is to systematically review literature to assess the prevalence of inappropriate medication use in residential long-term care facilities for the elderly. <b>Methods:</b> Databases (MEDLINE, EMBASE) were searched for literature from 2004 to 2016 to identify studies examining inappropriate medication use in residential long-term care facilities for the elderly. Studies were eligible when relying on Beers criteria, STOPP, START, PRISCUS list, ACOVE, BEDNURS or MAI instruments. Inappropriate medication use was defined by the criteria of these seven instruments. <b>Results:</b> Twenty-one studies met inclusion criteria. Seventeen studies relied on a version of Beers criteria with prevalence ranging between 18.5% and 82.6% (median 46.5%) residents experiencing inappropriate medication use. A smaller range, from 21.3% to 63.0% (median 35.1%), was reported when considering solely the 10 studies that used Beers criteria updated in 2003. Prevalence varied from 23.7% to 79.8% (median 61.1%) in seven studies relying on STOPP. START and ACOVE were relied on in respectively four (prevalence: 30.5–74.0%) and two studies (prevalence: 28.9–58.0%); PRISCUS, BEDNURS and MAI were all used in one study each. <b>Conclusions:</b> Beers criteria of 2003 and STOPP were most frequently used to determine inappropriate medication use in residential long-term care facilities. Prevalence of inappropriate medication use strongly varied, despite similarities in research design and assessment with identical instrument(s).
DOI: 10.6084/m9.figshare.4733581.v1
title: Prevalence of inappropriate medication use in residential long-term care facilities for the elderly: A systematic review

description: <b>Background:</b> Multi-morbidity and polypharmacy of the elderly population enhances the probability of elderly in residential long-term care facilities experiencing inappropriate medication use. <b>Objectives:</b> The aim is to systematically review literature to assess the prevalence of inappropriate medication use in residential long-term care facilities for the elderly. <b>Methods:</b> Databases (MEDLINE, EMBASE) were searched for literature from 2004 to 2016 to identify studies examining inappropriate medication use in residential long-term care facilities for the elderly. Studies were eligible when relying on Beers criteria, STOPP, START, PRISCUS list, ACOVE, BEDNURS or MAI instruments. Inappropriate medication use was defined by the criteria of these seven instruments. <b>Results:</b> Twenty-one studies met inclusion criteria. Seventeen studies relied on a version of Beers criteria with prevalence ranging between 18.5% and 82.6% (median 46.5%) residents experiencing inappropriate medication use. A smaller range, from 21.3% to 63.0% (median 35.1%), was reported when considering solely the 10 studies that used Beers criteria updated in 2003. Prevalence varied from 23.7% to 79.8% (median 61.1%) in seven studies relying on STOPP. START and ACOVE were relied on in respectively four (prevalence: 30.5–74.0%) and two studies (prevalence: 28.9–58.0%); PRISCUS, BEDNURS and MAI were all used in one study each. <b>Conclusions:</b> Beers criteria of 2003 and STOPP were most frequently used to determine inappropriate medication use in residential long-term care facilities. Prevalence of inappropriate medication use strongly varied, despite similarities in research design and assessment with identical instrument(s).
DOI: 10.6084/m9.figshare.4733554.v1
title: Left Ventricular Compressions Improve Hemodynamics in a Swine Model of Out-of-Hospital Cardiac Arrest

description: <b>Introduction</b>: We hypothesized that chest compressions located directly over the left ventricle (LV) would improve hemodynamics, including coronary perfusion pressure (CPP), and return of spontaneous circulation (ROSC) in a swine model of cardiac arrest. <b>Methods</b>: Transthoracic echocardiography (echo) was used to mark the location of the aortic root and the center of the left ventricle on animals (<i>n</i> = 26) which were randomized to receive chest compressions in one of the two locations. After a period of ten minutes of ventricular fibrillation, basic life support (BLS) with mechanical cardiopulmonary resuscitation (CPR) was initiated and performed for ten minutes followed by advanced cardiac life support (ACLS) for an additional ten minutes. During BLS the area of maximal compression was verified using transesophageal echo. CPP and other hemodynamic variables were averaged every two minutes. <b>Results</b>: Mean CPP was not significantly higher in the LV group during all time intervals of resuscitation; mean CPP was significantly higher in the LV group during the 12–14 minute interval of BLS and during minutes 22–30 of ACLS (p &lt; 0.05). Aortic systolic and diastolic pressures, right atrial systolic pressures, and end-tidal CO2 (ETCO2) were higher in the LV group during all time intervals of resuscitation (p &lt; 0.05). Nine of the left ventricle group (69%) achieved ROSC and survived to 60 minutes compared to zero of the aortic root group (p &lt; 0.001). <b>Conclusions</b>: In our swine model of cardiac arrest, chest compressions over the left ventricle improved hemodynamics and resulted in a greater proportion of animals with ROSC and survival to 60 minutes.
DOI: 10.6084/m9.figshare.4733467
title: Datasets and code for the statistical analyses from Game-based situation awareness training for child and adult cyclists

description: Safe cycling requires situation awareness (SA), which is the basis for recognizing and anticipating hazards. Children have poorer SA than adults, which may put them at risk. This study investigates whether cyclists' SA can be trained with a video-based learning game. The effect of executive working memory on SA was also studied. Thirty-six children (9–10 years) and 22 adults (21–48 years) played the game. The game had 30 video clips filmed from a cyclist's perspective. Each clip was suddenly masked and two or three locations were presented. The player's task was to choose locations with a potential hazard and feedback was given for their answers. Working memory capacity (WMC) was tested with a counting span task. Children's and adults' performance improved while playing the game, which suggests that playing the game trains SA. Adults performed better than children, and they also glanced at hazards more while the video was playing. Children expectedly had a lower WMC than adults, but WMC did not predict performance within the groups. This indicates that SA does not depend on WMC when passively viewing videos.
DOI: 10.6084/m9.figshare.4733458
title: Tool-use frequency from Mitogenomes and relatedness do not predict frequency of tool-use by sea otters

description: Average frequency of tool use of individual sea otters. Animals used in this study are a subset of those presented here. The distribution of tool-use frequency was used to define frequent tool-users as individuals that used tools in at least 40% of observed prey captures.
DOI: 10.6084/m9.figshare.4733458.v1
title: Tool-use frequency from Mitogenomes and relatedness do not predict frequency of tool-use by sea otters

description: Average frequency of tool use of individual sea otters. Animals used in this study are a subset of those presented here. The distribution of tool-use frequency was used to define frequent tool-users as individuals that used tools in at least 40% of observed prey captures.
DOI: 10.6084/m9.figshare.4733467.v2
title: Datasets and code for the statistical analyses from Game-based situation awareness training for child and adult cyclists

description: Safe cycling requires situation awareness (SA), which is the basis for recognizing and anticipating hazards. Children have poorer SA than adults, which may put them at risk. This study investigates whether cyclists' SA can be trained with a video-based learning game. The effect of executive working memory on SA was also studied. Thirty-six children (9–10 years) and 22 adults (21–48 years) played the game. The game had 30 video clips filmed from a cyclist's perspective. Each clip was suddenly masked and two or three locations were presented. The player's task was to choose locations with a potential hazard and feedback was given for their answers. Working memory capacity (WMC) was tested with a counting span task. Children's and adults' performance improved while playing the game, which suggests that playing the game trains SA. Adults performed better than children, and they also glanced at hazards more while the video was playing. Children expectedly had a lower WMC than adults, but WMC did not predict performance within the groups. This indicates that SA does not depend on WMC when passively viewing videos.
DOI: 10.6084/m9.figshare.4733467.v1
title: Datasets and code for the statistical analyses from Game-based situation awareness training for child and adult cyclists

description: Safe cycling requires situation awareness (SA), which is the basis for recognizing and anticipating hazards. Children have poorer SA than adults, which may put them at risk. This study investigates whether cyclists' SA can be trained with a video-based learning game. The effect of executive working memory on SA was also studied. Thirty-six children (9–10 years) and 22 adults (21–48 years) played the game. The game had 30 video clips filmed from a cyclist's perspective. Each clip was suddenly masked and two or three locations were presented. The player's task was to choose locations with a potential hazard and feedback was given for their answers. Working memory capacity (WMC) was tested with a counting span task. Children's and adults' performance improved while playing the game, which suggests that playing the game trains SA. Adults performed better than children, and they also glanced at hazards more while the video was playing. Children expectedly had a lower WMC than adults, but WMC did not predict performance within the groups. This indicates that SA does not depend on WMC when passively viewing videos.
DOI: 10.6084/m9.figshare.4733320
title: EDS raw data

description: Raw data of weight percentages for trace element and metals measured in sections of P. ichthyoxanthon.
DOI: 10.6084/m9.figshare.4733254
title: Supplementary Material for: Sex-Specific Transcript Diversity in the Fly Head Is Established during Pupal Stages and Adulthood and Is Largely Independent of the Mating Process and the Germline

description: Alternative splicing (AS), the process which generates multiple RNA and protein isoforms from a single pre-mRNA, greatly contributes to transcript diversity and compensates for the fact that the gene number does not scale with organismal complexity. A number of genomic approaches have established that the extent of AS is much higher than previously expected, raising questions on its spatio-temporal regulation and function. In the present study, we address AS in the context of sex-specific neuronal development in the model <i>Drosophila melanogaster</i>. We report that at least 47 genes display sex-specific AS in the adult fly head. Unlike targets of the classical <i>Sex lethal</i>-dependent sex determination cascade, sex-specific isoforms of the vast majority of these genes are not present during larval development but start accumulating during metamorphosis or later, indicating the existence of novel mechanisms in the induction of sex-specific AS. We also established that sex-specific AS in the adult fly head is largely independent of the germline or the mating process. Finally, we investigated the role of sex-specific AS of the sulfotransferase <i>Tango13</i> pre-mRNA and provide first evidence that differential expression of certain isoforms of this protein significantly affects courtship and mating behavior in male flies.
DOI: 10.6084/m9.figshare.4733245
title: Supplementary Material for: A High Ki67/BCL2 Index Could Predict Lower Disease-Free and Overall Survival in Intestinal-Type Gastric Cancer

description: <b><i>Background:</i></b> The heterogeneity of gastric cancer makes the identification of potential prognostic indicators particularly important. The Ki67 and BCL2 proteins are known prognostic markers for different types of cancer. Ki67 is associated with cell proliferation, whereas BCL2 has antiproliferative roles. A combined marker based on these opposite functions might provide improved prognostic information in gastric cancer. <b><i>Method:</i></b> Ki67 and BCL2 expression was assessed in 276 gastric adenocarcinoma tissue microarrays. A Ki67/BCL2 index based on the relative expression of each protein was divided into low- and high-risk groups using receiver operating characteristic curves. <b><i>Results:</i></b> A high Ki67/BCL2 index significantly correlated with advanced stage, recurrence, intestinal type, high histologic grade, and lymphatic and perineural invasion (all p &lt; 0.05). Univariate and multivariate analyses revealed a significant relationship between disease-free or overall survival and the Ki67/BCL2 index in intestinal-type gastric cancer (all p &lt; 0.05). <b><i>Conclusions:</i></b> A combined marker using Ki67 and BCL2 could be a useful indicator for predicting survival in patients with intestinal-type gastric cancer.
DOI: 10.6084/m9.figshare.4733254.v1
title: Supplementary Material for: Sex-Specific Transcript Diversity in the Fly Head Is Established during Pupal Stages and Adulthood and Is Largely Independent of the Mating Process and the Germline

description: Alternative splicing (AS), the process which generates multiple RNA and protein isoforms from a single pre-mRNA, greatly contributes to transcript diversity and compensates for the fact that the gene number does not scale with organismal complexity. A number of genomic approaches have established that the extent of AS is much higher than previously expected, raising questions on its spatio-temporal regulation and function. In the present study, we address AS in the context of sex-specific neuronal development in the model <i>Drosophila melanogaster</i>. We report that at least 47 genes display sex-specific AS in the adult fly head. Unlike targets of the classical <i>Sex lethal</i>-dependent sex determination cascade, sex-specific isoforms of the vast majority of these genes are not present during larval development but start accumulating during metamorphosis or later, indicating the existence of novel mechanisms in the induction of sex-specific AS. We also established that sex-specific AS in the adult fly head is largely independent of the germline or the mating process. Finally, we investigated the role of sex-specific AS of the sulfotransferase <i>Tango13</i> pre-mRNA and provide first evidence that differential expression of certain isoforms of this protein significantly affects courtship and mating behavior in male flies.
DOI: 10.6084/m9.figshare.4733245.v1
title: Supplementary Material for: A High Ki67/BCL2 Index Could Predict Lower Disease-Free and Overall Survival in Intestinal-Type Gastric Cancer

description: <b><i>Background:</i></b> The heterogeneity of gastric cancer makes the identification of potential prognostic indicators particularly important. The Ki67 and BCL2 proteins are known prognostic markers for different types of cancer. Ki67 is associated with cell proliferation, whereas BCL2 has antiproliferative roles. A combined marker based on these opposite functions might provide improved prognostic information in gastric cancer. <b><i>Method:</i></b> Ki67 and BCL2 expression was assessed in 276 gastric adenocarcinoma tissue microarrays. A Ki67/BCL2 index based on the relative expression of each protein was divided into low- and high-risk groups using receiver operating characteristic curves. <b><i>Results:</i></b> A high Ki67/BCL2 index significantly correlated with advanced stage, recurrence, intestinal type, high histologic grade, and lymphatic and perineural invasion (all p &lt; 0.05). Univariate and multivariate analyses revealed a significant relationship between disease-free or overall survival and the Ki67/BCL2 index in intestinal-type gastric cancer (all p &lt; 0.05). <b><i>Conclusions:</i></b> A combined marker using Ki67 and BCL2 could be a useful indicator for predicting survival in patients with intestinal-type gastric cancer.
DOI: 10.6084/m9.figshare.4733188
title: Geology of the Shakespeare quadrangle (H03), Mercury

description: By using images acquired by the Mercury dual imaging system (MDIS) on-board the MESSENGER spacecraft during 2008–2015 and available DTMs, a new 1:3,000,000-scale geological map of the Shakespeare quadrangle of Mercury has been compiled. The quadrangle is located between latitudes 22.5°–65.0°N and longitudes 270.0°–180.0°E and covers an area of about 5 million km<sup>2</sup>. The mapping was based on photo-interpretation performed on a reference monochromatic basemap of reflectance at 166 m/pixel resolution. The geological features were digitized within a geographic information system with a variable mapping scale between 1:300,000 and 1:600,000. This quadrangle is characterized by the occurrence of three main types of plains materials and four basin materials (pertaining to the Caloris basin), whose geologic boundaries have been here redefined compared to the previous map of the quadrangle. The stratigraphic relationships between the craters were based on three main degradation morphologies. Furthermore, previously unmapped tectonic landforms were detected and interpreted as thrusts or wrinkle ridges.
DOI: 10.6084/m9.figshare.4733188.v1
title: Geology of the Shakespeare quadrangle (H03), Mercury

description: By using images acquired by the Mercury dual imaging system (MDIS) on-board the MESSENGER spacecraft during 2008–2015 and available DTMs, a new 1:3,000,000-scale geological map of the Shakespeare quadrangle of Mercury has been compiled. The quadrangle is located between latitudes 22.5°–65.0°N and longitudes 270.0°–180.0°E and covers an area of about 5 million km<sup>2</sup>. The mapping was based on photo-interpretation performed on a reference monochromatic basemap of reflectance at 166 m/pixel resolution. The geological features were digitized within a geographic information system with a variable mapping scale between 1:300,000 and 1:600,000. This quadrangle is characterized by the occurrence of three main types of plains materials and four basin materials (pertaining to the Caloris basin), whose geologic boundaries have been here redefined compared to the previous map of the quadrangle. The stratigraphic relationships between the craters were based on three main degradation morphologies. Furthermore, previously unmapped tectonic landforms were detected and interpreted as thrusts or wrinkle ridges.
DOI: 10.6084/m9.figshare.4733089
title: raw data for PeerJ(2017.Mar)

description: NGS raw data for PeerJ titled " <strong>Development of phytoplankton-specific 23S universal primer set for Illumina MiSeq sequencing platform</strong><strong>"</strong><strong> </strong><strong> </strong>
DOI: 10.6084/m9.figshare.4733089.v1
title: raw data for PeerJ(2017.Mar)

description: NGS raw data for PeerJ titled " <strong>Development of phytoplankton-specific 23S universal primer set for Illumina MiSeq sequencing platform</strong><strong>"</strong><strong> </strong><strong> </strong>
DOI: 10.6084/m9.figshare.4733059
title: The role of forest resources in income inequality in Cameroon

description: The present study focuses on forest incomes of households around forest concessions in Cameroon. The contributions of forest income to the economy and well-being of households were measured and the explanatory factors for heterogeneity determined. We used the Gini index to evaluate the distribution of household forest incomes and their influence on well-being and income inequality amongst forest-dependent households. Three TOBIT econometric models with sample selection were estimated to identify factors that influence the level of each source of forest income. Results from our analysis show that forest contributes on average 38% of total annual household income with 19, 13 and 6% from illegal logging, hunting and non-timber forest products (NTFPs) of vegetal origin, respectively. Forest income overall contributes in increasing disparities among people by 3%. Income from illegal logging was found to be a major source of income inequality while other forest income sources such as NTFPs and hunting slightly reduced income inequality. Access to villages and the amount of agricultural income were the main factors that explained the differences in forest income.
DOI: 10.7795/720.20180517
title: Datasets for Multidimensional model to correct PV device performance measurements taken under diffuse irradiation to reference conditions

description: The datasets provided here contain spectral- and angular-dependent responsivities of three different reference solar cells measured in Plag , et al., 2017, Angular dependent spectral responsivity — Traceable measurements on optical losses in PV devices. Prog Photovolt Res Appl.;1–14. and used in Plag, et al., 2018, Multidimensional model to correct PV device performance measurements taken under diffuse irradiation to reference conditions. The additionally provided uvspec input file allow radiative transfer simulations that are similar to those conducted in Plag, et al., 2018. The spectral radiance field calculated with libRadtran can be used to study spectral-angular mismatch effects and optical losses under diffuse solar irradiation. Funding: The research work leading to this article was carried out within the scope of the EMRP ENG55 project “Towards an energy-based parameter for photovoltaic classification” (PhotoClass). The EMRP is jointly funded by the EMRP participating countries within EURAMET and the European Union.
DOI: 10.6084/m9.figshare.4733056
title: cafe joris le retour

description: les données de joris sur l'influence de la chémocyanine sur le métabolisme de Frankianstein.<br>