The first shot to the second shot, was so bad; This is a spontaneous report from a contactable consumer. This 66-year-old male consumer (patient) reported that:  Patient characteristics:  Age at time of onset of reaction/event: 65 Age at time of onset of reaction/event (Unit): year Height (cm): 183 Sex: Male  Relevant medical history and concurrent conditions: Structured information(Patient episode name): Crohn's disease Patient Medical comments: Verbatim: Crohn's disease  Relevant medical history and concurrent conditions: Structured information(Patient episode name): Asthma   Patient Medical comments: Verbatim: Asthma    Reaction(s)/Event(s): Reaction/event as reported by primary source: Injection site pain   Reaction/event in MedDRA terminology (LLT): Injection site pain   Reaction/event MedDRA term (PT) : Injection site pain    Reaction(s)/Event(s): Reaction/event as reported by primary source: I was very tired, I had headaches, muscle pain    Reaction(s)/Event(s): Reaction/event as reported by primary source: I had a low grade fever, slight swelling in the arm, site is red, didn't feel well, whole arm was pain    Reaction(s)/Event(s): Reaction/event as reported by primary source: My body did not have the chance to build up antibodies and response.  Drug(s) Information: Characterization of drug role:Suspect Proprietary medicinal product name: Covid Vaccine Batch/lot number: EW0168    Date of start of drug: 16Aug2021 Action(s) taken with drug: Unknown  Drug(s) Information: Characterization of drug role: Suspect Proprietary medicinal product name: Unspecified Medication Batch/lot number: Unknown Action(s) taken with drug: Unknown  Narrative case summary and further information: Case narrative:  Selected Report Type: Initial Patient Ethnicity: (Ethnicity withheld) Is the patient also the reporter? Yes Reporter type: Consumer or other non health professional Specify Consumer or other non health professional: Self Reporter telephone: (Phone withheld)  Primary / Prescribing Healthcare Professional Info HCP postal address:  Dates for Injection site pain: (From: Unspecified To: Unspecified) Dates for I was very tired, I had headaches, muscle pain: (From: Unspecified To: Unspecified) Dates for I had a low grade fever, slight swelling in the arm, site is red, didn't feel well, whole arm was pain: (From: Unspecified To: Unspecified) Dates for My body did not have the chance to build up antibodies and response.: (From: Unspecified To: Unspecified)  Is Covid Vaccine a Pfizer product? Yes Covid Vaccine manufacturer: Unspecified Dates for Covid Vaccine: (Start: 16Aug2021 Stop: Unspecified) NDC number of Covid Vaccine: Unknown UPC number of Covid Vaccine: Unknown Expiry Date of Covid Vaccine: Unknown  Is Unspecified Medication a Pfizer product? Unspecified Unspecified Medication manufacturer: Unspecified Dates for Unspecified Medication: (Start: Unspecified Stop: Unspecified) NDC number of Unspecified Medication: Unknown UPC number of Unspecified Medication: Unknown Reason for no lot number: of Unspecified Medication: Complaint identified after call completed Expiry Date of Unspecified Medication: Unknown  Other Products: Yes  Patient History: Yes Patient history: Crohn's disease (From: Unspecified To: Unspecified) Patient history: Asthma (From: Unspecified To: Unspecified)  Additional Context: Concern: Consumer stated, "I had kind of few side effects for third shot. I had the first shot. I had no side effects. Not even the soreness of the injection site. I had the second shot. I did not have nothing at all. Even no tiredness, Not even a warmth in the arm. Nothing. On my third shot, Because I am immuno-compromise that I take a immuno-compromise drug, a chemo drug (further clarification unknown if consumer was suffering from side effects hence captured as suspect of unspecified medication). I had in site, You know, Injection site pain. I was, You know, It hurt for over a week, Almost a week and half. Just was started feeling better. I was very tired, Tiredness. I had headaches, muscle pain kind of all over. I had a low grade fever, Slight swelling in the arm, Site is red, Didn't feel well, whole arm was pain so, I am not sure. What's going on? My guess would be that, The first shot to the second shot, Was so bad. My body did not have the chance to build up antibodies and response. So, When the third shot came around, It was really worked."  Suspect confirmed: Pfizer Covid19 Vaccine.  Consumer was told about the role of Pfizer Drug Safety and the Pfizer Medical information.  Consumer stated: "No. Not at all. I am feeling fine now. It's just, I am trying to report what I had."  Date for first shot: Consumer stated, "05Feb2021 (not clarified)." LOT#: Consumer stated, "EN5318."  Date of Second shot: Consumer stated, "26Feb2021." LOT#: Consumer stated, "EN6201."  Date of third shot: Consumer stated, "16Aug2021."  LOT#: Consumer stated, "EW0168(captured as per the verbatim)."  Medical Conditions: Consumer stated, "I do have Crohn's disease and that's why, I take the medicine. A chemo drug to keep my Crohn's under control. I do also have asthma."  Regular Medication: Consumer stated, "It's 6MP. I take mother drugs. I take Pantoprazole. I take mild Calcium Fosamax. 6MP. It's Mercaptopurine and Purinethol (drug names not clarified, Hence not captured in tab)."  Lab Test: Consumer stated, "No. Blood work done. No."  When probed if taken any other vaccine: Consumer stated, "No. None."  When probed if any other family member is facing the same issue: Consumer stated, "No."  Date of Birth: Consumer stated, "(DOB withheld).  Weight: Consumer stated, "About 295 pounds. Actually, I am 290, I measured myself today 290 (Not confirm, Hence not captured in tab)."  Email: Consumer stated, "(email withheld) (not clarified further, Hence not captured in tab)."  Facility Name: Consumer stated, "(name and address withheld) (address not clarified)."  Treatment: Consumer stated, "No. I was just happy. I had response."  Follow-Up (08Sep2021): Follow-up attempts are completed. No further information is expected. This is a spontaneous report from a contactable consumer or other non hcp.   A 66-years-old male patient received bnt162b2 (BNT162B2), dose 1 via an unspecified route of administration on 05Feb2021 (Batch/Lot Number: EN5318) as DOSE 1, SINGLE, dose 2 via an unspecified route of administration on 26Feb2021 (Batch/Lot Number: EN6201) as DOSE 2, SINGLE for covid-19 immunisation  .  Medical history included crohn's disease from an unknown date and unknown if ongoing I do have Crohn's disease and that's why, I take the medicine. A chemo drug to keep my Crohn's under control , asthma from an unknown date and unknown if ongoing. Concomitant medication(s) included calcium (CALCIUM) taken for an unspecified indication, start and stop date were not reported; alendronate sodium (FOSAMAX) taken for an unspecified indication, start and stop date were not reported; pantoprazole (PANTOPRAZOLE) taken for an unspecified indication, start and stop date were not reported; mercaptopurine (PURINETHOL) taken for an unspecified indication, start and stop date were not reported; mercaptopurine (6-MP) taken for an unspecified indication, start and stop date were not reported.  The patient experienced the first shot to the second shot, was so bad (feeling abnormal) (non-serious) on an unspecified date with outcome of recovered.  The patient underwent lab tests and procedures which included weight: about 295 lbs on     , weight: 290 lbs on 29Aug2021 Actually, I am 290, I measured myself today 290 (Not confirm, Hence not captured in tab).  The action taken in response to the event(s) for bnt162b2 was not applicable.