cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.21942/uva.16601411.v1
title: Flow cytometry dataset EDTA vs. citrate for revision 1

description: Flow cytometry data set belonging to the first revision of the manuscript "EDTA stabilizes the concentration of platelet-derived extracellular vesicles during blood collection and handling".
DOI: 10.5517/ccdc.csd.cc25m869
title: CSD 2014510: Experimental Crystal Structure Determination

description: Related Article: Artem Kuznetsov|2021|CSD Communication|||
DOI: 10.6084/m9.figshare.15021040
title: Isolation and characterization of flavonoid compounds from <i>Stachytarpheta jamaicensis</i> (L.) Vahl and its role as anti-gastro ulcerative agent in rats

description: Stomach ulcer is one of the most common gastrointestinal problems in the world. This study aimed to isolate flavonoid compounds from methanol extract of the aerial parts of <i>Stachytarpheta jamaicensis</i> (L.) Vahl. and evaluate its protective and therapeutic effects against gastric ulcer. Chromatographic techniques were used for the identification of the isolated compounds. To explore the effects of the plant extract, it was administrated by oral gavage for one week either before or post-ethanol ulcer induction. Ranitidine was also evaluated as a reference drug. Stomach pH, gastric juice volume, lesions number, glutathione, superoxide dismutase, malondialdehyde, succinate dehydrogenase, lactate dehydrogenase, acid phosphatase, Interleukin-10, intracellular adhesion molecule-1, prostaglandin E2, and total protein levels were estimated in gastric tissue. Stomach histopathological features were also monitored. Six flavonoid compounds were isolated, where five of them were isolated for the first time (vitexin, isovitexin, apigenin 7,4′-dimethyl ether, 5,7,2′-trimethoxyflavone, and scutellarein), while apigenin was previously reported. Treatment with plant extract recorded amelioration in all the biochemical parameters. The methanol extract of plant aerial parts had prophylactic and treatment effects against gastric ulcer in rats, where its treatment effect exceeded its protective role. The extract recorded anti-inflammatory, and antioxidant effects due to the presence of flavonoid compounds.
DOI: 10.6084/m9.figshare.15021040.v1
title: Isolation and characterization of flavonoid compounds from <i>Stachytarpheta jamaicensis</i> (L.) Vahl and its role as anti-gastro ulcerative agent in rats

description: Stomach ulcer is one of the most common gastrointestinal problems in the world. This study aimed to isolate flavonoid compounds from methanol extract of the aerial parts of <i>Stachytarpheta jamaicensis</i> (L.) Vahl. and evaluate its protective and therapeutic effects against gastric ulcer. Chromatographic techniques were used for the identification of the isolated compounds. To explore the effects of the plant extract, it was administrated by oral gavage for one week either before or post-ethanol ulcer induction. Ranitidine was also evaluated as a reference drug. Stomach pH, gastric juice volume, lesions number, glutathione, superoxide dismutase, malondialdehyde, succinate dehydrogenase, lactate dehydrogenase, acid phosphatase, Interleukin-10, intracellular adhesion molecule-1, prostaglandin E2, and total protein levels were estimated in gastric tissue. Stomach histopathological features were also monitored. Six flavonoid compounds were isolated, where five of them were isolated for the first time (vitexin, isovitexin, apigenin 7,4′-dimethyl ether, 5,7,2′-trimethoxyflavone, and scutellarein), while apigenin was previously reported. Treatment with plant extract recorded amelioration in all the biochemical parameters. The methanol extract of plant aerial parts had prophylactic and treatment effects against gastric ulcer in rats, where its treatment effect exceeded its protective role. The extract recorded anti-inflammatory, and antioxidant effects due to the presence of flavonoid compounds.
DOI: 10.6084/m9.figshare.15544073
title: Can treatment response to SGLT2-inhibitors in syndrome of inappropriate antidiuresis be predicted by copeptin, natriuretic peptides and inflammatory markers?

description: The syndrome of inappropriate antidiuresis (SIAD) is the main cause of hyponatremia and the SGLT2-inhibitor empagliflozin is a promising new treatment option. A biomarker predicting treatment response could optimize treatment success. Secondary analysis of a trial including 84 hospitalized patients with SIAD-induced hyponatremia. Patients were randomized to four days of treatment with empagliflozin 25 mg/d (<i>n</i> = 43) or placebo (<i>n</i> = 41) with both groups receiving fluid restriction &lt;1000 ml/d. Baseline levels of copeptin, the natriuretic peptides MR-proANP and NT-proBNP and C-reactive protein (CRP) were evaluated as predictors for treatment response defined as absolute sodium change, using linear regression models. Additionally, urinary sodium was assessed as predictor for non-response to fluid restriction alone by constructing the receiver-operating characteristic (ROC) curve. No clinically relevant predictive value for treatment response to empagliflozin could be found for copeptin, MR-proANP, NT-proBNP or CRP. A urinary sodium cut-off of &gt;76 mmol/l led to a specificity of 91.7% [95% confidence interval (CI): 75%, 100%] and sensitivity of 51.9% [33.3%, 70.4%] to predict non-response to fluid restriction alone. Based on our data, no biomarker could be identified as predictor for treatment response to empagliflozin. Urinary sodium was confirmed as a good marker for non-response to fluid restriction in SIAD patients. <b>Clinical trial registration</b>: ClinicalTrials.gov (Number: NCT02874807)
DOI: 10.6084/m9.figshare.15544073.v2
title: Can treatment response to SGLT2-inhibitors in syndrome of inappropriate antidiuresis be predicted by copeptin, natriuretic peptides and inflammatory markers?

description: The syndrome of inappropriate antidiuresis (SIAD) is the main cause of hyponatremia and the SGLT2-inhibitor empagliflozin is a promising new treatment option. A biomarker predicting treatment response could optimize treatment success. Secondary analysis of a trial including 84 hospitalized patients with SIAD-induced hyponatremia. Patients were randomized to four days of treatment with empagliflozin 25 mg/d (<i>n</i> = 43) or placebo (<i>n</i> = 41) with both groups receiving fluid restriction &lt;1000 ml/d. Baseline levels of copeptin, the natriuretic peptides MR-proANP and NT-proBNP and C-reactive protein (CRP) were evaluated as predictors for treatment response defined as absolute sodium change, using linear regression models. Additionally, urinary sodium was assessed as predictor for non-response to fluid restriction alone by constructing the receiver-operating characteristic (ROC) curve. No clinically relevant predictive value for treatment response to empagliflozin could be found for copeptin, MR-proANP, NT-proBNP or CRP. A urinary sodium cut-off of &gt;76 mmol/l led to a specificity of 91.7% [95% confidence interval (CI): 75%, 100%] and sensitivity of 51.9% [33.3%, 70.4%] to predict non-response to fluid restriction alone. Based on our data, no biomarker could be identified as predictor for treatment response to empagliflozin. Urinary sodium was confirmed as a good marker for non-response to fluid restriction in SIAD patients. <b>Clinical trial registration</b>: ClinicalTrials.gov (Number: NCT02874807)
DOI: 10.6084/m9.figshare.15156357
title: VPP_TEST_DATA

description: Two test systems are uploaded.
DOI: 10.6084/m9.figshare.15156357.v2
title: VPP_TEST_DATA

description: Two test systems are uploaded.
DOI: 10.6084/m9.figshare.15156357.v1
title: VPP_TEST_DATA

description: Two test systems are uploaded.
DOI: 10.3886/e152141
title: How Fertility Behavior Responds to Trade Shock: Evidence from China

description: This paper examines the fertility effect of a trade shock induced by China’s accession to the WTO by exploiting the variation in regional exposure to the shock. We find that trade uncertainty decline restrains fertility by both delaying childbearing and reducing lifetime fertility. Overall, the negative effect is larger in urban areas and for couples that already have children, especially sons. In addition, consistent with Becker’s model, the shock to females decreases fertility, but the shock to males has an opposite impact. Finally, with son preference, higher opportunity cost raises the probability of the first child being a boy.
description: whole population in China.
description: This data contains information on fertility behavior and trade uncertainty in China. We rely on China's 2005 population census to measure the fertility behavior of individuals. We link children to their parents and then trace the fertility history of each woman according to the ages of her children. In addition, we measure the decline in product-level trade uncertainty following Pierce and Schott (2016), which is defined as the gap between NTR tariff rates that are locked in by PNTR and non-NTR rates. We compute the NTR gap using ad valorem equivalent NTR and non-NTR tariff rates in 1999 (the year before the passage of PNTR in the US) provided by Feenstra et al. (2002).
DOI: 10.6084/m9.figshare.16719997
title: SARS-COV-2 INFECTION IN CANCER PATIENTS A population-based study

description: Study population: all the residents in the Veneto Region (northeastern Italy) who were consecutively tested for SARS-CoV-2 infection between February 22nd and July 31st, 2020 and have a cancer diagnosis established within 10 year before viral-testing (34,929 subjects).
DOI: 10.6084/m9.figshare.16640209.v2
title: Supplementary data to publication "Untargeted metabolomics reveals metabolic stress alleviation by prepartum exercise in transition dairy cows"

description: Prepartum exercise is one of the methods of optimizing perinatal management practices to improve health. However, mechanism of prepartum exercise regulates on metabolism are rarely been described. The objective of this study was to investigate metabolic changes in transition cows with exercise. 24 Holstein transition dairy cows were assigned to exercise (n = 12) and control group (n = 12) on approximately d 21 prepartum, plasma was collected during -21, -7, 0, +7, and +30 d relative to calving. The researchers assisted the exercise group cows to walk for a targeted 45 min at 3.25 km/h, 2 times/d. Plasma non-esterified fatty acid (NEFA), β-hydroxybutyric acid (BHBA), glucose, and triglycerides were evaluated, and metabolic profile was analyzed using ultra-high-performance liquid chromatography time-of-flight mass spectrometry. The results demonstrated that concentrations NEFA at -7 d, glucose at 0d, and BHBA at +7d relative to calving were obviously reduced in exercise cows. Untargeted metabolomics analyses showed that cows had experienced severe metabolic stress during calving, including increased fatty acid and glucose metabolism, and reduced bile acid and tryptophan metabolism. Four key metabolites were identified in cows with exercise during metabolic stress: gentisic acid, kynurenine, homovanillic acid, and cis-9-palmitoleic acids. Correlation and pathway analysis indicated that exercise had down-regulation of NEFA and BHBA production and maintained glucose levels through tryptophan-kynurenine metabolism, improving postpartum health.
DOI: 10.7479/mn2v-pm95
title: Dataset: Korn 2021: Revision of <i>Tornoceras typus</i> (Sandberger Sandberger, 1851) – an iconic Devonian ammonoid of a clade with slow morphological evolution

description: Photographs, illustrations and data for Tornoceras typus, Tornoceras vretterense, Tornoceras Tornoceras fundibulum, Domanikoceras martenbergense and Linguatornoceras asbeckense.
DOI: 10.5445/ir/1000138652
title: Digitaler Anhang zur Dissertation "Effiziente Implementierung und Berechnung von NMR-Kopplungskonstanten im Rahmen von nichtrelativistischer und quasirelativistischer Theorie"
DOI: 10.5258/soton/d1994
title: Dataset for Dynamic changes in anaerobic digester metabolic pathways and microbial populations during acclimatisation to increasing ammonium concentrations

description: This file contains the analytical data for the publication: Wei Zhang, Anna M. Alessi, Sonia Heaven, James P.J. Chong, Charles J. Banks (2021) 'Dynamic changes in anaerobic digester metabolic pathways and microbial populations during acclimatisation to increasing ammonium concentrations', Waste Management, Vol. 135, pp 409-419, https://doi.org/10.1016/j.wasman.2021.09.017
DOI: 10.6084/m9.figshare.16778926.v1
title: Hazard Assessment for a Glacier Lake Outburst Flood in the Mo Chu River Basin, Bhutan

description: This dataset represents the mein output of our studies. It shows the flow velocity and flood depth of a GLOF modelled with HEC-RAS 5.0.7.<br>
DOI: 10.6084/m9.figshare.15022521
title: Metadata record for: RNA-seq of peripheral blood mononuclear cells of congenital generalized lipodystrophy type 2 patients

description: This dataset contains key characteristics about the data described in the Data Descriptor RNA-seq of peripheral blood mononuclear cells of congenital generalized lipodystrophy type 2 patients. <br> Contents: <br> 1. human readable metadata summary table in CSV format 2. machine readable metadata file in JSON format
DOI: 10.6084/m9.figshare.15022521.v1
title: Metadata record for: RNA-seq of peripheral blood mononuclear cells of congenital generalized lipodystrophy type 2 patients

description: This dataset contains key characteristics about the data described in the Data Descriptor RNA-seq of peripheral blood mononuclear cells of congenital generalized lipodystrophy type 2 patients. <br> Contents: <br> 1. human readable metadata summary table in CSV format 2. machine readable metadata file in JSON format
DOI: 10.6084/m9.figshare.16778926
title: Hazard Assessment for a Glacier Lake Outburst Flood in the Mo Chu River Basin, Bhutan

description: This dataset represents the main outputs of our studies.It shows the flow velocity and flood depth raster files of a GLOF modelled with HEC-RAS 5.0.7.
DOI: 10.6084/m9.figshare.16778926.v3
title: Hazard Assessment for a Glacier Lake Outburst Flood in the Mo Chu River Basin, Bhutan

description: This dataset represents the main outputs of our studies.It shows the flow velocity and flood depth raster files of a GLOF modelled with HEC-RAS 5.0.7.
DOI: 10.6084/m9.figshare.16778926.v2
title: Hazard Assessment for a Glacier Lake Outburst Flood in the Mo Chu River Basin, Bhutan

description: This dataset represents the main outputs of our studies.It shows the flow velocity and flood depth raster files of a GLOF modelled with HEC-RAS 5.0.7.
DOI: 10.5281/zenodo.5560868
title: Replication Package for: Welfare and Redistribution in Residential Electricity Markets with Solar Power

description: The Stata Do-Files, Matlab Scripts and Functions in this folder can be used to replicate the tables and graphs of the paper "Welfare and Redistribution in Residential Electricity Markets with Solar Power" by Fabian Feger, Nicola Pavanini, and Doina Radulescu.
DOI: 10.5281/zenodo.5560881
title: Fully amorphous atactic and isotactic block copolymers and their self-assembly into nano- and microscopic vesicles

description: Data underlying the figures in the publication “Fully amorphous atactic and isotactic block copolymers and their self-assembly into nano- and microscopic vesicles”, published in <em>Polym. Chem., </em><em><strong>2021</strong></em><em>, 12, 5377-5389</em>. https://pubs.rsc.org/en/content/articlelanding/2021/PY/D1PY00952D Table of contents: <strong>1. Figure 1</strong>: Zip archive containing the experimental data (NMR spectra) for the kinetics of the PBO syntheses (<em>Figure 1c</em>) and the PBO-b-PEEGE syntheses (<em>Figure 1d</em>). <strong>2. Figure 2</strong>: Zip archive containing the experimental data for <em>Figure 2</em>. Structural characterisation of the (S)-BCP (S)-PBO<sub>27</sub>-b-(S)-PG<sub>14</sub> by <sup>1</sup>H-NMR spectroscopy in methanol-d<sub>4</sub>. <strong>3. Figure 3</strong>: Zip archive containing the experimental data for <em>Figure 3</em>. Chiral characterisation of the atactic and isotactic BCPs. <strong>4. Figure 4</strong>: Zip archive containing the experimental data for <em>Figure 4</em>. TEM and Cryo-TEM characterisation of the SUVs formed by <em>(a)</em> (R/S)-PBO<sub>26</sub>-b-(R/S)-PG<sub>14</sub>, <em>(b)</em> (R)-PBO<sub>26</sub>-b-(R)-PG<sub>14</sub> and <em>(c)</em> (S)-PBO<sub>27</sub>-b-(S)-PG<sub>14</sub>. <strong>5. Figure 5</strong>: Zip archive containing the CLSM images for <em>Figure 5</em>. <strong>6. Figure 6</strong>: Zip archive containing the images for <em>Figure 6</em>. Snapshots of the enzyme reaction within the cavity of (R/S)-BCP GUVs <em>(b)</em> with and <em>(c)</em> without reconstituted membrane protein OmpF, recorded by CLSM at different time points <strong>7. Figure 7</strong>: Excel file containing the experimental data for <em>Figure 7</em>. Fluorescence intensity development of <em>(a)</em> (R/S)-BCP and <em>(b)</em> PDMS<sub>25</sub>-b-PMOXA<sub>10</sub> GUVs resulting from the reaction of resorufin β-D-galactopyranoside (RGP) with β-galactosidase (β-Gal) to yield fluorescent resorufin. <strong>8. Table 1</strong>: Zip archive containing the experimental data for <em>Table 1</em>. <strong>9. Table 2</strong>: Zip archive containing the experimental data for <em>Table 2</em>.
DOI: 10.5281/zenodo.5560880
title: Fully amorphous atactic and isotactic block copolymers and their self-assembly into nano- and microscopic vesicles

description: Data underlying the figures in the publication “Fully amorphous atactic and isotactic block copolymers and their self-assembly into nano- and microscopic vesicles”, published in <em>Polym. Chem., </em><em><strong>2021</strong></em><em>, 12, 5377-5389</em>. https://pubs.rsc.org/en/content/articlelanding/2021/PY/D1PY00952D Table of contents: <strong>1. Figure 1</strong>: Zip archive containing the experimental data (NMR spectra) for the kinetics of the PBO syntheses (<em>Figure 1c</em>) and the PBO-b-PEEGE syntheses (<em>Figure 1d</em>). <strong>2. Figure 2</strong>: Zip archive containing the experimental data for <em>Figure 2</em>. Structural characterisation of the (S)-BCP (S)-PBO<sub>27</sub>-b-(S)-PG<sub>14</sub> by <sup>1</sup>H-NMR spectroscopy in methanol-d<sub>4</sub>. <strong>3. Figure 3</strong>: Zip archive containing the experimental data for <em>Figure 3</em>. Chiral characterisation of the atactic and isotactic BCPs. <strong>4. Figure 4</strong>: Zip archive containing the experimental data for <em>Figure 4</em>. TEM and Cryo-TEM characterisation of the SUVs formed by <em>(a)</em> (R/S)-PBO<sub>26</sub>-b-(R/S)-PG<sub>14</sub>, <em>(b)</em> (R)-PBO<sub>26</sub>-b-(R)-PG<sub>14</sub> and <em>(c)</em> (S)-PBO<sub>27</sub>-b-(S)-PG<sub>14</sub>. <strong>5. Figure 5</strong>: Zip archive containing the CLSM images for <em>Figure 5</em>. <strong>6. Figure 6</strong>: Zip archive containing the images for <em>Figure 6</em>. Snapshots of the enzyme reaction within the cavity of (R/S)-BCP GUVs <em>(b)</em> with and <em>(c)</em> without reconstituted membrane protein OmpF, recorded by CLSM at different time points <strong>7. Figure 7</strong>: Excel file containing the experimental data for <em>Figure 7</em>. Fluorescence intensity development of <em>(a)</em> (R/S)-BCP and <em>(b)</em> PDMS<sub>25</sub>-b-PMOXA<sub>10</sub> GUVs resulting from the reaction of resorufin β-D-galactopyranoside (RGP) with β-galactosidase (β-Gal) to yield fluorescent resorufin. <strong>8. Table 1</strong>: Zip archive containing the experimental data for <em>Table 1</em>. <strong>9. Table 2</strong>: Zip archive containing the experimental data for <em>Table 2</em>.
DOI: 10.6084/m9.figshare.16782607
title: 京山土壤防治规划

description: 京山市土壤防止规划方案及附图
DOI: 10.6084/m9.figshare.16782607.v1
title: 京山土壤防治规划

description: 京山市土壤防止规划方案及附图
DOI: 10.48370/ofd/44cmdt
title: Morenoina paludosa J. P. Ellis, 1598

description: Fungarium Micromycetes
DOI: 10.5281/zenodo.5560920
title: Culturing Patient-Derived Malignant Hematopoietic Stem Cells in Engineered and Fully Humanized 3D Niches

description: Data underlying the figures in the publication “Culturing patient-derived malignant hematopoietic stem cells in engineered and fully humanized 3D niches”, published in <em>PNAS,</em><em> <strong>2021</strong>, 118 (40) e2114227118.</em> <em>DOI: 10.1073/pnas.2114227118</em> Table of contents: <strong>1. AML data_Gene expression</strong>: qPCR data related to AML samples. <strong>2. AML data_Protein</strong>: Luminex data related to AML samples. <strong>3. AML data_Supernatant vs Niche</strong>: FACS data comparing AML cells in the supernatant and niche compartments. <strong>4. AML data_Supernatant</strong>: FACS data showing AML cells in the supernatant along the time. <strong>5. Chemotherapy_2D_FACS</strong>: FACS data showing leukemic cell viability in 2D. <strong>6. Chemotherapy_3D_FACS</strong>: FACS data showing leukemic cell viability in 3D (engineered niches). <strong>7. MPN data</strong>: FACS data related to MPN samples. <strong>8. SV-N_FACS</strong>: FACS data characterizing SV-N. <strong>9. SV-N_Gene expression</strong>: qPCR data characterizing SV-N. <strong>10. UCSD-AML1_Niche_FACS</strong>: FACS data showing UCSD-AML1 cells in the niche at final analysis. <strong>11. UCSD-AML1_Niche_Gene expression</strong>: qPCR data showing UCSD-AML1 cells in the niche at final analysis. <strong>12. UCSD-AML1_Supernatant_FACS</strong>: FACS data showing UCSD-AML1 cells in the supernatant along the time. <strong>13. UCSD-AML1_Supernatant_Gene expression</strong>: qPCR data related to UCSD-AML1 cells in the supernatant along the time. <strong>14. UCSD-AML1_Supernatant_Protein</strong>: Luminex data related to UCSD-AML1 cells in the supernatant along the time. <strong>15. Images engineered niches</strong>: Zip archive containing images of engineered niches.
DOI: 10.5281/zenodo.5560919
title: Culturing Patient-Derived Malignant Hematopoietic Stem Cells in Engineered and Fully Humanized 3D Niches

description: Data underlying the figures in the publication “Culturing patient-derived malignant hematopoietic stem cells in engineered and fully humanized 3D niches”, published in <em>PNAS,</em><em> <strong>2021</strong>, 118 (40) e2114227118.</em> <em>DOI: 10.1073/pnas.2114227118</em> Table of contents: <strong>1. AML data_Gene expression</strong>: qPCR data related to AML samples. <strong>2. AML data_Protein</strong>: Luminex data related to AML samples. <strong>3. AML data_Supernatant vs Niche</strong>: FACS data comparing AML cells in the supernatant and niche compartments. <strong>4. AML data_Supernatant</strong>: FACS data showing AML cells in the supernatant along the time. <strong>5. Chemotherapy_2D_FACS</strong>: FACS data showing leukemic cell viability in 2D. <strong>6. Chemotherapy_3D_FACS</strong>: FACS data showing leukemic cell viability in 3D (engineered niches). <strong>7. MPN data</strong>: FACS data related to MPN samples. <strong>8. SV-N_FACS</strong>: FACS data characterizing SV-N. <strong>9. SV-N_Gene expression</strong>: qPCR data characterizing SV-N. <strong>10. UCSD-AML1_Niche_FACS</strong>: FACS data showing UCSD-AML1 cells in the niche at final analysis. <strong>11. UCSD-AML1_Niche_Gene expression</strong>: qPCR data showing UCSD-AML1 cells in the niche at final analysis. <strong>12. UCSD-AML1_Supernatant_FACS</strong>: FACS data showing UCSD-AML1 cells in the supernatant along the time. <strong>13. UCSD-AML1_Supernatant_Gene expression</strong>: qPCR data related to UCSD-AML1 cells in the supernatant along the time. <strong>14. UCSD-AML1_Supernatant_Protein</strong>: Luminex data related to UCSD-AML1 cells in the supernatant along the time. <strong>15. Images engineered niches</strong>: Zip archive containing images of engineered niches.