Being tired; Aches in the shoulder; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP). The reporter is the patient.  A 60 year-old male patient received bnt162b2 (BNT162B2), administered in arm left, administration date 25Jun2021 (Lot number: EW0181, Expiration Date: Aug2021) at the age of 59 years as dose 1, single for covid-19 immunisation. Relevant medical history included: "Blood pressure high" (unspecified if ongoing); "Allergy" (unspecified if ongoing), notes: He got a patch test done after high school at age 24 or 25- year-old, he was out of high school they did a allergy test on his back and he was allergic to Nickel.; "Water retention" (unspecified if ongoing); "Shoulder issues" (unspecified if ongoing), notes: Shoulder issues; "Ear issues" (unspecified if ongoing), notes: Ear issues. Concomitant medication(s) included: LOSARTAN POTASSIUM; HYDROCHLOROTHIAZIDE taken for fluid retention, blood pressure measurement, administration date Jun2021. Past drug history included: Allergies: ciprofloxacin, reaction(s): "Allergies: ciprofloxacin"; Allergies: amoxicillin, reaction(s): "Allergies: amoxicillin"; Allergic to nickel, reaction(s): "allergic to Nickel". The following information was reported: FATIGUE (non-serious) with onset 2021, outcome "unknown", described as "Being tired"; ARTHRALGIA (non-serious) with onset 2021, outcome "unknown", described as "Aches in the shoulder".  Additional Information: Patient states that he is calling about the COVID-19 Vaccine. He had the first and second dose in #. With the first 2 vaccines, there were issues and some Side effects but nothing serious. He then had the booster in Jan2022. He had a issue that he's never had before and got concerned. He is going to see his Ear, Nose and Throat doctor (ENT Doctor), he is seeing the ENT doctor next Wednesday, he is having it in the left ear, he's also got a left shoulder thing in which it feels like ants are running up the side of his shoulder, up into the neck and left ear. They looked at him in urgent care and said his Blood pressure was fine, all the stats were fine, but he is still getting this issue, its not continuous, it's occasional, but today it happened 6 times, it comes and goes, he's never had that before. He's not an anti vaxxer, he is actually glad he got the shot, he is pleased, he works with lots of people. He is going to find out next Wednesday with the ENT doctor what's going on with the ear. When he went to urgent care last week, the doctor couldn't see the inner ear because it was swollen, he's never had that happen before. He took the day off from work, and has missed 3-4 days of work because of this, he's got to get something done, he can't work with way his arm is, the left arm, he then clarified it's not the arm, its just the shoulder really. It's a buggy feeling crawling up. His blood pressure and pulse are fine. That's why he called, he is concerned, after the first and second shot it wasn't a big deal, but he has had this after the 3rd dose on 29Jan2022. . Concomitant Medication: He's not on anything new, he is taking the blood pressure medication Hydrochlorothiazide, he was prescribed last year. In changes along the time of the shots, he recalls that he was put off of losartan potassium prior to the first dose. He was put on Hydrochlorothiazide some time in Jun2021. Caller clarified that Losartan potassium was stopped in Jun2021 and hydrochlorothiazide was started. He adds that after the first shot, there was no problem but aches in the shoulder and being tired. With the Second shot he got lethargic, slept all day, he was exhausted, wipe out, he had pain in the shoulder but didn't get sick or have a fever, he just got really tired. He noticed his blood pressure last visit with Dr. (name withheld) was a little elevated, the Blood pressure is still a little elevated, he hasn't changed anything, he initially states that his Blood pressure is usually 72 over 144 or 71 over 144, caller then corrects himself he would be dead if that was the case and says the blood pressure was usually 144 over 72 or 144 over 71, that's normal for him, after that he went to urgent care and in the last 3 months it been elevated, at urgent care it was 166 over 81 on 24Mar2022. He has no other issues besides the high blood pressure, there was issues and he's always had water retention before even before the shots, the water retention is in the legs, but it has cleared up with the hydrochlorothiazide. On 06JAN2022, he saw Dr. (name withheld) for laboratory work, he had a cough and got a Viral URI with Cough screening it was a lab test for COVID-19 virus, he took the test on 06Jan2022 at urgent care his blood pressure was 144/90 and the Result to the Viral URI with Cough screening came back negative. He would like to know if these are side effects. He knows his mind and body are well enough but after the 3rd shot, he noticed a difference in his body metabolism, he is sluggish, he doesn't have any issues that the doctor is concerned about and needs to think about what he did or what happened prior. The doctor told him he is pretty good, the last physician in Jun2021 said he was aging properly. The changing of the Blood pressure medication from losartan potassium to hydrochlorothiazide was to address the water retention, which it has subsided. Patient clarified that he has tested negative, the first test was negative or the second test. Patient clarified that they were COVID tests at # Urgent Care. He wants to add that he's always masked up with N95 through whole pandemic. Since he has masked up he has never tested positive for covid. He has missed a weeks worth of work, he's home all week.  Follow-up attempts are completed. No further information is expected.