brucella IG M positive; low white blood cell count; AST increased; ALT increased; SAP increased; Elevated ESR; heart arrhythmia; atrial tachycardia; right cervical pain; purple discoloration of entire digit 4 of right foot; occipital nerve neuralgia (right); sciatic nerve pain (right); Elevated liver enzymes; Fever as high as 103; chronic fatigue; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP).  A 64 year-old female patient received bnt162b2 (BNT162B2), intramuscular, administered in arm left, administration date 11Oct2021 09:00 (Lot number: 30125BA) as dose 3 (booster), single for covid-19 immunisation. Relevant medical history included: "hypothyroidism", start date: 2016 (ongoing); "partial hysterectomy", start date: 1998 (ongoing); "left femur fx hemiarthroplasty", start date: 1987 (ongoing); "Acetabulum replaced left", start date: 2003 (ongoing). Concomitant medication(s) included: LEVOTHYROXINE taken for hypothyroidism, start date: 2016 (ongoing). Vaccination history included: Bnt162b2 (DOSE 1, SINGLE, Anatomical site of injection: left arm , route of administration: Intramuscular , batch lot no: EL3245), administration date: 21Jan2021, for COVID-19 Immunization; Bnt162b2 (DOSE 2, SINGLE, Anatomical site of injection: right arm , route of administration: Intramuscular , batch lot no: EL9269), administration date: 12Feb2021, for COVID-19 Immunization; Flu (Route: Intramuscular, Anatomical site of Injection: Right arm), administration date: 13Sep2021. The following information was reported: BRUCELLA TEST POSITIVE (hospitalization), outcome "unknown", described as "brucella IG M positive"; WHITE BLOOD CELL COUNT DECREASED (hospitalization), outcome "unknown", described as "low white blood cell count"; ASPARTATE AMINOTRANSFERASE INCREASED (hospitalization), outcome "unknown", described as "AST increased"; ALANINE AMINOTRANSFERASE INCREASED (hospitalization), outcome "unknown", described as "ALT increased"; BLOOD ALKALINE PHOSPHATASE INCREASED (hospitalization), outcome "unknown", described as "SAP increased"; RED BLOOD CELL SEDIMENTATION RATE INCREASED (hospitalization), outcome "unknown", described as "Elevated ESR"; PYREXIA (hospitalization) with onset 15Oct2021 15:00, outcome "recovered" (25Oct2021), described as "Fever as high as 103"; OCCIPITAL NEURALGIA (hospitalization) with onset 18Oct2021, outcome "recovering", described as "occipital nerve neuralgia (right)"; SCIATICA (hospitalization) with onset 18Oct2021, outcome "recovering", described as "sciatic nerve pain (right)"; HEPATIC ENZYME INCREASED (hospitalization) with onset 17Oct2021, outcome "not recovered", described as "Elevated liver enzymes"; ARRHYTHMIA (hospitalization), outcome "recovering", described as "heart arrhythmia"; ATRIAL TACHYCARDIA (hospitalization), outcome "unknown", described as "atrial tachycardia"; SKIN DISCOLOURATION (hospitalization) with onset 22Oct2021, outcome "not recovered", described as "purple discoloration of entire digit 4 of right foot"; NECK PAIN (hospitalization) with onset 27Oct2021, outcome "unknown", described as "right cervical pain"; FATIGUE (non-serious) with onset 11Oct2021, outcome "unknown", described as "chronic fatigue". The patient was hospitalized for brucella test positive, white blood cell count decreased, aspartate aminotransferase increased, alanine aminotransferase increased, blood alkaline phosphatase increased, red blood cell sedimentation rate increased, pyrexia, occipital neuralgia, sciatica, hepatic enzyme increased, arrhythmia, atrial tachycardia, skin discolouration, neck pain (hospitalization duration: 3 day(s)). The events "brucella ig m positive", "low white blood cell count", "occipital nerve neuralgia (right)", "sciatic nerve pain (right)", "right cervical pain" were evaluated at the emergency room visit. The events "ast increased", "alt increased", "sap increased", "elevated esr", "fever as high as 103" and "elevated liver enzymes" were evaluated at the physician office visit and emergency room visit. The patient underwent the following laboratory tests and procedures: alanine aminotransferase increased: (16Oct2021) elevated; antibody test: (16Oct2021) unknown results; (16Oct2021) unknown results; aspartate aminotransferase increased: (16Oct2021) elevated; bartonella test: (16Oct2021) unknown results; blood alkaline phosphatase increased: (16Oct2021) elevated; blood culture: (16Oct2021) negative, notes: 3 times; blood immunoglobulin g: (16Oct2021) negative; blood lactic acid: (16Oct2021) unknown results; body temperature: (16Oct2021) 103 Fahrenheit; brucella test: (16Oct2021) positive; computerised tomogram: (16Oct2021) normal; cytomegalovirus test: (16Oct2021) unknown results; epstein-barr virus test: (16Oct2021) unknown results; full blood count: (16Oct2021) low; hepatitis viral test: (16Oct2021) unknown results; influenza virus test: (16Oct2021) unknown results; investigation: (16Oct2021) positive; (16Oct2021) unknown results; leptospira test: (16Oct2021) unknown results; liver function test: (16Oct2021) elevated; magnetic resonance imaging: (unspecified date) normal; (16Oct2021) normal; metabolic function test: (16Oct2021) unknown results; respiratory syncytial virus test: (16Oct2021) unknown results; sars-cov-2 test: (16Oct2021) negative; (16Oct2021) negative. Therapeutic measures were taken as a result of occipital neuralgia, sciatica, arrhythmia, atrial tachycardia. Therapeutic measures were not taken as a result of hepatic enzyme increased. No follow-up attempts are possible. No further information is expected.