he may have had chills that night.; The initial case was missing the following minimum criteria: ICH-unspecified AE. Upon receipt of follow-up information on (14Oct2022), this case now contains all required information.  This is a spontaneous report received from contactable reporter(s) (Nurse) from medical information team, Program ID. The reporter is the patient.  A 67-year-old male patient received BNT162b2 (BNT162B2), on 11Feb2021 as dose 1, single (Lot number: EN9581) at the age of 67 years for covid-19 immunisation. The patient's relevant medical history included: "aortic stenosis" (unspecified if ongoing), notes: he had aortic stenosis, an occlusion causing problems.; "diastolic disfunction" (unspecified if ongoing), notes: He takes some medication for his heart, for weak heart, diastolic disfunction.; "weak heart/ heart issue" (unspecified if ongoing); "cholesterol" (unspecified if ongoing), notes: On cholesterol drug; "smoking" (unspecified if ongoing), notes: States he started the Bupropion after all of this happened. It's for smoking.; "blood pressure crisis" (unspecified if ongoing), notes: He was having blood pressure crisis a few months back and got on extra blood pressure medications. Concomitant medication(s) included: BUPROPION taken for ex-tobacco user; ALLOPURINOL; BABY ASPIRIN. Vaccination history included: Flu shot (He is sensitive to any flu shot anyways but not like this.), reaction(s): "sensitive"; Had tons of shots (Had every vaccination known to man.); Plague (He got a little reaction because he got 5 in 1 shot and they were all different, the plague, typhoid the whole 9 years), reaction(s): "reaction"; Typhoid (He got a little reaction because he got 5 in 1 shot and they were all different, the plague, typhoid the whole 9 years), reaction(s): "reaction"; Flu shot, reaction(s): "gets a little chill". The following information was reported: CHILLS (non-serious) with onset 11Feb2021, outcome "unknown", described as "he may have had chills that night.". Relevant laboratory tests and procedures are available in the appropriate section.  Additional information: Patient had received two shot original vaccine and both boosters. He was considering getting the Omicron booster. His concern was he had a progressively strong response from each shot. The last one caused him to be in bed for three days and did not feel good for about a week. His point was being as the variants are somewhat weaker and oral treatments are available would he be foolish to assume that he may be sufficiently protected and if there were other alternatives available. He had questions about Paxlovid and side effects but didn't mention if he was prescribed, they were general questions. He was a medic in the army and was licensed as an LPN, he went to specialty school in the army and got accredited and took the test. License is not currently active.  He state that with shot number 1 he was pretty asymptomatic, he may have had chills that night. Anytime he got the flu shot, he gets a little chill but it was never a problem. His shot #2, he was quite under the weather for a day and a half. For shot #3, he was somewhat feeling worse a couple days but cleared up and felt 100% in about 3 days and then for shot #4, he was in bed 3 days pretty much and didn't feel 100% for a week. His concern was where was that going. If it wasn't progressive, if it was the same response every time it wouldn't concern him. He was not afraid to get omicron one but considering why would he take the chance of 3-4 days in bed sick when he could just take oral medication if he comes down with it, he wouldn't be worse off.  His wife tested positive for COVID and was asymptomatic and they slept together forever. He never tested positive, and he had been exposed a couple other times and if he ever had it was very mild or he was asymptomatic. One more caveat with Paxlovid, he took some medication for his heart, for weak heart, diastolic disfunction. Last Nov he had catheter and they installed in the aortic well, it's an artificial valve they put in through a catheter through the femoral artery. He was in and out of the hospital and was there 1 night. They have not used this on younger people, he had aortic stenosis, an occlusion causing problems. He felt good but it sounded crazy, but he did hear there were interactions between some heart medications and Paxlovid and was not sure if they were rumor. He takes a couple of different blood pressure medications. He wouldn't have any trouble not using them for a week, he doesn't know. He could probably ask his family physician and suspects he would lay this all out and he will say it's up to him. He was not really looking for strong answers, just trying to sort through. What has got him disturbed was having worse reactions, as progresses more robust reactions. If he was going to be sick 3-5 days he may as well take a chance, he had been exposed. Knows we are not going to say yes take it or no don't take it. He was trying to establish some kind of level of risk. He was just looking to hear if anyone else is having these problems or if we recommend not taking. It's just the response he has, it's not an allergic reaction. In medical sense he was sure it would be labeled as mild reaction but to him it's more toward moderate more like flu. He was sensitive to any flu shot anyways but not like this. After the 4th dose Pfizer COVID 19 vaccine it was about hardest part of it, he doesn't know if he was sick a little earlier. With the other 3 it was about 12 hours after getting the vaccine and the last one may have been 6-8 hours after. It definitely started improving after 3 days and he felt 100% after a week. He was not afraid to get the Omicron, just trying to weigh it out if he should get it or if it's not worth it. For concomitant medication, he takes several every day including a few blood pressure medications, allopurinol, cholesterol drug, baby aspirin and he just started taking Bupropion. Stated he started the Bupropion after all of this happened. It's for smoking but he was having blood pressure crisis a few months back and got on extra blood pressure medications and gave him a script for that and it made him calm a little. Declined to provide further details. He would assume that someone would flag his profile if he was getting an interaction and he got a couple through the pharmacy, and no one said anything about interaction. For medical condition, just the heart issue. Had the procedure on 29Nov2021. He had Flu vaccine. The last 2 he got were for old timers, the bivalent for seniors. Has had every vaccination known to man. Was in (withheld) and had tons of shots, got every shot you could think of. He got a little reaction because he got 5 in 1 shot and they were all different, the plague, typhoid the whole 9 years. States nothing reportable or to be concerned about. He had signed up for flu shot and omicron shot when he got there, they said flu but not Omicron their vaccine got too warm. He mentioned really and truly he got a reaction and was glad it was not both at once. That it might not be bad to wait a couple weeks. The progression of the shot's response had him a little troubled, some people say it's a good thing. He was still looking for data and will contact his family physician. There were no real answers, but this been couple years so someone should. He had sent an email asking were there other alternatives like a lower dose. Apparently, he is the only guy complained about this, it's not offered to ease symptoms for anyone. He will talk over this with family physician. Caller declined a transfer to agent, he doesn't think it's an allergic reaction or anything like that, just a progression of severity is his main concern and he is weighing about other options. Will contact his healthcare provider.