unable to stay standing without falling; getting anxiety ridden; tried to get out of bed and fell; couldn't talk; memory started to go; tremor in right, dominant hand; feeling sick; A spontaneous report was received from a consumer regarding a 69-year-old, female patient who received the Moderna COVID-19 Vaccine (mRNA-1273) and experienced tremors in right, dominant hand/tremor, trouble standing but was not falling down/balance disorder, feeling sick/malaise, tried to get out of bed and fell/fall, memory started to go/memory impairment, couldn't talk/aphasia, and  getting anxiety ridden/anxiety.  The patient's medical history included Lyme Disease, severe back problems, high cholesterol, acid reflux, sleep disturbances and nerve pain.   Concomitant products known to have been used by the patient, within two weeks prior to the event, included Hydroxychloroquine, Clarithromycin, Amoxicillin, Doxycycline, Lipitor 80 mg, Oxycodone 45 mg four times daily, Trazodone, Ambien, Pepcid, Lyrica, Pantoprazole 40 mg, Cyclobenzaprine, Valium 5 mg, Klonopin 0.5 mg.   On 12FEB2021, the patient received the second of two planned doses of mRNA-1273 (BATCH: 013L2DA) intramuscularly in the right arm for prophylaxis of COVID-19 infection.  On 23FEB2021, the patient reported the following events after receiving the first dose of Moderna COVID-19 (mRNA 1273) Vaccine: "The patient reported that on 15Jan2021, she received her first dose of the Moderna COVID-19 Vaccine in her left non-dominant arm, at her local Department of Health. Within days after receiving her first dose, she experienced tremor in her right, dominant hand. The patient reported that her hand was shaking, and she was dropping things, spilling and had trouble standing but was not falling down. The patient reported that prior to receiving her first dose of the Moderna COVID-19 Vaccine, she had been taking Hydroxychloroquine and Clarithromycin to treat Lyme Disease. She had been on these two medications for a couple of weeks. The patient thought that the tremors might have been due to the Hydroxychloroquine and because she was also feeling sick, she stopped taking the Hydroxychloroquine, but continued taking the Clarithromycin. The tremors continued. Her doctor advised her to resume taking the Hydroxychloroquine, starting with ¼ pill, then ½ pill working her way up in dosing. The patient reported that her hand tremors never stopped".  On 23FEB2021, the patient reported the following events after receiving the second dose of Moderna COVID-19 (mRNA 1273) Vaccine:  "On Friday, 12Feb2021, the patient received her second dose of the Moderna COVID-19 Vaccine in her dominant arm, at the same facility. By Monday, 15Feb2021 and Tuesday,16Feb2021, after receiving the second dose, the patient's tremors increased. She reported that she "got much worsening shaking in hand". She was "unable to stay standing without falling". She also stated that her "memory started to go" and she started dropping things such as glasses of juice, spilling things and her memory was getting worse. On Thursday, 18Feb2021, the patient reported it started getting so bad, "tried to get out of bed and fell". She stated that she tried to hold on to something but her body would twist and she wound up on the floor. On Friday, 19Feb2021 her husband called Emergency Medical Services (EMS) and had her taken to the hospital. She stated that she couldn't remember what day it was, who was the President, her date of birth or a lot of things. She stated that she was going blank and could not stand up without assistance. She said that she couldn't talk and it was very scary. She was admitted to the hospital on the following day, Saturday, 20Feb2021. She states that she was "getting anxiety ridden" and her "whole body just shakes". The patient stated that they ran a battery of tests and she was discharged the next day, on Sunday, 21Feb2021, because as she stated "they couldn't find anything". The patient informed the hospital that she had had the 2nd Moderna COVID-19 Vaccine. She was told that her symptoms had nothing to do with the vaccine, but she disagrees".  The action taken for Moderna COVID-19 Vaccine was reported hospitalization.  The outcome of the events was reported as recovering.; Reporter's Comments: Very limited information regarding the events has been provided at this time.  Further information has been requested.