I felt excessively slightly warm; weak; My blood pressure was down to 80 over 50; I felt as if I was dying; ache in my thighs; feeling faint; very mild temperature (99 to my average 97.6); experience pain in my right hand; nauseous; This spontaneous case was reported by a patient and describes the occurrence of FEELING HOT (I felt excessively slightly warm), ASTHENIA (weak), HYPOTENSION (My blood pressure was down to 80 over 50), FEELING ABNORMAL (I felt as if I was dying) and PAIN IN EXTREMITY (ache in my thighs) in a 62-year-old female patient who received mRNA-1273 BIVALENT .222 (MODERNA COVID-19 VACCINE, BIVALENT (ORIGINAL AND OMICRON BA.4/BA.5)) (batch no. AS7147B) for COVID-19 prophylaxis. The occurrence of additional non-serious events is detailed below.     No Medical History information was reported.    On 20-Sep-2022, the patient received fourth dose of mRNA-1273 BIVALENT .222 (MODERNA COVID-19 VACCINE, BIVALENT (ORIGINAL AND OMICRON BA.4/BA.5)) (Intramuscular) 1 dosage form. On 20-Sep-2022, the patient experienced FEELING HOT (I felt excessively slightly warm), ASTHENIA (weak), HYPOTENSION (My blood pressure was down to 80 over 50), FEELING ABNORMAL (I felt as if I was dying), PAIN IN EXTREMITY (ache in my thighs), DIZZINESS (feeling faint), PYREXIA (very mild temperature (99 to my average 97.6)), VACCINATION SITE PAIN (experience pain in my right hand) and NAUSEA (nauseous). The patient was treated with ELECTROLYTES NOS, GLUCOSE (PEDIALYTE [ELECTROLYTES NOS;GLUCOSE]) at an unspecified dose and frequency. On 22-Sep-2022, FEELING HOT (I felt excessively slightly warm), ASTHENIA (weak), HYPOTENSION (My blood pressure was down to 80 over 50), FEELING ABNORMAL (I felt as if I was dying), PAIN IN EXTREMITY (ache in my thighs), DIZZINESS (feeling faint), VACCINATION SITE PAIN (experience pain in my right hand) and NAUSEA (nauseous) had resolved. At the time of the report, PYREXIA (very mild temperature (99 to my average 97.6)) had resolved.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): In September 2022, Blood pressure measurement: 80 over 50. In September 2022, Body temperature: 99 to my average 97.6.     For mRNA-1273 BIVALENT .222 (MODERNA COVID-19 VACCINE, BIVALENT (ORIGINAL AND OMICRON BA.4/BA.5)) (Intramuscular), the reporter did not provide any causality assessments.   Concomitant products were not reported.  It was reported that vaccine was administered on patient right upper arm. By afternoon, patient began to experience pain in right hand and an ache in thighs. By that evening, had severe pain in right hand and could not put pinky to thumb without tears coming from eyes. Upon waking the next morning, the pain and ache had reduced. However, patient felt excessively slightly warm, very nauseous, weak, and when attempted to stand, nearly fainted. In fact, patient had to lay down numerous times before making it across to the other side of bed. Recognizing the symptoms of low blood pressure, patient took blood pressure on a calibrated in-home Omron gauge. Blood pressure was down to 80 over 50 and patient felt as if was going to dying. Immediately (well, as fast as the near fainting issue allowed too) treated the low blood pressure with Pedialite, water, and a high amount of Morton's iodized salt. Once the treatment took effect and raised BP, the nausea, weakness and feeling faint ceased and patient was able to go about day. By afternoon, the very mild temperature (99 to my average 97.6), the pain in hand, and the ache in thighs were either gone or relatively gone and was able to bring pinky to thumb again. It was unknown if the patient experienced any additional symptoms/events.