cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.14457/cu.the.2015.55
title: OCCUPATIONAL NOISE-EXPOSURE AND ASSESSING HEARING LOSS OF NIGHTCLUB WORKERS IN TARAKAN CITY, INDONESIA

description: Occupational noise-exposure is a majority problem in the workplace. Nightclub is one sector of the entertainment industry that will grow rapidly in the future. Many overseas research indicates that nightclub workers were exposed to loud music constantly throughout the work shift and putting their hearing at risk. This study design was cross-sectional with proportional random sampling and it was determined by the number of subjects in each nightclub. A total 117 nightclub workers from 5 nightclub were participated. Noise exposure level was assessed by Sound Level Meter monitoring, measuring hearing loss was done by Audiometer, and other variables (such as: age, gender, educational background, job description, hobby, smoke, drink alcohol, sport activities, duration work, length workday, knowledge and practice, characteristic workers, distance, number of loudspeaker, and total floor area) were assessed by questionnaires and observation. The average noise at nightclub was 107.22 dBA where every employee works more than 6 hours per day. A total of 104 respondents (88.9%) had hearing loss, while 13 respondents (11.1%) did not experience any hearing loss (normal). From 104 respondents who indicated experiencing hearing loss, mostly at the level of mild (88 respondents), 15 respondents (moderate), and 1 (one) respondent in the level of severe. Multiple logistic regression found hobby, smoke, knowledge and practice were strongest predictor may affect to hearing loss. Provide regular inspections of the ears of workers, doing the job rotation system it was a good solution to prevent from hearing loss for management of nightclub. The government also should regularly conduct campaigns and provide training on occupational health, and routinely perform noise measurements.
DOI: 10.14457/cu.the.2015.56
title: THE EFFECT OF CASE-BASED CULTURAL COMPETENT NURSE CARE INTERVENTION FOR PROMOTING CULTURAL COMPETENCY AMONG NURSES AT PRIVATE HOSPITAL IN BANGKOK

description: Cultural competency is particularly important in healthcare industry nowadays, where cultural beliefs have a significant impact on care access, treatment choices, effectiveness of nursing care, and other aspects of patient care. The main purpose of this quasi-experimental study was to evaluate the multi-cultural competency in nurses and to investigate the effect of the care case-based intervention package (12-weekly training and 2-monthly boosters) on the multi-cultural competency in nurses from two medium-size private hospitals in Bangkok, Thailand with similarity in therapeutic specialties and other characteristics in three categories: multi-cultural knowledge, attitude towards different cultures and cultural practice in nurses. The samples were selected using proportional simple random sampling (SRS) method. The sample included 166 nurses (83 nurses from each hospital): Mongkutwattana hospital as control group and Navamin 9 hospital as intervention group. The data was collected using a validated, piloted and reliable self-administered questionnaire and analyzed in SPSS 16.0 using descriptive statistics, regression, t-test, Chi-square and repeated measures using ANOVA and ANCOVA analyses. The analysis showed that the overall level of cultural competency of nurses was classified as low to moderate (75.9% of all nurses scored low multi-cultural knowledge competency while 63.3% and 71.7% of all nurses scored moderate attitude towards different cultures and cultural practice respectively). Further, the 12-weekly training alone resulted in a significantly improved multi-cultural knowledge competency level (P&lt;0.01). However, the knowledge competency level had been found to drop after the training had stopped even 2-monthly boosters were given (P&gt;0.05 as compared to pre-test level). The attitude competency and the nursing practice competency levels were not affected by the intervention package at all (P&gt;0.05). The study has concluded that the good quality of cultural practice was primarily driven by the positive confidence and attitude while the experience factors, level of knowledge and other background marginally affected the quality of cultural practice. Also, the intervention has been found to have significant impact on the improvement of multi-cultural knowledge competency. However, longer-term study may be required in order to effectively study the effect of the intervention on the cultural competency in nurses in a longer-term, especially, on the attitude and nursing practice competency.
DOI: 10.14457/cu.the.2015.57
title: Molecular analysis of Pfmdr1 gene in Plasmodium falciparum in Thai-Cambodia border

description: Drug resistant Plasmodium falciparum is a major problem for malaria control. Policy makers currently depend on in vivo and in vitro tests to adjust antimalarial regimens for malarial treatment guideline. These two methods are required expertise for interpretation and time consuming. Therefore the alternative reliable molecular markers of antimalarial resistance could play an important role in the surveillance of drug efficacy. Pfmdr1 gene has been shown to be a reliable marker of resistance for P. falciparum related to artesunate and mefloquine combination therapies. The propose of this study are to investigated the prevalence of P. falciparum multidrug resistance by determined Pfmdr1 point mutations at codon N86Y, Y184F, S1034C by PCR-RFLP and investigated Pfmdr1 copy number by using real-time quantitative PCR with TaqMan and compared to efficacy of ACTs (Artemisinine Combination Therapies). Seventy-three infected blood samples were collected from the therapeutic efficacy of ACTs project tested in 2 provinces in malaria endemic areas of Thailand which are Chantaburi and Trat. The results showed that in Trat province exhibited the higher percentage of P. falciparum with three or more copies of Pfmdr1 than in Chantaburi (9.09% and 0%, respectively). The mean of Pfmdr1 copy number in P. falciparum collected from Trat and Chantaburi provinces were 2.2 and 1.5 respectively. In contrast, there were no mutations in Pfmdr1 gene in P. falciparum from Trat whereas in Chantaburi found point mutations in N86Y (20%, n=15), S1034C (28.57%, n=7) and no mutations were found in Y184F both in P. falciparum collected from Trat and Chantaburi. These results were correlated to the ACTs efficacy tests. Pfmdr1 mutations and copy number may be used as a high throughput tool to investigate the role of drug resistance of malaria parasites in laboratory studies or large scale epidemiological surveys.
DOI: 10.14457/cu.the.2015.58
title: FACTORS INFLUENCING SEX BEHAVIOURS AMONG YOUTH MYANMAR MIGRANT WORKERS IN SAMUT SAKHON THAILAND

description: The objective of the study is to identify the factors influencing sex behaviors among the youth (18-24 years) Myanmar migrant workers in Samut Sakhon, Thailand. This research study was a cross-sectional survey and purposive sampling, convenient sampling and chain referral sampling (snowball sampling technique) were used to select the 362 youth Myanmar migrant worker participants. Data were collected by using constructed questionnaires with face to face interview and analyzed by descriptive, univariate and multivariate analysis (logistic regression) model is used at significant level of 0.05. The main result of dependent variable revealed that ever have sexual intercourse in migrant workers was 56.6% and abstinences was 43.4%. For early age of first sex, 3.6% have early sex exposure on 15 to 18 years and the respondents with multiple sexual partners were 13.6%. Out of ever have sexual intercourse, protective sex in migrant workers was 14.4% by using condom always for every sexual intercourse and non-protective sex was 85.85%. In inferential analysis, the results showed that married person in marital status was strongly association with ever have sexual intercourse, multiple sex partner and protective sex (p&lt;0.001). Moreover, alcohol drinking was also strongly association with ever have sex and multiple sex partner (p&lt; 0.001). Middle level of knowledge on STI, HIV/AIDS was association with ever have of sex (p 0.017). Therefore this study can be conclude that offer more health education to migrant workers to correct knowledge gaps and misconceptions on STI, HIV/AIDS, early age of sexual intercourse, multiple sex and condom use.
DOI: 10.14457/cu.the.2015.59
title: Developing a policy of informed consent for biobanking in tropical disease research projects, using Delphi technique : principles for good practice

description: The policy of informed consent for biobanking were developed for a standardize guidelines in biobanking. This study is divided into two major phases, the first objective to explore the attitudes and understanding of clinical trial participants to biobanking, subsequently using these results to identify and develop a content of inform consent of biobanking as a policy to improve the quality and standardize for affiliates of Mahidol-Oxford Tropical Medicine Research Unit (MORU); Bangkok in Thailand. The instrument is oriented toward clinical participant attitude, understanding and agreement of experts to determine the policy for future study related to informed consent of biobanking. Phase one using qualitative research methodology, clinical trial participants (N=24) who were already enrolled to clinical research studies at the Hospital for Tropical Diseases were given an information sheet explaining biobanking. An in-depth interview was then conducted along with a demographic questionnaire. The results were analyzed using NVIVO 10 software. From the results, fifty four percent felt they had a clearer understanding of biobanking after reading the brochure. All the respondents were willing to donate a blood sample to a biobank. In conclusions, this study suggests that researchers should provide both written and oral information during enrollment for biobanking studies, giving time for participants to better understand the purpose of biobanking studies prior to signing a consent form. Phase two, four round Policy Delphi techniques was conducted using participants who are expert in clinical trial, policy maker position and currently working in clinical research, based in network of Mahidol-Oxford Tropical Medicine Research Unit (N=30). The master policy narratives was derived through these consensus results. Thematic content analysis was used to analyze the data by using NVIVO 10 software in round one. Descriptive statistics were used to evaluate levels of agreement, including the mean, the percentage of agreement, and the interquartile deviation (IQD) in round two. The percentage of response rate were used in the analytical process in round three and round four. From the results, policy of informed consent for biobanking in Tropical disease research project were developed along with designing of consent form and patient information sheet for biobanking study. The tools will reduce the burden placed on research staff responsible for the generic projects and biobank, at the same time, maximize the protection of clinical trial participants and for principle for good practice in affiliates of MORU in Thailand.
DOI: 10.14457/cu.the.2015.60
title: EFFECTIVENESS OF BEHAVIOR CHANGE INTERVENTION ON INJECTING DRUG USERS

description: The Triple-S intervention was designed grounded in in Social Cognitive Learning Theory and Transtheoritical Model. The intervention focuses on enhancing participants’ motivation to adopt safer behavior and reduce their drug use through a process of observation, positive reinforcement, practicing, and sustaining behavior change. The quasi experimental study aimed to examine the effectiveness of the Triple-S intervention that implemented with Injecting Drug User (IDU) in terms of level of drug injection i.e. rate of drug injection and OTI scale score, drug injection behaviors i.e. polydrug injection, drug mixing, injection at groin and injection site rotation, and harm reduction self-efficacy in three high risk conditions; withdrawal, negative emotions and social pressure conditions. The assessments were conducted four times; baseline, 1-, 3- and 6-month. Ninety participants were assigned to the Triple-S intervention (n=45) and the control group (n=45). Differences between groups were tested by using Chi-square, Independent t-test and Repeated Measured ANOVA. Findings suggested that the Triple-S intervention could significantly reduce the rate of drug injection compare to the control group (p-value&lt;0.001). Unsafe drug injection behaviors were decreased in term of polydrug injection (p-value&lt;0.01) and drug mixing (p-value&lt;0.01). Participants in the Triple-S intervention group reported significantly higher harm reduction self-efficacy in all three high risk conditions at 3- and 6-month follow up. The results of this study may be taken to suggest the importance of behavior change intervention implemented with IDU. It can be applied to cover other harm reduction behaviors, integrated with existing services for IDU and implementation in different context.
DOI: 10.14457/cu.the.2015.61
title: IN THE NAME OF CREATING DRUG FREE SOCIETY : A QUALITATIVE INVESTIGATION ON IMPLICATIONS OF DRUG LAW ENFORCEMENT ON HARM REDUCTION PROGRAMS AND PEOPLE WHO INJECT DRUGS IN KATHMANDU VALLEY NEPAL

description: Polar approaches to the issue of drug use endure in Nepal, where Ministry of Home Affairs (MoHA) enforces criminal drug law to create a drug free society, while Ministry of Health and Population (MoHP) advocates and endorses harm reduction policies to reduce drug-related harms and HIV epidemics.This study employs qualitative methods to explore the implications of drug law enforcement on barriers to accessing harm reduction services, human rights violations and risky behavior among PWID. In June 2016, 28 in-depth interviews were conducted with four distinct population categories [Policy level (1), national HIV program level (7), harm reduction service delivery level (5) and community level (15 (Male -11/Female -4))]. A maximum variance sampling technique was applied. Drug law provided ultimate power to law enforcement authorities and concomitant fear to PWID. Abuse of such power resulted in range of human rights violations, including sexual harassment, brutal torture and financial hassle practiced by nexus of some field authorities and drug rehabs, and increased barriers to accessing harm reduction services as well as increased risky behavior practices among PWID. Law enforcement implicated high drug price, which was associated with delinquent activities and risky behavior. Findings suggested most of the law enforcement related impediments were occurring due to lack of awareness and failure in flow of information within government agencies and law enforcement authorities. Knowledge of harm reduction services resulted in changes in law enforcement activities such as referrals and service intake inside custody.Consistent coordination, monitoring mechanisms and education for law enforcement authorities should be initiated as an immediate response to improve the dire situation of PWID. But the long-term health development of PWID cannot be envisaged without favorable policy and law reform around age of consent, police academy curricula and drug control law through the perspective of public health, human rights and evidence-based harm reduction approaches ensuring a participatory process.
DOI: 10.14457/cu.the.2015.62
title: Comparative effects of high branched-chain amino acid drink, cow milk, or sports drink on performance in male football players

description: การศึกษานี้เป็นการเปรียบเทียบผลของการดื่มเครื่องดื่มที่มีกรดอะมิโนโซ่กิ่งสูง นมวัว หรือเครื่องดื่มเกลือแร่สำหรับนักกีฬา ต่อสมรรถภาพการเล่นกีฬาในนักฟุตบอลชายจำนวน 49 คน อายุ 16-18 ปี ของทีมโรงเรียนมัธยมในจังหวัดระยองจำนวน 4 ทีม ซึ่งการศึกษานี้เป็นการศึกษาแบบ single-blinded crossover trial โดยนักกีฬาจะถูกแบ่งออกเป็น 3 กลุ่ม ได้แก่ 1) เครื่องดื่มเกลือแร่สำหรับนักกีฬา (140 กิโลแคลอรี่ ; คาร์โบไฮเดรต 34.0 กรัม ; ไขมัน 0.001 กรัม) 2) นมวัว (170 กิโลแคลอรี่ ; คาร์โบไฮเดรต 9.0 กรัม ; โปรตีน 10.0 กรัม โดยมี กรดอะมิโนโซ่กิ่ง 1.5 กรัม; ไขมัน 10.0 กรัม) และ 3) เครื่องดื่มที่มีกรดอะมิโนโซ่กิ่งสูง (170 กิโลแคลอรี่ ; คาร์โบไฮเดรต 25.9 กรัม; โปรตีน 10.8 กรัม โดยมีกรดอะมิโนโซ่กิ่ง 4.5 กรัม; ไขมัน 2.8 กรัมt) ในปริมาตร 250 มล. โดยนักกีฬาผู้เข้าร่วมจะได้รับเครื่องดื่มหลังสิ้นสุดการซ้อมทุกวันเป็นเวลา 10 วันสำหรับแต่ละกลุ่ม โดยจะมีช่วงพัก 1 สัปดาห์ก่อนจะเปลี่ยนกลุ่ม ก่อนที่จะได้รับเครื่องดื่มแต่ละชนิดนักกีฬาทุกคนจะต้องได้รับการประเมินปริมาณไขมันในร่างกาย ความอ่อนตัว ความทนทานของกล้ามเนื้อ กำลังกล้ามเนื้อ ความเร็ว และการบาดเจ็บ ในระหว่างที่ได้รับเครื่องดื่มนักกีฬาผู้เข้าร่วมวิจัยจะได้รับแบบบันทึกการรับประทานอาหาร (3-day food record) อีกด้วย และจะประเมินอีกครั้งเมื่อครบระยะเวลาการศึกษาของแต่ละกลุ่มเครื่องดื่ม จากผลการศึกษาพบว่าปริมาณไขมันใต้ผิวหนังเพิ่มขึ้นในกลุ่มเครื่องดื่มที่มีกรดอะมิโนโซ่กิ่ง 0.36±1.38% เมื่อเทียบกับกลุ่มนมวัว 0.15±0.85% ในขณะที่กลุ่มเครื่องดื่มเกลือแร่สำหรับนักกีฬามีปริมาณไขมันใต้ผิวหนังลดลง 0.35±0.92% นอกจากนี้ยังพบว่ากลุ่มนมวัวและกลุ่มเครื่องดื่มที่มีกรดอะมิโนโซ่กิ่งสูงมีความมีความอ่อนตัวของกล้ามเนื้อเพิ่มขึ้น 0.88±2.00 ซม. และ 0.04±2.49 ซม. ตามลำดับ แต่ลดลงในกลุ่มเครื่องดื่มเกลือแร่สำหรับนักกีฬา 0.14±1.98 ซม. ในการทดสอบความทนทานของกล้ามเนื้อโดยการวิดพื้นพบว่าในกลุ่มเครื่องดื่มเกลือแร่สำหรับนักกีฬาและกลุ่มเครื่องดื่มที่มีกรดอะมิโนโซ่กิ่งสูงเพิ่มขึ้น 3.76±8.50 ครั้ง และ 0.33±9.10 ครั้ง ตามลำดับ แต่ลดลงในกลุ่มนมวัว 0.47±4.34 ครั้ง นอกจากนั้นเครื่องดื่มทั้งสามชนิดไม่มีผลต่อกำลังกล้ามเนื้อ (p &gt; 0.05) การทดสอบความเร็วในนักกีฬาพบความแตกต่างอย่างมีนัยสำคัญทางสถิติที่ระยะ 5 ม. 10ม. และ 20 ม.ดังจะเห็นได้จากกลุ่มเครื่องดื่มเกลือแร่สำหรับนักกีฬามีความเร็วลดลงที่ระยะ 5 ม.0.13±0.26 วินาที ที่ระยะ 10 ม. 0.11±0.22 วินาที และที่ระยะ 20 ม. 0.15±0.23 วินาที เมื่อเทียบกับกลุ่มนมวัวที่ลดลงที่ระยะ 5 ม.0.02±0.11 วินาที ที่ระยะ 10 ม. 0.02±0.14 วินาที และที่ระยะ 20 ม.0.03±0.15วินาที (p&lt;0.05) สำหรับการประเมินการบาดเจ็บพบว่าลดลงในกลุ่มนมวัวเมื่อเปรียบเทียบแบบก่อนและหลัง (p &lt; 0.05) และไม่พบความแตกต่างในกลุ่มเครื่องดื่มที่กรดอะมิโนโซ่กิ่งสูงหรือกลุ่มเครื่องดื่มเกลือแร่สำหรับนักกีฬา บริเวณที่พบการบาดเจ็บคือ สะโพก เข่า และข้อเท้าด้านซ้าย กล่าวโดยสรุปเครื่องดื่มทั้งสามชนิดมีผลต่อสมรรถภาพการเล่นกีฬาในนักฟุตบอลที่แตกต่างกันทั้งในด้านที่เพิ่มสมรรถภาพและลดสมรรถภาพการเล่นกีฬา
DOI: 10.14457/cu.the.2015.63
title: Investigation of total antioxidant status and antioxidant activity in pre-dialysis chronic kidney disease patients

description: Chronic kidney disease (CKD) has still been a worldwide public health problem including Thailand. Oxidative stress is considered as an important pathogenic mechanism in CKD. Evaluating the status of micronutrients that have antioxidant properties along with energy and proteins intake, is extremely important to combat antioxidant deficiencies, minimize oxidative stress, and improve the overall health status. This study aimed to measure and compare oxidative stress, antioxidant markers and their relationships with dietary antioxidant food pattern. This study was a cross-sectional study and was performed in outpatients Metabolic clinic. Thirty-three Thai pre-dialysis CKD outpatients and 13 healthy participants were recruited. All patients and controls completed a food frequency questionnaire. Then, anthropometric measurements, general biochemical and antioxidant lab tests were performed. Malonaldehyde (MDA), Total antioxidant status (TAS), Glutathione peroxidase (GPx), Paraoxonase 1 (PON-1) and dietary antioxidant food pattern score were investigated. The results showed that MDA significantly increased (p = 0.01), and PON-1 significantly decreased among CKD patients and controls (p &lt;0.05). There was a positive correlation between the rich-vitamin C vegetable pattern with plasma GPx. Based on this study indicated that oxidative stress increase and antioxidant enzyme activity decrease in Thai CKD outpatients. Therefore, the assessment of dietary antioxidants was important, as deficiency of these nutrients might influence on the balance of the oxidative stress and antioxidants in CKD patients.
DOI: 10.14457/cu.the.2015.64
title: KNEE BIOMECHANICS IN OBESE FEMALE DURING LOCOMOTION

description: The obese woman is strongly knee ostroarthritis 'at risk' group. The high BMI is knee ostroarthritis risk factor by biomechanics during locomotion. The purpose of this study were to compare knee biomechanics during walking such as gait tempero-spatial, kinematic, and kinetic (external knee adduction moment) between overweight obesity I, obesity II and normal healthy female subjects, to study the correlation between gait tempero-spatial data, kinetic and kinematic data (external knee adduction moment), and anthropometry and female BMI levels, and to assess the biomechanical effectiveness of the lateral wedge insole among normal, overweight, obesity I and obesity II females when walking. Eighty Thai females aged between 18 to 40 years, participated in this study and categorized into 4 groups such as normal, overweight, obesity I and obesity II by BMI level (WPRO). A cross-over randomized study was designed to investigate each walking velocities such as self selected, constant velocity (1.24 m/s), and Frode velocity of all participants using 3-D Motion Analysis (N = 80). The significant difference was determined using 2-way ANOVA (p = 0.05) and the correlation of anthropometrics, biomechanics parameter and BMI were determined by Pearson correlation test in study 1. In study 2, the significant difference was determined using Repeated-ANOVA (p = 0.05). The results of study 1 indicated that the overweight and obese groups had changed gait biomechanics and increased knee joint load during walking in all type of velocities when compared with normal groups. The dynamic stability of obese group was maintained by wider step width, longer stance phase duration, shorter swing phase and higher double support time. The BMI was significantly correlated with step width, support time, non support time, double support time and peak external knee adduction moment in low level. The results of study 2 indicated that the peak external knee adduction moment was decreased by the effect of walking shoes and walking shoes with lateral wedge insoles in the self selected speed walking condition. However, the peak external knee adduction moment did not change in the obesity II group. Additionally, there was no effect of lateral wedge insoles on knee adduction angular impulse in all groups during walking. In conclusion, the knee adduction moment was higher in overweight, and obese participants that represent the higher knee joint load to be induced joint cartilage damage cause of osteoarthritis. However, the lateral wedge insoles did not provide any knee joint load effect in the obesity II group. For future study, using the orthosis for reduce biomechanical load that cause of joint cartilage may interest to investigate for prevention potential knee joint osteoarthritis in high BMI female person. In addition, using of lateral wedge insole should be concerned to investigate the long term effect and length of time to apply lateral wedge insoles among those of higher BMI levels, such as obesity II individuals.