Severe depression; Body weakness/body is weak in the leg, arms, hands to the point; Dizziness; Falling; She can barely walk; she cant remember what bacteria she was positive for but she had an infection,; showing that she has some deterioration in the hips.; This is a spontaneous report received from contactable reporter(s) (Consumer or other non HCP) from medical information team.  A 66-year-old female patient received BNT162b2 (BNT162B2), on 25May2022 as dose 4 (booster), single (Batch/Lot number: unknown) at the age of 66 years for covid-19 immunisation. The patient's relevant medical history included: "Defibrillator/pacemaker insertion" (unspecified if ongoing); "Thyroid issues" (unspecified if ongoing). Concomitant medication(s) included: CLONAZEPAM; ALPRAZOLAM. Vaccination history included: BNT162b2 (DOSE 1, SINGLE; Lot number : EN6199), administration date: 05Mar2021, when the patient was 65-year-old, for COVID-19 immunization, reaction(s): "Severe depression", "body weakness / body is weak in the leg, arms, hands to the point", "Dizziness", "falling several times", "she can barely walk"; BNT162b2 (DOSE 2, SINGLE; Lot number : ER8733), administration date: 26Mar2021, when the patient was 65-year-old, for COVID-19 immunization, reaction(s): "Severe depression", "body weakness / body is weak in the leg, arms, hands to the point", "Dizziness", "falling several times", "she can barely walk"; BNT162b2 (DOSE 3 (BOOSTER), SINGLE; Lot is either 33030BD or 33030DD), administration date: 03Dec2021, when the patient was 65-year-old, for COVID-19 immunization, reaction(s): "Severe depression", "body weakness / body is weak in the leg, arms, hands to the point", "Dizziness", "falling several times", "she can barely walk".  The following information was reported: ASTHENIA (non-serious) with onset 2022, outcome "not recovered", described as "Body weakness/body is weak in the leg, arms, hands to the point"; DIZZINESS (non-serious) with onset 2022, outcome "unknown"; FALL (non-serious) with onset 2022, outcome "not recovered", described as "Falling"; DEPRESSION (non-serious) with onset 2022, outcome "not recovered", described as "Severe depression"; GAIT DISTURBANCE (non-serious) with onset 2022, outcome "unknown", described as "She can barely walk"; BACTERIAL INFECTION (non-serious) with onset 2022, outcome "unknown", described as "she cant remember what bacteria she was positive for but she had an infection,"; HIP DEFORMITY (non-serious) with onset 2022, outcome "unknown", described as "showing that she has some deterioration in the hips.".Relevant laboratory tests and procedures are available in the appropriate section.  Additional information: Caller wanted to know if the onset of body weakness and dizziness were related to the Pfizer COVID-19 Vaccine Gray Cap and if there was something to help handle this side effects. Caller stated that she called for her mom. She was calling in regards to the Pfizer COVID Vaccine. Ever since she has gotten it or actually every time she has gotten each dose, the patient experienced severe depression, her body was weak in the leg, arms, hands to the point she can barely walk and was falling several times. She also experiences dizziness each time, between the dizziness and weakness she has fallen a few times because of it. Caller was wondering if there was anything she could do to reverse the side effects or help. Caller stated that her mom had 5 doses of the COVID vaccine and all of them are Pfizer. Lot number for the fourth dose was reported as either FM7553 or FM7533. The patient also received fifth dose of Pfizer COVID Bivalent Vaccine on 26Oct2022 Lot was either GJ3275 or 6J3275 for covid-19 immunisation. Caller also clarified that each time with each dose, with the last dose being the worst, but each time her mom would experience Depression, Body weakness, and dizziness. During the call, caller's mom (withheld) says she thought she had muscular dystrophy or something like that. The Dizziness was on and off, it was not constant. The side effects happen with each vaccination, however the start of the side effects typically started a few days after getting the vaccine and gets worse. The patient recently had a brain scan clarifying it was actually a CT scan of the brain, back and neck. The patient also had labs done since she was suppose to be having her hip replaced next Friday. The CT scans results had nothing, when it came back, besides showing that she has some deterioration in the hips. For the labs, she recalls was was Blood work and they did a bacterial swab, she cant remember what bacteria she was positive for but she had an infection, The CT scans and lab work was back in Sep2022 she was guessing since the doctor appointment was in early Oct2022. There were no known allergies. Caller stated that her mom asked the doctor if she had muscular dystrophy, the doctor ruled that out, the doctor also said Parkinson's was ruled out, He ruled out all of that and said its not what it was, they don't know what it was, but just noticed it comes on every time she gets the COVID vaccines.  The information on the batch/lot number for BNT162b2 has been requested and will be submitted if and when received.; Sender's Comments: Linked Report(s) : 202201296028 Same patient, different dose and event.;