DOI: 10.18150/gxfgek
title: Structural, compositional, and bioactive assessment of Ti3C2Tx MXene-modified alginate, chitosan, elastin, keratin, and collagen hydrogels

description: This database contains raw data from a comprehensive study investigating the potential of Ti3C2Tx MXene in enhancing the bioactive properties of organic-based hydrogels composed of alginate, chitosan, elastin, keratin, and collagen. The dataset includes detailed characterization of the parental MAX and synthesized MXene, covering morphology, structure, elemental and phase composition, optical properties, and chemical composition. Additionally, data on the incorporation of MXene into hydrogel matrices and its impact on structural modifications are provided. The bioactive studies in this dataset focus on biocompatibility, ROS scavenging activity, and the biostatic and biocidal effects against E. coli and S. aureus, highlighting the role of MXene in modulating these properties.1. Characterization of Ti3C2Tx MXene.zip: It includes extensive characterization data for Ti3C2Tx MXene, a two-dimensional transition metal carbide known for its unique electrical, mechanical, and chemical properties. Various analytical techniques have been used to examine the material in both dispersion and powder forms, comparing with parental MAX phase. Dynamic light scattering (DLS) provides insights into the particle size distribution of MXene nanosheets in solution. Energy dispersive spectroscopy (EDS) confirms the elemental composition, highlighting the presence of titanium, carbon, and surface termination groups. Fourier transform infrared spectroscopy (FTIR) identifies functional groups and surface chemistry modifications. Zeta potential measurements assess the colloidal stability and surface charge of Ti3C2Tx MXene in aqueous dispersions. Raman spectroscopy investigates the vibrational modes and layered structure. Scanning electron microscopy (SEM) provides high-resolution images of MXene morphology and nanosheet arrangement. Dynamic particle analysis (DPA) examines the motion and size distribution of dispersed MXene nanosheets. UV-Visible spectroscopy (UV-Vis) measures the optical absorption properties, helping evaluate dispersion quality and stability. X-ray diffraction (XRD) confirms the crystallographic structure and phase purity of Ti3C2Tx MXene. Tyndall effect analysis demonstrates the light-scattering behavior of the colloidal dispersion, further validating its stability. This dataset is useful for researchers studying nanomaterials, MXenes, colloidal chemistry, and material science applications, offering a comprehensive set of experimental data for further investigation.2. SEM images of hydrogels.zip: This dataset includes scanning electron microscope (SEM) images of both pristine hydrogel matrices and hydrogels modified with Ti3C2Tx MXene. The SEM images offer detailed high-resolution visual insights into the surface morphology, structural features, and any changes introduced to the hydrogels by the MXene modification. Researchers can use this data to analyze the impact of Ti3C2Tx MXene on the hydrogel’s microstructure and evaluate its potential applications in areas such as material science, biomedical engineering, and nanocomposite development.3. Studies_on_porosity_of_hydrogels_modified_with Ti3C2Tx_MXene.zip: This archive contains detailed porosity analysis data for hydrogels modified with Ti3C2Tx MXene, derived from Scanning Electron Microscopy (SEM) imaging. SEM images were subjected to quantitative image analysis using ImageJ software (NIH, Bethesda, MD, USA) to assess microstructural parameters. Key evaluated metrics include average pore size, pore diameter, sphericity factor, maximum and minimum Feret diameters, and Feret diameter ratio. These porosity assessments provide critical insight into how Ti₃C₂Tₓ MXene incorporation influences hydrogel morphology, potentially affecting their performance in applications such as drug delivery, tissue engineering, and advanced biomaterials development.4. Characterization of hydrogels modified with Ti3C2Tx MXene.zip: This archive contains comprehensive characterization data for hydrogel matrices modified with Ti3C2Tx MXene, including results from Fourier Transform Infrared Spectroscopy (FTIR), X-ray Fluorescence Spectroscopy (XRF), and microscopic analyses. FTIR spectroscopy identifies changes in functional groups and chemical bonding interactions between MXene and the organic hydrogel components. XRF spectroscopy: Provides elemental composition data, confirming the distribution and integration of Ti3C2Tx MXene within the hydrogel structure. Microscopic Observations (optical and SEM) reveals morphological alterations, including variations in porosity, surface roughness, and MXene dispersion throughout the hydrogel network. These analyses offer valuable insights into how MXene modification influences the structural, chemical, and bioactive properties of hydrogels, paving the way for their potential applications in biomedical and material science fields.5. Rheological_studies_on_hydrogels_modified_with_Ti3C2Tx_MXene.zip: This archive contains rheological characterization data for hydrogel matrices modified with Ti3C2Tx MXene, obtained through oscillatory rheological measurements. Experiments were performed using rheometer with parallel plate geometry. Key viscoelastic parameters recorded include storage modulus (G') and loss modulus (G''), providing insights into the elastic and viscous behavior of the hydrogels. Complex viscosity (η*) was also calculated to further evaluate the material's flow characteristics. These rheological profiles help elucidate the influence of Ti3C2Tx MXene incorporation on the mechanical stability and dynamic response of hydrogel systems, contributing to their optimization for biomedical and soft material applications.6. Evaluation of bioactivity with OD610.zip: This dataset contains the results of antibacterial property studies conducted on hydrogel matrices modified with Ti3C2Tx MXene. The bioactivity of the hydrogels was evaluated using optical density (OD) measurements at 610 nm. These results provide insights into the antibacterial effectiveness of the modified hydrogels, useful for research in fields such as biomedical applications, material science, and the development of antimicrobial nanocomposites.7. Evaluation of bioactivity with CFU.zip: This dataset contains the results of antibacterial property studies carried out on hydrogel matrices modified with Ti3C2Tx MXene. The antibacterial properties were evaluated through agar plate culture, with the results presented as colony-forming units (CFU). These data provide valuable information on the antimicrobial effectiveness of the modified hydrogels, which can be used in research related to biomedical applications, antimicrobial material development, and nanocomposite technologies.8. Evaluation of bioactivity with ROS.zip: This dataset presents results from studies evaluating the reactive oxygen species (ROS) scavenging properties of hydrogel matrices modified with Ti3C2Tx MXene. The bioactivity was assessed using fluorescent probes, and the results are presented as fluorescence intensity, which corresponds to the scavenging activity of the materials in terms of ROS reduction. ROS scavenging is an important property, especially in biomedical applications, as excessive ROS levels are linked to oxidative stress and various diseases. The data demonstrate the potential of Ti3C2Tx MXene-modified hydrogels to neutralize harmful ROS, making them valuable for applications like wound healing, tissue engineering, and the development of antioxidant materials.