cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17632/5fw9pfjdc9
title: FACT mediates the depletion of macroH2A1.2 to function in transcriptional regulation

description: The histone variant macroH2A is generally linked to transcriptionally inactive chromatin, but how macroH2A regulates the chromatin structure and functions in transcriptional process remains elusive. This study reveals that while the integration of macroH2A1.2 into nucleosomes does not affect their stability or folding dynamics, it notably hinders the maintenance function of FACT. We show that FACT effectively diminishes the stability of macroH2A1.2-nucleosomes and expedites their depletion subsequent to the initial unfolding process. Furthermore, we identify the residue S139 in macroH2A1.2 as a critical switch to modulate the FACT’s function in nucleosome maintenance. Genome-wide analyses demonstrate that FACT-mediated depletion of macroH2A-nucleosome allows the correct localization of macroH2A, while the S139 mutation reshapes macroH2A distribution and influences the stimulation-induced transcription and cellular response in macrophage. Our findings provide mechanistic insights into the intricate interplay between macroH2A and FACT at the nucleosome level, and elucidate their collective role in transcriptional regulation and immune response of macrophage.
DOI: 10.17632/6t3s88xm2p
title: LINF_260031400

description: SET25
Leishmania infantum (strain JPCM5)
DOI: 10.17632/7632twh9jr
title: Dynamic Distance-Time Conversion Factor

description: Dynamic Distance-Time Conversion Factor: Enhancing Smart Public Service Planning with Real-time Traffic Big Data
DOI: 10.17632/hx7665c2yr
title: International Finance: Introduction to Basic Concepts

description: The document "International Finance" presents a course designed for international trade students, focusing on how global events impact financial strategies and risk coverage. It highlights the importance of understanding the stock market in a global context and developing financial analyses to design proposals in the new world order.

The course aims to equip students with the skills to characterize the international economic environment and conduct financial operations supported by foreign currency, evaluating capital returns. The required prior competencies include knowledge of macroeconomic indicators, financial mathematics fundamentals, and international negotiation relations.

The course methodology centers on developing competencies to assess the international economic environment and perform exchange operations. Evaluation is based on a classroom project with progressive submissions, including presentations and critical analyses.

The document also addresses concepts such as economic, financial, political, cultural, and environmental globalization, and the integration of international markets. It introduces the International Monetary System, which regulates financial and commercial relations between countries, highlighting the importance of national currencies, exchange rates, and international reserves.

It concludes with the importance of the International Monetary Fund (IMF) and other organizations like the WTO, which facilitate international economic cooperation and global economic stability, emphasizing the role of historical agreements such as Bretton Woods and Basel.
DOI: 10.17632/jr4gfhppg5
title: Exploring the Phytochemical, Proximate, Toxicological, Hepatoprotective, and Therapeutic Potential of Aqueous Extract of Hamelia patens Leaves against CCl4-Induced Hepatotoxicity in Male Albino Rats

description: GC-MS analysis (Table 6) identified several compounds, including β-bisabolene and linalool, which contribute to the distinctive aroma of the plant and may have pharmacological properties. The chromatogram (Fig 3.1) visually represents the chemical composition of the plant extract.

The impact of the extract on liver biomarkers (Table 8a) in CCl4-induced hepatotoxic rats demonstrated significant reductions in AST, ALT, ALP, and bilirubin levels, suggesting a hepatoprotective effect. The antioxidant biomarkers (Table 9a) showed increased levels of GSH, SOD, and CAT, indicating improved antioxidant defense mechanisms. The lipid profile (Table 10a) revealed protective effects on TC, TG, HDL, and non-significant changes in LDL.

Hematological parameters (Table 11) exhibited a significant increase in RBC, Hb, and PCV in extract-treated groups compared to the negative control, suggesting potential benefits on blood parameters. Renal biomarkers (Table 15) showed a significant decrease in urea and creatinine levels, indicating a protective effect on kidney function in male animals.
DOI: 10.17632/npck9skpj7
title: LDHU3_13.0510

description: Protein of unknown function - conserved; Leishmania donovani (HU3 strain)
DOI: 10.17632/sj8p4kbm2f
title: Data for: Pyloric stenosis of infancy, hyperacidity and Occam's razor

description: The cause of pyloric stenosis of infancy
DOI: 10.17632/746vt4jjdz
title: Patient characteristics and medical histories

description: Patient characteristics and medical histories of Turner syndrome associated pregnant patients
DOI: 10.17632/7ynyxw2ktw
title: Soil biota legacies of alfalfa production vary with field conditions and among varieties and species

description: Please refer to the Methods section in the paper: Soil biota legacies of alfalfa production vary with field conditions and among varieties and species
DOI: 10.17632/gb37rvxgcb
title: Supplementary tables

description: Supplementary tables
DOI: 10.17632/n7xzp8c9ks
title: Effect of zoledronic acid on the vertebral body bone mineral density after instrumented intervertebral fusion in postmenopausal women with osteoporosis

description: This study evaluated the effect of anti-osteoporosis treatment with intravenous zoledronic acid during the perioperative period, on the adjacent vertebral body bone mineral density (BMD) after spinal fusion surgery in postmenopausal women with osteoporosis. All data were collected retrospectively from patients' medical records using standardized forms, including: demographics (age, BMI, years since menopause); surgical details of levels included (fusion level and cephalad levels); and BMD values. BMD values (g/cm2) were recorded for the overall lumbar spine, for the levels cephalad to the fused segments, and the femoral neck. The group 0 represents the treated group and group 1 represents the untreated group. The table 1 shows the data about the description of demographic and surgery information of treated group and untreated group. Additionally, the table 2 shows the information about cephalad adjacent vertebral and femoral neck BMD value change. The conclusion shows that perioperative zoledronic acid treatment may offer protection against a significant decrease in BMD of cephalad vertebrae after spinal fusion surgery among postmenopausal women with osteoporosis.
DOI: 10.17632/p2svkvtg3x
title: LINF_330031200

description: Flagella-associated protein 91 | FAP91
Leishmania infantum (strain JPCM5)
DOI: 10.17632/r4wmxz7kcc
title: Elastic properties of phlogopite 1M and 2M1 polytypes

description: The present data reports the results of the analysis of the elastic properties of phlogopite KMg3Si3AlO10(OH)2 (Phl), considering the 1M and 2M1 polytypes of the mineral. The results were obtained from ab initio simulations at the DFT/B3LYP-D* level of theory, using the CRYSTAL17 code.

The dataset is organized as follows:
 - the "CIF files" folder contains the structures obtained from the equation of state calculation carried out on the phlogopite polytypes;
 - the "Elastic Moduli" folder contains information about the fourth-rank elastic tensor (in Voigt's notation) of Phl-1M and Phl-2M1. These files can be used as input for the QUANTAS software (https://github.com/gfulian/quantas) to analyse the elastic properties (e.g., bulk modulus, shear modulus, and more) and the seismic wave velocities;
DOI: 10.17632/ydf8k8g4vb
title: Mathematical discussion in a hybrid environment

description: These data were collected in december 2020 in Italian schools, they are connected to the FEM project M@t.abel 2020.
DOI: 10.17632/ywb36s3cyc
title: Emergence and Increased Epidemic Potential of Dengue Variants with the NS5V357E Mutation after Consecutive Years of Transmission

description: We discover the molecular events involved in overwintering and increased disease severity between consecutive dengue virus serotype 2 outbreaks from 2001 to 2003 in Taiwan. The virus evolved from the early-epidemic strain (Ia) to the late-epidemic strains (Ib and II), featuring three amino acid differences. The data for plaque and foci morphology in Figures 1 and 2, is provided.
DOI: 10.17632/7mybcbhzmb
title: NAC Complaints_Sadovnikova_Supplemental Table 1

description: Supplemental Table 1 for Nipple thrush or dermatitis: a retrospective cohort study of nipple-areolar complex conditions and call for coordinated, multidisciplinary care

Differences in nipple-areolar complex (NAC) diagnosis and complaint management between obstetricians-gynecologists (OBGYN) and primary care physicians (PCP). The odds ratios (OR) and 95% confidence intervals (CI) were calculated at the encounter level without adjustment for repeated visits. The referent group is PCP.
DOI: 10.17632/gm37ztb69c
title: Dermoscopic changes in acquired melanocytic nevi during and after pregnancy – A Case-control Prospective Study

description: Our study aimed to examine the most common dermoscopic changes in acquired melanocytic nevi during pregnancy and six months post-partum in two distinct populations—Brazil and Australia—each with very different melanoma risk factors. We compared these changes to those observed in a control group consisting of non-pregnant biological sisters. This control group was selected due to the likelihood of shared genetic and environmental risk factors for melanoma, as evidenced by the similarity of baseline demographics and risk factors between cases and controls.
In addition to dermoscopic examination, we utilized confocal microscopy for suspicious lesions identified through dermoscopy, providing a thorough and multi-faceted analysis of these changes.
DOI: 10.17632/hs7r56rc6j
title: Normative reference value of BESS scale in recreational athletes

description: A cross sectional study was performed on 90 recreational athletes . The balance  was assessed on different surfaces with eyes open and closed using the BESS scale and there normative reference values were found , which came out to be  not normally distributed.
DOI: 10.17632/pxxtzgzgcz
title: Data for: Efficacy of single-shot adductor canal block combined with posterior capsular infiltration on postoperative pain and functional outcome after total knee arthroplasty: a prospective, double-blind, randomized controlled study

description: These data are the original data of two groups of patients in this randomized controlled trial
DOI: 10.17632/rs4phbvhzf
title: Casas Grandes - earthen architectural materials

description: These data confirmed that the soil naturally mixed with powdered caliche was employed for construction of Paquimé, which made it possible to construct massive earthen architecture. In case of Arroyo Seco, soil was obtained from the site where buildings were constructed. The results also indicate the plausibility that the soil was prepared desegregating collapsible surface of the bedrock in the cave, prior to construction of dwellings in Cueva de la Olla.
DOI: 10.17632/s2yx7csmf9
title: LINF_150009700

description: Protein of unknown function - conserved; Leishmania infantum (strain JPCM5)
DOI: 10.17632/tcd68zdf49
title: Proteomics of HTR8 cells with bile acids and EBSS treatment

description:    HTR8 cells maintained in Earle's balanced salt solution (EBSS) and treated with 100 μM chenodeoxycholic acid (CDCA) or 100 μM deoxycholic acid (DCA) for 18 h were subjected to proteomic analysis 
    
After treatment with bile acids (CDCA or DCA) and EBSS, HTR8 cells (two duplicates in each group) were harvested and lysed. The protein lysates of HTR8 cells were digested with trypsin (Promega, Madison, WA, USA). The resulting peptide in each sample was then labeled using a Tandem Mass Tags (TMT) Labeling kit (ThermoFisher Scientific) following the manufacturer’s instructions and fractionated by reverse-phase chromatography using high-performance liquid chromatography (1260 Infinity II; Agilent, USA). Liquid chromatography (LC)-mass spectrometry (MS)/MS analysis was performed on a mass spectrometer (positive ion mode; Q Exactive Plus; ThermoFisher Scientific) coupled with a nanoflow LC system (Easy-nLC; ThermoFisher Scientific). MS data were acquired and processed using MASCOT (version 2.6; Matrix Science, London, UK) embedded into Proteome Discoverer 2.2. Proteins with fold changes higher than 1.2 or less than 0.83 and p values less than 0.05 were considered as differentially expressed.
DOI: 10.17632/yxffvd8tmw
title: Myocardial Patch Data

description: PCR, Rheology, and IF Analysis Data for Myocardial Patch Data
DOI: 10.17632/zxdgbzfs5n
title: Appedix A. Included publications for JCP.

description: Appendix A. Included publications for JCP.
DOI: 10.17632/22rxw96d45
title: Dataset for manuscript "Protective factors against burnout symptoms in Finnish adolescents"

description: The aim of the study was to research possible protective factors against burnout in adolescents. The data is gathered from 284 Finnish upper secondary school students. The indipendent variables used in this study were coping self-efficacy, resilience and school atmosphere. The dependent variable was burnout symptoms. Moreover, we used some demographic variables to see whether they affected the results in any way. The dataset shows the independent and dependent variables as well as the demographic variables used to research this. The results from the study suggest that using problem-focused coping, seeking support from friends and family and a school atmosphere that instills meaning in the school work were associated with less burnout symptoms.
DOI: 10.17632/35b4zxvmkz
title: LDHU3_09.1020

description: AAA+ ATPase; Leishmania donovani (HU3 strain)
DOI: 10.17632/5g7szbf4p2
title: single_cell FEM

description: data for paper "FEM: mining biological meaning from cell level in single-cell RNA sequencing data" The directory hg19 is PBMC scRNA-SEQ data. The directory human_liver is liver scRNA-SEQ data. The directory human_pancreas is pancreas scRNA-SEQ data. The directory gsea_cut_off\hg19 is PBMC FEM data. The directory gsea_cut_off\human_liver is the liver FEM data. The directory gsea_cut_off\human_pancreas is pancreas FEM data.
DOI: 10.17632/8kz7rwmwnt
title: data of the ASD and ND groups

description: The data of each participant provided here include: 1) sex, 2) age, 3) level of saliva nitrite, 4) level of serum nitrite, 5) level of serum nitrate, 6) ABC score, 7) CARS score.
DOI: 10.17632/bpr9dxmg6f
title: LDHU3_07.0760

description: ras-related protein rab-14
Leishmania donovani (HU3 strain)
DOI: 10.17632/g3fb9fbp9g
title: Thermal stability of two xylanases from Macrotermes subhyalinus little soldier: kinetic and thermodynamic analysis | IJB

description: The knowledge on thermal inactivation kinetics of enzymes is necessary to allow their adequate utilization as natural biopreservatives in the food industry and technology applications. In this work, the kinetics of thermal inactivation was studied for the previously purified and characterized xylanases Xyl1 and Xyl2 from Macrotermes subhyalinus little soldier. Samples of xylanases were treated at different time-temperature combinations in the range of 5-60 min at 50-65°C and the kinetic and thermodynamic parameters for xylanases were calculated. The inactivation kinetic follows a first-order reaction with k-values between 0.0192 ± 0.0002 to 0.0405 ± 0.0003 and 0.0119 ± 0.0005 to 0.0418 ± 0.0004 min-1 for Xyl1 and Xyl2, respectively. Activation energy (Ea) and Z-values were estimated to 48.08 ± 1.84 kJ mol-1 and 43.47 ± 3.02°C for Xyl1, 75.52 ± 3.52 kJ.mol-1 and 27.77 ± 1.87°C for Xyl2. The catalytic reactions of both xylanases are endothermic due to positive enthalpy. The high value obtained for the variation in enthalpy of activation indicates that a high amount of energy is required to initiate denaturation, probably due to the molecular conformation of xylanases. All results suggest that both xylanases are relatively resistant to long heat treatments up to 50°C.
DOI: 10.17632/j2jpj3p29f
title: Gel images for Ahuja et al. 2021

description: Southern blot images for Figure 2B, Figure 2E, and Figure S2
DOI: 10.17632/jj52wcb73t
title: Awe and Branding 1

description: Data from the Awe and Branding 1 message experiment.
DOI: 10.17632/smctgsb4wm
title: Stratigraphic Distribution of the Cenozoic Species in the Western High Atlas.

description: The study of Neogene stratigraphic species distribution in the Western High Atlas (WHA) reveals significant environmental and sedimentary variation. Literature data and our stratigraphic sections show a diversity of fauna, notably bivalves, gastropods and benthic foraminifera, essential for dating sediments and interpreting paleoenvironmental conditions. Variations in species abundance and size during the Neogene reflect environmental changes, such as water temperature and salinity. Specific fossils are needed to precisely define the limits of the Pliocene.
DOI: 10.17632/whg3wptwkt
title: LINF_090010900

description: Hypothetical protein - conserved; Leishmania infantum (strain JPCM5)
DOI: 10.17632/2yp66dt99f
title: VOFINDEX1

description: Index of social relevant issues, for use in the VOF.
DOI: 10.17632/54xr9bsxd2
title: Metabolomic data of H460 and A549 cells after trametinib treatment

description: MAP kinse-ERK kinase inhibitor (MEKi) resistance remains unknown. We determined gene expression profiling in MEKi-resistant cells and MEKi-sensitive cells after MEKi treatment using UHPLC-MS/MS.
DOI: 10.17632/576chjw8tp
title: Harmonization of six quantitative SARS-CoV-2 serological assays using sera of vaccinated subjects.

description: Harmonization of six quantitative SARS-CoV-2 serological assays using sera of vaccinated subjects.
Clinica Chimica Acta. Volume 522, November 2021, Pages 144-151
DOI: 10.17632/5w6pr9ps3w
title: MotionFormVIP

description: For plotting figures, download data: "Figure_Souce_Data.mat"; 
For plotting Supplementary figures, download data: "SupFigure_data.mat";

The relevant calculations mentioned in the article can be found in the following files:
"Code_Demo.m": This file contains implementations for AMI , BMI , CI , conditional Fisher information, as well as calculations for linear and nonlinear fitting.
"Model_linear_2D_MF.m": This is a function file related to the linear model fitting in two dimensions.
"Model_nonlinear_2D_MF.m": This file contains functions related to the nonlinear model fitting in two dimensions.
"bimodalgaussfit.m": This is a function file related to fitting bimodal Gaussian distributions.
"cxcorr.m": This file contains functions related to cross-correlation calculations.

The original neuron data is available upon request from the lead contact , as it is too large to be included here.
DOI: 10.17632/87rdb964yc
title: LINF_080014100

description: Dpy-30 motif containing protein; Leishmania infantum
DOI: 10.17632/96bnndpk4b
title: Data for: Effects of a companion plant on the formation of mycorrhizal propagules in Artemisia tridentata seedlings

description: The excel file contains the raw data used in this manuscript, except for the DNA sequences, which will be available on NCBI. The data are in different sheets following the order used in the results section of the manuscript.
DOI: 10.17632/b97n8px4cg
title: Raw data-Progression of whole-heart Atherosclerosis by coronary CT and major adverse cardiovascular events

description: raw data of the research work
DOI: 10.17632/bbrrsxpn5t
title: Effects of kinship and host quality on group reproduction in Sclerodermus cereicollis using a choice test

description: This dataset describes the behaviour and reproductive outcomes of Sclerodermus cereicollis foundresses, focusing on how host size variation and female relatedness affect these dynamics. Foundresses, grouped according to kinship, were given two hosts of different sizes. Key observations included host selection, oviposition timing, movement between hosts and foundress mortality. 
Data are provided for foundress mortality, timing of victim attack and subsequent offspring development from oviposition to emergence, offspring emergence, and foundress movements and positions.
DOI: 10.17632/c6gr36ff98
title: LINF_210013600

description: Closed mitosis protein 1 | CMP1; Leishmania infantum (strain JPCM5)
DOI: 10.17632/jknxdjmm7b
title: A summary of the reported use of JAK inhibitors to treat cutaneous and systemic sarcoidosis.

description: A summary of the reported use of JAK inhibitors to treat cutaneous and systemic sarcoidosis. CR – complete response; NCR – near complete response; PR – partial response.
DOI: 10.17632/jmtpwdb6vv
title: Bicentric lesion of colon cancer with postoperative fever: a case report

description: The information of patient's whole genome sequencing in the report case.
DOI: 10.17632/nj5ck53c36
title: LINF_140013600

description: mitoribosomal protein bL21m Leishmania infantum (strain JPCM5)
DOI: 10.17632/rvn7h96s2f
title: data

description: For a certain part of the data, pictures and tables of this experimental paper
DOI: 10.17632/smf4zc5ysw
title: State transition matrix for a multistate model in a multisite Integrated Population Model

description: The following transition matrix corresponds to the formulation of a multistate model for estimating survival, permanent emigration, and movement probability between three sites. Briefly, we had 37 observed states, denoting three sites (Catalonia, Aragon, or Valencian Community), age (1-year-old, 2-year-old, 3-year-old, and ≥4-year-old), mark status (seen with both wing tag and plastic band, wing tag only, or plastic band only), and recovery of dead individuals. We estimated site-specific probabilities of non-adult (Sna: 1- to 3-year-old) and adult (Sad: ≥4-year-old) true survival, non-adult (Ena) and adult (Ead) permanent emigration from the study area, and non-adult (ψna) and subadult/adult (ψad) movements between sites. A common probability (i.e., without site distinction) for wing tag loss, plastic band loss, and recovery was estimated as the marks were made of the same materials and recoveries were conducted anywhere (inside and outside of the study area). Recapture probabilities were estimated as site-specific without age distinction and using Pradel and Sanz-Aguilar (2012) transition matrix to estimate recapture probabilities for previously and not-previously captured individuals. 

This matrix was used for Chapter 3 of my PhD thesis titled Multisite Integrated Population Model Reveals Contrasting Vital Rates Contributions on Population Dynamics of a Highly Mobile Species. PhD thesis: From Local to Regional: Demographic and Population Dynamics of a Long-lived Scavenger Species in a Changing Environment.
DOI: 10.17632/tfyrfmp4p2
title: Mice learn from predator-attack experience to enhance flight behavior by optimizing environmental exploration strategy

description: 
Successful avoidance of predators is critical for animal survival. However, little is known of how predator-attack experience may affect predator-defense behavior. Here, we caught mice by their tails to simulate a predator attack. We found that this led to a quicker flight response to visual threatening cues in experiences mice compared to naive mice. A single predator attack did not induce anxiety but increased activity in brain nuclei related to innate fear and learning. Predator-attack induced quickening of flight was partly rescued by pharmacological blockade of protein synthesis which is critical for learning. Experienced mice significantly reduced focused exploration of the floor during environmental exploration, which may facilitate the discovery of predators. These results suggest that mice can learn from experience of predator attacks to optimize their behavioral patterns for immediate detection of predator cues and a heightened response to these cues, thereby increasing the probability of survival.