Redness the size of a playing card at the injection site which spread to the neck; This area was hot and painful, rated at a 10/10/ she has to let her arm hang or raise it over her head to relieve the pain; The pain was so bad she was vomiting; This area was hot and painful, rated at a 10/10; Redness the size of a playing card at the injection site which spread to the neck; Sitting is uncomfortable; This spontaneous case was reported by a consumer and describes the occurrence of VACCINATION SITE ERYTHEMA (Redness the size of a playing card at the injection site which spread to the neck), VACCINATION SITE PAIN (This area was hot and painful, rated at a 10/10/ she has to let her arm hang or raise it over her head to relieve the pain), VOMITING (The pain was so bad she was vomiting), VACCINATION SITE WARMTH (This area was hot and painful, rated at a 10/10) and ERYTHEMA (Redness the size of a playing card at the injection site which spread to the neck) in a 66-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 01CT21-2A, 012FUA and 041L20A) for COVID-19 vaccination. The occurrence of additional non-serious events is detailed below.     No Medical History information was reported.   On 17-Jan-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 27-Feb-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 19-Nov-2021, received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On 05-Apr-2022, received fourth dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On an unknown date, the patient experienced VACCINATION SITE ERYTHEMA (Redness the size of a playing card at the injection site which spread to the neck), VACCINATION SITE PAIN (This area was hot and painful, rated at a 10/10/ she has to let her arm hang or raise it over her head to relieve the pain), VOMITING (The pain was so bad she was vomiting), VACCINATION SITE WARMTH (This area was hot and painful, rated at a 10/10), ERYTHEMA (Redness the size of a playing card at the injection site which spread to the neck) and DISCOMFORT (Sitting is uncomfortable). The patient was treated with IBUPROFEN (ADVIL [IBUPROFEN]) for Vaccination site pain, at an unspecified dose and frequency; PARACETAMOL (TYLENOL) for Vaccination site pain, at an unspecified dose and frequency; NABUMETONE (RELAFEN) for Vaccination site pain, at an unspecified dose and frequency and Manual therapy (chiropractor, Ice) for Vaccination site pain. At the time of the report, VACCINATION SITE ERYTHEMA (Redness the size of a playing card at the injection site which spread to the neck), VOMITING (The pain was so bad she was vomiting), VACCINATION SITE WARMTH (This area was hot and painful, rated at a 10/10), ERYTHEMA (Redness the size of a playing card at the injection site which spread to the neck) and DISCOMFORT (Sitting is uncomfortable) outcome was unknown and VACCINATION SITE PAIN (This area was hot and painful, rated at a 10/10/ she has to let her arm hang or raise it over her head to relieve the pain) had not resolved.            No concomitant information was reported.  The patient had discussed symptoms with doctor, and that pain had continued to increased. Patient had to let arm hang or raised that over head to relieve the pain. Patient also slept with arm up.  The patient was using heat, ice and seeing a chiropractor for pain. Patient talked to doctor and asked for an magnetic resonance imaging (MRI) so that patient might be able to identify the source of her pain.   This case was linked to MOD-2022-555082 (Patient Link).