very severe side effects; pressure in her head, intense pressure in her head, feels like her head was going to explode; anxiety; depression; trigeminal neuralgia; pain settled in her left eye, pain all around her left eye and under that eye; eye doctor said it looks like floaters in her eyes; pressure in her left ears, ear pressure got really intensely bad; pressure settled in her left eye; Intense pressure in head; fatigue; This spontaneous case was reported by an other health care professional and describes the occurrence of ADVERSE REACTION (very severe side effects), HEAD DISCOMFORT (pressure in her head, intense pressure in her head, feels like her head was going to explode), OCULAR DISCOMFORT (pressure settled in her left eye), EYE PAIN (pain settled in her left eye, pain all around her left eye and under that eye) and EAR DISCOMFORT (pressure in her left ears, ear pressure got really intensely bad) in a 39-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     No Medical History information was reported.   On an unknown date, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On an unknown date, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 08-Jan-2021, the patient experienced OCULAR DISCOMFORT (pressure settled in her left eye), EAR DISCOMFORT (pressure in her left ears, ear pressure got really intensely bad), FATIGUE (fatigue) and HEADACHE (Intense pressure in head). On 09-Apr-2021, the patient experienced EYE PAIN (pain settled in her left eye, pain all around her left eye and under that eye) and VITREOUS FLOATERS (eye doctor said it looks like floaters in her eyes). On 10-May-2021, the patient experienced ANXIETY (anxiety), DEPRESSION (depression) and TRIGEMINAL NEURALGIA (trigeminal neuralgia). On an unknown date, the patient experienced ADVERSE REACTION (very severe side effects) and HEAD DISCOMFORT (pressure in her head, intense pressure in her head, feels like her head was going to explode). The patient was treated with PARACETAMOL (TYLENOL) at a dose of UNK dosage form; IBUPROFEN at a dose of UNK dosage form and METHYLPREDNISOLONE SODIUM SUCCINATE (SOLUMEDROL) on 10-May-2021 at a dose of 1000 mg. At the time of the report, ADVERSE REACTION (very severe side effects), HEAD DISCOMFORT (pressure in her head, intense pressure in her head, feels like her head was going to explode), OCULAR DISCOMFORT (pressure settled in her left eye), EYE PAIN (pain settled in her left eye, pain all around her left eye and under that eye), EAR DISCOMFORT (pressure in her left ears, ear pressure got really intensely bad), VITREOUS FLOATERS (eye doctor said it looks like floaters in her eyes), ANXIETY (anxiety), DEPRESSION (depression), FATIGUE (fatigue) and HEADACHE (Intense pressure in head) outcome was unknown.        For mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown), the reporter did not provide any causality assessments.   No Concomitant products were provided. No  treatment medications were Tylenol, ibuprofen and sulomedrol 1000mg Action taken with mRNA-1273 in response to events was not applicable.   This case was linked to MOD-2021-015514 (Patient Link).   Most recent FOLLOW-UP information incorporated above includes: On 04-May-2021: Reporter address was updated, patient demographics was updated On 26-May-2021: No new information On 27-May-2021: Significant Follow-up