headache; completely occluded vision; right eye went completely blurry; it feels as if something is irritating it; This is a spontaneous report received from a non-contactable reporter(s) (Consumer or other non HCP). The reporter is the patient.  A 68-year-old female patient (not pregnant) received BNT162b2 (BNT162B2), on 25Mar2022 at 11:00 as dose 3 (booster), single (Batch/Lot number: unknown) at the age of 68 years, in right arm for covid-19 immunisation. The patient's relevant medical history included: "Covid" (unspecified if ongoing), notes: if covid prior vaccination: Yes. Concomitant medication(s) included: LEVOTHYROXINE; ESTROGEN. Vaccination history included: BNT162b2 (Dose Number: 2, Batch/Lot No: Unknown. Unable to locate or read the details, Location of injection: Arm Left, Vaccine Administration Time: 10:00 AM), administration date: 04Aug2021, when the patient was 67-year-old, for COVID-19 immunization, reaction(s): "Dose Number: 2; 4Aug2021/Dose Number: 1; 1Jun2021"; BNT162b2 (Dose Number: 1, Batch/Lot No: Unknown. Unable to locate or read the details, Location of injection: Arm Left, Vaccine Administration Time: 02:00 PM), administration date: 01Jun2021, when the patient was 67-year-old, for COVID-19 immunization. The following information was reported: BLINDNESS (medically significant) with onset 25Mar2022 at 18:00, outcome "not recovered", described as "completely occluded vision"; EYE IRRITATION (non-serious) with onset 25Mar2022 at 18:00, outcome "not recovered", described as "it feels as if something is irritating it"; VISION BLURRED (non-serious) with onset 25Mar2022 at 18:00, outcome "recovering", described as "right eye went completely blurry"; HEADACHE (non-serious) with onset 26Mar2022, outcome "recovered" (27Mar2022). The events "completely occluded vision", "right eye went completely blurry", "it feels as if something is irritating it" and "headache" required physician office visit. Therapeutic measures were taken as a result of blindness, vision blurred, eye irritation, headache.  Clinical information: The patient diagnosed with COVID-19, Prior to vaccination. Since the vaccination, the patient has been tested for COVID-19. The patient received other medications within 2 weeks of vaccination Levothyroxine, estrogen. Location of injection for vaccine received same date: Pfizer  Arm. Facility where the most recent COVID-19 vaccine was administered at Pharmacy or Drug Store. The patient did not receive any other vaccines within 4 weeks prior to the COVID vaccine. It was reported that within 5 hours of the booster shot, right eye went completely blurry, with completely occluded vision. Could only see light but no color or shapes, as if standing in a cloud. There is a rough feeling on the surface of the eye, and it feels as if something is irritating it. The following day a headache began that lasted 24 hours. The blurred vision has persisted for the past 12 days since, with some improvement. There is still a rough feeling and vision has not returned to normal, although she can now see they will enough to work and drive. The adverse event result in doctor or other healthcare professional office/clinic visit. The patient received for the adverse events included Eye drops to help with irritation.  No follow-up attempts are possible; information about lot/batch number cannot be obtained. No further information is expected.