They've diagnosed me with angioedema/eye swelling/eye pain/lacrimation increased,/eye pruritus/pallor and head discomfort; an auto immune disease; I've been suffering with daily swelling around my eyes and face; I can't seem to wash my hair with any product and it only seems to be worse when I use things on my face and eat certain foods; I asked doctor if i was allergic to things and he said no its purely down to what the jab has trigered in my body; I am sick of its tbh; I get headaches; This spontaneous case was reported by a patient and describes the occurrence of ANGIOEDEMA (They've diagnosed me with angioedema/eye swelling/eye pain/lacrimation increased,/eye pruritus/pallor and head discomfort) and AUTOIMMUNE DISORDER (an auto immune disease) in a female patient of an unknown age who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 prophylaxis. The occurrence of additional non-serious events is detailed below.     No Medical History information was reported.    In September 2021, the patient received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On an unknown date, the patient experienced ANGIOEDEMA (They've diagnosed me with angioedema/eye swelling/eye pain/lacrimation increased,/eye pruritus/pallor and head discomfort) (seriousness criterion medically significant), AUTOIMMUNE DISORDER (an auto immune disease) (seriousness criterion medically significant), SWELLING FACE (I've been suffering with daily swelling around my eyes and face), LOSS OF PERSONAL INDEPENDENCE IN DAILY ACTIVITIES (I can't seem to wash my hair with any product and it only seems to be worse when I use things on my face and eat certain foods), IMMUNISATION REACTION (I asked doctor if i was allergic to things and he said no its purely down to what the jab has trigered in my body), ILLNESS (I am sick of its tbh) and HEADACHE (I get headaches). The patient was treated with FEXOFENADINE at a dose of 180 milligram. At the time of the report, ANGIOEDEMA (They've diagnosed me with angioedema/eye swelling/eye pain/lacrimation increased,/eye pruritus/pallor and head discomfort), AUTOIMMUNE DISORDER (an auto immune disease) and SWELLING FACE (I've been suffering with daily swelling around my eyes and face) had not resolved and LOSS OF PERSONAL INDEPENDENCE IN DAILY ACTIVITIES (I can't seem to wash my hair with any product and it only seems to be worse when I use things on my face and eat certain foods), IMMUNISATION REACTION (I asked doctor if i was allergic to things and he said no its purely down to what the jab has trigered in my body), ILLNESS (I am sick of its tbh) and HEADACHE (I get headaches) outcome was unknown.            No concomitant medication information was provided. After administration of 2nd moderna dose patient had suffered with daily swelling around her eyes. She had really sore watery eyes and had a flare up too. Doctor could not help her because did not knew about it. She went private and was diagnosed with angioedema and immune disease which were triggered by the COVID jab. Patient was taking 4 antihistamines daily but when swelling bad it did not do anything. Patient could not seem to wash her hair with any products and its always seems to worse when patient used things on her face and eat certain foods. At the same time it was pretty inconsistent  though. Patient was waiting to be seen by an immunologist. Reaction always worse in morning when patient wake up (really bad swelling under the eyes or dark shiners and felt like she had been hit by bus as well as looks rough). It also strips the colour out of her face when it happened so she looks really pale.  Somedays it goes down, other days it did not or start flaring back up throughout the days. If it gets really bad it made her want to sleep and her head felt so heavy.  Company Comment: This is a spontaneous case concerning a female patient of an unknown age with no reported medical history, who experienced the unexpected, serious, events of Autoimmune Disorder and Angioedema were medically significant (IME).  Following the 2nd dose of the mRNA-1273 original vaccine, the patient has been suffering from daily swelling around the eyes and face, this was also accompanied by headaches and sore watery scratchy eyes. Consult with the physician was done and patient was diagnosed with Angioedema and Autoimmune Disease and was treated with antihistamines. No further information on risk factors, co morbidities, clinical course and management of the events was available in the report. The reported outcome of the events was unknown. The benefit-risk relationship of mRNA-1273 Original Vaccine is not affected by this report; Sender's Comments: This is a spontaneous case concerning a female patient of an unknown age with no reported medical history, who experienced the unexpected, serious, events of Autoimmune Disorder and Angioedema were medically significant (IME).  Following the 2nd dose of the mRNA-1273 original vaccine, the patient has been suffering from daily swelling around the eyes and face, this was also accompanied by headaches and sore watery scratchy eyes. Consult with the physician was done and patient was diagnosed with Angioedema and Autoimmune Disease and was treated with antihistamines. No further information on risk factors, co morbidities, clinical course and management of the events was available in the report. The reported outcome of the events was unknown. The benefit-risk relationship of mRNA-1273 Original Vaccine is not affected by this report.