blood blisters on palms and bottom of his feet/spread to his elbowsand base of his spine/If he applies pressure anywhere in hands or feet, a blood blister would appear/blisters in hands and feet; when there is pressure or friction, lesions presents; concluded that he had vascular problems/it is not a skin problem, but a vascular problem; the blood vessel under his skin is being attacked by his immune system; he is now hyper allergic to things he has never been allergic to anything other than penicillin/extreme allergic reaction that he's never experienced before; he keeps getting hives/hives on his body; ended up in the ER in 18JUL2021 for an adverse reaction to a bug bite/bug bite that ended in ER; his face swelled up and he had hives; this is causing the patient physical distress; this is causing the patient mental distress; This spontaneous case was reported by a consumer and describes the occurrence of BLOOD BLISTER (blood blisters on palms and bottom of his feet/spread to his elbow sand base of his spine/If he applies pressure anywhere in hands or feet, a blood blister would appear/blisters in hands and feet), SKIN LESION (when there is pressure or friction, lesions presents), ANGIOPATHY (concluded that he had vascular problems/it is not a skin problem, but a vascular problem), IMMUNE SYSTEM DISORDER (the blood vessel under his skin is being attacked by his immune system) and ALLERGY TO VACCINE (he is now hyper allergic to things he has never been allergic to anything other than penicillin/extreme allergic reaction that he's never experienced before) in a 53-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 016D21A and 029A21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     The patient's past medical history included Biopsy (Patient also started visiting the dermatologist who performed a biopsy 2 weeks ago and concluded that he had vascular problems and the blood vessel under his skin is being attacked by his immune system). Concurrent medical conditions included Penicillin allergy.   On 10-Mar-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 06-Apr-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On an unknown date, the patient experienced BLOOD BLISTER (blood blisters on palms and bottom of his feet/spread to his elbowsand base of his spine/If he applies pressure anywhere in hands or feet, a blood blister would appear/blisters in hands and feet), SKIN LESION (when there is pressure or friction, lesions presents), ANGIOPATHY (concluded that he had vascular problems/it is not a skin problem, but a vascular problem), IMMUNE SYSTEM DISORDER (the blood vessel under his skin is being attacked by his immune system), ALLERGY TO VACCINE (he is now hyper allergic to things he has never been allergic to anything other than penicillin/extreme allergic reaction that he's never experienced before), URTICARIA (he keeps getting hives/hives on his body), ARTHROPOD BITE (ended up in the ER in 18JUL2021 for an adverse reaction to a bug bite/bug bite that ended in ER), SWELLING FACE (his face swelled up and he had hives), GENERAL PHYSICAL HEALTH DETERIORATION (this is causing the patient physical distress) and EMOTIONAL DISTRESS (this is causing the patient mental distress). The patient was treated with CEFALEXIN (KEFLEX [CEFALEXIN]) at an unspecified dose and frequency. At the time of the report, BLOOD BLISTER (blood blisters on palms and bottom of his feet/spread to his elbowsand base of his spine/If he applies pressure anywhere in hands or feet, a blood blister would appear/blisters in hands and feet), SKIN LESION (when there is pressure or friction, lesions presents), ANGIOPATHY (concluded that he had vascular problems/it is not a skin problem, but a vascular problem), IMMUNE SYSTEM DISORDER (the blood vessel under his skin is being attacked by his immune system), ALLERGY TO VACCINE (he is now hyper allergic to things he has never been allergic to anything other than penicillin/extreme allergic reaction that he's never experienced before), URTICARIA (he keeps getting hives/hives on his body), ARTHROPOD BITE (ended up in the ER in 18JUL2021 for an adverse reaction to a bug bite/bug bite that ended in ER), SWELLING FACE (his face swelled up and he had hives), GENERAL PHYSICAL HEALTH DETERIORATION (this is causing the patient physical distress) and EMOTIONAL DISTRESS (this is causing the patient mental distress) outcome was unknown.            No concomitant medication was provided.  Steroids were given as treatment medication   Most recent FOLLOW-UP information incorporated above includes: On 12-Aug-2021: No new Information was provided On 20-Aug-2021: Follow-up contains non-significant information