High fever; Chills; Body aches; Headache; Heart rate elevated/heart rate went up/heart rate was high; Blood pressure elevated/blood pressure went up to 197/89/ blood pressure was back up to 151 and 187; Tired and exhausted; Weakness/extremely weak; Rapid heart palpitations; Got cold and really hot and that would go back and forth; This is a spontaneous report from a contactable consumer (patient). A 53-year-old female patient received bnt162b2 (PFIZER-BIONTECH COVID-19 VACCINE, Solution for injection, Batch/Lot Number: ER8727), dose 2 intramuscular, administered in Arm Right in the muscle on 14Apr2021 17:30 as 2nd dose, single for covid-19 immunisation administered in Clinic. Medical history included hypotension (She is somebody whose blood pressure is always low. Her problem is it drops too low at night-time. She does not take medication to bring it up). Concomitant medication(s) included pravastatin at 20 mg once daily for blood cholesterol increased; hydrochlorothiazide at 12.5 mg for hypertension; ibuprofen (ADVIL [IBUPROFEN]) at 2 Advil, 4x/day (four times a day) for pyrexia, pain in extremity. Patient previously took first dose of BNT162B2 (Batch/Lot Number: EN6206), dose 1, administered in Arm left in the muscle on 24Mar2021 for covid-19 immunisation. The patient reported, she took the second shot for Pfizer and the day she took it her blood pressure and heart rate went up on 14Apr2021 22:30. She was tired and exhausted on 14Apr2021 21:00. She went to ER and they did X-ray, EKG, Blood work and everything was normal. Her blood pressure went up to 197/89. She has been in bed since Wednesday. She had normal high fever, chills, body aches, and was extremely weak on 15Apr2021 06:00. She is taking 2 Advil every 4 hours. If she does not, the fever and body aches come back. Yesterday, she did not immediately take the Advil every 4 hours and she felt, body aches and chills. Now she has an alarm on her cell phone, so she does not miss it. When fever started, the chills started. She got cold and really hot and that would go back and forth. When she went to ER with high blood pressure, that is when she had a headache on 14Apr2021 22:30. She left house about 11:30 pm when her blood pressure had gone up to 197. They did an EKG, Blood work and, X-Ray and they checked her thyroid, and everything was normal. They had no idea why her heart rate was high, or her blood pressure was high. The paperwork from the ER said she came for rapid heart palpitations. She went in for high blood pressure. She did have a high heart rate as well. They gave her an IV medication and her blood pressure went to 137. They let her go and 10 hours later, her blood pressure was back up to 151 and 187. She is the one who prescribed medication to lower her blood pressure. She prescribed Hydrochlorothiazide 12.5 mg. The doctor said to use it only if her blood pressure goes up to 150. They have her entire chart, and her concern is that her blood pressure drops. They did not want her to have it drop. The doctor said to make sure only take it if over 150. Today it was 181, but she is concerned to take this medication and she has not taken it. She is alone in her house. Prior Vaccinations within 4 weeks were none. The outcome of events were not recovered.  No follow-up attempts are needed. No further information is expected.