Itchy Red Hives appeared on the Trunk ,stomach, back,  legs and arms; Itchy Red Hives appeared on the Trunk ,stomach, back,  legs and arms; Itchy Red Hives appeared on the Trunk ,stomach, back,  legs and arms; Sore Left Leg; Tingling Left leg; Back of her left leg burns; Weakness on the left hand/lazy left fingers; Cold Left Leg; Swelled up (left side of face and lip); Feels cold all the time/freezing; Chills; swelling on the left side of face/left side of face swelled up; Sore Left Arm (Injection Site); This spontaneous case was reported by a consumer and describes the occurrence of SWELLING FACE (swelling on the left side of face/left side of face swelled up), LIP SWELLING (Swelled up (left side of face and lip)), FEELING COLD (Feels cold all the time/freezing), URTICARIA (Itchy Red Hives appeared on the Trunk ,stomach, back,  legs and arms) and PRURITUS (Itchy Red Hives appeared on the Trunk ,stomach, back,  legs and arms) in a 60-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch no. 040C21A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     The patient's past medical history included Thyroid cancer and Thyroidectomy (Thyroids were removed). Concomitant products included LEVOTHYROXINE SODIUM (LEVOTHYROXIN) for an unknown indication.    On 25-Jul-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 25-Jul-2021, the patient experienced SWELLING FACE (swelling on the left side of face/left side of face swelled up) and VACCINATION SITE PAIN (Sore Left Arm (Injection Site)). On 26-Jul-2021, the patient experienced LIP SWELLING (Swelled up (left side of face and lip)), FEELING COLD (Feels cold all the time/freezing) and CHILLS (Chills). On 27-Jul-2021, the patient experienced URTICARIA (Itchy Red Hives appeared on the Trunk ,stomach, back,  legs and arms), PRURITUS (Itchy Red Hives appeared on the Trunk ,stomach, back,  legs and arms), ERYTHEMA (Itchy Red Hives appeared on the Trunk ,stomach, back,  legs and arms), PAIN IN EXTREMITY (Sore Left Leg), PARAESTHESIA (Tingling Left leg), BURNING SENSATION (Back of her left leg burns), MUSCULAR WEAKNESS (Weakness on the left hand/lazy left fingers) and PERIPHERAL COLDNESS (Cold Left Leg). The patient was treated with DIPHENHYDRAMINE HYDROCHLORIDE (BENADRYL [DIPHENHYDRAMINE HYDROCHLORIDE]) for Lip swelling and Swelling of face, at an unspecified dose and frequency. At the time of the report, SWELLING FACE (swelling on the left side of face/left side of face swelled up), LIP SWELLING (Swelled up (left side of face and lip)), FEELING COLD (Feels cold all the time/freezing), URTICARIA (Itchy Red Hives appeared on the Trunk ,stomach, back,  legs and arms), PRURITUS (Itchy Red Hives appeared on the Trunk ,stomach, back,  legs and arms), ERYTHEMA (Itchy Red Hives appeared on the Trunk ,stomach, back,  legs and arms), PAIN IN EXTREMITY (Sore Left Leg), PARAESTHESIA (Tingling Left leg), BURNING SENSATION (Back of her left leg burns), MUSCULAR WEAKNESS (Weakness on the left hand/lazy left fingers), PERIPHERAL COLDNESS (Cold Left Leg), VACCINATION SITE PAIN (Sore Left Arm (Injection Site)) and CHILLS (Chills) outcome was unknown.        The action taken with mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) was unknown.       Most recent FOLLOW-UP information incorporated above includes: On 01-Oct-2021: Follow up received is non significant.