cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6075/j0rr1wrv
title: Data from: The Ocean’s Elevator: Evolution of the air-seawater interface during a small-scale algal bloom. In Center for Aerosol Impacts on Chemistry of the Environment (CAICE)

description: Publication abstract: The composition and lifetime of sea spray aerosols are driven by the molecular and biological complexity of the air−seawater interface. We explore in situ the surface properties of marine algal bloom diatom monocultures by utilizing surface techniques of Brewster angle microscopy (BAM) imaging, vibrational sum-frequency generation (SFG) spectroscopy, and infrared reflection−absorption spectroscopy (IRRAS). Over the course of the bloom, the marine algae produce surface-active biogenic molecules that temporally partition to the topmost interfacial layers and are selectively probed through surface imaging and spectroscopic measurements. BAM images show morphological structural changes and heterogeneity in the interfacial films with increasing density of surface-active biogenic molecules. Film thickness calculations quantified the average surface thickness of a productive bloom over time. The image results reveal an ∼5 nm thick surface region in the late stages of the bloom, which correlates with typical sea surface nanolayer thicknesses. Our surface-specific SFG spectroscopy results show significant diminishing in the intensity of the dangling OH bond of surface water molecules consistent with organic molecules partitioning and replacing water at the air−seawater interface as the algal bloom progresses. Interestingly, we observe a new broad band appear between 3500 and 3600 cm−1 in the late stages of the bloom that is attributed to weak hydrogen bonding interactions of water to the surface-active biogenic matter. IRRAS confirms the presence of organic molecules at the surface as we observe an increasing intensity of vibrational alkyl modes and the appearance of a proteinaceous amide band over time. Our work shows the often overlooked but vast potential of tracking changes in the interfacial regime of small-scale laboratory marine algal blooms. By coupling surface imaging and vibrational spectroscopies to complex, time-evolving, marine-relevant systems, we provide additional insight into unraveling the temporal complexity of sea spray aerosol compositions.
DOI: 10.6084/m9.figshare.22220692.v1
title: Data for: Institutional repositories measurably increase the FAIRness of research outputs: Actionable data for librarians

description: These data and code support work presented at the ER&L 2023 conference on March 6, 2023 in Austin, TX, USA.<b>Presentation description:</b><br>Datasets and non-traditional research outputs are a growing use case for institutional repositories. We quantify how much FAIRer institutional repository outputs are and examine other benefits like reuse metrics and Altmetrics. Librarians can use this to quantify the value of their role and their institution's investment in the repository.<b>Methods and file description:</b><br>Metadata was harvested through Figshare's API (https://docs.figshare.com). Records publicly shared on figshare.com by researchers affiliated with a US based institution were found through figshare.com profiles registered using an email using an institution domain. This information is not public and the affiliation information was removed from the ANALYSIS-DATASET. All other information is publicly available through the API. The compressed file called 'additional-datasets.zip' contains the author, categories, funder, and file information for the researcher records and institution records. The Jupyter Notebook harvests metadata, creates datasets, produces figures used in the presentation, and creates the dataset used for the negative binomial analysis in R. The data-for-R.R file performs the negative binomial analysis which shows relative differences in several metrics for the groups of records.Altmetric data presented at the conference are not public and not included in this dataset.
DOI: 10.6084/m9.figshare.22220692
title: Data for: Institutional repositories measurably increase the FAIRness of research outputs: Actionable data for librarians

description: These data and code support work presented at the ER&L 2023 conference on March 6, 2023 in Austin, TX, USA.<b>Presentation description:</b><br>Datasets and non-traditional research outputs are a growing use case for institutional repositories. We quantify how much FAIRer institutional repository outputs are and examine other benefits like reuse metrics and Altmetrics. Librarians can use this to quantify the value of their role and their institution's investment in the repository.<b>Methods and file description:</b><br>Metadata was harvested through Figshare's API (https://docs.figshare.com). Records publicly shared on figshare.com by researchers affiliated with a US based institution were found through figshare.com profiles registered using an email using an institution domain. This information is not public and the affiliation information was removed from the ANALYSIS-DATASET. All other information is publicly available through the API. The compressed file called 'additional-datasets.zip' contains the author, categories, funder, and file information for the researcher records and institution records. The Jupyter Notebook harvests metadata, creates datasets, produces figures used in the presentation, and creates the dataset used for the negative binomial analysis in R. The data-for-R.R file performs the negative binomial analysis which shows relative differences in several metrics for the groups of records.Altmetric data presented at the conference are not public and not included in this dataset.
DOI: 10.15468/dl.2u8kve
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 {
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen)"
 ]
 }
 }
 ]
 },
 "SpeciesKey is Broelemanneuma gayi Demange, 1968",
 "Year is greater than or equal to 2004",
 "Year is less than or equal to 2023"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0080853-240626123714530/datasets/export for details.
DOI: 10.5517/ccdc.csd.cc2fcj9n
title: CCDC 2245401: Experimental Crystal Structure Determination

description: Related Article: Wanlan Su, Jide Zhu, Yu Chen, Xu Zhang, Weihua Qiu, Kai Yang, Peiyuan Yu, Qiuling Song |2024|Nature Chemistry|16|1312|doi:10.1038/s41557-024-01505-0
description: Related Article: Kai Yang|2023|CSD Communication|||
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2fg3vw
title: CCDC 2247898: Experimental Crystal Structure Determination

description: Related Article: Bo-Lun Zhang, Pei-Pei Zhang, Ai-Yun Ni, Jian-Jun Zhang, Hui-Yu Wang, Ke-Xin Feng, Shuqin Liu, Zongbin Zhao, Chunying Duan|2023|Adv. Opt. Mater.|11|2300717|doi:10.1002/adom.202300717
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2g6tj1
title: CCDC 2270673: Experimental Crystal Structure Determination

description: Related Article: Zhe Feng, Yuanyuan Li, Siyi Chen, Jin Li, Tianxiang Wu, Yanyun Ying, Junyan Zheng, Yuhuang Zhang, Jianquan Zhang, Xiaoxiao Fan, Xiaoming Yu, Dan Zhang, Ben Zhong Tang, Jun Qian |2023|Nat.Commun.|14|5017|doi:10.1038/s41467-023-40728-6
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2hlc9s
title: CCDC 2311555: Experimental Crystal Structure Determination

description: Related Article: Masahiro Matsuoka, Koichi Nagata, Ryoma Ohno, Tsukasa Matsuo, Hisako Hashimoto|2024|Chem.Lett.|53|upae002|doi:10.1093/chemle/upae002
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2hlcwc
title: CCDC 2311573: Experimental Crystal Structure Determination

description: Related Article: Masahiro Matsuoka, Koichi Nagata, Ryoma Ohno, Tsukasa Matsuo, Hisako Hashimoto|2024|Chem.Lett.|53|upae002|doi:10.1093/chemle/upae002
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.15468/dl.spdqpy
title: Occurrence Download

description: A dataset containing 29906 species occurrences available in GBIF matching the query:
{
 "and" : [
 {
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen)"
 ]
 }
 }
 ]
 },
 "SpeciesKey is Hippodamia variegata (Goeze, 1777)",
 "Year is greater than or equal to 2004",
 "Year is less than or equal to 2023"
 ]
}

 The dataset includes 29906 records from 579 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0080854-240626123714530/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.czd4s9
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 {
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen)"
 ]
 }
 }
 ]
 },
 "SpeciesKey is Broelemanneuma furcatum Ribaut, 1913",
 "Year is greater than or equal to 2004",
 "Year is less than or equal to 2023"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0080856-240626123714530/datasets/export for details.
DOI: 10.15468/dl.tyjyab
title: Occurrence Download

description: A dataset containing 55 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Human Observation",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Absent",
 "TaxonKey is Poecilia sphenops Valenciennes, 1846"
 ]
}

 The dataset includes 55 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0080857-240626123714530/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.4121/5156d8f6-4a7e-4145-a516-78a8a3830af9
title: Smart SATA Driver test data

description: This data set provides the test results of a modular robotic driver for SATA laparoscopic instruments: The Smart SATA Driver.The Smart SATA Driver is a cableless, modular and re-usable robotic driver that incorporates sensorless feedback technology to articulate SATA laparoscopic instruments.<br>This data set incorporates:The software scripts to control the Smart SATA Driver with a remote controller (including smart sensing features):SATA_MEGA_RECEIVER_09.inoSATA_MEGA_TRANSMITTER_03.inoThe electrical diagrams of the controller (remote controller) and receiver (the Smart SATA Driver)Circuit_Diagram_Receiver_Smart_SATA_Driver.pngCircuit_Diagram_Transmitter_Smart_SATA_Driver.pngThe test data of the Smart SATA Driver assembly testassembly_disassembly_time_recordings.xlsxnasa_tlx_results.xlsxREADME_assembly_test.txtThe test data of the coupling test of the modular parts of the Smart SATA Driver for each experimental/test conditionEC1_MU-SB.xlsxEC2_MU-SB-GB.xlsxEC3_MU-SB-GBwI.xlsxEC4_MUwSB-GB.xlsxEC5_MUwSB-GBwI.xlsxREADME_coupling_test.txtThe test data of the force tests of each Degree of Freedom of the Smart SATA Driver in straight and bent instrument positionbending_force_10x_straight.xlsxbending_force_10x_bent.xlsxshaft_rotation_10x_straight.xlsxshaft_rotation_10x_bent .xlsxtip_force_10x_straight.xlsxtip_force_10x_bent.xlsxtip_rotation_10x_straight.txttip_rotation_10x_bent.txtREADME_force_test.txtThe test data of the StallGuard force test (force limiting test using back electromotive force sensing with StallGuard technology in TMC2209 Stepper Drivers)SG_testdata.xlsxREADME_stallguard_force _test.txt<br>
DOI: 10.4121/5156d8f6-4a7e-4145-a516-78a8a3830af9.v1
title: Smart SATA Driver test data

description: This data set provides the test results of a modular robotic driver for SATA laparoscopic instruments: The Smart SATA Driver.The Smart SATA Driver is a cableless, modular and re-usable robotic driver that incorporates sensorless feedback technology to articulate SATA laparoscopic instruments.<br>This data set incorporates:The software scripts to control the Smart SATA Driver with a remote controller (including smart sensing features):SATA_MEGA_RECEIVER_09.inoSATA_MEGA_TRANSMITTER_03.inoThe electrical diagrams of the controller (remote controller) and receiver (the Smart SATA Driver)Circuit_Diagram_Receiver_Smart_SATA_Driver.pngCircuit_Diagram_Transmitter_Smart_SATA_Driver.pngThe test data of the Smart SATA Driver assembly testassembly_disassembly_time_recordings.xlsxnasa_tlx_results.xlsxREADME_assembly_test.txtThe test data of the coupling test of the modular parts of the Smart SATA Driver for each experimental/test conditionEC1_MU-SB.xlsxEC2_MU-SB-GB.xlsxEC3_MU-SB-GBwI.xlsxEC4_MUwSB-GB.xlsxEC5_MUwSB-GBwI.xlsxREADME_coupling_test.txtThe test data of the force tests of each Degree of Freedom of the Smart SATA Driver in straight and bent instrument positionbending_force_10x_straight.xlsxbending_force_10x_bent.xlsxshaft_rotation_10x_straight.xlsxshaft_rotation_10x_bent .xlsxtip_force_10x_straight.xlsxtip_force_10x_bent.xlsxtip_rotation_10x_straight.txttip_rotation_10x_bent.txtREADME_force_test.txtThe test data of the StallGuard force test (force limiting test using back electromotive force sensing with StallGuard technology in TMC2209 Stepper Drivers)SG_testdata.xlsxREADME_stallguard_force _test.txt<br>
DOI: 10.15468/dl.8avcfg
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 {
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen)"
 ]
 }
 }
 ]
 },
 "SpeciesKey is Rothenbuehleria tirolensis Verhoeff, 1900",
 "Year is greater than or equal to 2004",
 "Year is less than or equal to 2023"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0080859-240626123714530/datasets/export for details.
DOI: 10.15468/dl.4cr944
title: Occurrence Download

description: A dataset containing 29906 species occurrences available in GBIF matching the query:
{
 "and" : [
 {
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen)"
 ]
 }
 }
 ]
 },
 "SpeciesKey is Hippodamia variegata (Goeze, 1777)",
 "Year is greater than or equal to 2004",
 "Year is less than or equal to 2023"
 ]
}

 The dataset includes 29906 records from 579 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0080858-240626123714530/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.twr523
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 {
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen)"
 ]
 }
 }
 ]
 },
 "SpeciesKey is Rothenbuehleria minima (Rothenbühler, 1899)",
 "Year is greater than or equal to 2004",
 "Year is less than or equal to 2023"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0080861-240626123714530/datasets/export for details.
DOI: 10.15468/dl.fug42p
title: Occurrence Download

description: A dataset containing 29906 species occurrences available in GBIF matching the query:
{
 "and" : [
 {
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen)"
 ]
 }
 }
 ]
 },
 "SpeciesKey is Hippodamia variegata (Goeze, 1777)",
 "Year is greater than or equal to 2004",
 "Year is less than or equal to 2023"
 ]
}

 The dataset includes 29906 records from 579 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0080862-240626123714530/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.7270/q2sb499g
title: BindingDB Entry 50010887: Bioreducible Phosphonoamidate Pro-drug Inhibitor of Enolase: Proof of Concept Study.

description: Small molecule binding data for protein Alpha-enolase, Uniprot P06733
DOI: 10.7270/q2sb49bx
title: BindingDB Entry 50011171: The signal peptide as a new target for drug design.

description: Small molecule binding data for protein Sortilin and T-cell surface glycoprotein CD4, Uniprot P01730 and Q99523
DOI: 10.7270/q2sb49cc
title: BindingDB Entry 50011519: Investigation of synergistic antimicrobial effects of the drug combinations of meropenem and 1,2-benzisoselenazol-3(2H)-one derivatives on carbapenem-resistant Enterobacteriaceae producing NDM-1.

description: Small molecule binding data for protein Metallo-beta-lactamase type 2, Uniprot C7C422
DOI: 10.7270/q2sb49dt
title: BindingDB Entry 50012141: Synthesis and biological activities of simplified aplysiatoxin analogs focused on the CH/π interaction.

description: Small molecule binding data for protein Protein kinase C alpha type and Protein kinase C delta type, Uniprot P20444 and P28867
DOI: 10.7270/q2sb49f8
title: BindingDB Entry 50012760: Improving NK1R-targeted gene delivery of stearyl-antimicrobial peptide CAMEL by conjugating it with substance P.

description: Small molecule binding data for protein Substance-P receptor, Uniprot P25103
DOI: 10.7270/q2sb49gq
title: BindingDB Entry 50013417: Neuroprotective effects of prenylated flavanones isolated from Dalea species, in vitro and in silico studies.

description: Small molecule binding data for protein Acetylcholinesterase, Uniprot P22303
DOI: 10.7270/q2sb49h5
title: BindingDB Entry 50014051: Discovery of 4-aminopyrimidine analogs as highly potent dual P70S6K/Akt inhibitors.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GSC2, Cytochrome P450 1A2, Cytochrome P450 2B6, Cytochrome P450 2C19, Cytochrome P450 2C8, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A4, and RAC-alpha/RAC-beta/RAC-gamma serine/threonine-protein kinase, Uniprot P05177, P08684, P10632, P10635, P11712, P20813, P31749, P31751, P33261, P40989, and Q9Y243
DOI: 10.7270/q2sb49jm
title: BindingDB Entry 50014407: Phosphinanes and Azaphosphinanes as Potent and Selective Inhibitors of Activated Thrombin-Activatable Fibrinolysis Inhibitor (TAFIa).

description: Small molecule binding data for protein Carboxypeptidase B, Carboxypeptidase B2, and Carboxypeptidase N catalytic chain, Uniprot P15086, P15169, Q96IY4, and Q9EQV9
DOI: 10.7270/q2sb49k2
title: BindingDB Entry 50014709: Natural inspired piperine-based sulfonamides and carboxylic acids as carbonic anhydrase inhibitors: Design, synthesis and biological evaluation.

description: Small molecule binding data for protein Carbonic anhydrase 1, Carbonic anhydrase 12, Carbonic anhydrase 2, and Carbonic anhydrase 9, Uniprot O43570, P00915, P00918, and Q16790
DOI: 10.7270/q2sf307h
title: BindingDB Entry 9303: Isoquinoline derivatives and use thereof

description: Small molecule binding data for protein Sodium channel protein type 9 subunit alpha, Uniprot Q15858
DOI: 10.7270/q2sf308z
title: BindingDB Entry 9690: LRRK2 inhibitors and methods of making and using the same

description: Small molecule binding data for protein Leucine-rich repeat serine/threonine-protein kinase 2 [1326-2527,A2016T,G2019S], Leucine-rich repeat serine/threonine-protein kinase 2 [1326-2527,A2016T], Leucine-rich repeat serine/threonine-protein kinase 2 [1326-2527,G2019S], and Leucine-rich repeat serine/threonine-protein kinase 2 [1326-2527], Uniprot Q5S007
DOI: 10.7270/q2sf309d
title: BindingDB Entry 10077: Substituted pyrrolo[2,1-f][1,2,4]triazines as kinase inhibitors

description: Small molecule binding data for protein Tyrosine-protein kinase BTK and Tyrosine-protein kinase JAK3, Uniprot P52333 and Q06187
DOI: 10.7270/q2sf30bv
title: BindingDB Entry 10286: Aminocarbamoyl compounds for the treatment of viral infections

description: Small molecule binding data for protein Orf1a protein and Replicase polyprotein 1ab, Uniprot A0A1L2E0X0, P0C6X1, P0C6X6, P0C6X7, and P0DTD1
DOI: 10.7270/q2sf30c9
title: BindingDB Entry 10464: Bicyclic fused pyridine compounds as inhibitors of TAM kinases

description: Small molecule binding data for protein Tyrosine-protein kinase Mer, Tyrosine-protein kinase receptor TYRO3, and Tyrosine-protein kinase receptor UFO, Uniprot P30530, Q06418, and Q12866
DOI: 10.7270/q2sf30dr
title: BindingDB Entry 10673: Therapeutic compounds and uses thereof

description: Small molecule binding data for protein Vascular endothelial growth factor receptor 2, Uniprot P35968
DOI: 10.7270/q2sf30f6
title: BindingDB Entry 50006845: Leucoflavonine, a new bioactive racemic flavoalkaloid from the leaves of Leucosceptrum canum.

description: Small molecule binding data for protein Acetylcholinesterase, Uniprot P22303
DOI: 10.7270/q2sf30gn
title: BindingDB Entry 50007446: Fluorescence Labeling of Neurotensin(8-13) via Arginine Residues Gives Molecular Tools with High Receptor Affinity.

description: Small molecule binding data for protein Neurotensin receptor type 1 and Neurotensin receptor type 2, Uniprot O95665 and P30989
DOI: 10.7270/q2sf30h3
title: BindingDB Entry 50008054: Multistage Screening Reveals 3-Substituted Indolin-2-one Derivatives as Novel and Isoform-Selective c-Jun N-terminal Kinase 3 (JNK3) Inhibitors: Implications to Drug Discovery for Potential Treatment of Neurodegenerative Diseases.

description: Small molecule binding data for protein Epidermal growth factor receptor, Mitogen-activated protein kinase 10, Mitogen-activated protein kinase 8, Mitogen-activated protein kinase 9, Tyrosine-protein kinase ABL1, and Tyrosine-protein kinase Yes, Uniprot P00519, P00533, P07947, P45983, P45984, and P53779
DOI: 10.7270/q2sf30jj
title: BindingDB Entry 50008680: Acrylamide Functional Group Incorporation Improves Drug-like Properties: An Example with EGFR Inhibitors.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GSC2 and Epidermal growth factor receptor, Uniprot P00533 and P40989