got the series of 2 doses of Shingrix Vaccines in 2019 / have a raging case of Shingles/ suspected vaccination failure; raging case of Shingles; rash / started in one side of the back and then it spread to the front of the left-hand side; Bumps; fever / got "real bad" / fever of 102; This case was reported by a consumer via call center representative and described the occurrence of suspected vaccination failure in a 78-year-old female patient who received Herpes zoster (Shingrix) for prophylaxis.   Co-suspect products included Herpes zoster (Shingrix) for prophylaxis, COVID-19 VACCINE for prophylaxis and COVID-19 VACCINE for prophylaxis.   Concurrent medical conditions included diabetes and rheumatoid arthritis.   On an unknown date, the patient received the 2nd dose of Shingrix, the 1st dose of Shingrix, the 1st dose of COVID-19 VACCINE and the 2nd dose of COVID-19 VACCINE. In April 2021, more than a year after receiving Shingrix and Shingrix, the patient experienced raised rash. On 17th April 2021, the patient experienced fever. On 21st April 2021, the patient experienced rash. On an unknown date, the patient experienced vaccination failure (serious criteria GSK medically significant) and shingles. The patient was treated with antivirals nos (Antiviral (Drug Name Unknown)). On an unknown date, the outcome of the vaccination failure, shingles and raised rash were unknown and the outcome of the fever was recovered/resolved and the outcome of the rash was not recovered/not resolved.   It was unknown if the reporter considered the vaccination failure, shingles, fever, rash and raised rash to be related to Shingrix and Shingrix.  Additional details were reported as follows: The case was reported by the patient herself. The age at vaccination was not reported but could be 75 or 76 years. The patient did not have an episode of shingles before the vaccine and this was the 1st time she got shingles. The patient got series of 2 doses of Shingrix vaccine in 2019. The patient had her 2 Covid vaccine doses in 2021 (did not provide the dates of the vaccinations). The patient reported that she had the raging case of Shingles. The patient first had the fever and when the fever went away the rash came up. The patient had that the week prior to the reporting at night the fever started and on Sunday it hot real bad. The patient had fever of 102 degree farenheit for 4 days and then had the bumps. The patient by the next Wednesday the side of the back and then it spread to the front of the left hand side. The patient was prescribed an antiviral. The patient had been taking it for 8 days now and had the rash and it has not gotten any better. The patient's physician told her that, it was shingles season, so it might have occurred. In April 2021, between 2 and 3 months after receiving COVID-19 vaccine and COVID-19 vaccine, the patient experienced raised rash. On 17th April 2021, less than 4 months, the patient experienced fever. On 21st April 2021, less than 4 months, the patient experienced rash. It was unknown if the reporter considered the fever, rash and raised rash to be related to COVID-19 vaccine  and COVID-19 vaccine. This case was considered as suspected vaccination failure as laboratory confirmation for shingles was unknown at the time of reporting.  The reporter consented to follow up. The reporter did not know the vaccination dates, or expiration dates or in which arm she got the vaccine. This case was one of 4 linked cases, reported by the same reporter.; Sender's Comments:  US-GLAXOSMITHKLINE-US2021AMR095204:same reporter US-GLAXOSMITHKLINE-US2021AMR095205:same reporter US-GLAXOSMITHKLINE-US2021AMR095201:same reporter