cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17632/mwgxv7m927
title: Genetic and epigenetic regulation of mouse pancreatic islets by dietary intervention

description: In this study, we established a mouse prediabetic dietary intervention model by switching high fat diet (HFD) to normal chow diet at the prediabetic stage (HFD-CHOW group). Mice continuously fed with normal chow diet (CHOW group) or HFD (HFD group), to mimic the healthy diet or non-intervened conditions, respectively, were used as control groups to understand the genetic and epigenetic networks underlying the dietary intervention-mediated improvement of pancreatic islet β-cell function. This dataset contains processed RNA Seq, scRNA-Seq, ATAC-Seq, and CUT&Tag-Seq data from mouse (Mus musculus) islets. Details in sample collection and data analysis pipeline can be found in the Method section of the manuscript. Wild-type male C57BL/6J mice from the Jackson laboratory at 12-15 weeks of age were subjected to the above treatments for up to 6 months, followed by islet isolation and the subsequent experiments.

RNA-Seq:
	HFD_Time_scale.csv: Islet RNA-Seq data from mice fed with HFD for 1, 2, 3, and 6 months and their respective chow diet fed controls, in 2 technical replicates. Islets were pooled from at least 3 individual animals.
	Chow_HFD_HFDtoChow.csv: Islet RNA-Seq data from mice of CHOW group, HFD group, and HFD-CHOW group, in 2 technical replicates. Islets were pooled from at least 3 individual animals.

ScRNA-Seq:
	Chow.txt, HFD.txt and HFDtoChow.txt: Digital Expression Matrix (dge) of islet scRNA-Seq from mice of CHOW group, HFD group, and HFD-CHOW group. Islets were pooled from at least 3 individual animals.

ATAC-Seq:
	Chow.bw, HFD.bw and HFDtoChow.bw: BigWig files of islet ATAC-seq from mice of CHOW group, HFD group, and HFD-CHOW group. Islets were pooled from at least 3 individual animals.

CUT&Tag-Seq:
CTCF binding profile in mouse islets
	CTCF_binding_profile_in_murine_islet.bw: BigWig files of islet CTCF CUT&Tag-Seq from mice fed with chow diet for 9 months. Islets were pooled from at least 3 individual animals.
CTCF binding differences in mouse islets between CHOW and HFD groups
	Chow_islet_CTCF.bw: BigWig files of islet CTCF CUT&Tag-Seq from mice fed with chow diet for 6 months, in 2 technical replicates. Islets were pooled from at least 3 individual animals.
	Chow_islet_IgG.bw: BigWig files of islet IgG CUT&Tag-Seq from mice fed chow diet for 6 months. Islets were pooled from at least 3 individual animals.
	HFD_islet_CTCF.bw: BigWig files of islet CTCF CUT&Tag-Seq from mice fed with HFD for 6 months, in 3 technical replicates. Islets were pooled from at least 3 individual animals.
	HFD_islet_IgG.bw: BigWig files of islet IgG CUT&Tag-seq from mice fed with HFD for 6 months. Islets were pooled from at least 3 individual animals.
DOI: 10.17632/6d8kfnndng
title: Anchors test database

description: the file contains the results of tensile confined and unconfined tests of bonded anchors
DOI: 10.17632/h4k9tk8y53
title: Oxidative Bursts of Single Mitochondria Mediate Retrograde Signaling towards the ER

description: Fig1A: Whole field Airyscan fluorescence image of HepG2 cell loaded with TMRE imaged with 514nm excitation. Fig1B&C: Images of cell from Fig1A + 6s/369s time lapse showing flicker events in single mitochondria, & uncropped difference images from inset. Difference images highlight changing TMRE signal red = decrease, blue = increase. Fig1I: 490nm excitation fluorescence images of HepG2 cells loaded with Calcein-AM/Co2+ before/after 1200s treatment with ST +/- cyclosporine A (CsA). Fig1K: Uncropped difference (TMRE) and overlay (Matrix-targeted SypHer) images. Overlay created from ratiometric imaging at 415nm & 485nm of SypHer. 415nm emission is colored green and 485nm red. Fig2D: 2 kymograph images of TMRE (Upper: mpl-inferno LUT) & Grx1roGFP2 (Lower, Greenfireblue LUT). Source image of TMRE with segmented line ROI used to create kymograph images. Fig2E: Uncropped difference (TMRE, upper) & overlay (Grx1roGFP2, lower) images of flicker event un unstimulated HepG2 cell. Overlay derived from 415nm (red; oxidized) & 485nm (green; reduced) emission from Grx1roGFP2. G: Uncropped difference & overlay images of flicker event from HepG2 cell stimulated with staurosporine (ST, 2µM). Fig3E: Uncropped SypHer/RCaMP images covering the time period displayed. Difference images highlight changing SypHer ratio (Green = SypHer 485nm emission increase, red = decrease) & RCaMP emission (blue = increase, red = decrease). Time resolution is 2s/frame. Fig3F: Original composite image created by integrating RCaMP 577nm emission signals and displaying result in 16_colors LUT overlaid onto grayscale cell image. Uncropped grayscale source images also included. Fig4G: Original TMRE 577nm emission fluorescence images & FRET emission images presented in 16_colors LUT. FigS1A: Uncropped 577nm emission images of TMRE stained HepG2 cells at t = 0 & t = 1200s in control (Ctrl) or staurosporine (ST) treated conditions. FigS1B: Uncropped difference images of flicker event in TMRE stained HepG2 cell. FigS4D: Uncropped composite images of time course presented. Images are of HepG2 cells stained with Hoechst 33321, CellEvent caspase substrate and TMRE imaged at 405,488 & 561nm excitation. FigS4J: Uncropped FRET images presented in 16_colors LUT.
DOI: 10.17632/vkvr849zkg
title: LINF_130016000

description: Leucyl-tRNA synthetase | LeuRS; Leishmania infantum (strain JPCM5)
DOI: 10.17632/yb8c57yf6m
title: Normative value of core muscle strength using sphygmomanometer

description: Background:
Core muscles are crucial for ensuring stability and strength in the abdominal, trunk, and lumbopelvic regions. College students often experience lower back pain due to sedentary lifestyles, prolonged computer usage, intense study habits, and incorrect sitting postures. Core stabilization exercises are effective in strengthening deep abdominal muscles using the abdominal drawing-in maneuver (ADIM). A sphygmomanometer is frequently used to evaluate core muscle strength. The mechanical low back pain scale (MLBP) and the straight leg raise test (SLR) are two reliable diagnostic techniques used to determine the severity of mechanical low back pain. 
Aim and objective: 
This study aims to investigate the normative value of core strength in participants with MLBP.
Materials and Methods: 
A total of 116 females participants were recruited based on inclusion and exclusion criteria. The participants had mechanical low back pain and were between 18-25 years of age. Sphygmomanometer was used to check the core muscle strength, three trials of 10 seconds and with a one minute of rest required between each trail. It took 5- 8 minutes to obtain the higher pressure reading. The baseline characteristics were calculated using KOLMOGOROV and analyzed data with SPSS software. The median with interquartile range (IQR) was used to determine the values of core strength.
Results and discussion: 
A normative value of core muscle strength was observed in female participants, in the supine position, with a median rank of 65.00 with an interquartile range (IQR) of 60.00-70.00 in participants with mechanical low back pain. 
Conclusion: 
The study concluded that sphygmomanometer is effective for the clinical use due to its portability, comfort and cost effectiveness, and ability to provide accurate measurement of core muscle strength with abdominal drawing-in maneuver technique in participants with mechanical low back pain.
Keywords: 
Sphygmomanometer, core muscle strength, core stability, mechanical low back pain
DOI: 10.6084/m9.figshare.13153826.v1
title: Supplementary Material for: The Real Impact of Bridging or Downstaging on Survival Outcomes after Liver Transplantation for Hepatocellular Carcinoma

description: <b><i>Introduction:</i></b> There is no consensus regarding selection criteria on liver transplantation (LT) for hepatocellular carcinoma (HCC), especially for living donor liver transplantation, although emerging evidence has been found for the effectiveness of bridging or downstaging. <b><i>Objective:</i></b> We evaluated the long-term outcomes of patients who underwent LT with or without bridging or downstaging for HCC. <b><i>Methods:</i></b> This retrospective study included 896 LT recipients with HCC between June 2005 and May 2015. Recurrence-free survival (RFS), overall survival (OS), and their associated factors were evaluated. <b><i>Results:</i></b> The 5-year RFS in the full cohort of 896 patients was 82.4%, and the OS was 85.3%. In patients with initial Organ Procurement and Transplantation Network (OPTN) T1 and T2, the 5-year RFS and OS did not significantly differ between LT groups with and without bridging (all <i>p</i> ≥ 0.05). The 5-year RFS and OS of OPTN T3 patients with successful downstaging were not significantly different from those of patients with OPTN T2 with primary LT (<i>p</i> = 0.070 and <i>p</i> = 0.185), but were significantly higher than in patients with OPTN T3 with downstaging failure and initial OPTN T1 or T2 with progression (all <i>p</i> &lt; 0.001). In the multivariate analysis, last alpha-fetoprotein before LT ≥70 ng/mL (hazard ratio [HR]: 1.77, <i>p</i> = 0.001; HR: 1.72, <i>p</i> = 0.004), pretransplant HCC status exceeding the Milan criteria (HR: 5.12, <i>p</i> &lt; 0.001; HR: 3.31, <i>p</i> &lt; 0.001), and positron emission tomography positivity (HR: 2.57, <i>p</i> &lt; 0.001; HR: 2.57, <i>p</i> &lt; 0.001) were independent predictors for worse RFS and OS. <b><i>Conclusions:</i></b> The impact of bridging therapy on survival outcomes is limited in patients with early-stage HCC, whereas OPTN T1 or T2 with progression provides worse prognosis. OPTN T3 should undergo LT after successful downstaging, and OPTN T3 with successful downstaging allows for acceptable long-term posttransplant outcomes.
DOI: 10.17632/x7nrbr98yt
title: Dataset: Stem diameter and total tree height for estimate above-ground biomass using different soil classes and forest types in the Serra da Mocidade National Park, northern Brazilian Amazonia

description: The dataset provides information on tree stem diameter (≥ 10cm) and total tree height (m) for estimate above-ground biomass in different soil classes and forest types of the Serra da Mocidade National Park, state of Roraima, northern Brazilian Amazonia. Our sampling took into consideration 707 initial trees (all of them alive) observed in the Trilha do Gato, a 2.7 km transect (31.1-64.8 m a.s.l.) crossing three different forest types: (i) mosaic between treed and forested shade-loving (La+Ld), (ii) area of ecological tension between forested shade-loving and open ombrophilous forest (LO) and (iii) open ombrophilous forest (Ab+As). The sampled area for each forest type was 0.530 ha (Ab+As), 0.334 ha (LO) and 0.192 ha (La+Ld). All tress/palms were measured annually among June/2016 and May/2018 (stem diameter in 2016-2018, and total height only in 2018). Soil classes are related to flooding periodicity for each forest type observed: Entisols Fluvents (La+Ld, 3-4 months flooded), Entisols Quartzipsamments (LO, 1-2 months) and Yellow Ultisols (Ab+As, no flooding), as specified by Beltrán-Alemán et al. (2019) in International Journal of Plant & Soil Science, 28(6): 1-11. Our dataset has one file (serra_da_mocidade.xlx) where are presented the code for each sampled tree/palm (treeID), associated to its taxonomic identification (family; species), sampling date, altitude (m a.s.l.), flooding periodicity, POM (point of measure of stem diameter), forest type, soil class, stem diameter (cm), and total height (m). The dataset was supported by the project “Crescimento e mortalidade de árvores em ecótonos determinados por limitações hidroedáficas do centro-sul de Roraima” (PPI-INPA). The Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq – Brazil) provided a fellowship for R. I. Barbosa (CNPq 304204/2015-3). L. A. Beltrán-Alemán was supported by a postgraduate fellowship from the Organization of American States (OAS). Instituto Chico Mendes de Conservação da Biodiversidade (ICMBio) provided authorization for the study (SISBIO n. 54221-2) in the Serra da Mocidade National Park.
DOI: 10.6084/m9.figshare.24760734.v2
title: Decoupled terrestrial temperature and hydroclimate in the East Asian Monsoonal region since the late Miocene

description: The GDGT indices of XA3 drill core and the reconstructed temperature of XA3 drill core (this study) and the tropical and midlatitude from West Pacific since 6.0 Ma
DOI: 10.17632/zfnvv74cr3
title: Data for: Evolution of the Western Ethiopian Shield revealed through U-Pb geochronology, petrogenesis, and geochemistry of syn-tectonic intrusive rocks

description: LA-ICP-MS UPb data of silicic intrusive rocks from the Dabana pluton, Western Ethiopian Shield.
DOI: 10.6084/m9.figshare.22047281.v1
title: Supplementary Material for: Assessment of Change in Practice of Routine Tracheal Suctioning Approach of Non-Vigorous Infants Born through Meconium-Stained Amniotic Fluid: A Pragmatic Systematic Review and Meta-Analysis of Evidence outside Randomized Trials

description: <b><i>Aim:</i></b> The 2015 recommendation of the International Liaison Committee on Resuscitation of no routine tracheal suctioning in non-vigorous neonates born through meconium-stained amniotic fluid (MSAF) was based on very low certainty of evidence (CoE) necessitating ongoing monitoring. The aim of this systematic review was to perform a meta-analysis of observational studies comparing the effect of implementing immediate resuscitation without routine tracheal suctioning versus with routine suctioning in neonates born through MSAF. <b><i>Methods:</i></b> MEDLINE, Embase, CENTRAL, and Web of Science were searched. Observational studies with a before-and-after design were included. Two authors extracted data independently. CoE based on GRADE recommendations was performed. <b><i>Results:</i></b> 13 studies were included. Clinical benefit or harm could not be excluded for the composite primary outcome of mortality or requirement of extracorporeal membranous oxygenation (ECMO) (relative risk, 95% confidence interval: 0.74 [0.47–1.17]), and mortality (0.68 [0.42–1.11]). “Routine tracheal suctioning” epoch had possibly lesser risk of meconium aspiration syndrome (MAS) when compared to “no routine tracheal suctioning” epoch (0.68 [0.47–0.99]). “Routine tracheal suctioning” epoch also possibly had a lower risk of hospital admission for respiratory symptoms, requirement of non-invasive respiratory support, invasive mechanical ventilation, surfactant treatment, air leak, and low-flow oxygen therapy. Clinical benefit or harm could not be excluded for the outcome of mortality or ECMO among those diagnosed with MAS (1.09 [0.86–1.39]), but “routine tracheal suctioning” was possibly associated with lower risk of respiratory morbidities among those diagnosed with MAS. The CoE was very low for most of the outcomes evaluated. <b><i>Conclusions:</i></b> Due to the very low CoE for the outcomes evaluated, no definitive conclusions can be drawn warranting the need for additional studies.
DOI: 10.17632/fcfcyry9mn
title: dataset FNE-PAS

description: Dataset for FNES-PAS
DOI: 10.6084/m9.figshare.27853662.v1
title: Transverse magnetoconductance in two-terminal chiral spin-selective devices

description: In the transverse CISS measurement geometry, the magnetization is normal to the current. Transverse spin polarization has been found, even in the absence of electromagnetochiral effects. The CISS signal also satisfies Onsager's reciprocity.
DOI: 10.17632/2xg8y52skn
title: Multimodal Assessment of Spasticity Using a Point-of-Care Instrumented Glove  to Separate Neural and Biomechanical Contributions 

description: 21 patients data used in this paper. **Important: please go over the readme file before use**
DOI: 10.17632/s5grp9pgmw
title: Attitudes toward statistics-Tabulation Data

description: This data represents students' attitudes towards statistics before and after learning, academic achievements, and student demographic background (study program (hospitality, travel, and tourism); class levels; gender; origin of high school; study program in high school; and work experience).
DOI: 10.17632/4yhc64z9n2
title: Effect of human attachment style on horse behaviour and physiology during equine-assisted activities

description: H0: human attachment style (AS) will affect horse behaviour and heart rate during a 10-week equine-facilitated learning program. AS of at-risk youth was scored on anxiety and avoidance to determine category (low anxiety and avoidance = secure; low anxiety high avoidance = dismissing; high anxiety low avoidance = preoccupied; high anxiety and avoidance = fearful). Youth were paired for grooming sessions (G) and rode individually during arena sessions (A). Horse behaviours (oral, avoidance, affiliative) were captured by 0/1 interval sampling every 5sec for 2min windows during G and A. Horse heart rate (HR) was averaged in 5sec intervals. horse gait (halt (H), walk (W), back up (B)) was noted every 5sec during arena sessions. Adolescents’ AS affected horse affiliative behaviour during grooming, and horse heart rate and avoidance behaviour during riding. Over the 10-week program, therapy horses showed overall more affiliative behaviour and less variability in their stress response (heart rate and avoidance behaviours) toward fearful and preoccupied AS adolescents during grooming and riding.
DOI: 10.17632/wtpbtk5w6z
title: Russian consumer consumption survey on ozon platform

description: This survey randomly selected a sample of 20x Russian consumers to investigate their consumption behaviors and problems on the ozon platform
DOI: 10.6084/m9.figshare.3528779.v1
title: Appendix B. Three tables presenting full statistical results for the meta-analysis on grazer effects on the absolute and relative spatial heterogeneity of algal biomass.

description: Three tables presenting full statistical results for the meta-analysis on grazer effects on the absolute and relative spatial heterogeneity of algal biomass.
DOI: 10.17632/g5bz4r3zxb
title: Replication materials for Bartelme, D, Lan, T, and Levchenko, A, "Specialization, Market Access and Real Income"

description: This package contains the replication materials for Bartelme, D, Lan, T, and Levchenko, A, "Specialization, Market Access and Real Income." Please consult the article for the descriptions of the findings, and the readme file for details on how to run the code.
DOI: 10.17608/k6.auckland.11750721.v3
title: Title

description: Description
DOI: 10.17632/5gj8hkt4n2
title: Data: Host migration strategy and blood parasite infections of three sparrow species sympatrically breeding in Southeast Europe
DOI: 10.17632/b44mhb82nr
title: Reconstructing Deposits and Recontextualising Artefacts at Creag a' Chapuill Cave, Skye

description: This dataset contains a 3D model of Creag a' Chapuill cave, Skye, Scotland. The 1932 excavation at Creag a' Chapuill cave by W. Lindsay Scott revealed significant archaeological evidence with the potential to inform archaeologists about settlement and trading contacts along the western seaboard of Scotland. 3D Computer Aided Design (CAD) software, Graphical Information Systems (GIS) and legacy data was used to virtually reconstruct excavated deposits and recontextualise artefacts. Volumetric analysis revealed a high density of worked-stone (225 artefacts per m3) in Region 4C and a high slag density in Regions 4B (17.2 kg/m3), 4C (5.6 kg/m3) and 2B (1.4 kg per m3). Exploratory Spatial Data Analysis (ESDA) was used to detect potential patterns of artefact distribution in order to investigate the degree and extent of disturbance at the time of excavation, chronological phases, and activity areas. Join count statistic indicated global spatial autocorrelation within the worked-stone (z-score = -2.144) and Bronze Age pottery (z-score = -2.109) data and Local Moran’s I statistic indicated local spatial autocorrelation within the worked-stone and slag data. The data can be used to confirm patterns recognised by the original excavator, as well as revealing new patterns which highlight the complex depositional and post-depositional formation of the cave deposits. This allows easier comparisons to be made with more recently excavated sites therefore increasing our understanding of the local prehistoric landscape and contributing to our knowledge of prehistoric cave use within Scotland.
DOI: 10.6084/m9.figshare.1101888.v1
title: Physiological constraints to climate change: insights from the effects of temperature on standard metabolic rate in larval salamanders

description: 1. Predictions of climate change susceptibility are critical in forming conservation policy. However, these predictions may not be generalized even among sister taxa. As such, the development of species-specific, quantitative predictors of sensitivity to thermal increases is vital to the proper allocation of conservation resources and priorities. Climatic variability hypotheses propose that species occupying larger geographic ranges should develop more robust physiological tolerances and be more resistant to temperature changes. 2. In this study, we investigated the effects of temperature variation on standard metabolic rates (SMR) of two species of larval salamanders, Eurycea cirrigera and E. wilderae, that share similar life histories but occupy distinct ranges of variable sizes. 3. To this end, SMR was determined using volume of oxygen consumption during closed-circuit respirometery trials conducted at 5 °C increments between 5 and 25 °C. 4. Standard metabolic rates were influenced by temperature, with a range of temperature-independent SMRs observed at those temperatures above each species’ laboratory-determined thermal preference. Concordant with their thermal preference (15.70 °C) and more narrow geographic range, E. wilderae exhibited a smaller scope of temperatures at which SMR was temperature-independent relative to E. cirrigera and showed depressed metabolic rates at the highest temperature tested. 5. Our results provide a mechanistic link for an ecological predictor of climate change susceptibility (i.e., range size) and indicate that physiological specialization that occurs in species of narrow geographic ranges may preclude adaptations to climate change.
DOI: 10.17632/vrm3wvt89b
title: LINF_140020900

description: Protein of unknown function - conserved | WCB; Leishmania infantum (strain JPCM5)
DOI: 10.17632/spvxfsmkps
title: PPK of FSH

description: Data for FSH PPK model building
DOI: 10.17632/y5x5jjp8bn
title: Heat stress during the transition period is associated with impaired production, reproduction, and survival in dairy cows

description: Supplemental tables
DOI: 10.17632/8kz8chx39f
title: Tellus dataset

description: The data were acquired through the IoT system using GPRS/2G between August to December crop 2021 during the tobacco plantation. The images are collected from 8 AM to 6 PM in 2/2 hours. The soil and microclimate data were collected all day in each 30 minutes. 
The telemetry station consisted of a solar controller connected between a 30 W solar plate (model RSM030P) and a 12V battery with a capacity of 12 Ah that powered a Raspberry Pi Model A+ device. Connected to the Raspberry was a sensor model BME-280, which carried out measurements of ambient temperature and humidity in addition to atmospheric pressure, a 2G/GSM modem model SIM808L and an Arduino model UNO. A relay model SRD-05 (5V 10A) turned on the Arduino periodically to send a set of information to the Raspberry via USB. In this set, that is, connected to the Arduino, there were the other sensors that collected data on soil temperature (model Ds18b20) and soil moisture (hygrometer model S12), luminosity (model Temt6000), direction and speed of the winds (WRF Commercial) .
DOI: 10.17632/jggdkrpxts
title: Alzheimer’s vulnerable brain region relies on a distinct retromer core dedicated to endosomal recycling. Simoes et al.

description: Original western blot images used in the manuscript titled 'Alzheimer’s vulnerable brain region relies on a distinct retromer core dedicated to endosomal recycling'.