intermittent nausea/she is not eating and she had to leave a patient's room because she almost threw up; Abdominal bloating; Epigastric pain; Indigestion; Chest pain; Perimenopause and through her into Menopause; Fever; hypertensive/hypertension; Tachycardia; she was not eating; This is a spontaneous report from a contactable healthcare professional (patient). This healthcare professional reported similar events for four patients. This is the first of four reports. A 50-year-old female patient received bnt162b2 (BNT162B2 reported as PFIZER-BIONTECH COVID-19 VACCINE), dose 2 via an unspecified route of administration in the right arm on 21Jan2021 [reported as afternoon] (Batch/Lot number was not reported) as 2nd dose, single dose for covid-19 immunisation. The patient received the first dose of bnt162b2 (BNT162B2 reported as PFIZER-BIONTECH COVID-19 VACCINE) at vaccination age of 50-year-old on 27Dec2020 in the left arm for covid-19 immunisation. The patient also previous had flu vaccine on an unspecified date for flu (she gets the flu vaccine every year). The patient's medical history and concomitant medications were not reported. The patient received the vaccine in a hospital. The patient reported that starting in Apr2021 and continuing on she began to have intermittent nausea, abdominal bloating, epigastric pain, indigestion and chest pain which is affecting her ability to live her normal life. She has reached to other people who have received the Pfizer Covid vaccine and they have reported similar side effects, that are unresolved. The patient reported that she has contacted CDC and was awaiting response. She was currently taking omeprazole 40 mg daily, just to get through the day. The reporter inquired what is in the vaccine is causing the GI to be affected and how do she treat it. She mentioned that she has 'no doubt' that the vaccine caused her symptoms. The reporter needed to know how and why the vaccine caused this so that she can continue to recommend the vaccine to her patients. She also inquired what symptoms are being seen in the area of reflux and gastritis status post vaccine, 2-3 months out. The patient reported that she started peri menopause and it through her into menopause (Apr2021). The patient stated that she presented tested with waves of intermittent nausea, abdominal bloating, epigastric pain, indigestion, and chest pain. She added that she was put on a PPI and she tried to do 20mg a day, but she has to do 20mg twice a day. The patient thought maybe she developed a gluten sensitivity and that reacts to wheat protein, so she tried to cut that out. She stated that she can't determine the process and wanted to know why it is occurring and/or if she needs to do preventative measures. She mentioned that there were other people experiencing exactly the same stuff. She added that she was not eating, and she had to leave a patient's room because she almost threw up. The patient also stated that she was having GI Issues, chest pain, fever and GI Symptoms on Apr2021, and she knew her daily check in would prompt her to get Covid tested. She also mentioned she was told her symptoms sounded like GI, H Pylori, or reflux, but they did not test. She was also hypertensive at that time (Apr2021). She mentioned that she is usually 110/70 (unknown date) but her systolic was 150 (Apr2021) and her pulse was 111 (Apr2021). She did have tachycardia and hypertension after the second vaccine, upwards of 114 bpm (Apr2021) and her resting heart rate did not go below 90 (2021). She added that started in Apr2021 but has resolved. Her EKG on Apr2021 done showed tall P Waves, and they said it could be related to cardiomyopathy or incidental. She reported that nothing showed on her cardiac markers, they were normal. She gets a yearly EKG with her hospital and previously they have always been normal. The patient mentioned the seriousness of this is medically significant, bordering disabling (serious with seriousness criteria of disabling/incapacitating and other medically important condition). Treatment included pantoprazole 40 mg a day, avoiding triggers and typical reflux treatment. She further added that her symptoms are better with the Pantoprazole, but they are still present. The outcome of the events hypertension, fever and tachycardia were recovered on an unspecified date in 2021 while the outcome of the events was not recovered.; Sender's Comments: Based on temporal association and profile of the product, the events were considered possibly related to suspect product bnt162b2 (BNT162B2 reported as PFIZER-BIONTECH COVID-19 VACCINE).,Linked Report(s) : US-PFIZER INC-2021623215 Same reporter/drug, similar events, different patients;US-PFIZER INC-2021623869 same reporter/drug/similar events, different patient;US-PFIZER INC-2021623328 same reporter/similar event, different patient