Heart disease; CARDIAC PAIN; Muscle tension/arm stress; ARM NUMBNESS; Increased blood pressure; This is a spontaneous report from a non-contactable consumer (patient).  A 75-year-old male patient received the second dose of BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE), intramuscular on 28Feb2021 (Batch/Lot number was not reported) as single dose for covid-19 immunisation; adalimumab (HUMIRA), subcutaneous from 2017 (Batch/Lot number was not reported) and ongoing, at 40 mg for crohn's disease.  Medical history included blood pressure high, Urine control, High cholesterol, Stomach upset, heart flow, Alcohol user, three to five bottles of beer on weekends (stopped 1986) , tobacco user, two or three cigars a day (Stopped 1986). Concomitant medications included lisinopril taken for blood pressure increased; finasteride taken for urine control; atorvastatin taken for blood cholesterol normal; pantoprazole taken for stomach upset; diltiazem hydrochloride (CARDIZEM) taken for an unspecified indication; acetylsalicylic acid (ASPIRIN (E.C.)) taken for heart flow; vitamin d3 taken for an unspecified indication; ferrous sulfate taken for urine; terazosin taken for urine control; probiotics taken for an unspecified indication. On unknown date, the patient experienced heart disease and arm numbness. on 04Mar2021, the patient experienced arm stress, cardiac pain and increased blood pressure. in Mar2021, the arm stress, cardiac pain and increased blood pressure resolved. COVID-19 VACCINE was also considered suspect.  Patient was hospitalized on 04Mar2021 due to heart disease, stress on his arm and pain on his heart. He had arm numbness. The Covid 19 vaccine second shot could have triggered the event. He underwent electrocardiogram and the result was fine. His blood pressure was going up but he could not remember the reading of his blood pressure during that time. Patient was advised to increase the dose of his medicines and was given with his  usual medications which were the Lisinopril, Finasteride, Terazosin, Atorvastatin, Vitamin B12, Fer-rous Sulfate and Pantoprazole during his hospitalization. He was discharged on 05 Mar 2021 and he recovered from the events stress in arm, cardiac pain and increased blood pressure a week af-ter his hospital discharge. Blood pressure went back to normal level. Patient could not remember the indication for Cardizem. Patient already received twodoses of CoVid 19 vaccine. The action taken in response to the events for adalimumab was dose not changed. The outcome of events Cardiac pain, Muscle tension,  Blood pressure increased was resolved in Mar2021, of event Numbness was recovering, of event Heart disease  was unknown.  The reporter's causality for the events of heart disease was not provided. the reporter's causality for the events of arm stress, cardiac pain, arm numbness and increased blood pressure with humira 40mg/0.4ml(adalimumab) was no reasonable possibility. There is no reasonable possibility that the events of heart disease, arm stress, cardiac pain, arm numbness and increased blood pressure are related to humira 40mg/0.4ml(adalimumab). The reporter's causality for all the events with Covid-19 vaccine was Not Reported.  No follow-up attempts are needed; information about lot/batch number cannot be obtained.