No adverse event; Patient received a full dose of the vaccine as dose 3; Patient has not had any outbreaks of herpes since receiving that dose over the past 2.5 years; This spontaneous case was reported by a patient and describes the occurrence of THERAPEUTIC RESPONSE UNEXPECTED (Patient has not had any outbreaks of herpes since receiving that dose over the past 2.5 years), ACCIDENTAL OVERDOSE (Patient received a full dose of the vaccine as dose 3) and NO ADVERSE EVENT (No adverse event) in a 62-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 011J20A, 030L20A and 023C21A) for COVID-19 prophylaxis.     The patient had received vaccines in the 4 weeks prior to COVID-19 vaccine.  Previously administered products included for Product used for unknown indication: Flu vaccine (Patient received the flu vaccine every year). Past adverse reactions to the above products included No adverse event with Flu vaccine. Concurrent medical conditions included Oral herpes (simplex 1, patient was able to control it with acyclovir for years, but would have some breakouts irregularly.) since 1997. Concomitant products included ACYCLOVIR [ACICLOVIR] for Oral herpes.   On 30-Dec-2020, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. On 27-Jan-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 06-Aug-2021, received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On an unknown date, the patient received fourth dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 30-Dec-2020, the patient experienced THERAPEUTIC RESPONSE UNEXPECTED (Patient has not had any outbreaks of herpes since receiving that dose over the past 2.5 years). On 06-Aug-2021, the patient experienced ACCIDENTAL OVERDOSE (Patient received a full dose of the vaccine as dose 3). On an unknown date, the patient experienced NO ADVERSE EVENT (No adverse event). At the time of the report, THERAPEUTIC RESPONSE UNEXPECTED (Patient has not had any outbreaks of herpes since receiving that dose over the past 2.5 years), ACCIDENTAL OVERDOSE (Patient received a full dose of the vaccine as dose 3) and NO ADVERSE EVENT (No adverse event) outcome was unknown.        For mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown), the reporter considered NO ADVERSE EVENT (No adverse event) to be not related. No further causality assessments were provided for THERAPEUTIC RESPONSE UNEXPECTED (Patient has not had any outbreaks of herpes since receiving that dose over the past 2.5 years) and ACCIDENTAL OVERDOSE (Patient received a full dose of the vaccine as dose 3).    It was reported that patient received 5 doses of COVID-19 vaccines including 2 additional booster doses. For the third full dose on 6-Aug-2021 patient lied to the vaccination provider about having received any previous doses of the COVID-19 vaccines to receive an additional primary series dose. Patient then received an additional booster dose on an unknown date of the Moderna vaccine. The patient also received a bivalent Pfizer covid-19 vaccine booster dose.  No treatment medication was provided.