cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.1594/pangaea.958210
title: Nitrate and UV-absorbance spectra from ROV survey PS122/2_23-29 on 2020-02-04, survey 1

description: Nitrate and UV-absorbance spectra were measured by a SUNA V2 UV-spectrometer (Satlantic) mounted in the sensor skid of a remotely operated vehicle (ROV) during the Multidisciplinary drifting Observatory for the Study of Arctic Climate (MOSAiC) expedition between November 2019 and September 2020. Data use manufacturer calibration.
DOI: 10.1594/pangaea.958211
title: Nitrate and UV-absorbance spectra from ROV survey PS122/2_24-70 on 2020-02-11, survey 2

description: Nitrate and UV-absorbance spectra were measured by a SUNA V2 UV-spectrometer (Satlantic) mounted in the sensor skid of a remotely operated vehicle (ROV) during the Multidisciplinary drifting Observatory for the Study of Arctic Climate (MOSAiC) expedition between November 2019 and September 2020. Data use manufacturer calibration.
DOI: 10.1594/pangaea.958212
title: Nitrate and UV-absorbance spectra from ROV survey PS122/2_24-70 on 2020-02-11, survey 4

description: Nitrate and UV-absorbance spectra were measured by a SUNA V2 UV-spectrometer (Satlantic) mounted in the sensor skid of a remotely operated vehicle (ROV) during the Multidisciplinary drifting Observatory for the Study of Arctic Climate (MOSAiC) expedition between November 2019 and September 2020. Data use manufacturer calibration.
DOI: 10.1594/pangaea.958213
title: Nitrate and UV-absorbance spectra from ROV survey PS122/2_24-97 on 2020-02-15, survey 1

description: Nitrate and UV-absorbance spectra were measured by a SUNA V2 UV-spectrometer (Satlantic) mounted in the sensor skid of a remotely operated vehicle (ROV) during the Multidisciplinary drifting Observatory for the Study of Arctic Climate (MOSAiC) expedition between November 2019 and September 2020. Data use manufacturer calibration.
DOI: 10.1594/pangaea.958214
title: Nitrate and UV-absorbance spectra from ROV survey PS122/2_25-104 on 2020-02-22, survey 1

description: Nitrate and UV-absorbance spectra were measured by a SUNA V2 UV-spectrometer (Satlantic) mounted in the sensor skid of a remotely operated vehicle (ROV) during the Multidisciplinary drifting Observatory for the Study of Arctic Climate (MOSAiC) expedition between November 2019 and September 2020. Data use manufacturer calibration.
DOI: 10.1594/pangaea.958989
title: Video In Situ Snowfall Sensor (VISSS) status info for Ny-Ålesund for days without precipitation (2021-2022)

description: The VISSS is a camera system recording precipitating snowfall from two perspectives. Here, the status txt files are provided for all days without precipitation at station Ny-Ålesund. For further details on the VISS Sensor see Maahn et al. (2023).
DOI: 10.1594/pangaea.954136
title: Standardized radiocarbon data of sediment core PG2135 from Lake Ulakhan Chabyda (Yakutia, Russia)

description: This data set is part of a larger data harmonization effort to make lake sediment core data machine readable and comparable. Here we standardized radiocarbon age data of sediment core PG2135, retrieved in 2013 from Lake Ulakhan Chabyda (Yakutia, Russia) at 1.7 m water depth. The thermokarst lake Ulakhan Chabyda is in an exorheic basin in the coniferous forest area and has one outflow and several small inflows. It lies at an elevation of ca. 195 m a.s.l. with a surface area of ca. 2.1 km2 and a maximum lake water depth of estimated 2.1 m. The 6.51 m sediment core was retrieved by a Russian peat corer during the RU-Land_2013_Yakutia expedition of the Alfred Wegener Institute Helmholtz Centre for Polar and Marine Research (AWI, Germany, Potsdam) in cooperation with the North Eastern Federal State University (NEFU, Russia, Yakutsk). Radiocarbon data have been analysed in in the radiocarbon laboratory at AWI Bremerhaven (MICADAS).
DOI: 10.1594/pangaea.954143
title: Standardized grain size data of sediment core PG2135 from Lake Ulakhan Chabyda (Yakutia, Russia)

description: This data set is part of a larger data harmonization effort to make lake sediment core data machine readable and comparable. Here we standardized grain-size data of sediment core PG2135, retrieved in 2013 from Lake Ulakhan Chabyda (Yakutia, Russia) at 1.7 m water depth. The thermokarst lake Ulakhan Chabyda is in an exorheic basin in the coniferous forest area and has one outflow and several small inflows. It lies at an elevation of ca. 195 m a.s.l. with a surface area of ca. 21 km2 and a maximum lake water depth of estimated 2.1 m. The 6.51 m sediment core was retrieved by a Russian peat corer during the RU-Land_2013_Yakutia expedition of the Alfred Wegener Institute Helmholtz Centre for Polar and Marine Research (AWI, Germany, Potsdam) in cooperation with the North Eastern Federal State University (NEFU, Russia, Yakutsk). Grain-size was measured by Malvern Mastersizer 3000 laser diffraction particle analyser at AWI Potsdam.
DOI: 10.1594/pangaea.956859
title: Standardized radiocarbon ages of sediment core PG2201 from Lake Malaya Chabyda (Yakutia, Russia)

description: This data set is part of a larger data harmonization effort to make lake sediment core data machine readable and comparable. Here we standardized radiocarbon age data of sediment core PG2201, retrieved in 2013 from Lake Malaya Chabyda (Yakutia, Russia), located approximately 15 km southwest of the City of Yakutsk, at 2 m water depth. Lake Ulakhan Chabyda (Event: PG2315) discharges into Lake Malaya Chabyda during times of high water. The thermokarst lake Malaya Chabyda is in an exorheic basin in the coniferous forest area and has one outflow and one inflow. It lies at an elevation of ca. 192 m a.s.l. with a surface area of ca. 0.18 km2 and a maximum lake water depth of estimated 3 m. The sediment core was retrieved by a Russian peat corer during the RU-Land_2013_Yakutia expedition of the Alfred Wegener Institute Helmholtz Centre for Polar and Marine Research (AWI, Germany, Potsdam) in cooperation with the North Eastern Federal State University (NEFU, Russia, Yakutsk). Eight overlapping sediment cores, representing an approximately 6.6 m–long composite sequence were collected on March 24, 2013. Two parallel drilling holes, approximately 1 m apart, were used alternatingly to obtain core sections which overlap by approximately 20 cm. Radiocarbon data have been analysed in in the radiocarbon laboratory at AWI Bremerhaven (MICADAS).
DOI: 10.34740/kaggle/dsv/7910513
title: Layline Shareholder activism dataset
DOI: 10.1594/pangaea.965580
title: Standardized radiocarbon data of sediment core PG2360 from Lake Bety (Yakutia, Russia)

description: This data set is part of a larger data harmonization effort to make lake sediment core data machine readable and comparable. Here we standardized radiocarbon age data of sediment core PG2360, retrieved in 2016 from Lake Bety (Yakutia, Russia) at 1.5 m water depth. The thermokarst lake Bety is a small thermkarst lake in the coniferous forest area and has one outflow and three inflows. It lies at an elevation of ca. 160 m a.s.l. with a surface area of ca. 0.66 km2 and a maximum lake water depth of estimated 1.5 m. The 2.31 m sediment core was retrieved by a Russian peat corer during the RU-Land_2016_Yakutia Expedition of the Alfred Wegener Institute Helmholtz Centre for Polar and Marine Research (AWI, Germany, Potsdam) in cooperation with the North Eastern Federal State University (NEFU, Russia, Yakutsk). Radiocarbon data have been analysed in in the radiocarbon laboratory at AWI Bremerhaven (MICADAS).
DOI: 10.1594/pangaea.965582
title: Standardized diatom data of sediment core PG2360 from Lake Bety (Yakutia, Russia)

description: This data set is part of a larger data harmonization effort to make lake sediment core data machine readable and comparable. Here we standardized diatom count data of sediment core PG2360, retrieved in 2016 from Lake Bety (Yakutia, Russia) at 1.5 m water depth. The thermokarst lake Bety is a small thermkarst lake in the coniferous forest area and has one outflow and three inflows. It lies at an elevation of ca. 160 m a.s.l. with a surface area of ca. 0.66 km2 and a maximum lake water depth of estimated 1.5 m. The 2.31 m sediment core was retrieved by a Russian peat corer during the RU-Land_2016_Yakutia Expedition of the Alfred Wegener Institute Helmholtz Centre for Polar and Marine Research (AWI, Germany, Potsdam) in cooperation with the North Eastern Federal State University (NEFU, Russia, Yakutsk). Diatoms have been counted using a ZEISS light microsocope at 1000x magnification at AWI Potsdam, and valve concentration was detected using microspheres.
DOI: 10.1594/pangaea.965585
title: Standardized organic geochemistry of sediment core PG2360 from Lake Bety (Yakutia, Russia)

description: This data set is part of a larger data harmonization effort to make lake sediment core data machine readable and comparable. Here we standardized organic carbon data of sediment core PG2360, retrieved in 2016 from Lake Bety (Yakutia, Russia) at 1.5 m water depth. The thermokarst lake Bety is a small thermkarst lake in the coniferous forest area and has one outflow and three inflows. It lies at an elevation of ca. 160 m a.s.l. with a surface area of ca. 0.66 km2 and a maximum lake water depth of estimated 1.5 m. The 2.31 m sediment core was retrieved by a Russian peat corer during the RU-Land_2016_Yakutia Expedition of the Alfred Wegener Institute Helmholtz Centre for Polar and Marine Research (AWI, Germany, Potsdam) in cooperation with the North Eastern Federal State University (NEFU, Russia, Yakutsk). Organic carbon, inorganic carbon, and nitrogen from the sediment samples was analyzed in the laboratories of AWI Potsdam.
DOI: 10.1594/pangaea.965792
title: Radiosonde measurements from station Tateno (2023-11)
DOI: 10.1594/pangaea.965793
title: Radiosonde measurements from station Tateno (2023-12)
DOI: 10.1594/pangaea.965794
title: Meteorological synoptical observations from station Tateno (2023-12)
DOI: 10.1594/pangaea.965795
title: Meteorological synoptical observations from station Tateno (2023-11)
DOI: 10.5517/ccdc.csd.cc2gsdj6
title: CCDC 2287568: Experimental Crystal Structure Determination

description: Related Article: Lei Zhang, Taotao Xiao, Xiayun Zeng, Jianjun You, Ziyu He, Cheng-Xia Chen, Qianting Wang, Ayman Nafady, Abdullah M. Al-Enizi, Shengqian Ma|2024|J.Am.Chem.Soc.|146|7341|doi:10.1021/jacs.3c12032
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.25913/2kvm-z442
title: Rapid Iron Infusion study primary outcome dataset

description: HeSANDA 1.0.0
description: Baseline randomisaton data (Hb, MCV, age gender, primary hospital diagnosis), risk factors at randomisation, randomisation allocation and treatment received, Hb at 1 and 6-9 months follow up, other iron supplementation during follow up.
DOI: 10.6084/m9.figshare.24473005
title: Synthetic augmentation of cancer cell line multi-omic datasets using unsupervised deep learning: Feature Importance

description: The calculated SHAP values for "Augmented cancer cell map using synthetic multi-omics".
DOI: 10.6084/m9.figshare.24473005.v1
title: Synthetic augmentation of cancer cell line multi-omic datasets using unsupervised deep learning: Feature Importance

description: The calculated SHAP values for "Augmented cancer cell map using synthetic multi-omics".
DOI: 10.25913/abnr-kn72
title: PREVIX_COMBO Primary outcomes

description: HeSANDA 1.0.0
description: Demographics - Location - Ethnicity (all Australian First Nations) Baseline / randomisation characteristics (Table 1 in publication) - Birth characteristics (birth weight, gestational age, maternal smoking) - Randomisation characteristics (weight, age, family history 'runny ears', breastfeeding status, household smoking, environmental smoke) Randomisation allocation (vaccine group) Pneumococcal vaccines given (vaccine type, age at vaccination) Age per visit Immunology - Serotype specific IgG - Protein D ELISA Otitis Media status per visit (age at visit)
DOI: 10.5281/zenodo.10851476
title: Dataset for the  HYCOM ISV in the upper ocean
DOI: 10.5281/zenodo.10851477
title: Dataset for the  HYCOM ISV in the upper ocean
DOI: 10.25913/s2y4-7f79
title: PREVIX_BOOST Primary outcomes

description: HeSANDA 1.0.0
description: Demographics - Location - Ethnicity (all Australian First Nations) Baseline / randomisation characteristics (Table 1 in publication) - Birth characteristics (birth weight, gestational age, maternal smoking) - Randomisation characteristics (weight, age, family history 'runny ears', breastfeeding status, household smoking, environmental smoke) Randomisation allocation (vaccine group) Pneumococcal vaccines given (vaccine type, age at vaccination) Age per visit Immunology - Serotype specific IgG - Protein D ELISA Otitis Media status per visit (age at visit)
DOI: 10.5517/ccdc.csd.cc2gzzwb
title: CCDC 2293903: Experimental Crystal Structure Determination

description: Related Article: Swati Samantaray, Prabhat Kumar Maharana, Subhradeep Kar, Sharajit Saha, Tharmalingam Punniyamurthy|2024|Chem.Commun.|60|3441|doi:10.1039/D4CC00226A
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.6084/m9.figshare.25458862.v1
title: The data needed for the experiment

description: Road network selection is a key focus in the field of cartographic generalization. With the rapid updating of road data, there are higher requirements for the quality and intelligence of road selection. Based on the knowledge graph composition method, this article combines graph neural networks to achieve automatic selection of road networks.
DOI: 10.6084/m9.figshare.9848972.v3
title: Tandem RNA isolation reveals functional rearrangement of RNA-binding proteins on <i>CDKN1B/p27</i><sup>Kip1</sup> 3’UTRs in cisplatin treated cells

description: Post-transcriptional control of gene expression is mediated via RNA-binding proteins (RBPs) that interact with mRNAs in a combinatorial fashion. While recent global RNA interactome capture experiments expanded the repertoire of cellular RBPs quiet dramatically, little is known about the assembly of RBPs on particular mRNAs; and how these associations change and control the fate of the mRNA in drug-treatment conditions. Here we introduce a novel biochemical approach, termed tobramycin-based tandem RNA isolation procedure (tobTRIP), to quantify proteins associated with the 3ʹUTRs of cyclin-dependent kinase inhibitor 1B (<i>CDKN1B/p27<sup>Kip1</sup></i>) mRNAs <i>in vivo</i>. P27<sup>Kip1</sup> plays an important role in mediating a cell’s response to cisplatin (CP), a widely used chemotherapeutic cancer drug that induces DNA damage and cell cycle arrest. We found that <i>p27<sup>Kip1</sup></i> mRNA is stabilized upon CP treatment of HEK293 cells through elements in its 3ʹUTR. Applying tobTRIP, we further compared the associated proteins in CP and non-treated cells, and identified more than 50 interacting RBPs, many functionally related and evoking a coordinated response. Knock-downs of several of the identified RBPs in HEK293 cells confirmed their involvement in CP-induced <i>p27</i> mRNA regulation; while knock-down of the KH-type splicing regulatory protein (KHSRP) further enhanced the sensitivity of MCF7 adenocarcinoma cancer cells to CP treatment. Our results highlight the benefit of specific <i>in vivo</i> mRNA-protein interactome capture to reveal post-transcriptional regulatory networks implicated in cellular drug response and adaptation.
DOI: 10.6084/m9.figshare.9848972
title: Tandem RNA isolation reveals functional rearrangement of RNA-binding proteins on <i>CDKN1B/p27</i><sup>Kip1</sup> 3’UTRs in cisplatin treated cells

description: Post-transcriptional control of gene expression is mediated via RNA-binding proteins (RBPs) that interact with mRNAs in a combinatorial fashion. While recent global RNA interactome capture experiments expanded the repertoire of cellular RBPs quiet dramatically, little is known about the assembly of RBPs on particular mRNAs; and how these associations change and control the fate of the mRNA in drug-treatment conditions. Here we introduce a novel biochemical approach, termed tobramycin-based tandem RNA isolation procedure (tobTRIP), to quantify proteins associated with the 3ʹUTRs of cyclin-dependent kinase inhibitor 1B (<i>CDKN1B/p27<sup>Kip1</sup></i>) mRNAs <i>in vivo</i>. P27<sup>Kip1</sup> plays an important role in mediating a cell’s response to cisplatin (CP), a widely used chemotherapeutic cancer drug that induces DNA damage and cell cycle arrest. We found that <i>p27<sup>Kip1</sup></i> mRNA is stabilized upon CP treatment of HEK293 cells through elements in its 3ʹUTR. Applying tobTRIP, we further compared the associated proteins in CP and non-treated cells, and identified more than 50 interacting RBPs, many functionally related and evoking a coordinated response. Knock-downs of several of the identified RBPs in HEK293 cells confirmed their involvement in CP-induced <i>p27</i> mRNA regulation; while knock-down of the KH-type splicing regulatory protein (KHSRP) further enhanced the sensitivity of MCF7 adenocarcinoma cancer cells to CP treatment. Our results highlight the benefit of specific <i>in vivo</i> mRNA-protein interactome capture to reveal post-transcriptional regulatory networks implicated in cellular drug response and adaptation.
DOI: 10.6084/m9.figshare.25458076
title: RefEx2 Datasets for Human GTEx v8

description: RefEx2 is a project to collect, organize, and curate transcriptome datasets of various species as reference resources for gene expression data analysis. It provides 6 reference datasets for four different species: humans, mice, Drosophila melanogaster, and Arabidopsis thaliana. This directory contains the following datasets on human GTEx v8:220404_gtex_v8_refextable_sample_stats.tsv.gzProcessed data matrix220404_gtex_v8_summarized_refextable_sample_stats.tsv.gzProcessed data matrix (summarized ver.) gtex_v8_refextable_grouped_sample_desc.tsvGrouped sample descriptiongtex_v8_summarized_refextable_grouped_sample_desc.tsvGrouped sample description (summarized ver.) gtex_v8_refextable_sampleID_mapping.tsvSample ID mappingsgtex_v8_summarized_refextable_sampleID_mapping.tsvSample ID mappings (summarized ver.) No. of genes: 56,161<br>No. of samples: 638<br>Key ID: Ensembl geneOriginal data: GTEx_Analysis_2017-06-05_v8_RNASeQCv1.1.9_gene_tpm.gct.gz<br>Reference(s): DOI: 10.1126/science.aaz1776
DOI: 10.6084/m9.figshare.19203410
title: Flexible pri-miRNA structures enable tunable production of 5’ isomiRs

description: The Drosha cleavage of a pri-miRNA defines mature microRNA sequence. Drosha cleavage at alternative positions generates 5’ isoforms (isomiRs) which have distinctive functions. To understand how pri-miRNA structures influence Drosha cleavage, we performed a systematic analysis of the maturation of endogenous pri-miRNAs and their variants both <i>in vitro</i> and <i>in vivo</i>. We show that in addition to previously known features, the overall structural flexibility of pri-miRNA impact Drosha cleavage fidelity. Internal loops and nearby G · U wobble pairs on the pri-miRNA stem induce the use of non-canonical cleavage sites by Drosha, resulting in 5’ isomiR production. By analysing patient data deposited in the Cancer Genome Atlas, we provide evidence that alternative Drosha cleavage of pri-miRNAs is a tunable process that responds to the level of pri-miRNA-associated RNA-binding proteins. Together, our findings reveal that Drosha cleavage fidelity can be modulated by altering pri-miRNA structure, a potential mechanism underlying 5’ isomiR biogenesis in tumours. Graphical Abstract
DOI: 10.6084/m9.figshare.19203410.v1
title: Flexible pri-miRNA structures enable tunable production of 5’ isomiRs

description: The Drosha cleavage of a pri-miRNA defines mature microRNA sequence. Drosha cleavage at alternative positions generates 5’ isoforms (isomiRs) which have distinctive functions. To understand how pri-miRNA structures influence Drosha cleavage, we performed a systematic analysis of the maturation of endogenous pri-miRNAs and their variants both <i>in vitro</i> and <i>in vivo</i>. We show that in addition to previously known features, the overall structural flexibility of pri-miRNA impact Drosha cleavage fidelity. Internal loops and nearby G · U wobble pairs on the pri-miRNA stem induce the use of non-canonical cleavage sites by Drosha, resulting in 5’ isomiR production. By analysing patient data deposited in the Cancer Genome Atlas, we provide evidence that alternative Drosha cleavage of pri-miRNAs is a tunable process that responds to the level of pri-miRNA-associated RNA-binding proteins. Together, our findings reveal that Drosha cleavage fidelity can be modulated by altering pri-miRNA structure, a potential mechanism underlying 5’ isomiR biogenesis in tumours. Graphical Abstract
DOI: 10.6084/m9.figshare.19723092
title: Upon heat stress processing of ribosomal RNA precursors into mature rRNAs is compromised after cleavage at primary P site in <i>Arabidopsis thalian</i>a

description: Transcription and processing of 45S rRNAs in the nucleolus are keystones of ribosome biogenesis. While these processes are severely impacted by stress conditions in multiple species, primarily upon heat exposure, we lack information about the molecular mechanisms allowing sessile organisms without a temperature-control system, like plants, to cope with such circumstances. We show that heat stress disturbs nucleolar structure, inhibits pre-rRNA processing and provokes imbalanced ribosome profiles in <i>Arabidopsis thaliana</i> plants. Notably, the accuracy of transcription initiation and cleavage at the primary P site in the 5’ETS (5’ External Transcribed Spacer) are not affected but the levels of primary 45S and 35S transcripts are, respectively, increased and reduced. In contrast, precursors of 18S, 5.8S and 25S RNAs are rapidly undetectable upon heat stress. Remarkably, nucleolar structure, pre-rRNAs from major ITS1 processing pathway and ribosome profiles are restored after returning to optimal conditions, shedding light on the extreme plasticity of nucleolar functions in plant cells. Further genetic and molecular analysis to identify molecular clues implicated in these nucleolar responses indicate that cleavage rate at P site and nucleolin protein expression can act as a checkpoint control towards a productive pre-rRNA processing pathway.