Blood pressure has been higher; Predominantly chest pain for which cardiac issues have been eliminated; This is a spontaneous report from a contactable consumer (patient herself). A 43-years-old female patient received first dose of BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE, Formulation: Solution for injection, lot number and expiration date was not reported) via an unspecified route of administration, administered in Arm Left on 31Mar2021 15:30 (at the age of 43-years-old) as DOSE 1, SINGLE for COVID-19 immunization. Medical history included ongoing rheumatoid arthritis; diagnosed probably 10 years ago, costochondritis; caller stated they diagnosed her with costochondritis, and she has had it before, myocardial infraction and neoplasm malignant from an unknown date and unknown if ongoing. Family medical history relevant to AE(s): Grandfather died young from heart attack. States her mom was never healthy, but she did not know if that was related and she did not have any problems with Pfizer vaccine. Caller stated they have the typically cancer and stuff. Concomitant medication included adalimumab (HUMIRA) taken for rheumatoid arthritis from 2017 and ongoing. Humira: supposed to do every other week but she does it every month and okayed with rheumatologist. Past 6 Years; Past 4 years been spacing it out. Summer she did 5 weeks, winter 4 weeks. Tried to go off. Patient did not receive any other vaccines within 4 weeks prior to the COVID vaccine. AE(s) following prior vaccination was reported as none. Patient received the 1st dose of the Pfizer COVID vaccine on 31Mar2021, but has complained of side effects since, predominantly chest pain on 01Apr2021for which cardiac issues have been eliminated. Caller was being followed by a Rheumatologist and was being treated for the symptoms. Caller wanted to know. Caller enquired if she just get the one shot and not the other, what would the efficacy of one dose. The chest pain was not as bad, but it has been 7 weeks and she had not gotten her second shot because she has not been up to it. Caller was asking for additional information about her chest pain and if it was normal to still have it 7 weeks later and guidelines on the second vaccine. Caller stated the chest pain was pretty awful and probably the worst she had ever felt. Stated she could especially feel it when she would cough, sneeze or breathe. Caller Stated she was not sure if it was from the vaccine or her autoimmune disorder on overdrive with having the vaccine in her body because it was not something it is used to. Caller states sometimes her blood pressure has been higher, but she thought it was because she was stressed out. Caller Stated she went to an urgent care on 04Apr2021 and it her blood pressure was elevated and she went back again and they did not say anything, so she assumed it was better. Caller stated her heart looked fine. AEs resulted in emergency room and physician office visit. Emergency Room/Urgent Care 04Apr2021 and back for a follow up that Friday 10Apr2021. Treatment- gave muscle relaxers, prednisone dose pack, lots of Advil. Prednisone came after her rheumatologist appointment on 21Apr2021. Caller states her blood work showed COVID antibodies. Caller asked whether that means she had COVID or not or whether they were from the vaccine?. Caller stated she was a vegan, healthy, and she was in good shape. Caller states she took Humira the week before the shot. The patient underwent lab tests and procedures which included blood test, electrocardiogram and chest x-ray which was normal, SARS-COV-2 antibody test: positive on an unspecified date. This report was not serious. The outcome of event predominantly chest pain for which cardiac issues have been eliminated was resolving while outcome of blood pressure has been higher was resolved on an unspecified date in Apr2021.  No follow-up attempts are needed; information about lot/batch number cannot be obtained.