cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.10725805
title: [IO Islamic 1159] يوسف و زليخا

description: Yûsuf-u-Zalîkhâ

This manuscript is now IO Islamic 1594 in the India Office collections.

[metadata: Hermann Ethé, Catalogue of Persian Manuscripts in the Library of the India Office, 2 vols. (Oxford: India Office, 1903): volume 1, number 1159 here with notations and hyperlinks].


1594

Another copy of the same.

Beginning as in the preceding copy.

No date. Ff. 193a-195b are left blank.

No. 1159, margin-column, ff. 179b-348, ll. 28-40; (14-20 baits), written by different hands in irregular Nasta’lîḳ, which sometimes resembles Shikasta.
DOI: 10.15468/gfa2j5
title: 2023_deoksan_bird_observation_information_nsmk_731

description: 2023 Deoksan Provincial Park Investigation
Subject to investigation: Bird
DOI: 10.6084/m9.figshare.13049182.v1
title: Additional file 1 of Baseline sensitivity and resistance risk assessment of Valsa mali to pyraclostrobin

description: Additional file 1: Table S1. Sensitivity assay of Valsa mali to pyraclostrobin in AEA medium with or without SHAM.
DOI: 10.6084/m9.figshare.13049182
title: Additional file 1 of Baseline sensitivity and resistance risk assessment of Valsa mali to pyraclostrobin

description: Additional file 1: Table S1. Sensitivity assay of Valsa mali to pyraclostrobin in AEA medium with or without SHAM.
DOI: 10.22000/1911
title: Dataset belonging to publication: "Microgels react to incorporation of solutes: Superchaotropic Nano-ions"

description: Data to the figures in the publication, raw data to zetasizer, multi-angle DLS, SLS, SAXS and Raman
DOI: 10.5281/zenodo.10725800
title: Datasets for "The mantle transition zone structure beneath the Pamir Plateau and western Tian Shan and adjacent regions "

description: The raw 3 component waveform data of XJ array used to compute receiver functions and further to generate detailed mantle transition zone structure together with other publicly available seismic data. Please note that this data is provided for reproduction purposes only.
DOI: 10.5281/zenodo.10725801
title: Datasets for "The mantle transition zone structure beneath the Pamir Plateau and western Tian Shan and adjacent regions "

description: The raw 3 component waveform data of XJ array used to compute receiver functions and further to generate detailed mantle transition zone structure together with other publicly available seismic data. Please note that this data is provided for reproduction purposes only.
DOI: 10.5281/zenodo.10032829
title: Datasets for "The mantle transition zone structure beneath the Pamir Plateau and western Tian Shan and adjacent regions "

description: The raw 3 component waveform data of XJ array used to compute receiver functions and further to generate detailed mantle transition zone structure together with other publicly available seismic data. Please note that this data is provided for reproduction purposes only.
DOI: 10.5281/zenodo.10032830
title: Datasets for "The mantle transition zone structure beneath the Pamir Plateau and western Tian Shan and adjacent regions "

description: The raw 3 component waveform data of XJ array used to compute receiver functions and further to generate detailed mantle transition zone structure together with other publicly available seismic data. Please note that this data is provided for reproduction purposes only.
DOI: 10.6084/m9.figshare.7806347
title: The improved antitumor efficacy of continuous intratumoral chemotherapy with cisplatin-loaded implants for the treatment of sarcoma 180 tumor-bearing mice

description: Cisplatin is the most commonly used antitumor drug in the chemotherapy of a variety of malignancies. However, the severe side effects and drug resistance limit its clinical application. The aim of this study was to develop PLGA-based cisplatin-loaded implants and evaluate the antitumor efficacy of continuous intratumoral chemotherapy with the implants. The cisplatin-loaded implants were prepared by the direct compression method and characterized regarding drug content, micromorphology, <i>in vitro</i> and <i>in vivo</i> drug release profiles. Furthermore, the antitumor activity of the implants was conducted in sarcoma 180 tumor-bearing mice. The SEM images showed smooth surface of the implants and the mean drug content of the tested implants was (37.7% ± 0.5%, w/w). Both <i>in vitro</i> and <i>in vivo</i> release profiles of the implants were characterized by initial burst release followed by the sustained-release of cisplatin. Intratumoral implantation of the cisplatin-loaded implants could effectively inhibit the tumor growth. Additionally, intratumoral chemotherapy with the implants significantly reduced the systemic toxicity compared with intravenous injection of cisplatin. It is worth noting that an increase in the dose of the implants led to a higher tumor suppression rate without additional systemic toxicity. These results demonstrated that cisplatin-loaded implants enhanced the antitumor efficacy and reduced the dose-related side effects in sarcoma 180 tumor-bearing mice.
DOI: 10.6084/m9.figshare.7806347.v1
title: The improved antitumor efficacy of continuous intratumoral chemotherapy with cisplatin-loaded implants for the treatment of sarcoma 180 tumor-bearing mice

description: Cisplatin is the most commonly used antitumor drug in the chemotherapy of a variety of malignancies. However, the severe side effects and drug resistance limit its clinical application. The aim of this study was to develop PLGA-based cisplatin-loaded implants and evaluate the antitumor efficacy of continuous intratumoral chemotherapy with the implants. The cisplatin-loaded implants were prepared by the direct compression method and characterized regarding drug content, micromorphology, <i>in vitro</i> and <i>in vivo</i> drug release profiles. Furthermore, the antitumor activity of the implants was conducted in sarcoma 180 tumor-bearing mice. The SEM images showed smooth surface of the implants and the mean drug content of the tested implants was (37.7% ± 0.5%, w/w). Both <i>in vitro</i> and <i>in vivo</i> release profiles of the implants were characterized by initial burst release followed by the sustained-release of cisplatin. Intratumoral implantation of the cisplatin-loaded implants could effectively inhibit the tumor growth. Additionally, intratumoral chemotherapy with the implants significantly reduced the systemic toxicity compared with intravenous injection of cisplatin. It is worth noting that an increase in the dose of the implants led to a higher tumor suppression rate without additional systemic toxicity. These results demonstrated that cisplatin-loaded implants enhanced the antitumor efficacy and reduced the dose-related side effects in sarcoma 180 tumor-bearing mice.
DOI: 10.6084/m9.figshare.8330684
title: Additional file 10: of Comprehensive dissection of transcript and metabolite shifts during seed germination and post-germination stages in poplar

description: Table S10. Genes and correlations involved in a targeted correlation network analysis (TCNA). (XLSX 14 kb)
DOI: 10.6084/m9.figshare.8330684.v1
title: Additional file 10: of Comprehensive dissection of transcript and metabolite shifts during seed germination and post-germination stages in poplar

description: Table S10. Genes and correlations involved in a targeted correlation network analysis (TCNA). (XLSX 14 kb)
DOI: 10.5281/zenodo.10725813
title: [IO Islamic 3106] يوسف و زليخا

description: Yûsuf-u-Zalîkhâ

This manuscript is now IO Islamic 1595 in the India Office collections.

[metadata: Hermann Ethé, Catalogue of Persian Manuscripts in the Library of the India Office, 2 vols. (Oxford: India Office, 1903): volume 1, number 3106 here with notations and hyperlinks].


1595

A slightly defective copy of the same.

One leaf is missing at the beginning of this copy.

The first bait, appearing here, corresponds to No. 184 (1593 above), fol. 3a, l. 8.

Dated A.H. 1103, Rajab (A.D. 1692, March-April).

No. 3106, ff. 1-156, 2 coll., each ll. 17; Shikasta, in most cases without any diacritical points and consequently vey difficult to read; size, 6½ in. by 3¾ in.
DOI: 10.5281/zenodo.10725814
title: [IO Islamic 3106] يوسف و زليخا

description: Yûsuf-u-Zalîkhâ

This manuscript is now IO Islamic 1595 in the India Office collections.

[metadata: Hermann Ethé, Catalogue of Persian Manuscripts in the Library of the India Office, 2 vols. (Oxford: India Office, 1903): volume 1, number 3106 here with notations and hyperlinks].


1595

A slightly defective copy of the same.

One leaf is missing at the beginning of this copy.

The first bait, appearing here, corresponds to No. 184 (1593 above), fol. 3a, l. 8.

Dated A.H. 1103, Rajab (A.D. 1692, March-April).

No. 3106, ff. 1-156, 2 coll., each ll. 17; Shikasta, in most cases without any diacritical points and consequently vey difficult to read; size, 6½ in. by 3¾ in.
DOI: 10.6084/m9.figshare.8330690
title: Additional file 1: of Comprehensive dissection of transcript and metabolite shifts during seed germination and post-germination stages in poplar

description: Table S1. Changes in fresh weight of poplar seeds during germination. (XLSX 15 kb)
DOI: 10.6084/m9.figshare.8330690.v1
title: Additional file 1: of Comprehensive dissection of transcript and metabolite shifts during seed germination and post-germination stages in poplar

description: Table S1. Changes in fresh weight of poplar seeds during germination. (XLSX 15 kb)
DOI: 10.6084/m9.figshare.8330699
title: Additional file 2: of Comprehensive dissection of transcript and metabolite shifts during seed germination and post-germination stages in poplar

description: Table S2. The average number of raw reads per library and matching results. (XLSX 17 kb)
DOI: 10.6084/m9.figshare.8330699.v1
title: Additional file 2: of Comprehensive dissection of transcript and metabolite shifts during seed germination and post-germination stages in poplar

description: Table S2. The average number of raw reads per library and matching results. (XLSX 17 kb)
DOI: 10.6084/m9.figshare.8330711
title: Additional file 3: of Comprehensive dissection of transcript and metabolite shifts during seed germination and post-germination stages in poplar

description: Table S3. IDs of genes in the 24 clusters. (XLSX 162 kb)
DOI: 10.6084/m9.figshare.8330711.v1
title: Additional file 3: of Comprehensive dissection of transcript and metabolite shifts during seed germination and post-germination stages in poplar

description: Table S3. IDs of genes in the 24 clusters. (XLSX 162 kb)
DOI: 10.6084/m9.figshare.8330720
title: Additional file 4: of Comprehensive dissection of transcript and metabolite shifts during seed germination and post-germination stages in poplar

description: Table S4. The relative abundance of transcription factors at different stages. (XLSX 17 kb)
DOI: 10.6084/m9.figshare.8330720.v1
title: Additional file 4: of Comprehensive dissection of transcript and metabolite shifts during seed germination and post-germination stages in poplar

description: Table S4. The relative abundance of transcription factors at different stages. (XLSX 17 kb)
DOI: 10.6084/m9.figshare.8330729
title: Additional file 5: of Comprehensive dissection of transcript and metabolite shifts during seed germination and post-germination stages in poplar

description: Table S5. Enriched pathway categories and mobilization trends in each module. (XLSX 22 kb)
DOI: 10.6084/m9.figshare.8330729.v1
title: Additional file 5: of Comprehensive dissection of transcript and metabolite shifts during seed germination and post-germination stages in poplar

description: Table S5. Enriched pathway categories and mobilization trends in each module. (XLSX 22 kb)
DOI: 10.6084/m9.figshare.13049326
title: Structural analysis, virtual screening and molecular simulation to identify potential inhibitors targeting 2'-O-ribose methyltransferase of SARS-CoV-2 coronavirus

description: SARS-CoV-2, an emerging coronavirus, has spread rapidly around the world, resulting in over ten million cases and more than half a million deaths as of July 1, 2020. Effective treatments and vaccines for SARS-CoV-2 infection do not currently exist. Previous studies demonstrated that nonstructural protein 16 (nsp16) of coronavirus is an S-adenosyl methionine (SAM)-dependent 2’-O-methyltransferase (2’-O-MTase) that has an important role in viral replication and prevents recognition by the host innate immune system. In the present study, we employed structural analysis, virtual screening, and molecular simulation approaches to identify clinically investigated and approved drugs which can act as promising inhibitors against nsp16 2′-O-MTase of SARS-CoV-2. Comparative analysis of primary amino acid sequences and crystal structures of seven human CoVs defined the key residues for nsp16 2-O’-MTase functions. Virtual screening and docking analysis ranked the potential inhibitors of nsp16 from more than 4,500 clinically investigated and approved drugs. Furthermore, molecular dynamics simulations were carried out on eight top candidates, including Hesperidin, Rimegepant, Gs-9667, and Sonedenoson, to calculate various structural parameters and understand the dynamic behavior of the drug-protein complexes. Our studies provided the foundation to further test and repurpose these candidate drugs experimentally and/or clinically for COVID-19 treatment. Communicated by Ramaswamy H. Sarma
DOI: 10.6084/m9.figshare.13049326.v1
title: Structural analysis, virtual screening and molecular simulation to identify potential inhibitors targeting 2'-O-ribose methyltransferase of SARS-CoV-2 coronavirus

description: SARS-CoV-2, an emerging coronavirus, has spread rapidly around the world, resulting in over ten million cases and more than half a million deaths as of July 1, 2020. Effective treatments and vaccines for SARS-CoV-2 infection do not currently exist. Previous studies demonstrated that nonstructural protein 16 (nsp16) of coronavirus is an S-adenosyl methionine (SAM)-dependent 2’-O-methyltransferase (2’-O-MTase) that has an important role in viral replication and prevents recognition by the host innate immune system. In the present study, we employed structural analysis, virtual screening, and molecular simulation approaches to identify clinically investigated and approved drugs which can act as promising inhibitors against nsp16 2′-O-MTase of SARS-CoV-2. Comparative analysis of primary amino acid sequences and crystal structures of seven human CoVs defined the key residues for nsp16 2-O’-MTase functions. Virtual screening and docking analysis ranked the potential inhibitors of nsp16 from more than 4,500 clinically investigated and approved drugs. Furthermore, molecular dynamics simulations were carried out on eight top candidates, including Hesperidin, Rimegepant, Gs-9667, and Sonedenoson, to calculate various structural parameters and understand the dynamic behavior of the drug-protein complexes. Our studies provided the foundation to further test and repurpose these candidate drugs experimentally and/or clinically for COVID-19 treatment. Communicated by Ramaswamy H. Sarma
DOI: 10.6084/m9.figshare.8330738
title: Additional file 6: of Comprehensive dissection of transcript and metabolite shifts during seed germination and post-germination stages in poplar

description: Table S6. High-connectivity transcription factors. (XLSX 16 kb)
DOI: 10.6084/m9.figshare.8330738.v1
title: Additional file 6: of Comprehensive dissection of transcript and metabolite shifts during seed germination and post-germination stages in poplar

description: Table S6. High-connectivity transcription factors. (XLSX 16 kb)
DOI: 10.6084/m9.figshare.8330744
title: Additional file 7: of Comprehensive dissection of transcript and metabolite shifts during seed germination and post-germination stages in poplar

description: Table S7. Brown module and green module functional gene IDs and connectivity. (XLSX 48 kb)
DOI: 10.6084/m9.figshare.8330744.v1
title: Additional file 7: of Comprehensive dissection of transcript and metabolite shifts during seed germination and post-germination stages in poplar

description: Table S7. Brown module and green module functional gene IDs and connectivity. (XLSX 48 kb)
DOI: 10.6084/m9.figshare.8330750
title: Additional file 8: of Comprehensive dissection of transcript and metabolite shifts during seed germination and post-germination stages in poplar

description: Table S8. Primary metabolite changes during seed germination and post germination. (XLSX 10 kb)
DOI: 10.6084/m9.figshare.8330750.v1
title: Additional file 8: of Comprehensive dissection of transcript and metabolite shifts during seed germination and post-germination stages in poplar

description: Table S8. Primary metabolite changes during seed germination and post germination. (XLSX 10 kb)
DOI: 10.6084/m9.figshare.8330753
title: Additional file 9: of Comprehensive dissection of transcript and metabolite shifts during seed germination and post-germination stages in poplar

description: Table S9. Primary metabolism-related gene profiling. (XLSX 22 kb)
DOI: 10.6084/m9.figshare.8330753.v1
title: Additional file 9: of Comprehensive dissection of transcript and metabolite shifts during seed germination and post-germination stages in poplar

description: Table S9. Primary metabolism-related gene profiling. (XLSX 22 kb)
DOI: 10.5281/zenodo.10725829
title: [IO Islamic 3391] يوسف و زليخا

description: Yûsuf-u-Zalîkhâ

This manuscript is now IO Islamic 1596 in the India Office collections.

[metadata: Hermann Ethé, Catalogue of Persian Manuscripts in the Library of the India Office, 2 vols. (Oxford: India Office, 1903): volume 1, number 3391 here with notations and hyperlinks].


1596

A fragment of the same.

This copy goes down to the third dream of Zalîkhâ, in which she saw Yûsuf. The last bait corresponds to No. 184 (1593 above), fol. 40b, l. 5. 

No date. Modern transcript.

No.3391, olim 14. J. 19, ff. 1-53, 2 coll., each ll. 14; Nasta’lîḳ; size, 77/8 in. by 45/8 in.
DOI: 10.5281/zenodo.10725830
title: [IO Islamic 3391] يوسف و زليخا

description: Yûsuf-u-Zalîkhâ

This manuscript is now IO Islamic 1596 in the India Office collections.

[metadata: Hermann Ethé, Catalogue of Persian Manuscripts in the Library of the India Office, 2 vols. (Oxford: India Office, 1903): volume 1, number 3391 here with notations and hyperlinks].


1596

A fragment of the same.

This copy goes down to the third dream of Zalîkhâ, in which she saw Yûsuf. The last bait corresponds to No. 184 (1593 above), fol. 40b, l. 5. 

No date. Modern transcript.

No.3391, olim 14. J. 19, ff. 1-53, 2 coll., each ll. 14; Nasta’lîḳ; size, 77/8 in. by 45/8 in.
DOI: 10.6084/m9.figshare.13049446
title: Integrated analysis of mRNA and microRNA expression profiles reveals differential transcriptome signature in ischaemic and dilated cardiomyopathy induced heart failure

description: Cardiac remodelling is widely accepted as a common characteristic for many heart diseases, especially in heart failure (HF). Ischaemic cardiomyopathy (ICM) and dilated cardiomyopathy (DCM) are associated with cardiac remodelling. Both mRNA and microRNA are potential diagnostic markers and therapeutic targets of cardiac remodelling in HF. However, the mechanisms of microRNA-mRNA joint regulation in HF are still unclear. In this study, 3 gene expression profiles from patients with and without HF were analysed to harvest shared differentially expressed genes (microRNA and mRNA) with significant major biological function. Moreover, key genes highly related to ICM and DCM-induced HF were screened out through a Weighted Genes Co-Expression Network Analysis (WGCNA). Based on microRNA-mRNA analysis, several microRNAs and target genes were identified. Combined with pathway analysis, we found that miR-542-3p and its target gene CILP were likely involved in the regulation of TGF-β signalling pathway in ICM induced HF. Collectively, the microRNA–mRNA interaction network analysis revealed that miR-542-3p-CILP as mediator of TGF-β signalling pathway might be a new mechanism to mediate ICM induced HF. This study provides certain novel targets for diagnosis and therapeutic treatment of ICM- and DCM-induced HF.
DOI: 10.6084/m9.figshare.13049446.v1
title: Integrated analysis of mRNA and microRNA expression profiles reveals differential transcriptome signature in ischaemic and dilated cardiomyopathy induced heart failure

description: Cardiac remodelling is widely accepted as a common characteristic for many heart diseases, especially in heart failure (HF). Ischaemic cardiomyopathy (ICM) and dilated cardiomyopathy (DCM) are associated with cardiac remodelling. Both mRNA and microRNA are potential diagnostic markers and therapeutic targets of cardiac remodelling in HF. However, the mechanisms of microRNA-mRNA joint regulation in HF are still unclear. In this study, 3 gene expression profiles from patients with and without HF were analysed to harvest shared differentially expressed genes (microRNA and mRNA) with significant major biological function. Moreover, key genes highly related to ICM and DCM-induced HF were screened out through a Weighted Genes Co-Expression Network Analysis (WGCNA). Based on microRNA-mRNA analysis, several microRNAs and target genes were identified. Combined with pathway analysis, we found that miR-542-3p and its target gene CILP were likely involved in the regulation of TGF-β signalling pathway in ICM induced HF. Collectively, the microRNA–mRNA interaction network analysis revealed that miR-542-3p-CILP as mediator of TGF-β signalling pathway might be a new mechanism to mediate ICM induced HF. This study provides certain novel targets for diagnosis and therapeutic treatment of ICM- and DCM-induced HF.
DOI: 10.6084/m9.figshare.13049452
title: Figure 6 raw data from Synthesis of mesoporous silicate molecular sieves by aerosol-assisted method for loading and release of drug

description: 10.6084/m9.figshare.12782792
DOI: 10.6084/m9.figshare.13049452.v1
title: Figure 6 raw data from Synthesis of mesoporous silicate molecular sieves by aerosol-assisted method for loading and release of drug

description: 10.6084/m9.figshare.12782792
DOI: 10.6084/m9.figshare.13049455
title: Figure 8 raw data from Synthesis of mesoporous silicate molecular sieves by aerosol-assisted method for loading and release of drug

description: 10.6084/m9.figshare.12782801
DOI: 10.6084/m9.figshare.13049455.v1
title: Figure 8 raw data from Synthesis of mesoporous silicate molecular sieves by aerosol-assisted method for loading and release of drug

description: 10.6084/m9.figshare.12782801
DOI: 10.6084/m9.figshare.13049458
title: Figure 4 raw data from Synthesis of mesoporous silicate molecular sieves by aerosol-assisted method for loading and release of drug

description: 10.6084/m9.figshare.12782804
DOI: 10.6084/m9.figshare.13049458.v1
title: Figure 4 raw data from Synthesis of mesoporous silicate molecular sieves by aerosol-assisted method for loading and release of drug

description: 10.6084/m9.figshare.12782804
DOI: 10.6084/m9.figshare.13049461
title: Figure 7 raw data from Synthesis of mesoporous silicate molecular sieves by aerosol-assisted method for loading and release of drug

description: 10.6084/m9.figshare.12782798
DOI: 10.6084/m9.figshare.13049461.v1
title: Figure 7 raw data from Synthesis of mesoporous silicate molecular sieves by aerosol-assisted method for loading and release of drug

description: 10.6084/m9.figshare.12782798
DOI: 10.6084/m9.figshare.13049464
title: Figure 5 raw data from Synthesis of mesoporous silicate molecular sieves by aerosol-assisted method for loading and release of drug

description: 10.6084/m9.figshare.12782786
DOI: 10.6084/m9.figshare.13049464.v1
title: Figure 5 raw data from Synthesis of mesoporous silicate molecular sieves by aerosol-assisted method for loading and release of drug

description: 10.6084/m9.figshare.12782786