Rash/ Herald's Patch; Rash/ Herald's Patch; redness around the injection site; This is a spontaneous report from a Pfizer sponsored program. A contactable consumer (patient) reported that a 54-years-old female patient received first dose of BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, formulation: Solution for injection, lot number: EN6207, patient was 54-year-old at the time of vaccination), via an unspecified route of administration, administered in Arm Left on 11Mar2021 as single dose for covid-19 immunisation. Medical history included Sinus issues from 1999 to an unknown date, sickle cell trait diagnosed when she was a baby. Carried on her mother's side, teno Achilles transplant in the past she has had pain in her life, skin graft. There were no concomitant medications. Reported that patient had a condition of Herald Patch (a red patch that shows up and goes away and then after that gets symptoms of a rash), she would like to know if this has been reported before. The caller explains that a Herald's Patch usually occurs once in your lifetime and they occur on your upper body usually on your neck. It is a little patch, and it looks like a tattoo, this doesn't hurt, itch, or sting but its an indication that something is coming. When the Herald's Patch disappears that's when you start itching. It's only supposed to occur once in your lifetime and the caller has had 3-4 in her lifetime. The caller's Herald's Patch usually happens at the change of seasons going into spring. Herald's Patches usually go along with pityriasis rosacea, they can be connected to different types of itching and things like that, but that is part of what this is. A Herald's Patch can be triggered by a viral infection or from being sexually active. The caller is not sexually active and was not sexually active when she got her first Herald's Patch when she was 14. The caller got a Herald's Patch when she was 14 and got it on her neck and it went away before she went to the doctor. The caller took some cream, and it took 2-3 weeks to go away. This hasn't happened for over 20 years. When the caller got the first dose, she got the redness around the injection site, she thought it was hypersensitivity to the Band-Aid. The caller took a shower the next day and she took the band aid off and saw a red kind of rash thing and she thought it was from the band aid and never connected the two. The caller later realized this was a Herald's Patch. So, when this thing happened on the caller's arm, she knew that's what it was because if it was from the Band-Aid it should have gone away in a couple of days and it didn't. When the caller got the second dose, the day after that the Harold's Patch disappeared. Then the rash was gone like it was never there. The rash went away and then the itching and burning started. She adds that in the past she has had pain in her life. She had an Achilles transplant. that required skin grafts and had to give a wound vac to harvest the area. They took skin from left forearm and you could see clear to the bone. She has never experienced anything where she could not close her hands or walk. It would have been good if the nurses signed or initialled the cards. On 11Mar2021, the patient experienced rash/ herald's patch, redness around the injection site. Reporter seriousness for First dose Rash/ Herald's Patch was Unspecified and related with Pfizer covid vaccine first dose. The patient underwent lab tests and procedures which included blood creatine phosphokinase resulted as elevated on 08Apr2021, 13Apr2021 and 11May2021. It was reported that they took the caller's blood and her CK level was way off the charts when she was in the emergency room. The caller did a video visit the next day with her primary care provider and they wanted the caller to come in and do another blood test. The doctor explained that some other patients who had gotten Moderna or Pfizer covid vaccine, it didn't matter, were experiencing some of what the caller has been experiencing. The caller's doctor has no doubt that the caller had a reaction to the vaccine. The caller's CK has come down and not in normal range not even now. The caller's doctor is going to monitor the caller for a while, she feels way better. 12Jun2021 is the next blood level test, her CK level still isn't within a normal range. The outcome of event (rash/ herald's patch) was recovered on 02Apr2021 and the outcome of event (redness around the injection site) was recovered on 01Apr2021.  Information on Lot/Batch number was available. Additional information has been requested