my throat became tight/Sensation of throat closing; trouble breathing/hard time breathing; blood pressure was elevated; Swelling of upper airway (lips, tongue, throat, uvula, or larynx); Systolic blood pressure <90 mmHg; Diarrhea; Difficulty swallowing; Chest tightness; Cough/ dry cough; Numbness; Feeling hot; Local itching; have a hard time walking; missed work; Rash generalised; extreme joint pain; Nausea; temp of 100; This spontaneous case was reported by a consumer and describes the occurrence of THROAT TIGHTNESS (my throat became tight/Sensation of throat closing), DYSPNOEA (trouble breathing/hard time breathing), BLOOD PRESSURE INCREASED (blood pressure was elevated), OROPHARYNGEAL DISCOMFORT (Swelling of upper airway (lips, tongue, throat, uvula, or larynx)) and BLOOD PRESSURE SYSTOLIC DECREASED (Systolic blood pressure <90 mmHg) in a 56-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 050C21A and 034C21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     Previously administered products included for an unreported indication: FLU VACCINE VII in 2007. Concurrent medical conditions included Penicillin allergy (Hives, trouble breathing), Allergy to antibiotic (Allergy to Tetracycline,  Hives, trouble breathing), Drug allergy (Allergy to Percocet, Unable to breathe.) since 27-Aug-1999 and Allergy to antibiotic (Allergy to Septra.Hives, trouble breathing).   On 03-Sep-2021 at 3:00 PM, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 01-Oct-2021 at 3:15 PM, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On an unknown date, the patient experienced THROAT TIGHTNESS (my throat became tight/Sensation of throat closing), DYSPNOEA (trouble breathing/hard time breathing), BLOOD PRESSURE INCREASED (blood pressure was elevated), OROPHARYNGEAL DISCOMFORT (Swelling of upper airway (lips, tongue, throat, uvula, or larynx)), BLOOD PRESSURE SYSTOLIC DECREASED (Systolic blood pressure <90 mmHg), DIARRHOEA (Diarrhea), DYSPHAGIA (Difficulty swallowing), CHEST DISCOMFORT (Chest tightness), COUGH (Cough/ dry cough), HYPOAESTHESIA (Numbness), FEELING HOT (Feeling hot), PRURITUS (Local itching), GAIT DISTURBANCE (have a hard time walking), IMPAIRED WORK ABILITY (missed work), RASH (Rash generalised), ARTHRALGIA (extreme joint pain), NAUSEA (Nausea) and PYREXIA (temp of 100). The patient was treated with DIPHENHYDRAMINE HYDROCHLORIDE (BENADRYL [DIPHENHYDRAMINE HYDROCHLORIDE]) from 03-Sep-2021 to 06-Oct-2021 for Adverse event, at a dose of 25 milligram, every 4 hrs. At the time of the report, THROAT TIGHTNESS (my throat became tight/Sensation of throat closing), DYSPNOEA (trouble breathing/hard time breathing), BLOOD PRESSURE INCREASED (blood pressure was elevated), OROPHARYNGEAL DISCOMFORT (Swelling of upper airway (lips, tongue, throat, uvula, or larynx)), BLOOD PRESSURE SYSTOLIC DECREASED (Systolic blood pressure <90 mmHg), DIARRHOEA (Diarrhea), DYSPHAGIA (Difficulty swallowing), CHEST DISCOMFORT (Chest tightness), COUGH (Cough/ dry cough), HYPOAESTHESIA (Numbness), FEELING HOT (Feeling hot), PRURITUS (Local itching), GAIT DISTURBANCE (have a hard time walking), IMPAIRED WORK ABILITY (missed work), RASH (Rash generalised), ARTHRALGIA (extreme joint pain), NAUSEA (Nausea) and PYREXIA (temp of 100) had not resolved. Not Provided    DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On an unknown date, Body temperature: 100 (High) high.         Patient experienced Tight throat, unable to breathe in 2007 after the flu shot. No concomitant medications were reported. Patient was treated with Oxygen on 03-Sep-2021.   This case was linked to MOD-2021-315846 (Patient Link).