Was hospitalized after this visit where she was diagnosed as having "nerve damage."/nerve damage; She was able to ambulate with a walker at discharge, but now has been using a cane/ walker; The pain had moved from her groin towards her hip and under her knee; This pain gradually escalated and eventually became debilitating/ debilitating/This has been excruciating pain and the worst pain of her life/the worst pain of my life; 3 weeks after receiving the second dose of the vaccine she started having leg pain in her right leg towards her groin; Leg pain/3 weeks after receiving the second dose of the vaccine she started having leg pain in her right leg towards her groin; Nerve inflammation; Both of her feet felt funny and prickly/funny and prickly; Her ankle was swollen; She became unable to sit after standing at her job/she was not able to sit; This spontaneous case was reported by a consumer and describes the occurrence of NERVE INJURY (Was hospitalized after this visit where she was diagnosed as having "nerve damage."/nerve damage) in a female patient of an unknown age who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 076C21A and 009D21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     Concurrent medical conditions included Mast cell activation syndrome, Mutagenic effect (A mutation where the body cannot rid itself of toxins) and Allergy (She has a history of allergies).   On 13-Oct-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 10-Nov-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. In December 2021, the patient experienced PAIN (This pain gradually escalated and eventually became debilitating/ debilitating/This has been excruciating pain and the worst pain of her life/the worst pain of my life), GROIN PAIN (3 weeks after receiving the second dose of the vaccine she started having leg pain in her right leg towards her groin), PAIN IN EXTREMITY (Leg pain/3 weeks after receiving the second dose of the vaccine she started having leg pain in her right leg towards her groin), NEURITIS (Nerve inflammation), PARAESTHESIA (Both of her feet felt funny and prickly/funny and prickly), JOINT SWELLING (Her ankle was swollen) and SITTING DISABILITY (She became unable to sit after standing at her job/she was not able to sit). On an unknown date, the patient experienced NERVE INJURY (Was hospitalized after this visit where she was diagnosed as having "nerve damage."/nerve damage) (seriousness criterion hospitalization), WALKING AID USER (She was able to ambulate with a walker at discharge, but now has been using a cane/ walker) and ARTHRALGIA (The pain had moved from her groin towards her hip and under her knee). The patient was treated with GABAPENTIN on 16-Dec-2021 at an unspecified dose and frequency; OXYTETRACYCLINE HYDROCHLORIDE (OXY [OXYTETRACYCLINE HYDROCHLORIDE]) on 16-Dec-2021 at an unspecified dose and frequency; PREGABALIN (LYRICA) at an unspecified dose and frequency; DULOXETINE HYDROCHLORIDE (CYMBALTA) for Mobility decreased, at an unspecified dose and frequency and Physical therapy for Nerve injury. At the time of the report, NERVE INJURY (Was hospitalized after this visit where she was diagnosed as having "nerve damage."/nerve damage), PAIN (This pain gradually escalated and eventually became debilitating/ debilitating/This has been excruciating pain and the worst pain of her life/the worst pain of my life), GROIN PAIN (3 weeks after receiving the second dose of the vaccine she started having leg pain in her right leg towards her groin), PAIN IN EXTREMITY (Leg pain/3 weeks after receiving the second dose of the vaccine she started having leg pain in her right leg towards her groin), NEURITIS (Nerve inflammation), PARAESTHESIA (Both of her feet felt funny and prickly/funny and prickly), JOINT SWELLING (Her ankle was swollen), SITTING DISABILITY (She became unable to sit after standing at her job/she was not able to sit) and ARTHRALGIA (The pain had moved from her groin towards her hip and under her knee) outcome was unknown and WALKING AID USER (She was able to ambulate with a walker at discharge, but now has been using a cane/ walker) had not resolved.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On 16-Dec-2021, Blood pressure measurement: high (High) High (Elevated). On an unknown date, Blood test: results not provided. results not provided.. On an unknown date, Computerised tomogram: results not provided. results not provided.. On an unknown date, Lumbar puncture: results not provided. results not provided.. On an unknown date, Magnetic resonance imaging: results not provided. results not provided.. On an unknown date, Nerve conduction studies: results not provided. results not provided.. On an unknown date, X-ray: results not provided. results not provided..     For mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular), the reporter did not provide any causality assessments.   It was reported that 3 weeks after receiving the second dose of the vaccine she started having leg pain in her right leg towards her groin. She described this pain as nerve inflammation. The pain gradually escalated and eventually became debilitating. She saw a healthcare professional for this pain twice in early December, where her ankle was swollen and both of her feet felt funny and prickly. The second of these was on 16 Dec 2021 where she discussed elevated blood pressure with the HCP. They provided her gabapentin, oxy and steroids at the appointment. She had another doctors appointment again in December after she became unable to sit after standing at her job. That day, she was able to drive her child to school and herself to work but upon arriving at work she was not able to sit. The pain had moved from her groin towards her hip and under her knee. She was hospitalized after this visit where she was diagnosed as having nerve damage. This had been excruciating pain and the worst pain of her life. While hospitalized they ran blood tests, x rays, CT scans, and MRI with contrast. They also performed a spinal tap procedure. While in the hospital they put her on Lyrica and Cymbalta which improved her mobility while lying on the bed. They ran nerve conduction tests while there too. She was discharged where she had been using physical therapy. She was able to ambulate with a walker at discharge, but now had been using a cane. She was a young woman and exercised regularly prior to the vaccine.  This is a spontaneous case concerning a female patient of unknown age with a medical history of mast cell activation syndrome, mutagenic effect and allergy, who experienced the unexpected events of nerve injury, pain, groin pain, pain in extremity, neuritis, paraesthesia, joint swelling, walking aid user, arthralgia and sitting disability. The events occurred a few weeks after the second dose of mRNA  1273 vaccine. Nerve injury was the event which caused patient's hospitaliz; Sender's Comments: This is a spontaneous case concerning a female patient of unknown age with a medical history of mast cell activation syndrome, mutagenic effect and allergy, who experienced the unexpected events of nerve injury, pain, groin pain, pain in extremity, neuritis, paraesthesia, joint swelling, walking aid user, arthralgia and sitting disability. The events occurred a few weeks after the second dose of mRNA  1273 vaccine. Nerve injury was the event which caused patient's hospitalization and at the time of report all the events have not resolved. The reporter's assessment was not provided. The benefit-risk relationship of the vaccine is not affected by this report.