Then this past Tuesday (03-23-2021) I went to receive the 2nd Covid-19 Moderna Vaccine at 1:00pm. I felt fine and had no adverse after this vaccination until 8:30pm the same day. At this time I started to have sever  itching and within an hour the itching was over my entire body. It was a mixture of hives and regular pruritus/itching and areas of swelling throughout my body. This lasted all through the night into Wednesday, 03-24-21. Around the same time as the itching started Tuesday night, my Spinal joints, Hip joints, shoulder joints, knee joints, wrist and ankles became severely inflamed and very painful. On a scale of 1-10, 10 being the worst pain, at the highest I was at a 9.    On Wednesday, I went in to my Primary Care for the itching and the pain. My PCP is on vacation this week, so I saw his Colleague. Dr. visibly recognized the redness from the itching all over my body, along with the extreme pain to my joints and gave me a thorough examination. After his examination  he spoke to another physician who stepped in and also gave me an exam. Dr. advised the other Dr. and me of  his initial hesitancy  sending me home, wanting me to be observed overnight at the Hospital. After going to their Emergency Room. They gave me the choice but I truly thought it would go away over the course of the usual 24 hours post Vaccination; I also did not want to be exposed to any virus/sickness I might encounter/pick up in the Hospital due to my lowered immune system because of the rheumatoid arthritis injection Humira I take bi-monthly.. I explained that I was living with my mom, and our residence is 7 minutes from the Hospital, Emergency Room.) I assured both Physicians if it got worse, my mother would take me to the ER. So instead of going to Hospital, they prescribed a Hydrocortisone Cream of  2.5% for the itching, kept me on oral Benadryl and told me to stay hydrated. Also, Dr. said if it wasn?t better and/or worse Thursday(03/25/21)to come back in for re-evaluation. Along with the medications for itching, they prescribed a dose of pain medicine: Tylenol(APAP) #4 - or Acetaminophen with 60mg of Codeine.    Yesterday - Thursday(03-25-2021) I was no better, and had to go back in to the Clinic.  I was seen by Dr., who also believed this reaction to be based on the Humira along with my immune system naturally being lowered due to the AS and RA medication. Dr. examined me, as by yesterday my hands/fingers were hurting as well and itching was not any better. He prescribed Atarax (Hydroxyzine) 50mg Cap to be taken 3 times per day for the awful Pruritis, which has caused me to scratch so badly that I?ve had some bleeding from areas on my body, near the larger joints and spine. And also changed the Tylenol #4 to every 4 hours, basically more often for the pain associated.    Adding the Hydroxyzine for the itch along with the Hydrocortisone, pain medication and time since Tuesday?s final vaccine, has helped a bit. Today, Friday, I am feeling less itchy but still having quite a bit of joint pain, but less than Wednesday or Thursday of this week.  Because of the itching and joint/spine pain I received very little sleep until last evening when I was able to rest and not itch or toss and turn from pain. Hopefully on the mend.