Numbness below the knee; Severe joint pain; Muscle pain; Tiredness; Sore arm and swelling of the injection site; Sore arm and swelling of the injection site; Body aches; This is spontaneous report received from a contactable consumer (Patient).   A 67-year-old female patient received first dose of BNT162B2 (PFIZER-BIONTECH COVID-19 MRNA VACCINE, Lot number: EP7533 and expiry date: 31Jul2021) via an unspecified route of administration into left arm on 16Apr2021 as dose 1, single for Covid-19 immunization. Medical history included: Hypothyroidism about 8 years ago. The patient said, she has allergies to a number of antibiotics. The patient had an allergic reaction to antibiotics and cortisone shot. She was very apprehensive. The patient said the doctor advised her to get the shot, the doctors said they thought it would be good to get the shot. The patient had the cortisone shot twice in her life and she never had a problem. She says she had one in her knee, did have a flare up but it could have been that he hit a nerve. The patient took cortisone number of years ago. The patient neither took any prior Vaccinations within 4 weeks nor received any other vaccines on same date of Pfizer vaccine. Concomitant medications included: Ascorbic Acid (VITAMIN C) since years, Vitamin B Complex (Patient has been taking this for years and years, a long time, 40, 50). The patient reported that 3 weeks ago, she had her vaccine, the first one, on 16Apr2021 and was nervous about getting the vaccine. After the shot that evening (on 16Apr2021), her arm was sore and there was swelling of the injection site and had Tiredness. The patient was told that the arm would be sore where the injection site is. She was really tired, she took a shower, she iced it, and it went away Monday. The patient had was a flare up which was where, maybe 5 hours after the shot, you can't move; she couldn't move her leg. She spoke to the orthopedic doctor; he called her in the morning and told her he had it in his hand once. She says he said when he was given it it went away, it will go away, and it did go away. Then had body aches (In Apr2021). On 20Apr2021, the patient had muscle pain and said now it was more joint pain and the joint pain has not gone away. She was not certain if it is muscle pain or joint pain. It was in the wrist and hand, and it was in the scapula area and the neck, and she also has numbness below the knee; that was what she was experiencing right now. On 21Apr2021, joint pain was bad enough. Therefore, she had to take two Naproxen Sodium (ALEVE 220 mg caplet) at 220 mg twice a day (one in the morning and one in the evening with food) for joint pain on 21Apr2021. The patient took in the late morning and evening, sometimes after dinner, twice a day. She doesn't like to take it, she reduced it to one. The patient was not taking the second vaccine as it has caused her lot of discomfort. She saw an allergist who thought it would dissipate. The allergist said if she took the second shot then it will be a lot worse. The patient has been taking aleve at two a day for a week, 10 days, at two a day. The patient had bloodwork done that showed no antibodies for COVID-19. Outcome of Sore arm and swelling of the injection site was resolved with Sequel on 19Apr2021. Tiredness was recovered on 16Apr2021. Outcome of other events was unknown.   No follow-up attempts are needed. No further information is expected.