Eye sight was getting worse; Big white spot that comes up on the image and that's not supposed to be there and it was quite large compared to what I have seen since last; This is a spontaneous report from a Pfizer sponsored program COVAX US Support.  A contactable 74-year-old female ritired nurse (patient) reported that she received second dose of BNT162b2 (PFIZER-BIONTECH COVID-19 VACCINE, Lot number EN6204) intramuscular into the right arm on 24Mar2021 (at the age of 73-year-old) at single dose for COVID-19 immunization. The patient had received the first dose of vaccine on 24Feb2021 (lot number EL9266) in the left arm. Concomitant Products included Vitamin C complex as supplement. Patient history included arthritis and had a H-pylori test done recently, because of some gastritis she had, because It was abnormal last year that's why they repeated it this year but she had not gotten the result yet. The patient had a history of a retinal vein occlusion in her right eye, and she had this for about 3 years. She used to go and visit her doctor every 5 weeks, she can only go every 31 days because of Medicare and so she has been going for like 3 years and sometime she needed an injection, sometime I don't. The patient reported that she got her second vaccine dose and the several weeks later she went to her eye doctor to get an injection (further not clarified unspecified product) in her eye and when they did that apparently so her eye sight was getting worse so the result was not good between her injections. She went to get her second Pfizer vaccine injection for Covid and that's was fine. She had a little bit of reaction (Further clarification unknown), nothing big, and then when she went last week she noticed they took picture, computer generated pictures. So, they have to describe and she saw the difference in image from the last time she went in. She looked at all her papers that she had. She got a print out of this picture every month. There was a big white spot that came up on the image and that's not supposed to be there and it was quite large compared to what she has seen since last time. That kind concerned her and it took her a while to think about this. Why had changed so drastically. So, the patient was not sure if that had anything to do with the vaccine or not. The doctor was not sure if that had anything to do with it. When she noticed it, the only thing that was different was that she got the Covid injection the second one. It may not have anything to do with that. I did call the doctor office and doctor said was probably because she had gone seven weeks between injections and he thought it was the length of time. She went may be 5 weeks or 6 weeks it might not have this been as big and that might have made a difference. Treatment taken in response to adverse events was reported as no.  The patient had just the shot she got in her eyes, the one shot couple of month she didn't have anything else. The outcome of the events was unknown.  No follow-up are needed, no further information is expected.; Sender's Comments: -Based on a the information in the case report and a plausible temporal relationship, A possible causal relationship between events Visual acuity reduced,Retinogram abnormal cannot beexcluded