acute tubular necrosis; Minimal change disease; This literature-non-study case was reported in a literature article and describes the occurrence of RENAL TUBULAR NECROSIS (acute tubular necrosis) and GLOMERULONEPHRITIS MINIMAL LESION (Minimal change disease) in an 83-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination.       No Medical History information was reported.    On an unknown date, the patient received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On an unknown date, the patient experienced RENAL TUBULAR NECROSIS (acute tubular necrosis) (seriousness criterion medically significant) and GLOMERULONEPHRITIS MINIMAL LESION (Minimal change disease) (seriousness criterion medically significant). At the time of the report, RENAL TUBULAR NECROSIS (acute tubular necrosis) and GLOMERULONEPHRITIS MINIMAL LESION (Minimal change disease) was resolving.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On an unknown date, Blood albumin: 2.0 g/dl Laboratories during presentation was 2.0 g/dl and 2.7 g/dl Laboratories during last follow up was 2.7 g/dl. On an unknown date, Blood creatinine: 1.19 mg/dl Baseline was 1.19 mg/dl, 2.19 g/dl Laboratories during presentation was 2.19 g/dl and 1.2 g/dl Laboratories during last follow up was 1.2 mg/dl. On an unknown date, Protein urine: 18 g/d Laboratories during presentation was 18 g/d and 2 g/d Laboratories during last follow up was 2 g/d. On an unknown date, Red blood cells urine: less than (<) high power field (hpf) Laboratories during presentation was less than (<) HPF and less than (<) high power field (hpf) Laboratories during presentation was less than (<) 3 /HPF.     For mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown), the reporter considered RENAL TUBULAR NECROSIS (acute tubular necrosis) and GLOMERULONEPHRITIS MINIMAL LESION (Minimal change disease) to be possibly related.    This article reports a case series of patients who developed new or relapsing GN post vaccination.   This patient was newly diagnosed with GN post Moderna COVID-19 vaccination. Patient presented with symptom of Acute kidney injury(AKI). Patient was treated with high dose steroids  Concomitant medications were not reported  This is a literature non study case concerning a 83-year-old, male patient with unknown medical history, who experienced the unexpected serious (medically significant) events of Acute tubular necrosis and Minimal change disease. The events occurred approximately 4 weeks after the second dose of Spikevax with unknown information regarding the first dose. Patient received high dose of steroids and was reported to have respond to treatment on follow up. The rechallenge is not applicable. The benefit-risk relationship of Spikevax is not affected by this report.   This case was linked to MOD-2021-357261, MOD-2021-357609, MOD-2021-357611, MOD-2021-357612, MOD-2021-357613, MOD-2021-357614 (Patient Link).   Most recent FOLLOW-UP information incorporated above includes: On 20-Oct-2021: Follow up received by safety 21-Oct-2021 included an Email and does not contain any new information; Sender's Comments: This is a literature non study case concerning a 83-year-old, male patient with unknown medical history, who experienced the unexpected serious (medically significant) events of Acute tubular necrosis and Minimal change disease. The events occurred approximately 4 weeks after the second dose of Spikevax with unknown information regarding the first dose. Patient received high dose of steroids and was reported to have respond to treatment on follow up. The rechallenge is not applicable. The benefit-risk relationship of Spikevax is not affected by this report.