she started having nerve pain in the same arm that would go all the way down her arm; Uncomfortable; she was scratching her back because it itched; had red welts down along her vertebrae below her waist and above her tailbone; discovered two pox on her back /  There were also two places that looked like pox had fallen off/ After seeing the pox she realized she had shingles; started having severe pain in her back; She experiencing fever; She experiencing  shivering; She experiencing nausea; She also had pain, redness and swelling in her arm where she got the injection; She also had pain, redness and swelling in her arm where she got the injection; She also had pain, redness and swelling in her arm where she got the injection; This case was reported by a consumer via call center representative and described the occurrence of fever in a 60-year-old female patient who received Herpes zoster (Shingrix) for prophylaxis.   The patient's past medical history included shingles (twice).   On 16th January 2020, the patient received the 1st dose of Shingrix (intramuscular). On 15th March 2020, 59 days after receiving Shingrix, the patient experienced back pain and shingles. On 23rd March 2020, the patient experienced pruritus and erythema urticarial. On an unknown date, the patient experienced fever, shivering, nausea, injection site pain, injection site erythema, injection site swelling, nerve pain and discomfort. On an unknown date, the outcome of the fever, shivering, nausea, injection site pain, injection site erythema, injection site swelling and nerve pain were recovered/resolved and the outcome of the discomfort, pruritus and shingles were unknown and the outcome of the back pain was recovering/resolving and the outcome of the erythema urticarial was not recovered/not resolved.   It was unknown if the reporter considered the fever, shivering, nausea, injection site pain, injection site erythema, injection site swelling, nerve pain, discomfort, back pain, pruritus, erythema urticarial and shingles to be related to Shingrix.  Additional details were reported as follows: The patient received the Shingrix on an unknown arm and experienced fever, shivering and nausea for about 2-3 days after getting the vaccine. She also had pain, redness and swelling in her arm where she got the injection that lasted 1.5-2 weeks. After those symptoms resolved she started having nerve pain in the same arm that would go all the way down her arm. This nerve pain would come and go and was very uncomfortable. The nerve pain finally resolved about 1 month ago. On 15th March 2020 she started having severe pain in her back. At first she thought she had injured her back, but on 23rd March 2020 she was scratching her back because it itched and discovered two pox on her back. There were also two places that looked like pox had fallen off. She also had red welts down along her vertebrae below her waist and above her tailbone, where she was experiencing the pain. After seeing the pox she realized she had shingles, so she called her doctor and a prescription was called in for acyclovir. The welts never broke out in full blisters, but are still present. The pain has mostly resolved. She has had two previous cases of shingles, prior to getting Shingrix, and those occurred higher up on her right side from where the welts are. The previous cases of shingles were more in the location of the pox. The current welts are lower down and more central. Consented to follow up.