lose her hair; had low iron; feeling groggy; Her daughter said she was tired/ tiredness; She missed her period cycle for over about a week now/ She missed her cycle; sore arm from the vaccine; She was so pale; very sick; fever; Fell asleep for a day and a half/ / She slept for 2 days; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP) from medical information team for a Pfizer sponsored program. The reporter is the parent. Other Case identifier(s): PFIZER INC-202101275219 (Pfizer),  PFIZER INC-202200143754 (Pfizer).  A 23 year-old female patient (not pregnant) received bnt162b2 (BNT162B2), administered in arm left, administration date 03Sep2021 (Lot number: F00809) at the age of 23 years as dose 1, single for covid-19 immunisation. Relevant medical history included: "allergic to leather" (unspecified if ongoing), notes: Allergic to leather; "allergic when she took the medication" (unspecified if ongoing), notes: She was allergic when she took the medication (unspecified medication) in the past.; "lupus" (unspecified if ongoing), notes: history of lupus (about 2-3 years ago); "acne" (unspecified if ongoing); "nodules on elbows" (unspecified if ongoing); "pain in arms that spread to whole body" (unspecified if ongoing); "depressed" (unspecified if ongoing), notes: She is still depressed and is losing her hair due to the depression; "losing her hair" (unspecified if ongoing), notes: She is taking Biotin for hair loss; "itchy rash" (unspecified if ongoing), notes: She used Calamine lotion to stop the itching; "blisters all over her chest and back" (unspecified if ongoing). There were no concomitant medications. Past drug history included: Minocycline for acne, reaction(s): "drug-induced lupus", notes: Was on Minocycline for a whole year; Minocycline, reaction(s): "fingers and elbows were blowing up", notes: Was on Minocycline for a whole year; Minocycline, reaction(s): "cannot even walk", notes: Was on Minocycline for a whole year; Minocycline, reaction(s): "nodules", notes: Was on Minocycline for a whole year; Minocycline, reaction(s): "allergic to minocycline"; Etodolac, reaction(s): "Allergy", notes: allergic to rotodulac (possibly ETODOLAC?); Prednisone, notes: was on prednisone for 2 years. The following information was reported: SOMNOLENCE (non-serious) with onset 2021, outcome "unknown", described as "Fell asleep for a day and a half/ / She slept for 2 days"; FATIGUE (non-serious) with onset Sep2021, outcome "unknown", described as "Her daughter said she was tired/ tiredness"; MENSTRUAL DISORDER (non-serious) with onset Sep2021, outcome "unknown", described as "She missed her period cycle for over about a week now/ She missed her cycle"; PAIN IN EXTREMITY (non-serious) with onset 2021, outcome "unknown", described as "sore arm from the vaccine"; PALLOR (non-serious) with onset 2021, outcome "unknown", described as "She was so pale"; ILLNESS (non-serious) with onset 2021, outcome "unknown", described as "very sick"; SOMNOLENCE (non-serious) with onset Sep2021, outcome "unknown", described as "feeling groggy"; PYREXIA (non-serious) with onset 2021, outcome "unknown", described as "fever"; ALOPECIA (non-serious), outcome "unknown", described as "lose her hair"; BLOOD IRON DECREASED (non-serious), outcome "unknown", described as "had low iron". Relevant laboratory tests and procedures are available in the appropriate section.  Additional information: It was reported that Consumer said 2 weeks after receiving the 1st dose of the Pfizer-BioNTech Covid-19 Vaccine, her 23-year-old daughter fell asleep for a day and a half. On a Monday afternoon, she noticed that her daughter didnt look so good. Her daughter said she was tired. In addition to that, she missed her period cycle for over about a week now. She said this was very unusual because her daughter is either early or never late. Consumer wants to know if the vaccine may have affected her daughters fertility. She also mentioned that her daughter was scheduled to receive the 2nd dose today but won't be getting it until she has her period back. Consumer also mentioned that her daughter had drug-induced lupus from Minocycline. She said her fingers and elbows were blowing up, and was a mess. She said she cannot even walk. She also said her daughter had several reactions to several medications. Consumer also mentioned that her daughter is allergic to leather and asked does vaccine cause infertility. Dont think she could do because she almost died when she took the, she took Minocycline and another medication (unspecified medication). she will not be able to have children because she is not menstruating. She was allergic when she took the medication(unspecified medication) in the past. She did have a little sore arm right after the vaccine, but it was no big deal.  But caller knew something was wrong 2 weeks after the vaccine when her Daughter was on the couch and she was so pale. She was so sleepy for 2 days. The caller is reluctant for her Daughter to receive the second dose of the vaccine that was scheduled for today, due to all her Daughter has experienced. Caller added her Daughter was on Minocycline for a whole year. She only had a couple of pimples. Her doctor advised her to go on this. It is the best thing. Her face blew up with nodules. She experienced drug induced Lupus. She ended up in the hospital and was put on Etodolac instead of Steroids and 3 weeks later, her Daughter called the local doctor because she was itching. She was full of spots when she lifted her shirt and the caller applied Calamine to help the itching. Then they treated her Daughter with steroids. Caller adds, she has a delayed reaction to everything, just like this with her period. I reported this 5 years ago, all her Daughter went through. Caller had no details about the Minocycline to provide. Caller states her daughter almost died from a cream (Aminocycline) and did have a reaction for a year and she called Pfizer about this and about her daughter's medications before getting them and had delayed reactions from those medications. The daughter has a history of lupus (about 2-3 years ago) and the lupus was treated with glucocorticoids and she no longer has problems with lupus. When her daughter was a senior in high school, she started on minocycline for acne (she could not give a specific date or dose). She stated she was not allergic to it right away and took it for about a year before she had any symptoms. She started with nodules on her elbows and then started having pain in her arms that eventually spread to her whole body. She stated she looked like a little old lady trying to walk and that was awful for her because she was an avid tennis player. She was no longer able to play tennis and lost all her friends causing her to be depressed. She took her to several different doctors and they took 19 vials of blood. They diagnosed her with drug induced lupus from the minocycline. As treatment, they put her on Etodolac. She thinks that was sometime around 2015-2017. She stated she seemed to be doing better but just felt sick and felt like she was still on minocycline. She then developed an itchy rash and blisters all over her chest and back. She used Calamine lotion to stop the itching. She stopped Etodolac and was put on steroids for 2 years. She is still depressed and is losing her hair due to the depression. She is taking Biotin for hair loss. The mother stated her daughter is healthy otherwise and takes no regular medications. Caller would like to know if a high ANA test result is a side effect of the covid vaccine. Her daughter started to lose her hair and their doctor called them yesterday ANA (lab test) was very high: 1200, had low iron and that she is going to have to take pills for the rest of her life. Caller would like to know if hair loss is a side effect of the covid vaccine. The caller has called Pfizer several times because the caller was afraid to give the Adult Pfizer Covid Vaccine to daughter because the caller's daughter has Drug Inducted Lupus Minocycline and was afraid to bother with anything. The caller's daughter finally received the Adult Pfizer Covid Vaccine. The caller called Pfizer because after two weeks the caller's daughter slept for two days, the caller was told this was because of the Adult Pfizer Covid Vaccine and was one side effect. The caller's daughter then missed menstrual cycle for two months. The bizarre thing is the patient received the First dose Adult Pfizer Covid Vaccine on 03Sep2021 and the second dose on 03Dec2021. The patient waited to receive the second dose adult Pfizer Covid Vaccine because patient had the side effects after first dose and wanted to make sure everything was back on and the patient's menstrual cycle was back and everything was okay. Second dose: Hair was shedding probably from stress: The patient received the second dose Adult Pfizer Covid Vaccine and did not think much of it. The patient went to the dermatologist because the patient's hair was shedding and probably from stress. Second dose: ANA for Lupus was quite high: The dermatologist took blood tests and freaked out stating the patient's ANA for lupus is quite high. The caller is flipping out as a mother and asked daughter how caller's daughter felt. The dermatologist stated the patient has to go to a rheumatologist and the dermatologist did not know why the ANA was high. The patient's Iron was a little bit low and the patient was on mensural cycle when patient went to the dermatologist, not too worried about that.  No follow-up attempts are possible. No further information is expected.