Immediate onset of menstruation; Intense joint pain; mild lymphnode swelling in jaw and underarms; painful migraines; mild lymphnode swelling in jaw and underarms; This is a spontaneous report received from a contactable reporter(s) (Consumer or other non HCP). The reporter is the patient.  A 23 year-old female patient (not pregnant) received bnt162b2 (BNT162B2), administration date 19Oct2021 (Batch/Lot number: unknown) as dose 1, single and administered in arm left, administration date 09Nov2021 (Batch/Lot number: unknown) as dose 2, single for covid-19 immunisation. Relevant medical history included: "Hypothyroidism" (unspecified if ongoing), notes: Other medical history: hypothyroidism; "depression" (unspecified if ongoing), notes: Other medical history: depression; "anxiety" (unspecified if ongoing), notes: Other medical history: anxiety; "connective tissue autoimmune disorder" (unspecified if ongoing), notes: Other medical history: connective tissue autoimmune disorder.; "COVID-19" (unspecified if ongoing), notes: If covid prior vaccination: Yes; "not menstruated" (unspecified if ongoing), notes: have not menstruated in 2 years. Concomitant medication(s) included: FLU taken for immunisation, administration date 19Oct2021; WELLBUTRIN; LEXAPRO; LEVOTHYROXIN. Past drug history included: Nexplanon implant, notes: I have a nexplanon implant and have not menstruated in 2 years. The following information was reported: MENSTRUATION IRREGULAR (non-serious) with onset 19Oct2021, outcome "recovering", described as "Immediate onset of menstruation"; ARTHRALGIA (non-serious) with onset 19Oct2021, outcome "not recovered", described as "Intense joint pain"; LYMPHADENOPATHY (non-serious), LYMPHADENOPATHY (non-serious) all with onset 19Oct2021, outcome "recovering" and all described as "mild lymphnode swelling in jaw and underarms"; MIGRAINE (non-serious) with onset 19Oct2021, outcome "not recovered", described as "painful migraines". The events "immediate onset of menstruation", "intense joint pain", "mild lymphnode swelling in jaw and underarms", "painful migraines" and "mild lymphnode swelling in jaw and underarms" were evaluated at the physician office visit. Therapeutic measures were not taken as a result of menstruation irregular, lymphadenopathy, lymphadenopathy. Therapeutic measures were taken as a result of arthralgia, migraine. Additional information: Other medical history :Hypothyroidism, depression/anxiety, connective tissue autoimmune disorder. No known allergies. The patient diagnosed with COVID-19, prior to vaccination and Since the vaccination, the patient has not been tested for COVID-19. Patient received other vaccine within 4weeks product was flu shot on 19Oct2021 as first dose on right arm and within 2 weeks of vaccination were welbutrin, Lexapro and levothyroxine. Facility where the most recent COVID-19 vaccine was administered was pharmacy or drug Store. Reported Event: Immediate onset of menstruation after her first and second doses (2 periods in a 3 week span). Patient had a nexplanon implant and have not menstruated in 2 years prior to receiving the vaccine. Intense joint pain and mild lymphnode swelling in jaw and underarms. Patient also experienced painful migraines after both doses. It has been over 48 hours since receiving her 2nd dose and she was still experiencing migraines and joint pain that was not mitigated by OTC pain medication. Patient have scheduled an appointment with my primary care doctor. The adverse event resulted in doctor or other healthcare professional office/clinic visit. No treatment was received for adverse events except migraine and joint pains. No follow-up attempts are possible; information about lot/batch number cannot be obtained. No further information is expected.