all three shots - HIVES ALL BODY; Terrible EOE; Very strong reaction to each vaccine; Pain from the first 2 shots that lasted for months until I got covid; Covid; Terrible EOE with esophagus spasms; This spontaneous case was reported by a consumer and describes the occurrence of OESOPHAGEAL SPASM (Terrible EOE with esophagus spasms), URTICARIA (all three shots - HIVES ALL BODY), EOSINOPHILIC OESOPHAGITIS (Terrible EOE), VACCINATION COMPLICATION (Very strong reaction to each vaccine) and PAIN (Pain from the first 2 shots that lasted for months until I got covid) in a 54-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     The patient's past medical history included Injection site reaction. Previously administered products included for Product used for unknown indication: Flu on 13-Sep-2021. Past adverse reactions to the above products included No adverse event with Flu. Concurrent medical conditions included Drug allergy (sulfa drug, delayed hives 5 days.), Drug allergy (Meloxicam, delayed swelling of lips and face.), Hay fever, Urticaria, Histamine intolerance (Hives worse with booster, vaccines. Histamine  intolerance from SIBO, antibiotics after 1 year.) since 01-Apr-2020, Menopause (Menopause issues, same comes and goes) since 01-Jan-2016 and Hypersensitivity. Concomitant products included FLUTICASONE PROPIONATE (FLOVENT), DESLORATADINE (CLARINEX [DESLORATADINE]) and VITAMIN D NOS for an unknown indication.   On 24-Mar-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 21-Apr-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. In July 2021, the patient experienced OESOPHAGEAL SPASM (Terrible EOE with esophagus spasms). On an unknown date, the patient experienced URTICARIA (all three shots - HIVES ALL BODY), EOSINOPHILIC OESOPHAGITIS (Terrible EOE), VACCINATION COMPLICATION (Very strong reaction to each vaccine), PAIN (Pain from the first 2 shots that lasted for months until I got covid) and COVID-19 (Covid). The patient was treated with CETIRIZINE HYDROCHLORIDE (ZYRTEC ALLERGY) for Adverse event, at an unspecified dose and frequency and ALUMINIUM HYDROXIDE, MAGNESIUM HYDROXIDE, SIMETICONE (PEPSID) for Adverse event, at an unspecified dose and frequency. At the time of the report, OESOPHAGEAL SPASM (Terrible EOE with esophagus spasms), URTICARIA (all three shots - HIVES ALL BODY), EOSINOPHILIC OESOPHAGITIS (Terrible EOE), VACCINATION COMPLICATION (Very strong reaction to each vaccine) and COVID-19 (Covid) outcome was unknown and PAIN (Pain from the first 2 shots that lasted for months until I got covid) had resolved.            Concomitant medications reported also included enzymes(DOA other).  Patient had terrible EOE with esophagus spasms that had occurred after the 2nd shot, and patient knew this is related to the moderna vaccine - lots of medical testing was done to make sure it wasn't a heart attack, stomach paralysis or Gallbladder issues etc. first time spasms happened in July 21. Hives were way worse this time. All over body constantly moving around - including around eyes and eyelids. beat red inflamed and itchy welds run together. Patient soaked in cool tub for hours to try and help. Took A lot of antihistamines that didn't help much. (next time will probably go for steriod injectionn, but tried not to this time). Patient had pain from the first 2 shots that lasted for months until patient got covid, then disappeared.  Company comment: This case concerns a 54-year-old, female patient with medical history of hypersensitivity, urticaria, hay fever, histamine intolerance and drug allergy, previously vaccinated with COVID-19 VACCINE ASTRAZENECA, who experienced the unexpected non serious events of eosinophilic esophagitis, oesophageal spasm, urticaria, vaccination complication, pain and COVID 19. The events occurred on an unknown date after the second dose of mRNA-1273. As reported, patient had terrible EOE with esophagus spasms that had occurred after the 2nd shot, first time spasms happened 1 month after second dose. The patient also experienced hives and had pain from the first 2 shots that lasted for months until patient got Covid, which then disappeared, as reported. Rechallenge was positive for event of hives. above mentioned medical history of hypersensitivity, urticaria and allergies remains a confounder. Based on the current available information, the mRNA-1273 does not contain a virus capable of causing COVID-19 infection after vaccination. The benefit-risk relationship of mRNA-1273 is not affected by this report.   This case was linked to MOD-2021-066057, MOD-2022-454673 (Patient Link).   Most recent FOLLOW-UP information incorporated above includes: On 20-Jan-2022: Follow up received included new events body rash, vaccine adverse reaction.; Sender's Comments: This case concerns a 54-year-old, female patient with medical history of hypersensitivity, urticaria, hay fever, histamine intolerance and drug allergy, previously vaccinated with COVID-19 VACCINE ASTRAZENECA, who experienced the unexpected non serious events of eosinophilic esophagitis, oesophageal spasm, urticaria, vaccination complication, pain and COVID 19. The events occurred on an unknown date after the second dose of mRNA-1273. As reported, patient had terrible EOE with esophagus spasms that had occurred after the 2nd shot, first time spasms happened 1 month after second dose. The patient also experienced hives and had pain from the first 2 shots that lasted for months until patient got Covid, which then disappeared, as reported. Rechallenge was positive for event of hives. above mentioned medical history of hypersensitivity, urticaria and allergies remains a confounder. Based on the current available information, the mRNA-1273 does not contain a virus capable of causing COVID-19 infection after vaccination. The benefit-risk relationship of mRNA-1273 is not affected by this report.