He had mast cell activation as well; He has side effect from the vaccine; He had a very bad hyperadrenergic syndrome; My son is having emotional difficulties; He is very sick; This spontaneous case was reported by a consumer and describes the occurrence of MAST CELL ACTIVATION SYNDROME (He had mast cell activation as well) in a male patient of an unknown age who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. Unknown) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     Concurrent medical conditions included Mast cell activation syndrome.    On an unknown date, the patient received dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On an unknown date, the patient experienced MAST CELL ACTIVATION SYNDROME (He had mast cell activation as well) (seriousness criterion medically significant), VACCINATION COMPLICATION (He has side effect from the vaccine), POSTURAL ORTHOSTATIC TACHYCARDIA SYNDROME (He had a very bad hyperadrenergic syndrome), EMOTIONAL DISTRESS (My son is having emotional difficulties) and ILLNESS (He is very sick). At the time of the report, MAST CELL ACTIVATION SYNDROME (He had mast cell activation as well), VACCINATION COMPLICATION (He has side effect from the vaccine), POSTURAL ORTHOSTATIC TACHYCARDIA SYNDROME (He had a very bad hyperadrenergic syndrome), EMOTIONAL DISTRESS (My son is having emotional difficulties) and ILLNESS (He is very sick) outcome was unknown.        The action taken with mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) was unknown.       No Concomitant medications were reported. No treatment medications were reported. Caller was looking for information about the excipients of the Moderna COVID-19 vaccine because she and her son suffer from primary mast cell activation (hereditary condition) and have horrible side effects to . She had not received the vaccine because of her condition but that her son received the vaccine without asking her and he developed side effects from it, he was new to the condition and had a very bad hyperadrenergic syndrome ) and mast cell activation as well. Caller did not give consent for follow up with Safety team, she stated her son was having emotional difficulties and was very sick. Company comment: This is a spontaneous case concerning a male patient of an unknown age with medical history of primary mast cell activation (hereditary condition) and have horrible side effects to , who experienced the serious, unexpected, event of Mast cell activation syndrome and other non-serious events such as Postural orthostatic tachycardia syndrome ) among others. The events occurred on an unknown date. The patient received a dose of mRNA-1273 vaccine on an unknown date. The mentioned medical history remains a confounder. The benefit-risk relationship of mRNA-1273 vaccine is not affected by this report.; Sender's Comments: This is a spontaneous case concerning a male patient of an unknown age with medical history of primary mast cell activation (hereditary condition) and have horrible side effects to PEG, who experienced the serious, unexpected, event of Mast cell activation syndrome and other non-serious events such as Postural orthostatic tachycardia syndrome ) among others. The events occurred on an unknown date. The patient received a dose of mRNA-1273 vaccine on an unknown date. The mentioned medical history remains a confounder. The benefit-risk relationship of mRNA-1273 vaccine is not affected by this report.