Burning, tightness, some swelling around eye lids; I lost eye brows and lashes/eventually her eyebrows and eyelashes started to come out; Skin began to peel and flake; Burning, tightness, some swelling around eye lids; Burning, tightness, some swelling around eye lids/eyelids, face, and above her eyebrows were swollen; Face and neck turned blotchy red, it's like a rash all over/had redness that extended to her neck and collarbone; Very itchy, neck/Her neck was mostly itchy; Tried putting moisturizer and it burned/Her face did not itch as much but started to when it was peeling.; It feels like when you have a sunburn; Face and eye lids are pilling; courter size pink mark in the injection site; Face and neck turned blotchy red, it's like a rash all over; Felt mildly nauseous; mild pain in injection site; Mild fatigue; they noticed that her scalp was flaky; on her face, her eyelids felt tight as if she got burnt,; This spontaneous case was reported by a nurse (subsequently medically confirmed) and describes the occurrence of ERYTHEMA (Face and neck turned blotchy red, it's like a rash all over/had redness that extended to her neck and collarbone), PRURITUS (Very itchy, neck/Her neck was mostly itchy), BURNING SENSATION (Tried putting moisturizer and it burned/Her face did not itch as much but started to when it was peeling.), SUNBURN (It feels like when you have a sunburn) and ADVERSE EVENT (Face and eye lids are pilling) in a 58-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 013L20A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     The patient's past medical history included COVID-19 in April 2020. Concurrent medical conditions included Hypertension since 25-Nov-2019, Hyperlipidemia, Osteopenia and Drug allergy (PCN, Clindamycin, Bactrim, Avelox, Ketek). Concomitant products included SIMVASTATIN and FISH OIL for Hyperlipidemia, LISINOPRIL for Hypertension, VITAMIN D3 for Osteopenia.    On 21-Jan-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 29-Jan-2021, the patient experienced SKIN EXFOLIATION (they noticed that her scalp was flaky), SKIN TIGHTNESS (on her face, her eyelids felt tight as if she got burnt,) and FATIGUE (Mild fatigue). On 30-Jan-2021, the patient experienced ERYTHEMA (Face and neck turned blotchy red, it's like a rash all over/had redness that extended to her neck and collarbone), PRURITUS (Very itchy, neck/Her neck was mostly itchy), BURNING SENSATION (Tried putting moisturizer and it burned/Her face did not itch as much but started to when it was peeling.), SUNBURN (It feels like when you have a sunburn), ADVERSE EVENT (Face and eye lids are pilling), INJECTION SITE DISCOLOURATION (courter size pink mark in the injection site), RASH (Face and neck turned blotchy red, it's like a rash all over) and VACCINATION SITE PAIN (mild pain in injection site). 30-Jan-2021, the patient experienced NAUSEA (Felt mildly nauseous). On 31-Jan-2021, the patient experienced SKIN TIGHTNESS (Burning, tightness, some swelling around eye lids) and EYELID OEDEMA (Burning, tightness, some swelling around eye lids/eyelids, face, and above her eyebrows were swollen). On 03-Feb-2021, the patient experienced SKIN EXFOLIATION (Skin began to peel and flake). On 04-Feb-2021, the patient experienced MADAROSIS (I lost eye brows and lashes/eventually her eyebrows and eyelashes started to come out). On an unknown date, the patient experienced EYELID IRRITATION (Burning, tightness, some swelling around eye lids). At the time of the report, ERYTHEMA (Face and neck turned blotchy red, it's like a rash all over/had redness that extended to her neck and collarbone), PRURITUS (Very itchy, neck/Her neck was mostly itchy), BURNING SENSATION (Tried putting moisturizer and it burned/Her face did not itch as much but started to when it was peeling.), SUNBURN (It feels like when you have a sunburn), ADVERSE EVENT (Face and eye lids are pilling), INJECTION SITE DISCOLOURATION (courter size pink mark in the injection site), EYELID IRRITATION (Burning, tightness, some swelling around eye lids), SKIN TIGHTNESS (Burning, tightness, some swelling around eye lids), EYELID OEDEMA (Burning, tightness, some swelling around eye lids/eyelids, face, and above her eyebrows were swollen), SKIN EXFOLIATION (Skin began to peel and flake), MADAROSIS (I lost eye brows and lashes/eventually her eyebrows and eyelashes started to come out), SKIN EXFOLIATION (they noticed that her scalp was flaky), SKIN TIGHTNESS (on her face, her eyelids felt tight as if she got burnt,), RASH (Face and neck turned blotchy red, it's like a rash all over), FATIGUE (Mild fatigue), NAUSEA (Felt mildly nauseous) and VACCINATION SITE PAIN (mild pain in injection site) outcome was unknown.        The action taken with mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) was unknown.   For mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular), the reporter did not provide any causality assessments.   The patient tried moisturizer and it burned so she took it off.   On 30-jan-2021, the patient was advised to take Benadryl 50mg every 6 hours, but makes her very sleepy so patient started Steroid pack.  On 03-feb-2021, the patient called her PCP and was prescribed with a Medrol pack. On fourth day of the Medrol pack, the redness subsided but other events continued. By the end of the Medrol pack, the patient reports following events subsided : the peeling and flaking, including face, eyes lips; and eye brows and lashes.  The patient was prescribed with hydrocortisone ointment, a facial cleanser and lotion, vanicream, fluticasone lotion for scalp.  The patient referred to a physician and was prescribed with Steroid pack for 6 days and steroid ointment for the reported events.  The patient feels better after taking steroid pack and steroid ointment.   This case was linked to MOD-2021-142084 (Patient Link).   Most recent FOLLOW-UP information incorporated above includes: On 16-May-2021: Completed ADR form. On 18-May-2021: Updated additional follow up events, allergy, and treatment medications.