his legs were extremely weak; has to hold onto something to go through the house; rash is across his upper back, chest, and down both arms; Patient had a dry cough; running a fever; the next morning and it was even worse; flu-like symptoms after both doses; Sore all Over/Achy all over; This is a spontaneous report based on information received by Pfizer from Biontech [manufacturer control number: 40968], license party for Comirnaty. A contactable consumer reported that a 74-year-old male patient received second dose BNT162b2(COMIRNATY, Formulation: Solution for injection, Lot number: EN6207, Expiration: 31Jul2021), via an unspecified route of administration in arm left on 19Mar2021 at single dose for COVID-19 immunization. The patient medical history includes Arthritis (arthritis is in his right foot only and his big toe, diagnosed in 2017 or 2018) and Concomitant medication were not reported. Historical vaccine included BNT162b2 (COMIRNATY) on 26Feb2021 for Covid-19 immunisation and Unspecified steroid shot. Stated reaction was three to four days. First shot got caller and patient down for a week. Second shot got caller down for three days. At first, patient's reaction was running like hers. Patient had a dry cough on an unspecified date in 2021. Was going for a COVID test today. Last week patient started running a fever on an unspecified date in 2021 and his legs were extremely weak on 14Apr2021. Has to hold onto something to go through the house on 14Apr2021. He was moving a little better, but not much. Patient had to go to doctor for his foot. Has terrible arthritis in the big toe on his right foot. Gets steroid shot every three months. Three weeks and four days after second COVID shot everything seemed to have worn off. The PA put the shot in his foot and it bruised the patient. Patient still has bruises on an unspecified date in 2021. Got the steroid shot in his big toe and two days later the weakness hit a second time. It really wiped him out. Caller cannot help patient get up and down. Patient was struggling with his legs and was aching. Wants to know if a steroid shot on top of the COVID shot and that close after would cause another reaction? The PA said it was ok to get a steroid shot three weeks after. Patient started having these reactions and doesn't know if it was the COVID shot. Has had steroid shots every 3 months for 4 years. Has never had this kind of reaction. Patient didn't think about getting the steroid shot because he seemed to be feeling fine. Reaction started the next morning and it was even worse on an unspecified date in 2021. By the third day after the shot he was down and caller couldn't help patient get up. It scared the caller. Patient also broke out in a rash across his shoulders and down both arms. States her husband has had both shots and he has been having issues since the second one n 19MAR2021. Reporter states 3 weeks and 4 days after the second vaccine, her husband had to have a steroid shot in his foot because he has terrible arthritis in his right foot. Reporter states the patient has had a flare up since then with weakness in his legs and a rash on his chest. States the only difference this time is that he had just had the second Covid vaccine 3 weeks prior. States he has not had steroid reactions in the past, and she feels like this reaction was because of the Covid vaccine. Clarifies the shot in his foot was on 13Apr2021 and she does not know what steroid was injected. States it was 3weeks and 4 days between the steroid injection and the vaccine. States maybe they should war people not to get a steroid shot for a longer time after the vaccine. States after the first vaccine for about 5 days they were just laid out. States they ate soup and whatever they could warm up in the microwave. States his ear doctor said if they reacted to the first shot they must have had Covid at sometimes. States she doesn't know, they never got tested before but they didn't have any symptoms. States her husband's test yesterday was negative. Weakness in the Legs AE: States for the last 2 days, he could not even get up on his own and she can't lift him because he was bigger than she was. Rash was states it was not itching or anything, just a rash. States it was odd because she has had hives, and this was just broken out. Clarifies the rash was across his upper back, chest, and down both arms on 14Apr2021. States it was kind of like speckled on his body like the measles on an unspecified date in 2021. States the patient was 74 years old and he had measles when he was a kid just like she did, so it is not the measles. States the patient had a Covid 19 test done yesterday and it came back negative, so he doesn't have Covid. She doesn't know what it was. Treatment: states he was taking Motrin for the Aching. States she does not know if the reaction was because the PA did the injection, it had always been the doctor that had given the injection. Caller states she thinks it was getting the steroid injection on top of receiving the Covid shot. States the both received their vaccines because they couldn't get a shot because they weren't giving shots at her age, so when offered them the vaccine, they jumped on it. Yes, last Monday to his Nurse Practitioner, did not address the weakness in his legs because did not know what to do for that. She did not even say what she thought it was, said he needed to see someone about that but does not know who to see, does not know whether to go to the ER or who to go to. Not that emergent but when doctor does not know what to treat with worrisome. She was calling about to finish the report and to speak with the Medical department regarding if this has been reported before or if any information on the Covid vaccine and steroid injections. He received the 1st dose on 26Feb2021 and the 2nd dose on 19Mar2021. She mentioned that both of them experienced achiness, sore all over after the 1st dose and flu-like symptoms on an unspecified date in 2021 after both doses. Her husband however, had muscle weakness on his legs after the 2nd dose. On 13Apr2021, about 3 weeks and 4 days after the 2nd dose, her husband received a steroid shot on his right foot. They noticed that the weakness on his legs became extreme, to which he had trouble standing up and has to hold on to something to stand up as he cannot support himself. He also had a rash on his trunk, back, and down his arms. She mentioned that the rash was not itchy but was speckled like measles. They were wondering if this has been reported and if it was possibly an interaction between the vaccine and steroid. They mentioned that they already consulted with their HCP but said that they really cannot tell. Outcome of his legs were extremely weak, has to hold onto something to go through the house was not recovered while with other event rash is across his upper back, chest, and down both arms, Achy all over was recovered on 22Mar2021 and flu-like symptoms after both doses and Sore all Over was recovered on an unspecified date in 2021, while with other events was unknown.  Follow up attempts were needed. Further information is expected.