Rebound symptoms after Paxlovid started May 22nd Worse symptoms then during the actual week of having Covid. Had tested on PCR, but negative on home test. Now testing positive on home antigen test.; This spontaneous case was reported by a consumer and describes the occurrence of COVID-19 (Rebound symptoms after Paxlovid started May 22nd Worse symptoms then during the actual week of having Covid. Had tested on PCR, but negative on home test. Now testing positive on home antigen test.) in a 76-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination.     The patient's past medical history included Stent insertion NOS. Concomitant products included ATORVASTATIN and METOPROLOL for an unknown indication.    On an unknown date, the patient received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 22-May-2022, the patient experienced COVID-19 (Rebound symptoms after Paxlovid started May 22nd Worse symptoms then during the actual week of having Covid. Had tested on PCR, but negative on home test. Now testing positive on home antigen test.). The patient was treated with NIRMATRELVIR, RITONAVIR (PAXLOVID) from 09-May-2022 to 13-May-2022 for COVID-19, at an unspecified dose and frequency. At the time of the report, COVID-19 (Rebound symptoms after Paxlovid started May 22nd Worse symptoms then during the actual week of having Covid. Had tested on PCR, but negative on home test. Now testing positive on home antigen test.) outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On 22-May-2022, SARS-CoV-2 test: positive (Positive) positive on home antigen test. On an unknown date, SARS-CoV-2 test: negative (Negative) negative on home test.         The patient was taking any other medications/products within 2 weeks of starting COVID-19 treatment. The patient previously received a COVID-19 Vaccine.  Company Comment: This spontaneous case concerns a 76 year-old female patient, with no relevant medical history reported, who experienced the unexpected, non-serious Adverse Event of Special Interest of COVID-19,  which occurred unknown days after a dose of mRNA-1273 vaccine administration, given as the third dose. No information regarding previous doses of COVID-19 vaccine. Patient reported rebound symptoms after Paxlovid was started on May 22nd, described as worse symptoms then during the actual week of having COVID-19. Patient previously tested on PCR, but negative on home test, but now testing positive on home antigen test. The ongoing COVID-19 pandemic could be a confounder for the event. The benefit-risk relationship of mRNA-1273 vaccine is not affected by this report.; Sender's Comments: This spontaneous case concerns a 76 year-old female patient, with no medical history reported, who experienced the unexpected, non-serious Adverse Event of Special Interest of COVID-19,  which occurred unknown days after a dose of mRNA-1273 vaccine administration, given as the third dose. No information regarding previous doses of COVID-19 vaccine. Patient reported rebound symptoms after Paxlovid was started on May 22nd, described as worse symptoms then during the actual week of having COVID-19. Patient previously tested on PCR, but negative on home test, but now testing positive on home antigen test. The ongoing COVID-19 pandemic could be a confounder for the event. The benefit-risk relationship of mRNA-1273 vaccine is not affected by this report.