there is some sort of inflammation going on with that.; CPK test is strange; facial sagging, sagging eyelids went away/Neurological inflammation went away/Pain went away; flushing; Warmth; Low grade fever; This is a spontaneous report from a contactable consumer (patient).   A 53-years-old female patient received bnt162b2 (PFIZER-BIONTEC COVID-19 VACCINE, Solution for injection), dose 1 via an unspecified route of administration, administered in Deltoid Left on 10Apr2021 (Batch/Lot Number: EW0153) as SINGLE DOSE for covid-19 immunisation. Patient did not receive Other medications in two weeks of vaccination. Medical history included sjogren's syndrome from 2002 and ongoing. Patient stated dry eyes and dry mouth were part of this diagnosis and less lubricating fluid in joints which gets worse as you age. patient is not sure if her body destroying her peripheral nervous system is part of this syndrome, it is still idiopathic. Unknown if peripheral neuropathy is associated with this syndrome, raynaud's syndrome about 2002, give or take 1 or 2 years at the Medical Center, ongoing, postural orthostatic tachycardia syndrome (2002), patient feet would turn red, white and blue. In order to do nerve conduction studies, they have to put her hands and feet in warm water to bring up the temperature to get accurate results, ongoing, allergy Started since she was a child. Patient states she has allergies to about 40 different medications, anaphylactic reaction to Naprosyn sodium, allergic to Atarax. Levaquin is bad and Patient lost consciousness, had to have CT done to see if Patient suffered a concussion, her blood pressure plummeted, ongoing, hypermobility syndrome diagnosed about 2-3 years ago. This is also referred to as double jointedness and can also be looked at as a connective tissue disease. It has wide range of effects on the body, ongoing, arthritis unsure of what type, doctors are discussing rheumatoid, Peripheral Rheumatoid Arthritis. Has had for quite a while. Has had aches and pains for so long. Since Patient early 30's. Maybe 1998. Contractures showing up in her hands they are thinking it is some form of rheumatoid or other autoimmune arthritis, possibly osteo. It is becoming far more pronounced, ongoing. Seizure Verbatim: Nocturnal seizures Class 3, left temporal lobe where abnormal electrical activity was found. About 10 years ago, rapid eye movement sleep behaviour disorder from 2002 and ongoing. Rapid eye movement sleep behavior disorder Diagnosed in 2002. Patient acts out her dreams. Diagnosed from sleep study, ongoing. Thrombocytopenia Verbatim: Thrombocytopenia physician watching her for this since the beginning of 2021. Doctors are watching her platelets. Patient bruises easy and because patient is at the age her mother was diagnosed. Patient mother has a history of Thrombocytopenia. History of this disorder with the females on her mother's side, mother and grandmother. Could be a genetic variant, ongoing, hypothyroidism thyroid nodules crushed her thyroid. Diagnosed 5 years ago and has to take Synthroid, endometriosis Connective Tissue Disorder, abnormal cavity. Diagnosed about 6-7 years ago. Had a Hysterectomy. Doctors could not find one ovary and one fallopian tube. Its all over her intestines. Patient had allergies of Plaquenil, antihistamines and non-steroidal antinflammatories, urinary tract infection and patient had Flu shot vaccine and had a sore arm. Concomitant medication included levothyroxine sodium (SYNTHROID) taken for an unspecified indication, start and stop date were not reported. After she received the covid vaccine on 10 Apr 2021, she felt warm for a change. She could feel her eyes opening up and noticed her hands, shoulder, back and joints do not hurt. There are some joints in her hands that have scar tissue with a bump, her hands were no longer red or purple and swelling started to recede. Hands are no longer swollen or red. Out of all the different treatments, this has never happened. She still does not have redness or swelling. She is scheduled for her second vaccine on 01May2021. Caller stated she has not started any new medication 2 weeks prior to the vaccine or any after the vaccine. She is on palliative care and there are medications that she takes on daily basis. She has been on the same doses. Reports she revamped her own medications in the past because she felt like she was being overmedicated. She got rid of a bunch of junk last year and somethings she added back in at a much lower dose. No further details provided. Blood tests don't catch everything since she is genetically predisposed to giving false negatives. If she is in a flare up, the c reactive protein test, in the past, it always came in normal and now it is documented there is some sort of inflammation going on with that. Her CPK test is strange, it is a test for destruction of muscle tissue, 600 is considered high and she has scored as high as 3000. A lot of stuff going on and it is hard to separate when technology and research is not there yet.  Her symptoms are treated as they emerge. The patient's facial sagging, sagging eyelids went away/neurological inflammation went away/pain went away. The patient experienced flushing, warmth/low grade fever on 10Apr2021, there is some sort of inflammation going on with that on an unspecified. CPK test was strange on an unspecified date. Outcome of flushing and warmth/low grade fever was resolved, and outcome of all other events was unknown.   No follow up attempts are possible, no further information is expected.