blood pressure was 116/69, which was pretty low for her; last night when she had checked her blood pressure it was 180/90; she feels like she was hit by a truck; all she wanted to do was lay down and go to bed; she didn't feel good yesterday; walking really funny; didn't want to eat; had no interest in anything, like watching TV; all she wanted to do was lay down and go to bed; Joint pain; Muscle pain; her left shoulder really started to hurt; This is a spontaneous report from a contactable nurse(patient).   A 84-years-old female patient received BNT162B2(PFIZER-BIONTECH COVID-19 mRNA VACCINE, Solution for injection; Lot number and Expiration date: Not reported), dose 1 via an unspecified route of administration, administered in arm left on 08Mar2021 10:30 as 1st dose, single dose for COVID-19 immunization. No prior Vaccinations within 4 weeks. Medical history included diagnosed with Congestive heart failure a couple of years ago(ongoing) and she had been taking several blood pressure medicines for Congestive heart failure and had a shoulder replacement in the past. Back in Sep2020 patient blood pressure was down to 40/30 and she could hardly hold head up and she had to go to the hospital and be admitted. The patient's concomitant medications were not reported. On 08Mar2021, the patient left shoulder really started to hurt in the night. and on 09Mar2021, patient was not feeling good and her pain got really bad (joint and muscle pain), she told herself that she had to get to bed. She said she was really hurting, clarifying she had both joint and muscle pain. Every time patient moved she was crying and screaming from the pain. Her blood pressure had dropped. Patient said she knows her blood pressure gets very high with pain. Patient blood pressure medications can drop her blood pressure too fast, and too low. The patient underwent lab tests and procedures which included blood pressure measurement: her blood pressure was dropped to 116/69 mmhg, which was pretty low for her. She said last night when she had checked her blood pressure it was 180/90 mmhg. Patient was walking really funny, and hoped she did not fall. She was not interested in eating and She had no interest in anything, like watching TV all she wanted to do was lay down and go to sleep. On 10Mar2021, She feels like she was hit by a truck. It was reported on 09Mar2021(last night), things got worse; events left shoulder really started to hurt, did not feel good, joint pain and muscle pain was worsened. Patient reported she did not have a headache. She had been laying on her couch the whole time. Therapeutic measures were taken with 2 Tylenol PM 500mg (1000mg total) last night(09Mar2021) and again this morning(10Mar2021) but it did not work. Relatedness of drug to reactions/events was reported. No Investigation Assessment. The outcome of the events Joint pain, muscle pain, left shoulder really started to hurt and she didn't feel good yesterday was not recovered and other events was unknown.; Sender's Comments: Based on the temporal relationship and the information provided, A possible contributory role of the suspect product to the development of shoulder pain,malaise, gait disturbance, myalgia, decreased appetite, decreased interest and arthralgia cannot be excluded. The impact of this report on the benefit/risk profile of the Pfizer product is evaluated as part of Pfizer procedures for safety evaluation, including the review and analysis of aggregate data for adverse events. Any safety concern identified as part of this review, as well as any appropriate action in response, will be promptly notified to Regulatory Authorities, Ethics Committees and Investigators, as appropriate.