Caller stated that she got her three shot, the booster shot two days ago.; Every time she breathes in it hurts; It also whistles inside when she breathes out / hurts when she inhales, she also started wheezing; When I breathe, it is shallow because it hurts / I cannot take a deep breath; it is right in the center of her chest only when she breathes in; Stated that when she takes in air it hurts and is uncomfortable; This is a spontaneous report received from a contactable reporter(s) (Consumer or other non HCP) from medical information team. The reporter is the patient.  A 49 year-old female patient received bnt162b2 (COMIRNATY), administration date 2021 (Batch/Lot number: unknown) as dose 3 (booster), single for covid-19 immunisation. Relevant medical history included: "kidney transplant" (unspecified if ongoing), notes: she had a kidney transplant a few years go. The patient's concomitant medications were not reported. Vaccination history included: Bnt162b2 (Dose 01), for COVID-19 immunization; Bnt162b2 (Dose 02), for COVID-19 immunization, reaction(s): "second dose: stated that she had discomfort"; Flu vaccine (she got the flu shot around second vaccine). The following information was reported: IMMUNISATION (non-serious) with onset 2021, outcome "unknown", described as "Caller stated that she got her three shot, the booster shot two days ago."; PAIN (non-serious) with onset 2021, outcome "unknown", described as "Every time she breathes in it hurts"; WHEEZING (non-serious) with onset 2021, outcome "unknown", described as "It also whistles inside when she breathes out / hurts when she inhales, she also started wheezing"; HYPOPNOEA (non-serious) with onset 2021, outcome "unknown", described as "When I breathe, it is shallow because it hurts / I cannot take a deep breath"; CHEST PAIN (non-serious) with onset 2021, outcome "unknown", described as "it is right in the center of her chest only when she breathes in"; DYSPNOEA (non-serious) with onset 2021, outcome "unknown", described as "Stated that when she takes in air it hurts and is uncomfortable".  Additional Information: other products and investigation assessment was not provided. The patient said she was "about to be 50 years old". The patient received her Comirnaty booster dose 2 days ago and that "every time she breathes in it hurts and it also whistles inside when she breathes out". The patient wanted to know if this was something she should be concerned about. The patient also asked if this was a side effect from the vaccine and if there was anything she should be taking for it. The patient stated she was not sick before she got the booster dose. She wanted to know if this was happening to other people since this was the third time she got Comirnaty and she was been fine until this one. The patient added she did not have fever. She also added that if this was a side effect then she will just wait for it to went away for a couple of days. The patient said "it hurts when she inhales, she also started wheezing", said "it hurts, it is painful. When I inhale, I cannot take a deep breath". When "I breathe, it is shallow because it hurts." The patient stated she had been doing really well. Before pandemic, she was about to go to work. Caller also added that "it is right in the center of her chest only when she breathes in". The patient also mentioned she was afraid to go to the hospital. The patient also said she did not think she could survive Covid-19. Spoken from attached document under Myocarditis and Pericarditis, mentioned this was not definite and referred to HCP. The patient stated that today it was worst. Wanted to know if this was something that she should be concerned about. Stated that "when she takes in air it hurts and is uncomfortable". Stated that had discomfort with the second one and it lasted a couple of days and was fine.  The lot number for bnt162b2 was not provided and will be requested during follow up.