something is wrong with the frontal lobe of her brain; difficulty finding words when she speaks; weakness; disability to focus on things/Ability to focus has decreased; no appetite I eat half of what I used to; unable to move her arm without it hurting; sore arm; she has lost some weight; her nose gets stuffed up when she talks for a long time; dizziness is not normal; weird headache; exhaustion/overwhelming fatigue; Patient received full 4th dose of Moderna COVID-19 vaccine; This spontaneous case was reported by a consumer and describes the occurrence of HEAD DISCOMFORT (something is wrong with the frontal lobe of her brain), SPEECH DISORDER (difficulty finding words when she speaks), ASTHENIA (weakness), DISTURBANCE IN ATTENTION (disability to focus on things/Ability to focus has decreased) and DECREASED APPETITE (no appetite I eat half of what I used to) in an 83-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 059A21A, 052F21A, 003A21A and 012M20A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     The patient's past medical history included Lung cancer (lung cancer is NED (no evidence detected) status since she had the surgery in 2014) from 2008 to 2014 and Follicular lymphoma (Patient is in chronic remission since 2019) from 2016 to September 2019. Concurrent medical conditions included Allergy to chemicals (Red dye, blue dye), Vision abnormal (currently being treated for this condition, however treatment has been delayed due to the pandemic) since 07-Mar-2020, Benign secondary hypertension (Patient has had this for 30-40 years. Patient is currently being treated for this condition), Vestibular abnormalities (Patient is currently being treated for this condition) since 2021, Immunocompromised, Sleep apnoea (Sleep apnoea for which she requires oxygen at night while sleeping), Migraine and Blood pressure. Concomitant products included ATENOLOL for Blood pressure, CLONAZEPAM for Migraine, PARACETAMOL (ACETAMINOPHEN), LIOTHYRONINE, LEVOTHYROXINE SODIUM (UNITHROID), LOSARTAN POTASSIUM, COLECALCIFEROL (VITAMIN D [COLECALCIFEROL]), VITAMIN B COMPLEX (VITAMIN B [VITAMIN B COMPLEX]), MAGNESIUM CITRATE, CALCIUM CITRATE, POLYETHYLENE GLYCOL [MACROGOL], BRIMONIDINE TARTRATE, TIMOLOL MALEATE (COMBIGAN), CICLOSPORIN (RESTASIS), LATANOPROST, CARMELLOSE (REFRESH [CARMELLOSE]), ERYTHROMYCIN PROPIONATE (ERYTHROMYCIN [ERYTHROMYCIN PROPIONATE]), HYDROCODONE BITARTRATE, PARACETAMOL (NORCO) and MELATONIN for an unknown indication.   On 03-Feb-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) .5 milliliter. On 03-Mar-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to .5 milliliter. On 20-Aug-2021, received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to .5 milliliter. On 21-Jan-2022, received fourth dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular) dosage was changed to .5 milliliter. On 21-Jan-2022, the patient experienced HEAD DISCOMFORT (something is wrong with the frontal lobe of her brain), SPEECH DISORDER (difficulty finding words when she speaks), ASTHENIA (weakness), DISTURBANCE IN ATTENTION (disability to focus on things/Ability to focus has decreased), DECREASED APPETITE (no appetite I eat half of what I used to), LIMB DISCOMFORT (unable to move her arm without it hurting), PAIN IN EXTREMITY (sore arm), WEIGHT DECREASED (she has lost some weight), NASAL CONGESTION (her nose gets stuffed up when she talks for a long time), DIZZINESS (dizziness is not normal), HEADACHE (weird headache), FATIGUE (exhaustion/overwhelming fatigue) and PRODUCT ADMINISTRATION ERROR (Patient received full 4th dose of Moderna COVID-19 vaccine). The patient was treated with ACETAMINOPHEN at an unspecified dose and frequency. On 21-Jan-2022, PRODUCT ADMINISTRATION ERROR (Patient received full 4th dose of Moderna COVID-19 vaccine) had resolved. On 05-Feb-2022, LIMB DISCOMFORT (unable to move her arm without it hurting) and PAIN IN EXTREMITY (sore arm) had resolved. At the time of the report, HEAD DISCOMFORT (something is wrong with the frontal lobe of her brain), SPEECH DISORDER (difficulty finding words when she speaks), ASTHENIA (weakness), DISTURBANCE IN ATTENTION (disability to focus on things/Ability to focus has decreased), DECREASED APPETITE (no appetite I eat half of what I used to), WEIGHT DECREASED (she has lost some weight), NASAL CONGESTION (her nose gets stuffed up when she talks for a long time), DIZZINESS (dizziness is not normal), HEADACHE (weird headache) and FATIGUE (exhaustion/overwhelming fatigue) had not resolved.      DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): In January 2022, Weight: lost some weight (Low) lost some weight.         Patient received her 1st and 2nd dose. She said that she did not really had any unexpected reactions from those two doses. Patient received her 3rd dose and she said that she did not have any side effects from that vaccine and the 3rd dose worked for her. She stated that her doctor checked her antibody levels and according to the results, the 3rd dose worked in creating antibodies.   This case was linked to MOD-2021-253765 (Patient Link).