Upset stomach; Diarrhea; Itchy hands and feet; This is a spontaneous report received from contactable reporter(s) (Other HCP). The reporter is the patient.  35 year-old female patient received bnt162b2 (BNT162B2), administered in deltoid right, administration date 31Dec2020 (Lot number: EL0140) at the age of 35 years as dose 1, single for covid-19 immunisation. The patient had no relevant medical history. There were no concomitant medications. The following information was reported: ABDOMINAL DISCOMFORT (non-serious) with onset Jan2021, outcome "not recovered", described as "Upset stomach"; DIARRHOEA (non-serious) with onset Jan2021, outcome "not recovered", described as "Diarrhea"; PRURITUS (non-serious) with onset Jan2021, outcome "not recovered", described as "Itchy hands and feet". The events "upset stomach", "diarrhea" and "itchy hands and feet" were evaluated at the physician office visit. Relevant laboratory tests and procedures are available in the appropriate section. Therapeutic measures were taken as a result of abdominal discomfort, diarrhoea, pruritus.  Additional information: Concomitant Medications: No, she saw an allergist immunologist they did testing for food, environmental, PEG polyethylene Glycol testing, they event tested for autoimmune disorders but everything was normal. Investigation - No, just the excessive labs and abdominal scans which were all normal. Only tests she had are from the allergist and ER. She has no Allergies. Caller clarified that after the first dose on 31Dec2020, 2 days after she experienced itchy hands and feet and upset stomach, but when she got the second dose that's when it really hit her. on 23JAN2021, this was the same night was called, she went to the ER, she is in a smaller community, and when she went to the ER the hospital was full, and so they treated her outside till she got to baseline and the swelling went down with steroids, Epi pen, and Benadryl. Anaphylaxis Outcome: It randomly happens every few months or multiple times in a month, there is no pattern. She initially thought it was improving but then in Jun2021 she had an episode that needed Epinephrine 3 times before she got relief. Itching: It happens during each reaction and varies with each episode, initially it was like a clue that the reaction is coming, so then she would dose with Benadryl, get the Epipen ready, and get close to an ER facility. Seriousness Criteria: Her entire body system is going into that. Caller selects Hospitalization but then clarifies that It doesn't get to the point of being admitted into the hospital. Upset stomach: It happened after the first dose and happens in every episode. Diarrhea: Happens with with each episode. First Dose Lot: Caller states that it is difficult to read since it is handwritten. She provides Lot EL0140. Caller states that she is guessing that both vaccines were administered into the right deltoid. EpiPen: She has used 20 or more EpiPen's, she cant give all the Lots. She only has EpiPen's that are unused, they are not used at all. All previous EpiPen's that were used have been discarded and she has no Lot. Steroid name she thinks is Prednisone, she is not sure, or the generic for it. She has no Lot as it has all been Discarded. They give it to her with each episode. Benadryl: She uses it during an episode but she doesn't have it with her to provide Lot.  Description of complaint: Itching: It happens during each reaction and varies with each episode, initially it was like a clue that the reaction is coming, so then she would dose with Benadryl, get the Epipen ready, and get close to an ER facility. EpiPen: She has used 20 or more EpiPen's, she cant give all the Lots. She only has EpiPen's that are unused, they are not used at all. All previous EpiPen's that were used have been discarded and she has no Lot. Steroid name she thinks is Prednisone, she is not sure, or the generic for it. She has no Lot as it has all been Discarded. They give it to her with each episode.  Follow-up attempts are completed. No further information is expected.