Yeast infection; This is a spontaneous report from a Pfizer-sponsored program. A contactable consumer (patient) reported that a 79-year-old female patient received the first dose of BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE; Lot Number and Expiration Date were not reported), via an unspecified route of administration in right arm, on 15Jan2021, at a single dose, for COVID-19 immunization. The patient's medical history included yeast infection, braces, and facial fillers. The patient's concomitant medications were not reported. The patient got the first dose of COVID-19 vaccine on 15Jan2021 and was asking if there is any problem for her taking yeast infection medication, fluconazole (DIFLUCAN) and antibiotics. On 18Jan2021, the patient came up with the yeast infection after the vaccine injection. The patient noticed that she had yeast infection because she had those before. The patient was asking if she can take fluconazole and if there would be any interactions. Also, her dental work was scheduled after the vaccine injections. The patient could not find information if there was a problem taking antibiotic after someone got the COVID-19 vaccine. The patient had to premedicate before she has her dental work done and wanted to know if there was a problem taking antibiotics (clindamycin or doxycycline). The patient was scheduled a dental procedure and was asking for information with potential interactions with antibiotics such as doxycycline and clindamycin. The patient read that some people had sound like some bad reactions to getting fillers done even 6 months prior to getting the COVID-19 shot. The patient was thinking about getting a filler done in the first part of Feb2021 but after reading that, she thought forget it - she was not going to do that because she read that people had reactions to fillers, like this one person had a filler done 6 months before she had a COVID-19 shot and she was not the only person there were some other people, that had a swelling around the mouth. The patient was referring to facial fillers, when people get fillers done on their face and they would have reactions around their mouth. The patient assumed that it was, were they had the fillers placed on face. The patient was referring to fillers such as JUVEDERM and RESTYLANE or BOTOX. The patient was asking if there had been reactions with vaccination if people had facial fillers because her daughter was getting BOTOX done. The patient was concerned about her daughter possibly getting BOTOX based on what she has read. The patient was getting ready to have fillers done but based on what she read she will wait - what concerned her that person had her fillers done 6 months prior to COVID-19 shot. The patient has read everything. The pages that they gave her at the hospital where she had the vaccine didn't have any information about taking fluconazole. The patient was just calling to see if she could take fluconazole. The patient has some that she can take from when she had a yeast infection before. The patient doesn't think the yeast infection has anything to do with the vaccine. The patient did not have any problems with the vaccine. The patient had not recovered from the event. The causality of the event was assessed as unrelated to the suspect vaccine product.  Information about lot number and expiration date for the suspect product will be requested in follow-up attempts.; Sender's Comments: Based on the available information, the event yeast infection is attributed to an intercurrent medical condition and assessed unrelated to  BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE).