swelling to her right leg; debilitating fatigue; severe h/a; severe productive cough; DOE; palpitations; chest pain midsubsternal non-radiating pain, sharp type 8/10 on pain scale; reoccurring swelling of injected arm even after a month of getting last vaccine; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP). The reporter is the patient.  A 39-year-old female patient (not pregnant) received bnt162b2 (BNT162B2), administration date 23Jan2022 (Lot number: FL3198) at the age of 39 years as dose 2, single for covid-19 immunisation; measles vaccine, mumps vaccine, rubella vaccine (MMR), administered in deltoid left, administration date 21Jan2022 (Lot number: 034392) as unk, single. Relevant medical history included: "Known Allergy: Latex" (unspecified if ongoing); "Endometriosis" (unspecified if ongoing); "asthma" (unspecified if ongoing); "Known allergies: dairy" (unspecified if ongoing); "Known allergies: adhesive tape" (unspecified if ongoing). The patient took concomitant medications (unspecified medications). Past drug history included: Codeine, reaction(s): "Drug allergy: codiene"; Imatrex, reaction(s): "Drug allergy". Vaccination history included: Bnt162b2 (Dose 1, Lot: GL3198, administration time: 02:30 PM, Dose vaccine location: Left arm), administration date: 02Jan2022, when the patient was 39 years old, for COVID-19 Immunization, reaction(s): "pain in left armpit", "lymphedema". The following information was reported: FATIGUE (disability) with onset 23Jan2022, outcome "unknown", described as "debilitating fatigue"; HEADACHE (non-serious) with onset 23Jan2022, outcome "unknown", described as "severe h/a"; PRODUCTIVE COUGH (non-serious) with onset 23Jan2022, outcome "unknown", described as "severe productive cough"; DYSPNOEA EXERTIONAL (non-serious) with onset 23Jan2022, outcome "unknown", described as "DOE"; PALPITATIONS (non-serious) with onset 23Jan2022, outcome "unknown", described as "palpitations"; CHEST PAIN (non-serious) with onset 23Jan2022, outcome "unknown", described as "chest pain midsubsternal non-radiating pain, sharp type 8/10 on pain scale"; VACCINATION SITE SWELLING (non-serious) with onset 23Jan2022, outcome "unknown", described as "reoccurring swelling of injected arm even after a month of getting last vaccine"; PERIPHERAL SWELLING (non-serious) with onset Mar2022, outcome "unknown", described as "swelling to her right leg". Clinical course was reported as follows. Four hours after vaccine c/o sudden onset of severe productive cough, severe h/a, DOE, palpitations, chest pain midsubsternal nonradiating pain  sharp type 8/10 on pain scale lasted about 4 hours  went to hospital, acute ACS and pneumonia were r/o. She was d/c to home and told to f/u with PCP and specialist. Debilitating fatigue, severe headaches that have last for 3-4 hours reoccurring swelling of injected arm even after a month of getting last vaccine. In Mar2022, she had swelling to her right leg.; Sender's Comments: Based on the available reported information, the causal association between the event fatigue and the suspect drug BNT162B2 cannot be excluded. The impact of this report on the benefit/risk profile of the Pfizer product is evaluated as part of Pfizer procedures for safety evaluation, including the review and analysis of aggregate data for adverse events. Any safety concern identified as part of this review, as well as any appropriate action in response, will be promptly notified to regulatory authorities, Ethics Committees, and Investigators, as appropriate.