the insertion of the medication was truly excruciating; headache; nausea; not feeling well; confused as to how to get home (less than 2 miles!); weak; full blown migraine; stayed in bed all day; This is a spontaneous report received from a contactable reporter(s) (Consumer or other non HCP). The reporter is the patient.  A 59 year-old female patient (not pregnant) received bnt162b2 (BNT162B2, solution for injection), administered in arm left, administration date 13Apr2021 09:45 (Lot number: EW0153) at the age of 59 years as dose 1, single for covid-19 immunisation. Relevant medical history included: "hashimotos thyroiditis" (unspecified if ongoing); "depression" (unspecified if ongoing); "sarcoid" (unspecified if ongoing), notes: sarcoid (lungs); "Known Allergies: CORN" (unspecified if ongoing); "Known Allergies: gluten" (unspecified if ongoing). The patient took concomitant medications. Past drug history included: Codeine, reaction(s): "Known Allergies: codeine". The following information was reported: WRONG TECHNIQUE IN PRODUCT USAGE PROCESS (non-serious) with onset 13Apr2021 10:00, outcome "recovering", described as "the insertion of the medication was truly excruciating"; HEADACHE (non-serious) with onset 13Apr2021 10:00, outcome "recovering", described as "headache"; NAUSEA (non-serious) with onset 13Apr2021 10:00, outcome "recovering", described as "nausea"; MALAISE (non-serious) with onset 13Apr2021 10:00, outcome "recovering", described as "not feeling well"; CONFUSIONAL STATE (non-serious) with onset 13Apr2021 10:00, outcome "recovering", described as "confused as to how to get home (less than 2 miles!)"; ASTHENIA (non-serious) with onset 13Apr2021 10:00, outcome "recovering", described as "weak"; MIGRAINE (non-serious) with onset 13Apr2021 10:00, outcome "recovering", described as "full blown migraine"; HYPOKINESIA (non-serious) with onset 13Apr2021 10:00, outcome "recovering", described as "stayed in bed all day". Therapeutic measures were not taken as a result of wrong technique in product usage process, nausea, malaise, confusional state, asthenia, hypokinesia. Therapeutic measures were taken as a result of headache, migraine.  Additional information: No other vaccine in four weeks. The patient had other medications in two weeks. The patient did not have covid prior vaccination. The patient was not tested for covid post vaccination. The needle insertion was fine, but the insertion of the medication was truly excruciating. Almost had him stop. Before she even left the store started developing headache and a little nausea. When got into car was not feeling well and was confused as to how to get home (less than 2 miles). When got home went straight to bed because felt weak and had headache. Headache worsened during the night (took Ibuprofen 800 mg). Had full blown migraine by 14th and stayed in bed all day. Took 2 doses of Rizatriptan on 14th and 1 dose this a.m. (15th). Finally feeling better, though still a little nauseous. Interestingly, arm not really ever sore, except if the patient pushed on area. Would not really even say had "sore arm" - but the insertion of the medication was excruciating.  No follow-up attempts are possible. No further information is expected.