Nasal Swab: Positive; Nasal Swab: Positive; enlarged Virchow's lymph node; developed cystic acne on my left cheek; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP). The reporter is the patient.  A 40 year-old female patient (not pregnant) received bnt162b2 (BNT162B2), administered in arm left, administration date 29Dec2021 13:00 (Batch/Lot number: unknown) at the age of 39 years as dose 3 (booster), single for covid-19 immunisation. Relevant medical history included: "Known allergies: Seasonal allergies" (unspecified if ongoing). Concomitant medication(s) included: FEXOFENADINE. Vaccination history included: Bnt162b2 (prev dose product=COVID 19,, prev dose brand=Pfizer,, prev dose brand unknown=False,, prev dose lot unknown=True,, prev dose lot unknown reason=Unable to locate or read the details,, prev dose administration date=13May2021, prev dose dose number=2,, prev dose vaccine location=Left arm), administration date: 13May2021, when the patient was 39 years old, for COVID-19 immunization; Bnt162b2 (prev dose product=COVID 19,, prev dose brand=Pfizer,, prev dose brand unknown=False,, prev dose lot unknown=True,, prev dose lot unknown reason=Unable to locate or read the details,, prev dose administration date=19Apr2021, prev dose dose number=1,, prev dose vaccine location=Left arm), administration date: 19Apr2021, when the patient was 39 years old, for COVID-19 immunization. The following information was reported: COVID-19 (medically significant), VACCINATION FAILURE (medically significant) all with onset 03Feb2022, outcome "unknown" and all described as "Nasal Swab: Positive"; LYMPHADENOPATHY (non-serious) with onset 31Dec2021, outcome "not recovered", described as "enlarged Virchow's lymph node"; ACNE CYSTIC (non-serious) with onset 31Dec2021, outcome "not recovered", described as "developed cystic acne on my left cheek". The events "enlarged virchow's lymph node" and "developed cystic acne on my left cheek" were evaluated at the physician office visit. No other vaccine in four weeks. Other medications in two weeks was fexofenadine It was reported that patient had first event 2 days after 3rd vaccine she found a supraclavicular, hard pea sized lump. Doctor diagnosed it as an enlarged Virchow's lymph node. It was still present 3 months after the 3rd vaccine. She had several blood tests, ultrasounds & x-rays but all came back healthy and not indicating any other health problems. Second event 2-3 weeks after 3rd dose of vaccine, she developed cystic acne on my left cheek. She never had this before in her life. It got persistently worse, and after 2 months had now spread to her right cheek, chin, and jaw area. No covid prior vaccination. She had tested covid post vaccination. The patient underwent the following laboratory tests and procedures: blood test: (unspecified date) came back healthy, notes: I had several blood tests, ultrasounds & x-rays but all came back healthy and not indicating any other health problems; sars-cov-2 test: (03Feb2022) positive; ultrasound scan: (unspecified date) came back healthy, notes: I had several blood tests, ultrasounds & x-rays but all came back healthy and not indicating any other health problems; x-ray: (unspecified date) came back healthy, notes: I had several blood tests, ultrasounds & x-rays but all came back healthy and not indicating any other health problems. Therapeutic measures were not taken as a result of lymphadenopathy, acne cystic.  The lot number for bnt162b2 was not provided and will be requested during follow up.