Extreme swelling inside my upper and lower lip; Started to feel like a swelling inside my mouth and cheeks and around and under my tongue; Fatigue; Extreme swelling inside my upper and lower lip; Started to feel like a swelling inside my mouth and cheeks and around and under my tongue; Extreme swelling inside my upper and lower lip; Started to feel like a swelling inside my mouth and cheeks and around and under my tongue; This is a spontaneous report received from a contactable reporter(s) (Consumer or other non HCP). The reporter is the patient.  A female patient received BNT162b2 (BNT162B2), as dose 4 (booster), single (Lot number: FJ4991) for covid-19 immunisation. The patient's relevant medical history included: "Acid reflux" (unspecified if ongoing). Concomitant medication(s) included: PEPCID AC taken for gastrooesophageal reflux disease. Past drug history included: Omeprazole. Vaccination history included: Covid-19 vaccine (Primary Immunization series complete but unknown manufacturer), for COVID-19 immunization; Bnt162b2 (Dose 3 (Booster)), for COVID-19 Immunization. The following information was reported: LIP SWELLING (non-serious), SWELLING FACE (non-serious), MOUTH SWELLING (non-serious), outcome "unknown" and all described as "Extreme swelling inside my upper and lower lip; Started to feel like a swelling inside my mouth and cheeks and around and under my tongue"; FATIGUE (non-serious), outcome "unknown". Therapeutic measures were taken as a result of lip swelling, mouth swelling.  Additional information: Reporter stated that after the booster shot and patient was not sure if this was a true side effect or this was from something else but patient  had extreme swelling inside her upper and lower lip, similar to Canker sores but not truly a Canker sore because patient  have been rinsing with a rinse that she suggested and they were subsiding a lot more quickly than they ever have, you know when patient was younger. Patient  received this vaccine on Tuesday and by Wednesday evening patient started to feel like a swelling inside my mouth and cheeks and around and under my tongue and it was so similar to Canker sores and my pharmacist said that patient should call you to report it just for your data collecting evidence." Reporter stated, "Yes, that was correct and it still exists today which was now Saturday. Again, patient did not know if it was truly related. Patient normally take a drug for acid reflux but because patient was going for endoscopy this coming Thursday, patient was off Omeprazole and my doctor put me on Pepcid, just to kind of calm some of the acid reflux. So, patient do not know if the sores have anything to do with, you know more acidity in my mouth or not or if it was a true reaction. But my pharmacist said that patient should report it anyway because if you received any other call that have the same side effects then it would be helpful to know that I had a similar side effect." Reporter stated, "She gave me the whole print out and because I had the other vaccines, patient have a list of all the side effects but she said you were still collecting data for the second booster. This occurred after the second booster, patient know what all the other side effects are but patient only experienced a little bit of fatigue but nothing like the initial vaccine."  No follow-up attempts are possible. No further information is expected.