After receiving second dose starting having a flare up of rheumatoid arthritis; More fatigued; pains in the wrist and shoulders.; pains in the wrist and shoulders.; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP) from medical information team for a Pfizer sponsored program (005570). The reporter is the patient. Other Case identifier(s): US-PFIZER INC-202101698166 (Pfizer).  A 81 year-old female patient received bnt162b2 (BNT162B2), administered in arm left, administration date 21Apr2021 (Lot number: ER8733) at the age of 81 years as dose 2, single for covid-19 immunisation. Relevant medical history included: "rheumatoid arthritis" (unspecified if ongoing), notes: she had the rheumatoid arthritis 21 or 22 years ago, "had breast cancer" (unspecified if ongoing), notes: The caller states she received the vaccine in the left arm because the caller had breast cancer and does not do anything in the right arm. After receiving second dose starting having a flare up of rheumatoid arthritis: The caller thought the rheumatoid arthritis flare up would go away sooner than later. The caller was getting ready to receive her third dose Pfizer Covid Vaccine and wanted to think about it. The rheumatoid arthritis flare up was interfering with the activities the caller has been able to do up to now, like cleaning the house. The caller received the second dose Pfizer Covid Vaccine in April or May. Shortly, thereafter within a week or two if that long, the rheumatoid arthritis flare up began. The rheumatoid arthritis flare up comes and goes. The weather does not effect the caller, the colder the better, the caller was different from other people. She has always had some fatigue with rheumatoid arthritis but the fatigue was twice as much as before. The fatigue started two weeks after receiving the second dose Pfizer Covid Vaccine. The caller states it was hard to inspire herself to do thinks when she knows she had to do things because the caller feels so tired. Some days are better than others but the better days are few in between. The caller states she could go to her car and get her vaccine car, it takes effort, but the caller tries to do what she needs to do. The caller states she had to leave her grans behind so she is not exposed. The callers grandkids have not received their vaccines. She did not take flu vaccines or anything, and didn't take any vaccine since was a kid. There was no other vaccinations taken within four weeks prior to the first administration date of the suspect vaccine(s). There were no concomitant medications. Vaccination history included: Bnt162b2 (First dose: 05Apr2021 , lot: EP7533 or FP7533, caller is not sure if the first digit is an E or an F. , NDC: Unknown , Expiration: Unknown , Route of administration: left arm), administration date: 05Apr2021, when the patient was 81 years old, for COVID-19 immunization. The following information was reported: RHEUMATOID ARTHRITIS (non-serious), outcome "unknown", described as "After receiving second dose starting having a flare up of rheumatoid arthritis"; FATIGUE (non-serious), outcome "not recovered", described as "More fatigued"; ARTHRALGIA (non-serious), ARTHRALGIA (non-serious), outcome "unknown" and all described as "pains in the wrist and shoulders.".