Then, on Sep2021 he received the booster and 24 hours later he lost power on arms and legs and ended up in hospital/ wound up losing power in his arms and legs and wound up on the floor; This is a spontaneous report received from a non-contactable reporter(s) (Consumer or other non HCP) from medical information team. The reporter is the patient.  A male patient received BNT162b2 (BNT162B2), in Sep2021 as dose 3 (booster), single (Batch/Lot number: unknown) for covid-19 immunisation. The patient's relevant medical history and concomitant medications were not reported. Vaccination history included: Bnt162b2 (Got the Pfizer CN6206, dose 1, single, Got 2 vaccines and had no reaction, to the regular ones), administration date: Mar2021, for Covid-19 immunization, reaction(s): "No reactions"; Bnt162b2 (A couple of weeks later, got the second vaccine and had no problems what so ever, no reactions, dose 2, single), administration date: Mar2021, for Covid-19 immunization, reaction(s): "No reactions". The following information was reported: MONOPLEGIA (hospitalization, medically significant) with onset Sep2021, outcome "unknown", described as "Then, on Sep2021 he received the booster and 24 hours later he lost power on arms and legs and ended up in hospital/ wound up losing power in his arms and legs and wound up on the floor". The patient was hospitalized for monoplegia (start date: Sep2021). Therapeutic measures were taken as a result of monoplegia.  Clinical Summary: As per agent, caller wanted to know if there were any preventive medicines for interactions caused by the Pfizer COVID-19 Vaccine. After caller was transferred, he mentioned he received the first two COVID-19 Vaccine doses on Mar2021 and was everything was fine, he had no problem. Then, on Sep2021 he received the booster and 24 hours later he lost power on arms and legs and ended up in hospital after (withheld) call and then he had to take some therapy. When caller was referred to his HCP, he mentioned that in one of the visits, he was told the booster reacts with immunological system and that his doctor said things that didn't made sense, and that he was actually medical misdiagnosed, which is common to happen to him. Term highlighted by reporter was yes.  Caller does not want to give name, was just asking for some information regarding booster shots, the Pfizer booster shot. Got 2 vaccines and had no reaction, to the regular ones. Unable to clarify specific name of Pfizer booster shot he was referring to. Sep2021, got booster shot and, wound up losing power in his arms and legs and wound up on the floor and getting (withheld) to go to the hospital. Knew people who have heart attacks from the shot. Has heard several people with recent immunization, who got the shot, had heart attacks. Caller did not have anything like that. Got the booster shot and was fine. 24 hours later, when he went to pick something up, couldn't get up off floor and lost all power in arms and legs. Asked if there was anything, other than not taking the booster that he could do, like medication or anything so he doesn't get a reaction. Clarified that he was asking if there was anything, like medication, he could take so he doesn't get a reaction to the booster.  No follow-up attempts are Possible; Information about lot/batch number cannot be obtained. No further information is expected.; Sender's Comments: Linked Report(s) : US-PFIZER INC-202201325062 Similar report from same reporter;US-PFIZER INC-202201326207 Same reporter/ patient/ event, different vaccine dose;