started to speak gibberish and was taken to the emergency room; out of it; combative; started to speak gibberish and was taken to the emergency room; out of it; combative; She can't remember anything after the emergency room/She has no recollection; This is a spontaneous report from a contactable consumer (patient).   A 81-year-old female patient received second dose of BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE), at the age of 81-year-old via an unspecified route of administration, administered in the left arm on 04Mar2021 (Batch/Lot number was not reported) as single dose for covid-19 immunisation.  Medical history included diabetes mellitus, blood pressure abnormal. There was no other vaccinations within four weeks prior to the first administration. Concomitant medications included ongoing metformin taken for diabetes mellitus; lisinopril taken for blood pressure abnormal, both taking for quite a while; at least a few years.  The patient previous took first dose of BNT162B2 at the age of 81-year-old via an unspecified route of administration, administered in the left arm on an unspecified date as single dose for covid-19 immunisation. The patient experienced started to speak gibberish and was taken to the emergency room; out of it; combative on 06Mar2021. Caller stated she was perfectly fine and healthy prior and up to that time and the day after. Caller stated on Saturday she got up in the morning and was talking to a friend when all of a sudden something was going wrong. Caller thanked God she was at a friend's because if she had been home she would have died. Caller stated she was rushed to the ER and after 3 MRIs that confirmed that she was not having a stroke or something similar. Caller stated she spent 6 days in ICU and 2 weeks in a rehab center, went back to friends house for another week, before she went home because she was not comfortable being home by herself because she was to take her blood pressure often. Caller stated she was perfectly fine after the first shot and after the second one. It was 2 days and she had this terrible reaction and it was the only thing it can be put down to so everything else had come up normal. On 06Mar2021, caller explained she was actually getting ready to groom one of her dogs. She got up and felt fine and she was talking to her friend and another one of her friends and all of a sudden she started to talk gibberish, so her friend asked if she was having a stroke.  Her friend took the caller's blood pressure and said they were going to the hospital and her friend took her to the emergency room. Caller stated that was all she can recall. She can't remember anything after the emergency room. According to her friend, caller was out of it, getting combative, and all kinds of stuff going on. She had no recollection, she remembered getting in the car to go to the hospital, but then had no recollection. Caller stated she just went to see the doctor a week ago and got a good bill of health. The doctor said she was pretty much good; she's improved.  Caller stated her doctor told her she did not have a stroke and they did not definitively know what happened; the only thing she can put it down to was a reaction to the Pfizer COVID-19 vaccine. The outcome was recovering.   Information about the Lot/batch number has been requested.