a tumor on the submandibular gland; joint pain; some cracking and popping; sore after the booster; muscle loss; His symptoms right now is progressively getting worse and his symptoms spiked after the Pfizer COVID-19 booster dose; high ferritin and iron levels; high ferritin and iron levels; tingle sensation in fingers and feet; finger coordination affected; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP) from medical information team. The reporter is the patient.  A 25 year-old male patient received bnt162b2 (BNT162B2) (Batch/Lot number: unknown) at the age of 25 years as dose 3 (booster), single for covid-19 immunisation. The patient had no relevant medical history. The patient's concomitant medications were not reported. Vaccination history included: Moderna covid vaccine (Moderna Covid Vaccine#1 , Date: 27Mar2021 , Lot: 021B21A, Expiry: Unknown, The tingling is all around his body. The tingling started with the first dose but then dramatically spiked after the second dose.), administration date: 27Mar2021, when the patient was 24 years old, for Covid-19 immunization, reaction(s): "tingling is all around his body", "Joint pain", "Chills, Shivering", "dizziness"; Moderna covid vaccine (Moderna Covid Vaccine #2: , Date: 24Apr2021, Lot: 040B21A, Expiry: Unknown, The tingling is all around his body. The tingling started with the first dose but then dramatically spiked after the second dose.), administration date: 24Apr2021, when the patient was 24 years old, for Covid-19 immunization, reaction(s): "tingling is all around his body", "Joint pain", "Chills,shivering", "dizziness". The following information was reported: BENIGN SALIVARY GLAND NEOPLASM (medically significant), outcome "unknown", described as "a tumor on the submandibular gland"; ARTHRALGIA (non-serious), outcome "unknown", described as "joint pain"; JOINT NOISE (non-serious), outcome "unknown", described as "some cracking and popping"; PAIN (non-serious), outcome "unknown", described as "sore after the booster"; MUSCLE ATROPHY (non-serious), outcome "not recovered", described as "muscle loss"; CONDITION AGGRAVATED (non-serious), outcome "not recovered", described as "His symptoms right now is progressively getting worse and his symptoms spiked after the Pfizer COVID-19 booster dose"; SERUM FERRITIN INCREASED (non-serious), BLOOD IRON INCREASED (non-serious), outcome "unknown" and all described as "high ferritin and iron levels"; PARAESTHESIA (non-serious), outcome "unknown", described as "tingle sensation in fingers and feet"; COORDINATION ABNORMAL (non-serious), outcome "unknown", described as "finger coordination affected". The patient underwent the following laboratory tests and procedures: electromyogram: (21Dec2021) unknown result; haemochromatosis: (Jan2022) negative; magnetic resonance imaging neck: (Nov2021) tumor submandibular gland that was benign, notes: tumor submandibular gland that was benign; serum ferritin: (Jan2022) 831 ng/ml; transferrin saturation: (Jan2022) 50 %. Clinical course: Patient has been experiencing his ongoing symptoms of joint pain, some cracking and popping, tingliness in the body, including muscle loss for the past year. he has talked to his physician as well as a neurologist but they do not see anything wrong. he was on a dead end and his symptoms has been going on for a while now. The patient States 3 weeks ago he noticed his left arm, his left rotator cuff started popping and cracking. The popping and cracking arrived in his left shoulder joint 3 days after getting the shot. He didn't have that before. The patient got the Moderna COVID-19 vaccine as his primary series last year Mar and Apr and he developed tingling sensation and joint pain which usually goes away and is not as severe. he has had ongoing joint pain since last Apr, and a tingling sensation throughout his body but especially in his fingers and feet. The tingling started with the first dose but then dramatically spiked after the second dose. With the first 2 shots, there were different areas on his body that were popping and cracking, for example like his right forefoot, where the arch is. Right forefoot was popping and cracking: Started after the first 2 doses, maybe 3 months after Apr2021. His symptoms right now was progressively getting worse and his symptoms spiked after the Pfizer COVID-19 booster dose. he has high ferritin and iron levels and he isn't sure if it is because of the vaccine. He has been trying to see an neurologist and had iron studies conducted. His iron levels were high. States he had an EMG conducted too and his doctor sent him to a hematologist. His iron saturation level was at 50% which is on the high end and his ferritin levels were 831 and they should be 400. He then got tested for hemochromatosis to see if that was the cause for the joint pain and that was negative. he has been having muscle loss and muscle atrophy and that was the reason why he had the EMG and the reason for his tingling. The tingling is all around his body. It all started with the first does and then got worse with the second dose. The muscle loss and atrophy began in the beginning but it was so miniscule, overtime it accumulated over the year, he's noticed then over the course of the next months his finger coordination was affected. States he was dropping things more frequently and the muscles in his hands are deteriorating, he noticed its been ongoing and in the beginning on his palms he could see the blue area with veins in the fatty area connected to the thumb, but in the beginning he didn't have that and it was muscle definition so he didn't notice it and now it is wrinkly and he sees more veins in the palms of his hands. his body progressively started cracking and popping. With his fingers it feels like its creaking, like a creaking sensation when he flexes more and move them, that has gradually gotten worse. He can reproduce the creaking on demand, that's how worse its gotten. The patient had done cervical MRI as he was having all the tingling and nerve issues and found a tumor on the submandibular gland that got removed on 29Dec2021 and it was benign. The patient states that the morning when he woke up, with both doses, he woke up with chills, joint pain, shivering and a little bit of dizziness. It felt like he had gotten into a car accident after waking up. He was sore after the booster. The patient had booster sometime in the morning. The patient had not received any additional vaccines administered on same date. The AE(s) donot require a visit to Emergency Room/Physician Office. The patient had no vaccination within 4weeks prior vaccinations. The patient had no AE(s) following prior vaccinations.   The lot number for bnt162b2 was not provided and will be requested during follow up.