Fever; aching all over; Chills; Nausea; Injection site pain; This is a spontaneous report from a contactable nurse. This nurse reported for a 78-year-old male patient (husband) received second dose of BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, Formulation: Solution for injection, lot number and expiration date was not reported) via an unspecified route of administration, administered in Arm on 12Mar2021 (at the age of 78-years-old) as DOSE 2, SINGLE for COVID-19 immunization. Medical history included cardiac failure congestive, COVID-19 from Dec2020 to an unknown date, hypertension, diabetes mellitus, cardiac disorder, hospitalization, intestinal haemorrhage, myocardial infarction and chronic obstructive pulmonary disease from an unknown date and unknown if ongoing. Historical AE: COVID-19: She said her husband had been hospitalized and was sent home in the full blossom with it. She said her husband lost blood and no one knows why, and then he has heart attacks. She said that he lost blood from somewhere in his small intestine where there was a leak, also he has congestive heart failure, so they can't operate on him because they can't put him asleep. She said that they couldn't find the leak, and then he got COVID when he caught it at the hospital and they sent him home in an ambulance to her. Caller clarifies that her husband loses blood and has heart attacks because he did not have enough blood to keep him going. She said right now he was at an appointment to get an iron infusion he went to the hospital to get that. Other Medical Conditions: Caller said her husband's conditions were diagnoses 5-6 years ago, and they said COPD then other things which went on and on. She said it was at least 2-3 years, probably more, it has been a long time with a lot of battles and a lot of hospitalizations and emergencies. She said her husband lost blood and it affected his heart and his enzymes go down and he has chest pains and was short of breath and can't breathe. She said that her husband got COVID in December at (Name withheld). She said she kept him separate. She said that they were in the same house, it was cold with winter, the heat was running, so she got it too but not as bad as he did. She said that they both recovered before they got their vaccines. There were no concomitant medications. Patient had not had any other recent vaccinations or started any new medications. Patient had previously received first dose of BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, Formulation: Solution for injection, lot number and expiration date was not reported) via an unspecified route of administration on 19Feb2021 (at the age of 78-years-old) as DOSE 1, SINGLE for COVID-19 immunization. It was reported that, caller said she called about the Pfizer COVID-19 vaccine shot and said that her husband got two doses. She said her husband has to get blood and iron a lot for infusions, so she was reporting for him his side effects for the second shot. She said after the second shot her husband had a fever, was aching all over, he had chills so bad and a lot of nausea on an unspecified date in Mar2021. It was horrible for about 16-18 hours and then finally she was able to get him some Tylenol. Caller did not provide any further details about the Tylenol. She said her husband's second dose had the most side effects, thought they both had pain at the injection site on the arm muscle on an unspecified date, which she didn't think was a big deal as him. Caller said that her husband has a high tolerance for a lot, for all he has been through. She said her husband's his fever, aches, and chills the next day were pretty good day, and the next day he was more like himself. Therapeutic measures were taken as a result of AEs as patient received Tylenol. The outcome of events fever, aching all over and chills was resolved on an unspecified date in 2021. While the outcome of event injection site pain was not resolved and it was unknown for nausea.  No follow-up attempts are possible; information about lot/batch number cannot been obtained.