cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.14054007
title: Integrating efficacy and safety of vedolizumab compared with other advanced therapies to assess net clinical benefit of ulcerative colitis treatments: a network meta-analysis

description: Because only one head-to-head randomized trial of biologics for moderate-to-severe UC has been performed, indirect treatment comparisons remain important. This systematic review and network meta-analysis examined efficacy and safety of biologics and tofacitinib for moderate-to-severe UC, using vedolizumab as reference. Relevant studies (N = 19) of vedolizumab, adalimumab, infliximab, golimumab, ustekinumab, and tofacitinib were identified. Study design differences were addressed by assessing efficacy outcomes conditional on response at maintenance initiation. Primary analysis used fixed-effect models to estimate odds ratios for efficacy and safety endpoints. Compared with vedolizumab 300 mg, adalimumab 160/80 mg was associated with less clinical remission (odds ratio, 0.69 [95% credible interval, 0.54–0.88]), and infliximab 5 mg/kg was associated with more clinical remission (1.67 [1.16–2.42]) and response (1.63 [1.15–2.30]). Adalimumab 40 mg, golimumab 50 mg, and ustekinumab 90 mg Q12W had significantly lower clinical remission rates during maintenance (0.62 [0.45–0.86], 0.55 [0.32–0.95], and 0.59 [0.35–0.99]) versus vedolizumab 300 mg Q8W. Response results were similar. Tofacitinib 10 mg had the highest maintenance treatment efficacy estimates and highest infection risk. Network meta-analysis and novel integrated benefit-risk analysis suggest a potentially favorable efficacy-safety balance for vedolizumab vs adalimumab and other advanced UC therapies.
DOI: 10.6084/m9.figshare.14054007.v2
title: Integrating efficacy and safety of vedolizumab compared with other advanced therapies to assess net clinical benefit of ulcerative colitis treatments: a network meta-analysis

description: <b>Objectives</b>: Because only one head-to-head randomized trial of biologics for moderate-to-severe UC has been performed, indirect treatment comparisons remain important. This systematic review and network meta-analysis examined efficacy and safety of biologics and tofacitinib for moderate-to-severe UC, using vedolizumab as reference. <b>Methods</b>: Relevant studies (N = 19) of vedolizumab, adalimumab, infliximab, golimumab, ustekinumab, and tofacitinib were identified. Study design differences were addressed by assessing efficacy outcomes conditional on response at maintenance initiation. Primary analysis used fixed-effect models to estimate odds ratios for efficacy and safety endpoints. <b>Results</b>: Compared with vedolizumab 300 mg, adalimumab 160/80 mg was associated with less clinical remission (odds ratio, 0.69 [95% credible interval, 0.54–0.88]), and infliximab 5 mg/kg was associated with more clinical remission (1.67 [1.16–2.42]) and response (1.63 [1.15–2.30]). Adalimumab 40 mg, golimumab 50 mg, and ustekinumab 90 mg Q12W had significantly lower clinical remission rates during maintenance (0.62 [0.45–0.86], 0.55 [0.32–0.95], and 0.59 [0.35–0.99]) versus vedolizumab 300 mg Q8W. Response results were similar. Tofacitinib 10 mg had the highest maintenance treatment efficacy estimates and highest infection risk. <b>Conclusion</b>: Network meta-analysis and novel integrated benefit-risk analysis suggest a potentially favorable efficacy-safety balance for vedolizumab vs adalimumab and other advanced UC therapies.
DOI: 10.5281/zenodo.5720754
title: Comparing the acceptability of total diet replacement and food-based low-calorie diets for type 2 diabetes remission amongst Southeast Asians: a public and patient involvement activity

description: Document including information pack sent to participants prior to PPIE activity meetings. COREQ checklist included
DOI: 10.6084/m9.figshare.21450009
title: taci_hg19.bed

description: Working test of BED data file
DOI: 10.6084/m9.figshare.21450009.v1
title: taci_hg19.bed

description: Working test of BED data file
DOI: 10.6084/m9.figshare.21451329
title: bigBedExample.bb

description: Example of bigBed file
DOI: 10.6084/m9.figshare.21451329.v1
title: bigBedExample.bb

description: Example of bigBed file
DOI: 10.6084/m9.figshare.21446823.v1
title: QTL mapping and transcriptome profiling reveals that both target-site resistance and increased detoxification confer resistance to the pyrethroid bifenthrin in the spider mite Tetranychus urticae

description: This project investigated bifenthrin resistance in the two-spotted spider mite <em>Tetranychus urticae</em>. Bulked segregant analysis (BSA) based QTL-mapping experiments with the pyrethroid resistant strain MR-VLi were performed to identify genomic loci (QTLs) underlying bifenthrin resistance. Moreover, this project also aimed to investigate gene expression changes associated with pyrethroid resistance via differential gene expression analysis on a panel of bifenthrin resistant and susceptible strains (ES1, ROS-IT, UK4, IT3, RO1, MR-VL and El Juan). The analysis was based on (partially new) RNAseq data and genomic DNAseq data released to NCBI under accessions PRJNA896577 and PRJNA895330 respectively. Datasets released here include Data S1: genomic VCF (gzipped) used as input for the RUN_BSA1.02.py script available at https://github.com/rmclarklab/BSA (Kurlovs et al. 2019, PMID: 31499416). Data S2: raw RNA-seq read counts on a per-gene basis for the strains ES1, ROS-IT, UK4, IT3, RO1, MR-VL and El Juan with 4 replicates for each strain.
DOI: 10.6084/m9.figshare.19733860
title: muDmelDsim

description: The phased haplotypes for three populations: the West African <em>D. melanogaster</em> (dmeA), the European <em>D. melanogaster </em>(dmeE) and the European<em> D. simulans</em> (dsim). There are 24 haplotypes for each population. File names: 'population_family_sex_haplotypes.fa.fz'. <br> !! if you want to use the data for publication, please contact wang.yiguan@gmail.com
DOI: 10.3886/2cgn-nj39
title: Cabo Verde Compact II - Land Management for Investment: Final Analysis Report
DOI: 10.3886/rqxz-vn22
title: Mali Compact - Alatona Irrigation: Design Report - Addendum
DOI: 10.3886/fxdm-yr93
title: Mali Compact - Alatona Irrigation: Design Report - Addendum
DOI: 10.5281/zenodo.7271945
title: Training Deep Learning Models to Estimate SWAT Parameters using Streamflow Observations

description: This folder provides the simulation and observational data Simulation data using SWAT (1000 realz)<br> Train, Val, and Test splits (80/10/10)<br> Observational data for ARW (WY2000-2016)
DOI: 10.5281/zenodo.7271944
title: Training Deep Learning Models to Estimate SWAT Parameters using Streamflow Observations

description: This folder provides the simulation and observational data Simulation data using SWAT (1000 realz)<br> Train, Val, and Test splits (80/10/10)<br> Observational data for ARW (WY2000-2016)
DOI: 10.3886/29pb-e144
title: Mali Compact - Alatona Irrigation: Interim Analysis Report
DOI: 10.3886/w4ej-7q09
title: Mali Compact - Alatona Irrigation: Interim Analysis Report
DOI: 10.5281/zenodo.5873264
title: Sampling Rare Event Energy Landscapes via Birth-Death Augmented Dynamics

description: Archive with data supporting the paper "Sampling Rare Event Energy Landscapes via Birth-Death Augmented Dynamics" and the related PhD thesis by B. Pampel
DOI: 10.5281/zenodo.5873265
title: Sampling Rare-Event Energy Landscapes via a Birth-Death Process

description: Archive with data supporting the paper "Sampling Rare-Event Energy Landscapes via a Birth-Death Process" and the related PhD thesis by B. Pampel
DOI: 10.5281/zenodo.7019132
title: Sampling Rare Event Energy Landscapes via Birth-Death Augmented Dynamics

description: Archive with data supporting the paper "Sampling Rare Event Energy Landscapes via Birth-Death Augmented Dynamics" and the related PhD thesis by B. Pampel
DOI: 10.5281/zenodo.7186238
title: Sampling Rare Event Energy Landscapes via Birth-Death Augmented Dynamics

description: Archive with data supporting the paper "Sampling Rare Event Energy Landscapes via Birth-Death Augmented Dynamics" and the related PhD thesis by B. Pampel
DOI: 10.5281/zenodo.5851773
title: Improving the Efficiency of Variationally Enhanced Sampling with Wavelet-Based Bias Potentials

description: Archive with data supporting the paper "Improving the Efficiency of Variationally Enhanced Sampling with Wavelet-Based Bias Potentials" and the related PhD thesis by B. Pampel
DOI: 10.5281/zenodo.5851772
title: Improving the Efficiency of Variationally Enhanced Sampling with Wavelet-Based Bias Potentials

description: Archive with data supporting the paper "Improving the Efficiency of Variationally Enhanced Sampling with Wavelet-Based Bias Potentials" and the related PhD thesis by B. Pampel
DOI: 10.5281/zenodo.7220214
title: Improving the Efficiency of Variationally Enhanced Sampling with Wavelet-Based Bias Potentials

description: Archive with data supporting the paper "Improving the Efficiency of Variationally Enhanced Sampling with Wavelet-Based Bias Potentials" and the related PhD thesis by B. Pampel
DOI: 10.5281/zenodo.2539456
title: Unblinded Data for PLAsTiCC Classification Challenge

description: For classification challenge (https://plasticc.org), the unblinded data files are included here. See PDF note above for more information. The original challenge (Sep 28, 2018 - Dec 17, 2018) was hosted at  https://www.kaggle.com/c/PLAsTiCC-2018 .
description: Funding provided by: US National Science Foundation (NSF), US Department of Energy (DOE),  Association of Universities for Research in Astronomy (AURA), Stanford Linear Accelerator Center (SLAC), LSST Corporation (LSSTc), LSST Dark Energy Science Collaboration (LSST-DESC), LSST Transients and Variables Stars Science Collaboration (LSST-TVS), Kaggle.
description: {"references": ["PLASTICC Team, \"The PLASTICC Data Set,\" https://arxiv.org/abs/1810.00001"]}
DOI: 10.5519/qd.7fkyizrr
title: Query on the Natural History Museum Data Portal (data.nhm.ac.uk) (3628 records)
DOI: 10.5281/zenodo.7272016
title: Dataset for ML model

description: File with data
DOI: 10.5281/zenodo.7272015
title: Dataset for ML model

description: File with data
DOI: 10.3886/6yk2-hg71
title: Mali Compact - Alatona Irrigation: Interim Data Set
DOI: 10.3886/62cc-dg28
title: Mali Compact - Alatona Irrigation: Interim Data Set
DOI: 10.6084/m9.figshare.19787626
title: Supplemental File 1: PLCE1 in Aortic Aneurysm and Dissection

description: Source Data
DOI: 10.3886/h3fb-1921
title: Morocco Employability and Land Compact - Secondary Education: Design Report
DOI: 10.5517/ccdc.csd.cc2c1bh8
title: CCDC 2176029: Experimental Crystal Structure Determination

description: Related Article: Moritz Kofen, Vanessa Braun, Simon M. J. Endraß, Thomas M. Klapötke, Jörg Stierstorfer|2022|Inorg.Chem.|61|17212|doi:10.1021/acs.inorgchem.2c02805
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2c1bj9
title: CCDC 2176030: Experimental Crystal Structure Determination

description: Related Article: Moritz Kofen, Vanessa Braun, Simon M. J. Endraß, Thomas M. Klapötke, Jörg Stierstorfer|2022|Inorg.Chem.|61|17212|doi:10.1021/acs.inorgchem.2c02805
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2c1bkb
title: CCDC 2176031: Experimental Crystal Structure Determination

description: Related Article: Moritz Kofen, Vanessa Braun, Simon M. J. Endraß, Thomas M. Klapötke, Jörg Stierstorfer|2022|Inorg.Chem.|61|17212|doi:10.1021/acs.inorgchem.2c02805
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2c1blc
title: CCDC 2176032: Experimental Crystal Structure Determination

description: Related Article: Moritz Kofen, Vanessa Braun, Simon M. J. Endraß, Thomas M. Klapötke, Jörg Stierstorfer|2022|Inorg.Chem.|61|17212|doi:10.1021/acs.inorgchem.2c02805
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2c1bmd
title: CCDC 2176033: Experimental Crystal Structure Determination

description: Related Article: Moritz Kofen, Vanessa Braun, Simon M. J. Endraß, Thomas M. Klapötke, Jörg Stierstorfer|2022|Inorg.Chem.|61|17212|doi:10.1021/acs.inorgchem.2c02805
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2c1bnf
title: CCDC 2176034: Experimental Crystal Structure Determination

description: Related Article: Moritz Kofen, Vanessa Braun, Simon M. J. Endraß, Thomas M. Klapötke, Jörg Stierstorfer|2022|Inorg.Chem.|61|17212|doi:10.1021/acs.inorgchem.2c02805
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2c1bpg
title: CCDC 2176035: Experimental Crystal Structure Determination

description: Related Article: Moritz Kofen, Vanessa Braun, Simon M. J. Endraß, Thomas M. Klapötke, Jörg Stierstorfer|2022|Inorg.Chem.|61|17212|doi:10.1021/acs.inorgchem.2c02805
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2c1bqh
title: CCDC 2176036: Experimental Crystal Structure Determination

description: Related Article: Moritz Kofen, Vanessa Braun, Simon M. J. Endraß, Thomas M. Klapötke, Jörg Stierstorfer|2022|Inorg.Chem.|61|17212|doi:10.1021/acs.inorgchem.2c02805
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2c63qf
title: CCDC 2180624: Experimental Crystal Structure Determination

description: Related Article: Nikita A. Shekhovtsov, Elena B. Nikolaenkova, Alexey S. Berezin, Victor F. Plyusnin, Katerina A. Vinogradova, Dmitry Yu. Naumov, Natalia V. Pervukhina, Alexsei Ya. Tikhonov, Mark B. Bushuev|2022|Dalton Trans.|51|15166|doi:10.1039/D2DT02460H
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2c6d55
title: CCDC 2180886: Experimental Crystal Structure Determination

description: Related Article: María Diz, María L. Durán-Carril, Jesús Castro, Samuel Alvo, Lucía Bada, Dolores Viña, José A. García-Vázquez|2022|J.Inorg.Biochem.|236|111975|doi:10.1016/j.jinorgbio.2022.111975
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2c6d66
title: CCDC 2180887: Experimental Crystal Structure Determination

description: Related Article: María Diz, María L. Durán-Carril, Jesús Castro, Samuel Alvo, Lucía Bada, Dolores Viña, José A. García-Vázquez|2022|J.Inorg.Biochem.|236|111975|doi:10.1016/j.jinorgbio.2022.111975
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2c6d77
title: CCDC 2180888: Experimental Crystal Structure Determination

description: Related Article: María Diz, María L. Durán-Carril, Jesús Castro, Samuel Alvo, Lucía Bada, Dolores Viña, José A. García-Vázquez|2022|J.Inorg.Biochem.|236|111975|doi:10.1016/j.jinorgbio.2022.111975
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2c6d88
title: CCDC 2180889: Experimental Crystal Structure Determination

description: Related Article: María Diz, María L. Durán-Carril, Jesús Castro, Samuel Alvo, Lucía Bada, Dolores Viña, José A. García-Vázquez|2022|J.Inorg.Biochem.|236|111975|doi:10.1016/j.jinorgbio.2022.111975
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5281/zenodo.7271302
title: List of validated primers of gilthead sea bream (Sparus aurata) and European seabass (DIcentrarchus labrax) developed in PerformFISH project (D2.3)

description: The document contains all the primers identified for the screening of genes tested for their potential as biomarkers to predict quality performance in gilthead sea bream and European sea bass larvae and juveniles in the context of PERFORMFISH (WP2). The spreadsheet has the following information: Pathway, phisiologic process in which the gene is involved; name of protein that gene produces; gene code; acession nº, code given in the consulted databases and the sequence extracted for primer design; FW and RV primer, forward and reverse primer sequence specific for target gene; melt temperature, optimized temperature that primers work at ; amplicon size, size in base pairs of the product produced with the primers; eff%, efficency of primers; r2; source, the origin of the primers, "in house" or "literature" (including available DOI. Each pair of primers are classified using a "traffic light" system indicating their validation status.
DOI: 10.5281/zenodo.7271303
title: List of validated primers of gilthead sea bream (Sparus aurata) and European seabass (DIcentrarchus labrax) developed in PerformFISH project (D2.3)

description: The document contains all the primers identified for the screening of genes tested for their potential as biomarkers to predict quality performance in gilthead sea bream and European sea bass larvae and juveniles in the context of PERFORMFISH (WP2). The spreadsheet has the following information: Pathway, phisiologic process in which the gene is involved; name of protein that gene produces; gene code; acession nº, code given in the consulted databases and the sequence extracted for primer design; FW and RV primer, forward and reverse primer sequence specific for target gene; melt temperature, optimized temperature that primers work at ; amplicon size, size in base pairs of the product produced with the primers; eff%, efficency of primers; r2; source, the origin of the primers, "in house" or "literature" (including available DOI. Each pair of primers are classified using a "traffic light" system indicating their validation status.
DOI: 10.6084/m9.figshare.21453588
title: M2 internal tides from non-repeat altimetry missions

description: M2 internal tides are observed using the sea surface height (SSH) data collected by non-repeat satellite altimetry missions from 2011 to 2017. For comparison, previous internal tide models are mapped from exact-repeat altimetry missions. The three models are constructed using different fitting windows: 40 km, 80 km, and 160 km.
DOI: 10.6084/m9.figshare.21444357
title: Dormoy al - suppl Table 1.pdf

description: Prospective studies have demonstrated the efficacy of osilodrostat in Cushing's disease. No study has evaluated osilodrostat in a series of patients with paraneoplastic Cushing’s syndrome/ectopic ACTH syndrome (PNCS/EAS). Objective: Evaluate in France the real-world efficacy and safety of osilodrostat in PNCS/EAS. Patients: 33 patients with PNCS/EAS with intense/severe hypercortisolism.
DOI: 10.6084/m9.figshare.21444357.v1
title: Dormoy al - suppl Table 1.pdf

description: Prospective studies have demonstrated the efficacy of osilodrostat in Cushing's disease. No study has evaluated osilodrostat in a series of patients with paraneoplastic Cushing’s syndrome/ectopic ACTH syndrome (PNCS/EAS). Objective: Evaluate in France the real-world efficacy and safety of osilodrostat in PNCS/EAS. Patients: 33 patients with PNCS/EAS with intense/severe hypercortisolism.
DOI: 10.5281/zenodo.7271691
title: Arabidopsis HapMap screen for salt-induced changes in root architecture and root:shoot ratio - images BA4 experiment

description: Images of scanned agar plates collected for Arabidopsis accessions exposed to salt stress / control treatment. The data were collected during PhD of Magdalena Julkowska at University of Amsterdam, under supervision of Dr. Christa Testerink.
DOI: 10.5281/zenodo.7271692
title: Arabidopsis HapMap screen for salt-induced changes in root architecture and root:shoot ratio - images BA4 experiment

description: Images of scanned agar plates collected for Arabidopsis accessions exposed to salt stress / control treatment. The data were collected during PhD of Magdalena Julkowska at University of Amsterdam, under supervision of Dr. Christa Testerink.
DOI: 10.5281/zenodo.7271841
title: Arabidopsis HapMap screen for salt-induced changes in root architecture and root:shoot ratio - images BA4 experiment

description: Images of scanned agar plates collected for Arabidopsis accessions exposed to salt stress / control treatment. The data were collected during PhD of Magdalena Julkowska at University of Amsterdam, under supervision of Dr. Christa Testerink.