Catatonic state; Suicidal ideation; Psychosis; This is a spontaneous report received from a contactable reporter(s) (Consumer or other non HCP). The reporter is the parent.  A 27-year-old male patient received BNT162b2 (BNT162B2), on 13Apr2021 as dose 2, single (Lot number: EW0162) at the age of 27 years for covid-19 immunisation. The patient's relevant medical history included: "Peanut allergy" (unspecified if ongoing), notes: severe peanut allergy; "Anxiety" (unspecified if ongoing). The patient's concomitant medications were not reported. Vaccination history included: BNT162b2 (Dose no.1, LOT: EN6207), administration date: 16Mar2021, when the patient was 27-year-old, for COVID-19 immunization, reaction(s): "Psychosis", "Paranoia".  The following information was reported: SUICIDAL IDEATION (caused and prolonged hospitalization, medically significant) with onset 13Apr2021, outcome "unknown"; PSYCHOTIC DISORDER (hospitalization) with onset Apr2021, outcome "unknown", described as "Psychosis"; CATATONIA (hospitalization) with onset Jan2022, outcome "unknown", described as "Catatonic state". The patient was hospitalized and prolonged hospitalization for suicidal ideation (start date: 13Apr2021, discharge date: 20Apr2021, hospitalization duration: 8 day(s)); for psychotic disorder (start date: 03May2022, discharge date: 10May2022, hospitalization duration: 8 day(s)). The patient underwent the following laboratory tests and procedures: Blood test: Unknown results; Gene type test: Unknown results, notes: That test showed that none of the medicines he was on have been good for him because he doesn't metabolize the medication effectively so there are very few that are ok for him. Therapeutic measures were taken as a result of psychotic disorder.  Clinical course: Patient had Other Conditions. Warm transfer from (name withheld). Calling about COVID19 vaccine. Her son got the vaccine way back in 2021 and had a severe reaction with psychosis and has been living in a nightmare for 2 years. Caller wants to report. She not only wants to report she wants to see about other cases. She has been to several doctors getting second opinions because what her son is experiencing would come out between ages 18-20 and he was 28 at the time. He was working 50 hours a week and never had psychosis. Her son has not worked since July and can't work and is on psychotic medication so he doesn't go into psychosis. He has been in and out of hospital 6 times over the past two years. The first psychosis came 2 weeks after first vaccine. On the date of the second vaccine he was suicidal the same day. Caller clarified that her son was 27-year-old when this started, not 28. He wouldn't go get another vaccine after what he experienced. Date of first psychosis was 11Apr2021. When her son got the second shot, caller was with him. They watched him longer because he has severe peanut allergy. About 10 minutes after second vaccine, he yelled I'm sorry. He ended up suicidal that night. He has never had history of psychosis or being suicidal. On 11Apr2021 he went to ER with symptoms of paranoia and psychosis. Second vaccine was on 13Apr2021 and he was admitted to hospital for suicidal ideation. In hospital from 13Apr2021-20Apr2021. He came out of hospital on Abilify and antidepressants. On 03May2021 he went to hospital again for more psychosis and stayed overnight. He went off meds in Oct2021. Caller clarified the medications her son went off of in Oct2021 were Abilify and antidepressants. In Jan2022 he was taken in and stayed overnight and was in catatonic state. He was released. On 11Feb2022 while visiting in another state, he was brought to the hospital with psychosis and catatonic state. They called it something, but she would have to look through papers. On 03May2022 he was in hospital again from 03May2022 until 10May2022 for same thing psychosis. The most recent hospitalization was from 11Oct2022 until 20Oct2022. That was the worst of this. After he was released, he went to acute care. Since then he has been on antipsychotic medication which he does not like. He has not been able to work since Jul2022. He was back and forth with job after the first vaccine but wasn't able to work. It was on and off, not full time by any means. Prior to the vaccine he was working 50 hours and wouldn't call in sick. Now there has been a total transition. He was just put on Medicaid. He had been paying his own insurance until Jan2023, then got withheld. Now with that he is getting worst care for mental health than he was with his own insurance. It has been a nightmare. Abilify and antidepressants, Her son didn't feel well on those medications. It was hard to be on those medications when he was not normally on medication. He was on anti-anxiety medication in college. He always had anxiety, but never psychosis. Antipsychotic Medication: he gets injection once a month. Caller has been pleading him to stay on it until they figure it out. Caller doesn't want to see him having psychosis. He did have a gene type test done. That test showed that none of the medicines he was on have been good for him because he doesn't metabolize the medication effectively so there are very few that are ok for him. What he is on now, the antipsychotic, he should be ok on it. The gene type test tells them that. That is why the ones he was on in the past weren't working for him. Caller clarified the medication her son was on in the past as Abilify and antidepressants. The doctor said she never saw someone that doesn't metabolize the medicine correctly. Her son did go for second opinion. Caller has been talking to people. The nurse at the acute care mentioned another girl about caller's son's age had the scenario after the COVID-19 vaccine. Someone else said the same thing. There are some cases, but caller doesn't know how many. Her son is not the first case this has happen to. Caller Doesn't know the girl patient. Caller wished she did know the girl so she could ask what that girl is doing to help her. Caller doesn't know how long her son can stay on the medicine and if he can get back to work. He went to withheld school and he worked in kitchen with knives. Caller doesn't know if he is capable of doing that. Concomitant Medication: None. He didn't take medication, he only took vitamins previously. There are 3 ways to have psychosis. Her son had one MRI without contrast and blood work. Went to hospital on the 11Apr2021 and went to doctor on 12Apr2021. Then on 13Apr2021 he ended up in hospital and was suicidal that night. Intensive Care Unit: none, he was in mental health crisis. Description of complaint: Admitted to hospital for suicidal ideation. He came out of hospital on Abilify and antidepressants. On 03May2021 he went to hospital again for more psychosis and stayed overnight. Had a gene type test done. That test showed that none of the medicines he was on have been good for him because he doesn't metabolize the medication effectively. That is why the ones he was on in the past weren't working for him. Caller clarified the medication her son was on in the past as Abilify and antidepressants.   No follow-up attempts are possible. No further information is expected.