sever upper gastric bleeding; black tarry stools; hemoglobin numbers dropped; This is a spontaneous report received from a contactable reporter(s) (Consumer or other non HCP). The reporter is the patient.  A 51-year-old male patient received BNT162b2, BNT162b2 omi ba.4-5 (BNT162B2, BNT162B2 OMI BA.4-5), on 17Sep2022 at 12:00 as dose 5 (booster), single (Lot number: GJ2524) at the age of 51 years, in left arm for covid-19 immunization. The patient's relevant medical history was not reported. The patient took concomitant medications. Vaccination history included: BNT162b2 (Dose Number: 4, Batch/Lot No: FK9895, Location of injection: Arm Left, Vaccine Administration Time: 12:00 PM), administration date: 16Apr2022, when the patient was 50-year-old, for COVID-19 Immunization, reaction(s): "sever upper gastric bleeding", "hemoglobin numbers dropped", "black tarry stools"; BNT162b2 (Dose Number: 3, Batch/Lot No: 320308D, Location of injection: Arm Left, Vaccine Administration Time: 12:00 PM), administration date: 29Oct2021, when the patient was 50-year-old, for COVID-19 Immunization; BNT162b2 (Dose Number: 2, Batch/Lot No: FP2533, Location of injection: Arm Left, Vaccine Administration Time: 12:00 PM), administration date: 16Apr2021, when the patient was 49-year-old, for COVID-19 Immunization; BNT162b2 (Dose Number: 1, Batch/Lot No: FN6204, Location of injection: Arm Left, Vaccine Administration Time: 12:00 PM), administration date: 24Mar2021, when the patient was 49-year-old, for COVID-19 Immunization.  The following information was reported: FAECES DISCOLOURED (hospitalization, life threatening) with onset 01Oct2022 at 14:30, outcome "recovering", described as "black tarry stools"; HAEMOGLOBIN DECREASED (hospitalization, life threatening) with onset 01Oct2022 at 14:30, outcome "recovering", described as "hemoglobin numbers dropped"; GASTRIC HAEMORRHAGE (hospitalization, life threatening) with onset 01Oct2022 at 14:30, outcome "recovering", described as "sever upper gastric bleeding". The patient was hospitalized for gastric hemorrhage, faeces discolored, hemoglobin decreased (hospitalization duration: 3 day(s)). The events "sever upper gastric bleeding", "black tarry stools" and "hemoglobin numbers dropped" required emergency room visit. The patient underwent the following laboratory tests and procedures: Hemoglobin: (unspecified date) dropped from 13-14 down to 7-8, notes: dropped from 13-14 down to 7-8; multiple tests: (unspecified date) Unknown results; Esophagogastroduodenoscopy: (unspecified date) Unknown results, notes: s including multiple EGDs to try to locate the point of bleeding; SARS-CoV-2 test: (18Oct2022) Positive, notes: Nasal Swab. Therapeutic measures were taken as a result of gastric hemorrhage, faeces discolored, hemoglobin decreased. Clinical course: No other vaccine in four weeks and had Probiotic in two weeks. Adverse event: Exactly 2 weeks after each of patient's last two doses on 16Apr2022 & 17Sep2022 patient was hospitalized for sever upper gastric bleeding. This was evident from black tarry stools and hemoglobin numbers dropped from 13-14 down to 7-8. The patient was admitted both times for multi night stays and multiple tests including multiple EGDs to try to locate the point of bleeding. These both happened exactly 2 weeks after patient's Pfizer covid vax dose. Ae treatment: EGD with clips placed on poss bleed blood vessels. No covid prior vaccination and covid tested was done post vaccination. No known allergies; Sender's Comments: Linked Report(s) : US-PFIZER INC-202201398220 Same reporter/patient, same drug/different dose, same AE;US-PFIZER INC-202201398221 Same reporter/patient, same drug/different dose, different AE;