felt sick; swollen  face; hurting throat; whole body was ice cold and painful; thought was an infection; her left chest was red and itching  so bad; joint pain for more than 10 days; mild headache; Rash, heart rate irregular, taste disorder, sneezing, dyspnoea, chest tightness, hypoaesthesia, and chills; Itching; This spontaneous case was reported by a consumer and describes the occurrence of ILLNESS (felt sick), SWELLING FACE (swollen  face), OROPHARYNGEAL PAIN (hurting throat), FEELING COLD (whole body was ice cold and painful) and SKIN INFECTION (thought was an infection) in a 51-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 008C21A and 023C21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     No Medical History information was reported.   On 26-Jun-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 23-Jul-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 27-Jun-2021, the patient experienced PRURITUS (Itching), RASH (rash), HYPOAESTHESIA (numbness), TASTE DISORDER (unsual taste), CHEST DISCOMFORT (chest tightness), DYSPNOEA (difficulty breathing) and SNEEZING (sneezing/ running nose). On 27-Jun-2021 at 2:00 AM, the patient experienced CHILLS (chills) and HEART RATE IRREGULAR (irregular heart rate). On 24-Jul-2021, the patient experienced ILLNESS (felt sick), SWELLING FACE (swollen  face), OROPHARYNGEAL PAIN (hurting throat), FEELING COLD (whole body was ice cold and painful), SKIN INFECTION (thought was an infection), ERYTHEMA (her left chest was red and itching  so bad), ARTHRALGIA (joint pain for more than 10 days) and HEADACHE (mild headache). The patient was treated with HYDROGEN PEROXIDE for Redness and Itchy, at a dose of 1 dosage form; IBUPROFEN for Adverse event, at a dose of 400 milligram and Manual therapy (warm medical electric blanket) for Feeling cold. On 30-Jun-2021, PRURITUS (Itching), RASH (rash), HYPOAESTHESIA (numbness), TASTE DISORDER (unsual taste), CHEST DISCOMFORT (chest tightness), DYSPNOEA (difficulty breathing) and SNEEZING (sneezing/ running nose) had resolved. On 30-Jun-2021 at 1:00 AM, CHILLS (chills) and HEART RATE IRREGULAR (irregular heart rate) had resolved. At the time of the report, ILLNESS (felt sick), SWELLING FACE (swollen  face), OROPHARYNGEAL PAIN (hurting throat), FEELING COLD (whole body was ice cold and painful), SKIN INFECTION (thought was an infection), ARTHRALGIA (joint pain for more than 10 days) and HEADACHE (mild headache) had resolved and ERYTHEMA (her left chest was red and itching  so bad) had not resolved.            No concomitant medications were provided.   Most recent FOLLOW-UP information incorporated above includes: On 21-Sep-2021: Follow-up received on 21-Sep-2021 is Significant follow up. New events were added.; Sender's Comments: This case concerns a 51 year old female with no relevant medical history who experienced the listed non-serious AESI of Anaphylactic reaction four days after the second dose of Moderna COVID-19 vaccine. Other non-serious events occurred one day after the second dose. Re-challenge is not applicable as this was the second dose. The event is consistent with the current understanding of the mechanism of action of the vaccine. Benefit-risk relationship of Moderna COVID-19 vaccine is not affect by this report.