dizzy; Headache; Fatigue; Nausea; blood pressure starts rising, it's very high; digestive problems; She also had effects on her heart; losing weight; weakness in her body; she couldn't walk up and down the hallway; She couldn't even lift her arm; her heart was rushing; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP) from medical information team.  A 16 year-old female patient received bnt162b2 (COMIRNATY), administration date Jun2021 (Batch/Lot number: unknown) at the age of 15 years as dose 2, single for covid-19 immunisation. Relevant medical history included: "thyroid" (unspecified if ongoing), notes: the patient had thyroid issues prior getting the vaccine. Family history included: "breast cancer" (unspecified if ongoing), notes: her mom had breast cancer. Concomitant medication(s) included: LEVOTHYROXINE taken for thyroid disorder (ongoing). Vaccination history included: Bnt162b2 (Dose: 1st), administration date: May2021, for Covid-19 immunization. The following information was reported: DIZZINESS (non-serious) with onset Jun2021, outcome "unknown", described as "dizzy"; HEADACHE (non-serious) with onset Jun2021, outcome "not recovered", described as "Headache"; FATIGUE (non-serious) with onset Jun2021, outcome "unknown", described as "Fatigue"; NAUSEA (non-serious) with onset Jun2021, outcome "not recovered", described as "Nausea"; HYPERTENSION (non-serious) with onset Jun2021, outcome "unknown", described as "blood pressure starts rising, it's very high"; DYSPEPSIA (non-serious) with onset Jun2021, outcome "unknown", described as "digestive problems"; CARDIAC DISORDER (non-serious) with onset Jun2021, outcome "unknown", described as "She also had effects on her heart"; WEIGHT DECREASED (non-serious) with onset Jun2021, outcome "recovering", described as "losing weight"; ASTHENIA (non-serious) with onset Jun2021, outcome "recovering", described as "weakness in her body"; GAIT DISTURBANCE (non-serious) with onset Jun2021, outcome "unknown", described as "she couldn't walk up and down the hallway"; LOSS OF PERSONAL INDEPENDENCE IN DAILY ACTIVITIES (non-serious) with onset Jun2021, outcome "recovering", described as "She couldn't even lift her arm"; PALPITATIONS (non-serious) with onset Jun2021, outcome "recovering", described as "her heart was rushing". The events "dizzy", "headache", "fatigue", "nausea", "blood pressure starts rising, it's very high", "digestive problems", "she also had effects on her heart", "losing weight" were evaluated at the physician office visit and emergency room visit. The events "weakness in her body", "she couldn't walk up and down the hallway", "she couldn't even lift her arm" and "her heart was rushing" were evaluated at the physician office visit. Relevant laboratory tests and procedures are available in the appropriate section. Therapeutic measures were taken as a result of asthenia, gait disturbance, loss of personal independence in daily activities, palpitations. The patient had the 2nd dose of the Pfizer Covid 19 vaccine, the orange one, in Jun2021 and then the patient experienced fatigue, headache, digestive problems and nausea. She also had effects on her heart and she dropped out of school. She had thyroid issues prior to getting the vaccine and was taking levothyroxine. She had received IV's, and was taking salt tablets to increase her sodium levels in her body. She was sent to a Gynecologist and was told that everything was okay. They she went to a Gastroenterologist who did an endoscopy and a colonoscopy and everything was negative. Then she went to a Cardiologist for blood testing, and now she was scheduled to go to a Neurologist on Tuesday. The caller mentioned another patient that was going through the same situation as his grand daughter, the other patient is female, 22 years old. Caller states that the first shot did not bother his grand daughter at all, but the 2nd shot really hit her.  The lot number for bnt162b2 was not provided and will be requested during follow up.