Chronic lymphocytic leukemia (CLL) cancer; basal cell carcinoma of the face; This spontaneous case was reported by a patient and describes the occurrence of CHRONIC LYMPHOCYTIC LEUKAEMIA (Chronic lymphocytic leukemia (CLL) cancer) and BASAL CELL CARCINOMA (basal cell carcinoma of the face) in a 69-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 013M20A, 0045211A and 041L20A) for COVID-19 prophylaxis.     Allergies of the patient were not provided. It was unknown if the patient ever had COVID + test or diagnosis.  Concurrent medical conditions included Immunocompromised.   On 13-Jan-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) .5 milliliter. On 09-Feb-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to .5 milliliter. On 01-Sep-2021, received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to .5 milliliter. In 2021, the patient experienced BASAL CELL CARCINOMA (basal cell carcinoma of the face) (seriousness criterion medically significant). On 15-Jul-2021,  after starting mRNA-1273 (Moderna COVID-19 Vaccine), the patient experienced CHRONIC LYMPHOCYTIC LEUKAEMIA (Chronic lymphocytic leukemia (CLL) cancer) (seriousness criterion medically significant). At the time of the report, CHRONIC LYMPHOCYTIC LEUKAEMIA (Chronic lymphocytic leukemia (CLL) cancer) had not resolved and BASAL CELL CARCINOMA (basal cell carcinoma of the face) outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On 18-Jun-2021, White blood cell count: elevated (High) elevated.         Concomitant medications were not provided by the reporter. It was reported that, patient was diagnosed with basal cell carcinoma of the face late in the year of 2021 (exact date was unknown).  Other vaccines given within 1 month prior to Moderna COVID-19 vaccine were unknown. Patient did not experience similar event of Chronic lymphocytic leukemia in the past.  It was unknown if the patient experienced similar even of Basal cell carcinoma (face) in the past. Treatment information was not provided.  Company comment: This spontaneous case concerns a 69 year old male patient with current condition of immunodeficiency who experienced the unexpected, serious (medically significant) event of Chronic lymphocytic leukemia and basal cell carcinoma. The event chronic lymphocytic leukemia occurred 5 months 6 days after receiving the second dose of mRNA1273, basal cell carcinoma started on an unspecified date post vaccination. Patient had a routine physical examination on 18-Jun-2021 which he was tested and revealed that his white blood cell count was elevated and has continued rising. Approximately a month later patient was diagnosed with Chronic lymphocytic leukemia (CLL) cancer by an oncologist. Later on an unspecified date he was further diagnosed with basal cell carcinoma of the face. Further details regarding the clinical course and treatment were not provided. The patient's underlying medical condition of immunodeficiency may be risk factor for the events in this case. Chronic lymphocytic leukemia may also be considered as predisposing factor for basal cell carcinoma. The benefit-risk relationship of mRNA-1273 vaccine is not affected by this report.   Reporter did not allow further contact; Sender's Comments: This spontaneous case concerns a 69 year old male patient with current condition of immunodeficiency who experienced the unexpected, serious (medically significant) event of Chronic lymphocytic leukemia and basal cell carcinoma. The event chronic lymphocytic leukemia occurred 5 months 6 days after receiving the second dose of mRNA1273, basal cell carcinoma started on an unspecified date post vaccination. Patient had a routine physical examination on 18-Jun-2021 which he was tested and revealed that his white blood cell count was elevated and has continued rising. Approximately a month later patient was diagnosed with Chronic lymphocytic leukemia (CLL) cancer by an oncologist. Later on an unspecified date he was further diagnosed with basal cell carcinoma of the face. Further details regarding the clinical course and treatment were not provided. The patient's underlying medical condition of immunodeficiency may be risk factor for the events in this case. Chronic lymphocytic leukemia may also be considered as predisposing factor for basal cell carcinoma. The benefit-risk relationship of mRNA-1273 vaccine is not affected by this report.