Having nervousness this morning, doesn't usually have that; Her blood pressure has been running elevated since after the vaccine/156/78 with a 73 and she took it again a little bit later, it was 155/88 with an 84; This is a spontaneous report from a contactable consumer (patient). A 77-year-old female patient received bnt162b2 (BNT162B2, Lot Number: 301308A), dose 1 via an unspecified route of administration, administered in left arm on 14Sep2021 10:15 (at the age of 77-year-old) as dose 1, single for COVID-19 immunization.  Medical history included stroke, glaucoma, eye surgery (implant in her eye), eye was swelling, and retina problems. Concomitant medication included dorzolamide hcl taken for glaucoma and has surgery (eye surgery) from Aug2021 and ongoing. She had to change to this medication because she was having a reaction to one of the other medications. The patient declines to provide other medication product information that she was having a reaction to, states it was just some medication that she had been on a long time ago. She had eye surgery and her eye was swelling a little bit and so the doctor changed her over to Dorzolamide HCL. Historical vaccine included flu shots and she had the lung thing. Prior vaccinations the patient does not have any other vaccinations within four weeks prior to the first administration date of the suspect vaccine. The patient received the first dose on 14Sep2021, and her blood pressure has been running elevated since after the vaccine on 14Sep2021 at 19:16. She is taking some eye drops that actually run her blood pressure down called Dorzolamide 2%. The patient stated before this her pressure was running 128,118, and 119 on unspecified date and then she had the shot and she got home and so her blood pressure was like 120/59 and 79, that was about 3:33PM on 14Sep2021, she did her eye, which is a medicine, it's called Dorzolamide HCL 2% eye drops, and that always runs her pressure down, but when she went to take her pressure at 7:16PM,  it was 156/78 with a 73 and she took it again a little bit later, it was 155/88 with an 84, and so she went ahead and took her blood pressure medicine and went to bed. She got up this morning (15Sep2021) and it was 134/68 with an 80, which she's been running 120/68 with a 66, so she just now took it again at 12:31PM today because she did her eyes this morning and did her blood pressure medicine, this morning, about 0900, and she took it at 12:31PM and now she has 154/71 with a 79. She would like to know if the medicine is causing this or if her eye medicine, she has glaucoma, and the medicines for that, she's had surgery, she also has an implant in her eye because of retina problems and she doesn't know if she is having reaction because of the shot or not. She just needs to know because she's had a stroke, and to have 150 blood pressure is scary. The patient would like to know if there have been reports of elevated blood pressure after the shot. She has had a stroke in the past and is scared with her blood pressure being high again. She also doesn't know if maybe some of her medicines were causing a problem or reaction with the vaccine. The patient would like to know if Dorzolamide could be causing a potential interaction with the vaccine. She just had the shot last night, then she kept noticing she was kind of having nervousness the morning of 15Sep2021 and she usually doesn't do that, then she noticed she just now took it, so she wanted to make sure. She stated her blood pressure has been running real low and she hasn't had a problem until they did that yesterday and it scares her. Therapeutic measure was taken as a result of the event blood pressure has been running elevated which included blood pressure medicine. The outcome of the event blood pressure has been running elevated was not recovered. The outcome of the remaining event was unknown.