Dull headache; Exhaustion; very bad nausea; vomiting 6x over the course of next 12 hours; Chills; 2 hives on legs; hot sweating flashes; Temperature rose one degree; Lost 5 hours sleep; Could not eat or drink; headache; Stuffy nose; shallow breathing; This is a spontaneous report from a contactable consumer, the patient. A 36-year-old non-pregnant female patient received the first dose of BNT162b2 (PFIZER-BIONTECH COVID-19 mRNA VACCINE; Lot Number: ER 8732) via an unspecified route of administration in the right arm on 25Mar2021 at 10:45 (at the age of 36-years-old) as a single dose for COVID-19 immunisation. Medical history included radiofrequency ablation performed on lumbar on 4 levels on 18Feb2021 for spine injury sustained post motor vehicle accident (MVA) on 20Dec2019. Concomitant medications included cortisone (MANUFACTURER UNKNOWN) and pregabalin (PREGABA) for unknown indications from unknown dates. The patient previously received pregabalin (MANUFACTURER UNKNOWN), meloxicam (MANUFACTURER UNKNOWN), paracetamol (TYLENOL), multivitamin (MANUFACTURER UNKNOWN), lysine (MANUFACTURER UNKNOWN), collagen (MANUFACTURER UNKNOWN), turmeric, fish oil (MANUFACTURER UNKNOWN), glucosamine (MANUFACTURER UNKNOWN) and norethisterone (HEATHER) for birth control. The patient previously received amoxicillin (MANUFACTURER UNKNOWN) and experienced drug allergy. Prior to the vaccination, the patient was not diagnosed with COVID-19. Since the vaccination, the patient had not been tested for COVID-19. The patient did not receive any other vaccines within four weeks prior to the vaccination. On 29Mar2021 at 05:30, the patient experienced stuffy nose, headache and shallow breathing. On 30Mar2021, all the symptoms were more pronounced. On 31Mar2021, the patient had most severe day. The patient experienced painful headache very severely limiting function, shallower breathing and very bad nausea began at 12:00 followed by vomiting 6 times over the course of next 12 hours. The patient could not eat or drink. Temperature rose one degree in the evening and the patient had chills and hot sweating flashes with mostly chills. Nausea continued into the night and the patient lost 5 hours of sleep. The patient had 2 hives on the legs. The patient almost went to emergency room (ER). The patient could drink around 00:00. The headache was subsided around 02:00. The patient could eat around 03:00. On 01Apr2021, nausea reduced greatly but still was uncomfortable. Breathing was improved with no more chills or hot flashes. The patient also experienced dull headache and exhaustion. The adverse events did not result in a visit to the doctor or other healthcare professional office/clinic visit, and emergency room/department or urgent care. The patient iced her head with compress for headache and the patient did not receive any treatment for the events stuffy nose, shallow breathing, very bad nausea, vomiting 6x over the course of next 12 hours, could not eat or drink, temperature rose one degree, chills, hot sweating flashes, lost 5 hours of sleep, 2 hives on the legs, dull headache and exhaustion. The clinical outcomes of the events chills and hot sweating flashes were resolved on 01Apr2021 while that of the headache, stuffy nose, shallow breathing, very bad nausea, vomiting 6x over the course of next 12 hours, could not eat or drink, temperature rose one degree, lost 5 hours of sleep, 2 hives on the legs, dull headache and exhaustion were resolving at the time of the report.   No follow-up attempts are needed. No further information is expected.