heart attack like symptoms; This spontaneous case was reported by a consumer and describes the occurrence of CARDIOVASCULAR SYMPTOM (heart attack like symptoms) in a male patient of an unknown age who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 044AZ1A) for COVID-19 vaccination.     The patient's past medical history included COVID-19 in July 2020, Chemotherapy (chemo/radiation therapies in 2016 for squamous cell throat cancer) in 2016 and Radiation therapy (chemo/radiation therapies in 2016 for squamous cell throat cancer.) in 2016. Concurrent medical conditions included Squamous cell carcinoma of pharynx (immunocompromised as a result of chemo/radiation therapies in 2016 for squamous cell throat cancer).    On 10-Mar-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. In March 2021, the patient experienced CARDIOVASCULAR SYMPTOM (heart attack like symptoms) (seriousness criterion hospitalization). The patient was hospitalized on sometime in March 2021 due to CARDIOVASCULAR SYMPTOM. At the time of the report, CARDIOVASCULAR SYMPTOM (heart attack like symptoms) outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): In 2021, Echocardiogram: 25 percent (abnormal) Heart ejection fraction(HEF) was only 25 percent.     The action taken with mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown) was unknown.       The patient reported that he was transported to medical facility within the week of first dose administration with heart attack like symptoms.The concomitant history was not reported. The treatment history was not provided.  Company Comment: This spontaneous case concerns a male patient of unspecified age with relevant history of previous treatment with Chemotherapy and Radiotherapy for Squamous cell throat cancer, who was hospitalized for experiencing the unexpected event of unspecified Cardiovascular symptom. The event occurred approximately a week after receiving his first dose of mRNA-1273 vaccine. The patient reportedly complained of heart attack-like symptoms and was immediately brought to a hospital. Echocardiogram was conducted which showed low ejection fraction of 25%. He was placed in the Palliative care unit for an unspecified duration afterwards. Further diagnostics and treatment details were not reported in the case. At the time of reporting, the outcome of event was unknown. Previous treatment with chemotherapy and radiotherapy remain as confounders. The benefit-risk relationship of mRNA-1273 is not affected by this report.   This case was linked to MOD-2022-493706 (Patient Link).; Sender's Comments: This spontaneous case concerns a male patient of unspecified age with relevant history of previous treatment with Chemotherapy and Radiotherapy for Squamous cell throat cancer, who was hospitalized for experiencing the unexpected event of unspecified Cardiovascular symptom. The event occurred approximately a week after receiving his first dose of mRNA-1273 vaccine. The patient reportedly complained of heart attack-like symptoms and was immediately brought to a hospital. Echocardiogram was conducted which showed low ejection fraction of 25%. He was placed in the Palliative care unit for an unspecified duration afterwards. Further diagnostics and treatment details were not reported in the case. At the time of reporting, the outcome of event was unknown. Previous treatment with chemotherapy and radiotherapy remain as confounders. The benefit-risk relationship of mRNA-1273 is not affected by this report.