rash/delayed rash/only on her extremities/itches so bad; When it was there was red; Chills; flu like reaction; This is a spontaneous report from a contactable nurse (patient). A 74-year-old female patient received the second dose of BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, lot number: EW0173 and expiration date not provided), via an unspecified route of administration, on 11May2021 (at the age of 74-year-old), at single dose, for COVID-19 immunization. Medical history included thyroid condition. Concomitant medication included levothyroxine taken for thyroid condition. The patient previously took first dose of BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, lot number: EW0153 and expiration date not provided), via an unspecified route of administration, on 11Apr2021 (at the age of 74-year-old), at single dose, for COVID-19 immunization. On 17May2021 the patient experienced rash/delayed rash/only on her extremities/itches so bad. On unknown date in May2021 the patient experienced chills, flu like reaction. Patient originally started having flu like reactions the first couple of days, and took paracetamol (TYLENOL) or acetylsalicylic acid (ASPIRIN). Those symptoms went away. She mainly had chills. The chills and flu like symptoms only lasted a couple of days. She probably didn't get that reaction until the next day or day after, so the 12May2021, or the 13May2021. On 17May2021 patient developed a rash comes and goes every 4-6 hours, when it goes away can't tell she ever even had a rash. Patient asked if any reports of delayed rash and how long it may last for. She was seeing her doctor on 09Jun2021 for this issue. She started getting a rash that was fleeting. It comes and goes. It is like an immune reaction/ antigen antibody reaction that comes every 4-6 hours. She started using Cortisone cream when really angry and itchy and it calmed it down. "Yesterday", she started using diphenhydramine hydrochloride (BENADRYL). She was taking 25mg, she had taken 3, but she was trying not to take it too often. Patient had improved, today on scale, 3-4 out of 10. With the diphenhydramine hydrochloride, the reaction was more of a milder itch. The rash resembles measles or rosacea. It was only on her extremities (arm and legs). It was not on her torso or face or hands. It was very itchy though, and only stayed for an hour or so. Before she took the cortisone cream the rash was very angry. It itched a lot before the cortisone cream. It goes away, and she couldn't even see it. There were no scars. When it was there was red and very itchy. It was not like hives. Like with a hive if you scratch it, it would make a line of a hive. She had no problems with breathing. The rash seemed to spread more and more. First it was on her wrist and forearms, and then it seems to be larger each time. Instead of just being on the bottom of her wrist, It goes all the way up to her elbow. It started on her ankle too, and then went up to thighs and calves. Now it was all over her arms and legs. It was reported patient was involved in giving the H1N1 inoculation. When the patient gave H1N1 vaccines, the medicine was already in the syringe. Therapeutic measures were taken as a result of rash/delayed rash/only on her extremities/itches so bad and flu like reaction. The outcome of the event " rash/delayed rash/only on her extremities/itches so bad " was not recovered (reported as worsened); of "chills/ flu like reaction" was recovered in May2021.