This case was reported by a consumer via call center representative and described the occurrence of muscle pain in a 78-year-old female patient who received SHINGRIX for prophylaxis. On 2nd June 2018, the patient received the 1st dose of SHINGRIX. On 3rd June 2018, 1 days after receiving SHINGRIX, the patient experienced erythematous rash, nervous and fear. In June 2018, the patient experienced muscle pain, general body pain, influenza-like symptoms, feeling unwell and skin discoloration. In June 2018, the outcome of the muscle pain, general body pain, influenza-like symptoms and feeling unwell were recovered/resolved. On an unknown date, the outcome of the erythematous rash was recovering/resolving and the outcome of the nervous and fear were unknown and the outcome of the skin discoloration was not recovered/not resolved. It was unknown if the reporter considered the muscle pain, general body pain, influenza-like symptoms, erythematous rash, nervous, feeling unwell, fear and skin discoloration to be related to SHINGRIX. Additional details were provided as follows: The patient reported on 4th June 2018 that she not only had very bad side effect from the vaccine of lots of muscle aches and feeling like achy as though she had a bad flu but also now has a rash on her face which was like an oblong streak along her cheekbone which was moving a little toward her eye which made her very nervous. The rash looked a lot to her like the pictures she has previously seen of shingles. She did not think one could get shingles from a shingles vaccination and has never had shingles. She did get the old vaccination several years before the reporting date, like might be 8 years before and thought she should definitely get this new vaccine. The patient said she would be going to see her dermatologist in the morning on 5th June 2018 and that she thought this shingles vaccine had actually given her shingles. She requested a callback. Upon outbound call back on 5th June 2018 after listening to the voicemail, she declined due to time constraints to go through form but inquired if the symptom on her cheek could be shingles and, if so, could she be contagious to her daughter who has not had chickenpox and with whom she had been planning to visit this weekend. She described that she had gotten a very bad flu-like reaction described as being achy all over her body and really feeling very sick. Those symptoms went on for about a day and one half. And then all of the sudden she had this huge, red pimply streak on her cheek that was moving up toward the orbit around her eye which scared her. This symptom was a little better and calmer in the morning of 4th June 2018.  It had been red, angry, tiny pimply things in the streak along her cheekbone coming up to her eye orbit in the night of 3rd June 2018. A woman (a physician) who saw it that night told her this symptom of rash on her cheek was shingles. She was referred to her health care professional during the call. The patient reported on 7th June 2018 that she was seen by dermatologist on Tuesday, 5th June 2018 and was determined rash was not a shingles outbreak since the rash was resolving and there was no pain associated with it. The patient reported that now there was some slight residual discoloration on her face. The patient stated that no medicine or treatment was provided for the rash by the dermatologist. The patient also provided pharmacy information for where she had the vaccine and contact details of the dermatologist. On 8th June 2018, a physician called to follow up with an adverse event which was previously reported by the patient. The physician stated they were unsure if the rash was Shingles since it resolved after one day and was mostly resolved when the patient was seen by the physician. No additional information was provided.