A couple of hives on the same arm of the injection between her wrist and elbow; A couple of hives on the same arm of the injection between her wrist and her elbow which were a little itchy/became more pronounced and spread to a larger area on both arms; Felt significantly more pain/felt like someone put a lit match on her arm and it burned so badly; This spontaneous case was reported by a consumer and describes the occurrence of URTICARIA (A couple of hives on the same arm of the injection between her wrist and elbow), PRURITUS (A couple of hives on the same arm of the injection between her wrist and her elbow which were a little itchy/became more pronounced and spread to a larger area on both arms) and VACCINATION SITE PAIN (Felt significantly more pain/felt like someone put a lit match on her arm and it burned so badly) in a 65-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 057M21A, 071F21A, 613A21A and 024M20A) for COVID-19 vaccination.     No Medical History information was reported.   On 10-Feb-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 10-Mar-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 29-Oct-2021, received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 15-Apr-2022, received fourth dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 15-Apr-2022,  after starting mRNA-1273 (Moderna COVID-19 Vaccine), the patient experienced VACCINATION SITE PAIN (Felt significantly more pain/felt like someone put a lit match on her arm and it burned so badly). On 17-Apr-2022, the patient experienced URTICARIA (A couple of hives on the same arm of the injection between her wrist and elbow) and PRURITUS (A couple of hives on the same arm of the injection between her wrist and her elbow which were a little itchy/became more pronounced and spread to a larger area on both arms). The patient was treated with DIPHENHYDRAMINE HYDROCHLORIDE (BENADRYL [DIPHENHYDRAMINE HYDROCHLORIDE]) at an unspecified dose and frequency. On 15-Apr-2022, VACCINATION SITE PAIN (Felt significantly more pain/felt like someone put a lit match on her arm and it burned so badly) had resolved. At the time of the report, URTICARIA (A couple of hives on the same arm of the injection between her wrist and elbow) and PRURITUS (A couple of hives on the same arm of the injection between her wrist and her elbow which were a little itchy/became more pronounced and spread to a larger area on both arms) had not resolved.            No concomitant medications were reported.  It was reported that hives and itchiness went away within 30 minutes. Reporter stated that the next day or 2 these became more pronounced and spread to a larger area on both arms and was recurring up until the day of report, usually lasting 30 minutes to a half an hour each time. Patient took Benadryl for some of these symptoms, but not very regularly.  It was reported that the patient has not had any changes to her diet, detergents, or medications.   This case was linked to MOD-2022-555540, MOD-2022-555535, MOD-2022-555537 (Patient Link).