Headache/had headaches that continued into Saturday/started getting bad headaches on Sunday; Sore throat/started getting sore throat; broke out in very large aphthous ulcers on back of her throat and palate which are still there; Broke out and is recovering from giant ulcers on the back of the throat/broke out in very large aphthous ulcers on back of her throat and palate.; Chills; Exhaustions; Body aches/still has body aches but stated it is much better.; This spontaneous case was reported by an other health care professional and describes the occurrence of PHARYNGEAL ULCERATION (Broke out and is recovering from giant ulcers on the back of the throat/broke out in very large aphthous ulcers on back of her throat and palate.), OROPHARYNGEAL PAIN (Sore throat/started getting sore throat), PALATAL ULCER (broke out in very large aphthous ulcers on back of her throat and palate which are still there), HEADACHE (Headache/had headaches that continued into Saturday/started getting bad headaches on sunday) and CHILLS (Chills) in a 55-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 005M21A, 017E21A, 031LR0A and 042L20A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     Patient had no any past medical history of allergies.    On 20-Jan-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 19-Feb-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. On 19-Aug-2021, received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. On 08-Apr-2022, received fourth dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. On 08-Apr-2022, the patient experienced OROPHARYNGEAL PAIN (Sore throat/started getting sore throat) and HEADACHE (Headache/had headaches that continued into Saturday/started getting bad headaches on sunday). In April 2022, the patient experienced PHARYNGEAL ULCERATION (Broke out and is recovering from giant ulcers on the back of the throat/broke out in very large aphthous ulcers on back of her throat and palate.), PALATAL ULCER (broke out in very large aphthous ulcers on back of her throat and palate which are still there), CHILLS (Chills), FATIGUE (Exhaustions) and MYALGIA (Body aches/still has body aches but stated it is much better.). At the time of the report, PHARYNGEAL ULCERATION (Broke out and is recovering from giant ulcers on the back of the throat/broke out in very large aphthous ulcers on back of her throat and palate.), OROPHARYNGEAL PAIN (Sore throat/started getting sore throat), PALATAL ULCER (broke out in very large aphthous ulcers on back of her throat and palate which are still there) and HEADACHE (Headache/had headaches that continued into Saturday/started getting bad headaches on sunday) had not resolved, CHILLS (Chills) and FATIGUE (Exhaustions) outcome was unknown and MYALGIA (Body aches/still has body aches but stated it is much better.) was resolving.        For mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular), the reporter did not provide any causality assessments.   No concomitant medications were reported.  It was reported that after the second booster dose patient had no fever but had headaches that continued into Saturday (09 Apr 2022) with exhaustions. Patient then started getting bad headaches and sore throat again on Sunday, 10 Apr 2022, with additional symptoms after 48 hours.  No treatment medications were reported.   This case was linked to MOD-2022-538666, MOD-2022-538659, MOD-2022-538668 (Patient Link).