Hallucinates; Extremely delusional; Paranoid; Agitated; Confused; tired; couldn't stand up; shrunk some; Booster; This is a spontaneous report received from a contactable consumer or other non hcp from medical information team.  A 79 year-old male patient received BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE), administration date 12Jan2022 (Batch/Lot number: unknown) at the age of 79 years as DOSE 3 (BOOSTER), SINGLE for COVID-19 immunisation, in the morning. Relevant medical history included: "Anca vasculitis" (unspecified if ongoing); "Allergies" (unspecified if ongoing). The patient has an autoimmune disease called Anca vasculitis, this disease affects his temporal lobe, and the small blood vessel area, oxygen doesn't get to his brain right, that affects his cognition, his symptoms look a lot like dementia, he has dementia symptoms. The autoimmune disease triggered everything after the vaccine. He has had this disease for 3 years now. The patient's concomitant medications were not reported. Vaccination history included: BNT162B2 (dose 1), administration date: 08Feb2021, when the patient was 78 years old, for COVID-19 immunization, reaction(s): "He was tired and slept it off"; BNT162B2 (dose 2), administration date: 02Mar2021, when the patient was 78 years old, for COVID-19 immunization, reaction(s): "Hallucinating", "paranoid", "agitated". The following information was reported: IMMUNISATION (medically significant) with onset 12Jan2022, outcome "unknown", described as "Booster"; HALLUCINATION (medically significant), outcome "unknown", described as "Hallucinates"; DELUSIONAL PERCEPTION (non-serious), outcome "unknown", described as "Extremely delusional"; PARANOIA (non-serious), outcome "unknown", described as "Paranoid"; AGITATION (non-serious), outcome "unknown", described as "Agitated"; CONFUSIONAL STATE (non-serious), outcome "unknown", described as "Confused"; FATIGUE (non-serious), outcome "unknown", described as "tired"; BALANCE DISORDER (non-serious), outcome "unknown", described as "couldn't stand up"; BODY HEIGHT DECREASED (non-serious), outcome "unknown", described as "shrunk some". The consumer (wife) reported that he got extremely delusional, hallucinates, he was paranoid and agitated. He got the booster yesterday, he woke up during the night, peed himself because he was so confused he couldn't get his pants down, he had been hallucinating. The consumer also reported that patient got the COVID booster yesterday. He was totally stable at first. She talked to him yesterday evening. He was tired, but he was fine. There was nothing cognitive going on. She got a call from her daughter this morning, that he was a mess. He peed on himself because he was so confused that he couldn't get his pants down. He couldn't get to the bathroom. He was hallucinating again. The daughter had put a call to the doctor, but none of the doctor's have information. They didn't know if it causes it or not. He had shrunk some. His current weight was 128-129 lbs. He used to weigh 139- 140 lbs, but the vasculitis caused problems with his weight. The daughter called her at 9 am, and was saying during the night he was having trouble going to the bathroom. He also got up early from 6-7 am. He was sleeping right now because he was really tired on top of it. The daughter was trying to get ahold of both of his doctors. The Nurse Practitioner couldn't get up with the neurologist. They were going to wait to discuss medications until tomorrow. That night he couldn't stand up. When he would try to walk he would fall. So he stopped that too. The events "hallucinates", "extremely delusional", "paranoid", "agitated" and "confused" were evaluated at the physician office visit and emergency room visit. Therapeutic measures were taken as a result of hallucination, delusional perception, paranoia, agitation, confusional state.  The lot number for bnt162b2 was not provided and will be requested during follow up.