She also used to have heat intolerance to almost any heat and it was horrible and that has also lessened since the second vaccine; Since her 2nd dose that has gone down to where she is not soaking wet a few times a day; She also thought that it was a little longer than 3 weeks between the vaccines; This is a spontaneous report from a contactable Other Health Professional (patient). A 77-year-old female patient received BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE), at same age, dose 2 via an unspecified route of administration on 20Apr2021 (Batch/Lot Number: EW0164) as DOSE 2, SINGLE for covid-19 immunisation. Medical history included tick bite and they found three parasites in her labs, Lyme, Babesia, and Ehrlickia from Jul2019, had a bruise about 2.5 inches wide around the front of her chest from Nov2019, FLU A (they did a nasal swab and she was positive for influenza A) from Jul2019, Lymes from Jul2019, Babesia from Jul2019, Ehrlickia from Jul2019, air hunger ("lung" side effects of chest tightness-which felt like her chest had been "wrapped with saran wrap), heat intolerance, sweating, ill/ sick and cut her finger. Concomitant medications included doxycycline; azithromycin (ZITHROMAX); cefuroxime axetil (CEFTIN [CEFUROXIME AXETIL]); and metronidazole (FLAGYL [METRONIDAZOLE]). The patient was received first dose of BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, Lot Number: EN6208) on 30Mar2021, at age of 77 years old, for covid-19 immunisation and experienced for specific symptoms she had been experiencing because of her tick bite had either resolved all together or lessened in severity and sweating have lessened in severity. On either 06Jul2019 or 07Jul2019 the caller was bitten by a tick and she was in the hospital on 29Jul2019 because of that tick bite and they found three parasites in her labs, Lyme, Babesia, and Ehrlickia. The patient had since been ill and her immune system hasn't been so hot for the last few years and she had been sick because of the tick bite. When she went in Nov2019 she had a bruise about 2.5 inches wide around the front of her chest and that's how she felt. The babesia affected red blood cells, like malaria, and the ehrlickia only eats plasma. She was sitting there for days and then noticed that it was gone after she had the COVID vaccine. She said that she never went to urgent care and she hadn't been to the emergency room since she was in her 30's and she cut her finger, and she knew better than that, but it was not a very pleasant experience. She said to them that she felt like she had the flu and they did a nasal swab and she was positive for influenza A and she keeps thinking about this and a correlation with Pfizer and she guesses that it went after and decided to kill that too. Patient stated that this nasal swab and situation just discussed was prior to the COVID vaccine, this occurred in Jul2019. She of course told them at the urgent care that it is Jul2019. After her 2nd shot (Apr2021), because she had malaria like symptoms but hers was not caused by mosquitos, in the beginning she would have profuse sweating. She was not quite diaphoretic but she was as close as she could be to that. Since her 2nd dose that has gone down to where she was not soaking wet a few times a day. She also used to have heat intolerance to almost any heat and it was horrible and that has also lessened since the second vaccine. She also thought that it was a little longer than 3 weeks between the vaccines. She couldn't give an exact date for when it stopped she just noticed that it was gone. It was not a drastic elimination and then it had taken a while for it go away completely. She confirmed that for both that sometime in Apr2021 her conditions were slowly lessened. She thought it was medically significant but maybe that was because it only applies to her, but she would like for it to apply to everyone else. Patient reporting AEs following the COVID vaccine and mentioned that from a previous tick bite she supposedly got all of the things that she was supposed to get in her medications and it was a horrible, thick, old medicine along with everything else. Probed for name of the medication that was horrible and thick and said declined to provide since she cannot remember. She knew that she had been on courses of things such as doxycycline, Zithromax, Ceftin, Flagyl, and whatever the other is for it was also for malaria. It was thick and old colored, it was 5 mg and she took it. She couldn't recall the name. That's what they use and they quinine and mix it with vodka. The outcomes of events were unknown. The heat intolerance that she has had and the sweating that she had are not as severe as they were before was considered as related.; Sender's Comments: A contributory role of the suspect drug cannot be excluded for events therapeutic response unexpected and hypohidrosis. The impact of this report on the benefit/risk profile of the Pfizer product is evaluated as part of Pfizer procedures for safety evaluation, including the review and analysis of aggregate data for adverse events. Any safety concern identified as part of this review, as well as any appropriate action in response, will be promptly notified to regulatory authorities, Ethics Committees, and Investigators, as appropriate.