LEFT ANKLE SWELLING (LEFT ANKLE APPEAR PUFFY SUCH THAT CAN NOT SEE THE BONES AND LOOKS THIRD BIGGER THAN THE RIGHT ANKLE); LEFT ANKLE PAIN ( FEELS LIKE A CONSTANT THROB, 7/10 PAIN LEVEL, PAIN FELT SHARP WHEN STANDS OR GOES DOWN THE STAIRS); TOP OF THE LEFT FOOT LOOKED DISCOLORED LIKE A LIGHT BRUISE/PURPLE; WANTED TO SLEEP; LEFT FOOT FELT STRAINED IN THE TOP ARCH; REALLY TIRED; SLIGHTLY NAUSEATED; TENDOR TO TOUCH; TENDER RIGHT ARM/LEFT FOOT PAIN/LEFT FOOT FELT TENDER AND MOVED TO THE ENTIRE LEFT ANKLE; RIGHT ARM THROBBED FOR 5 MINUTES AT THE INJECTION SITE; FEELS LIKE A BRUISE THAT'S 2 WEEKS OLD; This spontaneous report received from a patient concerned a 67 year old female. The patient's weight was 180 pounds, and height was 66 inches. The patient's past medical history included: covid-19 infection, and concurrent conditions included: mold allergy, and heavy metals allergy, and other pre-existing medical conditions included: The patient had not taking daily medications. The patient received covid-19 vaccine ad26.cov2.s (suspension for injection, route of admin not reported, batch number: 202A21A, and expiry: UNKNOWN) dose was not reported, administered on 08-SEP-2021 for prophylactic vaccination. No concomitant medications were reported. On 08-SEP-2021, the patient experienced right arm throbbed for 5 minutes at the injection site. On 08-SEP-2021, the patient experienced feels like a bruise that's 2 weeks old. On 08-SEP-2021, the patient experienced tender right arm/left foot pain/left foot felt tender and moved to the entire left ankle. On 08-SEP-2021, the patient experienced tendor to touch. On 09-SEP-2021, the patient experienced wanted to sleep. On 09-SEP-2021, the patient experienced left foot felt strained in the top arch. On 09-SEP-2021, the patient experienced really tired. On 09-SEP-2021, the patient experienced slightly nauseated. On 10-SEP-2021, the patient experienced top of the left foot looked discolored like a light bruise/purple. On 14-SEP-2021, the patient experienced left ankle swelling (left ankle appear puffy such that can not see the bones and looks third bigger than the right ankle). On 14-SEP-2021, the patient experienced left ankle pain ( feels like a constant throb, 7/10 pain level, pain felt sharp when stands or goes down the stairs). Laboratory data (dates unspecified) included: Pain scale (NR: not provided) 7/10. The action taken with covid-19 vaccine ad26.cov2.s was not applicable. The patient recovered from right arm throbbed for 5 minutes at the injection site on 08-SEP-2021, left foot felt strained in the top arch, and really tired, and slightly nauseated on 10-SEP-2021, was recovering from top of the left foot looked discolored like a light bruise/purple, had not recovered from tender right arm/left foot pain/left foot felt tender and moved to the entire left ankle, left ankle swelling (left ankle appear puffy such that can not see the bones and looks third bigger than the right ankle), left ankle pain ( feels like a constant throb, 7/10 pain level, pain felt sharp when stands or goes down the stairs), feels like a bruise that's 2 weeks old, and tendor to touch, and the outcome of wanted to sleep was not reported. This report was non-serious.