horrible localized allergic reaction: Ping- Pong size area on arm, raised, Red, and itching intensely/the injection site was very itchy; horrible localized allergic reaction: Ping- Pong size area on arm, raised, Red, and itching intensely/the injection site was very red/the red area had increased to the size of her hand; horrible localized allergic reaction: Ping- Pong size area on arm, raised, Red, and itching intensely; This spontaneous case was reported by a nurse and describes the occurrence of VACCINATION SITE PRURITUS (horrible localized allergic reaction: Ping- Pong size area on arm, raised, Red, and itching intensely/the injection site was very itchy), VACCINATION SITE ERYTHEMA (horrible localized allergic reaction: Ping- Pong size area on arm, raised, Red, and itching intensely/the injection site was very red/the red area had increased to the size of her hand) and VACCINATION SITE SWELLING (horrible localized allergic reaction: Ping- Pong size area on arm, raised, Red, and itching intensely) in a 69-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 004F21A, 046A21A and 023M20A) for COVID-19 vaccination.     No medical history information was reported.  Concomitant products included INFLUENZA VACCINE and TETANUS VACCINE for an unknown indication.   On 25-Feb-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 25-Mar-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 16-Nov-2021, received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 16-Nov-2021, the patient experienced VACCINATION SITE PRURITUS (horrible localized allergic reaction: Ping- Pong size area on arm, raised, Red, and itching intensely/the injection site was very itchy), VACCINATION SITE ERYTHEMA (horrible localized allergic reaction: Ping- Pong size area on arm, raised, Red, and itching intensely/the injection site was very red/the red area had increased to the size of her hand) and VACCINATION SITE SWELLING (horrible localized allergic reaction: Ping- Pong size area on arm, raised, Red, and itching intensely). The patient was treated with HYDROCORTISON [HYDROCORTISONE] on 16-Nov-2021 for Adverse event, at an unspecified dose and frequency and CORTISONE for Adverse event, at an unspecified dose and frequency. On 21-Nov-2021, VACCINATION SITE PRURITUS (horrible localized allergic reaction: Ping- Pong size area on arm, raised, Red, and itching intensely/the injection site was very itchy), VACCINATION SITE ERYTHEMA (horrible localized allergic reaction: Ping- Pong size area on arm, raised, Red, and itching intensely/the injection site was very red/the red area had increased to the size of her hand) and VACCINATION SITE SWELLING (horrible localized allergic reaction: Ping- Pong size area on arm, raised, Red, and itching intensely) had resolved.        For mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown), the reporter did not provide any causality assessments.   The patient received the booster dose around 1 pm. By 5 pm after receiving the booster shot, the patient had adverse reactions. horrible localized allergic reaction: Ping- Pong size area on arm, raised, Red, and itching intensely. The patient used OTC Hydrocortisone cream 1% on it.  On 17-Nov-2021, the injection site was not as raised as the previous day. So, the patient called the doctor's office. The doctor prescribed Cortisone Cream 2% and it helped. In 4-5 days after using the Cortisone 2% the localized reaction went away.  As of, 10-Dec-2021 all symptoms of the patient were resolved, and the patient was only concerned about any future COVID-19 vaccines.   This case was linked to MOD-2021-408548 (Patient Link).