creatine kinase was high; Caller states her hands and arms swelled up with her skin feeling tight; Forehead headaches; Caller states her hands and arms swelled up with her skin feeling tight; Fingers turning blue and purple; Acid reflux; Caller states that her face felt heavy, like her skin was tightening. Caller later states after a while the heaviness worsened./Caller states it all got worse; little sharp pain.; Caller states that she experienced itchiness on her face; Caller states that her face felt heavy, like her skin was tightening; Caller states she felt numbness on her face, which included tingling, pins and needles; Caller states she felt numbness on her face, which included tingling, pins and needles, and a little sharp pain; Caller states she had shoulder, neck and hip pain, on the left side; Caller states she had shoulder, neck and hip pain, on the left side; Caller states she had shoulder, neck and hip pain, on the left side; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP). The reporter is the patient.  A 40-year-old female patient received BNT162b2 (BNT162B2), on 21Dec2021 as dose 3 (booster), single (Lot number: FJ1611) at the age of 40 years for covid-19 immunisation; atorvastatin (ATORVASTATIN), from Dec2021 (Batch/Lot number: unknown) to Mar2022 at 20 mg 1x/day, oral for blood cholesterol increased. The patient's relevant medical history included: "high cholesterol" (unspecified if ongoing). The patient's concomitant medications were not reported. Vaccination history included: BNT162b2 (Vaccine Name: First Covid Vaccine, Lot Number: EN6208), administration date: 15Mar2021, when the patient was 39-year-old, for COVID-19 immunization; BNT162b2 (Manufacturer: Second Covid vaccine, Lot Number: EW0151), administration date: 06Apr2021, when the patient was 39-year-old, for COVID-19 immunization. The following information was reported: ARTHRALGIA (non-serious), NECK PAIN (non-serious), ARTHRALGIA (non-serious) all with onset Dec2021, outcome "not recovered" and all described as "Caller states she had shoulder, neck and hip pain, on the left side"; PARAESTHESIA (non-serious) with onset 23Dec2021, outcome "not recovered", described as "Caller states she felt numbness on her face, which included tingling, pins and needles"; HYPOAESTHESIA (non-serious) with onset 23Dec2021, outcome "not recovered", described as "Caller states she felt numbness on her face, which included tingling, pins and needles, and a little sharp pain"; SKIN TIGHTNESS (non-serious) with onset 23Dec2021, outcome "not recovered", described as "Caller states that her face felt heavy, like her skin was tightening"; CONDITION AGGRAVATED (non-serious) with onset 23Dec2021, outcome "not recovered", described as "Caller states that her face felt heavy, like her skin was tightening. Caller later states after a while the heaviness worsened./Caller states it all got worse"; PRURITUS (non-serious) with onset 23Dec2021, outcome "not recovered", described as "Caller states that she experienced itchiness on her face"; PAIN (non-serious) with onset 23Dec2021, outcome "not recovered", described as "little sharp pain."; GASTROOESOPHAGEAL REFLUX DISEASE (non-serious) with onset Jan2022, outcome "not recovered", described as "Acid reflux"; PERIPHERAL SWELLING (non-serious), PERIPHERAL SWELLING (non-serious) all with onset Jan2022, outcome "not recovered" and all described as "Caller states her hands and arms swelled up with her skin feeling tight"; CYANOSIS (non-serious) with onset Jan2022, outcome "not recovered", described as "Fingers turning blue and purple"; HEADACHE (non-serious) with onset Jan2022, outcome "not recovered", described as "Forehead headaches"; BLOOD CREATINE PHOSPHOKINASE INCREASED (non-serious), outcome "unknown", described as "creatine kinase was high". The events "caller states that she experienced itchiness on her face", "caller states that her face felt heavy, like her skin was tightening", "caller states she felt numbness on her face, which included tingling, pins and needles", "caller states she felt numbness on her face, which included tingling, pins and needles, and a little sharp pain", "forehead headaches", "caller states her hands and arms swelled up with her skin feeling tight", "fingers turning blue and purple", "acid reflux", "caller states that her face felt heavy, like her skin was tightening. caller later states after a while the heaviness worsened./caller states it all got worse", "little sharp pain.", "caller states she had shoulder, neck and hip pain, on the left side" and "creatine kinase was high" required physician office visit. Relevant laboratory tests and procedures are available in the appropriate section. The action taken for atorvastatin was unknown. Therapeutic measures were taken as a result of gastrooesophageal reflux disease.  Additional information: Caller states she is calling about the Pfizer Covid vaccine, booster number one. Caller states she took both Covid vaccines, then took her booster in Dec2021. Caller states she felt a lot of her effects about 2 days after her booster. Caller states her doctor did blood work, and it showed her creatine kinase was high, and this is a side effect of the medication. Caller states that she wants to add in Jan2022, her fingers turned blue and purple and she had acid reflux. She is just assuming it is from the Covid booster. Caller states that her doctor started her on Famotidine, for acid reflux. Caller states that it works for a few hours and it helps her symptoms, but then after awhile, she starts to burp again. Caller states it does not control her symptoms for the whole day. Caller states she takes 40mg tablet by mouth once a day. Prior Vaccinations (within 4 weeks) If applicable, list any other vaccinations within four weeks prior to the first administration date of the suspect vaccine(s): No. Family Medical History Relevant to AE(s): not provided. Caller cannot provide an NDC, Lot number or expiration date when probed, because the bottle is at home during the time of the call. Product strength and count size dispensed: she now has a 3 month supply . No additional lot numbers. Is a sample of the product available to be returned, if requested (Y/N): Caller is presently taking the medication. No packaging sealed and intact.   No follow-up attempts are possible. No further information is expected.