cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17632/y9s8t5gm2g.1
title: The Effects of Sadness Induction on the Sense of Ownership

description: The data shows the effects of a sadness induction on the Rubber Hand Illusion. Our experiment was composed of three experimental groups. One group saw neutral pictures in the beginning of each trial, one group saw subliminally presented sad pictures and one group saw supraliminally presented sad pictures. Following the picture presentation, the Rubber Hand Illusion task was performed. Before and after the stimulation, the proprioceptive estimation of the left index finger was taken and a questionnaire on the subjective illusion strength (Botvinick & Cohen, 1998) was surveyed after the post-proprioception measurement. We performed the picture task and the rubber hand illusion task 4 times, each time applying a different stroking style. Stroking was carried out either synchronously (SY) or asynchronously (AS) combined with either slow (3cm/s) (SL) or fast (30cm/s) (FA) stroking speed. At the baseline and after each picture task, participants completed the SAM scale (Bradley & Lang, 1994). In the end, demographical information was surveyed, as well as a questionnaire on dissociative symptoms (FDS; Freyberger et al., 1999).
DOI: 10.17632/y9s8t5gm2g.2
title: The Effects of Sadness Induction on the Sense of Ownership

description: The data shows the effects of a sadness induction on the Rubber Hand Illusion. Our experiment was composed of three experimental groups. One group saw neutral pictures in the beginning of each trial, one group saw subliminally presented sad pictures and one group saw supraliminally presented sad pictures. Following the picture presentation, the Rubber Hand Illusion task was performed. Before and after the stimulation, the proprioceptive estimation of the left index finger was taken and a questionnaire on the subjective illusion strength (Botvinick & Cohen, 1998) was surveyed after the post-proprioception measurement. We performed the picture task and the rubber hand illusion task 4 times, each time applying a different stroking style. Stroking was carried out either synchronously (SY) or asynchronously (AS) combined with either slow (3cm/s) (SL) or fast (30cm/s) (FA) stroking speed. At the baseline and after each picture task, participants completed the SAM scale (Bradley & Lang, 1994). In the end, demographical information was surveyed, as well as a questionnaire on dissociative symptoms (FDS; Freyberger et al., 1999).
DOI: 10.17632/dk7f9m4jbc.1
title: Treatment of erythrodermic psoriasis with biologics: A systematic review

description: Supplemental Table 1. Summary of studies where erythrodermic psoriasis was treated with biologics and risk of bias assessment
DOI: 10.17632/ggmdkjxsr7.1
title: eDST ACLS app

description: Aim of the study: In-house cardiac arrest is a common event associated with high morbidity and mortality. Fortunately, an optimal clinical response can improve patient outcomes. Advanced cardiac life support (ACLS) guidelines represent evidence-based management of in-hospital cardiac arrest, but numerous studies show that compliance is suboptimal. We developed an electronic decision support tool and investigated whether the use of the tool improves adherence to ACLS guidelines. Methods: A prospective randomised trial was conducted at Vanderbilt University Medical Center. Unannounced in-situ simulations of in-hospital cardiac arrest were performed in intensive care unit settings over 15 months. Code teams assembled from physicians and nurses on clinical duty at the time of simulation were randomised to either the electronic decision support tool (eDST) or a control group. Simulations were video recorded and graded for adherence to ACLS guidelines. Results: Use of the new tool resulted in an absolute 10% increase in the percentage of correct clinical actions between the control (n=16) and intervention (eDST; n=11; 73% vs 83%; p=0.001). Use of the tool also resulted in a reduction in median number of errors committed per simulation (2 vs 1, p&lt;0.001). Conclusion: In this study, an electronic decision support tool improved team performance as measured by increased adherence to ACLS guidelines and a reduction in errors. Future research should investigate optimal implementation of the eDST into routine clinical practice and observed impact on both process and outcome metrics.
DOI: 10.17632/ggmdkjxsr7.2
title: eDST ACLS app

description: Aim of the study: In-house cardiac arrest is a common event associated with high morbidity and mortality. Fortunately, an optimal clinical response can improve patient outcomes. Advanced cardiac life support (ACLS) guidelines represent evidence-based management of in-hospital cardiac arrest, but numerous studies show that compliance is suboptimal. We developed an electronic decision support tool and investigated whether the use of the tool improves adherence to ACLS guidelines. Methods: A prospective randomised trial was conducted at Vanderbilt University Medical Center. Unannounced in-situ simulations of in-hospital cardiac arrest were performed in intensive care unit settings over 15 months. Code teams assembled from physicians and nurses on clinical duty at the time of simulation were randomised to either the electronic decision support tool (eDST) or a control group. Simulations were video recorded and graded for adherence to ACLS guidelines. Results: Use of the new tool resulted in an absolute 10% increase in the percentage of correct clinical actions between the control (n=16) and intervention (eDST; n=11; 73% vs 83%; p=0.001). Use of the tool also resulted in a reduction in median number of errors committed per simulation (2 vs 1, p&lt;0.001). Conclusion: In this study, an electronic decision support tool improved team performance as measured by increased adherence to ACLS guidelines and a reduction in errors. Future research should investigate optimal implementation of the eDST into routine clinical practice and observed impact on both process and outcome metrics.
DOI: 10.17632/n96f27nypz.1
title: Supplementary Tables for 'Framing atopic dermatitis topical medication application site discomfort as a signal of efficacy improves willingness to continue use'

description: Supplementary Table 1. Demographic Characteristics of 1039 Study Participants Supplementary Table 2. Common Cognitive Biases Affecting Adherence
DOI: 10.5281/zenodo.3731009
title: Raw diffraction data for structure of SARS-CoV-2 main protease with PCM-0102287 (ID: mpro-x0830 / PDB: 5REX)

description: Raw diffraction data for mpro-x0830 / PDB ID 5REX (see: https://www.ebi.ac.uk/pdbe/entry/pdb/5REX) - SARS-CoV-2 main protease in complex with PCM-0102287 (SMILES:ClCC(=O)N1CCN(Cc2cccc3ccccc23)CC1) collected as part of an XChem crystallographic fragment screening campaign on beamline i04-1 at Diamond Light Source. The deposited structure was automatically processed with standard Diamond tools and PanDDA, however the raw data are being made available to allow reanalysis by any interested party. For more details see: https://www.diamond.ac.uk/covid-19/for-scientists/Main-protease-structure-and-XChem.html
DOI: 10.5281/zenodo.3731010
title: Raw diffraction data for structure of SARS-CoV-2 main protease with PCM-0102287 (ID: mpro-x0830 / PDB: 5REX)

description: Raw diffraction data for mpro-x0830 / PDB ID 5REX (see: https://www.ebi.ac.uk/pdbe/entry/pdb/5REX) - SARS-CoV-2 main protease in complex with PCM-0102287 (SMILES:ClCC(=O)N1CCN(Cc2cccc3ccccc23)CC1) collected as part of an XChem crystallographic fragment screening campaign on beamline i04-1 at Diamond Light Source. The deposited structure was automatically processed with standard Diamond tools and PanDDA, however the raw data are being made available to allow reanalysis by any interested party. For more details see: https://www.diamond.ac.uk/covid-19/for-scientists/Main-protease-structure-and-XChem.html
DOI: 10.5281/zenodo.3731245
title: Raw diffraction data for structure of SARS-CoV-2 main protease with Z1400780201 (ID: mpro-x1093 / PDB: 5RF7)

description: Raw diffraction data for mpro-x1093 / PDB ID 5RF7 (see: https://www.ebi.ac.uk/pdbe/entry/pdb/5RF7) - SARS-CoV-2 main protease in complex with Z1400780201 (SMILES:CN1CCN(CC1)C(=O)CC1=CNC2=NC=CC=C12) collected as part of an XChem crystallographic fragment screening campaign on beamline i04-1 at Diamond Light Source. The deposited structure was automatically processed with standard Diamond tools and PanDDA, however the raw data are being made available to allow reanalysis by any interested party. For more details see: https://www.diamond.ac.uk/covid-19/for-scientists/Main-protease-structure-and-XChem.html
DOI: 10.5281/zenodo.3731246
title: Raw diffraction data for structure of SARS-CoV-2 main protease with Z1400780201 (ID: mpro-x1093 / PDB: 5RF7)

description: Raw diffraction data for mpro-x1093 / PDB ID 5RF7 (see: https://www.ebi.ac.uk/pdbe/entry/pdb/5RF7) - SARS-CoV-2 main protease in complex with Z1400780201 (SMILES:CN1CCN(CC1)C(=O)CC1=CNC2=NC=CC=C12) collected as part of an XChem crystallographic fragment screening campaign on beamline i04-1 at Diamond Light Source. The deposited structure was automatically processed with standard Diamond tools and PanDDA, however the raw data are being made available to allow reanalysis by any interested party. For more details see: https://www.diamond.ac.uk/covid-19/for-scientists/Main-protease-structure-and-XChem.html
DOI: 10.5281/zenodo.3730921
title: Raw diffraction data for structure of SARS-CoV-2 main protease with PCM-0102241 (ID: mpro-x0689 / PDB: 5REJ)

description: Raw diffraction data for mpro-x0689 / PDB ID 5REJ (see: https://www.ebi.ac.uk/pdbe/entry/pdb/5REJ) - SARS-CoV-2 main protease in complex with PCM-0102241 (SMILES:ClCC(=O)N1CCN(CC1)S(=O)(=O)c2cccs2) collected as part of an XChem crystallographic fragment screening campaign on beamline i04-1 at Diamond Light Source. The deposited structure was automatically processed with standard Diamond tools and PanDDA, however the raw data are being made available to allow reanalysis by any interested party. For more details see: https://www.diamond.ac.uk/covid-19/for-scientists/Main-protease-structure-and-XChem.html
DOI: 10.5281/zenodo.3731253
title: Additional data for the publication "Rare Earth Elements in oyster shells: provenance discrimination and potential vital effects"

description: Rare Earth Elements (REE) and yttrium measurements from modern (Marennes-Oléron, France) oyster shells collected by LA-ICP-MS. This dataset is used in the publication 'Rare Earth Elements in oyster shells: provenance discrimination and potential vital effects'.
DOI: 10.5281/zenodo.3731254
title: Additional data for the publication "Rare Earth Elements in oyster shells: provenance discrimination and potential vital effects"

description: Rare Earth Elements (REE) and yttrium measurements from modern (Marennes-Oléron, France) oyster shells collected by LA-ICP-MS. This dataset is used in the publication 'Rare Earth Elements in oyster shells: provenance discrimination and potential vital effects'.
DOI: 10.5281/zenodo.3730920
title: Raw diffraction data for structure of SARS-CoV-2 main protease with PCM-0102241 (ID: mpro-x0689 / PDB: 5REJ)

description: Raw diffraction data for mpro-x0689 / PDB ID 5REJ (see: https://www.ebi.ac.uk/pdbe/entry/pdb/5REJ) - SARS-CoV-2 main protease in complex with PCM-0102241 (SMILES:ClCC(=O)N1CCN(CC1)S(=O)(=O)c2cccs2) collected as part of an XChem crystallographic fragment screening campaign on beamline i04-1 at Diamond Light Source. The deposited structure was automatically processed with standard Diamond tools and PanDDA, however the raw data are being made available to allow reanalysis by any interested party. For more details see: https://www.diamond.ac.uk/covid-19/for-scientists/Main-protease-structure-and-XChem.html
DOI: 10.25345/c5dh59
title: MassIVE MSV000085169 - The human diabetes-specific visceral adipose tissue proteome: insights into mechanisms of adipose tissue dysfunction in metabolic disease
title: Introduction: The human adipose tissue proteome associated with type 2 diabetes (DM) is not well described. An understanding of the DM-specific adipose tissue proteome would provide insight into mechanisms underlying the pathogenesis of DM. Methods: We used label-free proteomics analysis to quantify differences between visceral adipose tissue samples from obese women with and without DM. Results: 2640 protein groups were identified and 1965 were subject to statistical analysis. 23 were differently abundant between groups (q &lt; 0.1, moderated t-test, n = 10). Proteins localized to the mitochondria or involved in mitochondrial functions including the TCA cycle and fatty acid metabolism were decreased in abundance in samples from women with DM relative to NDM samples while proteins involved in cytoskeletal function and innate inflammatory signaling pathways were increased. Conclusion: The visceral adipose tissue proteome in DM is characterized by defects in mitochondrial function, TCA metabolism, inflammation and immunity, and cytoskeletal function. Alterations in the levels of specific proteins associated with these pathways provide insight into mechanisms of adipose tissue dysfunction in the context of metabolic disease.
DOI: 10.5281/zenodo.3731260
title: Raw diffraction data for structure of SARS-CoV-2 main protease with Z271004858 (ID: mpro-x1119 / PDB: 5RF8)

description: Raw diffraction data for mpro-x1119 / PDB ID 5RF8 (see: https://www.ebi.ac.uk/pdbe/entry/pdb/5RF8) - SARS-CoV-2 main protease in complex with Z271004858 (SMILES:NC=1C=CC(=CC1)S(=O)(=O)NC=2C=CC=CN2) collected as part of an XChem crystallographic fragment screening campaign on beamline i04-1 at Diamond Light Source. The deposited structure was automatically processed with standard Diamond tools and PanDDA, however the raw data are being made available to allow reanalysis by any interested party. For more details see: https://www.diamond.ac.uk/covid-19/for-scientists/Main-protease-structure-and-XChem.html
DOI: 10.5281/zenodo.3731261
title: Raw diffraction data for structure of SARS-CoV-2 main protease with Z271004858 (ID: mpro-x1119 / PDB: 5RF8)

description: Raw diffraction data for mpro-x1119 / PDB ID 5RF8 (see: https://www.ebi.ac.uk/pdbe/entry/pdb/5RF8) - SARS-CoV-2 main protease in complex with Z271004858 (SMILES:NC=1C=CC(=CC1)S(=O)(=O)NC=2C=CC=CN2) collected as part of an XChem crystallographic fragment screening campaign on beamline i04-1 at Diamond Light Source. The deposited structure was automatically processed with standard Diamond tools and PanDDA, however the raw data are being made available to allow reanalysis by any interested party. For more details see: https://www.diamond.ac.uk/covid-19/for-scientists/Main-protease-structure-and-XChem.html
DOI: 10.5281/zenodo.3731411
title: Raw diffraction data for structure of SARS-CoV-2 main protease with PCM-0102389 (ID: mpro-x1358 / PDB: 5RFL)

description: Raw diffraction data for mpro-x1358 / PDB ID 5RFL (see: https://www.ebi.ac.uk/pdbe/entry/pdb/5RFL) - SARS-CoV-2 main protease in complex with PCM-0102389 (SMILES:Oc1ccccc1NC(=O)C2CCN(CC2)C(=O)CCl) collected as part of an XChem crystallographic fragment screening campaign on beamline i04-1 at Diamond Light Source. The deposited structure was automatically processed with standard Diamond tools and PanDDA, however the raw data are being made available to allow reanalysis by any interested party. For more details see: https://www.diamond.ac.uk/covid-19/for-scientists/Main-protease-structure-and-XChem.html
DOI: 10.5281/zenodo.3731412
title: Raw diffraction data for structure of SARS-CoV-2 main protease with PCM-0102389 (ID: mpro-x1358 / PDB: 5RFL)

description: Raw diffraction data for mpro-x1358 / PDB ID 5RFL (see: https://www.ebi.ac.uk/pdbe/entry/pdb/5RFL) - SARS-CoV-2 main protease in complex with PCM-0102389 (SMILES:Oc1ccccc1NC(=O)C2CCN(CC2)C(=O)CCl) collected as part of an XChem crystallographic fragment screening campaign on beamline i04-1 at Diamond Light Source. The deposited structure was automatically processed with standard Diamond tools and PanDDA, however the raw data are being made available to allow reanalysis by any interested party. For more details see: https://www.diamond.ac.uk/covid-19/for-scientists/Main-protease-structure-and-XChem.html
DOI: 10.5281/zenodo.3731270
title: Raw diffraction data for structure of SARS-CoV-2 main protease with Z217038356 (ID: mpro-x1132 / PDB: 5RF9)

description: Raw diffraction data for mpro-x1132 / PDB ID 5RF9 (see: https://www.ebi.ac.uk/pdbe/entry/pdb/5RF9) - SARS-CoV-2 main protease in complex with Z217038356 (SMILES:CC1CN(CCO1)C(=O)CN2C=CC=N2) collected as part of an XChem crystallographic fragment screening campaign on beamline i04-1 at Diamond Light Source. The deposited structure was automatically processed with standard Diamond tools and PanDDA, however the raw data are being made available to allow reanalysis by any interested party. For more details see: https://www.diamond.ac.uk/covid-19/for-scientists/Main-protease-structure-and-XChem.html
DOI: 10.25345/c58t3d
title: MassIVE MSV000085170 - Prova Thermoactinoamidi Massive 1 da FBMN 3
title: The putative non-ribosomal peptide synthetase (NRPS) gene cluster encoding the biosynthesis of the bioactive cyclohexapeptide thermoactinoamide A was identified in Thermoactinomyces vulgaris DSM 43016. Based on in silico prediction, the biosynthetic operon was shown to contain two trimodular NRPSs, designated as ThdA and ThdB, respectively. Chemical analysis of bacterial crude extract showed the presence of thermoactinoamide A, thereby supporting this biosynthetic hypothesis. Notably, integrating genome mining with LC-HRMS/MS molecular networking-based investigation of the microbial metabolome, we succeeded in the identification of ten structural variants of thermoactinoamide A (B-K). As only one thermoactinoamide operon was found in T. vulgaris, it can be assumed that all thermoactinoamide congeners are assembled by the same multimodular NRPS system. In the light of these findings, we suggest that the thermoactinoamide synthetase is able to create chemical diversity, combining the relaxed substrate selectivity of some adenylation domains with the iterative and/or alternative use of specific modules. In the frame of our screening program to discover antitumor natural products, thermoactinoamide A unveiled to exert a moderate growth-inhibitory effect in BxPC-3 cancer cells in the low micromolar range, while being inactive in PANC-1 and 3AB-OS solid tumour models.
DOI: 10.5281/zenodo.3731269
title: Raw diffraction data for structure of SARS-CoV-2 main protease with Z217038356 (ID: mpro-x1132 / PDB: 5RF9)

description: Raw diffraction data for mpro-x1132 / PDB ID 5RF9 (see: https://www.ebi.ac.uk/pdbe/entry/pdb/5RF9) - SARS-CoV-2 main protease in complex with Z217038356 (SMILES:CC1CN(CCO1)C(=O)CN2C=CC=N2) collected as part of an XChem crystallographic fragment screening campaign on beamline i04-1 at Diamond Light Source. The deposited structure was automatically processed with standard Diamond tools and PanDDA, however the raw data are being made available to allow reanalysis by any interested party. For more details see: https://www.diamond.ac.uk/covid-19/for-scientists/Main-protease-structure-and-XChem.html
DOI: 10.5281/zenodo.3701939
title: Benchmarking algorithms for gene regulatory network inference from single-cell transcriptomic data

description: This repository contains input files from the synthetic, curated, and processed experimental single-cell gene expression datasets used in BEELINE. New in version 3:<br> 1) Ground-truth networks used for analysis of experimental scRNA-seq datasets for mouse and human datasets<br> 2) Changed license to CC BY-NC 4.0 from GPL v3.0 to account for the non-commercial clause for the network data
DOI: 10.5281/zenodo.3731287
title: Raw diffraction data for structure of SARS-CoV-2 main protease with Z2643472210 (ID: mpro-x1187 / PDB: 5RFA)

description: Raw diffraction data for mpro-x1187 / PDB ID 5RFA (see: https://www.ebi.ac.uk/pdbe/entry/pdb/5RFA) - SARS-CoV-2 main protease in complex with Z2643472210 (SMILES:CN1C=CC(=N1)C(=O)NC[C@@H]2CCCO2) collected as part of an XChem crystallographic fragment screening campaign on beamline i04-1 at Diamond Light Source. The deposited structure was automatically processed with standard Diamond tools and PanDDA, however the raw data are being made available to allow reanalysis by any interested party. For more details see: https://www.diamond.ac.uk/covid-19/for-scientists/Main-protease-structure-and-XChem.html
DOI: 10.5281/zenodo.3731288
title: Raw diffraction data for structure of SARS-CoV-2 main protease with Z2643472210 (ID: mpro-x1187 / PDB: 5RFA)

description: Raw diffraction data for mpro-x1187 / PDB ID 5RFA (see: https://www.ebi.ac.uk/pdbe/entry/pdb/5RFA) - SARS-CoV-2 main protease in complex with Z2643472210 (SMILES:CN1C=CC(=N1)C(=O)NC[C@@H]2CCCO2) collected as part of an XChem crystallographic fragment screening campaign on beamline i04-1 at Diamond Light Source. The deposited structure was automatically processed with standard Diamond tools and PanDDA, however the raw data are being made available to allow reanalysis by any interested party. For more details see: https://www.diamond.ac.uk/covid-19/for-scientists/Main-protease-structure-and-XChem.html
DOI: 10.17037/data.00001662
title: Immunisation risk group - liver disease

description: Read codes for chronic liver disease according to PHE Green Book PPV risk group specification, including biliary atresia and oesophageal varices.
DOI: 10.17037/data.00001663
title: Immunisation risk group - chronic respiratory disease without asthma

description: Read codes for chronic respiratory disease (excluding asthma) according to PHE Green Book PPV risk group specification
DOI: 10.17037/data.00001665
title: Immunisation risk group - Diabetes

description: Read codes for diabetes mellitus according to PHE Green Book PPV risk group specification - reversible causes marked with 'reversible'.
DOI: 10.5281/zenodo.3731021
title: Raw diffraction data for structure of SARS-CoV-2 main protease with PCM-0102911 (ID: mpro-x0831 / PDB: 5REY)

description: Raw diffraction data for mpro-x0831 / PDB ID 5REY (see: https://www.ebi.ac.uk/pdbe/entry/pdb/5REY) - SARS-CoV-2 main protease in complex with PCM-0102911 (SMILES:Cc1ccccc1CN2CCCN(CC2)C(=O)CCl) collected as part of an XChem crystallographic fragment screening campaign on beamline i04-1 at Diamond Light Source. The deposited structure was automatically processed with standard Diamond tools and PanDDA, however the raw data are being made available to allow reanalysis by any interested party. For more details see: https://www.diamond.ac.uk/covid-19/for-scientists/Main-protease-structure-and-XChem.html
DOI: 10.5281/zenodo.3731022
title: Raw diffraction data for structure of SARS-CoV-2 main protease with PCM-0102911 (ID: mpro-x0831 / PDB: 5REY)

description: Raw diffraction data for mpro-x0831 / PDB ID 5REY (see: https://www.ebi.ac.uk/pdbe/entry/pdb/5REY) - SARS-CoV-2 main protease in complex with PCM-0102911 (SMILES:Cc1ccccc1CN2CCCN(CC2)C(=O)CCl) collected as part of an XChem crystallographic fragment screening campaign on beamline i04-1 at Diamond Light Source. The deposited structure was automatically processed with standard Diamond tools and PanDDA, however the raw data are being made available to allow reanalysis by any interested party. For more details see: https://www.diamond.ac.uk/covid-19/for-scientists/Main-protease-structure-and-XChem.html
DOI: 10.15468/wz0cof
title: A review of the Neotropical microcaddisfly genus Acostatrichia Mosely, 1939 with description of a new species from Brazil (Trichoptera: Hydroptilidae: Leucotrichiinae)

description: This dataset contains the digitized treatments in Plazi based on the original journal article Santos, Allan Paulo Moreira (2020): A review of the Neotropical microcaddisfly genus Acostatrichia Mosely, 1939 with description of a new species from Brazil (Trichoptera: Hydroptilidae: Leucotrichiinae). Zootaxa 4755 (2): 201-230, DOI: 10.11646/zootaxa.4755.2.1