Brain swelling; with insomnia as I couldn't sleep; pain; I had felt like my brain was pressing up against my skul; This spontaneous case was reported by a consumer and describes the occurrence of BRAIN OEDEMA (Brain swelling) in a 30-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     The patient's past medical history included COVID-19 (felt like my brain was pressing up against my skull, I was constipated, unable to urinate, and experiencing all other common side effects of the virus.) on 16-Dec-2021.    On 26-Dec-2021 at 9:00 AM, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. In December 2021, the patient experienced BRAIN OEDEMA (Brain swelling) (seriousness criterion medically significant), INSOMNIA (with insomnia as I couldn't sleep), PAIN (pain) and FEELING ABNORMAL (I had felt like my brain was pressing up against my skul). At the time of the report, BRAIN OEDEMA (Brain swelling), INSOMNIA (with insomnia as I couldn't sleep), PAIN (pain) and FEELING ABNORMAL (I had felt like my brain was pressing up against my skul) outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On 16-Dec-2021, SARS-CoV-2 test positive: positive (Positive) Positive.     mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown) dosing remained unchanged.       Concomitant medication included woke AF preworkout 2 sccops/day.  He had originally contracted the coronavirus and he had felt like his brain was pressing up against my skull, he was constipated, unable to urinate, and experiencing all other common side effects of the virus. These symptoms left him with insomnia as he couldn't sleep through the pain and at one point he thought he had actually died. When he took the first dose of the vaccine it was on a Friday, and he worked until midnight although he was very ill and was experiencing all the symptoms again. The swelling of his brain was not as severe as the initial time when he had contracted the actual virus, but it was similar. The pain and symptoms experienced during the first dose was not nearly equivalent to the virus itself, but was horrendous none the less and left him with insomnia. COMPANY COMMENT : This spontaneous case concerns a 30 years old male with relevant medical history of COVID-19 ((felt like my brain was pressing up against my skull, I was constipated, unable to urinate, and experiencing all other common side effects of the virus) 10 days before the current vaccination, who experienced the serious unexpected event of brain oedema which occurred after the first dose of mRNA-1273 vaccine ,after taking first dose of vaccine  and I worked until midnight although I was very ill and was experiencing all the symptoms again. The swelling of my brain was not as severe as the initial time when I had contracted the actual virus, but it was similar. The pain and symptoms experienced during the first dose was not nearly equivalent to the virus itself, but was horrendous none the less and left me with insomnia. history of COVID-19 ((felt like my brain was pressing up against my skull, I was constipated, unable to urinate, and experiencing all other common side effects of the virus) remains as confounding .The benefit-risk relationship of the mRNA-1273 vaccine is not affected by this report.   This case was linked to MOD-2022-462587 (Patient Link).; Sender's Comments: This spontaneous case concerns a 30 years old male with relevant medical history of COVID-19 ((felt like my brain was pressing up against my skull, I was constipated, unable to urinate, and experiencing all other common side effects of the virus) 10 days before the current vaccination, who experienced the serious unexpected event of brain oedema which occurred after the first dose of mRNA-1273 vaccine ,after taking first dose of vaccine  and I worked until midnight although I was very ill and was experiencing all the symptoms again. The swelling of my brain was not as severe as the initial time when I had contracted the actual virus, but it was similar. The pain and symptoms experienced during the first dose was not nearly equivalent to the virus itself, but was horrendous none the less and left me with insomnia. history of COVID-19 ((felt like my brain was pressing up against my skull, I was constipated, unable to urinate, and experiencing all other common side effects of the virus) remains as confounding .The benefit-risk relationship of the mRNA-1273 vaccine is not affected by this report.