Kind of hurt during injection; feeling so bad, felt like ran over by a truck, not feel good; weak, weakness, unable hold head up, couldn't get up; headache font and back, terrific headache; flu like symptoms, felt like had flu, every step was an effort; severe chills; Not leave house, stayed on christmas; fever, 100 degrees, high fever; so sick, Sicker than a dog; This case was reported by a consumer via call center representative and described the occurrence of pain in a 80-year-old female patient who received Herpes zoster (Shingrix) for prophylaxis.   The patient's past medical history included shingles (Family History) (grandmother and uncle). Previously administered products included Zostavax with an associated reaction of no adverse event (received live shingles vaccine many years ago around the age of 65 (with no side effects)), flu vaccine with an associated reaction of no adverse event (with no side effects) and Covid Vaccine with an associated reaction of no adverse event (with no side effects). Concurrent medical conditions included eyeglasses wearer (wears reading glasses). Additional patient notes included negative history of headaches -the patient did not had headaches.   On 12th December 2022 09:00, the patient received the 1st dose of Shingrix (intramuscular). On 12th December 2022, immediately after receiving Shingrix, the patient experienced pain, feeling unwell, weakness, headache, influenza-like symptoms, chills, fever, sickness and activities of daily living impaired. The patient was treated with paracetamol (Tylenol). On an unknown date, the outcome of the pain, feeling unwell, weakness, headache, chills, fever and sickness were recovered/resolved and the outcome of the influenza-like symptoms and activities of daily living impaired were unknown.   The reporter considered the pain, feeling unwell, weakness, headache, chills and fever to be related to Shingrix. It was unknown if the reporter considered the influenza-like symptoms, sickness and activities of daily living impaired to be related to Shingrix.     Additional Information: GSK Receipt Date: 23-FEB-2023 Reporter's comment:  The reporter was the patient, she did not had an email.  The patient had Shingrix shot and it was given at her physician's office and did had the lot number of the shot administered.  The patient said that it kind of hurt during the injection. The patient took a Tylenol at lunchtime to prevent symptoms and sometime after lunch she said that she started feeling so bad that she could not hold my head up (due to weakness). On 12th December 2022, by 3:00, she was laying down in bed due to a headache in the front and back of her head. The patient was hurt so bad that she felt like she was ran over by a truck and she did not felt good at all and felt like she had the flu with severe chills. The patient had a fever and took Tylenol for the fever.  The Tylenol cut the fever down but did not did anything to help with the other symptoms.   On 12th December 2022, by 5:00 pm, fever came down. At 8 pm, she went to bed because she was so sick the fever was approaching 100 degrees so she took 2 Tylenol. On 13th December 2022 at 4 am, she was awake with a high fever and a terrific headache. On 13th December 2022, around 10 am her physician's office called and she told them she was, sicker than a dog. They advised her to continue to take Tylenol for 24 more hours and by about the 3rd day patient did not had a fever anymore. The patient stated that she was sick for 3 weeks and did not leave her house for 3 weeks which was not normal for her.  Usually she was an active person on the go and she felt like she had the flu and was so weak she could not get up.  The patient stated that every step was an effort and even stayed home during holidays. MD contacted that she was fine with GlaxoSmithKline (GSK) sending her a letter requesting her MD contact information.  She did not wanted to provide it at the time of the report because she wanted to obtain consent from her MD first.