Hospitalized 13 hours after vaccine with blood pressure of 195/118, resting HR of 170 bpm, and chest pain; Body aches daily that worsen at night; Hospitalized 13 hours after vaccine with blood pressure of 195/118, resting HR of 170 bpm, and chest pain; Extremely elevated C-reactive protein blood work result; Atrial fibrillation diagnoses; Axillary lymph node swelled the the size of a golf ball after dose 2 and remains the same size to this day; Other vaccine same date vaccine date 15Apr2022,Other vaccine same date dose number 1; This is a spontaneous report received from a contactable reporter(s) (Consumer or other non HCP). The reporter is the patient.  A 24-year-old female patient (not pregnant) received BNT162b2 (BNT162B2), on 15Apr2022 at 11:00 as dose 2, single (Batch/Lot number: unknown) at the age of 24 years, in left arm for covid-19 immunisation. The patient had no relevant medical history. The patient took concomitant medications. Vaccination history included: Covid19 vaccine (Dose Number: 1, Batch/Lot No: Unknown. Unable to locate or read the details, Location of injection: Arm Left), for covid-19 immunization. The following information was reported: ATRIAL FIBRILLATION (hospitalization, medically significant, life threatening) with onset 01May2022 at 12:00, outcome "not recovered", described as "Atrial fibrillation diagnoses"; LYMPHADENOPATHY (hospitalization, life threatening) with onset 01May2022 at 12:00, outcome "not recovered", described as "Axillary lymph node swelled the the size of a golf ball after dose 2 and remains the same size to this day"; PAIN (hospitalization, disability, life threatening) with onset 01May2022 at 12:00, outcome "not recovered", described as "Body aches daily that worsen at night"; C-REACTIVE PROTEIN INCREASED (hospitalization, disability, life threatening) with onset 01May2022 at 12:00, outcome "not recovered", described as "Extremely elevated C-reactive protein blood work result"; HYPERTENSION (hospitalization, disability, life threatening), CHEST PAIN (hospitalization, disability, life threatening) all with onset 01May2022 at 12:00, outcome "not recovered" and all described as "Hospitalized 13 hours after vaccine with blood pressure of 195/118, resting HR of 170 bpm, and chest pain"; PRODUCT USE ISSUE (non-serious), outcome "unknown", described as "Other vaccine same date vaccine date 15Apr2022,Other vaccine same date dose number 1". The patient was hospitalized for pain, chest pain, c-reactive protein increased, atrial fibrillation, lymphadenopathy (hospitalization duration: 1 day(s)). The events "hospitalized 13 hours after vaccine with blood pressure of 195/118, resting hr of 170 bpm, and chest pain", "body aches daily that worsen at night", "extremely elevated c-reactive protein blood work result", "atrial fibrillation diagnoses" and "axillary lymph node swelled the the size of a golf ball after dose 2 and remains the same size to this day" required physician office visit and emergency room visit. The patient underwent the following laboratory tests and procedures: Blood pressure measurement: (unspecified date) 195/118; C-reactive protein: (unspecified date) Extremely elevated, notes: Extremely elevated C-reactive protein blood work result; Heart rate: (unspecified date) 170 bpm; SARS-CoV-2 test: (23Dec2021) Positive, notes: Nasal Swab. Therapeutic measures were taken as a result of hypertension, pain, chest pain, c-reactive protein increased, atrial fibrillation, lymphadenopathy. patient was treated and prescribed treatment with carvedilol and amlodipine. Clinical course: If Covid prior vaccination: No, No known allergies. Other medical history: None. Other vaccine same date vaccine location: Left arm. If other vaccine in four weeks: No. other medications in two weeks: Nikki Birth Control. The patient was hospitalized for 13 hours after vaccine with blood pressure of 195/118, resting HR of 170 bpm, and chest pain- chronic hypertension to this day with no history of hypertension. Body aches daily that worsen at night. Extremely elevated C-reactive protein blood work result - Atrial fibrillation diagnoses (no history of this, symptoms only started day of dose 2). Axillary lymph node swelled the size of a golf ball after dose 2 and remains the same size to this day. Awaiting biopsy.   No follow-up attempts are possible; information about lot/batch number cannot be obtained. No further information is expected.