Stomach pains; No bowel function; Constipation; Energy and speaking voice reduced; Energy and speaking voice reduced; cold; Sore throat (on right side mostly); Lung partial blockade; expectorating significant amounts of lung and sinus debris, some clear, some yellowish in color.; complete sinus blockage (right side mostly); This spontaneous case was reported by a patient and describes the occurrence of NASOPHARYNGITIS (cold), OROPHARYNGEAL PAIN (Sore throat (on right side mostly)), OBSTRUCTIVE AIRWAYS DISORDER (Lung partial blockade), PRODUCTIVE COUGH (expectorating significant amounts of lung and sinus debris, some clear, some yellowish in color.) and SINONASAL OBSTRUCTION (complete sinus blockage (right side mostly)) in an elderly male patient who received mRNA-1273 BIVALENT .222 (MODERNA COVID-19 VACCINE, BIVALENT (ORIGINAL AND OMICRON BA.4/BA.5)) for COVID-19 prophylaxis. The occurrence of additional non-serious events is detailed below.     From 1985 - 2011, successfully treated most arthritis flares with natural method (dietary and lifestyle adjustments) Patient's medical history included in 2020, approximately 3 episodes of cortisone injections into left knee after fluid drain, latest episode March 2021, drained 90cc fluid Out Of knee, then cortisone shot, damaged left kidney.  The patient's past medical history included Combined tibia-fibula fracture ((4 places) in right knee, treated with casting and setting) in 1972, Staphylococcal infection (of left leg, concurrent with Hepatitis A.) in 1976, Hepatitis A in 1976, Psoriatic arthritis (due to having both generalized arthritis symptoms and psoriasis) in 1977, Gout (Gout episodes begin; sometimes managed with Co crys but often just with natural methods (celery seed, tart cherry, dietary adjustments).) in 2008, Infection (serious infection followed one week later after TKR. Keflex for treatment.) in March 2017, Cardiac arrhythmia (In Aug - Nov 2020, episodes of cardiac arrhythmia) in 2020, Premature atrial contraction in 2020, Chronic sinusitis, Nasal polyps, Constipation chronic, Bacterial pneumonia, unspecified in 1978, Total knee replacement (right total knee replacement) in March 2017, Surgery (kidney/ureter surgery to repair blocked left ureter) in 1980, Surgery (nasal polyp) in 2009 and Back surgery (for blown disc (1.4/1.5)) in March 2010. Previously administered products included for Infection: keflex in March 2017; for Psoriatic arthritis: Feldene and Indocin; for Obstruction lung disease: albuterol (Abuterol doses administered by nebulizer); for Product used for unknown indication: Cortisone (Nov 2014 - Jan 2017 and cortisone shots in right knee at intervals varying from 10-15 months). Past adverse reactions to the above products included No adverse reaction with Cortisone, Feldene, Indocin, albuterol and keflex. Concurrent medical conditions included Lyme's disease (Antibiotics not prescribed at this time, and it has flared every decade or so, including possibly in 2014.) in 1985, Arthritis flare up (increasing in frequency and severity beginning at this time.) since 2012, Asthma, Food allergy, Environmental allergy and Type 2 diabetes mellitus (managed with diet modification and exercise). Concomitant products included ALBUTEROL SULFATE for Asthma, TRIAMCINOLONE ACETONIDE for Psoriasis flare-up, PREDNISONE ACETATE, SALBUTAMOL (ALBUTEROL HFA), SILDENAFIL CITRATE (SILDENAFIL ABC), COLECALCIFEROL (VITAMIN D3 1000), VITAMIN B COMPLEX (VITAMIN B CO), VITAMIN A NOS, ZYFLAMEND WHOLE BODY, APIUM GRAVEOLENS SEED, BROMELAINS, CURCUMA LONGA ROOT, POTASSIUM CITRATE, PRUNUS SEROTINA FRUIT (GO OUT PLEX), PROBIOTICS NOS, SENNA ACUTIFOLIA, RHAMNUS PURSHIANA BARK (CASCARA SAGRADA [RHAMNUS PURSHIANA BARK]), ACETYLSALICYLIC ACID (CARDIOTON R), THIOCTIC ACID (ALPHA LIPOIC), NATTOKINASE, OLEA EUROPAEA OIL, PHYTOSTEROLS NOS, UBIDECARENONE (NATTOKINASE PLUS Q10), CRATAEGUS SPP. FRUIT (HAWTHORNE BERRY), MAGNESIUM CITRATE (MAGNESIUM CITRATE FORTE), LIPASE and CELERY SEED EXTRACT for an unknown indication.    In September 2022, the patient received fifth dose of mRNA-1273 BIVALENT .222 (MODERNA COVID-19 VACCINE, BIVALENT (ORIGINAL AND OMICRON BA.4/BA.5)) (unknown route) 50 milliliter. In 2022, the patient experienced NASOPHARYNGITIS (cold), OROPHARYNGEAL PAIN (Sore throat (on right side mostly)), OBSTRUCTIVE AIRWAYS DISORDER (Lung partial blockade), PRODUCTIVE COUGH (expectorating significant amounts of lung and sinus debris, some clear, some yellowish in color.), SINONASAL OBSTRUCTION (complete sinus blockage (right side mostly)), ASTHENIA (Energy and speaking voice reduced) and DYSPHONIA (Energy and speaking voice reduced). In September 2022, the patient experienced ABDOMINAL PAIN UPPER (Stomach pains), FUNCTIONAL GASTROINTESTINAL DISORDER (No bowel function) and CONSTIPATION (Constipation). At the time of the report, NASOPHARYNGITIS (cold), OROPHARYNGEAL PAIN (Sore throat (on right side mostly)), OBSTRUCTIVE AIRWAYS DISORDER (Lung partial blockade), PRODUCTIVE COUGH (expectorating significant amounts of lung and sinus debris, some clear, some yellowish in color.) and SINONASAL OBSTRUCTION (complete sinus blockage (right side mostly)) had not resolved, ABDOMINAL PAIN UPPER (Stomach pains), ASTHENIA (Energy and speaking voice reduced) and DYSPHONIA (Energy and speaking voice reduced) outcome was unknown and FUNCTIONAL GASTROINTESTINAL DISORDER (No bowel function) and CONSTIPATION (Constipation) was resolving.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): In November 2016, Exercise electrocardiogram: abnormal both knees, left especially bad. On an unknown date, Glomerular filtration rate: low, sometimes mid- forties, currently 46.     For mRNA-1273 BIVALENT .222 (MODERNA COVID-19 VACCINE, BIVALENT (ORIGINAL AND OMICRON BA.4/BA.5)) (Unknown), the reporter did not provide any causality assessments.   Patient's concomitant medications included aloe vera juice  kidney tonic.  Patient received first dose of Moderna vaccine 100 ml on 25-Feb-2021 at 11:00 AM on right arm with batch lot number 031M20A. Patient received second dose of Moderna vaccine 100 ml on 02-Apr-2021 at 11:00 AM on left arm with batch lot number 0312A21A. Patient received third dose of Moderna vaccine 100 ml on 30-Aug-2021 at 11:00 AM on left arm with batch lot number 039A21A. Patient received fourth dose of Moderna vaccine 100 ml on 27-Jan-2022 on right arm with batch lot number 007J21-214.  The patient had never been diagnosed with/tested positive for COVID-19. The night following the booster shot, the patient experienced stomach pains, no bowel function after administering 3 OTC constipation relief drugs (unspecified). Finally, after multiple enema procedures bowel blockage began to relent. After several days of increasingly better health a severe cold began. Symptoms included extreme sore throat on right side mostly, complete sinus blockage right side mostly requiring multiple mechanical flushes, lung partial blockage requiring multiple. Albuterol doses administered by nebulizer. This event continued 84 hours followed by gradual but incomplete improvement. At the time of this report, the patient was still congested, still minor sore throat, still expectorating significant amounts of lung and sinus debris, some clear, some yellowish in color. Energy and speaking voice reduced. Finally sleeping a bit better. Patient stated that this was the worst cold the patient had experienced since suffering bacterial pneumonia in 1978.   This case was linked to MOD-2021-032238, MOD-2021-651551, MOD-2022-651522, MOD-2022-651506 (Patient Link).