guillain barré syndrome; other neurologic symptoms; twitching in feet top of feet; numbness in hands and feet; vertigo; joint stiffness; heart pounding; vision in right eye is blurry; face, arm and leg tightness; arthritic symptoms in hands and feet; chest pain; Initial information received on 06-Dec-2022 regarding an unsolicited valid  serious case received from a  patient and Non health care professional.   This case involves a 51 years old female patient who experienced guillain barré syndrome, other neurologic symptoms, twitching in feet top of feet, numbness in hands and feet, vertigo, joint stiffness, heart pounding, vision in right eye is blurry, face, arm and leg tightness, arthritic symptoms in hands and feet and chest pain after receiving vaccine Influenza quadrival a-b vaccine [fluzone qiv].  The patient's past vaccination(s) included Shingrix in Jan-2022. The patient's past medical history, medical treatment(s) and family history were not provided.  On 04-Nov-2022, the patient received a suspect Influenza quadrival a-b vaccine(Dose- 0.5mL)(Frequency- Once)( Strength = standard )(Formulation- Suspension for injection) (Batch/lot number-UJ943AA) via intramuscular route in the left arm.(expiry date: not reported) for Immunization  On 07-Nov-2022 the patient developed a serious event guillain barré syndrome (guillain-barre syndrome)(Latency- 3 days)following the administration of Influenza quadrival a-b vaccine.   On 07-Nov-2022 the patient developed a non-serious events other neurologic symptom (neurological symptom), twitching in feet top of feet (muscle twitching), numbness in hands and feet (hypoaesthesia), vertigo, joint stiffness, heart pounding (palpitations), vision in right eye is blurry (vision blurred), face, arm and leg tightness (muscle tightness), arthritic symptoms in hands and feet (arthritis) chest pain, following the administration of Influenza quadrival a-b vaccine.(Latency -3 Days)  Relevant laboratory test results included: Chest X-ray - On an unknown date:  [Saw doctors on 14NOV2022.( Ear, Eye and Throat doctor and PCP) has had an MRI, eye exam, chest x-ray, EKG],Electrocardiogram ,Magnetic resonance imaging, Ophthalmological examination.  Action taken: Not applicable.  An Ear, Eye and Throat doctor and PCP) has had an MRI, eye exam, chest x-ray, EKG, no medications. Was received as corrective treatment for the events  At time of reporting, the outcome was Not Recovered / Not Resolved for all events  Seriousness Criteria: Medically Significant for event guillain barré syndrome.; Sender's Comments: Sanofi Company Comment dated 06-Dec-2022  : This case involves a 51 years old female patient who experienced guillain barré syndrome, other neurologic symptoms, twitching in feet top of feet, numbness in hands and feet, vertigo, joint stiffness, heart pounding, vision in right eye is blurry, face, arm and leg tightness, arthritic symptoms in hands and feet and chest pain after receiving vaccine Influenza quadrival a-b vaccine [fluzone qiv].Based upon the reported information, the role of a vaccine cannot be assessed. However, lack of information of past and concomitant medication,any family history ,any concurrent conditions  precludes comprehensive case assessment