This is a spontaneous report received from a contactable reporter (Consumer or other non HCP). The reporter is the patient. A 43 year-old male patient received bnt162b2 (Pfizer-BioNTech COVID-19), administered in arm right, administration date 19Feb2021 (Lot number: EN5318) at the age of 43 years as dose 2, single for Covid-19 immunisation. The patient had no relevant medical history. There were no concomitant medications in 2 weeks. Vaccination history included: Bnt162b2 (Previous dose lot number: EL3248, Previous dose administration date: 29Jan2021 , Previous dose dose number: 1, Previous dose vaccine location: Right arm), administration date: 29Jan2021, when the patient was 43 years old, for Covid 19 immunization. Patient had no known allergies. The patient had not received any other vaccine within 4 weeks. The following information was reported: DYSPNOEA (hospitalization, disability, life threatening) with onset 22Feb2021 12:00, outcome "not recovered", described as "Shortness of breath"; CHEST DISCOMFORT (hospitalization, disability, life threatening) with onset 22Feb2021 12:00, outcome "not recovered", described as "tightness in chest"; NERVOUS SYSTEM DISORDER (hospitalization, disability, life threatening) with onset 22Feb2021 12:00, outcome "not recovered", described as "neurological issues"; HYPOAESTHESIA (hospitalization, disability, life threatening), PARAESTHESIA (hospitalization, disability, life threatening) all with onset 22Feb2021 12:00, outcome "not recovered" and all described as "numbness and tingling in extremities and limbs"; MUSCULAR WEAKNESS (hospitalization, disability, life threatening) with onset 22Feb2021 12:00, outcome "not recovered", described as "weakness in limps and extremities"; DIPLOPIA (hospitalization, disability, life threatening), VISION BLURRED (hospitalization, disability, life threatening) all with onset 22Feb2021 12:00, outcome "not recovered" and all described as "double and blurred vision"; HEART RATE IRREGULAR (hospitalization, disability, life threatening), BLOOD PRESSURE ABNORMAL (hospitalization, disability, life threatening) all with onset 22Feb2021 12:00, outcome "not recovered" and all described as "irregular heart rate and blood pressure"; THINKING ABNORMAL (hospitalization, disability, life threatening) with onset 22Feb2021 12:00, outcome "not recovered", described as "impaired thought processes"; ANXIETY (hospitalization, disability, life threatening) with onset 22Feb2021 12:00, outcome "not recovered", described as "Anxiety"; DEPRESSION (hospitalization, disability, life threatening) with onset 22Feb2021 12:00, outcome "not recovered", described as "depression". The patient was hospitalized for dyspnoea, chest discomfort, nervous system disorder, hypoaesthesia, paraesthesia, muscular weakness, diplopia, vision blurred, heart rate irregular, blood pressure abnormal, thinking abnormal, anxiety, depression (hospitalization duration: 2 day(s)). The events "shortness of breath", "tightness in chest", "neurological issues", "numbness and tingling in extremities and limbs", "numbness and tingling in extremities and limbs", "weakness in limps and extremities", "double and blurred vision", "double and blurred vision", "irregular heart rate and blood pressure", "irregular heart rate and blood pressure", "anxiety" and "depression" were evaluated at the physician office visit and emergency room visit. The patient underwent the following laboratory tests and procedures: blood pressure measurement: (unspecified date) irregular blood pressure; heart rate: (unspecified date) irregular heart rate; sars-cov-2 test: (08Feb2022) negative, notes: Nasal Swab. Therapeutic measures were taken as a result of dyspnoea, chest discomfort, nervous system disorder, hypoaesthesia, paraesthesia, muscular weakness, diplopia, vision blurred, heart rate irregular, blood pressure abnormal, thinking abnormal, anxiety, depression. Treatment with Stress Test and Echocardiogram. No follow-up attempts are possible. No further information is expected.