pain; looks like a chemical burn throughout their whole body; All the skin to shed/discolored; All the skin to shed/discolored; It broke out/I had like 5 spots on both hands on my palms/it was all over me/my face, my head, everywhere; my nails are going to come off; This is a spontaneous report received from a contactable reporter (Consumer or other non HCP) from medical information team. The reporter is the patient.  A 64-year-old female patient received BNT162b2, BNT162b2 omi ba.4-5 (BNT162B2, BNT162B2 OMI BA.4-5), on 22Oct2022 as dose 3 (booster), 0.3 ml single (Lot number: GJ6665, Expiration Date: 06Dec2022) at the age of 64 years, in left arm for COVID-19 immunisation. The patient's relevant medical history included: "Depression" (unspecified if ongoing); "Arthritis" (unspecified if ongoing); "Degenerative bone disease" (unspecified if ongoing); "Insomnia" (unspecified if ongoing); "Emphysema" (unspecified if ongoing); "COPD" (unspecified if ongoing); "PTSD (Post-traumatic stress disorder)" (unspecified if ongoing). The patient took concomitant medications. Vaccination history included: BNT162b2 (dose 1, single; lot number: EWO161; expiration date: 01Jul2021), administration date: 26Apr2021, when the patient was 63-year-old, for COVID-19 immunization; COVID-19 vaccine (dose 2, single; manufacturer unknown), administration date: 17May2021, when the patient was 63-year-old, for COVID-19 Immunization. The following information was reported: CHEMICAL BURN (hospitalization), outcome "not recovered", described as "looks like a chemical burn throughout their whole body"; SKIN EXFOLIATION (hospitalization), SKIN DISCOLOURATION (hospitalization), outcome "not recovered" and all described as "All the skin to shed/discolored"; RASH MACULAR (hospitalization), outcome "not recovered", described as "It broke out/I had like 5 spots on both hands on my palms/it was all over me/my face, my head, everywhere"; NAIL DISORDER (hospitalization), outcome "unknown", described as "my nails are going to come off"; PAIN (hospitalization), outcome "unknown". The patient was hospitalized for chemical burn, skin exfoliation, skin discolouration, rash macular, nail disorder (start date: Nov2022, discharge date: Nov2022, hospitalization duration: 3 day(s)); for pain (start date: Nov2022, discharge date: Nov2022). The event "it broke out/i had like 5 spots on both hands on my palms/it was all over me/my face, my head, everywhere" required emergency room visit. Therapeutic measures were taken as a result of pain. Clinical course: About 20 some days, 20-25 days after the shot, patient wound of in the hospital for 3 days. And this was the only thing she can think of. She was still dealing with the problem she had. They don't have a name for it because she said nobody knew what it was. They let the patient go. It took another two three weeks for all the skin to shed and like she said she has discolored. She still has some repercussions from whatever happened. This was the only thing she can honestly thought of that she did any different, that was getting her booster shot. She was just seeing or wondering too if anybody else had a reaction that looks like a chemical burn throughout their whole body. She asked if everybody's skin did peel. She does have photos of it, and it broke out, it started in her hand, she woke up one morning and she had like 5 spots on both hands on palms. Then, within like a day and a half she was in the emergency room because it was all over her. Once it started it didn't stop it was just like everywhere, her face, her head, everywhere. This was the only thing she can think of. She was still having effects. The patient would like to know how long a reaction could take before exposing itself. On 20Mar2023, the patient stated she went in the hospital for 3 days in about mid-Nov2022. It was about 20 plus days after the inoculation. They kept the patient for 3 days and they could not figure out what was causing it and just its has been bothering her because she still have some symptoms of it last. What happened was like, she broke out but it her whole body and she's talking about her mouth, inside her mouth, her chest, her back, her butt, various areas, bottom of her feet and what happened was that her skin would peel off and she would have raw skin. It was so horrible, it hurts so bad. Nobody can figure it out. The patient reported she just have the revisal of that like her nails were going to come off. They are still peeling and she have the bottom of her feet would never feel the same, it never, they just feel not the same and her skin was discolored. They tried a few things on her, but they could not figure out what it was, so they were treating her because they could, the CDC could not figured it out, the center could not figure out. Dermatologist could not figure out. The patient left home but with no answers and it was just recently and she was reading some of the effects from COVID shots, side effects on people of her age and it was stating for some of them that they could become as long as 23 to 30 days after the injections. The patient asked about the time she was into the emergency the first time and then within a day and a half she gained COVID back in the emergency as being kept. So, when she spent 3 days in there, everybody came and checked on her. All she took was her regular meds, basically in pain medication. So much pain. The patient reported that she takes a stool softener, a laxative and a fiber (daily) - as concomitant drugs.  The information on the batch/lot number for BNT162b2, BNT162b2 omi ba.4-5 has been requested and will be submitted if and when received.  Follow-up (20Mar2023): This is a spontaneous follow-up report received from same contactable consumer (patient). Updated information includes: patient (added age), medical history (added all), historical vaccine (updated vaccine used for dose 1 and dose 2), suspect drug (updated dose number to dose 3; added vaccination date, route, site, lot number, expiration date), event (added nail disorder, pain), and clinical course.; Sender's Comments: Linked Report(s) : US-PFIZER INC-PV202300054246 same patient and drug; different dose and event;