Quick onset headache that worsened into the night to become unbearable; major fatigue/fatigue so severe/Fatigued to the point I could not put forth any effort to speak or see well; Muscle aches; immediate pain at injection site; Nausea all night/nausea was so bad; Throwing Up/could barely hold down any water, usually would vomit up; not able to move around/could barely get up to go to the bathroom 10 feet away; Not able to eat (Lack of Appetite)/could not eat; restless sleep; Weakness so severe; nausea was so bad to the point of dry heaving; This spontaneous case was reported by a consumer and describes the occurrence of MOVEMENT DISORDER (not able to move around/could barely get up to go to the bathroom 10 feet away), DECREASED APPETITE (Not able to eat (Lack of Appetite)/could not eat), POOR QUALITY SLEEP (restless sleep), ASTHENIA (Weakness so severe) and RETCHING (nausea was so bad to the point of dry heaving) in a 66-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 013A21A and 004M20A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     The patient reported she had no medical conditions and was taking no concomitant medications.    On 30-Jan-2021 at 4:45 PM, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 27-Feb-2021 at 4:45 PM, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. On 27-Feb-2021, the patient experienced MOVEMENT DISORDER (not able to move around/could barely get up to go to the bathroom 10 feet away), DECREASED APPETITE (Not able to eat (Lack of Appetite)/could not eat), POOR QUALITY SLEEP (restless sleep), ASTHENIA (Weakness so severe), RETCHING (nausea was so bad to the point of dry heaving), VOMITING (Throwing Up/could barely hold down any water, usually would vomit up) and NAUSEA (Nausea all night/nausea was so bad). On 27-Feb-2021 at 4:45 PM, the patient experienced VACCINATION SITE PAIN (immediate pain at injection site). On 27-Feb-2021 at 5:00 PM, the patient experienced HEADACHE (Quick onset headache that worsened into the night to become unbearable), FATIGUE (major fatigue/fatigue so severe/Fatigued to the point I could not put forth any effort to speak or see well) and MYALGIA (Muscle aches). On 03-Mar-2021, MOVEMENT DISORDER (not able to move around/could barely get up to go to the bathroom 10 feet away) had resolved. On 05-Mar-2021, DECREASED APPETITE (Not able to eat (Lack of Appetite)/could not eat), POOR QUALITY SLEEP (restless sleep), ASTHENIA (Weakness so severe), RETCHING (nausea was so bad to the point of dry heaving), VACCINATION SITE PAIN (immediate pain at injection site), HEADACHE (Quick onset headache that worsened into the night to become unbearable), VOMITING (Throwing Up/could barely hold down any water, usually would vomit up), FATIGUE (major fatigue/fatigue so severe/Fatigued to the point I could not put forth any effort to speak or see well), MYALGIA (Muscle aches) and NAUSEA (Nausea all night/nausea was so bad) had resolved.            The patient reported she was "bed ridden and helpless for 4 days".  She then started to get a little better on the 5th day and 6th day, returning to normal on the 7th day. She stated, "I have never ever been this sick before."  The headache was treated with an unspecified pain relief medication.  The patient did not seek medical attention for the events  No concomitant medication details were provided. No treatment medication details were provided.   Most recent FOLLOW-UP information incorporated above includes: On 30-Apr-2021: The patient completed the vaccine adverse event reporting form.  Demographics and events added.  Narrative updated.