The spots on the patient's arm are swollen, injection area  and left shoulder  all extremely iitchy swelling and peeling; THe spots got worse, approximately 24 or 25 spots around his knees, arms, back and hip,Red spots the size of quarters on sides of knees also on ankles and wrists,; itchy; redness; hives; hypersensitivity reaction; This case was initially received via an unknown source (no reference has been entered for a health authority or license partner) on 29-Jul-2021. The most recent information was received on 09-Aug-2021 and was forwarded to Moderna on 09-Aug-2021.    This spontaneous case was reported by a patient family member or friend and describes the occurrence of PERIPHERAL SWELLING (The spots on the patient's arm are swollen, injection area  and left shoulder  all extremely iitchy swelling and peeling), RASH (THe spots got worse, approximately 24 or 25 spots around his knees, arms, back and hip,Red spots the size of quarters on sides of knees also on ankles and wrists,), HYPERSENSITIVITY (hypersensitivity reaction), PRURITUS (itchy) and ERYTHEMA (redness) in a 66-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 013A21A and 013M20A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     The patient's past medical history included Heart disease congenital in 2010 and Blood pressure high in 2010. Concomitant products included IRBESARTAN, HYDRALAZINE, ROSUVASTATIN, AMLODIPINE, CARVEDILOL and ACETYLSALICYLIC ACID (BABY ASPIRIN) for an unknown indication.   On 04-Feb-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) 1 dosage form. On 04-Mar-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to 1 dosage form. On 25-Feb-2021, the patient experienced HYPERSENSITIVITY (hypersensitivity reaction). On an unknown date, the patient experienced PERIPHERAL SWELLING (The spots on the patient's arm are swollen, injection area  and left shoulder  all extremely iitchy swelling and peeling), RASH (THe spots got worse, approximately 24 or 25 spots around his knees, arms, back and hip,Red spots the size of quarters on sides of knees also on ankles and wrists,), PRURITUS (itchy), ERYTHEMA (redness) and URTICARIA (hives). The patient was treated with DIPHENHYDRAMINE HYDROCHLORIDE (BENADRYL [DIPHENHYDRAMINE HYDROCHLORIDE]) for Adverse event, at an unspecified dose and frequency; CLOTRIMAZOLE (LOTRIMIN [CLOTRIMAZOLE]) for Antifungal treatment, at an unspecified dose and frequency; CORTISONE for Adverse event, at an unspecified dose and frequency; BENZOCAINE, CALAMINE (IVAREST [BENZOCAINE;CALAMINE]) for Adverse event, at an unspecified dose and frequency; TRIAMCINOLONE for Adverse event, at an unspecified dose and frequency and PRAMOCAINE HYDROCHLORIDE, ZINC ACETATE (CALADRYL CLEAR) for Antifungal treatment, at an unspecified dose and frequency. At the time of the report, PERIPHERAL SWELLING (The spots on the patient's arm are swollen, injection area  and left shoulder  all extremely iitchy swelling and peeling), RASH (THe spots got worse, approximately 24 or 25 spots around his knees, arms, back and hip,Red spots the size of quarters on sides of knees also on ankles and wrists,), HYPERSENSITIVITY (hypersensitivity reaction), PRURITUS (itchy), ERYTHEMA (redness) and URTICARIA (hives) had not resolved.        For mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular), the reporter did not provide any causality assessments.   It was reported that the patches on his knees were the size of tennis balls, the patches on his back and buttocks were the size of quarters. The patient went to the dermatologist and had a biopsy that came back inconclusive.   This case was linked to MOD-2021-271483 (Patient Link).   Most recent FOLLOW-UP information incorporated above includes: On 09-Aug-2021: Significant FU appended (Event info updated)