cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.15468/dl.q2gqwp
title: Occurrence Download

description: A dataset containing 341 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Bursera ovalifolia",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present"
 ]
}

 The dataset includes 341 records from 23 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0030222-251025141854904/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.17568637
title: High-Resolution(1km) Gridded Dataset of Premature Deaths Attributed to PM2.5 Exposure in China during 2000-2019

description: This file is a compressed NetCDF (.nc) dataset representing the mortality rates attributable to PM2.5 exposure for major diseases in China from 2000 to 2019.

File Type: NetCDF4Spatial Coverage: ChinaTemporal Coverage: 2000–2019 Spatial Resolution: 1 km × 1 km PM2.5 Sources: CHAP、ACAG、NASADisease Types:· Both IER and GEMM include the five major causes of death (5-COD: STR, IHD, COPD, LNC, LRI)· GEMM additionally includes NCD+LRI.Variable Naming Convention: {gender}_{age}_{disease}gender ∈ {m, f}: male, femaleage ∈ {25, 30, 35, …, 80}disease ∈ {STR, IHD, COPD, LNC, LRI, NCD+LRI}
DOI: 10.5281/zenodo.17395586
title: High-Resolution(1km) Gridded Dataset of Premature Deaths Attributed to PM2.5 Exposure in China during 2000-2019

description: This file is a compressed NetCDF (.nc) dataset representing the mortality rates attributable to PM2.5 exposure for major diseases in China from 2000 to 2019.

File Type: NetCDF4Spatial Coverage: ChinaTemporal Coverage: 2000–2019 Spatial Resolution: 1 km × 1 km PM2.5 Sources: CHAP、ACAG、NASADisease Types:· Both IER and GEMM include the five major causes of death (5-COD: STR, IHD, COPD, LNC, LRI)· GEMM additionally includes NCD+LRI.Variable Naming Convention: {gender}_{age}_{disease}gender ∈ {m, f}: male, femaleage ∈ {25, 30, 35, …, 80}disease ∈ {STR, IHD, COPD, LNC, LRI, NCD+LRI}
DOI: 10.15468/dl.x8rj6g
title: Occurrence Download

description: A dataset containing 1018 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON((131.70705 25.58557,117.35865 48.88398,94.06021 39.36573,84.68405 30.84191,100.87928 3.70779,122.04674 -4.81598,131.70705 25.58557))",
 "TaxonKey is Aralia chinensis"
 ]
}

 The dataset includes 1018 records from 26 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0030224-251025141854904/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.17596677
title: Submitted Galaxy Scores to the Gravitational Wave Treasure Map for event MS251113f Initial

description: Attached in a .json file is the ranked galaxy information within the contour region of the EM counterpart search associated with the gravitational wave event MS251113f Initial. A reference to these calculations can be found here: https://ui.adsabs.harvard.edu/abs/2017ApJ...848L..33A/abstract
DOI: 10.5281/zenodo.17596676
title: Submitted Galaxy Scores to the Gravitational Wave Treasure Map for event MS251113f Initial

description: Attached in a .json file is the ranked galaxy information within the contour region of the EM counterpart search associated with the gravitational wave event MS251113f Initial. A reference to these calculations can be found here: https://ui.adsabs.harvard.edu/abs/2017ApJ...848L..33A/abstract
DOI: 10.15468/dl.4skuhk
title: Occurrence Download

description: A dataset containing 79 species occurrences available in GBIF matching the query:
{
 "and" : [
 "OccurrenceStatus is Present",
 "TaxonKey is Nymphaea hastifolia"
 ]
}

 The dataset includes 79 records from 13 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0030225-251025141854904/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.17596675
title: Dataset4Moth-InspiredRobot
DOI: 10.5281/zenodo.17596674
title: Dataset4Moth-InspiredRobot
DOI: 10.15468/dl.myc487
title: Occurrence Download

description: A dataset containing 228355 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is one of (Amphitretidae, Bathypolypodidae, Eledonidae, Enteroctopodidae, Megaleledonidae, Octopodidae, Bolitaenidae, Idioctopodidae, Vitreledonella)"
 ]
}

 The dataset includes 228355 records from 548 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0030217-251025141854904/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.30607598
title: Gender and career progression in academia: European evidence

description: We study the career trajectories of university researchers in Europe, with an emphasis on the speed of career progression in academia, by gender. The analysis is based on data collected by the MORE project (Mobility Survey of the Higher Education Sector), a longitudinal database that gathers responses from over 10,000 university researchers across Europe using comparable definitions and metrics. We find that women have lower probabilities of advancement than their male counterparts, as found by the literature. However, conditional on advancing, women experience a faster career development than men at all career levels. The results suggest that higher salaries outside academia strengthen women's self-selection to stay in the research sector. Faster career progression among women is also influenced by international mobility but only for relatively short periods of time. These findings contribute enrich the general understanding of the dynamics shaping career progression among university researchers, particularly in relation to gender disparities.
DOI: 10.6084/m9.figshare.30607598.v1
title: Gender and career progression in academia: European evidence

description: We study the career trajectories of university researchers in Europe, with an emphasis on the speed of career progression in academia, by gender. The analysis is based on data collected by the MORE project (Mobility Survey of the Higher Education Sector), a longitudinal database that gathers responses from over 10,000 university researchers across Europe using comparable definitions and metrics. We find that women have lower probabilities of advancement than their male counterparts, as found by the literature. However, conditional on advancing, women experience a faster career development than men at all career levels. The results suggest that higher salaries outside academia strengthen women's self-selection to stay in the research sector. Faster career progression among women is also influenced by international mobility but only for relatively short periods of time. These findings contribute enrich the general understanding of the dynamics shaping career progression among university researchers, particularly in relation to gender disparities.
DOI: 10.34740/kaggle/dsv/13714684
title: Peer-to-Peer Boliviano (BOB) Exchange Data
DOI: 10.15468/dl.ghm4me
title: Occurrence Download

description: A dataset containing 5064 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON((174.39579 23.64662,144.84659 63.14021,99.38625 53.19576,85.17991 18.81639,134.90213 -0.22012,174.39579 23.64662))",
 "TaxonKey is Aralia elata"
 ]
}

 The dataset includes 5064 records from 132 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0030227-251025141854904/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.q65aj9
title: Occurrence Download

description: A dataset containing 60 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Bursera palaciosii",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present"
 ]
}

 The dataset includes 60 records from 13 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0030229-251025141854904/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.9ggcye
title: Occurrence Download

description: A dataset containing 50147 species occurrences available in GBIF matching the query:
{
 "and" : [
 "DatasetKey is one of (MHA Herbarium: collections of vascular plants, TULGU Herbarium: Tula Oblast collections of vascular plants, TUL Herbarium: Tula Oblast collections of vascular plants, IRKU Herbarium: collections of vascular plants, MAG Herbarium: collections of vascular plants, KUZ Herbarium: collections of vascular plants, KULPOL Herbarium: Tula Oblast collections of vascular plants, TKM Herbarium: Tula Oblast collections of vascular plants, Moscow University Herbarium (MW), KRSU Herbarium: collections of vascular plants, SMR Herbarium: collections of vascular plants)",
 "IsInCluster is true"
 ]
}

 The dataset includes 50147 records from 9 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0030226-251025141854904/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.95rycn
title: Occurrence Download

description: A dataset containing 72072947 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry MULTIPOLYGON(((83.50235 23.56362,88.50236 23.56362,93.50236 23.56362,93.50236 18.56362,98.50236 18.56362,103.50236 18.56362,103.50236 13.56362,103.50236 8.56362,103.50236 3.56362,103.50236 -1.43638,108.50236 -1.43638,113.50236 -1.43638,113.50236 3.56362,118.50236 3.56362,118.50236 8.56362,123.50236 8.56362,123.50236 13.56362,123.50236 18.56362,128.50236 18.56362,128.50236 23.56362,133.50236 23.56362,133.50236 28.56362,133.50236 33.56362,128.50236 33.56362,128.50236 38.56362,133.50236 38.56362,133.50236 43.56362,138.50236 43.56362,138.50236 48.56362,138.50236 53.56362,133.50236 53.56362,128.50236 53.56362,128.50236 58.56362,123.50236 58.56362,118.50236 58.56362,118.50236 53.56362,113.50236 53.56362,113.50236 48.56362,108.50236 48.56362,108.50236 43.56362,103.50236 43.56362,98.50236 43.56362,98.50236 48.56362,93.50236 48.56362,93.50236 53.56362,88.50236 53.56362,83.50235 53.56362,83.50235 48.56362,78.50235 48.56362,78.50235 43.56362,73.50235 43.56362,68.50235 43.56362,68.50235 38.56362,68.50235 33.56362,73.50235 33.56362,73.50235 28.56362,78.50235 28.56362,78.50235 23.56362,83.50235 23.56362)))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "LastInterpreted is greater than or equal to 2025-10-30",
 "OccurrenceStatus is Present"
 ]
}

 The dataset includes 72072947 records from 6826 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0030163-251025141854904/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.8117813
title: Different construction strategies affected on the physiology of <i>Pichia pastoris</i> strains highly expressed lipase by transcriptional analysis of key genes

description: We demonstrated previously that expression of <i>Rhizomucor miehei</i> lipase (RML) in <i>Pichia pastoris</i> could be significantly increased by addition of gene propeptide, optimized signal peptide codons and manipulation of gene dosage. In this study, effects of various strategies on the protein synthesis and secretion pathways were analyzed. Using nine strains previously constructed, we evaluated cell culture properties, enzymatic activities, and analyzed transcriptional levels of nine genes involved in protein synthesis and secretion pathways by qPCR. We observed that (i) Addition of propeptide decreased lipase folding stress by down-regulated four UPR-related genes. (ii) Signal peptide codons optimization had no effect on host with no change in the nine detected genes. (iii) Folding stress and limited transport capacity produced when <i>rml</i> gene dosage exceed 2. Different limiting factors on lipase expression in strains with different construction strategies were identified. This study provides a theoretical basis for further improving RML by transforming host.
DOI: 10.6084/m9.figshare.8117813.v1
title: Different construction strategies affected on the physiology of <i>Pichia pastoris</i> strains highly expressed lipase by transcriptional analysis of key genes

description: We demonstrated previously that expression of <i>Rhizomucor miehei</i> lipase (RML) in <i>Pichia pastoris</i> could be significantly increased by addition of gene propeptide, optimized signal peptide codons and manipulation of gene dosage. In this study, effects of various strategies on the protein synthesis and secretion pathways were analyzed. Using nine strains previously constructed, we evaluated cell culture properties, enzymatic activities, and analyzed transcriptional levels of nine genes involved in protein synthesis and secretion pathways by qPCR. We observed that (i) Addition of propeptide decreased lipase folding stress by down-regulated four UPR-related genes. (ii) Signal peptide codons optimization had no effect on host with no change in the nine detected genes. (iii) Folding stress and limited transport capacity produced when <i>rml</i> gene dosage exceed 2. Different limiting factors on lipase expression in strains with different construction strategies were identified. This study provides a theoretical basis for further improving RML by transforming host.
DOI: 10.6084/m9.figshare.10047119
title: Double deletion of <i>murA</i> and <i>murB</i> induced temperature sensitivity in <i>Corynebacterium glutamicum</i>

description: Currently, the mechanism of temperature-sensitive production of glutamate in <i>Corynebacterium glutamicum</i> has not been clarified. We first found the <i>murA</i> and <i>murB</i> genes were potentially related to temperature-sensitive secretion of glutamate, which were not existed in a temperature-sensitive mutant. When replenishing <i>murA</i> or/and <i>murB</i> in the mutant, the temperature sensitivity was weakened. While, their knockout in a wild-type strain resulted in temperature-sensitive secretion of glutamate. Peptidoglycan analysis showed that deletion of <i>murA</i> and <i>murB</i> decreased the peptidoglycan synthesis. Comparative metabolomics analysis suggested that the variation in cell wall structure resulted in decreased overall cellular metabolism but increased carbon flow to glutamate synthesis, which was a typical metabolism pattern in industrial temperature-sensitive producing strains. This study clarifies the mechanism between <i>murA</i> and <i>murB</i> deletion and the temperature-sensitive secretion of glutamate in <i>C. glutamcium</i>, and provides a reference for the metabolic engineering of cell wall to obtain increased bioproduction of chemicals.
DOI: 10.6084/m9.figshare.10047119.v1
title: Double deletion of <i>murA</i> and <i>murB</i> induced temperature sensitivity in <i>Corynebacterium glutamicum</i>

description: Currently, the mechanism of temperature-sensitive production of glutamate in <i>Corynebacterium glutamicum</i> has not been clarified. We first found the <i>murA</i> and <i>murB</i> genes were potentially related to temperature-sensitive secretion of glutamate, which were not existed in a temperature-sensitive mutant. When replenishing <i>murA</i> or/and <i>murB</i> in the mutant, the temperature sensitivity was weakened. While, their knockout in a wild-type strain resulted in temperature-sensitive secretion of glutamate. Peptidoglycan analysis showed that deletion of <i>murA</i> and <i>murB</i> decreased the peptidoglycan synthesis. Comparative metabolomics analysis suggested that the variation in cell wall structure resulted in decreased overall cellular metabolism but increased carbon flow to glutamate synthesis, which was a typical metabolism pattern in industrial temperature-sensitive producing strains. This study clarifies the mechanism between <i>murA</i> and <i>murB</i> deletion and the temperature-sensitive secretion of glutamate in <i>C. glutamcium</i>, and provides a reference for the metabolic engineering of cell wall to obtain increased bioproduction of chemicals.
DOI: 10.6084/m9.figshare.9778109
title: Expression of long non-coding RNA H19 predicts distant metastasis in minimally invasive follicular thyroid carcinoma

description: Downregulation of lncRNA H19 (H19) expression is associated with an unfavorable prognosis in some cancers. However, little was known as to whether there was an association between H19 and minimally invasive follicular thyroid carcinoma (MI-FTC). In our study, we used quantitative real-time polymerase chain reaction (qRT-PCR) to determine H19 expression in 186 patients with MI-FTC who underwent initial surgery. Of the 186 patients with MI-FTC, 21 patients show distant metastasis （M+）at the initial operation established the diagnosis of MI-FTC. Of the 165 patients who did not show distant metastasis at diagnosis during the follow-up period (≥10 years), 28 patients undergone M+ and 137 patients has no distant metastasis（M-）after the initial operation. Low H19 expression was associated with large tumor size, vascular invasion, and distant metastasis. Univariate analysis showed that gender (male), age (45 years or older), primary tumor size (4 cm or more), vascular invasion and H19 level (&lt;1.12) were significant prognostic factors related to postoperative distant metastases. Multivariate analysis showed that age, primary tumor size (4 cm or more) and vascular invasion was a significant prognostic factor for survival. Patients with low H19 expression showed a poorer outcome in MI-FTC patients. Receiver-operating characteristic (ROC) curve analysis demonstrated H19 could distinguish M+ from M- patientswith a value of area under the curve (AUC). Our findings suggest that H19 is a potential prognostic factor for evaluating prognosis and the metastatic potential of MI-FTC at an initial operation stage.
DOI: 10.6084/m9.figshare.9778109.v1
title: Expression of long non-coding RNA H19 predicts distant metastasis in minimally invasive follicular thyroid carcinoma

description: Downregulation of lncRNA H19 (H19) expression is associated with an unfavorable prognosis in some cancers. However, little was known as to whether there was an association between H19 and minimally invasive follicular thyroid carcinoma (MI-FTC). In our study, we used quantitative real-time polymerase chain reaction (qRT-PCR) to determine H19 expression in 186 patients with MI-FTC who underwent initial surgery. Of the 186 patients with MI-FTC, 21 patients show distant metastasis （M+）at the initial operation established the diagnosis of MI-FTC. Of the 165 patients who did not show distant metastasis at diagnosis during the follow-up period (≥10 years), 28 patients undergone M+ and 137 patients has no distant metastasis（M-）after the initial operation. Low H19 expression was associated with large tumor size, vascular invasion, and distant metastasis. Univariate analysis showed that gender (male), age (45 years or older), primary tumor size (4 cm or more), vascular invasion and H19 level (&lt;1.12) were significant prognostic factors related to postoperative distant metastases. Multivariate analysis showed that age, primary tumor size (4 cm or more) and vascular invasion was a significant prognostic factor for survival. Patients with low H19 expression showed a poorer outcome in MI-FTC patients. Receiver-operating characteristic (ROC) curve analysis demonstrated H19 could distinguish M+ from M- patientswith a value of area under the curve (AUC). Our findings suggest that H19 is a potential prognostic factor for evaluating prognosis and the metastatic potential of MI-FTC at an initial operation stage.
DOI: 10.6084/m9.figshare.8046440
title: Generation of a novel HEK293 luciferase reporter cell line by CRISPR/Cas9-mediated site-specific integration in the genome to explore the transcriptional regulation of the PGRN gene

description: Progranulin has multiple functions in several physiological and pathological processes, including embryonic development, wound repair, tumorigenesis, inflammation and neurodegeneration. To investigate the transcriptional regulation of the PGRN gene, a luciferase knock-in reporter system was established in HEK293 cells by integrating luciferase gene in the genome controlled by the endogenous PGRN promoter using CRISPR/Cas9. PCR results demonstrated the site-specific integration of the exogenous luciferase gene into the genome. To validate the novel luciferase knock-in system, a CRISPR/Cas9 transcription activation/repression system for the PGRN gene was constructed and applied to the knock-in system. In addition, phorbol ester (phorbol 12-myristate, 13-acetate), previously reported as activating the expression of PGRN, was applied to the system. The results indicated that luciferase activity was directly correlated with the activity of the PGRN endogenous promoter. This novel system will be a useful tool for investigating the transcriptional regulation of PGRN, and it has great potential in screening the drugs targeting PGRN.
DOI: 10.6084/m9.figshare.8046440.v1
title: Generation of a novel HEK293 luciferase reporter cell line by CRISPR/Cas9-mediated site-specific integration in the genome to explore the transcriptional regulation of the PGRN gene

description: Progranulin has multiple functions in several physiological and pathological processes, including embryonic development, wound repair, tumorigenesis, inflammation and neurodegeneration. To investigate the transcriptional regulation of the PGRN gene, a luciferase knock-in reporter system was established in HEK293 cells by integrating luciferase gene in the genome controlled by the endogenous PGRN promoter using CRISPR/Cas9. PCR results demonstrated the site-specific integration of the exogenous luciferase gene into the genome. To validate the novel luciferase knock-in system, a CRISPR/Cas9 transcription activation/repression system for the PGRN gene was constructed and applied to the knock-in system. In addition, phorbol ester (phorbol 12-myristate, 13-acetate), previously reported as activating the expression of PGRN, was applied to the system. The results indicated that luciferase activity was directly correlated with the activity of the PGRN endogenous promoter. This novel system will be a useful tool for investigating the transcriptional regulation of PGRN, and it has great potential in screening the drugs targeting PGRN.
DOI: 10.6084/m9.figshare.8203061
title: Vaccinia virus injected human tumors: oncolytic virus efficiency predicted by antigen profiling analysis fitted boolean models

description: Virotherapy on the basis of oncolytic vaccinia virus (VACV) strains is a promising approach for cancer therapy. Recently, we showed that the oncolytic vaccinia virus GLV-1h68 has a therapeutic potential in treating human prostate and hepatocellular carcinomas in xenografted mice. In this study, we describe the use of dynamic boolean modeling for tumor growth prediction of vaccinia virus-injected human tumors. Antigen profiling data of vaccinia virus GLV-1h68-injected human xenografted mice were obtained, analyzed and used to calculate differences in the tumor growth signaling network by tumor type and gender. Our model combines networks for apoptosis, MAPK, p53, WNT, Hedgehog, the T-killer cell mediated cell death, Interferon and Interleukin signaling networks. The <i>in silico</i> findings conform very well with <i>in vivo</i> findings of tumor growth. Similar to a previously published analysis of vaccinia virus-injected canine tumors, we were able to confirm the suitability of our boolean modeling for prediction of human tumor growth after virus infection in the current study as well. In summary, these findings indicate that our boolean models could be a useful tool for testing of the efficacy of VACV-mediated cancer therapy already before its use in human patients.