Extremely painful; unable to walk; Felt tired that same night / exhausted; lymph nodes inflamed and uncomfortable/left axilla inflammed / swollen lynph nodes in nect area; Left groin chaffing; neck discomfort; This spontaneous case was reported by a physician and describes the occurrence of GROIN PAIN (Left groin chaffing), MUSCULOSKELETAL DISCOMFORT (neck discomfort), PAIN (Extremely painful), GAIT INABILITY (unable to walk) and LYMPHADENOPATHY (lymph nodes inflamed and uncomfortable/left axilla inflammed / swollen lynph nodes in nect area) in a 64-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 011A21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     The patient's past medical history included Multiple fractures (Traumatic 20 ft. fall on 5/6/2019. Permanent soft tissue damage, 15 fractures including 3 in spine, shattered clavicle, brain injury, complete loss of use of R arm.) on 06-May-2019 and Brain injury on 06-May-2019. Concurrent medical conditions included Hypertension since 2000, Hypothyroidism (went from hypo to hyperthyroid in less than six months time.) since 1995, Drug allergy (Codeine.), Penicillin allergy, Drug allergy (Butalbital.), Drug allergy (Vicodin.), Drug allergy (Oxycodone.) and Drug allergy (Hydrocodone.). Concomitant products included RABEPRAZOLE SODIUM (ACIPHEX), AMLODIPINE, ALPRAZOLAM, LEVOTHYROXINE, BENAZEPRIL, HYDROMORPHONE and CYCLOBENZAPRINE for an unknown indication.    On 03-Mar-2021 at 4:00 AM, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 05-Mar-2021, the patient experienced GROIN PAIN (Left groin chaffing), MUSCULOSKELETAL DISCOMFORT (neck discomfort) and LYMPHADENOPATHY (lymph nodes inflamed and uncomfortable/left axilla inflammed / swollen lynph nodes in nect area). On an unknown date, the patient experienced PAIN (Extremely painful), GAIT INABILITY (unable to walk) and FATIGUE (Felt tired that same night / exhausted). On 15-Mar-2021, GROIN PAIN (Left groin chaffing), MUSCULOSKELETAL DISCOMFORT (neck discomfort), PAIN (Extremely painful), GAIT INABILITY (unable to walk), LYMPHADENOPATHY (lymph nodes inflamed and uncomfortable/left axilla inflammed / swollen lynph nodes in nect area) and FATIGUE (Felt tired that same night / exhausted) had resolved.        The action taken with mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) was unknown.   For mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular), the reporter considered GROIN PAIN (Left groin chaffing) and MUSCULOSKELETAL DISCOMFORT (neck discomfort) to be possibly related. No further causality assessments were provided for PAIN (Extremely painful), GAIT INABILITY (unable to walk), LYMPHADENOPATHY (lymph nodes inflamed and uncomfortable/left axilla inflammed / swollen lynph nodes in nect area) and FATIGUE (Felt tired that same night / exhausted).    Patient medical history includes limited use of right arm since 06 May 2019.  Patient lab data includes thyroid levels are too low.  No treatment information was reported.   This case was linked to MOD-2021-256770.   Most recent FOLLOW-UP information incorporated above includes: On 07-Jul-2021: Non-Significant Follow-Up document On 14-Jul-2021: Follow-up was received: Patient demographic details, medical history, allergic information, lab data, new events added, event outcome updated from unknown to recovered for all the events. Reporter causality was updated from not reported to possible