Hepatic Impairment; liver enzyme elevation; nausea; vomiting; food intolerance; have lost more than 30 pounds; no quality of life; severely malnourished; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP). The reporter is the patient.  A 38 year-old female patient (not pregnant) received BNT162B2 (PFIZER-BIONTECH COVID-19 MRNA VACCINE), administered in arm left, administration date 2021 (Lot number: EW0175) at the age of 38 years as dose 2, single for COVID-19 immunisation. Relevant medical history included: "Blood clotting disorder" (unspecified if ongoing); "fibromyalgia" (unspecified if ongoing); "allergies to shellfish" (unspecified if ongoing). Prior to the vaccination, the patient was not diagnosed with COVID-19. Concomitant medication(s) included: dabigatran etexilate mesilate (PRADAXA) and unspecified multivitamins. Past drug history included: Erythromycin base, reaction(s): "allergies"; Doxycycline, reaction(s): "allergies"; Amoxicillin, reaction(s): "allergies"; cefuroxime axetil (CEFTIN), reaction(s): "allergies"; apixaban (ELIQUIS), reaction(s): "allergies"; Ciprofloxacin, reaction(s): "allergies". Vaccination history included: BNT162B2 (Dose 1; Lot number: ER8731 in the left arm), administration date: 2021, for COVID-19 immunization. The patient did not receive any other vaccines within four weeks prior to the vaccination. The following information was reported: HEPATIC FUNCTION ABNORMAL (life threatening) with onset 15Apr2021, outcome "not recovered", described as "Hepatic Impairment"; HEPATIC ENZYME INCREASED (life threatening) with onset 15Apr2021, outcome "not recovered", described as "liver enzyme elevation"; NAUSEA (life threatening) with onset 15Apr2021, outcome "not recovered", described as "nausea"; VOMITING (life threatening) with onset 15Apr2021, outcome "not recovered", described as "vomiting"; FOOD INTOLERANCE (life threatening) with onset 15Apr2021, outcome "not recovered", described as "food intolerance"; WEIGHT DECREASED (life threatening) with onset 15Apr2021, outcome "not recovered", described as "have lost more than 30 pounds"; QUALITY OF LIFE DECREASED (life threatening) with onset 15Apr2021, outcome "not recovered", described as "no quality of life"; MALNUTRITION (life threatening) with onset 15Apr2021, outcome "not recovered", described as "severely malnourished". The events "hepatic impairment", "liver enzyme elevation", "nausea", "vomiting", "food intolerance", "have lost more than 30 pounds", "no quality of life" and "severely malnourished" were evaluated at the physician office visit and emergency room visit. The clinical course was reported as follows: The patient experienced hepatic Impairment (liver enzyme elevation) with nausea, vomiting, and food intolerance. Symptoms were still on-going. She had lost more than 30 pounds and have had no quality of life since Apr2021. The patient became severely malnourished from not being able to eat without vomiting. All imaging and other tests ruled out all other possible causes for hepatic impairment. Treatment included integrative medicine intravenous (IV) homeopathic drip therapies. The patient underwent the following laboratory tests and procedures: imaging procedure: (2021) ruled out all other possible, notes: causes for hepatic impairment; investigation: (2021) ruled out all other possible, notes: causes for hepatic impairment; liver function test: (2021) elevation; sars-cov-2 test: (27Sep2021) negative, notes: Nasal Swab; weight: (2021) lost more than 30, notes: pounds. Therapeutic measures were taken as a result of hepatic function abnormal, hepatic enzyme increased, nausea, vomiting, food intolerance, weight decreased, quality of life decreased, malnutrition.