severe asthma attack/had an exacerbation of her asthma; Lethargy, with weakness; Lethargy, with weakness; Nausea; This is a spontaneous report received from a contactable reporter(s) (Consumer or other non HCP) from medical information team. The reporter is the patient.  A 65-year-old female patient received BNT162b2 (BNT162B2), on 26May2021 as dose 2, single (Lot number: ER8734) at the age of 65 years for covid-19 immunisation. The patient's relevant medical history included: "asthma" (unspecified if ongoing), notes: Caller reports history of severe asthma; "allergies to shellfish" (ongoing), notes: Allergies, From: Caller states the allergies started at different times. , Allergies to: Eggs, Iodine, Shellfish, Nuts and Salicylate.; "Allergies to Salicylate" (ongoing), notes: Allergies, From: Caller states the allergies started at different times. , Allergies to: Eggs, Iodine, Shellfish, Nuts and Salicylate.; "Allergies to Eggs" (ongoing), notes: Allergies, From: Caller states the allergies started at different times. , Allergies to: Eggs, Iodine, Shellfish, Nuts and Salicylate.; "Allergies to Nuts" (ongoing), notes: Allergies, From: Caller states the allergies started at different times. , Allergies to: Eggs, Iodine, Shellfish, Nuts and Salicylate.; "anaphylactic shock" (unspecified if ongoing), notes: Caller also states she had anaphylactic shock to Penicillin; "Allergies to Iodine" (ongoing), notes: Allergies, From: Caller states the allergies started at different times. , Allergies to: Eggs, Iodine, Shellfish, Nuts and Salicylate. There were no concomitant medications. Vaccination history included: covid-19 vaccine (DOSE 1; Lot Number: EW0161; Route and Anatomical Location: unknown; Expiry Date: unknown), administration date: 05May2021, when the patient was 65-year-old, for COVID-19 immunization. The following information was reported: LETHARGY (non-serious), ASTHENIA (non-serious) all with onset May2021, outcome "recovered" (2021) and all described as "Lethargy, with weakness"; NAUSEA (non-serious) with onset May2021, outcome "recovered" (2021); ASTHMA (non-serious) with onset May2021, outcome "recovered" (2021), described as "severe asthma attack/had an exacerbation of her asthma".  Additional information: The reporter was asking if it is safe for her to take Prevnar 20 and if these ingredients can be found in the product. Pfizer does not specifically manufacture or test Prevnar 20 to be free of eggs, nuts, and iodine. Therefore, we cannot guarantee absence of trace amounts. The reporter stated that she took Prednisone for 10 days after a severe asthma attack. The reporter was asking if she can still take Prevnar 20 after taking Prednisone and if taking Prednisone for 10 days after a severe asthma attack may affect the efficacy/safety of the vaccine. The reporter was stated that she was prescribed Prednisone for 10 days after the asthma attack also stated that exacerbation of her asthma went on for 2 weeks after the vaccine, nausea was started a day 2 or 3 after the vaccine and lasted for 2 or 3 days and lethargy, with weakness was started a day 2 or 3 after the vaccine and it lasted about 10 days. The reporter stated that she did not take Prednisone for the event that she was reporting on today, she does generally get Prednisone to treat a bad asthma attack, and that was the reason she was calling with a question today about the Covid vaccine. The events not resulted in emergency room or physician visit. There were no other vaccinations within four weeks prior to the first administration date of the suspect vaccine and no AE following prior vaccination.