ABNORMAL WHITE BLOOD CELL COUNT; SENSE OF SMELL INTERMITTENTLY WAS ALTERED OR GONE TWICE; SENSE OF TASTE INTERMITTENTLY WAS ALTERED OR GONE TWICE; FEELING VERY COLD; SINUS INFECTION; DISORIENTATION; COULD NOT EAT; SLEPT AROUND 16 HOURS A DAY; NO APPETITE; VISUAL AND AUDITORY HALLUCINATIONS; FELT VERY FATIGUED; FEVERS GREATER THAN 101F; NAUSEA; VOMITING; FEELING WEIRD; This spontaneous report received from a patient concerned a 28 year old male. The patient's weight was 190 pounds, and height was 73 inches. The patient's concurrent conditions included: seasonal sinus infections which last usually 1-2 days but now was going on now for a month, anxiety issues, and gastrointestinal issues, and other pre-existing medical conditions included: The patient had no known allergies. The patient received covid-19 vaccine ad26.cov2.s (suspension for injection, route of admin not reported, batch number: 204A21A, and expiry: 21-SEP-2021) dose was not reported, 1 total administered to left arm on 03-MAY-2021 for prophylactic vaccination. The dose number in series was 1. Concomitant medications included cannabis sativa for anxiety issues, and gastrointestinal issue but since getting the vaccine, patient reported that on some days he can't tolerate smoking because of nausea/taste alteration, and that his taste for foods have been randomly changing.  On 03-MAY-2021, around 8at night the patient experienced feeling weird, with fevers greater than 101 Fahrenheit, nausea and vomiting as well. Laboratory data included: Body temperature (NR: not provided) Greater than 101 F. On 04-MAY-2021, the patient experienced visual and auditory hallucinations, along with no appetite and could not eat, felt very fatigued, slept around 16 hours a day, all of which lasted around 5 days. On 09-SEP-2021 and 13-SEP-2021 patient went to hospital for intractable nausea and vomiting and was given IV Zofran and also experienced some disorientation. Patient had full panels of blood work done, they were unremarkable, but white blood cells (WBC's) were abnormal and was started on Doxycycline 100mg BID for abnormal WBC's. Patient reports further that he was unable to tolerate that medication and was also given a Zofran prescription to take home. On NOV-2021, the patient experienced sinus infection, he is still congested, has been through two different antibiotics for the sinus issues and that certain smells trigger nausea and vomiting now. On an unspecified dates twice after vaccination, the patient experienced sense of smell and taste intermittently was altered or gone. On an unspecified date the patient experienced feeling very cold but the patient says he usually runs warm. Patient has been using Cannabis for GI/anxiety issues, but since getting the vaccine he reported that on some days he can't tolerate smoking because of nausea and taste alteration, and that his taste for foods have been randomly changing. The action taken with covid-19 vaccine ad26.cov2.s was not applicable. The patient recovered from visual and auditory hallucinations, no appetite, could not eat, slept around 16 hours a day, and felt very fatigued on MAY-2021, and disorientation, feeling very cold, and fevers greater than 101f, had not recovered from sinus infection, sense of smell intermittently was altered or gone twice, and sense of taste intermittently was altered or gone twice, and the outcome of abnormal white blood cell count, nausea, feeling weird and vomiting was not reported. This report was serious (Other Medically Important Condition).; Sender's Comments: V0 20211233106-COVID-19 VACCINE AD26.COV2.S- visual and auditory hallucinations. This event(s) is considered unassessable. The event(s) has a compatible/suggestive temporal relationship, is unlabeled, and has unknown scientific plausibility. There is no information on any other factors potentially associated with the event(s).  V0 20211233106-COVID-19 VACCINE AD26.COV2.S- nausea,  vomiting. This event(s) is labeled per RSI and is therefore considered potentially related.