Aches, pains; Very very cold; Uncomfortable; Toes in pain; Not being able to use her hand; Right shoulder is bothered a lot where she can't use it; Stiff neck,tight shoulder; Bad case of arthritis in shoulder and feet; Not feeling good; Hands and fingers have been swollen up; Worn out; Headache; Pain around knees,toes and knees in pain; Chills; 102 fever; This spontaneous case was reported by a consumer and describes the occurrence of PAIN (Aches, pains), FEELING COLD (Very very cold), DISCOMFORT (Uncomfortable), PAIN IN EXTREMITY (Toes in pain) and MOBILITY DECREASED (Not being able to use her hand) in a female patient of an unknown age who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 033F21A and 044A21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     The patient's past medical history included Knee replacement (History of two knee replacements). Concurrent medical conditions included Osteoarthritis. Concomitant products included MELOXICAM for Osteoarthritis.   On 15-Mar-2021, the patient received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 08-Nov-2021, received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On an unknown date, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On an unknown date, the patient experienced PAIN (Aches, pains), FEELING COLD (Very very cold), DISCOMFORT (Uncomfortable), PAIN IN EXTREMITY (Toes in pain), MOBILITY DECREASED (Not being able to use her hand), MUSCULOSKELETAL DISCOMFORT (Right shoulder is bothered a lot where she can't use it), MUSCULOSKELETAL STIFFNESS (Stiff neck,tight shoulder), ARTHRITIS (Bad case of arthritis in shoulder and feet), FEELING ABNORMAL (Not feeling good), PERIPHERAL SWELLING (Hands and fingers have been swollen up), FATIGUE (Worn out), HEADACHE (Headache), ARTHRALGIA (Pain around knees,toes and knees in pain), CHILLS (Chills) and PYREXIA (102 fever). The patient was treated with PARACETAMOL (TYLENOL [PARACETAMOL]) ongoing since an unknown date for Adverse event, at a dose of has been taking extra strength and DOXYCYCLINE for Adverse event, at a dose of for one week. At the time of the report, PAIN (Aches, pains), FEELING COLD (Very very cold), DISCOMFORT (Uncomfortable), PAIN IN EXTREMITY (Toes in pain), MOBILITY DECREASED (Not being able to use her hand), MUSCULOSKELETAL DISCOMFORT (Right shoulder is bothered a lot where she can't use it), MUSCULOSKELETAL STIFFNESS (Stiff neck,tight shoulder), ARTHRITIS (Bad case of arthritis in shoulder and feet), FEELING ABNORMAL (Not feeling good), PERIPHERAL SWELLING (Hands and fingers have been swollen up), FATIGUE (Worn out), HEADACHE (Headache), ARTHRALGIA (Pain around knees,toes and knees in pain), CHILLS (Chills) and PYREXIA (102 fever) outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On 31-Jan-2022, X-ray: not reported (Inconclusive) X-ray done on feet., not reported (Inconclusive) X-ray done on hands and not reported (Inconclusive) X-ray done on shoulders. On an unknown date, COVID-19: negative (Negative) negative. On an unknown date, Influenza: negative (Negative) Negative.         Patient was tested for COVID, flu, strep and all were negative. Last Friday patient went to a rheumatologist and they were going to test her. Patient was trying to find out the cause of what was going on and if there was a long term aches and pain reported.  Company comment: This is a spontaneous case concerning a female patient of unknown age with medical history of osteoarthritis, who experienced the AESI arthritis along with other non-serious events. The events occurred on an unknown day after a booster dose of mRNA-1273 vaccine was administered. Patient went to a rheumatologist and is going to be tested.  X-rays were done on shoulders, hands and feet. Medical history of osteoarthritis remains as a confounder. The benefit -risk relationship of mRNA -1273 vaccine is not affected by this report.   This case was linked to MOD-2021-023532, MOD-2022-468633 (Patient Link).; Sender's Comments: This is a spontaneous case concerning a female patient of unknown age with medical history of osteoarthritis, who experienced the AESI arthritis along with other non-serious events. The events occurred on an unknown day after a booster dose of mRNA-1273 vaccine was administered. Patient went to a rheumatologist and is going to be tested.  X-rays were done on shoulders, hands and feet. Medical history of osteoarthritis remains as a confounder. The benefit -risk relationship of mRNA -1273 vaccine is not affected by this report.