severe tremors; aches; joint pain; 101.7 fever; chills; BNT162b2 dose 3 (booster); extreme fatigue; This is a spontaneous report received from a contactable consumer (patient). This consumer reported events after the first, second, and third dose of vaccine. This is the third of three reports (dose 3). A 69-year-old female patient received BNT162b2 (PFIZER-BIONTECH COVID-19 VACCINE, lot number FF2590) intramuscular in left arm on 15Oct2021 01:00 PM (at the age of 69-year-old) as dose 3 (booster), single for COVID-19 immunisation. Vaccination facility type for third dose was reported as hospital or drug store. The patient did not received any prior vaccinations within 4 weeks. The patient's medical history included high blood pressure from unspecified date and ongoing. The patient's concomitant medications included valsartan/hydrochlorothiazide (HCT), oral from unspecified date and ongoing for high blood pressure. The patient previously received BNT162b2 (lot number EL3247), intramuscular in left arm on 18Jan2021 08:30 AM as dose 1, single for COVID-19 immunization and she did not experience any reaction other than a sore arm for a day or two. She also previously received BNT162b2 (lot number EL9264), intramuscular in left arm on 08Feb2021 08:30 AM (at the age of 69-year-old) as dose 2, single for COVID-19 immunization and by 10 PM (08Feb2021), she began experiencing chills, body aches, joint pain and 101.9 fever. This lasted for 4 days followed by 100-degree fever for another day and extreme tiredness for several weeks. In light of this reaction, she was hesitant to obtain a booster shot without discussing this with a professional medical adviser. Her concern was that this was not a typical response and that she was experiencing a hyperimmune or autoimmune response. Also, Guillain-Barre syndrome crossed her mind. At that time, she did not consider that the product was defective, but rather that something in her immune system might be amiss. On 27Sep2021, while at a well-care visit, she discussed this reaction with her physician. She recommended that perhaps she could delay taking the booster if she checked her antibody titers. She was not comfortable with putting off the inevitable, taking a booster, since she was over 65 years old. The following day, she called the facility to obtain reassurance that her reaction was normal and it would be safe to make an appointment for a booster shot. She spoke to (privacy) in the medical division. She advised her to speak to her physician which she had already done and she read off a list of common reactions. She did not experience a rash, hives, low grade fever, or any other anaphylaxis event. With no clear on whether or not the booster would be safe for her to take, she made the decision to take a booster at (privacy) on 15Oct2021 at 01:00 PM. It was reported that by 10 PM that night (15Oct2021) she once again had severe tremors, chills, aches, joint pain and 101.7 fever which lasted for three days followed by extreme fatigue (Oct2021). She was currently relieved that she was as protected as possible from COVID-19, but concerned that she will have to obtain a yearly booster shot for the disease. She asked if it was not safe for her to do so and if her reaction was abnormal. Booster dose due to high risk of frequent institutional or occupational exposure to coronavirus (and at risk of serious covid-19 complications): over 65. The patient took paracetamol (TYLENOL) oral for fever and aches on 08Feb2021, 12Feb2021, 15Oct2021 and 19Oct2021. No relevant test was reported. The outcome of the events was resolved on 19Oct2021 for "101.7 fever" and unknown for all other events.  Follow-up (11Nov2021): Follow-up attempts are completed. No further information is expected.; Sender's Comments: Linked Report(s) : US-PFIZER_INC-202101546711 same drug and patient, different event and drug dose;US-PFIZER INC-202101281664 same drug and patient, different event and drug dose