I have enlarged lymph nodes in my chest and abdomen all on the left side.; severe pain throughout my chest radiating down left arm and thought it was a heart attack; BP was high; I had severe pain especially in the retroperitoneal lymph node/pain in my lymph nodes; The lymph nodes in my chest, thoracic , back and pelvic area are very inflamed.; terrible upper respiratory infection; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP), Program ID. The reporter is the patient.  A 68-year-old female patient (not pregnant) received BNT162b2 (BNT162B2), on 18Apr2022 at 12:00 as dose 4 (booster), single (Lot number: FM0698) at the age of 68 years, in left arm for covid-19 immunisation. The patient's relevant medical history included: "Osteoarthritis" (unspecified if ongoing); "mild asthma" (unspecified if ongoing); "PTSD" (unspecified if ongoing); "known allergies: SULFA." (unspecified if ongoing); "known allergies: PCN" (unspecified if ongoing). The patient's concomitant medications were not reported. Vaccination history included: Bnt162b2 (Other Vaccine same date product=Pfizer , Other Vaccine same date lot number=30145BA, Other Vaccine same date dose number=3, Other Vaccine same date vaccine location=Left arm), for Covid-19 immunization; Bnt162b2 (Other Vaccine same date product=Pfizer , Other Vaccine same date lot number=EL9265, Other Vaccine same date dose number=2, Other Vaccine same date vaccine location=Left arm), for Covid-19 immunization; Bnt162b2 (Other Vaccine same date product=Pfizer , Other Vaccine same date lot number=EL8982, Other Vaccine same date dose number=1, Other Vaccine same date vaccine location=Left arm), for Covid-19 immunization. The following information was reported: HYPERTENSION (hospitalization) with onset 26Aug2022 at 12:00, outcome "recovering", described as "BP was high"; LYMPH NODE PAIN (hospitalization) with onset 26Aug2022 at 12:00, outcome "recovering", described as "I had severe pain especially in the retroperitoneal lymph node/pain in my lymph nodes"; LYMPHADENOPATHY (hospitalization) with onset 26Aug2022 at 12:00, outcome "recovering", described as "I have enlarged lymph nodes in my chest and abdomen all on the left side."; LYMPHADENITIS (hospitalization) with onset 26Aug2022 at 12:00, outcome "recovering", described as "The lymph nodes in my chest, thoracic , back and pelvic area are very inflamed."; CHEST PAIN (hospitalization) with onset 26Aug2022 at 12:00, outcome "recovering", described as "severe pain throughout my chest radiating down left arm and thought it was a heart attack"; UPPER RESPIRATORY TRACT INFECTION (hospitalization) with onset 26Aug2022 at 12:00, outcome "recovering", described as "terrible upper respiratory infection". The patient was hospitalized for lymphadenopathy, chest pain, hypertension, lymph node pain, lymphadenitis, upper respiratory tract infection (hospitalization duration: 1 day(s)). The events "i have enlarged lymph nodes in my chest and abdomen all on the left side.", "severe pain throughout my chest radiating down left arm and thought it was a heart attack", "bp was high", "i had severe pain especially in the retroperitoneal lymph node/pain in my lymph nodes", "the lymph nodes in my chest, thoracic , back and pelvic area are very inflamed." and "terrible upper respiratory infection" required physician office visit and emergency room visit. The patient underwent the following laboratory tests and procedures: Biopsy: (unspecified date) retroperitoneal lymph node indicated no cancer; Positron emission tomogram: (unspecified date) my lymph nodes were like 10 times the size t; SARS-CoV-2 test: (02Sep2021) Negative, notes: covid test type post vaccination=Nasal Swab. Therapeutic measures were taken as a result of lymphadenopathy, chest pain, hypertension, lymph node pain, lymphadenitis, upper respiratory tract infection.  Clinical course: In August Patient had severe pain throughout chest radiating down left arm and thought it was a heart attack. BP was high so took medication for that now. Heart is fine EF 65. PET scan revealed lymph nodes were like 10 times the size they're supposed to be and had severe pain especially in the retroperitoneal lymph node. The lymph nodes in chest, thoracic, back and pelvic area are very inflamed. Biopsy of retroperitoneal lymph node indicated no cancer. In the meantime, patient had a terrible upper respiratory infection, and was given a Z-Pak to treat that all the while still having pain in lymph nodes. A week later, the doctor gave me a methyl prednisone pack to take. Patient feel fantastic and the pain is gone. The oncologist recommended patient do not receive any more vaccinations at this time. Wanted to report this to Pfizer.