neuropathy in feet; swollen hand/arm after Moderna shot; cripple had a hard time getting up; Leg weakness; Muscle soreness; This spontaneous case was reported by a patient and describes the occurrence of NEUROPATHY PERIPHERAL (neuropathy in feet) in an elderly male patient who received mRNA-1273 (Spikevax) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.    Co-suspect product included non-company product ENZALUTAMIDE capsule for Malignant neoplasm of prostate.    The patient's past medical history included Pacemaker insertion (cardiac). Concurrent medical conditions included Asthma, Chronic obstructive pulmonary disease, Hypertension, Mitral valve disease, Hyperlipidemia, Sinoatrial node dysfunction, Coronary atherosclerosis of native coronary artery, Voiding difficulty (straining to void), Osteoarthrosis, localised, primary, involving lower leg, Left heart failure and Drug allergy (Codeine phosphate powder). Concomitant products included ASPIRIN [ACETYLSALICYLIC ACID] for an unknown indication.   In March 2021, the patient ENZALUTAMIDE (Oral) dosage was changed to 160 milligram once a day. On an unknown date, the patient received dose of mRNA-1273 (Spikevax) (unknown route) 1 dosage form and ENZALUTAMIDE (Oral) 80 milligram once a day. On an unknown date, the patient experienced NEUROPATHY PERIPHERAL (neuropathy in feet) (seriousness criterion medically significant), EXTENSIVE SWELLING OF VACCINATED LIMB (swollen hand/arm after Moderna shot), HYPOKINESIA (cripple had a hard time getting up), MUSCULAR WEAKNESS (Leg weakness) and MYALGIA (Muscle soreness). The patient was treated with PREDNISONE at an unspecified dose and frequency. At the time of the report, NEUROPATHY PERIPHERAL (neuropathy in feet) was resolving and EXTENSIVE SWELLING OF VACCINATED LIMB (swollen hand/arm after Moderna shot), HYPOKINESIA (cripple had a hard time getting up), MUSCULAR WEAKNESS (Leg weakness) and MYALGIA (Muscle soreness) outcome was unknown.        The action taken with mRNA-1273 (Spikevax) (Unknown) was unknown.       Patient's past drug included unspecified blood thinner.  Patient stated that he got the Moderna shot an leg weakness started around that time.  Company comment- This spontaneous case concerns a 73-year-old male patient with relevant medical history of Prostate cancer with intake of Enzalutamide and Osteoarthrosis, who experienced unexpected, serious (medically significant) event of Neuropathy peripheral which occurred at an unknown time with regards to the mRNA-1273 vaccination. The patient received enzalutamide for prostate cancer wherein he had a change in the dose. He experienced muscle soreness and had a hard time getting up accompanied with neuropathy. The patient took prednisone which gave relief to the symptoms. The patient also complained of leg weakness and swollen hand & arm after mRNA-1273 vaccination. The outcome of the event was reported as resolving. The with relevant medical history of Prostate cancer with intake of Enzalutamide and Osteoarthrosis are confounders for the events. The benefit-risk relationship of mRNA-1273 vaccine is not affected by this report.; Sender's Comments: This spontaneous case concerns a 73-year-old male patient with relevant medical history of Prostate cancer with intake of Enzalutamide and Osteoarthrosis, who experienced unexpected, serious (medically significant) event of Neuropathy peripheral which occurred at an unknown time with regards to the mRNA-1273 vaccination. The patient received enzalutamide for prostate cancer wherein he had a change in the dose. He experienced muscle soreness and had a hard time getting up accompanied with neuropathy. The patient took prednisone which gave relief to the symptoms. The patient also complained of leg weakness and swollen hand & arm after mRNA-1273 vaccination. The outcome of the event was reported as resolving. The with relevant medical history of Prostate cancer with intake of Enzalutamide and Osteoarthrosis are confounders for the events. The benefit-risk relationship of mRNA-1273 vaccine is not affected by this report.