Sweats; Very swollen arm; Muscle loss; Cant sleep at night; Lump in the front part of my breast; My arm hurts/ Arm is still killing me; Burning in arm; Can not move it; Skin is hanging; Body aches/ hurts bad/ sore; Enlarged lymph node; fever; it's getting to be tiresome; chills; arm is still killing me (injection site); Stiff shoulder; Sore arm/ Can not lift arm all the way up; Swollen lymph nodes; Sore shoulder; This spontaneous case was reported by a health care professional and describes the occurrence of MUSCULOSKELETAL STIFFNESS (Stiff shoulder), PAIN IN EXTREMITY (Sore arm/ Can not lift arm all the way up), HYPERHIDROSIS (Sweats), PERIPHERAL SWELLING (Very swollen arm) and MUSCLE ATROPHY (Muscle loss) in a 51-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 017821A and 030A21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     Concomitant products included VITAMIN D NOS, LEVOTHYROXINE from 01-Jan-2005 to an unknown date, LISINOPRIL from 01-Jan-2005 to an unknown date and MULTIVITAMIN [VITAMINS NOS] for an unknown indication.   On 29-Mar-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 26-Apr-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 26-Apr-2021, the patient experienced MUSCULOSKELETAL STIFFNESS (Stiff shoulder), PAIN IN EXTREMITY (Sore arm/ Can not lift arm all the way up), LYMPHADENOPATHY (Swollen lymph nodes) and ARTHRALGIA (Sore shoulder). On an unknown date, the patient experienced HYPERHIDROSIS (Sweats), PERIPHERAL SWELLING (Very swollen arm), MUSCLE ATROPHY (Muscle loss), INSOMNIA (Cant sleep at night), BREAST MASS (Lump in the front part of my breast), PAIN IN EXTREMITY (My arm hurts/ Arm is still killing me), BURNING SENSATION (Burning in arm), INJECTED LIMB MOBILITY DECREASED (Can not move it), SKIN LAXITY (Skin is hanging), MYALGIA (Body aches/ hurts bad/ sore), LYMPHADENOPATHY (Enlarged lymph node), PYREXIA (fever), FATIGUE (it's getting to be tiresome), CHILLS (chills) and VACCINATION SITE PAIN (arm is still killing me (injection site)). At the time of the report, MUSCULOSKELETAL STIFFNESS (Stiff shoulder), PAIN IN EXTREMITY (Sore arm/ Can not lift arm all the way up), HYPERHIDROSIS (Sweats), PERIPHERAL SWELLING (Very swollen arm), PAIN IN EXTREMITY (My arm hurts/ Arm is still killing me), LYMPHADENOPATHY (Swollen lymph nodes), ARTHRALGIA (Sore shoulder), PYREXIA (fever), FATIGUE (it's getting to be tiresome) and CHILLS (chills) had not resolved and MUSCLE ATROPHY (Muscle loss), INSOMNIA (Cant sleep at night), BREAST MASS (Lump in the front part of my breast), BURNING SENSATION (Burning in arm), INJECTED LIMB MOBILITY DECREASED (Can not move it), SKIN LAXITY (Skin is hanging), MYALGIA (Body aches/ hurts bad/ sore), LYMPHADENOPATHY (Enlarged lymph node) and VACCINATION SITE PAIN (arm is still killing me (injection site)) outcome was unknown.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On an unknown date, Mammogram: abnormal (abnormal) Found an enlarged lymph node.     For mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown), the reporter considered MUSCULOSKELETAL STIFFNESS (Stiff shoulder), PAIN IN EXTREMITY (Sore arm/ Can not lift arm all the way up), LYMPHADENOPATHY (Swollen lymph nodes) and ARTHRALGIA (Sore shoulder) to be possibly related. No further causality assessments were provided for HYPERHIDROSIS (Sweats), PERIPHERAL SWELLING (Very swollen arm), MUSCLE ATROPHY (Muscle loss), INSOMNIA (Cant sleep at night), BREAST MASS (Lump in the front part of my breast), PAIN IN EXTREMITY (My arm hurts/ Arm is still killing me), BURNING SENSATION (Burning in arm), INJECTED LIMB MOBILITY DECREASED (Can not move it), SKIN LAXITY (Skin is hanging), MYALGIA (Body aches/ hurts bad/ sore), LYMPHADENOPATHY (Enlarged lymph node), PYREXIA (fever), FATIGUE (it's getting to be tiresome), CHILLS (chills) and VACCINATION SITE PAIN (arm is still killing me (injection site)).    No treatment medication was taken by the patient.  The patient had a lump in the front part of breast left side. The physician wants the patient to visit a breast specialist.  On an unknown date, the patient had ultrasound. The patient had muscle loss.   This case was linked to MOD-2021-264071 (Patient Link).   Most recent FOLLOW-UP information incorporated above includes: On 22-Jul-2021: Follow up received and contains no new information. On 15-Aug-2021: Follow up information received on 16-Aug-2021: new events were added