After 3 weeks of receiving the 1st booster patient experienced a heart attack; This spontaneous case was reported by a patient and describes the occurrence of MYOCARDIAL INFARCTION (After 3 weeks of receiving the 1st booster patient experienced a heart attack) in a 58-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 012f21a, 007m20a, 039k20a and 005m21a) for COVID-19 vaccination.     Concurrent medical conditions included Allergy to antibiotic.   On 05-Jan-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 02-Feb-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 25-Oct-2021, received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 21-Apr-2022, received fourth dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 16-Nov-2021,  after starting mRNA-1273 (Moderna COVID-19 Vaccine), the patient experienced MYOCARDIAL INFARCTION (After 3 weeks of receiving the 1st booster patient experienced a heart attack) (seriousness criteria hospitalization and medically significant). The patient was hospitalized on sometime in November 2021 due to MYOCARDIAL INFARCTION. At the time of the report, MYOCARDIAL INFARCTION (After 3 weeks of receiving the 1st booster patient experienced a heart attack) had not resolved.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On 18-Jun-2022, SARS-CoV-2 test: Positive.     For mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown), the reporter did not provide any causality assessments.   No concomitant and Treatment medications were reported.  Patient has not experienced a similar event in the past. Patient stated that she was not recovered from events and she will be on medication for the rest of life. Patient had a flu shot in Dec after the heart attack. 3 stents placed to patient after hospitalization.  Company comment: This spontaneous case concerns a 58-year-old female patient, with no relevant medical history, who experienced the unexpected serious (Hospitalization, medically significant) event of MYOCARDIAL INFARCTION (After 3 weeks of receiving the 1st booster patient experienced a heart attack), about 3 weeks after receiving the 3 (booster) dose of mRNA-1273 Vaccine, in the covid 19 vaccination series, and was hospitalized for the event. It was reported that the patient had a positive covid 19 test about 4 months prior to event onset, which is a risk factor to the event. Patient had a flu shot after the heart attack and three stents were placed to patient. The event was reported as not resolved. No other information on comorbidities, risk factors, labs, diagnostics, concomitant medications and treatment details were reported. The benefit-risk relationship of mRNA-1273 Vaccine is not affected by this report.   This case was linked to MOD-2022-637944 (Patient Link).; Sender's Comments: This spontaneous case concerns a 58-year-old female patient, with no relevant medical history, who experienced the unexpected serious (Hospitalization, medically significant) event of MYOCARDIAL INFARCTION (After 3 weeks of receiving the 1st booster patient experienced a heart attack), about 3 weeks after receiving the 3 (booster) dose of mRNA-1273 Vaccine, in the covid 19 vaccination series, and was hospitalized for the event. It was reported that the patient had a positive covid 19 test about 4 months prior to event onset, which is a risk factor to the event. Patient had a flu shot after the heart attack and three stents were placed to patient. The event was reported as not resolved. No other information on comorbidities, risk factors, labs, diagnostics, concomitant medications and treatment details were reported. The benefit-risk relationship of mRNA-1273 Vaccine is not affected by this report.