Bruised and scraped from scratching; Soreness at the injection site; Crazy random bouts of itching/Phantom itching/Itching all over including her thighs, arms, legs, torso, and head/ Phantom itching; Not wanting to eat; Felt pretty crappy/Complete blur/Feel like a train had hit her; Uncontrollable chills; Fever of 101/Fever climbed up to 102/Fever of 103.5; Whole body started uncontrollably shaking; Felt freezing and super hot; Sweating at different times during the day; This spontaneous case was reported by a consumer and describes the occurrence of HYPERPYREXIA (Fever of 101/Fever climbed up to 102/Fever of 103.5) in a 61-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 004M20A and 030L20A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     No Medical History information was reported.   On 22-Jan-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 19-Feb-2021 at 9:00 AM, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 19-Feb-2021 at 7:00 PM, the patient experienced HYPERPYREXIA (Fever of 101/Fever climbed up to 102/Fever of 103.5) (seriousness criterion medically significant), TREMOR (Whole body started uncontrollably shaking), FEELING OF BODY TEMPERATURE CHANGE (Felt freezing and super hot), HYPERHIDROSIS (Sweating at different times during the day) and CHILLS (Uncontrollable chills). On 20-Feb-2021, the patient experienced FEELING ABNORMAL (Felt pretty crappy/Complete blur/Feel like a train had hit her) and FEEDING DISORDER (Not wanting to eat). In March 2021, the patient experienced PRURITUS (Crazy random bouts of itching/Phantom itching/Itching all over including her thighs, arms, legs, torso, and head/ Phantom itching). On an unknown date, the patient experienced CONTUSION (Bruised and scraped from scratching) and VACCINATION SITE PAIN (Soreness at the injection site). The patient was treated with PRAMOCAINE HYDROCHLORIDE (CERAVE ITCH RELIEF) for Adverse event, at an unspecified dose and frequency and HYDROCORTISONE for Adverse event, at an unspecified dose and frequency. On 21-Feb-2021, HYPERPYREXIA (Fever of 101/Fever climbed up to 102/Fever of 103.5), TREMOR (Whole body started uncontrollably shaking), FEELING OF BODY TEMPERATURE CHANGE (Felt freezing and super hot), HYPERHIDROSIS (Sweating at different times during the day) and CHILLS (Uncontrollable chills) had resolved. On 28-Feb-2021, FEELING ABNORMAL (Felt pretty crappy/Complete blur/Feel like a train had hit her) had resolved. At the time of the report, PRURITUS (Crazy random bouts of itching/Phantom itching/Itching all over including her thighs, arms, legs, torso, and head/ Phantom itching) was resolving and FEEDING DISORDER (Not wanting to eat), CONTUSION (Bruised and scraped from scratching) and VACCINATION SITE PAIN (Soreness at the injection site) outcome was unknown.            No concomitant  informations were reported. The patient visited dermatologist who thought that she had beat the crap out of myself because she was bruised and scraped from scratching.  Company comment: This case concerns a 61 year-old female patient with no reported medical history who experienced the unexpected serious event of hyperpyrexia. The event occurred approximately 1 day after the second dose of Moderna COVID-19 Vaccine. The rechallenge was not applicable as no additional dosing will be administered. The benefit-risk relationship of Moderna COVID-19 Vaccine is not affected by this report.   This case was linked to MOD-2021-373075 (Patient Link).; Sender's Comments: This case concerns a 61 year-old female patient with no reported medical history who experienced the unexpected serious event of hyperpyrexia. The event occurred approximately 1 day after the second dose of Moderna COVID-19 Vaccine. The rechallenge was not applicable as no additional dosing will be administered. The benefit-risk relationship of Moderna COVID-19 Vaccine is not affected by this report.