Her energy level never return since then, she can feel the air that sucks out of her chest and it felt something hit in the middle of her chest; Severe arthritis; Ache was so bad/felt a lot of pain that crosses on her lower back; Ache was so bad, she cannot get out of her bed; Had a temperature of 102 degree Fahrenheit; The fatigue usually lasts for 4-5 hours; Breath was being taken away and she stood for a second if that happens; Energy level do not return/never felt the energy that she had before; This spontaneous case was reported by a consumer and describes the occurrence of CHEST DISCOMFORT (Her energy level never return since then, she can feel the air that sucks out of her chest and it felt something hit in the middle of her chest), ARTHRITIS (Severe arthritis), PAIN (Ache was so bad/felt a lot of pain that crosses on her lower back), DYSPNOEA (Breath was being taken away and she stood for a second if that happens) and ASTHENIA (Energy level do not return/never felt the energy that she had before) in an 83-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 001A21A, 030M20A and 034F21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     Concurrent medical conditions included Penicillin allergy and Neoplasm (Letrozole 2.5mg once daily (antineoplastic)). Concomitant products included LETROZOLE for Cancer (NOS).   On 16-Feb-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 17-Mar-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 08-Dec-2021, received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 17-Mar-2021, the patient experienced ARTHRITIS (Severe arthritis), PAIN (Ache was so bad/felt a lot of pain that crosses on her lower back), MOBILITY DECREASED (Ache was so bad, she cannot get out of her bed) and PYREXIA (Had a temperature of 102 degree Fahrenheit). In 2021, the patient experienced DYSPNOEA (Breath was being taken away and she stood for a second if that happens), ASTHENIA (Energy level do not return/never felt the energy that she had before) and FATIGUE (The fatigue usually lasts for 4-5 hours). On an unknown date, the patient experienced CHEST DISCOMFORT (Her energy level never return since then, she can feel the air that sucks out of her chest and it felt something hit in the middle of her chest). At the time of the report, CHEST DISCOMFORT (Her energy level never return since then, she can feel the air that sucks out of her chest and it felt something hit in the middle of her chest), ARTHRITIS (Severe arthritis), PAIN (Ache was so bad/felt a lot of pain that crosses on her lower back), DYSPNOEA (Breath was being taken away and she stood for a second if that happens), ASTHENIA (Energy level do not return/never felt the energy that she had before), MOBILITY DECREASED (Ache was so bad, she cannot get out of her bed), FATIGUE (The fatigue usually lasts for 4-5 hours) and PYREXIA (Had a temperature of 102 degree Fahrenheit) outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On 17-Mar-2021, Body temperature: 102 degree fahrenheit (High) 102 degree Fahrenheit.         On 17-Mar-2021, the patient had a temperature of 102-degree Fahrenheit, the ache was bad, she cannot get out of her bed, had a severe arthritis, felt a lot of pain that crossed on her lower back. Her energy level never returned since then, she felt the air that sucked out of her chest and it felt something hit in the middle of her chest. The fatigue usually lasts for 4-5 hours and she never felt the energy that she had before. Her breath was being taken away and she stood for a second if that happens.  The patient had her first dose of Moderna Covid-19 vaccine with no adverse events.  The patient had no treatments taken on the adverse events experienced.  Patient was taking Letrozole 2.5mg once daily and was last taken 26-Jan-2022.  Company comment: This is a spontaneous case concerning a 83-year-old female patient with medical history of neoplasm, who experienced the non-serious AESI event of arthritis and other non-serious events. The event pneumothorax occurred on an unknown date after the booster dose of mRNA-1273 and arthritis occurred the same day after the booster dose. The mentioned medical history remains a confounder. The benefit-risk relationship of mRNA-1273 vaccine is not affected by this report.   This case was linked to MOD-2022-463218 (Patient Link).; Sender's Comments: This is a spontaneous case concerning a 83-year-old female patient with medical history of neoplasm, who experienced the non-serious AESI event of arthritis and other non-serious events. The event pneumothorax occurred on an unknown date after the booster dose of mRNA-1273 and arthritis occurred the same day after the booster dose. The mentioned medical history remains a confounder. The benefit-risk relationship of mRNA-1273 vaccine is not affected by this report.