platelets caused the blood clots; hair loss; fever; My daily headaches were sharp and intense; tinnitus; blurry vision; light sensitivity/managed light cooking and dishes by sitting in a chair; noise and activity intolerance exercise intolerance/noise and activity caused over stimulation; poor endurance; could not sleep/insomnia; brain fog; inability to focus/concentrate; poor short term memory; head congestion; burning and tingling hands/feet; chest vibrations/tremors inside my chest/felt like a cell phone that I couldn't turn off; adrenaline dumps; weight loss; POTS (Postural orthostatic tachycardia syndrome); burning and tingling hands/feet; muscle weakness; diarrhea; raised my heart rate to 140 simply by standing up; breathless; blood vessel inflammation; fatigue; abnormal platelet activation; This is a spontaneous report received from contactable reporter(s) (Physician and Nurse).  A 62-year-old female patient received BNT162b2 (BNT162B2), as dose 2, single (Batch/Lot number: unknown) for covid-19 immunisation. The patient's relevant medical history and concomitant medications were not reported. Vaccination history included: Covid-19 vaccine (Dose: 1, Unknown manufacturer.), for COVID-19 Immunization. The following information was reported: THROMBOSIS (medically significant), outcome "unknown", described as "platelets caused the blood clots"; ALOPECIA (non-serious), outcome "unknown", described as "hair loss"; PYREXIA (non-serious), outcome "unknown", described as "fever"; HEADACHE (non-serious), outcome "not recovered", described as "My daily headaches were sharp and intense"; TINNITUS (non-serious), outcome "unknown"; VISION BLURRED (non-serious), outcome "unknown", described as "blurry vision"; PHOTOPHOBIA (non-serious), outcome "unknown", described as "light sensitivity/managed light cooking and dishes by sitting in a chair"; HYPERACUSIS (non-serious), outcome "unknown", described as "noise and activity intolerance exercise intolerance/noise and activity caused over stimulation"; EXERCISE TOLERANCE DECREASED (non-serious), outcome "unknown", described as "poor endurance"; INSOMNIA (non-serious), outcome "unknown", described as "could not sleep/insomnia"; FEELING ABNORMAL (non-serious), outcome "unknown", described as "brain fog"; DISTURBANCE IN ATTENTION (non-serious), outcome "unknown", described as "inability to focus/concentrate"; MEMORY IMPAIRMENT (non-serious), outcome "unknown", described as "poor short term memory"; UPPER RESPIRATORY TRACT CONGESTION (non-serious), outcome "unknown", described as "head congestion"; PARAESTHESIA (non-serious), BURNING SENSATION (non-serious), outcome "unknown" and all described as "burning and tingling hands/feet"; CHEST DISCOMFORT (non-serious), outcome "unknown", described as "chest vibrations/tremors inside my chest/felt like a cell phone that I couldn't turn off"; ADRENAL DISORDER (non-serious), outcome "unknown", described as "adrenaline dumps"; WEIGHT DECREASED (non-serious), outcome "unknown", described as "weight loss"; POSTURAL ORTHOSTATIC TACHYCARDIA SYNDROME (non-serious), outcome "unknown", described as "POTS (Postural orthostatic tachycardia syndrome)"; MUSCULAR WEAKNESS (non-serious), outcome "unknown", described as "muscle weakness"; DIARRHOEA (non-serious), outcome "unknown", described as "diarrhea"; HEART RATE INCREASED (non-serious), outcome "unknown", described as "raised my heart rate to 140 simply by standing up"; DYSPNOEA (non-serious), outcome "unknown", described as "breathless"; VASCULITIS (non-serious), outcome "unknown", described as "blood vessel inflammation"; FATIGUE (non-serious), outcome "unknown"; PLATELET DISORDER (non-serious), outcome "unknown", described as "abnormal platelet activation". The events "platelets caused the blood clots", "hair loss", "fever", "my daily headaches were sharp and intense", "tinnitus", "blurry vision", "light sensitivity/managed light cooking and dishes by sitting in a chair", "noise and activity intolerance exercise intolerance/noise and activity caused over stimulation", "poor endurance", "could not sleep/insomnia", "brain fog", "inability to focus/concentrate", "poor short term memory", "head congestion", "burning and tingling hands/feet", "chest vibrations/tremors inside my chest/felt like a cell phone that i couldn't turn off", "adrenaline dumps", "weight loss", "pots (postural orthostatic tachycardia syndrome)", "muscle weakness", "diarrhea", "raised my heart rate to 140 simply by standing up", "breathless", "blood vessel inflammation", "fatigue" and "abnormal platelet activation" required physician office visit. The patient underwent the following laboratory tests and procedures: Blood test: blood vessel inflammation and abnormal platelet, notes: activation; Heart rate: 140, notes: symptoms raised my heart rate to 140; Weight: Loss. Therapeutic measures were taken as a result of headache. The information on the batch/lot number for BNT162b2 has been requested and will be submitted if and when received.  Follow up (06Apr2022): This is a follow-up spontaneous report received from non-contactable physician and Nurse (patient). Updated information included: New reporter in slider#2 and slider#3 updated, Patient name, gender, age reported, historical vaccine, all lab data, suspect information included dose number reported and events added. case updated as serious.; Sender's Comments: Based on the current available limited information in the case provided, the causal association between the events and the use of suspect product BNT162B2 cannot be fully excluded.  The impact of this report on the benefit/risk profile of the Pfizer product is evaluated as part of Pfizer procedures for safety evaluation, including the review and analysis of aggregate data for adverse events. Any safety concern identified as part of this review, as well as any appropriate action in response, will be promptly notified to regulatory authorities, Ethics Committees, and Investigators, as appropriate.