blockage arteries; give her steroids on 22Feb2021 for a week (prednisone pack) and when they stopped that she got another shot of steroids; who have had serum sickness; bad cold that won't go away; She very weak; malaise; serum sickness but it didn't turn out to be that / pretty sick now and they are trying to figure out what is going on; fatigue; This is a spontaneous report from a contactable consumer. A 87 Years non-pregnant female patient received second dose of bnt162b2 (PFIZER-BIONTECH COVID-19 VACCINE; Solution for injection; Lot Number: EL9269), intramuscular, administered in Arm Left on 10Feb2021 as SINGLE DOSE for covid-19 immunization and previously patient received bnt162b2 (PFIZER-BIONTECH COVID-19 VACCINE; Solution for injection; Lot Number: Unknown), dose 1 as SINGLE DOSE for covid-19 immunization. The patient's medical history included HTN, Cholesterol, Thyroid, statin sensitivity, borderline hypertension, stents. The patient's concomitant medications included ZETIA(EZETIMIBE), AMLODIPINE, METOPROLOL, THYROID, BIESTROGEN (ESTRADIOL, ESTRIOL). Prior to vaccination, the patient was not diagnosed with COVID-19. The patient did not receive any other vaccines within 4 weeks prior to the COVID vaccine. The patient received the second dose of the vaccine on 10Feb2021 and then a day or so after she developed what the physicians called serum sickness but it didn't turn out to be that. They started to give her steroids on 22Feb2021 for a week (prednisone pack) and she asked if the vaccine have less efficacy and when they stopped that she got another shot of steroids on 26Feb2021. It turned out she did not have the classic symptoms but have been quite sick. The pharmacist said you need to find out if the vaccine is still effective with all the steroids. She said she is in good health and is very athletic and she is pretty sick now and they are trying to figure out what is going on. She asked if her second vaccine was still effective with the steroids. Wants to know if steroid treatments will interfere with covid vaccine. Caller stated that she was fine after she received the first Pfizer Covid vaccine, but after receiving the second vaccine on 10Feb, she has felt like she's experiencing the onset of a bad cold that won't go away. She very weak and cannot do things that she normally does. Two weeks after her second vaccination, she was prescribed a methylprednisolone pack for a week and then she got a "big shot more" and then her doctor stopped for fear that had "played with her immune system". She's had her blood drawn and her lab values have all come back in normal range. Her doctor has tried everything he knows to do, but she cannot seem to pull out of it. Her second vaccination for Covid-19 was on 10Feb2021. Previous to that I was in good health, very active such as playing tennis and working out in the gym. she do, however, have borderline hypertension with six stents. Her blood pressure fluctuates 120's to the 140's. After the second shot was given she had a malaise which lasted for almost a month. When It first appeared she really felt as though she had the flu. Much the same symptoms. She had to Frequently rest even though we had to move from out home the next month. Her husband was a big help and she struggled to do her share. The patient health care provider contacted Pfizer to try and get some information as it was difficult to know how to treat this problem. There wasn't any solution so she just rode it out. Last week she finally started back to the gym. She had been walking several miles daily two weeks before that. Unrelated was a hospitalization for several days 31Mar2021 with a suspicion that she had a blockage In her arteries. A Cath procedure said everything had been running smoothly and her heart was beating correctly. So all those suspicious were ruled out. It was noted that she had made antibodies for Covid-19. She can't be more definite than saying she had flu like symptoms for about a month after the second shot. On an unspecified date, The patient experienced blockage arteries, give her steroids on 22Feb2021 for a week (prednisone pack) and when they stopped that she got another shot of steroids, who have had serum sickness, bad cold that won't go away, She very weak, malaise, On 11Feb2021 serum sickness but it didn't turn out to be that/pretty sick now and they are trying to figure out what is going, fatigue. The patient received treatment for adverse event (Medrol dose Pack, Decadron 6 mg IM x1 ). The clinical outcome of the events were unknown and outcome of the events bad cold that won't go away, serum sickness but it didn't turn out to be that pretty sick now and they are trying to figure out what is going, fatigue were Not recovered.