Second dose: Fatigue; Second dose: Arm was a little stiff and sore; Second dose: Arm was a little stiff and sore; This is a spontaneous report received from a contactable reporter(s) (Consumer or other non HCP) for a Pfizer sponsored program. The reporter is the patient.  A 57 year-old male patient received bnt162b2 (BNT162B2), administration date 29Apr2021 (Batch/Lot number: unknown) as dose 2, single for covid-19 immunisation. Relevant medical history included: "Spinal cord injury", start date: 1988 (unspecified if ongoing); "Psoriatic arthropathy" (ongoing), notes: he was diagnosed with psoriatic arthritis when he was 27 years old.; "Lyme disease" (unspecified if ongoing), notes: he was diagnosed with Lyme disease 5 years ago; "Spinal stenosis" (ongoing), notes: the spinal stenosis developed and he had surgery twice on the C4, C5, and C6 vertebrae in his neck when he was 48 or 49 years old; "HLA-B*27 positive" (ongoing); "Attention deficit hyperactivity disorder" (ongoing), notes: he was diagnosed with ADD when he was 40.; "Low Vitamln D" (ongoing), notes: he has low Vitamin D that doesn't respond to exogenous sources of Vitamin D or what he eats; "incomplete paralysis" (ongoing), notes: his second spine surgery when he was 48 or 49 years old left him with lesions on his spinal cord and permanent spinal cord damage; "Fibromyalgia" (ongoing); "Tendon disorder" (ongoing); "Depression" (ongoing); "Arthritis" (unspecified if ongoing); "Pollen allergy" (unspecified if ongoing); "Muscle relaxant therapy" (unspecified if ongoing). Concomitant medication(s) included: ENBREL taken for arthritis, stop date: Apr2021; METHOTREXATE taken for arthritis, stop date: Apr2021; ADDERALL taken for attention deficit hyperactivity disorder; FLONASE ALLERGY RELIEF taken for seasonal allergy; SERTRALINE taken for depression, start date: 2021; BACLOFEN taken for muscle relaxant therapy; BUPRENORPHINE AND NALOXONE. Vaccination history included: Covid-19 vaccine moderna (DOSE 1), administration date: 01Apr2021, for Covid-19 immunization.  The following information was reported: FATIGUE (non-serious) with onset 01May2021, outcome "recovered" (06May2021), described as "Second dose: Fatigue"; MUSCULOSKELETAL STIFFNESS (non-serious) with onset Apr2021, outcome "recovered" (May2021), PAIN IN EXTREMITY (non-serious) with onset Apr2021, outcome "recovered" (Apr2021) and all described as "Second dose: Arm was a little stiff and sore".  Additional information: Reporter was given consent to contact. Patient started using Enbrel when he was 37 years old. He began using Methotrexate when he was 42 years old. He began using Adderall when he was 40. He has been using Flonase for 3 years off and on. He just started taking the Sertraline this year before he received the Covid-19 vaccine. He started taking Baclofen when he was 47. He has been taking Suboxone for 2-2.5 years. He was diagnosed with Lyme disease 5 years ago. Caller reported that the last time that he had a tick was when he was 28 years old. Caller reported that he had multiple Lyme disease tests because of joint pain. Caller reported that it wasn't until he was asked where he lived and the last time that he noticed a tick on him that an area specific Lyme disease test was run that came back positive. Caller reported that he had undiagnosed Lyme disease for 25 years. Caller reported the spinal stenosis developed from his spinal cord injury in 1988. Caller reported that the spinal stenosis developed and he had surgery twice on the C4, C5, and C6 vertebrae in his neck when he was 48 or 49 years old. Caller reported that the first surgeon didn't do a very good job and that he had to have a corpectomy during the second surgery. He has low Vitamin D that doesn't respond to exogenous sources of Vitamin D or what he eats. Caller reported that he has records going back forever of his low Vitamin D levels. Caller reported that even living on a lake and spending hours in the sun, he still had low Vitamin D. Caller reported that the low Vitamin D is hereditary and his children have it as well. Caller reported that his second spine surgery when he was 48 or 49 years old left him with lesions on his spinal cord and permanent spinal cord damage. Caller reported that he has incomplete paralysis and that he is a paraplegic but can walk and talk and poop and drink and eat. Caller reported that he will spend his final years as a full paraplegic. Caller reported that he received both doses of the Pfizer Covid-19 vaccine. Caller reported that he experienced fatigue with both doses of the Covid-19 vaccine. Caller reported that he has arthritis, and that after receiving the Covid-19 vaccine, all of his joint pain went away. Caller reported that rheumatology could get Pfizer one of 8 or 9 different physicians since his health care is through the RA as a disabled patient. Caller reported that the fatigue began on the evening of the third day after receiving the first dose of the Covid-19 vaccine on 01Apr2021. Caller reported that the fatigue was like a light switch. Caller reported that he was ok then was hit suddenly with fatigue. Caller reported that the fatigue kept him in bed for a good day and a half and that he felt drained for another 3 to 5 days afterward. Caller reported that the fatigue after his second dose of the Covid-19 vaccine began maybe the 2nd day after he received his second dose of the Covid-19 vaccine on 29Apr2021. Caller reported that he was tired but not anything like the first time. Caller reported that after the first dose of the Covid-19 vaccine, his fatigue was a 10, off the charts, worst ever. Caller reported that the fatigue following the second dose of the Covid-19 vaccine was manageable for a day or 2 and lasted for maybe 4-5 days total. Caller reported that he would have called in from work due to the fatigue following the first dose of the Covid-19 vaccine. Caller reported that if he'd had a personal day to burn, he would have taken a day off due to the fatigue from the second dose of the Covid-19 vaccine, but otherwise it was not a big deal. Second dose: Arthritis joint pain went away: Caller reported that it is going on maybe 2.5 to 3 weeks and he has no joint pain. Caller reported that he has had arthritis, fibromyalgia, muscle pain, tendon thickening that goes along with that, and psoriasis type plaques for years. Caller reported that he has no RNA markers, but that he has those types of immunological conditions. Caller stated that he felt that it was important for him to report his experience with the Covid-19 vaccine with Pfizer. Caller reported that he is positive for the HLA-B27 gene. Caller reported that it is thought that there could be some sort of correlation between the HLA-B27 gene and an interruption in the inflammatory feedback loop. Caller reported that he is willing to do whatever for Pfizer to give Pfizer all the mental and physical samples that they want. Caller stated that he thinks that Pfizer is on to something. Caller reported that he doesn't care if he's only one in a million, that it's astounding to him that his arthritis joint pain has gone away. Caller reported that he probably won't be going back on the Methotrexate or the Enbrel until the relief from his arthritis joint pain goes away, which it may not. First dose: Slight chills: Caller reported that the chills were insignificant. Caller reported that he experienced the chills in the evening when he was going to bed on 01Apr2021. Caller reported that he didn't wake up on 02Apr2021 with the chills and didn't wake up sweating in the middle of the night. Caller reported that his wife said that he felt a little warm but the caller didn't take his temperature. Caller reported that he didn't care that much about the chills. Caller reported that the chills were maybe a 1 on a scale of 1 to 10. First dose: Severe muscle pain in neck and shoulders: Caller reported that the severe muscle pain in his neck and shoulders began on the evening of the third day following the first dose of the Covid-19 vaccine. Caller reported that the severe muscle pain was like a light switch, coming on suddenly. Caller reported that he is a spinal cord injury patient and normally experiences pain. Caller reported that the muscle pain in his neck and shoulders wasn't his normal pain and wasn't never pain. Caller reported that the pain really kicked his butt. Caller reported that he hasn't had that type of pain in a while. Caller reported that the pain was worse than delayed onset muscle soreness from a strenuous work out. First dose: Arthritis pain may have gotten slightly worse: Caller reported that after the first dose of the Covid-19 vaccine, his arthritis pain may have gotten worse for maybe a week or two. Caller reported that about a week before he received the second dose of the Covid-19 vaccine, he did feel better. Caller reported that the arthritis pain may have felt like it got slightly worse because he felt so badly. Caller reported that the side effects after the first dose weren't a "God, I think I'm getting sick" and takes 2-3 days to feel bad. Caller reported that it was like he was ok 3 hours ago and then it was bad. Second dose: Arthritis joint pain went away: Caller reported that maybe in the last 7 to 10 days, he woke up and he knows that he didn't notice it at first, but then said to his wife that he didn't have any joint pain. Caller reported that he thought to himself, don't get used to that, you know how this works when the arthritis joint pain first went away. Caller reported that now it's been a week, and he decided it was time to let people know. Caller reported that he hasn't gotten this type of relief from his arthritis joint pain since his first month of being on Enbrel when he was 37 years old. Caller reported that after he first started using Enbrel, he felt 18 years old again. Caller reported that he almost feels the same way now after the Covid-19 vaccine if he didn't have hardware in his neck from spinal surgery. Caller reported that his arm was a little stiff and sore following both doses of the Covid-19 vaccine. Caller reported that his arm was stiff and sore for 4 days maybe following each dose of the Covid-19 vaccine. Caller reported that after a while, he tens to ignore things after dealing with joint pain for so many years. Caller reported that his arm was a little more stiff following the first dose of the Covid-19 vaccine. Sertraline: Caller reported that he has been on many different antidepressants over the years and has never gotten relief. Caller did not provide details for prior medications. Caller reported that the hospital staff instructed the caller to stop taking the Methotrexate and Enbrel a week before getting the Covid-19 vaccine and not to take them for a week after. Caller reported that he deviated from the instructions due to everything being new and out there. Caller reported that he got a feeling from the person telling him what to do and asking him questions that the person was shooting from the hip. Caller reported that he didn't take the Methotrexate and Enbrel for a month prior to the first dose of the Covid-19 vaccine. Caller reported that he took the Methotrexate and Enbrel once in between the 2 doses of the Covid-19 vaccine and hasn't taken it since for a month. Caller reported that if the relief from his arthritis joint pain following the Covid-19 vaccine continues, he is not planning to start the Methotrexate and Enbrel again. Suboxone: Caller reported that while the Suboxone did nothing for joint pain and helped maybe for some muscle pains, it gets rid of the opioids that he had been on for many years after the spinal cord injury and surgeries. Caller reported that he is going to call the hospital because the hospital pulls all kinds of stuff. Caller reported that he is offering any blood or tissue or imaging or labs that Pfizer needs. Caller reported that Pfizer can mail him paperwork and he would be more than happy to sign as well as be considered for any other similar trials. Caller reported that he was told that he got the Pfizer Covid-19 vaccine, but when he found his vaccine card, the Moderna Covid-19 vaccine was listed as being administered. Caller reported that he wouldn't have gotten the Covid-19 vaccine if he had known that it was the Moderna vaccine. Caller reported that he is still happy to have Pfizer follow up with him with further questions or for further research. Communication was reported as Caller reported that he received the Pfizer Covid-19 vaccine, but when he found his vaccine card at the end of the report, saw that he had received the Moderna Covid-19 vaccine. Caller provided with reportum reference number, A06LWIND, and notified of survey prior to disconnect.  No follow-up attempts are possible; information about lot/batch number cannot be obtained. No further information is expected.