PARALYZED/FROZEN TOES; SCAR ON KNEE STARTED SWELLING; SCAR ON KNEE PAINFUL; FOOT PAIN; TORN MENISCUS; FALL; TIGHTENING OF THE JAW/ PARALYZED/ FROZEN JAW; SWOLLEN ARM/ FOOT SWELLING; TENDER ARM; This spontaneous report received from a patient concerned a 57 year old White female. The patient's weight was 169 pounds, and height was 65 inches. The patient's past medical history included: scalp psoriasis, colon cancer, 18 inches of transverse colon removed, depression, lymph nodes removed (due to prior colon cancer surgery), abscess tonsil, freezing of jaw, fall, and past injuries on the left side, and concurrent conditions included: non-smoker, non-alcoholic, and scar on knee. The patient had no history of drug abuse or illicit drug usage. The patient was previously treated with citalopram for depression, bupropion hydrochloride for depression, omeprazole for depression; and experienced muscle spasms when treated with procaine hydrochloride for drug used for unknown indication, and drug allergy when treated with epinephrine.  The patient received covid-19 vaccine ad26.cov2.s (suspension for injection, route of admin not reported, batch number: 1805020, expiry: UNKNOWN) dose was not reported, 1 total, administered on right arm on 05-MAR-2021 at afternoon around 16:00 for prophylactic vaccination. No concomitant medications were reported.  On 08-MAR-2021, the patient experienced a small amount of swelling underneath the arm that was a little tender that started for 3-4 days and only lasted a couple of days. On 08-APR-2021, the patient started experiencing a tightening of the jaw, similar to temporomandibular pain. On 21-APR-2021, the patient's jaw was paralyzed/frozen. The patient could only fit a finger in the jaw. The patient visited emergency room on same day for the jaw and was not admitted. They ruled out infection, referred her to ENT and gave a shot for the pain. The surgery was recommended, but she preferred to due surgery. The scar on knee from the fall 15 years ago started swelling (was not too painful at the time and also given as knee pain and swelling). Her small toe and two toes in from the left became paralyzed (paralyzed/frozen toes). On 02-MAY-2021, she was in a lot of pain and started walking with a cane. Around 03-MAY-2021, her knee "ballooned out" and foot started swelling. She had visited her primary care physician, ENT, and orthopedic guy. The patient also had emergency room visit for the knee/foot on 03-MAY-2021. They ruled out clotting, rheumatoid arthritis and gout. They found inflammation markers and performed spinal tap and ultrasound. On 04-MAY-2021, the patient had DVT ultrasound, which ruled out clotting. At the end of MAY-2021, she took a fall and tore her meniscus. In JUL-2021, she had surgery to repair it. She was now doing rehab to help with the swelling and pain. All of the ailments affected her right side. The residual symptoms were pain in foot, right foot, pinky foot and next toe in had not woken up (still paralyzed). The action taken with covid-19 vaccine ad26.cov2.s was not applicable. The patient recovered from tightening of the jaw/ paralyzed/ frozen jaw, torn meniscus, scar on knee started swelling, and scar on knee painful, and tender arm on MAR-2021, had not recovered from paralyzed/frozen toes, and foot pain, and the outcome of swollen arm/ foot swelling and fall was not reported. This report was serious (Other Medically Important Condition).; Sender's Comments: V0:20210903197-JANSSEN COVID-19 VACCINE Ad26.COV2.S -paralyzed/frozen toes -This event(s) is considered unassessable. The event(s) has a compatible/suggestive temporal relationship, is unlabeled, and has unknown scientific plausibility. There is no information on any other factors potentially associated with the event(s).  V0:20210903197- JANSSEN COVID-19 VACCINE Ad26.COV2.S -torn meniscus -This event(s) is considered not related. The event(s) has a compatible/suggestive temporal relationship, is unlabeled, and has unknown scientific plausibility. There are other factors more likely to be associated with the event(s) than the drug medical history, underlying condition (fall )