Skin in the areas of the rash began to feel prickly and irritated; Allergic red blotchy rash over most of the truck of my body, the sides of my neck, and my upper thighs; Skin in the areas of the rash began to feel prickly and irritated; Allergic red blotchy rash over most of the truck of my body, the sides of my neck, and my upper thighs; Allergic reaction; Allergic red blotchy rash over most of the truck of my body, the sides of my neck, and my upper thighs; Headache; Aching pain in my upper arm that spread through my shoulder and to my upper back; Aching pain in my upper arm that spread through my shoulder and to my upper back; Aching pain in my upper arm that spread through my shoulder and to my upper back; This spontaneous case was received on 21-Sep-2019 from other non-health professional via Agency (reference number: SEQW20-02003) and concerned a female patient of an unspecified age.  The patient's concurrent conditions included allergy to thimerosal and other preservatives. The patient's concomitant medications were not reported  On 15-Sep-2020 at 09:15 am, the patient was vaccinated with Fluad Quadrivalent (influenza vaccine, inactivated influenza virus surface antigen (subunit), egg-derived, MF59; dose: 0.5 ml, anatomical location, route of administration: not reported) for an influenza prophylaxis. The batch number and expiration date were unknown.  On the same day, less than 12 hours after receiving Fluad Quadrivalent vaccine, the patient had a severe headache and aching pain in her upper arm that spread through her shoulder and to her upper back.  On 17-Sep-2020, within 48 hours of receiving Fluad Quadrivalent vaccine, the patient developed an allergic red blotchy rash over most of the truck of her body, the sides of her neck and her upper thighs.   On the same day at 4:30 pm, the patient visited her doctor who confirmed that the patient was having an allergic reaction and advised her to take Benadryl (diphenhydramine hydrochloride) and Pepcid (famotidine) to reduce the effects.  On the same day, later that evening as reported, the patient's skin in the areas of the rash began to feel prickly and irritated by clothing brushing against it. The patient was advised to take Benadryl (diphenhydramine hydrochloride) topical cream which had been ordered.  At the time of initial reporting on 21-Sep-2020, the patient had not recovered from the events.  The reporter assessed the events as adverse reaction after receiving the Fluad (65+) vaccine.  The case was assessed as non-serious.  Company comment: A female patient of an unspecified age was administered Fluad Quadrivalent vaccine. On the same day, less than 12 hours after receiving Fluad Quadrivalent vaccine, the patient developed headache, pain in extremity, musculoskeletal pain and back pain. On 17-Sep-2020, within 48 hours of receiving vaccine the patient developed skin irritation, paraesthesia, rash macular, rash erythematous and dermatitis allergic. The patient visited her doctor who confirmed that the patient was having an allergic reaction and advised her to take Benadryl. The patient's concurrent conditions included allergy to thimerosal and other preservatives. More information regarding medical history and concomitant medications is needed. The case does not meet BC definition of anaphylaxis. However, causal role of the suspect vaccine is assessed as possibly related for all events.; Reporter's Comments: The reporter assessed the events as adverse reaction after receiving the Fluad (65+) vaccine.; Sender's Comments: A female patient of an unspecified age was administered Fluad Quadrivalent vaccine. On the same day, less than 12 hours after receiving Fluad Quadrivalent vaccine, the patient developed headache, pain in extremity, musculoskeletal pain and back pain. On 17-Sep-2020, within 48 hours of receiving vaccine the patient developed skin irritation, paraesthesia, rash macular, rash erythematous and dermatitis allergic. The patient visited her doctor who confirmed that the patient was having an allergic reaction and advised her to take Benadryl. The patient's concurrent conditions included allergy to thimerosal and other preservatives. More information regarding medical history and concomitant medications is needed. The case does not meet BC definition of anaphylaxis. However, causal role of the suspect vaccine is assessed as possibly related for all events.